Future of ePix detectors for high repetition rate FELs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Blaj, G., E-mail: blaj@slac.stanford.edu; Caragiulo, P.; Carini, G.

2016-07-27

Free-electron lasers (FELs) made the imaging of atoms and molecules in motion possible, opening new science opportunities with high brilliance, ultra-short x-ray laser pulses at up to 120 Hz. Some new or upgraded FEL facilities will operate at greatly increased pulse rates (kHz to MHz), presenting additional requirements on detection. We will present the ePix platform for x-ray detectors and the current status of the ePix detectors: ePix100 for low noise applications, ePix10k for high dynamic range applications, and ePixS for spectroscopic applications. Then we will introduce the plans to match the ePix detectors with the requirements of currently plannedmore » high repetition rate FELs (mainly readout speed and energy range).« less

Influence of nonlinear effects on statistical properties of the radiation from SASE FEL

NASA Astrophysics Data System (ADS)

Saldin, E. L.; Schneidmiller, E. A.; Yurkov, M. V.

1998-02-01

The paper presents analysis of statistical properties of the radiation from self-amplified spontaneous emission (SASE) free-electron laser operating in nonlinear mode. The present approach allows one to calculate the following statistical properties of the SASE FEL radiation: time and spectral field correlation functions, distribution of the fluctuations of the instantaneous radiation power, distribution of the energy in the electron bunch, distribution of the radiation energy after monochromator installed at the FEL amplifier exit and the radiation spectrum. It has been observed that the statistics of the instantaneous radiation power from SASE FEL operating in the nonlinear regime changes significantly with respect to the linear regime. All numerical results presented in the paper have been calculated for the 70 nm SASE FEL at the TESLA Test Facility under construction at DESY.

Parameter design considerations for an oscillator IR-FEL

NASA Astrophysics Data System (ADS)

Jia, Qi-Ka

2017-01-01

An infrared oscillator FEL user facility will be built at the National Synchrotron Radiation Laboratory at in Hefei, China. In this paper, the parameter design of the oscillator FEL is discussed, and some original relevant approaches and expressions are presented. Analytic formulae are used to estimate the optical field gain and saturation power for the preliminary design. By considering both physical and technical constraints, the relation of the deflection parameter K to the undulator period is analyzed. This helps us to determine the ranges of the magnetic pole gap, the electron energy and the radiation wavelength. The relations and design of the optical resonator parameters are analyzed. Using dimensionless quantities, the interdependences between the radii of curvature of the resonator mirror and the various parameters of the optical resonator are clearly demonstrated. The effect of the parallel-plate waveguide is analyzed for the far-infrared oscillator FEL. The condition of the necessity of using a waveguide and the modified filling factor in the case of the waveguide are given, respectively. Supported by National Nature Science Foundation of China (21327901, 11375199)

UCSB FEL user-mode adaption project. Final report, 1 Jan 86-31 Dec 90

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jaccarino, V.

1992-04-14

This research sponsored by the SDIO Biomedical and Materials Sciences FEL Program held the following objectives. Provide a facility in which in-house and outside user research in the materials and biological sciences can be carried out in the Far Infrared using-the unique properties of the UCSB electrostatic accelerator-driven FEL. Develop and implement new FEL concepts and FIR technology and encourage the transfer and application of this research. Train graduate students, post doctoral researchers and technical personnel in varied aspects of scientific user disciplines, FEL science and FIR technology in a cooperative, interdisciplinary environment. In summary, a free electron laser facilitymore » has been developed which is operational from 200 GH z, (6.6 cm -1), to 4.8 THz, (160 cm-1) tunable under computer control and able to deliver kilowatts of millimeter wave and far-infrared power. This facility has a well equipped user lab that has been used to perform ground breaking experiments in scientific areas as diverse as bio-physics. Nine graduate students and post doctoral researchers have been trained in the operation, use and application of these free-electron lasers.« less

INITIAL GAIN MEASUREMENTS OF A 800 NM SASE FEL, VISA.

DOE Office of Scientific and Technical Information (OSTI.GOV)

FRIGOLA,P.; MUROKH,A.; ET AL

2000-08-13

The VISA (Visible to Infrared SASE Amplifier) FEL is designed to obtain high gain at a radiation wavelength of 800nm. The FEL uses the high brightness electron beam of the Accelerator Test Facility (ATF), with energy of 72MeV. VISA uses a novel, 4 m long, strong focusing undulator with a gap of 6mm and a period of 1.8cm. To obtain large gain the beam and undulator axis have to be aligned to better than 50{micro}m. Results from initial measurements on the alignment, gain, and spectrum will be presented and compared to theoretical calculations and simulations.

Experimental setups for FEL-based four-wave mixing experiments at FERMI

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bencivenga, Filippo; Zangrando, Marco; Svetina, Cristian

2016-01-01

The recent advent of free-electron laser (FEL) sources is driving the scientific community to extend table-top laser research to shorter wavelengths adding elemental selectivity and chemical state specificity. Both a compact setup (mini-TIMER) and a separate instrument (EIS-TIMER) dedicated to four-wave-mixing (FWM) experiments has been designed and constructed, to be operated as a branch of the Elastic and Inelastic Scattering beamline: EIS. The FWM experiments that are planned at EIS-TIMER are based on the transient grating approach, where two crossed FEL pulses create a controlled modulation of the sample excitations while a third time-delayed pulse is used to monitor themore » dynamics of the excited state. This manuscript describes such experimental facilities, showing the preliminary results of the commissioning of the EIS-TIMER beamline, and discusses original experimental strategies being developed to study the dynamics of matter at the fs–nm time–length scales. In the near future such experimental tools will allow more sophisticated FEL-based FWM applications, that also include the use of multiple and multi-color FEL pulses.« less

Experimental setups for FEL-based four-wave mixing experiments at FERMI

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bencivenga, Filippo; Zangrando, Marco; Svetina, Cristian

The recent advent of free-electron laser (FEL) sources is driving the scientific community to extend table-top laser research to shorter wavelengths adding elemental selectivity and chemical state specificity. Both a compact setup (mini-TIMER) and a separate instrument (EIS-TIMER) dedicated to four-wave-mixing (FWM) experiments has been designed and constructed, to be operated as a branch of the Elastic and Inelastic Scattering beamline: EIS. The FWM experiments that are planned at EIS-TIMER are based on the transient grating approach, where two crossed FEL pulses create a controlled modulation of the sample excitations while a third time-delayed pulse is used to monitor themore » dynamics of the excited state. This manuscript describes such experimental facilities, showing the preliminary results of the commissioning of the EIS-TIMER beamline, and discusses original experimental strategies being developed to study the dynamics of matter at the fs–nm time–length scales. In the near future such experimental tools will allow more sophisticated FEL-based FWM applications, that also include the use of multiple and multi-color FEL pulses.« less

Harmonic cascade FEL designs for LUX

DOE Office of Scientific and Technical Information (OSTI.GOV)

Penn, G.; Reinsch, M.; Wurtele, J.

LUX is a design concept for an ultrafast X-ray science facility, based on an electron beam accelerated to GeV energies in are circulating linac. Included in the design are short duration (200 fs or shorter FWHM) light sources using multiple stages of higher harmonic generation, seeded by a 200-250 nm laser of similar duration. This laser modulates the energy of a group of electrons within the electron bunch; this section of the electron bunch then produces radiation at a higher harmonic after entering a second, differently tuned undulator. Repeated stages in a cascade yield increasing photon energies up to 1more » keV. Most of the undulators in the cascade operate in the low-gain FEL regime. Harmonic cascades have been designed for each pass of the recirculating linac up to a final electron beam energy of 3.1 GeV. For a given cascade, the photon energy can be selected over a wide range by varying the seed laser frequency and the field strength in the undulators. We present simulation results using the codes GENESIS and GINGER, as well as the results of analytical models which predict FEL performance. We discuss lattice considerations pertinent for harmonic cascade FELs, as well as sensitivity studies and requirements on the electron beam.« less

DC High Voltage Conditioning of Photoemission Guns at Jefferson Lab FEL

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hernandez-Garcia, C.; Benson, S. V.; Biallas, G.

2009-08-04

DC high voltage photoemission electron guns with GaAs photocathodes have been used to produce polarized electron beams for nuclear physics experiments for about 3 decades with great success. In the late 1990s, Jefferson Lab adopted this gun technology for a free electron laser (FEL), but to assist with high bunch charge operation, considerably higher bias voltage is required compared to the photoguns used at the Jefferson Lab Continuous Electron Beam Accelerator Facility. The FEL gun has been conditioned above 400 kV several times, albeit encountering non-trivial challenges with ceramic insulators and field emission from electrodes. Recently, high voltage processing withmore » krypton gas was employed to process very stubborn field emitters. This work presents a summary of the high voltage techniques used to high voltage condition the Jefferson Lab FEL photoemission gun.« less

In-pixel conversion with a 10 bit SAR ADC for next generation X-ray FELs

NASA Astrophysics Data System (ADS)

Lodola, L.; Batignani, G.; Benkechkache, M. A.; Bettarini, S.; Casarosa, G.; Comotti, D.; Dalla Betta, G. F.; Fabris, L.; Forti, F.; Grassi, M.; Latreche, S.; Malcovati, P.; Manghisoni, M.; Mendicino, R.; Morsani, F.; Paladino, A.; Pancheri, L.; Paoloni, E.; Ratti, L.; Re, V.; Rizzo, G.; Traversi, G.; Vacchi, C.; Verzellesi, G.; Xu, H.

2016-07-01

This work presents the design of an interleaved Successive Approximation Register (SAR) ADC, part of the readout channel for the PixFEL detector. The PixFEL project aims at substantially advancing the state-of-the-art in the field of 2D X-ray imaging for applications at the next generation Free Electron Laser (FEL) facilities. For this purpose, the collaboration is developing the fundamental microelectronic building blocks for the readout channel. This work focuses on the design of the ADC carried out in a 65 nm CMOS technology. To obtain a good tradeoff between power consumption, conversion speed and area occupation, an interleaved SAR ADC architecture was adopted.

The FERMIatElettra FEL Photon Transport System

NASA Astrophysics Data System (ADS)

Zangrando, M.; Cudin, I.; Fava, C.; Godnig, R.; Kiskinova, M.; Masciovecchio, C.; Parmigiani, F.; Rumiz, L.; Svetina, C.; Turchet, A.; Cocco, D.

2010-06-01

The FERMI@Elettra free electron laser (FEL) user facility is under construction at Sincrotrone Trieste (Italy), and it will be operative in late 2010. It is based on a seeded scheme providing an almost perfect transform-limited and fully spatially coherent photon beam. FERMI@Elettra will cover the wavelength range 100 to 3 nm with the fundamental harmonics, and down to 1 nm with higher harmonics. We present the layout of the photon beam transport system that includes: the first common part providing on-line and shot-to-shot beam diagnostics, called PADReS (Photon Analysis Delivery and Reduction System), and 3 independent beamlines feeding the experimental stations. Particular emphasis is given to the solutions adopted to preserve the wavefront, and to avoid damage on the different optical elements. Peculiar FEL devices, not common in the Synchrotron Radiation facilities, are described in more detail, e.g. the online photon energy spectrometer measuring shot-by-shot the spectrum of the emitted radiation, the beam splitting and delay line system dedicated to cross/auto correlation and pump-probe experiments, and the wavefront preserving active optics adapting the shape and size of the focused spot to meet the needs of the different experiments.

Lattice Design for a High-Power Infrared FEL

NASA Astrophysics Data System (ADS)

Douglas, D. R.

1997-05-01

A 1 kW infrared FEL, funded by the U.S. Navy, is under construction at Jefferson Lab. This device will be driven by a compact, 42 MeV, 5 mA, energy-recovering, CW SRF-based linear accelerator to produce light in the 3-6.6 μm range. The machine concept comprises a 10 MeV injector, a linac based on a single high-gradient Jefferson Lab accelerator cryomodule, a wiggler and optical cavity, and an energy-recovery recirculation arc. Energy recovery limits cost and technical risk by reducing the RF power requirements in the driver accelerator. Following deceleration to 10 MeV, the beam is dumped. Stringent phase space requirements at the wiggler, low beam energy, and high beam current subject the accelerator lattice to numerous constraints. Principal considerations include: transport and delivery to the FEL of a high-quality, high-current beam; the impact of coherent synchrotron radiation (CSR) during beam recirculation transport; beam optics aberration control, to provide low-loss energy-recovery transport of a 5% relative momentum spread, high-current beam; attention to possible beam breakup (BBU) instabilities in the recirculating accelerator; and longitudinal phase space management during beam transport, to optimize RF drive system control during energy recovery and FEL operation. The presentation will address the design process and design solution for an accelerator transport lattice that meets the requirements imposed by these physical phenomena and operational necessities.

Duke storage rink UV/VUV FEL: Status and prospects

DOE Office of Scientific and Technical Information (OSTI.GOV)

Litvinenko, V.N.; Burnham, B.; Madey, J.M.J.

1995-12-31

The 1 GeV Duke storage ring was successfully commissioned with parameters exceeding initial specification. The OK-4 FEL has arrived at the Duke FEL laboratory from the Novosibirsk Institute of Nuclear Physics. The OK-4 installation and commissioning is in progress. In this paper we describe the up-to-date status of the Duke storage ring and the OK-4 FEL. The projected performance of the OK-4 UV/VUV FEL is presented based on the electron beam parameters achieved. Initial plans to operate the OK-4 UV/VUV FEL at the Duke 1 GeV storage ring are outlined. Future plans and prospects of both the OK-4 FEL andmore » the Duke storage ring are discussed.« less

Start-Up of FEL Oscillator from Shot Noise

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kumar, V.; Krishnagopal, S.; Fawley, W.M.

In free-electron laser (FEL) oscillators, as inself-amplified spontaneous emission (SASE) FELs, the buildup of cavitypower starts from shot noise resulting from the discreteness ofelectronic charge. It is important to do the start-up analysis for thebuild-up of cavity power in order to fix the macropulse width from theelectron accelerator such that the system reaches saturation. In thispaper, we use the time-dependent simulation code GINGER [1]toperformthis analysis. We present results of this analysis for theparameters of the Compact Ultrafast TErahertz FEL (CUTE-FEL) [2]beingbuilt atRRCAT.

Fused rock from Köfels, Tyrol

USGS Publications Warehouse

Milton, Daniel J.

1964-01-01

The vesicular glass from Köfels, Tyrol, contains grains of quartz that have been partially melted but not dissolved in the matrix glass. This phenomenon has been observed in similar glasses formed by friction along a thrust fault and by meteorite impact, but not in volcanic glasses. The explosion of a small nuclear device buried behind a steep slope produced a geologic structure that is a good small-scale model of that at Köfels. Impact of a large meteorite would have an effect analogous to that of a subsurface nuclear explosion and is the probable cause of the Köfels feature.

Design and realization of the optical and electron beam alignment system for the HUST-FEL oscillator

NASA Astrophysics Data System (ADS)

Fu, Q.; Tan, P.; Liu, K. F.; Qin, B.; Liu, X.

2018-06-01

A Free Electron Laser(FEL) oscillator with radiation wavelength at 30-100 μ m is under commissioning at Huazhong University of Science and Technology (HUST). This work presents the schematic design and realization procedures for the optical and beam alignment system in the HUST FEL facility. The optical cavity misalignment effects are analyzed with the code OPC + Genesis 1.3, and the tolerance of misalignment is proposed with the simulation result. Depending on undulator mechanical benchmarks, a laser indicating system has been built up as reference datum. The alignment of both optical axis and beam trajectory were achieved by this alignment system.

Novel active signal compression in low-noise analog readout at future X-ray FEL facilities

NASA Astrophysics Data System (ADS)

Manghisoni, M.; Comotti, D.; Gaioni, L.; Lodola, L.; Ratti, L.; Re, V.; Traversi, G.; Vacchi, C.

2015-04-01

This work presents the design of a low-noise front-end implementing a novel active signal compression technique. This feature can be exploited in the design of analog readout channels for application to the next generation free electron laser (FEL) experiments. The readout architecture includes the low-noise charge sensitive amplifier (CSA) with dynamic signal compression, a time variant shaper used to process the signal at the preamplifier output and a 10-bit successive approximation register (SAR) analog-to-digital converter (ADC). The channel will be operated in such a way to cope with the high frame rate (exceeding 1 MHz) foreseen for future XFEL machines. The choice of a 65 nm CMOS technology has been made in order to include all the building blocks in the target pixel pitch of 100 μm. This work has been carried out in the frame of the PixFEL Project funded by the Istituto Nazionale di Fisica Nucleare (INFN), Italy.

BEAM OPTIMIZATION STUDY FOR AN X-RAY FEL OSCILLATOR AT THE LCLS-II

DOE Office of Scientific and Technical Information (OSTI.GOV)

Qin, Weilun; Huang, S.; Liu, K.X.

2016-06-01

The 4 GeV LCLS-II superconducting linac with high repetition beam rate enables the possibility to drive an X-Ray FEL oscillator at harmonic frequencies *. Compared to the regular LCLS-II machine setup, the oscillator mode requires a much longer bunch length with a relatively lower current. Also a flat longitudinal phase space distribution is critical to maintain the FEL gain since the X-ray cavity has extremely narrow bandwidth. In this paper, we study the longitudinal phase space optimization including shaping the initial beam from the injector and optimizing the bunch compressor and dechirper parameters. We obtain a bunch with a flatmore » energy chirp over 400 fs in the core part with current above 100 A. The optimization was based on LiTrack and Elegant simulations using LCLS-II beam parameters.« less

Compact single-pass X-ray FEL with harmonic multiplication cascades

NASA Astrophysics Data System (ADS)

Zhukovsky, K.

2018-07-01

The generation of X-ray radiation in cascaded single-pass free electron laser (FEL), which amplifies high harmonics of a two-frequency undulator, is studied. Power dynamics of FEL harmonics is explored with the help of the phenomenological model of a single pass FEL. The model describes both linear and non-linear harmonic generation, starting from a coherent seed laser and initial shot noise with account for main loss factors for each harmonic in each cascade individually: the energy spread and beam divergence, the coupling losses between FEL cascades, the diffraction etc. The model was validated with the experiment and with relevant 3-D simulations. It is employed for modeling the cascaded FELs with harmonic multiplication and analyzing the evolution of FEL harmonic power with the aim to obtain the maximum high harmonic power in the X-ray band at the shortest possible FEL length with the lowest possible seed frequency. The advantages of two-frequency undulators in HGHG FELs are elucidated. The requirements for the electron beam are studied; the need for low energy spread is evidenced: our evaluations yield σe < 2 × 10-4. Several cascaded HGHG FELs with two-frequency undulators are modeled. Generation of soft X-ray radiation at λ = 2 . 71 nm, reaching ∼50 MW power with I0 ∼ 100 A in a cascaded FEL at just 40 m with 13.51 nm seed, matching peak reflectivity of Mo/Si, is demonstrated. The generation of 40 MW radiation power at λ = 2 . 27 nm with the beam current I0 ∼ 100 A, energy E = 950 MeV and the energy spread σe = 2 × 10-4 is studied, using second and third harmonics in three-stage 45 m long FEL. The multistage FEL is modeled for generating radiation in nanometer band: ∼40 MW power at λ ∼ 2 . 6 nm with I0 ∼ 175 A current in just ∼40 m long FEL with commercially available F2 excimer UV laser seed at 157 nm. The peak radiation power rises to ∼0.5 GW for ∼1 kA beam current.

FEL investigations of energy transfer in condensed phase systems

NASA Astrophysics Data System (ADS)

Henderson, Don O.; Mu, Richard; Silberman, Enrique; Johnson, J. B.; Edwards, Glenn S.

1993-07-01

The vibrational dynamics of O-H groups in fused silica have been examined by a time- resolved pump-probe technique using the Vanderbilt Free Electron Laser (FEL). We consider two effects, local heating and transient thermal lensing, which can influence measured T1 values in one color pump-probe measurements. The dependence of these two effects on both the micropulse spacing and the total number of micropulses delivered to the sample are analyzed in detail for the O-H/SiO2 system. The results indicate that transient thermal lensing can significantly influence the measured probe signal. The local heating may cause thermally induced changes in the ground state population of the absorber, thereby complicating the analysis of the relaxation dynamics.

Direct experimental observation of the gas density depression effect using a two-bunch X-ray FEL beam.

PubMed

Feng, Y; Schafer, D W; Song, S; Sun, Y; Zhu, D; Krzywinski, J; Robert, A; Wu, J; Decker, F J

2018-01-01

The experimental observation of the depression effect in gas devices designed for X-ray free-electron lasers (FELs) is reported. The measurements were carried out at the Linac Coherent Light Source using a two-bunch FEL beam at 6.5 keV with 122.5 ns separation passing through an argon gas cell. The relative intensities of the two pulses of the two-bunch beam were measured, after and before the gas cell, from X-ray scattering off thin targets by using fast diodes with sufficient temporal resolution. At a cell pressure of 140 hPa, it was found that the after-to-before ratio of the intensities of the second pulse was about 17% ± 6% higher than that of the first pulse, revealing lower effective attenuation of the gas cell due to heating by the first pulse and subsequent gas density reduction in the beam path. This measurement is important in guiding the design and/or mitigating the adverse effects in gas devices for high-repetition-rate FELs such as the LCLS-II and the European XFEL or other future high-repetition-rate upgrades to existing FEL facilities.

Direct experimental observation of the gas density depression effect using a two-bunch X-ray FEL beam

DOE PAGES

Feng, Y.; Schafer, D. W.; Song, S.; ...

2018-01-01

The experimental observation of the depression effect in gas devices designed for X-ray free-electron lasers (FELs) is reported. The measurements were carried out at the Linac Coherent Light Source using a two-bunch FEL beam at 6.5 keV with 122.5 ns separation passing through an argon gas cell. The relative intensities of the two pulses of the two-bunch beam were measured, after and before the gas cell, from X-ray scattering off thin targets by using fast diodes with sufficient temporal resolution. At a cell pressure of 140 hPa, it was found that the after-to-before ratio of the intensities of the secondmore » pulse was about 17% ± 6% higher than that of the first pulse, revealing lower effective attenuation of the gas cell due to heating by the first pulse and subsequent gas density reduction in the beam path. Furthermore, this measurement is important in guiding the design and/or mitigating the adverse effects in gas devices for high-repetition-rate FELs such as the LCLS-II and the European XFEL or other future high-repetition-rate upgrades to existing FEL facilities.« less

Direct experimental observation of the gas density depression effect using a two-bunch X-ray FEL beam

DOE Office of Scientific and Technical Information (OSTI.GOV)

Feng, Y.; Schafer, D. W.; Song, S.

The experimental observation of the depression effect in gas devices designed for X-ray free-electron lasers (FELs) is reported. The measurements were carried out at the Linac Coherent Light Source using a two-bunch FEL beam at 6.5 keV with 122.5 ns separation passing through an argon gas cell. The relative intensities of the two pulses of the two-bunch beam were measured, after and before the gas cell, from X-ray scattering off thin targets by using fast diodes with sufficient temporal resolution. At a cell pressure of 140 hPa, it was found that the after-to-before ratio of the intensities of the secondmore » pulse was about 17% ± 6% higher than that of the first pulse, revealing lower effective attenuation of the gas cell due to heating by the first pulse and subsequent gas density reduction in the beam path. Furthermore, this measurement is important in guiding the design and/or mitigating the adverse effects in gas devices for high-repetition-rate FELs such as the LCLS-II and the European XFEL or other future high-repetition-rate upgrades to existing FEL facilities.« less

Bunch Length Measurements at JLab FEL

DOE Office of Scientific and Technical Information (OSTI.GOV)

P. Evtushenko; J. L. Coleman; K. Jordan

2006-09-01

The JLab FEL is routinely operated with sub-picosecond bunches. The short bunch length is important for high gain of the FEL. Coherent transition radiation has been used for the bunch length measurements for many years. This diagnostic can be used only in the pulsed beam mode. It is our goal to run FEL with CW beam and 74.85 MHz micropulse repetition rate. Hence it is very desirable to have the possibility of doing the bunch length measurements when running CW beam with any micropulse frequency. We use a Fourier transform infrared interferometer, which is essentially a Michelson interferometer, to measuremore » the spectrum of the coherent synchrotron radiation generated in the last dipole of the magnetic bunch compressor upstream of the FEL wiggler. This noninvasive diagnostic provides the bunch length measurements for CW beam operation at any micropulse frequency. We also compare the measurements made with the help of the FTIR interferometer with the data obtained by the Martin-Puplett interferometer. Results of the two diagnostics are usually agree within 15%. Here we present a description of the experimental setup, data evaluation procedure and results of the beam measurements.« less

Efficiency Optimization for FEL Oscillators,

DTIC Science & Technology

1987-12-01

I 7 -ŕvle 3IIATIONCIFOR FEL OSCILLATORS(U) MARYLAND i/1’ UNIV COLLEGE PARK LAS FOR PLASMIA AND FUSION ENERGY STUDIES A SERBETO ET AL DEC 87 UMLPF-88...University of Maryland, By3 f *O- 0Laboratory for Plasrra and Fusion Energy Studies D i~ Avciil adi r "UnOUIO SAEMNT A APPrOVed for public reloe...Distribution Unlimited EFFICIENCY OPTIMIZATION FOR FEL OSCILLATORS A. Serbeto, B. Levush, and T. M. Antonsen, Jr. Laboratory for Plasma and Fusion Energy Studies

An update on molecular cat allergens: Fel d 1 and what else? Chapter 1: Fel d 1, the major cat allergen.

PubMed

Bonnet, B; Messaoudi, K; Jacomet, F; Michaud, E; Fauquert, J L; Caillaud, D; Evrard, B

2018-01-01

Cats are the major source of indoor inhalant allergens after house dust mites. The global incidence of cat allergies is rising sharply, posing a major public health problem. Ten cat allergens have been identified. The major allergen responsible for symptoms is Fel d 1, a secretoglobin and not a lipocalin, making the cat a special case among mammals. Given its clinical predominance, it is essential to have a good knowledge of this allergenic fraction, including its basic structure, to understand the new exciting diagnostic and therapeutic applications currently in development. The recent arrival of the component-resolved diagnosis, which uses molecular allergens, represents a unique opportunity to improve our understanding of the disease. Recombinant Fel d 1 is now available for in vitro diagnosis by the anti-Fel d 1 specific IgE assay. The first part of the review will seek to describe the recent advances related to Fel d 1 in terms of positive diagnosis and assessment of disease severity. In daily practice, anti-Fel d 1 IgE tend to replace those directed against the overall extract but is this attitude justified? We will look at the most recent arguments to try to answer this question. In parallel, a second revolution is taking place thanks to molecular engineering, which has allowed the development of various forms of recombinant Fel d 1 and which seeks to modify the immunomodulatory properties of the molecule and thus the clinical history of the disease via various modalities of anti-Fel d 1-specific immunotherapy. We will endeavor to give a clear and practical overview of all these trends.

