Effect of External Loading on Force and Power Production During Plyometric Push-ups.

PubMed

Hinshaw, Taylour J; Stephenson, Mitchell L; Sha, Zhanxin; Dai, Boyi

2018-04-01

Hinshaw, TJ, Stephenson, ML, Sha, Z, and Dai, B. Effect of external loading on force and power production during plyometric push-ups. J Strength Cond Res 32(4): 1099-1108, 2018-One common exercise to train upper-body strength and power is the push-up. Training at the loads that would produce the greatest power is an effective way to increase peak power. The purpose of the current study was to quantify the changes in peak force, peak power, and peak velocity among a modified plyometric push-up and plyometric push-ups with or without external loading in physically active young adults. Eighteen male and 17 female participants completed 4 push-ups: (a) modified plyometric push-up on the knees, (b) plyometric push-up without external loading, (c) plyometric push-up with an external load of 5% of body weight, and (d) plyometric push-up with an external load of 10% of body weight. Two force platforms were set up to collect vertical ground reaction forces at the hands and feet. The modified plyometric push-up demonstrated the lowest force, power, and velocity (5.4≥ Cohen's dz ≥1.2). Peak force and force at peak velocity increased (3.8≥ Cohen's dz ≥0.3) and peak velocity and velocity at peak power decreased (1.4≥ Cohen's dz ≥0.8) for the push-up without external loading compared with the 2 push-ups with external loading. No significant differences were observed for peak power among the push-ups with or without external loading (0.4≥ Cohen's dz ≥0.1). Although peak power is similar with or without external loading, push-ups without external loading may be more beneficial for a quick movement, and push-ups with external loading may be more beneficial for a greater force production.

Determination of current loads of floating platform for special purposes

NASA Astrophysics Data System (ADS)

Ma, Guang-ying; Yao, Yun-long; Zhao, Chen-yao

2017-08-01

This article studied a new floating offshore platform for special purposes, which was assembled by standard floating modules. The environmental load calculation of the platform is an important part of the research of the ocean platform, which has always been paid attention to by engineers. In addition to wave loads, the wind loads and current loads are also important environmental factors that affect the dynamic response of the offshore platform. The current loads on the bottom structure should not be ignored. By Fluent software, the hydrostatic conditions and external current loads of the platform were calculated in this paper. The coefficient which is independent of the current velocity, namely, current force coefficient, can be fitted through current loads, which can be used for the consequent hydrodynamic and mooring analyses.

14 CFR 133.17 - Requirements for issuance of a rotorcraft external-load operator certificate.

Code of Federal Regulations, 2010 CFR

2010-01-01

... external-load operator certificate. 133.17 Section 133.17 Aeronautics and Space FEDERAL AVIATION...: CERTIFICATION AND OPERATIONS ROTORCRAFT EXTERNAL-LOAD OPERATIONS Certification Rules § 133.17 Requirements for... §§ 133.19, 133.21, and 133.23, the Administrator issues a Rotorcraft External-Load Operator Certificate...

Quantification of baseline pupillary response and task-evoked pupillary response during constant and incremental task load.

PubMed

Mosaly, Prithima R; Mazur, Lukasz M; Marks, Lawrence B

2017-10-01

The methods employed to quantify the baseline pupil size and task-evoked pupillary response (TEPR) may affect the overall study results. To test this hypothesis, the objective of this study was to assess variability in baseline pupil size and TEPR during two basic working memory tasks: constant load of 3-letters memorisation-recall (10 trials), and incremental load memorisation-recall (two trials of each load level), using two commonly used methods (1) change from trail/load specific baseline, (2) change from constant baseline. Results indicated that there was a significant shift in baseline between the trails for constant load, and between the load levels for incremental load. The TEPR was independent of shifts in baseline using method 1 only for constant load, and method 2 only for higher levels of incremental load condition. These important findings suggest that the assessment of both the baseline and methods to quantify TEPR are critical in ergonomics application, especially in studies with small number of trials per subject per condition. Practitioner Summary: Quantification of TEPR can be affected by shifts in baseline pupil size that are most likely affected by non-cognitive factors when other external factors are kept constant. Therefore, quantification methods employed to compute both baseline and TEPR are critical in understanding the information processing of humans in practical ergonomics settings.

Poor phonetic perceivers are affected by cognitive load when resolving talker variability

PubMed Central

Antoniou, Mark; Wong, Patrick C. M.

2015-01-01

Speech training paradigms aim to maximise learning outcomes by manipulating external factors such as talker variability. However, not all individuals may benefit from such manipulations because subject-external factors interact with subject-internal ones (e.g., aptitude) to determine speech perception and/or learning success. In a previous tone learning study, high-aptitude individuals benefitted from talker variability, whereas low-aptitude individuals were impaired. Because increases in cognitive load have been shown to hinder speech perception in mixed-talker conditions, it has been proposed that resolving talker variability requires cognitive resources. This proposal leads to the hypothesis that low-aptitude individuals do not use their cognitive resources as efficiently as those with high aptitude. Here, high- and low-aptitude subjects identified pitch contours spoken by multiple talkers under high and low cognitive load conditions established by a secondary task. While high-aptitude listeners outperformed low-aptitude listeners across load conditions, only low-aptitude listeners were impaired by increased cognitive load. The findings suggest that low-aptitude listeners either have fewer available cognitive resources or are poorer at allocating attention to the signal. Therefore, cognitive load is an important factor when considering individual differences in speech perception and training paradigms. PMID:26328675

Poor phonetic perceivers are affected by cognitive load when resolving talker variability.

PubMed

Antoniou, Mark; Wong, Patrick C M

2015-08-01

Speech training paradigms aim to maximise learning outcomes by manipulating external factors such as talker variability. However, not all individuals may benefit from such manipulations because subject-external factors interact with subject-internal ones (e.g., aptitude) to determine speech perception and/or learning success. In a previous tone learning study, high-aptitude individuals benefitted from talker variability, whereas low-aptitude individuals were impaired. Because increases in cognitive load have been shown to hinder speech perception in mixed-talker conditions, it has been proposed that resolving talker variability requires cognitive resources. This proposal leads to the hypothesis that low-aptitude individuals do not use their cognitive resources as efficiently as those with high aptitude. Here, high- and low-aptitude subjects identified pitch contours spoken by multiple talkers under high and low cognitive load conditions established by a secondary task. While high-aptitude listeners outperformed low-aptitude listeners across load conditions, only low-aptitude listeners were impaired by increased cognitive load. The findings suggest that low-aptitude listeners either have fewer available cognitive resources or are poorer at allocating attention to the signal. Therefore, cognitive load is an important factor when considering individual differences in speech perception and training paradigms.

The Influence of External Load on Quadriceps Muscle and Tendon Dynamics during Jumping.

PubMed

Earp, Jacob E; Newton, Robert U; Cormie, Prue; Blazevich, Anthony J

2017-11-01

Tendons possess both viscous (rate-dependent) and elastic (rate-independent) properties that determine tendon function. During high-speed movements external loading increases both the magnitude (FT) and rate (RFDT) of tendon loading. The influence of external loading on muscle and tendon dynamics during maximal vertical jumping was explored. Ten resistance-trained men performed parallel-depth, countermovement vertical jumps with and without additional load (0%, 30%, 60%, and 90% of maximum squat lift strength), while joint kinetics and kinematics, quadriceps tendon length (LT) and patellar tendon FT and RFDT were estimated using integrated ultrasound, motion analysis and force platform data and muscle tendon modelling. Estimated FT and RFDT, but not peak LT, increased with external loading. Temporal comparisons between 0% and 90% loads revealed that FT was greater with 90% loading throughout the majority of the movement (11%-81% and 87%-95% movement duration). However, RFDT was greater with 90% load only during the early movement initiation phase (8%-15% movement duration) but was greater in the 0% load condition later in the eccentric phase (27%-38% movement duration). LT was longer during the early movement (12%-23% movement duration) but shorter in the late eccentric and early concentric phases (48%-55% movement duration) with 90% load. External loading positively influenced peak FT and RFDT but tendon strain appeared unaffected, suggesting no additive effect of external loading on patellar tendon lengthening during human jumping. Temporal analysis revealed that external loading resulted in a large initial RFDT that may have caused dynamic stiffening of the tendon and attenuated tendon strain throughout the movement. These results suggest that external loading influences tendon lengthening in both a load- and movement-dependent manner.

Validation of a dynamic linked segment model to calculate joint moments in lifting.

PubMed

de Looze, M P; Kingma, I; Bussmann, J B; Toussaint, H M

1992-08-01

A two-dimensional dynamic linked segment model was constructed and applied to a lifting activity. Reactive forces and moments were calculated by an instantaneous approach involving the application of Newtonian mechanics to individual adjacent rigid segments in succession. The analysis started once at the feet and once at a hands/load segment. The model was validated by comparing predicted external forces and moments at the feet or at a hands/load segment to actual values, which were simultaneously measured (ground reaction force at the feet) or assumed to be zero (external moments at feet and hands/load and external forces, beside gravitation, at hands/load). In addition, results of both procedures, in terms of joint moments, including the moment at the intervertebral disc between the fifth lumbar and first sacral vertebra (L5-S1), were compared. A correlation of r = 0.88 between calculated and measured vertical ground reaction forces was found. The calculated external forces and moments at the hands showed only minor deviations from the expected zero level. The moments at L5-S1, calculated starting from feet compared to starting from hands/load, yielded a coefficient of correlation of r = 0.99. However, moments calculated from hands/load were 3.6% (averaged values) and 10.9% (peak values) higher. This difference is assumed to be due mainly to erroneous estimations of the positions of centres of gravity and joint rotation centres. The estimation of the location of L5-S1 rotation axis can affect the results significantly. Despite the numerous studies estimating the load on the low back during lifting on the basis of linked segment models, only a few attempts to validate these models have been made. This study is concerned with the validity of the presented linked segment model. The results support the model's validity. Effects of several sources of error threatening the validity are discussed. Copyright © 1992. Published by Elsevier Ltd.

Measuring abnormal movements in free-swimming fish with accelerometers: implications for quantifying tag and parasite load.

PubMed

Broell, Franziska; Burnell, Celene; Taggart, Christopher T

2016-03-01

Animal-borne data loggers allow movement, associated behaviours and energy expenditure in fish to be quantified without direct observations. As with any tagging, tags that are attached externally may adversely affect fish behaviour, swimming efficiency and survival. We report on free-swimming wild Atlantic cod (Gadus morhua) held in a large mesocosm that exhibited distinctly aberrant rotational swimming (scouring) when externally tagged with accelerometer data loggers. To quantify the phenomenon, the cod were tagged with two sizes of loggers (18 and 6 g; <2% body mass) that measured tri-axial acceleration at 50 Hz. An automated algorithm, based on body angular rotation, was designed to extract the scouring movements from the acceleration signal (98% accuracy). The algorithm also identified the frequency pattern and associated energy expenditure of scouring in relation to tag load (% body weight). The average per cent time spent scouring (5%) was independent of tag load. The vector of the dynamic body acceleration (VeDBA), used as a proxy for energy expenditure, increased with tag load (r(2)=0.51), and suggests that fish with large tags spent more energy when scouring than fish with small tags. The information allowed us to determine potential detrimental effects of an external tag on fish behaviour and how these effects may be mitigated by tag size. The algorithm can potentially identify similar rotational movements associated with spawning, courtship, feeding and parasite-load shedding in the wild. The results infer a more careful interpretation of data derived from external tags and the careful consideration of tag type, drag, buoyancy and placement, as well as animal buoyancy and species. © 2016. Published by The Company of Biologists Ltd.

29 CFR 1926.958 - External load helicopters.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 8 2010-07-01 2010-07-01 false External load helicopters. 1926.958 Section 1926.958 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR... External load helicopters. In all operations performed using a rotorcraft for moving or placing external...

29 CFR 1926.958 - External load helicopters.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 29 Labor 8 2014-07-01 2014-07-01 false External load helicopters. 1926.958 Section 1926.958 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR... External load helicopters. In all operations performed using a rotorcraft for moving or placing external...

29 CFR 1926.958 - External load helicopters.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 29 Labor 8 2011-07-01 2011-07-01 false External load helicopters. 1926.958 Section 1926.958 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR... External load helicopters. In all operations performed using a rotorcraft for moving or placing external...

29 CFR 1926.958 - External load helicopters.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 29 Labor 8 2012-07-01 2012-07-01 false External load helicopters. 1926.958 Section 1926.958 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR... External load helicopters. In all operations performed using a rotorcraft for moving or placing external...

29 CFR 1926.958 - External load helicopters.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 29 Labor 8 2013-07-01 2013-07-01 false External load helicopters. 1926.958 Section 1926.958 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR... External load helicopters. In all operations performed using a rotorcraft for moving or placing external...

46 CFR 154.408 - Cargo tank external pressure load.

Code of Federal Regulations, 2010 CFR

2010-10-01

... minimum internal pressure (maximum vacuum), and the maximum external pressure to which any portion of the... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo tank external pressure load. 154.408 Section 154... Equipment Cargo Containment Systems § 154.408 Cargo tank external pressure load. For the calculation...

Serration Behavior of a Zr-Based Metallic Glass Under Different Constrained Loading Conditions

NASA Astrophysics Data System (ADS)

Yang, G. N.; Gu, J. L.; Chen, S. Q.; Shao, Y.; Wang, H.; Yao, K. F.

2016-11-01

To understand the plastic behavior and shear band dynamics of metallic glasses (MGs) being tuned by the external constraint, uniaxial compression tests were performed on Zr41.2Ti13.8Cu12.5Ni10.0Be22.5 MG samples with aspect ratios of 0.5:1, 1:1, 1.5:1, 2:1, 2.5:1, and 3:1. Better plasticity was observed for the samples with smaller aspect ratio (under higher constraint degree). In the beginning of yielding, increasing serration (jerky stress drop) size on the loading curves was noticed for all samples. Statistical analysis of the serration patterns indicated that the small stress-drop serrations and large stress-drop serrations follow self-organized critical and chaotic dynamics, respectively. Under constrained loading, the large stress-drop serrations are depressed, while the small stress-drop serrations are less affected. When changing the external constraint level by varying the sample aspect ratio, the serration pattern, shear band dynamics, and plastic behavior will change accordingly. This study provides a perspective from tuning shear band dynamics to understand the plastic behavior of MGs under different external constraint.

The relationships between internal and external training load models during basketball training.

PubMed

Scanlan, Aaron T; Wen, Neal; Tucker, Patrick S; Dalbo, Vincent J

2014-09-01

The present investigation described and compared the internal and external training loads during basketball training. Eight semiprofessional male basketball players (mean ± SD, age: 26.3 ± 6.7 years; stature: 188.1 ± 6.2 cm; body mass: 92.0 ± 13.8 kg) were monitored across a 7-week period during the preparatory phase of the annual training plan. A total of 44 total sessions were monitored. Player session ratings of perceived exertion (sRPE), heart rate, and accelerometer data were collected across each training session. Internal training load was determined using the sRPE, training impulse (TRIMP), and summated-heart-rate-zones (SHRZ) training load models. External training load was calculated using an established accelerometer algorithm. Pearson product-moment correlations with 95% confidence intervals (CIs) were used to determine the relationships between internal and external training load models. Significant moderate relationships were observed between external training load and the sRPE (r42 = 0.49, 95% CI = 0.23-0.69, p < 0.001) and TRIMP models (r42 = 0.38, 95% CI = 0.09-0.61, p = 0.011). A significant large correlation was evident between external training load and the SHRZ model (r42 = 0.61, 95% CI = 0.38-0.77, p < 0.001). Although significant relationships were found between internal and external training load models, the magnitude of the correlations and low commonality suggest that internal training load models measure different constructs of the training process than the accelerometer training load model in basketball settings. Basketball coaching and conditioning professionals should not assume a linear dose-response between accelerometer and internal training load models during training and are recommended to combine internal and external approaches when monitoring training load in players.

Magnetically Controllable Polymer Nanotubes from a Cyclized Crosslinker for Site-Specific Delivery of Doxorubicin

PubMed Central

Newland, Ben; Leupelt, Daniel; Zheng, Yu; Thomas, Laurent S. V.; Werner, Carsten; Steinhart, Martin; Wang, Wenxin

2015-01-01

Externally controlled site specific drug delivery could potentially provide a means of reducing drug related side effects whilst maintaining, or perhaps increasing therapeutic efficiency. The aim of this work was to develop a nanoscale drug carrier, which could be loaded with an anti-cancer drug and be directed by an external magnetic field. Using a single, commercially available monomer and a simple one-pot reaction process, a polymer was synthesized and crosslinked within the pores of an anodized aluminum oxide template. These polymer nanotubes (PNT) could be functionalized with iron oxide nanoparticles for magnetic manipulation, without affecting the large internal pore, or inherent low toxicity. Using an external magnetic field the nanotubes could be regionally concentrated, leaving areas devoid of nanotubes. Lastly, doxorubicin could be loaded to the PNTs, causing increased toxicity towards neuroblastoma cells, rendering a platform technology now ready for adaptation with different nanoparticles, degradable pre-polymers, and various therapeutics. PMID:26619814

Effects of BOSU ball(s) during sit-ups with body weight and added resistance on core muscle activation.

PubMed

Saeterbakken, Atle H; Andersen, Vidar; Jansson, June; Kvellestad, Ann C; Fimland, Marius S

2014-12-01

The objective of this study was to assess the electromyographic activity of the rectus abdominis (upper and lower part) and external oblique during sit-ups performed on BOSU ball(s). Twenty-four men participated in a familiarization session, and in the next session, they performed the experimental tests in randomized order. The sit-ups were performed with 10 repetitions with body weight and with 10 repetition maximum (10RM) using elastic bands as external resistance under 4 different conditions: (a) on a stable surface, (b) with the BOSU ball under their feet (dome side down, lower-body instability), (c) BOSU ball under the low back (dome side up, upper-body instability), and (d) with BOSU balls under both feet and the low back (dual instability). The feet were not attached to the surface. We observed that with body weight, external oblique activation was decreased by upper-body instability and dual instability by 22-24% (p = 0.002-0.006), whereas the rectus abdominis was not affected by the surface. Using 10RM loads, the upper and lower rectus abdominis activities were increased by upper body and dual instability by 21-24% compared with that for a stable surface (P ≤ 0.001-0.036). Further, lower-body instability did not affect muscle activities significantly with either load for any condition. Hence, BOSU balls under the low back can increase and decrease abdominal muscle activation depending on the load, whereas placing a BOSU ball under the feet with the dome side down had little impact.

Nonlinear ultrasonic imaging method for closed cracks using subtraction of responses at different external loads.

PubMed

Ohara, Yoshikazu; Horinouchi, Satoshi; Hashimoto, Makoto; Shintaku, Yohei; Yamanaka, Kazushi

2011-08-01

To improve the selectivity of closed cracks for objects other than cracks in ultrasonic imaging, we propose an extension of a novel imaging method, namely, subharmonic phased array for crack evaluation (SPACE) as well as another approach using the subtraction of responses at different external loads. By applying external static or dynamic loads to closed cracks, the contact state in the cracks varies, resulting in an intensity change of responses at cracks. In contrast, objects other than cracks are independent of external load. Therefore, only cracks can be extracted by subtracting responses at different loads. In this study, we performed fundamental experiments on a closed fatigue crack formed in an aluminum alloy compact tension (CT) specimen using the proposed method. We examined the static load dependence of SPACE images and the dynamic load dependence of linear phased array (PA) images by simulating the external loads with a servohydraulic fatigue testing machine. By subtracting the images at different external loads, we show that this method is useful in extracting only the intensity change of responses related to closed cracks, while canceling the responses of objects other than cracks. Copyright © 2010 Elsevier B.V. All rights reserved.

Collapse of Corroded Pipelines under Combined Tension and External Pressure

PubMed Central

Ye, Hao; Yan, Sunting; Jin, Zhijiang

2016-01-01

In this work, collapse of corroded pipeline under combined external pressure and tension is investigated through numerical method. Axially uniform corrosion with symmetric imperfections is firstly considered. After verifying with existing experimental results, the finite element model is used to study the effect of tension on collapse pressure. An extensive parametric study is carried out using Python script and FORTRAN subroutine to investigate the influence of geometric parameters on the collapse behavior under combined loads. The results are used to develop an empirical equation for estimating the collapse pressure under tension. In addition, the effects of loading path, initial imperfection length, yielding anisotropy and corrosion defect length on the collapse behavior are also investigated. It is found that tension has a significant influence on collapse pressure of corroded pipelines. Loading path and anisotropic yielding are also important factors affecting the collapse behavior. For pipelines with relatively long corrosion defect, axially uniform corrosion models could be used to estimate the collapse pressure. PMID:27111544

Bond–Slip Relationship for CFRP Sheets Externally Bonded to Concrete under Cyclic Loading

PubMed Central

Li, Ke; Cao, Shuangyin; Yang, Yue; Zhu, Juntao

2018-01-01

The objective of this paper was to explore the bond–slip relationship between carbon fiber-reinforced polymer (CFRP) sheets and concrete under cyclic loading through experimental and analytical approaches. Modified beam tests were performed in order to gain insight into the bond–slip relationship under static and cyclic loading. The test variables are the CFRP-to-concrete width ratio, and the bond length of the CFRP sheets. An analysis of the test results in this paper and existing test results indicated that the slope of the ascending segment of the bond–slip curve decreased with an increase in the number of load cycles, but the slip corresponding to the maximum shear stress was almost invariable as the number of load cycles increased. In addition, the rate of reduction in the slope of the ascending range of the bond–slip curve during cyclic loading decreased as the concrete strength increased, and increased as the load level or CFRP-to-concrete width ratio enhanced. However, these were not affected by variations in bond length if the residual bond length was longer than the effective bond length. A bilinear bond–slip model for CFRP sheets that are externally bonded to concrete under cyclic loading, which considered the effects of the cyclic load level, concrete strength, and CFRP-to-concrete ratio, was developed based on the existing static bond–slip model. The accuracy of this proposed model was verified by a comparison between this proposed model and test results. PMID:29495383

Bond-Slip Relationship for CFRP Sheets Externally Bonded to Concrete under Cyclic Loading.

PubMed

Li, Ke; Cao, Shuangyin; Yang, Yue; Zhu, Juntao

2018-02-26

The objective of this paper was to explore the bond-slip relationship between carbon fiber-reinforced polymer (CFRP) sheets and concrete under cyclic loading through experimental and analytical approaches. Modified beam tests were performed in order to gain insight into the bond-slip relationship under static and cyclic loading. The test variables are the CFRP-to-concrete width ratio, and the bond length of the CFRP sheets. An analysis of the test results in this paper and existing test results indicated that the slope of the ascending segment of the bond-slip curve decreased with an increase in the number of load cycles, but the slip corresponding to the maximum shear stress was almost invariable as the number of load cycles increased. In addition, the rate of reduction in the slope of the ascending range of the bond-slip curve during cyclic loading decreased as the concrete strength increased, and increased as the load level or CFRP-to-concrete width ratio enhanced. However, these were not affected by variations in bond length if the residual bond length was longer than the effective bond length. A bilinear bond-slip model for CFRP sheets that are externally bonded to concrete under cyclic loading, which considered the effects of the cyclic load level, concrete strength, and CFRP-to-concrete ratio, was developed based on the existing static bond-slip model. The accuracy of this proposed model was verified by a comparison between this proposed model and test results.

14 CFR 27.865 - External loads.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS... must be shown by analysis, test, or both, that the rotorcraft external load attaching means for rotorcraft-load combinations to be used for nonhuman external cargo applications can withstand a limit static...

14 CFR 27.865 - External loads.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS... must be shown by analysis, test, or both, that the rotorcraft external load attaching means for rotorcraft-load combinations to be used for nonhuman external cargo applications can withstand a limit static...

14 CFR 27.865 - External loads.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS... must be shown by analysis, test, or both, that the rotorcraft external load attaching means for rotorcraft-load combinations to be used for nonhuman external cargo applications can withstand a limit static...

14 CFR 27.865 - External loads.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS... must be shown by analysis, test, or both, that the rotorcraft external load attaching means for rotorcraft-load combinations to be used for nonhuman external cargo applications can withstand a limit static...

14 CFR 27.865 - External loads.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS... must be shown by analysis, test, or both, that the rotorcraft external load attaching means for rotorcraft-load combinations to be used for nonhuman external cargo applications can withstand a limit static...

14 CFR 29.865 - External loads.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS...) It must be shown by analysis, test, or both, that the rotorcraft external load attaching means for rotorcraft-load combinations to be used for nonhuman external cargo applications can withstand a limit static...

14 CFR 29.865 - External loads.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS...) It must be shown by analysis, test, or both, that the rotorcraft external load attaching means for rotorcraft-load combinations to be used for nonhuman external cargo applications can withstand a limit static...

14 CFR 29.865 - External loads.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS...) It must be shown by analysis, test, or both, that the rotorcraft external load attaching means for rotorcraft-load combinations to be used for nonhuman external cargo applications can withstand a limit static...

14 CFR 29.865 - External loads.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS...) It must be shown by analysis, test, or both, that the rotorcraft external load attaching means for rotorcraft-load combinations to be used for nonhuman external cargo applications can withstand a limit static...

14 CFR 29.865 - External loads.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS...) It must be shown by analysis, test, or both, that the rotorcraft external load attaching means for rotorcraft-load combinations to be used for nonhuman external cargo applications can withstand a limit static...

Interannual and long-term changes in the trophic state of a multibasin lake: Effects of morphology, climate, winter aeration, and beaver activity

USGS Publications Warehouse

Robertson, Dale M.; Rose, William; Reneau, Paul C.

2016-01-01

Little St. Germain Lake (LSG), a relatively pristine multibasin lake in Wisconsin, USA, was examined to determine how morphologic (internal), climatic (external), anthropogenic (winter aeration), and natural (beaver activity) factors affect the trophic state (phosphorus, P; chlorophyll, CHL; and Secchi depth, SD) of each of its basins. Basins intercepting the main flow and external P sources had highest P and CHL and shallowest SD. Internal loading in shallow, polymictic basins caused P and CHL to increase and SD to decrease as summer progressed. Winter aeration used to eliminate winterkill increased summer internal P loading and decreased water quality, while reductions in upstream beaver impoundments had little effect on water quality. Variations in air temperature and precipitation affected each basin differently. Warmer air temperatures increased productivity throughout the lake and decreased clarity in less eutrophic basins. Increased precipitation increased P in the basins intercepting the main flow but had little effect on the isolated deep West Bay. These relations are used to project effects of future climatic changes on LSG and other temperate lakes.

Computer simulation of the effects of shoe cushioning on internal and external loading during running impacts.

PubMed

Miller, Ross H; Hamill, Joseph

2009-08-01

Biomechanical aspects of running injuries are often inferred from external loading measurements. However, previous research has suggested that relationships between external loading and potential injury-inducing internal loads can be complex and nonintuitive. Further, the loading response to training interventions can vary widely between subjects. In this study, we use a subject-specific computer simulation approach to estimate internal and external loading of the distal tibia during the impact phase for two runners when running in shoes with different midsole cushioning parameters. The results suggest that: (1) changes in tibial loading induced by footwear are not reflected by changes in ground reaction force (GRF) magnitudes; (2) the GRF loading rate is a better surrogate measure of tibial loading and stress fracture risk than the GRF magnitude; and (3) averaging results across groups may potentially mask differential responses to training interventions between individuals.

Internalizing and externalizing problems in adolescence: general and dimension-specific effects of familial loadings and preadolescent temperament traits.

PubMed

Ormel, J; Oldehinkel, A J; Ferdinand, R F; Hartman, C A; De Winter, A F; Veenstra, R; Vollebergh, W; Minderaa, R B; Buitelaar, J K; Verhulst, F C

2005-12-01

We investigated the links between familial loading, preadolescent temperament, and internalizing and externalizing problems in adolescence, hereby distinguishing effects on maladjustment in general versus dimension-specific effects on either internalizing or externalizing problems. In a population-based sample of 2230 preadolescents (10-11 years) familial loading (parental lifetime psychopathology) and offspring temperament were assessed at baseline by parent report, and offspring psychopathology at 2.5-years follow-up by self-report, teacher report and parent report. We used purified measures of temperament and psychopathology and partialled out shared variance between internalizing and externalizing problems. Familial loading of internalizing psychopathology predicted offspring internalizing but not externalizing problems, whereas familial loading of externalizing psychopathology predicted offspring externalizing but not internalizing problems. Both familial loadings were associated with Frustration, low Effortful Control, and Fear. Frustration acted as a general risk factor predicting severity of maladjustment; low Effortful Control and Fear acted as dimension-specific risk factors that predicted a particular type of psychopathology; whereas Shyness, High-Intensity Pleasure, and Affiliation acted as direction markers that steered the conditional probability of internalizing versus externalizing problems, in the event of maladjustment. Temperament traits mediated one-third of the association between familial loading and psychopathology. Findings were robust across different composite measures of psychopathology, and applied to girls as well as boys. With regard to familial loading and temperament, it is important to distinguish general risk factors (Frustration) from dimension-specific risk factors (familial loadings, Effortful Control, Fear), and direction markers that act as pathoplastic factors (Shyness, High-Intensity Pleasure, Affiliation) from both types of risk factors. About one-third of familial loading effects on psychopathology in early adolescence are mediated by temperament.

Stress Fractures of Tibia Treated with Ilizarov External Fixator.

PubMed

Górski, Radosław; Żarek, Sławomir; Modzelewski, Piotr; Górski, Ryszard; Małdyk, Paweł

2016-08-30

Stress fractures are the result of cyclic loading of the bone, which gradually becomes damaged. Most often they are treated by rest or plaster cast and, in rare cases, by internal fixation. There is little published data on initial reposition followed by stabilization with the Ilizarov apparatus in such fractures. Six patients were treated with an external fixator according to the Ilizarov method for a stress fracture of the tibia between 2007 and 2015. Three patients were initially treated conservatively. Due to increasing tibial deformation, they were qualified for surgical treatment with external stabilization. In the other patients, surgery was the first-line treatment. All patients demonstrated risk factors for a stress fracture. After the surgery, they fully loaded the operated limb. No patient developed malunion, nonunion, infection or venous thrombosis. The average time from the first operation to the removal of the external fixator was 19 weeks. Radiographic and clinical outcomes were satisfactory in all patients. 1. The Ilizarov method allows for successful stabilization of stress fractures of the tibia. 2. It may be a good alternative to internal stabilization, especially in patients with multiple comorbidities which affect bone quality and may impair soft tissue healing.

Bungee force level, stiffness, and variation during treadmill locomotion in simulated microgravity.

PubMed

De Witt, John K; Schaffner, Grant; Ploutz-Snyder, Lori L

2014-04-01

Crewmembers performing treadmill exercise on the International Space Station must wear a harness with an external gravity replacement force that is created by elastomer bungees. The quantification of the total external force, displacement, stiffness, and force variation is important for understanding the forces applied to the crewmember during typical exercise. Data were collected during static trials in the laboratory from a single subject and four subjects were tested while walking at 1.34 m x s(-1) and running at 2.24 m x s(-1) and 3.13 m x s(-1) on a treadmill during simulated microgravity in parabolic flight. The external force was provided by bungees and carabiner clips in configurations commonly used by crewmembers. Total external force, displacement, and force variation in the bungee system were measured, from which stiffness was computed. Mean external force ranged from 431 to 804 N (54-131% bodyweight) across subjects and conditions. Mean displacement was 4 to 8 cm depending upon gait speed. Mean stiffness was affected by bungee configuration and ranged from 1.73 to 29.20 N x cm(-1). Force variation for single bungee configurations was 2.61-4.48% of total external force and between 4.30-57.5% total external force for two-bungee configurations. The external force supplied to crewmembers by elastomer bungees provided a range of loading levels with variations that occur throughout the gait cycle. The quantification of bungee-loading characteristics is important to better define the system currently used by crewmembers during exercise.

Are external knee load and EMG measures accurate indicators of internal knee contact forces during gait?

PubMed

Meyer, Andrew J; D'Lima, Darryl D; Besier, Thor F; Lloyd, David G; Colwell, Clifford W; Fregly, Benjamin J

2013-06-01

Mechanical loading is believed to be a critical factor in the development and treatment of knee osteoarthritis. However, the contact forces to which the knee articular surfaces are subjected during daily activities cannot be measured clinically. Thus, the ability to predict internal knee contact forces accurately using external measures (i.e., external knee loads and muscle electromyographic [EMG] signals) would be clinically valuable. We quantified how well external knee load and EMG measures predict internal knee contact forces during gait. A single subject with a force-measuring tibial prosthesis and post-operative valgus alignment performed four gait patterns (normal, medial thrust, walking pole, and trunk sway) to induce a wide range of external and internal knee joint loads. Linear regression analyses were performed to assess how much of the variability in internal contact forces was accounted for by variability in the external measures. Though the different gait patterns successfully induced significant changes in the external and internal quantities, changes in external measures were generally weak indicators of changes in total, medial, and lateral contact force. Our results suggest that when total contact force may be changing, caution should be exercised when inferring changes in knee contact forces based on observed changes in external knee load and EMG measures. Advances in musculoskeletal modeling methods may be needed for accurate estimation of in vivo knee contact forces. Copyright © 2012 Orthopaedic Research Society.

Career readiness and externalizing behaviors of children affected by maternal HIV/AIDS: 15-year outcomes of the PACT study.

PubMed

Murphy, Debra A; Marelich, William D; Herbeck, Diane M; Cook, Mekeila

2016-01-01

The purpose of this 15-year longitudinal study was to assess the effects of maternal HIV/AIDS on child/adolescent career readiness and externalizing behaviors. Interviews were conducted with 66 pairs of healthy children and their mothers living with HIV/AIDS (MLH), who are participants in the Parents And children Coping Together (PACT) project begun in 1997. All study participants were English or Spanish speaking. About half (48.5%) of the youth were female. Maternal health status (e.g., viral load biomedical marker, illness symptoms, physical functioning and depression) and child/adolescent outcomes (e.g., career readiness, conduct disorder, drug use, sexual behaviors, parent attachment and youth autonomy) were assessed over 20 time-points. Individual growth and GEE logistic regression models showed lower variability in maternal viral load was positively associated with better career readiness and parent attachment among adolescent/young adults. Externalizing behaviors (conduct disorder, alcohol and crystal methamphetamine use) were positively associated with maternal depression. Adolescent coping efficacy was shown to be a protective factor when applied to models on career readiness. Stability in MLH health positively affects children's career readiness over time, particularly career planning and career choices. The finding that adolescent coping efficacy may act as a protective factor against poor career planning has important implications for developing interventions to assist children in coping with parental HIV.

Career readiness and externalizing behaviors of children affected by maternal HIV/AIDS: 15-year outcomes of the PACT study

PubMed Central

Murphy, Debra A.; Marelich, William D.; Herbeck, Diane M.; Cook, Mekeila

2017-01-01

The purpose of this 15-year longitudinal study was to assess the effects of maternal HIV/AIDS on child/adolescent career readiness and externalizing behaviors. Interviews were conducted with 66 pairs of healthy children and their mothers living with HIV/AIDS (MLH), who are participants in the Parents And children Coping Together (PACT) project begun in 1997. All study participants were English or Spanish speaking. About half (48.5%) of the youth were female. Maternal health status (e.g., viral load biomedical marker, illness symptoms, physical functioning and depression) and child/adolescent outcomes (e.g., career readiness, conduct disorder, drug use, sexual behaviors, parent attachment and youth autonomy) were assessed over 20 time-points. Individual growth and GEE logistic regression models showed lower variability in maternal viral load was positively associated with better career readiness and parent attachment among adolescent/young adults. Externalizing behaviors (conduct disorder, alcohol and crystal methamphetamine use) were positively associated with maternal depression. Adolescent coping efficacy was shown to be a protective factor when applied to models on career readiness. Stability in MLH health positively affects children’s career readiness over time, particularly career planning and career choices. The finding that adolescent coping efficacy may act as a protective factor against poor career planning has important implications for developing interventions to assist children in coping with parental HIV. PMID:28983322

Loading and concurrent synchronous whole-body vibration interaction increases oxygen consumption during resistance exercise.

PubMed

Serravite, Daniel H; Edwards, David; Edwards, Elizabeth S; Gallo, Sara E; Signorile, Joseph F

2013-01-01

Exercise is commonly used as an intervention to increase caloric output and positively affect body composition. A major challenge is the low compliance often seen when the prescribed exercise is associated with high levels of exertion. Whole-body vibration (WBV) may allow increased caloric output with reduced effort; however, there is limited information concerning the effect of WBV on oxygen consumption (VO2). Therefore, this study assessed the synergistic effects of resistance training and WBV on VO2. We examined VO2 at different loads (0%, 20%, and 40% body weight (BW)) and vibration intensities (No vibration (NV), 35HZ, 2-3mm (35L), 50Hz, 57mm (50H)) in ten men (26.5 ± 5.1 years). Data were collected during different stages (rest, six 30s sets of squatting, and recovery). Repeated measures ANOVA showed a stage x load x vibration interaction. Post hoc analysis revealed no differences during rest; however, a significant vibration x load interaction occurred during exercise. Both 35L and 50H produced greater VO2 than NV at a moderate load of 20%BW. Although 40%BW produced greater VO2 than 20%BW or 0%BW using NV, no significant difference in VO2 was seen among vibratory conditions at 40%BW. Moreover, no significant differences were seen between 50H and 35L at 20%BW and NV at 40%BW. During recovery there was a main effect for load. Post hoc analyses revealed that VO2 at 40%BW was significantly higher than 20%BW or 0%BW, and 20%BW produced higher VO2 than no load. Minute-by-minute analysis revealed a significant impact on VO2 due to load but not to vibratory condition. We conclude that the synergistic effect of WBV and active squatting with a moderate load is as effective at increasing VO2 as doubling the external load during squatting without WBV. Key PointsSynchronous whole body vibration in conjunction with moderate external loading (app 20% BW) can increase oxygen consumption to the same extent as heavier loading (40% BW) during performance of the parallel squat.While the application of synchronous whole body vibration had no effect on recovery oxygen, under bot vibratory and non-vibratory conditions, the heavier the external load the greater the recovery oxygen consumption levels.Regardless of vibratory condition, during the squatting exercise bout 40% BW produced higher heart rates than 20%BW or 0% BW, and 20% BW produced higher heart rates than 0% BW.There were strong trends toward higher heart rates in both vibratory conditions (50 Hz, 5-6mm; 35 Hz, 2-3 mm) than in the non-vibratory condition regardless of external loading.

Airworthiness Qualification Criteria for Rotorcraft with External Sling Loads

NASA Technical Reports Server (NTRS)

Key, David L.

2002-01-01

This report presents the results of a study to develop airworthiness requirements for rotorcraft with external sling loads. The report starts with a review of the various phenomena that limit external sling load operations. Specifically discussed are the rotorcraft-load aeroservoelastic stability, load-on handling qualities, effects of automatic flight control system failure, load suspension system failure, and load stability at speed. Based on past experience and treatment of these phenomena, criteria are proposed to form a package for airworthiness qualification. The desired end objective is a set of operational flight envelopes for the rotorcraft with intended loads that can be provided to the user to guide operations in the field. The specific criteria proposed are parts of ADS-33E-PRF; MIL-F-9490D, and MIL-STD-913A all applied in the context of external sling loads. The study was performed for the Directorate of Engineering, U.S. Army Aviation and Missile Command (AMCOM), as part of the contract monitored by the Aerothermodynamics Directorate, U.S. Army AMCOM.

Influence of upper-body external loading on anaerobic exercise performance.

PubMed

Inacio, Mario; Dipietro, Loretta; Visek, Amanda J; Miller, Todd A

2011-04-01

The purpose of this study was to assess the threshold where simulated adipose tissue weight gain significantly affects performance in common anaerobic tasks and determine whether differences exist between men and women. Forty-six subjects (men = 21; women = 25) were tested for vertical jump, 20- and 40-yd dash, and 20-yd shuttle tests under 6 different loading conditions (0, 2, 4, 6, 8, and 10% of added body weight). Results were compared to each subject's baseline values (0% loading condition). Results demonstrate significant decrements in performance, starting at the 2% loading condition, for both genders, in every performance test (p < 0.05). On average, subjects jumped 4.91 ± 0.29 to 9.83 ± 0.30 cm less, increased agility test times from 5.49 ± 0.56 to 5.86 ± 0.61 seconds, and increased sprint times from 7.80 ± 0.96 to 8.39 ± 1.07 seconds (2-10%, respectively; p < 0.05). When lower-body power was corrected for total body mass, men exerted significantly more power than women did in every loading condition. Conversely, when lower-body power was corrected for lean body mass, men exerted significantly more power than did women only at the 2% loading condition. This study demonstrates that for the specific anaerobic performance tests performed, increases in external loading as low as 2% of body weight results in significant decreases in performance. Moreover, for these specific tests, men and women tend to express the same threshold in performance decrements.

14 CFR 133.17 - Requirements for issuance of a rotorcraft external-load operator certificate.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Requirements for issuance of a rotorcraft external-load operator certificate. 133.17 Section 133.17 Aeronautics and Space FEDERAL AVIATION... §§ 133.19, 133.21, and 133.23, the Administrator issues a Rotorcraft External-Load Operator Certificate...

14 CFR 133.17 - Requirements for issuance of a rotorcraft external-load operator certificate.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Requirements for issuance of a rotorcraft external-load operator certificate. 133.17 Section 133.17 Aeronautics and Space FEDERAL AVIATION... §§ 133.19, 133.21, and 133.23, the Administrator issues a Rotorcraft External-Load Operator Certificate...

The effect of gas and fluid flows on nonlinear lateral vibrations of rotating drill strings

NASA Astrophysics Data System (ADS)

Khajiyeva, Lelya; Kudaibergenov, Askar; Kudaibergenov, Askat

2018-06-01

In this work we develop nonlinear mathematical models describing coupled lateral vibrations of a rotating drill string under the effect of external supersonic gas and internal fluid flows. An axial compressive load and a torque also affect the drill string. The mathematical models are derived by the use of Novozhilov's nonlinear theory of elasticity with implementation of Hamilton's variation principle. Expressions for the gas flow pressure are determined according to the piston theory. The fluid flow is considered as added mass inside the curved tube of the drill string. Using an algorithm developed in the Mathematica computation program on the basis of the Galerkin approach and the stiffness switching method the numerical solution of the obtained approximate differential equations is found. Influences of the external loads, drill string angular speed of rotation, parameters of the gas and fluid flows on the drill string vibrations are shown.

Load control system. [for space shuttle external tank ground tests

NASA Technical Reports Server (NTRS)

Grosse, J. C.

1977-01-01

The load control system developed for the shuttle external structural tests is described. The system consists of a load programming/display module, and a load control module along with the following hydraulic system components: servo valves, dump valves, hydraulic system components, and servo valve manifold blocks. One load programming/display subsystem can support multiple load control subsystem modules.

Improvement of fatigue resistance for multilayer lead zirconate titanate (PZT)-based ceramic actuators by external mechanical loads

NASA Astrophysics Data System (ADS)

Yang, Gang; Yue, Zhenxing; Ji, Ye; Chu, Xiangcheng; Li, Longtu

2008-12-01

The influence of external compressive loads, applied along a direction perpendicular to polarization, on fatigue behaviors of multilayer lead zirconate titanate (PZT)-based ceramic actuators was investigated. Under no external mechanical load, a normal fatigue behavior was observed, demonstrating that both switching polarization (Pswitching) and remnant polarization (Pr) progressively decreased with increasing switching cycles due to domain pinning by charge point defects. However, an anomalous enhancement in both switching and remnant polarizations was observed upon application of the external compressive loads. After 5×106 cycles of polarization switching, Pswitching and Pr increase by about 13% and 6% at 40 MPa, respectively, while Pswitching and Pr increase by about 11% and 21% at 60 MPa, respectively. The improvement of fatigue resistance can be attributed to non-180° domain switching and suppression of microcracking, triggered by external mechanical loads.

Transformation-Induced Diffraction Peak Broadening During Bainitic and Martensitic Transformations Under Small External Loads in a Quenched and Tempered High Strength Steel

NASA Astrophysics Data System (ADS)

Dutta, R. K.; Huizenga, R. M.; Amirthalingam, M.; Hermans, M. J. M.; King, A.; Richardson, I. M.

2013-09-01

In situ phase transformation behavior of a high strength S690QL1 steel during continuous cooling under different mechanical loading conditions has been used to investigate the effect of small external loads on the transformation-induced plasticity during bainitic and martensitic transformations. The results show that during phase transformations, the untransformed austenite undergoes plastic deformation, thereby retarding further transformation to bainite/martensite. This occurs independent of external load.

Optimization of Energy Efficiency and Conservation in Green Building Design Using Duelist, Killer-Whale and Rain-Water Algorithms

NASA Astrophysics Data System (ADS)

Biyanto, T. R.; Matradji; Syamsi, M. N.; Fibrianto, H. Y.; Afdanny, N.; Rahman, A. H.; Gunawan, K. S.; Pratama, J. A. D.; Malwindasari, A.; Abdillah, A. I.; Bethiana, T. N.; Putra, Y. A.

2017-11-01

The development of green building has been growing in both design and quality. The development of green building was limited by the issue of expensive investment. Actually, green building can reduce the energy usage inside the building especially in utilization of cooling system. External load plays major role in reducing the usage of cooling system. External load is affected by type of wall sheathing, glass and roof. The proper selection of wall, type of glass and roof material are very important to reduce external load. Hence, the optimization of energy efficiency and conservation in green building design is required. Since this optimization consist of integer and non-linear equations, this problem falls into Mixed-Integer-Non-Linear-Programming (MINLP) that required global optimization technique such as stochastic optimization algorithms. In this paper the optimized variables i.e. type of glass and roof were chosen using Duelist, Killer-Whale and Rain-Water Algorithms to obtain the optimum energy and considering the minimal investment. The optimization results exhibited the single glass Planibel-G with the 3.2 mm thickness and glass wool insulation provided maximum ROI of 36.8486%, EUI reduction of 54 kWh/m2·year, CO2 emission reduction of 486.8971 tons/year and reduce investment of 4,078,905,465 IDR.

Buckling of Cracked Laminated Composite Cylindrical Shells Subjected to Combined Loading

NASA Astrophysics Data System (ADS)

Allahbakhsh, Hamidreza; Shariati, Mahmoud

2013-10-01

A series of finite element analysis on the cracked composite cylindrical shells under combined loading is carried out to study the effect of loading condition, crack size and orientation on the buckling behavior of laminated composite cylindrical shells. The interaction buckling curves of cracked laminated composite cylinders subject to different combinations of axial compression, bending, internal pressure and external pressure are obtained, using the finite element method. Results show that the internal pressure increases the critical buckling load of the CFRP cylindrical shells and bending and external pressure decrease it. Numerical analysis show that axial crack has the most detrimental effect on the buckling load of a cylindrical shell and results show that for lower values of the axial compressive load and higher values of the external pressure, the buckling is usually in the global mode and for higher values of axial compressive load and lower levels of external pressure the buckling mode is mostly in the local mode.

Does Maximal External Tibial Component Rotation Influence Tibiofemoral Load Distribution in the Primary Knee Arthroplasty Setting: A Comparison of Neutral vs Maximal Anatomical External Rotatory States.

PubMed

Manning, William A; Ghosh, Kanishka M; Blain, Alasdair P; Longstaff, Lee M; Rushton, Steven P; Deehan, David J

2017-06-01

Tibial component rotation at time of knee arthroplasty can influence conformity, load transmission across the polyethylene surface, and perhaps ultimately determined survivorship. Optimal tibial component rotation on the cut surface is reliant on standard per operative manual stressing. This subjective assessment aims to balance constraint and stability of the articulation through a full arc of movement. Using a cadaveric model, computer navigation and under defined, previously validated loaded conditions mimicking the in vivo setting, the influence of maximal tibial component external rotation compared with the neutral state was examined for changes in laxity and tibiofemoral continuous load using 3D displacement measurement and an orthosensor continuous load sensor implanted within the polyethylene spacer in a simulated single radius total knee arthroplasty. No significant difference was found throughout arc of motion (0-115 degrees of flexion) for maximal varus and/or valgus or rotatory laxity between the 2 states. The neutral state achieved equivalence for mediolateral load distribution at each point of flexion. We have found that external rotation of the tibial component increased medial compartment load in comparison with the neutral position. Compared with the neutral state, external rotation consistently effected a marginal, but not significant reduction in lateral load under similar loading conditions. The effects were most pronounced in midflexion. On the basis of these findings, we would advocate for the midtibial tubercle point to determine tibial component rotation and caution against component external rotation. Copyright © 2017 Elsevier Inc. All rights reserved.

Nectar vs. pollen loading affects the tradeoff between flight stability and maneuverability in bumblebees

PubMed Central

Mountcastle, Andrew M.; Combes, Stacey A.

2015-01-01

Bumblebee foragers spend a significant portion of their lives transporting nectar and pollen, often carrying loads equivalent to more than half their body mass. Whereas nectar is stored in the abdomen near the bee’s center of mass, pollen is carried on the hind legs, farther from the center of mass. We examine how load position changes the rotational moment of inertia in bumblebees and whether this affects their flight maneuverability and/or stability. We applied simulated pollen or nectar loads of equal mass to Bombus impatiens bumblebees and examined flight performance in a wind tunnel under three conditions: flight in unsteady flow, tracking an oscillating flower in smooth flow, and flower tracking in unsteady flow. Using an inertial model, we estimated that carrying a load on the legs rather than in the abdomen increases a bee’s moment of inertia about the roll and yaw axes but not the pitch axis. Consistent with these predictions, we found that bees carrying a load on their legs displayed slower rotations about their roll and yaw axes, regardless of whether these rotations were driven by external perturbations or self-initiated steering maneuvers. This allowed pollen-loaded bees to maintain a more stable body orientation and higher median flight speed in unsteady flow but reduced their performance when tracking a moving flower, supporting the concept of a tradeoff between stability and maneuverability. These results demonstrate that the types of resources collected by bees affect their flight performance and energetics and suggest that wind conditions may influence resource selection. PMID:26240364

Load-dependent ADP binding to myosins V and VI: Implications for subunit coordination and function

PubMed Central

Oguchi, Yusuke; Mikhailenko, Sergey V.; Ohki, Takashi; Olivares, Adrian O.; De La Cruz, Enrique M.; Ishiwata, Shin'ichi

2008-01-01

Dimeric myosins V and VI travel long distances in opposite directions along actin filaments in cells, taking multiple steps in a “hand-over-hand” fashion. The catalytic cycles of both myosins are limited by ADP dissociation, which is considered a key step in the walking mechanism of these motors. Here, we demonstrate that external loads applied to individual actomyosin V or VI bonds asymmetrically affect ADP affinity, such that ADP binds weaker under loads assisting motility. Model-based analysis reveals that forward and backward loads modulate the kinetics of ADP binding to both myosins, although the effect is less pronounced for myosin VI. ADP dissociation is modestly accelerated by forward loads and inhibited by backward loads. Loads applied in either direction slow ADP binding to myosin V but accelerate binding to myosin VI. We calculate that the intramolecular load generated during processive stepping is ≈2 pN for both myosin V and myosin VI. The distinct load dependence of ADP binding allows these motors to perform different cellular functions. PMID:18509050

Effects of formulation variables and characterization of guaifenesin wax microspheres for controlled release.

PubMed

Mani, Narasimhan; Park, M O; Jun, H W

2005-01-01

Sustained-release wax microspheres of guaifenesin, a highly water-soluble drug, were prepared by the hydrophobic congealable disperse method using a salting-out procedure. The effects of formulation variables on the loading efficiency, particle properties, and in-vitro drug release from the microspheres were determined. The type of dispersant, the amount of wetting agent, and initial stirring time used affected the loading efficiency, while the volume of external phase and emulsification speed affected the particle size of the microspheres to a greater extent. The crystal properties of the drug in the wax matrix and the morphology of the microspheres were studied by differential scanning calorimetry (DSC), powder x-ray diffraction (XRD), and scanning electron microscopy (SEM). The DSC thermograms of the microspheres showed that the drug lost its crystallinity during the microencapsulation process, which was further confirmed by the XRD data. The electron micrographs of the drug-loaded microspheres showed well-formed spherical particles with a rough exterior.

Characterization of Solid Polymers, Ceramic Gap Filler, and Closed-Cell Polymer Foam Using Low-Load Test Methods

NASA Technical Reports Server (NTRS)

Herring, Helen M.

2008-01-01

Various solid polymers, polymer-based composites, and closed-cell polymer foam are being characterized to determine their mechanical properties, using low-load test methods. The residual mechanical properties of these materials after environmental exposure or extreme usage conditions determines their value in aerospace structural applications. In this experimental study, four separate polymers were evaluated to measure their individual mechanical responses after thermal aging and moisture exposure by dynamic mechanical analysis. A ceramic gap filler, used in the gaps between the tiles on the Space Shuttle, was also tested, using dynamic mechanical analysis to determine material property limits during flight. Closed-cell polymer foam, used for the Space Shuttle External Tank insulation, was tested under low load levels to evaluate how the foam's mechanical properties are affected by various loading and unloading scenarios.

Analysis of dynamic behavior of multiple-stage planetary gear train used in wind driven generator.

PubMed

Wang, Jungang; Wang, Yong; Huo, Zhipu

2014-01-01

A dynamic model of multiple-stage planetary gear train composed of a two-stage planetary gear train and a one-stage parallel axis gear is proposed to be used in wind driven generator to analyze the influence of revolution speed and mesh error on dynamic load sharing characteristic based on the lumped parameter theory. Dynamic equation of the model is solved using numerical method to analyze the uniform load distribution of the system. It is shown that the load sharing property of the system is significantly affected by mesh error and rotational speed; load sharing coefficient and change rate of internal and external meshing of the system are of obvious difference from each other. The study provides useful theoretical guideline for the design of the multiple-stage planetary gear train of wind driven generator.

Analysis of Dynamic Behavior of Multiple-Stage Planetary Gear Train Used in Wind Driven Generator

PubMed Central

Wang, Jungang; Wang, Yong; Huo, Zhipu

2014-01-01

A dynamic model of multiple-stage planetary gear train composed of a two-stage planetary gear train and a one-stage parallel axis gear is proposed to be used in wind driven generator to analyze the influence of revolution speed and mesh error on dynamic load sharing characteristic based on the lumped parameter theory. Dynamic equation of the model is solved using numerical method to analyze the uniform load distribution of the system. It is shown that the load sharing property of the system is significantly affected by mesh error and rotational speed; load sharing coefficient and change rate of internal and external meshing of the system are of obvious difference from each other. The study provides useful theoretical guideline for the design of the multiple-stage planetary gear train of wind driven generator. PMID:24511295

Design of high precision temperature control system for TO packaged LD

NASA Astrophysics Data System (ADS)

Liang, Enji; Luo, Baoke; Zhuang, Bin; He, Zhengquan

2017-10-01

Temperature is an important factor affecting the performance of TO package LD. In order to ensure the safe and stable operation of LD, a temperature control circuit for LD based on PID technology is designed. The MAX1978 and an external PID circuit are used to form a control circuit that drives the thermoelectric cooler (TEC) to achieve control of temperature and the external load can be changed. The system circuit has low power consumption, high integration and high precision,and the circuit can achieve precise control of the LD temperature. Experiment results show that the circuit can achieve effective and stable control of the laser temperature.

Effect of Loading Efficiency on the Process of Consolidation in Unsaturated Soils

NASA Astrophysics Data System (ADS)

Lo, W. C.; Lee, J. W.; Deng, J. H.; Liu, J. H.

2016-12-01

Loading efficiency is an undrained poroelastic coefficient that causes an increase in the pore pressure due to an increase in the compressive axial stress. In order to illustrate the importance of loading efficiency on the process of consolidation in unsaturated soils, we utilize two assumptions proposed by Biot (1941) and Terzaghi (1943) to formulate the initial conditions taking account of loading efficiency and without consideration of loading efficiency, respectively. In Biot's theory (1941), he suggested that water is not allowed to escape when the external loading is instantly applied on a porous medium. Accordingly, the soil texture sample is considered to be undrained, and the linearized increment of the fluid content is equal to zero. For this reason, water and air can sustain an external loading only partially at the moment it is imposed, leading to an immediate one-dimensional consolidation. On the contrary, Terzaghi (1943) posited that as the external loading is initially applied, it is entirely sustained by the pore fluid. Thus, the initial water and air pressures are equal to the stress of external loading. Numerical calculations of excess pore water pressure and total settlement were made for a soil with clay texture as an illustrative example. A comparative study shows that in the early stage of consolidation, the model of considering loading efficiency generates larger time-dependent total settlement and also has the highest value of excess pore water pressure initially. The physical cause behind this difference is that the initial conditions established from Biot's theory is much smaller, reflecting the soil skeleton to carry most of external load at the moment it is imposed. Our results indicate that, in terms of the initial conditions for water and air pressures, the loading efficiency must be taken into account in the early stage of consolidation.

Motor unit recruitment and firing rate in medial gastrocnemius muscles during external perturbations in standing in humans.

PubMed

Pollock, C L; Ivanova, T D; Hunt, M A; Garland, S J

2014-10-01

There is limited investigation of the interaction between motor unit recruitment and rate coding for modulating force during standing or responding to external perturbations. Fifty-seven motor units were recorded from the medial gastrocnemius muscle with intramuscular electrodes in response to external perturbations in standing. Anteriorly directed perturbations were generated by applying loads in 0.45-kg increments at the pelvis every 25-40 s until 2.25 kg was maintained. Motor unit firing rate was calculated for the initial recruitment load and all subsequent loads during two epochs: 1) dynamic response to perturbation directly following each load drop and 2) maintenance of steady state between perturbations. Joint kinematics and surface electromyography (EMG) from lower extremities and force platform measurements were assessed. Application of the external loads resulted in a significant forward progression of the anterior-posterior center of pressure (AP COP) that was accompanied by modest changes in joint angles (<3°). Surface EMG increased more in medial gastrocnemius than in the other recorded muscles. At initial recruitment, motor unit firing rate immediately after the load drop was significantly lower than during subsequent load drops or during the steady state at the same load. There was a modest increase in motor unit firing rate immediately after the load drop on subsequent load drops associated with regaining balance. There was no effect of maintaining balance with increased load and forward progression of the AP COP on steady-state motor unit firing rate. The medial gastrocnemius utilized primarily motor unit recruitment to achieve the increased levels of activation necessary to maintain standing in the presence of external loads. Copyright © 2014 the American Physiological Society.

Hydrology and water quality of Delavan Lake in southeastern Wisconsin

USGS Publications Warehouse

Field, S.J.; Duerk, M.D.

1988-01-01

External loading of phosphorus and nitrogen were sufficient to cause eutrophic conditions. Internal loading of phosphorus was more than two times the external phosphorus supply. Most of the internal loading occurred when the hypolimnion was anoxic during summer. Internal loading of phosphorus during the 1985 water year was significantly reduced from that of 1984 because of a shorter anoxic period.

Radiation pattern of a borehole radar antenna

USGS Publications Warehouse

Ellefsen, K.J.; Wright, D.L.

2005-01-01

The finite-difference time-domain method was used to simulate radar waves that were generated by a transmitting antenna inside a borehole. The simulations were of four different models that included features such as a water-filled borehole and an antenna with resistive loading. For each model, radiation patterns for the far-field region were calculated. The radiation patterns show that the amplitude of the radar wave was strongly affected by its frequency, the water-filled borehole, the resistive loading of the antenna, and the external metal parts of the antenna (e.g., the cable head and the battery pack). For the models with a water-filled borehole, their normalized radiation patterns were practically identical to the normalized radiation pattern of a finite-length electric dipole when the wavelength in the formation was significantly greater than the total length of the radiating elements of the model antenna. The minimum wavelength at which this criterion was satisfied depended upon the features of the antenna, especially its external metal parts. ?? 2005 Society of Exploration Geophysicists. All rights reserved.

Tensiomyographical responses to accelerometer loads in female collegiate basketball players.

PubMed

Peterson, Kyle D; Quiggle, Gabriela T

2017-12-01

The purpose of the present study was to characterise the relationship between relative versus absolute internal and external loads in collegiate basketball players throughout the course of a season. Five Division I basketball players wore triaxial accelerometers throughout the 2015-2016 season and were tensiomyographically assessed weekly. One-way repeated-measure analysis of variance (RM ANOVA) with least-significant-difference (LSD) pairwise comparisons was used to determine which absolute weekly loads were different across the season. Cohen's d was used to supplement the determination of meaningful relative load changes. Overall RM ANOVA models suggest absolute external load differences occurred (PlayerLoad™ F = 17.63; IMA™ F = 31.63). Two-way RM ANOVA models revealed main effect differences were revealed between muscle groups for Tc (F = 9.11) and Dm (F = 3.25). Meaningful relative load changes between weeks were observed for both external and internal. The present study observed that tensiomyography utilised as a tool to monitor internal load may be more suitable for detecting fatigue from relative external load changes versus absolute load attained. Limiting weekly training volume changes to ≤10% may maintain appropriate adaptation. Mediolateral plane IMA™ and adductor longus muscle group may be pertinent metrics when monitoring female collegiate basketball athletes.

14 CFR 29.471 - General.

Code of Federal Regulations, 2011 CFR

2011-01-01

... equilibrium. For limit ground loads— (1) The limit ground loads obtained in the landing conditions in this part must be considered to be external loads that would occur in the rotorcraft structure if it were acting as a rigid body; and (2) In each specified landing condition, the external loads must be placed in...

Changes in In Vivo Knee Loading with a Variable-Stiffness Intervention Shoe Correlate with Changes in the Knee Adduction Moment

PubMed Central

Erhart, Jennifer C.; Dyrby, Chris O.; D'Lima, Darryl D.; Colwell, Clifford W.; Andriacchi, Thomas P.

2010-01-01

External knee adduction moment can be reduced using footwear interventions, but the exact changes in in vivo medial joint loading remain unknown. An instrumented knee replacement was used to assess changes in in vivo medial joint loading in a single patient walking with a variable-stiffness intervention shoe. We hypothesized that during walking with a load modifying variable-stiffness shoe intervention: (1) the first peak knee adduction moment will be reduced compared to a subject's personal shoes; (2) the first peak in vivo medial contact force will be reduced compared to personal shoes; and (3) the reduction in knee adduction moment will be correlated with the reduction in medial contact force. The instrumentation included a motion capture system, force plate, and the instrumented knee prosthesis. The intervention shoe reduced the first peak knee adduction moment (13.3%, p=0.011) and medial compartment joint contact force (22%; p=0.008) compared to the personal shoe. The change in first peak knee adduction moment was significantly correlated with the change in first peak medial contact force (R2=0.67, p=0.007). Thus, for a single subject with a total knee prosthesis the variable-stiffness shoe reduces loading on the affected compartment of the joint. The reductions in the external knee adduction moment are indicative of reductions in in vivo medial compressive force with this intervention. PMID:20973058

Numerical Modelling and Analysis of Hydrostatic Thrust Air Bearings for High Loading Capacities and Low Air Consumption

NASA Astrophysics Data System (ADS)

Yu, Yunluo; Pu, Guang; Jiang, Kyle

2017-12-01

The paper presents a numerical simulation study on hydrostatic thrust air bearings to assess the load capacity, compressed air consumptions, and the dynamic response. Finite Difference Method (FDM) and Finite Volume Method (FVM) are combined to solve the non-linear Reynolds equation to find the pressure distribution of the air bearing gas film and the total loading capacity of the bearing. The influence of design parameters on air film gap characteristics, including the air film thickness, supplied pressure, depth of the groove and external load, are investigated based on the proposed FDM model. The simulation results show that the thrust air bearings with a groove have a higher load capacity and air consumption than without a groove, and the load capacity and air consumption both increase with the depth of the groove. Bearings without the groove are better damped than those with the grooves, and the stability of thrust bearing decreases when the groove depth increases. The stability of the thrust bearings is also affected by their loading.

A Predictive Model for Chemically-Induced Fracture

NASA Astrophysics Data System (ADS)

Carter, Emily

2004-03-01

Mechanical properties of bulk solids are affected not only by macroscopic external loads, but also by chemical reactions, typically at surfaces and interfaces. For example, impurities in metals often coalesce at grain boundaries, leading to weakening of the sample under stress. Atmospheric corrosion is another example that, when combined with external loads, leads to stress-corrosion cracking. These are inherently multiscale phenomena, where the chemistry occurring at the atomic scale profoundly affects the mechanical properties at the micron to millimeter scale. Here we discuss a multiscale model of environmentally-assisted fracture. This involves coupling periodic density functional theory (DFT) at the atomic scale to a finite element continuum mechanics description of the coarser scale. A key component is the cohesive law, which we have shown takes on a universal form distinct from the generally used UBER model. Further, we propose a scheme to calculate physically realistic cohesive laws in the presence of mobile impurities. This cohesive law is then used to in a continuum model that couples stress-assisted diffusion with cohesive zone models of fracture to describe hydrogen embrittlement in metals. We show that this model, with a first principles-based cohesive law, provides insight into the observed intermittent cracking in steel, as well as good quantitative agreement with experiment.

The Influence of Load and Speed on Individuals' Movement Behavior.

PubMed

Frost, David M; Beach, Tyson A C; Callaghan, Jack P; McGill, Stuart M

2015-09-01

Because individuals' movement patterns have been linked to their risk of future injury, movement evaluations have become a topic of interest. However, if individuals adapt their movement behavior in response to the demands of a task, the utility of evaluations comprising only low-demand activities could have limited application with regard to the prediction of future injury. This investigation examined the impact of load and speed on individuals' movement behavior. Fifty-two firefighters performed 5 low-demand (i.e., light load, low movement speed) whole-body tasks (i.e., lift, squat, lunge, push, and pull). Each task was then modified by increasing the speed, external load, or speed and load. Select measures of motion were used to characterize the performance of each task, and comparisons were made between conditions. The participants adapted their movement behavior in response to the external demands of a task (64 and 70% of all the variables were influenced [p ≤ 0.05] by changing the load and speed, respectively), but in a manner unique to the task and type of demand. The participants exhibited greater spine and frontal plane knee motion in response to an increase in speed when compared with increasing loads. However, there were a large number of movement strategies exhibited by individual firefighters that differed from the group's response. The data obtained here imply that individuals may not be physically prepared to perform safely or effectively when a task's demands are elevated simply because they exhibit the ability to perform a low-demand activity with competence. Therefore, movement screens comprising only low-demand activities may not adequately reflect an individual's capacity, or their risk of injury, and could adversely affect any recommendations that are made for training or job performance.

Relationships Between Results Of An Internal And External Match Load Determining Method In Male, Singles Badminton Players.

PubMed

Abdullahi, Yahaya; Coetzee, Ben; Van den Berg, Linda

2017-07-03

The study purpose was to determine relationships between results of internal and external match load determining methods. Twenty-one players, who participated in selected badminton championships during the 2014/2015 season served as subjects. The heart rate (HR) values and GPS data of each player were obtained via a fix Polar HR Transmitter Belt and MinimaxX GPS device. Moderate significant Spearman's rank correlations were found between HR and absolute duration (r = 0.43 at a low intensity (LI) and 0.44 at a high intensity (HI)), distance covered (r = 0.42 at a HI) and player load (PL) (r = 0.44 at a HI). Results also revealed an opposite trend for external and internal measures of load as the average relative HR value was found to be the highest for the HI zone (54.1%) compared to the relative measures of external load where average values (1.29-9.89%) were the lowest for the HI zone. In conclusion, our findings show that results of an internal and external badminton match load determining method are more related to each other in the HI zone than other zones and that the strength of relationships depend on the duration of activities that are performed in especially LI and HI zones. Overall, trivial to moderate relationships between results of an internal and external match load determining method in male, singles badminton players reaffirm the conclusions of others that these constructs measure distinctly different demands and should therefore be measured concurrently to fully understand the true requirements of badminton match play.

Monitoring external and internal loads of brazilian soccer referees during official matches.

PubMed

Costa, Eduardo C; Vieira, Caio M A; Moreira, Alexandre; Ugrinowitsch, Carlos; Castagna, Carlo; Aoki, Marcelo S

2013-01-01

This study aimed to assess the external and internal loads of Brazilian soccer referees during official matches. A total of 11 field referees (aged 36.2 ± 7.5 years) were monitored during 35 matches. The external (distance covered, mean and maximal speed) and internal load parameters (session ratings of perceived exertion [RPE] training load [TL], Edwards' TL, and time spent in different heart rate [HR] zones) were assessed in 3-4 matches per referee. External load parameters were measured using a wrist Global Positioning System (GPS) receiver. No differences in distance covered (5.219 ± 205 vs. 5.230 ± 237 m) and maximal speed (19.3 ± 1.0 vs. 19.4 ± 1.4 km·h(-1)) were observed between the halves of the matches (p > 0.05). However, the mean speed was higher in the first half of the matches (6.6 ± 0.4 vs. 6.4 ± 0.3 km·h(-1)) (p < 0.05) than in the second half. The mean HR during the matches was ~89% of HRmax. In ~95% of the matches, the referees demonstrated a HR ≥ 80% of HRmax. Nonetheless, the time spent at 90-100% of HRmax was higher in the first half (59.9 vs. 52.3%) (p < 0.05). Significant correlations between session RPE TL and distance covered at 90-100% of HRmax (r = 0.62) and session RPE TL and maximal speed (r = 0.54) (p < 0.05) were noted. Furthermore, there was a positive correlation between session RPE TL and Edwards' TL (r = 0.61) (p < 0.05). Brazilian soccer referees demonstrated high external and internal load demands during official matches. The portable GPS/HR monitors and session RPE method can provide relevant information regarding the magnitude of the physiological strain during official matches. Key PointsHigh external and internal loads were imposed on Brazilian soccer referees during official matches.There was a high positive correlation between a subjective marker of internal load (session RPE) and parameters of external load (distance covered between 90-100% of HRmax and maximal speed).There was a high positive correlation between session RPE method and Edwards' method.Session RPE seems to be a reliable marker of internal load.The portable GPS/HR monitors and the session RPE method can provide relevant information regarding the magnitude of external and internal loads of soccer referees during official matches.

