Sample records for facilitate long-distance interactions

  1. A Distance Education Classroom Designed to Facilitate Synchronous Learner and Instructor Interactions

    ERIC Educational Resources Information Center

    Bernstein, Stuart P.

    2013-01-01

    The purpose of this study was to determine whether a live, synchronous distance delivery technology would facilitate interaction, immediacy, and presence between an instructor and his contiguous and remote classrooms, and whether it would facilitate interaction between the two groups of students. This study researched the opinions of students on…

  2. Membrane nanotubes facilitate long-distance interactions between natural killer cells and target cells

    PubMed Central

    Chauveau, Anne; Aucher, Anne; Eissmann, Philipp; Vivier, Eric; Davis, Daniel M.

    2010-01-01

    Membrane nanotubes are membranous tethers that physically link cell bodies over long distances. Here, we present evidence that nanotubes allow human natural killer (NK) cells to interact functionally with target cells over long distances. Nanotubes were formed when NK cells contacted target cells and moved apart. The frequency of nanotube formation was dependent on the number of receptor/ligand interactions and increased on NK cell activation. Most importantly, NK cell nanotubes contained a submicron scale junction where proteins accumulated, including DAP10, the signaling adaptor that associates with the activating receptor NKG2D, and MHC class I chain-related protein A (MICA), a cognate ligand for NKG2D, as occurs at close intercellular synapses between NK cells and target cells. Quantitative live-cell fluorescence imaging suggested that MICA accumulated at small nanotube synapses in sufficient numbers to trigger cell activation. In addition, tyrosine-phosphorylated proteins and Vav-1 accumulated at such junctions. Functionally, nanotubes could aid the lysis of distant target cells either directly or by moving target cells along the nanotube path into close contact for lysis via a conventional immune synapse. Target cells moving along the nanotube path were commonly polarized such that their uropods faced the direction of movement. This is the opposite polarization than for normal cell migration, implying that nanotubes can specifically drive target cell movement. Finally, target cells that remained connected to an NK cell by a nanotube were frequently lysed, whereas removing the nanotube using a micromanipulator reduced lysis of these target cells. PMID:20212116

  3. Function of YY1 in Long-Distance DNA Interactions

    PubMed Central

    Atchison, Michael L.

    2014-01-01

    During B cell development, long-distance DNA interactions are needed for V(D)J somatic rearrangement of the immunoglobulin (Ig) loci to produce functional Ig genes, and for class switch recombination (CSR) needed for antibody maturation. The tissue-specificity and developmental timing of these mechanisms is a subject of active investigation. A small number of factors are implicated in controlling Ig locus long-distance interactions including Pax5, Yin Yang 1 (YY1), EZH2, IKAROS, CTCF, cohesin, and condensin proteins. Here we will focus on the role of YY1 in controlling these mechanisms. YY1 is a multifunctional transcription factor involved in transcriptional activation and repression, X chromosome inactivation, Polycomb Group (PcG) protein DNA recruitment, and recruitment of proteins required for epigenetic modifications (acetylation, deacetylation, methylation, ubiquitination, sumoylation, etc.). YY1 conditional knock-out indicated that YY1 is required for B cell development, at least in part, by controlling long-distance DNA interactions at the immunoglobulin heavy chain and Igκ loci. Our recent data show that YY1 is also required for CSR. The mechanisms implicated in YY1 control of long-distance DNA interactions include controlling non-coding antisense RNA transcripts, recruitment of PcG proteins to DNA, and interaction with complexes involved in long-distance DNA interactions including the cohesin and condensin complexes. Though common rearrangement mechanisms operate at all Ig loci, their distinct temporal activation along with the ubiquitous nature of YY1 poses challenges for determining the specific mechanisms of YY1 function in these processes, and their regulation at the tissue-specific and B cell stage-specific level. The large numbers of post-translational modifications that control YY1 functions are possible candidates for regulation. PMID:24575094

  4. Long-Distance Interactions Regulate the Structure and Resilience of Coastal Ecosystems

    NASA Astrophysics Data System (ADS)

    van de Koppel, Johan; van der Heide, Tjisse; Altieri, Andrew H.; Eriksson, Britas Klemens; Bouma, Tjeerd J.; Olff, Han; Silliman, Brian R.

    2015-01-01

    Mounting evidence indicates that spatial interactions are important in structuring coastal ecosystems. Until recently, however, most of this work has been focused on seemingly exceptional systems that are characterized by regular, self-organized patterns. In this review, we document that interactions that operate at long distances, beyond the direct neighborhood of individual organisms, are more common and have much more far-reaching implications for coastal ecosystems than was previously realized. We review studies from a variety of ecosystem types—including cobble beaches, mussel beds, coral reefs, seagrass meadows, and mangrove forests—that reveal a startling interplay of positive and negative interactions between habitats across distances of up to a kilometer. In addition to classical feeding relations, alterations of physical conditions constitute an important part of these long-distance interactions. This entanglement of habitats has crucial implications for how humans manage coastal ecosystems, and evaluations of anthropogenic impact should explicitly address long-distance and system-wide effects before we deem these human activities to be causing little harm.

  5. Facilitating Distance Education.

    ERIC Educational Resources Information Center

    Rossman, Mark H., Ed.; Rossman, Maxine E., Ed.

    1995-01-01

    This collection of articles on distance learning reflects the perspectives and concerns of the learner and the facilitator of learning in distance education setting. Eight chapters are included: (1) "The Evolution and Advantages of Distance Education" (John E. Cantelon) traces the history of distance education and demonstrates how it transcends…

  6. Does polyploidy facilitate long-distance dispersal?

    PubMed Central

    Linder, H. Peter; Barker, Nigel P.

    2014-01-01

    Background and Aims The ability of plant lineages to reach all continents contributes substantially to their evolutionary success. This is exemplified by the Poaceae, one of the most successful angiosperm families, in which most higher taxa (tribes, subfamilies) have global distributions. Due to the old age of the ocean basins relative to the major angiosperm radiations, this is only possible by means of long-distance dispersal (LDD), yet the attributes of lineages with successful LDD remain obscure. Polyploid species are over-represented in invasive floras and in the previously glaciated Arctic regions, and often have wider ecological tolerances than diploids; thus polyploidy is a candidate attribute of successful LDD. Methods The link between polyploidy and LDD was explored in the globally distributed grass subfamily Danthonioideae. An almost completely sampled and well-resolved species-level phylogeny of the danthonioids was used, and the available cytological information was assembled. The cytological evolution in the clade was inferred using maximum likelihood (ML) as implemented in ChromEvol. The biogeographical evolution in the clade was reconstructed using ML and Bayesian approaches. Key Results Numerous increases in ploidy level are demonstrated. A Late Miocene–Pliocene cycle of polyploidy is associated with LDD, and in two cases (the Australian Rytidosperma and the American Danthonia) led to secondary polyploidy. While it is demonstrated that successful LDD is more likely in polyploid than in diploid lineages, a link between polyploidization events and LDD is not demonstrated. Conclusions The results suggest that polyploids are more successful at LDD than diploids, and that the frequent polyploidy in the grasses might have facilitated the extensive dispersal among continents in the family, thus contributing to their evolutionary success. PMID:24694830

  7. Virtual interactive presence for real-time, long-distance surgical collaboration during complex microsurgical procedures.

    PubMed

    Shenai, Mahesh B; Tubbs, R Shane; Guthrie, Barton L; Cohen-Gadol, Aaron A

    2014-08-01

    The shortage of surgeons compels the development of novel technologies that geographically extend the capabilities of individual surgeons and enhance surgical skills. The authors have developed "Virtual Interactive Presence" (VIP), a platform that allows remote participants to simultaneously view each other's visual field, creating a shared field of view for real-time surgical telecollaboration. The authors demonstrate the capability of VIP to facilitate long-distance telecollaboration during cadaveric dissection. Virtual Interactive Presence consists of local and remote workstations with integrated video capture devices and video displays. Each workstation mutually connects via commercial teleconferencing devices, allowing worldwide point-to-point communication. Software composites the local and remote video feeds, displaying a hybrid perspective to each participant. For demonstration, local and remote VIP stations were situated in Indianapolis, Indiana, and Birmingham, Alabama, respectively. A suboccipital craniotomy and microsurgical dissection of the pineal region was performed in a cadaveric specimen using VIP. Task and system performance were subjectively evaluated, while additional video analysis was used for objective assessment of delay and resolution. Participants at both stations were able to visually and verbally interact while identifying anatomical structures, guiding surgical maneuvers, and discussing overall surgical strategy. Video analysis of 3 separate video clips yielded a mean compositing delay of 760 ± 606 msec (when compared with the audio signal). Image resolution was adequate to visualize complex intracranial anatomy and provide interactive guidance. Virtual Interactive Presence is a feasible paradigm for real-time, long-distance surgical telecollaboration. Delay, resolution, scaling, and registration are parameters that require further optimization, but are within the realm of current technology. The paradigm potentially enables remotely

  8. Long-distance communication facilitates cooperation among wild spotted hyaenas, Crocuta crocuta

    PubMed Central

    Gersick, Andrew S.; Cheney, Dorothy L.; Schneider, Jennifer M.; Seyfarth, Robert M.; Holekamp, Kay E.

    2015-01-01

    Calls that catalyse group defence, as in the mobbing of predators, appear to facilitate cooperation by recruiting receivers to act collectively. However, even when such signals reliably precede cooperative behaviour, the extent to which the calls function as recruitment signals is unclear. Calls might simply arouse listeners’ attention, setting off a cascade of independent responses to the threat. By contrast, they might convey information, for example, about signaller identity and the nature of a threat that affects receivers’ decisions to participate. We explored this distinction by investigating a possible long-distance recruitment call used by spotted hyaenas. These social carnivores live in fission–fusion clans and individuals disperse widely within their territories. Putative recruitment calls must therefore attract receivers that are distant from the inciting threat and free to opt out of risky collective aggression. Hyaenas compete with lions over food, and neighbouring clans sometimes engage in violent border clashes. These high-stakes contests are decided based on numerical asymmetries, so hyaenas can only protect critical resources if the dispersed clan can converge quickly at conflict sites. We recorded and analysed whoop bouts produced in multiple contexts and found that bouts produced in response to signs of lion–hyaena conflict had shorter inter-whoop intervals than spontaneous ‘display’ bouts. In subsequent field playback experiments, resting hyaenas were significantly more likely to move in response to ‘recruitment’ bouts with shortened intervals than to otherwise identical ‘display’ bouts. Whereas only stimulus type predicted movement, lower-ranked subjects responded most quickly, perhaps because their feeding opportunities depend on arriving early at any kill site. Results demonstrate that hyaenas possess a signal that can reliably recruit allies across long distances, despite moderating effects of individual circumstances on

  9. Long-distance communication and signal amplification in systemic acquired resistance

    PubMed Central

    Shah, Jyoti; Zeier, Jürgen

    2013-01-01

    Systemic acquired resistance (SAR) is an inducible defense mechanism in plants that confers enhanced resistance against a variety of pathogens. SAR is activated in the uninfected systemic (distal) organs in response to a prior (primary) infection elsewhere in the plant. SAR is associated with the activation of salicylic acid (SA) signaling and the priming of defense responses for robust activation in response to subsequent infections. The activation of SAR requires communication by the primary infected tissues with the distal organs. The vasculature functions as a conduit for the translocation of factors that facilitate long-distance intra-plant communication. In recent years, several metabolites putatively involved in long-distance signaling have been identified. These include the methyl ester of SA (MeSA), the abietane diterpenoid dehydroabietinal (DA), the dicarboxylic acid azelaic acid (AzA), and a glycerol-3-phosphate (G3P)-dependent factor. Long-distance signaling by some of these metabolites also requires the lipid-transfer protein DIR1 (DEFECTIVE IN INDUCED RESISTANCE 1). The relative contribution of these factors in long-distance signaling is likely influenced by environmental conditions, for example light. In the systemic leaves, the AGD2-LIKE DEFENSE RESPONSE PROTEIN1 (ALD1)-dependent production of the lysine catabolite pipecolic acid (Pip), FLAVIN-DEPENDENT MONOOXYGENASE1 (FMO1) signaling, as well as SA synthesis and downstream signaling are required for the activation of SAR. This review summarizes the involvement and interaction between long-distance SAR signals and details the recently discovered role of Pip in defense amplification and priming that allows plants to acquire immunity at the systemic level. Recent advances in SA signaling and perception are also highlighted. PMID:23440336

  10. Competition and facilitation in industrial barrens: variation in performance of mountain birch seedlings with distance from nurse plants.

    PubMed

    Eränen, Janne K; Kozlov, Mikhail V

    2007-04-01

    In stressful environments inter-plant facilitation is an important phenomenon co-occurring with competition. However, most experiments in natural ecosystems have only contrasted "sheltered" and "exposed" microsites, thus missing possible non-linearity of effects and not giving any information about the scale at which these interactions operate. In the current experiment we studied the net effect of nurse trees on mountain birch seedlings at various planting distances. Seedlings were planted in two highly stressful subarctic industrial barren sites around the nickel-copper smelter in Monchegorsk, NW Russia, at five distances (from 10 to 100 cm) from mature birch trees that were circa 100 cm in height. The survival and growth of seedlings were monitored for six years and the results were analyzed in respect to several environmental characteristics. Despite the fact that interaction strengths varied between years and between two study sites, both survival and growth of seedlings indicated optimum performance at middle distances and decreasing performance closer to and further from the nurse tree. We suggest that adverse effects on seedling performance at short distances are explained by competition and/or accumulation of pollutants under nurse plants, whereas at long distances these adverse effects appear due to lack of shelter, as shown by higher wind stress and lower soil water content.

  11. Facilitating interpersonal interaction and learning online: linking theory and practice.

    PubMed

    Sargeant, Joan; Curran, Vernon; Allen, Michael; Jarvis-Selinger, Sandra; Ho, Kendall

    2006-01-01

    An earlier study of physicians' perceptions of interactive online learning showed that these were shaped both by program design and quality and the quality and quantity of interpersonal interaction. We explore instructor roles in enhancing online learning through interpersonal interaction and the learning theories that inform these. This was a qualitative study using focus groups and interviews. Using purposive sampling, 50 physicians were recruited based on their experience with interactive online CME and face-to-face CME. Qualitative thematic and interpretive analysis was used. Two facilitation roles appeared key: creating a comfortable learning environment and enhancing the educational value of electronic discussions. Comfort developed gradually, and specific interventions like facilitating introductions and sharing experiences in a friendly, informative manner were helpful. As in facilitating effective small-group learning, instructors' thoughtful use of techniques that facilitated constructive interaction based on learner's needs and practice demands contributed to the educational value of interpersonal interactions. Facilitators require enhanced skills to engage learners in meaningful interaction and to overcome the transactional distance of online learning. The use of learning theories, including behavioral, cognitive, social, humanistic, and constructivist, can strengthen the educational design and facilitation of online programs. Preparation for online facilitation should include instruction in the roles and techniques required and the theories that inform them.

  12. Vacuolar sequestration capacity and long-distance metal transport in plants

    PubMed Central

    Peng, Jia-Shi; Gong, Ji-Ming

    2014-01-01

    The vacuole is a pivotal organelle functioning in storage of metabolites, mineral nutrients, and toxicants in higher plants. Accumulating evidence indicates that in addition to its storage role, the vacuole contributes essentially to long-distance transport of metals, through the modulation of Vacuolar sequestration capacity (VSC) which is shown to be primarily controlled by cytosolic metal chelators and tonoplast-localized transporters, or the interaction between them. Plants adapt to their environments by dynamic regulation of VSC for specific metals and hence targeting metals to specific tissues. Study of VSC provides not only a new angle to understand the long-distance root-to-shoot transport of minerals in plants, but also an efficient way to biofortify essential mineral nutrients or to phytoremediate non-essential metal pollution. The current review will focus on the most recent proceedings on the interaction mechanisms between VSC regulation and long-distance metal transport. PMID:24550927

  13. Vacuolar sequestration capacity and long-distance metal transport in plants.

    PubMed

    Peng, Jia-Shi; Gong, Ji-Ming

    2014-01-01

    The vacuole is a pivotal organelle functioning in storage of metabolites, mineral nutrients, and toxicants in higher plants. Accumulating evidence indicates that in addition to its storage role, the vacuole contributes essentially to long-distance transport of metals, through the modulation of Vacuolar sequestration capacity (VSC) which is shown to be primarily controlled by cytosolic metal chelators and tonoplast-localized transporters, or the interaction between them. Plants adapt to their environments by dynamic regulation of VSC for specific metals and hence targeting metals to specific tissues. Study of VSC provides not only a new angle to understand the long-distance root-to-shoot transport of minerals in plants, but also an efficient way to biofortify essential mineral nutrients or to phytoremediate non-essential metal pollution. The current review will focus on the most recent proceedings on the interaction mechanisms between VSC regulation and long-distance metal transport.

  14. Computer-facilitated assessment of disaster preparedness for remote hospitals in a long-distance, virtual tabletop drill model.

    PubMed

    Gillett, Brian; Silverberg, Mark; Roblin, Patricia; Adelaine, John; Valesky, Walter; Arquilla, Bonnie

    2011-06-01

    Emergency preparedness experts generally are based at academic or governmental institutions. A mechanism for experts to remotely facilitate a distant hospital's disaster readiness is lacking. The objective of this study was to develop and examine the feasibility of an Internet-based software tool to assess disaster preparedness for remote hospitals using a long-distance, virtual, tabletop drill. An Internet-based system that remotely acquires information and analyzes disaster preparedness for hospitals at a distance in a virtual, tabletop drill model was piloted. Nine hospitals in Cape Town, South Africa designated as receiving institutions for the 2010 FIFA World Cup Games and its organizers, utilized the system over a 10-week period. At one-week intervals, the system e-mailed each hospital's leadership a description of a stadium disaster and instructed them to login to the system and answer questions relating to their hospital's state of readiness. A total of 169 questions were posed relating to operational and surge capacities, communication, equipment, major incident planning, public relations, staff safety, hospital supplies, and security in each hospital. The system was used to analyze answers and generate a real-time grid that reflected readiness as a percent for each hospital in each of the above categories. It also created individualized recommendations of how to improve preparedness for each hospital. To assess feasibility of such a system, the end users' compliance and response times were examined. Overall, compliance was excellent with an aggregate response rate of 98%. The mean response interval, defined as the time elapsed between sending a stimuli and receiving a response, was eight days (95% CI = 8-9 days). A web-based data acquisition system using a virtual, tabletop drill to remotely facilitate assessment of disaster preparedness is efficient and feasible. Weekly reinforcement for disaster preparedness resulted in strong compliance.

  15. Interactivity in Distance Education: The National Open University of Nigeria (NOUN) Experience

    ERIC Educational Resources Information Center

    Ambe-Uva, Terhemba Nom

    2006-01-01

    The paper represents a study of students' experience of interactivity in distance education programmes at the National Open University of Nigeria (NOUN). Through surveys and focus groups with students, facilitators, and administrative support staff, we found out that interactivity is a key determinant of student success rate. Majority of the…

  16. Long-distance endosome trafficking drives fungal effector production during plant infection

    PubMed Central

    Bielska, Ewa; Higuchi, Yujiro; Schuster, Martin; Steinberg, Natascha; Kilaru, Sreedhar; Talbot, Nicholas J.; Steinberg, Gero

    2014-01-01

    To cause plant disease, pathogenic fungi can secrete effector proteins into plant cells to suppress plant immunity and facilitate fungal infection. Most fungal pathogens infect plants using very long strand-like cells, called hyphae, that secrete effectors from their tips into host tissue. How fungi undergo long-distance cell signalling to regulate effector production during infection is not known. Here we show that long-distance retrograde motility of early endosomes (EEs) is necessary to trigger transcription of effector-encoding genes during plant infection by the pathogenic fungus Ustilago maydis. We demonstrate that motor-dependent retrograde EE motility is necessary for regulation of effector production and secretion during host cell invasion. We further show that retrograde signalling involves the mitogen-activated kinase Crk1 that travels on EEs and participates in control of effector production. Fungal pathogens therefore undergo long-range signalling to orchestrate host invasion. PMID:25283249

  17. Long-distance endosome trafficking drives fungal effector production during plant infection.

    PubMed

    Bielska, Ewa; Higuchi, Yujiro; Schuster, Martin; Steinberg, Natascha; Kilaru, Sreedhar; Talbot, Nicholas J; Steinberg, Gero

    2014-10-06

    To cause plant disease, pathogenic fungi can secrete effector proteins into plant cells to suppress plant immunity and facilitate fungal infection. Most fungal pathogens infect plants using very long strand-like cells, called hyphae, that secrete effectors from their tips into host tissue. How fungi undergo long-distance cell signalling to regulate effector production during infection is not known. Here we show that long-distance retrograde motility of early endosomes (EEs) is necessary to trigger transcription of effector-encoding genes during plant infection by the pathogenic fungus Ustilago maydis. We demonstrate that motor-dependent retrograde EE motility is necessary for regulation of effector production and secretion during host cell invasion. We further show that retrograde signalling involves the mitogen-activated kinase Crk1 that travels on EEs and participates in control of effector production. Fungal pathogens therefore undergo long-range signalling to orchestrate host invasion.

  18. The Development of an Interaction Support System for International Distance Education

    ERIC Educational Resources Information Center

    Yueh, Hsiu-Ping; Lin, Weijane; Liu, Yi-Lin; Shoji, Tetsuo; Minoh, Michihiko

    2014-01-01

    This paper reports on the implementation of a learner identification system developed to facilitate real-time interaction in an international distance course. To increase the teacher immediacy and social presence, it proposes an integrative system for incorporating technology to improve the learning involvement, teaching effectiveness, and quality…

  19. Long distance quantum teleportation

    NASA Astrophysics Data System (ADS)

    Xia, Xiu-Xiu; Sun, Qi-Chao; Zhang, Qiang; Pan, Jian-Wei

    2018-01-01

    Quantum teleportation is a core protocol in quantum information science. Besides revealing the fascinating feature of quantum entanglement, quantum teleportation provides an ultimate way to distribute quantum state over extremely long distance, which is crucial for global quantum communication and future quantum networks. In this review, we focus on the long distance quantum teleportation experiments, especially those employing photonic qubits. From the viewpoint of real-world application, both the technical advantages and disadvantages of these experiments are discussed.

  20. Intramolecular Long-Distance Electron Transfer in Organic Molecules

    NASA Astrophysics Data System (ADS)

    Closs, Gerhard L.; Miller, John R.

    1988-04-01

    Intramolecular long-distance electron transfer (ET) has been actively studied in recent years in order to test existing theories in a quantitative way and to provide the necessary constants for predicting ET rates from simple structural parameters. Theoretical predictions of an ``inverted region,'' where increasing the driving force of the reaction will decrease its rate, have begun to be experimentally confirmed. A predicted nonlinear dependence of ET rates on the polarity of the solvent has also been confirmed. This work has implications for the design of efficient photochemical charge-separation devices. Other studies have been directed toward determining the distance dependence of ET reactions. Model studies on different series of compounds give similar distance dependences. When different stereochemical structures are compared, it becomes apparent that geometrical factors must be taken into account. Finally, the mechanism of coupling between donor and acceptor in weakly interacting systems has become of major importance. The theoretical and experimental evidence favors a model in which coupling is provided by the interaction with the orbitals of the intervening molecular fragments, although more experimental evidence is needed. Studies on intramolecular ET in organic model compounds have established that current theories give an adequate description of the process. The separation of electronic from nuclear coordinates is only a convenient approximation applied to many models, but in long-distance ET it works remarkably well. It is particularly gratifying to see Marcus' ideas finally confirmed after three decades of skepticism. By obtaining the numbers for quantitative correlations between rates and distances, these experiments have shown that saturated hydrocarbon fragments can ``conduct'' electrons over tens of angstroms. A dramatic demonstration of this fact has recently been obtained by tunneling electron microscopy on Langmuir-Blodgett films, showing in a

  1. Long Distance Caregiving

    MedlinePlus

    ... Navigation Bar Home Current Issue Past Issues Feature: Senior Living Long Distance Caregiving Past Issues / Summer 2009 ... when a crisis occurs. Get a directory of senior resources and services from the local library or ...

  2. Universality and tails of long-range interactions in one dimension

    NASA Astrophysics Data System (ADS)

    Valiente, Manuel; Öhberg, Patrik

    2017-07-01

    Long-range interactions and, in particular, two-body potentials with power-law long-distance tails are ubiquitous in nature. For two bosons or fermions in one spatial dimension, the latter case being formally equivalent to three-dimensional s -wave scattering, we show how generic asymptotic interaction tails can be accounted for in the long-distance limit of scattering wave functions. This is made possible by introducing a generalization of the collisional phase shifts to include space dependence. We show that this distance dependence is universal, in that it does not depend on short-distance details of the interaction. The energy dependence is also universal, and is fully determined by the asymptotic tails of the two-body potential. As an important application of our findings, we describe how to eliminate finite-size effects with long-range potentials in the calculation of scattering phase shifts from exact diagonalization. We show that even with moderately small system sizes it is possible to accurately extract phase shifts that would otherwise be plagued with finite-size errors. We also consider multichannel scattering, focusing on the estimation of open channel asymptotic interaction strengths via finite-size analysis.

  3. Long working distance optical coherence tomography for pediatric imaging (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Qian, Ruobing; Carrasco-Zevallos, Oscar; Vajzovic, Lejla; Gramatikov, Boris I.; Guyton, David L.; Toth, Cynthia A.; Izatt, Joseph A.

    2016-03-01

    Conventional optical coherence tomography (OCT) systems have working distances of about 25 mm, and require cooperative subjects to immobilize and fixate on a target. Handheld OCT probes have also been demonstrated for successful imaging of pre-term infants and neonates up to ~1 year old. However, no technology yet exists for OCT in young children due to their lack of attention and inherent fear of large objects close to their face. In this work, we demonstrate a prototype retinal swept-source OCT system with a long working distance (from the last optical element to the subject's eye) to facilitate pediatric imaging. To reduce the footprint and weight of the system compared to the conventional 4f scheme, a novel 2f scanning configuration was implemented to achieve a working distance of 348mm with a +/- 8° scanning angle prior to cornea. Employing two custom-designed lenses, the system design resolution was nearly diffraction limited throughout a -8D to +5D refractive corrections. A fixation target displayed on a LCD monitor and an iris camera were used to facilitate alignment and imaging. Our prototype was tested in consented adult subjects and has the potential to facilitate imaging of young children. With this apparatus, young children could potentially sit comfortably in caretaker's lap while viewing entertainment on the fixation screen designed to direct their gaze into the imaging apparatus.

  4. [Osteoarthritis from long-distance running?].

    PubMed

    Hohmann, E; Wörtler, K; Imhoff, A

    2005-06-01

    Long distance running has become a fashionable recreational activity. This study investigated the effects of external impact loading on bone and cartilage introduced by performing a marathon race. Seven beginners were compared to six experienced recreational long distance runners and two professional athletes. All participants underwent magnetic resonance imaging of the hip and knee before and after a marathon run. Coronal T1 weighted and STIR sequences were used. The pre MRI served as a baseline investigation and monitored the training effect. All athletes demonstrated normal findings in the pre run scan. All but one athlete in the beginner group demonstrated joint effusions after the race. The experienced and professional runners failed to demonstrate pathology in the post run scans. Recreational and professional long distance runners tolerate high impact forces well. Beginners demonstrate significant changes on the post run scans. Whether those findings are a result of inadequate training (miles and duration) warrant further studies. We conclude that adequate endurance training results in adaptation mechanisms that allow the athlete to compensate for the stresses introduced by long distance running and do not predispose to the onset of osteoarthritis. Significant malalignment of the lower extremity may cause increased focal loading of joint and cartilage.

  5. Spectral long-range interaction of temporal incoherent solitons.

    PubMed

    Xu, Gang; Garnier, Josselin; Picozzi, Antonio

    2014-02-01

    We study the interaction of temporal incoherent solitons sustained by a highly noninstantaneous (Raman-like) nonlinear response. The incoherent solitons exhibit a nonmutual interaction, which can be either attractive or repulsive depending on their relative initial distance. The analysis reveals that incoherent solitons exhibit a long-range interaction in frequency space, which is in contrast with the expected spectral short-range interaction described by the usual approach based on the Raman-like spectral gain curve. Both phenomena of anomalous interaction and spectral long-range behavior of incoherent solitons are described in detail by a long-range Vlasov equation.

  6. Testing the limits of long-distance learning: learning beyond a three-segment window.

    PubMed

    Finley, Sara

    2012-01-01

    Traditional flat-structured bigram and trigram models of phonotactics are useful because they capture a large number of facts about phonological processes. Additionally, these models predict that local interactions should be easier to learn than long-distance ones because long-distance dependencies are difficult to capture with these models. Long-distance phonotactic patterns have been observed by linguists in many languages, who have proposed different kinds of models, including feature-based bigram and trigram models, as well as precedence models. Contrary to flat-structured bigram and trigram models, these alternatives capture unbounded dependencies because at an abstract level of representation, the relevant elements are locally dependent, even if they are not adjacent at the observable level. Using an artificial grammar learning paradigm, we provide additional support for these alternative models of phonotactics. Participants in two experiments were exposed to a long-distance consonant-harmony pattern in which the first consonant of a five-syllable word was [s] or [∫] ("sh") and triggered a suffix that was either [-su] or [-∫u] depending on the sibilant quality of this first consonant. Participants learned this pattern, despite the large distance between the trigger and the target, suggesting that when participants learn long-distance phonological patterns, that pattern is learned without specific reference to distance. Copyright © 2012 Cognitive Science Society, Inc.

  7. Testing the limits of long-distance learning: Learning beyond a three-segment window

    PubMed Central

    Finley, Sara

    2012-01-01

    Traditional flat-structured bigram and trigram models of phonotactics are useful because they capture a large number of facts about phonological processes. Additionally, these models predict that local interactions should be easier to learn than long-distance ones since long-distance dependencies are difficult to capture with these models. Long-distance phonotactic patterns have been observed by linguists in many languages, who have proposed different kinds of models, including feature-based bigram and trigram models, as well as precedence models. Contrary to flat-structured bigram and trigram models, these alternatives capture unbounded dependencies because at an abstract level of representation, the relevant elements are locally dependent, even if they are not adjacent at the observable level. Using an artificial grammar learning paradigm, we provide additional support for these alternative models of phonotactics. Participants in two experiments were exposed to a long-distance consonant harmony pattern in which the first consonant of a five-syllable word was [s] or [∫] ('sh') and triggered a suffix that was either [−su] or [−∫u] depending on the sibilant quality of this first consonant. Participants learned this pattern, despite the large distance between the trigger and the target, suggesting that when participants learn long-distance phonological patterns, that pattern is learned without specific reference to distance. PMID:22303815

  8. Vegetation pattern formation in semiarid systems induced by long-range competition in the absence of facilitation mechanisms.

    NASA Astrophysics Data System (ADS)

    Martinez-Garcia, Ricardo; Calabrese, Justin M.; Hernandez-Garcia, Emilio; Lopez, Cristobal

    2014-05-01

    Regular patterns and spatial organization of vegetation have been observed in many arid and semiarid ecosystems worldwide, covering a diverse range of plant taxa and soil types. A key common ingredient in these systems is that plant growth is severely limited by water availability, and thus plants likely compete strongly for water. The study of such patterns is especially interesting because their features may reveal much about the underlying physical and biological processes that generated them in addition to giving information on the characteristics of the ecosystem. It is possible, for instance, to infer their resilience against anthropogenic disturbances or climatic changes that could cause abrupt shifts in the system and lead it to a desert state. Therefore much research has focused on identifying the underlying mechanisms that can produce spatial patterning in water-limited systems (Klausmeier, 1999). They are believed to arise from the interplay between long-range competition and facilitation processes acting at smaller distances (Borgogno et al., 2009). This combination of mechanisms is justified by arguing that water percolates more readily through the soil in vegetated areas (short range), and that plants compete for water resources over greater distances via long lateral roots (long range). However, recent studies have shown that even in the limit of local facilitation patterns may still appear (Martinez-Garcia et al., 2013). In this work (Martinez-Garcia et al., 2013b), we show that, under rather general conditions, long-range competition alone is the minimal ingredient to shape gapped and stripped vegetation patterns typical of models that also account for facilitation in addition to competition. To this end we propose a simple, general model for the dynamics of vegetation, which includes only long-range competition between plants. Competition is introduced through a nonlocal term, where the kernel function quantifies the intensity of the interaction

  9. Long working distance interference microscope

    DOEpatents

    Sinclair, Michael B.; DeBoer, Maarten P.; Smith, Norman F.

    2004-04-13

    Disclosed is a long working distance interference microscope suitable for three-dimensional imaging and metrology of MEMS devices and test structures on a standard microelectronics probe station. The long working distance of 10-30 mm allows standard probes or probe cards to be used. This enables nanometer-scale 3-D height profiles of MEMS test structures to be acquired across an entire wafer. A well-matched pair of reference/sample objectives is not required, significantly reducing the cost of this microscope, as compared to a Linnik microinterferometer.

  10. Interactive Distance Learning in Connecticut.

    ERIC Educational Resources Information Center

    Pietras, Jesse John; Murphy, Robert J.

    This paper provides an overview of distance learning activities in Connecticut and addresses the feasibility of such activities. Distance education programs have evolved from the one dimensional electronic mail systems to the use of sophisticated digital fiber networks. The Middlesex Distance Learning Consortium has developed a long-range plan to…

  11. Semantic Interference and Facilitation: Understanding the Integration of Spatial Distance and Conceptual Similarity During Sentence Reading.

    PubMed

    Guerra, Ernesto; Knoeferle, Pia

    2018-01-01

    Existing evidence has shown a processing advantage (or facilitation) when representations derived from a non-linguistic context (spatial proximity depicted by gambling cards moving together) match the semantic content of an ensuing sentence. A match, inspired by conceptual metaphors such as 'similarity is closeness' would, for instance, involve cards moving closer together and the sentence relates similarity between abstract concepts such as war and battle. However, other studies have reported a disadvantage (or interference) for congruence between the semantic content of a sentence and representations of spatial distance derived from this sort of non-linguistic context. In the present article, we investigate the cognitive mechanisms underlying the interaction between the representations of spatial distance and sentence processing. In two eye-tracking experiments, we tested the predictions of a mechanism that considers the competition, activation, and decay of visually and linguistically derived representations as key aspects in determining the qualitative pattern and time course of that interaction. Critical trials presented two playing cards, each showing a written abstract noun; the cards turned around, obscuring the nouns, and moved either farther apart or closer together. Participants then read a sentence expressing either semantic similarity or difference between these two nouns. When instructed to attend to the nouns on the cards (Experiment 1), participants' total reading times revealed interference between spatial distance (e.g., closeness) and semantic relations (similarity) as soon as the sentence explicitly conveyed similarity. But when instructed to attend to the cards (Experiment 2), cards approaching (vs. moving apart) elicited first interference (when similarity was implicit) and then facilitation (when similarity was made explicit) during sentence reading. We discuss these findings in the context of a competition mechanism of interference and

  12. Neuromuscular factors associated with decline in long-distance running performance in master athletes.

    PubMed

    Brisswalter, Jeanick; Nosaka, Kazunori

    2013-01-01

    This review focuses on neuromuscular factors that may affect endurance performance in master athletes. During the last decade, due to the rapid increase in the number of master or veteran participants in endurance sporting competitions, many studies attempted to identify metabolic factors associated with the decrease in endurance, especially long-distance running performance with ageing, focusing on decreases in maximal oxygen consumption. However, neuromuscular factors have been less studied despite the well-known phenomena of strength loss with ageing. For master athletes to perform better in long-distance running events, it is important to reduce muscle fatigue and/or muscle damage, to improve locomotion efficiency and to facilitate recovery. To date, no consensus exists that regular endurance training is beneficial for improving locomotion efficiency, reducing muscle fatigue and muscle damage, and enhancing recovery capacity in master athletes. Some recent studies seem to indicate that master athletes have similar muscle damage to young athletes, but they require a longer recovery time after a long-distance running event. Further analyses of these parameters in master athletes require more experimental and practical interest from researchers and coaches. In particular, more attention should be directed towards the capacity to maintain muscle function with training and the role of neuromuscular factors in long-distance performance decline with ageing using a more cellular and molecular approach.

  13. Tablet Technology to Facilitate Improved Interaction and Communication with Students Studying Mathematics at a Distance

    ERIC Educational Resources Information Center

    Galligan, Linda; Hobohm, Carola; Loch, Birgit

    2012-01-01

    Teaching and learning of mathematics is challenging when lecturer and students are separated geographically. While student engagement and interaction with the course, with other students and with the lecturer is vital to mathematics learning, it is difficult to facilitate this electronically, because of the nature of mathematics. With tablet…

  14. Evolution of local facilitation in arid ecosystems.

    PubMed

    Kéfi, Sonia; van Baalen, Minus; Rietkerk, Max; Loreau, Michel

    2008-07-01

    In harsh environments, sessile organisms can make their habitat more hospitable by buffering environmental stress or increasing resource availability. Although the ecological significance of such local facilitation is widely established, the evolutionary aspects have been seldom investigated. Yet addressing the evolutionary aspects of local facilitation is important because theoretical studies show that systems with such positive interactions can exhibit alternative stable states and that such systems may suddenly become extinct when they evolve (evolutionary suicide). Arid ecosystems currently experience strong changes in climate and human pressures, but little is known about the effects of these changes on the selective pressures exerted on the vegetation. Here, we focus on the evolution of local facilitation in arid ecosystems, using a lattice-structured model explicitly considering local interactions among plants. We found that the evolution of local facilitation depends on the seed dispersal strategy. In systems characterized by short-distance seed dispersal, adaptation to a more stressful environment leads to high local facilitation, allowing the population to escape extinction. In contrast, systems characterized by long-distance seed dispersal become extinct under increased stress even when allowed to adapt. In this case, adaptation in response to climate change and human pressures could give the final push to the desertification of arid ecosystems.

  15. Crocodylus acutus (American Crocodile). Long distance juvenile movement

    USGS Publications Warehouse

    Crespo, Rafael; Beauchamp, Jeffrey S.; Mazzotti, Frank; Cherkiss, Michael S.

    2015-01-01

    the distance traveled ranged from 0.3 km to 90.2 km. The data showed that the smaller alligators moved greater distance than larger ones (Lance et al. 2011. Southeast Nat. 10:389–398). An ongoing 30 year mark and recapture study for Crocodylus acutus in Florida allowed us to look at long distance movement (>30 km) of juveniles (30km). Initial and most recent captures as a juvenile were used to analyze distances moved (Fig. 1). These distances were measured linearly between capture locations. Maximum linear distances of 76.3 km and 69.6 km were recorded for animals 4838 and 6662. All crocodiles moved from nesting habitat through potentially optimal nursery habitat prior to reaching their recapture locations. These juvenile long distance movements could be due to larger crocodiles facilitating their dispersal from the nest location (Lance et al. 2011. op. cit.). These data (Table 1.) support that there is exchange of individuals among the nesting colonies and our ongoing efforts to monitor this threatened species allow us to make observations of how juvenile crocodiles are moving throughout the landscape in an ecosystem currently undergoing restoration.

  16. Long-distance Lienard-Wiechert potentials and qq-bar spin dependence

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Childers, R.W.

    1987-12-15

    The long-range spin dependence of the qq interaction is considered in a model in which the confining potential is required to be the static limit of retarded scalar and vector potentials analogous to the Lienard-Wiechert potentials of classical electrodynamics. A generalization of Darwin's method is used to obtain the corresponding Hamiltonian. The long-distance spin-dependent interaction is found to be determined completely by only two potentials: namely, the static scalar and vector potentials. This is to be compared with the four potentials required in Eichten and Feinberg's general formulation. Two different solutions are allowed by Gromes's theorem. In one, the scalarmore » potential can be linear; in the other, it must be logarithmic.« less

  17. Understanding Long-distance Traveler Behavior : Supporting a Long-distance Passenger Travel Demand Model

    DOT National Transportation Integrated Search

    2013-01-01

    Long-distance trips in the United States can take 2 days or 2 weeks and may involve cars, buses, planes, or all three. Whether for business, to see family, or visit a national park, such a variety of trip characteristics requires a detailed understan...

  18. Rapid, Long-Distance Dispersal by Pumice Rafting

    PubMed Central

    Bryan, Scott E.; Cook, Alex G.; Evans, Jason P.; Hebden, Kerry; Hurrey, Lucy; Colls, Peter; Jell, John S.; Weatherley, Dion; Firn, Jennifer

    2012-01-01

    Pumice is an extremely effective rafting agent that can dramatically increase the dispersal range of a variety of marine organisms and connect isolated shallow marine and coastal ecosystems. Here we report on a significant recent pumice rafting and long-distance dispersal event that occurred across the southwest Pacific following the 2006 explosive eruption of Home Reef Volcano in Tonga. We have constrained the trajectory, and rate, biomass and biodiversity of transfer, discovering more than 80 species and a substantial biomass underwent a >5000 km journey in 7–8 months. Differing microenvironmental conditions on the pumice, caused by relative stability of clasts at the sea surface, promoted diversity in biotic recruitment. Our findings emphasise pumice rafting as an important process facilitating the distribution of marine life, which have implications for colonisation processes and success, the management of sensitive marine environments, and invasive pest species. PMID:22815770

  19. Application of distance learning to interactive seminar instruction in orthodontic residency programs.

    PubMed

    Bednar, Eric D; Hannum, Wallace M; Firestone, Allen; Silveira, Anibal M; Cox, Thomas D; Proffit, William R

    2007-11-01

    A series of experiments involving 3 orthodontic departments has shown that distance learning can be acceptable to residents and effective in teaching concepts that are fundamental to orthodontic practice. Residents in each department participated in distance seminars, clinical conferences, and clinical seminars via high-speed Internet connections. The acceptability of this form of instruction was judged from evaluation forms completed by the residents. Its effectiveness was judged from pretests and posttests on the seminar topics. The improvement from pretest to posttest scores after observing a sequence of distance seminars was similar to that with direct instruction. Orthodontic residents rated the educational experiences positively. Live participation in seminars via video conferencing was preferred to live observation or later observation of a recording, but observation provided similar improvement in test scores. The acceptability of the distance seminars appeared to be influenced by the instructor's personality and teaching style in facilitating interaction, the seminar subject, the residents' comfort level in dealing with this technology, and the sequence for interaction vs observation. Further development of recorded seminars with live follow-up discussions has the potential to supplement instruction in graduate orthodontic programs and help with the impending shortage of experienced full-time orthodontic faculty.

  20. Measuring Long-Distance Romantic Relationships: A Validity Study

    ERIC Educational Resources Information Center

    Pistole, M. Carole; Roberts, Amber

    2011-01-01

    This study investigated aspects of construct validity for the scores of a new long-distance romantic relationship measure. A single-factor structure of the long-distance romantic relationship index emerged, with convergent and discriminant evidence of external validity, high internal consistency reliability, and applied utility of the scores.…

  1. Long-Distance Wh-Movement and Long-Distance Wh-Movement Avoidance in L2 English: Evidence from French and Bulgarian Speakers

    ERIC Educational Resources Information Center

    Slavkov, Nikolay

    2015-01-01

    This article investigates spoken productions of complex questions with long-distance wh-movement in the L2 English of speakers whose first language is (Canadian) French or Bulgarian. Long-distance wh-movement is of interest as it can be argued that it poses difficulty in acquisition due to its syntactic complexity and related high processing load.…

  2. HEARING IMPAIRMENT AND HYPERTENSION AMONG LONG DISTANCE BUS DRIVERS

    PubMed Central

    Abdelmoneim, Ismail

    2003-01-01

    Objectives: To investigate the prevalence of possible hearing impairment and hypertension in long distance bus drivers compared to the city bus drivers in Abha city. Methods: This was a cross-sectional study involving 62 long distance bus drivers and 46 city bus drivers from October 2001 to March 2002. A specially-designed questionnaire was administered to the drivers to explore some of their socioeconomic backgrounds. A pure tone air conduction audiometry and blood pressure measurements were performed. Results: Long distance bus drivers’ workload is significantly higher than that of city drivers (total weekly hours 64.0±14.3 compared to 46.7±5.5). Hearing impairment was significantly more among long distance drivers in the frequencies of 250, 500, 1000 and 2000 Hz especially in the left ear even after age corrections. The prevalence of mild hearing loss and hypertension were also higher among the long distance drivers (19.4% vs 4.5% and 38.7% vs 13% respectively). Conclusion and recommendations: This study showed more hearing affection and a higher prevalence of hypertension among long distance bus drivers than their counterparts operating in the city. Their hearing acuity should be tested before they start work and regularly afterwards. The stresses and strains of the job should be further studied and relieved; and regular health checks including blood pressure monitoring are to be instituted. PMID:23012034

  3. Providing Quality Laboratories to Long-Distance Educational Programs.

    ERIC Educational Resources Information Center

    Gammon, Tammy; Sutton, John

    2003-01-01

    North Carolina State University (UNC) has been on the forefront of long-distance education by offering a Bachelor of Science in Engineering with a Mechatronics Concentration at its remote campus located at UNC Asheville. The program demonstrates that long-distance laboratories are feasible and should not be a stumbling block to offering…

  4. Entanglement Generation and Area Law with Long-Range Interactions

    NASA Astrophysics Data System (ADS)

    Gorshkov, Alexey

    In short-range interacting systems, the speed at which entanglement can be established between two separated points is limited by a constant Lieb-Robinson velocity. This same limit also leads to the so-called area-law bound on entanglement in one-dimensional gapped short-range interacting systems. In this talk, we will show that long-range interactions that decay with distance as a power law allow for faster entanglement generation and state transfer. We will also present sufficient conditions for the area law in gapped systems to hold even in the presence of long-range interactions.

  5. Role of Clay Minerals in Long-Distance Transport of Landslides in Valles Marineris, Mars

    NASA Astrophysics Data System (ADS)

    Watkins, J.; Ehlmann, B. L.; Yin, A.

    2014-12-01

    Long-runout (> 50 km) subaerial landslides are rare on Earth, but are common features episodically shaping Mars' Valles Marineris (VM) trough system over the past 3.5 billion years. They display two end-member morphologies: a thick-skinned inner zone, characterized by fault-bounded, rotated blocks near their source region, and a thin-skinned, exceptionally long-runout outer zone, characterized by thin sheets spreading over 10s of km across the trough floor. Four decades of studies on the latter have resulted in two main competing hypotheses to explain their long-distance transport: (1) movement of landslides over layers of trapped air or soft materials containing ice or snow, enabling basal lubrication, and (2) fluidization of landslide materials with or without the presence of water and volatiles. To address this issue, we examine the mineralogic composition of landslides across VM using Compact Reconnaissance Imaging Spectrometer for Mars (CRISM) near-infrared spectral data analysis coupled with detailed geologic mapping and morphometric analysis of satellite images. Our survey reveals a general correlation between transport distance, significant lateral spreading, and the presence of hydrated silicates among VM landslides. Given that smectite clay absorbs water into its layered crystal structure and can reduce the friction coefficient by a factor of three v. that of dry rocks, these results suggest that hydrated silicates played a decisive role in facilitating long-runout landslide transport in VM. We propose that, concurrent with downslope failure and sliding of broken trough-wall rock, frontal landslide masses overrode and entrained hydrated-silicate-bearing trough-floor deposits, lubricating the basal sliding zones and permitting the landslide outer zones to spread laterally while moving forward over the low-friction surface. The key participation of hydrated silicates in episodic, sustained landslide activity throughout the canyon implies that clay minerals

  6. Effects of long distance translocation on corticosterone and testosterone levels in male rattlesnakes.

    PubMed

    Heiken, Kory H; Brusch, George A; Gartland, Sarah; Escallón, Camilo; Moore, Ignacio T; Taylor, Emily N

    2016-10-01

    Translocation is an increasingly common conservation tool used to augment declining populations or to remove nuisance animals from areas of human conflict. Studies show that venomous snakes translocated long distances may wander and experience increased mortality. However, potential sub-lethal physiological effects on translocated snakes remain unknown. We conducted an experimental study on free-ranging rattlesnakes to test the hypothesis that long distance translocation is stressful. The glucocorticoid response to translocation was variable among snakes. There was some evidence that translocation may be stressful, as baseline corticosterone levels in most snakes rose following translocation, whereas levels remained consistent in control snakes. Interestingly, testosterone levels rose dramatically following translocation, possibly reflecting effects of interaction with new environmental cues and/or resident snakes, or effects of navigation in a new environment. Corticosterone and testosterone were positively correlated. Our study shows that long distance translocation can affect steroid hormone concentrations in rattlesnakes, a result that should be taken into consideration when managing nuisance snakes or repatriating animals to the wild. Copyright © 2016 Elsevier Inc. All rights reserved.

  7. Metabolic profile of long-distance migratory flight and stopover in a shorebird.

    PubMed

    Landys, Meta M; Piersma, Theunis; Guglielmo, Christopher G; Jukema, Joop; Ramenofsky, Marilyn; Wingfield, John C

    2005-02-07

    Migrating birds often complete long non-stop flights during which body energy stores exclusively support energetic demands. The metabolic correlates of such long-distance travel in free-living migrants are as yet poorly studied. Bar-tailed godwits, Limosa lapponica taymyrensis, undertake a 4500 km flight to their single spring stopover site and thus provide an excellent model in which to determine the energy fuels associated with endurance travel. To this end, we evaluated plasma concentrations of six key metabolites in arriving godwits caught immediately upon landing near their stopover site. Initial metabolite levels were compared with levels after 5 h of inactive rest to determine how flight per se affects energy metabolism. Birds refuelling on the stopover site were also examined. Arriving godwits displayed elevated plasma free fatty acids, glycerol and butyrate, confirming the importance of lipid fuel in the support of extended migratory activity. Further-more, elevated plasma triglycerides in these birds suggest that fatty acid provisioning is facilitated through hepatic synthesis and release of neutral lipids, as previously hypothesized for small migrants with high mass-specific metabolic rates. Finally, elevations in plasma uric acid suggest that protein breakdown contributes to the support of long-distance movement, to possibly maintain citric acid cycle intermediates, gluconeogenesis and/or water balance.

  8. Metabolic profile of long-distance migratory flight and stopover in a shorebird

    PubMed Central

    Landys, Mėta M.; Piersma, Theunis; Guglielmo, Christopher G.; Jukema, Joop; Ramenofsky, Marilyn; Wingfield, John C.

    2005-01-01

    Migrating birds often complete long non-stop flights during which body energy stores exclusively support energetic demands. The metabolic correlates of such long-distance travel in free-living migrants are as yet poorly studied. Bar-tailed godwits, Limosa lapponica taymyrensis, undertake a 4500 km flight to their single spring stopover site and thus provide an excellent model in which to determine the energy fuels associated with endurance travel. To this end, we evaluated plasma concentrations of six key metabolites in arriving godwits caught immediately upon landing near their stopover site. Initial metabolite levels were compared with levels after 5 h of inactive rest to determine how flight per se affects energy metabolism. Birds refuelling on the stopover site were also examined. Arriving godwits displayed elevated plasma free fatty acids, glycerol and butyrate, confirming the importance of lipid fuel in the support of extended migratory activity. Furthermore, elevated plasma triglycerides in these birds suggest that fatty acid provisioning is facilitated through hepatic synthesis and release of neutral lipids, as previously hypothesized for small migrants with high mass-specific metabolic rates. Finally, elevations in plasma uric acid suggest that protein breakdown contributes to the support of long-distance movement, to possibly maintain citric acid cycle intermediates, gluconeogenesis and/or water balance. PMID:15705555

  9. Perturbation of nuclear architecture by long-distance chromosome interactions.

    PubMed

    Dernburg, A F; Broman, K W; Fung, J C; Marshall, W F; Philips, J; Agard, D A; Sedat, J W

    1996-05-31

    Position-effect variegation (PEV) describes the stochastic transcriptional silencing of a gene positioned adjacent to heterochromatin. Using FISH, we have tested whether variegated expression of the eye-color gene brown in Drosophila is influenced by its nuclear localization. In embryonic nuclei, a heterochromatic insertion at the brown locus is always spatially isolated from other heterochromatin. However, during larval development this insertion physically associates with other heterochromatic regions on the same chromosome in a stochastic manner. These observations indicate that the brown gene is silenced by specific contact with centromeric heterochromatin. Moreover, they provide direct evidence for long-range chromosome interactions and their impact on three-dimensional nuclear architecture, while providing a cohesive explanation for the phenomenon of PEV.

  10. Support Groups in Distance Education. Knowledge Series.

    ERIC Educational Resources Information Center

    Robertshaw, Michael

    For most distance education (DE) systems, distance, time, and/or opportunity isolate learners from their teacher and their fellow students. To facilitate interaction, most DE systems include different types of support groups. Modern technology allows groups to interact effectively even though individuals are far apart. Technology may appear to be…

  11. Long Distance Reactor Antineutrino Flux Monitoring

    NASA Astrophysics Data System (ADS)

    Dazeley, Steven; Bergevin, Marc; Bernstein, Adam

    2015-10-01

    The feasibility of antineutrino detection as an unambiguous and unshieldable way to detect the presence of distant nuclear reactors has been studied. While KamLAND provided a proof of concept for long distance antineutrino detection, the feasibility of detecting single reactors at distances greater than 100 km has not yet been established. Even larger detectors than KamLAND would be required for such a project. Considerations such as light attenuation, environmental impact and cost, which favor water as a detection medium, become more important as detectors get larger. We have studied both the sensitivity of water based detection media as a monitoring tool, and the scientific impact such detectors might provide. A next generation water based detector may be able to contribute to important questions in neutrino physics, such as supernova neutrinos, sterile neutrino oscillations, and non standard electroweak interactions (using a nearby compact accelerator source), while also providing a highly sensitive, and inherently unshieldable reactor monitoring tool to the non proliferation community. In this talk I will present the predicted performance of an experimental non proliferation and high-energy physics program. Lawrence Livermore National Laboratory is operated by Lawrence Livermore National Security, LLC, for the U.S. Department of Energy, National Nuclear Security Administration under Contract DE-AC52-07NA27344. Release number LLNL-ABS-674192.

  12. Long-distance transport of signals during symbiosis

    PubMed Central

    Xie, Zhi-Ping; Illana, Antonio

    2011-01-01

    Legumes enter nodule symbioses with nitrogen-fixing bacteria (rhizobia), whereas most flowering plants establish symbiotic associations with arbuscular mycorrhizal (AM) fungi. Once first steps of symbiosis are initiated, nodule formation and mycorrhization in legumes is negatively controlled by a shoot-derived inhibitor (SDI), a phenomenon termed autoregulation. According to current views, autoregulation of nodulation and mycorrhization in legumes is regulated in a similar way. CLE peptides induced in response to rhizobial nodulation signals (Nod factors) have been proposed to represent the ascending long-distance signals to the shoot. Although not proven yet, these CLE peptides are likely perceived by leucine-rich repeat (LRR) autoregulation receptor kinases in the shoot. Autoregulation of mycorrhization in non-legumes is reminiscent to the phenomenon of “systemic acquired resistance” in plant-pathogen interactions. PMID:21455020

  13. Long distance tracking of birds

    NASA Technical Reports Server (NTRS)

    Cochran, W. W.

    1972-01-01

    The application of radio telemetry techniques to the long distance tracking of birds is discussed. The types of equipment developed and methods for attachment to a bird are described. The operating range of the radio transmitter receiver system is examined, and methods for acquiring and analyzing the data are explained.

  14. Identification of host factors potentially involved in RTM-mediated resistance during potyvirus long distance movement.

    PubMed

    Sofer, Luc; Cabanillas, Daniel Garcia; Gayral, Mathieu; Téplier, Rachèle; Pouzoulet, Jérôme; Ducousso, Marie; Dufin, Laurène; Bréhélin, Claire; Ziegler-Graff, Véronique; Brault, Véronique; Revers, Frédéric

    2017-07-01

    The long distance movement of potyviruses is a poorly understood step of the viral cycle. Only factors inhibiting this process, referred to as "Restricted TEV Movement" (RTM), have been identified in Arabidopsis thaliana. On the virus side, the potyvirus coat protein (CP) displays determinants required for long-distance movement and for RTM-based resistance breaking. However, the potyvirus CP was previously shown not to interact with the RTM proteins. We undertook the identification of Arabidopsis factors which directly interact with either the RTM proteins or the CP of lettuce mosaic virus (LMV). An Arabidopsis cDNA library generated from companion cells was screened with LMV CP and RTM proteins using the yeast two-hybrid system. Fourteen interacting proteins were identified. Two of them were shown to interact with CP and the RTM proteins suggesting that a multiprotein complex could be formed between the RTM proteins and virions or viral ribonucleoprotein complexes. Co-localization experiments in Nicotiana benthamiana showed that most of the viral and cellular protein pairs co-localized at the periphery of chloroplasts which suggests a putative role for plastids in this process.

  15. Long working distance incoherent interference microscope

    DOEpatents

    Sinclair, Michael B [Albuquerque, NM; De Boer, Maarten P [Albuquerque, NM

    2006-04-25

    A full-field imaging, long working distance, incoherent interference microscope suitable for three-dimensional imaging and metrology of MEMS devices and test structures on a standard microelectronics probe station. A long working distance greater than 10 mm allows standard probes or probe cards to be used. This enables nanometer-scale 3-dimensional height profiles of MEMS test structures to be acquired across an entire wafer while being actively probed, and, optionally, through a transparent window. An optically identical pair of sample and reference arm objectives is not required, which reduces the overall system cost, and also the cost and time required to change sample magnifications. Using a LED source, high magnification (e.g., 50.times.) can be obtained having excellent image quality, straight fringes, and high fringe contrast.

  16. Improving access to services and interactions with clients in Guatemala: the value of distance learning.

    PubMed

    Brambila, Carlos; Lopez, Felipe; Garcia-Colindres, Julio; Donis, Marco Vinicio

    2005-04-01

    To develop and test a distance-learning programme to improve the quality and efficiency of family planning services in Guatemala. The setting was rural family planning services in Guatemala. The study design was quasi-experimental with one intervention and one control group and with pre- and post-intervention measures. Two staff members from each of 20 randomly selected health districts were trained as leaders of the training programme. In turn, the 40 trainers trained a total of 240 service providers, under the supervision of four health area facilitators. The results were compared with 20 randomly selected control health districts. The intervention was a distance-learning programme including 40 in-class hours followed by 120 inservice practice hours spread over a 4-month period. Distinctively, the programme used a cascade approach to training, intensive supervision, and close monitoring and evaluation. Patient flow analysis was used to determine number of contacts, waiting times, and the interaction time between service providers and clients. Consultation observations were used to assess the quality and completeness of reproductive health information and services received by clients. The intervention showed a positive impact on reducing the number of contacts before the consultation and client waiting times. More complete services and better quality services were provided at intervention clinics. Some, but not all, of the study objectives were attained. The long-term impact of the intervention is as yet unknown. Distance-learning programmes are an effective methodology for training health professionals in rural areas.

  17. Intrusion of granitic magma into the continental crust facilitated by magma pulsing and dike-diapir interactions: Numerical simulations

    NASA Astrophysics Data System (ADS)

    Cao, Wenrong; Kaus, Boris J. P.; Paterson, Scott

    2016-06-01

    We conducted a 2-D thermomechanical modeling study of intrusion of granitic magma into the continental crust to explore the roles of multiple pulsing and dike-diapir interactions in the presence of visco-elasto-plastic rheology. Multiple pulsing is simulated by replenishing source regions with new pulses of magma at a certain temporal frequency. Parameterized "pseudo-dike zones" above magma pulses are included. Simulation results show that both diking and pulsing are crucial factors facilitating the magma ascent and emplacement. Multiple pulses keep the magmatic system from freezing and facilitate the initiation of pseudo-dike zones, which in turn heat the host rock roof, lower its viscosity, and create pathways for later ascending pulses of magma. Without diking, magma cannot penetrate the highly viscous upper crust. Without multiple pulsing, a single magma body solidifies quickly and it cannot ascent over a long distance. Our results shed light on the incremental growth of magma chambers, recycling of continental crust, and evolution of a continental arc such as the Sierra Nevada arc in California.

  18. Neurotrophin Signaling via Long-Distance Axonal Transport

    NASA Astrophysics Data System (ADS)

    Chowdary, Praveen D.; Che, Dung L.; Cui, Bianxiao

    2012-05-01

    Neurotrophins are a family of target-derived growth factors that support survival, development, and maintenance of innervating neurons. Owing to the unique architecture of neurons, neurotrophins that act locally on the axonal terminals must convey their signals across the entire axon for subsequent regulation of gene transcription in the cell nucleus. This long-distance retrograde signaling, a motor-driven process that can take hours or days, has been a subject of intense interest. In the last decade, live-cell imaging with high sensitivity has significantly increased our capability to track the transport of neurotrophins, their receptors, and subsequent signals in real time. This review summarizes recent research progress in understanding neurotrophin-receptor interactions at the axonal terminal and their transport dynamics along the axon. We emphasize high-resolution studies at the single-molecule level and also discuss recent technical advances in the field.

  19. Robotic long-distance telementoring in neurosurgery.

    PubMed

    Mendez, Ivar; Hill, Ron; Clarke, David; Kolyvas, George; Walling, Simon

    2005-03-01

    To test the feasibility of long-distance telementoring in neurosurgery by providing subspecialized expertise in real time to another neurosurgeon performing a surgical procedure in a remote location. A robotic telecollaboration system (Socrates; Computer Motion, Inc., Santa Barbara, CA) capable of controlling the movements of a robotic arm, of handling two-way video, and of audio communication as well as transmission of neuronavigational data from the remote operating room was used for the telementoring procedures. Four integrated services digital network lines with a total speed of transmission of 512 kilobytes per second provided telecommunications between a large academic center (Halifax, Nova Scotia) and a community-based center (Saint John, New Brunswick) located 400 km away. Long-distance telementoring was used in three craniotomies for brain tumors, a craniotomy for an arteriovenous malformation, a carotid endarterectomy, and a lumbar laminectomy. There were no surgical complications during the procedures, and all patients had uneventful outcomes. The neurosurgeons in the remote location believed that the input from the mentors was useful in all of the cases and was crucial in the removal of a mesial temporal lobe glioma and resection of an occipital arteriovenous malformation. Our initial experience with long-distance robotic-assisted telementoring in six cases indicates that telementoring is feasible, reliable, and safe. Although still in its infancy, telementoring has the potential to improve surgical care, to enhance neurosurgical training, and to have a major impact on the delivery of neurosurgical services throughout the world.

  20. Ultra-Long-Distance Hybrid BOTDA/Ф-OTDR

    PubMed Central

    Fu, Yun; Zhu, Richeng; Xue, Naitian; Lu, Chongyu; Zhang, Bin; Yang, Le; Atubga, David; Rao, Yunjiang

    2018-01-01

    In the distributed optical fiber sensing (DOFS) domain, simultaneous measurement of vibration and temperature/strain based on Rayleigh scattering and Brillouin scattering in fiber could have wide applications. However, there are certain challenges for the case of ultra-long sensing range, including the interplay of different scattering mechanisms, the interaction of two types of sensing signals, and the competition of pump power. In this paper, a hybrid DOFS system, which can simultaneously measure temperature/strain and vibration over 150 km, is elaborately designed via integrating the Brillouin optical time-domain analyzer (BOTDA) and phase-sensitive optical time-domain reflectometry (Ф-OTDR). Distributed Raman and Brillouin amplifications, frequency division multiplexing (FDM), wavelength division multiplexing (WDM), and time division multiplexing (TDM) are delicately fused to accommodate ultra-long-distance BOTDA and Ф-OTDR. Consequently, the sensing range of the hybrid system is 150.62 km, and the spatial resolution of BOTDA and Ф-OTDR are 9 m and 30 m, respectively. The measurement uncertainty of the BOTDA is ± 0.82 MHz. To the best of our knowledge, this is the first time that such hybrid DOFS is realized with a hundred-kilometer length scale. PMID:29587407

  1. Impact of long-range interactions on the disordered vortex lattice

    NASA Astrophysics Data System (ADS)

    Koopmann, J. A.; Geshkenbein, V. B.; Blatter, G.

    2003-07-01

    The interaction between the vortex lines in a type-II superconductor is mediated by currents. In the absence of transverse screening this interaction is long ranged, stiffening up the vortex lattice as expressed by the dispersive elastic moduli. The effect of disorder is strongly reduced, resulting in a mean-squared displacement correlator ≡<[u(R,L)-u(0,0)]2> characterized by a mere logarithmic growth with distance. Finite screening cuts the interaction on the scale of the London penetration depth λ and limits the above behavior to distances R<λ. Using a functional renormalization-group approach, we derive the flow equation for the disorder correlation function and calculate the disorder-averaged mean-squared relative displacement ∝ ln2σ(R/a0). The logarithmic growth (2σ=1) in the perturbative regime at small distances [A. I. Larkin and Yu. N. Ovchinnikov, J. Low Temp. Phys. 34, 409 (1979)] crosses over to a sub-logarithmic growth with 2σ=0.348 at large distances.

  2. Contributions of long-distance dispersal to population growth in colonising Pinus ponderosa populations.

    PubMed

    Lesser, Mark R; Jackson, Stephen T

    2013-03-01

    Long-distance dispersal is an integral part of plant species migration and population development. We aged and genotyped 1125 individuals in four disjunct populations of Pinus ponderosa that were initially established by long-distance dispersal in the 16th and 17th centuries. Parentage analysis was used to determine if individuals were the product of local reproductive events (two parents present), long-distance pollen dispersal (one parent present) or long-distance seed dispersal (no parents present). All individuals established in the first century at each site were the result of long-distance dispersal. Individuals reproduced at younger ages with increasing age of the overall population. These results suggest Allee effects, where populations were initially unable to expand on their own, and were dependent on long-distance dispersal to overcome a minimum-size threshold. Our results demonstrate that long-distance dispersal was not only necessary for initial colonisation but also to sustain subsequent population growth during early phases of expansion. © 2012 Blackwell Publishing Ltd/CNRS.

  3. 1978 All Indian Long Distance Runner's Training Camp. General Assessment.

    ERIC Educational Resources Information Center

    Churchill, Ward

    The All-Indian Long Distance Runner's Training Camp, predicated upon the fact that the Native American community has produced an inordinate number of long distance runners due to historical/environmental/sociological factors, has as its operational philosophy that academic achievement is stressed as a correlate to athletic success; that…

  4. Skin surface hydration decreases rapidly during long distance flights.

    PubMed

    Guéhenneux, Sabine; Gardinier, Sophie; Morizot, Frederique; Le Fur, Isabelle; Tschachler, Erwin

    2012-05-01

    Dehydration of the stratum corneum leads to sensations and symptoms of 'dry skin' such as skin tightness and itchiness. As these complaints are frequently experienced by airline travellers, the aim of this study was to investigate the changes in skin surface hydration during long distance flights. The study was performed on four healthy Caucasian, and on four Japanese women aged 29-39 years, travelling on long distance flights. They had stopped using skin care products at least 12 h before, and did not apply them during the flights. The air temperature and relative humidity inside the cabin, as well as skin capacitance of the face and forearm of participants, were registered at several time points before and during the flights. Relative humidity of the aircraft cabin dropped to levels below 10% within 2 h after take-off and stayed at this value throughout the flight. Skin capacitance decreased rapidly on both the face and forearms with most pronounced changes on the cheeks where it decreased by up to 37%. Our results demonstrate that during long distance flights, the aircraft cabin environment leads to a rapid decrease in stratum corneum hydration, an alteration, which probably accounts for the discomfort experienced by long distance aircraft travellers. © 2011 John Wiley & Sons A/S.

  5. The Long-Distance Binding of "ZIJI."

    ERIC Educational Resources Information Center

    Liejiong, XU

    1993-01-01

    Addresses "ziji," notorious long-distance reflexive in Chinese, which can take antecedent infinitively far away. Argues that theories concerned with anaphoric properties should be formed and evaluated on basis of following observations: no barriers can block anaphoric relation; and subjects of any clauses containing reflexive are its…

  6. Long-Distance Rescue and Slow Extinction Dynamics Govern Multiscale Metapopulations.

    PubMed

    Huth, Géraldine; Haegeman, Bart; Pitard, Estelle; Munoz, François

    2015-10-01

    Rare long-distance dispersal is known to be critical for species dynamics, but how the interplay between short- and long-distance colonization influences regional persistence in a fragmented habitat remains poorly understood. We propose a metapopulation model that combines local colonization within habitat islands and long-distance colonization between islands. We study how regional occupancy dynamics are affected by the multiscale colonization process. We find that the island size distribution (ISD) is a key driver of the long-term occupancy dynamics. When the ISD is heterogeneous-that is, when the size of islands is variable-we show that extinction dynamics become very slow. We demonstrate that this behavior is unrelated to the well-known extinction debt near the critical extinction threshold. Hence, this finding questions the equivalence between extinction debt and critical transitions in the context of metapopulation collapse. Furthermore, we show that long-distance colonization can rescue small islands from extinction and sustain a steady regional occupancy. These results provide novel theoretical and practical insights into extinction dynamics and persistence in fragmented habitats and are thus relevant for the design of conservation strategies.

  7. Interactive Distance Education: Improvisation Helps Bridge the Gap.

    ERIC Educational Resources Information Center

    Yucha, Carolyn B.

    1996-01-01

    Describes distance learning through the use of interactive duplex video and audio. Improvisation techniques force active participation by students. Addresses faculty concerns about the interrelationships between instructor and students and among students in distance education environments. (MKR)

  8. Cultural interaction and biological distance in postclassic period Mexico.

    PubMed

    Ragsdale, Corey S; Edgar, Heather J H

    2015-05-01

    Economic, political, and cultural relationships connected virtually every population throughout Mexico during Postclassic period (AD 900-1520). Much of what is known about population interaction in prehistoric Mexico is based on archaeological or ethnohistoric data. What is unclear, especially for the Postclassic period, is how these data correlate with biological population structure. We address this by assessing biological (phenotypic) distances among 28 samples based upon a comparison of dental morphology trait frequencies, which serve as a proxy for genetic variation, from 810 individuals. These distances were compared with models representing geographic and cultural relationships among the same groups. Results of Mantel and partial Mantel matrix correlation tests show that shared migration and trade are correlated with biological distances, but geographic distance is not. Trade and political interaction are also correlated with biological distance when combined in a single matrix. These results indicate that trade and political relationships affected population structure among Postclassic Mexican populations. We suggest that trade likely played a major role in shaping patterns of interaction between populations. This study also shows that the biological distance data support the migration histories described in ethnohistoric sources. © 2015 Wiley Periodicals, Inc.

  9. Identifying impediments to long-distance mammal migrations.

    PubMed

    Seidler, Renee G; Long, Ryan A; Berger, Joel; Bergen, Scott; Beckmann, Jon P

    2015-02-01

    In much of the world, the persistence of long-distance migrations by mammals is threatened by development. Even where human population density is relatively low, there are roads, fencing, and energy development that present barriers to animal movement. If we are to conserve species that rely on long-distance migration, then it is critical that we identify existing migration impediments. To delineate stopover sites associated with anthropogenic development, we applied Brownian bridge movement models to high-frequency locations of pronghorn (Antilocapra americana) in the Greater Yellowstone Ecosystem. We then used resource utilization functions to assess the threats to long-distance migration of pronghorn that were due to fences and highways. Migrating pronghorn avoided dense developments of natural gas fields. Highways with relatively high volumes of traffic and woven-wire sheep fence acted as complete barriers. At crossings with known migration bottlenecks, use of high-quality forage and shrub habitat by pronghorn as they approached the highway was lower than expected based on availability of those resources. In contrast, pronghorn consistently utilized high-quality forage close to the highway at crossings with no known migration bottlenecks. Our findings demonstrate the importance of minimizing development in migration corridors in the future and of mitigating existing pressure on migratory animals by removing barriers, reducing the development footprint, or installing crossing structures. © 2014 Society for Conservation Biology.

  10. Use of recorded interactive seminars in orthodontic distance education.

    PubMed

    Miller, Kenneth T; Hannum, Wallace M; Morley, Tarrl; Proffit, William R

    2007-09-01

    Our objective was evaluate the effectiveness and acceptability of 3 methods of instructor interaction during distance learning with prerecorded seminars in orthodontic residencies and continuing education. After residents at 3 schools (Sydney, Australia; Winnipeg, Manitoba, Canada; and Manchester, United Kingdom) viewed a recorded interactive seminar, they discussed its content with the seminar leader at a distance via video conferencing, audio-only interaction by telephone, and Internet chat with Net Meeting software (Microsoft, Bellevue, Wash). The residents then completed evaluations containing both closed- and open-ended questions. In addition, attendees at the Iranian Orthodontic Congress also viewed a recorded seminar, had questions answered via an interpreter in a video conference, and completed summary evaluations. Video conferencing received the highest ratings and was never cited as the least favorite method of interaction. Telephone interaction was a close second in mean scores, and Internet chat was a distant third. All residents stated that they would like to be taught through distance education again. However, the Iranian orthodontists were less enthusiastic. Distance learning based on observation of recorded seminars and follow-up interaction is an acceptable method of instruction that can allow residents and practicing orthodontists access to various materials and experts, and perhaps help to ease the strains of current faculty shortages. More data are needed to determine whether video conferencing is worth the additional cost and complexity over audio-only interaction.