Free-electron laser spectroscopy in biology, medicine, and materials science; Proceedings of the Meeting, Los Angeles, CA, Jan. 22, 1993

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schwettman, H.A.

1993-01-01

Various papers on FEL spectroscopy in biology, medicine, and materials science are presented. Individual topics addressed include: Vanderbilt University FEL Center, FIR FEL facility at the University of California/Santa Barbara, FEL research facilities and opportunities at Duke, facilities at the Stanford Picosecond FEL Center, FIR nonlinear response of electrons in semiconductor nanostructures, FIR harmonic generation from semiconductor heterostructures, intrinsic response times of double-barrier resonant tunneling diodes at tetrahertz frequencies, semiconductor spectroscopy and ablation processes with the Vanderbilt FEL. Also discussed are: picosecond nonlinear optics in semiconductor quantum wells with the SCA FEL, excitation spectroscopy of thin-film disordered semiconductors, biophysical applicationmore » of FELs, FEL investigation of energy transfer in condensed phase systems, probing protein photochemistry and dynamics with ultrafast infrared spectroscopy, plasma ablation of hard tissues by FEL, FEL irradiation of the cornea.« less

Electron Beam Diagnostics Of The JLAB UV FEL

DOE Office of Scientific and Technical Information (OSTI.GOV)

Evtushenko, Pavel; Benson, Stephen; Biallas, George

2011-03-01

In this contribution we describe various systems and aspects of the electron beam diagnostics of the JLab UV FEL. The FEL is installed on a new bypass beam line at the existing 10 kW IR Upgrade FEL. Here, we describe a set of the following systems. A combination of OTR and phosphor viewers is used for measurements of the transverse beam profile, transverse emittance, and Twiss parameters. This system is also used for alignment of the optical cavity of the UV oscillator and to ensure the overlap between the electron beam and optical mode in the FEL wiggler. A systemmore » of beam position monitors equipped with log-amp based BPM electronics. Bunch length on the order of 120 fs RMS is measured with the help of a modified Martin-Puplett interferometer. The longitudinal transfer function measurement system is used to set up bunch compression in an optimal way, such that the LINAC RF curvature is compensated using only higher order magnetic elements of the beam transport. This set of diagnostic systems made a significant contribution in achieving first lasing of the FEL after only about 60 hours of beam operation.« less

40 CFR 1033.750 - Changing a locomotive's FEL at remanufacture.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Changing a locomotive's FEL at... Certification § 1033.750 Changing a locomotive's FEL at remanufacture. Locomotives are generally required to be... revised FEL for the remainder of their service lives, unless it is changed again under this section during...

40 CFR 1033.750 - Changing a locomotive's FEL at remanufacture.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 33 2011-07-01 2011-07-01 false Changing a locomotive's FEL at... Certification § 1033.750 Changing a locomotive's FEL at remanufacture. Locomotives are generally required to be... revised FEL for the remainder of their service lives, unless it is changed again under this section during...

A button - type beam position monitor design for TARLA facility

NASA Astrophysics Data System (ADS)

Gündoǧan, M. Tural; Kaya, ć.; Yavaş, Ö.

2016-03-01

Turkish Accelerator and Radiation Laboratory in Ankara (TARLA) facility is proposed as an IR FEL and Bremsstrahlung facility as the first facility of Turkish Accelerator Center (TAC). TARLA is essentially proposed to generate oscillator mode FEL in 3-250 microns wavelengths range, will consist of normal conducting injector system with 250 keV beam energy, two superconducting RF accelerating modules in order to accelerate the beam 15-40 MeV. The TARLA facility is expected to provide two modes, Continuous wave (CW) and pulsed mode. Longitudinal electron bunch length will be changed between 1 and 10 ps. The bunch charge will be limited by 77pC. The design of the Button-type Beam Position Monitor for TARLA IR FEL is studied to operate in 1.3 GHz. Mechanical antenna design and simulations are completed considering electron beam parameters of TARLA. Ansoft HFSS and CST Particle Studio is used to compare with results of simulations.

Numerical study of the 3-D effect on FEL performance and its application to the APS LEUTL FEL

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chae, Y.C.

A Low-Energy Undulator Test Line (LEUTL) is under construction at the Advanced Photon Source (APS). In LEUTL periodic focusing is provided by external quadrupoles. This results in an elliptical beam with its betatron oscillation envelope varying along the undulators. The free-electron laser (FEL) interaction with such a beam will exhibit truly 3-D effects. Thus the investigation of 3-D effects is important in optimizing the FEL performance. The programs GINGER and TDA3D, coupled with theoretically known facts, have been used for this purpose. Both programs are fully 3-D in moving the particle, but model the interaction between particles and axially symmetricmore » electromagnetic waves. Even though TDA3D can include a few azimuthal modes in the interaction, it is still not a fully 3-D FEL code. However, they show that these 2-D programs can still be used for an elliptical beam whose aspect ratio is within certain limits. The author presents numerical results of FEL performance for the circular beam, the elliptical beam, and finally for the beam in the realistic LEUTL lattice.« less

Comparing an optical parametric oscillator (OPO) as a viable alternative for mid-infrared tissue ablation with a free electron laser (FEL).

PubMed

Mackanos, Mark A; Simanovskii, Dmitrii M; Contag, Christopher H; Kozub, John A; Jansen, E Duco

2012-11-01

Beneficial medical laser ablation removes material efficiently with minimal collateral damage. A Mark-III free electron laser (FEL), at a wavelength of 6.45 μm has demonstrated minimal damage and high ablation yield in ocular and neural tissues. While this wavelength has shown promise for surgical applications, further advances are limited by the high overhead for FEL use. Alternative mid-infrared sources are needed for further development. We compared the FEL with a 5-μs pulse duration with a Q-switched ZGP-OPO with a 100-ns pulse duration at mid-infrared wavelengths. There were no differences in the ablation threshold of water and mouse dermis with these two sources in spite of the difference in their pulse structures. There was a significant difference in crater depth between the ZGP:OPO and the FEL. At 6.1 μm, the OPO craters are eight times the depth of the FEL craters. The OPO craters at 6.45 and 6.73 μm were six and five times the depth of the FEL craters, respectively. Bright-field (pump-probe) images showed the classic ablation mechanism from formation of a plume through collapse and recoil. The crater formation, ejection, and collapse phases occurred on a faster time-scale with the OPO than with the FEL. This research showed that a ZGP-OPO laser could be a viable alternative to FEL for clinical applications.

Integrating the FEL on an All-Electric Ship

DTIC Science & Technology

2007-06-01

6 4. Optical Cavity ( Oscillator Configuration...36 Figure 12. Optical energy in an oscillator FEL with an electron beam tilt. ......................37 Figure 13. Optical energy in an oscillator ...38 Figure 15. Optical energy in an oscillator FEL with a mirror tilt. ....................................39 Figure 16. Diagram of a

An Overview of the MaRIE X-FEL and Electron Radiography LINAC RF Systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bradley, Joseph Thomas III; Rees, Daniel Earl; Scheinker, Alexander

The purpose of the Matter-Radiation Interactions in Extremes (MaRIE) facility at Los Alamos National Laboratory is to investigate the performance limits of materials in extreme environments. The MaRIE facility will utilize a 12 GeV linac to drive an X-ray Free-Electron Laser (FEL). Most of the same linac will also be used to perform electron radiography. The main linac is driven by two shorter linacs; one short linac optimized for X-FEL pulses and one for electron radiography. The RF systems have historically been the one of the largest single component costs of a linac. We will describe the details of themore » different types of RF systems required by each part of the linacs. Starting with the High Power RF system, we will present our methodology for the choice of RF system peak power and pulselength with respect to klystron parameters, modulator parameters, performance requirements and relative costs. We will also present an overview of the Low Level RF systems that are proposed for MaRIE and briefly describe their use with some proposed control schemes.« less

Method for separating FEL output beams from long wavelength radiation

DOEpatents

Neil, George; Shinn, Michelle D.; Gubeli, Joseph

2016-04-26

A method for improving the output beam quality of a free electron laser (FEL) by reducing the amount of emission at wavelengths longer than the electron pulse length and reducing the amount of edge radiation. A mirror constructed of thermally conductive material and having an aperture therein is placed at an oblique angle with respect to the beam downstream of the bending magnet but before any sensitive use of the FEL beam. The aperture in the mirror is sized to deflect emission longer than the wavelength of the FEL output while having a minor impact on the FEL output beam. A properly sized aperture will enable the FEL radiation, which is coherent and generally at a much shorter wavelength than the bending radiations, to pass through the aperture mirror. The much higher divergence bending radiations will subsequently strike the aperture mirror and be reflected safely out of the way.

Regions of Stability of FEL Oscillators,

DTIC Science & Technology

1987-10-01

EGION5 OF STABILITY OF FEL OCCILLATORS(U) MARYLAND 1/1 UNIV COLLEGE PARK LAB FOR PLASMA AND FUSION ENERGY STUDIES B LEVUSH ET AL OCT 87 UNLPF-88...MARYLAND j LABRATRY ORPLASMA AND FUSION ENERGY . STUDIES...:’ COLLEGE PARK, MARYLANI) ’ 20742- a 0.6.3 ~0 DT!C IlELEcTEI REGIONS OF STABILITY OF FEL...University of Maryland, Laboratory for Plasma and Fusion Energy Studies ~IT~UTION ST TEMEN Approved iom public :elOOS61=D triution Unli __e REGIONS OF

Design considerations of 10 kW-scale extreme ultraviolet SASE FEL for lithography

NASA Astrophysics Data System (ADS)

Pagani, C.; Saldin, E. L.; Schneidmiller, E. A.; Yurkov, M. V.

2001-05-01

The semiconductor industry growth is driven to a large extent by steady advancements in microlithography. According to the newly updated industry roadmap, the 70 nm generation is anticipated to be available in the year 2008. However, the path to get there is not obvious. The problem of construction of Extreme Ultraviolet (EUV) quantum laser for lithography is still unsolved: progress in this field is rather moderate and we cannot expect a significant break through in the near future. Nevertheless, there is clear path for optical lithography to take us to sub- 100 nm dimensions. Theoretical and experimental work in free electron laser (FEL) and accelerator physics and technology over the last 10 years has pointed to the possibility of generation of high-power optical beams with laser-like characteristics in the EUV spectral range. Recently, there have been important advances in demonstrating a high-gain self-amplified spontaneous emission (SASE) FEL at 100 nm wavelength (Andruszkov et al., Phys. Rev. Lett. 85 (2000), 3825). In the SASE FEL powerful, coherent radiation is produced by the electron beam during single-pass of the undulator, thus there are no apparent limitations which would prevent operation at very short wavelength range and to increase the average output power of this device up to 10 kW level. The use of superconducting energy-recovery linac could produce a major, cost-effective facility with wall plug power to output optical power efficiency of about 1%. A 10-kW-scale transversely coherent radiation source with narrow bandwidth (0.5%) and variable wavelength could be an excellent tool for manufacturing computer chips with the minimum feature size below 100 nm. All components of the proposed SASE FEL equipment (injector, driver accelerator structure, energy-recovery system, undulator, etc.) have been demonstrated in practice. This is guaranteed success in the time schedule requirement.

Design considerations of 10 kW-scale, extreme ultraviolet SASE FEL for lithography

NASA Astrophysics Data System (ADS)

Pagani, C.; Saldin, E. L.; Schneidmiller, E. A.; Yurkov, M. V.

2001-12-01

The semiconductor industry growth is driven to a large extent by steady advancements in microlithography. According to the newly updated industry road map, the 70 nm generation is anticipated to be available in the year 2008. However, the path to get there is not clear. The problem of construction of extreme ultraviolet (EUV) quantum lasers for lithography is still unsolved: progress in this field is rather moderate and we cannot expect a significant breakthrough in the near future. Nevertheless, there is clear path for optical lithography to take us to sub-100 nm dimensions. Theoretical and experimental work in Self-Amplified Spontaneous Emission (SASE) Free Electron Lasers (FEL) physics and the physics of superconducting linear accelerators over the last 10 years has pointed to the possibility of the generation of high-power optical beams with laser-like characteristics in the EUV spectral range. Recently, there have been important advances in demonstrating a high-gain SASE FEL at 100 nm wavelength (J. Andruszkov, et al., Phys. Rev. Lett. 85 (2000) 3821). The SASE FEL concept eliminates the need for an optical cavity. As a result, there are no apparent limitations which would prevent operating at very short wavelength range and increasing the average output power of this device up to 10-kW level. The use of super conducting energy-recovery linac could produce a major, cost-efficient facility with wall plug power to output optical power efficiency of about 1%. A 10-kW scale transversely coherent radiation source with narrow bandwidth (0.5%) and variable wavelength could be excellent tool for manufacturing computer chips with the minimum feature size below 100 nm. All components of the proposed SASE FEL equipment (injector, driver accelerator structure, energy recovery system, undulator, etc.) have been demonstrated in practice. This is guaranteed success in the time-schedule requirement.

Perspective: Opportunities for ultrafast science at SwissFEL

PubMed Central

Abela, Rafael; Beaud, Paul; van Bokhoven, Jeroen A.; Chergui, Majed; Feurer, Thomas; Haase, Johannes; Ingold, Gerhard; Johnson, Steven L.; Knopp, Gregor; Lemke, Henrik; Milne, Chris J.; Pedrini, Bill; Radi, Peter; Schertler, Gebhard; Standfuss, Jörg; Staub, Urs; Patthey, Luc

2018-01-01

We present the main specifications of the newly constructed Swiss Free Electron Laser, SwissFEL, and explore its potential impact on ultrafast science. In light of recent achievements at current X-ray free electron lasers, we discuss the potential territory for new scientific breakthroughs offered by SwissFEL in Chemistry, Biology, and Materials Science, as well as nonlinear X-ray science. PMID:29376109

Phased Demolition of an Occupied Facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brede, Lawrence M.; Lauterbach, Merl J.; Witt, Brandon W.

2008-01-15

The U.S. government constructed the K-1401 facility in the late 1940's as a support building for various projects supporting the uranium gaseous diffusion process. In 2004 the U.S. Department of Energy authorized Bechtel Jacobs Company, LLC (BJC) to decontaminate and demolish the facility. The K-1401 facility was used for a variety of industrial purposes supporting the gaseous diffusion process. Many different substances were used to support these processes over the years and as a result different parts of the facility were contaminated with fluorine, chlorine trifluoride, uranium and technetium radiological contamination, asbestos, and mercury. The total facility area is 46,015more » m{sup 2} (495,000 sf) including a 6,800 m{sup 2} basement (73,200 sf). In addition to the contamination areas in the facility, a large portion was leased to businesses for re-industrialization when the D and D activities began. The work scope associated with the facility included purging and steam cleaning the former fluorine and chlorine trifluoride systems, decontaminating loose radiologically contaminated and mercury spill areas, dismantling former radiological lines contaminated with uranium oxide compounds and technetium, abating all asbestos containing material, and demolishing the facility. These various situations contributed to the challenge of successfully conducting D and D tasks on the facility. In order to efficiently utilize the work force, demolition equipment, and waste hauling trucks the normal approach of decontaminating the facility of the hazardous materials, and then conducting demolition in series required a project schedule of five years, which is not cost effective. The entire project was planned with continuous demolition as the goal end state. As a result, the first activities, Phase 1, required to prepare sections for demolition, including steam cleaning fluorine and chlorine trifluoride process lines in basement and facility asbestos abatement, were

Design Concept for a Compact ERL to Drive a VUV/Soft X-Ray FEL

DOE Office of Scientific and Technical Information (OSTI.GOV)

Christopher Tennant ,David Douglas

2011-03-01

We explore possible upgrades of the existing Jefferson Laboratory IR/UV FEL driver to higher electron beam energy and shorter wavelength through use of multipass recirculation to drive an amplifier FEL. The system would require beam energy at the wiggler of 600 MeV with 1 mA of average current. The system must generate a high brightness beam, configure it appropriately, and preserve beam quality through the acceleration cycle ? including multiple recirculations ? and appropriately manage the phase space during energy recovery. The paper will discuss preliminary design analysis of the longitudinal match, space charge effects in the linac, and recirculatormore » design issues, including the potential for the microbunching instability. A design concept for the low energy recirculator and an emittance preserving lattice solution will be presented.« less

Validity and reliability of the Fels physical activity questionnaire for children.

PubMed

Treuth, Margarita S; Hou, Ningqi; Young, Deborah R; Maynard, L Michele

2005-03-01

The aim was to evaluate the reliability and validity of the Fels physical activity questionnaire (PAQ) for children 7-19 yr of age. A cross-sectional study was conducted among 130 girls and 99 boys in elementary (N=70), middle (N=81), and high (N=78) schools in rural Maryland. Weight and height were measured on the initial school visit. All the children then wore an Actiwatch accelerometer for 6 d. The Fels PAQ for children was given on two separate occasions to evaluate reliability and was compared with accelerometry data to evaluate validity. The reliability of the Fels PAQ for the girls, boys, and the elementary, middle, and high school age groups range was r=0.48-0.76. For the elementary school children, the correlation coefficient examining validity between the Fels PAQ total score and Actiwatch (counts per minute) was 0.34 (P=0.004). The correlation coefficients were lower in middle school (r=0.11, P=0.31) and high school (r=0.21, P=0.006) adolescents. The sport index of the Fels PAQ for children had the highest validity in the high school participants (r=0.34, P=0.002). The Fels PAQ for children is moderately reliable for all age groups of children. Validity of the Fels PAQ for children is acceptable for elementary and high school students when the total activity score or the sport index is used. The sport index was similar to the total score for elementary students but was a better measure of physical activity among high school students.

40 CFR 1037.645 - In-use compliance with family emission limits (FELs).

Code of Federal Regulations, 2013 CFR

2013-07-01

... different FELs, we may apply a higher FEL within the family than was applied to the vehicle's configuration... of 200 g/ton-mile, 210 g/ton-mile, and 220 g/ton-mile, we may apply a 220 g/ton-mile in-use FEL to vehicles that were originally designated as part of the 200 g/ton-mile or 210 g/ton-mile sub-families. (2...

40 CFR 1037.645 - In-use compliance with family emission limits (FELs).

Code of Federal Regulations, 2012 CFR

2012-07-01

... different FELs, we may apply a higher FEL within the family than was applied to the vehicle's configuration... of 200 g/ton-mile, 210 g/ton-mile, and 220 g/ton-mile, we may apply a 220 g/ton-mile in-use FEL to vehicles that were originally designated as part of the 200 g/ton-mile or 210 g/ton-mile sub-families. (2...

40 CFR 1037.645 - In-use compliance with family emission limits (FELs).

Code of Federal Regulations, 2014 CFR

2014-07-01

... different FELs, we may apply a higher FEL within the family than was applied to the vehicle's configuration... of 200 g/ton-mile, 210 g/ton-mile, and 220 g/ton-mile, we may apply a 220 g/ton-mile in-use FEL to vehicles that were originally designated as part of the 200 g/ton-mile or 210 g/ton-mile sub-families. (2...

FEL Trajectory Analysis for the VISA Experiment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nuhn, Heinz-Dieter

1998-10-06

The Visual to Infrared SASE Amplifier (VISA) [1] FEL is designed to achieve saturation at radiation wavelengths between 800 and 600 nm with a 4-m pure permanent magnet undulator. The undulator comprises four 99-cm segments each of which has four FODO focusing cells superposed on the beam by means of permanent magnets in the gap alongside the beam. Each segment will also have two beam position monitors and two sets of x-y dipole correctors. The trajectory walk-off in each segment will be reduced to a value smaller than the rms beam radius by means of magnet sorting, precise fabrication, andmore » post-fabrication shimming and trim magnets. However, this leaves possible inter-segment alignment errors. A trajectory analysis code has been used in combination with the FRED3D [2] FEL code to simulate the effect of the shimming procedure and segment alignment errors on the electron beam trajectory and to determine the sensitivity of the FEL gain process to trajectory errors. The paper describes the technique used to establish tolerances for the segment alignment.« less

FEL for the polymer processing industries

NASA Astrophysics Data System (ADS)

Kelley, Michael J.

1997-05-01

Polymers are everywhere in modern life because of their unique combination of end-use functionalities, ease of processing, recycling potential and modest cost. The physical and economic scope of the infrastructure committed to present polymers makes the introduction of entirely new chemistry unlikely. Rather, the breadth of commercial offerings more likely to shrink in the face of the widening mandate for recycling, especially of packaging. Improved performance and new functionality must therefore come by routes such as surface modification. However they must come with little environmental impact and at painfully low cost. Processing with strongly absorbed light offers unique advantages. The journal and patent literatures disclose a number of examples of benefits that can be achieved, principally by use of excimer lasers or special UV lamps. Examples of commercialization are few, however, because of the unit cost and maximum scale of existing light sources. A FEL, however, offers unique advantages: tunability to the optimum wavelength, potential for scale up to high average power, and a path to attractively low unit cost of light. A business analysis of prospective applications defines the technical and economic requirements a FEL for polymer surface processing must meet. These are compared to FEL technology as it now stands and as it is envisioned.

Optimization Studies of the FERMI at ELETTRA FEL Design

DOE Office of Scientific and Technical Information (OSTI.GOV)

De Ninno, Giovanni; Fawley, William M.; Penn, Gregory E.

The FERMI at ELETTRA project at Sincotrone Trieste involves two FEL's, each based upon the principle of seeded harmonic generation and using the existing ELETTRA injection linac at 1.2 GeV beam energy. Scheduled to be completed in 2008, FEL-1 will operate in 40-100 nm wavelength range and will involve one stage of harmonic up-conversion. The second undulator line, FEL-2, will begin operation two years later in the 10-40 nm wavelength range and use two harmonic stages operating as a cascade. The FEL design assumes continuous wavelength tunability over the full wavelength range, and polarization tunability of the output radiation includingmore » vertical or horizontal linear as well as helical polarization. The design considers focusing properties and segmentation of realizable undulators and available input seed lasers. We review the studies that have led to our current design. We present results of simulations using GENESIS and GINGER simulation codes including studies of various shot-to-shot fluctuations and undulator errors. Findings for the expected output radiation in terms of the power, transverse and longitudinal coherence are reported.« less

Coherence and linewidth studies of a 4-nm high power FEL

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fawley, W.M.; Sessler, A.M.; Scharlemann, E.T.

Recently the SSRL/SLAC and its collaborators elsewhere have considered the merits of a 2 to 4-nm high power FEL utilizing the SLAC linac electron beam. The FEL would be a single pass amplifier excited by spontaneous emission rather than an oscillator, in order to eliminate the need for a soft X-ray resonant cavity. We have used GINGER, a multifrequency 2D FEL simulation code, to study the expected linewidth and coherence properties of the FEL, in both the exponential and saturated gain regimes. We present results concerning the effective shot noise input power and mode shape, the expected subpercent output linemore » widths, photon flux, and the field temporal and spatial correlation functions. We also discuss the effects of tapering the wiggler upon the output power and line width.« less

A Test of Superradiance in an FEL Experiment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boyce, R

We describe the design of an FEL Amplifier Test Experiment (FATE)1 to demonstrate the superradiant short bunch regime of a Free Electron Laser in the 1-3 {micro}m wavelength range starting from noise. The relevance to the LCLS X-ray FEL [1] proposal is discussed and numerical simulations are shown. It is numerically demonstrated for the first time with the 2-D code GINGER, that clean-up of noise in the superradiant regime occurs even at low power levels.

A scheme for a shot-to-shot, femtosecond-resolved pulse length and arrival time measurement of free electron laser x-ray pulses that overcomes the time jitter problem between the FEL and the laser

NASA Astrophysics Data System (ADS)

Juranić, P. N.; Stepanov, A.; Peier, P.; Hauri, C. P.; Ischebeck, R.; Schlott, V.; Radović, M.; Erny, C.; Ardana-Lamas, F.; Monoszlai, B.; Gorgisyan, I.; Patthey, L.; Abela, R.

2014-03-01

The recent entry of X-ray free electron lasers (FELs) to all fields of physics has created an enormous need, both from scientists and operators, for better characterization of the beam created by these facilities. Of particular interest is the measurement of the arrival time of the FEL pulse relative to a laser pump, for pump-probe experiments, and the measurement of the FEL pulse length. This article describes a scheme that corrects one of the major sources of uncertainty in these types of measurements, namely the jitter in the arrival time of the FEL relative to an experimental laser beam. The setup presented here uses a combination of THz streak cameras and a spectral encoding setup to reduce the effect of an FEL's jitter, leaving the pulse length as the only variable that can affect the accuracy of the pulse length and arrival time measurement. A discussion of underlying principles is also provided.

GINGER simulations of short-pulse effects in the LEUTL FEL

DOE Office of Scientific and Technical Information (OSTI.GOV)

Huang, Z.; Fawley, W.M.

While the long-pulse, coasting beam model is often used in analysis and simulation of self-amplified spontaneous emission (SASE) free-electron lasers (FELs), many current SASE demonstration experiments employ relatively short electron bunches whose pulse length is on the order of the radiation slippage length. In particular, the low-energy undulator test line (LEUTL) FEL at the Advanced Photon Source has recently lased and nominally saturated in both visible and near-ultraviolet wavelength regions with a sub-ps pulse length that is somewhat shorter than the total slippage length in the 22-m undulator system. In this paper we explore several characteristics of the short pulsemore » regime for SASE FELs with the multidimensional, time-dependent simulation code GINGER, concentrating on making a direct comparison with the experimental results from LEUTL. Items of interest include the radiation gain length, pulse energy, saturation position, and spectral bandwidth. We address the importance of short-pulse effects when scaling the LEUTL results to proposed x-ray FELs and also briefly discuss the possible importance of coherent spontaneous emission at startup.« less

Face expressive lifting (FEL): an original surgical concept combined with bipolar radiofrequency.

