KSC-08pd2383

NASA Image and Video Library

2008-08-12

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, the cover of the Wide Field Camera 3, or WFC3, shipping container is lifted away from the mobile base. As Hubble enters the last stage of its life, WFC3 will be Hubble's next evolutionary step, allowing Hubble to peer ever further into the mysteries of the cosmos. WFC3 will study a diverse range of objects and phenomena, from young and extremely distant galaxies, to much more nearby stellar systems, to objects within our very own solar system. WFC3 will take the place of Wide Field Planetary Camera 2, which astronauts will bring back to Earth aboard the shuttle. WFC3 is part of the payload on the fifth and final Hubble servicing mission, STS-125, targeted for launch Oct. 8. Photo credit: NASA/Jack Pfaller

KSC-08pd2392

NASA Image and Video Library

2008-08-12

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, technicians move the base of the shipping container holding the Wide Field Camera 3, or WFC3, into the high bay. As Hubble enters the last stage of its life, WFC3 will be Hubble's next evolutionary step, allowing Hubble to peer ever further into the mysteries of the cosmos. WFC3 will study a diverse range of objects and phenomena, from young and extremely distant galaxies, to much more nearby stellar systems, to objects within our very own solar system. WFC3 will take the place of Wide Field Planetary Camera 2, which astronauts will bring back to Earth aboard the shuttle. WFC3 is part of the payload on the fifth and final Hubble servicing mission, STS-125, targeted for launch Oct. 8. Photo credit: NASA/Jack Pfaller

KSC-08pd2391

NASA Image and Video Library

2008-08-12

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, technicians move the base of the shipping container holding the Wide Field Camera 3, or WFC3. As Hubble enters the last stage of its life, WFC3 will be Hubble's next evolutionary step, allowing Hubble to peer ever further into the mysteries of the cosmos. WFC3 will study a diverse range of objects and phenomena, from young and extremely distant galaxies, to much more nearby stellar systems, to objects within our very own solar system. WFC3 will take the place of Wide Field Planetary Camera 2, which astronauts will bring back to Earth aboard the shuttle. WFC3 is part of the payload on the fifth and final Hubble servicing mission, STS-125, targeted for launch Oct. 8. Photo credit: NASA/Jack Pfaller

KSC-08pd2398

NASA Image and Video Library

2008-08-12

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, technicians monitor the placement of the Wide Field Camera 3, or WFC3, on a work stand. As Hubble enters the last stage of its life, WFC3 will be Hubble's next evolutionary step, allowing Hubble to peer ever further into the mysteries of the cosmos. WFC3 will study a diverse range of objects and phenomena, from young and extremely distant galaxies, to much more nearby stellar systems, to objects within our very own solar system. WFC3 will take the place of Wide Field Planetary Camera 2, which astronauts will bring back to Earth aboard the shuttle. WFC3 is part of the payload on the fifth and final Hubble servicing mission, STS-125, targeted for launch Oct. 8. Photo credit: NASA/Jack Pfaller

KSC-08pd2450

NASA Image and Video Library

2008-08-16

CAPE CANAVERAL, Fla. – Technicians in the Payload Hazardous Servicing Facility remove the protective cover from the Wide Field Camera 3, or WFC3. The WFC3 is part of the payload on space shuttle Atlantis for the fifth and final Hubble servicing mission, STS-125. As Hubble enters the last stage of its life, WFC3 will be Hubble's next evolutionary step, allowing Hubble to peer ever further into the mysteries of the cosmos. WFC3 will study a diverse range of objects and phenomena, from young and extremely distant galaxies, to much more nearby stellar systems, to objects within our very own solar system. WFC3 will take the place of Wide Field Planetary Camera 2, which astronauts will bring back to Earth aboard the shuttle. Launch of Atlantis is targeted at 1:34 a.m. EDT Oct. 8. Photo credit: NASA/Jack Pfaller

KSC-08pd2381

NASA Image and Video Library

2008-08-12

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, technicians attach an overhead crane to the cover of the Wide Field Camera 3, or WFC3, shipping container. As Hubble enters the last stage of its life, WFC3 will be Hubble's next evolutionary step, allowing Hubble to peer ever further into the mysteries of the cosmos. WFC3 will study a diverse range of objects and phenomena, from young and extremely distant galaxies, to much more nearby stellar systems, to objects within our very own solar system. WFC3 will take the place of Wide Field Planetary Camera 2, which astronauts will bring back to Earth aboard the shuttle. WFC3 is part of the payload on the fifth and final Hubble servicing mission, STS-125, targeted for launch Oct. 8. Photo credit: NASA/Jack Pfaller

KSC-08pd2449

NASA Image and Video Library

2008-08-16

CAPE CANAVERAL, Fla. – Technicians in the Payload Hazardous Servicing Facility begin removing the protective cover from the Wide Field Camera 3, or WFC3. The WFC3 is part of the payload on space shuttle Atlantis for the fifth and final Hubble servicing mission, STS-125. As Hubble enters the last stage of its life, WFC3 will be Hubble's next evolutionary step, allowing Hubble to peer ever further into the mysteries of the cosmos. WFC3 will study a diverse range of objects and phenomena, from young and extremely distant galaxies, to much more nearby stellar systems, to objects within our very own solar system. WFC3 will take the place of Wide Field Planetary Camera 2, which astronauts will bring back to Earth aboard the shuttle. Launch of Atlantis is targeted at 1:34 a.m. EDT Oct. 8. Photo credit: NASA/Jack Pfaller

KSC-08pd2378

NASA Image and Video Library

2008-08-12

CAPE CANAVERAL, Fla. – The shipping container with the Wide Field Camera 3, or WFC3, inside is removed from the truck outside the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center. As Hubble enters the last stage of its life, WFC3 will be Hubble's next evolutionary step, allowing Hubble to peer ever further into the mysteries of the cosmos. WFC3 will study a diverse range of objects and phenomena, from young and extremely distant galaxies, to much more nearby stellar systems, to objects within our very own solar system. WFC3 will take the place of Wide Field Planetary Camera 2, which astronauts will bring back to Earth aboard the shuttle. WFC3 is part of the payload on the fifth and final Hubble servicing mission, STS-125, targeted for launch Oct. 8. Photo credit: NASA/Jack Pfaller

KSC-08pd2382

NASA Image and Video Library

2008-08-12

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, technicians begin lifting the cover of the Wide Field Camera 3, or WFC3, shipping container. As Hubble enters the last stage of its life, WFC3 will be Hubble's next evolutionary step, allowing Hubble to peer ever further into the mysteries of the cosmos. WFC3 will study a diverse range of objects and phenomena, from young and extremely distant galaxies, to much more nearby stellar systems, to objects within our very own solar system. WFC3 will take the place of Wide Field Planetary Camera 2, which astronauts will bring back to Earth aboard the shuttle. WFC3 is part of the payload on the fifth and final Hubble servicing mission, STS-125, targeted for launch Oct. 8. Photo credit: NASA/Jack Pfaller

KSC-08pd2379

NASA Image and Video Library

2008-08-12

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, technicians unlatch the cover of the Wide Field Camera 3, or WFC3,shipping container before removing it. As Hubble enters the last stage of its life, WFC3 will be Hubble's next evolutionary step, allowing Hubble to peer ever further into the mysteries of the cosmos. WFC3 will study a diverse range of objects and phenomena, from young and extremely distant galaxies, to much more nearby stellar systems, to objects within our very own solar system. WFC3 will take the place of Wide Field Planetary Camera 2, which astronauts will bring back to Earth aboard the shuttle. WFC3 is part of the payload on the fifth and final Hubble servicing mission, STS-125, targeted for launch Oct. 8. Photo credit: NASA/Jack Pfaller

Engaging in extreme activism in support of others’ political struggles: The role of politically motivated fusion with out-groups

PubMed Central

Boos, Beverly; Kimel, Sasha Y.; Obaidi, Milan; Shani, Maor; Thomsen, Lotte

2018-01-01

Humans are a coalitional, parochial species. Yet, extreme actions of solidarity are sometimes taken for distant or unrelated groups. What motivates people to become solidary with groups to which they do not belong originally? Here, we demonstrate that such distant solidarity can occur when the perceived treatment of an out-group clashes with one’s political beliefs (e.g., for Leftists, oppressive occupation of the out-group) and that it is driven by fusion (or a feeling of oneness) with distant others with whom one does not share any common social category such as nationality, ethnicity or religion. In Study 1, being politically Leftist predicted European-Americans’ willingness to engage in extreme protest on behalf of Palestinians, which was mediated by fusion with the out-group. Next, in Study 2, we examined whether this pattern was moderated by out-group type. Here, Norwegian Leftists fused more with Palestinians (i.e., a group that, in the Norwegian context, is perceived to be occupied in an asymmetrical conflict) rather than Kurds (i.e., a group for which this perception is less salient). In Study 3, we experimentally tested the underlying mechanism by framing the Kurdish conflict in terms of an asymmetrical occupation (vs. symmetrical war or control conditions) and found that this increased Leftist European-Americans’ fusion with Kurds. Finally, in Study 4, we used a unique sample of non-Kurdish aspiring foreign fighters who were in the process of joining the Kurdish militia YPG. Here, fusion with the out-group predicted a greater likelihood to join and support the Kurdish forces in their fight against ISIS, insofar as respondents experienced that their political orientation morally compelled them to do so (Study 4). Together, our findings suggest that politically motivated fusion with out-groups underpins the extreme solidary action people may take on behalf of distant out-groups. Implications for future theory and research are discussed. PMID:29304156

Influencing Attitudes Toward Near and Distant Objects

PubMed Central

Fujita, Kentaro; Eyal, Tal; Chaiken, Shelly; Trope, Yaacov; Liberman, Nira

2008-01-01

It is argued that the temporal distance of attitude objects systematically changes how the object is mentally represented, and thus influences the strength of particular persuasive appeals. Three experiments tested the hypothesis that people preferentially attend to arguments that highlight primary, abstract (high-level) vs. incidental, concrete (low-level) features when attitude objects are temporally distant vs. near. Results suggested that when attitude objects are temporally distant vs. near, arguments emphasizing primary vs. secondary features (Study 1), desirability vs. feasibility features (Study 2), and general classes vs. specific cases are more persuasive (Study 3). The relation of construal theory to dual process theories of persuasion and persuasion phenomena, such as personal relevance effects and functional matching effects, are discussed. PMID:19884971

CFHT and VLT Identify Extremely Remote Galaxy

NASA Astrophysics Data System (ADS)

2003-05-01

Top Telescopes Peer into the Distant Past Summary With improved telescopes and instruments, observations of extremely remote and faint galaxies have become possible that were until recently astronomers' dreams. One such object was found by a team of astronomers [2] with a wide-field camera installed at the Canada-France-Hawaii telescope at Mauna Kea (Hawaii, USA) during a search for extremely distant galaxies. Designated "z6VDF J022803-041618" , it was detected because of its unusual colour , being visible only on images obtained through a special optical filter isolating light in a narrow near-infrared band. A follow-up spectrum of this object with the FORS2 multi-mode instrument at the ESO Very Large Telescope (VLT) confirmed that it is a very distant galaxy (the redshift is 6.17 [3]). It is seen as it was when the Universe was only about 900 million years old . z6VDF J022803-041618 is one of the most distant galaxies for which spectra have been obtained so far. Interestingly, it was discovered because of the light emitted by its massive stars and not, as originally expected, from emission by hydrogen gas. PR Photo 13a/03 : Emission from the Earth's atmosphere. PR Photo 13b/03 : CHFT images of the very remote galaxy z6VDF J022803-041618. PR Photo 13c/03 : VLT spectrum of very remote galaxy z6VDF J022803-041618. PR Photo 13d/03 : Cleaned tracing of the VLT spectrum. A brief history of the early Universe Most scientists agree that the Universe emanated from a hot and extremely dense initial state in a Big Bang . The latest observations indicate that this crucial event took place about 13,700 million years ago . During the first few minutes, enormous quantities of hydrogen and helium nuclei with protons and neutrons were produced. There were also lots of free electrons and during the following epoch, the numerous photons were scattered from these and the atomic nuclei. At this stage, the Universe was completely opaque. After some 100,000 years, the Universe had cooled down to a few thousand degrees and the nuclei and electrons now combined to form atoms. The photons were then no longer scattered from these and the Universe suddenly became transparent . Cosmologists refer to this moment as the "recombination epoch" . The microwave background radiation we now observe from all directions depicts the state of great uniformity in the Universe at that distant epoch. In the next phase, the primeval atoms - more than 99% of which were of hydrogen and helium - moved together and began to form huge clouds from which stars and galaxies later emerged . The first generation of stars and, somewhat later, the first galaxies and quasars [4], produced intensive ultraviolet radiation. That radiation did not travel very far, however, despite the fact that the Universe had become transparent a long time ago. This is because the ultraviolet (short-wavelength) photons would be immediately absorbed by the hydrogen atoms, "knocking" electrons off those atoms, while longer-wavelength photons could travel much farther. The intergalactic gas thus again became ionized in steadily growing spheres around the ionizing sources. At some moment, these spheres had become so big that they overlapped completely; this is referred to as the "epoch of re-ionization" . Until then, the ultraviolet radiation was absorbed by the atoms, but the Universe now also became transparent to this radiation. Before, the ultraviolet light from those first stars and galaxies could not be seen over large distances, but now the Universe suddenly appeared to be full of bright objects. It is for this reason that the time interval between the epochs of "recombination" and "re-ionization" is referred to as the "Dark Ages" . When was the end of the "Dark Ages"? The exact epoch of re-ionization is a subject of active debate among astronomers, but recent results from ground and space observations indicate that the "Dark Ages" lasted a few hundred million years . Various research programmes are now underway which attempt to determine better when these early events happened. For this, it is necesary to find and study in detail the earliest and hence, most distant, objects in the Universe - and this is a very demanding observational endeavour. Light is dimmed by the square of the distance and the further we look out in space to observe an object - and therefore the further back in time we see it - the fainter it appears. At the same time, its dim light is shifted towards the red region of the spectrum due to the expansion of the Universe - the larger the distance, the larger the observed redshift [3]. The Lyman-alpha emission line With ground-based telescopes, the faintest detection limits are achieved by observations in the visible part of the spectrum. The detection of very distant objects therefore requires observations of ultraviolet spectral signatures which have been redshifted into the visible region. Normally, the astronomers use for this the redshifted Lyman-alpha spectral emission line with rest wavelength 121.6 nm; it corresponds to photons emitted by hydrogen atoms when they change from an excited state to their fundamental state. One obvious way of searching for the most distant galaxies is therefore to search for Lyman-alpha emission at the reddest (longest) possible wavelengths . The longer the wavelength of the observed Lyman-alpha line, the larger is the redshift and the distance, and the earlier is the epoch at which we see the galaxy and the closer we come towards the moment that marked the end of the "Dark Ages". CCD-detectors used in astronomical instruments (as well as in commercial digital cameras) are sensitive to light of wavelengths up to about 1000 nm (1 µm), i.e., in the very near-infrared spectral region, beyond the reddest light that can be perceived by the human eye at about 700-750 nm. The bright near-infrared night sky ESO PR Photo 13a/03 ESO PR Photo 13a/03 [Preview - JPEG: 759 x 400 pix - 37k [Normal - JPEG: 1518 x 800 pix - 248k] Caption : PR Photo 13a/03 shows a spectrum of emission by the terrestrial atmosphere. In the spectral region above 700 nm, this emission is dominated by strong lines from the OH molecule. By observing in "windows" of low OH emission, such as those around 820 or 920 nm, the "noise" caused by the OH-emission is strongly reduced and it is possible to detect fainter celestial objects. There is another problem, however, for this kind of work. The search for faint Lyman-alpha emission from distant galaxies is complicated by the fact that the terrestrial atmosphere - through which all ground-based telescopes must look - also emits light . This is particularly so in the red and near-infrared part of the spectrum where hundreds of discrete emission lines originate from the hydroxyl molecule (the OH radical) that is present in the upper terrestrial atmosphere at an altitude of about 80 km (see PR Photo 13a/03 ). This strong emission which the astronomers refer to as the "sky background" is responsible for the faintness limit at which celestial objects can be detected with ground-based telescopes at near-infrared wavelengths. However, there are fortunately spectral intervals of "low OH-background" where these emission lines are much fainter, thus allowing a fainter detection limit from ground observations. Two such "dark-sky windows" are evident in PR Photo 13a/03 near wavelengths of 820 and 920 nm. Considering these aspects, a promising way to search efficiently for the most distant galaxies is therefore to observe at wavelengths near 920 nm by means of a narrow-band optical filter. Adapting the spectral width of this filter to about 10 nm allows the detection of as much light from the celestial objects as possible when emitted in a spectral line matching the filter, while minimizing the adverse influence of the sky emission. In other words, with a maximum of light collected from the distant objects and a minimum of disturbing light from the terrestrial atmosphere, the chances for detecting those distant objects are optimal. The astronomers talk about "maximizing the contrast" of objects showing emission lines at this wavelength. The CFHT Search Programme ESO PR Photo 13b/03 ESO PR Photo 13b/03 [Preview - JPEG: 494 x 400 pix - 83k [Normal - JPEG: 987 x 800 pix - 920k] Caption : PR Photo 13b/03 displays the image of a particular object (at the center), as seen at various wavelengths (colours) on CCD-frames obtained through different optical filters with the CFH12K camera at the CFHT. The object is only visible in the NB920 frame in which emission at the near-infrared wavelength 920 nm is registered (upper left). It is not seen in any of the others ( B lue [450 nm], V isual [550 nm], R ed [650 nm], I [800 nm]), nor in a combination of these (the "sum" of BVRI , the so-called "detection" image, here labeled as "Det"; it is used to detect closer objects from their optical colours for spectroscopic follow-up observations). The indicated object was later shown to be an extremely distant galaxy and has been designated z6VDF J022803-041618 . Each of the six photos covers 20 x 20 arcsec 2 ; North is up, East is right. Based on the above considerations, an international team of astronomers [2] installed a narrow-band optical filter centered at the near-infrared wavelength 920 nm on the CFH12K instrument at the Canada-France-Hawaii telescope on Mauna Kea (Hawaii, USA) to search for extremely distant galaxies. The CFH12K is a wide-field camera used at the prime focus of the CFHT, providing a field-of-view of approx. 30 x 40 arcmin 2 , somewhat larger than the full moon [5]. By comparing images of the same sky field taken through different filters, the astronomers were able to identify objects which appear comparatively "bright" in the NB920 image and "faint" (or are even not visible) in the corresponding images obtained through the other filters. A striking example is shown in PR Photo 13b/03 - the object at the center is well visible in the 920nm image, but not at all in the other images. The most probable explanation for an object with such an unusual colour is that it is a very distant galaxy for which the observed wavelength of the strong Lyman-alpha emission line is close to 920 nm, due to the redshift. Any light emitted by the galaxy at wavelengths shorter than Lyman-alpha is strongly absorbed by intervening interstellar and intergalactic hydrogen gas; this is the reason that the object is not visible in all the other filters. The VLT spectrum ESO PR Photo 13c/03 ESO PR Photo 13c/03 [Preview - JPEG: 756 x 300 pix - 68k [Normal - JPEG: 1512 x 600 pix - 552k] ESO PR Photo 13d/03 ESO PR Photo 13d/03 [Preview - JPEG: 479 x 400 pix - 41k [Normal - JPEG: 957 x 800 pix - 272k] Captions : PR Photo 13c/03 shows a spectroscopic image (between the horizontal arrows) of the very distant galaxy z6VDF J022803-041618 at the center of PR Photo 13b/03 , obtained with the multi-mode FORS2 instrument at the 8.2-m VLT YEPUN telescope at the ESO Paranal Observatory. The horizontal axis shows the dispersed light, with wavelengths increasing from left to right. In this spectral image, the bright emission lines from OH molecules in the terrestrial atmosphere, cf. PR Photo 13a/03 , have been subtracted, but they still leave residual "imprints", visible as strong and "noisy" vertical bars. The "window" at wavelength 920 nm is clearly visible on the right side of the image; in this region, there is much less "noise" from the OH-lines. The dark spot at the bottom left of the image is the Lyman-alpha line of the object. The adjacent "continuum" emission from the object, although very faint, is clearly visible on the long-wavelength side (to the right) of the Lyman-alpha line. There is no such continuum emission detected on the short-wavelength side (to the left) of the Lyman alpha line. Together with the observed asymmetry of the line, this is a clear spectral fingerprint of the redshifted Lyman-alpha emission line from a distant galaxy. PR Photo 13d/03 shows a tracing of the spectrum of this galaxy, as extracted from the image in PR Photo 13c/03 . The strong emission line at wavelength 872 nm is the redshifted Lyman-alpha spectral line from the galaxy; it is shown in more detail in the insert panel. In order to learn the true nature of this object, it is necessary to perform a spectroscopic follow-up, by observing its spectrum. This was accomplished with the FORS 2 multi-mode instrument at the 8.2-m VLT YEPUN telescope at the ESO Paranal Observatory. This facility provides a perfect combination of moderate spectral resolution and high sensitivity in the red for this kind of very demanding observation. The resulting (faint) spectrum is shown in PR Photo 13c/03 . PR Photo 13d/03 shows a tracing of the final ("cleaned") spectrum of the object after extraction from the image shown in PR Photo 13c/03 . One broad emission line is clearly detected (to the left of the center; enlarged in the insert). It is asymmetric, being depressed on its blue (left) side. This, combined with the fact that no continuum light is detected to the left of the line, is a clear spectral signature of the Lyman-alpha line: photons "bluer" than Lyman-alpha are heavily absorbed by the gas present in the galaxy itself, and in the intergalactic medium along the line-of-sight between the Earth and the object. The spectroscopic observations therefore allowed the astronomers to identify unambiguously this line as Lyman-alpha, and therefore to confirm the great distance (high redshift) of this particular object. The measured redshift is 6.17, making this object one of the most distant galaxies ever detected . It received the designation "z6VDF J022803-041618" - the first part of this somewhat unwieldy name refers to the survey and the second indicates the position of this galaxy in the sky. Starlight in the early Universe However, these observations did not come without surprise! The astronomers had hoped (and expected) to detect the Lyman-alpha line from the object at the center of the 920 nm spectral window. However, while the Lyman-alpha line was found, it was positioned at a somewhat shorter wavelength. Thus, it was not the Lyman-alpha emission that caused this galaxy to be "bright" in the narrow-band (NB920) image, but "continuum" emission at wavelengths longer than that of Lyman-alpha . This radiation is very faintly visible as a horizontal, diffuse line in PR Photo 13c/03 . One consequence is that the measured redshift of 6.17 is lower than the originally predicted redshift of about 6.5. Another is that z6VDF J022803-041618 was detected by light from its massive stars (the "continuum") and not by emission from hydrogen gas (the Lyman-alpha line). This interesting conclusion is of particular interest as it shows that it is in principle possible to detect galaxies at this enormous distance without having to rely on the Lyman-alpha emission line, which may not always be present in the spectra of the distant galaxies. This will provide the astronomers with a more complete picture of the galaxy population in the early Universe. Moreover, observing more and more of these distant galaxies will help to better understand the ionization state of the Universe at this age: the ultraviolet light emitted by these galaxies should not reach us in a "neutral" Universe, i.e., before re-ionization occurred. The hunt for more such galaxies is now on to clarify how the transition from the Dark Ages happened!

Contributions of different bias-correction methods and reference meteorological forcing data sets to uncertainty in projected temperature and precipitation extremes

NASA Astrophysics Data System (ADS)

Iizumi, Toshichika; Takikawa, Hiroki; Hirabayashi, Yukiko; Hanasaki, Naota; Nishimori, Motoki

2017-08-01

The use of different bias-correction methods and global retrospective meteorological forcing data sets as the reference climatology in the bias correction of general circulation model (GCM) daily data is a known source of uncertainty in projected climate extremes and their impacts. Despite their importance, limited attention has been given to these uncertainty sources. We compare 27 projected temperature and precipitation indices over 22 regions of the world (including the global land area) in the near (2021-2060) and distant future (2061-2100), calculated using four Representative Concentration Pathways (RCPs), five GCMs, two bias-correction methods, and three reference forcing data sets. To widen the variety of forcing data sets, we developed a new forcing data set, S14FD, and incorporated it into this study. The results show that S14FD is more accurate than other forcing data sets in representing the observed temperature and precipitation extremes in recent decades (1961-2000 and 1979-2008). The use of different bias-correction methods and forcing data sets contributes more to the total uncertainty in the projected precipitation index values in both the near and distant future than the use of different GCMs and RCPs. However, GCM appears to be the most dominant uncertainty source for projected temperature index values in the near future, and RCP is the most dominant source in the distant future. Our findings encourage climate risk assessments, especially those related to precipitation extremes, to employ multiple bias-correction methods and forcing data sets in addition to using different GCMs and RCPs.

ROSAT - A German X-ray satellite searches for the big bang

NASA Astrophysics Data System (ADS)

The scientific aims, design, development history, launch, and initial performance of the NASA/FRG orbiting X-ray observatory Rosat are reviewed and illustrated with extensive drawings, diagrams, photographs, and sample images. The main Rosat instrument is a 120-cm-long 83-cm-aperture Wolter X-ray telescope with optical surfaces ground to achieve mean microroughness of less than 1 nm and image resolution 2.5 arcsec. The Rosat mission began with a Delta II launch on June 1, 1990; its first objective is an all-sky X-ray survey which should increase the number of known X-ray sources from about 5000 to over 100,000. The second phase involves detailed observations of selected objects, including nearby normal stars, SN clouds, binary systems, hot neutron stars, and extremely distant QSOs. The first images obtained by Rosat were of the Galactic SNR Cas A, revealing the structure of the shock front and a weak X-ray halo.

KSC-08pd2451

NASA Image and Video Library

2008-08-16

CAPE CANAVERAL, Fla. – Technicians in the Payload Hazardous Servicing Facility complete removal of the protective cover from the Wide Field Camera 3, or WFC3. The WFC3 is part of the payload on space shuttle Atlantis for the fifth and final Hubble servicing mission, STS-125. As Hubble enters the last stage of its life, WFC3 will be Hubble's next evolutionary step, allowing Hubble to peer ever further into the mysteries of the cosmos. WFC3 will study a diverse range of objects and phenomena, from young and extremely distant galaxies, to much more nearby stellar systems, to objects within our very own solar system. WFC3 will take the place of Wide Field Planetary Camera 2, which astronauts will bring back to Earth aboard the shuttle. Launch of Atlantis is targeted at 1:34 a.m. EDT Oct. 8. Photo credit: NASA/Jack Pfaller

KSC-08pd2393

NASA Image and Video Library

2008-08-12

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, an overhead crane is moved above the Wide Field Camera 3, or WFC3, for attachment. The WFC3 will be lifted and transferred to a work stand. As Hubble enters the last stage of its life, WFC3 will be Hubble's next evolutionary step, allowing Hubble to peer ever further into the mysteries of the cosmos. WFC3 will study a diverse range of objects and phenomena, from young and extremely distant galaxies, to much more nearby stellar systems, to objects within our very own solar system. WFC3 will take the place of Wide Field Planetary Camera 2, which astronauts will bring back to Earth aboard the shuttle. WFC3 is part of the payload on the fifth and final Hubble servicing mission, STS-125, targeted for launch Oct. 8. Photo credit: NASA/Jack Pfaller

KSC-08pd2453

NASA Image and Video Library

2008-08-18

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, technicians check the Wide Field Camera 3, or WFC3, after removal of its protective cover. WFC3 is part of the payload on space shuttle Atlantis' STS-125 mission for the fifth and final Hubble servicing flight to NASA's Hubble Space Telescope. As Hubble enters the last stage of its life, WFC3 will be Hubble's next evolutionary step, allowing Hubble to peer ever further into the mysteries of the cosmos. WFC3 will study a diverse range of objects and phenomena, from young and extremely distant galaxies, to much more nearby stellar systems, to objects within our very own solar system. WFC3 will take the place of Wide Field Planetary Camera 2, which astronauts will bring back to Earth aboard the shuttle. Launch of Atlantis is targeted at 1:34 a.m. EDT Oct. 8. Photo credit: NASA/Amanda Diller

KSC-08pd2454

NASA Image and Video Library

2008-08-18

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, technicians check the Wide Field Camera 3, or WFC3, after removal of its protective cover. WFC3 is part of the payload on space shuttle Atlantis' STS-125 mission for the fifth and final Hubble servicing flight to NASA's Hubble Space Telescope. As Hubble enters the last stage of its life, WFC3 will be Hubble's next evolutionary step, allowing Hubble to peer ever further into the mysteries of the cosmos. WFC3 will study a diverse range of objects and phenomena, from young and extremely distant galaxies, to much more nearby stellar systems, to objects within our very own solar system. WFC3 will take the place of Wide Field Planetary Camera 2, which astronauts will bring back to Earth aboard the shuttle. Launch of Atlantis is targeted at 1:34 a.m. EDT Oct. 8. Photo credit: NASA/Amanda Diller

KSC-08pd2474

NASA Image and Video Library

2008-08-18

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, the Wide Field Camera 3, or WFC3, is lowered onto the Super Lightweight Interchangeable Carrier. WFC3 is part of the payload on space shuttle Atlantis' STS-125 mission for the fifth and final Hubble servicing flight to NASA's Hubble Space Telescope. As Hubble enters the last stage of its life, WFC3 will be Hubble's next evolutionary step, allowing Hubble to peer ever further into the mysteries of the cosmos. WFC3 will study a diverse range of objects and phenomena, from young and extremely distant galaxies, to much more nearby stellar systems, to objects within our very own solar system. WFC3 will take the place of Wide Field Planetary Camera 2, which astronauts will bring back to Earth aboard the shuttle. Launch of Atlantis is targeted at 1:34 a.m. EDT Oct. 8. Photo credit: NASA/Amanda Diller

KSC-08pd2472

NASA Image and Video Library

2008-08-18

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, the Wide Field Camera 3, or WFC3, is moved toward the Super Lightweight Interchangeable Carrier. WFC3 is part of the payload on space shuttle Atlantis' STS-125 mission for the fifth and final Hubble servicing flight to NASA's Hubble Space Telescope. As Hubble enters the last stage of its life, WFC3 will be Hubble's next evolutionary step, allowing Hubble to peer ever further into the mysteries of the cosmos. WFC3 will study a diverse range of objects and phenomena, from young and extremely distant galaxies, to much more nearby stellar systems, to objects within our very own solar system. WFC3 will take the place of Wide Field Planetary Camera 2, which astronauts will bring back to Earth aboard the shuttle. Launch of Atlantis is targeted at 1:34 a.m. EDT Oct. 8. Photo credit: NASA/Amanda Diller

KSC-08pd2473

NASA Image and Video Library

2008-08-18

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, the Wide Field Camera 3, or WFC3, is lowered toward the Super Lightweight Interchangeable Carrier. WFC3 is part of the payload on space shuttle Atlantis' STS-125 mission for the fifth and final Hubble servicing flight to NASA's Hubble Space Telescope. As Hubble enters the last stage of its life, WFC3 will be Hubble's next evolutionary step, allowing Hubble to peer ever further into the mysteries of the cosmos. WFC3 will study a diverse range of objects and phenomena, from young and extremely distant galaxies, to much more nearby stellar systems, to objects within our very own solar system. WFC3 will take the place of Wide Field Planetary Camera 2, which astronauts will bring back to Earth aboard the shuttle. Launch of Atlantis is targeted at 1:34 a.m. EDT Oct. 8. Photo credit: NASA/Amanda Diller

KSC-08pd2471

NASA Image and Video Library

2008-08-18

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, an overhead crane lifts the Wide Field Camera 3, or WFC3, above the stand holding the Super Lightweight Interchangeable Carrier. WFC3 is part of the payload on space shuttle Atlantis' STS-125 mission for the fifth and final Hubble servicing flight to NASA's Hubble Space Telescope. As Hubble enters the last stage of its life, WFC3 will be Hubble's next evolutionary step, allowing Hubble to peer ever further into the mysteries of the cosmos. WFC3 will study a diverse range of objects and phenomena, from young and extremely distant galaxies, to much more nearby stellar systems, to objects within our very own solar system. WFC3 will take the place of Wide Field Planetary Camera 2, which astronauts will bring back to Earth aboard the shuttle. Launch of Atlantis is targeted at 1:34 a.m. EDT Oct. 8. Photo credit: NASA/Amanda Diller

KSC-08pd2458

NASA Image and Video Library

2008-08-18

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, the Wide Field Camera 3, or WFC3, is ready to be transferred to the Super Lightweight Interchangeable Carrier. WFC3 is part of the payload on space shuttle Atlantis' STS-125 mission for the fifth and final Hubble servicing flight to NASA's Hubble Space Telescope. As Hubble enters the last stage of its life, WFC3 will be Hubble's next evolutionary step, allowing Hubble to peer ever further into the mysteries of the cosmos. WFC3 will study a diverse range of objects and phenomena, from young and extremely distant galaxies, to much more nearby stellar systems, to objects within our very own solar system. WFC3 will take the place of Wide Field Planetary Camera 2, which astronauts will bring back to Earth aboard the shuttle. Launch of Atlantis is targeted at 1:34 a.m. EDT Oct. 8. Photo credit: NASA/Amanda Diller

KSC-08pd2448

NASA Image and Video Library

2008-08-16

CAPE CANAVERAL, Fla. – The Wide Field Camera 3, or WFC3, rests on a work stand in the Payload Hazardous Servicing Facility since its arrival Aug. 12. WFC3 is part of the payload on space shuttle Atlantis for the fifth and final Hubble servicing mission, STS-125. As Hubble enters the last stage of its life, WFC3 will be Hubble's next evolutionary step, allowing Hubble to peer ever further into the mysteries of the cosmos. WFC3 will study a diverse range of objects and phenomena, from young and extremely distant galaxies, to much more nearby stellar systems, to objects within our very own solar system. WFC3 will take the place of Wide Field Planetary Camera 2, which astronauts will bring back to Earth aboard the shuttle. Launch of Atlantis is targeted at 1:34 a.m. EDT Oct. 8. Photo credit: NASA/Jack Pfaller

KSC-08pd2394

NASA Image and Video Library

2008-08-12

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, an overhead crane begins to lift the Wide Field Camera 3, or WFC3, from the base of the shipping container. The WFC3 will be transferred to a work stand. As Hubble enters the last stage of its life, WFC3 will be Hubble's next evolutionary step, allowing Hubble to peer ever further into the mysteries of the cosmos. WFC3 will study a diverse range of objects and phenomena, from young and extremely distant galaxies, to much more nearby stellar systems, to objects within our very own solar system. WFC3 will take the place of Wide Field Planetary Camera 2, which astronauts will bring back to Earth aboard the shuttle. WFC3 is part of the payload on the fifth and final Hubble servicing mission, STS-125, targeted for launch Oct. 8. Photo credit: NASA/Jack Pfaller

KSC-08pd2395

NASA Image and Video Library

2008-08-12

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, an overhead crane lifts the Wide Field Camera 3, or WFC3, from the base of the shipping container. The WFC3 will be transferred to a work stand. As Hubble enters the last stage of its life, WFC3 will be Hubble's next evolutionary step, allowing Hubble to peer ever further into the mysteries of the cosmos. WFC3 will study a diverse range of objects and phenomena, from young and extremely distant galaxies, to much more nearby stellar systems, to objects within our very own solar system. WFC3 will take the place of Wide Field Planetary Camera 2, which astronauts will bring back to Earth aboard the shuttle. WFC3 is part of the payload on the fifth and final Hubble servicing mission, STS-125, targeted for launch Oct. 8. Photo credit: NASA/Jack Pfaller

KSC-08pd2452

NASA Image and Video Library

2008-08-16

CAPE CANAVERAL, Fla. – Technicians in the Payload Hazardous Servicing Facility complete removal of the protective cover from the Wide Field Camera 3, or WFC3. The WFC3 is part of the payload on space shuttle Atlantis for the fifth and final Hubble servicing mission, STS-125. As Hubble enters the last stage of its life, WFC3 will be Hubble's next evolutionary step, allowing Hubble to peer ever further into the mysteries of the cosmos. WFC3 will study a diverse range of objects and phenomena, from young and extremely distant galaxies, to much more nearby stellar systems, to objects within our very own solar system. WFC3 will take the place of Wide Field Planetary Camera 2, which astronauts will bring back to Earth aboard the shuttle. Launch of Atlantis is targeted at 1:34 a.m. EDT Oct. 8. Photo credit: NASA/Jack Pfaller

WISE Discovery of Hyper Luminous Galaxies at z=2-4 and Their Implications for Galaxy and AGN Evolution

NASA Technical Reports Server (NTRS)

Tsai, Chao Wei; Eisenhardt, Peter; Wu, Jingwen; Bridge, Carrie; Assef, Roberto; Benford, Dominic; Blain, Andrew; Cutri, Roc; Griffith, Robert L.; Jarrett, Thomas;

Eat Me If You Can: Cognitive Mechanisms Underlying the Distance Effect

PubMed Central

Junghans, Astrid F.; Evers, Catharine; De Ridder, Denise T. D.

2013-01-01

Proximal objects provide affordances that activate the motor information involved in interacting with the objects. This effect has previously been shown for artifacts but not for natural objects, such as food. This study examined whether the sight of proximal food, compared to distant food activates eating-related information. In two experiments reaction times to verbal labels following the sight of proximal and distant objects (food and toys) were measured. Verbal labels included function words that were compatible with one object category (eating and playing) and observation words compatible with both object categories. The sight of food was expected to activate eating-related information when presented at proximity but not at distance, as reflected by faster reaction times to proximal than distant compatible eating words and no difference between reaction times to proximal and distant food for observation words (Experiment 1). Experiment 2 additionally compared the reaction times to wrapped and unwrapped food. The distance effect was expected to occur only for unwrapped food because only unwrapped food is readily edible. As expected, Experiment 1 and 2 revealed faster responses to compatible eating words at proximity than at distance. In Experiment 2 this distance effect occurred only for readily edible, unwrapped food but not for wrapped food. For observation words no difference in response times between the distances was found. These findings suggest that the sight of proximal food activates eating-related information, which could explain people’s differential behavioral responses to reachable versus distant food. The activation of eating-related information upon sight of accessible food could provide a cognition-based explanation for mindless eating. PMID:24367684

The Living Cosmos

NASA Astrophysics Data System (ADS)

Impey, Chris

2011-06-01

Preface; 1. The unfinished revolution; 2. Life's origins; 3. Extreme life; 4. Shaping evolution; 5. Living in the Solar System; 6. Distant worlds; 7. Are we alone?; Notes; Glossary; Reading list; Media resources; Illustration credits; Index.

Cosmic flashing lights

NASA Astrophysics Data System (ADS)

Di Stefano, Rosanne

2018-04-01

Gravitational lensing is becoming increasingly important to the study of distant galaxies and dark matter. Two groups have recently detected transient events emanating from far-away lensed galaxies, apparently due to extreme magnification of individual stars.

HUBBLE OPENS ITS EYE ON THE UNIVERSE AND CAPTURES A COSMIC MAGNIFYING GLASS

NASA Technical Reports Server (NTRS)

2002-01-01

Scanning the heavens for the first time since the successful December 1999 servicing mission, NASA's Hubble Space Telescope has imaged a giant, cosmic magnifying glass, a massive cluster of galaxies called Abell 2218. This 'hefty' cluster resides in the constellation Draco, some 2 billion light-years from Earth. The cluster is so massive that its enormous gravitational field deflects light rays passing through it, much as an optical lens bends light to form an image. This phenomenon, called gravitational lensing, magnifies, brightens, and distorts images from faraway objects. The cluster's magnifying powers provides a powerful 'zoom lens' for viewing distant galaxies that could not normally be observed with the largest telescopes. This useful phenomenon has produced the arc-shaped patterns found throughout the Hubble picture. These 'arcs' are the distorted images of very distant galaxies, which lie 5 to 10 times farther than the lensing cluster. This distant population existed when the universe was just a quarter of its present age. Through gravitational lensing these remote objects are magnified, enabling scientists to study them in more detail. This analysis provides a direct glimpse of how star-forming regions are distributed in remote galaxies and yields other clues to the early evolution of galaxies. The picture is dominated by spiral and elliptical galaxies. Resembling a string of tree lights, the biggest and brightest galaxies are members of the foreground cluster. Researchers are intrigued by a tiny red dot just left of top center. This dot may be an extremely remote object made visible by the cluster's magnifying powers. Further investigation is needed to confirm the object's identity. The Hubble telescope first viewed this cluster in 1994, producing one of the most spectacular demonstrations of gravitational lensing up to that time. Scientists who analyzed that black-and-white picture discovered more than 50 remote, young galaxies. Hubble's latest multicolor image of the cluster will allow astronomers to probe in greater detail the internal structure of these early galaxies. The color picture already reveals several arc-shaped features that are embedded in the cluster and cannot be easily seen in the black-and-white image. The colors in this picture yield clues to the ages, distances, and temperatures of stars, the stuff of galaxies. Blue pinpoints hot young stars. The yellow-white color of several of the galaxies represents the combined light of many stars. Red identifies cool stars, old stars, and the glow of stars in distant galaxies. This view is only possible by combining Hubble's unique image quality with the rare lensing effect provided by the magnifying cluster. The picture was taken Jan. 11 to 13, 2000, with the Wide Field and Planetary Camera 2. Credits: NASA, Andrew Fruchter (STScI), and the ERO team (STScI, ST-ECF)

Discovery, Orbit and Orbital Evolution of the Distant Object (463368) 2012 VU85

NASA Astrophysics Data System (ADS)

Wlodarczyk, I.; Černis, K.; Boyle, R. P.

2017-03-01

We present the discovery and time evolution of orbital elements of the distant Centaur-type object (463368) 2012 VU85. From all 2135 distant objects listed in the Minor Planet Center we select all 347 numbered distant object and integrate their equations of motion in the 1 Gyr forward and backward integration. The asteroid (463368) 2012 VU85 lies on the border of the group of 347 distant objects, which have a semimajor axis about 44 a.u., eccentricity 0.1 and inclination between 0° and 30°. We show that after 1 Gyr of forward integration, about half of the objects are expelled from the Solar System, \\ie their median lifetime is about 1 Gyr. We note that the long-lived distant objects are mainly located between the regions where Neptune controls aphelia of asteroids and the asteroids are in the mean motion resonance 2/3 with Neptune. We find eight almost regular approaches of clones of the asteroid (463368) 2012 VU85 to Neptune and several generally shorter in time regular approaches to Uranus. For other outer planets we did not detect any approaches below 5 a.u. for a period of 15 000 yr in forward and backward integrations. In our calculations we find eight episodes, each lasting about 3000 yr when the value of inclination oscillates around its average. These changes look similar to the changes of semimajor axis during the occurrence of orbital mean motion resonance with a planet. We find that half of the clones of the asteroid (463368) 2012 VU85 remain in the Solar System for a forward integration of 44 Myr, and for a backward integration of 34 Myr. This is a significantly shorter escape time as compared to the group of distant objects. Almost all long-lived clones have value of Tisserand parameter with respect to Neptune smaller than 3 during the whole 1 Gyr forward and backward integrations. This implies that there are several clones of the asteroid (463368) 2012 VU85 that cross the orbits of Neptune and Uranus. We find many orbital mean motion resonances lasting up to several Myr in the motion of the asteroid (463368) 2012 VU85. According to our computations the presence of the Kozai resonance protects the asteroid from the close approaches with Uranus and Neptune. The Lyapunov time for the asteroid (463368) 2012 VU85 is equal to 4260 years.

Same Old Story: The Problem of Object-Based Thinking as a Basis for Teaching Distant Places

ERIC Educational Resources Information Center

Martin, Fran

2013-01-01

The English Geography National Curriculum encourages primary teachers to focus on similarities and differences when teaching distant places. The issues this raises are particularly acute when teaching geography in the context of the Global South. In this article I argue that comparisons based on object-based thinking can lead to views of the…

KENNEDY SPACE CENTER, FLA. - Workers calibrate a tracking telescope, part of the Distant Object Attitude Measurement System (DOAMS), located in Cocoa Beach, Fla. The telescope provides optical support for launches from KSC and Cape Canaveral.

NASA Image and Video Library

2003-09-03

KENNEDY SPACE CENTER, FLA. - Workers calibrate a tracking telescope, part of the Distant Object Attitude Measurement System (DOAMS), located in Cocoa Beach, Fla. The telescope provides optical support for launches from KSC and Cape Canaveral.

Metacognitive inferences from other people's memory performance.

PubMed

Smith, Robert W; Schwarz, Norbert

2016-09-01

Three studies show that people draw metacognitive inferences about events from how well others remember the event. Given that memory fades over time, detailed accounts of distant events suggest that the event must have been particularly memorable, for example, because it was extreme. Accordingly, participants inferred that a physical assault (Study 1) or a poor restaurant experience (Studies 2-3) were more extreme when they were well remembered one year rather than one week later. These inferences influence behavioral intentions. For example, participants recommended a more severe punishment for a well-remembered distant rather than recent assault (Study 1). These metacognitive inferences are eliminated when people attribute the reporter's good memory to an irrelevant cause (e.g., photographic memory), thus undermining the informational value of memory performance (Study 3). These studies illuminate how people use lay theories of memory to learn from others' memory performance about characteristics of the world. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

The nature of radio emission from distant galaxies

NASA Astrophysics Data System (ADS)

Richards, Eric A.

I describe an observational program aimed at understanding the radio emission from distant, rapidly evolving galaxy populations. These observations were carried out at 1.4 and 8.5 GHz with the VLA centered on the Hubble Deep Field. Further MERLIN observations of the HDF region at 1.4 GHz provided an angular resolution of 0.2'' and when combined with the VLA data produced an image with an unprecedented rms noise of 4 μJy. All radio sources detected in the VLA complete sample are resolved with a median angular size of 1-2''. The differential count of the radio sources is marginally sub-Euclidean (γ = -2.4 +/- 0.1) and fluctuation analysis suggests nearly 60 sources per armin2 are present at the 1 μJy level. A correlation analysis indicates spatial clustering among the 371 radio sources on angular scales of 1-40 arcmin. Optical identifications are made primarily with bright (I = 22) disk systems composed of irregulars, peculiars, interacting/merging galaxies, and a few isolated field spirals. Available redshifts span the range 0.2-3. These clues coupled with the steep spectral index of the 1.4 GHz selected sample are indicative of diffuse synchrotron radiation in distant galactic disks. Thus the evolution in the microjansky radio population is driven principally by star-formation. I have isolated a number of optically faint radio sources (about 25% of the overall sample) which remain unidentified to I = 26-28 in the HDF and flanking optical fields. Several of these objects have extremely red counterparts and constitute a new class of radio sources which are candidate high redshift dusty protogalaxies.

KENNEDY SPACE CENTER, FLA. - A worker calibrates a tracking telescope, part of the Distant Object Attitude Measurement System (DOAMS), located in Cocoa Beach, Fla. The telescope provides optical support for launches from KSC and Cape Canaveral.

NASA Image and Video Library

2003-09-03

KENNEDY SPACE CENTER, FLA. - A worker calibrates a tracking telescope, part of the Distant Object Attitude Measurement System (DOAMS), located in Cocoa Beach, Fla. The telescope provides optical support for launches from KSC and Cape Canaveral.

Some aspects of the cosmogonic outward migration of Neptune. Co-planar migration

NASA Astrophysics Data System (ADS)

Neslušan, L.; Jakubík, M.

2013-10-01

Considering a simple model of the cosmogonic outward migration of Neptune, we investigate if the assumption of an extremely low orbital inclination of small bodies in a once-existing proto-planetary disk could influence the structure of reservoirs of the objects in the trans-Neptunian region. We found no significant influence. Our models predict only the existence of the mean-motion resonances (MMRs) with Neptune 2:3, 3:5, 1:2, and an anemic scattered disk (MMRs 3:4, 5:7, and 9:11 are also indicated). To explain the classical Edgeworth-Kuiper belt, relatively abundant 4:7 and 2:5 MMRs, and the more numerous scattered disk, we need to assume that, e.g., the outer boundary of the original proto-planetary disk considerably exceeded the distance of the current Neptune's orbit (Neptune probably ended its migration at the distance, where the disk's density started to be sub-critical), or that some Pluto-sized objects resided inside the MMRs and in the distant parts of the original proto-planetary disk.

KSC-08pd2470

NASA Image and Video Library

2008-08-18

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, an overhead crane lifts the Wide Field Camera 3, or WFC3, high above the floor for transfer to the Super Lightweight Interchangeable Carrier. WFC3 is part of the payload on space shuttle Atlantis' STS-125 mission for the fifth and final Hubble servicing flight to NASA's Hubble Space Telescope. As Hubble enters the last stage of its life, WFC3 will be Hubble's next evolutionary step, allowing Hubble to peer ever further into the mysteries of the cosmos. WFC3 will study a diverse range of objects and phenomena, from young and extremely distant galaxies, to much more nearby stellar systems, to objects within our very own solar system. WFC3 will take the place of Wide Field Planetary Camera 2, which astronauts will bring back to Earth aboard the shuttle. Launch of Atlantis is targeted at 1:34 a.m. EDT Oct. 8. Photo credit: NASA/Amanda Diller

KSC-08pd2457

NASA Image and Video Library

2008-08-18

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, a technician checks the pick-off mirror on the Wide Field Camera 3, or WFC3, that will be installed on NASA's Hubble Space Telescope. WFC3 is part of the payload on space shuttle Atlantis' STS-125 mission for the fifth and final Hubble servicing flight to Hubble. As Hubble enters the last stage of its life, WFC3 will be Hubble's next evolutionary step, allowing Hubble to peer ever further into the mysteries of the cosmos. WFC3 will study a diverse range of objects and phenomena, from young and extremely distant galaxies, to much more nearby stellar systems, to objects within our very own solar system. WFC3 will take the place of Wide Field Planetary Camera 2, which astronauts will bring back to Earth aboard the shuttle. Launch of Atlantis is targeted at 1:34 a.m. EDT Oct. 8. Photo credit: NASA/Amanda Diller

KSC-08pd2459

NASA Image and Video Library

2008-08-18

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, technicians check the placement of an overhead crane to the Wide Field Camera 3, or WFC3, that will transfer the WFC3 to the Super Lightweight Interchangeable Carrier. WFC3 is part of the payload on space shuttle Atlantis' STS-125 mission for the fifth and final Hubble servicing flight to NASA's Hubble Space Telescope. As Hubble enters the last stage of its life, WFC3 will be Hubble's next evolutionary step, allowing Hubble to peer ever further into the mysteries of the cosmos. WFC3 will study a diverse range of objects and phenomena, from young and extremely distant galaxies, to much more nearby stellar systems, to objects within our very own solar system. WFC3 will take the place of Wide Field Planetary Camera 2, which astronauts will bring back to Earth aboard the shuttle. Launch of Atlantis is targeted at 1:34 a.m. EDT Oct. 8. Photo credit: NASA/Amanda Diller

KSC-08pd2469

NASA Image and Video Library

2008-08-18

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, an overhead crane moves the Wide Field Camera 3, or WFC3, from its stand. The WFC3 will be transferred to the Super Lightweight Interchangeable Carrier. WFC3 is part of the payload on space shuttle Atlantis' STS-125 mission for the fifth and final Hubble servicing flight to NASA's Hubble Space Telescope. As Hubble enters the last stage of its life, WFC3 will be Hubble's next evolutionary step, allowing Hubble to peer ever further into the mysteries of the cosmos. WFC3 will study a diverse range of objects and phenomena, from young and extremely distant galaxies, to much more nearby stellar systems, to objects within our very own solar system. WFC3 will take the place of Wide Field Planetary Camera 2, which astronauts will bring back to Earth aboard the shuttle. Launch of Atlantis is targeted at 1:34 a.m. EDT Oct. 8. Photo credit: NASA/Amanda Diller

Space Shuttle Projects

NASA Image and Video Library

1996-11-01

This STS-80 onboard photograph shows the Orbiting Retrievable Far and Extreme Ultraviolet Spectrometer-Shuttle Pallet Satellite II (ORFEUS-SPAS II), photographed during approach by the Space Shuttle Orbiter Columbia for retrieval. Built by the German Space Agency, DARA, the ORFEUS-SPAS II, a free-flying satellite, was dedicated to astronomical observations at very short wavelengths to: investigate the nature of hot stellar atmospheres, investigate the cooling mechanisms of white dwarf stars, determine the nature of accretion disks around collapsed stars, investigate supernova remnants, and investigate the interstellar medium and potential star-forming regions. Some 422 observations of almost 150 astronomical objects were completed, including the Moon, nearby stars, distant Milky Way stars, stars in other galaxies, active galaxies, and quasar 3C273. The STS-80 mission was launched November 19, 1996.

Convergent local adaptation to climate in distantly related conifers.

PubMed

Yeaman, Sam; Hodgins, Kathryn A; Lotterhos, Katie E; Suren, Haktan; Nadeau, Simon; Degner, Jon C; Nurkowski, Kristin A; Smets, Pia; Wang, Tongli; Gray, Laura K; Liepe, Katharina J; Hamann, Andreas; Holliday, Jason A; Whitlock, Michael C; Rieseberg, Loren H; Aitken, Sally N

2016-09-23

When confronted with an adaptive challenge, such as extreme temperature, closely related species frequently evolve similar phenotypes using the same genes. Although such repeated evolution is thought to be less likely in highly polygenic traits and distantly related species, this has not been tested at the genome scale. We performed a population genomic study of convergent local adaptation among two distantly related species, lodgepole pine and interior spruce. We identified a suite of 47 genes, enriched for duplicated genes, with variants associated with spatial variation in temperature or cold hardiness in both species, providing evidence of convergent local adaptation despite 140 million years of separate evolution. These results show that adaptation to climate can be genetically constrained, with certain key genes playing nonredundant roles. Copyright © 2016, American Association for the Advancement of Science.

Multimodality management of soft tissue tumors in the extremity

PubMed Central

Crago, Aimee M.; Lee, Ann Y.

2016-01-01

Most extremity soft tissue sarcomas present as a painless mass. Workup should generally involve cross-sectional imaging with MRI, as well as a core biopsy for pathologic diagnosis. Limb-sparing surgery is the standard of care, and may be supplemented with radiation for histologic subtypes at higher risk for local recurrence and chemotherapy for those at higher risk for distant metastases. This article reviews the work-up and surgical approach to extremity soft tissue sarcomas, as well as the role for radiation and chemotherapy, with particular attention given to the distinguishing characteristics of some of the most common subtypes. PMID:27542637

Distant Galaxy Clusters Hosting Extreme Central Galaxies

NASA Astrophysics Data System (ADS)

McDonald, Michael

2014-09-01

The recently-discovered Phoenix cluster harbors the most star-forming central cluster galaxy of any cluster in the known Universe, by nearly a factor of 10. This extreme system appears to be fulfilling early cooling flow predictions, although the lack of similar systems makes any interpretation difficult. In an attempt to find other "Phoenix-like" clusters, we have cross-correlated archival all-sky surveys (in which Phoenix was detected) and isolated 4 similarly-extreme systems which are also coincident in position and redshift with an overdensity of red galaxies. We propose here to obtain Chandra observations of these extreme, Phoenix-like systems, in order to confirm them as relaxed, rapidly-cooling galaxy clusters.

Discounting the distant future-Data on Australian discount rates estimated by a stochastic interest rate model.

PubMed

Truong, Chi; Trück, Stefan

2017-04-01

Data on certainty equivalent discount factors and discount rates for stochastic interest rates in Australia are provided in this paper. The data has been used for the analysis of investments into climate adaptation projects in ׳It׳s not now or never: Implications of investment timing and risk aversion on climate adaptation to extreme events ׳ (Truong and Trück, 2016) [3] and can be used for other cost-benefit analysis studies in Australia. The data is of particular interest for the discounting of projects that create monetary costs and benefits in the distant future.

Unbound or distant planetary mass population detected by gravitational microlensing.

PubMed

2011-05-19

Since 1995, more than 500 exoplanets have been detected using different techniques, of which 12 were detected with gravitational microlensing. Most of these are gravitationally bound to their host stars. There is some evidence of free-floating planetary-mass objects in young star-forming regions, but these objects are limited to massive objects of 3 to 15 Jupiter masses with large uncertainties in photometric mass estimates and their abundance. Here, we report the discovery of a population of unbound or distant Jupiter-mass objects, which are almost twice (1.8(+1.7)(-0.8)) as common as main-sequence stars, based on two years of gravitational microlensing survey observations towards the Galactic Bulge. These planetary-mass objects have no host stars that can be detected within about ten astronomical units by gravitational microlensing. However, a comparison with constraints from direct imaging suggests that most of these planetary-mass objects are not bound to any host star. An abrupt change in the mass function at about one Jupiter mass favours the idea that their formation process is different from that of stars and brown dwarfs. They may have formed in proto-planetary disks and subsequently scattered into unbound or very distant orbits.

SU-F-R-46: Predicting Distant Failure in Lung SBRT Using Multi-Objective Radiomics Model

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhou, Z; Folkert, M; Iyengar, P

2016-06-15

Purpose: To predict distant failure in lung stereotactic body radiation therapy (SBRT) in early stage non-small cell lung cancer (NSCLC) by using a new multi-objective radiomics model. Methods: Currently, most available radiomics models use the overall accuracy as the objective function. However, due to data imbalance, a single object may not reflect the performance of a predictive model. Therefore, we developed a multi-objective radiomics model which considers both sensitivity and specificity as the objective functions simultaneously. The new model is used to predict distant failure in lung SBRT using 52 patients treated at our institute. Quantitative imaging features of PETmore » and CT as well as clinical parameters are utilized to build the predictive model. Image features include intensity features (9), textural features (12) and geometric features (8). Clinical parameters for each patient include demographic parameters (4), tumor characteristics (8), treatment faction schemes (4) and pretreatment medicines (6). The modelling procedure consists of two steps: extracting features from segmented tumors in PET and CT; and selecting features and training model parameters based on multi-objective. Support Vector Machine (SVM) is used as the predictive model, while a nondominated sorting-based multi-objective evolutionary computation algorithm II (NSGA-II) is used for solving the multi-objective optimization. Results: The accuracy for PET, clinical, CT, PET+clinical, PET+CT, CT+clinical, PET+CT+clinical are 71.15%, 84.62%, 84.62%, 85.54%, 82.69%, 84.62%, 86.54%, respectively. The sensitivities for the above seven combinations are 41.76%, 58.33%, 50.00%, 50.00%, 41.67%, 41.67%, 58.33%, while the specificities are 80.00%, 92.50%, 90.00%, 97.50%, 92.50%, 97.50%, 97.50%. Conclusion: A new multi-objective radiomics model for predicting distant failure in NSCLC treated with SBRT was developed. The experimental results show that the best performance can be obtained by combining all features.« less

Pressure wave injuries to the nervous system caused by high-energy missile extremity impact: Part II. Distant effects on the central nervous system--a light and electron microscopic study on pigs.

PubMed

Suneson, A; Hansson, H A; Seeman, T

1990-03-01

The aim of the present study was to investigate if distant effects could be detected within the central nervous system after impact of a high-energy missile in the left thigh of young pigs. Pressure transducers implanted in various parts of the body of the animal, including the brain, recorded a short-lasting burst of oscillating pressure waves with high frequencies and large amplitudes, traversing the body tissue with a velocity of about that of sound in water (1,460 m/s). The distance between the point of impact and the brain and cervical spinal cord is in the range of 0.5 m. Macroscopic examination revealed that there was no gross brain tissue disruption or visible blood-brain barrier dysfunction. Light microscopic examination demonstrated myelin invaginations in the largest axons and shrinkage of axoplasm. Electron microscopic examination revealed a reduction in the number of microtubules, especially in the larger axons in the brainstem. Disintegration of Nissl substance, i.e., chromatolysis, was noticed after 48 hr in many Purkinje nerve cells in the cerebellum, concomitantly with the appearance of an increased frequency of association between lamellar bodies and mitochondria. Changes could also be observed in the cervical spinal cord and, at reduced frequency and extent, in the optic nerve and in other parts of the brain. These effects were evident within a few minutes after the trauma and persisted even 48 hr after the extremity injury. It is concluded that distant effects, likely to be caused by the oscillating high-frequency pressure waves, appear in the central nervous system after a high-energy missile extremity impact.

[A rare tumor of the parapharyngeal space: myxoid chondrosarcoma].

PubMed

Bahri, I; Boudawara, T; Sellami, A; Khabir, A; Ghorgel, M; Drira, M; Daoud, J; Jlidi, R

2002-01-01

Extrasqueletal myxoid chondrosarcoma (EMC) is an uncommon soft tissue malignant tumor, locally aggressive with a high incidence of distant metastasis. It has distinctive clinical, immunophenotypic, cytogenetic and ultrastructural features. Most EMC are associated with the translocation t(9;22) (q22;q12). Their occurrence in the parapharyngeal space is extremely rare. Our objective is to discuss the difficulties of the histological diagnosis of EMC and to describe its immunophenotypic, cytogenetic features and clinical behavior. We report a case of a 67 years old woman who presented with a five months history of dysphagia. The oral examination found a mass displacing the posterior and left walls of the pharynx. Surgical resection of the tumor was undertaken. The pathologic examination concluded to the diagnosis of an EMC of the left parapharygeal space. Now, the patient is receiving an adjuvant radiotherapy.

Distant and Regional Atmospheric Circulation Influences Governing Integrated Water Vapor Transport and the Occurrence of Extreme Precipitation Events

NASA Astrophysics Data System (ADS)

Bosart, L. F.; Papin, P. P.; Bentley, A. M.

2017-12-01

This presentation will show how the evolution of the large-scale and regional-scale atmospheric circulation contributes to the occurrence of extreme precipitation events (EPEs). An EPE requires that tropospheric moisture flux convergence (MFC) and the associated removal of hydrometeors be balanced by moisture replenishment via integrated (water) vapor transport (IVT) to continuously replenish condensed moisture. Moisture source regions may be distant or regional. Distant moisture sources may require the interaction of lower- and upper-level jet streams with a pre-existing mobile atmospheric disturbance to produce sufficient lift to condense moisture. Pre-existing regional moisture sources may require frontal lifting the presence of MFC to condense moisture. In cases of long-range IVT, such as moisture from a western North Pacific typhoon being drawn poleward along an atmospheric river (AR) toward the west coast of North America, moisture may be transported 1000s of kilometers along a low-level jet before a combination of dynamic and orographic lift results in an EPE. Alternatively, in the case of a typical summer warm and humid air mass over the continental United States, unused moisture may exist for several days in this air mass before sufficient MFC associated with a thermally direct mesoscale frontal circulation can concentrate and condense the moisture. In this case, there may be no long-range IVT via ARs. Instead, the atmospheric circulations may evolve to produce sustained MFC associated with mesoscale frontal circulations, especially in the presence of complex terrain, to produce an EPE. During this presentation, examples of EPEs associated with long-range IVT and distant MFC versus EPEs associated with regional MFC and mesoscale frontal circulations will be illustrated.

Uses for lunar crawler transporters

NASA Astrophysics Data System (ADS)

Kaden, Richard A.

This article discusses state-of-the-art crawler transporters and expresses the need for additional research and development for lunar crawlers. The thrust of the paper illustrates how the basic crawler technology has progressed to a point where extremely large modules can be shop fabricated and move to some distant location at a considerable savings. Also, extremely heavy loads may be lifted by large crawler cranes and placed in designed locations. The Transi-Lift Crawler crane with its traveling counterweight is an attractive concept for lunar construction.

Galaxy Clusters, Near and Far, Have a Lot in Common

NASA Astrophysics Data System (ADS)

2005-04-01

Using two orbiting X-ray telescopes, a team of international astronomers has examined distant galaxy clusters in order to compare them with their counterparts that are relatively close by. Speaking today at the RAS National Astronomy Meeting in Birmingham, Dr. Ben Maughan (Harvard-Smithsonian Center for Astrophysics), presented the results of this new analysis. The observations indicate that, despite the great expansion that the Universe has undergone since the Big Bang, galaxy clusters both local and distant have a great deal in common. This discovery could eventually lead to a better understanding of how to "weigh" these enormous structures, and, in so doing, answer important questions about the nature and structure of the Universe. Clusters of galaxies, the largest known gravitationally-bound objects, are the knots in the cosmic web of structure that permeates the Universe. Theoretical models make predictions about the number, distribution and properties of these clusters. Scientists can test and improve models of the Universe by comparing these predictions with observations. The most powerful way of doing this is to measure the masses of galaxy clusters, particularly those in the distant Universe. However, weighing galaxy clusters is extremely difficult. One relatively easy way to weigh a galaxy cluster is to use simple laws ("scaling relations") to estimate its weight from properties that are easy to observe, like its luminosity (brightness) or temperature. This is like estimating someone's weight from their height if you didn't have any scales. Over the last 3 years, a team of researchers, led by Ben Maughan, has observed 11 distant galaxy clusters with ESA's XMM-Newton and NASA's Chandra X-ray Observatory. The clusters have redshifts of z = 0.6-1.0, which corresponds to distances of 6 to 8 billion light years. This means that we see them as they were when the Universe was half its present age. The survey included two unusual systems, one in which two massive clusters are merging and another extremely massive cluster which appears very "relaxed" and undisturbed. The X-ray data allowed the scientists to measure the temperatures and luminosities of the gas in the clusters. They were then able to infer their total masses, which varied between 200 and 1,100 times the mass of our Milky Way galaxy. These measurements were then used to test whether galaxy clusters of different sizes and located at different distances from us are simply scaled versions of each other -- a condition known as being "self-similar." This is an important characteristic for astronomers to identify if they hope to get the true weights of galaxy clusters. "For example, chocolate bars are strongly self-similar," said Maughan. "If you shrank a king-size bar to a fun-size bar, they would be identical versions of each other but just different sizes." "However, if you shrank a castle to the size of a bungalow, they would be very different structures, despite being the same size. This means that they are not strongly self-similar objects." Another possible type of relationship between clusters is what scientists call "weakly self-similar." In this case, galaxy clusters in the distant universe and those nearby are almost identical to each other, but not exactly the same. (The only differences between them can be accounted for by the expansion of the Universe since the Big Bang.) Although astronomers have known for some time that galaxy clusters are not strongly self-similar, the question of whether or not they are weakly self-similar has remained open. The new results show that as long as astronomers take into account the continuous expansion of the Universe, then galaxy clusters are, in fact, weakly self-similar. This means that the same scaling relations used to weigh nearby galaxy clusters hold true for these very distant clusters. "Our results mean that weighing distant galaxy clusters could become as easy as converting from Fahrenheit to Celsius," said Maughan. "This will help to answer important questions about the nature and structure of the Universe." The other members of the team were: Laurence Jones (University of Birmingham, UK) Harald Ebeling (Institute for Astronomy, HI, USA), and Caleb Scharf (Columbia Astrophysics Laboratory, NY, USA). The observations were made with the European Photon Imaging Camera (EPIC) on XMM and the Advanced Camera for Imaging and Spectroscopy (ACIS) on Chandra. They were part of the WARPS survey of distant galaxy clusters detected by chance in observations made with the UK-US-Dutch ROSAT X-ray satellite. Additional information and images are available at: http://www.sr.bham.ac.uk/~habib/nampr/

Distant metastasis of intraosseous dentinogenic ghost cell tumour to the donor site of a bone graft

PubMed Central

Park, H-R; Min, J-H; Huh, K-H; Yi, W-J; Heo, M-S; Lee, S-S; Cho, Y-A

2013-01-01

A dentinogenic ghost cell tumour (DGCT) is an extremely rare odontogenic tumour which is considered as a solid, neoplastic variant of calcifying odontogenic cyst. Intraosseous DGCTs are more aggressive than extraosseous DGCTs and have a high propensity for local recurrence. This report describes a case of a diagnosis of recurrent DGCT at the primary site and a distant donor site. A 25-year-old female patient visited a dental hospital for a complaint of facial swelling for the previous month. Incisional biopsy was performed and the specimen was diagnosed as DGCT. Partial mandibulectomy for tumour resection and iliac bone graft was performed. 2 years later, the tumour recurred on the mandible and iliac bone. The recurrent lesion on the donor site was diagnosed as metastasized DGCT. This report highlights the possibility of distant metastasis occurring at a graft donor site. PMID:23420853

A portrait of the extreme solar system object 2012 DR30

NASA Astrophysics Data System (ADS)

Kiss, Cs.; Szabó, Gy.; Horner, J.; Conn, B. C.; Müller, T. G.; Vilenius, E.; Sárneczky, K.; Kiss, L. L.; Bannister, M.; Bayliss, D.; Pál, A.; Góbi, S.; Verebélyi, E.; Lellouch, E.; Santos-Sanz, P.; Ortiz, J. L.; Duffard, R.; Morales, N.

2013-07-01

2012 DR30 is a recently discovered solar system object on a unique orbit, with a high eccentricity of 0.9867, a perihelion distance of 14.54 AU, and a semi-major axis of 1109 AU, in this respect outscoring the vast majority of trans-Neptunian objects (TNOs). We performed Herschel/PACS and optical photometry to uncover the sizeand albedo of 2012 DR30, together with its thermal and surface properties. The body is 185 km in diameter and has a relatively low V-band geometric albedo of ~8%. Although the colours of the object indicate that 2012 DR30 is an RI taxonomy class TNO or Centaur, we detected an absorption feature in the Z-band that is uncommon among these bodies. A dynamical analysis of the target's orbit shows that 2012 DR30 moves on a relatively unstable orbit and was most likely only recently placed on its current orbit from the most distant and still highly unexplored regions of the solar system. If categorised on dynamical grounds 2012 DR30 is the largest Damocloid and/or high inclination Centaur observed so far. Herschel is an ESA space observatory with science instruments provided by European-led Principal Investigator consortia and with important participation from NASA.Appendices are available in electronic form at http://www.aanda.org

KENNEDY SPACE CENTER, FLA. - The master assembler, crane crew, removes a five-meter telescope in Cocoa Beach, Fla., for repair. The tracking telescope is part of the Distant Object Attitude Measurement System (DOAMS) that provides optical support for launches from KSC and Cape Canaveral.

NASA Image and Video Library

2003-08-25

KENNEDY SPACE CENTER, FLA. - The master assembler, crane crew, removes a five-meter telescope in Cocoa Beach, Fla., for repair. The tracking telescope is part of the Distant Object Attitude Measurement System (DOAMS) that provides optical support for launches from KSC and Cape Canaveral.

Emergency-vehicle VHF antenna

NASA Technical Reports Server (NTRS)

Anderson, R. E.; Carlson, A. W.; Lewis, J.

1977-01-01

Helical VHF antenna mounts on roof of moving vehicle to communicate with distant stations via earth satellites. Antenna requires no pointing and can provide two-way communication while vehicle moves at high speed. Device has proved extremely successful in electrocardiogram transmission tests between medical services vehicle and hospital emergency room.

Distant asteroids and Chiron

NASA Technical Reports Server (NTRS)

French, Linda M.; Vilas, Faith; Hartmann, William K.; Tholen, David J.

1989-01-01

Knowledge of the physical properties of distant asteroids (a greater than 3.3 AU) has grown dramatically over the past five years, due to systematic compositional and lighcurve studies. Most of these objects have red, dark surfaces, and their spectra show a reddening in spectral slope with heliocentric distance, implying a change in surface composition. Trojans for which near-opposition phase curve information is available appear to show little or no opposition effect, unlike any other dark solar system objects. The lightcurve amplitudes of Trojan and Hilda asteroids imply significantly more elongated shapes for these groups than for main-belt asteroids of comparable size. These recent observations are reviewed in the context of their implications for the formationan and subsequent evolution of the distant asteroids, and their interrelations with the main belt, Chiron, and comets.

Hubble and ESO's VLT provide unique 3D views of remote galaxies

NASA Astrophysics Data System (ADS)

2009-03-01

Astronomers have obtained exceptional 3D views of distant galaxies, seen when the Universe was half its current age, by combining the twin strengths of the NASA/ESA Hubble Space Telescope's acute eye, and the capacity of ESO's Very Large Telescope to probe the motions of gas in tiny objects. By looking at this unique "history book" of our Universe, at an epoch when the Sun and the Earth did not yet exist, scientists hope to solve the puzzle of how galaxies formed in the remote past. ESO PR Photo 10a/09 A 3D view of remote galaxies ESO PR Photo 10b/09 Measuring motions in 3 distant galaxies ESO PR Video 10a/09 Galaxies in collision For decades, distant galaxies that emitted their light six billion years ago were no more than small specks of light on the sky. With the launch of the Hubble Space Telescope in the early 1990s, astronomers were able to scrutinise the structure of distant galaxies in some detail for the first time. Under the superb skies of Paranal, the VLT's FLAMES/GIRAFFE spectrograph (ESO 13/02) -- which obtains simultaneous spectra from small areas of extended objects -- can now also resolve the motions of the gas in these distant galaxies (ESO 10/06). "This unique combination of Hubble and the VLT allows us to model distant galaxies almost as nicely as we can close ones," says François Hammer, who led the team. "In effect, FLAMES/GIRAFFE now allows us to measure the velocity of the gas at various locations in these objects. This means that we can see how the gas is moving, which provides us with a three-dimensional view of galaxies halfway across the Universe." The team has undertaken the Herculean task of reconstituting the history of about one hundred remote galaxies that have been observed with both Hubble and GIRAFFE on the VLT. The first results are coming in and have already provided useful insights for three galaxies. In one galaxy, GIRAFFE revealed a region full of ionised gas, that is, hot gas composed of atoms that have been stripped of one or several electrons. This is normally due to the presence of very hot, young stars. However, even after staring at the region for more than 11 days, Hubble did not detect any stars! "Clearly this unusual galaxy has some hidden secrets," says Mathieu Puech, lead author of one of the papers reporting this study. Comparisons with computer simulations suggest that the explanation lies in the collision of two very gas-rich spiral galaxies. The heat produced by the collision would ionise the gas, making it too hot for stars to form. Another galaxy that the astronomers studied showed the opposite effect. There they discovered a bluish central region enshrouded in a reddish disc, almost completely hidden by dust. "The models indicate that gas and stars could be spiralling inwards rapidly," says Hammer. This might be the first example of a disc rebuilt after a major merger (ESO 01/05). Finally, in a third galaxy, the astronomers identified a very unusual, extremely blue, elongated structure -- a bar -- composed of young, massive stars, rarely observed in nearby galaxies. Comparisons with computer simulations showed the astronomers that the properties of this object are well reproduced by a collision between two galaxies of unequal mass. "The unique combination of Hubble and FLAMES/GIRAFFE at the VLT makes it possible to model distant galaxies in great detail, and reach a consensus on the crucial role of galaxy collisions for the formation of stars in a remote past," says Puech. "It is because we can now see how the gas is moving that we can trace back the mass and the orbits of the ancestral galaxies relatively accurately. Hubble and the VLT are real ‘time machines' for probing the Universe's history", adds Sébastien Peirani, lead author of another paper reporting on this study. The astronomers are now extending their analysis to the whole sample of galaxies observed. "The next step will then be to compare this with closer galaxies, and so, piece together a picture of the evolution of galaxies over the past six to eight billion years, that is, over half the age of the Universe," concludes Hammer.

KSC-08pd2456

NASA Image and Video Library

2008-08-18

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, a technicians clean the radiator on the Wide Field Camera 3, or WFC3,that will be installed on NASA's Hubble Space Telescope. The radiator is the "outside" of WFC3 that will be exposed to space. It will expel heat out of Hubble and into space through black body radiation. WFC3 is part of the payload on space shuttle Atlantis' STS-125 mission for the fifth and final Hubble servicing flight to NASA's Hubble Space Telescope. As Hubble enters the last stage of its life, WFC3 will be Hubble's next evolutionary step, allowing Hubble to peer ever further into the mysteries of the cosmos. WFC3 will study a diverse range of objects and phenomena, from young and extremely distant galaxies, to much more nearby stellar systems, to objects within our very own solar system. WFC3 will take the place of Wide Field Planetary Camera 2, which astronauts will bring back to Earth aboard the shuttle. Launch of Atlantis is targeted at 1:34 a.m. EDT Oct. 8. Photo credit: NASA/Amanda Diller

KSC-08pd2460

NASA Image and Video Library

2008-08-18

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, the Wide Field Camera 3, or WFC3, waits to be transferred to the Super Lightweight Interchangeable Carrier. WFC3 is part of the payload on space shuttle Atlantis' STS-125 mission for the fifth and final Hubble servicing flight to NASA's Hubble Space Telescope. The part shown here is the radiator, the "outside" of WFC3 that will be exposed to space and will expel heat out of Hubble and into space through black body radiation. As Hubble enters the last stage of its life, WFC3 will be Hubble's next evolutionary step, allowing Hubble to peer ever further into the mysteries of the cosmos. WFC3 will study a diverse range of objects and phenomena, from young and extremely distant galaxies, to much more nearby stellar systems, to objects within our very own solar system. WFC3 will take the place of Wide Field Planetary Camera 2, which astronauts will bring back to Earth aboard the shuttle. Launch of Atlantis is targeted at 1:34 a.m. EDT Oct. 8. Photo credit: NASA/Amanda Diller

Multi-conjugated adaptive optics imaging of distant galaxies - a comparison of Gemini/GSAOI and VLT/HAWK-I data

NASA Astrophysics Data System (ADS)

Schirmer, Mischa; Garrel, Vincent; Sivo, Gaetano; Marin, Eduardo; Carrasco, Eleazar R.

2017-11-01

Multi-conjugated adaptive optics (MCAO) yield nearly diffraction-limited images at 2 μm wavelengths. Currently, Gemini Multi-Conjugate Adaptive Optics System (GeMS)/Gemini South Adaptive Optics Imager (GSAOI) at Gemini South is the only MCAO facility instrument at an 8-m telescope. Using real data, and for the first time, we investigate the gain in depth and signal-to-noise ratios (S/N) when MCAO is employed for Ks-band observations of distant galaxies. Our analysis is based on the Frontier Fields cluster MACS J0416.1-2403, observed with GeMS/GSAOI (near diffraction-limited) and compared against Very Large Telescope/HAWK-I (natural seeing) data. Using galaxy number counts, we show that the substantially increased thermal background and lower optical throughput of the MCAO unit are fully compensated for by the wavefront correction because the galaxy images can be measured in smaller apertures with less sky noise. We also performed a direct comparison of the S/N of sources detected in both data sets. For objects with intrinsic angular sizes corresponding to half the HAWK-I image seeing, the gain in S/N is 40 per cent. Even smaller objects experience a boost in S/N by up to a factor of 2.5 despite our suboptimal natural guide star configuration. The depth of the near diffraction limited images is more difficult to quantify than that of seeing limited images, due to a strong dependence on the intrinsic source profiles. Our results emphasize the importance of cooled MCAO systems for Ks-band observations with future, extremely large telescopes.

Orbit Modification of Earth-Crossing Asteroids/Comets Using Rendezvous Spacecraft and Laser Ablation

NASA Technical Reports Server (NTRS)

Park, Sang-Young; Mazanek, Daniel D.

2005-01-01

This report describes the approach and results of an end-to-end simulation to deflect a long-period comet (LPC) by using a rapid rendezvous spacecraft and laser ablation system. The laser energy required for providing sufficient deflection DELTA V and an analysis of possible intercept/rendezvous spacecraft trajectories are studied in this analysis. These problems minimize a weighted sum of the flight time and required propellant by using an advanced propulsion system. The optimal thrust-vector history and propellant mass to use are found in order to transfer a spacecraft from the Earth to a targeted celestial object. One goal of this analysis is to formulate an optimization problem for intercept/rendezvous spacecraft trajectories. One approach to alter the trajectory of the object in a highly controlled manner is to use pulsed laser ablative propulsion. A sufficiently intense laser pulse ablates the surface of a near-Earth object (NEO) by causing plasma blowoff. The momentum change from a single laser pulse is very small. However, the cumulative effect is very effective because the laser can interact with the object over long periods of time. The laser ablation technique can overcome the mass penalties associated with other nondisruptive approaches because no propellant is required to generate the DELTA V (the material of the celestial object is the propellant source). Additionally, laser ablation is effective against a wide range of surface materials and does not require any landing or physical attachment to the object. For diverting distant asteroids and comets, the power and optical requirements of a laser ablation system on or near the Earth may be too extreme to contemplate in the next few decades. A hybrid solution would be for a spacecraft to carry a laser as a payload to a particular celestial body. The spacecraft would require an advanced propulsion system capable of rapid rendezvous with the object and an extremely powerful electrical generator, which is likely needed for the propulsion system as well. The spacecraft would station-keep with the object at a small standoff distance while the laser ablation is performed.

Characterizing the Protostars in the Herschel Survey of Cygnus-X

NASA Astrophysics Data System (ADS)

Kirk, James; Hora, J. L.; Smith, H. A.; Herschel Cygnus-X Group

2014-01-01

The Cygnus-X complex is an extremely active region of massive star formation at a distance of ~1.4 kpc which can be studied with higher sensitivity and less confusion than more distant regions. The study of this region is important in improving our understanding of the formation processes and protostellar phases of massive stars. A previous Spitzer Legacy survey of Cygnus-X mapped the distributions of Class I and Class II YSOs within the region and studied the interaction between massive young stars and clusters of YSOs. Using data from the recent Herschel survey of the region, taken with the PACS and SPIRE instrument (70-500 microns), we are expanding this study of star formation to the youngest and most deeply embedded objects. Using these data we will expand the sample of massive protostars and YSOs in Cygnus-X, analyze the population of infrared dark clouds and their embedded objects, construct Spectral Energy Distributions (SEDs) using pre-existing Spitzer and near-IR data sets (1-500 microns), and fit these sources with models of protostars to derive luminosities and envelope masses. The derived luminosities and masses will enable us to create evolutionary diagrams and test models of high-mass star formation. We will also investigate what role OB associations, such as Cyg OB2, play in causing subsequent star formation in neighboring clouds, providing us with a comprehensive picture of star formation within this extremely active complex.

Disentangling Hadronic and Leptonic Cascade Scenarios from the Very-High-Energy Gamma-Ray Emission of Distant Hard-Spectrum Blazars

DOE PAGES

Takami, Hajime; Murase, Kohta; Dermer, Charles D.

2013-06-26

We show that recent data from the Fermi Large Area Telescope have revealed about a dozen distant hard-spectrum blazars that have very-high-energy (VHE; ≳ 100 eV) photons associated with them, but most of them have not yet been detected by imaging atmospheric Cherenkov Telescopes. Most of these high-energy gamma-ray spectra, like those of other extreme high-frequency peaked BL Lac objects, can be well explained either by gamma rays emitted at the source or by cascades induced by ultra-high-energy cosmic rays, as we show specifically for KUV 00311–1938. We consider the prospects for detection of the VHE sources by the plannedmore » Cherenkov Telescope Array (CTA) and show how it can distinguish the two scenarios by measuring the integrated flux above ~500 GeV (depending on source redshift) for several luminous sources with z ≲ 1 in the sample. Strong evidence for the origin of ultra-high-energy cosmic rays could be obtained from VHE observations with CTA. Depending on redshift, if the often quoted redshift of KUV 00311–1938 (z = 0.61) is believed, then preliminary H.E.S.S. data favor cascades induced by ultra-high-energy cosmic rays. Lastly, accurate redshift measurements of hard-spectrum blazars are essential for this study.« less

Vacuum deposition of iridium on large astronomical mirrors for use in the far UV

NASA Technical Reports Server (NTRS)

Herzig, H.; Spencer, R. S.

