Extraordinary Matter: Visualizing Space Plasmas and Particles
NASA Astrophysics Data System (ADS)
Barbier, S. B.; Bartolone, L.; Christian, E. R.; Eastman, T.; Lewis, E.; Thieman, J.
2010-08-01
We present an online NASA multimedia library, now in development, designed to assist educators with explaining concepts of basic particle and plasma physics. Such resources are few in number and/or difficult to locate, and most do not provide suitable context. On our Extraordinary Matter site, each product will be accompanied by an explanation at a reading level matching the concept's educational level, link to the source, educational standards addressed, file size, use restrictions, credits, format(s), creation date and, optionally, associated educational activities and other relevant information and links. The site will target grades 9-14 and the equivalent in informal education and outreach. Products are intended to stand alone, making them adaptable to the widest range of uses. This project is funded by the NASA EPOESS Program in response to NRA NNH08ZDA001N for ROSES-2008.
Extraordinary Matter: Visualizing Space Plasmas and Particles
NASA Astrophysics Data System (ADS)
Barbier, S. B.; Bartolone, L.; Christian, E.; Thieman, J.; Eastman, T.; Lewis, E.
2011-09-01
Atoms and sub-atomic particles play a crucial role in the dynamics of our universe, but these particles and the space plasmas comprised of them are often overlooked in popular scientific and educational resources. Although the concepts are pertinent to a wide range of topics, even the most basic particle and plasma physics principles are generally unfamiliar to non-scientists. Educators and public communicators need assistance in explaining these concepts that cannot be easily demonstrated in the everyday world. Active visuals are a highly effective aid to understanding, but resources of this type are currently few in number and difficult to find, and most do not provide suitable context for audience comprehension. To address this need, our team is developing an online multimedia reference library of animations, visualizations, interactivities, and videos resources - Extraordinary Matter: Visualizing Space Plasmas and Particles. The site targets grades 9-14 and the equivalent in informal education and public outreach. Each ready-to-use product will be accompanied by a supporting explanation at a reading level matching the educational level of the concept. It will also have information on relevant science, technology, engineering, and mathematics (STEM) educational standards, activities, lesson plans, related products, links, and suggested uses. These products are intended to stand alone, making them adaptable to the widest range of uses, including scientist presentations, museum displays, educational websites and CDs, teacher professional development, and classroom use. This project is funded by a NASA Education and Public Outreach in Earth and Space Science (EPOESS) grant.
7 CFR 1773.41 - Extraordinary retirement losses.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 7 Agriculture 12 2010-01-01 2010-01-01 false Extraordinary retirement losses. 1773.41 Section 1773... Documentation § 1773.41 Extraordinary retirement losses. The CPA's workpapers must contain an analysis of retirement losses, including any required approval by a regulatory commission with jurisdiction in the matter...
Visualizing Space Plasmas and Particles: Extraordinary Matter
NASA Astrophysics Data System (ADS)
Barbier, B.; Bartolone, L. M.; Christian, E. R.; Eastman, T. E.; Lewis, E.; Thieman, J. R.
2010-12-01
A recent survey of museum visitors documented some startling misconceptions at a very basic level. Even in this "science attentive" group, one quarter of the respondents believed that an atom would explode if it lost an electron, one sixth said it would become a new atom or element, and one fifth said they had no idea what would happen. Only one fourth of the respondents indicated they were familiar with plasma as a state of matter. Current resources on these topics are few in number and/or are difficult to locate, and they rarely provide suitable context at a level understandable to high school students and educators or to the interested public. In response to this and other evidence of common misunderstandings of simple particle and plasma science, our team of space scientists and education specialists has embarked upon the development of "Extraordinary Matter: Visualizing Space Plasmas and Particles", an online NASA multimedia library. It is designed to assist formal and informal educators and scientists with explaining concepts that cannot be easily demonstrated in the everyday world. The newly released site, with a target audience equivalent to grades 9-14, includes both existing products, reviewed by our team for quality, and new products we have developed. Addition of products to our site is in large part determined by the results of our front-end evaluation to determine the specific needs, gaps, and priorities of potential audiences. Each ready-to-use product is accompanied by a supporting explanation at a reading level matching the educational level of the concept, along with educational standards addressed, and links to other associated resources. Some will include related educational activities. Products are intended to stand alone, making them adaptable to the widest range of uses, either individually or as a custom-selected group. Uses may include, for example, scientist presentations, museum displays, teacher professional development, and classroom applications. Visitors will be able to view the site with our first major development products, and they can sign up to receive periodic email updates.
Extraordinary Matter: Visualizing Space Plasmas and Particles
NASA Astrophysics Data System (ADS)
Barbier, B.; Bartolone, L. M.; Christian, E. R.; Eastman, T. E.; Lewis, E.; Thieman, J. R.
2009-12-01
Atoms and sub-atomic particles play a crucial role in the dynamics of our universe, but these particles and the space plasmas comprised of such particles are often overlooked in popular scientific and educational resources. Even the most basic particle and plasma physics principles are generally unfamiliar to non-scientists. Educators and public communicators need assistance in explaining these concepts that cannot be easily demonstrated in the everyday world. Active visuals are a highly effective aid to understanding, but resources of this type are currently few in number and difficult to find, and most do not provide suitable context for audience comprehension. To address this need, our team of space science educators and scientists from NASA Goddard Space Flight Center and the Adler Planetarium are in the process of developing an online multimedia reference library of resources such as animations, visualizations, interactivities, videos, etc. This website, Extraordinary Matter: Visualizing Space Plasmas and Particles, is designed to assist educators with explaining these concepts that cannot be easily demonstrated in the everyday world. The site will target primarily grades 9-14 and the equivalent in informal education and public outreach. Each ready-to-use product will be accompanied by a supporting explanation at a reading level matching the educational level of the concept. It will also have information on relevant STEM education standards, date of development, credits, restrictions on use, and possibly related products, links, and suggested uses. These products are intended to stand alone, making them adaptable to the widest range of uses, including scientist presentations, museum displays, educational websites and CDs, teacher professional development, and classroom use. Our team has surveyed the potential user community for their specific needs, gaps, and priorities. Referencing STEM educational standards, we are accumulating and enhancing the best available existing materials, and we have concurrently begun the development of new products to fill remaining gaps. We are focusing initially on the simplest concepts and gradually moving on to the more complex, because simpler concepts apply to a wider range of space science, from heliophysics and astrophysics to technology and human exploration. Visitors to the poster will have the opportunity to provide input and sign up to receive periodic email updates on the status of the website.
An RGB approach to extraordinary spectra
NASA Astrophysics Data System (ADS)
Grusche, Sascha; Theilmann, Florian
2015-09-01
After Newton had explained a series of ordinary spectra and Goethe had pointed out its complementary counterpart, Nussbaumer discovered a series of extraordinary spectra which are geometrically identical and colourwise analogous to Newton’s and Goethe’s spectra. To understand the geometry and colours of extraordinary spectra, the wavelength composition is explored with filters and spectroscopic setups. Visualized in a dispersion diagram, the wavelength composition is interpreted in terms of additive colour mixing. Finally, all spectra are simulated as the superposition of red, green, and blue images that are shifted apart. This RGB approach makes it easy to understand the complex relationship between wavelengths and colours.
Functional imaging with cellular resolution reveals precise micro-architecture in visual cortex
NASA Astrophysics Data System (ADS)
Ohki, Kenichi; Chung, Sooyoung; Ch'ng, Yeang H.; Kara, Prakash; Reid, R. Clay
2005-02-01
Neurons in the cerebral cortex are organized into anatomical columns, with ensembles of cells arranged from the surface to the white matter. Within a column, neurons often share functional properties, such as selectivity for stimulus orientation; columns with distinct properties, such as different preferred orientations, tile the cortical surface in orderly patterns. This functional architecture was discovered with the relatively sparse sampling of microelectrode recordings. Optical imaging of membrane voltage or metabolic activity elucidated the overall geometry of functional maps, but is averaged over many cells (resolution >100µm). Consequently, the purity of functional domains and the precision of the borders between them could not be resolved. Here, we labelled thousands of neurons of the visual cortex with a calcium-sensitive indicator in vivo. We then imaged the activity of neuronal populations at single-cell resolution with two-photon microscopy up to a depth of 400µm. In rat primary visual cortex, neurons had robust orientation selectivity but there was no discernible local structure; neighbouring neurons often responded to different orientations. In area 18 of cat visual cortex, functional maps were organized at a fine scale. Neurons with opposite preferences for stimulus direction were segregated with extraordinary spatial precision in three dimensions, with columnar borders one to two cells wide. These results indicate that cortical maps can be built with single-cell precision.
NASA Astrophysics Data System (ADS)
Davies, Paul
2009-07-01
To a physicist, life seems little short of miraculous-all those stupid atoms getting together to perform such clever tricks! For centuries, living organisms were regarded as some sort of magic matter. Today, we know that no special "life force" is at work in biology; there is just ordinary matter doing extraordinary things, all the while obeying the familiar laws of physics. What, then, is the secret of life's remarkable properties?
The Dark Matter of Lab Work: Illuminating the Negotiation of Disciplined Perception in Mechanics
ERIC Educational Resources Information Center
Lindwall, Oskar; Lymer, Gustav
2008-01-01
This study examines the practical work of a pair of students and an instructor using probeware in a mechanics lab. The aim of the study is to describe and discuss a type of interactional sequence that we refer to as "dark matter", the ordinary backdrop to the extraordinary sequences that are easily recognizable as clear-cut instances of learning.…
Tressoldi, Patrizio E.
2011-01-01
Starting from the famous phrase “extraordinary claims require extraordinary evidence,” we will present the evidence supporting the concept that human visual perception may have non-local properties, in other words, that it may operate beyond the space and time constraints of sensory organs, in order to discuss which criteria can be used to define evidence as extraordinary. This evidence has been obtained from seven databases which are related to six different protocols used to test the reality and the functioning of non-local perception, analyzed using both a frequentist and a new Bayesian meta-analysis statistical procedure. According to a frequentist meta-analysis, the null hypothesis can be rejected for all six protocols even if the effect sizes range from 0.007 to 0.28. According to Bayesian meta-analysis, the Bayes factors provides strong evidence to support the alternative hypothesis (H1) over the null hypothesis (H0), but only for three out of the six protocols. We will discuss whether quantitative psychology can contribute to defining the criteria for the acceptance of new scientific ideas in order to avoid the inconclusive controversies between supporters and opponents. PMID:21713069
NASA Astrophysics Data System (ADS)
Coltelli, Mauro; Biale, Emilio; Ciancitto, Francesco; Pecora, Emilio; Prestifilippo, Michele
2014-05-01
Since 1994 a video-surveillance camera located on a peak just above the active volcanic vents of Stromboli island records the explosive activity of one of the few volcanoes on the world performing a persistent eruptive activity. From 2003, after one of the larger lava flow eruption of the last century, the video-surveillance system was enhanced with more stations having both thermal and visual cameras. The video-surveillance helps volcanologists to characterize the mild explosive activity of Stromboli named Strombolian and to distinguish between the frequent "ordinary" Strombolian explosions and the occasional "extraordinary" strong Strombolian explosions that periodically occur. A new class of extraordinary explosions was discovered filling the gap between the ordinary activity and the strong explosions named major explosions when the tephra fallout covers large areas on the volcano summit and paroxysmal ones when the bombs fall down to the inhabited area along the coast of the island. In order to quantify the trend of the ordinary Strombolian explosions and to understand the occurring of the extraordinary strong Strombolian explosions a computer assisted image analysis was developed to process the huge amount of thermal and visual images recorded in several years. The results of this complex analysis allow us to clarify the processes occurring in the upper plumbing system where the pockets/trains of bubbles coalesce and move into the active vent conduits producing the ordinary Strombolian activity, and to infer the process into the deeper part of the plumbing system where new magma supply and its evolution lead to the formation of the extraordinary strong Strombolian explosions.
Children's Encounters with Things: Schooling the Body
ERIC Educational Resources Information Center
Jones, Liz
2013-01-01
This article draws on work around matter and the material in order to examine how (extra)ordinary "things" are used to (re)produce formulaic and predictable performances within the context of an early years classroom. Using ethnographic data I focus on a series of encounters where oscillations between (in)animate objects and the child…
Making and Moving Publics: Stuart Hall's Projects, Maximal Selves and Education
ERIC Educational Resources Information Center
Roman, Leslie G.
2015-01-01
An extraordinary educator and public intellectual, Stuart Hall's career as a scholar, activist, teacher and mentor has touched almost every field in the social sciences and humanities. Paradoxically, education rarely claims him as an educator. Stuart Hall's refusal to see publics as given, fixed or settled matters with clear or final demarcations…
Prevocational Services: A Resource for Enhancing a Functional Academic Curriculum
ERIC Educational Resources Information Center
Miller, Jerry; Thompson, Elizabeth M.
2005-01-01
Developing appropriate prevocational services for students with visual impairments and additional severe disabilities presents a challenge. A recent pilot transition program acknowledged this difficulty by deciding that "the inclusion of students, who require an extraordinary amount of individual attention to learn skills, would detract from…
Digital visual communications using a Perceptual Components Architecture
NASA Technical Reports Server (NTRS)
Watson, Andrew B.
1991-01-01
The next era of space exploration will generate extraordinary volumes of image data, and management of this image data is beyond current technical capabilities. We propose a strategy for coding visual information that exploits the known properties of early human vision. This Perceptual Components Architecture codes images and image sequences in terms of discrete samples from limited bands of color, spatial frequency, orientation, and temporal frequency. This spatiotemporal pyramid offers efficiency (low bit rate), variable resolution, device independence, error-tolerance, and extensibility.
Fifteen years of cold matter on the atom chip: promise, realizations, and prospects
Keil, Mark; Amit, Omer; Zhou, Shuyu; Groswasser, David; Japha, Yonathan; Folman, Ron
2016-01-01
Here we review the field of atom chips in the context of Bose–Einstein Condensates (BEC) as well as cold matter in general. Twenty years after the first realization of the BEC and 15 years after the realization of the atom chip, the latter has been found to enable extraordinary feats: from producing BECs at a rate of several per second, through the realization of matter-wave interferometry, and all the way to novel probing of surfaces and new forces. In addition, technological applications are also being intensively pursued. This review will describe these developments and more, including new ideas which have not yet been realized. PMID:27499585
Retenation of soluble organic nutrients by a forested ecosystem
R.G. Qualls; B.L. Haines; Wayne T. Swank; S.W. Tyler
2002-01-01
We document an example of a forested watershed at the Coweeta Hydrologic Laboratory with an extraordinary tendency to retain dissolved organic matter (DOM) generated in large quantities within the ecosystem. Our objectives were to determine fluxes of dissolved organic C, N, and P (DOC,D ON, DOP, respectively), in water draining through each stratum of the ecosystem and...
Privatizing Education: Free School Policy in Sweden and England
ERIC Educational Resources Information Center
Wiborg, Susanne
2015-01-01
The aim of this article is to investigate why Sweden, the epitome of social democracy, has implemented education reforms leading to an extraordinary growth in Free Schools in contrast to liberal England, where Free School policy has been met with enormous resistance. Conventional wisdom would predict the contrary, but as a matter of fact Sweden…
Li, Wenjing; Li, Jianhong; Wang, Zhenchang; Li, Yong; Liu, Zhaohui; Yan, Fei; Xian, Junfang; He, Huiguang
2015-01-01
Previous studies have shown brain reorganizations after early deprivation of auditory sensory. However, changes of grey matter connectivity have not been investigated in prelingually deaf adolescents yet. In the present study, we aimed to investigate changes of grey matter connectivity within and between auditory, language and visual systems in prelingually deaf adolescents. We recruited 16 prelingually deaf adolescents and 16 age-and gender-matched normal controls, and extracted the grey matter volume as the structural characteristic from 14 regions of interest involved in auditory, language or visual processing to investigate the changes of grey matter connectivity within and between auditory, language and visual systems. Sparse inverse covariance estimation (SICE) was utilized to construct grey matter connectivity between these brain regions. The results show that prelingually deaf adolescents present weaker grey matter connectivity within auditory and visual systems, and connectivity between language and visual systems declined. Notably, significantly increased brain connectivity was found between auditory and visual systems in prelingually deaf adolescents. Our results indicate "cross-modal" plasticity after deprivation of the auditory input in prelingually deaf adolescents, especially between auditory and visual systems. Besides, auditory deprivation and visual deficits might affect the connectivity pattern within language and visual systems in prelingually deaf adolescents.
Elementary Visual Hallucinations and Their Relationships to Neural Pattern-Forming Mechanisms
ERIC Educational Resources Information Center
Billock, Vincent A.; Tsou, Brian H.
2012-01-01
An extraordinary variety of experimental (e.g., flicker, magnetic fields) and clinical (epilepsy, migraine) conditions give rise to a surprisingly common set of elementary hallucinations, including spots, geometric patterns, and jagged lines, some of which also have color, depth, motion, and texture. Many of these simple hallucinations fall into a…
Ultimate predators: lionfish have evolved to circumvent prey risk assessment abilities.
Lönnstedt, Oona M; McCormick, Mark I
2013-01-01
Invasive species cause catastrophic alterations to communities worldwide by changing the trophic balance within ecosystems. Ever since their introduction in the mid 1980's common red lionfish, Pterois volitans, are having dramatic impacts on the Caribbean ecosystem by displacing native species and disrupting food webs. Introduced lionfish capture prey at extraordinary rates, altering the composition of benthic communities. Here we demonstrate that the extraordinary success of the introduced lionfish lies in its capacity to circumvent prey risk assessment abilities as it is virtually undetectable by prey species in its native range. While experienced prey damselfish, Chromis viridis, respond with typical antipredator behaviours when exposed to a common predatory rock cod (Cephalopholis microprion) they fail to visibly react to either the scent or visual presentation of the red lionfish, and responded only to the scent (not the visual cue) of a lionfish of a different genus, Dendrochirus zebra. Experienced prey also had much higher survival when exposed to the two non-invasive predators compared to P. volitans. The cryptic nature of the red lionfish has enabled it to be destructive as a predator and a highly successful invasive species.
ERIC Educational Resources Information Center
Edie, David; Schmid, Deborah
2007-01-01
For decades researchers have been aware of the extraordinary development of a child's brain during the first five years of life. Recent advances in neuroscience have helped crystallize earlier findings, bringing new clarity and understanding to the field of early childhood brain development. Children are born ready to learn. They cultivate 85…
ERIC Educational Resources Information Center
Calkins, Lucy; Ehrenworth, Mary
2016-01-01
Increasingly, school leaders recognize the need for writing instruction to become a schoolwide priority. The writers' workshop approach that was popularized 30 years ago is still relevant; it is still important to give students protected time to write, opportunities to address topics and audiences that matter, and timely feedback. Recent research…
The visual white matter: The application of diffusion MRI and fiber tractography to vision science
Rokem, Ariel; Takemura, Hiromasa; Bock, Andrew S.; Scherf, K. Suzanne; Behrmann, Marlene; Wandell, Brian A.; Fine, Ione; Bridge, Holly; Pestilli, Franco
2017-01-01
Visual neuroscience has traditionally focused much of its attention on understanding the response properties of single neurons or neuronal ensembles. The visual white matter and the long-range neuronal connections it supports are fundamental in establishing such neuronal response properties and visual function. This review article provides an introduction to measurements and methods to study the human visual white matter using diffusion MRI. These methods allow us to measure the microstructural and macrostructural properties of the white matter in living human individuals; they allow us to trace long-range connections between neurons in different parts of the visual system and to measure the biophysical properties of these connections. We also review a range of findings from recent studies on connections between different visual field maps, the effects of visual impairment on the white matter, and the properties underlying networks that process visual information supporting visual face recognition. Finally, we discuss a few promising directions for future studies. These include new methods for analysis of MRI data, open datasets that are becoming available to study brain connectivity and white matter properties, and open source software for the analysis of these data. PMID:28196374
White matter and cognition: making the connection
Fields, R. Douglas
2016-01-01
Whereas the cerebral cortex has long been regarded by neuroscientists as the major locus of cognitive function, the white matter of the brain is increasingly recognized as equally critical for cognition. White matter comprises half of the brain, has expanded more than gray matter in evolution, and forms an indispensable component of distributed neural networks that subserve neurobehavioral operations. White matter tracts mediate the essential connectivity by which human behavior is organized, working in concert with gray matter to enable the extraordinary repertoire of human cognitive capacities. In this review, we present evidence from behavioral neurology that white matter lesions regularly disturb cognition, consider the role of white matter in the physiology of distributed neural networks, develop the hypothesis that white matter dysfunction is relevant to neurodegenerative disorders, including Alzheimer's disease and the newly described entity chronic traumatic encephalopathy, and discuss emerging concepts regarding the prevention and treatment of cognitive dysfunction associated with white matter disorders. Investigation of the role of white matter in cognition has yielded many valuable insights and promises to expand understanding of normal brain structure and function, improve the treatment of many neurobehavioral disorders, and disclose new opportunities for research on many challenging problems facing medicine and society. PMID:27512019
Cognitive Skills Training Improves Listening and Visual Memory for Academic and Career Success.
ERIC Educational Resources Information Center
Erland, Jan
The Mem-ExSpan Accelerative Cognitive Training System (MESACTS) is described as a cognitive skills training program for schools, businesses, and industry. The program achieves extraordinary academic results in reading and mathematics with 1 semester of input 4 days a week for 30 minutes a day. Intensive versions of the program accelerate…
NASA Technical Reports Server (NTRS)
Christensen, Andrew B.; Spann, James; Cyr, O. C.; Cummings, Alan; Heelis, Roderick; Hill, Frank; Immel, Thomas; Kasper, Justin; Kistler, Lynn; Kuhn, Jeffrey;
2009-01-01
Our planet is immersed in a seemingly invisible yet exotic and inherently dangerous environment. Above the protective cocoon of Earth's lower atmosphere is a plasma soup composed of electrified and magnetized matter entwined with penetrating radiation and energetic particles. The Earth's magnetic field interacts with the Sun's outer atmosphere to create this extraordinary environment.
Trombiculiasis: not only a matter of animals!
Guarneri, Claudio; Chokoeva, Anastasiya Atanasova; Wollina, Uwe; Lotti, Torello; Tchernev, Georgi
2017-03-01
Trombiculiasis represents a striking emerging infestation in humans. In fact, modified lifestyles and easy and quick traveling around the globe, together with the altered ecology and habits of the parasite Neotrombicula autumnalis, make this original epizoonosis an extraordinary example of synanthropic dermatosis. We present an additional clinical image of this unusual parasite transmission from animals to humans occurring in a trekker in Calabria, Italy.
Gignac, Paul M; Kley, Nathan J
2014-05-01
The now widespread use of non-destructive X-ray computed tomography (CT) and micro-CT (µCT) has greatly augmented our ability to comprehensively detail and quantify the internal hard-tissue anatomy of vertebrates. However, the utility of X-ray imaging for gaining similar insights into vertebrate soft-tissue anatomy has yet to be fully realized due to the naturally low X-ray absorption of non-mineralized tissues. In this study, we show how a wide diversity of soft-tissue structures within the vertebrate head-including muscles, glands, fat deposits, perichondria, dural venous sinuses, white and gray matter of the brain, as well as cranial nerves and associated ganglia-can be rapidly visualized in their natural relationships with extraordinary levels of detail using iodine-enhanced (i-e) µCT imaging. To date, Lugol's iodine solution (I2 KI) has been used as a contrast agent for µCT imaging of small invertebrates, vertebrate embryos, and certain isolated parts of larger, post-embryonic vertebrates. These previous studies have all yielded promising results, but visualization of soft tissues in smaller invertebrate and embryonic vertebrate specimens has generally been more complete than that for larger, post-embryonic vertebrates. Our research builds on these previous studies by using high-energy µCT together with more highly concentrated I2 KI solutions and longer staining times to optimize the imaging and differentiation of soft tissues within the heads of post-embryonic archosaurs (Alligator mississippiensis and Dromaius novaehollandiae). We systematically quantify the intensities of tissue staining, demonstrate the range of anatomical structures that can be visualized, and generate a partial three-dimensional reconstruction of alligator cephalic soft-tissue anatomy. © 2014 Wiley Periodicals, Inc.
Altered white matter in early visual pathways of humans with amblyopia.
Allen, Brian; Spiegel, Daniel P; Thompson, Benjamin; Pestilli, Franco; Rokers, Bas
2015-09-01
Amblyopia is a visual disorder caused by poorly coordinated binocular input during development. Little is known about the impact of amblyopia on the white matter within the visual system. We studied the properties of six major visual white-matter pathways in a group of adults with amblyopia (n=10) and matched controls (n=10) using diffusion weighted imaging (DWI) and fiber tractography. While we did not find significant differences in diffusion properties in cortico-cortical pathways, patients with amblyopia exhibited increased mean diffusivity in thalamo-cortical visual pathways. These findings suggest that amblyopia may systematically alter the white matter properties of early visual pathways. Copyright © 2015 Elsevier Ltd. All rights reserved.
NASA Astrophysics Data System (ADS)
Buck, Z.
2013-04-01
As we turn more and more to high-end computing to understand the Universe at cosmological scales, visualizations of simulations will take on a vital role as perceptual and cognitive tools. In collaboration with the Adler Planetarium and University of California High-Performance AstroComputing Center (UC-HiPACC), I am interested in better understanding the use of visualizations to mediate astronomy learning across formal and informal settings. The aspect of my research that I present here uses quantitative methods to investigate how learners are relying on color to interpret dark matter in a cosmology visualization. The concept of dark matter is vital to our current understanding of the Universe, and yet we do not know how to effectively present dark matter visually to support learning. I employ an alternative treatment post-test only experimental design, in which members of an equivalent sample are randomly assigned to one of three treatment groups, followed by treatment and a post-test. Results indicate significant correlation (p < .05) between the color of dark matter in the visualization and survey responses, implying that aesthetic variations like color can have a profound effect on audience interpretation of a cosmology visualization.
Extraordinary diversity of visual opsin genes in dragonflies
Futahashi, Ryo; Kawahara-Miki, Ryouka; Kinoshita, Michiyo; Yoshitake, Kazutoshi; Yajima, Shunsuke; Arikawa, Kentaro; Fukatsu, Takema
2015-01-01
Dragonflies are colorful and large-eyed animals strongly dependent on color vision. Here we report an extraordinary large number of opsin genes in dragonflies and their characteristic spatiotemporal expression patterns. Exhaustive transcriptomic and genomic surveys of three dragonflies of the family Libellulidae consistently identified 20 opsin genes, consisting of 4 nonvisual opsin genes and 16 visual opsin genes of 1 UV, 5 short-wavelength (SW), and 10 long-wavelength (LW) type. Comprehensive transcriptomic survey of the other dragonflies representing an additional 10 families also identified as many as 15–33 opsin genes. Molecular phylogenetic analysis revealed dynamic multiplications and losses of the opsin genes in the course of evolution. In contrast to many SW and LW genes expressed in adults, only one SW gene and several LW genes were expressed in larvae, reflecting less visual dependence and LW-skewed light conditions for their lifestyle under water. In this context, notably, the sand-burrowing or pit-dwelling species tended to lack SW gene expression in larvae. In adult visual organs: (i) many SW genes and a few LW genes were expressed in the dorsal region of compound eyes, presumably for processing SW-skewed light from the sky; (ii) a few SW genes and many LW genes were expressed in the ventral region of compound eyes, probably for perceiving terrestrial objects; and (iii) expression of a specific LW gene was associated with ocelli. Our findings suggest that the stage- and region-specific expressions of the diverse opsin genes underlie the behavior, ecology, and adaptation of dragonflies. PMID:25713365
Visual White Matter Integrity in Schizophrenia
Butler, Pamela D.; Hoptman, Matthew J.; Nierenberg, Jay; Foxe, John J.; Javitt, Daniel C.; Lim, Kelvin O.
2007-01-01
Objective Patients with schizophrenia have visual-processing deficits. This study examines visual white matter integrity as a potential mechanism for these deficits. Method Diffusion tensor imaging was used to examine white matter integrity at four levels of the visual system in 17 patients with schizophrenia and 21 comparison subjects. The levels examined were the optic radiations, the striate cortex, the inferior parietal lobule, and the fusiform gyrus. Results Schizophrenia patients showed a significant decrease in fractional anisotropy in the optic radiations but not in any other region. Conclusions This finding indicates that white matter integrity is more impaired at initial input, rather than at higher levels of the visual system, and supports the hypothesis that visual-processing deficits occur at the early stages of processing. PMID:17074957
Ultimate Predators: Lionfish Have Evolved to Circumvent Prey Risk Assessment Abilities
Lönnstedt, Oona M.; McCormick, Mark I.
2013-01-01
Invasive species cause catastrophic alterations to communities worldwide by changing the trophic balance within ecosystems. Ever since their introduction in the mid 1980's common red lionfish, Pterois volitans, are having dramatic impacts on the Caribbean ecosystem by displacing native species and disrupting food webs. Introduced lionfish capture prey at extraordinary rates, altering the composition of benthic communities. Here we demonstrate that the extraordinary success of the introduced lionfish lies in its capacity to circumvent prey risk assessment abilities as it is virtually undetectable by prey species in its native range. While experienced prey damselfish, Chromis viridis, respond with typical antipredator behaviours when exposed to a common predatory rock cod (Cephalopholis microprion) they fail to visibly react to either the scent or visual presentation of the red lionfish, and responded only to the scent (not the visual cue) of a lionfish of a different genus, Dendrochirus zebra. Experienced prey also had much higher survival when exposed to the two non-invasive predators compared to P. volitans. The cryptic nature of the red lionfish has enabled it to be destructive as a predator and a highly successful invasive species. PMID:24146775
NASA Astrophysics Data System (ADS)
Fernández, E.; Pelayo, F.; Romero, S.; Bongard, M.; Marin, C.; Alfaro, A.; Merabet, L.
2005-12-01
Clinical applications such as artificial vision require extraordinary, diverse, lengthy and intimate collaborations among basic scientists, engineers and clinicians. In this review, we present the state of research on a visual neuroprosthesis designed to interface with the occipital visual cortex as a means through which a limited, but useful, visual sense could be restored in profoundly blind individuals. We review the most important physiological principles regarding this neuroprosthetic approach and emphasize the role of neural plasticity in order to achieve desired behavioral outcomes. While full restoration of fine detailed vision with current technology is unlikely in the immediate near future, the discrimination of shapes and the localization of objects should be possible allowing blind subjects to navigate in a unfamiliar environment and perhaps even to read enlarged text. Continued research and development in neuroprosthesis technology will likely result in a substantial improvement in the quality of life of blind and visually impaired individuals.
Egelhaaf, Martin; Kern, Roland
2002-12-01
Vision guides flight behaviour in numerous insects. Despite their small brain, insects easily outperform current man-made autonomous vehicles in many respects. Examples are the virtuosic chasing manoeuvres male flies perform as part of their mating behaviour and the ability of bees to assess, on the basis of visual motion cues, the distance travelled in a novel environment. Analyses at both the behavioural and neuronal levels are beginning to unveil reasons for such extraordinary capabilities of insects. One recipe for their success is the adaptation of visual information processing to the specific requirements of the behavioural tasks and to the specific spatiotemporal properties of the natural input.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Stone, Maureen; Kasik, David; Bailey, Mike
Jim Thomas, a visionary scientist and inspirational leader, died on 6 August 2010 in Richland, Washington. His impact on the fields of computer graphics, user interface software, and visualization was extraordinary, his ability to personally change people’s lives even more so. He is remembered for his enthusiasm, his mentorship, his generosity, and, most of all, his laughter. This collection of remembrances images him through the eyes of his many friends.
Mundinano, Inaki-Carril; Chen, Juan; de Souza, Mitchell; Sarossy, Marc G; Joanisse, Marc F; Goodale, Melvyn A; Bourne, James A
2017-11-13
Injury to the primary visual cortex (V1, striate cortex) and the geniculostriate pathway in adults results in cortical blindness, abolishing conscious visual perception. Early studies by Larry Weiskrantz and colleagues demonstrated that some patients with an occipital-lobe injury exhibited a degree of unconscious vision and visually-guided behaviour within the blind field. A more recent focus has been the observed phenomenon whereby early-life injury to V1 often results in the preservation of visual perception in both monkeys and humans. These findings initiated a concerted effort on multiple fronts, including nonhuman primate studies, to uncover the neural substrate/s of the spared conscious vision. In both adult and early-life cases of V1 injury, evidence suggests the involvement of the Middle Temporal area (MT) of the extrastriate visual cortex, which is an integral component area of the dorsal stream and is also associated with visually-guided behaviors. Because of the limited number of early-life V1 injury cases for humans, the outstanding question in the field is what secondary visual pathways are responsible for this extraordinary capacity? Here we report for the first time a case of a child (B.I.) who suffered a bilateral occipital-lobe injury in the first two weeks postnatally due to medium-chain acyl-Co-A dehydrogenase deficiency. At 6 years of age, B.I. underwent a battery of neurophysiological tests, as well as structural and diffusion MRI and ophthalmic examination at 7 years. Despite the extensive bilateral occipital cortical damage, B.I. has extensive conscious visual abilities, is not blind, and can use vision to navigate his environment. Furthermore, unlike blindsight patients, he can readily and consciously identify happy and neutral faces and colors, tasks associated with ventral stream processing. These findings suggest significant re-routing of visual information. To identify the putative visual pathway/s responsible for this ability, MRI tractography of secondary visual pathways connecting MT with the lateral geniculate nucleus (LGN) and the inferior pulvinar (PI) were analysed. Results revealed an increased PI-MT pathway in the left hemisphere, suggesting that this pulvinar relay could be the neural pathway affording the preserved visual capacity following an early-life lesion of V1. These findings corroborate anatomical evidence from monkeys showing an enhanced PI-MT pathway following an early-life lesion of V1, compared to adults. Copyright © 2017 Elsevier Ltd. All rights reserved.
Interactive Exploration of Cosmological Dark-Matter Simulation Data.
Scherzinger, Aaron; Brix, Tobias; Drees, Dominik; Volker, Andreas; Radkov, Kiril; Santalidis, Niko; Fieguth, Alexander; Hinrichs, Klaus H
2017-01-01
The winning entry of the 2015 IEEE Scientific Visualization Contest, this article describes a visualization tool for cosmological data resulting from dark-matter simulations. The proposed system helps users explore all aspects of the data at once and receive more detailed information about structures of interest at any time. Moreover, novel methods for visualizing and interactively exploring dark-matter halo substructures are proposed.
Buttarazzi, Davide; Pandolfo, Giuseppe; Porzio, Giovanni C
2018-05-21
The box-and-whiskers plot is an extraordinary graphical tool that provides a quick visual summary of an observed distribution. In spite of its many extensions, a really suitable boxplot to display circular data is not yet available. Thanks to its simplicity and strong visual impact, such a tool would be especially useful in all fields where circular measures arise: biometrics, astronomy, environmetrics, Earth sciences, to cite just a few. For this reason, in line with Tukey's original idea, a Tukey-like circular boxplot is introduced. Several simulated and real datasets arising in biology are used to illustrate the proposed graphical tool. © 2018, The International Biometric Society.
ERIC Educational Resources Information Center
Roberts, Siân
2013-01-01
In the late 1930s the Spanish Civil War captured the international imagination to an extraordinary degree. As in other countries British men and women were moved to intervene directly and the memory of the war, and of British participation in it, has held an enduring appeal in the UK. The Civil War was also notable for its use of the visual as a…
Stable Isotopic Composition of Particulate Organic Carbon in the Caspian Sea
NASA Astrophysics Data System (ADS)
Kravchishina, M. D.; Klyuvitkin, A. A.; Pautova, L. A.; Politova, N. V.; Lein, A. Yu.
2018-01-01
The data on the isotopic composition of particulate organic carbon (δ13CPOC) in the Caspian Sea water in summer-autumn 2008, 2010, 2012, and 2013 are discussed in the paper. These data allowed as to reveal the predominant genesis of organic carbon in suspended particulate matter of the active seawater layer (from 0 to 40 m). The δ13CPOC =-27‰ (PDB) and δ13CPOC =-20.5‰ (PDB) values were taken as the reference data for terrigenous and planktonogenic organic matter, respectively. Seasonal (early summer, late summer, and autumn) variations in the composition of suspended particulate matter in the active sea layer were revealed. A shift of δ13CPOC towards greater values was seen in autumn (with a slight outburst in the development (bloom) of phytoplankton) in comparison with summer (with large accumulations and an extraordinary phytoplankton bloom confined to the thermocline area). The seasonal dynamics of autochthonous and allochthonous components in the suspended particulate matter of the Middle and Southern Caspian Sea was studied with the use of data on the concentration of particulate matter and chlorophyll a, the phytoplankton biomass and the POC content.
"Dark matter" worlds of unstable RNA and protein.
Baboo, Sabyasachi; Cook, Peter R
2014-01-01
Astrophysicists use the term "dark matter" to describe the majority of the matter and/or energy in the universe that is hidden from view, and biologists now apply it to the new families of RNA they are uncovering. We review evidence for an analogous hidden world containing peptides. The critical experiments involved pulse-labeling human cells with tagged amino acids for periods as short as five seconds. Results are extraordinary in two respects: both nucleus and cytoplasm become labeled, and most signals disappear with a half-life of less than one minute. Just as the synthesis of each mature mRNA is regulated by the abortive production of hundreds of shorter transcripts that are quickly degraded, it seems that the synthesis of each full-length protein in the stable proteome is regulated by an apparently wasteful production and degradation of shorter peptides. Some of the nuclear synthesis is probably a byproduct of nuclear ribosomes proofreading newly-made RNA for inappropriately-placed termination codons (a process that triggers "nonsense-mediated decay"). We speculate that some "dark-matter" peptides will play other important roles in the cell.
The Arithmetic of events and a new theory of Gravitation
NASA Astrophysics Data System (ADS)
Abbasi, Malek
2012-04-01
Of fundamental importance in physics is the concept of event. This study tries; first, to provide a mathematical background showing how must deal with these events and based on what laws the watches, another important concept used frequently in this research, record them. Armed, then, with this mathematical background, the Gravitational Clouds Theory, a novel theory of gravitation concerning the role of the matter and energy in the universe, is proposed. This completely new theory leads to miscellanies results some of which are: the second Einstein's postulate; the well known identity E = mc2; the time-dilation phenomenon and Fitzgerald-Lorentz contraction. This theory will also explain why indeed we never feel the speed of the Earth, what is the origin of Dark matter-energy and many other extraordinary results associated with cosmology.
The Arithmetic of Events and a New Theory of Gravitation
NASA Astrophysics Data System (ADS)
Abbasi, Malek
2012-10-01
Of fundamental importance in physics is the concept of event. This study tries, first, to provide a mathematical background showing how must deal with these events and based on what laws the watches, another important concept used frequently in this research, record them. Armed, then, with this mathematical background, the Gravitational Clouds Theory, a novel theory of gravitation concerning the role of the matter and energy in the universe, is proposed. This completely new theory leads to miscellanies results some of which are: the second Einstein's postulate; the well known identity E = mc2; the time-dilation phenomenon and Fitzgerald-Lorentz contraction. This theory will also explain why indeed we never feel the speed of the Earth, what is the origin of Dark matter-energy and many other extraordinary results associated with cosmology.
Bagga, Deepika; Sharma, Aakansha; Kumari, Archana; Kaur, Prabhjot; Bhattacharya, Debajyoti; Garg, Mohan Lal; Khushu, Subash; Singh, Namita
2014-02-01
Chronic alcohol abuse is characterized by impaired cognitive abilities with a more severe deficit in visual than in verbal functions. Neuropathologically, it is associated with widespread brain structural compromise marked by gray matter shrinkage, ventricular enlargement, and white matter degradation. The present study sought to increase current understanding of the impairment of visual processing abilities in alcohol-dependent subjects, and its correlation with white matter microstructural alterations, using diffusion tensor imaging (DTI). To that end, a DTI study was carried out on 35 alcohol-dependent subjects and 30 healthy male control subjects. Neuropsychological tests were assessed for visual processing skills and deficits were reported as raw dysfunction scores (rDyS). Reduced FA (fractional anisotropy) and increased MD (mean diffusivity) were observed bilaterally in inferior and superior fronto-occipital fasciculus (FOF) fiber bundles. A significant inverse correlation in rDyS and FA values was observed in these fiber tracts whereas a positive correlation of these scores was found with the MD values. Our results suggest that FOF fiber bundles linking the frontal lobe to occipital lobe might be related to visual processing skills. This is the first report of an alteration of the white matter microstructure of FOF fiber bundles that might have functional consequences for visual processing in alcohol-dependent subjects who exhibit no neurological complications. Copyright © 2014 Elsevier Inc. All rights reserved.
Audio-visual integration through the parallel visual pathways.
Kaposvári, Péter; Csete, Gergő; Bognár, Anna; Csibri, Péter; Tóth, Eszter; Szabó, Nikoletta; Vécsei, László; Sáry, Gyula; Tamás Kincses, Zsigmond
2015-10-22
Audio-visual integration has been shown to be present in a wide range of different conditions, some of which are processed through the dorsal, and others through the ventral visual pathway. Whereas neuroimaging studies have revealed integration-related activity in the brain, there has been no imaging study of the possible role of segregated visual streams in audio-visual integration. We set out to determine how the different visual pathways participate in this communication. We investigated how audio-visual integration can be supported through the dorsal and ventral visual pathways during the double flash illusion. Low-contrast and chromatic isoluminant stimuli were used to drive preferably the dorsal and ventral pathways, respectively. In order to identify the anatomical substrates of the audio-visual interaction in the two conditions, the psychophysical results were correlated with the white matter integrity as measured by diffusion tensor imaging.The psychophysiological data revealed a robust double flash illusion in both conditions. A correlation between the psychophysical results and local fractional anisotropy was found in the occipito-parietal white matter in the low-contrast condition, while a similar correlation was found in the infero-temporal white matter in the chromatic isoluminant condition. Our results indicate that both of the parallel visual pathways may play a role in the audio-visual interaction. Copyright © 2015. Published by Elsevier B.V.
Nested plasmonic resonances: extraordinary enhancement of linear and nonlinear interactions.
de Ceglia, Domenico; Vincenti, Maria Antonietta; Akozbek, Neset; Bloemer, Mark J; Scalora, Michael
2017-02-20
Plasmonic resonators can provide large local electric fields when the gap between metal components is filled with an ordinary dielectric. We consider a new concept consisting of a hybrid nanoantenna obtained by introducing a resonant, plasmonic nanoparticle strategically placed inside the gap of an aptly sized metallic antenna. The system exhibits two nested, nearly overlapping plasmonic resonances whose signature is a large field enhancement at the surface and within the bulk of the plasmonic nanoparticle that leads to unusually strong, linear and nonlinear light-matter coupling.
Mapping white-matter functional organization at rest and during naturalistic visual perception.
Marussich, Lauren; Lu, Kun-Han; Wen, Haiguang; Liu, Zhongming
2017-02-01
Despite the wide applications of functional magnetic resonance imaging (fMRI) to mapping brain activation and connectivity in cortical gray matter, it has rarely been utilized to study white-matter functions. In this study, we investigated the spatiotemporal characteristics of fMRI data within the white matter acquired from humans both in the resting state and while watching a naturalistic movie. By using independent component analysis and hierarchical clustering, resting-state fMRI data in the white matter were de-noised and decomposed into spatially independent components, which were further assembled into hierarchically organized axonal fiber bundles. Interestingly, such components were partly reorganized during natural vision. Relative to resting state, the visual task specifically induced a stronger degree of temporal coherence within the optic radiations, as well as significant correlations between the optic radiations and multiple cortical visual networks. Therefore, fMRI contains rich functional information about the activity and connectivity within white matter at rest and during tasks, challenging the conventional practice of taking white-matter signals as noise or artifacts. Copyright © 2016 Elsevier Inc. All rights reserved.
Gomez, Jesse; Pestilli, Franco; Witthoft, Nathan; Golarai, Golijeh; Liberman, Alina; Poltoratski, Sonia; Yoon, Jennifer; Grill-Spector, Kalanit
2014-01-01
Summary It is unknown if the white matter properties associated with specific visual networks selectively affect category-specific processing. In a novel protocol we combined measurements of white matter structure, functional selectivity, and behavior in the same subjects. We find two parallel white matter pathways along the ventral temporal lobe connecting to either face-selective or place-selective regions. Diffusion properties of portions of these tracts adjacent to face- and place-selective regions of ventral temporal cortex correlate with behavioral performance for face or place processing, respectively. Strikingly, adults with developmental prosopagnosia (face blindness) express an atypical structure-behavior relationship near face-selective cortex, suggesting that white matter atypicalities in this region may have behavioral consequences. These data suggest that examining the interplay between cortical function, anatomical connectivity, and visual behavior is integral to understanding functional networks and their role in producing visual abilities and deficits. PMID:25569351
Is extraordinary prosocial behavior more valuable than ordinary prosocial behavior?
2018-01-01
This study examined how people evaluate ordinary and extraordinary prosocial behaviors, especially their predictions of the likelihood of future prosocial behaviors of ordinary and extraordinary prosocial actors (Study 1). Further, it examined the individual effects of ordinary and extraordinary prosocial behaviors of an actor on the evaluation of his/her trait by considering the cases where the actor engages in and does not engage in the other behavior (Study 2). Study 1 revealed that the likelihood of future prosocial behaviors of ordinary and extraordinary prosocial actors was perceived asymmetrically. Specifically, while the likelihood of ordinary prosocial actors to engage in ordinary prosocial behaviors was perceived as high, the same perception was not observed for extraordinary prosocial behaviors. On the other hand, extraordinary prosocial actors were perceived as highly likely to engage in both ordinary and extraordinary prosocial behaviors. Study 2 revealed that the evaluation of actors who engaged in extraordinary prosocial behaviors but not ordinary prosocial behaviors did not exceed the evaluation of actors who engaged in ordinary prosocial behaviors but not extraordinary prosocial behaviors. Additionally, the effect of extraordinary prosocial behaviors was more when the actor also engaged in ordinary prosocial behaviors. These results suggest that extraordinary prosocial actors are evaluated highly when they also engage in ordinary prosocial behaviors. PMID:29684088
Is extraordinary prosocial behavior more valuable than ordinary prosocial behavior?
Futamura, Ikumi
2018-01-01
This study examined how people evaluate ordinary and extraordinary prosocial behaviors, especially their predictions of the likelihood of future prosocial behaviors of ordinary and extraordinary prosocial actors (Study 1). Further, it examined the individual effects of ordinary and extraordinary prosocial behaviors of an actor on the evaluation of his/her trait by considering the cases where the actor engages in and does not engage in the other behavior (Study 2). Study 1 revealed that the likelihood of future prosocial behaviors of ordinary and extraordinary prosocial actors was perceived asymmetrically. Specifically, while the likelihood of ordinary prosocial actors to engage in ordinary prosocial behaviors was perceived as high, the same perception was not observed for extraordinary prosocial behaviors. On the other hand, extraordinary prosocial actors were perceived as highly likely to engage in both ordinary and extraordinary prosocial behaviors. Study 2 revealed that the evaluation of actors who engaged in extraordinary prosocial behaviors but not ordinary prosocial behaviors did not exceed the evaluation of actors who engaged in ordinary prosocial behaviors but not extraordinary prosocial behaviors. Additionally, the effect of extraordinary prosocial behaviors was more when the actor also engaged in ordinary prosocial behaviors. These results suggest that extraordinary prosocial actors are evaluated highly when they also engage in ordinary prosocial behaviors.
Valley Vortex States in Sonic Crystals
NASA Astrophysics Data System (ADS)
Lu, Jiuyang; Qiu, Chunyin; Ke, Manzhu; Liu, Zhengyou
2016-03-01
Valleytronics is quickly emerging as an exciting field in fundamental and applied research. In this Letter, we study the acoustic version of valley states in sonic crystals and reveal a vortex nature of such states. In addition to the selection rules established for exciting valley polarized states, a mimicked valley Hall effect of sound is proposed further. The extraordinary chirality of valley vortex states, detectable in experiments, may open a new possibility in sound manipulations. This is appealing to scalar acoustics that lacks a spin degree of freedom inherently. In addition, the valley selection enables a handy way to create vortex matter in acoustics, in which the vortex chirality can be controlled flexibly. Potential applications can be anticipated with the exotic interaction of acoustic vortices with matter, such as to trigger the rotation of the trapped microparticles without contact.
Visual System Involvement in Patients with Newly Diagnosed Parkinson Disease.