Muscle Activation Differs Between Partial and Full Back Squat Exercise With External Load Equated.

PubMed

da Silva, Josinaldo J; Schoenfeld, Brad J; Marchetti, Priscyla N; Pecoraro, Silvio L; Greve, Julia M D; Marchetti, Paulo H

2017-06-01

Changes in range of motion affect the magnitude of the load during the squat exercise and, consequently, may influence muscle activation. The purpose of this study was to evaluate muscle activation between the partial and full back squat exercise with external load equated on a relative basis between conditions. Fifteen young, healthy, resistance-trained men (age: 26 ± 5 years, height: 173 ± 6 cm) performed a back squat at their 10 repetition maximum (10RM) using 2 different ranges of motion (partial and full) in a randomized, counterbalanced fashion. Surface electromyography was used to measure muscle activation of the vastus lateralis, vastus medialis, rectus femoris, biceps femoris (BF), semitendinosus, erector spinae, soleus (SL), and gluteus maximus (GM). In general, muscle activity was highest during the partial back squat for GM (p = 0.004), BF (p = 0.009), and SL (p = 0.031) when compared with full-back squat. There was no significant difference for rating of perceived exertion between partial and full back squat exercise at 10RM (8 ± 1 and 9 ± 1, respectively). In conclusion, the range of motion in the back squat alters muscle activation of the prime mover (GM) and stabilizers (SL and BF) when performed with the load equated on a relative basis. Thus, the partial back squat maximizes the level of muscle activation of the GM and associated stabilizer muscles.

Development of Handling Qualities Criteria for Rotorcraft with Externally Slung Loads

NASA Technical Reports Server (NTRS)

Hoh, Roger H.; Heffley, Robert K.; Mitchell, David G.

2006-01-01

Piloted simulations were performed on the NASA-Ames Vertical Motion Simulator (VMS) to explore handling qualities issues for large cargo helicopters, particularly focusing on external slung load operations. The purpose of this work was based upon the need to include handling qualities criteria for cargo helicopters in an upgrade to the U.S. Army's rotorcraft handling qualities specification, Aeronautical Design Standard-33 (ADS-33E-PRF). From the VMS results, handling qualities criteria were developed fro cargo helicopters carrying external slung loads in the degraded visual environment (DVE). If satisfied, these criteria provide assurance that the handling quality rating (HQR) will be 4 or better for operations in the DVE, and with a load mass ratio of 0.33 or less. For lighter loads, flying qualities were found to be less dependent on the load geometry and therefore the significance of the criteria is less. For heavier loads, meeting the criteria ensures the best possible handling qualities, albeit Level 2 for load mass ratios greater than 0.33.

Upper limb load as a function of repetitive task parameters: part 1--a model of upper limb load.

PubMed

Roman-Liu, Danuta

2005-01-01

The aim of the study was to develop a theoretical indicator of upper limb musculoskeletal load based on repetitive task parameters. As such the dimensionless parameter, Integrated Cycle Load (ICL) was accepted. It expresses upper limb load which occurs during 1 cycle. The indicator is based on a model of a repetitive task, which consists of a model of the upper limb, a model of basic types of upper limb forces and a model of parameters of a repetitive task such as length of the cycle, length of periods of the cycle and external force exerted during each of the periods of the cycle. Calculations of the ICL parameter were performed for 12 different variants of external load characterised by different values of repetitive task parameters. A comparison of ICL, which expresses external load with a physiological indicator of upper limb load, is presented in Part 2 of the paper.

The use of 3d scanner for testing changes in shape of human limbs under the influence of external mechanical load

NASA Astrophysics Data System (ADS)

Kasperska, Kamila; Wieczorowski, Michał; Krolczyk, Jolanta B.

2017-10-01

Three-dimensional scanning is used in many fields: medicine, architecture, industry, reverse engineering. The aim of the article was to analyze the changes in the shape of the limbs under the influence of a mechanical external load using the method of three-dimensional scanner uses white light technology. The paper presents a system of human movement, passive part - skeleton and active part - the muscles, and principles of their interaction, which results in a change of the position of the body. Furthermore, by using the 3D scan, the differences in appearance of the arm and leg depending on the size of the external load in different positions have been presented. The paper shows that with increasing load, which muscles must prevent, increases the volume of certain parts of the legs, while another parts of them will be reduced. Results of the research using three-dimensional scanner allow determining what impact on changing the legs shape has an external mechanical load.

The impact of cognitive control, incentives, and working memory load on the P3 responses of externalizing prisoners.

PubMed

Baskin-Sommers, Arielle R; Krusemark, Elizabeth A; Curtin, John J; Lee, Christopher; Vujnovich, Aleice; Newman, Joseph P

2014-02-01

The P3 amplitude reduction is one of the most common correlates of externalizing. However, few studies have used experimental manipulations designed to challenge different cognitive functions in order to clarify the processes that impact this reduction. To examine factors moderating P3 amplitude in trait externalizing, we administered an n-back task that manipulated cognitive control demands, working memory load, and incentives to a sample of male offenders. Offenders with high trait externalizing scores did not display a global reduction in P3 amplitude. Rather, the negative association between trait externalizing and P3 amplitude was specific to trials involving inhibition of a dominant response during infrequent stimuli, in the context of low working memory load, and incentives for performance. In addition, we discuss the potential implications of these findings for externalizing-related psychopathologies. The results complement and expand previous work on the process-level dysfunction contributing to externalizing-related deficits in P3. Copyright © 2013 Elsevier B.V. All rights reserved.

Load-dependent assembly of the bacterial flagellar motor.

PubMed

Tipping, Murray J; Delalez, Nicolas J; Lim, Ren; Berry, Richard M; Armitage, Judith P

2013-08-20

It is becoming clear that the bacterial flagellar motor output is important not only for bacterial locomotion but also for mediating the transition from liquid to surface living. The output of the flagellar motor changes with the mechanical load placed on it by the external environment: at a higher load, the motor runs more slowly and produces higher torque. Here we show that the number of torque-generating units bound to the flagellar motor also depends on the external mechanical load, with fewer stators at lower loads. Stalled motors contained at least as many stators as rotating motors at high load, indicating that rotation is unnecessary for stator binding. Mutant stators incapable of generating torque could not be detected around the motor. We speculate that a component of the bacterial flagellar motor senses external load and mediates the strength of stator binding to the rest of the motor. The transition between liquid living and surface living is important in the life cycles of many bacteria. In this paper, we describe how the flagellar motor, used by bacteria for locomotion through liquid media and across solid surfaces, is capable of adjusting the number of bound stator units to better suit the external load conditions. By stalling motors using external magnetic fields, we also show that rotation is not required for maintenance of stators around the motor; instead, torque production is the essential factor for motor stability. These new results, in addition to previous data, lead us to hypothesize that the motor stators function as mechanosensors as well as functioning as torque-generating units.

Fifteen-year study of environmental dredging effect on variation of nitrogen and phosphorus exchange across the sediment-water interface of an urban lake.

PubMed

Liu, Cheng; Zhong, Jicheng; Wang, Jianjun; Zhang, Lu; Fan, Chengxin

2016-12-01

Environmental dredging has been applied widely in Chinese lakes to reduce their internal nutrient loads. However, the efficacy of dredging to reduce internal loading of nitrogen (N) and phosphorus (P) and to improve water quality has been questioned by some researchers. In this study, the long-term (∼15 years) effects of dredging to reduce internal N and P loading in a closed, polluted urban lake were investigated. The results showed that the release of soluble reactive phosphorus (SRP) could be suppressed quickly after dredging, and that the dredging effect was sustained for about 18 months. A significant release of NH 4 + -N was discovered during the first 2-8 months after dredging, followed by maintenance of low-level release rates for about 21-32 months. The continuous inflowing of external pollution loading led to the increase in the release rates of SRP and NH 4 + -N. The external pollution loading was therefore reduced three years after dredging to strengthen the remediation effect. After that, high diffusive flux from the sediment was observed for both NH 4 + -N and SRP during summer seasons for about six years, followed by a decreasing trend. The NH 4 + -N concentration in the overlying water was reduced after the reduction of external loading, while a high concentration of SRP in the overlying water was still observed during summer seasons. In conclusion, the mid-term (<3 years) reduction of internal N and P loading could be achieved by dredging if the external pollution loading were not reduced. Achieving long-term control would require modification of external loading. Copyright © 2016 Elsevier Ltd. All rights reserved.

14 CFR 23.301 - Loads.

Code of Federal Regulations, 2010 CFR

2010-01-01

... load would significantly change the distribution of external or internal loads, this redistribution...) and ultimate loads (limit loads multiplied by prescribed factors of safety). Unless otherwise provided...

Internal ecosystem feedbacks enhance nitrogen-fixing cyanobacteria blooms and complicate management in the Baltic Sea.

PubMed

Vahtera, Emil; Conley, Daniel J; Gustafsson, Bo G; Kuosa, Harri; Pitkänen, Heikki; Savchuk, Oleg P; Tamminen, Timo; Viitasalo, Markku; Voss, Maren; Wasmund, Norbert; Wulff, Fredrik

2007-04-01

Eutrophication of the Baltic Sea has potentially increased the frequency and magnitude of cyanobacteria blooms. Eutrophication leads to increased sedimentation of organic material, increasing the extent of anoxic bottoms and subsequently increasing the internal phosphorus loading. In addition, the hypoxic water volume displays a negative relationship with the total dissolved inorganic nitrogen pool, suggesting greater overall nitrogen removal with increased hypoxia. Enhanced internal loading of phosphorus and the removal of dissolved inorganic nitrogen leads to lower nitrogen to phosphorus ratios, which are one of the main factors promoting nitrogenfixing cyanobacteria blooms. Because cyanobacteria blooms in the open waters of the Baltic Sea seem to be strongly regulated by internal processes, the effects of external nutrient reductions are scale-dependent. During longer time scales, reductions in external phosphorus load may reduce cyanobacteria blooms; however, on shorter time scales the internal phosphorus loading can counteract external phosphorus reductions. The coupled processes inducing internal loading, nitrogen removal, and the prevalence of nitrogen-fixing cyanobacteria can qualitatively be described as a potentially self-sustaining "vicious circle." To effectively reduce cyanobacteria blooms and overall signs of eutrophication, reductions in both nitrogen and phosphorus external loads appear essential.

The Implications of Reduced Ground Reaction Forces During Space Flight for Bone Strains

NASA Technical Reports Server (NTRS)

Peterman, Marc M.; Hamel, Andrew J.; Sharkey, Neil A.; Piazza, Stephen J.; Cavanagh, Peter R.

1998-01-01

The specific mechanisms regulating bone mass are not known, but most investigators agree that bone maintenance is largely dependent upon mechanical demand and the resultant local bone strains. During space flight, bone loss such as that reported by LeBlanc et al. may result from failure to effectively load the skeleton and generate sufficient localized bone strains. In microgravity, a gravity replacement system can be used to tether an exercising subject to a treadmill. It follows that the ability to prevent bone loss is critically dependent upon the external ground reaction forces (GRFs) and skeletal loads imparted by the tethering system. To our knowledge, the loads during orbital flight have been measured only once (on STS 81). Based on these data and data from ground based experiments, it appears likely that interventions designed to prevent bone loss in micro-gravity generate GRFs substantially less than body weight. It is unknown to what degree reductions in external GRFs will affect internal bone strain and thus the bone maintenance response. To better predict the efficacy of treadmill exercise in micro-gravity we used a unique cadaver model to measure localized bone strains under conditions representative of those that might be produced by a gravity replacement system in space.

Biomechanical evaluation of an innovative spring-loaded axillary crutch design.

PubMed

Zhang, Yanxin; Liu, Guangyu; Xie, Shengquan; Liger, Aurélien

2011-01-01

We evaluated an innovative spring-loaded crutch design by comparing its performance with standard crutches through a biomechanical approach. Gait analysis was conducted for 7 male subjects under two conditions: walking with standard crutches and with spring-loaded crutches. Three-dimensional kinematic data and ground reaction force were recorded. Spatiotemporal variables, external mechanical work, and elastic energy (for spring crutches) were calculated based on recorded data. The trajectories of vertical ground reaction forces with standard crutches had two main peaks before and after mid-stance, and those with optimized spring-loaded crutches had only one main peak. The magnitude of external mechanical work was significantly higher with spring-loaded crutches than with standard crutches for all subjects, and the transferred elastic energy made an important contribution to the total external work for spring-loaded crutches. No significant differences in the spatiotemporal parameters were observed. Optimized spring-loaded crutches can efficiently propel crutch walkers and could reduce the total energy expenditure in crutch walking. Further research using optimized spring-loaded crutches with respect to energy efficiency is recommended.

Effects of External Loads on Human Head Movement Control Systems

NASA Technical Reports Server (NTRS)

Nam, M. H.; Choi, O. M.

1984-01-01

The central and reflexive control strategies underlying movements were elucidated by studying the effects of external loads on human head movement control systems. Some experimental results are presented on dynamic changes weigh the addition of aviation helmet (SPH4) and lead weights (6 kg). Intended time-optimal movements, their dynamics and electromyographic activity of neck muscles in normal movements, and also in movements made with external weights applied to the head were measured. It was observed that, when the external loads were added, the subject went through complex adapting processes and the head movement trajectory and its derivatives reached steady conditions only after transient adapting period. The steady adapted state was reached after 15 to 20 seconds (i.e., 5 to 6 movements).

In vitro modeling of human tibial strains during exercise in micro-gravity

NASA Technical Reports Server (NTRS)

Peterman, M. M.; Hamel, A. J.; Cavanagh, P. R.; Piazza, S. J.; Sharkey, N. A.

2001-01-01

Prolonged exposure to micro-gravity causes substantial bone loss (Leblanc et al., Journal of Bone Mineral Research 11 (1996) S323) and treadmill exercise under gravity replacement loads (GRLs) has been advocated as a countermeasure. To date, the magnitudes of GRLs employed for locomotion in space have been substantially less than the loads imposed in the earthbound 1G environment, which may account for the poor performance of locomotion as an intervention. The success of future treadmill interventions will likely require GRLs of greater magnitude. It is widely held that mechanical tissue strain is an important intermediary signal in the transduction pathway linking the external loading environment to bone maintenance and functional adaptation; yet, to our knowledge, no data exist linking alterations in external skeletal loading to alterations in bone strain. In this preliminary study, we used unique cadaver simulations of micro-gravity locomotion to determine relationships between localized tibial bone strains and external loading as a means to better predict the efficacy of future exercise interventions proposed for bone maintenance on orbit. Bone strain magnitudes in the distal tibia were found to be linearly related to ground reaction force magnitude (R(2)>0.7). Strain distributions indicated that the primary mode of tibial loading was in bending, with little variation in the neutral axis over the stance phase of gait. The greatest strains, as well as the greatest strain sensitivity to altered external loading, occurred within the anterior crest and posterior aspect of the tibia, the sites furthest removed from the neutral axis of bending. We established a technique for estimating local strain magnitudes from external loads, and equations for predicting strain during simulated micro-gravity walking are presented.

Flight Testing and Real-Time System Identification Analysis of a UH-60A Black Hawk Helicopter with an Instrumented External Sling Load

NASA Technical Reports Server (NTRS)

McCoy, Allen H.

1998-01-01

Helicopter external air transportation plays an important role in today's world. For both military and civilian helicopters, external sling load operations offer an efficient and expedient method of handling heavy, oversized cargo. With the ability to reach areas otherwise inaccessible by ground transportation, helicopter external load operations are conducted in industries such as logging, construction, and fire fighting, as well as in support of military tactical transport missions. Historically, helicopter and load combinations have been qualified through flight testing, requiring considerable time and cost. With advancements in simulation and flight test techniques there is potential to substantially reduce costs and increase the safety of helicopter sling load certification. Validated simulation tools make possible accurate prediction of operational flight characteristics before initial flight tests. Real time analysis of test data improves the safety and efficiency of the testing programs. To advance these concepts, the U.S. Army and NASA, in cooperation with the Israeli Air Force and Technion, under a Memorandum of Agreement, seek to develop and validate a numerical model of the UH-60 with sling load and demonstrate a method of near real time flight test analysis. This thesis presents results from flight tests of a U.S. Army Black Hawk helicopter with various external loads. Tests were conducted as the U.S. first phase of this MOA task. The primary load was a container express box (CONEX) which contained a compact instrumentation package. The flights covered the airspeed range from hover to 70 knots. Primary maneuvers were pitch and roll frequency sweeps, steps, and doublets. Results of the test determined the effect of the suspended load on both the aircraft's handling qualities and its control system's stability margins. Included were calculations of the stability characteristics of the load's pendular motion. Utilizing CIFER(R) software, a method for near-real time system identification was also demonstrated during the flight test program.

Pathological gait in children with Legg-Calvé-Perthes disease and proposal for gait modification to decrease the hip joint loading.

PubMed

Svehlík, Martin; Kraus, Tanja; Steinwender, Gerhard; Zwick, Ernst B; Linhart, Wolfgang E

2012-06-01

Legg-Calvé-Perthes disease (LCP) severely limits the range of hip motion and hinders a normal gait. Loading of the hip joint is a major consideration in LCP treatment. The aim of this study was to evaluate gait patterns in LCP and identify gait modifications to decrease the load on the affected hip. Forty children with unilateral LCP were divided into three groups based on the time base integral of the hip abductor moments during single stance on the affected side acquired during instrumented 3D gait analysis. X-rays of the affected hip were classified according to Herring and Catterall. Children in the "unloading" group spontaneously adopted a Duchenne-like gait with pelvis elevation, hip abduction and external rotation during single support phase. The "normal-loading" group showed pelvis elevation with a neutral hip position in the frontal plane. In the "overloading" group the pelvis dropped to the swinging limb at the beginning of stance accompanied by prolonged hip adduction. The time base integral of the hip abductor moments during single stance correlated positively with the X-ray classifications of Herring and Catterall, hip abduction angle and age. Older children preferred to walk in hip adduction during single stance, had more impaired hips and tended to overload them. The hip overloading pattern should be avoided in children with LCP. Gait training to unload the hip might become an integral component of conservative treatment in children with LCP.

Euler Strut: A Mechanical Analogy for Dynamics in the Vicinity of a Critical Point

ERIC Educational Resources Information Center

Bobnar, Jaka; Susman, Katarina; Parsegian, V. Adrian; Rand, Peter R.; Cepic, Mojca; Podgornik, Rudolf

2011-01-01

An anchored elastic filament (Euler strut) under an external point load applied to its free end is a simple model for a second-order phase transition. In the static case, a load greater than the critical load causes a Euler buckling instability, leading to a change in the filament's shape. The analysis of filament dynamics with an external point…

Nonlinear dynamic analysis of cantilevered piezoelectric energy harvesters under simultaneous parametric and external excitations

NASA Astrophysics Data System (ADS)

Fang, Fei; Xia, Guanghui; Wang, Jianguo

2018-02-01

The nonlinear dynamics of cantilevered piezoelectric beams is investigated under simultaneous parametric and external excitations. The beam is composed of a substrate and two piezoelectric layers and assumed as an Euler-Bernoulli model with inextensible deformation. A nonlinear distributed parameter model of cantilevered piezoelectric energy harvesters is proposed using the generalized Hamilton's principle. The proposed model includes geometric and inertia nonlinearity, but neglects the material nonlinearity. Using the Galerkin decomposition method and harmonic balance method, analytical expressions of the frequency-response curves are presented when the first bending mode of the beam plays a dominant role. Using these expressions, we investigate the effects of the damping, load resistance, electromechanical coupling, and excitation amplitude on the frequency-response curves. We also study the difference between the nonlinear lumped-parameter and distributed-parameter model for predicting the performance of the energy harvesting system. Only in the case of parametric excitation, we demonstrate that the energy harvesting system has an initiation excitation threshold below which no energy can be harvested. We also illustrate that the damping and load resistance affect the initiation excitation threshold.

Nonlinear dynamic analysis of cantilevered piezoelectric energy harvesters under simultaneous parametric and external excitations

NASA Astrophysics Data System (ADS)

Fang, Fei; Xia, Guanghui; Wang, Jianguo

2018-06-01

The nonlinear dynamics of cantilevered piezoelectric beams is investigated under simultaneous parametric and external excitations. The beam is composed of a substrate and two piezoelectric layers and assumed as an Euler-Bernoulli model with inextensible deformation. A nonlinear distributed parameter model of cantilevered piezoelectric energy harvesters is proposed using the generalized Hamilton's principle. The proposed model includes geometric and inertia nonlinearity, but neglects the material nonlinearity. Using the Galerkin decomposition method and harmonic balance method, analytical expressions of the frequency-response curves are presented when the first bending mode of the beam plays a dominant role. Using these expressions, we investigate the effects of the damping, load resistance, electromechanical coupling, and excitation amplitude on the frequency-response curves. We also study the difference between the nonlinear lumped-parameter and distributed-parameter model for predicting the performance of the energy harvesting system. Only in the case of parametric excitation, we demonstrate that the energy harvesting system has an initiation excitation threshold below which no energy can be harvested. We also illustrate that the damping and load resistance affect the initiation excitation threshold.

The Relationships Between Internal and External Measures of Training Load and Intensity in Team Sports: A Meta-Analysis.

PubMed

McLaren, Shaun J; Macpherson, Tom W; Coutts, Aaron J; Hurst, Christopher; Spears, Iain R; Weston, Matthew

2018-03-01

The associations between internal and external measures of training load and intensity are important in understanding the training process and the validity of specific internal measures. We aimed to provide meta-analytic estimates of the relationships, as determined by a correlation coefficient, between internal and external measures of load and intensity during team-sport training and competition. A further aim was to examine the moderating effects of training mode on these relationships. We searched six electronic databases (Scopus, Web of Science, PubMed, MEDLINE, SPORTDiscus, CINAHL) for original research articles published up to September 2017. A Boolean search phrase was created to include search terms relevant to team-sport athletes (population; 37 keywords), internal load (dependent variable; 35 keywords), and external load (independent variable; 81 keywords). Articles were considered for meta-analysis when a correlation coefficient describing the association between at least one internal and one external measure of session load or intensity, measured in the time or frequency domain, was obtained from team-sport athletes during normal training or match-play (i.e., unstructured observational study). The final data sample included 122 estimates from 13 independent studies describing 15 unique relationships between three internal and nine external measures of load and intensity. This sample included 295 athletes and 10,418 individual session observations. Internal measures were session ratings of perceived exertion (sRPE), sRPE training load (sRPE-TL), and heart-rate-derived training impulse (TRIMP). External measures were total distance (TD), the distance covered at high and very high speeds (HSRD ≥ 13.1-15.0 km h -1 and VHSRD ≥ 16.9-19.8 km h -1 , respectively), accelerometer load (AL), and the number of sustained impacts (Impacts > 2-5 G). Distinct training modes were identified as either mixed (reference condition), skills, metabolic, or neuromuscular. Separate random effects meta-analyses were conducted for each dataset (n = 15) to determine the pooled relationships between internal and external measures of load and intensity. The moderating effects of training mode were examined using random-effects meta-regression for datasets with at least ten estimates (n = 4). Magnitude-based inferences were used to interpret analyses outcomes. During all training modes combined, the external load relationships for sRPE-TL were possibly very large with TD [r = 0.79; 90% confidence interval (CI) 0.74 to 0.83], possibly large with AL (r = 0.63; 90% CI 0.54 to 0.70) and Impacts (r = 0.57; 90% CI 0.47 to 0.64), and likely moderate with HSRD (r = 0.47; 90% CI 0.32 to 0.59). The relationship between TRIMP and AL was possibly large (r = 0.54; 90% CI 0.40 to 0.66). All other relationships were unclear or not possible to infer (r range 0.17-0.74, n = 10 datasets). Between-estimate heterogeneity [standard deviations (SDs) representing unexplained variation; τ] in the pooled internal-external relationships were trivial to extremely large for sRPE (τ range = 0.00-0.47), small to large for sRPE-TL (τ range = 0.07-0.31), and trivial to moderate for TRIMP (τ range= 0.00-0.17). The internal-external load relationships during mixed training were possibly very large for sRPE-TL with TD (r = 0.82; 90% CI 0.75 to 0.87) and AL (r = 0.81; 90% CI 0.74 to 0.86), and TRIMP with AL (r = 0.72; 90% CI 0.55 to 0.84), and possibly large for sRPE-TL with HSRD (r = 0.65; 90% CI 0.44 to 0.80). A reduction in these correlation magnitudes was evident for all other training modes (range of the change in r when compared with mixed training - 0.08 to - 0.58), with these differences being unclear to possibly large. Training mode explained 24-100% of the between-estimate variance in the internal-external load relationships. Measures of internal load derived from perceived exertion and heart rate show consistently positive associations with running- and accelerometer-derived external loads and intensity during team-sport training and competition, but the magnitude and uncertainty of these relationships are measure and training mode dependent.

Preparation of hemoglobin-loaded nano-sized particles with porous structure as oxygen carriers.

PubMed

Zhao, Jian; Liu, Chang-Sheng; Yuan, Yuan; Tao, Xin-Yi; Shan, Xiao-Qian; Sheng, Yan; Wu, Fan

2007-03-01

Hb (hemoglobin)-loaded particles (HbP) encapsulated by a biodegradable polymer used as oxygen carrier were prepared. A modified double emulsion and solvent diffusion/evaporation method was adopted. All experiments were performed based on two types of biodegradable polymers, poly(epsilon-caprolactone) (PCL) and poly(epsilon-caprolactone-ethylene glycol) (PCL-PEG). The biodistribution and the survival time in blood of the particles were investigated in a mouse model. Encapsulation efficiency and pore-connecting efficiency were evaluated by a novel sulfocyanate potassium method. The influence of process parameters on the particle size and pore-connecting efficiency (PCE%) of nanoparticles have been discussed. The prepared conditions: solvent, external aqueous phase, pressure were discussed. The system utilizing dichloromethane (DCM)/ethyl acetate (EA) as a solvent with an unsaturated external aqueous phase yielded the highest encapsulation efficiency (87.35%) with a small mean particle size (153 nm). The formation of porous channels was attributed to the diffusion of solvent. The PCE% was more sensitive to the rate of solvent diffusion that was obviously affected by the preparation temperature. The PCE% reached 87.47% when PCL-PEG was employed at 25 degrees C. P(50) of HbP was 27 mmHg, which does not seem to be greatly affected by the encapsulation procedure. In vivo, following intravenous injection of 6-coumarin labeled HbP, the major organ accumulating Hb-loaded particles was the liver. The half-life of nano-sized PCL HbP was 3.1 times as long as the micro-sized PCL HbP. Also, Nano-sized as well as a PEGylated surface on HbP is beneficial for prolonged blood residence (7.2 fold increase).

External nutrient loading from land, sea and atmosphere to all 656 Swedish coastal water bodies.

PubMed

Bryhn, Andreas C; Dimberg, Peter H; Bergström, Lena; Fredriksson, Ronny E; Mattila, Johanna; Bergström, Ulf

2017-01-30

Identifying the main sources of nutrient loading is a key factor for efficient mitigation of eutrophication. This study has investigated the pathways of external nutrient loading to 656 coastal water bodies along the entire Swedish coastline. The studied water bodies have been delineated to meet requirements in the European Union's Water Framework Directive, and recent status assessments have shown that 57% of them fail to attain good or high ecological status with respect to nutrients. The analysis in the study was performed on data from mass-balance based nutrient budgets computed using the modelling framework Vattenwebb. The external nutrient contribution from the sea to the water bodies was highly variable, ranging from about 1% to nearly 100%, but the median contribution was >99% of the total external loading regarding both nitrogen and phosphorus. External loading from the atmosphere and local catchment area played a minor role in general. However, 45 coastal water bodies received >25% of the external nitrogen and phosphorus from their catchments. Loading from land typically peaked in April following ice-break and snow melting and was comparatively low during summer. The results indicate that for many eutrophicated Swedish coastal water bodies, nutrient abatement is likely to be optimally effective when potential measures in all of the catchment area of the concerned sea basin are considered. Local-scale mitigation in single water bodies will likely be locally effective only in the small proportion of areas where water and thereby also nutrient input from the catchment is high compared to the influx from the sea. Future studies should include nutrient reduction scenarios in order to refine these conclusions and to identify relevant spatial scales for coastal eutrophication mitigation measures from a water body perspective. Copyright © 2017 Elsevier Ltd. All rights reserved.

Shock waves on complex networks

NASA Astrophysics Data System (ADS)

Mones, Enys; Araújo, Nuno A. M.; Vicsek, Tamás; Herrmann, Hans J.

2014-05-01

Power grids, road maps, and river streams are examples of infrastructural networks which are highly vulnerable to external perturbations. An abrupt local change of load (voltage, traffic density, or water level) might propagate in a cascading way and affect a significant fraction of the network. Almost discontinuous perturbations can be modeled by shock waves which can eventually interfere constructively and endanger the normal functionality of the infrastructure. We study their dynamics by solving the Burgers equation under random perturbations on several real and artificial directed graphs. Even for graphs with a narrow distribution of node properties (e.g., degree or betweenness), a steady state is reached exhibiting a heterogeneous load distribution, having a difference of one order of magnitude between the highest and average loads. Unexpectedly we find for the European power grid and for finite Watts-Strogatz networks a broad pronounced bimodal distribution for the loads. To identify the most vulnerable nodes, we introduce the concept of node-basin size, a purely topological property which we show to be strongly correlated to the average load of a node.

14 CFR 25.301 - Loads.

Code of Federal Regulations, 2010 CFR

2010-01-01

... significantly change the distribution of external or internal loads, this redistribution must be taken into... loads multiplied by prescribed factors of safety). Unless otherwise provided, prescribed loads are limit...

Electrostimulated Release of Neutral Drugs from Polythiophene Nanoparticles: Smart Regulation of Drug-Polymer Interactions.

PubMed

Puiggalí-Jou, Anna; Micheletti, Paolo; Estrany, Francesc; Del Valle, Luis J; Alemán, Carlos

2017-09-01

Poly(3,4-ethylenedioxythiophene) (PEDOT) nanoparticles are loaded with curcumin and piperine by in situ emulsion polymerization using dodecyl benzene sulfonic acid both as a stabilizer and a doping agent. The loaded drugs affect the morphology, size, and colloidal stability of the nanoparticles. Furthermore, kinetics studies of nonstimulated drug release have evidenced that polymer···drug interactions are stronger for curcumin than for piperine. This observation suggests that drug delivery systems based on combination of the former drug with PEDOT are much appropriated to show an externally tailored release profile. This is demonstrated by comparing the release profiles obtained in presence and absence of electrical stimulus. Results indicate that controlled and time-programmed release of curcumin is achieved in a physiological medium by applying a negative voltage of -1.25 V to loaded PEDOT nanoparticles. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Hydrodynamic interactions induce movement against an external load in a ratchet dimer Brownian motor.

PubMed

Fornés, José A

2010-01-15

We use the Brownian dynamics with hydrodynamic interactions simulation in order to describe the movement of a elastically coupled dimer Brownian motor in a ratchet potential. The only external forces considered in our system were the load, the random thermal noise and an unbiased thermal fluctuation. For a given set of parameters we observe direct movement against the load force if hydrodynamic interactions were considered.

The effect of glenosphere diameter in reverse shoulder arthroplasty on muscle force, joint load, and range of motion.

PubMed

Langohr, G Daniel G; Giles, Joshua W; Athwal, George S; Johnson, James A

2015-06-01

Little is known about the effects of glenosphere diameter on shoulder joint loads. The purpose of this biomechanical study was to investigate the effects of glenosphere diameter on joint load, load angle, and total deltoid force required for active abduction and range of motion in internal/external rotation and abduction. A custom, instrumented reverse shoulder arthroplasty implant system capable of measuring joint load and varying glenosphere diameter (38 and 42 mm) and glenoid offset (neutral and lateral) was implanted in 6 cadaveric shoulders to provide at least 80% power for all variables. A shoulder motion simulator was used to produce active glenohumeral and scapulothoracic motion. All implant configurations were tested with active and passive motion with joint kinematics, loads, and moments recorded. At neutral and lateralized glenosphere positions, increasing diameter significantly increased joint load (+12 ± 21 N and +6 ± 9 N; P < .01) and deltoid load required for active abduction (+9 ± 22 N and +11 ± 15 N; P < .02), whereas joint load angle was unaffected (P > .8). Passive internal rotation was reduced with increased diameter at both neutral and lateralized glenosphere positions (-6° ± 6° and -12° ± 6°; P < .002); however, external rotation was not affected (P > .05). At neutral glenosphere position, increasing diameter increased the maximum angles of both adduction (+1° ± 1°; P = .03) and abduction (+8° ± 9°; P < .05). Lateralization also increased abduction range of motion compared with neutral (P < .01). Although increasing glenosphere diameter significantly increased joint load and deltoid force, the clinical impact of these changes is presently unclear. Internal rotation, however, was reduced, which contradicts previous bone modeling studies, which we postulate is due to increased posterior capsular tension as it is forced to wrap around a larger 42 mm implant assembly. Copyright © 2015 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Elsevier Inc. All rights reserved.

Genetic selection to increase bone strength affects prevalence of keel bone damage and egg parameters in commercially housed laying hens.

PubMed

Stratmann, A; Fröhlich, E K F; Gebhardt-Henrich, S G; Harlander-Matauschek, A; Würbel, H; Toscano, M J

2016-05-01

The prevalence of keel bone damage as well as external egg parameters of 2 pure lines divergently selected for high (H) and low (L) bone strength were investigated in 2 aviary systems under commercial conditions. A standard LSL hybrid was used as a reference group. Birds were kept mixed per genetic line (77 hens of the H and L line and 201 or 206 hens of the LSL line, respectively, per pen) in 8 pens of 2 aviary systems differing in design. Keel bone status and body mass of 20 focal hens per line and pen were assessed at 17, 18, 23, 30, 36, 43, 52, and 63 wk of age. External egg parameters (i.e., egg mass, eggshell breaking strength, thickness, and mass) were measured using 10 eggs per line at both 38 and 57 wk of age. Body parameters (i.e. tarsus and third primary wing feather length to calculate index of wing loading) were recorded at 38 wk of age and mortality per genetic line throughout the laying cycle. Bone mineral density (BMD) of 15 keel bones per genetic line was measured after slaughter to confirm assignment of the experimental lines. We found a greater BMD in the H compared with the L and LSL lines. Fewer keel bone fractures and deviations, a poorer external egg quality, as well as a lower index of wing loading were found in the H compared with the L line. Mortality was lower and production parameters (e.g., laying performance) were higher in the LSL line compared with the 2 experimental lines. Aviary design affected prevalence of keel bone damage, body mass, and mortality. We conclude that selection of specific bone traits associated with bone strength as well as the related differences in body morphology (i.e., lower index of wing loading) have potential to reduce keel bone damage in commercial settings. Also, the housing environment (i.e., aviary design) may have additive effects. © 2016 Poultry Science Association Inc.

Effects of external mechanical loading on phase diagrams and dielectric properties in epitaxial ferroelectric thin films with anisotropic in-plane misfit strains

NASA Astrophysics Data System (ADS)

Qiu, J. H.; Jiang, Q.

2007-02-01

A phenomenological Landau-Devonshine theory is used to describe the effects of external mechanical loading on equilibrium polarization states and dielectric properties in epitaxial ferroelectric thin films grown on dissimilar orthorhombic substrates which induce anisotropic misfit strains in the film plane. The calculation focuses on single-domain perovskite BaTiO3 and PbTiO3 thin films on the assumption that um1=-um2. Compared with the phase diagrams without external loading, the characteristic features of "misfit strain-misfit strain" phase diagrams at room temperature are the presence of paraelectric phase and the strain-induced ferroelectric to paraelectric phase transition. Due to the external loading, the "misfit strain-stress" and "stress-temperature" phase diagrams also have drastic changes, especially for the vanishing of paraelectric phase in "misfit strain-stress" phase map and the appearance of possible ferroelectric phases. We also investigate the dielectric properties and the tunability of both BaTiO3 and PbTiO3 thin films. We find that the external stress dependence of phase diagrams and dielectric properties largely depends on strain anisotropy as well.

Effects of load carriage and footwear on lower extremity kinetics and kinematics during overground walking.

PubMed

Dames, Kevin D; Smith, Jeremy D

2016-10-01

Kinetic and kinematic responses during walking vary by footwear condition. Load carriage also influences gait patterns, but it is unclear how an external load influences barefoot walking. Twelve healthy adults (5 women, 7 men) with no known gait abnormalities participated in this study (age=23±3years, height=1.73±0.11m, and mass=70.90±12.67kg). Ground reaction forces and 3D motion were simultaneously collected during overground walking at 1.5ms -1 in four conditions: Barefoot Unloaded, Shod Unloaded, Barefoot Loaded, and Shod Loaded. Barefoot walking reduced knee and hip joint ranges of motion, as well as stride length, stance time, swing time, and double support time. Load carriage increased stance and double support times. The 15% body weight load increased GRFs ∼15%. Walking barefoot reduced peak anteroposterior GRFs but not peak vertical GRFs. Load carriage increased hip, knee, and ankle joint moments and powers, while walking barefoot increased knee and hip moments and powers. Thus, spatiotemporal and kinematic adjustments to walking barefoot decrease GRFs but increase knee and hip kinetic measures during overground walking. The ankle seems to be less affected by these footwear conditions. Regardless of footwear, loading requires larger GRFs, joint loads, and joint powers. Copyright © 2016 Elsevier B.V. All rights reserved.

Resistance of three implant-abutment interfaces to fatigue testing

PubMed Central

RIBEIRO, Cleide Gisele; MAIA, Maria Luiza Cabral; SCHERRER, Susanne S.; CARDOSO, Antonio Carlos; WISKOTT, H. W. Anselm

2011-01-01

The design and retentive properties of implant-abutment connectors affect the mechanical resistance of implants. A number of studies have been carried out to compare the efficacy of connecting mechanisms between abutment and fixture. Objectives The aims of this study were: 1) to compare 3 implant-abutment interfaces (external hexagon, internal hexagon and cone-in-cone) regarding the fatigue resistance of the prosthetic screw, 2) to evaluate the corresponding mode of failure, and 3) to compare the results of this study with data obtained in previous studies on Nobel Biocare and Straumann connectors. Materials and Methods In order to duplicate the alternating and multivectorial intraoral loading pattern, the specimens were submitted to the rotating cantilever beam test. The implants, abutments and restoration analogs were spun around their longitudinal axes while a perpendicular force was applied to the external end. The objective was to determine the force level at which 50% of the specimens survived 106 load cycles. The mean force levels at which 50% failed and the corresponding 95% confidence intervals were determined using the staircase procedure. Results The external hexagon interface presented better than the cone-in-cone and internal hexagon interfaces. There was no significant difference between the cone-in-cone and internal hex interfaces. Conclusion Although internal connections present a more favorable design, this study did not show any advantage in terms of strength. The external hexagon connector used in this study yielded similar results to those obtained in a previous study with Nobel Biocare and Straumann systems. However, the internal connections (cone-in-cone and internal hexagon) were mechanically inferior compared to previous results. PMID:21710094

Load apparatus and method for bolt-loaded compact tension test specimen

DOEpatents

Buescher, B.J. Jr.; Lloyd, W.R.; Ward, M.B.; Epstein, J.S.

1997-02-04

A bolt-loaded compact tension test specimen load apparatus includes: (a) a body having first and second opposing longitudinal ends, the first end comprising an externally threaded portion sized to be threadedly received within the test specimen threaded opening; (b) a longitudinal loading rod having first and second opposing longitudinal ends, the loading rod being slidably received in a longitudinal direction within the body internally through the externally threaded portion and slidably extending longitudinally outward of the body first longitudinal end; (c) a force sensitive transducer slidably received within the body and positioned to engage relative to the loading rod second longitudinal end; and (d) a loading bolt threadedly received relative to the body, the loading bolt having a bearing end surface and being positioned to bear against the transducer to forcibly sandwich the transducer between the loading bolt and loading rod. Also disclosed is a method of in situ determining applied force during crack propagation in a bolt-loaded compact tension test specimen. 6 figs.

Load apparatus and method for bolt-loaded compact tension test specimen

DOEpatents

Buescher, Jr., Brent J.; Lloyd, W. Randolph; Ward, Michael B.; Epstein, Jonathan S.

1997-01-01

A bolt-loaded compact tension test specimen load apparatus includes: a) a body having first and second opposing longitudinal ends, the first end comprising an externally threaded portion sized to be threadedly received within the test specimen threaded opening; b) a longitudinal loading rod having first and second opposing longitudinal ends, the loading rod being slidably received in a longitudinal direction within the body internally through the externally threaded portion and slidably extending longitudinally outward of the body first longitudinal end; c) a force sensitive transducer slidably received within the body and positioned to engage relative to the loading rod second longitudinal end; and d) a loading bolt threadedly received relative to the body, the loading bolt having a bearing end surface and being positioned to bear against the transducer to forcibly sandwich the transducer between the loading bolt and loading rod. Also disclosed is a method of in situ determining applied force during crack propagation in a bolt-loaded compact tension test specimen.

Water Quality, Hydrology, and Simulated Response to Changes in Phosphorus Loading of Butternut Lake, Price and Ashland Counties, Wisconsin, with Special Emphasis on the Effects of Internal Phosphorus Loading in a Polymictic Lake

USGS Publications Warehouse

Robertson, Dale M.; Rose, William J.

2008-01-01

Butternut Lake is a 393-hectare, eutrophic to hypereutrophic lake in northcentral Wisconsin. After only minor improvements in water quality were observed following several actions taken to reduce the nutrient inputs to the lake, a detailed study was conducted from 2002 to 2007 by the U.S. Geological Survey to better understand how the lake functions. The goals of this study were to describe the water quality and hydrology of the lake, quantify external and internal sources of phosphorus, and determine the effects of past and future changes in phosphorus inputs on the water quality of the lake. Since the early 1970s, the water quality of Butternut Lake has changed little in response to nutrient reductions from the watershed. The largest changes were in near-surface total phosphorus concentrations: August concentrations decreased from about 0.09 milligrams per liter (mg/L) to about 0.05 mg/L, but average summer concentrations decreased only from about 0.055-0.060 mg/L to about 0.045 mg/L. Since the early 1970s, only small changes were observed in chlorophyll a concentrations and water clarity (Secchi depths). All major water and phosphorus sources, including the internal release of phosphorus from the sediments (internal loading), were measured directly, and minor sources were estimated to construct detailed water and phosphorus budgets for the lake during monitoring years (MY) 2003 and 2004. During these years, Butternut Creek, Spiller Creek, direct precipitation, small tributaries and near-lake drainage area, and ground water contributed about 62, 20, 8, 7, and 3 percent of the inflow, respectively. The average annual load of phosphorus to the lake was 2,540 kilograms (kg), of which 1,590 kg came from external sources (63 percent) and 945 kg came from the sediments in the lake (37 percent). Of the total external sources, Butternut Creek, Spiller Creek, small tributaries and near-lake drainage area, septic systems, precipitation, and ground water contributed about 63, 23, 9, 3, 1, and 1 percent, respectively. Because of the high internal phosphorus loading, the eutrophication models used in this study were unable to simulate the observed water-quality characteristics in the lake without incorporating this source of phosphorus. However, when internal loading of phosphorus was added to the BATHTUB model, it accurately simulated the average water-quality characteristics measured in MY 2003 and 2004. Model simulations demonstrated a relatively linear response between in-lake total phosphorus concentrations and external phosphorus loading; however, the changes in concentrations were smaller than the changes in external phosphorus loadings (about 25-40 percent of the change in phosphorus loading). Changes in chlorophyll a concentrations, the percentage of days with algal blooms, and Secchi depths were nonlinear and had a greater response to reductions in phosphorus loading than to increases in phosphorus loading. A 50-percent reduction in external phosphorus loading caused an 18-percent decrease in chlorophyll a concentrations, a 41-percent decrease in the percentage of days with algal blooms, and a 12-percent increase in Secchi depth. When the additional internal phosphorus loading was removed from model simulations, all of these constituents showed a much greater response to changes in external phosphorus loading. Because of Butternut Lake's morphometry, it is polymictic, which means it mixes frequently and does not develop stable thermal stratification throughout the summer. This characteristic makes it more vulnerable than dimictic lakes, which mix in spring and fall and develop stable thermal stratification during summer, to the high internal phosphorus loading that has resulted from historically high, nonnatural, external phosphorus loading. In polymictic lakes, the phosphorus released from the sediments is mixed into the upper part of the lake throughout summer. Once Butternut Lake became hypereutrophic (very p

7 CFR 1710.206 - Approval requirements for load forecasts prepared pursuant to approved load forecast work plans.

Code of Federal Regulations, 2010 CFR

2010-01-01

... narrative shall address the overall approach, time periods, and expected internal and external uses of the forecast. Examples of internal uses include providing information for developing or monitoring demand side... suppliers. Examples of external uses include meeting state and Federal regulatory requirements, obtaining...

Gas-liquid two-phase flow behaviors and performance characteristics of proton exchange membrane fuel cells in a short-term microgravity environment

NASA Astrophysics Data System (ADS)

Guo, Hang; Liu, Xuan; Zhao, Jian Fu; Ye, Fang; Ma, Chong Fang

2017-06-01

In this work, proton exchange membrane fuel cells (PEMFCs) with transparent windows are designed to study the gas-liquid two-phase flow behaviors inside flow channels and the performance of a PEMFC with vertical channels and a PEMFC with horizontal channels in a normal gravity environment and a 3.6 s short-term microgravity environment. Experiments are conducted under high external circuit load and low external circuit load at low temperature where is 35 °C. The results of the present experimental work demonstrate that the performance and the gas-liquid two-phase flow behaviors of the PEMFC with vertical channels exhibits obvious changes when the PEMFCs enter the 3.6 s short-term microgravity environment from the normal gravity environment. Meanwhile, the performance of the PEMFC with vertical channels increases after the PEMFC enters the 3.6 s short-term microgravity environment under high external circuit load, while under low external circuit load, the PEMFC with horizontal channels exhibits better performance in both the normal gravity environment and the 3.6 s short-term microgravity environment.

Harnessing the wandering mind: the role of perceptual load.

PubMed

Forster, Sophie; Lavie, Nilli

2009-06-01

Perceptual load is a key determinant of distraction by task-irrelevant stimuli (e.g., Lavie, N. (2005). Distracted and confused?: Selective attention under load. Trends in Cognitive Sciences, 9, 75-82). Here we establish the role of perceptual load in determining an internal form of distraction by task-unrelated thoughts (TUTs or "mind-wandering"). Four experiments demonstrated reduced frequency of TUTs with high compared to low perceptual load in a visual-search task. Alternative accounts in terms of increased demands on responses, verbal working memory or motivation were ruled out and clear effects of load were found for unintentional TUTs. Individual differences in load effects on internal (TUTs) and external (response-competition) distractors were correlated. These results suggest that exhausting attentional capacity in task-relevant processing under high perceptual load can reduce processing of task-irrelevant information from external and internal sources alike.

Effects of transverse shear deformation on buckling of laminated cylinders as a function of thickness and ply orientation

NASA Technical Reports Server (NTRS)

Jegley, Dawn C.

1987-01-01

Buckling loads of thick-walled, orthotropic, simply-supported right circular cylinders are predicted using a new higher-order transverse shear deformation theory. The higher-order theory shows that, by more accurately accounting for transverse shear deformation effects, the predicted buckling load may be reduced by as much as 80 percent compared to predictions based on conventional transverse shear deformation theory. A parametric study of the effect of ply orientation on the buckling load of axially compressed cylinders indicates that laminates containing 0 deg plies are the most sensitive to transverse shear deformation effects. Interaction curves for buckling of cylinders with axial compressive and external pressure loadings indicate that buckling loads due to external pressure loadings are much less sensitive to transverse shear deformation effects than those due to axial compressive loadings.

Mechanical evaluation of external skeletal fixator-intramedullary pin tie-in configurations applied to cadaveral humeri from red-tailed hawks (Buteo jamaicensis).

PubMed

Van Wettere, Arnaud J; Redig, Patrick T; Wallace, Larry J; Bourgeault, Craig A; Bechtold, Joan E

2009-12-01

Use of external skeletal fixator-intramedullary pin (ESF-IM) tie-in fixators is an adjustable and effective method of fracture fixation in birds. The objective of this study was to determine the contribution of each of the following parameters to the compressive and torsional rigidity of an ESF-IM pin tie-in applied to avian bones with an osteotomy gap: (1) varying the fixation pin position in the proximal bone segment and (2) increasing the number of fixation pins in one or both bone segments. ESF-IM pin tie-in constructs were applied to humeri harvested from red-tailed hawks (Buteo jamaicensis) (n=24) that had been euthanatized for clinical reasons. Constructs with a variation in the placement of the proximal fixation pin and with 2, 3, or 4 fixation pins applied to avian bone with an osteotomy gap were loaded to a defined displacement in torque and axial compression. Response variables were determined from resulting load-displacement curves (construct stiffness, load at 1-mm displacement). Increasing the number of fixation pins from 1 to 2 per bone segment significantly increased the stiffness in torque (110%) and compression (60%), and the safe load in torque (107%) and compression (50%). Adding a fixation pin to the distal bone segment to form a 3-pin fixator significantly increased the stiffness (27%) and safe load (20%) in torque but not in axial compression. In the configuration with 2 fixation pins, placing the proximal pin distally in the proximal bone segment significantly increased the stiffness in torque (28%), and the safe load in torque (23%) and in axial compression (32%). Results quantified the relative importance of specific parameters affecting the rigidity of ESF-IM pin tie-in constructs as applied to unstable bone fracture models in birds.

Effect of abutment screw length and cyclic loading on removal torque in external and internal hex implants.

PubMed

Mohammed, Hnd Hadi; Lee, Jin-Han; Bae, Ji-Myung; Cho, Hye-Won

2016-02-01

The purpose of this study was to evaluate the effects of abutment screw length and cyclic loading on the removal torque (RTV) in external hex (EH) and internal hex (IH) implants. Forty screw-retained single crowns were connected to external and internal hex implants. The prepared titanium abutment screws were classified into 8 groups based on the number of threads (n = 5 per group): EH 12.5, 6.5, 3.5, 2.5 and IH 6.5, 5, 3.5, 2.5 threads. The abutment screws were tightened with 20 Ncm torque twice with 10-minute intervals. After 5 minutes, the initial RTVs of the abutment screws were measured with a digital torque gauge (MGT12). A customized jig was constructed to apply a load along the implant long axis at the central fossa of the maxillary first molar. The post-loading RTVs were measured after 16,000 cycles of mechanical loading with 50 N at a 1-Hz frequency. Statistical analysis included one-way analysis of variance and paired t-tests. The post-loading RTVs were significantly lower than the initial RTVs in the EH 2.5 thread and IH 2.5 thread groups (P<.05). The initial RTVs exhibited no significant differences among the 8 groups, whereas the post-loading RTVs of the EH 6.5 and EH 3.5 thread groups were higher than those of the IH 3.5 thread group (P<.05). Within the limitations of this study, the external hex implants with short screw lengths were more advantageous than internal hex implants with short screw lengths in torque maintenance after cyclic loading.

Effect of abutment screw length and cyclic loading on removal torque in external and internal hex implants

PubMed Central

Mohammed, Hnd Hadi; Lee, Jin-Han; Bae, Ji-Myung

2016-01-01

PURPOSE The purpose of this study was to evaluate the effects of abutment screw length and cyclic loading on the removal torque (RTV) in external hex (EH) and internal hex (IH) implants. MATERIALS AND METHODS Forty screw-retained single crowns were connected to external and internal hex implants. The prepared titanium abutment screws were classified into 8 groups based on the number of threads (n = 5 per group): EH 12.5, 6.5, 3.5, 2.5 and IH 6.5, 5, 3.5, 2.5 threads. The abutment screws were tightened with 20 Ncm torque twice with 10-minute intervals. After 5 minutes, the initial RTVs of the abutment screws were measured with a digital torque gauge (MGT12). A customized jig was constructed to apply a load along the implant long axis at the central fossa of the maxillary first molar. The post-loading RTVs were measured after 16,000 cycles of mechanical loading with 50 N at a 1-Hz frequency. Statistical analysis included one-way analysis of variance and paired t-tests. RESULTS The post-loading RTVs were significantly lower than the initial RTVs in the EH 2.5 thread and IH 2.5 thread groups (P<.05). The initial RTVs exhibited no significant differences among the 8 groups, whereas the post-loading RTVs of the EH 6.5 and EH 3.5 thread groups were higher than those of the IH 3.5 thread group (P<.05). CONCLUSION Within the limitations of this study, the external hex implants with short screw lengths were more advantageous than internal hex implants with short screw lengths in torque maintenance after cyclic loading. PMID:26949489

Dynamic characteristics of motor-gear system under load saltations and voltage transients

NASA Astrophysics Data System (ADS)

Bai, Wenyu; Qin, Datong; Wang, Yawen; Lim, Teik C.

2018-02-01

In this paper, a dynamic model of a motor-gear system is proposed. The model combines a nonlinear permeance network model (PNM) of a squirrel-cage induction motor and a coupled lateral-torsional dynamic model of a planetary geared rotor system. The external excitations including voltage transients and load saltations, as well as the internal excitations such as spatial effects, magnetic circuits topology and material nonlinearity in the motor, and time-varying mesh stiffness and damping in the planetary gear system are considered in the proposed model. Then, the simulation results are compared with those predicted by the electromechanical model containing a dynamic motor model with constant inductances. The comparison showed that the electromechanical system model with the PNM motor model yields more reasonable results than the electromechanical system model with the lumped-parameter electric machine. It is observed that electromechanical coupling effect can induce additional and severe gear vibrations. In addition, the external conditions, especially the voltage transients, will dramatically affect the dynamic characteristics of the electromechanical system. Finally, some suggestions are offered based on this analysis for improving the performance and reliability of the electromechanical system.

Phase Synchronization and Desynchronization of Structural Response Induced by Turbulent and External Sound

NASA Technical Reports Server (NTRS)

Maestrello, Lucio

2002-01-01

Acoustic and turbulent boundary layer flow loadings over a flexible structure are used to study the spatial-temporal dynamics of the response of the structure. The stability of the spatial synchronization and desynchronization by an active external force is investigated with an array of coupled transducers on the structure. In the synchronous state, the structural phase is locked, which leads to the formation of spatial patterns while the amplitude peaks exhibit chaotic behaviors. Large amplitude, spatially symmetric loading is superimposed on broadband, but in the desynchronized state, the spectrum broadens and the phase space is lost. The resulting pattern bears a striking resemblance to phase turbulence. The transition is achieved by using a low power external actuator to trigger broadband behaviors from the knowledge of the external acoustic load inducing synchronization. The changes are made favorably and efficiently to alter the frequency distribution of power, not the total power level. Before synchronization effects are seen, the panel response to the turbulent boundary layer loading is discontinuously spatio-temporally correlated. The stability develops from different competing wavelengths; the spatial scale is significantly shorter than when forced with the superimposed external sound. When the external sound level decreases and the synchronized phases are lost, changes in the character of the spectra can be linked to the occurrence of spatial phase transition. These changes can develop broadband response. Synchronized responses of fuselage structure panels have been observed in subsonic and supersonic aircraft; results from two flights tests are discussed.

Loading direction regulates the affinity of ADP for kinesin.

PubMed

Uemura, Sotaro; Ishiwata, Shin'ichi

2003-04-01

Kinesin is an ATP-driven molecular motor that moves processively along a microtubule. Processivity has been explained as a mechanism that involves alternating single- and double-headed binding of kinesin to microtubules coupled to the ATPase cycle of the motor. The internal load imposed between the two bound heads has been proposed to be a key factor regulating the ATPase cycle in each head. Here we show that external load imposed along the direction of motility on a single kinesin molecule enhances the binding affinity of ADP for kinesin, whereas an external load imposed against the direction of motility decreases it. This coupling between loading direction and enzymatic activity is in accord with the idea that the internal load plays a key role in the unidirectional and cooperative movement of processive motors.

Relationships Between the External and Internal Training Load in Professional Soccer: What Can We Learn From Machine Learning?

PubMed

Jaspers, Arne; De Beéck, Tim Op; Brink, Michel S; Frencken, Wouter G P; Staes, Filip; Davis, Jesse J; Helsen, Werner F

2018-05-01

Machine learning may contribute to understanding the relationship between the external load and internal load in professional soccer. Therefore, the relationship between external load indicators (ELIs) and the rating of perceived exertion (RPE) was examined using machine learning techniques on a group and individual level. Training data were collected from 38 professional soccer players over 2 seasons. The external load was measured using global positioning system technology and accelerometry. The internal load was obtained using the RPE. Predictive models were constructed using 2 machine learning techniques, artificial neural networks and least absolute shrinkage and selection operator (LASSO) models, and 1 naive baseline method. The predictions were based on a large set of ELIs. Using each technique, 1 group model involving all players and 1 individual model for each player were constructed. These models' performance on predicting the reported RPE values for future training sessions was compared with the naive baseline's performance. Both the artificial neural network and LASSO models outperformed the baseline. In addition, the LASSO model made more accurate predictions for the RPE than did the artificial neural network model. Furthermore, decelerations were identified as important ELIs. Regardless of the applied machine learning technique, the group models resulted in equivalent or better predictions for the reported RPE values than the individual models. Machine learning techniques may have added value in predicting RPE for future sessions to optimize training design and evaluation. These techniques may also be used in conjunction with expert knowledge to select key ELIs for load monitoring.

Influence of parafunctional loading and prosthetic connection on stress distribution: a 3D finite element analysis.

PubMed

Torcato, Leonardo Bueno; Pellizzer, Eduardo Piza; Verri, Fellippo Ramos; Falcón-Antenucci, Rosse Mary; Santiago Júnior, Joel Ferreira; de Faria Almeida, Daniel Augusto

2015-11-01

Clinicians should consider parafunctional occlusal load when planning treatment. Prosthetic connections can reduce the stress distribution on an implant-supported prosthesis. The purpose of this 3-dimensional finite element study was to assess the influence of parafunctional loading and prosthetic connections on stress distribution. Computer-aided design software was used to construct 3 models. Each model was composed of a bone and an implant (external hexagon, internal hexagon, or Morse taper) with a crown. Finite element analysis software was used to generate the finite element mesh and establish the loading and boundary conditions. A normal force (200-N axial load and 100-N oblique load) and parafunctional force (1000-N axial and 500-N oblique load) were applied. Results were visualized as the maximum principal stress. Three-way analysis of variance and Tukey test were performed, and the percentage of contribution of each variable to the stress concentration was calculated from sum-of squares-analysis. Stress was concentrated around the implant at the cortical bone, and models with the external hexagonal implant showed the highest stresses (P<.001). Oblique loads produced high tensile stress concentrations on the site opposite the load direction. Internal connection implants presented the most favorable biomechanical situation, whereas the least favorable situation was the biomechanical behavior of external connection implants. Parafunctional loading increased the magnitude of stress by 3 to 4 times. Copyright © 2015 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.

Evaluation of muscle activity for loaded and unloaded dynamic squats during vertical whole-body vibration.

PubMed

Hazell, Tom J; Kenno, Kenji A; Jakobi, Jennifer M

2010-07-01

The purpose of this investigation was to examine if the addition of a light external load would enhance whole-body vibration (WBV)-induced increases in muscle activity during dynamic squatting in 4 leg muscles. Thirteen recreationally active male university students performed a series of dynamic squats (unloaded with no WBV, unloaded with WBV, loaded with no WBV, and loaded with WBV). The load was set to 30% of body mass and WBV included 25-, 35-, and 45-Hz frequencies with 4-mm amplitude. Muscle activity was recorded with surface electromyography (EMG) on the vastus lateralis (VL), biceps femoris (BF), tibialis anterior (TA), and gastrocnemius (GC) and is reported as EMGrms (root mean square) normalized to %maximal voluntary exertion. During unloaded dynamic squats, exposure to WBV (45 Hz) significantly (p < 0.05) increased baseline muscle activity in all muscles, except the TA compared with no WBV. Adding a light external load without WBV increased baseline muscle activity of the squat exercise in all muscles but decreased the TA. This loaded level of muscle activity was further increased with WBV (45 Hz) in all muscles. The WBV-induced increases in muscle activity in the loaded condition (approximately 3.5%) were of a similar magnitude to the WBV-induced increases during the unloaded condition (approximately 2.5%) demonstrating the addition of WBV to unloaded or loaded dynamic squatting results in an increase in muscle activity. These results demonstrate the potential effectiveness of using external loads with exposure to WBV.

Swim stress, motion, and deformation of active matter: effect of an external field.

PubMed

Takatori, Sho C; Brady, John F

2014-12-21

We analyze the stress, dispersion, and average swimming speed of self-propelled particles subjected to an external field that affects their orientation and speed. The swimming trajectory is governed by a competition between the orienting influence (i.e., taxis) associated with the external (e.g., magnetic, gravitational, thermal, nutrient concentration) field versus the effects that randomize the particle orientations (e.g., rotary Brownian motion and/or an intrinsic tumbling mechanism like the flagella of bacteria). The swimmers' motion is characterized by a mean drift velocity and an effective translational diffusivity that becomes anisotropic in the presence of the orienting field. Since the diffusivity yields information about the micromechanical stress, the anisotropy generated by the external field creates a normal stress difference in the recently developed "swim stress" tensor [Takatori, Yan, and Brady, Phys. Rev. Lett., 2014]. This property can be exploited in the design of soft, compressible materials in which their size, shape, and motion can be manipulated and tuned by loading the material with active swimmers. Since the swimmers exert different normal stresses in different directions, the material can compress/expand, elongate, and translate depending on the external field strength. Such an active system can be used as nano/micromechanical devices and motors. Analytical solutions are corroborated by Brownian dynamics simulations.

Load identification approach based on basis pursuit denoising algorithm

NASA Astrophysics Data System (ADS)

Ginsberg, D.; Ruby, M.; Fritzen, C. P.

2015-07-01

The information of the external loads is of great interest in many fields of structural analysis, such as structural health monitoring (SHM) systems or assessment of damage after extreme events. However, in most cases it is not possible to measure the external forces directly, so they need to be reconstructed. Load reconstruction refers to the problem of estimating an input to a dynamic system when the system output and the impulse response functions are usually the knowns. Generally, this leads to a so called ill-posed inverse problem, which involves solving an underdetermined linear system of equations. For most practical applications it can be assumed that the applied loads are not arbitrarily distributed in time and space, at least some specific characteristics about the external excitation are known a priori. In this contribution this knowledge was used to develop a more suitable force reconstruction method, which allows identifying the time history and the force location simultaneously by employing significantly fewer sensors compared to other reconstruction approaches. The properties of the external force are used to transform the ill-posed problem into a sparse recovery task. The sparse solution is acquired by solving a minimization problem known as basis pursuit denoising (BPDN). The possibility of reconstructing loads based on noisy structural measurement signals will be demonstrated by considering two frequently occurring loading conditions: harmonic excitation and impact events, separately and combined. First a simulation study of a simple plate structure is carried out and thereafter an experimental investigation of a real beam is performed.

Interaction of external alkali metal ions with the Na-K pump of human erythrocytes: a comparison of their effects on activation of the pump and on the rate of ouabain binding

PubMed Central

1978-01-01

The effects of external alkali metal ions on the rate of ouabain binding and on the rate of the Na-K pump were examined in human red blood cells. In Na-containing solutions, K, Cs, and Li decreased the rate of ouabain binding. For K and Cs, the kinetics of this effect were similar to those for their activation of the pump. In Na-free (choline- substituted) solutions the rate of ouabain binding was decreased by K whereas it was promoted by Cs and Li. External Na increased the rate of ouabain binding whether or not external K was present, and the kinetics of this effect were not the same as those for inhibition of the pump by Na. These findings are interpreted to mean that not only do the cations affect ouabain binding at the external loading sites on the pump from which ions are translocated inward, but that there are additional sites on the external aspect of the pump at which cations can promote ouabain binding, and that these sites can be occupied by Li, Na, and Cs. It is postulated that these latter sites are those from which Na is discharged after outward translocation by the pump. PMID:702113

Coupled loads analysis for Space Shuttle payloads

NASA Technical Reports Server (NTRS)

Eldridge, J.

1992-01-01

Described here is a method for determining the transient response of, and the resultant loads in, a system exposed to predicted external forces. In this case, the system consists of four racks mounted on the inside of a space station resource node module (SSRNMO) which is mounted in the payload bay of the space shuttle. The predicted external forces are forcing functions which envelope worst case forces applied to the shuttle during liftoff and landing. This analysis, called a coupled loads analysis, is used to couple the payload and shuttle models together, determine the transient response of the system, and then recover payload loads, payload accelerations, and payload to shuttle interface forces.

Experimental and numerical investigation on laser-assisted bending of pre-loaded metal plate

NASA Astrophysics Data System (ADS)

Nowak, Zdzisław; Nowak, Marcin; Widłaszewski, Jacek; Kurp, Piotr

2018-01-01

The laser forming technique has an important disadvantage, which is the limitation of plastic deformation generated by a single laser beam pass. To increase the plastic deformation it is possible to apply external forces in the laser forming process. In this paper, we investigate the influence of external pre-loads on the laser bending of steel plate. The pre-loads investigated generate bending towards the laser beam. The thermal, elastic-plastic analysis is performed using the commercial nonlinear finite element analysis package ABAQUS. The focus of the paper is to identify how this pattern of the pre-load influence the final bend angle of the plate.

A predictive model of human performance.

NASA Technical Reports Server (NTRS)

Walters, R. F.; Carlson, L. D.

1971-01-01

An attempt is made to develop a model describing the overall responses of humans to exercise and environmental stresses for prediction of exhaustion vs an individual's physical characteristics. The principal components of the model are a steady state description of circulation and a dynamic description of thermal regulation. The circulatory portion of the system accepts changes in work load and oxygen pressure, while the thermal portion is influenced by external factors of ambient temperature, humidity and air movement, affecting skin blood flow. The operation of the model is discussed and its structural details are given.

Resistance training is accompanied by increases in hip strength and changes in lower extremity biomechanics during running.

PubMed

Snyder, Kelli R; Earl, Jennifer E; O'Connor, Kristian M; Ebersole, Kyle T

2009-01-01

Movement and muscle activity of the hip have been shown to affect movement of the lower extremity, and been related to injury. The purpose of this study was to determine if increased hip strength affects lower extremity mechanics during running. Within subject, repeated measures design. Fifteen healthy women volunteered. Hip abduction and external rotation strength were measured using a hand-held dynamometer. Three-dimensional biomechanical data of the lower extremity were collected during running using a high-speed motion capture system. Measurements were made before, at the mid-point, and after a 6-week strengthening program using closed-chain hip rotation exercises. Joint range of motion (rearfoot eversion, knee abduction, hip adduction, and internal rotation), eversion velocity, eversion angle at heel strike, and peak joint moments (rearfoot inversion, knee abduction, hip abduction, and external rotation) were analyzed using repeated measures analysis of variance (P

The effects of squatting footwear on three-dimensional lower limb and spine kinetics.

PubMed

Southwell, Daniel J; Petersen, Shane A; Beach, Tyson A C; Graham, Ryan B

2016-12-01

Altering footwear worn during performance of the barbell back squat has been shown to change motion patterns, but it is not completely understood how this affects biomechanical loading demands. The primary objective was to compare lower back and extremity net joint moments in 24 experienced weightlifters (12M, 12F) who performed 80% one-repetition maximum back squats under three different footwear conditions (barefoot, running shoes, weightlifting shoes). Results showed that there was a significant main effect of footwear condition on the knee extension moment (p=0.001), where the running and weightlifting shoes produced significantly larger moments than the barefoot condition. There was also a main effect of footwear condition on knee external rotation moments (p=0.002), where the weightlifting shoe produced significantly larger moments than both other conditions. At the hip, there was also a main effect of footwear condition on the extension moment (p=0.004), where the barefoot condition produced significantly larger moments than either the running shoe or weightlifting shoe condition. Lastly, there was also a significant main effect of footwear condition on both hip external (p=0.005) and internal (p=0.003) rotation moments, where the barefoot condition produced greater internal rotation and less external rotation moments than either shod condition. This study indicates that altering footwear conditions while performing the barbell back squat may redistribute the internal biomechanical loading patterns amongst the lower extremity joints and perhaps alter the musculoskeletal adaptations elicited. Copyright © 2016 Elsevier Ltd. All rights reserved.

Study on energy saving of subway station based on orthogonal experimental method

NASA Astrophysics Data System (ADS)

Guo, Lei

2017-05-01

With the characteristics of quick, efficient and large amount transport, the subway has become an important way to solve urban traffic congestion. As the subway environment will follow the change of external environment factors such as temperature and load of personnel changes, three-dimensional numerical simulations study is conducted by using CFD software for air distribution of subway platform. The influence of different loads (the supply air temperature and velocity of air condition, personnel load, heat flux of the wall) on the subway platform flow field are also analysed. The orthogonal experiment method is applied to the numerical simulation analysis for human comfort under different parameters. Based on those results, the functional relationship between human comfort and the boundary conditions of the platform is produced by multiple linear regression fitting method, the order of major boundary conditions which affect human comfort is obtained. The above study provides a theoretical basis for the final energy-saving strategies.

Relationships of cognitive load on eating and weight-related behaviors of young adults.