PubMed

Divaris, Marc; Blugerman, Guillermo; Paul, Malcolm D

2014-01-01

Aging can lead to changes in facial expressions, transforming the positive youth expression of happiness to negative expressions as sadness, tiredness, and disgust. Local skin distension is another consequence of aging, which can be difficult to treat with rejuvenation procedures. The "face expressive lifting" (FEL) is an original concept in facial rejuvenation surgery. On the one hand, FEL integrates established convergent surgical techniques aiming to correct the age-related negative facial expressions. On the other hand, FEL incorporates novel bipolar RF technology aiming to correct local skin distension. One hundred twenty-six patients underwent FEL procedure. Facial expression and local skin distension were assessed with 2 years follow-up. There was a correction of negative facial expression for 96 patients (76 %) and a tightening of local skin distension in 100 % of cases. FEL is an effective procedure taking into account and able to correct both age-related negative changes in facial expression and local skin distension using radiofrequency. Level of Evidence: Level IV, therapeutic study.

Statistical properties of the radiation from SASE FEL operating in the linear regime

NASA Astrophysics Data System (ADS)

Saldin, E. L.; Schneidmiller, E. A.; Yurkov, M. V.

1998-02-01

The paper presents comprehensive analysis of statistical properties of the radiation from self amplified spontaneous emission (SASE) free electron laser operating in linear mode. The investigation has been performed in a one-dimensional approximation, assuming the electron pulse length to be much larger than a coherence length of the radiation. The following statistical properties of the SASE FEL radiation have been studied: field correlations, distribution of the radiation energy after monochromator installed at the FEL amplifier exit and photoelectric counting statistics of SASE FEL radiation. It is shown that the radiation from SASE FEL operating in linear regime possesses all the features corresponding to completely chaotic polarized radiation.

Analysis Of FEL Optical Systems With Grazing Incidence Mirrors

NASA Astrophysics Data System (ADS)

Knapp, C. E.; Viswanathan, V. K.; Bender, S. C.; Appert, Q. D.; Lawrence, G.; Barnard, C.

1986-11-01

The use of grazing incidence optics in resonators alleviates the problem of damage to the optical elements and permits higher powers in cavities of reasonable dimensions for a free electron laser (FEL). The design and manufacture of a grazing incidence beam expander for the Los Alamos FEL mock up has been completed. In this paper, we describe the analysis of a bare cavity, grazing incidence optical beam expander for an FEL system. Since the existing geometrical and physical optics codes were inadequate for such an analysis, the GLAD code was modified to include global coordinates, exact conic representation, raytracing, and exact aberration features to determine the alignment sensitivities of laser resonators. A resonator cavity has been manufactured and experimentally setup in the Optical Evaluation Laboratory at Los Alamos. Calculated performance is compared with the laboratory measurements obtained so far.

Rational design of hypoallergens applied to the major cat allergen Fel d 1.

PubMed

Saarne, T; Kaiser, L; Grönlund, H; Rasool, O; Gafvelin, G; van Hage-Hamsten, M

2005-05-01

Allergen-specific immunotherapy is the only treatment for allergic disease providing long-lasting symptom relief. Currently, it is mainly based on the use of crude allergen extracts. The treatment may be improved by the use of genetically engineered allergens, hypoallergens, aiming at a more effective and safer therapy. The aim of this study was to provide a rational design of hypoallergen candidates for immunotherapy by using structural information and knowledge of B and T cell epitopes of an allergen. The three-dimensional structure of the major cat allergen Fel d 1 was systematically altered by duplication of selected T cell epitopes and disruption of disulphide bonds. Seven Fel d 1 derivatives were generated and screened for allergenic reactivity in comparison with recombinant Fel d 1 in competition-ELISA. The allergenicity was further evaluated in basophil activation experiments and T cell reactivity was assessed in a lymphoproliferation assay. Three out of seven Fel d 1 derivatives, with two duplicated T cell epitopes and one or two disulphide bonds disrupted, were carefully evaluated. The three derivatives displayed a strong reduction in allergenicity with 400-900 times lower IgE-binding capacity than recombinant Fel d 1. In addition, they induced a lower degree of basophil activation and similar or stronger T cell proliferation than recombinant Fel d 1. By a rational approach, we have constructed three Fel d 1 hypoallergens with reduced IgE-binding capacities and retained T cell reactivities. This strategy may be applied to any well-characterized allergen to improve immunotherapy for allergic patients.

Fast synchrotron and FEL beam monitors based on single-crystal diamond detectors and InGaAs/InAlAs quantum well devices

NASA Astrophysics Data System (ADS)

Antonelli, M.; Di Fraia, M.; Carrato, S.; Cautero, G.; Menk, R. H.; Jark, W. H.; Ganbold, T.; Biasiol, G.; Callegari, C.; Coreno, M.; De Sio, A.; Pace, E.

2013-12-01

Simultaneous photon-beam position and intensity monitoring is becoming of increasing importance for new-generation synchrotron radiation sources and free-electron lasers (FEL). Thus, novel concepts of beam diagnostics are required in order to keep such beams under control. From this perspective diamond is a promising material for the production of semitransparent in situ photon beam monitors, which can withstand the high dose rates occurring in such radiation facilities. Here, we report on the development of freestanding, single-crystal chemical-vapor-deposited diamond detectors with segmented electrodes. Due to their direct, low-energy band gap, InGaAs quantum well devices operated at room temperature may also be used as fast detectors for photons ranging from visible to X-ray. These features are valuable in low-energy and time-resolved FEL applications. In particular, a novel segmented InGaAs/InAlAs device has been developed and will be discussed. Dedicated measurements carried out on both these devices at the Elettra Synchrotron show their capability to monitor the position and the intensity of the photon beam with bunch-by-bunch temporal performances. Furthermore, preliminary tests have been performed on diamond detectors at the Fermi FEL, extracting quantitative intensity and position information for 100-fs-wide FEL pulses with a photon energy of 28.8 eV.

Beam Conditioning for FELs: Consequences and Methods

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wolski, Andrzej; Penn, Gregory; Sessler, Andrew

2003-10-09

The consequences of beam conditioning in four example cases (VISA, a Soft X-Ray FEL, LCLS and a ''Greenfield'' FEL) are examined. It is shown that in emittance limited cases, proper conditioning reduces sensitivity to the transverse emittance, and allows stronger focusing in the undulator. Simulations show higher saturation power, with gain lengths reduced up to a factor of two. The beam dynamics in a general conditioning system are studied, with ''matching conditions'' derived for achieving conditioning without growth in effective emittance. Various conditioners are considered, and expressions derived for the amount of conditioning provided in each case when the matchingmore » conditions are satisfied. We discuss the prospects for conditioners based on laser and plasma systems.« less

Ultraviolet Free Electron Laser Facility preliminary design report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ben-Zvi, I.

1993-02-01

This document, the Preliminary Design Report (PDR) for the Brookhaven Ultraviolet Free Electron Laser (UV FEL) facility, describes all the elements of a facility proposed to meet the needs of a research community which requires ultraviolet sources not currently available as laboratory based lasers. Further, for these experiments, the requisite properties are not extant in either the existing second or upcoming third generation synchrotron light sources. This document is the result of our effort at BNL to identify potential users, determine the requirements of their experiments, and to design a facility which can not only satisfy the existing need, butmore » have adequate flexibility for possible future extensions as need dictates and as evolving technology allows. The PDR is comprised of three volumes. In this, the first volume, background for the development of the proposal is given, including descriptions of the UV FEL facility, and representative examples of the science it was designed to perform. Discussion of the limitations and potential directions for growth are also included. A detailed description of the facility design is then provided, which addresses the accelerator, optical, and experimental systems. Information regarding the conventional construction for the facility is contained in an addendum to volume one (IA).« less

Embryonic expression of festina lente (fel), a novel maternal gene, in the oligochaete annelid Tubifex tubifex.

PubMed

Nakamura, Takuma; Shiomi, Inori; Shimizu, Takashi

2017-11-01

We have cloned and characterized the expression of a novel maternal gene festina lente (designated Ttu-fel) from the clitellate annelid Tubifex tubifex. Northern blot analyses have shown that Ttu-fel mRNA is approximately 8 kbp in length and that its expression is restricted to oocytes undergoing maturation division and early embryos up to 22-cell stage. Maternal transcripts of Ttu-fel are first detected in oocytes in the ovary of young adults (ca. 40 days after hatching); its expression continues in growing oocytes in the ovisac. Ttu-fel mRNA is distributed broadly throughout the egg undergoing maturation divisions. During the process of ooplasmic segregation that results in the pole plasm formation, Ttu-fel mRNA becomes concentrated to the animal and vegetal poles. The RNA in the animal hemisphere is distributed in a gradient with highest concentration in the cortical region. During the first two cleavages, Ttu-fel mRNA is segregated to CD cell then to D cell; it is subsequently inherited by the three D quadtrant micromeres, 1d, 2d and 3d. Around the time of transition to 22-cell stage, Ttu-fel mRNA becomes undetectable throughout the embryo. Copyright © 2017 Elsevier B.V. All rights reserved.

The GALAXIE all-optical FEL project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rosenzweig, J. B.; Arab, E.; Andonian, G.

2012-12-21

We describe a comprehensive project, funded under the DARPA AXiS program, to develop an all-optical table-top X-ray FEL based on dielectric acceleration and electromagnetic undulators, yielding a compact source of coherent X-rays for medical and related applications. The compactness of this source demands that high field (>GV/m) acceleration and undulation-inducing fields be employed, thus giving rise to the project's acronym: GV/m AcceLerator And X-ray Integrated Experiment (GALAXIE). There are numerous physics and technical hurdles to surmount in this ambitious scenario, and the integrated solutions include: a biharmonic photonic TW structure, 200 micron wavelength electromagnetic undulators, 5 {mu}m laser development, ultra-highmore » brightness magnetized/asymmetric emittance electron beam generation, and SASE FEL operation. We describe the overall design philosophy of the project, the innovative approaches to addressing the challenges presented by the design, and the significant progress towards realization of these approaches in the nine months since project initialization.« less

The GALAXIE all-optical FEL project

NASA Astrophysics Data System (ADS)

Rosenzweig, J. B.; Arab, E.; Andonian, G.; Cahill, A.; Fitzmorris, K.; Fukusawa, A.; Hoang, P.; Jovanovic, I.; Marcus, G.; Marinelli, A.; Murokh, A.; Musumeci, P.; Naranjo, B.; O'Shea, B.; O'Shea, F.; Ovodenko, A.; Pogorelsky, I.; Putterman, S.; Roberts, K.; Shumail, M.; Tantawi, S.; Valloni, A.; Yakimenko, V.; Xu, G.

2012-12-01

We describe a comprehensive project, funded under the DARPA AXiS program, to develop an all-optical table-top X-ray FEL based on dielectric acceleration and electromagnetic undulators, yielding a compact source of coherent X-rays for medical and related applications. The compactness of this source demands that high field (>GV/m) acceleration and undulation-inducing fields be employed, thus giving rise to the project's acronym: GV/m AcceLerator And X-ray Integrated Experiment (GALAXIE). There are numerous physics and technical hurdles to surmount in this ambitious scenario, and the integrated solutions include: a biharmonic photonic TW structure, 200 micron wavelength electromagnetic undulators, 5 μm laser development, ultra-high brighness magnetized/asymmetric emittance electron beam generation, and SASE FEL operation. We describe the overall design philosophy of the project, the innovative approaches to addressing the challenges presented by the design, and the significant progress towards realization of these approaches in the nine months since project initialization.

40 CFR 1036.625 - In-use compliance with family emission limits (FELs).

Code of Federal Regulations, 2014 CFR

2014-07-01

... (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM NEW AND IN-USE HEAVY-DUTY HIGHWAY ENGINES... us to apply a higher in-use FEL for certain in-use engines, subject to the provisions of this section... higher in-use FELs to your engines, we would intend to accurately reflect the actual in-use performance...

40 CFR 1036.625 - In-use compliance with family emission limits (FELs).

Code of Federal Regulations, 2012 CFR

2012-07-01

... (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM NEW AND IN-USE HEAVY-DUTY HIGHWAY ENGINES... us to apply a higher in-use FEL for certain in-use engines, subject to the provisions of this section... higher in-use FELs to your engines, we would intend to accurately reflect the actual in-use performance...

40 CFR 1036.625 - In-use compliance with family emission limits (FELs).

Code of Federal Regulations, 2013 CFR

2013-07-01

... (CONTINUED) AIR POLLUTION CONTROLS CONTROL OF EMISSIONS FROM NEW AND IN-USE HEAVY-DUTY HIGHWAY ENGINES... us to apply a higher in-use FEL for certain in-use engines, subject to the provisions of this section... higher in-use FELs to your engines, we would intend to accurately reflect the actual in-use performance...

Selenium single-wavelength anomalous diffraction de novo phasing using an X-ray-free electron laser

DOE PAGES

Hunter, Mark S.; Yoon, Chun Hong; DeMirci, Hasan; ...

2016-11-04

Structural information about biological macromolecules near the atomic scale provides important insight into the functions of these molecules. To date, X-ray crystallography has been the predominant method used for macromolecular structure determination. However, challenges exist when solving structures with X-rays, including the phase problem and radiation damage. X-ray-free electron lasers (X-ray FELs) have enabled collection of diffraction information before the onset of radiation damage, yet the majority of structures solved at X-ray FELs have been phased using external information via molecular replacement. De novo phasing at X-ray FELs has proven challenging due in part to per-pulse variations in intensity andmore » wavelength. Here we report the solution of a selenobiotinyl-streptavidin structure using phases obtained by the anomalous diffraction of selenium measured at a single wavelength (Se-SAD) at the Linac Coherent Light Source. Finally, our results demonstrate Se-SAD, routinely employed at synchrotrons for novel structure determination, is now possible at X-ray FELs.« less

Lightning control system using high power microwave FEL

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shiho, M.; Watanbe, A.; Kawasaki, S.

A research project for developing a thunder lightning control system using an induction linac based high power microwave free electron laser (FEL) started at JAERI The system will produce weakly ionized plasma rod in the atmosphere by high power microwaves and control a lightning path, away from , e. g., nuclear power stations and rocket launchers. It has been known that about MW/cm{sup 2} power density is enough for the atmospheric breakdown in the microwave region, and which means high power microwave FEL with GW level output power is feasible for atmospheric breakdown, and accordingly is feasible for thunder lightningmore » control tool with making a conductive plasma channel in the atmosphere. From the microwave attenuation consideration in the atmosphere, FEL of 35GHz(0.13dB/km), 90GHz(0.35dB/km), 140GHz(1.7dB/km), and of 270 GHz(4.5dB/km) are the best candidates for the system. Comparing with other proposed lightning control system using visible or ultraviolet laser, the system using microwave has an advantage that microwave suffers smaller attenuation by rain or snow which always exist in the real atmospheric circumstances when lightning occurs.« less

The cat lipocalin Fel d 7 and its cross-reactivity with the dog lipocalin Can f 1.

PubMed

Apostolovic, D; Sánchez-Vidaurre, S; Waden, K; Curin, M; Grundström, J; Gafvelin, G; Cirkovic Velickovic, T; Grönlund, H; Thomas, W R; Valenta, R; Hamsten, C; van Hage, M

2016-10-01

We investigated the prevalence of sensitization to the cat lipocalin Fel d 7 among 140 cat-sensitized Swedish patients and elucidated its allergenic activity and cross-reactivity with the dog lipocalin Can f 1. Sixty-five of 140 patients had IgE to rFel d 7 whereof 60 also had IgE to rCan f 1. A moderate correlation between IgE levels to rFel d 7 and rCan f 1 was found. rFel d 7 activated basophils in vitro and inhibited IgE binding to rCan f 1 in 4 of 13 patients, whereas rCan f 1 inhibited IgE binding to rFel d 7 in 7 of 13 patients. Fel d 7 and Can f 1 showed high similarities in protein structure and epitopes in common were found using cross-reactive antisera. Fel d 7 is a common allergen in a Swedish cat-sensitized population that cross-reacts with Can f 1, and may contribute to symptoms in cat- but also in dog-allergic patients. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Field Encapsulation Library The FEL 2.2 User Guide

NASA Technical Reports Server (NTRS)

Moran, Patrick J.; Henze, Chris; Ellsworth, David

1999-01-01

This document describes version 2.2 of the Field Encapsulation Library (FEL), a library of mesh and field classes. FEL is a library for programmers - it is a "building block" enabling the rapid development of applications by a user. Since FEL is a library intended for code development, it is essential that enough technical detail be provided so that one can make full use of the code. Providing such detail requires some assumptions with respect to the reader's familiarity with the library implementation language, C++, particularly C++ with templates. We have done our best to make the explanations accessible to those who may not be completely C++ literate. Nevertheless, familiarity with the language will certainly help one's understanding of how and why things work the way they do. One consolation is that the level of understanding essential for using the library is significantly less than the level that one should have in order to modify or extend the library. One more remark on C++ templates: Templates have been a source of both joy and frustration for us. The frustration stems from the lack of mature or complete implementations that one has to work with. Template problems rear their ugly head particularly when porting. When porting C code, successfully compiling to a set of object files typically means that one is almost done. With templated C++ and the current state of the compilers and linkers, generating the object files is often only the beginning of the fun. On the other hand, templates are quite powerful. Used judiciously, templates enable more succinct designs and more efficient code. Templates also help with code maintenance. Designers can avoid creating objects that are the same in many respects, but not exactly the same. For example, FEL fields are templated by node type, thus the code for scalar fields and vector fields is shared. Furthermore, node type templating allows the library user to instantiate fields with data types not provided by the FEL

Reflection Matrix for Optical Resonators in FEL (Free Electron Lasers) Oscillators

DTIC Science & Technology

1988-09-22

is the dominant factor determining the reflction coefficient. The effects of deflecting tho’ light beam enter as small corrections, of first order in...RESONATORS IN FEL OSCILLATORS I. INTRODUCTION 1-7 Free Electron Lasers (FEL) operating as oscillators require the 8-10 trapping of light pulses between...The simplest oscillator configuration is that of an open resonator with two opposed identical mirrors. The radiation vector potential for this

Laser-induced fine structures on silicon exposed to THz-FEL

NASA Astrophysics Data System (ADS)

Irizawa, Akinori; Suga, Shigemasa; Nagashima, Takeshi; Higashiya, Atsushi; Hashida, Masaki; Sakabe, Shuji

2017-12-01

We found the irradiation of focused linearly polarized terahertz (THz)-waves emitted from THz free-electron laser (THz-FEL) engraved fine periodic stripe structures on the surfaces of single-crystal Si wafers. The experiments were performed at several wavelengths ranging from 50 to 82 μm with a macro-pulse fluence up to 32 J/cm2. The engraved structures are considered equivalent to the laser-induced periodic surface structures (LIPSS) produced by the irradiation of a femtosecond (fs)-pulsed laser in the near-infrared (NIR) region. However, the minimum period of ˜1/25 of the wavelength in the present case of THz-FEL is surely much smaller than those reported so far by use of fs-lasers and no more explicable by the so far proposed mechanisms. The finer LIPSS confirmed by longer-wavelength laser excitation by means of THz-FEL motivates investigation into the universal mechanism of LIPSS formation, which has been under a hot debate for decades.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yavas, Oe.

The Turkish Accelerator Center (TAC) Project was started in 1997 with support of the State Planning Organization (SPO) of Turkey under Ankara University's coordination. After completing Feasibility Report (FR, 2000) and Conceptual Design Repot (CDR, 2005), third phase of the project was started in 2006 as an inter-university project with support of SPO. Third phase of the project has two main scientific goals: to write Technical Design Report (TDR) of TAC and to establish an Infrared Free Electron Laser (IR FEL) facility as a first step. The first facility and TDR studies are planned to be completed in 2012. Constructionmore » phase of TAC will cover 2013-2023. TAC collaboration include ten Turkish Universities: Ankara, Gazi, Istanbul, Bogazici, Dogus, Uludag, Dumlupmar, Nigde, Erciyes and S. Demirel Universities. It was planned that the first facility will be an IR FEL and Bremsstrahlung laboratory based on 15-40 MeV electron linac and two optical cavities with 2.5 and 9 cm undulators to scan 2-250 microns wavelength range. Main purpose of the facility is to use IR FEL for research in material science, nonlinear optics, semiconductors, biotechnology, medicine and photochemical processes. In this study; aims, regional importance, main parts and main parameters of TAC and TAC IR FEL and Bremsstrahlung facility are explained. Road map of the TAC project is given. National and international collaborations are explained.« less

Beam conditioning for FELs: Consequences and methods

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wolski, A.; Penn, G.; Sessler, A.

2004-06-29

The consequences of beam conditioning in four example cases (VISA, a Soft X-Ray FEL, LCLS and a ''Greenfield'' FEL) are examined. It is shown that in emittance limited cases, proper conditioning reduces sensitivity to the transverse emittance and, furthermore, allows for stronger focusing in the undulator. Simulations show higher saturation power, with gain lengths reduced by a factor of two or more. The beam dynamics in a general conditioning system are studied, with ''matching conditions'' derived for achieving conditioning without growth in the effective emittance. Various conditioning lattices are considered, and expressions derived for the amount of conditioning provided inmore » each case when the matching conditions are satisfied. These results show that there is no fundamental obstacle to producing beam conditioning, and that the problem can be reduced to one of proper lattice design. Nevertheless, beam conditioning will not be easy to implement in practice.« less

Genetic evolution of bacteriophage. I. Hybrids between unrelated bacteriophages P22 and Fels 2.

PubMed

Yamamoto, N

1969-01-01

A new bacteriophage species, designated F22, was isolated from phage P22 stocks grown on Salmonella typhimurium Q1 lysogenic for Fels 2 at a frequency of less than 10(-11). P22 has a very short tail with a hexagonal base plate and six spikes. Phage Fels 2 is morphologically similar to E. coli T-even phages, having a long tail with a contractile sheath and carrying no genetic region related to P22. Phage F22 is morphologically and serologically indistinguishable from Fels 2, but carries the c(c(1), c(2), and c(3)) markers of P22. The color markers h(21), g, and m(3) of P22 do not appear in F22. Thus, F22 is evidently a recombinant between the unrelated bacteriophages P22 and Fels 2. The recombination between unrelated bacteriophages could play an important role in the evolution of bacteriophages.

Commissioning for the European XFEL facility

NASA Astrophysics Data System (ADS)

Nölle, D.

2017-06-01

The European XFEL is a 4th generation light source based on the Self Amplified Spontaneous Emission (SASE) FreeElectron-Laser concept. It is currently being commissioned in North- Germany. The core installation is a 17.5 GeV superconducting accelerator driving 3 SASE lines with photon energies from 1 to beyond 20 keV range with a maximum of 27.000 pulses per second. The international facility is organized as a limited liability company with shareholders from the contributing countries. DESY has taken over the leadership of the accelerator construction consortium, and will be in charge of the operation of the accelerator complex. The facility was set up with contributions from the 11 shareholder countries, either being hardware systems and/or staff or cash contributions. The construction is almost complete, and the commissioning phase has started by the end of 2015. This contribution will report the status of the accelerator complex with emphasis on the commissioning of the accelerator and an outlook to the commissioning of the SASE 1 FEL line.

PFM2: a 32 × 32 processor for X-ray diffraction imaging at FELs

NASA Astrophysics Data System (ADS)

Manghisoni, M.; Fabris, L.; Re, V.; Traversi, G.; Ratti, L.; Grassi, M.; Lodola, L.; Malcovati, P.; Vacchi, C.; Pancheri, L.; Benkechcache, M. E. A.; Dalla Betta, G.-F.; Xu, H.; Verzellesi, G.; Ronchin, S.; Boscardin, M.; Batignani, G.; Bettarini, S.; Casarosa, G.; Forti, F.; Giorgi, M.; Paladino, A.; Paoloni, E.; Rizzo, G.; Morsani, F.

2016-11-01

This work is concerned with the design of a readout chip for application to experiments at the next generation X-ray Free Electron Lasers (FEL). The ASIC, named PixFEL Matrix (PFM2), has been designed in a 65 nm CMOS technology and consists of 32 × 32 pixels. Each cell covers an area of 110 × 110 μm2 and includes a low-noise charge sensitive amplifier (CSA) with dynamic signal compression, a time-variant shaper used to process the preamplifier output signal, a 10-bit successive approximation register (SAR) analog-to-digital converter (ADC) and digital circuitry for channel control and data readout. Two different solutions for the readout channel, based on different versions of the time-variant filter, have been integrated in the chip. Both solutions can be operated in such a way to cope with the high frame rate (exceeding 1 MHz) foreseen for future X-ray FEL machines. The ASIC will be bump bonded to a slim/active edge pixel sensor to form the first demonstrator for the PixFEL X-ray imager. This work has been carried out in the frame of the PixFEL project funded by Istituto Nazionale di Fisica Nucleare (INFN), Italy.

Experimental Characterization of Nonlinear Harmonic Radiation from a Visible SASE FEL at Saturation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cornacchia, Massimo

2002-08-19

Nonlinear harmonic radiation was observed using the VISA SASE FEL at saturation. The gain lengths, spectra and energies of the three lowest SASE FEL modes were experimentally characterized. Both the measured harmonic gain lengths and center spectral wavelengths are shown to decrease with harmonic number, n, which is consistent with nonlinear harmonic theory. The measured energies for both second and third harmonics are about 1% of the fundamental; the strong second harmonic radiation ({approx} 1 {micro}J) observed is unique for low energy SASE FELs. These experimental results demonstrate for the first time the feasibility of using nonlinear harmonic SASE FELmore » radiation to produce coherent, femtosecond X-rays.« less

Acute optic nerve sheath fenestration in humans using the free electron laser (FEL): a case report

NASA Astrophysics Data System (ADS)

Joos, Karen M.; Mawn, Louise A.; Shen, Jin-Hui; Jansen, E. Duco; Casagrande, Vivien A.