  11. Adding Interactivity to Web Based Distance Learning.

    ERIC Educational Resources Information Center

    Cafolla, Ralph; Knee, Richard

    Web Based Distance Learning (WBDL) is a form of distance learning based on providing instruction mainly on the World Wide Web. This paradigm has limitations, especially the lack of interactivity inherent in the Web. The purpose of this paper is to discuss some of the technologies the authors have used in their courses at Florida Atlantic…

  12. Relationship between radiation-induced aberrations in individual chromosomes and their DNA content: effects of interaction distance

    NASA Technical Reports Server (NTRS)

    Wu, H.; Durante, M.; Lucas, J. N.

    2001-01-01

    PURPOSE: To study the effect of the interaction distance on the frequency of inter- and intrachromosome exchanges in individual chromosomes with respect to their DNA content. Assumptions: Chromosome exchanges are formed by misrejoining of two DNA double-strand breaks (DSB) induced within an interaction distance, d. It is assumed that chromosomes in G(0)/G(1) phase of the cell cycle occupy a spherical domain in a cell nucleus, with no spatial overlap between individual chromosome domains. RESULTS: Formulae are derived for the probability of formation of inter-, as well as intra-, chromosome exchanges relating to the DNA content of the chromosome for a given interaction distance. For interaction distances <1 microm, the relative frequency of interchromosome exchanges predicted by the present model is similar to that by Cigarran et al. (1998) based on the assumption that the probability of interchromosome exchanges is proportional to the "surface area" of the chromosome territory. The "surface area" assumption is shown to be a limiting case of d-->0 in the present model. The present model also predicts that the probability of intrachromosome exchanges occurring in individual chromosomes is proportional to their DNA content with correction terms. CONCLUSION: When the interaction distance is small, the "surface area" distribution for chromosome participation in interchromosome exchanges has been expected. However, the present model shows that for the interaction distance as large as 1 microm, the predicted probability of interchromosome exchange formation is still close to the surface area distribution. Therefore, this distribution does not necessarily rule out the formation of complex chromosomal aberrations by long-range misrejoining of DSB.

  13. Levels of Interaction Provided by Online Distance Education Models

    ERIC Educational Resources Information Center

    Alhih, Mohammed; Ossiannilsson, Ebba; Berigel, Muhammet

    2017-01-01

    Interaction plays a significant role to foster usability and quality in online education. It is one of the quality standard to reveal the evidence of practice in online distance education models. This research study aims to evaluate levels of interaction in the practices of distance education centres. It is aimed to provide online distance…

  14. E-Readiness of Open and Distance Learning (ODL) Facilitators: Implications for Effective Mediation

    ERIC Educational Resources Information Center

    Nyoni, Jabulani

    2014-01-01

    This article is a narrative report of the findings from the analysis of multicultural facilitators' discourses on their e-readiness in the use of information and communication technologies (ICTs) affordances in open and distance learning (ODL) mediation experiences. First, the findings revealed by qualitative deconstructive discourse analysis…

  15. Interaction in Distance Nursing Education

    ERIC Educational Resources Information Center

    Boz Yuksekdag, Belgin

    2012-01-01

    The purpose of this study is to determine psychiatry nurses' attitudes toward the interactions in distance nursing education, and also scrunize their attitudes based on demographics and computer/Internet usage. The comparative relational scanning model is the method of this study. The research data were collected through "The Scale of Attitudes of…

  16. Learner-Content Interaction in Distance Education: The Weakest Link in Interaction Research

    ERIC Educational Resources Information Center

    Xiao, Junhong

    2017-01-01

    Interaction is a recurrent theme in the literature on distance education. Much of the research along these lines is dedicated to reciprocal interpersonal interaction, that is, learner-learner and learner-instructor interaction. But there is far less research interest in learner-content interaction despite its fundamental and critical role in…

  17. Mycorrhizal networks and distance from mature trees alter patterns of competition and facilitation in dry Douglas-fir forests.

    PubMed

    Teste, François P; Simard, Suzanne W

    2008-11-01

    The distribution of dry Douglas-fir forests in western North America is expected to shift northward with climate change and disappear from the grassland interface in the southern interior of British Columbia. This shift may be accentuated by clearcutting, a common harvesting practice that aims to reduce the competitive effects of residual mature trees on new regeneration, but in so doing, ignores their facilitative effects. In this study, we investigated the net effects of competition from and facilitation by mature trees retained on harvested sites on seedling establishment in the dry interface Douglas-fir forests. We demonstrate that access to a mycorrhizal network (MN) and proximity to trees have important influences on seedling performance. On six sites, we established trenched plots around 24 mature Pseudotsuga menziesii var. glauca (Douglas-fir) trees, then planted Douglas-fir seedlings into four mesh treatments that served to restrict MN access (i.e., planted into mesh bags with 0.5-, 35-, or 250-microm pores, or without mesh) or into impermeable bags (grown in isolation) at four distances (0.5, 1.0, 2.5, or 5.0 m). Seedling survival tended to be greater and water stress lower where seedlings had full access to the MN. Seedling height, shoot biomass, needle biomass, and nutrient uptake peaked at 2.5-5.0 m from mature trees. Seedlings 0.5 m from mature trees had lower CO2 assimilation rates and wood delta(13)C compared to seedlings 5.0 m away. Competition for soil resources was highest near mature trees but facilitation was relatively greater at further distances, resulting in a zone of net benefit for seedlings. These results show that intraspecific tree-seedling interactions are both competitive and facilitative in dry Douglas-fir forests, and that they are spatially dependent. After disturbance, maintaining residual mature trees may be important for their beneficial regeneration zones.

  18. Experimental detection of long-distance interactions between biomolecules through their diffusion behavior: numerical study.

    PubMed

    Nardecchia, Ilaria; Spinelli, Lionel; Preto, Jordane; Gori, Matteo; Floriani, Elena; Jaeger, Sebastien; Ferrier, Pierre; Pettini, Marco

    2014-08-01

    The dynamical properties and diffusive behavior of a collection of mutually interacting particles are numerically investigated for two types of long-range interparticle interactions: Coulomb-electrostatic and dipole-electrodynamic. It is shown that when the particles are uniformly distributed throughout the accessible space, the self-diffusion coefficient is always lowered by the considered interparticle interactions, irrespective of their attractive or repulsive character. This fact is also confirmed by a simple model to compute the correction to the Brownian diffusion coefficient due to the interactions among the particles. These interactions are also responsible for the onset of dynamical chaos and an associated chaotic diffusion which still follows an Einstein-Fick-like law for the mean-square displacement as a function of time. Transitional phenomena are observed for Coulomb-electrostatic (repulsive) and dipole-electrodynamic (attractive) interactions considered both separately and in competition. The outcomes reported in this paper clearly indicate a feasible experimental method to probe the activation of resonant electrodynamic interactions among biomolecules.

  19. Confession-building, long-distance networks, and the organization of Jesuit science.

    PubMed

    Harris, S J

    1996-01-01

    The ability of the Society of Jesus to engage in a broad and enduring tradition of scientific activity is here addressed in terms of its programmatic commitment to the consolidation and extension of the Catholic confession (i.e., to a multipronged program of confession-building) and its mastery of the administrative apparatus necessary to operate long-distance networks. The Society's early move into two major apostolates, one in education and the other in the overseas missions, brought Jesuits into regular contact with the educated elites of Europe and at the same time placed the society's missionaries in remote parts of the natural world. The modes of organization of travel and communication required by the Society's long-distance networks (i.e., the training and deployment of reliable agents willing to work under direction in remote locations and capable of providing trustworthy reports and observations to their superiors through regular exchange of correspondence) not only facilitated scientific communication and collaboration within the order, it also provided Jesuits with the resources they needed to engage successfully in 'ministries among the learned'. Evidence of a sustained attempt by Jesuit authors to assume the role of Kulturträger is found in the several genres of scientific publications that dominate the society's scientific corpus. Thus the society's early recognition of the "apostolic value" of scientific publications in recruiting friends and allies among Europe's intellectual elites, I argue, allowed a robust interest in natural knowledge to emerge as a legitimate part of the Jesuit vocation.

  20. Design of ocular for optical sight with long exit pupil distance

    NASA Astrophysics Data System (ADS)

    Zhu, Zhongyao; Li, Yuyao; Tian, Ailing

    2017-02-01

    In order to solve the injury of optical sight to shooters, which is produced by recoil for using artillery or firearms, and the usage problems of shooters' eye mask, headband and gas mask, the ocular with long exit pupil distance has been designed based on optical sighting system. The optical properties and aberration characteristics of ocular with long exit pupil distance has been analyzed, the structural style with positive-positive-negative three lens groups has been put forward. According to the aberration theory and the isoplanatic image formation principle, the focal power assignment expression has been deduced by adopting analytical method. By using of optical design software ZEMAX, the ocular with long exit pupil distance has been designed, the focal length of system is 20mm, the exit pupil diameter is 4mm, the field angle is 40°, the distance of exit pupil is 41mm, and the relative eye relief is greater than 2. The design results show if this method has been adopted, the transfer functions of each field are all greater than 0.15 when the ocular with long exit pupil distance locates on 45lp/mm, which can meet the use requirements of visual optical instruments.

  1. Distance learning through synchronous interactive television.

    PubMed

    Hall, Janis L

    2007-01-01

    The advent and popularity of asynchronous online learning has somewhat obscured a standby technology developed over the last two decades. Interactive videoconferencing, sometimes called "interactive television," though not as glamorous and popular a topic at distance-learning conferences, is still alive and well at many institutions. Three or four years ago, many of us were led to believe that interactive television would go the way of the dinosaurs-everything would soon be in an asynchronous format or on individual desktops. There would no longer be any need for elaborately designed classrooms, networks, and operations staff. To date, this prediction has not come true. In fact, synchronous interactive television has experienced significant growth as newer, easier, and cheaper technologies allow institutions to reach more students with less resource investment. Faculty and students, while appreciating the convenience of asynchronous delivery, still express a need for synchronous communication. This article explores the issues involved in synchronous distance education, the current technologies and proposed future developments, and best practices in terms of classroom design, faculty use, and operational issues. It is not a research article but an anecdotal case study based on Washington State University's experiences over the last 20 years in developing and adapting to new synchronous technologies and creating the support and technical infrastructure to best deliver academic courses through this medium.

  2. Age and gender interactions in short distance triathlon performance.

    PubMed

    Etter, Franziska; Knechtle, Beat; Bukowski, Arkadiusz; Rüst, Christoph Alexander; Rosemann, Thomas; Lepers, Romuald

    2013-01-01

    This study investigated the participation and performance trends as well as the age and gender interaction at the Olympic distance 'Zürich Triathlon' (1.5 km swim, 40 km cycle and 10 km run) from 2000 to 2010 in 7,939 total finishers (1,666 females and 6,273 males). Female triathletes aged from 40 to 54 years significantly (P < 0.05) increased their participation while the participation of younger females and males remained stable. Males of 50-54 years of age and females of 45-49 years of age improved their total race time. For elite top five overall triathletes, mean gender differences in swimming, cycling, running and overall race time were 15.2 ± 4.6%, 13.4 ± 2.3%, 17.1 ± 2.5%, and 14.8 ± 1.8%, respectively. For both elite and age group athletes, the gender difference in cycling time was significantly (P <0.001) lower than for swimming and running. The gender difference in overall Olympic distance triathlon performance increased after the age of 35 years, which appeared earlier compared to long distance triathlon as suggested by previous studies. Future investigations should compare gender difference in performance for different endurance events across age to confirm a possible effect of exercise duration on gender difference with advancing age.

  3. Long-distance entanglement and quantum teleportation in XX spin chains

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Campos Venuti, L.; Giampaolo, S. M.; CNR-INFM Coherentia, Napoli

    2007-11-15

    Isotropic XX models of one-dimensional spin-1/2 chains are investigated with the aim to elucidate the formal structure and the physical properties that allow these systems to act as channels for long-distance, high-fidelity quantum teleportation. We introduce two types of models: (i) open, dimerized XX chains, and (ii) open XX chains with small end bonds. For both models we obtain the exact expressions for the end-to-end correlations and the scaling of the energy gap with the length of the chain. We determine the end-to-end concurrence and show that model (i) supports true long-distance entanglement at zero temperature, while model (ii) supportsmore » 'quasi-long-distance' entanglement that slowly falls off with the size of the chain. Due to the different scalings of the gaps, respectively exponential for model (i) and algebraic in model (ii), we demonstrate that the latter allows for efficient qubit teleportation with high fidelity in sufficiently long chains even at moderately low temperatures.« less

  4. (Non-)Arguments in Long-Distance Extractions.

    PubMed

    Nyvad, Anne Mette; Kizach, Johannes; Christensen, Ken Ramshøj

    2015-10-01

    Previous research has shown that in fully grammatical sentences, response time increases and acceptability decreases when the filler in a long-distance extraction is incompatible with the matrix verb. This effect could potentially be due to a difference between argument and adjunct extraction. In this paper we investigate the effect of long extraction of arguments and adjuncts where incompatibility is kept constant. Based on the results from two offline surveys and an online experiment, we argue that the argument/adjunct asymmetry in terms of acceptability is due to differences in processing difficulty, but that both types of extraction involve the same intermediate attachment sites in the online processing.

  5. Optimal architectures for long distance quantum communication.

    PubMed

    Muralidharan, Sreraman; Li, Linshu; Kim, Jungsang; Lütkenhaus, Norbert; Lukin, Mikhail D; Jiang, Liang

    2016-02-15

    Despite the tremendous progress of quantum cryptography, efficient quantum communication over long distances (≥ 1000 km) remains an outstanding challenge due to fiber attenuation and operation errors accumulated over the entire communication distance. Quantum repeaters (QRs), as a promising approach, can overcome both photon loss and operation errors, and hence significantly speedup the communication rate. Depending on the methods used to correct loss and operation errors, all the proposed QR schemes can be classified into three categories (generations). Here we present the first systematic comparison of three generations of quantum repeaters by evaluating the cost of both temporal and physical resources, and identify the optimized quantum repeater architecture for a given set of experimental parameters for use in quantum key distribution. Our work provides a roadmap for the experimental realizations of highly efficient quantum networks over transcontinental distances.

  6. Optimal architectures for long distance quantum communication

    PubMed Central

    Muralidharan, Sreraman; Li, Linshu; Kim, Jungsang; Lütkenhaus, Norbert; Lukin, Mikhail D.; Jiang, Liang

    2016-01-01

    Despite the tremendous progress of quantum cryptography, efficient quantum communication over long distances (≥1000 km) remains an outstanding challenge due to fiber attenuation and operation errors accumulated over the entire communication distance. Quantum repeaters (QRs), as a promising approach, can overcome both photon loss and operation errors, and hence significantly speedup the communication rate. Depending on the methods used to correct loss and operation errors, all the proposed QR schemes can be classified into three categories (generations). Here we present the first systematic comparison of three generations of quantum repeaters by evaluating the cost of both temporal and physical resources, and identify the optimized quantum repeater architecture for a given set of experimental parameters for use in quantum key distribution. Our work provides a roadmap for the experimental realizations of highly efficient quantum networks over transcontinental distances. PMID:26876670

  7. Optimal architectures for long distance quantum communication

    NASA Astrophysics Data System (ADS)

    Muralidharan, Sreraman; Li, Linshu; Kim, Jungsang; Lütkenhaus, Norbert; Lukin, Mikhail D.; Jiang, Liang

    2016-02-01

    Despite the tremendous progress of quantum cryptography, efficient quantum communication over long distances (≥1000 km) remains an outstanding challenge due to fiber attenuation and operation errors accumulated over the entire communication distance. Quantum repeaters (QRs), as a promising approach, can overcome both photon loss and operation errors, and hence significantly speedup the communication rate. Depending on the methods used to correct loss and operation errors, all the proposed QR schemes can be classified into three categories (generations). Here we present the first systematic comparison of three generations of quantum repeaters by evaluating the cost of both temporal and physical resources, and identify the optimized quantum repeater architecture for a given set of experimental parameters for use in quantum key distribution. Our work provides a roadmap for the experimental realizations of highly efficient quantum networks over transcontinental distances.

  8. Long-distance electron transport occurs globally in marine sediments

    NASA Astrophysics Data System (ADS)

    Burdorf, Laurine D. W.; Tramper, Anton; Seitaj, Dorina; Meire, Lorenz; Hidalgo-Martinez, Silvia; Zetsche, Eva-Maria; Boschker, Henricus T. S.; Meysman, Filip J. R.

    2017-02-01

    Recently, long filamentous bacteria have been reported conducting electrons over centimetre distances in marine sediments. These so-called cable bacteria perform an electrogenic form of sulfur oxidation, whereby long-distance electron transport links sulfide oxidation in deeper sediment horizons to oxygen reduction in the upper millimetres of the sediment. Electrogenic sulfur oxidation exerts a strong impact on the local sediment biogeochemistry, but it is currently unknown how prevalent the process is within the seafloor. Here we provide a state-of-the-art assessment of its global distribution by combining new field observations with previous reports from the literature. This synthesis demonstrates that electrogenic sulfur oxidation, and hence microbial long-distance electron transport, is a widespread phenomenon in the present-day seafloor. The process is found in coastal sediments within different climate zones (off the Netherlands, Greenland, the USA, Australia) and thrives on a range of different coastal habitats (estuaries, salt marshes, mangroves, coastal hypoxic basins, intertidal flats). The combination of a widespread occurrence and a strong local geochemical imprint suggests that electrogenic sulfur oxidation could be an important, and hitherto overlooked, component of the marine cycle of carbon, sulfur and other elements.

  9. Bremsstrahlung versus Monoenergetic Photon Dose and Photonuclear Stimulation Comparisons at Long Standoff Distances

    NASA Astrophysics Data System (ADS)

    Jones, J. L.; Sterbentz, J. W.; Yoon, W. Y.; Norman, D. R.

    2009-12-01

    Energetic photon sources with energies greater than 6 MeV continue to be recognized as viable source for various types of inspection applications, especially those related to nuclear and/or explosive material detection. These energetic photons can be produced as a continuum of energies (i.e., bremsstrahlung) or as a set of one or more discrete photon energies (i.e., monoenergetic). This paper will provide a follow-on extension of the photon dose comparison presented at the 9th International Conference on Applications of Nuclear Techniques (June 2008). Our previous paper showed the comparative advantages and disadvantages of the photon doses provided by these two energetic interrogation sources and highlighted the higher energy advantage of the bremsstrahlung source, especially at long standoff distances (i.e., distance from source to the inspected object). This paper will pursue higher energy photon inspection advantage (up to 100 MeV) by providing dose and stimulated photonuclear interaction predictions in air and for an infinitely dilute interrogated material (used for comparative interaction rate assessments since it excludes material self-shielding) as the interrogation object positioned forward on the inspection beam axis at increasing standoff distances. In addition to the direct energetic photon-induced stimulation, the predictions will identify the importance of secondary downscattered/attenuated source-term effects arising from the photon transport in the intervening air environment.

  10. Effective Affective Design for Distance Education.

    ERIC Educational Resources Information Center

    Zvacek, Susan M.

    1991-01-01

    Discusses the importance of affective considerations when designing instruction for distance education. Topics discussed include learner motivation based on Keller's ARCS model (Attention, Relevance, Confidence, and Satisfaction); communication patterns that facilitate interaction between students; and ethics involved with marketing programs,…

  11. Progesterone stimulates the long-distance migration of capacitated ram spermatozoa through viscous media under geotactic condition.

    PubMed

    Martínez-Rodríguez, Carmen; Anel-López, Luis; Alvarez, Mercedes; Ortega-Ferrusola, Cristina; Boixo, Juan Carlos; Peña, Fernando J; Anel, Luis; de Paz, Paulino

    2018-05-15

    Forward progressive motility of spermatozoa is an essential prerequisite for reproductive success, and sperm navigation is assisted by guidance mechanisms that may depend on micro-environmental factors. In the present study, we performed an integrated analysis of long-distance ram sperm migration in vitro that combined two environmental factors (10 μM progesterone and a geotactic effect) and the physiological status of the cells (capacitation treatment). A penetration assay was used in which spermatozoa had to travel 20 mm in a viscous medium (two media of differing viscosity: acrylamide and hyaluronic acid) through a tube device. The number of migrating spermatozoa, the physiology of the cells (motility analyzed using a CASA system; acrosomal status, viability and active mitochondria evaluated by flow cytometry; DNA fragmentation index calculated by quantitative PCR) and the morphometry of sperm heads (performed using an image analysis system) were evaluated after long-distance sperm migration. Ram sperm capacitation significantly stimulates cell migration through viscous media under geotactic conditions, and this effect is enhanced by progesterone induction. The rheological characteristics of viscous media have a marked impact on ram sperm migration, and acrylamide more favorably facilitates navigation over a large distance. The migrating spermatozoa are morphologically better adapted (high ellipticity) for displacement in viscous media and exhibit remarkably depleted mitochondrial membrane potential. Copyright © 2018 Elsevier Inc. All rights reserved.

  12. Development of a Framework for Guiding Interaction Design in Distance Learning

    ERIC Educational Resources Information Center

    Li, Wei

    2015-01-01

    As one of the most critical elements in distance learning, interaction has been identified empirically as increasing learner motivation, satisfaction, participation, communication, and achievement. Fostering pedagogically effective interaction is a major challenge for educators in distance learning. In response to this challenge, the goal of this…

  13. [Evolutionary history of human locomotor system--from walking to long-distance running].

    PubMed

    Viranta-Kovanen, Suvi

    2015-01-01

    Bipedality evolved in hominids more than 4 million years ago. Bipedals were a diverse group including the lineage of obligatory walkers that finally lead to humans. Important anatomical changes in this group were: enhanced lumbar lordosis, shortening of the ilium, and emphasize on the parasagittal movements. Long-distance running evolved much later and it was associated with well-developed plantar arches, strengthening of muscles supporting the erect trunk, and decoupling of the pectoral girdle and head. In addition to anatomical changes, humans have many physiological adaptations to long-distance running. It is likely that the ability to run long-distance has been important for the survival of our species.

  14. The Evolution of Distance Learning: Technology-Mediated Interactive Learning.

    ERIC Educational Resources Information Center

    Dede, Christopher J.

    1990-01-01

    Summarizes a paper prepared for the Office of Technology Assessment (OTA) on the evolution of distance learning which begins by describing technological, the demographic, economic, political, and pedagogical forces involved. A new field is proposed called technology-mediated interactive learning (TMIL), which synthesizes distance learning,…

  15. Increased Prevalence of the IL-6-174C Genetic Polymorphism in Long Distance Swimmers.

    PubMed

    Ben-Zaken, Sigal; Meckel, Yoav; Nemet, Dan; Kassem, Eias; Eliakim, Alon

    2017-09-01

    The IL-6 -174G/C single nucleotide polymorphism (SNP) functionally affects IL-6 activity, with the G-allele associated with increased IL-6 levels. The C-allele was found to be associated with exercise-induced skeletal muscle damage. The aim of the present study was to examine the association between the IL-6 -174G/C polymorphism and athletic performance among elite swimmers and runners. The study sample included 180 track and field athletes and 80 swimmers. Track and field athletes were assigned to three sub-groups: long-distance runners, middle-distance runners and short-distance runners. Swimmers were assigned to two subgroups: long-distance swimmers and short-distance swimmers. The control group consisted of 123 non-athletic healthy individuals. Genomic DNA was extracted from peripheral blood following a standard protocol. Genotyping was performed using polymerase chain reaction (PCR). The CC genotype and C-allele frequency were significantly higher in the long-distance swimmers (18 and 43%, respectively) compared to the long-distance runners (3 and 14%, respectively, p < 0.001); middle-distance runners (4 and 22%, respectively, p < 0.001); and controls (5 and 19%, respectively, p < 0.001). In addition, the CC genotype and C-allele frequency were significantly higher (p < 0.001) in long-distance swimmers compared to short-distance swimmers (18 versus 5% and 43 versus 29% for the CC genotype and C-allele frequency, respectively). The higher frequency of the C-allele and CC genotype among long-distance swimmers suggests that the rarity of exercise-associated rhabdomyolysis among swimmers is probably related to other sports-specific or water-related protective mechanisms. It is possible that swimming selection in talented endurance athletes who are C-allele carriers represents an example of genetically-dependent sports selection.

  16. Increased Prevalence of the IL-6-174C Genetic Polymorphism in Long Distance Swimmers

    PubMed Central

    Ben-Zaken, Sigal; Meckel, Yoav; Nemet, Dan; Kassem, Eias; Eliakim, Alon

    2017-01-01

    Abstract The IL-6 -174G/C single nucleotide polymorphism (SNP) functionally affects IL-6 activity, with the G-allele associated with increased IL-6 levels. The C-allele was found to be associated with exercise-induced skeletal muscle damage. The aim of the present study was to examine the association between the IL-6 -174G/C polymorphism and athletic performance among elite swimmers and runners. The study sample included 180 track and field athletes and 80 swimmers. Track and field athletes were assigned to three sub-groups: long-distance runners, middle-distance runners and short-distance runners. Swimmers were assigned to two subgroups: long-distance swimmers and short-distance swimmers. The control group consisted of 123 non-athletic healthy individuals. Genomic DNA was extracted from peripheral blood following a standard protocol. Genotyping was performed using polymerase chain reaction (PCR). The CC genotype and C-allele frequency were significantly higher in the long-distance swimmers (18 and 43%, respectively) compared to the long-distance runners (3 and 14%, respectively, p < 0.001); middle-distance runners (4 and 22%, respectively, p < 0.001); and controls (5 and 19%, respectively, p < 0.001). In addition, the CC genotype and C-allele frequency were significantly higher (p < 0.001) in long-distance swimmers compared to short-distance swimmers (18 versus 5% and 43 versus 29% for the CC genotype and C-allele frequency, respectively). The higher frequency of the C-allele and CC genotype among long-distance swimmers suggests that the rarity of exercise-associated rhabdomyolysis among swimmers is probably related to other sports-specific or water-related protective mechanisms. It is possible that swimming selection in talented endurance athletes who are C-allele carriers represents an example of genetically-dependent sports selection. PMID:28828083

  17. Common Leg Injuries of Long-Distance Runners

    PubMed Central

    Gallo, Robert A.; Plakke, Michael; Silvis, Matthew L.

    2012-01-01

    Context Long-distance running (greater than 3000 m) is often recommended to maintain a healthy lifestyle. Running injury rates increase significantly when weekly mileage extends beyond 40 miles cumulatively. With the development of running analysis and other diagnostic tests, injuries to the leg secondary to bone, musculotendinous, and vascular causes can be diagnosed and successfully managed. Evidence Acquisition Searches used the terms running, injuries, lower extremity, leg, medial tibial stress syndrome, compartment syndrome, stress fractures, popliteal artery entrapment, gastrocnemius soleus tears, and Achilles tendinopathy. Sources included Medline, Google Scholar, and Ovid from 1970 through January 2012. Results Tibial stress fractures and medial tibial stress syndrome can sometimes be prevented and/or treated by correcting biomechanical abnormalities. Exertional compartment syndrome and popliteal artery entrapment syndrome are caused by anatomic abnormalities and are difficult to treat without surgical correction. Conclusion Leg pain due to bone, musculotendinous, and vascular causes is common among long-distance runners. Knowledge of the underlying biomechanical and/or anatomic abnormality is necessary to successfully treat these conditions. PMID:24179587

  18. Florida long-distance travel characteristics and their potential impacts on the transportation system.

    DOT National Transportation Integrated Search

    2013-03-01

    The overall goal of this project is to enhance the fundamental understanding of Florida long-distance travel characteristics, and to provide policy implications for long-distance transportation planning in the future. To achieve the research goal, th...

  19. 47 CFR 32.5100 - Long distance message revenue.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 2 2014-10-01 2014-10-01 false Long distance message revenue. 32.5100 Section 32.5100 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES UNIFORM SYSTEM OF ACCOUNTS FOR TELECOMMUNICATIONS COMPANIES Instructions For Revenue Accounts § 32.5100...

  20. 47 CFR 32.5100 - Long distance message revenue.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 2 2011-10-01 2011-10-01 false Long distance message revenue. 32.5100 Section 32.5100 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES UNIFORM SYSTEM OF ACCOUNTS FOR TELECOMMUNICATIONS COMPANIES Instructions For Revenue Accounts § 32.5100...

  1. Interactive Distance Learning Effectively Provides Winning Sports Nutrition Workshops.

    ERIC Educational Resources Information Center

    Ricketts, Jennifer; Hoelscher-Day, Sharon; Begeman, Gale; Houtkooper, Linda

    2001-01-01

    Interactive distance-education (n=226) and face-to-face (n=129) continuing education workshops for health care and education professionals on sports nutrition were evaluated immediately and after 6 months. The well-designed distance-education format was as effective and acceptable as face to face and increased sports nutrition knowledge. (SK)

  2. Nonlinear Gap Junctions Enable Long-Distance Propagation of Pulsating Calcium Waves in Astrocyte Networks

    PubMed Central

    Goldberg, Mati; De Pittà, Maurizio; Volman, Vladislav; Berry, Hugues; Ben-Jacob, Eshel

    2010-01-01

    A new paradigm has recently emerged in brain science whereby communications between glial cells and neuron-glia interactions should be considered together with neurons and their networks to understand higher brain functions. In particular, astrocytes, the main type of glial cells in the cortex, have been shown to communicate with neurons and with each other. They are thought to form a gap-junction-coupled syncytium supporting cell-cell communication via propagating Ca2+ waves. An identified mode of propagation is based on cytoplasm-to-cytoplasm transport of inositol trisphosphate (IP3) through gap junctions that locally trigger Ca2+ pulses via IP3-dependent Ca2+-induced Ca2+ release. It is, however, currently unknown whether this intracellular route is able to support the propagation of long-distance regenerative Ca2+ waves or is restricted to short-distance signaling. Furthermore, the influence of the intracellular signaling dynamics on intercellular propagation remains to be understood. In this work, we propose a model of the gap-junctional route for intercellular Ca2+ wave propagation in astrocytes. Our model yields two major predictions. First, we show that long-distance regenerative signaling requires nonlinear coupling in the gap junctions. Second, we show that even with nonlinear gap junctions, long-distance regenerative signaling is favored when the internal Ca2+ dynamics implements frequency modulation-encoding oscillations with pulsating dynamics, while amplitude modulation-encoding dynamics tends to restrict the propagation range. As a result, spatially heterogeneous molecular properties and/or weak couplings are shown to give rise to rich spatiotemporal dynamics that support complex propagation behaviors. These results shed new light on the mechanisms implicated in the propagation of Ca2+ waves across astrocytes and the precise conditions under which glial cells may participate in information processing in the brain. PMID:20865153

  3. Formation of virions is strictly required for turnip yellows virus long-distance movement in plants.

    PubMed

    Hipper, Clémence; Monsion, Baptiste; Bortolamiol-Bécet, Diane; Ziegler-Graff, Véronique; Brault, Véronique

    2014-02-01

    Viral genomic RNA of the Turnip yellows virus (TuYV; genus Polerovirus; family Luteoviridae) is protected in virions formed by the major capsid protein (CP) and the minor component, the readthrough (RT*) protein. Long-distance transport, used commonly by viruses to systemically infect host plants, occurs in phloem sieve elements and two viral forms of transport have been described: virions and ribonucleoprotein (RNP) complexes. With regard to poleroviruses, virions have always been presumed to be the long-distance transport form, but the potential role of RNP complexes has not been investigated. Here, we examined the requirement of virions for polerovirus systemic movement by analysing CP-targeted mutants that were unable to form viral particles. We confirmed that TuYV mutants that cannot encapsidate into virions are not able to reach systemic leaves. To completely discard the possibility that the introduced mutations in CP simply blocked the formation or the movement of RNP complexes, we tested in trans complementation of TuYV CP mutants by providing WT CP expressed in transgenic plants. WT CP was able to facilitate systemic movement of TuYV CP mutants and this observation was always correlated with the formation of virions. This demonstrated clearly that virus particles are essential for polerovirus systemic movement.

  4. Fast Quantum State Transfer and Entanglement Renormalization Using Long-Range Interactions.

    PubMed

    Eldredge, Zachary; Gong, Zhe-Xuan; Young, Jeremy T; Moosavian, Ali Hamed; Foss-Feig, Michael; Gorshkov, Alexey V

    2017-10-27

    In short-range interacting systems, the speed at which entanglement can be established between two separated points is limited by a constant Lieb-Robinson velocity. Long-range interacting systems are capable of faster entanglement generation, but the degree of the speedup possible is an open question. In this Letter, we present a protocol capable of transferring a quantum state across a distance L in d dimensions using long-range interactions with a strength bounded by 1/r^{α}. If αdistance L; if d<αinteractions in three dimensions.

  5. Fast Quantum State Transfer and Entanglement Renormalization Using Long-Range Interactions

    NASA Astrophysics Data System (ADS)

    Eldredge, Zachary; Gong, Zhe-Xuan; Young, Jeremy T.; Moosavian, Ali Hamed; Foss-Feig, Michael; Gorshkov, Alexey V.

    2017-10-01

    In short-range interacting systems, the speed at which entanglement can be established between two separated points is limited by a constant Lieb-Robinson velocity. Long-range interacting systems are capable of faster entanglement generation, but the degree of the speedup possible is an open question. In this Letter, we present a protocol capable of transferring a quantum state across a distance L in d dimensions using long-range interactions with a strength bounded by 1 /rα. If α distance L ; if d <α interactions in three dimensions.

  6. Characteristics of lesser prairie-chicken (Tympanuchus pallidicinctus) long-distance movements across their distribution

    USGS Publications Warehouse

    Earl, Julia E.; Fuhlendorf, Samuel D.; Haukos, David A.; Tanner, Ashley M.; Elmore, Dwayne; Carleton, Scott A.

    2016-01-01

    Long-distance movements are important adaptive behaviors that contribute to population, community, and ecosystem connectivity. However, researchers have a poor understanding of the characteristics of long-distance movements for most species. Here, we examined long-distance movements for the lesser prairie-chicken (Tympanuchus pallidicinctus), a species of conservation concern. We addressed the following questions: (1) At what distances could populations be connected? (2) What are the characteristics and probability of dispersal movements? (3) Do lesser prairie-chickens display exploratory and round-trip movements? (4) Do the characteristics of long-distance movements vary by site? Movements were examined from populations using satellite GPS transmitters across the entire distribution of the species in New Mexico, Oklahoma, Kansas, and Colorado. Dispersal movements were recorded up to 71 km net displacement, much farther than hitherto recorded. These distances suggest that there may be greater potential connectivity among populations than previously thought. Dispersal movements were displayed primarily by females and had a northerly directional bias. Dispersal probabilities ranged from 0.08 to 0.43 movements per year for both sexes combined, although these movements averaged only 16 km net displacement. Lesser prairie-chickens displayed both exploratory foray loops and round-trip movements. Half of round-trip movements appeared seasonal, suggesting a partial migration in some populations. None of the long-distance movements varied by study site. Data presented here will be important in parameterizing models assessing population viability and informing conservation planning, although further work is needed to identify landscape features that may reduce connectivity among populations.

  7. Long-distance transport of phytohormones through the plant vascular system.

    PubMed

    Lacombe, Benoit; Achard, Patrick

    2016-12-01

    Phytohormones are a group of low abundance molecules that activate various metabolic and developmental processes in response to environmental and endogenous signals. Like animal hormones, plant hormones often have distinct source and target tissues, hence ensuring long-range communication at the whole-plant level. Plants rely on various hormone distribution mechanisms depending on the distance and the direction of the transport. Here, we highlight the recent findings on the long-distance movement of plant hormones within the vasculature, from the physiological role to the molecular mechanism of the transport. Copyright © 2016 Elsevier Ltd. All rights reserved.

  8. Long-distance super-resolution imaging assisted by enhanced spatial Fourier transform.

    PubMed

    Tang, Heng-He; Liu, Pu-Kun

    2015-09-07

    A new gradient-index (GRIN) lens that can realize enhanced spatial Fourier transform (FT) over optically long distances is demonstrated. By using an anisotropic GRIN metamaterial with hyperbolic dispersion, evanescent wave in free space can be transformed into propagating wave in the metamaterial and then focused outside due to negative-refraction. Both the results based on the ray tracing and the finite element simulation show that the spatial frequency bandwidth of the spatial FT can be extended to 2.7k(0) (k(0) is the wave vector in free space). Furthermore, assisted by the enhanced spatial FT, a new long-distance (in the optical far-field region) super-resolution imaging scheme is also proposed and the super resolved capability of λ/5 (λ is the wavelength in free space) is verified. The work may provide technical support for designing new-type high-speed microscopes with long working distances.

  9. Long distance quantum teleportation in a quantum relay configuration.

    PubMed

    de Riedmatten, H; Marcikic, I; Tittel, W; Zbinden, H; Collins, D; Gisin, N

    2004-01-30

    A long distance quantum teleportation experiment with a fiber-delayed Bell state measurement (BSM) is reported. The source creating the qubits to be teleported and the source creating the necessary entangled state are connected to the beam splitter realizing the BSM by two 2 km long optical fibers. In addition, the teleported qubits are analyzed after 2.2 km of optical fiber, in another laboratory separated by 55 m. Time-bin qubits carried by photons at 1310 nm are teleported onto photons at 1550 nm. The fidelity is of 77%, above the maximal value obtainable without entanglement. This is the first realization of an elementary quantum relay over significant distances, which will allow an increase in the range of quantum communication and quantum key distribution.

  10. Long-distance continuous-variable quantum key distribution by controlling excess noise

    NASA Astrophysics Data System (ADS)

    Huang, Duan; Huang, Peng; Lin, Dakai; Zeng, Guihua

    2016-01-01

    Quantum cryptography founded on the laws of physics could revolutionize the way in which communication information is protected. Significant progresses in long-distance quantum key distribution based on discrete variables have led to the secure quantum communication in real-world conditions being available. However, the alternative approach implemented with continuous variables has not yet reached the secure distance beyond 100 km. Here, we overcome the previous range limitation by controlling system excess noise and report such a long distance continuous-variable quantum key distribution experiment. Our result paves the road to the large-scale secure quantum communication with continuous variables and serves as a stepping stone in the quest for quantum network.

  11. Long-distance continuous-variable quantum key distribution by controlling excess noise.

    PubMed

    Huang, Duan; Huang, Peng; Lin, Dakai; Zeng, Guihua

    2016-01-13

    Quantum cryptography founded on the laws of physics could revolutionize the way in which communication information is protected. Significant progresses in long-distance quantum key distribution based on discrete variables have led to the secure quantum communication in real-world conditions being available. However, the alternative approach implemented with continuous variables has not yet reached the secure distance beyond 100 km. Here, we overcome the previous range limitation by controlling system excess noise and report such a long distance continuous-variable quantum key distribution experiment. Our result paves the road to the large-scale secure quantum communication with continuous variables and serves as a stepping stone in the quest for quantum network.

  12. Long-distance continuous-variable quantum key distribution by controlling excess noise

    PubMed Central

    Huang, Duan; Huang, Peng; Lin, Dakai; Zeng, Guihua

    2016-01-01

    Quantum cryptography founded on the laws of physics could revolutionize the way in which communication information is protected. Significant progresses in long-distance quantum key distribution based on discrete variables have led to the secure quantum communication in real-world conditions being available. However, the alternative approach implemented with continuous variables has not yet reached the secure distance beyond 100 km. Here, we overcome the previous range limitation by controlling system excess noise and report such a long distance continuous-variable quantum key distribution experiment. Our result paves the road to the large-scale secure quantum communication with continuous variables and serves as a stepping stone in the quest for quantum network. PMID:26758727

  13. Thermal transport in the Fermi-Pasta-Ulam model with long-range interactions

    NASA Astrophysics Data System (ADS)

    Bagchi, Debarshee

    2017-03-01

    We study the thermal transport properties of the one-dimensional Fermi-Pasta-Ulam model (β type) with long-range interactions. The strength of the long-range interaction decreases with the (shortest) distance between the lattice sites as distance-δ, where δ ≥0 . Two Langevin heat baths at unequal temperatures are connected to the ends of the one-dimensional lattice via short-range harmonic interactions that drive the system away from thermal equilibrium. In the nonequilibrium steady state the heat current, thermal conductivity, and temperature profiles are computed by solving the equations of motion numerically. It is found that the conductivity κ has an interesting nonmonotonic dependence with δ with a maximum at δ =2.0 for this model. Moreover, at δ =2.0 ,κ diverges almost linearly with system size N and the temperature profile has a negligible slope, as one expects in ballistic transport for an integrable system. We demonstrate that the nonmonotonic behavior of the conductivity and the nearly ballistic thermal transport at δ =2.0 obtained under nonequilibrium conditions can be explained consistently by studying the variation of largest Lyapunov exponent λmax with δ , and excess energy diffusion in the equilibrium microcanonical system.

  14. Commitment Predictors: Long-Distance versus Geographically Close Relationships

    ERIC Educational Resources Information Center

    Pistole, M. Carole; Roberts, Amber; Mosko, Jonathan E.

    2010-01-01

    In this web-based study, the authors examined long-distance relationships (LDRs) and geographically close relationships (GCRs). Two hierarchical multiple regressions (N = 138) indicated that attachment predicted LDR and GCR commitment in Step 1. Final equations indicated that high satisfaction and investments predicted LDR commitment, whereas low…

  15. Scanning optical microscope with long working distance objective

    DOEpatents

    Cloutier, Sylvain G.

    2010-10-19

    A scanning optical microscope, including: a light source to generate a beam of probe light; collimation optics to substantially collimate the probe beam; a probe-result beamsplitter; a long working-distance, infinity-corrected objective; scanning means to scan a beam spot of the focused probe beam on or within a sample; relay optics; and a detector. The collimation optics are disposed in the probe beam. The probe-result beamsplitter is arranged in the optical paths of the probe beam and the resultant light from the sample. The beamsplitter reflects the probe beam into the objective and transmits resultant light. The long working-distance, infinity-corrected objective is also arranged in the optical paths of the probe beam and the resultant light. It focuses the reflected probe beam onto the sample, and collects and substantially collimates the resultant light. The relay optics are arranged to relay the transmitted resultant light from the beamsplitter to the detector.

  16. Humid microclimates within the plumage of mallard ducks (Anas platyrhynchos) can potentially facilitate long distance dispersal of propagules

    NASA Astrophysics Data System (ADS)

    Coughlan, Neil E.; Kelly, Tom C.; Davenport, John; Jansen, Marcel A. K.

    2015-05-01

    Birds as carriers of propagules are major agents in the dispersal of plants, animals, fungi and microbes. However, there is a lack of empirical data in relation to bird-mediated, epizoochorous dispersal. The microclimate found within the plumage likely plays a pivotal role in survival during flight conditions. To investigate the potential of epizoochory, we have analysed the microclimatic conditions within the plumage of mallard ducks (Anas platyrhynchos). Under similar ambient conditions of humidity and temperature, a sample of mallards showed a consistent microclimatic regime with variation across the body surface. The highest (mean) temperature and specific humidity occurred between feathers of the postpatagium. The lowest humidity was found between feathers of the centre back and the lowest temperature in the crissum. Observed differences in plumage depth and density, and distance from the skin, are all likely to be determining factors of microclimate condition. Specific humidity found within the plumage was on average 1.8-3.5 times greater than ambient specific humidity. Thus, the plumage can supply a microclimate buffered from that of the exterior environment. Extrapolating survival data for Lemna minor desiccation at various temperature and humidity levels to the measured plumage microclimatic conditions of living birds, survival for up to 6 h can be anticipated, especially in crissum, crural and breast plumage. The results are discussed in the context of potential long distance epizoochorous dispersal by A. platyrhynchos and similar species.

  17. Education on the Electronic Frontier: Teleapprentices in Globally Distributed Educational Contexts. Interactive Technology Laboratory Report #14.

    ERIC Educational Resources Information Center

    Levin, James A.; And Others

    1987-01-01

    The instructional media created by microcomputers interconnected by modems to form long-distance networks present some powerful new opportunities for education. While other uses of computers in education have been built on conventional instructional models of classroom interaction, instructional electronic networks facilitate a wider use of…

  18. Viterbi equalization for long-distance, high-speed underwater laser communication

    NASA Astrophysics Data System (ADS)

    Hu, Siqi; Mi, Le; Zhou, Tianhua; Chen, Weibiao

    2017-07-01

    In long-distance, high-speed underwater laser communication, because of the strong absorption and scattering processes, the laser pulse is stretched with the increase in communication distance and the decrease in water clarity. The maximum communication bandwidth is limited by laser-pulse stretching. Improving the communication rate increases the intersymbol interference (ISI). To reduce the effect of ISI, the Viterbi equalization (VE) algorithm is used to estimate the maximum-likelihood receiving sequence. The Monte Carlo method is used to simulate the stretching of the received laser pulse and the maximum communication rate at a wavelength of 532 nm in Jerlov IB and Jerlov II water channels with communication distances of 80, 100, and 130 m, respectively. The high-data rate communication performance for the VE and hard-decision algorithms is compared. The simulation results show that the VE algorithm can be used to reduce the ISI by selecting the minimum error path. The trade-off between the high-data rate communication performance and minor bit-error rate performance loss makes VE a promising option for applications in long-distance, high-speed underwater laser communication systems.

  19. Spread of Correlations in Long-Range Interacting Quantum Systems

    NASA Astrophysics Data System (ADS)

    Hauke, P.; Tagliacozzo, L.

    2013-11-01

    The nonequilibrium response of a quantum many-body system defines its fundamental transport properties and how initially localized quantum information spreads. However, for long-range-interacting quantum systems little is known. We address this issue by analyzing a local quantum quench in the long-range Ising model in a transverse field, where interactions decay as a variable power law with distance ∝r-α, α>0. Using complementary numerical and analytical techniques, we identify three dynamical regimes: short-range-like with an emerging light cone for α>2, weakly long range for 1<α<2 without a clear light cone but with a finite propagation speed of almost all excitations, and fully nonlocal for α<1 with instantaneous transmission of correlations. This last regime breaks generalized Lieb-Robinson bounds and thus locality. Numerical calculation of the entanglement spectrum demonstrates that the usual picture of propagating quasiparticles remains valid, allowing an intuitive interpretation of our findings via divergences of quasiparticle velocities. Our results may be tested in state-of-the-art trapped-ion experiments.

  20. Interactive Distance Education: A Cognitive Load Perspective

    ERIC Educational Resources Information Center

    Kalyuga, Slava

    2012-01-01

    Evidence-based approaches to the design of the next generation of interactive distance education need to take into account established multimedia learning principles. Cognitive load theory is a theory that has significantly contributed to the development of such principles. It has applied our knowledge of major features and processing limitations…

  1. Accessible Adult Learning in the Health Professions: Interactive Uses of Distance Technology.

    ERIC Educational Resources Information Center

    Townsend, Elizabeth; Curran-Smith, Janet

    This paper describes a study of students' perceptions of the impact of accessibility and interactivity on successful distance education in the Health Professions. The study utilized both quantitative and qualitative data to determine how students perceived issues of accessibility and interactivity affecting their success in distance courses. The…

  2. Characterization of Long Working Distance Optical Coherence Tomography for Imaging of Pediatric Retinal Pathology.

    PubMed

    Qian, Ruobing; Carrasco-Zevallos, Oscar M; Mangalesh, Shwetha; Sarin, Neeru; Vajzovic, Lejla; Farsiu, Sina; Izatt, Joseph A; Toth, Cynthia A

    2017-10-01

    We determined the feasibility of fovea and optic nerve head imaging with a long working distance (LWD) swept source optical coherence tomography (OCT) prototype in adults, teenagers, and young children. A prototype swept source OCT system with a LWD (defined as distance from the last optical element of the imaging system to the eye) of 350 mm with custom fixation targets was developed to facilitate imaging of children. Imaging was performed in 49 participants from three age groups: 26 adults, 16 children 13 to 18 years old (teenagers), and seven children under 6 years old (young children) under an approved institutional review board protocol. The imaging goal was to acquire high quality scans of the fovea and optic nerve in each eye in the shortest time possible. OCT B-scans and volumes of the fovea and optic nerve head of each eligible eye were captured and graded based on four categories (lateral and axial centration, contrast, and resolution) and on ability to determine presence or absence of pathology. LWD-OCT imaging was successful in 88 of 94 eligible eyes, including seven of 10 eyes of young children. Of the successfully acquired OCT images, 83% of B-scan and volumetric images, including 86% from young children, were graded as high-quality scans. Pathology was observed in high-quality OCT images. The prototype LWD-OCT system achieved high quality retinal imaging of adults, teenagers, and some young children with and without pathology with reasonable alignment time. The LWD-OCT system can facilitate imaging in children.

  3. Characterization of Long Working Distance Optical Coherence Tomography for Imaging of Pediatric Retinal Pathology

    PubMed Central

    Qian, Ruobing; Carrasco-Zevallos, Oscar M.; Mangalesh, Shwetha; Sarin, Neeru; Vajzovic, Lejla; Farsiu, Sina; Izatt, Joseph A.; Toth, Cynthia A.

    2017-01-01

    Purpose We determined the feasibility of fovea and optic nerve head imaging with a long working distance (LWD) swept source optical coherence tomography (OCT) prototype in adults, teenagers, and young children. Methods A prototype swept source OCT system with a LWD (defined as distance from the last optical element of the imaging system to the eye) of 350 mm with custom fixation targets was developed to facilitate imaging of children. Imaging was performed in 49 participants from three age groups: 26 adults, 16 children 13 to 18 years old (teenagers), and seven children under 6 years old (young children) under an approved institutional review board protocol. The imaging goal was to acquire high quality scans of the fovea and optic nerve in each eye in the shortest time possible. OCT B-scans and volumes of the fovea and optic nerve head of each eligible eye were captured and graded based on four categories (lateral and axial centration, contrast, and resolution) and on ability to determine presence or absence of pathology. Results LWD-OCT imaging was successful in 88 of 94 eligible eyes, including seven of 10 eyes of young children. Of the successfully acquired OCT images, 83% of B-scan and volumetric images, including 86% from young children, were graded as high-quality scans. Pathology was observed in high-quality OCT images. Conclusions The prototype LWD-OCT system achieved high quality retinal imaging of adults, teenagers, and some young children with and without pathology with reasonable alignment time. Translational Relevance The LWD-OCT system can facilitate imaging in children. PMID:29057163

  4. Humans as long-distance dispersers of rural plant communities.

    PubMed

    Auffret, Alistair G; Cousins, Sara A O

    2013-01-01

    Humans are known for their capacity to disperse organisms long distances. Long-distance dispersal can be important for species threatened by habitat destruction, but research into human-mediated dispersal is often focused upon few and/or invasive species. Here we use citizen science to identify the capacity for humans to disperse seeds on their clothes and footwear from a known species pool in a valuable habitat, allowing for an assessment of the fraction and types of species dispersed by humans in an alternative context. We collected material from volunteers cutting 48 species-rich meadows throughout Sweden. We counted 24,354 seeds of 197 species, representing 34% of the available species pool, including several rare and protected species. However, 71 species (36%) are considered invasive elsewhere in the world. Trait analysis showed that seeds with hooks or other appendages were more likely to be dispersed by humans, as well as those with a persistent seed bank. More activity in a meadow resulted in more dispersal, both in terms of species and representation of the source communities. Average potential dispersal distances were measured at 13 km. We consider humans capable seed dispersers, transporting a significant proportion of the plant communities in which they are active, just like more traditional vectors such as livestock. When rural populations were larger, people might have been regular and effective seed dispersers, and the net rural-urban migration resulting in a reduction in humans in the landscape may have exacerbated the dispersal failure evident in declining plant populations today. With the fragmentation of habitat and changes in land use resulting from agricultural change, and the increased mobility of humans worldwide, the dispersal role of humans may have shifted from providers of regular local and landscape dispersal to providers of much rarer long-distance and regional dispersal, and international invasion.

  5. Long-distance quantum communication over noisy networks without long-time quantum memory

    NASA Astrophysics Data System (ADS)

    Mazurek, Paweł; Grudka, Andrzej; Horodecki, Michał; Horodecki, Paweł; Łodyga, Justyna; Pankowski, Łukasz; PrzysieŻna, Anna

    2014-12-01

    The problem of sharing entanglement over large distances is crucial for implementations of quantum cryptography. A possible scheme for long-distance entanglement sharing and quantum communication exploits networks whose nodes share Einstein-Podolsky-Rosen (EPR) pairs. In Perseguers et al. [Phys. Rev. A 78, 062324 (2008), 10.1103/PhysRevA.78.062324] the authors put forward an important isomorphism between storing quantum information in a dimension D and transmission of quantum information in a D +1 -dimensional network. We show that it is possible to obtain long-distance entanglement in a noisy two-dimensional (2D) network, even when taking into account that encoding and decoding of a state is exposed to an error. For 3D networks we propose a simple encoding and decoding scheme based solely on syndrome measurements on 2D Kitaev topological quantum memory. Our procedure constitutes an alternative scheme of state injection that can be used for universal quantum computation on 2D Kitaev code. It is shown that the encoding scheme is equivalent to teleporting the state, from a specific node into a whole two-dimensional network, through some virtual EPR pair existing within the rest of network qubits. We present an analytic lower bound on fidelity of the encoding and decoding procedure, using as our main tool a modified metric on space-time lattice, deviating from a taxicab metric at the first and the last time slices.

  6. Evaluation of Distance Course Effectiveness - Exploring the Quality of Interactive Processes

    NASA Astrophysics Data System (ADS)

    Botelho, Francisco Villa Ulhôa; Vicari, Rosa Maria

    Understanding the dynamics of learning processes implies an understanding of their components: individuals, environment or context and mediation. It is known that distance learning (DL) has a distinctive characteristic in relation to the mediation component. Due to the need of overcoming the barriers of distance and time, DL intensively uses information and communication technologies (ICT) to perform interactive processes. Construction of effective learning environments depends on human relationships. It also depends on the emotionality placed on such relationships. Therefore, knowing how to act in virtual environments in the sense of creating the required ambiance for animation of learning processes has a unique importance. This is the theme of this study. Its general objectives were achieved and can be summarized as follows: analyze indexes that are significant for evaluations of distance course effectiveness; investigate to which extent effectiveness of DL courses is correlated with quality of interactive processes; search characteristics of the conversations by individuals interacting in study groups that are formed in virtual environments, which may contribute to effectiveness of distance courses.

  7. Conflicting evidence about long-distance animal navigation.

    PubMed

    Alerstam, Thomas

    2006-08-11

    Because of conflicting evidence about several fundamental issues, long-distance animal navigation has yet to be satisfactorily explained. Among the unsolved problems are the nature of genetic spatial control of migration and the relationships between celestial and magnetic compass mechanisms and between different map-related cues in orientation and homing, respectively. In addition, navigation is expected to differ between animal groups depending on sensory capabilities and ecological conditions. Evaluations based on modern long-term tracking techniques of the geometry of migration routes and individual migration history, combined with behavioral experiments and exploration of the sensory and genetic mechanisms, will be crucial for understanding the spatial principles that guide animals on their global journeys.

  8. 3. Credit JTL Long distance view looking upstream towards New ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Credit JTL Long distance view looking upstream towards New Hampshire; commercial structures in foreground. - Bellows Falls Arch Bridge, Spanning Connecticut River, North Walpole, Cheshire County, NH

  9. Moving Large Data Sets Over High-Performance Long Distance Networks

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hodson, Stephen W; Poole, Stephen W; Ruwart, Thomas

    2011-04-01

    In this project we look at the performance characteristics of three tools used to move large data sets over dedicated long distance networking infrastructure. Although performance studies of wide area networks have been a frequent topic of interest, performance analyses have tended to focus on network latency characteristics and peak throughput using network traffic generators. In this study we instead perform an end-to-end long distance networking analysis that includes reading large data sets from a source file system and committing large data sets to a destination file system. An evaluation of end-to-end data movement is also an evaluation of themore » system configurations employed and the tools used to move the data. For this paper, we have built several storage platforms and connected them with a high performance long distance network configuration. We use these systems to analyze the capabilities of three data movement tools: BBcp, GridFTP, and XDD. Our studies demonstrate that existing data movement tools do not provide efficient performance levels or exercise the storage devices in their highest performance modes. We describe the device information required to achieve high levels of I/O performance and discuss how this data is applicable in use cases beyond data movement performance.« less

  10. Necessity Fuels Creativity: Adapting Long-Distance Collaborative Methods for the Classroom

    ERIC Educational Resources Information Center

    Sopoci Drake, Katie; Larson, Eliza; Rugh, Rachel; Tait, Barbara

    2016-01-01

    Improved technology has made it possible to virtually bridge distance between dance makers, rendering physical location another choreographic device to be manipulated. Long-distance collaboration as an artistic process is not only a fertile new ground for creation and necessary for many practicing dance artists in the field today, but there is…

  11. Testing spatial theories of plant coexistence: no consistent differences in intra- and interspecific interaction distances.

    PubMed

    Vogt, Deborah R; Murrell, David J; Stoll, Peter

    2010-01-01

    Plants stand still and interact with their immediate neighbors. Theory has shown that the distances over which these interactions occur may have important consequences for population and community dynamics. In particular, if intraspecific competition occurs over longer distances than interspecific competition (heteromyopia), coexistence can be promoted. We examined how intraspecific and interspecific competition scales with neighbor distance in a target-neighbor greenhouse competition experiment. Individuals from co-occurring forbs from calcareous grasslands were grown in isolation and with single conspecific or heterospecific neighbors at distances of 5, 10, or 15 cm (Plantago lanceolata vs. Plantago media and Hieracium pilosella vs. Prunella grandiflora). Neighbor effects were strong and declined with distance. Interaction distances varied greatly within and between species, but we found no evidence for heteromyopia. Instead, neighbor identity effects were mostly explained by relative size differences between target and neighbor. We found a complex interaction between final neighbor size and identity such that neighbor identity may become important only as the neighbor becomes very large compared with the target individual. Our results suggest that species-specific size differences between neighboring individuals determine both the strength of competitive interactions and the distance over which these interactions occur.

  12. Extremely long-distance seed dispersal by an overfished Amazonian frugivore.

    PubMed

    Anderson, Jill T; Nuttle, Tim; Saldaña Rojas, Joe S; Pendergast, Thomas H; Flecker, Alexander S

    2011-11-22

    Throughout Amazonia, overfishing has decimated populations of fruit-eating fishes, especially the large-bodied characid, Colossoma macropomum. During lengthy annual floods, frugivorous fishes enter vast Amazonian floodplains, consume massive quantities of fallen fruits and egest viable seeds. Many tree and liana species are clearly specialized for icthyochory, and seed dispersal by fish may be crucial for the maintenance of Amazonian wetland forests. Unlike frugivorous mammals and birds, little is known about seed dispersal effectiveness of fishes. Extensive mobility of frugivorous fish could result in extremely effective, multi-directional, long-distance seed dispersal. Over three annual flood seasons, we tracked fine-scale movement patterns and habitat use of wild Colossoma, and seed retention in the digestive tracts of captive individuals. Our mechanistic model predicts that Colossoma disperses seeds extremely long distances to favourable habitats. Modelled mean dispersal distances of 337-552 m and maximum of 5495 m are among the longest ever reported. At least 5 per cent of seeds are predicted to disperse 1700-2110 m, farther than dispersal by almost all other frugivores reported in the literature. Additionally, seed dispersal distances increased with fish size, but overfishing has biased Colossoma populations to smaller individuals. Thus, overexploitation probably disrupts an ancient coevolutionary relationship between Colossoma and Amazonian plants.

  13. Extremely long-distance seed dispersal by an overfished Amazonian frugivore

    PubMed Central

    Anderson, Jill T.; Nuttle, Tim; Saldaña Rojas, Joe S.; Pendergast, Thomas H.; Flecker, Alexander S.

    2011-01-01

    Throughout Amazonia, overfishing has decimated populations of fruit-eating fishes, especially the large-bodied characid, Colossoma macropomum. During lengthy annual floods, frugivorous fishes enter vast Amazonian floodplains, consume massive quantities of fallen fruits and egest viable seeds. Many tree and liana species are clearly specialized for icthyochory, and seed dispersal by fish may be crucial for the maintenance of Amazonian wetland forests. Unlike frugivorous mammals and birds, little is known about seed dispersal effectiveness of fishes. Extensive mobility of frugivorous fish could result in extremely effective, multi-directional, long-distance seed dispersal. Over three annual flood seasons, we tracked fine-scale movement patterns and habitat use of wild Colossoma, and seed retention in the digestive tracts of captive individuals. Our mechanistic model predicts that Colossoma disperses seeds extremely long distances to favourable habitats. Modelled mean dispersal distances of 337–552 m and maximum of 5495 m are among the longest ever reported. At least 5 per cent of seeds are predicted to disperse 1700–2110 m, farther than dispersal by almost all other frugivores reported in the literature. Additionally, seed dispersal distances increased with fish size, but overfishing has biased Colossoma populations to smaller individuals. Thus, overexploitation probably disrupts an ancient coevolutionary relationship between Colossoma and Amazonian plants. PMID:21429923

  14. West Nile virus (WNV) genome RNAs with up to three adjacent mutations that disrupt long distance 5'-3' cyclization sequence basepairs are viable

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Basu, Mausumi; Brinton, Margo A., E-mail: mbrinton@gsu.ed

    2011-03-30

    Mosquito-borne flavivirus genomes contain conserved 5' and 3' cyclization sequences (CYC) that facilitate long distance RNA-RNA interactions. In previous studies, flavivirus replicon RNA replication was completely inhibited by single or multiple mismatching CYC nt substitutions. In the present study, full-length WNV genomes with one, two or three mismatching CYC substitutions showed reduced replication efficiencies but were viable and generated revertants with increased replication efficiency. Several different three adjacent mismatching CYC substitution mutant RNAs were rescued by a second site mutation that created an additional basepair (nts 147-10913) on the internal genomic side of the 5'-3' CYC. The finding that full-lengthmore » genomes with up to three mismatching CYC mutations are viable and can be rescued by a single nt spontaneous mutation indicates that more than three adjacent CYC basepair substitutions would be required to increase the safety of vaccine genomes by creating mismatches in inter-genomic recombinants.« less

  15. Transactional Distance as a Predictor of Perceived Learner Satisfaction in Distance Learning Courses: A Case Study of Bachelor of Education Arts Program, University of Nairobi, Kenya

    ERIC Educational Resources Information Center

    Mbwesa, Joyce Kanini

    2014-01-01

    There is a long history of study and recognition of the critical role of interaction in supporting and even defining distance education. Interaction has been identified as key to the success of distance learning. It is key in fostering, supporting and engaging in the learning process. Moore (1989) posits that the physical distance that exists in…

  16. Soluto-inertial phenomena: Designing long-range, long-lasting, surface-specific interactions in suspensions

    PubMed Central

    Banerjee, Anirudha; Williams, Ian; Azevedo, Rodrigo Nery; Squires, Todd M.

    2016-01-01

    Equilibrium interactions between particles in aqueous suspensions are limited to distances less than 1 μm. Here, we describe a versatile concept to design and engineer nonequilibrium interactions whose magnitude and direction depends on the surface chemistry of the suspended particles, and whose range may extend over hundreds of microns and last thousands of seconds. The mechanism described here relies on diffusiophoresis, in which suspended particles migrate in response to gradients in solution. Three ingredients are involved: a soluto-inertial “beacon” designed to emit a steady flux of solute over long time scales; suspended particles that migrate in response to the solute flux; and the solute itself, which mediates the interaction. We demonstrate soluto-inertial interactions that extend for nearly half a millimeter and last for tens of minutes, and which are attractive or repulsive, depending on the surface chemistry of the suspended particles. Experiments agree quantitatively with scaling arguments and numerical computations, confirming the basic phenomenon, revealing design strategies, and suggesting a broad set of new possibilities for the manipulation and control of suspended particles. PMID:27410044

  17. Career Development as a Long-distance Hike

    PubMed Central

    2008-01-01

    Traditional images of achievement do not capture today’s more complex career development realities. Approaching career development as a long-distance expedition can help professionals in addressing the strenuous challenges they face, in seeing that a career can be built in many ways, and in taking a long-term view of their journeys. Skills are like muscles, self-efficacy is like sturdy boots, advancement “how-to’s” are like maps, and mentors are like trail guides. Among the tasks each hiker faces are selecting destinations, navigating through rough terrain and weather, and balancing their packs. To further their hikers’ resilience, departments should pay more attention to the career development ecology, including improving access to qualified trail guides and to alternate paths. PMID:18953615

  18. Distance Education at Memorial University of Newfoundland.

    ERIC Educational Resources Information Center

    Keough, Erin

    This presentation describes the distance education program at Memorial University (Newfoundland), which operates the Telemedicine Centre, including an audiographic, teleconference network that uses a combination of hardware and software to turn an MS DOS computer into an interactive long distance blackboard. Topics covered by the presentation…

  19. Why Do Long-Distance Travelers Have Improved Pancreatectomy Outcomes?

    PubMed

    Jindal, Manila; Zheng, Chaoyi; Quadri, Humair S; Ihemelandu, Chukwuemeka U; Hong, Young K; Smith, Andrew K; Dudeja, Vikas; Shara, Nawar M; Johnson, Lynt B; Al-Refaie, Waddah B

    2017-08-01

    Centralization of complex surgical care has led patients to travel longer distances. Emerging evidence suggested a negative association between increased travel distance and mortality after pancreatectomy. However, the reason for this association remains largely unknown. We sought to unravel the relationships among travel distance, receiving pancreatectomy at high-volume hospitals, delayed surgery, and operative outcomes. We identified 44,476 patients who underwent pancreatectomy for neoplasms between 2004 and 2013 at the reporting facility from the National Cancer Database. Multivariable analyses were performed to examine the independent relationships between increments in travel distance mortality (30-day and long-term survival) after adjusting for patient demographics, comorbidity, cancer stage, and time trend. We then examined how additional adjustment of procedure volume affected this relationship overall and among rural patients. Median travel distance to undergo pancreatectomy increased from 16.5 to 18.7 miles (p for trend < 0.001). Although longer travel distance was associated with delayed pancreatectomy, it was also related to higher odds of receiving pancreatectomy at a high-volume hospital and lower postoperative mortality. In multivariable analysis, difference in mortality among patients with varying travel distance was attenuated by adjustment for procedure volume. However, longest travel distance was still associated with a 77% lower 30-day mortality rate than shortest travel among rural patients, even when accounting for procedure volume. Our large national study found that the beneficial effect of longer travel distance on mortality after pancreatectomy is mainly attributable to increase in procedure volume. However, it can have additional benefits on rural patients that are not explained by volume. Distance can represent a surrogate for rural populations. Copyright © 2017 American College of Surgeons. Published by Elsevier Inc. All rights

  20. Long-distance thermal temporal ghost imaging over optical fibers

    NASA Astrophysics Data System (ADS)

    Yao, Xin; Zhang, Wei; Li, Hao; You, Lixing; Wang, Zhen; Huang, Yidong

    2018-02-01

    A thermal ghost imaging scheme between two distant parties is proposed and experimentally demonstrated over long-distance optical fibers. In the scheme, the weak thermal light is split into two paths. Photons in one path are spatially diffused according to their frequencies by a spatial dispersion component, then illuminate the object and record its spatial transmission information. Photons in the other path are temporally diffused by a temporal dispersion component. By the coincidence measurement between photons of two paths, the object can be imaged in a way of ghost imaging, based on the frequency correlation between photons in the two paths. In the experiment, the weak thermal light source is prepared by the spontaneous four-wave mixing in a silicon waveguide. The temporal dispersion is introduced by single mode fibers of 50 km, which also could be looked as a fiber link. Experimental results show that this scheme can be realized over long-distance optical fibers.

  1. Trait divergence and indirect interactions allow facilitation of congeneric species

    PubMed Central

    Beltrán, Elisa; Valiente-Banuet, Alfonso; Verdú, Miguel

    2012-01-01

    Background Plant facilitation occurs when the presence of a plant (i.e. a nurse plant) modifies the environment, making it more favourable for the establishment and survival of other species (i.e. facilitated plants), which can germinate and grow nearby. Facilitative associations can be maintained or turned into competition as the facilitated seedling grows. According to the competition-relatedness hypothesis that suggests that closely related species tend to compete more, facilitation turns into competition between phylogenetically close species. However, some examples of facilitation between congeneric species, which are supposed to be closely related species, have been found in nature. Scope In this work, some examples of congeneric facilitation and subsequent coexistence are reviewed and an attempt is made to explain those exceptions to the competition-relatedness hypothesis. Conclusions Two mechanisms are proposed that can switch the facilitation–competition balance: trait divergence and indirect interactions. When traits have diverged within the genus, the niche overlap is reduced and competition relaxed, thus allowing the coexistence of congeneric species. The presence of third interplayers (mycorrhizal fungi, seed dispersers, pollinators or pathogens) participating in the interaction between plants can alleviate the competition or enhance the reproduction and allow the coexistence of species that could not coexist in their absence. PMID:22543178

  2. Long-range interactions, wobbles, and phase defects in chains of model cilia

    NASA Astrophysics Data System (ADS)

    Brumley, Douglas R.; Bruot, Nicolas; Kotar, Jurij; Goldstein, Raymond E.; Cicuta, Pietro; Polin, Marco

    2016-12-01

    Eukaryotic cilia and flagella are chemo-mechanical oscillators capable of generating long-range coordinated motions known as metachronal waves. Pair synchronization is a fundamental requirement for these collective dynamics, but it is generally not sufficient for collective phase-locking, chiefly due to the effect of long-range interactions. Here we explore experimentally and numerically a minimal model for a ciliated surface: hydrodynamically coupled oscillators rotating above a no-slip plane. Increasing their distance from the wall profoundly affects the global dynamics, due to variations in hydrodynamic interaction range. The array undergoes a transition from a traveling wave to either a steady chevron pattern or one punctuated by periodic phase defects. Within the transition between these regimes the system displays behavior reminiscent of chimera states.

  3. Addition of long-distance heart procurement promotes changes in heart transplant waiting list status.

    PubMed

    Atik, Fernando Antibas; Couto, Carolina Fatima; Tirado, Freddy Ponce; Moraes, Camila Scatolin; Chaves, Renato Bueno; Vieira, Nubia W; Reis, João Gabbardo

    2014-01-01

    Evaluate the addition of long-distance heart procurement on a heart transplant program and the status of heart transplant recipients waiting list. Between September 2006 and October 2012, 72 patients were listed as heart transplant recipients. Heart transplant was performed in 41 (57%), death on the waiting list occurred in 26 (36%) and heart recovery occurred in 5 (7%). Initially, all transplants were performed with local donors. Long-distance, interstate heart procurement initiated in February 2011. Thirty (73%) transplants were performed with local donors and 11 (27%) with long-distance donors (mean distance=792 km±397). Patients submitted to interstate heart procurement had greater ischemic times (212 min ± 32 versus 90 min±18; P<0.0001). Primary graft dysfunction (distance 9.1% versus local 26.7%; P=0.23) and 1 month and 12 months actuarial survival (distance 90.1% and 90.1% versus local 90% and 86.2%; P=0.65 log rank) were similar among groups. There were marked incremental transplant center volume (64.4% versus 40.7%, P=0.05) with a tendency on less waiting list times (median 1.5 month versus 2.4 months, P=0.18). There was a tendency on reduced waiting list mortality (28.9% versus 48.2%, P=0.09). Incorporation of long-distance heart procurement, despite being associated with longer ischemic times, does not increase morbidity and mortality rates after heart transplant. It enhances viable donor pool, and it may reduce waiting list recipient mortality as well as waiting time.

  4. [Severe upper abdominal pain during a long distance flight].

    PubMed

    Bestehorn, D; Schmidt, C; Lock, G

    2014-10-01

    A 43-year-old woman of Ghanaian origin presented with severe upper abdominal pain starting on a long distance flight. Physical examination revealed tenderness on palpation in the left upper abdomen and flank. There was no report of pre-existing conditions or permanent medication in the medical history. Laboratory tests showed signs of haemolytic anemia and elevated inflammatory parameters. The "thick blood smear" was normal. Ultrasonography revealed an enlarged spleen (14×5 cm) with inhomogeneous parenchyma and vast, diffusely spread hypoechoic lesions in perihilar location, interpreted as extended splenic infarction. Symptom onset on a long distance flight, haemolytic anemia and extended splenic infarction led to the assumption of a vasoocclusive crisis with haemolysis. Moleculargenetic tests proved the presence of HbSC-sickle cell disease and heterozygous alpha-thalassemia. After infusion of crystalloid solution the patient was asymptomatic further on. Due to splenic infarction she received prophylactic treatment with Cefuroxim. A vaccination against pneumococci, meningococci and Haemophilus influenza B was recommended. Mild hypoxia and dehydration on a long distance flight can trigger a sickle cell crisis and may contribute to late clinical manifestation and diagnosis of sickle cell disease in some cases. Patients suffering from HbSC-sickle cell disease are at risk for the same life-threatening complications as patients with HbSS-sickle cell disease. HbSC-sickle cell disease should not be considered as a mild form of HbSS-sickle cell disease but as a separate disease with specific clinical manifestations. In contrast-enhanced ultrasonography, splenic infarction due to sickle cell crisis may markedly differ from "typical" arterial thromboembolic infarction. © Georg Thieme Verlag KG Stuttgart · New York.

  5. Long-range interactions between metastable rare gases atoms

    NASA Astrophysics Data System (ADS)

    Vrinceanu, D.; Marinescu, M.; Flannery, M. R.

    1998-10-01

    Knowledge of the long-range interaction between atoms and molecules is of fundamental importance for low-energy and low-temperature collisions. The electronic interaction between the charge distributions of two metastable rare gases atoms can be expanded in inverse powers of R, the internuclear distance. The coefficients C_6, C_8, and C_10 of, respectively, the R-6, R-8, and R-10 terms are calculated by integrating the products of the dynamic electric polarizabilities of the individual atoms at imaginary frequencies, which are in turn obtained by solving a system of coupled inhomogeneous differential equations. The triplet state spectrum of the rare gases atoms is described by precise l-dependent one-electron model potentials. Numerical results for the C_6, C_8, and C_10 dispersion coefficients for homonuclear and heteronuclear metastable rare gases diatoms are presented.