Arrigo, Alessandro; Calamuneri, Alessandro; Milardi, Demetrio; Mormina, Enricomaria; Rania, Laura; Postorino, Elisa; Marino, Silvia; Di Lorenzo, Giuseppe; Anastasi, Giuseppe Pio; Ghilardi, Maria Felice; Aragona, Pasquale; Quartarone, Angelo; Gaeta, Michele
2017-12-01
Purpose To assess intracranial visual system changes of newly diagnosed Parkinson disease in drug-naïve patients. Materials and Methods Twenty patients with newly diagnosed Parkinson disease and 20 age-matched control subjects were recruited. Magnetic resonance (MR) imaging (T1-weighted and diffusion-weighted imaging) was performed with a 3-T MR imager. White matter changes were assessed by exploring a white matter diffusion profile by means of diffusion-tensor imaging-based parameters and constrained spherical deconvolution-based connectivity analysis and by means of white matter voxel-based morphometry (VBM). Alterations in occipital gray matter were investigated by means of gray matter VBM. Morphologic analysis of the optic chiasm was based on manual measurement of regions of interest. Statistical testing included analysis of variance, t tests, and permutation tests. Results In the patients with Parkinson disease, significant alterations were found in optic radiation connectivity distribution, with decreased lateral geniculate nucleus V2 density (F, -8.28; P < .05), a significant increase in optic radiation mean diffusivity (F, 7.5; P = .014), and a significant reduction in white matter concentration. VBM analysis also showed a significant reduction in visual cortical volumes (P < .05). Moreover, the chiasmatic area and volume were significantly reduced (P < .05). Conclusion The findings show that visual system alterations can be detected in early stages of Parkinson disease and that the entire intracranial visual system can be involved. © RSNA, 2017 Online supplemental material is available for this article.
2017-01-01
Nocturnal insects have evolved remarkable visual capacities, despite small eyes and tiny brains. They can see colour, control flight and land, react to faint movements in their environment, navigate using dim celestial cues and find their way home after a long and tortuous foraging trip using learned visual landmarks. These impressive visual abilities occur at light levels when only a trickle of photons are being absorbed by each photoreceptor, begging the question of how the visual system nonetheless generates the reliable signals needed to steer behaviour. In this review, I attempt to provide an answer to this question. Part of the answer lies in their compound eyes, which maximize light capture. Part lies in the slow responses and high gains of their photoreceptors, which improve the reliability of visual signals. And a very large part lies in the spatial and temporal summation of these signals in the optic lobe, a strategy that substantially enhances contrast sensitivity in dim light and allows nocturnal insects to see a brighter world, albeit a slower and coarser one. What is abundantly clear, however, is that during their evolution insects have overcome several serious potential visual limitations, endowing them with truly extraordinary night vision. This article is part of the themed issue ‘Vision in dim light’. PMID:28193808
Thinner retinal layers are associated with changes in the visual pathway: A population-based study.
Mutlu, Unal; Ikram, Mohammad K; Roshchupkin, Gennady V; Bonnemaijer, Pieter W M; Colijn, Johanna M; Vingerling, Johannes R; Niessen, Wiro J; Ikram, Mohammad A; Klaver, Caroline C W; Vernooij, Meike W
2018-06-23
Increasing evidence shows that thinner retinal nerve fiber layer (RNFL) and ganglion cell layer (GCL), assessed on optical coherence tomography (OCT), are reflecting global brain atrophy. Yet, little is known on the relation of these layers with specific brain regions. Using voxel-based analysis, we aimed to unravel specific brain regions associated with these retinal layers. We included 2,235 persons (mean age: 67.3 years, 55% women) from the Rotterdam Study (2007-2012) who had gradable retinal OCT images and brain magnetic resonance imaging (MRI) scans, including diffusion tensor (DT) imaging. Thicknesses of peripapillary RNFL and perimacular GCL were measured using an automated segmentation algorithm. Voxel-based morphometry protocols were applied to process DT-MRI data. We investigated the association between retinal layer thickness with voxel-wise gray matter density and white matter microstructure by performing linear regression models. We found that thinner RNFL and GCL were associated with lower gray matter density in the visual cortex, and with lower fractional anisotropy and higher mean diffusivity in white matter tracts that are part of the optic radiation. Furthermore, thinner GCL was associated with lower gray matter density of the thalamus. Thinner RNFL and GCL are associated with gray and white matter changes in the visual pathway suggesting that retinal thinning on OCT may be specifically associated with changes in the visual pathway rather than with changes in the global brain. These findings may serve as a basis for understanding visual symptoms in elderly patients, patients with Alzheimer's disease, or patients with posterior cortical atrophy. © 2018 Wiley Periodicals, Inc.
The Conceptual Grouping Effect: Categories Matter (and Named Categories Matter More)
ERIC Educational Resources Information Center
Lupyan, Gary
2008-01-01
Do conceptual categories affect basic visual processing? A conceptual grouping effect for familiar stimuli is reported using a visual search paradigm. Search through conceptually-homogeneous non-targets was faster and more efficient than search through conceptually-heterogeneous non-targets. This effect cannot be attributed to perceptual factors…
Neuronal integration in visual cortex elevates face category tuning to conscious face perception
Fahrenfort, Johannes J.; Snijders, Tineke M.; Heinen, Klaartje; van Gaal, Simon; Scholte, H. Steven; Lamme, Victor A. F.
2012-01-01
The human brain has the extraordinary capability to transform cluttered sensory input into distinct object representations. For example, it is able to rapidly and seemingly without effort detect object categories in complex natural scenes. Surprisingly, category tuning is not sufficient to achieve conscious recognition of objects. What neural process beyond category extraction might elevate neural representations to the level where objects are consciously perceived? Here we show that visible and invisible faces produce similar category-selective responses in the ventral visual cortex. The pattern of neural activity evoked by visible faces could be used to decode the presence of invisible faces and vice versa. However, only visible faces caused extensive response enhancements and changes in neural oscillatory synchronization, as well as increased functional connectivity between higher and lower visual areas. We conclude that conscious face perception is more tightly linked to neural processes of sustained information integration and binding than to processes accommodating face category tuning. PMID:23236162
White matter tract integrity predicts visual search performance in young and older adults.
Bennett, Ilana J; Motes, Michael A; Rao, Neena K; Rypma, Bart
2012-02-01
Functional imaging research has identified frontoparietal attention networks involved in visual search, with mixed evidence regarding whether different networks are engaged when the search target differs from distracters by a single (elementary) versus multiple (conjunction) features. Neural correlates of visual search, and their potential dissociation, were examined here using integrity of white matter connecting the frontoparietal networks. The effect of aging on these brain-behavior relationships was also of interest. Younger and older adults performed a visual search task and underwent diffusion tensor imaging (DTI) to reconstruct 2 frontoparietal (superior and inferior longitudinal fasciculus; SLF and ILF) and 2 midline (genu, splenium) white matter tracts. As expected, results revealed age-related declines in conjunction, but not elementary, search performance; and in ILF and genu tract integrity. Importantly, integrity of the superior longitudinal fasciculus, ILF, and genu tracts predicted search performance (conjunction and elementary), with no significant age group differences in these relationships. Thus, integrity of white matter tracts connecting frontoparietal attention networks contributes to search performance in younger and older adults. Copyright © 2012 Elsevier Inc. All rights reserved.
White Matter Tract Integrity Predicts Visual Search Performance in Young and Older Adults
Bennett, Ilana J.; Motes, Michael A.; Rao, Neena K.; Rypma, Bart
2011-01-01
Functional imaging research has identified fronto-parietal attention networks involved in visual search, with mixed evidence regarding whether different networks are engaged when the search target differs from distracters by a single (elementary) versus multiple (conjunction) features. Neural correlates of visual search, and their potential dissociation, were examined here using integrity of white matter connecting the fronto-parietal networks. The effect of aging on these brain-behavior relationships was also of interest. Younger and older adults performed a visual search task and underwent diffusion tensor imaging (DTI) to reconstruct two fronto-parietal (superior and inferior longitudinal fasciculus, SLF and ILF) and two midline (genu, splenium) white matter tracts. As expected, results revealed age-related declines in conjunction, but not elementary, search performance; and in ILF and genu tract integrity. Importantly, integrity of the SLF, ILF, and genu tracts predicted search performance (conjunction and elementary), with no significant age group differences in these relationships. Thus, integrity of white matter tracts connecting fronto-parietal attention networks contributes to search performance in younger and older adults. PMID:21402431
10 CFR 140.83 - Determination of extraordinary nuclear occurrence.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 10 Energy 2 2014-01-01 2014-01-01 false Determination of extraordinary nuclear occurrence. 140.83 Section 140.83 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) FINANCIAL PROTECTION REQUIREMENTS AND INDEMNITY AGREEMENTS Extraordinary Nuclear Occurrences § 140.83 Determination of extraordinary nuclear...
10 CFR 140.83 - Determination of extraordinary nuclear occurrence.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 10 Energy 2 2011-01-01 2011-01-01 false Determination of extraordinary nuclear occurrence. 140.83 Section 140.83 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) FINANCIAL PROTECTION REQUIREMENTS AND INDEMNITY AGREEMENTS Extraordinary Nuclear Occurrences § 140.83 Determination of extraordinary nuclear...
10 CFR 140.83 - Determination of extraordinary nuclear occurrence.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 10 Energy 2 2013-01-01 2013-01-01 false Determination of extraordinary nuclear occurrence. 140.83 Section 140.83 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) FINANCIAL PROTECTION REQUIREMENTS AND INDEMNITY AGREEMENTS Extraordinary Nuclear Occurrences § 140.83 Determination of extraordinary nuclear...
10 CFR 140.83 - Determination of extraordinary nuclear occurrence.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 10 Energy 2 2012-01-01 2012-01-01 false Determination of extraordinary nuclear occurrence. 140.83 Section 140.83 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) FINANCIAL PROTECTION REQUIREMENTS AND INDEMNITY AGREEMENTS Extraordinary Nuclear Occurrences § 140.83 Determination of extraordinary nuclear...
10 CFR 140.83 - Determination of extraordinary nuclear occurrence.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 10 Energy 2 2010-01-01 2010-01-01 false Determination of extraordinary nuclear occurrence. 140.83 Section 140.83 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) FINANCIAL PROTECTION REQUIREMENTS AND INDEMNITY AGREEMENTS Extraordinary Nuclear Occurrences § 140.83 Determination of extraordinary nuclear...
Warrant, Eric J
2017-04-05
Nocturnal insects have evolved remarkable visual capacities, despite small eyes and tiny brains. They can see colour, control flight and land, react to faint movements in their environment, navigate using dim celestial cues and find their way home after a long and tortuous foraging trip using learned visual landmarks. These impressive visual abilities occur at light levels when only a trickle of photons are being absorbed by each photoreceptor, begging the question of how the visual system nonetheless generates the reliable signals needed to steer behaviour. In this review, I attempt to provide an answer to this question. Part of the answer lies in their compound eyes, which maximize light capture. Part lies in the slow responses and high gains of their photoreceptors, which improve the reliability of visual signals. And a very large part lies in the spatial and temporal summation of these signals in the optic lobe, a strategy that substantially enhances contrast sensitivity in dim light and allows nocturnal insects to see a brighter world, albeit a slower and coarser one. What is abundantly clear, however, is that during their evolution insects have overcome several serious potential visual limitations, endowing them with truly extraordinary night vision.This article is part of the themed issue 'Vision in dim light'. © 2017 The Author(s).
Bauer, Corinna M.; Heidary, Gena; Koo, Bang-Bon; Killiany, Ronald J.; Bex, Peter; Merabet, Lotfi B.
2014-01-01
Cortical (cerebral) visual impairment (CVI) is characterized by visual dysfunction associated with damage to the optic radiations and/or visual cortex. Typically it results from pre- or perinatal hypoxic damage to postchiasmal visual structures and pathways. The neuroanatomical basis of this condition remains poorly understood, particularly with regard to how the resulting maldevelopment of visual processing pathways relates to observations in the clinical setting. We report our investigation of 2 young adults diagnosed with CVI and visual dysfunction characterized by difficulties related to visually guided attention and visuospatial processing. Using high-angular-resolution diffusion imaging (HARDI), we characterized and compared their individual white matter projections of the extrageniculo-striate visual system with a normal-sighted control. Compared to a sighted control, both CVI cases revealed a striking reduction in association fibers, including the inferior frontal-occipital fasciculus as well as superior and inferior longitudinal fasciculi. This reduction in fibers associated with the major pathways implicated in visual processing may provide a neuroanatomical basis for the visual dysfunctions observed in these patients. PMID:25087644
ERIC Educational Resources Information Center
Espinosa, Allen A.; Marasigan, Arlyne C.; Datukan, Janir T.
2016-01-01
This study explored how students visualise the states and classifications of matter with the use of scientific models. Misconceptions of students in using scientific models were also identified to formulate a teaching framework. To elicit data in the study, a Visual Conception Questionnaire was administered to thirty-four (34), firstyear, general…
10 CFR 840.3 - Determination of extraordinary nuclear occurrence.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 10 Energy 4 2012-01-01 2012-01-01 false Determination of extraordinary nuclear occurrence. 840.3 Section 840.3 Energy DEPARTMENT OF ENERGY EXTRAORDINARY NUCLEAR OCCURRENCES § 840.3 Determination of extraordinary nuclear occurrence. If the DOE determines that both of the criteria set forth in § 840.4 and § 840...
10 CFR 840.3 - Determination of extraordinary nuclear occurrence.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 10 Energy 4 2013-01-01 2013-01-01 false Determination of extraordinary nuclear occurrence. 840.3 Section 840.3 Energy DEPARTMENT OF ENERGY EXTRAORDINARY NUCLEAR OCCURRENCES § 840.3 Determination of extraordinary nuclear occurrence. If the DOE determines that both of the criteria set forth in § 840.4 and § 840...
10 CFR 840.3 - Determination of extraordinary nuclear occurrence.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 10 Energy 4 2014-01-01 2014-01-01 false Determination of extraordinary nuclear occurrence. 840.3 Section 840.3 Energy DEPARTMENT OF ENERGY EXTRAORDINARY NUCLEAR OCCURRENCES § 840.3 Determination of extraordinary nuclear occurrence. If the DOE determines that both of the criteria set forth in § 840.4 and § 840...
10 CFR 840.3 - Determination of extraordinary nuclear occurrence.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 10 Energy 4 2010-01-01 2010-01-01 false Determination of extraordinary nuclear occurrence. 840.3 Section 840.3 Energy DEPARTMENT OF ENERGY EXTRAORDINARY NUCLEAR OCCURRENCES § 840.3 Determination of extraordinary nuclear occurrence. If the DOE determines that both of the criteria set forth in § 840.4 and § 840...
10 CFR 840.3 - Determination of extraordinary nuclear occurrence.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 10 Energy 4 2011-01-01 2011-01-01 false Determination of extraordinary nuclear occurrence. 840.3 Section 840.3 Energy DEPARTMENT OF ENERGY EXTRAORDINARY NUCLEAR OCCURRENCES § 840.3 Determination of extraordinary nuclear occurrence. If the DOE determines that both of the criteria set forth in § 840.4 and § 840...
Canvas and cosmos: Visual art techniques applied to astronomy data
NASA Astrophysics Data System (ADS)
English, Jayanne
Bold color images from telescopes act as extraordinary ambassadors for research astronomers because they pique the public’s curiosity. But are they snapshots documenting physical reality? Or are we looking at artistic spacescapes created by digitally manipulating astronomy images? This paper provides a tour of how original black and white data, from all regimes of the electromagnetic spectrum, are converted into the color images gracing popular magazines, numerous websites, and even clothing. The history and method of the technical construction of these images is outlined. However, the paper focuses on introducing the scientific reader to visual literacy (e.g. human perception) and techniques from art (e.g. composition, color theory) since these techniques can produce not only striking but politically powerful public outreach images. When created by research astronomers, the cultures of science and visual art can be balanced and the image can illuminate scientific results sufficiently strongly that the images are also used in research publications. Included are reflections on how they could feedback into astronomy research endeavors and future forms of visualization as well as on the relevance of outreach images to visual art. (See the color online PDF version at http://dx.doi.org/10.1142/S0218271817300105; the figures can be enlarged in PDF viewers.)
Price, D; Tyler, L K; Neto Henriques, R; Campbell, K L; Williams, N; Treder, M S; Taylor, J R; Henson, R N A
2017-06-09
Slowing is a common feature of ageing, yet a direct relationship between neural slowing and brain atrophy is yet to be established in healthy humans. We combine magnetoencephalographic (MEG) measures of neural processing speed with magnetic resonance imaging (MRI) measures of white and grey matter in a large population-derived cohort to investigate the relationship between age-related structural differences and visual evoked field (VEF) and auditory evoked field (AEF) delay across two different tasks. Here we use a novel technique to show that VEFs exhibit a constant delay, whereas AEFs exhibit delay that accumulates over time. White-matter (WM) microstructure in the optic radiation partially mediates visual delay, suggesting increased transmission time, whereas grey matter (GM) in auditory cortex partially mediates auditory delay, suggesting less efficient local processing. Our results demonstrate that age has dissociable effects on neural processing speed, and that these effects relate to different types of brain atrophy.
Price, D.; Tyler, L. K.; Neto Henriques, R.; Campbell, K. L.; Williams, N.; Treder, M.S.; Taylor, J. R.; Brayne, Carol; Bullmore, Edward T.; Calder, Andrew C.; Cusack, Rhodri; Dalgleish, Tim; Duncan, John; Matthews, Fiona E.; Marslen-Wilson, William D.; Rowe, James B.; Shafto, Meredith A.; Cheung, Teresa; Davis, Simon; Geerligs, Linda; Kievit, Rogier; McCarrey, Anna; Mustafa, Abdur; Samu, David; Tsvetanov, Kamen A.; van Belle, Janna; Bates, Lauren; Emery, Tina; Erzinglioglu, Sharon; Gadie, Andrew; Gerbase, Sofia; Georgieva, Stanimira; Hanley, Claire; Parkin, Beth; Troy, David; Auer, Tibor; Correia, Marta; Gao, Lu; Green, Emma; Allen, Jodie; Amery, Gillian; Amunts, Liana; Barcroft, Anne; Castle, Amanda; Dias, Cheryl; Dowrick, Jonathan; Fair, Melissa; Fisher, Hayley; Goulding, Anna; Grewal, Adarsh; Hale, Geoff; Hilton, Andrew; Johnson, Frances; Johnston, Patricia; Kavanagh-Williamson, Thea; Kwasniewska, Magdalena; McMinn, Alison; Norman, Kim; Penrose, Jessica; Roby, Fiona; Rowland, Diane; Sargeant, John; Squire, Maggie; Stevens, Beth; Stoddart, Aldabra; Stone, Cheryl; Thompson, Tracy; Yazlik, Ozlem; Barnes, Dan; Dixon, Marie; Hillman, Jaya; Mitchell, Joanne; Villis, Laura; Henson, R. N. A.
2017-01-01
Slowing is a common feature of ageing, yet a direct relationship between neural slowing and brain atrophy is yet to be established in healthy humans. We combine magnetoencephalographic (MEG) measures of neural processing speed with magnetic resonance imaging (MRI) measures of white and grey matter in a large population-derived cohort to investigate the relationship between age-related structural differences and visual evoked field (VEF) and auditory evoked field (AEF) delay across two different tasks. Here we use a novel technique to show that VEFs exhibit a constant delay, whereas AEFs exhibit delay that accumulates over time. White-matter (WM) microstructure in the optic radiation partially mediates visual delay, suggesting increased transmission time, whereas grey matter (GM) in auditory cortex partially mediates auditory delay, suggesting less efficient local processing. Our results demonstrate that age has dissociable effects on neural processing speed, and that these effects relate to different types of brain atrophy. PMID:28598417
Early visual cortical structural changes in diabetic patients without diabetic retinopathy.
Ferreira, Fábio S; Pereira, João M S; Reis, Aldina; Sanches, Mafalda; Duarte, João V; Gomes, Leonor; Moreno, Carolina; Castelo-Branco, Miguel
2017-11-01
It is known that diabetic patients have changes in cortical morphometry as compared to controls, but it remains to be clarified whether the visual cortex is a disease target, even when diabetes complications such as retinopathy are absent. Therefore, we compared type 2 diabetes patients without diabetic retinopathy with control subjects using magnetic resonance imaging to assess visual cortical changes when retinal damage is not yet present. We performed T1-weighted imaging in 24 type 2 diabetes patients without diabetic retinopathy and 27 age- and gender-matched controls to compare gray matter changes in the occipital cortex between groups using voxel based morphometry. Patients without diabetic retinopathy showed reduced gray matter volume in the occipital lobe when compared with controls. Reduced gray matter volume in the occipital cortex was found in diabetic patients without retinal damage. We conclude that cortical early visual processing regions may be affected in diabetic patients even before retinal damage occurs.
Learning a generative model of images by factoring appearance and shape.
Le Roux, Nicolas; Heess, Nicolas; Shotton, Jamie; Winn, John
2011-03-01
Computer vision has grown tremendously in the past two decades. Despite all efforts, existing attempts at matching parts of the human visual system's extraordinary ability to understand visual scenes lack either scope or power. By combining the advantages of general low-level generative models and powerful layer-based and hierarchical models, this work aims at being a first step toward richer, more flexible models of images. After comparing various types of restricted Boltzmann machines (RBMs) able to model continuous-valued data, we introduce our basic model, the masked RBM, which explicitly models occlusion boundaries in image patches by factoring the appearance of any patch region from its shape. We then propose a generative model of larger images using a field of such RBMs. Finally, we discuss how masked RBMs could be stacked to form a deep model able to generate more complicated structures and suitable for various tasks such as segmentation or object recognition.
Glial cell migration in the eye disc.
Silies, Marion; Yuva, Yeliz; Engelen, Daniel; Aho, Annukka; Stork, Tobias; Klämbt, Christian
2007-11-28
Any complex nervous system is made out of two major cell types, neurons and glial cells. A hallmark of glial cells is their pronounced ability to migrate. En route to their final destinations, glial cells are generally guided by neuronal signals. Here we show that in the developing visual system of Drosophila glial cell migration is largely controlled by glial-glial interactions and occurs independently of axonal contact. Differentiation into wrapping glia is initiated close to the morphogenetic furrow. Using single cell labeling experiments we identified six distinct glial cell types in the eye disc. The migratory glial population is separated from the wrapping glial cells by the so-called carpet cells, extraordinary large glial cells, each covering a surface area of approximately 10,000 epithelial cells. Subsequent cell ablation experiments demonstrate that the carpet glia regulates glial migration in the eye disc epithelium and suggest a new model underlying glial migration and differentiation in the developing visual system.
Quentin, Romain; Elkin Frankston, Seth; Vernet, Marine; Toba, Monica N.; Bartolomeo, Paolo; Chanes, Lorena; Valero-Cabré, Antoni
2016-01-01
Behavioral and electrophysiological studies in humans and non-human primates have correlated frontal high-beta activity with the orienting of endogenous attention and shown the ability of the latter function to modulate visual performance. We here combined rhythmic transcranial magnetic stimulation (TMS) and diffusion imaging to study the relation between frontal oscillatory activity and visual performance, and we associated these phenomena to a specific set of white matter pathways that in humans subtend attentional processes. High-beta rhythmic activity on the right frontal eye field (FEF) was induced with TMS and its causal effects on a contrast sensitivity function were recorded to explore its ability to improve visual detection performance across different stimulus contrast levels. Our results show that frequency-specific activity patterns engaged in the right FEF have the ability to induce a leftward shift of the psychometric function. This increase in visual performance across different levels of stimulus contrast is likely mediated by a contrast gain mechanism. Interestingly, microstructural measures of white matter connectivity suggest a strong implication of right fronto-parietal connectivity linking the FEF and the intraparietal sulcus in propagating high-beta rhythmic signals across brain networks and subtending top-down frontal influences on visual performance. PMID:25899709
White matter changes linked to visual recovery after nerve decompression
Paul, David A.; Gaffin-Cahn, Elon; Hintz, Eric B.; Adeclat, Giscard J.; Zhu, Tong; Williams, Zoë R.; Vates, G. Edward; Mahon, Bradford Z.
2015-01-01
The relationship between the integrity of white matter tracts and cortical function in the human brain remains poorly understood. Here we use a model of reversible white matter injury, compression of the optic chiasm by tumors of the pituitary gland, to study the structural and functional changes that attend spontaneous recovery of cortical function and visual abilities after surgical tumor removal and subsequent decompression of the nerves. We show that compression of the optic chiasm leads to demyelination of the optic tracts, which reverses as quickly as 4 weeks after nerve decompression. Furthermore, variability across patients in the severity of demyelination in the optic tracts predicts visual ability and functional activity in early cortical visual areas, and pre-operative measurements of myelination in the optic tracts predicts the magnitude of visual recovery after surgery. These data indicate that rapid regeneration of myelin in the human brain is a significant component of the normalization of cortical activity, and ultimately the recovery of sensory and cognitive function, after nerve decompression. More generally, our findings demonstrate the utility of diffusion tensor imaging as an in vivo measure of myelination in the human brain. PMID:25504884
Wave energy and intertidal productivity
Leigh, Egbert G.; Paine, Robert T.; Quinn, James F.; Suchanek, Thomas H.
1987-01-01
In the northeastern Pacific, intertidal zones of the most wave-beaten shores receive more energy from breaking waves than from the sun. Despite severe mortality from winter storms, communities at some wave-beaten sites produce an extraordinary quantity of dry matter per unit area of shore per year. At wave-beaten sites of Tatoosh Island, WA, sea palms, Postelsia palmaeformis, can produce > 10 kg of dry matter, or 1.5 × 108 J, per m2 in a good year. Extraordinarily productive organisms such as Postelsia are restricted to wave-beaten sites. Intertidal organisms cannot transform wave energy into chemical energy, as photosynthetic plants transform solar energy, nor can intertidal organisms “harness” wave energy. Nonetheless, wave energy enhances the productivity of intertidal organisms. On exposed shores, waves increase the capacity of resident algae to acquire nutrients and use sunlight, augment the competitive ability of productive organisms, and protect intertidal residents by knocking away their enemies or preventing them from feeding. PMID:16593813
Method Matters: Systematic Effects of Testing Procedure on Visual Working Memory Sensitivity
ERIC Educational Resources Information Center
Makovski, Tal; Watson, Leah M.; Koutstaal, Wilma; Jiang, Yuhong V.
2010-01-01
Visual working memory (WM) is traditionally considered a robust form of visual representation that survives changes in object motion, observer's position, and other visual transients. This article presents data that are inconsistent with the traditional view. We show that memory sensitivity is dramatically influenced by small variations in the…
A foundation for savantism? Visuo-spatial synaesthetes present with cognitive benefits.
Simner, Julia; Mayo, Neil; Spiller, Mary-Jane
2009-01-01
Individuals with 'time-space' synaesthesia have conscious awareness of mappings between time and space (e.g., they may see months arranged in an ellipse, or years as columns or spirals). These mappings exist in the 3D space around the body or in a virtual space within the mind's eye. Our study shows that these extra-ordinary mappings derive from, or give rise to, superior abilities in the two domains linked by this cross-modal phenomenon (i.e., abilities relating to time, and visualised space). We tested ten time-space synaesthetes with a battery of temporal and visual/spatial tests. Our temporal battery (the Edinburgh [Public and Autobiographical] Events Battery - EEB) assessed both autobiographical and non-autobiographical memory for events. Our visual/spatial tests assessed the ability to manipulate real or imagined objects in 3D space (the Three Dimensional Constructional Praxis test; Visual Object and Space Perception Battery, University of Southern California Mental Rotation Test) as well as assessing visual memory recall (Visual Patterns Test - VPT). Synaesthetes' performance was superior to the control population in every assessment, but was not superior in tasks that do not draw upon abilities related to their mental calendars. Our paper discusses the implications of this temporal-spatial advantage as it relates to normal processing, synaesthetic processing, and to the savant-like condition of hyperthymestic syndrome (Parker et al., 2006).
Development of pan-Arctic database for river chemistry
McClelland, J.W.; Holmes, R.M.; Peterson, B.J.; Amon, R.; Brabets, T.; Cooper, L.; Gibson, J.; Gordeev, V.V.; Guay, C.; Milburn, D.; Staples, R.; Raymond, P.A.; Shiklomanov, I.; Striegl, Robert G.; Zhulidov, A.; Gurtovaya, T.; Zimov, S.
2008-01-01
More than 10% of all continental runoff flows into the Arctic Ocean. This runoff is a dominant feature of the Arctic Ocean with respect to water column structure and circulation. Yet understanding of the chemical characteristics of runoff from the pan-Arctic watershed is surprisingly limited. The Pan- Arctic River Transport of Nutrients, Organic Matter, and Suspended Sediments ( PARTNERS) project was initiated in 2002 to help remedy this deficit, and an extraordinary data set has emerged over the past few years as a result of the effort. This data set is publicly available through the Cooperative Arctic Data and Information Service (CADIS) of the Arctic Observing Network (AON). Details about data access are provided below.
von Noorden, G K
1990-01-01
Animal experiments have explored the structural and functional alterations of the afferent visual pathways in amblyopia and have emphasized the extraordinary sensitivity of the immature visual system to abnormal visual stimulation. The practical consequences of these experiments are obvious: early diagnosis of amblyopia and energetic occlusion therapy as early in life as possible. At the same time, measures must be taken to prevent visual deprivation amblyopia in the occluded eye. After successful treatment, alternating penalization with two pairs of spectacles is recommended. Pleoptics involves an enormous commitment in terms of time, personnel and costs. In view of the fact that the superiority of this treatment over occlusion therapy has yet to be proven, the current value of pleoptics appears dubious. Moreover, overtreated patients may end up with intractable diplopia. Diverging opinions exist with regard to the use of penalization as a primary treatment of amblyopia. We employ it only in special cases as an alternative to occlusion therapy. Visual deprivation in infancy caused by opacities of the ocular media, especially when they occur unilaterally, must be eliminated, and deprivation amblyopia must be treated without delay to regain useful vision. Brief periods of bilateral occlusion are recommended to avoid the highly amblyopiogenic imbalance between binocular afferent visual input. Future developments will hopefully include new objective methods to diagnose amblyopia in preverbal children and infants. The application of positron emission tomography is perhaps the first step in the direction of searching for new approaches to this problem.(ABSTRACT TRUNCATED AT 250 WORDS)
May, Paul W; Cotton, Simon A; Harrison, Karl; Rzepa, Henry S
2017-03-29
The Molecule of the Month website (http://www.chm.bris.ac.uk/motm/motm.htm) is an educational resource that is celebrating its 20th anniversary. Here we reflect on its pioneering role in promoting new technology for visualizing and presenting chemical information on the web, as well as its achievements, as a free educational resource, both as a teaching aid and as a multi-user, multi-author learning platform. We discuss the legal aspects of such sites, as well as issues around how to make the content permanent. Finally, we look forward to how such sites may evolve in the future.
Visual imagery and functional connectivity in blindness: a single-case study
Boucard, Christine C.; Rauschecker, Josef P.; Neufang, Susanne; Berthele, Achim; Doll, Anselm; Manoliu, Andrej; Riedl, Valentin; Sorg, Christian; Wohlschläger, Afra; Mühlau, Mark
2016-01-01
We present a case report on visual brain plasticity after total blindness acquired in adulthood. SH lost her sight when she was 27. Despite having been totally blind for 43 years, she reported to strongly rely on her vivid visual imagery. Three-Tesla magnetic resonance imaging (MRI) of SH and age-matched controls was performed. The MRI sequence included anatomical MRI, resting-state functional MRI, and task-related functional MRI where SH was instructed to imagine colours, faces, and motion. Compared to controls, voxel-based analysis revealed white matter loss along SH's visual pathway as well as grey matter atrophy in the calcarine sulci. Yet we demonstrated activation in visual areas, including V1, using functional MRI. Of the four identified visual resting-state networks, none showed alterations in spatial extent; hence, SH's preserved visual imagery seems to be mediated by intrinsic brain networks of normal extent. Time courses of two of these networks showed increased correlation with that of the inferior posterior default mode network, which may reflect adaptive changes supporting SH's strong internal visual representations. Overall, our findings demonstrate that conscious visual experience is possible even after years of absence of extrinsic input. PMID:25690326
Visual imagery and functional connectivity in blindness: a single-case study.
Boucard, Christine C; Rauschecker, Josef P; Neufang, Susanne; Berthele, Achim; Doll, Anselm; Manoliu, Andrej; Riedl, Valentin; Sorg, Christian; Wohlschläger, Afra; Mühlau, Mark
2016-05-01
We present a case report on visual brain plasticity after total blindness acquired in adulthood. SH lost her sight when she was 27. Despite having been totally blind for 43 years, she reported to strongly rely on her vivid visual imagery. Three-Tesla magnetic resonance imaging (MRI) of SH and age-matched controls was performed. The MRI sequence included anatomical MRI, resting-state functional MRI, and task-related functional MRI where SH was instructed to imagine colours, faces, and motion. Compared to controls, voxel-based analysis revealed white matter loss along SH's visual pathway as well as grey matter atrophy in the calcarine sulci. Yet we demonstrated activation in visual areas, including V1, using functional MRI. Of the four identified visual resting-state networks, none showed alterations in spatial extent; hence, SH's preserved visual imagery seems to be mediated by intrinsic brain networks of normal extent. Time courses of two of these networks showed increased correlation with that of the inferior posterior default mode network, which may reflect adaptive changes supporting SH's strong internal visual representations. Overall, our findings demonstrate that conscious visual experience is possible even after years of absence of extrinsic input.
14 CFR Section 17 - Objective Classification-Extraordinary Items
Code of Federal Regulations, 2010 CFR
2010-01-01
... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Objective Classification-Extraordinary Items Section 17 Section 17 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION... AIR CARRIERS Profit and Loss Classification Section 17 Objective Classification—Extraordinary Items...
Code of Federal Regulations, 2010 CFR
2010-04-01
... States, signed on December 17, 1992; or, with respect to binational panel or extraordinary challenge proceedings underway as of such date, or any binational panel or extraordinary challenge proceedings that may..., as prescribed by the Ley de Comercio Exterior and its regulations; (p) Extraordinary challenge...
Energy behaviour of extraordinary waves in magnetized quantum plasmas
NASA Astrophysics Data System (ADS)
Moradi, Afshin
2018-05-01
We study the storage and flow of energy in a homogeneous magnetized quantum electron plasma that occurs when an elliptically polarized extraordinary electromagnetic wave propagates in the system. Expressions for the stored energy, energy flow, and energy velocity of extraordinary electromagnetic waves are derived by means of the quantum magnetohydrodynamics theory in conjunction with the Maxwell equations. Numerical results show that the energy flow of the high-frequency mode of extraordinary wave is modified only due to the Bohm potential in the short wavelength limit.
Modi, Shilpi; Bhattacharya, Manisha; Singh, Namita; Tripathi, Rajendra Prasad; Khushu, Subash
2012-10-01
To investigate structural reorganization in the brain with differential visual experience using Voxel-Based Morphometry with Diffeomorphic Anatomic Registration Through Exponentiated Lie algebra algorithm (DARTEL) approach. High resolution structural MR images were taken in fifteen normal sighted healthy controls, thirteen totally blind subjects and six partial blind subjects. The analysis was carried out using SPM8 software on MATLAB 7.6.0 platform. VBM study revealed gray matter volume atrophy in the cerebellum and left inferior parietal cortex in total blind subjects and in left inferior parietal cortex, right caudate nucleus, and left primary visual cortex in partial blind subjects as compared to controls. White matter volume loss was found in calcarine gyrus in total blind subjects and Thlamus-somatosensory region in partially blind subjects as compared to controls. Besides, an increase in Gray Matter volume was also found in left middle occipital and middle frontal gyrus and right entorhinal cortex, and an increase in White Matter volume was found in superior frontal gyrus, left middle temporal gyrus and right Heschl's gyrus in totally blind subjects as compared to controls. Comparison between total and partial blind subjects revealed a greater Gray Matter volume in left cerebellum of partial blinds and left Brodmann area 18 of total blind subjects. Results suggest that, loss of vision at an early age can induce significant structural reorganization on account of the loss of visual input. These plastic changes are different in early onset of total blindness as compared to partial blindness. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.
22 CFR 61.6 - Consultation with subject matter specialists.
Code of Federal Regulations, 2014 CFR
2014-04-01
... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Consultation with subject matter specialists. 61.6 Section 61.6 Foreign Relations DEPARTMENT OF STATE PUBLIC DIPLOMACY AND EXCHANGES WORLD-WIDE FREE FLOW OF AUDIO-VISUAL MATERIALS § 61.6 Consultation with subject matter specialists. (a) The...
22 CFR 61.6 - Consultation with subject matter specialists.
Code of Federal Regulations, 2012 CFR
2012-04-01
... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Consultation with subject matter specialists. 61.6 Section 61.6 Foreign Relations DEPARTMENT OF STATE PUBLIC DIPLOMACY AND EXCHANGES WORLD-WIDE FREE FLOW OF AUDIO-VISUAL MATERIALS § 61.6 Consultation with subject matter specialists. (a) The...
22 CFR 61.6 - Consultation with subject matter specialists.
Code of Federal Regulations, 2013 CFR
2013-04-01
... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Consultation with subject matter specialists. 61.6 Section 61.6 Foreign Relations DEPARTMENT OF STATE PUBLIC DIPLOMACY AND EXCHANGES WORLD-WIDE FREE FLOW OF AUDIO-VISUAL MATERIALS § 61.6 Consultation with subject matter specialists. (a) The...
22 CFR 61.6 - Consultation with subject matter specialists.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Consultation with subject matter specialists. 61.6 Section 61.6 Foreign Relations DEPARTMENT OF STATE PUBLIC DIPLOMACY AND EXCHANGES WORLD-WIDE FREE FLOW OF AUDIO-VISUAL MATERIALS § 61.6 Consultation with subject matter specialists. (a) The...
22 CFR 61.6 - Consultation with subject matter specialists.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Consultation with subject matter specialists. 61.6 Section 61.6 Foreign Relations DEPARTMENT OF STATE PUBLIC DIPLOMACY AND EXCHANGES WORLD-WIDE FREE FLOW OF AUDIO-VISUAL MATERIALS § 61.6 Consultation with subject matter specialists. (a) The...
29 CFR 4043.31 - Extraordinary dividend or stock redemption.
Code of Federal Regulations, 2014 CFR
2014-07-01
... TERMINATIONS REPORTABLE EVENTS AND CERTAIN OTHER NOTIFICATION REQUIREMENTS Post-Event Notice of Reportable Events § 4043.31 Extraordinary dividend or stock redemption. (a) Reportable event. A reportable event...) Extraordinary dividends and stock redemptions. The reportable event described in section 4043(c)(11) of ERISA...
Visual Masking During Pursuit Eye Movements
ERIC Educational Resources Information Center
White, Charles W.
1976-01-01
Visual masking occurs when one stimulus interferes with the perception of another stimulus. Investigates which matters more for visual masking--that the target and masking stimuli are flashed on the same part of the retina, or, that the target and mask appear in the same place. (Author/RK)
45 CFR 96.134 - Maintenance of effort regarding State expenditures.
Code of Federal Regulations, 2010 CFR
2010-10-01
... extraordinary economic conditions in the State justify the waiver. The State involved must submit information sufficient for the Secretary to make the determination, including the nature of the extraordinary economic... be applicable only to the fiscal year involved. “Extraordinary economic conditions” mean a financial...
40 CFR 80.73 - Inability to produce conforming gasoline in extraordinary circumstances.
Code of Federal Regulations, 2011 CFR
2011-07-01
... gasoline in extraordinary circumstances. 80.73 Section 80.73 Protection of Environment ENVIRONMENTAL... Gasoline § 80.73 Inability to produce conforming gasoline in extraordinary circumstances. In appropriate..., for a brief period, to distribute gasoline which does not meet the requirements for reformulated...
40 CFR 80.73 - Inability to produce conforming gasoline in extraordinary circumstances.
Code of Federal Regulations, 2012 CFR
2012-07-01
... gasoline in extraordinary circumstances. 80.73 Section 80.73 Protection of Environment ENVIRONMENTAL... Gasoline § 80.73 Inability to produce conforming gasoline in extraordinary circumstances. In appropriate..., for a brief period, to distribute gasoline which does not meet the requirements for reformulated...
40 CFR 80.73 - Inability to produce conforming gasoline in extraordinary circumstances.
Code of Federal Regulations, 2010 CFR
2010-07-01
... gasoline in extraordinary circumstances. 80.73 Section 80.73 Protection of Environment ENVIRONMENTAL... Gasoline § 80.73 Inability to produce conforming gasoline in extraordinary circumstances. In appropriate..., for a brief period, to distribute gasoline which does not meet the requirements for reformulated...
40 CFR 80.73 - Inability to produce conforming gasoline in extraordinary circumstances.
Code of Federal Regulations, 2014 CFR
2014-07-01
... gasoline in extraordinary circumstances. 80.73 Section 80.73 Protection of Environment ENVIRONMENTAL... Gasoline § 80.73 Inability to produce conforming gasoline in extraordinary circumstances. In appropriate..., for a brief period, to distribute gasoline which does not meet the requirements for reformulated...
40 CFR 80.73 - Inability to produce conforming gasoline in extraordinary circumstances.
Code of Federal Regulations, 2013 CFR
2013-07-01
... gasoline in extraordinary circumstances. 80.73 Section 80.73 Protection of Environment ENVIRONMENTAL... Gasoline § 80.73 Inability to produce conforming gasoline in extraordinary circumstances. In appropriate..., for a brief period, to distribute gasoline which does not meet the requirements for reformulated...
40 CFR 92.11 - Compliance with emission standards in extraordinary circumstances.
Code of Federal Regulations, 2010 CFR
2010-07-01
... standards in extraordinary circumstances. The provisions of this section are intended to address problems... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Compliance with emission standards in extraordinary circumstances. 92.11 Section 92.11 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY...
Children's Understanding of Ordinary and Extraordinary Minds
ERIC Educational Resources Information Center
Lane, Jonathan D.; Wellman, Henry M.; Evans, E. Margaret
2010-01-01
How and when do children develop an understanding of extraordinary mental capacities? The current study tested 56 preschoolers on false-belief and knowledge-ignorance tasks about the mental states of contrasting agents--some agents were ordinary humans, some had exceptional perceptual capacities, and others possessed extraordinary mental…
DNA Free Energy Landscapes and RNA Nano-Self-Assembly Using Atomic Force Microscopy
NASA Astrophysics Data System (ADS)
Frey, Eric William
There is an important conceptual lesson which has long been appreciated by those who work in biophysics and related interdisciplinary fields. While the extraordinary behavior of biological matter is governed by its detailed atomic structure and random fluctuations, and is therefore difficult to predict, it can nevertheless be understood within simplified frameworks. Such frameworks model the system as consisting of only one or a few components, and model the behavior of the system as the occupation of a single state out of a small number of states available. The emerging widespread application of nanotechnology, such as atomic force microscopy (AFM), has expanded this understanding in eye-opening new levels of detail by enabling nano-scale control, measurement, and visualization of biological molecules. This thesis describes two independent projects, both of which illuminate this understanding using AFM, but which do so from very different perspectives. The organization of this thesis is as follows. Chapter 1 begins with an experimental background and introduction to AFM, and then describes our setup in both single-molecule manipulation and imaging modes. In Chapter 2, we describe the first project, the motivation for which is to extend methods for the experimental determination of the free energy landscape of a molecule. This chapter relies on the analysis of single-molecule manipulation data. Chapter 3 describes the second project, the motivation for which is to create RNA-based nano-structures suitable for future applications in living mammalian cells. This chapter relies mainly on imaging. Chapters 2 and 3 can thus be read and understood separately.
Neural control and precision of flight muscle activation in Drosophila.
Lehmann, Fritz-Olaf; Bartussek, Jan
2017-01-01
Precision of motor commands is highly relevant in a large context of various locomotor behaviors, including stabilization of body posture, heading control and directed escape responses. While posture stability and heading control in walking and swimming animals benefit from high friction via ground reaction forces and elevated viscosity of water, respectively, flying animals have to cope with comparatively little aerodynamic friction on body and wings. Although low frictional damping in flight is the key to the extraordinary aerial performance and agility of flying birds, bats and insects, it challenges these animals with extraordinary demands on sensory integration and motor precision. Our review focuses on the dynamic precision with which Drosophila activates its flight muscular system during maneuvering flight, considering relevant studies on neural and muscular mechanisms of thoracic propulsion. In particular, we tackle the precision with which flies adjust power output of asynchronous power muscles and synchronous flight control muscles by monitoring muscle calcium and spike timing within the stroke cycle. A substantial proportion of the review is engaged in the significance of visual and proprioceptive feedback loops for wing motion control including sensory integration at the cellular level. We highlight that sensory feedback is the basis for precise heading control and body stability in flies.
Aspillaga, Eneko; Bartumeus, Frederic; Linares, Cristina; Starr, Richard M; López-Sanz, Àngel; Díaz, David; Zabala, Mikel; Hereu, Bernat
2016-01-01
It is important to account for the movement behaviour of fishes when designing effective marine protected areas (MPAs). Fish movements occur across different spatial and temporal scales and understanding the variety of movements is essential to make correct management decisions. This study describes in detail the movement patterns of an economically and commercially important species, Diplodus sargus, within a well-enforced Mediterranean MPA. We monitored horizontal and vertical movements of 41 adult individuals using passive acoustic telemetry for up to one year. We applied novel analysis and visualization techniques to get a comprehensive view of a wide range of movements. D. sargus individuals were highly territorial, moving within small home ranges (< 1 km2), inside which they displayed repetitive diel activity patterns. Extraordinary movements beyond the ordinary home range were observed under two specific conditions. First, during stormy events D. sargus presented a sheltering behaviour, moving to more protected places to avoid the disturbance. Second, during the spawning season they made excursions to deep areas (> 50 m), where they aggregated to spawn. This study advances our understanding about the functioning of an established MPA and provides important insights into the biology and management of a small sedentary species, suggesting the relevance of rare but important fish behaviours.
Aspillaga, Eneko; Bartumeus, Frederic; Linares, Cristina; Starr, Richard M.; López-Sanz, Àngel; Díaz, David; Zabala, Mikel; Hereu, Bernat
2016-01-01
It is important to account for the movement behaviour of fishes when designing effective marine protected areas (MPAs). Fish movements occur across different spatial and temporal scales and understanding the variety of movements is essential to make correct management decisions. This study describes in detail the movement patterns of an economically and commercially important species, Diplodus sargus, within a well-enforced Mediterranean MPA. We monitored horizontal and vertical movements of 41 adult individuals using passive acoustic telemetry for up to one year. We applied novel analysis and visualization techniques to get a comprehensive view of a wide range of movements. D. sargus individuals were highly territorial, moving within small home ranges (< 1 km2), inside which they displayed repetitive diel activity patterns. Extraordinary movements beyond the ordinary home range were observed under two specific conditions. First, during stormy events D. sargus presented a sheltering behaviour, moving to more protected places to avoid the disturbance. Second, during the spawning season they made excursions to deep areas (> 50 m), where they aggregated to spawn. This study advances our understanding about the functioning of an established MPA and provides important insights into the biology and management of a small sedentary species, suggesting the relevance of rare but important fish behaviours. PMID:27437692
Ranjan, Manish; Boutet, Alexandre; Xu, David S; Lozano, Christopher S; Kumar, Rajeev; Fasano, Alfonso; Kucharczyk, Walter; Lozano, Andres M
2018-05-30
The visualization of the subthalamic nucleus (STN) on magnetic resonance imaging (MRI) is variable. Studies of the contribution of patient-related factors and intrinsic brain volumetrics to STN visualization have not been reported previously. To assess the visualization of the STN during deep brain stimulation (DBS) surgery in a clinical setting. Eighty-two patients undergoing pre-operative MRI to plan for STN DBS for Parkinson disease were retrospectively studied. The visualization of the STN and its borders was assessed and scored by 3 independent observers using a 4-point ordinal scale (from 0 = not seen to 3 = excellent visualization). This measure was then correlated with the patients' clinical information and brain volumes. The mean STN visualization scores were 1.68 and 1.63 for the right and left STN, respectively, with a good interobserver reliability (intraclass correlation coefficient: 0.744). Older age and decreased white matter volume were negatively correlated with STN visualization (p < 0.05). STN visualization is only fair to good on routine MRI with good concordance of interindividual rating. Advancing age and decreased white matter are associated with poor visualization of the STN. Knowledge about factors contributing to poor visualization of the STN could alert a surgeon to modify the imaging strategy to optimize surgical targeting. © 2018 S. Karger AG, Basel.
22 CFR 41.55 - Aliens with extraordinary ability.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Aliens with extraordinary ability. 41.55... IMMIGRATION AND NATIONALITY ACT, AS AMENDED Business and Media Visas § 41.55 Aliens with extraordinary ability. (a) Requirements for O classification. An alien shall be classifiable under the provisions of INA 101...
22 CFR 41.55 - Aliens with extraordinary ability.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Aliens with extraordinary ability. 41.55... IMMIGRATION AND NATIONALITY ACT, AS AMENDED Business and Media Visas § 41.55 Aliens with extraordinary ability. (a) Requirements for O classification. An alien shall be classifiable under the provisions of INA 101...
22 CFR 41.55 - Aliens with extraordinary ability.
Code of Federal Regulations, 2014 CFR
2014-04-01
... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Aliens with extraordinary ability. 41.55... IMMIGRATION AND NATIONALITY ACT, AS AMENDED Business and Media Visas § 41.55 Aliens with extraordinary ability. (a) Requirements for O classification. An alien shall be classifiable under the provisions of INA 101...