2002-06-01

Our previous studies using rabbits and monkeys showed that the Amide II wavelength (6.45 micrometers ) produced by the FEL could efficiently produce an optic nerve sheath fenestration with minimal damage. In order to determine if the technology safely could be applied to human surgery, we used 2 blind human eyes during enucleation to compare the results of producing fenestrations with the FEL or a scissors. FDA and Vanderbilt IRB approvals, and individual patient consents were obtained. The FEL energy was transmitted to a human operating room. After disinsertion of the medial rectus muscle, an optic nerve sheath fenestration (2 mm diameter) was made with either the FEL (6.45 micrometers , 325 micrometers spot size, 30 Hz, 3 mJ) through a hollow waveguide surgical probe or with a scissors. The enucleation was then completed. The optic nerve was dissected from the globe and fixed. Specimens were examined histologically. Dural incisions were effective with both methods. FEL energy at 6.45 micrometers can be transmitted to an operating room and delivered to human ocular tissue through a hollow waveguide surgical probe. This FEL wavelength can produce an optic nerve sheath fenestration without acute direct damage to the nerve in this case report.

Effect of normalized plasma frequency on electron phase-space orbits in a free-electron laser

NASA Astrophysics Data System (ADS)

Ji, Yu-Pin; Wang, Shi-Jian; Xu, Jing-Yue; Xu, Yong-Gen; Liu, Xiao-Xu; Lu, Hong; Huang, Xiao-Li; Zhang, Shi-Chang

2014-02-01

Irregular phase-space orbits of the electrons are harmful to the electron-beam transport quality and hence deteriorate the performance of a free-electron laser (FEL). In previous literature, it was demonstrated that the irregularity of the electron phase-space orbits could be caused in several ways, such as varying the wiggler amplitude and inducing sidebands. Based on a Hamiltonian model with a set of self-consistent differential equations, it is shown in this paper that the electron-beam normalized plasma frequency functions not only couple the electron motion with the FEL wave, which results in the evolution of the FEL wave field and a possible power saturation at a large beam current, but also cause the irregularity of the electron phase-space orbits when the normalized plasma frequency has a sufficiently large value, even if the initial energy of the electron is equal to the synchronous energy or the FEL wave does not reach power saturation.

77 FR 75660 - Agency Information Collection Activities; Proposed Collection; Comments Requested: FEL Out-of...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-21

...] Agency Information Collection Activities; Proposed Collection; Comments Requested: FEL Out-of-Business.... (2) Title of the Form/Collection: FEL Out of Business Records. (3) Form Number: None. Bureau of..., as well as a brief abstract: Primary: Business or other for-profit. Other: None. Need for Collection...

GENETIC EVOLUTION OF BACTERIOPHAGE, I. HYBRIDS BETWEEN UNRELATED BACTERIOPHAGES P22 AND FELS 2*

PubMed Central

Yamamoto, Nobuto

1969-01-01

A new bacteriophage species, designated F22, was isolated from phage P22 stocks grown on Salmonella typhimurium Q1 lysogenic for Fels 2 at a frequency of less than 10-11. P22 has a very short tail with a hexagonal base plate and six spikes. Phage Fels 2 is morphologically similar to E. coli T-even phages, having a long tail with a contractile sheath and carrying no genetic region related to P22. Phage F22 is morphologically and serologically indistinguishable from Fels 2, but carries the c(c1, c2, and c3) markers of P22. The color markers h21, g, and m3 of P22 do not appear in F22. Thus, F22 is evidently a recombinant between the unrelated bacteriophages P22 and Fels 2. The recombination between unrelated bacteriophages could play an important role in the evolution of bacteriophages. Images PMID:4890254

Burst mode FEL with the ETA-III induction linac

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lasnier, C.J.; Allen, S.L.; Felker, B.

1993-05-13

Pulses of 140 GHz microwaves have been produced at a 2 kHz rate using the ETA-III induction linac and IMP wiggler. The accelerator was run in bursts of up to 50 pulses at 6 MeV and greater than 2 kA peak current. A feedback timing control system was used to synchronize acceleration voltage pulses with the electron beam, resulting in sufficient reduction of the corkscrew and energy sweep for efficient FEL operation. Peak microwave power for short bursts was in the range 0.5--1.1 GW, which is comparable to the single-pulse peak power of 0.75--2 GW. FEL bursts of more thanmore » 25 pulses were obtained.« less

Using The SLAC Two-Mile Accelerator for Powering an FEL

DOE Office of Scientific and Technical Information (OSTI.GOV)

Barletta, W.A.; /LLNL, Livermore; Sessler, A.M.

2012-06-29

A parameter survey is made, employing the recently developed 2D formalism for an FEL, of the characteristics of an FEL using the SLAC accelerator. Attention is focused upon a wavelength of 40 {angstrom} (the water window) and 1 {angstrom} case is also presented. They consider employing the SLAC linac with its present operating parameters and with improved parameters such as would be supplied by a new photo-cathode injector. They find that improved parameters are necessary, but that the parameters presently achieved with present-day photo-cathode guns are adequate to reach the water window.

The role of radiation reaction in Lienard-Wiechert description of FEL interaction

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kimel, I.; Elias, L.R.

1995-12-31

The most common theoretical analysis of the FEL interaction is based on the set of equations consisting of Lorentz and wave equations. This approach explains most of FEL features and, in particular, works well to describe operation in the amplifier mode. In that approach however, there are some difficulties in describing operation in oscillator mode, as well as self amplified spontaneous emission. In particular, it is not possible to describe the start up stage since there is no wave to start with. It is clear that a different approach is required in such situations. That is why we have pursuedmore » the study of the FEL interaction in the framework of Lorentz plus Lienard-Wiechert equations. The Lienard-Wiechert Lorentz equation approach however, presents its own set of problems. Variation in energy of the electrons is given exclusively by the Lorentz equation. Thus, the energy lost due to the radiation process is not properly taken into account. This, of course, is a long standing problem in classical electrodynamics. In order to restore energy conservation radiation reaction has to be incorporated into the framework. The first question in that regard has to do with which form of the radiation reaction equations is the most convenient for computations in the FEL process. This has to do with the fact that historically, radiation reaction has been added in an ad hoc manner instead of being derived from the fundamental equations. Another problem discussed is how to take into account the radiation reaction in a collective manner in the interaction among electrons. Also discussed is the radiation reaction vis a vi the coherence properties of the FEL process.« less

A 20fs synchronization system for lasers and cavities in accelerators and FELs

NASA Astrophysics Data System (ADS)

Wilcox, R. B.; Byrd, J. M.; Doolittle, L. R.; Huang, G.; Staples, J. W.

2010-02-01

A fiber-optic RF distribution system has been developed for synchronizing lasers and RF plants in short pulse FELs. Typical requirements are 50-100fs rms over time periods from 1ms to several hours. Our system amplitude modulates a CW laser signal, senses fiber length using an interferometer, and feed-forward corrects the RF phase digitally at the receiver. We demonstrate less than 15fs rms error over 12 hours, between two independent channels with a fiber path length difference of 200m and transmitting S-band RF. The system is constructed using standard telecommunications components, and uses regular telecom fiber.

Simulation studies of a XUV/soft X-ray harmonic-cascade FEL for the proposed LBNL recirculating linac*

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fawley, W.M.; Barletta, W.A.; Corlett, J.N.

Presently there is significant interest at LBNL in designing and building a facility for ultrafast (i.e. femtosecond time scale) x-ray science based upon a superconducting, recirculating RF linac (see Corlett et al. for more details). In addition to producing synchrotron radiation pulses in the 1-15 keV energy range, we are also considering adding one or more free-electron laser (FEL) beamlines using a harmonic cascade approach to produce coherent XUV soft X-ray emission beginning with a strong input seed at {approx}200 nm wavelength obtained from a ''conventional'' laser. Each cascade is composed of a radiator together with a modulator section, separatedmore » by a magnetic chicane. The chicane temporally delays the electron beam pulse in order that a ''virgin'' pulse region (with undegraded energy spread) be brought into synchronism with the radiation pulse, which together then undergo FEL action in the modulator. We present various results obtained with the GINGER simulation code examining final output sensitivity to initial electron beam parameters. We also discuss the effects of spontaneous emission and shot noise upon this particular cascade approach which can limit the final output coherence.« less

The ETA-II induction linac as a high-average-power FEL driver

NASA Astrophysics Data System (ADS)

Nexsen, W. E.; Atkinson, D. P.; Barrett, D. M.; Chen, Y.-J.; Clark, J. C.; Griffith, L. V.; Kirbie, H. C.; Newton, M. A.; Paul, A. C.; Sampayan, S.; Throop, A. L.; Turner, W. C.

1990-10-01

The Experimental Test Accelerator II (ETA-II) is the first induction linac designed specifically to FEL requirements. It is primarily intended to demonstrate induction accelerator technology for high-average-power, high-brightness electron beams, and will be used to drive a 140 and 250 GHz microwave FEL for plasma heating experiments in the Microwave Tokamak Experiment (MTX) at LLNL. Its features include high-vacuum design which allows the use of an intrinsically bright dispenser cathode, induction cells designed to minimize BBU growth rate, and careful attention to magnetic alignment to minimize radial sweep due to beam corkscrew. The use of magnetic switches allows high-average-power operation. At present ETA-II is being used to drive 140 GHz plasma heating experiments. These experiments require nominal beam parameters of 6 MeV energy, 2 kA current, 20 ns pulse width and a brightness of 1 × 108 A/(m rad)2 at the wiggler with a pulse repetition frequency (prf) of 0.5 Hz. Future 250 GHz experiments require beam parameters of 10 MeV energy, 3 kA current, 50 ns pulse width and a brightness of 1 × 108 A/(m rad)2 with a 5 kHz prf for 0.5 s. In this paper we discuss the present status of ETA-II parameters and the phased development program necessary to satisfy these future requirements.

Immunological differences in the global release of the major cat allergen Fel d 1 are influenced by sex and behaviour.

PubMed

Bienboire-Frosini, Cécile; Cozzi, Alessandro; Lafont-Lecuelle, Céline; Vervloet, Daniel; Ronin, Catherine; Pageat, Patrick

2012-07-01

The biological function of Fel d 1, the major cat allergen released in the environment, is still unclear despite studies suggesting a putative role in chemical communication. Structural and immunological polymorphisms of Fel d 1 have been described. This study examined how Fel d 1 immunological polymorphism may have a physiological origin by estimating a potential relationship with the sex of cats and cat-human interactions. Samples from bath washes of 21 cats were screened to study antibody binding to Fel d 1 using an ELISA. Personality and Tolerance Handling scores were used to assess the behaviour of the cats. In the washes, Fel d 1 concentrations were significantly lower in females than in males (P<0.05). Slopes from the ELISA dose-dependent curves varied among the cats: males secreted Fel d 1 variants with higher antibody recognition than females (P<0.01). Females that were aggressive and difficult to handle displayed a diminished slope value, and therefore a weaker Fel d 1 immunoreactivity in global washes, compared to females that were sociable (P=0.09) and easy to handle (P=0.07). This study shows a variable immunological polymorphism of Fel d 1 within a cat population, particularly between males and females, and this polymorphism appears to be related to cat-human interactions. Copyright © 2011 Elsevier Ltd. All rights reserved.

SYNCHROTRON RADIATION, FREE ELECTRON LASER, APPLICATION OF NUCLEAR TECHNOLOGY, ETC.: Operating the SDUV-FEL with the echo-enabled harmonic generation scheme

NASA Astrophysics Data System (ADS)

Chen, Jian-Hui; Deng, Hai-Xiao; Gu, Qiang; Li, Dong-Guo; Wang, Dong; Zhang, Meng; Zhao, Zhen-Tang

2009-08-01

Using the recently proposed echo-enabled harmonic generation (EEHG) free-electron laser (FEL) scheme, it is shown that operating the Shanghai deep ultraviolet FEL (SDUV-FEL) with single-stage to higher harmonics is very promising, with higher frequency up-conversion efficiency, higher harmonic selectivity and lower power requirement of the seed laser. The considerations on a proof-of-principle experiment and expected performance in SDUV-FEL are given.

FELS FOUNDATION PROJECT FOR DEVELOPING YOUTH POTENTIAL.

ERIC Educational Resources Information Center

BAIR, ROBERT A.; AND OTHERS

THE OPERATION OF THE FELS FOUNDATION PROJECT FOR DEVELOPING YOUTH POTENTIAL IN HANFORD, CALIFORNIA, IS DESCRIBED. OF GENERAL CONCERN WAS THE PREPARATION OF CULTURALLY DEPRIVED CHILDREN FOR SCHOOL EXPERIENCES AND FOR FUTURE EMPLOYMENT. A MAJOR GOAL WAS TO IMPROVE THE SELF-IMAGE OF THE CHILDREN AND TO ASSIST THE PARENTS AND CHILDREN IN PROVIDING…

INTRA-UNDULATOR MEASUREMENTS AT VISA FEL.

DOE Office of Scientific and Technical Information (OSTI.GOV)

MUROKH,A.; FRIGOLA,P.; ET AL

2000-08-13

We describe a diagnostics system developed, to measure exponential gain properties and the electron beam dynamics inside the strong focusing 4-m long undulator for the VISA (Visible to Infrared SASE Amplifier) FEL. The technical challenges included working inside the small undulator gap, optimizing the electron beam diagnostics in the high background environment of the spontaneous undulator radiation, multiplexing and transporting the photon beam. Initial results are discussed.

Intra-undulator measurements at VISA FEL

DOE Office of Scientific and Technical Information (OSTI.GOV)

Murokh, A; Frigola, P; Pellegrini, C

2000-08-10

We describe a diagnostics system developed, to measure exponential gain properties and the electron beam dynamics inside the strong focusing 4-m long undulator for the VISA (Visible to Infrared SASE Amplifier) FEL. The technical challenges included working inside the small undulator gap, optimizing the electron beam diagnostics in the high background environment of the spontaneous undulator radiation, multiplexing and transporting the photon beam. Initial results are discussed.

Bunch Length Measurements at the JLab FEL Using Coherent Transition and Synchrotron Radiation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pavel Evtushenko; James Coleman; Kevin Jordan

2006-05-01

The JLab FEL is routinely operated with sub-picosecond bunches. The short bunch length is important for high gain of the FEL. Coherent transition radiation has been used for the bunch length measurements for many years [1]. This diagnostic can be used only in the pulsed beam mode. It is our goal to run the FEL with CW beam and a 74.85 MHz micropulse repetition rate, which, with the 135 pC nominal bunch charge corresponds to the beam average current of 10 mA. Hence it is very desirable to have the possibility of making bunch length measurements when running CW beammore » with any micropulse frequency. We use a Fourier transform infrared (FTIR) interferometer, which is essentially a Michelson interferometer, to measure the spectrum of the coherent synchrotron radiation generated in the last dipole of the magnetic bunch compressor upstream of the FEL wiggler. This noninvasive diagnostic provides bunch length measurements for CW beam operation at any micropulse frequency. We also compare the measurements made with the help of the FTIR interferometer with data obtained using the Martin-Puplett interferometer [1]. Results of the two diagnostics agree within 15 %. Here we present a description of the experimental setup, data evaluation procedure and results of the beam measurements.« less

Bunch Length Measurements at the JLab FEL Using Coherent Transition and Synchrotron Radiation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Evtushenko, P.; Coleman, J.; Jordan, K.

2006-11-20

The JLab FEL is routinely operated with sub-picosecond bunches. The short bunch length is important for high gain of the FEL. Coherent transition radiation has been used for the bunch length measurements for many years. This diagnostic can be used only in the pulsed beam mode. It is our goal to run the FEL with CW beam and a 74.85 MHz micropulse repetition rate, which, with the 135 pC nominal bunch charge corresponds to the beam average current of 10 mA, Hence it is very desirable to have the possibility of making bunch length measurements when running CW beam withmore » any micropulse frequency. We use a Fourier transform infrared (FTIR) interferometer, which is essentially a Michelson interferometer, to measure the spectrum of the coherent synchrotron radiation generated in the last dipole of the magnetic bunch compressor upstream of the FEL wiggler. This noninvasive diagnostic provides bunch length measurements for CW beam operation at any micropulse frequency. We also compare the measurements made with the help of the FTIR interferometer with data obtained using the Martin-Puplett interferometer. Results of the two diagnostics agree within 15 %. Here we present a description of the experimental setup, data evaluation procedure and results of the beam measurements.« less

Harmonium: An Ultrafast Vacuum Ultraviolet Facility.

PubMed

Arrell, Christopher A; Ojeda, José; Longetti, Luca; Crepaldi, Alberto; Roth, Silvan; Gatti, Gianmarco; Clark, Andrew; van Mourik, Frank; Drabbels, Marcel; Grioni, Marco; Chergui, Majed

2017-05-31

Harmonium is a vacuum ultraviolet (VUV) photon source built within the Lausanne Centre for Ultrafast Science (LACUS). Utilising high harmonic generation, photons from 20-110 eV are available to conduct steady-state or ultrafast photoelectron and photoion spectroscopies (PES and PIS). A pulse preserving monochromator provides either high energy resolution (70 meV) or high temporal resolution (40 fs). Three endstations have been commissioned for: a) PES of liquids; b) angular resolved PES (ARPES) of solids and; c) coincidence PES and PIS of gas phase molecules or clusters. The source has several key advantages: high repetition rate (up to 15 kHz) and high photon flux (1011 photons per second at 38 eV). The capabilities of the facility complement the Swiss ultrafast and X-ray community (SwissFEL, SLS, NCCR MUST, etc.) helping to maintain Switzerland's leading role in ultrafast science in the world.

Feasibility of an XUV FEL Oscillator Driven by a SCRF Linear Accelerator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lumpkin, A. H.; Freund, H. P.; Reinsch, M.

The Advanced Superconducting Test Accelerator (ASTA) facility is currently under construction at Fermi National Accelerator Laboratory. Using a1-ms-long macropulse composed of up to 3000 micropulses, and with beam energies projected from 45 to 800 MeV, the possibility for an extreme ultraviolet (XUV) free-electron laser oscillator (FELO) with the higher energy is evaluated. We have used both GINGER with an oscillator module and the MEDUSA/OPC code to assess FELO saturation prospects at 120 nm, 40 nm, and 13.4 nm. The results support saturation at all of these wavelengths which are also shorter than the demonstrated shortest wavelength record of 176 nmmore » from a storage-ring-based FELO. This indicates linac-driven FELOs can be extended into this XUV wavelength regime previously only reached with single-pass FEL configurations.« less

R&D for a Soft X-Ray Free Electron Laser Facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Corlett, John; Attwood, David; Byrd, John

2009-06-08

Several recent reports have identified the scientific requirements for a future soft x-ray light source, and a high-repetition-rate free-electron laser (FEL) facility that is responsive to these requirements is now on the horizon. R&D in some critical areas is needed, however, to demonstrate technical performance, thus reducing technical risks and construction costs. Such a facility most likely will be based on a CW superconducting linear accelerator with beam supplied by a high-brightness, high-repetition-rate photocathode electron gun operating in CW mode, and on an array of FELs to which the accelerated beam is distributed, each operating at high repetition rate andmore » with even pulse spacing. Dependent on experimental requirements, the individual FELs can be configured for either self-amplified spontaneous emission (SASE), seeded, or oscillator mode of operation, including the use of high-gain harmonic generation (HGHG), echo-enhanced harmonic generation (EEHG), harmonic cascade, or other configurations. In this White Paper we identify the overall accelerator R&D needs, and highlight the most important pre-construction R&D tasks required to value-engineer the design configuration and deliverables for such a facility. In Section 1.4 we identify the comprehensive R&D ultimately needed. We identify below the highest-priority requirements for understanding machine performance and reduce risk and costs at this pre-conceptual design stage. Details of implementing the required tasks will be the subject of future evaluation. Our highest-priority R&D program is the injector, which must be capable of delivering a beam with bunches up to a nanocoulomb at MHz repetition rate and with normalized emittance {le} 1 mm {center_dot} mrad. This will require integrated accelerating structure, cathode, and laser systems development. Cathode materials will impact the choice of laser technology in wavelength and energy per pulse, as well as vacuum requirements in the

Performance of a Combined System Using an X-Ray FEL Oscillator and a High-Gain FEL Amplifier

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gupta, L.; Lindberg, R.; Kim, K. -J.

The LCLS-II at SLAC will feature a 4 GeV CW superconducting (SC) RF linac [1] that can potentially drive a 5th harmonic X-Ray FEL Oscillator (XFELO) to produce fully coherent, 1 MW photon pulses with a 5 meV bandwidth at 14.4 keV [2]. The XFELO output can serve as the input seed signal for a high-gain FEL amplifier employing fs electron beams from the normal conducting SLAC linac, thereby generating coherent, fs x-ray pulses with TW peak powers using a tapered undulator after saturation [3]. Coherent, intense output at several tens of keV will also be feasible if one considersmore » a harmonic generation scheme. Thus, one can potentially reach the 42 keV photon energy required for the MaRIE project [4] by beginning with an XFELO operating at the 3rd harmonic to produce 14.0 keV photons using a 12 GeV SCRF linac, and then subsequently using the high-gain harmonic generation scheme to generate and amplify the 3th harmonic at 42 keV [5]. We report extensive GINGER simulations that determine an optimized parameter set for the combined system.« less

Enhancement of Permeation in Transdermal Drug Delivery System by 6μm Wavelength Area Using an MIR-FEL

NASA Astrophysics Data System (ADS)

Uchizono, T.; Ishii, K.; Iwao, Y.; Itou, Y.; Maruo, H.; Hori, M.; Awazu, K.

2005-03-01

Ablation of the stratum corneum (SC) by pulsed-laser irradiation is one method of enhancing transdermal drug delivery (TD). For non-invasive laser TD treatment, we have tried to enhance TD without ablation of the SC using an MIR-FEL (6-μm wavelength) (FEL : free electron laser). Lidocaine was used as the drug in this study. The enhancement of TD was measured by HPLC. It was found that the lidocaine TD of the sample irradiated by MIR-FEL was enhanced 10 fold faster than the non-irradiated sample with a flux at 0.5 μg/cm2/h, measured by HPLC. We have demonstrated the effectiveness of TD enhancement by an MIR-FEL (6-μm wavelength) irradiation.

A helical optical for circular polarized UV-FEL project at the UVSOR

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hama, Hiroyuki

1995-12-31

Most of existing storage ring free electron lasers (SRFEL) are restricted those performances by degradation of mirrors in optical cavities. In general, the SRFEL gain at the short wavelength region with high energy electrons is quite low, and the high reflectivity mirrors such as dielectric multilayer mirrors are therefore required. The mirror degradation is considered as a result of irradiation of higher harmonic photons that are simultaneously emitted from planar optical klystron (OK) type undulators, which are commonly used in SRFEL. This problem is getting severer as the lasing wavelength becomes shorter. The UVSOR-FEL had been originally scheduled to bemore » shutdown by 1996 because another undulator project for spectroscopic studies with circular polarized photon would take the FEL`s place. According to suggestion of the insertion device group of the SPring-8, we have designed a helical undulator that is able to vary degree and direction of the polarization easily. In addition, the undulator can be converted into a helical OK by replacing magnets at the center part of undulator in order to coexist with further FEL experiments. Using a calculated magnetic field for magnet configurations of the OK mode, the radiation spectrum at wide wavelength range was simulated by a Fourier transform of Lienard-Wiechert potentials. As a matter of course, some higher harmonics are radiated on the off-axis angle. However it was found out that the higher harmonics is almost negligible as far as inside a solid angle of the Gaussian laser mode. Moreover the gain at the UV region of 250 nm is expected to be much higher than our present FEL because of high brilliant fundamental radiation. The calculated spatial distribution of higher harmonics and the estimated instantaneous gain is presented. Advantages of the helical OK for SRFEL will be discussed in view of our experience, and a possibility of application two-color experiment with SR will be also mentioned.« less

The ETA-2 induction linac as a high average power FEL driver

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nexsen, W.E.; Atkinson, D.P.; Barrett, D.M.

1989-10-16

The Experimental Test Accelerator-II (ETA-II) is the first induction linac designed specifically to FEL requirements. It primarily is intended to demonstrate induction accelerator technology for high average power, high brightness electron beams, and will be used to drive a 140 and 250 GHz microwave FEL for plasma heating experiments in the Microwave Tokamak Experiment (MTX) at LLNL. Its features include high vacuum design which allows the use of an intrinsically bright dispenser cathode, induction cells designed to minimize BBU growth rate, and careful attention to magnetic alignment to minimize radial sweep due to beam corkscrew. The use of magnetic switchesmore » allows high average power operation. At present ETA-II is being used to drive 140 GHz plasma heating experiments. These experiments require nominal beam parameters of 6 Mev energy, 2kA current, 20ns pulse width and a brightness of 1 {times} 10{sup 8} A/(m-rad){sup 2} at the wiggler with a pulse repetition frequency (PRF) of 0.5 Hz. Future 250 GHz experiments require beam parameters of 10 Mev energy, 3kA current, 50ns pulse width and a brightness of 1 {times} 10{sup 8} A/(m-rad){sup 2} with a 5 kHz PRF for 0.5 sec. In this paper we discuss the present status of ETA-II parameters and the phased development program necessary to satisfy these future requirements. 13 refs., 9 figs., 1 tab.« less

Oscillator Seeding of a High Gain Harmonic Generation FEL in a Radiator-First Configuration

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gandhi, P.; Wurtele, J.; Penn, G.

2012-05-20

A longitudinally coherent X-ray pulse from a high repetition rate free electron laser (FEL) is desired for a wide variety of experimental applications. However, generating such a pulse with a repetition rate greater than 1 MHz is a significant challenge. The desired high repetition rate sources, primarily high harmonic generation with intense lasers in gases or plasmas, do not exist now, and, for the multi-MHz bunch trains that superconducting accelerators can potentially produce, are likely not feasible with current technology. In this paper, we propose to place an oscillator downstream of a radiator. The oscillator generates radiation that is usedmore » as a seed for a high gain harmonic generation (HGHG) FEL which is upstream of the oscillator. For the first few pulses the oscillator builds up power and, until power is built up, the radiator has no HGHG seed. As power in the oscillator saturates, the HGHG is seeded and power is produced. The dynamics and stability of this radiator-first scheme is explored analytically and numerically. A single-pass map is derived using a semi-analytic model for FEL gain and saturation. Iteration of the map is shown to be in good agreement with simulations. A numerical example is presented for a soft X-ray FEL.« less

A 1kW EUV source for lithography based on FEL emission in a compact storage ring

NASA Astrophysics Data System (ADS)

Feser, Michael; Ruth, Ron; Loewen, Rod

2017-10-01

EUV has long been hailed as the next generation lithography technology. Its adoption into high volume manufacturing (HVM), however, has been delayed several technology nodes due to technical issues, many of which can be attributed to the EUV source performance. Today's EUV lithography scanners are powered by laser produce plasma (LPP) sources. They have issues with power scaling beyond 300 W, reliability and contamination. Free Electron Lasers (FELs) have been considered as an alternative EUV source. Advantages of accelerator based sources are the maturity of the accelerator technology, lack of debris/contamination, and ability to provide high power. Industry turned away from this technology because of the requirement to feed up to 10 scanners from one linear FEL to make it economically feasible, the large footprint, and generation of radioactive byproducts. All of these issues are overcome in the presented concept using a compact storage ring with steady-state FEL lasing action. At 1 kW output power, comparable cost and footprint to an LPP source, this source is ideally suited for use on a single scanner and promises reliable, contamination free operation. FEL action in the storage ring is sustained by operating the FEL well below the saturation regime and preserving the equilibrium low emittance and energy distribution of the ring.