  6. Long-range interactions between metastable rare gases atoms

    NASA Astrophysics Data System (ADS)

    Vrinceanu, D.; Marinescu, M.; Flannery, M. R.

    1998-05-01

    Knowledge of the long-range interaction between atoms and molecules is of fundamental importance for low-energy and low-temperature collisions. The electronic interaction between the charge distributions of two metastable rare gases atoms can be expanded in inverse powers of R, the internuclear distance. The coefficients C_6, C_8, and C_10 of, respectively, the R-6, R-8, and R-10 terms are calculated by integrating the products of the dynamic electric polarizabilities of the individual atoms at imaginary frequencies, which are in turn obtained by solving a system of coupled inhomogeneous differential equations. The triplet state spectrum of the rare gases atoms is described by precise l-dependent one-electron model potentials. Numerical results for the C_6, C_8, and C_10 dispersion coefficients for homonuclear and heteronuclear metastable rare gases diatoms are presented.

  7. US long distance fiber optic networks: Technology, evolution and advanced concepts. Volume 2: Fiber optic technology and long distance networks

    NASA Astrophysics Data System (ADS)

    1986-10-01

    The study projects until 2000 the evolution of long distance fiber optic networks in the U.S. Volume 1 is the Executive Summary. Volume 2 focuses on fiber optic components and systems that are directly related to the operation of long-haul networks. Optimistic, pessimistic and most likely scenarios of technology development are presented. The activities of national and regional companies implementing fiber long haul networks are also highlighted, along with an analysis of the market and regulatory forces affecting network evolution. Volume 3 presents advanced fiber optic network concept definitions. Inter-LATA traffic is quantified and forms the basis for the construction of 11-, 15-, 17-, and 23-node networks. Using the technology projections from Volume 2, a financial model identifies cost drivers and determines circuit mile costs between any two LATAs. A comparison of fiber optics with alternative transmission concludes the report.

  8. US long distance fiber optic networks: Technology, evolution and advanced concepts. Volume 2: Fiber optic technology and long distance networks

    NASA Technical Reports Server (NTRS)

    1986-01-01

    The study projects until 2000 the evolution of long distance fiber optic networks in the U.S. Volume 1 is the Executive Summary. Volume 2 focuses on fiber optic components and systems that are directly related to the operation of long-haul networks. Optimistic, pessimistic and most likely scenarios of technology development are presented. The activities of national and regional companies implementing fiber long haul networks are also highlighted, along with an analysis of the market and regulatory forces affecting network evolution. Volume 3 presents advanced fiber optic network concept definitions. Inter-LATA traffic is quantified and forms the basis for the construction of 11-, 15-, 17-, and 23-node networks. Using the technology projections from Volume 2, a financial model identifies cost drivers and determines circuit mile costs between any two LATAs. A comparison of fiber optics with alternative transmission concludes the report.

  9. Psycho-Social Parameters in Young Female Long Distance Runners.

    ERIC Educational Resources Information Center

    Burke, Edmund J.; And Others

    This study was designed to determine selected psycho-social parameters associated with a group of teenage, female long distance runners. These young women, who train by running approximately 50-90 miles per week, had scores in certain physiological and anthropometric measurements which were among the most advantageous for running ever recorded in…

  10. Long-distance dispersal of Red-cockaded Woodpeckers in Texas

    Treesearch

    Richard N. Conner; D. Craig Rudolph; Richard R. Schaefer; Daniel Saenz

    1997-01-01

    The red-cockaded woodpecker (Picoides borealis) is a cooperatively breeding species indigenous to the mature pine forests of the Southeastern United States. Continued loss and fragmentation of the mature forests of the South have increased the isolation of extant woodpecker groups throughout the range of this endangered species. The authors discuss long-distance...

  11. Interaction and the Online Distance Classroom: Do Instructional Methods Effect the Quality of Interaction?

    ERIC Educational Resources Information Center

    Kanuka, Heather

    2011-01-01

    In this special issue, I bring together two studies to provide a comprehensive overview on diverse and interactive instructional methods aimed to facilitate higher levels of learning. One study explored the effects of group interaction using different instructional strategies focusing on the learning "process" using the Community of Inquiry…

  12. Long-distance travel modeling: proof of concept : research results digest.

    DOT National Transportation Integrated Search

    2016-04-01

    This research project was established to provide ADOT with direction on the best sources of data and best practices for updating its long-distance personal travel models to better reflect observed travel behavior. Its original intent was to recommend...

  13. Avian population consequences of climate change are most severe for long-distance migrants in seasonal habitats.

    PubMed

    Both, Christiaan; Van Turnhout, Chris A M; Bijlsma, Rob G; Siepel, Henk; Van Strien, Arco J; Foppen, Ruud P B

    2010-04-22

    One consequence of climate change is an increasing mismatch between timing of food requirements and food availability. Such a mismatch is primarily expected in avian long-distance migrants because of their complex annual cycle, and in habitats with a seasonal food peak. Here we show that insectivorous long-distance migrant species in The Netherlands declined strongly (1984-2004) in forests, a habitat characterized by a short spring food peak, but that they did not decline in less seasonal marshes. Also, within generalist long-distance migrant species, populations declined more strongly in forests than in marshes. Forest-inhabiting migrant species arriving latest in spring declined most sharply, probably because their mismatch with the peak in food supply is greatest. Residents and short-distance migrants had non-declining populations in both habitats, suggesting that habitat quality did not deteriorate. Habitat-related differences in trends were most probably caused by climate change because at a European scale, long-distance migrants in forests declined more severely in western Europe, where springs have become considerably warmer, when compared with northern Europe, where temperatures during spring arrival and breeding have increased less. Our results suggest that trophic mismatches may have become a major cause for population declines in long-distance migrants in highly seasonal habitats.

  14. Interactive distance learning for orthodontic residents: utilization and acceptability.

    PubMed

    Klein, Katherine P; Hannum, Wallace M; Koroluk, Lorne D; Proffit, William R

    2012-03-01

    Sharing resources through distance education has been proposed as 1 way to deal with a lack of full-time faculty in orthodontic residency programs. To keep distance education for orthodontic residents as cost-effective as possible while retaining interaction, we developed a "blended" interactive distance learning approach that combines observation of Web-based seminars with live postseminar discussions. For the 2009-2010 academic year, a grant from the American Association of Orthodontists opened access to the blended learning experience to all orthodontic programs in the United States and Canada. The specific aims of this project were to (1) measure programmatic interest in using blended distance learning, (2) determine resident and faculty interest, (3) determine the seminars' perceived usefulness, and (4) elicit feedback regarding future use. Participants in this project were expected to (1) read all assigned articles before viewing a recorded seminar, (2) watch a 1 to 1.5 hour recording of an actual interactive seminar on a Web site, and (3) participate in a 30-minute follow-up discussion immediately after watching the recorded seminar either with a faculty member at the participating institution or via a videoconference with the leader of the Web-based seminar. The residents and faculty then completed surveys about the experience. Half (52%) of the 63 orthodontic programs in the United States fully participated in this project. The blended approach to distance learning was judged to be effective and enjoyable; faculty members were somewhat more enthusiastic about the experience than were residents. Most residents were not adequately prepared for the seminars (only 14% read all preparatory articles in depth); this impacted their perception of the effectiveness and enjoyability of the experience (P = 0.0016). Prepared residents reported a greater ability to learn from the seminars (P = 0.0035) than those who did not read, and also indicated that they were more

  15. Virtual social interactions in social anxiety--the impact of sex, gaze, and interpersonal distance.

    PubMed

    Wieser, Matthias J; Pauli, Paul; Grosseibl, Miriam; Molzow, Ina; Mühlberger, Andreas

    2010-10-01

    In social interactions, interpersonal distance between interaction partners plays an important role in determining the status of the relationship. Interpersonal distance is an important nonverbal behavior, and is used to regulate personal space in a complex interplay with other nonverbal behaviors such as eye gaze. In social anxiety, studies regarding the impact of interpersonal distance on within-situation avoidance behavior are so far rare. Thus the present study aimed to scrutinize the relationship between gaze direction, sex, interpersonal distance, and social anxiety in social interactions. Social interactions were modeled in a virtual-reality (VR) environment, where 20 low and 19 high socially anxious women were confronted with approaching male and female characters, who stopped in front of the participant, either some distance away or close to them, and displayed either a direct or an averted gaze. Gaze and head movements, as well as heart rate, were measured as indices of avoidance behavior and fear reactions. High socially anxious participants showed a complex pattern of avoidance behavior: when the avatar was standing farther away, high socially anxious women avoided gaze contact with male avatars showing a direct gaze. Furthermore, they showed avoidance behavior (backward head movements) in response to male avatars showing a direct gaze, regardless of the interpersonal distance. Overall, the current study proved that VR social interactions might be a very useful tool for investigating avoidance behavior of socially anxious individuals in highly controlled situations. This might also be the first step in using VR social interactions in clinical protocols for the therapy of social anxiety disorder.

  16. An Assessment of Diarrhea Among Long-Distance Backpackers in the Sierra Nevada.

    PubMed

    Meyer, Derek J; Costantino, Amber; Spano, Susanne

    2017-03-01

    Diarrhea is a common problem among long-distance backpackers, ranging in overall incidence from 11-56% as reported by previous studies on the Appalachian Trail and Long Trail. Differences in age, sex, and regularity of standard backcountry hygiene recommendations and practices have been shown to significantly affect the incidence of diarrhea. No study to date has investigated these trends among long-distance backpackers on the John Muir Trail (JMT) in the Sierra Nevada mountain range of California. Retrospective analysis of online survey data gathered from long-distance backpackers who attempted a JMT trek in 2014. Data were assessed for the significance of variables that might contribute to the incidence and severity of on-trail diarrhea. Of 737 valid responders, 16.4% reported experiencing diarrhea (82% with minimal/mild severity; 18% with significant severity). Regular hand sanitizer use was significantly correlated with more severe diarrhea (P < .05), but had no effect on incidence. Regular hand sanitizer users followed all other recommended hygiene practices as frequently as or better than those not using hand sanitizer regularly. Of all backpackers, 88% filtered or treated their drinking water regularly, with 18% of those reporting diarrhea of any severity. JMT backpackers have a comparatively lower incidence of diarrhea than backpackers on other major long-distance backpacking routes in the United States. Most JMT backpackers follow standard backcountry hygiene recommendations, including regular filtration or treatment of drinking water. No statistical significance was found between the incidence of diarrhea and compliance with standard hygiene recommendations. Regular hand sanitizer use was significantly correlated with more severe diarrhea but was not associated with incidence. There was no significant difference in compliance with standard backcountry hygiene practices between regular and infrequent hand sanitizer users. Copyright © 2017 Wilderness

  17. Long Distance Dispersal Potential of Two Seagrasses Thalassia hemprichii and Halophila ovalis

    PubMed Central

    Wu, Kuoyan; Chen, Ching-Nen Nathan; Soong, Keryea

    2016-01-01

    The wide distribution of many seagrasses may be attributable to exploitation of currents. However, many species have seeds heavier than seawater, limiting surface floating, and thus, deep water becomes a potential barrier between suitable habitats. In this investigation, we studied the dispersal potential of various life history stages of two species of seagrasses, Thalassia hemprichii and Halophila ovalis, at Dongsha Atoll and Penghu Islands in Taiwan Strait, west Pacific. The adult plants of both species, often dislodged naturally from substrate by waves, could float, but only that of T. hemprichii could float for months and still remain alive and potentially able to colonize new territories. The seedlings of T. hemprichii could also float for about a month once failing to anchor to substrate of coral sand, but that of H. ovalis could not. The fruits and seeds of T. hemprichii could both float, but for too short a duration to enable long distance travel; those seeds released from long floating fruits had low germination rates in our tests. Obviously, their seeds are not adaptive for long distance dispersal. Fruits and seeds of H. ovalis do not float. The potential of animals as vectors was tested by feeding fruits and seeds of both species to a goose, a duck, and two fish in the laboratory. The fruits and seeds of T. hemprichii were digested and could no longer germinate; those of H. ovalis could pass through the digestive tracts and have a much higher germination rates than uningested controls. Therefore, birds could be important vectors for long distance dispersal of H. ovalis. The two seagrasses adopted very different dispersal mechanisms for long distance travel, and both exploited traits originally adaptive for other purposes. PMID:27248695

  18. Long Distance Dispersal Potential of Two Seagrasses Thalassia hemprichii and Halophila ovalis.

    PubMed

    Wu, Kuoyan; Chen, Ching-Nen Nathan; Soong, Keryea

    2016-01-01

    The wide distribution of many seagrasses may be attributable to exploitation of currents. However, many species have seeds heavier than seawater, limiting surface floating, and thus, deep water becomes a potential barrier between suitable habitats. In this investigation, we studied the dispersal potential of various life history stages of two species of seagrasses, Thalassia hemprichii and Halophila ovalis, at Dongsha Atoll and Penghu Islands in Taiwan Strait, west Pacific. The adult plants of both species, often dislodged naturally from substrate by waves, could float, but only that of T. hemprichii could float for months and still remain alive and potentially able to colonize new territories. The seedlings of T. hemprichii could also float for about a month once failing to anchor to substrate of coral sand, but that of H. ovalis could not. The fruits and seeds of T. hemprichii could both float, but for too short a duration to enable long distance travel; those seeds released from long floating fruits had low germination rates in our tests. Obviously, their seeds are not adaptive for long distance dispersal. Fruits and seeds of H. ovalis do not float. The potential of animals as vectors was tested by feeding fruits and seeds of both species to a goose, a duck, and two fish in the laboratory. The fruits and seeds of T. hemprichii were digested and could no longer germinate; those of H. ovalis could pass through the digestive tracts and have a much higher germination rates than uningested controls. Therefore, birds could be important vectors for long distance dispersal of H. ovalis. The two seagrasses adopted very different dispersal mechanisms for long distance travel, and both exploited traits originally adaptive for other purposes.

  19. Long-distance dispersal via ocean currents connects Omani clownfish populations throughout entire species range.

    PubMed

    Simpson, Stephen D; Harrison, Hugo B; Claereboudt, Michel R; Planes, Serge

    2014-01-01

    Dispersal is a crucial ecological process, driving population dynamics and defining the structure and persistence of populations. Measuring demographic connectivity between discreet populations remains a long-standing challenge for most marine organisms because it involves tracking the movement of pelagic larvae. Recent studies demonstrate local connectivity of reef fish populations via the dispersal of planktonic larvae, while biogeography indicates some larvae must disperse 100-1000 s kilometres. To date, empirical measures of long-distance dispersal are lacking and the full scale of dispersal is unknown. Here we provide the first measure of long-distance dispersal in a coral reef fish, the Omani clownfish Amphiprion omanensis, throughout its entire species range. Using genetic assignment tests we demonstrate bidirectional exchange of first generation migrants, with subsequent social and reproductive integration, between two populations separated by over 400 km. Immigration was 5.4% and 0.7% in each region, suggesting a biased southward exchange, and matched predictions from a physically-coupled dispersal model. This rare opportunity to measure long-distance dispersal demonstrates connectivity of isolated marine populations over distances of 100 s of kilometres and provides a unique insight into the processes of biogeography, speciation and adaptation.

  20. Long-Distance Dispersal via Ocean Currents Connects Omani Clownfish Populations throughout Entire Species Range

    PubMed Central

    Claereboudt, Michel R.; Planes, Serge

    2014-01-01

    Dispersal is a crucial ecological process, driving population dynamics and defining the structure and persistence of populations. Measuring demographic connectivity between discreet populations remains a long-standing challenge for most marine organisms because it involves tracking the movement of pelagic larvae. Recent studies demonstrate local connectivity of reef fish populations via the dispersal of planktonic larvae, while biogeography indicates some larvae must disperse 100–1000 s kilometres. To date, empirical measures of long-distance dispersal are lacking and the full scale of dispersal is unknown. Here we provide the first measure of long-distance dispersal in a coral reef fish, the Omani clownfish Amphiprion omanensis, throughout its entire species range. Using genetic assignment tests we demonstrate bidirectional exchange of first generation migrants, with subsequent social and reproductive integration, between two populations separated by over 400 km. Immigration was 5.4% and 0.7% in each region, suggesting a biased southward exchange, and matched predictions from a physically-coupled dispersal model. This rare opportunity to measure long-distance dispersal demonstrates connectivity of isolated marine populations over distances of 100 s of kilometres and provides a unique insight into the processes of biogeography, speciation and adaptation. PMID:25229550

  1. Measuring short distance dispersal of Alliaria petiolata and determining potential long distance dispersal mechanisms

    PubMed Central

    Anderson, Roger C.

    2018-01-01

    Introduction Alliaria petiolata, an herbaceous plant, has invaded woodlands in North America. Its ecology has been thoroughly studied, but an overlooked aspect of its biology is seed dispersal distances and mechanisms. We measured seed dispersal distances in the field and tested if epizoochory is a potential mechanism for long-distance seed dispersal. Methods Dispersal distances were measured by placing seed traps in a sector design around three seed point sources, which consisted of 15 second-year plants transplanted within a 0.25 m radius circle. Traps were placed at intervals ranging from 0.25–3.25 m from the point source. Traps remained in the field until a majority of seeds were dispersed. Eight probability density functions were fitted to seed trap counts via maximum likelihood. Epizoochory was tested as a potential seed dispersal mechanism for A. petiolata through a combination of field and laboratory experiments. To test if small mammals transport A. petiolata seeds in their fur, experimental blocks were placed around dense A. petiolata patches. Each block contained a mammal inclusion treatment (MIT) and control. The MIT consisted of a wood-frame (31 × 61× 31 cm) covered in wire mesh, except for the two 31 × 31 cm ends, placed over a germination tray filled with potting soil. A pan filled with bait was placed in the center of the tray. The control frame (11 × 31 × 61 cm) was placed over a germination tray and completely covered in wire mesh to exclude animal activity. Treatments were in the field for peak seed dispersal. In March, trays were moved to a greenhouse and A. petiolata seedlings were counted and then compared between treatments. To determine if A. petiolata seeds attach to raccoon (Procyon lotor) and white-tailed deer (Odocoileus virginianus) fur, wet and dry seeds were dropped onto wet and dry fur. Furs were rotated 180 degrees and the seeds that remained attached were counted. To measure seed retention, seeds were dropped on

  2. Long-distance dispersal of plants by vehicles as a driver of plant invasions.

    PubMed

    von der Lippe, Moritz; Kowarik, Ingo

    2007-08-01

    Roadsides are preferential migration corridors for invasive plant species and can act as starting points for plant invasions into adjacent habitats. Rapid spread and interrupted distribution patterns of introduced plant species indicate long-distance dispersal along roads. The extent to which this process is due to species' migration along linear habitats or, alternatively, to seed transport by vehicles has not yet been tested systematically. We tested this by sampling seeds inside long motorway tunnels to exclude nontraffic dispersal. Vehicles transported large amounts of seeds. The annual seed rain caused by vehicles on the roadsides of five different tunnel lanes within three tunnels along a single urban motorway in Berlin, Germany, ranged from 635 to 1579 seeds/m(2)/year. Seeds of non-native species accounted for 50.0% of the 204 species and 54.4% of the total 11,818 seeds trapped inside the tunnels. Among the samples were 39 (19.1%) highly invasive species that exhibit detrimental effects on native biodiversity in some parts of the world. By comparing the flora in the tunnel with that adjacent to the tunnel entrances we confirmed long-distance dispersal events (>250 m) for 32.3% of the sampled species. Seed sources in a radius of 100 m around the entrances of the tunnels had no significant effect on species richness and species composition of seed samples from inside the tunnels, indicating a strong effect of long-distance dispersal by vehicles. Consistently, the species composition of the tunnel seeds was more similar to the regional roadside flora of Berlin than to the local flora around the tunnel entrances. Long-distance dispersal occurred significantly more frequently in seeds of non-native (mean share 38.5%) than native species (mean share 4.1%). Our results showed that long-distance dispersal by vehicles was a routine rather than an occasional mechanism. Dispersal of plants by vehicles will thus accelerate plant invasions and induce rapid changes in

  3. Online Chemistry Modules: Interaction and Effective Faculty Facilitation

    ERIC Educational Resources Information Center

    Slocum, Laura E.; Towns Marcy Hamby; Zielinski, Theresa Julia

    2004-01-01

    Computer supported collaborative learning, cooperative learning combined with electronic communication, physical chemistry online modules, use of discussion boards, its advantages and limitations are experimented and discussed. The most important finding is the example of effective online faculty facilitation and interaction.

  4. Plantar Pressures During Long Distance Running: An Investigation of 10 Marathon Runners

    PubMed Central

    Hohmann, Erik; Reaburn, Peter; Tetsworth, Kevin; Imhoff, Andreas

    2016-01-01

    The objective of this study was to record plantar pressures using an in-shoe measuring system before, during, and after a marathon run in ten experienced long-distance runners with a mean age of 37.7 ± 11.5 years. Peak and mean plantar pressures were recorded before, after, and every three km during a marathon race. There were no significant changes over time in peak and mean plantar pressures for either the dominant or non-dominant foot. There were significant between foot peak and mean plantar pressure differences for the total foot (p = 0.0001), forefoot (p = 0.0001), midfoot (p = 0.02 resp. p = 0.006), hindfoot (p = 0.0001), first ray (p = 0.01 resp. p = 0.0001) and MTP (p = 0.05 resp. p = 0.0001). Long-distance runners do not demonstrate significant changes in mean or peak plantar foot pressures over the distance of a marathon race. However, athletes consistently favoured their dominant extremity, applying significantly higher plantar pressures through their dominant foot over the entire marathon distance. Key points Fatigue does not increase foot pressures Every runner has a dominant foot where pressures are higher and that he/she favours Foot pressures do not increase over the distance of a marathon run PMID:27274662

  5. The long distance transport of airborne Ambrosia pollen to the UK and the Netherlands from Central and south Europe

    NASA Astrophysics Data System (ADS)

    de Weger, Letty A.; Pashley, Catherine H.; Šikoparija, Branko; Skjøth, Carsten A.; Kasprzyk, Idalia; Grewling, Łukasz; Thibaudon, Michel; Magyar, Donat; Smith, Matt

    2016-12-01

    The invasive alien species Ambrosia artemisiifolia (common or short ragweed) is increasing its range in Europe. In the UK and the Netherlands, airborne concentrations of Ambrosia pollen are usually low. However, more than 30 Ambrosia pollen grains per cubic metre of air (above the level capable to trigger allergic symptoms) were recorded in Leicester (UK) and Leiden (NL) on 4 and 5 September 2014. The aims of this study were to determine whether the highly allergenic Ambrosia pollen recorded during the episode could be the result of long distance transport, to identify the potential sources of these pollen grains and to describe the conditions that facilitated this possible long distance transport. Airborne Ambrosia pollen data were collected at 10 sites in Europe. Back trajectory and atmospheric dispersion calculations were performed using HYSPLIT_4. Back trajectories calculated at Leicester and Leiden show that higher altitude air masses (1500 m) originated from source areas on the Pannonian Plain and Ukraine. During the episode, air masses veered to the west and passed over the Rhône Valley. Dispersion calculations showed that the atmospheric conditions were suitable for Ambrosia pollen released from the Pannonian Plain and the Rhône Valley to reach the higher levels and enter the airstream moving to northwest Europe where they were deposited at ground level and recorded by monitoring sites. The study indicates that the Ambrosia pollen grains recorded during the episode in Leicester and Leiden were probably not produced by local sources but transported long distances from potential source regions in east Europe, i.e. the Pannonian Plain and Ukraine, as well as the Rhône Valley in France.

  6. Long-distance practical quantum key distribution by entanglement swapping.

    PubMed

    Scherer, Artur; Sanders, Barry C; Tittel, Wolfgang

    2011-02-14

    We develop a model for practical, entanglement-based long-distance quantum key distribution employing entanglement swapping as a key building block. Relying only on existing off-the-shelf technology, we show how to optimize resources so as to maximize secret key distribution rates. The tools comprise lossy transmission links, such as telecom optical fibers or free space, parametric down-conversion sources of entangled photon pairs, and threshold detectors that are inefficient and have dark counts. Our analysis provides the optimal trade-off between detector efficiency and dark counts, which are usually competing, as well as the optimal source brightness that maximizes the secret key rate for specified distances (i.e. loss) between sender and receiver.

  7. Interaction in Distance Education Environments: A Trend Analysis

    ERIC Educational Resources Information Center

    Karatas, Serçin; Yilmaz, Ayse Bagriacik; Dikmen, Cemal Hakan; Ermis, Ugur Ferhat; Gürbüz, Onur

    2017-01-01

    The aim of this study is to determine the trend concerning interaction in distance education between the years 2011 and 2015. According to this aim, 544 articles in the databases of EBSCO, Scopus, and Web of Science were examined. The examination has been conducted on the basis of various variables including year, country, number of authors,…

  8. Mode-resolved frequency comb interferometry for high-accuracy long distance measurement

    PubMed Central

    van den Berg, Steven. A.; van Eldik, Sjoerd; Bhattacharya, Nandini

    2015-01-01

    Optical frequency combs have developed into powerful tools for distance metrology. In this paper we demonstrate absolute long distance measurement using a single femtosecond frequency comb laser as a multi-wavelength source. By applying a high-resolution spectrometer based on a virtually imaged phased array, the frequency comb modes are resolved spectrally to the level of an individual mode. Having the frequency comb stabilized against an atomic clock, thousands of accurately known wavelengths are available for interferometry. From the spectrally resolved output of a Michelson interferometer a distance is derived. The presented measurement method combines spectral interferometry, white light interferometry and multi-wavelength interferometry in a single scheme. Comparison with a fringe counting laser interferometer shows an agreement within <10−8 for a distance of 50 m. PMID:26419282

  9. Perspectives on Long-Distance Air Travel with Type 1 Diabetes.

    PubMed

    Pinsker, Jordan E; Schoenberg, Benjamen E; Garey, Colleen; Runion, Asher; Larez, Arianna; Kerr, David

    2017-12-01

    We sought to determine the real-life experiences of individuals traveling long distance (across five or more time-zones) with type 1 diabetes (T1D). Five hundred three members of the T1D Exchange online community ( www.myglu.org ) completed a 45-question survey about their travel experiences flying long distance. The cohort was stratified by duration of T1D and whether or not participants used continuous subcutaneous insulin infusion (CSII) therapy and/or a continuous glucose monitor (CGM). In the last 5 years, 71% of participants had flown long distance. When asked about their perceived "fear of flying," CSII users (with and without a CGM) reported their primary anxiety was "losing supplies," while non-CSII users described concerns over "unstable blood glucose (highs and lows)" (P < 0.05). In addition, 74% of participants reported more hypoglycemia and/or hyperglycemia while traveling overseas and 9% had avoided international travel altogether because of problems related to diabetes management. Furthermore, 22% of participants had run out of insulin at some point during a trip and 37% reported inadequate attention in current sources of information to the unpredictability of self-management needs while traveling. Especially problematic for individuals traveling with T1D are a lack of resources adequately addressing (1) protocols for emergencies while abroad, (2) how to navigate airport security, and (3) managing basal insulin rates when crossing time zones. A strong need exists for easily accessible, free resources for traveling with T1D that is tailored to both device use and duration of the disease.

  10. 2. Long distance view from the SW of former Cotton ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Long distance view from the SW of former Cotton Yards (now used as a parking lot); Cotton Yard Gates at far right, Red Building and Produce Freight Warehouse in background. - Central of Georgia Railway, Cotton Yard Gates, West Broad Street, Savannah, Chatham County, GA

  11. Metal species involved in long distance metal transport in plants

    PubMed Central

    Álvarez-Fernández, Ana; Díaz-Benito, Pablo; Abadía, Anunciación; López-Millán, Ana-Flor; Abadía, Javier

    2014-01-01

    The mechanisms plants use to transport metals from roots to shoots are not completely understood. It has long been proposed that organic molecules participate in metal translocation within the plant. However, until recently the identity of the complexes involved in the long-distance transport of metals could only be inferred by using indirect methods, such as analyzing separately the concentrations of metals and putative ligands and then using in silico chemical speciation software to predict metal species. Molecular biology approaches also have provided a breadth of information about putative metal ligands and metal complexes occurring in plant fluids. The new advances in analytical techniques based on mass spectrometry and the increased use of synchrotron X-ray spectroscopy have allowed for the identification of some metal-ligand species in plant fluids such as the xylem and phloem saps. Also, some proteins present in plant fluids can bind metals and a few studies have explored this possibility. This study reviews the analytical challenges researchers have to face to understand long-distance metal transport in plants as well as the recent advances in the identification of the ligand and metal-ligand complexes in plant fluids. PMID:24723928

  12. Long-distance running, bone density, and osteoarthritis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lane, N.E.; Bloch, D.A.; Jones, H.H.

    Forty-one long-distance runners aged 50 to 72 years were compared with 41 matched community controls to examine associations of repetitive, long-term physical impact (running) with osteoarthritis and osteoporosis. Roentgenograms of hands, lateral lumbar spine, and knees were assessed without knowledge of running status. A computed tomographic scan of the first lumbar vertebra was performed to quantitate bone mineral content. Runners, both male and female, have approximately 40% more bone mineral than matched controls. Female runners, but not male runners, appear to have somewhat more sclerosis and spur formation in spine and weight-bearing knee x-ray films, but not in hand x-raymore » films. There were no differences between groups in joint space narrowing, crepitation, joint stability, or symptomatic osteoarthritis. Running is associated with increased bone mineral but not, in this cross-sectional study, with clinical osteoarthritis.« less

  13. Recorded interactive seminars and follow-up discussions as an effective method for distance learning.

    PubMed

    Miller, Kenneth T; Hannum, Wallace M; Proffit, William R

    2011-03-01

    Previous studies have suggested that, although orthodontic residents prefer to be live and interactive in a seminar, they learn almost as much when watching a previously recorded interactive seminar and following up with live discussion. Our objective was to test the effectiveness and acceptability of using previously recorded interactive seminars and different types of live follow-up discussions. Residents at schools participating from a distance completed preseminar readings and at their convenience watched streaming video of some or all recordings of 4 interactive seminar sequences consisting of 6 seminars each. Afterward, distant residents participated in 1 of 4 types of interaction: local follow-up discussion, videoconference, teleconference, and no discussion. The effectiveness of the seminar sequences was tested by pretest and posttest scores. Acceptability was evaluated from ratings of aspects of the seminar and discussion experience. Open-ended questions allowed residents to express what they liked and to suggest changes in their experiences. In each seminar sequence, test scores of schools participating through recordings and follow-up discussions improved more than those participating live and interactive. After viewing, residents preferred local follow-up discussion, which was not statistically different from participating live and interactive both locally and from a distance. Videoconference and teleconference discussions were both more acceptable to residents than no follow-up discussion, which was found to be significantly below all methods tested. When residents are live and interactive in a seminar, there does not appear to be a significant difference between being local vs at a distance. Recorded interactive seminars with follow-up discussions are also an effective and acceptable method of distance learning. Residents preferred local follow-up discussion, but, at a distance, they preferred videoconference to both teleconference and no discussion

  14. Facilitative and competitive interaction components among New England salt marsh plants

    USDA-ARS?s Scientific Manuscript database

    Intra- and interspecific interactions can be broken down into facilitative and competitive components. The net interaction between two organisms is simply the sum of these counteracting elements. Disentangling the positive and negative components of species interactions is a critical step in advanc...

  15. Phenological differences among selected residents and long-distance migrant bird species in central Europe

    NASA Astrophysics Data System (ADS)

    Bartošová, Lenka; Trnka, Miroslav; Bauer, Zdeněk; Možný, Martin; Štěpánek, Petr; Žalud, Zdeněk

    2014-07-01

    The phenological responses to climate of residents and migrants (short- and long-distance) differ. Although few previous studies have focussed on this topic, the agree that changes in phenology are more apparent for residents than for long-distance migrants. We analysed the breeding times of two selected residents ( Sitta europaea, Parus major) and one long-distance migrant ( Ficedula albicollis) from 1961 to 2007 in central Europe. The timing of the phenophases of all three bird species showed a significant advance to earlier times. Nevertheless, the most marked shift was observed for the long-distance migrant (1.9 days per decade on average in mean laying date with linearity at the 99.9 % confidence level). In contrast, the shifts shown by the residents were smaller (1.6 days for S. europaea and 1.5 days for P. major also on average in mean laying date for both, with linearity at the 95 % confidence level). Spearman rank correlation coefficients calculated for pairs of phenophases of given bird species in 20-year subsamples (e.g. 1961-1980, 1962-1981) showed higher phenological separation between the residents and the migrant. This separation is most apparent after the 1980s. Thus, our results indicate that the interconnections between the studied phenological stages of the three bird species are becoming weaker.

  16. The Effects of Long Distance Running on Preadolescent Children.

    ERIC Educational Resources Information Center

    Covington, N. Kay

    This study investigated the effects of selected physiological variables on preadolescent male and female long distance runners. The trained group was comprised of 20 children between the ages of 8 and 10 who had been running a minimum of 20 miles per week for two months or longer. The control group was made up of 20 children of the same ages who…

  17. Predictors of Satisfaction in Geographically Close and Long-Distance Relationships

    ERIC Educational Resources Information Center

    Lee, Ji-yeon; Pistole, M. Carole

    2012-01-01

    In this study, the authors examined geographically close (GCRs) and long-distance (LDRs) romantic relationship satisfaction as explained by insecure attachment, self-disclosure, gossip, and idealization. After college student participants (N = 536) completed a Web survey, structural equation modeling (SEM) multigroup analysis revealed that the GCR…

  18. The monarch butterfly genome yields insights into long-distance migration

    PubMed Central

    Zhan, Shuai; Merlin, Christine; Boore, Jeffrey L.; Reppert, Steven M.

    2011-01-01

    SUMMARY We present the draft 273 Mb genome of the migratory monarch butterfly (Danaus plexippus) and a set of 16, 866 protein-coding genes. Orthology properties suggest that the Lepidoptera are the fastest evolving insect order yet examined. Compared to the silkmoth Bombyx mori, the monarch genome shares prominent similarity in orthology content, microsynteny, and protein family sizes. The monarch genome reveals: a vertebrate-like opsin whose existence in insects is widespread; a full repertoire of molecular components for the monarch circadian clockwork; all members of the juvenile hormone biosynthetic pathway whose regulation shows unexpected sexual dimorphism; additional molecular signatures of oriented flight behavior; microRNAs that are differentially expressed between summer and migratory butterflies; monarch-specific expansions of chemoreceptors potentially important for long-distance migration; and a variant of the sodium/potassium pump that underlies a valuable chemical defense mechanism. The monarch genome enhances our ability to better understand the genetic and molecular basis of long-distance migration. PMID:22118469

  19. Long distance education for croatian nurses with open source software.

    PubMed

    Radenovic, Aleksandar; Kalauz, Sonja

    2006-01-01

    Croatian Nursing Informatics Association (CNIA) has been established as result of continuing work on promoting nursing informatics in Croatia. Main goals of CNIA are promoting nursing informatics and education of nurses about nursing informatics and using information technology in nursing process. CNIA in start of work is developed three courses from nursing informatics all designed with support of long distance education with open source software. Courses are: A - 'From Data to Wisdom', B - 'Introduction to Nursing Informatics' and C - 'Nursing Informatics I'. Courses A and B are obligatory for C course. Technology used to implement these online courses is based on the open source Learning Management System (LMS), Claroline, free online collaborative learning platform. Courses are divided in two modules/days. First module/day participants have classical approach to education and second day with E-learning from home. These courses represent first courses from nursing informatics' and first long distance education for nurses also.

  20. Disruption of long-distance highly conserved noncoding elements in neurocristopathies.

    PubMed

    Amiel, Jeanne; Benko, Sabina; Gordon, Christopher T; Lyonnet, Stanislas

    2010-12-01

    One of the key discoveries of vertebrate genome sequencing projects has been the identification of highly conserved noncoding elements (CNEs). Some characteristics of CNEs include their high frequency in mammalian genomes, their potential regulatory role in gene expression, and their enrichment in gene deserts nearby master developmental genes. The abnormal development of neural crest cells (NCCs) leads to a broad spectrum of congenital malformation(s), termed neurocristopathies, and/or tumor predisposition. Here we review recent findings that disruptions of CNEs, within or at long distance from the coding sequences of key genes involved in NCC development, result in neurocristopathies via the alteration of tissue- or stage-specific long-distance regulation of gene expression. While most studies on human genetic disorders have focused on protein-coding sequences, these examples suggest that investigation of genomic alterations of CNEs will provide a broader understanding of the molecular etiology of both rare and common human congenital malformations. © 2010 New York Academy of Sciences.

  1. Study on the Implementation of Interaction Teaching Mode in Distance Education

    ERIC Educational Resources Information Center

    Zhou, Chunyu; Xu, Zhenhui

    2015-01-01

    By analyzing the learning characteristics of learners and the features of interactive teaching in distance education, this paper proposes the curriculum implementation subject of network education, namely objects multi-directional interaction teaching mode, so as to improve teaching effectiveness and achieve teaching objectives to ensure the…

  2. Design and Operation of the World's First Long Distance Bauxite Slurry Pipeline

    NASA Astrophysics Data System (ADS)

    Gandhi, Ramesh; Weston, Mike; Talavera, Maru; Brittes, Geraldo Pereira; Barbosa, Eder

    Mineracão Bauxita Paragominas (MBP) is the first long distance slurry pipeline transporting bauxite slurry. Bauxite had developed a reputation for being difficult to hydraulically transport using long distance pipelines. This myth has now been proven wrong. The 245-km- long, 13.5 MTPY capacity MBP pipeline was designed and commissioned by PSI for CVRD. The pipeline is located in the State of Para, Brazil. The Miltonia bauxite mine is in a remote location with no other efficient means of transport. The bauxite slurry is delivered to Alunorte Alumina refinery located near Barcarena. This first of its kind pipeline required significant development work in order to assure technical and economic feasibility. This paper describes the technical aspects of design of the pipeline. It also summarizes the operating experience gained during the first year of operation.

  3. Living Gerontology: Providing Long-Distance, Long-term Care.

    PubMed

    Kivnick, Helen Q

    2017-02-01

    My own living and working through normative family transitions of parent care (as both a professional gerontologist and an intergenerational family member) facilitated five important kinds of growth: (a) providing parent care with optimal integrity; (b) understanding, elaborating, and teaching life-cycle theory with increasing depth; (c) using this theory to enrich practice approaches to long-term care; (d) identifying valuable new research directions; and (e) creating a multidimensional professional life that furthers theoretical development and identifies practice principles that promote individual, familial, and societal experiences of a "good old age." This reflective essay addresses these different kinds of growth, as they emerged from and contribute to the ever-developing gerontological domains of theory and practice. © The Author 2016. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  4. Long-distance interaction of the integrated HPV fragment with MYC gene and 8q24.22 region upregulating the allele-specific MYC expression in HeLa cells.

    PubMed

    Shen, Congle; Liu, Yongzhen; Shi, Shu; Zhang, Ruiyang; Zhang, Ting; Xu, Qiang; Zhu, Pengfei; Chen, Xiangmei; Lu, Fengmin

    2017-08-01

    Human papillomavirus (HPV) infection is the most important risk factor for cervical cancer development. In HeLa cell line, the HPV viral genome is integrated at 8q24 in one allele of chromosome 8. It has been reported that the HPV fragment integrated in HeLa genome can cis-activate the expression of proto-oncogene MYC, which is located at 500 kb downstream of the integrated site. However, the underlying molecular mechanism of this regulation is unknown. A recent study reported that MYC was highly expressed exclusively from the HPV-integrated haplotype, and a long-range chromatin interaction between the integrated HPV fragment and MYC gene has been hypothesized. In this study, we provided the experimental evidences supporting this long-range chromatin interaction in HeLa cells by using Chromosome Conformation Capture (3C) method. We found that the integrated HPV fragment, MYC and 8q24.22 was close to each other and might form a trimer in spatial location. When knocking out the integrated HPV fragment or 8q24.22 region from chromosome 8 by CRISPR/Cas9 system, the expression of MYC reduced dramatically in HeLa cells. Interestingly, decreased expression was only observed in three from eight cell clones, when only one 8q24.22 allele was knocked out. Functionally, HPV knockout caused senescence-associated acidic β-gal activity in HeLa cells. These data indicate a long-distance interaction of the integrated HPV fragment with MYC gene and 8q24.22 region, providing an alternative mechanism relevant to the carcinogenicity of HPV integration. © 2017 The Authors International Journal of Cancer published by John Wiley & Sons Ltd on behalf of UICC.

  5. Long-term follow-up of psilocybin-facilitated smoking cessation.

    PubMed

    Johnson, Matthew W; Garcia-Romeu, Albert; Griffiths, Roland R

    2017-01-01

    A recent open-label pilot study (N = 15) found that two to three moderate to high doses (20 and 30 mg/70 kg) of the serotonin 2A receptor agonist, psilocybin, in combination with cognitive behavioral therapy (CBT) for smoking cessation, resulted in substantially higher 6-month smoking abstinence rates than are typically observed with other medications or CBT alone. To assess long-term effects of a psilocybin-facilitated smoking cessation program at ≥12 months after psilocybin administration. The present report describes biologically verified smoking abstinence outcomes of the previous pilot study at ≥12 months, and related data on subjective effects of psilocybin. All 15 participants completed a 12-month follow-up, and 12 (80%) returned for a long-term (≥16 months) follow-up, with a mean interval of 30 months (range = 16-57 months) between target-quit date (i.e., first psilocybin session) and long-term follow-up. At 12-month follow-up, 10 participants (67%) were confirmed as smoking abstinent. At long-term follow-up, nine participants (60%) were confirmed as smoking abstinent. At 12-month follow-up 13 participants (86.7%) rated their psilocybin experiences among the five most personally meaningful and spiritually significant experiences of their lives. These results suggest that in the context of a structured treatment program, psilocybin holds considerable promise in promoting long-term smoking abstinence. The present study adds to recent and historical evidence suggesting high success rates when using classic psychedelics in the treatment of addiction. Further research investigating psilocybin-facilitated treatment of substance use disorders is warranted.

  6. The earliest long-distance obsidian transport: Evidence from the ∼200 ka Middle Stone Age Sibilo School Road Site, Baringo, Kenya.

    PubMed

    Blegen, Nick

    2017-02-01

    This study presents the earliest evidence of long-distance obsidian transport at the ∼200 ka Sibilo School Road Site (SSRS), an early Middle Stone Age site in the Kapthurin Formation, Kenya. The later Middle Pleistocene of East Africa (130-400 ka) spans significant and interrelated behavioral and biological changes in human evolution including the first appearance of Homo sapiens. Despite the importance of the later Middle Pleistocene, there are relatively few archaeological sites in well-dated contexts (n < 10) that document hominin behavior from this time period. In particular, geochemically informed evidence of long-distance obsidian transport, important for investigating expansion of intergroup interactions in hominin evolution, is rare from the Middle Pleistocene record of Africa. The SSRS offers a unique contribution to this small but growing dataset. Tephrostratigraphic analysis of tuffs encasing the SSRS provides a minimum age of ∼200 ka for the site. Levallois points and methods of core preparation demonstrate characteristic Middle Stone Age lithic technologies present at the SSRS. A significant portion (43%) of the lithic assemblage is obsidian. The SSRS obsidian comes from three different sources located at distances of 25 km, 140 km and 166 km from the site. The majority of obsidian derives from the farthest source, 166 km to the south of the site. The SSRS thus provides important new evidence that long-distance raw material transport, and the expansion of hominin intergroup interactions that this entails, was a significant feature of hominin behavior ∼200 ka, the time of the first appearance of H. sapiens, and ∼150,000 years before similar behaviors were previously documented in the region. Copyright © 2016 Elsevier Ltd. All rights reserved.

  7. Exploring the Use of MXit: A Cell-Phone Social Network to Facilitate Learning in Distance Education

    ERIC Educational Resources Information Center

    Makoe, Mpine

    2010-01-01

    The aim of this paper is to investigate the pedagogical suitability of using cell phones to enhance learning through social interaction in distance education. Social interaction was used as a conceptual framework to explore the potential for using "MXit"--a cell-phone instant messaging system--to support and enhance learning for distance…

  8. The ESCRT regulator Did2 maintains the balance between long-distance endosomal transport and endocytic trafficking

    PubMed Central

    Haag, Carl

    2017-01-01

    In highly polarised cells, like fungal hyphae, early endosomes function in both endocytosis as well as long-distance transport of various cargo including mRNA and protein complexes. However, knowledge on the crosstalk between these seemingly different trafficking processes is scarce. Here, we demonstrate that the ESCRT regulator Did2 coordinates endosomal transport in fungal hyphae of Ustilago maydis. Loss of Did2 results in defective vacuolar targeting, less processive long-distance transport and abnormal shuttling of early endosomes. Importantly, the late endosomal protein Rab7 and vacuolar protease Prc1 exhibit increased shuttling on these aberrant endosomes suggesting defects in endosomal maturation and identity. Consistently, molecular motors fail to attach efficiently explaining the disturbed processive movement. Furthermore, the endosomal mRNP linker protein Upa1 is hardly present on endosomes resulting in defects in long-distance mRNA transport. In conclusion, the ESCRT regulator Did2 coordinates precise maturation of endosomes and thus provides the correct membrane identity for efficient endosomal long-distance transport. PMID:28422978

  9. [Onyx embolization for treatment of dural arteriovenous fistula: comparison of long- distance versus routine injection method].

    PubMed

    He, Xiao-Yan; Zhang, Guo-Zhong; Li, Ming-Zhou; Wang, Gang; Liu, Dan; Qi, Song-Tao; Li, Wei-Guang; Feng, Wen-Feng

    2016-03-01

    To compare the efficacy, clinical characteristics, safety, injection time and radiation exposure of Onyx embolization using a long-distance injection method and routine injection method for management of dural arteriovenous fistula (DAVF). The clinical data were retrospectively analyzed in 59 patients with DAVF treated with Onyx embolization using long-distance injection method (28 patients) and routine injection method (31 patients). The efficacy, safety, injection time and radiation exposure during Onyx embolization were compared between the two injections methods. The average radiation dose exposure to the surgeon per procedure was significantly lower in the long-distance injection group than in the routine group. The injection time (P=0.53), injection volume (P=0.78), number of supply arteries (P=0.80), Cognard types (P=0.67), and effect of embolization (P=0.88) were all similar between the two groups. Endovaseular treatment of intracranial DAVF with Onyx embolization using the long-distance injection method is feasible, safe and effective and can reduce the radiation exposure to the surgeon.

  10. Engaging Graduate-Level Distance Learners in Research: A Collaborative Investigation of Rural Aging.

    PubMed

    O'Connor, Melissa L; Fuller-Iglesias, Heather; Bishop, Alexander J; Doll, Gayle; Killian, Timothy; Margrett, Jennifer; Pearson-Scott, Jean

    2016-01-01

    Online educational programs pose challenges to nonresidential graduate students for whom research is a key professional development experience. In this article, the authors share their pedagogical approach to engaging graduate-level online distance learners in research. Five students enrolled in an online master's degree program participated in a directed research course designed to facilitate a semester-long, collaborative, hands-on research experience in gerontology. As such, students recruited participants and conducted phone interviews for a multisite study examining aging in place in rural areas. Several strategies were used to facilitate student engagement and learning, including: regular meetings with faculty mentors, creation of a research team across institutions, interactive training, and technological tools to aid in communication. The authors discuss the process of implementing the project, challenges that arose, strategies for dealing with these issues, and a pedagogical framework that could be used to guide future endeavors of this type.

  11. Interactive ESL In-Service Teacher Training via Distance Education.

    ERIC Educational Resources Information Center

    Power, Michael A.

    The Hawaii State Department of Education offers university credit courses in English-as-a-Second-Language (ESL) techniques to all public school teachers, but the scarcity of trainers and the distance between schools and training sites constitute substantial obstacles. With the cooperation of the University of Hawaii's interactive television…

  12. Taking the Flight to the Enemy: Chinese Thinking About Long-Distance and Expeditionary Operations

    DTIC Science & Technology

    2016-07-01

    www.StrategicStudiesInstitute.army.mil/newsletter. ISBN 1-58487-729-4 vii FOREWORD The Chinese People’s Liberation Army ( PLA ) was once focused on China’s immediate...periphery. The PLA Navy had no “blue water” naval capabilities and very limited combat logistics support. The Air Force could not fly long-distance...provides internal critiques of PLA capabilities. He starts with an analysis of the book Long-Distance Operations, by a strategist from the Academy of

  13. Testing the Münch hypothesis of long distance phloem transport in plants.

    PubMed

    Knoblauch, Michael; Knoblauch, Jan; Mullendore, Daniel L; Savage, Jessica A; Babst, Benjamin A; Beecher, Sierra D; Dodgen, Adam C; Jensen, Kaare H; Holbrook, N Michele

    2016-06-02

    Long distance transport in plants occurs in sieve tubes of the phloem. The pressure flow hypothesis introduced by Ernst Münch in 1930 describes a mechanism of osmotically generated pressure differentials that are supposed to drive the movement of sugars and other solutes in the phloem, but this hypothesis has long faced major challenges. The key issue is whether the conductance of sieve tubes, including sieve plate pores, is sufficient to allow pressure flow. We show that with increasing distance between source and sink, sieve tube conductivity and turgor increases dramatically in Ipomoea nil. Our results provide strong support for the Münch hypothesis, while providing new tools for the investigation of one of the least understood plant tissues.

  14. [Health risks of long-distance air travel. Role of the general practitioner].

    PubMed

    Bazex, Jacques; Cabanis, Emmanuel Alain

    2010-06-01

    Air transport is seeing an increase in long-distance flights (12-16 hours average flight time), greater seating capacity, and a higher proportion of elderly, and hence more fragile, passengers. The French Academy of Medicine recommends that medical care be reinforced, particularly on long-distance flights, through the following measures: (i) passengers should be informed in advance of potential risks, through a Passenger's Guide, (ii) all future passengers should be encouraged to seek health advice and information from their general practitioner, (iii) flight crew members should receive training as "in-flight medical correspondents", and (iv) airlines and plane designers should reserve a "medical space" on the plane, equipped with appropriate medical materials.

  15. Long-Distance and Frequent Movements of the Flying-Fox Pteropus poliocephalus: Implications for Management

    PubMed Central

    Roberts, Billie J.; Catterall, Carla P.; Eby, Peggy; Kanowski, John

    2012-01-01

    Flying-foxes (Pteropodidae) are large bats capable of long-distance flight. Many species are threatened; some are considered pests. Effective conservation and management of flying-foxes are constrained by lack of knowledge of their ecology, especially of movement patterns over large spatial scales. Using satellite telemetry, we quantified long-distance movements of the grey-headed flying-fox Pteropus poliocephalus among roost sites in eastern Australia. Fourteen adult males were tracked for 2–40 weeks (mean 25 weeks). Collectively, these individuals utilised 77 roost sites in an area spanning 1,075 km by 128 km. Movement patterns varied greatly between individuals, with some travelling long distances. Five individuals travelled cumulative distances >1,000 km over the study period. Five individuals showed net displacements >300 km during one month, including one movement of 500 km within 48 hours. Seasonal movements were consistent with facultative latitudinal migration in part of the population. Flying-foxes shifted roost sites frequently: 64% of roost visits lasted <5 consecutive days, although some individuals remained at one roost for several months. Modal 2-day distances between consecutive roosts were 21–50 km (mean 45 km, range 3–166 km). Of 13 individuals tracked for >12 weeks, 10 moved >100 km in one or more weeks. Median cumulative displacement distances over 1, 10 and 30 weeks were 0 km, 260 km and 821 km, respectively. On average, over increasing time-periods, one additional roost site was visited for each additional 100 km travelled. These findings explain why culling and relocation attempts have had limited success in resolving human-bat conflicts in Australia. Flying-foxes are highly mobile between camps and regularly travel long distances. Consequently, local control actions are likely to have only temporary effects on local flying-fox populations. Developing alternative methods to manage these conflicts remains an important challenge that

  16. Fiber optic cable-based high-resolution, long-distance VGA extenders

    NASA Astrophysics Data System (ADS)

    Rhee, Jin-Geun; Lee, Iksoo; Kim, Heejoon; Kim, Sungjoon; Koh, Yeon-Wan; Kim, Hoik; Lim, Jiseok; Kim, Chur; Kim, Jungwon

    2013-02-01

    Remote transfer of high-resolution video information finds more applications in detached display applications for large facilities such as theaters, sports complex, airports, and security facilities. Active optical cables (AOCs) provide a promising approach for enhancing both the transmittable resolution and distance that standard copper-based cables cannot reach. In addition to the standard digital formats such as HDMI, the high-resolution, long-distance transfer of VGA format signals is important for applications where high-resolution analog video ports should be also supported, such as military/defense applications and high-resolution video camera links. In this presentation we present the development of a compressionless, high-resolution (up to WUXGA, 1920x1200), long-distance (up to 2 km) VGA extenders based on serialized technique. We employed asynchronous serial transmission and clock regeneration techniques, which enables lower cost implementation of VGA extenders by removing the necessity for clock transmission and large memory at the receiver. Two 3.125-Gbps transceivers are used in parallel to meet the required maximum video data rate of 6.25 Gbps. As the data are transmitted asynchronously, 24-bit pixel clock time stamp is employed to regenerate video pixel clock accurately at the receiver side. In parallel to the video information, stereo audio and RS-232 control signals are transmitted as well.

  17. Using distance technologies to facilitate a learning collaborative to implement stagewise treatment.

    PubMed

    Covell, Nancy H; Foster, Forrest P; Margolies, Paul J; Lopez, Luis O; Dixon, Lisa B

    2015-06-01

    This report describes experiences and outcomes of an online learning collaborative focused on implementation of stagewise treatment. Eleven participating programs convened online monthly for a year. Between meetings, program staff created an implementation plan and programs collected performance indicator data, including assessment of staff knowledge of integrated treatment for people with co-occurring disorders, whether a person's current stage of treatment was documented in his or her chart, and whether the treatments were appropriate for the stage of treatment. Descriptive statistics were used to characterize performance indicators and feedback. Wilcoxon matched-pairs signed-rank tests examined changes in performance indicators over time. Program staff generally demonstrated significant improvements in performance indicators over time and rated the distance learning collaborative favorably. Distance learning collaboratives can be structured to provide opportunities for program staff to interact and learn from one another and to implement and sustain changes.

  18. Molecular analysis confirms the long-distance transport of Juniperus ashei pollen

    PubMed Central

    Mohanty, Rashmi Prava; Buchheim, Mark Alan; Anderson, James; Levetin, Estelle

    2017-01-01

    Although considered rare, airborne pollen can be deposited far from its place of origin under a confluence of favorable conditions. Temporally anomalous records of Cupressacean pollen collected from January air samples in London, Ontario, Canada have been cited as a new case of long-distance transport. Data on pollination season implicated Juniperus ashei (mountain cedar), with populations in central Texas and south central Oklahoma, as the nearest source of the Cupressacean pollen in the Canadian air samples. This finding is of special significance given the allergenicity of mountain cedar pollen. While microscopy is used extensively to identify particles in the air spora, pollen from all members of the Cupressaceae, including Juniperus, are morphologically indistinguishable. Consequently, we implemented a molecular approach to characterize Juniperus pollen using PCR in order to test the long-distance transport hypothesis. Our PCR results using species-specific primers confirmed that the anomalous Cupressacean pollen collected in Canada was from J. ashei. Forward trajectory analysis from source areas in Texas and the Arbuckle Mountains in Oklahoma and backward trajectory analysis from the destination area near London, Ontario were completed using models implemented in HYSPLIT4 (Hybrid Single-Particle Lagrangian Integrated Trajectory). Results from these trajectory analyses strongly supported the conclusion that the J. ashei pollen detected in Canada had its origins in Texas or Oklahoma. The results from the molecular findings are significant as they provide a new method to confirm the long-distance transport of pollen that bears allergenic importance. PMID:28273170

  19. Predictor variables of performance in recreational male long-distance inline skaters.

    PubMed

    Knechtle, Beat; Knechtle, Patrizia; Rüst, Christoph Alexander; Senn, Oliver; Rosemann, Thomas; Lepers, Romuald

    2011-06-01

    We investigated the associations between selected anthropometric and training characteristics with race time in 84 recreational male long-distance inline skaters at the longest inline marathon in Europe, the 'Inline One-eleven' over 111 km in Switzerland, using bi- and multivariate analysis. The mean (s) race time was 264 (41) min. The bivariate analysis showed that age (r = 0.30), body mass (r = 0.42), body mass index (r = 0.35), circumference of upper arm (r = 0.32), circumference of thigh (r = 0.29), circumference of calf (r = 0.38), skin-fold of thigh (r = 0.22), skin-fold of calf (r = 0.27), the sum of skin-folds (r = 0.43), percent body fat (r = 0.45), duration per training unit in inline skating (r = 0.33), and speed during training (r = -0.46) were significantly and positively correlated to race time. Stepwise multiple regression showed that duration per training unit (P = 0.003), age (P = 0.029) and percent body fat (P = 0.016) were the best correlated with race time. Race time in a long-distance inline race such as the 'Inline One-eleven' over 111 km with a mean race time of ∼260 min might be predicted by the following equation (r(2) = 0.41): Race time (min) = 114.91 + 0:51* (duration per training unit, min) + 0:85* (age, years) +3:78* (body fat, %) for recreational long-distance inline skaters.

  20. Frequent long-distance plant colonization in the changing Arctic.

    PubMed

    Alsos, Inger Greve; Eidesen, Pernille Bronken; Ehrich, Dorothee; Skrede, Inger; Westergaard, Kristine; Jacobsen, Gro Hilde; Landvik, Jon Y; Taberlet, Pierre; Brochmann, Christian

    2007-06-15

    The ability of species to track their ecological niche after climate change is a major source of uncertainty in predicting their future distribution. By analyzing DNA fingerprinting (amplified fragment-length polymorphism) of nine plant species, we show that long-distance colonization of a remote arctic archipelago, Svalbard, has occurred repeatedly and from several source regions. Propagules are likely carried by wind and drifting sea ice. The genetic effect of restricted colonization was strongly correlated with the temperature requirements of the species, indicating that establishment limits distribution more than dispersal. Thus, it may be appropriate to assume unlimited dispersal when predicting long-term range shifts in the Arctic.

  1. Long-distance signalling in plant defence.

    PubMed

    Heil, Martin; Ton, Jurriaan

    2008-06-01

    Plants use inducible defence mechanisms to fend off harmful organisms. Resistance that is induced in response to local attack is often expressed systemically, that is, in organs that are not yet damaged. In the search for translocated defence signals, biochemical studies follow the physical movement of putative signals, and grafting experiments use mutants that are impaired in the production or perception of these signals. Long-distance signals can directly activate defence or can prime for the stronger and faster induction of defence. Historically, research has focused on the vascular transport of signalling metabolites, but volatiles can play a crucial role as well. We compare the advantages and constraints of vascular and airborne signals for the plant, and discuss how they can act in synergy to achieve optimised resistance in distal plant parts.

  2. Long-distance gene flow and adaptation of forest trees to rapid climate change

    PubMed Central

    Kremer, Antoine; Ronce, Ophélie; Robledo-Arnuncio, Juan J; Guillaume, Frédéric; Bohrer, Gil; Nathan, Ran; Bridle, Jon R; Gomulkiewicz, Richard; Klein, Etienne K; Ritland, Kermit; Kuparinen, Anna; Gerber, Sophie; Schueler, Silvio

    2012-01-01

    Forest trees are the dominant species in many parts of the world and predicting how they might respond to climate change is a vital global concern. Trees are capable of long-distance gene flow, which can promote adaptive evolution in novel environments by increasing genetic variation for fitness. It is unclear, however, if this can compensate for maladaptive effects of gene flow and for the long-generation times of trees. We critically review data on the extent of long-distance gene flow and summarise theory that allows us to predict evolutionary responses of trees to climate change. Estimates of long-distance gene flow based both on direct observations and on genetic methods provide evidence that genes can move over spatial scales larger than habitat shifts predicted under climate change within one generation. Both theoretical and empirical data suggest that the positive effects of gene flow on adaptation may dominate in many instances. The balance of positive to negative consequences of gene flow may, however, differ for leading edge, core and rear sections of forest distributions. We propose future experimental and theoretical research that would better integrate dispersal biology with evolutionary quantitative genetics and improve predictions of tree responses to climate change. PMID:22372546

  3. Long-distance gene flow and adaptation of forest trees to rapid climate change.

    PubMed

    Kremer, Antoine; Ronce, Ophélie; Robledo-Arnuncio, Juan J; Guillaume, Frédéric; Bohrer, Gil; Nathan, Ran; Bridle, Jon R; Gomulkiewicz, Richard; Klein, Etienne K; Ritland, Kermit; Kuparinen, Anna; Gerber, Sophie; Schueler, Silvio

    2012-04-01

    Forest trees are the dominant species in many parts of the world and predicting how they might respond to climate change is a vital global concern. Trees are capable of long-distance gene flow, which can promote adaptive evolution in novel environments by increasing genetic variation for fitness. It is unclear, however, if this can compensate for maladaptive effects of gene flow and for the long-generation times of trees. We critically review data on the extent of long-distance gene flow and summarise theory that allows us to predict evolutionary responses of trees to climate change. Estimates of long-distance gene flow based both on direct observations and on genetic methods provide evidence that genes can move over spatial scales larger than habitat shifts predicted under climate change within one generation. Both theoretical and empirical data suggest that the positive effects of gene flow on adaptation may dominate in many instances. The balance of positive to negative consequences of gene flow may, however, differ for leading edge, core and rear sections of forest distributions. We propose future experimental and theoretical research that would better integrate dispersal biology with evolutionary quantitative genetics and improve predictions of tree responses to climate change. © 2012 Blackwell Publishing Ltd/CNRS.

  4. Long-Range Interaction Forces between Polymer-Supported Lipid Bilayer Membranes

    PubMed Central

    Seitz, Markus; Park, Chad K.; Wong, Joyce Y.

    2009-01-01

    Much of the short-range forces and structures of softly supported DMPC bilayers has been described previously. However, one interesting feature of the measured force–distance profile that remained unexplained is the presence of a long-range exponentially decaying repulsive force that is not observed between rigidly supported bilayers on solid mica substrate surfaces. This observation is discussed in detail here based on recent static and dynamic surface force experiments. The repulsive forces in the intermediate distance regime (mica–mica separations from 15 to 40 nm) are shown to be due not to an electrostatic force between the bilayers but to compression (deswelling) of the underlying soft polyelectrolyte layer, which may be thought of as a model cytoskeleton. The experimental data can be fit by simple theoretical models of polymer interactions from which the elastic properties of the polymer layer can be deduced. PMID:21359166

  5. From Radio, to Satellite, to M-Learning: Interactive Distance Education in Australia

    ERIC Educational Resources Information Center

    Crump, Stephen

    2013-01-01

    This paper provides reflections on M-learning as a form of "distance education," based on a summary of the findings of the Interactive Distance e-Learning (IDL) research project in rural and remote Australia under an Australian Research Council Linkage grant. This project was a joint undertaking between 3 government agencies and an…

  6. Interactive Distance e-Learning for Isolated Communities: Starting and Finishing the Jigsaw

    ERIC Educational Resources Information Center

    Crump, Stephen; Boylan, Colin

    2008-01-01

    This paper provides information on the background to the two pilot investigations into "interactive distance e-learning" [IDeL] following the introduction in New South Wales and in the Northern Territory of Australia of satellite-supported two-way broad-band internet services for school-age and adult distance education. The context is…

  7. Backscattering measurement of 6He on 209Bi: Critical interaction distance

    NASA Astrophysics Data System (ADS)

    Guimarães, V.; Kolata, J. J.; Aguilera, E. F.; Howard, A.; Roberts, A.; Becchetti, F. D.; Torres-Isea, R. O.; Riggins, A.; Febrarro, M.; Scarduelli, V.; de Faria, P. N.; Monteiro, D. S.; Huiza, J. F. P.; Arazi, A.; Hinnefeld, J.; Moro, A. M.; Rossi, E. S.; Morcelle, V.; Barioni, A.

    2016-06-01

    An elastic backscattering experiment has been performed at energies below the Coulomb barrier to investigate static and dynamic effects in the interaction of 6He with 209Bi. The measured cross sections are presented in terms of the d σ /d σR u t h ratio, as a function of the distance of closest approach on a Rutherford trajectory. The data are compared with a three-body CDCC calculation and good agreement is observed. In addition, the critical distance of interaction was extracted. A larger value was obtained for the exotic 6He nucleus as compared with the weakly bound 6Li and 9Be nuclei and the tightly bound 4He12C, and 16O nuclei.

  8. Generation of distributed W-states over long distances

    NASA Astrophysics Data System (ADS)

    Li, Yi

    2017-08-01

    Ultra-secure quantum communication between distant locations requires distributed entangled states between nodes. Various methodologies have been proposed to tackle this technological challenge, of which the so-called DLCZ protocol is the most promising and widely adopted scheme. This paper aims to extend this well-known protocol to a multi-node setting where the entangled W-state is generated between nodes over long distances. The generation of multipartite W-states is the foundation of quantum networks, paving the way for quantum communication and distributed quantum computation.

  9. Long-range energy transport in single supramolecular nanofibres at room temperature

    NASA Astrophysics Data System (ADS)

    Haedler, Andreas T.; Kreger, Klaus; Issac, Abey; Wittmann, Bernd; Kivala, Milan; Hammer, Natalie; Köhler, Jürgen; Schmidt, Hans-Werner; Hildner, Richard

    2015-07-01

    Efficient transport of excitation energy over long distances is a key process in light-harvesting systems, as well as in molecular electronics. However, in synthetic disordered organic materials, the exciton diffusion length is typically only around 10 nanometres (refs 4, 5), or about 50 nanometres in exceptional cases, a distance that is largely determined by the probability laws of incoherent exciton hopping. Only for highly ordered organic systems has the transport of excitation energy over macroscopic distances been reported--for example, for triplet excitons in anthracene single crystals at room temperature, as well as along single polydiacetylene chains embedded in their monomer crystalline matrix at cryogenic temperatures (at 10 kelvin, or -263 degrees Celsius). For supramolecular nanostructures, uniaxial long-range transport has not been demonstrated at room temperature. Here we show that individual self-assembled nanofibres with molecular-scale diameter efficiently transport singlet excitons at ambient conditions over more than four micrometres, a distance that is limited only by the fibre length. Our data suggest that this remarkable long-range transport is predominantly coherent. Such coherent long-range transport is achieved by one-dimensional self-assembly of supramolecular building blocks, based on carbonyl-bridged triarylamines, into well defined H-type aggregates (in which individual monomers are aligned cofacially) with substantial electronic interactions. These findings may facilitate the development of organic nanophotonic devices and quantum information technology.

  10. An interactive graphics system to facilitate finite element structural analysis

    NASA Technical Reports Server (NTRS)

    Burk, R. C.; Held, F. H.

    1973-01-01

    The characteristics of an interactive graphics systems to facilitate the finite element method of structural analysis are described. The finite element model analysis consists of three phases: (1) preprocessing (model generation), (2) problem solution, and (3) postprocessing (interpretation of results). The advantages of interactive graphics to finite element structural analysis are defined.

  11. Long-Distance and Proximal Romantic Relationship Satisfaction: Attachment and Closeness Predictors

    ERIC Educational Resources Information Center

    Roberts, Amber; Pistole, M. Carole

    2009-01-01

    Relationship satisfaction was examined in college student long-distance romantic relationships (LDRRs) and geographically proximal romantic relationships (PRRs). LDRR/PRR attachment style proportions and relationship satisfaction were similar. Multiple regression analyses revealed that low attachment avoidance contributed uniquely to high LDRR…

  12. Long-term Follow-up of Psilocybin-facilitated Smoking Cessation

    PubMed Central

    Johnson, Matthew W.; Garcia-Romeu, Albert; Griffiths, Roland R.

    2017-01-01

    Background A recent open-label pilot study (N=15) found that two to three moderate to high doses (20 and 30 mg/70 kg) of the serotonin 2A receptor agonist psilocybin, in combination with cognitive behavioral therapy (CBT) for smoking cessation, resulted in substantially higher 6-month smoking abstinence rates than are typically observed with other medications or CBT alone. Objectives To assess long-term effects of a psilocybin-facilitated smoking cessation program at ≥12 months after psilocybin administration. Methods The present report describes biologically verified smoking abstinence outcomes of the previous pilot study at ≥12 months, and related data on subjective effects of psilocybin. Results All 15 participants completed a 12-month follow-up, and 12 (80%) returned for a long-term (≥16 months) follow-up, with a mean interval of 30 months (range = 16 – 57 months) between target-quit date (i.e., first psilocybin session) and long-term follow-up. At 12-month follow-up, 10 participants (67%) were confirmed as smoking abstinent. At long-term follow-up, nine participants (60%) were confirmed as smoking abstinent. At 12-month follow-up 13 participants (86.7%) rated their psilocybin experiences among the 5 most personally meaningful and spiritually significant experiences of their lives. Conclusion These results suggest that in the context of a structured treatment program, psilocybin holds considerable promise in promoting long-term smoking abstinence. The present study adds to recent and historical evidence suggesting high success rates when using classic psychedelics in the treatment of addiction. Further research investigating psilocybin-facilitated treatment of substance use disorders is warranted. PMID:27441452

  13. Facilitating interaction, communication and collaboration in online courses

    NASA Astrophysics Data System (ADS)

    McNeil, Sara G.; Robin, Bernard R.; Miller, Robert M.

    2000-07-01

    As the Internet evolves into a truly world wide communications medium, the roles of faculty and students at institutions of higher learning are changing. Traditional face-to-face classes are being converted to an online setting, where materials from syllabi to lectures to assignments are available at the click of a mouse. New technological options are challenging and changing the very nature of teaching as faculty migrate from being deliverers of information to facilitators and mentors. Students are also undergoing a transformation from passive recipients to participants in an active learning environment. Interactions are at the heart of this revolution as students and faculty create new methodologies for the online classroom. New types of interactions are emerging between faculty and students, between students and other students and between students and the educational resources they are exploring. As the online teaching and learning environment expands and matures, new social and instructional interactions are replacing the traditional occurrences in face-to-face classrooms. New communication options are also evolving as a critical component of the online classroom. The shift from a synchronous to an asynchronous communication structure has also had a significant impact on the way students and faculty interact. The use of e-mail, listservs and web-based conferencing has given teachers and learners new flexibility and has fostered a climate where learning takes place wherever and whenever it is convenient. HyperGroups, a communication tool that was developed at the University of Houston, allows students and faculty to seamlessly participate in course-related discussions and easily share multimedia resources. This article explores the many issues associated with facilitating interaction, communication and collaboration in online courses.

  14. Testing the Münch hypothesis of long distance phloem transport in plants

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Knoblauch, Michael; Knoblauch, Jan; Mullendore, Daniel L.

    Long distance transport in plants occurs in sieve tubes of the phloem. The pressure flow hypothesis introduced by Ernst Münch in 1930 describes a mechanism of osmotically generated pressure differentials that are supposed to drive the movement of sugars and other solutes in the phloem, but this hypothesis has long faced major challenges. The key issue is whether the conductance of sieve tubes, including sieve plate pores, is sufficient to allow pressure flow. We show that with increasing distance between source and sink, sieve tube conductivity and turgor increases dramatically in Ipomoea nil. Our results provide strong support for themore » Münch hypothesis, while providing new tools for the investigation of one of the least understood plant tissues.« less

  15. Testing the Münch hypothesis of long distance phloem transport in plants

    DOE PAGES

    Knoblauch, Michael; Knoblauch, Jan; Mullendore, Daniel L.; ...

    2016-06-02

    Long distance transport in plants occurs in sieve tubes of the phloem. The pressure flow hypothesis introduced by Ernst Münch in 1930 describes a mechanism of osmotically generated pressure differentials that are supposed to drive the movement of sugars and other solutes in the phloem, but this hypothesis has long faced major challenges. The key issue is whether the conductance of sieve tubes, including sieve plate pores, is sufficient to allow pressure flow. We show that with increasing distance between source and sink, sieve tube conductivity and turgor increases dramatically in Ipomoea nil. Our results provide strong support for themore » Münch hypothesis, while providing new tools for the investigation of one of the least understood plant tissues.« less

  16. The Effects of Lighting and Interpersonal Distance on Counseling Interactions

    ERIC Educational Resources Information Center

    Dumont, Florent; Lecomte, Conrad

    1975-01-01

    Results showed a significant interactive effect of lighting and distance on the communication of empathy. Requests for reprints should be sent to F. Dumont, McGill University, 3700 McTavish Street, Montreal, P.Q., H3A 1Y2. (Author)

  17. Heat stroke risk for open-water swimmers during long-distance events.

    PubMed

    Macaluso, Filippo; Barone, Rosario; Isaacs, Ashwin W; Farina, Felicia; Morici, Giuseppe; Di Felice, Valentina

    2013-12-01

    Open-water swimming is a rapidly growing sport discipline worldwide, and clinical problems associated with long-distance swimming are now better recognized and managed more effectively. The most prevalent medical risk associated with an open-water swimming event is hypothermia; therefore, the Federation Internationale De Natation (FINA) has instituted 2 rules to reduce this occurrence related to the minimum water temperature and the time taken to complete the race. Another medical risk that is relevant to open-water swimmers is heat stroke, a condition that can easily go unnoticed. The purpose of this review is to shed light on this physiological phenomenon by examining the physiological response of swimmers during long-distance events, to define a maximum water temperature limit for competitions. We conclude that competing in water temperatures exceeding 33°C should be avoided. Copyright © 2013 Wilderness Medical Society. Published by Elsevier Inc. All rights reserved.