22 CFR 41.55 - Aliens with extraordinary ability.
Code of Federal Regulations, 2013 CFR
2013-04-01
... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Aliens with extraordinary ability. 41.55... IMMIGRATION AND NATIONALITY ACT, AS AMENDED Business and Media Visas § 41.55 Aliens with extraordinary ability. (a) Requirements for O classification. An alien shall be classifiable under the provisions of INA 101...
22 CFR 41.55 - Aliens with extraordinary ability.
Code of Federal Regulations, 2012 CFR
2012-04-01
... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Aliens with extraordinary ability. 41.55... IMMIGRATION AND NATIONALITY ACT, AS AMENDED Business and Media Visas § 41.55 Aliens with extraordinary ability. (a) Requirements for O classification. An alien shall be classifiable under the provisions of INA 101...
ERIC Educational Resources Information Center
Moloshavenko, Vera L.; Prozorova, Galina V.; Sienkiewicz, Lyudmila B.
2016-01-01
The article presents the experimentation on graduates' readiness formation to act in extraordinary situations conducted in the Tyumen Industrial University in training bachelors in "Oil and Gas Business". The criteria of graduates' readiness formation to act in extraordinary situations are the following: practicability, validity,…
7 CFR 1767.24 - Extraordinary items.
Code of Federal Regulations, 2010 CFR
2010-01-01
....1Cumulative Effect on Prior Years of a Change in Accounting Principle Extraordinary Items 434Extraordinary... on Prior Years of a Change in Accounting Principle This account shall include the cumulative effect on margins of prior periods as a result of a change in accounting principle from one that is no...
47 CFR 32.7600 - Extraordinary items.
Code of Federal Regulations, 2010 CFR
2010-10-01
... items, if reported other than as extraordinary items. (c) This account shall be charged or credited and Account 4070, Income taxes—accrued, shall be credited or charged for all current income tax effects (Federal, state and local) of extraordinary items. (d) This account shall also be charged or credited, as...
From Iconic to Lingual: Interpreting Visual Statements.
ERIC Educational Resources Information Center
Curtiss, Deborah
In this age of proliferating visual communications, there is a permissiveness in subject matter, content, and meaning that is exhilarating, yet overwhelming to interpret in a meaningful or consensual way. By recognizing visual statements, whether a piece of sculpture, an advertisement, a video, or a building, as communication, one can approach…
Quantitative analysis of diffusion tensor orientation: theoretical framework.
Wu, Yu-Chien; Field, Aaron S; Chung, Moo K; Badie, Benham; Alexander, Andrew L
2004-11-01
Diffusion-tensor MRI (DT-MRI) yields information about the magnitude, anisotropy, and orientation of water diffusion of brain tissues. Although white matter tractography and eigenvector color maps provide visually appealing displays of white matter tract organization, they do not easily lend themselves to quantitative and statistical analysis. In this study, a set of visual and quantitative tools for the investigation of tensor orientations in the human brain was developed. Visual tools included rose diagrams, which are spherical coordinate histograms of the major eigenvector directions, and 3D scatterplots of the major eigenvector angles. A scatter matrix of major eigenvector directions was used to describe the distribution of major eigenvectors in a defined anatomic region. A measure of eigenvector dispersion was developed to describe the degree of eigenvector coherence in the selected region. These tools were used to evaluate directional organization and the interhemispheric symmetry of DT-MRI data in five healthy human brains and two patients with infiltrative diseases of the white matter tracts. In normal anatomical white matter tracts, a high degree of directional coherence and interhemispheric symmetry was observed. The infiltrative diseases appeared to alter the eigenvector properties of affected white matter tracts, showing decreased eigenvector coherence and interhemispheric symmetry. This novel approach distills the rich, 3D information available from the diffusion tensor into a form that lends itself to quantitative analysis and statistical hypothesis testing. (c) 2004 Wiley-Liss, Inc.
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Klinger, Daniel R; Reinard, Kevin A; Ajayi, Olaide O; Delashaw, Johnny B
2018-01-01
The binocular operating microscope has been the visualization instrument of choice for microsurgical clipping of intracranial aneurysms for many decades. To discuss recent technological advances that have provided novel visualization tools, which may prove to be superior to the binocular operating microscope in many regards. We present an operative video and our operative experience with the BrightMatterTM Servo System (Synaptive Medical, Toronto, Ontario, Canada) during the microsurgical clipping of an anterior communicating artery aneurysm. To the best of our knowledge, the use of this device for the microsurgical clipping of an intracranial aneurysm has never been described in the literature. The BrightMatterTM Servo System (Synaptive Medical) is a surgical exoscope which avoids many of the ergonomic constraints of the binocular operating microscope, but is associated with a steep learning curve. The BrightMatterTM Servo System (Synaptive Medical) is a maneuverable surgical exoscope that is positioned with a directional aiming device and a surgeon-controlled foot pedal. While utilizing this device comes with a steep learning curve typical of any new technology, the BrightMatterTM Servo System (Synaptive Medical) has several advantages over the conventional surgical microscope, which include a relatively unobstructed surgical field, provision of high-definition images, and visualization of difficult angles/trajectories. This device can easily be utilized as a visualization tool for a variety of cranial and spinal procedures in lieu of the binocular operating microscope. We anticipate that this technology will soon become an integral part of the neurosurgeon's armamentarium. Copyright © 2017 by the Congress of Neurological Surgeons
Extraordinary SEAWs under influence of the spin-spin interaction and the quantum Bohm potential
NASA Astrophysics Data System (ADS)
Andreev, Pavel A.
2018-06-01
The separate spin evolution (SSE) of electrons causes the existence of the spin-electron acoustic wave. Extraordinary spin-electron acoustic waves (SEAWs) propagating perpendicular to the external magnetic field have a large contribution of the transverse electric field. Its spectrum has been studied in the quasi-classical limit at the consideration of the separate spin evolution. The spin-spin interaction and the quantum Bohm potential give contribution in the spectrum extraordinary SEAWs. This contribution is studied in this paper. Moreover, it is demonstrated that the spin-spin interaction leads to the existence of the extraordinary SEAWs if the SSE is neglected. It has been found that the SSE causes the instability of the extraordinary SEAW at the large wavelengths, but the quantum Bohm potential leads to the full stabilization of the spectrum.
ERIC Educational Resources Information Center
Fish, Kristine; Mun, Jungwon; A'Jontue, RoseAnn
2016-01-01
Educational webcasts or video lectures as a teaching tool and a form of visual aid have become widely used with the rising prevalence of online and blended courses and with the increase of web-based video materials. Thus, research pertaining to factors enhancing the effectiveness of video lectures, such as number of visual aids, is critical. This…
Higher integrity of the motor and visual pathways in long-term video game players.
Zhang, Yang; Du, Guijin; Yang, Yongxin; Qin, Wen; Li, Xiaodong; Zhang, Quan
2015-01-01
Long term video game players (VGPs) exhibit superior visual and motor skills compared with non-video game control subjects (NVGCs). However, the neural basis underlying the enhanced behavioral performance remains largely unknown. To clarify this issue, the present study compared the whiter matter integrity within the corticospinal tracts (CST), the superior longitudinal fasciculus (SLF), the inferior longitudinal fasciculus (ILF), and the inferior fronto-occipital fasciculus (IFOF) between the VGPs and the NVGCs using diffusion tensor imaging. Compared with the NVGCs, voxel-wise comparisons revealed significantly higher fractional anisotropy (FA) values in some regions within the left CST, left SLF, bilateral ILF, and IFOF in VGPs. Furthermore, higher FA values in the left CST at the level of cerebral peduncle predicted a faster response in visual attention tasks. These results suggest that higher white matter integrity in the motor and higher-tier visual pathways is associated with long-term video game playing, which may contribute to the understanding on how video game play influences motor and visual performance.
Higher integrity of the motor and visual pathways in long-term video game players
Du, Guijin; Yang, Yongxin; Qin, Wen; Li, Xiaodong; Zhang, Quan
2015-01-01
Long term video game players (VGPs) exhibit superior visual and motor skills compared with non-video game control subjects (NVGCs). However, the neural basis underlying the enhanced behavioral performance remains largely unknown. To clarify this issue, the present study compared the whiter matter integrity within the corticospinal tracts (CST), the superior longitudinal fasciculus (SLF), the inferior longitudinal fasciculus (ILF), and the inferior fronto-occipital fasciculus (IFOF) between the VGPs and the NVGCs using diffusion tensor imaging. Compared with the NVGCs, voxel-wise comparisons revealed significantly higher fractional anisotropy (FA) values in some regions within the left CST, left SLF, bilateral ILF, and IFOF in VGPs. Furthermore, higher FA values in the left CST at the level of cerebral peduncle predicted a faster response in visual attention tasks. These results suggest that higher white matter integrity in the motor and higher-tier visual pathways is associated with long-term video game playing, which may contribute to the understanding on how video game play influences motor and visual performance. PMID:25805981
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2012-08-07
... Due to Extraordinary Market Volatility, To Extend the Effective Date of the Pilot Until February 4... extraordinary market volatility, to extend the effective date of the pilot by which such rule operates from the... individual securities due to extraordinary market volatility, to extend the effective date of the pilot by...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-04
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2013-02-20
... to Address Extraordinary Market Volatility or February 4, 2014. The text of the proposed rule change... Extraordinary Market Volatility or February 4, 2014[3]. During the pilot, the term ``Circuit Breaker Securities... periods of extraordinary market volatility in S&P 500 stocks.\\3\\ The rules require the Listing Markets \\4...
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2013-02-20
... Regulation NMS Plan to Address Extraordinary Market Volatility or February 4, 2014. The Exchange will... of operations of the Regulation NMS Plan to Address Extraordinary Market Volatility or February 4... periods of extraordinary market volatility in S&P 500 stocks.\\3\\ The rules require the Listing Markets \\4...
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-08-03
... periods of extraordinary market volatility in S&P 500 stocks.\\3\\ The rules require the Listing Markets \\4... mechanism to address extraordinary market volatility, if adopted, applies.\\9\\ On June 23, 2011, the... to address extraordinary market volatility, and further extended the pilot period, so that the pilot...
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2013-02-20
... Extraordinary Market Volatility or February 4, 2014. The text of the proposed rule change is below. Proposed new... Extraordinary Market Volatility or February 4, 2014[3]. During the pilot, the term ``Circuit Breaker Securities... ``Exchanges''), to pause trading during periods of extraordinary market volatility in S&P 500 stocks.\\3\\ The...
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... Extraordinary Market Volatility, To Extend the Effective Date of the Pilot, Until February 4, 2013 August 1...--Equities, which provides for trading pauses in individual securities due to extraordinary market volatility... securities due to extraordinary market volatility, to extend the effective date of the pilot by which such...
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2012-01-27
... ``Exchanges''), to pause trading during periods of extraordinary market volatility in S&P 500 stocks.\\3\\ The... the date on which a limit up/limit down mechanism to address extraordinary market volatility, if... adoption of a limit up/limit down mechanism to address extraordinary market volatility, and further...
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2011-04-12
... Extraordinary Market Volatility, To Extend the Effective Date of the Pilot Until the Earlier of August 11, 2011 or the Date on Which a Limit Up/Limit Down Mechanism To Address Extraordinary Market Volatility, if... due to extraordinary market volatility, to extend the effective date of the pilot by which such rule...
Rapid heating of matter using high power lasers
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bang, Woosuk
2016-04-08
This slide presentation describes motivation (uniform and rapid heating of a target, opportunity to study warm dense matter, study of nuclear fusion reactions), rapid heating of matter with intense laser-driven ion beams, visualization of the expanding warm dense gold and diamond, and nuclear fusion experiments using high power lasers (direct heating of deuterium spheres (radius ~ 10nm) with an intense laser pulse.
ERIC Educational Resources Information Center
Argyropoulos, Vassilios; Sideridis, Georgios D.; Botsas, George; Padeliadu, Susana
2012-01-01
The purpose of the present study was to assess self-regulation of students with visual impairments across two academic subjects, language and math. The participants were 46 Greek students with visual impairments who completed self-regulation measures across the subject matters of language and math. Initially, the factorial validity of the scale…
Listening to Voices of Children with a Visual Impairment: A Focus Group Study
ERIC Educational Resources Information Center
Khadka, Jyoti; Ryan, Barbara; Margrain, Tom H.; Woodhouse, J. Margaret; Davies, Nathan
2012-01-01
The purpose of the study was to identify the educational, social and leisure activities and issues that matter to school children and young people with a visual impairment and to compare their lifestyle with fully sighted counterparts. Thirteen focus groups were conducted and the groups were stratified by age, gender, visual status and school…
ERIC Educational Resources Information Center
Keehner, Madeleine; Hegarty, Mary; Cohen, Cheryl; Khooshabeh, Peter; Montello, Daniel R.
2008-01-01
Three experiments examined the effects of interactive visualizations and spatial abilities on a task requiring participants to infer and draw cross sections of a three-dimensional (3D) object. The experiments manipulated whether participants could interactively control a virtual 3D visualization of the object while performing the task, and…
Resonance-dependent extraordinary reflection and transmission in PC-symmetric layered structure
NASA Astrophysics Data System (ADS)
Fang, Yun-tuan; Zhang, Yi-chi; Wang, Ji-Jun
2018-01-01
In order to achieve controllable enhanced reflection and transmission in part-time (PT) symmetric systems, we combine a cavity resonance effect with the layered PT-symmetric structure. At the resonance wavelength, except for the nonreciprocal extraordinary reflection, an enhanced transmission is also obtained. Both the extraordinary reflectance and transmittance are dependent on the modulation depth and period number in a discrete form.
Pathways to Seeing Music: Enhanced Structural Connectivity in Colored-Music Synesthesia
Zamm, Anna; Schlaug, Gottfried; Eagleman, David M.; Loui, Psyche
2013-01-01
Synesthesia, a condition in which a stimulus in one sensory modality consistently and automatically triggers concurrent percepts in another modality, provides a window into the neural correlates of cross-modal associations. While research on grapheme-color synesthesia has provided evidence for both hyperconnectivity/hyperbinding and disinhibited feedback as possible underlying mechanisms, less research has explored the neuroanatomical basis of other forms of synesthesia. In the current study we investigated the white matter correlates of colored-music synesthesia. As these synesthetes report seeing colors upon hearing musical sounds, we hypothesized they might show different patterns of connectivity between visual and auditory association areas. We used diffusion tensor imaging to trace the white matter tracts in temporal and occipital lobe regions in 10 synesthetes and 10 matched non-synesthete controls. Results showed that synesthetes possessed different hemispheric patterns of fractional anisotropy, an index of white matter integrity, in the inferior fronto-occipital fasciculus (IFOF), a major white matter pathway that connects visual and auditory association areas to frontal regions. Specifically, white matter integrity within the right IFOF was significantly greater in synesthetes than controls. Furthermore, white matter integrity in synesthetes was correlated with scores on audiovisual tests of the Synesthesia Battery, especially in white matter underlying the right fusiform gyrus. Our findings provide the first evidence of a white matter substrate of colored-music synesthesia, and suggest that enhanced white matter connectivity is involved in enhanced cross-modal associations. PMID:23454047
Weinstein, Joel M; Gilmore, Rick O; Shaikh, Sumera M; Kunselman, Allen R; Trescher, William V; Tashima, Lauren M; Boltz, Marianne E; McAuliffe, Matthew B; Cheung, Albert; Fesi, Jeremy D
2012-07-01
We sought to characterize visual motion processing in children with cerebral visual impairment (CVI) due to periventricular white matter damage caused by either hydrocephalus (eight individuals) or periventricular leukomalacia (PVL) associated with prematurity (11 individuals). Using steady-state visually evoked potentials (ssVEP), we measured cortical activity related to motion processing for two distinct types of visual stimuli: 'local' motion patterns thought to activate mainly primary visual cortex (V1), and 'global' or coherent patterns thought to activate higher cortical visual association areas (V3, V5, etc.). We studied three groups of children: (1) 19 children with CVI (mean age 9y 6mo [SD 3y 8mo]; 9 male; 10 female); (2) 40 neurologically and visually normal comparison children (mean age 9y 6mo [SD 3y 1mo]; 18 male; 22 female); and (3) because strabismus and amblyopia are common in children with CVI, a group of 41 children without neurological problems who had visual deficits due to amblyopia and/or strabismus (mean age 7y 8mo [SD 2y 8mo]; 28 male; 13 female). We found that the processing of global as opposed to local motion was preferentially impaired in individuals with CVI, especially for slower target velocities (p=0.028). Motion processing is impaired in children with CVI. ssVEP may provide useful and objective information about the development of higher visual function in children at risk for CVI. © The Authors. Journal compilation © Mac Keith Press 2011.
Whitaker, Kirstie J; Kang, Xiaojian; Herron, Timothy J; Woods, David L; Robertson, Lynn C; Alvarez, Bryan D
2014-04-15
In this study we show, for the first time, a correlation between the neuroanatomy of the synesthetic brain and a metric that measures behavior not exclusive to the synesthetic experience. Grapheme-color synesthetes (n=20), who experience colors triggered by viewing or thinking of specific letters or numbers, showed altered white matter microstructure, as measured using diffusion tensor imaging, compared with carefully matched non-synesthetic controls. Synesthetes had lower fractional anisotropy and higher perpendicular diffusivity when compared to non-synesthetic controls. An analysis of the mode of anisotropy suggested that these differences were likely due to the presence of more crossing pathways in the brains of synesthetes. Additionally, these differences in white matter microstructure correlated negatively, and only for synesthetes, with a measure of the vividness of their visual imagery. Synesthetes who reported the most vivid visual imagery had the lowest fractional anisotropy and highest perpendicular diffusivity. We conclude that synesthetes as a population vary along a continuum while showing categorical differences in neuroanatomy and behavior compared to non-synesthetes. Copyright © 2013 Elsevier Inc. All rights reserved.
The Effect of Time on the Stability of Iron Oxide Nanoparticles in Environmental Acids.
Rabajczyk, Anna; El Yamani, Naouale; Dusinska, Maria
2017-05-01
Advanced technologies seek for development of new materials and substances with extraordinary physicochemical properties at nanoscale level that boosts their increased use in everyday life. Manufacture of metal nanomaterials, including iron, carries the risk of their emission to surface waters. Suspended particulate matter (SPM) plays an important role in the transport of pollutants, such as metals which are an essential component of surface waters. The humic substances (HA), part of the SPM, interact with metal ions present in the aquatic environment. However, the previously available data on these compounds were obtained at the macro level and only scant information exist on nanomaterials. Thus, the present work has focused on the relationship between humic substances and nanosized particles, such as n-Fe2O3, in environmental acids.
End-of-life decision-making in India.
Freckelton, Ian
2014-09-01
The extraordinary circumstances and the tragic life of Aruna Shanbaug, together with the landmark Supreme Court of India decision in Shanbaug v Union of India (2011) 4 SCC 454, have provided a fillip and focus to debate within India about end-of-life decision-making. This extends to passive euthanasia, decision-making about withdrawal of nutrition, hydration and medical treatment from persons in a permanent vegetative or quasi-vegetative state, the role of the courts in such matters, the risks of corruption and misconduct, the criminal status of attempted suicide, and even the contentious issue of physician-assisted active euthanasia. The debates have been promoted further by important reports of the Law Commission of India. This editorial reviews the current state of the law and debate about such issues in India.
Next Generation Space Telescope
NASA Technical Reports Server (NTRS)
Mather, John; Stockman, H. S.; Fisher, Richard R. (Technical Monitor)
2000-01-01
The Next Generation Space Telescope (NGST), planned for launch in 2009, will be an 8-m class radiatively cooled infrared telescope at the Lagrange point L2. It will cover the wavelength range from 0.6 to 28 microns with cameras and spectrometers, to observe the first luminous objects after the Big Bang, and the formation, growth, clustering, and evolution of galaxies, stars, and protoplanetary clouds, leading to better understanding of our own Origins. It will seek evidence of the cosmic dark matter through its gravitational effects. With an aperture three times greater than the Hubble Space Telescope, it will provide extraordinary advances in capabilities and enable the discovery of many new phenomena. It is a joint project of the NASA, ESA, and CSA, and scientific operations will be provided by the Space Telescope Science Institute.
Chromophoric Nucleoside Analogues: Synthesis and Characterization of 6-Aminouracil-Based Nucleodyes.
Freeman, Noam S; Moore, Curtis E; Wilhelmsson, L Marcus; Tor, Yitzhak
2016-06-03
Nucleodyes, visibly colored chromophoric nucleoside analogues, are reported. Design criteria are outlined and the syntheses of cytidine and uridine azo dye analogues derived from 6-aminouracil are described. Structural analysis shows that the nucleodyes are sound structural analogues of their native nucleoside counterparts, and photophysical studies demonstrate that the nucleodyes are sensitive to microenvironmental changes. Quantum chemical calculations are presented as a valuable complementary tool for the design of strongly absorbing nucleodyes, which overlap with the emission of known fluorophores. Förster critical distance (R0) calculations determine that the nucleodyes make good FRET pairs with both 2-aminopurine (2AP) and pyrrolocytosine (PyC). Additionally, unique tautomerization features exhibited by 5-(4-nitrophenylazo)-6-oxocytidine (8) are visualized by an extraordinary crystal structure.
NASA World Wind, Open Source 4D Geospatial Visualization Platform: *.NET & Java* for EDUCATION
NASA Astrophysics Data System (ADS)
Hogan, P.; Kuehnel, F.
2006-12-01
NASA World Wind has only one goal, to provide the maximum opportunity for geospatial information to be experienced, be it education, science, research, business, or government. The benefits to understanding for information delivered in the context of its 4D virtual reality are extraordinary. The NASA World Wind visualization platform is open source and therefore lends itself well to being extended to service *any* requirements, be they proprietary and commercial or simply available. Data accessibility is highly optimized using standard formats including internationally certified open standards (W*S). Although proprietary applications can be built based on World Wind, and proprietary data delivered that leverage World Wind, there is nothing proprietary about the visualization platform itself or the multiple planetary data sets readily available, including global animations of live weather. NASA World Wind is being used by NASA research teams as well as being a formal part of high school and university curriculum. The National Guard uses World Wind for emergency response activities and State governments have incorporated high resolution imagery for GIS management as well as for their cross-agency emergency response activities. The U.S. federal government uses NASA World Wind for a myriad of GIS and security-related issues (NSA, NGA, DOE, FAA, etc.).
NASA World Wind, Open Source 4D Geospatial Visualization Platform: *.NET & Java*
NASA Astrophysics Data System (ADS)
Hogan, P.; Coughlan, J.
2006-12-01
NASA World Wind has only one goal, to provide the maximum opportunity for geospatial information to be experienced, be it education, science, research, business, or government. The benefits to understanding for information delivered in the context of its 4D virtual reality are extraordinary. The NASA World Wind visualization platform is open source and therefore lends itself well to being extended to service *any* requirements, be they proprietary and commercial or simply available. Data accessibility is highly optimized using standard formats including internationally certified open standards (W*S). Although proprietary applications can be built based on World Wind, and proprietary data delivered that leverage World Wind, there is nothing proprietary about the visualization platform itself or the multiple planetary data sets readily available, including global animations of live weather. NASA World Wind is being used by NASA research teams as well as being a formal part of high school and university curriculum. The National Guard uses World Wind for emergency response activities and State governments have incorporated high resolution imagery for GIS management as well as for their cross-agency emergency response activities. The U.S. federal government uses NASA World Wind for a myriad of GIS and security-related issues (NSA, NGA, DOE, FAA, etc.).
Jarick, Michelle; Dixon, Mike J; Stewart, Mark T; Maxwell, Emily C; Smilek, Daniel
2009-01-01
Synaesthesia is a fascinating condition whereby individuals report extraordinary experiences when presented with ordinary stimuli. Here we examined an individual (L) who experiences time units (i.e., months of the year and hours of the day) as occupying specific spatial locations (January is 30 degrees to the left of midline). This form of time-space synaesthesia has been recently investigated by Smilek et al. (2007) who demonstrated that synaesthetic time-space associations are highly consistent, occur regardless of intention, and can direct spatial attention. We extended this work by showing that for the synaesthete L, her time-space vantage point changes depending on whether the time units are seen or heard. For example, when L sees the word JANUARY, she reports experiencing January on her left side, however when she hears the word "January" she experiences the month on her right side. L's subjective reports were validated using a spatial cueing paradigm. The names of months were centrally presented followed by targets on the left or right. L was faster at detecting targets in validly cued locations relative to invalidly cued locations both for visually presented cues (January orients attention to the left) and for aurally presented cues (January orients attention to the right). We replicated this difference in visual and aural cueing effects using hour of the day. Our findings support previous research showing that time-space synaesthesia can bias visual spatial attention, and further suggest that for this synaesthete, time-space associations differ depending on whether they are visually or aurally induced.
48 CFR 750.7110-1 - Investigation.
Code of Federal Regulations, 2010 CFR
2010-10-01
... MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions To Protect Foreign Policy... statements of material facts within the knowledge of the individuals where documentary evidence is lacking...
Anomalous Faraday effect of a system with extraordinary optical transmittance.
Khanikaev, Alexander B; Baryshev, Alexander V; Fedyanin, Andrey A; Granovsky, Alexander B; Inoue, Mitsuteru
2007-05-28
It is shown theoretically that the Faraday rotation becomes anomalously large and exhibits extraordinary behavior near the frequencies of the extraordinary optical transmittance through optically thick perforated metal film with holes filled with a magneto-optically active material. This phenomenon is explained as result of strong confinement of the evanescent electromagnetic field within magnetic material, which occurs due to excitation of the coupled plasmon-polaritons on the opposite surfaces of the film.
Frontoparietal priority maps as biomarkers for mTBI
2016-10-01
spatial attention and eye movement deficits associated with mTBI result from disruption of the gray matter and/or the white matter in cortical...The hypothesis being tested is that spatial attention and eye movement deficits associated with mTBI result from disruption of the gray matter and/or...select agents Nothing to report. PRODUCTS o Publications, conference papers, and presentations “Visual Attention and Eye Movement Deficits in
ERIC Educational Resources Information Center
Caglayan, Günhan
2015-01-01
Despite few limitations, GeoGebra as a dynamic geometry software stood as a powerful instrument in helping university math majors understand, explore, and gain experiences in visualizing the limits of functions and the ?-d formalism. During the process of visualizing a theorem, the order mattered in the sequence of constituents. Students made use…
Deep grey matter growth predicts neurodevelopmental outcomes in very preterm children.
Young, Julia M; Powell, Tamara L; Morgan, Benjamin R; Card, Dallas; Lee, Wayne; Smith, Mary Lou; Sled, John G; Taylor, Margot J
2015-05-01
We evaluated whether the volume and growth rate of critical brain structures measured by MRI in the first weeks of life following very preterm (<32/40 weeks) birth could predict subsequent neurodevelopmental outcomes at 4 years of age. A significant proportion of children born very prematurely have cognitive deficits, but these problems are often only detected at early school age. Structural T2-weighted magnetic resonance images were acquired in 96 very preterm neonates scanned within 2 weeks of birth and 70 of these at term-equivalent age. An automated 3D image analysis procedure was used to measure the volume of selected brain structures across all scans and time points. At 4 years of age, 53 children returned for neuropsychological assessments evaluating IQ, language and visual motor integration. Associations with maternal education and perinatal measures were also explored. Multiple regression analyses revealed that growth of the caudate and globus pallidus between preterm birth and term-equivalent age predicted visual motor integration scores after controlling for sex and gestational age. Further associations were found between caudate and putamen growth with IQ and language scores. Analyses at either preterm or term-equivalent age only found associations between normalized deep grey matter growth and visual motor integration scores at term-equivalent age. Maternal education levels were associated with measures of IQ and language, but not visual motor integration. Thalamic growth was additionally linked with perinatal measures and presence of white matter lesions. These results highlight deep grey matter growth rates as promising biomarkers of long-term outcomes following very preterm birth, and contribute to our understanding of the brain-behaviour relations in these children. Copyright © 2015 Elsevier Inc. All rights reserved.
Modeling Early Galaxies Using Radiation Hydrodynamics
DOE Office of Scientific and Technical Information (OSTI.GOV)
None
This simulation uses a flux-limited diffusion solver to explore the radiation hydrodynamics of early galaxies, in particular, the ionizing radiation created by Population III stars. At the time of this rendering, the simulation has evolved to a redshift of 3.5. The simulation volume is 11.2 comoving megaparsecs, and has a uniform grid of 10243 cells, with over 1 billion dark matter and star particles. This animation shows a combined view of the baryon density, dark matter density, radiation energy and emissivity from this simulation. The multi-variate rendering is particularly useful because is shows both the baryonic matter ("normal") and darkmore » matter, and the pressure and temperature variables are properties of only the baryonic matter. Visible in the gas density are "bubbles", or shells, created by the radiation feedback from young stars. Seeing the bubbles from feedback provides confirmation of the physics model implemented. Features such as these are difficult to identify algorithmically, but easily found when viewing the visualization. Simulation was performed on Kraken at the National Institute for Computational Sciences. Visualization was produced using resources of the Argonne Leadership Computing Facility at Argonne National Laboratory.« less
Quasioptical devices based on extraordinary transmission at THz
NASA Astrophysics Data System (ADS)
Beruete, Miguel
2016-04-01
In this work I will present our latest advances in components developed from extraordinary transmission concepts operating at terahertz (THz) frequencies. First, a structure exhibiting two different extraordinary transmission resonances depending on the polarization of the incident wave will be shown. The peaks of transmission appear at approximately 2 and 2.5 THz for vertical and horizontal polarization, respectively, with a transmittance above 60% in both cases. Later on, a meandering line structure able to tune the extraordinary transmission resonance will be discussed. The operation frequency in this case is between 9 and 17 THz. A self-complementary polarizer will be then presented, with a high polarization purity. The fundamentals of this device based on the Babinet's principle will be discussed in depth. Finally, all these structures will be combined together to produce a dual-band Quarter Wave Plate able to convert a linear polarization at the input in a circular polarization at the output at two different bands, 1 and 2.2. THz. Some final words regarding the potential of extraordinary transmission for sensing applications will close the contribution.
Neurotheology-Matters of the Mind or Matters that Mind?
Shukla, Samarth; Acharya, Sourya; Rajput, Devendra
2013-07-01
Understanding the true nature of an individual, be it a child or an adult, a male or a female, is almost an impossible task. The vast abyss like behaviour of a human mind is virtually unfathomable. Yet, with the advent of neurosciences, it can be said that we, as the medical fraternity, have been in a position to decipher a considerable part of the human mind. This review accepts the fact that religion and theology have extreme reverence and respect. Yet, when it comes to extraordinary beliefs, phenomena, unimaginable feats and emotional deviations of the human mind, especially those which involve deep faiths and beliefs, comprehensive neuroscientific explanations from the emerging data, with the aid of elaborate neuroimaging, have proved to be extremely rational and logical. This review did make an attempt to untangle some facets of spirituality and to make rational explanations of the same. It was an attempt to understand the function of the mind (as an abstract) and the brain, on the spiritual experiences and sudden enlightments, the experience of togetherness with the universe, and to understand the phenomena of trance and an altered state of consciousness, which is better referred as the emerging science of neurotheology.
Neurotheology-Matters of the Mind or Matters that Mind?
Shukla, Samarth; Acharya, Sourya; Rajput, Devendra
2013-01-01
Understanding the true nature of an individual, be it a child or an adult, a male or a female, is almost an impossible task. The vast abyss like behaviour of a human mind is virtually unfathomable. Yet, with the advent of neurosciences, it can be said that we, as the medical fraternity, have been in a position to decipher a considerable part of the human mind. This review accepts the fact that religion and theology have extreme reverence and respect. Yet, when it comes to extraordinary beliefs, phenomena, unimaginable feats and emotional deviations of the human mind, especially those which involve deep faiths and beliefs, comprehensive neuroscientific explanations from the emerging data, with the aid of elaborate neuroimaging, have proved to be extremely rational and logical. This review did make an attempt to untangle some facets of spirituality and to make rational explanations of the same. It was an attempt to understand the function of the mind (as an abstract) and the brain, on the spiritual experiences and sudden enlightments, the experience of togetherness with the universe, and to understand the phenomena of trance and an altered state of consciousness, which is better referred as the emerging science of neurotheology. PMID:23998103
Beurskens, Rainer; Bock, Otmar
2013-12-01
Previous literature suggests that age-related deficits of dual-task walking are particularly pronounced with second tasks that require continuous visual processing. Here we evaluate whether the difficulty of the walking task matters as well. To this end, participants were asked to walk along a straight pathway of 20m length in four different walking conditions: (a) wide path and preferred pace; (b) narrow path and preferred pace, (c) wide path and fast pace, (d) obstacled wide path and preferred pace. Each condition was performed concurrently with a task requiring visual processing or fine motor control, and all tasks were also performed alone which allowed us to calculate the dual-task costs (DTC). Results showed that the age-related increase of DTC is substantially larger with the visually demanding than with the motor-demanding task, more so when walking on a narrow or obstacled path. We attribute these observations to the fact that visual scanning of the environment becomes more crucial when walking in difficult terrains: the higher visual demand of those conditions accentuates the age-related deficits in coordinating them with a visual non-walking task. Copyright © 2013 The Authors. Published by Elsevier B.V. All rights reserved.
Cerebral Asymmetry of fMRI-BOLD Responses to Visual Stimulation
Hougaard, Anders; Jensen, Bettina Hagström; Amin, Faisal Mohammad; Rostrup, Egill; Hoffmann, Michael B.; Ashina, Messoud
2015-01-01
Hemispheric asymmetry of a wide range of functions is a hallmark of the human brain. The visual system has traditionally been thought of as symmetrically distributed in the brain, but a growing body of evidence has challenged this view. Some highly specific visual tasks have been shown to depend on hemispheric specialization. However, the possible lateralization of cerebral responses to a simple checkerboard visual stimulation has not been a focus of previous studies. To investigate this, we performed two sessions of blood-oxygenation level dependent (BOLD) functional magnetic resonance imaging (fMRI) in 54 healthy subjects during stimulation with a black and white checkerboard visual stimulus. While carefully excluding possible non-physiological causes of left-to-right bias, we compared the activation of the left and the right cerebral hemispheres and related this to grey matter volume, handedness, age, gender, ocular dominance, interocular difference in visual acuity, as well as line-bisection performance. We found a general lateralization of cerebral activation towards the right hemisphere of early visual cortical areas and areas of higher-level visual processing, involved in visuospatial attention, especially in top-down (i.e., goal-oriented) attentional processing. This right hemisphere lateralization was partly, but not completely, explained by an increased grey matter volume in the right hemisphere of the early visual areas. Difference in activation of the superior parietal lobule was correlated with subject age, suggesting a shift towards the left hemisphere with increasing age. Our findings suggest a right-hemispheric dominance of these areas, which could lend support to the generally observed leftward visual attentional bias and to the left hemifield advantage for some visual perception tasks. PMID:25985078
Factors to Consider When Implementing Automated Software Testing
2016-11-10
programming, e.g., Java or Visual Basic. Subject Matter Experts (SME) with firm grasp of application being automated. 2. Additional costs for setup (e.g...Abilities (KSA) required (e.g., Test and Evaluation). 2. Analyze programming skills needed (e.g., Java , C, C++, Visual Basic). 3. Compose team – testers
Assertiveness by Older Adults with Visual Impairment: Context Matters
ERIC Educational Resources Information Center
Ryan, Ellen Bouchard; Anas, Ann P.; Mays, Heather
2008-01-01
Within a communication predicament of aging and disability framework, this study examined the impact of two types of contextual variation on perceptions of older adult assertiveness within problematic service encounters. Young (N = 66) and older (N = 66) participants evaluated conversational scenarios in which a visually-impaired older woman…
Progressive Multifocal Leukoencephalopathy: Recent Advances and a Neuro-Ophthalmological Review.
Sudhakar, Padmaja; Bachman, David M; Mark, Alexander S; Berger, Joseph R; Kedar, Sachin
2015-09-01
Progressive multifocal leukoencephalopathy (PML) is a severe often fatal opportunistic infection of the central nervous system caused by reactivation of a ubiquitous polyoma virus, JC virus. Although typically characterized by multifocal asymmetric subcortical white matter lesions, it may be monofocal and affect the cortical gray matter. Among the broad spectrum of clinical manifestations that occurs with PML, visual complaints are common. Combination of representative personally observed cases of PML and comprehensive review of case series of PML from 1958 through 2014. Neuro-ophthalmic signs and symptoms were reported in approximately 20%-50% of patients with PML and can be the presenting manifestation in half of these. A majority of these presentations occur from damage to cerebral visual pathways resulting in visual field defects, cortical blindness, and other disorders of visual association. Given the decreased frequency of infratentorial and cerebellar involvement, ocular motility disorders are less common. Visual complaints occur in patients with PML and are often the presenting sign. Awareness of this condition is helpful in avoiding unnecessary delays in the diagnosis of PML and management of the underlying condition. Recent guidelines have established criteria for diagnosis of PML in the high-risk patient population and strategies to mitigate the risk in these populations.
Cortical Gray and Adjacent White Matter Demonstrate Synchronous Maturation in Very Preterm Infants.
Smyser, Tara A; Smyser, Christopher D; Rogers, Cynthia E; Gillespie, Sarah K; Inder, Terrie E; Neil, Jeffrey J
2016-08-01
Spatial and functional gradients of development have been described for the maturation of cerebral gray and white matter using histological and radiological approaches. We evaluated these patterns in very preterm (VPT) infants using diffusion tensor imaging. Data were obtained from 3 groups: 1) 22 VPT infants without white matter injury (WMI), of whom all had serial MRI studies during the neonatal period, 2) 19 VPT infants with WMI, of whom 3 had serial MRI studies and 3) 12 healthy, term-born infants. Regions of interest were placed in the cortical gray and adjacent white matter in primary motor, primary visual, visual association, and prefrontal regions. From the MRI data at term-equivalent postmenstrual age, differences in mean diffusivity were found in all areas between VPT infants with WMI and the other 2 groups. In contrast, minimal differences in fractional anisotropy were found between the 3 groups. These findings suggest that cortical maturation is delayed in VPT infants with WMI when compared with term control infants and VPT infants without WMI. From the serial MRI data from VPT infants, synchronous development between gray and white matter was evident in all areas and all groups, with maturation in primary motor and sensory regions preceding that of association areas. This finding highlights the regionally varying but locally synchronous nature of the development of cortical gray matter and its adjacent white matter. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.
Golgi and Ranvier: from the black reaction to a theory of referred pain
Cani, Valentina; Mazzarello, Paolo
2015-01-01
Summary In his brief report on the structure of the gray matter of the central nervous system (1873), in which he described the “black reaction”, Golgi noted the ramifications of the axon. This discovery prompted the French histologist Louis Antoine Ranvier, one of the first to try the black reaction outside Italy, to propose an ingenious theory of referred pain in his Traité technique d’histologie. Ranvier suggested that the nerve fibers originating from the irritated area and those coming from the region to which the sensation is referred converge on the same axon and thus the same cell body, causing the spatial dislocation of sensation. This theory of referred pain is a powerful example of the extraordinary clinical-physiological impact of the first of Golgi’s neurocytological discoveries. PMID:26214031
Pore size matters for potassium channel conductance
Moldenhauer, Hans; Pincuntureo, Matías
2016-01-01
Ion channels are membrane proteins that mediate efficient ion transport across the hydrophobic core of cell membranes, an unlikely process in their absence. K+ channels discriminate K+ over cations with similar radii with extraordinary selectivity and display a wide diversity of ion transport rates, covering differences of two orders of magnitude in unitary conductance. The pore domains of large- and small-conductance K+ channels share a general architectural design comprising a conserved narrow selectivity filter, which forms intimate interactions with permeant ions, flanked by two wider vestibules toward the internal and external openings. In large-conductance K+ channels, the inner vestibule is wide, whereas in small-conductance channels it is narrow. Here we raise the idea that the physical dimensions of the hydrophobic internal vestibule limit ion transport in K+ channels, accounting for their diversity in unitary conductance. PMID:27619418
Servicing Mission 4 and the Extraordinary Science of the Hubble Space Telescope
NASA Technical Reports Server (NTRS)
Wiseman, Jennifer J.
2012-01-01
Just two years ago, NASA astronauts performed a challenging and flawless final Space Shuttle servicing mission to the orbiting Hubble Space Telescope. With science instruments repaired on board and two new ones installed, the observatory. is more powerful now than ever before. I will show the dramatic highlights of the servicing mission and present some of the early scientific results from the refurbished telescope. Its high sensitivity and multi-wavelength capabilities are revealing the highest redshift galaxies ever seen, as well as details of the cosmic web of intergalactic medium, large scale structure formation, solar system bodies, and stellar evolution. Enlightening studies of dark matter, dark energy, and exoplanet atmospheres add to the profound contributions to astrophysics that are being made with Hubble, setting a critical stage for future observatories such as the James Webb Space Telescope.
Chirality dependent interaction of ammonia with carbon nanotubes
NASA Astrophysics Data System (ADS)
Talukdar, Keka; Shantappa, Anil
2018-04-01
For the specific structure and extraordinary properties, carbon nanotubes (CNTs) have many applications in diversified fields. The interaction of CNTs with ammonia is a very interesting matter to study as it is related to the application of CNTs as ammonia sensor. Here the interaction of single walled zigzag, armchair and chiral carbon nanotubes is studied in respect of the change in energies before and after binding with ammonia by molecular dynamics simulation. Their deformation after simulation is modeled. The change of thermal conductivity of the CNTs is also found by simulation. The potential energy before and after absorption of ammonia gives useful information of the system. Thermal conductivities of the ammonia bound CNTs are changed considerably. It is observed that the potential energy and thermal conductivity both are changing for the interaction with ammonia and hence they are sensitive to ammonia binding.
Drawing on the right side of the brain: a voxel-based morphometry analysis of observational drawing.
Chamberlain, Rebecca; McManus, I Chris; Brunswick, Nicola; Rankin, Qona; Riley, Howard; Kanai, Ryota
2014-08-01
Structural brain differences in relation to expertise have been demonstrated in a number of domains including visual perception, spatial navigation, complex motor skills and musical ability. However no studies have assessed the structural differences associated with representational skills in visual art. As training artists are inclined to be a heterogeneous group in terms of their subject matter and chosen media, it was of interest to investigate whether there would be any consistent changes in neural structure in response to increasing representational drawing skill. In the current study a cohort of 44 graduate and post-graduate art students and non-art students completed drawing tasks. Scores on these tasks were then correlated with the regional grey and white matter volume in cortical and subcortical structures. An increase in grey matter density in the left anterior cerebellum and the right medial frontal gyrus was observed in relation to observational drawing ability, whereas artistic training (art students vs. non-art students) was correlated with increased grey matter density in the right precuneus. This suggests that observational drawing ability relates to changes in structures pertaining to fine motor control and procedural memory, and that artistic training in addition is associated with enhancement of structures pertaining to visual imagery. The findings corroborate the findings of small-scale fMRI studies and provide insights into the properties of the developing artistic brain. Copyright © 2014 Elsevier Inc. All rights reserved.
Landscape by Moonlight: Peter Paul Rubens and Astronomy
NASA Astrophysics Data System (ADS)
Mendillo, M.
2016-01-01
In the last years of his life, Rubens (1577-1640) lived happily with his wife and children on his Het Steen estate. During this period he worked and reworked a painting that had special meaning to him—Landscape by Moonlight (1635-40), now at the Courtauld Gallery in London. After a highly successful career painting religious and secular portraits, allegories, and occasional landscapes, Rubens put an extraordinary amount of effort into this final landscape. He was well known as a person who would commit to memory ideas and themes that he would use in future works. This paper reviews Rubens' attention to the visualization of nature, his personal connections to Elsheimer, Galileo, and Peiresc, and explores his possible depiction of constellations recalled from memory and placed within the cloudy skies in his Landscape by Moonlight.
Ho, Leon C.; Wang, Bo; Conner, Ian P.; van der Merwe, Yolandi; Bilonick, Richard A.; Kim, Seong-Gi; Wu, Ed X.; Sigal, Ian A.; Wollstein, Gadi; Schuman, Joel S.; Chan, Kevin C.
2015-01-01
Purpose. Excitotoxicity has been linked to the pathogenesis of ocular diseases and injuries and may involve early degeneration of both anterior and posterior visual pathways. However, their spatiotemporal relationships remain unclear. We hypothesized that the effects of excitotoxic retinal injury (ERI) on the visual system can be revealed in vivo by diffusion tensor magnetic resonance imagining (DTI), manganese-enhanced magnetic resonance imagining (MRI), and optical coherence tomography (OCT). Methods. Diffusion tensor MRI was performed at 9.4 Tesla to monitor white matter integrity changes after unilateral N-methyl-D-aspartate (NMDA)-induced ERI in six Sprague-Dawley rats and six C57BL/6J mice. Additionally, four rats and four mice were intravitreally injected with saline to compare with NMDA-injected animals. Optical coherence tomography of the retina and manganese-enhanced MRI of anterograde transport were evaluated and correlated with DTI parameters. Results. In the rat optic nerve, the largest axial diffusivity decrease and radial diffusivity increase occurred within the first 3 and 7 days post ERI, respectively, suggestive of early axonal degeneration and delayed demyelination. The optic tract showed smaller directional diffusivity changes and weaker DTI correlations with retinal thickness compared with optic nerve, indicative of anterograde degeneration. The splenium of corpus callosum was also reorganized at 4 weeks post ERI. The DTI profiles appeared comparable between rat and mouse models. Furthermore, the NMDA-injured visual pathway showed reduced anterograde manganese transport, which correlated with diffusivity changes along but not perpendicular to optic nerve. Conclusions. Diffusion tensor MRI, manganese-enhanced MRI, and OCT provided an in vivo model system for characterizing the spatiotemporal changes in white matter integrity, the eye–brain relationships and structural–physiological relationships in the visual system after ERI. PMID:26066747
Brain white matter microstructure is associated with susceptibility to motion-induced nausea.
Napadow, V; Sheehan, J; Kim, J; Dassatti, A; Thurler, A H; Surjanhata, B; Vangel, M; Makris, N; Schaechter, J D; Kuo, B
2013-05-01
Nausea is associated with significant morbidity, and there is a wide range in the propensity of individuals to experience nausea. The neural basis of the heterogeneity in nausea susceptibility is poorly understood. Our previous functional magnetic resonance imaging (fMRI) study in healthy adults showed that a visual motion stimulus caused activation in the right MT+/V5 area, and that increased sensation of nausea due to this stimulus was associated with increased activation in the right anterior insula. For the current study, we hypothesized that individual differences in visual motion-induced nausea are due to microstructural differences in the inferior fronto-occipital fasciculus (IFOF), the white matter tract connecting the right visual motion processing area (MT+/V5) and right anterior insula. To test this hypothesis, we acquired diffusion tensor imaging data from 30 healthy adults who were subsequently dichotomized into high and low nausea susceptibility groups based on the Motion Sickness Susceptibility Scale. We quantified diffusion along the IFOF for each subject based on axial diffusivity (AD); radial diffusivity (RD), mean diffusivity (MD) and fractional anisotropy (FA), and evaluated between-group differences in these diffusion metrics. Subjects with high susceptibility to nausea rated significantly (P < 0.001) higher nausea intensity to visual motion stimuli and had significantly (P < 0.05) lower AD and MD along the right IFOF compared to subjects with low susceptibility to nausea. This result suggests that differences in white matter microstructure within tracts connecting visual motion and nausea-processing brain areas may contribute to nausea susceptibility or may have resulted from an increased history of nausea episodes. © 2013 Blackwell Publishing Ltd.
The Film as Visual Aided Learning Tool in Classroom Management Course
ERIC Educational Resources Information Center
Altinay Gazi, Zehra; Altinay Aksal, Fahriye
2011-01-01
This research aims to investigate the impact of the visual aided learning on pre-service teachers' co-construction of subject matter knowledge in teaching practice. The study revealed the examination of film as an active cognizing and learning tool in classroom management course within teacher education programme. Within the framework of action…
PLANETarium Pilot: visualizing PLANET Earth inside-out on the planetarium's full-dome
NASA Astrophysics Data System (ADS)
Ballmer, Maxim; Wiethoff, Tobias
2016-04-01
In the past decade, projection systems in most planetariums, traditional sites of outreach and education, have advanced from interfaces that can display the motion of stars as moving beam spots to systems that are able to visualize multicolor, high-resolution, immersive full-dome videos or images. These extraordinary capabilities are ideally suited for visualization of global processes occurring on the surface and within the interior of the Earth, a spherical body just as the full dome. So far, however, our community has largely ignored this wonderful interface for outreach and education, and any previous geo-shows have mostly been limited to cartoon-style animations. Thus, we here propose a framework to convey recent scientific results on the origin and evolution of our PLANET to the >100 million per-year worldwide audience of planetariums, making the traditionally astronomy-focussed interface a true PLANETarium. In order to do this most efficiently, we intend to show "inside-out" visualizations of scientific datasets and models, as if the audience was positioned in the Earth's core. Such visualizations are expected to be renderable to the dome with little or no effort. For example, showing global geophysical datasets (e.g., gravity, air temperature), or horizontal slices of seismic-tomography images and spherical computer models requires no rendering at all. Rendering of 3D Cartesian datasets or models may further be achieved using standard techiques. Here, we show several example pilot animations. These animations rendered for the full dome are projected back to 2D for visualization on the flatscreen. Present-day science visualizations are typically as intuitive as cartoon-style animations, yet more appealing visually, and clearly with a higher level of detail. In addition to e.g. climate change and natural hazards, themes for any future geo-shows may include the coupled evolution of the Earth's interior and life, from the accretion of our planet to the evolution of mantle convection as well as the sustainment of a magnetic field and habitable conditions. We believe that high-quality tax-funded science visualizations should not exclusively be used for communication among scientists, but also recycled to raise the public's awareness and appreciation of the Geosciences.