FEL-FTIR spectroscopy of matrix-isolated formic acid

NASA Astrophysics Data System (ADS)

Henderson, Don O.; Mu, Richard; Silberman, Enrique; Berryman, Kenneth W.; Rella, Chris W.

1994-07-01

Infrared spectral hole burning studies have provided a wealth of information concerning site reorientation of defects in solids and vibrational relaxation dynamics. The most investigated systems appear to be impurities trapped in alkali halides. Limited studies on molecules trapped in noble gas matrices have demonstrated that these systems are good candidates for investigating persistent spectral holes. However, most infrared spectral hole burning studies have been limited by the tunability of commercially available infrared lasers which in turn restricts the spectral feature which can be burned. On the other hand, the tunability of Infrared Free Electron Lasers (IR-FELs) allows for targeting radiation into vibrational of the molecular system under study. We have used the Free Electron Laser-Fourier Transform Infrared Spectroscopy to investigate infrared hole burning of formic acid (HCOOD) isolated in an Ar matrix at a matrix/sample ratio of 4000/1. The results of the FEL radiation tuned to v2 mode of HCOOD are discussed together with matrix induced frequency shifts and matrix induced band splittings.

The effect of Fel d 1-derived T-cell peptides on upper and lower airway outcome measurements in cat-allergic subjects.

PubMed

Alexander, C; Tarzi, M; Larché, M; Kay, A B

2005-10-01

We previously showed that overlapping Fel d 1-derived T-cell peptides inhibited surrogate markers of allergy (i.e. early and late-phase skin reactions and T-cell function) in cat allergic subjects. The present pilot study was designed to determine whether this treatment affected clinically relevant outcome measurements such as the allergen-induced nasal and bronchial reactions, and asthma/rhinitis quality of life (QOL). Sixteen cat-allergic asthmatic subjects who gave a dual (early and late) asthmatic response (DAR) to inhaled cat allergen were randomly assigned to receive either Fel d 1 peptides (approximately 300 mug in increasing, divided doses) or placebo (8 active : 8 placebo). Twelve single early responders (SER) were also studied in an open fashion design. Allergen-induced bronchial and nasal measurements as well as the QOL was measured at baseline, 4-8 weeks (follow-up 1 (FU1)) and 3-4 months (FU2). In the active, but not placebo, group there were significant decreases in the late asthmatic reaction (LAR) to whole cat dander (P = 0.03) at FU2 but with no between group difference. There were also significant improvements in asthma quality of life (QOL) scores [asthma-activity limitation (P = 0.014); rhinitis-sleep (P = 0.024), non-nose/non-eye symptoms (P = 0.031), nasal problems (P = 0.015)]. In the open study Fel d 1 peptide treatment resulted in significant decreases in number of sneezes (P = 0.05), weight of nasal secretions (P = 0.04) and nasal blockage (P = 0.01) following allergen challenge. Multiple, short, overlapping Fel d 1 T-cell peptides have potential for inhibiting upper and lower airway outcome measurements in cat allergic patients. Larger, dose-ranging, studies are required before firm conclusions on clinical efficacy of peptide allergen therapy can be made.

Formation of disulfide bonds and homodimers of the major cat allergen Fel d 1 equivalent to the natural allergen by expression in Escherichia coli.

PubMed

Grönlund, Hans; Bergman, Tomas; Sandström, Kristofer; Alvelius, Gunvor; Reininger, Renate; Verdino, Petra; Hauswirth, Alexander; Liderot, Karin; Valent, Peter; Spitzauer, Susanne; Keller, Walter; Valenta, Rudolf; van Hage-Hamsten, Marianne

2003-10-10

Dander from the domestic cat (Felis domesticus) is one of the most common causes of IgE-mediated allergy. Attempts to produce tetrameric folded major allergen Fel d 1 by recombinant methods with structural features similar to the natural allergen have been only partially successful. In this study, a recombinant folded Fel d 1 with molecular and biological properties similar to the natural counterpart was produced. A synthetic gene coding for direct fusion of the Fel d 1 chain 2 N-terminally to chain 1 was constructed by overlapping oligonucleotides in PCR. Escherichia coli expression resulted in a non-covalently associated homodimer with an apparent molecular mass of 30 kDa defined by size exclusion chromatography. Furthermore, each 19,177-Da subunit displayed a disulfide pattern identical to that found in the natural Fel d 1, i.e. Cys3(1) Cys73(2), Cys44(1)-Cys48(2), Cys70(1)-Cys7(2), as determined by electrospray mass spectrometry after tryptic digestion. Circular dichroism analysis showed identical folds of natural and recombinant Fel d 1. Furthermore, recombinant Fel d l reacted specifically with serum IgE, inducing expression of CD203c on basophils and lymphoproliferative responses in cat-allergic patients. The results show that the overall fold and immunological properties of the recombinant Fel d 1 are very similar to those of natural Fel d 1. Moreover, the recombinant Fel d 1 construct provides a tool for defining the three-dimensional structure of Fel d 1 and represents a reagent for diagnosis and allergen-specific immunotherapy of cat allergy.

Output characteristics of SASE-driven short wavelength FEL`s

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fawley, W.M.

This paper investigates various properties of the ``microspikes`` associated with self-amplified spontaneous emission (SASE) in a short wavelength free-electron laser (FEL). Using results from the 2-D numerical simulation code GINGER, we confirm theoretical predictions such as the convective group velocity in the exponential gain regime. In the saturated gain regime beyond the initial saturation, we find that the average radiation power continues to grow with an approximately linearly dependence upon undulator length. Moreover, the spectrum significantly broadens and shifts in wavelength to the redward direction, with{ital P(w)} approaching a constant, asymptotic value. This is in marked contrast to the exponentialmore » gain regime where the spectrum steadily narrows, {ital P(w)} grows, and the central wavelength remains constant with {ital z}. Via use of a spectrogram diagnostic {ital S(w,t)}, it appears that the radiation pattern in the saturated gain regime is composed of an ensemble of distinct ``sinews`` whose widths AA remain approximately constant but whose central wavelengths can ``chirp`` by varying a small extent with {ital t}.« less

Dispersion relations for 1D high-gain FELs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Webb, S.D.; Litvinenko, V.N.

2010-08-23

We present analytical results for the one-dimensional dispersion relation for high-gain FELs. Using kappa-n distributions, we obtain analytical relations between the dispersion relations for various order kappa distributions. Since an exact solution exists for the kappa-1 (Lorentzian) distribution, this provides some insight into the number of modes on the way to the Gaussian distribution.

Serial snapshot crystallography for materials science with SwissFEL

DOE PAGES

Dejoie, Catherine; Smeets, Stef; Baerlocher, Christian; ...

2015-04-21

New opportunities for studying (sub)microcrystalline materials with small unit cells, both organic and inorganic, will open up when the X-ray free electron laser (XFEL) presently being constructed in Switzerland (SwissFEL) comes online in 2017. Our synchrotron-based experiments mimicking the 4%-energy-bandpass mode of the SwissFEL beam show that it will be possible to record a diffraction pattern of up to 10 randomly oriented crystals in a single snapshot, to index the resulting reflections, and to extract their intensities reliably. The crystals are destroyed with each XFEL pulse, but by combining snapshots from several sets of crystals, a complete set of datamore » can be assembled, and crystal structures of materials that are difficult to analyze otherwise will become accessible. Even with a single shot, at least a partial analysis of the crystal structure will be possible, and with 10–50 femtosecond pulses, this offers tantalizing possibilities for time-resolved studies.« less

Temporal profile measurements of relativistic electron bunch based on wakefield generation

DOE PAGES

Bettoni, S.; Craievich, P.; Lutman, A. A.; ...

2016-02-25

A complete characterization of the time-resolved longitudinal beam phase space is important to optimize the final performances of an accelerator, and in particular this is crucial for Free Electron Laser (FEL) facilities. In this study we propose a novel method to characterize the profile of a relativistic electron bunch by passively streaking the beam using its self-interaction with the transverse wakefield excited by the bunch itself passing off-axis through a dielectric-lined or a corrugated waveguide. Results of a proof-of-principle experiment at the SwissFEL Injector Test Facility are discussed.

Development of an alternative testing strategy for the fish early life-stage (FELS) test using the AOP framework

EPA Science Inventory

Currently, the fish early life-stage (FELS) test (OECD 210) is the primary guideline used to estimate chronic toxicity of regulated chemicals. Although already more cost-efficient than adult fish tests, the FELS test has some important drawbacks. Both industry and regulatory inst...

Two-gigawatt burst-mode operation of the intense microwave prototype (IMP) free-electron laser (FEL) for the microwave tokamak experiment (MTX)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Felker, B.; Allen, S.; Bell, H.

1993-10-06

The MTX explored the plasma heating effects of 140 GHz microwaves from both Gyrotrons and from the IMP FEL wiggler. The Gyrotron was long pulse length (0.5 seconds maximum) and the FEL produced short-pulse length, high-peak power, single and burst modes of 140 GHZ microwaves. Full-power operations of the IMP FEL wiggler were commenced in April of 1992 and continued into October of 1992. The Experimental Test Accelerator H (ETA-II) provided a 50-nanosecond, 6-MeV, 2--3 kAmp electron beam that was introduced co-linear into the IMP FEL with a 140 GHz Gyrotron master oscillator (MO). The FEL was able to amplifymore » the MO signal from approximately 7 kW to peaks consistently in the range of 1--2 GW. This microwave pulse was transmitted into the MTX and allowed the exploration of the linear and non-linear effects of short pulse, intense power in the MTX plasma. Single pulses were used to explore and gain operating experience in the parameter space of the IMP FEL, and finally evaluate transmission and absorption in the MTX. Single-pulse operations were repeatable. After the MTX was shut down burst-mode operations were successful at 2 kHz. This paper will describe the IMP FEL, Microwave Transmission System to MTX, the diagnostics used for calorimetric measurements, and the operations of the entire Microwave system. A discussion of correlated and uncorrelated errors that affect FEL performance will be made Linear and non-linear absorption data of the microwaves in the MTX plasma will be presented.« less

LCLS X-Ray FEL Output Performance in the Presence of Highly Time-Dependent Undulator Wakefields

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fawley, W.M.; /LBL, Berkeley; Bane, K.L.F.

Energy loss due to wakefields within a long undulator, if not compensated by an appropriate tapering of the magnetic field strength, can degrade the FEL process by detuning the resonant FEL frequency. The wakefields arise from the vacuum chamber wall resistivity, its surface roughness, and abrupt changes in its aperture. For LCLS parameters, the resistive-wall component is the most critical and depends upon the chamber material (e.g., Cu) and its radius. Of recent interest[1] is the so-called ''AC'' component of the resistive-wall wake which can lead to strong variations on very short timescales (e.g., {approx} 20 fs). To study themore » expected performance of the LCLS in the presence of these wakefields, we have made an extensive series of start-to-end SASE simulations with tracking codes PARMELA and ELEGANT, and time-dependent FEL simulation codes GENESIS1.3 and GINGER. We discuss the impact of the wakefield losses upon output energy, spectral bandwidth, and temporal envelope of the output FEL pulse, as well as the benefits of a partial compensation of the time-dependent wake losses obtained with a slight z-dependent taper in the undulator field. We compare the taper results to those predicted analytically[2].« less

LCLS X-Ray FEL Output Performance in the Presence of HighlyTime-Dependent Undulator Wakefields

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bane, Karl L.F.; Emma, Paul; Huang, Heinz-Dieter Nuhn

Energy loss due to wakefields within a long undulator, if not compensated by an appropriate tapering of the magnetic field strength, can degrade the FEL process by detuning the resonant FEL frequency. The wakefields arise from the vacuum chamber wall resistivity, its surface roughness, and abrupt changes in its aperture. For LCLS parameters, the resistive-wall component is the most critical and depends upon the chamber material (e.g., Cu) and its radius. Of recent interest[1] is the so-called ''AC'' component of the resistive-wall wake which can lead to strong variations on very short timescales (e.g., {approx} 20 0fs). To study themore » expected performance of the LCLS in the presence of these wakefields, we have made an extensive series of start-to-end SASE simulations with tracking codes PARMELA and ELEGANT, and time-dependent FEL simulation codes GENESIS1.3 and GINGER. We discuss the impact of the wakefield losses upon output energy, spectral bandwidth, and temporal envelope of the output FEL pulse, as well as the benefits of a partial compensation of the time-dependent wake losses obtained with a slight z-dependent taper in the undulator field. We compare the taper results to those predicted analytically[2].« less

Optimization of the LCLS X-Ray FEL Output Performance in the Presence of Strong Undulator Wakefields

DOE Office of Scientific and Technical Information (OSTI.GOV)

Reiche, S.; /UCLA; Bane, K.L.F.

The Linac Coherent Light Source (LCLS) Free-Electron Laser will operate in the wavelength range of 1.5 to 15 Angstroms. Energy loss due to wakefields within the long undulator can degrade the FEL process by detuning the resonant FEL frequency. The wakefields arise from the vacuum chamber wall resistivity, its surface roughness, and abrupt changes in its aperture. For LCLS parameters, the resistive component is the most critical and depends upon the chamber material (e.g. Cu) and its radius. To study the expected performance in the presence of these wakefields, we make a series of start-to-end simulations with tracking codes PARMELAmore » and ELEGANT and time-dependent FEL simulation codes Genesis 1.3 and Ginger. We discuss the impact of the wakefield on output energy, spectral bandwidth, and temporal envelope of the output FEL pulse, as well as the benefits of a partial compensation obtained with a slight z dependent taper in the undulator field. We compare these results to those obtained by decreasing the bunch charge or increasing the vacuum chamber radius. We also compare our results to those predicted in concurrent analytical work.« less

ETHERNET BASED EMBEDDED SYSTEM FOR FEL DIAGNOSTICS AND CONTROLS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jianxun Yan; Daniel Sexton; Steven Moore

2006-10-24

An Ethernet based embedded system has been developed to upgrade the Beam Viewer and Beam Position Monitor (BPM) systems within the free-electron laser (FEL) project at Jefferson Lab. The embedded microcontroller was mounted on the front-end I/O cards with software packages such as Experimental Physics and Industrial Control System (EPICS) and Real Time Executive for Multiprocessor System (RTEMS) running as an Input/Output Controller (IOC). By cross compiling with the EPICS, the RTEMS kernel, IOC device supports, and databases all of these can be downloaded into the microcontroller. The first version of the BPM electronics based on the embedded controller wasmore » built and is currently running in our FEL system. The new version of BPM that will use a Single Board IOC (SBIOC), which integrates with an Field Programming Gate Array (FPGA) and a ColdFire embedded microcontroller, is presently under development. The new system has the features of a low cost IOC, an open source real-time operating system, plug&play-like ease of installation and flexibility, and provides a much more localized solution.« less

Status Report on the CEBAF IR and UV FELs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Leemann, Christoph; Bisognano, Joseph; Douglas, David

1993-07-01

The CEBAF five pass recirculating, superconducting linac, being developed as a high power electron source for nuclear physics, is also an ideal FEL driver.The 45 MeV front end linac is presently operational with a CW (low peak current) nuclear physics gun and has met all CEBAF performance specifications including low emittance and energy spread (< 1 * 10^-4). Progress will be reported in commissioning.This experience leads to predictions of excellent FEL performance.Initial designs reported last year have been advanced.Using the output of a high charge DC photoemission gun under development with a 6 cm period wiggler produces kilowatt output powersmore » in the 3.6 to 17 micrometer range in the fundamental.Third harmonic operation extends IR performance down to 1.2 micrometer.Beam at energies up to 400 MeV from the first full CEBAF linac will interact in a similar but longer wiggler to yield kilowatt UV light production at wavelengths as short as 0.15 micrometers.Full power FEL« less

Self-seeded injection-locked FEL amplifer

DOEpatents

Sheffield, Richard L.

1999-01-01

A self-seeded free electron laser (FEL) provides a high gain and extraction efficiency for the emitted light. An accelerator outputs a beam of electron pulses to a permanent magnet wiggler having an input end for receiving the electron pulses and an output end for outputting light and the electron pulses. An optical feedback loop collects low power light in a small signal gain regime at the output end of said wiggler and returns the low power light to the input end of the wiggler while outputting high power light in a high signal gain regime.

Development of BPM Electronics at the JLAB FEL

NASA Astrophysics Data System (ADS)

Sexton, D.; Evtushenko, P.; Jordan, K.; Yan, J.; Dutton, S.; Moore, W.; Evans, R.; Coleman, J.

2006-11-01

A new version of BPM electronics based on the AD8362 RMS detector, which is a direct RF to DC converter, is under development at the JLAB FEL. Each of these new BPM electronics utilizes an embedded ColdFire Microprocessor for data processing and communication with the EPICS control system via TCP/IP. The ColdFire runs RTEMS, which is an open source real-time operating system. The JLAB FEL is a SRF Energy Recovery LINAC capable of running up to 10 mA CW beam with a 74.85 MHz micropulse frequency. For diagnostic reasons and for machine tune up, the micropulse frequency can be reduced to 1.17 MHz, which corresponds to about 160 μA of beam current. It is required that the BPM system would be functional for all micropulse frequencies. By taking into account the headroom for the beam steering and current variations the dynamic range of the RF front end is required to be about 60 dB. A BPM resolution of at least 100 μm is required, whereas better resolution is very desirable to make it possible for more accurate measurements of the electron beam optics. Some results of the RF front end development are presented as well as the first measurements made with an electron beam.

Diffraction and pulse slippage in the Boeing 1 kW FEL oscillator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Blau, J.; Wong, R.K.; Colson, W.B.

1995-12-31

A four-dimensional simulation in x, y, z, and t, including betatron motion of the electrons, is used to study the combined effects of diffraction, pulse slippage and desynchronism in the Boeing 1 kW FEL oscillator.

Een Meetsysteem voor het Testen van Radiocommunicatie-Apparatuur (A measuring Facility for Testing of Radio Communication Equipment)

DTIC Science & Technology

1991-08-01

insert various jamming signals. The criterion for classifying radio equipment under test is the quality of transferred information , that is the SINAD...UNCLASSFED) This report describes a test facility for measuring the behaviour and quality of radio communication equipment in a simulated operational...formation FEL has the disposal of a facility to test the quality of radio equipment in a simulated operational situation. (Y .. ,. -’ , / " " ’ TNO mppon 4

Development of BPM Electronics at the JLAB FEL

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sexton, D.; Evtushenko, P.; Jordan, K.

2006-11-20

A new version of BPM electronics based on the AD8362 RMS detector, which is a direct RF to DC converter, is under development at the JLAB FEL. Each of these new BPM electronics utilizes an embedded ColdFire Microprocessor for data processing and communication with the EPICS control system via TCP/IP. The ColdFire runs RTEMS, which is an open source real-time operating system. The JLAB FEL is a SRF Energy Recovery LINAC capable of running up to 10 mA CW beam with a 74.85 MHz micropulse frequency. For diagnostic reasons and for machine tune up, the micropulse frequency can be reducedmore » to 1.17 MHz, which corresponds to about 160 {mu}A of beam current. It is required that the BPM system would be functional for all micropulse frequencies. By taking into account the headroom for the beam steering and current variations the dynamic range of the RF front end is required to be about 60 dB. A BPM resolution of at least 100 {mu}m is required, whereas better resolution is very desirable to make it possible for more accurate measurements of the electron beam optics. Some results of the RF front end development are presented as well as the first measurements made with an electron beam.« less

Development of BPM Electronics at the JLAB FEL

DOE Office of Scientific and Technical Information (OSTI.GOV)

Daniel Sexton; Pavel Evtushenko; Kevin Jordan

2006-05-01

A new version of BPM electronics based on the AD8362 RMS detector, which is a direct RF to DC converter, is under development at the JLAB FEL. Each of these new BPM electronics utilizes an embedded ColdFire Microprocessor for data processing and communication with the EPICS control system via TCP/IP. The ColdFire runs RTEMS, which is an open source real-time operating system. The JLAB FEL is a SRF Energy Recovery LINAC capable of running up to 10 mA CW beam with the micropulse up to 74.85 MHz. For diagnostic reasons and for the machine tune up, the micropulse frequency canmore » be reduced to 1.17 MHz, which corresponds to about 160 ?A of beam current. It is required that the BPM system would be functional for all micropulse frequencies. By taking into account the headroom for the beam steering and current variations the dynamic range of the RF front end is required to be about 60 dB. A BPM resolution of at least 100 ?m is required, whereas better resolution is very desirable to make it possible for more accurate measurements of the electron beam optics. Some results of the RF front end development are presented as well as the first measurements made with an electron beam.« less

Analysis Of The Boeing FEL Mirror Measurements

NASA Astrophysics Data System (ADS)

Knapp, Charles E.; Viswanathan, Vriddhachalam K.; Appert, Quentin D.

1989-07-01

The aberrations have been measured for the finished mirrors that are part of the Burst Mode ring resonator of the Free Electron Laser (FEL) being constructed at the Boeing Aerospace Company in Seattle, Washington. This paper presents analysis of these measurements using the GLAD code, a diffraction ray-tracing code. The diffraction losses within the resonator due to the aberrations are presented. The analysis was conducted in two different modes, a paraxial approximation and a full 3-D calculation, and good agreement between the two approaches is shown. Finally, a proposed solution to the problems caused by the aberrations is presented and analyzed.

Fels-Rand: an Xlisp-Stat program for the comparative analysis of data under phylogenetic uncertainty.

PubMed

Blomberg, S

2000-11-01

Currently available programs for the comparative analysis of phylogenetic data do not perform optimally when the phylogeny is not completely specified (i.e. the phylogeny contains polytomies). Recent literature suggests that a better way to analyse the data would be to create random trees from the known phylogeny that are fully-resolved but consistent with the known tree. A computer program is presented, Fels-Rand, that performs such analyses. A randomisation procedure is used to generate trees that are fully resolved but whose structure is consistent with the original tree. Statistics are then calculated on a large number of these randomly-generated trees. Fels-Rand uses the object-oriented features of Xlisp-Stat to manipulate internal tree representations. Xlisp-Stat's dynamic graphing features are used to provide heuristic tools to aid in analysis, particularly outlier analysis. The usefulness of Xlisp-Stat as a system for phylogenetic computation is discussed. Available from the author or at http://www.uq.edu.au/~ansblomb/Fels-Rand.sit.hqx. Xlisp-Stat is available from http://stat.umn.edu/~luke/xls/xlsinfo/xlsinfo.html. s.blomberg@abdn.ac.uk

Optimization for Single-Spike X-Ray FELs at LCLS with a Low Charge Beam

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, L.; Ding, Y.; Huang, Z.

2011-12-14

full-compression mode, although the photon number is less than that from under-compression or over-compression mode. Since we cannot measure the x-ray pulse length at this time scale, the machine is typically optimized for generating maximum photons, not minimum pulse length. In this paper, we study the methods of producing femtosecond (or single-spike) x-ray pulses at LCLS with 20 pC charge, based on start-to-end simulations. Figure 1 shows a layout of LCLS. The compression in the second bunch compressor (BC2) determines the final e-beam bunch length. However, the laser heater, dog-leg after the main linac (DL2) and collective effects also affect the final bunch length. To adjust BC2 compression, we can either change the L2 phase or BC2 R{sub 56}. In this paper we only tune L2 phase while keep BC2 R{sub 56} fixed. For the start-to-end simulations, we used IMPACT-T and ELEGANT tracking from the photocathode to the entrance of the undulator, after that the FEL radiation was simulated with GENESIS. IMPACT-T tracks about 10{sup 6} particles in the injector part until 135 MeV, including 3D space charge force. The output particles from IMPACT-T are smoothed and increased to 12 x 10{sup 6} to reduce high-frequency numerical noise for subsequent ELEGANT simulations, which include linear and nonlinear transport effects, a 1D transient model of CSR, and longitudinal space charge effects, as well as geometric and resistive wake fields in the accelerator. In GENESIS part, the longitudinal wake field from undulator chamber and longitudinal space field are also included.« less

Another cat and mouse game: Deciphering the evolution of the SCGB superfamily and exploring the molecular similarity of major cat allergen Fel d 1 and mouse ABP using computational approaches

PubMed Central

Pageat, Patrick; Bienboire-Frosini, Cécile

2018-01-01

The mammalian secretoglobin (SCGB) superfamily contains functionally diverse members, among which the major cat allergen Fel d 1 and mouse salivary androgen-binding protein (ABP) display similar subunits. We searched for molecular similarities between Fel d 1 and ABP to examine the possibility that they play similar roles. We aimed to i) cluster the evolutionary relationships of the SCGB superfamily; ii) identify divergence patterns, structural overlap, and protein-protein docking between Fel d 1 and ABP dimers; and iii) explore the residual interaction between ABP dimers and steroid binding in chemical communication using computational approaches. We also report that the evolutionary tree of the SCGB superfamily comprises seven unique palm-like clusters, showing the evolutionary pattern and divergence time tree of Fel d 1 with 28 ABP paralogs. Three ABP subunits (A27, BG27, and BG26) share phylogenetic relationships with Fel d 1 chains. The Fel d 1 and ABP subunits show similarities in terms of sequence conservation, identical motifs and binding site clefts. Topologically equivalent positions were visualized through superimposition of ABP A27:BG27 (AB) and ABP A27:BG26 (AG) dimers on a heterodimeric Fel d 1 model. In docking, Fel d 1-ABP dimers exhibit the maximum surface binding ability of AG compared with that of AB dimers and the several polar interactions between ABP dimers with steroids. Hence, cat Fel d 1 is an ABP-like molecule in which monomeric chains 1 and 2 are the equivalent of the ABPA and ABPBG monomers, respectively. These findings suggest that the biological and molecular function of Fel d 1 is similar to that of ABP in chemical communication, possibly via pheromone and/or steroid binding. PMID:29771985

Another cat and mouse game: Deciphering the evolution of the SCGB superfamily and exploring the molecular similarity of major cat allergen Fel d 1 and mouse ABP using computational approaches.