1982-01-01

An iridium coating has been deposited by electron-beam evaporation on a 0.91-m mirror which serves as the telescope primary of a sounding rocket instrument for far-UV spectrometry. The evaporation was carried out by applying 8 kV at 400 mA to the electron gun. Zone refined Ir of 99.99% purity was used, and the electron beam was electromagnetically swept over the surface of the evaporant. Under these conditions, deposition rates of 0.55 A/sec were achieved. The reflectance distribution achieved at a wavelength of 584 A was extremely uniform; the mean reflectance was 21.2% with a standard deviation of only 0.3%. This represents a substantial improvement over Al + MgF2 and Al + LiF coatings for applications involving multiple reflections and weak signals, as might be expected in a high-resolution spectrograph studying distant celestial objects.

APEX Snaps First Close-up of Star Factories in Distant Universe

NASA Astrophysics Data System (ADS)

2010-03-01

For the first time, astronomers have made direct measurements of the size and brightness of regions of star-birth in a very distant galaxy, thanks to a chance discovery with the APEX telescope. The galaxy is so distant, and its light has taken so long to reach us, that we see it as it was 10 billion years ago. A cosmic "gravitational lens" is magnifying the galaxy, giving us a close-up view that would otherwise be impossible. This lucky break reveals a hectic and vigorous star-forming life for galaxies in the early Universe, with stellar nurseries forming one hundred times faster than in more recent galaxies. The research is published online today in the journal Nature. Astronomers were observing a massive galaxy cluster [1] with the Atacama Pathfinder Experiment (APEX) telescope, using submillimetre wavelengths of light, when they found a new and uniquely bright galaxy, more distant than the cluster and the brightest very distant galaxy ever seen at submillimetre wavelengths. It is so bright because the cosmic dust grains in the galaxy are glowing after being heated by starlight. The new galaxy has been given the name SMM J2135-0102. "We were stunned to find a surprisingly bright object that wasn't at the expected position. We soon realised it was a previously unknown and more distant galaxy being magnified by the closer galaxy cluster," says Carlos De Breuck from ESO, a member of the team. De Breuck was making the observations at the APEX telescope on the plateau of Chajnantor at an altitude of 5000 m in the Chilean Andes. The new galaxy SMM J2135-0102 is so bright because of the massive galaxy cluster that lies in the foreground. The vast mass of this cluster bends the light of the more distant galaxy, acting as a gravitational lens [2]. As with a telescope, it magnifies and brightens our view of the distant galaxy. Thanks to a fortuitous alignment between the cluster and the distant galaxy, the latter is strongly magnified by a factor of 32. "The magnification reveals the galaxy in unprecedented detail, even though it is so distant that its light has taken about 10 billion years to reach us," explains Mark Swinbank from Durham University, lead author of the paper reporting the discovery. "In follow-up observations with the Submillimeter Array telescope, we've been able to study the clouds where stars are forming in the galaxy with great precision." The magnification means that the star-forming clouds can be picked out in the galaxy, down to a scale of only a few hundred light-years - almost down to the size of giant clouds in our own Milky Way. To see this level of detail without the help of the gravitational lens would need future telescopes such as ALMA (the Atacama Large Millimeter/submillimeter Array), which is currently under construction on the same plateau as APEX. This lucky discovery has therefore given astronomers a unique preview of the science that will be possible in a few years time. These "star factories" are similar in size to those in the Milky Way, but one hundred times more luminous, suggesting that star formation in the early life of these galaxies is a much more vigorous process than typically found in galaxies that lie nearer to us in time and space. In many ways, the clouds look more similar to the densest cores of star-forming clouds in the nearby Universe. "We estimate that SMM J2135-0102 is producing stars at a rate that is equivalent to about 250 Suns per year," says de Breuck. "The star formation in its large dust clouds is unlike that in the nearby Universe, but our observations also suggest that we should be able to use similar underlying physics from the densest stellar nurseries in nearby galaxies to understand star birth in these more distant galaxies." Notes [1] Galaxy clusters are among the most massive objects in the Universe kept together by gravity. They are composed of hundreds to thousands of galaxies, which make up to only about a tenth of their total mass. The bulk of their mass, which amounts to up to a million billion [1015] times the mass of our Sun, is composed of hot gas and dark matter. In this case, the cluster being observed has the designation MACS J2135-010217 (or MACS J213512.10-010258.5), and is at a distance of about four billion light-years. [2] Gravitational lensing is an effect forecast by Albert Einstein's theory of general relativity. Due to their gigantic mass and their intermediate position between us and very distant galaxies, galaxy clusters act as extremely efficient gravitational lenses, bending the light coming from background galaxies. Depending on the cluster mass distribution a host of interesting effects are produced, such as magnification, shape distortions, giant arcs, and multiple images of the same source. More information This research was presented in a paper, "Intense star formation within resolved compact regions in a galaxy at z=2.3" (A. M. Swinbank et al., DOI 10.1038/nature08880) to appear online in Nature today. The team is composed of A. M. Swinbank, I. Smail, J. Richard, A. C. Edge, and K. E. K. Coppin (Institute for Computational Cosmology, Durham University, UK), S. Longmore, R. Blundell, M. Gurwell, and D. Wilner (Harvard-Smithsonian Center For Astrophysics, USA), A. I. Harris and L. J. Hainline (Department of Astronomy, University of Maryland, USA), A.J. Baker (Department of Physics and Astronomy, Rutgers, University of New Jersey, USA), C. De Breuck, A. Lundgren and G. Siringo (ESO), R. J. Ivison (UKATC and Royal Observatory of Edinburgh, UK), P. Cox, M. Krips and R. Neri (Institut de Radio Astronomie Millimétrique, France), B. Siana (California Institute of Technology, USA), D. P. Stark (Institute of Astronomy, University of Cambridge, UK), and J. D. Younger (Institute for Advanced Study, USA). The Atacama Pathfinder Experiment (APEX) telescope is a 12-metre telescope, located at 5100 m altitude on the arid plateau of Chajnantor in the Chilean Andes. APEX operates at millimetre and submillimetre wavelengths. This wavelength range is a relatively unexplored frontier in astronomy, requiring advanced detectors and an extremely high and dry observatory site, such as Chajnantor. APEX, the largest submillimetre-wave telescope operating in the southern hemisphere, is a collaboration between the Max Planck Institute for Radio Astronomy, the Onsala Space Observatory and ESO. Operation of APEX at Chajnantor is entrusted to ESO. APEX is a "pathfinder" for ALMA - it is based on a prototype antenna constructed for the ALMA project, it is located on the same plateau and will find many targets that ALMA will be able to study in extreme detail. ESO, the European Southern Observatory, is the foremost intergovernmental astronomy organisation in Europe and the world's most productive astronomical observatory. It is supported by 14 countries: Austria, Belgium, the Czech Republic, Denmark, France, Finland, Germany, Italy, the Netherlands, Portugal, Spain, Sweden, Switzerland and the United Kingdom. ESO carries out an ambitious programme focused on the design, construction and operation of powerful ground-based observing facilities enabling astronomers to make important scientific discoveries. ESO also plays a leading role in promoting and organising cooperation in astronomical research. ESO operates three unique world-class observing sites in Chile: La Silla, Paranal and Chajnantor. At Paranal, ESO operates the Very Large Telescope, the world's most advanced visible-light astronomical observatory and VISTA, the world's largest survey telescope. ESO is the European partner of a revolutionary astronomical telescope ALMA, the largest astronomical project in existence. ESO is currently planning a 42-metre European Extremely Large optical/near-infrared Telescope, the E-ELT, which will become "the world's biggest eye on the sky".

Necessary and sufficient criterion for extremal quantum correlations in the simplest Bell scenario

NASA Astrophysics Data System (ADS)

Ishizaka, Satoshi

2018-05-01

In the study of quantum nonlocality, one obstacle is that the analytical criterion for identifying the boundaries between quantum and postquantum correlations has not yet been given, even in the simplest Bell scenario. We propose a plausible, analytical, necessary and sufficient condition ensuring that a nonlocal quantum correlation in the simplest scenario is an extremal boundary point. Our extremality condition amounts to certifying an information-theoretical quantity; the probability of guessing a measurement outcome of a distant party optimized using any quantum instrument. We show that this quantity can be upper and lower bounded from any correlation in a device-independent way, and we use numerical calculations to confirm that coincidence of the upper and lower bounds appears to be necessary and sufficient for the extremality.

The future of stellar occultations by distant solar system bodies: Perspectives from the Gaia astrometry and the deep sky surveys

NASA Astrophysics Data System (ADS)

Camargo, J. I. B.; Desmars, J.; Braga-Ribas, F.; Vieira-Martins, R.; Assafin, M.; Sicardy, B.; Bérard, D.; Benedetti-Rossi, G.

2018-05-01

Distant objects in the solar system are crucial to better understand the history and evolution of its outskirts. The stellar occultation technique allows the determination of their sizes and shapes with kilometric accuracy, a detailed investigation of their immediate vicinities, as well as the detection of tenuous atmospheres. The prediction of such events is a key point in this study, and yet accurate enough predictions are available to a handful of objects only. In this work, we briefly discuss the dramatic impact that both the astrometry from the Gaia space mission and the deep sky surveys - the Large Synoptic Survey Telescope in particular - will have on the prediction of stellar occultations and how they may influence the future of the study of distant small solar system bodies through this technique.

Do pet dogs (Canis familiaris) follow ostensive and non-ostensive human gaze to distant space and to objects?

PubMed

Duranton, Charlotte; Range, Friederike; Virányi, Zsófia

2017-07-01

Dogs are renowned for being skilful at using human-given communicative cues such as pointing. Results are contradictory, however, when it comes to dogs' following human gaze, probably due to methodological discrepancies. Here we investigated whether dogs follow human gaze to one of two food locations better than into distant space even after comparable pre-training. In Experiments 1 and 2, the gazing direction of dogs was recorded in a gaze-following into distant space and in an object-choice task where no choice was allowed, in order to allow a direct comparison between tasks, varying the ostensive nature of the gazes. We found that dogs only followed repeated ostensive human gaze into distant space, whereas they followed all gaze cues in the object-choice task. Dogs followed human gaze better in the object-choice task than when there was no obvious target to look at. In Experiment 3, dogs were tested in another object-choice task and were allowed to approach a container. Ostensive cues facilitated the dogs' following gaze with gaze as well as their choices: we found that dogs in the ostensive group chose the indicated container at chance level, whereas they avoided this container in the non-ostensive group. We propose that dogs may perceive the object-choice task as a competition over food and may interpret non-ostensive gaze as an intentional cue that indicates the experimenter's interest in the food location she has looked at. Whether ostensive cues simply mitigate the competitive perception of this situation or they alter how dogs interpret communicative gaze needs further investigation. Our findings also show that following gaze with one's gaze and actually choosing one of the two containers in an object-choice task need to be considered as different variables. The present study clarifies a number of questions related to gaze-following in dogs and adds to a growing body of evidence showing that human ostensive cues can strongly modify dog behaviour.

Propagation and Detection of Neutrinos from Distant Objects

NASA Astrophysics Data System (ADS)

Bottino, A.; Kim, C. W.; Kim, Jewan; Lam, W. P.

We discuss how an initial composition of wave packets representing the neutrinos, emitted by distant objects such as supernovae, is modified as the neutrinos travel a long distance to the earth and how these modifications affect the detection of such neutrinos. In particular, observed neutrino masses are shown to depend on the mass square difference of the i-th and j-th flavors i.e., mi2 - mj2, L (the distance traveled), and a resolution time of the detector as well as on how neutrinos emerge from the star.

Driving many distant atoms into high-fidelity steady state entanglement via Lyapunov control.

PubMed

Li, Chuang; Song, Jie; Xia, Yan; Ding, Weiqiang

2018-01-22

Based on Lyapunov control theory in closed and open systems, we propose a scheme to generate W state of many distant atoms in the cavity-fiber-cavity system. In the closed system, the W state is generated successfully even when the coupling strength between the cavity and fiber is extremely weak. In the presence of atomic spontaneous emission or cavity and fiber decay, the photon-measurement and quantum feedback approaches are proposed to improve the fidelity, which enable efficient generation of high-fidelity W state in the case of large dissipation. Furthermore, the time-optimal Lyapunov control is investigated to shorten the evolution time and improve the fidelity in open systems.

USSR and Eastern Europe Scientific Abstracts, Geophysics, Astronomy and Space, Number 393

DTIC Science & Technology

1977-04-01

Pankov, "A Voice from Distant Stars"] [Excerpt] During recent years radioastronomy has made it possible to detect extremely "dark" phenomena and...Earlier in radioastronomy it was most common to use apparatus oper- ating on radio tubes and semiconductor crystals. But such apparatus has a serious

C III] Emission in Star-forming Galaxies Near and Far

NASA Astrophysics Data System (ADS)

Rigby, J. R.; Bayliss, M. B.; Gladders, M. D.; Sharon, K.; Wuyts, E.; Dahle, H.; Johnson, T.; Peña-Guerrero, M.

2015-11-01

We measure [C iii] 1907, C iii] 1909 Å emission lines in 11 gravitationally lensed star-forming galaxies at z ˜ 1.6-3, finding much lower equivalent widths than previously reported for fainter lensed galaxies. While it is not yet clear what causes some galaxies to be strong C iii] emitters, C iii] emission is not a universal property of distant star-forming galaxies. We also examine C iii] emission in 46 star-forming galaxies in the local universe, using archival spectra from GHRS, FOS, and STIS on HST and IUE. Twenty percent of these local galaxies show strong C iii] emission, with equivalent widths < -5 Å. Three nearby galaxies show C iii] emission equivalent widths as large as the most extreme emitters yet observed in the distant universe; all three are Wolf-Rayet galaxies. At all redshifts, strong C iii] emission may pick out low-metallicity galaxies experiencing intense bursts of star formation. Such local C iii] emitters may shed light on the conditions of star formation in certain extreme high-redshift galaxies.

C III] Emission in Star-Forming Galaxies Near and Far

NASA Technical Reports Server (NTRS)

Rigby, J, R.; Bayliss, M. B.; Gladders, M. D.; Sharon, K.; Wuyts, E.; Dahle, H.; Johnson, T.; Pena-Guerrero, M.

2015-01-01

We measure C III Lambda Lambda 1907, 1909 Angstrom emission lines in eleven gravitationally-lensed star-forming galaxies at zeta at approximately 1.6-3, finding much lower equivalent widths than previously reported for fainter lensed galaxies (Stark et al. 2014). While it is not yet clear what causes some galaxies to be strong C III] emitters, C III] emission is not a universal property of distant star-forming galaxies. We also examine C III] emission in 46 star-forming galaxies in the local universe, using archival spectra from GHRS, FOS, and STIS on HST, and IUE. Twenty percent of these local galaxies show strong C III] emission, with equivalent widths less than -5 Angstrom. Three nearby galaxies show C III] emission equivalent widths as large as the most extreme emitters yet observed in the distant universe; all three are Wolf-Rayet galaxies. At all redshifts, strong C III] emission may pick out low-metallicity galaxies experiencing intense bursts of star formation. Such local C III] emitters may shed light on the conditions of star formation in certain extreme high-redshift galaxies.

Talking Climate Science in a Changing Media Landscape

NASA Astrophysics Data System (ADS)

Cullen, H. M.

2014-12-01

Founded in 2008 by leading scientists and communications experts at Princeton, Yale and Stanford, Climate Central brings together award-winning journalists and internationally recognized scientists to report the science and impacts of climate change through its research and journalism programs. Climate Central works to tackle the misperception that climate change is a distant thing - affecting other people and other places - by demonstrating the local and personal impacts of global warming. This talk will focus on describing three important Climate Central initiatives. First, our Climate Matters program delivers localized climate information at the regional and local level to weathercasters around the U.S., providing ready-to-use, broadcast quality graphics and analyses that put climate change in a local context. After three years, the program has grown from a pilot with just one TV meteorologist in Columbia, South Carolina to a network of more than 150 weathercasters across the country. Climate Central was also closely involved in the development and production of Years of Living Dangerously - a 9-part global warming documentary that premiered in April 2014. Finally, the World Weather Attribution project is a new initiative that aims to identify the human fingerprint in certain types of extreme weather events, including sea level rise and its contribution to storm surges, extreme heat events, heavy rainfall events/flooding, and drought. Our goal is to objectively and transparently assess certain extreme events and equip journalists and scientists with the tools to provide the larger global warming context in real-time while there is still media interest.

IGR J12319-0749: Evidence for Another Extreme Blazar Found with INTEGRAL

NASA Technical Reports Server (NTRS)

Bassani, L.; Landi, R.; Marshall, F. E.; Malizia, A.; Bazzano, A.; Bird, A. J.; Gehrels, N.; Ubertini, P.; Masetti, N.

2012-01-01

We report on the identification of a new soft gamma-ray source, IGR J12319-0749, detected with the IBIS imager on board the INTEGRAL satellite. The source, which has an observed 20-100 keV flux of approx 8.3 × 10(exp -12) erg/sq. cm/ s, is spatially coincident with an active galactic nucleus (AGN) at redshift z = 3.12. The broad-band continuum, obtained by combining XRT and IBIS data, is flat (Gamma = 1.3) with evidence for a spectral break around 25 keV (100 keV in the source restframe). X-ray observations indicate flux variability, which is also supported by a comparison with a previous ROSAT measurement. IGR J12319-0749 is also a radio-emitting object likely characterised by a flat spectrum and high radio loudness; optically it is a broad-line emitting object with a massive black hole (2.8 × 10(exp 9) solar masses) at its centre. The source spectral energy distribution is similar to another high-redshift blazar, 225155+2217 at z = 3.668: both objects are bright, with a high accretion disk luminosity and a Compton peak located in the hard X-ray/soft gamma-ray band. IGR J12319-0749 is likely the second-most distant blazar detected so far by INTEGRAL.

IGR J12319-0749: Evidence for Another Extreme Blazar Found with INTEGRAL

NASA Technical Reports Server (NTRS)

Bassani, L.; Landi, R.; Marshall, F. E.; Malizia, A.; Bazzano, A.; Bird, A. J.; Gehrels, N.; Ubertini, P.; Masetti, N.

2012-01-01

We report on the identification of a new soft gamma-ray source, IGR J12319 C0749, detected with the IBIS imager on board the INTEGRAL satellite. The source, which has an observed 20 C100 keV flux of 8.3 10.12 erg cm.2 s.1, is spatially coincident with an AGN at redshift z = 3.12. The broad-band continuum, obtained by combining XRT and IBIS data, is flat ( =1.3) with evidence for a spectral break around 25 keV (100 keV in the source rest frame). X-ray observations indicate flux variability which is further supported by a comparison with a previous ROSAT measurement. IGR J12319 C0749 is also a radio emitting object likely characterized by a flat spectrum and high radio loudness; optically it is a broad-line emitting object with a massive black hole (2.8 109 solar masses) at its center. The source Spectral Energy Distribution is similar to another high redshift blazar, 225155+2217 at z = 3.668: both objects are bright, with a large accretion disk luminosity and a Compton peak located in the hard X-ray/soft gamma-ray band. IGR J12319 C0749 is likely the second most distant blazar detected so far by INTEGRAL.

The Current Status of Religious Coexistence and Education in Bosnia and Herzegovina. USIPeace Briefing

ERIC Educational Resources Information Center

Stuebner, Renata

2009-01-01

Despite 15 years of sporadic efforts, religion today in Bosnia and Herzegovina is more of a hindrance than a help to promoting peaceful coexistence among the region's various ethnic and religious groups. Polarization and extremism make religions other than one's own even more distant, strange and threatening. Physical interaction that existed…

High Resolution Integral Field Spectroscopy of Europa's Sodium Clouds: Evidence for a Component with Origins in Iogenic Plasma.

NASA Astrophysics Data System (ADS)

Schmidt, C.; Johnson, R. E.; Mendillo, M.; Baumgardner, J. L.; Moore, L.; O'Donoghue, J.; Leblanc, F.

2015-12-01

With the object of constraining Iogenic contributions and identifying drivers for variability, we report new observations of neutral sodium in Europa's exosphere. An R~20000 integral field spectrograph at McDonald Observatory is used to generate Doppler maps of sodium cloud structures with a resolution of 2.8 km/s/pixel. In the five nights of observations since 2011, measurements on UT 6.15-6.31 May 2015 uniquely feature fast (10s of km/s) neutral sodium clouds extending nearly 100 Europa radii, more distant than in any previous findings. During these measurements, the satellite geometry was favorable for the transfer of Na from Io to Europa, located at 1:55 to 4:00 and 3:38 to 4:39 Jovian local time, respectively. Eastward emission (away from Jupiter) extends 10-20 Europa radii retaining the moon's rest velocity, while westward emission blue-shifts with distance, and a broad range of velocities are measured, reaching at least 70 km/s at 80 Europa radii. These cloud features are distinct from Io's "banana" and "stream" features, the distant Jupiter-orbiting nebula, and from terrestrial OH and Na contaminant emissions. Io's production was quiescent during this observation, following an extremely active phase in February 2015. These results are consistent with previous findings that Europa's Na exosphere has peak emission between midnight and dawn Jovian local time and support the idea that sodium escape from Io can significantly enhance the emission intensity measured at Europa.

[The evolution of heat shock genes and expression patterns of heat shock proteins in the species from temperature contrasting habitats].

PubMed

Garbuz, D G; Evgen’ev, M B

2017-01-01

Heat shock genes are the most evolutionarily ancient among the systems responsible for adaptation of organisms to a harsh environment. The encoded proteins (heat shock proteins, Hsps) represent the most important factors of adaptation to adverse environmental conditions. They serve as molecular chaperones, providing protein folding and preventing aggregation of damaged cellular proteins. Structural analysis of the heat shock genes in individuals from both phylogenetically close and very distant taxa made it possible to reveal the basic trends of the heat shock gene organization in the context of adaptation to extreme conditions. Using different model objects and nonmodel species from natural populations, it was demonstrated that modulation of the Hsps expression during adaptation to different environmental conditions could be achieved by changing the number and structural organization of heat shock genes in the genome, as well as the structure of their promoters. It was demonstrated that thermotolerant species were usually characterized by elevated levels of Hsps under normal temperature or by the increase in the synthesis of these proteins in response to heat shock. Analysis of the heat shock genes in phylogenetically distant organisms is of great interest because, on one hand, it contributes to the understanding of the molecular mechanisms of evolution of adaptogenes and, on the other hand, sheds the light on the role of different Hsps families in the development of thermotolerance and the resistance to other stress factors.

Do pet dogs (Canis familiaris) follow ostensive and non-ostensive human gaze to distant space and to objects?

PubMed Central

Range, Friederike; Virányi, Zsófia

2017-01-01

Dogs are renowned for being skilful at using human-given communicative cues such as pointing. Results are contradictory, however, when it comes to dogs' following human gaze, probably due to methodological discrepancies. Here we investigated whether dogs follow human gaze to one of two food locations better than into distant space even after comparable pre-training. In Experiments 1 and 2, the gazing direction of dogs was recorded in a gaze-following into distant space and in an object-choice task where no choice was allowed, in order to allow a direct comparison between tasks, varying the ostensive nature of the gazes. We found that dogs only followed repeated ostensive human gaze into distant space, whereas they followed all gaze cues in the object-choice task. Dogs followed human gaze better in the object-choice task than when there was no obvious target to look at. In Experiment 3, dogs were tested in another object-choice task and were allowed to approach a container. Ostensive cues facilitated the dogs’ following gaze with gaze as well as their choices: we found that dogs in the ostensive group chose the indicated container at chance level, whereas they avoided this container in the non-ostensive group. We propose that dogs may perceive the object-choice task as a competition over food and may interpret non-ostensive gaze as an intentional cue that indicates the experimenter's interest in the food location she has looked at. Whether ostensive cues simply mitigate the competitive perception of this situation or they alter how dogs interpret communicative gaze needs further investigation. Our findings also show that following gaze with one's gaze and actually choosing one of the two containers in an object-choice task need to be considered as different variables. The present study clarifies a number of questions related to gaze-following in dogs and adds to a growing body of evidence showing that human ostensive cues can strongly modify dog behaviour. PMID:28791164

KSC-08pd2465

NASA Image and Video Library

2008-08-18

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, technicians observe as the Wide Field Camera 3, or WFC3, is rotated. The WFC3 will be transferred to the Super Lightweight Interchangeable Carrier. WFC3 is part of the payload on space shuttle Atlantis' STS-125 mission for the fifth and final Hubble servicing flight to NASA's Hubble Space Telescope. The curved edge shown at the back is the radiator, the "outside" of WFC3 that will be exposed to space and will expel heat out of Hubble and into space through black body radiation. As Hubble enters the last stage of its life, WFC3 will be Hubble's next evolutionary step, allowing Hubble to peer ever further into the mysteries of the cosmos. WFC3 will study a diverse range of objects and phenomena, from young and extremely distant galaxies, to much more nearby stellar systems, to objects within our very own solar system. WFC3 will take the place of Wide Field Planetary Camera 2, which astronauts will bring back to Earth aboard the shuttle. Launch of Atlantis is targeted at 1:34 a.m. EDT Oct. 8. Photo credit: NASA/Amanda Diller

KSC-08pd2466

NASA Image and Video Library

2008-08-18

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, technicians observe as the Wide Field Camera 3, or WFC3, is rotated to vertical. The WFC3 will be transferred to the Super Lightweight Interchangeable Carrier. WFC3 is part of the payload on space shuttle Atlantis' STS-125 mission for the fifth and final Hubble servicing flight to NASA's Hubble Space Telescope. The curved edge shown at top is the radiator, the "outside" of WFC3 that will be exposed to space and will expel heat out of Hubble and into space through black body radiation. As Hubble enters the last stage of its life, WFC3 will be Hubble's next evolutionary step, allowing Hubble to peer ever further into the mysteries of the cosmos. WFC3 will study a diverse range of objects and phenomena, from young and extremely distant galaxies, to much more nearby stellar systems, to objects within our very own solar system. WFC3 will take the place of Wide Field Planetary Camera 2, which astronauts will bring back to Earth aboard the shuttle. Launch of Atlantis is targeted at 1:34 a.m. EDT Oct. 8. Photo credit: NASA/Amanda Diller

KSC-08pd2467

NASA Image and Video Library

2008-08-18

CAPE CANAVERAL, Fla. – After rotation of the Wide Field Camera 3 (background left), or WFC3, in the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, technicians check the data. The WFC3 will be transferred to the Super Lightweight Interchangeable Carrier. WFC3 is part of the payload on space shuttle Atlantis' STS-125 mission for the fifth and final Hubble servicing flight to NASA's Hubble Space Telescope. The curved edge shown at top is the radiator, the "outside" of WFC3 that will be exposed to space and will expel heat out of Hubble and into space through black body radiation. As Hubble enters the last stage of its life, WFC3 will be Hubble's next evolutionary step, allowing Hubble to peer ever further into the mysteries of the cosmos. WFC3 will study a diverse range of objects and phenomena, from young and extremely distant galaxies, to much more nearby stellar systems, to objects within our very own solar system. WFC3 will take the place of Wide Field Planetary Camera 2, which astronauts will bring back to Earth aboard the shuttle. Launch of Atlantis is targeted at 1:34 a.m. EDT Oct. 8. Photo credit: NASA/Amanda Diller

KSC-08pd2464

NASA Image and Video Library

2008-08-18

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, the Wide Field Camera 3, or WFC3, has been rotated. The WFC3 will be transferred to the Super Lightweight Interchangeable Carrier. WFC3 is part of the payload on space shuttle Atlantis' STS-125 mission for the fifth and final Hubble servicing flight to NASA's Hubble Space Telescope. The curved edge shown at top is the radiator, the "outside" of WFC3 that will be exposed to space and will expel heat out of Hubble and into space through black body radiation. As Hubble enters the last stage of its life, WFC3 will be Hubble's next evolutionary step, allowing Hubble to peer ever further into the mysteries of the cosmos. WFC3 will study a diverse range of objects and phenomena, from young and extremely distant galaxies, to much more nearby stellar systems, to objects within our very own solar system. WFC3 will take the place of Wide Field Planetary Camera 2, which astronauts will bring back to Earth aboard the shuttle. Launch of Atlantis is targeted at 1:34 a.m. EDT Oct. 8. Photo credit: NASA/Amanda Diller

KSC-08pd2461

NASA Image and Video Library

2008-08-18

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, technicians wait for the rotation of the Wide Field Camera 3, or WFC3, in order to attach a crane. The WFC3 will be transferred to the Super Lightweight Interchangeable Carrier. WFC3 is part of the payload on space shuttle Atlantis' STS-125 mission for the fifth and final Hubble servicing flight to NASA's Hubble Space Telescope. The part shown here is the radiator, the "outside" of WFC3 that will be exposed to space and will expel heat out of Hubble and into space through black body radiation. As Hubble enters the last stage of its life, WFC3 will be Hubble's next evolutionary step, allowing Hubble to peer ever further into the mysteries of the cosmos. WFC3 will study a diverse range of objects and phenomena, from young and extremely distant galaxies, to much more nearby stellar systems, to objects within our very own solar system. WFC3 will take the place of Wide Field Planetary Camera 2, which astronauts will bring back to Earth aboard the shuttle. Launch of Atlantis is targeted at 1:34 a.m. EDT Oct. 8. Photo credit: NASA/Amanda Diller

KSC-08pd2462

NASA Image and Video Library

2008-08-18

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, technicians wait for the rotation of the Wide Field Camera 3, or WFC3, in order to attach a crane. The WFC3 will be transferred to the Super Lightweight Interchangeable Carrier. WFC3 is part of the payload on space shuttle Atlantis' STS-125 mission for the fifth and final Hubble servicing flight to NASA's Hubble Space Telescope. The curved edge shown at left is the radiator, the "outside" of WFC3 that will be exposed to space and will expel heat out of Hubble and into space through black body radiation. As Hubble enters the last stage of its life, WFC3 will be Hubble's next evolutionary step, allowing Hubble to peer ever further into the mysteries of the cosmos. WFC3 will study a diverse range of objects and phenomena, from young and extremely distant galaxies, to much more nearby stellar systems, to objects within our very own solar system. WFC3 will take the place of Wide Field Planetary Camera 2, which astronauts will bring back to Earth aboard the shuttle. Launch of Atlantis is targeted at 1:34 a.m. EDT Oct. 8. Photo credit: NASA/Amanda Diller

KSC-08pd2463

NASA Image and Video Library

2008-08-18

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, technicians stand by as the Wide Field Camera 3, or WFC3, is rotated. The WFC3 will be transferred to the Super Lightweight Interchangeable Carrier. WFC3 is part of the payload on space shuttle Atlantis' STS-125 mission for the fifth and final Hubble servicing flight to NASA's Hubble Space Telescope. The curved edge shown at left is the radiator, the "outside" of WFC3 that will be exposed to space and will expel heat out of Hubble and into space through black body radiation. As Hubble enters the last stage of its life, WFC3 will be Hubble's next evolutionary step, allowing Hubble to peer ever further into the mysteries of the cosmos. WFC3 will study a diverse range of objects and phenomena, from young and extremely distant galaxies, to much more nearby stellar systems, to objects within our very own solar system. WFC3 will take the place of Wide Field Planetary Camera 2, which astronauts will bring back to Earth aboard the shuttle. Launch of Atlantis is targeted at 1:34 a.m. EDT Oct. 8. Photo credit: NASA/Amanda Diller

KSC-08pd2455

NASA Image and Video Library

2008-08-18

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, a technician cleans the edge of the radiator on the Wide Field Camera 3, or WFC3,that will be installed on NASA's Hubble Space Telescope. The radiator is the "outside" of WFC3 that will be exposed to space. It will expel heat out of Hubble and into space through black body radiation. WFC3 is part of the payload on space shuttle Atlantis' STS-125 mission for the fifth and final Hubble servicing flight to NASA's Hubble Space Telescope. As Hubble enters the last stage of its life, WFC3 will be Hubble's next evolutionary step, allowing Hubble to peer ever further into the mysteries of the cosmos. WFC3 will study a diverse range of objects and phenomena, from young and extremely distant galaxies, to much more nearby stellar systems, to objects within our very own solar system. WFC3 will take the place of Wide Field Planetary Camera 2, which astronauts will bring back to Earth aboard the shuttle. Launch of Atlantis is targeted at 1:34 a.m. EDT Oct. 8. Photo credit: NASA/Amanda Diller

KSC-08pd2468

NASA Image and Video Library

2008-08-18

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, a technician guides a crane for attachment to the radiator on the Wide Field Camera 3, or WFC3. The WFC3 will be transferred to the Super Lightweight Interchangeable Carrier. WFC3 is part of the payload on space shuttle Atlantis' STS-125 mission for the fifth and final Hubble servicing flight to NASA's Hubble Space Telescope. The radiator is the "outside" of WFC3 that will be exposed to space and will expel heat out of Hubble and into space through black body radiation. As Hubble enters the last stage of its life, WFC3 will be Hubble's next evolutionary step, allowing Hubble to peer ever further into the mysteries of the cosmos. WFC3 will study a diverse range of objects and phenomena, from young and extremely distant galaxies, to much more nearby stellar systems, to objects within our very own solar system. WFC3 will take the place of Wide Field Planetary Camera 2, which astronauts will bring back to Earth aboard the shuttle. Launch of Atlantis is targeted at 1:34 a.m. EDT Oct. 8. Photo credit: NASA/Amanda Diller

Extreme Wolf-Rayet Galaxies with HST/COS: Understanding CIII] Emission in the Reionization Era

NASA Astrophysics Data System (ADS)

Stark, Daniel

2017-08-01

The first deep spectra of reionization-era galaxies have revealed strong UV nebular emission in high-ionization lines. This is in striking contrast to massive galaxies at lower redshifts, where emission from CIII], OIII], HeII, and CIV is rarely seen. These lines will likely be the only probe available for the most distant galaxies JWST will detect; but we are still unprepared to interpret them. Modeling predicts that intense UV nebular emission can only be produced below a tenth solar metallicity. However, recent HST/COS observations of local galaxies suggest that extreme populations of Wolf-Rayet (WR) stars, the hot exposed cores of massive O stars, may be capable of powering CIII] at metallicities as high as a half-solar. If these moderately metal-poor extreme WR galaxies are indeed a viable source of strong CIII] emission, our interpretation of CIII] detections in the reionization era will be dramatically altered; but we presently have sufficient UV coverage for only three examples. Here, we propose HST/COS G160M and G185M observations of an additional seven extreme WR galaxies spanning 0.5 dex in metallicity around half-solar. These observations will constrain the maximum CIII] equivalent width these galaxies can power as a function of metallicity. The moderate resolution gratings will robustly characterize the massive O and WR star populations, allowing us to link the nebular emission directly to the massive stars responsible. These data will provide a stringent test for the population synthesis codes which will be applied to JWST observations. Without this empirical baseline, our understanding of the most distant galaxies JWST finds will be severely limited.

Finding the optical axis of a distant object using an optical alignment system based on a holographic marker

NASA Astrophysics Data System (ADS)

Zhuk, D. I.; Denisyuk, I. Yu.; Gutner, I. E.

2015-07-01

A way to construct a holographic indicator of the position of the central axis of a distant object based on recording a transmission hologram in a layer of photosensitive material and forming a remote real image before a light source is considered. A light source with a holographically formed marker designed for visual guidance to the object axis; it can be used to simplify aircraft landing on a glide path, preliminary visual alignment of large coaxial details of various machines, etc. Specific features of the scheme of recording a holographic marker and the reconstruction of its image are considered. The possibility of forming a remote holographic image marker, which can be aligned with a simultaneously operating reference laser system for determining the direction to an object and its optical axis, has been demonstrated experimentally.

Mach's Principle to Hubble's Law and Light Relativity

NASA Astrophysics Data System (ADS)

Zhang, Tianxi

2018-01-01

Discovery of the redshift-distance relation to be linear (i.e. Hubble's law) for galaxies in the end of 1920s instigated us to widely accept expansion of the universe, originated from a big bang around 14 billion years ago. Finding of the redshift-distance relation to be weaker than linear for distant type Ia supernovae nearly two decades ago further precipitated us to largely agree with recent acceleration of the universe, driven by the mysterious dark energy. The time dilation measured for supernovae has been claimed as a direct evidence for the expansion of the universe, but scientists could not explain why quasars and gamma-ray bursts had not similar time dilations. Recently, an anomaly was found in the standard template for the width of supernova light curves to be proportional to the wavelength, which exactly removed the time dilation of supernovae and hence was strongly inconsistent with the conventional redshift mechanism. In this study, we have derived a new redshift-distance relation from Mach's principle with light relativity that describes the effect of light on spacetime as well as the influence of disturbed spacetime on the light inertia or frequency. A moving object or photon, because of its continuously keeping on displacement, disturbs the rest of the entire universe or distorts/curves the spacetime. The distorted or curved spacetime then generates an effective gravitational force to act back on the moving object or photon, so that reduces the object inertia or photon frequency. Considering the disturbance of spacetime by a photon is extremely weak, we have modelled the effective gravitational force to be Newtonian and derived the new redshift-distance relation that can not only perfectly explain the redshift-distance measurement of distant type Ia supernovae but also inherently obtain Hubble's law as an approximate at small redshift. Therefore, the result obtained from this study does neither support the acceleration of the universe nor the expansion of the universe but prefers to Einstein's simplest cosmology of the static universe or Zhang's static or dynamic cosmology of the black hole universe. This work was partially supported by NSF/REU (Grant #: PHY-1559870) at Alabama A & M University

OBSERVATIONS OF MOLECULAR OUTFLOW IN CAR 291.6-01.9

DOE Office of Scientific and Technical Information (OSTI.GOV)

Saul, M.; Saul, L., E-mail: msaul@phys.unsw.edu.au, E-mail: luke.saul@space.unibe.ch

We report the first observations of a dense molecular gas nebula and bipolar outflow in Car 291.6-01.9, showing characteristics of an embedded young stellar object (YSO). Using the Mopra radio telescope near Coonabarabaran, Australia, we image the kinematic structure of several emission features to examine physical properties within a molecular clump of mass {approx}3.2 {+-} 0.6 Multiplication-Sign 10{sup 3} M{sub Sun} in which a stellar cluster may be forming. Motivated by acquiring a more thorough understanding of star formation we ask what may have initiated collapse in the clump; observed outflow alignment is suggestive of {approx}1.0 pc distant massive starmore » HD 308280 radiative-driven compression as a formation trigger for the dense core. An outflow derived age of <10{sup 6} years, together with significant C{sup 18}O and SO core depletion, support the case for the core as the host of an extremely YSO cluster.« less

IRAS 14348-1447, an ultraluminous pair of colliding, gas-rich galaxies - The birth of a quasar?

NASA Technical Reports Server (NTRS)

Sanders, D. B.; Soifer, B. T.; Scoville, N. Z.

1988-01-01

Ground-baed observations of the object IRAS 14348-1447, which was discovered with the Infrared Astronomical Satellite, show that it is an extremely luminous colliding galaxy system that emits more than 95 percent of its energy at FIR wavelengths. IRAS 14348-1447, which is receeding from the sun at 8 percent of the speed of light, has a bolometric luminosity more than 100 times larger than that of the Galaxy, and is therefore as luminous as optical quasars. New optical, infrared, and spectroscopic measurements suggest that the dominant luminosity source is a dust-enshrouded quasar. The fuel for the intense activity is an enormous supply of molecular gas. Carbon monoxide emission has been detected at a wavelength of 2.6 millimeters by means of a new, more sensitive receiver recently installed on the 12-meter telescope of the National Radio Astronomy Observatory. IRAS 14348-1447 is the most distant and luminous source of carbon monoxide line emission yet detected.

A VLT Large Programme to Study Galaxies at z ~ 2: GMASS — the Galaxy Mass Assembly Ultra-deep Spectroscopic Survey

NASA Astrophysics Data System (ADS)

Kurk, Jaron; Cimatti, Andrea; Daddi, Emanuele; Mignoli, Marco; Bolzonella, Micol; Pozzetti, Lucia; Cassata, Paolo; Halliday, Claire; Zamorani, Gianni; Berta, Stefano; Brusa, Marcella; Dickinson, Mark; Franceschini, Alberto; Rodighiero, Guilia; Rosati, Piero; Renzini, Alvio

2009-03-01

We report on the motivation, sample selection and first results of our VLT FORS2 Large Programme (173.A-0687), which has obtained the longest targeted spectra of distant galaxies obtained so far with the VLT. These long exposures, up to 77 hours for objects included in three masks, were required to detect spectral features of extremely faint galaxies, such as absorption lines of passive galaxies at z > 1.4, a population that had previously escaped attention due to its faintness in the optical wavelength regime, but which represents a critical phase in the evolution of massive galaxies. The ultra-deep spectroscopy allowed us to estimate the stellar metallicity of star-forming galaxies at z ~ 2, to trace colour bimodality up to z = 2 and to characterise a galaxy cluster progenitor at z = 1.6. The approximately 200 spectra produced by GMASS constitute a lasting legacy, populating the “redshift desert” in GOODS-S.

The Cosmic Dance of Distant Galaxies

NASA Astrophysics Data System (ADS)

2006-03-01

GIRAFFE at VLT reveals the turbulent life of distant galaxies Studying several tens of distant galaxies, an international team of astronomers found that galaxies had the same amount of dark matter relative to stars 6 billion years ago as they have now. If confirmed, this suggests a much closer interplay between dark and normal matter than previously believed. The scientists also found that as many as 4 out of 10 galaxies are out of balance. These results shed a new light on how galaxies form and evolve since the Universe was only half its current age. ESO PR Photo 10a/06 ESO PR Photo 10a/06 Collision Between Galaxies (Artist's Impression) "This may imply that collisions and merging are important in the formation and evolution of galaxies", said François Hammer, Paris Observatory, France, and one of the leaders of the team [1]. The scientists were interested in finding out how galaxies that are far away - thus seen as they were when the Universe was younger - evolved into the ones nearby. In particular, they wanted to study the importance of dark matter in galaxies. "Dark matter, which composes about 25% of the Universe, is a simple word to describe something we really don't understand," said Hector Flores, co-leader. "From looking at how galaxies rotate, we know that dark matter must be present, as otherwise these gigantic structures would just dissolve." In nearby galaxies, and in our own Milky Way for that matter, astronomers have found that there exists a relation between the amount of dark matter and ordinary stars: for every kilogram of material within a star there is roughly 30 kilograms of dark matter. But does this relation between dark and ordinary matter still hold in the Universe's past? ESO PR Photo 10b/06 ESO PR Photo 10b/06 Mapping Distant Galaxies (FLAMES-GIRAFFE/VLT) This required measuring the velocity in different parts of distant galaxies, a rather tricky experiment: previous measurements were indeed unable to probe these galaxies in sufficient detail, since they had to select a single slit, i.e. a single direction, across the galaxy. Things changed with the availability of the multi-object GIRAFFE spectrograph [2], now installed on the 8.2-m Kueyen Unit Telescope of ESO's Very Large Telescope (VLT) at the Paranal Observatory (Chile). In one mode, known as "3-D spectroscopy" or "integral field", this instrument can obtain simultaneous spectra of smaller areas of extended objects like galaxies or nebulae. For this, 15 deployable fibre bundles, the so-called Integral Field Units (IFUs) , cf. ESO PR 01/02 , are used to make meticulous measurements of distant galaxies. Each IFU is a microscopic, state-of-the-art two-dimensional lens array with an aperture of 3 x 2 arcsec2 on the sky. It is like an insect's eye, with twenty micro-lenses coupled with optical fibres leading the light recorded at each point in the field to the entry slit of the spectrograph. ESO PR Photo 10c/06 ESO PR Photo 10c/06 Dark Matter and Stellar Mass in Distant Galaxies "GIRAFFE on ESO's VLT is the only instrument in the world that is able to analyze simultaneously the light coming from 15 galaxies covering a field of view almost as large as the full moon," said Mathieu Puech, lead author of one the papers presenting the results [3]. "Every galaxy observed in this mode is split into continuous smaller areas where spectra are obtained at the same time." The astronomers used GIRAFFE to measure the velocity fields of several tens of distant galaxies, leading to the surprising discovery that as much as 40% of distant galaxies were "out of balance" - their internal motions were very disturbed - a possible sign that they are still showing the aftermath of collisions between galaxies. When they limited themselves to only those galaxies that have apparently reached their equilibrium, the scientists found that the relation between the dark matter and the stellar content did not appear to have evolved during the last 6 billions years. Thanks to its exquisite spectral resolution, GIRAFFE also allows for the first time to study the distribution of gas as a function of its density in such distant galaxies. The most spectacular results reveal a possible outflow of gas and energy driven by the intense star-formation within the galaxy and a giant region of very hot gas (HII region) in a galaxy in equilibrium that produces many stars. "Such a technique can be expanded to obtain maps of many physical and chemical characteristics of distant galaxies, enabling us to study in detail how they assembled their mass during their entire life," said François Hammer. "In many respects, GIRAFFE and its multi-integral field mode gives us a first flavour of what will be achieved with future extremely large telescopes." Notes [1]: The team comprises: François Hammer, Hector Flores, Mathieu Puech, Chantal Balkowski (GEPI - Observatoire de Paris), Philippe Amram (LAM - Observatoire Astronomique Marseille-Provence), Göran Östlin (Stockholm Observatory), Thomas Marquart (Dept. of Astronomy and Space Physics - Uppsala, Sweden) and Matthew D. Lehnert (MPE, Germany). [2]: This complex and unique instrument allows obtaining high-quality spectra of a large variety of celestial objects, from individual stars in the Milky Way and other nearby galaxies, to very distant galaxies. It functions by means of multiple optical fibres that guide the light from the telescope's focal plane into the entry slit of the spectrograph. Here the light is dispersed into its different colours. GIRAFFE and these fibres are an integral part of the advanced Fibre Large Array Multi-Element Spectrograph (FLAMES) facility which also includes the OzPoz positioner and an optical field corrector. It is the outcome of a collaboration between ESO, Observatoire de Paris-Meudon, Observatoire de Genève-Lausanne and the Anglo Australian Observatory (AAO). More details are available in ESO PR 01/02. The principle of this instrument involves the positioning in the telescope's focal plane of a large number of optical fibres. This is done in such a way that each of them guides the light from one particular celestial object towards the spectrograph that records the spectra of all these objects simultaneously. The size of the available field-of-view is no less than about 25 arcmin across, i.e. almost as large as the full moon. The individual fibres are moved and positioned "on the objects" in the field by means of the OzPoz positioner. See also ESO PR 13/02. [3]: The results will be published in a series of three papers in the leading research journal, Astronomy and Astrophysics (click on the title to access the papers): "3D spectroscopy with VLT/GIRAFFE - I: The true Tully-Fisher relationship at z~ 0.6" (Flores H., Hammer F., Puech M. et al.); "3D spectroscopy with VLT/GIRAFFE - II: Are Luminous Compact Galaxies merger remnants?" (Puech M., Hammer F., Flores H. et al.); and "3D spectroscopy with VLT/GIRAFFE - III: Mapping electron densities in distant galaxies" (Puech M., Flores H., Hammer F. & Lehnert M.D.).

Overt Skeletal Metastases in a Patient of Occult (Microscopic) Follicular Thyroid Carcinoma: a Rare Case.

PubMed

Jha, Chandan Kumar; Agrawal, Vinita; Mishra, Anjali; Pradhan, P K

2018-03-01

Occult follicular thyroid carcinoma (FTC) presenting as distant metastases is a rare occurrence. However, despite being occult in majority of these cases, primary tumor can be detected on thyroid imaging or during surgery. Here, we present an extremely rare case of an occult FTC with overt skeletal metastases in which primary tumor was discernible only on microscopic examination.

A Multifactorial Analysis of Melanoma: Prognostic Histopathological Features Comparing Clark's and Breslow's Staging Methods

PubMed Central

Balch, Charles M.; Murad, Tariq M.; Soong, Seng-Jaw; Ingalls, Anna Lee; Halpern, Norman B.; Maddox, William A.

1978-01-01

A multifactorial analysis was used to identify the dominant prognostic variables affecting survival from a computerized data base of 339 melanoma patients treated at this institution during the past 17 years. Five of the 13 parameters examined simultaneously were found to independently influence five year survival rates: 1) pathological stage (I vs II, p = 0.0014), 2) lesion ulceration (present vs absent, p = 0.006), 3) surgical treatment (wide excision vs wide excision plus lymphadenectomy, p = 0.024), 4) melanoma thickness (p = 0.032), and 5) location (upper extremity vs lower extremity vs trunk vs head and neck, p = 0.038). Additional factors considered that had either indirect or no influence on survival rates were clinical stage of disease, age, sex, level of invasion, pigmentation, lymphocyte infiltration, growth pattern, and regression. Most of these latter variables derived their prognostic value from correlation with melanoma thickness, except sex which correlated with location (extremity lesions were more frequent on females, trunk lesions on males). This statistical analysis enabled us to derive a mathematical equation for predicting an individual patient's probability of five year survival. Three categories of risk were delineated by measuring tumor thickness (Breslow microstaging) in Stage I patients: 1) thin melanomas (<0.76 mm) were associated with localized disease and a 100% cure rate: 2) intermediate thickness melanomas (0.76-4.00 mm) had an increasing risk (up to 80%) of harboring regional and/or distant metastases and 3) thick melanomas (≥4.00 mm) had a 80% risk of occult distant metastases at the time of initial presentation. The level of invasion (Clark's microstaging) correlated with survival, but was less predictive than measuring tumor thickness. Within each of Clark's Level II, III and IV groups, there were gradations of thickness with statistically different survival rates. Both microstaging methods (Breslow and Clark) were less predictive factors in patients with lymph node or distant metastases. Clinical trials evaluating alternative surgical treatments or adjunctive therapy modalities for melanoma patients should incorporate these parameters into their assessment, especially in Stage I (localized) disease where tumor thickness and the anatomical site of the primary melanoma are dominant prognostic factors. PMID:736651

On Using Intensity Interferometry for Feature Identification and Imaging of Remote Objects

NASA Technical Reports Server (NTRS)

Erkmen, Baris I.; Strekalov, Dmitry V.; Yu, Nan

2013-01-01

We derive an approximation to the intensity covariance function of two scanning pinhole detectors, facing a distant source (e.g., a star) being occluded partially by an absorptive object (e.g., a planet). We focus on using this technique to identify or image an object that is in the line-of-sight between a well-characterized source and the detectors. We derive the observed perturbation to the intensity covariance map due to the object, showing that under some reasonable approximations it is proportional to the real part of the Fourier transform of the source's photon-flux density times the Fourier transform of the object's intensity absorption. We highlight the key parameters impacting its visibility and discuss the requirements for estimating object-related parameters, e.g., its size, velocity or shape. We consider an application of this result to determining the orbit inclination of an exoplanet orbiting a distant star. Finally, motivated by the intrinsically weak nature of the signature, we study its signal-to-noise ratio and determine the impact of system parameters.

A search for N-type galaxies

NASA Technical Reports Server (NTRS)

Jefferies, J. T.

1971-01-01

A large number of distant clusters of galaxies was examined for the presence of a bright compact galaxy or blue stellar object. Nearly 600 square degrees of sky were searched using glass copies of the National Geographic Society-Palomar Observatory Sky Survey plates, and over 20 fields were selected for observation. The objects were examined for infrared and ultraviolet excesses, using wideband filter photography and spectroscopy. Initial findings include a faint, distant cluster of galaxies near the quasi-stellar radio source 4C 37.43 with a red shift of 0.370. One of these galaxies has an emission line at 6895 A, indicating a possible red shift of 0.377 of the 5007 A line of (0 III).

Evidence for a New Class of Extreme Ultraviolet Sources

NASA Technical Reports Server (NTRS)

Maoz, Dan; Ofek, Eran O.; Shemi, Amotz

1997-01-01

Most of the sources detected in the extreme ultraviolet (EUV; 100-600 A) by the ROSAT/WFC and EUVE all-sky surveys have been identified with active late-type stars and hot white dwarfs that are near enough to the Earth to escape absorption by interstellar gas. However, about 15 per cent of EUV sources are as yet unidentified with any optical counterparts. We examine whether the unidentified EUV sources may consist of the same population of late-type stars and white dwarfs. We present B and R photometry of stars in the fields of seven of the unidentified EUV sources. We detect in the optical the entire main-sequence and white dwarf population out to the greatest distances where they could still avoid absorption. We use color-magnitude diagrams to demonstrate that, in most of the fields, none of the observed stars has the colours and magnitudes of late-type dwarfs at distances less than 100 pc. Similarly, none of the observed stars is a white dwarf within 500 pc that is hot enough to be a EUV emitter. The unidentified EUV sources we study are not detected in X-rays, while cataclysmic variables, X-ray binaries, and active galactic nuclei generally are. We conclude that some of the EUV sources may be a new class of nearby objects, which are either very faint at optical bands or which mimic the colours and magnitudes of distant late-type stars or cool white dwarfs. One candidate for optically faint objects is isolated old neutron stars, slowly accreting interstellar matter. Such neutron stars are expected to be abundant in the Galaxy, and have not been unambiguously detected.

The Observatory for Multi-Epoch Gravitational Lens Astrophysics (OMEGA)

NASA Astrophysics Data System (ADS)

Moustakas, Leonidas A.; Bolton, Adam J.; Booth, Jeffrey T.; Bullock, James S.; Cheng, Edward; Coe, Dan; Fassnacht, Christopher D.; Gorjian, Varoujan; Heneghan, Cate; Keeton, Charles R.; Kochanek, Christopher S.; Lawrence, Charles R.; Marshall, Philip J.; Metcalf, R. Benton; Natarajan, Priyamvada; Nikzad, Shouleh; Peterson, Bradley M.; Wambsganss, Joachim

2008-07-01

Dark matter in a universe dominated by a cosmological constant seeds the formation of structure and is the scaffolding for galaxy formation. The nature of dark matter remains one of the fundamental unsolved problems in astrophysics and physics even though it represents 85% of the mass in the universe, and nearly one quarter of its total mass-energy budget. The mass function of dark matter "substructure" on sub-galactic scales may be enormously sensitive to the mass and properties of the dark matter particle. On astrophysical scales, especially at cosmological distances, dark matter substructure may only be detected through its gravitational influence on light from distant varying sources. Specifically, these are largely active galactic nuclei (AGN), which are accreting super-massive black holes in the centers of galaxies, some of the most extreme objects ever found. With enough measurements of the flux from AGN at different wavelengths, and their variability over time, the detailed structure around AGN, and even the mass of the super-massive black hole can be measured. The Observatory for Multi-Epoch Gravitational Lens Astrophysics (OMEGA) is a mission concept for a 1.5-m near-UV through near-IR space observatory that will be dedicated to frequent imaging and spectroscopic monitoring of ~100 multiply-imaged active galactic nuclei over the whole sky. Using wavelength-tailored dichroics with extremely high transmittance, efficient imaging in six channels will be done simultaneously during each visit to each target. The separate spectroscopic mode, engaged through a flip-in mirror, uses an image slicer spectrograph. After a period of many visits to all targets, the resulting multidimensional movies can then be analyzed to a) measure the mass function of dark matter substructure; b) measure precise masses of the accreting black holes as well as the structure of their accretion disks and their environments over several decades of physical scale; and c) measure a combination of Hubble's local expansion constant and cosmological distances to unprecedented precision. We present the novel OMEGA instrumentation suite, and how its integrated design is ideal for opening the time domain of known cosmologically-distant variable sources, to achieve the stated scientific goals.

Unveiling the extreme nature of the hyper faint galaxy Virgo I

NASA Astrophysics Data System (ADS)

Crnojevic, Denija

2017-08-01

We request HST/ACS imaging to obtain a deep color-magnitude diagram of the newly discovered candidate Milky Way satellite Virgo I. With an estimated absolute magnitude of only M_V -0.8 and a Galactocentric radius of 90 kpc, Virgo I is one of the faintest and most distant dwarfs ever observed, and could be identified as a prototype ''hyper'' faint galaxy. The detailed characterization of the smallest inhabited dark matter subhalos is crucial to guide hierarchical galaxy formation models, and in particular to constrain reionization, the nature of the dark matter particle, etc. With the advent of deep wide-field, ground-based surveys, the potential of uncovering these lowest-mass galaxies is quickly turning into reality, as demonstrated by the discovery in the past two years of tens of new Local Group members in the ultra-faint regime (M_V>-8). Virgo I represents a new record in galaxy physical properties, and urges us to be prepared for the likely emergence of an entirely new class of such objects in the era of future wide-field surveys (e.g., LSST). Only high resolution HST observations can enable us to confirm the nature of Virgo I, providing significantly more accurate estimates for its distance and structural properties, when compared to the discovery Subaru/HyperSuprimeCam imaging. Our proposed dataset will constitute a fundamental step in the upcoming hunt for galaxies with similarly extreme properties.

Estimating sizes of faint, distant galaxies in the submillimetre regime

NASA Astrophysics Data System (ADS)

Lindroos, L.; Knudsen, K. K.; Fan, L.; Conway, J.; Coppin, K.; Decarli, R.; Drouart, G.; Hodge, J. A.; Karim, A.; Simpson, J. M.; Wardlow, J.

2016-10-01

We measure the sizes of redshift ˜2 star-forming galaxies by stacking data from the Atacama Large Millimeter/submillimeter Array (ALMA). We use a uv-stacking algorithm in combination with model fitting in the uv-domain and show that this allows for robust measures of the sizes of marginally resolved sources. The analysis is primarily based on the 344 GHz ALMA continuum observations centred on 88 submillimetre galaxies in the LABOCA ECDFS Submillimeter Survey (ALESS). We study several samples of galaxies at z ≈ 2 with M* ≈ 5 × 1010 M⊙, selected using near-infrared photometry (distant red galaxies, extremely red objects, sBzK-galaxies, and galaxies selected on photometric redshift). We find that the typical sizes of these galaxies are ˜0.6 arcsec which corresponds to ˜5 kpc at z = 2, this agrees well with the median sizes measured in the near-infrared z band (˜0.6 arcsec). We find errors on our size estimates of ˜0.1-0.2 arcsec, which agree well with the expected errors for model fitting at the given signal-to-noise ratio. With the uv-coverage of our observations (18-160 m), the size and flux density measurements are sensitive to scales out to 2 arcsec. We compare this to a simulated ALMA Cycle 3 data set with intermediate length baseline coverage, and we find that, using only these baselines, the measured stacked flux density would be an order of magnitude fainter. This highlights the importance of short baselines to recover the full flux density of high-redshift galaxies.

Community analysis of hydrogen-producing extreme thermophilic anaerobic microflora enriched from cow manure with five substrates.

PubMed

Yokoyama, Hiroshi; Moriya, Naoko; Ohmori, Hideyuki; Waki, Miyoko; Ogino, Akifumi; Tanaka, Yasuo

2007-11-01

The present study analyzed the community structures of anaerobic microflora producing hydrogen under extreme thermophilic conditions by two culture-independent methods: denaturing gradient gel electrophoresis (DGGE) and clone library analyses. Extreme thermophilic microflora (ETM) was enriched from cow manure by repeated batch cultures at 75 degrees C, using a substrate of xylose, glucose, lactose, cellobiose, or soluble starch, and produced hydrogen at yields of 0.56, 2.65, 2.17, 2.68, and 1.73 mol/mol-monosaccharide degraded, respectively. The results from the DGGE and clone library analyses were consistent and demonstrated that the community structures of ETM enriched with the four hexose-based substrates (glucose, lactose, cellobiose, and soluble starch) consisted of a single species, closely related to a hydrogen-producing extreme thermophile, Caldoanaerobacter subterraneus, with diversity at subspecies levels. The ETM enriched with xylose was more diverse than those enriched with the other substrates, and contained the bacterium related to C. subterraneus and an unclassified bacterium, distantly related to a xylan-degrading and hydrogen-producing extreme thermophile, Caloramator fervidus.

Measuring Distances to Remote Galaxies and Quasars.

ERIC Educational Resources Information Center

McCarthy, Patrick J.

1988-01-01

Describes the use of spectroscopy and the redshift to measure how far an object is by measuring how fast it is receding from earth. Lists the most distant quasars yet found. Tables include "Redshift vs. Distance" and "Distances to Celestial Objects for Various Cosmologies." (CW)

Debiasing the Distant Solar System Populations Using Pan-STARRS1

NASA Astrophysics Data System (ADS)

Lilly Schunova, Eva; Weryk, Robert J.; Chastel, Serge; Denneau, Larry; Jedicke, Robert; Wainscoat, Richard J.; Chambers, Kenneth C.

2017-10-01

We discuss our on-going effort to identify Trans-Neptunian Objects (TNOs) in the Pan-STARRS1 dataset, and to debias the size-frequency distributions (SFD) of detected TNO sub-populations in order to estimate their true population sizes. To measure our detection efficiency we used the model of Grav et al. (2011)[1], which includes Kuiper belt Objects (KBOs), Scattered Disc Objects (SDOs), and Centaurs. Our debiasing method accounts for the per-chip CCD sensitivity as well as CCD cell gaps. The search method for finding distant Solar System objects, which was developed for our initial work (Weryk et al., 2016)[2], led to discovery of 29 Centaurs, 243 KBOs and 61 SDOs from Pan-STARRS data spanning years 2010-2015. Our work is extended using more recent PS1 data.[1] Grav, T., et al. (2011), Publications of the Astronomical Society of Pacific, Volume 123, Issue 902, pp. 423.[2] Weryk, R.J., et al. (2016), eprint arXiv:1607.04895.

The Generation of the Distant Kuiper Belt by Planet Nine from an Initially Broad Perihelion Distribution

NASA Astrophysics Data System (ADS)

Khain, Tali; Batygin, Konstantin; Brown, Michael E.

2018-04-01

The observation that the orbits of long-period Kuiper Belt objects are anomalously clustered in physical space has recently prompted the Planet Nine hypothesis - the proposed existence of a distant and eccentric planetary member of our Solar System. Within the framework of this model, a Neptune-like perturber sculpts the orbital distribution of distant Kuiper Belt objects through a complex interplay of resonant and secular effects, such that the surviving orbits get organized into apsidally aligned and anti-aligned configurations with respect to Planet Nine's orbit. We present results on the role of Kuiper Belt initial conditions on the evolution of the outer Solar System using numerical simulations. Intriguingly, we find that the final perihelion distance distribution depends strongly on the primordial state of the system, and demonstrate that a bimodal structure corresponding to the existence of both aligned and anti-aligned clusters is only reproduced if the initial perihelion distribution is assumed to extend well beyond 36 AU. The bimodality in the final perihelion distance distribution is due to the permanently stable objects, with the lower perihelion peak corresponding to the anti-aligned orbits and the higher perihelion peak corresponding to the aligned orbits. We identify the mechanisms that enable the persistent stability of these objects and locate the regions of phase space in which they reside. The obtained results contextualize the Planet Nine hypothesis within the broader narrative of solar system formation, and offer further insight into the observational search for Planet Nine.

Paraganglioma with intracranial metastasis: a case report and review of the literature.

PubMed

Cai, Peihao; Mahta, Ali; Kim, Ryan Y; Kesari, Santosh

2012-10-01

Paragangliomas are rare neuroendocrine tumors of neural crest origin. They are mostly benign, however; malignant tumors with aggressive behavior and distant metastasis can also occur. Intracranial involvement is extremely rare and has been sporadically reported in the literature. Here we report a case who presented with progressive neurologic deficits due to multiple intracranial lesions found to be metastasis from an occult retroperitoneal malignant paraganglioma.

Foggy perception slows us down.

PubMed

Pretto, Paolo; Bresciani, Jean-Pierre; Rainer, Gregor; Bülthoff, Heinrich H

2012-10-30

Visual speed is believed to be underestimated at low contrast, which has been proposed as an explanation of excessive driving speed in fog. Combining psychophysics measurements and driving simulation, we confirm that speed is underestimated when contrast is reduced uniformly for all objects of the visual scene independently of their distance from the viewer. However, we show that when contrast is reduced more for distant objects, as is the case in real fog, visual speed is actually overestimated, prompting drivers to decelerate. Using an artificial anti-fog-that is, fog characterized by better visibility for distant than for close objects, we demonstrate for the first time that perceived speed depends on the spatial distribution of contrast over the visual scene rather than the global level of contrast per se. Our results cast new light on how reduced visibility conditions affect perceived speed, providing important insight into the human visual system.DOI:http://dx.doi.org/10.7554/eLife.00031.001.

Chandra Finds Most Distant X-ray Galaxy Cluster

NASA Astrophysics Data System (ADS)

2001-02-01

The most distant X-ray cluster of galaxies yet has been found by astronomers using NASA’s Chandra X-ray Observatory. Approximately 10 billion light years from Earth, the cluster 3C294 is 40 percent farther than the next most distant X-ray galaxy cluster. The existence of such a distant galaxy cluster is important for understanding how the universe evolved. "Distant objects like 3C294 provide snapshots to how these galaxy clusters looked billions of years ago," said Andrew Fabian of the Institute of Astronomy, Cambridge, England and lead author of the paper accepted for publication in the Monthly Notices of Britain’s Royal Astronomical Society. "These latest results help us better understand what the universe was like when it was only 20 percent of its current age." Chandra’s image reveals an hourglass-shaped region of X-ray emission centered on the previously known central radio source. This X-ray emission extends outward from the central galaxy for at least 300,000 light years and shows that the known radio source is in the central galaxy of a massive cluster. Scientists have long suspected that distant radio-emitting galaxies like 3C294 are part of larger groups of galaxies known as "clusters." However, radio data provides astronomers with only a partial picture of these distant objects. Confirmation of the existence of clusters at great distances - and, hence, at early stages of the universe - requires information from other wavelengths. Optical observations can be used to pinpoint individual galaxies, but X-ray data are needed to detect the hot gas that fills the space within the cluster. "Galaxy clusters are the largest gravitationally bound structures in the universe," said Fabian. "We do not expect to find many massive objects, such as the 3C294 cluster, in early times because structure is thought to grow from small scales to large scales." The vast clouds of hot gas that envelope galaxies in clusters are thought to be heated by collapse toward the center of the cluster. Until Chandra, X-ray telescopes have not had the needed sensitivity to identify and measure hot gas clouds in distant clusters. Carolin Crawford, Stefano Ettori and Jeremy Sanders of the Institute of Astronomy were also members of the team that observed 3C294 for 5.4 hours on October 29, 2000 with the Advanced CCD Imaging Spectrometer (ACIS). The ACIS X-ray camera was developed for NASA by Pennsylvania State University and Massachusetts Institute of Technology. NASA's Marshall Space Flight Center in Huntsville, AL, manages the Chandra program for the Office of Space Science in Washington, DC. The Smithsonian's Chandra X-ray Center controls science and flight operations from Cambridge, MA. Images associated with this release are available on the World Wide Web at: http://chandra.harvard.edu AND http://chandra.nasa.gov

How do probiotics and prebiotics function at distant sites?

PubMed

Reid, G; Abrahamsson, T; Bailey, M; Bindels, L B; Bubnov, R; Ganguli, K; Martoni, C; O'Neill, C; Savignac, H M; Stanton, C; Ship, N; Surette, M; Tuohy, K; van Hemert, S

2017-08-24

The realisation that microbes regarded as beneficial to the host can impart effects at sites distant from their habitat, has raised many possibilities for treatment of diseases. The objective of a workshop hosted in Turku, Finland, by the International Scientific Association for Probiotics and Prebiotics, was to assess the evidence for these effects and the extent to which early life microbiome programming influences how the gut microbiota communicates with distant sites. In addition, we examined how probiotics and prebiotics might affect the skin, airways, heart, brain and metabolism. The growing levels of scientific and clinical evidence showing how microbes influence the physiology of many body sites, leads us to call for more funding to advance a potentially exciting avenue for novel therapies for many chronic diseases.

Very-high-energy gamma rays from a distant quasar: how transparent is the universe?

PubMed

Albert, J; Aliu, E; Anderhub, H; Antonelli, L A; Antoranz, P; Backes, M; Baixeras, C; Barrio, J A; Bartko, H; Bastieri, D; Becker, J K; Bednarek, W; Berger, K; Bernardini, E; Bigongiari, C; Biland, A; Bock, R K; Bonnoli, G; Bordas, P; Bosch-Ramon, V; Bretz, T; Britvitch, I; Camara, M; Carmona, E; Chilingarian, A; Commichau, S; Contreras, J L; Cortina, J; Costado, M T; Covino, S; Curtef, V; Dazzi, F; De Angelis, A; De Cea Del Pozo, E; de Los Reyes, R; De Lotto, B; De Maria, M; De Sabata, F; Mendez, C Delgado; Dominguez, A; Dorner, D; Doro, M; Errando, M; Fagiolini, M; Ferenc, D; Fernández, E; Firpo, R; Fonseca, M V; Font, L; Galante, N; López, R J García; Garczarczyk, M; Gaug, M; Goebel, F; Hayashida, M; Herrero, A; Höhne, D; Hose, J; Hsu, C C; Huber, S; Jogler, T; Kneiske, T M; Kranich, D; La Barbera, A; Laille, A; Leonardo, E; Lindfors, E; Lombardi, S; Longo, F; López, M; Lorenz, E; Majumdar, P; Maneva, G; Mankuzhiyil, N; Mannheim, K; Maraschi, L; Mariotti, M; Martínez, M; Mazin, D; Meucci, M; Meyer, M; Miranda, J M; Mirzoyan, R; Mizobuchi, S; Moles, M; Moralejo, A; Nieto, D; Nilsson, K; Ninkovic, J; Otte, N; Oya, I; Panniello, M; Paoletti, R; Paredes, J M; Pasanen, M; Pascoli, D; Pauss, F; Pegna, R G; Perez-Torres, M A; Persic, M; Peruzzo, L; Piccioli, A; Prada, F; Prandini, E; Puchades, N; Raymers, A; Rhode, W; Ribó, M; Rico, J; Rissi, M; Robert, A; Rügamer, S; Saggion, A; Saito, T Y; Salvati, M; Sanchez-Conde, M; Sartori, P; Satalecka, K; Scalzotto, V; Scapin, V; Schmitt, R; Schweizer, T; Shayduk, M; Shinozaki, K; Shore, S N; Sidro, N; Sierpowska-Bartosik, A; Sillanpää, A; Sobczynska, D; Spanier, F; Stamerra, A; Stark, L S; Takalo, L; Tavecchio, F; Temnikov, P; Tescaro, D; Teshima, M; Tluczykont, M; Torres, D F; Turini, N; Vankov, H; Venturini, A; Vitale, V; Wagner, R M; Wittek, W; Zabalza, V; Zandanel, F; Zanin, R; Zapatero, J

2008-06-27

The atmospheric Cherenkov gamma-ray telescope MAGIC, designed for a low-energy threshold, has detected very-high-energy gamma rays from a giant flare of the distant Quasi-Stellar Radio Source (in short: radio quasar) 3C 279, at a distance of more than 5 billion light-years (a redshift of 0.536). No quasar has been observed previously in very-high-energy gamma radiation, and this is also the most distant object detected emitting gamma rays above 50 gigaelectron volts. Because high-energy gamma rays may be stopped by interacting with the diffuse background light in the universe, the observations by MAGIC imply a low amount for such light, consistent with that known from galaxy counts.

Pioneer 11 encounter: preliminary results from the ames research center plasma analyzer experiment.

PubMed

Mihaloy, J D; Collard, H R; McKibbin, D D; Wolfe, J H; Intriligator, D S

1975-05-02

Pioneer 11 observations of the interaction of Jupiter's magnetosphere with the distant solar wind have confirmed the earlier Pioneer 10 observations of the great size and extreme variability of the outer magnetosphere. The nature of the plasma transitions across Jupiter's bow shock and magnetopause as observed on Pioneer 10 have also been confirmed on Pioneer 11. However, the northward direction of the Pioneer 11 outbound trajectory and the distance of the final magnetopause crossing (80 Jupiter radii) now suggest that Jupiter's magnetosphere is extremely broad with a half-thickness (normal to the ecliptic plane in the noon meridian) which is comparable to or greater than the sunward distance to the nose.

Clear cell hidradenocarcinoma of the breast: a very rare breast skin tumor.

PubMed

Mezzabotta, Maurizio; Declich, Paolo; Cardarelli, Mery; Bellone, Stefano; Pacilli, Paolo; Riggio, Eliana; Pallino, Antonio

2012-01-01

Hidradenocarcinoma is an uncommon malignant intradermal tumor of sweat gland origin with a predilection for the face and extremities. It is encountered equally in males and females, usually in the second half of life. These tumors tend to be locally aggressive. In our case, the tumor was located relatively superficially but without any apparent connection to the overlying skin. The typical disease course includes local and sometimes multiple recurrences, and some patients develop regional lymph node and distant metastases. These type of tumors in the parenchyma of the breast are extremely rare. We report a case of hidradenocarcinoma in a 77-year-old woman who presented with a palpable inflammatory nodule in the right breast.

Lunar Observatories: Why, Where, and When?

NASA Technical Reports Server (NTRS)

Lowman, D. Paul, Jr.; Durst, Steve; Chen, Peter C.

1999-01-01

The value of Moon-based astronomical instruments has been repeatedly supported by several major studies and conferences, such as the "Astrophysics from the Moon" meeting held in Annapolis, Maryland, in 1990 (Mumma and Smith, 1990). A comprehensive review of the advantages of lunar observatories was published in the same year by Burns et al. (1990). However, the decade since then has seen a number of major developments bearing on the topic of lunar observatories, including the following. Two space astronomy programs have been outstandingly successful since 1990: the Cosmic Background Explorer ((COBE) and the Hubble Space Telescope (HST). These instruments have shown for the first time the structure of the universe in the first stages of its creation, i.e., the "Big Bang." One result of these discoveries has been to focus new space astronomy programs on fundamental problems such as shape of the universe, evolution of galaxies, and the nature of "dark" matter. Since these questions involve the very earliest stages of the history of the universe, to study them requires observation of extremely distant objects. Because of the expansion of the universe, all radiation from such objects is greatly redshifted, into the infrared region of the spectrum. For this reason, the Next Generation Space Telescope, the successor to HST, will be an infrared telescope.

Personalized Learning Objects Recommendation Based on the Semantic-Aware Discovery and the Learner Preference Pattern

ERIC Educational Resources Information Center

Wang, Tzone I; Tsai, Kun Hua; Lee, Ming Che; Chiu, Ti Kai

2007-01-01

With vigorous development of the Internet, especially the web page interaction technology, distant E-learning has become more and more realistic and popular. Digital courses may consist of many learning units or learning objects and, currently, many learning objects are created according to SCORM standard. It can be seen that, in the near future,…

Chaotic Dynamics of Trans-Neptunian Objects Perturbed by Planet Nine

NASA Astrophysics Data System (ADS)

Hadden, Sam; Li, Gongjie; Payne, Matthew J.; Holman, Matthew J.

2018-06-01

Observations of clustering among the orbits of the most distant trans-Neptunian objects (TNOs) has inspired interest in the possibility of an undiscovered ninth planet lurking in the outskirts of the solar system. Numerical simulations by a number of authors have demonstrated that, with appropriate choices of planet mass and orbit, such a planet can maintain clustering in the orbital elements of the population of distant TNOs, similar to the observed sample. However, many aspects of the rich underlying dynamical processes induced by such a distant eccentric perturber have not been fully explored. We report the results of our investigation of the dynamics of coplanar test-particles that interact with a massive body on an circular orbit (Neptune) and a massive body on a more distant, highly eccentric orbit (the putative Planet Nine). We find that a detailed examination of our idealized simulations affords tremendous insight into the rich test-particle dynamics that are possible. In particular, we find that chaos and resonance overlap plays an important role in particles’ dynamical evolution. We develop a simple mapping model that allows us to understand, in detail, the web of overlapped mean-motion resonances explored by chaotically evolving particles. We also demonstrate that gravitational interactions with Neptune can have profound effects on the orbital evolution of particles. Our results serve as a starting point for a better understanding of the dynamical behavior observed in more complicated simulations that can be used to constrain the mass and orbit of Planet Nine.

Galaxy Cluster Smashes Distance Record

NASA Astrophysics Data System (ADS)

2009-10-01

he most distant galaxy cluster yet has been discovered by combining data from NASA's Chandra X-ray Observatory and optical and infrared telescopes. The cluster is located about 10.2 billion light years away, and is observed as it was when the Universe was only about a quarter of its present age. The galaxy cluster, known as JKCS041, beats the previous record holder by about a billion light years. Galaxy clusters are the largest gravitationally bound objects in the Universe. Finding such a large structure at this very early epoch can reveal important information about how the Universe evolved at this crucial stage. JKCS041 is found at the cusp of when scientists think galaxy clusters can exist in the early Universe based on how long it should take for them to assemble. Therefore, studying its characteristics - such as composition, mass, and temperature - will reveal more about how the Universe took shape. "This object is close to the distance limit expected for a galaxy cluster," said Stefano Andreon of the National Institute for Astrophysics (INAF) in Milan, Italy. "We don't think gravity can work fast enough to make galaxy clusters much earlier." Distant galaxy clusters are often detected first with optical and infrared observations that reveal their component galaxies dominated by old, red stars. JKCS041 was originally detected in 2006 in a survey from the United Kingdom Infrared Telescope (UKIRT). The distance to the cluster was then determined from optical and infrared observations from UKIRT, the Canada-France-Hawaii telescope in Hawaii and NASA's Spitzer Space Telescope. Infrared observations are important because the optical light from the galaxies at large distances is shifted into infrared wavelengths because of the expansion of the universe. The Chandra data were the final - but crucial - piece of evidence as they showed that JKCS041 was, indeed, a genuine galaxy cluster. The extended X-ray emission seen by Chandra shows that hot gas has been detected between the galaxies, as expected for a true galaxy cluster rather than one that has been caught in the act of forming. Also, without the X-ray observations, the possibility remained that this object could have been a blend of different groups of galaxies along the line of sight, or a filament, a long stream of galaxies and gas, viewed front on. The mass and temperature of the hot gas detected estimated from the Chandra observations rule out both of those alternatives. The extent and shape of the X-ray emission, along with the lack of a central radio source argue against the possibility that the X-ray emission is caused by scattering of cosmic microwave background light by particles emitting radio waves. It is not yet possible, with the detection of just one extremely distant galaxy cluster, to test cosmological models, but searches are underway to find other galaxy clusters at extreme distances. "This discovery is exciting because it is like finding a Tyrannosaurus Rex fossil that is much older than any other known," said co-author Ben Maughan, from the University of Bristol in the United Kingdom. "One fossil might just fit in with our understanding of dinosaurs, but if you found many more, you would have to start rethinking how dinosaurs evolved. The same is true for galaxy clusters and our understanding of cosmology." The previous record holder for a galaxy cluster was 9.2 billion light years away, XMMXCS J2215.9-1738, discovered by ESA's XMM-Newton in 2006. This broke the previous distance record by only about 0.1 billion light years, while JKCS041 surpasses XMMXCS J2215.9 by about ten times that. "What's exciting about this discovery is the astrophysics that can be done with detailed follow-up studies," said Andreon. Among the questions scientists hope to address by further studying JKCS041 are: What is the build-up of elements (such as iron) like in such a young object? Are there signs that the cluster is still forming? Do the temperature and X-ray brightness of such a distant cluster relate to its mass in the same simple way as they do for nearby clusters? The paper describing the results on JKCS041 from Andreon and his colleagues will appear in an upcoming issue of the journal Astronomy and Astrophysics. NASA's Marshall Space Flight Center in Huntsville, Ala., manages the Chandra program for NASA's Science Mission Directorate in Washington, DC. The Smithsonian Astrophysical Observatory controls Chandra's science and flight operations from Cambridge, Mass.

The Generation of the Distant Kuiper Belt by Planet Nine from an Initially Broad Perihelion Distribution

NASA Astrophysics Data System (ADS)

Khain, Tali; Batygin, Konstantin; Brown, Michael E.

2018-06-01

The observation that the orbits of long-period Kuiper Belt objects (KBOs) are anomalously clustered in physical space has recently prompted the Planet Nine hypothesis—the proposed existence of a distant and eccentric planetary member of our solar system. Within the framework of this model, a Neptune-like perturber sculpts the orbital distribution of distant KBOs through a complex interplay of resonant and secular effects, such that in addition to perihelion-circulating objects, the surviving orbits get organized into apsidally aligned and anti-aligned configurations with respect to Planet Nine’s orbit. In this work, we investigate the role of Kuiper Belt initial conditions on the evolution of the outer solar system using numerical simulations. Intriguingly, we find that the final perihelion distance distribution depends strongly on the primordial state of the system, and we demonstrate that a bimodal structure corresponding to the existence of both aligned and anti-aligned clusters is only reproduced if the initial perihelion distribution is assumed to extend well beyond ∼36 au. The bimodality in the final perihelion distance distribution is due to the existence of permanently stable objects, with the lower perihelion peak corresponding to the anti-aligned orbits and the higher perihelion peak corresponding to the aligned orbits. We identify the mechanisms that enable the persistent stability of these objects and locate the regions of phase space in which they reside. The obtained results contextualize the Planet Nine hypothesis within the broader narrative of solar system formation and offer further insight into the observational search for Planet Nine.

Nemesis reconsidered

NASA Astrophysics Data System (ADS)

Melott, Adrian L.; Bambach, Richard K.

2010-09-01

The hypothesis of a companion object (Nemesis) orbiting the Sun was motivated by the claim of a terrestrial extinction periodicity, thought to be mediated by comet showers. The orbit of a distant companion to the Sun is expected to be perturbed by the Galactic tidal field and encounters with passing stars, which will induce variation in the period. We examine the evidence for the previously proposed periodicity, using two modern, greatly improved paleontological data sets of fossil biodiversity. We find that there is a narrow peak at 27 Myr in the cross-spectrum of extinction intensity time series between these independent data sets. This periodicity extends over a time period nearly twice that for which it was originally noted. An excess of extinction events is associated with this periodicity at 99 per cent confidence. In this sense we confirm the originally noted feature in the time series for extinction. However, we find that it displays extremely regular timing for about 0.5 Gyr. The regularity of the timing compared with earlier calculations of orbital perturbation would seem to exclude the Nemesis hypothesis as a causal factor.

Faint Compact Galaxy in the Early Universe

NASA Image and Video Library

2015-12-03

This is a Hubble Space Telescope view of a very massive cluster of galaxies, MACS J0416.1-2403, located roughly 4 billion light-years away and weighing as much as a million billion suns. The cluster's immense gravitational field magnifies the image of galaxies far behind it, in a phenomenon called gravitational lensing. The inset is an image of an extremely faint and distant galaxy that existed only 400 million years after the big bang. It was discovered by Hubble and NASA's Spitzer Space Telescope. The gravitational lens makes the galaxy appear 20 times brighter than normal. The galaxy is comparable in size to the Large Magellanic Cloud (LMC), a diminutive satellite galaxy of our Milky Way. It is rapidly making stars at a rate ten times faster than the LMC. This might be the growing core of what was to eventually evolve into a full-sized galaxy. The research team has nicknamed the object Tayna, which means "first-born" in Aymara, a language spoken in the Andes and Altiplano regions of South America. http://photojournal.jpl.nasa.gov/catalog/PIA20054

Determination of the Size and Depth of Craters on the Moon

ERIC Educational Resources Information Center

Grubelnik, Vladimir; Marhl, Marko; Repnik, Robert

2018-01-01

Experimental work in the research of astronomical phenomena is often difficult or even impossible because of long-lasting processes or too distant objects and correspondingly too expensive equipment. In this paper, we present an example of observation of the Moon, which is our nearest astronomic object and therefore does not require professional…

2012 DR30, The Most Distant Solar System Object

NASA Astrophysics Data System (ADS)

Kiss, Csaba; Szabó, G.; Pál, A.; Kiss, L.; Sárneczky, K.; Müller, T.; Vilenius, E.; Santos-Sanz, P.; Lellouch, E.; Conn, B.; Ortiz, J.; Duffard, R.; Morales, N.; Horner, J.; Bannister, M.; Stansberry, J.