PLANETarium Pilot: visualizing PLANET Earth inside-out on the planetarium's full-dome
NASA Astrophysics Data System (ADS)
Ballmer, M. D.; Wiethoff, T.
2014-12-01
In the past decade, projection systems in most planetariums, traditional sites of outreach and education, have advanced from interfaces that can display the motion of stars as moving beam spots to systems that are able to visualize multicolor, high-resolution, immersive full-dome videos or images. These extraordinary capabilities are ideally suited for visualization of global processes occurring on the surface and within the interior of the Earth, a spherical body just as the full dome. So far, however, our community has largely ignored this wonderful interface for outreach and education, and any previous geo-shows have mostly been limited to cartoon-style animations. Thus, we here propose a framework to convey recent scientific results on the origin and evolution of our PLANET to the >100 million per-year worldwide audience of planetariums, making the traditionally astronomy-focussed interface a true PLANETarium. In order to do this most efficiently, we intend to show „inside-out" visualizations of scientific datasets and models, as if the audience was positioned in the Earth's inner core. Such visualizations are expected to be renderable to the dome with little or no effort. For example, showing global geophysical datasets (e.g., gravity, air temperature), or horizontal slices of seismic-tomography images and spherical computer models requires no rendering at all. Rendering of 3D Cartesian datasets or models may further be achieved using standard techiques. Here, we show several example pilot animations. These animations rendered for the full dome are projected back to 2D for visualization on a flatscreen. Present-day science visualizations are typically as intuitive as cartoon-style animations, yet more appealing visually, and clearly with a higher level of detail. In addition to e.g. climate change and natural hazards, themes for any future geo-shows may include the coupled evolution of the Earth's interior and life, from the accretion of our planet to the evolution of mantle convection as well as the sustainment of a magnetic field and habitable conditions. We believe that high-quality tax-funded science visualizations should not exclusively be used for communication among scientists, but also recycled to raise the public's awareness and appreciation of the geosciences.
Diffusion fMRI detects white-matter dysfunction in mice with acute optic neuritis
Lin, Tsen-Hsuan; Spees, William M.; Chiang, Chia-Wen; Trinkaus, Kathryn; Cross, Anne H.; Song, Sheng-Kwei
2014-01-01
Optic neuritis is a frequent and early symptom of multiple sclerosis (MS). Conventional magnetic resonance (MR) techniques provide means to assess multiple MS-related pathologies, including axonal injury, demyelination, and inflammation. A method to directly and non-invasively probe white-matter function could further elucidate the interplay of underlying pathologies and functional impairments. Previously, we demonstrated a significant 27% activation-associated decrease in the apparent diffusion coefficient of water perpendicular to the axonal fibers (ADC⊥) in normal C57BL/6 mouse optic nerve with visual stimulation using diffusion fMRI. Here we apply this approach to explore the relationship between visual acuity, optic nerve pathology, and diffusion fMRI in the experimental autoimmune encephalomyelitis (EAE) mouse model of optic neuritis. Visual stimulation produced a significant 25% (vs. baseline) ADC⊥ decrease in sham EAE optic nerves, while only a 7% (vs. baseline) ADC⊥ decrease was seen in EAE mice with acute optic neuritis. The reduced activation-associated ADC⊥ response correlated with post-MRI immunohistochemistry determined pathologies (including inflammation, demyelination, and axonal injury). The negative correlation between activation-associated ADC⊥ response and visual acuity was also found when pooling EAE-affected and sham groups under our experimental criteria. Results suggest that reduction in diffusion fMRI directly reflects impaired axonal-activation in EAE mice with optic neuritis. Diffusion fMRI holds promise for directly gauging in vivo white-matter dysfunction or therapeutic responses in MS patients. PMID:24632420
Visualization of expanding warm dense gold and diamond heated rapidly by laser-generated ion beams
Bang, W.; Albright, B. J.; Bradley, P. A.; ...
2015-09-22
With the development of several novel heating sources, scientists can now heat a small sample isochorically above 10,000 K. Although matter at such an extreme state, known as warm dense matter, is commonly found in astrophysics (e.g., in planetary cores) as well as in high energy density physics experiments, its properties are not well understood and are difficult to predict theoretically. This is because the approximations made to describe condensed matter or high-temperature plasmas are invalid in this intermediate regime. A sufficiently large warm dense matter sample that is uniformly heated would be ideal for these studies, but has beenmore » unavailable to date. We have used a beam of quasi-monoenergetic aluminum ions to heat gold and diamond foils uniformly and isochorically. For the first time, we visualized directly the expanding warm dense gold and diamond with an optical streak camera. Furthermore, we present a new technique to determine the initial temperature of these heated samples from the measured expansion speeds of gold and diamond into vacuum. We anticipate the uniformly heated solid density target will allow for direct quantitative measurements of equation-of-state, conductivity, opacity, and stopping power of warm dense matter, benefiting plasma physics, astrophysics, and nuclear physics.« less
Visualization of expanding warm dense gold and diamond heated rapidly by laser-generated ion beams.
Bang, W; Albright, B J; Bradley, P A; Gautier, D C; Palaniyappan, S; Vold, E L; Santiago Cordoba, M A; Hamilton, C E; Fernández, J C
2015-09-22
With the development of several novel heating sources, scientists can now heat a small sample isochorically above 10,000 K. Although matter at such an extreme state, known as warm dense matter, is commonly found in astrophysics (e.g., in planetary cores) as well as in high energy density physics experiments, its properties are not well understood and are difficult to predict theoretically. This is because the approximations made to describe condensed matter or high-temperature plasmas are invalid in this intermediate regime. A sufficiently large warm dense matter sample that is uniformly heated would be ideal for these studies, but has been unavailable to date. Here we have used a beam of quasi-monoenergetic aluminum ions to heat gold and diamond foils uniformly and isochorically. For the first time, we visualized directly the expanding warm dense gold and diamond with an optical streak camera. Furthermore, we present a new technique to determine the initial temperature of these heated samples from the measured expansion speeds of gold and diamond into vacuum. We anticipate the uniformly heated solid density target will allow for direct quantitative measurements of equation-of-state, conductivity, opacity, and stopping power of warm dense matter, benefiting plasma physics, astrophysics, and nuclear physics.
Visualization of expanding warm dense gold and diamond heated rapidly by laser-generated ion beams
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bang, W.; Albright, B. J.; Bradley, P. A.
With the development of several novel heating sources, scientists can now heat a small sample isochorically above 10,000 K. Although matter at such an extreme state, known as warm dense matter, is commonly found in astrophysics (e.g., in planetary cores) as well as in high energy density physics experiments, its properties are not well understood and are difficult to predict theoretically. This is because the approximations made to describe condensed matter or high-temperature plasmas are invalid in this intermediate regime. A sufficiently large warm dense matter sample that is uniformly heated would be ideal for these studies, but has beenmore » unavailable to date. We have used a beam of quasi-monoenergetic aluminum ions to heat gold and diamond foils uniformly and isochorically. For the first time, we visualized directly the expanding warm dense gold and diamond with an optical streak camera. Furthermore, we present a new technique to determine the initial temperature of these heated samples from the measured expansion speeds of gold and diamond into vacuum. We anticipate the uniformly heated solid density target will allow for direct quantitative measurements of equation-of-state, conductivity, opacity, and stopping power of warm dense matter, benefiting plasma physics, astrophysics, and nuclear physics.« less
Visualization of expanding warm dense gold and diamond heated rapidly by laser-generated ion beams
NASA Astrophysics Data System (ADS)
Bang, W.; Albright, B. J.; Bradley, P. A.; Gautier, D. C.; Palaniyappan, S.; Vold, E. L.; Cordoba, M. A. Santiago; Hamilton, C. E.; Fernández, J. C.
2015-09-01
With the development of several novel heating sources, scientists can now heat a small sample isochorically above 10,000 K. Although matter at such an extreme state, known as warm dense matter, is commonly found in astrophysics (e.g., in planetary cores) as well as in high energy density physics experiments, its properties are not well understood and are difficult to predict theoretically. This is because the approximations made to describe condensed matter or high-temperature plasmas are invalid in this intermediate regime. A sufficiently large warm dense matter sample that is uniformly heated would be ideal for these studies, but has been unavailable to date. Here we have used a beam of quasi-monoenergetic aluminum ions to heat gold and diamond foils uniformly and isochorically. For the first time, we visualized directly the expanding warm dense gold and diamond with an optical streak camera. Furthermore, we present a new technique to determine the initial temperature of these heated samples from the measured expansion speeds of gold and diamond into vacuum. We anticipate the uniformly heated solid density target will allow for direct quantitative measurements of equation-of-state, conductivity, opacity, and stopping power of warm dense matter, benefiting plasma physics, astrophysics, and nuclear physics.
48 CFR 750.7103 - Definitions.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Definitions. 750.7103 Section 750.7103 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions To Protect Foreign Policy...
48 CFR 750.7105 - Approving authorities.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Approving authorities. 750.7105 Section 750.7105 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions To Protect Foreign...
48 CFR 750.7108 - Contractual requirements.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contractual requirements. 750.7108 Section 750.7108 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions To Protect Foreign...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-12-15
... Change To Extend Pilot Program Related to Trading Pauses Due to Extraordinary Market Volatility December... Halts Due to Extraordinary Market Volatility.'' The Exchange proposes to extend the pilot program...
Resurrecting hot dark matter - Large-scale structure from cosmic strings and massive neutrinos
NASA Technical Reports Server (NTRS)
Scherrer, Robert J.
1988-01-01
These are the results of a numerical simulation of the formation of large-scale structure from cosmic-string loops in a universe dominated by massive neutrinos (hot dark matter). This model has several desirable features. The final matter distribution contains isolated density peaks embedded in a smooth background, producing a natural bias in the distribution of luminous matter. Because baryons can accrete onto the cosmic strings before the neutrinos, the galaxies will have baryon cores and dark neutrino halos. Galaxy formation in this model begins much earlier than in random-phase models. On large scales the distribution of clustered matter visually resembles the CfA survey, with large voids and filaments.
ERIC Educational Resources Information Center
Cherif, Abour A.; Adams, Gerald E.; Cannon, Charles E.
1997-01-01
Describes several activities used to teach students from middle school age to college nonmajors about the nature of matter, atoms, molecules and the periodic table. Strategies integrate such approaches as hands-on activities, visualization, writing, demonstrations, role play, and guided inquiry. For example, the periodic table is viewed as a town…
NASA Astrophysics Data System (ADS)
Tapia, E. M.; Minjarez, J. I.; Espinoza, I. G.; Sosa, C. M.
2013-05-01
Climate change in Northwestern Mexico and its hydrological impact on water balance, water scarcity and flooding events, has become a matter of increasing concern over the past several decades due to the region's semiarid conditions. Changes in temperature, precipitation, and sea level will affect agriculture, farming, and aquaculture, in addition to compromising the quality of water resources for human consumption. According to the Fourth Assessment Report of the Intergovernmental Panel on Climate Change (IPCC, 2007), Global Circulation Models (GCMs) can provide reliable estimations of future climate conditions in addition to atmospheric processes that cause them, based on different input scenarios such as A2 (higher emission of greenhouse gases) and B1 (lower emission of GHG), among others. However, GCM`s resolution results to coarse in regions which have high space and time climate variability. To remediate this, several methods based on dynamical, statistical and empirical analysis have been proposed for downcaling. In this study, we evaluate possible changes in precipitation and temperature for the "Rio Yaqui Basin" in Sonora, Mexico and assess the impact of such changes on runoff, evapotranspiration and aquifer recharge for the 2010-2099 period of time. For this purpose, we analyzed the results of a Bias Corrected and Downscaled Climate Projection from the World Climate Research Programme's (WCRP's) Coupled Model Intercomparison Project phase 3 (CMIP3) multi-model dataset: UKMO-HADCM3 from the Hadley Centre for Climate Prediction. Northwest Mexico is under the influence of the North American Monsoon (NAM), a system affecting the states of Sinaloa and Sonora where the precipitation regimes change drastically during the summer months of June, July and August. It is associated to the sharp variations of topography, precipitation and temperature regimes in the region, so the importance of analyzing the downscaled climate projections. The Rio Yaqui Basin is one of the most important basins in Sonora. It is located in northwestern Mexico, and covers an approximate area of 74,054 km2, providing water for one of the most prominent agricultural zones in the state. We used the System Thinking Software "Stella 9.0.2" to dynamically visualize the effects of climate change on the Rio Yaqui Basin. In this software, the main components of the water balance are simulated over the designated period of time with tools that include stocks and flow diagrams, causal loops, model equations and built in functions. Climate change projections for the Rio Yaqui Basin showed highly variable runoff behaviors, indicating the possibility of frequent droughts alternating with years of extraordinary runoff. Simulations generated through the System Thinking Software provides a reasonable basis for establishing policies for optimizing storage of water during extraordinary runoff periods that can serve as water supplies during frequent droughts.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Mistakes. 750.7106-3 Section 750.7106-3 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions To Protect Foreign Policy...
48 CFR 750.7110 - Processing cases.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Processing cases. 750.7110 Section 750.7110 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions To Protect Foreign Policy...
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false General. 750.7106-1 Section 750.7106-1 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions To Protect Foreign Policy...
48 CFR 750.7102 - General policy.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false General policy. 750.7102 Section 750.7102 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions To Protect Foreign Policy...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-01-25
... Change To Extend Pilot Program Related to Trading Pauses Due to Extraordinary Market Volatility January... Halts Due to Extraordinary Market Volatility.'' The text of the proposed rule change is available at the...
Increased integrity of white matter pathways after dual n-back training.
Salminen, Tiina; Mårtensson, Johan; Schubert, Torsten; Kühn, Simone
2016-06-01
Dual n-back WM training has been shown to produce broad transfer effects to different untrained cognitive functions. The task is demanding to the cognitive system because it includes a bi-modal (auditory and visual) dual-task component. A previous WM training study showed increased white matter integrity in the parietal lobe as well as the anterior part of the corpus callosum after visual n-back training. We investigated dual n-back training-related changes in white matter pathways. We anticipated dual n-back training to increase white matter integrity in pathways that connect brain regions related to WM processes. Additionally, we hypothesized that dual n-back training would produce more brain-wide white matter changes than single n-back training because of the involvement of two modalities and the additional dual-task coordination component of the task. The dual n-back training group showed increased white matter integrity (reflected as increased fractional anisotropy, FA) after training. The effects were mostly left lateralized as compared with changes from pretest to posttest in the passive and active control groups. Additionally, significant effects were observed in the anterior part of the corpus callosum, when the training group was compared with the passive control group. There were no changes in pretest to posttest FA changes between the passive and active control groups. The results therefore show that dual n-back training produces increased integrity in white matter pathways connecting different brain regions. The results are discussed in reference to the bi-modal dual-task component of the training task. Copyright © 2016 Elsevier Inc. All rights reserved.
The visual system of diurnal raptors: updated review.
González-Martín-Moro, J; Hernández-Verdejo, J L; Clement-Corral, A
2017-05-01
Diurnal birds of prey (raptors) are considered the group of animals with highest visual acuity (VA). The purpose of this work is to review all the information recently published about the visual system of this group of animals. A bibliographic search was performed in PubMed. The algorithm used was (raptor OR falcon OR kestrel OR hawk OR eagle) AND (vision OR «visual acuity» OR eye OR macula OR retina OR fovea OR «nictitating membrane» OR «chromatic vision» OR ultraviolet). The search was restricted to the «Title» and «Abstract» fields, and to non-human species, without time restriction. The proposed algorithm located 97 articles. Birds of prey are endowed with the highest VA of the animal kingdom. However most of the works study one individual or a small group of individuals, and the methodology is heterogeneous. The most studied bird is the Peregrine falcon (Falco peregrinus), with an estimated VA of 140 cycles/degree. Some eagles are endowed with similar VA. The tubular shape of the eye, the large pupil, and a high density of photoreceptors make this extraordinary VA possible. In some species, histology and optic coherence tomography demonstrate the presence of 2foveas. The nasal fovea (deep fovea) has higher VA. Nevertheless, the exact function of each fovea is unknown. The vitreous contained in the deep fovea could behave as a third lens, adding some magnification to the optic system. Copyright © 2017 Sociedad Española de Oftalmología. Publicado por Elsevier España, S.L.U. All rights reserved.
Autistic savants. [correction of artistic].
Hou, C; Miller, B L; Cummings, J L; Goldberg, M; Mychack, P; Bottino, V; Benson, D F
2000-01-01
The objectives of this study were to examine common patterns in the lives and artwork of five artistic savants previously described and to report on the clinical, neuropsychological, and neuroimaging findings from one newly diagnosed artistic savant. The artistic savant syndrome has been recognized for centuries, although its neuroanatomic basis remains a mystery. The cardinal features, strengths, and weaknesses of the work of these six savants were analyzed and compared with those of children with autism in whom artistic talent was absent. An anatomic substrate for these behaviors was considered in the context of newly emerging theories related to paradoxical functional facilitation, visual thinking, and multiple intelligences. The artists had features of "pervasive developmental disorder," including impairment in social interaction and communication as well as restricted repetitive and stereotyped patterns of behavior, interest, and activities. All six demonstrated a strong preference for a single art medium and showed a restricted variation in artistic themes. None understood art theory. Some autistic features contributed to their success, including attention to visual detail, a tendency toward ritualistic compulsive repetition, the ability to focus on one topic at the expense of other interests, and intact memory and visuospatial skills. The artistic savant syndrome remains rare and mysterious in origin. Savants exhibit extraordinary visual talents along with profound linguistic and social impairment. The intense focus on and ability to remember visual detail contributes to the artistic product of the savant. The anatomic substrate for the savant syndrome may involve loss of function in the left temporal lobe with enhanced function of the posterior neocortex.
Imaging anatomy of the vestibular and visual systems.
Gunny, Roxana; Yousry, Tarek A
2007-02-01
This review will outline the imaging anatomy of the vestibular and visual pathways, using computed tomography and magnetic resonance imaging, with emphasis on the more recent developments in neuroimaging. Technical advances in computed tomography and magnetic resonance imaging, such as the advent of multislice computed tomography and newer magnetic resonance imaging techniques such as T2-weighted magnetic resonance cisternography, have improved the imaging of the vestibular and visual pathways, allowing better visualization of the end organs and peripheral nerves. Higher field strength magnetic resonance imaging is a promising tool, which has been used to evaluate and resolve fine anatomic detail in vitro, as in the labyrinth. Advanced magnetic resonance imaging techniques such as functional magnetic resonance imaging and diffusion tractography have been used to identify cortical areas of activation and associated white matter pathways, and show potential for the future identification of complex neuronal relays involved in integrating these pathways. The assessment of the various components of the vestibular and the visual systems has improved with more detailed research on the imaging anatomy of these systems, the advent of high field magnetic resonance scanners and multislice computerized tomography, and the wider use of specific techniques such as tractography which displays white matter tracts not directly accessible until now.
Visual Aid to Demonstrate Change of State and Gas Pressure with Temperature
ERIC Educational Resources Information Center
Ghaffari, Shahrokh
2011-01-01
Demonstrations are used in chemistry lectures to improve conceptual understanding by direct observation. The visual aid described here is designed to demonstrate the change in state of matter with the change of temperature and the change of pressure with temperature. Temperature is presented by the rate of airflow and pressure is presented by…
ERIC Educational Resources Information Center
Ryoo, Kihyun; Bedell, Kristin
2017-01-01
Although extensive research has shown the educational value of different types of interactive visualizations on students' science learning in general, how such technologies can contribute to English learners' (ELs) understanding of complex scientific concepts has not been sufficiently explored to date. This mixed-methods study investigated how…
40 CFR 52.2479 - Contents of the federally approved, State submitted implementation plan.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Perchloroethylene dry cleaning systems [02/19/91] 173-490-204 Graphic arts systems [02/19/91] 173-490-205 Surface...] 450 Emission Standards—Forward [04/14/93] 451 Emission of Air Contaminant—Visual Standards [10/13/94] 452 Motor Vehicle Visual Standard [04/14/93, except section .5] 455 Emission of Particulate Matter [04...
Efficiency of Lexical Access in Children with Autism Spectrum Disorders: Does Modality Matter?
ERIC Educational Resources Information Center
Harper-Hill, Keely; Copland, David; Arnott, Wendy
2014-01-01
The provision of visual support to individuals with an autism spectrum disorder (ASD) is widely recommended. We explored one mechanism underlying the use of visual supports: efficiency of language processing. Two groups of children, one with and one without an ASD, participated. The groups had comparable oral and written language skills and…
48 CFR 750.7100 - Scope of subpart.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Scope of subpart. 750.7100 Section 750.7100 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions To Protect Foreign Policy...
48 CFR 750.7100 - Scope of subpart.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Scope of subpart. 750.7100 Section 750.7100 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions To Protect Foreign Policy...
48 CFR 750.7100 - Scope of subpart.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Scope of subpart. 750.7100 Section 750.7100 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions To Protect Foreign Policy...
48 CFR 750.7104 - Types of actions.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Types of actions. 750.7104 Section 750.7104 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions To Protect Foreign Policy...
48 CFR 750.7109-1 - Filing requests.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Filing requests. 750.7109-1 Section 750.7109-1 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions To Protect Foreign...
48 CFR 750.7106-2 - Amendments without consideration.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Amendments without consideration. 750.7106-2 Section 750.7106-2 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions To Protect...
48 CFR 750.7106 - Standards for deciding cases.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Standards for deciding cases. 750.7106 Section 750.7106 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions To Protect...
48 CFR 750.7106-4 - Informal commitments.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Informal commitments. 750.7106-4 Section 750.7106-4 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions To Protect Foreign...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-05-24
....14, Entitled ``Trading Halts Due to Extraordinary Market Volatility'' May 19, 2010. Pursuant to... Extraordinary Market Volatility.'' The text of the proposed rule change is available at the Exchange's Web site...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-05-24
....14, Entitled ``Trading Halts Due to Extraordinary Market Volatility'' May 19, 2010. Pursuant to... Extraordinary Market Volatility.'' The text of the proposed rule change is available at the Exchange's Web site...
What makes a day at work extraordinary.
Leach, Francine; Yeager, Kerry
2013-04-01
To prevent high rates of nurse burnout and staff turnover, hospitals must create environments that fulfil nurses' expectations and foster positive emotional responses to their job. To gain an understanding of what triggers positive emotional responses, a group of nurses were asked to recall an 'extraordinary day'. Their descriptions were analysed to identify these triggers and to determine whether their perceptions of what makes an extraordinary day change over time. This article discusses the results of the study and suggests that enabling nurses to describe meaningful experiences is a step toward learning what it is they value.
Visual Annual Reviews: How to Include Pupils with Learning Difficulties in their Educational Reviews
ERIC Educational Resources Information Center
Hayes, Julia
2004-01-01
The challenge for schools, following the Green Paper Every Child Matters (HM Treasury, 2003) and the Special Educational Needs Code of Practice (DfES, 2001), is to enable young people to give their views about matters affecting their lives. Whilst these recommendations are a welcome step to enable the effective inclusion of all young people,…
ERIC Educational Resources Information Center
Cross, Beth
2012-01-01
Participatory research with young people has enjoyed a decade of sustained development including the development of a range of embodied and visual methodologies. Much of this has been in the service of a participatory citizenship agenda, as articulated in the Every Child Matters agenda in England, in the work of the UK's Children's Commissioners…
Gray Matter Pathology in MS: Neuroimaging and Clinical Correlations
Honce, Justin Morris
2013-01-01
It is abundantly clear that there is extensive gray matter pathology occurring in multiple sclerosis. While attention to gray matter pathology was initially limited to studies of autopsy specimens and biopsies, the development of new MRI techniques has allowed assessment of gray matter pathology in vivo. Current MRI techniques allow the direct visualization of gray matter demyelinating lesions, the quantification of diffuse damage to normal appearing gray matter, and the direct measurement of gray matter atrophy. Gray matter demyelination (both focal and diffuse) and gray matter atrophy are found in the very earliest stages of multiple sclerosis and are progressive over time. Accumulation of gray matter damage has substantial impact on the lives of multiple sclerosis patients; a growing body of the literature demonstrates correlations between gray matter pathology and various measures of both clinical disability and cognitive impairment. The effect of disease modifying therapies on the rate accumulation of gray matter pathology in MS has been investigated. This review focuses on the neuroimaging of gray matter pathology in MS, the effect of the accumulation of gray matter pathology on clinical and cognitive disability, and the effect of disease-modifying agents on various measures of gray matter damage. PMID:23878736
48 CFR 750.7109 - Submission of requests by contractors.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Submission of requests by contractors. 750.7109 Section 750.7109 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions To Protect...
48 CFR 750.7109-3 - Facts and evidence.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Facts and evidence. 750.7109-3 Section 750.7109-3 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions To Protect Foreign...
48 CFR 1450.104 - Residual powers.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Residual powers. 1450.104 Section 1450.104 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Extraordinary Contractual Actions 1450.104 Residual powers. ...
48 CFR 1450.104 - Residual powers.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Residual powers. 1450.104 Section 1450.104 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Extraordinary Contractual Actions 1450.104 Residual powers. ...
48 CFR 1350.102-1 - Delegation of authority.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Delegation of authority. 1350.102-1 Section 1350.102-1 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions 1350.102-1 Delegation of...
Innovation and stasis: technology and race in Mark Twain's Pudd'nhead Wilson.
Current, Cynthia A
2009-01-01
Mark Twain's Pudd'nhead Wilson demonstrates how technologies of identification attempt to counter how bodies evolve beyond previous constraints—in particular, the constraints of racial classification. Twain develops accounts of subjectivity and racial classification that cover an extraordinary breadth of genealogy, biology, and law, while still invoking elements of randomness and chance. The key to such combinations of fixity and emergence in human identity is the technology of fingerprinting. Twain's speculative engagement with fingerprinting creates a system and medium to classify and secure particular forms of identity, leading to the reassertion of racial values already inherent in science and technology, law, and commerce. Fingerprinting represents the direction that technologies of identity would seek to employ: a movement away from direct visual observation of bodies, whose emergence and change over time make them difficult to categorize, to reliance on archives of information that are increasingly removed from the contexts of meaning and emergence those bodies inhabit; this reflects "one drop" politics, as race becomes increasingly difficult to define visually. The archive itself, then, becomes infected with the spectacular vitality of, and the speculation and risk within, nineteenth-century biological and cultural determinism.
Spontaneous generation in medieval Jewish philosophy and theology.
Gaziel, Ahuva
2012-01-01
The concept of life forms emerging from inanimate matter--spontaneous generation--was widely accepted until the nineteenth century. Several medieval Jewish scholars acknowledged this scientific theory in their philosophical and religious contemplations. Quite interestingly, it served to reinforce diverse, or even opposite, theological conclusions. One approach excluded spontaneously-generated living beings form the biblical account of creation or the story of the Deluge. Underlying this view is an understanding that organisms that generate spontaneously evolve continuously in nature and, therefore, do not require divine intervention in their formation or survival during disastrous events. This naturalistic position reduces the miraculous dimension of reality. Others were of the opinion that spontaneous generation is one of the extraordinary marvels exhibited in this world and, accordingly, this interpretation served to accentuate the divine aspect of nature. References to spontaneous generation also appear in legal writings, influencing practical applications such as dietary laws and actions forbidden on the Sabbath.
The Neutron Star Interior Composition Explorer (NICER)
NASA Technical Reports Server (NTRS)
Wilson-Hodge, Colleen A.; Gendreau, K.; Arzoumanian, Z.
2014-01-01
The Neutron Star Interior Composition Explorer (NICER) is an approved NASA Explorer Mission of Opportunity dedicated to the study of the extraordinary gravitational, electromagnetic, and nuclear-physics environments embodied by neutron stars. Scheduled to be launched in 2016 as an International Space Station payload, NICER will explore the exotic states of matter, using rotation-resolved spectroscopy of the thermal and non-thermal emissions of neutron stars in the soft (0.2-12 keV) X-ray band. Grazing-incidence "concentrator" optics coupled with silicon drift detectors, actively pointed for a full hemisphere of sky coverage, will provide photon-counting spectroscopy and timing registered to GPS time and position, with high throughput and relatively low background. The NICER project plans to implement a Guest Observer Program, which includes competitively selected user targets after the first year of flight operations. I will describe NICER and discuss ideas for potential Be/X-ray binary science.
An insect-like mushroom body in a crustacean brain
Wolff, Gabriella Hannah; Thoen, Hanne Halkinrud; Marshall, Justin; Sayre, Marcel E
2017-01-01
Mushroom bodies are the iconic learning and memory centers of insects. No previously described crustacean possesses a mushroom body as defined by strict morphological criteria although crustacean centers called hemiellipsoid bodies, which serve functions in sensory integration, have been viewed as evolutionarily convergent with mushroom bodies. Here, using key identifiers to characterize neural arrangements, we demonstrate insect-like mushroom bodies in stomatopod crustaceans (mantis shrimps). More than any other crustacean taxon, mantis shrimps display sophisticated behaviors relating to predation, spatial memory, and visual recognition comparable to those of insects. However, neuroanatomy-based cladistics suggesting close phylogenetic proximity of insects and stomatopod crustaceans conflicts with genomic evidence showing hexapods closely related to simple crustaceans called remipedes. We discuss whether corresponding anatomical phenotypes described here reflect the cerebral morphology of a common ancestor of Pancrustacea or an extraordinary example of convergent evolution. PMID:28949916
Ahlfors, Seppo P.; Jones, Stephanie R.; Ahveninen, Jyrki; Hämäläinen, Matti S.; Belliveau, John W.; Bar, Moshe
2014-01-01
Identifying inter-area communication in terms of the hierarchical organization of functional brain areas is of considerable interest in human neuroimaging. Previous studies have suggested that the direction of magneto- and electroencephalography (MEG, EEG) source currents depends on the layer-specific input patterns into a cortical area. We examined the direction in MEG source currents in a visual object recognition experiment in which there were specific expectations of activation in the fusiform region being driven by either feedforward or feedback inputs. The source for the early non-specific visual evoked response, presumably corresponding to feedforward driven activity, pointed outward, i.e., away from the white matter. In contrast, the source for the later, object-recognition related signals, expected to be driven by feedback inputs, pointed inward, toward the white matter. Associating specific features of the MEG/EEG source waveforms to feedforward and feedback inputs could provide unique information about the activation patterns within hierarchically organized cortical areas. PMID:25445356
48 CFR 750.7109-2 - Form of requests by contractors.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Form of requests by contractors. 750.7109-2 Section 750.7109-2 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions To Protect...
48 CFR 50.104 - Residual powers.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Residual powers. 50.104... EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Extraordinary Contractual Actions 50.104 Residual powers. This section prescribes standards and procedures for exercising residual powers under Pub. L. 85-804...
18 CFR 367.8 - Extraordinary items.
Code of Federal Regulations, 2012 CFR
2012-04-01
... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Extraordinary items. 367.8 Section 367.8 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION... are considered generally accepted accounting principles. These items are related to the effects of...
48 CFR 50.104 - Residual powers.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Residual powers. 50.104... EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Extraordinary Contractual Actions 50.104 Residual powers. This section prescribes standards and procedures for exercising residual powers under Pub. L. 85-804...
48 CFR 50.103-2 - Types of contract adjustment.
Code of Federal Regulations, 2011 CFR
2011-10-01
... contract; for example, when a person, responding to an agency official's written or oral instructions and... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Types of contract... CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Extraordinary Contractual Actions...
48 CFR 50.103-2 - Types of contract adjustment.
Code of Federal Regulations, 2010 CFR
2010-10-01
... contract; for example, when a person, responding to an agency official's written or oral instructions and... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Types of contract... CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Extraordinary Contractual Actions...
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Records. 1450.101-3... EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Extraordinary Contractual Actions 1450.101-3 Records. The records of actions taken under FAR Part 50 shall be maintained by the Director, PAM. ...
Code of Federal Regulations, 2013 CFR
2013-10-01
... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Records. 1450.101-3... EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Extraordinary Contractual Actions 1450.101-3 Records. The records of actions taken under FAR Part 50 shall be maintained by the Director, PAM. ...
Code of Federal Regulations, 2011 CFR
2011-10-01
... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Records. 1450.101-3... EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Extraordinary Contractual Actions 1450.101-3 Records. The records of actions taken under FAR Part 50 shall be maintained by the Director, PAM. ...
Code of Federal Regulations, 2014 CFR
2014-10-01
... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Records. 1450.101-3... EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Extraordinary Contractual Actions 1450.101-3 Records. The records of actions taken under FAR Part 50 shall be maintained by the Director, PAM. ...
78 FR 40665 - Cost Accounting Standards: CAS 413 Pension Adjustments for Extraordinary Events
Federal Register 2010, 2011, 2012, 2013, 2014
2013-07-08
... Accounting Standards: CAS 413 Pension Adjustments for Extraordinary Events AGENCY: Cost Accounting Standards...: The Office of Federal Procurement Policy (OFPP), Cost Accounting Standards (CAS) Board, is conducting..., Director, Cost Accounting Standards Board (telephone: 202-395-6805; email: [email protected
What are the limits of energy focusing in sonoluminescence?
NASA Astrophysics Data System (ADS)
Putterman, Seth; Camara, C.; Kappus, B.; Su, C. K.; Kirilov, E.
2003-04-01
Sonoluminescence [SL] is amazing for the extraordinary degree by which ultrasonic energy can be focused by a cavitating bubble. Local energy dissipation exceeds Kirkhoff's law by 1E15 and the acoustic energy density concentrates by 12 orders of magnitude to create picosecond flashes of broadband ultraviolet light. At the minimum bubble radius, the acceleration exceeds 1E11 g and a megabar level shock wave is emitted into the surrounding fluid. For single bubbles driven at 30 KHz, SL is nature's smallest blackbody. This implies that the bubble's interior is such a dense plasma that the photon-matter mean free path is shorter than the wavelength of light, and suggests that SL originates in an unusual state of matter. Excitation of a vertical column of fluid [~10 Hz] so as to create a water hammer leads to the upscaling of SL and generation of flashes of light with 3E8 photons and peak powers approaching 1 W. At 1 MHz, the spectrum resembles bremsstrahlung from a transparent plasma with a temperature ~1 MK. At 10 MHz the collapsed size of the SL bubble approaches 10 nm, which raises the possibility that the SL parameter space may extend to the domain of quantum mechanics. [Research supported by DARPA and DOE.
NASA Astrophysics Data System (ADS)
Pletikapić, Galja; Ivošević DeNardis, Nadica
2017-01-01
Surface analytical methods are applied to examine the environmental status of seawaters. The present overview emphasizes advantages of combining surface analytical methods, applied to a hazardous situation in the Adriatic Sea, such as monitoring of the first aggregation phases of dissolved organic matter in order to potentially predict the massive mucilage formation and testing of oil spill cleanup. Such an approach, based on fast and direct characterization of organic matter and its high-resolution visualization, sets a continuous-scale description of organic matter from micro- to nanometre scales. Electrochemical method of chronoamperometry at the dropping mercury electrode meets the requirements for monitoring purposes due to the simple and fast analysis of a large number of natural seawater samples enabling simultaneous differentiation of organic constituents. In contrast, atomic force microscopy allows direct visualization of biotic and abiotic particles and provides an insight into structural organization of marine organic matter at micro- and nanometre scales. In the future, merging data at different spatial scales, taking into account experimental input on micrometre scale, observations on metre scale and modelling on kilometre scale, will be important for developing sophisticated technological platforms for knowledge transfer, reports and maps applicable for the marine environmental protection and management of the coastal area, especially for tourism, fishery and cruiser trafficking.
A Novel Approach to Visualizing Dark Matter Simulations.
Kaehler, R; Hahn, O; Abel, T
2012-12-01
In the last decades cosmological N-body dark matter simulations have enabled ab initio studies of the formation of structure in the Universe. Gravity amplified small density fluctuations generated shortly after the Big Bang, leading to the formation of galaxies in the cosmic web. These calculations have led to a growing demand for methods to analyze time-dependent particle based simulations. Rendering methods for such N-body simulation data usually employ some kind of splatting approach via point based rendering primitives and approximate the spatial distributions of physical quantities using kernel interpolation techniques, common in SPH (Smoothed Particle Hydrodynamics)-codes. This paper proposes three GPU-assisted rendering approaches, based on a new, more accurate method to compute the physical densities of dark matter simulation data. It uses full phase-space information to generate a tetrahedral tessellation of the computational domain, with mesh vertices defined by the simulation's dark matter particle positions. Over time the mesh is deformed by gravitational forces, causing the tetrahedral cells to warp and overlap. The new methods are well suited to visualize the cosmic web. In particular they preserve caustics, regions of high density that emerge, when several streams of dark matter particles share the same location in space, indicating the formation of structures like sheets, filaments and halos. We demonstrate the superior image quality of the new approaches in a comparison with three standard rendering techniques for N-body simulation data.
ERIC Educational Resources Information Center
Eidels, Ami; Townsend, James T.; Pomerantz, James R.
2008-01-01
People are especially efficient in processing certain visual stimuli such as human faces or good configurations. It has been suggested that topology and geometry play important roles in configural perception. Visual search is one area in which configurality seems to matter. When either of 2 target features leads to a correct response and the…
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ge, Yong; Liu, Shu-sen; Yuan, Shou-qi, E-mail: Shouqiy@ujs.edu.cn
We report an extraordinary acoustic transmission through two layer annuluses made of metal cylinders in air both numerically and experimentally. The effect arises from the enhancement and reconstruction of the incident source induced by different Mie-resonance modes of the annuluses. The proposed system takes advantages of the consistency in the waveform between the input and output waves, the high amplitude amplification of output waves, and the easy adjustment of structure. More interestingly, we investigate the applications of the extraordinary acoustic transmission in the acoustic beam splitter and acoustic concentrator. Our finding should have an impact on ultrasonic applications.
Evidence for a basal temporal visual language center: cortical stimulation producing pure alexia.
Mani, J; Diehl, B; Piao, Z; Schuele, S S; Lapresto, E; Liu, P; Nair, D R; Dinner, D S; Lüders, H O
2008-11-11
Dejerine and Benson and Geschwind postulated disconnection of the dominant angular gyrus from both visual association cortices as the basis for pure alexia, emphasizing disruption of white matter tracts in the dominant temporooccipital region. Recently functional imaging studies provide evidence for direct participation of basal temporal and occipital cortices in the cognitive process of reading. The exact location and function of these areas remain a matter of debate. To confirm the participation of the basal temporal region in reading. Extraoperative electrical stimulation of the dominant hemisphere was performed in three subjects using subdural electrodes, as part of presurgical evaluation for refractory epilepsy. Pure alexia was reproduced during cortical stimulation of the dominant posterior fusiform and inferior temporal gyri in all three patients. Stimulation resulted in selective reading difficulty with intact auditory comprehension and writing. Reading difficulty involved sentences and words with intact letter by letter reading. Picture naming difficulties were also noted at some electrodes. This region is located posterior to and contiguous with the basal temporal language area (BTLA) where stimulation resulted in global language dysfunction in visual and auditory realms. The location corresponded with the visual word form area described on functional MRI. These observations support the existence of a visual language area in the dominant fusiform and occipitotemporal gyri, contiguous with basal temporal language area. A portion of visual language area was exclusively involved in lexical processing while the other part of this region processed both lexical and nonlexical symbols.
Professor Valter Rukavina (1896-1972): life between medicine and painting.
Skrobonja, Ante
2008-01-01
This article on the occasion of the 111th birthday of professor Valter Rukavina (Rijeka, 1896-1972) recalls this extraordinary personality who is remembered by local and national history as an excellent physician, infectionist, university professor, equally successful scientist and practitioner, scholar and a polyglot, art lover, and last but not least, an extraordinary self-taught painter... He graduated from secondary school in Susak and studied medicine in Innsbruck, Graz, Vienna and Prague, where he received diploma in general practice in 1921. He started his career in Zagreb, then moved to Vrbovsko, KriZevci, Osijek, and Zlatar as district physician. Meanwhile, at the Institute of Epidemiology he specialised in bacteriology, epidemiology, serology, hygiene, and medical chemistry. He successfully organised anti-typhus campaigns and mass vaccinations against scarlet fever and diphtheria, and established local healthcare stations. After a brief stay in Zagreb, in WW2 he was transferred to Bosnia, returned to Zagreb, and since 1946 until his death he had lived in his native Rijeka, where he started an infectious diseases department that later grew into the School of Medicine clinic. Being a practitioner and a scientist, he was interested in all aspects of infectious diseases and contiguous areas, and made a major contribution with his systematic research and successful implementation of preventive measures and complete eradication of the great brucellosis epidemic that broke out in Istria after WW2. In addition to the membership in a number of professional associations, professor Rukavina was also an active member of the Rijeka chapter of the Croatian Association of Visual Artists.
Cross-modal cueing of attention alters appearance and early cortical processing of visual stimuli
Störmer, Viola S.; McDonald, John J.; Hillyard, Steven A.
2009-01-01
The question of whether attention makes sensory impressions appear more intense has been a matter of debate for over a century. Recent psychophysical studies have reported that attention increases apparent contrast of visual stimuli, but the issue continues to be debated. We obtained converging neurophysiological evidence from human observers as they judged the relative contrast of visual stimuli presented to the left and right visual fields following a lateralized auditory cue. Cross-modal cueing of attention boosted the apparent contrast of the visual target in association with an enlarged neural response in the contralateral visual cortex that began within 100 ms after target onset. The magnitude of the enhanced neural response was positively correlated with perceptual reports of the cued target being higher in contrast. The results suggest that attention increases the perceived contrast of visual stimuli by boosting early sensory processing in the visual cortex. PMID:20007778
Cross-modal cueing of attention alters appearance and early cortical processing of visual stimuli.
Störmer, Viola S; McDonald, John J; Hillyard, Steven A
2009-12-29
The question of whether attention makes sensory impressions appear more intense has been a matter of debate for over a century. Recent psychophysical studies have reported that attention increases apparent contrast of visual stimuli, but the issue continues to be debated. We obtained converging neurophysiological evidence from human observers as they judged the relative contrast of visual stimuli presented to the left and right visual fields following a lateralized auditory cue. Cross-modal cueing of attention boosted the apparent contrast of the visual target in association with an enlarged neural response in the contralateral visual cortex that began within 100 ms after target onset. The magnitude of the enhanced neural response was positively correlated with perceptual reports of the cued target being higher in contrast. The results suggest that attention increases the perceived contrast of visual stimuli by boosting early sensory processing in the visual cortex.
Interactive Medical Volume Visualization for Surgical Operations
2001-10-25
the preprocessing and processing stages, related medical brain tissues, which are skull, white matter, gray matter and pathology ( tumor ), are segmented ...from 12 or 16 bit data depths. NMR segmentation plays an important role in our work, because, classifying brain tissues from NMR slices requires an...performing segmentation of brain structures. Our segmentation process uses Self Organizing Feature Maps (SOFM) [12]. In SOM, on the contrary to Feedback
Diwadkar, Vaibhav A; Bellani, Marcella; Chowdury, Asadur; Savazzi, Silvia; Perlini, Cinzia; Marinelli, Veronica; Zoccatelli, Giada; Alessandrini, Franco; Ciceri, Elisa; Rambaldelli, Gianluca; Ruggieri, Mirella; Carlo Altamura, A; Marzi, Carlo A; Brambilla, Paolo
2017-08-14
Because the visual cortices are contra-laterally organized, inter-hemispheric transfer tasks have been used to behaviorally probe how information briefly presented to one hemisphere of the visual cortex is integrated with responses resulting from the ipsi- or contra-lateral motor cortex. By forcing rapid information exchange across diverse regions, these tasks robustly activate not only gray matter regions, but also white matter tracts. It is likely that the response hand itself (dominant or non-dominant) modulates gray and white matter activations during within and inter-hemispheric transfer. Yet the role of uni-manual responses and/or right hand dominance in modulating brain activations during such basic tasks is unclear. Here we investigated how uni-manual responses with either hand modulated activations during a basic visuo-motor task (the established Poffenberger paradigm) alternating between inter- and within-hemispheric transfer conditions. In a large sample of strongly right-handed adults (n = 49), we used a factorial combination of transfer condition [Inter vs. Within] and response hand [Dominant(Right) vs. Non-Dominant (Left)] to discover fMRI-based activations in gray matter, and in narrowly defined white matter tracts. These tracts were identified using a priori probabilistic white matter atlases. Uni-manual responses with the right hand strongly modulated activations in gray matter, and notably in white matter. Furthermore, when responding with the left hand, activations during inter-hemispheric transfer were strongly predicted by the degree of right-hand dominance, with increased right-handedness predicting decreased fMRI activation. Finally, increasing age within the middle-aged sample was associated with a decrease in activations. These results provide novel evidence of complex relationships between uni-manual responses in right-handed subjects, and activations during within- and inter-hemispheric transfer suggest that the organization of the motor system exerts sophisticated functional effects. Moreover, our evidence of activation in white matter tracts is consistent with prior studies, confirming fMRI-detectable white matter activations which are systematically modulated by experimental condition.
Yesterday's Extraordinary Research Yields Today's Ordinary Principles
ERIC Educational Resources Information Center
Thomas, Mary Norris
2005-01-01
Ordinary performance improvement tips, techniques, and principles that are taken for granted today have their roots in extraordinary research. Today, the learning principle that states that things that occur together tend to be recalled together is widely accepted, and this principle of association as an instructional technique is often used. How…
Rotorcraft Airloads Measurements - Extraordinary Costs, Extraordinary Benefits
2014-08-01
obtained in the 1980s by the PETRA collider in a high-energy physics lab near Hamburg, Germany. The project, called JADE, was an international...and R. M. Martin . 1990. Aerodynamic and Acoustic Test of a United Technologies Scale Model Rotor at DNW. Amer. Hel. Soc. 46th Annual Forum, Wash
On the Un-Becoming of Measurement in Education
ERIC Educational Resources Information Center
Davids, Nuraan
2017-01-01
Education in democratic South Africa has been saddled with the extraordinary task of sanitising a once dehumanising and splintered education system into a singular narrative of social justice and creative, problem-solving individuals. This extraordinary effort has witnessed a pendulum swing from the openness of outcomes-based education, to a less…
Federal Register 2010, 2011, 2012, 2013, 2014
2013-02-12
... Market Volatility 2. * * * * * * * * Interpretations and Policies: * * * * * .03 The provisions of this... initial date of operations of the Regulation NMS Plan to Address Extraordinary Market Volatility or....3C, Individual Stock Trading Pauses Due to Extraordinary Market Volatility, was approved by the...
33 CFR 151.1514 - Ballast water management alternatives under extraordinary conditions.
Code of Federal Regulations, 2010 CFR
2010-07-01
... failure, or other extraordinary conditions, is unable to effect a ballast water exchange before entering... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Ballast water management... SUBSTANCES, GARBAGE, MUNICIPAL OR COMMERCIAL WASTE, AND BALLAST WATER Ballast Water Management for Control of...
33 CFR 151.1514 - Ballast water management alternatives under extraordinary conditions.
Code of Federal Regulations, 2011 CFR
2011-07-01
... failure, or other extraordinary conditions, is unable to effect a ballast water exchange before entering... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Ballast water management... SUBSTANCES, GARBAGE, MUNICIPAL OR COMMERCIAL WASTE, AND BALLAST WATER Ballast Water Management for Control of...
45 CFR 670.5 - Exception in extraordinary circumstances.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 45 Public Welfare 3 2010-10-01 2010-10-01 false Exception in extraordinary circumstances. 670.5 Section 670.5 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE... involving the safety of human life or of ships, aircraft, or equipment or facilities of high value, or the...
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Records. 50.101-3 Section... EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Extraordinary Contractual Actions 50.101-3 Records. Agencies shall maintain complete records of all actions taken under this Subpart 50.1. For each request for...
Code of Federal Regulations, 2011 CFR
2011-10-01
... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Records. 50.101-3 Section... EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Extraordinary Contractual Actions 50.101-3 Records. Agencies shall maintain complete records of all actions taken under this Subpart 50.1. For each request for...
Code of Federal Regulations, 2012 CFR
2012-10-01
... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Records. 50.101-3 Section... EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Extraordinary Contractual Actions 50.101-3 Records. Agencies shall maintain complete records of all actions taken under this Subpart 50.1. For each request for...