  18. Long Distance Learning.

    ERIC Educational Resources Information Center

    Villeneuve, Phyllis, Ed.

    1997-01-01

    This report, from the Faculty Association of Community and Technical Colleges (FACTC) in Washington, focuses on various distance learning courses offered by the state's two-year colleges. The report contains 16 articles from faculty members and students, including: (1) "The Emperor's New Tutor: A Confession" (Sydney Wallace Stegall); (2)…

  19. Long-range non-contact imaging photoplethysmography: cardiac pulse wave sensing at a distance

    NASA Astrophysics Data System (ADS)

    Blackford, Ethan B.; Estepp, Justin R.; Piasecki, Alyssa M.; Bowers, Margaret A.; Klosterman, Samantha L.

    2016-03-01

    Non-contact, imaging photoplethysmography uses photo-optical sensors to measure variations in light absorption, caused by blood volume pulsations, to assess cardiopulmonary parameters including pulse rate, pulse rate variability, and respiration rate. Recently, researchers have studied the applications and methodology of imaging photoplethysmography. Basic research has examined some of the variables affecting data quality and accuracy of imaging photoplethysmography including signal processing, imager parameters (e.g. frame rate and resolution), lighting conditions, subject motion, and subject skin tone. This technology may be beneficial for long term or continuous monitoring where contact measurements may be harmful (e.g. skin sensitivities) or where imperceptible or unobtrusive measurements are desirable. Using previously validated signal processing methods, we examined the effects of imager-to-subject distance on one-minute, windowed estimates of pulse rate. High-resolution video of 22, stationary participants was collected using an enthusiast-grade, mirrorless, digital camera equipped with a fully-manual, super-telephoto lens at distances of 25, 50, and 100 meters with simultaneous contact measurements of electrocardiography, and fingertip photoplethysmography. By comparison, previous studies have usually been conducted with imager-to-subject distances of up to only a few meters. Mean absolute error for one-minute, windowed, pulse rate estimates (compared to those derived from gold-standard electrocardiography) were 2.0, 4.1, and 10.9 beats per minute at distances of 25, 50, and 100 meters, respectively. Long-range imaging presents several unique challenges among which include decreased, observed light reflectance and smaller regions of interest. Nevertheless, these results demonstrate that accurate pulse rate measurements can be obtained from over long imager-to-participant distances given these constraints.

  20. Relationship between Achilles tendon properties and foot strike patterns in long-distance runners.

    PubMed

    Kubo, Keitaro; Miyazaki, Daisuke; Tanaka, Shigeharu; Shimoju, Shozo; Tsunoda, Naoya

    2015-01-01

    The purpose of this study was to investigate the relationship between Achilles tendon properties and foot strike patterns in long-distance runners. Forty-one highly trained male long-distance runners participated in this study. Elongation of the Achilles tendon and aponeurosis of the medial gastrocnemius muscle were measured using ultrasonography, while the participants performed ramp isometric plantar flexion up to the voluntary maximum. The relationship between the estimated muscle force and tendon elongation during the ascending phase was fit to a linear regression, the slope of which was defined as stiffness. In addition, the cross-sectional area of the Achilles tendon was measured using ultrasonography. Foot strike patterns (forefoot, midfoot and rearfoot) during running were determined at submaximal velocity (18 km · h(-1)) on a treadmill. The number of each foot strike runner was 12 for the forefoot (29.3%), 12 for the midfoot (29.3%) and 17 for the rearfoot (41.5%). No significant differences were observed in the variables measured for the Achilles tendon among the three groups. These results suggested that the foot strike pattern during running did not affect the morphological or mechanical properties of the Achilles tendon in long-distance runners.

  1. Testosterone levels in women and men who are single, in long-distance relationships, or same-city relationships.

    PubMed

    van Anders, Sari M; Watson, Neil V

    2007-02-01

    Research points to an association between testosterone (T) and partnering in some women and men, and this association has been interpreted as an effect of either relationship status (i.e. differences in relationship status lead to differences in T) or relationship orientation (i.e. T is associated with the likelihood of entering relationships). To address whether physical partner presence was associated with decreased T, we examined T levels in people (72 women; 49 men) who were single, in long-distance relationships, or in same-city relationships. No participants were using exogenous hormones, including hormonal contraceptives. Participants provided a saliva sample and responded to questions about their relationship status. Single men had higher T than long-distance and same-city partnered men, which supports the relationship orientation interpretation. In contrast, same-city partnered women had lower T than single women and women in long-distance relationships, which supports the relationship status interpretation. We conclude that physical partner presence is not necessary to see an association between partnering and hormones in men (since same-city and long-distance partnered men had similar T levels), but may be necessary in women (since same-city partnered women had lower T than long-distance partnered women).

  2. Long distance movement by a coyote within the Rocky Mountains

    Treesearch

    Jay A. Kolbe; John R. Squires

    2004-01-01

    We documented a long distance movement of a juvenile male coyote (Canis latrines) between February 2002 and February 2003. The radiocollared coyote, last located in west central Montana, U.S.A. traveled ≥310 km to southwestern Alberta, Canada where it was trapped. This is the longest documented movement by a coyote in western North America.

  3. High levels of effective long-distance dispersal may blur ecotypic divergence in a rare terrestrial orchid.

    PubMed

    Vanden Broeck, An; Van Landuyt, Wouter; Cox, Karen; De Bruyn, Luc; Gyselings, Ralf; Oostermeijer, Gerard; Valentin, Bertille; Bozic, Gregor; Dolinar, Branko; Illyés, Zoltán; Mergeay, Joachim

    2014-07-07

    Gene flow and adaptive divergence are key aspects of metapopulation dynamics and ecological speciation. Long-distance dispersal is hard to detect and few studies estimate dispersal in combination with adaptive divergence. The aim of this study was to investigate effective long-distance dispersal and adaptive divergence in the fen orchid (Liparis loeselii (L.) Rich.). We used amplified fragment length polymorphism (AFLP)-based assignment tests to quantify effective long-distance dispersal at two different regions in Northwest Europe. In addition, genomic divergence between fen orchid populations occupying two distinguishable habitats, wet dune slacks and alkaline fens, was investigated by a genome scan approach at different spatial scales (continental, landscape and regional) and based on 451 AFLP loci. We expected that different habitats would contribute to strong divergence and restricted gene flow resulting in isolation-by-adaptation. Instead, we found remarkably high levels of effective long-distance seed dispersal and low levels of adaptive divergence. At least 15% of the assigned individuals likely originated from among-population dispersal events with dispersal distances up to 220 km. Six (1.3%) 'outlier' loci, potentially reflecting local adaptation to habitat-type, were identified with high statistical support. Of these, only one (0.22%) was a replicated outlier in multiple independent dune-fen population comparisons and thus possibly reflecting truly parallel divergence. Signals of adaptation in response to habitat type were most evident at the scale of individual populations. The findings of this study suggest that the homogenizing effect of effective long-distance seed dispersal may overwhelm divergent selection associated to habitat type in fen orchids in Northwest Europe.

  4. High levels of effective long-distance dispersal may blur ecotypic divergence in a rare terrestrial orchid

    PubMed Central

    2014-01-01

    Background Gene flow and adaptive divergence are key aspects of metapopulation dynamics and ecological speciation. Long-distance dispersal is hard to detect and few studies estimate dispersal in combination with adaptive divergence. The aim of this study was to investigate effective long-distance dispersal and adaptive divergence in the fen orchid (Liparis loeselii (L.) Rich.). We used amplified fragment length polymorphism (AFLP)-based assignment tests to quantify effective long-distance dispersal at two different regions in Northwest Europe. In addition, genomic divergence between fen orchid populations occupying two distinguishable habitats, wet dune slacks and alkaline fens, was investigated by a genome scan approach at different spatial scales (continental, landscape and regional) and based on 451 AFLP loci. Results We expected that different habitats would contribute to strong divergence and restricted gene flow resulting in isolation-by-adaptation. Instead, we found remarkably high levels of effective long-distance seed dispersal and low levels of adaptive divergence. At least 15% of the assigned individuals likely originated from among-population dispersal events with dispersal distances up to 220 km. Six (1.3%) ‘outlier’ loci, potentially reflecting local adaptation to habitat-type, were identified with high statistical support. Of these, only one (0.22%) was a replicated outlier in multiple independent dune-fen population comparisons and thus possibly reflecting truly parallel divergence. Signals of adaptation in response to habitat type were most evident at the scale of individual populations. Conclusions The findings of this study suggest that the homogenizing effect of effective long-distance seed dispersal may overwhelm divergent selection associated to habitat type in fen orchids in Northwest Europe. PMID:24998243

  5. Collaborative Learning: A Critical Success Factor in Distance Education.

    ERIC Educational Resources Information Center

    Levin, David S.; Ben-Jacob, Marion G.

    This paper discusses the use of new technologies for distance learning-- including interactive video, computers, and the Internet-- at Mercy College (New York) and DePaul University (Illinois). The description of a course on discrete mathematics that is taught using the Mercy College Long-distance Instructional Network (MerLIN) focuses on the use…

  6. Long Distance Modulation of Disorder-to-Order Transitions in Protein Allostery.

    PubMed

    Wang, Jingheng; Custer, Gregory; Beckett, Dorothy; Matysiak, Silvina

    2017-08-29

    Elucidation of the molecular details of allosteric communication between distant sites in a protein is key to understanding and manipulating many biological regulatory processes. Although protein disorder is acknowledged to play an important thermodynamic role in allostery, the molecular mechanisms by which this disorder is harnessed for long distance communication are known for a limited number of systems. Transcription repression by the Escherichia coli biotin repressor, BirA, is allosterically activated by binding of the small molecule effector biotinoyl-5'-AMP. The effector acts by promoting BirA dimerization, which is a prerequisite for sequence-specific binding to the biotin biosynthetic operon operator sequence. A 30 Å distance separates the effector binding and dimerization surfaces in BirA, and previous studies indicate that allostery is mediated, in part, by disorder-to-order transitions on the two coupled sites. In this work, combined experimental and computational methods have been applied to investigate the molecular basis of allosteric communication in BirA. Double-mutant cycle analysis coupled with thermodynamic measurements indicates functional coupling between residues in disordered loops on the two distant surfaces. All atom molecular dynamics simulations reveal that this coupling occurs through long distance reciprocal modulation of the structure and dynamics of disorder-to-order transitions on the two surfaces.

  7. Long-term follow-up of a facilitated peer mentoring program.

    PubMed

    Mayer, Anita P; Blair, Janis E; Ko, Marcia G; Patel, Salma I; Files, Julia A

    2014-03-01

    Mentoring plays an important role in career success of academic medical faculty. New mentoring models such as peer mentoring have emerged. To evaluate the long-term impact of a facilitated peer mentoring program on academic achievements. Women faculty at the instructor or assistant professor rank were recruited to voluntarily participate in a facilitated peer mentoring program. Recruitment occurred over 3.8 years between 2005 and 2009. A 26-item questionnaire to assess academic skill, career satisfaction, and self-efficacy was administered before program participation and again with seven additional questions in 2011. Curriculum vitae were reviewed retrospectively to tally peer-reviewed publications, other academic activities, and promotions. Participants had long-term improvement in their perceived mastery of academic skills. Peer-reviewed publications, book chapters, abstracts, posters, and other academic activities increased when activities before the program were compared to those in the five years after program enrollment. At follow-up, participants reported positive perceptions of the program and 44% continued to work with their original peer mentor groups. Involvement in the facilitated peer mentoring program was associated with increased skills and academic activities for most participants. Future studies are needed to assess its applicability and success among various demographic groups in academic medicine.

  8. Testing the Münch hypothesis of long distance phloem transport in plants

    PubMed Central

    Knoblauch, Michael; Knoblauch, Jan; Mullendore, Daniel L; Savage, Jessica A; Babst, Benjamin A; Beecher, Sierra D; Dodgen, Adam C; Jensen, Kaare H; Holbrook, N Michele

    2016-01-01

    Long distance transport in plants occurs in sieve tubes of the phloem. The pressure flow hypothesis introduced by Ernst Münch in 1930 describes a mechanism of osmotically generated pressure differentials that are supposed to drive the movement of sugars and other solutes in the phloem, but this hypothesis has long faced major challenges. The key issue is whether the conductance of sieve tubes, including sieve plate pores, is sufficient to allow pressure flow. We show that with increasing distance between source and sink, sieve tube conductivity and turgor increases dramatically in Ipomoea nil. Our results provide strong support for the Münch hypothesis, while providing new tools for the investigation of one of the least understood plant tissues. DOI: http://dx.doi.org/10.7554/eLife.15341.001 PMID:27253062

  9. Unconditional security of quantum key distribution over arbitrarily long distances

    PubMed

    Lo; Chau

    1999-03-26

    Quantum key distribution is widely thought to offer unconditional security in communication between two users. Unfortunately, a widely accepted proof of its security in the presence of source, device, and channel noises has been missing. This long-standing problem is solved here by showing that, given fault-tolerant quantum computers, quantum key distribution over an arbitrarily long distance of a realistic noisy channel can be made unconditionally secure. The proof is reduced from a noisy quantum scheme to a noiseless quantum scheme and then from a noiseless quantum scheme to a noiseless classical scheme, which can then be tackled by classical probability theory.

  10. Spatial pattern of long-distance symplasmic transport and communication in trees

    PubMed Central

    Sokołowska, Katarzyna; Brysz, Alicja Maria; Zagórska-Marek, Beata

    2013-01-01

    Symplasmic short- and long-distance communication may be regulated at different levels of plant body organization. It depends on cell-to-cell transport modulated by plasmodesmata conductivity and frequency but above all on morphogenetic fields that integrate a plant at the supracellular level. Their control of physiological and developmental processes is especially important in trees, where the continuum consists of 3-dimensional systems of: 1) stem cells in cambium, and 2) living parenchyma cells in the secondary conductive tissues. We found that long-distance symplasmic transport in trees is spatially regulated. Uneven distribution of fluorescent tracer in cambial cells along the branches examined illustrates an unknown intrinsic phenomenon that can possibly be important for plant organism integration. Here we illustrate the spatial dynamics of symplasmic transport in cambium, test and exclude the role of callose in its regulation, and discuss the mechanism that could possibly be responsible for the maintenance of this spatial pattern. PMID:23989002

  11. Student-to-Student Interaction in Distance Education Classes: What Do Graduate Students Want?

    ERIC Educational Resources Information Center

    Moore, Gary E.; Warner, Wendy J.; Jones, David W. W.

    2016-01-01

    This research sought to determine if graduate students taking distance education classes desire student-to-student interaction. Over 200 graduate students who completed one or more distance education graduate classes in agricultural and extension education from North Carolina State University during the past three years were surveyed. While some…

  12. Geographic distance affects dispersal of the patchy distributed greater long-tailed hamster (Tscherskia triton).

    PubMed

    Xue, Huiliang; Zhong, Min; Xu, Jinhui; Xu, Laixiang

    2014-01-01

    Dispersal is a fundamental process in ecology influencing the genetic structure and the viability of populations. Understanding how variable factors influence the dispersal of the population is becoming an important question in animal ecology. To date, geographic distance and geographic barriers are often considered as main factors impacting dispersal, but their effects are variable depending on different conditions. In general, geographic barriers affect more significantly than geographic distance on dispersal. In rapidly expanding populations, however, geographic barriers have less effect on dispersal than geographic distance. The effects of both geographic distance and geographic barriers in low-density populations with patchy distributions are poorly understood. By using a panel of 10 microsatellite loci we investigated the genetic structure of three patchy-distributed populations of the Greater long-tailed hamster (Tscherskia triton) from Raoyang, Guan and Shunyi counties of the North China Plain. The results showed that (i) high genetic diversity and differentiation exist in three geographic populations with patchy distributions; (ii) gene flow occurs among these three populations with physical barriers of Beijing city and Hutuo River, which potentially restricted the dispersal of the animal; (iii) the gene flow is negatively correlated with the geographic distance, while the genetic distance shows the positive correlation. Our results suggest that the effect of the physical barriers is conditional-dependent, including barrier capacity or individual potentially dispersal ability. Geographic distance also acts as an important factor affecting dispersal for the patchy distributed geographic populations. So, gene flow is effective, even at relatively long distances, in balancing the effect of geographic barrier in this study.

  13. Sexual practices, myths and misconceptions among long distance truck drivers in North India.

    PubMed

    Sawal, N; Hans, G D R; Verma, G

    2016-07-01

    Long distance truck drivers and helpers constitute a high risk group for human immunodeficiency virus /acquired immune deficiency syndrome (HIV/AIDS). Despite increasing awareness of HIV/AIDS and safe sex practices, they still have a high incidence of new cases of HIV. This study carried out at an ART (anti-retroviral treatment) centre in North India aimed to evaluate the sexual myths and misconceptions prevalent among long distance drivers and helpers. This was a retrospective study carried out at apex ART centre. Data were collected retrospectively from ART records of 129 long distance Truck drivers and 68 helpers. Details of socio-demographic characteristics, contact with commercial sex workers (CSW'S), pattern of condom usage with CSW'S and factors influencing it were studied. We found that a significant number of drivers and helpers had sexual contact with CSW's and out of these, 30% of drivers and 50% of helpers reported not using condoms and instead resorting to methods like washing genitalia after sex with battery water/urine to avoid getting HIV. There was no significant relationship between pattern of condom usage and educational status, marital status and age. We also found that certain myths like sex with young CSW's was less likely to cause sexually transmitted diseases (STD's) and HIV were also widespread. Owing to continuing prevalence of such sexual myths, long distance truck drivers and helpers do not use condoms while having sex with CSW's as they feel that they can enjoy sex with CSW's and still stay protected against STD's/HIV. It is imperative that this battery water/urine antiseptic myth be specifically targeted for better HIV control in this high risk group. © The Author 2015. Published by Oxford University Press on behalf of the Association of Physicians. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  14. Phylogenetic Evidence of Long Distance Dispersal and Transmission of Piscine Reovirus (PRV) between Farmed and Wild Atlantic Salmon

    PubMed Central

    Garseth, Åse Helen; Ekrem, Torbjørn; Biering, Eirik

    2013-01-01

    The extent and effect of disease interaction and pathogen exchange between wild and farmed fish populations is an ongoing debate and an area of research that is difficult to explore. The objective of this study was to investigate pathogen transmission between farmed and wild Atlantic salmon (Salmo salar L.) populations in Norway by means of molecular epidemiology. Piscine reovirus (PRV) was selected as the model organism as it is widely distributed in both farmed and wild Atlantic salmon in Norway, and because infection not necessarily will lead to mortality through development of disease. A matrix comprised of PRV protein coding sequences S1, S2 and S4 from wild, hatchery-reared and farmed Atlantic salmon in addition to one sea-trout (Salmo trutta L.) was examined. Phylogenetic analyses based on maximum likelihood and Bayesian inference indicate long distance transport of PRV and exchange of virus between populations. The results are discussed in the context of Atlantic salmon ecology and the structure of the Norwegian salmon industry. We conclude that the lack of a geographical pattern in the phylogenetic trees is caused by extensive exchange of PRV. In addition, the detailed topography of the trees indicates long distance transportation of PRV. Through its size, structure and infection status, the Atlantic salmon farming industry has the capacity to play a central role in both long distance transportation and transmission of pathogens. Despite extensive migration, wild salmon probably play a minor role as they are fewer in numbers, appear at lower densities and are less likely to be infected. An open question is the relationship between the PRV sequences found in marine fish and those originating from salmon. PMID:24349221

  15. Winter habitat quality but not long-distance dispersal influences apparent reproductive success in a migratory bird.

    PubMed

    Rushing, Clark S; Marra, Peter P; Dudash, Michele R

    2016-05-01

    Long-distance breeding and natal dispersal play central roles in many ecological and evolutionary processes, including gene flow, population dynamics, range expansion, and individual responses to fluctuating biotic and abiotic conditions. However, the relative contribution of long-distance dispersal to these processes depends on the ability of dispersing individuals to successfully reproduce in their new environment. Unfortunately, due to the difficulties associated with tracking dispersal in the field, relatively little is known about its reproductive consequences. Furthermore, because reproductive success is influenced by a variety of processes, disentangling the influence of each of these processes is critical to understanding the direct consequences of dispersal. In this study, we used stable hydrogen and carbon isotopes to estimate long-distance dispersal and winter territory quality in a migratory bird, the American Redstart (Setophaga ruticilla). We then applied Aster life-history models to quantify the strength of influence of these factors on apparent reproductive success. We found no evidence that male or female reproductive success was lower for long-distance dispersers relative to non-dispersing individuals. In contrast, carry-over effects from the winter season did influence male, but not female, reproductive success. Use of Aster models further revealed that for adult males, winter territory quality influenced the number of offspring produced whereas for yearling males, high-quality winter territories were associated with higher mating and nesting success. These results suggest that although long-distance natal and breeding dispersal carry no immediate reproductive cost for American Redstarts, reproductive success in this species may ultimately be limited by the quality of winter habitat.

  16. Impaired Long Distance Functional Connectivity and Weighted Network Architecture in Alzheimer's Disease

    PubMed Central

    Liu, Yong; Yu, Chunshui; Zhang, Xinqing; Liu, Jieqiong; Duan, Yunyun; Alexander-Bloch, Aaron F.; Liu, Bing; Jiang, Tianzi; Bullmore, Ed

    2014-01-01

    Alzheimer's disease (AD) is increasingly recognized as a disconnection syndrome, which leads to cognitive impairment due to the disruption of functional activity across large networks or systems of interconnected brain regions. We explored abnormal functional magnetic resonance imaging (fMRI) resting-state dynamics, functional connectivity, and weighted functional networks, in a sample of patients with severe AD (N = 18) and age-matched healthy volunteers (N = 21). We found that patients had reduced amplitude and regional homogeneity of low-frequency fMRI oscillations, and reduced the strength of functional connectivity, in several regions previously described as components of the default mode network, for example, medial posterior parietal cortex and dorsal medial prefrontal cortex. In patients with severe AD, functional connectivity was particularly attenuated between regions that were separated by a greater physical distance; and loss of long distance connectivity was associated with less efficient global and nodal network topology. This profile of functional abnormality in severe AD was consistent with the results of a comparable analysis of data on 2 additional groups of patients with mild AD (N = 17) and amnestic mild cognitive impairment (MCI; N = 18). A greater degree of cognitive impairment, measured by the mini-mental state examination across all patient groups, was correlated with greater attenuation of functional connectivity, particularly over long connection distances, for example, between anterior and posterior components of the default mode network, and greater reduction of global and nodal network efficiency. These results indicate that neurodegenerative disruption of fMRI oscillations and connectivity in AD affects long-distance connections to hub nodes, with the consequent loss of network efficiency. This profile was evident also to a lesser degree in the patients with less severe cognitive impairment, indicating that the potential of resting

  17. High speed, long distance, data transmission multiplexing circuit

    DOEpatents

    Mariotti, Razvan

    1991-01-01

    A high speed serial data transmission multiplexing circuit, which is operable to accurately transmit data over long distances (up to 3 Km), and to multiplex, select and continuously display real time analog signals in a bandwidth from DC to 100 Khz. The circuit is made fault tolerant by use of a programmable flywheel algorithm, which enables the circuit to tolerate one transmission error before losing synchronization of the transmitted frames of data. A method of encoding and framing captured and transmitted data is used which has a low overhead and prevents some particular transmitted data patterns from locking an included detector/decoder circuit.

  18. Factors Affecting the Implementation of Policy 2450, Distance Education and the West Virginia Virtual School, as Perceived by Principals/Assistant Principals, Counselors, and Distance Learning Contacts and/or Course Facilitators

    ERIC Educational Resources Information Center

    Burdette, Keith R.

    2013-01-01

    This study examined the factors important to the implementation of West Virginia Board of Education Policy 2450, Distance Learning and the West Virginia Virtual School. The purpose of this study was to determine the factors that facilitated and impeded implementation of the policy, as perceived by principals/assistant principals, counselors, and…

  19. BKT phase transition in a 2D system with long-range dipole-dipole interaction

    NASA Astrophysics Data System (ADS)

    Fedichev, P. O.; Men'shikov, L. I.

    2012-01-01

    We consider phase transitions in 2D XY-like systems with long-range dipole-dipole interactions and demonstrate that BKT-type phase transition always occurs separating the ordered (ferroelectric) and the disordered (paraelectric) phases. The low-temperature phase corresponds to a thermal state with bound vortex-antivortex pairs characterized by linear attraction at large distances. Using the Maier-Schwabl topological charge model, we show that bound vortex pairs polarize and screen the vortex-antivortex interaction, leaving only the logarithmic attraction at sufficiently large separations between the vortices. At higher temperatures the pairs dissociate and the phase transition similar to BKT occurs, though at a larger temperature than in a system without the dipole-dipole interaction.

  20. Supervisor-employee power distance incompatibility, gender similarity, and relationship conflict: A test of interpersonal interaction theory.

    PubMed

    Graham, Katrina A; Dust, Scott B; Ziegert, Jonathan C

    2018-03-01

    According to interpersonal interaction theory, relational harmony surfaces when two individuals have compatible interaction styles. Building from this theory, we propose that supervisor-employee power distance orientation incompatibility will be related to employees' experience of higher levels of relationship conflict with their supervisors. Additionally, we propose an asymmetrical incongruence effect such that relationship conflict will be highest when supervisors are high in power distance and employees are low in power distance. Furthermore, we address calls in interpersonal interaction research for more direct attention to the social context of the dyadic interaction and explore the moderating effects of supervisor-employee gender (dis)similarity on the relationship between this incompatibility and conflict. We propose that supervisor-employee gender dissimilarity (e.g., male-female or female-male pairs) acts as a conditional moderator, neutralizing the power distance incongruence effect and the asymmetrical incongruence effect. Using 259 supervisor-employee dyads in the physical therapy industry, the hypotheses were generally supported. Theoretical and practical implications regarding the unique benefits of power distance compatibility and gender diversity in supervisor-employee dyads are discussed. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  1. Distance Education: Learner-Teacher Interaction and Time Spent by Teaching.

    ERIC Educational Resources Information Center

    Mahesh, Veena; McIsaac, Marina Stock

    This qualitative study examined the structure and interaction in an online course from the meaning-perspectives of the actors involved. Participants were a teacher and teaching assistant who taught a graduate course in distance education at Arizona State University, delivered through a computer conferencing system. Data collected included…

  2. Regulatory Enhancements, Infrastructure Modernization, and Connecticut's Interactive, Distance Learning Network.

    ERIC Educational Resources Information Center

    Pietras, Jesse John

    This paper presents an overview of the regulatory, technological, and economic status of interactive distance learning in Connecticut as it relates to the current and future provisioning of services by the telecommunications and cable television industries. The review is predicated upon the following questions: (1) What obligations should the…

  3. Generic Long-Range Interactions Between Passive Bodies in an Active Fluid.

    PubMed

    Baek, Yongjoo; Solon, Alexandre P; Xu, Xinpeng; Nikola, Nikolai; Kafri, Yariv

    2018-02-02

    A single nonspherical body placed in an active fluid generates currents via breaking of time-reversal symmetry. We show that, when two or more passive bodies are placed in an active fluid, these currents lead to long-range interactions. Using a multipole expansion, we characterize their leading-order behaviors in terms of single-body properties and show that they decay as a power law with the distance between the bodies, are anisotropic, and do not obey an action-reaction principle. The interactions lead to rich dynamics of the bodies, illustrated by the spontaneous synchronized rotation of pinned nonchiral bodies and the formation of traveling bound pairs. The occurrence of these phenomena depends on tunable properties of the bodies, thus opening new possibilities for self-assembly mediated by active fluids.

  4. A Bridge Over Turbulent Waters: Illustrating the Interaction Between Managerial Leaders and Facilitators When Implementing Research Evidence.

    PubMed

    van der Zijpp, Teatske Johanna; Niessen, Theo; Eldh, Ann Catrine; Hawkes, Claire; McMullan, Christel; Mockford, Carole; Wallin, Lars; McCormack, Brendan; Rycroft-Malone, Jo; Seers, Kate

    2016-02-01

    Emerging evidence focuses on the importance of the role of leadership in successfully transferring research evidence into practice. However, little is known about the interaction between managerial leaders and clinical leaders acting as facilitators (internal facilitators [IFs]) in this implementation process. To describe the interaction between managerial leaders and IFs and how this enabled or hindered the facilitation process of implementing urinary incontinence guideline recommendations in a local context in settings that provide long-term care to older people. Semistructured interviews with 105 managers and 22 IFs, collected for a realist process evaluation across four European countries informed this study. An interpretive data analysis unpacks interactions between managerial leaders and IFs. This study identified three themes that were important in the interactions between managerial leaders and IFs that could hinder or support the implementation process: "realising commitment"; "negotiating conditions"; and "encouragement to keep momentum going." The findings revealed that the continuous reciprocal relationships between IFs and managerial leaders influenced the progress of implementation, and could slow the process down or disrupt it. A metaphor of crossing a turbulent river by the "building of a bridge" emerged as one way of understanding the findings. Our findings illuminate a neglected area, the effects of relationships between key staff on implementing evidence into practice. Relational aspects of managerial and clinical leadership roles need greater consideration when planning guideline implementation and practice change. In order to support implementation, staff assigned as IFs as well as stakeholders like managers at all levels of an organisation should be engaged in realising commitment, negotiating conditions, and keeping momentum going. Thus, communication is crucial between all involved. © 2016 Sigma Theta Tau International.

  5. Age, training, and previous experience predict race performance in long-distance inline skaters, not anthropometry.

    PubMed

    Knechtle, Beat; Knechtle, Patrizia; Rüst, Christoph Alexander; Rosemann, Thomas; Lepers, Romuald

    2012-02-01

    The association of characteristics of anthropometry, training, and previous experience with race time in 84 recreational, long-distance, inline skaters at the longest inline marathon in Europe (111 km), the Inline One-eleven in Switzerland, was investigated to identify predictor variables for performance. Age, duration per training unit, and personal best time were the only three variables related to race time in a multiple regression, while none of the 16 anthropometric variables were related. Anthropometric characteristics seem to be of no importance for a fast race time in a long-distance inline skating race in contrast to training volume and previous experience, when controlled with covariates. Improving performance in a long-distance inline skating race might be related to a high training volume and previous race experience. Also, doing such a race requires a parallel psychological effort, mental stamina, focus, and persistence. This may be reflected in the preparation and training for the event. Future studies should investigate what motivates these athletes to train and compete.

  6. Ingestion of a Glucose Syrup Drink during long distance canoeing

    PubMed Central

    Green, L. F.; Bagley, R.

    1972-01-01

    The use of a drink containing glucose syrup and mineral salts has been compared with a placebo in a group of eight long-distance canoeists under simulated race conditions. The findings suggest that maintenance of blood glucose above fasting level during severe exercise prevents both a deterioration of performance and prolonged post-exercise exhaustion. There was no evidence to suggest that the benefits were psychological in nature.

  7. A comparison of distance education instructional methods in occupational therapy.

    PubMed

    Jedlicka, Janet S; Brown, Sarah W; Bunch, Ashley E; Jaffe, Lynn E

    2002-01-01

    The progression of technology is rapidly bringing new opportunities to students and academic institutions, resulting in a need for additional information to determine the most effective strategies for teaching distance learners. The purpose of this study was to compare the effectiveness of three instructional strategies (two-way interactive video and audio, chat rooms, and independent learning) and student preferences regarding instructional methods in a mental health programming distance learning course. Precourse and postcourse surveys were completed by 22 occupational therapy students enrolled in the course. Effectiveness of the teaching methods was determined based on the results of students' examinations. The findings indicated that there were no statistically significant differences in student performance on multiple-choice examinations using the three instructional methods. Of students, 77% indicated a preference for two-way interactive video and audio instruction. To provide effective education via distance learning methods, faculty members need to structure assignments that facilitate interaction and communication among learners. As distance education becomes more commonplace, it is important to identify the methods of instruction that are the most effective in delivering essential course content and the methods that provide the atmosphere most conducive to learning.

  8. Glucose uptake patterns in exercised skeletal muscles of elite male long-distance and short-distance runners.

    PubMed

    Tai, Suh-Jun; Liu, Ren-Shyan; Kuo, Ya-Chen; Hsu, Chi-Yang; Chen, Chi-Hsien

    2010-04-30

    The aim of this study was to determine glucose uptake patterns in exercised skeletal muscles of elite male long-distance and short-distance runners. Positron emission tomography (PET) using 18F-fluoro-2-deoxyglucose (FDG) was performed to determine the patterns of glucose uptake in lower limbs of short-distance (SD group, n=8) and long-distance (LD group, n=8) male runners after a modified 20 min Bruce treadmill test. Magnetic resonance imaging (MRI) was used to delineate the muscle groups in lower limbs. Muscle groups from hip, knee, and ankle movers were measured. The total FDG uptake and the standard uptake value (SUV) for each muscle group were compared between the 2 groups. For the SD and LD runners, the 2 major muscle groups utilizing glucose during running were knee extensors and ankle plantarflexors, which accounted for 49.3 +/- 8.1% (25.1 +/- 4.7% and 24.2 +/- 6.0%) of overall lower extremity glucose uptake for SD group, and 51.3 +/- 8.0% (27.2 +/- 2.7% and 24.0 +/- 8.1%) for LD group. No difference in muscle glucose uptake was noted for other muscle groups. For SD runners, the SUVs for the muscle groups varied from 0.49 +/- 0.27 for the ankle plantarflexors, to 0.20 +/- 0.08 for the hip flexor. For the LD runners, the highest and lowest SUVs were 0.43 +/- 0.15 for the ankle dorsiflexors and 0.21 +/- 0.19 for the hip. For SD and LD groups, no difference in muscle SUV was noted for the muscle groups. However, the SUV ratio between the ankle dorsiflexors and plantarflexors in the LD group was significantly greater than that in the SD group. We thus conclude that the major propelling muscle groups account for approximately 50% of lower limb glucose utilization during running. Thus, the other muscle groups involving maintenance of balance, limb deceleration, and shock absorption utilize an equal amount. This result provides a new insight into glucose distribution in skeletal muscle, suggesting that propellers and supporters are both energetically important

  9. Emergent ultra–long-range interactions between active particles in hybrid active–inactive systems

    PubMed Central

    Steimel, Joshua P.; Aragones, Juan L.; Hu, Helen; Qureshi, Naser; Alexander-Katz, Alfredo

    2016-01-01

    Particle–particle interactions determine the state of a system. Control over the range of such interactions as well as their magnitude has been an active area of research for decades due to the fundamental challenges it poses in science and technology. Very recently, effective interactions between active particles have gathered much attention as they can lead to out-of-equilibrium cooperative states such as flocking. Inspired by nature, where active living cells coexist with lifeless objects and structures, here we study the effective interactions that appear in systems composed of active and passive mixtures of colloids. Our systems are 2D colloidal monolayers composed primarily of passive (inactive) colloids, and a very small fraction of active (spinning) ferromagnetic colloids. We find an emergent ultra–long-range attractive interaction induced by the activity of the spinning particles and mediated by the elasticity of the passive medium. Interestingly, the appearance of such interaction depends on the spinning protocol and has a minimum actuation timescale below which no attraction is observed. Overall, these results clearly show that, in the presence of elastic components, active particles can interact across very long distances without any chemical modification of the environment. Such a mechanism might potentially be important for some biological systems and can be harnessed for newer developments in synthetic active soft materials. PMID:27071096

  10. Seasonal Food Scarcity Prompts Long-Distance Foraging by a Wild Social Bee.

    PubMed

    Pope, Nathaniel S; Jha, Shalene

    2018-01-01

    Foraging is an essential process for mobile animals, and its optimization serves as a foundational theory in ecology and evolution; however, drivers of foraging are rarely investigated across landscapes and seasons. Using a common bumblebee species from the western United States (Bombus vosnesenskii), we ask whether seasonal decreases in food resources prompt changes in foraging behavior and space use. We employ a unique integration of population genetic tools and spatially explicit foraging models to estimate foraging distances and rates of patch visitation for wild bumblebee colonies across three study regions and two seasons. By mapping the locations of 669 wild-caught individual foragers, we find substantial variation in colony-level foraging distances, often exhibiting a 60-fold difference within a study region. Our analysis of visitation rates indicates that foragers display a preference for destination patches with high floral cover and forage significantly farther for these patches, but only in the summer, when landscape-level resources are low. Overall, these results indicate that an increasing proportion of long-distance foraging bouts take place in the summer. Because wild bees are pollinators, their foraging dynamics are of urgent concern, given the potential impacts of global change on their movement and services. The behavioral shift toward long-distance foraging with seasonal declines in food resources suggests a novel, phenologically directed approach to landscape-level pollinator conservation and greater consideration of late-season floral resources in pollinator habitat management.

  11. Long-distance swimming by polar bears (Ursus maritimus) of the southern Beaufort Sea during years of extensive open water

    USGS Publications Warehouse

    2014-01-01

    Polar bears (Ursus maritimus Phipps, 1774) depend on sea ice for catching marine mammal prey. Recent sea-ice declines have been linked to reductions in body condition, survival, and population size. Reduced foraging opportunity is hypothesized to be the primary cause of sea-ice-linked declines, but the costs of travel through a deteriorated sea-ice environment also may be a factor. We used movement data from 52 adult female polar bears wearing Global Positioning System (GPS) collars, including some with dependent young, to document long-distance swimming (>50 km) by polar bears in the southern Beaufort and Chukchi seas. During 6 years (2004-2009), we identified 50 long-distance swims by 20 bears. Swim duration and distance ranged from 0.7 to 9.7 days (mean = 3.4 days) and 53.7 to 687.1 km (mean = 154.2 km), respectively. Frequency of swimming appeared to increase over the course of the study. We show that adult female polar bears and their cubs are capable of swimming long distances during periods when extensive areas of open water are present. However, long-distance swimming appears to have higher energetic demands than moving over sea ice. Our observations suggest long-distance swimming is a behavioral response to declining summer sea-ice conditions.

  12. Interactive Distance e-Learning for Isolated Communities: The Policy Footprint

    ERIC Educational Resources Information Center

    Crump, Stephen; Twyford, Kylie; Littler, Margaret

    2008-01-01

    This paper provides information on the policy strand of an investigation into the Australian Research Council Linkage research project into "interactive distance e-learning" [IDeL] following the introduction in New South Wales and in the Northern Territory of Australia of satellite-supported two-way broad-band internet services for…

  13. Protein-protein interaction site predictions with minimum covariance determinant and Mahalanobis distance.

    PubMed

    Qiu, Zhijun; Zhou, Bo; Yuan, Jiangfeng

    2017-11-21

    Protein-protein interaction site (PPIS) prediction must deal with the diversity of interaction sites that limits their prediction accuracy. Use of proteins with unknown or unidentified interactions can also lead to missing interfaces. Such data errors are often brought into the training dataset. In response to these two problems, we used the minimum covariance determinant (MCD) method to refine the training data to build a predictor with better performance, utilizing its ability of removing outliers. In order to predict test data in practice, a method based on Mahalanobis distance was devised to select proper test data as input for the predictor. With leave-one-validation and independent test, after the Mahalanobis distance screening, our method achieved higher performance according to Matthews correlation coefficient (MCC), although only a part of test data could be predicted. These results indicate that data refinement is an efficient approach to improve protein-protein interaction site prediction. By further optimizing our method, it is hopeful to develop predictors of better performance and wide range of application. Copyright © 2017 Elsevier Ltd. All rights reserved.

  14. Long-Distance Single Photon Transmission from a Trapped Ion via Quantum Frequency Conversion

    NASA Astrophysics Data System (ADS)

    Walker, Thomas; Miyanishi, Koichiro; Ikuta, Rikizo; Takahashi, Hiroki; Vartabi Kashanian, Samir; Tsujimoto, Yoshiaki; Hayasaka, Kazuhiro; Yamamoto, Takashi; Imoto, Nobuyuki; Keller, Matthias

    2018-05-01

    Trapped atomic ions are ideal single photon emitters with long-lived internal states which can be entangled with emitted photons. Coupling the ion to an optical cavity enables the efficient emission of single photons into a single spatial mode and grants control over their temporal shape. These features are key for quantum information processing and quantum communication. However, the photons emitted by these systems are unsuitable for long-distance transmission due to their wavelengths. Here we report the transmission of single photons from a single 40Ca+ ion coupled to an optical cavity over a 10 km optical fiber via frequency conversion from 866 nm to the telecom C band at 1530 nm. We observe nonclassical photon statistics of the direct cavity emission, the converted photons, and the 10 km transmitted photons, as well as the preservation of the photons' temporal shape throughout. This telecommunication-ready system can be a key component for long-distance quantum communication as well as future cloud quantum computation.

  15. Effect of clenbuterol on tracheal mucociliary transport in horses undergoing simulated long-distance transportation.

    PubMed

    Norton, J L; Jackson, K; Chen, J W; Boston, R; Nolen-Walston, R D

    2013-01-01

    Pneumonia is observed in horses after long-distance transportation in association with confinement of head position leading to reduction in tracheal mucociliary clearance rate (TMCR). Clenbuterol, a beta-2 agonist shown to increase TMCR in the horse, will ameliorate the effects of a fixed elevated head position on large airway contamination and inflammation in a model of long-distance transportation model. Six adult horses. A cross-over designed prospective study. Horses were maintained with a fixed elevated head position for 48 hours to simulate long-distance transport, and treated with clenbuterol (0.8 μg/kg PO q12h) or a placebo starting 12 hours before simulated transportation. TMCR was measured using a charcoal clearance technique. Data were collected at baseline and 48 hours, and included TMCR, tracheal wash cytology and quantitative culture, rectal temperature, CBC, fibrinogen, and serum TNFα, IL-10, and IL-2 levels. There was a 18-21 day washout between study arms, and data were analyzed using regression analysis and Wilcoxon rank-sum tests. Tracheal mucociliary clearance rate was significantly decreased after transportation in both treatment (P = .002) and placebo (P = .03) groups. There was a significant effect of treatment on TMCR, with the treatment group showing half the reduction in TMCR compared with the placebo group (P = .002). Other significant differences between before- and after-transportation samples occurred for serum fibrinogen, peripheral eosinophil count, quantitative culture, tracheal bacteria, and degenerate neutrophils, though no treatment effect was found. Treatment with clenbuterol modestly attenuates the deleterious effects of this long-distance transportation model on tracheal mucociliary clearance. Copyright © 2013 by the American College of Veterinary Internal Medicine.

  16. Using Design & Animation Concepts to Produce Animated Instructional Resources That Can Facilitate Open Distance Learning in Science and Technology Education

    ERIC Educational Resources Information Center

    Kwasu, Isaac Ali; Yalams, Simon Madugu; Ema, Ema

    2016-01-01

    This paper presents an outline on how teachers can use "The Design Process and Animation Techniques to produce animated instructional resources (AIR) which, can be used to facilitate Open Distance Learning in especially Science and Technology Education. A model of the Animated Instructional Resource was developed for the teaching of Human…

  17. Real-Time and Meter-Scale Absolute Distance Measurement by Frequency-Comb-Referenced Multi-Wavelength Interferometry.

    PubMed

    Wang, Guochao; Tan, Lilong; Yan, Shuhua

    2018-02-07

    We report on a frequency-comb-referenced absolute interferometer which instantly measures long distance by integrating multi-wavelength interferometry with direct synthetic wavelength interferometry. The reported interferometer utilizes four different wavelengths, simultaneously calibrated to the frequency comb of a femtosecond laser, to implement subwavelength distance measurement, while direct synthetic wavelength interferometry is elaborately introduced by launching a fifth wavelength to extend a non-ambiguous range for meter-scale measurement. A linearity test performed comparatively with a He-Ne laser interferometer shows a residual error of less than 70.8 nm in peak-to-valley over a 3 m distance, and a 10 h distance comparison is demonstrated to gain fractional deviations of ~3 × 10 -8 versus 3 m distance. Test results reveal that the presented absolute interferometer enables precise, stable, and long-term distance measurements and facilitates absolute positioning applications such as large-scale manufacturing and space missions.

  18. Impact of Distance Education via Interactive Videoconferencing on Students' Course Performance and Satisfaction

    ERIC Educational Resources Information Center

    Klibanov, Olga M.; Dolder, Christian; Anderson, Kevin; Kehr, Heather A.; Woods, J. Andrew

    2018-01-01

    The impact of distance education via interactive videoconferencing on pharmacy students' performance in a course was assessed after implementation of a distance campus. Students filled out a "Student Demographic Survey" and a "Precourse Knowledge Assessment" at the start of the course and a "Postcourse Knowledge…

  19. Local thermodynamics and the generalized Gibbs-Duhem equation in systems with long-range interactions.

    PubMed

    Latella, Ivan; Pérez-Madrid, Agustín

    2013-10-01

    The local thermodynamics of a system with long-range interactions in d dimensions is studied using the mean-field approximation. Long-range interactions are introduced through pair interaction potentials that decay as a power law in the interparticle distance. We compute the local entropy, Helmholtz free energy, and grand potential per particle in the microcanonical, canonical, and grand canonical ensembles, respectively. From the local entropy per particle we obtain the local equation of state of the system by using the condition of local thermodynamic equilibrium. This local equation of state has the form of the ideal gas equation of state, but with the density depending on the potential characterizing long-range interactions. By volume integration of the relation between the different thermodynamic potentials at the local level, we find the corresponding equation satisfied by the potentials at the global level. It is shown that the potential energy enters as a thermodynamic variable that modifies the global thermodynamic potentials. As a result, we find a generalized Gibbs-Duhem equation that relates the potential energy to the temperature, pressure, and chemical potential. For the marginal case where the power of the decaying interaction potential is equal to the dimension of the space, the usual Gibbs-Duhem equation is recovered. As examples of the application of this equation, we consider spatially uniform interaction potentials and the self-gravitating gas. We also point out a close relationship with the thermodynamics of small systems.

  20. External Versus Two Different Internal Foci of Attention in Long-Distance Throwing.

    PubMed

    Oki, Yuta; Kokubu, Masahiro; Nakagomi, Shiro

    2018-02-01

    The present study examined the influence of attentional focus on performance during a long-distance throwing task. Twelve participants executed three maximum-effort, long-distance baseball throwing attempts in three focus conditions: internal focus on wrist flexion (wrist internal focus), internal focus on the separation between pelvis and upper torso orientations (torso internal focus), and external focus on the ball path (external focus). Compared with the external focus and torso internal focus conditions, performance was poorer in the wrist internal focus condition. Performances were not different in the torso internal and external focus conditions. In addition, attentional focus affected the release angle of the ball but not its initial velocity. Our results reveal that the body part targeted for internal focus of attention and the forcefulness of the motor activity can be as important to motor performance as whether the attention is internal or external.

  1. Population genetic structure and long-distance dispersal of a recently expanding migratory bird.

    PubMed

    Ramos, Raül; Song, Gang; Navarro, Joan; Zhang, Ruiying; Symes, Craig T; Forero, Manuela G; Lei, Fumin

    2016-06-01

    Long-distance dispersal events and their derivable increases of genetic diversity have been highlighted as important ecological and evolutionary determinants that improve performances of range-expanding species. In the context of global environmental change, specific dispersal strategies have to be understood and foreseen if we like to prevent general biodiversity impoverishment or the spread of allochthonous diseases. We explored the genetic structure and potential population mixing on the recently range-expanding European bee-eater Merops apiaster. In addition, the species is suspected of harbouring and disseminating the most relevant disease for bees and apiculture, Nosema microsporidia. In agreement with complementary ringing recovery data and morphometric measurements, genetic results on two mitochondrial genes and 12 microsatellites showed a reasonably well-structured population partitioning along its breeding distribution. Microsatellite results indicated that not only did a few birds recently disperse long distance during their return migrations and change their natal breeding areas, but also that a group of allochthonous birds together founded a new colony. Although we did not provide evidence on the direct implication of birds in the widespread of Nosema parasites, our finding on the long-distance dispersal of bird flocks between remote breeding colonies adds concern about the role of European bee-eaters in the spread of such disease at a large, inter-continental scale. Copyright © 2016 Elsevier Inc. All rights reserved.

  2. SHD digital cinema distribution over a long distance network of Internet2

    NASA Astrophysics Data System (ADS)

    Yamaguchi, Takahiro; Shirai, Daisuke; Fujii, Tatsuya; Nomura, Mitsuru; Fujii, Tetsuro; Ono, Sadayasu

    2003-06-01

    We have developed a prototype SHD (Super High Definition) digital cinema distribution system that can store, transmit and display eight-million-pixel motion pictures that have the image quality of a 35-mm film movie. The system contains a video server, a real-time decoder, and a D-ILA projector. Using a gigabit Ethernet link and TCP/IP, the server transmits JPEG2000 compressed motion picture data streams to the decoder at transmission speeds as high as 300 Mbps. The received data streams are decompressed by the decoder, and then projected onto a screen via the projector. With this system, digital cinema contents can be distributed over a wide-area optical gigabit IP network. However, when digital cinema contents are delivered over long distances by using a gigabit IP network and TCP, the round-trip time increases and network throughput either stops rising or diminishes. In a long-distance SHD digital cinema transmission experiment performed on the Internet2 network in October 2002, we adopted enlargement of the TCP window, multiple TCP connections, and shaping function to control the data transmission quantity. As a result, we succeeded in transmitting the SHD digital cinema content data at about 300 Mbps between Chicago and Los Angeles, a distance of more than 3000 km.

  3. Mothers' Anxieties Versus the Effects of Long Distance Move on Children

    ERIC Educational Resources Information Center

    Barrett, Curtis L.; Noble, Helen

    1973-01-01

    Families moved long distances by a major interstate mover, reported on the effect of the moves on their 318 children using a questionnaire and the Louisville Behavior Check List (LBCL). No effect'' or a good'' effect of moving was reported for 81 per cent of the children. Parents with a bad'' attitude toward moving saw a negative effect on…

  4. The Development of Interactive Distance Learning in Taiwan: Challenges and Prospects.

    ERIC Educational Resources Information Center

    Chu, Clarence T.

    1999-01-01

    Describes three types of interactive distance-education systems under development in Taiwan: real-time multicast systems; virtual-classroom systems; and curriculum-on-demand systems. Discusses the use of telecommunications and computer technology in higher education, problems and challenges, and future prospects. (Author/LRW)

  5. Long-distance quantum communication with atomic ensembles and linear optics.

    PubMed

    Duan, L M; Lukin, M D; Cirac, J I; Zoller, P

    2001-11-22

    Quantum communication holds promise for absolutely secure transmission of secret messages and the faithful transfer of unknown quantum states. Photonic channels appear to be very attractive for the physical implementation of quantum communication. However, owing to losses and decoherence in the channel, the communication fidelity decreases exponentially with the channel length. Here we describe a scheme that allows the implementation of robust quantum communication over long lossy channels. The scheme involves laser manipulation of atomic ensembles, beam splitters, and single-photon detectors with moderate efficiencies, and is therefore compatible with current experimental technology. We show that the communication efficiency scales polynomially with the channel length, and hence the scheme should be operable over very long distances.

  6. Long-distance communication by specialized cellular projections during pigment pattern development and evolution

    PubMed Central

    Eom, Dae Seok; Bain, Emily J; Patterson, Larissa B; Grout, Megan E; Parichy, David M

    2015-01-01

    Changes in gene activity are essential for evolutionary diversification. Yet, elucidating the cellular behaviors that underlie modifications to adult form remains a profound challenge. We use neural crest-derived adult pigmentation of zebrafish and pearl danio to uncover cellular bases for alternative pattern states. We show that stripes in zebrafish require a novel class of thin, fast cellular projection to promote Delta-Notch signaling over long distances from cells of the xanthophore lineage to melanophores. Projections depended on microfilaments and microtubules, exhibited meandering trajectories, and stabilized on target cells to which they delivered membraneous vesicles. By contrast, the uniformly patterned pearl danio lacked such projections, concomitant with Colony stimulating factor 1-dependent changes in xanthophore differentiation that likely curtail signaling available to melanophores. Our study reveals a novel mechanism of cellular communication, roles for differentiation state heterogeneity in pigment cell interactions, and an unanticipated morphogenetic behavior contributing to a striking difference in adult form. DOI: http://dx.doi.org/10.7554/eLife.12401.001 PMID:26701906

  7. Impact of an HIV prevention intervention on condom use among long distance truckers in India.

    PubMed

    Juneja, Sachin; Rao Tirumalasetti, Vasudha; Mishra, Ram Manohar; Sethu, Shekhar; Singh, Indra Ramyash

    2013-03-01

    This paper examines the impact of three components of an HIV prevention program (mid-media, interpersonal communication, and project-run clinics) on consistent condom use by long distance truckers with paid and non-paid female partners in India. Data from 2,723 long distance truckers were analyzed using the propensity score matching approach. Based on utilization of services, the following categories of intervention exposure were derived: no exposure, exposure only to mid-media, exposure only to mid-media and interpersonal communication, exposure only to mid-media and project-run clinics, and exposure to all three intervention components. Compared to those who were not exposed to any intervention, exposure to mid-media alone increased consistent condom use with paid female partners by about ten percent. Exposure to mid-media and visits to project-run clinics increased consistent condom use with non-paid female partners by 26 %. These findings suggest that mid-media events and clinics were the most effective package of services to increase consistent condom use among the long distance truckers.

  8. Long-distance travel behaviours accelerate and aggravate the large-scale spatial spreading of infectious diseases.

    PubMed

    Xu, Zhijing; Zu, Zhenghu; Zheng, Tao; Zhang, Wendou; Xu, Qing; Liu, Jinjie

    2014-01-01

    The study analyses the role of long-distance travel behaviours on the large-scale spatial spreading of directly transmitted infectious diseases, focusing on two different travel types in terms of the travellers travelling to a specific group or not. For this purpose, we have formulated and analysed a metapopulation model in which the individuals in each subpopulation are organised into a scale-free contact network. The long-distance travellers between the subpopulations will temporarily change the network structure of the destination subpopulation through the "merging effects (MEs)," which indicates that the travellers will be regarded as either connected components or isolated nodes in the contact network. The results show that the presence of the MEs has constantly accelerated the transmission of the diseases and aggravated the outbreaks compared to the scenario in which the diversity of the long-distance travel types is arbitrarily discarded. Sensitivity analyses show that these results are relatively constant regarding a wide range variation of several model parameters. Our study has highlighted several important causes which could significantly affect the spatiotemporal disease dynamics neglected by the present studies.

  9. Interactions among resource partitioning, sampling effect, and facilitation on the biodiversity effect: a modeling approach.

    PubMed

    Flombaum, Pedro; Sala, Osvaldo E; Rastetter, Edward B

    2014-02-01

    Resource partitioning, facilitation, and sampling effect are the three mechanisms behind the biodiversity effect, which is depicted usually as the effect of plant-species richness on aboveground net primary production. These mechanisms operate simultaneously but their relative importance and interactions are difficult to unravel experimentally. Thus, niche differentiation and facilitation have been lumped together and separated from the sampling effect. Here, we propose three hypotheses about interactions among the three mechanisms and test them using a simulation model. The model simulated water movement through soil and vegetation, and net primary production mimicking the Patagonian steppe. Using the model, we created grass and shrub monocultures and mixtures, controlled root overlap and grass water-use efficiency (WUE) to simulate gradients of biodiversity, resource partitioning and facilitation. The presence of shrubs facilitated grass growth by increasing its WUE and in turn increased the sampling effect, whereas root overlap (resource partitioning) had, on average, no effect on sampling effect. Interestingly, resource partitioning and facilitation interacted so the effect of facilitation on sampling effect decreased as resource partitioning increased. Sampling effect was enhanced by the difference between the two functional groups in their efficiency in using resources. Morphological and physiological differences make one group outperform the other; once these differences were established further differences did not enhance the sampling effect. In addition, grass WUE and root overlap positively influence the biodiversity effect but showed no interactions.

  10. Role of co-occurring competition and facilitation in plant spacing hydrodynamics in water-limited environments

    PubMed Central

    2017-01-01

    Plant performance (i.e., fecundity, growth, survival) depends on an individual’s access to space and resources. At the community level, plant performance is reflected in observable vegetation patterning (i.e., spacing distance, density) often controlled by limiting resources. Resource availability is, in turn, strongly dependent on plant patterning mediated by competitive and facilitative plant–plant interactions. Co-occurring competition and facilitation has never been specifically investigated from a hydrodynamic perspective. To address this knowledge gap, and to overcome limitations of field studies, three intermediate-scale laboratory experiments were conducted using a climate-controlled wind tunnel–porous media test facility to simulate the soil–plant–atmosphere continuum. The spacing between two synthetic plants, a design consideration introduced by the authors in a recent publication, was varied between experiments; edaphic and mean atmospheric conditions were held constant. The strength of the above- and belowground plant–plant interactions changed with spacing distance, allowing the creation of a hydrodynamic conceptual model based on established ecological theories. Greatest soil water loss was observed for the experiment with the smallest spacing where competition dominated. Facilitation dominated at the intermediate spacing; little to no interactions were observed for the largest plant spacing. Results suggest that there exists an optimal spacing distance range that lowers plant environmental stress, thus improving plant performance through reduced atmospheric demand and conservation of available soil water. These findings may provide a foundation for improving our understanding of many climatological, ecohydrological, and hydrological problems pertaining to the hydrodynamics of water-limited environments where plant–plant interactions and community self-organization are important. PMID:28807999

  11. Role of co-occurring competition and facilitation in plant spacing hydrodynamics in water-limited environments.

    PubMed

    Trautz, Andrew C; Illangasekare, Tissa H; Rodriguez-Iturbe, Ignacio

    2017-08-29

    Plant performance (i.e., fecundity, growth, survival) depends on an individual's access to space and resources. At the community level, plant performance is reflected in observable vegetation patterning (i.e., spacing distance, density) often controlled by limiting resources. Resource availability is, in turn, strongly dependent on plant patterning mediated by competitive and facilitative plant-plant interactions. Co-occurring competition and facilitation has never been specifically investigated from a hydrodynamic perspective. To address this knowledge gap, and to overcome limitations of field studies, three intermediate-scale laboratory experiments were conducted using a climate-controlled wind tunnel-porous media test facility to simulate the soil-plant-atmosphere continuum. The spacing between two synthetic plants, a design consideration introduced by the authors in a recent publication, was varied between experiments; edaphic and mean atmospheric conditions were held constant. The strength of the above- and belowground plant-plant interactions changed with spacing distance, allowing the creation of a hydrodynamic conceptual model based on established ecological theories. Greatest soil water loss was observed for the experiment with the smallest spacing where competition dominated. Facilitation dominated at the intermediate spacing; little to no interactions were observed for the largest plant spacing. Results suggest that there exists an optimal spacing distance range that lowers plant environmental stress, thus improving plant performance through reduced atmospheric demand and conservation of available soil water. These findings may provide a foundation for improving our understanding of many climatological, ecohydrological, and hydrological problems pertaining to the hydrodynamics of water-limited environments where plant-plant interactions and community self-organization are important.

  12. Long-range interactions of hydrogen atoms in excited states. III. n S -1 S interactions for n ≥3

    NASA Astrophysics Data System (ADS)

    Adhikari, C. M.; Debierre, V.; Jentschura, U. D.

    2017-09-01

    The long-range interaction of excited neutral atoms has a number of interesting and surprising properties such as the prevalence of long-range oscillatory tails and the emergence of numerically large van der Waals C6 coefficients. Furthermore, the energetically quasidegenerate n P states require special attention and lead to mathematical subtleties. Here we analyze the interaction of excited hydrogen atoms in n S states (3 ≤n ≤12 ) with ground-state hydrogen atoms and find that the C6 coefficients roughly grow with the fourth power of the principal quantum number and can reach values in excess of 240 000 (in atomic units) for states with n =12 . The nonretarded van der Waals result is relevant to the distance range R ≪a0/α , where a0 is the Bohr radius and α is the fine-structure constant. The Casimir-Polder range encompasses the interatomic distance range a0/α ≪R ≪ℏ c /L , where L is the Lamb shift energy. In this range, the contribution of quasidegenerate excited n P states remains nonretarded and competes with the 1 /R2 and 1 /R4 tails of the pole terms, which are generated by lower-lying m P states with 2 ≤m ≤n -1 , due to virtual resonant emission. The dominant pole terms are also analyzed in the Lamb shift range R ≫ℏ c /L . The familiar 1 /R7 asymptotics from the usual Casimir-Polder theory is found to be completely irrelevant for the analysis of excited-state interactions. The calculations are carried out to high precision using computer algebra in order to handle a large number of terms in intermediate steps of the calculation for highly excited states.

  13. Modelling control of epidemics spreading by long-range interactions.

    PubMed

    Dybiec, Bartłomiej; Kleczkowski, Adam; Gilligan, Christopher A

    2009-10-06

    We have studied the spread of epidemics characterized by a mixture of local and non-local interactions. The infection spreads on a two-dimensional lattice with the fixed nearest neighbour connections. In addition, long-range dynamical links are formed by moving agents (vectors). Vectors perform random walks, with step length distributed according to a thick-tail distribution. Two distributions are considered in this paper, an alpha-stable distribution describing self-similar vector movement, yet characterized by an infinite variance and an exponential power characterized by a large but finite variance. Such long-range interactions are hard to track and make control of epidemics very difficult. We also allowed for cryptic infection, whereby an infected individual on the lattice can be infectious prior to showing any symptoms of infection or disease. To account for such cryptic spread, we considered a control strategy in which not only detected, i.e. symptomatic, individuals but also all individuals within a certain control neighbourhood are treated upon the detection of disease. We show that it is possible to eradicate the disease by using such purely local control measures, even in the presence of long-range jumps. In particular, we show that the success of local control and the choice of the optimal strategy depend in a non-trivial way on the dispersal patterns of the vectors. By characterizing these patterns using the stability index of the alpha-stable distribution to change the power-law behaviour or the exponent characterizing the decay of an exponential power distribution, we show that infection can be successfully contained using relatively small control neighbourhoods for two limiting cases for long-distance dispersal and for vectors that are much more limited in their dispersal range.

  14. Real-Time and Meter-Scale Absolute Distance Measurement by Frequency-Comb-Referenced Multi-Wavelength Interferometry

    PubMed Central

    Tan, Lilong; Yan, Shuhua

    2018-01-01

    We report on a frequency-comb-referenced absolute interferometer which instantly measures long distance by integrating multi-wavelength interferometry with direct synthetic wavelength interferometry. The reported interferometer utilizes four different wavelengths, simultaneously calibrated to the frequency comb of a femtosecond laser, to implement subwavelength distance measurement, while direct synthetic wavelength interferometry is elaborately introduced by launching a fifth wavelength to extend a non-ambiguous range for meter-scale measurement. A linearity test performed comparatively with a He–Ne laser interferometer shows a residual error of less than 70.8 nm in peak-to-valley over a 3 m distance, and a 10 h distance comparison is demonstrated to gain fractional deviations of ~3 × 10−8 versus 3 m distance. Test results reveal that the presented absolute interferometer enables precise, stable, and long-term distance measurements and facilitates absolute positioning applications such as large-scale manufacturing and space missions. PMID:29414897

  15. Foliar damage beyond species distributions is partly explained by distance dependent interactions with natural enemies.

    PubMed

    Katz, Daniel S W; Ibáñez, Inés

    2016-09-01

    Plant distributions are expected to shift in response to climate change, and range expansion dynamics will be shaped by the performance of individuals at the colonizing front. These plants will encounter new biotic communities beyond their range edges, and the net outcome of these encounters could profoundly affect colonization success. However, little is known about how biotic interactions vary across range edges and this has hindered efforts to predict changes in species distributions in response to climate change. In contrast, a rich literature documents how biotic interactions within species ranges vary according to distance to and density of conspecific individuals. Here, we test whether this framework can be extended to explain how biotic interactions differ beyond range edges, where conspecific adults are basically absent. To do so, we planted seven species of trees along a 450-km latitudinal gradient that crossed the current distributional range of five of these species and monitored foliar disease and invertebrate herbivory over 5 yr. Foliar disease and herbivory were analyzed as a function of distance to and density of conspecific and congeneric trees at several spatial scales. We found that within species ranges foliar disease was lower for seedlings that were farther from conspecific adults for Acer rubrum, Carya glabra, Quercus alba, and Robinia pseudoacacia. Beyond range edges, there was even less foliar disease for C. glabra, Q. alba, and R. pseudoacacia (A. rubrum was not planted outside its range). Liriodendron tulipifera did not experience reduced disease within or beyond its range. In contrast, Quercus velutina displayed significant but idiosyncratic patterns in disease at varying distances from conspecifics. Patterns of distance dependent herbivory across spatial scales was generally weak and in some cases negative (i.e., seedlings farther from conspecific adults had more herbivory). Overall, we conclude that differences in biotic

  16. Scorpio and Long-Distance Trade in Mesoamerica

    NASA Astrophysics Data System (ADS)

    Fahmel Beyer, Bernd

    2016-11-01

    This paper establishes a relationship between Scorpio and the astronomical group of the Ciudadela at Teotihuacan, linking them to the city's merchant elite. Its argument is based on a brief discussion of the alacrán and the context in which it appears in Prehispanic documents and art. Human figures with a scorpion-tail are emphasized because of their association with the merchant class and Venus. The iconography used to represent this star takes on many shapes, some of which were related to war. The origin of this symbol can be found on the southern coast of Guatemala, from where cacao was distributed to Oaxaca and the highlands. During the Postclassic the Soconusco was one of the most cherished domains of the Aztec, whose pochteca not only carried out long-distance trade but also had the power to solve or promote diplomatic conflicts.

  17. Long-Distance Romantic Relationships: Prevalence and Separation-Related Symptoms in College Students.

    ERIC Educational Resources Information Center

    Guldner, Gregory T.

    1996-01-01

    College students in long-distance romantic relationships (LDRs; n=164) were compared to 170 students in geographically proximal relationships (PRs) on measures of psychological distress. Those in LDRs reported significantly more symptoms of depression. Also, a prevalence estimate was obtained, and it supported previous research suggesting that 25%…

  18. Immunological, clinical, haematological and oxidative responses to long distance transportation in horses.

    PubMed

    Padalino, Barbara; Raidal, Sharanne Lee; Carter, Nicole; Celi, Pietro; Muscatello, Gary; Jeffcott, Leo; de Silva, Kumudika

    2017-12-01

    Horses are transported frequently and often over long distances. Transportation may represent a physiological stressor with consequential health and welfare implications. This study reports the effects of a long distance journey on immunological, clinical, haematological, inflammatory and oxidative parameters in an Experimental Group (EG) of ten horses, comparing them with six horses of similar age and breed used as a non-transported Control Group (CG). Clinical examination and blood sampling were performed twice on all horses: immediately after unloading for the EG, and at rest on the same day for the CG (day 1); at rest on the same day one week later for both groups (day 7). On day 1 EG horses showed increased heart and respiratory rates (P<0.01), rectal temperature (P<0.05), capillary refilling time (P<0.01), neutrophil numbers (P<0.01), serum albumin (P<0.01), plasma total antioxidant status (P<0.01), and a lower rate of mitogen induced proliferation of lymphocytes (P<0.05), in comparison with CG. On day 7 only an increase in total serum protein (P<0.05) and serum globulins (P<0.001) was seen in the EG. No difference in serum cortisol concentration was found. Long distance transportation induced an acute phase response impairing the cell-mediated immune response. Clinical examinations, including assessing CRT and body weight loss, and the monitoring of redox balance may be useful in evaluating the impact of extensive transport events on horses. A better understanding of the link between transportation stress, the immune system and the acute phase response is likely to inform strategies for enhancing the welfare of transported horses. Copyright © 2017 Elsevier Ltd. All rights reserved.

  19. Non-inverse-square force-distance law for long thin magnets-revisited.

    PubMed

    Darvell, Brian W; Gilding, Brian H

    2012-05-01

    It had previously been shown that the inverse-square law does not apply to the force-distance relationship in the case of a long, thin magnet with one end in close proximity to its image in a permeable plane when simple point-like poles are assumed. Treating the system instead as having a 'polar disc', arising from an assumed bundle of dipoles, led to a double integral that could only be evaluated numerically, and a relationship that still did not match observed behavior. Using an elaborate 'stretched' exponential polynomial to represent the position of an 'elastic' polar disc resulted in a fair representation of the physical response, but this was essentially merely the fitting of an arbitrary function. The present purpose was therefore to find an explicit formula for the force-distance relationship in the polar-disc problem and assess its fit to the previously obtained experimental data. Starting from Coulomb's law a corrected integral formula for the force-distance relationship was derived. The integral in this formula was evaluated explicitly using rescaling, changes of order of integration, reduction by symmetry, and change of variables. The resulting formula was then fitted to data that had been obtained for the force exerted by eighty-five rod-shaped magnets (Alnico V, 3 mm diameter, 170 mm long) perpendicular to a large steel plate, as a function of distance, at small separations (<5 mm). Subsequently, the fit of alternative functions was explored. An explicit formula in terms of elliptic integrals was obtained for the polar-disc problem. Despite the greater fidelity, this too was found not to fit the observed physical behavior. Given that failure, nevertheless a simple formula that conforms closely and parsimoniously to the actual magnet data was found. A key feature remains the marked departure from inverse-square behavior. The failure of the explicit formula to fit the data indicates an inadequate model of the physical system. Nonetheless it constitutes

  20. Strategies for improving performance in long duration events: Olympic distance triathlon.

    PubMed

    Hausswirth, Christophe; Brisswalter, Jeanick

    2008-01-01

    This review focuses on strategic aspects that may affect performance in a long-duration Olympic event, the Olympic distance triathlon. Given the variety of races during the Olympic Games triathlon, strategic aspects include improving technological features as well as energetics factors affecting overall triathlon performance. During the last decade, many studies have attempted to identify factors reducing the metabolic load associated (or not) with the development of fatigue process by analysing the relationship between metabolic and biomechanical factors with exercise duration. To date, a consensus exists about the benefit of adopting a drafting position during the swimming or the cycling part of the triathlon. Other potential strategic factors, such as the production of power output or the selection of cadence during the cycling or the running leg, are likely to affect the overall triathlon performance. Within this approach, pacing strategies are observed by elite athletes who swim or cycle in a sheltered position, inducing several changes of pace, intensity or stochastic shifts in the amplitude of the physiological responses. The analysis of these parameters appears to arouse some experimental and practical interest from researchers and coachers, especially for long-distance Olympic events.

  1. Application of digital image correlation for long-distance bridge deflection measurement

    NASA Astrophysics Data System (ADS)

    Tian, Long; Pan, Bing; Cai, Youfa; Liang, Hui; Zhao, Yan

    2013-06-01

    Due to its advantages of non-contact, full-field and high-resolution measurement, digital image correlation (DIC) method has gained wide acceptance and found numerous applications in the field of experimental mechanics. In this paper, the application of DIC for real-time long-distance bridge deflection detection in outdoor environments is studied. Bridge deflection measurement using DIC in outdoor environments is more challenging than regular DIC measurements performed under laboratory conditions. First, much more image noise due to variations in ambient light will be presented in the images recorded in outdoor environments. Second, how to select the target area becomes a key factor because long-distance imaging results in a large field of view of the test object. Finally, the image acquisition speed of the camera must be high enough (larger than 100 fps) to capture the real-time dynamic motion of a bridge. In this work, the above challenging issues are addressed and several improvements were made to DIC method. The applicability was demonstrated by real experiments. Experimental results indicate that the DIC method has great potentials in motion measurement in various large building structures.

  2. Distance Education for the Gifted and Talented: An Interactive Design Model.

    ERIC Educational Resources Information Center

    McKinnon, David H.; Nolan, C. J. Patrick

    1999-01-01

    Discusses development of an Australian distance-education cosmology course that employs an interactive design model and an extensive communication system. The way the model is used to organized, sequence, and deliver the course is explained. Discussion addresses how the model might be used to design other courses. (Author/CR)

  3. Celebrating Distance Teaching Innovations: The Certificate in Distance Teaching.

    ERIC Educational Resources Information Center

    Boylan, Colin; Tuovinen, Juhani

    Charles Sturt University (Riverina, Australia) has initiated the Certificate in Distance Teaching course for rural teachers working in a distance education setting to extend their understandings about rural and distance education topics. Two semester-long subjects constitute the course: pedagogy of distance teaching and organization of distance…

  4. Defying Food - How Distance Determines Monkeys' Ability to Inhibit Reaching for Food.

    PubMed

    Junghans, Astrid F; Sterck, Elisabeth H M; Overduin de Vries, Anne; Evers, Catharine; De Ridder, Denise T D

    2016-01-01

    Objects, such as food, in the environment automatically activate and facilitate affordances, the possibilities for motoric movements in interaction with the objects. Previous research has shown that affordance activation is contingent upon the distance of the object with only proximal objects activating potential movements. However, the effect of affordance-activating proximal objects on the ability to inhibit movements has been unaddressed. The current study addressed this question with two experiments on long-tailed macaques. In both experiments monkeys were situated behind a Plexiglass screen that prevented direct access to food placed right behind the screen. The food could only be reached via a detour through one of two holes on the sides of the screen. It was assessed whether monkeys' ability to inhibit the unsuccessful immediate reaching movement forward toward the food depended on the distance at which the food was presented. Results of both Experiments revealed that monkeys reached for the proximally positioned food significantly more than for the distally positioned food, despite this Plexiglass screen preventing successful obtainment of the food. The findings reveal the effect of proximal, affordance-activating objects on the ability to resist movements involved in interacting with the objects. Implications for humans, living in environments in which proximal, or accessible food is constantly available are discussed. The findings can contribute to an understanding of why resisting accessible food in the environment is often unsuccessful.