PubMed

Byrd-Bredbenner, Carol; Quick, Virginia; Koenings, Mallory; Martin-Biggers, Jennifer; Kattelmann, Kendra K

2016-04-01

Little is known about the relationship between weight-related behaviors and cognitive load (working memory available to complete mental activities like those required for planning meals, selecting foods, and other health-related decisions). Thus, the purpose of this study was to explore associations between cognitive load and eating behaviors, physical activity, body mass index (BMI), and waist circumference of college students. College students (n=1018) from 13 institutions completed an online survey assessing eating behaviors (e.g., routine and compensatory restraint, emotional eating, and fruit/vegetable intake), stress level, and physical activity level. BMI and waist circumference were measured by trained researchers. A cognitive load score was derived from stress level, time pressure/income needs, race and nationality. High cognitive load participants (n=425) were significantly (P<0.05) more likely to be female, older, and further along in school than those with low cognitive loads (n=593). Compared to low cognitive load participants, high cognitive load participants were significantly more likely to eat <5 cups of fruits/vegetables/day, have greater routine and compensatory restraint, and greater susceptibility to eating in response to external cues and emotional eating. Both males and females with high cognitive load scores had a non-significant trend toward higher BMIs, waist circumferences, and drinking more alcohol than low cognitive load counterparts. In conclusion, cognitive load may be an important contributor to health behaviors. Understanding how cognitive load may affect eating and other weight-related behaviors could potentially lead to improvements in the effectiveness of obesity prevention and intervention programs. Copyright © 2015 Elsevier Ltd. All rights reserved.

On mechanical mechanism of damage evolution in articular cartilage.

PubMed

Men, Yu-Tao; Jiang, Yan-Long; Chen, Ling; Zhang, Chun-Qiu; Ye, Jin-Duo

2017-09-01

Superficial lesions of cartilage are the direct indication of osteoarthritis. To investigate the mechanical mechanism of cartilage with micro-defect under external loading, a new plain strain numerical model with micro-defect was proposed and damage evolution progression in cartilage over time has been simulated, the parameter were studied including load style, velocity of load and degree of damage. The new model consists of the hierarchical structure of cartilage and depth-dependent arched fibers. The numerical results have shown that not only damage of the cartilage altered the distribution of the stress but also matrix and fiber had distinct roles in affecting cartilage damage, and damage in either matrix or fiber could promote each other. It has been found that the superficial cracks in cartilage spread preferentially along the tangent direction of the fibers. It is the arched distribution form of fibers that affects the crack spread of cartilage, which has been verified by experiment. During the process of damage evolution, its extension direction and velocity varied constantly with the damage degree. The rolling load could cause larger stress and strain than sliding load. Strain values of the matrix initially increased and then decreased gradually with the increase of velocity, and velocity had a greater effect on matrix than fibers. Damage increased steadily before reaching 50%, sharply within 50 to 85%, and smoothly and slowly after 85%. The finding of the paper may help to understand the mechanical mechanism why the cracks in cartilage spread preferentially along the tangent direction of the fibers. Copyright © 2017 Elsevier B.V. All rights reserved.

Bifunctional viscous nanovesicles co-loaded with resveratrol and gallic acid for skin protection against microbial and oxidative injuries.

PubMed

Vitonyte, Justina; Manca, Maria Letizia; Caddeo, Carla; Valenti, Donatella; Peris, Josè Esteban; Usach, Iris; Nacher, Amparo; Matos, Maria; Gutiérrez, Gemma; Orrù, Germano; Fernàndez-Busquets, Xavier; Fadda, Anna Maria; Manconi, Maria

2017-05-01

Resveratrol and gallic acid were co-loaded in phospholipid vesicles aiming at protecting the skin from external injuries, such as oxidative stress and microbial infections. Liposomes were prepared using biocompatible phospholipids dispersed in water. To improve vesicle stability and applicability, the phospholipids and the phenols were dispersed in water/propylene glycol or water/glycerol, thus obtaining PEVs and glycerosomes, respectively. The vesicles were characterized by size, morphology, physical stability, and their therapeutic efficacy was investigated in vitro. The vesicles were spherical, unilamellar and small in size: liposomes and glycerosomes were around 70nm in diameter, while PEVs were larger (∼170nm). The presence of propylene glycol or glycerol increased the viscosity of the vesicle systems, positively affecting their stability. The ability of the vesicles to promote the accumulation of the phenols (especially gallic acid) in the skin was demonstrated, as well as their low toxicity and great ability to protect keratinocytes and fibroblasts from oxidative damage. Additionally, an improvement of the antimicrobial activity of the phenols was shown against different skin pathogens. The co-loading of resveratrol and gallic acid in modified phospholipid vesicles represents an innovative, bifunctional tool for preventing and treating skin affections. Copyright © 2017 Elsevier B.V. All rights reserved.

Quantification of Training and Competition Loads in Endurance Sports: Methods and Applications.

PubMed

Mujika, Iñigo

2017-04-01

Training quantification is basic to evaluate an endurance athlete's responses to training loads, ensure adequate stress/recovery balance, and determine the relationship between training and performance. Quantifying both external and internal workload is important, because external workload does not measure the biological stress imposed by the exercise sessions. Generally used quantification methods include retrospective questionnaires, diaries, direct observation, and physiological monitoring, often based on the measurement of oxygen uptake, heart rate, and blood lactate concentration. Other methods in use in endurance sports include speed measurement and the measurement of power output, made possible by recent technological advances such as power meters in cycling and triathlon. Among subjective methods of quantification, rating of perceived exertion stands out because of its wide use. Concurrent assessments of the various quantification methods allow researchers and practitioners to evaluate stress/recovery balance, adjust individual training programs, and determine the relationships between external load, internal load, and athletes' performance. This brief review summarizes the most relevant external- and internal-workload-quantification methods in endurance sports and provides practical examples of their implementation to adjust the training programs of elite athletes in accordance with their individualized stress/recovery balance.

Could autonomous motivation hold the key to successfully implementing lifestyle changes in affective disorders? A multicentre cross sectional study.

PubMed

Vancampfort, Davy; Madou, Tomas; Moens, Herman; De Backer, Tanja; Vanhalst, Patrick; Helon, Chris; Naert, Pieter; Rosenbaum, Simon; Stubbs, Brendon; Probst, Michel

2015-07-30

There is a need for theoretically-based research on the motivational processes linked to the adoption and maintenance of an active lifestyle in people with affective disorders. Within the Self-Determination Theory (SDT) framework, we investigated the SDT tenets in people with major depressive disorder or bipolar disorder by examining the factor structure of the Behavioural Regulation in Exercise Questionnaire-2 (BREQ-2) and by investigating associations between motivation, the Positive and Negative Affect Scale (PANAS) and International Physical Activity Questionnaire (IPAQ) scores. A total of 165 patients (105 ♀) (45.6 ± 14.2 years) agreed to participate. An exploratory factor analysis demonstrated sufficient convergence with the original factor for amotivation, and external and introjected regulation. The items of identified and intrinsic regulation loaded on the same factor, which was labelled autonomous regulation. Significant correlations were found between the total IPAQ score and the subscales amotivation, external regulation, introjected regulation and autonomous regulation. The relative autonomy index (RAI) was associated with the PANAS scores. Differences in RAI were found between physically inactive and active participants. Our results suggest that in people with affective disorders the level of autonomous motivation may play an important role in the adoption and maintenance of health promoting behaviours. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Wellbeing perception and the impact on external training output among elite soccer players.

PubMed

Malone, Shane; Owen, Adam; Newton, Matt; Mendes, Bruno; Tiernan, Leo; Hughes, Brian; Collins, Kieran

2018-01-01

The objective of the investigation was to observe the impact of player wellbeing on the training output of elite soccer players. Prospective cohort design. Forty-eight soccer players (age: 25.3±3.1years; height: 183±7cm; mass: 72±7kg) were involved in this single season observational study across two teams. Each morning, pre-training, players completed customised perceived wellbeing questionnaires. Global positioning technology devices were used to measure external load (total distance, total high-speed running distance, high speed running, player load, player load slow, maximal velocity, maximal velocity exposures). Players reported ratings of perceived exertion using the modified Borg CR-10 scale. Integrated training load ratios were also analysed for total distance:RPE, total high speed distance:RPE player load:RPE and player load slow:RPE respectively. Mixed-effect linear models revealed significant effects of wellbeing Z-score on external and integrated training load measures. A wellbeing Z-score of -1 corresponded to a -18±2m (-3.5±1.1%), 4±1m (-4.9±2.1%,) 0.9±0.1kmh -1 (-3.1±2.1%), 1±1 (-4.6±2.9%), 25±3AU (-4.9±3.1%) and 11±0.5AU (-8.9±2.9%) reduction in total high speed distance, high speed distance, maximal velocity, maximal velocity exposures, player load and player load slow respectively. A reduction in wellbeing impacted external:internal training load ratios and resulted in -0.49±0.12mmin -1 , -1.20±0.08mmin -1 ,-0.02±0.01AUmin -1 in total distance:RPE, total high speed distance:RPE and player load slow:RPE respectively. The results suggest that systematic monitoring of player wellbeing within soccer cohorts can provide coaches with information about the training output that can be expected from individual players during a training session. Copyright © 2017 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

Patterning of alloy precipitation through external pressure

NASA Astrophysics Data System (ADS)

Franklin, Jack A.

Due to the nature of their microstructure, alloyed components have the benefit of meeting specific design goals across a wide range of electrical, thermal, and mechanical properties. In general by selecting the correct alloy system and applying a proper heat treatment it is possible to create a metallic sample whose properties achieve a unique set of design requirements. This dissertation presents an innovative processing technique intended to control both the location of formation and the growth rates of precipitates within metallic alloys in order to create multiple patterned areas of unique microstructure within a single sample. Specific experimental results for the Al-Cu alloy system will be shown. The control over precipitation is achieved by altering the conventional heat treatment process with an external surface load applied to selected locations during the quench and anneal. It is shown that the applied pressures affect both the rate and directionality of the atomic diffusion in regions close to the loaded surfaces. The control over growth rates is achieved by altering the enthalpic energy required for successful diffusion between lattice sites. Changes in the local chemical free energy required to direct the diffusion of atoms are established by introducing a non-uniform elastic strain energy field within the samples created by the patterned surface pressures. Either diffusion rates or atomic mobility can be selected as the dominating control process by varying the quench rate; with slower quenches having greater control over the mobility of the alloying elements. Results have shown control of Al2Cu precipitation over 100 microns on mechanically polished surfaces. Further experimental considerations presented will address consistency across sample ensembles. This includes repeatable pressure loading conditions and the chemical interaction between any furnace environments and both the alloy sample and metallic pressure loading devices.

Internal phosphorus loading across a cascade of three eutrophic basins: A synthesis of short- and long-term studies.

PubMed

Tammeorg, Olga; Horppila, Jukka; Tammeorg, Priit; Haldna, Marina; Niemistö, Juha

2016-12-01

Ascertaining the phosphorus (P) release processes in polymictic lakes is one of the methodologically most complex questions in limnology. In the current study, we combined short- and long-term investigations to elucidate the role of sediments in the P budget in a chain of eutrophic lake basins. We quantified the internal loading of P in three basins of Lake Peipsi (Estonia/Russia) for two periods characterized by different external P loadings using radiometrically dated sediment cores (long-term studies). The relationships between different water quality variables and the internal P loading, and the external P loading were studied. Our short-term studies aimed at elucidating the possible mechanisms behind variations in internal P loading included examination of the surficial sediments, i.e., seasonal measurements of redox potential, sediment pore water P concentrations and diffusive fluxes. Our results provided evidence for a potentially high importance of internal P loading in regulating water quality. The sediment core analyses revealed an increase in the internal P loading during the period of lower external P loading coinciding with the general deterioration in the lake water quality (i.e, higher concentrations of soluble reactive phosphorus, total phosphorus and biomass of cyanobacteria). Increase in wave action between the two studied periods appeared to cause more frequent sediment resuspension, and thus be the most likely reason for the variations in internal P loading. Our short-term measurements indicated that resuspension events can be followed by a considerable increase in the diffusive fluxes. Copyright © 2016 Elsevier B.V. All rights reserved.

Effect of ACL Transection on Internal Tibial Rotation in an in Vitro Simulated Pivot Landing

PubMed Central

Oh, Youkeun K.; Kreinbrink, Jennifer L.; Ashton-Miller, James A.; Wojtys, Edward M.

2011-01-01

Background: The amount of resistance provided by the ACL (anterior cruciate ligament) to axial tibial rotation remains controversial. The goal of this study was to test the primary hypotheses that ACL transection would not significantly affect tibial rotation under the large impulsive loads associated with a simulated pivot landing but would increase anterior tibial translation. Methods: Twelve cadaveric knees (mean age of donors [and standard deviation] at the time of death, 65.0 ± 10.5 years) were mounted in a custom testing apparatus to simulate a single-leg pivot landing. A compound impulsive load was applied to the distal part of the tibia with compression (∼800 N), flexion moment (∼40 N-m), and axial tibial torque (∼17 N-m) in the presence of five trans-knee muscle forces. A differential variable reluctance transducer mounted on the anteromedial aspect of the ACL measured relative strain. With the knee initially in 15° of flexion, and after five combined compression and flexion moment (baseline) loading trials, six trials were conducted with the addition of either internal or external tibial torque (internal or external loading), and then six baseline trials were performed. The ACL was then sectioned, six baseline trials were repeated, and then six trials of either the internal or the external loading condition, whichever had initially resulted in the larger relative ACL strain, were carried out. Tibiofemoral kinematics were measured optoelectronically. The results were analyzed with a nonparametric Wilcoxon signed-rank test. Results: Following ACL transection, the increase in the normalized internal tibial rotation was significant but small (0.7°/N-m ± 0.3°/N-m to 0.8°/N-m ± 0.3°/N-m, p = 0.012), while anterior tibial translation increased significantly (3.8 ± 2.9 to 7.0 ± 2.9 mm, p = 0.017). Conclusions: ACL transection leads to a small increase in internal tibial rotation, equivalent to a 13% decrease in the dynamic rotational resistance, under the large forces associated with a simulated pivot landing, but it leads to a significant increase in anterior tibial translation. Clinical Relevance: An ACL reconstruction that restores both ligament orientation and stiffness will provide major resistance to anterior tibial translation while providing minor resistance to axial tibial rotation. PMID:21325589

Watershed Modeling to Assess the Sensitivity of Streamflow, Nutrient, and Sediment Loads to Potential Climate Change and Urban Development in 20 U.S. Watersheds (External Review Draft)

EPA Science Inventory

EPA has released for independent external peer review and public comment a draft report titled, Watershed Modeling to Assess the Sensitivity of Streamflow, Nutrient, and Sediment Loads to Potential Climate Change and Urban Development in 20 U.S. Watersheds. This is a draft...

A loose bolt delays loading of Endeavour's external tank

NASA Technical Reports Server (NTRS)

2000-01-01

This loose bracket, observed hanging down from the side of the White Room at Launch Pad 39B, delayed loading of Endeavour's external tank by several hours to allow technicians to remove it. A 'U' bolt connects the bracket to a fire suppression water line attached to the exterior of the White Room. The loose bolt could have possibly created a debris hazard.

Symptom reporting in cancer patients: the role of negative affect and experienced social stigma.

PubMed

Koller, M; Kussman, J; Lorenz, W; Jenkins, M; Voss, M; Arens, E; Richter, E; Rothmund, M

1996-03-01

Recent research suggests that patients' appraisal of somatic symptoms is more closely related to emotional variables (particularly negative affect) than to their actual health as determined by external criteria. Sixty surgical cancer patients who at the time of a routine follow-up examination filled out the European Organization for Research and Treatment of Cancer (EORTC) quality of life questionnaire-C30, which included a positive/negative affect scale and a scale tapping into experienced social stigma. Patients' health status was determined in two ways: the examining physician gave a global judgement on a standardized scale at the end of the examination, and an additional two external physicians later rated the patients based on the findings listed in the medical record. Patients' reports of somatic symptoms were strongly correlated with two measures of negative affect (r = 0.75 and r = 0.65, respectively) and with experienced social stigma (r = 0.51). In contrast, the correlations between reported symptoms and the examining or external physicians' ratings were considerably weaker (r = 0.31 and r = 0.19). According to a multiple linear regression with 6 predictors, negative affect was the best single predictor of symptom reporting (beta = 0.68; P < 0.001) and global quality of life (beta = 0.48; P < 0.001). Factor analysis yielded a dimension of somatopsychosocial distress that accounted for 44.1% of the variance and is comprised of reported symptoms (factor loading = 0.86), negative affect (0.90 and 0.82), experienced social stigma (0.74), and global quality of life (0.70). Physicians' ratings and positive affect constituted two additional separate factors. Cancer patients' reporting of somatic symptoms by means of a standardized quality of life questionnaire is closely related to emotional and social distress and is not equivalent to health status as determined from a clinical perspective. Researchers and practitioners have to be aware of this fact when interpreting quality of life data. Furthermore, negative affect deserves attention as an important signal for intervention in tumor follow-up programs.

Influence of the height of the external hexagon and surface treatment on fatigue life of commercially pure titanium dental implants.

PubMed

Gil, Francisco Javier; Aparicio, Conrado; Manero, Jose M; Padros, Alejandro

2009-01-01

This study evaluated the effect of external hexagon height and commonly applied surface treatments on the fatigue life of titanium dental implants. Electropolished commercially pure titanium dental implants (seven implants per group) with three different external hexagon heights (0.6, 1.2, and 1.8 mm) and implants with the highest external hexagon height (1.8 mm) and different surface treatments (electropolishing, grit blasting with aluminium oxide, and acid etching with sulfuric acid) were tested to evaluate their mechanical fatigue life. To do so, 10-Hz triangular flexural load cycles were applied at 37 degrees C in artificial saliva, and the number of load cycles until implant fracture was determined. Tolerances of the hexagon/abutment fit and implant surface roughness were analyzed by scanning electron microscopy and light interferometry. Transmission electron microscopy and electron diffraction analyses of titanium hydrides were performed. First, the fatigue life of implants with the highest hexagon (8,683 +/- 978 load cycles) was more than double that of the implants with the shortest hexagons (3,654 +/- 789 load cycles) (P < .02). Second, the grit-blasted implants had the longest fatigue life of the tested materials (21,393 +/- 2,356 load cycles), which was significantly greater than that of the other surfaces (P < .001). The compressive surface residual stresses induced when blasting titanium are responsible for this superior mechanical response. Third, precipitation of titanium hydrides in grain boundaries of titanium caused by hydrogen adsorption from the acid solution deteriorates the fatigue life of acid-etched titanium dental implants. These implants had the shortest fatigue life (P < .05). The fatigue life of threaded root-form dental implants varies with the height of the external hexagon and/or the surface treatment of the implant. An external hexagon height of 1.8 mm and/or a blasting treatment appear to significantly increase fatigue life of dental implants.

Internal cycling, not external loading, decides the nutrient limitation in eutrophic lake: A dynamic model with temporal Bayesian hierarchical inference.

PubMed

Wu, Zhen; Liu, Yong; Liang, Zhongyao; Wu, Sifeng; Guo, Huaicheng

2017-06-01

Lake eutrophication is associated with excessive anthropogenic nutrients (mainly nitrogen (N) and phosphorus (P)) and unobserved internal nutrient cycling. Despite the advances in understanding the role of external loadings, the contribution of internal nutrient cycling is still an open question. A dynamic mass-balance model was developed to simulate and measure the contributions of internal cycling and external loading. It was based on the temporal Bayesian Hierarchical Framework (BHM), where we explored the seasonal patterns in the dynamics of nutrient cycling processes and the limitation of N and P on phytoplankton growth in hyper-eutrophic Lake Dianchi, China. The dynamic patterns of the five state variables (Chla, TP, ammonia, nitrate and organic N) were simulated based on the model. Five parameters (algae growth rate, sediment exchange rate of N and P, nitrification rate and denitrification rate) were estimated based on BHM. The model provided a good fit to observations. Our model results highlighted the role of internal cycling of N and P in Lake Dianchi. The internal cycling processes contributed more than external loading to the N and P changes in the water column. Further insights into the nutrient limitation analysis indicated that the sediment exchange of P determined the P limitation. Allowing for the contribution of denitrification to N removal, N was the more limiting nutrient in most of the time, however, P was the more important nutrient for eutrophication management. For Lake Dianchi, it would not be possible to recover solely by reducing the external watershed nutrient load; the mechanisms of internal cycling should also be considered as an approach to inhibit the release of sediments and to enhance denitrification. Copyright © 2017 Elsevier Ltd. All rights reserved.

In situ forces and length patterns of the fibular collateral ligament under controlled loading: an in vitro biomechanical study using a robotic system.

PubMed

Liu, Ping; Wang, Jianquan; Xu, Yan; Ao, Yingfang

2015-04-01

The aim of this study was to determine the in situ forces and length patterns of the fibular collateral ligament (FCL) and kinematics of the knee under various loading conditions. Six fresh-frozen cadaveric knees were used (mean age 46 ± 14.4 years; range 20-58). In situ forces and length patterns of FCL and kinematics of the knee were determined under the following loading conditions using a robotic/universal force-moment sensor testing system: no rotation, varus (10 Nm), external rotation (5 Nm), and internal rotation (5 Nm) at 0°, 15°, 30°, 60º, 90°, and 120° of flexion, respectively. Under no rotation loading, the distances between the centres of the FCL attachments decreased as the knee flexed. Under varus loading, the force in FCL peaked at 15° of flexion and decreased with further knee flexion, while distances remained nearly constant and the varus rotation increased with knee flexion. Using external rotation, the force in the FCL also peaked at 15° flexion and decreased with further knee flexion, the distances decreased with flexion, and external rotation increased with knee flexion. Using internal rotation load, the force in the FCL was relatively small across all knee flexion angles, and the distances decreased with flexion; the amount of internal rotation was fairly constant. FCL has a primary role in preventing varus and external rotation at 15° of flexion. The FCL does not perform isometrically following knee flexion during neutral rotation, and tibia rotation has significant effects on the kinematics of the FCL. Varus and external rotation laxity increased following knee flexion. By providing more realistic data about the function and length patterns of the FCL and the kinematics of the intact knee, improved reconstruction and rehabilitation protocols can be developed.

Space Shuttle Projects

NASA Image and Video Library

1987-07-01

A forward segment is being lowered into the Transient Pressure Test Article (TPTA) test stand at the Marshall Space Flight Center (MSFC) east test area. The TPTA test stand, 14-feet wide, 27-feet long, and 33-feet high, was built in 1987 to provide data to verify the sealing capability of the redesign solid rocket motor (SRM) field and nozzle joints. The test facility applies pressure, temperature, and external loads to a short stack of solid rocket motor hardware. The simulated SRM ignition pressure and temperature transients are achieved by firing a small amount of specially configured solid propellant. The pressure transient is synchronized with external programmable dynamic loads that simulate lift off loads at the external tank attach points. Approximately one million pounds of dead weight on top of the test article simulates the weight of the other Shuttle elements.

Space Shuttle Projects

NASA Image and Video Library

1987-07-01

A forward segment is being lowered into the Transient Pressure Test Article (TPTA) test stand at thw Marshall Space Flight Center (MSFC) east test area. The TPTA test stand, 14-feet wide, 27-feet long, and 33-feet high, was built in 1987 to provide data to verify the sealing capability of the redesign solid rocket motor (SRM) field and nozzle joints. The test facility applies pressure, temperature, and external loads to a short stack of solid rocket motor hardware. The simulated SRM ignition pressure and temperature transients are achieved by firing a small amount of specially configured solid propellant. The pressure transient is synchronized with external programmable dynamic loads that simulate lift off loads at the external tank attach points. Approximately one million pounds of dead weight on top of the test article simulates the weight of the other Shuttle elements.

Environmental And Quality Management System In The Context Of Sustainable Development

NASA Astrophysics Data System (ADS)

Rusko, Miroslav

2015-06-01

Growing load and deterioration of the environment can be interpreted as a result of some external effects interventions. While the positive externalities influence the positive productional and utilizational functions of other subjects, the negative externalities influence the negative ones. Both types of external effects can act as parcial or global externalities. Linking of environmental issues to economy and finance is an important sphere.

Evidence for the role of a Na(+)/HCO(3)(-) cotransporter in trout hepatocyte pHi regulation.

PubMed

Furimsky, M; Moon, T W; Perry, S F

2000-07-01

The mechanisms of intracellular pH (pHi) regulation were examined in hepatocytes of the rainbow trout Oncorhynchus mykiss. pHi was monitored using the pH-sensitive fluorescent dye BCECF, and the effects of various media and pharmacological agents were examined for their influence on baseline pHi and recovery rates from acid and base loading. Rates of Na(+) uptake were measured using (22)Na, and changes in membrane potential were examined using the potentiometric fluorescent dye Oxonol VI. The rate of proton extrusion following acid loading was diminished by the blockade of either Na(+)/H(+) exchange (using amiloride) or anion transport (using DIDS). The removal of external HCO(3)(-) and the abolition of outward K(+) diffusion by the channel blocker Ba(2+) also decreased the rate of proton extrusion following acid load. Depolarization of the cell membrane with 50 mmol l(-)(1) K(+), however, did not affect pHi. The rate of recovery from base loading was significantly diminished by the blockade of anion transport, removal of external HCO(3)(-) and, to a lesser extent, by blocking Na(+)/H(+) exchange. The blockade of K(+) conductance had no effect. The decrease in Na(+) uptake rate observed in the presence of the anion transport blocker DIDS and the DIDS-sensitive hyperpolarization of membrane potential during recovery from acid loading suggest that a Na(+)-dependent electrogenic transport system is involved in the restoration of pHi after intracellular acidification. The effects on baseline pHi indicate that the different membrane exchangers are tonically active in the maintenance of steady-state pHi. This study confirms the roles of a Na(+)/H(+) exchanger and a Cl(-)/HCO(3)(-) exchanger in the regulation of trout hepatocyte pHi and provides new evidence that a Na(+)/HCO(3)(-) cotransporter contributes to pHi regulation.

A Hydrostatic Bearing Test System for Measuring Bearing Load Using Magnetic-Fluid Lubricants.

PubMed

Weng, Huei Chu; Chen, Lu-Yu

2016-05-01

This paper conducts a study on the design of a hydrostatic bearing test system. It involves the determination of viscous properties of magnetic-fluid lubricants. The load of a hydrostatic thrust bearing using a water-based magnetite nanofluid of varying volume flow rate is measured under an applied external induction field via the test system. Results reveal that the presence of nanoparticles in a carrier liquid would cause an enhanced bearing load. Such an effect could be further magnified by increasing the lubricant volume flow rate or the external induction field strength.

A loose bolt delays loading of Endeavour's external tank

NASA Technical Reports Server (NTRS)

2000-01-01

A closeup reveals the loose bracket, observed hanging down from the side of the White Room at Launch Pad 39B, that delayed loading of Endeavour's external tank by several hours to allow technicians to remove it. A 'U' bolt connects the bracket to a fire suppression water line attached to the exterior of the White Room. The loose bolt could have possibly created a debris hazard.

Static-stress analysis of dual-axis safety vessel

NASA Astrophysics Data System (ADS)

Bultman, D. H.

1992-11-01

An 8 ft diameter safety vessel, made of HSLA-100 steel, is evaluated to determine its ability to contain the quasi-static residual pressure from a high explosive (HE) blast. The safety vessel is designed for use with the Dual-Axis Radiographic Hydrotest (DARHT) facility being developed at Los Alamos National Laboratory. A smaller confinement vessel fits inside the safety vessel and contains the actual explosion, and the safety vessel functions as a second layer of containment in the unlikely case of a confinement vessel leak. The safety vessel is analyzed as a pressure vessel based on the ASME Boiler and Pressure Vessel Code, Section 8, Division 1, and the Welding Research Council Bulletin, WRC107. Combined stresses that result from internal pressure and external loads on nozzles are calculated and compared to the allowable stresses for HSLA-100 steel. Results confirm that the shell and nozzle components are adequately designed for a static pressure of 830 psi, plus the maximum expected external loads. Shell stresses at the 'shell to nozzle' interface, produced from external loads on the nozzles, were less than 700 psi. The maximum combined stress resulting from the internal pressure plus external loads was 17,384 psi, which is significantly less than the allowable stress of 42,375 psi for HSLA-100 steel.

Relative importance of expertise, lifting height and weight lifted on posture and lumbar external loading during a transfer task in manual material handling.

PubMed

Plamondon, André; Larivière, Christian; Delisle, Alain; Denis, Denys; Gagnon, Denis

2012-01-01

The objective of this study was to measure the effect size of three important factors in manual material handling, namely expertise, lifting height and weight lifted. The effect of expertise was evaluated by contrasting 15 expert and 15 novice handlers, the effect of the weight lifted with a 15-kg box and a 23-kg box and the effect of lifting height with two different box heights: ground level and a 32 cm height. The task consisted of transferring a series of boxes from a conveyor to a hand trolley. Lifting height and weight lifted had more effect size than expertise on external back loading variables (moments) while expertise had low impact. On the other hand, expertise showed a significant effect of posture variables on the lumbar spine and knees. All three factors are important, but for a reduction of external back loading, the focus should be on the lifting height and weight lifted. The objective was to measure the effect size of three important factors in a transfer of boxes from a conveyor to a hand trolley. Lifting height and weight lifted had more effect size than expertise on external back loading variables but expertise was a major determinant in back posture.

External fixation using locking plate in distal tibial fracture: a finite element analysis.

PubMed

Zhang, Jingwei; Ebraheim, Nabil; Li, Ming; He, Xianfeng; Schwind, Joshua; Liu, Jiayong; Zhu, Limei

2015-08-01

External fixation of tibial fractures using a locking plate has been reported with favorable results in some selected patients. However, the stability of external plate fixation in this fracture pattern has not been previously demonstrated. We investigated the stability of external plate fixation with different plate-bone distances. In this study, the computational processing model of external fixation of a distal tibial metaphyseal fracture utilizing the contralateral femoral less invasive stabilization system plate was analyzed. The plate was placed on the anteromedial aspect of tibia with different plate-bone distances: 1, 10, 20, and 30 mm. Under axial load, the stiffness of construct in all groups was higher than intact tibia. Under axial load with an internal rotational force, the stiffness of construct with 1 and 10 mm plate-bone distances was similar to that of an intact tibia and the stiffness of the construct with 20 and 30 mm distances was lower than that of an intact tibia. Under axial load with an external rotational force, the stiffness of the construct in all groups was lower than that of an intact tibia. The maximum plate stresses were concentrated at the two most distal screws and were highest in the construct with the 10 mm plate-bone distance, and least in the construct with a 1 mm plate-bone distance. To guarantee a stable external plate fixation in distal tibial fracture, the plate-bone distance should be less than 30 mm.

Enhanced hydrolysis of cellulose hydrogels by morphological modification.

PubMed

Alfassi, Gilad; Rein, Dmitry M; Cohen, Yachin

2017-11-01

Cellulose is one of the most abundant bio-renewable materials on earth, yet the potential of cellulosic bio-fuels is not fully exploited, primarily due to the high costs of conversion. Hydrogel particles of regenerated cellulose constitute a useful substrate for enzymatic hydrolysis, due to their porous and amorphous structure. This article describes the influence of several structural aspects of the cellulose hydrogel on its hydrolysis. The hydrogel density was shown to be directly proportional to the cellulose concentration in the initial solution, thus affecting its hydrolysis rate. Using high-resolution scanning electron microscopy, we show that the hydrogel particles in aqueous suspension exhibit a dense external surface layer and a more porous internal network. Elimination of the external surface layer accelerated the hydrolysis rate by up to sixfold and rendered the process nearly independent of cellulose concentration. These findings may be of practical relevance to saccharification processing costs, by reducing required solvent quantities and enzyme load.

Identifying interactive effects of task demands in lifting on estimates of in vivo low back joint loads.

PubMed

Gooyers, Chad E; Beach, Tyson A C; Frost, David M; Howarth, Samuel J; Callaghan, Jack P

2018-02-01

This investigation examined interactions between the magnitude of external load, movement speed and (a)symmetry of load placement on estimates of in vivo joint loading in the lumbar spine during simulated occupational lifting. Thirty-two participants with manual materials handling experience were included in the study. Three-dimensional motion data, ground reaction forces, and activation of six bilateral trunk muscle groups were captured while participants performed lifts with two loads at two movement speeds and using two load locations. L4-L5 joint compression and shear force-time histories were estimated using an EMG-assisted musculoskeletal model of the lumbar spine. Results from this investigation provide strong evidence that known mechanical low back injury risk factors should not be viewed in isolation. Rather, injury prevention efforts need to consider the complex interactions that exist between external task demands and their combined influence on internal joint loading. Copyright © 2017 Elsevier Ltd. All rights reserved.

A fractal image analysis methodology for heat damage inspection in carbon fiber reinforced composites

NASA Astrophysics Data System (ADS)

Haridas, Aswin; Crivoi, Alexandru; Prabhathan, P.; Chan, Kelvin; Murukeshan, V. M.

2017-06-01

The use of carbon fiber-reinforced polymer (CFRP) composite materials in the aerospace industry have far improved the load carrying properties and the design flexibility of aircraft structures. A high strength to weight ratio, low thermal conductivity, and a low thermal expansion coefficient gives it an edge for applications demanding stringent loading conditions. Specifically, this paper focuses on the behavior of CFRP composites under stringent thermal loads. The properties of composites are largely affected by external thermal loads, especially when the loads are beyond the glass temperature, Tg, of the composite. Beyond this, the composites are subject to prominent changes in mechanical and thermal properties which may further lead to material decomposition. Furthermore, thermal damage formation being chaotic, a strict dimension cannot be associated with the formed damage. In this context, this paper focuses on comparing multiple speckle image analysis algorithms to effectively characterize the formed thermal damages on the CFRP specimen. This would provide us with a fast method for quantifying the extent of heat damage in carbon composites, thus reducing the required time for inspection. The image analysis methods used for the comparison include fractal dimensional analysis of the formed speckle pattern and analysis of number and size of various connecting elements in the binary image.

Efficient vibration mode analysis of aircraft with multiple external store configurations

NASA Technical Reports Server (NTRS)

Karpel, M.

1988-01-01

A coupling method for efficient vibration mode analysis of aircraft with multiple external store configurations is presented. A set of low-frequency vibration modes, including rigid-body modes, represent the aircraft. Each external store is represented by its vibration modes with clamped boundary conditions, and by its rigid-body inertial properties. The aircraft modes are obtained from a finite-element model loaded by dummy rigid external stores with fictitious masses. The coupling procedure unloads the dummy stores and loads the actual stores instead. The analytical development is presented, the effects of the fictitious mass magnitudes are discussed, and a numerical example is given for a combat aircraft with external wing stores. Comparison with vibration modes obtained by a direct (full-size) eigensolution shows very accurate coupling results. Once the aircraft and stores data bases are constructed, the computer time for analyzing any external store configuration is two to three orders of magnitude less than that of a direct solution.

3-Chloro-1,2-propanediol biodegradation by Ca-alginate immobilized Pseudomonas putida DSM 437 cells applying different processes: mass transfer effects.

PubMed

Konti, Aikaterini; Mamma, Diomi; Hatzinikolaou, Dimitios G; Kekos, Dimitris

2016-10-01

3-Chloro-1,2-propanediol (3-CPD) biodegradation by Ca-alginate immobilized Pseudomonas putida cells was performed in batch system, continuous stirred tank reactor (CSTR), and packed-bed reactor (PBR). Batch system exhibited higher biodegradation rates and 3-CPD uptakes compared to CSTR and PBR. The two continuous systems (CSTR and PBR) when compared at 200 mg/L 3-CPD in the inlet exhibited the same removal of 3-CPD at steady state. External mass-transfer limitations are found negligible at all systems examined, since the observable modulus for external mass transfer Ω ≪ 1 and the Biot number Bi > 1. Intra-particle diffusion resistance had a significant effect on 3-CPD biodegradation in all systems studied, but to a different extent. Thiele modulus was in the range of 2.5 in batch system, but it was increased at 11 when increasing cell loading in the beads, thus lowering significantly the respective effectiveness factor. Comparing the systems at the same cell loading in the beads PBR was less affected by internal diffusional limitations compared to CSTR and batch system, and, as a result, exhibited the highest overall effectiveness factor.

Ankle Joint Contact Loads and Displacement With Progressive Syndesmotic Injury.

PubMed

Hunt, Kenneth J; Goeb, Yannick; Behn, Anthony W; Criswell, Braden; Chou, Loretta

2015-09-01

Ligamentous injuries to the distal tibiofibular syndesmosis are predictive of long-term ankle dysfunction. Mild and moderate syndesmotic injuries are difficult to stratify, and the impact of syndesmosis injury on the magnitude and distribution of forces within the ankle joint during athletic activities is unknown. Eight below-knee cadaveric specimens were tested in the intact state and after sequential sectioning of the following ligaments: anterior-inferior tibiofibular, anterior deltoid (1 cm), interosseous/transverse (IOL/TL), posterior-inferior tibiofibular, and whole deltoid. In each condition, specimens were loaded in axial compression to 700 N and then externally rotated to 20 N·m torque. During axial loading and external rotation, both the fibula and the talus rotated significantly after each ligament sectioning as compared to the intact condition. After IOL/TL release, a significant increase in posterior translation of the fibula was observed, although no syndesmotic widening was observed. Mean tibiotalar contact pressure increased significantly after IOL/TL release, and the center of pressure shifted posterolaterally, relative to more stable conditions, after IOL/TL release. There were significant increases in mean contact pressure and peak pressure along with a reduction in contact area with axial loading and external rotation as compared to axial loading alone for all 5 conditions. Significant increases in tibiotalar contact pressures occur when external rotation stresses are added to axial loading. Moderate and severe injuries are associated with a significant increase in mean contact pressure combined with a shift in the center of pressure and rotation of the fibula and talus. Considerable changes in ankle joint kinematics and contact mechanics may explain why moderate syndesmosis injuries take longer to heal and are more likely to develop long-term dysfunction and, potentially, ankle arthritis. © The Author(s) 2015.

Synchronization of distributed power grids with the external loading system

NASA Astrophysics Data System (ADS)

Wei, Duqu; Mei, Chuncao

2018-06-01

In this paper, the synchronization between spatially distributed power plants and their supported consumers is studied, where the case of Kuramoto-like model power grids connected to an external permanent magnet synchronous motor (PMSM) is taken as an example. We focus on the dependence of the synchronization on the coupling coefficient. To quantitatively study the synchronization degree, we introduce the order parameter and the frequency deviation to measure the synchronization of the coupled system. It is found that as the external coupling coefficient is increased, the distributed power grids and the loading system become more and more synchronized in space, and the complete synchronization appears at a particular value of external coupling coefficient. Our results may provide a useful tip for analyzing the synchronous ability of distributed power grids.

Design and implementation of an external quality assessment program for HIV viral load measurements using dried blood spots.

PubMed

Prach, Lisa M; Puren, Adrian; Lippman, Sheri A; Carmona, Sergio; Stephenson, Sophie; Cutler, Ewalde; Barnhart, Scott; Liegler, Teri

2015-03-01

An external quality assurance program was developed for HIV-1 RNA viral load measurements taken from dried blood spots using a reference panel and field-collected specimens. The program demonstrated that accurate and reproducible quantitation can be obtained from field-collected specimens. Residual proviral DNA may confound interpretation in virologically suppressed subjects. Copyright © 2015, American Society for Microbiology. All Rights Reserved.

Transient Reactivation of a Deep-Seated Landslide by Undrained Loading Captured With Repeat Airborne and Terrestrial Lidar

NASA Astrophysics Data System (ADS)

Booth, Adam M.; McCarley, Justin; Hinkle, Jason; Shaw, Susan; Ampuero, Jean-Paul; Lamb, Michael P.

2018-05-01

Landslides reactivate due to external environmental forcing or internal mass redistribution, but the process is rarely documented quantitatively. We capture the three-dimensional, 1-m resolution surface deformation field of a transiently reactivated landslide with image correlation of repeat airborne lidar. Undrained loading by two debris flows in the landslide's head, rather than external forcing, triggered reactivation. After that loading, the lower 2 km of the landslide advanced by up to 14 m in 2 years before completely stopping. The displacement field over those 2 years implies that the slip surface gained 1 kPa of shear strength, which was likely accomplished by a negative dilatancy-pore pressure feedback as material deformed around basal roughness elements. Thus, landslide motion can be decoupled from external environmental forcing in cases, motivating the need to better understand internal perturbations to the stress field to predict hazards and sediment fluxes as landscapes evolve.

A theoretical derivation of the dilatancy equation for brittle rocks based on Maxwell model

NASA Astrophysics Data System (ADS)

Li, Jie; Huang, Houxu; Wang, Mingyang

2017-03-01

In this paper, the micro-cracks in the brittle rocks are assumed to be penny shaped and evenly distributed; the damage and dilatancy of the brittle rocks is attributed to the growth and expansion of numerous micro-cracks under the local tensile stress. A single crack's behaviour under the local tensile stress is generalized to all cracks based on the distributed damage mechanics. The relationship between the local tensile stress and the external loading is derived based on the Maxwell model. The damage factor corresponding to the external loading is represented using the p-alpha ( p- α) model. A dilatancy equation that can build up a link between the external loading and the rock dilatancy is established. A test of dilatancy of a brittle rock under triaxial compression is conducted; the comparison between experimental results and our theoretical results shows good consistency.

Response in the water quality of the Salton Sea, California, to changes in phosphorus loading: An empirical modeling approach

USGS Publications Warehouse

Robertson, Dale M.; Schladow, S.G.

2008-01-01

Salton Sea, California, like many other lakes, has become eutrophic because of excessive nutrient loading, primarily phosphorus (P). A Total Maximum Daily Load (TMDL) is being prepared for P to reduce the input of P to the Sea. In order to better understand how P-load reductions should affect the average annual water quality of this terminal saline lake, three different eutrophication programs (BATHTUB, WiLMS, and the Seepage Lake Model) were applied. After verifying that specific empirical models within these programs were applicable to this saline lake, each model was calibrated using water-quality and nutrient-loading data for 1999 and then used to simulate the effects of specific P-load reductions. Model simulations indicate that a 50% decrease in external P loading would decrease near-surface total phosphorus concentrations (TP) by 25-50%. Application of other empirical models demonstrated that this decrease in loading should decrease near-surface chlorophyll a concentrations (Chl a) by 17-63% and increase Secchi depths (SD) by 38-97%. The wide range in estimated responses in Chl a and SD were primarily caused by uncertainty in how non-algal turbidity would respond to P-load reductions. If only the models most applicable to the Salton Sea are considered, a 70-90% P-load reduction is required for the Sea to be classified as moderately eutrophic (trophic state index of 55). These models simulate steady-state conditions in the Sea; therefore, it is difficult to ascertain how long it would take for the simulated changes to occur after load reductions. ?? 2008 Springer Science+Business Media B.V.

An analytical study of the effects of transverse shear deformation and anisotropy on buckling loads of laminated cylinders. M.S. Thesis - George Washington Univ.

NASA Technical Reports Server (NTRS)

Jegley, Dawn C.

1987-01-01

Buckling loads of thick-walled orthotropic and anisotropic simply supported circular cylinders are predicted using a higher-order transverse-shear deformation theory. A comparison of buckling loads predicted by the conventional first-order transverse-shear deformation theory and the higher-order theory show that the additional allowance for transverse shear deformation has a negligible effect on the predicted buckling loads of medium-thick metallic isotropic cylinders. However, the higher-order theory predicts buckling loads which are significantly lower than those predicted by the first-order transverse-shear deformation theory for certain short, thick-walled cylinders which have low through-the-thickness shear moduli. A parametric study of the effects of ply orientation on the buckling load of axially compressed cylinders indicates that laminates containing 45 degree plies are most sensitive to transverse-shear deformation effects. Interaction curves for buckling loads of cylinders subjected to axial compressive and external pressure loadings indicate that buckling loads due to external pressure loadings are as sensitive to transverse-shear deformation effects as buckling loads due to axial compressive loadings. The effects of anisotropy are important over a much wider range of cylinder geometries than the effects of transverse shear deformation.

Disrupted resting brain graph measures in individuals at high risk for alcoholism.

PubMed

Holla, Bharath; Panda, Rajanikant; Venkatasubramanian, Ganesan; Biswal, Bharat; Bharath, Rose Dawn; Benegal, Vivek

2017-07-30

Familial susceptibility to alcoholism is likely to be linked to the externalizing diathesis seen in high-risk offspring from high-density alcohol use disorder (AUD) families. The present study aimed at comparing resting brain functional connectivity and their association with externalizing symptoms and alcoholism familial density in 40 substance-naive high-risk (HR) male offspring from high-density AUD families and 30 matched healthy low-risk (LR) males without a family history of substance dependence using graph theory-based network analysis. The HR subjects from high-density AUD families compared with LR, showed significantly reduced clustering, small-worldness, and local network efficiency. The frontoparietal, cingulo-opercular, sensorimotor and cerebellar networks exhibited significantly reduced functional segregation. These disruptions exhibited independent incremental value in predicting the externalizing symptoms over and above the demographic variables. The reduction of functional segregation in HR subjects was significant across both the younger and older age groups and was proportional to the family loading of AUDs. Detection and estimation of these developmentally relevant disruptions in small-world architecture at critical brain regions sub-serving cognitive, affective, and sensorimotor processes are vital for understanding the familial risk for early onset alcoholism as well as for understanding the pathophysiological mechanism of externalizing behaviors. Copyright © 2017 Elsevier Ireland Ltd. All rights reserved.

Dramatic effects of external alkalinity on neuronal calcium recovery following a short-duration glutamate challenge: the role of the plasma membrane Ca2+/H+ pump.

PubMed

Khodorov, B; Pinelis, V; Vergun, O; Storozhevykh, T; Fajuk, D; Vinskaya, N; Arsenjeva, E; Khaspekov, L; Lyzin, A; Isaev, N

1995-09-11

Alkalinization of the external medium has been shown to suppress Ca2+ extrusion from neurons due to inhibition of the plasmalemmal Ca2+/H+ pump. In our experiments on fura-2-loaded rat cerebellar granule cells and mouse hippocampal neurons, an increase in pHo from 7.4 to 8.5 following a 1-min glutamate or NMDA challenge caused a dramatic delay in [Ca2+]i recovery which in some cases was accompanied by an additional increase in [Ca2+]i. Normalization of pHo, or removal of Ca2+ from the alkaline solution allowed [Ca2+]i to decrease rapidly again. External alkalinity did not affect the initial rapid decline in [Ca2+]i following a 25 mMK+ pulse. In cerebellar granule cells, the alkaline pHo considerably increased the 45Ca2+ uptake both at rest and following a 2-min GLU pulse. A comparison of these effects of alkaline pHo with those produced by removal of the external Na+ led us to conclude that the Ca2+/H+ pump plays a dominant role in the mechanism of the fast Ca2+ extrusion from glutamate- or NMDA-treated neurons.

Kinematic evaluation of patients with total and reverse shoulder arthroplasty during rehabilitation exercises with different loads.

PubMed

de Toledo, Joelly Mahnic; Loss, Jefferson Fagundes; Janssen, Thomas W; van der Scheer, Jan W; Alta, Tjarco D; Willems, W Jaap; Veeger, DirkJan H E J

2012-10-01

Following shoulder arthroplasty, any well-planned rehabilitation program should include muscle strengthening. However, it is not always clear how different external loads influence shoulder kinematics in patients with shoulder prostheses. The objective of this study was to describe shoulder kinematics and determine the contribution of the scapulothoracic joint to total shoulder motion of patients with total and reverse shoulder arthroplasties and of healthy individuals during rehabilitation exercises (anteflexion and elevation in the scapular plane) using different loading conditions (without external load, 1 kg and elastic resistance). Shoulder motions were measured using an electromagnetic tracking device. A force transducer was used to record force signals during loaded conditions using elastic resistance. Statistical comparisons were made using a three-way repeated-measures analysis of variance with a Bonferroni post hoc testing. The scapula contributed more to movement of the arm in subjects with prostheses compared to healthy subjects. The same applies for loaded conditions (1 kg and elastic resistance) relative to unloaded tasks. For scapular internal rotation, upward rotation and posterior tilt no significant differences among groups were found during both exercises. Glenohumeral elevation angles during anteflexion were significantly higher in the total shoulder arthroplasty group compared to the reverse shoulder arthroplasty group. Differences in contribution of the scapula to total shoulder motion between patients with different types of arthroplasties were not significant. However, compared to healthy subjects, they were. Furthermore, scapular kinematics of patients with shoulder arthroplasty was influenced by implementation of external loads, but not by the type of load. Copyright © 2012 Elsevier Ltd. All rights reserved.

Time Course of Peri-Implant Bone Regeneration around Loaded and Unloaded Implants in a Rat Model

PubMed Central

Jariwala, Shailly H.; Wee, Hwabok; Roush, Evan P.; Whitcomb, Tiffany L.; Murter, Christopher; Kozlansky, Gery; Lakhtakia, Akhlesh; Kunselman, Allen R.; Donahue, Henry J.; Armstrong, April D.; Lewis, Gregory S.

2018-01-01

The time-course of cancellous bone regeneration surrounding mechanically loaded implants affects implant fixation, and is relevant to determining optimal rehabilitation protocols following orthopaedic surgeries. We investigated the influence of controlled mechanical loading of titanium-coated polyether-ether ketone (PEEK) implants on osseointegration using time-lapsed, non-invasive, in vivo micro-computed tomography (micro-CT) scans. Implants were inserted into proximal tibial metaphyses of both limbs of eight female Sprague-Dawley rats. External cyclic loading (60 μm or 100 μm displacement, 1 Hz, 60 seconds) was applied every other day for 14 days to one implant in each rat, while implants in contralateral limbs served as the unloaded controls. Hind limbs were imaged with high-resolution micro-CT (12.5 μm voxel size) at 2, 5, 9, and 12 days post-surgery. Trabecular changes over time were detected by 3D image registration allowing for measurements of bone-formation rate (BFR) and bone-resorption rate (BRR). At day 9, mean %BV/TV for loaded and unloaded limbs were 35.5 ± 10.0 % and 37.2 ± 10.0 %, respectively, and demonstrated significant increases in bone volume compared to day 2. BRR increased significantly after day 9. No significant differences between bone volumes, BFR, and BRR were detected due to implant loading. Although not reaching significance (p = 0.16), an average 119 % increase in pull-out strength was measured in the loaded implants. PMID:27381807

The effects of transverse rotation angle on compression and effective lever arm of prosthetic feet during simulated stance.

PubMed

Major, Matthew J; Howard, David; Jones, Rebecca; Twiste, Martin

2012-06-01

Unlike sagittal plane prosthesis alignment, few studies have observed the effects of transverse plane alignment on gait and prosthesis behaviour. Changes in transverse plane rotation angle will rotate the points of loading on the prosthesis during stance and may alter its mechanical behaviour. This study observed the effects of increasing the external transverse plane rotation angle, or toe-out, on foot compression and effective lever arm of three commonly prescribed prosthetic feet. The roll-over shape of a SACH, Flex and single-axis foot was measured at four external rotation angle conditions (0°, 5°, 7° and 12° relative to neutral). Differences in foot compression between conditions were measured as average distance between roll-over shapes. Increasing the transverse plane rotation angle did not affect foot compression. However, it did affect the effective lever arm, which was maximized with the 5° condition, although differences between conditions were small. Increasing the transverse plane rotation angle of prosthetic feet by up to 12° beyond neutral has minimal effects on their mechanical behaviour in the plane of walking progression during weight-bearing.

Ring stability of underground toroidal tanks

NASA Astrophysics Data System (ADS)

Lubis, Asnawi; Su'udi, Ahmad

2017-06-01

The design of pressure vessels subjected to internal pressure is governed by its strength, while the design of pressure vessels subjected to external pressure is governed by its stability, which is for circular cross-section is called the ring stability. This paper presented the results of finite element study of ring stability of circular toroidal tank without stiffener under external pressure. The tank was placed underground and external pressure load from soil was simulated as pressure at the top of the vessel along 30° circumferentially. One might ask the reason for choosing toroidal rather than cylindrical tank. Preliminary finite element studies showed that toroidal shells can withstand higher external pressure than cylindrical shells. In this study, the volume of the tank was fixed for 15,000 litters. The buckling external pressure (pL) was calculated for radius ratio (R/r) of 2, 3, and 4. The corresponding cross-section radiuses were 724.3 mm, 632.7 mm, and 574.9 mm, respectively. The selected element type was SHELL 281 from the ANSYS element library. To obtain the buckling load, the arc-length method was used in the nonlinear analysis. Both material and geometric nonlinearities were activated during the analysis. The conclusion of this study is that short-radius and thin-walled toroidal shell produces higher buckling load.

Tensile testing grips ensure uniform loading of bimetal tubing specimens

NASA Technical Reports Server (NTRS)

Driscol, S. D.; Hunt, V.

1968-01-01

Tensile testing grip uniformly distributes stresses to the internal and external tube of bimetal tubing specimens. The grip is comprised of a slotted external tube grip, a slotted internal tube grip, a machine bolt and nut, an internal grip expansion cone, and an external grip compression nut.

Elastic-Plastic Nonlinear Response of a Space Shuttle External Tank Stringer. Part 2; Thermal and Mechanical Loadings

NASA Technical Reports Server (NTRS)

Knight, Norman F., Jr.; Warren, Jerry E.; Elliott, Kenny B.; Song, Kyongchan; Raju, Ivatury S.

2012-01-01

Elastic-plastic, large-deflection nonlinear thermo-mechanical stress analyses are performed for the Space Shuttle external tank s intertank stringers. Detailed threedimensional finite element models are developed and used to investigate the stringer s elastic-plastic response for different thermal and mechanical loading events from assembly through flight. Assembly strains caused by initial installation on an intertank panel are accounted for in the analyses. Thermal loading due to tanking was determined to be the bounding loading event. The cryogenic shrinkage caused by tanking resulted in a rotation of the intertank chord flange towards the center of the intertank, which in turn loaded the intertank stringer feet. The analyses suggest that the strain levels near the first three fasteners remain sufficiently high that a failure may occur. The analyses also confirmed that the installation of radius blocks on the stringer feet ends results in an increase in the stringer capability.

The effects of loaded and unloaded high-velocity resistance training on functional fitness among community-dwelling older adults.

PubMed

Glenn, Jordan M; Gray, Michelle; Binns, Ashley

2015-11-01

Physical function declines up to 4% per year after the age of 65. High-velocity training is important for maintaining muscular power and ultimately, physical function; however, whether performing high-velocity training without external resistance increases functional fitness among older adults remains unclear. The purpose of this investigation was to evaluate loaded and unloaded high-velocity training on lower body muscular power and functional fitness in older adults. Fifty-seven community-dwelling older adults (n = 16 males, n = 41 females) participated in this study. Inclusion criteria comprised ≥65 years of age, ≥24 on the Mini-mental state examination and no falls within past year. Two groups completed a 20-week high-velocity training intervention. The non-weighted group (UNLOAD, n = 27) performed the protocol without external load while the intervention group (LOAD, n = 30) used external loads via exercise machines. Functional fitness was assessed using the Short Physical Performance Battery (SPPB), Senior Fitness Test (SFT), hand-grip and lower body power measures. Multivariate ANOVA revealed that both groups had significant improvements for average (17.21%) and peak (9.26%) lower body power, along with the SFT arm curl (16.94%), chair stand (20.10%) and 8 ft. up-and-go (15.67%). Improvements were also noticed for SPPB 8 ft. walk (25.21%). However, improvements for all functional fitness measures were independent of training group. Unloaded high-velocity training increased functional fitness and power the same as loaded training. The ability of high-velocity movements to elicit gains in functional fitness without external loads may help health professionals develop fitness programs when time/space is limiting factor. © The Author 2015. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

The effect of external coaptation on plate deformation in an ex vivo model of canine pancarpal arthrodesis.

PubMed

Woods, S; Wallace, R J; Mosley, J R

2012-01-01

Since external coaptation is applied clinically to prevent plate failure during healing in canine pancarpal arthrodesis (PCA), we tested the hypothesis that external coaptation does not significantly reduce plate strain in an experimental ex vivo model of canine PCA. Ten thoracic limbs from healthy Greyhounds euthanatized for reasons un- related to the study were harvested and the carpus was stabilised with a dorsally applied 2.7/3.5 mm hybrid PCA plate. The strain in the plate adjacent to the most distal radial screw hole (R4) and the radial carpal bone (RCB) screw hole was measured as the limbs were loaded axially to a load that approximated that of controlled walking. Each limb was tested with and without external coaptation in place. Mean strain amplitude at the RCB was -177.2 με (± 20.78) without external coaptation. Following cast application, strain reduced significantly to -34.7 με (± 9.84) (p <0.002). Mean strain at R4 was -89.4 με (± 22.10) without external support and -66.9 με (± 10.74) following application of a cast. This reduction in recorded strain was not statistically significant. The application of a cast to the distal portion of the limb significantly reduced strain in the 2.7/3.5 mm hybrid PCA plate, but the magnitude of the measured strain was low, suggesting that fatigue damage is unlikely to accumulate as a result of this type of loading and that external coaptation may not be necessary to prevent fatigue failure of the plate.

Coherently Enhanced Wireless Power Transfer.

PubMed

Krasnok, Alex; Baranov, Denis G; Generalov, Andrey; Li, Sergey; Alù, Andrea

2018-04-06

Extraction of electromagnetic energy by an antenna from impinging external radiation is at the basis of wireless communications and wireless power transfer (WPT). The maximum of transferred energy is ensured when the antenna is conjugately matched, i.e., when it is resonant and it has an equal coupling with free space and its load. This condition, however, can be easily affected by changes in the environment, preventing optimal operation of a WPT system. Here, we introduce the concept of coherently enhanced WPT that allows us to bypass this difficulty and achieve dynamic control of power transfer. The approach relies on coherent excitation of the waveguide connected to the antenna load with a backward propagating signal of specific amplitude and phase. This signal creates a suitable interference pattern at the load resulting in a modification of the local wave impedance, which in turn enables conjugate matching and a largely increased amount of extracted energy. We develop a simple theoretical model describing this concept, demonstrate it with full-wave numerical simulations for the canonical example of a dipole antenna, and verify experimentally in both near-field and far-field regimes.

Coherently Enhanced Wireless Power Transfer

NASA Astrophysics Data System (ADS)

Krasnok, Alex; Baranov, Denis G.; Generalov, Andrey; Li, Sergey; Alù, Andrea

2018-04-01

Extraction of electromagnetic energy by an antenna from impinging external radiation is at the basis of wireless communications and wireless power transfer (WPT). The maximum of transferred energy is ensured when the antenna is conjugately matched, i.e., when it is resonant and it has an equal coupling with free space and its load. This condition, however, can be easily affected by changes in the environment, preventing optimal operation of a WPT system. Here, we introduce the concept of coherently enhanced WPT that allows us to bypass this difficulty and achieve dynamic control of power transfer. The approach relies on coherent excitation of the waveguide connected to the antenna load with a backward propagating signal of specific amplitude and phase. This signal creates a suitable interference pattern at the load resulting in a modification of the local wave impedance, which in turn enables conjugate matching and a largely increased amount of extracted energy. We develop a simple theoretical model describing this concept, demonstrate it with full-wave numerical simulations for the canonical example of a dipole antenna, and verify experimentally in both near-field and far-field regimes.

Quantitative Structure – Property Relationship Modeling of Remote Liposome Loading Of Drugs

PubMed Central

Cern, Ahuva; Golbraikh, Alexander; Sedykh, Aleck; Tropsha, Alexander; Barenholz, Yechezkel; Goldblum, Amiram

2012-01-01

Remote loading of liposomes by trans-membrane gradients is used to achieve therapeutically efficacious intra-liposome concentrations of drugs. We have developed Quantitative Structure Property Relationship (QSPR) models of remote liposome loading for a dataset including 60 drugs studied in 366 loading experiments internally or elsewhere. Both experimental conditions and computed chemical descriptors were employed as independent variables to predict the initial drug/lipid ratio (D/L) required to achieve high loading efficiency. Both binary (to distinguish high vs. low initial D/L) and continuous (to predict real D/L values) models were generated using advanced machine learning approaches and five-fold external validation. The external prediction accuracy for binary models was as high as 91–96%; for continuous models the mean coefficient R2 for regression between predicted versus observed values was 0.76–0.79. We conclude that QSPR models can be used to identify candidate drugs expected to have high remote loading capacity while simultaneously optimizing the design of formulation experiments. PMID:22154932

Effect of deltoid tension and humeral version in reverse total shoulder arthroplasty: a biomechanical study.

PubMed

Henninger, Heath B; Barg, Alexej; Anderson, Andrew E; Bachus, Kent N; Tashjian, Robert Z; Burks, Robert T

2012-04-01

No clear recommendations exist regarding optimal humeral component version and deltoid tension in reverse total shoulder arthroplasty (TSA). A biomechanical shoulder simulator tested humeral versions (0°, 10°, 20° retroversion) and implant thicknesses (-3, 0, +3 mm from baseline) after reverse TSA in human cadavers. Abduction and external rotation ranges of motion as well as abduction and dislocation forces were quantified for native arms and arms implanted with 9 combinations of humeral version and implant thickness. Resting abduction angles increased significantly (up to 30°) after reverse TSA compared with native shoulders. With constant posterior cuff loads, native arms externally rotated 20°, whereas no external rotation occurred in implanted arms (20° net internal rotation). Humeral version did not affect rotational range of motion but did alter resting abduction. Abduction forces decreased 30% vs native shoulders but did not change when version or implant thickness was altered. Humeral center of rotation was shifted 17 mm medially and 12 mm inferiorly after implantation. The force required for lateral dislocation was 60% less than anterior and was not affected by implant thickness or version. Reverse TSA reduced abduction forces compared with native shoulders and resulted in limited external rotation and abduction ranges of motion. Because abduction force was reduced for all implants, the choice of humeral version and implant thickness should focus on range of motion. Lateral dislocation forces were less than anterior forces; thus, levering and inferior/posterior impingement may be a more probable basis for dislocation (laterally) than anteriorly directed forces. Copyright © 2012 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Mosby, Inc. All rights reserved.

Internal and External Match Loads of University-Level Soccer Players: A Comparison Between Methods.

PubMed

Sparks, Martinique; Coetzee, Ben; Gabbett, Tim J

2017-04-01

Sparks, M, Coetzee, B, and Gabbett, TJ. Internal and external match loads of university-level soccer players: a comparison between methods. J Strength Cond Res 31(4): 1072-7077, 2017-The aim of this study was to use individualized intensity zones to compare the external (velocity and player load, PL) and internal loads (heart rate, HR) of a cohort of university-level soccer players. Thirteen soccer players completed a 40-m maximum speed test and the Yo-Yo intermittent recovery test 1 (Yo-Yo IR1) to determine individualized velocity and HR thresholds. Heart rate values and global positioning system (GPS) data of each player were recorded during 5 league matches. A large (r = 0.46; p ≤ 0.01) correlation was found between time spent in the low-intensity (LI) velocity zone (LIVZ) and the LI HR zone. Similarly, there were moderate (r = 0.25; p ≤ 0.01) to large (r = 0.57; p ≤ 0.01) correlations between the relative and absolute time spent in the moderate-intensity (MI) velocity zone (MIVZ) and the MI HR zone. No significant correlations (p ≤ 0.01) existed between the high-intensity (HI) velocity zones (HIVZ) and the HI HR zone. On the other hand, PL showed significant correlations with all velocity and HR (absolute and relative) variables, with the exception of a nonsignificant correlation between the HI HR variables and PL. To conclude, PL showed good correlations with both velocity and HR zones and therefore may have the potential to serve as a good indicator of both external and internal soccer match loads.

A loose bolt delays loading of Endeavour's external tank

NASA Technical Reports Server (NTRS)

2000-01-01

This view shows the pipe (center top) leading toward Endeavour from the side of the White Room at Launch Pad 39B. A loose bracket observed hanging down from the pipe delayed loading of Endeavour's external tank by several hours to allow technicians to remove it. A 'U' bolt connects the bracket to a fire suppression water line attached to the exterior of the White Room. The loose bolt could have possibly created a debris hazard.

Force reduction induced by unidirectional transversal muscle loading is independent of local pressure.

PubMed

Siebert, Tobias; Rode, Christian; Till, Olaf; Stutzig, Norman; Blickhan, Reinhard

2016-05-03

Transversal unidirectional compression applied to muscles via external loading affects muscle contraction dynamics in the longitudinal direction. A recent study reported decreasing longitudinal muscle forces with increasing transversal load applied with a constant contact area (i.e., leading to a simultaneous increase in local pressure). To shed light on these results, we examine whether the decrease in longitudinal force depends on the load, the local pressure, or both. To this end, we perform isometric experiments on rat M. gastrocnemius medialis without and with transversal loading (i) changing the local pressure from 1.1-3.2Ncm(-2) (n=9) at a constant transversal load (1.62N) and (ii) increasing the transversal load (1.15-3.45N) at a constant local pressure of 2.3Ncm(-2) (n=7). While we did not note changes in the decrease in longitudinal muscle force in the first experiment, the second experiment resulted in an almost-linear reduction of longitudinal force between 7.5±0.6% and 14.1±1.7%. We conclude that the observed longitudinal force reduction is not induced by local effects such as malfunction of single muscle compartments, but that similar internal stress conditions and myofilament configurations occur when the local pressure changes given a constant load. The decreased longitudinal force may be explained by increased internal pressure and a deformed myofilament lattice that is likely associated with the decomposition of cross-bridge forces on the one hand and the inhibition of cross-bridges on the other hand. Copyright © 2016 Elsevier Ltd. All rights reserved.

The Financial Sector and Sustainable Development

NASA Astrophysics Data System (ADS)

Rusko, Miroslav; Korauš, Anton

2010-01-01

Growing load and deterioration of the environment can be interpreted as a result of some external effects interventions. While the positive externalities influence the positive productional and utilizational functions of other subjects, the negative externalities influence the negative ones. Both types of external effects can act as parcial or global externalities. Linking the environmental issues to economy and finance is an important sphere. Coimplementation of both marketing and environmental audits is an important element of this sphere too.

14 CFR 133.47 - Rotorcraft-load combination flight manual.

Code of Federal Regulations, 2010 CFR

2010-01-01

.... 133.47 Section 133.47 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... ROTORCRAFT EXTERNAL-LOAD OPERATIONS Airworthiness Requirements § 133.47 Rotorcraft-load combination flight... been demonstrated in accordance with §§ 133.41 and 133.43; and (c) In the information section of the...

Biomechanical comparison of supraacetabular external fixation and anterior pelvic bridge plating.

PubMed

Çavuşoğlu, Ali Turgay; Erbay, Fatma Kübra; Özsoy, Mehmet Hakan; Demir, Teyfik

2017-10-01

Unstable pelvic ring injuries are complex and risky injuries due to high morbidity and mortality. Although anterior pelvic external fixator is a suitable method for rapid stabilization of an injured pelvic ring, due to some disadvantages such as high complication rate, nerve damage, and difficulties of patient's mobility and comfort, there has recently been increased searching for alternative methods for stabilization of the pelvic ring. Pubic symphysis zone freely moves in pelvic models. This study aims to evaluate the biomechanical stability of anterior pelvic bridge plating and compare it with supraacetabular external fixators in an untreated unstable pelvic fracture model. Samples were loaded statically with 2-mm/min loading rate in single leg standing position. Maximum load was 2.3 kN. When loading the samples, photographs were taken continuously. Stiffness values were calculated from the load displacement curves. Some reference parameters were described and were measured from unloaded and 2.3-kN-loaded photographs of the test. The mean stiffness values were 491.14 ± 52.22, 478.55 ± 41.44, and 470.25 ± 44.51 N/mm for anterior pelvic bridge plating group, supraacetabular external fixator group, and Control group, respectively. According to the measured parameters from photographs, the mean displacement at the pubic symphysis was 4.7 ± 0.32, 15.8 ± 2.01, and 18.2 ± 0.47 mm for anterior pelvic bridge plating, supraacetabular external fixator, and Control group, respectively. The highest displacement in the pubic symphysis was found in Control group, and minimum displacement was observed in anterior pelvic bridge plating group. When the perpendicular distance between the right and left lower end of ischium was examined, it was observed that displacement was minimum in anterior pelvic bridge plating group compared to other two groups, regarding to the high stability of pubic symphysis. In conclusion, this study revealed superiority of anterior subcutaneous plate fixation with biomechanical results.

Effect of Loading History on Airway Smooth Muscle Cell-Matrix Adhesions.

PubMed

Irons, Linda; Owen, Markus R; O'Dea, Reuben D; Brook, Bindi S

2018-06-05

Integrin-mediated adhesions between airway smooth muscle (ASM) cells and the extracellular matrix (ECM) regulate how contractile forces generated within the cell are transmitted to its external environment. Environmental cues are known to influence the formation, size, and survival of cell-matrix adhesions, but it is not yet known how they are affected by dynamic fluctuations associated with tidal breathing in the intact airway. Here, we develop two closely related theoretical models to study adhesion dynamics in response to oscillatory loading of the ECM, representing the dynamic environment of ASM cells in vivo. Using a discrete stochastic-elastic model, we simulate individual integrin binding and rupture events and observe two stable regimes in which either bond formation or bond rupture dominate, depending on the amplitude of the oscillatory loading. These regimes have either a high or low fraction of persistent adhesions, which could affect the level of strain transmission between contracted ASM cells and the airway tissue. For intermediate loading, we observe a region of bistability and hysteresis due to shared loading between existing bonds; the level of adhesion depends on the loading history. These findings are replicated in a related continuum model, which we use to investigate the effect of perturbations mimicking deep inspirations (DIs). Because of the bistability, a DI applied to the high adhesion state could either induce a permanent switch to a lower adhesion state or allow a return of the system to the high adhesion state. Transitions between states are further influenced by the frequency of oscillations, cytoskeletal or ECM stiffnesses, and binding affinities, which modify the magnitudes of the stable adhesion states as well as the region of bistability. These findings could explain (in part) the transient bronchodilatory effect of a DI observed in asthmatics compared to a more sustained effect in normal subjects. Copyright © 2018 Biophysical Society. Published by Elsevier Inc. All rights reserved.