PubMed

Durairaj, Rajesh; Pageat, Patrick; Bienboire-Frosini, Cécile

2018-01-01

The mammalian secretoglobin (SCGB) superfamily contains functionally diverse members, among which the major cat allergen Fel d 1 and mouse salivary androgen-binding protein (ABP) display similar subunits. We searched for molecular similarities between Fel d 1 and ABP to examine the possibility that they play similar roles. We aimed to i) cluster the evolutionary relationships of the SCGB superfamily; ii) identify divergence patterns, structural overlap, and protein-protein docking between Fel d 1 and ABP dimers; and iii) explore the residual interaction between ABP dimers and steroid binding in chemical communication using computational approaches. We also report that the evolutionary tree of the SCGB superfamily comprises seven unique palm-like clusters, showing the evolutionary pattern and divergence time tree of Fel d 1 with 28 ABP paralogs. Three ABP subunits (A27, BG27, and BG26) share phylogenetic relationships with Fel d 1 chains. The Fel d 1 and ABP subunits show similarities in terms of sequence conservation, identical motifs and binding site clefts. Topologically equivalent positions were visualized through superimposition of ABP A27:BG27 (AB) and ABP A27:BG26 (AG) dimers on a heterodimeric Fel d 1 model. In docking, Fel d 1-ABP dimers exhibit the maximum surface binding ability of AG compared with that of AB dimers and the several polar interactions between ABP dimers with steroids. Hence, cat Fel d 1 is an ABP-like molecule in which monomeric chains 1 and 2 are the equivalent of the ABPA and ABPBG monomers, respectively. These findings suggest that the biological and molecular function of Fel d 1 is similar to that of ABP in chemical communication, possibly via pheromone and/or steroid binding.

Direct measurement of the pulse duration and frequency chirp of seeded XUV free electron laser pulses

NASA Astrophysics Data System (ADS)

Azima, Armin; Bödewadt, Jörn; Becker, Oliver; Düsterer, Stefan; Ekanayake, Nagitha; Ivanov, Rosen; Kazemi, Mehdi M.; Lamberto Lazzarino, Leslie; Lechner, Christoph; Maltezopoulos, Theophilos; Manschwetus, Bastian; Miltchev, Velizar; Müller, Jost; Plath, Tim; Przystawik, Andreas; Wieland, Marek; Assmann, Ralph; Hartl, Ingmar; Laarmann, Tim; Rossbach, Jörg; Wurth, Wilfried; Drescher, Markus

2018-01-01

We report on a direct time-domain measurement of the temporal properties of a seeded free-electron laser pulse in the extreme ultraviolet spectral range. Utilizing the oscillating electromagnetic field of terahertz radiation, a single-shot THz streak-camera was applied for measuring the duration as well as spectral phase of the generated intense XUV pulses. The experiment was conducted at FLASH, the free electron laser user facility at DESY in Hamburg, Germany. In contrast to indirect methods, this approach directly resolves and visualizes the frequency chirp of a seeded free-electron laser (FEL) pulse. The reported diagnostic capability is a prerequisite to tailor amplitude, phase and frequency distributions of FEL beams on demand. In particular, it opens up a new window of opportunities for advanced coherent spectroscopic studies making use of the high degree of temporal coherence expected from a seeded FEL pulse.

Infrared Multiphoton Dissociation Spectroscopy with Free-Electron Lasers: On the Road from Small Molecules to Biomolecules.

PubMed

Jašíková, Lucie; Roithová, Jana

2018-03-07

Infrared multiphoton dissociation (IRMPD) spectroscopy is commonly used to determine the structure of isolated, mass-selected ions in the gas phase. This method has been widely used since it became available at free-electron laser (FEL) user facilities. Thus, in this Minireview, we examine the use of IRMPD/FEL spectroscopy for investigating ions derived from small molecules, metal complexes, organometallic compounds and biorelevant ions. Furthermore, we outline new applications of IRMPD spectroscopy to study biomolecules. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Addressing Physics Grand Challenges Using the Jefferson Lab FEL

NASA Astrophysics Data System (ADS)

Williams, Gwyn P.

2006-11-01

The Jefferson Lab Free Electron Laser[1] is the first of the so-called 4^th generation light sources to go operational. Capable of delivering extraordinarily bright, tunable light in ultrafast pulses from THz[2] through infrared to UV, the facility extends the experimental reach of accelerator-based light-sources by many orders of magnitude. This allows new opportunities to study many of the ``Grand Challenges'' recently defined by the Office of Science, Basic Energy Sciences Division, most of which are concerned with understandings of equilibrium and non-equilibrium behavior of materials in physics, chemistry and biology using precise pump and probe techniques. Specifically, in condensed matter physics, the JLab FEL permits new studies which go beyond earlier studies of reductionist behavior to those which examine emergent behavior. Thus, the understanding of high Tc superconductivity, colossal magneto-resistance, and observations of the breakdown of the Born-Oppenheimer approximation, are examples of collective behavior which is now treated theoretically via the concept of quasiparticles. In this presentation we will describe the dual pathways of light source development and physics challenges, and then show how they are combined in experiments that allow new insights to be developed to understand material function. We will illustrate this with details of the evolution of accelerator-based light sources, and with examples of work performed to date. References: [1] Neil et al. Phys. Rev.Letts 84, 662 (2000). [2] Carr, Martin, McKinney, Neil, Jordan & Williams, Nature 420, 153 (2002).

Quantification of Fel d 1 in house dust samples of cat allergic patients by using monoclonal antibody specific to a novel IgE-binding epitope.

PubMed

Tasaniyananda, Natt; Tungtrongchitr, Anchalee; Seesuay, Watee; Sakolvaree, Yuwaporn; Aiumurai, Pisinee; Indrawattana, Nitaya; Chaicumpa, Wanpen; Sookrung, Nitat

2018-03-01

Avoidance of allergen exposure is an effective measure for preventing naÏve and allergic individuals from sensitization (primary intervention) and disease aggravation (secondary intervention), respectively. Regular monitoring of the allergens in the environment is required for the effective intervention. Thus, there is a need for cost-effective test kits for environmental allergen quantifications. To invent a test kit for quantification of cat major allergen, Fel d 1. A mouse monoclonal antibody (MAb) specific to the newly identified IgE-binding conformational epitope of the cat major allergen (Fel d 1) and rabbit polyclonal IgG to recombinant Fel d 1 were used as allergen capture and detection reagents, respectively. Native Fel d 1 was used in constructing a standard curve. Sixteen of 36 dust samples collected from houses of cat allergic subjects in Bangkok contained Fel d 1 above 0.29 μg/gram of dust which is considered as a novel threshold level for causing cat allergy sensitization or symptoms. Among them, 7 samples contained the allergen exceeding 2.35 μg/gram of dust which is the level that would aggravate asthma. Results of the allergen quantification using the locally made test kit showed strong correlation (r = 0.923) with the allergen quantification using commercialized reagents. The assay using MAb to Fel d 1 IgE-binding epitope of this study has potential application as an economic and practical tool for cat allergy intervention measure especially in localities where health resources are relatively limited.

Moisture-induced phase separation and recrystallization in amorphous solid dispersions.

PubMed

Luebbert, Christian; Sadowski, Gabriele

2017-10-30

Active Pharmaceutical Ingredients (APIs) are often dissolved in polymeric matrices to control the gastrointestinal dissolution and to stabilize the amorphous state of the API. During the pharmaceutical development of new formulations, stability studies via storage at certain temperature and relative humidity (RH) have to be carried out to verify the long-term thermodynamic stability of these formulations against unwanted recrystallization and moisture-induced amorphous-amorphous phase separation (MIAPS). This study focuses on predicting the MIAPS of API/polymer formulations at elevated RH. In a first step, the phase behavior of water-free formulations of ibuprofen (IBU) and felodipine (FEL) combined with the polymers poly(vinyl pyrrolidone) (PVP), poly(vinyl acetate) (PVAC) and poly (vinyl pyrrolidone-co-vinyl acetate) (PVPVA64) was determined experimentally by differential scanning calorimetry (DSC). The phase behavior of these water-free formulations was modeled using the Perturbed-Chain Statistical Associating Fluid Theory (PC-SAFT). Based on this, the API solubility and MIAPS in the above-mentioned formulations at humid conditions was predicted in perfect agreement with the results of two-year lasting stability studies at 25°C/0% RH and 40°C/75% RH. MIAPS was predicted and also experimentally found for the FEL/PVP, FEL/PVPVA64 and IBU/PVP formulations, whereas MIAPS was neither predicted nor measured for the IBU/PVPVA64 system and PVAC-containing formulations. It was thus shown that the results of time-consuming long-term stability tests can be correctly predicted via thermodynamic modeling with PC-SAFT. Copyright © 2017 Elsevier B.V. All rights reserved.

A pixelated x-ray detector for diffraction imaging at next-generation high-rate FEL sources

NASA Astrophysics Data System (ADS)

Lodola, L.; Ratti, L.; Comotti, D.; Fabris, L.; Grassi, M.; Malcovati, P.; Manghisoni, M.; Re, V.; Traversi, G.; Vacchi, C.; Batignani, G.; Bettarini, S.; Forti, F.; Casarosa, G.; Morsani, F.; Paladino, A.; Paoloni, E.; Rizzo, G.; Benkechkache, M. A.; Dalla Betta, G.-F.; Mendicino, R.; Pancheri, L.; Verzellesi, G.; Xu, H.

2017-08-01

The PixFEL collaboration has developed the building blocks for an X-ray imager to be used in applications at FELs. In particular, slim edge pixel detectors with high detection efficiency over a broad energy range, from 1 to 12 keV, have been developed. Moreover, a multichannel readout chip, called PFM2 (PixFEL front-end Matrix 2) and consisting of 32 × 32 cells, has been designed and fabricated in a 65 nm CMOS technology. The pixel pitch is 110 μm, the overall area is around 16 mm2. In the chip, different solutions have been implemented for the readout channel, which includes a charge sensitive amplifier (CSA) with dynamic signal compression, a time-variant shaper and an A-to-D converter with a 10 bit resolution. The CSA can be configured in four different gain modes, so as to comply with photon energies in the 1 to 10 keV range. The paper will describe in detail the channel architecture and present the results from the characterization of PFM2. It will discuss the design of a new version of the chip, called PFM3, suitable for post-processing with peripheral, under-pad through silicon vias (TSVs), which are needed to develop four-side buttable chips and cover large surfaces with minimum inactive area.

Gymnastics in Phase Space

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chao, Alexander Wu; /SLAC

2012-03-01

As accelerator technology advances, the requirements on accelerator beam quality become increasingly demanding. Facing these new demands, the topic of phase space gymnastics is becoming a new focus of accelerator physics R&D. In a phase space gymnastics, the beam's phase space distribution is manipulated and precision tailored to meet the required beam qualities. On the other hand, all realization of such gymnastics will have to obey accelerator physics principles as well as technological limitations. Recent examples of phase space gymnastics include Emittance exchanges, Phase space exchanges, Emittance partitioning, Seeded FELs and Microbunched beams. The emittance related topics of this listmore » are reviewed in this report. The accelerator physics basis, the optics design principles that provide these phase space manipulations, and the possible applications of these gymnastics, are discussed. This fascinating new field promises to be a powerful tool of the future.« less

Booster Applications Facility report, phase 2

NASA Astrophysics Data System (ADS)

Thieberger, P.

1991-06-01

This report summarizes studies and planning performed by Brookhaven National Laboratory (BNL) personnel at the request of NASA for the design, construction and operation of experimental areas and facilities for utilization of ion beams from the BNL Booster synchrotron particle accelerator. These facilities would be primarily utilized to simulate space radiation for radiobiological research, shielding studies and detector calibrations. The feasibility of such a project has been established, preliminary designs and cost estimates have been developed and a formal proposal can be submitted pending DOE concurrence. The main body of this report consists of the material presented by BNL during the meeting with a NASA appointed Panel on December 10 and 11, 1990. The individual speakers have provided brief summaries of their talks and explanations of their figures. In addition there are two appendices. One, contains detailed discussion of the shared mode of operation and the corresponding beam compatibility tables. The second appendix contains cost estimate details. An executive summary on budgets and schedules has been added, containing possible phased construction and outfitting scenarios and the corresponding expense and commitment profiles as well as new operational cost estimates. Material contained in the executive summary reflects the correction of some errors and new studies performed in response to the NASA Panel suggestions.

Pulse Duration of Seeded Free-Electron Lasers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Finetti, Paola; Hoppner, Hauke; Allaria, Enrico

The pulse duration, and, more generally, the temporal intensity profile of free-electron laser (FEL) pulses, is of utmost importance for exploring the new perspectives offered by FELs; it is a nontrivial experimental parameter that needs to be characterized. We measured the pulse shape of an extreme ultraviolet externally seeded FEL operating in high-gain harmonic generation mode. Two different methods based on the cross-correlation of the FEL pulses with an external optical laser were used. The two methods, one capable of single-shot performance, may both be implemented as online diagnostics in FEL facilities. The measurements were carried out at the seededmore » FEL facility FERMI. The FEL temporal pulse characteristics were measured and studied in a range of FEL wavelengths and machine settings, and they were compared to the predictions of a theoretical model. Finally, the measurements allowed a direct observation of the pulse lengthening and splitting at saturation, in agreement with the proposed theory.« less

Pulse Duration of Seeded Free-Electron Lasers

DOE PAGES

Finetti, Paola; Hoppner, Hauke; Allaria, Enrico; ...

2017-06-16

The pulse duration, and, more generally, the temporal intensity profile of free-electron laser (FEL) pulses, is of utmost importance for exploring the new perspectives offered by FELs; it is a nontrivial experimental parameter that needs to be characterized. We measured the pulse shape of an extreme ultraviolet externally seeded FEL operating in high-gain harmonic generation mode. Two different methods based on the cross-correlation of the FEL pulses with an external optical laser were used. The two methods, one capable of single-shot performance, may both be implemented as online diagnostics in FEL facilities. The measurements were carried out at the seededmore » FEL facility FERMI. The FEL temporal pulse characteristics were measured and studied in a range of FEL wavelengths and machine settings, and they were compared to the predictions of a theoretical model. Finally, the measurements allowed a direct observation of the pulse lengthening and splitting at saturation, in agreement with the proposed theory.« less

X-ray Free-electron Lasers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Feldhaus, J.; /DESY; Arthur, J.

In a free-electron laser (FEL) the lasing medium is a high-energy beam of electrons flying with relativistic speed through a periodic magnetic field. The interaction between the synchrotron radiation that is produced and the electrons in the beam induces a periodic bunching of the electrons, greatly increasing the intensity of radiation produced at a particular wavelength. Depending only on a phase match between the electron energy and the magnetic period, the wavelength of the FEL radiation can be continuously tuned within a wide spectral range. The FEL concept can be adapted to produce radiation wavelengths from millimeters to Angstroms, andmore » can in principle produce hard x-ray beams with unprecedented peak brightness, exceeding that of the brightest synchrotron source by ten orders of magnitude or more. This paper focuses on short-wavelength FELs. It reviews the physics and characteristic properties of single-pass FELs, as well as current technical developments aiming for fully coherent x-ray radiation pulses with pulse durations in the 100 fs to 100 as range. First experimental results at wavelengths around 100 nm and examples of scientific applications planned on the new, emerging x-ray FEL facilities are presented.« less

Nasreya: a treatment and disposal facility for industrial hazardous waste in Alexandria, Egypt: phase I.

PubMed

Ramadan, Adham R; Kock, Per; Nadim, Amani

2005-04-01

A facility for the treatment and disposal of industrial hazardous waste has been established in Alexandria, Egypt. Phase I of the facility encompassing a secure landfill and solar evaporation ponds is ready to receive waste, and Phase II encompassing physico-chemical treatment, solidification, and interim storage is underway. The facility, the Nasreya Centre, is the first of its kind in Egypt, and represents the nucleus for the integration, improvement and further expansion of different hazardous waste management practices and services in Alexandria. It has been developed within the overall legal framework of the Egyptian Law for the Environment, and is expected to improve prospects for enforcement of the regulatory requirements specified in this law. It has been developed with the overall aim of promoting the establishment of an integrated industrial hazardous waste management system in Alexandria, serving as a demonstration to be replicated elsewhere in Egypt. For Phase I, the Centre only accepts inorganic industrial wastes. In this respect, a waste acceptance policy has been developed, which is expected to be reviewed during Phase II, with an expansion of the waste types accepted.

Evaluation of Mercury in Liquid Waste Processing Facilities - Phase I Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jain, V.; Occhipinti, J.; Shah, H.

2015-07-01

This report provides a summary of Phase I activities conducted to support an Integrated Evaluation of Mercury in Liquid Waste System (LWS) Processing Facilities. Phase I activities included a review and assessment of the liquid waste inventory and chemical processing behavior of mercury using a system by system review methodology approach. Gaps in understanding mercury behavior as well as action items from the structured reviews are being tracked. 64% of the gaps and actions have been resolved.

Evaluation of mercury in liquid waste processing facilities - Phase I report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jain, V.; Occhipinti, J. E.; Shah, H.

2015-07-01

This report provides a summary of Phase I activities conducted to support an Integrated Evaluation of Mercury in Liquid Waste System (LWS) Processing Facilities. Phase I activities included a review and assessment of the liquid waste inventory and chemical processing behavior of mercury using a system by system review methodology approach. Gaps in understanding mercury behavior as well as action items from the structured reviews are being tracked. 64% of the gaps and actions have been resolved.

Theoretical study of the design and performance of a high-gain, high-extraction-efficiency FEL oscillator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Goldstein, J.; Nguyen, D.C.; Sheffield, R.L.

1996-10-01

We present the results of theoretical and simulation studies of the design and performance of a new F type of FEL oscillator. This device, known by the acronym RAFEL for Regenerative Amplifier Free-Electron Laser, will be constructed in the space presently occupied by the AFEL (Advanced FEL) at Los Alamos, and will be driven by an upgraded (to higher average power) version of the present AFEL linac. In order to achieve a long-time-averaged optical output power of {approximately} 1 kW using an electron beam with an average power of {approximately} 20 kW, a rather high extraction efficiency {eta} {approximately} 5%more » is required. We have designed a 2-m-long undulator to attain this goal: the first meter is untapered and provides high gain while the second meter is linearly-tapered in magnetic field amplitude to provide high extraction efficiency in the standard K-M-R manner. Two-plane focusing and linear polarization of the undulator are assumed. Electron-beam properties from PARMEIA simulations of the AFEL accelerator were used in the design. A large saturated gain, {approximately} 500, requires a very small optical feedback to keep the device operating at steady-state. However, the large gain leads to distorted optical modes which require two- and three-dimensional simulations to adequately treat diffraction effects. This FEL will be driven by 17 MeV electrons and will operate in the 16 {mu}m spectral region.« less

Advanced induction accelerator designs for ground based and space based FELs

NASA Astrophysics Data System (ADS)

Birx, Daniel

1994-04-01

The primary goal of this program was to improve the performance of induction accelerators with particular regards to their being used to drive Free Electron Lasers (FEL's). It is hoped that FEL's operating at visible wavelengths might someday be used to beam power from earth to extraterrestrial locations. One application of this technology might be strategic theater defense, but this power source might be used to propel vehicles or supplement solar energized systems. Our path toward achieving this goal was directed first toward optimization of the nonlinear magnetic material used in induction accelerator construction and secondly at the overall design in terms of cost, size and efficiency. We began this research effort with an in depth study into the properties of various nonlinear magnetic materials. With the data on nonlinear magnetic materials, so important to the optimization of efficiency, in hand, we envisioned a new induction accelerator design where all of the components were packaged together in one container. This induction accelerator module would combine an /ll-solid-state, nonlinear magnetic driver and the induction accelerator cells all in one convenient package. Each accelerator module (denoted SNOMAD-IVB) would produce 1.0 MeV of acceleration with the exception of the SNOMAD-IV injector module which would produce 0.5 MeV of acceleration for an electron beam current up to 1000 amperes.

Short-wavelength free-electron laser sources and science: a review.

PubMed

Seddon, E A; Clarke, J A; Dunning, D J; Masciovecchio, C; Milne, C J; Parmigiani, F; Rugg, D; Spence, J C H; Thompson, N R; Ueda, K; Vinko, S M; Wark, J S; Wurth, W

2017-11-01

This review is focused on free-electron lasers (FELs) in the hard to soft x-ray regime. The aim is to provide newcomers to the area with insights into: the basic physics of FELs, the qualities of the radiation they produce, the challenges of transmitting that radiation to end users and the diversity of current scientific applications. Initial consideration is given to FEL theory in order to provide the foundation for discussion of FEL output properties and the technical challenges of short-wavelength FELs. This is followed by an overview of existing x-ray FEL facilities, future facilities and FEL frontiers. To provide a context for information in the above sections, a detailed comparison of the photon pulse characteristics of FEL sources with those of other sources of high brightness x-rays is made. A brief summary of FEL beamline design and photon diagnostics then precedes an overview of FEL scientific applications. Recent highlights are covered in sections on structural biology, atomic and molecular physics, photochemistry, non-linear spectroscopy, shock physics, solid density plasmas. A short industrial perspective is also included to emphasise potential in this area.

Phase 0 study for a geothermal superheated water proof of concept facility

NASA Technical Reports Server (NTRS)

Douglass, R. H.; Pearson, R. O.

1974-01-01

A Phase 0 study for the selection of a representative liquid-dominated geothermal resource of moderate salinity and temperature is discussed. Selection and conceptual design of a nominal 10-MWe energy conversion system, and implementation planning for Phase 1: subsystem (component, experiments) and Phase 2: final design, construction, and operation of experimental research facilities are reported. The objective of the overall program is to demonstrate the technical and economic viability of utilizing moderate temperature and salinity liquid-dominated resources with acceptable environmental impact, and thus encourage commercial scale development of geothermal electrical power generation.

[Psychiatric residential care facilities in the Puglia region. Phase 1 results of the PROGRES project].

PubMed

Germinario, Cinzia; Semisa, Domenico; Picoco, Fulvio; Prato, Rosa; Lopalco, Pietro Luigi; Quarto, Michele

2004-01-01

One of the more important aspects of the psychiatric care reform in Italy has been the opening of a great number of psychiatric Non-Hospital Residential Facilities (NHRF). However, 22 years have elapsed since the reform and there are still very scarce data regarding such facilities, the type of patients being accomodated, and the types of treatments provided. The "PROGRES" (PROGetto RESidenze - Residential Project) project is the first national study regarding NHRFs ever carried out in Italy. The objectives of "PROGRES" are to make a survey of all NHRFs in Italy (Phase 1) and to perform a detailed assessment of 20% of the surveyed facilities and of the type of patients being treated (Phase 2). This paper reports the survey (Phase 1) results for the Puglia Region. As of March 31, 2003, 113 psychiatric residential facilities were present in Puglia, with a total of 1.479 beds. This results in an average of 13,08 beds per facility and a rate of 3,86 beds per 10.000 inhabitants. The number of NHRFs present in the territory of each Local Health Unit in Puglia is very variable. Most NHRFs (57%) opened after January 1997. Eighty-three percent have a 24-hour staff coverage while only 5,3% has a 2-hour staff coverage. Eighty five percent of the residential facilities are financed by the Italian National Healthcare System, while a small percentage is privately funded. In over half (69,93%) of the NHRFs the predominant patient age group is 40-59 years; 26,4% of the residential facilities accommodate patients below age 40 and only 3,53% accommodate patients over 60 years old.

Dog allergen (Can f 1) and cat allergen (Fel d 1) in US homes: Results from the National Survey of Lead and Allergens in Housing

PubMed Central

Arbes, Samuel J.; Cohn, Richard D.; Yin, Ming; Muilenberg, Michael L.; Friedman, Warren; Zeldin, Darryl C.

2017-01-01

Background Exposures to dog and cat allergens are believed to play important roles in the etiology of asthma; however, the levels of these allergens have never been assessed in a representative sample of US homes. Objective The objective of this study was to estimate and characterize exposures to Can f 1 (dog allergen) and Fel d 1 (cat allergen) in US homes. Methods Data were obtained from the National Survey of Lead and Allergens in Housing, a nationally representative survey of 831 US homes. Vacuumed-collected dust samples from the bed, bedroom floor, living room floor, and living room sofa were analyzed for concentrations of Can f 1 and Fel d 1 (micrograms of allergen per gram of dust). Results Although a dog or cat had lived in only 49.1% of homes in the previous 6 months, Can f 1 and Fel d 1 were detected in 100% and 99.9% of homes, respectively. Averaged over the sampled sites, geometric mean concentrations (µg/g) were 4.69 for Can f 1 and 4.73 for Fel d 1. Among homes with an indoor dog and cat, respectively, geometric mean concentrations were 69 for Can f 1 and 200 for Fel d 1. Among homes without the indoor pet, geometric mean concentrations were above 1.0. The independent predictors of elevated concentrations in homes without pets were all demographic variables that were also linked to a higher prevalence of pet ownership. Conclusions Can f 1 and Fel d 1 are universally present in US homes. Levels that have been associated with an increased risk of allergic sensitization were found even in homes without pets. Because of the transportability of these allergens on clothing, elevated levels in homes without pets, particularly among demographic groups in which pet ownership is more prevalent, implicate the community as an important source of these pet allergens. PMID:19055206

Free electron lasers driven by linear induction accelerators: High power radiation sources

NASA Technical Reports Server (NTRS)

Orzechowski, T. J.