2012-10-01

2012 DR30, the most distant TNO in the Solar System (a=1103 AU) has recently been observed with the Herschel Space Observatory. Radiometric model results using the far-infrared fluxes and visual range data show a dark and cratered surface (p_V = 6%) and provide a diameter of 200km. If considered as a Centaur, this is the fifth largest object known in this dynamical class. Recent visual range measurements indicate the presence of methane ice on the surface, a feature that has been seen previously for objects with diameters of >=1000km only (like Eris, Makemake and Pluto). The presence of methane ice can be explained assuming that the object spent most of its lifetime in a very cold environment and has been recently placed to its present orbit. This scenario is in agreement with the results of a dynamical study of the object's orbit, also suggesting an Oort-cloud origin. This research has been supported by the following grants: (1) The PECS program of the European Space Agency (ESA) and the Hungarian Space Office, PECS-98073; (2) C.K. and A.P. acknowledges the support of the Bolyai Research Fellowship of the Hungarian Academy of Sciences.

Structure and substructure analysis of DAFT/FADA galaxy clusters in the [0.4–0.9] redshift range

DOE Office of Scientific and Technical Information (OSTI.GOV)

Guennou, L.; et al.

2014-01-17

Context. The DAFT/FADA survey is based on the study of ~90 rich(masses found in the literature >2 x 10^14 M_⊙)and moderately distant clusters (redshifts 0.4 < z < 0.9), all withHST imaging data available. This survey has two main objectives: to constrain dark energy(DE) using weak lensing tomography on galaxy clusters and to build a database (deepmulti-band imaging allowing photometric redshift estimates, spectroscopic data, X-raydata) of rich distant clusters to study their properties.

NASA's Webb Telescope "chilling out" in Houston for the summer

NASA Image and Video Library

2017-12-08

NASA’s James Webb Space Telescope was placed in Johnson Space Center’s historic Chamber A on June 20, 2017, to prepare for its final three months of testing in a cryogenic vacuum that mimics temperatures in space. Engineers will perform the test to prove that the telescope can operate in space at these temperatures. Chamber A will simulate an environment where the telescope will experience extreme cold -- around 37 Kelvin (minus 236 degrees Celsius or minus 393 degrees Fahrenheit). In space, the telescope must be kept extremely cold, in order to be able to detect the infrared light from very faint, distant objects. To protect the telescope from external sources of light and heat (like the sun, Earth, and moon), as well as from heat emitted by the observatory, a five-layer, tennis court-sized sunshield acts like a parasol that provides shade. The sunshield separates the observatory into a warm, sun-facing side (reaching temperatures close to 400 degrees Fahrenheit) and a cold side (185 degrees below zero). The sunshield blocks sunlight from interfering with the sensitive telescope instruments. Read more: go.nasa.gov/2sZAilS NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

New Horizons High-Phase Observations of Distant Kuiper Belt Objects

NASA Astrophysics Data System (ADS)

Verbiscer, A.; Porter, S.; Spencer, J. R.; Buie, M. W.; Benecchi, S.; Weaver, H. A., Jr.; Buratti, B. J.; Ennico Smith, K.; Olkin, C.; Stern, S. A.; Young, L. A.; Cheng, A. F.

2017-12-01

From its unique vantage point far from the Sun, NASA's New Horizons spacecraft has observed Kuiper Belt Objects at separations ranging from 0.1 to 70 AU, and at solar phase angles far larger than those attainable from Earth. We have constructed the first KBO solar phase curves with substantial phase angle coverage for targets including Haumea, Makemake, Quaoar, Arawn (Porter et al. 2016, Astrophys. J. Lett. 828, L15), and 2002 MS4. We compare the phase functions of these KBOs with those of objects in the Pluto system and other Solar System bodies such as comets, asteroids, and icy satellites. For KBOs with known geometric albedos, these measurements enable calculation of the phase integral, an important photometric property that characterizes the energy balance on a distant KBO surface. During its approach to 2014 MU69, and following its close encounter on 1 January 2019, New Horizons will continue to exploit its capabilities as NASA's only observatory within the Kuiper Belt itself.

Foggy perception slows us down

PubMed Central

Pretto, Paolo; Bresciani, Jean-Pierre; Rainer, Gregor; Bülthoff, Heinrich H

2012-01-01

Visual speed is believed to be underestimated at low contrast, which has been proposed as an explanation of excessive driving speed in fog. Combining psychophysics measurements and driving simulation, we confirm that speed is underestimated when contrast is reduced uniformly for all objects of the visual scene independently of their distance from the viewer. However, we show that when contrast is reduced more for distant objects, as is the case in real fog, visual speed is actually overestimated, prompting drivers to decelerate. Using an artificial anti-fog—that is, fog characterized by better visibility for distant than for close objects, we demonstrate for the first time that perceived speed depends on the spatial distribution of contrast over the visual scene rather than the global level of contrast per se. Our results cast new light on how reduced visibility conditions affect perceived speed, providing important insight into the human visual system. DOI: http://dx.doi.org/10.7554/eLife.00031.001 PMID:23110253

Cosmic strings in the real sky

NASA Technical Reports Server (NTRS)

Hogan, Craig J.

1987-01-01

Observational strategies for finding effects associated with the gravitational lensing of distant objects by strings are discussed. In particular, a proposed search program at Steward Observatory to find chains of Galaxy image pairs is described.

Recovering Neptune 170 Years After its Initial Discovery

NASA Astrophysics Data System (ADS)

Myles, Justin

2017-01-01

Recent work by Trujillo and Shephard (2014) and Batygin and Brown (2016) has shown an as-yet unexplained clustering of the periapse vectors of the most distant Kuiper Belt objects. This unusual clustering has motivated the search for an unseen perturbing planet that is responsible for maintaining the alignment. As a proof of concept of a technique for locating unseen solar system planets, we use dynamical N-body integrations to simulate the orbital dynamics of distant Kuiper Belt objects, with the aim of determining the orbital parameters of Neptune (which, for the sake of exercise, we assume is, as-yet, undiscovered). In this poster, we determine the accuracy with which the perturbing planet’s orbital elements and sky location can be determined, and we show how the lessons learned can improve the search strategy for potentially undiscovered trans-Neptunian planets.

Stand-off molecular composition analysis

NASA Astrophysics Data System (ADS)

Hughes, Gary B.; Lubin, Philip; Meinhold, Peter; O'Neill, Hugh; Brashears, Travis; Zhang, Qicheng; Griswold, Janelle; Riley, Jordan; Motta, Caio

2015-09-01

Molecular composition of distant stars is explored by observing absorption spectra. The star produces blackbody radiation that passes through the molecular cloud of vaporized material surrounding the star. Characteristic absorption lines are discernible with a spectrometer, and molecular composition is investigated by comparing spectral observations with known material profiles. Most objects in the solar system—asteroids, comets, planets, moons—are too cold to be interrogated in this manner. Molecular clouds around cold objects consist primarily of volatiles, so bulk composition cannot be probed. Additionally, low volatile density does not produce discernible absorption lines in the faint signal generated by low blackbody temperatures. This paper describes a system for probing the molecular composition of cold solar system targets from a distant vantage. The concept utilizes a directed energy beam to melt and vaporize a spot on a distant target, such as from a spacecraft orbiting the object. With sufficient flux (~10 MW/m2), the spot temperature rises rapidly (to ~2 500 K), and evaporation of all materials on the target surface occurs. The melted spot creates a high-temperature blackbody source, and ejected material creates a molecular plume in front of the spot. Bulk composition is investigated by using a spectrometer to view the heated spot through the ejected material. Spatial composition maps could be created by scanning the surface. Applying the beam to a single spot continuously produces a borehole, and shallow sub-surface composition profiling is also possible. Initial simulations of absorption profiles with laser heating show great promise for molecular composition analysis.

Contact in an Expanding Universe: An Instructive Exercise in Dynamic Geometry

ERIC Educational Resources Information Center

Zimmerman, Seth

2010-01-01

The particular problem solved in this paper is that of calculating the time required to overtake a distant object receding under cosmic expansion, and the speed at which that object is passed. This is a rarely investigated problem leading to some interesting apparent paradoxes. We employ the problem to promote a deeper understanding of the dynamic…

Gravitational Lensing by Clusters of Galaxies

NASA Astrophysics Data System (ADS)

Tyson, J.; Murdin, P.

2000-11-01

CLUSTERS OF GALAXIES are massive and relatively rare objects containing hundreds of galaxies. Their huge mass—dominated by DARK MATTER—bends light from all background objects, systematically distorting the images of thousands of distant galaxies (shear). This observed gravitational lens distortion can be inverted to produce an `image' of the mass in the foreground cluster of galaxies. Most of the...

Creation of a Web-Based Lecture Series for Psychiatry Clerkship Students: Initial Findings

ERIC Educational Resources Information Center

Martin, Vicki L.; Bennett, David S.

2004-01-01

Objective: In recent years, the trend in medical education has been to utilize clerkship settings outside the medical school. Subsequently, students rotate at distant sites from the main campus and have lectures of varying quantity and quality. The objective of the present study was to standardize the core didactic experience for students in the…

The Generation-X X-ray Observatory Vision Mission and Technology Study

NASA Technical Reports Server (NTRS)

Figueroa-Feliciano, Enectali

2004-01-01

The new frontier in astrophysics is the study of the birth and evolution of the first stars, galaxies and black holes in the early Universe. X-ray astronomy opens a window into these objects by studying the emission from black holes, supernova explosions and the gamma-ray burst afterglows of massive stars. However, such objects are beyond the grasp of current or near-future observatories. X-ray imaging and spectroscopy of such distant objects will require an X-ray telescope with large collecting area and high angular resolution. Our team has conceived the Generation-X Vision Mission based on an X-ray observatory with 100 sq m collecting area at 1 keV (1000 times larger than Chandra) and 0.1 arcsecond angular resolution (several times better than Chandra and 50 times better than the Constellation-X resolution goal). Such an observatory would be capable of detecting the earliest black holes and galaxies in the Universe, and will also study extremes of density, gravity, magnetic fields, and kinetic energy which cannot be created in laboratories. NASA has selected the Generation-X mission for study under its Vision Mission Program. We describe the studies being performed to develop the mission concept and define candidate technologies and performance requirements for Generation-X. The baseline Generation-X mission involves four 8m diameter X-ray telescopes operating at Sun-Earth L2. We trade against an alternate concept of a single 26m diameter telescope with focal plane instruments on a separate spacecraft. A telescope of this size will require either robotic or human-assisted in-flight assembly. The required effective area implies that extremely lightweight grazing incidence X-ray optics must be developed. To achieve the required aerial density of at least 100 times lower than in Chandra, we will study 0.1mm thick mirrors which have active on-orbit figure control. We discuss the suite of required detectors, including a large FOV high angular resolution imager, a cryogenic imaging spectrometer and a grating spectrometer. We outline the development roadmap to confront the many technological challenges far implementing the Generation-X mission.

Primary Hepatic Malignant Fibrous Histiocytoma on PET/CT.

PubMed

Liu, Yachao; Xu, Baixuan

2018-06-01

Malignant fibrous histiocytoma is mainly presented in extremities, less commonly in posterior peritoneum, but primary presented in liver is very rare and often with a poor prognosis because of its high aggression. The features of clinical presentations and images are variable and the pre-operative diagnosis is difficult. Here, we report a primary hepatic malignant fibrous histiocytoma patient with no distant metastasis showed on pre-operative F-FDG PET/CT, however with many metastases showed on the post-operative F-FDG PET/CT.

Addison's disease as a presentation of metastatic malignant melanoma.

PubMed

Srinivasan, B; Patel, M; Ethunandan, M; Ilankovan, V

2016-01-01

Melanoma accounts for 5% of all skin cancers. The risk of metastasis is related to the thickness of the tumour, and can affect local, regional and distant sites. Adrenal metastasis from melanoma of the head and neck is uncommon and often asymptomatic. Addison's disease as a presentation of metastatic melanoma is extremely rare and we are unaware of previous reports in the world literature. We report a case of a patient with metastatic melanoma presenting with signs and symptoms of Addison's disease.

Hubble Portrait of the Double

NASA Image and Video Library

1998-03-28

This is the clearest view yet of the distant planet Pluto and its moon, Charon, as revealed by NASA Hubble Space Telescope. The image was taken by the European Space Agency Faint Object Camera on February 21, 1994.

Average dimension and magnetic structure of the distant Venus magnetotail

NASA Technical Reports Server (NTRS)

Saunders, M. A.; Russell, C. T.

1986-01-01

The first major statistical investigation of the far wake of an unmagnetized object embedded in the solar wind is reported. The investigation is based on Pioneer Venus Orbiter magnetometer data from 70 crossings of the Venus wake at altitudes between 5 and 11 Venus radii during reasonably steady IMF conditions. It is found that Venus has a well-developed-tail, flaring with altitude and possibly broader in the direction parallel to the IMF cross-flow component. Tail lobe field polarities and the direction of the cross-tail field are consistent with tail accretion from the solar wind. Average values for the cross-tail field (2 nT) and the distant tail flux (3 MWb) indicate that most distant tail field lines close across the center of the tail and are not rooted in the Venus ionosphere. The findings are illustrated in a three-dimensional schematic.

A Galaxy is Born in a Swirling Hydrogen Cloud

NASA Astrophysics Data System (ADS)

1995-10-01

Astronomers from the University of Leiden have discovered an extremely distant, enormous gas cloud. It is probably a `cocoon' from which one or more galaxies are in the process of being born, soon after the Big Bang. The observations also indicate that this gas cloud is slowly rotating, an entirely new result of great cosmological significance. The discovery was made with the ESO 3.5-metre New Technology Telescope (NTT) at La Silla in Chile by a team consisting of Rob van Ojik, Huub Röttgering, Chris Carilli, George Miley and Malcolm Bremer from Leiden Observatory (The Netherlands) and Duccio Macchetto of the European Space Agency (ESA) stationed in Baltimore, U.S.A. Their extensive observations are reported in an article accepted for publication in the professional European journal `Astronomy and Astrophysics' and also as a chapter of van Ojik's Ph.D. thesis which is defended at the University of Leiden on October 25. This exciting result casts new light on one of the most important questions of modern cosmology, i.e. how lumpy galaxies were `born' out of the extremely smooth fireball produced during the Big Bang . Discovery of a Very Distant Infant Galaxy Among the most important questions which astronomers are now attempting to answer are when and how did galaxies form. This involves a very difficult and time-consuming study of the most distant galaxies that can be perceived with modern telescopes. Because of the extremely long time it has taken their light to reach us, we now observe them, as they looked like soon after the Big Bang. For some years, the Leiden group has been using a combination of observational techniques at radio and optical telescopes to pinpoint very distant galaxies. In fact, this group has discovered more than half of the sixty most distant galaxies now known. The majority of these remote galaxies were first detected because of their strong radio emission and many of them were later found to be embedded in clouds of hot gas, mostly consisting of hydrogen. This gas radiates intensely at characteristic wavelengths (colours), also in the optical and infrared parts of the spectrum. These characteristic emission features are shifted towards longer wavelengths when compared with the emission from similar gas measured in laboratories on the Earth. This `redshift' (Doppler-effect) arises because the distant galaxies and their surrounding gas clouds recede from us at high velocities that are due to the general expansion of the Universe. The larger the distance, the higher is the velocity and the larger the redshift. The redshift is the standard yardstick which astronomers use to measure distance of galaxies [1]. The distant galaxy 1243+036 (this designation indicates its location in the sky) is one of the half dozen most distant galaxies found so far. It was first detected by the Leiden group three years ago by means of the ESO telescopes at La Silla. Its redshift is z = 3.6, corresponding to a `look-back' time of about 90 percent of the age of the Universe. In other words, light now reaching the Earth from an object at this large distance was emitted when the age of the Universe was only about 10 percent of what it is now. It is believed that most galaxies and groups of galaxies formed at this early epoch or soon thereafter. The Hydrogen Cloud around 1243+036 The spectacular properties of galaxy 1243+036 were first revealed when long-exposure images with the SUSI camera at the ESO 3.5-metre NTT showed an extensive, surrounding cloud of gas. The redshifted Lyman-alpha emission by the hydrogen atoms in this cloud was observed with the EMMI instrument at the same telescope in the spectroscopic mode during a 4-hour exposure. These observations profited from excellent sky conditions; in both cases, the seeing was 0.6 arcseconds. Moreover, the galaxy was observed in the radio region of the spectrum with the Very Large Array of the US National Radio Astronomy Observatory in New Mexico, U.S.A. When the optical and radio images are combined, it is seen that a radio `jet' emerges from the centre of the galaxy and interacts vigorously with the inner region of the gas cloud. This jet is believed to be a narrow stream of high-energy electrons spewed out at the edge of a black hole located at the center of the galaxy. Such jets are often seen in distant radio galaxies. But the most intriguing property of 1243+036 is revealed by the faint glow from the hydrogen atoms in the outer regions of the gas cloud, now detected on the EMMI spectra. The extent of this faint light shows that the size of the gas cloud is almost 500,000 light years, i.e. many times larger than the clouds seen around normal galaxies. The mass of this enormous cloud probably exceeds 10,000 million times that of the Sun. This Press Release is accompanied by ESO Press Photo 32/95 [86K] with an explanatory text that shows these features. The Giant Hydrogen Cloud Rotates ! Even more exciting, the astronomers also found that the measured wavelength of the Lyman-alpha emission from the hydrogen gas differs slightly, but systematically from one side of the cloud to the other. The difference implies that the two extremities of the cloud are rushing away from us with speeds that differ by 450 km/s. This is the first time ever that organized motion in such a large and distant structure has been detected and measured. According to van Ojik and his colleagues, the most likely explanation of the variation in speed is that the huge gas cloud rotates in such a way that the Northwest edge is receding and the Southeast edge is approaching, relative to the embedded galaxy at its centre. The measured size of the cloud and the rotation velocity indicate that it has made about one complete revolution since the Big Bang. The cloud around 1243+036 may be a relic of the earliest stages of formation of this galaxy. The observed motion may in fact represent a typical state of the gas around primeval galaxies in the young Universe, before it is affected by the violent motion of the material that is now observed as a radio jet. As this cloud rotates, gas falls towards the centre, feeding mass and energy to the black hole while smaller clumps of gas contract and form stars. In this way, the enormous, rotating gas cloud ``gives birth'' to the galaxy and possibly to an entire group or cluster of galaxies. Some theories of galaxy and cluster formation predict the existence of such giant rotating clouds in the early Universe. The discovery of the cloud around the galaxy 1243+036 with exactly these properties provides the first evidence in favour of such models. Note [1] See ESO Press Releases 09/95 of 17 August 1995 and 11/95 of 15 September 1995. How to obtain ESO Press Information ESO Press Information is made available on the World-Wide Web (URL: http://www.eso.org../). ESO Press Photos may be reproduced, if credit is given to the European Southern Observatory.

A Ninth Planet in Our Solar System?

NASA Astrophysics Data System (ADS)

Kohler, Susanna

2016-01-01

The recent discovery that the orbits of some Kuiper belt objects (KBOs) share properties has proved puzzling. A pair of scientists have now proposed a bold explanation: there may be a planet-sized object yet undetected in our solar system.Mysterious ClusteringKBOs, the population of mainly small objects beyond Neptune, have proven an especially interesting subject of study in the last decade as many small, distant bodies (such as Eris, the object that led to the demotion of Pluto to dwarf planet) have been discovered.Previous studies have recently discovered that some especially distant KBOs those that orbit with semimajor axes of a 150 AU, nearly four times that of Pluto all cross the ecliptic at a similar phase in their elliptical trajectories. This is unexpected, since gravitational tugs from the giant planets should have randomized this parameter over our solar systems multi-billion-year lifespan.Physical alignment of the orbits of Kuiper belt objects with a 250 AU (and two objects with a 150 AU that are dynamically stable). [Batygin Brown 2016]Two scientists at California Institute of Technology, Konstantin Batygin and Michael Brown (you might recognize Brown as the man who killed Pluto) have now increased the mystery. In a recently published a study, they demonstrate that for KBOs that have orbits with a 250 AU, the orbits are actually physically aligned.To explain this unexpected alignment which Batygin and Brown calculate has only a 0.007% probability of having occurred by chance the authors ask an exciting question: could this be caused by the presence of an unseen, large, perturbing body further out in the solar system?Simulating a Ninth PlanetThe authors test this hypothesis by carrying out both analytical calculations and numerical N-body simulations designed to determine if the gravitational influence of a distant, planetary-mass companion can explain the behavior we observe from the large-orbit KBOs.Simulation of the effect of a distant planet (M = 10 M, a = 700 AU, and e = 0.6) on KBOs; click for a better look! The perihelion position of KBOs with a 250 AU clusters around 180 from the perihelion position of the perturbing planet. More-transparent points are less observable. [Batygin Brown 2016]The result? It turns out that such a distant planet can cause the orbits of KBOs with a 250 AU to all align in the opposite direction of the orbit of the planet. Whats more, the gravitational pull of this planet can also explain other unresolved puzzles about the Kuiper belt, such as the presence of high-perihelion Sedna-like objects, as well as a population of KBOs weve observed that have misaligned orbits.Unfortunately, Batygin and Brown found it isnt possible to exactly determine the properties of the possible planet, since multiple combinations of its mass, eccentricity, and semimajor axis can create the same observational results. That said, they believe the distant perturbers orbit is highly eccentric, its orbital inclination is low, and its fairly massive (since anything less than an Earth-mass wont create the observed clustering of KBO orbits within the age of the solar system).As an example, one possible set of parameters that approximately reproduces the observed KBO orbits is the following:planet mass of 10 Earth-massessemi-major axis of a = 700 AUeccentricity of e = 0.6This would correspond to a perihelion distance of 280 AU and an aphelion distance of 1,120 AU.The authors speculate such a planet might have been formed closer in to the Sun, but it was ejected later on during our solar systems evolution. Interactions with the Suns birth cluster could have then caused the planet to be retained in a bound orbit.Future TestsOur solar system on a logarithmic scale (click for the full view). KBOs with a semimajor axis of a 250 AU may be being aligned by a planetary-mass body with an even more distant orbit. [NASA]How can we test this hypothesis of a ninth planet? Obviously, directly observing the planet would confirm its presence. But the authors model has an additional testable hypothesis: if its correct, there should be a population of high-perihelion Kuiper belt objects that dont exhibit the same alignment of their orbits as the KBOs we know about, but instead have opposite-aligned orbits. If we discover such a collection of objects, that would be an excellent confirmation of this model.The authors caution that their work is preliminary, and additional investigation will be required to better understand the possibilities presented here. But with any luck, future theoretical work, as well as observational tests of this models predictions, will help us determine whether there might be a distant ninth planet in our solar system!BonusCheck out this video (created with WWT!), which walks us first through a view of the six aligned KBO orbits, then shows a possible orbit for the hypothesized planet, and then shows an additional population of already-discovered objects (also predicted by the model) that have orbits perpendicular both to the plane of the solar system and to the planets orbit. [Caltech/Robert Hurt]http://aasnova.org/wp-content/uploads/2016/01/Planet9_anim_720.m4vCitationKonstantin Batygin and Michael E. Brown 2016 AJ 151 22. doi:10.3847/0004-6256/151/2/22

Record-Breaking Radio Astronomy Project to Measure Sky with Extreme Precision

NASA Astrophysics Data System (ADS)

2009-11-01

Astronomers will tie together the largest collection of the world's radio telescopes ever assembled to work as a single observing tool in a project aimed at improving the precision of the reference frame scientists use to measure positions in the sky. The National Science Foundation's Very Long Baseline Array (VLBA) will be a key part of the project, which is coordinated by the International VLBI Service for Geodesy and Astrometry. For 24 hours, starting Wednesday, November 18, and ending Thursday, November 19, 35 radio telescopes located on seven continents will observe 243 distant quasars. The quasars, galaxies with supermassive black holes at their cores, are profuse emitters of radio waves, and also are so distant that, despite their actual motions in space, they appear stationary as seen from Earth. This lack of apparent motion makes them ideal celestial landmarks for anchoring a grid system, similar to earthly latitude and longitude, used to mark the positions of celestial objects. Data from all the radio telescopes will be combined to make them work together as a system capable of measuring celestial positions with extremely high precision. The technique used, called very long baseline interferometry (VLBI), has been used for decades for both astronomical and geodetic research. However, no previous position-measuring observation has used as many radio telescopes or observed as many objects in a single session. The previous record was a 23-telescope observation. At a meeting in Brazil last August, the International Astronomical Union adopted a new reference frame for celestial positions that will be used starting on January 1. This new reference frame uses a set of 295 quasars to define positions, much like surveyor's benchmarks in a surburban subdivision. Because even with 35 radio telescopes around the world, there are some gaps in sky coverage, the upcoming observation will observe 243 of the 295. By observing so many quasars in a single observing session, problems of linking positions from one observing session to another can be avoided, the astronomers say. The result will be a much stronger, more precise, reference grid. Telescopes in Asia, Australia, Europe, North America, South America, Antarctica, and in the Pacific will participate. Improving the celestial positional grid will allow astronomers better to pinpoint the locations and measure the motions of objects in the sky. As astronomers increasingly study objects using multiple telescopes observing at different wavelengths, such as visible light, radio, infrared, etc., the improved positional grid will allow more accurate overlaying of the different images. The improved celestial reference frame also strengthens a terrestrial reference frame used for radio-telescope measurements that contribute to geophysical research. The precise geodetic measurements help geophysicists understand phenomena such as plate tectonics, earth tides, and processes that affect our planet's orientation in space. The VLBA is a continent-wide radio telescope system with 10, 240-ton dish antennas ranging from Hawaii to the Virgin Islands. Operated from the National Radio Astronomy Observatory's Pete V. Domenici Science Operations Center in Socorro, New Mexico, the VLBA offers the greatest resolving power, or ability to see fine detail, of any telescope in astronomy. The multi-telescope observation will be accompanied by public-outreach activities in celebration of the International Year of Astronomy. A public web page devoted to the observation will be hosted at Bordeaux Observatory, and some of the participating telescopes will have webcams available.

Distant Galaxies in Goods North

NASA Image and Video Library

2014-01-07

The view is a composite of images taken in visible and near-infrared light by NASA Hubble Space Telescope. Researchers have circled four unusually red objects that appear as they existed just 500 million years after the big bang.

Vision though afocal instruments: generalized magnification and eye-instrument interaction

NASA Astrophysics Data System (ADS)

Harris, William F.; Evans, Tanya

2018-04-01

In Gaussian optics all observers experience the same magnification, the instrument's angular magnification, when viewing distant objects though a telescope or other afocal instruments. However, analysis in linear optics shows that this is not necessarily so in the presence of astigmatism. Because astigmatism may distort and rotate images it is appropriate to work with generalized angular magnification represented by a 2 × 2 matrix. An expression is derived for the generalized magnification for an arbitrary eye looking through an arbitrary afocal instrument. With afocal instruments containing astigmatic refracting elements not all eyes experience the same generalized magnification; there is interaction between eye and instrument. Eye-instrument interaction may change as the instrument is rotated about its longitudinal axis, there being no interaction in particular orientations. A simple numerical example is given. For sake of completeness, expressions for generalized magnification are also presented in the case of instruments that are not afocal and objects that are not distant.

Genetic identification of a common collagen disease in Puerto Ricans via identity-by-descent mapping in a health system

PubMed Central

Belbin, Gillian Morven; Odgis, Jacqueline; Sorokin, Elena P; Yee, Muh-Ching; Kohli, Sumita; Glicksberg, Benjamin S; Gignoux, Christopher R; Wojcik, Genevieve L; Van Vleck, Tielman; Jeff, Janina M; Linderman, Michael; Schurmann, Claudia; Ruderfer, Douglas; Cai, Xiaoqiang; Merkelson, Amanda; Justice, Anne E; Young, Kristin L; Graff, Misa; North, Kari E; Peters, Ulrike; James, Regina; Hindorff, Lucia; Kornreich, Ruth; Edelmann, Lisa; Gottesman, Omri; Stahl, Eli EA; Cho, Judy H; Loos, Ruth JF; Bottinger, Erwin P; Nadkarni, Girish N; Abul-Husn, Noura S

2017-01-01

Achieving confidence in the causality of a disease locus is a complex task that often requires supporting data from both statistical genetics and clinical genomics. Here we describe a combined approach to identify and characterize a genetic disorder that leverages distantly related patients in a health system and population-scale mapping. We utilize genomic data to uncover components of distant pedigrees, in the absence of recorded pedigree information, in the multi-ethnic BioMe biobank in New York City. By linking to medical records, we discover a locus associated with both elevated genetic relatedness and extreme short stature. We link the gene, COL27A1, with a little-known genetic disease, previously thought to be rare and recessive. We demonstrate that disease manifests in both heterozygotes and homozygotes, indicating a common collagen disorder impacting up to 2% of individuals of Puerto Rican ancestry, leading to a better understanding of the continuum of complex and Mendelian disease. PMID:28895531

Chandra X-Ray Observatory Image of the Distant Galaxy, 3C294

NASA Technical Reports Server (NTRS)

2000-01-01

This most distant x-ray cluster of galaxies yet has been found by astronomers using Chandra X-ray Observatory (CXO). Approximately 10 billion light-years from Earth, the cluster 3C294 is 40 percent farther than the next most distant x-ray galaxy cluster. The existence of such a faraway cluster is important for understanding how the universe evolved. CXO's image reveals an hourglass-shaped region of x-ray emissions centered on the previously known central radio source (seen in this image as the blue central object) that extends outward for 60,000 light- years. The vast clouds of hot gas that surround such galaxies in clusters are thought to be heated by collapse toward the center of the cluster. Until CXO, x-ray telescopes have not had the needed sensitivity to identify such distant clusters of galaxies. Galaxy clusters are the largest gravitationally bound structures in the universe. The intensity of the x-rays in this CXO image of 3C294 is shown as red for low energy x-rays, green for intermediate, and blue for the most energetic x-rays. (Photo credit: NASA/loA/A. Fabian et al)

Star from the Lizard Constellation Photobombs Hubble Observation

NASA Image and Video Library

2017-12-08

In space, being outshone is an occupational hazard. This NASA/ESA Hubble Space Telescope image captures a galaxy named NGC 7250. Despite being remarkable in its own right — it has bright bursts of star formation and recorded supernova explosions— it blends into the background somewhat thanks to the gloriously bright star hogging the limelight next to it. The bright object seen in this Hubble image is a single and little-studied star named TYC 3203-450-1, located in the constellation of Lacerta (The Lizard). The star is much closer than the much more distant galaxy. Only this way can a normal star outshine an entire galaxy, consisting of billions of stars. Astronomers studying distant objects call these stars “foreground stars” and they are often not very happy about them, as their bright light is contaminating the faint light from the more distant and interesting objects they actually want to study. In this case, TYC 3203-450-1 is million times closer than NGC 7250, which lies more than 45 million light-years away from us. If the star were the same distance from us as NGC 7250, it would hardly be visible in this image. Credit: ESA/Hubble & NASA NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

Less aggressive disease in patients with primary squamous cell carcinomas of the thyroid gland and coexisting lymphocytic thyroiditis.

PubMed

Asik, Mehmet; Binnetoglu, Emine; Sen, Hacer; Gunes, Fahri; Muratli, Asli; Kankaya, Duygu; Uysal, Fatma; Sahin, Mustafa; Ukinc, Kubilay

2015-01-01

Primary squamous cell carcinoma (SCC) of the thyroid gland is extremely rare. Infrequently, primary SCC of the thyroid gland is accompanied by other thyroid diseases such as Hashimoto's thyroiditis (HT). Recently, studies have demonstrated that differentiated thyroid cancer with coexisting HT has a better prognosis. However, the prognosis of patients with primary SCC of the thyroid gland and coexistent HT has not been clearly identified. We compared the clinical characteristics and disease stages of patients with primary SCC with and without lymphocytic thyroiditis (LT). We reviewed reports of primary SCC of the thyroid gland published in the English literature. We identified 46 papers that included 17 cases of primary SCC of the thyroid gland with LT and 77 cases of primary SCC of the thyroid gland without LT. Lymph node metastasis and local invasion rates did not differ between these two groups. Distant metastases were absent in patients with LT, and were observed in 13 (16.9%) patients without LT. A greater proportion of patients without LT had advanced stage disease (stage IV A-B-C) than patients with LT (p < 0.05). Patients with primary SCC of the thyroid gland and coexisting LT had lower tumour-node-metastasis stage and frequency of distant metastasis than those without LT. Lymphocytic infiltration in patients with SCC appears to limit tumour growth and distant metastases.

Surface Compositions Across Pluto and Charon

NASA Technical Reports Server (NTRS)

Grundy, W. M.; Binzel, R. P.; Buratti, B. J.; Cook, J. C.; Cruikshank, D. P.; Dalle Ore, C. M.; Earle, A. M.; Ennico, K.; Howett, C. J. A.; Lunsford, A. W.;

Simulation and Measurement of Through-the-Earth, Extremely Low-Frequency Signals Using Copper-Clad Steel Ground Rods.

PubMed

Damiano, Nicholas William; Yan, Lincan; Whisner, Bruce; Zhou, Chenming

2017-01-01

The underground mining environment can greatly affect radio signal propagation. Understanding how the earth affects signal propagation is a key to evaluating communications systems used during a mine emergency. One type of communication system is through-the-earth, which can utilize extremely low frequencies (ELF). This paper presents the simulation and measurement results of recent National Institute for Occupational Safety and Health (NIOSH) research aimed at investigating current injection at ELF, and in particular, ground contact impedance. Measurements were taken at an outside surface testing location. The results obtained from modeling and measurement are characterized by electrode impedance, and the voltage received between two distant electrodes. This paper concludes with a discussion of design considerations found to affect low-frequency communication systems utilizing ground rods to inject a current into the earth.

Simulation and Measurement of Through-the-Earth, Extremely Low-Frequency Signals Using Copper-Clad Steel Ground Rods

PubMed Central

Damiano, Nicholas William; Yan, Lincan; Whisner, Bruce; Zhou, Chenming

2017-01-01

The underground mining environment can greatly affect radio signal propagation. Understanding how the earth affects signal propagation is a key to evaluating communications systems used during a mine emergency. One type of communication system is through-the-earth, which can utilize extremely low frequencies (ELF). This paper presents the simulation and measurement results of recent National Institute for Occupational Safety and Health (NIOSH) research aimed at investigating current injection at ELF, and in particular, ground contact impedance. Measurements were taken at an outside surface testing location. The results obtained from modeling and measurement are characterized by electrode impedance, and the voltage received between two distant electrodes. This paper concludes with a discussion of design considerations found to affect low-frequency communication systems utilizing ground rods to inject a current into the earth. PMID:29176916

Adaptation measures to drought in Mongolian rangeland: The long-distant movement of people and livestock

NASA Astrophysics Data System (ADS)

Kakinuma, K.; Kanae, S.

2015-12-01

Coping with droughts are one of the most important issues in arid and semi-arid regions. Mongolia, where are located in central Asia, are concerned the increase of droughts in the future (IPCC 2014). Mongolia has long history of livestock grazing. Herders have developed the mobile grazing systems to use spatiotemporal variable vegetation. Especially, they often take a rapid and long-distant movement to avoid drought condition ("otor" in Mongolia). The movement is a main adaptation measure to droughts for herders, and it would be applicable to other regions where will be increase the frequency of droughts in the future. However there are few knowledge about processes and actual conditions of the long-distant movement of herders and livestock across Mongolia. Therefore our objective is to discuss the long-distance movement as adaptation measures to droughts. Mongolia has a climatic gradient along the latitude; rainfall variability in southern regions are higher than that in northern regions. Previous theoretical studies predicted that rainfall variability affect the grazing strategies. Based on them, we established two hypotheses about the relationship between climatic variability and the form of long distant movement. (1) The long-distance movement likely occur in southern regions because the frequency of drought are higher in southern regions than in northern regions (2) Cooperation among herders, such as acceptance of livestock that from other prefectures, are likely occur in southern regions while exclusive management are likely occur in northern regions. We interviewed to local herders, decision makers about the long-distant movement, and investigated the number of livestock that across the border of prefectures in recent year across Mongolia. We will discuss long-distant movements as an adaptation measure to drought thorough these results.

MAD Adaptive Optics Imaging of High-luminosity Quasars: A Pilot Project

NASA Astrophysics Data System (ADS)

Liuzzo, E.; Falomo, R.; Paiano, S.; Treves, A.; Uslenghi, M.; Arcidiacono, C.; Baruffolo, A.; Diolaiti, E.; Farinato, J.; Lombini, M.; Moretti, A.; Ragazzoni, R.; Brast, R.; Donaldson, R.; Kolb, J.; Marchetti, E.; Tordo, S.

2016-08-01

We present near-IR images of five luminous quasars at z ˜ 2 and one at z ˜ 4 obtained with an experimental adaptive optics (AO) instrument at the European Southern Observatory Very Large Telescope. The observations are part of a program aimed at demonstrating the capabilities of multi-conjugated adaptive optics imaging combined with the use of natural guide stars for high spatial resolution studies on large telescopes. The observations were mostly obtained under poor seeing conditions but in two cases. In spite of these nonoptimal conditions, the resulting images of point sources have cores of FWHM ˜ 0.2 arcsec. We are able to characterize the host galaxy properties for two sources and set stringent upper limits to the galaxy luminosity for the others. We also report on the expected capabilities for investigating the host galaxies of distant quasars with AO systems coupled with future Extremely Large Telescopes. Detailed simulations show that it will be possible to characterize compact (2-3 kpc) quasar host galaxies for quasi-stellar objects at z = 2 with nucleus K-magnitude spanning from 15 to 20 (corresponding to absolute magnitude -31 to -26) and host galaxies that are 4 mag fainter than their nuclei.

Eccentricity growth and orbit flip in near-coplanar hierarchical three-body systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, Gongjie; Naoz, Smadar; Kocsis, Bence

2014-04-20

The secular dynamical evolution of a hierarchical three-body system in which a distant third object orbits around a binary has been studied extensively, demonstrating that the inner orbit can undergo large eccentricity and inclination oscillations. It was shown before that starting with a circular inner orbit, large mutual inclination (40°-140°) can produce long timescale modulations that drive the eccentricity to extremely large values and can flip the orbit. Here, we demonstrate that starting with an almost coplanar configuration, for eccentric inner and outer orbits, the eccentricity of the inner orbit can still be excited to high values, and the orbitmore » can flip by ∼180°, rolling over its major axis. The ∼180° flip criterion and the flip timescale are described by simple analytic expressions that depend on the initial orbital parameters. With tidal dissipation, this mechanism can produce counter-orbiting exoplanetary systems. In addition, we also show that this mechanism has the potential to enhance the tidal disruption or collision rates for different systems. Furthermore, we explore the entire e {sub 1} and i {sub 0} parameter space that can produce flips.« less

Impaired visibility: the air pollution people see

NASA Astrophysics Data System (ADS)

Hyslop, Nicole Pauly

Almost every home and office contains a portrayal of a scenic landscape whether on a calendar, postcard, photograph, or painting. The most sought after locations boast a scenic landscape right outside their window. No matter what the scene - mountains, skyscrapers, clouds, or pastureland - clarity and vividness are essential to the image. Air pollution can degrade scenic vistas, and in extreme cases, completely obscure them. Particulate matter suspended in the air is the main cause of visibility degradation. Particulate matter affects visibility in multiple ways: obscures distant objects, drains the contrast from a scene, and discolors the sky. Visibility is an environmental quality that is valued for aesthetic reasons that are difficult to express or quantify. Human psychology and physiology are sensitive to visual input. Visibility has been monitored throughout the world but there are few places where it is a protected resource. Existing health-based regulations are weak in terms of visibility protection. Various techniques, including human observation, light transmission measurements, digital photography, and satellite imaging, are used to monitor visibility. As with air pollution, trends in visibility vary spatially and temporally. Emissions from the developing world and large scale events such as dust storms and wildfires affect visibility around much of the globe.

The Origin Of Cosmic Rays And The Stars Of Berkeley 87

NASA Astrophysics Data System (ADS)

Turner, David G.; Majaess, D. J.; Lane, D. J.; Balam, D. D.

2010-01-01

Spectroscopic observations and the results of photometric monitoring are presented for members of the heavily-reddened, young, 1.2 kpc-distant, open cluster Berkeley 87, which is spatially coincident with the strongest source of cosmic rays in the northern sky. Many cluster members exhibit evidence for extreme loss of mass over their lifetimes: the M3 Ia supergiant BC Cyg has an evolutionary mass half that of stars at the main-sequence turnoff, the B2 Iabe emission-line supergiant HDE 229059 also has an evolutionary mass smaller than that of the main-sequence turnoff, the WO2 star WR 142, the only example of an oxygen sequence Wolf-Rayet star in an open cluster, displays evidence for variable, high velocity winds in its spectrum, the curious object V439 Cyg (B0: Vnne) appears to be an example of a recent binary merger, and Vatican Emission Star VES 203 (B0.5 Ve) displays a strong P Cygni signature in its Balmer line emission. It appears that heavy mass loss is a common factor associated with cluster stars. Could that be associated with the location of a cosmic ray production factory from the vicinity of Berkeley 87?

NASA Galaxy Mission Celebrates Sixth Anniversary

NASA Image and Video Library

2009-04-28

NASA Galaxy Evolution Explorer Mission celebrates its sixth anniversary studying galaxies beyond our Milky Way through its sensitive ultraviolet telescope, the only such far-ultraviolet detector in space. The mission studies the shape, brightness, size and distance of distant galaxies across 10 billion years of cosmic history, giving scientists a wealth of data to help us better understand the origins of the universe. One such object is pictured here, the galaxy NGC598, more commonly known as M33. The image shows a map of the recent star formation history of M33. The bright blue and white areas are where star formation has been extremely active over the past few million years. The patches of yellow and gold are regions where star formation was more active 100 million years ago. In addition, the ultraviolet image shows the most massive young stars in M33. These stars burn their large supply of hydrogen fuel quickly, burning hot and bright while emitting most of their energy at ultraviolet wavelengths. Compared with low-mass stars like our sun, which live for billions of years, these massive stars never reach old age, having a lifespan as short as a few million years. http://photojournal.jpl.nasa.gov/catalog/PIA12000

Far-field phase contrast from orbiting objects: Characterizing progenitors of binary mergers

NASA Astrophysics Data System (ADS)

Matthias, P.; Hofmann, R.

2018-05-01

We propose an idea to determine the size of a binary, composed of two compact stars or black holes, its diffractive power, the distance between components, and the distance to an observer, in exploiting the emergence of intensity contrast by free-space propagation when the phase of coherent light from a very distant background source is affected by diffraction. We assume that this effect can be characterized by the projected real part of an effective refractive index n . Here we model the according two-dimensional exit phase-map by a superposition of two Gaussians. In the extreme far field, phase information is captured by scaling functions which are analyzed here. Both spatial and temporal scanning of the intensity contrast are discussed. While the former mode can be used, e.g., to determine the distance to the observer, the latter allows, e.g., one to measure the overall diffractive power of the binary in terms of the particular dependence of a scaling curve on the projected spatial separation between the binary's components. Both modes of observation may be of relevance in monitoring the progenitor dynamics of binary collapse using radio telescopes.

Spectrum from Faint Galaxy IRAS F00183-7111

NASA Technical Reports Server (NTRS)

2003-01-01

NASA's Spitzer Space Telescope has detected the building blocks of life in the distant universe, albeit in a violent milieu. Training its powerful infrared eye on a faint object located at a distance of 3.2 billion light-years, Spitzer has observed the presence of water and organic molecules in the galaxy IRAS F00183-7111. With an active galactic nucleus, this is one of the most luminous galaxies in the universe, rivaling the energy output of a quasar. Because it is heavily obscured by dust (see visible-light image in the inset), most of its luminosity is radiated at infrared wavelengths.

The infrared spectrograph instrument onboard Spitzer breaks light into its constituent colors, much as a prism does for visible light. The image shows a low-resolution spectrum of the galaxy obtained by the spectrograph at wavelengths between 4 and 20 microns. Spectra are graphical representations of a celestial object's unique blend of light. Characteristic patterns, or fingerprints, within the spectra allow astronomers to identify the object's chemical composition and to determine such physical properties as temperature and density.

The broad depression in the center of the spectrum denotes the presence of silicates (chemically similar to beach sand) in the galaxy. An emission peak within the bottom of the trough is the chemical signature for molecular hydrogen. The hydrocarbons (orange) are organic molecules comprised of carbon and hydrogen, two of the most common elements on Earth. Since it has taken more than three billion years for the light from the galaxy to reach Earth, it is intriguing to note the presence of organics in a distant galaxy at a time when life is thought to have started forming on our home planet.

Additional features in the spectrum reveal the presence of water ice (blue), carbon dioxide ice (green) and carbon monoxide (purple) in both gas and solid forms. The magenta peak corresponds to singly ionized neon gas, a spectral line often used by astronomers as a diagnostic of star formation rates in distant galaxies.

The Spitzer spectrum is the result of only 14 minutes of integration time, highlighting the power of the infrared spectrograph to unlock the secrets of distant galaxies.

The AJCC 8th Edition Staging System for Soft Tissue Sarcoma of the Extremities or Trunk: A Cohort Study of the SEER Database.

PubMed

Cates, Justin M M

2018-02-01

Background: The AJCC recently published the 8th edition of its cancer staging system. Significant changes were made to the staging algorithm for soft tissue sarcoma (STS) of the extremities or trunk, including the addition of 2 additional T (size) classifications in lieu of tumor depth and grouping lymph node metastasis (LNM) with distant metastasis as stage IV disease. Whether these changes improve staging system performance is questionable. Patients and Methods: This retrospective cohort analysis of 21,396 adult patients with STS of the extremity or trunk in the SEER database compares the AJCC 8th edition staging system with the 7th edition and a newly proposed staging algorithm using a variety of statistical techniques. The effect of tumor size on disease-specific survival was assessed by flexible, nonlinear Cox proportional hazard regression using restricted cubic splines and fractional polynomials. Results: The slope of covariate-adjusted log hazards for sarcoma-specific survival decreases for tumors >8 cm in greatest dimension, limiting prognostic information contributed by the new T4 classification in the AJCC 8th edition. Anatomic depth independently provides significant prognostic information. LNM is not equivalent to distant, non-nodal metastasis. Based on these findings, an alternative staging system is proposed and demonstrated to outperform both AJCC staging schemes. The analyses presented also disclose no evidence of improved clinical performance of the 8th edition compared with the previous edition. Conclusions: The AJCC 8th edition staging system for STS is no better than the previous 7th edition. Instead, a proposed staging system based on histologic grade, tumor size, and anatomic depth shows significantly higher predictive accuracy, with higher model concordance than either AJCC staging system. Changes to existing staging systems should improve the performance of prognostic models. Until such improvements are documented, AJCC committees should refrain from modifying established staging schemes. Copyright © 2018 by the National Comprehensive Cancer Network.

Adaptive Nulling for Interferometric Detection of Planets

NASA Technical Reports Server (NTRS)

Lay, Oliver P.; Peters, Robert D.

2010-01-01

An adaptive-nulling method has been proposed to augment the nulling-optical- interferometry method of detection of Earth-like planets around distant stars. The method is intended to reduce the cost of building and aligning the highly precise optical components and assemblies needed for nulling. Typically, at the mid-infrared wavelengths used for detecting planets orbiting distant stars, a star is millions of times brighter than an Earth-sized planet. In order to directly detect the light from the planet, it is necessary to remove most of the light coming from the star. Nulling interferometry is one way to suppress the light from the star without appreciably suppressing the light from the planet. In nulling interferometry in its simplest form, one uses two nominally identical telescopes aimed in the same direction and separated laterally by a suitable distance. The light collected by the two telescopes is processed through optical trains and combined on a detector. The optical trains are designed such that the electric fields produced by an on-axis source (the star) are in anti-phase at the detector while the electric fields from the planet, which is slightly off-axis, combine in phase, so that the contrast ratio between the star and the planet is greatly decreased. If the electric fields from the star are exactly equal in amplitude and opposite in phase, then the star is effectively nulled out. Nulling is effective only if it is complete in the sense that it occurs simultaneously in both polarization states and at all wavelengths of interest. The need to ensure complete nulling translates to extremely tight demands upon the design and fabrication of the complex optical trains: The two telescopes must be highly symmetric, the reflectivities of the many mirrors in the telescopes and other optics must be carefully tailored, the optical coatings must be extremely uniform, sources of contamination must be minimized, optical surfaces must be nearly ideal, and alignments must be extremely precise. Satisfaction of all of these requirements entails substantial cost.

Exploring the Extreme Universe with the Fermi Gamma-Ray Space Telescope

NASA Technical Reports Server (NTRS)

Thompson, David J.; Digel, Seth W.; Racusin, Judith L.

2012-01-01

In ways similar to experiments in nuclear and particle physics, high-energy astrophysics usesgamma rays and energetic charged particles toprobe processes that involve large energy transfers.Since its launch in 2008, the international Fermi Gamma-Ray Space Telescope has been exploringnatural particle accelerators and the interactionsof high-energy particles in the universe. Withsources ranging from thunderstorms on Earth to galaxies and exploding stars in distant parts of the cosmos, the telescopes subjects of study are almostas diverse as were those of the scientist whose name it bears.

Exploring the limits to energy scaling and distant-target delivery of high-intensity midinfrared pulses

NASA Astrophysics Data System (ADS)

Panagiotopoulos, Paris; Kolesik, Miroslav; Moloney, Jerome V.

2016-09-01

We numerically investigate the scaling behavior of midinfrared filaments at extremely high input energies. It is shown that, given sufficient power, kilometer-scale, low-loss atmospheric filamentation is attainable by prechirping the pulse. Fully resolved four-dimensional (x y z t ) simulations show that, while in a spatially imperfect beam the modulation instability can lead to multiple hot-spot formation, the individual filaments are still stabilized by the recently proposed mechanism that relies on the temporal walk-off of short-wavelength radiation.

Complete genome sequence of the Antarctic Halorubrum lacusprofundi type strain ACAM 34

DOE PAGES

Anderson, Iain J.; DasSarma, Priya; Lucas, Susan; ...

2016-09-10

Halorubrum lacusprofundi is an extreme halophile within the archaeal phylum Euryarchaeota. The type strain ACAM 34 was isolated from Deep Lake, Antarctica. H. lacusprofundi is of phylogenetic interest because it is distantly related to the haloarchaea that have previously been sequenced. It is also of interest because of its psychrotolerance. We report here the complete genome sequence of H. lacusprofundi type strain ACAM 34 and its annotation. In conclusion, this genome is part of a 2006 Joint Genome Institute Community Sequencing Program project to sequence genomes of diverse Archaea.

Complete genome sequence of the Antarctic Halorubrum lacusprofundi type strain ACAM 34

DOE Office of Scientific and Technical Information (OSTI.GOV)

Anderson, Iain J.; DasSarma, Priya; Lucas, Susan

Halorubrum lacusprofundi is an extreme halophile within the archaeal phylum Euryarchaeota. The type strain ACAM 34 was isolated from Deep Lake, Antarctica. H. lacusprofundi is of phylogenetic interest because it is distantly related to the haloarchaea that have previously been sequenced. It is also of interest because of its psychrotolerance. We report here the complete genome sequence of H. lacusprofundi type strain ACAM 34 and its annotation. In conclusion, this genome is part of a 2006 Joint Genome Institute Community Sequencing Program project to sequence genomes of diverse Archaea.

Management of Breast Sarcoma.

PubMed

Hsu, Cary; McCloskey, Susan A; Peddi, Parvin F

2016-10-01

Breast sarcomas are exceptionally rare mesenchymal neoplasms composed of many histologic subtypes. Therapy is guided by principles established in the management of extremity sarcomas. The anatomic site does influence treatment decisions, particularly the surgical management. Surgery should be undertaken with the aim of achieving a widely negative margin. Selected patients can be managed with breast-conserving surgery. Breast reconstruction is increasingly being undertaken for selected patients. Radiation therapy and chemotherapy are used selectively for large, high-grade sarcomas for which there is significant concern for local and distant recurrence. Copyright © 2016 Elsevier Inc. All rights reserved.

Exploring the Structure of the Distant Universe with MUSE Data Cubes

NASA Astrophysics Data System (ADS)

MacDougall, Mason; Christensen, Lise

2018-01-01

The mass distribution in intergalactic and circumgalactic space is not well known since it is difficult to characterize objects in the distant universe. An ideal tool for studying such distant structure is the Multi-Unit Spectroscopic Explorer (MUSE) of the Very Large Telescope array, which employs a wide field-of-view and a large spectral range to produce high spatial resolution datasets. Here we exploit the 2 spatial dimensions and 1 spectral dimension of a particular MUSE “data cube” to identify and characterize emission line sources near the line-of-sight to quasar PKS1937-101, which lies at a redshift of z=3.787. In particular, we search for galaxy companions to a z=3.572 Lyman-limit system measured in the quasar spectrum and find an associated Lyman-alpha emitter at z=3.556 with a projected distance of 30.2 kpc from the quasar line-of-sight. Through a combination of automated source extraction and manual investigation, we also identify 25 emission line galaxies and 1 other Lyman-alpha emitter in our field. The proximity of several of these objects to the quasar line-of-sight allows us to reliably identify absorption lines in the quasar spectrum that can be associated with observed emission lines with resolved fluxes. This will help characterize the metallicities and kinematics of galaxy halos and circumgalactic media in the early universe.

Galaxy growth in a massive halo in the first billion years of cosmic history

NASA Astrophysics Data System (ADS)

Marrone, D. P.; Spilker, J. S.; Hayward, C. C.; Vieira, J. D.; Aravena, M.; Ashby, M. L. N.; Bayliss, M. B.; Béthermin, M.; Brodwin, M.; Bothwell, M. S.; Carlstrom, J. E.; Chapman, S. C.; Chen, Chian-Chou; Crawford, T. M.; Cunningham, D. J. M.; De Breuck, C.; Fassnacht, C. D.; Gonzalez, A. H.; Greve, T. R.; Hezaveh, Y. D.; Lacaille, K.; Litke, K. C.; Lower, S.; Ma, J.; Malkan, M.; Miller, T. B.; Morningstar, W. R.; Murphy, E. J.; Narayanan, D.; Phadke, K. A.; Rotermund, K. M.; Sreevani, J.; Stalder, B.; Stark, A. A.; Strandet, M. L.; Tang, M.; Weiß, A.

2018-01-01

According to the current understanding of cosmic structure formation, the precursors of the most massive structures in the Universe began to form shortly after the Big Bang, in regions corresponding to the largest fluctuations in the cosmic density field. Observing these structures during their period of active growth and assembly—the first few hundred million years of the Universe—is challenging because it requires surveys that are sensitive enough to detect the distant galaxies that act as signposts for these structures and wide enough to capture the rarest objects. As a result, very few such objects have been detected so far. Here we report observations of a far-infrared-luminous object at redshift 6.900 (less than 800 million years after the Big Bang) that was discovered in a wide-field survey. High-resolution imaging shows it to be a pair of extremely massive star-forming galaxies. The larger is forming stars at a rate of 2,900 solar masses per year, contains 270 billion solar masses of gas and 2.5 billion solar masses of dust, and is more massive than any other known object at a redshift of more than 6. Its rapid star formation is probably triggered by its companion galaxy at a projected separation of 8 kiloparsecs. This merging companion hosts 35 billion solar masses of stars and has a star-formation rate of 540 solar masses per year, but has an order of magnitude less gas and dust than its neighbour and physical conditions akin to those observed in lower-metallicity galaxies in the nearby Universe. These objects suggest the presence of a dark-matter halo with a mass of more than 100 billion solar masses, making it among the rarest dark-matter haloes that should exist in the Universe at this epoch.

Galaxy growth in a massive halo in the first billion years of cosmic history.

PubMed

Marrone, D P; Spilker, J S; Hayward, C C; Vieira, J D; Aravena, M; Ashby, M L N; Bayliss, M B; Béthermin, M; Brodwin, M; Bothwell, M S; Carlstrom, J E; Chapman, S C; Chen, Chian-Chou; Crawford, T M; Cunningham, D J M; De Breuck, C; Fassnacht, C D; Gonzalez, A H; Greve, T R; Hezaveh, Y D; Lacaille, K; Litke, K C; Lower, S; Ma, J; Malkan, M; Miller, T B; Morningstar, W R; Murphy, E J; Narayanan, D; Phadke, K A; Rotermund, K M; Sreevani, J; Stalder, B; Stark, A A; Strandet, M L; Tang, M; Weiß, A

2018-01-04

According to the current understanding of cosmic structure formation, the precursors of the most massive structures in the Universe began to form shortly after the Big Bang, in regions corresponding to the largest fluctuations in the cosmic density field. Observing these structures during their period of active growth and assembly-the first few hundred million years of the Universe-is challenging because it requires surveys that are sensitive enough to detect the distant galaxies that act as signposts for these structures and wide enough to capture the rarest objects. As a result, very few such objects have been detected so far. Here we report observations of a far-infrared-luminous object at redshift 6.900 (less than 800 million years after the Big Bang) that was discovered in a wide-field survey. High-resolution imaging shows it to be a pair of extremely massive star-forming galaxies. The larger is forming stars at a rate of 2,900 solar masses per year, contains 270 billion solar masses of gas and 2.5 billion solar masses of dust, and is more massive than any other known object at a redshift of more than 6. Its rapid star formation is probably triggered by its companion galaxy at a projected separation of 8 kiloparsecs. This merging companion hosts 35 billion solar masses of stars and has a star-formation rate of 540 solar masses per year, but has an order of magnitude less gas and dust than its neighbour and physical conditions akin to those observed in lower-metallicity galaxies in the nearby Universe. These objects suggest the presence of a dark-matter halo with a mass of more than 100 billion solar masses, making it among the rarest dark-matter haloes that should exist in the Universe at this epoch.

Chandra and the VLT Jointly Investigate the Cosmic X-Ray Background

NASA Astrophysics Data System (ADS)

2001-03-01

Summary Important scientific advances often happen when complementary investigational techniques are brought together . In the present case, X-ray and optical/infrared observations with some of the world's foremost telescopes have provided the crucial information needed to solve a 40-year old cosmological riddle. Very detailed observations of a small field in the southern sky have recently been carried out, with the space-based NASA Chandra X-Ray Observatory as well as with several ground-based ESO telescopes, including the Very Large Telescope (VLT) at the Paranal Observatory (Chile). Together, they have provided the "deepest" combined view at X-ray and visual/infrared wavelengths ever obtained into the distant Universe. The concerted observational effort has already yielded significant scientific results. This is primarily due to the possibility to 'identify' most of the X-ray emitting objects detected by the Chandra X-ray Observatory on ground-based optical/infrared images and then to determine their nature and distance by means of detailed (spectral) observations with the VLT . In particular, there is now little doubt that the so-called 'X-ray background' , a seemingly diffuse short-wave radiation first detected in 1962, in fact originates in a vast number of powerful black holes residing in active nuclei of distant galaxies . Moreover, the present investigation has permitted to identify and study in some detail a prime example of a hitherto little known type of object, a distant, so-called 'Type II Quasar' , in which the central black hole is deeply embedded in surrounding gas and dust. These achievements are just the beginning of a most fruitful collaboration between "space" and "ground". It is yet another impressive demonstration of the rapid progress of modern astrophysics, due to the recent emergence of a new generation of extremely powerful instruments. PR Photo 09a/01 : Images of a small part of the Chandra Deep Field South , obtained with ESO telescopes in three different wavebands. PR Photo 09b/01 : A VLT/FORS1 spectrum of a 'Type II Quasar' discovered during this programme. The 'Chandra Deep Field South' and the X-Ray Background ESO PR Photo 09a/01 ESO PR Photo 09a/01 [Preview - JPEG: 400 x 183 pix - 76k] [Normal - JPEG: 800 x 366 pix - 208k] [Hires - JPEG: 3000 x 1453 pix - 1.4M] Caption : PR Photo 09a/01 shows optical/infrared images in three wavebands ('Blue', 'Red', 'Infrared') from ESO telescopes of the Type II Quasar CXOCDFS J033229.9 -275106 (at the centre), one of the distant X-ray sources identified in the Chandra Deep Field South (CDFS) area during the present study. Technical information about these photos is available below. The 'Chandra Deep Field South (CDFS)' is a small sky area in the southern constellation Fornax (The Oven). It measures about 16 arcmin across, or roughly half the diameter of the full moon. There is unusually little gas and dust within the Milky Way in this direction and observations towards the distant Universe within this field thus profit from an particularly clear view. That is exactly why this sky area was selected by an international team of astronomers [1] to carry out an ultra-deep survey of X-ray sources with the orbiting Chandra X-Ray Observatory . In order to detect the faintest possible sources, NASA's satellite telescope looked in this direction during an unprecedented total of almost 1 million seconds of exposure time (11.5 days). The main scientific goal of this survey is to understand the nature and evolution of the elusive sources that make up the 'X-ray background' . This diffuse glare in the X-ray sky was discovered by Riccardo Giacconi and his collaborators during a pioneering rocket experiment in 1962. The excellent imaging quality of Chandra (the angular resolution is about 1 arcsec) makes it possible to do extremely deep exposures without encountering problems introduced by the "confusion effect". This refers to the overlapping of images of sources that are seen close to each other in the sky and thus are difficult to study individually. Previous X-ray satellites were not able to obtain sufficiently sharp X-ray images and the earlier deep X-ray surveys therefore suffered severely from this effect. Moreover, Chandra has much better sensitivity at shorter wavelengths (higher energies) which are less affected by obscuration effects. It can therefore better detect faint sources that emit very energetic ("hard") X-rays. X-ray and optical surveys in the Chandra Deep Field South The one-million second Chandra observations were completed in December 2000. In parallel, a group of astronomers based at institutes in Europe and the USA (the CFDS-team [1]) has been collecting deep images and extensive spectroscopic data with the VLT during the past 2 years (cf. PR Photo 09a/01 ). Their aim was to 'identify' the Chandra X-ray sources, i.e., to unveil their nature and measure their distances. For the identification of these sources, the team has also made extensive use of the observations that were carried out as a part of the comprehensive ESO Imaging Survey Project (EIS). More than 300 X-ray sources were detected in the CDFS by Chandra . A significant fraction of these objects shine so faintly in the optical and near-infrared wavebands that only long-exposure observations with the VLT have been able to detect them. During five observing nights with the FORS1 multi-mode instrument at the 8.2-m VLT ANTU telescope in October and November 2000, the CDFS team was able to identify and obtain spectra of more than one hundred of the X-ray sources registered by Chandra . Nature of the X-ray sources The first results from this study have now confirmed that the 'hard' X-ray background is mainly due to Active Galactic Nuclei (AGN) . The observations also reveal that a large fraction of them are of comparatively low brightness (referred to as 'low-luminosity AGN'), heavily enshrouded by dust and located at distances of 8,000 - 9,000 million light-years (corresponding to a redshift of about 1 and a look-back time of 57% of the age of the Universe [2]) . It is generally believed that all these sources are powered by massive black holes at their centres. Previous X-ray surveys missed most of these objects because they were too faint to be observed by the telescopes then available, in particular at short X-ray wavelengths ('hard X-ray photons') where more radiation from the highly active centres is able to pass through the surrounding, heavily absorbing gas and dust clouds. Other types of well-known X-ray sources, e.g., QSOs ('quasars' = high-luminosity AGN) as well as clusters or groups of galaxies were also detected during these observations. Studies of all classes of objects in the CDFS are also being carried out by several other European groups. This sky field, already a standard reference in the southern hemisphere, will be the subject of several multi-wavelength investigations for many years to come. A prime example will be the Great Observatories Origins Deep Survey (GOODS) which will be carried out by the NASA SIRTF infrared satellite in 2003. Discovery of a distant Type II Quasar ESO PR Photo 09b/01 ESO PR Photo 09b/01 [Preview - JPEG: 400 x 352 pix - 56k] [Normal - JPEG: 800 x 703 pix - 128k] Caption : PR Photo 09b/01 displays the optical spectrum of the distant Type II Quasar CXOCDFS J033229.9 -275106 in the Chandra Deep Field South (CDFS), obtained with the FORS1 multi-mode instrument at VLT ANTU. Strong, redshifted emission lines of Hydrogen and ionised Helium, Oxygen, Nitrogen and Carbon are marked. Technical information about this photo is available below. One particular X-ray source that was identified with the VLT during the present investigation has attracted much attention - it is the discovery of a dust-enshrouded quasar (QSO) at very high redshift ( z = 3.7, corresponding to a distance of about 12,000 million light-years; [2]), cf. PR Photo 09a/01 and PR Photo 09b/01 . It is the first very distant representative of this elusive class of objects (referred to as ' Type II Quasars ') which are believed to account for approximately 90% of the black-hole-powered quasars in the distant Universe. The 'sum' of the identified Chandra X-ray sources in the CDFS was found to match both the intensity and the spectral properties of the observed X-ray background. This important result is a significant step forward towards the definitive resolution of this long-standing cosmological problem. Naturally, ESO astronomer Piero Rosati and his colleagues are thrilled: " It is clearly the combination of the new and detailed Chandra X-ray observations and the enormous light-gathering power of the VLT that has been instrumental to this success. " However, he says, " the identification of the remaining Chandra X-ray sources will be the next challenge for the VLT since they are extremely faint. This is because they are either heavily obscured by dust or because they are extremely distant ". More Information This Press Release is issued simultaneously with a NASA Press Release (see also the Harvard site ). Some of the first results are described in a research paper ("First Results from the X-ray and Optical Survey of the Chandra Deep Field South" available on the web at astro-ph/0007240. More information about science results from the Chandra X-Ray Observatory may be found at: http://asc.harvard.edu/. The optical survey of CDFS at ESO with the Wide-Field Imager is described in connection with PR Photos 46a-b/99 ('100,000 galaxies at a glance'). An image of the Chandra Deep Field South is available at the ESO website on the EIS Image Gallery webpage. . Notes [1]: The Chandra Team is lead by Riccardo Giacconi (Association of Universities Inc. [AUI], Washington, USA) and includes: Piero Rosati , Jacqueline Bergeron , Roberto Gilmozzi , Vincenzo Mainieri , Peter Shaver (European Southern Observatory [ESO]), Paolo Tozzi , Mario Nonino , Stefano Borgani (Osservatorio Astronomico, Trieste, Italy), Guenther Hasinger , Gyula Szokoly (Astrophysical Institute Potsdam [AIP], Germany), Colin Norman , Roberto Gilli , Lisa Kewley , Wei Zheng , Andrew Zirm , JungXian Wang (Johns Hopkins University [JHU], Baltimore, USA), Ken Kellerman (National Radio Astronomy Observatory [NRAO], Charlottesville, USA), Ethan Schreier , Anton Koekemoer and Norman Grogin (Space Telescope Science Institute (STScI), Baltimore, USA). [2] In astronomy, the redshift denotes the fraction by which the lines in the spectrum of an object are shifted towards longer wavelengths. The observed redshift of a distant galaxy or quasar gives a direct estimate of the apparent recession velocity as caused by the universal expansion. Since the expansion rate increases with the distance, the velocity is itself a function (the Hubble relation) of the distance to the object. Redshifts of 1 and 3.7 correspond to when the Universe was about 43% and 12% of its present age. The distances indicated in this Press Release depend on the cosmological model chosen and are based on an age of 19,000 million years. Technical information about the photos PR Photo 09a/01 shows B-, R- and I-band images of a 20 x 20 arcsec 2 area within the CDFS, centred on the Type II Quasar CXOCDFS J033229.9 -275106 . They were obtained with the MPG/ESO 2.2-m telescope and the Wide-Field Imager (WFI) at La Silla (B-band; 8 hrs exposure time) and the 8.2-m VLT ANTU telescope with the FORS1 multi-mode instrument at Paranal (R- and I-bands; each 2 hrs exposure). The measured magnitudes are R=23.5 and I=22.7. The overlaid contours show the associated Chandra X-ray source (smoothed with a sigma = 1 arcsec gaussian profile). North is up and East is left. The spectrum shown in PR Photo 09b/01 was obtained on November 25, 2000, with VLT ANTU and FORS1 in the multislit mode (150-I grism, 1.2 arcsec slit). The exposure time was 3 hours.

Optometric measurements predict performance but not comfort on a virtual object placement task with a stereoscopic three-dimensional display

NASA Astrophysics Data System (ADS)

McIntire, John P.; Wright, Steve T.; Harrington, Lawrence K.; Havig, Paul R.; Watamaniuk, Scott N. J.; Heft, Eric L.

2014-06-01

Twelve participants were tested on a simple virtual object precision placement task while viewing a stereoscopic three-dimensional (S3-D) display. Inclusion criteria included uncorrected or best corrected vision of 20/20 or better in each eye and stereopsis of at least 40 arc sec using the Titmus stereotest. Additionally, binocular function was assessed, including measurements of distant and near phoria (horizontal and vertical) and distant and near horizontal fusion ranges using standard optometric clinical techniques. Before each of six 30 min experimental sessions, measurements of phoria and fusion ranges were repeated using a Keystone View Telebinocular and an S3-D display, respectively. All participants completed experimental sessions in which the task required the precision placement of a virtual object in depth at the same location as a target object. Subjective discomfort was assessed using the simulator sickness questionnaire. Individual placement accuracy in S3-D trials was significantly correlated with several of the binocular screening outcomes: viewers with larger convergent fusion ranges (measured at near distance), larger total fusion ranges (convergent plus divergent ranges, measured at near distance), and/or lower (better) stereoscopic acuity thresholds were more accurate on the placement task. No screening measures were predictive of subjective discomfort, perhaps due to the low levels of discomfort induced.

OBSERVATIONAL SIGNATURES OF A MASSIVE DISTANT PLANET ON THE SCATTERING DISK

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lawler, S. M.; Kavelaars, J. J.; Shankman, C.

The orbital element distribution of trans-Neptunian objects (TNOs) with large pericenters has been suggested to be influenced by the presence of an undetected, large planet at >200 au from the Sun. To find additional observables caused by this scenario, we present here the first detailed emplacement simulation in the presence of a massive ninth planet on the distant Kuiper Belt. We perform 4 Gyr N -body simulations with the currently known solar system planetary architecture, plus a 10  M {sub ⊕} planet with similar orbital parameters to those suggested by Trujillo and Sheppard or Batygin and Brown, and 10{sup 5} testmore » particles in an initial planetesimal disk. We find that including a distant super-Earth-mass planet produces a substantially different orbital distribution for the scattering and detached TNOs, raising the pericenters and inclinations of moderate semimajor axis (50 <  a  < 500 au) objects. We test whether this signature is detectable via a simulator with the observational characteristics of four precisely characterized TNO surveys. We find that the qualitatively very distinct solar system models that include a ninth planet are essentially observationally indistinguishable from an outer solar system produced solely by the four giant planets. We also find that the mass of the Kuiper Belt’s current scattering and detached populations is required to be 3–10 times larger in the presence of an additional planet. We do not find any evidence for clustering of orbital angles in our simulated TNO population. Wide-field, deep surveys targeting inclined high-pericenter objects will be required to distinguish between these different scenarios.« less

Improving Predictions and Management of Hydrological Extremes through Climate Services

NASA Astrophysics Data System (ADS)

van den Hurk, Bart; Wijngaard, Janet; Pappenberger, Florian; Bouwer, Laurens; Weerts, Albrecht; Buontempo, Carlo; Doescher, Ralf; Manez, Maria; Ramos, Maria-Helena; Hananel, Cedric; Ercin, Ertug; Hunink, Johannes; Klein, Bastian; Pouget, Laurent; Ward, Philip

2016-04-01

The EU Roadmap on Climate Services can be seen as a result of convergence between the society's call for "actionable research", and the climate research community providing tailored data, information and knowledge. However, although weather and climate have clearly distinct definitions, a strong link between weather and climate services exists that is not explored extensively. Stakeholders being interviewed in the context of the Roadmap consider climate as a far distant long term feature that is difficult to consider in present-day decision taking, which is dominated by daily experience with handling extreme events. It is argued that this experience is a rich source of inspiration to increase society's resilience to an unknown future. A newly started European research project, IMPREX, is built on the notion that "experience in managing current day weather extremes is the best learning school to anticipate consequences of future climate". This paper illustrates possible ways to increase the link between information and services addressing weather and climate time scales by discussing the underlying concepts of IMPREX and its expected outcome.

Referrals for pediatric weight management: the importance of proximity.

PubMed

Ambler, Kathryn A; Hagedorn, Douglas W J; Ball, Geoff D C

2010-11-01

Limited access to weight management care can have a negative impact on the health and well-being of obese children and youth. Our objectives were to describe the characteristics of clients referred to a pediatric weight management centre and explore potential differences according to proximity. All demographic and anthropometric data were abstracted from standardized, one-page referral forms, which were received by a pediatric weight management centre in Edmonton, AB (Canada) between April, 2005 and April, 2009. Referrals (n = 555; 52% male; age [mean +/- standard deviation]: 12.4 +/- 2.6 y; BMI: 32.3 +/- 6.8 kg/m2; BMI percentile: 98.4 +/- 1.7; BMI z-score: 2.3 +/- 0.4) were received from 311 physicians. Approximately 95% of referrals were for boys and girls classified as obese or very obese. Based on postal code data, individuals were dichotomized as either living within (local; n = 455) or beyond (distant; n = 100) the Edmonton Census Metropolitan Area. Numerous families resided several hundred kilometres away from our centre. Overall, distant clients were taller, weighed more, and were more overweight than their local counterparts. For distant clients, the degree of overweight was higher in youth versus children. Pediatric weight management services must be designed to optimize access to health services, especially for distant clients who may be at increased obesity-related health risk.

James Webb Space Telescope (JWST) and Star Formation

NASA Technical Reports Server (NTRS)

Greene, Thomas P.

2010-01-01

The 6.5-m aperture James Webb Space Telescope (JWST) will be a powerful tool for studying and advancing numerous areas of astrophysics. Its Fine Guidance Sensor, Near-Infrared Camera, Near-Infrared Spectrograph, and Mid-Infrared Instrument will be capable of making very sensitive, high angular resolution imaging and spectroscopic observations spanning 0.7 - 28 ?m wavelength. These capabilities are very well suited for probing the conditions of star formation in the distant and local Universe. Indeed, JWST has been designed to detect first light objects as well as to study the fine details of jets, disks, chemistry, envelopes, and the central cores of nearby protostars. We will be able to use its cameras, coronagraphs, and spectrographs (including multi-object and integral field capabilities) to study many aspects of star forming regions throughout the galaxy, the Local Group, and more distant regions. I will describe the basic JWST scientific capabilities and illustrate a few ways how they can be applied to star formation issues and conditions with a focus on Galactic regions.

Biofeedback for Better Vision

NASA Technical Reports Server (NTRS)

1990-01-01

Biofeedtrac, Inc.'s Accommotrac Vision Trainer, invented by Dr. Joseph Trachtman, is based on vision research performed by Ames Research Center and a special optometer developed for the Ames program by Stanford Research Institute. In the United States, about 150 million people are myopes (nearsighted), who tend to overfocus when they look at distant objects causing blurry distant vision, or hyperopes (farsighted), whose vision blurs when they look at close objects because they tend to underfocus. The Accommotrac system is an optical/electronic system used by a doctor as an aid in teaching a patient how to contract and relax the ciliary body, the focusing muscle. The key is biofeedback, wherein the patient learns to control a bodily process or function he is not normally aware of. Trachtman claims a 90 percent success rate for correcting, improving or stopping focusing problems. The Vision Trainer has also proved effective in treating other eye problems such as eye oscillation, cross eyes, and lazy eye and in professional sports to improve athletes' peripheral vision and reaction time.

Development of using experimenter-given cues in infant chimpanzees: longitudinal changes in behavior and cognitive development.

PubMed

Okamoto-Barth, Sanae; Tomonaga, Masaki; Tanaka, Masayuki; Matsuzawa, Tetsuro

2008-01-01

The use of gaze shifts as social cues has various evolutionary advantages. To investigate the developmental processes of this ability, we conducted an object-choice task by using longitudinal methods with infant chimpanzees tested from 8 months old until 3 years old. The experimenter used one of six gestures towards a cup concealing food; tapping, touching, whole-hand pointing, gazing plus close-pointing, distant-pointing, close-gazing, and distant-gazing. Unlike any other previous study, we analyzed the behavioral changes that occurred before and after choosing the cup. We assumed that pre-choice behavior indicates the development of an attentional and spatial connection between a pointing cue and an object (e.g. Woodward, 2005); and post-choice behavior indicates the emergence of object permanence (e.g. Piaget, 1954). Our study demonstrated that infant chimpanzees begin to use experimenter-given cues with age (after 11 months of age). Moreover, the results from the behavioral analysis showed that the infants gradually developed the spatial link between the pointing as an object-directed action and the object. Moreover, when they were 11 months old, the infants began to inspect the inside of the cup, suggesting the onset of object permanence. Overall, our results imply that the ability to use the cues is developing and mutually related with other cognitive developments. The present study also suggests what the standard object-choice task actually measures by breaking the task down into the developmental trajectories of its component parts, and describes for the first time the social-physical cognitive development during the task with a longitudinal method.

Distant Migration of Multiple Siliconomas in Lower Extremities following Breast Implant Rupture: Case Report.

PubMed

Oh, Joo Hyun; Song, Seung Yong; Lew, Dae Hyun; Lee, Dong Won

2016-10-01

Siliconoma from ruptured breast implants has been reported in multiple body sites, including but not limited to the breast parenchyma, axillary lymph nodes, upper arm, and even lower leg. In this regard, we report a rare case of distant silicone migration to the lower extremities after traumatic breast implant rupture. A 55-year-old Asian woman who received bilateral augmentation mammoplasty 20 years ago presented with ruptured breast implants from a car accident 2 years earlier. Magnetic resonance imaging confirmed intracapsular and extracapsular rupture of the right breast implant, showing "linguine sign." We removed the bilateral breast implants and performed capsulectomy and bilateral reduction mammoplasty using inverted-T incisions. The implant was confirmed as a smooth, silicone gel-filled mammary implant of 125 cm 3 by a Japanese manufacturer, Koken. During her regular follow-up outpatient visits, physical examination revealed 2.5- × 1.5-cm ill-defined, tender, subcutaneous nodules on both knees and 8.5- × 3.0-cm inflammatory changes in the inguinal area with persistent pain. Computed tomography showed no definite mass, but rather infiltrative, nonenhancing soft-tissue densities in the subcutaneous layers of the bilateral inguinal and knee areas. Surgical excision was performed, and pathologic findings confirmed variable vacuoles with foreign body reaction and fibrosis, consistent with siliconoma. It is important to acknowledge that siliconomas can be encountered in patients with ruptured breast implants, especially those manufactured decades ago. Our patient with masses as remote as the inguinal and knee areas is a prime example of how far siliconomas can migrate.

Distant Migration of Multiple Siliconomas in Lower Extremities following Breast Implant Rupture: Case Report

PubMed Central

Oh, Joo Hyun; Song, Seung Yong; Lew, Dae Hyun

2016-01-01

Summary: Siliconoma from ruptured breast implants has been reported in multiple body sites, including but not limited to the breast parenchyma, axillary lymph nodes, upper arm, and even lower leg. In this regard, we report a rare case of distant silicone migration to the lower extremities after traumatic breast implant rupture. A 55-year-old Asian woman who received bilateral augmentation mammoplasty 20 years ago presented with ruptured breast implants from a car accident 2 years earlier. Magnetic resonance imaging confirmed intracapsular and extracapsular rupture of the right breast implant, showing “linguine sign.” We removed the bilateral breast implants and performed capsulectomy and bilateral reduction mammoplasty using inverted-T incisions. The implant was confirmed as a smooth, silicone gel–filled mammary implant of 125 cm3 by a Japanese manufacturer, Koken. During her regular follow-up outpatient visits, physical examination revealed 2.5- × 1.5-cm ill-defined, tender, subcutaneous nodules on both knees and 8.5- × 3.0-cm inflammatory changes in the inguinal area with persistent pain. Computed tomography showed no definite mass, but rather infiltrative, nonenhancing soft-tissue densities in the subcutaneous layers of the bilateral inguinal and knee areas. Surgical excision was performed, and pathologic findings confirmed variable vacuoles with foreign body reaction and fibrosis, consistent with siliconoma. It is important to acknowledge that siliconomas can be encountered in patients with ruptured breast implants, especially those manufactured decades ago. Our patient with masses as remote as the inguinal and knee areas is a prime example of how far siliconomas can migrate. PMID:27826457

The most distant, luminous, dusty star-forming galaxies: redshifts from NOEMA and ALMA spectral scans

NASA Astrophysics Data System (ADS)

Fudamoto, Y.; Ivison, R. J.; Oteo, I.; Krips, M.; Zhang, Z.-Y.; Weiss, A.; Dannerbauer, H.; Omont, A.; Chapman, S. C.; Christensen, L.; Arumugam, V.; Bertoldi, F.; Bremer, M.; Clements, D. L.; Dunne, L.; Eales, S. A.; Greenslade, J.; Maddox, S.; Martinez-Navajas, P.; Michalowski, M.; Pérez-Fournon, I.; Riechers, D.; Simpson, J. M.; Stalder, B.; Valiante, E.; van der Werf, P.

2017-12-01

We present 1.3- and/or 3-mm continuum images and 3-mm spectral scans, obtained using Northern Extended Millimeter Array (NOEMA) and Atacama Large Millimeter Array (ALMA), of 21 distant, dusty, star-forming galaxies. Our sample is a subset of the galaxies selected by Ivison et al. on the basis of their extremely red far-infrared (far-IR) colours and low Herschel flux densities; most are thus expected to be unlensed, extraordinarily luminous starbursts at z ≳ 4, modulo the considerable cross-section to gravitational lensing implied by their redshift. We observed 17 of these galaxies with NOEMA and four with ALMA, scanning through the 3-mm atmospheric window. We have obtained secure redshifts for seven galaxies via detection of multiple CO lines, one of them a lensed system at z = 6.027 (two others are also found to be lensed); a single emission line was detected in another four galaxies, one of which has been shown elsewhere to lie at z = 4.002. Where we find no spectroscopic redshifts, the galaxies are generally less luminous by 0.3-0.4 dex, which goes some way to explaining our failure to detect line emission. We show that this sample contains the most luminous known star-forming galaxies. Due to their extreme star-formation activity, these galaxies will consume their molecular gas in ≲ 100 Myr, despite their high molecular gas masses, and are therefore plausible progenitors of the massive, 'red-and-dead' elliptical galaxies at z ≈ 3.

Patient data system for monitoring shunts.

PubMed

Frank, E; Su, E; Smith, K

1988-01-01

Rapidly locating accurate data on a patient's shunt system is often extremely difficult. We have developed a simple system to fill a perceived need for recording current data on a patients shunt. This system employs an easily updated record in the patient's hospital or clinic chart as well as a wallet-sized data card for the patient or his family to carry. The data in the chart include the configuration of the patient's current shunt system and a graphic record of previous shunt problems. The small patient data card describes the age of the shunt system and its current configuration. We have found that this system provides assistance in the routine follow-up of patients with shunts and plays an extremely necessary role in the emergency evaluation of these patients, particularly when an emergency evaluation is undertaken in facilities distant from the location of regular treatment.

A complex multi-notch astronomical filter to suppress the bright infrared sky.