Code of Federal Regulations, 2014 CFR
2014-10-01
... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Records. 50.101-3 Section... EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Extraordinary Contractual Actions 50.101-3 Records. Agencies shall maintain complete records of all actions taken under this Subpart 50.1. For each request for...
Code of Federal Regulations, 2012 CFR
2012-01-01
... 10 Energy 4 2012-01-01 2012-01-01 false Procedures. 840.2 Section 840.2 Energy DEPARTMENT OF ENERGY EXTRAORDINARY NUCLEAR OCCURRENCES § 840.2 Procedures. (a) DOE may initiate, on its own motion, the making of a determination as to whether or not there has been an extraordinary nuclear occurrence. In the...
Code of Federal Regulations, 2013 CFR
2013-01-01
... 10 Energy 4 2013-01-01 2013-01-01 false Procedures. 840.2 Section 840.2 Energy DEPARTMENT OF ENERGY EXTRAORDINARY NUCLEAR OCCURRENCES § 840.2 Procedures. (a) DOE may initiate, on its own motion, the making of a determination as to whether or not there has been an extraordinary nuclear occurrence. In the...
48 CFR 750.7110-2 - Office of General Counsel coordination.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Office of General Counsel coordination. 750.7110-2 Section 750.7110-2 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions To Protect Foreign Policy Interests of th...
45 CFR 670.5 - Exception in extraordinary circumstances.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 45 Public Welfare 3 2014-10-01 2014-10-01 false Exception in extraordinary circumstances. 670.5 Section 670.5 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE... involving the safety of human life or of ships, aircraft, or equipment or facilities of high value, or the...
45 CFR 670.5 - Exception in extraordinary circumstances.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 45 Public Welfare 3 2013-10-01 2013-10-01 false Exception in extraordinary circumstances. 670.5 Section 670.5 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE... involving the safety of human life or of ships, aircraft, or equipment or facilities of high value, or the...
45 CFR 670.5 - Exception in extraordinary circumstances.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 45 Public Welfare 3 2011-10-01 2011-10-01 false Exception in extraordinary circumstances. 670.5 Section 670.5 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE... involving the safety of human life or of ships, aircraft, or equipment or facilities of high value, or the...
45 CFR 670.5 - Exception in extraordinary circumstances.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 45 Public Welfare 3 2012-10-01 2012-10-01 false Exception in extraordinary circumstances. 670.5 Section 670.5 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE... involving the safety of human life or of ships, aircraft, or equipment or facilities of high value, or the...
Code of Federal Regulations, 2010 CFR
2010-01-01
... 10 Energy 4 2010-01-01 2010-01-01 false Procedures. 840.2 Section 840.2 Energy DEPARTMENT OF ENERGY EXTRAORDINARY NUCLEAR OCCURRENCES § 840.2 Procedures. (a) DOE may initiate, on its own motion, the making of a determination as to whether or not there has been an extraordinary nuclear occurrence. In the...
Code of Federal Regulations, 2011 CFR
2011-01-01
... 10 Energy 4 2011-01-01 2011-01-01 false Procedures. 840.2 Section 840.2 Energy DEPARTMENT OF ENERGY EXTRAORDINARY NUCLEAR OCCURRENCES § 840.2 Procedures. (a) DOE may initiate, on its own motion, the making of a determination as to whether or not there has been an extraordinary nuclear occurrence. In the...
Brain Growth Rate Abnormalities Visualized in Adolescents with Autism
Hua, Xue; Thompson, Paul M.; Leow, Alex D.; Madsen, Sarah K.; Caplan, Rochelle; Alger, Jeffry R.; O’Neill, Joseph; Joshi, Kishori; Smalley, Susan L.; Toga, Arthur W.; Levitt, Jennifer G.
2014-01-01
Autism spectrum disorder (ASD) is a heterogeneous disorder of brain development with wide-ranging cognitive deficits. Typically diagnosed before age 3, ASD is behaviorally defined but patients are thought to have protracted alterations in brain maturation. With longitudinal magnetic resonance imaging (MRI), we mapped an anomalous developmental trajectory of the brains of autistic compared to those of typically developing children and adolescents. Using tensor-based morphometry (TBM), we created 3D maps visualizing regional tissue growth rates based on longitudinal brain MRI scans of 13 autistic and 7 typically developing boys (mean age/inter-scan interval: autism 12.0 ± 2.3 years/2.9 ± 0.9 years; control 12.3 ± 2.4/2.8 ± 0.8). The typically developing boys demonstrated strong whole-brain white matter growth during this period, but the autistic boys showed abnormally slowed white matter development (p = 0.03, corrected), especially in the parietal (p = 0.008), temporal (p = 0.03) and occipital lobes (p =0.02). We also visualized abnormal overgrowth in autism in some gray matter structures, such as the putamen and anterior cingulate cortex. Our findings reveal aberrant growth rates in brain regions implicated in social impairment, communication deficits and repetitive behaviors in autism, suggesting that growth rate abnormalities persist into adolescence. TBM revealed persisting growth rate anomalies long after diagnosis, which has implications for evaluation of therapeutic effects. PMID:22021093
Brain growth rate abnormalities visualized in adolescents with autism.
Hua, Xue; Thompson, Paul M; Leow, Alex D; Madsen, Sarah K; Caplan, Rochelle; Alger, Jeffry R; O'Neill, Joseph; Joshi, Kishori; Smalley, Susan L; Toga, Arthur W; Levitt, Jennifer G
2013-02-01
Autism spectrum disorder is a heterogeneous disorder of brain development with wide ranging cognitive deficits. Typically diagnosed before age 3, autism spectrum disorder is behaviorally defined but patients are thought to have protracted alterations in brain maturation. With longitudinal magnetic resonance imaging (MRI), we mapped an anomalous developmental trajectory of the brains of autistic compared with those of typically developing children and adolescents. Using tensor-based morphometry, we created 3D maps visualizing regional tissue growth rates based on longitudinal brain MRI scans of 13 autistic and seven typically developing boys (mean age/interscan interval: autism 12.0 ± 2.3 years/2.9 ± 0.9 years; control 12.3 ± 2.4/2.8 ± 0.8). The typically developing boys demonstrated strong whole brain white matter growth during this period, but the autistic boys showed abnormally slowed white matter development (P = 0.03, corrected), especially in the parietal (P = 0.008), temporal (P = 0.03), and occipital lobes (P = 0.02). We also visualized abnormal overgrowth in autism in gray matter structures such as the putamen and anterior cingulate cortex. Our findings reveal aberrant growth rates in brain regions implicated in social impairment, communication deficits and repetitive behaviors in autism, suggesting that growth rate abnormalities persist into adolescence. Tensor-based morphometry revealed persisting growth rate anomalies long after diagnosis, which has implications for evaluation of therapeutic effects. Copyright © 2011 Wiley Periodicals, Inc.
West, Greg L; Drisdelle, Brandi Lee; Konishi, Kyoko; Jackson, Jonathan; Jolicoeur, Pierre; Bohbot, Veronique D
2015-06-07
The habitual playing of video games is associated with increased grey matter and activity in the striatum. Studies in humans and rodents have shown an inverse relationship between grey matter in the striatum and hippocampus. We investigated whether action video game playing is also associated with increased use of response learning strategies during navigation, known to be dependent on the caudate nucleus of the striatum, when presented in a dual solution task. We tested 26 action video game players (actionVGPs) and 33 non-action video game players (nonVGPs) on the 4-on-8 virtual maze and a visual attention event-related potential (ERP) task, which elicits a robust N-2-posterior-controlateral (N2pc) component. We found that actionVGPs had a significantly higher likelihood of using a response learning strategy (80.76%) compared to nonVGPs (42.42%). Consistent with previous evidence, actionVGPs and nonVGPs differed in the way they deployed visual attention to central and peripheral targets as observed in the elicited N2pc component during an ERP visual attention task. Increased use of the response strategy in actionVGPs is consistent with previously observed increases in striatal volume in video game players (VGPs). Using response strategies is associated with decreased grey matter in the hippocampus. Previous studies have shown that decreased volume in the hippocampus precedes the onset of many neurological and psychiatric disorders. If actionVGPs have lower grey matter in the hippocampus, as response learners normally do, then these individuals could be at increased risk of developing neurological and psychiatric disorders during their lifetime. © 2015 The Author(s) Published by the Royal Society. All rights reserved.
West, Greg L.; Drisdelle, Brandi Lee; Konishi, Kyoko; Jackson, Jonathan; Jolicoeur, Pierre; Bohbot, Veronique D.
2015-01-01
The habitual playing of video games is associated with increased grey matter and activity in the striatum. Studies in humans and rodents have shown an inverse relationship between grey matter in the striatum and hippocampus. We investigated whether action video game playing is also associated with increased use of response learning strategies during navigation, known to be dependent on the caudate nucleus of the striatum, when presented in a dual solution task. We tested 26 action video game players (actionVGPs) and 33 non-action video game players (nonVGPs) on the 4-on-8 virtual maze and a visual attention event-related potential (ERP) task, which elicits a robust N-2-posterior-controlateral (N2pc) component. We found that actionVGPs had a significantly higher likelihood of using a response learning strategy (80.76%) compared to nonVGPs (42.42%). Consistent with previous evidence, actionVGPs and nonVGPs differed in the way they deployed visual attention to central and peripheral targets as observed in the elicited N2pc component during an ERP visual attention task. Increased use of the response strategy in actionVGPs is consistent with previously observed increases in striatal volume in video game players (VGPs). Using response strategies is associated with decreased grey matter in the hippocampus. Previous studies have shown that decreased volume in the hippocampus precedes the onset of many neurological and psychiatric disorders. If actionVGPs have lower grey matter in the hippocampus, as response learners normally do, then these individuals could be at increased risk of developing neurological and psychiatric disorders during their lifetime. PMID:25994669
Bells, Sonya; Lefebvre, Jérémie; Prescott, Steven A; Dockstader, Colleen; Bouffet, Eric; Skocic, Jovanka; Laughlin, Suzanne; Mabbott, Donald J
2017-08-23
Cognition is compromised by white matter (WM) injury but the neurophysiological alterations linking them remain unclear. We hypothesized that reduced neural synchronization caused by disruption of neural signal propagation is involved. To test this, we evaluated group differences in: diffusion tensor WM microstructure measures within the optic radiations, primary visual area (V1), and cuneus; neural phase synchrony to a visual attention cue during visual-motor task; and reaction time to a response cue during the same task between 26 pediatric patients (17/9: male/female) treated with cranial radiation treatment for a brain tumor (12.67 ± 2.76 years), and 26 healthy children (16/10: male/female; 12.01 ± 3.9 years). We corroborated our findings using a corticocortical computational model representing perturbed signal conduction from myelin. Patients show delayed reaction time, WM compromise, and reduced phase synchrony during visual attention compared with healthy children. Notably, using partial least-squares-path modeling we found that WM insult within the optic radiations, V1, and cuneus is a strong predictor of the slower reaction times via disruption of neural synchrony in visual cortex. Observed changes in synchronization were reproduced in a computational model of WM injury. These findings provide new evidence linking cognition with WM via the reliance of neural synchronization on propagation of neural signals. SIGNIFICANCE STATEMENT By comparing brain tumor patients to healthy children, we establish that changes in the microstructure of the optic radiations and neural synchrony during visual attention predict reaction time. Furthermore, by testing the directionality of these links through statistical modeling and verifying our findings with computational modeling, we infer a causal relationship, namely that changes in white matter microstructure impact cognition in part by disturbing the ability of neural assemblies to synchronize. Together, our human imaging data and computer simulations show a fundamental connection between WM microstructure and neural synchronization that is critical for cognitive processing. Copyright © 2017 the authors 0270-6474/17/378227-12$15.00/0.
Unfitness to stand trial decision-making in the extraordinary Chambers in the Courts of Cambodia.
Freckelton, Ian; Karagiannakis, Magda
2014-06-01
In the small number of trials for matters such as genocide and crimes against humanity that have taken place before the Extraordinary Chambers in the Courts of Cambodia, by 2014 three occasions had arisen in which the fitness of the accused persons to participate in their trials had become contentious. This is hardly surprising given that the key period of Khmer Rouge government occurred a very long while ago--between 1975 and 1979. The accused persons are all aged. In two instances, the Trial Chamber of the Courts of its own motion sought expert evaluations of the accused persons' fitness to stand trial and, promptly, upon receipt of such reports, determined them to be fit by reference to criteria utilised by the Appeal Chamber of the International Criminal Court for the Former Yugoslavia (the ICTY). In the other instance an accused person, leng Thirith, was found unfit to stand trial and a range of important issues was traversed as to the measures that can properly be taken to try to render a person fit for trial and how legitimate the imposition of detention for that purpose is, and then how legitimate encroachments on a person's civil liberties are to monitor them if there is only a remote possibility that their mental state might improve. It is likely that the balance adopted by the Supreme Court Chamber in the Courts of Cambodia in making significant efforts to render an accused person fit for trial and then in continuing to monitor their mental state when such efforts do not bear fruit, instead of simply releasing them back into the community, will stand as an important precedent for future occasions under international criminal law when issues of fitness to stand trial and how they should be handled arise.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Mandal, P.; Anantha Ramakrishna, S.; Patil, Raj
2013-12-14
An array of H-shaped subwavelength slits in a plasmonic film has a polarization dependent extra-ordinary transmission due to shape anisotropy. Non-overlapping extra-ordinary transmission bands for the orthogonal linear polarization states of the input light are used to demonstrate a polarization dependent color switch. The fabricated array of submicron sized H-slits on a gold film displayed two transmission bands for the linear x- and y-polarized light at visible (650–850 nm) and near-infra-red (1150–1450 nm) bands, respectively. The relative transmitted light in these two bands can be controlled by changing the linear polarization state of the input radiation from 0° to 90°.
Early-Stage Visual Processing and Cortical Amplification Deficits in Schizophrenia
Butler, Pamela D.; Zemon, Vance; Schechter, Isaac; Saperstein, Alice M.; Hoptman, Matthew J.; Lim, Kelvin O.; Revheim, Nadine; Silipo, Gail; Javitt, Daniel C.
2005-01-01
Background Patients with schizophrenia show deficits in early-stage visual processing, potentially reflecting dysfunction of the magnocellular visual pathway. The magnocellular system operates normally in a nonlinear amplification mode mediated by glutamatergic (N-methyl-d-aspartate) receptors. Investigating magnocellular dysfunction in schizophrenia therefore permits evaluation of underlying etiologic hypotheses. Objectives To evaluate magnocellular dysfunction in schizophrenia, relative to known neurochemical and neuroanatomical substrates, and to examine relationships between electrophysiological and behavioral measures of visual pathway dysfunction and relationships with higher cognitive deficits. Design, Setting, and Participants Between-group study at an inpatient state psychiatric hospital and out-patient county psychiatric facilities. Thirty-three patients met DSM-IV criteria for schizophrenia or schizoaffective disorder, and 21 nonpsychiatric volunteers of similar ages composed the control group. Main Outcome Measures (1) Magnocellular and parvocellular evoked potentials, analyzed using nonlinear (Michaelis-Menten) and linear contrast gain approaches; (2) behavioral contrast sensitivity measures; (3) white matter integrity; (4) visual and nonvisual neuropsychological measures, and (5) clinical symptom and community functioning measures. Results Patients generated evoked potentials that were significantly reduced in response to magnocellular-biased, but not parvocellular-biased, stimuli (P=.001). Michaelis-Menten analyses demonstrated reduced contrast gain of the magnocellular system (P=.001). Patients showed decreased contrast sensitivity to magnocellular-biased stimuli (P<.001). Evoked potential deficits were significantly related to decreased white matter integrity in the optic radiations (P<.03). Evoked potential deficits predicted impaired contrast sensitivity (P=.002), which was in turn related to deficits in complex visual processing (P≤.04). Both evoked potential (P≤.04) and contrast sensitivity (P=.01) measures significantly predicted community functioning. Conclusions These findings confirm the existence of early-stage visual processing dysfunction in schizophrenia and provide the first evidence that such deficits are due to decreased nonlinear signal amplification, consistent with glutamatergic theories. Neuroimaging studies support the hypothesis of dysfunction within low-level visual pathways involving thalamocortical radiations. Deficits in early-stage visual processing significantly predict higher cognitive deficits. PMID:15867102
32 CFR 150.20 - Petitions for extraordinary relief, answer, and reply.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 32 National Defense 1 2013-07-01 2013-07-01 false Petitions for extraordinary relief, answer, and reply. 150.20 Section 150.20 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE... each party respondent and will contain: (1) A previous history of the case including whether prior...
32 CFR 150.20 - Petitions for extraordinary relief, answer, and reply.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 32 National Defense 1 2012-07-01 2012-07-01 false Petitions for extraordinary relief, answer, and reply. 150.20 Section 150.20 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE... each party respondent and will contain: (1) A previous history of the case including whether prior...
32 CFR 150.20 - Petitions for extraordinary relief, answer, and reply.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 32 National Defense 1 2011-07-01 2011-07-01 false Petitions for extraordinary relief, answer, and reply. 150.20 Section 150.20 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE... each party respondent and will contain: (1) A previous history of the case including whether prior...
32 CFR 150.20 - Petitions for extraordinary relief, answer, and reply.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 32 National Defense 1 2014-07-01 2014-07-01 false Petitions for extraordinary relief, answer, and reply. 150.20 Section 150.20 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE... each party respondent and will contain: (1) A previous history of the case including whether prior...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-02-12
... FINRA is proposing to amend FINRA Rule 6121 (Trading Halts Due to Extraordinary Market Volatility) to... Market Volatility or February 4, 2014. The text of the proposed rule change is available on FINRA's Web... for trading pauses in individual securities due to extraordinary market volatility, to extend the...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-08-16
... volatility, if adopted, applies]. During the pilot, the term ``Circuit Breaker Securities'' shall mean all.... (collectively, the ``Exchanges''), to pause trading during periods of extraordinary market volatility in S&P 500... extraordinary market volatility, if adopted, applies.\\7\\ On June 23, 2011, the Commission approved the expansion...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-08-26
... Proposed Rule Change NASDAQ proposes to extend the pilot period of Rule 4753(c), NASDAQ's ``Volatility... approved, a limit up/limit down mechanism to address extraordinary market volatility, is approved. The text... to address extraordinary market volatility, is approved [six months after the date of Commission...
9 CFR 82.16 - Extraordinary emergencies; applicability of regulations.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Extraordinary emergencies; applicability of regulations. 82.16 Section 82.16 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE INTERSTATE TRANSPORTATION OF ANIMALS (INCLUDING POULTRY) AND ANIMAL PRODUCTS EXOTIC NEWCASTLE DIS- EASE (END) AN...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-06-16
... listing market has resolved any imbalances. See, e.g., BlackRock Letter, Credit Suisse Letter, Knight... to Proposed Rule Change To Amend FINRA Rule 6121 (Trading Halts Due to Extraordinary Market... Listing Market Has Issued a Trading Pause Due to Extraordinary Market Conditions June 10, 2010. I...
Art Influencing Art: The Making of "An Extraordinary Life."
ERIC Educational Resources Information Center
Kerper, Richard M.
2002-01-01
Explores the creation of "An Extraordinary Life: The Story of a Monarch Butterfly." Selects this book because of the unprecedented decision to give the 1998 Orbis Pictus Award to both the author and the illustrator for a work in which text and illustration melded together. Develops an event model, revealing the creation of this…
Code of Federal Regulations, 2010 CFR
2010-10-01
... contracts involving both research and development and other work. 250.104-3-70 Section 250.104-3-70 Federal... MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS AND THE SAFETY ACT Extraordinary Contractual Actions 250.104-3-70 Indemnification under contracts involving both research and development and other work. When...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-08-16
... Rule Change To Extend Pilot Program Related to Trading Pauses Due to Extraordinary Market Volatility... Volatility.'' The text of the proposed rule change is available at the Exchange's Web site at http://www.../limit down mechanism to address extraordinary market volatility, if adopted, applies. The Exchange...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-08-16
... to Extraordinary Market Volatility August 10, 2011. Pursuant to Section 19(b)(1) of the Securities... regarding trading pauses in individual securities due to extraordinary market volatility. The text of the... market volatility under NSX Rule 11.20B. Currently, unless otherwise extended or approved permanently...
Code of Federal Regulations, 2014 CFR
2014-07-01
... exceptions to the administrative law judge's decision; decisions by the Board; extraordinary postdecisional motions. 102.48 Section 102.48 Labor Regulations Relating to Labor NATIONAL LABOR RELATIONS BOARD RULES... to file exceptions to the administrative law judge's decision; decisions by the Board; extraordinary...
Code of Federal Regulations, 2012 CFR
2012-07-01
... exceptions to the administrative law judge's decision; decisions by the Board; extraordinary postdecisional motions. 102.48 Section 102.48 Labor Regulations Relating to Labor NATIONAL LABOR RELATIONS BOARD RULES... to file exceptions to the administrative law judge's decision; decisions by the Board; extraordinary...
Code of Federal Regulations, 2013 CFR
2013-07-01
... exceptions to the administrative law judge's decision; decisions by the Board; extraordinary postdecisional motions. 102.48 Section 102.48 Labor Regulations Relating to Labor NATIONAL LABOR RELATIONS BOARD RULES... to file exceptions to the administrative law judge's decision; decisions by the Board; extraordinary...
Developing Concepts of Ordinary and Extraordinary Communication
ERIC Educational Resources Information Center
Lane, Jonathan D.; Evans, E. Margaret; Brink, Kimberly A.; Wellman, Henry M.
2016-01-01
We examine how understandings of ordinary and extraordinary communication develop. Three- to 10-year-old children and adults (N = 183) were given scenarios in which a protagonist wanted help from a human (their parent) or from God. Scenarios varied in whether protagonists expressed their desires aloud (by asking) or silently (by hoping), whether…
Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-28
... Effectiveness of the Second Amendment to the National Market System Plan to Address Extraordinary Market...-631) (Order Approving, on a Pilot Basis, the National Market System Plan To Address Extraordinary... accommodate more fundamental price moves (as opposed to erroneous trades or momentary gaps in liquidity). All...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-28
... Amendment to the National Market System Plan to Address Extraordinary Market Volatility, File No. 4-631... Market System Plan To Address Extraordinary Market Volatility). \\7\\ See Securities Exchange Act Release... requirements of the Plan are coupled with Trading Pauses to accommodate more fundamental price moves (as...
18 CFR 367.4350 - Account 435, Extraordinary deductions.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Account 435, Extraordinary deductions. 367.4350 Section 367.4350 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE PUBLIC UTILITY HOLDING COMPANY ACT OF 2005, FEDERAL POWER ACT AND NATURAL GAS ACT...
18 CFR 367.4340 - Account 434, Extraordinary income.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Account 434, Extraordinary income. 367.4340 Section 367.4340 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE PUBLIC UTILITY HOLDING COMPANY ACT OF 2005, FEDERAL POWER ACT AND NATURAL GAS ACT UNIFOR...
NASA Astrophysics Data System (ADS)
Jaffe, R. L.
2008-05-01
Resonances and enhancements in meson-meson scattering can be divided into two classes distinguished by their behavior as the number of colors (Nc) in QCD becomes large: The first are ordinary mesons that become stable as Nc → ∞. This class includes textbook qbar q mesons as well as glueballs and hybrids. The second class, extraordinary mesons, are enhancements that disappear as Nc → ∞; they subside into the hadronic continuum. This class includes indistinct and controversial objects that have been classified as qbarqbar qq mesons or meson-meson molecules. Peláez's study of the Nc dependence of unitarized chiral dynamics illustrates both classes: the p-wave ππ and Kπ resonances, the ρ (770) and K∗ (892), behave as ordinary mesons; the s-wave ππ and Kπ enhancements, the σ (600) and κ (800), behave like extraordinary mesons. Ordinary mesons resemble Feshbach resonances while extraordinary mesons look more like effects due to potentials in meson-meson scattering channels. I build and explore toy models along these lines. Finally I discuss some related dynamical issues affecting the interpretation of extraordinary mesons.
Wu, Jiaye; Yang, Xiangbo
2017-10-30
In this paper, we construct a 1D PT-symmetric Thue-Morse aperiodic optical waveguide network (PTSTMAOWN) and mainly investigate the ultrastrong extraordinary transmission and reflection. We propose an approach to study the photonic modes and solve the problem of calculating photonic modes distributions in aperiodic networks due to the lack of dispersion functions and find that in a PTSTMAOWN there exist more photonic modes and more spontaneous PT-symmetric breaking points, which are quite different from other reported PT-symmetric optical systems. Additionally, we develop a method to sort spontaneous PT-symmetric breaking point zones to seek the strongest extraordinary point and obtain that at this point the strongest extraordinary transmission and reflection arrive at 2.96316 × 10 5 and 1.32761 × 10 5 , respectively, due to the PT-symmetric coupling resonance and the special symmetry pattern of TM networks. These enormous gains are several orders of magnitude larger than the previous results. This optical system may possess potential in designing optical amplifier, optical logic elements in photon computers and ultrasensitive optical switches with ultrahigh monochromatity.
Minimally invasive trans-portal resection of deep intracranial lesions.
Raza, S M; Recinos, P F; Avendano, J; Adams, H; Jallo, G I; Quinones-Hinojosa, A
2011-02-01
The surgical management of deep intra-axial lesions still requires microsurgical approaches that utilize retraction of deep white matter to obtain adequate visualization. We report our experience with a new tubular retractor system, designed specifically for intracranial applications, linked with frameless neuronavigation for a cohort of intraventricular and deep intra-axial tumors. The ViewSite Brain Access System (Vycor, Inc) was used in a series of 9 adult and pediatric patients with a variety of pathologies. Histological diagnoses either resected or biopsied with the system included: colloid cyst, DNET, papillary pineal tumor, anaplastic astrocytoma, toxoplasmosis and lymphoma. The locations of the lesions approached include: lateral ventricle, basal ganglia, pulvinar/posterior thalamus and insular cortex. Post-operative imaging was assessed to determine extent of resection and extent of white matter damage along the surgical trajectory (based on T (2)/FLAIR and diffusion restriction/ADC signal). Satisfactory resection or biopsy was obtained in all patients. Radiographic analysis demonstrated evidence of white matter damage along the surgical trajectory in one patient. None of the patients experienced neurological deficits as a result of white matter retraction/manipulation. Based on a retrospective review of our experience, we feel that this access system, when used in conjunction with frameless neuronavigational systems, provides adequate visualization for tumor resection while permitting the use of standard microsurgical techniques through minimally invasive craniotomies. Our initial data indicate that this system may minimize white matter injury, but further studies are necessary. © Georg Thieme Verlag KG Stuttgart · New York.
Cerebellum and cognition in multiple sclerosis: the fall status matters.
Kalron, Alon; Allali, Gilles; Achiron, Anat
2018-04-01
Cerebellar volume has been linked with cognitive performances in MS; however, the association in terms of fall status has never been compared. Therefore, the objective of the current study was to compare cognitive performance with cerebellar volume between MS fallers and non-fallers. The cross-sectional study included 140 PwMS (96 women). MRI volumetric analysis was based on the FreeSurfer image analysis suite. Volumes of the cerebellar gray and white matter were identified as the region of interest. Cognitive function included scores obtained from a computerized cognitive battery of tests. The sample was divided into fallers and non-fallers. MS fallers demonstrated a lower global cognitive performance and reduced gray and white matter cerebellar volumes compared to non-fallers. A significant association was found between total gray and white matter cerebellar volume and visual spatial subdomain (P value = 0.044 and 0.032, respectively) in the non-fallers group. The association remained significant after controlling for the total cranial volume and neurological disability (P value = 0.026 and 0.047, respectively). A relationship was found between the visual spatial score and the left gray matter cerebellum volume; R 2 = 0.44, P value = 0.021. We believe that a unique relationship exists between the cerebellum structure and cognitive processing according to fall history in PwMS and should be considered when investigating the association between brain functioning and cognitive performances in MS.
Extraordinary optical transmission in nanopatterned ultrathin metal films without holes
Peer, Akshit; Biswas, Rana
2016-02-01
In this study, we experimentally and theoretically demonstrate that a continuous gold film on a periodically textured substrate exhibits extraordinary optical transmission, even though no holes were etched in the film. Our film synthesis started by nanoimprinting a periodic array of nanocups with a period of ~750 nm on a polystyrene film over a glass substrate. A thin non-conformal gold film was sputter-deposited on the polystyrene by angle-directed deposition. The gold film was continuous with spatial thickness variation, the film being thinnest at the bottom of the nanocup. Measurements revealed an extraordinary transmission peak at a wavelength just smaller thanmore » the period, with an enhancement of ~2.5 compared to the classically expected value. Scattering matrix simulations model well the transmission and reflectance measurements when an ultrathin gold layer (~5 nm), smaller than the skin depth is retained at the bottom of the nanocups. Electric field intensities are enhanced by >100 within the nanocup, and ~40 in the ultrathin gold layer causing transmission through it. We show a wavelength red-shift of ~30 nm in the extraordinary transmission peak when the nanocups are coated with a thin film of a few nanometers, which can be utilized for biosensing. The continuous corrugated metal films are far simpler structures to observe extraordinary transmission, circumventing the difficult process of etching the metal film. Such continuous metal films with ultrathin regions are simple platforms for non-linear optics, plasmonics, and biological and chemical sensing.« less
Anatomical Coupling between Distinct Metacognitive Systems for Memory and Visual Perception
McCurdy, Li Yan; Maniscalco, Brian; Metcalfe, Janet; Liu, Ka Yuet; de Lange, Floris P.; Lau, Hakwan
2015-01-01
A recent study found that, across individuals, gray matter volume in the frontal polar region was correlated with visual metacognition capacity (i.e., how well one’s confidence ratings distinguish between correct and incorrect judgments). A question arises as to whether the putative metacognitive mechanisms in this region are also used in other metacognitive tasks involving, for example, memory. A novel psychophysical measure allowed us to assess metacognitive efficiency separately in a visual and a memory task, while taking variations in basic task performance capacity into account. We found that, across individuals, metacognitive efficiencies positively correlated between the two tasks. However, voxel-based morphometry analysis revealed distinct brain structures for the two kinds of metacognition. Replicating a previous finding, variation in visual metacognitive efficiency was correlated with volume of frontal polar regions. However, variation in memory metacognitive efficiency was correlated with volume of the precuneus. There was also a weak correlation between visual metacognitive efficiency and precuneus volume, which may account for the behavioral correlation between visual and memory metacognition (i.e., the precuneus may contain common mechanisms for both types of metacognition). However, we also found that gray matter volumes of the frontal polar and precuneus regions themselves correlated across individuals, and a formal model comparison analysis suggested that this structural covariation was sufficient to account for the behavioral correlation of metacognition in the two tasks. These results highlight the importance of the precuneus in higher-order memory processing and suggest that there may be functionally distinct metacognitive systems in the human brain. PMID:23365229
Boonruab, Jurairat; Nimpitakpong, Netraya; Damjuti, Watchara
2018-01-01
This randomized controlled trial aimed to investigate the distinctness after treatment among hot herbal compress, hot compress, and topical diclofenac. The registrants were equally divided into groups and received the different treatments including hot herbal compress, hot compress, and topical diclofenac group, which served as the control group. After treatment courses, Visual Analog Scale and 36-Item Short Form Health survey were, respectively, used to establish the level of pain intensity and quality of life. In addition, cervical range of motion and pressure pain threshold were also examined to identify the motional effects. All treatments showed significantly decreased level of pain intensity and increased cervical range of motion, while the intervention groups exhibited extraordinary capability compared with the topical diclofenac group in pressure pain threshold and quality of life. In summary, hot herbal compress holds promise to be an efficacious treatment parallel to hot compress and topical diclofenac.
Accomplishments and challenges of surgical simulation.
Satava, R M
2001-03-01
For nearly a decade, advanced computer technologies have created extraordinary educational tools using three-dimensional (3D) visualization and virtual reality. Pioneering efforts in surgical simulation with these tools have resulted in a first generation of simulators for surgical technical skills. Accomplishments include simulations with 3D models of anatomy for practice of surgical tasks, initial assessment of student performance in technical skills, and awareness by professional societies of potential in surgical education and certification. However, enormous challenges remain, which include improvement of technical fidelity, standardization of accurate metrics for performance evaluation, integration of simulators into a robust educational curriculum, stringent evaluation of simulators for effectiveness and value added to surgical training, determination of simulation application to certification of surgical technical skills, and a business model to implement and disseminate simulation successfully throughout the medical education community. This review looks at the historical progress of surgical simulators, their accomplishments, and the challenges that remain.
Short-term phenotypic plasticity in long-chain cuticular hydrocarbons
Thomas, Melissa L.; Simmons, Leigh W.
2011-01-01
Cuticular hydrocarbons provide arthropods with the chemical equivalent of the visually extravagant plumage of birds. Their long chain length, together with the number and variety of positions in which methyl branches and double bonds occur, provide cuticular hydrocarbons with an extraordinary level of information content. Here, we demonstrate phenotypic plasticity in an individual's cuticular hydrocarbon profile. Using solid-phase microextraction, a chemical technique that enables multiple sampling of the same individual, we monitor short-term changes in cuticular hydrocarbon profiles of individual crickets, Teleogryllus oceanicus, in response to a social challenge. We experimentally manipulate the dominance status of males and find that dominant males, on losing fights with other dominant males, change their hydrocarbon profile to more closely resemble that of a subordinate. This result demonstrates that cuticular hydrocarbons can be far more responsive to changes in social dominance than previously realized. PMID:21367785
The enhancement of visuospatial processing efficiency through Buddhist Deity meditation.
Kozhevnikov, Maria; Louchakova, Olga; Josipovic, Zoran; Motes, Michael A
2009-05-01
This study examined the effects of meditation on mental imagery, evaluating Buddhist monks' reports concerning their extraordinary imagery skills. Practitioners of Buddhist meditation were divided into two groups according to their preferred meditation style: Deity Yoga (focused attention on an internal visual image) or Open Presence (evenly distributed attention, not directed to any particular object). Both groups of meditators completed computerized mental-imagery tasks before and after meditation. Their performance was compared with that of control groups, who either rested or performed other visuospatial tasks between testing sessions. The results indicate that all the groups performed at the same baseline level, but after meditation, Deity Yoga practitioners demonstrated a dramatic increase in performance on imagery tasks compared with the other groups. The results suggest that Deity meditation specifically trains one's capacity to access heightened visuospatial processing resources, rather than generally improving visuospatial imagery abilities.
The nature of Trojan asteroid 624 Hektor
NASA Technical Reports Server (NTRS)
Hartmann, W. K.; Cruikshank, D. P.
1978-01-01
Near-simultaneous visual and thermal IR (20-micron) photometry of the Trojan asteroid 624 Hektor is reported which was performed when the asteroid was observed nearly along its rotation axis. The results confirm and refine the low albedo and large size of this asteroid and confirm the general rotational-pole position and aspect angle predicted by Dunlap and Gehrels (1969). Hektor is found to be a truly extraordinary object in that it is larger and far more irregular in shape than other measured Trojans and far more irregular than other belt asteroids of comparable size. It is proposed that Hektor could be a partially coalesced pair of Trojan asteroids which collided with energy too low to cause complete fragmentation, thus forming a dumbbell-shaped object. A possible scenario is outlined according to which the two pre-Hektor objects were neighboring relatively large primitive spheroidal planetesimals trapped in Jupiter's Lagrangian cloud. Observational and theoretical tests of this model are suggested.
Goldman, Jennifer G; Stebbins, Glenn T; Dinh, Vy; Bernard, Bryan; Merkitch, Doug; deToledo-Morrell, Leyla; Goetz, Christopher G
2014-03-01
Visual hallucinations are frequent, disabling complications of advanced Parkinson's disease, but their neuroanatomical basis is incompletely understood. Previous structural brain magnetic resonance imaging studies suggest volume loss in the mesial temporal lobe and limbic regions in subjects with Parkinson's disease with visual hallucinations, relative to those without visual hallucinations. However, these studies have not always controlled for the presence of cognitive impairment or dementia, which are common co-morbidities of hallucinations in Parkinson's disease and whose neuroanatomical substrates may involve mesial temporal lobe and limbic regions. Therefore, we used structural magnetic resonance imaging to examine grey matter atrophy patterns associated with visual hallucinations, comparing Parkinson's disease hallucinators to Parkinson's disease non-hallucinators of comparable cognitive function. We studied 50 subjects with Parkinson's disease: 25 classified as current and chronic visual hallucinators and 25 as non-hallucinators, who were matched for cognitive status (demented or non-demented) and age (± 3 years). Subjects underwent (i) clinical evaluations; and (ii) brain MRI scans analysed using whole-brain voxel-based morphometry techniques. Clinically, the Parkinson's disease hallucinators did not differ in their cognitive classification or performance in any of the five assessed cognitive domains, compared with the non-hallucinators. The Parkinson's disease groups also did not differ significantly in age, motor severity, medication use or duration of disease. On imaging analyses, the hallucinators, all of whom experienced visual hallucinations, exhibited grey matter atrophy with significant voxel-wise differences in the cuneus, lingual and fusiform gyri, middle occipital lobe, inferior parietal lobule, and also cingulate, paracentral, and precentral gyri, compared with the non-hallucinators. Grey matter atrophy in the hallucinators occurred predominantly in brain regions responsible for processing visuoperceptual information including the ventral 'what' and dorsal 'where' pathways, which are important in object and facial recognition and identification of spatial locations of objects, respectively. Furthermore, the structural brain changes seen on magnetic resonance imaging occurred independently of cognitive function and age. Our findings suggest that when hallucinators and non-hallucinators are similar in their cognitive performance, the neural networks involving visuoperceptual pathways, rather than the mesial temporal lobe regions, distinctively contribute to the pathophysiology of visual hallucinations and may explain their predominantly visual nature in Parkinson's disease. Identification of distinct structural MRI differences associated with hallucinations in Parkinson's disease may permit earlier detection of at-risk patients and ultimately, development of therapies specifically targeting hallucinations and visuoperceptive functions.
Stebbins, Glenn T.; Dinh, Vy; Bernard, Bryan; Merkitch, Doug; deToledo-Morrell, Leyla; Goetz, Christopher G.
2014-01-01
Visual hallucinations are frequent, disabling complications of advanced Parkinson’s disease, but their neuroanatomical basis is incompletely understood. Previous structural brain magnetic resonance imaging studies suggest volume loss in the mesial temporal lobe and limbic regions in subjects with Parkinson’s disease with visual hallucinations, relative to those without visual hallucinations. However, these studies have not always controlled for the presence of cognitive impairment or dementia, which are common co-morbidities of hallucinations in Parkinson’s disease and whose neuroanatomical substrates may involve mesial temporal lobe and limbic regions. Therefore, we used structural magnetic resonance imaging to examine grey matter atrophy patterns associated with visual hallucinations, comparing Parkinson’s disease hallucinators to Parkinson’s disease non-hallucinators of comparable cognitive function. We studied 50 subjects with Parkinson’s disease: 25 classified as current and chronic visual hallucinators and 25 as non-hallucinators, who were matched for cognitive status (demented or non-demented) and age (±3 years). Subjects underwent (i) clinical evaluations; and (ii) brain MRI scans analysed using whole-brain voxel-based morphometry techniques. Clinically, the Parkinson’s disease hallucinators did not differ in their cognitive classification or performance in any of the five assessed cognitive domains, compared with the non-hallucinators. The Parkinson’s disease groups also did not differ significantly in age, motor severity, medication use or duration of disease. On imaging analyses, the hallucinators, all of whom experienced visual hallucinations, exhibited grey matter atrophy with significant voxel-wise differences in the cuneus, lingual and fusiform gyri, middle occipital lobe, inferior parietal lobule, and also cingulate, paracentral, and precentral gyri, compared with the non-hallucinators. Grey matter atrophy in the hallucinators occurred predominantly in brain regions responsible for processing visuoperceptual information including the ventral ‘what’ and dorsal ‘where’ pathways, which are important in object and facial recognition and identification of spatial locations of objects, respectively. Furthermore, the structural brain changes seen on magnetic resonance imaging occurred independently of cognitive function and age. Our findings suggest that when hallucinators and non-hallucinators are similar in their cognitive performance, the neural networks involving visuoperceptual pathways, rather than the mesial temporal lobe regions, distinctively contribute to the pathophysiology of visual hallucinations and may explain their predominantly visual nature in Parkinson’s disease. Identification of distinct structural MRI differences associated with hallucinations in Parkinson’s disease may permit earlier detection of at-risk patients and ultimately, development of therapies specifically targeting hallucinations and visuoperceptive functions. PMID:24480486
Structure-Specific Statistical Mapping of White Matter Tracts
Yushkevich, Paul A.; Zhang, Hui; Simon, Tony; Gee, James C.
2008-01-01
We present a new model-based framework for the statistical analysis of diffusion imaging data associated with specific white matter tracts. The framework takes advantage of the fact that several of the major white matter tracts are thin sheet-like structures that can be effectively modeled by medial representations. The approach involves segmenting major tracts and fitting them with deformable geometric medial models. The medial representation makes it possible to average and combine tensor-based features along directions locally perpendicular to the tracts, thus reducing data dimensionality and accounting for errors in normalization. The framework enables the analysis of individual white matter structures, and provides a range of possibilities for computing statistics and visualizing differences between cohorts. The framework is demonstrated in a study of white matter differences in pediatric chromosome 22q11.2 deletion syndrome. PMID:18407524
Konstantinou, Nikos; Constantinidou, Fofi; Kanai, Ryota
2017-02-01
Working memory is responsible for keeping information in mind when it is no longer in view, linking perception with higher cognitive functions. Despite such crucial role, short-term maintenance of visual information is severely limited. Research suggests that capacity limits in visual short-term memory (VSTM) are correlated with sustained activity in distinct brain areas. Here, we investigated whether variability in the structure of the brain is reflected in individual differences of behavioral capacity estimates for spatial and object VSTM. Behavioral capacity estimates were calculated separately for spatial and object information using a novel adaptive staircase procedure and were found to be unrelated, supporting domain-specific VSTM capacity limits. Voxel-based morphometry (VBM) analyses revealed dissociable neuroanatomical correlates of spatial versus object VSTM. Interindividual variability in spatial VSTM was reflected in the gray matter density of the inferior parietal lobule. In contrast, object VSTM was reflected in the gray matter density of the left insula. These dissociable findings highlight the importance of considering domain-specific estimates of VSTM capacity and point to the crucial brain regions that limit VSTM capacity for different types of visual information. Hum Brain Mapp 38:767-778, 2017. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.
Human blindsight is mediated by an intact geniculo-extrastriate pathway
Ajina, Sara; Pestilli, Franco; Rokem, Ariel; Kennard, Christopher; Bridge, Holly
2015-01-01
Although damage to the primary visual cortex (V1) causes hemianopia, many patients retain some residual vision; known as blindsight. We show that blindsight may be facilitated by an intact white-matter pathway between the lateral geniculate nucleus and motion area hMT+. Visual psychophysics, diffusion-weighted magnetic resonance imaging and fibre tractography were applied in 17 patients with V1 damage acquired during adulthood and 9 age-matched controls. Individuals with V1 damage were subdivided into blindsight positive (preserved residual vision) and negative (no residual vision) according to psychophysical performance. All blindsight positive individuals showed intact geniculo-hMT+ pathways, while this pathway was significantly impaired or not measurable in blindsight negative individuals. Two white matter pathways previously implicated in blindsight: (i) superior colliculus to hMT+ and (ii) between hMT+ in each hemisphere were not consistently present in blindsight positive cases. Understanding the visual pathways crucial for residual vision may direct future rehabilitation strategies for hemianopia patients. DOI: http://dx.doi.org/10.7554/eLife.08935.001 PMID:26485034
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2013-02-04
... of Operations of the Regulation NMS Plan To Address Extraordinary Market Volatility or February 4... earlier of the initial date of operations of the Regulation NMS Plan to Address Extraordinary Market... operations on February 4, 2013 as currently planned, but will be delayed. If the Regulation NMS Plan to...
Studying Ordinary Events in a Field Devoted to the Extraordinary
ERIC Educational Resources Information Center
Coleman, Laurence J.
2014-01-01
Although a general understanding of the phenomenon of giftedness is evident in the literature, missing is a body of information on the thoughts and actions of gifted persons in those situations that we suspect influence the emergence of extraordinary accomplishment. In this article I propose a change in direction for the study of the advanced…
Federal Register 2010, 2011, 2012, 2013, 2014
2011-08-16
... which a limit up/limit down mechanism to address extraordinary market volatility, if adopted, applies...''), to pause trading during periods of extraordinary market volatility in S&P 500 stocks.\\3\\ The rules... market volatility, if adopted, applies.\\7\\ On June 23, 2011, the Commission approved the expansion of the...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-04
... Methodology for Determining When to Halt Trading Due to Extraordinary Market Volatility September 28, 2011... determining when to halt trading in all stocks due to extraordinary market volatility. The proposal is made in... market volatility. The Exchange is proposing this rule change in consultation with other equity, options...
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2011-04-12
... Volatility April 6, 2011. Pursuant to Section 19(b)(1) of the Securities Exchange Act of 1934 (the ``Act... ``Trading Halts Due to Extraordinary Market Volatility.'' The text of the proposed rule change is available... on which a limit up/limit down mechanism to address extraordinary market volatility, if adopted...
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2011-10-04
... to Extraordinary Market Volatility September 28, 2011. Pursuant to Section 19(b)(1) \\1\\ of the... market volatility. The text of the proposed rule change is available at the Exchange, the Commission's... when to halt trading in all stocks due to extraordinary market volatility. The Exchange is proposing...
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2011-06-29
... Changes Relating To Expanding the Pilot Rule for Trading Pauses Due to Extraordinary Market Volatility to... levels. This severe price volatility led to a large number of trades being executed at temporarily... intended to address extraordinary market volatility in NMS stocks. See Securities Exchange Act Release No...
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2011-10-04
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Code of Federal Regulations, 2011 CFR
2011-01-01
..., as amended, and the regulations issued by the Commission. 2.(a) For facilities designed for producing... occurrence including an extraordinary nuclear occurrence or series of occurrences at the location or in the... extraordinary nuclear occurrence or series of occurrences causing bodily injury, sickness, disease or death, or...
Code of Federal Regulations, 2014 CFR
2014-01-01
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Code of Federal Regulations, 2010 CFR
2010-01-01
..., as amended, and the regulations issued by the Commission. 2.(a) For facilities designed for producing... occurrence including an extraordinary nuclear occurrence or series of occurrences at the location or in the... extraordinary nuclear occurrence or series of occurrences causing bodily injury, sickness, disease or death, or...
Code of Federal Regulations, 2012 CFR
2012-01-01
..., as amended, and the regulations issued by the Commission. 2.(a) For facilities designed for producing... occurrence including an extraordinary nuclear occurrence or series of occurrences at the location or in the... extraordinary nuclear occurrence or series of occurrences causing bodily injury, sickness, disease or death, or...
Code of Federal Regulations, 2013 CFR
2013-01-01
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2011-08-16
... Rule Change to Extend Pilot Program Related to Trading Pauses Due to Extraordinary Market Volatility... Halts Due to Extraordinary Market Volatility.'' The text of the proposed rule change is available at the... volatility, if adopted, applies. The Exchange proposes to extend the pilot program to January 31, 2012. On...
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2011-04-12
... to Extraordinary Market Volatility April 6, 2011. Pursuant to Section 19(b)(1) of the Securities... volatility. The text of the proposed rule change is available on the Exchange's Web site at http://www.nsx... currently in effect regarding trading pauses in individual securities due to extraordinary market volatility...
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2011-05-12
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2012-08-02
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ERIC Educational Resources Information Center
Huber, Janice; Caine, Vera; Huber, Marilyn; Steeves, Pam
2013-01-01
As they wrote this article attentive to the focus of this volume of "Review of Research in Education" on "extraordinary pedagogies for working within school settings serving nondominant students" (C. Faltis & J. Abedi, 2011, personal communication), the authors held close understandings of ways in which narrative inquiry…
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2011-11-30
... Rule Change To Modify Exchange Rule 11.18 Relating to Trading Pauses Due to Extraordinary Market... proposal to amend Rule 11.18, entitled ``Trading Halts Due to Extraordinary Market Volatility.'' The text... Proposed Rule Change 1. Purpose The Exchange proposes to amend Rule 11.18 to exclude all rights and...
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2011-11-30
... Rule Change To Modify Exchange Rule 11.18 Relating to Trading Pauses Due to Extraordinary Market... proposal to amend Rule 11.18, entitled ``Trading Halts Due to Extraordinary Market Volatility.'' The text... Proposed Rule Change 1. Purpose The Exchange proposes to amend Rule 11.18 to exclude all rights and...