1989-01-01

The technology of Free Electron Lasers (FELs) and linear induction accelerators (LIAs) is addressed by outlining the following topics: fundamentals of FELs; basic concepts of linear induction accelerators; the Electron Laser Facility (a microwave FEL); PALADIN (an infrared FEL); magnetic switching; IMP; and future directions (relativistic klystrons). This presentation is represented by viewgraphs only.

Microfocusing of the FERMI@Elettra FEL beam with a K-B active optics system: Spot size predictions by application of the WISE code

NASA Astrophysics Data System (ADS)

Raimondi, L.; Svetina, C.; Mahne, N.; Cocco, D.; Abrami, A.; De Marco, M.; Fava, C.; Gerusina, S.; Gobessi, R.; Capotondi, F.; Pedersoli, E.; Kiskinova, M.; De Ninno, G.; Zeitoun, P.; Dovillaire, G.; Lambert, G.; Boutu, W.; Merdji, H.; Gonzalez, A. I.; Gauthier, D.; Zangrando, M.

2013-05-01

FERMI@Elettra, the first seeded EUV-SXR free electron laser (FEL) facility located at Elettra Sincrotrone Trieste has been conceived to provide very short (10-100 fs) pulses with ultrahigh peak brightness and wavelengths from 100 nm to 4 nm. A section fully dedicated to the photon transport and analysis diagnostics, named PADReS, has already been installed and commissioned. Three of the beamlines, EIS-TIMEX, DiProI and LDM, installed after the PADReS section, are in advanced commissioning state and will accept the first users in December 2012. These beam lines employ active X-ray optics in order to focus the FEL beam as well as to perform a controlled beam-shaping at focus. Starting from mirror surface metrology characterization, it is difficult to predict the focal spot shape applying only methods based on geometrical optics such as the ray tracing. Within the geometrical optics approach one cannot take into account the diffraction effect from the optics edges, i.e. the aperture diffraction, and the impact of different surface spatial wavelengths to the spot size degradation. Both these effects are strongly dependent on the photon beam energy and mirror incident angles. We employed a method based on physical optics, which applies the Huygens-Fresnel principle to reflection (on which the WISE code is based). In this work we report the results of the first measurements of the focal spot in the DiProI beamline end-station and compare them to the predictions computed with Shadow code and WISE code, starting from the mirror surface profile characterization.

Reversible beam heater for suppression of microbunching instability by transverse gradient undulators

NASA Astrophysics Data System (ADS)

Liu, Tao; Qin, Weilun; Wang, Dong; Huang, Zhirong

2017-08-01

The microbunching instability driven by beam collective effects in a linear accelerator of a free-electron laser (FEL) facility significantly degrades the electron beam quality and FEL performance. A conventional method to suppress this instability is to introduce an additional uncorrelated energy spread by laser-electron interaction, which has been successfully operated in the Linac Coherent Light Source and Fermi@Elettra, etc. Some other ideas are recently proposed to suppress the instability without increasing energy spread, which could benefit the seeded FEL schemes. In this paper, we propose a reversible electron beam heater using two transverse gradient undulators to suppress the microbunching instability. This scheme introduces both an energy spread increase and a transverse-to-longitudinal phase space coupling, which suppress the microbunching instabilities driven by both longitudinal space charge and coherent synchrotron radiation before and within the system. Finally the induced energy spread increase and emittance growth are reversed. Theoretical analysis and numerical simulations are presented to verify the feasibility of the scheme and indicate the capability to improve the seeded FEL radiation performance.

Reversible beam heater for suppression of microbunching instability by transverse gradient undulators

DOE PAGES

Liu, Tao; Qin, Weilun; Wang, Dong; ...

2017-08-02

The microbunching instability driven by beam collective effects in a linear accelerator of a free-electron laser (FEL) facility significantly degrades the electron beam quality and FEL performance. A conventional method to suppress this instability is to introduce an additional uncorrelated energy spread by laser-electron interaction, which has been successfully operated in the Linac Coherent Light Source and Fermi@Elettra, etc. Some other ideas are recently proposed to suppress the instability without increasing energy spread, which could benefit the seeded FEL schemes. In this paper, we propose a reversible electron beam heater using two transverse gradient undulators to suppress the microbunching instability.more » This scheme introduces both an energy spread increase and a transverse-to-longitudinal phase space coupling, which suppress the microbunching instabilities driven by both longitudinal space charge and coherent synchrotron radiation before and within the system. Finally the induced energy spread increase and emittance growth are reversed. In conclusion, theoretical analysis and numerical simulations are presented to verify the feasibility of the scheme and indicate the capability to improve the seeded FEL radiation performance.« less

Spontaneous and amplified radiation at the initial stage of a SASE FEL.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Huang, Z.; Kim, K.-J.

At the initial stage of a self-amplified spontaneous emission (SASE) free-electron laser (FEL), spontaneous undulator radiation in certain experimental configurations can dominate the amplified signal over an extended undulator distance. In this paper they study both the spontaneous and the amplified radiation in the framework of the paraxial wave equation and determine the transition from the dominance of spontaneous emission to exponential amplification. They compare theoretical expectations with SASE simulation codes GINGER and GENESIS.

Discovering and annotating fish early life-stage (FELS) adverse outcome pathways: Putting the research strategy into practice

EPA Science Inventory

In May 2012, a HESI-sponsored expert workshop yielded a proposed research strategy for systematically discovering, characterizing, and annotating fish early life-stage (FELS) adverse outcome pathways (AOPs) as well as prioritizing AOP development in light of current restrictions ...

Performance of the 2 × 4-cell superconducting linac module for the THz-FEL facility

NASA Astrophysics Data System (ADS)

Kui, Zhou; Chenglong, Lao; Dai, Wu; Xing, Luo; Jianxin, Wang; Dexin, Xiao; Lijun, Shan; Tianhui, He; Xuming, Shen; Sifen, Lin; Linde, Yang; Hanbin, Wang; Xingfan, Yang; Ming, Li; Xiangyang, Lu

2018-07-01

A high average power THz radiation facility has been developed by the China Academy of Engineering Physics. It is the first CW THz user facility based on superconducting accelerator technology in China. The superconducting linac module, which contains two 4-cell 1.3 GHz TESLA-like superconducting radio frequency cavities, is a major component of this facility. The expected electron energy gain is 6-8 MeV with a field gradient of 8-10 MV/m. The design and fabrication of the linac module is complete. This paper discusses its assembly and results from cyromodule tests and beam commissioning. At 2 K, the cryomodule works smoothly and stably. Both cavities have achieved effective field gradients of 10 MV/m. In beam loading experiments, 8 MeV, 5 mA electron beams with an energy spread less than 0.2% have been produced, which satisfies our requirements.

Investigation of phase diagrams and physical stability of drug-polymer solid dispersions.

PubMed

Lu, Jiannan; Shah, Sejal; Jo, Seongbong; Majumdar, Soumyajit; Gryczke, Andreas; Kolter, Karl; Langley, Nigel; Repka, Michael A

2015-01-01

Solid dispersion technology has been widely explored to improve the solubility and bioavailability of poorly water-soluble compounds. One of the critical drawbacks associated with this technology is the lack of physical stability, i.e. the solid dispersion would undergo recrystallization or phase separation thus limiting a product's shelf life. In the current study, the melting point depression method was utilized to construct a complete phase diagram for felodipine (FEL)-Soluplus® (SOL) and ketoconazole (KTZ)-Soluplus® (SOL) binary systems, respectively, based on the Flory-Huggins theory. The miscibility or solubility of the two compounds in SOL was also determined. The Flory-Huggins interaction parameter χ values of both systems were calculated as positive at room temperature (25 °C), indicating either compound was miscible with SOL. In addition, the glass transition temperatures of both solid dispersion systems were theoretically predicted using three empirical equations and compared with the practical values. Furthermore, the FEL-SOL solid dispersions were subjected to accelerated stability studies for up to 3 months.

Fast Determination of the Element Excitation of an Active Phased Array Antenna

DTIC Science & Technology

1991-03-01

elementenexcitatie te, bepalen: de amplitude en fase van het elektrische ven-e veld moeten gemeten warden in slechts I richting in het verre veld van de ...Page 3 rapport no FEL-91-BO38 titel Een snelle bepaling van de excitatie van de elenienten van cen actieve phased array antenne auteur(s) I. J.G. van...van der Spek Onderzoek uItgevoerd door Ir. J.G. van Hezewijk SAMENVATIING (ONGERUBRICEERD) Het verre veld stralingsdiagram van een actieve phased array

A facility for gas- and condensed-phase measurements behind shock waves

NASA Astrophysics Data System (ADS)

Petersen, Eric L.; Rickard, Matthew J. A.; Crofton, Mark W.; Abbey, Erin D.; Traum, Matthew J.; Kalitan, Danielle M.

2005-09-01

A shock-tube facility consisting of two, single-pulse shock tubes for the study of fundamental processes related to gas-phase chemical kinetics and the formation and reaction of solid and liquid aerosols at elevated temperatures is described. Recent upgrades and additions include a new high-vacuum system, a new gas-handling system, a new control system and electronics, an optimized velocity-detection scheme, a computer-based data acquisition system, several optical diagnostics, and new techniques and procedures for handling experiments involving gas/powder mixtures. Test times on the order of 3 ms are possible with reflected-shock pressures up to 100 atm and temperatures greater than 4000 K. Applications for the shock-tube facility include the study of ignition delay times of fuel/oxidizer mixtures, the measurement of chemical kinetic reaction rates, the study of fundamental particle formation from the gas phase, and solid-particle vaporization, among others. The diagnostic techniques include standard differential laser absorption, FM laser absorption spectroscopy, laser extinction for particle volume fraction and size, temporally and spectrally resolved emission from gas-phase species, and a scanning mobility particle sizer for particle size distributions. Details on the set-up and operation of the shock tube and diagnostics are given, the results of a detailed uncertainty analysis on the accuracy of the test temperature inferred from the incident-shock velocity are provided, and some recent results are presented.

Endangered Languages and Literacy. Proceedings of the Fourth FEL Conference (Charlotte, North Carolina, September 21-24, 2000).

ERIC Educational Resources Information Center

Ostler, Nicholas, Ed.; Rudes, Blair, Ed.

Papers for the fourth Foundation for Endangered Languages (FEL) Conference include the following: "Endangered languages and Literacy" (Nicholas Ostler, Blair Rudes); "Keynote Address: On Native Language Literacy: a Personal Perspective" (Ofelia Zepeda); "A Community's Solution to Some Literacy Problems: The Mayangna of…

Feasibility study: Assess the feasibility of siting a monitored retrievable storage facility. Phase 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

King, J.W.

1993-08-01

The purpose of phase one of this study are: To understand the waste management system and a monitored retrievable storage facility; and to determine whether the applicant has real interest in pursuing the feasibility assessment process. Contents of this report are: Generating electric power; facts about exposure to radiation; handling storage, and transportation techniques; description of a proposed monitored retrievable storage facility; and benefits to be received by host jurisdiction.

Short-wavelength free-electron laser sources and science: a review

NASA Astrophysics Data System (ADS)

Seddon, E. A.; Clarke, J. A.; Dunning, D. J.; Masciovecchio, C.; Milne, C. J.; Parmigiani, F.; Rugg, D.; Spence, J. C. H.; Thompson, N. R.; Ueda, K.; Vinko, S. M.; Wark, J. S.; Wurth, W.

2017-11-01

This review is focused on free-electron lasers (FELs) in the hard to soft x-ray regime. The aim is to provide newcomers to the area with insights into: the basic physics of FELs, the qualities of the radiation they produce, the challenges of transmitting that radiation to end users and the diversity of current scientific applications. Initial consideration is given to FEL theory in order to provide the foundation for discussion of FEL output properties and the technical challenges of short-wavelength FELs. This is followed by an overview of existing x-ray FEL facilities, future facilities and FEL frontiers. To provide a context for information in the above sections, a detailed comparison of the photon pulse characteristics of FEL sources with those of other sources of high brightness x-rays is made. A brief summary of FEL beamline design and photon diagnostics then precedes an overview of FEL scientific applications. Recent highlights are covered in sections on structural biology, atomic and molecular physics, photochemistry, non-linear spectroscopy, shock physics, solid density plasmas. A short industrial perspective is also included to emphasise potential in this area. Dedicated to John M J Madey (1943-2016) and Rodolfo Bonifacio (1940-2016) whose perception, drive and perseverance paved the way for the realisation and development of short-wavelength free-electron lasers.

Low emittance lattice for the storage ring of the Turkish Light Source Facility TURKAY

NASA Astrophysics Data System (ADS)

Nergiz, Z.; Aksoy, A.

2015-06-01

The TAC (Turkish Accelerator Center) project aims to build an accelerator center in Turkey. The first stage of the project is to construct an Infra-Red Free Electron Laser (IR-FEL) facility. The second stage is to build a synchrotron radiation facility named TURKAY, which is a third generation synchrotron radiation light source that aims to achieve a high brilliance photon beam from a low emittance electron beam at 3 GeV. The electron beam parameters are highly dependent on the magnetic lattice of the storage ring. In this paper a low emittance storage ring for TURKAY is proposed and the beam dynamic properties of the magnetic lattice are investigated. Supported by Turkish Republic Ministry of Development (DPT2006K120470)

Blade and bladelet production at Hohle Fels Cave, AH IV in the Swabian Jura and its importance for characterizing the technological variability of the Aurignacian in Central Europe

PubMed Central

Conard, Nicholas J.

2018-01-01

Hohle Fels Cave in the Ach Valley of Southwestern Germany exhibits an Aurignacian sequence of 1 m thickness within geological horizons (GH) 6–8. The deposition of the layers took place during mild and cold phases between at least 42 ka (GI 10) and 36 ka calBP (GI 7). We present below a technological study of blade and bladelet production from AH IV (GH 7) at Hohle Fels. Our analyses show that blade manufacture is relatively constant, while bladelet production displays a high degree of variability in order to obtain different blanks. Knappers used a variety of burins as cores to produce fine bladelets. The results reveal a new variant of the Aurignacian in the Swabian Jura primarily characterized by the production of bladelets and microliths from burin-cores. The artefacts from the Swabian Aurignacian are technologically and functionally more diverse than earlier studies of the Geißenklösterle and Vogelherd sequences have suggested. The technological analyses presented here challenge the claim that the typo-chronological system from Southwestern Europe can be applied to the Central European Aurignacian. Instead, we emphasize the impact of technological and functional variables within the Aurignacian of the Swabian Jura. PMID:29630601

Concept of a staged FEL enabled by fast synchrotron radiation cooling of laser-plasma accelerated beam by solenoidal magnetic fields in plasma bubble

NASA Astrophysics Data System (ADS)

Seryi, Andrei; Lesz, Zsolt; Andreev, Alexander; Konoplev, Ivan

2017-03-01

A novel method for generating GigaGauss solenoidal fields in a laser-plasma bubble, using screw-shaped laser pulses, has been recently presented. Such magnetic fields enable fast synchrotron radiation cooling of the beam emittance of laser-plasma accelerated leptons. This recent finding opens a novel approach for design of laser-plasma FELs or colliders, where the acceleration stages are interleaved with laser-plasma emittance cooling stages. In this concept paper, we present an outline of what a staged plasma-acceleration FEL could look like, and discuss further studies needed to investigate the feasibility of the concept in detail.

The Low Density Matter (LDM) beamline at FERMI: optical layout and first commissioning.

PubMed

Svetina, Cristian; Grazioli, Cesare; Mahne, Nicola; Raimondi, Lorenzo; Fava, Claudio; Zangrando, Marco; Gerusina, Simone; Alagia, Michele; Avaldi, Lorenzo; Cautero, Giuseppe; de Simone, Monica; Devetta, Michele; Di Fraia, Michele; Drabbels, Marcel; Feyer, Vitaliy; Finetti, Paola; Katzy, Raphael; Kivimäki, Antti; Lyamayev, Viktor; Mazza, Tommaso; Moise, Angelica; Möller, Thomas; O'Keeffe, Patrick; Ovcharenko, Yevheniy; Piseri, Paolo; Plekan, Oksana; Prince, Kevin C; Sergo, Rudi; Stienkemeier, Frank; Stranges, Stefano; Coreno, Marcello; Callegari, Carlo

2015-05-01

The Low Density Matter (LDM) beamline has been built as part of the FERMI free-electron laser (FEL) facility to serve the atomic, molecular and cluster physics community. After the commissioning phase, it received the first external users at the end of 2012. The design and characterization of the LDM photon transport system is described, detailing the optical components of the beamline.

Pulse-resolved intensity measurements at a hard X-ray FEL using semi-transparent diamond detectors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Roth, Thomas; Freund, Wolfgang; Boesenberg, Ulrike

Solid-state ionization chambers are presented based on thin diamond crystals that allow pulse-resolved intensity measurements at a hard X-ray free-electron laser (FEL), up to the 4.5 MHz repetition rate that will become available at the European XFEL. Due to the small X-ray absorption of diamond the thin detectors are semi-transparent which eases their use as non-invasive monitoring devices in the beam. FELs are characterized by strong pulse-to-pulse intensity fluctuations due to the self-amplified spontaneous emission (SASE) process and in many experiments it is mandatory to monitor the intensity of each individual pulse. Two diamond detectors with different electrode materials, berylliummore » and graphite, were tested as intensity monitors at the XCS endstation of the Linac Coherent Light Source (LCLS) using the pink SASE beam at 9 keV. The performance is compared with LCLS standard monitors that detect X-rays backscattered from thin SiN foils placed in the beam. In conclusion, the graphite detector can also be used as a beam position monitor although with rather coarse resolution.« less

Imaging cervical cytology with scanning near-field optical microscopy (SNOM) coupled with an IR-FEL.

PubMed

Halliwell, Diane E; Morais, Camilo L M; Lima, Kássio M G; Trevisan, Julio; Siggel-King, Michele R F; Craig, Tim; Ingham, James; Martin, David S; Heys, Kelly A; Kyrgiou, Maria; Mitra, Anita; Paraskevaidis, Evangelos; Theophilou, Georgios; Martin-Hirsch, Pierre L; Cricenti, Antonio; Luce, Marco; Weightman, Peter; Martin, Francis L

2016-07-12

Cervical cancer remains a major cause of morbidity and mortality among women, especially in the developing world. Increased synthesis of proteins, lipids and nucleic acids is a pre-condition for the rapid proliferation of cancer cells. We show that scanning near-field optical microscopy, in combination with an infrared free electron laser (SNOM-IR-FEL), is able to distinguish between normal and squamous low-grade and high-grade dyskaryosis, and between normal and mixed squamous/glandular pre-invasive and adenocarcinoma cervical lesions, at designated wavelengths associated with DNA, Amide I/II and lipids. These findings evidence the promise of the SNOM-IR-FEL technique in obtaining chemical information relevant to the detection of cervical cell abnormalities and cancer diagnosis at spatial resolutions below the diffraction limit (≥0.2 μm). We compare these results with analyses following attenuated total reflection Fourier-transform infrared (ATR-FTIR) spectroscopy; although this latter approach has been demonstrated to detect underlying cervical atypia missed by conventional cytology, it is limited by a spatial resolution of ~3 μm to 30 μm due to the optical diffraction limit.

Imaging cervical cytology with scanning near-field optical microscopy (SNOM) coupled with an IR-FEL

PubMed Central

Halliwell, Diane E.; Morais, Camilo L. M.; Lima, Kássio M. G.; Trevisan, Julio; Siggel-King, Michele R. F.; Craig, Tim; Ingham, James; Martin, David S.; Heys, Kelly A.; Kyrgiou, Maria; Mitra, Anita; Paraskevaidis, Evangelos; Theophilou, Georgios; Martin-Hirsch, Pierre L.; Cricenti, Antonio; Luce, Marco; Weightman, Peter; Martin, Francis L.

2016-01-01

Cervical cancer remains a major cause of morbidity and mortality among women, especially in the developing world. Increased synthesis of proteins, lipids and nucleic acids is a pre-condition for the rapid proliferation of cancer cells. We show that scanning near-field optical microscopy, in combination with an infrared free electron laser (SNOM-IR-FEL), is able to distinguish between normal and squamous low-grade and high-grade dyskaryosis, and between normal and mixed squamous/glandular pre-invasive and adenocarcinoma cervical lesions, at designated wavelengths associated with DNA, Amide I/II and lipids. These findings evidence the promise of the SNOM-IR-FEL technique in obtaining chemical information relevant to the detection of cervical cell abnormalities and cancer diagnosis at spatial resolutions below the diffraction limit (≥0.2 μm). We compare these results with analyses following attenuated total reflection Fourier-transform infrared (ATR-FTIR) spectroscopy; although this latter approach has been demonstrated to detect underlying cervical atypia missed by conventional cytology, it is limited by a spatial resolution of ~3 μm to 30 μm due to the optical diffraction limit. PMID:27406404

Pulse-resolved intensity measurements at a hard X-ray FEL using semi-transparent diamond detectors

DOE PAGES

Roth, Thomas; Freund, Wolfgang; Boesenberg, Ulrike; ...

2018-01-01

Solid-state ionization chambers are presented based on thin diamond crystals that allow pulse-resolved intensity measurements at a hard X-ray free-electron laser (FEL), up to the 4.5 MHz repetition rate that will become available at the European XFEL. Due to the small X-ray absorption of diamond the thin detectors are semi-transparent which eases their use as non-invasive monitoring devices in the beam. FELs are characterized by strong pulse-to-pulse intensity fluctuations due to the self-amplified spontaneous emission (SASE) process and in many experiments it is mandatory to monitor the intensity of each individual pulse. Two diamond detectors with different electrode materials, berylliummore » and graphite, were tested as intensity monitors at the XCS endstation of the Linac Coherent Light Source (LCLS) using the pink SASE beam at 9 keV. The performance is compared with LCLS standard monitors that detect X-rays backscattered from thin SiN foils placed in the beam. In conclusion, the graphite detector can also be used as a beam position monitor although with rather coarse resolution.« less

Feasibility of MHD submarine propulsion. Phase II, MHD propulsion: Testing in a two Tesla test facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Doss, E.D.; Sikes, W.C.

1992-09-01

This report describes the work performed during Phase 1 and Phase 2 of the collaborative research program established between Argonne National Laboratory (ANL) and Newport News Shipbuilding and Dry Dock Company (NNS). Phase I of the program focused on the development of computer models for Magnetohydrodynamic (MHD) propulsion. Phase 2 focused on the experimental validation of the thruster performance models and the identification, through testing, of any phenomena which may impact the attractiveness of this propulsion system for shipboard applications. The report discusses in detail the work performed in Phase 2 of the program. In Phase 2, a two Teslamore » test facility was designed, built, and operated. The facility test loop, its components, and their design are presented. The test matrix and its rationale are discussed. Representative experimental results of the test program are presented, and are compared to computer model predictions. In general, the results of the tests and their comparison with the predictions indicate that thephenomena affecting the performance of MHD seawater thrusters are well understood and can be accurately predicted with the developed thruster computer models.« less

Endangered Languages and the Media. Proceedings of the Fifth FEL Conference (Agadir, Morocco, September 20-23, 2001).

ERIC Educational Resources Information Center

Moseley, Christopher, Ed.; Ostler, Nicholas, Ed.; Ouzzate, Hassan, Ed.

Papers for the fifth Foundation for Endangered Languages (FEL) Conference include the following papers: "The State and the Global Marketplace in the Provision of Minority Media Services" (George Jones); "Local Language Media: What Does It Take?" (Paul Lewis); "Power of the Media for the Good of Small Languages: An Indian…

Transformations of Gaussian Light Beams Caused by Reflection in FEL (free Electron Lasers) Resonators

DTIC Science & Technology

1988-10-27

il FILE COPy Naval Research Laboratory Washingon, DC 20375-500 NRL Memorandum Report 6347 ,qJ. o Transformations of Gaussian Light Beams N Caused by...Transformations of 7aussian Light Beams Caused by Reflection in FEL Resonators 12 PERSONAL AUTHOR(S) Riyopoulos,* S., Tang, C.M. and Sprangle, P...34 𔃾-6603 -"I, -,’ SECURITY CLASSIFICATION OF THIS PAGE 19. ABSTRACTS (Continued) cross-coupling among vector components of the radiation field, caused

Quantitative genetic analysis of cellular adhesion molecules: the Fels Longitudinal Study.

PubMed

Lee, Miryoung; Czerwinski, Stefan A; Choh, Audrey C; Demerath, Ellen W; Sun, Shumei S; Chumlea, Wm C; Towne, Bradford; Siervogel, Roger M

2006-03-01

Circulating concentrations of inflammatory markers predict cardiovascular disease (CVD) risk and are closely associated with obesity. However, little is known concerning genetic influences on serum levels of inflammatory markers. In this study, we estimated the heritability (h2) of soluble cellular adhesion molecule (sCAM) concentrations and examined the correlational architecture between different sCAMs. The study population included 234 men and 270 women aged 18-76 years, belonging to 121 families participating in the Fels Longitudinal Study. Serum levels of soluble intercellular adhesion molecule-1 (sICAM-1), vascular cell adhesion molecule-1 (sVCAM-1), E-selectin (sESEL-1) and P-selectin (sPSEL-1) were assayed using commercially available kits. A variance components-based maximum likelihood method was used to estimate the h2 of the different serum inflammatory markers while simultaneously adjusting for the effects of known CVD risk factors, such as age and smoking. Additionally, we used bivariate extensions of these methods to estimate genetic and random environmental correlations among sCAMs. Levels of sCAMs were significantly heritable: h2=0.24+/-0.10 for sICAM-1, h2=0.22+/-0.10 for sVCAM-1, h2=0.50+/-0.11 for sESEL-1, and h2=0.46+/-0.10 for sPSEL-1. In addition, a significant genetic correlation (rho(G)=0.63) was found between sICAM-1 and sVCAM-1 indicating some degree of shared genetic control. In the Fels Longitudinal Study, the levels of four sCAMs are significantly influenced by genetic effects, and sICAM-1 shares a common genetic background with sVCAM-1.