PubMed

Bland-Hawthorn, J; Ellis, S C; Leon-Saval, S G; Haynes, R; Roth, M M; Löhmannsröben, H-G; Horton, A J; Cuby, J-G; Birks, T A; Lawrence, J S; Gillingham, P; Ryder, S D; Trinh, C

2011-12-06

A long-standing and profound problem in astronomy is the difficulty in obtaining deep near-infrared observations due to the extreme brightness and variability of the night sky at these wavelengths. A solution to this problem is crucial if we are to obtain the deepest possible observations of the early Universe, as redshifted starlight from distant galaxies appears at these wavelengths. The atmospheric emission between 1,000 and 1,800 nm arises almost entirely from a forest of extremely bright, very narrow hydroxyl emission lines that varies on timescales of minutes. The astronomical community has long envisaged the prospect of selectively removing these lines, while retaining high throughput between them. Here we demonstrate such a filter for the first time, presenting results from the first on-sky tests. Its use on current 8 m telescopes and future 30 m telescopes will open up many new research avenues in the years to come.

New Opportunities for Outer Solar System Science using Radioisotope Electric Propulsion

DOE Office of Scientific and Technical Information (OSTI.GOV)

Noble, Robert J.; /SLAC; Amini, Rashied

Today, our questions and hypotheses about the Solar System's origin have surpassed our ability to deliver scientific instruments to deep space. The moons of the outer planets, the Trojan and Centaur minor planets, the trans-Neptunian objects (TNO), and distant Kuiper Belt objects (KBO) hold a wealth of information about the primordial conditions that led to the formation of our Solar System. Robotic missions to these objects are needed to make the discoveries, but the lack of deep-space propulsion is impeding this science. Radioisotope electric propulsion (REP) will revolutionize the way we do deep-space planetary science with robotic vehicles, giving themmore » unprecedented mobility. Radioisotope electric generators and lightweight ion thrusters are being developed today which will make possible REP systems with specific power in the range of 5 to 10 W/kg. Studies have shown that this specific power range is sufficient to perform fast rendezvous missions from Earth to the outer Solar System and fast sample return missions. This whitepaper discusses how mobility provided by REP opens up entirely new science opportunities for robotic missions to distant primitive bodies. We also give an overview of REP technology developments and the required next steps to realize REP.« less

Switchable electro-optic diffractive lens with high efficiency for ophthalmic applications

PubMed Central

Li, Guoqiang; Mathine, David L.; Valley, Pouria; Äyräs, Pekka; Haddock, Joshua N.; Giridhar, M. S.; Williby, Gregory; Schwiegerling, Jim; Meredith, Gerald R.; Kippelen, Bernard; Honkanen, Seppo; Peyghambarian, Nasser

2006-01-01

Presbyopia is an age-related loss of accommodation of the human eye that manifests itself as inability to shift focus from distant to near objects. Assuming no refractive error, presbyopes have clear vision of distant objects; they require reading glasses for viewing near objects. Area-divided bifocal lenses are one example of a treatment for this problem. However, the field of view is limited in such eyeglasses, requiring the user to gaze down to accomplish near-vision tasks and in some cases causing dizziness and discomfort. Here, we report on previously undescribed switchable, flat, liquid-crystal diffractive lenses that can adaptively change their focusing power. The operation of these spectacle lenses is based on electrical control of the refractive index of a 5-μm-thick layer of nematic liquid crystal using a circular array of photolithographically defined transparent electrodes. It operates with high transmission, low voltage (<2 Vrms), fast response (<1 sec), diffraction efficiency > 90%, small aberrations, and a power-failure-safe configuration. These results represent significant advance in state-of-the-art liquid-crystal diffractive lenses for vision care and other applications. They have the potential of revolutionizing the field of presbyopia correction when combined with automatic adjustable focusing power. PMID:16597675

Spatiotemporal distribution of location and object effects in the electromyographic activity of upper extremity muscles during reach-to-grasp

PubMed Central

Rouse, Adam G.

2016-01-01

In reaching to grasp an object, proximal muscles that act on the shoulder and elbow classically have been viewed as transporting the hand to the intended location, while distal muscles that act on the fingers simultaneously shape the hand to grasp the object. Prior studies of electromyographic (EMG) activity in upper extremity muscles therefore have focused, by and large, either on proximal muscle activity during reaching to different locations or on distal muscle activity as the subject grasps various objects. Here, we examined the EMG activity of muscles from the shoulder to the hand, as monkeys reached and grasped in a task that dissociated location and object. We quantified the extent to which variation in the EMG activity of each muscle depended on location, on object, and on their interaction—all as a function of time. Although EMG variation depended on both location and object beginning early in the movement, an early phase of substantial location effects in muscles from proximal to distal was followed by a later phase in which object effects predominated throughout the extremity. Interaction effects remained relatively small. Our findings indicate that neural control of reach-to-grasp may occur largely in two sequential phases: the first, serving to project the entire upper extremity toward the intended location, and the second, acting predominantly to shape the entire extremity for grasping the object. PMID:27009156

Oxidative stress may be involved in distant organ failure in tourniquet shock model mice.

PubMed

Nishikata, Rie; Kato, Naho; Hiraiwa, Kouichi

2014-03-01

Crush syndrome is characterized by prolonged shock resulting from extensive muscle damage and multiple organ failure. However, the pathogenesis of multiple organ failure has not yet been completely elucidated. Therefore, we investigated the molecular biological and histopathological aspects of distant organ injury in crush syndrome by using tourniquet shock model mice. DNA microarray analysis of the soleus muscle showed an increase in the mRNA levels of Cox-2, Hsp70, c-fos, and IL-6, at 3h after ischemia/reperfusion injury at the lower extremity. In vivo staining with hematoxylin and eosin (HE) showed edema and degeneration in the soleus muscle, but no change in the distant organs. Immunohistological staining of the HSP70 protein revealed nuclear translocation in the soleus muscle, kidney, liver, and lung. The c-fos mRNA levels were elevated in the soleus muscle, kidney, and liver, displaying nuclear translocation of c-FOS protein. Terminal deoxynucleotidyl transferase dUTP nick-end labeling (TUNEL) analysis suggested the involvement of apoptosis in ischemia/reperfusion injury in the soleus muscle. Apoptotic cells were not found in greater quantities in the kidney. Oxidative stress, as determined using a free radical elective evaluator (d-ROM test), markedly increased after ischemia/reperfusion injury. Therefore, examination of immunohistological changes and determination of oxidative stress are proposed to be useful in evaluating the extent of tourniquet shock, even before changes are observed by HE staining. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

TEMPLATES: Targeting Extremely Magnified Panchromatic Lensed Arcs and Their Extended Star Formation

NASA Astrophysics Data System (ADS)

Rigby, Jane; Vieira, Joaquin; Bayliss, M.; Fischer, T.; Florian, M.; Gladders, M.; Gonzalez, A.; Law, D.; Marrone, D.; Phadke, K.; Sharon, K.; Spilker, J.

2017-11-01

We propose high signal-to-noise NIRSpec and MIRI IFU spectroscopy, with accompanying imaging, for 4 gravitationally lensed galaxies at 1

Patient with Gorlin syndrome and metastatic basal cell carcinoma refractory to smoothened inhibitors.

PubMed

Zhu, Gefei A; Li, Angela S; Chang, Anne Lynn S

2014-08-01

Basal cell carcinomas (BCCs) in patients with Gorlin syndrome have been reported to be extremely sensitive to Smoothened (SMO) inhibitors, a novel targeted therapy against the Hedgehog pathway, because of characteristic mutations in these patients. A few cases of disease refractory to oral therapy with SMO inhibitors have been reported in patients with Gorlin syndrome and nonmetastatic BCCs, but refractory disease in distantly metastatic tumors has not been documented in this high-risk group. A man with Gorlin syndrome and innumerable cutaneous BCCs presented with biopsy-proven BCC in his lungs. After SMO inhibitor therapy, almost all of his cutaneous tumors shrank, but his lung metastases did not. These lung metastases remained refractory to treatment despite institution of a second SMO inhibitor. We report a case of Gorlin syndrome in a patient with metastatic BCC refractory to SMO inhibitors. Furthermore, clinical responses in this patient's cutaneous tumors did not parallel the responses in the distant site. However, serial imaging after diagnosis of metastatic disease can be critical to monitor for response to therapy.

Long-term allergic dermatitis caused by sevoflurane: a clinical report.

PubMed

Lloréns Herrerias, J; Delgado Navarro, C; Ballester Luján, M T; Izquierdo Palomares, A

2014-10-01

Allergy to volatile anaesthetics is extremely rare, but capable of damaging the professional career. This article presents the case of a 60-year-old surgeon who developed a skin rash on the reverse of hands, which progressively worsened and extended to distant fold areas. Blood tests were normal but for eosinophilia and risen total IgE, with normal specific globulins and skin prick tests for common allergens. After 8 years, a malfunction in the anaesthetic gas scavenging system was found, and symptoms remitted within a week following its replacement. Repeated open application test with sevoflurane led to the appearance of the same lesions in the tested areas and in distant body folds. We hypothesize that the most probable mechanism for the reaction in our patient is systemic allergic contact dermatitis, which is caused by repeated systemic exposure to a hapten that reaches the skin through haematogenous transport in a sensitized patient. The report aims to warn about the potential aetiological relationship between exposure to inhaled anaesthetics and allergic manifestations with cutaneous symptoms. © 2014 The Acta Anaesthesiologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

KSC-03PD-2681

NASA Technical Reports Server (NTRS)

2003-01-01

KENNEDY SPACE CENTER, FLA. This storyboard shows a diagram of the telescope design and photos for a new five-meter focal length scope. The tracking telescope is part of the Distant Object Attitude Measurement System (DOAMS) in Cocoa Beach, Fla., that provides optical support for launches from KSC and Cape Canaveral.

Extreme Trust Region Policy Optimization for Active Object Recognition.

PubMed

Liu, Huaping; Wu, Yupei; Sun, Fuchun; Huaping Liu; Yupei Wu; Fuchun Sun; Sun, Fuchun; Liu, Huaping; Wu, Yupei

2018-06-01

In this brief, we develop a deep reinforcement learning method to actively recognize objects by choosing a sequence of actions for an active camera that helps to discriminate between the objects. The method is realized using trust region policy optimization, in which the policy is realized by an extreme learning machine and, therefore, leads to efficient optimization algorithm. The experimental results on the publicly available data set show the advantages of the developed extreme trust region optimization method.

Discovery of prognostic biomarkers for predicting lung cancer metastasis using microarray and survival data.

PubMed

Huang, Hui-Ling; Wu, Yu-Chung; Su, Li-Jen; Huang, Yun-Ju; Charoenkwan, Phasit; Chen, Wen-Liang; Lee, Hua-Chin; Chu, William Cheng-Chung; Ho, Shinn-Ying

2015-02-21

Few studies have investigated prognostic biomarkers of distant metastases of lung cancer. One of the central difficulties in identifying biomarkers from microarray data is the availability of only a small number of samples, which results overtraining. Recently obtained evidence reveals that epithelial-mesenchymal transition (EMT) of tumor cells causes metastasis, which is detrimental to patients' survival. This work proposes a novel optimization approach to discovering EMT-related prognostic biomarkers to predict the distant metastasis of lung cancer using both microarray and survival data. This weighted objective function maximizes both the accuracy of prediction of distant metastasis and the area between the disease-free survival curves of the non-distant and distant metastases. Seventy-eight patients with lung cancer and a follow-up time of 120 months are used to identify a set of gene markers and an independent cohort of 26 patients is used to evaluate the identified biomarkers. The medical records of the 78 patients show a significant difference between the disease-free survival times of the 37 non-distant- and the 41 distant-metastasis patients. The experimental results thus obtained are as follows. 1) The use of disease-free survival curves can compensate for the shortcoming of insufficient samples and greatly increase the test accuracy by 11.10%; and 2) the support vector machine with a set of 17 transcripts, such as CCL16 and CDKN2AIP, can yield a leave-one-out cross-validation accuracy of 93.59%, a test accuracy of 76.92%, a large disease-free survival area of 74.81%, and a mean survival prediction error of 3.99 months. The identified putative biomarkers are examined using related studies and signaling pathways to reveal the potential effectiveness of the biomarkers in prospective confirmatory studies. The proposed new optimization approach to identifying prognostic biomarkers by combining multiple sources of data (microarray and survival) can facilitate the accurate selection of biomarkers that are most relevant to the disease while solving the problem of insufficient samples.

The Human Vertical Translation Vestibulo-ocular Reflex (tVOR): Normal and Abnormal Responses

PubMed Central

Liao, Ke; Walker, Mark F.; Joshi, Anand; Reschke, Millard; Strupp, Michael; Leigh, R. John

2010-01-01

Geometric considerations indicate that the human translational vestibulo-ocular reflex (tVOR) should have substantially different properties than the angular vestibulo-ocular reflex (aVOR). Specifically, tVOR cannot simultaneously stabilize images of distant and near objects on the retina. Most studies make the tacit assumption that tVOR acts to stabilize foveal images even though, in humans, tVOR is reported to compensate for less than 60% of foveal image motion. We have determined that the compensation gain (eye rotational velocity / required eye rotational velocity to maintain foveal target fixation) of tVOR is held steady at ~ 0.6 during viewing of either near or distant targets during vertical (bob) translations in ambient illumination. We postulate that tVOR evolved not to stabilize the image of the target on the fovea, but rather to minimize retinal image motion between objects lying in different depth planes, in order to optimize motion parallax information. Such behavior is optimized when binocular visual cues of both far and distant targets are available in ambient light. Patients with progressive supranuclear palsy or cerebellar ataxia show impaired ability to increase tVOR responses appropriately when they view near targets. In cerebellar patients, impaired ability to adjust tVOR responses to viewing conditions occurs despite intact ability to converge at near. Loss of the ability to adjust tVOR according to viewing conditions appears to represent a distinct disorder of vestibular function. PMID:19645882

Waiting for Shadows from the Distant Solar System

NASA Astrophysics Data System (ADS)

Kohler, Susanna

2016-03-01

How can we hope to measure the hundreds of thousands of objects in our distant solar system? A team of astronomers is harnessing citizen science to begin to tackle this problem!A light curve from an occultation collected by a RECON site in Quincy, California. As the objects shadow passes, the background stars light dims. [RECON/Charley Arrowsmith (Feather River College)]Occultation InformationEstimates currently place the number of Kuiper belt objects larger than 100 km across at over 100,000. Knowing the sizes and characteristics of these objects is important for understanding the composition of the outer solar system and constraining models of the solar systems formation and evolution.Unfortunately, measuring small, dim bodies at large distances is incredibly difficult! One of the best ways to obtain the sizes of these objects is to watch as they occult a distant star. Timing the object as it passes across the face of the star can give us a good measure of its size and shape, when observed from multiple stations in the path of the shadow.An Extended NetworkOccultations by nearby objects (like main-belt asteroids) can be predicted fairly accurately, but those by trans-Neptunian objects are much more poorly constrained. Only ~900 trans-Neptunian objects have approximately known paths, and occultation-shadow predictions for these objects are often only accurate to ~1000km on the Earths surface. So how can we ensure that theres a telescope in the right location, ready to observe when an occultation occurs?Map of the 56 RECON sites distributed over 2000 km in the western United States. [Buie et al. 2016]The simplest answer is to set up a huge network of observing stations, and wait for the shadows to come to the network. With this approach, even if the predicted path isnt precisely known, some of the stations will still observe the occultation.Due to the number of stations needed, this project lends itself perfectly to citizen science. In a recently published paper by Marc Buie (Southwest Research Institute) and John Keller (California Polytechnic State University), the team describes the Research and Education Collaborative Occultation Network (RECON).RECON of Distant ObjectsRECON consists of 56 communities in the western United States that have each been armed with a telescope, camera, and timing device. The observing groups include teachers and their students, amateur astronomers, and other community members, and telescopes are primarily located at schools.Because the shadows from occultations generally travel from east to west, the communities are based in a roughly north-south network spanning 2000 km. Theyre spaced no more than 50 km apart, providing enough coverage to obtain sizes for 100-km objects crossing the baseline.RECON is a great example of how citizen science can be used to advance astronomy. The project reached full operating status in April 2015, and it has already conducted two official observing campaigns of trans-Neptunian objects, as well as roughly 30 additional campaigns, including training runs and local projects. The team is now publishing some of its first results in an upcoming paper, so keep an eye out for future publications to find out what theyve learned!BonusCheck out this awesome video of an asteroid occulting a star, as observed by a RECON system. The grey field shows the actual video image collected by one of the RECON cameras, in which one of the two visible stars (the one on the right) is occulted. The asteroid itself is too dim for us to see. The inset at the top left shows the light curve collected during the occultation, and the upper right-hand corner shows an animation of the asteroid as it occults the star. [RECON]CitationMarc W. Buie and John M. Keller 2016 AJ 151 73. doi:10.3847/0004-6256/151/3/73

Magnetic field reconnection. [energy conversion in space plasma

NASA Technical Reports Server (NTRS)

Sonnerup, U. O.

1979-01-01

A reasonably detailed description is obtained of the current status of our understanding of magnetic field reconnection. The picture that emerges is of a process, simple in concept but extremely complicated and multifaceted in detail. Nonlinear MHD processes in the external flow region, governed by distant boundary conditions, are coupled to nonlinear microscopic plasma processes in the diffusion region, in a manner not clearly understood. It appears that reconnection may operate in entirely different ways for different plasma parameters and different external boundary conditions. Steady reconnection may be allowed in some cases, forbidden in others, with intermediate situations involving impulsive or pulsative events.

Merkel Cell Carcinoma Metastatic to Pleural Fluid: A Case Report.

PubMed

Rhee, Ye-Young; Kim, Soo Hee; Kim, Eun Kyung; Kim, Se Hoon

2018-05-01

Merkel cell carcinoma (MCC) is a rare aggressive neuroendocrine carcinoma of the skin that shows locoregional or distant metastasis. Metastasis of MCC to body cavity effusion is extremely rare; only three cases have been reported so far. Metastatic MCC in effusion cytology shows small blue round cells with fine stippled chromatin like other small blue round cell tumors such as small cell lung carcinoma or lymphoma. The diagnosis of metastatic MCC can grant patients good chances at recently advanced therapeutic options. Here, we present a case of metastatic MCC to pleural effusion with characteristic single file-like pattern.

Galaxy evolution in clusters since z~1

NASA Astrophysics Data System (ADS)

Aragon-Salamanca, Alfonso

2010-09-01

Galaxy clusters provide some of the most extreme environments in which galaxies evolve, making them excellent laboratories to study the age old question of "nature" vs. "nurture" in galaxy evolution. Here I review some of the key observational results obtained during the last decade on the evolution of the morphology, structure, dynamics, star-formation history and stellar populations of cluster galaxies since the time when the universe was half its present age. Many of the results presented here have been obtained within the ESO Distant Cluster Survey (EDisCS) and Space Telescope A901/02 Galaxy Evolution Survey (STAGES) collaborations.

Galaxy Evolution in Clusters Since z ~ 1

NASA Astrophysics Data System (ADS)

Aragón-Salamanca, A.

Galaxy clusters provide some of the most extreme environments in which galaxies evolve, making them excellent laboratories to study the age old question of "nature" vs. "nurture" in galaxy evolution. Here I review some of the key observational results obtained during the last decade on the evolution of the morphology, structure, dynamics, star-formation history and stellar populations of cluster galaxies since the time when the Universe was half its present age. Many of the results presented here have been obtained within the ESO Distant Cluster Survey (EDisCS) and Space Telescope A901/02 Galaxy Evolution Survey (STAGES) collaborations.

A Randomized Controlled Trial of Tong Len Meditation Practice in Cancer Patients: Evaluation of a Distant Psychological Healing Effect.

PubMed

Pagliaro, Gioacchino; Pandolfi, Paolo; Collina, Natalina; Frezza, Giovanni; Brandes, Alba; Galli, Margherita; Avventuroso, Federica Marzocchi; De Lisio, Sara; Musti, Muriel Assunta; Franceschi, Enrico; Esposti, Roberta Degli; Lombardo, Laura; Cavallo, Giovanna; Di Battista, Monica; Rimondini, Simonetta; Poggi, Rosalba; Susini, Cinzia; Renzi, Rina; Marconi, Linda

2016-01-01

Tong Len meditation is an important therapeutic tool in the Tibetan medicine, and it can be used for self-healing and/or to heal others. Currently, in the West, there is no scientific study concerning the efficacy of a Tong Len distant healing effect on psychological disorders in cancer patients. To evaluate a distant healing effect of Tong Len meditation on stress, anxiety, depression, fatigue, and self-perceived quality of life in cancer patients. These psychological objectives were chosen as a consequence of the limited scientific literature of present day. We performed a double-blind randomized controlled trial on 103 cancer patients with tumors. Overall, 12 meditators used Tong Len in aid of 52 patients randomly selected as experimental group, while the remaining 51 patients constituted the control group. Patients and meditators did not know each other. All patients completed profile of mood states (POMS) and European Quality of Life-5 dimensions (EQ-5D) questionnaires before treatment (T0), after two (T1) and three months of treatment (T2), and one month after treatment cessation (T3). With regard to the parameters related to depression, a statistically significant improvement (P = .003) was observed in the treatment group compared to controls. On the other hand, the vigor/activity parameter saw significant improvements in the control group (P = .009). Both groups exhibited significant improvements in the other factors assessed in the POMS and EQ-5D questionnaires. This study did not provide sufficient evidence supporting an efficacy of Tong Len meditation in distant psychological healing as compared to a control condition. The research highlighted some psychological improvements through Tong Len distant meditation in a group of patients unknown to meditators. Therefore, the enhancement detected in most parameters in both treatment and control groups raises interest on in-depth analysis and evaluation of distant meditation on cancer patients to mitigate psychological problems caused by the disease. Copyright © 2016 Elsevier Inc. All rights reserved.

Misconceptions about an Expanding Universe

DOE Office of Scientific and Technical Information (OSTI.GOV)

Samuel, Stuart; /SLAC /LBL, Berkeley

2005-12-14

Various results are obtained for a Friedmann-Robertson-Walker cosmology. We derive an exact equation that determines Hubble's law, clarify issues concerning the speeds of faraway objects and uncover a ''tail-light angle effect'' for distant luminous sources. The latter leads to a small, previously unnoticed correction to the parallax distance formula.

Geometric Determinants of Human Spatial Memory

ERIC Educational Resources Information Center

Hartley, Tom; Trinkler, Iris; Burgess, Neil

2004-01-01

Geometric alterations to the boundaries of a virtual environment were used to investigate the representations underlying human spatial memory. Subjects encountered a cue object in a simple rectangular enclosure, with distant landmarks for orientation. After a brief delay, during which they were removed from the arena, subjects were returned to it…

15 CFR 2301.4 - Types of projects and broadcast priorities.

Code of Federal Regulations, 2014 CFR

2014-01-01

... the objectives set forth at 47 U.S.C. 393(b), the Agency has developed the following categories. Each... nonbroadcast projects offering educational or instructional services). (b) Broadcast applications. The... telecommunications signal is distant when the geographical area to which the source is brought is beyond the grade B...

15 CFR 2301.4 - Types of projects and broadcast priorities.

Code of Federal Regulations, 2011 CFR

2011-01-01

... the objectives set forth at 47 U.S.C. 393(b), the Agency has developed the following categories. Each... nonbroadcast projects offering educational or instructional services). (b) Broadcast applications. The... telecommunications signal is distant when the geographical area to which the source is brought is beyond the grade B...

15 CFR 2301.4 - Types of projects and broadcast priorities.

Code of Federal Regulations, 2012 CFR

2012-01-01

... the objectives set forth at 47 U.S.C. 393(b), the Agency has developed the following categories. Each... nonbroadcast projects offering educational or instructional services). (b) Broadcast applications. The... telecommunications signal is distant when the geographical area to which the source is brought is beyond the grade B...

15 CFR 2301.4 - Types of projects and broadcast priorities.

Code of Federal Regulations, 2013 CFR

2013-01-01

... the objectives set forth at 47 U.S.C. 393(b), the Agency has developed the following categories. Each... nonbroadcast projects offering educational or instructional services). (b) Broadcast applications. The... telecommunications signal is distant when the geographical area to which the source is brought is beyond the grade B...

Cosmic String Searches

NASA Astrophysics Data System (ADS)

Hoffman, Y.; Hogan, C.

The author discusses observational strategies for finding effects associated with the gravitational lensing of distant objects by strings. In particular, the requirements of a survey to find chains of galaxy image pairs or single galaxies with sharp edges are studied in some detail, and a proposed search program at Steward Observatory is described.

OSSOS. IV. Discovery of a Dwarf Planet Candidate in the 9:2 Resonance with Neptune

NASA Technical Reports Server (NTRS)

Bannister, Michele T.; Alexandersen, Mike; Benecchi, Susan; Chen, Ying-Tung; Delsanti, Audrey; Fraser, Wesley C.; Gladman, Brett; Granvik, Mikael; Grundy, Will M.; Guilbert-Lepoutre, Aurelie;

Spacetime Dynamics and Slow Neutrino Background

NASA Astrophysics Data System (ADS)

Zhang, Tianxi

2018-06-01

Space is a form of existence of matter, while time is a measure of change of the matter in the space. Issac Newton suggested that the space and time are absolute, not affected by matter and its motion. His first law of motion or the law of inertia says that, without net force acts on it, an object in motion remains the motion in a straight line at a constant speed. Ernest Mach proposed that the inertia of a body results from the gravitational interaction on the body by the rest of the entire universe. As mass is a measure of inertia, Mach’s principle can be simply stated as mass here is affected by matter there. On the basis of Mach’s principle, Albert Einstein considered the space and time to be relative and developed two theories of relativities. One called special relativity describes the effect of motion on spacetime and the other called general relativity describes the effect of matter on spacetime. Recently, the author has further considered reactions of the influenced spacetime on the moving objects, including photons. A moving object including a photon, because of its continuously keeping on displacement, disturbs the rest of the entire universe or distorts/curves the spacetime. The distorted or curved spacetime then generates an effective gravitational force to act back on the moving object or photon, so that reduces the object inertia or photon frequency. Considering the disturbance of spacetime by a photon is extremely weak, the author has modelled the effective gravitational force to be Newtonian and derived a new redshift-distance relation that not only perfectly explained the redshift-distance measurement of distant type Ia supernovae but also inherently obtained Hubble’s law as an approximate at small redshift. In this study, we will further analyse the reaction of the influenced spacetime on moving neutrinos and demonstrate the creation of slow neutrino (or tired neutrino) background that may be gravitationally orbiting around clusters, galaxies, and any celestial objects to play a role of dark mater in explaining the excess of galactic and clustery rotations. This work was supported by NSF/REU (Grant #: PHY-1559870) at Alabama A & M University.

SU-F-R-10: Selecting the Optimal Solution for Multi-Objective Radiomics Model

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhou, Z; Folkert, M; Wang, J

2016-06-15

Purpose: To develop an evidential reasoning approach for selecting the optimal solution from a Pareto solution set obtained by a multi-objective radiomics model for predicting distant failure in lung SBRT. Methods: In the multi-objective radiomics model, both sensitivity and specificity are considered as the objective functions simultaneously. A Pareto solution set with many feasible solutions will be resulted from the multi-objective optimization. In this work, an optimal solution Selection methodology for Multi-Objective radiomics Learning model using the Evidential Reasoning approach (SMOLER) was proposed to select the optimal solution from the Pareto solution set. The proposed SMOLER method used the evidentialmore » reasoning approach to calculate the utility of each solution based on pre-set optimal solution selection rules. The solution with the highest utility was chosen as the optimal solution. In SMOLER, an optimal learning model coupled with clonal selection algorithm was used to optimize model parameters. In this study, PET, CT image features and clinical parameters were utilized for predicting distant failure in lung SBRT. Results: Total 126 solution sets were generated by adjusting predictive model parameters. Each Pareto set contains 100 feasible solutions. The solution selected by SMOLER within each Pareto set was compared to the manually selected optimal solution. Five-cross-validation was used to evaluate the optimal solution selection accuracy of SMOLER. The selection accuracies for five folds were 80.00%, 69.23%, 84.00%, 84.00%, 80.00%, respectively. Conclusion: An optimal solution selection methodology for multi-objective radiomics learning model using the evidential reasoning approach (SMOLER) was proposed. Experimental results show that the optimal solution can be found in approximately 80% cases.« less

History of Chandra X-Ray Observatory

NASA Image and Video Library

2000-10-01

This most distant x-ray cluster of galaxies yet has been found by astronomers using Chandra X-ray Observatory (CXO). Approximately 10 billion light-years from Earth, the cluster 3C294 is 40 percent farther than the next most distant x-ray galaxy cluster. The existence of such a faraway cluster is important for understanding how the universe evolved. CXO's image reveals an hourglass-shaped region of x-ray emissions centered on the previously known central radio source (seen in this image as the blue central object) that extends outward for 60,000 light- years. The vast clouds of hot gas that surround such galaxies in clusters are thought to be heated by collapse toward the center of the cluster. Until CXO, x-ray telescopes have not had the needed sensitivity to identify such distant clusters of galaxies. Galaxy clusters are the largest gravitationally bound structures in the universe. The intensity of the x-rays in this CXO image of 3C294 is shown as red for low energy x-rays, green for intermediate, and blue for the most energetic x-rays. (Photo credit: NASA/loA/A. Fabian et al)

The “Minimizing Antibiotic Resistance in Colorado” Project: Impact of Patient Education in Improving Antibiotic Use in Private Office Practices

PubMed Central

Gonzales, Ralph; Corbett, Kitty K; Leeman-Castillo, Bonnie A; Glazner, Judith; Erbacher, Kathleen; Darr, Carol A; Wong, Shale; Maselli, Judith H; Sauaia, Angela; Kafadar, Karen

2005-01-01

Objective To assess the marginal impact of patient education on antibiotic prescribing to children with pharyngitis and adults with acute bronchitis in private office practices. Data Sources/Study Setting Antibiotic prescription rates based on claims data from four managed care organizations in Colorado during baseline (winter 2000) and study (winter 2001) periods. Study Design A nonrandomized controlled trial of a household and office-based patient educational intervention was performed. During both periods, Colorado physicians were mailed antibiotic prescribing profiles and practices guidelines as part of an ongoing quality improvement program. Intervention practices (n=7) were compared with local and distant control practices. Data Collection/Extraction Methods Office visits were extracted by managed care organizations using International Classification of Diseases-9-Clinical Modification codes for acute respiratory tract infections, and merged with pharmacy claims data based on visit and dispensing dates coinciding within 2 days. Principal Findings Adjusted antibiotic prescription rates during baseline and study periods increased from 38 to 39 percent for pediatric pharyngitis at the distant control practices, and decreased from 39 to 37 percent at the local control practices, and from 34 to 30 percent at the intervention practices (p=.18 compared with distant control practices). Adjusted antibiotic prescription rates decreased from 50 to 44 percent for adult bronchitis at the distant control practices, from 55 to 45 percent at the local control practices, and from 60 to 36 percent at the intervention practices (p<.002 and p=.006 compared with distant and local control practices, respectively). Conclusions In office practices, there appears to be little room for improvement in antibiotic prescription rates for children with pharyngitis. In contrast, patient education helps reduce antibiotic use for adults with acute bronchitis beyond that achieved by physician-directed efforts. PMID:15663704

The Number of Pathologically Positive Lymph Nodes and Pathological Tumor Depth Predicts Prognosis in Patients With Poorly Differentiated Squamous Cell Carcinoma of the Oral Cavity

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kang, Chung-Jan; Head and Neck Oncology Group, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan; Lin, Chien-Yu

2011-11-15

Purpose: The objective of this retrospective study was twofold: (1) to investigate prognostic factors for clinical outcomes in patients with poorly differentiated oral cavity squamous cell carcinoma and (2) to identify specific prognostic subgroups that may help to guide treatment decisions. Methods and Materials: We examined 102 patients with poorly differentiated oral cavity squamous cell carcinoma. All patients were followed for at least 24 months after surgery or until death. The 5-year rates of local control, neck control, distant metastasis, disease-free, disease-specific, and overall survival served as main outcome measures. Results: The 5-year rates were as follows: local control (79%),more » neck control (64%), distant metastases (27%), disease-free survival (48%), disease-specific survival (52%), and overall survival (42%). Multivariable analysis showed that the number of pathologically positive nodes ({>=}4 vs. {<=}3) was a significant predictor of neck control, distant metastasis, and disease-free, disease-specific, and overall survival rates. In addition, the presence of tumor depth of {>=}11 mm (vs. <11 mm) was a significant predictor of distant metastasis, disease-specific survival, and overall survival rates. The combination of the two predictors (26.5%, 27/102) was independently associated with poorer neck control (p = 0.0319), distant metastasis (p < 0.0001), and disease-free (p < 0.0001), disease-specific (p < 0.0001), and overall survival (p < 0.0001) rates. Conclusions: In patients with poorly differentiated oral cavity squamous cell carcinoma, the presence of at least 4 pathologically positive lymph nodes and of a pathological tumor depth {>=}11 mm identifies a subset of subjects with poor clinical outcomes. Patients carrying both risk factors are suitable candidates for the development of novel therapeutic approaches.« less

Review of the leafhopper genus Penthimia Germar (Hemiptera: Cicadellidae: Deltocephalinae) from the Indian subcontinent with description of seven new species.

PubMed

Shobharani, M; Viraktamath, C A; Webb, M D

2018-01-02

Species of the leafhopper genus Penthimia Germar known from the Indian subcontinent are reviewed based on the examination of type specimens. Seven new species of the genus, Penthimia curvata sp. nov. (Karnataka: Bandipur), P. meghalayensis sp. nov. (Meghalaya: Nangpoh), P. neoattenuata sp. nov. (India: Tamil Nadu), P. ribhoi sp. nov. (India: Meghalaya), P. sahyadrica sp. nov. (Karnataka: Dharmasthala, Agumbe; Kerala: Thekkady), P. spiculata sp. nov. (Karnataka: Nagarahole) and P. tumida sp. nov. (Tamil Nadu: Ootacamund; Kerala: Munnar) are described. The following nomenclatorial changes are proposed: Penthimia alba Zahniser, McKamey Dmitriev, 2012 (replacement name for P. thoracica Distant, 1918, nec Panzer, 1799), syn. nov. of P. quadrinotata Distant, 1918; Neodartus scutellatus Distant, 1908 syn. nov. of Penthimia ereba Distant 1908; P. nilgiriensis Distant, 1918 syn. nov. of P. montana Distant, 1918; P. scutellata (Distant) comb. nov. (from genus Neodartus); a lectotype is designated for P. maculosa Distant, stat. revived, thereby removing its synonymy with P. scapularis Distant. The following other lectotypes are designated: P. attenuata Distant, P. subniger Distant, P. scapularis Distant, P. distanti Baker, P. ereba Distant, N. scutellatus Distant, P. fraterna Distant, P. funebris Distant, P. juno Distant, P. maculosa Distant, P. montana Distant, P. noctua Distant, P. quadrinotata Distant, P. alba Zahniser, McKamey Dmitriev. Examination of types of Penthimia rufopunctata Motschulsky revealed that it belongs to Penthimia and hence it is transferred back to that genus from Neodartus, revised placement. The following species previously included in the genus Penthimia are transferred to the genera Tambila Distant and Vulturnus Kirkaldy: Tambila badia (Distant) comb. nov., T. majuscula (Distant) comb. nov., T. vittatifrons (Distant) comb. nov., T. variabilis (Distant) comb. nov. and Vulturnus flavocapitata (Distant) comb. nov. Three species are treated in a new Penthimia compacta Walker complex, i.e., Penthimia compacta Walker 1851, Penthimia subniger Distant 1908 and Penthimia scapularis Distant 1908. All taxa are described and a key to Penthimiini genera found in the subcontinent and also a key to species of Penthimia are included.

Minimizing metastatic risk in radiotherapy fractionation schedules

NASA Astrophysics Data System (ADS)

Badri, Hamidreza; Ramakrishnan, Jagdish; Leder, Kevin

2015-11-01

Metastasis is the process by which cells from a primary tumor disperse and form new tumors at distant anatomical locations. The treatment and prevention of metastatic cancer remains an extremely challenging problem. This work introduces a novel biologically motivated objective function to the radiation optimization community that takes into account metastatic risk instead of the status of the primary tumor. In this work, we consider the problem of developing fractionated irradiation schedules that minimize production of metastatic cancer cells while keeping normal tissue damage below an acceptable level. A dynamic programming framework is utilized to determine the optimal fractionation scheme. We evaluated our approach on a breast cancer case using the heart and the lung as organs-at-risk (OAR). For small tumor α /β values, hypo-fractionated schedules were optimal, which is consistent with standard models. However, for relatively larger α /β values, we found the type of schedule depended on various parameters such as the time when metastatic risk was evaluated, the α /β values of the OARs, and the normal tissue sparing factors. Interestingly, in contrast to standard models, hypo-fractionated and semi-hypo-fractionated schedules (large initial doses with doses tapering off with time) were suggested even with large tumor α/β values. Numerical results indicate the potential for significant reduction in metastatic risk.

Galaxy Evolution Across The Redshift Desert

NASA Astrophysics Data System (ADS)

Kotulla, Ralf

2010-01-01

GALEV evolutionary synthesis models are an ideal tool to study the formation and evolution of galaxies. I present a large model grid that contains undisturbed E and Sa-Sd type galaxies as well as a wide range of models undergoing starbursts of various strengths and at different times and also includes the subsequent post-starburst phases for these galaxies. This model grid not only allows to describe and refine currently used color selection criteria for Lyman Break Galaxies, BzK galaxies, Extremely Red Objects (ERO) and both Distant and Luminous Red Galaxies (DRG, LRG). It also gives accurate stellar masses, gas fractions, star formation rates, metallicities and burst strengths for an unprecedentedly large sample of galaxies with multi-band photometry. We find, amongst other things, that LBGs are most likely progenitors of local early type spiral galaxies and low-mass ellipticals. We are for the first time able to reproduce E+A features in EROs by post-starbursts as an alternative to dusty starforming galaxies and predict how to discriminate between these scenarios. Our results from photometric analyses perfectly agree with all available spectroscopic information and open up a much wider perspective, including the bulk of the less luminous and more typical galaxy population, in the redshift desert and beyond. All model data are available online at http://www.galev.org.

MAD ADAPTIVE OPTICS IMAGING OF HIGH-LUMINOSITY QUASARS: A PILOT PROJECT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liuzzo, E.; Falomo, R.; Paiano, S.

2016-08-01

We present near-IR images of five luminous quasars at z ∼ 2 and one at z ∼ 4 obtained with an experimental adaptive optics (AO) instrument at the European Southern Observatory Very Large Telescope. The observations are part of a program aimed at demonstrating the capabilities of multi-conjugated adaptive optics imaging combined with the use of natural guide stars for high spatial resolution studies on large telescopes. The observations were mostly obtained under poor seeing conditions but in two cases. In spite of these nonoptimal conditions, the resulting images of point sources have cores of FWHM ∼ 0.2 arcsec. Wemore » are able to characterize the host galaxy properties for two sources and set stringent upper limits to the galaxy luminosity for the others. We also report on the expected capabilities for investigating the host galaxies of distant quasars with AO systems coupled with future Extremely Large Telescopes. Detailed simulations show that it will be possible to characterize compact (2–3 kpc) quasar host galaxies for quasi-stellar objects at z = 2 with nucleus K -magnitude spanning from 15 to 20 (corresponding to absolute magnitude −31 to −26) and host galaxies that are 4 mag fainter than their nuclei.« less

Heat and hydration status: Predictors of repeated measures of urine specific gravity among Tsimane' adults in the Bolivian Amazon.

PubMed

Rosinger, Asher

2015-12-01

Hydration status is critical to physiological and cognitive health, yet it is unclear how populations living in hot-humid environments experiencing lifestyle transitions manage this underexplored facet of heat adaptation. This study assesses the predictors of repeated measures of hydration status for adults from two villages (close and distant from a market town) in the Bolivian Amazon. Interviews and focal follows were conducted with 36 Tsimane' (50% male). Urine samples, temperature, activity levels, and anthropometrics were measured pre-interview and post-follow and yielded a small panel (72 observations). Urine samples were analyzed for urine specific gravity (USG), a biomarker of hydration, with a refractometer. The mean USG was 1.020 g/ml (SD ± 0.008) with men (1.022 ± 0.008) slightly more dehydrated than women (1.018 ± 0.007). Using 1.020 as the criteria for clinical dehydration, 42% of the participants were dehydrated at both intervals and 21% were extremely dehydrated. Controlling for activity level, village membership, and covariates in random-effects linear regression models, each degree centigrade increase was associated with a USG increase of 0.0008 g/ml (P = 0.000). Adults from the village closer to the market town had significantly higher USG (B = 0.0041; P = 0.04) than those in the distant village. Dehydration was predicted to occur at 29°C, just above the thermoneutral range, and extreme dehydration at 37°C. These findings suggest that hotter temperatures coupled with lifestyle transitions may create conditions that increase vulnerability to dehydration among rural populations through landscape modifications and diet changes. © 2015 Wiley Periodicals, Inc.

Long-term results of a phase 2 study of neoadjuvant chemotherapy and radiotherapy in the management of high-risk, high-grade, soft tissue sarcomas of the extremities and body wall: Radiation Therapy Oncology Group Trial 9514.

PubMed

Kraybill, William G; Harris, Jonathan; Spiro, Ira J; Ettinger, David S; DeLaney, Thomas F; Blum, Ronald H; Lucas, David R; Harmon, David C; Letson, G Douglas; Eisenberg, Burton

2010-10-01

The use of neoadjuvant and adjuvant chemotherapy in soft tissue sarcomas is controversial. This is a report of long-term (≥5 years) follow-up in patients with high-grade, high-risk soft tissue sarcomas treated with neoadjuvant chemotherapy, preoperative radiotherapy (RT), and adjuvant chemotherapy. Patients with high-grade soft tissue sarcoma≥8 cm in diameter of the extremities and body wall received 3 cycles of neoadjuvant chemotherapy (mesna, doxorubicin, ifosfamide, and dacarbazine) and preoperative RT (44 grays administered in split courses), and 3 cycles of postoperative chemotherapy (mesna, doxorubicin, ifosfamide, and dacarbazine). Sixty-four of 66 patients were analyzed. After chemotherapy and RT, 61 patients had surgery; 58 had R0 resections (5 amputations), and 3 had R1 resections. Ninety-seven percent experienced grade 3 or higher toxicity, including 3 deaths. These toxicities were short term. With a median follow-up of 7.7 years in surviving patients, the 5-year rates of locoregional failure (including amputation), and distant metastasis were 22.2% (95% confidence interval [CI], 11.8-32.6) and 28.1% (95% CI, 17.0-39.2). The most common site of metastasis was lung. Estimated 5-year rates of disease-free survival, distant disease-free survival, and overall survival were 56.1% (95% CI, 43.9-68.3), 64.1% (95% CI, 52.3-75.8), and 71.2% (95% CI, 60.0-82.5), respectively. Although the toxicity was significant, it was limited in its course and for the most part resolved by 1 year. The long-term outcome was better than might be expected in such high-risk tumors. Copyright © 2010 American Cancer Society.

Multi-arm spectrometer for parallel frequency analysis of radio-wave signals oriented to astronomical observations

NASA Astrophysics Data System (ADS)

Shcherbakov, Alexandre S.; Chavez Dagostino, Miguel; Arellanes, Adan Omar; Tepichin Rodriguez, Eduardo

2017-08-01

We describe a potential prototype of modern spectrometer based on acousto-optical technique with three parallel optical arms for analysis of radio-wave signals specific to astronomical observations. Each optical arm exhibits original performances to provide parallel multi-band observations with different scales simultaneously. Similar multi-band instrument is able to realize measurements within various scenarios from planetary atmospheres to attractive objects in the distant Universe. The arrangement under development has two novelties. First, each optical arm represents an individual spectrum analyzer with its individual performances. Such an approach is conditioned by exploiting various materials for acousto-optical cells operating within various regimes, frequency ranges, and light wavelengths from independent light sources. Individually produced beam shapers give both the needed incident light polarization and the required apodization for light beam to increase the dynamic range of the system as a whole. After parallel acousto-optical processing, a few data flows from these optical arms are united by the joint CCD matrix on the stage of the combined extremely high-bit rate electronic data processing that provides the system performances as well. The other novelty consists in the usage of various materials for designing wide-aperture acousto-optical cells exhibiting the best performances within each of optical arms. Here, one can mention specifically selected cuts of tellurium dioxide, bastron, and lithium niobate, which overlap selected areas within the frequency range from 40 MHz to 2.0 GHz. Thus one yields the united versatile instrument for comprehensive studies of astronomical objects simultaneously with precise synchronization in various frequency ranges.

Direct imaging search for the "missing link" in giant planet formation

NASA Astrophysics Data System (ADS)

Ngo, Henry; Mawet, Dimitri; Ruane, Garreth; Xuan, Wenhao; Bowler, Brendan; Cook, Therese; Zawol, Zoe

2018-01-01

While transit and radial velocity detection techniques have probed giant planet populations at close separations (within a few au), current direct imaging surveys are finding giant planets at separations of 10s-100s au. Furthermore, these directly imaged planets are very massive, including some with masses above the deuterium burning limit. It is not certain whether these objects represent the high mass end of planet formation scenarios or the low mass end of star formation. We present a direct imaging survey to search for the "missing link" population between the close-in RV and transiting giant planets and the extremely distant directly imaged giant planets (i.e. giant planets between 5-10 au). Finding and characterizing this population allows for comparisons with the formation models of closer-in planets and connects directly imaged planets with closer-in planets in semi-major axis phase space. In addition, microlensing surveys have suggested a large reservoir of giant planets exist in this region. To find these "missing link" giant planets, our survey searches for giant planets around M-stars. The ubiquity of M-stars provide a large number of nearby targets and their L-band contrast with planets allow for sensitivities to smaller planet masses than surveys conducted at shorter wavelengths. Along with careful target selection, we use Keck's L-band vector vortex coronagraph to enable sensitivities of a few Jupiter masses as close as 4 au to their host stars. We present our completed 2-year survey targeting 200 young (10-150 Myr), nearby M-stars and our ongoing work to follow-up over 40 candidate objects.

A Practical Ontology Query Expansion Algorithm for Semantic-Aware Learning Objects Retrieval

ERIC Educational Resources Information Center

Lee, Ming-Che; Tsai, Kun Hua; Wang, Tzone I.

2008-01-01

Following the rapid development of Internet, particularly web page interaction technology, distant e-learning has become increasingly realistic and popular. To solve the problems associated with sharing and reusing teaching materials in different e-learning systems, several standard formats, including SCORM, IMS, LOM, and AICC, etc., recently have…

Radar: Human Safety Net

ERIC Educational Resources Information Center

Ritz, John M.

2016-01-01

Radar is a technology that can be used to detect distant objects not visible to the human eye. A predecessor of radar, called the telemobiloscope, was first used to detect ships in the fog in 1904 off the German coast. Many scientists have worked on the development and refinement of radar (Hertz with electromagnetic waves; Popov with determining…

Off-Site Distance Education Faculty: A Checklist of Considerations

ERIC Educational Resources Information Center

Stewart, Barbara L.; Goodson, Carole; Miertschin, Susan

2012-01-01

Case studies informed the development of a checklist for use in determining whether to engage in online educational practices whereby the family and consumer sciences (FCS) instructor teaches from a location distant from campus.Objective and subjective case details were recorded and analyzed for commonality and variance. From cross-case analysis,…

Knowledge Transfer between Two Geographically Distant Action Research Teams

ERIC Educational Resources Information Center

Desmarais, Lise; Parent, Robert; Leclerc, Louise; Raymond, Lysanne; MacKinnon, Scott; Vezina, Nicole

2009-01-01

Purpose: The objective of this study is to observe and document the transfer of a train the trainers program in knife sharpening and steeling. This knowledge transfer involved two groups of researchers: the experts and the learners. These groups are from geographically dispersed regions and evolve in distinct contexts by their language and…

Economics and Education for Human Flourishing: Wendell Berry and the "Oikonomic" Alternative to Neoliberalism

ERIC Educational Resources Information Center

Henderson, Joseph A.; Hursh, David W.

2014-01-01

Neoliberal ideologies and policies have transformed how we think about the economy, education, and the environment. Economics is presented as objective and quantifiable, best left to distant experts who develop algorithms regarding different monetary relations in our stead. This same kind of thinking--technical, numerical, decontextualized, and…

Discovering Our Stellar Neighborhood

ERIC Educational Resources Information Center

Black, David V.

2014-01-01

The stars closest to Earth are not particularly remarkable or exciting. They are average stars typical of the spiral arms of our Milky Way galaxy. In fact, until recently, most astronomy and Earth science textbooks ignored all but the largest of them to focus on distant, more exotic objects like red supergiants or black holes. The recent discovery…

The La Silla-QUEST Kuiper Belt Survey

NASA Astrophysics Data System (ADS)

Rabinowitz, David; Schwamb, Megan E.; Hadjiyska, Elena; Tourtellotte, Suzanne

2012-11-01

We describe the instrumentation and detection software and characterize the detection efficiency of an automated, all-sky, southern-hemisphere search for Kuiper Belt Objects (KBOs) brighter than R mag 21.4. The search relies on Yale University's 160 Megapixel QUEST camera, previously used for the successful surveys at Palomar that detected most of the distant dwarf planets, and now installed on the ESO 1.0 m Schmidt telescope at La Silla, Chile. Extensive upgrades were made to the telescope control system to support automation, and significant improvements were made to the camera. To date, 63 new KBOs have been discovered, including a new member of the Haumea collision family (2009 YE7) and a new distant object with an inclination exceeding 70° (2010 WG9). In a survey covering ~7500 deg2, we have thus far detected 77 KBOs and Centaurs, more than any other full-hemisphere search to date. Using a pattern of dithered pointings, we demonstrate a search efficiency exceeding 80%. We are currently on track to complete the southern-sky survey and detect any bright KBOs that have eluded detection from the north.

GRAVITATIONAL LENS CAPTURES IMAGE OF PRIMEVAL GALAXY

NASA Technical Reports Server (NTRS)

2002-01-01

This Hubble Space Telescope image shows several blue, loop-shaped objects that actually are multiple images of the same galaxy. They have been duplicated by the gravitational lens of the cluster of yellow, elliptical and spiral galaxies - called 0024+1654 - near the photograph's center. The gravitational lens is produced by the cluster's tremendous gravitational field that bends light to magnify, brighten and distort the image of a more distant object. How distorted the image becomes and how many copies are made depends on the alignment between the foreground cluster and the more distant galaxy, which is behind the cluster. In this photograph, light from the distant galaxy bends as it passes through the cluster, dividing the galaxy into five separate images. One image is near the center of the photograph; the others are at 6, 7, 8, and 2 o'clock. The light also has distorted the galaxy's image from a normal spiral shape into a more arc-shaped object. Astronomers are certain the blue-shaped objects are copies of the same galaxy because the shapes are similar. The cluster is 5 billion light-years away in the constellation Pisces, and the blue-shaped galaxy is about 2 times farther away. Though the gravitational light-bending process is not new, Hubble's high resolution image reveals structures within the blue-shaped galaxy that astronomers have never seen before. Some of the structures are as small as 300 light-years across. The bits of white imbedded in the blue galaxy represent young stars; the dark core inside the ring is dust, the material used to make stars. This information, together with the blue color and unusual 'lumpy' appearance, suggests a young, star-making galaxy. The picture was taken October 14, 1994 with the Wide Field Planetary Camera-2. Separate exposures in blue and red wavelengths were taken to construct this color picture. CREDIT: W.N. Colley and E. Turner (Princeton University), J.A. Tyson (Bell Labs, Lucent Technologies) and NASA Image files in GIF and JPEG format and captions may be accessed on Internet via anonymous ftp from oposite.stsci.edu in /pubinfo.

CD117 expression in operable oesophageal squamous cell carcinomas predicts worse clinical outcome

PubMed Central

Fan, Huijie; Yuan, Yuan; Wang, Junsheng; Zhou, Fuyou; Zhang, Mingzhi; Giercksky, Karl-Erik; Nesland, Jahn M; Suo, Zhenhe

2013-01-01

Aims To investigate the aberrant expression of CD117 in oesophageal squamous cell carcinoma (SCC) and its prognostic significance. Methods and results Immunohistochemical staining for CD117 was performed on tissue microarray and routine tissue sections from 157 oesophageal SCC patients and 10 normal oesophageal epithelia adjacent to tumour. The positive rate of CD117 expression was 29.9% in oesophageal SCC tissues, whereas no CD117 expression was detected in the 10 normal oesophageal epithelia. CD117 expression was significantly associated with T stage (P < 0.001), distant metastasis (P = 0.015), lymph node metastasis (P = 0.019), and clinical stage (P = 0.021). Progression-free survival in the patients with CD117-positive tumours was shorter than that in the patients with CD117-negative tumours (P = 0.010). In univariate analyses, CD117 expression was the most significant factor for overall survival of oesophageal SCC patients (P < 0.001), followed by lymph node metastasis (P = 0.001), T stage (P = 0.002), clinical stage (P = 0.006), distant metastasis (P = 0.020), and histological grade (P = 0.027). Multivariate analyses verified that CD117 expression was an independent prognostic marker for oesophageal SCC patients (P = 0.002). In addition, CD117 expression predicted poorer survival in patients without distant metastases. Conclusions CD117 expression in operable oesophageal SCC may be a valuable prognostic marker, and detection of its expression in clinical samples may be useful in defining a subclass of oesophageal SCCs with extremely poor clinical outcome, which may require a specially targeted treatment modality. PMID:23570416

Augmentation of blood circulation to the fingers by warming distant body areas

NASA Technical Reports Server (NTRS)

Koscheyev, V. S.; Leon, G. R.; Paul, S.; Tranchida, D.; Linder, I. V.

2000-01-01

Future activities in space will require greater periods of time in extreme environments in which the body periphery will be vulnerable to chilling. Maintaining the hands and fingers in comfortable conditions enhances finger flexibility and dexterity, and thus effects better work performance. We have evaluated the efficacy of promoting heat transfer and release by the extremities by increasing the blood flow to the periphery from more distant parts of the body. The experimental garment paradigm developed by the investigators was used to manipulate the temperature of different body areas. Six subjects, two females and four males, were evaluated in a stage-1 baseline condition, with the inlet temperature of the circulating water in the liquid cooling/warming garment (LCWG) at 33 degrees C. At stage 2 the total LCWG water inlet temperature was cooled to 8 degrees C, and at stage 3 the inlet water temperature in specific segments of the LCWG was warmed (according to protocol) to 45 degrees C, while the inlet temperature in the rest of the LCWG was maintained at 8 degrees C. The following four body-area-warming conditions were studied in separate sessions: (1) head, (2) upper torso/arm, (3) upper torso/arm/head, and (4) legs/feet. Skin temperature, heat flux and blood perfusion of the fingers, and subjective perception of thermal sensations and overall physical comfort were assessed. Finger temperature (T(fing)) analyses showed a statistically significant condition x stage interaction. Post-hoc comparisons (T(fing)) indicated that at stage 3, the upper torso/arm/head warming condition was significantly different from the head, upper torso/arm and legs/feet conditions, showing an increase in T(fing). There was a significant increase in blood perfusion in the fingers at stage 3 in all conditions. Subjective perception of hand warmth, and overall physical comfort level significantly increased in the stage 3 upper torso/arm/head condition. The findings indicate that physiological methods to enhance heat transfer by the blood to the periphery within protective clothing provide an additional tool for increasing total and local human comfort in extreme environments.

A Precision, Low-Cost GPS-Based Transmitter Synchronization Scheme for Improved AM Reception

DOE Office of Scientific and Technical Information (OSTI.GOV)

Smith, Stephen Fulton; Moore, Anthony

2009-01-01

This paper describes a highly accurate carrier-frequency synchronization scheme for actively, automatically locking multiple, remotely located AM broadcast transmitters to a common frequency/timing reference source such as GPS. The extremely tight frequency lock (to {approx}1 part in 10{sup 9} or better) permits the effective elimination of audible and even sub-audible beats between the local (desired) station's carrier signal and the distant stations carriers, usually received via skywave propagation during the evening and nighttime hours. These carrier-beat components cause annoying modulations of the desired station's audio at the receiver and concurrent distortion of the audio modulation from the distant station(s) andmore » often cause listeners to ldquotune outrdquo due to the low reception quality. Significant reduction or elimination of the beats and related effects will greatly enlarge the effective (interference-limited) listening area of the desired station (from 4 to 10 times as indicated in our tests) and simultaneously reduce the corresponding interference of the local transmitter to the distant stations as well. In addition, AM stereo (CQUAM) reception will be particularly improved by minimizing the phase shifts induced by co-channel interfering signals; hybrid digital (HD) signals will also benefit via reduction in beats from analog signals. The automatic frequency-control hardware described is inexpensive ($1000-$2000), requires no periodic recalibration, has essentially zero long-term drift, and could employ alternate wide-area frequency references of suitable accuracy, including broadcasts from WWVB, LORAN-C, and equivalent sources. The basic configuration of the GPS-disciplined oscillator which solves this problem is extremely simple. The main oscillator is a conventional high-stability quartz-crystal type. To counter long- term drifts, the oscillator is slightly adjusted to track a high-precision source of standard frequency obtained from a specialized GPS receiver (or other source), usually at 10.000 MHz. This very stable local reference frequency is then used as a clock for a standard digitally implemented frequency synthesizer, which is programmed to generate the specific carrier frequency desired. The stability of the disciplining source, typically {approx}1 part in 10{sup 9} to 10{sup 11}, is thus transferred to the final AM transmitter carrier output frequency.« less

OSSOS. V. Diffusion in the Orbit of a High-perihelion Distant Solar System Object

NASA Astrophysics Data System (ADS)

Bannister, Michele T.; Shankman, Cory; Volk, Kathryn; Chen, Ying-Tung; Kaib, Nathan; Gladman, Brett J.; Jakubik, Marian; Kavelaars, J. J.; Fraser, Wesley C.; Schwamb, Megan E.; Petit, Jean-Marc; Wang, Shiang-Yu; Gwyn, Stephen D. J.; Alexandersen, Mike; Pike, Rosemary E.

2017-06-01

We report the discovery of the minor planet 2013 SY99 on an exceptionally distant, highly eccentric orbit. With a perihelion of 50.0 au, 2013 SY99’s orbit has a semimajor axis of 730 ± 40 au, the largest known for a high-perihelion trans-Neptunian object (TNO), and well beyond those of (90377) Sedna and 2012 VP113. Yet, with an aphelion of 1420 ± 90 au, 2013 SY99’s orbit is interior to the region influenced by Galactic tides. Such TNOs are not thought to be produced in the current known planetary architecture of the solar system, and they have informed the recent debate on the existence of a distant giant planet. Photometry from the Canada-France-Hawaii Telescope, Gemini North, and Subaru indicate 2013 SY99 is ˜250 km in diameter and moderately red in color, similar to other dynamically excited TNOs. Our dynamical simulations show that Neptune’s weak influence during 2013 SY99’s perihelia encounters drives diffusion in its semimajor axis of hundreds of astronomical units over 4 Gyr. The overall symmetry of random walks in the semimajor axis allows diffusion to populate 2013 SY99’s orbital parameter space from the 1000 to 2000 au inner fringe of the Oort cloud. Diffusion affects other known TNOs on orbits with perihelia of 45 to 49 au and semimajor axes beyond 250 au. This provides a formation mechanism that implies an extended population, gently cycling into and returning from the inner fringe of the Oort cloud.

Integrating ergonomics into engineering design: the role of objects.

PubMed

Hall-Andersen, Lene Bjerg; Broberg, Ole

2014-05-01

The objective of this study was to explore the role of objects in integrating ergonomic knowledge in engineering design processes. An engineering design case was analyzed using the theoretical concepts of boundary objects and intermediary objects: Boundary objects facilitate collaboration between different knowledge domains, while the aim of an intermediary object is to circulate knowledge and thus produce a distant effect. Adjustable layout drawings served as boundary objects and had a positive impact on the dialog between an ergonomist and designers. An ergonomic guideline document was identified as an intermediary object. However, when the ergonomic guidelines were circulated in the design process, only some of the guidelines were transferred to the design of the sterile processing plant. Based on these findings, recommendations for working with objects in design processes are included. Copyright © 2013 Elsevier Ltd and The Ergonomics Society. All rights reserved.

DeepAnomaly: Combining Background Subtraction and Deep Learning for Detecting Obstacles and Anomalies in an Agricultural Field.

PubMed

Christiansen, Peter; Nielsen, Lars N; Steen, Kim A; Jørgensen, Rasmus N; Karstoft, Henrik

2016-11-11

Convolutional neural network (CNN)-based systems are increasingly used in autonomous vehicles for detecting obstacles. CNN-based object detection and per-pixel classification (semantic segmentation) algorithms are trained for detecting and classifying a predefined set of object types. These algorithms have difficulties in detecting distant and heavily occluded objects and are, by definition, not capable of detecting unknown object types or unusual scenarios. The visual characteristics of an agriculture field is homogeneous, and obstacles, like people, animals and other obstacles, occur rarely and are of distinct appearance compared to the field. This paper introduces DeepAnomaly, an algorithm combining deep learning and anomaly detection to exploit the homogenous characteristics of a field to perform anomaly detection. We demonstrate DeepAnomaly as a fast state-of-the-art detector for obstacles that are distant, heavily occluded and unknown. DeepAnomaly is compared to state-of-the-art obstacle detectors including "Faster R-CNN: Towards Real-Time Object Detection with Region Proposal Networks" (RCNN). In a human detector test case, we demonstrate that DeepAnomaly detects humans at longer ranges (45-90 m) than RCNN. RCNN has a similar performance at a short range (0-30 m). However, DeepAnomaly has much fewer model parameters and (182 ms/25 ms =) a 7.28-times faster processing time per image. Unlike most CNN-based methods, the high accuracy, the low computation time and the low memory footprint make it suitable for a real-time system running on a embedded GPU (Graphics Processing Unit).

DeepAnomaly: Combining Background Subtraction and Deep Learning for Detecting Obstacles and Anomalies in an Agricultural Field

PubMed Central

Christiansen, Peter; Nielsen, Lars N.; Steen, Kim A.; Jørgensen, Rasmus N.; Karstoft, Henrik

2016-01-01

Convolutional neural network (CNN)-based systems are increasingly used in autonomous vehicles for detecting obstacles. CNN-based object detection and per-pixel classification (semantic segmentation) algorithms are trained for detecting and classifying a predefined set of object types. These algorithms have difficulties in detecting distant and heavily occluded objects and are, by definition, not capable of detecting unknown object types or unusual scenarios. The visual characteristics of an agriculture field is homogeneous, and obstacles, like people, animals and other obstacles, occur rarely and are of distinct appearance compared to the field. This paper introduces DeepAnomaly, an algorithm combining deep learning and anomaly detection to exploit the homogenous characteristics of a field to perform anomaly detection. We demonstrate DeepAnomaly as a fast state-of-the-art detector for obstacles that are distant, heavily occluded and unknown. DeepAnomaly is compared to state-of-the-art obstacle detectors including “Faster R-CNN: Towards Real-Time Object Detection with Region Proposal Networks” (RCNN). In a human detector test case, we demonstrate that DeepAnomaly detects humans at longer ranges (45–90 m) than RCNN. RCNN has a similar performance at a short range (0–30 m). However, DeepAnomaly has much fewer model parameters and (182 ms/25 ms =) a 7.28-times faster processing time per image. Unlike most CNN-based methods, the high accuracy, the low computation time and the low memory footprint make it suitable for a real-time system running on a embedded GPU (Graphics Processing Unit). PMID:27845717

HUBBLE AND KECK DISCOVER GALAXY BUILDING BLOCK

NASA Technical Reports Server (NTRS)

2002-01-01

This NASA Hubble Space Telescope image shows a very small, faint galaxy 'building block' newly discovered by a unique collaboration between ground- and space-based telescopes. Hubble and the 10-meter Keck Telescopes in Hawaii joined forces, using a galaxy cluster which acts as gravitational lens to detect what scientists believe is one of the smallest very distant objects ever found. The galaxy cluster Abell 2218 was used by a team of European and American astronomers led by Richard Ellis (Caltech) in their systematic search for intrinsically faint distant star-forming systems. Without help from Abell 2218's exceptional magnifying power to make objects appear about 30 times brighter, the galaxy building block would have been undetectable. In the image to the right, the object is seen distorted into two nearly identical, very red 'images' by the gravitational lens. The image pair represents the magnified result of a single background object gravitationally lensed by Abell 2218 and viewed at a distance of 13.4 billion light-years. The intriguing object contains only one million stars, far fewer than a mature galaxy, and scientists believe it is very young. Such young star-forming systems of low mass at early cosmic times are likely to be the objects from which present-day galaxies have formed. In the image to the left, the full overview of the galaxy cluster Abell 2218 is seen. This image was taken by Hubble in 1999 at the completion of Hubble Servicing Mission 3A. Credit: NASA, ESA, Richard Ellis (Caltech) and Jean-Paul Kneib (Observatoire Midi-Pyrenees, France) Acknowledgment: NASA, A. Fruchter and the ERO Team (STScI and ST-ECF)

Early Formed Astrophysical Objects and Cosmological Antimatter

NASA Astrophysics Data System (ADS)

Dolgov, Alexander D.

Astronomical observations of recent years show that the universe at high redshifts (about ten) is densely populated by early formed objects: bright galaxies, quasars, gamma-bursters, and it contains a lot of metals and dust. Such a rich variety of early formed objects have not been expected in the standard model of formation of astrophysical objects. There is serious tension between the standard theory and the observations. We describe the model which relaxes this tension and nicely fits the data. The model naturally leads to the creation of cosmologically significant antimatter which may be abundant even in the Galaxy. Phenomenological consequences of our scenario and the possibility of distant registration of antimatter are discussed.

Early formed astrophysical objects and cosmological antimatter

NASA Astrophysics Data System (ADS)

Dolgov, Alexander D.

2016-10-01

Astronomical observations of recent years show that the universe at high redshifts (about ten) is densely populated by early formed objects: bright galaxies, quasars, gamma-bursters, and it contains a lot of metals and dust. Such a rich variety of early formed objects have not been expected in the standard model of formation of astrophysical objects. There is serious tension between the standard theory and the observations. We describe the model which relaxes this tension and nicely fits the data. The model naturally leads to the creation of cosmologically significant antimatter which may be abundant even in the Galaxy. Phenomenological consequences of our scenario and the possibility of distant registration of antimatter are discussed.

The SCUBA HAlf Degree Extragalactic Survey (SHADES) - V. Submillimetre properties of near-infrared-selected galaxies in the Subaru/XMM -Newton deep field

NASA Astrophysics Data System (ADS)

Takagi, T.; Mortier, A. M. J.; Shimasaku, K.; Coppin, K.; Pope, A.; Ivison, R. J.; Hanami, H.; Serjeant, S.; Clements, D. L.; Priddey, R. S.; Dunlop, J. S.; Takata, T.; Aretxaga, I.; Chapman, S. C.; Eales, S. A.; Farrah, D.; Granato, G. L.; Halpern, M.; Hughes, D. H.; van Kampen, E.; Scott, D.; Sekiguchi, K.; Smail, I.; Vaccari, M.

2007-11-01

We have studied the submillimetre (submm) properties of the following classes of near-infrared-selected (NIR-selected) massive galaxies at high redshifts: BzK-selected star-forming galaxies (BzKs); distant red galaxies (DRGs); and extremely red objects (EROs). We used the SCUBA HAlf Degree Extragalactic Survey (SHADES), the largest uniform submm survey to date. Partial overlap of SIRIUS/NIR images and SHADES in Subaru/XMM-Newton deep field has allowed us to identify four submm-bright NIR-selected galaxies, which are detected in the mid-IR, 24μ m, and the radio, 1.4GHz. We find that all of our submm-bright NIR-selected galaxies satisfy the BzK selection criteria, i.e. BzK ≡ (z - K)AB - (B - z)AB >= -0.2, except for one galaxy whose B - z and z - K colours are however close to the BzK colour boundary. Two of the submm-bright NIR-selected galaxies satisfy all of the selection criteria we considered, i.e. they belong to the BzK-DRG-ERO overlapping population, or `extremely red' BzKs. Although these extremely red BzKs are rare (0.25 arcmin-2), up to 20 per cent of this population could be submm galaxies. This fraction is significantly higher than that found for other galaxy populations studied here. Via a stacking analysis, we have detected the 850-μ m flux of submm-faint BzKs and EROs in our SCUBA maps. While the contribution of z ~ 2 BzKs to the submm background is about 10-15 per cent and similar to that from EROs typically at z ~ 1, BzKs have a higher fraction (~30 per cent) of submm flux in resolved sources compared with EROs and submm sources as a whole. From the spectral energy distribution (SED) fitting analysis for both submm-bright and submm-faint BzKs, we found no clear signature that submm-bright BzKs are experiencing a specifically luminous evolutionary phase, compared with submm-faint BzKs. An alternative explanation might be that submm-bright BzKs are more massive than submm-faint ones.

Verifying a computational method for predicting extreme ground motion

USGS Publications Warehouse

Harris, R.A.; Barall, M.; Andrews, D.J.; Duan, B.; Ma, S.; Dunham, E.M.; Gabriel, A.-A.; Kaneko, Y.; Kase, Y.; Aagaard, Brad T.; Oglesby, D.D.; Ampuero, J.-P.; Hanks, T.C.; Abrahamson, N.

2011-01-01

In situations where seismological data is rare or nonexistent, computer simulations may be used to predict ground motions caused by future earthquakes. This is particularly practical in the case of extreme ground motions, where engineers of special buildings may need to design for an event that has not been historically observed but which may occur in the far-distant future. Once the simulations have been performed, however, they still need to be tested. The SCEC-USGS dynamic rupture code verification exercise provides a testing mechanism for simulations that involve spontaneous earthquake rupture. We have performed this examination for the specific computer code that was used to predict maximum possible ground motion near Yucca Mountain. Our SCEC-USGS group exercises have demonstrated that the specific computer code that was used for the Yucca Mountain simulations produces similar results to those produced by other computer codes when tackling the same science problem. We also found that the 3D ground motion simulations produced smaller ground motions than the 2D simulations.

Accretion and Outflow from a Magnetized, Neutrino Cooled Torus around the Gamma Ray Burst Central Engine

NASA Astrophysics Data System (ADS)

Janiuk, Agnieszka; Moscibrodzka, Monika

Gamma Ray Bursts (GRB) are the extremely energetic transient events, visible from the most distant parts of the Universe. They are most likely powered by accretion on the hyper-Eddington rates that proceeds onto a newly born stellar mass black hole. This central engine gives rise to the most powerful, high Lorentz factor jets that are responsible for energetic gamma ray emission. We investigate the accretion flow evolution in GRB central engine, using the 2D MHD simulations in General Relativity. We compute the structure and evolution of the extremely hot and dense torus accreting onto the fast spinning black hole, which launches the magnetized jets. We calculate the chemical structure of the disk and account for neutrino cooling. Our preliminary runs apply to the short GRB case (remnant torus accreted after NS-NS or NS-BH merger). We estimate the neutrino luminosity of such an event for chosen disk and central BH mass.

Power Spacewalk on This Week @NASA - October 17, 2014

NASA Image and Video Library

2014-10-17

During an October 15 spacewalk outside the International Space Station – the second U.S. spacewalk in as many weeks – Expedition 41 Flight Engineers Reid Wiseman and Barry Wilmore of NASA, replaced a failed voltage regulation device to restore the station’s electrical power output to full capacity. The pair also relocated camera and TV equipment as part of a major reconfiguration to accommodate new docking adapters for use by U.S. commercial crew spacecraft in the next few years. Also, MAVEN’s “First Light”, Hubble finds extremely distant galaxy, Possible bonus destination for New Horizons, New information about volcanic activity on our moon and more!

Efficient entanglement distribution over 200 kilometers.

PubMed

Dynes, J F; Takesue, H; Yuan, Z L; Sharpe, A W; Harada, K; Honjo, T; Kamada, H; Tadanaga, O; Nishida, Y; Asobe, M; Shields, A J

2009-07-06

Here we report the first demonstration of entanglement distribution over a record distance of 200 km which is of sufficient fidelity to realize secure communication. In contrast to previous entanglement distribution schemes, we use detection elements based on practical avalanche photodiodes (APDs) operating in a self-differencing mode. These APDs are low-cost, compact and easy to operate requiring only electrical cooling to achieve high single photon detection efficiency. The self-differencing APDs in combination with a reliable parametric down-conversion source demonstrate that entanglement distribution over ultra-long distances has become both possible and practical. Consequently the outlook is extremely promising for real world entanglement-based communication between distantly separated parties.

Glimpsing Matter at the Brink

NASA Astrophysics Data System (ADS)

Morris, Mark R.

2004-04-01

Most astronomers are comfortable with the notion of a black hole at the center of our Galaxy, but defining and measuring its size is an extremely difficult matter, mostly because it is so small from our distant vantage point. In his Perspective, Morris discusses results reported in the same issue by Bower et al. on new measurements of the size of the radio-emitting region immediately surrounding the Galactic black hole. By observing at the shortest possible wavelengths with very long baseline interferometry, the authors have been able to resolve the intrinsic size of the black hole region in spite of the interstellar interference that has plagued previous attempts.

Intracranial meningeal hemangiopericytoma: Recurrences at the initial and distant intracranial sites and extraneural metastases to multiple organs

PubMed Central

WEI, GUANGQUAN; KANG, XIAOWEI; LIU, XIANPING; TANG, XING; LI, QINLONG; HAN, JUNTAO; YIN, HONG

2015-01-01

Regardless of the controversial pathogenesis, intracranial meningeal hemangiopericytoma (M-HPC) is a rare, highly cellular and vascularized mesenchymal tumor that is characterized by a high tendency for recurrence and extraneural metastasis, despite radical excision and postoperative radiotherapy. M-HPC shares similar clinical manifestations and radiological findings with meningioma, which causes difficulty in differentiation of this entity from those prognostically favorable mimics prior to surgery. Treatment of M-HPC, particularly in metastatic settings, remains a challenge. A case is described of primary M-HPC with recurrence at the initial and distant intracranial sites and extraneural multiple-organ metastases in a 36-year-old female. The metastasis of M-HPC was extremely extensive, and to the best of our knowledge this is the first case of M-HPC with delayed metastasis to the bilateral kidneys. The data suggests that preoperative computed tomography and magnetic resonance imaging could provide certain diagnostic clues and useful information for more optimal treatment planning. The results may imply that novel drugs, such as temozolomide and bevacizumab, as a component of multimodality therapy of M-HPC may deserve further investigation. PMID:26171177

Introgressive Hybridization between Anciently Diverged Lineages of Silene (Caryophyllaceae)

PubMed Central

Petri, Anna; Pfeil, Bernard E.; Oxelman, Bengt

2013-01-01

Hybridization has played a major role during the evolution of angiosperms, mediating both gene flow between already distinct species and the formation of new species. Newly formed hybrids between distantly related taxa are often sterile. For this reason, interspecific crosses resulting in fertile hybrids have rarely been described to take place after more than a few million years after divergence. We describe here the traces of a reproductively successful hybrid between two ancestral species of Silene, diverged for about six million years prior to hybridization. No extant hybrids between the two parental lineages are currently known, but introgression of the RNA polymerase gene NRPA2 provides clear evidence of a temporary and fertile hybrid. Parsimony reconciliation between gene trees and the species tree, as well as consideration of clade ages, help exclude gene paralogy and lineage sorting as alternative hypotheses. This may represent one of the most extreme cases of divergence between species prior to introgressive hybridization discovered yet, notably at a homoploid level. Although species boundaries are generally believed to be stable after millions of years of divergence, we believe that this finding may indicate that gene flow between distantly related species is merely largely undetected at present. PMID:23861793

Genetic structure of the crown-of-thorns seastar in the Pacific Ocean, with focus on Guam.

PubMed

Tusso, Sergio; Morcinek, Kerstin; Vogler, Catherine; Schupp, Peter J; Caballes, Ciemon F; Vargas, Sergio; Wörheide, Gert

2016-01-01

Population outbreaks of the corallivorous crown-of-thorns seastar (COTS), Acanthaster 'planci' L., are among the most important biological disturbances of tropical coral reefs. Over the past 50 years, several devastating outbreaks have been documented around Guam, an island in the western Pacific Ocean. Previous analyses have shown that in the Pacific Ocean, COTS larval dispersal may be geographically restricted to certain regions. Here, we assess the genetic structure of Pacific COTS populations and compared samples from around Guam with a number of distant localities in the Pacific Ocean, and focused on determining the degree of genetic structure among populations previously considered to be isolated. Using microsatellites, we document substantial genetic structure between 14 localities from different geographical regions in the Pacific Ocean. Populations from the 14 locations sampled were found to be structured in three significantly differentiated groups: (1) all locations immediately around Guam, as well as Kingman Reef and Swains Island; (2) Japan, Philippines, GBR and Vanuatu; and (3) Johnston Atoll, which was significantly different from all other localities. The lack of genetic differentiation between Guam and extremely distant populations from Kingman Reef and Swains Island suggests potential long-distance dispersal of COTS in the Pacific.

Learning in professionally 'distant' contexts: opportunities and challenges.

PubMed

Mausz, Justin; Tavares, Walter

2017-08-01

The changing nature of healthcare education and delivery is such that clinicians will increasingly find themselves practicing in contexts that are physically and/or conceptually different from the settings in which they were trained, a practice that conflicts on some level with socio-cultural theories of learning that emphasize learning in context. Our objective was therefore to explore learning in 'professionally distant' contexts. Using paramedic education, where portions of training occur in hospital settings despite preparing students for out-of-hospital work, fifty-three informants (11 current students, 13 recent graduates, 16 paramedic program faculty and 13 program coordinators/directors) took part in five semi-structured focus groups. Participants reflected on the value and role of hospital placements in paramedic student development. All sessions were audio recorded, transcribed verbatim and analyzed using inductive thematic analysis. In this context six educational advantages and two challenges were identified when using professionally distant learning environments. Learning could still be associated with features such as (a) engagement through "authenticity", (b) technical skill development, (c) interpersonal skill development, (d) psychological resilience, (e) healthcare system knowledge and (f) scaffolding. Variability in learning and misalignment with learning goals were identified as potential threats. Learning environments that are professionally distant from eventual practice settings may prove meaningful by providing learners with foundational and preparatory learning experiences for competencies that may be transferrable. This suggests that where learning occurs may be less important than how the experience contributes to the learner's development and the meaning or value he/she derives from it.

Laser space debris removal: now, not later

NASA Astrophysics Data System (ADS)

Phipps, Claude R.

2015-02-01

Small (1-10cm) debris in low Earth orbit (LEO) are extremely dangerous, because they spread the breakup cascade depicted in the movie "Gravity." Laser-Debris-Removal (LDR) is the only solution that can address both large and small debris. In this paper, we briefly review ground-based LDR, and discuss how a polar location can dramatically increase its effectiveness for the important class of sun-synchronous orbit (SSO) objects. No other solutions address the whole problem of large ( 1000cm, 1 ton) as well as small debris. Physical removal of small debris (by nets, tethers and so on) is impractical because of the energy cost of matching orbits. We also discuss a new proposal which uses a space-based station in low Earth orbit (LEO), and rapid, head-on interaction in 10- 40s rather than 4 minutes, with high-power bursts of 100ps, 355nm pulses from a 1.5m diameter aperture. The orbiting station employs "heat-capacity" laser mode with low duty cycle to create an adaptable, robust, dualmode system which can lower or raise large derelict objects into less dangerous orbits, as well as clear out the small debris in a 400-km thick LEO band. Time-average laser optical power is less than 15kW. The combination of short pulses and UV wavelength gives lower required energy density (fluence) on target as well as higher momentum coupling coefficient. This combination leads to much smaller mirrors and lower average power than the ground-based systems we have considered previously. Our system also permits strong defense of specific assets. Analysis gives an estimated cost of about 1k each to re-enter most small debris in a few months, and about 280k each to raise or lower 1-ton objects by 40km. We believe it can do this for 2,000 such large objects in about four years. Laser ablation is one of the few interactions in nature that propel a distant object without any significant reaction on the source.

Problems of Implementing SCORM in an Enterprise Distance Learning Architecture: SCORM Incompatibility across Multiple Web Domains.

ERIC Educational Resources Information Center

Engelbrecht, Jeffrey C.

2003-01-01

Delivering content to distant users located in dispersed networks, separated by firewalls and different web domains requires extensive customization and integration. This article outlines some of the problems of implementing the Sharable Content Object Reference Model (SCORM) in the Marine Corps' Distance Learning System (MarineNet) and extends…

Methodology for creating alloplasmic soybean lines by using Glycine tomentella as a maternal parent

USDA-ARS?s Scientific Manuscript database

Soybean breeders have not exploited the diversity of the 26 wild perennial species of the subgenus Glycine Willd. that are distantly related to soybean [G. max (L.) Merr.]. The objectives of this study were to introgress cytoplasmic and genetic diversity from G. tomentella PI 441001 (2n=78) into the...

How Historical Information Can Improve Extreme Value Analysis of Coastal Water Levels

NASA Astrophysics Data System (ADS)

Le Cozannet, G.; Bulteau, T.; Idier, D.; Lambert, J.; Garcin, M.

2016-12-01

The knowledge of extreme coastal water levels is useful for coastal flooding studies or the design of coastal defences. While deriving such extremes with standard analyses using tide gauge measurements, one often needs to deal with limited effective duration of observation which can result in large statistical uncertainties. This is even truer when one faces outliers, those particularly extreme values distant from the others. In a recent work (Bulteau et al., 2015), we investigated how historical information of past events reported in archives can reduce statistical uncertainties and relativize such outlying observations. We adapted a Bayesian Markov Chain Monte Carlo method, initially developed in the hydrology field (Reis and Stedinger, 2005), to the specific case of coastal water levels. We applied this method to the site of La Rochelle (France), where the storm Xynthia in 2010 generated a water level considered so far as an outlier. Based on 30 years of tide gauge measurements and 8 historical events since 1890, the results showed a significant decrease in statistical uncertainties on return levels when historical information is used. Also, Xynthia's water level no longer appeared as an outlier and we could have reasonably predicted the annual exceedance probability of that level beforehand (predictive probability for 2010 based on data until the end of 2009 of the same order of magnitude as the standard estimative probability using data until the end of 2010). Such results illustrate the usefulness of historical information in extreme value analyses of coastal water levels, as well as the relevance of the proposed method to integrate heterogeneous data in such analyses.