  5. Facilitation of contrast detection in near-peripheral vision.

    PubMed

    Giorgi, Robert G; Soong, Grace P; Woods, Russell L; Peli, Eli

    2004-12-01

    Foveal detection of a Gabor patch (target) is facilitated by collinear, displaced high-contrast flankers. Polat and Sagi reported that the same phenomenon occurred in the periphery, but no data were presented [Proc. Natl. Acad. Sci. 91 (1994) 1206]. Others have found no facilitation in a limited number of conditions tested. To resolve this apparent conflict, we measured lateral facilitation in the near-periphery using a range of stimulus parameters. We found facilitation for a range of target-flanker distances for peripheral eccentricities up to 6 degrees , but the magnitude of the effect was less than found in central vision. Facilitation varied across subjects and with spatial frequency. Flanker contrast had no effect over the range evaluated (10-80%). Equal facilitation was found for two global arrangements of the stimulus pattern. Facilitation was found using a temporal, but not a spatial two-alternative forced-choice paradigm, accounting for the different results among previous studies. This finding supports previous indications of the role of attention in altering such facilitation. The value of facilitation from lateral interactions for persons with central vision impairment, who have to shift their attention to a peripheral locus constantly, needs to be examined.

  6. Whitebark pine facilitation at treeline: potential interactions for disruption by an invasive pathogen.

    PubMed

    Tomback, Diana F; Blakeslee, Sarah C; Wagner, Aaron C; Wunder, Michael B; Resler, Lynn M; Pyatt, Jill C; Diaz, Soledad

    2016-08-01

    In stressful environments, facilitation often aids plant establishment, but invasive plant pathogens may potentially disrupt these interactions. In many treeline communities in the northern Rocky Mountains of the U.S. and Canada, Pinus albicaulis, a stress-tolerant pine, initiates tree islands at higher frequencies than other conifers - that is, leads to leeward tree establishment more frequently. The facilitation provided by a solitary (isolated) P. albicaulis leading to tree island initiation may be important for different life-history stages for leeward conifers, but it is not known which life-history stages are influenced and protection provided. However, P. albicaulis mortality from the non-native pathogen Cronartium ribicola potentially disrupts these facilitative interactions, reducing tree island initiation. In two Rocky Mountain eastern slope study areas, we experimentally examined fundamental plant-plant interactions which might facilitate tree island formation: the protection offered by P. albicaulis to leeward seed and seedling life-history stages, and to leeward krummholz conifers. In the latter case, we simulated mortality from C. ribicola for windward P. albicaulis to determine whether loss of P. albicaulis from C. ribicola impacts leeward conifers. Relative to other common solitary conifers at treeline, solitary P. albicaulis had higher abundance. More seeds germinated in leeward rock microsites than in conifer or exposed microsites, but the odds of cotyledon seedling survival during the growing season were highest in P. albicaulis microsites. Planted seedling survival was low among all microsites examined. Simulating death of windward P. albicaulis by C. ribicola reduced shoot growth of leeward trees. Loss of P. albicaulis to exotic disease may limit facilitation interactions and conifer community development at treeline and potentially impede upward movement as climate warms.

  7. Long distance, distributed gas sensing based on micro-nano fiber evanescent wave quartz-enhanced photoacoustic spectroscopy

    NASA Astrophysics Data System (ADS)

    He, Ying; Ma, Yufei; Tong, Yao; Yu, Xin; Peng, Zhenfang; Gao, Jing; Tittel, Frank K.

    2017-12-01

    A long distance, distributed gas sensing using the micro-nano fiber evanescent wave (FEW) quartz enhanced photoacoustic spectroscopy technique was demonstrated. Such a sensor scheme has the advantages of higher detection sensitivity, distributed gas sensing ability, lower cost, and a simpler fabrication procedure compared to conventional FEW gas sensors using a photonic crystal fiber or a tapered fiber with chemical sputtering. A 3 km single mode fiber with multiple tapers and an erbium doped fiber amplifier with an output optical power of 700 mW were employed to perform long distance, distributed gas measurements.

  8. The importance of supporting autonomy and perceived competence in facilitating long-term tobacco abstinence

    PubMed Central

    Williams, Geoffrey C.; Niemiec, Christopher P.; Patrick, Heather; Ryan, Richard M.; Deci, Edward L.

    2010-01-01

    Background The Public Health Service (PHS) Guideline for Treating Tobacco Use and Dependence (1) recommends supporting autonomy and perceived competence to facilitate tobacco abstinence. Purpose To evaluate the effectiveness of an intensive tobacco-dependence intervention based on self-determination theory (SDT) and intended to support autonomy and perceived competence in facilitating long-term tobacco abstinence. Methods One thousand and six adult smokers were recruited into a randomized cessation-induction trial. Community care participants received cessation pamphlets and information on local treatment programs. Intervention participants received the same materials and were asked to meet four times with counselors over six months to discuss their health in a manner intended to support autonomy and perceived competence. The primary outcome was 24-month prolonged abstinence from tobacco. The secondary outcome was 7-day point prevalence tobacco abstinence at 24 months post-intervention. Results Smokers in the intervention were more likely to attain both tobacco abstinence outcomes and these effects were partially mediated by change in both autonomous self-regulation and perceived competence from baseline to six months. Structural equation modeling confirmed the SDT model of health-behavior change in facilitating long-term tobacco abstinence. Conclusions An intervention based on SDT and consistent with the PHS Guideline, which was intended to support autonomy and perceived competence, facilitated long-term tobacco abstinence. PMID:19373517

  9. The importance of supporting autonomy and perceived competence in facilitating long-term tobacco abstinence.

    PubMed

    Williams, Geoffrey C; Niemiec, Christopher P; Patrick, Heather; Ryan, Richard M; Deci, Edward L

    2009-06-01

    The Public Health Service (PHS) Guideline for Treating Tobacco Use and Dependence (Fiore et al. 2000) recommends supporting autonomy and perceived competence to facilitate tobacco abstinence. The aim of the study was to evaluate the effectiveness of an intensive tobacco-dependence intervention based on self-determination theory (SDT) and intended to support autonomy and perceived competence in facilitating long-term tobacco abstinence. One thousand and six adult smokers were recruited into a randomized cessation-induction trial. Community care participants received cessation pamphlets and information on local treatment programs. Intervention participants received the same materials and were asked to meet four times with counselors over 6 months to discuss their health in a manner intended to support autonomy and perceived competence. The primary outcome was 24-month prolonged abstinence from tobacco. The secondary outcome was 7-day point prevalence tobacco abstinence at 24 months postintervention. Smokers in the intervention were more likely to attain both tobacco abstinence outcomes and these effects were partially mediated by change in both autonomous self-regulation and perceived competence from baseline to 6 months. Structural equation modeling confirmed the SDT model of health-behavior change in facilitating long-term tobacco abstinence. An intervention based on SDT and consistent with the PHS Guideline, which was intended to support autonomy and perceived competence, facilitated long-term tobacco abstinence.

  10. Long-distance dispersal of non-native pine bark beetles from host resources

    Treesearch

    Kevin Chase; Dave Kelly; Andrew M. Liebhold; Martin K.-F. Bader; Eckehard G. Brockerhoff

    2017-01-01

    Dispersal and host detection are behaviours promoting the spread of invading populations in a landscape matrix. In fragmented landscapes, the spatial arrangement of habitat structure affects the dispersal success of organisms. The aim of the present study was to determine the long distance dispersal capabilities of two non-native pine bark beetles (Hylurgus...

  11. The Virtual Learning Environment ROODA: An Institutional Project of Long Distance Education

    ERIC Educational Resources Information Center

    Behar, Patricia Alejandra; Leite, Silvia Meirelles

    2006-01-01

    This article describes ROODA (http://www.homer.nuted.edu.ufrgs.br), a virtual learning environment and one of the official Long Distance Education platforms that has been in use since 2005 at the Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Brazil. It is free software that integrates syncronous and assyncronous…

  12. Heterosis May Result in Selection Favouring the Products of Long-Distance Pollen Dispersal in Eucalyptus

    PubMed Central

    Costa e Silva, João; Potts, Brad M.; Lopez, Gustavo A.

    2014-01-01

    Using native trees from near the northern and southern extremities of the relatively continuous eastern distribution of Eucalyptus globulus in Tasmania, we compared the progenies derived from natural open-pollination (OP) with those generated from within-region and long-distance outcrossing. Controlled outcrossing amongst eight parents - with four parents from each of the northern and southern regions - was undertaken using a diallel mating scheme. The progeny were planted in two field trials located within the species native range in southern Tasmania, and their survival and diameter growth were monitored over a 13-year-period. The survival and growth performances of all controlled cross types exceeded those of the OP progenies, consistent with inbreeding depression due to a combination of selfing and bi-parental inbreeding. The poorer survival of the northern regional (♀N♂N) outcrosses compared with the local southern regional outcrosses (♀S♂S) indicated differential selection against the former. Despite this mal-adaptation of the non-local ♀N♂N crosses at both southern sites, the survival of the inter-regional hybrids (♀N♂S and ♀S♂N) was never significantly different from that of the local ♀S♂S crosses. Significant site-dependent heterosis was detected for the growth of the surviving long-distance hybrids. This was expressed as mid-parent heterosis, particularly at the more northern planting site. Heterosis increased with age, while the difference between the regional ♀N♂N and ♀S♂S crosses remained insignificant at any age at either site. Nevertheless, the results for growth suggest that the fitness of individuals derived from long-distance crossing may be better at the more northern of the planting sites. Our results demonstrate the potential for early-age assessments of pollen dispersal to underestimate realised gene flow, with local inbreeding under natural open-pollination resulting in selection favouring the products of

  13. Procedural justice climate and group power distance: an examination of cross-level interaction effects.

    PubMed

    Yang, Jixia; Mossholder, Kevin W; Peng, T K

    2007-05-01

    In this article, the authors extend research on the cross-level effects of procedural justice climate by theorizing and testing its interaction with group power distance. The results indicated that group power distance moderated the relationships between procedural justice climate and individual-level outcomes (organizational commitment and organization-directed citizenship behavior). More specifically, a larger group power distance was found to attenuate the positive cross-level effects of procedural justice climate. Implications for procedural justice climate research are discussed. 2007 APA, all rights reserved

  14. Trade-off between competition and facilitation defines gap colonization in mountains

    PubMed Central

    Lembrechts, Jonas J.; Milbau, Ann; Nijs, Ivan

    2015-01-01

    Recent experimental observations show that gap colonization in small-stature (e.g. grassland and dwarf shrubs) vegetation strongly depends on the abiotic conditions within them. At the same time, within-gap variation in biotic interactions such as competition and facilitation, caused by distance to the gap edge, would affect colonizer performance, but a theoretical framework to explore such patterns is missing. Here, we model how competition, facilitation and environmental conditions together determine the small-scale patterns of gap colonization along a cold gradient in mountains, by simulating colonizer survival in gaps of various sizes. Our model adds another dimension to the known effects of biotic interactions along a stress gradient by focussing on the trade-off between competition and facilitation in the within-gap environment. We show that this trade-off defines a peak in colonizer survival at a specific distance from the gap edge, which progressively shifts closer to the edge as the environment gets colder, ultimately leaving a large fraction of gaps unsuitable for colonization in facilitation-dominated systems. This is reinforced when vegetation size and temperature amelioration are manipulated simultaneously with temperature in order to simulate an elevational gradient more realistically. Interestingly, all other conditions being equal, the magnitude of the realized survival peak was always lower in large than in small gaps, making large gaps harder to colonize. The model is relevant to predict effects of non-native plant invasions and climate warming on colonization processes in mountains. PMID:26558706

  15. Long-distance dispersal and recolonization of a fire-destroyed niche by a mite-associated fungus.

    PubMed

    Aylward, Janneke; Dreyer, Léanne L; Steenkamp, Emma T; Wingfield, Michael J; Roets, Francois

    2015-04-01

    The Fynbos Biome in the Core Cape Subregion of South Africa is prone to recurrent fires that can clear vast areas of vegetation. Between periods of fire, ophiostomatoid fungi colonize the fruiting structures of serotinous Protea species through arthropod-mediated dispersal. Using microsatellite markers, this study considered the process whereby a Protea-associated ophiostomatoid fungus, Knoxdaviesia proteae, recolonizes a burnt area. The genetic diversity, composition and structure of fungal populations from young P. repens plants in a recently burnt area were compared to populations from the adjacent, unburnt Protea population. The only difference between K. proteae populations from the two areas was found in the number of private alleles, which was significantly higher in the unburnt population. The population structure, although weak, indicated that most K. proteae individuals from recently burnt areas originated from the unburnt population. However, individuals from unsampled source populations were also detected. This, together with the lack of isolation-by-distance across the landscape, suggested that long-distance dispersal is important for K. proteae to recolonize burnt areas. Similarly, the high level of gene flow and low differentiation observed between two distantly separated K. proteae populations also supported the existence of long-distance dispersal. The genetic cohesiveness of populations over long distances and the genetic diversity within populations could be attributed to frequent multiple fungal migration events mediated primarily by arthropods but, potentially, also by birds. Copyright © 2015 The British Mycological Society. Published by Elsevier Ltd. All rights reserved.

  16. Influence of Structure and Interaction on Student Achievement and Satisfaction in Web-Based Distance Learning

    ERIC Educational Resources Information Center

    Lee, Hye-Jung; Rha, Ilju

    2009-01-01

    This study examines the influence of instructional design and management style on student achievement and satisfaction in a web-based distance learning environment. From the literature review, two major instructional design and management styles in web-based distance education were conceptualized as structure and interpersonal interaction. To…

  17. Disturbance and density-dependent processes (competition and facilitation) influence the fine-scale genetic structure of a tree species' population.

    PubMed

    Fajardo, Alex; Torres-Díaz, Cristian; Till-Bottraud, Irène

    2016-01-01

    Disturbances, dispersal and biotic interactions are three major drivers of the spatial distribution of genotypes within populations, the last of which has been less studied than the other two. This study aimed to determine the role of competition and facilitation in the degree of conspecific genetic relatedness of nearby individuals of tree populations. It was expected that competition among conspecifics will lead to low relatedness, while facilitation will lead to high relatedness (selection for high relatedness within clusters). The stand structure and spatial genetic structure (SGS) of trees were examined within old-growth and second-growth forests (including multi-stemmed trees at the edge of forests) of Nothofagus pumilio following large-scale fires in Patagonia, Chile. Genetic spatial autocorrelations were computed on a spatially explicit sampling of the forests using five microsatellite loci. As biotic plant interactions occur among immediate neighbours, mean nearest neighbour distance (MNND) among trees was computed as a threshold for distinguishing the effects of disturbances and biotic interactions. All forests exhibited a significant SGS for distances greater than the MNND. The old-growth forest genetic and stand structure indicated gap recolonization from nearby trees (significantly related trees at distances between 4 and 10 m). At distances smaller than the MNND, trees of the second-growth interior forest showed significantly lower relatedness, suggesting a fading of the recolonization structure by competition, whereas the second-growth edge forest showed a positive and highly significant relatedness among trees (higher among stems of a cluster than among stems of different clusters), resulting from facilitation. Biotic interactions are shown to influence the genetic composition of a tree population. However, facilitation can only persist if individuals are related. Thus, the genetic composition in turn influences what type of biotic interactions

  18. Passive phloem loading and long-distance transport in a synthetic tree-on-a-chip.

    PubMed

    Comtet, Jean; Jensen, Kaare H; Turgeon, Robert; Stroock, Abraham D; Hosoi, A E

    2017-03-20

    Vascular plants rely on differences in osmotic pressure to export sugars from regions of synthesis (mature leaves) to sugar sinks (roots, fruits). In this process, known as Münch pressure flow, the loading of sugars from photosynthetic cells to the export conduit (the phloem) is crucial, as it sets the pressure head necessary to power long-distance transport. Whereas most herbaceous plants use active mechanisms to increase phloem sugar concentration above that of the photosynthetic cells, in most tree species, for which transport distances are largest, loading seems, counterintuitively, to occur by means of passive symplastic diffusion from the mesophyll to the phloem. Here, we use a synthetic microfluidic model of a passive loader to explore the non-linear dynamics that arise during export and determine the ability of passive loading to drive long-distance transport. We first demonstrate that in our device, the phloem concentration is set by the balance between the resistances to diffusive loading from the source and convective export through the phloem. Convection-limited export corresponds to classical models of Münch transport, where the phloem concentration is close to that of the source; in contrast, diffusion-limited export leads to small phloem concentrations and weak scaling of flow rates with hydraulic resistance. We then show that the effective regime of convection-limited export is predominant in plants with large transport resistances and low xylem pressures. Moreover, hydrostatic pressures developed in our synthetic passive loader can reach botanically relevant values as high as 10 bars. We conclude that passive loading is sufficient to drive long-distance transport in large plants, and that trees are well suited to take full advantage of passive phloem loading strategies.

  19. Antagonistic interactions peak at intermediate genetic distance in clinical and laboratory strains of Pseudomonas aeruginosa.

    PubMed

    Schoustra, Sijmen E; Dench, Jonathan; Dali, Rola; Aaron, Shawn D; Kassen, Rees

    2012-03-22

    Bacteria excrete costly toxins to defend their ecological niche. The evolution of such antagonistic interactions between individuals is expected to depend on both the social environment and the strength of resource competition. Antagonism is expected to be weak among highly similar genotypes because most individuals are immune to antagonistic agents and among dissimilar genotypes because these are unlikely to be competing for the same resources and antagonism should not yield much benefit. The strength of antagonism is therefore expected to peak at intermediate genetic distance. We studied the ability of laboratory strains of Pseudomonas aeruginosa to prevent growth of 55 different clinical P. aeruginosa isolates derived from cystic fibrosis patients. Genetic distance was determined using genetic fingerprints. We found that the strength of antagonism was maximal among genotypes of intermediate genetic distance and we show that genetic distance and resource use are linked. Our results suggest that the importance of social interactions like antagonism may be modulated by the strength of resource competition.

  20. The Effect of a 20 km Run on Appetite Regulation in Long Distance Runners

    PubMed Central

    Kojima, Chihiro; Ishibashi, Aya; Ebi, Kumiko; Goto, Kazushige

    2016-01-01

    The purpose of the present study was to investigate appetite-related hormonal responses and energy intake after a 20 km run in trained long distance runners. Twenty-three male long-distance runners completed two trials: either an exercise trial consisting of a 20 km outdoor run (EX) or a control trial with an identical period of rest (CON). Blood samples were collected to determine plasma acylated ghrelin, peptide YY3-36 (PYY3-36) and other hormonal and metabolite concentrations. Energy intake during a buffet test meal was also measured 30 min after the exercise or rest periods. Although plasma acylated ghrelin concentrations were significantly decreased after the 20 km run (p < 0.05), plasma PYY3-36 did not change significantly following exercise. Absolute energy intake during the buffet test meal in EX (1325 ± 55 kcal) was significantly lower than that in CON (1529 ± 55 kcal), and there was a relatively large degree of individual variability for exercise-induced changes in energy intake (−40.2% to 12.8%). However, exercise-induced changes in energy intake were not associated with plasma acylated ghrelin or PYY3-36 responses. The results demonstrated that a 20 km run significantly decreased plasma acylated ghrelin concentrations and absolute energy intake among well-trained long distance runners. PMID:27792164

  1. Long distance spin communication in chemical vapour deposited graphene

    NASA Astrophysics Data System (ADS)

    Kamalakar, M. Venkata; Groenveld, Christiaan; Dankert, André; Dash, Saroj P.

    2015-04-01

    Graphene is an ideal medium for long-distance spin communication in future spintronic technologies. So far, the prospect is limited by the smaller sizes of exfoliated graphene flakes and lower spin transport properties of large-area chemical vapour-deposited (CVD) graphene. Here we demonstrate a high spintronic performance in CVD graphene on SiO2/Si substrate at room temperature. We show pure spin transport and precession over long channel lengths extending up to 16 μm with a spin lifetime of 1.2 ns and a spin diffusion length ~6 μm at room temperature. These spin parameters are up to six times higher than previous reports and highest at room temperature for any form of pristine graphene on industrial standard SiO2/Si substrates. Our detailed investigation reinforces the observed performance in CVD graphene over wafer scale and opens up new prospects for the development of lateral spin-based memory and logic applications.

  2. Seed dispersal at alpine treeline: long distance dispersal maintains alpine treelines

    NASA Astrophysics Data System (ADS)

    Johnson, J. S.; Gaddis, K. D.; Cairns, D. M.; Krutovsky, K.

    2016-12-01

    Alpine treelines are expected to advance to higher elevations in conjunction with global warming. Nevertheless, the importance of reproductive method and seed dispersal distances at the alpine treeline ecotone remains unresolved. We address two research questions at mountain hemlock treelines on the Kenai Peninsula, Alaska: (1) What is the primary mode of reproduction, and (2) are recruits derived from local treeline populations or are they arriving from more distant seed sources? We addressed our research questions by exhaustively sampling mountain hemlock individuals along a single mountain slope and then genotyped DNA single nucleotide polymorphisms using a genotyping by sequencing approach (ddRAD Seq). First we assessed mode of reproduction by determining the proportion of sampled individuals with identical multilocus genotypes that are the product of clonal reproduction. Second, we used a categorical allocation based parentage analysis to identify parent-offspring pairs, so that the proportion of treeline reproduction events could be quantified spatially and dispersal distance measured. We identified sexual reproduction as the primary mode of reproduction at our study site. Seedling establishment was characterized by extensive cryptic seed dispersal and gene flow into the ecotone. The average dispersal distance was 73 meters with long distance dispersal identified as dispersal occurring at distances greater than 450 meters. We show that production of seeds within the alpine treeline ecotone is not a necessary requirement for treelines to advance to higher elevations in response to climate change. The extensive cryptic seed dispersal and gene flow into the alpine treeline ecotone is likely sufficient to propel the ecotone higher under more favorable climate.

  3. Distinct palisade tissue development processes promoted by leaf autonomous signalling and long-distance signalling in Arabidopsis thaliana.

    PubMed

    Munekage, Yuri Nakajima; Inoue, Shio; Yoneda, Yuki; Yokota, Akiho

    2015-06-01

    Plants develop palisade tissue consisting of cylindrical mesophyll cells located at the adaxial side of leaves in response to high light. To understand high light signalling in palisade tissue development, we investigated leaf autonomous and long-distance signal responses of palisade tissue development using Arabidopsis thaliana. Illumination of a developing leaf with high light induced cell height elongation, whereas illumination of mature leaves with high light increased cell density and suppressed cell width expansion in palisade tissue of new leaves. Examination using phototropin1 phototropin2 showed that blue light signalling mediated by phototropins was involved in cell height elongation of the leaf autonomous response rather than the cell density increase induced by long-distance signalling. Hydrogen peroxide treatment induced cylindrical palisade tissue cell formation in both a leaf autonomous and long-distance manner, suggesting involvement of oxidative signals. Although constitutive expression of transcription factors involved in systemic-acquired acclimation to excess light, ZAT10 and ZAT12, induced cylindrical palisade tissue cell formation, knockout of these genes did not affect cylindrical palisade tissue cell formation. We conclude that two distinct signalling pathways - leaf autonomous signalling mostly dependent on blue light signalling and long-distance signalling from mature leaves that sense high light and oxidative stress - control palisade tissue development in A. thaliana. © 2014 John Wiley & Sons Ltd.

  4. Long-distance dispersal of eastern spruce budworm in Minnesota (USA) via the atmospheric pathway

    Treesearch

    Brian Sturtevant; Gary Achtemeier; Dean Anderson; Joseph Charney; Barry Cooke

    2011-01-01

    Long-distance dispersal is thought to play an important role in synchronizing disparate populations of forest insect defoliators, but its importance relative to other factors remains unclear due to the difficulty of quantifying dispersal.

  5. Measurement of the phase difference between short- and long-distance amplitudes in the [Formula: see text] decay.

    PubMed

    Aaij, R; Adeva, B; Adinolfi, M; Ajaltouni, Z; Akar, S; Albrecht, J; Alessio, F; Alexander, M; Ali, S; Alkhazov, G; Alvarez Cartelle, P; Alves, A A; Amato, S; Amerio, S; Amhis, Y; An, L; Anderlini, L; Andreassi, G; Andreotti, M; Andrews, J E; Appleby, R B; Archilli, F; d'Argent, P; Arnau Romeu, J; Artamonov, A; Artuso, M; Aslanides, E; Auriemma, G; Baalouch, M; Babuschkin, I; Bachmann, S; Back, J J; Badalov, A; Baesso, C; Baker, S; Balagura, V; Baldini, W; Barlow, R J; Barschel, C; Barsuk, S; Barter, W; Baszczyk, M; Batozskaya, V; Batsukh, B; Battista, V; Bay, A; Beaucourt, L; Beddow, J; Bedeschi, F; Bediaga, I; Bel, L J; Bellee, V; Belloli, N; Belous, K; Belyaev, I; Ben-Haim, E; Bencivenni, G; Benson, S; Berezhnoy, A; Bernet, R; Bertolin, A; Betancourt, C; Betti, F; Bettler, M-O; van Beuzekom, M; Bezshyiko, Ia; Bifani, S; Billoir, P; Bird, T; Birnkraut, A; Bitadze, A; Bizzeti, A; Blake, T; Blanc, F; Blouw, J; Blusk, S; Bocci, V; Boettcher, T; Bondar, A; Bondar, N; Bonivento, W; Bordyuzhin, I; Borgheresi, A; Borghi, S; Borisyak, M; Borsato, M; Bossu, F; Boubdir, M; Bowcock, T J V; Bowen, E; Bozzi, C; Braun, S; Britsch, M; Britton, T; Brodzicka, J; Buchanan, E; Burr, C; Bursche, A; Buytaert, J; Cadeddu, S; Calabrese, R; Calvi, M; Calvo Gomez, M; Camboni, A; Campana, P; Campora Perez, D H; Capriotti, L; Carbone, A; Carboni, G; Cardinale, R; Cardini, A; Carniti, P; Carson, L; Carvalho Akiba, K; Casse, G; Cassina, L; Castillo Garcia, L; Cattaneo, M; Cavallero, G; Cenci, R; Chamont, D; Charles, M; Charpentier, Ph; Chatzikonstantinidis, G; Chefdeville, M; Chen, S; Cheung, S-F; Chobanova, V; Chrzaszcz, M; Cid Vidal, X; Ciezarek, G; Clarke, P E L; Clemencic, M; Cliff, H V; Closier, J; Coco, V; Cogan, J; Cogneras, E; Cogoni, V; Cojocariu, L; Collazuol, G; Collins, P; Comerma-Montells, A; Contu, A; Cook, A; Coombs, G; Coquereau, S; Corti, G; Corvo, M; Costa Sobral, C M; Couturier, B; Cowan, G A; Craik, D C; Crocombe, A; Cruz Torres, M; Cunliffe, S; Currie, R; D'Ambrosio, C; Da Cunha Marinho, F; Dall'Occo, E; Dalseno, J; David, P N Y; Davis, A; De Bruyn, K; De Capua, S; De Cian, M; De Miranda, J M; De Paula, L; De Serio, M; De Simone, P; Dean, C-T; Decamp, D; Deckenhoff, M; Del Buono, L; Demmer, M; Dendek, A; Derkach, D; Deschamps, O; Dettori, F; Dey, B; Di Canto, A; Dijkstra, H; Dordei, F; Dorigo, M; Dosil Suárez, A; Dovbnya, A; Dreimanis, K; Dufour, L; Dujany, G; Dungs, K; Durante, P; Dzhelyadin, R; Dziurda, A; Dzyuba, A; Déléage, N; Easo, S; Ebert, M; Egede, U; Egorychev, V; Eidelman, S; Eisenhardt, S; Eitschberger, U; Ekelhof, R; Eklund, L; Ely, S; Esen, S; Evans, H M; Evans, T; Falabella, A; Farley, N; Farry, S; Fay, R; Fazzini, D; Ferguson, D; Fernandez Prieto, A; Ferrari, F; Ferreira Rodrigues, F; Ferro-Luzzi, M; Filippov, S; Fini, R A; Fiore, M; Fiorini, M; Firlej, M; Fitzpatrick, C; Fiutowski, T; Fleuret, F; Fohl, K; Fontana, M; Fontanelli, F; Forshaw, D C; Forty, R; Franco Lima, V; Frank, M; Frei, C; Fu, J; Funk, W; Furfaro, E; Färber, C; Gallas Torreira, A; Galli, D; Gallorini, S; Gambetta, S; Gandelman, M; Gandini, P; Gao, Y; Garcia Martin, L M; García Pardiñas, J; Garra Tico, J; Garrido, L; Garsed, P J; Gascon, D; Gaspar, C; Gavardi, L; Gazzoni, G; Gerick, D; Gersabeck, E; Gersabeck, M; Gershon, T; Ghez, Ph; Gianì, S; Gibson, V; Girard, O G; Giubega, L; Gizdov, K; Gligorov, V V; Golubkov, D; Golutvin, A; Gomes, A; Gorelov, I V; Gotti, C; Graciani Diaz, R; Granado Cardoso, L A; Graugés, E; Graverini, E; Graziani, G; Grecu, A; Griffith, P; Grillo, L; Gruberg Cazon, B R; Grünberg, O; Gushchin, E; Guz, Yu; Gys, T; Göbel, C; Hadavizadeh, T; Hadjivasiliou, C; Haefeli, G; Haen, C; Haines, S C; Hall, S; Hamilton, B; Han, X; Hansmann-Menzemer, S; Harnew, N; Harnew, S T; Harrison, J; Hatch, M; He, J; Head, T; Heister, A; Hennessy, K; Henrard, P; Henry, L; van Herwijnen, E; Heß, M; Hicheur, A; Hill, D; Hombach, C; Hopchev, H; Hulsbergen, W; Humair, T; Hushchyn, M; Hutchcroft, D; Idzik, M; Ilten, P; Jacobsson, R; Jaeger, A; Jalocha, J; Jans, E; Jawahery, A; Jiang, F; John, M; Johnson, D; Jones, C R; Joram, C; Jost, B; Jurik, N; Kandybei, S; Karacson, M; Kariuki, J M; Karodia, S; Kecke, M; Kelsey, M; Kenzie, M; Ketel, T; Khairullin, E; Khanji, B; Khurewathanakul, C; Kirn, T; Klaver, S; Klimaszewski, K; Koliiev, S; Kolpin, M; Komarov, I; Koopman, R F; Koppenburg, P; Kosmyntseva, A; Kozachuk, A; Kozeiha, M; Kravchuk, L; Kreplin, K; Kreps, M; Krokovny, P; Kruse, F; Krzemien, W; Kucewicz, W; Kucharczyk, M; Kudryavtsev, V; Kuonen, A K; Kurek, K; Kvaratskheliya, T; Lacarrere, D; Lafferty, G; Lai, A; Lanfranchi, G; Langenbruch, C; Latham, T; Lazzeroni, C; Le Gac, R; van Leerdam, J; Leflat, A; Lefrançois, J; Lefèvre, R; Lemaitre, F; Lemos Cid, E; Leroy, O; Lesiak, T; Leverington, B; Li, T; Li, Y; Likhomanenko, T; Lindner, R; Linn, C; Lionetto, F; Liu, X; Loh, D; Longstaff, I; Lopes, J H; Lucchesi, D; Lucio Martinez, M; Luo, H; Lupato, A; Luppi, E; Lupton, O; Lusiani, A; Lyu, X; Machefert, F; Maciuc, F; Maev, O; Maguire, K; Malde, S; Malinin, A; Maltsev, T; Manca, G; Mancinelli, G; Manning, P; Maratas, J; Marchand, J F; Marconi, U; Marin Benito, C; Marinangeli, M; Marino, P; Marks, J; Martellotti, G; Martin, M; Martinelli, M; Martinez Santos, D; Martinez Vidal, F; Martins Tostes, D; Massacrier, L M; Massafferri, A; Matev, R; Mathad, A; Mathe, Z; Matteuzzi, C; Mauri, A; Maurice, E; Maurin, B; Mazurov, A; McCann, M; McNab, A; McNulty, R; Meadows, B; Meier, F; Meissner, M; Melnychuk, D; Merk, M; Merli, A; Michielin, E; Milanes, D A; Minard, M-N; Mitzel, D S; Mogini, A; Molina Rodriguez, J; Monroy, I A; Monteil, S; Morandin, M; Morawski, P; Mordà, A; Morello, M J; Morgunova, O; Moron, J; Morris, A B; Mountain, R; Muheim, F; Mulder, M; Mussini, M; Müller, D; Müller, J; Müller, K; Müller, V; Naik, P; Nakada, T; Nandakumar, R; Nandi, A; Nasteva, I; Needham, M; Neri, N; Neubert, S; Neufeld, N; Neuner, M; Nguyen, T D; Nguyen-Mau, C; Nieswand, S; Niet, R; Nikitin, N; Nikodem, T; Nogay, A; Novoselov, A; O'Hanlon, D P; Oblakowska-Mucha, A; Obraztsov, V; Ogilvy, S; Oldeman, R; Onderwater, C J G; Otalora Goicochea, J M; Otto, A; Owen, P; Oyanguren, A; Pais, P R; Palano, A; Palombo, F; Palutan, M; Papanestis, A; Pappagallo, M; Pappalardo, L L; Parker, W; Parkes, C; Passaleva, G; Pastore, A; Patel, G D; Patel, M; Patrignani, C; Pearce, A; Pellegrino, A; Penso, G; Pepe Altarelli, M; Perazzini, S; Perret, P; Pescatore, L; Petridis, K; Petrolini, A; Petrov, A; Petruzzo, M; Picatoste Olloqui, E; Pietrzyk, B; Pikies, M; Pinci, D; Pistone, A; Piucci, A; Placinta, V; Playfer, S; Plo Casasus, M; Poikela, T; Polci, F; Poluektov, A; Polyakov, I; Polycarpo, E; Pomery, G J; Popov, A; Popov, D; Popovici, B; Poslavskii, S; Potterat, C; Price, E; Price, J D; Prisciandaro, J; Pritchard, A; Prouve, C; Pugatch, V; Puig Navarro, A; Punzi, G; Qian, W; Quagliani, R; Rachwal, B; Rademacker, J H; Rama, M; Ramos Pernas, M; Rangel, M S; Raniuk, I; Ratnikov, F; Raven, G; Redi, F; Reichert, S; Dos Reis, A C; Remon Alepuz, C; Renaudin, V; Ricciardi, S; Richards, S; Rihl, M; Rinnert, K; Rives Molina, V; Robbe, P; Rodrigues, A B; Rodrigues, E; Rodriguez Lopez, J A; Rodriguez Perez, P; Rogozhnikov, A; Roiser, S; Rollings, A; Romanovskiy, V; Romero Vidal, A; Ronayne, J W; Rotondo, M; Rudolph, M S; Ruf, T; Ruiz Valls, P; Saborido Silva, J J; Sadykhov, E; Sagidova, N; Saitta, B; Salustino Guimaraes, V; Sanchez Mayordomo, C; Sanmartin Sedes, B; Santacesaria, R; Santamarina Rios, C; Santimaria, M; Santovetti, E; Sarti, A; Satriano, C; Satta, A; Saunders, D M; Savrina, D; Schael, S; Schellenberg, M; Schiller, M; Schindler, H; Schlupp, M; Schmelling, M; Schmelzer, T; Schmidt, B; Schneider, O; Schopper, A; Schubert, K; Schubiger, M; Schune, M-H; Schwemmer, R; Sciascia, B; Sciubba, A; Semennikov, A; Sergi, A; Serra, N; Serrano, J; Sestini, L; Seyfert, P; Shapkin, M; Shapoval, I; Shcheglov, Y; Shears, T; Shekhtman, L; Shevchenko, V; Siddi, B G; Silva Coutinho, R; Silva de Oliveira, L; Simi, G; Simone, S; Sirendi, M; Skidmore, N; Skwarnicki, T; Smith, E; Smith, I T; Smith, J; Smith, M; Snoek, H; Soares Lavra, L; Sokoloff, M D; Soler, F J P; Souza De Paula, B; Spaan, B; Spradlin, P; Sridharan, S; Stagni, F; Stahl, M; Stahl, S; Stefko, P; Stefkova, S; Steinkamp, O; Stemmle, S; Stenyakin, O; Stevens, H; Stevenson, S; Stoica, S; Stone, S; Storaci, B; Stracka, S; Straticiuc, M; Straumann, U; Sun, L; Sutcliffe, W; Swientek, K; Syropoulos, V; Szczekowski, M; Szumlak, T; T'Jampens, S; Tayduganov, A; Tekampe, T; Tellarini, G; Teubert, F; Thomas, E; van Tilburg, J; Tilley, M J; Tisserand, V; Tobin, M; Tolk, S; Tomassetti, L; Tonelli, D; Topp-Joergensen, S; Toriello, F; Tournefier, E; Tourneur, S; Trabelsi, K; Traill, M; Tran, M T; Tresch, M; Trisovic, A; Tsaregorodtsev, A; Tsopelas, P; Tully, A; Tuning, N; Ukleja, A; Ustyuzhanin, A; Uwer, U; Vacca, C; Vagnoni, V; Valassi, A; Valat, S; Valenti, G; Vazquez Gomez, R; Vazquez Regueiro, P; Vecchi, S; van Veghel, M; Velthuis, J J; Veltri, M; Veneziano, G; Venkateswaran, A; Vernet, M; Vesterinen, M; Viana Barbosa, J V; Viaud, B; Vieira, D; Vieites Diaz, M; Viemann, H; Vilasis-Cardona, X; Vitti, M; Volkov, V; Vollhardt, A; Voneki, B; Vorobyev, A; Vorobyev, V; Voß, C; de Vries, J A; Vázquez Sierra, C; Waldi, R; Wallace, C; Wallace, R; Walsh, J; Wang, J; Ward, D R; Wark, H M; Watson, N K; Websdale, D; Weiden, A; Whitehead, M; Wicht, J; Wilkinson, G; Wilkinson, M; Williams, M; Williams, M P; Williams, M; Williams, T; Wilson, F F; Wimberley, J; Wishahi, J; Wislicki, W; Witek, M; Wormser, G; Wotton, S A; Wraight, K; Wyllie, K; Xie, Y; Xing, Z; Xu, Z; Yang, Z; Yao, Y; Yin, H; Yu, J; Yuan, X; Yushchenko, O; Zarebski, K A; Zavertyaev, M; Zhang, L; Zhang, Y; Zhang, Y; Zhelezov, A; Zheng, Y; Zhu, X; Zhukov, V; Zucchelli, S

    2017-01-01

    A measurement of the phase difference between the short- and long-distance contributions to the [Formula: see text] decay is performed by analysing the dimuon mass distribution. The analysis is based on pp collision data corresponding to an integrated luminosity of 3[Formula: see text] collected by the LHCb experiment in 2011 and 2012. The long-distance contribution to the [Formula: see text] decay is modelled as a sum of relativistic Breit-Wigner amplitudes representing different vector meson resonances decaying to muon pairs, each with their own magnitude and phase. The measured phases of the [Formula: see text] and [Formula: see text] resonances are such that the interference with the short-distance component in dimuon mass regions far from their pole masses is small. In addition, constraints are placed on the Wilson coefficients, [Formula: see text] and [Formula: see text], and the branching fraction of the short-distance component is measured.

  6. Long-distance transport of L-ascorbic acid in potato

    PubMed Central

    Tedone, Luigi; Hancock, Robert D; Alberino, Salvatore; Haupt, Sophie; Viola, Roberto

    2004-01-01

    Background Following on from recent advances in plant AsA biosynthesis there is increasing interest in elucidating the factors contributing to the L-ascorbic acid (AsA) content of edible crops. One main objective is to establish whether in sink organs such as fruits and tubers, AsA is synthesised in situ from imported photoassimilates or synthesised in source tissues and translocated via the phloem. In the current work we test the hypothesis that long-distance transport is involved in AsA accumulation within the potato tuber, the most significant source of AsA in the European diet. Results Using the EDTA exudation technique we confirm the presence of AsA in the phloem of potato plants and demonstrate a correlation between changes in the AsA content of source leaves and that of phloem exudates. Comparison of carboxyflourescein and AgNO3 staining is suggestive of symplastic unloading of AsA in developing tubers. This hypothesis was further supported by the changes in AsA distribution during tuber development which closely resembled those of imported photoassimilates. Manipulation of leaf AsA content by supply of precursors to source leaves resulted in increased AsA content of developing tubers. Conclusion Our data provide strong support to the hypothesis that long-distance transport of AsA occurs in potato. We also show that phloem AsA content and AsA accumulation in sink organs can be directly increased via manipulation of AsA content in the foliage. We are now attempting to establish the quantitative contribution of imported AsA to overall AsA accumulation in developing potato tubers via transgenic approaches. PMID:15377389

  7. Albatross Long-Distance Navigation: Comparing Adults And Juveniles

    NASA Astrophysics Data System (ADS)

    Åkesson, Susanne; Weimerskirch, Henri

    2005-09-01

    Albatrosses are known for their extreme navigation performance enabling them to locate isolated breeding islands after long-distance migrations across open seas. Little is known about the migration of young albatrosses and how they reach the adults' navigation and foraging skills during the period of immaturity lasting several years and spent permanently flying across the open ocean. We tracked by satellite telemetry the dispersal and migration of 13 juvenile wandering albatrosses from the Crozet Islands during their first year at sea. The young albatrosses covered an average distance of 184,000 km during the first year, restricting their dispersal movement to the unproductive and low wind subtropical Indian Ocean and Tasman Sea. The juveniles initiated the migration by an innate phase of rapid dispersal encoded as a fixed flight direction assisted by southerly winds towards north and northeast. Thereafter each individual restricted its movement to a particular zone of the ocean that will possibly be used until they start breeding 7 10 years later and return in contact with breeding adults. This dispersal in young birds corresponds well with movements observed for adult non-breeding wandering albatrosses. The results show clearly an inherited ability to navigate back to already visited areas in young wandering albatrosses. The juvenile dispersal behaviour and migration at sea suggest a genetically based migration program, encoding navigation to a destination area used throughout the life.

  8. Ecological systems as computer networks: Long distance sea dispersal as a communication medium between island plant populations.

    PubMed

    Sanaa, Adnen; Ben Abid, Samir; Boulila, Abdennacer; Messaoud, Chokri; Boussaid, Mohamed; Ben Fadhel, Najeh

    2016-06-01

    Ecological systems are known to exchange genetic material through animal species migration and seed dispersal for plants. Isolated plant populations have developed long distance dispersal as a means of propagation which rely on meteorological such as anemochory and hydrochory for coast, island and river bank dwelling species. Long distance dispersal by water, in particular, in the case of water current bound islands, calls for the analogy with computer networks, where each island and nearby mainland site plays the role of a network node, the water currents play the role of a transmission channel, and water borne seeds as data packets. In this paper we explore this analogy to model long distance dispersal of seeds among island and mainland populations, when traversed with water currents, in order to model and predict their future genetic diversity. The case of Pancratium maritimum L. populations in Tunisia is used as a proof of concept, where their genetic diversity is extrapolated. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  9. Long distance quantum communication with quantum Reed-Solomon codes

    NASA Astrophysics Data System (ADS)

    Muralidharan, Sreraman; Zou, Chang-Ling; Li, Linshu; Jiang, Liang; Jianggroup Team

    We study the construction of quantum Reed Solomon codes from classical Reed Solomon codes and show that they achieve the capacity of quantum erasure channel for multi-level quantum systems. We extend the application of quantum Reed Solomon codes to long distance quantum communication, investigate the local resource overhead needed for the functioning of one-way quantum repeaters with these codes, and numerically identify the parameter regime where these codes perform better than the known quantum polynomial codes and quantum parity codes . Finally, we discuss the implementation of these codes into time-bin photonic states of qubits and qudits respectively, and optimize the performance for one-way quantum repeaters.

  10. Probing the role of long-range interactions in the dynamics of a long-range Kitaev chain

    NASA Astrophysics Data System (ADS)

    Dutta, Anirban; Dutta, Amit

    2017-09-01

    We study the role of long-range interactions (more precisely, the long-range superconducting gap term) on the nonequilibrium dynamics considering a long-range p -wave superconducting chain in which the superconducting term decays with distance between two sites in a power-law fashion characterized by an exponent α . We show that the Kibble-Zurek scaling exponent, dictating the power-law decay of the defect density in the final state reached following a slow (in comparison to the time scale associated with the minimum gap in the spectrum of the Hamiltonian) quenching of the chemical potential μ across a quantum critical point, depends nontrivially on the exponent α as long as α <2 ; on the other hand, for α >2 , we find that the exponent saturates to the corresponding well-known value of 1 /2 expected for the short-range model. Furthermore, studying the dynamical quantum phase transitions manifested in the nonanalyticities in the rate function of the return possibility I (t ) in subsequent temporal evolution following a sudden change in μ , we show the existence of a new region; in this region, we find three instants of cusp singularities in I (t ) associated with a single sector of Fisher zeros. Notably, the width of this region shrinks as α increases and vanishes in the limit α →2 , indicating that this special region is an artifact of the long-range nature of the Hamiltonian.

  11. Athletic identity, compulsive exercise and eating psychopathology in long-distance runners.

    PubMed

    Turton, Robert; Goodwin, Huw; Meyer, Caroline

    2017-08-01

    Having a high athletic identity is thought to increase vulnerability for compulsive exercise and Eating Disorder (ED) psychopathology. This study examined whether there is an association between athletic identity and levels of compulsive exercise and ED psychopathology in long-distance runners. A sample of 501 long-distance runners completed the Athletic Identity Measurement Scale (AIMS), Compulsive Exercise Test (CET) and Eating Disorders Examination Questionnaire (EDEQ). There was a significant positive association between participants' AIMS and total CET scores (moderate effect size; r=0.34 for males and 0.33 for females). BMI did not influence the relationship between AIMS and CET scores in males. However, for females, AIMS scores were positively associated with levels of Weight Control Exercise when covarying for BMI (small to moderate effect size, r=0.22). No significant associations with EDEQ scores were found (negligible to small effect sizes; r=0.06 for males and r=0.14 for females). Following replication, coaches might need to be vigilant to the welfare of endurance runners that have a strong athletic identity, since this could be linked to them exercising compulsively. Future work should examine whether having a strong athletic identity predicts ED psychopathology when this identity is challenged (e.g., due to injury). Copyright © 2017 Elsevier Ltd. All rights reserved.

  12. Diverse spore rains and limited local exchange shape fern genetic diversity in a recently created habitat colonized by long-distance dispersal

    PubMed Central

    De Groot, G. A.; During, H. J.; Ansell, S. W.; Schneider, H.; Bremer, P.; Wubs, E. R. J.; Maas, J. W.; Korpelainen, H.; Erkens, R. H. J.

    2012-01-01

    Background and Aims Populations established by long-distance colonization are expected to show low levels of genetic variation per population, but strong genetic differentiation among populations. Whether isolated populations indeed show this genetic signature of isolation depends on the amount and diversity of diaspores arriving by long-distance dispersal, and time since colonization. For ferns, however, reliable estimates of long-distance dispersal rates remain largely unknown, and previous studies on fern population genetics often sampled older or non-isolated populations. Young populations in recent, disjunct habitats form a useful study system to improve our understanding of the genetic impact of long-distance dispersal. Methods Microsatellite markers were used to analyse the amount and distribution of genetic diversity in young populations of four widespread calcicole ferns (Asplenium scolopendrium, diploid; Asplenium trichomanes subsp. quadrivalens, tetraploid; Polystichum setiferum, diploid; and Polystichum aculeatum, tetraploid), which are rare in The Netherlands but established multiple populations in a forest (the Kuinderbos) on recently reclaimed Dutch polder land following long-distance dispersal. Reference samples from populations throughout Europe were used to assess how much of the existing variation was already present in the Kuinderbos. Key Results A large part of the Dutch and European genetic diversity in all four species was already found in the Kuinderbos. This diversity was strongly partitioned among populations. Most populations showed low genetic variation and high inbreeding coefficients, and were assigned to single, unique gene pools in cluster analyses. Evidence for interpopulational gene flow was low, except for the most abundant species. Conclusions The results show that all four species, diploids as well as polyploids, were capable of frequent long-distance colonization via single-spore establishment. This indicates that even isolated

  13. Resource tracking within and across continents in long-distance bird migrants.

    PubMed

    Thorup, Kasper; Tøttrup, Anders P; Willemoes, Mikkel; Klaassen, Raymond H G; Strandberg, Roine; Vega, Marta Lomas; Dasari, Hari P; Araújo, Miguel B; Wikelski, Martin; Rahbek, Carsten

    2017-01-01

    Migratory birds track seasonal resources across and between continents. We propose a general strategy of tracking the broad seasonal abundance of resources throughout the annual cycle in the longest-distance migrating land birds as an alternative to tracking a certain climatic niche or shorter-term resource surplus occurring, for example, during spring foliation. Whether and how this is possible for complex annual spatiotemporal schedules is not known. New tracking technology enables unprecedented spatial and temporal mapping of long-distance movement of birds. We show that three Palearctic-African species track vegetation greenness throughout their annual cycle, adjusting the timing and direction of migratory movements with seasonal changes in resource availability over Europe and Africa. Common cuckoos maximize the vegetation greenness, whereas red-backed shrikes and thrush nightingales track seasonal surplus in greenness. Our results demonstrate that the longest-distance migrants move between consecutive staging areas even within the wintering region in Africa to match seasonal variation in regional climate. End-of-century climate projections indicate that optimizing greenness would be possible but that vegetation surplus might be more difficult to track in the future.

  14. Resource tracking within and across continents in long-distance bird migrants

    PubMed Central

    Thorup, Kasper; Tøttrup, Anders P.; Willemoes, Mikkel; Klaassen, Raymond H. G.; Strandberg, Roine; Vega, Marta Lomas; Dasari, Hari P.; Araújo, Miguel B.; Wikelski, Martin; Rahbek, Carsten

    2017-01-01

    Migratory birds track seasonal resources across and between continents. We propose a general strategy of tracking the broad seasonal abundance of resources throughout the annual cycle in the longest-distance migrating land birds as an alternative to tracking a certain climatic niche or shorter-term resource surplus occurring, for example, during spring foliation. Whether and how this is possible for complex annual spatiotemporal schedules is not known. New tracking technology enables unprecedented spatial and temporal mapping of long-distance movement of birds. We show that three Palearctic-African species track vegetation greenness throughout their annual cycle, adjusting the timing and direction of migratory movements with seasonal changes in resource availability over Europe and Africa. Common cuckoos maximize the vegetation greenness, whereas red-backed shrikes and thrush nightingales track seasonal surplus in greenness. Our results demonstrate that the longest-distance migrants move between consecutive staging areas even within the wintering region in Africa to match seasonal variation in regional climate. End-of-century climate projections indicate that optimizing greenness would be possible but that vegetation surplus might be more difficult to track in the future. PMID:28070557

  15. Low migratory connectivity is common in long-distance migrant birds.

    PubMed

    Finch, Tom; Butler, Simon J; Franco, Aldina M A; Cresswell, Will

    2017-05-01

    Estimating how much long-distance migrant populations spread out and mix during the non-breeding season (migratory connectivity) is essential for understanding and predicting population dynamics in the face of global change. We quantify variation in population spread and inter-population mixing in long-distance, terrestrial migrant land-bird populations (712 individuals from 98 populations of 45 species, from tagging studies in the Neotropic and Afro-Palearctic flyways). We evaluate the Mantel test as a metric of migratory connectivity, and explore the extent to which variance in population spread can be explained simply by geography. The mean distance between two individuals from the same population during the non-breeding season was 743 km, covering 10-20% of the maximum width of Africa/South America. Individuals from different breeding populations tended to mix during the non-breeding season, although spatial segregation was maintained in species with relatively large non-breeding ranges (and, to a lesser extent, those with low population-level spread). A substantial amount of between-population variation in population spread was predicted simply by geography, with populations using non-breeding zones with limited land availability (e.g. Central America compared to South America) showing lower population spread. The high levels of population spread suggest that deterministic migration tactics are not generally adaptive; this makes sense in the context of the recent evolution of the systems, and the spatial and temporal unpredictability of non-breeding habitat. The conservation implications of generally low connectivity are that the loss (or protection) of any non-breeding site will have a diffuse but widespread effect on many breeding populations. Although low connectivity should engender population resilience to shifts in habitat (e.g. due to climate change), we suggest it may increase susceptibility to habitat loss. We hypothesize that, because a migrant

  16. Interactions between Depression and Facilitation within Neural Networks: Updating the Dual-Process Theory of Plasticity

    PubMed Central

    Prescott, Steven A.

    1998-01-01

    Repetitive stimulation often results in habituation of the elicited response. However, if the stimulus is sufficiently strong, habituation may be preceded by transient sensitization or even replaced by enduring sensitization. In 1970, Groves and Thompson formulated the dual-process theory of plasticity to explain these characteristic behavioral changes on the basis of competition between decremental plasticity (depression) and incremental plasticity (facilitation) occurring within the neural network. Data from both vertebrate and invertebrate systems are reviewed and indicate that the effects of depression and facilitation are not exclusively additive but, rather, that those processes interact in a complex manner. Serial ordering of induction of learning, in which a depressing locus precedes the modulatory system responsible for inducing facilitation, causes the facilitation to wane. The parallel and/or serial expression of depression and waning facilitation within the stimulus–response pathway culminates in the behavioral changes that characterize dual-process learning. A mathematical model is presented to formally express and extend understanding of the interactions between depression and facilitation. PMID:10489261

  17. Guiding of Long-Distance Electric Discharges by Combined Femtosecond and Nanosecond Pulses Emitted by Hybrid KrF Laser System

    DTIC Science & Technology

    2014-01-30

    AFRL-AFOSR-UK-TR-2014-0040 Guiding of long-distance electric discharges by combined femtosecond and nanosecond pulses emitted by...To) 27 September 2010 – 31 December 2013 4. TITLE AND SUBTITLE Guiding of long-distance electric discharges by combined femtosecond and...plasma channels in the atmosphere and laser guiding of high-voltage electric discharges . 15. SUBJECT TERMS EOARD, triggering

  18. CHOLINE TRANSPORTER-LIKE1 is required for sieve plate development to mediate long-distance cell-to-cell communication.

    PubMed

    Dettmer, Jan; Ursache, Robertas; Campilho, Ana; Miyashima, Shunsuke; Belevich, Ilya; O'Regan, Seana; Mullendore, Daniel Leroy; Yadav, Shri Ram; Lanz, Christa; Beverina, Luca; Papagni, Antonio; Schneeberger, Korbinian; Weigel, Detlef; Stierhof, York-Dieter; Moritz, Thomas; Knoblauch, Michael; Jokitalo, Eija; Helariutta, Ykä

    2014-07-10

    Phloem, a plant tissue responsible for long-distance molecular transport, harbours specific junctions, sieve areas, between the conducting cells. To date, little is known about the molecular framework related to the biogenesis of these sieve areas. Here we identify mutations at the CHER1/AtCTL1 locus of Arabidopsis thaliana. The mutations cause several phenotypic abnormalities, including reduced pore density and altered pore structure in the sieve areas associated with impaired phloem function. CHER1 encodes a member of a poorly characterized choline transporter-like protein family in plants and animals. We show that CHER1 facilitates choline transport, localizes to the trans-Golgi network, and during cytokinesis is associated with the phragmoplast. Consistent with its function in the elaboration of the sieve areas, CHER1 has a sustained, polar localization in the forming sieve plates. Our results indicate that the regulation of choline levels is crucial for phloem development and conductivity in plants.

  19. Sporadic nesting reveals long distance colonisation in the philopatric loggerhead sea turtle (Caretta caretta).

    PubMed

    Carreras, Carlos; Pascual, Marta; Tomás, Jesús; Marco, Adolfo; Hochscheid, Sandra; Castillo, Juan José; Gozalbes, Patricia; Parga, Mariluz; Piovano, Susanna; Cardona, Luis

    2018-01-23

    The colonisation of new suitable habitats is crucial for species survival at evolutionary scale under changing environmental conditions. However, colonisation potential may be limited by philopatry that facilitates exploiting successful habitats across generations. We examine the mechanisms of long distance dispersal of the philopatric loggerhead sea turtle (Caretta caretta) by analysing 40 sporadic nesting events in the western Mediterranean. The analysis of a fragment of the mitochondrial DNA and 7 microsatellites of 121 samples from 18 of these nesting events revealed that these nests were colonising events associated with juveniles from distant populations feeding in nearby foraging grounds. Considering the temperature-dependent sex determination of the species, we simulated the effect of the incubation temperature and propagule pressure on a potential colonisation scenario. Our results indicated that colonisation will succeed if warm temperature conditions, already existing in some of the beaches in the area, extend to the whole western Mediterranean. We hypothesize that the sporadic nesting events in developmental foraging grounds may be a mechanism to overcome philopatry limitations thus increasing the dispersal capabilities of the species and the adaptability to changing environments. Sporadic nesting in the western Mediterranean can be viewed as potential new populations in a scenario of rising temperatures.

  20. Would You Do It Again? Relationship Skills Gained in a Long-Distance Relationship

    ERIC Educational Resources Information Center

    Mietzner, Sara; Lin Li-Wen

    2005-01-01

    This study examined if experienced long-distance relationship (LDR) participants would be willing to be involved in a LDR again. In addition, although positive and negative outcomes have been reported in LDRs research, very little research investigated relationship skills gained during a LDR. Students in a Midwestern university completed…

  1. DISTANCES TO DARK CLOUDS: COMPARING EXTINCTION DISTANCES TO MASER PARALLAX DISTANCES

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Foster, Jonathan B.; Jackson, James M.; Stead, Joseph J.

    We test two different methods of using near-infrared extinction to estimate distances to dark clouds in the first quadrant of the Galaxy using large near-infrared (Two Micron All Sky Survey and UKIRT Infrared Deep Sky Survey) surveys. Very long baseline interferometry parallax measurements of masers around massive young stars provide the most direct and bias-free measurement of the distance to these dark clouds. We compare the extinction distance estimates to these maser parallax distances. We also compare these distances to kinematic distances, including recent re-calibrations of the Galactic rotation curve. The extinction distance methods agree with the maser parallax distancesmore » (within the errors) between 66% and 100% of the time (depending on method and input survey) and between 85% and 100% of the time outside of the crowded Galactic center. Although the sample size is small, extinction distance methods reproduce maser parallax distances better than kinematic distances; furthermore, extinction distance methods do not suffer from the kinematic distance ambiguity. This validation gives us confidence that these extinction methods may be extended to additional dark clouds where maser parallaxes are not available.« less

  2. Connecting long distance: semantic distance in analogical reasoning modulates frontopolar cortex activity.

    PubMed

    Green, Adam E; Kraemer, David J M; Fugelsang, Jonathan A; Gray, Jeremy R; Dunbar, Kevin N

    2010-01-01

    Solving problems often requires seeing new connections between concepts or events that seemed unrelated at first. Innovative solutions of this kind depend on analogical reasoning, a relational reasoning process that involves mapping similarities between concepts. Brain-based evidence has implicated the frontal pole of the brain as important for analogical mapping. Separately, cognitive research has identified semantic distance as a key characteristic of the kind of analogical mapping that can support innovation (i.e., identifying similarities across greater semantic distance reveals connections that support more innovative solutions and models). However, the neural substrates of semantically distant analogical mapping are not well understood. Here, we used functional magnetic resonance imaging (fMRI) to measure brain activity during an analogical reasoning task, in which we parametrically varied the semantic distance between the items in the analogies. Semantic distance was derived quantitatively from latent semantic analysis. Across 23 participants, activity in an a priori region of interest (ROI) in left frontopolar cortex covaried parametrically with increasing semantic distance, even after removing effects of task difficulty. This ROI was centered on a functional peak that we previously associated with analogical mapping. To our knowledge, these data represent a first empirical characterization of how the brain mediates semantically distant analogical mapping.

  3. Correcting Students' Misconceptions about Automobile Braking Distances and Video Analysis Using Interactive Program Tracker

    ERIC Educational Resources Information Center

    Hockicko, Peter; Trpišová, Beáta; Ondruš, Ján

    2014-01-01

    The present paper informs about an analysis of students' conceptions about car braking distances and also presents one of the novel methods of learning: an interactive computer program Tracker that we used to analyse the process of braking of a car. The analysis of the students' conceptions about car braking distances consisted in…

  4. Long-distance continuous-variable quantum key distribution using non-Gaussian state-discrimination detection

    NASA Astrophysics Data System (ADS)

    Liao, Qin; Guo, Ying; Huang, Duan; Huang, Peng; Zeng, Guihua

    2018-02-01

    We propose a long-distance continuous-variable quantum key distribution (CVQKD) with a four-state protocol using non-Gaussian state-discrimination detection. A photon subtraction operation, which is deployed at the transmitter, is used for splitting the signal required for generating the non-Gaussian operation to lengthen the maximum transmission distance of the CVQKD. Whereby an improved state-discrimination detector, which can be deemed as an optimized quantum measurement that allows the discrimination of nonorthogonal coherent states beating the standard quantum limit, is applied at the receiver to codetermine the measurement result with the conventional coherent detector. By tactfully exploiting the multiplexing technique, the resulting signals can be simultaneously transmitted through an untrusted quantum channel, and subsequently sent to the state-discrimination detector and coherent detector, respectively. Security analysis shows that the proposed scheme can lengthen the maximum transmission distance up to hundreds of kilometers. Furthermore, by taking the finite-size effect and composable security into account we obtain the tightest bound of the secure distance, which is more practical than that obtained in the asymptotic limit.

  5. Connecticut's Evolving Interactive Distance Learning Network in the Cable and Telecommunications Industries.

    ERIC Educational Resources Information Center

    Pietras, Jesse John

    This paper describes the state of interactive distance learning in Connecticut, particularly the current and future provision of these services by the telecommunications and cable television industries. The overview examines questions of where obligation and responsibility lie (with schools, local exchange companies, cable franchises, etc.) in…

  6. Quantum-limited heat conduction over macroscopic distances

    NASA Astrophysics Data System (ADS)

    Partanen, Matti; Tan, Kuan Yen; Govenius, Joonas; Lake, Russell E.; Mäkelä, Miika K.; Tanttu, Tuomo; Möttönen, Mikko

    2016-05-01

    The emerging quantum technological apparatuses, such as the quantum computer, call for extreme performance in thermal engineering. Cold distant heat sinks are needed for the quantized electric degrees of freedom owing to the increasing packaging density and heat dissipation. Importantly, quantum mechanics sets a fundamental upper limit for the flow of information and heat, which is quantified by the quantum of thermal conductance. However, the short distance between the heat-exchanging bodies in the previous experiments hinders their applicability in quantum technology. Here, we present experimental observations of quantum-limited heat conduction over macroscopic distances extending to a metre. We achieved this improvement of four orders of magnitude in the distance by utilizing microwave photons travelling in superconducting transmission lines. Thus, it seems that quantum-limited heat conduction has no fundamental distance cutoff. This work establishes the integration of normal-metal components into the framework of circuit quantum electrodynamics, which provides a basis for the superconducting quantum computer. Especially, our results facilitate remote cooling of nanoelectronic devices using faraway in situ-tunable heat sinks. Furthermore, quantum-limited heat conduction is important in contemporary thermodynamics. Here, the long distance may lead to ultimately efficient mesoscopic heat engines with promising practical applications.

  7. Index mismatch aberration correction over long working distances using spatial light modulation.

    PubMed

    Gjonaj, Bergin; Johnson, Patrick; Bonn, Mischa; Domke, Katrin F

    2012-11-20

    For many microscopy applications, millimeters-long free working distances (LWD) are required. However, the high resolution and contrast of LWD objectives operated in air are lost when introducing glass and/or liquid with the sample. We propose to use spatial light modulation to correct for such beam aberrations caused by refractive index mismatches. Focusing a monochromatic laser beam with a 10 mm working distance air objective (50×, 0.5 NA) through air, glass, and water, we manage to restore a sharp, intense focus (FWHM<2λ) by adaptive beam phase shaping. Our approach offers a practical and cost-effective route to high resolution and contrast microscopy using LWD air objectives, extending their usage beyond applications in air.

  8. Working Memory in the Processing of Long-Distance Dependencies: Interference and Filler Maintenance

    ERIC Educational Resources Information Center

    Ness, Tal; Meltzer-Asscher, Aya

    2017-01-01

    During the temporal delay between the filler and gap sites in long-distance dependencies, the "active filler" strategy can be implemented in two ways: the filler phrase can be actively maintained in working memory ("maintenance account"), or it can be retrieved only when the parser posits a gap ("retrieval account").…

  9. Trade-off between competition and facilitation defines gap colonization in mountains.

    PubMed

    Lembrechts, Jonas J; Milbau, Ann; Nijs, Ivan

    2015-11-10

    Recent experimental observations show that gap colonization in small-stature (e.g. grassland and dwarf shrubs) vegetation strongly depends on the abiotic conditions within them. At the same time, within-gap variation in biotic interactions such as competition and facilitation, caused by distance to the gap edge, would affect colonizer performance, but a theoretical framework to explore such patterns is missing. Here, we model how competition, facilitation and environmental conditions together determine the small-scale patterns of gap colonization along a cold gradient in mountains, by simulating colonizer survival in gaps of various sizes. Our model adds another dimension to the known effects of biotic interactions along a stress gradient by focussing on the trade-off between competition and facilitation in the within-gap environment. We show that this trade-off defines a peak in colonizer survival at a specific distance from the gap edge, which progressively shifts closer to the edge as the environment gets colder, ultimately leaving a large fraction of gaps unsuitable for colonization in facilitation-dominated systems. This is reinforced when vegetation size and temperature amelioration are manipulated simultaneously with temperature in order to simulate an elevational gradient more realistically. Interestingly, all other conditions being equal, the magnitude of the realized survival peak was always lower in large than in small gaps, making large gaps harder to colonize. The model is relevant to predict effects of non-native plant invasions and climate warming on colonization processes in mountains. Published by Oxford University Press on behalf of the Annals of Botany Company.

  10. Time to cash in on positive interactions for coral restoration

    PubMed Central

    Silliman, Brian R.

    2017-01-01

    Coral reefs are among the most biodiverse and productive ecosystems on Earth, and provide critical ecosystem services such as protein provisioning, coastal protection, and tourism revenue. Despite these benefits, coral reefs have been declining precipitously across the globe due to human impacts and climate change. Recent efforts to combat these declines are increasingly turning to restoration to help reseed corals and speed-up recovery processes. Coastal restoration theory and practice has historically favored transplanting designs that reduce potentially harmful negative species interactions, such as competition between transplants. However, recent research in salt marsh ecosystems has shown that shifting this theory to strategically incorporate positive interactions significantly enhances restoration yield with little additional cost or investment. Although some coral restoration efforts plant corals in protected areas in order to benefit from the facilitative effects of herbivores that reduce competitive macroalgae, little systematic effort has been made in coral restoration to identify the entire suite of positive interactions that could promote population enhancement efforts. Here, we highlight key positive species interactions that managers and restoration practitioners should utilize to facilitate the restoration of corals, including (i) trophic facilitation, (ii) mutualisms, (iii) long-distance facilitation, (iv) positive density-dependence, (v) positive legacy effects, and (vi) synergisms between biodiversity and ecosystem function. As live coral cover continues to decline and resources are limited to restore coral populations, innovative solutions that increase efficiency of restoration efforts will be critical to conserving and maintaining healthy coral reef ecosystems and the human communities that rely on them. PMID:28652942

  11. EEG correlates of social interaction at distance

    PubMed Central

    Giroldini, William; Pederzoli, Luciano; Bilucaglia, Marco; Caini, Patrizio; Ferrini, Alessandro; Melloni, Simone; Prati, Elena; Tressoldi, Patrizio

    2016-01-01

    This study investigated EEG correlates of social interaction at distance between twenty-five pairs of participants who were not connected by any traditional channels of communication. Each session involved the application of 128 stimulations separated by intervals of random duration ranging from 4 to 6 seconds. One of the pair received a one-second stimulation from a light signal produced by an arrangement of red LEDs, and a simultaneous 500 Hz sinusoidal audio signal of the same length. The other member of the pair sat in an isolated sound-proof room, such that any sensory interaction between the pair was impossible. An analysis of the Event-Related Potentials associated with sensory stimulation using traditional averaging methods showed a distinct peak at approximately 300 ms, but only in the EEG activity of subjects who were directly stimulated. However, when a new algorithm was applied to the EEG activity based on the correlation between signals from all active electrodes, a weak but robust response was also detected in the EEG activity of the passive member of the pair, particularly within 9 – 10 Hz in the Alpha range. Using the Bootstrap method and the Monte Carlo emulation, this signal was found to be statistically significant. PMID:26966513

  12. Characteristics of Organic-Metal Interaction: A Perspective from Bonding Distance to Orbital Delocalization

    NASA Astrophysics Data System (ADS)

    Kera, Satoshi; Hosokai, Takuya; Duhm, Steffen

    2018-06-01

    Understanding the mechanisms of energy-level alignment and charge transfer at the interface is one of the key issues in realizing organic electronics. However, the relation between the interface structure and the electronic structure is still not resolved in sufficient detail. An important character of materials used in organic electronics is the electronic localization of organic molecules at interfaces. To elucidate the impact of the molecular orbital distribution on the electronic structure, detailed structural information is required, particularly the vertical bonding distance at the interface, which is a signature of the interaction strength. We describe the recent progress in experimental studies on the impact of the molecule-metal interaction on the electronic structure of organic-metal interfaces by using various photoelectron spectroscopies, and review the results, focusing on the X-ray standing wave technique, to demonstrate the evaluation of the vertical bonding distance.

  13. Influence of very-long-distance earthquakes on the ionosphere?

    NASA Astrophysics Data System (ADS)

    Liperovskaya, E. V.; Meister, C.-V.; Biagi, P.-F.; Liperovsky, V. A.; Rodkin, M. V.

    2009-04-01

    In the present work, variations of the critical frequency foF2 obtained every hour by the ionospheric sounding station Tashkent (41.3oN, 69.6oE) in the years 1964-1996 are considered. Mean values of data found at day-time between 11 LT and 16 LT are investigated. Disturbances of foF2 related to earthquakes are studied on the background of seasonal, geomagnetic, 11-years and 27-days solar variations. Normalized values F are used in the analysis, which are obtained excluding the seasonal run by subtracting the mean value of foF2 during the time interval of 14 days, from 7 days before the earthquake until seven days after the event, and dividing the result on its standard deviation. Days with high solar (Wolf number > 200) and geomagnetic (ΣKp > 25) disturbances are excluded from the analysis. Using the method of superposition of epoches it is concluded, that at the day of the earthquake the foF2 value decreases a) in case of earthquakes with magnitudes M > 6.5 at any place on the Earth, if the depth h of the epicentre satisfies h < 200 km, b) in connection with earthquakes with magnitudes 6.5 > M > 6.0 occurring in the Middle Asia region, if h < 70 km is satisfied, and c) in connection with earthquakes with magnitudes 6.0 > M > 5.5 appearing at a distance from Tashkent smaller than 1000 km if one has h < 70 km. In all investigated cases the reliability of the effect is larger than 95 %. The ratio of the number of earthquakes with a decrease of the foF2-value to the number of earthquakes where foF2 grows is about 2. The decrease of the foF2-value is also obtained some hours before and some hours - a day - after the event. Thus, one may assume that before an earthquake happening at a long distance, in the vicinity of the sounding station seismo-gravity waves with periods between half an hour and a few hours propagate through the earth's core. After long-distance earthquakes, seismic waves propagate in the vicinity of the sounding station. But in both cases, the

  14. Comparison of sequence of trunk and arm motions between short and long official distance groups in javelin throwing.

    PubMed

    Liu, Hui; Leigh, Steve; Yu, Bing

    2014-03-01

    The purpose of this study was to determine the effects of sequences of the trunk and arm angular motions on the performance of javelin throwing. In this study, 32 male and 30 female elite javelin throwers participated and were separated into a short official distance group or a long official distance group in each gender. Three-dimensional coordinates of 21 body landmarks and 3 marks on the javelin in the best trial were collected for each subject. Joint center linear velocities and selected trunk and arm segment and joint angles and angular velocities were calculated. The times of the initiations of the selected segment and joint angular motions and maximum angular velocities were determined. The sequences of the initiations of the selected segment and joint angular motions and maximum angular velocities were compared between short and long official distance groups and between genders. The results demonstrated that short and long official distance groups employed similar sequences of the trunk and arm motions. Male and female javelin throwers employed different sequences of the trunk and arm motions. The sequences of the trunk and arm motions were different from those of the maximal joint center linear velocities.