ERIC Educational Resources Information Center
Tentama, Fatwa; Pranungsari, Dessy
2016-01-01
Teachers' work motivation and teachers' job satisfaction are the factors influencing the organizational commitment. This research is aimed to empirically examine the roles of teachers' work motivation and teachers' job satisfaction in the commitment of the organization in extraordinary schools. The subjects of the research are the teachers in…
Gao, Weilu; Shu, Jie; Reichel, Kimberly; Nickel, Daniel V; He, Xiaowei; Shi, Gang; Vajtai, Robert; Ajayan, Pulickel M; Kono, Junichiro; Mittleman, Daniel M; Xu, Qianfan
2014-03-12
Gate-controllable transmission of terahertz (THz) radiation makes graphene a promising material for making high-speed THz wave modulators. However, to date, graphene-based THz modulators have exhibited only small on/off ratios due to small THz absorption in single-layer graphene. Here we demonstrate a ∼50% amplitude modulation of THz waves with gated single-layer graphene by the use of extraordinary transmission through metallic ring apertures placed right above the graphene layer. The extraordinary transmission induced ∼7 times near-filed enhancement of THz absorption in graphene. These results promise complementary metal-oxide-semiconductor compatible THz modulators with tailored operation frequencies, large on/off ratios, and high speeds, ideal for applications in THz communications, imaging, and sensing.
Manipulating Acoustic Wavefront by Inhomogeneous Impedance and Steerable Extraordinary Reflection
Zhao, Jiajun; Li, Baowen; Chen, Zhining; Qiu, Cheng-Wei
2013-01-01
We unveil the connection between the acoustic impedance along a flat surface and the reflected acoustic wavefront, in order to empower a wide wariety of novel applications in acoustic community. Our designed flat surface can generate double reflections: the ordinary reflection and the extraordinary one whose wavefront is manipulated by the proposed impedance-governed generalized Snell's law of reflection (IGSL). IGSL is based on Green's function and integral equation, instead of Fermat's principle for optical wavefront manipulation. Remarkably, via the adjustment of the designed specific acoustic impedance, extraordinary reflection can be steered for unprecedented acoustic wavefront while that ordinary reflection can be surprisingly switched on or off. The realization of the complex discontinuity of the impedance surface has been proposed using Helmholtz resonators. PMID:23985717
Babinet's principle in double-refraction systems
NASA Astrophysics Data System (ADS)
Ropars, Guy; Le Floch, Albert
2014-06-01
Babinet's principle applied to systems with double refraction is shown to involve spatial interchanges between the ordinary and extraordinary patterns observed through two complementary screens. As in the case of metamaterials, the extraordinary beam does not follow the Snell-Descartes refraction law, the superposition principle has to be applied simultaneously at two points. Surprisingly, by contrast to the intuitive impression, in the presence of the screen with an opaque region, we observe that the emerging extraordinary photon pattern, which however has undergone a deviation, remains fixed when a natural birefringent crystal is rotated while the ordinary one rotates with the crystal. The twofold application of Babinet's principle implies intensity and polarization interchanges but also spatial and dynamic interchanges which should occur in birefringent metamaterials.
Carter, Alex R; McAvoy, Mark P; Siegel, Joshua S; Hong, Xin; Astafiev, Serguei V; Rengachary, Jennifer; Zinn, Kristi; Metcalf, Nicholas V; Shulman, Gordon L; Corbetta, Maurizio
2017-03-01
Visuospatial attention depends on the integration of multiple processes, and people with right hemisphere lesions after a stroke may exhibit severe or no visuospatial deficits. The anatomy of core components of visuospatial attention is an area of intense interest. Here we examine the relationship between the disruption of core components of attention and lesion distribution in a heterogeneous group (N = 70) of patients with right hemisphere strokes regardless of the presence of clinical neglect. Deficits of lateralized spatial orienting, measured as the difference in reaction times for responding to visual targets in the contralesional or ipsilesional visual field, and deficits in re-orienting attention, as measured by the difference in reaction times for invalidly versus validly cued targets, were measured using a computerized spatial orienting task. Both measures were related through logistic regression and a novel ridge regression method to anatomical damage measured with magnetic resonance imaging. While many regions were common to both deficit maps, a deficit in lateralized spatial orienting was more associated with lesions in the white matter underlying the posterior parietal cortex, and middle and inferior frontal gyri. A deficit in re-orienting of attention toward unattended locations was associated with lesions in the white matter of the posterior parietal cortex, insular cortex and less so with white matter involvement of the anterior frontal lobe. An hodological analysis also supports this partial dissociation between the white matter tracts that are damaged in lateralized spatial biases versus impaired re-orienting. Our results underscore that the integrity of fronto-parietal white matter tracts is crucial for visuospatial attention and that different attention components are mediated by partially distinct neuronal substrates. Copyright © 2016 Elsevier Ltd. All rights reserved.
Ou, X; Andres, A; Pivik, R T; Cleves, M A; Snow, J H; Ding, Z; Badger, T M
2016-04-01
Infant diets may have significant impact on brain development in children. The aim of this study was to evaluate brain gray matter structure and function in 8-year-old children who were predominantly breastfed or fed cow's milk formula as infants. Forty-two healthy children (breastfed: n = 22, 10 boys and 12 girls; cow's milk formula: n = 20, 10 boys and 10 girls) were studied by using structural MR imaging (3D T1-weighted imaging) and blood oxygen level-dependent fMRI (while performing tasks involving visual perception and language functions). They were also administered standardized tests evaluating intelligence (Reynolds Intellectual Assessment Scales) and language skills (Clinical Evaluation of Language Fundamentals). Total brain gray matter volume did not differ between the breastfed and cow's milk formula groups. However, breastfed children had significantly higher (P < .05, corrected) regional gray matter volume measured by voxel-based morphometry in the left inferior temporal lobe and left superior parietal lobe compared with cow's milk formula-fed children. Breastfed children showed significantly more brain activation in the right frontal and left/right temporal lobes on fMRI when processing the perception task and in the left temporal/occipital lobe when processing the visual language task than cow's milk formula-fed children. The imaging findings were associated with significantly better performance for breastfed than cow's milk formula-fed children on both tasks. Our findings indicated greater regional gray matter development and better regional gray matter function in breastfed than cow's milk formula-fed children at 8 years of age and suggested that infant diets may have long-term influences on brain development in children. © 2016 by American Journal of Neuroradiology.
Is orbital volume associated with eyeball and visual cortex volume in humans?
Pearce, Eiluned; Bridge, Holly
2013-01-01
In humans orbital volume increases linearly with absolute latitude. Scaling across mammals between visual system components suggests that these larger orbits should translate into larger eyes and visual cortices in high latitude humans. Larger eyes at high latitudes may be required to maintain adequate visual acuity and enhance visual sensitivity under lower light levels. To test the assumption that orbital volume can accurately index eyeball and visual cortex volumes specifically in humans. Structural Magnetic Resonance Imaging (MRI) techniques are employed to measure eye and orbit (n = 88) and brain and visual cortex (n = 99) volumes in living humans. Facial dimensions and foramen magnum area (a proxy for body mass) were also measured. A significant positive linear relationship was found between (i) orbital and eyeball volumes, (ii) eyeball and visual cortex grey matter volumes and (iii) different visual cortical areas, independently of overall brain volume. In humans the components of the visual system scale from orbit to eye to visual cortex volume independently of overall brain size. These findings indicate that orbit volume can index eye and visual cortex volume in humans, suggesting that larger high latitude orbits do translate into larger visual cortices.
Is orbital volume associated with eyeball and visual cortex volume in humans?
Pearce, Eiluned; Bridge, Holly
2013-01-01
Background In humans orbital volume increases linearly with absolute latitude. Scaling across mammals between visual system components suggests that these larger orbits should translate into larger eyes and visual cortices in high latitude humans. Larger eyes at high latitudes may be required to maintain adequate visual acuity and enhance visual sensitivity under lower light levels. Aim To test the assumption that orbital volume can accurately index eyeball and visual cortex volumes specifically in humans. Subjects & Methods Structural Magnetic Resonance Imaging (MRI) techniques are employed to measure eye and orbit (N=88), and brain and visual cortex (N=99) volumes in living humans. Facial dimensions and foramen magnum area (a proxy for body mass) were also measured. Results A significant positive linear relationship was found between (i) orbital and eyeball volumes, (ii) eyeball and visual cortex grey matter volumes, (iii) different visual cortical areas, independently of overall brain volume. Conclusion In humans the components of the visual system scale from orbit to eye to visual cortex volume independently of overall brain size. These findings indicate that orbit volume can index eye and visual cortex volume in humans, suggesting that larger high latitude orbits do translate into larger visual cortices. PMID:23879766
NASA Astrophysics Data System (ADS)
Kemp, Martin
1998-08-01
If matter fills the Universe, making everything happen by its interactions, what does it all look like? René Descartes may have been over-mechanistic in his view, but his efforts to visualize the invisible created striking images.
PLANETarium - Visualizing Earth Sciences in the Planetarium
NASA Astrophysics Data System (ADS)
Ballmer, M. D.; Wiethoff, T.; Kraupe, T. W.
2013-12-01
In the past decade, projection systems in most planetariums, traditional sites of outreach and public education, have advanced from instruments that can visualize the motion of stars as beam spots moving over spherical projection areas to systems that are able to display multicolor, high-resolution, immersive full-dome videos or images. These extraordinary capabilities are ideally suited for visualization of global processes occurring on the surface and within the interior of the Earth, a spherical body just as the full dome. So far, however, our community has largely ignored this wonderful interface for outreach and education. A few documentaries on e.g. climate change or volcanic eruptions have been brought to planetariums, but are taking little advantage of the true potential of the medium, as mostly based on standard two-dimensional videos and cartoon-style animations. Along these lines, we here propose a framework to convey recent scientific results on the origin and evolution of our PLANET to the >100,000,000 per-year worldwide audience of planetariums, making the traditionally astronomy-focussed interface a true PLANETarium. In order to do this most efficiently, we intend to directly show visualizations of scientific datasets or models, originally designed for basic research. Such visualizations in solid-Earth, as well as athmospheric and ocean sciences, are expected to be renderable to the dome with little or no effort. For example, showing global geophysical datasets (e.g., surface temperature, gravity, magnetic field), or horizontal slices of seismic-tomography images and of spherical computer simulations (e.g., climate evolution, mantle flow or ocean currents) requires almost no rendering at all. Three-dimensional Cartesian datasets or models can be rendered using standard methods. With the appropriate audio support, present-day science visualizations are typically as intuitive as cartoon-style animations, yet more appealing visually, and clearly more informative as revealing the complexity and beauty of our planet. In addition to e.g. climate change and natural hazards, themes of interest may include the coupled evolution of the Earth's interior and life, from the accretion of our planet to the generation and sustainment of the magnetic field as well as of habitable conditions in the atmosphere and oceans. We believe that high-quality tax-funded science visualizations should not exclusively be used to facilitate communication amoung scientists, but also be directly recycled to raise the public's awareness and appreciation of geosciences.
Visual analytics for aviation safety: A collaborative approach to sensemaking
NASA Astrophysics Data System (ADS)
Wade, Andrew
Visual analytics, the "science of analytical reasoning facilitated by interactive visual interfaces", is more than just visualization. Understanding the human reasoning process is essential for designing effective visualization tools and providing correct analyses. This thesis describes the evolution, application and evaluation of a new method for studying analytical reasoning that we have labeled paired analysis. Paired analysis combines subject matter experts (SMEs) and tool experts (TE) in an analytic dyad, here used to investigate aircraft maintenance and safety data. The method was developed and evaluated using interviews, pilot studies and analytic sessions during an internship at the Boeing Company. By enabling a collaborative approach to sensemaking that can be captured by researchers, paired analysis yielded rich data on human analytical reasoning that can be used to support analytic tool development and analyst training. Keywords: visual analytics, paired analysis, sensemaking, boeing, collaborative analysis.
Tisdall, Laura
2016-12-01
A sudden influx of portrayals of 'extraordinary children' emerged in British science fiction after the Second World War. Such children both violated and confirmed the new set of expectations about ordinary childhood that emerged from the findings of developmental psychologists around the same time. Previous work on extraordinary children in both science fiction and horror has tended to confine the phenomenon to an 'evil child boom' within the American filmmaking industry in the 1970s. This article suggests that a much earlier trend is visible in British postwar science fiction texts, analysing a cluster of novels that emerged in the 1950s: Arthur C. Clarke's Childhood's End (1953), William Golding's Lord of the Flies (1954) and John Wyndham's The Midwich Cuckoos (1957). It will be argued that the groups of extraordinary children in these novels both tap into newer child-centred assertions about the threats posed by abnormal childhood, underwritten by psychology and psychoanalysis, and represent a reaction to an older progressive tradition in which children were envisaged as the single hope for a utopian future. This article will ultimately assert that the sudden appearance of extraordinary children in science fiction reflects a profound shift in assessment criteria for healthy childhood in Britain from the 1950s onwards, an issue that had become vitally important in a fledgling social democracy. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.
Code of Federal Regulations, 2013 CFR
2013-01-01
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... pause trading during periods of extraordinary market volatility in S&P 500 stocks.\\3\\ The rules require... extraordinary market volatility, if adopted, applies.\\7\\ On June 23, 2011, the Commission approved the expansion... volatility, and further extended the pilot period, so that the pilot would expire on January 31, 2012.\\9\\ On...
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2011-04-13
... Market Volatility, To Extend the Effective Date of the Pilot Until the Earlier of August 11, 2011 or the Date on Which a Limit Up/Limit Down Mechanism To Address Extraordinary Market Volatility, if Adopted... extraordinary market volatility, to extend the effective date of the pilot by which such rule operates from the...
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... All Stocks Due to Extraordinary Market Volatility September 28, 2011. Pursuant to Section 19(b)(1) of... determining when trading in all stocks will be halted due to extraordinary market volatility. The text of the... volatility. The Exchange is proposing this rule change in consultation with other equity, options and futures...
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..., 2011 or the date on which a limit up/limit down mechanism to address extraordinary market volatility..., 2011 or the date on which a limit up/limit down mechanism to address extraordinary market volatility... volatility in S&P 500 stocks.\\3\\ The rules require the Listing Markets \\4\\ to issue five-minute trading...
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2011-04-12
... Volatility, To Extend the Effective Date of the Pilot Until the Earlier of August 11, 2011 or the Date on Which a Limit Up/Limit Down Mechanism To Address Extraordinary Market Volatility, If Adopted, Applies... due to extraordinary market volatility, to extend the effective date of the pilot by which such rule...
'This chimp will kick your ass at memory games - but how the hell does he do it?'.
Humphrey, Nicholas
2012-07-01
Extraordinary evidence generates extraordinary claims. I discuss the remarkable memory skills of chimpanzees tested in the Kyoto Primate Laboratory, and suggest a novel – but deflationary – hypothesis to explain them. Could the chimpanzees, who have been highly trained to learn the sequence of Arabic numerals, have developed number–colour synaesthesia?
Pettit, Lewis D; Bastin, Mark E; Smith, Colin; Bak, Thomas H; Gillingwater, Thomas H; Abrahams, Sharon
2013-11-01
Cognitive impairment in amyotrophic lateral sclerosis is characterized by deficits on tests of executive function; however, the contribution of abnormal processing speed is unknown. Methods are confounded by tasks that depend on motor speed in patients with physical disability. Structural and functional magnetic resonance imaging studies have revealed multi-system cerebral involvement, with evidence of reduced white matter volume and integrity in predominant frontotemporal regions. The current study has two aims. First, to investigate whether cognitive impairments in amyotrophic lateral sclerosis are due to executive dysfunction or slowed processing speed using methodology that accommodates motor disability. This is achieved using a dual-task paradigm and tasks that manipulate stimulus presentation times and do not rely on response motor speed. Second, to identify relationships between specific cognitive impairments and the integrity of distinct white matter tracts. Thirty patients with amyotrophic lateral sclerosis and 30 age- and education-matched control subjects were administered an experimental dual-task procedure that combined a visual inspection time task and digit recall. In addition, measures of executive function (including letter fluency) and processing speed (visual inspection time and rapid serial letter identification) were administered. Integrity of white matter tracts was determined using region of interest analyses of diffusion tensor magnetic resonance imaging data. Patients with amyotrophic lateral sclerosis did not show impairments on tests of processing speed, but executive deficits were revealed once visual inspection time was combined with digit recall (dual-task) and in letter fluency. In addition to the corticospinal tracts, significant differences in fractional anisotropy and mean diffusivity were found between groups in a number of prefrontal and temporal white matter tracts including the anterior cingulate, anterior thalamic radiation, uncinate fasciculus and hippocampal portion of the cingulum bundles. Significant differences also emerged in the anterior corona radiata as well as in white matter underlying the superior, medial and inferior frontal gyri and the temporal gyri. Dual-task performance significantly correlated with fractional anisotropy measures in the middle frontal gyrus white matter and anterior corona radiata. Letter fluency indices significantly correlated with fractional anisotropy measures of the inferior frontal gyrus white matter and corpus callosum in addition to the corticospinal tracts and mean diffusivity measures in the white matter of the superior frontal gyrus. The current study demonstrates that cognitive impairment in amyotrophic lateral sclerosis is not due to generic slowing of processing speed. Moreover, different executive deficits are related to distinct prefrontal tract involvement in amyotrophic lateral sclerosis with dual-task impairment associating with dorsolateral prefrontal dysfunction and letter fluency showing greater dependence on inferolateral prefrontal dysfunction.
Gawryluk, Jodie R.; Mazerolle, Erin L.; D'Arcy, Ryan C. N.
2014-01-01
Functional magnetic resonance imaging (fMRI) is a non-invasive technique that allows for visualization of activated brain regions. Until recently, fMRI studies have focused on gray matter. There are two main reasons white matter fMRI remains controversial: (1) the blood oxygen level dependent (BOLD) fMRI signal depends on cerebral blood flow and volume, which are lower in white matter than gray matter and (2) fMRI signal has been associated with post-synaptic potentials (mainly localized in gray matter) as opposed to action potentials (the primary type of neural activity in white matter). Despite these observations, there is no direct evidence against measuring fMRI activation in white matter and reports of fMRI activation in white matter continue to increase. The questions underlying white matter fMRI activation are important. White matter fMRI activation has the potential to greatly expand the breadth of brain connectivity research, as well as improve the assessment and diagnosis of white matter and connectivity disorders. The current review provides an overview of the motivation to investigate white matter fMRI activation, as well as the published evidence of this phenomenon. We speculate on possible neurophysiologic bases of white matter fMRI signals, and discuss potential explanations for why reports of white matter fMRI activation are relatively scarce. We end with a discussion of future basic and clinical research directions in the study of white matter fMRI. PMID:25152709
Visual Disturbances: Related to Migraine or Not?
... warrants medical attention. Causes for concern include: New dark spots or floaters in one eye (remember, cover ... Chairman of the American Migraine Foundation. “To make matters worse, women with migraine are at a significantly ...
NASA Astrophysics Data System (ADS)
Tice, Michael M.; Lowe, Donald R.
2006-06-01
The geological record of carbonaceous matter from at least 3.5 Ga to the end of the Precambrian is fundamentally continuous in terms of carbonaceous matter structure, composition, environments of deposition/preservation, and abundance in host rocks. No abiotic processes are currently known to be capable of producing continuity in all four of these properties. Although this broad view of the geological record does not prove that life had arisen by 3.5 Ga, the end of the early Archean, it suggests a working hypothesis: most if not all carbonaceous matter present in rocks older than 3.0 Ga was produced by living organisms. This hypothesis must be tested by studies of specific early geological units designed to explore the form, distribution, and origin of enclosed carbonaceous matter. The carbonaceous, environmentally diverse 3416 Ma Buck Reef Chert (BRC) of the Barberton greenstone belt, South Africa, provides an opportunity for such a study. Upward facies progressions in the BRC reflect deposition in environments ranging from shallow marine evaporitic brine ponds to a storm- and wave-active shelf to a deep, low-energy basinal setting below storm wave base. Abundances and ratios of Al 2O 3, Zr, TiO 2, and Cr track inputs of various types of volcaniclastic and terrigenous clastic materials. In particular, Zr/Al 2O 3 and Zr serve as proxies for concentration of windblown dust and, indirectly, as proxies for sedimentation rate. Cu, Zn, Ni, and FeO were concentrated in the most slowly deposited transitional and basinal sediments, inconsistent with a hydrothermal setting but consistent with a normal marine setting. The distribution of microfacies defined by associations and layering of clastic, ferruginous, and carbonaceous grains correlates with facies transitions. Fine carbonaceous laminations, which occur only in shallow platform settings, represent photosynthetic microbial mats. These were ripped up and the debris widely redistributed in shallow and deep water by waves and storms. The isotopic composition of carbonaceous matter ranges from - 35‰ to - 30‰ in shallow-water settings and to - 20‰ in deep-water units. The heavier δ13C in deep-water carbonaceous matter is thought to reflect microbial processing, possibly by fermentation and methanogenesis, of organic matter originally produced in shallow water. Hydrothermal origins for BRC carbonaceous matter are clearly excluded by the inferred depositional setting of the rocks as a whole, an inference supported by field, petrographic, and geochemical analysis. We suggest that the biological model proposed here for BRC carbonaceous matter is the best currently available. The hypothesis that "at least some carbonaceous matter present in rocks older than 3.0 Ga was produced by living organisms" should be regarded as likely until extraordinary contradictory evidence is presented.
White matter lesion extension to automatic brain tissue segmentation on MRI.
de Boer, Renske; Vrooman, Henri A; van der Lijn, Fedde; Vernooij, Meike W; Ikram, M Arfan; van der Lugt, Aad; Breteler, Monique M B; Niessen, Wiro J
2009-05-01
A fully automated brain tissue segmentation method is optimized and extended with white matter lesion segmentation. Cerebrospinal fluid (CSF), gray matter (GM) and white matter (WM) are segmented by an atlas-based k-nearest neighbor classifier on multi-modal magnetic resonance imaging data. This classifier is trained by registering brain atlases to the subject. The resulting GM segmentation is used to automatically find a white matter lesion (WML) threshold in a fluid-attenuated inversion recovery scan. False positive lesions are removed by ensuring that the lesions are within the white matter. The method was visually validated on a set of 209 subjects. No segmentation errors were found in 98% of the brain tissue segmentations and 97% of the WML segmentations. A quantitative evaluation using manual segmentations was performed on a subset of 6 subjects for CSF, GM and WM segmentation and an additional 14 for the WML segmentations. The results indicated that the automatic segmentation accuracy is close to the interobserver variability of manual segmentations.
Omizzolo, Cristina; Scratch, Shannon E; Stargatt, Robyn; Kidokoro, Hiroyuki; Thompson, Deanne K; Lee, Katherine J; Cheong, Jeanie; Neil, Jeffrey; Inder, Terrie E; Doyle, Lex W; Anderson, Peter J
2014-01-01
Using prospective longitudinal data from 198 very preterm and 70 full term children, this study characterised the memory and learning abilities of very preterm children at 7 years of age in both verbal and visual domains. The relationship between the extent of brain abnormalities on neonatal magnetic resonance imaging (MRI) and memory and learning outcomes at 7 years of age in very preterm children was also investigated. Neonatal MRI scans were qualitatively assessed for global, white-matter, cortical grey-matter, deep grey-matter, and cerebellar abnormalities. Very preterm children performed less well on measures of immediate memory, working memory, long-term memory, and learning compared with term born controls. Neonatal brain abnormalities, and in particular deep grey matter abnormality, were associated with poorer memory and learning performance at 7 years in very preterm children, especially global, white-matter, grey-matter and cerebellar abnormalities. Findings support the importance of cerebral neonatal pathology for predicting later memory and learning function. PMID:23805915
Dormal, Giulia; Lepore, Franco; Harissi-Dagher, Mona; Albouy, Geneviève; Bertone, Armando; Rossion, Bruno
2014-01-01
Visual deprivation leads to massive reorganization in both the structure and function of the occipital cortex, raising crucial challenges for sight restoration. We tracked the behavioral, structural, and neurofunctional changes occurring in an early and severely visually impaired patient before and 1.5 and 7 mo after sight restoration with magnetic resonance imaging. Robust presurgical auditory responses were found in occipital cortex despite residual preoperative vision. In primary visual cortex, crossmodal auditory responses overlapped with visual responses and remained elevated even 7 mo after surgery. However, these crossmodal responses decreased in extrastriate occipital regions after surgery, together with improved behavioral vision and with increases in both gray matter density and neural activation in low-level visual regions. Selective responses in high-level visual regions involved in motion and face processing were observable even before surgery and did not evolve after surgery. Taken together, these findings demonstrate that structural and functional reorganization of occipital regions are present in an individual with a long-standing history of severe visual impairment and that such reorganizations can be partially reversed by visual restoration in adulthood. PMID:25520432
Using Visualization Science to Evaluate Effective Communication of Climate Indicators
NASA Astrophysics Data System (ADS)
Gerst, M.; Kenney, M. A.; Wolfinger, F.; Lloyd, A.
2015-12-01
Indicators are observations or calculations that are used to track social and environmental conditions over time. For a large coupled system such as the economy and environment, the choice of indicators requires a structured process that involves co-production among facilitators, subject-matter experts, decision-makers, and the general public. This co-production is needed in part because such indicators serve a duel role of scientifically tracking change and of communicating to non-scientists important changes and information that may be useful in decision contexts. Because the goal is to communicate and inform decisions it is critical that indicators be understood by non-scientific audiences, which may require different visualization techniques than for scientific audiences. Here we describe a process of rigorously evaluating visual communication efficacy by using a simplified taxonomy of visualization design problems and trade-offs to assess existing and redesigned indicator images. The experimental design is three-part. It involves testing non-scientific audiences' understandability of scientific images found in the literature along with similar information shaped by a partial co-production process that informed the U.S. Global Change Research Program prototype indicators system, released in Spring 2015. These recommendations for physical, natural, and societal indicators of changes and impacts involved input from over 200 subject-matter experts, organized into 13 technical teams. Using results from the first two parts, we then explore visualization design improvements that may increase understandability to non-scientific audiences. We anticipate that this work will highlight important trade-offs in visualization design when moving between audiences that will be of great use to scientists who wish to communicate their results broader audiences.
Light and dark matter in the universe
DOE Office of Scientific and Technical Information (OSTI.GOV)
None
This simulation follows the growth of density perturbations in both gas and dark matter components in a volume 1 billion light years on a side beginning shortly after the Big Bang and evolved to half the present age of the universe. It calculates the gravitational clumping of intergalactic gas and dark matter modeled using a computational grid of 64 billion cells and 64 billion dark matter particles. The simulation uses a computational grid of 4096^3 cells and took over 4,000,000 CPU hours to complete. Read more: http://www.anl.gov/Media_Center/News/2010/news100104.html. Credits: Science: Michael L. Norman, Robert Harkness, Pascal Paschos and Rick Wagner Visualization:more » Mark Herald, Joseph A. Insley, Eric C. Olson and Michael E. Papka« less
Bogousslavsky, J; Miklossy, J; Deruaz, J P; Assal, G; Regli, F
1987-01-01
A macular-sparing superior altitudinal hemianopia with no visuo-psychic disturbance, except impaired visual learning, was associated with bilateral ischaemic necrosis of the lingual gyrus and only partial involvement of the fusiform gyrus on the left side. It is suggested that bilateral destruction of the lingual gyrus alone is not sufficient to affect complex visual processing. The fusiform gyrus probably has a critical role in colour integration, visuo-spatial processing, facial recognition and corresponding visual imagery. Involvement of the occipitotemporal projection system deep to the lingual gyri probably explained visual memory dysfunction, by a visuo-limbic disconnection. Impaired verbal memory may have been due to posterior involvement of the parahippocampal gyrus and underlying white matter, which may have disconnected the intact speech areas from the left medial temporal structures. Images PMID:3585386
NASA Astrophysics Data System (ADS)
Cid, Ximena; Lopez, Ramon
2011-10-01
It is well known that student have difficulties with concepts in physics and space science as well as other STEM fields. Some of these difficulties may be rooted in student conceptual errors, whereas other difficulties may arise from issues with visual cognition and spatial intelligence. It has also been suggested that some aspects of high attrition rates from STEM fields can be attributed to students' visual spatial abilities. We will be presenting data collected from introductory courses in the College of Engineering, Department of Physics, Department of Chemistry, and the Department of Mathematics at the University of Texas at Arlington. These data examine the relationship between students' visual spatial abilities and comprehension in the subject matter. Where correlations are found to exist, visual spatial interventions can be implemented to reduce the attrition rates.
Neural Anatomy of Primary Visual Cortex Limits Visual Working Memory.
Bergmann, Johanna; Genç, Erhan; Kohler, Axel; Singer, Wolf; Pearson, Joel
2016-01-01
Despite the immense processing power of the human brain, working memory storage is severely limited, and the neuroanatomical basis of these limitations has remained elusive. Here, we show that the stable storage limits of visual working memory for over 9 s are bound by the precise gray matter volume of primary visual cortex (V1), defined by fMRI retinotopic mapping. Individuals with a bigger V1 tended to have greater visual working memory storage. This relationship was present independently for both surface size and thickness of V1 but absent in V2, V3 and for non-visual working memory measures. Additional whole-brain analyses confirmed the specificity of the relationship to V1. Our findings indicate that the size of primary visual cortex plays a critical role in limiting what we can hold in mind, acting like a gatekeeper in constraining the richness of working mental function. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.
Wang, Sheng-Wen; Medina, Henry; Hong, Kuo-Bin; Wu, Chun-Chia; Qu, Yindong; Manikandan, Arumugam; Su, Teng-Yu; Lee, Po-Tsung; Huang, Zhi-Quan; Wang, Zhiming; Chuang, Feng-Chuan; Kuo, Hao-Chung; Chueh, Yu-Lun
2017-09-26
Integration of strain engineering of two-dimensional (2D) materials in order to enhance device performance is still a challenge. Here, we successfully demonstrated the thermally strained band gap engineering of transition-metal dichalcogenide bilayers by different thermal expansion coefficients between 2D materials and patterned sapphire structures, where MoS 2 bilayers were chosen as the demonstrated materials. In particular, a blue shift in the band gap of the MoS 2 bilayers can be tunable, displaying an extraordinary capability to drive electrons toward the electrode under the smaller driven bias, and the results were confirmed by simulation. A model to explain the thermal strain in the MoS 2 bilayers during the synthesis was proposed, which enables us to precisely predict the band gap-shifted behaviors on patterned sapphire structures with different angles. Furthermore, photodetectors with enhancement of 286% and 897% based on the strained MoS 2 on cone- and pyramid-patterned sapphire substrates were demonstrated, respectively.
Massive isotopic effect in vacuum UV photodissociation of N2 and implications for meteorite data
Chakraborty, Subrata; Muskatel, B. H.; Jackson, Teresa L.; Ahmed, Musahid; Levine, R. D.; Thiemens, Mark H.
2014-01-01
Nitrogen isotopic distributions in the solar system extend across an enormous range, from −400‰, in the solar wind and Jovian atmosphere, to about 5,000‰ in organic matter in carbonaceous chondrites. Distributions such as these require complex processing of nitrogen reservoirs and extraordinary isotope effects. While theoretical models invoke ion-neutral exchange reactions outside the protoplanetary disk and photochemical self-shielding on the disk surface to explain the variations, there are no experiments to substantiate these models. Experimental results of N2 photolysis at vacuum UV wavelengths in the presence of hydrogen are presented here, which show a wide range of enriched δ15N values from 648‰ to 13,412‰ in product NH3, depending upon photodissociation wavelength. The measured enrichment range in photodissociation of N2, plausibly explains the range of δ15N in extraterrestrial materials. This study suggests the importance of photochemical processing of the nitrogen reservoirs within the solar nebula. PMID:25267643
The Arabidopsis thaliana aquaporin AtPIP1;2 is a physiologically relevant CO₂ transport facilitator.
Heckwolf, Marlies; Pater, Dianne; Hanson, David T; Kaldenhoff, Ralf
2011-09-01
Cellular exchange of carbon dioxide (CO₂) is of extraordinary importance for life. Despite this significance, its molecular mechanisms are still unclear and a matter of controversy. In contrast to other living organisms, plants are physiologically limited by the availability of CO₂. In most plants, net photosynthesis is directly dependent on CO₂ diffusion from the atmosphere to the chloroplast. Thus, it is important to analyze CO₂ transport with regards to its effect on photosynthesis. A mutation of the Arabidopsis thaliana AtPIP1;2 gene, which was characterized as a non-water transporting but CO₂ transport-facilitating aquaporin in heterologous expression systems, correlated with a reduction in photosynthesis under a wide range of atmospheric CO₂ concentrations. Here, we could demonstrate that the effect was caused by reduced CO₂ conductivity in leaf tissue. It is concluded that the AtPIP1;2 gene product limits CO₂ diffusion and photosynthesis in leaves. © 2011 The Authors. The Plant Journal © 2011 Blackwell Publishing Ltd.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Nürnberger, P.; Reinhardt, H.; Kim, H-C.
2015-10-07
The research in this paper deals with the angular dependence of the formation of laser-induced periodic surface structures (LIPSS) by linearly polarized nanosecond laser pulses on polycrystalline austenitic stainless steel. Incident angles ranging from 45° to 70° lead to the generation of superimposed merely perpendicular oriented LIPSS on steel as well as on monocrystalline (100) silicon which was used as a reference material. Additional extraordinary orientations of superimposing LIPSS along with significantly different periodicities are found on polycrystalline steel but not on (100) silicon. Electron backscatter diffraction measurements indicate that the expansion of these LIPSS is limited to the grainmore » size and affected by the crystal orientation of the individual grains. Atomic force microscopy imaging shows that LIPSS fringe heights are in good agreement with the theoretically predicted penetration depths of surface plasmon polaritons into stainless steel. These results indicate that optical anisotropies must be taken into account to fully describe the theory of light-matter interaction leading to LIPSS formation.« less
Fan, Yuancheng; Qiao, Tong; Zhang, Fuli; Fu, Quanhong; Dong, Jiajia; Kong, Botao; Li, Hongqiang
2017-01-16
Electromagnetically induced transparency (EIT) is a promising technology for the enhancement of light-matter interactions, and recent demonstrations of the EIT analogue realized in artificial micro-structured medium have remarkably reduced the extreme requirement for experimental observation of EIT spectrum. In this paper, we propose to electrically control the EIT-like spectrum in a metamaterial as an electromagnetic modulator. A diode acting as a tunable resistor is loaded in the gap of paired wires to inductively tune the magnetic resonance, which induces remarkable modulation on the EIT-like spectrum through the metamaterial sample. The experimental measurements confirmed that the prediction of electromagnetic modulation in three narrow bands on the EIT-like spectrum, and a modulation contrast of up to 31 dB was achieved on the transmission through the metamaterial. Our results may facilitate the study on active/dynamical technology in translational metamaterials, which connect extraordinary manipulations on the flow of light in metamaterials, e.g., the exotic EIT, and practical applications in industry.
Robert J. Genco: Pioneer in Oral Science Advancement.
Taubman, M A
2018-07-01
Professor Robert J. Genco made extraordinary research advances in immunology, periodontology, and microbiology research, pioneering major advances in oral science. In addition to his extraordinary research advancements in oral biology, his pioneering advances in oral science leadership at the local/university, national, and international levels are recognized worldwide, as are his educational advancements. In his era, he is truly the "father" of oral science.
ERIC Educational Resources Information Center
Mitrani, Judith L.
Many people come to analysis appearing quite ordinary on the surface. However, once below that surface, there often appear extraordinary protections created to keep at bay any awareness of deeply traumatic happenings occurring at some point in life. This book investigates the development and function of these protections, allowing the reader to…
Theoretical Comparison Between Candidates for Dark Matter
NASA Astrophysics Data System (ADS)
McKeough, James; Hira, Ajit; Valdez, Alexandra
2017-01-01
Since the generally-accepted view among astrophysicists is that the matter component of the universe is mostly dark matter, the search for dark matter particles continues unabated. The Large Underground Xenon (LUX) improvements, aided by advanced computer simulations at the U.S. Department of Energy's Lawrence Berkeley National Laboratory's (Berkeley Lab) National Energy Research Scientific Computing Center (NERSC) and Brown University's Center for Computation and Visualization (CCV), can potentially eliminate some particle models of dark matter. Generally, the proposed candidates can be put in three categories: baryonic dark matter, hot dark matter, and cold dark matter. The Lightest Supersymmetric Particle(LSP) of supersymmetric models is a dark matter candidate, and is classified as a Weakly Interacting Massive Particle (WIMP). Similar to the cosmic microwave background radiation left over from the Big Bang, there is a background of low-energy neutrinos in our Universe. According to some researchers, these may be the explanation for the dark matter. One advantage of the Neutrino Model is that they are known to exist. Dark matter made from neutrinos is termed ``hot dark matter''. We formulate a novel empirical function for the average density profile of cosmic voids, identified via the watershed technique in ΛCDM N-body simulations. This function adequately treats both void size and redshift, and describes the scale radius and the central density of voids. We started with a five-parameter model. Our research is mainly on LSP and Neutrino models.
Li, Qian; Zhai, Liying; Jiang, Qinying; Qin, Wen; Li, Qingji; Yin, Xiaohui; Guo, Mingxia
2015-06-15
Amblyopia is a neurological disorder of vision that follows abnormal binocular interaction or visual deprivation during early life. Previous studies have reported multiple functional or structural cortical alterations. Although white matter was also studied, it still cannot be clarified clearly which fasciculus was affected by amblyopia. In the present study, tract-based spatial statistics analysis was applied to diffusion tensor imaging (DTI) to investigate potential diffusion changes of neural tracts in anisometropic amblyopia. Fractional anisotropy (FA) value was calculated and compared between 20 amblyopic children and 18 healthy age-matched controls. In contrast to the controls, significant decreases in FA values were found in right optic radiation (OR), left inferior longitudinal fasciculus/inferior fronto-occipital fasciculus (ILF/IFO) and right superior longitudinal fasciculus (SLF) in the amblyopia. Furthermore, FA values of these identified tracts showed positive correlation with visual acuity. It can be inferred that abnormal visual input not only hinders OR from well developed, but also impairs fasciculi associated with dorsal and ventral visual pathways, which may be responsible for the amblyopic deficiency in object discrimination and stereopsis. Increased FA was detected in right posterior part of corpus callosum (CC) with a medium effect size, which may be due to compensation effect. DTI with subsequent measurement of FA is a useful tool for investigating neuronal tract involvement in amblyopia. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.
Tiehuis, A M; Vincken, K L; Mali, W P T M; Kappelle, L J; Anbeek, P; Algra, A; Biessels, G J
2008-01-01
A reliable scoring method for ischemic cerebral white matter hyperintensities (WMH) will help to clarify the causes and consequences of these brain lesions. We compared an automated and two visual WMH scoring methods in their relations with age and cognitive function. MRI of the brain was performed on 154 participants of the Utrecht Diabetic Encephalopathy Study. WMH volumes were obtained with an automated segmentation method. Visual rating of deep and periventricular WMH (DWMH and PWMH) was performed with the Scheltens scale and the Rotterdam Scan Study (RSS) scale, respectively. Cognition was assessed with a battery of 11 tests. Within the whole study group, the association with age was most evident for the automated measured WMH volume (beta = 0.43, 95% CI = 0.29-0.57). With regard to cognition, automated measured WMH volume and Scheltens DWMH were significantly associated with information processing speed (beta = -0.22, 95% CI = -0.40 to -0.06; beta = -0.26, 95% CI = -0.42 to -0.10), whereas RSS PWMH were associated with attention and executive function (beta = -0.19, 95% CI = -0.36 to -0.02). Measurements of WMH with an automated quantitative segmentation method are comparable with visual rating scales and highly suitable for use in future studies to assess the relationship between WMH and subtle impairments in cognitive function. (c) 2007 S. Karger AG, Basel.
Tai Chi Chuan and Baduanjin increase grey matter volume in older adults: a brain imaging study
Tao, Jing; Liu, Jiao; Liu, Weilin; Huang, Jia; Xue, Xiehua; Chen, Xiangli; Wu, Jinsong; Zheng, Guohua; Chen, Bai; Li, Ming; Sun, Sharon; Jorgenson, Kristen; Lang, Courtney; Hu, Kun; Chen, Shanjia; Chen, Lidian; Kong, Jian
2017-01-01
The aim of this study is to investigate and compare how 12-weeks of Tai Chi Chuan and Baduanjin exercise can modulate brain structure and memory function in older adults. Magnetic Resonance Imaging(MRI) and memory function measurements (Wechsler Memory Scale-Chinese revised, WMS-CR)were applied at both the beginning and end of the study. Results showed that both Tai Chi Chuan and Baduanjin could significantly increase grey matter volume (GMV) in the insula, medial temporal lobe (MTL), and putamen after 12-weeks of exercise. No significant differences were observed in grey matter volume (GMV) between the Tai Chi Chuan and Baduanjin groups. We also found that compared to healthy controls, Tai Chi Chuan and Baduanjin significantly improved visual reproduction subscores on the WMS-CR. Baduanjin also improved mental control, recognition, touch and comprehension memory subscores of the WMS-CR compared to the control group. Memory quotient (MQ)and visual reproduction subscores were both associated with GMV increases in the putamen and hippocampus. Our results demonstrate the potential of Tai Chi Chuan and Baduanjin exercise for the prevention of memory deficits in older adults. PMID:28869478
ERIC Educational Resources Information Center
Sartorius, Tara Cady
2002-01-01
Provides background information on the life and career of artist Faith Ringgold. Focuses on her work of art "Under a Blood Red Sky" and includes information on its subject matter. Includes lessons in visual arts, social studies, language arts, and music. (CMK)
NASA Astrophysics Data System (ADS)
Shi, Yunzhou; Zhang, Delong; Huff, Terry B.; Wang, Xiaofei; Shi, Riyi; Xu, Xiao-Ming; Cheng, Ji-Xin
2011-10-01
In vivo imaging of white matter is important for the mechanistic understanding of demyelination and evaluation of remyelination therapies. Although white matter can be visualized by a strong coherent anti-Stokes Raman scattering (CARS) signal from axonal myelin, in vivo repetitive CARS imaging of the spinal cord remains a challenge due to complexities induced by the laminectomy surgery. We present a careful experimental design that enabled longitudinal CARS imaging of de- and remyelination at single axon level in live rats. In vivo CARS imaging of secretory phospholipase A2 induced myelin vesiculation, macrophage uptake of myelin debris, and spontaneous remyelination by Schwann cells are sequentially monitored over a 3 week period. Longitudinal visualization of de- and remyelination at a single axon level provides a novel platform for rational design of therapies aimed at promoting myelin plasticity and repair.
NASA Astrophysics Data System (ADS)
Li, Ting; Gong, Hui; Luo, Qingming
2011-04-01
Using the visible Chinese human data set, which faithfully represents human anatomy, we visualize the light propagation in the head in detail based on Monte Carlo simulation. The simulation is verified to agree with published experimental results in terms of a differential path-length factor. The spatial sensitivity profile turns out to seem like a fat tropical fish with strong distortion along the folding cerebral surface. The sensitive brain region covers the gray matter and extends to the superficial white matter, leading to a large penetration depth (>3 cm). Finally, the optimal source-detector separation is suggested to be narrowed down to 3-3.5 cm, while the sensitivity of the detected signal to brain activation reaches the peak of 8%. These results indicate that the cerebral cortex folding geometry actually has substantial effects on light propagation, which should be necessarily considered for applications of functional near-infrared spectroscopy.
Krieger, N; Dorling, D; McCartney, G
2012-03-01
This symposia discussed "Mapping injustice, visualizing equity: why theory, metaphors and images matter in tackling inequalities". It sought to provoke critical thinking about the current theories used to analyze the health impact of injustice, variously referred to as "health inequalities" in the UK, "social inequalities in health" in the US, and "health inequities" more globally. Our focus was the types of explanations, images, and metaphors these theories employ. Building on frameworks that emphasize politics, agency, and accountability, we suggested that it was essential to engage the general public in the politics of health inequities if progress is to be made. We showcased some examples of such engagement before inviting the audience to consider how this might apply in their own areas of responsibility. Copyright © 2012 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.
Vection and visually induced motion sickness: how are they related?
Keshavarz, Behrang; Riecke, Bernhard E.; Hettinger, Lawrence J.; Campos, Jennifer L.
2015-01-01
The occurrence of visually induced motion sickness has been frequently linked to the sensation of illusory self-motion (vection), however, the precise nature of this relationship is still not fully understood. To date, it is still a matter of debate as to whether vection is a necessary prerequisite for visually induced motion sickness (VIMS). That is, can there be VIMS without any sensation of self-motion? In this paper, we will describe the possible nature of this relationship, review the literature that addresses this relationship (including theoretical accounts of vection and VIMS), and offer suggestions with respect to operationally defining and reporting these phenomena in future. PMID:25941509
Latini, Francesco; Hjortberg, Mats; Aldskogius, Håkan; Ryttlefors, Mats
2015-01-01
The clinical evidences of variable epileptic propagation in occipital lobe epilepsy (OLE) have been demonstrated by several studies. However the exact localization of the epileptic focus sometimes represents a problem because of the rapid propagation to frontal, parietal, or temporal regions. Each white matter pathway close to the supposed initial focus can lead the propagation towards a specific direction, explaining the variable semiology of these rare epilepsy syndromes. Some new insights in occipital white matter anatomy are herein described by means of white matter dissection and compared to the classical epileptic patterns, mostly based on the central position of the primary visual cortex. The dissections showed a complex white matter architecture composed by vertical and longitudinal bundles, which are closely interconnected and segregated and are able to support specific high order functions with parallel bidirectional propagation of the electric signal. The same sublobar lesions may hyperactivate different white matter bundles reemphasizing the importance of the ictal semiology as a specific clinical demonstration of the subcortical networks recruited. Merging semiology, white matter anatomy, and electrophysiology may lead us to a better understanding of these complex syndromes and tailored therapeutic options based on individual white matter connectivity. PMID:26063964
Ordinary and extraordinary means.
Gillon, R
1986-01-25
The Roman Catholic doctrine of ordinary and extraordinary means in patient care decisions is the subject of this essay in Gillon's series on medical ethics. He briefly traces the Church history of this doctrine, which holds that saving life is not obligatory if doing so would be excessively burdensome or disproportionate in relation to the expected benefits. The burdens and benefits are to be weighed in the context of "circumstances of persons, places, times, and cultures," and factors such as the costs and risks of undergoing a proposed treatment may be considered. Gillon also notes the disagreement among Roman Catholic commentators over whether it is ever permissible to discontinue feeding as a burdensome, extraordinary treatment. He concludes that, despite different weightings of harms and benefits, Roman Catholic and non-Catholic thinkers are in accord over the appropriate moral approach to deciding when treatment is not obligatory.
Parametric decay of an extraordinary electromagnetic wave in relativistic plasma
DOE Office of Scientific and Technical Information (OSTI.GOV)
Dorofeenko, V. G.; Krasovitskiy, V. B., E-mail: krasovit@mail.ru; Turikov, V. A.
2015-03-15
Parametric instability of an extraordinary electromagnetic wave in plasma preheated to a relativistic temperature is considered. A set of self-similar nonlinear differential equations taking into account the electron “thermal” mass is derived and investigated. Small perturbations of the parameters of the heated plasma are analyzed in the linear approximation by using the dispersion relation determining the phase velocities of the fast and slow extraordinary waves. In contrast to cold plasma, the evanescence zone in the frequency range above the electron upper hybrid frequency vanishes and the asymptotes of both branches converge. Theoretical analysis of the set of nonlinear equations showsmore » that the growth rate of decay instability increases with increasing initial temperature of plasma electrons. This result is qualitatively confirmed by numerical simulations of plasma heating by a laser pulse injected from vacuum.« less
Socio-cultural Input Facilitates Children’s Developing Understanding of Extraordinary Minds
Lane, Jonathan D.; Wellman, Henry M.; Evans, E. Margaret
2012-01-01
Three- to 5-year-old (N=61) religiously-schooled preschoolers received theory-of-mind tasks about the mental states of ordinary humans and agents with exceptional perceptual or mental capacities. Consistent with an anthropomorphism hypothesis, children beginning to appreciate limitations of human minds (e.g., ignorance) attributed those limits to God. Only 5-year-olds differentiated between humans’ fallible minds and God’s less fallible mind. Unlike secularly-schooled children, religiously-schooled 4-year-olds did appreciate another agent’s less fallible mental abilities when instructed and reminded about those abilities. Among children who understood ordinary humans’ mental fallibilities, knowledge of God predicted attributions of correct epistemic states to extraordinary agents. Results suggest that, at a certain point in theory-of-mind development, socio-cultural input can facilitate an appreciation for extraordinary minds. PMID:22372590
Learning new color names produces rapid increase in gray matter in the intact adult human cortex
Kwok, Veronica; Niu, Zhendong; Kay, Paul; Zhou, Ke; Mo, Lei; Jin, Zhen; So, Kwok-Fai; Tan, Li Hai
2011-01-01
The human brain has been shown to exhibit changes in the volume and density of gray matter as a result of training over periods of several weeks or longer. We show that these changes can be induced much faster by using a training method that is claimed to simulate the rapid learning of word meanings by children. Using whole-brain magnetic resonance imaging (MRI) we show that learning newly defined and named subcategories of the universal categories green and blue in a period of 2 h increases the volume of gray matter in V2/3 of the left visual cortex, a region known to mediate color vision. This pattern of findings demonstrates that the anatomical structure of the adult human brain can change very quickly, specifically during the acquisition of new, named categories. Also, prior behavioral and neuroimaging research has shown that differences between languages in the boundaries of named color categories influence the categorical perception of color, as assessed by judgments of relative similarity, by response time in alternative forced-choice tasks, and by visual search. Moreover, further behavioral studies (visual search) and brain imaging studies have suggested strongly that the categorical effect of language on color processing is left-lateralized, i.e., mediated by activity in the left cerebral hemisphere in adults (hence “lateralized Whorfian” effects). The present results appear to provide a structural basis in the brain for the behavioral and neurophysiologically observed indices of these Whorfian effects on color processing. PMID:21464316
Transformation of a Plane Wavefront in Hemispherical Lenses Made of Leuco-Sapphire
NASA Astrophysics Data System (ADS)
Vetrov, V. N.; Ignatenkov, B. A.; Yakobson, V. E.