Blast from the Past Gives Clues About Early Universe

NASA Astrophysics Data System (ADS)

2009-10-01

Astronomers using the National Science Foundation's Very Large Array (VLA) radio telescope have gained tantalizing insights into the nature of the most distant object ever observed in the Universe -- a gigantic stellar explosion known as a Gamma Ray Burst (GRB). The explosion was detected on April 23 by NASA's Swift satellite, and scientists soon realized that it was more than 13 billion light-years from Earth. It represents an event that occurred 630 million years after the Big Bang, when the Universe was only four percent of its current age of 13.7 billion years. This explosion provides an unprecedented look at an era when the Universe was very young and also was undergoing drastic changes. The primal cosmic darkness was being pierced by the light of the first stars and the first galaxies were beginning to form. The star that exploded in this event was a member of one of these earliest generations of stars," said Dale Frail of the National Radio Astronomy Observatory. Astronomers turned telescopes from around the world to study the blast, dubbed GRB 090423. The VLA first looked for the object the day after the discovery, detected the first radio waves from the blast a week later, then recorded changes in the object until it faded from view more than two months later. "It's important to study these explosions with many kinds of telescopes. Our research team combined data from the VLA with data from X-ray and infrared telescopes to piece together some of the physical conditions of the blast," said Derek Fox of Pennsylvania State University. "The result is a unique look into the very early Universe that we couldn't have gotten any other way," he added. The scientists concluded that the explosion was more energetic than most GRBs, was a nearly-spherical blast, and that it expanded into a tenuous and relatively uniform gaseous medium surrounding the star. Astronomers suspect that the very first stars in the Universe were very different -- brighter, hotter, and more massive -- from those that formed later. They hope to find evidence for these giants by observing objects as distant as GRB 090423 or more distant. "The best way to distinguish these distant, early-generation stars is by studying their explosive deaths, as supernovae or Gamma Ray Bursts," said Poonam Chandra, of the Royal Military College of Canada, and leader of the research team. While the data on GRB 090423 don't indicate that it resulted from the death of such a monster star, new astronomical tools are coming that may reveal them. "The Atacama Large Millimeter/submillimeter Array (ALMA), will allow us to pick out these very-distant GRBs more easily so we can target them for intense followup observations. The Expanded Very Large Array, with much greater sensitivity than the current VLA, will let us follow these blasts much longer and learn much more about their energies and environments. We'll be able to look back even further in time," Frail said. Both ALMA and the EVLA are scheduled for completion in 2012. Chandra, Frail and Fox worked with Shrinivas Kulkarni of Caltech, Edo Berger of Harvard University, S. Bradley Cenko of the University of California at Berkeley, Douglas C.-J. Bock of the Combined Array for Research in Millimeter-wave Astronomy in California, and Fiona Harrison and Mansi Kasliwal of Caltech. The scientists described their research in a paper submitted to the Astrophysical Journal Letters.

Comet Halley passes the halfway mark. Very distant image obtained with the ESO NTT.

NASA Astrophysics Data System (ADS)

1994-02-01

Eight years after the passage of Comet Halley in early 1986, astronomers at the European Southern Observatory have succeeded in obtaining an image [1] of this famous object at a distance of no less than 2,820 million km from the Sun. The comet is now about as far away as giant planet Uranus. It recently passed the halfway mark towards the most distant point of its very elongated 76-year orbit. The image shows the 6 x 15 km avocado-shaped nucleus as an extremely faint point of light without any surrounding dust cloud. It appears that the surface is now completely frozen and the comet has ceased to emit dust and gas. This observation was made with the ESO 3.58 metre New Technology Telescope (NTT). It is by far the faintest and most distant image ever recorded of this comet. A DIFFICULT OBSERVATION The new Halley image was obtained in the course of an observational programme by a small group of astronomers [2], aimed at the investigation of distant solar system objects. The observation was difficult to perform and is close to the limit of what is possible, even with the NTT, one of the technologically most advanced astronomical telescopes. In fact, this observation may be compared to viewing a black golfball, used during a late evening game, from a distance of 12,000 km. At Halley's present, very large distance from the Sun, the intensity of the solar light is over 350 times fainter than here on Earth. The surface of the cometary nucleus is very dark; it reflects only 4 % of the infalling sunlight. The amount of light received from Halley is therefore extremely small: the recorded star-like image of the nucleus is about 160 million times fainter than the faintest star that can be seen with the unaided eye. A long exposure was needed to catch enough light to show the object; even with the very sensitive SuSI CCD camera at the NTT, the shutter had to be kept open for a total of 3 hours 45 minutes. During this time, of the order of 9000 photons from Comet Halley were registered. The extreme faintness of its image is illustrated by the fact that almost 1 million, or 100 times as many photons were simultaneously received in this direction from the luminous atmosphere of the Earth. They must be carefully "subtracted", before the comet can be seen. There is another complication. Due to the motions of the comet and the Earth, the direction to the comet (as seen against the stars in the background) continuously changes during the observation. The movement of the telescope must therefore be accurately offset to "follow" the motion of the comet in order to keep the sparse photons falling on the same spot of the detector during the long exposure. IS HALLEY NOW FROZEN? The measured brightness of the Halley image (visual magnitude 26.5 +- 0.2) closely corresponds to what would be expected, if it results from sunlight being reflected from the nucleus alone. This indicates that there is little, if any, dust left around the nucleus and it must be assumed that its surface layers are now completely frozen. The observation therefore shows that nothing is left of the great mass of dusty material, estimated at 1 million tonnes, that was thrown out during the completely unexpected outburst observed at ESO in February 1991. Nevertheless, the astronomers intend to continue to monitor the behaviour of Halley during the next years - it cannot be excluded that this comet may be good for another surprise! FUTURE OBSERVATIONS WITH THE VLT Comet Halley will continue to move outwards through the solar system at decreasing speed. Thirty years from now it reaches the turning point (the "aphelion") of its elongated orbit, almost 5,300 million kilometres from the Sun. Although the light reflected from its nucleus will then be 15 times fainter than at the present time, it should still be possible to register its image with one of the 8.2 metre unit telescopes of the ESO Very Large Telescope (VLT) during exposures of only a few hours' duration. Comet Halley's next return to our neighbourhood will take place in the year 2061. 1 A B/W photo accompanies this Press Release. 2 The members are Olivier Hainaut and Richard West (ESO), Brian Marsden (Harvard-Smithsonian Center for Astrophysics, Cambridge, Massachusetts, U.S.A.) and Karen Meech (Institute for Astronomy, Honolulu, Hawaii, U.S.A.). The Halley observation is also described on a Circular of the International Astronomical Union, published today. 3 See ESO Press Release 03/91 of 22 February 1991. FIGURE CAPTION ESO PR PHOTO 04/94-1: COMET HALLEY AT 2,820 MILLION KM This negative photo shows the faint image of periodic comet Halley (in the circle) at the record heliocentric distance 18.82 AU (= 2,820 million km, about the distance of Uranus). It was obtained with the SuSI CCD camera at the ESO 3.58 m New Technology Telescope (NTT) during the night of January 10--11, 1994. Nine individual exposures, each lasting 25 minutes, were used to produce this picture. They were cleaned to remove various sky and instrumental noise, shifted according to the predicted motion of the comet and then co-added. This ensures that all recorded light from the comet is concentrated in one place. At the same time, the images of the other objects that do not share the motion of the comet, are not superposed and will therefore be seen as long trails. The non-uniformities of these trails arise because of varying sky conditions and also due to the time intervals between the individual exposures. In addition to the comet, the picture contains the images of three very different types of objects: stars with relatively sharp trails (e.g. the comparatively bright one, just below the comet image), several extended (diffuse) galaxies, and an artificial Earth satellite which happened to cross the field during one of the exposures (its trail extends from the middle of the left edge to the lower edge). The measured magnitude of P/Halley is V = 26.5 +-0.2. The position in the sky is less than 1 arcsec from that predicted on the basis of the comet's very well-determined orbit. Technical information: The CCD frames were cleaned of cosmics and flat-fielded, but they were neither filtered, nor smoothed. Total exposure time: 13,500 seconds. The seeing varied from 0.6 - 0.9 arcsec. One pixel = 0.13 arcsec. Field size: 310 x 430 pixels or 40 x 56 arcsec. North is up and East is to the left. This photo (ESO PR PHOTO 04/94-1) accompanies ESO Press Release 04/94 and may be reproduced, if credit is given to the European Southern Observatory.

Prediction of stellar occultations by distant solar system bodies in the Gaia era

NASA Astrophysics Data System (ADS)

Desmars, Josselin; Camargo, Julio; Sicardy, Bruno; Braga-Ribas, Felipe; Vieira-Martins, Roberto; Assafin, Marcelo; Bérard, Diane; Benedetti-Rossi, Gustavo

2018-04-01

Stellar occultations are a unique technique to access physical characteristics of distant solar system objects from the ground. They allow the measure of the size and the shape at kilometric level, the detection of tenuous atmospheres (few nanobars), and the investigation of close vicinity (satellites, rings) of Transneptunian objects and Centaurs. This technique is made successful thanks to accurate predictions of occultations. Accuracy of the predictions depends on the uncertainty in the position of the occulted star and the object's orbit. The Gaia stellar catalogue (Gaia Collaboration (2017)) now allows to get accurate astrometric stellar positions (to the mas level). The main uncertainty remains on the orbit. In this context, we now take advantage of the NIMA method (Desmars et al.(2015)) for the orbit determination and of the Gaia DR1 catalogue for the astrometry. In this document, we show how the orbit determination is improved by reducing current and some past observations with Gaia DR1. Moreover, we also use more than 45 past positive occultations observed in the 2009-2017 period to derive very accurate astrometric positions only depending on the position of the occulted stars (about few mas with Gaia DR1). We use the case of (10199) Chariklo as an illustration. The main limitation lies in the imprecision of the proper motions which is going to be solved by the Gaia DR2 release.

Visible and infrared investigations of planet-crossing asteroids and outer solar system objects

NASA Technical Reports Server (NTRS)

Tholen, David J.

1991-01-01

The project is supporting lightcurve photometry, colorimetry, thermal radiometry, and astrometry of selected asteroids. Targets include the planet-crossing population, particularly Earth approachers, which are believed to be the immediate source of terrestrial meteorites, future spacecraft targets, and those objects in the outer belt, primarily the Hilda and Trojan populations, that are dynamically isolated from the main asteroid belt. Goals include the determination of population statistics for the planet-crossing objects, the characterization of spacecraft targets to assist in encounter planning and subsequent interpretation of the data, a comparison of the collisional evolution of dynamically isolated Hilda and Trojan populations with the main belt, and the determination of the mechanism driving the activity of the distant object 2060 Chiron.

Primary Tumor Necrosis Predicts Distant Control in Locally Advanced Soft-Tissue Sarcomas After Preoperative Concurrent Chemoradiotherapy

DOE Office of Scientific and Technical Information (OSTI.GOV)

MacDermed, Dhara M.; Miller, Luke L.; Peabody, Terrance D.

Purpose: Various neoadjuvant approaches have been evaluated for the treatment of locally advanced soft-tissue sarcomas. This retrospective study describes a uniquely modified version of the Eilber regimen developed at the University of Chicago. Methods and Materials: We treated 34 patients (28 Stage III and 6 Stage IV) with locally advanced soft-tissue sarcomas of an extremity between 1995 and 2008. All patients received preoperative therapy including ifosfamide (2.5 g/m2 per day for 5 days) with concurrent radiation (28 Gy in 3.5-Gy daily fractions), sandwiched between various chemotherapy regimens. Postoperatively, 47% received further adjuvant chemotherapy. Results: Most tumors (94%) were Grade 3,more » and all were T2b, with a median size of 10.3 cm. Wide excision was performed in 29 patients (85%), and 5 required amputation. Of the resected tumor specimens, 50% exhibited high (>=90%) treatment-induced necrosis and 11.8% had a complete pathologic response. Surgical margins were negative in all patients. The 5-year survival rate was 42.3% for all patients and 45.2% for Stage III patients. For limb-preservation patients, the 5-year local control rate was 89.0% and reoperation was required for wound complications in 17.2%. The 5-year freedom-from-distant metastasis rate was 53.4% (Stage IV patients excluded), and freedom from distant metastasis was superior if treatment-induced tumor necrosis was 90% or greater (84.6% vs. 19.9%, p = 0.02). Conclusions: This well-tolerated concurrent chemoradiotherapy approach yields excellent rates of limb preservation and local control. The resulting treatment-induced necrosis rates are predictive of subsequent metastatic risk, and this information may provide an opportunity to guide postoperative systemic therapies.« less

Microseismic Monitoring of Stimulating Shale Gas Reservoir in SW China: 2. Spatial Clustering Controlled by the Preexisting Faults and Fractures

NASA Astrophysics Data System (ADS)

Chen, Haichao; Meng, Xiaobo; Niu, Fenglin; Tang, Youcai; Yin, Chen; Wu, Furong

2018-02-01

Microseismic monitoring is crucial to improving stimulation efficiency of hydraulic fracturing treatment, as well as to mitigating potential induced seismic hazard. We applied an improved matching and locating technique to the downhole microseismic data set during one treatment stage along a horizontal well within the Weiyuan shale gas play inside Sichuan Basin in SW China, resulting in 3,052 well-located microseismic events. We employed this expanded catalog to investigate the spatiotemporal evolution of the microseismicity in order to constrain migration of the injected fluids and the associated dynamic processes. The microseismicity is generally characterized by two distinctly different clusters, both of which are highly correlated with the injection activity spatially and temporarily. The distant and well-confined cluster (cluster A) is featured by relatively large-magnitude events, with 40 events of M -1 or greater, whereas the cluster in the immediate vicinity of the wellbore (cluster B) includes two apparent lineations of seismicity with a NE-SW trending, consistent with the predominant orientation of natural fractures. We calculated the b-value and D-value, an index of fracture complexity, and found significant differences between the two seismicity clusters. Particularly, the distant cluster showed an extremely low b-value ( 0.47) and D-value ( 1.35). We speculate that the distant cluster is triggered by reactivation of a preexisting critically stressed fault, whereas the two lineations are induced by shear failures of optimally oriented natural fractures associated with fluid diffusion. In both cases, the spatially clustered microseismicity related to hydraulic stimulation is strongly controlled by the preexisting faults and fractures.

Galaxies Gather at Great Distances

NASA Technical Reports Server (NTRS)

2006-01-01

[figure removed for brevity, see original site] Distant Galaxy Cluster Infrared Survey Poster [figure removed for brevity, see original site] [figure removed for brevity, see original site] Bird's Eye View Mosaic Bird's Eye View Mosaic with Clusters [figure removed for brevity, see original site] [figure removed for brevity, see original site] [figure removed for brevity, see original site] 9.1 Billion Light-Years 8.7 Billion Light-Years 8.6 Billion Light-Years

Astronomers have discovered nearly 300 galaxy clusters and groups, including almost 100 located 8 to 10 billion light-years away, using the space-based Spitzer Space Telescope and the ground-based Mayall 4-meter telescope at Kitt Peak National Observatory in Tucson, Ariz. The new sample represents a six-fold increase in the number of known galaxy clusters and groups at such extreme distances, and will allow astronomers to systematically study massive galaxies two-thirds of the way back to the Big Bang.

A mosaic portraying a bird's eye view of the field in which the distant clusters were found is shown at upper left. It spans a region of sky 40 times larger than that covered by the full moon as seen from Earth. Thousands of individual images from Spitzer's infrared array camera instrument were stitched together to create this mosaic. The distant clusters are marked with orange dots.

Close-up images of three of the distant galaxy clusters are shown in the adjoining panels. The clusters appear as a concentration of red dots near the center of each image. These images reveal the galaxies as they were over 8 billion years ago, since that's how long their light took to reach Earth and Spitzer's infrared eyes.

These pictures are false-color composites, combining ground-based optical images captured by the Mosaic-I camera on the Mayall 4-meter telescope at Kitt Peak, with infrared pictures taken by Spitzer's infrared array camera. Blue and green represent visible light at wavelengths of 0.4 microns and 0.8 microns, respectively, while red indicates infrared light at 4.5 microns.

Kitt Peak National Observatory is part of the National Optical Astronomy Observatory in Tuscon, Ariz.

Who Cares about Caring in Early Childhood Teacher Education Programs?

ERIC Educational Resources Information Center

McNamee, Abigail; Mercurio, Mia; Peloso, Jeanne M.

2007-01-01

The ability to care for oneself, near and distant others, animals, plants, human-made objects, and even ideas is an antidote for violence in its many forms as experienced in childhood as well as adulthood. This article makes a case for facilitating the development of the ability to care as children develop. The authors emphasize the importance of…

Human Papillomavirus Vaccine and Pap Tests on College Campuses: How Do Historically Black Colleges and Universities (HSBCUs) Measure Up?

ERIC Educational Resources Information Center

Barnett, Kierra S.; Shoben, Abigail B.; McRee, Annie-Laurie; Reiter, Paul L.; Paskett, Electra D.; Katz, Mira L.

2016-01-01

Objective: The availability of cervical cancer prevention services at college health centers was compared between historically black colleges and universities (HBCUs) and non-HBCUs. Methods: Four-year, non-primarily distant learning colleges, matching HBCUs with randomly selected non-HBCUs within the same states (N = 136) were examined. Data were…

Dynamics, Chemical Abundances, and ages of Globular Clusters in the Virgo Cluster of Galaxies

NASA Astrophysics Data System (ADS)

Guhathakurta, Puragra; NGVS Collaboration

2018-01-01

We present a study of the dynamics, metallicities, and ages of globular clusters (GCs) in the Next Generation Virgo cluster Survey (NGVS), a deep, multi-band (u, g, r, i, z, and Ks), wide-field (104 deg2) imaging survey carried out using the 3.6-m Canada-France-Hawaii Telescope and MegaCam imager. GC candidates were selected from the NGVS survey using photometric and image morphology criteria and these were followed up with deep, medium-resolution, multi-object spectroscopy using the Keck II 10-m telescope and DEIMOS spectrograph. The primary spectroscopic targets were candidate GC satellites of dwarf elliptical (dE) and ultra-diffuse galaxies (UDGs) in the Virgo cluster. While many objects were confirmed as GC satellites of Virgo dEs and UDGs, many turned out to be non-satellites based on their radial velocity and/or positional mismatch any identifiable Virgo cluster galaxy. We have used a combination of spectral characteristics (e.g., presence of absorption vs. emission lines), new Gaussian mixture modeling of radial velocity and sky position data, and a new extreme deconvolution analysis of ugrizKs photometry and image morphology, to classify all the objects in our sample into: (1) GC satellites of dE galaxies, (2) GC satellites of UDGs, (3) intra-cluster GCs (ICGCs) in the Virgo cluster, (4) GCs in the outer halo of the central cluster galaxy M87, (5) foreground Milky Way stars, and (6) distant background galaxies. We use these data to study the dynamics and dark matter content of dE and UDGs in the Virgo cluster, place important constraints on the nature of dE nuclei, and study the origin of ICGCs versus GCs in the remote M87 halo.We are grateful for financial support from the NSF and NASA/STScI.

Super-resolution optical telescopes with local light diffraction shrinkage

PubMed Central

Wang, Changtao; Tang, Dongliang; Wang, Yanqin; Zhao, Zeyu; Wang, Jiong; Pu, Mingbo; Zhang, Yudong; Yan, Wei; Gao, Ping; Luo, Xiangang

2015-01-01

Suffering from giant size of objective lenses and infeasible manipulations of distant targets, telescopes could not seek helps from present super-resolution imaging, such as scanning near-field optical microscopy, perfect lens and stimulated emission depletion microscopy. In this paper, local light diffraction shrinkage associated with optical super-oscillatory phenomenon is proposed for real-time and optically restoring super-resolution imaging information in a telescope system. It is found that fine target features concealed in diffraction-limited optical images of a telescope could be observed in a small local field of view, benefiting from a relayed metasurface-based super-oscillatory imaging optics in which some local Fourier components beyond the cut-off frequency of telescope could be restored. As experimental examples, a minimal resolution to 0.55 of Rayleigh criterion is obtained, and imaging complex targets and large targets by superimposing multiple local fields of views are demonstrated as well. This investigation provides an access for real-time, incoherent and super-resolution telescopes without the manipulation of distant targets. More importantly, it gives counterintuitive evidence to the common knowledge that relayed optics could not deliver more imaging details than objective systems. PMID:26677820

A Hubble Diagram of Distant Type IA Supernovae

NASA Astrophysics Data System (ADS)

Hamuy, M.; Phillips, M. M.; Suntzeff, N. B.; Aviles, R.; Maza, J.

1993-12-01

Due to their extreme luminosities at maximum light, type Ia supernovae (SNe Ia) have long been considered among the most attractive cosmological standard candles. Although nearly all work to date has been devoted to attempts to use these objects to determine the local rate of expansion of the universe (Ho), SNe Ia also provide one of the few direct techniques for measuring the deceleration parameter qo. However, in a recent study of nine well-observed events based largely on data obtained at CTIO, Phillips (1993, ApJ, 413, L105) found clear evidence for a significant intrinsic dispersion in SNe Ia absolute magnitudes amounting to ~ 0.8 mag in B, ~ 0.7 mag in V, and ~ 0.5 mag in I. Such a range in peak luminosity could introduce a subtantial Malmquist bias into searches for distant (z <= 0.3) SNe Ia which, if uncorrected, could lead to an erroneous value of qo. In this paper we present the Hubble diagram for 13 SNe Ia discovered and observed in the course of the Calan/Tololo Supernova Survey. This sample, which covers the redshift range 0.01 <= z <= 0.1, provides unequivocal evidence for an intrinsic spread in the peak luminosities of type Ia events. The data also confirm Phillips' conclusion that the maximum-light luminosity is strongly correlated with the initial decline rate of the B light curve. Interestingly, the most luminous SNe in our sample all occurred in spiral galaxies, which is true for Phillips' sample of nearby SNe Ia as well. This is opposite to what one would expect if dust extinction were important. These findings are consistent with recent speculations that the progenitors of SNe Ia are white dwarfs covering a range of masses, and also suggest that the brightest events may be found in galaxies which are still actively forming stars. The implications for the use of SNe Ia to measure qo are briefly discussed. This research has been supported by Grant 92/0312 from Fondo Nacional de Ciencias y Tecnología (FONDECYT-Chile).

Hazard-Rate Analysis and Patterns of Recurrence in Early Stage Melanoma: Moving towards a Rationally Designed Surveillance Strategy

PubMed Central

Scheri, Randall P.; Pruitt, Scott K.; Herndon, James E.; Marcello, Jennifer; Tyler, Douglas S.; Abernethy, Amy P.

2013-01-01

Background While curable at early stages, few treatment options exist for advanced melanoma. Currently, no consensus exists regarding the optimal surveillance strategy for patients after resection. The objectives of this study were to identify patterns of metastatic recurrence, to determine the influence of metastatic site on survival, and to identify high-risk periods for recurrence. Methods A retrospective review of the Duke Melanoma Database from 1970 to 2004 was conducted that focused on patients who were initially diagnosed without metastatic disease. The time to first recurrence was computed from the date of diagnosis, and the associated hazard function was examined to determine the peak risk period of recurrence. Metastatic sites were coded by the American Joint Committee on Cancer (AJCC) system including local skin, distant skin and nodes (M1a), lung (M1b), and other distant (M1c). Results Of 11,615 patients initially diagnosed without metastatic disease, 4616 (40%) had at least one recurrence. Overall the risk of initial recurrence peaked at 12 months. The risk of initial recurrence at the local skin, distant skin, and nodes peaked at 8 months, and the risk at lung and other distant sites peaked at 24 months. Patients with a cutaneous or nodal recurrence had improved survival compared to other recurrence types. Conclusions The risk of developing recurrent melanoma peaked at one year, and the site of first recurrence had a significant impact on survival. Defining the timing and expected patterns of recurrence will be important in creating an optimized surveillance strategy for this patient population. PMID:23516415

Dwarfs in the Deepest Fields at Noon: Studying Size and Shape of Low-mass Galaxies out to z 3 in Five HST Legacy Fields

NASA Astrophysics Data System (ADS)

Guo, Yicheng

2017-08-01

Galaxies with stellar mass 100x-1000x times smaller than our Milky Way (hereafter dwarf galaxies or DGs) are important for understanding galaxy formation and evolution by being the most sensitive probes of both the macro-physics of dark matter halos and the micro-physics of the different physical mechanisms that regulate star formation and shape galaxies. Currently, however, observations of distant DGs have been hampered by small samples and poor quality due to their faintness. We propose an archival study of the size, morphology, and structures of DGs out to z 3.0 by combining the archived data from five of the deepest regions that HST has ever observed: eXtreme Deep Field (XDF, updated from HUDF) and the Hubble Legacy Fields (HLFs). Our program would be the first to advance the morphology studies of DGs to the Cosmic Noon (z 2), and hence place unprecedented constraints on models of galaxy structure formation. Equally important is the data product of our program: multi-wavelength photometry and morphology catalogs for all detected galaxies in these fields. These catalogs would be a timely treasure for the public to prepare for the coming JWST era by providing detailed information of small, faint, but important objects in some deepest HST fields for JWST observations.

IRAS 14348-1447, an Ultraluminous Pair of Colliding, Gas-Rich Galaxies: The Birth of a Quasar?

PubMed

Sanders, D B; Scoville, N Z; Soifer, B T

1988-02-05

Ground-based observations of the object IRAS 14348-1447, which was discovered with the Infrared Astronomical Satellite, show that it is an extremely luminous colliding galaxy system that emits more than 95 percent of its energy at far-infrared wavelengths. IRAS 14348-1447, which is receeding from the sun at 8 percent of the speed of light, has a bolometric luminosity more than 100 times larger than that of our galaxy, and is therefore as luminous as optical quasars. New optical, infrared, and spectroscopic measurements suggest that the dominant luminosity source is a dustenshrouded quasar. The fuel for the intense activity is an enormous supply of molecular gas. Carbon monoxide emission has been detected at a wavelength of 2.6 millimeters by means of a new, more sensitive receiver recently installed on the 12-meter telescope of the National Radio Astronomy Observatory. IRAS 14348-1447 is the most distant and luminous source of carbon monoxide line emission yet detected. The derived mass of interstellar molecular hydrogen is 6 x 10(10) solar masses. This value is approximately 20 times that of the molecular gas content of the Milky Way and is similar to the largest masses of atomic hydrogen found in galaxies. A large mass of molecular gas may be a prerequisite for the formation of quasars during strong galactic collisions.

The Search for RR Lyrae Variables in the Dark Energy Survey

NASA Astrophysics Data System (ADS)

Nielsen, Chandler; Marshall, Jennifer L.; Long, James

2017-01-01

RR Lyrae variables are stars with a characteristic relationship between magnitude and phase and whose distances can be easily determined, making them extremely valuable in mapping and analyzing galactic substructure. We present our method of searching for RR Lyrae variable stars using data extracted from the Dark Energy Survey (DES). The DES probes for stars as faint as i = 24.3. Finding such distant RR Lyrae allows for the discovery of objects such as dwarf spheroidal tidal streams and dwarf galaxies; in fact, at least one RR Lyrae has been discovered in each of the probed dwarf spheroidal galaxies orbiting the Milky Way (Baker & Willman 2015). In turn, these discoveries may ultimately resolve the well-known missing satellite problem, in which theoretical simulations predict many more dwarf satellites than are observed in the local Universe. Using the Lomb-Scargle periodogram to determine the period of the star being analyzed, we could display the relationship between magnitude and phase and visually determine if the star being analyzed was an RR Lyrae. We began the search in frequently observed regions of the DES footprint, known as the supernova fields. We then moved our search to known dwarf galaxies found during the second year of the DES. Unfortunately, we did not discover RR Lyrae in the probed dwarf galaxies; this method should be tried again once more observations are taken in the DES.

The Euclid mission design

NASA Astrophysics Data System (ADS)

Racca, Giuseppe D.; Laureijs, René; Stagnaro, Luca; Salvignol, Jean-Christophe; Lorenzo Alvarez, José; Saavedra Criado, Gonzalo; Gaspar Venancio, Luis; Short, Alex; Strada, Paolo; Bönke, Tobias; Colombo, Cyril; Calvi, Adriano; Maiorano, Elena; Piersanti, Osvaldo; Prezelus, Sylvain; Rosato, Pierluigi; Pinel, Jacques; Rozemeijer, Hans; Lesna, Valentina; Musi, Paolo; Sias, Marco; Anselmi, Alberto; Cazaubiel, Vincent; Vaillon, Ludovic; Mellier, Yannick; Amiaux, Jérôme; Berthé, Michel; Sauvage, Marc; Azzollini, Ruyman; Cropper, Mark; Pottinger, Sabrina; Jahnke, Knud; Ealet, Anne; Maciaszek, Thierry; Pasian, Fabio; Zacchei, Andrea; Scaramella, Roberto; Hoar, John; Kohley, Ralf; Vavrek, Roland; Rudolph, Andreas; Schmidt, Micha

2016-07-01

Euclid is a space-based optical/near-infrared survey mission of the European Space Agency (ESA) to investigate the nature of dark energy, dark matter and gravity by observing the geometry of the Universe and on the formation of structures over cosmological timescales. Euclid will use two probes of the signature of dark matter and energy: Weak gravitational Lensing, which requires the measurement of the shape and photometric redshifts of distant galaxies, and Galaxy Clustering, based on the measurement of the 3-dimensional distribution of galaxies through their spectroscopic redshifts. The mission is scheduled for launch in 2020 and is designed for 6 years of nominal survey operations. The Euclid Spacecraft is composed of a Service Module and a Payload Module. The Service Module comprises all the conventional spacecraft subsystems, the instruments warm electronics units, the sun shield and the solar arrays. In particular the Service Module provides the extremely challenging pointing accuracy required by the scientific objectives. The Payload Module consists of a 1.2 m three-mirror Korsch type telescope and of two instruments, the visible imager and the near-infrared spectro-photometer, both covering a large common field-of-view enabling to survey more than 35% of the entire sky. All sensor data are downlinked using K-band transmission and processed by a dedicated ground segment for science data processing. The Euclid data and catalogues will be made available to the public at the ESA Science Data Centre.

Principles of treatment for mammary gland tumors.

PubMed

Novosad, C Andrew

2003-05-01

The mammary glands are frequent locations for the development of tumors. In the dog and cat, early detection and rapid therapy are necessary to prevent both local and distant metastasis. In the dog, this disease can have a range of biologic behaviors, whereas in the cat it is almost always an extremely aggressive disease. Treatment options depend on tumor staging and can include surgery, radiation therapy, chemotherapy, or a combination. As we become better at early diagnosis and are able to implement aggressive therapy, we are becoming more and more successful in the treatment of this disease. In the following article, we will discuss current thoughts surrounding the diagnosis and treatment options for both canine and feline mammary gland tumors.

XMM-Newton X-ray and HST weak gravitational lensing study of the extremely X-ray luminous galaxy cluster Cl J120958.9+495352 ( z = 0.902)

DOE PAGES

Tholken, Sophia; Schrabback, Tim; Reiprich, Thomas H.; ...

2018-03-05

Here, observations of relaxed, massive, and distant clusters can provide important tests of standard cosmological models, for example by using the gas mass fraction. To perform this test, the dynamical state of the cluster and its gas properties have to be investigated. X-ray analyses provide one of the best opportunities to access this information and to determine important properties such as temperature profiles, gas mass, and the total X-ray hydrostatic mass. For the last of these, weak gravitational lensing analyses are complementary independent probes that are essential in order to test whether X-ray masses could be biased.

Lymphoepithelioma-like Carcinoma of the Breast: A Case Report

PubMed Central

Top, Ömer Erdinç; Vardar, Enver; Yağcı, Ayşe; Deniz, Senem; Öztürk, Rafet; Zengel, Baha

2014-01-01

Lymphoepithelioma-like carcinoma carries similar histopathological features with lymphoepithelioma typically located in the nasopharynx. Lymphoepithelioma-like carcinoma of the breast can be mistaken for breast lymphoma or medullary carcinoma due to the undifferentiated appearance of tumor cells and presence of prominent lymphoid component. Lymphoepithelioma-like carcinoma is rare, and the similarity between medullary carcinoma of the breast makes it difficult to distinguish these two tumors. In the presented case, neither lymph node nor distant metastases were detected. Breast lymphoepithelioma-like carcinoma is extremely rare with only 21 reported cases in the literature. Herein we present a 59-year-old woman with lymphoepithelioma-like carcinoma of the breast along with the cases previously published in the literature. PMID:28331666

Proximal-type epithelioid sarcoma - Case report*

PubMed Central

dos Santos, Luciana Mendes; Nogueira, Lisiane; Matsuo, Christiane Yuri; Talhari, Carolina; Santos, Mônica

2013-01-01

Epithelioid sarcoma, first described by Enzinger in 1970, is a rare soft-tissue sarcoma typically presenting as a subcutaneous or deep dermal mass in distal portions of the extremities of adolescents and young adults. In 1997, Guillou et al. described a different type of epithelioid sarcoma, called proximal-type epithelioid sarcoma, which is found mostly in the pelvic and perineal regions and genital tracts of young to middle-aged adults. It is characterized by a proliferation of epithelioid-like cells with rhabdoid features and the absence of a granuloma-like pattern. In this paper we present a case of proximal-type epithelioid sarcoma with an aggressive clinical course, including distant metastasis and death nine months after diagnosis. PMID:23793215

XMM-Newton X-ray and HST weak gravitational lensing study of the extremely X-ray luminous galaxy cluster Cl J120958.9+495352 ( z = 0.902)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tholken, Sophia; Schrabback, Tim; Reiprich, Thomas H.

Here, observations of relaxed, massive, and distant clusters can provide important tests of standard cosmological models, for example by using the gas mass fraction. To perform this test, the dynamical state of the cluster and its gas properties have to be investigated. X-ray analyses provide one of the best opportunities to access this information and to determine important properties such as temperature profiles, gas mass, and the total X-ray hydrostatic mass. For the last of these, weak gravitational lensing analyses are complementary independent probes that are essential in order to test whether X-ray masses could be biased.

Mutually unbiased bases in six dimensions: The four most distant bases

DOE Office of Scientific and Technical Information (OSTI.GOV)

Raynal, Philippe; Lue Xin; Englert, Berthold-Georg

2011-06-15

We consider the average distance between four bases in six dimensions. The distance between two orthonormal bases vanishes when the bases are the same, and the distance reaches its maximal value of unity when the bases are unbiased. We perform a numerical search for the maximum average distance and find it to be strictly smaller than unity. This is strong evidence that no four mutually unbiased bases exist in six dimensions. We also provide a two-parameter family of three bases which, together with the canonical basis, reach the numerically found maximum of the average distance, and we conduct a detailedmore » study of the structure of the extremal set of bases.« less

Genes from scratch--the evolutionary fate of de novo genes.

PubMed

Schlötterer, Christian

2015-04-01

Although considered an extremely unlikely event, many genes emerge from previously noncoding genomic regions. This review covers the entire life cycle of such de novo genes. Two competing hypotheses about the process of de novo gene birth are discussed as well as the high death rate of de novo genes. Despite the high death rate, some de novo genes are retained and remain functional, even in distantly related species, through their integration into gene networks. Further studies combining gene expression with ribosome profiling in multiple populations across different species will be instrumental for an improved understanding of the evolutionary processes operating on de novo genes. Copyright © 2015 The Author. Published by Elsevier Ltd.. All rights reserved.

Wink of a Star

NASA Image and Video Library

2017-07-19

NASA's New Horizons team trained mobile telescopes on an unnamed star (circled) from a remote area of Argentina on July 17, 2017. A Kuiper Belt object 4.1 billion miles from Earth -- known as 2014 MU69 -- briefly blocked the light from the background star, in what's known as an occultation. The time difference between frames is 200 milliseconds, or 0.2 seconds. This data will help scientists better measure the shape, size and environment around the object. The New Horizons spacecraft will fly by this ancient relic of solar system formation on Jan. 1, 2019. It will be the most distant object ever explored by a spacecraft. A video is available at https://photojournal.jpl.nasa.gov/catalog/PIA21865

Space Science

NASA Image and Video Library

1978-12-01

The Andromeda Galaxy, also known as M31 since it is the 31st object on Messier's list of diffuse sky objects, is the nearest large galaxy to our own Milky Way galaxy. Our galaxy is thought to look much like Andromeda, but it is about four times as massive as the Milky Way. Together these two galaxies dominate the Local Group of galaxies. The diffused light from Andromeda is caused by hundreds of billions of stars that compose it. The several distinct stars that surround Andromeda's image are actually stars in our galaxy that are well in front of the background object. Andromeda is so distant that it takes approximately two millions years for light to reach us from there.

Synergetic Paradigm of Geographical Science

ERIC Educational Resources Information Center

Gorbanyov, Vladimir A.

2016-01-01

It is shown that in the last decades, geography has expanded so much, that it has lost its object of study. It was not clear, what the geographical science does, and, as a consequence, households have an extremely low level of geographical cultures and geographical education. Each geography is extremely isolated, has its own object of study.…

Ranking of European Capitals According to the Impact of Future Heat Waves

NASA Astrophysics Data System (ADS)

Smid, M.; Costa, A. C.; Russo, S.; Pebesma, E. J.; Canut, C. G.

2017-12-01

In warming Europe, we are witnessing a growth in urban population with aging trend, which will make the society more vulnerable to extreme heat waves. In the period 1950-2015 the occurrence of extreme heat waves increased across European capitals. As an example, Moscow was hit by the strongest heat wave of the present era, killing more than ten thousand people. Here we focus on larger metropolitan areas of European capitals. By using observations and an ensemble of eight EURO-CORDEX models under the RCP8.5 scenario, we calculate a suite of temperature based climate indices. We introduce a simple ranking procedure based on ensemble predictions using the mean of metropolitan grid cells for each capital, and population density as a proxy to quantify the future impact. Results show that the selected ensemble provides solid simulation of climate characteristics over most of the targeted metropolitan areas. All the investigated European metropolitan areas will be more vulnerable to extreme heat in the coming decades. Based on the impact ranking, the results reveal that in near, but mainly in distant future, the extreme heat events in European capitals will be not exclusive to traditionally exposed areas such as the Mediterranean and the Iberian Peninsula. The ranking of European capitals based on their vulnerability to the extreme heat could be of paramount importance to the decision makers in order to mitigate the heat related mortality, especially with the foreseen increase of global mean temperature. Acknowledgments: The authors gratefully acknowledge the support of Geoinformatics: Enabling Open Cities (GEO-C), the project funded by the European Commission within the Marie Skłodowska-Curie Actions, International Training Networks (ITN), European Joint Doctorates (EJD). Grant Agreement number 642332 — GEO-C — H2020-MSCA-ITN-2014.

Throwing Icebergs at White Dwarfs

NASA Astrophysics Data System (ADS)

Kohler, Susanna

2017-08-01

Where do the metals come from that pollute the atmospheres of many white dwarfs? Close-in asteroids may not be the only culprits! A new study shows that distant planet-size and icy objects could share some of the blame.Pollution ProblemsArtists impression of rocky debris lying close around a white dwarf star. [NASA/ESA/STScI/G. Bacon]When a low- to intermediate-mass star reaches the end of its life, its outer layers are blown off, leaving behind its compact core. The strong gravity of this white dwarf causes elements heavier than hydrogen and helium to rapidly sink to its center in a process known as sedimentation, leaving an atmosphere that should be free of metallic elements.Therefore its perhaps surprising that roughly 2550% of all white dwarfs are observed to have atmospheric pollution by heavy elements. The short timescales for sedimentation suggest that these elements were added to the white dwarf recently but how did they get there?Bringing Ice InwardIn the generally accepted theory, pre-existing rocky bodies or an orbiting asteroid belt survive the stars evolution, later accreting onto the final white dwarf. But this scenario doesnt explain a few observations that suggest white dwarfs might be accreting larger planetary-size bodies and bodies with ices and volatile materials.Dynamical evolution of a Neptune-like planet (a) and a Kuiper belt analog object (b) in wide binary star systems. Both have large eccentricity excitations during the white dwarf phase. [Stephan et al. 2017]How might you get large or icy objects which would begin on very wide orbits close enough to a white dwarf to become disrupted and accrete? Led by Alexander Stephan, a team of scientists at UCLA now suggest that the key is for the white dwarf to be in a binary system.Influence of a CompanionIn the authors model, the white-dwarf progenitor is orbited by both a distant stellar companion (a common occurrence) and a number of large potential polluters, which could have masses between that of a large asteroid up to several times the mass of Jupiter. These potential polluters have very wide orbits that allow them to maintain ice and volatile materials.At the end of the progenitors lifetime it loses a significant amount of mass, causing the orbits of the surviving objects in the system to expand. After this stage, the stellar companion gravitationally perturbs the potential polluters onto extremely eccentric orbits, bringing these massive and long-period objects close enough accrete onto what is now the white dwarf.The Need for ObservationsThe likelihood distributions for orbital parameters of the systems that result in white dwarfs polluted by Neptune-like planets and Kuiper-belt-analog objects. The black arrows mark the parameters for one of the few observed systems, WD 1425+540, for comparison. [Stephan et al. 2017]By running large Monte Carlo simulations, Stephan and collaborators demonstrate that this scenario can successfully produce accretion of both Neptune-like planets and Kuiper-belt-analog objects. Their simulation results indicate that 1% of all white dwarfs should accrete Neptune-like planets, and 7.5% of all white dwarfs should accrete Kuiper-belt-analog objects.While these fractions are broadly consistent with observations, its hard to say with certainty whether this model is correct, as observations are scant. Only 200 polluted white dwarfs have been observed, and of these, only 15 have had detailed abundance measurements made. Next steps for understanding white-dwarf pollution certainly must includegathering more observations of polluted white dwarfs and establishing the statistics of what is polluting them.CitationAlexander P. Stephan et al 2017 ApJL 844 L16. doi:10.3847/2041-8213/aa7cf3

Neurodegenerative disease and magnetic field exposure in UK electricity supply workers.

PubMed

Sorahan, T; Mohammed, N

2014-09-01

Previous research has suggested a possible link between neurodegenerative disease and exposure to extremely low-frequency electric and magnetic fields. To investigate whether risks of Alzheimer's, motor neurone or Parkinson's disease are related to occupational exposure to magnetic fields. The mortality experienced by a cohort of 73051 employees of the former Central Electricity Generating Board of England and Wales was investigated for the period 1973-2010. All employees were hired in the period 1952-82, were employed for at least 6 months and had some employment after 1 January 1973. Detailed calculations had been performed by others to enable an assessment to be made of exposures to magnetic fields. Poisson regression was used to calculate relative risks (rate ratios) of developing any of the three diseases under investigation for categories of lifetime, distant (lagged) and recent (lugged) exposure. No statistically significant trends were shown for risks of any of these diseases to increase with estimates of lifetime, recent or distant exposure to magnetic fields. There is no convincing evidence that UK electricity generation and transmission workers have suffered elevated risks from neurodegenerative diseases as a consequence of exposure to magnetic fields. © The Author 2014. Published by Oxford University Press on behalf of the Society of Occupational Medicine. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Genetic structure of the crown-of-thorns seastar in the Pacific Ocean, with focus on Guam

PubMed Central

Tusso, Sergio; Morcinek, Kerstin; Vogler, Catherine; Schupp, Peter J.; Caballes, Ciemon F.; Vargas, Sergio

2016-01-01

Population outbreaks of the corallivorous crown-of-thorns seastar (COTS), Acanthaster ‘planci’ L., are among the most important biological disturbances of tropical coral reefs. Over the past 50 years, several devastating outbreaks have been documented around Guam, an island in the western Pacific Ocean. Previous analyses have shown that in the Pacific Ocean, COTS larval dispersal may be geographically restricted to certain regions. Here, we assess the genetic structure of Pacific COTS populations and compared samples from around Guam with a number of distant localities in the Pacific Ocean, and focused on determining the degree of genetic structure among populations previously considered to be isolated. Using microsatellites, we document substantial genetic structure between 14 localities from different geographical regions in the Pacific Ocean. Populations from the 14 locations sampled were found to be structured in three significantly differentiated groups: (1) all locations immediately around Guam, as well as Kingman Reef and Swains Island; (2) Japan, Philippines, GBR and Vanuatu; and (3) Johnston Atoll, which was significantly different from all other localities. The lack of genetic differentiation between Guam and extremely distant populations from Kingman Reef and Swains Island suggests potential long-distance dispersal of COTS in the Pacific. PMID:27168979

Galaxy Evolution Studies with the SPace IR Telescope for Cosmology and Astrophysics (SPICA): The Power of IR Spectroscopy

NASA Astrophysics Data System (ADS)

Spinoglio, L.; Alonso-Herrero, A.; Armus, L.; Baes, M.; Bernard-Salas, J.; Bianchi, S.; Bocchio, M.; Bolatto, A.; Bradford, C.; Braine, J.; Carrera, F. J.; Ciesla, L.; Clements, D. L.; Dannerbauer, H.; Doi, Y.; Efstathiou, A.; Egami, E.; Fernández-Ontiveros, J. A.; Ferrara, A.; Fischer, J.; Franceschini, A.; Gallerani, S.; Giard, M.; González-Alfonso, E.; Gruppioni, C.; Guillard, P.; Hatziminaoglou, E.; Imanishi, M.; Ishihara, D.; Isobe, N.; Kaneda, H.; Kawada, M.; Kohno, K.; Kwon, J.; Madden, S.; Malkan, M. A.; Marassi, S.; Matsuhara, H.; Matsuura, M.; Miniutti, G.; Nagamine, K.; Nagao, T.; Najarro, F.; Nakagawa, T.; Onaka, T.; Oyabu, S.; Pallottini, A.; Piro, L.; Pozzi, F.; Rodighiero, G.; Roelfsema, P.; Sakon, I.; Santini, P.; Schaerer, D.; Schneider, R.; Scott, D.; Serjeant, S.; Shibai, H.; Smith, J.-D. T.; Sobacchi, E.; Sturm, E.; Suzuki, T.; Vallini, L.; van der Tak, F.; Vignali, C.; Yamada, T.; Wada, T.; Wang, L.

2017-11-01

IR spectroscopy in the range 12-230 μm with the SPace IR telescope for Cosmology and Astrophysics (SPICA) will reveal the physical processes governing the formation and evolution of galaxies and black holes through cosmic time, bridging the gap between the James Webb Space Telescope and the upcoming Extremely Large Telescopes at shorter wavelengths and the Atacama Large Millimeter Array at longer wavelengths. The SPICA, with its 2.5-m telescope actively cooled to below 8 K, will obtain the first spectroscopic determination, in the mid-IR rest-frame, of both the star-formation rate and black hole accretion rate histories of galaxies, reaching lookback times of 12 Gyr, for large statistically significant samples. Densities, temperatures, radiation fields, and gas-phase metallicities will be measured in dust-obscured galaxies and active galactic nuclei, sampling a large range in mass and luminosity, from faint local dwarf galaxies to luminous quasars in the distant Universe. Active galactic nuclei and starburst feedback and feeding mechanisms in distant galaxies will be uncovered through detailed measurements of molecular and atomic line profiles. The SPICA's large-area deep spectrophotometric surveys will provide mid-IR spectra and continuum fluxes for unbiased samples of tens of thousands of galaxies, out to redshifts of z 6.

A close-pair binary in a distant triple supermassive black hole system.

PubMed

Deane, R P; Paragi, Z; Jarvis, M J; Coriat, M; Bernardi, G; Fender, R P; Frey, S; Heywood, I; Klöckner, H-R; Grainge, K; Rumsey, C

2014-07-03

Galaxies are believed to evolve through merging, which should lead to some hosting multiple supermassive black holes. There are four known triple black hole systems, with the closest black hole pair being 2.4 kiloparsecs apart (the third component in this system is at 3 kiloparsecs), which is far from the gravitational sphere of influence (about 100 parsecs for a black hole with mass one billion times that of the Sun). Previous searches for compact black hole systems concluded that they were rare, with the tightest binary system having a separation of 7 parsecs (ref. 10). Here we report observations of a triple black hole system at redshift z = 0.39, with the closest pair separated by about 140 parsecs and significantly more distant from Earth than any other known binary of comparable orbital separation. The effect of the tight pair is to introduce a rotationally symmetric helical modulation on the structure of the large-scale radio jets, which provides a useful way to search for other tight pairs without needing extremely high resolution observations. As we found this tight pair after searching only six galaxies, we conclude that tight pairs are more common than hitherto believed, which is an important observational constraint for low-frequency gravitational wave experiments.

Social Networks and Health Among Older Adults in Lebanon: The Mediating Role of Support and Trust

PubMed Central

Antonucci, Toni C.; Ajrouch, Kristine J.; Abdulrahim, Sawsan

2015-01-01

Objectives. Despite a growing body of literature documenting the influence of social networks on health, less is known in other parts of the world. The current study investigates this link by clustering characteristics of network members nominated by older adults in Lebanon. We then identify the degree to which various types of people exist within the networks. This study further examines how network composition as measured by the proportion of each type (i.e., type proportions) is related to health; and the mediating role of positive support and trust in this process. Method. Data are from the Family Ties and Aging Study (2009). Respondents aged ≥60 were selected (N = 195) for analysis. Results. Three types of people within the networks were identified: Geographically Distant Male Youth, Geographically Close/Emotionally Distant Family, and Close Family. Having more Geographically Distant Male Youth in one’s network was associated with health limitations, whereas more Close Family was associated with no health limitations. Positive support mediated the link between type proportions and health limitations, whereas trust mediated the link between type proportions and depressive symptoms. Discussion. Results document links between the social networks and health of older adults in Lebanon within the context of ongoing demographic transitions. PMID:25324295

Advanced Image Enhancement Method for Distant Vessels and Structures in Capsule Endoscopy

PubMed Central

Pedersen, Marius

2017-01-01

This paper proposes an advanced method for contrast enhancement of capsule endoscopic images, with the main objective to obtain sufficient information about the vessels and structures in more distant (or darker) parts of capsule endoscopic images. The proposed method (PM) combines two algorithms for the enhancement of darker and brighter areas of capsule endoscopic images, respectively. The half-unit weighted-bilinear algorithm (HWB) proposed in our previous work is used to enhance darker areas according to the darker map content of its HSV's component V. Enhancement of brighter areas is achieved thanks to the novel threshold weighted-bilinear algorithm (TWB) developed to avoid overexposure and enlargement of specular highlight spots while preserving the hue, in such areas. The TWB performs enhancement operations following a gradual increment of the brightness of the brighter map content of its HSV's component V. In other words, the TWB decreases its averaged weights as the intensity content of the component V increases. Extensive experimental demonstrations were conducted, and, based on evaluation of the reference and PM enhanced images, a gastroenterologist (Ø.H.) concluded that the PM enhanced images were the best ones based on the information about the vessels, contrast in the images, and the view or visibility of the structures in more distant parts of the capsule endoscopy images. PMID:29225668

Extragalactic Supergiants

NASA Astrophysics Data System (ADS)

Urbaneja, Miguel A.; Kudritzki, Rolf P.

2017-11-01

Blue supergiant stars of B and A spectral types are amongst the visually brightest non-transient astronomical objects. Their intrinsic brightness makes it possible to obtain high quality optical spectra of these objects in distant galaxies, enabling the study not only of these stars in different environments, but also to use them as tools to probe their host galaxies. Quantitative analysis of their optical spectra provide tight constraints on their evolution in a wide range of metallicities, as well as on the present-day chemical composition, extinction laws and distances to their host galaxies. We review in this contribution recent results in this field.

Tripartite counterfactual entanglement distribution.

PubMed

Chen, Yuanyuan; Gu, Xuemei; Jiang, Dong; Xie, Ling; Chen, Lijun

2015-08-10

We propose two counterfactual schemes for tripartite entanglement distribution without any physical particles travelling through the quantum channel. One scheme arranges three participators to connect with the absorption object by using switch. Using the "chained" quantum Zeno effect, three participators can accomplish the task of entanglement distribution with unique counterfactual interference probability. Another scheme uses Michelson-type interferometer to swap two entanglement pairs such that the photons of three participators are entangled. Moreover, the distance of entanglement distribution is doubled as two distant absorption objects are used. We also discuss the implementation issues to show that the proposed schemes can be realized with current technology.

There Are (super)Giants in the Sky: Searching for Misidentified Massive Stars in Algorithmically-Selected Quasar Catalogs

NASA Astrophysics Data System (ADS)

Dorn-Wallenstein, Trevor Z.; Levesque, Emily

2017-11-01

Thanks to incredible advances in instrumentation, surveys like the Sloan Digital Sky Survey have been able to find and catalog billions of objects, ranging from local M dwarfs to distant quasars. Machine learning algorithms have greatly aided in the effort to classify these objects; however, there are regimes where these algorithms fail, where interesting oddities may be found. We present here an X-ray bright quasar misidentified as a red supergiant/X-ray binary, and a subsequent search of the SDSS quasar catalog for X-ray bright stars misidentified as quasars.

Aerial Vehicle Surveys of other Planetary Atmospheres and Surfaces: Imaging, Remote-sensing, and Autonomy Technology Requirements

NASA Technical Reports Server (NTRS)

Young, Larry A.; Pisanich, Gregory; Ippolito, Corey; Alena, Rick

2005-01-01

The objective of this paper is to review the anticipated imaging and remote-sensing technology requirements for aerial vehicle survey missions to other planetary bodies in our Solar system that can support in-atmosphere flight. In the not too distant future such planetary aerial vehicle (a.k.a. aerial explorers) exploration missions will become feasible. Imaging and remote-sensing observations will be a key objective for these missions. Accordingly, it is imperative that optimal solutions in terms of imaging acquisition and real-time autonomous analysis of image data sets be developed for such vehicles.

The distant red galaxy neighbour population of 1

NASA Astrophysics Data System (ADS)

Bornancini, C.; García Lambas, D.

We study the Distant Red Galaxy (DRG, J-Ks > 2.3) neighbour population of Quasi Stellar Objects (QSOs) selected from the Sloan Digital Sky Survey (SDSS) in the redshift range 1 < z < 2. We perform a similar analysis for optically obscured AGNs (i.e. with a limiting magnitude I > 24) detected in the mid-infrared (24 microns) with the Spitzer Space Telescope and a mean redshift z~2.2 in the Flamingos Extragalactic Survey (FLAMEX). We present results on the cross-correlation function of DRGs around QSOs and optically faint mid-infrared sources. The corresponding correlation length obtained for the QSO sample targets is r_0=5.4+/-1.6 Mpc. For the optically obscured galaxy sample we find r_0=8.9+/-1.4 Mpc. These results indicate that optically faint obscured sources are located in denser environment of evolved red galaxies compare to QSOs.

Black holes are neither particle accelerators nor dark matter probes.

PubMed

McWilliams, Sean T

2013-01-04

It has been suggested that maximally spinning black holes can serve as particle accelerators, reaching arbitrarily high center-of-mass energies. Despite several objections regarding the practical achievability of such high energies, and demonstrations past and present that such large energies could never reach a distant observer, interest in this problem has remained substantial. We show that, unfortunately, a maximally spinning black hole can never serve as a probe of high energy collisions, even in principle and despite the correctness of the original diverging energy calculation. Black holes can indeed facilitate dark matter annihilation, but the most energetic photons can carry little more than the rest energy of the dark matter particles to a distant observer, and those photons are actually generated relatively far from the black hole where relativistic effects are negligible. Therefore, any strong gravitational potential could probe dark matter equally well, and an appeal to black holes for facilitating such collisions is unnecessary.

Toying with the moon illusion.

PubMed

Lockhead, G R; Wolbarsht, M L

1991-08-20

We propose that the correct interpretation of the moon illusion is that the zenith moon appears small, not that the horizon moon appears large. This illusion is caused by the visual gap between the observer and the overhead moon. Because of the gap, the observer has no or little optical information about the distance of the moon. This results in empty field myopia where the moon is neurally, although not necessarily cognitively, processed as being at about arm's length. When the moon is seen on the horizon, there usually is optical information about distance. That results in reduced accommodation, and so the moon is processed as at a greater distance. Consistent with the size-distance-invariance hypothesis, the moon is then judged as large. This is a specific example of the more general fact that all distant objects appear small in the absence of a stimulus for accommodation to be distant. This outcome produces the toy illusion.

A DISTANT QUASAR'S BRILLIANT LIGHT

NASA Technical Reports Server (NTRS)

2002-01-01

The arrow in this image, taken by a ground-based telescope, points to a distant quasar, the brilliant core of an active galaxy residing billions of light-years from Earth. As light from this faraway object travels across space, it picks up information on galaxies and the vast clouds of material between galaxies as it moves through them. The Space Telescope Imaging Spectrograph aboard NASA's Hubble Space Telescope decoded the quasar's light to find the spectral 'fingerprints' of highly ionized (energized) oxygen, which had mixed with invisible clouds of hydrogen in intergalactic space. The quasar's brilliant beam pierced at least four separate filaments of the invisible hydrogen laced with the telltale oxygen. The presence of oxygen between the galaxies implies there are huge quantities of hydrogen in the universe. Credits: WIYN Telescope at Kitt Peak National Observatory in Arizona. The telescope is owned and operated by the University of Wisconsin, Indiana University, Yale University, and the National Optical Astronomy Observatories.

UVES Investigates the Environment of a Very Remote Galaxy

NASA Astrophysics Data System (ADS)

2002-03-01

Surplus of Intergalactic Material May Be Young Supercluster Summary Observations with ESO's Very Large Telescope (VLT) have enabled an international group of astronomers [1] to study in unprecedented detail the surroundings of a very remote galaxy, almost 12 billion light-years distant [2]. The corresponding light travel time means that it is seen at a moment only about 3 billion years after the Big Bang. This galaxy is designated MS 1512-cB58 and is the brightest known at such a large distance and such an early time. This is due to a lucky circumstance: a massive cluster of galaxies ( MS 1512+36 ) is located about halfway along the line-of-sight, at a distance of about 7 billion light-years, and acts as a gravitational "magnifying glass". Thanks to this lensing effect, the image of MS1512-cB58 appears 50 times brighter . Nevertheless, the apparent brightness is still as faint as magnitude 20.6 (i.e., nearly 1 million times fainter than what can be perceived with the unaided eye). Moreover, MS 1512-cB58 is located 36° north of the celestial equator and never rises more than 29° above the horizon at Paranal. It was therefore a great challenge to secure the present observational data with the UVES high-dispersion spectrograph on the 8.2-m VLT KUEYEN telescope . The extremely detailed UVES-spectrum of MS 1512-cB58 displays numerous signatures (absorption lines) of intergalactic gas clouds along the line-of-sight . Some of the clouds are quite close to the galaxy and the astronomers have therefore been able to investigate the distribution of matter in its immediate surroundings. They found an excess of material near MS 1512-cB58, possible evidence of a young supercluster of galaxies , already at this very early epoch. The new observations thus provide an invaluable contribution to current studies of the birth and evolution of structures in the early Universe. This is the first time this kind of observation has ever been done of a galaxy at such a large distance . All previous studies were based on much more luminous quasars (QSOs - extremely active galaxy nuclei). However, any investigation of the intergalactic matter around a quasar is complicated by the strong radiation and consequently, high ionization of the gas by the QSO itself, rendering an unbiased assessment of the gas distribution impossible. PR Photo 08a/02 : HST photo of MS 1512-cB58 . PR Photo 08b/02 : UVES spectrum of MS 1512-cB58. PR Photo 08c/02 : UVES spectrum of MS 1512-cB58 ( detail ). Clustering in the Early Universe ESO PR Photo 08a/02 ESO PR Photo 08a/02 [Preview - JPEG: 400 x 614 pix - 304k] [Normal - JPEG: 1200 x 1843 pix - 1.8M] Caption : PR Photo 08a/02 shows the gravitationally amplified, elongated image of the very distant, 20.6-mag galaxy MS 1512-cB58 (indicated with an arrow), as seen in the field of the distant cluster of galaxies MS 1512+36 . The photo is based on exposures with the NASA/ESA Hubble Space Telescope (HST). Technical information about the photo is available below. With new and powerful astronomical telescopes, the exploration of the young Universe is progressing rapidly . By means of highly efficient instruments, scientists are now probing the objects seen at these early times in ever greater detail, painstakingly gaining precious new knowledge about these crucial evolutionary stages. They form an integral part of the long chain of events that has ultimately led to our own existence - no wonder that we would like to know more about those remote times! One of the key questions now asked by cosmologists is how the matter in the early Universe assembled into larger structures . With plenty of gaseous material available, it appears that contraction set in rather soon after the Big Bang, perhaps only a few hundred million years after this initial explosion. Stars and proto-galaxies formed, a web-like structure emerged (cf. ESO PR 11/01 ) and at some moment, these larger building blocks began to gather into "clusters" and "clusters of clusters" (superclusters) . This process took time and it is not yet known when the first major clusters of galaxies formed. However, recent results from the ESO Very Large Telescope at Paranal are casting new light on those early events and may actually provide evidence of an extensive cluster of clouds, perhaps a real supercluster , as early as only 3 billion years after the Big Bang. The lighthouse and the forest In order to investigate the large-scale structure of the Universe, astronomers have since some time employed the powerful technique of spectral analysis of the light from remote "lighthouses" (or "beacons") . One of the strongest spectral lines seen in astronomical objects is the Lyman-alpha line of atomic hydrogen . It is normally seen as a bright spectral peak (an "emission line") in the "lighthouse" object. The rest wavelength is 121.6 nm in the far-ultraviolet part of the spectrum. That spectral region is not accessible to ground-based telescopes - UV-light does not pass through the Earth's atmosphere. However, in very distant objects, the Lyman-alpha line is redshifted towards longer wavelengths and becomes observable from the ground [2]. On its way to us, the light beam from a bright and distant object traverses a long path , mostly through (nearly) empty space. However, once in a while, it passes through a cloud of matter, for instance in the outskirts of a remote galaxy. Each time, specific signatures from the atoms and molecules in that cloud are imprinted on the passing light in the form of spectral absorption lines at particular wavelengths. Such clouds contain hydrogen and thus produce a specific Lyman-alpha signature in the spectrum of the "lighthouse" object [3] Because of the different distances of the individual clouds, their Lyman-alpha spectral lines have different "redshifts" and are therefore observed at different wavelengths. In practice, the Lyman-alpha absorption lines from the intervening clouds are located on the blueward side (i.e., at shorter wavelengths because of their smaller redshifts) of the main emission peak, giving rise to the concept of a "Lyman-alpha forest" of spectral absorption lines. In some cases, over one thousand absorption lines have been seen, showing the presence of as many individual hydrogen-rich gas clouds along the line-of-sight towards the background "lighthouse", cf. ESO PR 15/99 and ESO PR 08/00. MS 1512-cB58 : a bright and remote galaxy MS 1512-cB58 is a remote, very bright galaxy, located at a distance of approximately 12 billion light-years in the northern constellation of Boötes. Its light has travelled 12 billion years to reach us and we therefore observe it as it was when the Universe was about 3 billion years old. Because of the extremely large distance, this galaxy would normally only be seen as a very faint object in the sky, so faint indeed that it could not be observed in any detail by existing telescopes. However, we are lucky, thanks to the fortuitious effect of gravitational lensing . About halfway on its way to us, the light from MS 1512-cB58 happens to pass through the strong gravitational field of a cluster of galaxies known as MS 1512+36 and this produces an amazingly efficient focussing effect: the light from MS 1512-cB58 that finally reaches us has been amplified no less than some 50 times! This beneficial effect makes all the difference. At the observed magnitude of 20.6 - though still nearly 1 million times fainter than what can be perceived with the unaided eye - MS 1512-cB58 is the best suited remote object of its type for the above mentioned kind of investigation. Thus, a detailed study of its spectrum, in particular the spectral region on the shortward side of the Lyman-alpha line (seen in absorption in this comparatively "normal" galaxy), provides very useful information about the many clouds of hydrogen that are located along the line-of-sight towards this object. The UVES spectrum ESO PR Photo 08b/02 ESO PR Photo 08b/02 [Preview - JPEG: 512 x 400 pix - 184k] [Normal - JPEG: 1023 x 800 pix - 448k] ESO PR Photo 08c/02 ESO PR Photo 08c/02 [Preview - JPEG: 750 x 400 pix - 136k] [Normal - JPEG: 1500 x 800 pix - 288k] Caption : PR Photo 08b/02 shows a section of the UVES spectrum of the very distant, 20.6-mag galaxy MS 1512-cB58 , obtained with the UVES high-dispersion spectrograph at the VLT KUEYEN telescope. The Lyman-alpha absorption line from the galaxy itself is seen as the broad depression at about 4530 Å (453 nm; lower panel). The absorption lines at shorter wavelengths are the signatures of individual intergalactic clouds along the line-of-sight; they are indicated by red vertical lines. Blue arrows point at absorption lines associated with heavy elements present in the gas inside the MS 1512-cB58 galaxy. PR Photo 08c/02 is an enlargement of a small wavelength region that shows the full resolution and extreme wealth of information contained in the spectrum of this faint object. Also here, Lyman-alpha absorption lines arising in intervening intergalactic clouds are indicated by red vertical lines. Technical information about the photos is available below. Using one of the most efficient astronomical spectrographs available, the Ultraviolet-Visual Echelle Spectrograph (UVES) at the ESO Very Large Telescope (VLT) at the Paranal Observatory , an international group of astronomers [1] succeeded in obtaining a very detailed (high-dispersion) spectrum of MS 1512-cB58 . Despite the fact that this object is located some 36° north of the celestial equator and can therefore only be observed for about 90 min each night from Paranal (at geographical latitude 25° south), the superposition of several exposures obtained between March and August 2000 has produced the most detailed and informative spectrum ever obtained of a distant galaxy, cf. PR Photos 08b-c/02 . At the same time, it provides a very comprehensive map of the Universe to such a large distance along a line-of-sight , as this can be read from the numerous Lyman-alpha absorption lines from intervening clouds, seen in this spectrum. The surroundings of MS 1512-cB58 The astronomers were particularly interested in the distribution of clouds in the region of space near MS 1512-cB58 . Thanks to the excellent quality of the UVES data, it was possible to identify and measure a substantial number of Lyman-alpha lines blueward of the broad Lyman-alpha absorption line from the galaxy itself, present in the lower panel of PR Photo 08b/01 . They correspond to intergalactic hydrogen clouds comparatively near the "lighthouse" object MS 1512-cB58 . Most interestingly, it turned out that there are exceptionally many such clouds rather near this remote galaxy (the corresponding absorption lines are seen in the middle panel of PR Photo 08b/01 of which a small part has been enlarged for clarity in PR Photo 08c/01 . Comparing with the mean density along the line-of-sight, a surplus of about 200% was evident. An effect of this dimension has never been seen before near such a remote object, i.e., at such an early epoch, only 3 billion years after the Big Bang. A young supercluster? What does this tell us? The astronomers have two explanations: either we are seeing a very large cluster of clouds (proto-galaxies) at some distance from MS 1512-cB58 , or the clouds are in some way directly connected to the environment of that galaxy. A rich distribution of gas clouds is indeed expected around star-forming galaxies like MS 1512-cB58 at this early epoch. For various reasons, however, including the actual distribution of the observed clouds, the astronomers do not favour the second hypothesis. It appears more likely that these clouds are separate objects not related to MS 1512-cB58 . In that case, this would imply the presence of large-scale structure at this early time , only 3 billion years after the Big Bang. MS 1512-cB58 might then be the largest (heaviest) single object in the neigbourhood, a likely progenitor of the local massive galaxies observed at the present time. More information The results described in this Press Release are presented in a research paper "The Lyman-alpha forest of a Lyman-Break Galaxy: VLT Spectra of MS 1512-cB58 at z = 2.724" by Sandra Savaglio, Nino Panagia and Paolo Padovani, appearing in the research journal "Astrophysical Journal" this month. Notes [1]: The team consists of Sandra Savaglio (Johns Hopkins University, Baltimore, MD, USA, and Rome Observatory, Italy), Nino Panagia and Paolo Padovani (both European Space Agency and Space Telescope Science Institute, Baltimore) [2]: The measured redshift of MS 1512-cB58 is z = 2.724. In astronomy, the redshift denotes the fraction by which the lines in the spectrum of an object are shifted towards longer wavelengths. The observed redshift of a distant cloud or galaxy gives a direct estimate of the apparent recession velocity as caused by the universal expansion. Since the expansion rate increases with distance, the velocity is itself a function (the Hubble relation) of the distance to the object. The distances indicated in the text are based on an age of the Universe of 15 billion years. At the indicated redshift, the Lyman-alpha line of atomic hydrogen (rest wavelength 121.6 nm) is observed at 452.8 nm, i.e. in the blue spectral region. The Lyman-alpha absorption lines from intergalactic clouds along the line-of-sight (and at lower redshifts) are observed at shorter wavelengths. The lower limit of the UVES spectrum of MS 1512-cB58 (415 nm) corresponds to a Lyman-alpha redshift of 2.41, i.e. a distance of about 7.5 billion light-years. [3]: The importance of the Lyman-alpha line in absorption is that it is exquisitely sensitive to the presence of neutral hydrogen which only constitutes a small fraction of the total amount of hydrogen in the intergalactic medium (about 1/10,000). Still, the observed Ly-alpha forest is extremely rich. What we see is most likely the "tip of the iceberg" only and hydrogen in the intergalactic medium at high redshift is probably the dominant component of baryonic matter in the early Universe. Contact Sandra Savaglio Johns Hopkins University Baltimore, MD, USA Tel.: +1 410 516 8583 email: savaglio@pha.jhu.edu Technical information about the photos PR Photo 08a/02 is a reproduction of a composite image of the field around the distant cluster of galaxies MS 1512+36 (redshift 0.37), obtained with the WFPC2 camera at the NASA/ESA Hubble Space Telescope. It is based on exposures in two filters (F555 + F675). The observations are described in a research paper by Seitz et al. (Monthly Notices of the RAS, August 1998, Vol. 298, p. 945 ff). The lensed image of the galaxy MS 1512-cB58 is seen at an angular distance of about 5 arcsec from the centre of the cluster. The north direction is at about 1 o'clock and east is at 10 o'clock. The field measures approx. 45 x 60 arcsec 2. PR Photo 08b/02 shows the composite spectrum of MS 1512-cB58 in the spectral region of interest (415.0 - 459.5 nm), as obtained with the red and blue arms of UVES. Long and short red vertical lines ("ticks") indicate larger and smaller intergalactic hydrogen clouds, respectively. The overlying, continuous red line is the "best-fit" model to the observed spectrum. Due to the low altitude of the object, the exposures never lasted more than 90 min around the northern meridian. The full spectral coverage is 415 - 500 nm (blue arm) and 524 - 621 nm (red arm). The velocity resolution varies from 29 km/s at the blue end to 19 km/sec at the red limit. The S/N-ratio increases from about 3 (415 nm) to 10 (610 nm). PR Photo 08c/02 reproduces a smaller part of the observed spectral region observed at full resolution (434.8 - 443.0 nm), with two dozen detected clouds indicated.

Disparities in the Presentation and Management of Cutaneous Melanoma That Required Admission.

PubMed

Al-Qurayshi, Zaid; Srivastav, Sudesh; Wang, Alun; Boh, Erin; Hamner, John; Hassan, Mohamed; Kandil, Emad

2018-06-18

In this study, we aimed to examine the association of demographic and socioeconomic factors with cutaneous melanoma that required admission. A cross-sectional study utilizing the Nationwide Inpatient Sample database, 2003-2009, was merged with County Health Rankings Data. A total of 2,765 discharge -records were included. Men were more likely to have melanoma in the head, neck, and trunk regions (p < 0.001), while extremities melanoma was more common in women (p < 0.001). Males had a higher risk of lymph node metastasis on presentation (OR 1.54, 95% CI [1.27-1.89]). Blacks and Hispanics were more likely to present with extremities melanoma. Patients with low annual income were more likely to be treated by low-volume surgeons and in hospitals located in high-risk communities (p < 0.05 each). Patients with Medicaid coverage were twice as likely to present with distant metastasis and were more likely to be managed by low-volume surgeons (p < 0.05 each). The presentation and outcomes of cutaneous melanoma have a distinct pattern of distribution based on patients' characteristics. © 2018 S. Karger AG, Basel.

Acute septic arthritis of the temporomandibular joint derived from otitis media: a report and review of the English and Japanese literature.

PubMed

Ishikawa, Shigeo; Watanabe, Tomoo; Iino, Mitsuyoshi

2017-03-01

Septic arthritis of the temporomandibular joint (SATMJ) is an extremely rare disease with characteristic features of preauricular pain, swelling, redness, and malocclusion. The present report describes a case of SATMJ derived from otitis media, which resulted in a good outcome. We also reviewed the English and Japanese literature with special interest in etiology. It is generally agreed that contiguous or distant infection and trauma are common etiological factors of SATMJ. So far, these etiological factors are mainly discussed based on hypotheses rather than sufficient evidence. Therefore, in many past cases, accurate causes were not identified. To our knowledge, our case is the third report of SATMJ following otitis media. In addition, this is the first case in which the pathogenic bacterium responsible for the otitis media was the definite cause of the SATMJ. Cases of SATMJ are sometimes misdiagnosed with otitis media, and SATMJ derived from otitis media is extremely rare. Dentists and otolaryngologists should collaborate for the management of this disease as needed.

Radio constraints on the nature of BL Lacertae objects and their parent population

NASA Technical Reports Server (NTRS)

Kollgaard, R. I.; Wardle, J. F. C.; Roberts, D. H.; Gabuzda, D. C.

1992-01-01

5 GHz VLA observations of 17 BL Lac objects with bright radio cores at both high and low resolution are reported. Extended emission is detected around most objects. None of the sources observed at low resolution show evidence of giant halos on the scale of tens of arcmin. In general, the sources with the most luminous extended emission exhibit FR II characteristics in both morphology and polarization, and less luminous sources exhibit FR I characteristics. Thus, the parent population of the BL Lac objects contains both FR I and FR II radio sources. No BL Lac objects are found that clearly exhibit quasarlike polarization at milliarcsec resolution. This argues against the view that the more luminous BL Lac objects are simply an extension of the quasar/OVV population, or that most BL Lac objects are gravitationally microlensed images of distant quasars. Other properties are generally consistent with the view the BL Lac objects are normal radio galaxies whose jets make a small angle to the line of sight.

Beyond MACS: A Snapshot Survey of the Most Massive Clusters of Galaxies at z>0.5

NASA Astrophysics Data System (ADS)

Ebeling, Harald

2017-08-01

Truly massive galaxy clusters play a pivotal role for a wealth of extragalactic and cosmological research topics, and SNAPshot observations of these systems are ideally suited to identify the most promising cluster targets for further, in-depth study. The power of this approach was demonstrated by ACS/WFC3 SNAPshots of X-ray selected MACS and eMACS clusters at z>0.3 obtained by us in previous Cycles (44 of them in all of F606W, F814W, F110W, and F140W). Based on these data, the CLASH MCT program selected 16 out of 25 of their targets to be MACS clusters. Similarly, all but one of the six most powerful cluster lenses selected for in-depth study by the HST Frontier Fields initiative are MACS detections, and so are 16 of the 29 z>0.3 clusters targeted by the RELICS legacy program.We propose to extend our spectacularly successful SNAPshot survey of the most X-ray luminous distant clusters to a redshift-mass regime that is poorly sampled by any other project. Targeting only extremely massive clusters at z>0.5 from the X-ray selected eMACS sample (median velocity dispersion: 1180 km/s), the proposed program will (a) identify the most powerful gravitational telescopes at yet higher redshift for the next generation of in-depth studies of the distant Universe with HST and JWST, (b) provide constraints on the mass distribution within these extreme systems, (c) help improve our understanding of the physical nature of galaxy-galaxy and galaxy-gas interactions in cluster cores, and (d) unveil Balmer Break Galaxies at z 2 and Lyman-break galaxies at z>6 as F814W dropouts.Acknowledging the broad community interest in our sample we waive our data rights for these observations.

External-beam radiation therapy combined with limb-sparing surgery in elderly patients (>70 years) with primary soft tissue sarcomas of the extremities : A retrospective analysis.

PubMed

Andrä, Claudia; Klein, Alexander; Dürr, Hans Roland; Rauch, Josefine; Lindner, Lars Hartwin; Knoesel, Thomas; Angele, Martin; Baur-Melnyk, Andrea; Belka, Claus; Roeder, Falk

2017-08-01

To report our experience with EBRT combined with limb-sparing surgery in elderly patients (>70 years) with primary extremity soft tissue sarcomas (STS). Retrospectively analyzed were 35 patients (m:f 18:17, median 78 years) who all presented in primary situation without nodal/distant metastases (Charlson score 0/1 in 18 patients; ≥2 in 17 patients). Median tumor size was 10 cm, mainly located in lower limb (83%). Stage at presentation (UICC7th) was Ib:3%, 2a:20%, 2b:20%, and 3:57%. Most lesions were high grade (97%), predominantly leiomyosarcoma (26%) and undifferentiated pleomorphic/malignant fibrous histiocytoma (23%). Limb-sparing surgery was preceded (median 50 Gy) or followed (median 66 Gy) by EBRT. Median follow-up was 37 months (range 1-128 months). Margins were free in 26 patients (74%) and microscopically positive in 9 (26%). Actuarial 3‑ and 5‑year local control rates were 88 and 81% (4 local recurrences). Corresponding rates for distant control, disease-specific survival, and overall survival were 57/52%, 76/60%, and 72/41%. The 30-day mortality was 0%. Severe postoperative complications were scored in 8 patients (23%). Severe acute radiation-related toxicity was observed in 2 patients (6%). Patients with Charlson score ≥2 had a significantly increased risk for severe postoperative complications and acute radiation-related side effects. Severe late toxicities were found in 7 patients (20%), including fractures in 3 (8.6%). Final limb preservation rate was 97%. Combination of EBRT and limb-sparing surgery is feasible in elderly patients with acceptable toxicities and encouraging but slightly inferior outcome compared to younger patients. Comorbidity correlated with postoperative complications and acute toxicities. Late fracture risk seems slightly increased.

Clinical outcome of dedifferentiated liposarcoma in the extremities: A retrospective case series of 7 patients.

PubMed

Kito, Munehisa; Yoshimura, Yasuo; Isobe, Ken'ichi; Aoki, Kaoru; Suzuki, Shuichiro; Tanaka, Atsushi; Okamoto, Masanori; Sano, Kenji; Kato, Hiroyuki

2016-09-01

Wide resection is the generally recommended surgical treatment for dedifferentiated liposarcoma (DDLPS) in the extremities. However, it may be appropriate to distinguish the surgical margin of low-grade atypical lipomatous tumor (ALT)/well-differentiated liposarcoma (WDLPS) area from the high-grade dedifferentiated area, because the low- and high-grade areas can be clearly separated, both radiologically and histologically. This study re-evaluated the details of surgical margin of DDLPS in the extremities, and aimed to investigate the optimal surgical margin and the usefulness of adjuvant therapy for DDLPS in the extremities. Seven patients diagnosed with DDLPS in the extremities and treated between 1995 and 2013 were analyzed. The use of adjuvant therapy before and after surgery was assessed, and the surgical margins for the ALT/WDLPS and dedifferentiated areas were re-evaluated by using the specimens resected at surgery. Subsequently, the recurrence rates, metastatic rates, and oncological outcomes were examined. Four and three patients had wide (adequate wide margin, n = 3; inadequate wide margin, n = 1) and marginal margins for the dedifferentiated area, respectively, while three and four patients had wide (adequate wide margin, n = 2; inadequate wide margin, n = 1) and marginal margins for the ALT/WDLPS area, respectively. Postoperative radiotherapy was performed in three patients with an inadequate wide margin or a marginal margin for the dedifferentiated area. No patient had local recurrence. Distant metastases occurred in two patients. These patients died of their disease. The other five patients were disease-free. The ALT/WDLPS and dedifferentiated areas in the tumor margin may be better to be considered separately in determining the appropriate resection extent for DDLPS in the extremities. Postoperative radiotherapy may provide good local control for cases with a narrow surgical margin. Copyright © 2016 The Japanese Orthopaedic Association. Published by Elsevier B.V. All rights reserved.

Flickering Quasar Helps Chandra Measure the Expansion Rate of the universe

NASA Astrophysics Data System (ADS)

2000-11-01

Astronomers using the Chandra X-ray Observatory have identified a flickering, four-way mirage image of a distant quasar. A carefully planned observation of this mirage may be used to determine the expansion rate of the universe as well as to measure the distances to extragalactic objects, arguably two of the most important pursuits in modern astronomy. quasar RX J0911.4+0551 This figure is a composite of the X-ray image of the gravitational lens RX J0911.4+551 (top panel) and the light curves of the lensed images A2 (left panel) and A1 (right panel). Credit: NASA George Chartas, senior research associate at The Pennsylvania State University (Penn State) and Marshall W. Bautz, principal research scientist at the Massachusetts Institute of Technology (MIT) Center for Space Research, present their findings today at the meeting of the High Energy Astrophysics Division of the American Astronomical Society in Honolulu, Hawaii. "With a carefully planned follow-up, the Chandra observation of quasar RX J0911.4+0551 may lead to a measurement of the Hubble constant, the expansion rate of the universe, in less than a day," said Chartas. The observation would be done not with mirrors but with mirages--four images of a single quasar that capture the quasar's light at different moments of time due to the speed of light and the location of the mirages. Quasars are extremely distant galaxies with cores that glow with the intensity of 10 trillion Suns, a phenomenon likely powered by a supermassive black hole in the heart of the galaxy. This single "point source" image of a quasar may appear as four or five sources when the quasar--from our vantage point on Earth--is behind a massive intervening deflector, such as a dim galaxy. A mirage of images form when the gravity of the intervening deflector forces light rays to bend and take different paths to reach us. The time it takes for light to reach us from the distant object will depend on which path a ray decides to take. "An intervening galaxy can act as a lens," said Bautz. "Now imagine that the distant lensed quasar suddenly became brighter. The mirage images of the quasar will brighten up at different times depending on the difference in the light travel delay." Unlike ordinary galaxies, quasars do vary greatly in their intensity, especially in the X-ray waveband, said Gordon Garmire, Evan Pugh Professor of Astronomy and Astrophysics at Penn State. This is caused by the violent and erratic flow of gas into the black hole that is powering the quasar. In quasar RX J0911.4+0551, the astronomers saw a sudden brightening of X-ray intensity that lasted for about 2,000 seconds. This was observed in one of the four mirage images. Measuring the time-delay of the 2,000-second flare--or any flare-- from mirage to mirage can provide the absolute distance to the deflector (intervening galaxy) and can thus be used to estimate the expansion rate of the universe. Sjur Refsdal first proposed this promising method in 1964. The method avoids many uncertainties associated with the classic distance-ladder technique used to measure objects and the Hubble constant. The main difficulty in measuring time-delays is that the brightness of each image has to be carefully monitored over several periods of the time-delay. Also, the quasar has to show sufficient variability over time scales smaller than the time-delay. Most attempts to measure time-delays until now have been made in the optical and radio bands. The modest variability of quasars in these wavebands, however, has made it extremely difficult to place accurate constraints on time-delays. X-ray observations of gravitationally lensed quasars, on the other hand, show strong variability over time scales of hours to days. For example, it has taken almost 20 years of optical and radio monitoring to obtain a universal accepted time-delay for the lensed quasar Q0957+561 to an accuracy of 3percent. Chandra has the potential, the team has found, to determine the time-delay in one observation. "Based on computer models developed at Penn State and MIT, we have identified about ten gravitational lens systems with time-delays of less than a day," said Chartas. "One long observation of each source with a superior X-ray telescope could provide enough data to nail down the Hubble constant in the blink of an eye." The team is planning to apply the gravitational-lens method in the near future to several of these systems using the Chandra and XMM-Newton X-ray observatories. The Chandra observations of quasar RX J0911.4+0551 were made on November 2, 1999, using the Advanced CCD Imaging Spectrometer (ACIS). The effort involved several scientists from Penn State and MIT. ACIS was conceived and developed for NASA by Penn State and MIT under Garmire's leadership. NASA's Marshall Space Flight Center in Huntsville, Alabama, manages the Chandra program. TRW, Inc., in Redondo Beach, California, is the prime contractor for the spacecraft. The Smithsonian's Chandra X-ray Center controls science and flight operations from Cambridge, Massachusetts. RX J0911.4+551 Handout Constellation Hydra To follow Chandra's progress, visit the Chandra site at: http://chandra.harvard.edu AND http://chandra.nasa.gov

Management of Mediastinal Relapse after Treatment with Stereotactic Body Radiotherapy or Accelerated Hypofractionated Radiotherapy for Stage I/II Non–Small-Cell Lung Cancer

PubMed Central

Kilburn, Jeremy M.; Lester, Scott C.; Lucas, John T.; Soike, Michael H.; Blackstock, A. William; Kearns, William T.; Hinson, William H.; Miller, Antonius A.; Petty, William J.; Munley, Michael T.; Urbanic, James J.