  15. Epidemiology of road traffic crashes among long distance drivers in Ibadan, Nigeria.

    PubMed

    Adejugbagbe, Adewale Moses; Fatiregun, Akinola Ayoola; Rukewe, Ambrose; Alonge, Temitope

    2015-06-01

    Road Traffic Crashes (RTCs) are major causes of morbidity and mortality in Nigeria. Few studies in Ibadan have focused on the distribution and determinants of RTC among long distance drivers. To describe the distribution of crashes by place, times of occurrence, characteristics of persons involved and identify associated factors. A cross-sectional study was carried out among consenting long distance drivers within selected parks in Ibadan. Respondents (592) were males, with median age of 42.0 years (range 22.0-73.0 years). Secondary education was the highest level of education attained by 38.0%. About 34.0% reported current use of alcohol. The life-time prevalence of crashes was 35.3% (95% CI= 31.5-39.2%) and 15.9% (95% CI=13.1-19.0%) reported having had at least one episode of crash in the last one year preceding the study. The crash occurred mainly on narrow roads [32/94 (34.0%,)] and bad portions of tarred roads [35/94 (37.2%,)] with peak of occurrence on Saturdays 18/94 (19.1%,). Significantly higher proportions of drivers aged ≤39years (23.4%) versus >39years (11.7%), those with no education (29.9%) versus the educated (13.8%) and those who reported alcohol use (21.9%) versus non users (12.8%) were involved in crashes in the year preceding the study. Significant predictor of the last episode of crashes in the last one year were age (OR=2.2, 95% CI=1.4-3.5), education (OR=2.7, 95% CI=1.5-4.6) and alcohol use (OR=1.8, 95% CI=1.2-3.0). Road traffic crashes occurred commonly on bad roads, in the afternoon and during weekends, among young and uneducated long-distance drivers studied. Reconstruction of bad roads and implementation of road safety education programmes aimed at discouraging the use of alcohol and targeting the identified groups at risk are recommended.

  16. Correcting Distance Estimates by Interacting With Immersive Virtual Environments: Effects of Task and Available Sensory Information

    ERIC Educational Resources Information Center

    Waller, David; Richardson, Adam R.

    2008-01-01

    The tendency to underestimate egocentric distances in immersive virtual environments (VEs) is not well understood. However, previous research (A. R. Richardson & D. Waller, 2007) has demonstrated that a brief period of interaction with the VE prior to making distance judgments can effectively eliminate subsequent underestimation. Here the authors…

  17. Plantar pressure changes after long-distance walking.

    PubMed

    Stolwijk, Niki M; Duysens, Jacques; Louwerens, Jan Willem K; Keijsers, Noël L W

    2010-12-01

    The popularity of long-distance walking (LDW) has increased in the last decades. However, the effects of LDW on plantar pressure distribution and foot complaints, in particular, after several days of walking, have not been studied. We obtained the plantar pressure data of 62 subjects who had no history of foot complaints and who walked a total distance of 199.8 km for men (n = 30) and 161.5 km for women (n = 32) during four consecutive days. Plantar pressure was measured each day after the finish (posttests I–IV) and compared with the baseline plantar pressure data, which was obtained 1 or 2 d before the march (pretest). Mean, peak, and pressure–time integral per pixel as well as the center of pressure (COP) trajectory of each foot per measurement day were calculated using the normalization method of Keijsers et al. A paired t-test with an adjusted P value was used to detect significant differences between pretest and posttest. Short-term adjustment to LDW resulted in a significant decreased loading on the toes accompanied with an increased loading on the metatarsal head III–V (P < 0.001). At all stages, particularly at later stages, there was significantly more heel loading (P < 0.001). Furthermore, the COP significantly displaced in the posterior direction but not in the mediolateral direction after marching. Contact time increased slightly from 638.5 +/- 24.2 to 675.4 +/- 22.5 ms (P < 0.001). The increased heel loading and decreased function of the toes found after marching indicate a change of walking pattern with less roll-off. It is argued that these changes reflect the effect of fatigue of the lower leg muscles and to avoid loading of the most vulnerable parts of the foot.

  18. Peculiarities of the detection and identification of substance at long distance

    NASA Astrophysics Data System (ADS)

    Trofimov, Vyacheslav A.; Varentsova, Svetlana A.; Trofimov, Vladislav V.; Tikhomirov, Vasily V.

    2014-05-01

    Nowadays, the detection and identification of dangerous substances at long distance (several meters, for example) by using of THz pulse reflected from the object is an important problem. In this report we demonstrate possibility of THz signal measuring reflected from investigated object that is placed before a flat metallic mirror. A distance between the flat mirror and the parabolic mirror this mirror is equal to 3.5 meters. Therefore, at present time our measurements contain features of both transmission and reflection modes. The reflecting mirror is used because of weak average power of used femtosecond laser. Measurements were provided at room temperature and humidity about 60%. The aim of investigation was the detection of a substance in real condition. Chocolate and Cookies were used as samples for identification. We also discuss modified correlation criteria for the detection and identification of various substances using pulsed THz signal in the transmission and reflection mode at short distances of about 30-40 cm. These criteria are integral criteria in time and they are based on the SDA method. Proposed algorithms show both high probability of the substance identification and a reliability of realization in practice. We compare P-spectrum and SDA- methods in the paper and show that P-spectrum method is a partial case of SDAmethod.

  19. Using Interactive "Shiny" Applications to Facilitate Research-Informed Learning and Teaching

    ERIC Educational Resources Information Center

    Fawcett, Lee

    2018-01-01

    In this article we discuss our attempt to incorporate research-informed learning and teaching activities into a final year undergraduate Statistics course. We make use of the Shiny web-based application framework for R to develop "Shiny apps" designed to help facilitate student interaction with methods from recently published papers in…

  20. Enhancing practice improvement by facilitating practitioner interactivity: new roles for providers of continuing medical education.

    PubMed

    Parboosingh, I John; Reed, Virginia A; Caldwell Palmer, James; Bernstein, Henry H

    2011-01-01

    Research into networking and interactivity among practitioners is providing new information that has the potential to enhance the effectiveness of practice improvement initiatives. This commentary reviews the evidence that practitioner interactivity can facilitate emergent learning and behavior change that lead to practice improvements. Insights from learning theories provide a framework for understanding emergent learning as the product of interactions between individuals in trusted relationships, such as occurs in communities of practice. This framework helps explain why some groups respond more favorably to improvement initiatives than others. Failure to take advantage of practitioner interactivity may explain in part the disappointingly low mean rates of practice improvement reported in studies of the effectiveness of practice improvement projects. Examples of improvement models in primary care settings that explicitly use relationship building and facilitation techniques to enhance practitioner interactivity are provided. Ingredients of a curriculum to teach relationship building in communities of practice and facilitation skills to enhance learning in small group education sessions are explored. Sufficient evidence exists to support the roles of relationships and interactivity in practice improvement initiatives such that we recommend the development of training programs to teach these skills to CME providers. Copyright © 2011 The Alliance for Continuing Medical Education, the Society for Academic Continuing Medical Education, and the Council on CME, Association for Hospital Medical Education.

  1. The fate of organic micropollutants during long-term/long-distance river bank filtration.

    PubMed

    Hamann, Enrico; Stuyfzand, Pieter J; Greskowiak, Janek; Timmer, Harrie; Massmann, Gudrun

    2016-03-01

    The fate of organic micropollutants during long-term/long-distance river bank filtration (RBF) at a temporal scale of several years was investigated along a row of monitoring wells perpendicular to the Lek River (the Netherlands). Out of 247 compounds, which were irregularly analyzed in the period 1999-2013, only 15 were detected in both the river and river bank observation wells. Out of these, 10 compounds (1,4-dioxan, 1,5-naphthalene disulfonate (1,5-NDS), 2-amino-1,5-NDS, 3-amino-1,5-NDS, AOX, carbamazepine, EDTA, MTBE, toluene and triphenylphosphine oxide) showed fully persistent behavior (showing no concentration decrease at all), even after 3.6 years transit time. The remaining 5 compounds (1,3,5-naphthalene trisulfonate (1,3,5-NTS), 1,3,6-NTS, diglyme, iopamidol, triglyme) were partially removed. Their reactive transport parameters (removal rate constants/half-lives, retardation coefficients) were inferred from numerical modeling. In addition, maximum half-lives for 14 of the fully removed compounds, for which the data availability was sufficient to deduce 100% removal during sub-surface passage, were approximated based on travel times to the nearest well. The study is one of very few reporting on the long-term field-scale behavior of organic micropollutants. It highlights the efficiency of RBF for water quality improvement as a pre-treatment step for drinking water production. However, it also shows the very persistent behavior of various compounds in groundwater. Copyright © 2015 Elsevier B.V. All rights reserved.

  2. Postsynaptic Regulation of Long-Term Facilitation in Aplysia

    PubMed Central

    Cai, Diancai; Chen, Shanping; Glanzman, David L.

    2009-01-01

    Summary Repeated exposure to serotonin (5-HT), an endogenous neurotransmitter that mediates behavioral sensitization in Aplysia [1–3], induces long-term facilitation (LTF) of the Aplysia sensorimotor synapse [4]. LTF, a prominent form of invertebrate synaptic plasticity, is believed to play a major role in long-term learning in Aplysia [5]. Until now, LTF has been thought to be due predominantly to cellular processes activated by 5-HT within the presynaptic sensory neuron [6]. Recent work indicates that LTF depends on the increased expression and release of a sensory neuron-specific neuropeptide, sensorin [7]. Sensorin released during LTF appears to bind to autoreceptors on the sensory neuron, thereby activating critical presynaptic signals, including mitogen-activated protein kinase (MAPK) [8, 9]. Here, we show that LTF depends on elevated postsynaptic Ca2+ and postsynaptic protein synthesis. Furthermore, we find that the increased expression of presynaptic sensorin due to 5-HT stimulation requires elevation of postsynaptic intracellular Ca2+. Our results represent perhaps the strongest evidence to date that the increased expression of a specific presynaptic neuropeptide during LTF is regulated by retrograde signals. PMID:18571411

  3. Extensive long-distance pollen dispersal and highly outcrossed mating in historically small and disjunct populations of Acacia woodmaniorum (Fabaceae), a rare banded iron formation endemic.

    PubMed

    Millar, Melissa A; Coates, David J; Byrne, Margaret

    2014-10-01

    Understanding patterns of pollen dispersal and variation in mating systems provides insights into the evolutionary potential of plant species and how historically rare species with small disjunct populations persist over long time frames. This study aims to quantify the role of pollen dispersal and the mating system in maintaining contemporary levels of connectivity and facilitating persistence of small populations of the historically rare Acacia woodmaniorum. Progeny arrays of A. woodmaniorum were genotyped with nine polymorphic microsatellite markers. A low number of fathers contributed to seed within single pods; therefore, sampling to remove bias of correlated paternity was implemented for further analysis. Pollen immigration and mating system parameters were then assessed in eight populations of varying size and degree of isolation. Pollen immigration into small disjunct populations was extensive (mean minimum estimate 40 % and mean maximum estimate 57 % of progeny) and dispersal occurred over large distances (≤1870m). Pollen immigration resulted in large effective population sizes and was sufficient to ensure adaptive and inbreeding connectivity in small disjunct populations. High outcrossing (mean tm = 0·975) and a lack of apparent inbreeding suggested that a self-incompatibility mechanism is operating. Population parameters, including size and degree of geographic disjunction, were not useful predictors of pollen dispersal or components of the mating system. Extensive long-distance pollen dispersal and a highly outcrossed mating system are likely to play a key role in maintaining genetic diversity and limiting negative genetic effects of inbreeding and drift in small disjunct populations of A. woodmaniorum. It is proposed that maintenance of genetic connectivity through habitat and pollinator conservation will be a key factor in the persistence of this and other historically rare species with similar extensive long-distance pollen dispersal and highly

  4. Direct solution of the H(1s)-H + long-range interaction problem in momentum space

    NASA Astrophysics Data System (ADS)

    Koga, Toshikatsu

    1985-02-01

    Perturbation equations for the H(1s)-H+ long-range interaction are solved directly in momentum space up to the fourth order with respect to the reciprocal of the internuclear distance. As in the hydrogen atom problem, the Fock transformation is used which projects the momentum vector of an electron from the three-dimensional hyperplane onto the four-dimensional hypersphere. Solutions are given as linear combinations of several four-dimensional spherical harmonics. The present results add an example to the momentum-space solution of the nonspherical potential problem.

  5. Temperature-Dependent Wsm1 and Wsm2 Gene-Specific Blockage of Viral Long-Distance Transport Provides Resistance to Wheat streak mosaic virus and Triticum mosaic virus in Wheat.

    PubMed

    Tatineni, Satyanarayana; Wosula, Everlyne N; Bartels, Melissa; Hein, Gary L; Graybosch, Robert A

    2016-09-01

    Wheat streak mosaic virus (WSMV) and Triticum mosaic virus (TriMV) are economically important viral pathogens of wheat. Wheat cvs. Mace, carrying the Wsm1 gene, is resistant to WSMV and TriMV, and Snowmass, with Wsm2, is resistant to WSMV. Viral resistance in both cultivars is temperature sensitive and is effective at 18°C or below but not at higher temperatures. The underlying mechanisms of viral resistance of Wsm1 and Wsm2, nonallelic single dominant genes, are not known. In this study, we found that fluorescent protein-tagged WSMV and TriMV elicited foci that were approximately similar in number and size at 18 and 24°C, on inoculated leaves of resistant and susceptible wheat cultivars. These data suggest that resistant wheat cultivars at 18°C facilitated efficient cell-to-cell movement. Additionally, WSMV and TriMV efficiently replicated in inoculated leaves of resistant wheat cultivars at 18°C but failed to establish systemic infection, suggesting that Wsm1- and Wsm2-mediated resistance debilitated viral long-distance transport. Furthermore, we found that neither virus was able to enter the leaf sheaths of inoculated leaves or crowns of resistant wheat cultivars at 18°C but both were able to do so at 24°C. Thus, wheat cvs. Mace and Snowmass provide resistance at the long-distance movement stage by specifically blocking virus entry into the vasculature. Taken together, these data suggest that both Wsm1 and Wsm2 genes similarly confer virus resistance by temperature-dependent impairment of viral long-distance movement.

  6. T-Cell Receptors Binding Orientation over Peptide/MHC Class I Is Driven by Long-Range Interactions

    PubMed Central

    Ferber, Mathias; Zoete, Vincent; Michielin, Olivier

    2012-01-01

    Crystallographic data about T-Cell Receptor – peptide – major histocompatibility complex class I (TCRpMHC) interaction have revealed extremely diverse TCR binding modes triggering antigen recognition. Understanding the molecular basis that governs TCR orientation over pMHC is still a considerable challenge. We present a simplified rigid approach applied on all non-redundant TCRpMHC crystal structures available. The CHARMM force field in combination with the FACTS implicit solvation model is used to study the role of long-distance interactions between the TCR and pMHC. We demonstrate that the sum of the coulomb interactions and the electrostatic solvation energies is sufficient to identify two orientations corresponding to energetic minima at 0° and 180° from the native orientation. Interestingly, these results are shown to be robust upon small structural variations of the TCR such as changes induced by Molecular Dynamics simulations, suggesting that shape complementarity is not required to obtain a reliable signal. Accurate energy minima are also identified by confronting unbound TCR crystal structures to pMHC. Furthermore, we decompose the electrostatic energy into residue contributions to estimate their role in the overall orientation. Results show that most of the driving force leading to the formation of the complex is defined by CDR1,2/MHC interactions. This long-distance contribution appears to be independent from the binding process itself, since it is reliably identified without considering neither short-range energy terms nor CDR induced fit upon binding. Ultimately, we present an attempt to predict the TCR/pMHC binding mode for a TCR structure obtained by homology modeling. The simplicity of the approach and the absence of any fitted parameters make it also easily applicable to other types of macromolecular protein complexes. PMID:23251658

  7. T-cell receptors binding orientation over peptide/MHC class I is driven by long-range interactions.

    PubMed

    Ferber, Mathias; Zoete, Vincent; Michielin, Olivier

    2012-01-01

    Crystallographic data about T-Cell Receptor - peptide - major histocompatibility complex class I (TCRpMHC) interaction have revealed extremely diverse TCR binding modes triggering antigen recognition. Understanding the molecular basis that governs TCR orientation over pMHC is still a considerable challenge. We present a simplified rigid approach applied on all non-redundant TCRpMHC crystal structures available. The CHARMM force field in combination with the FACTS implicit solvation model is used to study the role of long-distance interactions between the TCR and pMHC. We demonstrate that the sum of the coulomb interactions and the electrostatic solvation energies is sufficient to identify two orientations corresponding to energetic minima at 0° and 180° from the native orientation. Interestingly, these results are shown to be robust upon small structural variations of the TCR such as changes induced by Molecular Dynamics simulations, suggesting that shape complementarity is not required to obtain a reliable signal. Accurate energy minima are also identified by confronting unbound TCR crystal structures to pMHC. Furthermore, we decompose the electrostatic energy into residue contributions to estimate their role in the overall orientation. Results show that most of the driving force leading to the formation of the complex is defined by CDR1,2/MHC interactions. This long-distance contribution appears to be independent from the binding process itself, since it is reliably identified without considering neither short-range energy terms nor CDR induced fit upon binding. Ultimately, we present an attempt to predict the TCR/pMHC binding mode for a TCR structure obtained by homology modeling. The simplicity of the approach and the absence of any fitted parameters make it also easily applicable to other types of macromolecular protein complexes.

  8. Quantum spin dynamics with pairwise-tunable, long-range interactions

    PubMed Central

    Hung, C.-L.; González-Tudela, Alejandro; Cirac, J. Ignacio; Kimble, H. J.

    2016-01-01

    We present a platform for the simulation of quantum magnetism with full control of interactions between pairs of spins at arbitrary distances in 1D and 2D lattices. In our scheme, two internal atomic states represent a pseudospin for atoms trapped within a photonic crystal waveguide (PCW). With the atomic transition frequency aligned inside a band gap of the PCW, virtual photons mediate coherent spin–spin interactions between lattice sites. To obtain full control of interaction coefficients at arbitrary atom–atom separations, ground-state energy shifts are introduced as a function of distance across the PCW. In conjunction with auxiliary pump fields, spin-exchange versus atom–atom separation can be engineered with arbitrary magnitude and phase, and arranged to introduce nontrivial Berry phases in the spin lattice, thus opening new avenues for realizing topological spin models. We illustrate the broad applicability of our scheme by explicit construction for several well-known spin models. PMID:27496329

  9. Long-distance plant dispersal to North Atlantic islands: colonization routes and founder effect

    PubMed Central

    Alsos, Inger Greve; Ehrich, Dorothee; Eidesen, Pernille Bronken; Solstad, Heidi; Westergaard, Kristine Bakke; Schönswetter, Peter; Tribsch, Andreas; Birkeland, Siri; Elven, Reidar; Brochmann, Christian

    2015-01-01

    Long-distance dispersal (LDD) processes influence the founder effect on islands. We use genetic data for 25 Atlantic species and similarities among regional floras to analyse colonization, and test whether the genetic founder effect on five islands is associated with dispersal distance, island size and species traits. Most species colonized postglacially via multiple dispersal events from several source regions situated 280 to >3000 km away, and often not from the closest ones. A strong founder effect was observed for insect-pollinated mixed maters, and it increased with dispersal distance and decreased with island size in accordance with the theory of island biogeography. Only a minor founder effect was observed for wind-pollinated outcrossing species. Colonization patterns were largely congruent, indicating that despite the importance of stochasticity, LDD is mainly determined by common factors, probably dispersal vectors. Our findings caution against a priori assuming a single, close source region in biogeographic analyses. PMID:25876627

  10. Long-distance plant dispersal to North Atlantic islands: colonization routes and founder effect.

    PubMed

    Alsos, Inger Greve; Ehrich, Dorothee; Eidesen, Pernille Bronken; Solstad, Heidi; Westergaard, Kristine Bakke; Schönswetter, Peter; Tribsch, Andreas; Birkeland, Siri; Elven, Reidar; Brochmann, Christian

    2015-04-15

    Long-distance dispersal (LDD) processes influence the founder effect on islands. We use genetic data for 25 Atlantic species and similarities among regional floras to analyse colonization, and test whether the genetic founder effect on five islands is associated with dispersal distance, island size and species traits. Most species colonized postglacially via multiple dispersal events from several source regions situated 280 to >3000 km away, and often not from the closest ones. A strong founder effect was observed for insect-pollinated mixed maters, and it increased with dispersal distance and decreased with island size in accordance with the theory of island biogeography. Only a minor founder effect was observed for wind-pollinated outcrossing species. Colonization patterns were largely congruent, indicating that despite the importance of stochasticity, LDD is mainly determined by common factors, probably dispersal vectors. Our findings caution against a priori assuming a single, close source region in biogeographic analyses. Published by Oxford University Press on behalf of the Annals of Botany Company.

  11. Commensurate distances and similar motifs in genetic congruence and protein interaction networks in yeast

    PubMed Central

    Ye, Ping; Peyser, Brian D; Spencer, Forrest A; Bader, Joel S

    2005-01-01

    Background In a genetic interaction, the phenotype of a double mutant differs from the combined phenotypes of the underlying single mutants. When the single mutants have no growth defect, but the double mutant is lethal or exhibits slow growth, the interaction is termed synthetic lethality or synthetic fitness. These genetic interactions reveal gene redundancy and compensating pathways. Recently available large-scale data sets of genetic interactions and protein interactions in Saccharomyces cerevisiae provide a unique opportunity to elucidate the topological structure of biological pathways and how genes function in these pathways. Results We have defined congruent genes as pairs of genes with similar sets of genetic interaction partners and constructed a genetic congruence network by linking congruent genes. By comparing path lengths in three types of networks (genetic interaction, genetic congruence, and protein interaction), we discovered that high genetic congruence not only exhibits correlation with direct protein interaction linkage but also exhibits commensurate distance with the protein interaction network. However, consistent distances were not observed between genetic and protein interaction networks. We also demonstrated that congruence and protein networks are enriched with motifs that indicate network transitivity, while the genetic network has both transitive (triangle) and intransitive (square) types of motifs. These results suggest that robustness of yeast cells to gene deletions is due in part to two complementary pathways (square motif) or three complementary pathways, any two of which are required for viability (triangle motif). Conclusion Genetic congruence is superior to genetic interaction in prediction of protein interactions and function associations. Genetically interacting pairs usually belong to parallel compensatory pathways, which can generate transitive motifs (any two of three pathways needed) or intransitive motifs (either of two

  12. Heat transport in oscillator chains with long-range interactions coupled to thermal reservoirs

    NASA Astrophysics Data System (ADS)

    Iubini, Stefano; Di Cintio, Pierfrancesco; Lepri, Stefano; Livi, Roberto; Casetti, Lapo

    2018-03-01

    We investigate thermal conduction in arrays of long-range interacting rotors and Fermi-Pasta-Ulam (FPU) oscillators coupled to two reservoirs at different temperatures. The strength of the interaction between two lattice sites decays as a power α of the inverse of their distance. We point out the necessity of distinguishing between energy flows towards or from the reservoirs and those within the system. We show that energy flow between the reservoirs occurs via a direct transfer induced by long-range couplings and a diffusive process through the chain. To this aim, we introduce a decomposition of the steady-state heat current that explicitly accounts for such direct transfer of energy between the reservoir. For 0 ≤α <1 , the direct transfer term dominates, meaning that the system can be effectively described as a set of oscillators each interacting with the thermal baths. Also, the heat current exchanged with the reservoirs depends on the size of the thermalized regions: In the case in which such size is proportional to the system size N , the stationary current is independent on N . For α >1 , heat transport mostly occurs through diffusion along the chain: For the rotors transport is normal, while for FPU the data are compatible with an anomalous diffusion, possibly with an α -dependent characteristic exponent.

  13. Heat transport in oscillator chains with long-range interactions coupled to thermal reservoirs.

    PubMed

    Iubini, Stefano; Di Cintio, Pierfrancesco; Lepri, Stefano; Livi, Roberto; Casetti, Lapo

    2018-03-01

    We investigate thermal conduction in arrays of long-range interacting rotors and Fermi-Pasta-Ulam (FPU) oscillators coupled to two reservoirs at different temperatures. The strength of the interaction between two lattice sites decays as a power α of the inverse of their distance. We point out the necessity of distinguishing between energy flows towards or from the reservoirs and those within the system. We show that energy flow between the reservoirs occurs via a direct transfer induced by long-range couplings and a diffusive process through the chain. To this aim, we introduce a decomposition of the steady-state heat current that explicitly accounts for such direct transfer of energy between the reservoir. For 0≤α<1, the direct transfer term dominates, meaning that the system can be effectively described as a set of oscillators each interacting with the thermal baths. Also, the heat current exchanged with the reservoirs depends on the size of the thermalized regions: In the case in which such size is proportional to the system size N, the stationary current is independent on N. For α>1, heat transport mostly occurs through diffusion along the chain: For the rotors transport is normal, while for FPU the data are compatible with an anomalous diffusion, possibly with an α-dependent characteristic exponent.

  14. Unconditional security proof of long-distance continuous-variable quantum key distribution with discrete modulation.

    PubMed

    Leverrier, Anthony; Grangier, Philippe

    2009-05-08

    We present a continuous-variable quantum key distribution protocol combining a discrete modulation and reverse reconciliation. This protocol is proven unconditionally secure and allows the distribution of secret keys over long distances, thanks to a reverse reconciliation scheme efficient at very low signal-to-noise ratio.

  15. Characterization of Greenbeard Genes Involved in Long-Distance Kind Discrimination in a Microbial Eukaryote

    PubMed Central

    Heller, Jens; Zhao, Jiuhai; Rosenfield, Gabriel; Kowbel, David J.; Gladieux, Pierre; Glass, N. Louise

    2016-01-01

    Microorganisms are capable of communication and cooperation to perform social activities. Cooperation can be enforced using kind discrimination mechanisms in which individuals preferentially help or punish others, depending on genetic relatedness only at certain loci. In the filamentous fungus Neurospora crassa, genetically identical asexual spores (germlings) communicate and fuse in a highly regulated process, which is associated with fitness benefits during colony establishment. Recognition and chemotropic interactions between isogenic germlings requires oscillation of the mitogen-activated protein kinase (MAPK) signal transduction protein complex (NRC-1, MEK-2, MAK-2, and the scaffold protein HAM-5) to specialized cell fusion structures termed conidial anastomosis tubes. Using a population of 110 wild N. crassa isolates, we investigated germling fusion between genetically unrelated individuals and discovered that chemotropic interactions are regulated by kind discrimination. Distinct communication groups were identified, in which germlings within one communication group interacted at high frequency, while germlings from different communication groups avoided each other. Bulk segregant analysis followed by whole genome resequencing identified three linked genes (doc-1, doc-2, and doc-3), which were associated with communication group phenotype. Alleles at doc-1, doc-2, and doc-3 fell into five haplotypes that showed transspecies polymorphism. Swapping doc-1 and doc-2 alleles from different communication group strains was necessary and sufficient to confer communication group affiliation. During chemotropic interactions, DOC-1 oscillated with MAK-2 to the tips of conidial anastomosis tubes, while DOC-2 was statically localized to the plasma membrane. Our data indicate that doc-1, doc-2, and doc-3 function as “greenbeard” genes, involved in mediating long-distance kind recognition that involves actively searching for one’s own type, resulting in cooperation

  16. A comprehensive strategy for identifying long-distance mobile peptides in xylem sap.

    PubMed

    Okamoto, Satoru; Suzuki, Takamasa; Kawaguchi, Masayoshi; Higashiyama, Tetsuya; Matsubayashi, Yoshikatsu

    2015-11-01

    There is a growing awareness that secreted pemediate organ-to-organ communication in higher plants. Xylem sap peptidomics is an effective but challenging approach for identifying long-distance mobile peptides. In this study we developed a simple, gel-free purification system that combines o-chlorophenol extraction with HPLC separation. Using this system, we successfully identified seven oligopeptides from soybean xylem sap exudate that had one or more post-transcriptional modifications: glycosylation, sulfation and/or hydroxylation. RNA sequencing and quantitative PCR analyses showed that the peptide-encoding genes are expressed in multiple tissues. We further analyzed the long-distance translocation of four of the seven peptides using gene-encoding peptides with single amino acid substitutions, and identified these four peptides as potential root-to-shoot mobile oligopeptides. Promoter-GUS analysis showed that all four peptide-encoding genes were expressed in the inner tissues of the root endodermis. Moreover, we found that some of these peptide-encoding genes responded to biotic and/or abiotic factors. These results indicate that our purification system provides a comprehensive approach for effectively identifying endogenous small peptides and reinforce the concept that higher plants employ various peptides in root-to-shoot signaling. © 2015 The Authors The Plant Journal © 2015 John Wiley & Sons Ltd.

  17. Effect of long-distance transportation on serum metabolic profiles of steer calves.

    PubMed

    Takemoto, Satoshi; Tomonaga, Shozo; Funaba, Masayuki; Matsui, Tohru

    2017-12-01

    Long-distance transportation is sometimes inevitable in the beef industry because of the geographic separation of major breeding and fattening areas. Long-distance transportation negatively impacts production and health of cattle, which may, at least partly, result from the disturbance of metabolism during and after transportation. However, alteration of metabolism remains elusive in transported cattle. We investigated the effects of transportation on the metabolomic profiles of Holstein steer calves. Non-targeted analysis of serum concentrations of low molecular weight metabolites was performed by gas chromatography mass spectrometry. Transportation affected 38 metabolites in the serum. A pathway analysis suggested that 26, 10, and 10 pathways were affected immediately after transportation, and 3 and 7 days after transportation, respectively. Some pathways were disturbed only immediately after transportation, likely because of feed and water withdrawal during transit. Nicotinate and nicotinamide metabolism, and citric acid cycle were affected for 3 days after transportation, whereas propionate metabolism, phenylalanine and tyrosine metabolism were affected throughout the experiment. Four pathways were not affected immediately after transportation, but were altered thereafter. These results suggested that many metabolic pathways had marked perturbations during transportation. Metabolites such as citric acid, propionate, tyrosine and niacin can be candidate supplements for mitigating transportation-induced adverse effects. © 2017 Japanese Society of Animal Science.

  18. Physiological demands of running during long distance runs and triathlons.

    PubMed

    Hausswirth, C; Lehénaff, D

    2001-01-01

    The aim of this review article is to identify the main metabolic factors which have an influence on the energy cost of running (Cr) during prolonged exercise runs and triathlons. This article proposes a physiological comparison of these 2 exercises and the relationship between running economy and performance. Many terms are used as the equivalent of 'running economy' such as 'oxygen cost', 'metabolic cost', 'energy cost of running', and 'oxygen consumption'. It has been suggested that these expressions may be defined by the rate of oxygen uptake (VO2) at a steady state (i.e. between 60 to 90% of maximal VO2) at a submaximal running speed. Endurance events such as triathlon or marathon running are known to modify biological constants of athletes and should have an influence on their running efficiency. The Cr appears to contribute to the variation found in distance running performance among runners of homogeneous level. This has been shown to be important in sports performance, especially in events like long distance running. In addition, many factors are known or hypothesised to influence Cr such as environmental conditions, participant specificity, and metabolic modifications (e.g. training status, fatigue). The decrease in running economy during a triathlon and/or a marathon could be largely linked to physiological factors such as the enhancement of core temperature and a lack of fluid balance. Moreover, the increase in circulating free fatty acids and glycerol at the end of these long exercise durations bear witness to the decrease in Cr values. The combination of these factors alters the Cr during exercise and hence could modify the athlete's performance in triathlons or a prolonged run.

  19. On the strong influence of molecular interactions over large distances

    NASA Astrophysics Data System (ADS)

    Pfennig, Andreas

    2018-03-01

    Molecular-dynamics simulations of liquid water show deterministic chaos, i.e. an intentionally introduced molecular position shift of an individual molecule increases exponentially by a factor of 10 in 0.23 ps. This is a Lyaponov instability. As soon as it reaches molecular scale, the direction of the resulting shift in molecular motions is unpredictable. The influence of any individual distant particle on an observed molecule will be minute, but the effect will quickly increase to molecular scale and beyond due to this exponential growth. Consequently, any individual particle in the universe will affect the behavior of any molecule within at most 33 ps after the interaction reaches it. A larger distance of the faraway particle does not decrease the influence on an observed molecule, but the effect reaches molecular scale only some ps later. Thus in evaluating the interactions, nearby and faraway molecules have to be equally accounted for. The consequences of this quickly reacting network of interactions on universal scale are fundamental. Even in a strictly deterministic view, molecular behavior is principally unpredictable, and thus has to be regarded random. Corresponding statements apply for any particles interacting. This result leads to a fundamental rethinking of the structure of interactions of molecules and particles as well as the behavior of reality.

  20. Maximal and submaximal oxygen uptakes and blood lactate levels in elite male middle- and long-distance runners.

    PubMed

    Svedenhag, J; Sjödin, B

    1984-10-01

    Physiological characteristics of elite runners from different racing events were studied. Twenty-seven middle- and long-distance runners and two 400-m runners belonging to the Swedish national team in track and field were divided, according to their distance preferences, into six groups from 400 m up to the marathon. The maximal oxygen uptake (VO2 max, ml X kg-1 X min-1) on the treadmill was higher the longer the main distance except for the marathon runners (e.g., 800-1500-m group, 72.1; 5000-10,000-m group, 78.7 ml X kg-1 X min-1). Running economy evaluated from oxygen uptake measurements at 15 km/h (VO2 15) and 20 km/h (VO2 20) did not differ significantly between the groups even though VO2 15 tended to be lower in the long-distance runners. The running velocity corresponding to a blood lactate concentration of 4 mmol/l (vHla 4.0) differed markedly between the groups with the highest value (5.61 m/s) in the 5000-10,000-m group. The oxygen uptake (VO2) at vHla 4.0 in percentage of VO2 max did not differ significantly between the groups. The blood lactate concentration after exhaustion (VO2 max test) was lower in the long-distance runners. In summary, the present study demonstrates differences in physiological characteristics of elite runners specializing in different racing events. The two single (but certainly inter-related) variables in which this was most clearly seen were the maximal oxygen uptake (ml X kg-1 X min-1) and the running velocity corresponding to a blood lactate concentration of 4 mmol/l.

  1. Possibility of long-distance heat transport in weightlessness using supercritical fluids

    NASA Astrophysics Data System (ADS)

    Beysens, D.; Chatain, D.; Nikolayev, V. S.; Ouazzani, J.; Garrabos, Y.

    2010-12-01

    Heat transport over large distances is classically performed with gravity or capillarity driven heat pipes. We investigate here whether the “piston effect,” a thermalization process that is very efficient in weightlessness in compressible fluids, could also be used to perform long-distance heat transfer. Experiments are performed in a modeling heat pipe (16.5 mm long, 3 mm inner diameter closed cylinder), with nearly adiabatic polymethylmethacrylate walls and two copper base plates. The cell is filled with H2 near its gas-liquid critical point (critical temperature: 33 K). Weightlessness is achieved by submitting the fluid to a magnetic force that compensates gravity. Initially the fluid is isothermal. Then heat is sent to one of the bases with an electrical resistance. The instantaneous amount of heat transported by the fluid is measured at the other end. The data are analyzed and compared with a two-dimensional numerical simulation that allows an extrapolation to be made to other fluids (e.g., CO2 , with critical temperature of 300 K). The major result is concerned with the existence of a very fast response at early times that is only limited by the thermal properties of the cell materials. The yield in terms of ratio, injected or transported heat power, does not exceed 10-30% and is limited by the heat capacity of the pipe. These results are valid in a large temperature domain around the critical temperature.

  2. Quantum-limited heat conduction over macroscopic distances

    PubMed Central

    Partanen, Matti; Tan, Kuan Yen; Govenius, Joonas; Lake, Russell E.; Mäkelä, Miika K.; Tanttu, Tuomo; Möttönen, Mikko

    2016-01-01

    The emerging quantum technological apparatuses1, 2, such as the quantum computer3–6, call for extreme performance in thermal engineering7. Cold distant heat sinks are needed for the quantized electric degrees of freedom due to the increasing packaging density and heat dissipation. Importantly, quantum mechanics sets a fundamental upper limit for the flow of information and heat, which is quantified by the quantum of thermal conductance8–10. However, the short distance between the heat-exchanging bodies in the previous experiments11–14 hinders their applicability in quantum technology. Here, we present experimental observations of quantum-limited heat conduction over macroscopic distances extending to a metre. We achieved this improvement of four orders of magnitude in the distance by utilizing microwave photons travelling in superconducting transmission lines. Thus, it seems that quantum-limited heat conduction has no fundamental distance cutoff. This work establishes the integration of normal-metal components into the framework of circuit quantum electrodynamics15–17 which provides a basis for the superconducting quantum computer18–21. Especially, our results facilitate remote cooling of nanoelectronic devices using far-away in-situ-tunable heat sinks22, 23. Furthermore, quantum-limited heat conduction is important in contemporary thermodynamics24, 25. Here, the long distance may lead to ultimately efficient mesoscopic heat engines with promising practical applications26. PMID:27239219

  3. Distance Education. Overview. ERIC Digest No. 44.

    ERIC Educational Resources Information Center

    Naylor, Michele

    Technological advancement has both facilitated and necessitated the development of distance education programming. In developing nations, distance education is often used to provide traditional education like that usually available in conventional institutions in the Western world. Whereas distance education in the Soviet Union focuses on…

  4. Physiological characteristics of elite short- and long-distance triathletes.

    PubMed

    Millet, Grégoire P; Dréano, Patrick; Bentley, David J

    2003-01-01

    The purpose of this study was to compare the physiological responses in cycling and running of elite short-distance (ShD) and long-distance (LD) triathletes. Fifteen elite male triathletes participating in the World Championships were divided into two groups (ShD and LD) and performed a laboratory trial that comprised submaximal treadmill running, maximal then submaximal ergometry cycling and then an additional submaximal run. "In situ" best ShD triathlon performances were also analysed for each athlete. ShD demonstrated a significantly faster swim time than LD whereas .VO(2max) (ml kg(-1) min(-1)), cycling economy (W l(-1) min(-1)), peak power output (.W(peak),W) and ventilatory threshold (%.VO(2max)) were all similar between ShD and LD. Moreover, there were no differences between the two groups in the change (%) in running economy from the first to the second running bout. Swimming time was correlated to .W(peak)(r=-0.76; P<0.05) and economy ( r=-0.89; P<0.01) in the ShD athletes. Also, cycling time in the triathlon was correlated to .W(peak)(r=-0.83; P<0.05) in LD. In conclusion, ShD triathletes had a faster swimming time but did not exhibit different maximal or submaximal physiological characteristics measured in cycling and running than LD triathletes.

  5. Considerations for the Optimal Design of a Two-Way Interactive Distance Education Classroom.

    ERIC Educational Resources Information Center

    Gregg, Joe; Persichitte, Kay

    To make effective use of a two-way interactive distance education system, classroom design should be a primary consideration. A properly designed classroom will enhance content objectives and increase acceptance of this type of instructional delivery. This paper describes key considerations for optimal design. Construction considerations include…

  6. The Feasibility and Usability of RunningCoach: A Remote Coaching System for Long-Distance Runners †

    PubMed Central

    Bajcsy, Ruzena

    2018-01-01

    Studies have shown that about half of the injuries sustained during long-distance running involve the knee. Cadence (steps per minute) has been identified as a factor that is strongly associated with these running-related injuries, making it a worthwhile candidate for further study. As such, it is critical for long-distance runners to minimize their risk of injury by running at an appropriate running cadence. In this paper, we present the results of a study on the feasibility and usability of RunningCoach, a mobile health (mHealth) system that remotely monitors running cadence levels of runners in a continuous fashion, among other variables, and provides immediate feedback to runners in an effort to help them optimize their running cadence. PMID:29320436

  7. Conservative management of femoroacetabular impingement (FAI) in the long distance runner.

    PubMed

    Loudon, Janice K; Reiman, Michael P

    2014-05-01

    Femoroacetabular impingement (FAI) is one cause of anterior hip pain that may occur in a long distance runner. By definition FAI is due to bony abutment of the femoral neck and the acetabulum. This occurs primarily with end-ranges of hip flexion and adduction. An understanding of running mechanics and performing a thorough examination will help the clinician provide an appropriate intervention for these athletes. A course of conservative treatment that includes patient education, manual therapy and strengthening should be tried prior to surgical management. Copyright © 2014 Elsevier Ltd. All rights reserved.

  8. Enhanced long-distance transport of periodic electron beams in an advanced double layer cone-channel target

    NASA Astrophysics Data System (ADS)

    Ji, Yanling; Duan, Tao; Zhou, Weimin; Li, Boyuan; Wu, Fengjuan; Zhang, Zhimeng; Ye, Bin; Wang, Rong; Wu, Chunrong; Tang, Yongjian

    2018-02-01

    An enhanced long-distance transport of periodic electron beams in an advanced double layer cone-channel target is investigated using two-dimensional particle-in-cell simulations. The target consists of a cone attached to a double-layer hollow channel with a near-critical-density inner layer. The periodic electron beams are generated by the combination of ponderomotive force and longitudinal laser electric field. Then a stable electron propagation is achieved in the double-layer channel over a much longer distance without evident divergency, compared with a normal cone-channel target. Detailed simulations show that the much better long-distance collimation and guidance of energetic electrons is attributed to the much stronger electromagnetic fields at the inner wall surfaces. Furthermore, a continuous electron acceleration is obtained by the more intense laser electric fields and extended electron acceleration length in the channel. Our investigation shows that by employing this advanced target, both the forward-going electron energy flux in the channel and the energy coupling efficiency from laser to electrons are about threefold increased in comparison with the normal case.

  9. Multiple-Transportable Carbohydrate Effect on Long-Distance Triathlon Performance.

    PubMed

    Rowlands, David S; Houltham, Stuart D

    2017-08-01

    The ingestion of multiple (2:1 glucose-fructose) transportable carbohydrate in beverages at high rates (>78 g·h) during endurance exercise enhances exogenous carbohydrate oxidation, fluid absorption, gut comfort, and performance relative to glucose alone. However, during long-distance endurance competition, athletes prefer a solid-gel-drink format, and the effect size of multiple-transportable carbohydrate is unknown. This study aimed to determine the effect of multiple-transportable carbohydrate on triathlon competition performance when ingested within bars, gels, and drinks. A double-blind randomized controlled trial was conducted within two national-body sanctioned half-ironman triathlon races held 3 wk apart in 74 well-trained male triathletes (18-60 yr; >2 yr competition experience). Carbohydrate comprising glucose/maltodextrin-fructose (2:1 ratio) or standard isocaloric carbohydrate (glucose/maltodextrin only) was ingested before (94 g) and during the cycle (2.5 g·km) and run (7.8 g·km) sections, averaging 78.6 ± 6.6 g·h, partitioned to bars (25%), gels (35%), and drink (40%). Postrace, 0- to 10-unit Likert-type scales were completed to assess gut comfort and energy. The trial returned low dropout rate (9%), high compliance, and sensitivity (typical error 2.2%). The effect of multiple-transportable carbohydrate on performance time was -0.53% (95% confidence interval = -1.30% to 0.24%; small benefit threshold = -0.54%), with likelihood-based risk analysis supporting adoption (benefit-harm ratio = 48.9%:0.3%; odds ratio = 285:1). Covariate adjustments for preexercise body weight and heat stress had negligible impact performance. Multiple-transportable carbohydrate possibly lowered nausea during the swim and bike; otherwise, effects on gut comfort and perceived energy were negligible. Multiple-transportable (2:1 maltodextrin/glucose-fructose) compared with single-transportable carbohydrate ingested in differing format provided a small benefit to long-distance

  10. Measurement of the phase difference between short- and long-distance amplitudes in the {{B} ^+} → {{{K}} ^+} {μ ^+μ ^-} decay

    NASA Astrophysics Data System (ADS)

    Aaij, R.; Adeva, B.; Adinolfi, M.; Ajaltouni, Z.; Akar, S.; Albrecht, J.; Alessio, F.; Alexander, M.; Ali, S.; Alkhazov, G.; Alvarez Cartelle, P.; Alves, A. A.; Amato, S.; Amerio, S.; Amhis, Y.; An, L.; Anderlini, L.; Andreassi, G.; Andreotti, M.; Andrews, J. E.; Appleby, R. B.; Archilli, F.; d'Argent, P.; Arnau Romeu, J.; Artamonov, A.; Artuso, M.; Aslanides, E.; Auriemma, G.; Baalouch, M.; Babuschkin, I.; Bachmann, S.; Back, J. J.; Badalov, A.; Baesso, C.; Baker, S.; Balagura, V.; Baldini, W.; Barlow, R. J.; Barschel, C.; Barsuk, S.; Barter, W.; Baszczyk, M.; Batozskaya, V.; Batsukh, B.; Battista, V.; Bay, A.; Beaucourt, L.; Beddow, J.; Bedeschi, F.; Bediaga, I.; Bel, L. J.; Bellee, V.; Belloli, N.; Belous, K.; Belyaev, I.; Ben-Haim, E.; Bencivenni, G.; Benson, S.; Berezhnoy, A.; Bernet, R.; Bertolin, A.; Betancourt, C.; Betti, F.; Bettler, M.-O.; van Beuzekom, M.; Bezshyiko, Ia.; Bifani, S.; Billoir, P.; Bird, T.; Birnkraut, A.; Bitadze, A.; Bizzeti, A.; Blake, T.; Blanc, F.; Blouw, J.; Blusk, S.; Bocci, V.; Boettcher, T.; Bondar, A.; Bondar, N.; Bonivento, W.; Bordyuzhin, I.; Borgheresi, A.; Borghi, S.; Borisyak, M.; Borsato, M.; Bossu, F.; Boubdir, M.; Bowcock, T. J. V.; Bowen, E.; Bozzi, C.; Braun, S.; Britsch, M.; Britton, T.; Brodzicka, J.; Buchanan, E.; Burr, C.; Bursche, A.; Buytaert, J.; Cadeddu, S.; Calabrese, R.; Calvi, M.; Calvo Gomez, M.; Camboni, A.; Campana, P.; Campora Perez, D. H.; Capriotti, L.; Carbone, A.; Carboni, G.; Cardinale, R.; Cardini, A.; Carniti, P.; Carson, L.; Carvalho Akiba, K.; Casse, G.; Cassina, L.; Castillo Garcia, L.; Cattaneo, M.; Cavallero, G.; Cenci, R.; Chamont, D.; Charles, M.; Charpentier, Ph.; Chatzikonstantinidis, G.; Chefdeville, M.; Chen, S.; Cheung, S.-F.; Chobanova, V.; Chrzaszcz, M.; Cid Vidal, X.; Ciezarek, G.; Clarke, P. E. L.; Clemencic, M.; Cliff, H. V.; Closier, J.; Coco, V.; Cogan, J.; Cogneras, E.; Cogoni, V.; Cojocariu, L.; Collazuol, G.; Collins, P.; Comerma-Montells, A.; Contu, A.; Cook, A.; Coombs, G.; Coquereau, S.; Corti, G.; Corvo, M.; Costa Sobral, C. M.; Couturier, B.; Cowan, G. A.; Craik, D. C.; Crocombe, A.; Cruz Torres, M.; Cunliffe, S.; Currie, R.; D'Ambrosio, C.; Da Cunha Marinho, F.; Dall'Occo, E.; Dalseno, J.; David, P. N. Y.; Davis, A.; De Bruyn, K.; De Capua, S.; De Cian, M.; De Miranda, J. M.; De Paula, L.; De Serio, M.; De Simone, P.; Dean, C.-T.; Decamp, D.; Deckenhoff, M.; Del Buono, L.; Demmer, M.; Dendek, A.; Derkach, D.; Deschamps, O.; Dettori, F.; Dey, B.; Di Canto, A.; Dijkstra, H.; Dordei, F.; Dorigo, M.; Dosil Suárez, A.; Dovbnya, A.; Dreimanis, K.; Dufour, L.; Dujany, G.; Dungs, K.; Durante, P.; Dzhelyadin, R.; Dziurda, A.; Dzyuba, A.; Déléage, N.; Easo, S.; Ebert, M.; Egede, U.; Egorychev, V.; Eidelman, S.; Eisenhardt, S.; Eitschberger, U.; Ekelhof, R.; Eklund, L.; Ely, S.; Esen, S.; Evans, H. M.; Evans, T.; Falabella, A.; Farley, N.; Farry, S.; Fay, R.; Fazzini, D.; Ferguson, D.; Fernandez Prieto, A.; Ferrari, F.; Ferreira Rodrigues, F.; Ferro-Luzzi, M.; Filippov, S.; Fini, R. A.; Fiore, M.; Fiorini, M.; Firlej, M.; Fitzpatrick, C.; Fiutowski, T.; Fleuret, F.; Fohl, K.; Fontana, M.; Fontanelli, F.; Forshaw, D. C.; Forty, R.; Franco Lima, V.; Frank, M.; Frei, C.; Fu, J.; Funk, W.; Furfaro, E.; Färber, C.; Gallas Torreira, A.; Galli, D.; Gallorini, S.; Gambetta, S.; Gandelman, M.; Gandini, P.; Gao, Y.; Garcia Martin, L. M.; García Pardiñas, J.; Garra Tico, J.; Garrido, L.; Garsed, P. J.; Gascon, D.; Gaspar, C.; Gavardi, L.; Gazzoni, G.; Gerick, D.; Gersabeck, E.; Gersabeck, M.; Gershon, T.; Ghez, Ph.; Gianì, S.; Gibson, V.; Girard, O. G.; Giubega, L.; Gizdov, K.; Gligorov, V. V.; Golubkov, D.; Golutvin, A.; Gomes, A.; Gorelov, I. V.; Gotti, C.; Graciani Diaz, R.; Granado Cardoso, L. A.; Graugés, E.; Graverini, E.; Graziani, G.; Grecu, A.; Griffith, P.; Grillo, L.; Gruberg Cazon, B. R.; Grünberg, O.; Gushchin, E.; Guz, Yu.; Gys, T.; Göbel, C.; Hadavizadeh, T.; Hadjivasiliou, C.; Haefeli, G.; Haen, C.; Haines, S. C.; Hall, S.; Hamilton, B.; Han, X.; Hansmann-Menzemer, S.; Harnew, N.; Harnew, S. T.; Harrison, J.; Hatch, M.; He, J.; Head, T.; Heister, A.; Hennessy, K.; Henrard, P.; Henry, L.; van Herwijnen, E.; Heß, M.; Hicheur, A.; Hill, D.; Hombach, C.; Hopchev, H.; Hulsbergen, W.; Humair, T.; Hushchyn, M.; Hutchcroft, D.; Idzik, M.; Ilten, P.; Jacobsson, R.; Jaeger, A.; Jalocha, J.; Jans, E.; Jawahery, A.; Jiang, F.; John, M.; Johnson, D.; Jones, C. R.; Joram, C.; Jost, B.; Jurik, N.; Kandybei, S.; Karacson, M.; Kariuki, J. M.; Karodia, S.; Kecke, M.; Kelsey, M.; Kenzie, M.; Ketel, T.; Khairullin, E.; Khanji, B.; Khurewathanakul, C.; Kirn, T.; Klaver, S.; Klimaszewski, K.; Koliiev, S.; Kolpin, M.; Komarov, I.; Koopman, R. F.; Koppenburg, P.; Kosmyntseva, A.; Kozachuk, A.; Kozeiha, M.; Kravchuk, L.; Kreplin, K.; Kreps, M.; Krokovny, P.; Kruse, F.; Krzemien, W.; Kucewicz, W.; Kucharczyk, M.; Kudryavtsev, V.; Kuonen, A. K.; Kurek, K.; Kvaratskheliya, T.; Lacarrere, D.; Lafferty, G.; Lai, A.; Lanfranchi, G.; Langenbruch, C.; Latham, T.; Lazzeroni, C.; Le Gac, R.; van Leerdam, J.; Leflat, A.; Lefrançois, J.; Lefèvre, R.; Lemaitre, F.; Lemos Cid, E.; Leroy, O.; Lesiak, T.; Leverington, B.; Li, T.; Li, Y.; Likhomanenko, T.; Lindner, R.; Linn, C.; Lionetto, F.; Liu, X.; Loh, D.; Longstaff, I.; Lopes, J. H.; Lucchesi, D.; Lucio Martinez, M.; Luo, H.; Lupato, A.; Luppi, E.; Lupton, O.; Lusiani, A.; Lyu, X.; Machefert, F.; Maciuc, F.; Maev, O.; Maguire, K.; Malde, S.; Malinin, A.; Maltsev, T.; Manca, G.; Mancinelli, G.; Manning, P.; Maratas, J.; Marchand, J. F.; Marconi, U.; Marin Benito, C.; Marinangeli, M.; Marino, P.; Marks, J.; Martellotti, G.; Martin, M.; Martinelli, M.; Martinez Santos, D.; Martinez Vidal, F.; Martins Tostes, D.; Massacrier, L. M.; Massafferri, A.; Matev, R.; Mathad, A.; Mathe, Z.; Matteuzzi, C.; Mauri, A.; Maurice, E.; Maurin, B.; Mazurov, A.; McCann, M.; McNab, A.; McNulty, R.; Meadows, B.; Meier, F.; Meissner, M.; Melnychuk, D.; Merk, M.; Merli, A.; Michielin, E.; Milanes, D. A.; Minard, M.-N.; Mitzel, D. S.; Mogini, A.; Molina Rodriguez, J.; Monroy, I. A.; Monteil, S.; Morandin, M.; Morawski, P.; Mordà, A.; Morello, M. J.; Morgunova, O.; Moron, J.; Morris, A. B.; Mountain, R.; Muheim, F.; Mulder, M.; Mussini, M.; Müller, D.; Müller, J.; Müller, K.; Müller, V.; Naik, P.; Nakada, T.; Nandakumar, R.; Nandi, A.; Nasteva, I.; Needham, M.; Neri, N.; Neubert, S.; Neufeld, N.; Neuner, M.; Nguyen, T. D.; Nguyen-Mau, C.; Nieswand, S.; Niet, R.; Nikitin, N.; Nikodem, T.; Nogay, A.; Novoselov, A.; O'Hanlon, D. P.; Oblakowska-Mucha, A.; Obraztsov, V.; Ogilvy, S.; Oldeman, R.; Onderwater, C. J. G.; Otalora Goicochea, J. M.; Otto, A.; Owen, P.; Oyanguren, A.; Pais, P. R.; Palano, A.; Palombo, F.; Palutan, M.; Papanestis, A.; Pappagallo, M.; Pappalardo, L. L.; Parker, W.; Parkes, C.; Passaleva, G.; Pastore, A.; Patel, G. D.; Patel, M.; Patrignani, C.; Pearce, A.; Pellegrino, A.; Penso, G.; Pepe Altarelli, M.; Perazzini, S.; Perret, P.; Pescatore, L.; Petridis, K.; Petrolini, A.; Petrov, A.; Petruzzo, M.; Picatoste Olloqui, E.; Pietrzyk, B.; Pikies, M.; Pinci, D.; Pistone, A.; Piucci, A.; Placinta, V.; Playfer, S.; Plo Casasus, M.; Poikela, T.; Polci, F.; Poluektov, A.; Polyakov, I.; Polycarpo, E.; Pomery, G. J.; Popov, A.; Popov, D.; Popovici, B.; Poslavskii, S.; Potterat, C.; Price, E.; Price, J. D.; Prisciandaro, J.; Pritchard, A.; Prouve, C.; Pugatch, V.; Puig Navarro, A.; Punzi, G.; Qian, W.; Quagliani, R.; Rachwal, B.; Rademacker, J. H.; Rama, M.; Ramos Pernas, M.; Rangel, M. S.; Raniuk, I.; Ratnikov, F.; Raven, G.; Redi, F.; Reichert, S.; dos Reis, A. C.; Remon Alepuz, C.; Renaudin, V.; Ricciardi, S.; Richards, S.; Rihl, M.; Rinnert, K.; Rives Molina, V.; Robbe, P.; Rodrigues, A. B.; Rodrigues, E.; Rodriguez Lopez, J. A.; Rodriguez Perez, P.; Rogozhnikov, A.; Roiser, S.; Rollings, A.; Romanovskiy, V.; Romero Vidal, A.; Ronayne, J. W.; Rotondo, M.; Rudolph, M. S.; Ruf, T.; Ruiz Valls, P.; Saborido Silva, J. J.; Sadykhov, E.; Sagidova, N.; Saitta, B.; Salustino Guimaraes, V.; Sanchez Mayordomo, C.; Sanmartin Sedes, B.; Santacesaria, R.; Santamarina Rios, C.; Santimaria, M.; Santovetti, E.; Sarti, A.; Satriano, C.; Satta, A.; Saunders, D. M.; Savrina, D.; Schael, S.; Schellenberg, M.; Schiller, M.; Schindler, H.; Schlupp, M.; Schmelling, M.; Schmelzer, T.; Schmidt, B.; Schneider, O.; Schopper, A.; Schubert, K.; Schubiger, M.; Schune, M.-H.; Schwemmer, R.; Sciascia, B.; Sciubba, A.; Semennikov, A.; Sergi, A.; Serra, N.; Serrano, J.; Sestini, L.; Seyfert, P.; Shapkin, M.; Shapoval, I.; Shcheglov, Y.; Shears, T.; Shekhtman, L.; Shevchenko, V.; Siddi, B. G.; Silva Coutinho, R.; Silva de Oliveira, L.; Simi, G.; Simone, S.; Sirendi, M.; Skidmore, N.; Skwarnicki, T.; Smith, E.; Smith, I. T.; Smith, J.; Smith, M.; Snoek, H.; Soares Lavra, l.; Sokoloff, M. D.; Soler, F. J. P.; Souza De Paula, B.; Spaan, B.; Spradlin, P.; Sridharan, S.; Stagni, F.; Stahl, M.; Stahl, S.; Stefko, P.; Stefkova, S.; Steinkamp, O.; Stemmle, S.; Stenyakin, O.; Stevens, H.; Stevenson, S.; Stoica, S.; Stone, S.; Storaci, B.; Stracka, S.; Straticiuc, M.; Straumann, U.; Sun, L.; Sutcliffe, W.; Swientek, K.; Syropoulos, V.; Szczekowski, M.; Szumlak, T.; T'Jampens, S.; Tayduganov, A.; Tekampe, T.; Tellarini, G.; Teubert, F.; Thomas, E.; van Tilburg, J.; Tilley, M. J.; Tisserand, V.; Tobin, M.; Tolk, S.; Tomassetti, L.; Tonelli, D.; Topp-Joergensen, S.; Toriello, F.; Tournefier, E.; Tourneur, S.; Trabelsi, K.; Traill, M.; Tran, M. T.; Tresch, M.; Trisovic, A.; Tsaregorodtsev, A.; Tsopelas, P.; Tully, A.; Tuning, N.; Ukleja, A.; Ustyuzhanin, A.; Uwer, U.; Vacca, C.; Vagnoni, V.; Valassi, A.; Valat, S.; Valenti, G.; Vazquez Gomez, R.; Vazquez Regueiro, P.; Vecchi, S.; van Veghel, M.; Velthuis, J. J.; Veltri, M.; Veneziano, G.; Venkateswaran, A.; Vernet, M.; Vesterinen, M.; Viana Barbosa, J. V.; Viaud, B.; Vieira, D.; Vieites Diaz, M.; Viemann, H.; Vilasis-Cardona, X.; Vitti, M.; Volkov, V.; Vollhardt, A.; Voneki, B.; Vorobyev, A.; Vorobyev, V.; Voß, C.; de Vries, J. A.; Vázquez Sierra, C.; Waldi, R.; Wallace, C.; Wallace, R.; Walsh, J.; Wang, J.; Ward, D. R.; Wark, H. M.; Watson, N. K.; Websdale, D.; Weiden, A.; Whitehead, M.; Wicht, J.; Wilkinson, G.; Wilkinson, M.; Williams, M.; Williams, M. P.; Williams, M.; Williams, T.; Wilson, F. F.; Wimberley, J.; Wishahi, J.; Wislicki, W.; Witek, M.; Wormser, G.; Wotton, S. A.; Wraight, K.; Wyllie, K.; Xie, Y.; Xing, Z.; Xu, Z.; Yang, Z.; Yao, Y.; Yin, H.; Yu, J.; Yuan, X.; Yushchenko, O.; Zarebski, K. A.; Zavertyaev, M.; Zhang, L.; Zhang, Y.; Zhang, Y.; Zhelezov, A.; Zheng, Y.; Zhu, X.; Zhukov, V.; Zucchelli, S.

    2017-03-01

    A measurement of the phase difference between the short- and long-distance contributions to the {{B} ^+} → {{{K}} ^+} {μ ^+μ ^-} decay is performed by analysing the dimuon mass distribution. The analysis is based on pp collision data corresponding to an integrated luminosity of 3 fb^{-1} collected by the LHCb experiment in 2011 and 2012. The long-distance contribution to the {{B} ^+} → {{{K}} ^+} {μ ^+μ ^-} decay is modelled as a sum of relativistic Breit-Wigner amplitudes representing different vector meson resonances decaying to muon pairs, each with their own magnitude and phase. The measured phases of the {{J}/ψ } and ψ {(2S)} resonances are such that the interference with the short-distance component in dimuon mass regions far from their pole masses is small. In addition, constraints are placed on the Wilson coefficients, C9 and C_{10}, and the branching fraction of the short-distance component is measured.

  11. Aspiring to physical health: The role of aspirations for physical health in facilitating long-term tobacco abstinence

    PubMed Central

    Niemiec, Christopher P.; Ryan, Richard M.; Deci, Edward L.; Williams, Geoffrey C.

    2009-01-01

    Objective To assess aspirations for physical health over 18 months. To examine whether maintained importance of aspirations for physical health mediated and/or moderated the effect of an intensive intervention on long-term tobacco abstinence. Methods Participants were randomly assigned to an intervention based on self-determination theory or to community care, and provided data at baseline and at 18 and 30 months post-randomization. Results Aspirations for physical health were better maintained over 18 months among participants in the intervention (mean change = .05), relative to community care (mean change = -.13), t = 2.66, p < .01. Maintained importance of aspirations for physical health partially mediated the treatment condition effects on seven-day point prevalence tobacco abstinence (z′ = 1.68, p < .01) and the longest number of days not smoking (z′ = 2.16, p < .01), and interacted with treatment condition to facilitate the longest number of days not smoking (β = .08, p < .05). Conclusion Maintained importance of aspirations for physical health facilitated tobacco abstinence. Practice implications Smokers may benefit from discussing aspirations for physical health within autonomy-supportive interventions. Patients may benefit from discussing aspirations during counseling about therapeutic lifestyle change and medication use. PMID:18838243

  12. Aspiring to physical health: the role of aspirations for physical health in facilitating long-term tobacco abstinence.

    PubMed

    Niemiec, Christopher P; Ryan, Richard M; Deci, Edward L; Williams, Geoffrey C

    2009-02-01

    To assess aspirations for physical health over 18 months. To examine whether maintained importance of aspirations for physical health mediated and/or moderated the effect of an intensive intervention on long-term tobacco abstinence. Participants were randomly assigned to an intervention based on self-determination theory or to community care, and provided data at baseline and at 18 and 30 months post-randomization. Aspirations for physical health were better maintained over 18 months among participants in the intervention (mean change=.05), relative to community care (mean change=-.13), t=2.66, p<.01. Maintained importance of aspirations for physical health partially mediated the treatment condition effects on seven-day point prevalence tobacco abstinence (z'=1.68, p<.01) and the longest number of days not smoking (z'=2.16, p<.01), and interacted with treatment condition to facilitate the longest number of days not smoking (beta=.08, p<.05). Maintained importance of aspirations for physical health facilitated tobacco abstinence. Smokers may benefit from discussing aspirations for physical health within autonomy-supportive interventions. Patients may benefit from discussing aspirations during counseling about therapeutic lifestyle change and medication use.

  13. On the theory of Lorentz gases with long range interactions

    NASA Astrophysics Data System (ADS)

    Nota, Alessia; Simonella, Sergio; Velázquez, Juan J. L.

    We construct and study the stochastic force field generated by a Poisson distribution of sources at finite density, x1,x2,…, in ℝ3 each of them yielding a long range potential QiΦ(x - xi) with possibly different charges Qi ∈ ℝ. The potential Φ is assumed to behave typically as |x|-s for large |x|, with s > 1/2. We will denote the resulting random field as “generalized Holtsmark field”. We then consider the dynamics of one tagged particle in such random force fields, in several scaling limits where the mean free path is much larger than the average distance between the scatterers. We estimate the diffusive time scale and identify conditions for the vanishing of correlations. These results are used to obtain appropriate kinetic descriptions in terms of a linear Boltzmann or Landau evolution equation depending on the specific choices of the interaction potential.

  14. On chemical distances and shape theorems in percolation models with long-range correlations

    NASA Astrophysics Data System (ADS)

    Drewitz, Alexander; Ráth, Balázs; Sapozhnikov, Artëm

    2014-08-01

    In this paper, we provide general conditions on a one parameter family of random infinite subsets of {{Z}}^d to contain a unique infinite connected component for which the chemical distances are comparable to the Euclidean distance. In addition, we show that these conditions also imply a shape theorem for the corresponding infinite connected component. By verifying these conditions for specific models, we obtain novel results about the structure of the infinite connected component of the vacant set of random interlacements and the level sets of the Gaussian free field. As a byproduct, we obtain alternative proofs to the corresponding results for random interlacements in the work of Černý and Popov ["On the internal distance in the interlacement set," Electron. J. Probab. 17(29), 1-25 (2012)], and while our main interest is in percolation models with long-range correlations, we also recover results in the spirit of the work of Antal and Pisztora ["On the chemical distance for supercritical Bernoulli percolation," Ann Probab. 24(2), 1036-1048 (1996)] for Bernoulli percolation. Finally, as a corollary, we derive new results about the (chemical) diameter of the largest connected component in the complement of the trace of the random walk on the torus.

  15. Theme: Distance Education.

    ERIC Educational Resources Information Center

    Whittington, M. Susie, Ed.; And Others

    1994-01-01

    Includes "Next Best Thing to Being There" (Whittington); "Taking the Distance out of Distance Education" (Miller, King); "Preparing a Course for Distance Delivery" (Newcomb); "Team Teaching via Two-Way Interactive Video" (Nichols, Trout); "Using the Ag Ed Network" (Peal); "Student's Perspective" (Schoellhorn); "Need for Instruction in Agriculture…

  16. Species-specific defence responses facilitate conspecifics and inhibit heterospecifics in above–belowground herbivore interactions

    PubMed Central

    Huang, Wei; Siemann, Evan; Xiao, Li; Yang, Xuefang; Ding, Jianqing

    2014-01-01

    Conspecific and heterospecific aboveground and belowground herbivores often occur together in nature and their interactions may determine community structure. Here we show how aboveground adults and belowground larvae of the tallow tree specialist beetle Bikasha collaris and multiple heterospecific aboveground species interact to determine herbivore performance. Conspecific aboveground adults facilitate belowground larvae, but other aboveground damage inhibits larvae or has no effect. Belowground larvae increase conspecific adult feeding, but decrease heterospecific aboveground insect feeding and abundance. Chemical analyses and experiments with plant populations varying in phenolics show that all these positive and negative effects on insects are closely related to root and shoot tannin concentrations. Our results show that specific plant herbivore responses allow herbivore facilitation and inhibition to co-occur, likely shaping diverse aboveground and belowground communities. Considering species-specific responses of plants is critical for teasing apart inter- and intraspecific interactions in aboveground and belowground compartments. PMID:25241651

  17. Warming weakens facilitative interactions between decomposers and detritivores, and modifies freshwater ecosystem functioning.

    PubMed

    Bernabé, Tiago N; de Omena, Paula M; Santos, Viviane Piccin Dos; de Siqueira, Virgínia M; de Oliveira, Valéria M; Romero, Gustavo Q

    2018-02-27

    Warming is among the major drivers of changes in biotic interactions and, in turn, ecosystem functioning. The decomposition process occurs in a chain of facilitative interactions between detritivores and microorganisms. It remains unclear, however, what effect warming may have on the interrelations between detritivores and microorganisms, and the consequences for the functioning of natural freshwater ecosystems. To address these gaps, we performed a field experiment using tank bromeliads and their associated aquatic fauna. We manipulated the presence of bacteria and detritivorous macroinvertebrates (control, "bacteria," and "bacteria + macroinvertebrates") under ambient and warming scenarios, and analyzed the effects on the microorganisms and ecosystem functioning (detritus mass loss, colored dissolved organic matter, and nitrogen flux). We applied antibiotic solution to eliminate or reduce bacteria from control bromeliads. After 60 days incubation, bacterial density was higher in the presence than in the absence of macroinvertebrates. In the absence of macroinvertebrates, temperature did not influence bacterial density. However, in the presence of macroinvertebrates, bacterial density decreased by 54% with warming. The magnitude of the effects of organisms on ecosystem functioning was higher in the combined presence of bacteria and macroinvertebrates. However, warming reduced the overall positive effects of detritivores on bacterial density, which in turn, cascaded down to ecosystem functioning by decreasing decomposition and nitrogen flux. These results show the existence of facilitative mechanisms between bacteria and detritivores in the decomposition process, which might collapse due to warming. Detritivores seem to contribute to nutrient cycling as they facilitate bacterial populations, probably by increasing nutrient input (feces) in the ecosystem. However, increased temperature mitigated these beneficial effects. Our results add to a growing research body

  18. Long-distance measurement-device-independent quantum key distribution with coherent-state superpositions.

    PubMed

    Yin, H-L; Cao, W-F; Fu, Y; Tang, Y-L; Liu, Y; Chen, T-Y; Chen, Z-B

    2014-09-15

    Measurement-device-independent quantum key distribution (MDI-QKD) with decoy-state method is believed to be securely applied to defeat various hacking attacks in practical quantum key distribution systems. Recently, the coherent-state superpositions (CSS) have emerged as an alternative to single-photon qubits for quantum information processing and metrology. Here, in this Letter, CSS are exploited as the source in MDI-QKD. We present an analytical method that gives two tight formulas to estimate the lower bound of yield and the upper bound of bit error rate. We exploit the standard statistical analysis and Chernoff bound to perform the parameter estimation. Chernoff bound can provide good bounds in the long-distance MDI-QKD. Our results show that with CSS, both the security transmission distance and secure key rate are significantly improved compared with those of the weak coherent states in the finite-data case.

  19. Branched-chain amino acid supplementation and the immune response of long-distance athletes.

    PubMed

    Bassit, Reinaldo A; Sawada, Letícia A; Bacurau, Reury F P; Navarro, Franciso; Martins, Eivor; Santos, Ronaldo V T; Caperuto, Erico C; Rogeri, Patrícia; Costa Rosa, Luís F B P

    2002-05-01

    Intense long-duration exercise has been associated with immunosuppression, which affects natural killer cells, lymphokine-activated killer cells, and lymphocytes. The mechanisms involved, however, are not fully determined and seem to be multifactorial, including endocrine changes and alteration of plasma glutamine concentration. Therefore, we evaluated the effect of branched-chain amino acid supplementation on the immune response of triathletes and long-distance runners. Peripheral blood was collected prior to and immediately after an Olympic Triathlon or a 30k run. Lymphocyte proliferation, cytokine production by cultured cells, and plasma glutamine were measured. After the exercise bout, athletes from the placebo group presented a decreased plasma glutamine concentration that was abolished by branched-chain amino acid supplementation and an increased proliferative response in their peripheral blood mononuclear cells. Those cells also produced, after exercise, less tumor necrosis factor, interleukins-1 and -4, and interferon and 48% more interleukin-2. Supplementation stimulated the production of interleukin-2 and interferon after exercise and a more pronounced decrease in the production of interleukin-4, indicating a diversion toward a Th1 type immune response. Our results indicate that branched-chain amino acid (BCAA) supplementation recovers the ability of peripheral blood mononuclear cells proliferate in response to mitogens after a long distance intense exercise, as well as plasma glutamine concentration. The amino acids also modify the pattern of cytokine production leading to a diversion of the immune response toward a Th1 type of immune response.

  20. Distances to Nearby Galaxies via Long Period Variables

    NASA Astrophysics Data System (ADS)

    Jurcevic, John S.