Effect of cyclic load on vertical misfit of prefabricated and cast implant single abutment

PubMed Central

DE JESUS TAVAREZ, Rudys Rodolfo; BONACHELA, Wellington Cardoso; XIBLE, Anuar Antônio

2011-01-01

Objective The purpose of this in vitro study was to evaluate misfit alterations at the implant/abutment interface of external and internal connection implant systems when subjected to cyclic loading. Material and Methods Standard metal crowns were fabricated for 5 groups (n=10) of implant/abutment assemblies: Group 1, external hexagon implant and UCLA cast-on premachined abutment; Group 2, internal hexagon implant and premachined abutment; Group 3, internal octagon implant and prefabricated abutment; Group 4, external hexagon implant and UCLA cast-on premachined abutment; and Group 5, external hexagon implant and Ceraone abutment. For groups 1, 2, 3 and 5, the crowns were cemented on the abutments and in group 4 crowns were screwed directly on the implant. The specimens were subjected to 500,000 cycles at 19.1 Hz of frequency and non-axial load of 133 N in a MTS 810 machine. The vertical misfit (μm) at the implant/abutment interface was evaluated before (B) and after (A) application of the cyclic loading. Data were analyzed statistically by using two-away ANOVA and Tukey’s post-hoc test (p<0.05). Results Before loading values showed no difference among groups 2 (4.33±3.13), 3 (4.79±3.43) and 5 (3.86±4.60); between groups 1 (12.88±6.43) and 4 (9.67±3.08), and among groups 2, 3 and 4. However, groups 1 and 4 were significantly different from groups 2, 3 and 5. After loading values of groups 1 (17.28±8.77) and 4 (17.78±10.99) were significantly different from those of groups 2 (4.83±4.50), 3 (8.07±4.31) and 5 (3.81±4.84). There was a significant increase in misfit values of groups 1, 3 and 4 after cyclic loading, but not for groups 2 and 5. Conclusion The cyclic loading and type of implant/abutment connection may develop a role on the vertical misfit at the implant/abutment interface. PMID:21437464

Importance of tibial slope for stability of the posterior cruciate ligament deficient knee.

PubMed

Giffin, J Robert; Stabile, Kathryne J; Zantop, Thore; Vogrin, Tracy M; Woo, Savio L-Y; Harner, Christopher D

2007-09-01

Previous studies have shown that increasing tibial slope can shift the resting position of the tibia anteriorly. As a result, sagittal osteotomies that alter slope have recently been proposed for treatment of posterior cruciate ligament (PCL) injuries. Increasing tibial slope with an osteotomy shifts the resting position anteriorly in a PCL-deficient knee, thereby partially reducing the posterior tibial "sag" associated with PCL injury. This shift in resting position from the increased slope causes a decrease in posterior tibial translation compared with the PCL-deficient knee in response to posterior tibial and axial compressive loads. Controlled laboratory study. Three knee conditions were tested with a robotic universal force-moment sensor testing system: intact, PCL-deficient, and PCL-deficient with increased tibial slope. Tibial slope was increased via a 5-mm anterior opening wedge osteotomy. Three external loading conditions were applied to each knee condition at 0 degrees, 30 degrees, 60 degrees, 90 degrees, and 120 degrees of knee flexion: (1) 134-N anterior-posterior (A-P) tibial load, (2) 200-N axial compressive load, and (3) combined 134-N A-P and 200-N axial loads. For each loading condition, kinematics of the intact knee were recorded for the remaining 5 degrees of freedom (ie, A-P, medial-lateral, and proximal-distal translations, internal-external and varus-valgus rotations). Posterior cruciate ligament deficiency resulted in a posterior shift of the tibial resting position to 8.4 +/- 2.6 mm at 90 degrees compared with the intact knee. After osteotomy, tibial slope increased from 9.2 degrees +/- 1.0 degrees in the intact knee to 13.8 degrees +/- 0.9 degrees. This increase in slope reduced the posterior sag of the PCL-deficient knee, shifting the resting position anteriorly to 4.0 +/- 2.0 mm at 90 degrees. Under a 200-N axial compressive load with the osteotomy, an additional increase in anterior tibial translation to 2.7 +/- 1.7 mm at 30 degrees was observed. Under a 134-N A-P load, the osteotomy did not significantly affect total A-P translation when compared with the PCL-deficient knee. However, because of the anterior shift in resting position, there was a relative decrease in posterior tibial translation and increase in anterior tibial translation. Increasing tibial slope in a PCL-deficient knee reduces tibial sag by shifting the resting position of the tibia anteriorly. This sag is even further reduced when the knee is subjected to axial compressive loads. These data suggest that increasing tibial slope may be beneficial for patients with PCL-deficient knees.

Non-driving intersegmental knee moments in cycling computed using a model that includes three-dimensional kinematics of the shank/foot and the effect of simplifying assumptions.

PubMed

Gregersen, Colin S; Hull, M L

2003-06-01

Assessing the importance of non-driving intersegmental knee moments (i.e. varus/valgus and internal/external axial moments) on over-use knee injuries in cycling requires the use of a three-dimensional (3-D) model to compute these loads. The objectives of this study were: (1) to develop a complete, 3-D model of the lower limb to calculate the 3-D knee loads during pedaling for a sample of the competitive cycling population, and (2) to examine the effects of simplifying assumptions on the calculations of the non-driving knee moments. The non-driving knee moments were computed using a complete 3-D model that allowed three rotational degrees of freedom at the knee joint, included the 3-D inertial loads of the shank/foot, and computed knee loads in a shank-fixed coordinate system. All input data, which included the 3-D segment kinematics and the six pedal load components, were collected from the right limb of 15 competitive cyclists while pedaling at 225 W and 90 rpm. On average, the peak varus and internal axial moments of 7.8 and 1.5 N m respectively occurred during the power stroke whereas the peak valgus and external axial moments of 8.1 and 2.5 N m respectively occurred during the recovery stroke. However, the non-driving knee moments were highly variable between subjects; the coefficients of variability in the peak values ranged from 38.7% to 72.6%. When it was assumed that the inertial loads of the shank/foot for motion out of the sagittal plane were zero, the root-mean-squared difference (RMSD) in the non-driving knee moments relative to those for the complete model was 12% of the peak varus/valgus moment and 25% of the peak axial moment. When it was also assumed that the knee joint was revolute with the flexion/extension axis perpendicular to the sagittal plane, the RMSD increased to 24% of the peak varus/valgus moment and 204% of the peak axial moment. Thus, the 3-D orientation of the shank segment has a major affect on the computation of the non-driving knee moments, while the inertial contributions to these loads for motions out of the sagittal plane are less important.

Learning STEM through Integrative Visual Representations

ERIC Educational Resources Information Center

Virk, Satyugjit Singh

2013-01-01

Previous cognitive models of memory have not comprehensively taken into account the internal cognitive load of chunking isolated information and have emphasized the external cognitive load of visual presentation only. Under the Virk Long Term Working Memory Multimedia Model of cognitive load, drawing from the Cowan model, students presented with…

14 CFR 25.365 - Pressurized compartment loads.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Pressurized compartment loads. For airplanes with one or more pressurized compartments the following apply: (a... differential loads from zero up to the maximum relief valve setting. (b) The external pressure distribution in... zero up to the maximum allowed during landing. (d) The airplane structure must be designed to be able...

The Pandolf equation under-predicts the metabolic rate of contemporary military load carriage.

PubMed

Drain, Jace R; Aisbett, Brad; Lewis, Michael; Billing, Daniel C

2017-11-01

This investigation assessed the accuracy of error of the Pandolf load carriage energy expenditure equation when simulating contemporary military conditions (load distribution, external load and walking speed). Within-participant design. Sixteen male participants completed 10 trials comprised of five walking speeds (2.5, 3.5, 4.5, 5.5 and 6.5km·h -1 ) and two external loads (22.7 and 38.4kg). The Pandolf equation demonstrated poor predictive precision, with a mean bias of 124.9W and -48.7 to 298.5W 95% limits of agreement. Furthermore, the Pandolf equation systematically under-predicted metabolic rate (p<0.05) across the 10 speed-load combinations. Predicted metabolic rate error ranged from 12-33% across all conditions with the 'moderate' walking speeds (i.e. 4.5-5.5km·h -1 ) yielding less prediction error (12-17%) when compared to the slower and faster walking speeds (21-33%). Factors such as mechanical efficiency and load distribution contribute to the impaired predictive accuracy. The authors suggest the Pandolf equation should be applied to military load carriage with caution. Copyright © 2017 Sports Medicine Australia. All rights reserved.

Handbook of structural stability part VI : strength of stiffened curved plates and shells

NASA Technical Reports Server (NTRS)

Becker, Herbert

1958-01-01

A comprehensive review of failure of stiffened curved plates and shells is presented. Panel instability in stiffened curved plates and general instability of stiffened cylinders are discussed. The loadings considered for the plates are axial, shear, and the combination of the two. For the cylinders, bending, external pressure, torsion, transverse shear, and combinations of these loads are considered. When possible, test data and theory were correlated. General instability in stiffened cylinders was investigated. For bending and torsion loads, test data and theory were correlated. For external pressure several existing theories were compared. As a result of this investigation a unified theoretical approach to analysis of general instability in stiffened cylinders was developed. (author)

Noise effects on the health status in a dynamic failure model for living organisms

NASA Astrophysics Data System (ADS)

Kang, H.; Jo, J.; Choi, M. Y.; Choi, J.; Yoon, B.-G.

2007-03-01

We study internal and external noise effects on the healthy-unhealthy transition and related phenomena in a dynamic failure model for living organisms. It is found that internal noise makes the system weaker, leading to breakdown under smaller stress. The discontinuous healthy-unhealthy transition in a system with global load sharing below a critical point is naturally explained in terms of the bistability for the health status. External noise present in constant stress gives similar results; further, it induces resonance in response to periodic stress, regardless of load transfer. In the case of local load sharing, such periodic stress is revealed more hazardous than the constant stress.

Load-dependent surface diffusion model for analyzing the kinetics of protein adsorption onto mesoporous materials.

PubMed

Marbán, Gregorio; Ramírez-Montoya, Luis A; García, Héctor; Menéndez, J Ángel; Arenillas, Ana; Montes-Morán, Miguel A

2018-02-01

The adsorption of cytochrome c in water onto organic and carbon xerogels with narrow pore size distributions has been studied by carrying out transient and equilibrium batch adsorption experiments. It was found that equilibrium adsorption exhibits a quasi-Langmuirian behavior (a g coefficient in the Redlich-Peterson isotherms of over 0.95) involving the formation of a monolayer of cyt c with a depth of ∼4nm on the surface of all xerogels for a packing density of the protein inside the pores of 0.29gcm -3 . A load-dependent surface diffusion model (LDSDM) has been developed and numerically solved to fit the experimental kinetic adsorption curves. The results of the LDSDM show better fittings than the standard homogeneous surface diffusion model. The value of the external mass transfer coefficient obtained by numerical optimization confirms that the process is controlled by the intraparticle surface diffusion of cyt c. The surface diffusion coefficients decrease with increasing protein load down to zero for the maximum possible load. The decrease is steeper in the case of the xerogels with the smallest average pore diameter (∼15nm), the limit at which the zero-load diffusion coefficient of cyt c also begins to be negatively affected by interactions with the opposite wall of the pore. Copyright © 2017 Elsevier Inc. All rights reserved.

FBI fingerprint identification automation study: AIDS 3 evaluation report. Volume 6: Environmental analysis

NASA Technical Reports Server (NTRS)

Mulhall, B. D. L.

1980-01-01

The results of the analysis of the external environment of the FBI Fingerprint Identification Division are presented. Possible trends in the future environment of the Division that may have an effect on the work load were projected to determine if future work load will lie within the capability range of the proposed new system, AIDS 3. Two working models of the environment were developed, the internal and external model, and from these scenarios the projection of possible future work load volume and mixture was developed. Possible drivers of work load change were identified and assessed for upper and lower bounds of effects. Data used for the study were derived from historical information, analysis of the current situation and from interviews with various agencies who are users of or stakeholders in the present system.

Behavior of medial gastrocnemius motor units during postural reactions to external perturbations after stroke.

PubMed

Pollock, C L; Ivanova, T D; Hunt, M A; Garland, S J

2015-10-01

This study investigated the behavior of medial gastrocnemius (GM) motor units (MU) during external perturbations in standing in people with chronic stroke. GM MUs were recorded in standing while anteriorly-directed perturbations were introduced by applying loads of 1% body mass (BM) at the pelvis every 25-40s until 5% BM was maintained. Joint kinematics, surface electromyography (EMG), and force platform measurements were assessed. Although external loads caused a forward progression of the anterior-posterior centre of pressure (APCOP), people with stroke decreased APCOP velocity and centre of mass (COM) velocity immediately following the highest perturbations, thereby limiting movement velocity in response to perturbations. MU firing rate did not increase with loading but the GM EMG magnitude increased, reflecting MU recruitment. MU inter spike interval (ISI) during the dynamic response was negatively correlated with COM velocity and hip angular velocity. The GM utilized primarily MU recruitment to maintain standing during external perturbations. The lack of MU firing rate modulation occurred with a change in postural central set. However, the relationship of MU firing rate with kinematic variables suggests underlying long-loop responses may be somewhat intact after stroke. People with stroke demonstrate alterations in postural control strategies which may explain MU behavior with external perturbations. Copyright © 2014 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

EFFECT OF AXIAL TIBIAL TORQUE DIRECTION ON ACL RELATIVE STRAIN AND STRAIN RATE IN AN IN VITRO SIMULATED PIVOT LANDING

PubMed Central

Oh, Youkeun K.; Kreinbrink, Jennifer L.; Wojtys, Edward M.; Ashton-Miller, James A.

2011-01-01

Anterior cruciate ligament (ACL) injuries most frequently occur under the large loads associated with a unipedal jump landing involving a cutting or pivoting maneuver. We tested the hypotheses that internal tibial torque would increase the anteromedial (AM) bundle ACL relative strain and strain rate more than would the corresponding external tibial torque under the large impulsive loads associated with such landing maneuvers. Twelve cadaveric female knees [mean (SD) age: 65.0 (10.5) years] were tested. Pretensioned quadriceps, hamstring and gastrocnemius muscle-tendon unit forces maintained an initial knee flexion angle of 15°. A compound impulsive test load (compression, flexion moment and internal or external tibial torque) was applied to the distal tibia while recording the 3-D knee loads and tibofemoral kinematics. AM-ACL relative strain was measured using a 3mm DVRT. In this repeated measures experiment, the Wilcoxon Signed-Rank test was used to test the null hypotheses with p<0.05 considered significant. The mean (± SD) peak AM-ACL relative strains were 5.4±3.7 % and 3.1±2.8 % under internal and external tibial torque, respectively. The corresponding mean (± SD) peak AM-ACL strain rates reached 254.4±160.1 %/sec and 179.4±109.9 %/sec, respectively. The hypotheses were supported in that the normalized mean peak AM-ACL relative strain and strain rate were 70% and 42% greater under internal than external tibial torque, respectively (p=0.023, p=0.041). We conclude that internal tibial torque is a potent stressor of the ACL because it induces a considerably (70%) larger peak strain in the AM-ACL than does a corresponding external tibial torque. PMID:22025178

External And Internal Work Of A T-6 Paraplegic Propelling A Wheelchair And Arm Cranking A Cycle Ergometer: Case Study

NASA Astrophysics Data System (ADS)

Novak, Charles W.

1982-02-01

In this, the International Year of the Disabled, attention is directed among other areas toward rehabilitation and sports participation of wheelchair users. As an application of movement analysis in medicine and rehabilitation and as an application of sports research using biomechanics, this investigation was performed to compare the results of two methods of gathering data on the stress of wheelchair propelling at equivalent work loads and to account for differences in physiological responses with a mechanical analysis of wheelchair propelling. Physiological data collected were heart rate, systolic blood pressure, and rate-pressure product. A biomechanical cinematography analysis was used to determine external work in wheelchair propelling and to determine the extent to which modifications in segment actionsoccurred during increasing magnitude of work. A cycle ergometer was adjusted to replicate external work loads performed during wheelchair propelling. A t-test of equivalent external work loads indicated that heart rate was not different between the two exercise modes at the .05 level of significance. The t-test did indicate a significant difference in systolic blood pressure and rate-pressure product at the .05 level of significance. The biomechanical analysis of wheelchair propelling established that an increase in external work was accomplished by a decrease in the range of motion and an increase in the speed of movement. During cycle ergometry the range and speed of movement remained the same while resistance was increased. Results of the study established that while heart rate for equivalent external work loads was the same for wheelchair propelling and arm cranking cycle ergometry, systolic blood pressure and rate-pressure product were not the same. The suggestion was that some means of propelling a wheelchair other than that which is con-sidered "standard" might be considered which produces less stressful responses in wheelchair users.

Doxorubicin-Loaded Nanobubbles Combined with Extracorporeal Shock Waves: Basis for a New Drug Delivery Tool in Anaplastic Thyroid Cancer.

PubMed

Marano, Francesca; Argenziano, Monica; Frairia, Roberto; Adamini, Aloe; Bosco, Ornella; Rinella, Letizia; Fortunati, Nicoletta; Cavalli, Roberta; Catalano, Maria Graziella

2016-05-01

No standard chemotherapy is available for anaplastic thyroid cancer (ATC). Drug-loaded nanobubbles (NBs) are a promising innovative anticancer drug formulation, and combining them with an externally applied trigger may further control drug release at the target region. Extracorporeal shock waves (ESWs) are acoustic waves widely used in urology and orthopedics, with no side effects. The aim of the present work was to combine ESWs and new doxorubicin-loaded glycol chitosan NBs in order to target doxorubicin and enhance its antitumor effect in ATC cell lines. CAL-62 and 8305C cells were treated with empty NBs, fluorescent NBs, free doxorubicin, and doxorubicin-loaded NBs in the presence or in the absence of ESWs. NB entrance was evaluated by fluorescence microscopy and flow cytofluorimetry. Cell viability was assessed by Trypan Blue exclusion and WST-1 proliferation assays. Doxorubicin intracellular content was measured by high-performance liquid chromatography. Treatment with empty NBs and ESWs, even in combination, was safe, as cell viability and growth were not affected. Loading NBs with doxorubicin and combining them with ESWs generated the highest cytotoxic effect, resulting in drug GI50 reduction of about 40%. Mechanistically, ESWs triggered intracellular drug release from NBs, resulting in the highest nuclear drug content. Combined treatment with doxorubicin-loaded NBs and ESWs is a promising drug delivery tool for ATC treatment with the possibility of using lower doxorubicin doses and thus limiting its systemic side effects.

Using "Mighty Mouse" to understand masticatory plasticity: myostatin-deficient mice and musculoskeletal function.

PubMed

Ravosa, Matthew J; López, Elisabeth K; Menegaz, Rachel A; Stock, Stuart R; Stack, M Sharon; Hamrick, Mark W

2008-09-01

Knockout mice lacking myostatin (Mstn), a negative regulator of the growth of skeletal muscle, develop significant increases in the relative mass of masticatory muscles as well as the ability to generate higher maximal muscle forces. Wild-type and Mstn-deficient mice were compared to investigate the postnatal influence of elevated masticatory loads due to increased jaw-adductor and bite forces on the biomineralization of mandibular articular and cortical bone, the internal structure of the jaw joints, and the composition of temporomandibular joint (TMJ) articular cartilage. To provide an interspecific perspective on the long-term responses of mammalian jaw joints to altered loading conditions, the findings on mice were compared to similar data for growing rabbits subjected to long-term dietary manipulation. Statistically significant differences in joint proportions and bone mineral density between normal and Mstn-deficient mice, which are similar to those observed between rabbit loading cohorts, underscore the need for a comprehensive analysis of masticatory tissue plasticity vis-à-vis altered mechanical loads, one in which variation in external and internal structure are considered. Differences in the expression of proteoglycans and type-II collagen in TMJ articular cartilage between the mouse and rabbit comparisons suggest that the duration and magnitude of the loading stimulus will significantly affect patterns of adaptive and degradative responses. These data on mammals subjected to long-term loading conditions offer novel insights regarding variation in ontogeny, life history, and the ecomorphology of the feeding apparatus.

A theoretical analysis and finite element simulation of fixator-bone system stiffness on healing progression.

PubMed

Li, Jianfeng; Zhao, Xia; Hu, Xiaojie; Tao, Chunjing; Ji, Run

2018-03-01

The unilateral external fixator has become a quick and easy application for fracture stabilization of the extremities; the main value for evaluation of mechanical stability of the external fixator is stiffness. The stiffness property of the external fixator affects the local biomechanical environment of fractured bone. In this study, a theoretical model with changing Young's modulus of the callus is established by using the Castigliano's theory, investigating compression stiffness, torsional stiffness and bending stiffness of the fixator-bone system during the healing process. The effects of pin deviation angle on three stiffness methods are also investigated. In addition, finite element simulation is discussed regarding the stress distribution between the fixator and bone. The results reveal the three stiffness evaluation methods are similar for the fixator-bone system. Finite element simulation shows that with increased healing time, the transmission of the load between the fixator and bone are different. In addition, the finite element analyses verify the conclusions obtained from the theoretical model. This work helps orthopedic doctors to monitor the progression of fracture healing and determine the appropriate time for removal of a fixation device and provide important theoretical methodology.

Full-scale testing of leakage of blast waves inside a partially vented room exposed to external air blast loading

NASA Astrophysics Data System (ADS)

Codina, R.; Ambrosini, D.

2018-03-01

For the last few decades, the effects of blast loading on structures have been studied by many researchers around the world. Explosions can be caused by events such as industrial accidents, military conflicts or terrorist attacks. Urban centers have been prone to various threats including car bombs, suicide attacks, and improvised explosive devices. Partially vented constructions subjected to external blast loading represent an important topic in protective engineering. The assessment of blast survivability inside structures and the development of design provisions with respect to internal elements require the study of the propagation and leakage of blast waves inside buildings. In this paper, full-scale tests are performed to study the effects of the leakage of blast waves inside a partially vented room that is subjected to different external blast loadings. The results obtained may be useful for proving the validity of different methods of calculation, both empirical and numerical. Moreover, the experimental results are compared with those computed using the empirical curves of the US Defense report/manual UFC 3-340. Finally, results of the dynamic response of the front masonry wall are presented in terms of accelerations and an iso-damage diagram.

[Analysis of the results of the SEIMC External Quality Control Program. Year 2013].

PubMed

de Gopegui Bordes, Enrique Ruiz; Orta Mira, Nieves; Del Remedio Guna Serrano, M; Medina González, Rafael; Rosario Ovies, María; Poveda, Marta; Gimeno Cardona, Concepción

2015-07-01

The External Quality Control Program of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) include controls for bacteriology, serology, mycology, parasitology, mycobacteria, virology, molecular microbiology and HIV-1, HCV and HBV viral loads. This manuscript presents the analysis of results obtained of the participants from the 2013 SEIMC External Quality Control Programme, except viral loads controls, that they are summarized in a manuscript abroad. As a whole, the results obtained in 2013 confirm the excellent skill and good technical standards found in previous editions. However, erroneous results can be obtained in any laboratory and in clinically relevant determinations. Once again, the results of this program highlighted the need to implement both internal and external controls in order to assure the maximal quality of the microbiological tests. Copyright © 2015 Elsevier España, S.L.U. All rights reserved.

Load Carriage Capacity of the Dismounted Combatant - A Commanders’ Guide

DTIC Science & Technology

2012-10-01

predictive model has been used throughout this document to predict the physiological burden (i.e. energy cost ) of representative load carriage...scenarios. As a general guide this model indicates that a 10 kg increase in external load is metabolically equivalent (i.e. energy cost ) to an increase...larger increases in energy cost for a load carriage task. The multi-factorial nature of human load carriage capacity makes it difficult to set

Advanced gearbox technology

NASA Technical Reports Server (NTRS)

Anderson, N. E.; Cedoz, R. W.; Salama, E. E.; Wagner, D. A.

1987-01-01

An advanced 13,000 HP, counterrotating (CR) gearbox was designed and successfully tested to provide a technology base for future designs of geared propfan propulsion systems for both commercial and military aircraft. The advanced technology CR gearbox was designed for high efficiency, low weight, long life, and improved maintainability. The differential planetary CR gearbox features double helical gears, double row cylindrical roller bearings integral with planet gears, tapered roller prop support bearings, and a flexible ring gear and diaphragm to provide load sharing. A new Allison propfan back-to-back gearbox test facility was constructed. Extensive rotating and stationary instrumentation was used to measure temperature, strain, vibration, deflection and efficiency under representative flight operating conditions. The tests verified smooth, efficient gearbox operation. The highly-instrumented advanced CR gearbox was successfully tested to design speed and power (13,000 HP), and to a 115 percent overspeed condition. Measured CR gearbox efficiency was 99.3 percent at the design point based on heat loss to the oil. Tests demonstrated low vibration characteristics of double helical gearing, proper gear tooth load sharing, low stress levels, and the high load capacity of the prop tapered roller bearings. Applied external prop loads did not significantly affect gearbox temperature, vibration, or stress levels. Gearbox hardware was in excellent condition after the tests with no indication of distress.

A sediment resuspension and water quality model of Lake Okeechobee

USGS Publications Warehouse

James, R.T.; Martin, J.; Wool, T.; Wang, P.-F.

1997-01-01

The influence of sediment resuspension on the water quality of shallow lakes is well documented. However, a search of the literature reveals no deterministic mass-balance eutrophication models that explicitly include resuspension. We modified the Lake Okeeehobee water quality model - which uses the Water Analysis Simulation Package (WASP) to simulate algal dynamics and phosphorus, nitrogen, and oxygen cycles - to include inorganic suspended solids and algorithms that: (1) define changes in depth with changes in volume; (2) compute sediment resuspension based on bottom shear stress; (3) compute partition coefficients for ammonia and ortho-phosphorus to solids; and (4) relate light attenuation to solids concentrations. The model calibration and validation were successful with the exception of dissolved inorganic nitrogen species which did not correspond well to observed data in the validation phase. This could be attributed to an inaccurate formulation of algal nitrogen preference and/or the absence of nitrogen fixation in the model. The model correctly predicted that the lake is lightlimited from resuspended solids, and algae are primarily nitrogen limited. The model simulation suggested that biological fluxes greatly exceed external loads of dissolved nutrients; and sedimentwater interactions of organic nitrogen and phosphorus far exceed external loads. A sensitivity analysis demonstrated that parameters affecting resuspension, settling, sediment nutrient and solids concentrations, mineralization, algal productivity, and algal stoichiometry are factors requiring further study to improve our understanding of the Lake Okeechobee ecosystem.

Self-Sensing of Position-Related Loads in Continuous Carbon Fibers-Embedded 3D-Printed Polymer Structures Using Electrical Resistance Measurement

PubMed Central

Luan, Congcong; Shen, Hongyao; Fu, Jianzhong

2018-01-01

Condition monitoring in polymer composites and structures based on continuous carbon fibers show overwhelming advantages over other potentially competitive sensing technologies in long-gauge measurements due to their great electromechanical behavior and excellent reinforcement property. Although carbon fibers have been developed as strain- or stress-sensing agents in composite structures through electrical resistance measurements, the electromechanical behavior under flexural loads in terms of different loading positions still lacks adequate research, which is the most common situation in practical applications. This study establishes the relationship between the fractional change in electrical resistance of carbon fibers and the external loads at different loading positions along the fibers’ longitudinal direction. An approach for real-time monitoring of flexural loads at different loading positions was presented simultaneously based on this relationship. The effectiveness and feasibility of the approach were verified by experiments on carbon fiber-embedded three-dimensional (3D) printed thermoplastic polymer beam. The error in using the provided approach to monitor the external loads at different loading positions was less than 1.28%. The study fully taps the potential of continuous carbon fibers as long-gauge sensory agents and reinforcement in the 3D-printed polymer structures. PMID:29584665

The Quest for Comparability: Studying the Invariance of the Teachers’ Sense of Self-Efficacy (TSES) Measure across Countries

PubMed Central

Scherer, Ronny; Jansen, Malte; Nilsen, Trude; Areepattamannil, Shaljan; Marsh, Herbert W.

2016-01-01

Teachers’ self-efficacy is an important motivational construct that is positively related to a variety of outcomes for both the teachers and their students. This study addresses challenges associated with the commonly used ‘Teachers’ Sense of Self-Efficacy (TSES)’ measure across countries and provides a synergism between substantive research on teachers’ self-efficacy and the novel methodological approach of exploratory structural equation modeling (ESEM). These challenges include adequately representing the conceptual overlap between the facets of self-efficacy in a measurement model (cross-loadings) and comparing means and factor structures across countries (measurement invariance). On the basis of the OECD Teaching and Learning International Survey (TALIS) 2013 data set comprising 32 countries (N = 164,687), we investigate the effects of cross-loadings in the TSES measurement model on the results of measurement invariance testing and the estimation of relations to external constructs (i.e., working experience, job satisfaction). To further test the robustness of our results, we replicate the 32-countries analyses for three selected sub-groups of countries (i.e., Nordic, East and South-East Asian, and Anglo-Saxon country clusters). For each of the TALIS 2013 participating countries, we found that the factor structure of the self-efficacy measure is better represented by ESEM than by confirmatory factor analysis (CFA) models that do not allow for cross-loadings. For both ESEM and CFA, only metric invariance could be achieved. Nevertheless, invariance levels beyond metric invariance are better achieved with ESEM within selected country clusters. Moreover, the existence of cross-loadings did not affect the relations between the dimensions of teachers’ self-efficacy and external constructs. Overall, this study shows that a conceptual overlap between the facets of self-efficacy exists and can be well-represented by ESEM. We further argue for the cross-cultural generalizability of the corresponding measurement model. PMID:26959236

The Quest for Comparability: Studying the Invariance of the Teachers' Sense of Self-Efficacy (TSES) Measure across Countries.

PubMed

Scherer, Ronny; Jansen, Malte; Nilsen, Trude; Areepattamannil, Shaljan; Marsh, Herbert W

2016-01-01

Teachers' self-efficacy is an important motivational construct that is positively related to a variety of outcomes for both the teachers and their students. This study addresses challenges associated with the commonly used 'Teachers' Sense of Self-Efficacy (TSES)' measure across countries and provides a synergism between substantive research on teachers' self-efficacy and the novel methodological approach of exploratory structural equation modeling (ESEM). These challenges include adequately representing the conceptual overlap between the facets of self-efficacy in a measurement model (cross-loadings) and comparing means and factor structures across countries (measurement invariance). On the basis of the OECD Teaching and Learning International Survey (TALIS) 2013 data set comprising 32 countries (N = 164,687), we investigate the effects of cross-loadings in the TSES measurement model on the results of measurement invariance testing and the estimation of relations to external constructs (i.e., working experience, job satisfaction). To further test the robustness of our results, we replicate the 32-countries analyses for three selected sub-groups of countries (i.e., Nordic, East and South-East Asian, and Anglo-Saxon country clusters). For each of the TALIS 2013 participating countries, we found that the factor structure of the self-efficacy measure is better represented by ESEM than by confirmatory factor analysis (CFA) models that do not allow for cross-loadings. For both ESEM and CFA, only metric invariance could be achieved. Nevertheless, invariance levels beyond metric invariance are better achieved with ESEM within selected country clusters. Moreover, the existence of cross-loadings did not affect the relations between the dimensions of teachers' self-efficacy and external constructs. Overall, this study shows that a conceptual overlap between the facets of self-efficacy exists and can be well-represented by ESEM. We further argue for the cross-cultural generalizability of the corresponding measurement model.

Biomechanical responses of PMHS in moderate-speed rear impacts and development of response targets for evaluating the internal and external biofidelity of ATDS.

PubMed

Kang, Yun-Seok; Bolte, John H; Moorhouse, Kevin; Donnelly, Bruce; Herriott, Rodney; Mallory, Ann

2012-10-01

The objectives of this study were to obtain biomechanical responses of post mortem human subjects (PMHS) by subjecting them to two moderate-speed rear impact sled test conditions (8.5g, 17 km/h; 10.5g, 24 km/h) while positioned in an experimental seat system, and to create biomechanical targets for internal and external biofidelity evaluation of rear impact ATDs. The experimental seat was designed to measure external loads on the head restraint (4 load cells), seat back (6 load cells), and seat pan (4 load cells) such that subject dynamic interaction with the seat could be evaluated. This seat system was capable of simulating the dynamic characteristics of modern vehicle seat backs by considering the moment-rotation properties of a typical passenger vehicle, thus providing a more realistic test environment than using a rigid seat with a non-rotating seat back as done in previous studies. Instrumentation used to measure biomechanical responses of the PMHS included both accelerometers and angular rate sensors (ARS). A total of fourteen sled tests using eight PMHS (males 175.8 ± 6.2 cm of stature and 78.4 ± 7.2 kg of weight) provided data sets of seven PMHS for both test conditions. The biomechanical responses are described at both speeds, and cervical spine injuries are documented. Biomechanical targets are also created for internal and external biofidelity evaluation of rear impact anthropomorphic test devices (ATDs).

Evaluation of the Match External Load in Soccer: Methods Comparison.

PubMed

Castagna, Carlo; Varley, Matthew; Póvoas, Susana C A; D'Ottavio, Stefano

2017-04-01

To test the interchangeability of 2 match-analysis approaches for external-load detection considering arbitrary selected speeds and metabolic power (MP) thresholds in male top-level soccer. Data analyses were performed considering match physical performance of 60 matches (1200 player cases) of randomly selected Spanish, German, and English first-division championship matches (2013-14 season). Match analysis was performed with a validated semiautomated multicamera system operating at 25 Hz. During a match, players covered 10,673 ± 348 m, of which 1778 ± 208 m and 2759 ± 241 m were performed at high intensity, as measured using speed (≥16 km/h, HI) and metabolic power (≥20 W/kg, MPHI) notations. High-intensity notations were nearly perfectly associated (r = .93, P < .0001). A huge method bias (980.63 ± 87.82 m, d = 11.67) was found when considering MPHI and HI. Very large correlations were found between match total distance covered and MPHI (r = .84, P < .0001) and HI (r = .74, P < .0001). Player high-intensity decelerations (≥-2 m/s 2 ) were very largely associated with MPHI (r = .73, P < .0001). The speed and MP methods are highly interchangeable at relative level (magnitude rank) but not absolute level (measure magnitude). The 2 physical match-analysis methods can be independently used to track match external load in elite-level players. However, match-analyst decisions must be based on use of a single method to avoid bias in external-load determination.

Relationships Between Internal and External Match-Load Indicators in Soccer Match Officials.

PubMed

Castillo, Daniel; Weston, Matthew; McLaren, Shaun J; Cámara, Jesús; Yanci, Javier

2017-08-01

The aims of this study were to describe the internal and external match loads (ML) of refereeing activity during official soccer matches and to investigate the relationship among the methods of ML quantification across a competitive season. A further aim was to examine the usefulness of differential perceived exertion (dRPE) as a tool for monitoring internal ML in soccer referees. Twenty field referees (FRs) and 43 assistant referees (ARs) participated in the study. Data were collected from 30 competitive matches (FR = 20 observations, AR = 43 observations) and included measures of internal (Edwards' heart-rate-derived training impulse [TRIMP EDW ]) ML, external (total distance covered, distance covered at high speeds, and player load) ML, and ML differentiated ratings of perceived respiratory (sRPE res ) and leg-muscle (sRPE mus ) exertion. Internal and external ML were all greater for FRs than for ARs (-19.7 to -72.5), with differences ranging from very likely very large to most likely extremely large. The relationships between internal-ML and external-ML indicators were, in most cases, unclear for FR (r < .35) and small to moderate for AR (r < .40). The authors found substantial differences between RPE res and RPE mus scores in both FRs (0.6 AU; ±90% confidence limits 0.4 AU) and ARs (0.4; ±0.3). These data demonstrate the multifaceted demands of soccer refereeing and thereby highlight the importance of monitoring both internal and external ML. Moreover, dRPE represents distinct dimensions of effort and may be useful in monitoring soccer referees' ML during official matches.

Distraction and mind-wandering under load.

PubMed

Forster, Sophie

2013-01-01

Attention research over the last several decades has provided rich insights into the determinants of distraction, including distractor characteristics, task features, and individual differences. Load Theory represented a particularly important breakthrough, highlighting the critical role of the level and nature of task-load in determining both the efficiency of distractor rejection and the stage of processing at which this occurs. However, until recently studies of distraction were restricted to those measuring rather specific forms of distraction by external stimuli which I argue that, although intended to be irrelevant, were in fact task-relevant. In daily life, attention may be distracted by a wide range of stimuli, which may often be entirely unrelated to any task being performed, and may include not only external stimuli but also internally generated stimuli such as task-unrelated thoughts. This review outlines recent research examining these more general, entirely task-irrelevant, forms of distraction within the framework of Load Theory. I discuss the relation between different forms of distraction, and the universality of load effects across different distractor types and individuals.

Quantitative structure-property relationship modeling of remote liposome loading of drugs.

PubMed

Cern, Ahuva; Golbraikh, Alexander; Sedykh, Aleck; Tropsha, Alexander; Barenholz, Yechezkel; Goldblum, Amiram

2012-06-10

Remote loading of liposomes by trans-membrane gradients is used to achieve therapeutically efficacious intra-liposome concentrations of drugs. We have developed Quantitative Structure Property Relationship (QSPR) models of remote liposome loading for a data set including 60 drugs studied in 366 loading experiments internally or elsewhere. Both experimental conditions and computed chemical descriptors were employed as independent variables to predict the initial drug/lipid ratio (D/L) required to achieve high loading efficiency. Both binary (to distinguish high vs. low initial D/L) and continuous (to predict real D/L values) models were generated using advanced machine learning approaches and 5-fold external validation. The external prediction accuracy for binary models was as high as 91-96%; for continuous models the mean coefficient R(2) for regression between predicted versus observed values was 0.76-0.79. We conclude that QSPR models can be used to identify candidate drugs expected to have high remote loading capacity while simultaneously optimizing the design of formulation experiments. Copyright © 2011 Elsevier B.V. All rights reserved.

Assessment of mechanical strain in the intact plantar fascia.

PubMed

Clark, Ross A; Franklyn-Miller, Andrew; Falvey, Eanna; Bryant, Adam L; Bartold, Simon; McCrory, Paul

2009-09-01

A method of measuring tri-axial plantar fascia strain that is minimally affected by external compressive force has not previously been reported. The purpose of this study was to assess the use of micro-strain gauges to examine strain in the different axes of the plantar fascia. Two intact limbs from a thawed, fresh-frozen cadaver were dissected, and a combination of five linear and one three-way rosette gauges were attached to the fascia of the foot and ankle. Strain was assessed during two trials, both consisting of an identical controlled, loaded dorsiflexion. An ICC analysis of the results revealed that the majority of gauge placement sites produced reliable measures (ICC>0.75). Strain mapping of the plantar fascia indicates that the majority of the strain is centrally longitudinal, which provides supportive evidence for finite element model analysis. Although micro-strain gauges do possess the limitation of calibration difficulty, they provide a repeatable measure of fascial strain and may provide benefits in situations that require tri-axial assessment or external compression.

Aerodynamic Loads on an External Store Adjacent to a 45 Degree Sweptback Wing at Mach Numbers from 0.70 to 1.96, Including an Evaluation of Techniques Used

NASA Technical Reports Server (NTRS)

Guy, Lawrence D; Hadaway, William M

1955-01-01

Aerodynamic forces and moments have been obtained in the Langley 9- by 12-inch blowdown tunnel on an external store and on a 45 degree swept-back wing-body combination measured separately at Mach numbers from 0.70 to 1.96. The wing was cantilevered and had an aspect ratio of 4.0; the store was independently sting-mounted and had a Douglas Aircraft Co. (DAC) store shape. The angle of attack range was from -3 degrees to 12 degrees and the Reynolds number (based on wing mean aerodynamic chord) varied from 1.2 x10(6) to 1.7 x 10(6). Wing-body transonic forces and moments have been compared with data of a geometrically similar full-scale model tested in the Langley 16-foot and 8-foot transonic tunnels in order to aid in the evaluation of transonic-tunnel interference. The principal effect of the store, for the position tested, was that of delaying the wing-fuselage pitch-up tendency to higher angles of attack at Mach numbers from 0.70 to 0.90 in a manner similar to that of a wing chord extension. The most critical loading condition on the store was that due to side force, not only because the loads were of large magnitude but also because they were in the direction of least structural strength of the supporting pylon. These side loads were greatest at high angles of attack in the supersonic speed range. Removal of the supporting pylon (or increasing the gap between the store and wing) reduced the values of the variation of side-force coefficientwith angle of attack by about 50 percent at all test Mach numbers, indicating that important reductions in store side force may be realized by proper design or location of the necessary supporting pylon. A change of the store skew angle (nose inboard) was found to relieve the excessive store side loads throughout the Mach number range. It was also determined that the relative position of the fuselage nose to the store can appreciably affect the store side forces at supersonic speeds.

Memory effects on mechanically stimulated electric signal; diversification of stimuli impact on material memory and comments on the observed features

NASA Astrophysics Data System (ADS)

Kyriazis, Panagiotis; Stavrakas, Ilias; Anastasiadis, Cimon; Triantis, Dimos; Stonham, John

2010-05-01

Memory is defined as the ability of marble and generally of brittle geomaterials to retain 'imprints' from previous treatments and to reproduce information about these treatments under certain conditions, by analogy to the memory of human beings. Memory effects have been observed in the evolution of a variety of physical properties like the acoustic emissions of brittle materials during fracture. The existence of memory effects for the mechanically stimulated electric signal, either by Pressure (PSC) or by Bending (BSC), is examined in this work, alongside with an attempt to distinguish between the two different manifestations of 'memory' based on the electrification mechanism that is triggered at different levels of externally applied load on samples. Having identified two main mechanisms (i.e. the dynamic and the cracking) and following the human memory model, we suggest the separation of memory of a material specimen into two levels i.e. the short or temporary and long or permanent memory. For the observation and analysis of the short memory of brittle materials we have conducted experiments using the PSC technique in marble specimens. The materials are imposed to cyclic stepwise loading of the same level, scheme and direction (axial stress - unchanged position of material) in order to comply with the conditions that are proposed as suitable for memory effects study by other researchers. We have also conducted experimental tests of cyclic high level stepwise loading on amphibolite rock specimens in order to verify and study the existence of permanent memory effects. Modelling the signal recordings and studying the effects of memory on the signals, we have identified certain trends manifestation for the two types of memory that are summarised to the following points. (a) Both types of memory influence the PSC peaks evolution (exponential decrease) in cyclic loadings of the same level. (b) Permanent memory cannot be erased and affects PSC signal permanently and severely. (c) The short memory has temporary influence on the PSC signal and the impacts on the signal are milder. The main properties of the PSC signal, which are affected by the existence of memory, converge to an inertial attitude of the material to the same stimuli and they are quite common with the properties of other fracture induced signals (i.e. AE). Namely, they are the following: (a) The PSC peak evolution over loading cycles is a changing signal property either in the case of permanent or of temporary memory, with respect to the time interval between events, especially in the latter case. (b) The decrease of the dissipated electric energy during cyclic loading tests. (c) The PSC slower relaxation in each loading, quantified by the relaxation process parameters evolution. (d) The PSC signal response delay in each loading cycle increase The existence of memory effects on the mechanically stimulated electric signal is an indication that information about the deformation history (paleostresses) of the material reside inside the material. Under certain conditions such information can be revealed by analysis of the PSC signal response to specific external mechanical triggering.

Workplace stress, job satisfaction, job performance, and turnover intention of health care workers in rural Taiwan.

PubMed

Chao, Ming-Che; Jou, Rong-Chang; Liao, Cing-Chu; Kuo, Chung-Wei

2015-03-01

Workplace stress (WS) has been found to affect job satisfaction (JS), performance, and turnover intentions (TIs) in developed countries, but there is little evidence from other countries and especially rural areas. In rural Taiwan, especially, there is an insufficient health care workforce, and the situation is getting worse. To demonstrate the relationship, we used a cross-sectional structured questionnaire, and data from 344 licensed professionals in 1 rural regional hospital were analyzed using the structural equation model. The results showed that WS had a positive effect on both TI and job performance (JP) but a negative effect on satisfaction. JS did improve performance. For the staff with an external locus of control, stress affected JP and satisfaction significantly. For the staff with lower perceived job characteristics, JS affected performance significantly. The strategies to decrease stress relating to work load, role conflict, family factors, and working environment should be focused and implemented urgently to lower the turnover rate of health care workers in rural Taiwan. © 2013 APJPH.

Maternal regulation of child affect in externalizing and typically-developing children.

PubMed

Lougheed, Jessica P; Hollenstein, Tom; Lichtwarck-Aschoff, Anna; Granic, Isabela

2015-02-01

Temporal contingencies between children's affect and maternal behavior play a role in the development of children's externalizing problems. The goal of the current study was to use a microsocial approach to compare dyads with externalizing dysregulation (N =191) to healthy controls (N = 54) on maternal supportive regulation of children's negative and positive affect. Children were between the ages of 8 and 12 years. Mother-child dyads participated in conflict and positive discussions, and child affect and maternal supportive affect regulation were coded in real time. First, no group differences on overall levels of mother supportive regulation or child affect were found. Second, three event history analyses in a 2-level Cox hazard regression framework were used to predict the hazard rate of (a) maternal supportiveness, and of children's transitions (b) out of negative affect and (c) into positive affect. The hazard rate of maternal supportiveness, regardless of child affect, was not different between groups. However, as expected, the likelihood of mothers' supportive responses to children's negative affect was lower in externalizing than comparison dyads. In addition, children with externalizing problems were significantly less likely than typically developing children to transition out of negative affect in response to maternal supportiveness. The likelihood of both typically developing children and children with externalizing problems transitioning into positive affect were not related to specific occurrences of maternal supportiveness. Results of the current study show the importance of temporal dynamics in mother-child interactions in the emergence of children's externalizing problems. PsycINFO Database Record (c) 2015 APA, all rights reserved.

Positional Differences in External On-Field Load During Specific Drill Classifications Over a Professional Rugby League Preseason.

PubMed

Cummins, Cloe; McLean, Blake; Halaki, Mark; Orr, Rhonda

2017-07-01

To quantify the external training loads of positional groups in preseason training drills. Thirty-three elite rugby league players were categorized into 1 of 4 positional groups: outside backs (n = 9), adjustables (n = 9), wide-running forwards (n = 9), and hit-up forwards (n = 6). Data for 8 preseason weeks were collected using microtechnology devices. Training drills were classified based on drill focus: speed and agility, conditioning, and generic and positional skills. Total, high-speed, and very-high-speed distance decreased across the preseason in speed and agility (moderate, small, and small, respectively), conditioning (large, large, and small) and generic skills (large, large, and large). The duration of speed and generic skills also decreased (77% and 48%, respectively). This was matched by a concomitant increase in total distance (small), high-speed running (small), very-high-speed running (moderate), and 2-dimensional (2D) BodyLoad (small) demands in positional skills. In positional skills, hit-up forwards (1240 ± 386 m) completed less very-high-speed running than outside backs (2570 ± 1331 m) and adjustables (2121 ± 1163 m). Hit-up forwards (674 ± 253 AU) experienced greater 2D BodyLoad demands than outside backs (432 ± 230 AU, P = .034). In positional drills, hit-up forwards experienced greater relative 2D BodyLoad demands than outside backs (P = .015). Conversely, outside backs experienced greater relative high- (P = .007) and very-high-speed-running (P < .001) demands than hit-up forwards. Significant differences were observed in training loads between positional groups during positional skills but not in speed and agility, conditioning, and generic skills. This work also highlights the importance of different external-load parameters to adequately quantify workload across different positional groups.

Design of responsive materials using topologically interlocked elements

NASA Astrophysics Data System (ADS)

Molotnikov, A.; Gerbrand, R.; Qi, Y.; Simon, G. P.; Estrin, Y.

2015-02-01

In this work we present a novel approach to designing responsive structures by segmentation of monolithic plates into an assembly of topologically interlocked building blocks. The particular example considered is an assembly of interlocking osteomorphic blocks. The results of this study demonstrate that the constraining force, which is required to hold the blocks together, can be viewed as a design parameter that governs the bending stiffness and the load bearing capacity of the segmented structure. In the case where the constraining forces are provided laterally using an external frame, the maximum load the assembly can sustain and its stiffness increase linearly with the magnitude of the lateral load applied. Furthermore, we show that the segmented plate with integrated shape memory wires employed as tensioning cables can act as a smart structure that changes its flexural stiffness and load bearing capacity in response to external stimuli, such as heat generated by the switching on and off an electric current.

Sex-Based Differences in Knee Kinetics With Anterior Cruciate Ligament Strain on Cadaveric Impact Simulations

PubMed Central

Schilaty, Nathan D.; Bates, Nathaniel A.; Nagelli, Christopher; Krych, Aaron J.; Hewett, Timothy E.

2018-01-01

Background: Females are at an increased risk of sustaining noncontact knee ligament injuries as compared with their male counterparts. The kinetics that load the anterior cruciate ligament (ACL) are still under dispute in the literature. Purpose/Hypothesis: The purpose of this study was to determine whether there are differences in knee kinetics between the sexes that lead to greater ACL strain in females when similar external loads are applied during a simulated drop vertical jump landing task. It was hypothesized that female limbs would demonstrate significant differences in knee abduction moment that predispose females to ACL injury when compared with males. Study Design: Controlled laboratory study. Methods: Motion analysis data of 67 athletes who performed a drop vertical jump were collected. The kinematic and kinetic data were used to categorize tertiles of relative risk, and these values were input into a cadaveric impact simulator to assess ligamentous loads during the simulated landing task. Uni- and multiaxial load cells and differential variable reluctance transducer strain sensors were utilized to collect kinetic data and maximum ACL strain for analysis. Conditions of external loads applied to the cadaveric limbs were systematically varied and randomized. Data were analyzed with 2-way repeated-measures analysis of variance and the Fisher exact test. Results: Five kinetic parameters were evaluated. Of the 5 kinetic variables, only knee abduction moment (KAM) demonstrated significant differences in females as compared with males (F 1,136 = 4.398, P = .038). When normalized to height and weight, this difference between males and females increased in significance (F 1,136 = 7.155, P = .008). Compared with males, females exhibited a 10.3-N·m increased knee abduction torque at 66 milliseconds postimpact and a 22.3-N·m increased abduction torque at 100 milliseconds postimpact. For loading condition, the condition of “maximum ACL strain” demonstrated a maximum difference of 54.3-N·m increased abduction torque and 74.5-N·m increased abduction torque at 66 milliseconds postimpact. Conclusion: Under the tested conditions, increased external loads led to increased medial knee translation force, knee abduction moment, and external knee moment. Females exhibited greater forces and moments at the knee, especially at KAM, when loaded in similar conditions. As these KAM loads are associated with increased load and strain on the ACL, the sex-based differences observed in the present study may account for a portion of the underlying mechanics that predispose females to ACL injury as compared with males in a controlled simulated athletic task. Clinical Relevance: KAM increases strain to the ACL under clinically representative loading. Additionally, this work establishes the biomechanical characteristics of knee loading between sexes. PMID:29568787

Sex-Based Differences in Knee Kinetics With Anterior Cruciate Ligament Strain on Cadaveric Impact Simulations.

PubMed

Schilaty, Nathan D; Bates, Nathaniel A; Nagelli, Christopher; Krych, Aaron J; Hewett, Timothy E

2018-03-01

Females are at an increased risk of sustaining noncontact knee ligament injuries as compared with their male counterparts. The kinetics that load the anterior cruciate ligament (ACL) are still under dispute in the literature. The purpose of this study was to determine whether there are differences in knee kinetics between the sexes that lead to greater ACL strain in females when similar external loads are applied during a simulated drop vertical jump landing task. It was hypothesized that female limbs would demonstrate significant differences in knee abduction moment that predispose females to ACL injury when compared with males. Controlled laboratory study. Motion analysis data of 67 athletes who performed a drop vertical jump were collected. The kinematic and kinetic data were used to categorize tertiles of relative risk, and these values were input into a cadaveric impact simulator to assess ligamentous loads during the simulated landing task. Uni- and multiaxial load cells and differential variable reluctance transducer strain sensors were utilized to collect kinetic data and maximum ACL strain for analysis. Conditions of external loads applied to the cadaveric limbs were systematically varied and randomized. Data were analyzed with 2-way repeated-measures analysis of variance and the Fisher exact test. Five kinetic parameters were evaluated. Of the 5 kinetic variables, only knee abduction moment (KAM) demonstrated significant differences in females as compared with males ( F 1,136 = 4.398, P = .038). When normalized to height and weight, this difference between males and females increased in significance ( F 1,136 = 7.155, P = .008). Compared with males, females exhibited a 10.3-N·m increased knee abduction torque at 66 milliseconds postimpact and a 22.3-N·m increased abduction torque at 100 milliseconds postimpact. For loading condition, the condition of "maximum ACL strain" demonstrated a maximum difference of 54.3-N·m increased abduction torque and 74.5-N·m increased abduction torque at 66 milliseconds postimpact. Under the tested conditions, increased external loads led to increased medial knee translation force, knee abduction moment, and external knee moment. Females exhibited greater forces and moments at the knee, especially at KAM, when loaded in similar conditions. As these KAM loads are associated with increased load and strain on the ACL, the sex-based differences observed in the present study may account for a portion of the underlying mechanics that predispose females to ACL injury as compared with males in a controlled simulated athletic task. KAM increases strain to the ACL under clinically representative loading. Additionally, this work establishes the biomechanical characteristics of knee loading between sexes.

Multi-frequency klystron designed for high efficiency

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jensen, Aaron

A multi-frequency klystron has an electron gun which generates a beam, a circuit of bunch-align-collect (BAC) tuned cavities that bunch the beam and amplify an RF signal, a collector where the beam is collected and dumped, and a standard output cavity and waveguide coupled to a window to output RF power at a fundamental mode to an external load. In addition, the klystron has additional bunch-align-collect (BAC) cavities tuned to a higher harmonic frequency, and a harmonic output cavity and waveguide coupled via a window to an additional external load.

Two-loads Method for Distinguishing among the Muscle Force, Velocity, and Power Producing Capacities

PubMed Central

Jaric, Slobodan

2016-01-01

It has been generally accepted that muscles could have different mechanical capacities, such as those for producing high force (F), velocity (V), and power (P) outputs. Nevertheless, the standard procedures of the evaluation of muscle function both in research and routine testing are typically conducted under a single mechanical condition, such as under a single external load. Therefore, the observed outcomes do not allow for distinguishing among the different muscle capacities. As a result, the outcomes of most of the routine testing procedures have been of limited informational value, while a number of debated issues in research have originated from arbitrarily interpreted experimental findings regarding specific muscle capacities. A solution for the discussed problem could be based on the approximately linear and exceptionally strong F-V relationship typically observed from various functional tasks performed under different external loads. These findings allow for the 'two-loads method' proposed in this Current Opinion: the functional movement tasks (e.g., maximum jumping, cycling, running, pushing, lifting, or throwing) should be tested against just 2 distinctive external loads. Namely, the F-V relationship determined by 2 pairs of the F and V data could provide the parameters depicting the maximum F (i.e., the F-intercept), V (V-intercept), and P (calculated from the product of F and V) output of the tested muscles. Therefore, the proposed two-loads method applied in both research and routine testing could provide a deeper insight into the mechanical properties and function of the tested muscles and resolve a number of debated issues in the literature. PMID:27075326

Ratings of perceived exertion by women with internal or external locus of control.

PubMed

Hassmén, P; Koivula, N

1996-10-01

Ratings of perceived exertion are frequently used to estimate the strain and effort experienced subjectively by individuals during various forms of physical activity. A number of factors, both physiological and psychological in origin, have been suggested to work as modifiers of the exertion perceived by the individual. It has been reported in nonsport-related research that individuals with an internal locus of control seem to pay more attention to relevant information and use the available information more adequately than individuals with an external locus of control. The reputed inferior information-processing abilities of externals compared with internals could possibly also influence the ratings of perceived exertion, with externals being less accurate in their ratings. Whether locus of control might be such a factor was investigated. Fifty women worked on an ergometer cycle at four different work loads. The results showed statistically significant differences in subjective ratings of perceived exertion between externals and internals, especially at heavier work loads. Such differences might be because of unequal information-processing abilities, as the observed discrepancies occurred at higher work intensities, when more cues are available for processing.

Evaluation of stability of interface between CCM (Co-Cr-Mo) UCLA abutment and external hex implant.

PubMed

Yoon, Ki-Joon; Park, Young-Bum; Choi, Hyunmin; Cho, Youngsung; Lee, Jae-Hoon; Lee, Keun-Woo

2016-12-01

The purpose of this study is to evaluate the stability of interface between Co-Cr-Mo (CCM) UCLA abutment and external hex implant. Sixteen external hex implant fixtures were assigned to two groups (CCM and Gold group) and were embedded in molds using clear acrylic resin. Screw-retained prostheses were constructed using CCM UCLA abutment and Gold UCLA abutment. The external implant fixture and screw-retained prostheses were connected using abutment screws. After the abutments were tightened to 30 Ncm torque, 5 kg thermocyclic functional loading was applied by chewing simulator. A target of 1.0 × 10 6 cycles was applied. After cyclic loading, removal torque values were recorded using a driving torque tester, and the interface between implant fixture and abutment was evaluated by scanning electronic microscope (SEM). The means and standard deviations (SD) between the CCM and Gold groups were analyzed with independent t-test at the significance level of 0.05. Fractures of crowns, abutments, abutment screws, and fixtures and loosening of abutment screws were not observed after thermocyclic loading. There were no statistically significant differences at the recorded removal torque values between CCM and Gold groups ( P >.05). SEM analysis revealed that remarkable wear patterns were observed at the abutment interface only for Gold UCLA abutments. Those patterns were not observed for other specimens. Within the limit of this study, CCM UCLA abutment has no statistically significant difference in the stability of interface with external hex implant, compared with Gold UCLA abutment.

A case study on the structural assessment of fire damaged building

NASA Astrophysics Data System (ADS)

Osman, M. H.; Sarbini, N. N.; Ibrahim, I. S.; Ma, C. K.; Ismail, M.; Mohd, M. F.

2017-11-01

This paper presents a case study on the structural assessment of building damaged by fire and discussed on the site investigations and test results prior to determine the existing condition of the building. The building was on fire for about one hour before it was extinguished. In order to ascertain the integrity of the building, a visual inspection was conducted for all elements (truss, beam, column and wall), followed by non-destructive, load and material tests. The load test was conducted to determine the ability of truss to resist service load, while the material test to determine the residual strength of the material. At the end of the investigation, a structural analysis was carried out to determine the new factor of safety by considering the residual strength. The highlighted was on the truss element due to steel behaviour that is hardly been predicted. Meanwhile, reinforced concrete elements (beam, column and wall) were found externally affected and caused its strength to be considered as sufficient for further used of building. The new factor of safety is equal to 2, considered as the minimum calculated value for the truss member. Therefore, this fire damaged building was found safe and can be used for further application.

The effects of an adopted narrow gait on the external adduction moment at the knee joint during level walking: evidence of asymmetry.

PubMed

Street, Brian D; Gage, William

2013-04-01

The external knee adduction moment is an accurate estimation of the load distribution of the knee and is a valid predictor for the presence, severity and progression rate of medial compartment knee osteoarthritis. Gait modification strategies have been shown to be an effective means of reducing the external adduction moment. The purpose of this study was to test narrow gait as a mechanism to reduce the external adduction moment and investigate if limb dominance affects this pattern. Fifteen healthy male participants (mean age: 23.8 (SD=3.1) years, mean height: 1.8 (SD=0.1) m, and mean body mass: 82.9 (SD=16.1 kg) took part in this study. Five walking trials were performed for each of the three different gait conditions: normal gait, toe-out gait, and narrow gait. Adoption of the narrow gait strategy significantly reduced the early stance phase external knee adduction moment compared to normal and toe-out gait (p<.002). However, it was observed that this reduction only occurred in the non-dominant limb. Gait modification can reduce the external knee adduction moment. However, asymmetrical patterns between the dominant and non-dominant limbs, specifically during gait modification, may attenuate the effectiveness of this intervention. The mechanism of limb dominance and the specific roles of each limb during gait may account for an asymmetrical pattern in the moment arm and center of mass displacement during stance. This new insight into how limb-dominance effects gait modification strategies will be useful in the clinical setting when identifying appropriate patients, when indicating a gait modification strategy and in future research methodology. Copyright © 2013 Elsevier B.V. All rights reserved.

Response of Submerged Macrophyte Communities to External and Internal Restoration Measures in North Temperate Shallow Lakes.

PubMed

Hilt, Sabine; Alirangues Nuñez, Marta M; Bakker, Elisabeth S; Blindow, Irmgard; Davidson, Thomas A; Gillefalk, Mikael; Hansson, Lars-Anders; Janse, Jan H; Janssen, Annette B G; Jeppesen, Erik; Kabus, Timm; Kelly, Andrea; Köhler, Jan; Lauridsen, Torben L; Mooij, Wolf M; Noordhuis, Ruurd; Phillips, Geoff; Rücker, Jacqueline; Schuster, Hans-Heinrich; Søndergaard, Martin; Teurlincx, Sven; van de Weyer, Klaus; van Donk, Ellen; Waterstraat, Arno; Willby, Nigel; Sayer, Carl D

2018-01-01

Submerged macrophytes play a key role in north temperate shallow lakes by stabilizing clear-water conditions. Eutrophication has resulted in macrophyte loss and shifts to turbid conditions in many lakes. Considerable efforts have been devoted to shallow lake restoration in many countries, but long-term success depends on a stable recovery of submerged macrophytes. However, recovery patterns vary widely and remain to be fully understood. We hypothesize that reduced external nutrient loading leads to an intermediate recovery state with clear spring and turbid summer conditions similar to the pattern described for eutrophication. In contrast, lake internal restoration measures can result in transient clear-water conditions both in spring and summer and reversals to turbid conditions. Furthermore, we hypothesize that these contrasting restoration measures result in different macrophyte species composition, with added implications for seasonal dynamics due to differences in plant traits. To test these hypotheses, we analyzed data on water quality and submerged macrophytes from 49 north temperate shallow lakes that were in a turbid state and subjected to restoration measures. To study the dynamics of macrophytes during nutrient load reduction, we adapted the ecosystem model PCLake. Our survey and model simulations revealed the existence of an intermediate recovery state upon reduced external nutrient loading, characterized by spring clear-water phases and turbid summers, whereas internal lake restoration measures often resulted in clear-water conditions in spring and summer with returns to turbid conditions after some years. External and internal lake restoration measures resulted in different macrophyte communities. The intermediate recovery state following reduced nutrient loading is characterized by a few macrophyte species (mainly pondweeds) that can resist wave action allowing survival in shallow areas, germinate early in spring, have energy-rich vegetative propagules facilitating rapid initial growth and that can complete their life cycle by early summer. Later in the growing season these plants are, according to our simulations, outcompeted by periphyton, leading to late-summer phytoplankton blooms. Internal lake restoration measures often coincide with a rapid but transient colonization by hornworts, waterweeds or charophytes. Stable clear-water conditions and a diverse macrophyte flora only occurred decades after external nutrient load reduction or when measures were combined.

Applying torque to the Escherichia coli flagellar motor using magnetic tweezers.

PubMed

van Oene, Maarten M; Dickinson, Laura E; Cross, Bronwen; Pedaci, Francesco; Lipfert, Jan; Dekker, Nynke H

2017-03-07

The bacterial flagellar motor of Escherichia coli is a nanoscale rotary engine essential for bacterial propulsion. Studies on the power output of single motors rely on the measurement of motor torque and rotation under external load. Here, we investigate the use of magnetic tweezers, which in principle allow the application and active control of a calibrated load torque, to study single flagellar motors in Escherichia coli. We manipulate the external load on the motor by adjusting the magnetic field experienced by a magnetic bead linked to the motor, and we probe the motor's response. A simple model describes the average motor speed over the entire range of applied fields. We extract the motor torque at stall and find it to be similar to the motor torque at drag-limited speed. In addition, use of the magnetic tweezers allows us to force motor rotation in both forward and backward directions. We monitor the motor's performance before and after periods of forced rotation and observe no destructive effects on the motor. Our experiments show how magnetic tweezers can provide active and fast control of the external load while also exposing remaining challenges in calibration. Through their non-invasive character and straightforward parallelization, magnetic tweezers provide an attractive platform to study nanoscale rotary motors at the single-motor level.

Selective effects of weight and inertia on maximum lifting.

PubMed

Leontijevic, B; Pazin, N; Kukolj, M; Ugarkovic, D; Jaric, S

2013-03-01

A novel loading method (loading ranged from 20% to 80% of 1RM) was applied to explore the selective effects of externally added simulated weight (exerted by stretched rubber bands pulling downward), weight+inertia (external weights added), and inertia (covariation of the weights and the rubber bands pulling upward) on maximum bench press throws. 14 skilled participants revealed a load associated decrease in peak velocity that was the least associated with an increase in weight (42%) and the most associated with weight+inertia (66%). However, the peak lifting force increased markedly with an increase in both weight (151%) and weight+inertia (160%), but not with inertia (13%). As a consequence, the peak power output increased most with weight (59%), weight+inertia revealed a maximum at intermediate loads (23%), while inertia was associated with a gradual decrease in the peak power output (42%). The obtained findings could be of importance for our understanding of mechanical properties of human muscular system when acting against different types of external resistance. Regarding the possible application in standard athletic training and rehabilitation procedures, the results speak in favor of applying extended elastic bands which provide higher movement velocity and muscle power output than the usually applied weights. © Georg Thieme Verlag KG Stuttgart · New York.

Applying torque to the Escherichia coli flagellar motor using magnetic tweezers

PubMed Central

van Oene, Maarten M.; Dickinson, Laura E.; Cross, Bronwen; Pedaci, Francesco; Lipfert, Jan; Dekker, Nynke H.

2017-01-01

The bacterial flagellar motor of Escherichia coli is a nanoscale rotary engine essential for bacterial propulsion. Studies on the power output of single motors rely on the measurement of motor torque and rotation under external load. Here, we investigate the use of magnetic tweezers, which in principle allow the application and active control of a calibrated load torque, to study single flagellar motors in Escherichia coli. We manipulate the external load on the motor by adjusting the magnetic field experienced by a magnetic bead linked to the motor, and we probe the motor’s response. A simple model describes the average motor speed over the entire range of applied fields. We extract the motor torque at stall and find it to be similar to the motor torque at drag-limited speed. In addition, use of the magnetic tweezers allows us to force motor rotation in both forward and backward directions. We monitor the motor’s performance before and after periods of forced rotation and observe no destructive effects on the motor. Our experiments show how magnetic tweezers can provide active and fast control of the external load while also exposing remaining challenges in calibration. Through their non-invasive character and straightforward parallelization, magnetic tweezers provide an attractive platform to study nanoscale rotary motors at the single-motor level. PMID:28266562

Changes in the gait characteristics caused by external load, ground slope and velocity variation

NASA Astrophysics Data System (ADS)

Mrozowski, Jerzy; Awrejcewicz, Jan

2011-05-01

The complexity of the human gait manifests itself by lots of parameters that can evoke different changes in the walking manner. They can be divided into two groups: inherent, like anthropometric features or peculiar psychomotor type, and those related to the external conditions. The aim of the paper is to analyze the influence of three parameters, i.e. external load, ground slope and gait velocity, on the locomotion characteristics and the gait stability. Within the framework of investigations for different values of the mentioned parameters a film registration of the trajectories of selected kinematic nodes during some gait cycles has been carried out. The obtained data was a subject of numerical calculation aimed at extracting the essential properties of the principal gait characteristics.

Benthic-planktonic coupling, regime shifts, and whole-lake primary production in shallow lakes.

PubMed

Genkai-Kato, Motomi; Vadeboncoeur, Yvonne; Liboriussen, Lone; Jeppesen, Erik

2012-03-01

Alternative stable states in shallow lakes are typically characterized by submerged macrophyte (clear-water state) or phytoplankton (turbid state) dominance. However, a clear-water state may occur in eutrophic lakes even when macrophytes are absent. To test whether sediment algae could cause a regime shift in the absence of macrophytes, we developed a model of benthic (periphyton) and planktonic (phytoplankton) primary production using parameters derived from a shallow macrophyte-free lake that shifted from a turbid to a clear-water state following fish removal (biomanipulation). The model includes a negative feedback effect of periphyton on phosphorus (P) release from sediments. This in turn induces a positive feedback between phytoplankton production and P release. Scenarios incorporating a gradient of external P loading rates revealed that (1) periphyton and phytoplankton both contributed substantially to whole-lake production over a broad range of external P loading in a clear-water state; (2) during the clear-water state, the loss of benthic production was gradually replaced by phytoplankton production, leaving whole-lake production largely unchanged; (3) the responses of lakes to biomanipulation and increased external P loading were both dependent on lake morphometry; and (4) the capacity of periphyton to buffer the effects of increased external P loading and maintain a clear-water state was highly sensitive to relationships between light availability at the sediment surface and the of P release. Our model suggests a mechanism for the persistence of alternative states in shallow macrophyte-free lakes and demonstrates that regime shifts may trigger profound changes in ecosystem structure and function.

Stress analysis under component relative interference fit

NASA Technical Reports Server (NTRS)

Taylor, C. M.

1978-01-01

Finite-element computer program enables analysis of distortions and stresses occurring in components having relative interference. Program restricts itself to simple elements and axisymmetric loading situations. External inertial and thermal loads may be applied in addition to forces arising from interference conditions.

A comparison of methods to quantify the in-season training load of professional soccer players.