2014-01-01

Purpose/Objective(s) Regional failures occur in up to 15% of patients treated with stereotactic body radiotherapy (SBRT) for stage I/II lung cancer. This report focuses on the management of the unique scenario of isolated regional failures. Methods Patients treated initially with SBRT or accelerated hypo-fractionated radiotherapy were screened for curative intent treatment of isolated mediastinal failures (IMFs). Local control, regional control, progression-free survival, and distant control were estimated from the date of salvage treatment using the Kaplan–Meier method. Results Among 160 patients treated from 2002 to 2012, 12 suffered IMF and were amenable to salvage treatment. The median interval between treatments was 16 months (2–57 mo). Median salvage dose was 66 Gy (60–70 Gy). With a median follow-up of 10 months, the median overall survival was 15 months (95% confidence interval, 5.8–37 mo). When estimated from original treatment, the median overall survival was 38 months (95% confidence interval, 17–71 mo). No subsequent regional failures occurred. Distant failure was the predominant mode of relapse following salvage for IMF with a 2-year distant control rate of 38%. At the time of this analysis, three patients have died without recurrence while four are alive and no evidence of disease. High-grade toxicity was uncommon. Conclusions To our knowledge, this is first analysis of salvage mediastinal radiation after SBRT or accelerated hypofractionated radiotherapy in lung cancer. Outcomes appear similar to stage III disease at presentation. Distant failures were common, suggesting a role for concurrent or sequential chemotherapy. A standard full course of external beam radiotherapy is advisable in this unique clinical scenario. PMID:24736084

Selections from 2017: Hubble Survey Explores Distant Galaxies

NASA Astrophysics Data System (ADS)

Kohler, Susanna

2017-12-01

Editors note:In these last two weeks of 2017, well be looking at a few selections that we havent yet discussed on AAS Nova from among the most-downloaded paperspublished in AAS journals this year. The usual posting schedule will resume in January.CANDELS Multi-Wavelength Catalogs: Source Identification and Photometry in the CANDELS COSMOSSurvey FieldPublished January2017Main takeaway:A publication led byHooshang Nayyeri(UC Irvine and UC Riverside) early this year details acatalog of sources built using the Cosmic Assembly Near-infrared Deep Extragalactic Legacy Survey(CANDELS), a survey carried out by cameras on board the Hubble Space Telescope. The catalogliststhe properties of 38,000 distant galaxies visiblewithin the COSMOS field, a two-square-degree equatorial field explored in depthto answer cosmological questions.Why its interesting:Illustration showing the three-dimensional map of the dark matter distribution in theCOSMOS field. [Adapted from NASA/ESA/R. Massey(California Institute of Technology)]The depth and resolution of the CANDELS observations areuseful for addressingseveral major science goals, including the following:Studying the most distant objects in the universe at the epoch of reionization in the cosmic dawn.Understanding galaxy formation and evolution during the peak epoch of star formation in the cosmic high noon.Studying star formation from deep ultravioletobservations and studying cosmology from supernova observations.Why CANDELS is a major endeavor:CANDELS isthe largest multi-cycle treasury program ever approved on the Hubble Space Telescope using over 900 orbits between 2010 and 2013 withtwo cameras on board the spacecraftto study galaxy formation and evolution throughout cosmic time. The CANDELS images are all publicly available, and the new catalogrepresents an enormous source of information about distant objectsin our universe.CitationH. Nayyeri et al 2017 ApJS 228 7. doi:10.3847/1538-4365/228/1/7

Signatures Of A Putative Planetary Mass Solar Companion On The Orbital Distribution Of Tno's And Centaurs

NASA Astrophysics Data System (ADS)

Gomes, Rodney S.; Soares, J. S.

2012-05-01

Gomes et al. 2006 (Icarus 184, 589) show that a planetary mass solar companion (PMSC) can produce orbits in an inner Oort cloud that can account for Sedna's orbit. On the other hand, one should expect that this faraway planet would also produce some peculiar orbital distribution for distant TNO's and Centaurs. A pair of interesting orbits in this respect are those of 2006 SQ372 and 2000 OO67. These objects have very large semimajor axes and perihelion between Uranus and Neptune orbits. It has been claimed that a likely source for 2006 SQ372 is the Oort cloud. Yet a PMSC has an important effect on objects at inner Oort cloud distances, say between 300 AU and 2000 AU, to make their perihelion distances to continually oscillate with a large enough amplitude to account for objects both inside and outside Neptune's orbit. This naturally produces an extra amount of TNO's with semimajor axes between 300 and 2000 AU and perihelion inside Neptune's orbit, like 2006 SQ372 and 2000 OO67. This signature should be found in present observations. To deal with this problem we construct a numerical simulator and apply it to populations of distant TNO's produced by numerical integration of planetesimals and planets according to the Nice model, either including or not a PMSC. With the results from the numerical simulator we compare the model with and without the PMSC with observations. We conclude that a PMSC is compatible with the existence of 2006 SQ372 and 2000 OO67 and, in fact, although not conclusively, we can also claim that the observations of 2006 SQ372 and 2000 OO67, compared to all other scattered objects, would be lucky events if no PMSC exists.

Mission objectives for geological exploration of the Apollo 16 landing site

NASA Technical Reports Server (NTRS)

Muehlberger, W. R.; Horz, F.; Sevier, J. R.; Ulrich, G. E.

1980-01-01

The objectives of the Apollo 16 mission to delineate the nature and origin of two major physiographic units of the central lunar highlands are discussed. Surface exploration plans, specific sampling procedures, operational constraints, and suites of samples that were collected for specific local objectives are described. Pre-mission hypotheses that favored a volcanic origin for the Cayley plains as well as the Descartes mountains were proved to be wrong by the mission results, but not enough samples have been studied to draw any other definite conclusions. Two contrasting schools of thought about the origin of the Apollo fragmental impact deposits are described: one maintains that the samples are predominantly of local origin, while the other suggests more distant, basin-related sources.

Pedestrian evacuation modeling to reduce vehicle use for distant tsunami evacuations in Hawaiʻi

USGS Publications Warehouse

Wood, Nathan J.; Jones, Jamie; Peters, Jeff; Richards, Kevin

2018-01-01

Tsunami waves that arrive hours after generation elsewhere pose logistical challenges to emergency managers due to the perceived abundance of time and inclination of evacuees to use vehicles. We use coastal communities on the island of Oʻahu (Hawaiʻi, USA) to demonstrate regional evacuation modeling that can identify where successful pedestrian-based evacuations are plausible and where vehicle use could be discouraged. The island of Oʻahu has two tsunami-evacuation zones (standard and extreme), which provides the opportunity to examine if recommended travel modes vary based on zone. Geospatial path distance models are applied to estimate population exposure as a function of pedestrian travel time and speed out of evacuation zones. The use of the extreme zone triples the number of residents, employees, and facilities serving at-risk populations that would be encouraged to evacuate and slightly reduces the percentage of residents (98–76%) that could evacuate in less than 15 min at a plausible speed (with similar percentages for employees). Areas with lengthy evacuations are concentrated in the North Shore region for the standard zone but found all around the Oʻahu coastline for the extreme zone. The use of the extreme zone results in a 26% increase in the number of hotel visitors that would be encouraged to evacuate, and a 76% increase in the number of them that may require more than 15 min. Modeling can identify where pedestrian evacuations are plausible; however, there are logistical and behavioral issues that warrant attention before localized evacuation procedures may be realistic.

Distance Metric Tracking

DTIC Science & Technology

2016-03-02

some close- ness constant and dissimilar pairs be more distant than some larger constant. Online and non -linear extensions to the ITML methodology are...is obtained, instead of solving an objective function formed from the entire dataset. Many online learning methods have regret guarantees, that is... function Metric learning seeks to learn a metric that encourages data points marked as similar to be close and data points marked as different to be far

Hubble 2006: Science Year in Review

NASA Technical Reports Server (NTRS)

Brown, R.

2007-01-01

The 10 science articles selected for this years annual science report exemplify the range of Hubble research from the Solar System, across our Milky Way, and on to distant galaxies. The objects of study include a new feature on Jupiter, binaries in the Kuiper Belt, Cepheid variable stars, the Orion Nebula, distant transiting planets, lensing galaxies, active galactic nuclei, red-and-dead galaxies, and galactic outflows and jets. Each narrative strives to construct the readers understanding of the topics and issues, and to place the latest research in historical, as well as scientific, context. These essays reveal trends in the practice of astronomy. More powerful computers are permitting astronomers to study ever larger data sets, enabling the discovery of subtle effects and rare objects. (Two investigations created mosaic images that are among the largest produced to date.) Multiwavelength data sets from ground-based telescopes, as well as other great observatories Spitzer and Chandraare increasingly important for holistic interpretations of Hubble results. This yearbook also presents profiles of 12 individuals who work with Hubble, or Hubble data, on a daily basis. They are representative of the many students, scientists, engineers, and other professions who are proudly associated with Hubble. Their stories collectively communicate the excitement and reward of careers related to space science and technology.

Perceptual distance and the moon illusion.

PubMed

Kaufman, Lloyd; Vassiliades, Vassias; Noble, Richard; Alexander, Robert; Kaufman, James; Edlund, Stefan

2007-01-01

The elevated moon usually appears smaller than the horizon moon of equal angular size. This is the moon illusion. Distance cues may enable the perceptual system to place the horizon moon at an effectively greater distance than the elevated moon, thus making it appear as larger. This explanation is related to the size-distance invariance hypothesis. However, the larger horizon moon is usually judged as closer than the smaller zenith moon. A bias to expect an apparently large object to be closer than a smaller object may account for this conflict. We designed experiments to determine if unbiased sensitivity to illusory differences in the size and distance of the moon (as measured by d') is consistent with SDIH. A moon above a 'terrain' was compared in both distance and size to an infinitely distant moon in empty space (the reduction moon). At a short distance the terrain moon was adjudged as both closer and smaller than the reduction moon. But these differences could not be detected at somewhat greater distances. At still greater distances the terrain moon was perceived as both more distant and larger than the reduction moon. The distances at which these transitions occurred were essentially the same for both distance and size discrimination tasks, thus supporting SDIH.

Distant stereoacuity in children with anisometropic amblyopia.

PubMed

Chung, Yeon Woong; Park, Shin Hae; Shin, Sun Young

2017-09-01

To characterize changes in distant stereoacuity using Frisby-Davis Distance test (FD2) and Distant Randot test (DR) during treatment for anisometropic amblyopia, to determine factors that influence posttreatment stereoacuity and to compare the two distant stereotests. Fifty-eight anisometropic amblyopic patients with an interocular difference of ≥1.00 diopter who achieved the visual acuity 20/20 following amblyopia treatment were retrospectively included. Stereoacuity using FD2 and DR for distant and Titmus test for near measurement were assessed and compared at the initial, intermediate, and final visit. Multivariate regression models were used to identify factors associated with initial and final stereoacuity. The two distant stereotests revealed a significant improvement in distant stereoacuity after successful amblyopia treatment. Distant stereoacuity using FD2 showed the greatest improvement during the follow up period. The number of nil scores was higher in DR than FD2 at each period. In multivariate analysis, better final stereoacuity was associated with better initial amblyopic eye acuity in both distant stereotests, but not in the Titmus test. Comparing the two distant stereotests, final stereoacuity using FD2 was associated with initial stereoacuity and was moderately related with the Titmus test at each period, but final stereoacuity using DR was not. Distant stereoacuity measured with both FD2 and DR showed significant improvement when the visual acuity of the amblyopic eye achieved 20/20. Changes in distant stereoacuity by FD2 and DR during the amblyopia treatment were somewhat different.

The Anterior Interosseus Artery Perforator Flap: Anatomical Dissections and Clinical Study.

PubMed

Panse, Nikhil S; Joshi, Sheetal B; Sahasrabudhe, Parag B; Bahetee, B; Gurude, Pradnya; Chandanwale, Ajay

2017-05-01

Reconstruction of upper extremity deformities continues to be a challenge to the reconstructive surgeon. Various loco regional, distant and free flaps are available for reconstruction. However, each has its own set of advantages and disadvantages. Of the commonly performed local flaps, radial artery forearm flap, and the posterior interosseus artery flap stand out prominently. Recently, perforator propeller flaps have been used for resurfacing the upper extremity. The anterior interosseus artery perforator flap is an uncommonly used and described flap. This study was divided into anatomical study and clinical application in a IV level of evidence. In the anatomical study, five upper extremities were studied. Clinically, 12 patients underwent reconstruction using the anterior interosseus artery perforator flap. Flaps were performed by a single surgeon. A retrospective review of these cases from November 2008 to May 2014 is presented. The anterior interosseus artery perforator was identified in four out of five cadaver limbs. The septocutaneous perforator was in the fifth extensor compartment around 4 cm proximal to the wrist joint. Of the twelve flaps, there was complete necrosis in one flap, and partial necrosis in one flap. The patient with complete necrosis underwent skin grafting at a later date. The wound healed secondarily in case of partial flap necrosis. Anterior interosseus artery perforator flap must be considered as an important reconstructive option in the armamentarium of the plastic surgeon, while managing hand and wrist defects.

Improving Predictions and Management of Hydrological Extremes

NASA Astrophysics Data System (ADS)

Wijngaard, Janet; Liggins, Felicity; Hurk, Bart vd; Lavers, David; Magnusson, Linus; Bouwer, Laurens; Weerts, Albrecht; Kjellström, Erik; Mañez, Maria; Ramos, Maria-Helena; Hananel, Cedric; Ercin, Ertug; Hunink, Johannes; Klein, Bastian; Pouget, Laurent; de Moel, Hans

2017-04-01

The EU Roadmap on Climate Services can be seen as a result of convergence between society's call for "actionable research" and the climate research community's provision of tailored data, information and knowledge. Although weather and climate have distinct definitions, a strong link between weather and climate services does exist but, to date, this link has not been explored extensively. Stakeholders being interviewed in the context of the Roadmap consider changes in our climate as distant, long-term impacts that are difficult to consider in present-day decision making, a process usually dominated by their daily experience with handling adverse weather and extreme events. However, it could be argued that this experience is a rich source of inspiration to increase society's resilience to an unknown future. The European research project, IMPREX, is built on the notion that "experience in managing present day weather extremes can help us anticipate the consequences of future climate variability and change". This presentation illustrates how IMPREX is building the link between the providers and users of information and services addressing both the weather and climate timescales. For different stakeholders in key economic sectors the needs and vulnerabilities in their daily practice are discussed, followed by an analysis of how weather and climate (W&C) services could contribute to the demands that arise from this. Examples of case studies showing the relevance of the tailored W&C information in users' operations will be included.

Selected highlights from the Extreme Ultraviolet Explorer

NASA Technical Reports Server (NTRS)

Bowyer, S.; Malina, R. F.

1995-01-01

We present a few scientific highlights from the Extreme Ultraviolet Explorer (EUVE) all-sky and deep surveys, from the EUVE Righ Angle Program, and from the EUVE Guest Observer Program. The First EUVE Source Catalog includes 410 extreme ultraviolet (EUV) sources detected in the initial processing of the EUVE all-sky data. A program of optical identification indicates that counterparts include cool star coronae, flare stars, hot white dwarfs, central stars of planetary nebulae, B star photospheres and winds, an X-ray binary, extragalactic objects (active galactic nuclei, BL Lacertae), solar system objects (Moon, Mars, Io,), supernova remnants, and two novae.

Merkel cell carcinoma with seborrheic keratosis: A unique association.

PubMed

Anand, Murthy S; Krishnamurthy, Shantha; Ravindranath, Suvarna; Ranganathan, Jyothi

2018-01-01

Merkel cell carcinoma (MCC) is a rare, clinically aggressive neuroendocrine carcinoma of the skin; MCC is 40 times less common as compared to melanoma. The most frequently reported sites have been the head and neck, extremities, and trunk. Potential mimics include malignant melanoma, lymphoma, or metastatic small cell (neuroendocrine) carcinomas. Histopathology of MCC resembles small cell carcinoma both morphologically and on IHC. The possible cell of origin was proposed as the Merkel cell, which functions as a mechanoreceptor. It has a high chance of local recurrence, regional and distant spread. In recent times, Merkel cell polyomavirus has been implicated as the causative agent for this tumor. The same agent has a reported etiologic association with other skin lesions, including seborrheic keratosis.

Very-Long-Distance Remote Hearing and Vibrometry

NASA Technical Reports Server (NTRS)

Maleki, Lute; Yu, Nan; Matsko, Andrey; Savchenkov, Anatoliy

2009-01-01

A proposed development of laser-based instrumentation systems would extend the art of laser Doppler vibrometry beyond the prior limits of laser-assisted remote hearing and industrial vibrometry for detecting defects in operating mechanisms. A system according to the proposal could covertly measure vibrations of objects at distances as large as thousands of kilometers and could process the measurement data to enable recognition of vibrations characteristic of specific objects of interest, thereby enabling recognition of the objects themselves. A typical system as envisioned would be placed in orbit around the Earth for use as a means of determining whether certain objects on or under the ground are of interest as potential military targets. Terrestrial versions of these instruments designed for airborne or land- or sea-based operation could be similarly useful for military or law-enforcement purposes. Prior laser-based remote-hearing systems are not capable of either covert operation or detecting signals beyond modest distances when operated at realistic laser power levels. The performances of prior systems for recognition of objects by remote vibrometry are limited by low signal-to-noise ratios and lack of filtering of optical signals returned from targets. The proposed development would overcome these limitations. A system as proposed would include a narrow-band laser as its target illuminator, a lock-in-detection receiver subsystem, and a laser-power-control subsystem that would utilize feedback of the intensity of background illumination of the target to adjust the laser power. The laser power would be set at a level high enough to enable the desired measurements but below the threshold of detectability by an imaginary typical modern photodetector located at the target and there exposed to the background illumination. The laser beam would be focused tightly on the distant target, such that the receiving optics would be exposed to only one speckle. The return signal would be extremely-narrow-band filtered (to sub-kilohertz bandwidth) in the optical domain by a whispering-gallery- mode filter so as to remove most of the background illumination. The filtered optical signal would be optically amplified. This combination of optical filtering and optical amplification would provide an optical signal that would be strong enough to be detectable but not so strong as to saturate the detector in the lock-in detection subsystem.

Early and late hot extremes, and elongation of the warm period over Greece

NASA Astrophysics Data System (ADS)

Founda, Dimitra; Giannakopoulos, Christos; Pierros, Fragiskos

2017-04-01

The eastern Mediterranean has been assigned as one of the most responsive areas in climate change, mainly with respect to the occurrence of warmer and drier conditions. In Greece in particular, observations suggest prominent increases in the summer air temperature which in some areas amount to approximately 1 0C/decade since the mid 1970s, while Regional Climate Models simulate further increases in the near and distant future. These changes are coupled with simultaneous increase in the occurrence of hot extremes. In addition to changes in the frequency and intensity of hot extrems, timing of occurrence is also of special interest. Early heat waves in particular, have been found to increase thermal risk in humans. The study explores variations and trends in timing, namely the date of first and last occurrence of hot extremes within the year, and subsequently the hot extremes period (season), defined as the time interval (number of days) between first and last hot extremes occurrence, over Greece. A case study for the area of Athens covering a longer than 100-years period (1897-2015) was conducted first, which will be extended to other Greek areas. Several heat related climatic indices were used, based either on predefined temperature thresholds such as 'tropical days' (daily maximum air temperature, Tmax >30 0C), 'tropical nights' (daily minimum air temperature, Tmin >20 0C), 'hot days' (Tmax >35 0C), or on local climate statistics such as days with Tmax (or Tmin) > 95th percentile. The analysis revealed significant changes in the period of hot extremes and specifically elongation of the period, attributed to early rather than late hot extremes occurrence. An earlier shift of the first tropical day and the first tropical night occurrence by approximately 2 days/decade was found over the study period. An overall elongation of the 'hot days' season by 2.6 days/decade was also observed, which is more prominent since the early 1980s. Over the last three decades, earlier shift of occurrence of days with Tmax > 37 0C and Tmin > 26 0C (corresponding to the 95th percentiles of summer Tmax and Tmin respectively for Athens) was striking, amounting to 8 days/decade. Our findings for the hot extremes period will be used to validate respective simulations of Regional Climate Models downscaled over the areas of interest.

Exploring the Trans-Neptunian Solar System

NASA Astrophysics Data System (ADS)

1998-01-01

A profound question for scientists, philosophers and, indeed, all humans concerns how the solar system originated and subsequently evolved. To understand the solar system's formation, it is necessary to document fully the chemical and physical makeup of its components today, particularly those parts thought to retain clues about primordial conditions and processes.] In the past decade, our knowledge of the outermost, or trans-neptunian, region of the solar system has been transformed as a result of Earth-based observations of the Pluto-Charon system, Voyager 2's encounter with Neptune and its satellite Triton, and recent discoveries of dozens of bodies near to or beyond the orbit of Neptune. As a class, these newly detected objects, along with Pluto, Charon, and Triton, occupy the inner region of a hitherto unexplored component of the solar system, the Kuiper Belt. The Kuiper Belt is believed to be a reservoir of primordial objects of the type that formed in the solar nebula and eventually accreted to form the major planets. The Kuiper Belt is also thought to be the source of short-period comets and a population of icy bodies, the Centaurs, with orbits among the giant planets. Additional components of the distant outer solar system, such as dust and the Oort comet cloud, as well as the planet Neptune itself, are not discussed in this report. Our increasing knowledge of the trans-neptunian solar system has been matched by a corresponding increase in our capabilities for remote and in situ observation of these distant regions. Over the next 10 to 15 years, a new generation of ground- and space-based instruments, including the Keck and Gemini telescopes and the Space Infrared Telescope Facility, will greatly expand our ability to search for and conduct physical and chemical studies on these distant bodies. Over the same time span, a new generation of lightweight spacecraft should become available and enable the first missions designed specifically to explore the icy bodies that orbit 30 astronomical units (AU) or more from the Sun. The combination of new knowledge, plus the technological capability to greatly expand this knowledge over the next decade or so, makes this a particularly opportune time to review current understanding of the trans-neptunian solar system and to begin planning for the future exploration of this distant realm. Based on current knowledge, studies of trans-neptunian objects are important for a variety of reasons that can be summarized under five themes: (1) Exploration of new territory; (2) reservoirs of primitive materials; (3) Processes that reveal the solar system's origin and evolution; (4) Links to extrasolar planets; and (5) prebiotic chemistry. These five themes are not on an equal footing. The first three are well-established areas of scientific investigation and are backed up by a substantial body of observational and theoretical understanding. The last two, however are more speculative. They are included here because they raise a number of interesting possibilities that seem particularly suited to an interdisciplinary approach uniting planetary scientists with their colleagues in the astrophysical and life science communities. Although not considered in any detail in this report, the distant outer solar system also has direct relevance to Earth and the other terrestrial planets because it is the source of comets that bring volatiles into the inner solar system. The resulting inevitable impacts between comets and other planetary bodies can play major roles in the evolution of life as suggested by, for example, the Cretaceous-tertiary boundary bolide and the extinction of the dinosaurs.

Bottlenose dolphins perceive object features through echolocation.

PubMed

Harley, Heidi E; Putman, Erika A; Roitblat, Herbert L

2003-08-07

How organisms (including people) recognize distant objects is a fundamental question. The correspondence between object characteristics (distal stimuli), like visual shape, and sensory characteristics (proximal stimuli), like retinal projection, is ambiguous. The view that sensory systems are 'designed' to 'pick up' ecologically useful information is vague about how such mechanisms might work. In echolocating dolphins, which are studied as models for object recognition sonar systems, the correspondence between echo characteristics and object characteristics is less clear. Many cognitive scientists assume that object characteristics are extracted from proximal stimuli, but evidence for this remains ambiguous. For example, a dolphin may store 'sound templates' in its brain and identify whole objects by listening for a particular sound. Alternatively, a dolphin's brain may contain algorithms, derived through natural endowments or experience or both, which allow it to identify object characteristics based on sounds. The standard method used to address this question in many species is indirect and has led to equivocal results with dolphins. Here we outline an appropriate method and test it to show that dolphins extract object characteristics directly from echoes.

A Glimpse of the Very Early Universal Web

NASA Astrophysics Data System (ADS)

2001-05-01

The VLT Maps Extremely Distant Galaxies Summary New, trailblazing observations with the ESO Very Large Telescope (VLT) at Paranal lend strong support to current computer models of the early universe: It is "spongy", with galaxies forming along filaments, like droplets along the strands of a spiders web. A group of astronomers at ESO and in Denmark [1] determined the distances to some very faint galaxies in the neighbourhood of a distant quasar. Plotting their positions in a three-dimensional map, they found that these objects are located within a narrow "filament", exactly as predicted by the present theories for the development of the first structures in the young universe . The objects are most likely "building blocks" from which galaxies and clusters of galaxies assemble. This observation shows a very useful way forward for the study of the early evolution of the universe and the emergence of structures soon after the Big Bang. At the same time, it provides yet another proof of the great power of the new class of giant optical telescopes for cosmological studies. PR Photo 19a/01 : Web-like structures in the young Universe (computer model). PR Photo 19b/01 : A group of objects at redshift 3.04 . PR Photo 19c/01 : Animated view of sky field and distant filament . PR Photo 19d/01 : The shape of the filament . PR Photo 19e/01 : Artist's impression of the very distant filament. PR Video Clip 04/01 : Video animation of the very distant filament. The computers are ahead of the telescopes For the past two decades cosmologists have been in the somewhat odd situation that their computers were "ahead" of their telescopes. The rapid evolution of powerful computer hardware and sophisticated software has provided theorists with the ability to build almost any sort of virtual universe they can imagine. Starting with different initial conditions just after the Big Bang, they can watch such fictional worlds evolve over billions of years in their supercomputers - and do so in a matter of days only. This has made it possible to predict what the universe might look like when it was still young. And working the opposite way, a comparison between the computer models and the real world might then provide some information about the initial conditions. Unfortunately, until recently astronomical telescopes were not sufficiently powerful to directly study the "real world" of the young universe by observing in detail the extremely faint objects at that early epoch, and thereby to test the predictions. Now, however, the advent of giant telescopes of the 8-10 metre class has changed this situation and a group of astronomers has used the ESO Very Large Telescope (VLT) at Paranal Observatory (Chile) to view a small part of the early cosmic structure. The telescopes have begun to catch up with the computer simulations. First Structures of the Universe ESO PR Photo 19a/01 ESO PR Photo 19a/01 [Preview - JPEG: 353 x 400 pix - 304k] [Normal - JPEG: 706 x 800 pix - 952k] Caption : Computer model of the universe at an age of about 2 billion years (i.e., at redshift 3, see the text). In the simulated universe gravity causes the primordial matter to arrange itself in thin filaments, much like a spider's web. The colour coding indicates the density of the gas, yellow for highest, red for medium, and blue for the lowest density. In the high density (yellow) regions the gas will undergo collapse and ignite bursts of star formation. Those small star-forming regions will slowly stream along the filaments. When they meet at the intersections (the "nodes"), they will merge and cause a gradual build-up of the galaxies we know today. In this sense they are the building blocks of which galaxies are made. This simulated image was computed by Tom Theuns at the Max-Planck-Institute for Astrophysics, Garching, Germany, and kindly made available for this Press Release (please be sure to quote the source). All recent computer-simulations of the early universe have one prediction in common: the first large-scale structures to form in the young universe are long filaments connected at their ends in "nodes" . The models typically look like a three-dimensional spider's web, and resemble the neural structure of a brain ( PR Photo 19a/01 ). The first galaxies or rather, the first galaxy building blocks , will form inside the threads of the web. When they start emitting light, they will be seen to mark out the otherwise invisible threads, much like beads on a string. In the course of millions and billions of years, those early galaxies will stream along these threads, towards and into the "nodes". This is where galaxy clusters will later be formed, cf. ESO PR 13/99. During this process the structure of the universe slowly changes. From being dominated by filaments, it becomes populated by large clusters of galaxies that are still connected by "bridges" and "walls", the last remains of the largest of the original filaments. The Lyman-alpha spectral line New observations with the ESO Very Large Telescope have now identified a string of galaxies that map out a tight filament in the early universe. This trailblazing result is reported by a team of astronomers from ESO and Denmark [1], who have been searching for compact clumps of hydrogen in the early universe. Hydrogen was formed during the Big Bang some 15 billion years ago and is by far the most common element in the universe. When stars are formed by contraction inside a large and compact clump of hydrogen in space, the surrounding hydrogen cloud will absorb the ultraviolet light from the newborn stars, and this cloud will soon start to glow. This glow is mostly emitted at a single wavelength at 121.6 nm (1216 Å), the "Lyman-alpha" emission line of hydrogen. This wavelength is in the ultraviolet part of the spectrum to which the terrestrial atmosphere is totally opaque. Accordingly, the Lyman-alpha emission can normally not be observed by ground-based telescopes. However, if a very distant hydrogen cloud emits Lyman-alpha radiation, then this spectral line will be red-shifted from the ultraviolet into the blue, green or red region of the spectrum [2]. For this reason, observations with large ground-based telescopes of Lyman-alpha radiation can be used to identify faint objects forming inside the high-redshift filaments. The team refers to such objects as the LEGO-blocks of cosmology ("Lyman-alpha Emitting Galaxy-building Objects") [3]. VLT confirms the predictions ESO PR Photo 19b/01 ESO PR Photo 19b/01 [Preview - JPEG: 400 x 276 pix - 95k] [Normal - JPEG: 800 x 551 pix - 216k] [Hi-Res - JPEG: 3000 x 2067 pix - 1.4Mb] ESO PR Photo 19c/01 ESO PR Photo 19c/01 [Animated GIF: 369 x 369 pix - 67k] Caption : PR Photo 19b/01 is a "true-colour" image of part of the sky field near the quasar Q 1205-30 . Red, blue and yellow objects are displayed with their true colours, while objects at a redshift of about 3 and with strong Lyman-alpha emission lines have a bright green colour (see the text). Six Lyman-alpha Emitting Galaxy-building Objects (LEGOs for short) are marked by hexagons. The quasar (at the lower left) is marked by a larger hexagon and is seen to have an extended Lyman-alpha cloud in front of it, here visible as extended green light. In PR Photo 19c/01 , the entire sky field is shown, as observed through the blue filter. The quasar is marked by a red hexagon while the LEGOs are indicated by yellow hexagons. A total of eight objects at redshift 3.04 are identified. One is located in front of the quasar and was found by means of its absorption of the quasar light, while the seven other objects were identified by their Lyman-alpha emission. As explained in the text, all these objects are found to lie inside a thin filament, here visualized in an animated GIF-display. Almost all of the other objects seen in this deep image are either stars in the outskirts of our own Milky Way galaxy or faint galaxies lying between us and the distant filament. Technical information about these photos is available below. Already in 1998, the present team of astronomers obtained very deep images with the ESO 3.58-m New Technology Telescope (NTT) at the La Silla Observatory (Chile) of the sky field around the quasar Q1205-30 . The redshift of this distant object has been measured as z = 3.04, corresponding to a look-back time of about 85% of the age of the Universe. Assuming this to be about 15 billion years, we now observe the quasar as it appeared 13 billion years ago, hence about 2 billion years after the Big Bang. The images were obtained through a special optical filter that only allows light in a narrow spectral waveband to pass. The astronomers chose this wavelength to coincide with that of the Lyman-alpha emission line redshifted to z = 3.04, i.e. 490 nm in the green spectral region. Lyman-alpha radiation from objects at the distance of the quasar - and thus, at nearly the same redshift - will pass through this optical filter. When these images are combined with other deep images taken through much wider red and blue filters, the Lyman-alpha emitting objects at redshift 3.04 will show up as small, intensely green objects, while most other objects in the field will appear in various shades of red, blue and yellow, cf. PR Photo 19b/01 . The spatial distribution of the galaxies ESO PR Photo 19d/01 ESO PR Photo 19d/01 [Preview - JPEG: 400 x 241 pix - 39k] [Normal - JPEG: 800 x 481 pix - 120k] ESO PR Photo 19e/01 ESO PR Photo 19e/01 [Preview - JPEG: 260 x 400 pix - 71k] [Normal - JPEG:5190 x 800 pix - 224k] [Hi-Res - JPEG: 1948 x 3000 pix - 1.5Mb] A Cosmic Filament at z=3.04 - PR Video Clip 04/01 [MPEG - 3.6Mb] ESO PR Video Clip 04/01 "A Cosmic Filament at z=3.04" (May 2001) (1000 frames/40 sec) [MPEG Video; 192x144 pix; 3.6Mb] [MPEG Video; 384x288 pix; 9.6Mb] [RealMedia; streaming; 56kps] [RealMedia; streaming; 200kps] Caption : PR Photo 19d/01 shows the three-dimensional distribution of the observed LEGOs (the hexagons); the three space co-ordinates being determined by the position in the sky and the distance (from the measured redshift, see the text). They are clearly located along a rather narrow filament, here indicated by a hollow cylinder seen from the front (left) and from the side (right). The surrounding box is drawn to facilitate the 3-D comprehension - it measures approximately 8.8 x 8.8 x 13.3 million light-years. PR Photo 19e/01 provides another view of the filament from a different angle, as well as an artist's impression (in colour). The eye represents the viewing angle of the telescope, see also PR Photo 19c/01 . PR Video Clip 04/01 provides an animated view of the spatial configuration of the filaments and the observed objects. Thanks to the great light-gathering capabilily of the VLT and the excellent FORS1 multi-mode instrument at the 8.2-m ANTU telescope, spectra of eight, faint Lyman-alpha objects were obtained in March 2000 that allowed measuring their exact redshifts and hence, their distances [2]. When two co-ordinates from the position in the sky were combined with the measured redshifts into a three-dimensional map, the astronomers found that all of the objects lie within a thin, well-defined filament , cf. PR Photos 19d/01 and 19e/01 . Speaking for the group, Palle Møller is exhilarated: " We have little doubt that for the first time, we are here seeing a small cosmic filament in the early universe. At this enormous distance and correspondingly long look-back time, we see it at a time when the universe was only about 2 billion years old. This is obviously in agreement with the predictions by the computer models of a web-like structure, lending further strong support to our current picture of the early development of the universe in which we live ". Implications of this discovery Does this observation change our view of the early universe? No - on the contrary, it confirms the predictions of computer-models about how cosmic structures formed in the early days after the Big Bang. The most important ingredient in the cosmological models is the dark matter that is believed to contribute about 95% of the mass of the universe. The present confirmation of the predictions of the models therefore also indirectly confirms that it is the dark matter that controls the formation of structures in the universe. However, there is still a long way to go before it will be possible to make a more detailed comparison between observations and predictions, e.g., from PR Photo 19e/01 to PR Photo 19a/01 ! Asked about what they consider the most important consequence of their observations, the team responds: " We have shown that we now have an observational method with which we may study the cosmic web in the early universe, and the VLT is a great tool for such studies. The way forward is now pretty clear - we just have to find those faint and distant LEGOs and then do the spectral observations from which we may determine how they are distributed in space ". More information The research described in this press release is the subject of a scientific article by the team, "Detection of a redshift 3.04 filament" , to appear as a Letter to the Editor in the European journal Astronomy & Astrophysics. Notes [1] The team consists of Palle Møller , Johan Fynbo (both at ESO, Garching) and Bjarne Thomsen (Institute of Physics and Astronomy, Aarhus, Denmark). [2] In astronomy, the redshift denotes the fraction by which the lines in the spectrum of an object are shifted towards longer wavelengths. The observed redshift of a distant hydrogen cloud or galaxy gives a direct estimate of the apparent recession velocity as caused by the universal expansion. Since the expansion rate increases with the distance, the velocity is itself a function (the Hubble relation) of the distance to the object. The higher the redshift of an object, the more distant it is and the longer is the look-back time, i.e. the earlier is the corresponding epoch. [3] See also ESO Press Release 13/99 and ESO Press Release 08/00 (Report F). Technical information about the photos PR Photo 19b/01 is a colour composite, based on three images. The green channel is based on images with a total exposure time of 17.8 hours, obtained through a 2 nm wide, optical filter, centred at wavelength 490.6 nm and obtained in 1998 with the SuSI2 instrument at the ESO 3.58-m New Technology Telescope (NTT) on La Silla. The blue and red channels are based on 13 400-sec exposures in a B-filter and 15 250-sec exposures in an I-filter, respectively, both obtained with 8.2-m VLT ANTU telescope and the multi-mode FORS1 instrument. The field measures 3.0 x 1.8 arcmin 2. North is up and East is left. PR Photo 19c/01 is based on 13 400-sec exposures in a B(lue) optical filter, obtained with VLT ANTU and the multi-mode FORS1 instrument in March 2000. The seeing was 0.7 - 1.0 arcsec and the field measures 6.8 x 6.8 arcmin 2. North is up and East is left.

TIME STRUCTURE OF GAMMA-RAY SIGNALS GENERATED IN LINE-OF-SIGHT INTERACTIONS OF COSMIC RAYS FROM DISTANT BLAZARS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Prosekin, Anton; Aharonian, Felix; Essey, Warren

2012-10-01

Blazars are expected to produce both gamma rays and cosmic rays. Therefore, observed high-energy gamma rays from distant blazars may contain a significant contribution from secondary gamma rays produced along the line of sight by the interactions of cosmic-ray protons with background photons. Unlike the standard models of blazars that consider only the primary photons emitted at the source, models that include the cosmic-ray contribution predict that even {approx}10 TeV photons should be detectable from distant objects with redshifts as high as z {>=} 0.1. Secondary photons contribute to signals of point sources only if the intergalactic magnetic fields aremore » very small, B {approx}< 10{sup -14} G, and their detection can be used to set upper bounds on magnetic fields along the line of sight. Secondary gamma rays have distinct spectral and temporal features. We explore the temporal properties of such signals using a semi-analytical formalism and detailed numerical simulations, which account for all the relevant processes, including magnetic deflections. In particular, we elucidate the interplay of time delays coming from the proton deflections and from the electromagnetic cascade, and we find that, at multi-TeV energies, secondary gamma rays can show variability on timescales of years for B {approx} 10{sup -15} G.« less

An 8-gene qRT-PCR-based gene expression score that has prognostic value in early breast cancer

PubMed Central

2010-01-01

Background Gene expression profiling may improve prognostic accuracy in patients with early breast cancer. Our objective was to demonstrate that it is possible to develop a simple molecular signature to predict distant relapse. Methods We included 153 patients with stage I-II hormonal receptor-positive breast cancer. RNA was isolated from formalin-fixed paraffin-embedded samples and qRT-PCR amplification of 83 genes was performed with gene expression assays. The genes we analyzed were those included in the 70-Gene Signature, the Recurrence Score and the Two-Gene Index. The association among gene expression, clinical variables and distant metastasis-free survival was analyzed using Cox regression models. Results An 8-gene prognostic score was defined. Distant metastasis-free survival at 5 years was 97% for patients defined as low-risk by the prognostic score versus 60% for patients defined as high-risk. The 8-gene score remained a significant factor in multivariate analysis and its performance was similar to that of two validated gene profiles: the 70-Gene Signature and the Recurrence Score. The validity of the signature was verified in independent cohorts obtained from the GEO database. Conclusions This study identifies a simple gene expression score that complements histopathological prognostic factors in breast cancer, and can be determined in paraffin-embedded samples. PMID:20584321

MMP-7 expression may influence the rate of distant recurrences and disease-specific survival in HPV-positive oropharyngeal squamous cell carcinoma.

PubMed

Vento, Seija I; Jouhi, Lauri; Mohamed, Hesham; Haglund, Caj; Mäkitie, Antti A; Atula, Timo; Hagström, Jaana; Mäkinen, Laura K

2018-05-02

The objective of this study was to determine if matrix metalloproteinase-7 (MMP-7) expression is related to human papilloma virus (HPV) status, clinical parameters, and outcome in oropharyngeal squamous cell carcinoma (OPSCC). Tumor tissue specimens from 201 OPSCC patients treated with curative intent were available for immunohistochemistry, and the samples were stained with monoclonal MMP-7 antibody. All the patients were followed up at least 3 years or until death. MMP-7 expression did not differ between HPV-positive and HPV-negative patients. MMP-7 was not prognostic among patients with HPV-negative OPSCC. In the HPV-positive subgroup, patients with moderate, high, or very high MMP-7 expression had significantly worse 5-year disease-specific survival (DSS) (56.6%) than patients with absent, or low MMP-7 expression (77.2%), and MMP-7 expression appeared as a prognostic factor in the multivariate analysis. In addition, among HPV-positive OPSCC with moderate, high, or very high MMP-7 expression, the 5-year distant recurrence-free survival was significantly lower (69.6%) than in those who had low or absent MMP-7 expression (97.5%). Our results suggest that among HPV-positive OPSCC patients, high MMP-7 expression is related to worse 5-year DSS and increased rate of distant recurrences.

Toward An Understanding of Cluster Evolution: A Deep X-Ray Selected Cluster Catalog from ROSAT

NASA Technical Reports Server (NTRS)

Jones, Christine; Oliversen, Ronald (Technical Monitor)

2002-01-01

In the past year, we have focussed on studying individual clusters found in this sample with Chandra, as well as using Chandra to measure the luminosity-temperature relation for a sample of distant clusters identified through the ROSAT study, and finally we are continuing our study of fossil groups. For the luminosity-temperature study, we compared a sample of nearby clusters with a sample of distant clusters and, for the first time, measured a significant change in the relation as a function of redshift (Vikhlinin et al. in final preparation for submission to Cape). We also used our ROSAT analysis to select and propose for Chandra observations of individual clusters. We are now analyzing the Chandra observations of the distant cluster A520, which appears to have undergone a recent merger. Finally, we have completed the analysis of the fossil groups identified in ROM observations. In the past few months, we have derived X-ray fluxes and luminosities as well as X-ray extents for an initial sample of 89 objects. Based on the X-ray extents and the lack of bright galaxies, we have identified 16 fossil groups. We are comparing their X-ray and optical properties with those of optically rich groups. A paper is being readied for submission (Jones, Forman, and Vikhlinin in preparation).

Clinical value of 18 FDG PET/CT in screening for distant metastases in head and neck squamous cell carcinoma.

PubMed

Deurvorst, S E; Hoekstra, O S; Castelijns, J A; Witte, B I; Leemans, C R; de Bree, R

2018-06-01

The detection of distant metastases is of major importance in management of head and neck squamous cell carcinoma patients. All patients underwent 18 FDG PET/CT for the detection of distant metastases. Retrospective single-centre study. Head and neck squamous cell carcinoma patients with high-risk factors for distant metastases. Accuracy of 18 FDG PET/CT for the detection of distant metastases using clinical development of distant metastases and a minimal follow-up of twelve months as reference standard. Comparison of overall survival between patients diagnosed with distant metastases during initial screening and patients diagnosed with distant metastases during follow-up. In 23 (12%) of the 190 patients, 18 FDG PET/CT detected distant metastases at screening. Sensitivity and negative predictive value were 46.2% (95% CI 32.6-59.7) and 82.6% (95% CI 76.8-88.5). No difference in median overall survival from the time of distant metastases detection was found between patients diagnosed with DM during work-up or during follow-up. In head and neck squamous cell carcinoma patients with high-risk factors, 18 FDG PET/CT has a high negative predictive value for the detection of distant metastases and should be used in daily clinical practice, although the sensitivity is limited when long-term follow-up is used as reference standard. © 2018 The Authors. Clinical Otolaryngology Published by John Wiley & Sons Ltd.

Biology of North American tortoises

USGS Publications Warehouse

Bury, R. Bruce; Germano, David J.

1994-01-01

Chelonians have fascinated people for centuries and have been the object of biological studies for nearly as long. Perhaps the long life span and harmless demeanor of most species contribute to their wide appeal. they also represent a link to the distant past because their characteristic shell separated this line of ectotherms from all other reptiles and all other animals in the age of dinosaurs (Pough et al. 1989). However, the origins of chelonians remain a mystery.

Eyeglass Filters

NASA Technical Reports Server (NTRS)

1987-01-01

Biomedical Optical Company of America's suntiger lenses eliminate more than 99% of harmful light wavelengths. NASA derived lenses make scenes more vivid in color and also increase the wearer's visual acuity. Distant objects, even on hazy days, appear crisp and clear; mountains seem closer, glare is greatly reduced, clouds stand out. Daytime use protects the retina from bleaching in bright light, thus improving night vision. Filtering helps prevent a variety of eye disorders, in particular cataracts and age related macular degeneration.

Static black holes with back reaction from vacuum energy

NASA Astrophysics Data System (ADS)

Ho, Pei-Ming; Matsuo, Yoshinori

2018-03-01

We study spherically symmetric static solutions to the semi-classical Einstein equation sourced by the vacuum energy of quantum fields in the curved space-time of the same solution. We found solutions that are small deformations of the Schwarzschild metric for distant observers, but without horizon. Instead of being a robust feature of objects with high densities, the horizon is sensitive to the energy–momentum tensor in the near-horizon region.

Helicopter Aircrew Training Using Fused Reality

DTIC Science & Technology

2006-06-01

PROCESS Blue screening involving human filming usually employs a blue or green backdrop, since skin contains little blue or green hue. These backdrops...Helicopter Aircrew Training Using Fused Reality 27 - 10 RTO-MP-HFM-136 a. b. c. d. e. f. Figure 13: Frames Showing Physical Object ( witch ... filming . However, when a user’s hands disrupt the light from a helmet-mounted light source, the shadows cast onto the distant background are diffuse and

Hot stars in young massive clusters: Mapping the current Galactic metallicity

NASA Astrophysics Data System (ADS)

de la Fuente, Diego; Najarro, Francisco; Davies, Ben; Trombley, Christine; Figer, Donald F.; Herrero, Artemio

2013-06-01

Young Massive Clusters (YMCs) with ages < 6 Myr are ideal tools for mapping the current chemical abundances in the Galactic disk for several reasons. First of all, the locations of these clusters can be known through spectrophotometric distances. Secondly, their young ages guarantee that these objects present the same chemical composition than the surrounding environment where they are recently born. Finally, the YMCs host very massive stars whose extreme luminosities allow to accomplish detailed spectroscopic analyses even in the most distant regions of the Milky Way. Our group has carried out ISAAC/VLT spectroscopic observations of hot massive stars belonging to several YMCs in different locations around the Galactic disk. As a result, high signal-to-noise, near-infrared spectra of dozens of blue massive stars (including many OB supergiants, Wolf-Rayet stars and a B hypergiant) have been obtained. These data are fully reduced, and NLTE spherical atmosphere modeling is in process. Several line diagnostics will be combined in order to calculate metal abundances accurately for each cluster. The diverse locations of the clusters will allow us to draw a two-dimensional chemical map of the Galactic disk for the first time. The study of the radial and azimuthal variations of elemental abundances will be crucial for understanding the chemical evolution of the Milky Way. Particularly, the ratio between Fe-peak and alpha elements will constitute a powerful tool to investigate the past stellar populations that originated the current Galactic chemistry.

RELICS: A Candidate Galaxy Arc at z~10 and Other Brightly Lensed z>6 Galaxies

NASA Astrophysics Data System (ADS)

Salmon, Brett; Coe, Dan; Bradley, Larry; Bradac, Marusa; Huang, Kuang-Han; Oesch, Pascal; Brammer, Gabriel; Stark, Daniel P.; Sharon, Keren; Trenti, Michele; Avila, Roberto J.; Ogaz, Sara; Acebron, Ana; Andrade-Santos, Felipe; Carrasco, Daniela; Cerny, Catherine; Cibirka, Nathália; Dawson, William; Frye, Brenda; Hoag, Austin; Jones, Christine; Mainali, Ramesh; Ouchi, Masami; Paterno-Mahler, Rachel; Rodney, Steven; Umetsu, Keiichi; Zitrin, Adi; RELICS

2018-01-01

Massive foreground galaxy clusters magnify and distort the light of objects behind them, permitting a view into both the extremely distant and intrinsically faint galaxy populations. We present here some of the most brightly lensed z>6 galaxy candidates known from the Reionization Lensing Cluster Survey (RELICS) and the discovery of a particularly fortuitous z~10 galaxy candidate which has been arced by the effects of strong gravitational lensing. The z~10 candidate has a lensed H-band magnitude of 25.8 AB mag and a high lensing magnification (~4-7). The inferred upper limits on the stellar mass (log [M_star /M_Sun]=9.5) and star formation rate (log [SFR/(M_Sun/yr)]=1.5) indicate that this candidate is a typical star-forming galaxy on the z>6 SFR-M_star relation. We rule out the only low-z solution as unphysical based on the required stellar mass, dust attenuation, size, and [OIII] EW needed for a z~2 SED to match the data. Finally, we reconstruct the source-plane image and estimate the candidate's physical size at z~10, finding a half-light radius of r_e < 0.8 kpc that is in line with the sizes of other z>9 candidates. While the James Webb Space Telescope will detect z>10 with ease, this rare candidate offers the potential for unprecedented spatial resolution less than 500 Myr after the Big Bang.

Differences in Self-Reported Physical Limitation Among Older Women and Men in Ismailia, Egypt

PubMed Central

2012-01-01

Objectives. This study explores the reasons for gender differences in self-reported physical limitation among older adults in Ismailia, Egypt. Method. 435 women and 448 men, 50 years and older in Ismailia, Egypt, participated in a social survey and tests of physical performance. Ordered logit models were estimated to compare unadjusted gender differences in reported disability with these differences adjusted sequentially for (a) age and objective measures of physical performance, (b) self-reported morbidities and health care use, and (c) social and economic attributes. Results. Compared with men, women more often reported higher levels of limitation in activities of daily living (ADLs), upper-extremity range of motion (ROM), and lower-extremity gross mobility (GM). Adjusting for age and objective measures of physical performance, women and men had similar odds of self-reporting difficulty with ADLs. With sequential adjustments for the remaining variables, women maintained significantly higher odds of self-reported difficulty with upper-extremity ROM and lower-extremity GM. Discussion. Cross-culturally, gender differences in self-reported disability may arise from objective and subjective perceptions of disability. Collectively, these results and those from prior studies in Bangladesh and the United States suggest that gender gaps in self-reported physical limitation may be associated with the degree of gender equality in society. PMID:22929399

Biogeography in Cellana (Patellogastropoda, Nacellidae) with Special Emphasis on the Relationships of Southern Hemisphere Oceanic Island Species.

PubMed

González-Wevar, Claudio A; Nakano, Tomoyuki; Palma, Alvaro; Poulin, Elie

2017-01-01

Oceanic islands lacking connections to other land are extremely isolated from sources of potential colonists and have acquired their biota mainly through dispersal from geographically distant areas. Hence, isolated island biota constitutes interesting models to infer biogeographical mechanisms of dispersal, colonization, differentiation, and speciation. Limpets of the genus Cellana (Nacellidae: Patellogastropoda) show limited dispersal capacity but are broadly distributed across the Indo-Pacific including many endemic species in isolated oceanic islands. Here, we examined main distributional patterns and geographic boundaries among Cellana lineages with special emphasis in the relationships of Southern Hemisphere oceanic islands species. Phylogenetic reconstructions based on mtDNA (COI) recognized three main clades in Cellana including taxa from different provinces of the Indo-Pacific. Clear genetic discontinuities characterize the biogeography of Cellana and several lineages are associated to particular areas of the Indo-Pacific supporting the low dispersal capacity of the genus across recognized biogeographical barriers in the region. However, evolutionary relationships within Cellana suggest that long-distance dispersal processes have been common in the history of the genus and probably associated to the origin of the species in Hawaii and Juan Fernández Archipelago. Therefore, the presence of Cellana species in geographically distant Southern Hemisphere oceanic islands, such as the Juan Fernández Archipelago, suggests that long-distance dispersal mediated by rafting may have played an important role in the biogeography of the genus.

The clustering evolution of distant red galaxies in the GOODS-MUSIC sample

NASA Astrophysics Data System (ADS)

Grazian, A.; Fontana, A.; Moscardini, L.; Salimbeni, S.; Menci, N.; Giallongo, E.; de Santis, C.; Gallozzi, S.; Nonino, M.; Cristiani, S.; Vanzella, E.

2006-07-01

Aims.We study the clustering properties of Distant Red Galaxies (DRGs) to test whether they are the progenitors of local massive galaxies. Methods.We use the GOODS-MUSIC sample, a catalog of ~3000 Ks-selected galaxies based on VLT and HST observation of the GOODS-South field with extended multi-wavelength coverage (from 0.3 to 8~μm) and accurate estimates of the photometric redshifts to select 179 DRGs with J-Ks≥ 1.3 in an area of 135 sq. arcmin.Results.We first show that the J-Ks≥ 1.3 criterion selects a rather heterogeneous sample of galaxies, going from the targeted high-redshift luminous evolved systems, to a significant fraction of lower redshift (1

Ranking Medical Terms to Support Expansion of Lay Language Resources for Patient Comprehension of Electronic Health Record Notes: Adapted Distant Supervision Approach

PubMed Central

Jagannatha, Abhyuday N; Fodeh, Samah J; Yu, Hong

2017-01-01

Background Medical terms are a major obstacle for patients to comprehend their electronic health record (EHR) notes. Clinical natural language processing (NLP) systems that link EHR terms to lay terms or definitions allow patients to easily access helpful information when reading through their EHR notes, and have shown to improve patient EHR comprehension. However, high-quality lay language resources for EHR terms are very limited in the public domain. Because expanding and curating such a resource is a costly process, it is beneficial and even necessary to identify terms important for patient EHR comprehension first. Objective We aimed to develop an NLP system, called adapted distant supervision (ADS), to rank candidate terms mined from EHR corpora. We will give EHR terms ranked as high by ADS a higher priority for lay language annotation—that is, creating lay definitions for these terms. Methods Adapted distant supervision uses distant supervision from consumer health vocabulary and transfer learning to adapt itself to solve the problem of ranking EHR terms in the target domain. We investigated 2 state-of-the-art transfer learning algorithms (ie, feature space augmentation and supervised distant supervision) and designed 5 types of learning features, including distributed word representations learned from large EHR data for ADS. For evaluating ADS, we asked domain experts to annotate 6038 candidate terms as important or nonimportant for EHR comprehension. We then randomly divided these data into the target-domain training data (1000 examples) and the evaluation data (5038 examples). We compared ADS with 2 strong baselines, including standard supervised learning, on the evaluation data. Results The ADS system using feature space augmentation achieved the best average precision, 0.850, on the evaluation set when using 1000 target-domain training examples. The ADS system using supervised distant supervision achieved the best average precision, 0.819, on the evaluation set when using only 100 target-domain training examples. The 2 ADS systems both performed significantly better than the baseline systems (P<.001 for all measures and all conditions). Using a rich set of learning features contributed to ADS’s performance substantially. Conclusions ADS can effectively rank terms mined from EHRs. Transfer learning improved ADS’s performance even with a small number of target-domain training examples. EHR terms prioritized by ADS were used to expand a lay language resource that supports patient EHR comprehension. The top 10,000 EHR terms ranked by ADS are available upon request. PMID:29089288

Giant Cosmic Lens Reveals Secrets of Distant Galaxy

NASA Astrophysics Data System (ADS)

2003-04-01

Using the National Science Foundation's Very Large Array (VLA) radio telescope and helped by a gigantic cosmic lens conveniently provided by nature, an international team of astronomers has discovered that a young galaxy had a central disk of gas in which hundreds of new stars were being born every year -- at a time when the Universe was only a fraction of its current age. Artist's Conception of the Star-Forming Disk (Click on Image for Larger Version) VLA Image of PSS J2322+1944 (Click on Image for Larger Version) "This unique look into a very distant, young galaxy gives us unprecedented insight into the process that produced both tremendous numbers of stars and supermassive black holes in forming galaxies," said Chris Carilli, of the National Radio Astronomy Observatory (NRAO) in Socorro, NM, leader of the research team. "This work strongly supports the idea that the stars and the black holes formed simultaneously," he added. The research was published in the April 4 issue of Science Express. The astronomers studied a quasar called PSS J2322+1944, about 12 billion light-years from Earth. The quasar is an extremely luminous object powered by the supermassive black hole at the core of a galaxy. At the distance of this quasar, the scientists see the object as it was when the Universe was less than 2 billion years old, about 15 percent of its current age. The discovery required a huge assist from nature. To find the star-forming disk, the astronomers needed to observe natural radio emission from the carbon monoxide (CO) molecule, an important component of the gas that forms stars. However, this molecule emits radio waves at frequencies much higher than the VLA is capable of receiving. At PSS J2322+1944's distance of 12 billion light-years, however, the expansion of the Universe stretched the radio waves, reducing their frequency. CO emission at 230 GigaHertz was shifted to 45 GigaHertz, within the VLA's range. That alone was not enough. The distance that made it possible to receive the radio waves from the quasar also meant that the object was too far away for the VLA to discern the detail required to show the disk. Once again, nature stepped in to help, providing another galaxy directly between the quasar and Earth to form a gravitational lens. "What we needed wasn't just any old gravitational lens, but a nearly-perfect alignment of the distant quasar, mid-distance galaxy, and Earth -- and that's what we got," said Geraint Lewis of the University of Sydney in Australia, another member of the team. With such a perfect alignment, the quasar image was distorted into a ring, called an "Einstein Ring." The VLA images were the first to show the Einstein Ring of PSS J2322+1944. "We never would have seen the disk of CO gas near the center of this galaxy without the gravitational lens," said Carilli. "The lens boosted the signal and magnified the image to reveal the disk's structure in unprecedented detail," he added. For several years, astronomers have noted that the masses of black holes are directly proportional to the sizes of central bulges of stars in galaxies. This led to the speculation that formation of the black holes and of the stars are somehow related to each other. Scientists hypothesized that gas being drawn towards a galaxy's central black hole is the same gas from which large numbers of stars are forming. Studies of more-nearby galaxies supported such speculation, but the question remained whether the idea could be applied to the very early Universe, when the first galaxies and black holes formed. "This new observation gives strong support to the idea that large numbers of stars were forming in young galaxies at the same time that their central black holes were pulling in additional mass," said Pierre Cox, of the Institute for Space Astrophysics of the University of Paris. The astronomers believe that galaxies in the early Universe were frequently disrupted by nearby encounters with other galaxies, "feeding" the central black hole with gas. The gas formed an extensive, spinning disk around the galaxy's center, some of it eventually falling into the black hole and some of it forming new stars. In PSS J2322+1944, the astronomers believe that new stars with a total mass equal to some 900 times that of the Sun were forming in the 13,000-light-year-diameter disk every year. At that rate, the scientists say, most of the stars in a large elliptical galaxy could form in only about 100 million years. PSS J2322+1944 is one of the most luminous quasars in the Universe. It was first discovered by George Djorgovski and his collaborators from the California Institute of Technology (Caltech), using the digitized Palomar Observatory Sky Survey. Later studies led by Cox and Alain Omont of the Astrophysical Institute of Paris using the IRAM millimeter-wave facilities in Europe (the 30-meter telescope and the Plateau de Bure Interferometer) showed that it had a huge reservoir of dust and molecular gas, the fuel for star formation. Optical observation at the W.M. Keck Observatory in Hawaii showed a double image that indicated gravitational lensing. All these factors, the scientists said, made it an ideal candidate for study with the VLA. "Our guess paid off handsomely. Finding that Einstein Ring with the VLA gave us the tool we needed to see what was going on inside that very distant galaxy," said Carilli. "There are fewer than 100 gravitational lenses known so far, and we were extremely lucky to find one that allowed us to help resolve the specific scientific question we were studying." Gravitational lenses were predicted, based on Albert Einstein's General Theory of Relativity, in 1919. Einstein himself showed in 1936 that a perfectly-aligned gravitational lens would produce a circular image, but felt that the chances of actually observing such an object were nearly zero. The first gravitational lens was discovered in 1979, and the first Einstein Ring was discovered by researchers using the VLA in 1987. PSS J2322+1944 is the first Einstein Ring detected through the signature emission of a molecule and the most distant yet found. PSS J2322+1944 may be able to make another contribution to science. Astronomers believe that gravitational lenses may serve as a tool for precisely measuring great distances in the Universe. If a distant quasar varies in brightness over time, the multiple images formed by a gravitational lens would show that variation at different times. By monitoring such time differences and using a mathematical model of the specific gravitational lens, the distance to the quasar can be measured. "This quasar, if it shows brightness variations in the future, may be such a 'Golden Lens,' long sought to refine our measurement of very great distances," said Lewis. In addition to Carilli, Lewis, Djorgovski, Cox and Omont, the research team includes Ashish Mahabal of Caltech and Frank Bertoldi of the Max-Planck Institute for Radio Astronomy in Bonn, Germany. The National Radio Astronomy Observatory is a facility of the National Science Foundation, operated under cooperative agreement by Associated Universities, Inc.

Multi-Object Spectroscopy with MUSE

NASA Astrophysics Data System (ADS)

Kelz, A.; Kamann, S.; Urrutia, T.; Weilbacher, P.; Bacon, R.

2016-10-01

Since 2014, MUSE, the Multi-Unit Spectroscopic Explorer, is in operation at the ESO-VLT. It combines a superb spatial sampling with a large wavelength coverage. By design, MUSE is an integral-field instrument, but its field-of-view and large multiplex make it a powerful tool for multi-object spectroscopy too. Every data-cube consists of 90,000 image-sliced spectra and 3700 monochromatic images. In autumn 2014, the observing programs with MUSE have commenced, with targets ranging from distant galaxies in the Hubble Deep Field to local stellar populations, star formation regions and globular clusters. This paper provides a brief summary of the key features of the MUSE instrument and its complex data reduction software. Some selected examples are given, how multi-object spectroscopy for hundreds of continuum and emission-line objects can be obtained in wide, deep and crowded fields with MUSE, without the classical need for any target pre-selection.

Photometric observations of nine Transneptunian objects and Centaurs

NASA Astrophysics Data System (ADS)

Hromakina, T.; Perna, D.; Belskaya, I.; Dotto, E.; Rossi, A.; Bisi, F.

2018-02-01

We present the results of photometric observations of six Transneptunian objects and three Centaurs, estimations of their rotational periods and corresponding amplitudes. For six of them we present also lower limits of density values. All observations were made using 3.6-m TNG telescope (La Palma, Spain). For four objects - (148975) 2001 XA255, (281371) 2008 FC76, (315898) 2008 QD4, and 2008 CT190 - the estimation of short-term variability was made for the first time. We confirm rotation period values for two objects: (55636) 2002 TX300 and (202421) 2005 UQ513, and improve the precision of previously reported rotational period values for other three - (120178) 2003 OP32, (145452) 2005 RN43, (444030) 2004 NT33 - by using both our and literature data. We also discuss here that small distant bodies, similar to asteroids in the Main belt, tend to have double-peaked rotational periods caused by the elongated shape rather than surface albedo variations.

Metastatic patterns and metastatic sites in mucosal melanoma: a retrospective study.

PubMed

Grözinger, Gerd; Mann, Steven; Mehra, Tarun; Klumpp, Bernhard; Grosse, Ulrich; Nikolaou, Konstantin; Garbe, Claus; Clasen, Stephan

2016-06-01

Melanomas arising from mucosa are rare and associated with a poor prognosis. This study aims to provide an analysis of metastatic pathways, time intervals, factors influencing metastatic spread and organs for distant metastases. A total of 116 patients with mucosal melanomas of different sites were included. The mean follow-up interval was 47 ± 52 months. Patients were assigned to two different metastatic pathways, either presenting loco-regional lymph node metastases as first spread or direct distant metastases. The distribution of distant metastases was assessed. Twenty-six patients presented with a pre-existing metastatic spread and were not assigned to pathways. Of the included patients, 44 developed metastases after treatment of the primary tumour; 25 patients directly developed distant metastases; 16 patients developed regional lymph node metastases prior to distant metastases. Location of the primary tumour in the upper airway or GI tract and advanced T stage were significant risk factors of direct distant metastases. Distant metastases are mainly located in the lung, the liver and non-regional lymph nodes. Mucosal melanomas show a high rate of direct distant metastases rather than regional lymph node metastases. Thus the follow-up should always include a whole-body cross-sectional imaging in high-risk tumours. • Mucosal melanomas show a high rate of direct distant metastases. • T stage and primary location are predictors for direct distant metastases. • Distant metastases were mainly found in lung, liver and lymph nodes. • Follow-up of a high-risk mucosal melanoma should include whole-body imaging.

Extended Source/Galaxy All Sky 1

NASA Image and Video Library

2003-03-27

This panoramic view of the entire sky reveals the distribution of galaxies beyond our Milky Way galaxy, which astronomers call extended sources, as observed by Two Micron All-Sky Survey. The image is constructed from a database of over 1.6 million galaxies listed in the survey's Extended Source Catalog; more than half of the galaxies have never before been catalogued. The image is a representation of the relative brightnesses of these million-plus galaxies, all observed at a wavelength of 2.2 microns. The brightest and nearest galaxies are represented in blue, and the faintest, most distant ones are in red. This color scheme gives insights into the three dimensional large-scale structure of the nearby universe with the brightest, closest clusters and superclusters showing up as the blue and bluish-white features. The dark band in this image shows the area of the sky where our Milky Way galaxy blocks our view of distant objects, which, in this projection, lies predominantly along the edges of the image. http://photojournal.jpl.nasa.gov/catalog/PIA04252

Stellar Population and Star Formation History of the Distant Galactic H II Regions NGC 2282 and Sh2-149

NASA Astrophysics Data System (ADS)

Dutta, S.; Mondal, S.; Jose, J.; Das, R. K.

2017-06-01

We present here the recent results on two distant Galactic H II regions, namely NGC 2282 and Sh2-149, obtained with multiwavelength observations. Our optical spectroscopic analysis of the bright sources have been used to identify the massive members, and to derive the fundamental parameters such as age and distance of these regions. Using IR color-color criteria and Hα-emission properties, we have identified and classified the candidate young stellar objects (YSOs) in these regions. The 12CO(1-0) continuum maps along with the K-band extinction maps, and spatial distribution of YSOs are used to investigate the structure and morphology of the molecular cloud associated with these H II regions. Overall analysis of these regions suggests that the star formation occurs at the locations of the denser gas, and we also find possible evidences of the induced star formation due to the feedback from massive stars to its surrounding molecular medium.

Galaxy evolution. Quasar quartet embedded in giant nebula reveals rare massive structure in distant universe.

PubMed

Hennawi, Joseph F; Prochaska, J Xavier; Cantalupo, Sebastiano; Arrigoni-Battaia, Fabrizio

2015-05-15

All galaxies once passed through a hyperluminous quasar phase powered by accretion onto a supermassive black hole. But because these episodes are brief, quasars are rare objects typically separated by cosmological distances. In a survey for Lyman-α emission at redshift z ≈ 2, we discovered a physical association of four quasars embedded in a giant nebula. Located within a substantial overdensity of galaxies, this system is probably the progenitor of a massive galaxy cluster. The chance probability of finding a quadruple quasar is estimated to be ∼10(-7), implying a physical connection between Lyman-α nebulae and the locations of rare protoclusters. Our findings imply that the most massive structures in the distant universe have a tremendous supply (≃10(11) solar masses) of cool dense (volume density ≃ 1 cm(-3)) gas, which is in conflict with current cosmological simulations. Copyright © 2015, American Association for the Advancement of Science.

A Dwarf Planet Class Object in the 21:5 Resonance with Neptune

NASA Astrophysics Data System (ADS)

Holman, Matthew J.; Payne, Matthew J.; Fraser, Wesley; Lacerda, Pedro; Bannister, Michele T.; Lackner, Michael; Chen, Ying-Tung; Lin, Hsing Wen; Smith, Kenneth W.; Kokotanekova, Rosita; Young, David; Chambers, K.; Chastel, S.; Denneau, L.; Fitzsimmons, A.; Flewelling, H.; Grav, Tommy; Huber, M.; Induni, Nick; Kudritzki, Rolf-Peter; Krolewski, Alex; Jedicke, R.; Kaiser, N.; Lilly, E.; Magnier, E.; Mark, Zachary; Meech, K. J.; Micheli, M.; Murray, Daniel; Parker, Alex; Protopapas, Pavlos; Ragozzine, Darin; Veres, Peter; Wainscoat, R.; Waters, C.; Weryk, R.

2018-03-01

We report the discovery of an H r = 3.4 ± 0.1 dwarf planet candidate by the Pan-STARRS Outer Solar System Survey. 2010 JO179 is red with (g ‑ r) = 0.88 ± 0.21, roughly round, and slowly rotating, with a period of 30.6 hr. Estimates of its albedo imply a diameter of 600–900 km. Observations sampling the span between 2005 and 2016 provide an exceptionally well determined orbit for 2010 JO179, with a semimajor axis of 78.307 ± 0.009 au; distant orbits known to this precision are rare. We find that 2010 JO179 librates securely within the 21:5 mean-motion resonance with Neptune on 100 Myr timescales, joining the small but growing set of known distant dwarf planets on metastable resonant orbits. These imply a substantial trans-Neptunian population that shifts between stability in high-order resonances, the detached population, and the eroding population of the scattering disk.

Pain thresholds and tenderness in neck and head following acute whiplash injury: a prospective study.

PubMed

Kasch, H; Stengaard-Pedersen, K; Arendt-Nielsen, L; Staehelin Jensen, T

2001-04-01

OBJECTIVE OF THE INVESTIGATION: In a 6-month prospective study of 141 consecutive acute whiplash-injured participants, and 40 acute, ankle-injured controls, pain and tenderness in the neck/head, and at a distant control site, were measured. Muscle palpation and pressure algometry in five head/neck muscle-pairs were performed after 1 week and 1, 3 and 6 months after injury. Algometry was performed at a distant control site. Whiplash-injured patients had lowered pressure-pain-detection thresholds and higher palpation-score initially in the neck/head, but the groups were similar after 6 months, and the control site was not sensitized. Focal, but not generalized, sensitization to musculoskeletal structure is present until 3 months, but not 6 months, after whiplash injury, and probably does not play a major role in the development of late whiplash syndrome. Pressure algometry and palpation are useful clinical tools in the evaluation of neck and jaw pain in acute whiplash injury.

A high-frequency survey of the southern Galactic plane for pulsars

NASA Technical Reports Server (NTRS)

Johnston, Simon; Lyne, A. G.; Manchester, R. N.; Kniffen, D. A.; D'Amico, N.; Lim, J.; Ashworth, M.

1992-01-01

Results of an HF survey designed to detect young, distant, and short-period pulsars are presented. The survey detected a total of 100 pulsars, 46 of which were previously unknown. The periods of the newly discovered pulsars range between 47 ms and 2.5 ms. One of the new discoveries, PSR 1259-63, is a member of a long-period binary system. At least three of the pulsars have ages less than 30,000 yr, bringing the total number of such pulsars to 12. The majority of the new discoveries are distant objects with high dispersion measures, which are difficult to detect at low frequencies. This demonstrates that the survey has reduced the severe selection effects of pulse scattering, high Galactic background temperature, and dispersion broadening, which hamper the detection of such pulsars at low radio frequencies. The pulsar distribution in the southern Galaxy is found to extend much further from the Galactic center than that in the north, probably due to two prominent spiral arms in the southern Galaxy.

[Therapy of malignant melanoma at the stage of distant metastasis].

PubMed

Garbe, C; Eigentler, T K

2004-02-01

Treatment of melanoma in the stage of distant metastasis aims on palliation and achievement of durable tumor remission with prolongation of survival. As long as metastasis is confined to one organ system and is removable, surgery remains the treatment of first choice. In limited metastasis radiotherapy may likewise be indicated, particularly in bone and brain metastasis. More extensive metastasis should be treated by chemotherapy or chemoimmunotherapy. Monochemotherapy with dacarbazine, temozolomide, fotemustine and vindesine or its combinations with interferon-alpha are currently preferred. Polychemotherapy or its combinations with interferon-alpha and interleukin-2 are suitable to produce higher response rates but failed to prolong survival. As these treatments are associated with substantially higher toxicity they have been widely abandoned. Combined treatment with dacarbazine and interferon-alpha obtain tumor responses or stable disease in 40-50% and objective tumor remissions in 15-20% of patients. Effective cancer vaccination strategies and blockade of melanoma specific target molecules are currently developed as new treatment options.

Distinguishing Buried Objects in Extremely Shallow Underground by Frequency Response Using Scanning Laser Doppler Vibrometer

NASA Astrophysics Data System (ADS)

Abe, Touma; Sugimoto, Tsuneyoshi

2010-07-01

A sound wave vibration using a scanning laser Doppler vibrometer are used as a method of exploring and imaging an extremely shallow underground. Flat speakers are used as a vibration source. We propose a method of distinguishing a buried object using a response range of a frequencies corresponding to a vibration velocities. Buried objects (plastic containers, a hollow steel can, an unglazed pot, and a stone) are distinguished using a response range of frequencies. Standardization and brightness imaging are used as methods of discrimination. As a result, it was found that the buried objects show different response ranges of frequencies. From the experimental results, we confirmed the effectiveness of our proposed method.

Techniques that Link Extreme Events to the Large Scale, Applied to California Heat Waves

NASA Astrophysics Data System (ADS)

Grotjahn, R.

2015-12-01

Understanding the mechanisms how Californian Central Valley (CCV) summer extreme hot spells develop is very important since the events have major impacts on the economy and human safety. Results from a series of CCV heat wave studies will be presented, emphasizing the techniques used. Key larger scale elements are identified statistically that are also consistent with synoptic and dynamic understanding of what must be present during extreme heat. Beyond providing a clear synoptic explanation, these key elements have high predictability, in part because soil moisture has little annual variation in the heavily-irrigated CCV. In turn, the predictability naturally leads to an effective tool to assess climate model simulation of these heat waves in historical and future climate scenarios. (Does the model develop extreme heat for the correct reasons?) Further work identified that these large scale elements arise in two quite different ways: one from expansion southwestward of a pre-existing heat wave in southwest Canada, the other formed in place from parcels traversing the North Pacific. The pre-existing heat wave explains an early result showing correlation between heat waves in Sacramento California, and other locations along the US west coast, including distant Seattle Washington. CCV heat waves can be preceded by unusually strong tropical Indian Ocean and Indonesian convection, this partial link may occur through an Asian subtropical jet wave guide. Another link revealed by diagnostics is a middle and higher latitude source of wave activity in Siberia and East Asia that also leads to the development of the CCV heat wave. This talk will address as many of these results and the tools used to obtain them as is reasonable within the available time.

Selections from 2017: Mapping the Universe with SDSS-IV

NASA Astrophysics Data System (ADS)

Kohler, Susanna

2017-12-01

Editors note:In these last two weeks of 2017, well be looking at a few selections that we havent yet discussed on AAS Nova from among the most-downloaded paperspublished in AAS journals this year. The usual posting schedule will resume in January.Sloan Digital Sky Survey IV: Mapping the Milky Way, Nearby Galaxies, and the Distant UniversePublished June2017Main takeaway:The incredibly prolific Sloan Digital Sky Survey has provided photometric observations of around 500 million objects and spectra for more than 3 million objects. The survey has now entered its fourth iteration, SDSS-IV, with the first public data release made in June 2016. A publication led by Michael Blanton (New York University) describes the facilities used for SDSS-IV, its science goals, and itsthree coreprograms.Why its interesting:Since data collection began in 2000, SDSS has been one of the premier surveysproviding imaging and spectroscopy for objects in both the near and distant universe.SDSS has measured spectra not only for the stars in our own Milky Way, but also for galaxies that lie more than 7 billion light-years distant making itan extremelyuseful and powerful tool for mapping our universe.What SDSS-IV is looking for:SDSS image of an example MaNGA target galaxy (left), with some of the many things we can learn about it shown in the right and bottom panels: stellar velocity dispersion, stellar mean velocity, stellar population age, metallicity, etc. [Blanton et al. 2017]SDSS-IV containsthree core programs:Apache Point Observatory Galactic Evolution Experiment 2 (APOGEE-2)provides high-resolution near-infrared spectra of hundreds of thousands of Milky-Way stars with the goal ofimproving our understanding of the history of the Milky Way and of stellar astrophysics.Mapping Nearby Galaxies at Apache Point Observatory (MaNGA)obtains spatially resolved spectra for thousands of nearby galaxiesto better understand the evolutionary histories of galaxies and what regulates their star formation.Extended Baryon Oscillation Spectroscopic Survey (eBOSS)mapsthe galaxy, quasar, and neutral gas distributions at redshifts out to z = 3.5to better understand dark matter, dark energy, the properties of neutrinos, and inflation.CitationMichael R. Blanton et al 2017 AJ 154 28. doi:10.3847/1538-3881/aa7567

Electric motor-transformer aggregate in hermetic objects of transport vehicles

NASA Astrophysics Data System (ADS)

Zabora, Igor

2017-10-01

The construction and features of operation for new electrical unit - electric motor-transformer aggregate (DTA) are considered. Induction motors are intended for operation in hermetic plants with extreme conditions surrounding gas, steam-to-gas and liquid environment at a high temperature (to several hundred of degrees). Main objective of spent researches is the substantiation of possibility reliable and effective electric power transform with electric machine means directly in hermetic objects with extreme conditions environment by means of new DTA. The principle and job analysis of new disk induction motors of block-module type are observed.

A Precision, Low-Cost GPS-Based Synchronization Scheme for Improved AM Reception.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Smith, Stephen Fulton; Moore, Anthony

2009-01-01

This paper describes a highly accurate carrier-frequency synchronization scheme for actively, automatically locking multiple, remotely located AM broadcast transmitters to a common frequency/timing reference source such as GPS. The extremely tight frequency lock (to ~1 part in 109 or better) permits the effective elimination of audible and even sub-audible beats between the local (desired) station s carrier signal and the distant stations carriers, usually received via skywave propagation during the evening and nighttime hours. These carrier-beat components cause annoying modulations of the desired station s audio at the receiver and concurrent distortion of the audio modulation from the distant station(s)more » and often cause listeners to tune out due to the poor reception quality. Significant reduction or elimination of the beats and related effects will greatly enlarge the effective (interference-limited) listening area of the desired station (from 4 to 10 times as indicated in our tests) and simultaneously reduce the corresponding interference of the local transmitter to the distant stations as well. In addition, AM stereo (CQUAM) reception will be particularly improved by minimizing the phase shifts induced by co-channel interfering signals; HD will also benefit via reduction in beats from analog signals. The automatic frequency-control hardware described is inexpensive ($1-2K), requires no periodic recalibration, has essentially zero long-term drift, and could employ alternate wide-area frequency references of suitable accuracy, including broadcasts from WWVB, LORAN-C, and equivalent sources. The basic configuration of the GPS-disciplined oscillator which solves this problem is extremely simple. The main oscillator is a conventional high-stability quartz-crystal type. To counter long-term drifts, the oscillator is slightly adjusted to track a high-precision source of standard frequency obtained from a specialized GPS receiver (or other source), usually at 10.000 MHz. This very stable local reference frequency is then used as a clock for a standard digitally implemented frequency synthesizer, which is programmed to generate the specific (AM broadcast) transmitter carrier frequency desired. The stability of the disciplining source, typically ~ 1 part in 109 to 1011, is thus transferred to the final AM transmitter carrier output frequency. Generally, an AM radio listener during the evening and nighttime hours, and to a lesser extent in the early morning, receives undesired skywave signals from several distant stations as well as the desired local (groundwave) signal. If all of these signals are within about 0.01-0.001 Hz of each other, any resulting carrier beats will be of such long periods that the beats will be effectively suppressed by the action of the receiver s AGC circuitry and thus be unnoticeable to the listener. Many modern, synthesizer-based transmitters can directly lock to the precision disciplined 10-MHz source, while older units usually require references at either1 e, 2 e, or 4 e the final frequency. In these latter cases, the existing transmitter crystal can usually be satisfactorily pulled via injection locking. The effectiveness of the synchronization concept to reduce interference effects was demonstrated in a laboratory test setup. Many hours of careful subjective listening were conducted, with the two interfering units both precisely on-frequency with the main unit (synchronous operation) and with the two interferers at various frequency offsets, from below 1 Hz to above 10 Hz.« less

Early Working Memory in Children Born With Extremely Low Birth Weight: Assessed by Object Permanence

PubMed Central

Lowe, Jean; MacLean, Peggy C.; Shaffer, Michele L.; Watterberg, Kristi

2011-01-01

Object permanence is considered the earliest method for assessing working memory. Factors affecting object permanence performance in a sample of two hundred and thirty-three 18- to 22-month olds born with extremely low birth weight were examined. It was hypothesized that object permanence would be directly related to emotional and attention regulation, that children with lower birth weight and higher illness severity would have more difficulty on the object permanence task, and that no ethnic/racial differences would be found, as this is considered a culturally unbiased task. Attainment of object permanence had a significant positive association with emotional and attention regulation, even after controlling the medical severity and socioeconomic factors. More girls than boys passed the object permanence items. There was no ethnic/racial difference on object permanence. Our findings indicate that object permanence may be a culturally fair way of assessing development, and emotional and attention regulation are potential avenues of intervention for such skill. PMID:19339284

Early working memory in children born with extremely low birth weight: assessed by object permanence.

PubMed

Lowe, Jean; MacLean, Peggy C; Shaffer, Michele L; Watterberg, Kristi

2009-04-01

Object permanence is considered the earliest method for assessing working memory. Factors affecting object permanence performance in a sample of two hundred and thirty-three 18- to 22-month olds born with extremely low birth weight were examined. It was hypothesized that object permanence would be directly related to emotional and attention regulation, that children with lower birth weight and higher illness severity would have more difficulty on the object permanence task, and that no ethnic/racial differences would be found, as this is considered a culturally unbiased task. Attainment of object permanence had a significant positive association with emotional and attention regulation, even after controlling the medical severity and socioeconomic factors. More girls than boys passed the object permanence items. There was no ethnic/racial difference on object permanence. Our findings indicate that object permanence may be a culturally fair way of assessing development, and emotional and attention regulation are potential avenues of intervention for such skill.

An empirical evaluation of genetic distance statistics using microsatellite data from bear (Ursidae) populations.

PubMed

Paetkau, D; Waits, L P; Clarkson, P L; Craighead, L; Strobeck, C

1997-12-01

A large microsatellite data set from three species of bear (Ursidae) was used to empirically test the performance of six genetic distance measures in resolving relationships at a variety of scales ranging from adjacent areas in a continuous distribution to species that diverged several million years ago. At the finest scale, while some distance measures performed extremely well, statistics developed specifically to accommodate the mutational processes of microsatellites performed relatively poorly, presumably because of the relatively higher variance of these statistics. At the other extreme, no statistic was able to resolve the close sister relationship of polar bears and brown bears from more distantly related pairs of species. This failure is most likely due to constraints on allele distributions at microsatellite loci. At intermediate scales, both within continuous distributions and in comparisons to insular populations of late Pleistocene origin, it was not possible to define the point where linearity was lost for each of the statistics, except that it is clearly lost after relatively short periods of independent evolution. All of the statistics were affected by the amount of genetic diversity within the populations being compared, significantly complicating the interpretation of genetic distance data.

An Empirical Evaluation of Genetic Distance Statistics Using Microsatellite Data from Bear (Ursidae) Populations

PubMed Central

Paetkau, D.; Waits, L. P.; Clarkson, P. L.; Craighead, L.; Strobeck, C.