    A new method of measuring extra-Galactic distances has been developed based on the relationship between the luminosity of red supergiant variable (RSV) stars at optical wavelengths and the period of their luminosity variation. This period-luminosity (PL) relationship has been calibrated with RSVs from the Galactic Perseus OB1 association, the Large Magellanic Cloud, and M33 in the broadband optical R and I-bands, in a narrow part of the I-band at 8250 Å, and in the infrared K-band. By using these RSV PL relations, the distances to a sample of nearby galaxies (M101, NGC 2403, and NGC 2366) were determined. These galaxies were chosen because they had existing Cepheid based distances which allowed for a comparison between the two methods and provided a means of verifying the effectiveness of the RSV PL relation. The galaxies were also chosen to span a range of metallicity to allow an investigation of any effects due to metallicity differences. Photometry in the R-band was obtained over a period of three years for the galaxies with a coverage of 20, 17, and 13 epochs for M101, NGC 2403, and NGC 2366, respectively. By looking for red variable stars with periods in the range 100-1200 days the total number of RSVs discovered in the three galaxies was 123. Assuming a distance modulus for the Large Magellanic Cloud of 18.5 +/- 0.1 mag, single epoch I-band photometry of the RSVs was used to construct random phase PL relations resulting in distance moduli for M101, NGC 2403, and NGC 2366 of 29.40 +/- 0.16, 27.67 +/- 0.16, and 27.86 +/- 0.20 mag, respectively. Similarly, PL relations were also found using phase averaged R-band magnitudes which produced distance moduli of 29.09 +/- 0.16, 27.56 +/- 0.16, and 27.76 +/- 0.21 mag, respectively. These distances have been corrected for extinction by assuming values of E(B - V) = 0.10, 0.04, and 0.04 mag. The distances derived agree with those found via Cepheids which indicates that RSVs provide a very useful new method for measuring

  1. Amide Neighbouring-Group Effects in Peptides: Phenylalanine as Relay Amino Acid in Long-Distance Electron Transfer.

    PubMed

    Nathanael, Joses G; Gamon, Luke F; Cordes, Meike; Rablen, Paul R; Bally, Thomas; Fromm, Katharina M; Giese, Bernd; Wille, Uta

    2018-05-04

    In nature, proteins serve as media for long-distance electron transfer (ET) to carry out redox reactions in distant compartments. This ET occurs either by a single-step superexchange or through a multi-step charge hopping process, which uses side chains of amino acids as stepping stones. In this study we demonstrate that Phe can act as a relay amino acid for long-distance electron hole transfer through peptides. The considerably increased susceptibility of the aromatic ring to oxidation is caused by the lone pairs of neighbouring amide carbonyl groups, which stabilise the Phe radical cation. This neighbouring-amide-group effect helps improve understanding of the mechanism of extracellular electron transfer through conductive protein filaments (pili) of anaerobic bacteria during mineral respiration. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  2. Experience of Adult Facilitators in a Virtual-Reality-Based Social Interaction Program for Children with Autism

    ERIC Educational Resources Information Center

    Ke, Fengfeng; Im, Tami; Xue, Xinrong; Xu, Xinhao; Kim, Namju; Lee, Sungwoong

    2015-01-01

    This phenomenological study explored and described the experiences and perceptions of adult facilitators who facilitated virtual-reality-based social interaction for children with autism. Extensive data were collected from iterative, in-depth interviews; online activities observation; and video analysis. Four salient themes emerged through the…

  3. Capability of long distance 100  GHz FMCW using a single GDD lamp sensor.

    PubMed

    Levanon, Assaf; Rozban, Daniel; Aharon Akram, Avihai; Kopeika, Natan S; Yitzhaky, Yitzhak; Abramovich, Amir

    2014-12-20

    Millimeter wave (MMW)-based imaging systems are required for applications in medicine, homeland security, concealed weapon detection, and space technology. The lack of inexpensive room temperature imaging sensors makes it difficult to provide a suitable MMW system for many of the above applications. A 3D MMW imaging system based on chirp radar was studied previously using a scanning imaging system of a single detector. The radar system requires that the millimeter wave detector will be able to operate as a heterodyne detector. Since the source of radiation is a frequency modulated continuous wave (FMCW), the detected signal as a result of heterodyne detection gives the object's depth information according to value of difference frequency, in addition to the reflectance of the 2D image. New experiments show the capability of long distance FMCW detection by using a large scale Cassegrain projection system, described first (to our knowledge) in this paper. The system presents the capability to employ a long distance of at least 20 m with a low-cost plasma-based glow discharge detector (GDD) focal plane array (FPA). Each point on the object corresponds to a point in the image and includes the distance information. This will enable relatively inexpensive 3D MMW imaging.

  4. Effectiveness of Mobile Learning in Distance Education

    ERIC Educational Resources Information Center

    Yousuf, Muhammad Imran

    2007-01-01

    The main aim of this research is to better understand and measure students' attitudes and perceptions towards the importance of mobile learning in distance education. Results of this survey clearly indicate that facilitating mobile learning can improve the entire distance education by enhancing ways of communication among distance learners, tutors…

  5. Enhancing Practice Improvement by Facilitating Practitioner Interactivity: New Roles for Providers of Continuing Medical Education

    ERIC Educational Resources Information Center

    Parboosingh, I. John; Reed, Virginia A.; Palmer, James Caldwell; Bernstein, Henry H.

    2011-01-01

    Research into networking and interactivity among practitioners is providing new information that has the potential to enhance the effectiveness of practice improvement initiatives. This commentary reviews the evidence that practitioner interactivity can facilitate emergent learning and behavior change that lead to practice improvements. Insights…

  6. A Managerial Analysis of ATM in Facilitating Distance Education.

    ERIC Educational Resources Information Center

    Littman, Marlyn Kemper

    In this paper, the fundamental characteristics and capabilities of ATM (Asynchronous Transfer Mode) networks in a distance learning environment are examined. Current and projected ATM applications are described, and issues and challenges associated with developing ATM networking solutions for instructional delivery are explored. Other topics…

  7. Barriers and Facilitators of Transition from Pediatric to Adult Long-Term Follow-Up Care in Childhood Cancer Survivors.

    PubMed

    Rosenberg-Yunger, Zahava R S; Klassen, Anne F; Amin, Leila; Granek, Leeat; D'Agostino, Norma M; Boydell, Katherine M; Greenberg, Mark; Barr, Ronald D; Nathan, Paul C

    2013-09-01

    Despite the risk for late effects in adult survivors of cancer in childhood or adolescence, many survivors fail to transition from pediatric to adult long-term follow-up (LTFU) care. The purpose of this study was to identify the barriers and facilitators of transition from pediatric to adult LTFU care. In this qualitative study, 38 Canadian survivors of cancer in childhood or adolescence, currently aged 15-26 years, were interviewed using semi-structured, open-ended questions. Participants belonged to one of four groups: pre-transition (n=10), successful transition (n=11), failed to transition (n=7), and transitioned to an adult center but then dropped out of adult care (n=10). A constructivist grounded theory approach was used to analyze the interview data. This approach consisted of coding transcripts line by line to develop categories and using constant comparison to examine relationships within and across codes and categories. Interviewing continued until saturation was reached. Three interrelated themes were identified that affected the transition process: micro-level patient factors (e.g., due diligence, anxiety), meso-level support factors (e.g., family, friends), and macro-level system factors (e.g., appointments, communication, healthcare providers). Factors could act as facilitators to transition (e.g., family support), barriers to transition (e.g., difficulty booking appointments), or as both a barrier and a facilitator (e.g., anxiety). This study illustrates the interaction between multiple factors that facilitate and/or prevent transition from pediatric to adult LTFU cancer care. A number of recommendations are presented to address potential macro-level system barriers to successful transition.

  8. Long working distance objective lenses for single atom trapping and imaging

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pritchard, J. D., E-mail: jonathan.pritchard@strath.ac.uk; Department of Physics, University of Strathclyde, 107 Rottenrow East, Glasgow G4 0NG; Isaacs, J. A.

    We present a pair of optimized objective lenses with long working distances of 117 mm and 65 mm, respectively, that offer diffraction limited performance for both Cs and Rb wavelengths when imaging through standard vacuum windows. The designs utilise standard catalog lens elements to provide a simple and cost-effective solution. Objective 1 provides NA = 0.175 offering 3 μm resolution whilst objective 2 is optimized for high collection efficiency with NA = 0.29 and 1.8 μm resolution. This flexible design can be further extended for use at shorter wavelengths by simply re-optimising the lens separations.

  9. Multimedia and Interactivity in Distance Learning of Resuscitation Guidelines: A Randomised Controlled Trial

    ERIC Educational Resources Information Center

    Leszczynski, Piotr; Charuta, Anna; Laziuk, Beata; Galazkowski, Robert; Wejnarski, Arkadiusz; Roszak, Magdalena; Kolodziejczak, Barbara

    2018-01-01

    The aim of the study was to conduct a comparative analysis of three forms of knowledge transfer online, taking into account the long-term knowledge growth rate and the satisfaction of students surveyed in respect to distance learning. The cohort of participants for this survey were students of the first degree, studying in the Emergency Medical…

  10. CIDME: Short distances measured with long chirp pulses.

    PubMed

    Doll, Andrin; Qi, Mian; Godt, Adelheid; Jeschke, Gunnar

    2016-12-01

    Frequency-swept pulses have recently been introduced as pump pulses into double electron-electron resonance (DEER) experiments. A limitation of this approach is that the pump pulses need to be short in comparison to dipolar evolution periods. The "chirp-induced dipolar modulation enhancement" (CIDME) pulse sequence introduced in this work circumvents this limitation by means of longitudinal storage during the application of one single or two consecutive pump pulses. The resulting six-pulse sequence is closely related to the five-pulse "relaxation-induced dipolar modulation enhancement" (RIDME) pulse sequence: While dipolar modulation in RIDME is due to stochastic spin flips during longitudinal storage, modulation in CIDME is due to the pump pulse during longitudinal storage. Experimentally, CIDME is examined for Gd-Gd and nitroxide-nitroxide distance determination using a high-power Q-band spectrometer. Since longitudinal storage results in a 50% signal loss, comparisons between DEER using short chirp pump pulses of 64ns duration and CIDME using longer pump pulses are in favor of DEER. While the lower sensitivity restrains the applicability of CIDME for routine distance determination on high-power spectrometers, this result is not to be generalized to spectrometers having lower power and to specialized "non-routine" applications or different types of spin labels. In particular, the advantage of prolonged CIDME pump pulses is demonstrated for experiments at large frequency offset between the pumped and observed spins. At a frequency separation of 1GHz, where broadening due to dipolar pseudo-secular contributions becomes largely suppressed, a Gd-Gd modulation depth larger than 10% is achieved. Moreover, a CIDME experiment at deliberately reduced power underlines the potential of the new technique for spectrometers with lower power, as often encountered at higher microwave frequencies. With longitudinal storage times T below 10μs, however, CIDME appears rather

  11. Barriers and Facilitators to Implementing a Change Initiative in Long-Term Care Using the INTERACT® Quality Improvement Program.

    PubMed

    Tappen, Ruth M; Wolf, David G; Rahemi, Zahra; Engstrom, Gabriella; Rojido, Carolina; Shutes, Jill M; Ouslander, Joseph G

    Implementation of major organizational change initiatives presents a challenge for long-term care leadership. Implementation of the INTERACT® (Interventions to Reduce Acute Care Transfers) quality improvement program, designed to improve the management of acute changes in condition and reduce unnecessary emergency department visits and hospitalizations of nursing home residents, serves as an example to illustrate the facilitators and barriers to major change in long-term care. As part of a larger study of the impact of INTERACT® on rates of emergency department visits and hospitalizations, staff of 71 nursing homes were called monthly to follow-up on their progress and discuss successful facilitating strategies and any challenges and barriers they encountered during the yearlong implementation period. Themes related to barriers and facilitators were identified. Six major barriers to implementation were identified: the magnitude and complexity of the change (35%), instability of facility leadership (27%), competing demands (40%), stakeholder resistance (49%), scarce resources (86%), and technical problems (31%). Six facilitating strategies were also reported: organization-wide involvement (68%), leadership support (41%), use of administrative authority (14%), adequate training (66%), persistence and oversight on the part of the champion (73%), and unfolding positive results (14%). Successful introduction of a complex change such as the INTERACT® quality improvement program in a long-term care facility requires attention to the facilitators and barriers identified in this report from those at the frontline.

  12. From a distance: implications of spontaneous self-distancing for adaptive self-reflection.

    PubMed

    Ayduk, Ozlem; Kross, Ethan

    2010-05-01

    Although recent experimental work indicates that self-distancing facilitates adaptive self-reflection, it remains unclear (a) whether spontaneous self-distancing leads to similar adaptive outcomes, (b) how spontaneous self-distancing relates to avoidance, and (c) how this strategy impacts interpersonal behavior. Three studies examined these issues demonstrating that the more participants spontaneously self-distanced while reflecting on negative memories, the less emotional (Studies 1-3) and cardiovascular (Study 2) reactivity they displayed in the short term. Spontaneous self-distancing was also associated with lower emotional reactivity and intrusive ideation over time (Study 1). The negative association between spontaneous self-distancing and emotional reactivity was mediated by how participants construed their experience (i.e., less recounting relative to reconstruing) rather than avoidance (Studies 1-2). In addition, spontaneous self-distancing was associated with more problem-solving behavior and less reciprocation of negativity during conflicts among couples in ongoing relationships (Study 3). Although spontaneous self-distancing was empirically related to trait rumination, it explained unique variance in predicting key outcomes. 2010 APA, all rights reserved

  13. From a distance: Implications of spontaneous self-distancing for adaptive self-reflection

    PubMed Central

    Ayduk, Özlem; Kross, Ethan

    2010-01-01

    Although recent work experimental work indicates that self-distancing facilitates adaptive self-reflection, it remains unclear (a) whether spontaneously self-distancing leads to similar adaptive outcomes, (b) how spontaneous self-distancing relates to avoidance, and (c) how this strategy impacts interpersonal behavior. Three studies examined these issues demonstrating that the more participants spontaneously self-distanced while reflecting on negative memories, the less emotional (Studies 1–3) and cardiovascular (Study 2) reactivity they displayed in the short-term. Spontaneous self-distancing was also associated with lower emotional reactivity and intrusive ideation over time (Study 1). The negative association between spontaneous self-distancing and emotional reactivity was mediated by how participants construed their experience (i.e., less recounting relative to reconstruing) rather than avoidance (Studies 1–2). In addition, spontaneous self-distancing was associated with more problem-solving behavior and less reciprocation of negativity during conflicts among couples in ongoing relationships (Study 3). Although spontaneous self-distancing was empirically related to trait rumination, it explained unique variance in predicting key outcomes. PMID:20438226

  14. Wide-Spectrum Microscope with a Long Working Distance Aspherical Objective Based on Obscuration Constraint

    PubMed Central

    Wang, Weibo; Wang, Chao; Liu, Jian; Tan, Jiubin

    2016-01-01

    We present an approach for an initial configuration design based on obscuration constraint and on-axis Taylor series expansion to realize the design of long working distance microscope (numerical aperture (NA) = 0.13 and working distance (WD) = 525 mm) with a low obscuration aspherical Schwarzschild objective in wide-spectrum imaging (λ = 400–900 nm). Experiments of the testing on the resolution target and inspection on United States Air Force (USAF) resolution chart and a line charge-coupled device (CCD) (pixel size of 14 μm × 56 μm) with different wavelength light sources (λ = 480 nm, 550 nm, 660 nm, 850 nm) were implemented to verify the validity of the proposed method. PMID:27834874

  15. Localization in a random XY model with long-range interactions: Intermediate case between single-particle and many-body problems

    NASA Astrophysics Data System (ADS)

    Burin, Alexander L.

    2015-09-01

    Many-body localization in an XY model with a long-range interaction is investigated. We show that in the regime of a high strength of disordering compared to the interaction an off-resonant flip-flop spin-spin interaction (hopping) generates the effective Ising interactions of spins in the third order of perturbation theory in a hopping. The combination of hopping and induced Ising interactions for the power-law distance dependent hopping V (R ) ∝R-α always leads to the localization breakdown in a thermodynamic limit of an infinite system at α <3 d /2 where d is a system dimension. The delocalization takes place due to the induced Ising interactions U (R ) ∝R-2 α of "extended" resonant pairs. This prediction is consistent with the numerical finite size scaling in one-dimensional systems. Many-body localization in an XY model is more stable with respect to the long-range interaction compared to a many-body problem with similar Ising and Heisenberg interactions requiring α ≥2 d which makes the practical implementations of this model more attractive for quantum information applications. The full summary of dimension constraints and localization threshold size dependencies for many-body localization in the case of combined Ising and hopping interactions is obtained using this and previous work and it is the subject for the future experimental verification using cold atomic systems.

  16. Long-distance dispersal to oceanic islands: success of plants with multiple diaspore specializations

    PubMed Central

    Vargas, Pablo; Arjona, Yurena; Nogales, Manuel; Heleno, Ruben H.

    2015-01-01

    A great number of scientific papers claim that angiosperm diversification is manifested by an ample differentiation of diaspore traits favouring long-distance seed dispersal. Oceanic islands offer an ideal framework to test whether the acquisition of multiple sets of diaspore traits (syndromes) by a single species results in a wider geographic distribution. To this end, we performed floristic and syndrome analyses and found that diplochorous species (two syndromes) are overrepresented in the recipient flora of the Azores in contrast to that of mainland Europe, but not to mainland Portugal. An additional analysis of inter-island colonization showed a general trend of a higher number of islands colonized by species with a single syndrome (monochorous) and two syndromes than species with no syndrome (unspecialized). Nevertheless, statistical significance for differences in colonization is meagre in some cases, partially due to the low proportion of diplochorous species in Europe (244 of ∼10 000 species), mainland Portugal (89 of 2294 species), and the Azores (9 of 148 species), Canaries (17 of 387 lowland species) and Galápagos (18 of 313 lowland species). Contrary to expectations, this first study shows only a very marginal advantage for long-distance dispersal of species bearing multiple syndromes. PMID:26174146

  17. An Understanding Information Management System for a Real-Time Interactive Distance Education Environment

    ERIC Educational Resources Information Center

    He, Aiguo

    2009-01-01

    A real-time interactive distance lecture is a joint work that should be accomplished by the effort of the lecturer and his students in remote sites. It is important for the lecturer to get understanding information from the students which cannot be efficiently collected by only using video/audio channels between the lecturer and the students. This…

  18. Facilitating Professional Development for Teachers of English Language Learners

    ERIC Educational Resources Information Center

    Molle, Daniella

    2013-01-01

    The study explores the process of facilitation in professional development for educators. The study relies on discourse analysis of interaction among K-12 teachers and administrators in a Midwestern U.S. state during a semester-long professional development program especially designed for educators working with English language learners (ELLs).…

  19. Can Distance Learning Be Used to Teach Automotive Management Skills?

    ERIC Educational Resources Information Center

    Noto, Teresa L.

    2011-01-01

    Today's automotive college students will shape the future of the automobile industry. The success of college-level automotive programs has long been dependent on the students' ability to participate in hands-on classroom based interactions. In this article, distance learning and how it can be used to teach automotive management skills, as well as…

  20. Impact of distance education via interactive videoconferencing on students' course performance and satisfaction.

    PubMed

    Klibanov, Olga M; Dolder, Christian; Anderson, Kevin; Kehr, Heather A; Woods, J Andrew

    2018-03-01

    The impact of distance education via interactive videoconferencing on pharmacy students' performance in a course was assessed after implementation of a distance campus. Students filled out a "Student Demographic Survey" and a "Precourse Knowledge Assessment" at the start of the course and a "Postcourse Knowledge Assessment" and a "Postcourse Student Perceptions Survey" at the end of the course. The primary end point, a comparison of course grades (%) between the main and distance campuses, was examined using the two-sample t-test. We examined the relationships among demographics, campus location, course grades, grade point average, pre- and postcourse knowledge assessments, and postcourse perceptions as our secondary end points with parametric and nonparametric tests. Data from 93 students were included in the analysis [main campus ( n = 81); distance campus ( n = 12)]. Students on the main campus achieved a significantly higher final course grade (87 vs. 81%; P = 0.02). Scores on the Postcourse Knowledge Assessment were also significantly higher compared with those of students on the distance education campus (77 vs. 68%; P = 0.04). Students on both campuses reported self-perceived improvement in their knowledge base regarding various aspects of infectious diseases. Compared with the students on the distance campus, those on the main campus were more likely to subjectively perceive that they had succeeded in the course ( P = 0.04). Our study suggests that students on the main campus achieved a higher final course grade and were more likely to feel that they had succeeded in the course. Students on both campuses reported improvement in knowledge.

  1. Long-distance effects in B→ K^*ℓ ℓ from analyticity

    NASA Astrophysics Data System (ADS)

    Bobeth, Christoph; Chrzaszcz, Marcin; van Dyk, Danny; Virto, Javier

    2018-06-01

    We discuss a novel approach to systematically determine the dominant long-distance contribution to B→ K^*ℓ ℓ decays in the kinematic region where the dilepton invariant mass is below the open charm threshold. This approach provides the most consistent and reliable determination to date and can be used to compute Standard Model predictions for all observables of interest, including the kinematic region where the dilepton invariant mass lies between the J/ψ and the ψ (2S) resonances. We illustrate the power of our results by performing a New Physics fit to the Wilson coefficient C_9. This approach is systematically improvable from theoretical and experimental sides, and applies to other decay modes of the type B→ Vℓ ℓ , B→ Pℓ ℓ and B→ Vγ.

  2. Long-distance dispersal of spruce budworm (Choristoneura fumiferana Clemens) in Minnesota (USA) and Ontario (Canada) via the atmospheric pathway

    Treesearch

    Brian R. Sturtevant; Gary L. Achtemeier; Joseph J. Charney; Dean P. Anderson; Barry J. Cooke; Phillip A. Townsend

    2013-01-01

    Dispersal can play an important role in the population dynamics of forest insects, but the role of long-distance immigration and emigration remains unclear due to the difficulty of quantifying dispersal distance and direction. We designed an agent-based spruce budworm flight behavior model that, when interfaced with temperature, wind speed, and precipitation output...

  3. Longer wings for faster springs - wing length relates to spring phenology in a long-distance migrant across its range.

    PubMed

    Hahn, Steffen; Korner-Nievergelt, Fränzi; Emmenegger, Tamara; Amrhein, Valentin; Csörgő, Tibor; Gursoy, Arzu; Ilieva, Mihaela; Kverek, Pavel; Pérez-Tris, Javier; Pirrello, Simone; Zehtindjiev, Pavel; Salewski, Volker

    2016-01-01

    In migratory birds, morphological adaptations for efficient migratory flight often oppose morphological adaptations for efficient behavior during resident periods. This includes adaptations in wing shape for either flying long distances or foraging in the vegetation and in climate-driven variation of body size. In addition, the timing of migratory flights and particularly the timely arrival at local breeding sites is crucial because fitness prospects depend on site-specific phenology. Thus, adaptations for efficient long-distance flights might be also related to conditions at destination areas. For an obligatory long-distance migrant, the common nightingale, we verified that wing length as the aerodynamically important trait, but not structural body size increased from the western to the eastern parts of the species range. In contrast with expectation from aerodynamic theory, however, wing length did not increase with increasing migration distances. Instead, wing length was associated with the phenology at breeding destinations, namely the speed of local spring green-up. We argue that longer wings are beneficial for adjusting migration speed to local conditions for birds breeding in habitats with fast spring green-up and thus short optimal arrival periods. We suggest that the speed of spring green-up at breeding sites is a fundamental variable determining the timing of migration that fine tune phenotypes in migrants across their range.

  4. Discovery of long-distance gamete dispersal in a lichen-forming ascomycete.

    PubMed

    Ronnås, Cecilia; Werth, Silke; Ovaskainen, Otso; Várkonyi, Gergely; Scheidegger, Christoph; Snäll, Tord

    2017-10-01

    Accurate estimates of gamete and offspring dispersal range are required for the understanding and prediction of spatial population dynamics and species persistence. Little is known about gamete dispersal in fungi, especially in lichen-forming ascomycetes. Here, we estimate the dispersal functions of clonal propagules, gametes and ascospores of the epiphytic lichen Lobaria pulmonaria. We use hierarchical Bayesian parentage analysis, which integrates genetic and ecological information from multiannual colonization and dispersal source data collected in a large, old-growth forest landscape. The effective dispersal range of gametes is several hundred metres to kilometres from potential paternal individuals. By contrast, clonal propagules disperse only tens of metres, and ascospores disperse over several thousand metres. Our study reveals the dispersal distances of individual reproductive units; clonal propagules, gametes and ascospores, which is of great importance for a thorough understanding of the spatial dynamics of ascomycetes. Sexual reproduction occurs between distant individuals. However, whereas gametes and ascospores disperse over long distances, the overall rate of colonization of trees is low. Hence, establishment is the limiting factor for the colonization of new host trees by the lichen in old-growth landscapes. © 2017 The Authors. New Phytologist © 2017 New Phytologist Trust.

  5. Energy cost of swimming of elite long-distance swimmers.

    PubMed

    Zamparo, P; Bonifazi, M; Faina, M; Milan, A; Sardella, F; Schena, F; Capelli, C

    2005-08-01

    The aim of this study was: (1) to assess the energy cost of swimming (C(s), kJ km(-1)) in a group of male (n = 5) and female (n = 5) elite swimmers specialised in long-distance competitions; (2) to evaluate the possible effect of a 2-km trial on the absolute value of C(s). C(s) was assessed during three consecutive 400-m trials covered in a 50-m pool at increasing speeds (v1, v2, v3). After these experiments the subjects swam a 2-km trial at the 10-km race speed (v2km) after which the three 400-m trials were repeated at the same speed as before (v5 = v1, v6 = v2, v7 = v3). C(s) was calculated by dividing the net oxygen uptake at steady state VO2ss by the corresponding average speed (v, m s(-1)). VO2ss was estimated by using back extrapolation technique from breath-to-breath VO2 recorded during the first 30 s of recovery after each test. C(s) increased (from 0.69 kJ m(-1) to 1.27 kJ m(-1)) as a function of v (from 1.29 m s(-1) to 1.50 m s(-1)), its values being comparable to those measured in elite short distance swimmers at similar speeds. In both groups of subjects the speed maintained during the 2-km trial (v2km) was on the average only 1.2% faster than of v2 and v6 (P>0.05), whereas C(s) assessed at the end of the 2-km trial (v2km) turned out to be 21 +/- 26% larger than that assessed at v2 and v6 (P<0.05); the average stroke frequency (SF, cycles min(-1)) during the 2-km trial turned to be about 6% (P<0.05) faster than that assessed at v2 and v6. At v5, C(s) turned out to be 19 +/- 9% (P<0.05) and 22 +/- 27% (0.1 < P = 0.05) larger than at v1 in male and female subjects (respectively). SF was significantly faster (P<0.05, in male subjects) and the distance per stroke (Ds = v/SF) significantly shorter (P<0.05) in female subjects at v5 and v6 than at v1 and v2. These data suggest that the increase of C(s) found after the 2-km trial was likely related to a decrease in propelling efficiency, since the latter is related to the distance per stroke.

  6. Lipopolysaccharide Density and Structure Govern the Extent and Distance of Nanoparticle Interaction with Actual and Model Bacterial Outer Membranes

    DOE PAGES

    Jacobson, Kurt H.; Gunsolus, Ian L.; Kuech, Thomas R.; ...

    2015-07-24

    We report that design of nanomedicines and nanoparticle-based antimicrobial and antifouling formulations, and assessment of the potential implications of nanoparticle release into the environment require understanding nanoparticle interaction with bacterial surfaces. Here we demonstrate electrostatically driven association of functionalized nanoparticles with lipopolysaccharides of Gram-negative bacterial outer membranes and find that lipopolysaccharide structure influences the extent and location of binding relative to the lipid-solution interface. By manipulating the lipopolysaccharide content in Shewanella oneidensis outer membranes, we observed electrostatically driven interaction of cationic gold nanoparticles with the lipopolysaccharide-containing leaflet. We probed this interaction by quartz crystal microbalance with dissipation monitoring (QCM-D) andmore » second harmonic generation (SHG) using solid-supported lipopolysaccharide-containing bilayers. Association of cationic nanoparticles increased with lipopolysaccharide content, while no association of anionic nanoparticles was observed. The harmonic-dependence of QCM-D measurements suggested that a population of the cationic nanoparticles was held at a distance from the outer leaflet-solution interface of bilayers containing smooth lipopolysaccharides (those bearing a long O-polysaccharide). Additionally, smooth lipopolysaccharides held the bulk of the associated cationic particles outside of the interfacial zone probed by SHG. Lastly, our results demonstrate that positively charged nanoparticles are more likely to interact with Gram-negative bacteria than are negatively charged particles, and this interaction occurs primarily through lipopolysaccharides.« less

  7. RUNNING INJURY DEVELOPMENT: THE ATTITUDES OF MIDDLE- AND LONG-DISTANCE RUNNERS AND THEIR COACHES.

    PubMed

    Johansen, Karen Krogh; Hulme, Adam; Damsted, Camma; Ramskov, Daniel; Nielsen, Rasmus Oestergaard

    2017-08-01

    Behavioral science methods have rarely been used in running injury research. Therefore, the attitudes amongst runners and their coaches regarding factors leading to running injuries warrants formal investigation. To investigate the attitudes of middle- and long-distance runners able to compete in national championships and their coaches about factors associated with running injury development. A link to an online survey was distributed to middle- and long-distance runners and their coaches across 25 Danish Athletics Clubs. The main research question was: "Which factors do you believe influence the risk of running injuries?". In response to this question, the athletes and coaches had to click "Yes" or "No" to 19 predefined factors. In addition, they had the possibility to submit a free-text response. A total of 68 athletes and 19 coaches were included in the study. A majority of the athletes (76% [95%CI: 66%; 86%]) and coaches (79% [95%CI: 61%; 97%]) reported "Ignoring pain" as a risk factor for running injury. A majority of the coaches reported "Reduced muscle strength" (79% [95%CI: 61%; 97%]) and "high running distance" (74% [95%CI: 54%; 94%]) to be associated with injury, while half of the runners found "insufficient recovery between running sessions" (53% [95%CI: 47%; 71%]) important. Runners and their coaches emphasize ignoring pain as a factor associated with injury development. The question remains how much running, if any at all, runners having slight symptoms or mild pain, are able to tolerate before these symptoms develop into a running-related injury. 3b.

  8. Experimental realization of SDA-method for the detection of substance at long distance

    NASA Astrophysics Data System (ADS)

    Trofimov, Vyacheslav A.; Denisov, Anton D.; Tikhomirov, Vasily V.

    2013-10-01

    Nowadays, the detection and identification of dangerous substances at long distance (several metres, for example) by using of THz pulse reflected from the object is an important problem. The main problem with this technique is the absorption of THz energy by water vapor. However, using THz pulsed radiation is possible at distance of some metres as it is well-known. Below we demonstrate possibility of THz signal measuring reflected from a flat metallic mirror placed about 3.2 metres from the parabolic mirror. Investigated object is placed before this mirror. Therefore, at present time our measurements contain features of both transmission and reflection modes. The reflecting mirror is used because of weak averaged power of femtosecond laser. This power is about 1 W. Nevertheless, the laser beam splits many times. Therefore, the averaged power falling on the THz emitter decreases at least 8 times. The pulse duration generated by the femtosecond laser is equal to 68 fs. In this mode of measurements we took measurements for a chocolate brick, cookies, a bag made from thick paperboard, many layers of thin papers (paper napkin for computer monitor). In particular, it should be stressed that a spectrum of the measured signal is highly sensitive to a angle position of the flat mirror. Therefore, at long distance the position of object, that reflects the THz pulse, will influence essentially on the measured spectrum. Other very important features of the measurements with the multilayer of paper are the strong modulation of the spectrum of the reflected signal. As a consequence, we see additional frequencies, which correspond to absorption frequencies of various explosives, in the spectrum of the reflected signal. In fact, these substances are absent in our experiment. The last important result consists of unusual influence of the cookies on the measured signal: it becomes strong modulated. Consequently, cookies act as disordered structures.

  9. Long-distance electron transfer by cable bacteria in aquifer sediments

    PubMed Central

    Müller, Hubert; Bosch, Julian; Griebler, Christian; Damgaard, Lars Riis; Nielsen, Lars Peter; Lueders, Tillmann; Meckenstock, Rainer U

    2016-01-01

    The biodegradation of organic pollutants in aquifers is often restricted to the fringes of contaminant plumes where steep countergradients of electron donors and acceptors are separated by limited dispersive mixing. However, long-distance electron transfer (LDET) by filamentous ‘cable bacteria' has recently been discovered in marine sediments to couple spatially separated redox half reactions over centimeter scales. Here we provide primary evidence that such sulfur-oxidizing cable bacteria can also be found at oxic–anoxic interfaces in aquifer sediments, where they provide a means for the direct recycling of sulfate by electron transfer over 1–2-cm distance. Sediments were taken from a hydrocarbon-contaminated aquifer, amended with iron sulfide and saturated with water, leaving the sediment surface exposed to air. Steep geochemical gradients developed in the upper 3 cm, showing a spatial separation of oxygen and sulfide by 9 mm together with a pH profile characteristic for sulfur oxidation by LDET. Bacterial filaments, which were highly abundant in the suboxic zone, were identified by sequencing of 16S rRNA genes and fluorescence in situ hybridization (FISH) as cable bacteria belonging to the Desulfobulbaceae. The detection of similar Desulfobulbaceae at the oxic–anoxic interface of fresh sediment cores taken at a contaminated aquifer suggests that LDET may indeed be active at the capillary fringe in situ. PMID:27058505

  10. Body Space in Social Interactions: A Comparison of Reaching and Comfort Distance in Immersive Virtual Reality

    PubMed Central

    Iachini, Tina; Coello, Yann; Frassinetti, Francesca; Ruggiero, Gennaro

    2014-01-01

    Background Do peripersonal space for acting on objects and interpersonal space for interacting with con-specifics share common mechanisms and reflect the social valence of stimuli? To answer this question, we investigated whether these spaces refer to a similar or different physical distance. Methodology Participants provided reachability-distance (for potential action) and comfort-distance (for social processing) judgments towards human and non-human virtual stimuli while standing still (passive) or walking toward stimuli (active). Principal Findings Comfort-distance was larger than other conditions when participants were passive, but reachability and comfort distances were similar when participants were active. Both spaces were modulated by the social valence of stimuli (reduction with virtual females vs males, expansion with cylinder vs robot) and the gender of participants. Conclusions These findings reveal that peripersonal reaching and interpersonal comfort spaces share a common motor nature and are sensitive, at different degrees, to social modulation. Therefore, social processing seems embodied and grounded in the body acting in space. PMID:25405344

  11. Search for long distance correlations between extensive air showers detected by the EEE network

    NASA Astrophysics Data System (ADS)

    Abbrescia, M.; Baldini, L.; Baldini Ferroli, R.; Batignani, G.; Battaglieri, M.; Boi, S.; Bossini, E.; Carnesecchi, F.; Chiavassa, A.; Cicalo, C.; Cifarelli, L.; Coccetti, F.; Coccia, E.; De Gruttola, D.; De Pasquale, S.; Fabbri, F. L.; Frolov, V.; Galeotti, P.; Garbini, M.; Gemme, G.; Gnesi, I.; Grazzi, S.; Gustavino, C.; Hatzifotiadou, D.; La Rocca, P.; Mandaglio, G.; Maragoto Rodriguez, O.; Maron, G.; Mazziotta, M. N.; Miozzi, S.; Nania, R.; Noferini, F.; Nozzoli, F.; Palmonari, F.; Panareo, M.; Panetta, M. P.; Paoletti, R.; Park, W.; Perasso, L.; Pilo, F.; Piragino, G.; Pisano, S.; Riggi, F.; Righini, G. C.; Ripoli, C.; Sartorelli, G.; Scapparone, E.; Schioppa, M.; Scribano, A.; Selvi, M.; Serci, S.; Squarcia, S.; Taiuti, M.; Terreni, G.; Trifirò, A.; Trimarchi, M.; Vistoli, M. C.; Votano, L.; Williams, M. C. S.; Zheng, L.; Zichichi, A.; Zuyeuski, R.

    2018-02-01

    A search for long distance correlations between individual Extensive Air Showers (EAS) detected by pairs of MRPC telescopes of the Extreme Energy Events (EEE) network was carried out. The search for an anomaly in these events is the purpose of our work. A dataset obtained by all the possible 45 pairs between 10 EEE cluster sites (hosting at least two telescopes), located at relative distances between 86 and 1200km, was analyzed, corresponding to an overall period of 3968 days time exposure. To estimate the possible event excess with respect to the spurious rate, the number of coincidence events was extracted as a function of the time difference between the arrival of the showers in the two sites, from ± 10 s to the smallest time interval where events are still observed. The analysis was done taking into account both the time and orientation correlation between the showers detected by the telescope pairs. A few candidate events with unusually small time difference and angular distance were observed, with a p-value sensibly smaller than a confidence level of 0.05.

  12. Long distance high power optical laser fiber break detection and continuity monitoring systems and methods

    DOEpatents

    Rinzler, Charles C.; Gray, William C.; Faircloth, Brian O.; Zediker, Mark S.

    2016-02-23

    A monitoring and detection system for use on high power laser systems, long distance high power laser systems and tools for performing high power laser operations. In particular, the monitoring and detection systems provide break detection and continuity protection for performing high power laser operations on, and in, remote and difficult to access locations.

  13. The Saharan Aerosol Long-range Transport and Aerosol-Cloud Interaction Experiment (SALTRACE 2013) - An overview

    NASA Astrophysics Data System (ADS)

    Weinzierl, Bernadett; Ansmann, Albert; Reitebuch, Oliver; Freudenthaler, Volker; Müller, Thomas; Kandler, Konrad; Althausen, Dietrich; Chouza, Fernando; Dollner, Maximilian; Farrell, David; Groß, Silke; Heinold, Bernd; Kristensen, Thomas B.; Mayol-Bracero, Olga L.; Omar, Ali; Prospero, Joseph; Sauer, Daniel; Schäfler, Andreas; Toledano, Carlos; Tegen, Ina

    2015-04-01

    Saharan mineral dust is regularly transported over long distances impacting air quality, health, weather and climate thousands of kilometers downwind of the Sahara. During transport, the properties of mineral dust may be modified thereby changing the associated impact on the radiation budget. Although mineral dust is of key importance for the climate system many questions such as the change of the dust size distribution during long-range transport, the role of wet and dry removal mechanisms, and the complex interaction between mineral dust and clouds remain open. To investigate the aging and modification of Saharan mineral dust during long-range transport across the Atlantic Ocean, the Saharan Aerosol Long-range Transport and Aerosol-Cloud-Interaction Experiment (SALTRACE: http://www.pa.op.dlr.de/saltrace) was conducted in June/July 2013. SALTRACE was designed as a closure experiment combining ground-based lidar, in-situ and sun photometer instruments deployed on Cape Verde, Barbados and Puerto Rico, with airborne measurements of the DLR research aircraft Falcon, satellite observations and model simulations. During SALTRACE, mineral dust from five dust outbreaks was studied under different atmospheric conditions and a unique data set on the chemical, microphysical and optical properties of aged mineral dust was gathered. For the first time, Lagrangian sampling of a dust plume in the Cape Verde area on 17 June 2013 which was again measured with the same instrumentation on 21 and 22 June 2013 near Barbados was realized. Further highlights of SALTRACE include the formation and evolution of tropical storm Chantal in a dusty environment and the interaction of dust with mixed-phase clouds. In our presentation, we give an overview of the SALTRACE study, discuss the meteorological situation and the dust transport during SALTRACE and highlight selected results from SALTRACE.

  14. An interactive distance solution for stroke rehabilitation in the home setting - A feasibility study.

    PubMed

    Palmcrantz, Susanne; Borg, Jörgen; Sommerfeld, Disa; Plantin, Jeanette; Wall, Anneli; Ehn, Maria; Sjölinder, Marie; Boman, Inga-Lill

    2017-09-01

    In this study an interactive distance solution (called the DISKO tool) was developed to enable home-based motor training after stroke. The overall aim was to explore the feasibility and safety of using the DISKO-tool, customized for interactive stroke rehabilitation in the home setting, in different rehabilitation phases after stroke. Fifteen patients in three different stages in the continuum of rehabilitation after stroke participated in a home-based training program using the DISKO-tool. The program included 15 training sessions with recurrent follow-ups by the integrated application for video communication with a physiotherapist. Safety and feasibility were assessed from patients, physiotherapists, and a technician using logbooks, interviews, and a questionnaire. Qualitative content analysis and descriptive statistics were used in the analysis. Fourteen out of 15 patients finalized the training period with a mean of 19.5 minutes spent on training at each session. The DISKO-tool was found to be useful and safe by patients and physiotherapists. This study demonstrates the feasibility and safety of the DISKO-tool and provides guidance in further development and testing of interactive distance technology for home rehabilitation, to be used by health care professionals and patients in different phases of rehabilitation after stroke.

  15. Research on numerical simulation and protection of transient process in long-distance slurry transportation pipelines

    NASA Astrophysics Data System (ADS)

    Lan, G.; Jiang, J.; Li, D. D.; Yi, W. S.; Zhao, Z.; Nie, L. N.

    2013-12-01

    The calculation of water-hammer pressure phenomenon of single-phase liquid is already more mature for a pipeline of uniform characteristics, but less research has addressed the calculation of slurry water hammer pressure in complex pipelines with slurry flows carrying solid particles. In this paper, based on the developments of slurry pipelines at home and abroad, the fundamental principle and method of numerical simulation of transient processes are presented, and several boundary conditions are given. Through the numerical simulation and analysis of transient processes of a practical engineering of long-distance slurry transportation pipeline system, effective protection measures and operating suggestions are presented. A model for calculating the water impact of solid and fluid phases is established based on a practical engineering of long-distance slurry pipeline transportation system. After performing a numerical simulation of the transient process, analyzing and comparing the results, effective protection measures and operating advice are recommended, which has guiding significance to the design and operating management of practical engineering of longdistance slurry pipeline transportation system.

  16. Distance Learning: A Way of Life-Long Learning

    DTIC Science & Technology

    2005-09-01

    promise of future benefits. 15. SUBJECT TERMS training, educational technology , distributed learning , distance learning , collaboration, online instruction...knowledge." - Aristotle Introduction Modern learning technology assumes various names: distance learning , distributed training, computer-based...training, web-based learning , or advanced distributed learning . No matter the name, the basic concept is using computer technology for instruction with no

  17. Facilitation shifts paradigms and can amplify coastal restoration efforts.

    PubMed

    Silliman, Brian R; Schrack, Elizabeth; He, Qiang; Cope, Rebecca; Santoni, Amanda; van der Heide, Tjisse; Jacobi, Ralph; Jacobi, Mike; van de Koppel, Johan

    2015-11-17

    Restoration has been elevated as an important strategy to reverse the decline of coastal wetlands worldwide. Current practice in restoration science emphasizes minimizing competition between out-planted propagules to maximize planting success. This paradigm persists despite the fact that foundational theory in ecology demonstrates that positive species interactions are key to organism success under high physical stress, such as recolonization of bare substrate. As evidence of how entrenched this restoration paradigm is, our survey of 25 restoration organizations in 14 states in the United States revealed that >95% of these agencies assume minimizing negative interactions (i.e., competition) between outplants will maximize propagule growth. Restoration experiments in both Western and Eastern Atlantic salt marshes demonstrate, however, that a simple change in planting configuration (placing propagules next to, rather than at a distance from, each other) results in harnessing facilitation and increased yields by 107% on average. Thus, small adjustments in restoration design may catalyze untapped positive species interactions, resulting in significantly higher restoration success with no added cost. As positive interactions between organisms commonly occur in coastal ecosystems (especially in more physically stressful areas like uncolonized substrate) and conservation resources are limited, transformation of the coastal restoration paradigm to incorporate facilitation theory may enhance conservation efforts, shoreline defense, and provisioning of ecosystem services such as fisheries production.

  18. Facilitation shifts paradigms and can amplify coastal restoration efforts

    PubMed Central

    Silliman, Brian R.; Schrack, Elizabeth; He, Qiang; Cope, Rebecca; Santoni, Amanda; van der Heide, Tjisse; Jacobi, Ralph; Jacobi, Mike; van de Koppel, Johan

    2015-01-01

    Restoration has been elevated as an important strategy to reverse the decline of coastal wetlands worldwide. Current practice in restoration science emphasizes minimizing competition between out-planted propagules to maximize planting success. This paradigm persists despite the fact that foundational theory in ecology demonstrates that positive species interactions are key to organism success under high physical stress, such as recolonization of bare substrate. As evidence of how entrenched this restoration paradigm is, our survey of 25 restoration organizations in 14 states in the United States revealed that >95% of these agencies assume minimizing negative interactions (i.e., competition) between outplants will maximize propagule growth. Restoration experiments in both Western and Eastern Atlantic salt marshes demonstrate, however, that a simple change in planting configuration (placing propagules next to, rather than at a distance from, each other) results in harnessing facilitation and increased yields by 107% on average. Thus, small adjustments in restoration design may catalyze untapped positive species interactions, resulting in significantly higher restoration success with no added cost. As positive interactions between organisms commonly occur in coastal ecosystems (especially in more physically stressful areas like uncolonized substrate) and conservation resources are limited, transformation of the coastal restoration paradigm to incorporate facilitation theory may enhance conservation efforts, shoreline defense, and provisioning of ecosystem services such as fisheries production. PMID:26578775

  19. Assessing factors causing severe injuries in crashes of high-deck buses in long-distance driving on freeways.

    PubMed

    Chu, Hsing-Chung

    2014-01-01

    High-deck buses that have a higher center of gravity traveling at an excessive speed have a higher likelihood of causing serious and fatal accidents when drivers lose control of the vehicle. In addition, drivers who suffer from fatigue in long-distance driving increase the likelihood of serious accident. This paper examines the effects of risk factors contributing to severe crashes associated with high-deck buses used for long-distance driving on freeways. An ordered logit and latent class models are used to examine significant factors on the severity of injuries in crashes related to high-deck buses. Driver fatigue, drivers or passengers not wearing a seat belt, reckless driving, drunk driving, crashes occurred between midnight and dawn, and crashes occurred at interchange ramps were found to significantly affect the severity of injuries in crashes involving high-deck buses. Safety policies to prevent severe injuries in crashes involving high deck buses used for long-distance runs on freeways include: (1) restricting drivers from exceeding the limit of daily driving hours and mandating sufficient rest breaks; (2) installing an automatic sleep-warning device in the vehicle; (3) drivers with obstructive sleep apnea syndrome or sleep disorders should be tested and treated before they are allowed to perform long hours of driving tasks; (4) educating the public or even amending the seatbelt legislation to require all passengers to wear a seat belt and thus reduce the chance of ejection from a high-deck bus and prevent serious injuries in a crash while traveling at a higher speed on freeways. Copyright © 2013 Elsevier Ltd. All rights reserved.

  20. Tracking long-distance migration to assess marine pollution impact

    PubMed Central

    Montevecchi, William; Fifield, David; Burke, Chantelle; Garthe, Stefan; Hedd, April; Rail, Jean-François; Robertson, Gregory

    2012-01-01

    Animal tracking provides new means to assess far-reaching environmental impacts. In the aftermath of the Deepwater Horizon explosion in the Gulf of Mexico, a long-distance migrant, the northern gannet (Morus bassanus) suffered the highest oiling among beach-wrecked birds recovered. Analysis of bird-borne tracking data indicated that 25 per cent of their North American population from multiple colonies in eastern Canada migrated to the pollution zone. Findings contrasted sharply with available mark-recapture (band recovery) data. The timing of movement into and out of the Gulf indicates that immature birds would have absorbed most oil-induced mortality. Consequently, one of two outcomes is likely: either a lagged (likely difficult to assess) population decrease, or an undetectable population response buffered by age-related life-history adaptations. Tracking research is especially useful when little information on animal distributions in pollution zones is available, as is the case in the Gulf of Mexico. Ongoing research highlights current risks and conservation concerns. PMID:22012949

  1. The 3D Structure of the Immunoglobulin Heavy-Chain Locus: Implications for Long-Range Genomic Interactions

    PubMed Central

    Jhunjhunwala, Suchit; van Zelm, Menno C.; Peak, Mandy M.; Cutchin, Steve; Riblet, Roy; van Dongen, Jacques J.M.; Grosveld, Frank G.; Knoch, Tobias A.; Murre, Cornelis

    2009-01-01

    SUMMARY The immunoglobulin heavy-chain (Igh) locus is organized into distinct regions that contain multiple variable (VH), diversity (DH), joining (JH) and constant (CH) coding elements. How the Igh locus is structured in 3D space is unknown. To probe the topography of the Igh locus, spatial distance distributions were determined between 12 genomic markers that span the entire Igh locus. Comparison of the distance distributions to computer simulations of alternative chromatin arrangements predicted that the Igh locus is organized into compartments containing clusters of loops separated by linkers. Trilateration and triple-point angle measurements indicated the mean relative 3D positions of the VH, DH, JH, and CH elements, showed compartmentalization and striking conformational changes involving VH and DH-JH elements during early B cell development. In pro-B cells, the entire repertoire of VH regions (2 Mbp) appeared to have merged and juxtaposed to the DH elements, mechanistically permitting long-range genomic interactions to occur with relatively high frequency. PMID:18423198

  2. Colonization of the Scottish islands via long-distance Neolithic transport of red deer (Cervus elaphus).

    PubMed

    Stanton, David W G; Mulville, Jacqueline A; Bruford, Michael W

    2016-04-13

    Red deer (Cervus elaphus) have played a key role in human societies throughout history, with important cultural significance and as a source of food and materials. This relationship can be traced back to the earliest human cultures and continues to the present day. Humans are thought to be responsible for the movement of a considerable number of deer throughout history, although the majority of these movements are poorly described or understood. Studying such translocations allows us to better understand ancient human-wildlife interactions, and in the case of island colonizations, informs us about ancient human maritime practices. This study uses DNA sequences to characterise red deer genetic diversity across the Scottish islands (Inner and Outer Hebrides and Orkney) and mainland using ancient deer samples, and attempts to infer historical colonization events. We show that deer from the Outer Hebrides and Orkney are unlikely to have originated from mainland Scotland, implying that humans introduced red deer from a greater distance. Our results are also inconsistent with an origin from Ireland or Norway, suggesting long-distance maritime travel by Neolithic people to the outer Scottish Isles from an unknown source. Common haplotypes and low genetic differentiation between the Outer Hebrides and Orkney imply common ancestry and/or gene flow across these islands. Close genetic proximity between the Inner Hebrides and Ireland, however, corroborates previous studies identifying mainland Britain as a source for red deer introductions into Ireland. This study provides important information on the processes that led to the current distribution of the largest surviving indigenous land mammal in the British Isles. © 2016 The Authors.

  3. RAPID COMMUNICATIONS: Long-distance quantum teleportation assisted with free-space entanglement distribution

    NASA Astrophysics Data System (ADS)

    Ren, Ji-Gang; Yang, Bin; Yi, Zhen-Huan; Zhou, Fei; Chen, Kai; Peng, Cheng-Zhi; Pan, Jian-Wei

    2009-08-01

    Faithful long-distance quantum teleportation necessitates prior entanglement distribution between two communicated locations. The particle carrying on the unknown quantum information is then combined with one particle of the entangled states for Bell-state measurements, which leads to a transfer of the original quantum information onto the other particle of the entangled states. However in most of the implemented teleportation experiments nowadays, the Bell-state measurements are performed even before successful distribution of entanglement. This leads to an instant collapse of the quantum state for the transmitted particle, which is actually a single-particle transmission thereafter. Thus the true distance for quantum teleportation is, in fact, only in a level of meters. In the present experiment we design a novel scheme which has overcome this limit by utilizing fiber as quantum memory. A complete quantum teleportation is achieved upon successful entanglement distribution over 967 meters in public free space. Active feed-forward control techniques are developed for real-time transfer of quantum information. The overall experimental fidelities for teleported states are better than 89.6%, which signify high-quality teleportation.

  4. OncoBinder facilitates interpretation of proteomic interaction data by capturing coactivation pairs in cancer.

    PubMed

    Van Coillie, Samya; Liang, Lunxi; Zhang, Yao; Wang, Huanbin; Fang, Jing-Yuan; Xu, Jie

    2016-04-05

    High-throughput methods such as co-immunoprecipitationmass spectrometry (coIP-MS) and yeast 2 hybridization (Y2H) have suggested a broad range of unannotated protein-protein interactions (PPIs), and interpretation of these PPIs remains a challenging task. The advancements in cancer genomic researches allow for the inference of "coactivation pairs" in cancer, which may facilitate the identification of PPIs involved in cancer. Here we present OncoBinder as a tool for the assessment of proteomic interaction data based on the functional synergy of oncoproteins in cancer. This decision tree-based method combines gene mutation, copy number and mRNA expression information to infer the functional status of protein-coding genes. We applied OncoBinder to evaluate the potential binders of EGFR and ERK2 proteins based on the gastric cancer dataset of The Cancer Genome Atlas (TCGA). As a result, OncoBinder identified high confidence interactions (annotated by Kyoto Encyclopedia of Genes and Genomes (KEGG) or validated by low-throughput assays) more efficiently than co-expression based method. Taken together, our results suggest that evaluation of gene functional synergy in cancer may facilitate the interpretation of proteomic interaction data. The OncoBinder toolbox for Matlab is freely accessible online.

  5. Functional Behavioral Assessment: An Interactive Training Module. User's Manual & Facilitator's Guide. Second Edition.

    ERIC Educational Resources Information Center

    Liaupsin, Carl J.; Scott, Terry M.; Nelson, C. Michael

    This user's manual and facilitator's guide is intended for use with an accompanying interactive CD-ROM to provide a complete training program in conducting functional behavioral assessments (FBAs) as required under the 1997 reauthorization of the Individuals with Disabilities Education Act. Chapter 1 provides general information for users, such as…

  6. Facilitated citrate-dependent iron translocation increases rice endosperm iron and zinc concentrations.

    PubMed

    Wu, Ting-Ying; Gruissem, Wilhelm; Bhullar, Navreet K

    2018-05-01

    Iron deficiency affects one third of the world population. Most iron biofortification strategies have focused on genes involved in iron uptake and storage but facilitating internal long-distance iron translocation has been understudied for increasing grain iron concentrations. Citrate is a primary iron chelator, and the transporter FERRIC REDUCTASE DEFECTIVE 3 (FRD3) loads citrate into the xylem. We have expressed AtFRD3 in combination with AtNAS1 (NICOTIANAMINE SYNTHASE 1) and PvFER (FERRITIN) or with PvFER alone to facilitate long-distance iron transport together with efficient iron uptake and storage in the rice endosperm. The citrate and iron concentrations in the xylem sap of transgenic plants increased two-fold compared to control plants. Iron and zinc levels increased significantly in polished and unpolished rice grains to more than 70% of the recommended estimated average requirement (EAR) for iron and 140% of the recommended EAR for zinc in polished rice grains. Furthermore, the transformed lines showed normal phenotypic growth, were tolerant to iron deficiency and aluminum toxicity, and had grain cadmium levels similar to control plants. Together, our results demonstrate that deploying FRD for iron biofortification has no obvious anti-nutritive effects and should be considered as an effective strategy for reducing human iron deficiency anemia. Copyright © 2018 The Authors. Published by Elsevier B.V. All rights reserved.

  7. Two-Photon Excitation in Biological Material for Conventional and Long Working-Distance Objectives.

    NASA Astrophysics Data System (ADS)

    Keeler, W. J.; McGhee, P.

    2000-03-01

    The application of laser two-photon excitation or nonlinear second-harmonic generation to imaging, spectroscopy, and light activated medical therapies, is an expanding field of research. When small feature sizes such as cells and their components are to be studied, high numerical aperture (NA) lenses are required to obtain the necessary lateral and axial resolutions. If one wishes to increase the depth of sample penetration, factors such as scattering and absorption quickly degrade the quality of the focused beam. The problem is further exacerbated by the short working distance of conventional high NA microscope objectives if they are used for light delivery and pickup. These lenses and their accompanying eyepieces, are designed to produce an exit pupil that can be accomodated by the human eye. Such a design will underfil detectors such as large CCD arrays. To simultaneously increase the working distance at the sample and the system exit pupil, larger scale objectives can be used. We will report the results of two-photon excitation and fluorescence investigations of several feature sizes as a function of penetration depth in homogeneous media and tissue samples, for conventional and long working distance objectives. The possible implications of these results to imaging and therapeutic dose delivery will also be presented.

  8. The requirement for enhanced CREB1 expression in consolidation of long-term synaptic facilitation and long-term excitability in sensory neurons of Aplysia

    PubMed Central

    Liu, Rong-Yu; Cleary, Leonard J.; Byrne, John H.

    2011-01-01

    Accumulating evidence suggests that the transcriptional activator CREB1 is important for serotonin (5-HT)-induced long-term facilitation (LTF) of the sensorimotor synapse in Aplysia. Moreover, creb1 is among the genes activated by CREB1, suggesting a role for this protein beyond the induction phase of LTF. The time course of the requirement for CREB1 synthesis in the consolidation of long-term facilitation was examined using RNA interference (RNAi) techniques in sensorimotor co-cultures. Injection of CREB1 small-interfering RNA (siRNA) immediately or 10 h after 5-HT treatment blocked LTF when measured at 24 h and 48 h after treatment. In contrast, CREB1 siRNA did not block LTF when injected 16 h after 5-HT treatment. These results demonstrate that creb1 expression must be sustained for a relatively long time in order to support the consolidation of LTF. In addition, LTF is also accompanied by a long-term increase in the excitability (LTE) of sensory neurons (SNs). Because LTE was observed in the isolated SN after 5-HT treatment, this long-term change was intrinsic to that element of the circuit. LTE was blocked when CREB1 siRNA was injected into isolated SNs immediately after 5-HT treatment. These data suggest that 5-HT-induced CREB1 synthesis is required for consolidation of both LTF and LTE. PMID:21543617

  9. The Australian Bogong Moth Agrotis infusa: A Long-Distance Nocturnal Navigator

    PubMed Central

    Warrant, Eric; Frost, Barrie; Green, Ken; Mouritsen, Henrik; Dreyer, David; Adden, Andrea; Brauburger, Kristina; Heinze, Stanley

    2016-01-01

    The nocturnal Bogong moth (Agrotis infusa) is an iconic and well-known Australian insect that is also a remarkable nocturnal navigator. Like the Monarch butterflies of North America, Bogong moths make a yearly migration over enormous distances, from southern Queensland, western and northwestern New South Wales (NSW) and western Victoria, to the alpine regions of NSW and Victoria. After emerging from their pupae in early spring, adult Bogong moths embark on a long nocturnal journey towards the Australian Alps, a journey that can take many days or even weeks and cover over 1000 km. Once in the Alps (from the end of September), Bogong moths seek out the shelter of selected and isolated high ridge-top caves and rock crevices (typically at elevations above 1800 m). In hundreds of thousands, moths line the interior walls of these cool alpine caves where they “hibernate” over the summer months (referred to as “estivation”). Towards the end of the summer (February and March), the same individuals that arrived months earlier leave the caves and begin their long return trip to their breeding grounds. Once there, moths mate, lay eggs and die. The moths that hatch in the following spring then repeat the migratory cycle afresh. Despite having had no previous experience of the migratory route, these moths find their way to the Alps and locate their estivation caves that are dotted along the high alpine ridges of southeastern Australia. How naïve moths manage this remarkable migratory feat still remains a mystery, although there are many potential sensory cues along the migratory route that moths might rely on during their journey, including visual, olfactory, mechanical and magnetic cues. Here we review our current knowledge of the Bogong moth, including its natural history, its ecology, its cultural importance to the Australian Aborigines and what we understand about the sensory basis of its long-distance nocturnal migration. From this analysis it becomes clear that

  10. The benefits of sensorimotor knowledge: body-object interaction facilitates semantic processing.

    PubMed

    Siakaluk, Paul D; Pexman, Penny M; Sears, Christopher R; Wilson, Kim; Locheed, Keri; Owen, William J

    2008-04-05

    This article examined the effects of body-object interaction (BOI) on semantic processing. BOI measures perceptions of the ease with which a human body can physically interact with a word's referent. In Experiment 1, BOI effects were examined in 2 semantic categorization tasks (SCT) in which participants decided if words are easily imageable. Responses were faster and more accurate for high BOI words (e.g., mask) than for low BOI words (e.g., ship). In Experiment 2, BOI effects were examined in a semantic lexical decision task (SLDT), which taps both semantic feedback and semantic processing. The BOI effect was larger in the SLDT than in the SCT, suggesting that BOI facilitates both semantic feedback and semantic processing. The findings are consistent with the embodied cognition perspective (e.g., Barsalou's, 1999, Perceptual Symbols Theory), which proposes that sensorimotor interactions with the environment are incorporated in semantic knowledge. 2008 Cognitive Science Society, Inc.

  11. X-ray beam transfer between hollow fibers for long-distance transport

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tanaka, Yoshihito, E-mail: tanaka@sci.u-hyogo.ac.jp; Matsushita, Ryuki; Shiraishi, Ryutaro

    2016-07-27

    Fiber optics for controlling the x-ray beam trajectory has been examined at the synchrotron facility of SPring-8. Up to now, we have achieved beam deflection by several tens of milli-radian and axis shift of around 75 mm with a 1.5 m-long flexible hollow glass capillary. The achievable beam deflecting angle, axis shift, and timing delay are, in principle, proportional to the length, the square of length and the cube of length, respectively. Thus, for further applications, requiring larger beam shift and pulse delay, longer fibers are indispensable. In order to achieve long-distance transport using the fiber, we thus examined themore » connection transferring x-rays between fibers in an experimental hutch. The acceptance angle at the input end and the throughput efficiency of the second fiber is consistent with the consideration of the output beam divergence of the first fiber. The enhancement of the transfer efficiency is also discussed for the cases of a closer joint and the use of a refractive lens as a coupler.« less

  12. Silicon quantum processor with robust long-distance qubit couplings

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tosi, Guilherme; Mohiyaddin, Fahd A.; Schmitt, Vivien

    Practical quantum computers require a large network of highly coherent qubits, interconnected in a design robust against errors. Donor spins in silicon provide state-of-the-art coherence and quantum gate fidelities, in a platform adapted from industrial semiconductor processing. Here we present a scalable design for a silicon quantum processor that does not require precise donor placement and leaves ample space for the routing of interconnects and readout devices. We introduce the flip-flop qubit, a combination of the electron-nuclear spin states of a phosphorus donor that can be controlled by microwave electric fields. Two-qubit gates exploit a second-order electric dipole-dipole interaction, allowingmore » selective coupling beyond the nearest-neighbor, at separations of hundreds of nanometers, while microwave resonators can extend the entanglement to macroscopic distances. We predict gate fidelities within fault-tolerance thresholds using realistic noise models. This design provides a realizable blueprint for scalable spin-based quantum computers in silicon.« less

  13. Chromosome3D: reconstructing three-dimensional chromosomal structures from Hi-C interaction frequency data using distance geometry simulated annealing.

    PubMed

    Adhikari, Badri; Trieu, Tuan; Cheng, Jianlin

    2016-11-07

    Reconstructing three-dimensional structures of chromosomes is useful for visualizing their shapes in a cell and interpreting their function. In this work, we reconstruct chromosomal structures from Hi-C data by translating contact counts in Hi-C data into Euclidean distances between chromosomal regions and then satisfying these distances using a structure reconstruction method rigorously tested in the field of protein structure determination. We first evaluate the robustness of the overall reconstruction algorithm on noisy simulated data at various levels of noise by comparing with some of the state-of-the-art reconstruction methods. Then, using simulated data, we validate that Spearman's rank correlation coefficient between pairwise distances in the reconstructed chromosomal structures and the experimental chromosomal contact counts can be used to find optimum conversion rules for transforming interaction frequencies to wish distances. This strategy is then applied to real Hi-C data at chromosome level for optimal transformation of interaction frequencies to wish distances and for ranking and selecting structures. The chromosomal structures reconstructed from a real-world human Hi-C dataset by our method were validated by the known two-compartment feature of the human chromosome organization. We also show that our method is robust with respect to the change of the granularity of Hi-C data, and consistently produces similar structures at different chromosomal resolutions. Chromosome3D is a robust method of reconstructing chromosome three-dimensional models using distance restraints obtained from Hi-C interaction frequency data. It is available as a web application and as an open source tool at http://sysbio.rnet.missouri.edu/chromosome3d/ .

  14. Ecological specialization to fluctuating resources prevents long-distance migratory raptors from becoming sedentary on islands.

    PubMed

    Gangoso, Laura; López-López, Pascual; Grande, Juan Manuel; Mellone, Ugo; Limiñana, Rubén; Urios, Vicente; Ferrer, Miguel

    2013-01-01

    The adaptive transition between behavioral strategies, such as the shift from migratoriness to sedentariness, remains an outstanding question in evolutionary ecology. Density-dependent variation in the age of first breeding has been proposed as a feasible mechanism through which long-lived migratory birds with deferred sexual maturity should become sedentary to persist on islands. Although this pattern seems to hold for most raptors and herons, a few exceptions have been identified. One of these exceptions is the Eleonora's falcon, a long-distance migratory bird, which shows one of the most peculiar adaptations in the timing of reproduction and food requirements among raptors. Here, we compiled data concerning demography, banding recoveries and satellite tracking of Eleonora's falcons to discuss likely explanations for the exceptional behavior of this insular long-distance migratory species. New data reveal that Eleonora's falcons do return to the natal colonies in their first year and young birds are able to breed. However, in contrast to previous hypothesis, the highly specialized strategy of this and other ecologically similar species, as well as the virtual lack of food during winter at breeding areas prevent them from becoming sedentary on islands. Although the ultimate mechanisms underlying the process of sedentarization remain poorly understood, the evidence provided reveal the existence of important trade-offs associated with ecological specialization that may become particularly relevant in the present context of global change.

  15. Thermal Windows on Brazilian Free-tailed Bats Facilitate Thermoregulation during Prolonged Flight

    PubMed Central

    Reichard, Jonathan D.; Prajapati, Suresh I.; Austad, Steven N.; Keller, Charles; Kunz, Thomas H.

    2010-01-01

    The Brazilian free-tailed bat (Tadarida brasiliensis) experiences challenging thermal conditions while roosting in hot caves, flying during warm daylight conditions, and foraging at cool high altitudes. Using thermal infrared cameras, we identified hot spots along the flanks of free-ranging Brazilian free-tailed bats, ventral to the extended wings. These hot spots are absent in syntopic cave myotis (Myotis velifer), a species that forages over relatively short distances, and does not engage in long-distance migration. We hypothesized that the hot spots, or “radiators,” on Brazilian free-tailed bats may be adaptations for migration, particularly in this long-distance, high-flying species. We examined the vasculature of radiators on Brazilian free-tailed bats with transillumination to characterize the unique arrangements of arteries and veins that are positioned perpendicular to the body in the proximal region of the wing. We hypothesized that these radiators aid in maintaining heat balance by flushing the uninsulated thermal window with warm blood, thereby dissipating heat while bats are flying under warm conditions, but shunting blood away and conserving heat when they are flying in cooler air at high altitudes. We also examined fluid-preserved specimens representing 122 species from 15 of 18 chiropteran families and radiators appeared present only in species in the family Molossidae, including both sedentary and migratory species and subspecies. Thus, the radiator appears to be a unique trait that may facilitate energy balance and water balance during sustained dispersal, foraging, and long-distance migration. PMID:20811514

  16. Analysis of swimming performance in FINA World Cup long-distance open water races

    PubMed Central

    2014-01-01

    Background Age and peak performance in ultra-endurance athletes have been mainly investigated in long-distance runners and triathletes, but not for long-distance swimmers. The present study investigated the age and swimming performance of elite ultra-distance swimmers competing in the 5-, 10- and 25-km Fédération Internationale de Natation (FINA) World Cup swimming events. Methods The associations of age and swimming speed in elite male and female swimmers competing in World Cup events of 5-, 10- and 25-km events from 2000 to 2012 were analysed using single and multi-level regression analyses. Results During the studied period, the swimming speed of the annual top ten women decreased significantly from 4.94 ± 0.20 to 4.77 ± 0.09 km/h in 5 km and from 4.60 ± 0.04 to 4.44 ± 0.08 km/h in 25 km, while it significantly increased from 4.57 ± 0.01 to 5.75 ± 0.01 km/h in 10 km. For the annual top ten men, peak swimming speed decreased significantly from 5.42 ± 0.04 to 5.39 ± 0.02 km/h in 5 km, while it remained unchanged at 5.03 ± 0.32 km/h in 10 km and at 4.94 ± 0.35 km/h in 25 km. The age of peak swimming speed for the annual top ten women remained stable at 22.5 ± 1.2 years in 5 km, at 23.4 ± 0.9 years in 10 km and at 23.8 ± 0.9 years in 25 km. For the annual top ten men, the age of peak swimming speed increased from 23.7 ± 2.8 to 28.0 ± 5.1 years in 10 km but remained stable at 24.8 ± 1.0 years in 5 km and at 27.2 ± 1.1 years in 25 km. Conclusion Female long-distance swimmers competing in FINA World Cup races between 2000 and 2012 improved in 10 km but impaired in 5 and 25 km, whereas men only impaired in 5 km. The age of peak performance was younger in women (approximately 23 years) compared to men (about 25–27 years). PMID:24382200

  17. Facilitation among plants in alpine environments in the face of climate change.

    PubMed

    Anthelme, Fabien; Cavieres, Lohengrin A; Dangles, Olivier

    2014-01-01

    While there is a large consensus that plant-plant interactions are a crucial component of the response of plant communities to the effects of climate change, available data remain scarce, particularly in alpine systems. This represents an important obstacle to making consistent predictions about the future of plant communities. Here, we review current knowledge on the effects of climate change on facilitation among alpine plant communities and propose directions for future research. In established alpine communities, while warming seemingly generates a net facilitation release, earlier snowmelt may increase facilitation. Some nurse plants are able to buffer microenvironmental changes in the long term and may ensure the persistence of other alpine plants through local migration events. For communities migrating to higher elevations, facilitation should play an important role in their reorganization because of the harsher environmental conditions. In particular, the absence of efficient nurse plants might slow down upward migration, possibly generating chains of extinction. Facilitation-climate change relationships are expected to shift along latitudinal gradients because (1) the magnitude of warming is predicted to vary along these gradients, and (2) alpine environments are significantly different at low vs. high latitudes. Data on these expected patterns are preliminary and thus need to be tested with further studies on facilitation among plants in alpine environments that have thus far not been considered. From a methodological standpoint, future studies will benefit from the spatial representation of the microclimatic environment of plants to predict their response to climate change. Moreover, the acquisition of long-term data on the dynamics of plant-plant interactions, either through permanent plots or chronosequences of glacial recession, may represent powerful approaches to clarify the relationship between plant interactions and climate change.

  18. Supporting Distance Learners for Collaborative Problem Solving.

    ERIC Educational Resources Information Center

    Verdejo, M. F.; Barros, B.; Abad, M. T.

    This paper describes a computer-supported environment designed to facilitate distance learning through collaborative problem-solving. The goal is to encourage distance learning students to work together, in order to promote both learning of collaboration and learning through collaboration. Collaboration is defined as working together on a common…

  19. Climatic conditions produce contrasting influences on demographic traits in a long-distance Arctic migrant.

    PubMed

    Cleasby, Ian R; Bodey, Thomas W; Vigfusdottir, Freydis; McDonald, Jenni L; McElwaine, Graham; Mackie, Kerry; Colhoun, Kendrew; Bearhop, Stuart

    2017-03-01

    The manner in which patterns of variation and interactions among demographic rates contribute to population growth rate (λ) is key to understanding how animal populations will respond to changing climatic conditions. Migratory species are likely to be particularly sensitive to climatic conditions as they experience a range of different environments throughout their annual cycle. However, few studies have provided fully integrated demographic analyses of migratory populations in response to changing climatic conditions. Here, we employed integrated population models to demonstrate that the environmental conditions experienced during a short but critical period play a central role in the demography of a long-distance migrant, the light-bellied Brent goose (Branta bernicla hrota). Female survival was positively associated with June North Atlantic Oscillation (NAO) values, whereas male survival was not. In contrast, breeding productivity was negatively associated with June NAO, suggesting a trade-off between female survival and reproductive success. Both adult female and adult male survival showed low temporal variation, whereas there was high temporal variation in recruitment and breeding productivity. In addition, while annual population growth was positively correlated with annual breeding productivity, a sensitivity analysis revealed that population growth was most sensitive to changes in adult survival. Our results demonstrate that the environmental conditions experienced during a relatively short-time window at the start of the breeding season play a critical role in shaping the demography of a long-distant Arctic migrant. Crucially, different demographic rates responded in opposing directions to climatic variation, emphasising the need for integrated analysis of multiple demographic traits when understanding population dynamics. © 2016 The Authors. Journal of Animal Ecology © 2016 British Ecological Society.

  20. A new passive system for contamination-free long-distance cryo-transfer of biological tissues

    NASA Astrophysics Data System (ADS)

    Cheng, Tian; Plane, Florent; Søgaard Jensen, Louise Helene; van den Brandt, Ben; Comment, Arnaud; Meibom, Anders

    2017-12-01

    Several new analytical techniques require long-distance cryogenic transfer of samples that need to be kept at stable temperatures for long time periods, but also to be additionally contamination-free. In this study we developed a passive transfer system to fulfil those requirements. With 125mL of liquid nitrogen stored, one cryo-sectioned sample was maintained around 120±1 K and a pressure of about 3x10-7 mbar for at least 2 hours. With a total transfer weight of 5 Kg this system can be easily handled and carried by any transportation means so that the same sample can be used for different imaging centres located remotely permitting correlative studies.

  1. Integration of Biosynthesis and Long-Distance Transport Establish Organ-Specific Glucosinolate Profiles in Vegetative Arabidopsis[W

    PubMed Central

    Andersen, Tonni Grube; Nour-Eldin, Hussam Hassan; Fuller, Victoria Louise; Olsen, Carl Erik; Burow, Meike; Halkier, Barbara Ann

    2013-01-01

    Although it is essential for plant survival to synthesize and transport defense compounds, little is known about the coordination of these processes. Here, we investigate the above- and belowground source-sink relationship of the defense compounds glucosinolates in vegetative Arabidopsis thaliana. In vivo feeding experiments demonstrate that the glucosinolate transporters1 and 2 (GTR1 and GTR2), which are essential for accumulation of glucosinolates in seeds, are likely to also be involved in bidirectional distribution of glucosinolates between the roots and rosettes, indicating phloem and xylem as their transport pathways. Grafting of wild-type, biosynthetic, and transport mutants show that both the rosette and roots are able to synthesize aliphatic and indole glucosinolates. While rosettes constitute the major source and storage site for short-chained aliphatic glucosinolates, long-chained aliphatic glucosinolates are synthesized both in roots and rosettes with roots as the major storage site. Our grafting experiments thus indicate that in vegetative Arabidopsis, GTR1 and GTR2 are involved in bidirectional long-distance transport of aliphatic but not indole glucosinolates. Our data further suggest that the distinct rosette and root glucosinolate profiles in Arabidopsis are shaped by long-distance transport and spatially separated biosynthesis, suggesting that integration of these processes is critical for plant fitness in complex natural environments. PMID:23995084

  2. An Observational Study on Quantifying the Distance of Supercell-Boundary Interaction in the Great Plains

    NASA Astrophysics Data System (ADS)

    Magee, Kathleen Marie

    strength. The distance of different report types near the same boundary surprisingly did not test as statistically different, except for warm fronts; however, when comparing the distances of the same report type associated with different boundaries, statistically significant differences were found for different boundaries in which different report types are maximally produced. Temperature gradients are not as statistically different between boundaries, but the temperature gradient within the same boundary is statistically significant for the occurrence of tornadoes vs. hail. Additional analyses were conducted to complement the distributions of severe report distances. Previous research has demonstrated that the angle at which supercells interact with boundaries impacts tornado production; in the present dataset, supercells interacting at an angle less than 45° are not only more likely to produce tornadoes, but also more likely to produce significantly severe tornadoes. Additionally, other studies have suggested that the temperature gradient of a boundary is of minimal importance with regards to tornado production. Interestingly, the tornadoes in this study were associated with stronger temperature gradients than for hail or wind production, thus v implying that a stronger amount of baroclinically-generated horizontal vorticity is required for tornadogenesis, likely due to the enhanced low-level rotation.