PubMed

Scott, Brendan R; Lockie, Robert G; Knight, Timothy J; Clark, Andrew C; Janse de Jonge, Xanne A K

2013-03-01

To compare various measures of training load (TL) derived from physiological (heart rate [HR]), perceptual (rating of perceived exertion [RPE]), and physical (global positioning system [GPS] and accelerometer) data during in-season field-based training for professional soccer. Fifteen professional male soccer players (age 24.9 ± 5.4 y, body mass 77.6 ± 7.5 kg, height 181.1 ± 6.9 cm) were assessed in-season across 97 individual training sessions. Measures of external TL (total distance [TD], the volume of low-speed activity [LSA; <14.4 km/h], high-speed running [HSR; >14.4 km/h], very high-speed running [VHSR; >19.8 km/h], and player load), HR and session-RPE (sRPE) scores were recorded. Internal TL scores (HR-based and sRPE-based) were calculated, and their relationships with measures of external TL were quantified using Pearson product-moment correlations. Physical measures of TD, LSA volume, and player load provided large, significant (r = .71-.84; P < .01) correlations with the HR-based and sRPE-based methods. Volume of HSR and VHSR provided moderate to large, significant (r = .40-.67; P < .01) correlations with measures of internal TL. While the volume of HSR and VHSR provided significant relationships with internal TL, physical-performance measures of TD, LSA volume, and player load appear to be more acceptable indicators of external TL, due to the greater magnitude of their correlations with measures of internal TL.

Effects of heat and moisture on fiberglass composite materials in the load carrying and non-load carrying conditions

NASA Astrophysics Data System (ADS)

McClurg, Jack Albert

The objective set forth in this study was to thoroughly document the effects of heat, moisture, and loading conditions on a variety of pultruded unidirectional fiberglass reinforced composite materials. This study incorporated the use of two environmental control chambers and two water immersion tanks in order to provide the necessary range of environmental exposure conditions. A set of specially designed stainless steel loading fixtures was produced in order to introduce the factor of external loading of the specimens while exposed to the predetermined environmental condition and how that would affect the mechanical and physical properties in question. The properties of interest were the flexural strength (determined using the three-point flexural bending method), flexural modulus (determined using the three-point flexural bending method), and glass transition temperature of the material (determined using differential scanning calorimetry). Other data that was noted during the conditioning and testing of the specimens was the break type (flexural tension, compression, shear, etc...), the change in dimensions (prior to exposure vs. after exposure), and the change in weight (prior to exposure vs. after exposure). Using all of the information that was obtained from this study, a more detailed understanding of how and why fiberglass reinforced materials react the way they do when exposed to moisture and elevated temperature was drawn. This study is different from most others in that it explores the interactions of three independent variables (heat, moisture, and loading condition) on three different fiberglass reinforced composite systems (epoxy, vinylester, and polyester resin).

Application of a Three-Dimensional Water Quality Model as a Decision Support Tool for the Management of Land-Use Changes in the Catchment of an Oligotrophic Lake

NASA Astrophysics Data System (ADS)

Trolle, Dennis; Spigel, Bob; Hamilton, David P.; Norton, Ned; Sutherland, Donna; Plew, David; Allan, Mathew G.

2014-09-01

While expansion of agricultural land area and intensification of agricultural practices through irrigation and fertilizer use can bring many benefits to communities, intensifying land use also causes more contaminants, such as nutrients and pesticides, to enter rivers, lakes, and groundwater. For lakes such as Benmore in the Waitaki catchment, South Island, New Zealand, an area which is currently undergoing agricultural intensification, this could potentially lead to marked degradation of water clarity as well as effects on ecological, recreational, commercial, and tourism values. We undertook a modeling study to demonstrate science-based options for consideration of agricultural intensification in the catchment of Lake Benmore. Based on model simulations of a range of potential future nutrient loadings, it is clear that different areas within Lake Benmore may respond differently to increased nutrient loadings. A western arm (Ahuriri) could be most severely affected by land-use changes and associated increases in nutrient loadings. Lake-wide annual averages of an eutrophication indicator, the trophic level index (TLI) were derived from simulated chlorophyll a, total nitrogen, and total phosphorus concentrations. Results suggest that the lake will shift from oligotrophic (TLI = 2-3) to eutrophic (TLI = 4-5) as external loadings are increased eightfold over current baseline loads, corresponding to the potential land-use intensification in the catchment. This study provides a basis for use of model results in a decision-making process by outlining the environmental consequences of a series of land-use management options, and quantifying nutrient load limits needed to achieve defined trophic state objectives.

Development of emergency department load relief area--gauging benefits in empirical terms.

PubMed

Rasheed, Farrukh; Lee, Young Hoon; Kim, Seung Ho; Park, In Cheol

2012-12-01

The primary goal of this investigation was to develop a simulation model to evaluate the various internal and external factors affecting patient flow and crowding in the emergency department (ED). In addition, a few recommendations are proposed to reconfigure the patient flow to improve ED capacity while maintaining service quality. In this research, we present a simulation study conducted in the ED at the "S Hospital" located in Seoul. Based on patient flow data and process analysis, a simulation model of patient throughput in the ED has been developed. We evaluated simulations of diverting the specific patient load in the light of our proposed recommendations to a separately managed area named as the ED load relief area (ED-LRA) and analyzing potential effects on overall length of stay (LOS) and waiting time (WT). What-if analyses have been proposed to identify key issues and investigate the improvements as per our proposed recommendations. The simulation results suggest that specific patient load diversion is needed to ensure desired outcomes. With the diversion of specific patient load to ED-LRA, there is a reduction of 40.60% in mean LOS and 42.5% in WT with improved resource utilization. As a result, opening of an ED-LRA is justified. Real-world systems are often too intricate for analytical models and often too expensive to trial with directly. Simulation models allow the modeling of this intricacy and enable experimentation to make inferences about how the actual system might perform. Our simulation study modeled that diverting the specific patient load to ED-LRA produced an improvement in overall ED's LOS and WT.

Handball load and shoulder injury rate: a 31-week cohort study of 679 elite youth handball players.

PubMed

Møller, M; Nielsen, R O; Attermann, J; Wedderkopp, N; Lind, M; Sørensen, H; Myklebust, G

2017-02-01

Knowledge of injury patterns, an essential step towards injury prevention, is lacking in youth handball. To investigate if an increase in handball load is associated with increased shoulder injury rates compared with a minor increase or decrease, and if an association is influenced by scapular control, isometric shoulder strength or glenohumeral range of motion (ROM). 679 players (14-18 years) provided weekly reports on shoulder injury and handball load (training and competition hours) over 31 weeks using the SMS, phone and medical examination system. Handball load in a given week was categorised into (1) <20% increase or decrease (reference), (2) increase between 20% and 60% and (3) increase >60% relative to the weekly average amount of handball load the preceding 4 weeks. Assessment of shoulder isometric rotational and abduction strength, ROM and scapular control was performed at baseline and midseason. An increase in handball load by >60% was associated with greater shoulder injury rate (HR 1.91; 95% CI 1.00 to 3.70, p=0.05) compared with the reference group. The effect of an increase in handball load between 20% and 60% was exacerbated among players with reduced external rotational strength (HR 4.0; 95% CI 1.1 to 15.2, p=0.04) or scapular dyskinesis (HR 4.8; 95% CI 1.3 to 18.3, p=0.02). Reduced external rotational strength exacerbated the effect of an increase above 60% (HR 4.2; 95% CI 1.4 to 12.8, p=0.01). A large increase in weekly handball load increases the shoulder injury rate in elite youth handball players; particularly, in the presence of reduced external rotational strength or scapular dyskinesis. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

Magnetic Bead Actuation of Saccular Hair Cells

NASA Astrophysics Data System (ADS)

Rowland, David; Ramunno-Johnson, Damien; Lee, Jae-Hyun; Cheon, Jinwoo; Bozovic, Dolores

2011-11-01

When decoupled from the overlying membrane, hair bundles of the amphibian sacculus exhibit spontaneous oscillation. To explore the dynamics of this innate motility without an imposed external load, we recorded their oscillations with a high-speed CMOS camera, and applied mechanical manipulation that minimally alters the geometry of an individual hair bundle. We present a technique that utilizes micron-sized magnetic particles to actuate the stereociliary bundle with a magnetized probe. Quasi-steady-state displacements were imposed on freely oscillating bundles. Our data indicate that deflection of the bundle affects both the frequency and the amplitude of the oscillations, with a crossing of the bifurcation that is dependent on the direction and speed of the applied offset.

The use of intramedullary nails in tibiotalocalcaneal arthrodesis.

PubMed

Thomas, Ruth L; Sathe, Vinayak; Habib, Syed I

2012-01-01

Tibiotalocalcaneal arthrodesis is a salvage procedure undertaken for hindfoot problems that affect both the ankle and subtalar joints (eg, two-joint arthritis, severe acute trauma, osteonecrosis of the talus, severe malalignment deformities, significant hindfoot bone loss). Methods of achieving fusion include Steinmann pins, screws, plates, external fixators, and retrograde intramedullary nailing. Retrograde intramedullary nailing provides a load-sharing fixation device with superior biomechanical properties and is an excellent choice for use in tibiotalocalcaneal arthrodesis. This technique can be performed through relatively small incisions. In addition, recent design modifications include the availability of dynamization and the choice of curved or straight nails. Contraindications to the technique include the presence of infection, severe vascular disease, and severe malalignment of the tibia.

Skeletal maturation substantially affects elastic tissue properties in the endosteal and periosteal regions of loaded mice tibiae.

PubMed

Checa, Sara; Hesse, Bernhard; Roschger, Paul; Aido, Marta; Duda, Georg N; Raum, Kay; Willie, Bettina M

2015-07-01

Although it is well known that the bone adapts to changes in the mechanical environment by forming and resorbing the bone matrix, little is known about the influence of mechanical loading on tissue material properties of the pre-existing and newly formed bone. In this study, we analyzed the newly formed and pre-existing tissue after two weeks of controlled in vivo axial compressive loading in tibia of young (10 week-old) and adult (26 week-old) female mice and compared to the control contralateral limb, by means of scanning acoustic microscopy. Additionally, we used quantitative backscattered electron imaging to determine the bone mineral density distribution within the newly formed and pre-existing bone of young mice. No significant differences were found in tissue stiffness or mineral density in the pre-existing bone tissue as a result of external loading. In the endosteal region, 10 and 26 week loaded animals showed a 9% reduction in bone tissue stiffness compared to control animals. An increase of 200% in the mineral apposition rate in this region was observed in both age groups. In the periosteal region, the reduction in bone tissue stiffness and the increase in bone mineral apposition rate as a result of loading were two times higher in the 10 compared to the 26 week old animals. These data suggest that, during growth and skeletal maturation, the response of bone to mechanical loading is a deposition of new bone matrix, where the tissue amount but not its mineral or elastic properties are influenced by animal age. Copyright © 2015 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

An analysis of cross-coupling of a multicomponent jet engine test stand using finite element modeling techniques

NASA Technical Reports Server (NTRS)

Schweikhard, W. G.; Singnoi, W. N.

1985-01-01

A two axis thrust measuring system was analyzed by using a finite a element computer program to determine the sensitivities of the thrust vectoring nozzle system to misalignment of the load cells and applied loads, and the stiffness of the structural members. Three models were evaluated: (1) the basic measuring element and its internal calibration load cells; (2) the basic measuring element and its external load calibration equipment; and (3) the basic measuring element, external calibration load frame and the altitude facility support structure. Alignment of calibration loads was the greatest source of error for multiaxis thrust measuring systems. Uniform increases or decreases in stiffness of the members, which might be caused by the selection of the materials, have little effect on the accuracy of the measurements. It is found that the POLO-FINITE program is a viable tool for designing and analyzing multiaxis thrust measurement systems. The response of the test stand to step inputs that might be encountered with thrust vectoring tests was determined. The dynamic analysis show a potential problem for measuring the dynamic response characteristics of thrust vectoring systems because of the inherently light damping of the test stand.

Joint angles of the ankle, knee, and hip and loading conditions during split squats.

PubMed

Schütz, Pascal; List, Renate; Zemp, Roland; Schellenberg, Florian; Taylor, William R; Lorenzetti, Silvio

2014-06-01

The aim of this study was to quantify how step length and the front tibia angle influence joint angles and loading conditions during the split squat exercise. Eleven subjects performed split squats with an additional load of 25% body weight applied using a barbell. Each subject's movements were recorded using a motion capture system, and the ground reaction force was measured under each foot. The joint angles and loading conditions were calculated using a cluster-based kinematic approach and inverse dynamics modeling respectively. Increases in the tibia angle resulted in a smaller range of motion (ROM) of the front knee and a larger ROM of the rear knee and hip. The external flexion moment in the front knee/hip and the external extension moment in the rear hip decreased as the tibia angle increased. The flexion moment in the rear knee increased as the tibia angle increased. The load distribution between the legs changed < 25% when split squat execution was varied. Our results describing the changes in joint angles and the resulting differences in the moments of the knee and hip will allow coaches and therapists to adapt the split squat exercise to the individual motion and load demands of athletes.

Distraction and Mind-Wandering Under Load

PubMed Central

Forster, Sophie

2013-01-01

Attention research over the last several decades has provided rich insights into the determinants of distraction, including distractor characteristics, task features, and individual differences. Load Theory represented a particularly important breakthrough, highlighting the critical role of the level and nature of task-load in determining both the efficiency of distractor rejection and the stage of processing at which this occurs. However, until recently studies of distraction were restricted to those measuring rather specific forms of distraction by external stimuli which I argue that, although intended to be irrelevant, were in fact task-relevant. In daily life, attention may be distracted by a wide range of stimuli, which may often be entirely unrelated to any task being performed, and may include not only external stimuli but also internally generated stimuli such as task-unrelated thoughts. This review outlines recent research examining these more general, entirely task-irrelevant, forms of distraction within the framework of Load Theory. I discuss the relation between different forms of distraction, and the universality of load effects across different distractor types and individuals. PMID:23734138

Interface Stability Influences Torso Muscle Recruitment and Spinal Load During Pushing Tasks

PubMed Central

LEE, P. J.; GRANATA, K. P.

2006-01-01

Handle or interface design can influence torso muscle recruitment and spinal load during pushing tasks. The objective of the study was to provide insight into the role of interface stability with regard to torso muscle recruitment and biomechanical loads on the spine. Fourteen subjects generated voluntary isometric trunk flexion force against a rigid interface and similar flexion exertions against an unstable interface, which simulated handle design in a cart pushing task. Normalized electromyographic (EMG) activity in the rectus abdominus, external oblique and internal oblique muscles increased with exertion effort. When using the unstable interface, EMG activity in the internal and external oblique muscle groups was greater than when using the rigid interface. Results agreed with trends from a biomechanical model implemented to predict the muscle activation necessary to generate isometric pushing forces and maintain spinal stability when using the two different interface designs. The co-contraction contributed to increased spinal load when using the unstable interface. It was concluded that handle or interface design and stability may influence spinal load and associated risk of musculoskeletal injury during manual materials tasks that involve pushing exertions. PMID:16540437

Apparatus for material tests using an internal loading system in high-pressure gas at room temperature.

PubMed

Imade, M; Fukuyama, S; Yokogawa, K

2008-07-01

A new type of apparatus for material tests using an internal loading system in high-pressure gas up to 100 MPa at room temperature without conventional material testing equipment was developed. The apparatus consists of a high-pressure control system and a pressure vessel, in which a piston is installed in the cylinder of the pressure vessel. The load caused by the pressure difference between spaces separated by the piston in the vessel cylinder is applied on the specimen connected to the piston in the vessel cylinder. The actual load on the specimen is directly measured by an external load cell and the displacement of the specimen is also measured by an external extensometer. As an example of the application of the apparatus, a tensile test on SUS316 stainless steel the Japanese Industrial Standard (JIS) G4303, which is comparable to the type 316 stainless steel ASTM A276, was conducted in 90 MPa hydrogen and argon. Hydrogen showed a marked effect on the tensile property of the material. The hydrogen gas embrittlement of the material was briefly discussed.

Apparatus for material tests using an internal loading system in high-pressure gas at room temperature

NASA Astrophysics Data System (ADS)

Imade, M.; Fukuyama, S.; Yokogawa, K.

2008-07-01

A new type of apparatus for material tests using an internal loading system in high-pressure gas up to 100MPa at room temperature without conventional material testing equipment was developed. The apparatus consists of a high-pressure control system and a pressure vessel, in which a piston is installed in the cylinder of the pressure vessel. The load caused by the pressure difference between spaces separated by the piston in the vessel cylinder is applied on the specimen connected to the piston in the vessel cylinder. The actual load on the specimen is directly measured by an external load cell and the displacement of the specimen is also measured by an external extensometer. As an example of the application of the apparatus, a tensile test on SUS316 stainless steel the Japanese Industrial Standard (JIS) G4303, which is comparable to the type 316 stainless steel ASTM A276, was conducted in 90MPa hydrogen and argon. Hydrogen showed a marked effect on the tensile property of the material. The hydrogen gas embrittlement of the material was briefly discussed.

46 CFR 38.05-3 - Design and construction of pressure vessel type cargo tanks-TB/ALL.

Code of Federal Regulations, 2013 CFR

2013-10-01

... subjected to external loads. Consideration shall also be given to excessive loads that can be imposed on the tanks by their support due to static and dynamic forces under operating conditions or during testing...

46 CFR 38.05-3 - Design and construction of pressure vessel type cargo tanks-TB/ALL.

Code of Federal Regulations, 2011 CFR

2011-10-01

... subjected to external loads. Consideration shall also be given to excessive loads that can be imposed on the tanks by their support due to static and dynamic forces under operating conditions or during testing...

46 CFR 38.05-3 - Design and construction of pressure vessel type cargo tanks-TB/ALL.

Code of Federal Regulations, 2014 CFR

2014-10-01

... subjected to external loads. Consideration shall also be given to excessive loads that can be imposed on the tanks by their support due to static and dynamic forces under operating conditions or during testing...

46 CFR 38.05-3 - Design and construction of pressure vessel type cargo tanks-TB/ALL.

Code of Federal Regulations, 2012 CFR

2012-10-01

... subjected to external loads. Consideration shall also be given to excessive loads that can be imposed on the tanks by their support due to static and dynamic forces under operating conditions or during testing...

Effect of axial tibial torque direction on ACL relative strain and strain rate in an in vitro simulated pivot landing.

PubMed

Oh, Youkeun K; Kreinbrink, Jennifer L; Wojtys, Edward M; Ashton-Miller, James A

2012-04-01

Anterior cruciate ligament (ACL) injuries most frequently occur under the large loads associated with a unipedal jump landing involving a cutting or pivoting maneuver. We tested the hypotheses that internal tibial torque would increase the anteromedial (AM) bundle ACL relative strain and strain rate more than would the corresponding external tibial torque under the large impulsive loads associated with such landing maneuvers. Twelve cadaveric female knees [mean (SD) age: 65.0 (10.5) years] were tested. Pretensioned quadriceps, hamstring, and gastrocnemius muscle-tendon unit forces maintained an initial knee flexion angle of 15°. A compound impulsive test load (compression, flexion moment, and internal or external tibial torque) was applied to the distal tibia while recording the 3D knee loads and tibofemoral kinematics. AM-ACL relative strain was measured using a 3 mm DVRT. In this repeated measures experiment, the Wilcoxon signed-rank test was used to test the null hypotheses with p < 0.05 considered significant. The mean (±SD) peak AM-ACL relative strains were 5.4 ± 3.7% and 3.1 ± 2.8% under internal and external tibial torque, respectively. The corresponding mean (± SD) peak AM-ACL strain rates reached 254.4 ± 160.1%/s and 179.4 ± 109.9%/s, respectively. The hypotheses were supported in that the normalized mean peak AM-ACL relative strain and strain rate were 70 and 42% greater under internal than under external tibial torque, respectively (p = 0.023, p = 0.041). We conclude that internal tibial torque is a potent stressor of the ACL because it induces a considerably (70%) larger peak strain in the AM-ACL than does a corresponding external tibial torque. Copyright © 2011 Orthopaedic Research Society.

Buckling tests of two 4.6-meter-diameter, magnesium ring-stiffened conical shells loaded under external pressure

NASA Technical Reports Server (NTRS)

Anderson, J. K.; DAVIS R. C.

1973-01-01

Two ring-stiffened magnesium conical shells with a 120 deg apex angle and a 4.6-meter diameter were loaded to failure by a uniform external pressure. The cones differed from one another only in the number of internal stiffening rings. Test specimen details, test procedure, and test results are discussed. Both buckling and prebuckling data are compared with appropriate theoretical predictions. Measured strains in skin and rings agreed well with theoretical predictions. Extensive imperfection measurements were made and reported on both cones in the as fabricated condition.

77 FR 56581 - Airworthiness Directives; Sikorsky Aircraft Corporation Helicopters

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-13

... HEC, in this model helicopter that now meets the Category A performance standard. DATES: We must... airworthiness directive (AD) for the Sikorsky Aircraft Corporation (Sikorsky) Model S-92A helicopter, which... external load operations, including human external cargo (HEC), because this model helicopter was not...

Review: magnetically assisted resistance spot welding

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, Y. B.; Li, D. L.; Lin, Z. Q.

2016-02-25

Currently, the use of advanced high strength steels (AHSSs) is the most cost effective means of reducing vehicle body weight and maintaining structural integrity at the same time. However, AHSSs present a big challenge to the traditional resistance spot welding (RSW) widely applied in automotive industries because the rapid heating and cooling procedures during RSW produce hardened weld microstructures, which lower the ductility and fatigue properties of welded joints and raise the probability of interfacial failure under external loads. Changing process parameters or post-weld heat treatment may reduce the weld brittleness, but those traditional quality control methods also increase energymore » consumption and prolong cycle time. In recent years, a magnetically assisted RSW (MA-RSW) method was proposed, in which an externally applied magnetic field would interact with the conduction current to produce a Lorentz force that would affect weld nugget formation. This paper is a review of an experimental MA-RSW platform, the mode of the external magnetic field and the mechanism that controls nugget shape, weld microstructures and joint performance. In conclusion, the advantages of the MA-RSW method in improving the weldability of AHSSs are given, a recent application of the MA-RSW process to light metals is described and the outlook for the MA-RSW process is presented.« less

Development of a relationship between external measurements and reinforcement stress

NASA Astrophysics Data System (ADS)

Brault, Andre; Hoult, Neil A.; Lees, Janet M.

2015-03-01

As many countries around the world face an aging infrastructure crisis, there is an increasing need to develop more accurate monitoring and assessment techniques for reinforced concrete structures. One of the challenges associated with assessing existing infrastructure is correlating externally measured parameters such as crack widths and surface strains with reinforcement stresses as this is dependent on a number of variables. The current research investigates how the use of distributed fiber optic sensors to measure reinforcement strain can be correlated with digital image correlation measurements of crack widths to relate external crack width measurements to reinforcement stresses. An initial set of experiments was undertaken involving a series of small-scale beam specimens tested in three-point bending with variable reinforcement properties. Relationships between crack widths and internal reinforcement strains were observed including that both the diameter and number of bars affected the measured maximum strain and crack width. A model that uses measured crack width to estimate reinforcement strain was presented and compared to the experimental results. The model was found to provide accurate estimates of load carrying capacity for a given crack width, however, the model was potentially less accurate when crack widths were used to estimate the experimental reinforcement strains. The need for more experimental data to validate the conclusions of this research was also highlighted.

Ongoing Capabilities and Developments of Re-Entry Plasma Ground Tests at EADS-ASTRIUM

NASA Technical Reports Server (NTRS)

Jullien, Pierre

2008-01-01

During re-entry, spacecrafts are subjected to extreme thermal loads. On mars, they may go through dust storms. These external heat loads are leading the design of re-entry vehicles or are affecting it for spacecraft facing solid propellant jet stream. Sizing the Thermal Protection System require a good knowledge of such solicitations and means to model and reproduce them on earth. Through its work on European projects, ASTRIUM has developed the full range of competences to deal with such issues. For instance, we have designed and tested the heat-shield of the Huygens probe which landed on Titan. In particular, our plasma generators aim to reproduce a wide variety of re-entry conditions. Heat loads are generated by the huge speed of the probes. Such conditions cannot be fully reproduced. Ground tests focus on reproducing local aerothermal loads by using slower but hotter flows. Our inductive plasma torch enables to test little samples at low TRL. Amongst the arc-jets, one was design to test architecture design of ISS crew return system and others fit more severe re-entry such as sample returns or Venus re-entry. The last developments aimed in testing samples in seeded flows. First step was to design and test the seeding device. Special diagnostics characterizing the resulting flow enabled us to fit it to the requirements.

Nutrient additions by waterfowl to lakes and reservoirs: predicting their effects on productivity and water quality

USGS Publications Warehouse

Manny, Bruce A.; Johnson, W.C.; Wetzel, R.G.

1994-01-01

Lakes and reservoirs provide water for human needs and habitat for aquatic birds. Managers of such waters may ask whether nutrients added by waterfowl degrade water quality. For lakes and reservoirs where primary productivity is limited by phosphorus (P), we developed a procedure that integrates annual P loads from waterfowl and other external sources, applies a nutrient load-response model, and determines whether waterfowl that used the lake or reservoir degraded water quality. Annual P loading by waterfowl can be derived from a figure in this report, using the days per year that each kind spent on any lake or reservoir. In our example, over 6500 Canada geese (Branta canadensis) and 4200 ducks (mostly mallards, Anas platyrhynchos) added 4462 kg of carbon (C), 280 kg of nitrogen (N), and 88 kg of P y-1 to Wintergreen Lake in southwestern Michigan, mostly during their migration. These amounts were 69% of all C, 27% of all N, and 70% of all P that entered the lake from external sources. Loads from all external sources totaled 840 mg P m-2 y-1. Application of a nutrient load-response model to this concentration, the hydraulic load (0.25 m y-1), and the water residence time (9.7 y) of Wintergreen Lake yielded an average annual concentration of total P in the lake of 818 mg m-3 that classified the lake as hypertrophic. This trophic classification agreed with independent measures of primary productivity, chlorophyll-a, total P, total N, and Secchi disk transparency made in Wintergreen Lake. Our procedure showed that waterfowl caused low water quality in Wintergreen Lake.

Stochastic dynamics of small ensembles of non-processive molecular motors: The parallel cluster model

DOE Office of Scientific and Technical Information (OSTI.GOV)

Erdmann, Thorsten; Albert, Philipp J.; Schwarz, Ulrich S.

2013-11-07

Non-processive molecular motors have to work together in ensembles in order to generate appreciable levels of force or movement. In skeletal muscle, for example, hundreds of myosin II molecules cooperate in thick filaments. In non-muscle cells, by contrast, small groups with few tens of non-muscle myosin II motors contribute to essential cellular processes such as transport, shape changes, or mechanosensing. Here we introduce a detailed and analytically tractable model for this important situation. Using a three-state crossbridge model for the myosin II motor cycle and exploiting the assumptions of fast power stroke kinetics and equal load sharing between motors inmore » equivalent states, we reduce the stochastic reaction network to a one-step master equation for the binding and unbinding dynamics (parallel cluster model) and derive the rules for ensemble movement. We find that for constant external load, ensemble dynamics is strongly shaped by the catch bond character of myosin II, which leads to an increase of the fraction of bound motors under load and thus to firm attachment even for small ensembles. This adaptation to load results in a concave force-velocity relation described by a Hill relation. For external load provided by a linear spring, myosin II ensembles dynamically adjust themselves towards an isometric state with constant average position and load. The dynamics of the ensembles is now determined mainly by the distribution of motors over the different kinds of bound states. For increasing stiffness of the external spring, there is a sharp transition beyond which myosin II can no longer perform the power stroke. Slow unbinding from the pre-power-stroke state protects the ensembles against detachment.« less

Misfit of Three Different Implant-Abutment Connections Before and After Cyclic Load Application: An In Vitro Study.

PubMed

Gehrke, Sergio Alexandre; Delgado-Ruiz, Rafael Arcesio; Prados Frutos, Juan Carlos; Prados-Privado, María; Dedavid, Berenice Anina; Granero Marín, Jose Manuel; Calvo Guirado, José Luiz

This study aimed to evaluate the misfit of three different implant-abutment connections before and after cycling load. One hundred twenty dental implants and correspondent prefabricated titanium abutments were used. Three different implant-abutment connections were evaluated: Morse taper (MT group), external hexagon (EH group), and internal hexagon (IH group). Forty implants and 40 abutments were used per group. The parameters for the mechanical evaluation were set as: 360,000 cycles, load of 150 N, and frequency of 4 Hz. Samples were sectioned in their longitudinal and transversal axes, and the misfit of the implant-abutment connection was evaluated by scanning electron microscopy analysis. One-way analyses of variance, Tukey post hoc analyses (α = .05), and t test (P < .05) were used to determine differences between groups. At the longitudinal direction, all the groups showed the presence of microgaps before cycling load; after cycling load, microgaps were reduced in all groups (P > .05). Transversally, only the MT group showed full fitting after cycling load compared with the other groups (EH and IH) (P < .0001). The application of cycling load produces an accommodation of the implant-abutment connection in internal, external, and Morse taper connections. In the longitudinal direction, the accommodation decreases and/or eliminates the gap observed initially (before load). In the horizontal direction, Morse cone implant-abutment connections experience a complete accommodation with the elimination of the gap.

Knotless anchors with sutures external to the anchor body may be at risk for suture cutting through osteopenic bone

PubMed Central

Ono, Y.; Woodmass, J. M.; Nelson, A. A.; Boorman, R. S.; Thornton, G. M.

2016-01-01

Objectives This study evaluated the mechanical performance, under low-load cyclic loading, of two different knotless suture anchor designs: sutures completely internal to the anchor body (SpeedScrew) and sutures external to the anchor body and adjacent to bone (MultiFIX P). Methods Using standard suture loops pulled in-line with the rotator cuff (approximately 60°), anchors were tested in cadaveric bone and foam blocks representing normal to osteopenic bone. Mechanical testing included preloading to 10 N and cyclic loading for 500 cycles from 10 N to 60 N at 60 mm/min. The parameters evaluated were initial displacement, cyclic displacement and number of cycles and load at 3 mm displacement relative to preload. Video recording throughout testing documented the predominant source of suture displacement and the distance of ‘suture cutting through bone’. Results In cadaveric bone and foam blocks, MultiFIX P anchors had significantly greater initial displacement, and lower number of cycles and lower load at 3 mm displacement than SpeedScrew anchors. Video analysis revealed ‘suture cutting through bone’ as the predominant source of suture displacement in cadaveric bone (qualitative) and greater ‘suture cutting through bone’ comparing MultiFIX P with SpeedScrew anchors in foam blocks (quantitative). The greater suture displacement in MultiFIX P anchors was predominantly from suture cutting through bone, which was enhanced in an osteopenic bone model. Conclusions Anchors with sutures external to the anchor body are at risk for suture cutting through bone since the suture eyelet is at the distal tip of the implant and the suture directly abrades against the bone edge during cyclic loading. Suture cutting through bone may be a significant source of fixation failure, particularly in osteopenic bone. Cite this article: Y. Ono, J. M. Woodmass, A. A. Nelson, R. S. Boorman, G. M. Thornton, I. K. Y. Lo. Knotless anchors with sutures external to the anchor body may be at risk for suture cutting through osteopenic bone. Bone Joint Res 2016;5:269–275. DOI: 10.1302/2046-3758.56.2000535. PMID:27357383

Knotless anchors with sutures external to the anchor body may be at risk for suture cutting through osteopenic bone.

PubMed

Ono, Y; Woodmass, J M; Nelson, A A; Boorman, R S; Thornton, G M; Lo, I K Y

2016-06-01

This study evaluated the mechanical performance, under low-load cyclic loading, of two different knotless suture anchor designs: sutures completely internal to the anchor body (SpeedScrew) and sutures external to the anchor body and adjacent to bone (MultiFIX P). Using standard suture loops pulled in-line with the rotator cuff (approximately 60°), anchors were tested in cadaveric bone and foam blocks representing normal to osteopenic bone. Mechanical testing included preloading to 10 N and cyclic loading for 500 cycles from 10 N to 60 N at 60 mm/min. The parameters evaluated were initial displacement, cyclic displacement and number of cycles and load at 3 mm displacement relative to preload. Video recording throughout testing documented the predominant source of suture displacement and the distance of 'suture cutting through bone'. In cadaveric bone and foam blocks, MultiFIX P anchors had significantly greater initial displacement, and lower number of cycles and lower load at 3 mm displacement than SpeedScrew anchors. Video analysis revealed 'suture cutting through bone' as the predominant source of suture displacement in cadaveric bone (qualitative) and greater 'suture cutting through bone' comparing MultiFIX P with SpeedScrew anchors in foam blocks (quantitative). The greater suture displacement in MultiFIX P anchors was predominantly from suture cutting through bone, which was enhanced in an osteopenic bone model. Anchors with sutures external to the anchor body are at risk for suture cutting through bone since the suture eyelet is at the distal tip of the implant and the suture directly abrades against the bone edge during cyclic loading. Suture cutting through bone may be a significant source of fixation failure, particularly in osteopenic bone.Cite this article: Y. Ono, J. M. Woodmass, A. A. Nelson, R. S. Boorman, G. M. Thornton, I. K. Y. Lo. Knotless anchors with sutures external to the anchor body may be at risk for suture cutting through osteopenic bone. Bone Joint Res 2016;5:269-275. DOI: 10.1302/2046-3758.56.2000535. © 2016 Lo et al.

Influence of Wall Porosity and Surfaces Roughness on the Steady Performance of an Externally Pressurized Hydrostatic Conical Bearing Lubricated by a Rabinowitsch Fluid

NASA Astrophysics Data System (ADS)

Walicka, A.; Walicki, E.; Jurczak, P.; Falicki, J.

2017-08-01

In the paper, the influence of both the bearing surfaces roughness as well as porosity of one bearing surface on the pressure distribution and load-carrying capacity of a curvilinear, externally pressurized, thrust bearing is discussed. The equations of motion of a pseudo-plastic Rabinowitsch fluid are used to derive the Reynolds equation. After general considerations on the flow in a bearing clearance and in a porous layer using the Morgan-Cameron approximation and Christensen theory of hydrodynamic lubrication with rough bearing surfaces the modified Reynolds equation is obtained. The analytical solution is presented; as a result one obtains the formulae expressing the pressure distribution and load-carrying capacity. Thrust radial and conical bearings, externally pressurized, are considered as numerical examples.

Evaluation of stability of interface between CCM (Co-Cr-Mo) UCLA abutment and external hex implant

PubMed Central

Yoon, Ki-Joon; Park, Young-Bum; Choi, Hyunmin; Cho, Youngsung; Lee, Jae-Hoon

2016-01-01

PURPOSE The purpose of this study is to evaluate the stability of interface between Co-Cr-Mo (CCM) UCLA abutment and external hex implant. MATERIALS AND METHODS Sixteen external hex implant fixtures were assigned to two groups (CCM and Gold group) and were embedded in molds using clear acrylic resin. Screw-retained prostheses were constructed using CCM UCLA abutment and Gold UCLA abutment. The external implant fixture and screw-retained prostheses were connected using abutment screws. After the abutments were tightened to 30 Ncm torque, 5 kg thermocyclic functional loading was applied by chewing simulator. A target of 1.0 × 106 cycles was applied. After cyclic loading, removal torque values were recorded using a driving torque tester, and the interface between implant fixture and abutment was evaluated by scanning electronic microscope (SEM). The means and standard deviations (SD) between the CCM and Gold groups were analyzed with independent t-test at the significance level of 0.05. RESULTS Fractures of crowns, abutments, abutment screws, and fixtures and loosening of abutment screws were not observed after thermocyclic loading. There were no statistically significant differences at the recorded removal torque values between CCM and Gold groups (P>.05). SEM analysis revealed that remarkable wear patterns were observed at the abutment interface only for Gold UCLA abutments. Those patterns were not observed for other specimens. CONCLUSION Within the limit of this study, CCM UCLA abutment has no statistically significant difference in the stability of interface with external hex implant, compared with Gold UCLA abutment. PMID:28018564

Differentiated perceptions of exertion and energy cost of young women while carrying loads.

PubMed

Robertson, R J; Caspersen, C J; Allison, T G; Skrinar, G S; Abbott, R A; Metz, K F

1982-01-01

Differentiated local ratings of perceived exertion from the legs and central ratings from the chest, and oxygen consumption, were determined during load carriage in seven young women. Subjects walked for 6 min at 3.22, 4.83, 6.44, or 8.05 km X h-1 carrying (1) no load, (2) a load equal to 7.5% of body weight (mean: 4.66 kg) or (3) a load equal to 15% of body weight (mean: 9.32 kg). Thus, each subject underwent 12 separate tests. The external loads were in the form of lead pellets carried in a plastic scuba belt worn around the waist. A differentiation threshold was found at 6.44 km X h-1 for the 0% and 7.5% loads and at 4.83 km X h-1 for the 15% load. At speeds below the threshold, the perception of exertion was similar in the legs, chest and overall. At higher speeds, exertion was perceived to be more intense in the legs than overall and less intense in the chest than overall, suggesting that the local legs signal was the dominant factor in shaping the overall sensation of exertion. The oxygen uptake was greater for the 15% load than for either the 0% or 7.5% loads, but was similar for the 0% and 7.5% loads. Findings suggested a critical weight limit for external loads that could be transported without increasing the metabolic cost beyond that required to move the body weight alone. This limit fell between 7.5% and 15% of the body weight. When oxygen uptake was expressed per kg of total weight transported, there was no loss of metabolic efficiency while carrying loads up to 15% of the body weight.

29 CFR 1910.181 - Derricks.

Code of Federal Regulations, 2010 CFR

2010-07-01

..., working means the external load, in pounds, applied to the derrick, including the weight of load attaching... securely affixed where it is visible to personnel responsible for the safe operation of the equipment. The... of service, and environment, or as specifically indicated below. These inspections shall include the...

Development and validation of a piloted simulation of a helicopter and external sling load

NASA Technical Reports Server (NTRS)

Shaughnessy, J. D.; Deaux, T. N.; Yenni, K. R.

1979-01-01

A generalized, real time, piloted, visual simulation of a single rotor helicopter, suspension system, and external load is described and validated for the full flight envelope of the U.S. Army CH-54 helicopter and cargo container as an example. The mathematical model described uses modified nonlinear classical rotor theory for both the main rotor and tail rotor, nonlinear fuselage aerodynamics, an elastic suspension system, nonlinear load aerodynamics, and a loadground contact model. The implementation of the mathematical model on a large digital computing system is described, and validation of the simulation is discussed. The mathematical model is validated by comparing measured flight data with simulated data, by comparing linearized system matrices, eigenvalues, and eigenvectors with manufacturers' data, and by the subjective comparison of handling characteristics by experienced pilots. A visual landing display system for use in simulation which generates the pilot's forward looking real world display was examined and a special head up, down looking load/landing zone display is described.

Superelastic stress-strain behavior in ferrogels with different types of magneto-elastic coupling

NASA Astrophysics Data System (ADS)

Cremer, Peet; Löwen, Hartmut; Menzel, Andreas M.

Colloidal magnetic particles embedded in an elastic polymer matrix constitute a smart material called ferrogel. It responds to an applied external magnetic field by changes in elastic properties, which can be exploited for various applications like dampers, vibration absorbers, or actuators. Under appropriate conditions, the stress-strain behavior of a ferrogel can display a fascinating feature: superelasticity, the capability to reversibly deform by a huge amount while barely altering the applied load. In a previous work, using numerical simulations, we investigated this behavior assuming that the magnetic moments carried by the embedded particles can freely reorient to minimize their magnetic interaction energy. Here, we extend the analysis to ferrogels where restoring torques by the surrounding matrix hinder rotations towards a magnetically favored configuration. For example, the particles can be chemically cross-linked into the polymer matrix and the magnetic moments can be fixed to the particle axes. We demonstrate that these systems still feature a superelastic regime. As before, the nonlinear stress-strain behavior can be reversibly tailored during operation by external magnetic fields. Yet, the different coupling of the magnetic moments causes different types of response to external stimuli. For instance, an external magnetic field applied parallel to the stretching axis hardly affects the superelastic regime but stiffens the system beyond it. Other smart materials featuring superelasticity, e.g. metallic shape-memory alloys, have already found widespread applications. Our soft polymer systems offer many additional advantages like a typically higher deformability and enhanced biocompatibility combined with high tunability.

Global Response of the Space Shuttle External Tank with the Presence of Intertank Stringer Cracks and Radius Blocks

NASA Technical Reports Server (NTRS)

Lovejoy, Andrew E.; Rankin, Charles C.

2013-01-01

After propellant was loaded into the external tank (ET), the November 5, 2010 launch of Space Shuttle mission STS-133 was scrubbed due to a gaseous hydrogen leak located in a vent line near the ground umbilical and ET connection. Subsequent visual inspections identified cracks in the sprayed-on foam insulation in the forward end of the ET intertank segment, adjacent to the liquid oxygen (LOX) tank, as shown in Figure 1. These cracks necessitated repair of the foam due to debris concerns that violated launch constraints. As part of the repair process, the affected foam was removed to reveal cracks in the underlying external hat stiffeners on the intertank, as shown in Figure 2. Ultimately, five stiffeners were discovered to be cracked adjacent to the LOX tank. As the managing center for the ET Project, NASA Marshall Space Flight Center (MSFC) coordinated failure investigation and repair activities among multiple organizations, which included the ET prime contractor (Lockheed Martin Space Systems Michoud Operations), the Space Shuttle Program Office at the NASA Johnson Space Center (JSC), the NASA Kennedy Space Center (KSC), and the NASA Engineering and Safety Center (NESC). STS-133 utilized the external tank designated as ET-137. Many aspects of the investigation have been reported previously in Refs. 1-7, which focus on the root cause of the failures, the flight readiness rationale and the local analyses of the stringer failures and repair. This paper summarizes the global analyses that were conducted on ET-137 as part of the NESC effort during the investigation, which was conducted primarily to determine if the repairs that were introduced to the stringers would alter the global response of the ET. In the process of the investigation, a new STAGS tabular input capability was developed to more easily introduce the aerodynamic pressure loads using a method that could easily be extended to incorporate finite element property data such as skin and stiffener thicknesses and beam cross-sectional properties.

Characteristics of the internal and external sources of the Mediterranean synoptic cyclones for the period 1956-2013

NASA Astrophysics Data System (ADS)

Almazroui, Mansour; Awad, Adel M.; Nazrul Islam, M.

2017-07-01

This paper investigates the main sources and features of the Mediterranean synoptic cyclones affecting the basin, using the cyclone tracks. The cyclones' tracks are identified using sea level pressure (SLP) from the NCEP/NCAR reanalysis data for the period 1956-2013. The identified cyclones are classified into two categories: basin affected and basin non-affected. Most of the basin-affected (non-affected) cyclones are internal (external), i.e., generated inside (outside) the Mediterranean basin. This study reveals four (five) main sources of internal (external) cyclones. These four (five) main sources generated about 63.76% (57.25%) of the internal (external) cyclones. Seasonal analysis shows that most of the basin-affected internal (external) cyclones were generated in the winter (spring) season. The lowest number of cyclones were found in the summer. Moreover, the synoptic study of the atmospheric systems accompanied the highest- and lowest-generated years demonstrates that the deepening of the north Europe cyclones and the relative positions of Azores- and Siberian-high systems represent the important factors that influence the number of internal cyclones. Essential factors influencing the external cyclones are the strength of the maximum upper wind, Azores high, Siberian high, and orientations of their ridges.

Effect of increased crown height on stress distribution in short dental implant components and their surrounding bone: A finite element analysis.

PubMed

Bulaqi, Haddad Arabi; Mousavi Mashhadi, Mahmoud; Safari, Hamed; Samandari, Mohammad Mahdi; Geramipanah, Farideh

2015-06-01

Implants in posterior regions of the jaw require short dental implants with long crown heights, leading to increased crown-to-implant ratios and mechanical stress. This can lead to fracture and screw loosening. The purpose of this study was to investigate the dynamic nature and behavior of prosthetic components and preimplant bone and evaluate the effect of increased crown height space (CHS) and crown-to-implant ratio on stress concentrations under external oblique forces. The severely resorbed bone of a posterior mandible site was modeled with Mimics and Catia software. A second mandibular premolar tooth was modeled with CHS values of 8.8, 11.2, 13.6, and 16 mm. A Straumann implant (4.1×8 mm), a directly attached crown, and an abutment screw were modeled with geometric data and designed by using SolidWorks software. Abaqus software was used for the dynamic simulation of screw tightening and the application of an external load to the buccal cusp at a 75.8-degree angle with the occlusal plane. The distribution of screw load and member load at each step was compared, and the stress values were calculated within the dental implant complex and surrounding bone. During tightening, the magnitude and distribution of the preload and clamp load were uniform and equal at the cross section of all CHSs. Under an external load, the screw load decreased and member load increased. An increase in the CHS caused the corresponding distribution to become more nonuniform and increased the maximum compressive and tensile stresses in the preimplant bone. Additionally, the von Mises stress decreased at the abutment screw and increased at the abutment and fixture. Under nonaxial forces, increased CHS does not influence the decrease in screw load or increase in member load. However, it contributes to screw loosening and fatigue fracture by skewing the stress distribution to the transverse section of the implant. Copyright © 2015 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.

External Coulomb-Friction Damping For Hydrostatic Bearings

NASA Technical Reports Server (NTRS)

Buckmann, Paul S.

1992-01-01

External friction device damps vibrations of shaft and hydrostatic ring bearing in which it turns. Does not rely on wear-prone facing surfaces. Hydrostatic bearing ring clamped in radially flexing support by side plates clamped against radial surfaces by spring-loaded bolts. Plates provide friction against radial motions of shaft.

External and Internal Factors Influencing Happiness in Elite Collegiate Athletes

ERIC Educational Resources Information Center

Denny, Katherine G.; Steiner, Hans

2009-01-01

When under conditions of high demand and allostatic load, are happiness and satisfaction in four domains (family, friends, academics, recreation) influenced more by external or internal factors? Do student-athletes who lead exceedingly complicated lives report happiness as a function of athletic achievement or internal disposition? Stanford…

Dynamic assessment of reinforced concrete beams repaired with externally bonded FRP sheets

NASA Astrophysics Data System (ADS)

Bonfiglioli, B.; Pascale, G.

2006-01-01

This research deals with RC beams strengthened with FRP. An experimental research is presented which is aimed at evaluating the capability of an experimental modal analysis to assess the stiffness decrease due to damage, as well as the stiffness recovery due to strengthening. Ten beams were tested. All of them were subjected to loading cycles with increasing load levels in order to induce cracking of different severity in them. The beams were then retrofitted by externally bonded FRP sheets. Three types of composites were used. The number of layers was varied, too. Modal tests were carried out after each loading-unloading cycle. The modal frequencies and damping ratios were determined for the first four vibration modes. The results obtained indicate that an experimental modal analysis can give useful information on the severity of damage and the effectiveness of strengthening.

Finite-element computer program for axisymmetric loading situations where components may have a relative interference fit

NASA Technical Reports Server (NTRS)

Taylor, C. M.

1977-01-01

A finite element computer program which enables the analysis of distortions and stresses occurring in compounds having a relative interference is presented. The program is limited to situations in which the loading is axisymmetric. Loads arising from the interference fit(s) and external, inertial, and thermal loadings are accommodated. The components comprise several different homogeneous isotropic materials whose properties may be a function of temperature. An example illustrating the data input and program output is given.

Synthesis of polyoxometalate-loaded epoxy composites

DOEpatents

Anderson, Benjamin J

2014-10-07

The synthesis of a polyoxometalate-loaded epoxy uses a one-step cure by applying an external stimulus to release the acid from the polyoxometalate and thereby catalyze the cure reaction of the epoxy resin. Such polyoxometalate-loaded epoxy composites afford the cured epoxy unique properties imparted by the intrinsic properties of the polyoxometalate. For example, polyoxometalate-loaded epoxy composites can be used as corrosion resistant epoxy coatings, for encapsulation of electronics with improved dielectric properties, and for structural applications with improved mechanical properties.

Effect of Physical Load on Aerobic Exercise Performance during Heat Stress.

PubMed

Kenefick, Robert W; Heavens, Kristen R; Luippold, Adam J; Charkoudian, Nisha; Schwartz, Steven A; Cheuvront, Samuel N

2017-12-01

This study aimed to investigate the effect of increasing external loads on 5-km treadmill time trial (TT) performance in 20°C and 40°C environmental conditions and to construct an ecologically relevant performance prediction decision aid. Twenty-six male and four female volunteers (age, 23.5 ± 6.9 yr; weight, 76.0 ± 8.9 kg; height, 1.75 ± 0.07 m; V˙O2peak, 50.7 ± 4.5 mL·kg·min) participated in a counterbalanced, mixed-model design, with each subject assigned to a load group (20%, 30%, or 50% body mass (BM); n = 10 per group). Volunteers performed three, self-paced 5-km familiarization TT (treadmill) without external load. Each volunteer then performed a 5-km TT in each environment with loads of either 20% (n = 10), 30% (n = 10), or 50% (n = 10) of BM. 1) Loads of (20%, 30%, and 50% of BM) impaired 5-km TT performance compared with that when unloaded (P < 0.05); 2) the time penalties of the 20% and 30% load were <50% load (P < 0.05); 3) in all trials, the addition of heat exposure reduced 5-km TT performance beyond the penalty of load itself (P < 0.05); and 4) the combination of heat and 50% load resulted in a substantial penalty such that continuous work was not sustainable for all of the volunteers. Relative to prediction models using fixed or constant workload exercise trials, an ecologically valid decision aid was developed from self-paced data, in which pace (km·h) can be predicted for individual levels of heat, load, or heat + load in combination.

14 CFR 133.37 - Crewmember training, currency, and testing requirements.

Code of Federal Regulations, 2010 CFR

2010-01-01

... requirements. 133.37 Section 133.37 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... ROTORCRAFT EXTERNAL-LOAD OPERATIONS Operating Rules and Related Requirements § 133.37 Crewmember training... Administrator knowledge and skill with respect to the rotorcraft-load combination in accordance with § 133.23...

Macro- and meiofaunal community features in the critical environmental system of a tourist harbour (Rapallo, Ligurian Sea, NW Mediterranean).

PubMed

Harriague, Anabella Covazzi; Albertelli, Giancarlo; Misic, Cristina

2012-03-01

Two samplings were carried out in a tourist harbour, during low and high touristic activity periods, to study the macro- and meiofaunal communities in relation to the environmental features. A multivariate analysis showed close relationships: the maritime traffic disturbance and the food quality and availability drive the spatial differences of the assemblages, dividing the area into three sub-areas: the area near the Boate torrent that empties into the harbour, the harbour proper, and the external area (just outside the harbour). Macro- and meiofauna showed notably different temporal trends, indicating competition for the resources and the higher sensitivity of the macrofauna to environmental pressures. The macrofauna strongly decreased as a response to heavier harbour activities, with increasing turbidity also affecting the external station outside the harbour. Finally, comparing the macrofaunal communities to those sampled in the same area 10 years before, we found that their abundance, richness and biomass had notably decreased, highlighting the worsening of the harbour environment due to the increased organic load and turbidity. Copyright © 2011 Elsevier Ltd. All rights reserved.

Electromechanical millimotor

DOEpatents

Garcia, E.J.; Christenson, T.R.; Polosky, M.A.

1999-06-29

A millimeter-sized machine, including electromagnetic circuits adapted to convert electromagnetic energy to mechanical energy, for engaging and operating external mechanical loads. A plurality of millimeter-sized magnetic actuators operate out of phase with each other to control a plurality of millimeter-sized structural elements to drive an external mechanical load. Each actuator is connected to a link. Each link, in turn, is connected to a drive pinion at another similar pivoting joint. When the magnetic actuators are energized, each drive pinion is then capable of driving a larger output gear in gear-like fashion to produce positive torque about the drive pinion center at all angular positions of the output gear. 29 figs.

Grid oscillators

NASA Technical Reports Server (NTRS)

Popovic, Zorana B.; Kim, Moonil; Rutledge, David B.

1988-01-01

Loading a two-dimensional grid with active devices offers a means of combining the power of solid-state oscillators in the microwave and millimeter-wave range. The grid structure allows a large number of negative resistance devices to be combined. This approach is attractive because the active devices do not require an external locking signal, and the combining is done in free space. In addition, the loaded grid is a planar structure amenable to monolithic integration. Measurements on a 25-MESFET grid at 9.7 GHz show power-combining and frequency-locking without an external locking signal, with an ERP of 37 W. Experimental far-field patterns agree with theoretical results obtained using reciprocity.

Electromechanical millimotor

DOEpatents

Garcia, Ernest J.; Christenson, Todd R.; Polosky, Marc A.

1999-01-01

A millimeter-sized machine, including electromagnetic circuits adapted to convert electromagnetic energy to mechanical energy, for engaging and operating external mechanical loads. A plurality of millimeter-sized magnetic actuators operate out of phase with each other to control a plurality of millimeter-sized structural elements to drive an external mechanical load. Each actuator is connected to a link. Each link, in turn, is connected to a drive pinion at another similar pivoting joint. When the magnetic actuators are energized, each drive pinion is then capable of driving a larger output gear in gear-like fashion to produce positive torque about the drive pinion center at all angular positions of the output gear.

Results of experimental tests in the MSFC 14 x 14 inch trisonic wind tunnel on a .004 scale model space shuttle integrated vehicle 5 (model 77-O, 74-TS) to relieve wing loads during ascent (IA71)

NASA Technical Reports Server (NTRS)

Allen, E. C.

1975-01-01

Results are presented for the 0.004-scale orbiter, external tank, and solid rocket boosters combined as an integrated vehicle in a trisonic wind tunnel at mach numbers from 0.6 to 2.0. The primary test objective was to determine the effectiveness of several methods in relieving the Orbiter wing bending and torsion loads and moments during launch. Effects of several midwing spoilers, termed flipper doors, and Orbiter/external tank incidence were investigated. Photographs are included.

Rotating electric machine with fluid supported parts

DOEpatents

Smith, Jr., Joseph L.; Kirtley, Jr., James L.

1981-01-01

A rotating electric machine in which the armature winding thereof and other parts are supported by a liquid to withstand the mechanical stresses applied during transient overloads and the like. In particular, a narrow gap is provided between the armature winding and the stator which supports it and this gap is filled with an externally pressurized viscous liquid. The liquid is externally pressurized sufficiently to balance the static loads on the armature winding. Transient mechanical loads which deform the armature winding alter the gap dimensions and thereby additionally pressurize the viscous liquid to oppose the armature winding deformation and more nearly uniformly to distribute the resulting mechanical stresses.

The creation of racks and nanopores creation in various allotropes of boron due to the mechanical loads

NASA Astrophysics Data System (ADS)

Sadeghzadeh, S.

2017-11-01

Two-dimensional (2D) materials have recently attracted a great attraction. This paper provides a detailed discussion on the rupture mechanisms of different allotropes of boron. As a new 2D material by using a reactive molecular dynamics model, probable types of rupture for borophene sheets were studied, among which two dominant mechanisms were observed: creation of the cracks and formation of nanopores. The results obtained are compared to those for graphene and h-BN nano sheets, although the rupture mechanism was completely different from the graphene and h-BN sheets. The simulations suggested that borophene might remain more stable against external mechanical loads than graphene and BN sheets. Cracking leads to larger strain along the loading direction, whereas the creation of local pores spends the imposed energy for breaking the internal bonds and so flowing the external energy into the various bonds increases the number of pores. For the armchair-types, cracking is a dominant mechanism while for the zigzag-type the common mechanism is the creation of nanopores. These interesting results may help to design a new class of semiconductors that remain stable even when are sustaining uncontrollable external stresses.

Response of Submerged Macrophyte Communities to External and Internal Restoration Measures in North Temperate Shallow Lakes

PubMed Central

Hilt, Sabine; Alirangues Nuñez, Marta M.; Bakker, Elisabeth S.; Blindow, Irmgard; Davidson, Thomas A.; Gillefalk, Mikael; Hansson, Lars-Anders; Janse, Jan H.; Janssen, Annette B. G.; Jeppesen, Erik; Kabus, Timm; Kelly, Andrea; Köhler, Jan; Lauridsen, Torben L.; Mooij, Wolf M.; Noordhuis, Ruurd; Phillips, Geoff; Rücker, Jacqueline; Schuster, Hans-Heinrich; Søndergaard, Martin; Teurlincx, Sven; van de Weyer, Klaus; van Donk, Ellen; Waterstraat, Arno; Willby, Nigel; Sayer, Carl D.

2018-01-01

Submerged macrophytes play a key role in north temperate shallow lakes by stabilizing clear-water conditions. Eutrophication has resulted in macrophyte loss and shifts to turbid conditions in many lakes. Considerable efforts have been devoted to shallow lake restoration in many countries, but long-term success depends on a stable recovery of submerged macrophytes. However, recovery patterns vary widely and remain to be fully understood. We hypothesize that reduced external nutrient loading leads to an intermediate recovery state with clear spring and turbid summer conditions similar to the pattern described for eutrophication. In contrast, lake internal restoration measures can result in transient clear-water conditions both in spring and summer and reversals to turbid conditions. Furthermore, we hypothesize that these contrasting restoration measures result in different macrophyte species composition, with added implications for seasonal dynamics due to differences in plant traits. To test these hypotheses, we analyzed data on water quality and submerged macrophytes from 49 north temperate shallow lakes that were in a turbid state and subjected to restoration measures. To study the dynamics of macrophytes during nutrient load reduction, we adapted the ecosystem model PCLake. Our survey and model simulations revealed the existence of an intermediate recovery state upon reduced external nutrient loading, characterized by spring clear-water phases and turbid summers, whereas internal lake restoration measures often resulted in clear-water conditions in spring and summer with returns to turbid conditions after some years. External and internal lake restoration measures resulted in different macrophyte communities. The intermediate recovery state following reduced nutrient loading is characterized by a few macrophyte species (mainly pondweeds) that can resist wave action allowing survival in shallow areas, germinate early in spring, have energy-rich vegetative propagules facilitating rapid initial growth and that can complete their life cycle by early summer. Later in the growing season these plants are, according to our simulations, outcompeted by periphyton, leading to late-summer phytoplankton blooms. Internal lake restoration measures often coincide with a rapid but transient colonization by hornworts, waterweeds or charophytes. Stable clear-water conditions and a diverse macrophyte flora only occurred decades after external nutrient load reduction or when measures were combined. PMID:29515607

Climate Variability Impacts on Watershed Nutrient Delivery and Reservoir Production

NASA Astrophysics Data System (ADS)

White, J. D.; Prochnow, S. J.; Zygo, L. M.; Byars, B. W.

2005-05-01

Reservoirs in agricultural dominated watersheds tend to exhibit pulse-system behavior especially if located in climates dominated by summer convective precipitation inputs. Concentration and bulk mass of nutrient and sediment inputs into reservoir systems vary in terms of timing and magnitude of delivery from watershed sources to reservoirs under these climate conditions. Reservoir management often focuses on long-term average inputs without considering short and long-term impacts of variation in loading. In this study we modeled a watershed-reservoir system to assess how climate variability affects reservoir primary production through shifts in external loading and internal recycling of limiting nutrients. The Bosque watershed encompasses 423,824 ha in central Texas which delivers water to Lake Waco, a 2900 ha reservoir that is the primary water source for the city of Waco and surrounding areas. Utilizing the Soil Water Assessment Tool for the watershed and river simulations and the CE-Qual-2e model for the reservoir, hydrologic and nutrient dynamics were simulated for a 10 year period encompassing two ENSO cycles. The models were calibrated based on point measurement of water quality attributes for a two year time period. Results indicated that watershed delivery of nutrients was affected by the presence and density of small flood-control structure in the watershed. However, considerable nitrogen and phosphorus loadings were derived from soils in the upper watershed which have had long-term waste-application from concentrated animal feeding operations. During El Niño years, nutrient and sediment loads increased by 3 times above non-El Niño years. The simulated response within the reservoir to these nutrient and sediment loads had both direct and indirect. Productivity evaluated from chlorophyll a and algal biomass increased under El Niño conditions, however species composition shifts were found with an increase in cyanobacteria dominance. In non-El Niño years, species composition was more evenly distributed. At the longer time scale, El Niño events with accompanying increase in nutrient loads were followed by years in which productivity declined below levels predicted solely by nutrient ratios. This was due to subtle shifts in organic matter decomposition where productive years are followed by increases in refractory material which sequesters nutrients and reduces internal loading.

A simple method for assessment of muscle force, velocity, and power producing capacities from functional movement tasks.

PubMed

Zivkovic, Milena Z; Djuric, Sasa; Cuk, Ivan; Suzovic, Dejan; Jaric, Slobodan

2017-07-01

A range of force (F) and velocity (V) data obtained from functional movement tasks (e.g., running, jumping, throwing, lifting, cycling) performed under variety of external loads have typically revealed strong and approximately linear F-V relationships. The regression model parameters reveal the maximum F (F-intercept), V (V-intercept), and power (P) producing capacities of the tested muscles. The aim of the present study was to evaluate the level of agreement between the routinely used "multiple-load model" and a simple "two-load model" based on direct assessment of the F-V relationship from only 2 external loads applied. Twelve participants were tested on the maximum performance vertical jumps, cycling, bench press throws, and bench pull performed against a variety of different loads. All 4 tested tasks revealed both exceptionally strong relationships between the parameters of the 2 models (median R = 0.98) and a lack of meaningful differences between their magnitudes (fixed bias below 3.4%). Therefore, addition of another load to the standard tests of various functional tasks typically conducted under a single set of mechanical conditions could allow for the assessment of the muscle mechanical properties such as the muscle F, V, and P producing capacities.

The dopamine receptor D4 gene and familial loading interact with perceived parenting in predicting externalizing behavior problems in early adolescence: the TRacking Adolescents' Individual Lives Survey (TRAILS).

PubMed

Marsman, Rianne; Oldehinkel, Albertine J; Ormel, Johan; Buitelaar, Jan K

2013-08-30

Although externalizing behavior problems show in general a high stability over time, the course of externalizing behavior problems may vary from individual to individual. Our main goal was to investigate the predictive role of parenting on externalizing behavior problems. In addition, we investigated the potential moderating role of gender and genetic risk (operationalized as familial loading of externalizing behavior problems (FLE), and presence or absence of the dopamine receptor D4 (DRD4) 7-repeat and 4-repeat allele, respectively). Perceived parenting (rejection, emotional warmth, and overprotection) and FLE were assessed in a population-based sample of 1768 10- to 12-year-old adolescents. Externalizing behavior problems were assessed at the same age and 212 years later by parent report (CBCL) and self-report (YSR). DNA was extracted from blood samples. Parental emotional warmth predicted lower, and parental overprotection and rejection predicted higher levels of externalizing behavior problems. Whereas none of the parenting factors interacted with gender and the DRD4 7-repeat allele, we did find interaction effects with FLE and the DRD4 4-repeat allele. That is, the predictive effect of parental rejection was only observed in adolescents from low FLE families and the predictive effect of parental overprotection was stronger in adolescents not carrying the DRD4 4-repeat allele. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

Midsole material-related force control during heel-toe running.

PubMed

Kersting, Uwe G; Brüggemann, Gert-Peter

2006-01-01

The impact maximum and rearfoot eversion have been used as indicators of load on internal structures in running. The midsole hardness of a typical running shoe was varied systematically to determine the relationship between external ground reaction force (GRF), in-shoe force, and kinematic variables. Eight subjects were tested during overground running at 4 m/s. Rearfoot movement as well as in-shoe forces and external GRF varied nonsystematically with midsole hardness. Kinematic parameters such as knee flexion and foot velocity at touchdown (TD), also varied nonsystematically with altered midsole hardness. Results demonstrate that considerable variations of in-shoe loading occur that were not depicted by external GRF measurements alone. Individuals apparently use different strategies of mechanical and neuromuscular adaptation in response to footwear modifications. In conclusion, shoe design effects on impact forces or other factors relating to injuries depend on the individual and therefore cannot be generalized.

Biomechanical monitoring of healing bone based on acoustic emission technology.

PubMed

Hirasawa, Yasusuke; Takai, Shinro; Kim, Wook-Cheol; Takenaka, Nobuyuki; Yoshino, Nobuyuki; Watanabe, Yoshinobu

2002-09-01

Acoustic emission testing is a well-established method for assessment of the mechanical integrity of general construction projects. The purpose of the current study was to investigate the usefulness of acoustic emission technology in monitoring the yield strength of healing callus during external fixation. Thirty-five patients with 39 long bones treated with external fixation were evaluated for fracture healing by monitoring load for the initiation of acoustic emission signal (yield strength) under axial loading. The major criteria for functional bone union based on acoustic emission testing were (1) no acoustic emission signal on full weightbearing, and (2) a higher estimated strength than body weight. The yield strength monitored by acoustic emission testing increased with the time of healing. The external fixator could be removed safely and successfully in 97% of the patients. Thus, the acoustic emission method has good potential as a reliable method for monitoring the mechanical status of healing bone.

Spin-oscillator model for the unzipping of biomolecules by mechanical force.

PubMed

Prados, A; Carpio, A; Bonilla, L L

2012-08-01

A spin-oscillator system models unzipping of biomolecules (such as DNA, RNA, or proteins) subject to an external force. The system comprises a macroscopic degree of freedom, represented by a one-dimensional oscillator, and internal degrees of freedom, represented by Glauber spins with nearest-neighbor interaction and a coupling constant proportional to the oscillator position. At a critical value F(c) of an applied external force F, the oscillator rest position (order parameter) changes abruptly and the system undergoes a first-order phase transition. When the external force is cycled at different rates, the extension given by the oscillator position exhibits a hysteresis cycle at high loading rates, whereas it moves reversibly over the equilibrium force-extension curve at very low loading rates. Under constant force, the logarithm of the residence time at the stable and metastable oscillator rest position is proportional to F-F(c) as in an Arrhenius law.

A simple theory of motor protein kinetics and energetics. II.

PubMed

Qian, H

2000-01-10

A three-state stochastic model of motor protein [Qian, Biophys. Chem. 67 (1997) pp. 263-267] is further developed to illustrate the relationship between the external load on an individual motor protein in aqueous solution with various ATP concentrations and its steady-state velocity. A wide variety of dynamic motor behavior are obtained from this simple model. For the particular case of free-load translocation being the most unfavorable step within the hydrolysis cycle, the load-velocity curve is quasi-linear, V/Vmax = (cF/Fmax-c)/(1-c), in contrast to the hyperbolic relationship proposed by A.V. Hill for macroscopic muscle. Significant deviation from the linearity is expected when the velocity is less than 10% of its maximal (free-load) value--a situation under which the processivity of motor diminishes and experimental observations are less certain. We then investigate the dependence of load-velocity curve on ATP (ADP) concentration. It is shown that the free load Vmax exhibits a Michaelis-Menten like behavior, and the isometric Fmax increases linearly with ln([ATP]/[ADP]). However, the quasi-linear region is independent of the ATP concentration, yielding an apparently ATP-independent maximal force below the true isometric force. Finally, the heat production as a function of ATP concentration and external load are calculated. In simple terms and solved with elementary algebra, the present model provides an integrated picture of biochemical kinetics and mechanical energetics of motor proteins.

Laboratory investigation of a novel method to accelerate healing in asphalt mixtures using thermal treatment.

DOT National Transportation Integrated Search

2009-08-01

Asphalt binders have an inherent ability to reverse damage in the form of micro-cracks that is caused : due to the repeated action of external loads. This reversal occurs during rest periods between load : cycles. The phenomenon of crack reversal is ...

A two-dimensional analytical model and experimental validation of garter stitch knitted shape memory alloy actuator architecture

NASA Astrophysics Data System (ADS)

Abel, Julianna; Luntz, Jonathan; Brei, Diann

2012-08-01

Active knits are a unique architectural approach to meeting emerging smart structure needs for distributed high strain actuation with simultaneous force generation. This paper presents an analytical state-based model for predicting the actuation response of a shape memory alloy (SMA) garter knit textile. Garter knits generate significant contraction against moderate to large loads when heated, due to the continuous interlocked network of loops of SMA wire. For this knit architecture, the states of operation are defined on the basis of the thermal and mechanical loading of the textile, the resulting phase change of the SMA, and the load path followed to that state. Transitions between these operational states induce either stick or slip frictional forces depending upon the state and path, which affect the actuation response. A load-extension model of the textile is derived for each operational state using elastica theory and Euler-Bernoulli beam bending for the large deformations within a loop of wire based on the stress-strain behavior of the SMA material. This provides kinematic and kinetic relations which scale to form analytical transcendental expressions for the net actuation motion against an external load. This model was validated experimentally for an SMA garter knit textile over a range of applied forces with good correlation for both the load-extension behavior in each state as well as the net motion produced during the actuation cycle (250% recoverable strain and over 50% actuation). The two-dimensional analytical model of the garter stitch active knit provides the ability to predict the kinetic actuation performance, providing the basis for the design and synthesis of large stroke, large force distributed actuators that employ this novel architecture.

External Quality Assessment for Zika Virus Molecular Diagnostic Testing, Brazil.

PubMed

Fischer, Carlo; Pedroso, Celia; Mendrone, Alfredo; Bispo de Filippis, Ana Maria; Vallinoto, Antonio Carlos Rosário; Ribeiro, Bergmann Morais; Durigon, Edison Luiz; Marques, Ernesto T A; Campos, Gubio S; Viana, Isabelle F T; Levi, José Eduardo; Scarpelli, Luciano Cesar; Nogueira, Mauricio Lacerda; Bastos, Michele de Souza; Souza, Nathalia C Santiago; Khouri, Ricardo; Lira, Sanny; Komninakis, Shirley Vasconcelos; Baronti, Cécile; Charrel, Rémi N; Kümmerer, Beate M; Drosten, Christian; Brites, Carlos; de Lamballerie, Xavier; Niedrig, Matthias; Netto, Eduardo Martins; Drexler, Jan Felix

2018-05-01

We conducted an external quality assessment of Zika virus molecular diagnostic tests in Brazil using a new Zika virus standard. Of 15 laboratories, 73% showed limited sensitivity and specificity. Viral load estimates varied significantly. Continuous quality assurance is needed to adequately estimate risk for Zika virus-associated disease and determine patient care.