1997-01-01

A large microsatellite data set from three species of bear (Ursidae) was used to empirically test the performance of six genetic distance measures in resolving relationships at a variety of scales ranging from adjacent areas in a continuous distribution to species that diverged several million years ago. At the finest scale, while some distance measures performed extremely well, statistics developed specifically to accommodate the mutational processes of microsatellites performed relatively poorly, presumably because of the relatively higher variance of these statistics. At the other extreme, no statistic was able to resolve the close sister relationship of polar bears and brown bears from more distantly related pairs of species. This failure is most likely due to constraints on allele distributions at microsatellite loci. At intermediate scales, both within continuous distributions and in comparisons to insular populations of late Pleistocene origin, it was not possible to define the point where linearity was lost for each of the statistics, except that it is clearly lost after relatively short periods of independent evolution. All of the statistics were affected by the amount of genetic diversity within the populations being compared, significantly complicating the interpretation of genetic distance data. PMID:9409849

Evaluation of Distant Education Programs with Regards to Various Shareholder Opinions

ERIC Educational Resources Information Center

Tonbuloglu, Betül; Gürol, Aysun

2016-01-01

The strong demand and rapid increase in the number of programs concerning distant education programs has put the quality problem of distant education services into the agenda. It is crucial to determine the strengths and weaknesses of distant education programs, the problems encountered by these programs and making the required improvements. The…

Myxofibrosarcoma of the sinus piriformis: case report and literature review.

PubMed

Qiubei, Zhu; Cheng, Lin; Yaping, Xu; Shunzhang, Lin; Jingping, Fan

2012-11-15

Myxofibrosarcoma is a common sarcoma in the extremities of older people, but is rare in the head and neck region. Here, we report the case of a 42-year-old male patient in whom myxofibrosarcoma generated from the sinus piriformis. Histopathologically, the tumor was characterized by spindle cellular proliferation with moderate cellular density in fibromyxoid stroma. Immunohistochemically, the tumor cells showed positive reactivity for vimentin, Ki-67, smooth muscle actin, and CD34, but negative staining for S-100. Based on these results, the tumor was diagnosed as a low-grade myxofibrosarcoma. Resection of the tumor was performed via a transcervical approach. The patient's postoperative clinical course was uneventful and no local recurrence or distant metastasis has been found so far. The pathology, clinical characteristics, and treatment of myxofibrosarcoma are also reviewed.

Supernovae and cosmology with future European facilities.

PubMed

Hook, I M

2013-06-13

Prospects for future supernova surveys are discussed, focusing on the European Space Agency's Euclid mission and the European Extremely Large Telescope (E-ELT), both expected to be in operation around the turn of the decade. Euclid is a 1.2 m space survey telescope that will operate at visible and near-infrared wavelengths, and has the potential to find and obtain multi-band lightcurves for thousands of distant supernovae. The E-ELT is a planned, general-purpose ground-based, 40-m-class optical-infrared telescope with adaptive optics built in, which will be capable of obtaining spectra of type Ia supernovae to redshifts of at least four. The contribution to supernova cosmology with these facilities will be discussed in the context of other future supernova programmes such as those proposed for DES, JWST, LSST and WFIRST.

Improved Heat-Stress Algorithm

NASA Technical Reports Server (NTRS)

Teets, Edward H., Jr.; Fehn, Steven

2007-01-01

NASA Dryden presents an improved and automated site-specific algorithm for heat-stress approximation using standard atmospheric measurements routinely obtained from the Edwards Air Force Base weather detachment. Heat stress, which is the net heat load a worker may be exposed to, is officially measured using a thermal-environment monitoring system to calculate the wet-bulb globe temperature (WBGT). This instrument uses three independent thermometers to measure wet-bulb, dry-bulb, and the black-globe temperatures. By using these improvements, a more realistic WBGT estimation value can now be produced. This is extremely useful for researchers and other employees who are working on outdoor projects that are distant from the areas that the Web system monitors. Most importantly, the improved WBGT estimations will make outdoor work sites safer by reducing the likelihood of heat stress.

Inflammatory breast metastases of ovarian cancer: a case report.

PubMed

Kayikçioğlu, F; Boran, N; Ayhan, A; Güler, N

2001-12-01

Metastasis to the breast from extramammary malignancies is rare. A 35-year-old woman presented with bilaterally inflammatory breast involvement, 2 years after the diagnosis of stage IIIC epithelial ovarian cancer. Neoplastic tissue was immunohistochemically positive using antibodies against OC125 and negative for gross cystic disease fluid protein-15 (BRST-2) and estrogen receptor in biopsy material in the breast. Combination chemotherapy consisting of paclitaxel, cisplatin, and anthracycline was started. She died 18 months after the breast metastasis. Ovarian carcinoma usually presents with signs and symptoms related to the tumor burden within the abdominal cavity. The finding of isolated, distant metastases such as breast involvement without intraabdominal disease is extremely rare. Determining the origin of the primary tumor is important in directing the actual therapy. (c)2001 Elsevier Science.

Luminous Blue Compact Galaxies: Probes of galaxy assembly

NASA Astrophysics Data System (ADS)

Newton, Cassidy Louann

The life cycles of galaxies over cosmic time is yet to be fully understood. How did galaxies evolve from their formative stages to the structures we observe today? This dissertation details the identification and analysis of a sample of Luminous Blue Compact Galaxies (LBCGs), a class of galaxy in the local (z < 0.05) universe exhibiting blue colors, high surface brightness, and high star formation rates. These systems appear to be very similar in their global properties to the early evolutionary phases of most galaxies, however their locality permits detailed investigation over a broad range of the electromagnetic spectrum in contrast to the smaller angular sizes and extreme faintness of distant galaxies. We use a combination of optical, ultraviolet, and infrared data to investigate a sample of LBCGs utilizing space and ground-based data.

Gravitational Waves From the Kerr/CFT Correspondence

NASA Astrophysics Data System (ADS)

Porfyriadis, Achilleas

Astronomical observation suggests the existence of near-extreme Kerr black holes in the sky. Properties of diffeomorphisms imply that dynamics of the near-horizon region of near-extreme Kerr are governed by an infinite-dimensional conformal symmetry. This symmetry may be exploited to analytically, rather than numerically, compute a variety of potentially observable processes. In this thesis we compute the gravitational radiation emitted by a small compact object that orbits in the near-horizon region and plunges into the horizon of a large rapidly rotating black hole. We study the holographically dual processes in the context of the Kerr/CFT correspondence and find our conformal field theory (CFT) computations in perfect agreement with the gravity results. We compute the radiation emitted by a particle on the innermost stable circular orbit (ISCO) of a rapidly spinning black hole. We confirm previous estimates of the overall scaling of the power radiated, but show that there are also small oscillations all the way to extremality. Furthermore, we reveal an intricate mode-by-mode structure in the flux to infinity, with only certain modes having the dominant scaling. The scaling of each mode is controlled by its conformal weight. Massive objects in adiabatic quasi-circular inspiral towards a near-extreme Kerr black hole quickly plunge into the horizon after passing the ISCO. The post-ISCO plunge trajectory is shown to be related by a conformal map to a circular orbit. Conformal symmetry of the near-horizon region is then used to compute analytically the gravitational radiation produced during the plunge phase. Most extreme-mass-ratio-inspirals of small compact objects into supermassive black holes end with a fast plunge from an eccentric last stable orbit. We use conformal transformations to analytically solve for the radiation emitted from various fast plunges into extreme and near-extreme Kerr black holes.

Trajectories for the Sakigake extended-mission phase

NASA Technical Reports Server (NTRS)

Farquhar, R.; Dunham, D.; Hsu, S.; Uesugi, K.; Kawaguchi, J.

1988-01-01

The trajectory profile that will be used by Japan's Sakigake spacecraft to accomplish its extended-mission objectives is described. Currently, Sakigake is following a heliocentric trajectory that will return to the earth's vicinity in January 1992. Four earth gravity-assist maneuvers are planned to redirect Sakigake to an encounter with Comet Honda-Mrkos-Pajdusakova (HMP) in February 1996. While carrying out the earth-swingby maneuvers, the spacecraft will make several passes through previously unexplored regions of the distant geomagnetic tail.

Research Technology

NASA Image and Video Library

1999-10-21

Travel to distant stars is a long-range goal of Marshall Space Flight Center's Advanced Concept Group. One of the many propulsion systems currently being studied is fusion power. The objective of this and many other alternative propulsion systems is to reduce the costs of space access and to reduce the travel time for planetary missions. One of the major factors is providing an alternate engery source for these missions. Pictured is an artist's concept of future interplanetary space flight using fusion power.

Active Tobacco Smoking and Distant Metastasis in Patients With Oropharyngeal Cancer

DOE Office of Scientific and Technical Information (OSTI.GOV)

McBride, Sean M.; Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; Ali, Nawal N.

Purpose: Distant metastasis is the site of first relapse in approximately one-third of patients with locally advanced oropharyngeal carcinoma, irrespective of human papillomavirus status. Yet the risk factors associated with distant metastasis are not well characterized. We sought to characterize the relationship between smoking status and distant metastasis. Methods and Materials: We evaluated the association between tobacco smoking status and distant metastasis in a retrospective cohort study of 132 patients who underwent definitive radiation therapy and chemotherapy for Stage III-IVA/B oropharyngeal cancer. Information on tobacco smoking was prospectively collected by patient questionnaires and physician notes at the time of diagnosis.more » Thirty-three percent of the patients were nonsmokers, 51% were former smokers, 16% were active smokers. The cumulative lifetime tobacco smoking in pack-years was 20 (range, 0-150). Results: With a median follow-up time of 52 months, the overall rate of distant metastasis at 4 years was 8%. Distant metastasis was the most common first site of relapse, occurring in 56% of the patients with recurrences. Active smokers had higher rates of distant metastasis than non-active smokers (including never- and former smokers; 31% vs. 4%, p < 0.001) and former smokers (31% vs. 3%, p < 0.001). There was no statistically significant difference in the risk of distant metastasis for patients with lifetime cumulative pack-years >20 and {<=}20 (10% vs. 4%, p = 0.19). In univariate analysis, active smoking (p = 0.0004) and N category (p = 0.009) were predictive of increased risk of distant metastasis. In multivariate analysis, active smoking was the most significant predictive factor for increased risk of distant metastasis (hazard ratio, 12.7, p < 0.0001). Conclusions: This study identified a strong association between active smoking and distant metastasis in patients with oropharyngeal cancer.« less

Negative and positive life events are associated with small but lasting change in neuroticism.

PubMed

Jeronimus, B F; Ormel, J; Aleman, A; Penninx, B W J H; Riese, H

2013-11-01

High neuroticism is prospectively associated with psychopathology and physical health. However, within-subject changes in neuroticism due to life experiences (LEs) or state effects of current psychopathology are largely unexplored. In this 2-year follow-up study, four hypotheses were tested: (1) positive LEs (PLEs) decrease and negative LEs (NLEs) increase neuroticism; (2) LE-driven change in neuroticism is partly long-lasting; and (3) partly independent of LE-driven changes in anxiety/depression; and (4) childhood adversity (before age 16 years) moderates the influence of NLEs/PLEs on neuroticism scores in adult life. Data came from the Netherlands Study of Depression and Anxiety [NESDA, n = 2981, mean age 41.99 years (s.d. = 13.08), 66.6% women]. At follow-up (T₂) we assessed PLEs/NLEs with the List of Threatening Experiences (LTE) over the prior 24 months and categorized them over recent and distant PLE/NLE measures (1-3 and 4-24 months prior to T₂ respectively) to distinguish distant NLE/PLE-driven change in trait neuroticism (using the Dutch version of the Neuroticism-Extroversion-Openness Five Factor Inventory, NEO-FFI) from state deviations due to changes in symptoms of depression (self-rated version of the 30-item Inventory of Depressive Symptomatology, IDS-SR30) and anxiety (Beck Anxiety Inventory, BAI). Distant NLEs were associated with higher and distant PLEs with lower neuroticism scores. The effects of distant LEs were weak but long-lasting, especially for distant PLEs. Distant NLE-driven change in neuroticism was associated with change in symptoms of anxiety/depression whereas the effect of distant PLEs on neuroticism was independent of any such changes. Childhood adversity weakened the impact of distant NLEs but enhanced the impact of distant PLEs on neuroticism. Distant PLEs are associated with small but long-lasting decreases in neuroticism regardless of changes in symptom levels of anxiety/depression. Long-lasting increases in neuroticism associated with distant NLEs are mediated by anxiety/depression.

Centaurs and Activity Beyond the Water Sublimation Zone

NASA Astrophysics Data System (ADS)

Jewitt, David

2017-08-01

Centaurs are icy objects in dynamical transition between the Kuiper belt, where they originate, and the Jupiter family comets. Water ice in inward drifting Centaurs should begin to sublimate measurably when their perihelion reaches the orbit of Jupiter (5 AU). Instead, a fraction of Centaurs become active (have a cometary appearance) even with perihelia at Saturn (10 AU). Of the many suggestions made for the origin of this distant activity, the current favorite and the one with the largest impact on cometary science is the crystallization of amorphous water ice. Amorphous ice is an excellent carrier of supervolatiles (e.g. CO, N2) which are released upon the exothermic transition to crystalline ice. If Centaur ice is amorphous, then so must be Kuiper belt ice, setting strong constraints on the internal temperature vs. time history of the Kuiper belt objects. If the crystallization hypothesis is correct, we should never find an active Centaur with a perihelion substantially beyond the so-called crystallization line at about 12 AU (because temperatures there are too low to trigger crystallization). We propose a simple search for distant activity in Centaurs with perihelia 15 to 20 AU, in which crystallization cannot occur, in order to challenge the crystallization hypothesis. The search is made possible by the tight and stable point spread function and sensitivity to near-nucleus coma of HST.

Observational Constraints on the Orbit and Location of Planet Nine in the Outer Solar System

NASA Astrophysics Data System (ADS)

Brown, Michael E.; Batygin, Konstantin

2016-06-01

We use an extensive suite of numerical simulations to constrain the mass and orbit of Planet Nine, the recently proposed perturber in a distant eccentric orbit in the outer solar system. We compare our simulations to the observed population of aligned eccentric high semimajor axis Kuiper belt objects (KBOs) and determine which simulation parameters are statistically compatible with the observations. We find that only a narrow range of orbital elements can reproduce the observations. In particular, the combination of semimajor axis, eccentricity, and mass of Planet Nine strongly dictates the semimajor axis range of the orbital confinement of the distant eccentric KBOs. Allowed orbits, which confine KBOs with semimajor axis beyond 380 au, have perihelia roughly between 150 and 350 au, semimajor axes between 380 and 980 au, and masses between 5 and 20 Earth masses. Orbitally confined objects also generally have orbital planes similar to that of the planet, suggesting that the planet is inclined approximately 30°to the ecliptic. We compare the allowed orbital positions and estimated brightness of Planet Nine to previous and ongoing surveys which would be sensitive to the planet’s detection and use these surveys to rule out approximately two-thirds of the planet’s orbit. Planet Nine is likely near aphelion with an approximate brightness of 22< V< 25. At opposition, its motion, mainly due to parallax, can easily be detected within 24 hours.

Minimally invasive surgery using intraoperative electron-beam radiotherapy for the treatment of soft tissue sarcoma of the extremities with tendon involvement.

PubMed

Matsumine, Akihiko; Tsujii, Masaya; Nakamura, Tomoki; Asanuma, Kunihiro; Matsubara, Takao; Kakimoto, Takuya; Yada, Yuki; Takada, Akinori; Ii, Noriko; Nomoto, Yoshihito; Sudo, Akihiro

2016-08-12

When a soft tissue sarcoma (STS) is located at the distal part of an extremity and involves the tendon, a wide excision usually causes severe functional disability. We therefore developed a minimally invasive surgical technique using intraoperative electron-beam radiotherapy (IOERT) to reduce the incidence of post-operative functional disability in patients with peri-/intra-tendinous STS. We assessed the clinical outcomes of the novel minimally invasive surgery. The study population included five patients who received treatment for distal extremity STSs. After elevating the tumor mass, including the tendon and nerve from the tumor bed with a wide margin, a lead board was inserted beneath the tumor mass to shield the normal tissue. IOERT (25-50 Gy) was then applied, and the tumor excised with care taken to maintain the continuity of the tendon. In a desmoid patient, local recurrence was observed outside the irradiated field. No cases of neuropathy or bone necrosis were observed. The mean limb function score was excellent in all patients. None of the high-grade sarcoma patients had local recurrence or distant metastasis. Although the current study is only a pilot study with a small number of patients, it shows that this minimally invasive procedure has the potential to become a standard treatment option for selected patients. H17-250 (registered 2 November 2005) and H25-250 (modified from H17-250, registered 5 December 2013).

The Anterior Interosseus Artery Perforator Flap: Anatomical Dissections and Clinical Study

PubMed Central

Panse, Nikhil S; Joshi, Sheetal B; Sahasrabudhe, Parag B; Bahetee, B; Gurude, Pradnya; Chandanwale, Ajay

2017-01-01

BACKGROUND Reconstruction of upper extremity deformities continues to be a challenge to the reconstructive surgeon. Various loco regional, distant and free flaps are available for reconstruction. However, each has its own set of advantages and disadvantages. Of the commonly performed local flaps, radial artery forearm flap, and the posterior interosseus artery flap stand out prominently. Recently, perforator propeller flaps have been used for resurfacing the upper extremity. The anterior interosseus artery perforator flap is an uncommonly used and described flap. METHODS This study was divided into anatomical study and clinical application in a IV level of evidence. In the anatomical study, five upper extremities were studied. Clinically, 12 patients underwent reconstruction using the anterior interosseus artery perforator flap. Flaps were performed by a single surgeon. A retrospective review of these cases from November 2008 to May 2014 is presented. RESULTS The anterior interosseus artery perforator was identified in four out of five cadaver limbs. The septocutaneous perforator was in the fifth extensor compartment around 4 cm proximal to the wrist joint. Of the twelve flaps, there was complete necrosis in one flap, and partial necrosis in one flap. The patient with complete necrosis underwent skin grafting at a later date. The wound healed secondarily in case of partial flap necrosis. CONCLUSION Anterior interosseus artery perforator flap must be considered as an important reconstructive option in the armamentarium of the plastic surgeon, while managing hand and wrist defects. PMID:28713704

Improved forecasts of winter weather extremes over midlatitudes with extra Arctic observations

NASA Astrophysics Data System (ADS)

Sato, Kazutoshi; Inoue, Jun; Yamazaki, Akira; Kim, Joo-Hong; Maturilli, Marion; Dethloff, Klaus; Hudson, Stephen R.; Granskog, Mats A.

2017-02-01

Recent cold winter extremes over Eurasia and North America have been considered to be a consequence of a warming Arctic. More accurate weather forecasts are required to reduce human and socioeconomic damages associated with severe winters. However, the sparse observing network over the Arctic brings errors in initializing a weather prediction model, which might impact accuracy of prediction results at midlatitudes. Here we show that additional Arctic radiosonde observations from the Norwegian young sea ICE expedition (N-ICE2015) drifting ice camps and existing land stations during winter improved forecast skill and reduced uncertainties of weather extremes at midlatitudes of the Northern Hemisphere. For two winter storms over East Asia and North America in February 2015, ensemble forecast experiments were performed with initial conditions taken from an ensemble atmospheric reanalysis in which the observation data were assimilated. The observations reduced errors in initial conditions in the upper troposphere over the Arctic region, yielding more precise prediction of the locations and strengths of upper troughs and surface synoptic disturbances. Errors and uncertainties of predicted upper troughs at midlatitudes would be brought with upper level high potential vorticity (PV) intruding southward from the observed Arctic region. This is because the PV contained a "signal" of the additional Arctic observations as it moved along an isentropic surface. This suggests that a coordinated sustainable Arctic observing network would be effective not only for regional weather services but also for reducing weather risks in locations distant from the Arctic.

KSC-99pp1059

NASA Image and Video Library

1999-08-19

STS-93 Commander Eileen M. Collins signs autographs after a mission presentation for KSC employees. The five-day mission primarily released the Chandra X-ray Observatory, allowing scientists from around the world to study some of the most distant, powerful and dynamic objects in the universe. Chandra is expected to provide unique and crucial information on the nature of objects ranging from comets in our solar system to quasars at the edge of the observable universe. Since X-rays are absorbed by the Earth's atmosphere, space-based observatories are necessary to study these phenomena and allow scientists to analyze some of the greatest mysteries of the universe. STS-93 was also the first mission to have a woman serving as Shuttle commander

37 CFR 256.2 - Royalty fee for compulsory license for secondary transmission by cable systems.

Code of Federal Regulations, 2013 CFR

2013-07-01

... receipts for the first distant signal equivalent; (3) .668 of 1 per centum of such gross receipts for each of the second, third and fourth distant signal equivalents; and (4) .314 of 1 per centum of such gross receipts for the fifth distant signal equivalent and each additional distant signal equivalent...

37 CFR 256.2 - Royalty fee for compulsory license for secondary transmission by cable systems.

Code of Federal Regulations, 2012 CFR

2012-07-01

... receipts for the first distant signal equivalent; (3) .668 of 1 per centum of such gross receipts for each of the second, third and fourth distant signal equivalents; and (4) .314 of 1 per centum of such gross receipts for the fifth distant signal equivalent and each additional distant signal equivalent...

37 CFR 256.2 - Royalty fee for compulsory license for secondary transmission by cable systems.

Code of Federal Regulations, 2011 CFR

2011-07-01

... receipts for the first distant signal equivalent; (3) .668 of 1 per centum of such gross receipts for each of the second, third and fourth distant signal equivalents; and (4) .314 of 1 per centum of such gross receipts for the fifth distant signal equivalent and each additional distant signal equivalent...

37 CFR 256.2 - Royalty fee for compulsory license for secondary transmission by cable systems.

Code of Federal Regulations, 2014 CFR

2014-07-01

... gross receipts for the first distant signal equivalent; (3) .668 of 1 per centum of such gross receipts for each of the second, third and fourth distant signal equivalents; and (4) .314 of 1 per centum of such gross receipts for the fifth distant signal equivalent and each additional distant signal...

37 CFR 256.2 - Royalty fee for compulsory license for secondary transmission by cable systems.

Code of Federal Regulations, 2010 CFR

2010-07-01

... receipts for the first distant signal equivalent; (3) .668 of 1 per centum of such gross receipts for each of the second, third and fourth distant signal equivalents; and (4) .314 of 1 per centum of such gross receipts for the fifth distant signal equivalent and each additional distant signal equivalent...

Adjusting skewness and maximum 0.5 hour intensity in CLIGEN to improve extreme event and sub-daily intensity generation for assessing climate change impacts

USDA-ARS?s Scientific Manuscript database

Both measured data and GCM/RCM projections show an general increasing trend in extreme rainfall events as temperature rises in US. Proper simulation of extreme events is particularly important for assessing climate change impacts on soil erosion and hydrology. The objective of this paper is to fin...

Debriefing to Learn from Extreme Events: The Case of Utøya

ERIC Educational Resources Information Center

Firing, Kristian; Moen, Alexander; Skarsvåg, Kåre Inge

2015-01-01

The objective of this study was to discover potential ways to enhance debriefing so that more can be learned from the experience of extreme events. In order to reach this aim, we explored how personnel in the Explosive Ordnance Disposal team from the Norwegian Armed Forces experienced debriefing after an extreme event. That event was a terror…

Climate change impacts on tropical cyclones and extreme sea levels in the South Pacific — A regional assessment

NASA Astrophysics Data System (ADS)

Walsh, Kevin J. E.; McInnes, Kathleen L.; McBride, John L.

2012-01-01

This paper reviews the current understanding of the effect of climate change on extreme sea levels in the South Pacific region. This region contains many locations that are vulnerable to extreme sea levels in the current climate, and projections indicate that this vulnerability will increase in the future. The recent publication of authoritative statements on the relationship between global warming and global sea level rise, tropical cyclones and the El Niño-Southern Oscillation phenomenon has motivated this review. Confident predictions of global mean sea level rise are modified by regional differences in the steric (density-related) component of sea level rise and changing gravitational interactions between the ocean and the ice sheets which affect the regional distribution of the eustatic (mass-related) contribution to sea level rise. The most extreme sea levels in this region are generated by tropical cyclones. The intensity of the strongest tropical cyclones is likely to increase, but many climate models project a substantial decrease in tropical cyclone numbers in this region, which may lead to an overall decrease in the total number of intense tropical cyclones. This projection, however, needs to be better quantified using improved high-resolution climate model simulations of tropical cyclones. Future changes in ENSO may lead to large regional variations in tropical cyclone incidence and sea level rise, but these impacts are also not well constrained. While storm surges from tropical cyclones give the largest sea level extremes in the parts of this region where they occur, other more frequent high sea level events can arise from swell generated by distant storms. Changes in wave climate are projected for the tropical Pacific due to anthropogenically-forced changes in atmospheric circulation. Future changes in sea level extremes will be caused by a combination of changes in mean sea level, regional sea level trends, tropical cyclone incidence and wave climate. Recommendations are given for research to increase understanding of the response of these factors to climate change. Implications of the results for adaptation research are also discussed.

A SWIRE Picture is Worth Billions of Years

NASA Technical Reports Server (NTRS)

2005-01-01

[figure removed for brevity, see original site] Figure 1: SWIRE View of Distant Galaxies [figure removed for brevity, see original site] [figure removed for brevity, see original site] [figure removed for brevity, see original site] Figure 2Figure 3 Figure 4

These spectacular images, taken by the Spitzer Wide-area Infrared Extragalactic (SWIRE) Legacy project, encapsulate one of the primary objectives of the Spitzer mission: to connect the evolution of galaxies from the distant, or early, universe to the nearby, or present day, universe.

The Tadpole galaxy (main image) is the result of a recent galactic interaction in the local universe. Although these galactic mergers are rare in the universe's recent history, astronomers believe that they were much more common in the early universe. Thus, SWIRE team members will use this detailed image of the Tadpole galaxy to help understand the nature of the 'faint red-orange specks' of the early universe.

The larger picture (figure 2) depicts one-sixteenth of the SWIRE survey field called ELAIS-N1. In this image, the bright blue sources are hot stars in our own Milky Way, which range anywhere from 3 to 60 times the mass of our Sun. The fainter green spots are cooler stars and galaxies beyond the Milky Way whose light is dominated by older stellar populations. The red dots are dusty galaxies that are undergoing intense star formation. The faintest specks of red-orange are galaxies billions of light-years away in the distant universe.

Figure 3 features an unusual ring-like galaxy called CGCG 275-022. The red spiral arms indicate that this galaxy is very dusty and perhaps undergoing intense star formation. The star-forming activity could have been initiated by a near head-on collision with another galaxy.

The most distant galaxies that SWIRE is able to detect are revealed in a zoom of deep space (figure 4). The colors in this feature represent the same objects as those in the larger field image of ELAIS-N1.

The observed SWIRE fields were chosen on the basis of being 'empty' or as free as possible from the obscuring dust, gas, and stars of our own Milky Way. Because Earth is located within the Milky Way galaxy, there is always a screen of Milky Way objects blocking our view of the rest of the universe. In some places, our view of the larger universe is less obscured than others and for the most part is considered 'empty.' These are prime observing spots for astronomers interested in studying objects beyond the Milky Way. ELAIS-N1 is only one of six SWIRE survey fields. The full survey covers 49 square degrees of the sky, equivalent to the area covered by about 250 full moons.

The SWIRE images are 3-channel false-color composites, where blue represents visible green light (light that would appear to be blue/green to the human eye), green captures infrared light of 3.6 microns, and red represents infrared emissions of 8 microns. The infrared data are from Spitzer's infrared array camera and the visible-light data are from the Isaac Newton Telescope, Spain.

Coexpression of α6β4 Integrin and Guanine Nucleotide Exchange Factor Net1 Identifies Node-Positive Breast Cancer Patients at High Risk for Distant Metastasis

PubMed Central

Gilcrease, Michael Z.; Kilpatrick, Shannan K.; Woodward, Wendy A.; Zhou, Xiao; Nicolas, Marlo M.; Corley, Lynda J.; Fuller, Gregory N.; Tucker, Susan L.; Diaz, Leslie K.; Buchholz, Thomas A.; Frost, Jeffrey A.

2009-01-01

Preclinical data indicate that α6β4 integrin signaling through Ras homolog gene family, member A, plays an important role in tumor cell motility. The objective of this study was to determine whether the combined expression of α6β4 integrin and neuroepithelioma transforming gene 1 (Net1), a guanine nucleotide exchange factor specific for Ras homolog gene family member A, is associated with adverse clinical outcome in breast cancer patients. Immunohistochemical expression of each protein was evaluated in a tumor tissue microarray prepared from the primary tumors of 94 node-positive patients with invasive breast carcinoma treated with total mastectomy and doxorubicin-based chemotherapy without radiation with a median follow-up of 12.5 years. Associations between staining results and multiple clinicopathologic variables were investigated. Although there was no significant association between α6β4 integrin or Net1 expression and clinical outcome when each marker was considered individually, coexpression of α6β4 and Net1 was associated with decreased distant metastasis–free survival (P = 0.030). In the subset of patients with hormone receptor–positive tumors, coexpression of α6β4 and Net1 was associated with a decrease in distant metastasis–free and overall survival (P < 0.001 and P = 0.006, respectively). Although an association between human epidermal growth factor receptor 2 expression and coexpression of α6β4 and Net1 (P = 0.008) was observed, coexpression of α6β4 and Net1 (hazard ratio, 1.63; P = 0.02) and lymphovascular invasion (hazard ratio, 2.35; P = 0.02) were the only factors independently associated with the development of distant metastasis in multivariate analysis. These findings suggest that coexpression of α6β4 integrin and Net1 could be a useful biomarker for aggressive disease in node-positive breast cancer patients. PMID:19124484

Effects of clinical supervision on resident learning and patient care during simulated ICU scenarios.

PubMed

Piquette, Dominique; Tarshis, Jordan; Regehr, Glenn; Fowler, Robert A; Pinto, Ruxandra; LeBlanc, Vicki R

2013-12-01

Closer supervision of residents' clinical activities has been promoted to improve patient safety, but may additionally affect resident participation in patient care and learning. The objective of this study was to determine the effects of closer supervision on patient care, resident participation, and the development of resident ability to care independently for critically ill patients during simulated scenarios. This quantitative study represents a component of a larger mixed-methods study. Residents were randomized to one of three levels of supervision, defined by the physical proximity of the supervisor (distant, immediately available, and direct). Each resident completed a simulation scenario under the supervision of a critical care fellow, immediately followed by a modified scenario of similar content without supervision. The simulation center of a tertiary, university-affiliated academic center in a large urban city. Fifty-three residents completing a critical care rotation and 24 critical care fellows were recruited between April 2009 and June 2010. None. During the supervised scenarios, lower team performance checklist scores were obtained for distant supervision compared with immediately available and direct supervision (mean [SD], direct: 72% [12%] vs immediately available: 77% [10%] vs distant: 61% [11%]; p = 0.0013). The percentage of checklist items completed by the residents themselves was significantly lower during direct supervision (median [interquartile range], direct: 40% [21%] vs immediately available: 58% [16%] vs distant: 55% [11%]; p = 0.005). During unsupervised scenarios, no significant differences were found on the outcome measures. Care delivered in the presence of senior supervising physicians was more comprehensive than care delivered without access to a bedside supervisor, but was associated with lower resident participation. However, subsequent resident performance during unsupervised scenarios was not adversely affected. Direct supervision of residents leads to improved care process and does not diminish the subsequent ability of residents to function independently.

High molecular gas fractions in normal massive star-forming galaxies in the young Universe.

PubMed

Tacconi, L J; Genzel, R; Neri, R; Cox, P; Cooper, M C; Shapiro, K; Bolatto, A; Bouché, N; Bournaud, F; Burkert, A; Combes, F; Comerford, J; Davis, M; Schreiber, N M Förster; Garcia-Burillo, S; Gracia-Carpio, J; Lutz, D; Naab, T; Omont, A; Shapley, A; Sternberg, A; Weiner, B

2010-02-11

Stars form from cold molecular interstellar gas. As this is relatively rare in the local Universe, galaxies like the Milky Way form only a few new stars per year. Typical massive galaxies in the distant Universe formed stars an order of magnitude more rapidly. Unless star formation was significantly more efficient, this difference suggests that young galaxies were much more molecular-gas rich. Molecular gas observations in the distant Universe have so far largely been restricted to very luminous, rare objects, including mergers and quasars, and accordingly we do not yet have a clear idea about the gas content of more normal (albeit massive) galaxies. Here we report the results of a survey of molecular gas in samples of typical massive-star-forming galaxies at mean redshifts of about 1.2 and 2.3, when the Universe was respectively 40% and 24% of its current age. Our measurements reveal that distant star forming galaxies were indeed gas rich, and that the star formation efficiency is not strongly dependent on cosmic epoch. The average fraction of cold gas relative to total galaxy baryonic mass at z = 2.3 and z = 1.2 is respectively about 44% and 34%, three to ten times higher than in today's massive spiral galaxies. The slow decrease between z approximately 2 and z approximately 1 probably requires a mechanism of semi-continuous replenishment of fresh gas to the young galaxies.

Treatment of Vascular Soft Tissue Sarcomas With Razoxane, Vindesine, and Radiation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rhomberg, Walter; Wink, Anna; Pokrajac, Boris

2009-05-01

Purpose: In previous studies, razoxane and vindesine together with radiotherapy was proved to be effective in soft tissue sarcomas (STS). Because razoxane leads to a redifferentiation of pathological tumor blood vessels, it was of particular interest to study the influence of this drug combination in vascular soft tissue sarcomas. Methods and Materials: This open multicenter Phase II study was performed by the Austrian Society of Radiooncology. Among 13 evaluable patients (10 angiosarcomas and 3 hemangio-pericytomas), 9 had unresectable measurable disease, 3 showed microscopic residuals, and 1 had a resection with clear margins. They received a basic treatment with razoxane andmore » vindesine supported by radiation therapy. Outcome measures were objective response rates, survival time, and the incidence of distant metastases. Results: In nine patients with measurable vascular soft tissue sarcomas (eight angiosarcomas and one hemangiopericytoma), 6 complete remissions, 2 partial remissions, and 1 minor remission were achieved, corresponding to a major response rate of 89%. A maintenance therapy with razoxane and vindesine of 1 year or longer led to a suppression of distant metastases. The median survival time from the start of the treatment is 23+ months (range, 3-120+) for 12 patients with macroscopic and microscopic residual disease. The progression-free survival at 6 months was 75%. The combined treatment was associated with a low general toxicity, but attention must be given to increased normal tissue reactions. Conclusions: This trimodal treatment leads to excellent response rates, and it suppresses distant metastases when given as maintenance therapy.« less

Stellar Populations and Physical Conditions at 100 pc Resolution in a Lensed Galaxy at z 4

NASA Astrophysics Data System (ADS)

Berg, Danielle

2015-10-01

Large surveys of star-forming galaxies at high redshift (z > 1.5) have provided us with a broad understanding of how galaxies assemble and evolve, but the spatial and spectral limitations inherent in observing faint, distant objects mean that many of the physical processes regulating this dynamic evolution are poorly constrained. Much of our most detailed knowledge of the physical conditions in distant galaxies comes from careful studies of gravitationally lensed sources, few of which are at z>3.5. FOR J0332-3557 is a gravitationally lensed galaxy at z 4 for which we and other groups have obtained a total of 37.3 hours of VLT spectroscopy. The rest-frame UV spectrum is notable for its unusual combination of both strong emission lines in the rest-frame UV and strong Lya and interstellar absorption, and for the unusual spatial variation seen in the nebular emission lines, which are less extended than the underlying stellar continuum. We propose high spatial resolution imaging of FOR J0332-3557 with four broadband filters on WFC3, taking advantage of both the HST resolution and the lensing magnification to study star formation and extinction on 100 pc scales. Because the interpretation of our unusual rest-frame UV and optical spectra requires an accurate reddening estimate, combining these observations with ground-based spectroscopy will give the most complete picture to date of chemical evolution in a distant galaxy.

Study of Pure Proteins, Nucleic Acids and Their Complexes from Halobacteria of the Dead Sea: RNA Polymerase-DNA Interaction.

DTIC Science & Technology

1987-09-21

objectives of our program are to isolate and characterize a fully active DNA dependent RNA polymerase from the extremely halophilic archaebacteria of the genus...operons in II. Marismortui. The halobacteriaceae are extreme halophiles . They require 3.5 M NaCI for optimal growth an(l no growth is observed below 2...was difficutlt to perform due to the extreme genetic instability in this strain (6). In contrast, the genoine of the extreme halophilic and prototrophic

GALAXIES IN THE YOUNG UNIVERSE [left

NASA Technical Reports Server (NTRS)

2002-01-01

This image of a small region of the constellation Sculptor, taken with a ground-based photographic sky survey camera, illustrates the extremely small angular size of a distant galaxy cluster in the night sky. Though this picture encompasses a piece of the sky about the width of the bowl of the Big Dipper, the cluster is so far away it fills a sky area only 1/10th the diameter of the Full Moon. The cluster members are not visible because they are so much fainter than foreground stars. [center] A NASA Hubble Space Telescope (HST) image of the farthest cluster of galaxies in the universe, located at a distance of 12 billion light-years. Because the light from these remote galaxies has taken 12 billion years to reach us, this image is a remarkable glimpse of the primeval universe, at it looked about two billion years after the Big Bang. The cluster contains 14 galaxies, the other objects are largely foreground galaxies. The galaxy cluster lies in front of quasar Q0000-263 in the constellation Sculptor. Presumably the brilliant core of an active galaxy, the quasar provides a beacon for searching for primordial galaxy clusters. The image is the full field view of the Wide Field and Planetary Camera-2, taken on September 6, 1994. The 4.7-hour exposure reveals objects down to 28.5 magnitude. [right] This enlargement shows one of the farthest normal galaxies yet detected, (blob at center right) at a distance of 12 billion light-years (redshift of z=3.330). The galaxy lies 300 million light-years in front of the quasar Q0000-263 (z=4.11, large white blob and spike on left side of frame) and was detected because it absorbs some light from the quasar. The galaxy's spectrum reveals that vigorous star formation is taking place. Credit: Duccio Macchetto (ESA/STScI), Mauro Giavalisco (STScI), and NASA

Algorithm to find distant repeats in a single protein sequence

PubMed Central

Banerjee, Nirjhar; Sarani, Rangarajan; Ranjani, Chellamuthu Vasuki; Sowmiya, Govindaraj; Michael, Daliah; Balakrishnan, Narayanasamy; Sekar, Kanagaraj

2008-01-01

Distant repeats in protein sequence play an important role in various aspects of protein analysis. A keen analysis of the distant repeats would enable to establish a firm relation of the repeats with respect to their function and three-dimensional structure during the evolutionary process. Further, it enlightens the diversity of duplication during the evolution. To this end, an algorithm has been developed to find all distant repeats in a protein sequence. The scores from Point Accepted Mutation (PAM) matrix has been deployed for the identification of amino acid substitutions while detecting the distant repeats. Due to the biological importance of distant repeats, the proposed algorithm will be of importance to structural biologists, molecular biologists, biochemists and researchers involved in phylogenetic and evolutionary studies. PMID:19052663

Clearing the Cosmic Fog - The Most Distant Galaxy Ever Measured

NASA Astrophysics Data System (ADS)

2010-10-01

A European team of astronomers using ESO's Very Large Telescope (VLT) has measured the distance to the most remote galaxy so far. By carefully analysing the very faint glow of the galaxy they have found that they are seeing it when the Universe was only about 600 million years old (a redshift of 8.6). These are the first confirmed observations of a galaxy whose light is clearing the opaque hydrogen fog that filled the cosmos at this early time. The results were presented at an online press conference with the scientists on 19 October 2010, and will appear in the 21 October issue of the journal Nature. "Using the ESO Very Large Telescope we have confirmed that a galaxy spotted earlier using Hubble is the most remote object identified so far in the Universe" [1], says Matt Lehnert (Observatoire de Paris) who is lead author of the paper reporting the results. "The power of the VLT and its SINFONI spectrograph allows us to actually measure the distance to this very faint galaxy and we find that we are seeing it when the Universe was less than 600 million years old." Studying these first galaxies is extremely difficult. By the time that their initially brilliant light gets to Earth they appear very faint and small. Furthermore, this dim light falls mostly in the infrared part of the spectrum because its wavelength has been stretched by the expansion of the Universe - an effect known as redshift. To make matters worse, at this early time, less than a billion years after the Big Bang, the Universe was not fully transparent and much of it was filled with a hydrogen fog that absorbed the fierce ultraviolet light from young galaxies. The period when the fog was still being cleared by this ultraviolet light is known as the era of reionisation [2]. Despite these challenges the new Wide Field Camera 3 on the NASA/ESA Hubble Space Telescope discovered several robust candidate objects in 2009 [3] that were thought to be galaxies shining in the era of reionisation. Confirming the distances to such faint and remote objects is an enormous challenge and can only reliably be done using spectroscopy from very large ground-based telescopes [4], by measuring the redshift of the galaxy's light. Matt Lehnert takes up the story: "After the announcement of the candidate galaxies from Hubble we did a quick calculation and were excited to find that the immense light collecting power of the VLT, when combined with the sensitivity of the infrared spectroscopic instrument, SINFONI, and a very long exposure time might just allow us to detect the extremely faint glow from one of these remote galaxies and to measure its distance." On special request to ESO's Director General they obtained telescope time on the VLT and observed a candidate galaxy called UDFy-38135539 [5] for 16 hours. After two months of very careful analysis and testing of their results, the team found that they had clearly detected the very faint glow from hydrogen at a redshift of 8.6, which makes this galaxy the most distant object ever confirmed by spectroscopy. A redshift of 8.6 corresponds to a galaxy seen just 600 million years after the Big Bang. Co-author Nicole Nesvadba (Institut d'Astrophysique Spatiale) sums up this work, "Measuring the redshift of the most distant galaxy so far is very exciting in itself, but the astrophysical implications of this detection are even more important. This is the first time we know for sure that we are looking at one of the galaxies that cleared out the fog which had filled the very early Universe." One of the surprising things about this discovery is that the glow from UDFy-38135539 seems not to be strong enough on its own to clear out the hydrogen fog. "There must be other galaxies, probably fainter and less massive nearby companions of UDFy-38135539, which also helped make the space around the galaxy transparent. Without this additional help the light from the galaxy, no matter how brilliant, would have been trapped in the surrounding hydrogen fog and we would not have been able to detect it", explains co-author Mark Swinbank (Durham University). Co-author Jean-Gabriel Cuby (Laboratoire d'Astrophysique de Marseille) remarks: "Studying the era of reionisation and galaxy formation is pushing the capability of current telescopes and instruments to the limit, but this is just the type of science that will be routine when ESO's European Extremely Large Telescope - which will be the biggest optical and near infrared telescope in the world - becomes operational." Notes [1] An earlier ESO result (eso0405) reported an object at a larger distance (a redshift of 10). However, further work failed to find an object of similar brightness at this position, and more recent observations with the NASA/Hubble Space Telescope have been inconclusive. The identification of this object with a galaxy at very high redshift is no longer considered to be valid by most astronomers. [2] When the Universe cooled down after the Big Bang, about 13.7 billion years ago, electrons and protons combined to form hydrogen gas. This cool dark gas was the main constituent of the Universe during the so-called Dark Ages, when there were no luminous objects. This phase eventually ended when the first stars formed and their intense ultraviolet radiation slowly made the hydrogen fog transparent again by splitting the hydrogen atoms back into electrons and protons, a process known as reionisation. This epoch in the Universe's early history lasted from about 150 million to 800 million years after the Big Bang. Understanding how reionisation happened and how the first galaxies formed and evolved is one of the major challenges of modern cosmology. [3] These Hubble observations are described at: http://www.spacetelescope.org/news/heic1001/ [4] Astronomers have two main ways of finding and measuring the distances to the earliest galaxies. They can take very deep images through differently coloured filters and measure the brightness of many objects at different wavelengths. They can then compare these with what is expected of galaxies of different types at different times in the Universe's history. This is the only way currently available to discover these very faint galaxies and is the technique employed by the Hubble team. But this technique is not always reliable. For example, what may seem to be a faint, very distant galaxy can sometimes turn out to be a mundane, cool star in our Milky Way. Once candidate objects are found more reliable estimates of the distance (measured as the redshift) can be obtained by splitting the light from a candidate object up into its component colours and looking for the telltale signs of emission from hydrogen or other elements in the galaxy. This spectroscopic approach is the only means by which astronomers can obtain the most reliable and accurate measurements of distance. [5] The strange name indicates that it was found in the Ultra Deep Field search area and the number gives its precise position on the sky. More information An online press conference to announce the new results and offer journalists the opportunity for discussion with the scientists will be held at 16:00 CEST on Tuesday, 19 October 2010. To participate in the teleconference, bona-fide members of the media must get accredited by contacting Douglas Pierce-Price by email (dpiercep@eso.org). Reporters will need access to a computer with a recent version of Adobe Flash Player installed and a broadband internet connection. This research was presented in a paper, Spectroscopic confirmation of a galaxy at redshift z=8.6, Lehnert et al., to appear in Nature on 21 October 2010. The team is composed of M. D. Lehnert (Observatoire de Paris - Laboratoire GEPI / CNRS-INSU / Université Paris Diderot, France), N. P. H. Nesvadba (Institut d'Astrophysique Spatiale / CNRS-INSU / Université Paris-Sud, France), J.-G.Cuby (Laboratoire d'Astrophysique de Marseille / CNRS-INSU / Université de Provence, France), A. M. Swinbank (Durham University, UK), S. Morris (Durham University, UK), B. Clément (Laboratoire d'Astrophysique de Marseille / CNRS-INSU / Université de Provence, France), C. J. Evans (UK Astronomy Technology Centre, Edinburgh, UK), M. N. Bremer (University of Bristol, UK) and S. Basa (Laboratoire d'Astrophysique de Marseille / CNRS-INSU / Université de Provence, France). ESO, the European Southern Observatory, is the foremost intergovernmental astronomy organisation in Europe and the world's most productive astronomical observatory. It is supported by 14 countries: Austria, Belgium, the Czech Republic, Denmark, France, Finland, Germany, Italy, the Netherlands, Portugal, Spain, Sweden, Switzerland and the United Kingdom. ESO carries out an ambitious programme focused on the design, construction and operation of powerful ground-based observing facilities enabling astronomers to make important scientific discoveries. ESO also plays a leading role in promoting and organising cooperation in astronomical research. ESO operates three unique world-class observing sites in Chile: La Silla, Paranal and Chajnantor. At Paranal, ESO operates the Very Large Telescope, the world's most advanced visible-light astronomical observatory and VISTA, the world's largest survey telescope. ESO is the European partner of a revolutionary astronomical telescope ALMA, the largest astronomical project in existence. ESO is currently planning a 42-metre European Extremely Large optical/near-infrared Telescope, the E-ELT, which will become "the world's biggest eye on the sky".

Modeling bistatic spectral measurements of temporally evolving reflected and emitted energy from a distant and receding target

NASA Astrophysics Data System (ADS)

Cusumano, Salvatore J.; Fiorino, Steven T.; Bartell, Richard J.; Krizo, Matthew J.; Bailey, William F.; Beauchamp, Rebecca L.; Marciniak, Michael A.

2011-01-01

The Air Force Institute of Technology's Center for Directed Energy developed the High Energy Laser End-to-End Operational Simulation (HELEEOS) model in part to quantify the performance variability in laser propagation created by the natural environment during dynamic engagements. As such, HELEEOS includes a fast-calculating, first principles, worldwide surface-to-100 km, atmospheric propagation, and characterization package. This package enables the creation of profiles of temperature, pressure, water vapor content, optical turbulence, atmospheric particulates, and hydrometeors as they relate to line-by-line layer transmission, path, and background radiance at wavelengths from the ultraviolet to radio frequencies. In the current paper an example of a unique high fidelity simulation of a bistatic, time-varying five band multispectral remote observation of energy delivered on a distant and receding test object is presented for noncloudy conditions with aerosols. The multispectral example emphasizes atmospheric effects using HELEEOS, the interaction of the energy and the test object, the observed reflectance, and subsequent hot spot generated. A model of a sensor suite located on the surface is included to collect the diffuse reflected in-band laser radiation and the emitted radiance of the hot spot in four separate and spatially offset midwave infrared and longwave infrared bands. Particular care is taken in modeling the bidirectional reflectance distribution function of the delivered energy/target interaction to account for both the coupling of energy into the test object and the changes in reflectance as a function of temperature. The architecture supports any platform-target-observer geometry, geographic location, season, and time of day, and it provides for correct contributions of the sky-earth background. The simulation accurately models the thermal response, kinetics, turbulence, base disturbance, diffraction, and signal-to-noise ratios.

Incidence and sites of distant metastases from head and neck cancer.

PubMed

Ferlito, A; Shaha, A R; Silver, C E; Rinaldo, A; Mondin, V

2001-01-01

The incidence of distant metastases in head and neck squamous cell carcinoma (SCC) is relatively small in comparison to other malignancies. Distant metastases adversely impact survival and may significantly affect treatment planning. The incidence of distant metastases is influenced by location of the primary tumor, initial T and N stage of the neoplasm, and the presence or absence of regional control above the clavicle. Patients with advanced nodal disease have a high incidence of distant metastases, particularly in the presence of jugular vein invasion or extensive soft tissue disease in the neck. Primary tumors of advanced T stages in the hypopharynx, oropharynx and oral cavity are associated with the highest incidence of distant metastases. Pulmonary metastases are the most frequent in SCC, accounting for 66% of distant metastases. It may be difficult to distinguish pulmonary metastasis from a new primary tumor, particularly if solitary. Other metastatic sites include bone (22%), liver (10%), skin, mediastinum and bone marrow. An important question remains as to how intensely pre- and postoperative screening for distant metastases should be performed. Preoperative chest X-ray is warranted in all cases. If the primary tumor and nodal status place the patient at high risk for pulmonary metastasis, then preoperative computed tomography scan of the chest should be done. Screening for distant metastases at other sites is usually not indicated in SCC of the upper aerodigestive tract. Postoperatively, annual X-rays of the chest are usually sufficient, but in high-risk situations a chest X-ray performed every 3-6 months may be beneficial. Certain histologic types of primary tumor have greater or lesser propensity to metastasize distantly, and have a different natural history. Adenoid cystic carcinoma metastasizes frequently, even in the absence of extensive local or regional disease. Basaloid squamous cell carcinoma and neuroendocrine carcinomas also metastasize widely. Extensive evaluation for distant metastases is justified for these tumors. Knowledge of the natural history of various neoplasms and the factors that contribute to distant metastases as well as good judgement are essential for cost-effective treatment planning and decision-making with regard to pre- and postoperative evaluation for distant metastases in cancer of the head and neck. Copyright 2001 S. Karger AG, Basel

Hubble Spotlights a Celestial Sidekick

NASA Image and Video Library

2017-12-08

This image was captured by the NASA/ESA Hubble Space Telescope’s Advanced Camera for Surveys (ACS), a highly efficient wide-field camera covering the optical and near-infrared parts of the spectrum. While this lovely image contains hundreds of distant stars and galaxies, one vital thing is missing — the object Hubble was actually studying at the time! This is not because the target has disappeared. The ACS actually uses two detectors: the first captures the object being studied — in this case an open star cluster known as NGC 299 — while the other detector images the patch of space just ‘beneath’ it. This is what can be seen here. Technically, this picture is merely a sidekick of the actual object of interest — but space is bursting with activity, and this field of bright celestial bodies offers plenty of interest on its own. It may initially seem to show just stars, but a closer look reveals many of these tiny objects to be galaxies. The spiral galaxies have arms curving out from a bright center. The fuzzier, less clearly shaped galaxies might be ellipticals. Some of these galaxies contain millions or even billions of stars, but are so distant that all of their starry residents are contained within just a small pinprick of light that appears to be the same size as a single star! The bright blue dots are very hot stars, sometimes distorted into crosses by the struts supporting Hubble’s secondary mirror. The redder dots are cooler stars, possibly in the red giant phase when a dying star cools and expands. Credit: ESA/Hubble & NASA NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

In Vivo Clotting Breast Cancer Stem Cells and Platelets: A New Endogenous Precursor of Metastasis Progression

DTIC Science & Technology

2013-05-01

different magnifications (objective lenses of ×10, ×20, ×40 and ×100). To verify metastatic disease, multiple organs were also used for histological...indicate the influence of metastasis in the distant organs or cancer recurrence in the pri- mary tumor site. Although the animal model was used in... ORGANIZATION : University of Arkansas Little Rock AR 72205-7101 REPORT DATE: 2013 TYPE OF REPORT: Final PREPARED FOR: U.S. Army Medical

Effects of a Hypertension Management Program by Seongcheon Primary Health Care Post in South Korea: An Analysis of Changes in the Level of Knowledge of Hypertension in the Period from 2004 to 2009

ERIC Educational Resources Information Center

Song, In Han; Kim, Sang-A; Park, Woong-Sub

2012-01-01

The objective of this study was to examine the effects of a hypertension management program provided by a primary health care post located in a distant rural area in South Korea on the level of knowledge of hypertension. The panel data consisted of a total of 319 people or the entire population aged above 40 years of five villages located in…

Depth-aware image seam carving.

PubMed

Shen, Jianbing; Wang, Dapeng; Li, Xuelong

2013-10-01

Image seam carving algorithm should preserve important and salient objects as much as possible when changing the image size, while not removing the secondary objects in the scene. However, it is still difficult to determine the important and salient objects that avoid the distortion of these objects after resizing the input image. In this paper, we develop a novel depth-aware single image seam carving approach by taking advantage of the modern depth cameras such as the Kinect sensor, which captures the RGB color image and its corresponding depth map simultaneously. By considering both the depth information and the just noticeable difference (JND) model, we develop an efficient JND-based significant computation approach using the multiscale graph cut based energy optimization. Our method achieves the better seam carving performance by cutting the near objects less seams while removing distant objects more seams. To the best of our knowledge, our algorithm is the first work to use the true depth map captured by Kinect depth camera for single image seam carving. The experimental results demonstrate that the proposed approach produces better seam carving results than previous content-aware seam carving methods.

A review of statistical methods to analyze extreme precipitation and temperature events in the Mediterranean region

NASA Astrophysics Data System (ADS)

Lazoglou, Georgia; Anagnostopoulou, Christina; Tolika, Konstantia; Kolyva-Machera, Fotini

2018-04-01

The increasing trend of the intensity and frequency of temperature and precipitation extremes during the past decades has substantial environmental and socioeconomic impacts. Thus, the objective of the present study is the comparison of several statistical methods of the extreme value theory (EVT) in order to identify which is the most appropriate to analyze the behavior of the extreme precipitation, and high and low temperature events, in the Mediterranean region. The extremes choice was made using both the block maxima and the peaks over threshold (POT) technique and as a consequence both the generalized extreme value (GEV) and generalized Pareto distributions (GPDs) were used to fit them. The results were compared, in order to select the most appropriate distribution for extremes characterization. Moreover, this study evaluates the maximum likelihood estimation, the L-moments and the Bayesian method, based on both graphical and statistical goodness-of-fit tests. It was revealed that the GPD can characterize accurately both precipitation and temperature extreme events. Additionally, GEV distribution with the Bayesian method is proven to be appropriate especially for the greatest values of extremes. Another important objective of this investigation was the estimation of the precipitation and temperature return levels for three return periods (50, 100, and 150 years) classifying the data into groups with similar characteristics. Finally, the return level values were estimated with both GEV and GPD and with the three different estimation methods, revealing that the selected method can affect the return level values for both the parameter of precipitation and temperature.

Judging near and distant virtue and vice ☆

PubMed Central

Eyal, Tal; Liberman, Nira; Trope, Yaacov

2009-01-01

We propose that people judge immoral acts as more offensive and moral acts as more virtuous when the acts are psychologically distant than near. This is because people construe more distant situations in terms of moral principles, rather than attenuating situation-specific considerations. Results of four studies support these predictions. Study 1 shows that more temporally distant transgressions (e.g., eating one's dead dog) are construed in terms of moral principles rather than contextual information. Studies 2 and 3 further show that morally offensive actions are judged more severely when imagined from a more distant temporal (Study 2) or social (Study 3) perspective. Finally, Study 4 shows that moral acts (e.g., adopting a disabled child) are judged more positively from temporal distance. The findings suggest that people more readily apply their moral principles to distant rather than proximal behaviors. PMID:19554217

Quantifying population exposure to airborne particulate matter during extreme events in California due to climate change

NASA Astrophysics Data System (ADS)

Mahmud, A.; Hixson, M.; Kleeman, M. J.

2012-02-01

The effect of climate change on population-weighted concentrations of particulate matter (PM) during extreme events was studied using the Parallel Climate Model (PCM), the Weather Research and Forecasting (WRF) model and the UCD/CIT 3-D photochemical air quality model. A "business as usual" (B06.44) global emissions scenario was dynamically downscaled for the entire state of California between the years 2000-2006 and 2047-2053. Air quality simulations were carried out for 1008 days in each of the present-day and future climate conditions using year-2000 emissions. Population-weighted concentrations of PM0.1, PM2.5, and PM10 total mass, components species, and primary source contributions were calculated for California and three air basins: the Sacramento Valley air basin (SV), the San Joaquin Valley air basin (SJV) and the South Coast Air Basin (SoCAB). Results over annual-average periods were contrasted with extreme events. Climate change between 2000 vs. 2050 did not cause a statistically significant change in annual-average population-weighted PM2.5 mass concentrations within any major sub-region of California in the current study. Climate change did alter the annual-average composition of the airborne particles in the SoCAB, with notable reductions of elemental carbon (EC; -3%) and organic carbon (OC; -3%) due to increased annual-average wind speeds that diluted primary concentrations from gasoline combustion (-3%) and food cooking (-4%). In contrast, climate change caused significant increases in population-weighted PM2.5 mass concentrations in central California during extreme events. The maximum 24-h average PM2.5 concentration experienced by an average person during a ten-year period in the SJV increased by 21% due to enhanced production of secondary particulate matter (manifested as NH4NO3). In general, climate change caused increased stagnation during future extreme pollution events, leading to higher exposure to diesel engines particles (+32%) and wood combustion particles (+14%) when averaging across the population of the entire state. Enhanced stagnation also isolated populations from distant sources such as shipping (-61%) during extreme events. The combination of these factors altered the statewide population-averaged composition of particles during extreme events, with EC increasing by 23%, nitrate increasing by 58%, and sulfate decreasing by 46%.

Quantifying population exposure to airborne particulate matter during extreme events in California due to climate change

NASA Astrophysics Data System (ADS)

Mahmud, A.; Hixson, M.; Kleeman, M. J.

2012-08-01

The effect of climate change on population-weighted concentrations of particulate matter (PM) during extreme pollution events was studied using the Parallel Climate Model (PCM), the Weather Research and Forecasting (WRF) model and the UCD/CIT 3-D photochemical air quality model. A "business as usual" (B06.44) global emissions scenario was dynamically downscaled for the entire state of California between the years 2000-2006 and 2047-2053. Air quality simulations were carried out for 1008 days in each of the present-day and future climate conditions using year-2000 emissions. Population-weighted concentrations of PM0.1, PM2.5, and PM10 total mass, components species, and primary source contributions were calculated for California and three air basins: the Sacramento Valley air basin (SV), the San Joaquin Valley air basin (SJV) and the South Coast Air Basin (SoCAB). Results over annual-average periods were contrasted with extreme events. The current study found that the change in annual-average population-weighted PM2.5 mass concentrations due to climate change between 2000 vs. 2050 within any major sub-region in California was not statistically significant. However, climate change did alter the annual-average composition of the airborne particles in the SoCAB, with notable reductions of elemental carbon (EC; -3%) and organic carbon (OC; -3%) due to increased annual-average wind speeds that diluted primary concentrations from gasoline combustion (-3%) and food cooking (-4%). In contrast, climate change caused significant increases in population-weighted PM2.5 mass concentrations in central California during extreme events. The maximum 24-h average PM2.5 concentration experienced by an average person during a ten-yr period in the SJV increased by 21% due to enhanced production of secondary particulate matter (manifested as NH4NO3). In general, climate change caused increased stagnation during future extreme pollution events, leading to higher exposure to diesel engines particles (+32%) and wood combustion particles (+14%) when averaging across the population of the entire state. Enhanced stagnation also isolated populations from distant sources such as shipping (-61%) during extreme events. The combination of these factors altered the statewide population-averaged composition of particles during extreme events, with EC increasing by 23 %, nitrate increasing by 58%, and sulfate decreasing by 46%.

[The Role of Supraclavicular lymph node dissection in Breast Cancer Patients with Synchronous Ipsilateral Supraclavicular Lymph Node Metastasis].

PubMed

Zhang, W; Qi, X M; Chen, A X; Zhang, P; Cao, X C; Xiao, C H

2017-05-23

Objective: In this study, we evaluated the effect of supraclavicular lymph node dissection in breast cancer patients who presented with ipsilateral supraclavicular lymph node metastasis (ISLM) without distant metastasis. Methods: A total of 90 patients with synchronous ISLM without distant metastasis between 2000 and 2009 were retrospectively analyzed. Patients were retrospectively divided into two groups, namely supraclavicular lymph node dissection group(34 patients) and non-dissection group(56 patients), according to whether they underwentsupraclavicular lymph node dissection or not.The Kaplan-Meier method was applied to analyze the locoregional relapse free survival (LRFS) and overall survival(OS). Results: Median follow-upwas 85 months(range, 6 to 11 months). Local recurrence in 32 cases, 47 cases of distant metastasis, of which 25 patients were accompanied by both locoregional relapse and distant metastasis. Of the 32 patients with locoregional relapse, 11 patients were in the lymph node dissection group and 21 patients in the control group. Of the 47 patients with distant metastases, 17 were treated with lymph node dissection, 30 in the control group. Thirty-two patients died in the whole group and 16 patients underwentlymph node dissection and 16 patients didn't. There was no significant difference between the rate of 5-year LRFS and 5-year OS ( P =0.359, P =0.246). For patients of ER negative, the 5-year loco-regional relapse free survival rates were 63.7% and 43.3% in supraclavicular lymph node dissection group and control group, respectively. The 5-year overall survival rates were 52.1% and 52.3%, respectively, and there were no statistically significant differences ( P =0.118, P =0.951). For patients of PR negative, the 5-yearloco-regional relapse free rates were 59.8% and 46.2%, respectively, and the 5-year overall survival rates were 50.6% and 43.2%, respectively, and there was no significant difference between the two groups ( P =0.317, P =0.973). The 5-year recurrence-free survival rates of human epidermal growth factor receptor 2 (HER2)-positive patients were 61.2% and 48.0%( P =0.634), respectively, and the 5-year overall survival rates were 37.2% and 65.4%( P =0.032). Forty-seven patients suffered distant metastases and the 5-year metastases free survival rates were 37.3% and 38.5% in supraclavicular lymph node dissection group and control group, respectively. Conclusion: Supraclavicular lymph node dissection maybe an effective approach to improve the loco-regional control for the patients with ISLM, especially for ER negative and PR negative subtypes, but it might has adverseeffects for the patients with negative HER2 status.

ROSAT Discovers Unique, Distant Cluster of Galaxies

NASA Astrophysics Data System (ADS)

1995-06-01

Brightest X-ray Cluster Acts as Strong Gravitational Lens Based on exciting new data obtained with the ROSAT X-ray satellite and a ground-based telescope at the ESO La Silla Observatory, a team of European astronomers [2] has just discovered a very distant cluster of galaxies with unique properties. It emits the strongest X-ray emission of any cluster ever observed by ROSAT and is accompanied by two extraordinarily luminous arcs that represent the gravitationally deflected images of even more distant objects. The combination of these unusual characteristics makes this cluster, now known as RXJ1347.5-1145, a most interesting object for further cosmological studies. DISCOVERY AND FOLLOW-UP OBSERVATIONS This strange cluster of galaxies was discovered during the All Sky Survey with the ROSAT X-ray satellite as a moderately intense X-ray source in the constellation of Virgo. It could not be identified with any already known object and additional ground-based observations were therefore soon after performed with the Max-Planck-Society/ESO 2.2-metre telescope at the La Silla observatory in Chile. These observations took place within a large--scale redshift survey of X-ray clusters of galaxies detected by the ROSAT All Sky Survey, a so-called ``ESO Key Programme'' led by astronomers from the Max-Planck-Institut fur Extraterrestrische Physik and the Osservatorio Astronomico di Brera. The main aim of this programme is to identify cluster X-ray sources, to determine the distance to the X-ray emitting clusters and to investigate their overall properties. These observations permitted to measure the redshift of the RXJ1347.5-1145 cluster as z = 0.45, i.e. it moves away from us with a velocity (about 106,000 km/sec) equal to about one-third of the velocity of light. This is an effect of the general expansion of the universe and it allows to determine the distance as about 5,000 million light-years (assuming a Hubble constant of 75 km/sec/Mpc). In other words, we see these galaxies as they were 5,000 million years ago. Knowing the intensity of the X-ray emission as measured by ROSAT and also the distance, the astronomers were then able to estimate the total X-ray energy emitted by this cluster. It was found to be extremely high [3], in fact higher than that of any other cluster ever observed by ROSAT. It amounts to no less than 1.5 million million times the total energy emitted by the Sun. It is believed that this strong X-ray emission originates in a hot gas located between the galaxies in the cluster. The high temperature indicates that the components of the gas move very rapidly; this is related to the strong gravitational field within the cluster. THE GRAVITATIONAL ARCS To their great surprise and delight, the astronomers also discovered two bright arcs, 5 - 6 arcseconds long and symmetrically placed about 35 arcseconds to the North-East and South-West of the brightest galaxies in the cluster (see the photo). They were detected on exposures of only 3 minutes duration with the 2.2-metre telescope and are among the brightest such arcs ever found. At the indicated distance, the arcs are situated at a projected distance of about 500,000 light-years from the centre of the cluster. It is an interesting possibility that the two arcs may in fact be two images of the same, very distant galaxy, that is situated far beyond RXJ1347.5-1145 and whose light has been bent and split by this cluster's strong gravitational field. This strange phenomenon was first discovered in the late 1970's and is referred to as gravitational lensing. Quite a few examples are now known, in most cases in the form of double or multiple images of quasars. About three dozen cases involve well visible galaxy clusters and elongated arcs, but few, if any, of these arcs are as bright as those seen in the present cluster. This particular arc configuration enables a very accurate determination of the total mass of the cluster, once the distance of the background galaxy has been measured (by obtaining spectra of the arcs and measuring their redshift). The masses of galaxy clusters are important for the determination, for instance of the mean density and distribution of matter in the universe. This is because these clusters are the most massive, clearly defined objects known and as such trace these parameters in the universe on very large scales. Another possibility to derive the cluster mass is offered by X-ray observations, because the distribution of the hot, X-ray emitting gas traces the gravitational field of the cluster. Recently, in some clusters there has been a discrepancy between the mass determined in this way and that found from gravitational lensing effects. The team of astronomers now hopes that follow-up X-ray observations of RXJ1347.5-1145 will help to solve this puzzle. Moreover, the combination of extremely high X-ray brightness and the possibility to perform a rather accurate mass determination by the gravitational lensing effect makes this particular cluster a truly unique object. In view of the exceptional X-ray brightness, a very high mass is expected. The exact determination will be possible, as soon as spectra have been obtained of the two arcs. Contrary to what is the case in other clusters, this will not be so difficult, due to their unusual brightness and their ideal geometrical configuration. [1] This is a joint Press Release of ESO and the Max-Planck-Society. It is accompanied by a B/W photo. [2] The investigation described in this Press Release is the subject of a Letter to the Editor which will soon appear in the European journal Astronomy & Astrophysics, with the following authors: Sabine Schindler (Max-Planck-Institut fuer Extraterrestrische Physik and Max-Planck-Institut fuer Astrophysik, Garching, Germany), Hans Boehringer, Doris M. Neumann and Ulrich G. Briel (Max-Planck-Institut fuer Extraterrestrische Physik, Garching, Germany), Luigi Guzzo (Osservatorio Astronomico di Brera, Merate, Italy), Guido Chincarini (Osservatorio Astronomico di Brera, Merate, and Dipartimento di Fisica, Universita di Milano, Italy), Harald Ebeling (Institute of Astronomy, Cambridge, U.K.), Chris A. Collins (School of Chemical and Physical Sciences, John-Moores University, Liverpool, U.K.), Sabrina De Grandi (Dipartimento di Fisica, Universita di Milano, Italy), Peter Shaver (ESO, Garching, Germany) and Giampaolo Vettolani (Istituto di Radioastronomia del CNR, Bologna, Italy). [3] The total X-ray energy emitted by RXJ1347.5-1145 is (6.2 +-0.6) 10^45 erg s-1 in the range 0.1--2.4 keV. ESO Press Information is made available on the World-Wide Web (URL: http://www.hq.eso.org/) and on CompuServe (space science and astronomy area, GO SPACE)

Extreme Radio Flares and Associated X-Ray Variability from Young Stellar Objects in the Orion Nebula Cluster

DOE Office of Scientific and Technical Information (OSTI.GOV)

Forbrich, Jan; Reid, Mark J.; Wolk, Scott J.

Young stellar objects are known to exhibit strong radio variability on timescales of weeks to months, and a few reports have documented extreme radio flares with at least an order of magnitude change in flux density on timescales of hours to days. However, there have been few constraints on the occurrence rate of such radio flares or on the correlation with pre-main sequence X-ray flares, although such correlations are known for the Sun and nearby active stars. Here we report simultaneous deep VLA radio and Chandra X-ray observations of the Orion Nebula Cluster, targeting hundreds of sources to look formore » the occurrence rate of extreme radio variability and potential correlation with the most extreme X-ray variability. We identify 13 radio sources with extreme radio variability, with some showing an order of magnitude change in flux density in less than 30 minutes. All of these sources show X-ray emission and variability, but we find clear correlations with extreme radio flaring only on timescales <1 hr. Strong X-ray variability does not predict the extreme radio sources and vice versa. Radio flares thus provide us with a new perspective on high-energy processes in YSOs and the irradiation of their protoplanetary disks. Finally, our results highlight implications for interferometric imaging of sources violating the constant-sky assumption.« less

Biogeography in Cellana (Patellogastropoda, Nacellidae) with Special Emphasis on the Relationships of Southern Hemisphere Oceanic Island Species

PubMed Central

Nakano, Tomoyuki; Palma, Alvaro; Poulin, Elie

2017-01-01

Oceanic islands lacking connections to other land are extremely isolated from sources of potential colonists and have acquired their biota mainly through dispersal from geographically distant areas. Hence, isolated island biota constitutes interesting models to infer biogeographical mechanisms of dispersal, colonization, differentiation, and speciation. Limpets of the genus Cellana (Nacellidae: Patellogastropoda) show limited dispersal capacity but are broadly distributed across the Indo-Pacific including many endemic species in isolated oceanic islands. Here, we examined main distributional patterns and geographic boundaries among Cellana lineages with special emphasis in the relationships of Southern Hemisphere oceanic islands species. Phylogenetic reconstructions based on mtDNA (COI) recognized three main clades in Cellana including taxa from different provinces of the Indo-Pacific. Clear genetic discontinuities characterize the biogeography of Cellana and several lineages are associated to particular areas of the Indo-Pacific supporting the low dispersal capacity of the genus across recognized biogeographical barriers in the region. However, evolutionary relationships within Cellana suggest that long-distance dispersal processes have been common in the history of the genus and probably associated to the origin of the species in Hawaii and Juan Fernández Archipelago. Therefore, the presence of Cellana species in geographically distant Southern Hemisphere oceanic islands, such as the Juan Fernández Archipelago, suggests that long-distance dispersal mediated by rafting may have played an important role in the biogeography of the genus. PMID:28099466

Hubble Captures Massive Dead Disk Galaxy that Challenges Theories of Galaxy Evolution

NASA Image and Video Library

2017-12-08

By combining the power of a "natural lens" in space with the capability of NASA's Hubble Space Telescope, astronomers made a surprising discovery—the first example of a compact yet massive, fast-spinning, disk-shaped galaxy that stopped making stars only a few billion years after the big bang. Finding such a galaxy early in the history of the universe challenges the current understanding of how massive galaxies form and evolve, say researchers. Read more: go.nasa.gov/2sWwKkc caption: Acting as a “natural telescope” in space, the gravity of the extremely massive foreground galaxy cluster MACS J2129-0741 magnifies, brightens, and distorts the far-distant background galaxy MACS2129-1, shown in the top box. The middle box is a blown-up view of the gravitationally lensed galaxy. In the bottom box is a reconstructed image, based on modeling that shows what the galaxy would look like if the galaxy cluster were not present. The galaxy appears red because it is so distant that its light is shifted into the red part of the spectrum. Credits: NASA, ESA, M. Postman (STScI), and the CLASH team NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

Outbreeding effects in an inbreeding insect, Cimex lectularius.

PubMed

Fountain, Toby; Butlin, Roger K; Reinhardt, Klaus; Otti, Oliver

2015-01-01

In some species, populations with few founding individuals can be resilient to extreme inbreeding. Inbreeding seems to be the norm in the common bed bug, Cimex lectularius, a flightless insect that, nevertheless, can reach large deme sizes and persist successfully. However, bed bugs can also be dispersed passively by humans, exposing inbred populations to gene flow from genetically distant populations. The introduction of genetic variation through this outbreeding could lead to increased fitness (heterosis) or be costly by causing a loss of local adaptation or exposing genetic incompatibility between populations (outbreeding depression). Here, we addressed how inbreeding within demes and outbreeding between distant populations impact fitness over two generations in this re-emerging public health pest. We compared fitness traits of families that were inbred (mimicking reproduction following a founder event) or outbred (mimicking reproduction following a gene flow event). We found that outbreeding led to increased starvation resistance compared to inbred families, but this benefit was lost after two generations of outbreeding. No other fitness benefits of outbreeding were observed in either generation, including no differences in fecundity between the two treatments. Resilience to inbreeding is likely to result from the history of small founder events in the bed bug. Outbreeding benefits may only be detectable under stress and when heterozygosity is maximized without disruption of coadaptation. We discuss the consequences of these results both in terms of inbreeding and outbreeding in populations with genetic and spatial structuring, as well as for the recent resurgence of bed bug populations.

Differences in patterns of survival in metastatic adenoid cystic carcinoma of the head and neck.

PubMed

van Weert, Stijn; Reinhard, Rinze; Bloemena, Elisabeth; Buter, Jan; Witte, Birgit I; Vergeer, Marije R; Leemans, C René

2017-03-01

We examined the assumption in conventional teaching about metastatic adenoid cystic carcinoma (ACC) being an indolent type of disease. A single center analysis of 105 cases of ACC was performed. Radiographs were reviewed and tumor response to chemotherapy was measured. Distant disease-free survival (DDFS) and time to death since distant metastases diagnosis were analyzed. Forty-two percent of the patients were diagnosed with distant metastases. DDFS showed significant negative associations with advanced T classification, N+ classification, solid type tumor, and positive surgical margins. Distant metastases (91%) developed in the first 5 years after presentation. Median distant metastatic survival was 13.8 months. The most frequent organ sited was the lung. Solid type ACC showed a preponderance for multiorgan metastases (17/28; 61%). Distant metastases seemed not to occur in case of clear surgical margins. Solid type ACC had a significant poorer survival after development of distant metastases. Metastatic ACC is not always an indolent disease. © 2016 Wiley Periodicals, Inc. Head Neck 39: 456-463, 2017. © 2016 Wiley Periodicals, Inc.

Early working memory as a racially and ethnically neutral measure of outcome in extremely preterm children at 18-22 months

PubMed Central

Lowe, Jean R.; Duncan, Andrea Freeman; Bann, Carla M.; Fuller, Janell; Hintz, Susan R.; Das, Abhik; Higgins, Rosemary D.; Watterberg, Kristi L.

2013-01-01

Background Difficulties with executive function has been found in preterm children, resulting in difficulties with learning and school performance. Aim This study evaluated the relationship of early working memory as measured by object permanence items to the cognitive and language scores on the Bayley Scales-III in a cohort of children born extremely preterm. Study Design Logistic regression models were conducted to compare object permanence scores derived from the Bayley Scales-III by race/ethnicity and maternal education, controlling for medical covariates. Subjects Extremely preterm toddlers (526), who were part of a Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network's multi-center study, were evaluated at 18-22 months corrected age. Outcome Measures Object permanence scores derived from the Bayley Developmental Scales were compared by race/ethnicity and maternal education, controlling for medical covariates. Results There were no significant differences in object permanence mastery and scores among the treatment groups after controlling for medical and social variables, including maternal education and race/ethnicity. Males and children with intraventricular hemorrhage, retinopathy of prematurity, and bronchopulmonary dysplasia were less likely to demonstrate object permanence mastery and had lower object permanence scores. Children who attained object permanence mastery had significantly higher Bayley Scales-III cognitive and language scores after controlling for medical and socio-economic factors. Conclusions Our measure of object permanence is free of influence from race, ethnic and socio-economic factors. Adding this simple task to current clinical practice could help detect early executive function difficulties in young children. PMID:23993309

Early working memory as a racially and ethnically neutral measure of outcome in extremely preterm children at 18-22 months.

PubMed

Lowe, Jean R; Duncan, Andrea Freeman; Bann, Carla M; Fuller, Janell; Hintz, Susan R; Das, Abhik; Higgins, Rosemary D; Watterberg, Kristi L

2013-12-01

Difficulties with executive function have been found in preterm children, resulting in difficulties with learning and school performance. This study evaluated the relationship of early working memory as measured by object permanence items to the cognitive and language scores on the Bayley Scales-III in a cohort of children born extremely preterm. Logistic regression models were conducted to compare object permanence scores derived from the Bayley Scales-III by race/ethnicity and maternal education, controlling for medical covariates. Extremely preterm toddlers (526), who were part of a Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network's multi-center study, were evaluated at 18-22 months corrected age. Object permanence scores derived from the Bayley Developmental Scales were compared by race/ethnicity and maternal education, controlling for medical covariates. There were no significant differences in object permanence mastery and scores among the treatment groups after controlling for medical and social variables, including maternal education and race/ethnicity. Males and children with intraventricular hemorrhage, retinopathy of prematurity, and bronchopulmonary dysplasia were less likely to demonstrate object permanence mastery and had lower object permanence scores. Children who attained object permanence mastery had significantly higher Bayley Scales-III cognitive and language scores after controlling for medical and socio-economic factors. Our measure of object permanence is free of influence from race, ethnic and socio-economic factors. Adding this simple task to current clinical practice could help detect early executive function difficulties in young children. Published by Elsevier Ireland Ltd.

Observing heliospheric neutral atoms at 1 AU

NASA Astrophysics Data System (ADS)

Heerikhuisen, Jacob; Pogorelov, Nikolai; Florinski, Vladimir; Zank, Gary

2006-09-01

Although in situ observations of distant heliospheric plasma by the Voyagers has proven to be extremely enlightening, such point observations need to be complemented with global measurements taken remotely to obtain a complete picture of the heliosphere and local interstellar environment. Neutral atoms, with their contempt for magnetic fields, provide useful probes of the plasma that generated them. However, there will be a number of ambiguities in neutral atom readings that require a deeper understanding of the plasma processes generating neutral atoms, as well as the loss mechanisms on their flight to the observation point. We introduce a procedure for generating all-sky maps of energetic H-atoms, calculated directly in our Monte-Carlo neutral atom code. Results obtained for a self-consistent axisymmetric MHD-Boltzmann calculation, as well as several non-selfconsistent 3D sky maps, will be presented.

GRB 130427A: A Nearby Ordinary Monster

NASA Technical Reports Server (NTRS)

Maselli, A.; Melandri, A.; Nava, L.; Mundell, C. G.; Kawai, N.; Campana, S.; Covino, S.; Cummings, J. R.; Cusumano, G.; Evans, P. A.;

Molecular parameters of head and neck cancer metastasis

PubMed Central

Bhave, Sanjay L.; Teknos, Theodoros N.; Pan, Quintin; James, Arthur G.; Solove, Richard J.

2011-01-01

Metastasis remains a major cause of mortality in patients with head and neck squamous cell carcinoma (HNSCC). HNSCC patients with metastatic disease have extremely poor prognosis with survival rate of less than a year. Metastasis is an intricate sequential process which requires a discrete population of tumor cells to possess the capacity to intravasate from the primary tumor into systemic circulation, survive in circulation, extravasate at a distant site, and proliferate in a foreign hostile environment. Literature has accumulated to provide mechanistic insight into several signal transduction pathways, receptor tyrosine kinases (RTKs), signal transducer and activator of transcription 3 (Stat3), Rho GTPases, protein kinase Cε (PKCε), and nuclear factor-κB (NF-κB), that are involved in mediating a metastatic tumor cell phenotype in HNSCC. Here we highlight accrued information regarding the key molecular parameters of HNSCC metastasis. PMID:22077153

GRB 130427A: a nearby ordinary monster.

PubMed

Maselli, A; Melandri, A; Nava, L; Mundell, C G; Kawai, N; Campana, S; Covino, S; Cummings, J R; Cusumano, G; Evans, P A; Ghirlanda, G; Ghisellini, G; Guidorzi, C; Kobayashi, S; Kuin, P; La Parola, V; Mangano, V; Oates, S; Sakamoto, T; Serino, M; Virgili, F; Zhang, B-B; Barthelmy, S; Beardmore, A; Bernardini, M G; Bersier, D; Burrows, D; Calderone, G; Capalbi, M; Chiang, J; D'Avanzo, P; D'Elia, V; De Pasquale, M; Fugazza, D; Gehrels, N; Gomboc, A; Harrison, R; Hanayama, H; Japelj, J; Kennea, J; Kopac, D; Kouveliotou, C; Kuroda, D; Levan, A; Malesani, D; Marshall, F; Nousek, J; O'Brien, P; Osborne, J P; Pagani, C; Page, K L; Page, M; Perri, M; Pritchard, T; Romano, P; Saito, Y; Sbarufatti, B; Salvaterra, R; Steele, I; Tanvir, N; Vianello, G; Wiegand, B; Weigand, B; Wiersema, K; Yatsu, Y; Yoshii, T; Tagliaferri, G

2014-01-03

Long-duration gamma-ray bursts (GRBs) are an extremely rare outcome of the collapse of massive stars and are typically found in the distant universe. Because of its intrinsic luminosity (L ~ 3 × 10(53) ergs per second) and its relative proximity (z = 0.34), GRB 130427A reached the highest fluence observed in the γ-ray band. Here, we present a comprehensive multiwavelength view of GRB 130427A with Swift, the 2-meter Liverpool and Faulkes telescopes, and by other ground-based facilities, highlighting the evolution of the burst emission from the prompt to the afterglow phase. The properties of GRB 130427A are similar to those of the most luminous, high-redshift GRBs, suggesting that a common central engine is responsible for producing GRBs in both the contemporary and the early universe and over the full range of GRB isotropic energies.

Galaxy evolution in clusters since z=1

NASA Astrophysics Data System (ADS)

Aragón-Salamanca, A.

2011-11-01

It is now 30 years since Alan Dressler published his seminal paper onthe morphology-density relation. Although there is still much to learnon the effect of the environment on galaxy evolution, extensive progress has been made since then both observationally and theoretically.Galaxy clusters provide some of the most extreme environments in which galaxies evolve, making them excellent laboratories to study the age old question of "nature'' vs. "nurture'' in galaxy evolution. Here I review some of the key observational results obtained during the last decade on the evolution of the morphology, structure, dynamics, star-formation history and stellar populations of cluster galaxies since the time when the universe was half its present age.Many of the results presented here have been obtainedwithin the ESO Distant Cluster Survey (EDisCS) and Space Telescope A901/02 Galaxy Evolution Survey (STAGES) collaborations.

Discovery of extreme [O III] λ5007 Å outflows in high-redshift red quasars

NASA Astrophysics Data System (ADS)

Zakamska, Nadia L.; Hamann, Fred; Pâris, Isabelle; Brandt, W. N.; Greene, Jenny E.; Strauss, Michael A.; Villforth, Carolin; Wylezalek, Dominika; Alexandroff, Rachael M.; Ross, Nicholas P.