  3. The association between plantar heel pain and running surfaces in competitive long-distance male runners.

    PubMed

    Hotta, Takayuki; Nishiguchi, Shu; Fukutani, Naoto; Tashiro, Yuto; Adachi, Daiki; Morino, Saori; Aoyama, Tomoki

    2016-09-01

    Plantar heel pain (PHP) is a common complaint, and is most often caused by plantar fasciitis. Plantar fasciitis is reported to be associated with running surfaces, however the association between PHP and running surfaces has not previously been revealed in an epidemiological investigation. Therefore, the purpose of the current study was to examine the association between PHP and running surfaces. This is a cross-sectional study. A total of 347 competitive long-distance male runners participated in this study. The participants completed an original questionnaire, which included items assessing demographic characteristics, training characteristics focusing on running surfaces (soft surface, hard surface and tartan), and the prevalence of PHP during the previous 12 months. A logistic regression analysis was used to identify the effect of running surfaces on PHP. We found that 21.9% of participants had experienced PHP during the previous 12 months. The multivariate logistic regression analysis, after adjusting for demographic and training characteristics, revealed that running on tartan was associated with PHP (odds ratio 2.82, 95% confidence interval 1.42 to 5.61; P<0.01). Our findings suggest that running more than 25% on tartan is associated with PHP in competitive long-distance male runners.

  4. How the definition of acceptable antigens and epitope analysis can facilitate transplantation of highly sensitized patients with excellent long-term graft survival.

    PubMed

    Heidt, Sebastiaan; Haasnoot, Geert W; Claas, Frans H J

    2018-05-24

    Highly sensitized patients awaiting a renal transplant have a low chance of receiving an organ offer. Defining acceptable antigens and using this information for allocation purposes can vastly enhance transplantation of this subgroup of patients, which is the essence of the Eurotransplant Acceptable Mismatch program. Acceptable antigens can be determined by extensive laboratory testing, as well as on basis of human leukocyte antigen (HLA) epitope analyses. Within the Acceptable Mismatch program, there is no effect of HLA mismatches on long-term graft survival. Furthermore, patients transplanted through the Acceptable Mismatch program have similar long-term graft survival to nonsensitized patients transplanted through regular allocation. Although HLA epitope analysis is already being used for defining acceptable HLA antigens for highly sensitized patients in the Acceptable Mismatch program, increasing knowledge on HLA antibody - epitope interactions will pave the way toward the definition of acceptable epitopes for highly sensitized patients in the future. Allocation based on acceptable antigens can facilitate transplantation of highly sensitized patients with excellent long-term graft survival.

  5. Long-distance transmission of light in a scintillator-based radiation detector

    DOEpatents

    Dowell, Jonathan L.; Talbott, Dale V.; Hehlen, Markus P.

    2017-07-11

    Scintillator-based radiation detectors capable of transmitting light indicating the presence of radiation for long distances are disclosed herein. A radiation detector can include a scintillator layer and a light-guide layer. The scintillator layer is configured to produce light upon receiving incident radiation. The light-guide layer is configured to receive light produced by the scintillator layer and either propagate the received light through the radiation detector or absorb the received light and emit light, through fluorescence, that is propagated through the radiation detector. A radiation detector can also include an outer layer partially surrounding the scintillator layer and light-guide layer. The index of refraction of the light-guide layer can be greater than the index of refraction of adjacent layers.

  6. Body temperature change and outcomes in patients undergoing long-distance air medical transport.

    PubMed

    Nakajima, Mikio; Aso, Shotaro; Yasunaga, Hideo; Shirokawa, Masamitsu; Nakano, Tomotsugu; Miyakuni, Yasuhiko; Goto, Hideaki; Yamaguchi, Yoshihiro

    2018-04-30

    Short-distance air medical transport for adult emergency patients does not significantly affect patients' body temperature and outcomes. This study aimed to examine the influence of long-distance air medical transport on patients' body temperatures and the relationship between body temperature change and mortality. We retrospectively enrolled consecutive patients transferred via helicopter or plane from isolated islands to an emergency medical center in Tokyo, Japan between April 2010 and December 2016. Patients' average body temperature was compared before and after air transport using a paired t-test, and corrections between body temperature change and flight duration were calculated using Pearson's correlation coefficient. Multivariable logistic regression models were then used to examine the association between body temperature change and in-hospital mortality. Of 1253 patients, the median age was 72 years (interquartile range, 60-82 years) and median flight duration was 71 min (interquartile range, 54-93 min). In-hospital mortality was 8.5%, and average body temperature was significantly different before and after air transport (36.7 °C versus 36.3 °C; difference: -0.36 °C; 95% confidence interval, -0.30 to -0.42; p < 0.001). There was no correlation between body temperature change and flight duration (r = 0.025, p = 0.371). In-hospital death was significantly associated with (i) hyperthermia (>38.0 °C) or normothermia (36.0-37.9 °C) before air transport and hypothermia after air transport (odds ratio, 2.08; 95% confidence interval, 1.20-3.63; p = 0.009), and (ii) winter season (odds ratio, 2.15; 95% confidence interval, 1.08-4.27; p = 0.030). Physicians should consider body temperature change during long-distance air transport in patients with not only hypothermia but also normothermia or hyperthermia before air transport, especially in winter. Copyright © 2018 Elsevier Inc. All rights reserved.

  7. Locating the Source of Long-Distance Radio Distress Signals from the Southern Ocean

    DTIC Science & Technology

    1988-03-01

    fomZwaic ad e(91) Ref t ~) areshown -39 - ERL-0449-SD 30 EQU IV ALE N T GEOGRAPHIC LATITUDE (DEG), S. j ~jj5"f RN HEMISPHERE, AT LONGITUDE OF ADELAIDE...45 - ERL-0449-SD AST = 48 ASB = 61 - 0.5(Kp - i) ANB = 73 - 1.0(Kp- ) ANT = 76 - 1.25(Kp - j ) where A represents invariant latitude, the subscripts T ...frequency (MF) maritime band (410-512 kHz) for long-distance commun- cation in telegraphy (Morse code) at a frequency which was returned t the earth by

  8. Enriched Open Field Facilitates Exercise and Social Interaction in 2 Strains of Guinea Pigs (Cavia porcellus)

    PubMed Central

    Brewer, Jacob S; Bellinger, Seanceray A; Joshi, Prianca; Kleven, Gale A

    2014-01-01

    Current housing guidelines for laboratory rodents include recommendations for enrichment. Working with guinea pigs, we have developed an open-field enrichment paradigm that provides several aspects of this species’ natural environment. These naturalistic aspects include access to increased space for exploration, access to western timothy (Phleum pratense L.) hay, and grouping as a herd to facilitate social interaction. To determine the immediate effect on behavior from access to the enriched environment, female guinea pigs from 2 strains, IAF Hairless and NIH Hartley, were observed in both standard home cages and an open-field enriched environment. Subjects were housed with cagemates in pairs for the home-cage observation and were grouped as a herd when in the open-field arena. Behaviors were videorecorded for 1 h and then scored. Salivary cortisol levels were measured both prior to and immediately after behavioral observations. Analyses revealed higher levels of activity and social interaction in the open-field arena compared with the home cage, with no significant change in salivary cortisol levels. These results suggest that exposure to the open-field environment provide increased opportunities for exercise and social enrichment. Although additional studies are needed to determine long-term effects on experimental outcomes, the open-field configuration holds promise as a laboratory enrichment paradigm for guinea pigs. PMID:25199089

  9. Enriched open field facilitates exercise and social interaction in 2 strains of guinea pigs (Cavia porcellus).

    PubMed

    Brewer, Jacob S; Bellinger, Seanceray A; Joshi, Prianca; Kleven, Gale A

    2014-07-01

    Current housing guidelines for laboratory rodents include recommendations for enrichment. Working with guinea pigs, we have developed an open-field enrichment paradigm that provides several aspects of this species' natural environment. These naturalistic aspects include access to increased space for exploration, access to western timothy (Phleum pratense L.) hay, and grouping as a herd to facilitate social interaction. To determine the immediate effect on behavior from access to the enriched environment, female guinea pigs from 2 strains, IAF Hairless and NIH Hartley, were observed in both standard home cages and an open-field enriched environment. Subjects were housed with cagemates in pairs for the home-cage observation and were grouped as a herd when in the open-field arena. Behaviors were videorecorded for 1 h and then scored. Salivary cortisol levels were measured both prior to and immediately after behavioral observations. Analyses revealed higher levels of activity and social interaction in the open-field arena compared with the home cage, with no significant change in salivary cortisol levels. These results suggest that exposure to the open-field environment provide increased opportunities for exercise and social enrichment. Although additional studies are needed to determine long-term effects on experimental outcomes, the open-field configuration holds promise as a laboratory enrichment paradigm for guinea pigs.

  10. Epidemic spreading in networks with nonrandom long-range interactions.

    PubMed

    Estrada, Ernesto; Kalala-Mutombo, Franck; Valverde-Colmeiro, Alba

    2011-09-01

    An "infection," understood here in a very broad sense, can be propagated through the network of social contacts among individuals. These social contacts include both "close" contacts and "casual" encounters among individuals in transport, leisure, shopping, etc. Knowing the first through the study of the social networks is not a difficult task, but having a clear picture of the network of casual contacts is a very hard problem in a society of increasing mobility. Here we assume, on the basis of several pieces of empirical evidence, that the casual contacts between two individuals are a function of their social distance in the network of close contacts. Then, we assume that we know the network of close contacts and infer the casual encounters by means of nonrandom long-range (LR) interactions determined by the social proximity of the two individuals. This approach is then implemented in a susceptible-infected-susceptible (SIS) model accounting for the spread of infections in complex networks. A parameter called "conductance" controls the feasibility of those casual encounters. In a zero conductance network only contagion through close contacts is allowed. As the conductance increases the probability of having casual encounters also increases. We show here that as the conductance parameter increases, the rate of propagation increases dramatically and the infection is less likely to die out. This increment is particularly marked in networks with scale-free degree distributions, where infections easily become epidemics. Our model provides a general framework for studying epidemic spreading in networks with arbitrary topology with and without casual contacts accounted for by means of LR interactions.

  11. Autofocusing Airy beam STED microscopy with long focal distance

    NASA Astrophysics Data System (ADS)

    Hu, Di; Liang, Yao; Chen, Yin; Chen, Zan Hui; Huang, Xu Guang

    2017-12-01

    Stimulated emission depletion (STED) is a very important technique in super-resolution microscopy. Until now, while autofocusing Airy beam (AAB) has been an attractive theme for both theoretical and applied researches, there are almost no report on AABs being used in STED microscopy. In this paper, we propose a novel STED microscopy based on AABs. A radially symmetric 3/2 phase plate is involved to simultaneously generate autofocusing excitation- and depletion-Airy beams. Remarkably, the AAB can auto-focus to a wavelength-scale spot with a long focal depth (several millimeters): on the contrary, the working distance of a conventional high numerical aperture (NA) objective is usually very short (about 200 μm). Our calculations indicate that the AAB based STED microscopy can achieve a super-resolution spot with FWHM of 58 nm while the focal length is 4.638 mm. Moreover, with properties of non-diffracting and self-healing, the Airy beam could enable a reduction of the scattering distortion induced by the specimens and has a great potential in imaging thick specimens.

  12. Super-Coulombic atom–atom interactions in hyperbolic media

    PubMed Central

    Cortes, Cristian L.; Jacob, Zubin

    2017-01-01

    Dipole–dipole interactions, which govern phenomena such as cooperative Lamb shifts, superradiant decay rates, Van der Waals forces and resonance energy transfer rates, are conventionally limited to the Coulombic near-field. Here we reveal a class of real-photon and virtual-photon long-range quantum electrodynamic interactions that have a singularity in media with hyperbolic dispersion. The singularity in the dipole–dipole coupling, referred to as a super-Coulombic interaction, is a result of an effective interaction distance that goes to zero in the ideal limit irrespective of the physical distance. We investigate the entire landscape of atom–atom interactions in hyperbolic media confirming the giant long-range enhancement. We also propose multiple experimental platforms to verify our predicted effect with phonon–polaritonic hexagonal boron nitride, plasmonic super-lattices and hyperbolic meta-surfaces as well. Our work paves the way for the control of cold atoms above hyperbolic meta-surfaces and the study of many-body physics with hyperbolic media. PMID:28120826

  13. Super-Coulombic atom-atom interactions in hyperbolic media

    NASA Astrophysics Data System (ADS)

    Cortes, Cristian L.; Jacob, Zubin

    2017-01-01

    Dipole-dipole interactions, which govern phenomena such as cooperative Lamb shifts, superradiant decay rates, Van der Waals forces and resonance energy transfer rates, are conventionally limited to the Coulombic near-field. Here we reveal a class of real-photon and virtual-photon long-range quantum electrodynamic interactions that have a singularity in media with hyperbolic dispersion. The singularity in the dipole-dipole coupling, referred to as a super-Coulombic interaction, is a result of an effective interaction distance that goes to zero in the ideal limit irrespective of the physical distance. We investigate the entire landscape of atom-atom interactions in hyperbolic media confirming the giant long-range enhancement. We also propose multiple experimental platforms to verify our predicted effect with phonon-polaritonic hexagonal boron nitride, plasmonic super-lattices and hyperbolic meta-surfaces as well. Our work paves the way for the control of cold atoms above hyperbolic meta-surfaces and the study of many-body physics with hyperbolic media.

  14. Storage and long-distance distribution of telecommunications-band polarization entanglement generated in an optical fiber.

    PubMed

    Li, Xiaoying; Voss, Paul L; Chen, Jun; Sharping, Jay E; Kumar, Prem

    2005-05-15

    We demonstrate storage of polarization-entangled photons for 125 micros, a record storage time to date, in a 25-km-long fiber spool, using a telecommunications-band fiber-based source of entanglement. With this source we also demonstrate distribution of polarization entanglement over 50 km by separating the two photons of an entangled pair and transmitting them individually over separate 25-km fibers. The measured two-photon fringe visibilities were 82% in the storage experiment and 86% in the distribution experiment. Preservation of polarization entanglement over such long-distance transmission demonstrates the viability of all-fiber sources for use in quantum memories and quantum logic gates.

  15. Physiological Response to Facial Expressions in Peripersonal Space Determines Interpersonal Distance in a Social Interaction Context.

    PubMed

    Cartaud, Alice; Ruggiero, Gennaro; Ott, Laurent; Iachini, Tina; Coello, Yann

    2018-01-01

    Accurate control of interpersonal distances in social contexts is an important determinant of effective social interactions. Although comfortable interpersonal distance seems to be dependent on social factors such as the gender, age and activity of the confederates, it also seems to be modulated by the way we represent our peripersonal-action space. To test this hypothesis, the present study investigated the relation between the emotional responses registered through electrodermal activity (EDA) triggered by human-like point-light displays (PLDs) carrying different facial expressions (neutral, angry, happy) when located in the participants peripersonal or extrapersonal space, and the comfort distance with the same PLDs when approaching and crossing the participants fronto-parallel axis on the right or left side. The results show an increase of the phasic EDA for PLDs with angry facial expressions located in the peripersonal space (reachability judgment task), in comparison to the same PLDs located in the extrapersonal space, which was not observed for PLDs with neutral or happy facial expressions. The results also show an increase of the comfort distance for PLDs approaching the participants with an angry facial expression (interpersonal comfort distance judgment task), in comparison to PLDs with happy and neutral ones, which was related to the increase of the physiological response. Overall, the findings indicate that comfort social space can be predicted from the emotional reaction triggered by a confederate when located within the observer's peripersonal space. This suggests that peripersonal-action space and interpersonal-social space are similarly sensitive to the emotional valence of the confederate, which could reflect a common adaptive mechanism in specifying theses spaces to subtend interactions with both the physical and social environment, but also to ensure body protection from potential threats.

  16. Central and peripheral fatigue in knee and elbow extensor muscles after a long-distance cross-country ski race.

    PubMed

    Boccia, G; Dardanello, D; Zoppirolli, C; Bortolan, L; Cescon, C; Schneebeli, A; Vernillo, G; Schena, F; Rainoldi, A; Pellegrini, B

    2017-09-01

    Although elbow extensors (EE) have a great role in cross-country skiing (XC) propulsion, previous studies on neuromuscular fatigue in long-distance XC have investigated only knee extensor (KE) muscles. In order to investigate the origin and effects of fatigue induced by long-distance XC race, 16 well-trained XC skiers were tested before and after a 56-km classical technique race. Maximal voluntary isometric contraction (MVC) and rate of force development (RFD) were measured for both KE and EE. Furthermore, electrically evoked double twitch during MVC and at rest were measured. MVC decreased more in KE (-13%) than in EE (-6%, P = 0.016), whereas the peak RFD decreased only in EE (-26%, P = 0.02) but not in KE. The two muscles showed similar decrease in voluntary activation (KE -5.0%, EE -4.8%, P = 0.61) and of double twitch amplitude (KE -5%, EE -6%, P = 0.44). A long-distance XC race differently affected the neuromuscular function of lower and upper limbs muscles. Specifically, although the strength loss was greater for lower limbs, the capacity to produce force in short time was more affected in the upper limbs. Nevertheless, both KE and EE showed central and peripheral fatigue, suggesting that the origins of the strength impairments were multifactorial for the two muscles. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  17. Flagellin peptide flg22 gains access to long-distance trafficking in Arabidopsis via its receptor, FLS2

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jelenska, Joanna; Davern, Sandra M.; Standaert, Robert F.

    Diverse pathogen-derived molecules, such as bacterial flagellin and its conserved peptide flg22, are recognized in plants via plasma membrane receptors and induce both local and systemic immune responses. The fate of such ligands was unknown: whether and by what mechanism(s) they enter plant cells and whether they are transported to distal tissues. We used biologically active fluorophore and radiolabeled peptides to establish that flg22 moves to distal organs with the closest vascular connections. Remarkably, entry into the plant cell via endocytosis together with the FLS2 receptor is needed for delivery to vascular tissue and long-distance transport of flg22. This contrastsmore » with known routes of long distance transport of other non-cell-permeant molecules in plants, which require membrane-localized transporters for entry to vascular tissue. Thus, a plasma membrane receptor acts as a transporter to enable access of its ligand to distal trafficking routes.« less

  18. Flagellin peptide flg22 gains access to long-distance trafficking in Arabidopsis via its receptor, FLS2

    DOE PAGES

    Jelenska, Joanna; Davern, Sandra M.; Standaert, Robert F.; ...

    2017-03-01

    Diverse pathogen-derived molecules, such as bacterial flagellin and its conserved peptide flg22, are recognized in plants via plasma membrane receptors and induce both local and systemic immune responses. The fate of such ligands was unknown: whether and by what mechanism(s) they enter plant cells and whether they are transported to distal tissues. We used biologically active fluorophore and radiolabeled peptides to establish that flg22 moves to distal organs with the closest vascular connections. Remarkably, entry into the plant cell via endocytosis together with the FLS2 receptor is needed for delivery to vascular tissue and long-distance transport of flg22. This contrastsmore » with known routes of long distance transport of other non-cell-permeant molecules in plants, which require membrane-localized transporters for entry to vascular tissue. Thus, a plasma membrane receptor acts as a transporter to enable access of its ligand to distal trafficking routes.« less

  19. Design of a graphical and interactive interface for facilitating access to drug contraindications, cautions for use, interactions and adverse effects

    PubMed Central

    Lamy, Jean-Baptiste; Venot, Alain; Bar-Hen, Avner; Ouvrard, Patrick; Duclos, Catherine

    2008-01-01

    Background Drug iatrogeny is important but could be decreased if contraindications, cautions for use, drug interactions and adverse effects of drugs described in drug monographs were taken into account. However, the physician's time is limited during consultations, and this information is often not consulted. We describe here the design of "Mister VCM", a graphical interface based on the VCM graphical language, facilitating access to drug monographs. We also provide an assessment of the usability of this interface. Methods The "Mister VCM" interface was designed by dividing the screen into two parts: a graphical interactive one including VCM icons and synthetizing drug properties, a textual one presenting on demand drug monograph excerpts. The interface was evaluated over 11 volunteer general practitioners, trained in the use of "Mister VCM". They were asked to answer clinical questions related to fictitious randomly generated drug monographs, using a textual interface or "Mister VCM". When answering the questions, correctness of the responses and response time were recorded. Results "Mister VCM" is an interactive interface that displays VCM icons organized around an anatomical diagram of the human body with additional mental, etiological and physiological areas. Textual excerpts of the drug monograph can be displayed by clicking on the VCM icons. The interface can explicitly represent information implicit in the drug monograph, such as the absence of a given contraindication. Physicians made fewer errors with "Mister VCM" than with text (factor of 1.7; p = 0.034) and responded to questions 2.2 times faster (p < 0.001). The time gain with "Mister VCM" was greater for long monographs and questions with implicit replies. Conclusion "Mister VCM" seems to be a promising interface for accessing drug monographs. Similar interfaces could be developed for other medical domains, such as electronic patient records. PMID:18518945

  20. Distance Teacher Education in Pakistan

    ERIC Educational Resources Information Center

    Jumani, Nabi Bux; Zai, Zafar Iqbal Yousuf

    2009-01-01

    Distance education means instruction in which the instructor and student are separated by distance and interact through the assistance of communication technology. Distance education changes the learning relationship from the common, centralized school model to a more decentralized, flexible model. It also reverses social dynamics by bringing…

  1. New evidence for long-distance fluid migration within the Earth's crust

    NASA Astrophysics Data System (ADS)

    Person, M.; Baumgartner, L.

    1995-07-01

    During the past decade, geologists have come to appreciate the interconnectedness of hydrologic, tectonic, thermal, and geochemical processes operating within the Earth's continental crust [Oliver, 1992]. This has led to a new geologically-based conceptual model of hydrology which is crustal-scale and is centered in plate tectonics theory (Fig. 1). From a geological perspective, the tectonic and thermal processes which drive plate motion are also responsible, either directly or indirectly, for inducing fluid motion across and through the continents. Supporting evidence for this emerging paradigm is based on observations of pervasive rock-water interactions associated with geologic processes as diverse as the chemical alteration of crustal rocks [Shelton et al, 1992; Elliott and Aronson, 1993; McManus and Hanor, 1993; Ague, 1991, 1994], devolatilization of minerals during burial and consequent metamorphism [Cox and Etheridge, 1989], the formation of energy and mineral deposits [Garven et al, 1993; and Cathles et al, 1993], remagnitization of ancient sedimentary rocks [McCabe and Elmore, 1989], the tectonic deformation of sedimentary basins [Oliver 1992, Ge and Garven, 1992], and the regulation of global climate [Caldeira et al, 1993, Kerrick and Caldeira, 1993, 1994]. This paper summarizes the many recent lines of theoretical, laboratory, and field evidence from diverse disciplines within the Earth Sciences supporting this emerging view of crustal-scale hydrology. Evidence for two types of long-distance fluid migration are highlighted: vertical pore water movement through crystalline rocks to depths greater than six km and lateral groundwater movement through sedimentary basins over hundereds of km. Also emphasized are the many driving mechanisms on fluid motion which are not typically considered in water quality and water supply investigations. Some geologic terms used in this paper, which may be unfamiliar to the reader, are defined in geologic dictionaries

  2. Distance to high-voltage power lines and risk of childhood leukemia--an analysis of confounding by and interaction with other potential risk factors.

    PubMed

    Pedersen, Camilla; Bräuner, Elvira V; Rod, Naja H; Albieri, Vanna; Andersen, Claus E; Ulbak, Kaare; Hertel, Ole; Johansen, Christoffer; Schüz, Joachim; Raaschou-Nielsen, Ole

    2014-01-01

    We investigated whether there is an interaction between distance from residence at birth to nearest power line and domestic radon and traffic-related air pollution, respectively, in relation to childhood leukemia risk. Further, we investigated whether adjusting for potential confounders alters the association between distance to nearest power line and childhood leukemia. We included 1024 cases aged <15, diagnosed with leukemia during 1968-1991, from the Danish Cancer Registry and 2048 controls randomly selected from the Danish childhood population and individually matched by gender and year of birth. We used geographical information systems to determine the distance between residence at birth and the nearest 132-400 kV overhead power line. Concentrations of domestic radon and traffic-related air pollution (NOx at the front door) were estimated using validated models. We found a statistically significant interaction between distance to nearest power line and domestic radon regarding risk of childhood leukemia (p = 0.01) when using the median radon level as cut-off point but not when using the 75th percentile (p = 0.90). We found no evidence of an interaction between distance to nearest power line and traffic-related air pollution (p = 0.73). We found almost no change in the estimated association between distance to power line and risk of childhood leukemia when adjusting for socioeconomic status of the municipality, urbanization, maternal age, birth order, domestic radon and traffic-related air pollution. The statistically significant interaction between distance to nearest power line and domestic radon was based on few exposed cases and controls and sensitive to the choice of exposure categorization and might, therefore, be due to chance.

  3. Facilitation among plants in alpine environments in the face of climate change

    PubMed Central

    Anthelme, Fabien; Cavieres, Lohengrin A.; Dangles, Olivier

    2014-01-01

    While there is a large consensus that plant–plant interactions are a crucial component of the response of plant communities to the effects of climate change, available data remain scarce, particularly in alpine systems. This represents an important obstacle to making consistent predictions about the future of plant communities. Here, we review current knowledge on the effects of climate change on facilitation among alpine plant communities and propose directions for future research. In established alpine communities, while warming seemingly generates a net facilitation release, earlier snowmelt may increase facilitation. Some nurse plants are able to buffer microenvironmental changes in the long term and may ensure the persistence of other alpine plants through local migration events. For communities migrating to higher elevations, facilitation should play an important role in their reorganization because of the harsher environmental conditions. In particular, the absence of efficient nurse plants might slow down upward migration, possibly generating chains of extinction. Facilitation–climate change relationships are expected to shift along latitudinal gradients because (1) the magnitude of warming is predicted to vary along these gradients, and (2) alpine environments are significantly different at low vs. high latitudes. Data on these expected patterns are preliminary and thus need to be tested with further studies on facilitation among plants in alpine environments that have thus far not been considered. From a methodological standpoint, future studies will benefit from the spatial representation of the microclimatic environment of plants to predict their response to climate change. Moreover, the acquisition of long-term data on the dynamics of plant–plant interactions, either through permanent plots or chronosequences of glacial recession, may represent powerful approaches to clarify the relationship between plant interactions and climate change. PMID

  4. Evidence against the facilitation of the vergence command during saccade-vergence interactions.

    PubMed

    Hendel, Tal; Gur, Moshe

    2012-11-01

    Combined saccade-vergence movements result when gaze shifts are made to targets that differ both in direction and in depth from the momentary fixation point. Currently, there are two rivaling schemes to explain these eye movements. According to the first, such eye movements are due to a combination of a conjugate saccadic command and a symmetric vergence command; the two commands are not taken to be independent but instead are suggested to interact in a nonlinear manner, which leads to an intra-saccadic facilitation of the vergence command. According to the second scheme, the saccade generator is disconjugate, thus encoding vergence information in the saccadic commands themselves, and the remaining vergence requirement is provided by an asymmetric mechanism. Here, we test the scheme that suggests an intra-saccadic facilitation of the vergence command. We analyze this scheme and show that it has two fundamental properties. The first is that the vergence command is always symmetric, even during the intra-saccadic facilitation. The second is that the facilitated (and symmetric) vergence command sums linearly with the conjugate saccadic command at the final common pathway. Taking these properties together, this scheme predicts that the total magnitude of the saccadic component of combined saccade-vergence movements can be decomposed into a conjugate part and a symmetric part. When we tested this prediction in combined saccade-vergence movements of humans, we found that it was not confirmed. Thus, our results are incompatible with the facilitation of the vergence command hypothesis. Although these results do not directly verify the rivaling hypothesis, which suggests a disconjugate saccade generator, they do provide it with indirect support.

  5. A model of urban scaling laws based on distance dependent interactions

    NASA Astrophysics Data System (ADS)

    Ribeiro, Fabiano L.; Meirelles, Joao; Ferreira, Fernando F.; Neto, Camilo Rodrigues

    2017-03-01

    Socio-economic related properties of a city grow faster than a linear relationship with the population, in a log-log plot, the so-called superlinear scaling. Conversely, the larger a city, the more efficient it is in the use of its infrastructure, leading to a sublinear scaling on these variables. In this work, we addressed a simple explanation for those scaling laws in cities based on the interaction range between the citizens and on the fractal properties of the cities. To this purpose, we introduced a measure of social potential which captured the influence of social interaction on the economic performance and the benefits of amenities in the case of infrastructure offered by the city. We assumed that the population density depends on the fractal dimension and on the distance-dependent interactions between individuals. The model suggests that when the city interacts as a whole, and not just as a set of isolated parts, there is improvement of the socio-economic indicators. Moreover, the bigger the interaction range between citizens and amenities, the bigger the improvement of the socio-economic indicators and the lower the infrastructure costs of the city. We addressed how public policies could take advantage of these properties to improve cities development, minimizing negative effects. Furthermore, the model predicts that the sum of the scaling exponents of social-economic and infrastructure variables are 2, as observed in the literature. Simulations with an agent-based model are confronted with the theoretical approach and they are compatible with the empirical evidences.

  6. A model of urban scaling laws based on distance dependent interactions

    PubMed Central

    Ribeiro, Fabiano L.; Meirelles, Joao; Ferreira, Fernando F.

    2017-01-01

    Socio-economic related properties of a city grow faster than a linear relationship with the population, in a log–log plot, the so-called superlinear scaling. Conversely, the larger a city, the more efficient it is in the use of its infrastructure, leading to a sublinear scaling on these variables. In this work, we addressed a simple explanation for those scaling laws in cities based on the interaction range between the citizens and on the fractal properties of the cities. To this purpose, we introduced a measure of social potential which captured the influence of social interaction on the economic performance and the benefits of amenities in the case of infrastructure offered by the city. We assumed that the population density depends on the fractal dimension and on the distance-dependent interactions between individuals. The model suggests that when the city interacts as a whole, and not just as a set of isolated parts, there is improvement of the socio-economic indicators. Moreover, the bigger the interaction range between citizens and amenities, the bigger the improvement of the socio-economic indicators and the lower the infrastructure costs of the city. We addressed how public policies could take advantage of these properties to improve cities development, minimizing negative effects. Furthermore, the model predicts that the sum of the scaling exponents of social-economic and infrastructure variables are 2, as observed in the literature. Simulations with an agent-based model are confronted with the theoretical approach and they are compatible with the empirical evidences. PMID:28405381

  7. A model of urban scaling laws based on distance dependent interactions.

    PubMed

    Ribeiro, Fabiano L; Meirelles, Joao; Ferreira, Fernando F; Neto, Camilo Rodrigues

    2017-03-01

    Socio-economic related properties of a city grow faster than a linear relationship with the population, in a log-log plot, the so-called superlinear scaling . Conversely, the larger a city, the more efficient it is in the use of its infrastructure, leading to a sublinear scaling on these variables. In this work, we addressed a simple explanation for those scaling laws in cities based on the interaction range between the citizens and on the fractal properties of the cities. To this purpose, we introduced a measure of social potential which captured the influence of social interaction on the economic performance and the benefits of amenities in the case of infrastructure offered by the city. We assumed that the population density depends on the fractal dimension and on the distance-dependent interactions between individuals. The model suggests that when the city interacts as a whole, and not just as a set of isolated parts, there is improvement of the socio-economic indicators. Moreover, the bigger the interaction range between citizens and amenities, the bigger the improvement of the socio-economic indicators and the lower the infrastructure costs of the city. We addressed how public policies could take advantage of these properties to improve cities development, minimizing negative effects. Furthermore, the model predicts that the sum of the scaling exponents of social-economic and infrastructure variables are 2, as observed in the literature. Simulations with an agent-based model are confronted with the theoretical approach and they are compatible with the empirical evidences.

  8. Inclusive Approach to the Psycho-Pedagogical Assistance of Distance Learning

    ERIC Educational Resources Information Center

    Akhmetova, Daniya Z.

    2014-01-01

    Author focuses on three groups of problems: quality of distance learning and e-learning; necessity to develop the facilitation skills for teachers who work using distance learning technologies; realization of inclusive approach for the organization of distance learning in inclusive groups where people with disabilities study with people without…

  9. Vascular Sap Proteomics: Providing Insight into Long-Distance Signaling during Stress

    PubMed Central

    Carella, Philip; Wilson, Daniel C.; Kempthorne, Christine J.; Cameron, Robin K.

    2016-01-01

    The plant vascular system, composed of the xylem and phloem, is important for the transport of water, mineral nutrients, and photosynthate throughout the plant body. The vasculature is also the primary means by which developmental and stress signals move from one organ to another. Due to practical and technological limitations, proteomics analysis of xylem and phloem sap has been understudied in comparison to accessible sample types such as leaves and roots. However, recent advances in sample collection techniques and mass spectrometry technology are making it possible to comprehensively analyze vascular sap proteomes. In this mini-review, we discuss the emerging field of vascular sap proteomics, with a focus on recent comparative studies to identify vascular proteins that may play roles in long-distance signaling and other processes during stress responses in plants. PMID:27242852

  10. Quantum Spin Dynamics with Pairwise-Tunable, Long-Range Interactions

    DTIC Science & Technology

    2016-08-05

    rection of the arrows. Dashed (dotted) lines mark the NNN hopping terms (coefficients ±t2). NNNN long -range hopping along curved lines are included to...Quantum spin dynamics with pairwise-tunable, long -range interactions C.-L. Hunga,b,1,2, Alejandro González-Tudelac,1,2, J. Ignacio Ciracc, and H. J...atoms) that interact by way of a variety of processes, such as atomic collisions. Such pro- cesses typically lead to short -range, nearest-neighbor

  11. Optimal energy-utilization ratio for long-distance cruising of a model fish

    NASA Astrophysics Data System (ADS)

    Liu, Geng; Yu, Yong-Liang; Tong, Bing-Gang

    2012-07-01

    The efficiency of total energy utilization and its optimization for long-distance migration of fish have attracted much attention in the past. This paper presents theoretical and computational research, clarifying the above well-known classic questions. Here, we specify the energy-utilization ratio (fη) as a scale of cruising efficiency, which consists of the swimming speed over the sum of the standard metabolic rate and the energy consumption rate of muscle activities per unit mass. Theoretical formulation of the function fη is made and it is shown that based on a basic dimensional analysis, the main dimensionless parameters for our simplified model are the Reynolds number (Re) and the dimensionless quantity of the standard metabolic rate per unit mass (Rpm). The swimming speed and the hydrodynamic power output in various conditions can be computed by solving the coupled Navier-Stokes equations and the fish locomotion dynamic equations. Again, the energy consumption rate of muscle activities can be estimated by the quotient of dividing the hydrodynamic power by the muscle efficiency studied by previous researchers. The present results show the following: (1) When the value of fη attains a maximum, the dimensionless parameter Rpm keeps almost constant for the same fish species in different sizes. (2) In the above cases, the tail beat period is an exponential function of the fish body length when cruising is optimal, e.g., the optimal tail beat period of Sockeye salmon is approximately proportional to the body length to the power of 0.78. Again, the larger fish's ability of long-distance cruising is more excellent than that of smaller fish. (3) The optimal swimming speed we obtained is consistent with previous researchers’ estimations.

  12. Super long viewing distance light homogeneous emitting three-dimensional display

    NASA Astrophysics Data System (ADS)

    Liao, Hongen

    2015-04-01

    Three-dimensional (3D) display technology has continuously been attracting public attention with the progress in today's 3D television and mature display technologies. The primary characteristics of conventional glasses-free autostereoscopic displays, such as spatial resolution, image depths, and viewing angle, are often limited due to the use of optical lenses or optical gratings. We present a 3D display using MEMS-scanning-mechanism-based light homogeneous emitting (LHE) approach and demonstrate that the display can directly generate an autostereoscopic 3D image without the need for optical lenses or gratings. The generated 3D image has the advantages of non-aberration and a high-definition spatial resolution, making it the first to exhibit animated 3D images with image depth of six meters. Our LHE 3D display approach can be used to generate a natural flat-panel 3D display with super long viewing distance and alternative real-time image update.

  13. Long distance measurement with a femtosecond laser based frequency comb

    NASA Astrophysics Data System (ADS)

    Bhattacharya, N.; Cui, M.; Zeitouny, M. G.; Urbach, H. P.; van den Berg, S. A.

    2017-11-01

    Recent advances in the field of ultra-short pulse lasers have led to the development of reliable sources of carrier envelope phase stabilized femtosecond pulses. The pulse train generated by such a source has a frequency spectrum that consists of discrete, regularly spaced lines known as a frequency comb. In this case both the frequency repetition and the carrier-envelope-offset frequency are referenced to a frequency standard, like an atomic clock. As a result the accuracy of the frequency standard is transferred to the optical domain, with the frequency comb as transfer oscillator. These unique properties allow the frequency comb to be applied as a versatile tool, not only for time and frequency metrology, but also in fundamental physics, high-precision spectroscopy, and laser noise characterization. The pulse-to-pulse phase relationship of the light emitted by the frequency comb has opened up new directions for long range highly accurate distance measurement.

  14. Very rapid long-distance sea crossing by a migratory bird

    PubMed Central

    Alves, José A.; Dias, Maria P.; Méndez, Verónica; Katrínardóttir, Borgný; Gunnarsson, Tómas G.

    2016-01-01

    Landbirds undertaking within-continent migrations have the possibility to stop en route, but most long-distance migrants must also undertake large non-stop sea crossings, the length of which can vary greatly. For shorebirds migrating from Iceland to West Africa, the shortest route would involve one of the longest continuous sea crossings while alternative, mostly overland, routes are available. Using geolocators to track the migration of Icelandic whimbrels (Numenius phaeopus), we show that they can complete a round-trip of 11,000 km making two non-stop sea crossings and flying at speeds of up to 24 m s−1; the fastest recorded for shorebirds flying over the ocean. Although wind support could reduce flight energetic costs, whimbrels faced headwinds up to twice their ground speed, indicating that unfavourable and potentially fatal weather conditions are not uncommon. Such apparently high risk migrations might be more common than previously thought, with potential fitness gains outweighing the costs. PMID:27901077

  15. A Selfish Constraint Satisfaction Genetic Algorithms for Planning a Long-Distance Transportation Network

    NASA Astrophysics Data System (ADS)

    Onoyama, Takashi; Maekawa, Takuya; Kubota, Sen; Tsuruta, Setuso; Komoda, Norihisa

    To build a cooperative logistics network covering multiple enterprises, a planning method that can build a long-distance transportation network is required. Many strict constraints are imposed on this type of problem. To solve these strict-constraint problems, a selfish constraint satisfaction genetic algorithm (GA) is proposed. In this GA, each gene of an individual satisfies only its constraint selfishly, disregarding the constraints of other genes in the same individuals. Moreover, a constraint pre-checking method is also applied to improve the GA convergence speed. The experimental result shows the proposed method can obtain an accurate solution in a practical response time.

  16. US long distance fiber optic networks: Technology, evolution and advanced concepts. Volume 1: Executive summary

    NASA Technical Reports Server (NTRS)

    1986-01-01

    Over the past two decades, fiber optics has emerged as a highly practical and cost-efficient communications technology. Its competitiveness vis-a-vis other transmission media, especially satellite, has become a critical question. This report studies the likely evolution and application of fiber optic networks in the United States to the end of the century. The outlook for the technology of fiber systems is assessed and forecast, scenarios of the evolution of fiber optic network development are constructed, and costs to provide service are determined and examined parametrically as a function of network size and traffic carried. Volume 1 consists of the Executive Summary. Volume 2 focuses on fiber optic technology and long distance fiber optic networks. Volume 3 develops a traffic and financial model of a nationwide long distance transmission network. Among the study's most important conclusions are: revenue requirements per circuit for LATA-to-LATA fiber optic links are less than one cent per call minute; multiplex equipment, which is likely to be required in any competing system, is the largest contributor to circuit costs; the potential capacity of fiber optic cable is very large and as yet undefined; and fiber optic transmission combined with other network optimization schemes can lead to even lower costs than those identified in this study.

  17. Long distance measurement-device-independent quantum key distribution with entangled photon sources

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Xu, Feihu; Qi, Bing; Liao, Zhongfa

    2013-08-05

    We present a feasible method that can make quantum key distribution (QKD), both ultra-long-distance and immune, to all attacks in the detection system. This method is called measurement-device-independent QKD (MDI-QKD) with entangled photon sources in the middle. By proposing a model and simulating a QKD experiment, we find that MDI-QKD with one entangled photon source can tolerate 77 dB loss (367 km standard fiber) in the asymptotic limit and 60 dB loss (286 km standard fiber) in the finite-key case with state-of-the-art detectors. Our general model can also be applied to other non-QKD experiments involving entanglement and Bell state measurements.

  18. Long-Distance Free Fall

    NASA Astrophysics Data System (ADS)

    Gallant, Joseph

    1999-04-01

    One of the goals of physics education is to instill a sense of wonder in our students. We hope our natural curiosity will rub off on them and that they will apply the critical thinking skills we teach them to other aspects of their lives outside the classroom. As an example of this, consider the situation described in Milton's epic poem ``Paradise Lost''. Milton wrote that when the devil was cast out of heaven, he fell for nine days before landing in hell. In Milton's universe, hell is a separate place from Earth, but many people place hell at the center of the Earth. Based on these ideas, we can apply Newton's laws of motion to calculate the distance from heaven to Earth. This exercise is an example of the kind of intellectual exercise a physicist (or a physics student) might carry out when confronted with such information. We apply the basic principles of physics to a situation described in work of literature while making no attempt to validate or refute any philosophy, theology or ideology.

  19. Swimming performances in long distance open-water events with and without wetsuit

    PubMed Central

    2014-01-01

    Background Existing literature showed improved swimming performances for swimmers wearing wetsuits competing under standardized conditions in races held in pools on short to middle distances. Data about the influence of wetsuits on swimming performances in long and ultra-long open-water swimming races are missing. It is unknown whether the benefit of wearing wetsuits is comparable in men and women. The aim of this study was to investigate the influence of wearing a wetsuit on open-water swimming performances at the 26.4 km ‘Marathon Swim in Lake Zurich’ in Lake Zurich, Switzerland, and the 3.8 km Lake Ontario Swim Team-Race (LOST-Race) in Lake Ontario, Canada. Methods Race times of the fastest female and male swimmers competing with and without wetsuit were compared using multi-level regression analyses and analysis of variance. Results In the ‘Marathon Swim’ in Lake Zurich, wearing a wetsuit had no effect on race time regarding the gender where athletes wearing a wetsuit were not faster than athletes without wetsuit. However, the ten fastest men wearing a wetsuit (410.6 ± 26.7 min) were faster (32.7%, p < 0.01) than the ten fastest women without wetsuit (544.9 ± 81.3 min). In the ‘LOST-Race’, the top ten men wearing a wetsuit (51.7 ± 2.5 min) were faster (13.2%, p < 0.01) than the top ten women wearing a wetsuit (58.5 ± 3.2 min). Additionally, the top ten men without wetsuit (52.1 ± 2.4 min) were faster (19.6%, p < 0.01) than the top ten women without wetsuit (62.3 ± 2.5 min). The top ten women wearing a wetsuit (58.5 ± 3.2 min) were faster (6.5%, p < 0.01) than top ten women without a wetsuit (62.3 ± 25 min). Conclusions These results suggest that wearing a wetsuit had a positive influence on swimming speed for both women and men but the benefit of the use of wetsuits seemed to depend on additional factors (i.e. race distance). Women seemed to benefit more from wearing wetsuits than men in longer

  20. Consequences of long-distance swimming and travel over deep-water pack ice for a female polar bear during a year of extreme sea ice retreat

    USGS Publications Warehouse

    Durner, George M.; Whiteman, J.P.; Harlow, H.J.; Amstrup, Steven C.; Regehr, E.V.; Ben-David, M.

    2011-01-01

    Polar bears (Ursus maritimus) prefer to live on Arctic sea ice but may swim between ice floes or between sea ice and land. Although anecdotal observations suggest that polar bears are capable of swimming long distances, no data have been available to describe in detail long distance swimming events or the physiological and reproductive consequences of such behavior. Between an initial capture in late August and a recapture in late October 2008, a radio-collared adult female polar bear in the Beaufort Sea made a continuous swim of 687 km over 9 days and then intermittently swam and walked on the sea ice surface an additional 1,800 km. Measures of movement rate, hourly activity, and subcutaneous and external temperature revealed distinct profiles of swimming and walking. Between captures, this polar bear lost 22% of her body mass and her yearling cub. The extraordinary long distance swimming ability of polar bears, which we confirm here, may help them cope with reduced Arctic sea ice. Our observation, however, indicates that long distance swimming in Arctic waters, and travel over deep water pack ice, may result in high energetic costs and compromise reproductive fitness.

  1. Teacher-Child Interactions in Voluntary Pre-Kindergarten Programs in Child Care Settings: A Critical Analysis of Barriers and Facilitators

    ERIC Educational Resources Information Center

    Kim, Seunghee

    2008-01-01

    We investigated barriers to and facilitators of effective teacher-child interactions in voluntary pre-kindergarten programs in child care settings. An effective teacher-child interaction enables both teachers and children to actively engage in solving the problems they confront in their daily lives. The effective teacher-child interaction relies…

  2. A long distance voice transmission system based on the white light LED

    NASA Astrophysics Data System (ADS)

    Tian, Chunyu; Wei, Chang; Wang, Yulian; Wang, Dachi; Yu, Benli; Xu, Feng

    2017-10-01

    A long distance voice transmission system based on a visible light communication technology (VLCT) is proposed in the paper. Our proposed system includes transmitter, receiver and the voice signal processing of single chip microcomputer. In the compact-sized LED transmitter, we use on-off-keying and not-return-to-zero (OOK-NRZ) to easily realize high speed modulation, and then systematic complexity is reduced. A voice transmission system, which possesses the properties of the low-noise and wide modulation band, is achieved by the design of high efficiency receiving optical path and using filters to reduce noise from the surrounding light. To improve the speed of the signal processing, we use single chip microcomputer to code and decode voice signal. Furthermore, serial peripheral interface (SPI) is adopted to accurately transmit voice signal data. The test results of our proposed system show that the transmission distance of this system is more than100 meters with the maximum data rate of 1.5 Mbit/s and a SNR of 30dB. This system has many advantages, such as simple construction, low cost and strong practicality. Therefore, it has extensive application prospect in the fields of the emergency communication and indoor wireless communication, etc.

  3. Facilitation influences patterns of perennial species abundance and richness in a subtropical dune system.

    PubMed

    Dalotto, Cecilia E S; Sühs, Rafael B; Dechoum, Michele S; Pugnaire, Francisco I; Peroni, Nivaldo; Castellani, Tânia T

    2018-04-01

    Positive interactions in plant communities are under-reported in subtropical systems most likely because they are not identified as stressful environments. However, environmental factors or disturbance can limit plant growth in any system and lead to stressful conditions. For instance, salinity and low nutrient and water availability generate a gradient of stressful conditions in coastal systems depending on distance to shore. In a tropical coastal system in SE Brazil, we aimed to assess whether Guapira opposita , a shrub common in restinga environments, acted as nurse involved in ecological succession and which factors influenced its facilitation process. We sampled perennial species above 10 cm in height under the canopy of 35 G. opposita individuals and in neighbouring open areas. Shrub height, canopy area and distance to freshwater bodies were measured in the field, and distance to the ocean was obtained from aerial images. In addition, we measured the distance to the closest forest patch as a potential source of seeds. Plant abundance and species richness were higher under the canopy of G. opposita than in open areas. Facilitation by G. opposita was mainly determined by shrub height, which had a positive relationship with woody and bromeliads abundance and species richness while there was no relationship with the other factors. Overall, our data evidence that tropical environments may be highly stressful for plants and that nurse species play a key role in the regeneration of restinga environments, where their presence is critical to maintain ecosystem diversity and function.

  4. Source-receptor probability of atmospheric long-distance dispersal of viruses to Israel from the eastern Mediterranean area.

    PubMed

    Klausner, Z; Klement, E; Fattal, E

    2018-02-01

    Viruses that affect the health of humans and farm animals can spread over long distances via atmospheric mechanisms. The phenomenon of atmospheric long-distance dispersal (LDD) is associated with severe consequences because it may introduce pathogens into new areas. The introduction of new pathogens to Israel was attributed to LDD events numerous times. This provided the motivation for this study which is aimed to identify all the locations in the eastern Mediterranean that may serve as sources for pathogen incursion into Israel via LDD. This aim was achieved by calculating source-receptor relationship probability maps. These maps describe the probability that an infected vector or viral aerosol, once airborne, will have an atmospheric route that can transport it to a distant location. The resultant probability maps demonstrate a seasonal tendency in the probability of specific areas to serve as sources for pathogen LDD into Israel. Specifically, Cyprus' season is the summer; southern Turkey and the Greek islands of Crete, Karpathos and Rhodes are associated with spring and summer; lower Egypt and Jordan may serve as sources all year round, except the summer months. The method used in this study can easily be implemented to any other geographic region. The importance of this study is the ability to provide a climatologically valid and accurate risk assessment tool to support long-term decisions regarding preparatory actions for future outbreaks long before a specific outbreak occurs. © 2017 Blackwell Verlag GmbH.

  5. Dynamic Interaction of Long Suspension Bridges with Running Trains

    NASA Astrophysics Data System (ADS)

    XIA, H.; XU, Y. L.; CHAN, T. H. T.

    2000-10-01

    This paper presents an investigation of dynamic interaction of long suspension bridges with running trains. A three-dimensional finite element model is used to represent a long suspension bridge. Each 4-axle vehicle in a train is modelled by a 27-degrees-of-freedom dynamic system. The dynamic interaction between the bridge and train is realized through the contact forces between the wheels and track. By applying a mode superposition technique to the bridge only and taking the measured track irregularities as known quantities, the number of degrees of freedom (d.o.f.) the bridge-train system is significantly reduced and the coupled equations of motion are efficiently solved. The proposed formulation and the associated computer program are then applied to a real long suspension bridge carrying a railway within the bridge deck. The dynamic response of the bridge-train system and the derail and offload factors related to the running safety of the train are computed. The results show that the formulation presented in this paper can well predict dynamic behaviors of both bridge and train with reasonable computation efforts. Dynamic interaction between the long suspension bridge and train is not significant.

  6. Long-distance dispersal of the coconut palm by migration within the coral atoll ecosystem

    PubMed Central

    Harries, Hugh C.; Clement, Charles R.

    2014-01-01

    Background The location of the original home of the coconut palm, Cocos nucifera, and the extent of its natural dispersal are not known. Proponents of a South American origin must explain why it is not indigenous there and why it shows greatest diversity in southern Asia. Conversely, proponents of an Asian origin must explain why there are no Asian Cocoseae and why the closest botanical relative to Cocos is in South America. Both hypotheses share the common problems of how, when, where and in what directions long-distance dispersal occurred. Hypothesis These difficulties are resolved by accepting that C. nucifera originated and dispersed by populating emerging islands of the coral atoll ecosystem, where establishment conditions impose high selection pressures for survival. When lifted by wave action onto virtually sterile, soilless coralline rocks just above sea level and exposed to the full impact of the sun, seednuts must germinate, root and establish vigorous populations. The cavity within the nut augments the buoyancy provided by the thick husk, which in turn protects the embryo and, by delaying germination, simultaneously extends viability while floating and provides a moisture-retentive rooting medium for the young seedling. These adaptations allow coconuts to disperse widely through the coral atoll ecosystem. Conclusions The monthly production of fruit and the long floating duration ensure that viable seednuts are always available in the lagoon to replace those destroyed by hurricanes and tsunamis, or to populate newly emerged coral atolls elsewhere. Long-distance dispersal is secondary, because it was the spontaneous, independent migration of coral polyps on a prolonged geological time scale that generated new coral atolls in new areas where the coconuts would be amongst the earliest inhabitants. The coconut palm became an intermittent, itinerant, pioneer endemic there, and also on suitable beaches on volcanic or large islands and continental coastlines

  7. Long-distance dispersal of the coconut palm by migration within the coral atoll ecosystem.

    PubMed

    Harries, Hugh C; Clement, Charles R

    2014-03-01

    The location of the original home of the coconut palm, Cocos nucifera, and the extent of its natural dispersal are not known. Proponents of a South American origin must explain why it is not indigenous there and why it shows greatest diversity in southern Asia. Conversely, proponents of an Asian origin must explain why there are no Asian Cocoseae and why the closest botanical relative to Cocos is in South America. Both hypotheses share the common problems of how, when, where and in what directions long-distance dispersal occurred. These difficulties are resolved by accepting that C. nucifera originated and dispersed by populating emerging islands of the coral atoll ecosystem, where establishment conditions impose high selection pressures for survival. When lifted by wave action onto virtually sterile, soilless coralline rocks just above sea level and exposed to the full impact of the sun, seednuts must germinate, root and establish vigorous populations. The cavity within the nut augments the buoyancy provided by the thick husk, which in turn protects the embryo and, by delaying germination, simultaneously extends viability while floating and provides a moisture-retentive rooting medium for the young seedling. These adaptations allow coconuts to disperse widely through the coral atoll ecosystem. The monthly production of fruit and the long floating duration ensure that viable seednuts are always available in the lagoon to replace those destroyed by hurricanes and tsunamis, or to populate newly emerged coral atolls elsewhere. Long-distance dispersal is secondary, because it was the spontaneous, independent migration of coral polyps on a prolonged geological time scale that generated new coral atolls in new areas where the coconuts would be amongst the earliest inhabitants. The coconut palm became an intermittent, itinerant, pioneer endemic there, and also on suitable beaches on volcanic or large islands and continental coastlines.

  8. Working memory differences in long-distance dependency resolution

    PubMed Central

    Nicenboim, Bruno; Vasishth, Shravan; Gattei, Carolina; Sigman, Mariano; Kliegl, Reinhold

    2015-01-01

    There is a wealth of evidence showing that increasing the distance between an argument and its head leads to more processing effort, namely, locality effects; these are usually associated with constraints in working memory (DLT: Gibson, 2000; activation-based model: Lewis and Vasishth, 2005). In SOV languages, however, the opposite effect has been found: antilocality (see discussion in Levy et al., 2013). Antilocality effects can be explained by the expectation-based approach as proposed by Levy (2008) or by the activation-based model of sentence processing as proposed by Lewis and Vasishth (2005). We report an eye-tracking and a self-paced reading study with sentences in Spanish together with measures of individual differences to examine the distinction between expectation- and memory-based accounts, and within memory-based accounts the further distinction between DLT and the activation-based model. The experiments show that (i) antilocality effects as predicted by the expectation account appear only for high-capacity readers; (ii) increasing dependency length by interposing material that modifies the head of the dependency (the verb) produces stronger facilitation than increasing dependency length with material that does not modify the head; this is in agreement with the activation-based model but not with the expectation account; and (iii) a possible outcome of memory load on low-capacity readers is the increase in regressive saccades (locality effects as predicted by memory-based accounts) or, surprisingly, a speedup in the self-paced reading task; the latter consistent with good-enough parsing (Ferreira et al., 2002). In sum, the study suggests that individual differences in working memory capacity play a role in dependency resolution, and that some of the aspects of dependency resolution can be best explained with the activation-based model together with a prediction component. PMID:25852623

  9. Working memory differences in long-distance dependency resolution.

    PubMed

    Nicenboim, Bruno; Vasishth, Shravan; Gattei, Carolina; Sigman, Mariano; Kliegl, Reinhold

    2015-01-01

    There is a wealth of evidence showing that increasing the distance between an argument and its head leads to more processing effort, namely, locality effects; these are usually associated with constraints in working memory (DLT: Gibson, 2000; activation-based model: Lewis and Vasishth, 2005). In SOV languages, however, the opposite effect has been found: antilocality (see discussion in Levy et al., 2013). Antilocality effects can be explained by the expectation-based approach as proposed by Levy (2008) or by the activation-based model of sentence processing as proposed by Lewis and Vasishth (2005). We report an eye-tracking and a self-paced reading study with sentences in Spanish together with measures of individual differences to examine the distinction between expectation- and memory-based accounts, and within memory-based accounts the further distinction between DLT and the activation-based model. The experiments show that (i) antilocality effects as predicted by the expectation account appear only for high-capacity readers; (ii) increasing dependency length by interposing material that modifies the head of the dependency (the verb) produces stronger facilitation than increasing dependency length with material that does not modify the head; this is in agreement with the activation-based model but not with the expectation account; and (iii) a possible outcome of memory load on low-capacity readers is the increase in regressive saccades (locality effects as predicted by memory-based accounts) or, surprisingly, a speedup in the self-paced reading task; the latter consistent with good-enough parsing (Ferreira et al., 2002). In sum, the study suggests that individual differences in working memory capacity play a role in dependency resolution, and that some of the aspects of dependency resolution can be best explained with the activation-based model together with a prediction component.

  10. Live-cell imaging of Marburg virus-infected cells uncovers actin-dependent transport of nucleocapsids over long distances

    PubMed Central

    Schudt, Gordian; Kolesnikova, Larissa; Dolnik, Olga; Sodeik, Beate; Becker, Stephan

    2013-01-01

    Transport of large viral nucleocapsids from replication centers to assembly sites requires contributions from the host cytoskeleton via cellular adaptor and motor proteins. For the Marburg and Ebola viruses, related viruses that cause severe hemorrhagic fevers, the mechanism of nucleocapsid transport remains poorly understood. Here we developed and used live-cell imaging of fluorescently labeled viral and host proteins to characterize the dynamics and molecular requirements of nucleocapsid transport in Marburg virus-infected cells under biosafety level 4 conditions. The study showed a complex actin-based transport of nucleocapsids over long distances from the viral replication centers to the budding sites. Only after the nucleocapsids had associated with the matrix viral protein VP40 at the plasma membrane were they recruited into filopodia and cotransported with host motor myosin 10 toward the budding sites at the tip or side of the long cellular protrusions. Three different transport modes and velocities were identified: (i) Along actin filaments in the cytosol, nucleocapsids were transported at ∼200 nm/s; (ii) nucleocapsids migrated from one actin filament to another at ∼400 nm/s; and (iii) VP40-associated nucleocapsids moved inside filopodia at 100 nm/s. Unique insights into the spatiotemporal dynamics of nucleocapsids and their interaction with the cytoskeleton and motor proteins can lead to novel classes of antivirals that interfere with the trafficking and subsequent release of the Marburg virus from infected cells. PMID:23940347

  11. Live-cell imaging of Marburg virus-infected cells uncovers actin-dependent transport of nucleocapsids over long distances.

    PubMed

    Schudt, Gordian; Kolesnikova, Larissa; Dolnik, Olga; Sodeik, Beate; Becker, Stephan

    2013-08-27

    Transport of large viral nucleocapsids from replication centers to assembly sites requires contributions from the host cytoskeleton via cellular adaptor and motor proteins. For the Marburg and Ebola viruses, related viruses that cause severe hemorrhagic fevers, the mechanism of nucleocapsid transport remains poorly understood. Here we developed and used live-cell imaging of fluorescently labeled viral and host proteins to characterize the dynamics and molecular requirements of nucleocapsid transport in Marburg virus-infected cells under biosafety level 4 conditions. The study showed a complex actin-based transport of nucleocapsids over long distances from the viral replication centers to the budding sites. Only after the nucleocapsids had associated with the matrix viral protein VP40 at the plasma membrane were they recruited into filopodia and cotransported with host motor myosin 10 toward the budding sites at the tip or side of the long cellular protrusions. Three different transport modes and velocities were identified: (i) Along actin filaments in the cytosol, nucleocapsids were transported at ∼200 nm/s; (ii) nucleocapsids migrated from one actin filament to another at ∼400 nm/s; and (iii) VP40-associated nucleocapsids moved inside filopodia at 100 nm/s. Unique insights into the spatiotemporal dynamics of nucleocapsids and their interaction with the cytoskeleton and motor proteins can lead to novel classes of antivirals that interfere with the trafficking and subsequent release of the Marburg virus from infected cells.

  12. Long noncoding RNA EWSAT1-mediated gene repression facilitates Ewing sarcoma oncogenesis

    PubMed Central

    Marques Howarth, Michelle; Simpson, David; Ngok, Siu P.; Nieves, Bethsaida; Chen, Ron; Siprashvili, Zurab; Vaka, Dedeepya; Breese, Marcus R.; Crompton, Brian D.; Alexe, Gabriela; Hawkins, Doug S.; Jacobson, Damon; Brunner, Alayne L.; West, Robert; Mora, Jaume; Stegmaier, Kimberly; Khavari, Paul; Sweet-Cordero, E. Alejandro

    2014-01-01

    Chromosomal translocation that results in fusion of the genes encoding RNA-binding protein EWS and transcription factor FLI1 (EWS-FLI1) is pathognomonic for Ewing sarcoma. EWS-FLI1 alters gene expression through mechanisms that are not completely understood. We performed RNA sequencing (RNAseq) analysis on primary pediatric human mesenchymal progenitor cells (pMPCs) expressing EWS-FLI1 in order to identify gene targets of this oncoprotein. We determined that long noncoding RNA-277 (Ewing sarcoma–associated transcript 1 [EWSAT1]) is upregulated by EWS-FLI1 in pMPCs. Inhibition of EWSAT1 expression diminished the ability of Ewing sarcoma cell lines to proliferate and form colonies in soft agar, whereas EWSAT1 inhibition had no effect on other cell types tested. Expression of EWS-FLI1 and EWSAT1 repressed gene expression, and a substantial fraction of targets that were repressed by EWS-FLI1 were also repressed by EWSAT1. Analysis of RNAseq data from primary human Ewing sarcoma further supported a role for EWSAT1 in mediating gene repression. We identified heterogeneous nuclear ribonucleoprotein (HNRNPK) as an RNA-binding protein that interacts with EWSAT1 and found a marked overlap in HNRNPK-repressed genes and those repressed by EWS-FLI1 and EWSAT1, suggesting that HNRNPK participates in EWSAT1-mediated gene repression. Together, our data reveal that EWSAT1 is a downstream target of EWS-FLI1 that facilitates the development of Ewing sarcoma via the repression of target genes. PMID:25401475

  13. The effect of external non-driving factors, payment type and waiting and queuing on fatigue in long distance trucking.

    PubMed

    Williamson, Ann; Friswell, Rena

    2013-09-01

    The aim of this study was to explore the effects of external influences on long distance trucking, in particular, incentive-based remuneration systems and the need to wait or queue to load or unload on driver experiences of fatigue. Long distance truck drivers (n=475) were recruited at truck rest stops on the major transport corridors within New South Wales, Australia and asked to complete a survey by self-administration or interview. The survey covered demographics, usual working arrangements, details of the last trip and safety outcomes including fatigue experiences. On average drivers' last trip was over 2000 km and took 21.5 h to complete with an additional 6h of non-driving work. Incentive payments were associated with longer working hours, greater distances driven and higher fatigue for more drivers. Drivers required to wait in queues did significantly more non-driving work and experienced fatigue more often than those who did not. Drivers who were not paid to wait did the longest trips with average weekly hours above the legal working hours limits, had the highest levels of fatigue and the highest levels of interference by work with family life. In contrast, drivers who were paid to wait did significantly less work with shorter usual hours and shorter last trips. Multivariate analysis showed that incentive-based payment and unpaid waiting in queues were significant predictors of driver fatigue. The findings suggest that mandating payment of drivers for non-driving work including waiting would reduce the amount of non-driving work required for drivers and reduce weekly hours of work. In turn this would reduce driver fatigue and safety risk as well as enhancing the efficiency of the long distance road transport industry. Copyright © 2013 Elsevier Ltd. All rights reserved.

  14. Epidemic spreading in networks with nonrandom long-range interactions

    NASA Astrophysics Data System (ADS)

    Estrada, Ernesto; Kalala-Mutombo, Franck; Valverde-Colmeiro, Alba

    2011-09-01

    An “infection,” understood here in a very broad sense, can be propagated through the network of social contacts among individuals. These social contacts include both “close” contacts and “casual” encounters among individuals in transport, leisure, shopping, etc. Knowing the first through the study of the social networks is not a difficult task, but having a clear picture of the network of casual contacts is a very hard problem in a society of increasing mobility. Here we assume, on the basis of several pieces of empirical evidence, that the casual contacts between two individuals are a function of their social distance in the network of close contacts. Then, we assume that we know the network of close contacts and infer the casual encounters by means of nonrandom long-range (LR) interactions determined by the social proximity of the two individuals. This approach is then implemented in a susceptible-infected-susceptible (SIS) model accounting for the spread of infections in complex networks. A parameter called “conductance” controls the feasibility of those casual encounters. In a zero conductance network only contagion through close contacts is allowed. As the conductance increases the probability of having casual encounters also increases. We show here that as the conductance parameter increases, the rate of propagation increases dramatically and the infection is less likely to die out. This increment is particularly marked in networks with scale-free degree distributions, where infections easily become epidemics. Our model provides a general framework for studying epidemic spreading in networks with arbitrary topology with and without casual contacts accounted for by means of LR interactions.

  15. Facilitating participatory multilevel decision-making by using interactive mental maps.

    PubMed

    Pfeiffer, Constanze; Glaser, Stephanie; Vencatesan, Jayshree; Schliermann-Kraus, Elke; Drescher, Axel; Glaser, Rüdiger

    2008-11-01

    Participation of citizens in political, economic or social decisions is increasingly recognized as a precondition to foster sustainable development processes. Since spatial information is often important during planning and decision making, participatory mapping gains in popularity. However, little attention has been paid to the fact that information must be presented in a useful way to reach city planners and policy makers. Above all, the importance of visualisation tools to support collaboration, analytical reasoning, problem solving and decision-making in analysing and planning processes has been underestimated. In this paper, we describe how an interactive mental map tool has been developed in a highly interdisciplinary disaster management project in Chennai, India. We moved from a hand drawn mental maps approach to an interactive mental map tool. This was achieved by merging socio-economic and geospatial data on infrastructure, local perceptions, coping and adaptation strategies with remote sensing data and modern technology of map making. This newly developed interactive mapping tool allowed for insights into different locally-constructed realities and facilitated the communication of results to the wider public and respective policy makers. It proved to be useful in visualising information and promoting participatory decision-making processes. We argue that the tool bears potential also for health research projects. The interactive mental map can be used to spatially and temporally assess key health themes such as availability of, and accessibility to, existing health care services, breeding sites of disease vectors, collection and storage of water, waste disposal, location of public toilets or defecation sites.

  16. Temporal and geographic patterns of kinship structure in common dolphins (Delphinus delphis) suggest site fidelity and female-biased long-distance dispersal.

    PubMed

    Ball, Laura; Shreves, Kypher; Pilot, Małgorzata; Moura, André E

    2017-01-01

    Social structure plays a crucial role in determining a species' dispersal patterns and genetic structure. Cetaceans show a diversity of social and mating systems, but their effects on dispersal and genetic structure are not well known, in part because of technical difficulties in obtaining robust observational data. Here, we combine genetic profiling and GIS analysis to identify patterns of kin distribution over time and space, to infer mating structure and dispersal patterns in short-beaked common dolphins ( Delphinus delphis ). This species is highly social, and exhibits weak spatial genetic structure in the Northeast Atlantic and Mediterranean Sea, thought to result from fluid social structure and low levels of site fidelity. We found that although sampled groups were not composed of closely related individuals, close kin were frequently found in the same geographic location over several years. Our results suggest that common dolphin exhibits some level of site fidelity, which could be explained by foraging for temporally varying prey resource in areas familiar to individuals. Dispersal from natal area likely involves long-distance movements of females, as males are found more frequently than females in the same locations as their close kin. Long-distance dispersal may explain the near panmixia observed in this species. By analysing individuals sampled in the same geographic location over multiple years, we avoid caveats associated with divergence-based methods of inferring sex-biased dispersal. We thus provide a unique perspective on this species' social structure and dispersal behaviour, and how it relates to the observed low levels of population genetic structure in European waters. Movement patterns and social interactions are aspects of wild animal's behaviour important for understanding their ecology. However, tracking these behaviours directly can be very challenging in wide-ranging species such as whales and dolphins. In this study, we used genetic

  17. Distance to High-Voltage Power Lines and Risk of Childhood Leukemia – an Analysis of Confounding by and Interaction with Other Potential Risk Factors

    PubMed Central

    Pedersen, Camilla; Bräuner, Elvira V.; Rod, Naja H.; Albieri, Vanna; Andersen, Claus E.; Ulbak, Kaare; Hertel, Ole; Johansen, Christoffer; Schüz, Joachim; Raaschou-Nielsen, Ole

    2014-01-01

    We investigated whether there is an interaction between distance from residence at birth to nearest power line and domestic radon and traffic-related air pollution, respectively, in relation to childhood leukemia risk. Further, we investigated whether adjusting for potential confounders alters the association between distance to nearest power line and childhood leukemia. We included 1024 cases aged <15, diagnosed with leukemia during 1968–1991, from the Danish Cancer Registry and 2048 controls randomly selected from the Danish childhood population and individually matched by gender and year of birth. We used geographical information systems to determine the distance between residence at birth and the nearest 132–400 kV overhead power line. Concentrations of domestic radon and traffic-related air pollution (NOx at the front door) were estimated using validated models. We found a statistically significant interaction between distance to nearest power line and domestic radon regarding risk of childhood leukemia (p = 0.01) when using the median radon level as cut-off point but not when using the 75th percentile (p = 0.90). We found no evidence of an interaction between distance to nearest power line and traffic-related air pollution (p = 0.73). We found almost no change in the estimated association between distance to power line and risk of childhood leukemia when adjusting for socioeconomic status of the municipality, urbanization, maternal age, birth order, domestic radon and traffic-related air pollution. The statistically significant interaction between distance to nearest power line and domestic radon was based on few exposed cases and controls and sensitive to the choice of exposure categorization and might, therefore, be due to chance. PMID:25259740

  18. Context and meter enhance long-range planning in music performance

    PubMed Central

    Mathias, Brian; Pfordresher, Peter Q.; Palmer, Caroline

    2015-01-01

    Neural responses demonstrate evidence of resonance, or oscillation, during the production of periodic auditory events. Music contains periodic auditory events that give rise to a sense of beat, which in turn generates a sense of meter on the basis of multiple periodicities. Metrical hierarchies may aid memory for music by facilitating similarity-based associations among sequence events at different periodic distances that unfold in longer contexts. A fundamental question is how metrical associations arising from a musical context influence memory during music performance. Longer contexts may facilitate metrical associations at higher hierarchical levels more than shorter contexts, a prediction of the range model, a formal model of planning processes in music performance (Palmer and Pfordresher, 2003; Pfordresher et al., 2007). Serial ordering errors, in which intended sequence events are produced in incorrect sequence positions, were measured as skilled pianists performed musical pieces that contained excerpts embedded in long or short musical contexts. Pitch errors arose from metrically similar positions and further sequential distances more often when the excerpt was embedded in long contexts compared to short contexts. Musicians’ keystroke intensities and error rates also revealed influences of metrical hierarchies, which differed for performances in long and short contexts. The range model accounted for contextual effects and provided better fits to empirical findings when metrical associations between sequence events were included. Longer sequence contexts may facilitate planning during sequence production by increasing conceptual similarity between hierarchically associated events. These findings are consistent with the notion that neural oscillations at multiple periodicities may strengthen metrical associations across sequence events during planning. PMID:25628550

  19. Interactive Distance Learning Technology and Connectedness

    ERIC Educational Resources Information Center

    Devlin, Brian; Feraud, Peter; Anderson, Alan

    2008-01-01

    This three-part paper discusses how the contemporary use of computers in distance education is helping to connect students from our rural communities, whether they are located at pastoral stations, remote community schools or are on the road, travelling with parents or carers. The paper is in a sense organised like a sandwich, with technical…

  20. Evaluation on Cost Overrun Risks of Long-distance Water Diversion Project Based on SPA-IAHP Method

    NASA Astrophysics Data System (ADS)

    Yuanyue, Yang; Huimin, Li

    2018-02-01

    Large investment, long route, many change orders and etc. are main causes for costs overrun of long-distance water diversion project. This paper, based on existing research, builds a full-process cost overrun risk evaluation index system for water diversion project, apply SPA-IAHP method to set up cost overrun risk evaluation mode, calculate and rank weight of every risk evaluation indexes. Finally, the cost overrun risks are comprehensively evaluated by calculating linkage measure, and comprehensive risk level is acquired. SPA-IAHP method can accurately evaluate risks, and the reliability is high. By case calculation and verification, it can provide valid cost overrun decision making information to construction companies.