KSC-04PD-1270

NASA Technical Reports Server (NTRS)

2004-01-01

KENNEDY SPACE CENTER, FLA. After leaving the Vehicle Assembly Building, the external tank seen here points its way toward the Turn Basin and the Banana River. The tank will be loaded onto the waiting barge and transferred to the Michoud Space Systems Assembly Facility near New Orleans where redesign of the external tank is underway for Return to Flight.

Biomechanical consequences of callus development in Hoffmann, Wagner, Orthofix and Ilizarov external fixators.

PubMed

Juan, J A; Prat, J; Vera, P; Hoyos, J V; Sánchez-Lacuesta, J; Peris, J L; Dejoz, R; Alepuz, R

1992-09-01

A theoretical analysis by a finite elements model (FEM) of some external fixators (Hoffmann, Wagner, Orthofix and Ilizarov) was carried out. This study considered a logarithmic progress of callus elastic characteristics. A standard configuration of each fixator was defined where design and application characteristics were modified. A comparison among standard configurations and influence of every variation was made with regard to displacement and load transmission at the fracture site. An experimental evaluation of standard configurations was performed with a testing machine. After experimental validation of the theoretical model was achieved, an application of physiological loads which act on a fractured limb during normal gait was analysed. A minimal contribution from an external fixator to the total rigidity of the bone-callus-fixator system was assessed when a callus showing minimum elastic characteristics had just been established. Insufficient rigidity from the fixation devices to assure an adequate immobilization during the early stages of fracture healing was verified. However, regardless of the external fixator, callus development was the overriding element for the rigidity of the fixator-bone system.

EEG correlates of finger movements with different inertial load conditions as revealed by averaging techniques.

PubMed

Slobounov, S; Tutwiler, R; Rearick, M; Challis, J H

1999-10-01

The present study was aimed to further address the general empirical question regarding the sensitivity of EEG correlates toward specific kinematic and/or kinetic movement parameters. In particular, we examined whether adding different inertial loads to the index finger, while a subject produced various amplitudes of discrete finger movements, influenced the movement-related potentials (MRP). Our experimental design systematically controlled the angular displacement, velocity and acceleration (kinematic) profiles of finger movement while torque (kinetics) was varied by adding different external loads opposing finger flexion movement. We applied time-domain averaging of EEG single trials in order to extract three movement-related potentials (BP-600 to -500 BP-100 to 0 and N0 to 100) preceding and accompanying 25, 50 and 75 degrees unilateral finger movements with no inertial load, small (100 g) and large (200 g) loading. It was shown that both inertial load and the degree of angular displacement of index finger flexion increased the amplitude of late components of MRP (BP-100 to 0 and N0 to 100) over frontal and precentral areas. In contrast, the external load and movement amplitude manipulations did not influence the earlier component of the MRP (BP- 600 to -500). Overall, the data demonstrate that adding inertial load to the finger with larger angular displacements involves systematic increase in activation across frontal and precentral areas that are related to movement initiation as reflected in BP-100 to 0 and N0 to 100.

A new technique using roentgen stereophotogrammetry to measure changes in the spatial conformation of bovine hind claws in response to external loads.

PubMed

Ouweltjes, W; Gussekloo, S W S; Spoor, C W; van Leeuwen, J L

2016-02-01

Claw and locomotion problems are widespread in ungulates. Although it is presumed that mechanical overload is an important contributor to claw tissue damage and impaired locomotion, deformation and claw injury as a result of mechanical loading has been poorly quantified and, as a result, practical solutions to reduce such lesions have been established mostly through trial and error. In this study, an experimental technique was developed that allowed the measurement under controlled loading regimes of minute deformations in the lower limbs of dissected specimens from large ungulates. Roentgen stereophotogrammetric analysis (RSA) was applied to obtain 3D marker coordinates with an accuracy of up to 0.1 mm with optimal contrast and to determine changes in the spatial conformation. A force plate was used to record the applied forces in three dimensions. The results obtained for a test sample (cattle hind leg) under three loading conditions showed that small load-induced deformations and translations as well as small changes in centres of force application could be measured. Accuracy of the order of 0.2-0.3 mm was feasible under practical circumstances with suboptimal contrast. These quantifications of claw deformation during loading improve understanding of the spatial strain distribution as a result of external loading and the risks of tissue overload. The method promises to be useful in determining load-deformation relationships for a wide variety of specimens and circumstances. Copyright © 2015 Elsevier Ltd. All rights reserved.

Selective Effects of Training Against Weight and Inertia on Muscle Mechanical Properties.

PubMed

Djuric, Sasa; Cuk, Ivan; Sreckovic, Sreten; Mirkov, Dragan; Nedeljkovic, Aleksandar; Jaric, Slobodan

2016-10-01

To explore the effects of training against mechanically different types of loads on muscle force (F), velocity (V), and power (P) outputs. Subjects practiced maximum bench throws over 8 wk against a bar predominantly loaded by approximately constant external force (weight), weight plates (weight plus inertia), or weight plates whose weight was compensated by a constant external force pulling upward (inertia). Instead of a typically applied single trial performed against a selected load, the pretest and posttest consisted of the same task performed against 8 different loads ranging from 30% to 79% of the subject's maximum strength applied by adding weight plates to the bar. That provided a range of F and V data for subsequent modeling by linear F-V regression revealing the maximum F (F-intercept), V (V-intercept), and P (P = FV/4). Although all 3 training conditions resulted in increased P, the inertia type of the training load could be somewhat more effective than weight. An even more important finding was that the P increase could be almost exclusively based on a gain in F, V, or both when weight, inertia, or weight-plus-inertia training load were applied, respectively. The inertia training load is more effective than weight in increasing P and weight and inertia may be applied for selective gains in F and V, respectively, whereas the linear F-V model obtained from loaded trials could be used for discerning among muscle F, V, and P.

Measurement of external forces and torques on a large pointing system

NASA Technical Reports Server (NTRS)

Morenus, R. C.

1980-01-01

Methods of measuring external forces and torques are discussed, in general and as applied to the Large Pointing System wind tunnel tests. The LPS tests were in two phases. The first test was a preliminary test of three models representing coelostat, heliostat, and on-gimbal telescope configurations. The second test explored the coelostat configuration in more detail. The second test used a different setup for measuring external loads. Some results are given from both tests.

Feasibility Study of the Electromagnetic Damper for Cable Structures Using Real-Time Hybrid Simulation

PubMed Central

Jung, Ho-Yeon; Kim, In-Ho; Jung, Hyung-Jo

2017-01-01

Cable structure is a major component of long-span bridges, such as cable-stayed and suspension bridges, and it transfers the main loads of bridges to the pylons. As these cable structures are exposed to continuous external loads, such as vehicle and wind loads, vibration control and continuous monitoring of the cable are required. In this study, an electromagnetic (EM) damper was designed and fabricated for vibration control and monitoring of the cable structure. EM dampers, also called regenerative dampers, consist of permanent magnets and coils. The electromagnetic force due to the relative motion between the coil and the permanent magnet can be used to control the vibration of the structure. The electrical energy can be used as a power source for the monitoring system. The effects of the design parameters of the damper were numerically analyzed and the damper was fabricated. The characteristics of the damper were analyzed with various external load changes. Finally, the vibration-control and energy-harvesting performances of the cable structure were evaluated through a hybrid simulation. The vibration-control and energy-harvesting performances for various loads were analyzed and the applicability to the cable structure of the EM damper was evaluated. PMID:29088077

Feasibility Study of the Electromagnetic Damper for Cable Structures Using Real-Time Hybrid Simulation.

PubMed

Jung, Ho-Yeon; Kim, In-Ho; Jung, Hyung-Jo

2017-10-31

Cable structure is a major component of long-span bridges, such as cable-stayed and suspension bridges, and it transfers the main loads of bridges to the pylons. As these cable structures are exposed to continuous external loads, such as vehicle and wind loads, vibration control and continuous monitoring of the cable are required. In this study, an electromagnetic (EM) damper was designed and fabricated for vibration control and monitoring of the cable structure. EM dampers, also called regenerative dampers, consist of permanent magnets and coils. The electromagnetic force due to the relative motion between the coil and the permanent magnet can be used to control the vibration of the structure. The electrical energy can be used as a power source for the monitoring system. The effects of the design parameters of the damper were numerically analyzed and the damper was fabricated. The characteristics of the damper were analyzed with various external load changes. Finally, the vibration-control and energy-harvesting performances of the cable structure were evaluated through a hybrid simulation. The vibration-control and energy-harvesting performances for various loads were analyzed and the applicability to the cable structure of the EM damper was evaluated.

Development of a finite element based delamination analysis for laminates subject to extension, bending, and torsion

NASA Technical Reports Server (NTRS)

Hooper, Steven J.

1989-01-01

Delamination is a common failure mode of laminated composite materials. This type of failure frequently occurs at the free edges of laminates where singular interlaminar stresses are developed due to the difference in Poisson's ratios between adjacent plies. Typically the delaminations develop between 90 degree plies and adjacent angle plies. Edge delamination has been studied by several investigators using a variety of techniques. Recently, Chan and Ochoa applied the quasi-three-dimensional finite element model to the analysis of a laminate subject to bending, extension, and torsion. This problem is of particular significance relative to the structural integrity of composite helicopter rotors. The task undertaken was to incorporate Chan and Ochoa's formulation into a Raju Q3DG program. The resulting program is capable of modeling extension, bending, and torsional mechanical loadings as well as thermal and hygroscopic loadings. The addition of the torsional and bending loading capability will provide the capability to perform a delamination analysis of a general unsymmetric laminate containing four cracks, each of a different length. The solutions obtained using this program are evaluated by comparing them with solutions from a full three-dimensional finite element solution. This comparison facilitates the assessment of three dimensional affects such as the warping constraint imposed by the load frame grips. It wlso facilitates the evaluation of the external load representation employed in the Q3D formulation. Finally, strain energy release rates computed from the three-dimensional results are compared with those predicted using the quasi-three-dimensional formulation.

Bed Load Variability and Morphology of Gravel Bed Rivers Subject to Unsteady Flow: A Laboratory Investigation

NASA Astrophysics Data System (ADS)

Redolfi, M.; Bertoldi, W.; Tubino, M.; Welber, M.

2018-02-01

Measurement and estimation of bed load transport in gravel bed rivers are highly affected by its temporal fluctuations. Such variability is primarily driven by the flow regime but is also associated with a variety of inherent channel processes, such as flow turbulence, grain entrainment, and bed forms migration. These internal and external controls often act at comparable time scales, and are therefore difficult to disentangle, thus hindering the study of bed load variability under unsteady flow regime. In this paper, we report on laboratory experiments performed in a large, mobile bed flume where typical hydromorphological conditions of gravel bed rivers were reproduced. Data from a large number of replicated runs, including triangular and square-wave hydrographs, were used to build a statistically sound description of sediment transport processes. We found that the inherent variability of bed load flux strongly depends on the sampling interval, and it is significantly higher in complex, wandering or braided channels. This variability can be filtered out by computing the mean response over the experimental replicates, which allows us to highlight two distinctive phenomena: (i) an overshooting (undershooting) response of the mean bed load flux to a sudden increase (decrease) of discharge, and (ii) a clockwise hysteresis in the sediment rating curve. We then provide an interpretation of these findings through a conceptual mathematical model, showing how both phenomena are associated with a lagging morphological adaptation to unsteady flow. Overall, this work provides basic information for evaluating, monitoring, and managing gravel transport in morphologically active rivers.

Increasing Running Step Rate Reduces Patellofemoral Joint Forces

PubMed Central

Lenhart, Rachel L.; Thelen, Darryl G.; Wille, Christa M.; Chumanov, Elizabeth S.; Heiderscheit, Bryan C.

2013-01-01

Purpose Increasing step rate has been shown to elicit changes in joint kinematics and kinetics during running, and has been suggested as a possible rehabilitation strategy for runners with patellofemoral pain. The purpose of this study was to determine how altering step rate affects internal muscle forces and patellofemoral joint loads, and then to determine what kinematic and kinetic factors best predict changes in joint loading. Methods We recorded whole body kinematics of 30 healthy adults running on an instrumented treadmill at three step rate conditions (90%, 100%, and 110% of preferred step rate). We then used a 3D lower extremity musculoskeletal model to estimate muscle, patellar tendon, and patellofemoral joint forces throughout the running gait cycles. Additionally, linear regression analysis allowed us to ascertain the relative influence of limb posture and external loads on patellofemoral joint force. Results Increasing step rate to 110% of preferred reduced peak patellofemoral joint force by 14%. Peak muscle forces were also altered as a result of the increased step rate with hip, knee and ankle extensor forces, and hip abductor forces all reduced in mid-stance. Compared to the 90% step rate condition, there was a concomitant increase in peak rectus femoris and hamstring loads during early and late swing, respectively, at higher step rates. Peak stance phase knee flexion decreased with increasing step rate, and was found to be the most important predictor of the reduction in patellofemoral joint loading. Conclusion Increasing step rate is an effective strategy to reduce patellofemoral joint forces and could be effective in modulating biomechanical factors that can contribute to patellofemoral pain. PMID:23917470

Coupling and Elastic Loading Affect the Active Response by the Inner Ear Hair Cell Bundles

PubMed Central

Strimbu, Clark Elliott; Fredrickson-Hemsing, Lea; Bozovic, Dolores

2012-01-01

Active hair bundle motility has been proposed to underlie the amplification mechanism in the auditory endorgans of non-mammals and in the vestibular systems of all vertebrates, and to constitute a crucial component of cochlear amplification in mammals. We used semi-intact in vitro preparations of the bullfrog sacculus to study the effects of elastic mechanical loading on both natively coupled and freely oscillating hair bundles. For the latter, we attached glass fibers of different stiffness to the stereocilia and observed the induced changes in the spontaneous bundle movement. When driven with sinusoidal deflections, hair bundles displayed phase-locked response indicative of an Arnold Tongue, with the frequency selectivity highest at low amplitudes and decreasing under stronger stimulation. A striking broadening of the mode-locked response was seen with increasing stiffness of the load, until approximate impedance matching, where the phase-locked response remained flat over the physiological range of frequencies. When the otolithic membrane was left intact atop the preparation, the natural loading of the bundles likewise decreased their frequency selectivity with respect to that observed in freely oscillating bundles. To probe for signatures of the active process under natural loading and coupling conditions, we applied transient mechanical stimuli to the otolithic membrane. Following the pulses, the underlying bundles displayed active movement in the opposite direction, analogous to the twitches observed in individual cells. Tracking features in the otolithic membrane indicated that it moved in phase with the bundles. Hence, synchronous active motility evoked in the system of coupled hair bundles by external input is sufficient to displace large overlying structures. PMID:22479461

Parietal EEG alpha suppression time of memory retrieval reflects memory load while the alpha power of memory maintenance is a composite of the visual process according to simultaneous and successive Sternberg memory tasks.

PubMed

Okuhata, Shiho; Kusanagi, Takuya; Kobayashi, Tetsuo

2013-10-25

The present study investigated EEG alpha activity during visual Sternberg memory tasks using two different stimulus presentation modes to elucidate how the presentation mode affected parietal alpha activity. EEGs were recorded from 10 healthy adults during the Sternberg tasks in which memory items were presented simultaneously and successively. EEG power and suppression time (ST) in the alpha band (8-13Hz) were computed for the memory maintenance and retrieval phases. The alpha activity differed according to the presentation mode during the maintenance phase but not during the retrieval phase. Results indicated that parietal alpha power recorded during the maintenance phase did not reflect the memory load alone. In contrast, ST during the retrieval phase increased with the memory load for both presentation modes, indicating a serial memory scanning process, regardless of the presentation mode. These results indicate that there was a dynamic transition in the memory process from the maintenance phase, which was sensitive to external factors, toward the retrieval phase, during which the process converged on the sequential scanning process, the Sternberg task essentially required. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

Player-Tracking Technology: Half-Full or Half-Empty Glass?

PubMed

Buchheit, Martin; Simpson, Ben Michael

2017-04-01

With the ongoing development of microtechnology, player tracking has become one of the most important components of load monitoring in team sports. The 3 main objectives of player tracking are better understanding of practice (provide an objective, a posteriori evaluation of external load and locomotor demands of any given session or match), optimization of training-load patterns at the team level, and decision making on individual players' training programs to improve performance and prevent injuries (eg, top-up training vs unloading sequences, return to play progression). This paper discusses the basics of a simple tracking approach and the need to integrate multiple systems. The limitations of some of the most used variables in the field (including metabolic-power measures) are debated, and innovative and potentially new powerful variables are presented. The foundations of a successful player-monitoring system are probably laid on the pitch first, in the way practitioners collect their own tracking data, given the limitations of each variable, and how they report and use all this information, rather than in the technology and the variables per se. Overall, the decision to use any tracking technology or new variable should always be considered with a cost/benefit approach (ie, cost, ease of use, portability, manpower/ability to affect the training program).

The interdependence of Ca2+ activation, sarcomere length, and power output in the heart.

PubMed

McDonald, Kerry S

2011-07-01

Myocardium generates power to perform external work on the circulation; yet, many questions regarding intermolecular mechanisms regulating power output remain unresolved. Power output equals force × shortening velocity, and some interesting new observations regarding control of these two factors have arisen. While it is well established that sarcomere length tightly controls myocyte force, sarcomere length-tension relationships also appear to be markedly modulated by PKA-mediated phosphorylation of myofibrillar proteins. Concerning loaded shortening, historical models predict independent cross-bridge mechanics; however, it seems that the mechanical state of one population of cross-bridges affects the activity of other cross-bridges by, for example, recruitment of cross-bridges from the non-cycling pool to the cycling force-generating pool during submaximal Ca(2+) activation. This is supported by the findings that Ca(2+) activation levels, myofilament phosphorylation, and sarcomere length are all modulators of loaded shortening and power output independent of their effects on force. This fine tuning of power output probably helps optimize myocardial energetics and to match ventricular supply with peripheral demand; yet, the discernment of the chemo-mechanical signals that modulate loaded shortening needs further clarification since power output may be a key convergent point and feedback regulator of cytoskeleton and cellular signals that control myocyte growth and survival.

Structure based mechanism of the Ca(2+)-induced release of coelenterazine from the Renilla binding protein.

PubMed

Stepanyuk, Galina A; Liu, Zhi-Jie; Vysotski, Eugene S; Lee, John; Rose, John P; Wang, Bi-Cheng

2009-02-15

The crystal structure of the Ca(2+)-loaded coelenterazine-binding protein from Renilla muelleri in its apo-state has been determined at resolution 1.8 A. Although calcium binding hardly affects the compact scaffold and overall fold of the structure before calcium addition, there are easily discerned shifts in the residues that were interacting with the coelenterazine and a repositioning of helices, to expose a cavity to the external solvent. Altogether these changes offer a straightforward explanation for how following the addition of Ca(2+), the coelenterazine could escape and become available for bioluminescence on Renilla luciferase. A docking computation supports the possibility of a luciferase-binding protein complex. c) 2008 Wiley-Liss, Inc.

Debris/Ice/TPS Assessment and Integrated Photographic Analysis of Shuttle Mission STS-86

NASA Technical Reports Server (NTRS)

Katnik, Gregory N.; Lin, Jill D.

1997-01-01

A debris/ice/thermal protection system assessment and integrated photographic analysis was conducted for Shuttle mission STS-86. Debris inspections of the flight elements and launch pad were performed before and after launch. Icing conditions on the External Tank were assessed by the use of computer programs and infrared scanned data during cryogenic loading of the vehicle, followed by on-pad visual inspection. High speed photography of the launch was analyzed to identify ice/debris sources and evaluate potential vehicle damage and/or in-flight anomalies. This report documents the ice/debris/thermal protection system conditions and integrated photographic analysis of Space Shuttle mission STS-86 and the resulting affect on the Space Shuttle Program.

Strength analysis of an aircraft turbo-compressor engine turbine disc

NASA Astrophysics Data System (ADS)

Klimko, Marek

2017-09-01

This article deals with a strength analysis of a gas turbine rotor disc of the concrete type of an aircraft turbo-compressor engine (ATCE). The introductory part is dedicated to a basic description of the given engine, including the main technical parameters entering the calculation. The calculation is carried out by the finite difference method. This method allows to determine the tension of a generally shaped disc, which is affected by centrifugal forces of its weight, external load and heat stress caused by the difference of thermal gradients along the disc radius. The result of calculations are dependencies of the most important parameters, such as the reduced stress, radial stress, or the safety coefficient along the disc radius.

Loads and loads and loads: the influence of prospective load, retrospective load, and ongoing task load in prospective memory.

PubMed

Meier, Beat; Zimmermann, Thomas D

2015-01-01

In prospective memory tasks different kinds of load can occur. Adding a prospective memory task can impose a load on ongoing task performance. Adding ongoing task load (OTL) can affect prospective memory performance. The existence of multiple target events increases prospective load (PL) and adding complexity to the to-be-remembered action increases retrospective load (RL). In two experiments, we systematically examined the effects of these different types of load on prospective memory performance. Results showed an effect of PL on costs in the ongoing task for categorical targets (Experiment 2), but not for specific targets (Experiment 1). RL and OTL both affected remembering the retrospective component of the prospective memory task. We suggest that PL can enhance costs in the ongoing task due to additional monitoring requirements. RL and OTL seem to impact the division of resources between the ongoing task and retrieval of the retrospective component, which may affect disengagement from the ongoing task. In general, the results demonstrate that the different types of load affect prospective memory differentially.

Loads and loads and loads: the influence of prospective load, retrospective load, and ongoing task load in prospective memory

PubMed Central

Meier, Beat; Zimmermann, Thomas D.

2015-01-01

In prospective memory tasks different kinds of load can occur. Adding a prospective memory task can impose a load on ongoing task performance. Adding ongoing task load (OTL) can affect prospective memory performance. The existence of multiple target events increases prospective load (PL) and adding complexity to the to-be-remembered action increases retrospective load (RL). In two experiments, we systematically examined the effects of these different types of load on prospective memory performance. Results showed an effect of PL on costs in the ongoing task for categorical targets (Experiment 2), but not for specific targets (Experiment 1). RL and OTL both affected remembering the retrospective component of the prospective memory task. We suggest that PL can enhance costs in the ongoing task due to additional monitoring requirements. RL and OTL seem to impact the division of resources between the ongoing task and retrieval of the retrospective component, which may affect disengagement from the ongoing task. In general, the results demonstrate that the different types of load affect prospective memory differentially. PMID:26082709

Structural Health Monitoring in Composite Structures by Fiber-Optic Sensors.

PubMed

Güemes, Alfredo; Fernández-López, Antonio; F Díaz-Maroto, Patricia; Lozano, Angel; Sierra-Perez, Julian

2018-04-04

Fiber-optic sensors cannot measure damage; to get information about damage from strain measurements, additional strategies are needed, and several alternatives are available in the existing literature. This paper discusses two independent procedures. The first is based on detecting new strains appearing around a damage spot. The structure does not need to be under loads, the technique is very robust, and damage detectability is high, but it requires sensors to be located very close to the damage, so it is a local technique. The second approach offers wider coverage of the structure; it is based on identifying the changes caused by damage on the strain field in the whole structure for similar external loads. Damage location does not need to be known a priori, and detectability is dependent upon the sensor's network density, the damage size, and the external loads. Examples of application to real structures are given.

The research and preparation of a novel nano biodegradable polymer external reinforcement

NASA Astrophysics Data System (ADS)

Zhang, Xiangman; Chen, Bin; Fu, Weiguo; Fang, Zhengdong; Liu, Zhenjie; Lu, Weifeng; Shi, Zhengyu; Chen, Lili; Chen, Tao

2011-10-01

The use of current drug-loaded vascular scaffolds is limited in sustained drug release and stability studies in clinical and preclinical trials. We found that poly( L-glutamic acid)-b-poly(propylene oxide)-b-poly( L-glutamic acid) (PLGA-b-PPO-b-PLGA) triblock copolymers can deliver multiple poorly water-soluble drugs (e.g., Paclitaxel) at clinically relevant doses. In this study, we synthesized a new drug-loaded vascular external graft with electrospun nanofibrous scaffolds [poly( L-lactide-co-ɛ-caprolactone) (PLCL):fibrinogen; 2:1 (w/w)] and drug-loaded PLGA-b-PPO-b-PLGA micelles. Cell proliferation and viability assay results showed that beagle smooth muscle cells grew well on the surface of vascular graft-coated micelles at a percentages of 10% (w/w) GPG:PLCL-fibrinogen. This study demonstrates that micelle-coated electrospun PLCL-fibrinogen vascular scaffolds have potential applications in vascular tissue engineering.

Structural Health Monitoring in Composite Structures by Fiber-Optic Sensors †

PubMed Central

Güemes, Alfredo; Díaz-Maroto, Patricia F.; Lozano, Angel; Sierra-Perez, Julian

2018-01-01

Fiber-optic sensors cannot measure damage; to get information about damage from strain measurements, additional strategies are needed, and several alternatives are available in the existing literature. This paper discusses two independent procedures. The first is based on detecting new strains appearing around a damage spot. The structure does not need to be under loads, the technique is very robust, and damage detectability is high, but it requires sensors to be located very close to the damage, so it is a local technique. The second approach offers wider coverage of the structure; it is based on identifying the changes caused by damage on the strain field in the whole structure for similar external loads. Damage location does not need to be known a priori, and detectability is dependent upon the sensor’s network density, the damage size, and the external loads. Examples of application to real structures are given. PMID:29617345

Dual-task and anticipation impact lower limb biomechanics during a single-leg cut with body borne load.

PubMed

Seymore, Kayla D; Cameron, Sarah E; Kaplan, Jonathan T; Ramsay, John W; Brown, Tyler N

2017-12-08

This study quantified how a dual cognitive task impacts lower limb biomechanics during anticipated and unanticipated single-leg cuts with body borne load. Twenty-four males performed anticipated and unanticipated cuts with and without a dual cognitive task with three load conditions: no load (∼6 kg), medium load (15% of BW), and heavy load (30% of BW). Lower limb biomechanics were submitted to a repeated measures linear mixed model to test the main and interaction effects of load, anticipation, and dual task. With body borne load, participants increased peak stance (PS) hip flexion (p = .004) and hip internal rotation (p = .001) angle, and PS hip flexion (p = .001) and internal rotation (p = .018), and knee flexion (p = .016) and abduction (p = .001) moments. With the dual task, participants decreased PS knee flexion angle (p < .001) and hip flexion moment (p = .027), and increased PS knee external rotation angle (p = .034). During the unanticipated cut, participants increased PS hip (p = .040) and knee flexion angle (p < .001), and decreased PS hip adduction (p = .001), and knee abduction (p = .005) and external rotation (p = .026) moments. Adding body borne load produces lower limb biomechanical adaptations thought to increase risk of musculoskeletal injury, but neither anticipation nor dual task exaggerated those biomechanical adaptations. With a dual task, participants adopted biomechanics known to increase injury risk; whereas, participants used lower limb biomechanics thought to decrease injury risk during unanticipated cuts. Copyright © 2017 Elsevier Ltd. All rights reserved.

Relationship Between Pretraining Subjective Wellness Measures, Player Load, and Rating-of-Perceived-Exertion Training Load in American College Football.

PubMed

Govus, Andrew D; Coutts, Aaron; Duffield, Rob; Murray, Andrew; Fullagar, Hugh

2018-01-01

The relationship between pretraining subjective wellness and external and internal training load in American college football is unclear. To examine the relationship of pretraining subjective wellness (sleep quality, muscle soreness, energy, wellness Z score) with player load and session rating of perceived exertion (s-RPE-TL) in American college football players. Subjective wellness (measured using 5-point, Likert-scale questionnaires), external load (derived from GPS and accelerometry), and s-RPE-TL were collected during 3 typical training sessions per week for the second half of an American college football season (8 wk). The relationship of pretraining subjective wellness with player load and s-RPE training load was analyzed using linear mixed models with a random intercept for athlete and a random slope for training session. Standardized mean differences (SMDs) denote the effect magnitude. A 1-unit increase in wellness Z score and energy was associated with trivial 2.3% (90% confidence interval [CI] 0.5, 4.2; SMD 0.12) and 2.6% (90% CI 0.1, 5.2; SMD 0.13) increases in player load, respectively. A 1-unit increase in muscle soreness (players felt less sore) corresponded to a trivial 4.4% (90% CI -8.4, -0.3; SMD -0.05) decrease in s-RPE training load. Measuring pretraining subjective wellness may provide information about players' capacity to perform in a training session and could be a key determinant of their response to the imposed training demands American college football. Hence, monitoring subjective wellness may aid in the individualization of training prescription in American college football players.

Spinal loads as influenced by external loads: a combined in vivo and in silico investigation.

PubMed

Zander, Thomas; Dreischarf, Marcel; Schmidt, Hendrik; Bergmann, Georg; Rohlmann, Antonius

2015-02-26

Knowledge of in vivo spinal loads and muscle forces remains limited but is necessary for spinal biomechanical research. To assess the in vivo spinal loads, measurements with telemeterised vertebral body replacements were performed in four patients. The following postures were investigated: (a) standing with arms hanging down on sides, (b) holding dumbbells to subject the patient to a vertical load, and (c) the forward elevation of arms for creating an additional flexion moment. The same postures were simulated by an inverse static model for validation purposes, to predict muscle forces, and to assess the spinal loads in subjects without implants. Holding dumbbells on sides increased implant forces by the magnitude of the weight of the dumbbells. In contrast, elevating the arms yielded considerable implant forces with a high correlation between the external flexion moment and the implant force. Predictions agreed well with experimental findings, especially for forward elevation of arms. Flexion moments were mainly compensated by erector spinae muscles. The implant altered the kinematics and, thus, the spinal loads. Elevation of both arms in vivo increased spinal axial forces by approximately 100N; each additional kg of dumbbell weight held in the hands increased the spinal axial forces by 60N. Model predictions suggest that in the intact situation, the force increase is one-third greater for these loads. In vivo measurements are essential for the validation of analytical models, and the combination of both methods can reveal unquantifiable data such as the spinal loads in the intact non-instrumented situation. Copyright © 2015 Elsevier Ltd. All rights reserved.

Relationships between alexithymia, affect recognition, and empathy after traumatic brain injury.

PubMed

Neumann, Dawn; Zupan, Barbra; Malec, James F; Hammond, Flora

2014-01-01

To determine (1) alexithymia, affect recognition, and empathy differences in participants with and without traumatic brain injury (TBI); (2) the amount of affect recognition variance explained by alexithymia; and (3) the amount of empathy variance explained by alexithymia and affect recognition. Sixty adults with moderate-to-severe TBI; 60 age and gender-matched controls. Participants were evaluated for alexithymia (difficulty identifying feelings, difficulty describing feelings, and externally-oriented thinking); facial and vocal affect recognition; and affective and cognitive empathy (empathic concern and perspective-taking, respectively). Participants with TBI had significantly higher alexithymia; poorer facial and vocal affect recognition; and lower empathy scores. For TBI participants, facial and vocal affect recognition variances were significantly explained by alexithymia (12% and 8%, respectively); however, the majority of the variances were accounted for by externally-oriented thinking alone. Affect recognition and alexithymia significantly accounted for 16.5% of cognitive empathy. Again, the majority of the variance was primarily explained by externally-oriented thinking. Affect recognition and alexithymia did not explain affective empathy. Results suggest that people who have a tendency to avoid thinking about emotions (externally-oriented thinking) are more likely to have problems recognizing others' emotions and assuming others' points of view. Clinical implications are discussed.

Biomechanical and biophysical environment of bone from the macroscopic to the pericellular and molecular level.

PubMed

Ren, Li; Yang, Pengfei; Wang, Zhe; Zhang, Jian; Ding, Chong; Shang, Peng

2015-10-01

Bones with complicated hierarchical configuration and microstructures constitute the load-bearing system. Mechanical loading plays an essential role in maintaining bone health and regulating bone mechanical adaptation (modeling and remodeling). The whole-bone or sub-region (macroscopic) mechanical signals, including locomotion-induced loading and external actuator-generated vibration, ultrasound, oscillatory skeletal muscle stimulation, etc., give rise to sophisticated and distinct biomechanical and biophysical environments at the pericellular (microscopic) and collagen/mineral molecular (nanoscopic) levels, which are the direct stimulations that positively influence bone adaptation. While under microgravity, the stimulations decrease or even disappear, which exerts a negative influence on bone adaptation. A full understanding of the biomechanical and biophysical environment at different levels is necessary for exploring bone biomechanical properties and mechanical adaptation. In this review, the mechanical transferring theories from the macroscopic to the microscopic and nanoscopic levels are elucidated. First, detailed information of the hierarchical structures and biochemical composition of bone, which are the foundations for mechanical signal propagation, are presented. Second, the deformation feature of load-bearing bone during locomotion is clarified as a combination of bending and torsion rather than simplex bending. The bone matrix strains at microscopic and nanoscopic levels directly induced by bone deformation are critically discussed, and the strain concentration mechanism due to the complicated microstructures is highlighted. Third, the biomechanical and biophysical environments at microscopic and nanoscopic levels positively generated during bone matrix deformation or by dynamic mechanical loadings induced by external actuators, as well as those negatively affected under microgravity, are systematically discussed, including the interstitial fluid flow (IFF) within the lacunar-canalicular system and at the endosteum, the piezoelectricity at the deformed bone surface, and the streaming potential accompanying the IFF. Their generation mechanisms and the regulation effect on bone adaptation are presented. The IFF-induced chemotransport effect, shear stress, and fluid drag on the pericellular matrix are meaningful and noteworthy. Furthermore, we firmly believe that bone adaptation is regulated by the combination of bone biomechanical and biophysical environment, not only the commonly considered matrix strain, fluid shear stress, and hydrostatic pressure, but also the piezoelectricity and streaming potential. Especially, it is necessary to incorporate bone matrix piezoelectricity and streaming potential to explain how osteoblasts (bone formation cells) and osteoclasts (bone resorption cells) can differentiate among different types of loads. Specifically, the regulation effects and the related mechanisms of the biomechanical and biophysical environments on bone need further exploration, and the incorporation of experimental research with theoretical simulations is essential. Copyright © 2015. Published by Elsevier Ltd.

Stress-intensity factors of r-cracks in fiber-reinforced composites under thermal and mechanical loading

NASA Astrophysics Data System (ADS)

Mueller, W. H.; Schmauder, S.

1993-02-01

The plane stress/plane strain problem of radial matrix cracking in fiber-reinforced composites, due to thermal mismatch and externally applied stress is solved numerically in the framework of linear elasticity, using Erdogan's integral equation technique. It is shown that, in order to obtain the results of the combined loading case, the solutions of purely thermal and purely mechanical loading can simply be superimposed. Stress-intensity factors are calculated for various lengths and distances of the crack from the interface for each of these loading conditions.

Axial displacement of external and internal implant-abutment connection evaluated by linear mixed model analysis.

PubMed

Seol, Hyon-Woo; Heo, Seong-Joo; Koak, Jai-Young; Kim, Seong-Kyun; Kim, Shin-Koo

2015-01-01

To analyze the axial displacement of external and internal implant-abutment connection after cyclic loading. Three groups of external abutments (Ext group), an internal tapered one-piece-type abutment (Int-1 group), and an internal tapered two-piece-type abutment (Int-2 group) were prepared. Cyclic loading was applied to implant-abutment assemblies at 150 N with a frequency of 3 Hz. The amount of axial displacement, the Periotest values (PTVs), and the removal torque values(RTVs) were measured. Both a repeated measures analysis of variance and pattern analysis based on the linear mixed model were used for statistical analysis. Scanning electron microscopy (SEM) was used to evaluate the surface of the implant-abutment connection. The mean axial displacements after 1,000,000 cycles were 0.6 μm in the Ext group, 3.7 μm in the Int-1 group, and 9.0 μm in the Int-2 group. Pattern analysis revealed a breakpoint at 171 cycles. The Ext group showed no declining pattern, and the Int-1 group showed no declining pattern after the breakpoint (171 cycles). However, the Int-2 group experienced continuous axial displacement. After cyclic loading, the PTV decreased in the Int-2 group, and the RTV decreased in all groups. SEM imaging revealed surface wear in all groups. Axial displacement and surface wear occurred in all groups. The PTVs remained stable, but the RTVs decreased after cyclic loading. Based on linear mixed model analysis, the Ext and Int-1 groups' axial displacements plateaued after little cyclic loading. The Int-2 group's rate of axial displacement slowed after 100,000 cycles.

The effect of external ankle support on knee and ankle joint movement and loading in netball players.

PubMed

Vanwanseele, Benedicte; Stuelcken, Max; Greene, Andrew; Smith, Richard

2014-09-01

External ankle support has been successfully used to prevent ankle sprains. However, some recent studies have indicated that reducing ankle range of motion can place larger loads on the knee. The aim of this study was to investigate the effect of external ankle support (braces and high-top shoes) on the ankle and knee joint loading during a netball specific landing task. A repeated measure design. High performance netball players with no previously diagnosed severe ankle or knee injury (n=11) were recruited from NSW Institute of Sport netball programme. The kinematic and kinetic data were collected simultaneously using a 3-D Motion Analysis System and one Kistler force plate to measure ground reaction forces. Players performed a single leg landing whilst receiving a pass while wearing a standard netball shoe, the same shoe with a lace-up brace and a high-top shoe. Only the brace condition significantly reduced the ankle range of motion in the frontal plane (in/eversion) by 3.95 ± 3.74 degrees compared to the standard condition. No changes were found for the knee joint loading in the brace condition. The high-top shoes acted to increase the peak knee internal rotation moment by 15%. Both the brace and high-top conditions brought about increases in the peak ankle plantar flexion moment during the landing phase. Lace-up braces can be used by netball players to restrict ankle range of motion during a single leg landing while receiving a pass without increasing the load on the knee joint. Copyright © 2013 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

A new device to study isoload eccentric exercise.

PubMed

Guilhem, Gaël; Cornu, Christophe; Nordez, Antoine; Guével, Arnaud

2010-12-01

This study was designed to develop a new device allowing mechanical analysis of eccentric exercise against a constant load, with a view in mind to compare isoload (IL) and isokinetic (IK) eccentric exercises. A plate-loaded resistance training device was integrated to an IK dynamometer, to perform the acquisition of mechanical parameters (i.e., external torque, angular velocity). To determine the muscular torque produced by the subject, load torque was experimentally measured (TLexp) at 11 different loads from 30° to 90° angle (0° = lever arm in horizontal position). TLexp was modeled to take friction effect and torque variations into account. Validity of modeled load torque (TLmod) was tested by determining the root mean square (RMS) error, bias, and 2SD between the descending part of TLexp (from 30° to 90°) and TLmod. Validity of TLexp was tested by a linear regression and a Passing-Bablok regression. A pilot analysis on 10 subjects was performed to determine the contribution of the torque because of the moment of inertia to the amount of external work (W). Results showed the validity of TLmod (bias = 0%; RMS error = 0.51%) and TLexp SEM = 4.1 N·m; Intraclass correlation coefficient (ICC) = 1.00; slope = 0.99; y-intercept = -0.13). External work calculation showed a satisfactory reproducibility (SEM = 38.3 J; ICC = 0.98) and moment of inertia contribution to W showed a low value (3.2 ± 2.0%). Results allow us to validate the new device developed in this study. Such a device could be used in future work to study IL eccentric exercise and to compare the effect of IL and IK eccentric exercises in standardized conditions.

Investigation of the Loads on a Conventional Front and Rear Sliding Canopy

NASA Technical Reports Server (NTRS)

Dexter, Howard E.; Rickey, Edward A.

1947-01-01

As one phase of a comprehensive canopy load investigation, conventional front and rear sliding canopies which are typified by installation on the SB2C-4E airplane, were tested in the Langley full-scale tunnel to determine the pressure distributions and the aerodynamic loads on the canopies. A preliminary analysis of the results of these tests is presented in this report. Plots are presented that show the distribution of pressure at four longitudinal stations through each canopy for a range of conditions selected to determine the effects of varying canopy position, yaw, lift coefficient, and power. The results indicate that the maximum loads, based on the external-internal pressure differential, for the front and rear canopies were obtained with the airplane simulating the high speed flight condition. The highest loading on the front canopy was in the exploding direction for the configuration with the front and rear canopies closed. The highest loads on the rear canopy were in the crushing direction with the front canopy open and the rear canopy closed. For most of the simulated flight conditions, the highest loads on the front canopy, per unit area, were over twice as great as the highest loads on the rear canopy when the comparison was made for the most critical canopy configuration in each case. The external pressure distribution over the front and rear canopies, which were fairly symmetrical to 0 degree angle of yaw, were greatly distorted at other yaw attitudes, particularly for the propeller operating conditions. These distorted pressure distributions resulted in local exploding and crushing loads on both canopies which were often considerably higher than the average canopy loads.

Oxidation of a Commercial Nickel-Based Superalloy under Static Loading

NASA Astrophysics Data System (ADS)

Foss, B. J.; Hardy, M. C.; Child, D. J.; McPhail, D. S.; Shollock, B. A.

2014-12-01

The current demands of the aviation industry for increased gas-turbine efficiency necessitate higher turbine entry temperatures, requiring that alloys exhibit superior oxidation resistance. The synergistic effects of oxidation and mechanical stresses pose a complex issue. The purpose of the current research was to examine the effects of stress on the oxidation and oxygen transport in a commercial nickel-based superalloy. Fine grain RR1000 in both polished and shot-peened conditions was studied for classic (zero load) and statically loaded conditions using integrated two-stage isotopic tracing combined with focused-ion-beam secondary ion mass spectrometry (FIB-SIMS). Cr2O3 external oxide formed with semicontinuous TiO2 above and below. Preferential grain boundary Al2O3 internal oxide formation, γ'-dissolution, and recrystallization occurred subsurface. Oxidation mechanisms were dominated by anionic/cationic growth in the external oxide with inward oxygen transport, initially through the partially unprotective external oxide, then along internal oxide/alloy interfaces. Loading did not influence the oxidation products formed but did bring about expedited oxidation kinetics and changes to the oxide morphology. The oxygen diffusivity D {O/ * } (×10-13 cm2s-1) ranged from 0.39 for the polished alloy to 3.7 for the shot-peened condition under compressive stress. Arguably, the most significant effects took place in the subsurface regions. Increased oxidation kinetics were attributed to the development of fast cation diffusion paths as the alloy deformed by creep.

Simulation of Propellant Loading System Senior Design Implement in Computer Algorithm

NASA Technical Reports Server (NTRS)

Bandyopadhyay, Alak

2010-01-01

Propellant loading from the Storage Tank to the External Tank is one of the very important and time consuming pre-launch ground operations for the launch vehicle. The propellant loading system is a complex integrated system involving many physical components such as the storage tank filled with cryogenic fluid at a very low temperature, the long pipe line connecting the storage tank with the external tank, the external tank along with the flare stack, and vent systems for releasing the excess fuel. Some of the very important parameters useful for design purpose are the prediction of pre-chill time, loading time, amount of fuel lost, the maximum pressure rise etc. The physics involved for mathematical modeling is quite complex due to the fact the process is unsteady, there is phase change as some of the fuel changes from liquid to gas state, then conjugate heat transfer in the pipe walls as well as between solid-to-fluid region. The simulation is very tedious and time consuming too. So overall, this is a complex system and the objective of the work is student's involvement and work in the parametric study and optimization of numerical modeling towards the design of such system. The students have to first become familiar and understand the physical process, the related mathematics and the numerical algorithm. The work involves exploring (i) improved algorithm to make the transient simulation computationally effective (reduced CPU time) and (ii) Parametric study to evaluate design parameters by changing the operational conditions

46 CFR 45.181 - Load line exemption requirements for the Burns Harbor and Milwaukee routes.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 2 2010-10-01 2010-10-01 false Load line exemption requirements for the Burns Harbor... line exemption requirements for the Burns Harbor and Milwaukee routes. Barges operating on the Burns... (Milwaukee and/or Burns Harbor); (4) Design type (covered/uncovered hopper, deck, etc.); (5) External...

KSC-04pd1269

NASA Image and Video Library

2004-04-28

KENNEDY SPACE CENTER, FLA. - With employees walking alongside, the external tank atop its transporter turns the corner from the Vehicle Assembly Building toward the Turn Basin and the Banana River. The tank will be loaded onto the waiting barge and transferred to the Michoud Space Systems Assembly Facility near New Orleans where redesign of the external tank is underway for Return to Flight.

KSC-04pd1268

NASA Image and Video Library

2004-04-28

KENNEDY SPACE CENTER, FLA. - Atop a transporter, the external tank seen here turns the corner from the Vehicle Assembly Building toward the Turn Basin and the Banana River. The tank will be loaded onto the waiting barge and transferred to the Michoud Space Systems Assembly Facility near New Orleans where redesign of the external tank is underway for Return to Flight.

KSC-04PD-1269

NASA Technical Reports Server (NTRS)

2004-01-01

KENNEDY SPACE CENTER, FLA. With employees walking alongside, the external tank atop its transporter turns the corner from the Vehicle Assembly Building toward the Turn Basin and the Banana River. The tank will be loaded onto the waiting barge and transferred to the Michoud Space Systems Assembly Facility near New Orleans where redesign of the external tank is underway for Return to Flight.

KSC-04PD-1268

NASA Technical Reports Server (NTRS)

2004-01-01

KENNEDY SPACE CENTER, FLA. Atop a transporter, the external tank seen here turns the corner from the Vehicle Assembly Building toward the Turn Basin and the Banana River. The tank will be loaded onto the waiting barge and transferred to the Michoud Space Systems Assembly Facility near New Orleans where redesign of the external tank is underway for Return to Flight.

High speed machining of space shuttle external tank liquid hydrogen barrel panel

NASA Technical Reports Server (NTRS)

Hankins, J. D.

1983-01-01

Actual and projected optimum High Speed Machining data for producing shuttle external tank liquid hydrogen barrel panels of aluminum alloy 2219-T87 are reported. The data included various machining parameters; e.g., spindle speeds, cutting speed, table feed, chip load, metal removal rate, horsepower, cutting efficiency, cutter wear (lack of) and chip removal methods.

High speed machining of space shuttle external tank liquid hydrogen barrel panel

NASA Astrophysics Data System (ADS)

Hankins, J. D.

1983-11-01

Actual and projected optimum High Speed Machining data for producing shuttle external tank liquid hydrogen barrel panels of aluminum alloy 2219-T87 are reported. The data included various machining parameters; e.g., spindle speeds, cutting speed, table feed, chip load, metal removal rate, horsepower, cutting efficiency, cutter wear (lack of) and chip removal methods.

Negative Affect Shares Genetic and Environmental Influences with Symptoms of Childhood Internalizing and Externalizing Disorders

ERIC Educational Resources Information Center

Mikolajewski, Amy J.; Allan, Nicholas P.; Hart, Sara A.; Lonigan, Christopher J.; Taylor, Jeanette

2013-01-01

The co-occurrence of internalizing and externalizing disorders suggests that they may have common underlying vulnerability factors. Research has shown that negative affect is moderately positively correlated with both internalizing and externalizing disorders in children. The present study is the first to provide an examination of negative affect…

Changes in driving behavior and cognitive performance with different breath alcohol concentration levels.

PubMed

Liu, Yung-Ching; Fu, Shing-Mei

2007-06-01

This study examines the changes in driving behavior and cognitive performance of drivers with different breath alcohol concentration (BrAC) levels. Eight licensed drivers, aged between 20 and 30 years, with BrAC levels of 0.00, 0.25, 0.4 and 0.5 mg/l performed simulated driving tests under high- and low-load conditions. Subjects were asked to assess their subjective psychological load at specified intervals and perform various tasks. The outcome was measured in terms of reaction times for task completion, accuracy rates, and driver's driving behavior. The effects of BrAC vary depending on the task. Performance of tasks involving attention shift, information processing, and short-term memory showed significant deterioration with increasing BrAC, while dangerous external vehicle driving behavior occurred only when the BrAC reached 0.4 mg/l and the deterioration was marked. We can conclude that the cognitive faculty is the first to be impaired by drinking resulting in deteriorated performance in tasks related to divided attention, short-term memory, logical reasoning, followed by visual perception. On the other hand, increasing alcohol dose may not pose an immediate impact on the external vehicle driving behavior but may negatively affect the driver's motor behavior even at low BrAC levels. Experience and will power could compensate for the negative influence of alcohol enabling the drivers to remain in full steering control. This lag between alcohol consumption and impaired driving performance may mislead the drivers in thinking that they are still capable of safe steering and cause them to ignore the potential dangers of drunk driving.

Evaluation of a load cell model for dynamic calibration of the rotor systems research aircraft

NASA Technical Reports Server (NTRS)

Duval, R. W.; Bahrami, H.; Wellman, B.

1985-01-01

The Rotor Systems Research Aircraft uses load cells to isolate the rotor/transmission system from the fuselage. An analytical model of the relationship between applied rotor loads and the resulting load cell measurements is derived by applying a force-and-moment balance to the isolated rotor/transmission system. The model is then used to estimate the applied loads from measured load cell data, as obtained from a ground-based shake test. Using nominal design values for the parameters, the estimation errors, for the case of lateral forcing, were shown to be on the order of the sensor measurement noise in all but the roll axis. An unmodeled external load appears to be the source of the error in this axis.

Vibration Analysis of the Space Shuttle External Tank Cable Tray Flight Data With and Without PAL Ramp

NASA Technical Reports Server (NTRS)

Walker, Bruce E.; Panda, Jayanta; Sutliff, Daniel L.

2008-01-01

External Tank Cable Tray vibration data for three successive Space Shuttle flights were analyzed to assess response to buffet and the effect of removal of the Protuberance Air Loads (PAL) ramp. Waveform integration, spectral analysis, cross-correlation analysis and wavelet analysis were employed to estimate vibration modes and temporal development of vibration motion from a sparse array of accelerometers and an on-board system that acquired 16 channels of data for approximately the first 2 min of each flight. The flight data indicated that PAL ramp removal had minimal effect on the fluctuating loads on the cable tray. The measured vibration frequencies and modes agreed well with predicted structural response.

Vibration Analysis of the Space Shuttle External Tank Cable Tray Flight Data with and without PAL Ramp

NASA Technical Reports Server (NTRS)

Walker, B. E.; Panda, B. E.; Sutliff, D. L.

2008-01-01

External Tank Cable Tray vibration data for three successive Space Shuttle flights were analyzed to assess response to buffet and the effect of removal of the Protuberance Air Loads (PAL) ramp. Waveform integration, spectral analysis, cross-correlation analysis and wavelet analysis were employed to estimate vibration modes and temporal development of vibration motion from a sparse array of accelerometers and an on-board system that acquired 16 channels of data for approximately the first two minutes of each flight. The flight data indicated that PAL ramp removal had minimal effect on the fluctuating loads on the cable tray. The measured vibration frequencies and modes agreed well with predicted structural response.

Optimization of power generating thermoelectric modules utilizing LNG cold energy

NASA Astrophysics Data System (ADS)

Jeong, Eun Soo

2017-12-01

A theoretical investigation to optimize thermoelectric modules, which convert LNG cold energy into electrical power, is performed using a novel one-dimensional analytic model. In the model the optimum thermoelement length and external load resistance, which maximize the energy conversion ratio, are determined by the heat supplied to the cold heat reservoir, the hot and cold side temperatures, the thermal and electrical contact resistances and the properties of thermoelectric materials. The effects of the thermal and electrical contact resistances and the heat supplied to the cold heat reservoir on the maximum energy conversion ratio, the optimum thermoelement length and the optimum external load resistance are shown.

External nutrient sources, internal nutrient pools, and phytoplankton production in Chesapeake Bay

DOE Office of Scientific and Technical Information (OSTI.GOV)

Magnien, R.E.; Summers, R.M.; Sellner, K.G.

1992-12-01

External nutrient loadings, internal nutrient pools, and phytoplankton production were examined for three major subsystems of the Chesapeake Bay Estuary-the upper Mainstem, the Patuxent Estuary, and the Potomac Estuary-during 1985-1989. The atomic nitrogen to phosphorus ratios (TN:TP) of total loads were 51, 29 and 35, respectively. Most of these loads entered at the head of the estuaries from riverine sources and major wastewater treatment plants. Seven-16% of the nitrogen load entered the head of each estuary as particulate matter in contrast to 48-69% for phosphorus. The difference seems to favor a greater loss of phosphorus than nitrogen through sedimentation andmore » burial. A major storm event in the Potomac watershed greatly increased the particulate fraction of nitrogen and phosphorus and lowered the TN:TP in the river-borne loads and accounted for 11% of the nitrogen and 31% of the phosphorus delivered to the estuary by the Potomac River during the entire 60- month period examined here. Within the Mainstem estuary, salinity dilution plots revealed strong net sources of ammonium and phosphate in the oligohaline to upper mesohaline region. indicating considerable internal recycling of nutrients to surface waters. A net sink of nitrate was indicated during summer. Phytoplankton biomass in the mesohaline Mainstem reached a peak in spring and was relatively constant throughout the other seasons. In the Patuxent and Potomac, the TN:TP ratios of external loads are 2-4 times higher than those observed over the previous two decades. These changes are attributed to point-source phosphorus controls and the likelihood that nitrogen-rich nonpoint source inputs, including contributions from the atmosphere, have increased. These higher N:P ratios now suggest a greater overall potential for phosphorus-limitation rather than nitrogen-limitation of phytoplankton in the areas studied. 66 refs., 6 figs., 7 tabs.« less

Decrease of dynamic loads in mobile energy means

NASA Astrophysics Data System (ADS)

Polivaev, O. I.; Gorban, L. K.; Vorohobin, A. V.; Vedrinsky, O. S.

2018-03-01

The increase in the productivity of machine and tractor units is possible due to the increase in operating speeds, this leads to the emergence of increased dynamic loads in the system “engine-transmission-propulsion unit-soil”, which worsens the performance of machine-tractor aggregates. To reduce fluctuations in the “engine-transmission” system, special vibration dampers are used, which installed in close proximity to the engine and protect well the transmission from uneven engine operation; however, such dampers practically do not eliminate the oscillations of external loads. Reducing dynamic loads on the transmission and the mobile power engine (MPE) is an important issue directly related to improving the performance, reliability and durability of the tractor, as well as reducing the slippage of the drive wheels. In order to reduce effectively dynamic loads on the transmission and on the MPE, it is necessary to introduce resilient damping elements closer to the sources of oscillations, namely, to the driving wheels. At the same time, the elastic-damping element should provide accumulation of vibration energy caused by external influences and have a large energy capacity. The installation of an elastic-damping element in the final link of the tractor transmission ensures a reduction in the magnitude of external influences, thereby protecting the engine and transmission from large dynamic loads, and allows one to reduce the slippage of the propellers, which has a positive effect on the traction and energy characteristics of the tractor. Traction tests of the LTP-55 tractor on a concrete road showed that the use of an elasto-damping drive makes it possible to increase the maximum tractive power from 33.5 to 35.3 kW and to reduce the slipping of propellers by 12-30%, the specific fuel consumption by 6-10%. When driving on stubble, the use of an elastic-damping drive increases the maximum tractive power from 25 to 26 kW, reduces the skidding of propellers by 10-28%, and the specific fuel consumption by 10-12.5%.

Perceptual Load Affects Eyewitness Accuracy and Susceptibility to Leading Questions.

PubMed

Murphy, Gillian; Greene, Ciara M

2016-01-01

Load Theory (Lavie, 1995, 2005) states that the level of perceptual load in a task (i.e., the amount of information involved in processing task-relevant stimuli) determines the efficiency of selective attention. There is evidence that perceptual load affects distractor processing, with increased inattentional blindness under high load. Given that high load can result in individuals failing to report seeing obvious objects, it is conceivable that load may also impair memory for the scene. The current study is the first to assess the effect of perceptual load on eyewitness memory. Across three experiments (two video-based and one in a driving simulator), the effect of perceptual load on eyewitness memory was assessed. The results showed that eyewitnesses were less accurate under high load, in particular for peripheral details. For example, memory for the central character in the video was not affected by load but memory for a witness who passed by the window at the edge of the scene was significantly worse under high load. High load memories were also more open to suggestion, showing increased susceptibility to leading questions. High visual perceptual load also affected recall for auditory information, illustrating a possible cross-modal perceptual load effect on memory accuracy. These results have implications for eyewitness memory researchers and forensic professionals.

Perceptual Load Affects Eyewitness Accuracy and Susceptibility to Leading Questions

PubMed Central

Murphy, Gillian; Greene, Ciara M.

2016-01-01

Load Theory (Lavie, 1995, 2005) states that the level of perceptual load in a task (i.e., the amount of information involved in processing task-relevant stimuli) determines the efficiency of selective attention. There is evidence that perceptual load affects distractor processing, with increased inattentional blindness under high load. Given that high load can result in individuals failing to report seeing obvious objects, it is conceivable that load may also impair memory for the scene. The current study is the first to assess the effect of perceptual load on eyewitness memory. Across three experiments (two video-based and one in a driving simulator), the effect of perceptual load on eyewitness memory was assessed. The results showed that eyewitnesses were less accurate under high load, in particular for peripheral details. For example, memory for the central character in the video was not affected by load but memory for a witness who passed by the window at the edge of the scene was significantly worse under high load. High load memories were also more open to suggestion, showing increased susceptibility to leading questions. High visual perceptual load also affected recall for auditory information, illustrating a possible cross-modal perceptual load effect on memory accuracy. These results have implications for eyewitness memory researchers and forensic professionals. PMID:27625628

Lateral Load Testing of the Advanced Stirling Convertor (ASC-E2) Heater Head

NASA Technical Reports Server (NTRS)

Cornell, Peggy A.; Krause, David L.; Davis, Glen; Robbie, Malcolm G.; Gubics, David A.

2010-01-01

Free-piston Stirling convertors are fundamental to the development of NASA s next generation of radioisotope power system, the Advanced Stirling Radioisotope Generator (ASRG). The ASRG will use General Purpose Heat Source (GPHS) modules as the energy source and Advanced Stirling Convertors (ASCs) to convert heat into electrical energy, and is being developed by Lockheed Martin under contract to the Department of Energy. Achieving flight status mandates that the ASCs satisfy design as well as flight requirements to ensure reliable operation during launch. To meet these launch requirements, GRC performed a series of quasi-static mechanical tests simulating the pressure, thermal, and external loading conditions that will be experienced by an ASC-E2 heater head assembly. These mechanical tests were collectively referred to as "lateral load tests" since a primary external load lateral to the heater head longitudinal axis was applied in combination with the other loading conditions. The heater head was subjected to the operational pressure, axial mounting force, thermal conditions, and axial and lateral launch vehicle acceleration loadings. To permit reliable prediction of the heater head s structural performance, GRC completed Finite Element Analysis (FEA) computer modeling for the stress, strain, and deformation that will result during launch. The heater head lateral load test directly supported evaluation of the analysis and validation of the design to meet launch requirements. This paper provides an overview of each element within the test and presents assessment of the modeling as well as experimental results of this task.

Lateral Load Testing of the Advanced Stirling Convertor (ASC-E2) Heater Head

NASA Technical Reports Server (NTRS)

Cornell, Peggy A.; Krause, David L.; Davis, Glen; Robbie, Malcolm G.; Gubics, David A.

2011-01-01

Free-piston Stirling convertors are fundamental to the development of NASA s next generation of radioisotope power system, the Advanced Stirling Radioisotope Generator (ASRG). The ASRG will use General Purpose Heat Source (GPHS) modules as the energy source and Advanced Stirling Convertors (ASCs) to convert heat into electrical energy, and is being developed by Lockheed Martin under contract to the Department of Energy. Achieving flight status mandates that the ASCs satisfy design as well as flight requirements to ensure reliable operation during launch. To meet these launch requirements, GRC performed a series of quasi-static mechanical tests simulating the pressure, thermal, and external loading conditions that will be experienced by an ASC-E2 heater head assembly. These mechanical tests were collectively referred to as "lateral load tests" since a primary external load lateral to the heater head longitudinal axis was applied in combination with the other loading conditions. The heater head was subjected to the operational pressure, axial mounting force, thermal conditions, and axial and lateral launch vehicle acceleration loadings. To permit reliable prediction of the heater head s structural performance, GRC completed Finite Element Analysis (FEA) computer modeling for the stress, strain, and deformation that will result during launch. The heater head lateral load test directly supported evaluation of the analysis and validation of the design to meet launch requirements. This paper provides an overview of each element within the test and presents assessment of the modeling as well as experimental results of this task.

Lateral Load Testing of the Advanced Stirling Convertor (ASC-E2) Heater Head

NASA Technical Reports Server (NTRS)

Cornell, Peggy A.; Krause, David L.; Davis, Glen; Robbie, Malcolm G.; Gubics, David A.

2010-01-01

Free-piston Stirling convertors are fundamental to the development of NASA s next generation of radioisotope power system, the Advanced Stirling Radioisotope Generator (ASRG). The ASRG will use General Purpose Heat Source (GPHS) modules as the energy source and Advanced Stirling Convertors (ASCs) to convert heat into electrical energy, and is being developed by Lockheed Martin under contract to the Department of Energy. Achieving flight status mandates that the ASCs satisfy design as well as flight requirements to ensure reliable operation during launch. To meet these launch requirements, GRC performed a series of quasi-static mechanical tests simulating the pressure, thermal, and external loading conditions that will be experienced by an ASC E2 heater head assembly. These mechanical tests were collectively referred to as lateral load tests since a primary external load lateral to the heater head longitudinal axis was applied in combination with the other loading conditions. The heater head was subjected to the operational pressure, axial mounting force, thermal conditions, and axial and lateral launch vehicle acceleration loadings. To permit reliable prediction of the heater head s structural performance, GRC completed Finite Element Analysis (FEA) computer modeling for the stress, strain, and deformation that will result during launch. The heater head lateral load test directly supported evaluation of the analysis and validation of the design to meet launch requirements. This paper provides an overview of each element within the test and presents assessment of the modeling as well as experimental results of this task.

LOADING MACHINE FOR REACTORS

DOEpatents

Simon, S.L.

1959-07-01

An apparatus is described for loading or charging slugs of fissionable material into a nuclear reactor. The apparatus of the invention is a "muzzle loading" type comprising a delivery tube or muzzle designed to be brought into alignment with any one of a plurality of fuel channels. The delivery tube is located within the pressure shell and it is also disposed within shielding barriers while the fuel cantridges or slugs are forced through the delivery tube by an externally driven flexible ram.

Modeling ARRM Xenon Tank Pressurization Using 1D Thermodynamic and Heat Transfer Equations

NASA Technical Reports Server (NTRS)

Gilligan, Patrick; Tomsik, Thomas

2016-01-01

As a first step in understanding what ground support equipment (GSE) is required to provide external cooling during the loading of 5,000 kg of xenon into 4 aluminum lined composite overwrapped pressure vessels (COPVs), a modeling analysis was performed using Microsoft Excel. The goals of the analysis were to predict xenon temperature and pressure throughout loading at the launch facility, estimate the time required to load one tank, and to get an early estimate of what provisions for cooling xenon might be needed while the tanks are being filled. The model uses the governing thermodynamic and heat transfer equations to achieve these goals. Results indicate that a single tank can be loaded in about 15 hours with reasonable external coolant requirements. The model developed in this study was successfully validated against flight and test data. The first data set is from the Dawn mission which also utilizes solar electric propulsion with xenon propellant, and the second is test data from the rapid loading of a hydrogen cylindrical COPV. The main benefit of this type of model is that the governing physical equations using bulk fluid solid temperatures can provide a quick and accurate estimate of the state of the propellant throughout loading which is much cheaper in terms of computational time and licensing costs than a Computation Fluid Dynamics (CFD) analysis while capturing the majority of the thermodynamics and heat transfer.

Modeling Xenon Tank Pressurization using One-Dimensional Thermodynamic and Heat Transfer Equations

NASA Technical Reports Server (NTRS)

Gilligan, Ryan P.; Tomsik, Thomas M.

2017-01-01

As a first step in understanding what ground support equipment (GSE) is required to provide external cooling during the loading of 5,000 kg of xenon into 4 aluminum lined composite overwrapped pressure vessels (COPVs), a modeling analysis was performed using Microsoft Excel. The goals of the analysis were to predict xenon temperature and pressure throughout loading at the launch facility, estimate the time required to load one tank, and to get an early estimate of what provisions for cooling xenon might be needed while the tanks are being filled. The model uses the governing thermodynamic and heat transfer equations to achieve these goals. Results indicate that a single tank can be loaded in about 15 hours with reasonable external coolant requirements. The model developed in this study was successfully validated against flight and test data. The first data set is from the Dawn mission which also utilizes solar electric propulsion with xenon propellant, and the second is test data from the rapid loading of a hydrogen cylindrical COPV. The main benefit of this type of model is that the governing physical equations using bulk fluid solid temperatures can provide a quick and accurate estimate of the state of the propellant throughout loading which is much cheaper in terms of computational time and licensing costs than a Computation Fluid Dynamics (CFD) analysis while capturing the majority of the thermodynamics and heat transfer.

Gender dimorphic ACL strain in response to combined dynamic 3D knee joint loading: implications for ACL injury risk.

PubMed

Mizuno, Kiyonori; Andrish, Jack T; van den Bogert, Antonie J; McLean, Scott G

2009-12-01

While gender-based differences in knee joint anatomies/laxities are well documented, the potential for them to precipitate gender-dimorphic ACL loading and resultant injury risk has not been considered. To this end, we generated gender-specific models of ACL strain as a function of any six degrees of freedom (6DOF) knee joint load state via a combined cadaveric and analytical approach. Continuously varying joint forces and torques were applied to five male and five female cadaveric specimens and recorded along with synchronous knee flexion and ACL strain data. All data (approximately 10,000 samples) were submitted to specimen-specific regression analyses, affording ACL strain predictions as a function of the combined 6 DOF knee loads. Following individual model verifications, generalized gender-specific models were generated and subjected to 6 DOF external load scenarios consistent with both a clinical examination and a dynamic sports maneuver. The ensuing model-based strain predictions were subsequently examined for gender-based discrepancies. Male and female specimen-specific models predicted ACL strain within 0.51%+/-0.10% and 0.52%+/-0.07% of the measured data respectively, and explained more than 75% of the associated variance in each case. Predicted female ACL strains were also significantly larger than respective male values for both simulated 6 DOF load scenarios. Outcomes suggest that the female ACL will rupture in response to comparatively smaller external load applications. Future work must address the underlying anatomical/laxity contributions to knee joint mechanical and resultant ACL loading, ultimately affording prevention strategies that may cater to individual joint vulnerabilities.

Towards Subject-Specific Strength Training Design through Predictive Use of Musculoskeletal Models.

PubMed

Plüss, Michael; Schellenberg, Florian; Taylor, William R; Lorenzetti, Silvio

2018-01-01

Lower extremity dysfunction is often associated with hip muscle strength deficiencies. Detailed knowledge of the muscle forces generated in the hip under specific external loading conditions enables specific structures to be trained. The aim of this study was to find the most effective movement type and loading direction to enable the training of specific parts of the hip muscles using a standing posture and a pulley system. In a novel approach to release the predictive power of musculoskeletal modelling techniques based on inverse dynamics, flexion/extension and ab-/adduction movements were virtually created. To demonstrate the effectiveness of this approach, three hip orientations and an external loading force that was systematically rotated around the body were simulated using a state-of-the art OpenSim model in order to establish ideal designs for training of the anterior and posterior parts of the M. gluteus medius (GM). The external force direction as well as the hip orientation greatly influenced the muscle forces in the different parts of the GM. No setting was found for simultaneous training of the anterior and posterior parts with a muscle force higher than 50% of the maximum. Importantly, this study has demonstrated the use of musculoskeletal models as an approach to predict muscle force variations for different strength and rehabilitation exercise variations.

Towards Subject-Specific Strength Training Design through Predictive Use of Musculoskeletal Models

PubMed Central

Plüss, Michael; Schellenberg, Florian

2018-01-01

Lower extremity dysfunction is often associated with hip muscle strength deficiencies. Detailed knowledge of the muscle forces generated in the hip under specific external loading conditions enables specific structures to be trained. The aim of this study was to find the most effective movement type and loading direction to enable the training of specific parts of the hip muscles using a standing posture and a pulley system. In a novel approach to release the predictive power of musculoskeletal modelling techniques based on inverse dynamics, flexion/extension and ab-/adduction movements were virtually created. To demonstrate the effectiveness of this approach, three hip orientations and an external loading force that was systematically rotated around the body were simulated using a state-of-the art OpenSim model in order to establish ideal designs for training of the anterior and posterior parts of the M. gluteus medius (GM). The external force direction as well as the hip orientation greatly influenced the muscle forces in the different parts of the GM. No setting was found for simultaneous training of the anterior and posterior parts with a muscle force higher than 50% of the maximum. Importantly, this study has demonstrated the use of musculoskeletal models as an approach to predict muscle force variations for different strength and rehabilitation exercise variations. PMID:29796082

Static-stress analysis of dual-axis confinement vessel

NASA Astrophysics Data System (ADS)

Bultman, D. H.

1992-11-01

This study evaluates the static-pressure containment capability of a 6-ft-diameter, spherical vessel, made of HSLA-100 steel, to be used for high-explosive (HE) containment. The confinement vessel is designed for use with the Dual-Axis Radiographic Hydrotest Facility (DARHT) being developed at Los Alamos National Laboratory. Two sets of openings in the vessel are covered with x-ray transparent covers to allow radiographic imaging of an explosion as it occurs inside the vessel. The confinement vessel is analyzed as a pressure vessel based on the ASME Boiler and Pressure Vessel Code, Section 8, Division 1, and the Welding Research Council Bulletin, WRC-107. Combined stresses resulting from internal pressure and external loads on nozzles are calculated and compared with the allowable stresses for HSLA-100 steel. Results confirm that the shell and nozzles of the confinement vessel are adequately designed to safely contain the maximum residual pressure of 1675 psi that would result from an HE charge of 24.2 kg detonated in a vacuum. Shell stresses at the shell-to-nozzle interface, produced from external loads on the nozzles, were less than 400 psi. The maximum combined stress resulting from the internal pressure plus external loads was 16,070 psi, which is less than half the allowable stress of 42,375 psi for HSLA-100 steel.