2016-07-01

Black hole feedback is now a standard component of galaxy formation models. These models predict that the impact of black hole activity on its host galaxy likely peaked at z = 2-3, the epoch of strongest star formation activity and black hole accretion activity in the Universe. We used XSHOOTER on the Very Large Telescope to measure rest-frame optical spectra of four z ˜ 2.5 extremely red quasars with infrared luminosities ˜1047 erg s-1. We present the discovery of very broad (full width at half max = 2600-5000 km s-1), strongly blueshifted (by up to 1500 km s-1) [O III] λ5007 Å emission lines in these objects. In a large sample of type 2 and red quasars, [O III] kinematics are positively correlated with infrared luminosity, and the four objects in our sample are on the extreme end in both [O III] kinematics and infrared luminosity. We estimate that at least 3 per cent of the bolometric luminosity in these objects is being converted into the kinetic power of the observed wind. Photo-ionization estimates suggest that the [O III] emission might be extended on a few kpc scales, which would suggest that the extreme outflow is affecting the entire host galaxy of the quasar. These sources may be the signposts of the most extreme form of quasar feedback at the peak epoch of galaxy formation, and may represent an active `blow-out' phase of quasar evolution.

Analysis and evaluation of functional status of lower extremity amputee-appliance systems: an integrated approach.

PubMed

Ganguli, S

1976-11-01

This paper introduces an integrated, objective and biomechanically sound approach for the analysis and evaluation of the functional status of lower extremity amputee-appliance systems. The method is demonstrated here in its application to the unilateral lower extremity amputee-axillary crutches system and the unilateral below-knee amputee-PTB prosthesis system, both of which are commonly encountered in day-to-day rehabilitation practice.

The Diffuse X-ray Background, from Earth's Exosphere to the Edge of the Universe: Or, One Astronomer's Signal is Another Astronomer's Contamination

NASA Technical Reports Server (NTRS)

Snowden, Steve

2007-01-01

The "X-ray background" means various things to various people. It's origin is comprised of emission from objects as close as Earth's exosphere to as far away as the most distant clusters of galaxies. It is comprised of the emission of truly diffusely distributed plasmas and the superposition of the emission from unresolved point-like objects. To add to the confusion, in general there is no redshift information so there is very little information on where an individual X-ray may originate. This talk will address the evolution of our understanding of origin of the X-ray background and the current best-guess about what is really going on.

Comet C/2017 K2 (PANSTARRS): Dynamically Old or New?

NASA Astrophysics Data System (ADS)

de la Fuente Marcos, Raúl; de la Fuente Marcos, Carlos

2018-04-01

At discovery time, C/2017 K2 (PANSTARRS) was the second most distant inbound active comet ever observed. It has been argued that this object is in the process of crossing the inner Solar System for the first time, but other authors have concluded that it is dynamically old. We have performed full N-body simulations for 3 Myr into the past using the latest public orbit determination for this object and most of them, 67%, are consistent with a bound and dynamically old Oort cloud comet, but about 29% of the studied orbits are compatible with an interstellar origin. Our independent calculations strongly suggest that C/2017 K2 is not a dynamically new Oort cloud comet.

Wave optics of the central spot in planetary occultations

NASA Technical Reports Server (NTRS)

Hubbard, W. B.

1977-01-01

The detection of a bright central spot during the occultation of epsilon Geminorum by Mars demonstrates that an exponentially-stratified planetary atmosphere can act as a lens providing very high resolution of distant objects (e.g., quasars, white dwarfs, and pulsars). The diffraction nature of the central occultation spot is investigated, with special reference to Mars and Venus. In practice, however, central occultations by these planets are seldom observable from the earth's surface, and spacecraft would have to be used to obtain a suitable orientation for observers. Further difficulties may be encountered in image deconvolution needed for extended objects, in location of the image of a true point source, and in compensation for peculiarities of planets and their atmospheres.

KSC-99pp1058

NASA Image and Video Library

1999-08-19

STS-93 Pilot Jeffrey S. Ashby signs autographs after a mission presentation for KSC employees. The five-day mission primarily released the Chandra X-ray Observatory, allowing scientists from around the world to study some of the most distant, powerful and dynamic objects in the universe. Chandra is expected to provide unique and crucial information on the nature of objects ranging from comets in our solar system to quasars at the edge of the observable universe. Since X-rays are absorbed by the Earth's atmosphere, space-based observatories are necessary to study these phenomena and allow scientists to analyze some of the greatest mysteries of the universe. STS-93 was also the first mission to have a woman, Eileen M. Collins, serving as Shuttle commander

Astronomers Discover Six-Image Gravitational Lens

NASA Astrophysics Data System (ADS)

2001-08-01

An international team of astronomers has used the National Science Foundation's Very Long Baseline Array (VLBA) radio telescope and NASA's Hubble Space Telescope (HST) to discover the first gravitational lens in which the single image of a very distant galaxy has been split into six different images. The unique configuration is produced by the gravitational effect of three galaxies along the line of sight between the more-distant galaxy and Earth. Optical and Radio Images of Gravitational Lens "This is the first gravitational lens with more than four images of the background object that is produced by a small group of galaxies rather than a large cluster of galaxies," said David Rusin, who just received his Ph.D. from the University of Pennsylvania. "Such systems are expected to be extremely rare, so this discovery is an important stepping stone. Because this is an intermediate case between gravitational lenses produced by single galaxies and lenses produced by large clusters of galaxies, it will give us insights we can't get from other types of lenses," Rusin added. The gravitational lens, called CLASS B1359+154, consists of a galaxy more than 11 billion light-years away in the constellation Bootes, with a trio of galaxies more than 7 billion light-years away along the same line of sight. The more-distant galaxy shows signs that it contains a massive black hole at its core and also has regions in which new stars are forming. The gravitational effect of the intervening galaxies has caused the light and radio waves from the single, more-distant galaxy to be "bent" to form six images as seen from Earth. Four of these images appear outside the triangle formed by the three intermediate galaxies and two appear inside that triangle. "This lens system is a very interesting case to study because it is more complicated than lenses produced by single galaxies, and yet simpler than lenses produced by clusters of numerous galaxies," said Chris Kochanek of the Harvard-Smithsonian Center for Astrophysics (CfA). "When we understand this system, we will have a much clearer picture of how galaxies are changed by being part of a bigger cluster of galaxies," he added. B1359+154 was discovered in 1999 by the Cosmic Lens All-Sky Survey, an international collaboration of astronomers who use radio telescopes to search the sky for gravitational lenses. Images made by the NSF's Very Large Array in New Mexico and by Britain's MERLIN radio telescope showed six objects suspected of being gravitational-lens images, but the results were inconclusive. Rusin and his team used the VLBA and HST in 1999 and 2000 to make more-detailed studies of B1359+154. The combination of data from the VLBA and HST convinced the astronomers that B1359+154 actually consists of six lensed images of a single background galaxy. The VLBA images were made from data collected during observations at a radio frequency of 1.7 GHz. "This is a great example of modern, multi-wavelength astronomy," said Rusin. "We need the radio telescopes to detect the gravitational lenses in the first place, then we need the visible-light information from Hubble to show us additional detail about the structure of the system." Armed with the combined VLBA and HST data about the positions and brightnesses of the six images of the background galaxy as well as the positions of the three intermediate galaxies, the astronomers did computer simulations to show how the gravitation of the three galaxies could produce the lens effect. They were able to design a computer model of the system that, in fact, produces the six images seen in B1359+154. "Our computer model certainly is not perfect, and we need to do more observations of this system to refine it, but we have clearly demonstrated that the three galaxies we see can produce a six-image lens system," said Martin Norbury, a graduate student at Jodrell Bank Observatory in Britain. "We think this work will give us an excellent tool for studying much-denser clusters of galaxies and the relationships of the individual cluster galaxies to the 'halo' of dark matter in which they are embedded," he added. Clusters of galaxies are known to produce gravitational lenses with up to eight images of a single background object. However, the number of galaxies in such a cluster makes it difficult for astronomers to decipher just how their gravitational effects have combined to produce the multiple images. Researchers hope to be able to understand the lensing effect well enough to use the lenses to show them how galaxies, gas and unseen dark matter in clusters are distributed. A system such as B1359+154, with only three galaxies involved in the lensing, can help astronomers learn how complex gravitational lenses work. "The next big step is to use HST to see the pattern of rings produced by the galaxy surrounding the black hole. We already see hints of them, but with the upgrades to HST in the next servicing mission we should be able to trace it completely both to pin down the structure of the lens and to have an enormously magnified image for studying the distant host galaxy," Kochanek said. In addition to Rusin, Kochanek and Norbury, the researchers are: Emilio Falco of the CfA; Chris Impey of Steward Observatory at the University of Arizona; Joseph Lehar of the CfA; Brian McLeod of the CfA; Hans-Walter Rix of the Max Planck Institute for Astronomy in Germany; Chuck Keeton of Steward Observatory; Jose Munoz of the Astrophysical Institute of the Canaries in Tenerife, Spain; and Chien Peng of Steward Observatory. The team published its results in the Astrophysical Journal. The VLBA is a system of 10 radio-telescope antennas that work together as a single astronomical instrument. The antennas are spread across the United States, from Hawaii in the west to the U.S. Virgin Islands in the east. A radio telescope system more than 5,000 miles across, the VLBA produces extremely detailed images. The National Radio Astronomy Observatory is a facility of the National Science Foundation, operated under cooperative agreement by Associated Universities, Inc. The Space Telescope Science Institute is operated by the Association of Universities for Research in Astronomy, Inc., for NASA,, under contract with the Goddard Space Flight Center, Greenbelt, MD. The Hubble Space Telescope is a project of international Cooperation between NASA and the European Space Agency.

Primary results from the Pan-STARRS-1 Outer Solar System Key Project

NASA Astrophysics Data System (ADS)

Holman, Matthew J.; Chen, Ying-Tung; Lackner, Michael; Payne, Matthew John; Lin, Hsing-Wen; Cristopher Fraser, Wesley; Lacerda, Pedro; Pan-STARRS 1 Science Consortium

2016-10-01

We have completed a search for slow moving bodies in the data obtained by the Pan-STARRS-1 (PS1) Science Consortium from 2010 to 2014. The data set covers the full sky north of -30 degrees declination, in the PS1 g, r, i, z, y, and w (g+r+i) filters. Our novel distance-based search is effective at detecting and linking very slow moving objects with sparsely sampled observations, even if observations are widely separated in RA, Dec and time, which is relevant to the future LSST solar system searches. In particular, our search is sensitive to objects at heliocentric distances of 25-2000 AU with magnitudes brighter than approximately r=22.5, without limits on the inclination of the object. We recover hundreds of known TNOs and Centaurs and discover hundreds of new objects, measuring phase and color information for many of them. Other highlights include the discovery of a second retrograde TNO, a number of Neptune Trojans, and large numbers of distant resonant TNOs.

NIR Spectroscopic Observation of Massive Galaxies in the Protocluster at z = 3.09

NASA Astrophysics Data System (ADS)

Kubo, Mariko; Yamada, Toru; Ichikawa, Takashi; Kajisawa, Masaru; Matsuda, Yuichi; Tanaka, Ichi

2015-01-01

We present the results of near-infrared spectroscopic observations of the K-band-selected candidate galaxies in the protocluster at z = 3.09 in the SSA22 field. We observed 67 candidates with K AB < 24 and confirmed redshifts of the 39 galaxies at 2.0 < z spec < 3.4. Of the 67 candidates, 24 are certainly protocluster members with 3.04 <= z spec <= 3.12, which are massive red galaxies that have been unidentified in previous optical observations of the SSA22 protocluster. Many distant red galaxies (J - K AB > 1.4), hyper extremely red objects (J - K AB > 2.1), Spitzer MIPS 24 μm sources, active galactic nuclei (AGNs) as well as the counterparts of Lyα blobs and the AzTEC/ASTE 1.1 mm sources in the SSA22 field are also found to be protocluster members. The mass of the SSA22 protocluster is estimated to be ~2-5 × 1014 M ⊙, and this system is plausibly a progenitor of the most massive clusters of galaxies in the current universe. The reddest (J - K AB >= 2.4) protocluster galaxies are massive galaxies with M star ~ 1011 M ⊙ showing quiescent star formation activities and plausibly dominated by old stellar populations. Most of these massive quiescent galaxies host moderately luminous AGNs detected by X-ray. There are no significant differences in the [O III] λ5007/Hβ emission line ratios and [O III] λ5007 line widths and spatial extents of the protocluster galaxies from those of massive galaxies at z ~ 2-3 in the general field.

Galaxy Evolution in the Reddest Possible Filter

NASA Astrophysics Data System (ADS)

Richards, E. A.

We describe an observational programme aimed at understanding the radio emission from distant, rapidly evolving galaxy populations. These observations were carried out at 1.4 and 8.5 GHz with the VLA, centred on the Hubble Deep Field, obtaining limiting flux densities of 40 and 8 μJy respectively. The differential count of the radio sources is marginally sub-Euclidean to the completeness limits (γ = - 2.4 +/- 0.1) and fluctuation analysis suggests nearly 60 sources per arcmin^2 at the 1 μJy level. Using high-resolution 1.4 GHz observations obtained with MERLIN, we resolve all radio sources detected in the VLA complete sample and measure a median angular size for the microjansky radio population of 1-2``. This clue, coupled with the steep spectral index of the 1.4 GHz selected sample, suggests diffuse synchrotron radiation in z ~ 1 galactic discs. The wide-field HST and ground-based optical exposures show that the radio sources are identified primarily with disc systems composed of irregulars, peculiars, interacting/merging galaxies and a few isolated field spirals. Only 20% of the radio sources can be attributed to AGN - the majority are probably associated with starburst activity. The available redshifts range from 0.1 to 3, with a mean of about 0.8. We are plrobably witnessing a major episode of starburst activity in these luminous (L > L_*) systems, occasionally accompanied by an embedded AGN. About 20% of the radio sources remain unidentified to I = 26-28 in the HDF and flanking fields. Several of these objects have extremely red counterparts. We suggest that these are high-redshift dusty protogalaxies.

Spitzer SAGE-Spec: Near infrared spectroscopy, dust shells, and cool envelopes in extreme Large Magellanic Cloud asymptotic giant branch stars

DOE Office of Scientific and Technical Information (OSTI.GOV)

Blum, R. D.; Srinivasan, S.; Kemper, F.

2014-11-01

K-band spectra are presented for a sample of 39 Spitzer Infrared Spectrograph (IRS) SAGE-Spec sources in the Large Magellanic Cloud. The spectra exhibit characteristics in very good agreement with their positions in the near-infrared—Spitzer color-magnitude diagrams and their properties as deduced from the Spitzer IRS spectra. Specifically, the near-infrared spectra show strong atomic and molecular features representative of oxygen-rich and carbon-rich asymptotic giant branch stars, respectively. A small subset of stars was chosen from the luminous and red extreme ''tip'' of the color-magnitude diagram. These objects have properties consistent with dusty envelopes but also cool, carbon-rich ''stellar'' cores. Modest amountsmore » of dust mass loss combine with the stellar spectral energy distribution to make these objects appear extreme in their near-infrared and mid-infrared colors. One object in our sample, HV 915, a known post-asymptotic giant branch star of the RV Tau type, exhibits CO 2.3 μm band head emission consistent with previous work that demonstrates that the object has a circumstellar disk.« less

Balloon-borne three-meter telescope for far-infrared and submillimeter astronomy

NASA Technical Reports Server (NTRS)

Fazio, G. G.

1985-01-01

Presented are scientific objectives, engineering analysis and design, and results of technology development for a Three-Meter Balloon-Borne Far-Infrared and Submillimeter Telescope. The scientific rationale is based on two crucial instrumental capabilities: high angular resolution which approaches eight arcseconds at one hundred micron wavelength, and high resolving power spectroscopy with good sensitivity throughout the telescope's 30-micron to 1-mm wavelength range. The high angular resolution will allow us to resolve and study in detail such objects as collapsing protostellar condensations in our own galaxy, clusters of protostars in the Magellanic clouds, giant molecular clouds in nearby galaxies, and spiral arms in distant galaxies. The large aperture of the telescope will permit sensitive spectral line measurements of molecules, atoms, and ions, which can be used to probe the physical, chemical, and dynamical conditions in a wide variety of objects.

The Wealth of the Body: Trade Relations, Objects, and Personhood in Northeastern Amazonia

PubMed Central

Grotti, Vanessa

2016-01-01

This article is an analysis of trade among the Trio (Suriname), and their relationship with objects and persons in their quest for manufactured goods. Based on data mostly collected in the Trio village of Tëpu in southern Suriname, it discusses trade from the point of view of Amerindian sociality, with regard to the nature of the interpersonal relations involved. I examine trade through the prism of an Amerindian understanding of personhood, the body and materiality, and show how these relationships tend to be fabricated over a lifetime, eventually becoming an integral and material part of the actors involved. This is manifested in the way Trio social space is constructed and inhabited as an extension of the body, and how objects acquired through trade come to elicit narratives of past exploits and travels to distant spheres of alterity. [Brazil, Guyana, indigenous people, social anthropology, Surinam] PMID:27175223

Relative Positions of Distant Spacecraft

NASA Image and Video Library

2011-04-29

This graphic shows the relative positions of NASA most distant spacecraft in early 2011, looking at the solar system from the side. Voyager 1 is the most distant spacecraft, 10.9 billion miles away from the sun at a northward angle.

We Detected Phenomena, Like Africa's Dogon, that Speak of Stellar Gravitational Neutrino Interactions

NASA Astrophysics Data System (ADS)

McLeod, David Matthew; McLeod, Roger David

2009-05-01

Stick figure equivalents of Kokopelli/Pele/Pamola/Thor/Orion/Osiris, Canis Major/Anubis/Wolf/Fox, Leo/Bird Tailed Jaguar/Beaver Tailed Mountain Lion, were detected by us. They figure heavily in the spiritual/scientific world view of many traditional societies, and their cultural respect for the information such figures convey. Scientific instruments from the past were our laboratories, and theirs. All string/stick figure equivalents may represent types of longitudinally aligned neutrino flux between certain stellar pairs. Neutrino beams from distant pulsars, quasars, or other neutrino sources, cannot penetrate these graviton-like strings. They do pass through sectors of Earth, projecting stick figures within instruments like the Watch House at America's Stonehenge, and perhaps the chamber beneath the Great Pyramid. Sirius B, as the heaviest object in ``our'' universe for the Dogon, means it shares a profound graviton-like neutrino highway to our sun, as Sirius B/A do within Canis Major. It is possibly projected by a source within the Canis Major dwarf galaxy at about 3,000 times as distant as Sirius B/A at 8.7 ly.

Differences in self-reported physical limitation among older women and men in Ismailia, Egypt.

PubMed

Khadr, Zeinab; Yount, Kathryn

2012-09-01

This study explores the reasons for gender differences in self-reported physical limitation among older adults in Ismailia, Egypt. 435 women and 448 men, 50 years and older in Ismailia, Egypt, participated in a social survey and tests of physical performance. Ordered logit models were estimated to compare unadjusted gender differences in reported disability with these differences adjusted sequentially for (a) age and objective measures of physical performance, (b) self-reported morbidities and health care use, and (c) social and economic attributes. Compared with men, women more often reported higher levels of limitation in activities of daily living (ADLs), upper-extremity range of motion (ROM), and lower-extremity gross mobility (GM). Adjusting for age and objective measures of physical performance, women and men had similar odds of self-reporting difficulty with ADLs. With sequential adjustments for the remaining variables, women maintained significantly higher odds of self-reported difficulty with upper-extremity ROM and lower-extremity GM. Cross-culturally, gender differences in self-reported disability may arise from objective and subjective perceptions of disability. Collectively, these results and those from prior studies in Bangladesh and the United States suggest that gender gaps in self-reported physical limitation may be associated with the degree of gender equality in society.

A pilot study of physiological reactivity in children and maternal figures who lost relatives in a terrorist attack.

PubMed

Pfefferbaum, Betty; Tucker, Phebe; Jeon-Slaughter, Haekyung; Allen, James R; Hammond, Donna R; Whittlesey, Suzanne W; Vinekar, Shreekumar S; Feng, Yan

2013-01-01

Trauma is thought to interfere with normal grief by superimposing symptoms of posttraumatic stress disorder. This exploratory pilot study examined the association between traumatic grief and objectively measured physiological reactivity to a trauma interview in 73 children who lost relatives in the Oklahoma City bombing as well as a potential link between children and their maternal figures in physiological reactivity. Although the authors found no association between posttraumatic stress and objectively measured physiological reactivity among children, they found significant differences in objectively measured reactivity associated with loss and grief. Children who lost "close" relatives evidenced greater objectively measured reactivity than those who lost "distant" relatives. For the most part, children with higher levels of grief evidenced greater objectively measured reactivity than those with lower levels of grief. The most interesting of the findings was the parallel pattern in objectively measured physiological reactivity between children and their maternal figures along with a positive association between children's objectively measured physiological reactivity and maternal figures' self-reported physiological reactivity. Research using larger representative samples studied early and over time is indicated to determine the potential significance of these findings.

Behind the Periscope: Leadership in China’s Navy

DTIC Science & Technology

2013-12-01

Spring Festival Distant Sea Voyage: A Complete Account of the North Sea Fleet’s Distant Seas Training Vessel Formation” (zhongguo haijun de ‘chunjie...staff VADM Du Jingchen.596 During the expedition, Yin convened a political working group which created a musical piece called “Song of the Gulf of Aden...Spring Festival Distant Sea Voyage: A Complete Account of the North Sea Fleet’s Distant Seas Training Vessel Formation” (zhongguo haijun de ‘chunjie

Frequency and Correlates of Distant Visual Impairment in Patients with Schizophrenia, Bipolar Disorder, and Major Depressive Disorder.

PubMed

Zheng, W; Tang, L R; Correll, C U; Ungvari, G S; Chiu, H F K; Xiang, Y Q; Xiang, Y T

2015-09-01

Distant visual impairment in the severely mentally ill is under-researched. This study aimed to assess the frequency and correlates of distant visual impairment in a cohort of Chinese psychiatric patients, including its effect on their quality of life. Adult psychiatric inpatients with schizophrenia, bipolar disorder, and major depressive disorder consecutively admitted to a psychiatric hospital in Beijing, China underwent assessments of psychopathology (Brief Psychiatric Rating Scale, 16-item Quick Inventory of Depressive Symptomatology [Self-Report]), quality of life (12-item Short-Form Medical Outcomes Study [SF-12], 25-item National Eye Institute Visual Function Questionnaire [NEI-VFQ25]), adverse effects (Udvalg for Kliniske Undersøgelser Side Effect Rating Scale), and presenting (as opposed to uncorrected) distant visual acuity (Logarithm of the Minimum Angle of Resolution [LogMAR] chart with patients wearing spectacles, if they owned them). Distant visual impairment was defined as binocular distant visual acuity of a LogMAR score of ≥ 0.5 (< 6/18 Snellen acuity). Among 356 patients who met the study criteria, the frequency of distant visual impairment was 12.6% (15.2% with schizophrenia, 11.9% with bipolar disorder, 8.8% with major depressive disorder). In multiple logistic regression analysis, distant visual impairment was significantly associated with ocular disease only (p = 0.002, odds ratio = 3.2, 95% confidence interval = 1.5-6.7). Controlling for the confounding effect of ocular disease, patients with distant visual impairment had a lower quality of life in the general vision domain of the NEI-VFQ25 (F[2, 353] = 9.5, p = 0.002) compared with those without. No differences in the physical and mental domains of the SF-12 and in other domains of the NEI-VFQ25 were noted in these 2 groups. One-eighth of middle-aged severely mentally ill patients had distant visual impairment. Considering the impact of distant visual impairment on daily functioning, severely mentally ill patients need to be screened for impaired eyesight as part of their comprehensive health assessment.

DUSTiNGS. III. Distribution of Intermediate-age and Old Stellar Populations in Disks and Outer Extremities of Dwarf Galaxies

NASA Astrophysics Data System (ADS)

McQuinn, Kristen B. W.; Boyer, Martha L.; Mitchell, Mallory B.; Skillman, Evan D.; Gehrz, R. D.; Groenewegen, Martin A. T.; McDonald, Iain; Sloan, G. C.; van Loon, Jacco Th.; Whitelock, Patricia A.; Zijlstra, Albert A.

2017-01-01

We have traced the spatial distributions of intermediate-age and old stars in nine dwarf galaxies in the distant parts of the Local Group, using multi-epoch 3.6 and 4.5 μm data from the DUST in Nearby Galaxies with Spitzer (DUSTiNGS) survey. Using complementary optical imaging from the Hubble Space Telescope, we identify the tip of the red giant branch (TRGB) in the 3.6 μm photometry, separating thermally pulsating asymptotic giant branch stars from the larger red giant branch populations. Unlike the constant TRGB in the I band, at 3.6 μm, the TRGB magnitude varies by ˜0.7 mag, making it unreliable as a distance indicator. The intermediate-age and old stars are well mixed in two-thirds of the sample, with no evidence of a gradient in the ratio of the intermediate-age to old stellar populations outside the central ˜1‧-2‧. Variable AGB stars are detected in the outer extremities of the galaxies, indicating that chemical enrichment from these dust-producing stars may occur in the outer regions of galaxies with some frequency. Theories of structure formation in dwarf galaxies must account for the lack of radial gradients in intermediate-age populations and the presence of these stars in the outer extremities of dwarfs. Finally, we identify unique features in individual galaxies, such as extended tidal features in Sex A and Sag DIG and a central concentration of AGB stars in the inner regions of NGC 185 and NGC 147.

Complete genome sequence of 'Halanaeroarchaeum sulfurireducens' M27-SA2, a sulfur-reducing and acetate-oxidizing haloarchaeon from the deep-sea hypersaline anoxic lake Medee.

PubMed

Messina, Enzo; Sorokin, Dimitry Y; Kublanov, Ilya V; Toshchakov, Stepan; Lopatina, Anna; Arcadi, Erika; Smedile, Francesco; La Spada, Gina; La Cono, Violetta; Yakimov, Michail M

2016-01-01

Strain M27-SA2 was isolated from the deep-sea salt-saturated anoxic lake Medee, which represents one of the most hostile extreme environments on our planet. On the basis of physiological studies and phylogenetic positioning this extremely halophilic euryarchaeon belongs to a novel genus 'Halanaeroarchaeum' within the family Halobacteriaceae. All members of this genus cultivated so far are strict anaerobes using acetate as the sole carbon and energy source and elemental sulfur as electron acceptor. Here we report the complete genome sequence of the strain M27-SA2 which is composed of a 2,129,244-bp chromosome and a 124,256-bp plasmid. This is the second complete genome sequence within the genus Halanaeroarchaeum. We demonstrate that genome of 'Halanaeroarchaeum sulfurireducens' M27-SA2 harbors complete metabolic pathways for acetate and sulfur catabolism and for de novo biosynthesis of 19 amino acids. The genomic analysis also reveals that 'Halanaeroarchaeum sulfurireducens' M27-SA2 harbors two prophage loci and one CRISPR locus, highly similar to that of Kulunda Steppe (Altai, Russia) isolate 'H. sulfurireducens' HSR2(T). The discovery of sulfur-respiring acetate-utilizing haloarchaeon in deep-sea hypersaline anoxic lakes has certain significance for understanding the biogeochemical functioning of these harsh ecosystems, which are incompatible with life for common organisms. Moreover, isolations of Halanaeroarchaeum members from geographically distant salt-saturated sites of different origin suggest a high degree of evolutionary success in their adaptation to this type of extreme biotopes around the world.

Evaluation of teleoperated surgical robots in an enclosed undersea environment.

PubMed

Doarn, Charles R; Anvari, Mehran; Low, Thomas; Broderick, Timothy J

2009-05-01

The ability to support surgical care in an extreme environment is a significant issue for both military medicine and space medicine. Telemanipulation systems, those that can be remotely operated from a distant site, have been used extensively by the National Aeronautics and Space Administration (NASA) for a number of years. These systems, often called telerobots, have successfully been applied to surgical interventions. A further extension is to operate these robotic systems over data communication networks where robotic slave and master are separated by a great distance. NASA utilizes the National Oceanographic and Atmospheric Administration (NOAA) Aquarius underwater habitat as an analog environment for research and technology evaluation missions, known as NASA Extreme Environment Mission Operations (NEEMO). Three NEEMO missions have provided an opportunity to evaluate teleoperated surgical robotics by astronauts and surgeons. Three robotic systems were deployed to the habitat for evaluation during NEEMO 7, 9, and 12. These systems were linked via a telecommunications link to various sites for remote manipulation. Researchers in the habitat conducted a variety of tests to evaluate performance and applicability in extreme environments. Over three different NEEMO missions, components of the Automated Endoscopic System for Optimal Positioning (AESOP), the M7 Surgical System, and the RAVEN were deployed and evaluated. A number of factors were evaluated, including communication latency and semiautonomous functions. The M7 was modified to permit a remote surgeon the ability to insert a needle into simulated tissue with ultrasound guidance, resulting in the world's first semi-autonomous supervisory-controlled medical task. The deployment and operation of teleoperated surgical systems and semi-autonomous, supervisory-controlled tasks were successfully conducted.

Asteroid-comet continuum objects in the solar system.

PubMed

Hsieh, Henry H

2017-07-13

In this review presented at the Royal Society meeting, 'Cometary science after Rosetta', I present an overview of studies of small solar system objects that exhibit properties of both asteroids and comets (with a focus on so-called active asteroids). Sometimes referred to as 'transition objects', these bodies are perhaps more appropriately described as 'continuum objects', to reflect the notion that rather than necessarily representing actual transitional evolutionary states between asteroids and comets, they simply belong to the general population of small solar system bodies that happen to exhibit a continuous range of observational, physical and dynamical properties. Continuum objects are intriguing because they possess many of the properties that make classical comets interesting to study (e.g. relatively primitive compositions, ejection of surface and subsurface material into space where it can be more easily studied, and orbital properties that allow us to sample material from distant parts of the solar system that would otherwise be inaccessible), while allowing us to study regions of the solar system that are not sampled by classical comets.This article is part of the themed issue 'Cometary science after Rosetta'. © 2017 The Author(s).

Secular Extragalactic Parallax and Geometric Distances with Gaia Proper Motions

NASA Astrophysics Data System (ADS)

Paine, Jennie; Darling, Jeremiah K.

2018-06-01

The motion of the Solar System with respect to the cosmic microwave background (CMB) rest frame creates a well measured dipole in the CMB, which corresponds to a linear solar velocity of about 78 AU/yr. This motion causes relatively nearby extragalactic objects to appear to move compared to more distant objects, an effect that can be measured in the proper motions of nearby galaxies. An object at 1 Mpc and perpendicular to the CMB apex will exhibit a secular parallax, observed as a proper motion, of 78 µas/yr. The relatively large peculiar motions of galaxies make the detection of secular parallax challenging for individual objects. Instead, a statistical parallax measurement can be made for a sample of objects with proper motions, where the global parallax signal is modeled as an E-mode dipole that diminishes linearly with distance. We present preliminary results of applying this model to a sample of nearby galaxies with Gaia proper motions to detect the statistical secular parallax signal. The statistical measurement can be used to calibrate the canonical cosmological “distance ladder.”

Gamma watermarking

DOEpatents

Ishikawa, Muriel Y.; Wood, Lowell L.; Lougheed, Ronald W.; Moody, Kenton J.; Wang, Tzu-Fang

2004-05-25

A covert, gamma-ray "signature" is used as a "watermark" for property identification. This new watermarking technology is based on a unique steganographic or "hidden writing" digital signature, implemented in tiny quantities of gamma-ray-emitting radioisotopic material combinations, generally covertly emplaced on or within an object. This digital signature may be readily recovered at distant future times, by placing a sensitive, high energy-resolution gamma-ray detecting instrument reasonably precisely over the location of the watermark, which location may be known only to the object's owner; however, the signature is concealed from all ordinary detection means because its exceedingly low level of activity is obscured by the natural radiation background (including the gamma radiation naturally emanating from the object itself, from cosmic radiation and material surroundings, from human bodies, etc.). The "watermark" is used in object-tagging for establishing object identity, history or ownership. It thus may serve as an aid to law enforcement officials in identifying stolen property and prosecuting theft thereof. Highly effective, potentially very low cost identification-on demand of items of most all types is thus made possible.

Lightning Sensors for Observing, Tracking and Nowcasting Severe Weather

PubMed Central

Price, Colin

2008-01-01

Severe and extreme weather is a major natural hazard all over the world, often resulting in major natural disasters such as hail storms, tornados, wind storms, flash floods, forest fires and lightning damages. While precipitation, wind, hail, tornados, turbulence, etc. can only be observed at close distances, lightning activity in these damaging storms can be monitored at all spatial scales, from local (using very high frequency [VHF] sensors), to regional (using very low frequency [VLF] sensors), and even global scales (using extremely low frequency [ELF] sensors). Using sensors that detect the radio waves emitted by each lightning discharge, it is now possible to observe and track continuously distant thunderstorms using ground networks of sensors. In addition to the number of lightning discharges, these sensors can also provide information on lightning characteristics such as the ratio between intra-cloud and cloud-to-ground lightning, the polarity of the lightning discharge, peak currents, charge removal, etc. It has been shown that changes in some of these lightning characteristics during thunderstorms are often related to changes in the severity of the storms. In this paper different lightning observing systems are described, and a few examples are provided showing how lightning may be used to monitor storm hazards around the globe, while also providing the possibility of supplying short term forecasts, called nowcasting. PMID:27879700

Ecogeography and utility to plant breeding of the crop wild relatives of sunflower (Helianthus annuus L.)

PubMed Central

Kantar, Michael B.; Sosa, Chrystian C.; Khoury, Colin K.; Castañeda-Álvarez, Nora P.; Achicanoy, Harold A.; Bernau, Vivian; Kane, Nolan C.; Marek, Laura; Seiler, Gerald; Rieseberg, Loren H.

2015-01-01

Crop wild relatives (CWR) are a rich source of genetic diversity for crop improvement. Combining ecogeographic and phylogenetic techniques can inform both conservation and breeding. Geographic occurrence, bioclimatic, and biophysical data were used to predict species distributions, range overlap and niche occupancy in 36 taxa closely related to sunflower (Helianthus annuus L.). Taxa lacking comprehensive ex situ conservation were identified. The predicted distributions for 36 Helianthus taxa identified substantial range overlap, range asymmetry and niche conservatism. Specific taxa (e.g., Helianthus deblis Nutt., Helianthus anomalus Blake, and Helianthus divaricatus L.) were identified as targets for traits of interest, particularly for abiotic stress tolerance, and adaptation to extreme soil properties. The combination of techniques demonstrates the potential for publicly available ecogeographic and phylogenetic data to facilitate the identification of possible sources of abiotic stress traits for plant breeding programs. Much of the primary genepool (wild H. annuus) occurs in extreme environments indicating that introgression of targeted traits may be relatively straightforward. Sister taxa in Helianthus have greater range overlap than more distantly related taxa within the genus. This adds to a growing body of literature suggesting that in plants (unlike some animal groups), geographic isolation may not be necessary for speciation. PMID:26500675

Ecogeography and utility to plant breeding of the crop wild relatives of sunflower (Helianthus annuus L.).

PubMed

Kantar, Michael B; Sosa, Chrystian C; Khoury, Colin K; Castañeda-Álvarez, Nora P; Achicanoy, Harold A; Bernau, Vivian; Kane, Nolan C; Marek, Laura; Seiler, Gerald; Rieseberg, Loren H

2015-01-01

Crop wild relatives (CWR) are a rich source of genetic diversity for crop improvement. Combining ecogeographic and phylogenetic techniques can inform both conservation and breeding. Geographic occurrence, bioclimatic, and biophysical data were used to predict species distributions, range overlap and niche occupancy in 36 taxa closely related to sunflower (Helianthus annuus L.). Taxa lacking comprehensive ex situ conservation were identified. The predicted distributions for 36 Helianthus taxa identified substantial range overlap, range asymmetry and niche conservatism. Specific taxa (e.g., Helianthus deblis Nutt., Helianthus anomalus Blake, and Helianthus divaricatus L.) were identified as targets for traits of interest, particularly for abiotic stress tolerance, and adaptation to extreme soil properties. The combination of techniques demonstrates the potential for publicly available ecogeographic and phylogenetic data to facilitate the identification of possible sources of abiotic stress traits for plant breeding programs. Much of the primary genepool (wild H. annuus) occurs in extreme environments indicating that introgression of targeted traits may be relatively straightforward. Sister taxa in Helianthus have greater range overlap than more distantly related taxa within the genus. This adds to a growing body of literature suggesting that in plants (unlike some animal groups), geographic isolation may not be necessary for speciation.

Primary Central Nervous System Fibrosarcoma.

PubMed

Vinodh, V P; Harun, Rahmat; Sellamuthu, Pulivendhan; Kandasamy, Regunath

2017-08-01

We report a rare case of a young female with primary brain fibrosarcoma, and to the best of our knowledge, we believe that only <50 cases have been reported or described worldwide so far. Fibrosarcoma is a malignant neoplasm, in which histologically the predominant cells are fibroblasts that divide excessively without cellular control and they can invade local tissues or metastasize. Primary central nervous system fibrosarcomas are very aggressive neoplasms and generally have a poor prognosis. This tumor is either from sarcomatous transformation of a meningioma or arises de novo within the brain parenchyma. Our patient, a 48-year-old woman, who presented with progressive speech disorder over the period of 4 months, showed a left temporoparietal lesion with surrounding edema and local mass effect. Total surgical resection was achieved. Histopathology revealed classical fibrosarcoma features and secondary screening revealed no other distant lesion as diagnosis of primary brain fibrosarcoma was established. This case is deemed to be extremely rare because most reports claim that recurrence is within 6 months with poor prognosis; however, this patient is currently recurrence-free at 3 years. This would suggest of the possibility for a relook into this disease's course and recurrence rate when complete excision is achieved. Due to extreme rarity of these tumors, more comparative studies will be needed to improve the disease outcome.

Predictors of false negative sentinel lymph node biopsy in trunk and extremity melanoma.

PubMed

Sinnamon, Andrew J; Neuwirth, Madalyn G; Bartlett, Edmund K; Zaheer, Salman; Etherington, Mark S; Xu, Xiaowei; Elder, David E; Czerniecki, Brian J; Fraker, Douglas L; Karakousis, Giorgos C

2017-12-01

Nodal recurrence following negative sentinel lymph node biopsy (SLNB) for melanoma is known as false-negative (FN) SLNB. Risk factors for FN SLNB among patients with trunk and extremity melanoma have not been well-defined. After retrospective review, SLNB procedures were classified FN, true positive (TP; positive SLNB), or true negative (TN; negative SLNB without recurrence). Factors associated with high false negative rate (FNR) and low negative predictive value (NPV) were identified by comparing FNs to TPs and TNs, respectively. Survival was evaluated using Kaplan-Meier methods. Of 1728 patients, 234 were TP and 37 were FN for overall FNR of 14% and NPV of 97.5%. Age ≥65 years was independently associated with high FNR (FNR 20% in this group). Breslow thickness >1 mm and ulceration were independently associated with low NPV. Among patients with ulcerated tumors >4 mm, NPV was 88%. Median time to recurrence for FNs was 13 months. Among patients with primary melanomas ≤2 mm in depth, overall and distant disease-free survival were significantly shorter with FN SLNB than TP SLNB. Older age is associated with increased FNR; patients with thick, ulcerated lesions should be considered for increased nodal surveillance after negative SLNB given low NPV in this group. © 2017 Wiley Periodicals, Inc.

Distance biases in the estimation of the physical properties of Hi-GAL compact sources - I. Clump properties and the identification of high-mass star-forming candidates

NASA Astrophysics Data System (ADS)

Baldeschi, Adriano; Elia, D.; Molinari, S.; Pezzuto, S.; Schisano, E.; Gatti, M.; Serra, A.; Merello, M.; Benedettini, M.; Di Giorgio, A. M.; Liu, J. S.

2017-04-01

The degradation of spatial resolution in star-forming regions, observed at large distances (d ≳ 1 kpc) with Herschel, can lead to estimates of the physical parameters of the detected compact sources (clumps), which do not necessarily mirror the properties of the original population of cores. This paper aims at quantifying the bias introduced in the estimation of these parameters by the distance effect. To do so, we consider Herschel maps of nearby star-forming regions taken from the Herschel Gould Belt survey, and simulate the effect of increased distance to understand what amount of information is lost when a distant star-forming region is observed with Herschel resolution. In the maps displaced to different distances we extract compact sources, and we derive their physical parameters as if they were original Herschel infrared Galactic Plane Survey maps of the extracted source samples. In this way, we are able to discuss how the main physical properties change with distance. In particular, we discuss the ability of clumps to form massive stars: we estimate the fraction of distant sources that are classified as high-mass stars-forming objects due to their position in the mass versus radius diagram, that are only 'false positives'. We also give a threshold for high-mass star formation M>1282 (r/ [pc])^{1.42} M_{⊙}. In conclusion, this paper provides the astronomer dealing with Herschel maps of distant star-forming regions with a set of prescriptions to partially recover the character of the core population in unresolved clumps.

Method and apparatus for determining return stroke polarity of distant lightning

NASA Technical Reports Server (NTRS)

Blakeslee, Richard J. (Inventor); Brook, Marx (Inventor)

1992-01-01

A method is described for determining the return stroke polarity of distant lightning for distances beyond 600 km by detecting the electric field associated with a return stroke of distant lightning, and processing the electric field signal to determine the polarity of the slow tail of the VLF waveform signal associated with the detected electric field. The polarity of the return stroke of distant lightning is determined based upon the polarity of the slow tail portion of the waveform.

Method and apparatus for determining return stroke polarity of distant lightning

NASA Technical Reports Server (NTRS)

Blakeslee, Richard J. (Inventor); Brook, Marx (Inventor)

1990-01-01

A method is described for determining the return stroke polarity of distant lightning for distances beyond 600 km by detecting the electric field associated with a return stroke of distant lightning, and processing the electric field signal to determine the polarity of the slow tail of the VLF waveform signal associated with the detected electric field. The polarity of the return stroke of distant lightning is determined based upon the polarity of the slow tail portion of the waveform.

Modelling Tradeoffs Evolution in Multipurpose Water Systems Operation in Response to Extreme Events

NASA Astrophysics Data System (ADS)

Mason, E.; Gazzotti, P.; Amigoni, F.; Giuliani, M.; Castelletti, A.

2015-12-01

Multipurpose water resource systems are usually operated on a tradeoff of the operating objectives, which - under steady state climatic and socio-economic boundary conditions - is supposed to ensure a fair and/or efficient balance among the conflicting interests. Extreme variability in the system's drivers might affect operators' risk aversion and force a change in the tradeoff. Properly accounting for these shifts is key to any rigorous retrospective assessment of operators' behavior and the associated system's performance. In this study, we explore how the selection of different optimal tradeoffs among the operating objectives is linked to the variations of the boundary conditions, such as, for example, drifting rainfall season or remarkable changes in crop and energy prices. We argue that tradeoff selection is driven by recent, extreme variations in system performance: underperforming on one of the operating objective target value should push the tradeoff toward the disadvantaged objective. To test this assumption, we developed a rational procedure to simulate the operators' tradeoff selection process. We map the selection onto a multi lateral negotiation process, where different multiple, virtual agents optimize different operating objectives. The agents periodically negotiate a compromise on the operating policy. The agent's rigidity in each negotiation round is determined by the recent system performances according to the specific objective it represents. The negotiation follows a set-based egocentric monotonic concession protocol: at each negotiation step an agent incrementally adds some options to the set of its acceptable compromises and (possibly) accepts lower and lower satisfying policies until an agreement is achieved. We apply this reiterated negotiation framework on the regulated Lake Como, Italy, simulating the lake dam operation and its recurrent updates over the last 50 years. The operation aims to balance shoreline flood prevention and irrigation deficit control in the downstream irrigated areas. The results of our simulated negotiations are able to accurately capture the operator's risk aversion changes as driven by extreme wet and dry situations, and to well reproduce the observational release data.

Regulated Extracellular Choline Acetyltransferase Activity— The Plausible Missing Link of the Distant Action of Acetylcholine in the Cholinergic Anti-Inflammatory Pathway

PubMed Central

Aeinehband, Shahin; Behbahani, Homira; Grandien, Alf; Nilsson, Bo; Ekdahl, Kristina N.; Lindblom, Rickard P. F.; Piehl, Fredrik; Darreh-Shori, Taher

2013-01-01

Acetylcholine (ACh), the classical neurotransmitter, also affects a variety of nonexcitable cells, such as endothelia, microglia, astrocytes and lymphocytes in both the nervous system and secondary lymphoid organs. Most of these cells are very distant from cholinergic synapses. The action of ACh on these distant cells is unlikely to occur through diffusion, given that ACh is very short-lived in the presence of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE), two extremely efficient ACh-degrading enzymes abundantly present in extracellular fluids. In this study, we show compelling evidence for presence of a high concentration and activity of the ACh-synthesizing enzyme, choline-acetyltransferase (ChAT) in human cerebrospinal fluid (CSF) and plasma. We show that ChAT levels are physiologically balanced to the levels of its counteracting enzymes, AChE and BuChE in the human plasma and CSF. Equilibrium analyses show that soluble ChAT maintains a steady-state ACh level in the presence of physiological levels of fully active ACh-degrading enzymes. We show that ChAT is secreted by cultured human-brain astrocytes, and that activated spleen lymphocytes release ChAT itself rather than ACh. We further report differential CSF levels of ChAT in relation to Alzheimer’s disease risk genotypes, as well as in patients with multiple sclerosis, a chronic neuroinflammatory disease, compared to controls. Interestingly, soluble CSF ChAT levels show strong correlation with soluble complement factor levels, supporting a role in inflammatory regulation. This study provides a plausible explanation for the long-distance action of ACh through continuous renewal of ACh in extracellular fluids by the soluble ChAT and thereby maintenance of steady-state equilibrium between hydrolysis and synthesis of this ubiquitous cholinergic signal substance in the brain and peripheral compartments. These findings may have important implications for the role of cholinergic signaling in states of inflammation in general and in neurodegenerative disease, such as Alzheimer’s disease and multiple sclerosis in particular. PMID:23840379

JPL's Role in Advancing Earth System Science to Meet the Challenges of Climate and Environmental Change

NASA Technical Reports Server (NTRS)

Evans, Diane

2012-01-01

Objective 2.1.1: Improve understanding of and improve the predictive capability for changes in the ozone layer, climate forcing, and air quality associated with changes in atmospheric composition. Objective 2.1.2: Enable improved predictive capability for weather and extreme weather events. Objective 2.1.3: Quantify, understand, and predict changes in Earth s ecosystems and biogeochemical cycles, including the global carbon cycle, land cover, and biodiversity. Objective 2.1.4: Quantify the key reservoirs and fluxes in the global water cycle and assess water cycle change and water quality. Objective 2.1.5: Improve understanding of the roles of the ocean, atmosphere, land and ice in the climate system and improve predictive capability for its future evolution. Objective 2.1.6: Characterize the dynamics of Earth s surface and interior and form the scientific basis for the assessment and mitigation of natural hazards and response to rare and extreme events. Objective 2.1.7: Enable the broad use of Earth system science observations and results in decision-making activities for societal benefits.

Scientists Celebrate VLBA's First Decade As Astronomy's Sharpest "Eye" on the Universe

NASA Astrophysics Data System (ADS)

2003-06-01

Scientists from around the globe are gathered in Socorro, New Mexico, to mark the tenth anniversary of the National Science Foundation's Very Long Baseline Array (VLBA) , a continent-wide radio telescope that produces the most detailed images of any instrument available to the world's astronomers. The VLBA The VLBA CREDIT: NRAO/AUI/NSF Nearly 200 scientists are presenting 160 research papers on topics including geophysics, star and planet formation, supernova explosions, galaxies, supermassive black holes, and future directions of research and instrumentation in astronomy. The meeting is sponsored by the National Radio Astronomy Observatory (NRAO) and the New Mexico Institute of Mining and Technology (NM Tech). The meeting is being held on the NM Tech campus in Socorro. "In ten years of operation, the VLBA has made landmark contributions to astronomy. In this scientific meeting, we are acknowledging those contributions and looking forward to an even more exciting future of frontier research," said James Ulvestad, director of VLA/VLBA operations for the NRAO. "The presentations at this meeting show that the VLBA is being used to study a much broader range of astronomical objects than was anticipated by its designers," said Prof. Roger Blandford of Caltech, who delivered the meeting's opening Keynote Address. Dedicated in 1993, the $85-million VLBA includes ten, 240-ton radio-telescope antennas, ranging from Hawaii in the west to the U.S. Virgin Islands in the east. Two are in New Mexico, one near Pie Town in Catron County and the other at Los Alamos. The VLBA is operated from the NRAO's Array Operations Center in Socorro. Acting like a giant eye 5,000 miles wide, the VLBA can produce the sharpest images of any telescope on Earth or in space. Its ability to see fine detail, called resolving power, is equivalent to being able to stand in New York and read a newspaper in Los Angeles. The VLBA's scientific achievements include making the most accurate distance measurement ever made of an object beyond the Milky Way Galaxy; the first mapping of the magnetic field of a star other than the Sun; "movies" of motions in powerful cosmic jets and of distant supernova explosions; the first measurement of the propagation speed of gravity; and long-term measurements that have improved the reference frame used to map the Universe and detect tectonic motions of Earth's continents. In coming years, scientists plan to use the VLBA, along with other radio-telescope facilities, to gain important new insights on astronomical bodies ranging from nearby stars to the most distant galaxies, seen as they were billions of years ago. The VLBA also will help improve the celestial coordinate system used for spacecraft navigation and other purposes. Blandford outlined a number of future research challenges, including understanding how pulsars produce their powerful beams of light and radio waves, learning how supermassive black holes and their nearby environments produce superfast cosmic jets, trying to understand solar bursts, using gravitational lenses to study the distant Universe, and understanding the mechanisms of gamma ray bursts and their "afterglows." "I am heartened to see the number of young astronomers at this meeting who are using the VLBA and will use it to help answer these important scientific questions," Blandford added. Closer to home, the VLBA can be "turned around" to produce extremely precise measurements on the Earth. This capability allows scientists to study the motion of Earth's tectonic plates, to track "wobbles" in our planet's rotation, and to measure subtle changes attributed to atmospheric motions and climate change. The meeting in Socorro began June 8 and runs through June 12. The National Radio Astronomy Observatory is a facility of the National Science Foundation, operated under cooperative agreement by Associated Universities, Inc.

Unveiling the nature of INTEGRAL objects through optical spectroscopy. IX. Twenty two more identifications, and a glance into the far hard X-ray Universe

NASA Astrophysics Data System (ADS)

Masetti, N.; Parisi, P.; Jiménez-Bailón, E.; Palazzi, E.; Chavushyan, V.; Bassani, L.; Bazzano, A.; Bird, A. J.; Dean, A. J.; Galaz, G.; Landi, R.; Malizia, A.; Minniti, D.; Morelli, L.; Schiavone, F.; Stephen, J. B.; Ubertini, P.

2012-02-01

Since its launch in October 2002, the INTEGRAL satellite has revolutionized our knowledge of the hard X-ray sky thanks to its unprecedented imaging capabilities and source detection positional accuracy above 20 keV. Nevertheless, many of the newly-detected sources in the INTEGRAL sky surveys are of unknown nature. The combined use of available information at longer wavelengths (mainly soft X-rays and radio) and of optical spectroscopy on the putative counterparts of these new hard X-ray objects allows us to pinpoint their exact nature. Continuing our long-standing program that has been running since 2004, and using 6 different telescopes of various sizes together with data from an online spectroscopic survey, here we report the classification through optical spectroscopy of 22 more unidentified or poorly studied high-energy sources detected with the IBIS instrument onboard INTEGRAL. We found that 16 of them are active galactic nuclei (AGNs), while the remaining 6 objects are within our Galaxy. Among the identified extragalactic sources, the large majority (14) is made up of type 1 AGNs (i.e. with broad emission lines); of these, 6 lie at redshift larger than 0.5 and one (IGR J12319-0749) has z = 3.12, which makes it the second farthest object detected in the INTEGRAL surveys up to now. The remaining AGNs are of type 2 (that is, with narrow emission lines only), and one of the two cases is confirmed as a pair of interacting Seyfert 2 galaxies. The Galactic objects are identified as two cataclysmic variables, one high-mass X-ray binary, one symbiotic binary and two chromospherically active stars, possibly of RS CVn type. The main physical parameters of these hard X-ray sources were also determined using the multiwavelength information available in the literature. We thus still find that AGNs are the most abundant population among hard X-ray objects identified through optical spectroscopy. Moreover, we note that the higher sensitivity of the more recent INTEGRAL surveys is now enabling the detection of high-redshift AGNs, thus allowing the exploration of the most distant hard X-ray emitting sources and possibly of the most extreme blazars. Based on observations collected at the following observatories: Cerro Tololo Interamerican Observatory (Chile); Observatorio del Roque de los Muchachos of the Instituto de Astrofísica de Canarias (Canary Islands, Spain); Astronomical Observatory of Bologna in Loiano (Italy); Astronomical Observatory of Asiago (Italy); Observatorio Astronómico Nacional (San Pedro Mártir, Mexico); Anglo-Australian Observatory (Siding Spring, Australia).

Obesity does not affect survival outcomes in extremity soft tissue sarcoma.

PubMed

Alamanda, Vignesh K; Moore, David C; Song, Yanna; Schwartz, Herbert S; Holt, Ginger E

2014-09-01

Obesity is a growing epidemic and has been associated with an increased frequency of complications after various surgical procedures. Studies also have shown adipose tissue to promote a microenvironment favorable for tumor growth. Additionally, the relationship between obesity and prognosis of soft tissue sarcomas has yet to be evaluated. We sought to assess if (1) obesity affects survival outcomes (local recurrence, distant metastasis, and death attributable to disease) in patients with extremity soft tissue sarcomas; and (2) whether obesity affected wound healing and other surgical complications after treatment. A BMI of 30 kg/m(2) or greater was used to define obesity. Querying our prospective database between 2001 and 2008, we identified 397 patients for the study; 154 were obese and 243 were not obese. Mean followup was 4.5 years (SD, 3.1 years) in the obese group and 3.9 years (SD, 3.2 years) in the nonobese group; the group with a BMI of 30 kg/m(2) or greater had a higher proportion of patients with followups of at least 2 years compared with the group with a BMI less than 30 kg/m(2) (76% versus 62%). Outcomes, including local recurrence, distant metastasis, and overall survival, were analyzed after patients were stratified by BMI. Multivariable survival models were used to identify independent predictors of survival outcomes. Wilcoxon rank sum test was used to compare continuous variables. Based on the accrual interval of 8 years, the additional followup of 5 years after data collection, and the median survival time for the patients with a BMI less than 30 kg/m(2) of 3 years, we were able to detect true median survival times in the patients with a BMI of 30 kg/m(2) of 2.2 years or less with 80% power and type I error rate of 0.05. Patients who were obese had similar survival outcomes and wound complication rates when compared with their nonobese counterparts. Patients who were obese were more likely to have lower-grade tumors (31% versus 20%; p = 0.021) and additional comorbidities including diabetes mellitus (26% versus 7%; p < 0.001), hypertension (63% versus 38%; p < 0.001), and smoking (49% versus 37%; p = 0.027). Regression analysis confirmed that even after accounting for certain tumor characteristics and comorbidities, obesity did not serve as an independent risk factor in affecting survival outcomes. Although the prevalence of obesity continues to increase and lead to many negative health consequences, it does not appear to adversely affect survival, local recurrence, or wound complication rates for patients with extremity soft tissue sarcomas. Level III, therapeutic study. See the Instructions for Authors for a complete description of levels of evidence.

Complexity and spectral analysis of the heart rate variability dynamics for distant prediction of paroxysmal atrial fibrillation with artificial intelligence methods.

PubMed

Chesnokov, Yuriy V

2008-06-01

Paroxysmal atrial fibrillation (PAF) is a serious arrhythmia associated with morbidity and mortality. We explore the possibility of distant prediction of PAF by analyzing changes in heart rate variability (HRV) dynamics of non-PAF rhythms immediately before PAF event. We use that model for distant prognosis of PAF onset with artificial intelligence methods. We analyzed 30-min non-PAF HRV records from 51 subjects immediately before PAF onset and at least 45min distant from any PAF event. We used spectral and complexity analysis with sample (SmEn) and approximate (ApEn) entropies and their multiscale versions on extracted HRV data. We used that features to train the artificial neural networks (ANNs) and support vector machine (SVM) classifiers to differentiate the subjects. The trained classifiers were further tested for distant PAF event prognosis on 16 subjects from independent database on non-PAF rhythm lasting from 60 to 320 min before PAF onset classifying the 30-min segments as distant or leading to PAF. We found statistically significant increase in 30-min non-PAF HRV recordings from 51 subjects in the VLF, LF, HF bands and total power (p<0.0001) before PAF event compared to PAF distant ones. The SmEn and ApEn analysis provided significant decrease in complexity (p<0.0001 and p<0.001) before PAF onset. For training ANN and SVM classifiers the data from 51 subjects were randomly split to training, validation and testing. ANN provided better results in terms of sensitivity (Se), specificity (Sp) and positive predictivity (Pp) compared to SVM which became biased towards positive case. The validation results of the ANN classifier we achieved: Se 76%, Sp 93%, Pp 94%. Testing ANN and SVM classifiers on 16 subjects with non-PAF HRV data preceding PAF events we obtained distant prediction of PAF onset with SVM classifier in 10 subjects (58+/-18 min in advance). ANN classifier provided distant prediction of PAF event in 13 subjects (62+/-21 min in advance). From the results of distant PAF prediction we conclude that ANN and SVM classifiers learned the changes in the HRV dynamics immediately before PAF event and successfully identified them during distant PAF prognosis on independent database. This confirms the reported in the literature results that corresponding changes in the HRV data occur about 60 min before PAF onset and proves the possibility of distant PAF prediction with ANN and SVM methods.

Quantitative assessment based on kinematic measures of functional impairments during upper extremity movements: A review.

PubMed

de los Reyes-Guzmán, Ana; Dimbwadyo-Terrer, Iris; Trincado-Alonso, Fernando; Monasterio-Huelin, Félix; Torricelli, Diego; Gil-Agudo, Angel

2014-08-01

Quantitative measures of human movement quality are important for discriminating healthy and pathological conditions and for expressing the outcomes and clinically important changes in subjects' functional state. However the most frequently used instruments for the upper extremity functional assessment are clinical scales, that previously have been standardized and validated, but have a high subjective component depending on the observer who scores the test. But they are not enough to assess motor strategies used during movements, and their use in combination with other more objective measures is necessary. The objective of the present review is to provide an overview on objective metrics found in literature with the aim of quantifying the upper extremity performance during functional tasks, regardless of the equipment or system used for registering kinematic data. A search in Medline, Google Scholar and IEEE Xplore databases was performed following a combination of a series of keywords. The full scientific papers that fulfilled the inclusion criteria were included in the review. A set of kinematic metrics was found in literature in relation to joint displacements, analysis of hand trajectories and velocity profiles. These metrics were classified into different categories according to the movement characteristic that was being measured. These kinematic metrics provide the starting point for a proposed objective metrics for the functional assessment of the upper extremity in people with movement disorders as a consequence of neurological injuries. Potential areas of future and further research are presented in the Discussion section. Copyright © 2014 Elsevier Ltd. All rights reserved.

HST image of Gravitational Lens G2237 + 305 or 'Einstein Cross'

NASA Technical Reports Server (NTRS)

1990-01-01

European Space Agency (ESA) Faint Object Camera (FOC) science image was taken from the Hubble Space Telescope (HST) of Gravitational Lens G2237 + 305 or 'Einstein Cross'. The gravitational lens G2237 + 305 or 'Einstein Cross' shows four images of a very distant quasar which has been multiple-imaged by a relatively nearby galaxy acting as a gravitational lens. The angular separation between the upper and lower images is 1.6 arc seconds. Photo was released from Goddard Space Flight Center (GSFC) 09-12-90.

A Quantitative Spectroscopic Comparison of Distant and Nearby Type Ia Supernovae: Tests for Homogeneity and Implications for Cosmology

DTIC Science & Technology

2006-11-14

Spectroscopic Data- Observations Longslit spectra of SNLS SN candidates were taken at the Gemini telescopes with the Gemini Multi-Object Spectrograph [ GMOS ...typical i’ magnitudes ranged from 21.8 to 24.5), and required exposure times of 1 to 2 hours over two to four exposures. The GMOS R400 grating (400 lines...extra 360 seconds. The extra overhead time is often minimised by choosing a small nod distance, or by employing the Electronic N&S mode. The GMOS

Visual control of navigation in insects and its relevance for robotics.

PubMed

Srinivasan, Mandyam V

2011-08-01

Flying insects display remarkable agility, despite their diminutive eyes and brains. This review describes our growing understanding of how these creatures use visual information to stabilize flight, avoid collisions with objects, regulate flight speed, detect and intercept other flying insects such as mates or prey, navigate to a distant food source, and orchestrate flawless landings. It also outlines the ways in which these insights are now being used to develop novel, biologically inspired strategies for the guidance of autonomous, airborne vehicles. Copyright © 2011 Elsevier Ltd. All rights reserved.

A Chandra Snapshot Survey of Extremely Red Quasars from SDSS BOSS and WISE

NASA Astrophysics Data System (ADS)

Garmire, Gordon

2017-09-01

We propose Chandra snapshot observations of a sample of 15 extremely red and highly luminous quasars at z > 2. These Type 1 objects have recently been discovered via the SDSS BOSS and WISE surveys, and they are among the most-luminous quasars in the Universe. They appear to be part of the missing evolutionary link as merger-induced starburst galaxies transform into typical ultraviolet luminous quasars. Our aim is to efficiently gather X-ray information about a sufficiently large sample of these objects that general conclusions about their basic X-ray properties, especially obscuration level and luminosity, can be drawn reliably. The results will also allow effective targeting of promising objects in longer X-ray spectroscopic observations.

Radiation therapy for Bowen's disease of the skin

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lukas VanderSpek, Lauren A.; Pond, Gregory R.; Wells, Woodrow

2005-10-01

Purpose: To assess the clinical outcome in the radiation therapy (RT) of squamous carcinoma in situ of the skin (Bowen's disease). We focused on the local control rate and the toxicity according to the biologically effective dose (BED). Methods and Materials: A retrospective review was performed on 44 patients with Bowen's disease treated at Princess Margaret Hospital from April 1985 to November 2000. RT was the primary treatment for 32 patients, whereas 12 received RT for residual disease after local ablative therapy. Lesions were located as follows: scalp, 9 patients (20%); face, 12 (27%); trunk, 6 (14%), extremity, 12 (27%),more » perianal, 3 (7%), and penis, 2 (5%). Orthovoltage X-rays were used in the majority (39 of 44, 89%). There was no standard fractionation regimen: some physicians prescribed high doses, as for invasive skin cancer, whereas others prescribed lower doses because of the noninvasive nature of the disease, a sensitive anatomic location (e.g., extremity), or large treatment area. Because of the variations in fractionation regimens, BED was used as a common metric for biologic effect in the comparison of different regimens and analyzed for correlation with recurrence and toxicity. Local control was defined as the lack of persistent or recurrent disease at the treated site for the follow-up period. Grade 4 toxicity was defined as necrosis (cartilage/bone damage) and/or ulceration for a duration of >3 months. Results: The mean patient age was 67.7 years, and the male/female ratio was 29:15. The median pretreatment lesion size was 2.65 cm{sup 2} (range, 0.07-34.56 cm{sup 2}). Complete remission was achieved in 42 patients, with follow-up unavailable for the remaining 2 patients. Subsequently, 3 patients experienced recurrences at 0.2, 1.1, and 1-1.5 years after complete remission. One recurrence was Bowen's disease (local); the others were squamous cell carcinoma (one local, one marginal). Four patients experienced a new squamous lesion at a distant cutaneous site. As of last follow-up, 32 patients (73%) were known to be alive. Median follow-up was 2.6 years (range, 0-11.8 years). All but 3 patients were disease-free at last follow-up, 1 of whom died with distant, but not local disease. The 5-year overall survival rate was 68%. Biologically effective dose was not associated with recurrence. The crude local control rate was 93%. There was a trend toward higher radiation doses for smaller pretreatment tumor and field sizes. The BED did not correlate with Grade 4 toxicity; however, the three cases of Grade 4 toxicity occurred in patients treated with hypofractionated regimens (dose per fraction >4 Gy) for extremity lesions. Conclusions: Radiation therapy is an effective treatment option for Bowen's disease of the skin. Local recurrences seem to be equally low in patients treated with high- and low-dose regimens. Avoiding hypofractionated regimens (dose per fraction >4 Gy) in extremity locations might reduce the risk of Grade 4 toxicity.« less

Metronidazole as a protector of cells from electromagnetic radiation of extremely high frequencies

NASA Astrophysics Data System (ADS)

Kuznetsov, Pavel E.; Malinina, Ulia A.; Popyhova, Era B.; Rogacheva, Svetlana M.; Somov, Alexander U.

2006-08-01

It is well known that weak electromagnetic fields of extremely high frequencies cause significant modification of the functional status of biological objects of different levels of organization. The aim of the work was to study the combinatory effect of metronidazole - the drug form of 1-(2'hydroxiethil)-2-methil-5-nitroimidazole - and electromagnetic radiation of extremely high frequencies (52...75 GHz) on the hemolytic stability of erythrocytes and hemotaxis activity of Infusoria Paramecium caudatum.

A Cause and A Solution for the Underprediction of Extreme Wave Events in the Northeast Pacific

NASA Astrophysics Data System (ADS)

Ellenson, A. N.; Ozkan-Haller, H. T.; Thomson, J.; Brown, A. C.; Haller, M. C.

2016-12-01

Along the coastlines of Washington and Oregon, at least one 10 m wave height event occurs every year, and the strongest storms produce wave heights of 14-15 m. Extremely high wave heights can cause severe damage to coastal infrastructure and pose hazards to stakeholders along the coast. A system which can accurately predict such sea states is important for quantifying risk and aiding in preparation for extreme wave events. This study explores how to optimize forecast model performance for extreme wave events by utilizing different physics packages or wind input in four model configurations. The different wind input products consist of a reanalyzed Global Forecasting System (GFS) wind input and a Climate Forecast System Reanalysis (CFSR) from the National Center of Environmental Prediction (NCEP). The physics packages are the Tolman-Chalikov (1996) ST2 physics package and the Ardhuin et al (2009) ST4 physics package associated with version 4.18 of WaveWatch III. A hindcast was previously performed to assess the wave character along the Pacific Northwest Coastline for wave energy applications. Inspection of hindcast model results showed that the operational model, which consisted of ST2 physics and GFS wind, underpredicted events where wave height exceeded six meters.The under-prediction is most severe for cases with the combined conditions of a distant cyclone and a strong coastal jet. Three such cases were re-analyzed with the four model configurations. Model output is compared with observations at NDBC buoy 46050, offshore of Newport, OR. The model configuration consisting of ST4 physics package and CFSR wind input performs best as compared with the original model, reducing significant wave height underprediction from 1.25 m to approximately 0.67 m and mean wave direction error from 30 degrees to 17 degrees for wave heights greater than 6 m. Spectral analysis shows that the ST4-CFSR model configuration best resolves southerly wave energy, and all model configurations tend to overestimate northerly wave energy. This directional distinction is important when attempting to identify which atmospheric feature has induced the extreme wave energy.

Anatomic Tumor Location Influences the Success of Contemporary Limb-Sparing Surgery and Radiation Among Adults With Soft Tissue Sarcomas of the Extremities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Korah, Mariam P., E-mail: mariam.philip@gmail.com; Deyrup, Andrea T.; Monson, David K.

2012-02-01

Purpose: To examine the influence of anatomic location in the upper extremity (UE) vs. lower extremity (LE) on the presentation and outcomes of adult soft tissue sarcomas (STS). Methods and Materials: From 2001 to 2008, 118 patients underwent limb-sparing surgery (LSS) and external beam radiotherapy (RT) with curative intent for nonrecurrent extremity STS. RT was delivered preoperatively in 96 and postoperatively in 22 patients. Lesions arose in the UE in 28 and in the LE in 90 patients. Patients with UE lesions had smaller tumors (4.5 vs. 9.0 cm, p < 0.01), were more likely to undergo a prior excisionmore » (43 vs. 22%, p = 0.03), to have close or positive margins after resection (71 vs. 49%, p = 0.04), and to undergo postoperative RT (32 vs. 14%, p = 0.04). Results: Five-year actuarial local recurrence-free and distant metastasis-free survival rates for the entire group were 85 and 74%, with no difference observed between the UE and LE cohorts. Five-year actuarial probability of wound reoperation rates were 4 vs. 29% (p < 0.01) in the UE and LE respectively. Thigh lesions accounted for 84% of the required wound reoperations. The distribution of tumors within the anterior, medial, and posterior thigh compartments was 51%, 26%, and 23%. Subset analysis by compartment showed no difference in the probability of wound reoperation between the anterior and medial/posterior compartments (29 vs. 30%, p = 0.68). Neurolysis was performed during resection in (15%, 5%, and 67%, p < 0.01) of tumors in the anterior, medial, and posterior compartments. Conclusions: Tumors in the UE and LE differ significantly with respect to size and management details. The anatomy of the UE poses technical impediments to an R0 resection. Thigh tumors are associated with higher wound reoperation rates. Tumor resection in the posterior thigh compartment is more likely to result in nerve injury. A better understanding of the inherent differences between tumors in various extremity sites will assist in individualizing treatment.« less

New Target for an Old Method: Hubble Measures Globular Cluster Parallax

NASA Astrophysics Data System (ADS)

Hensley, Kerry

2018-05-01

Measuring precise distances to faraway objects has long been a challenge in astrophysics. Now, one of the earliest techniques used to measure the distance to astrophysical objects has been applied to a metal-poor globular cluster for the first time.A Classic TechniqueAn artists impression of the European Space Agencys Gaia spacecraft. Gaia is on track to map the positions and motions of a billion stars. [ESA]Distances to nearby stars are often measured using the parallax technique tracing the tiny apparent motion of a target star against the background of more distant stars as Earth orbits the Sun. This technique has come a long way since it was first used in the 1800s to measure the distance to stars a few tens of light-years away; with the advent of space observatories like Hipparcos and Gaia, parallax can now be used to map the positions of stars out to thousands of light-years.Precise distance measurements arent only important for setting the scale of the universe, however; they can also help us better understand stellar evolution over the course of cosmic history. Stellar evolution models are often anchored to a reference star cluster, the properties of which must be known precisely. These precise properties can be readily determined for young, nearby open clusters using parallax measurements. But stellar evolution models that anchor on themore-distant, ancient, metal-poor globular clusters have been hampered by theless-precise indirect methods used tomeasure distance to these faraway clusters until now.Top: An image of NGC 6397 overlaid with the area scanned by Hubble (dashed green) and the footprint of the camera (solid green). The blue ellipse represents the parallax motion of a star in the cluster, exaggerated by a factor of ten thousand. Bottom: An example scan from this field. [Adapted from Brown et al. 2018]New Measurement to an Old ClusterThomas Brown (Space Telescope Science Institute) and collaborators used the Hubble Space Telescope todetermine the distance to NGC 6397, one of the nearest metal-poor globular clusters and anchor for one stellar population model. Brown and coauthors used a technique called spatial scanning to greatly broaden the reach of the parallax method.Spatial scanning was initially developed as a way to increase the signal-to-noise of exoplanet transit observations, but it has also greatly improved the prospects of astrometry precisely determining the separations between astronomical objects. In spatial scanning, the telescope moves while the exposure is being taken, spreading the light out across many pixels.Unprecedented PrecisionThis technique allowed the authors to achieve a precision of 20100microarcseconds. From the observed parallax angle of just 0.418 milliarcseconds (for reference, the moons angular size is about 5 million times larger on the sky!), Brown and collaborators refined the distance to NGC 6397 to 7,795 light-years, with a measurement error of only a few percent.Using spatial scanning, Hubble can make parallax measurements of nearby globular clusters, while Gaia has the potential to reach even farther. Looking ahead, the measurement made by Brown and collaborators can be combined with the recently released Gaia data to trim the uncertainty down to just 1%. This highlights the power of space telescopes to make extremely precise measurements of astoundingly large distances informing our models and helping us measure the universe.CitationThomas Brown et al 2018ApJL856 L6. doi:10.3847/2041-8213/aab55a

Extreme Ultraviolet Explorer. Long look at the next window

NASA Technical Reports Server (NTRS)

Maran, Stephen P.

1991-01-01

The Extreme Ultraviolet Explorer (EUVE) will map the entire sky to determine the existence, direction, brightness, and temperature of thousands of objects that are sources of so-called extreme ultraviolet (EUV) radiation. The EUV spectral region is located between the x-ray and ultraviolet regions of the electromagnetic spectrum. From the sky survey by EUVE, astronomers will determine the nature of sources of EUV light in our galaxy, and infer the distribution of interstellar gas for hundreds of light years around the solar system. It is from this gas and the accompanying dust in space that new stars and solar systems are born and to which evolving and dying stars return much of their material in an endless cosmic cycle of birth, death, and rebirth. Besides surveying the sky, astronomers will make detailed studies of selected objects with EUVE to determine their physical properties and chemical compositions. Also, they will learn about the conditions that prevail and the processes at work in stars, planets, and other sources of EUV radiation, maybe even quasars. The EUVE mission and instruments are described. The objects that EUVE will likely find are described.

Distant and Distributed Learners Are Two Sides of the Same Coin.

ERIC Educational Resources Information Center

Barron, Brette Barclay

2002-01-01

An academic librarian at the University of South Carolina, faced with providing online resources for distant and distributed learners, examines whether there is any difference between distant and distributed learners. Illustrates changes brought on by implementation of information technologies. Discusses seeking a new definition, meeting…

Photo-acoustic and video-acoustic methods for sensing distant sound sources

NASA Astrophysics Data System (ADS)

Slater, Dan; Kozacik, Stephen; Kelmelis, Eric

2017-05-01

Long range telescopic video imagery of distant terrestrial scenes, aircraft, rockets and other aerospace vehicles can be a powerful observational tool. But what about the associated acoustic activity? A new technology, Remote Acoustic Sensing (RAS), may provide a method to remotely listen to the acoustic activity near these distant objects. Local acoustic activity sometimes weakly modulates the ambient illumination in a way that can be remotely sensed. RAS is a new type of microphone that separates an acoustic transducer into two spatially separated components: 1) a naturally formed in situ acousto-optic modulator (AOM) located within the distant scene and 2) a remote sensing readout device that recovers the distant audio. These two elements are passively coupled over long distances at the speed of light by naturally occurring ambient light energy or other electromagnetic fields. Stereophonic, multichannel and acoustic beam forming are all possible using RAS techniques and when combined with high-definition video imagery it can help to provide a more cinema like immersive viewing experience. A practical implementation of a remote acousto-optic readout device can be a challenging engineering problem. The acoustic influence on the optical signal is generally weak and often with a strong bias term. The optical signal is further degraded by atmospheric seeing turbulence. In this paper, we consider two fundamentally different optical readout approaches: 1) a low pixel count photodiode based RAS photoreceiver and 2) audio extraction directly from a video stream. Most of our RAS experiments to date have used the first method for reasons of performance and simplicity. But there are potential advantages to extracting audio directly from a video stream. These advantages include the straight forward ability to work with multiple AOMs (useful for acoustic beam forming), simpler optical configurations, and a potential ability to use certain preexisting video recordings. However, doing so requires overcoming significant limitations typically including much lower sample rates, reduced sensitivity and dynamic range, more expensive video hardware, and the need for sophisticated video processing. The ATCOM real time image processing software environment provides many of the needed capabilities for researching video-acoustic signal extraction. ATCOM currently is a powerful tool for the visual enhancement of atmospheric turbulence distorted telescopic views. In order to explore the potential of acoustic signal recovery from video imagery we modified ATCOM to extract audio waveforms from the same telescopic video sources. In this paper, we demonstrate and compare both readout techniques for several aerospace test scenarios to better show where each has advantages.

The space telescope scientific instruments

NASA Technical Reports Server (NTRS)

Leckrone, D. S.

1980-01-01

The paper describes the space telescope with a 2.4 m aperture to be launched at 500 km altitude in late 1983. Four axial-bay and one radial-bay scientific instrument, a wide-field and planetary camera, a faint-object camera, a faint-object spectrograph, and a high-speed photometer are to be installed to conduct the initial observations. The axial instruments are constrained to envelopes with dimensions 0.9 x 0.9 x 2.2 m and their masses cannot exceed 317 kg. The observatory will also be equipped with fine-guidance sensors and a microprocessor. The design concepts of the instruments are outlined and some of the astronomical capabilities including studies of distant and local galaxies, physical properties of quasars, interrelations between quasars and active galactic nuclei are mentioned.

Quasars.

PubMed

Smith, H J

1966-11-01

A short historical outline of the discovery and a description of observed properties of quasars introduces questions as to their nature. Some of the principal arguments concerning their reality, distance, intrinsic properties and age lead to the conclusion that, while there is room for other points of view; a strong case can be made for the interpretation, on which quasars are the most distant observable objects in the known universe. To produce such luminosities over times of thousands to millions of years requires the presence of millions of solar masses. For each quasar this enormous mass may be concentrated into a single object, in which case novel physics comes into play. Whatever the final interpretation, quasars seem certain to illuminate such questions as the origin and evolution of galaxies, perhaps also the structure and origin of the universe.

Generalized extreme gust wind speeds distributions

USGS Publications Warehouse

Cheng, E.; Yeung, C.

2002-01-01

Since summer 1996, the US wind engineers are using the extreme gust (or 3-s gust) as the basic wind speed to quantify the destruction of extreme winds. In order to better understand these destructive wind forces, it is important to know the appropriate representations of these extreme gust wind speeds. Therefore, the purpose of this study is to determine the most suitable extreme value distributions for the annual extreme gust wind speeds recorded in large selected areas. To achieve this objective, we are using the generalized Pareto distribution as the diagnostic tool for determining the types of extreme gust wind speed distributions. The three-parameter generalized extreme value distribution function is, thus, reduced to either Type I Gumbel, Type II Frechet or Type III reverse Weibull distribution function for the annual extreme gust wind speeds recorded at a specific site.With the considerations of the quality and homogeneity of gust wind data collected at more than 750 weather stations throughout the United States, annual extreme gust wind speeds at selected 143 stations in the contiguous United States were used in the study. ?? 2002 Elsevier Science Ltd. All rights reserved.

The genomes of four tapeworm species reveal adaptations to parasitism.

PubMed

Tsai, Isheng J; Zarowiecki, Magdalena; Holroyd, Nancy; Garciarrubio, Alejandro; Sánchez-Flores, Alejandro; Brooks, Karen L; Tracey, Alan; Bobes, Raúl J; Fragoso, Gladis; Sciutto, Edda; Aslett, Martin; Beasley, Helen; Bennett, Hayley M; Cai, Xuepeng; Camicia, Federico; Clark, Richard; Cucher, Marcela; De Silva, Nishadi; Day, Tim A; Deplazes, Peter; Estrada, Karel; Fernández, Cecilia; Holland, Peter W H; Hou, Junling; Hu, Songnian; Huckvale, Thomas; Hung, Stacy S; Kamenetzky, Laura; Keane, Jacqueline A; Kiss, Ferenc; Koziol, Uriel; Lambert, Olivia; Liu, Kan; Luo, Xuenong; Luo, Yingfeng; Macchiaroli, Natalia; Nichol, Sarah; Paps, Jordi; Parkinson, John; Pouchkina-Stantcheva, Natasha; Riddiford, Nick; Rosenzvit, Mara; Salinas, Gustavo; Wasmuth, James D; Zamanian, Mostafa; Zheng, Yadong; Cai, Jianping; Soberón, Xavier; Olson, Peter D; Laclette, Juan P; Brehm, Klaus; Berriman, Matthew

2013-04-04

Tapeworms (Cestoda) cause neglected diseases that can be fatal and are difficult to treat, owing to inefficient drugs. Here we present an analysis of tapeworm genome sequences using the human-infective species Echinococcus multilocularis, E. granulosus, Taenia solium and the laboratory model Hymenolepis microstoma as examples. The 115- to 141-megabase genomes offer insights into the evolution of parasitism. Synteny is maintained with distantly related blood flukes but we find extreme losses of genes and pathways that are ubiquitous in other animals, including 34 homeobox families and several determinants of stem cell fate. Tapeworms have specialized detoxification pathways, metabolism that is finely tuned to rely on nutrients scavenged from their hosts, and species-specific expansions of non-canonical heat shock proteins and families of known antigens. We identify new potential drug targets, including some on which existing pharmaceuticals may act. The genomes provide a rich resource to underpin the development of urgently needed treatments and control.

Enrichment and single-cell analysis of circulating tumor cells

PubMed Central

Song, Yanling; Tian, Tian; Shi, Yuanzhi; Liu, Wenli; Zou, Yuan; Khajvand, Tahereh; Wang, Sili; Zhu, Zhi

2017-01-01

Up to 90% of cancer-related deaths are caused by metastatic cancer. Circulating tumor cells (CTCs), a type of cancer cell that spreads through the blood after detaching from a solid tumor, are essential for the establishment of distant metastasis for a given cancer. As a new type of liquid biopsy, analysis of CTCs offers the possibility to avoid invasive tissue biopsy procedures with practical implications for diagnostics. The fundamental challenges of analyzing and profiling CTCs are the extremely low abundances of CTCs in the blood and the intrinsic heterogeneity of CTCs. Various technologies have been proposed for the enrichment and single-cell analysis of CTCs. This review aims to provide in-depth insights into CTC analysis, including various techniques for isolation of CTCs with capture methods based on physical and biochemical principles, and single-cell analysis of CTCs at the genomic, proteomic and phenotypic level, as well as current developmental trends and promising research directions. PMID:28451298

The fossil record of evolution: Data on diversification and extinction

NASA Technical Reports Server (NTRS)

Sepkoski, J. J., Jr.

1986-01-01

Synoptic studies of the fossil record of complex life on Earth indicate increasingly that extinction, and especially mass extinction, were extremely important driving forces in the history of life. Analysis of a new compilation of geologic ranges for 25,000 genera of marine animals suggests that extinction events were much more frequent in occurrence and variable in magnitude than previously suspected. At least 30 well documented and potential mass extinctions were identified in the dataset. The most recent event, distributed over 260 to 0 ma. exhibit a stationary periodicity of 26.1 + or - 1 ma, implicating a cosmological forcing mechanism. Earlier events, especially in the 575 to 450 ma interval, are more frequent, possibly indicating either a breakdown of periodicity in the more distant past; and as yet undemonstrated diminution of the period length; or frequent aperiodic terrestrial perturbations of a less stable biota superimposed upon the cosmological periodicity.

A telescopic jib for continuous adjustment

NASA Technical Reports Server (NTRS)

Etzler, C. C.

1979-01-01

For special space applications, e.g. for experiments distant from any orbital platforms or manipulators a new kind of jibs with extreme extension capacity has to be designed. Considering the requirements, the telescopic principle is found to be the most promising. For the choice of the stiff structure, design criteria are evaluated. Special effort deals with the drive system. An electromechanical system can satisfy the requirements. First results of the development of such a drive are presented. The most significant features are: A telescopic assembly of tubes which can be mutually moved by a short spindle in the center of the package. An elastically suspended screw is located at the bottom of each tube. For the jib extension, these screws will be linked with the spindle. The control of their sequence and the adjustment of tubes in mutual end positions are performed by latches. A functional model proved the basic idea.