2018-01-01
An algorithm for wavefront calculation of ordinary and extraordinary waves after propagation through hemispherical components made of a uniaxial crystal is developed. The influence of frequency dispersion of n o and n e , as well as change in the direction of the optic axis of the crystal, on extraordinary wavefront in hemispheres made of from leuco-sapphire and a plastically deformed analog thereof is determined.
Diker, Sevda; Has, Arzu Ceylan; Kurne, Aslı; Göçmen, Rahşan; Oğuz, Kader Karlı; Karabudak, Rana
2016-11-01
Multiple sclerosis can impair cognition from the early stages and has been shown to be associated with gray matter damage in addition to white matter pathology. To investigate the profile of cognitive impairment in clinically isolated syndrome (CIS), and the contribution of cortical inflammation, cortical and deep gray matter atrophy, and white matter lesions to cognitive decline. Thirty patients with clinically isolated syndrome and twenty demographically- matched healthy controls underwent neuropsychologic assessment through the Rao Brief Repeatable Battery, and brain magnetic resonance imaging with double inversion recovery using a 3T scanner. Patients with clinically isolated syndrome performed significantly worse than healthy controls on tests that evaluated verbal memory, visuospatial learning and memory, and verbal fluency. Significant deep gray matter atrophy was found in the patients but cortical volume was not lower than the controls. Visual memory tests correlated with the volume of the hippocampus, cerebral white matter and deep gray matter structures and with cerebellar cortical atrophy. Cortical or white matter lesion load did not affect cognitive test results. In our patients with CIS, it was shown that cognitive impairment was mainly related to cerebral white matter, cerebellar cortical and deep gray matter atrophy, but not with cortical inflammation, at least in the early stage of disease. Copyright © 2016 Elsevier B.V. All rights reserved.
Developing concepts of ordinary and extraordinary communication.
Lane, Jonathan D; Evans, E Margaret; Brink, Kimberly A; Wellman, Henry M
2016-01-01
We examine how understandings of ordinary and extraordinary communication develop. Three- to 10-year-old children and adults (N = 183) were given scenarios in which a protagonist wanted help from a human (their parent) or from God. Scenarios varied in whether protagonists expressed their desires aloud (by asking) or silently (by hoping), whether (for human scenarios) parents were nearby or far away, and whether (for God scenarios) protagonists expressed desires through ordinary means (asking or hoping) or more extraordinary means (praying). Following each scenario, participants were asked whether the recipient (either the parent or God) was aware of the protagonist's desire. Children as young as 3 to 4 years old understood that both loudness and distance limit the effectiveness of human communication, reporting that humans would most likely be aware of desires when they were expressed both aloud and nearby. As well, by this age children reported that God would more often be aware of desires than would humans, but children of all ages often reported that God (like humans) would be more aware of desires expressed aloud (rather than silently). These concepts of ordinary and extraordinary communication continued to be refined through middle childhood. Children's performance on standard theory-of-mind tasks and participants' religious background predicted whether they attributed awareness to God. (PsycINFO Database Record (c) 2015 APA, all rights reserved).
NASA Astrophysics Data System (ADS)
Tran, Lauren Christine
The Extraordinary Electroconductance (EEC) sensor has been previously demonstrated to have an electric field sensitivity of 3.05V/cm in a mesoscopic-scale structure fabricated at the center of a parallel plate capacitor. In this thesis, we demonstrate the first successful application of EEC sensors as electrochemical detectors of protein binding and biological molecule concentration. Using the avidin derivative, captavidin, in complex with the vitamin biotin, the change in four-point measured resistance with fluid protein concentration of bare EEC sensors was shown to increase by a factor of four in the presence of biomolecular binding as compared to baseline. Calculations for approximate field strengths introduced by a bound captavidin molecule are also presented. The development of Inverse-Extraordinary Optoconductance (I-EOC), an effect which occurs in nanoscale sensors, is also discussed. In the I-EOC effect, electron transport transitions from ballistic to diffusive with increasing light intensity. In these novel, room temperature optical detectors, the resistance is low at low light intensity and resistance increases by 9462% in a 250nm device mesa upon full illumination with a 5 mW HeNe laser. This is the inverse of bulk and mesoscopic device behavior, in which resistance decreases with increasing photon density.
NASA Astrophysics Data System (ADS)
Borisova, T. D.; Blagoveshchenskaya, N. F.; S. Kalishin, A.; Oksavik, K.; Baddelley, L.; K. Yeoman, T.
2012-06-01
We present the results of modifying the F2 layer of the polar ionosphere experimentally with highpower HF extraordinary-mode waves. The experiments were performed in October 2010 using the short-wave SPEAR heating facility (Longyearbyen, Spitsbergen). To diagnose the effects of high-power HF waves by the aspect-scattering method in a network of diagnostic paths, we used the short-wave Doppler radar CUTLASS (Hankasalmi, Finland) and the incoherent scatter radar ESR (Longyearbyen, Spitsbergen). Excitation of small-scale artificial ionospheric irregularities was revealed, which were responsible for the aspect and backward scattering of the diagnostic signals. The measurements performed by the ESR incoherent scatter radar simultaneously with the heating demonstrated changes in the parameters of the ionospheric plasma, specifically, an increase in the electron density by 10-25 % and an increase in the electron temperature by 10-30 % at the altitudes of the F2 layer, as well as formation of sporadic ionization at altitudes of 140-180 km (below the F2 layer maximum). To explain the effects of ionosphere heating with HF extraordinary-mode waves, we propose a hypothesis of transformation of extraordinary electromagnetic waves to ordinary in the anisotropic, smoothly nonuniform ionosphere.
Evidence of Pulsars Metamorphism and Their Connection to Stellar Black Holes
NASA Astrophysics Data System (ADS)
Hujeirat, A. A.
2018-03-01
It is agreed that the progenitors of neutron stars (-NSs) and black holes (-BHs) should be massive stars with M > 9 M_{Sun}. Yet none of these objects have ever been found with [2 M_{Sun}< M < 5 M_{Sun}]. Moreover, numerical modelings show that NSs of reasonable masses can be obtained only if the corresponding central density is beyond the nuclear one: an unverifiable density-regime with unknown physics. Here I intend to clarify the reasons underlying the existence of this mass-gap and propose a new class of invisible ultra-compact objects: the end-stage in the cosmological evolution of pulsars and neutron stars in an ever expanding universe. The present study relies on theoretical and experimental considerations as well as on solution of the non-linear TOV equation modified to include a universal scalar field -φ at the background of supranuclear densities. The computer-code is based on finite volume method using both the first-order Euler and fourth-order Rugge-Kutta integration methods. The inclusion of φ at zero-temperature is motivated by recent observations of the short-living pentaquarks at the LHC. Based on these studies, I argue that pulsars must be born with embryonic super-baryons (SBs) that form through merger of individual neutrons at their centers. The cores of SBs are made of purely incompressible superconducting gluon-quark superfluids (henceforth SuSu-fluids). Such quantum fluids have a uniform supranuclear density and governed by the critical EOSs P = E for baryonic matter and for φ-induced dark energy P_{φ}= -E_{φ}. The incompressibility here ensures that particles communicate at the shortest possible time scale, superfluidity and superconductivity enforce SBs to spin-down promptly as dictated by the Onsager-Feynman equation and to expel vortices and magnetic flux tubes, whereas their lowest energy state grants SBs lifetimes that are comparable to those of protons. These extra-ordinary long lifetimes suggest that conglomeration of SuSu-objects would evolve over several big bang events to possibly form dark matter halos that embed the galaxies in the observable universe. Pulsars and young neutron stars should metamorphose into SuSu-objects: a procedure which is predicted to last for one Gyr or even shorter, depending on their initial compactness. Once the process is completed, then they become extraordinary compact and turn invisible. It turns out that recent observations of particle collisions at the LHC and RHIC, observations of glitching pulsars and primordial galaxies remarkably support the present scenario.
Visualizing and improving the robustness of phase retrieval algorithms
Tripathi, Ashish; Leyffer, Sven; Munson, Todd; ...
2015-06-01
Coherent x-ray diffractive imaging is a novel imaging technique that utilizes phase retrieval and nonlinear optimization methods to image matter at nanometer scales. We explore how the convergence properties of a popular phase retrieval algorithm, Fienup's HIO, behave by introducing a reduced dimensionality problem allowing us to visualize and quantify convergence to local minima and the globally optimal solution. We then introduce generalizations of HIO that improve upon the original algorithm's ability to converge to the globally optimal solution.
Visualizing and improving the robustness of phase retrieval algorithms
DOE Office of Scientific and Technical Information (OSTI.GOV)
Tripathi, Ashish; Leyffer, Sven; Munson, Todd
Coherent x-ray diffractive imaging is a novel imaging technique that utilizes phase retrieval and nonlinear optimization methods to image matter at nanometer scales. We explore how the convergence properties of a popular phase retrieval algorithm, Fienup's HIO, behave by introducing a reduced dimensionality problem allowing us to visualize and quantify convergence to local minima and the globally optimal solution. We then introduce generalizations of HIO that improve upon the original algorithm's ability to converge to the globally optimal solution.
Disentangling How the Brain is “Wired” in Cortical/Cerebral Visual Impairment (CVI)
Merabet, Lotfi B.; Mayer, D. Luisa; Bauer, Corinna M.; Wright, Darick; Kran, Barry S.
2017-01-01
Cortical/cerebral visual impairment (CVI) results from perinatal injury to visual processing structures and pathways of the brain and is the most common cause of severe visual impairment/blindness in children in developed countries. Children with CVI display a wide range of visual deficits including decreased visual acuity, impaired visual field function, as well as impairments in higher order visual processing and attention. Together, these visual impairments can dramatically impact upon a child’s development and well-being. Given the complex neurological underpinnings of this condition, CVI is often undiagnosed by eye care practitioners. Furthermore, the neurophysiological basis of CVI in relation to observed visual processing deficits remains poorly understood. Here, we present some of the challenges associated with the clinical assessment and management of individuals with CVI. We discuss how advances in brain imaging are likely to help uncover the underlying neurophysiology of this condition. In particular, we demonstrate how structural and functional neuroimaging approaches can help gain insight into abnormalities of white matter connectivity and cortical activation patterns respectively. Establishing a connection between how changes within the brain relate to visual impairments in CVI will be important for developing effective rehabilitative and education strategies for individuals living with this condition. PMID:28941531
Disentangling How the Brain is "Wired" in Cortical (Cerebral) Visual Impairment.
Merabet, Lotfi B; Mayer, D Luisa; Bauer, Corinna M; Wright, Darick; Kran, Barry S
2017-05-01
Cortical (cerebral) visual impairment (CVI) results from perinatal injury to visual processing structures and pathways of the brain and is the most common cause of severe visual impairment or blindness in children in developed countries. Children with CVI display a wide range of visual deficits including decreased visual acuity, impaired visual field function, as well as impairments in higher-order visual processing and attention. Together, these visual impairments can dramatically influence a child's development and well-being. Given the complex neurologic underpinnings of this condition, CVI is often undiagnosed by eye care practitioners. Furthermore, the neurophysiological basis of CVI in relation to observed visual processing deficits remains poorly understood. Here, we present some of the challenges associated with the clinical assessment and management of individuals with CVI. We discuss how advances in brain imaging are likely to help uncover the underlying neurophysiology of this condition. In particular, we demonstrate how structural and functional neuroimaging approaches can help gain insight into abnormalities of white matter connectivity and cortical activation patterns, respectively. Establishing a connection between how changes within the brain relate to visual impairments in CVI will be important for developing effective rehabilitative and education strategies for individuals living with this condition. Copyright © 2017 Elsevier Inc. All rights reserved.
Demonstrations in Solute Transport Using Dyes: Part I. Procedures and Results.
ERIC Educational Resources Information Center
Butters, Greg; Bandaranayake, Wije
1993-01-01
Presents the general theory to explain chemical movement in soil. Describes classroom demonstrations with visually stimulating results that show the effects of soil structure, soil texture, soil pH, and soluble organic matter on that movement. (MDH)
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ding, Shulin; Wang, Guo Ping, E-mail: gpwang@szu.edu.cn; College of Electronic Science and Technology, Shenzhen University, Shenzhen 518060
In this paper, we present a kind of periodical ternary parity-time (PT) -symmetric multilayers to realize nearly 100% reflectance and transmittance simultaneously when light is incident from a certain direction. This extraordinary reflection and transmission is original from unidirectional Bragg reflection of PT-symmetric systems as the symmetry spontaneous breaking happens at PT thresholds. The extra energy involved in reflection and transmission lights is obtained from pumping light to the gain regions of the structure. Moreover, we find that our PT-symmetric structure shows direction dependent wavelength selectivity. When the illumination light is incident from two opposite directions into the multilayer structure,more » such extraordinary reflection and transmission appear at visible and near-infrared wavelengths, respectively. Such distinguishing properties may provide these structures with attractive applications as beam splitters, laser mirrors, narrow band filters, and multiband PT-symmetric optical devices.« less
NASA Astrophysics Data System (ADS)
Venkatesh, A.; Piragash Kumar, R. M.; Moorthy, V. H. S.
2018-05-01
We report the first observation of extraordinary transmission of deep-UV light (λ = 289nm) through 20nm aluminum film coated two-dimensional photonic crystals. The two-dimensional photonic crystals are made of self-assembled hexagonally arranged monolayer of 200 nm polystyrene spheres fabricated using drop casting method. The high quality photonic crystal exhibits a well-defined photonic band gap of 4.59 eV (λ = 270nm) and the aluminum coated two-dimensional photonic crystal displays extraordinary transmission in the deep-UV region at λ = 289 nm. The fabricated aluminum nanostructure produces a sensitivity of 42nm/RIU and 57nm/RIU when the refractive index of the surrounding medium is changed from 1 (= air) to 1.36 (= ethanol) and 1.49 (=toluene), respectively. Therefore, the aluminum film coated two-dimensional photonic crystals could be utilized to fabricate cost-effective and ultrasensitive chemical sensors.
NASA Astrophysics Data System (ADS)
Zhang, Jian; Irannejad, Mehrdad; Yavuz, Mustafa; Cui, Bo
2015-05-01
Nanofabrication technology plays an important role in the performance of surface plasmonic devices such as extraordinary optical transmission (EOT) sensor. In this work, a double liftoff process was developed to fabricate a series of nanohole arrays of a hole diameter between 150 and 235 nm and a period of 500 nm in a 100-nm-thick gold film on a silica substrate. To improve the surface quality of the gold film, thermal annealing was conducted, by which an ultra-smooth gold film with root-mean-square (RMS) roughness of sub-1 nm was achieved, accompanied with a hole diameter shrinkage. The surface sensitivity of the nanohole arrays was measured using a monolayer of 16-mercaptohexadecanoic acid (16-MHA) molecule, and the surface sensitivity was increased by 2.5 to 3 times upon annealing the extraordinary optical transmission (EOT) sensor.
NASA Astrophysics Data System (ADS)
Caglayan, Günhan
2015-08-01
Despite few limitations, GeoGebra as a dynamic geometry software stood as a powerful instrument in helping university math majors understand, explore, and gain experiences in visualizing the limits of functions and the ɛ - δ formalism. During the process of visualizing a theorem, the order mattered in the sequence of constituents. Students made use of such rich constituents as finger-hand gestures and cursor gestures in an attempt to keep a record of visual demonstration in progress, while being aware of the interrelationships among these constituents and the transformational aspect of the visually proving process. Covariational reasoning along with interval mapping structures proved to be the key constituents in the visualizing and sense-making of a limit theorem using the delta-epsilon formalism. Pedagogical approaches and teaching strategies based on experimental mathematics - mindtool - consituential visual proofs trio would permit students to study, construct, and meaningfully connect the new knowledge to the previously mastered concepts and skills in a manner that would make sense for them.
Cosmography and Data Visualization
NASA Astrophysics Data System (ADS)
Pomarède, Daniel; Courtois, Hélène M.; Hoffman, Yehuda; Tully, R. Brent
2017-05-01
Cosmography, the study and making of maps of the universe or cosmos, is a field where visual representation benefits from modern three-dimensional visualization techniques and media. At the extragalactic distance scales, visualization is contributing to our understanding of the complex structure of the local universe in terms of spatial distribution and flows of galaxies and dark matter. In this paper, we report advances in the field of extragalactic cosmography obtained using the SDvision visualization software in the context of the Cosmicflows Project. Here, multiple visualization techniques are applied to a variety of data products: catalogs of galaxy positions and galaxy peculiar velocities, reconstructed velocity field, density field, gravitational potential field, velocity shear tensor viewed in terms of its eigenvalues and eigenvectors, envelope surfaces enclosing basins of attraction. These visualizations, implemented as high-resolution images, videos, and interactive viewers, have contributed to a number of studies: the cosmography of the local part of the universe, the nature of the Great Attractor, the discovery of the boundaries of our home supercluster of galaxies Laniakea, the mapping of the cosmic web, and the study of attractors and repellers.
Steinhoff, Philip O M; Sombke, Andy; Liedtke, Jannis; Schneider, Jutta M; Harzsch, Steffen; Uhl, Gabriele
2017-03-01
Jumping spiders are known for their extraordinary cognitive abilities. The underlying nervous system structures, however, are largely unknown. Here, we explore and describe the anatomy of the brain in the jumping spider Marpissa muscosa (Clerck, 1757) by means of paraffin histology, X-ray microCT analysis and immunohistochemistry as well as three-dimensional reconstruction. In the prosoma, the CNS is a clearly demarcated mass that surrounds the esophagus. The anteriormost neuromere, the protocerebrum, comprises nine bilaterally paired neuropils, including the mushroom bodies and one unpaired midline neuropil, the arcuate body. Further ventrally, the synganglion comprises the cheliceral (deutocerebrum) and pedipalpal neuropils (tritocerebrum). Synapsin-immunoreactivity in all neuropils is generally strong, while allatostatin-immunoreactivity is mostly present in association with the arcuate body and the stomodeal bridge. The most prominent neuropils in the spider brain, the mushroom bodies and the arcuate body, were suggested to be higher integrating centers of the arthropod brain. The mushroom body in M. muscosa is connected to first and second order visual neuropils of the lateral eyes, and the arcuate body to the second order neuropils of the anterior median eyes (primary eyes) through a visual tract. The connection of both, visual neuropils and eyes and arcuate body, as well as their large size corroborates the hypothesis that these neuropils play an important role in cognition and locomotion control of jumping spiders. In addition, we show that the architecture of the brain of M. muscosa and some previously investigated salticids differs significantly from that of the wandering spider Cupiennius salei, especially with regard to structure and arrangement of visual neuropils and mushroom body. Thus, we need to explore the anatomical conformities and specificities of the brains of different spider taxa in order to understand evolutionary transformations of the arthropod brain. Copyright © 2016 Elsevier Ltd. All rights reserved.
Bublitz, Alexander; Weinhold, Severine R.; Strobel, Sophia; Dehnhardt, Guido; Hanke, Frederike D.
2017-01-01
Octopuses (Octopus vulgaris) are generally considered to possess extraordinary cognitive abilities including the ability to successfully perform in a serial reversal learning task. During reversal learning, an animal is presented with a discrimination problem and after reaching a learning criterion, the signs of the stimuli are reversed: the former positive becomes the negative stimulus and vice versa. If an animal improves its performance over reversals, it is ascribed advanced cognitive abilities. Reversal learning has been tested in octopus in a number of studies. However, the experimental procedures adopted in these studies involved pre-training on the new positive stimulus after a reversal, strong negative reinforcement or might have enabled secondary cueing by the experimenter. These procedures could have all affected the outcome of reversal learning. Thus, in this study, serial visual reversal learning was revisited in octopus. We trained four common octopuses (O. vulgaris) to discriminate between 2-dimensional stimuli presented on a monitor in a simultaneous visual discrimination task and reversed the signs of the stimuli each time the animals reached the learning criterion of ≥80% in two consecutive sessions. The animals were trained using operant conditioning techniques including a secondary reinforcer, a rod that was pushed up and down the feeding tube, which signaled the correctness of a response and preceded the subsequent primary reinforcement of food. The experimental protocol did not involve negative reinforcement. One animal completed four reversals and showed progressive improvement, i.e., it decreased its errors to criterion the more reversals it experienced. This animal developed a generalized response strategy. In contrast, another animal completed only one reversal, whereas two animals did not learn to reverse during the first reversal. In conclusion, some octopus individuals can learn to reverse in a visual task demonstrating behavioral flexibility even with a refined methodology. PMID:28223940
ApoE influences regional white-matter axonal density loss in Alzheimer's disease.
Slattery, Catherine F; Zhang, Jiaying; Paterson, Ross W; Foulkes, Alexander J M; Carton, Amelia; Macpherson, Kirsty; Mancini, Laura; Thomas, David L; Modat, Marc; Toussaint, Nicolas; Cash, David M; Thornton, John S; Henley, Susie M D; Crutch, Sebastian J; Alexander, Daniel C; Ourselin, Sebastien; Fox, Nick C; Zhang, Hui; Schott, Jonathan M
2017-09-01
Mechanisms underlying phenotypic heterogeneity in young onset Alzheimer disease (YOAD) are poorly understood. We used diffusion tensor imaging and neurite orientation dispersion and density imaging (NODDI) with tract-based spatial statistics to investigate apolipoprotein (APOE) ε4 modulation of white-matter damage in 37 patients with YOAD (22, 59% APOE ε4 positive) and 23 age-matched controls. Correlation between neurite density index (NDI) and neuropsychological performance was assessed in 4 white-matter regions of interest. White-matter disruption was more widespread in ε4+ individuals but more focal (posterior predominant) in the absence of an ε4 allele. NODDI metrics indicate fractional anisotropy changes are underpinned by combinations of axonal loss and morphological change. Regional NDI in parieto-occipital white matter correlated with visual object and spatial perception battery performance (right and left, both p = 0.02), and performance (nonverbal) intelligence (WASI matrices, right, p = 0.04). NODDI provides tissue-specific microstructural metrics of white-matter tract damage in YOAD, including NDI which correlates with focal cognitive deficits, and APOEε4 status is associated with different patterns of white-matter neurodegeneration. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.
NASA Astrophysics Data System (ADS)
Smith, Nathan
2008-03-01
SN 2006gy radiated far more energy in visual light than any other supernova so far, and potential explanations for its energy demands have implications for galactic chemical evolution and the deaths of the first stars. It remained bright for over 200 days, longer than any normal supernova, and it radiated more than 1051 ergs of luminous energy at visual wavelengths. I argue that this Type IIn supernova was probably the explosion of an extremely massive star like Eta Carinae that retained its hydrogen envelope when it exploded, having suffered relatively little mass loss during its lifetime. That this occurred at roughly Solar metallicity challenges current paradigms for mass loss in massive-star evolution. I explore a few potential explanations for SN2006gy's power source, involving either circumstellar interaction, or instead, the decay of 56Ni to 56Co to 56Fe. If SN 2006gy was powered by the conversion of shock energy into light, then the conditions must be truly extraordinary and traditional interaction models don't work. If SN 2006gy was powered by radioactive decay, then the uncomfortably huge 56Ni mass requires that the star exploded as a pair instability supernova. The mere possibility of this makes SN 2006gy interesting, especially at this meeting, because it is the first good candidate for a genuine pair instability supernova.
Sawosz, Ewa; Chwalibog, André; Szeliga, Jacek; Sawosz, Filip; Grodzik, Marta; Rupiewicz, Marlena; Niemiec, Tomasz; Kacprzyk, Katarzyna
2010-01-01
Purpose Rapid development of nanotechnology has recently brought significant attention to the extraordinary biological features of nanomaterials. The objective of the present investigation was to evaluate morphological characteristics of the assembles of gold and platinum nanoparticles (nano-Au and nano-Pt respectively), with Salmonella Enteritidis (Gram-negative) and Listeria monocytogenes (Gram-positive), to reveal possibilities of constructing bacteria-nanoparticle vehicles. Methods Hydrocolloids of nano-Au or nano-Pt were added to two bacteria suspensions in the following order: nano-Au + Salmonella Enteritidis; nano-Au + Listeria monocytogenes; nano-Pt + Salmonella Enteritidis; nano-Pt + Listeria monocytogenes. Samples were inspected by transmission electron microscope. Results Visualization of morphological interaction between nano-Au and Salmonella Enteritidis and Listeria monocytogenes, showed that nano-Au were aggregated within flagella or biofilm network and did not penetrate the bacterial cell. The analysis of morphological effects of interaction of nano-Pt with bacteria revealed that nano-Pt entered cells of Listeria monocytogenes and were removed from the cells. In the case of Salmonella Enteritidis, nano-Pt were seen inside bacteria cells, probably bound to DNA and partly left bacterial cells. After washing and centrifugation, some of the nano-Pt-DNA complexes were observed within Salmonella Enteritidis. Conclusion The results indicate that the bacteria could be used as a vehicle to deliver nano-Pt to specific points in the body. PMID:20856838
A Visual Galaxy Classification Interface and its Classroom Application
NASA Astrophysics Data System (ADS)
Kautsch, Stefan J.; Phung, Chau; VanHilst, Michael; Castro, Victor H
2014-06-01
Galaxy morphology is an important topic in modern astronomy to understand questions concerning the evolution and formation of galaxies and their dark matter content. In order to engage students in exploring galaxy morphology, we developed a web-based, graphical interface that allows students to visually classify galaxy images according to various morphological types. The website is designed with HTML5, JavaScript, PHP, and a MySQL database. The classification interface provides hands-on research experience and training for students and interested clients, and allows them to contribute to studies of galaxy morphology. We present the first results of a pilot study and compare the visually classified types using our interface with that from automated classification routines.
Neuroplasticity as a function of second language learning: anatomical changes in the human brain.
Li, Ping; Legault, Jennifer; Litcofsky, Kaitlyn A
2014-09-01
The brain has an extraordinary ability to functionally and physically change or reconfigure its structure in response to environmental stimulus, cognitive demand, or behavioral experience. This property, known as neuroplasticity, has been examined extensively in many domains. But how does neuroplasticity occur in the brain as a function of an individual's experience with a second language? It is not until recently that we have gained some understanding of this question by examining the anatomical changes as well as functional neural patterns that are induced by the learning and use of multiple languages. In this article we review emerging evidence regarding how structural neuroplasticity occurs in the brain as a result of one's bilingual experience. Our review aims at identifying the processes and mechanisms that drive experience-dependent anatomical changes, and integrating structural imaging evidence with current knowledge of functional neural plasticity of language and other cognitive skills. The evidence reviewed so far portrays a picture that is highly consistent with structural neuroplasticity observed for other domains: second language experience-induced brain changes, including increased gray matter (GM) density and white matter (WM) integrity, can be found in children, young adults, and the elderly; can occur rapidly with short-term language learning or training; and are sensitive to age, age of acquisition, proficiency or performance level, language-specific characteristics, and individual differences. We conclude with a theoretical perspective on neuroplasticity in language and bilingualism, and point to future directions for research. Copyright © 2014 Elsevier Ltd. All rights reserved.
Zhao, Congcong; Xie, Huijun; Zhang, Jian; Xu, Jingtao; Liang, Shuang
2013-03-01
The distribution and concentration of some organochlorine pesticides (OCPs) in the soil around a pesticide factory in Zibo, China, were examined, including dichlorodiphenyltrichloroethane (DDT) and its metabolites, isomers of hexachlorocyclohexane (HCH) and endosulfan (ENDO). The results showed that the OCPs concentrations were extraordinary high in this region. The concentrations of DDTs, HCHs, and ENDO were measured in the range of 0.775-226.711, 0.248-42.838, and 0.081-1.644 mg kg(-1), respectively. DDT and its isomers were identified to be the dominate contaminants in most of the sampling sites. In the vertical direction, the distribution pattern of the total OCPs was in order of DDTs, HCHs, and ENDO in the 0-20 cm, but in 20-40 and 40-60 cm the trends were unobvious. Although no recent input occurred in most areas, the residues of OCPs remained in deep soil due to their persistence. Unlike ENDO, DDTs and HCHs appeared to have the similar property in terms of not only the migration pattern in soil, but also the relationship to the same dominant impact factor (i.e. organic matter). DDTs and HCHs were affected positively by the organic matter, whereas ENDO was affected negatively. Due to the interrelationship among various impact factors, the spatial distribution of pesticides in the soil was considered to be a combined result. Copyright © 2012 Elsevier Ltd. All rights reserved.
MAIN software for density averaging, model building, structure refinement and validation
Turk, Dušan
2013-01-01
MAIN is software that has been designed to interactively perform the complex tasks of macromolecular crystal structure determination and validation. Using MAIN, it is possible to perform density modification, manual and semi-automated or automated model building and rebuilding, real- and reciprocal-space structure optimization and refinement, map calculations and various types of molecular structure validation. The prompt availability of various analytical tools and the immediate visualization of molecular and map objects allow a user to efficiently progress towards the completed refined structure. The extraordinary depth perception of molecular objects in three dimensions that is provided by MAIN is achieved by the clarity and contrast of colours and the smooth rotation of the displayed objects. MAIN allows simultaneous work on several molecular models and various crystal forms. The strength of MAIN lies in its manipulation of averaged density maps and molecular models when noncrystallographic symmetry (NCS) is present. Using MAIN, it is possible to optimize NCS parameters and envelopes and to refine the structure in single or multiple crystal forms. PMID:23897458
Einstein's First Steps Toward General Relativity: Gedanken Experiments and Axiomatics
NASA Astrophysics Data System (ADS)
Miller, A. I.
1999-03-01
Albert Einstein's 1907 Jahrbuch paper is an extraordinary document because it contains his first steps toward generalizing the 1905 relativity theory to include gravitation. Ignoring the apparent experimental disconfirmation of the 1905 relativity theory and his unsuccessful attempts to generalize the mass-energy equivalence, Einstein boldly raises the mass-energy equivalence to an axiom, invokes equality between gravitational and inertial masses, and then postulates the equivalence between a uniform gravitational field and an oppositely directed constant acceleration, the equivalence principle. How did this come about? What is at issue is scientific creativity. This necessitates broadening historical analysis to include aspects of cognitive science such as the role of visual imagery in Einstein's thinking, and the relation between conscious and unconscious modes of thought in problem solving. This method reveals the catalysts that sparked a Gedanken experiment that occurred to Einstein while working on the Jahrbuch paper. A mental model is presented to further explore Einstein's profound scientific discovery.
On supertaskers and the neural basis of efficient multitasking.
Medeiros-Ward, Nathan; Watson, Jason M; Strayer, David L
2015-06-01
The present study used brain imaging to determine the neural basis of individual differences in multitasking, the ability to successfully perform at least two attention-demanding tasks at once. Multitasking is mentally taxing and, therefore, should recruit the prefrontal cortex to maintain task goals when coordinating attentional control and managing the cognitive load. To investigate this possibility, we used functional neuroimaging to assess neural activity in both extraordinary multitaskers (Supertaskers) and control subjects who were matched on working memory capacity. Participants performed a challenging dual N-back task in which auditory and visual stimuli were presented simultaneously, requiring independent and continuous maintenance, updating, and verification of the contents of verbal and spatial working memory. With the task requirements and considerable cognitive load that accompanied increasing N-back, relative to the controls, the multitasking of Supertaskers was characterized by more efficient recruitment of anterior cingulate and posterior frontopolar prefrontal cortices. Results are interpreted using neuropsychological and evolutionary perspectives on individual differences in multitasking ability and the neural correlates of attentional control.
Visualizing decoupling in nanocrystalline alloys: A FORC-temperature analysis
NASA Astrophysics Data System (ADS)
Rivas, M.; Martínez-García, J. C.; Gorria, P.
2016-02-01
Devitrifying ferromagnetic amorphous precursors in the adequate conditions may give rise to disordered assemblies of densely packed nanocrystals with extraordinary magnetic softness well explained by the exchange coupling among multiple crystallites. Whether the magnetic exchange interaction is produced by direct contact or mediated by the intergranular amorphous matrix has a strong influence on the behaviour of the system above room temperature. Multi-phase amorphous-nanocrystalline systems dramatically harden when approaching the amorphous Curie temperature (TC) due to the hard grains decoupling. The study of the thermally induced decoupling of nanosized crystallites embedded in an amorphous matrix has been performed in this work by the first-order reversal curves (FORCs) analysis. We selected a Fe-rich amorphous alloy with TC = 330 K, in order to follow the evolution of the FORC diagrams obtained below and above such temperature in samples with different percentages of nanocrystalline phase. The existence of up to four regions exhibiting unlike magnetic behaviours is unambiguously determined from the temperature evolution of the FORC.
Retinal microvasculature and white matter microstructure: The Rotterdam Study.
Mutlu, Unal; Cremers, Lotte G M; de Groot, Marius; Hofman, Albert; Niessen, Wiro J; van der Lugt, Aad; Klaver, Caroline C W; Ikram, M Arfan; Vernooij, Meike W; Ikram, M Kamran
2016-09-06
To investigate whether retinal microvascular damage is related to normal-appearing white matter microstructure on diffusion tensor MRI. We included 2,436 participants (age ≥45 years) from the population-based Rotterdam Study (2005-2009) who had gradable retinal images and brain MRI scans. Retinal arteriolar and venular calibers were measured semiautomatically on fundus photographs. White matter microstructure was assessed using diffusion tensor MRI. We used linear regression models to investigate the associations of retinal vascular calibers with markers of normal-appearing white matter microstructure, adjusting for age, sex, the fellow vascular caliber, and additionally for structural MRI markers and cardiovascular risk factors. Narrower arterioles and wider venules were associated with poor white matter microstructure: adjusted difference in fractional anisotropy per SD decrease in arteriolar caliber -0.061 (95% confidence interval -0.106 to -0.016), increase in venular caliber -0.054 (-0.096 to -0.011), adjusted difference in mean diffusivity per SD decrease in arteriolar caliber 0.048 (0.007-0.088), and increase in venular caliber 0.047 (0.008-0.085). The associations for venules were more prominent in women. Retinal vascular calibers are related to normal-appearing white matter microstructure. This suggests that microvascular damage in the white matter is more widespread than visually detectable as white matter lesions. © 2016 American Academy of Neurology.
ERIC Educational Resources Information Center
School Science Review, 1983
1983-01-01
Provided are reviews of science films, slides, audio cassettes, and wall charts. Each review includes title, source, country of origin, description of subject matter presented, appraisal, and target audience. Among the topics considered are smell/taste, grasshopper behavior, photography, bat behavior/flight, pond life, exploring planets, locusts,…
Omizzolo, Cristina; Scratch, Shannon E; Stargatt, Robyn; Kidokoro, Hiroyuki; Thompson, Deanne K; Lee, Katherine J; Cheong, Jeanie; Neil, Jeffrey; Inder, Terrie E; Doyle, Lex W; Anderson, Peter J
2014-01-01
Using prospective longitudinal data from 198 very preterm and 70 full term children, this study characterised the memory and learning abilities of very preterm children at 7 years of age in both verbal and visual domains. The relationship between the extent of brain abnormalities on neonatal magnetic resonance imaging (MRI) and memory and learning outcomes at 7 years of age in very preterm children was also investigated. Neonatal MRI scans were qualitatively assessed for global, white-matter, cortical grey-matter, deep grey-matter, and cerebellar abnormalities. Very preterm children performed less well on measures of immediate memory, working memory, long-term memory, and learning compared with term-born controls. Neonatal brain abnormalities, and in particular deep grey-matter abnormality, were associated with poorer memory and learning performance at 7 years in very preterm children. Findings support the importance of cerebral neonatal pathology for predicting later memory and learning function.
High-contrast terahertz modulator based on extraordinary transmission through a ring aperture.
Shu, Jie; Qiu, Ciyuan; Astley, Victoria; Nickel, Daniel; Mittleman, Daniel M; Xu, Qianfan
2011-12-19
We demonstrated extraordinary THz transmission through ring apertures on a metal film. Transmission of 60% was obtained with an aperture-to-area ratio of only 1.4%. We show that the high transmission can be suppressed by over 18 dB with a thin layer of free carriers in the silicon substrate underneath the metal film. This result suggests that CMOS-compatible terahertz modulators can be built by controlling the carrier density near the aperture.
Extraordinary Transmission in the UV Range from Sub-wavelength Slits on Semiconductors
2010-03-01
M. Scalora, G. D’Aguanno, N. Mattiucci, M. J. Bloemer, J. W. Haus and A. M. Zheltikov, "Negative refraction of ultrashort electromagnetic pulses...a GaAs Substrate We consider a single layer of a GaAs having the linear dispersion profile taken from Palik’s handbook of optical constants [11...wavelength to investigate the relationship between the extraordinary transmission regime and the dispersion peculiarities of GaAs. As Fig.6 shows, the
Mapping Topographic Structure in White Matter Pathways with Level Set Trees
Kent, Brian P.; Rinaldo, Alessandro; Yeh, Fang-Cheng; Verstynen, Timothy
2014-01-01
Fiber tractography on diffusion imaging data offers rich potential for describing white matter pathways in the human brain, but characterizing the spatial organization in these large and complex data sets remains a challenge. We show that level set trees–which provide a concise representation of the hierarchical mode structure of probability density functions–offer a statistically-principled framework for visualizing and analyzing topography in fiber streamlines. Using diffusion spectrum imaging data collected on neurologically healthy controls (N = 30), we mapped white matter pathways from the cortex into the striatum using a deterministic tractography algorithm that estimates fiber bundles as dimensionless streamlines. Level set trees were used for interactive exploration of patterns in the endpoint distributions of the mapped fiber pathways and an efficient segmentation of the pathways that had empirical accuracy comparable to standard nonparametric clustering techniques. We show that level set trees can also be generalized to model pseudo-density functions in order to analyze a broader array of data types, including entire fiber streamlines. Finally, resampling methods show the reliability of the level set tree as a descriptive measure of topographic structure, illustrating its potential as a statistical descriptor in brain imaging analysis. These results highlight the broad applicability of level set trees for visualizing and analyzing high-dimensional data like fiber tractography output. PMID:24714673
Experimental realization of extraordinary acoustic transmission using Helmholtz resonators
DOE Office of Scientific and Technical Information (OSTI.GOV)
Crow, Brian C.; Cullen, Jordan M.; McKenzie, William W.
2015-02-15
The phenomenon of extraordinary acoustic transmission through a solid barrier with an embedded Helmholtz resonator (HR) is demonstrated. The Helmholtz resonator consists of an embedded cavity and two necks that protrude, one on each side of the barrier. Extraordinary transmission occurs for a narrow spectral range encompassing the resonant frequency of the Helmholtz resonator. We show that an amplitude transmission of 97.5% is achieved through a resonator whose neck creates an open area of 6.25% of the total barrier area. In addition to the enhanced transmission, we show that there is a smooth, continuous phase transition in the transmitted soundmore » as a function of frequency. The frequency dependent phase transition is used to experimentally realize slow wave propagation for a narrow-band Gaussian wave packet centered at the maximum transmission frequency. The use of parallel pairs of Helmholtz resonators tuned to different resonant frequencies is experimentally explored as a means of increasing the transmission bandwidth. These experiments show that because of the phase transition, there is always a frequency between the two Helmholtz resonant frequencies at which destructive interference occurs whether the resonances are close or far apart. Finally, we explain how the phase transition associated with Helmholtz-resonator-mediated extraordinary acoustic transmission can be exploited to produce diffractive acoustic components including sub-wavelength thickness acoustic lenses.« less
Edwards statistical mechanics for jammed granular matter
NASA Astrophysics Data System (ADS)
Baule, Adrian; Morone, Flaviano; Herrmann, Hans J.; Makse, Hernán A.
2018-01-01
In 1989, Sir Sam Edwards made the visionary proposition to treat jammed granular materials using a volume ensemble of equiprobable jammed states in analogy to thermal equilibrium statistical mechanics, despite their inherent athermal features. Since then, the statistical mechanics approach for jammed matter—one of the very few generalizations of Gibbs-Boltzmann statistical mechanics to out-of-equilibrium matter—has garnered an extraordinary amount of attention by both theorists and experimentalists. Its importance stems from the fact that jammed states of matter are ubiquitous in nature appearing in a broad range of granular and soft materials such as colloids, emulsions, glasses, and biomatter. Indeed, despite being one of the simplest states of matter—primarily governed by the steric interactions between the constitutive particles—a theoretical understanding based on first principles has proved exceedingly challenging. Here a systematic approach to jammed matter based on the Edwards statistical mechanical ensemble is reviewed. The construction of microcanonical and canonical ensembles based on the volume function, which replaces the Hamiltonian in jammed systems, is discussed. The importance of approximation schemes at various levels is emphasized leading to quantitative predictions for ensemble averaged quantities such as packing fractions and contact force distributions. An overview of the phenomenology of jammed states and experiments, simulations, and theoretical models scrutinizing the strong assumptions underlying Edwards approach is given including recent results suggesting the validity of Edwards ergodic hypothesis for jammed states. A theoretical framework for packings whose constitutive particles range from spherical to nonspherical shapes such as dimers, polymers, ellipsoids, spherocylinders or tetrahedra, hard and soft, frictional, frictionless and adhesive, monodisperse, and polydisperse particles in any dimensions is discussed providing insight into a unifying phase diagram for all jammed matter. Furthermore, the connection between the Edwards ensemble of metastable jammed states and metastability in spin glasses is established. This highlights the fact that the packing problem can be understood as a constraint satisfaction problem for excluded volume and force and torque balance leading to a unifying framework between the Edwards ensemble of equiprobable jammed states and out-of-equilibrium spin glasses.
Longitudinal structure of stationary planetary waves in the middle atmosphere - extraordinary years
NASA Astrophysics Data System (ADS)
Lastovicka, Jan; Krizan, Peter; Kozubek, Michal
2018-01-01
One important but little studied factor in the middle atmosphere meridional circulation is its longitudinal structure. Kozubek et al. (2015) disclosed the existence of the two-cell longitudinal structure in meridional wind at 10 hPa at higher latitudes in January. This two-cell structure is a consequence of the stratospheric stationary wave SPW1 in geopotential heights. Therefore here the longitudinal structure in geopotential heights and meridional wind is analysed based on MERRA data over 1979-2013 and limited NOGAPS-ALPHA data in order to find its persistence and altitudinal dependence with focus on extraordinary years. The SPW1 in geopotential heights and related two-cell structure in meridional wind covers the middle stratosphere (lower boundary ˜ 50 hPa), upper stratosphere and most of the mesosphere (almost up to about 0.01 hPa). The two-cell longitudinal structure in meridional wind is a relatively persistent feature; only 9 out of 35 winters (Januaries) display more complex structure. Morphologically the deviation of these extraordinary Januaries consists in upward propagation of the second (Euro-Atlantic) peak (i.e. SPW2 structure) to higher altitudes than usually, mostly up to the mesosphere. All these Januaries occurred under the positive phase of PNA (Pacific North American) index but there are also other Januaries under its positive phase, which behave in an ordinary way. The decisive role in the existence of extraordinary years (Januaries) appears to be played by the SPW filtering by the zonal wind pattern. In all ordinary years the mean zonal wind pattern in January allows the upward propagation of SPW1 (Aleutian peak in geopotential heights) up to the mesosphere but it does not allow the upward propagation of the Euro-Atlantic SPW2 peak to and above the 10 hPa level. On the other hand, the mean zonal wind filtering pattern in extraordinary Januaries is consistent with the observed pattern of geopotential heights at higher altitudes.
ERIC Educational Resources Information Center
Waller, Edmund
1991-01-01
Basic training in the earth sciences, social sciences, and visual arts is discussed as essential for the education and training of government advisers on physical planning matters. Urban planning examples are presented that highlight the ecological factors, social influences, and aesthetic values which need to be considered when dealing with…
A unified science of concussion
Maruta, Jun; Lee, Stephanie W; Jacobs, Emily F; Ghajar, Jamshid
2010-01-01
The etiology, imaging, and behavioral assessment of mild traumatic brain injury (mTBI) are daunting fields, given the lack of a cohesive neurobiological explanation for the observed cognitive deficits seen following mTBI. Although subjective patient self-report is the leading method of diagnosing mTBI, current scientific evidence suggests that quantitative measures of predictive timing, such as visual tracking, could be a useful adjunct to guide the assessment of attention and to screen for advanced brain imaging. Magnetic resonance diffusion tensor imaging (DTI) has demonstrated that mTBI is associated with widespread microstructural changes that include those in the frontal white matter tracts. Deficits observed during predictive visual tracking correlate with DTI findings that show lesions localized in neural pathways subserving the cognitive functions often disrupted in mTBI. Unifying the anatomical and behavioral approaches, the emerging evidence supports an explanation for mTBI that the observed cognitive impairments are a result of predictive timing deficits caused by shearing injuries in the frontal white matter tracts. PMID:20955326
Bota, Mihail; Talpalaru, Ştefan; Hintiryan, Houri; Dong, Hong-Wei; Swanson, Larry W.
2014-01-01
We present in this paper a novel neuroinformatic platform, the BAMS2 Workspace (http://brancusi1.usc.edu), designed for storing and processing information about gray matter region axonal connections. This de novo constructed module allows registered users to directly collate their data by using a simple and versatile visual interface. It also allows construction and analysis of sets of connections associated with gray matter region nomenclatures from any designated species. The Workspace includes a set of tools allowing the display of data in matrix and networks formats, and the uploading of processed information in visual, PDF, CSV, and Excel formats. Finally, the Workspace can be accessed anonymously by third party systems to create individualized connectivity networks. All features of the BAMS2 Workspace are described in detail, and are demonstrated with connectivity reports collated in BAMS and associated with the rat sensory-motor cortex, medial frontal cortex, and amygdalar regions. PMID:24668342
1988-04-01
the common law of extraordinary writs has ancient origins, they continue to be used in both the 9 military and civilian sectors. The most frequently...months and reduction to the pay grade E-1.178 Since the most the convening authority could legally approve under the pretrial agreement was a suspended bad...no*constitutional right to be free pending appeal, 268 there is a traditional right to bail pending appeal which Congress and most states have codified
DAISY Nurses-Recognizing Clinical Expertise Through Certification.
Sweeney, Cynthia Divens
2018-04-01
The DAISY Foundation is dedicated to recognizing nurses who provide compassionate, skilled, and extraordinary nursing care. Nominations for The DAISY Award are typically submitted in the form of a story. Stories are an opportunity to share with others what compassionate and extraordinary nursing care looks like and to recognize the individual nurses who provide that care. Clinical competence delivered with compassion is a hallmark of DAISY Award recipients. Professional certification provides an additional form of recognition of a nurse's clinical competence.
Method matters: Systematic effects of testing procedure on visual working memory sensitivity
Makovski, Tal; Watson, Leah M.; Koutstaal, Wilma; Jiang, Yuhong V.
2010-01-01
Visual working memory (WM) is traditionally considered a robust form of visual representation that survives changes in object motion, observer's position, and other visual transients. This study presents data that are inconsistent with the traditional view. We show that memory sensitivity is dramatically influenced by small variations in the testing procedure, supporting the idea that representations in visual WM are susceptible to interference from testing. In this study, participants were shown an array of colors to remember. After a short retention interval, memory for one of the items was tested with either a same-different task or a 2-alternative-forced-choice (2AFC) task. Memory sensitivity was much lower in the 2AFC task than in the same-different task. This difference was found regardless of encoding similarity or whether visual WM required a fine memory resolution or a coarse resolution. The 2AFC disadvantage was reduced when participants were informed shortly before testing which item would be probed. The 2AFC disadvantage diminished in perceptual tasks and was not found in tasks probing visual long-term memory. These results support memory models that acknowledge the labile nature of visual WM, and have implications for the format of visual WM and its assessment. PMID:20854011
Structural reorganization of the early visual cortex following Braille training in sighted adults.