Measuring the effect of femoral malrotation on knee joint biomechanics for total knee arthroplasty using computational simulation

PubMed Central

Kang, K-T.; Koh, Y-G.; Son, J.; Kwon, O-R.; Baek, C.; Jung, S. H.

2016-01-01

Objectives Malrotation of the femoral component can result in post-operative complications in total knee arthroplasty (TKA), including patellar maltracking. Therefore, we used computational simulation to investigate the influence of femoral malrotation on contact stresses on the polyethylene (PE) insert and on the patellar button as well as on the forces on the collateral ligaments. Materials and Methods Validated finite element (FE) models, for internal and external malrotations from 0° to 10° with regard to the neutral position, were developed to evaluate the effect of malrotation on the femoral component in TKA. Femoral malrotation in TKA on the knee joint was simulated in walking stance-phase gait and squat loading conditions. Results Contact stress on the medial side of the PE insert increased with internal femoral malrotation and decreased with external femoral malrotation in both stance-phase gait and squat loading conditions. There was an opposite trend in the lateral side of the PE insert case. Contact stress on the patellar button increased with internal femoral malrotation and decreased with external femoral malrotation in both stance-phase gait and squat loading conditions. In particular, contact stress on the patellar button increased by 98% with internal malrotation of 10° in the squat loading condition. The force on the medial collateral ligament (MCL) and the lateral collateral ligament (LCL) increased with internal and external femoral malrotations, respectively. Conclusions These findings provide support for orthopaedic surgeons to determine a more accurate femoral component alignment in order to reduce post-operative PE problems. Cite this article: K-T. Kang, Y-G. Koh, J. Son, O-R. Kwon, C. Baek, S. H. Jung, K. K. Park. Measuring the effect of femoral malrotation on knee joint biomechanics for total knee arthroplasty using computational simulation. Bone Joint Res 2016;5:552–559. DOI: 10.1302/2046-3758.511.BJR-2016-0107.R1. PMID:28094763

A modeling study examining the impact of nutrient boundaries ...

EPA Pesticide Factsheets

A mass balance eutrophication model, Gulf of Mexico Dissolved Oxygen Model (GoMDOM), has been developed and applied to describe nitrogen, phosphorus and primary production in the Louisiana shelf of the Gulf of Mexico. Features of this model include bi-directional boundary exchanges, an empirical site-specific light attenuation equation, estimates of 56 river loads and atmospheric loads. The model was calibrated for 2006 by comparing model output to observations in zones that represent different locations in the Gulf. The model exhibited reasonable skill in simulating the phosphorus and nitrogen field data and primary production observations. The model was applied to generate a nitrogen mass balance estimate, to perform sensitivity analysis to compare the importance of the nutrient boundary concentrations versus the river loads on nutrient concentrations and primary production within the shelf, and to provide insight into the relative importance of different limitation factors on primary production. The mass budget showed the importance of the rivers as the major external nitrogen source while the atmospheric load contributed approximately 2% of the total external load. Sensitivity analysis showed the importance of accurate estimates of boundary nitrogen concentrations on the nitrogen levels on the shelf, especially at regions further away from the river influences. The boundary nitrogen concentrations impacted primary production less than nitrogen concent

Solid Rocket Booster Hydraulic Pump Port Cap Joint Load Testing

NASA Technical Reports Server (NTRS)

Gamwell, W. R.; Murphy, N. C.

2004-01-01

The solid rocket booster uses hydraulic pumps fabricated from cast C355 aluminum alloy, with 17-4 PH stainless steel pump port caps. Corrosion-resistant steel, MS51830 CA204L self-locking screw thread inserts are installed into C355 pump housings, with A286 stainless steel fasteners installed into the insert to secure the pump port cap to the housing. In the past, pump port cap fasteners were installed to a torque of 33 Nm (300 in-lb). However, the structural analyses used a significantly higher nut factor than indicated during tests conducted by Boeing Space Systems. When the torque values were reassessed using Boeing's nut factor, the fastener preload had a factor of safety of less than 1, with potential for overloading the joint. This paper describes how behavior was determined for a preloaded joint with a steel bolt threaded into steel inserts in aluminum parts. Finite element models were compared with test results. For all initial bolt preloads, bolt loads increased as external applied loads increased. For higher initial bolt preloads, less load was transferred into the bolt, due to external applied loading. Lower torque limits were established for pump port cap fasteners and additional limits were placed on insert axial deformation under operating conditions after seating the insert with an initial preload.

Novel instrument for characterizing comprehensive physical properties under multi-mechanical loads and multi-physical field coupling conditions

NASA Astrophysics Data System (ADS)

Liu, Changyi; Zhao, Hongwei; Ma, Zhichao; Qiao, Yuansen; Hong, Kun; Ren, Zhuang; Zhang, Jianhai; Pei, Yongmao; Ren, Luquan

2018-02-01

Functional materials represented by ferromagnetics and ferroelectrics are widely used in advanced sensor and precision actuation due to their special characterization under coupling interactions of complex loads and external physical fields. However, the conventional devices for material characterization can only provide a limited type of loads and physical fields and cannot simulate the actual service conditions of materials. A multi-field coupling instrument for characterization has been designed and implemented to overcome this barrier and measure the comprehensive physical properties under complex service conditions. The testing forms include tension, compression, bending, torsion, and fatigue in mechanical loads, as well as different external physical fields, including electric, magnetic, and thermal fields. In order to offer a variety of information to reveal mechanical damage or deformation forms, a series of measurement methods at the microscale are integrated with the instrument including an indentation unit and in situ microimaging module. Finally, several coupling experiments which cover all the loading and measurement functions of the instrument have been implemented. The results illustrate the functions and characteristics of the instrument and then reveal the variety in mechanical and electromagnetic properties of the piezoelectric transducer ceramic, TbDyFe alloy, and carbon fiber reinforced polymer under coupling conditions.

Work production of quantum rotor engines

NASA Astrophysics Data System (ADS)

Seah, Stella; Nimmrichter, Stefan; Scarani, Valerio

2018-04-01

We study the mechanical performance of quantum rotor heat engines in terms of common notions of work using two prototypical models: a mill driven by the heat flow from a hot to a cold mode, and a piston driven by the alternate heating and cooling of a single working mode. We evaluate the extractable work in terms of ergotropy, the kinetic energy associated to net directed rotation, as well as the intrinsic work based on the exerted torque under autonomous operation, and we compare them to the energy output for the case of an external dissipative load and for externally driven engine cycles. Our results connect work definitions from both physical and information-theoretical perspectives. In particular, we find that apart from signatures of angular momentum quantization, the ergotropy is consistent with the intuitive notion of work in the form of net directed motion. It also agrees with the energy output to an external load or agent under optimal conditions. This sets forth a consistent thermodynamical description of rotating quantum motors, flywheels, and clocks.

Bending strength model for internal spur gear teeth

NASA Technical Reports Server (NTRS)

Savage, Michael; Rubadeux, K. L.; Coe, H. H.

1995-01-01

Internal spur gear teeth are normally stronger than pinion teeth of the same pitch and face width since external teeth are smaller at the base. However, ring gears which are narrower have an unequal addendum or are made of a material with a lower strength than that of the meshing pinion may be loaded more critically in bending. In this study, a model for the bending strength of an internal gear tooth as a function of the applied load pressure angle is presented which is based on the inscribed Lewis constant strength parabolic beam. The bending model includes a stress concentration factor and an axial compression term which are extensions of the model for an external gear tooth. The geometry of the Lewis factor determination is presented, the iteration to determine the factor is described, and the bending strength J factor is compared to that of an external gear tooth. This strength model will assist optimal design efforts for unequal addendum gears and gears of mixed materials.

Electroencephalography Based Analysis of Working Memory Load and Affective Valence in an N-back Task with Emotional Stimuli

PubMed Central

Grissmann, Sebastian; Faller, Josef; Scharinger, Christian; Spüler, Martin; Gerjets, Peter

2017-01-01

Most brain-based measures of the electroencephalogram (EEG) are used in highly controlled lab environments and only focus on narrow mental states (e.g., working memory load). However, we assume that outside the lab complex multidimensional mental states are evoked. This could potentially create interference between EEG signatures used for identification of specific mental states. In this study, we aimed to investigate more realistic conditions and therefore induced a combination of working memory load and affective valence to reveal potential interferences in EEG measures. To induce changes in working memory load and affective valence, we used a paradigm which combines an N-back task (for working memory load manipulation) with a standard method to induce affect (affective pictures taken from the International Affective Picture System (IAPS) database). Subjective ratings showed that the experimental task was successful in inducing working memory load as well as affective valence. Additionally, performance measures were analyzed and it was found that behavioral performance decreased with increasing workload as well as negative valence, showing that affective valence can have an effect on cognitive processing. These findings are supported by changes in frontal theta and parietal alpha power, parameters used for measuring of working memory load in the EEG. However, these EEG measures are influenced by the negative valence condition as well and thereby show that detection of working memory load is sensitive to affective contexts. Unexpectedly, we did not find any effects for EEG measures typically used for affective valence detection (Frontal Alpha Asymmetry (FAA)). Therefore we assume that the FAA measure might not be usable if cognitive workload is induced simultaneously. We conclude that future studies should account for potential context-specifity of EEG measures. PMID:29311875

Electroencephalography Based Analysis of Working Memory Load and Affective Valence in an N-back Task with Emotional Stimuli.

PubMed

Grissmann, Sebastian; Faller, Josef; Scharinger, Christian; Spüler, Martin; Gerjets, Peter

2017-01-01

Most brain-based measures of the electroencephalogram (EEG) are used in highly controlled lab environments and only focus on narrow mental states (e.g., working memory load). However, we assume that outside the lab complex multidimensional mental states are evoked. This could potentially create interference between EEG signatures used for identification of specific mental states. In this study, we aimed to investigate more realistic conditions and therefore induced a combination of working memory load and affective valence to reveal potential interferences in EEG measures. To induce changes in working memory load and affective valence, we used a paradigm which combines an N-back task (for working memory load manipulation) with a standard method to induce affect (affective pictures taken from the International Affective Picture System (IAPS) database). Subjective ratings showed that the experimental task was successful in inducing working memory load as well as affective valence. Additionally, performance measures were analyzed and it was found that behavioral performance decreased with increasing workload as well as negative valence, showing that affective valence can have an effect on cognitive processing. These findings are supported by changes in frontal theta and parietal alpha power, parameters used for measuring of working memory load in the EEG. However, these EEG measures are influenced by the negative valence condition as well and thereby show that detection of working memory load is sensitive to affective contexts. Unexpectedly, we did not find any effects for EEG measures typically used for affective valence detection (Frontal Alpha Asymmetry (FAA)). Therefore we assume that the FAA measure might not be usable if cognitive workload is induced simultaneously. We conclude that future studies should account for potential context-specifity of EEG measures.

Microleakage at the Different Implant Abutment Interface: A Systematic Review

PubMed Central

Chowdhary, Ramesh; Kumari, Shail

2017-01-01

Introduction Presence of gap at the implant-abutment interface, leads to microleakage and accumulation of bacteria which can affect the success of dental implants. Aim To evaluate the sealing capability of different implant connections against microleakage. Materials and Methods In January 2017 an electronic search of literature was performed, in Medline, EBSCO host and Pubmed data base. The search was focused on ability of different implant connections in preventing microleakage. The related titles and abstracts available in English were screened, and the articles that fulfilled the inclusion criteria were selected for full text reading. Results In this systematic review, literature search initially resulted in 78 articles among which 30 articles only fulfilled the criteria for inclusion and were finally included in the review. Almost all the studies showed that there was some amount of microleakage at abutment implant interface. Microleakage was very less in Morse taper implants in comparison to other implant connections. Majority of studies showed less microleakage in static loading conditions and microleakage increases in dynamic loading conditions. Conclusion In this systematic review maximum studies showed that there was some amount of microleakage at abutment implant interface. External hexagon implants failed completely to prevent microleakage in both static and dynamic loading conditions of implants. Internal hexagon implants mainly internal conical (Morse taper) implants are very promising in case of static loading and also showed less microleakage in dynamic loading conditions. Torque recommended by manufacturer should be followed strictly to get a better seal at abutment implant interface. Zirconia abutments are more to microleakage than Titanium abutments and there use should be discouraged. Zirconia abutments should be only restricted to cases where there was very high demand of aesthetics. PMID:28764310

"External Conditions Affecting a Harmonious Family": Lessons Learned from a School-Based Parent Education Programme in Hong Kong

ERIC Educational Resources Information Center

Luk-Fong, Pattie Yuk Yee

2013-01-01

This article documents a parent education presentation on "External conditions affecting a harmonious family" within a school-based parent education programme in Hong Kong. The presentation adopted an eco-systems approach for understanding families and argued for the need to include the external conditions for a harmonious family as an…

Frequency effects on the stability of a journal bearing for periodic loading

NASA Technical Reports Server (NTRS)

Vijayaraghavan, D.; Brewe, D. E.

1992-01-01

The stability of a journal bearing is numerically predicted when an unidirectional periodic external load is applied. The analysis is performed using a cavitation algorithm, which mimics the JFO theory by accounting for the mass balance through the complete bearing. Hence, the history of the film is taken into consideration. The loading pattern is taken to be sinusoidal and the frequency of the load cycle is varied. The results are compared with the predictions using Reynolds boundary conditions for both film rupture and reformation. With such comparisons, the need for accurately predicting the cavitation regions for complex loading patterns is clearly demonstrated. For a particular frequency of loading, the effects of mass, amplitude of load vibration and frequency of journal speed are also investigated.

Angular-contact ball-bearing internal load estimation algorithm using runtime adaptive relaxation

NASA Astrophysics Data System (ADS)

Medina, H.; Mutu, R.

2017-07-01

An algorithm to estimate internal loads for single-row angular contact ball bearings due to externally applied thrust loads and high-operating speeds is presented. A new runtime adaptive relaxation procedure and blending function is proposed which ensures algorithm stability whilst also reducing the number of iterations needed to reach convergence, leading to an average reduction in computation time in excess of approximately 80%. The model is validated based on a 218 angular contact bearing and shows excellent agreement compared to published results.

Integration of Externally Carried Weapon Systems with Military Helicopters (L’Integration des Systemes d’Armes Transportes en Charge Externe sur les Helicopteres Militaires)

DTIC Science & Technology

1990-04-01

Np - Yaw to Roll Derivative (Yaw/Roll Coupling) Hr - Yaw to Yaw Rate Derivative (Yaw Damping) M - Pitch to Incidence Derivative (Incidence Stability) F...system is installed in the same configuration as used on the land based vehicle, simply by bolting-on to the limited number of available hard points...helicopters not originally designed to take external loads. The limited number of hard points on the fuselage structure leads to define supports of complex

Femoral Component External Rotation Affects Knee Biomechanics: A Computational Model of Posterior-stabilized TKA.

PubMed

Kia, Mohammad; Wright, Timothy M; Cross, Michael B; Mayman, David J; Pearle, Andrew D; Sculco, Peter K; Westrich, Geoffrey H; Imhauser, Carl W

2018-01-01

The correct amount of external rotation of the femoral component during TKA is controversial because the resulting changes in biomechanical knee function associated with varying degrees of femoral component rotation are not well understood. We addressed this question using a computational model, which allowed us to isolate the biomechanical impact of geometric factors including bony shapes, location of ligament insertions, and implant size across three different knees after posterior-stabilized (PS) TKA. Using a computational model of the tibiofemoral joint, we asked: (1) Does external rotation unload the medial collateral ligament (MCL) and what is the effect on lateral collateral ligament tension? (2) How does external rotation alter tibiofemoral contact loads and kinematics? (3) Does 3° external rotation relative to the posterior condylar axis align the component to the surgical transepicondylar axis (sTEA) and what anatomic factors of the femoral condyle explain variations in maximum MCL tension among knees? We incorporated a PS TKA into a previously developed computational knee model applied to three neutrally aligned, nonarthritic, male cadaveric knees. The computational knee model was previously shown to corroborate coupled motions and ligament loading patterns of the native knee through a range of flexion. Implant geometries were virtually installed using hip-to-ankle CT scans through measured resection and anterior referencing surgical techniques. Collateral ligament properties were standardized across each knee model by defining stiffness and slack lengths based on the healthy population. The femoral component was externally rotated from 0° to 9° relative to the posterior condylar axis in 3° increments. At each increment, the knee was flexed under 500 N compression from 0° to 90° simulating an intraoperative examination. The computational model predicted collateral ligament forces, compartmental contact forces, and tibiofemoral internal/external and varus-valgus rotation through the flexion range. The computational model predicted that femoral component external rotation relative to the posterior condylar axis unloads the MCL and the medial compartment; however, these effects were inconsistent from knee to knee. When the femoral component was externally rotated by 9° rather than 0° in knees one, two, and three, the maximum force carried by the MCL decreased a respective 55, 88, and 297 N; the medial contact forces decreased at most a respective 90, 190, and 570 N; external tibial rotation in early flexion increased by a respective 4.6°, 1.1°, and 3.3°; and varus angulation of the tibia relative to the femur in late flexion increased by 8.4°, 8.0°, and 7.9°, respectively. With 3° of femoral component external rotation relative to the posterior condylar axis, the femoral component was still externally rotated by up to 2.7° relative to the sTEA in these three neutrally aligned knees. Variations in MCL force from knee to knee with 3° of femoral component external rotation were related to the ratio of the distances from the femoral insertion of the MCL to the posterior and distal cuts of the implant; the closer this ratio was to 1, the more uniform were the MCL tensions from 0° to 90° flexion. A larger ratio of distances from the femoral insertion of the MCL to the posterior and distal cuts may cause clinically relevant increases in both MCL tension and compartmental contact forces. To obtain more consistent ligament tensions through flexion, it may be important to locate the posterior and distal aspects of the femoral component with respect to the proximal insertion of the MCL such that a ratio of 1 is achieved.

A Comparison of Load-Velocity and Load-Power Relationships Between Well-Trained Young and Middle-Aged Males During Three Popular Resistance Exercises.

PubMed

Fernandes, John F T; Lamb, Kevin L; Twist, Craig

2018-05-01

Fernandes, JFT, Lamb, KL, and Twist, C. A comparison of load-velocity and load-power relationships between well-trained young and middle-aged males during 3 popular resistance exercises. J Strength Cond Res 32(5): 1440-1447, 2018-This study examined the load-velocity and load-power relationships among 20 young (age 21.0 ± 1.6 years) and 20 middle-aged (age 42.6 ± 6.7 years) resistance-trained males. Participants performed 3 repetitions of bench press, squat, and bent-over-row across a range of loads corresponding to 20-80% of 1 repetition maximum (1RM). Analysis revealed effects (p < 0.05) of group and load × group on barbell velocity for all 3 exercises, and interaction effects on power for squat and bent-over-row (p < 0.05). For bench press and bent-over-row, the young group produced higher barbell velocities, with the magnitude of the differences decreasing as load increased (ES; effect size 0.0-1.7 and 1.0-2.0, respectively). Squat velocity was higher in the young group than the middle-aged group (ES 1.0-1.7) across all loads, as was power for each exercise (ES 1.0-2.3). For all 3 exercises, both velocity and 1RM were correlated with optimal power in the middle-aged group (r = 0.613-0.825, p < 0.05), but only 1RM was correlated with optimal power (r = 0.708-0.867, p < 0.05) in the young group. These findings indicate that despite their resistance training, middle-aged males were unable to achieve velocities at low external loads and power outputs as high as the young males across a range of external resistances. Moreover, the strong correlations between 1RM and velocity with optimal power suggest that middle-aged males would benefit from training methods which maximize these adaptations.

Structural Assessment of Externally Strengthened Bridge Deck Panels

NASA Astrophysics Data System (ADS)

Sim, Jongsung; Oh, Hongseob; Meyer, Christian

2006-03-01

Deteriorated concrete bridge decks are strengthened with external bonding technique using either steel plate or various FRPs to enhance the decreased load carrying capacity and serviceability. But the failure characteristics of bridge decks strengthened with various materials can be changed according to mechanical properties of strengthening materials or strengthening scheme as well as the strengthening amount. In this paper, strengthening effect of deck strengthened with carbon fiber sheets, glass fiber sheets or steel plates is compared. And the theoretical load carrying capacity are evaluated using yield line theory and punching shear model properly modified for the strengthened RC member. The panels strengthened with sheet type FRP materials failed more often in a ductile mode, indicating that the failure developed after the rebar yielded.

Bioconversion of cellulose into electrical energy in microbial fuel cells

NASA Astrophysics Data System (ADS)

Rismani-Yazdi, Hamid

In microbial fuel cells (MFCs), bacteria generate electricity by mediating the oxidation of organic compounds and transferring the resulting electrons to an anode electrode. The first objective of this study was to test the possibility of generating electricity with rumen microorganisms as biocatalysts and cellulose as the electron donor in two-compartment MFCs. Maximum power density reached 55 mW/m2 (1.5 mA, 313 mV) with cellulose as the electron donor. Cellulose hydrolysis and electrode reduction were shown to support the production of current. The electrical current was sustained for over two months with periodic cellulose addition. Clarified rumen fluid and a soluble carbohydrate mixture, serving as the electron donors, could also sustain power output. The second objective was to analyze the composition of the bacterial communities enriched in the cellulose-fed MFCs. Denaturing gradient gel electrophoresis of PCR amplified 16S rRNA genes revealed that the microbial communities differed when different substrates were used in the MFCs. The anode-attached and the suspended consortia were shown to be different within the same MFC. Cloning and analysis of 16S rRNA gene sequences indicated that the most predominant bacteria in the anode-attached consortia were related to Clostridium spp., while Comamonas spp. was abundant in the suspended consortia. The external resistance affects the characteristic outputs of MFCs by controlling the flow of electrons from the anode to the cathode. The third objective of this study was to determine the effect of various external resistances on power output and coulombic efficiency of cellulose-fed MFCs. Four external resistances (20, 249, 480, and 1000 ohms) were tested with a systematic approach of operating parallel MFCs independently at constant circuit loads for three months. A maximum power density of 66 mWm-2 was achieved by MFCs with 20 ohms circuit load, while MFCs with 249, 480 and1000 ohms external resistances produced 57.5, 53 and 47 mWm-2, respectively. The anode potential varied under the different circuit loads employed. Higher coulombic efficiencies were achieved in MFCs with lower external resistance. The effect of different external resistances on the bacterial diversity and metabolism in cellulose-fed MFCs was investigated as the fourth objective. DGGE analysis of partial 16S rRNA genes showed clear differences between the planktonic and the anode-attached populations at various external resistances. Cellulose degradation was complete (< 0.1% residual), and there were no discernible differences among the MFCs. HPLC analysis of short chain fatty acids (SCFA) revealed that anaerobic degradation of cellulose was accompanied by production of acetic, propionic, butyric, isobutyric, valeric, isovaleric, and lactic acids, with acetic acid being predominant. The profile of metabolites was different among the MFCs. The concentrations of SCFA were higher in MFCs with larger external resistance. High levels of SCFA indicated that fermentative metabolism dominated over anaerobic respiration, resulting in relatively low coulombic efficiencies. The accumulation of SCFA at higher circuit resistances corresponded to lower power outputs. Methanogenesis shifts the flow of electrons available from the substrate away from electricity generation in MFCs. The fifth objective of this research was to assess the influence of methane formation on the performance of cellulose-fed MFCs under long-term operation. A maximum volumetric power density of 3.5 W m-3 was achieved in R20O MFCs, which was three times greater than that obtained with R100O MFCs (1.03 W m-3). The diversity of methanogens in cellulose-fed MFCs was also characterized. It was shown that the suppression of methanogenesis was accompanied by a decrease in the diversity of methanogens and changes in the concentration of SCFA, as revealed by DGGE analysis of PCR-amplified 16S rRNA genes and HPLC analysis, respectively. Analysis of partial 16S rRNA gene Sequences indicated that the most predominant methanogens were related to the family Methanobacteriaceae . The results demonstrate that electricity can be generated from cellulose by exploiting rumen microorganisms as biocatalysts. Results suggest that oxidation of metabolites with the anode as an electron sink was a rate limiting step in the conversion of cellulose to electricity in MFCs. This study also demonstrates that the size of external resistance significantly affects the bacterial diversity and characteristic output of MFCs. Thus the external resistance may be a useful tool to control microbial communities and consequently enhance performance of MFCs. Furthermore, this study shows that methanogenesis competes with electricity generation at the early stages of MFC operation but operating conditions suppress methanogenic activity over time. An improved understanding of the microbial communities, interspecies interactions and processes involved in electricity generation is essential to effectively design and control cellulose-fed MFCs for enhanced performance. In addition, technical and biological optimization is needed to maximize power output of these systems.

Experimental study of plastic responses of pipe elbows

DOE Office of Scientific and Technical Information (OSTI.GOV)

Greenstreet, W.L.

Load-deflection responses were determined experimentally for sixteen 152.4-mm (6-in.) (nominal) commercial carbon steel pipe elbows and four 152.4-mm (6-in.) stainless steel elbows. Each specimen was loaded with an external force of sufficient magnitude to produce predominantly plastic response. The influences of bend radius and wall thickness were studied, as well as the effect of internal prssure on load-deflection behavior. Comparisons of results from stainless steel and from carbon steel elbows indicate differences in responses attributable to material differences. The results were interpreted in terms of limit analysis concepts, and collapse loads were determined. Trends given by the collapse loads aremore » identified and discussed.« less

Effects of adsorptive properties of biofilter packing materials on toluene removal.

PubMed

Oh, Dong Ik; Song, Jihyeon; Hwang, Sun Jin; Kim, Jae Young

2009-10-15

Various adsorptive materials, including granular activated carbon (GAC) and ground tire rubber (GTR), were mixed with compost in biofilters used for treating gaseous toluene, and the effects of the mixtures on the stability of biofilter performance were investigated. A transient loading test demonstrated that a sudden increase in inlet toluene loading was effectively attenuated in the compost/GAC biofilter, which was the most significant advantage of adding adsorptive materials to the biofilter packing media. Under steady conditions with inlet toluene loading rates of 18.8 and 37.5 g/m(3)/h, both the compost and the compost/GAC biofilters achieved overall toluene removal efficiencies greater than 99%. In the compost/GAC mixture, however, biodegradation activity declined as the GAC mass fraction increased. Because of the low water-holding capacity of GTR, the compost/ground tire mixture did not show a significant improvement in toluene removal efficiency throughout the entire operational period. Furthermore, nitrogen limitations affected system performance in all the biofilters, but an external nitrogen supply resulted in the recovery of the toluene removal efficiency only in the compost biofilter during the test periods. Consequently, the introduction of excessive adsorptive materials was unfavorable for long-term performance, suggesting that the mass ratio of the adsorptive materials in such mixtures should be carefully selected to achieve high and steady biofilter performance.

Changes in postural sway as a consequence of wearing a military backpack.

PubMed

Heller, Michelle F; Challis, John H; Sharkey, Neil A

2009-07-01

Military personnel are often required to carry all of their personal supplies and equipment for long distances during both training and combat situations, creating many biomechanical and postural challenges for these individuals. In addition to other problems such as generalized fatigue and the development of stress fractures, significant external loads may also affect a soldier's postural sway. The purpose of this study was to assess changes in postural sway as a consequence of wearing a military backpack in females. Forty-three female subjects between the ages of 18 and 25 volunteered to participate. There were two conditions: unloaded and while wearing an 18.1 kg military backpack. Each subject stood with two feet on a force platform for 30s under both conditions while center of pressure (COP) data were collected. COP path length increased 64%, medial-lateral excursion increased 131%, anterior-posterior excursion increased 54%, and COP area increased 229% with addition of the backpack (p<0.0001 for all of these measures). These data show that wearing 18.1 kg of external weight in a military backpack increases the postural sway of females, which may in turn increase the likelihood of falls and injury.

Fuelling decisions in migratory birds: geomagnetic cues override the seasonal effect.

PubMed

Kullberg, Cecilia; Henshaw, Ian; Jakobsson, Sven; Johansson, Patrik; Fransson, Thord

2007-09-07

Recent evaluations of both temporal and spatial precision in bird migration have called for external cues in addition to the inherited programme defining the migratory journey in terms of direction, distance and fuelling behaviour along the route. We used juvenile European robins (Erithacus rubecula) to study whether geomagnetic cues affect fuel deposition in a medium-distance migrant by simulating a migratory journey from southeast Sweden to the wintering area in southern Spain. In the late phase of the onset of autumn migration, robins exposed to the magnetic treatment attained a lower fuel load than control birds exposed to the ambient magnetic field of southeast Sweden. In contrast, robins captured in the early phase of the onset of autumn migration all showed low fuel deposition irrespective of experimental treatment. These results are, as expected, the inverse of what we have found in similar studies in a long-distance migrant, the thrush nightingale (Luscinia luscinia), indicating that the reaction in terms of fuelling behaviour to a simulated southward migration varies depending on the relevance for the species. Furthermore, we suggest that information from the geomagnetic field act as an important external cue overriding the seasonal effect on fuelling behaviour in migratory birds.

External Catalyst Breakup Phenomena

DTIC Science & Technology

1976-06-01

catalyst particle can cause high internal pressures which result in particle destruction. Analytical results suggest rhat erosion effects from solid...mechanisms. * Pressure Forces. High G loadings and bed pressure drops should be avoided. Bed pre-loads should be kept at a minimum value. Thruster...5.2.7.1 Failure Theories ............................ 243 5.2.7.2 Maximum Tension Stress Criterion ............ 244 5.2.7.3 Distortion Energy Approach

Structural Turnbuckle Bears Compressive or Tensile Loads

NASA Technical Reports Server (NTRS)

Bateman, W. A.; Lang, C. H.

1985-01-01

Column length adjuster based on turnbuckle principle. Device consists of internally and externally threaded bushing, threaded housing and threaded rod. Housing attached to one part and threaded rod attached to other part of structure. Turning double threaded bushing contracts or extends rod in relation to housing. Once adjusted, bushing secured with jamnuts. Device used for axially loaded members requiring length adjustment during installation.

Monitoring Hitting Load in Tennis Using Inertial Sensors and Machine Learning.

PubMed

Whiteside, David; Cant, Olivia; Connolly, Molly; Reid, Machar

2017-10-01

Quantifying external workload is fundamental to training prescription in sport. In tennis, global positioning data are imprecise and fail to capture hitting loads. The current gold standard (manual notation) is time intensive and often not possible given players' heavy travel schedules. To develop an automated stroke-classification system to help quantify hitting load in tennis. Nineteen athletes wore an inertial measurement unit (IMU) on their wrist during 66 video-recorded training sessions. Video footage was manually notated such that known shot type (serve, rally forehand, slice forehand, forehand volley, rally backhand, slice backhand, backhand volley, smash, or false positive) was associated with the corresponding IMU data for 28,582 shots. Six types of machine-learning models were then constructed to classify true shot type from the IMU signals. Across 10-fold cross-validation, a cubic-kernel support vector machine classified binned shots (overhead, forehand, or backhand) with an accuracy of 97.4%. A second cubic-kernel support vector machine achieved 93.2% accuracy when classifying all 9 shot types. With a view to monitoring external load, the combination of miniature inertial sensors and machine learning offers a practical and automated method of quantifying shot counts and discriminating shot types in elite tennis players.

Investigation on the fiber based approach to estimate the axial load carrying capacity of the circular concrete filled steel tube (CFST)

NASA Astrophysics Data System (ADS)

Piscesa, B.; Attard, M. M.; Suprobo, P.; Samani, A. K.

2017-11-01

External confining devices are often used to enhance the strength and ductility of reinforced concrete columns. Among the available external confining devices, steel tube is one of the most widely used in construction. However, steel tube has some drawbacks such as local buckling which needs to be considered when estimating the axial load carrying capacity of the concrete-filled-steel-tube (CFST) column. To tackle this problem in design, Eurocode 4 provided guidelines to estimate the effective yield strength of the steel tube material. To study the behavior of CFST column, in this paper, a non-linear analysis using a fiber-based approach was conducted. The use of the fiber-based approach allows the engineers to predict not only the axial load carrying capacity but also the complete load-deformation curve of the CFST columns for a known confining pressure. In the proposed fiber-based approach, an inverse analysis is used to estimate the constant confining pressure similar to design-oriented models. This paper also presents comparisons between the fiber-based approach model with the experimental results and the 3D non-linear finite element analysis.

Influence of abutment screw preload on stress distribution in marginal bone.

PubMed

Khraisat, Ameen

2012-01-01

Changes in an implant assembly after abutment connection might possibly cause deformation in the implant/abutment joint and even in the marginal bone. The aim of this study was to evaluate the influence of abutment screw preload through the implant collar on marginal bone stress without external load application. Models of three implant parts made of titanium (implant, abutment, and abutment screw) and cortical bone were built and positioned with computer-aided design software. Meshing and generation of boundary conditions, loads, and interactions were performed. Each part was meshed independently. The sole load applied to the model was a torque of 32 Ncm on the abutment screw about its axis of rotation. The implant collar was deformed axially after the screw was tightened (3 μm). This deformation resulted in 60 MPa of stress in the marginal bone. Moreover, pressure on the marginal bone in a radial direction was observed. It can be concluded that, without any external load application, abutment screw preload exerts stresses on the implant collar and the marginal bone. These findings should help guide the development of new implant/abutment joint designs that exert less stress on the marginal bone.

A Spine Loading Model of Women in the Military

DTIC Science & Technology

1996-10-01

latissimuss dorsi, posterior abdominal internal obliques, rectus abdomini and the abdominal external obliques (5,19). MVC exertions consisting of...Women tend to possess greater hip breadth and narrower abdominal depth than men (9). The sacroiliac joint is positioned several centimeters anteriorly...internal obliques, external obliques, rectus abdomini, and psoas major. The sizes and area centriods are also quantified for the vertebral body and the

76 FR 4847 - Hazardous Materials: Safety Requirements for External Product Piping on Cargo Tanks Transporting...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-27

... limit of one liter or less in each pipe, but did not propose a specific method for achieving this... purged, we are proposing to allow a residue quantity of no more than one liter (0.26 gallon or 33 ounces... wetlines to the one liter residue level. For example, an operator may elect to design external loading...

Development of a Pressure Box to Evaluate Reusable-Launch-Vehicle Cryogenic-Tank Panels

NASA Technical Reports Server (NTRS)

Ambur, Damodar R.; Sikora, Joseph; Maguire, James F.; Winn, Peter M.

1996-01-01

A cryogenic pressure-box test machine has been designed and is being developed to test full-scale reusable-launch-vehicle cryogenic-tank panels. This machine is equipped with an internal pressurization system, a cryogenic cooling system, and a heating system to simulate the mechanical and thermal loading conditions that are representative of a reusable-launch-vehicle mission profile. The cryogenic cooling system uses liquid helium and liquid nitrogen to simulate liquid hydrogen and liquid oxygen tank internal temperatures. A quartz lamp heating system is used for heating the external surface of the test panels to simulate cryogenic-tank external surface temperatures during re-entry of the launch vehicle. The pressurization system uses gaseous helium and is designed to be controlled independently of the cooling system. The tensile loads in the axial direction of the test panel are simulated by means of hydraulic actuators and a load control system. The hoop loads in the test panel are reacted by load-calibrated turnbuckles attached to the skin and frame elements of the test panel. The load distribution in the skin and frames can be adjusted to correspond to the tank structure by using these turnbuckles. The seal between the test panel and the cryogenic pressure box is made from a reinforced Teflon material which can withstand pressures greater than 52 psig at cryogenic temperatures. Analytical results and tests on prototype test components indicate that most of the cryogenic-tank loading conditions that occur in flight can be simulated in the cryogenic pressure-box test machine.

The influence of gender-specific loading patterns of the stop-jump task on anterior cruciate ligament strain.

PubMed

Weinhold, Paul S; Stewart, Jason-Dennis N; Liu, Hsin-Yi; Lin, Cheng-Feng; Garrett, William E; Yu, Bing

2007-08-01

Studies have shown that women are at higher risk of sustaining noncontact anterior cruciate ligament (ACL) injuries in specific sports. Recent gait studies of athletic tasks have documented that gender differences in knee movement, muscle activation, and external loading patterns exist. The objective of this study was to determine in a knee cadaver model if application of female-specific loading and movement patterns characterised in vivo for a stop-jump task cause higher ACL strains than male patterns. Gender-specific loading patterns of the landing phase of the vertical stop-jump task were applied to seven cadaver knees using published kinetic/kinematic results for recreational athletes. Loads applied consecutively included: tibial compression, quadriceps, hamstrings, external posterior tibial shear, and tibial torque. Knee flexion was fixed based on the kinematic data. Strain of the ACL was monitored by means of a differential variable reluctance transducer installed on the anterior-medial bundle of the ACL. The ACL strain was significantly increased (P<0.05) for the female loading pattern relative to the male loading pattern after the posterior tibial shear force was applied, and showed a similar trend (P=0.1) to be increased after the final tibial torque was applied. This study suggests that female motor control strategies used during the stop-jump task may place higher strains on the ACL than male strategies, thus putting females at greater risk of ACL injury. We believe these results suggest the potential effectiveness of using training programs to modify motor control strategies and thus modify the risk of injury.

The Association Between Callous-Unemotional Traits, Externalizing Problems, and Gender in Predicting Cognitive and Affective Morality Judgments in Adolescence.

PubMed

Fragkaki, Iro; Cima, Maaike; Meesters, Cor

2016-09-01

Morality deficits have been linked to callous-unemotional traits and externalizing problems in response to moral dilemmas, but these associations are still obscure in response to antisocial acts in adolescence. Limited evidence on young boys suggested that callous-unemotional traits and externalizing problems were associated with affective but not cognitive morality judgments. The present study investigated these associations in a community sample of 277 adolescents (M age  = 15.35, 64 % females). Adolescents with high callous-unemotional traits showed deficits in affective but not cognitive morality, indicating that they can identify the appropriate moral emotions in others, but experience deviant moral emotions when imagining themselves committing antisocial acts. Externalizing problems and male gender were also strongly related to deficits in affective morality, but they had smaller associations with deficits in cognitive morality too. Implications for treatment and the justice system are discussed.

Minimum distraction gap: how much ankle joint space is enough in ankle distraction arthroplasty?

PubMed

Fragomen, Austin T; McCoy, Thomas H; Meyers, Kathleen N; Rozbruch, S Robert

2014-02-01

The success of ankle distraction arthroplasty relies on the separation of the tibiotalar articular surfaces. The purpose of this study was to find the minimum distraction gap needed to ensure that the tibiotalar joint surfaces would not contact each other with full weight-bearing while under distraction. Circular external fixators were mounted to nine cadaver ankle specimens. Each specimen was then placed into a custom-designed load chamber. Loads of 0, 350, and 700N were applied to the specimen. Radiographic joint space was measured and joint contact pressure was monitored under each load. The external fixator was then sequentially distracted, and the radiographic joint space was measured under the three different loads. The experiment was stopped when there was no joint contact under 700N of load. The radiographic joint space was measured and the initial (undistracted) radiographic joint space was subtracted from it yielding the distraction gap. The minimum distraction gap (mDG) that would provide total unloading was calculated. The average mDG was 2.4 mm (range, 1.6 to 4.0 mm) at 700N of load, 4.4 mm (range, 3.7 to 5.8 mm) at 350N of load, and 4.9 mm (range, 3.7 to 7.0 mm) at 0N of load. These results suggest that if the radiographic joint space of on a standing X-ray of an ankle undergoing distraction arthroplasty shows a minimum of 5.8 mm of DG, then there will be no contact between joint surfaces during full weight-bearing. Therefore, 5 mm of radiographic joint space, as recommended historically, may not be adequate to prevent contact of the articular surfaces during weight-bearing.

Gender Dimorphic ACL Strain In Response to Combined Dynamic 3D Knee Joint Loading: Implications for ACL Injury Risk

PubMed Central

Mizuno, Kiyonori; Andrish, Jack T.; van den Bogert, Antonie J.; McLean, Scott G.

2009-01-01

While gender-based differences in knee joint anatomies/laxities are well documented, the potential for them to precipitate gender-dimorphic ACL loading and resultant injury risk has not been considered. To this end, we generated gender-specific models of ACL strain as a function of any six degrees of freedom (6DOF) knee joint load state via a combined cadaveric and analytical approach. Continuously varying joint forces and torques were applied to five male and five female cadaveric specimens and recorded along with synchronous knee flexion and ACL strain data. All data (~10,000 samples) were submitted to specimen-specific regression analyses, affording ACL strain predictions as a function of the combined 6 DOF knee loads. Following individual model verifications, generalized gender-specific models were generated and subjected to 6 DOF external load scenarios consistent with both a clinical examination and a dynamic sports maneuver. The ensuing model-based strain predictions were subsequently examined for gender-based discrepancies. Male and female specimen specific models predicted ACL strain within 0.51% ± 0.10% and 0.52% ± 0.07% of the measured data respectively, and explained more than 75% of the associated variance in each case. Predicted female ACL strains were also significantly larger than respective male values for both of simulated 6 DOF load scenarios. Outcomes suggest that the female ACL will rupture in response to comparatively smaller external load applications. Future work must address the underlying anatomical/laxity contributions to knee joint mechanical and resultant ACL loading, ultimately affording prevention strategies that may cater to individual joint vulnerabilities. PMID:19464897

Short-term effect of antibiotics on human gut microbiota.

PubMed

Panda, Suchita; El khader, Ismail; Casellas, Francesc; López Vivancos, Josefa; García Cors, Montserrat; Santiago, Alba; Cuenca, Silvia; Guarner, Francisco; Manichanh, Chaysavanh

2014-01-01

From birth onwards, the human gut microbiota rapidly increases in diversity and reaches an adult-like stage at three years of age. After this age, the composition may fluctuate in response to external factors such as antibiotics. Previous studies have shown that resilience is not complete months after cessation of the antibiotic intake. However, little is known about the short-term effects of antibiotic intake on the gut microbial community. Here we examined the load and composition of the fecal microbiota immediately after treatment in 21 patients, who received broad-spectrum antibiotics such as fluoroquinolones and β-lactams. A fecal sample was collected from all participants before treatment and one week after for microbial load and community composition analyses by quantitative PCR and pyrosequencing of the 16S rRNA gene, respectively. Fluoroquinolones and β-lactams significantly decreased microbial diversity by 25% and reduced the core phylogenetic microbiota from 29 to 12 taxa. However, at the phylum level, these antibiotics increased the Bacteroidetes/Firmicutes ratio (p = 0.0007, FDR = 0.002). At the species level, our findings unexpectedly revealed that both antibiotic types increased the proportion of several unknown taxa belonging to the Bacteroides genus, a Gram-negative group of bacteria (p = 0.0003, FDR<0.016). Furthermore, the average microbial load was affected by the treatment. Indeed, the β-lactams increased it significantly by two-fold (p = 0.04). The maintenance of or possible increase detected in microbial load and the selection of Gram-negative over Gram-positive bacteria breaks the idea generally held about the effect of broad-spectrum antibiotics on gut microbiota.

Muscle-Specific Effective Mechanical Advantage and Joint Impulse in Weightlifting.

PubMed

Kipp, Kristof; Harris, Chad

2017-07-01

Kipp, K, and Harris, C. Muscle-specific effective mechanical advantage and joint impulse in weightlifting. J Strength Cond Res 31(7): 1905-1910, 2017-Lifting greater loads during weightlifting exercises may theoretically be achieved through increasing the magnitudes of net joint impulses or manipulating the joints' effective mechanical advantage (EMA). The purpose of this study was to investigate muscle-specific EMA and joint impulse as well as impulse-momentum characteristics of the lifter-barbell system across a range of external loads during the execution of the clean. Collegiate-level weightlifters performed submaximal cleans at 65, 75, and 85% of their 1-repetition maximum (1-RM), whereas data from a motion analysis system and a force plate were used to calculate lifter-barbell system impulse and velocity, as well as net extensor impulse generated at the hip, knee, and ankle joints and the EMA of the gluteus maximus, hamstrings, quadriceps, and triceps surae muscles. The results indicated that the lifter-barbell system impulse did not change as load increased, whereas the velocity of the lifter-barbell system decreased with greater load. In addition, the net extensor impulse at all joints increased as load increased. The EMA of all muscles did not, however, change as load increased. The load-dependent effects on the impulse-velocity characteristics of the lifter-barbell system may reflect musculoskeletal force-velocity behaviors, and may further indicate that the weightlifting performance is limited by the magnitude of ground reaction force impulse. In turn, the load-dependent effects observed at the joint level indicated that lifting greater loads were due to greater net extensor impulses generated at the joints of the lower extremity and not greater EMAs of the respective extensor muscles. In combination, these results suggest that lifting greater external loads during the clean is due to the ability to generate large extensor joint impulses, rather than manipulate EMA.

An apparatus for altering the mechanical load of the respiratory system.

PubMed

Younes, M; Bilan, D; Jung, D; Kroker, H

1987-06-01

We describe an apparatus for altering the mechanical load against which the respiratory muscles operate in humans. A closed system incorporates a rolling seal spirometer. The spirometer piston shaft is coupled to a fast-responding linear actuator that develops force in proportion to desired command signals. The command signal may be flow (resistive loading or unloading), volume (elastic loading or unloading), constant voltage (continuous positive or negative pressure), or any external function. Combinations of loads can be applied. Logic circuits permit application of the load at specific times during the respiratory cycle, and the magnitude of the loads is continuously adjustable. Maximum pressure output is +/- 20 cmH2O. The apparatus permits loading or unloading over a range of ventilation extending from resting levels to those observed during high levels of exercise (over 100 l/min). In response to a square-wave input, pressure rises exponentially with a time constant of 20 ms.

Locomotor and Heart Rate Responses of Floaters During Small-Sided Games in Elite Soccer Players: Effect of Pitch Size and Inclusion of Goalkeepers.

PubMed

Lacome, Mathieu; Simpson, Ben M; Cholley, Yannick; Buchheit, Martin

2018-05-01

To (1) compare the locomotor and heart rate responses between floaters and regular players during both small and large small-sided games (SSGs) and (2) examine whether the type of game (ie, game simulation [GS] vs possession game [PO]) affects the magnitude of the difference between floaters and regular players. Data were collected in 41 players belonging to an elite French football team during 3 consecutive seasons (2014-2017). A 5-Hz global positionning system was used to collect all training data, with the Athletic Data Innovation analyzer (v5.4.1.514) used to derive total distance (m), high-speed distance (>14.4 km·h -1 , m), and external mechanical load (MechL, a.u.). All SSGs included exclusively 1 floater and were divided into 2 main categories, according to the participation of goalkeepers (GS) or not (PO) and then further divided into small and large (>100 m 2 per player) SSGs based on the area per player ratio. Locomotor activity and MechL performed were likely-to-most likely lower (moderate to large magnitude) in floaters compared with regular players, whereas differences in heart rate responses were unclear to possibly higher (small) in floaters. The magnitude of the difference in locomotor activity and MechL between floaters and regular players was substantially greater during GS compared with PO. Compared with regular players, floaters present decreased external load (both locomotor and MechL) despite unclear to possibly slightly higher heart rate responses during SSGs. Moreover, the responses of floaters compared with regular players are not consistent across different sizes of SSGs, with greater differences during GS than PO.

Visuospatial referents facilitate the learning and transfer of mathematical operations: extending the role of the angular gyrus.

PubMed

Pyke, Aryn; Betts, Shawn; Fincham, Jon M; Anderson, John R

2015-03-01

Different external representations for learning and solving mathematical operations may affect learning and transfer. To explore the effects of learning representations, learners were each introduced to two new operations (b↑n and b↓n) via either formulas or graphical representations. Both groups became adept at solving regular (trained) problems. During transfer, no external formulas or graphs were present; however, graph learners' knowledge could allow them to mentally associate problem expressions with visuospatial referents. The angular gyrus (AG) has recently been hypothesized to map problems to mental referents (e.g., symbolic answers; Grabner, Ansari, Koschutnig, Reishofer, & Ebner Human Brain Mapping, 34, 1013-1024, 2013), and we sought to test this hypothesis for visuospatial referents. To determine whether the AG and other math (horizontal intraparietal sulcus) and visuospatial (fusiform and posterior superior parietal lobule [PSPL]) regions were implicated in processing visuospatial mental referents, we included two types of transfer problems, computational and relational, which differed in referential load (one graph vs. two). During solving, the activations in AG, PSPL, and fusiform reflected the referential load manipulation among graph but not formula learners. Furthermore, the AG was more active among graph learners overall, which is consistent with its hypothesized referential role. Behavioral performance was comparable across the groups on computational transfer problems, which could be solved in a way that incorporated learners' respective procedures for regular problems. However, graph learners were more successful on relational transfer problems, which assessed their understanding of the relations between pairs of similar problems within and across operations. On such problems, their behavioral performance correlated with activation in the AG, fusiform, and a relational processing region (BA 10).

Sulfate-chloride exchange by lobster hepatopancreas is regulated by pH-sensitive modifier sites

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cattey, M.A.; Ahearn, G.A.; Gerencser, G.A.

1991-03-15

{sup 35}SO{sub 4}{sup 2{minus}} uptake by Atlantic lobster (Homarus americanus) hepatopancreatic epithelial brush border membrane vesicles (BBMV) was stimulated by internal Cl{sup {minus}}, but not internal HCO{sub 3}{sup {minus}}, or external Na{sup +}. Sulfate-chloride exchange was stimulated by inside positive, and inhibited by inside negative, trans-membrane K diffusion potentials. {sup 35}SO{sub 4}{sup 2{minus}}-Cl{sup {minus}} exchange was strongly inhibited by 4,4{prime} diisothiocyanostilbene-2,2{prime}-disulfonic acid (DIDS), 4-acetamido-4{prime}-isotheocynaostilbene-2,2{prime}-disulfonic acid, (SITS), and thiosulfate. Chloride, bicarbonate, furosamide, and bumetanide slightly, yet significantly, cis-inhibited {sup 35}SO{sub 4}{sup 2{minus}}-Cl{sup {minus}} exchange. Altering bilateral pH from 8.0 to 5.4 stimulated {sup 35}SO{sub 4}{sup 2{minus}}-Cl{sup {minus}} exchange when vesicles weremore » loaded with Cl{sup {minus}}, but reduced bilateral pH alone or the presence of pH gradients did not affect {sup 35}SO{sub 4}{sup 2{minus}} transport in the absence of internal Cl{sup {minus}}. {sup 36}Cl uptake into SO{sub 4}{sup 2{minus}}-loaded BBMV was stimulated by an internal negative membrane potential and inhibited when the interior was electrically positive. A model is proposed which suggests that SO{sub 4}{sup 2{minus}}-Cl{sup {minus}} exchange is regulated by internal and external pH-sensitive modifier sites on the anion antiporter and by coupling to the electrogenic 2 Na{sup +}/1 H{sup +} antiporter and by coupling to the electrogenic 2 Na{sup +}/1 H{sup +} antiporter on the same membrane.« less

Altered control strategy between leading and trailing leg increases knee adduction moment in the elderly while descending stairs.

PubMed

Karamanidis, Kiros; Arampatzis, Adamantios

2011-02-24

The aim of the study was to examine the external knee adduction moments in a group of older and younger adults while descending stairs and thus the possibility of an increased risk of knee osteoarthritis due to altered knee joint loading in the elderly. Twenty-seven older and 16 younger adults descended a purpose-built staircase. A motion capture system and a force plate were used to determine the subjects' 3D kinematics and ground reaction forces (GRF) during locomotion. Calculation of the leg kinematics and kinetics was done by means of a rigid, three-segment, 3D leg model. In the initial portion of the support phase, older adults showed a more medio-posterior GRF vector relative to the ankle joint, leading to lower ankle joint moments (P<0.05). At the knee, the older adults demonstrated a more medio-posterior directed GRF vector, increasing in knee flexion and adduction in the second part of the single support phase (P<0.05). Further, GRF magnitude was lower in the initial and higher in the mid-portions of the support phase for the elderly (P<0.05). The results show that older adults descend stairs by using the trailing leg before the initiation of the double support phase more compared to the younger ones. The consequence of this altered control strategy while stepping down is a more medially directed GRF vector increasing the magnitude of external knee adduction moment in the elderly. The observed changes between leading and trailing leg in the elderly may cause a redistribution of the mechanical load at the tibiofemoral joint, affecting the initiation and progression of knee osteoarthritis in the elderly. Copyright © 2010 Elsevier Ltd. All rights reserved.

External Hand Forces Exerted by Long-Term Care Staff to Push Floor-Based Lifts: Effects of Flooring System and Resident Weight.

PubMed

Lachance, Chantelle C; Korall, Alexandra M B; Russell, Colin M; Feldman, Fabio; Robinovitch, Stephen N; Mackey, Dawn C

2016-09-01

The aim of this study was to investigate the effects of flooring type and resident weight on external hand forces required to push floor-based lifts in long-term care (LTC). Novel compliant flooring is designed to reduce fall-related injuries among LTC residents but may increase forces required for staff to perform pushing tasks. A motorized lift may offset the effect of flooring on push forces. Fourteen female LTC staff performed straight-line pushes with two floor-based lifts (conventional, motor driven) loaded with passengers of average and 90th-percentile resident weights over four flooring systems (concrete+vinyl, compliant+vinyl, concrete+carpet, compliant+carpet). Initial and sustained push forces were measured by a handlebar-mounted triaxial load cell and compared to participant-specific tolerance limits. Participants rated pushing difficulty. Novel compliant flooring increased initial and sustained push forces and subjective ratings compared to concrete flooring. Compared to the conventional lift, the motor-driven lift substantially reduced initial and sustained push forces and perceived difficulty of pushing for all four floors and both resident weights. Participants exerted forces above published tolerance limits only when using the conventional lift on the carpet conditions (concrete+carpet, compliant+carpet). With the motor-driven lift only, resident weight did not affect push forces. Novel compliant flooring increased linear push forces generated by LTC staff using floor-based lifts, but forces did not exceed tolerance limits when pushing over compliant+vinyl. The motor-driven lift substantially reduced push forces compared to the conventional lift. Results may help to address risk of work-related musculoskeletal injury, especially in locations with novel compliant flooring. © 2016, Human Factors and Ergonomics Society.

Marital conflict, respiratory sinus arrhythmia, and allostatic load: Interrelations and associations with the development of children’s externalizing behavior

PubMed Central

El-Sheikh, Mona; Hinnant, J. Benjamin

2011-01-01

Allostatic load theory hypothesizes that stress and the body’s responses to stressors contribute to longer term physiological changes in multiple systems over time (allostasis), and that shifts in how these systems function have implications for adjustment and health. We investigated these hypotheses with longitudinal data from two independent samples (n = 413; 219 girls, 194 boys) with repeated measures at ages 8, 9, 10, and 11. Initial parental marital conflict and its change over time indexed children’s exposure to an important familial stressor, which was examined in interaction with children’s respiratory sinus arrhythmia (RSA) reactivity to laboratory tasks (stress response) to predict children’s basal levels of RSA over time. We also investigated children’s sex as an additional possible moderator. Our second research question focused on examining whether initial levels and changes in resting RSA over time predicted children’s externalizing behavior. Boys with a strong RSA suppression response to a frustrating laboratory task who experienced higher initial marital conflict or increasing marital conflict over time showed decreases in their resting RSA over time. In addition, boys’ initial resting RSA (but not changes in resting RSA over time) was negatively related to change over time in externalizing symptoms. Findings for girls were more mixed. Results are discussed in the context of developmental psychobiology, allostatic load, and implications for the development of psychopathology. PMID:21756434

Feedback and Feedforward Control During Walking in Individuals With Chronic Ankle Instability.

PubMed

Yen, Sheng-Che; Corkery, Marie B; Donohoe, Amy; Grogan, Maddison; Wu, Yi-Ning

2016-09-01

Study Design Controlled laboratory study. Background Recurrent ankle sprains associated with chronic ankle instability (CAI) occur not only in challenging sports but also in daily walking. Understanding whether and how CAI alters feedback and feedforward controls during walking may be important for developing interventions for CAI prevention or treatment. Objective To understand whether CAI is associated with changes in feedback and feedforward control when individuals with CAI are subjected to experimental perturbation during walking. Methods Twelve subjects with CAI and 12 control subjects walked on a treadmill while adapting to external loading that generated inversion perturbation at the ankle joint. Ankle kinematics around heel contact during and after the adaptation were compared between the 2 groups. Results Both healthy and CAI groups showed an increase in eversion around heel contact in early adaptation to the external loading. However, the CAI group adapted back toward the baseline, while the healthy controls showed further increase in eversion in late adaptation. When the external loading was removed in the postadaptation period, healthy controls showed an aftereffect consisting of an increase in eversion around heel contact, but the CAI group showed no aftereffect. Conclusion The results provide preliminary evidence that CAI may alter individuals' feedback and feedforward control during walking. J Orthop Sports Phys Ther 2016;46(9):775-783. Epub 5 Aug 2016. doi:10.2519/jospt.2016.6403.

Marital conflict, respiratory sinus arrhythmia, and allostatic load: interrelations and associations with the development of children's externalizing behavior.

PubMed

El-Sheikh, Mona; Hinnant, J Benjamin

2011-08-01

Allostatic load theory hypothesizes that stress and the body's responses to stressors contribute to longer term physiological changes in multiple systems over time (allostasis), and that shifts in how these systems function have implications for adjustment and health. We investigated these hypotheses with longitudinal data from two independent samples (n = 413; 219 girls, 194 boys) with repeated measures at ages 8, 9, 10, and 11. Initial parental marital conflict and its change over time indexed children's exposure to an important familial stressor, which was examined in interaction with children's respiratory sinus arrhythmia (RSA) reactivity to laboratory tasks (stress response) to predict children's basal levels of RSA over time. We also investigated children's sex as an additional possible moderator. Our second research question focused on examining whether initial levels and changes in resting RSA over time predicted children's externalizing behavior. Boys with a strong RSA suppression response to a frustrating laboratory task who experienced higher initial marital conflict or increasing marital conflict over time showed decreases in their resting RSA over time. In addition, boys' initial resting RSA (but not changes in resting RSA over time) was negatively related to change over time in externalizing symptoms. Findings for girls were more mixed. Results are discussed in the context of developmental psychobiology, allostatic load, and implications for the development of psychopathology.

Composite Magnetite and Protein Containing CaCO3 Crystals. External Manipulation and Vaterite → Calcite Recrystallization-Mediated Release Performance.

PubMed

Sergeeva, Alena; Sergeev, Roman; Lengert, Ekaterina; Zakharevich, Andrey; Parakhonskiy, Bogdan; Gorin, Dmitry; Sergeev, Sergey; Volodkin, Dmitry

2015-09-30

Biocompatibility and high loading capacity of mesoporous CaCO3 vaterite crystals give an option to utilize the polycrystals for a wide range of (bio)applications. Formation and transformations of calcium carbonate polymorphs have been studied for decades, aimed at both basic and applied research interests. Here, composite multilayer-coated calcium carbonate polycrystals containing Fe3O4 magnetite nanoparticles and model protein lysozyme are fabricated. The structure of the composite polycrystals and vaterite → calcite recrystallization kinetics are studied. The recrystallization results in release of both loaded protein and Fe3O4 nanoparticles (magnetic manipulation is thus lost). Fe3O4 nanoparticles enhance the recrystallization that can be induced by reduction of the local pH with citric acid and reduction of the polycrystal crystallinity. Oppositely, the layer-by-layer assembled poly(allylamine hydrochloride)/poly(sodium styrenesulfonate) polyelectrolyte coating significantly inhibits the vaterite → calcite recrystallization (from hours to days) most likely due to suppression of the ion exchange giving an option to easily tune the release kinetics for a wide time scale, for example, for prolonged release. Moreover, the recrystallization of the coated crystals results in formulation of multilayer capsules keeping the feature of external manipulation. This study can help to design multifunctional microstructures with tailor-made characteristics for loading and controlled release as well as for external manipulation.

Analysis and Synthesis of Load Forecasting Data for Renewable Integration Studies: Preprint

DOE Office of Scientific and Technical Information (OSTI.GOV)

Steckler, N.; Florita, A.; Zhang, J.

2013-11-01

As renewable energy constitutes greater portions of the generation fleet, the importance of modeling uncertainty as part of integration studies also increases. In pursuit of optimal system operations, it is important to capture not only the definitive behavior of power plants, but also the risks associated with systemwide interactions. This research examines the dependence of load forecast errors on external predictor variables such as temperature, day type, and time of day. The analysis was utilized to create statistically relevant instances of sequential load forecasts with only a time series of historic, measured load available. The creation of such load forecastsmore » relies on Bayesian techniques for informing and updating the model, thus providing a basis for networked and adaptive load forecast models in future operational applications.« less

Ammonia Release on ISS

NASA Technical Reports Server (NTRS)

Macatangay, Ariel

2009-01-01

Crew: Approximately 53% metabolic load Product of protein metabolism Limit production of ammonia by external regulation NOT possbile Payloads Potential source Scientific experiments Thorough safety review ensures sufficient levels of containment

Kinematics of Different Components of the Posterolateral Corner of the Knee in the Lateral Collateral Ligament-intact State: A Human Cadaveric Study.

PubMed

Domnick, Christoph; Frosch, Karl-Heinz; Raschke, Michael J; Vogel, Nils; Schulze, Martin; von Glahn, Mathias; Drenck, Tobias C; Herbort, Mirco

2017-10-01

To determine the static stabilizing effects of different anatomical structures of the posterolateral corner (PLC) of the knee in the lateral collateral ligament (LCL)-intact state. Thirteen fresh-frozen human cadaveric knees were dissected and tested using an industrial robot with an optical tracking system. Kinematics were determined for 134 N anterior/posterior loads, 10 N m valgus/varus loads, and 5 N m internal/external rotatory loads in 0°, 20°, 30°, 60°, and 90° of knee flexion. The PLC structures were dissected and consecutively released: (I) intact knee joint, (II) with released posterior cruciate ligament (PCL), (III) popliteomeniscal fibers, (IV) popliteofibular ligament, (V) arcuat and popliteotibial fibers, (VI) popliteus tendon (PLT), and (VII) LCL. Repeated-measures analysis of variance was performed with significance set at P < .05. After releasing the PCL, posterior tibial translation increased by 5.2 mm at 20° to 9.4 mm at 90° of joint flexion (P < .0001). A mild 1.8° varus instability was measured in 0° of flexion (P = .0017). After releasing the PLC structures, posterior tibial translation further increased by 2.9 mm at 20° to 5.9 mm at 90° of flexion (P < .05) and external rotation angle increased by 2.6° at 0° to 7.9° at 90° of flexion (P < .05, vs II). Varus stability did not decrease. Mild differences between states V and VI were found in 60° and 90° external rotation tests (2.1° and 3.1°; P < .05). The connecting ligaments/fibers to the PLT act as a primary static stabilizer against external rotatory loads and a secondary stabilizer against posterior tibial loads (when PCL is injured). After releasing these structures, most static stabilizing function of the intact PLT is lost. The PLC has no varus-stabilizing function in the LCL-intact knee. Anatomy and function of these structures for primary and secondary joint stability should be considered for clinical diagnostics and when performing surgery in the PLC. Copyright © 2017 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.

Effects of resistance training at different loads on inflammatory markers in young adults.

PubMed

Forti, Louis Nuvagah; Van Roie, Evelien; Njemini, Rose; Coudyzer, Walter; Beyer, Ingo; Delecluse, Christophe; Bautmans, Ivan

2017-03-01

Suppressing inflammaging at an early stage in life via exercise might prevent chronic diseases later in life. The aim was to investigate the influence of resistance training at different external loads on inflammatory markers in healthy young adults. Serum was collected for basal levels of cytokines (IL-1beta, IL-6, IL-8, sTNFR1, IL-1RA, IL-10 and GM-CSF) before and after 9 weeks exercise from 36 young (22 ± 2 years) healthy subjects who were randomized to three times weekly supervised resistance training at either HI max (n = 12, 1 × 10-12 repetitions at 80% 1RM), LO (n = 12, 1 × 10-12 repetitions at 40% 1RM), or LO max (n = 12, 1 × 10-12 repetitions at 40% 1RM preceded by 60 repetitions at 20-25% 1RM) respectively. Overall, IL-8 increased (p < 0.001) and IL-6 decreased (p = 0.001) after training, but no significant time*group interaction was found (respectively, p = 0.283 and p = 0.058 for IL-8 and IL-6). When analyzed separately, IL-8 increased significantly in HI max (p = 0.022) and LO max (p = 0.024); and IL-6 decreased significantly in LO max (p = 0.009) and LO (p = 0.013). No significant overall time effect was observed for sTNFR1 and IL-1RA; however, in HI max sTNFR1 (p = 0.031) and IL-1RA (p = 0.014) increased significantly, but remained unchanged in LO max and LO. IL-1beta, IL-10 and GM-CSF levels remained undetectable in most participants. Nine weeks of resistance training-irrespective of the external load-have beneficial effects on circulating IL-8 and IL-6. In addition, training at high external load increases the anti-inflammatory cytokines sTNFR1 and IL-1RA. The results of this study show that resistance training has anti-inflammatory effects in healthy young persons and that the response of the different inflammatory mediators depends on the magnitude of the external load.

Preparation and physicochemical characteristics of polylactide microspheres of emamectin benzoate by modified solvent evaporation/extraction method.

PubMed

Zhang, Shao Fei; Chen, Peng Hao; Zhang, Fei; Yang, Yan Fang; Liu, De Kun; Wu, Gang

2013-12-18

Emamectin benzoate is highly effective against insect pests and widely used in the world. However, its biological activity is limited because of high resistance of target insects and rapid degradation speed in fields. Preparation and physicochemical characterization of degradable microcapsules of emamectin benzoate were studied by modified solvent evaporation/extraction method using polylactide (PLA) as wall material. The influence of different compositions of the solvent in internal organic phase and external aqueous phase on diameter, span, pesticide loading, and entrapment rate of the microspheres was investigated. The results indicated that the process of solvent extraction and the formation of the microcapsules would be accelerated by adding water-miscible organic solvents such as ethyl ether, acetone, ethyl acetate, or n-butanol into internal organic phase and external aqueous phase. Accelerated formation of the microcapsules would result in entrapment rates of emamectin benzoate increased to as high as 97%. In addition, by adding ethanol into the external aqueous phase, diameters would reduce to 6.28 μm, whereas the loading efficiency of emamectin benzoate did not increase. The PLA microspheres prepared under optimum conditions were smoother and more spherical. The degradation rate in PLA microspheres of emamectin benzoate on the 10th day was 4.29 ± 0.74%, whereas the degradation rates of emamectin benzoate in methanol solution and solid technical material were 46.3 ± 2.11 and 22.7 ± 1.51%, respectively. The PLA skeleton had combined with emamectin benzoate in an amorphous or molecular state by using differential scanning calorimetry (DSC) determination. The results indicated that PLA microspheres of emamectin benzoate with high entrapment rate, loading efficiency, and physicochemical characteristics could be obtained by adding water-miscible organic solvents into the internal organic phase and external aqueous phase.

Effect of forearm axially rotated posture on shoulder load and shoulder abduction / flexion angles in one-armed arrest of forward falls.

PubMed

Hsu, Hsiu-Hao; Chou, You-Li; Lou, Shu-Zon; Huang, Ming-Jer; Chou, Paul Pei-Hsi

2011-03-01

Falling onto the outstretched hand is the most common cause of upper extremity injury. This study develops an experimental model for evaluating the shoulder load during a simulated forward fall onto one hand with three different forearm axially rotated postures, and examines the shoulder abduction angle and shoulder flexion angle in each case. Fifteen healthy young male subjects with an average age of 23.7 years performed a series of one-armed arrests from a height of 5 cm onto a force plate. The kinematics and kinetics of the upper extremity were analyzed for three different forearm postures, namely 45° externally rotated, non-rotated, and 45° internally rotated. The shoulder joint load and shoulder abduction/flexion angles were significantly dependent on the rotational posture of the forearm. The shoulder medio-lateral shear forces in the externally rotated group were found to be 1.61 and 2.94 times higher than those in the non-rotated and internally rotated groups, respectively. The shoulder flexion angles in the externally rotated, non-rotated and internally rotated groups were 0.6°, 8.0° and 19.2°, respectively, while the corresponding shoulder abduction angles were 6.1°, 34.1° and 46.3°, respectively. In falls onto the outstretched hand, an externally rotated forearm posture should be avoided in order to reduce the medio-lateral shear force acting on the shoulder joint. In falls of this type, a 45° internally rotated forearm posture represents the most effective fall strategy in terms of minimizing the risk of upper extremity injuries. Copyright © 2010 Elsevier Ltd. All rights reserved.

Self-regulating control of parasitic loads in a fuel cell power system

NASA Technical Reports Server (NTRS)

Vasquez, Arturo (Inventor)

2011-01-01

A fuel cell power system comprises an internal or self-regulating control of a system or device requiring a parasitic load. The internal or self-regulating control utilizes certain components and an interconnection scheme to produce a desirable, variable voltage potential (i.e., power) to a system or device requiring parasitic load in response to varying operating conditions or requirements of an external load that is connected to a primary fuel cell stack of the system. Other embodiments comprise a method of designing such a self-regulated control scheme and a method of operating such a fuel cell power system.

Failure criterion for materials with spatially correlated mechanical properties

NASA Astrophysics Data System (ADS)

Faillettaz, J.; Or, D.

2015-03-01

The role of spatially correlated mechanical elements in the failure behavior of heterogeneous materials represented by fiber bundle models (FBMs) was evaluated systematically for different load redistribution rules. Increasing the range of spatial correlation for FBMs with local load sharing is marked by a transition from ductilelike failure characteristics into brittlelike failure. The study identified a global failure criterion based on macroscopic properties (external load and cumulative damage) that is independent of spatial correlation or load redistribution rules. This general metric could be applied to assess the mechanical stability of complex and heterogeneous systems and thus provide an important component for early warning of a class of geophysical ruptures.

Four dimensional X-ray imaging of deformation modes in organic-rich Green River Shale retorted under uniaxial compression

NASA Astrophysics Data System (ADS)

Kobchenko, M.; Pluymakers, A.; Cordonnier, B.; Tairova, A.; Renard, F.

2017-12-01

Time-lapse imaging of fracture network development in organic-rich shales at elevated temperatures while kerogen is retorted allows characterizing the development of microfractures and the onset of primary migration. When the solid organic matter is transformed to hydrocarbons with lower molecular weight, the local pore-pressure increases and drives the propagation of hydro-fractures sub-parallel to the shale lamination. On the scale of samples of several mm size, these fractures can be described as mode I opening, where fracture walls dilate in the direction of minimal compression. However, so far experiments coupled to microtomography in situ imaging have been performed on samples where no load was imposed. Here, an external load was applied perpendicular to the sample laminations and we show that this stress state slows down, but does not stop, the propagation of fracture along bedding. Conversely, microfractures also propagate sub-perpendicular to the shale lamination, creating a percolating network in three dimensions. To monitor this process we have used a uniaxial compaction rig combined with in-situ heating from 50 to 500 deg C, while capturing three-dimensional X-ray microtomography scans at a voxel resolution of 2.2 μm; Data were acquired at beamline ID19 at the European Synchrotron Radiation Facility. In total ten time-resolved experiments were performed at different vertical loading conditions, with and without lateral passive confinement and different heating rates. At high external load the sample fails by symmetric bulging, while at lower external load the reaction-induced fracture network develops with the presence of microfractures both sub-parallel and sub-perpendicular to the bedding direction. In addition, the variation of experimental conditions allows the decoupling of the effects of the hydrocarbon decomposition reaction on the deformation process from the influence of thermal stress heating on the weakening and failure mode of immature shale.

Absence of equifinality of hand position in a double-step unloading task.

PubMed

Norouzi-Gheidari, Nahid; Archambault, Philippe

2010-08-01

Equifinality, during arm reaching movements, relates to the capacity of the neuromuscular system to attain the same final position in the presence or absence of transient perturbations. There have been several controversies regarding equifinality in the literature. A brief elastic perturbation, applied during a fast arm movement or just before its initiation, typically does not affect final arm position. On the other hand, several experiments have shown that velocity-dependent perturbations, such as Coriolis force or negative damping, while transient in nature, have a significant effect on final arm position when compared to unperturbed movements. In this study, an unloading paradigm was used to study the role of reflexes with respect to equifinality. The effects on final arm position of suddenly decreasing a static load maintained by fourteen subjects were analyzed. Subjects maintained an initial load produced by a double-joint manipulandum moving in the horizontal plane. The load was suddenly decreased, either in one or in two successive steps with different time intervals, resulting in a rapid reflex-mediated change in arm position. Unloading led to short-latency changes in the activity of shoulder and elbow muscles and significant variations in tonic activity. It was found that the final hand position was shorter for double- versus single-step unloading if the time between two successive changes in load was greater than 100 ms. With a shorter time interval, the final hand positions were the same. This difference in final hand positions was inversely proportional to the hand velocity at the time of the second change in load. Further, agonist/antagonist co-activation increased in double-step unloading. Thus, the change in both the load and the movement velocity may influence the magnitude of the unloading reflex. This may be indicative of a dependence of stretch reflexes on velocity. Perturbation may cause a reflex-mediated increase in joint stiffness, which could explain why equifinality is not preserved after some perturbations, such as velocity-dependant external forces.

Dyadic flexibility and positive affect in parent–child coregulation and the development of child behavior problems

PubMed Central

LUNKENHEIMER, ERIKA S.; OLSON, SHERYL L.; HOLLENSTEIN, TOM; SAMEROFF, ARNOLD J.; WINTER, CHARLOTTE

2018-01-01

Parent–child dyadic rigidity and negative affect contribute to children’s higher levels of externalizing problems. The present longitudinal study examined whether the opposite constructs of dyadic flexibility and positive affect predicted lower levels of externalizing behavior problems across the early childhood period. Mother–child (N = 163) and father–child (n = 94) dyads engaged in a challenging block design task at home when children were 3 years old. Dynamic systems methods were used to derive dyadic positive affect and three indicators of dyadic flexibility (range, dispersion, and transitions) from observational coding. We hypothesized that the interaction between dyadic flexibility and positive affect would predict lower levels of externalizing problems at age 5.5 years as rated by mothers and teachers, controlling for stability in externalizing problems, task time, child gender, and the child’s effortful control. The hypothesis was supported in predicting teacher ratings of child externalizing from both mother–child and father–child interactions. There were also differential main effects for mothers and fathers: mother–child flexibility was detrimental and father–child flexibility was beneficial for child outcomes. Results support the inclusion of adaptive and dynamic parent–child coregulation processes in the study of children’s early disruptive behavior. PMID:23786697

Spatial working memory load affects counting but not subitizing in enumeration.

PubMed

Shimomura, Tomonari; Kumada, Takatsune

2011-08-01

The present study investigated whether subitizing reflects capacity limitations associated with two types of working memory tasks. Under a dual-task situation, participants performed an enumeration task in conjunction with either a spatial (Experiment 1) or a nonspatial visual (Experiment 2) working memory task. Experiment 1 showed that spatial working memory load affected the slope of a counting function but did not affect subitizing performance or subitizing range. Experiment 2 showed that nonspatial visual working memory load affected neither enumeration efficiency nor subitizing range. Furthermore, in both spatial and nonspatial memory tasks, neither subitizing efficiency nor subitizing range was affected by amount of imposed memory load. In all the experiments, working memory load failed to influence slope, subitizing range, or overall reaction time. These findings suggest that subitizing is performed without either spatial or nonspatial working memory. A possible mechanism of subitizing with independent capacity of working memory is discussed.

Longitudinal Weld Land Buckling in Compression-Loaded Orthogrid Cylinders

NASA Technical Reports Server (NTRS)

Thornburgh, Robert P.; Hilburger, Mark W.

2010-01-01

Large stiffened cylinders used in launch vehicles (LV), such as the Space Shuttle External Tank, are manufactured by welding multiple curved panel sections into complete cylinders. The effects of the axial weld lands between the panel sections on the buckling load were studied, along with the interaction between the acreage stiffener arrangement and the weld land geometry. This document contains the results of the studies.

49 CFR Appendix D to Part 238 - Requirements for External Fuel Tanks on Tier I Locomotives

Code of Federal Regulations, 2013 CFR

2013-10-01

... vertical acceleration of 2g, without exceeding the ultimate strength of the material. The load is assumed... maximize the vertical clearance between the top of the rail and the bottom of the fuel tank. (2) Load case... equivalent to one half the weight of the locomotive at a vertical acceleration of 2g, without exceeding the...

49 CFR Appendix D to Part 238 - Requirements for External Fuel Tanks on Tier I Locomotives

Code of Federal Regulations, 2010 CFR

2010-10-01

... vertical acceleration of 2g, without exceeding the ultimate strength of the material. The load is assumed... maximize the vertical clearance between the top of the rail and the bottom of the fuel tank. (2) Load case... equivalent to one half the weight of the locomotive at a vertical acceleration of 2g, without exceeding the...

49 CFR Appendix D to Part 238 - Requirements for External Fuel Tanks on Tier I Locomotives

Code of Federal Regulations, 2014 CFR

2014-10-01

... vertical acceleration of 2g, without exceeding the ultimate strength of the material. The load is assumed... maximize the vertical clearance between the top of the rail and the bottom of the fuel tank. (2) Load case... equivalent to one half the weight of the locomotive at a vertical acceleration of 2g, without exceeding the...

Externally Pressurized Journal Gas Bearings

NASA Technical Reports Server (NTRS)

Laub, John H.

1959-01-01

Externally pressurized gas-lubricated bearings with multiple orifice feed are investigated. An analytical treatment is developed for a semi-cylindrical bearing with 9 orifices and for a cylindrical journal bearing with 192 radial and 24 axial orifices. Experiments are described on models of the two bearing configurations with specially designed fixtures which incorporate pneumatic loading and means for determining pressure profiles, gas flow and gap height. The correlation between theory and experiment is satisfactory.

Positive and Negative Affect and Adolescent Adjustment: Moderation Effects of Prefrontal Functioning.

PubMed

Brieant, Alexis; Holmes, Christopher J; Maciejewski, Dominique; Lee, Jacob; Deater-Deckard, Kirby; King-Casas, Brooks; Kim-Spoon, Jungmeen

2018-03-01

We examined whether cognitive control moderates the effects of emotion on adolescent internalizing and externalizing symptomatology in a longitudinal study of 138 adolescents. Self-reported positive affect (PA) and negative affect and behavioral and neural indicators of cognitive control, indexed by performance and prefrontal hemodynamic response during a cognitive interference task, were collected at Time 1. Self-reported internalizing and externalizing symptomatology were collected at Time 1 and Time 2 (1 year later). Results indicated that higher PA predicted decreases in externalizing symptomatology, but only for adolescents with poor neural cognitive control. No moderation effects were found for behavioral cognitive control. Findings imply the beneficial effects of PA on the development of externalizing problems among adolescents with poor prefrontal functioning. © 2018 Society for Research on Adolescence.

A method for continuous monitoring of the Ground Reaction Force during daily activity

NASA Technical Reports Server (NTRS)

Whalen, Robert; Quintana, Jason; Emery, Jeff

1993-01-01

Theoretical models and experimental studies of bone remodeling have identified peak cyclic force levels (or cyclic tissue strain energy density), number of daily loading cycles, and load (strain) rate as possible contributors to bone modeling and remodeling stimulus. To test our theoretical model and further investigate the influence of mechanical forces on bone density, we have focused on the calcaneus as a model site loaded by calcaneal surface tractions which are predominantly determined by the magnitude of the external ground reaction force (GRF).

14 CFR 137.29 - General.

Code of Federal Regulations, 2010 CFR

2010-01-01

... this chapter and involving only the dispensing of water on forest fires by rotorcraft external-load... agriculture, horticulture, or forest preservation in accordance with the operating rules of this subpart. (d...

14 CFR 137.29 - General.

Code of Federal Regulations, 2011 CFR

2011-01-01

... this chapter and involving only the dispensing of water on forest fires by rotorcraft external-load... agriculture, horticulture, or forest preservation in accordance with the operating rules of this subpart. (d...

Magnetoresistors as a tool for investigating the mechanical properties of ferromagnetic materials

NASA Astrophysics Data System (ADS)

Kaleta, Jerzy; Tumański, Slawomir; Żebracki, Jacek

1996-07-01

We have investigated the possibility of applying the Villari effect for measurements of the dependence of deformation on the external loading. The magnetic field arising due to the deformation has been measured with a Permalloy magnetoresistive sensor. The plot of the dependence of the external field H on the strain ɛ agrees almost perfectly with the classical dependence σ = f( ɛ) in tensile tests. In steel and nickel samples stress changes in the range 0-500 MPa were accompanied by changes in the external magnetic field in the range 0-300 A/m.

Internal loading of phosphorus in western Lake Erie

USGS Publications Warehouse

Matisoff, Gerald; Kaltenberg, Eliza M.; Steely, Rebecca L.; Hummel, Stephanie K.; Seo, Jinyu; Gibbons, Kenneth J.; Bridgeman, Thomas B.; Seo, Youngwoo; Behbahani, Mohsen; James, William F.; Johnson, Laura; Doan, Phuong; Dittrich, Maria; Evans, Mary Anne; Chaffin, Justin D.

2016-01-01

This study applied eight techniques to obtain estimates of the diffusive flux of phosphorus (P) from bottom sediments throughout the western basin of Lake Erie. The flux was quantified from both aerobic and anaerobic incubations of whole cores; by monitoring the water encapsulated in bottom chambers; from pore water concentration profiles measured with a phosphate microelectrode, a diffusive equilibrium in thin films (DET) hydrogel, and expressed pore waters; and from mass balance and biogeochemical diagenetic models. Fluxes under aerobic conditions at summertime temperatures averaged 1.35 mg P/m2/day and displayed spatial variability on scales as small as a centimeter. Using two different temperature correction factors, the flux was adjusted to mean annual temperature yielding average annual fluxes of 0.43–0.91 mg P/m2/day and a western basin-wide total of 378–808 Mg P/year as the diffusive flux from sediments. This is 3–7% of the 11,000 Mg P/year International Joint Commission (IJC) target load for phosphorus delivery to Lake Erie from external sources. Using these average aerobic fluxes, the sediment contributes 3.0–6.3 μg P/L as a background internal contribution that represents 20–42% of the IJC Target Concentration of 15 μg P/L for the western basin. The implication is that this internal diffusive recycling of P is unlikely to trigger cyanobacterial blooms by itself but is sufficiently large to cause blooms when combined with external loads. This background flux may be also responsible for delayed response of the lake to any decrease in the external loading.

Comparison of athlete-coach perceptions of internal and external load markers for elite junior tennis training.

PubMed

Murphy, Alistair P; Duffield, Rob; Kellett, Aaron; Reid, Machar

2014-09-01

To investigate the discrepancy between coach and athlete perceptions of internal load and notational analysis of external load in elite junior tennis. Fourteen elite junior tennis players and 6 international coaches were recruited. Ratings of perceived exertion (RPEs) were recorded for individual drills and whole sessions, along with a rating of mental exertion, coach rating of intended session exertion, and athlete heart rate (HR). Furthermore, total stroke count and unforced-error count were notated using video coding after each session, alongside coach and athlete estimations of shots and errors made. Finally, regression analyses explained the variance in the criterion variables of athlete and coach RPE. Repeated-measures analyses of variance and interclass correlation coefficients revealed that coaches significantly (P < .01) underestimated athlete session RPE, with only moderate correlation (r = .59) demonstrated between coach and athlete. However, athlete drill RPE (P = .14; r = .71) and mental exertion (P = .44; r = .68) were comparable and substantially correlated. No significant differences in estimated stroke count were evident between athlete and coach (P = .21), athlete notational analysis (P = .06), or coach notational analysis (P = .49). Coaches estimated significantly greater unforced errors than either athletes or notational analysis (P < .01). Regression analyses found that 54.5% of variance in coach RPE was explained by intended session exertion and coach drill RPE, while drill RPE and peak HR explained 45.3% of the variance in athlete session RPE. Coaches misinterpreted session RPE but not drill RPE, while inaccurately monitoring error counts. Improved understanding of external- and internal-load monitoring may help coach-athlete relationships in individual sports like tennis avoid maladaptive training.

Effects of Bout Duration on Players' Internal and External Loads During Small-Sided Games in Young Soccer Players.

PubMed

Köklü, Yusuf; Alemdaroğlu, Utku; Cihan, Hamit; Wong, Del P

2017-11-01

To investigate the effects of different bout durations on internal and external loads of young soccer players during different small-sided games (SSGs). Fifteen young male soccer players (average age 17 ± 1 y) participated in 2 vs 2, 3 vs 3, and 4 vs 4 SSGs. All games lasted 12 min playing time in total, but each SSG format further consisted of 4 bout durations: continuous (CON: 1 bout × 12 min) or interval with short (SBD: 6 bouts  × 2 min), medium (MBD: 3 bouts × 4 min), or long (LBD: 2 bouts × 6 min) bout durations. During the SSGs, heart-rate (HR) responses and distance covered in different speed zones (walking and low-intensity, moderate-intensity, and high-intensity running) were measured. Rating of perceived exertion (RPE) and blood lactate (La - ) were determined at the end of each SSG. The SBD format elicited significantly lower %HR max responses compared to LBD and CON in all formats (P < .05). The SBD format also showed significantly shorter distances covered in walking and greater distances covered in moderate-intensity running, as well as significantly greater total distance covered compared to LBD and CON in all formats (P < .05). In addition, LBD produced significantly lower La - and RPE responses than SBD and CON in all formats (P < .05). These results suggest that coaches and sport scientists who want to achieve higher internal loads could use SBD and CON timing protocols, while those who want to achieve higher external loads might prefer to use SBD and MBD when planning all SSG formats.

Characterization of interfragmentary motion associated with common osteosynthesis devices for rat fracture healing studies.

PubMed

Meyers, Nicholaus; Sukopp, Matthias; Jäger, Rudolf; Steiner, Malte; Matthys, Romano; Lapatki, Bernd; Ignatius, Anita; Claes, Lutz

2017-01-01

Rat models are widely used in preclinical studies investigating fracture healing. The interfragmentary movement at a fracture site is critical to the course of healing and therefore demands definition in order to aptly interpret the experimental results. Estimation of this movement requires knowledge of the fixation stiffness and loading. The characteristic loading for the rat femur has been estimated, but the stiffness of fixation used in rat studies has yet to be fully described. This study aimed to determine the 6 degree of freedom stiffness of four commonly used implants, two external fixators (RatExFix and UlmExFix), a locking plate, and a locking intramedullary nail, in all degrees of freedom and estimate the interfragmentary movement under specific physiological loads. The external fixator systems allow the greatest movement. Mounted 45° anterolateral on the femur, the RatExFix allows an average of 0.88 mm of motion in each anatomic direction while the stiffer UlmExFix allows about 0.6 mm of motion. The nail is far stiffer than the other implants investigated while the plate allows movement of an intermediate magnitude. Both the nail and plate demonstrate higher axial than shear stiffness. The relatively large standard deviations in external fixator shear motion imply strong dependence on bone axis alignment across the gap and the precise orientation of the specimen relative to the loading. The smaller standard deviation associated with the nail and plate results from improved alignment and minimization of the influence of rotational positioning of the specimen due to the reduced implant eccentricity relative to the specimen axis. These results show that the interfragmentary movement is complex and varies significantly between fixation devices but establishes a baseline for the evaluation of the results of different studies.

Characterization of interfragmentary motion associated with common osteosynthesis devices for rat fracture healing studies

PubMed Central

Steiner, Malte; Matthys, Romano; Lapatki, Bernd; Ignatius, Anita; Claes, Lutz

2017-01-01

Rat models are widely used in preclinical studies investigating fracture healing. The interfragmentary movement at a fracture site is critical to the course of healing and therefore demands definition in order to aptly interpret the experimental results. Estimation of this movement requires knowledge of the fixation stiffness and loading. The characteristic loading for the rat femur has been estimated, but the stiffness of fixation used in rat studies has yet to be fully described. This study aimed to determine the 6 degree of freedom stiffness of four commonly used implants, two external fixators (RatExFix and UlmExFix), a locking plate, and a locking intramedullary nail, in all degrees of freedom and estimate the interfragmentary movement under specific physiological loads. The external fixator systems allow the greatest movement. Mounted 45° anterolateral on the femur, the RatExFix allows an average of 0.88 mm of motion in each anatomic direction while the stiffer UlmExFix allows about 0.6 mm of motion. The nail is far stiffer than the other implants investigated while the plate allows movement of an intermediate magnitude. Both the nail and plate demonstrate higher axial than shear stiffness. The relatively large standard deviations in external fixator shear motion imply strong dependence on bone axis alignment across the gap and the precise orientation of the specimen relative to the loading. The smaller standard deviation associated with the nail and plate results from improved alignment and minimization of the influence of rotational positioning of the specimen due to the reduced implant eccentricity relative to the specimen axis. These results show that the interfragmentary movement is complex and varies significantly between fixation devices but establishes a baseline for the evaluation of the results of different studies. PMID:28453556

Interactive effects of the affect quality and directional focus of mental imagery on pain analgesia.

PubMed

Alden, A L; Dale, J A; DeGood, D E

2001-06-01

College students (25 men and 25 women) were randomly assigned (within sex) to each of the 4 factorial groups, based on manipulation of affect quality (positive vs. negative) and directional focus (internal vs. external) of mental imagery, and to a control group receiving no manipulation. Both imagery variables had a significant impact on pain tolerance and ratings during a cold-pressor test with positive affect and external imagery producing greater analgesia than their counterpart conditions. Positive affect imagery combined with external imagery resulted in the lowest reported pain amongst the groups. However, self-reported mood descriptors did not consistently parallel the pain tolerance and rating data. Likewise, although heart rate and skin potential responses increased during the cold pressor for the group as a whole, the only significant difference amongst the experimental groups was the relatively higher skin potential reactivity of the positive affect-external imagery group--possibly reflecting greater task engagement for this group. Seemingly, imagery in this situation operates primarily via cognitive, rather than via physiological mediators of the pain experience.

Fundamental considerations in ski binding analysis.

PubMed

Mote, C D; Hull, M L

1976-01-01

1. The static adjustment of a ski binding by hand or by available machines is only an adjustment and is neither a static nor a dynamic evaluation of the binding design. Bindings of different design with identical static adjustments will perform differently in environments in which the forces are static or dynamic. 2. The concept of binding release force is a useful measure of binding adjustment, but it is inappropriate as a criterion for binding evaluation. First, it does not direct attention toward the injury causing mechanism, strain, or displacement in the leg. Second, it is only part of the evaluation in dynamic problems. 3. The binding release decision in present bindings is displacement controlled. The relative displacement of the boot and ski is the system variable. For any specified relative displacement the binding force can be any of an infinite number of possibilities determined by the loading path. 4. The response of the leg-ski system to external impulses applied to the ski is independent of the boot-ski relative motion as long as the boot recenters quickly in the binding. Response is dependent upon the external impulse plus system inertia, damping and stiffness. 5. When tested under half sinusoidal forces applied to a test ski, all bindings will demonstrate static and impulse loading regions. In the static region the force drives the binding to a relative release displacement. In the impulse region the initial velocity of the ski drives the binding to a release displacement. 6. The transition between the static and impulse loading regions is determined by the binding's capacity to store and dissipate energy along the principal loading path. Increased energy capacity necessitates larger external impulses to produce release. 7. In all bindings examined to date, the transmitted leg displacement or strain at release under static loading exceeds leg strain under dynamic or impact loading. Because static loading is responsible for many injuries, a skier should be able to release his bindings in every mode by simply pulling or twisting his foot outward. If that cannot be done without injury, the skier has identified for himself one type of fall that will result in injury. 8. And lastly, a little advice from Ben Franklin--"Carelessness does more harm than a want of knowledge."

Using Simulation Technique to overcome the multi-collinearity problem for estimating fuzzy linear regression parameters.

NASA Astrophysics Data System (ADS)

Mansoor Gorgees, Hazim; Hilal, Mariam Mohammed

2018-05-01

Fatigue cracking is one of the common types of pavement distresses and is an indicator of structural failure; cracks allow moisture infiltration, roughness, may further deteriorate to a pothole. Some causes of pavement deterioration are: traffic loading; environment influences; drainage deficiencies; materials quality problems; construction deficiencies and external contributors. Many researchers have made models that contain many variables like asphalt content, asphalt viscosity, fatigue life, stiffness of asphalt mixture, temperature and other parameters that affect the fatigue life. For this situation, a fuzzy linear regression model was employed and analyzed by using the traditional methods and our proposed method in order to overcome the multi-collinearity problem. The total spread error was used as a criterion to compare the performance of the studied methods. Simulation program was used to obtain the required results.

[The treatment of extremity bone fractures in the cases of combined injuries].

PubMed

Peshekhonov, E V; Galin, V I; Zudilin, A V; Zubok, D N

2006-12-01

The experience of treatment of 76 injured with fractures of two or more extremities in combination with affection of other anatomical areas (head, abdomen, breast, pelvis) was summarized. The extrafocal osteosynthesis was preferable because this method is characterized by low traumatism, minimal blood loss, adequate reposition, stable immobilization and possibility of early load in the apparatus of external fixation. Immersed osteosynthesis is used with great caution as it can cause the development of fat embolism. One-stage operations were performed in 26.3% victims. Their treatment periods were significantly shorter than during the multi-stage operations. One-stage operations for polytrauma have the following advantages over the multi-stage operations: single narcosis, simplified treatment in reanimation department, one post-operation period, quick rehabilitation and economic benefit. The extrafocal osteosynthesis causes less purulent complications.

Engineering three-dimensional cell mechanical microenvironment with hydrogels.

PubMed

Huang, Guoyou; Wang, Lin; Wang, Shuqi; Han, Yulong; Wu, Jinhui; Zhang, Qiancheng; Xu, Feng; Lu, Tian Jian

2012-12-01

Cell mechanical microenvironment (CMM) significantly affects cell behaviors such as spreading, migration, proliferation and differentiation. However, most studies on cell response to mechanical stimulation are based on two-dimensional (2D) planar substrates, which cannot mimic native three-dimensional (3D) CMM. Accumulating evidence has shown that there is a significant difference in cell behavior in 2D and 3D microenvironments. Among the materials used for engineering 3D CMM, hydrogels have gained increasing attention due to their tunable properties (e.g. chemical and mechanical properties). In this paper, we provide an overview of recent advances in engineering hydrogel-based 3D CMM. Effects of mechanical cues (e.g. hydrogel stiffness and externally induced stress/strain in hydrogels) on cell behaviors are described. A variety of approaches to load mechanical stimuli in 3D hydrogel-based constructs are also discussed.

Estimation of the Unsteady Aerodynamic Load on Space Shuttle External Tank Protuberances from a Component Wind Tunnel Test

NASA Technical Reports Server (NTRS)

Panda, Jayatana; Martin, Fred W.; Sutliff, Daniel L.

2008-01-01

At the wake of the Columbia (STS-107) accident it was decided to remove the Protuberance Aerodynamic Load (PAL) Ramp that was originally intended to protect various protuberances outside of the Space Shuttle External Tank from high buffet load induced by cross-flows at transonic speed. In order to establish the buffet load without the PAL ramp, a wind tunnel test was conducted where segments of the protuberances were instrumented with dynamic pressure transducers; and power-spectra of sectional lift and drag forces at various span-wise locations between two adjacent support brackets were measured under different cross flow angles, Mach number and other conditions. Additionally, frequency-dependent spatial correlations between the sectional forces were also established. The sectional forces were then adjusted by the correlation length to establish span-averaged spectra of normal and lateral forces that can be suitably "added" to various other unsteady forces encountered by the protuberance. This paper describes the methodology used for calculating the correlation-adjusted power spectrum of the buffet load. A second part of the paper describes wind-tunnel results on the difference in the buffet load on the protuberances with and without the PAL ramp. In general when the ramp height is the same as that of the protuberance height, such as that found on the liquid Oxygen part of the tank, the ramp is found to cause significant reduction of the unsteady aerodynamic load. However, on the liquid Hydrogen part of the tank, where the Oxygen feed-line is far larger in diameter than the height of the PAL ramp, little protection is found to be available to all but the Cable Tray.

Knee Joint Kinetics in Relation to Commonly Prescribed Squat Loads and Depths

PubMed Central

Cotter, Joshua A.; Chaudhari, Ait M.; Jamison, Steve T.; Devor, Steven T.

2014-01-01

Controversy exists regarding the safety and performance benefits of performing the squat exercise to depths beyond 90° of knee flexion. Our aim was to compare the net peak external knee flexion moments (pEKFM) experienced over typical ranges of squat loads and depths. Sixteen recreationally trained males (n = 16; 22.7 ± 1.1 yrs; 85.4 ± 2.1 kg; 177.6 ± 0.96 cm; mean ± SEM) with no previous lower limb surgeries or other orthopedic issues and at least one year of consistent resistance training experience while utilizing the squat exercise performed single repetition squat trials in a random order at squat depths of above parallel, parallel, and below parallel. Less than one week before testing, one repetition maximum (1RM) values were found for each squat depth. Subsequent testing required subjects to perform squats at the three depths with three different loads: unloaded, 50% 1RM, and 85% 1RM (nine total trials). Force platform and kinematic data were collected to calculate pEKFM. To assess differences among loads and depths, a two-factor (load and depth) repeated-measures ANOVA with significance set at the P < 0.05 level was used. Squat 1RM significantly decreased 13.6% from the above parallel to parallel squat and another 3.6% from the parallel to the below parallel squat (P < 0.05). Net peak external knee flexion moments significantly increased as both squat depth and load were increased (P ≤ 0.02). Slopes of pEKFM were greater from unloaded to 50% 1RM than when progressing from 50% to 85% 1RM (P < 0.001). The results suggest that that typical decreases in squat loads used with increasing depths are not enough to offset increases in pEKFM. PMID:23085977

Measurement of inspiratory muscle performance with incremental threshold loading: a comparison of two techniques.

PubMed Central

Bardsley, P A; Bentley, S; Hall, H S; Singh, S J; Evans, D H; Morgan, M D

1993-01-01

BACKGROUND--Incremental threshold loading (ITL) is a test of inspiratory muscle performance which is usually performed by breathing through a weighted inspiratory plunger, the load on the inspiratory muscles being increased by externally adding weights to the intake valve. This is not a true threshold device and may be inaccurate. This method was compared with a true threshold device consisting of a solenoid valve which only opens to supply air at a predetermined negative mouth pressure. METHODS--Six naive, normal subjects (three men and three women) aged 22-24 years underwent three tests using each system. The inspiratory loads were increased every minute by equivalent amounts, -10 cm H2O with the solenoid valve and by 50 g with the weighted plunger, until the subjects could not inspire or sustain inspiration for a full minute. Six experienced subjects (four men and two women) aged 23-41 years were subsequently randomised to perform ITL with the solenoid valve, twice with the breathing pattern fixed and twice free. RESULTS--The solenoid valve generated a more accurate mouth pressure response and was less variable at higher loads than the weighted plunger. The work performed (expressed as the pressure-time product) was less with the solenoid valve but was more reproducible. ITL with the solenoid valve was not influenced by controlling the breathing pattern of the subjects. CONCLUSIONS--The solenoid valve has several features that make it superior to the weighted plunger as a device for ITL. It generates a more accurate mouth pressure response which is less variable at higher loads. Increases in load are smoother and quicker to introduce. ITL with the solenoid valve is not influenced by varying breathing patterns and does not require any external regulation. PMID:8511732

Measurement of inspiratory muscle performance with incremental threshold loading: a comparison of two techniques.

PubMed

Bardsley, P A; Bentley, S; Hall, H S; Singh, S J; Evans, D H; Morgan, M D

1993-04-01

Incremental threshold loading (ITL) is a test of inspiratory muscle performance which is usually performed by breathing through a weighted inspiratory plunger, the load on the inspiratory muscles being increased by externally adding weights to the intake valve. This is not a true threshold device and may be inaccurate. This method was compared with a true threshold device consisting of a solenoid valve which only opens to supply air at a predetermined negative mouth pressure. Six naive, normal subjects (three men and three women) aged 22-24 years underwent three tests using each system. The inspiratory loads were increased every minute by equivalent amounts, -10 cm H2O with the solenoid valve and by 50 g with the weighted plunger, until the subjects could not inspire or sustain inspiration for a full minute. Six experienced subjects (four men and two women) aged 23-41 years were subsequently randomised to perform ITL with the solenoid valve, twice with the breathing pattern fixed and twice free. The solenoid valve generated a more accurate mouth pressure response and was less variable at higher loads than the weighted plunger. The work performed (expressed as the pressure-time product) was less with the solenoid valve but was more reproducible. ITL with the solenoid valve was not influenced by controlling the breathing pattern of the subjects. The solenoid valve has several features that make it superior to the weighted plunger as a device for ITL. It generates a more accurate mouth pressure response which is less variable at higher loads. Increases in load are smoother and quicker to introduce. ITL with the solenoid valve is not influenced by varying breathing patterns and does not require any external regulation.

Frequency effects on the stability of a journal bearing for periodic loading

NASA Technical Reports Server (NTRS)

Vijayaraghavan, D.; Brewe, D. E.

1991-01-01

The stability of a journal bearing is numerically predicted when a unidirectional periodic external load is applied. The analysis is performed using a cavitation algorithm, which mimics the Jakobsson-Floberg and Olsson (JFO) theory by accounting for the mass balance through the complete bearing. Hence, the history of the film is taken into consideration. The loading pattern is taken to be sinusoidal and the frequency of the load cycle is varied. The results are compared with the predictions using Reynolds boundary conditions for both film rupture and reformation. With such comparisons, the need for accurately predicting the cavitation regions for complex loading patterns is clearly demonstrated. For a particular frequency of loading, the effects of mass, amplitude of load variation and frequency of journal speed are also investigated. The journal trajectories, transient variations in fluid film forces, net surface velocity and minimum film thickness, and pressure profiles are also presented.

Self-organized dynamics in local load-sharing fiber bundle models.

PubMed

Biswas, Soumyajyoti; Chakrabarti, Bikas K

2013-10-01

We study the dynamics of a local load-sharing fiber bundle model in two dimensions under an external load (which increases with time at a fixed slow rate) applied at a single point. Due to the local load-sharing nature, the redistributed load remains localized along the boundary of the broken patch. The system then goes to a self-organized state with a stationary average value of load per fiber along the (increasing) boundary of the broken patch (damaged region) and a scale-free distribution of avalanche sizes and other related quantities are observed. In particular, when the load redistribution is only among nearest surviving fiber(s), the numerical estimates of the exponent values are comparable with those of the Manna model. When the load redistribution is uniform along the patch boundary, the model shows a simple mean-field limit of this self-organizing critical behavior, for which we give analytical estimates of the saturation load per fiber values and avalanche size distribution exponent. These are in good agreement with numerical simulation results.

Vande Hei exercises on COLBERT/T2 Treadmill

NASA Image and Video Library

2017-09-23

iss053e040103 (ept. 23, 2017) --- Astronaut Mark Vande Hei, Expedition 53 Flight Engineer, exercises on the COLBERT (Combined Operational Load Bearing External Resistance Treadmill) in the Tranquility module.

Predicting the conditions under which vibroacoustic resonances with external periodic loads occur in the primary coolant circuits of VVER-based NPPs

NASA Astrophysics Data System (ADS)

Proskuryakov, K. N.; Fedorov, A. I.; Zaporozhets, M. V.

2015-08-01

The accident at the Japanese Fukushima Daiichi nuclear power plant (NPP) caused by an earthquake showed the need of taking further efforts aimed at improving the design and engineering solutions for ensuring seismic resistance of NPPs with due regard to mutual influence of the dynamic processes occurring in the NPP building structures and process systems. Resonance interaction between the vibrations of NPP equipment and coolant pressure pulsations leads to an abnormal growth of dynamic stresses in structural materials, accelerated exhaustion of equipment service life, and increased number of sudden equipment failures. The article presents the results from a combined calculation-theoretical and experimental substantiation of mutual amplification of two kinds of external periodic loads caused by rotation of the reactor coolant pump (RCP) rotor and an earthquake. The data of vibration measurements at an NPP are presented, which confirm the predicted multiple amplification of vibrations in the steam generator and RCP at a certain combination of coolant thermal-hydraulic parameters. It is shown that the vibration frequencies of the main equipment may fall in the frequency band corresponding to the maximal values in the envelope response spectra constructed on the basis of floor accelerograms. The article presents the results from prediction of conditions under which vibroacoustic resonances with external periodic loads take place, which confirm the occurrence of additional earthquake-induced multiple growth of pressure pulsation intensity in the steam generator at the 8.3 Hz frequency and additional multiple growth of vibrations of the RCP and the steam generator cold header at the 16.6 Hz frequency. It is shown that at the elastic wave frequency equal to 8.3 Hz in the coolant, resonance occurs with the frequency of forced vibrations caused by the rotation of the RCP rotor. A conclusion is drawn about the possibility of exceeding the design level of equipment vibrations under the effect of external periodic loads caused by an earthquake when the vibration frequency of the reactor plant main equipment and the frequency of elastic waves fall in the frequency band corresponding to the maximal values of envelope response spectra.

Dynamic considerations for composite metal-rubber laminate acoustic power coupling bellows with application to thermoacoustic refrigeration

NASA Astrophysics Data System (ADS)

Smith, Robert William

Many electrically driven thermoacoustic refrigerators have employed corrugated metal bellows to couple work from an electro-mechanical transducer to the working fluid typically. An alternative bellows structure to mediate this power transfer is proposed: a laminated hollow cylinder comprised of alternating layers of rubber and metal 'hoop-stack'. Fatigue and visoelastic power dissipation in the rubber are critical considerations; strain energy density plays a role in both. Optimal aspect ratios for a rectangle corss-section in the rubber, for given values of bellows axial strain and oscillatory pressure loads are discussed. Comparisons of tearing energies estimated from known load cases and those obtained by finite element analysis for candidate dimensions are presented. The metal layers of bellows are subject to an out-of-plane buckling instability for the case of external pressure loading; failure of this type was experimentally observed. The proposed structure also exhibits column instability when subject to internal pressure, as do metal bellows. For hoop-stack bellows, shear deflection cannot be ignored and this leads to column instability for both internal and external pressures, the latter being analogous to the case of tension buckling of a beam. During prototype bellows testing, transverse modes of vibration are believed to have been excited parametrically as a consequence of the oscillatory pressures. Some operating frequencies of interest in this study lie above the cut-on frequency at which Timoshenko beam theory (TBT) predicts multiple phase speeds; it is shown that TBT fails to accurately predict both mode shapes and resonance frequencies in this regime. TBT is also shown to predict multiple phase speeds in the presence of axial tension, or external pressures, at magnitudes of interest in this study, over the entire frequency spectrum. For modes below cut-on absent a pressure differential (or equivalently, axial load) TBT predicts decreasing resonance frequencies for both internal external static pressure, and converges on known, valid static buckling solutions. Parametric stability in the presence of oscillatory pressure is discussed for such modes; periodic solutions to the Whittaker-Hill equation are pursued to illustrate the shape of the parametric instability regions, and contrasted with results of the more well-known Mathieu equation.

Affective modulation of external misattribution bias in source monitoring in schizophrenia.

PubMed

Costafreda, S G; Brébion, G; Allen, P; McGuire, P K; Fu, C H Y

2008-06-01

Schizophrenic patients tend to attribute internal events to external agents, a bias that may be linked to positive symptoms. We investigated the effect of emotional valence on the cognitive bias. Male schizophrenic subjects (n=30) and an experimenter alternatively produced neutral and negative words. The subject then decided whether he or the experimenter had generated the item. External misattributions were more common than self-misattributions, and the bias was greater for patients with active hallucinations and delusions relative to patients in remission. Actively psychotic patients but not patients in remission were more likely to generate external misattributions with negative relative to neutral words. Affective modulation of the externalizing cognitive bias in source monitoring is evident in patients with hallucinations and delusions.

Buckling test of a 3-meter-diameter corrugated graphite-epoxy ring-stiffened cylinder

NASA Technical Reports Server (NTRS)

Davis, R. C.

1982-01-01

A three m diameter by three m long corrugated cylindrical shell with external stiffening rings was tested to failure by buckling. The corrugation geometry for the graphite epoxy composite cylinder wall was optimized to withstand a compressive load producing an ultimate load intensity of 157.6 kN/m without buckling. The test method used to produce the design load intensity was to mount the specimen as a cantilevered cylinder and apply a pure bending moment to the end. A load introduction problem with the specimen was solved by using the BOSOR 4 shell of revolution computer code to analyze the shell and attached loading fixtures. The cylinder test loading achieved was 101 percent of design ultimate, and the resulting mass per unit of shell wall area was 1.96 kg/sq m.

The Mechanochemical Cycle of Mammalian Kinesin-2 KIF3A/B under Load.

PubMed

Andreasson, Johan O L; Shastry, Shankar; Hancock, William O; Block, Steven M

2015-05-04

The response of motor proteins to external loads underlies their ability to work in teams and determines the net speed and directionality of cargo transport. The mammalian kinesin-2, KIF3A/B, is a heterotrimeric motor involved in intraflagellar transport and vesicle motility in neurons. Bidirectional cargo transport is known to result from the opposing activities of KIF3A/B and dynein bound to the same cargo, but the load-dependent properties of kinesin-2 are poorly understood. We used a feedback-controlled optical trap to probe the velocity, run length, and unbinding kinetics of mouse KIF3A/B under various loads and nucleotide conditions. The kinesin-2 motor velocity is less sensitive than kinesin-1 to external forces, but its processivity diminishes steeply with load, and the motor was observed occasionally to slip and reattach. Each motor domain was characterized by studying homodimeric constructs, and a global fit to the data resulted in a comprehensive pathway that quantifies the principal force-dependent kinetic transitions. The properties of the KIF3A/B heterodimer are intermediate between the two homodimers, and the distinct load-dependent behavior is attributable to the properties of the motor domains and not to the neck linkers or the coiled-coil stalk. We conclude that the force-dependent movement of KIF3A/B differs significantly from conventional kinesin-1. Against opposing dynein forces, KIF3A/B motors are predicted to rapidly unbind and rebind, resulting in qualitatively different transport behavior from kinesin-1. Copyright © 2015 Elsevier Ltd. All rights reserved.

The mechanochemical cycle of mammalian kinesin-2 KIF3A/B under load

PubMed Central

Andreasson, Johan O.L.; Shastry, Shankar; Hancock, William O.; Block, Steven M.

2015-01-01

Summary The response of motor proteins to external loads underlies their ability to work in teams and determines the net speed and directionality of cargo transport. The mammalian kinesin-2, KIF3A/B, is a heterotrimeric motor involved in intraflagellar transport and vesicle motility in neurons. Bidirectional cargo transport is known to result from the opposing activities of KIF3A/B and dynein bound to the same cargo, but the load-dependent properties of kinesin-2 are poorly understood. We used a feedback-controlled optical trap to probe the velocity, run length and unbinding kinetics of mouse KIF3A/B under various loads and nucleotide conditions. The kinesin-2 motor velocity is less sensitive than kinesin-1 to external forces, but its processivity diminishes steeply with load, and the motor was observed occasionally to slip and reattach. Each motor domain was characterized by studying homodimeric constructs, and a global fit to the data resulted in a comprehensive pathway that quantifies the principal force-dependent kinetic transitions. The properties of the KIF3A/B heterodimer are intermediate between the two homodimers, and the distinct load-dependent behavior is attributable to the properties of the motor domains, and not to the neck-linkers or the coiled-coil stalk. We conclude that the force-dependent movement of KIF3A/B differs significantly from conventional kinesin-1. Against opposing dynein forces, KIF3A/B motors are predicted to rapidly unbind and rebind, resulting in qualitatively different transport behavior from kinesin-1. PMID:25866395

Demolition of a hospital building by controlled explosion: the impact on filamentous fungal load in internal and external air.

PubMed

Bouza, E; Peláez, T; Pérez-Molina, J; Marín, M; Alcalá, L; Padilla, B; Muñoz, P; Adán, P; Bové, B; Bueno, M J; Grande, F; Puente, D; Rodríguez, M P; Rodríguez-Créixems, M; Vigil, D; Cuevas, O

2002-12-01

The demolition of a maternity building at our institution provided us with the opportunity to study the load of filamentous fungi in the air. External (nearby streets) and internal (within the hospital buildings) air was sampled with an automatic volumetric machine (MAS-100 Air Samplair) at least daily during the week before the demolition, at 10, 30, 60, 90,120, 180, 240, 420, 540 and 660 min post-demolition, daily during the week after the demolition and weekly during weeks 2, 3 and 4 after demolition. Samples were duplicated to analyse reproducibility. Three hundred and forty samples were obtained: 115 external air, 69 'non-protected' internal air and 156 protected internal air [high efficiency particulate air (HEPA) filtered air under positive pressure]. A significant increase in the colony count of filamentous fungi occurred after the demolition. Median colony counts of external air on demolition day were significantly higher than from internal air (70.2 cfu/m(3) vs 35.8 cfu/m(3)) (P < 0.001). Mechanical demolition on day +4 also produced a significant difference between external and internal air (74.5 cfu/m(3) vs 41.7 cfu/m(3)). The counts returned to baseline levels on day +11. Most areas with a protected air supply yielded no colonies before demolition day and remained negative on demolition day. The reproducibility of the count method was good (intra-assay variance: 2.4 cfu/m(3)). No episodes of invasive filamentous mycosis were detected during the three months following the demolition. Demolition work was associated with a significant increase in the fungal colony counts of hospital external and non-protected internal air. Effective protective measures may be taken to avoid the emergence of clinical infections. Copyright 2002 The Hospital Infection Society

Characterizing the Anomalous Cognition-Emotion Interactions in Externalizing

PubMed Central

Baskin-Sommers, Arielle R.; Curtin, John J.; Larson, Christine L.; Stout, Daniel; Kiehl, Kent A.; Newman, Joseph P.

2012-01-01

Externalizing traits are characterized by exaggerated emotional (e.g., frustration, anger) and behavioral (e.g., drug seeking, reactive aggression) reactions to motivationally-significant stimuli. Explanations for this exaggerated reactivity emphasize attention, executive function, and affective processes, but the associations among these processes is rarely investigated. To examine these interactions, we measure fear potentiated startle (FPS; Experiment 1) and neural activation (Experiment 2) in an instructed fear paradigm that manipulates attentional focus, demands on executive functioning, and emotion. In both studies, exaggerated emotional reactivity associated with externalizing was specific to conditions that focused attention on threat information and placed minimal demands on executive functioning. Results suggest that a crucial cognition-emotion interaction affecting externalizing is the over-prioritization and over-allocation of attention to motivationally-significant information, which in turn, may impair executive and affective regulation. PMID:22579718

What Strains the Anterior Cruciate Ligament During a Pivot Landing?

PubMed Central

Oh, Youkeun K.; Lipps, David B.; Ashton-Miller, James A.; Wojtys, Edward M.

2015-01-01

Background The relative contributions of an axial tibial torque and frontal plane moment to anterior cruciate ligament (ACL) strain during pivot landings are unknown. Hypothesis The peak normalized relative strain in the anteromedial (AM) bundle of the ACL is affected by the direction of the axial tibial torque but not by the direction of the frontal plane moment applied concurrently during a simulated jump landing. Study Design Controlled and descriptive laboratory studies. Methods Fifteen adult male knees with pretensioned knee muscle-tendon unit forces were loaded under a simulated pivot landing test. Compression, flexion moment, internal or external tibial torque, and knee varus or valgus moment were simultaneously applied to the distal tibia while recording the 3D knee loads and tibiofemoral kinematics. The AM-ACL relative strain was measured using a 3-mm differential variable reluctance transducer. The results were analyzed using nonparametric Wilcoxon signed–rank tests. A 3D dynamic biomechanical knee model was developed using ADAMS and validated to help interpret the experimental results. Results The mean (SD) peak AM-ACL relative strain was 192% greater (P <.001) under the internal tibial torque combined with a knee varus or valgus moment (7.0% [3.9%] and 7.0% [4.1%], respectively) than under external tibial torque with the same moments (2.4% [2.5%] and 2.4% [3.2%], respectively). The knee valgus moment augmented the AM-ACL strain due to the slope of the tibial plateau inducing mechanical coupling (ie, internal tibial rotation and knee valgus moment); this augmentation occurred before medial knee joint space opening. Conclusion An internal tibial torque combined with a knee valgus moment is the worst-case ACL loading condition. However, it is the internal tibial torque that primarily causes large ACL strain. Clinical Relevance Limiting the maximum coefficient of friction between the shoe and playing surface should limit the peak internal tibial torque that can be applied to the knee during jump landings, thereby reducing peak ACL strain and the risk for noncontact injury. PMID:22223717

Failure Analysis of a Helicopter External Fuel-Tank Pylon

NASA Technical Reports Server (NTRS)

Newman, John A.; Piascik, Robert S.; Lindenberg, Richard A.

2002-01-01

An eight-inch-long (0.2 m) crack was found in an external fuel-tank pylon of a U.S. Coast Guard HH-60 helicopter. The damaged pylon was removed from service and destructively examined at NASA Langley Research Center (LaRC) to determine the cause of the crack. Results of the analysis revealed that crack initiation occurred at corrosion pits in a fastener hole and crack propagation was a result of cyclic loading.

Investigation into the Fatigue Crack Initiation Process in Metals.

DTIC Science & Technology

1985-12-01

fatigue crack initiation in metals under spectrum loading is described. The work focuses on the microplastic deformation properties of a surface...behavior is then controlled by the external load spectra, but is greatly influenced by the reaction stresses within a microplastic grain generated when its...49 4.7 Example values of strain just outside microplastic grains indicating an elastic matrix and deformation depths around 10 n - the typical

Mathematical Model of Bone Regeneration in a Porous Implant

NASA Astrophysics Data System (ADS)

Maslov, L. B.

2017-07-01

A mathematical model of the reparative regeneration of bone tissue governed by the law of cell differentiation and action of an external periodic mechanical loading is presented. The model allows one to study the recovery processes of injured human locomotor system elements under a dynamic loading and to theoretically substantiate the choice of an optimum periodic impact on the defective tissues for their fastest and steady healing.

Elastic-plastic analysis of annular plate problems using NASTRAN

NASA Technical Reports Server (NTRS)

Chen, P. C. T.

1983-01-01

The plate elements of the NASTRAN code are used to analyze two annular plate problems loaded beyond the elastic limit. The first problem is an elastic-plastic annular plate loaded externally by two concentrated forces. The second problem is stressed radially by uniform internal pressure for which an exact analytical solution is available. A comparison of the two approaches together with an assessment of the NASTRAN code is given.

Structures Flight Test Handbook

DTIC Science & Technology

1990-11-01

landing gear and must absorb most of the shock of the landing impact (hydraulically or pneumatically) as well as provide a means of stopping the plane...amount of energy a material car. absorb elastically in a unit volume of the material. Strength - ability to withstand external loads without failure...Toughness - total energy absorbed before failure occurs. NOMENCLATURE A cross-sectional area DLL design limit load E Young’s Modulus e strain FEM

Rehabilitation of Delavan Lake, Wisconsin

USGS Publications Warehouse

Robertson, Dale M.; Goddard, Gerald L.; Helsel, D.R.; MacKinnon, Kevin L.

2009-01-01

A comprehensive rehabilitation plan was developed and implemented to shift Delavan Lake, Wisconsin, from a hypereutrophic to a mesotrophic condition. The plan was threefold: (1) reduce external phosphorus (P) loading by applying Best Management Practices in the watershed, enhance an existing wetland, and short-circuit the inflows through the lake, (2) reduce internal P loading by treating the sediments with alum and removing carp, and (3) rehabilitate the fishery by removing carp and bigmouth buffalo and adding piscivores (biomanipulation). The first and second parts of the plan met with only limited success. With only minor reductions in internal and external P loading, P concentrations in the lake returned to near pre-treatment concentrations. The intensive biomanipulation and resulting trophic cascade (increased piscivores, decreased planktivores, increased large zooplankton populations, and reduced phytoplankton populations) eliminated most of the original problems in the lake (blue-green algal blooms and limited water clarity). However, now there is extensive macrophyte growth and abundant filamentous algae. Without significantly reducing the sources of the problems (high P loading) in Delavan Lake, the increased water clarity may not last. With an improved understanding of the individual components of this rehabilitation program, better future management plans can be developed for Delavan Lake and other lakes and reservoirs with similar eutrophication problems.

Suitability of Biomorphic Silicon Carbide Ceramics as Drug Delivery Systems against Bacterial Biofilms

PubMed Central

Díaz-Rodríguez, P.; Pérez-Estévez, A.; Seoane, R.; González, P.; Serra, J.; Landin, M.

2013-01-01

The present work is aimed at getting a new insight into biomorphic silicon carbides (bioSiCs) as bone replacement materials. BioSiCs from a variety of precursors were produced, characterized, and loaded with a broad-spectrum antibiotic. The capacity of loaded bioSiCs for preventing and/or treating preformed S. aureus biofilms has been studied. The differences in precursor characteristics are maintained after the ceramic production process. All bioSiCs allow the loading process by capillarity, giving loaded materials with drug release profiles dependent on their microstructure. The amount of antibiotic released in liquid medium during the first six hours depends on bioSiC porosity, but it could exceed the minimum inhibitory concentration of Staphylococcus aureus, for all the materials studied, thus preventing the proliferation of bacteria. Differences in the external surface and the number and size of open external pores of bioSiCs contribute towards the variations in the effect against bacteria when experiments are carried out using solid media. The internal structure and surface properties of all the systems seem to facilitate the therapeutic activity of the antibiotic on the preformed biofilms, reducing the number of viable bacteria present in the biofilm compared to controls. PMID:23936680

Nondestructive Estimation of Muscle Contributions to STS Training with Different Loadings Based on Wearable Sensor System

PubMed Central

2018-01-01

Partial body weight support or loading sit-to-stand (STS) rehabilitation can be useful for persons with lower limb dysfunction to achieve movement again based on the internal residual muscle force and external assistance. To explicate how the muscles contribute to the kinetics and kinematics of STS performance by non-invasive in vitro detection and to nondestructively estimate the muscle contributions to STS training with different loadings, a wearable sensor system was developed with ground reaction force (GRF) platforms, motion capture inertial sensors and electromyography (EMG) sensors. To estimate the internal moments of hip, knee and ankle joints and quantify the contributions of individual muscle and gravity to STS movement, the inverse dynamics analysis on a simplified STS biomechanical model with external loading is proposed. The functional roles of the lower limb individual muscles (rectus femoris (RF), gluteus maximus (GM), vastus lateralis (VL), tibialis anterior (TA) and gastrocnemius (GAST)) during STS motion and the mechanism of the muscles’ synergies to perform STS-specific subtasks were analyzed. The muscle contributions to the biomechanical STS subtasks of vertical propulsion, anteroposterior (AP) braking and propulsion for body balance in the sagittal plane were quantified by experimental studies with EMG, kinematic and kinetic data. PMID:29587391

Nondestructive Estimation of Muscle Contributions to STS Training with Different Loadings Based on Wearable Sensor System.

PubMed

Liu, Kun; Liu, Yong; Yan, Jianchao; Sun, Zhenyuan

2018-03-25

Partial body weight support or loading sit-to-stand (STS) rehabilitation can be useful for persons with lower limb dysfunction to achieve movement again based on the internal residual muscle force and external assistance. To explicate how the muscles contribute to the kinetics and kinematics of STS performance by non-invasive in vitro detection and to nondestructively estimate the muscle contributions to STS training with different loadings, a wearable sensor system was developed with ground reaction force (GRF) platforms, motion capture inertial sensors and electromyography (EMG) sensors. To estimate the internal moments of hip, knee and ankle joints and quantify the contributions of individual muscle and gravity to STS movement, the inverse dynamics analysis on a simplified STS biomechanical model with external loading is proposed. The functional roles of the lower limb individual muscles (rectus femoris (RF), gluteus maximus (GM), vastus lateralis (VL), tibialis anterior (TA) and gastrocnemius (GAST)) during STS motion and the mechanism of the muscles' synergies to perform STS-specific subtasks were analyzed. The muscle contributions to the biomechanical STS subtasks of vertical propulsion, anteroposterior (AP) braking and propulsion for body balance in the sagittal plane were quantified by experimental studies with EMG, kinematic and kinetic data.

Doxycycline hyclate-loaded bleached shellac in situ forming microparticle for intraperiodontal pocket local delivery.

PubMed

Phaechamud, Thawatchai; Chanyaboonsub, Nuttapong; Setthajindalert, Orn

2016-10-10

Bleached shellac (BS) is a water-insoluble polyester resin made up of sesquiterpenoid acids esterified with hydroxy aliphatic acids. In this study, BS dissolved in N-methyl pyrrolidone (NMP), dimethyl sulfoxide (DMSO) and 2-pyrrolidone was used as the internal phase of oil in oil emulsion using olive oil emulsified with glyceryl monostearate (GMS) as the external phase of in situ forming microparticles (ISM). Doxycycline hyclate (DH)-loaded BS ISMs were tested for emulsion stability, viscosity, rheology, transformation into microparticles, syringeability, drug release, surface topography, in vitro degradation and antimicrobial activities against Staphylococcus aureus, Streptococcus mutans and Porphyromonas gingivalis. All emulsions exhibited pseudoplastic flow and notably low syringeability force. Slower transformation from emulsion into microparticles of ISM prepared with 2-pyrrolidone was owing to slower solvent exchange of this solvent which promoted less porous structure of obtained BS matrix microparticles. The system containing 2-pyrrolidone exhibited a higher degradability than that prepared with DMSO. Developed DH-loaded BS ISMs exhibited a sustainable drug release for 47days with Fickian diffusion and effectively inhibited P. gingivalis, S. mutans and S. aureus. Therefore a DH-loaded BS ISM using olive oil containing GMS as the external phase and 2-pyrrolidone as a solvent was a suitable formulation for periodontitis treatment. Copyright © 2016 Elsevier B.V. All rights reserved.

The contribution of working memory to divided attention.

PubMed

Santangelo, Valerio; Macaluso, Emiliano

2013-01-01

Previous studies have indicated that increasing working memory (WM) load can affect the attentional selection of signals originating from one object/location. Here we assessed whether WM load affects also the selection of multiple objects/locations (divided attention). Participants monitored either two object-categories (vs. one category; object-based divided attention) or two locations (vs. one location; space-based divided attention) while maintaining in WM either a variable number of objects (object-based WM load) or locations (space-based WM load). Behavioural results showed that WM load affected attentional performance irrespective of divided or focused attention. However, fMRI results showed that the activity associated with object-based divided attention increased linearly with increasing object-based WM load in the left and right intraparietal sulcus (IPS); while, in the same areas, activity associated with space-based divided attention was not affected by any type of WM load. These findings support the hypothesis that WM contributes to the maintenance of resource-demanding attentional sets in a domain-specific manner. Moreover, the dissociable impact of WM load on performance and brain activity suggests that increased IPS activation reflects a recruitment of additional, domain-specific processing resources that enable dual-task performance under conditions of high WM load and high attentional demand. Copyright © 2011 Wiley Periodicals, Inc.

Electric vehicle system for charging and supplying electrical power

DOEpatents

Su, Gui Jia

2010-06-08

A power system that provides power between an energy storage device, an external charging-source/load, an onboard electrical power generator, and a vehicle drive shaft. The power system has at least one energy storage device electrically connected across a dc bus, at least one filter capacitor leg having at least one filter capacitor electrically connected across the dc bus, at least one power inverter/converter electrically connected across the dc bus, and at least one multiphase motor/generator having stator windings electrically connected at one end to form a neutral point and electrically connected on the other end to one of the power inverter/converters. A charging-sourcing selection socket is electrically connected to the neutral points and the external charging-source/load. At least one electronics controller is electrically connected to the charging-sourcing selection socket and at least one power inverter/converter. The switch legs in each of the inverter/converters selected by the charging-source/load socket collectively function as a single switch leg. The motor/generators function as an inductor.

BUCLASP 3: A computer program for stresses and buckling of heated composite stiffened panels and other structures, user's manual

NASA Technical Reports Server (NTRS)

Tripp, L. L.; Tamekuni, M.; Viswanathan, A. V.

1973-01-01

The use of the computer program BUCLASP3 is described. The code is intended for thermal stress and instability analyses of structures such as unidirectionally stiffened panels. There are two types of instability analyses that can be effected by PAINT; (1) thermal buckling, and (2) buckling due to a specified inplane biaxial loading. Any structure that has a constant cross section in one direction, that may be idealized as an assemblage of beam elements and laminated flat and curved plate strip-elements can be analyzed. The two parallel ends of the panel must be simply supported, whereas arbitrary elastic boundary conditions may be imposed along any one or both external longitudinal side. Any variation in the temperature rise (from ambient) through the cross section of a panel is considered in the analyses but it must be assumed that in the longitudinal direction the temperature field is constant. Load distributions for the externally applied inplane biaxial loads are similar in nature to the permissible temperature field.

Inertial frictional ratchets and their load bearing efficiencies

NASA Astrophysics Data System (ADS)

Kharkongor, D.; Reenbohn, W. L.; Mahato, Mangal C.

2018-03-01

We investigate the performance of an inertial frictional ratchet in a sinusoidal potential driven by a sinusoidal external field. The dependence of the performance on the parameters of the sinusoidally varying friction, such as the mean friction coefficient and its phase difference with the potential, is studied in detail. Interestingly, under certain circumstances, the thermodynamic efficiency of the ratchet against an applied load shows a non-monotonic behaviour as a function of the mean friction coefficient. Also, in the large friction ranges, the efficiency is shown to increase with increasing applied load even though the corresponding ratchet current decreases as the applied load increases. These counterintuitive numerical results are explained in the text.

Stress-intensity factors and crack-opening displacements for round compact specimens. [fracture toughness of metallic materials

NASA Technical Reports Server (NTRS)

Newman, J. C., Jr.

1979-01-01

A two dimensional, boundary collocation stress analysis was used to analyze various round compact specimens. The influence of the round external boundary and of pin-loaded holes on stress intensity factors and crack opening displacements was determined as a function of crack-length-to-specimen-width ratios. A wide-range equation for the stress intensity factors was developed. Equations for crack-surface displacements and load-point displacements were also developed. In addition, stress intensity factors were calculated from compliance methods to demonstrate that load-displacement records must be made at the loading points and not along the crack line for crack-length-to-specimen-width ratios less than about 0.4.

Elastic-Plastic Finite Element Analysis of Fatigue Crack Growth in Mode 1 and Mode 2 Conditions

NASA Technical Reports Server (NTRS)

Nakagaki, M.; Atluri, S. N.

1978-01-01

Presented is an alternate cost-efficient and accurate elastic-plastic finite element procedure to analyze fatigue crack closure and its effects under general spectrum loading. Both Modes 1 and 2 type cycling loadings are considered. Also presented are the results of an investigation, using the newly developed procedure, of various factors that cause crack growth acceleration or retardation and delay effects under high-to-low, low-to-high, single overload, and constant amplitude type cyclic loading in a Mode 1 situation. Further, the results of an investigation of a centercracked panel under external pure shear (Mode 2) cyclic loading, of constant amplitude, are reported.

Simplified Design Method for Tension Fasteners

NASA Astrophysics Data System (ADS)

Olmstead, Jim; Barker, Paul; Vandersluis, Jonathan

2012-07-01

Tension fastened joints design has traditionally been an iterative tradeoff between separation and strength requirements. This paper presents equations for the maximum external load that a fastened joint can support and the optimal preload to achieve this load. The equations, based on linear joint theory, account for separation and strength safety factors and variations in joint geometry, materials, preload, load-plane factor and thermal loading. The strength-normalized versions of the equations are applicable to any fastener and can be plotted to create a "Fastener Design Space", FDS. Any combination of preload and tension that falls within the FDS represents a safe joint design. The equation for the FDS apex represents the optimal preload and load capacity of a set of joints. The method can be used for preliminary design or to evaluate multiple pre-existing joints.

49 CFR 178.346-4 - Outlets.

Code of Federal Regulations, 2010 CFR

2010-10-01

... must conform to § 178.345-11 and this section. (b) External self-closing stop-valves are not authorized as an alternative to internal self-closing stop-valves on loading/unloading outlets. [Amdt. 178-89...

49 CFR 195.110 - External loads.

Code of Federal Regulations, 2010 CFR

2010-10-01

..., vibration, thermal expansion, and contraction must be provided for in designing a pipeline system. In providing for expansion and flexibility, section 419 of ASME/ANSI B31.4 must be followed. (b) The pipe and...

49 CFR 195.110 - External loads.

Code of Federal Regulations, 2011 CFR

2011-10-01

..., vibration, thermal expansion, and contraction must be provided for in designing a pipeline system. In providing for expansion and flexibility, section 419 of ASME/ANSI B31.4 must be followed. (b) The pipe and...

Growth Control and Disease Mechanisms in Computational Embryogeny

NASA Technical Reports Server (NTRS)

Shapiro, Andrew A.; Yogev, Or; Antonsson, Erik K.

2008-01-01

This paper presents novel approach to applying growth control and diseases mechanisms in computational embryogeny. Our method, which mimics fundamental processes from biology, enables individuals to reach maturity in a controlled process through a stochastic environment. Three different mechanisms were implemented; disease mechanisms, gene suppression, and thermodynamic balancing. This approach was integrated as part of a structural evolutionary model. The model evolved continuum 3-D structures which support an external load. By using these mechanisms we were able to evolve individuals that reached a fixed size limit through the growth process. The growth process was an integral part of the complete development process. The size of the individuals was determined purely by the evolutionary process where different individuals matured to different sizes. Individuals which evolved with these characteristics have been found to be very robust for supporting a wide range of external loads.

Visual display and alarm system for wind tunnel static and dynamic loads

NASA Technical Reports Server (NTRS)

Hanly, Richard D.; Fogarty, James T.

1987-01-01

A wind tunnel balance monitor and alarm system developed at NASA Ames Research Center will produce several beneficial results. The costs of wind tunnel delays because of inadvertent balance damage and the costs of balance repair or replacement can be greatly reduced or eliminated with better real-time information on the balance static and dynamic loading. The wind tunnel itself will have enhanced utility with the elimination of overly cautious limits on test conditions. The microprocessor-based system features automatic scaling and 16 multicolored LED bargraphs to indicate both static and dynamic components of the signals from eight individual channels. Five individually programmable alarm levels are available with relay closures for internal or external visual and audible warning devices and other functions such as automatic activation of external recording devices, model positioning mechanisms, or tunnel shutdown.

Visual display and alarm system for wind tunnel static and dynamic loads

NASA Technical Reports Server (NTRS)

Hanly, Richard D.; Fogarty, James T.

1987-01-01

A wind tunnel balance monitor and alarm system developed at NASA Ames Research Center will produce several beneficial results. The costs of wind tunnel delays because of inadvertent balance damage and the costs of balance repair or replacement can be greatly reduced or eliminated with better real-time information on the balance static and dynamic loading. The wind tunnel itself will have enhanced utility with the elimination of overly cautious limits on test conditions. The microprocessor-based system features automatic scaling and 16 multicolored LED bargraphs to indicate both static and dynamic components of the signals from eight individual channels. Five individually programmable alarm levels are available with relay closures for internal or external visual and audible warning devices and other functions such as automatic activation of external recording devices, model positioning mechanism, or tunnel shutdown.

A thermoelastic transversely isotropic thick walled cylinder/disk application: An analytical solution and study

NASA Technical Reports Server (NTRS)

Arnold, S. M.

1989-01-01

A continuum theory is utilized to represent the thermoelastic behavior of a thick walled composite cylinder that can be idealized as transversely isotropic. A multiaxial statement of the constitutive theory employed is presented, as well as the out of the plane of isotropy, plane stress, and plane strain reductions. The derived analytical solution presented is valid for a cylindrical tube or thin disk with a concentric hole, subjected to internal and/or external pressure and a general radial temperature distribution. A specific problem examined is that of a thick walled cylinder subjected to an internal and external pressure loading and a linear radial temperature distribution. The results are expressed in nondimensional form and the effects on the response behavior are examined for various material properties, fiber orientation and types of loadings.

Energy Management Policies in Distributed Residential Energy Systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Duan, Sisi; Sun, Jingtao

2016-01-01

In this paper, we study energy management problems in communities with several neighborhood-level Residential Energy Systems (RESs). We consider control problems from both community level and residential level to handle external changes such as restriction on peak demand and restriction on the total demand from the electricity grid. We propose three policies to handle the problems at community level. Based on the collected data from RESs such as predicted energy load, the community controller analyzes the policies, distribute the results to the RES, and each RES can then control and schedule its own energy load based on different coordination functions.more » We utilize a framework to integrate both policy analysis and coordination of functions. With the use of our approach, we show that the policies are useful to resolve the challenges of energy management under external changes.« less

External heat transfer predictions in a highly loaded transonic linear turbine guide vane cascade using an upwind biased Navier-Stokes solver

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gehrer, A.; Jericha, H.

External heat transfer predictions are performed for two-dimensional turbine blade cascades. The Reynolds-averaged Navier-Stokes equations with algebraic (Arnone and Pacciani, 1998), one-equation (Spalart and Allmaras, 1994), and two-equation (low-Re {kappa}-{epsilon}, Biswas and Fukuyama, 1994) turbulence closures are solved with a fully implicit time-marching finite volume method. Comparisons with measurements (Arts et al., 1990; Arts, 1994) for a highly loaded transonic turbine nozzle guide vane cascade show good agreement in some cases, but also reveal problems with transition prediction and turbulence modeling. Special attention has been focused on the low-Re {kappa}-{epsilon} model concerning the influence of the inlet boundary condition formore » the {epsilon}-equation and problems in the stagnation point region.« less

The superficial medial collateral ligament is the primary medial restraint to knee laxity after cruciate-retaining or posterior-stabilised total knee arthroplasty: effects of implant type and partial release.

PubMed

Athwal, Kiron K; Daou, Hadi El; Kittl, Christoph; Davies, Andrew J; Deehan, David J; Amis, Andrew A

2016-08-01

The aim of this study was to quantify the contributions of medial soft tissues to stability following cruciate-retaining (CR) or posterior-stabilised (PS) total knee arthroplasty (TKA). Using a robotic system, eight cadaveric knees were subjected to ±90-N anterior-posterior force, ±5-Nm internal-external and ±8-Nm varus-valgus torques at various flexion angles. The knees were tested intact and then with CR and PS implants, and successive cuts of the deep and superficial medial collateral ligaments (dMCL, sMCL) and posteromedial capsule (PMC) quantified the percentage contributions of each structure to restraining the applied loads. In implanted knees, the sMCL restrained valgus rotation (62 % across flexion angles), anterior-posterior drawer (24 and 10 %, respectively) and internal-external rotation (22 and 37 %). Changing from CR TKA to PS TKA increased the load on the sMCL when resisting valgus loads. The dMCL restrained 11 % of external and 13 % of valgus rotations, and the PMC was significant at low flexion angles. This work has shown that medial release in the varus knee should be minimised, as it may inadvertently result in a combined laxity pattern. There is increasing interest in preserving constitutional varus in TKA, and this work argues for preservation of the sMCL to afford the surgeon consistent restraint and maintain a balanced knee for the patient.