Bola, Łukasz; Siuda-Krzywicka, Katarzyna; Paplińska, Małgorzata; Sumera, Ewa; Zimmermann, Maria; Jednoróg, Katarzyna; Marchewka, Artur; Szwed, Marcin
2017-12-12
Training can induce cross-modal plasticity in the human cortex. A well-known example of this phenomenon is the recruitment of visual areas for tactile and auditory processing. It remains unclear to what extent such plasticity is associated with changes in anatomy. Here we enrolled 29 sighted adults into a nine-month tactile Braille-reading training, and used voxel-based morphometry and diffusion tensor imaging to describe the resulting anatomical changes. In addition, we collected resting-state fMRI data to relate these changes to functional connectivity between visual and somatosensory-motor cortices. Following Braille-training, we observed substantial grey and white matter reorganization in the anterior part of early visual cortex (peripheral visual field). Moreover, relative to its posterior, foveal part, the peripheral representation of early visual cortex had stronger functional connections to somatosensory and motor cortices even before the onset of training. Previous studies show that the early visual cortex can be functionally recruited for tactile discrimination, including recognition of Braille characters. Our results demonstrate that reorganization in this region induced by tactile training can also be anatomical. This change most likely reflects a strengthening of existing connectivity between the peripheral visual cortex and somatosensory cortices, which suggests a putative mechanism for cross-modal recruitment of visual areas.
Pagnozzi, Alex M; Dowson, Nicholas; Doecke, James; Fiori, Simona; Bradley, Andrew P; Boyd, Roslyn N; Rose, Stephen
2016-01-01
White and grey matter lesions are the most prevalent type of injury observable in the Magnetic Resonance Images (MRIs) of children with cerebral palsy (CP). Previous studies investigating the impact of lesions in children with CP have been qualitative, limited by the lack of automated segmentation approaches in this setting. As a result, the quantitative relationship between lesion burden has yet to be established. In this study, we perform automatic lesion segmentation on a large cohort of data (107 children with unilateral CP and 18 healthy children) with a new, validated method for segmenting both white matter (WM) and grey matter (GM) lesions. The method has better accuracy (94%) than the best current methods (73%), and only requires standard structural MRI sequences. Anatomical lesion burdens most predictive of clinical scores of motor, cognitive, visual and communicative function were identified using the Least Absolute Shrinkage and Selection operator (LASSO). The improved segmentations enabled identification of significant correlations between regional lesion burden and clinical performance, which conform to known structure-function relationships. Model performance was validated in an independent test set, with significant correlations observed for both WM and GM regional lesion burden with motor function (p < 0.008), and between WM and GM lesions alone with cognitive and visual function respectively (p < 0.008). The significant correlation of GM lesions with functional outcome highlights the serious implications GM lesions, in addition to WM lesions, have for prognosis, and the utility of structural MRI alone for quantifying lesion burden and planning therapy interventions.
Lenz, Robin; Enders, Kristina; Stedmon, Colin A; Mackenzie, David M A; Nielsen, Torkel Gissel
2015-11-15
Identification and characterisation of microplastic (MP) is a necessary step to evaluate their concentrations, chemical composition and interactions with biota. MP ≥10μm diameter filtered from below the sea surface in the European and subtropical North Atlantic were simultaneously identified by visual microscopy and Raman micro-spectroscopy. Visually identified particles below 100μm had a significantly lower percentage confirmed by Raman than larger ones indicating that visual identification alone is inappropriate for studies on small microplastics. Sixty-eight percent of visually counted MP (n=1279) were spectroscopically confirmed being plastic. The percentage varied with type, colour and size of the MP. Fibres had a higher success rate (75%) than particles (64%). We tested Raman micro-spectroscopy applicability for MP identification with respect to varying chemical composition (additives), degradation state and organic matter coating. Partially UV-degraded post-consumer plastics provided identifiable Raman spectra for polymers most common among marine MP, i.e. polyethylene and polypropylene. Copyright © 2015 Elsevier Ltd. All rights reserved.
Comparing two types of engineering visualizations: task-related manipulations matter.
Cölln, Martin C; Kusch, Kerstin; Helmert, Jens R; Kohler, Petra; Velichkovsky, Boris M; Pannasch, Sebastian
2012-01-01
This study focuses on the comparison of traditional engineering drawings with a CAD (computer aided design) visualization in terms of user performance and eye movements in an applied context. Twenty-five students of mechanical engineering completed search tasks for measures in two distinct depictions of a car engine component (engineering drawing vs. CAD model). Besides spatial dimensionality, the display types most notably differed in terms of information layout, access and interaction options. The CAD visualization yielded better performance, if users directly manipulated the object, but was inferior, if employed in a conventional static manner, i.e. inspecting only predefined views. An additional eye movement analysis revealed longer fixation durations and a stronger increase of task-relevant fixations over time when interacting with the CAD visualization. This suggests a more focused extraction and filtering of information. We conclude that the three-dimensional CAD visualization can be advantageous if its ability to manipulate is used. Copyright © 2011 Elsevier Ltd and The Ergonomics Society. All rights reserved.
ICASE/LaRC Symposium on Visualizing Time-Varying Data
NASA Technical Reports Server (NTRS)
Banks, D. C. (Editor); Crockett, T. W. (Editor); Stacy, K. (Editor)
1996-01-01
Time-varying datasets present difficult problems for both analysis and visualization. For example, the data may be terabytes in size, distributed across mass storage systems at several sites, with time scales ranging from femtoseconds to eons. In response to these challenges, ICASE and NASA Langley Research Center, in cooperation with ACM SIGGRAPH, organized the first symposium on visualizing time-varying data. The purpose was to bring the producers of time-varying data together with visualization specialists to assess open issues in the field, present new solutions, and encourage collaborative problem-solving. These proceedings contain the peer-reviewed papers which were presented at the symposium. They cover a broad range of topics, from methods for modeling and compressing data to systems for visualizing CFD simulations and World Wide Web traffic. Because the subject matter is inherently dynamic, a paper proceedings cannot adequately convey all aspects of the work. The accompanying video proceedings provide additional context for several of the papers.
What you say matters: exploring visual-verbal interactions in visual working memory.
Mate, Judit; Allen, Richard J; Baqués, Josep
2012-01-01
The aim of this study was to explore whether the content of a simple concurrent verbal load task determines the extent of its interference on memory for coloured shapes. The task consisted of remembering four visual items while repeating aloud a pair of words that varied in terms of imageability and relatedness to the task set. At test, a cue appeared that was either the colour or the shape of one of the previously seen objects, with participants required to select the object's other feature from a visual array. During encoding and retention, there were four verbal load conditions: (a) a related, shape-colour pair (from outside the experimental set, i.e., "pink square"); (b) a pair of unrelated but visually imageable, concrete, words (i.e., "big elephant"); (c) a pair of unrelated and abstract words (i.e., "critical event"); and (d) no verbal load. Results showed differential effects of these verbal load conditions. In particular, imageable words (concrete and related conditions) interfered to a greater degree than abstract words. Possible implications for how visual working memory interacts with verbal memory and long-term memory are discussed.
Magnetic resonance in studies of glaucoma
Fiedorowicz, Michał; Dyda, Wojciech; Rejdak, Robert; Grieb, Paweł
2011-01-01
Summary Glaucoma is the second leading cause of blindness. It affects retinal ganglion cells and the optic nerve. However, there is emerging evidence that glaucoma also affects other components of the visual pathway and visual cortex. There is a need to employ new methods of in vivo brain evaluation to characterize these changes. Magnetic resonance (MR) techniques are well suited for this purpose. We review data on the MR evaluation of the visual pathway and the use of MR techniques in the study of glaucoma, both in humans and in animal models. These studies demonstrated decreases in optic nerve diameter, localized white matter loss and decrease in visual cortex density. Studies on rats employing manganese-enhanced MRI showed that axonal transport in the optic nerve is affected. Diffusion tensor MRI revealed signs of degeneration of the optic pathway. Functional MRI showed decreased response of the visual cortex after stimulation of the glaucomatous eye. Magnetic resonance spectroscopy demonstrated changes in metabolite levels in the visual cortex in a rat model of glaucoma, although not in glaucoma patients. Further applications of MR techniques in studies of glaucomatous brains are indicated. PMID:21959626
Flatland Photonics: Circumventing Diffraction with Planar Plasmonic Architectures
NASA Astrophysics Data System (ADS)
Dionne, Jennifer Anne
On subwavelength scales, photon-matter interactions are limited by diffraction. The diffraction limit restricts the size of optical devices and the resolution of conventional microscopes to wavelength-scale dimensions, severely hampering our ability to control and probe subwavelength-scale optical phenomena. Circumventing diffraction is now a principle focus of integrated nanophotonics. Surface plasmons provide a particularly promising approach to sub-diffraction-limited photonics. Surface plasmons are hybrid electron-photon modes confined to the interface between conductors and transparent materials. Combining the high localization of electronic waves with the propagation properties of optical waves, plasmons can achieve extremely small mode wavelengths and large local electromagnetic field intensities. Through their unique dispersion, surface plasmons provide access to an enormous phase space of refractive indices and propagation constants that can be readily tuned with material or geometry. In this thesis, we explore both the theory and applications of dispersion in planar plasmonic architectures. Particular attention is given to the modes of metallic core and plasmon slot waveguides, which can span positive, near-zero, and even negative indices. We demonstrate how such basic plasmonic geometries can be used to develop a suite of passive and active plasmonic components, including subwavelength waveguides, color filters, negative index metamaterials, and optical MOS field effect modulators. Positive index modes are probed by near- and far-field techniques, revealing plasmon wavelengths as small as one-tenth of the excitation wavelength. Negative index modes are characterized through direct visualization of negative refraction. By fabricating prisms comprised of gold, silicon nitride, and silver multilayers, we achieve the first experimental demonstration of a negative index material at visible frequencies, with potential applications for sub-diffraction-limited microscopy and electromagnetic cloaking. We exploit this tunability of complex plasmon mode indices to create a compact metal-oxide-Si (MOS) field effect plasmonic modulator (or plasMOStor). By transforming the MOS gate oxide into an optical channel, amplitude modulation depths of 11.2 dB are achieved in device volumes as small as one one-fifth of a cubic wavelength. Our results indicate the accessibility of tunable refractive indices over a wide frequency band, facilitating design of a new materials class with extraordinary optical properties and applications.
76 FR 3880 - Procurement List; Additions and Deletions
Federal Register 2010, 2011, 2012, 2013, 2014
2011-01-21
... Procurement List. After consideration of the relevant matter presented, the Committee has determined that the..., Black. NSN: 6230-01-513-3284--Flashlight, Aluminum, 4D, Black. NSN: 6230-01-513-3286--Flashlight, Aluminum, 5D, Black. NPA: Central Association for the Blind & Visually Impaired, Utica, NY. Contracting...
Teaching the Rules of Debit and Credit
ERIC Educational Resources Information Center
Potts, Andrew J.
1974-01-01
A fundamental method of explaining the basic accounting principles and concepts (debit, credit, basic accounting equation) which includes visual aids, reference to local businesses, and drill, does much toward increasing the student's skill and enhancing his understanding of the subject matter. (Sample transparencies are included.) (Author/AJ)
40 CFR 63.9631 - What are my monitoring requirements?
Code of Federal Regulations, 2010 CFR
2010-07-01
... maintain a bag leak detection system to monitor the relative change in particulate matter loadings... of ensuring the proper functioning of removal mechanisms. (3) Check the compressed air supply of... interior for air leaks. (8) Inspect fans for wear, material buildup, and corrosion through quarterly visual...
Airborne fine particulate matter across the United States is monitored by different networks, the three prevalent ones presently being the Clean Air Status and Trend Network (CASTNet), the Interagency Monitoring of PROtected Visual Environment Network (IMPROVE) and the Speciati...
Rothen, Nicolas; Meier, Beat
2010-04-01
In synaesthesia, the input of one sensory modality automatically triggers an additional experience, not normally triggered by the input of that modality. Therefore, compared to non-synaesthetes, additional experiences exist and these may be used as retrieval cues when memory is tested. Previous case studies have suggested that synaesthesia may yield even extraordinary memory abilities. However, group studies found either a task-specific memory advantage or no performance advantage at all. The aim of the present study was to test whether grapheme-colour synaesthesia gives rise to a general memory benefit using a standardised memory test (Wechsler Memory Scale). The synaesthetes showed a performance advantage in episodic memory tests, but not in short-term memory tests. However, performance was still within the ordinary range. The results support the hypothesis that synaesthesia provides for a richer world of experience and as a consequence additional retrieval cues may be available and beneficial but not to the point of extraordinary memory ability.
Medium-Range Forecast Skill for Extraordinary Arctic Cyclones in Summer of 2008-2016
NASA Astrophysics Data System (ADS)
Yamagami, Akio; Matsueda, Mio; Tanaka, Hiroshi L.
2018-05-01
Arctic cyclones (ACs) are a severe atmospheric phenomenon that affects the Arctic environment. This study assesses the forecast skill of five leading operational medium-range ensemble forecasts for 10 extraordinary ACs that occurred in summer during 2008-2016. Average existence probability of the predicted ACs was >0.9 at lead times of ≤3.5 days. Average central position error of the predicted ACs was less than half of the mean radius of the 10 ACs (469.1 km) at lead times of 2.5-4.5 days. Average central pressure error of the predicted ACs was 5.5-10.7 hPa at such lead times. Therefore, the operational ensemble prediction systems generally predict the position of ACs within 469.1 km 2.5-4.5 days before they mature. The forecast skill for the extraordinary ACs is lower than that for midlatitude cyclones in the Northern Hemisphere but similar to that in the Southern Hemisphere.
Kim, Seyoon; Jang, Min Seok; Brar, Victor W.; ...
2016-08-08
In this paper, subwavelength metallic slit arrays have been shown to exhibit extraordinary optical transmission, whereby tunneling surface plasmonic waves constructively interfere to create large forward light propagation. The intricate balancing needed for this interference to occur allows for resonant transmission to be highly sensitive to changes in the environment. Here we demonstrate that extraordinary optical transmission resonance can be coupled to electrostatically tunable graphene plasmonic ribbons to create electrostatic modulation of mid-infrared light. Absorption in graphene plasmonic ribbons situated inside metallic slits can efficiently block the coupling channel for resonant transmission, leading to a suppression of transmission. Full-wave simulationsmore » predict a transmission modulation of 95.7% via this mechanism. Experimental measurements reveal a modulation efficiency of 28.6% in transmission at 1,397 cm –1, corresponding to a 2.67-fold improvement over transmission without a metallic slit array. This work paves the way for enhancing light modulation in graphene plasmonics by employing noble metal plasmonic structures.« less
Brethel-Haurwitz, Kristin M.; Stoycos, Sarah A.; Cardinale, Elise M.; Huebner, Bryce; Marsh, Abigail A.
2016-01-01
In the Ultimatum Game (UG), incurring a cost to punish inequity is commonly termed altruistic punishment. This behaviour is thought to benefit others if the defector becomes more equitable in future interactions. However, clear connections between punishment in the UG and altruistic behaviours outside the laboratory are lacking. We tested the altruistic punishment hypothesis in a sample of extraordinarily altruistic adults, predicting that if punishing inequity is predictive of altruism more broadly, extraordinary altruists should punish more frequently. Results showed that punishment was not more prevalent in extraordinary altruists than controls. However, a self-reported altruism measure previously linked to peer evaluations but not behaviour, and on which extraordinary altruists and controls did not differ, did predict punishment. These findings support suggestions that altruistic punishment in the UG is better termed costly punishment and may be motivated by social, but not necessarily prosocial, concerns. Results also support prior suggestions that self-reported altruism may not reliably predict altruistic behaviour. PMID:26739364
An exploratory study into the effects of extraordinary nature on emotions, mood, and prosociality
Joye, Yannick; Bolderdijk, Jan Willem
2015-01-01
Environmental psychology research has demonstrated that exposure to mundane natural environments can be psychologically beneficial, and can, for instance, improve individuals' mood and concentration. However, little research has yet examined the psychological benefits of extraordinary, awe-evoking kinds of nature, such as spectacular mountain scenes or impressive waterfalls. In this study, we aimed to address the underrepresentation of such extraordinary nature in research on human—nature interactions. Specifically, we examined whether watching a picture slideshow of awesome as opposed to mundane nature differentially affected individuals' emotions, mood, social value orientation (SVO), and their willingness to donate something to others. Our analyses revealed that, compared to mundane nature and a neutral condition, watching awesome natural scenes and phenomena had some unique and pronounced emotional effects (e.g., feeling small and humble), triggered the most mood improvement, and led to a more prosocial SVO. We found that participants' willingness to donate did not differ significantly for any of the conditions. PMID:25674067
Brethel-Haurwitz, Kristin M; Stoycos, Sarah A; Cardinale, Elise M; Huebner, Bryce; Marsh, Abigail A
2016-01-07
In the Ultimatum Game (UG), incurring a cost to punish inequity is commonly termed altruistic punishment. This behaviour is thought to benefit others if the defector becomes more equitable in future interactions. However, clear connections between punishment in the UG and altruistic behaviours outside the laboratory are lacking. We tested the altruistic punishment hypothesis in a sample of extraordinarily altruistic adults, predicting that if punishing inequity is predictive of altruism more broadly, extraordinary altruists should punish more frequently. Results showed that punishment was not more prevalent in extraordinary altruists than controls. However, a self-reported altruism measure previously linked to peer evaluations but not behaviour, and on which extraordinary altruists and controls did not differ, did predict punishment. These findings support suggestions that altruistic punishment in the UG is better termed costly punishment and may be motivated by social, but not necessarily prosocial, concerns. Results also support prior suggestions that self-reported altruism may not reliably predict altruistic behaviour.
The artist emerges: visual art learning alters neural structure and function.
Schlegel, Alexander; Alexander, Prescott; Fogelson, Sergey V; Li, Xueting; Lu, Zhengang; Kohler, Peter J; Riley, Enrico; Tse, Peter U; Meng, Ming
2015-01-15
How does the brain mediate visual artistic creativity? Here we studied behavioral and neural changes in drawing and painting students compared to students who did not study art. We investigated three aspects of cognition vital to many visual artists: creative cognition, perception, and perception-to-action. We found that the art students became more creative via the reorganization of prefrontal white matter but did not find any significant changes in perceptual ability or related neural activity in the art students relative to the control group. Moreover, the art students improved in their ability to sketch human figures from observation, and multivariate patterns of cortical and cerebellar activity evoked by this drawing task became increasingly separable between art and non-art students. Our findings suggest that the emergence of visual artistic skills is supported by plasticity in neural pathways that enable creative cognition and mediate perceptuomotor integration. Copyright © 2014 Elsevier Inc. All rights reserved.
NASA Astrophysics Data System (ADS)
Wei, Yufen; Fang, Zhanqiang; Zheng, Liuchun; Tsang, Eric Pokeung
2017-03-01
Eichhornia crassipes (water hyacinth), a species of invasive weeds has caused serious ecological damage due to its extraordinary fertility and growth rate. However, it has not yet been exploited for use as a resource. This paper reported the synthesis and characterization of amorphous iron nanoparticles (Ec-Fe-NPs) from Fe(III) salts in aqueous extracts of Eichhornia crassipes. The nanoparticles were characterized by SEM, EDS, TEM, XPS, FTIR, DLS and the zeta potential methods. The characterization results confirmed the successful synthesis of amorphous iron nanoparticles with diameters of 20-80 nm. Moreover, the nanoparticles were mainly composed of zero valent iron nanoparticles which were coated with various organic matters in the extracts as a capping or stabilizing agents. Batch experiments showed that 89.9% of Cr(VI) was removed by the Ec-Fe-NPs much higher than by the extracts alone (20.4%) and Fe3O4 nanoparticles (47.3%). Based on the kinetics study and the XPS analysis, a removal mechanism dominated by adsorption and reduction with subsequently co-precipitation was proposed.
“Dark matter” worlds of unstable RNA and protein
Baboo, Sabyasachi; Cook, Peter R
2014-01-01
Astrophysicists use the term “dark matter” to describe the majority of the matter and/or energy in the universe that is hidden from view, and biologists now apply it to the new families of RNA they are uncovering. We review evidence for an analogous hidden world containing peptides. The critical experiments involved pulse-labeling human cells with tagged amino acids for periods as short as five seconds. Results are extraordinary in two respects: both nucleus and cytoplasm become labeled, and most signals disappear with a half-life of less than one minute. Just as the synthesis of each mature mRNA is regulated by the abortive production of hundreds of shorter transcripts that are quickly degraded, it seems that the synthesis of each full-length protein in the stable proteome is regulated by an apparently wasteful production and degradation of shorter peptides. Some of the nuclear synthesis is probably a byproduct of nuclear ribosomes proofreading newly-made RNA for inappropriately-placed termination codons (a process that triggers “nonsense-mediated decay”). We speculate that some “dark-matter” peptides will play other important roles in the cell. PMID:25482115
Neutron star Interior Composition Explorer (NICER)
2017-12-08
A NICER team member measures the focused optical power of each X-ray concentrator in a clean tent at NASA’s Goddard Space Flight Center. The Neutron star Interior Composition Explorer (NICER) is a NASA Explorer Mission of Opportunity dedicated to studying the extraordinary environments — strong gravity, ultra-dense matter, and the most powerful magnetic fields in the universe — embodied by neutron stars. An attached payload aboard the International Space Station, NICER will deploy an instrument with unique capabilities for timing and spectroscopy of fast X-ray brightness fluctuations. The embedded Station Explorer for X-ray Timing and Navigation Technology demonstration (SEXTANT) will use NICER data to validate, for the first time in space, technology that exploits pulsars as natural navigation beacons. Credit: NASA/Goddard/ Keith Gendreau NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram
Justice and health care: When “ordinary” is extraordinary†
McTavish, James
2016-01-01
In some Asian countries, the poor are often denied access to health care. In the Philippines, we have thousands of Catholic doctors, Catholic nurses, even Catholic administrators, but not a Catholic, understood as “universal,” healthcare system available to all. This is a scandal and places heavy emotional and financial burdens on many families who need to pay the healthcare costs of sick loved ones. The Church teaches the principles of ordinary and extraordinary care, with only the former being morally obligatory. Extraordinary care, that involving excessive burden or cost may be foregone. Many families and healthcare professionals are uncertain about these principles and their application in practice. It would be helpful to more widely disseminate the Catholic Church teaching regarding ordinary and extraordinary care, especially in poor countries, to also avoid unnecessary or futile treatments, especially in critical or end-of-life situations. Lay Summary: The poor have limited access to health care in many countries. Even one episode of sickness often places the patient and their family under considerable financial strain. Many times they simply cannot afford even basic treatments. This is a scandal and an injustice which is the concern of us all. The Church teaches that when a treatment becomes very expensive it may be considered “extraordinary care” and not morally obligatory. It would be helpful to more widely disseminate this Catholic Church teaching, helping families to avoid unnecessary treatments especially in critical or end-of-life situations. PMID:27833180
Semantics of the visual environment encoded in parahippocampal cortex
Bonner, Michael F.; Price, Amy Rose; Peelle, Jonathan E.; Grossman, Murray
2016-01-01
Semantic representations capture the statistics of experience and store this information in memory. A fundamental component of this memory system is knowledge of the visual environment, including knowledge of objects and their associations. Visual semantic information underlies a range of behaviors, from perceptual categorization to cognitive processes such as language and reasoning. Here we examine the neuroanatomic system that encodes visual semantics. Across three experiments, we found converging evidence indicating that knowledge of verbally mediated visual concepts relies on information encoded in a region of the ventral-medial temporal lobe centered on parahippocampal cortex. In an fMRI study, this region was strongly engaged by the processing of concepts relying on visual knowledge but not by concepts relying on other sensory modalities. In a study of patients with the semantic variant of primary progressive aphasia (semantic dementia), atrophy that encompassed this region was associated with a specific impairment in verbally mediated visual semantic knowledge. Finally, in a structural study of healthy adults from the fMRI experiment, gray matter density in this region related to individual variability in the processing of visual concepts. The anatomic location of these findings aligns with recent work linking the ventral-medial temporal lobe with high-level visual representation, contextual associations, and reasoning through imagination. Together this work suggests a critical role for parahippocampal cortex in linking the visual environment with knowledge systems in the human brain. PMID:26679216
Semantics of the Visual Environment Encoded in Parahippocampal Cortex.
Bonner, Michael F; Price, Amy Rose; Peelle, Jonathan E; Grossman, Murray
2016-03-01
Semantic representations capture the statistics of experience and store this information in memory. A fundamental component of this memory system is knowledge of the visual environment, including knowledge of objects and their associations. Visual semantic information underlies a range of behaviors, from perceptual categorization to cognitive processes such as language and reasoning. Here we examine the neuroanatomic system that encodes visual semantics. Across three experiments, we found converging evidence indicating that knowledge of verbally mediated visual concepts relies on information encoded in a region of the ventral-medial temporal lobe centered on parahippocampal cortex. In an fMRI study, this region was strongly engaged by the processing of concepts relying on visual knowledge but not by concepts relying on other sensory modalities. In a study of patients with the semantic variant of primary progressive aphasia (semantic dementia), atrophy that encompassed this region was associated with a specific impairment in verbally mediated visual semantic knowledge. Finally, in a structural study of healthy adults from the fMRI experiment, gray matter density in this region related to individual variability in the processing of visual concepts. The anatomic location of these findings aligns with recent work linking the ventral-medial temporal lobe with high-level visual representation, contextual associations, and reasoning through imagination. Together, this work suggests a critical role for parahippocampal cortex in linking the visual environment with knowledge systems in the human brain.
High visual resolution matters in audiovisual speech perception, but only for some.
Alsius, Agnès; Wayne, Rachel V; Paré, Martin; Munhall, Kevin G
2016-07-01
The basis for individual differences in the degree to which visual speech input enhances comprehension of acoustically degraded speech is largely unknown. Previous research indicates that fine facial detail is not critical for visual enhancement when auditory information is available; however, these studies did not examine individual differences in ability to make use of fine facial detail in relation to audiovisual speech perception ability. Here, we compare participants based on their ability to benefit from visual speech information in the presence of an auditory signal degraded with noise, modulating the resolution of the visual signal through low-pass spatial frequency filtering and monitoring gaze behavior. Participants who benefited most from the addition of visual information (high visual gain) were more adversely affected by the removal of high spatial frequency information, compared to participants with low visual gain, for materials with both poor and rich contextual cues (i.e., words and sentences, respectively). Differences as a function of gaze behavior between participants with the highest and lowest visual gains were observed only for words, with participants with the highest visual gain fixating longer on the mouth region. Our results indicate that the individual variance in audiovisual speech in noise performance can be accounted for, in part, by better use of fine facial detail information extracted from the visual signal and increased fixation on mouth regions for short stimuli. Thus, for some, audiovisual speech perception may suffer when the visual input (in addition to the auditory signal) is less than perfect.
Program Annual Technology Report: Physics of the Cosmos Program Office
NASA Technical Reports Server (NTRS)
Pham, Bruce Thai; Cardiff, Ann H.
2017-01-01
From ancient times, humans have looked up at the night sky and wondered: Are we alone? How did the universe come to be? How does the universe work? PCOS focuses on that last question. Scientists investigating this broad theme use the universe as their laboratory, investigating its fundamental laws and properties. They test Einstein’s General Theory of Relativity to see if our current understanding of space-time is borne out by observations. They examine the behavior of the most extreme environments – supermassive black holes, active galactic nuclei, and others – and the farthest reaches of the universe, to expand our understanding. With instruments sensitive across the spectrum, from radio, through infrared (IR), visible light, ultraviolet (UV), to X rays and gamma rays, as well as gravitational waves (GWs), they peer across billions of light-years, observing echoes of events that occurred instants after the Big Bang. Last year, the LISA Pathfinder (LPF) mission exceeded expectations in proving the maturity of technologies needed for the Laser Interferometer Space Antenna (LISA) mission, and the Laser Interferometer Gravitational-Wave Observatory (LIGO) recorded the first direct measurements of long-theorized GWs. Another surprising recent discovery is that the universe is expanding at an ever-accelerating rate, the first hint of so-called “dark energy,” estimated to account for 75% of mass-energy in the universe. Dark matter, so called because we can only observe its effects on regular matter, is thought to account for another20%, leaving only 5% for regular matter and energy. Scientists now also search for special polarization in the cosmic microwave background to support the notion that in the split-second after the Big Bang, the universe inflated faster than the speed of light! The most exciting aspect of this grand enterprise today is the extraordinary rate at which we can harness technologies to enable these key discoveries.
USDA-ARS?s Scientific Manuscript database
Vegetative Environmental Buffers (VEBs) are vegetation designed as a visual screen, which usually consist of trees, shrubs, grass and other potential plants. VEBs are placed around the poultry houses for the purpose of minimizing the air pollutant emissions. The expansion of the poultry industry due...
Challenging Popular Media's Control by Teaching Critical Viewing.
ERIC Educational Resources Information Center
Couch, Richard A.
The purpose of this paper is to express the importance of visual/media literacy and the teaching of critical television viewing. An awareness of the properties and characteristics of television--including camera angles and placement, editing, and emotionally involving subject matter--aids viewers in the critical viewing process. The knowledge of…
Science Photo of person viewing 3D visualization of a wind turbine The NREL Computational Science challenges in fields ranging from condensed matter physics and nonlinear dynamics to computational fluid dynamics. NREL is also home to the most energy-efficient data center in the world, featuring Peregrine-the
Pattern Perception and Pictures for the Blind
ERIC Educational Resources Information Center
Heller, Morton A.; McCarthy, Melissa; Clark, Ashley
2005-01-01
This article reviews recent research on perception of tangible pictures in sighted and blind people. Haptic picture naming accuracy is dependent upon familiarity and access to semantic memory, just as in visual recognition. Performance is high when haptic picture recognition tasks do not depend upon semantic memory. Viewpoint matters for the ease…
40 CFR 63.7330 - What are my monitoring requirements?
Code of Federal Regulations, 2010 CFR
2010-07-01
... relative change in particulate matter loadings using a bag leak detection system according to the... integrity of the baghouse through quarterly visual inspections of the baghouse interior for air leaks; and... must at all times monitor the pressure drop and water flow rate using a CPMS according to the...
78 FR 19326 - Resale Royalty Right; Public Hearing
Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-29
... is reviewing: (1) how the current copyright legal system affects and supports visual artists; and (2... interested parties to address the legal and factual questions raised in the comments received by this Office... parties. The comments raised a variety of issues, including purely legal matters as well as specific...
Ouachita and Ozark Mountains symposium: ecosystem management research
James M. Guldin
2004-01-01
This volume presents 5-year results of silvicultural treatments associated with ecosystem management research in the Ouachita Mountains of Arkansas. Results from stand-level treatments include regeneration dynamics of pine and hardwood species, effects of treatment on birds and small mammals, mast production, visual quality, oak decline, and organic matter....
Environmental Inversion Effects in Face Perception
ERIC Educational Resources Information Center
Davidenko, Nicolas; Flusberg, Stephen J.
2012-01-01
Visual processing is highly sensitive to stimulus orientation; for example, face perception is drastically worse when faces are oriented inverted vs. upright. However, stimulus orientation must be established in relation to a particular reference frame, and in most studies, several reference frames are conflated. Which reference frame(s) matter in…
Student Preferences for Online Lecture Formats: Does Prior Experience Matter?
ERIC Educational Resources Information Center
Drouin, Michelle; Hile, Rachel E.; Vartanian, Lesa R.; Webb, Janae
2013-01-01
We examined undergraduate students' quality ratings of and preferences for different types of online lecture formats. Students preferred richer online lecture formats that included both audio and visual components; however, there were no significant differences between students' ratings of PowerPoint lectures with "audio" of the…
An Arts Activities Approach: Counseling the Gifted, Creative, and Talented.
ERIC Educational Resources Information Center
Kenny, Adele
1987-01-01
The visual arts can be employed as a counseling vehicle for gifted, creative, and talented students. Color, image proportion, subject matter, and texture in student art facilitate assessment and guidance. Craft, drawing, painting, photography, printing, design, and sculpture activities which could help in this process are briefly described. (CB)
Paneling "Matters" in Elementary Students' Graphic Narratives
ERIC Educational Resources Information Center
Pantaleo, Sylvia
2013-01-01
During a 10-week classroom-based study, 20 fourth grade students participated in a number of interdependent activities that focused on developing their visual meaning-making skills and competencies. As well as reading, responding in writing to and discussing a selection of picturebooks, graphic novels, and magazines, the students created graphic…
Right Temporoparietal Gray Matter Predicts Accuracy of Social Perception in the Autism Spectrum
ERIC Educational Resources Information Center
David, Nicole; Schultz, Johannes; Milne, Elizabeth; Schunke, Odette; Schöttle, Daniel; Münchau, Alexander; Siegel, Markus; Vogeley, Kai; Engel, Andreas K.
2014-01-01
Individuals with an autism spectrum disorder (ASD) show hallmark deficits in social perception. These difficulties might also reflect fundamental deficits in integrating visual signals. We contrasted predictions of a social perception and a spatial-temporal integration deficit account. Participants with ASD and matched controls performed two…
ERIC Educational Resources Information Center
Hodges, Bert H.
2007-01-01
Ecological approaches (e.g. [Gibson, J.J., 1979. "The Ecological Approach to Visual Perception." Houghton-Mifflin, Boston]) to psychology and language are selectively reviewed, focusing on social learning. Is social learning (e.g., acquiring language) a matter of conformity [Tomasello, M., 2006. "Acquiring linguistic…
Hierarchical streamline bundles.
Yu, Hongfeng; Wang, Chaoli; Shene, Ching-Kuang; Chen, Jacqueline H
2012-08-01
Effective 3D streamline placement and visualization play an essential role in many science and engineering disciplines. The main challenge for effective streamline visualization lies in seed placement, i.e., where to drop seeds and how many seeds should be placed. Seeding too many or too few streamlines may not reveal flow features and patterns either because it easily leads to visual clutter in rendering or it conveys little information about the flow field. Not only does the number of streamlines placed matter, their spatial relationships also play a key role in understanding the flow field. Therefore, effective flow visualization requires the streamlines to be placed in the right place and in the right amount. This paper introduces hierarchical streamline bundles, a novel approach to simplifying and visualizing 3D flow fields defined on regular grids. By placing seeds and generating streamlines according to flow saliency, we produce a set of streamlines that captures important flow features near critical points without enforcing the dense seeding condition. We group spatially neighboring and geometrically similar streamlines to construct a hierarchy from which we extract streamline bundles at different levels of detail. Streamline bundles highlight multiscale flow features and patterns through clustered yet not cluttered display. This selective visualization strategy effectively reduces visual clutter while accentuating visual foci, and therefore is able to convey the desired insight into the flow data.
Audio-video decision support for patients: the documentary genré as a basis for decision aids.
Volandes, Angelo E; Barry, Michael J; Wood, Fiona; Elwyn, Glyn
2013-09-01
Decision support tools are increasingly using audio-visual materials. However, disagreement exists about the use of audio-visual materials as they may be subjective and biased. This is a literature review of the major texts for documentary film studies to extrapolate issues of objectivity and bias from film to decision support tools. The key features of documentary films are that they attempt to portray real events and that the attempted reality is always filtered through the lens of the filmmaker. The same key features can be said of decision support tools that use audio-visual materials. Three concerns arising from documentary film studies as they apply to the use of audio-visual materials in decision support tools include whose perspective matters (stakeholder bias), how to choose among audio-visual materials (selection bias) and how to ensure objectivity (editorial bias). Decision science needs to start a debate about how audio-visual materials are to be used in decision support tools. Simply because audio-visual materials may be subjective and open to bias does not mean that we should not use them. Methods need to be found to ensure consensus around balance and editorial control, such that audio-visual materials can be used. © 2011 John Wiley & Sons Ltd.
Audio‐video decision support for patients: the documentary genré as a basis for decision aids
Volandes, Angelo E.; Barry, Michael J.; Wood, Fiona; Elwyn, Glyn
2011-01-01
Abstract Objective Decision support tools are increasingly using audio‐visual materials. However, disagreement exists about the use of audio‐visual materials as they may be subjective and biased. Methods This is a literature review of the major texts for documentary film studies to extrapolate issues of objectivity and bias from film to decision support tools. Results The key features of documentary films are that they attempt to portray real events and that the attempted reality is always filtered through the lens of the filmmaker. The same key features can be said of decision support tools that use audio‐visual materials. Three concerns arising from documentary film studies as they apply to the use of audio‐visual materials in decision support tools include whose perspective matters (stakeholder bias), how to choose among audio‐visual materials (selection bias) and how to ensure objectivity (editorial bias). Discussion Decision science needs to start a debate about how audio‐visual materials are to be used in decision support tools. Simply because audio‐visual materials may be subjective and open to bias does not mean that we should not use them. Conclusion Methods need to be found to ensure consensus around balance and editorial control, such that audio‐visual materials can be used. PMID:22032516
White matter injury detection in neonatal MRI
NASA Astrophysics Data System (ADS)
Cheng, Irene; Hajari, Nasim; Firouzmanesh, Amirhossein; Shen, Rui; Miller, Steven; Poskitt, Ken; Basu, Anup
2013-02-01
Early detection of white matter injury in premature newborns can facilitate timely clinical treatments reducing the potential risk of later developmental deficits. It was reported that there were more than 5% premature newborns in British Columbia, Canada, among which 5-10% exhibited major motor deficits and 25-50% exhibited significant developmental and visual deficits. With the advancement of computer assisted detection systems, it is possible to automatically identify white matter injuries, which are found inside the grey matter region of the brain. Atlas registration has been suggested in the literature to distinguish grey matter from the soft tissues inside the skull. However, our subjects are premature newborns delivered at 24 to 32 weeks of gestation. During this period, the grey matter undergoes rapid changes and differs significantly from one to another. Besides, not all detected white spots represent injuries. Additional neighborhood information and expert input are required for verification. In this paper, we propose a white matter feature identification system for premature newborns, which is composed of several steps: (1) Candidate white matter segmentation; (2) Feature extraction from candidates; (3) Validation with data obtained at a later stage on the children; and (4) Feature confirmation for automated detection. The main challenge of this work lies in segmenting white matter injuries from noisy and low resolution data. Our approach integrates image fusion and contrast enhancement together with a fuzzy segmentation technique to achieve promising results. Other applications, such as brain tumor and intra-ventricular haemorrhage detection can also benefit from our approach.
Neuroanatomy: The added value of the Klingler method.
Silva, Susana M; Andrade, José Paulo
2016-11-01
Undergraduate neuroanatomy students are usually not able to achieve a clear comprehension of the spatial relationships existing between the white matter fiber tracts in spite of numerous neuroanatomy textbooks, atlases and multimedia tools. The objective of this paper is to show the educational value of the application of the Klingler fiber dissection technique and the use of these dissections in the understanding of the three-dimensional intrinsic anatomy of the brain white matter for medical students. Four formalin-fixed brains were dissected using the Klingler methodology in order to reveal the inner anatomical organization of the brain white matter. The most important fiber systems were dissected and their relationships to the cerebral and cerebellar gray matter structures visualized. These dissections were used as a learning tool in teaching the brain white matter structural and topographical connectivity. The white matter fiber systems were presented to undergraduate medical students during a neuroanatomy course. They observed and manipulated the dissected specimens leading to a thorough understanding of the configuration and location of the white matter fiber tracts, and their relationships to the ventricular system and gray matter structures. Subsequently, students were asked to answer a survey concerning the importance of the utilization of this material in their understanding of the three-dimensional intrinsic anatomy of the brain white matter. The knowledge acquired with this technique, complemented by conventional formalin-fixed sections may improve the neuroanatomical knowledge and future retention of medical students. Copyright © 2016 Elsevier GmbH. All rights reserved.
Warner, Tamara Duckworth; Behnke, Marylou; Eyler, Fonda Davis; Padgett, Kyle; Leonard, Christiana; Hou, Wei; Garvan, Cynthia Wilson; Schmalfuss, Ilona M.; Blackband, Stephen J.
2011-01-01
BACKGROUND Although animal studies have demonstrated frontal white matter and behavioral changes resulting from prenatal cocaine exposure, no human studies have associated neuropsychological deficits in attention and inhibition with brain structure. We used diffusion tensor imaging to investigate frontal white matter integrity and executive functioning in cocaine-exposed children. METHODS Six direction diffusion tensor images were acquired using a Siemens 3T scanner with a spin-echo echo-planar imaging pulse sequence on right-handed cocaine-exposed (n = 28) and sociodemographically similar non-exposed children (n = 25; mean age: 10.6 years) drawn from a prospective, longitudinal study. Average diffusion and fractional anisotropy were measured in the left and right frontal callosal and frontal projection fibers. Executive functioning was assessed using two well-validated neuropsychological tests (Stroop color-word test and Trail Making Test). RESULTS Cocaine-exposed children showed significantly higher average diffusion in the left frontal callosal and right frontal projection fibers. Cocaine-exposed children were also significantly slower on a visual-motor set-shifting task with a trend toward lower scores on a verbal inhibition task. Controlling for gender and intelligence, average diffusion in the left frontal callosal fibers was related to prenatal exposure to alcohol and marijuana and an interaction between cocaine and marijuana exposure. Performance on the visual-motor set-shifting task was related to prenatal cocaine exposure and an interaction between cocaine and tobacco exposure. Significant correlations were found between test performance and fractional anisotropy in areas of the frontal white matter. CONCLUSIONS Prenatal cocaine exposure, alone and in combination with exposure to other drugs, is associated with slightly poorer executive functioning and subtle microstructural changes suggesting less mature development of frontal white matter pathways. The relative contribution of postnatal environmental factors, including characteristics of the caregiving environment and stressors associated with poverty and out-of-home placement, on brain development and behavioral functioning in polydrug-exposed children awaits further research. PMID:17079574
Warner, Tamara Duckworth; Behnke, Marylou; Eyler, Fonda Davis; Padgett, Kyle; Leonard, Christiana; Hou, Wei; Garvan, Cynthia Wilson; Schmalfuss, Ilona M; Blackband, Stephen J
2006-11-01
Although animal studies have demonstrated frontal white matter and behavioral changes resulting from prenatal cocaine exposure, no human studies have associated neuropsychological deficits in attention and inhibition with brain structure. We used diffusion tensor imaging to investigate frontal white matter integrity and executive functioning in cocaine-exposed children. Six direction diffusion tensor images were acquired using a Siemens 3T scanner with a spin-echo echo-planar imaging pulse sequence on right-handed cocaine-exposed (n = 28) and sociodemographically similar non-exposed children (n = 25; mean age: 10.6 years) drawn from a prospective, longitudinal study. Average diffusion and fractional anisotropy were measured in the left and right frontal callosal and frontal projection fibers. Executive functioning was assessed using two well-validated neuropsychological tests (Stroop color-word test and Trail Making Test). Cocaine-exposed children showed significantly higher average diffusion in the left frontal callosal and right frontal projection fibers. Cocaine-exposed children were also significantly slower on a visual-motor set-shifting task with a trend toward lower scores on a verbal inhibition task. Controlling for gender and intelligence, average diffusion in the left frontal callosal fibers was related to prenatal exposure to alcohol and marijuana and an interaction between cocaine and marijuana exposure. Performance on the visual-motor set-shifting task was related to prenatal cocaine exposure and an interaction between cocaine and tobacco exposure. Significant correlations were found between test performance and fractional anisotropy in areas of the frontal white matter. Prenatal cocaine exposure, alone and in combination with exposure to other drugs, is associated with slightly poorer executive functioning and subtle microstructural changes suggesting less mature development of frontal white matter pathways. The relative contribution of postnatal environmental factors, including characteristics of the caregiving environment and stressors associated with poverty and out-of-home placement, on brain development and behavioral functioning in polydrug-exposed children awaits further research.
NASA Astrophysics Data System (ADS)
Chen, Jianjun; Ying, Qi; Kleeman, Michael J.
2009-12-01
Gases and particulate matter predictions from the UCD/CIT air quality model were used in a visibility model to predict source contributions to visual impairment in the San Joaquin Valley (SJV), the southern portion of California's Central Valley, during December 2000 and January 2001. Within the SJV, daytime (0800-1700 PST) light extinction was dominated by scattering associated with airborne particles. Measured daytime particle scattering coefficients were compared to predicted values at approximately 40 locations across the SJV after correction for the increased temperature and decreased relative humidity produced by "smart heaters" placed upstream of nephelometers. Mean fractional bias and mean fractional error were -0.22 and 0.65, respectively, indicating reasonable agreement between model predictions and measurements. Particulate water, nitrate, organic matter, and ammonium were the major particulate species contributing to light scattering in the SJV. Daytime light extinction in the SJV averaged between December 25, 2000 and January 7, 2001 was mainly associated with animal ammonia sources (28%), diesel engines (18%), catalyst gasoline engines (9%), other anthropogenic sources (9%), and wood smoke (7%) with initial and boundary conditions accounting for 13%. The source apportionment results from this study apply to wintertime conditions when airborne particulate matter concentrations are typically at their annual maximum. Further study would be required to quantify source contributions to light extinction in other seasons.
Weerasekara, Gihan; Tokunaga, Akihiro; Terauchi, Hiroki; Eberhard, Marc; Maruta, Akihiro
2015-01-12
One of the extraordinary aspects of nonlinear wave evolution which has been observed as the spontaneous occurrence of astonishing and statistically extraordinary amplitude wave is called rogue wave. We show that the eigenvalues of the associated equation of nonlinear Schrödinger equation are almost constant in the vicinity of rogue wave and we validate that optical rogue waves are formed by the collision between quasi-solitons in anomalous dispersion fiber exhibiting weak third order dispersion.
NASA Astrophysics Data System (ADS)
Noureen, S.; Abbas, G.; Sarfraz, M.
2018-01-01
The study of relativistic degenerate plasmas is important in many astrophysical and laboratory environments. Using linearized relativistic Vlasov-Maxwell equations, a generalized expression for the plasma conductivity tensor is derived. Employing Fermi-Dirac distribution at zero temperature, the dispersion relation of the extraordinary mode in a relativistic degenerate electron plasma is investigated. The propagation characteristics are examined in different relativistic density ranges. The shifting of cutoff points due to relativistic effects is observed analytically and graphically. Non-relativistic and ultra-relativistic limiting cases are also presented.
NASA Astrophysics Data System (ADS)
Koryagin, S. A.
2015-06-01
We showed that, in the photosphere of a white dwarf with strong magnetic field, the collisional absorption significantly decreases at the frequencies below the electron cyclotron frequency for the electromagnetic waves linearly polarized across the magnetic field lines (for the so-called extraordinary waves in a magnetized plasma). As a result, the extraordinary waves can escape from the deeper and hotter photosphere layers than the ordinary waves and, in this way, can determine the high linear polarization at the infrared and optical continuum.
Maestas, Gabrielle; Hu, Jiyao; Trevino, Jessica; Chunduru, Pranathi; Kim, Seung-Jae; Lee, Hyunglae
2018-01-01
The use of visual feedback in gait rehabilitation has been suggested to promote recovery of locomotor function by incorporating interactive visual components. Our prior work demonstrated that visual feedback distortion of changes in step length symmetry entails an implicit or unconscious adaptive process in the subjects’ spatial gait patterns. We investigated whether the effect of the implicit visual feedback distortion would persist at three different walking speeds (slow, self-preferred and fast speeds) and how different walking speeds would affect the amount of adaption. In the visual feedback distortion paradigm, visual vertical bars portraying subjects’ step lengths were distorted so that subjects perceived their step lengths to be asymmetric during testing. Measuring the adjustments in step length during the experiment showed that healthy subjects made spontaneous modulations away from actual symmetry in response to the implicit visual distortion, no matter the walking speed. In all walking scenarios, the effects of implicit distortion became more significant at higher distortion levels. In addition, the amount of adaptation induced by the visual distortion was significantly greater during walking at preferred or slow speed than at the fast speed. These findings indicate that although a link exists between supraspinal function through visual system and human locomotion, sensory feedback control for locomotion is speed-dependent. Ultimately, our results support the concept that implicit visual feedback can act as a dominant form of feedback in gait modulation, regardless of speed. PMID:29632481
Fritz, Jonathan B.; Malloy, Megan; Mishkin, Mortimer; Saunders, Richard C.
2016-01-01
While monkeys easily acquire the rules for performing visual and tactile delayed matching-to-sample, a method for testing recognition memory, they have extraordinary difficulty acquiring a similar rule in audition. Another striking difference between the modalities is that whereas bilateral ablation of the rhinal cortex (RhC) leads to profound impairment in visual and tactile recognition, the same lesion has no detectable effect on auditory recognition memory (Fritz et al., 2005). In our previous study, a mild impairment in auditory memory was obtained following bilateral ablation of the entire medial temporal lobe (MTL), including the RhC, and an equally mild effect was observed after bilateral ablation of the auditory cortical areas in the rostral superior temporal gyrus (rSTG). In order to test the hypothesis that each of these mild impairments was due to partial disconnection of acoustic input to a common target (e.g., the ventromedial prefrontal cortex), in the current study we examined the effects of a more complete auditory disconnection of this common target by combining the removals of both the rSTG and the MTL. We found that the combined lesion led to forgetting thresholds (performance at 75% accuracy) that fell precipitously from the normal retention duration of ~30–40 seconds to a duration of ~1–2 seconds, thus nearly abolishing auditory recognition memory, and leaving behind only a residual echoic memory. PMID:26707975