Phase II Investigation at the Former CCC/USDA Grain Storage Facility in Savannah, Missouri

DOE Office of Scientific and Technical Information (OSTI.GOV)

LaFreniere, Lorraine M.

contamination potentially associated with a number of former CCC/USDA grain storage facilities in Missouri. The site characterization at Savannah is being conducted on behalf of the CCC/USDA by the Environmental Science Division of Argonne National Laboratory. The investigation is being conducted in phases, so that information obtained and interpretations developed during each incremental stage can be used most effectively to guide subsequent phases of the program. Phase II objectives: Investigate the more detailed characteristics of groundwater flow in the vicinity of the former CCC/USDA facility and the contaminated Morgan and MoDOT private wells; Obtain additional information on the vertical and lateral distribution and concentrations of carbon tetrachloride in groundwater in the vicinity of the former CCC/USDA facility and the contaminated Morgan and MoDOT private wells; Investigate further for possible evidence of carbon tetrachloride in the subsurface (vadose zone) and deeper soils beneath the former CCC/USDA facility, as well as in the vicinity of the contaminated MoDOT private well.« less

Design and test of SX-FEL cavity BPM

NASA Astrophysics Data System (ADS)

Yuan, Ren-Xian; Zhou, Wei-Min; Chen, Zhi-Chu; Yu, Lu-Yang; Wang, Bao-Pen; Leng, Yong-Bin

2013-11-01

This paper reports the design and cold test of the cavity beam position monitor (CBPM) for SX-FEL to fulfill the requirement of beam position measurement resolution of less than 1 μm, even 0.1 μm. The CBPM was optimized by using a coupling slot to damp the TM010 mode in the output signal. The isolation of TM010 mode is about 117 dB, and the shunt impedance is about 200 Ω@4.65 GHz with the quality factor 80 from MAFIA simulation and test result. A special antenna was designed to load power for reducing excitation of other modes in the cavity. The resulting output power of TM110 mode was about 90 mV/mm when the source was 6 dBm, and the accomplishable minimum voltage was about 200 μV. The resolution of the CBPM was about 0.1 μm from the linear fitting result based on the cold test.

Nonlinear optics with coherent free electron lasers

NASA Astrophysics Data System (ADS)

Bencivenga, F.; Capotondi, F.; Mincigrucci, R.; Cucini, R.; Manfredda, M.; Pedersoli, E.; Principi, E.; Simoncig, A.; Masciovecchio, C.

2016-12-01

We interpreted the recent construction of free electron laser (FELs) facilities worldwide as an unprecedented opportunity to bring concepts and methods from the scientific community working with optical lasers into the domain of x-ray science. This motivated our efforts towards the realization of FEL-based wave-mixing applications. In this article we present new extreme ultraviolet transient grating (X-TG) data from vitreous SiO2, collected using two crossed FEL pulses (photon frequency 38 eV) to generate the X-TG and a phase matched optical probing pulse (photon frequency 3.1 eV). This experiment extends our previous investigation, which was carried out on a nominally identical sample using a different FEL photon frequency (45 eV) to excite the X-TG. The present data are featured by a peak intensity of the X-TG signal substantially larger than that previously reported and by slower modulations of the X-TG signal at positive delays. These differences could be ascribed to the different FEL photon energy used in the two experiments or to differences in the sample properties. A systematic X-TG study on the same sample as a function of the FEL wavelength is needed to draw a consistent conclusion. We also discuss how the advances in the performance of the FELs, in terms of generation of fully coherent photon pulses and multi-color FEL emission, may push the development of original experimental strategies to study matter at the femtosecond-nanometer time-length scales, with the unique option of element and chemical state specificity. This would allow the development of advanced experimental tools based on wave-mixing processes, which may have a tremendous impact in the study of a large array of phenomena, ranging from nano-dynamics in complex materials to charge and energy transfer processes.

The Linac Coherent Light Source

DOE PAGES

White, William E.; Robert, Aymeric; Dunne, Mike

2015-05-01

The Linac Coherent Light Source (LCLS) at the SLAC National Accelerator Laboratory was the first hard X-ray free-electron laser (FEL) to operate as a user facility. After five years of operation, LCLS is now a mature FEL user facility. Our personal views about opportunities and challenges inherent to these unique light sources are discussed.

Porting of EPICS to Real Time UNIX, and Usage Ported EPICS for FEL Automation

NASA Astrophysics Data System (ADS)

Salikova, Tatiana

This article describes concepts and mechanisms used in porting of EPICS (Experimental Physical and Industrial Control System) codes to platform of operating system UNIX. Without destruction of EPICS architecture, new features of EPICS provides the support for real time operating system LynxOS/x86 and equipment produced by INP (Budker Institute of Nuclear Physics). Application of ported EPICS reduces the cost of software and hardware is used for automation of FEL (Free Electron Laser) complex.

The Low Density Matter (LDM) beamline at FERMI: optical layout and first commissioning

PubMed Central

Svetina, Cristian; Grazioli, Cesare; Mahne, Nicola; Raimondi, Lorenzo; Fava, Claudio; Zangrando, Marco; Gerusina, Simone; Alagia, Michele; Avaldi, Lorenzo; Cautero, Giuseppe; de Simone, Monica; Devetta, Michele; Di Fraia, Michele; Drabbels, Marcel; Feyer, Vitaliy; Finetti, Paola; Katzy, Raphael; Kivimäki, Antti; Lyamayev, Viktor; Mazza, Tommaso; Moise, Angelica; Möller, Thomas; O’Keeffe, Patrick; Ovcharenko, Yevheniy; Piseri, Paolo; Plekan, Oksana; Prince, Kevin C.; Sergo, Rudi; Stienkemeier, Frank; Stranges, Stefano; Coreno, Marcello; Callegari, Carlo

2015-01-01

The Low Density Matter (LDM) beamline has been built as part of the FERMI free-electron laser (FEL) facility to serve the atomic, molecular and cluster physics community. After the commissioning phase, it received the first external users at the end of 2012. The design and characterization of the LDM photon transport system is described, detailing the optical components of the beamline. PMID:25931066

A facile way to control phase of tin selenide flakes by chemical vapor deposition

NASA Astrophysics Data System (ADS)

Wang, Zhigang; Pang, Fei

2018-06-01

Although two-dimensional (2D) tin selenides are attracting intense attentions, studies on its phase transition are still relatively few. Here we report a facile way to control the phase growth of tin selenide flakes on mica and SiO2/Si by only adjusting nominal Sn:Se ratio, which refers to the amount of loaded SnO2 and Se precursors. High normal Sn:Se ratio induced SnSe flakes, conversely SnSe2 flakes formed. It could be used as a practical guide to selectively synthesize pure phase of single crystalline 2D layered chalcogenide materials similar to tin selenides.

A concept for Z-dependent microbunching measurements with coherent X-ray transition radiation in a sase FEL

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lumpkin, A.H.; Fawley, W.M.; Rule, D.W.

We present an adaptation of the measurements performed in the visible-to-VUV regime of the z-dependent microbunching in a self-amplified spontaneous emission (SASE) free-electron laser (FEL). In these experiments a thin metal foil was used to block the more intense SASE radiation and to generate coherent optical transition radiation (COTR) as one source in a two-foil interferometer. However, for the proposed x-ray SASE FELs, the intense SASE emission is either too strongly transmitted at 1.5 Angstrom or the needed foil thickness for blocking scatters the electron beam too much. Since x-ray transition radiation (XTR) is emitted in an annulus with openingmore » angle 1/g = 36 mrad for 14.09-GeV electrons, we propose using a thin foil or foil stack to generate the XTR and coherent XTR (CXTR) and an annular crystal to wavelength sort the radiation. The combined selectivity in angle and wavelength will favor the CXTR over SASE by about eight orders of magnitude. Time-dependent GINGER simulations support the z-dependent gain evaluation plan.« less

Conceptual design of two-phase fluid mechanics and heat transfer facility for spacelab

NASA Technical Reports Server (NTRS)

North, B. F.; Hill, M. E.

1980-01-01

Five specific experiments were analyzed to provide definition of experiments designed to evaluate two phase fluid behavior in low gravity. The conceptual design represents a fluid mechanics and heat transfer facility for a double rack in Spacelab. The five experiments are two phase flow patterns and pressure drop, flow boiling, liquid reorientation, and interface bubble dynamics. Hardware was sized, instrumentation and data recording requirements defined, and the five experiments were installed as an integrated experimental package. Applicable available hardware was selected in the experiment design and total experiment program costs were defined.

A fast analytical undulator model for realistic high-energy FEL simulations

NASA Astrophysics Data System (ADS)

Tatchyn, R.; Cremer, T.

1997-02-01

A number of leading FEL simulation codes used for modeling gain in the ultralong undulators required for SASE saturation in the <100 Å range employ simplified analytical models both for field and error representations. Although it is recognized that both the practical and theoretical validity of such codes could be enhanced by incorporating realistic undulator field calculations, the computational cost of doing this can be prohibitive, especially for point-to-point integration of the equations of motion through each undulator period. In this paper we describe a simple analytical model suitable for modeling realistic permanent magnet (PM), hybrid/PM, and non-PM undulator structures, and discuss selected techniques for minimizing computation time.

Free-electron laser wavelength-selective materials alteration and photoexcitation spectroscopy

NASA Astrophysics Data System (ADS)

Tolk, N. H.; Albridge, R. G.; Barnes, A. V.; Barnes, B. M.; Davidson, J. L.; Gordon, V. D.; Margaritondo, G.; McKinley, J. T.; Mensing, G. A.; Sturmann, J.

1996-10-01

The free-electron laser (FEL) has become an important tool for producing high-intensity photon beams, especially in the infrared. Synchrotron radiation's primary spectral domains are in the ultraviolet and X-ray region. FEL's are therefore excellent complimentary facilities to synchrotron radiation sources. While FEL's have seen only limited use in experimentation, recently developed programs at Vanderbilt University in Nashville, TN, are swiftly rectifying this situation. This review paper examines practical experience obtained through pioneering programs using the Vanderbilt FEL, which currently hosts one of the largest FEL materials research programs. Results will be discussed in three areas: two-photon absorption in germanium, FEL-assisted internal photoemission measurements of interface energy barriers (FELIPE), and wavelength-specific laser diamond ablation.

Systematic design and three-dimensional simulation of X-ray FEL oscillator for Shanghai Coherent Light Facility

NASA Astrophysics Data System (ADS)

Li, Kai; Deng, Haixiao

2018-07-01

The Shanghai Coherent Light Facility (SCLF) is a quasi-continuous wave hard X-ray free electron laser facility, which is currently under construction. Due to the high repetition rate and high-quality electron beams, it is straightforward to consider X-ray free electron laser oscillator (XFELO) operation for the SCLF. In this paper, the main processes for XFELO design, and parameter optimization of the undulator, X-ray cavity, and electron beam are described. A three-dimensional X-ray crystal Bragg diffraction code, named BRIGHT, was introduced for the first time, which can be combined with the GENESIS and OPC codes for the numerical simulations of the XFELO. The performance of the XFELO of the SCLF is investigated and optimized by theoretical analysis and numerical simulation.

Final report : phase I investigation at the former CCC/USDA grain storage facility in Savannah, Missouri.

DOE Office of Scientific and Technical Information (OSTI.GOV)

LaFreniere, L. M.; Environmental Science Division

Service Agency of the USDA and the MoDNR, to address carbon tetrachloride contamination potentially associated with a number of former CCC/USDA grain storage facilities in Missouri. The site characterization at Savannah is being conducted on behalf of the CCC/USDA by the Environmental Science Division of Argonne National Laboratory. A phased approach is being employed by the CCC/USDA and Argonne, with the approval of the MoDNR, so that information obtained and interpretations developed during each incremental stage of the study can be used most effectively to guide subsequent aspects of the program. This report presents the technical findings of Phase I of Argonne's studies. The Phase I investigation was undertaken in accord with the final site-specific Phase I Work Plan for Savannah (Argonne 2007), as well as with the Master Work Plan (MWPK) for CCC/USDAArgonne operations in the state of Kansas (Argonne 2002), which the MoDNR reviewed and approved (with minor revisions) for temporary use in Missouri to facilitate the start-up of the CCC/USDA's activities at Savannah. (Argonne is developing a similar Master Work Plan for operations in Missouri that is based on the existing MWPK, with the approval of the MoDNR. The Missouri document has not been finalized, however, at this time.) The site-specific Savannah Work Plan (Argonne 2007; approved by the MoDNR [2007a]) (1) summarized the pre-existing knowledge base for the Savannah investigation site compiled by Argonne and (2) described the site-specific technical objectives and the intended scope of work developed for this phase of the investigation. Four primary technical objectives were identified for the Phase I studies, as follows: (1) Update the previous (MoDNR 2000a,b) inventory and status of private wells in the immediate vicinity of the former CCC/USDA grain storage facility, and sample the identified wells for analyses for volatile organic compounds (VOCs) and geochemical constituents. (2) Investigate for possible

Observations of z-dependent microbunching harmonic intensities using COTR in a SASE FEL.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lumpkin, A. H.; Biedron, S. G.; Dejus, R. J.

The nonlinear generation of harmonics in a self-amplified spontaneous emission (SASE) free-electron laser (FEL) continues to be of interest. Complementary to such studies is the search for information on the electron beam microbunching harmonic components, which are revealed by coherent optical transition radiation (COTR) experiments. An initial z-dependent set of data has been obtained with the fundamental at 530 nm and the second harmonic at 265 nm. The latter data were collected after every other undulator in a nine-undulator string. These results are compared to estimates based on GINGER and an analytical model for nonlinear harmonic generation.

Identification of an immunodominant region of Fel d 1 and characterization of constituent epitopes.

PubMed

Bateman, E A L; Ardern-Jones, M R; Ogg, G S

2008-11-01

Characterization of T cell epitopes restricted by common HLA alleles is a powerful tool in the understanding of the immune responses to allergens and for the identification of potential peptides for future peptide immunotherapy (PIT). One important requirement is the identification and use of peptides that will bind to HLA molecules covering a large proportion of the population. To identify commonly recognized CD4(+) T cell epitopes in Fel d 1, restricted through frequently expressed HLA molecules for potential future use in PIT. HLA matched antigen presenting cells, HLA blocking antibodies, and peptide truncations were used in ELISpot assays to establish HLA-restricted T cell epitopes. Cytokine responses were measured by ex vivo and cultured IFN-gamma, IL-4, and IL-10 ELISpots. Responses to an immunodominant region of chain 2 were identified in the majority of atopic individuals and epitopes restricted by HLA-DQB1(*)06 and -DPB1(*)0401 were characterized in detail. Significantly higher ex vivo IL-4 and lower IFN-gamma responses were observed to both epitopes in individuals with atopic dermatitis (AD) compared with those without disease. IL-10 responses were significantly lower in those with AD in the individuals with HLA-DPB1(*)0401. We have identified an immunodominant region of Fel d 1 which is frequently recognized by CD4(+) T cells from atopic individuals and contains epitopes that are restricted by very common HLA alleles.

Time-diagnostics for improved dynamics experiments at XUV FELs

NASA Astrophysics Data System (ADS)

Drescher, Markus; Frühling, Ulrike; Krikunova, Maria; Maltezopoulos, Theophilos; Wieland, Marek

2010-10-01

Significantly structured and fluctuating temporal profiles of pulses from self-amplified spontaneous emission free electron lasers as well as their unstable timing require time diagnostics on a single-shot basis. The duration and structure of extreme-ultraviolet (XUV) pulses from the Free Electron Laser (FEL) in Hamburg (FLASH) are becoming accessible using a variation of the streak camera principle, where photoemitted electrons are energetically streaked in the electric field component of a terahertz electromagnetic wave. The timing with respect to an independently generated laser pulse can be measured in an XUV/laser cross-correlator, based on a non-collinear superposition of both pulses on a solid state surface and detection of XUV-induced modulations of its reflectivity for visible light. Sorting of data according to the measured timing dramatically improves the temporal resolution of an experiment sampling the relaxation of transient electronic states in xenon after linear- as well as nonlinear excitation with intense XUV pulses from FLASH.

Generation and characterization of ultra-short electron beams for single spike infrared FEL radiation at SPARC_LAB

NASA Astrophysics Data System (ADS)

Villa, F.; Anania, M. P.; Artioli, M.; Bacci, A.; Bellaveglia, M.; Bisesto, F. G.; Biagioni, A.; Carpanese, M.; Cardelli, F.; Castorina, G.; Chiadroni, E.; Cianchi, A.; Ciocci, F.; Croia, M.; Curcio, A.; Dattoli, G.; Gallo, A.; Di Giovenale, D.; Di Palma, E.; Di Pirro, G.; Ferrario, M.; Filippi, F.; Giannessi, L.; Giribono, A.; Marocchino, A.; Massimo, F.; Mostacci, A.; Petralia, A.; Petrarca, M.; Petrillo, V.; Piersanti, L.; Pioli, S.; Pompili, R.; Romeo, S.; Rossi, A. R.; Scifo, J.; Shpakov, V.; Vaccarezza, C.

2017-09-01

The technique for producing and measuring few tens of femtosecond electron beams, and the consequent generation of few tens femtoseconds single spike FEL radiation pulses at SPARC_LAB is presented. The undulator has been used in the double role of radiation source and diagnostic tool for the characterization of the electron beam. The connection between the electron bunch length and the radiation bandwidth is analyzed.

The future SwissFEL facility - challenges from a radiation protection point of view

NASA Astrophysics Data System (ADS)

Strabel, Claudia; Fuchs, Albert; Galev, Roman; Hohmann, Eike; Lüscher, Roland; Musto, Elisa; Mayer, Sabine

2017-09-01

The Swiss Free Electron Laser is a new large-scale facility currently under construction at the Paul Scherrer Institute. Accessible areas surrounding the 720 m long accelerator tunnel, together with the pulsed time structure of the primary beam, lead to new challenges for ensuring that the radiation level in these areas remains in compliance with the legal constraints. For this purpose an online survey system based on the monitoring of the ambient dose rate arising from neutrons inside of the accelerator tunnel and opportunely calibrated to indicate the total dose rate outside of the tunnel, will be installed. The presented study provides a conceptual overview of this system, its underlying assumptions and measurements so far performed to validate its concept.

Coatings for FEL optics: preparation and characterization of B4C and Pt

PubMed Central

Störmer, Michael; Siewert, Frank; Horstmann, Christian; Buchheim, Jana; Gwalt, Grzegorz

2018-01-01

Large X-ray mirrors are required for beam transport at both present-day and future free-electron lasers (FELs) and synchrotron sources worldwide. The demand for large mirrors with lengths up to 1 m single layers consisting of light or heavy elements has increased during the last few decades. Accordingly, surface finishing technology is now able to produce large substrate lengths with micro-roughness on the sub-nanometer scale. At the Helmholtz-Zentrum Geesthacht (HZG), a 4.5 m-long sputtering facility enables us to deposit a desired single-layer material some tens of nanometers thick. For the European XFEL project, the shape error should be less than 2 nm over the whole 1 m X-ray mirror length to ensure the safe and efficient delivery of X-ray beams to the scientific instruments. The challenge is to achieve thin-film deposition on silicon substrates, benders and gratings without any change in mirror shape. Thin films of boron carbide and platinum with a thickness in the range 30–100 nm were manufactured using the HZG sputtering facility. This setup is able to cover areas of up to 1500 mm × 120 mm in one step using rectangular sputtering sources. The coatings produced were characterized using various thin-film methods. It was possible to improve the coating process to achieve a very high uniformity of the layer thickness. The movement of the substrate in front of the sputtering source has been optimized. A variation in B4C layer thickness below 1 nm (peak-to-valley) was achieved at a mean thickness of 51.8 nm over a deposition length of 1.5 m. In the case of Pt, reflectometry and micro-roughness measurements were performed. The uniformity in layer thickness was about 1 nm (peak-to-valley). The micro-roughness of the Pt layers showed no significant change in the coated state for layer thicknesses of 32 nm and 102 nm compared with the uncoated substrate state. The experimental results achieved will be discussed with regard to current

Coatings for FEL optics: preparation and characterization of B4C and Pt.

PubMed

Störmer, Michael; Siewert, Frank; Horstmann, Christian; Buchheim, Jana; Gwalt, Grzegorz

2018-01-01

Large X-ray mirrors are required for beam transport at both present-day and future free-electron lasers (FELs) and synchrotron sources worldwide. The demand for large mirrors with lengths up to 1 m single layers consisting of light or heavy elements has increased during the last few decades. Accordingly, surface finishing technology is now able to produce large substrate lengths with micro-roughness on the sub-nanometer scale. At the Helmholtz-Zentrum Geesthacht (HZG), a 4.5 m-long sputtering facility enables us to deposit a desired single-layer material some tens of nanometers thick. For the European XFEL project, the shape error should be less than 2 nm over the whole 1 m X-ray mirror length to ensure the safe and efficient delivery of X-ray beams to the scientific instruments. The challenge is to achieve thin-film deposition on silicon substrates, benders and gratings without any change in mirror shape. Thin films of boron carbide and platinum with a thickness in the range 30-100 nm were manufactured using the HZG sputtering facility. This setup is able to cover areas of up to 1500 mm × 120 mm in one step using rectangular sputtering sources. The coatings produced were characterized using various thin-film methods. It was possible to improve the coating process to achieve a very high uniformity of the layer thickness. The movement of the substrate in front of the sputtering source has been optimized. A variation in B 4 C layer thickness below 1 nm (peak-to-valley) was achieved at a mean thickness of 51.8 nm over a deposition length of 1.5 m. In the case of Pt, reflectometry and micro-roughness measurements were performed. The uniformity in layer thickness was about 1 nm (peak-to-valley). The micro-roughness of the Pt layers showed no significant change in the coated state for layer thicknesses of 32 nm and 102 nm compared with the uncoated substrate state. The experimental results achieved will be discussed with regard to current

Laser-plasma interactions from thin tapes for high-energy electron accelerators and seeding compact FELs

NASA Astrophysics Data System (ADS)

Shaw, Brian Henry

This thesis comprises a detailed investigation of the physics of using a plasma mirror (PM) from a tape by reflecting ultrashort pulses from a laser-triggered surface plasma. The tapes used in the characterization of the PM are VHS and computer data storage tape. The tapes are 6.6 m (computer storage tape) and 15 m (VHS) thick. Each tape is 0.5 inches wide, and 10s of meters of tape are spooled using a tape drive; providing thousands of shots on a single reel of tape. The amount of reflected energy of the PM was studied for different input intensities. The fluence was varied by translating the focus of the laser upstream and downstream of the tape, which changed the spot size on the tape surface and hence changed the fluence. This study measured reflectances from both sides of the two tapes, and for input light of both s and p-polarizations. Lastly, an analytic model was developed to understand the reflectance as a function of fluence for each tape material and polarization. Another application that benefits from the advancements of LPA technology is an LPAbased FEL. By sending a high quality electron bunch through an undulator (a periodic structure of positive and negative magnetic poles), the electrons oscillate transversely to the propagation axis and produce radiation. The 1.5 m THUNDER undulator at the BELLA Center has been commissioned using electron beams of 400MeV beams with broad energy spread (35%). To produce a coherent LPA-based FEL, the beam quality would need to improve to sub-percent level energy spread. A seed source could be used to help induce bunching of the electron beam within the undulator. This thesis described the experimental investigation of the physics of using solid-based surface high-harmonic generation (SHHG) from a thin tape as a possible seed source for an FEL. A thin tape placed within centimeters of the undulator's entrance could act as a harmonic generating source, while simultaneously transmitting an electron beam. This removes

FEL (free-electron lasers) undulator technology and synchrotron radiation source requirements

DOE Office of Scientific and Technical Information (OSTI.GOV)

Robinson, K.; Quimby, D.; Slater, J.

This paper describes design and construction considerations of the THUNDER undulator, for use in free-electron laser experiments at visible wavelengths. For the parameters of these experiments, an unusually high degree of optimization of the electron-photon interaction is required and, as a result, THUNDER is built to especially high mechanical and magnetic precision. Except for its narrow magnet gap, the 5-meter THUNDER undulator is quite similar to insertion devices under consideration for the proposed 6-GeV storage ring. The engineering and physics approach adopted for this FEL modulator design is directly applicable to insertion device development. The tolerance limits to THUNDER, establishedmore » by modeling and design and achieved through careful control of mechanical and magnetic errors, are essential to the next generation of insertion devices.« less

Some issues and subtleties in numerical simulation of X-ray FEL's

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fawley, William M.

Part of the overall design effort for x-ray FEL's such as the LCLS and TESLA projects has involved extensive use of particle simulation codes to predict their output performance and underlying sensitivity to various input parameters (e.g. electron beam emittance). This paper discusses some of the numerical issues that must be addressed by simulation codes in this regime. We first give a brief overview of the standard approximations and simulation methods adopted by time-dependent(i.e. polychromatic) codes such as GINGER, GENESIS, and FAST3D, including the effects of temporal discretization and the resultant limited spectral bandpass,and then discuss the accuracies and inaccuraciesmore » of these codes in predicting incoherent spontaneous emission (i.e. the extremely low gain regime).« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gündoğan, M. Tural, E-mail: mugetural@yahoo.com; Yavaş, Ö., E-mail: yavas@ankara.edu.tr; Kaya, Ç., E-mail: c.kaya@ankara.edu.tr

Turkish Accelerator and Radiation Laboratory in Ankara (TARLA) facility is proposed as an IR FEL and Bremsstrahlung facility as the first facility of Turkish Accelerator Center (TAC). TARLA is essentially proposed to generate oscillator mode FEL in 3-250 microns wavelengths range, will consist of normal conducting injector system with 250 keV beam energy, two superconducting RF accelerating modules in order to accelerate the beam 15-40 MeV. The TARLA facility is expected to provide two modes, Continuous wave (CW) and pulsed mode. Longitudinal electron bunch length will be changed between 1 and 10 ps. The bunch charge will be limited by 77pC.more » The design of the Button-type Beam Position Monitor for TARLA IR FEL is studied to operate in 1.3 GHz. Mechanical antenna design and simulations are completed considering electron beam parameters of TARLA. Ansoft HFSS and CST Particle Studio is used to compare with results of simulations.« less

Simultaneous operation of two soft x-ray free-electron lasers driven by one linear accelerator

NASA Astrophysics Data System (ADS)

Faatz, B.; Plönjes, E.; Ackermann, S.; Agababyan, A.; Asgekar, V.; Ayvazyan, V.; Baark, S.; Baboi, N.; Balandin, V.; von Bargen, N.; Bican, Y.; Bilani, O.; Bödewadt, J.; Böhnert, M.; Böspflug, R.; Bonfigt, S.; Bolz, H.; Borges, F.; Borkenhagen, O.; Brachmanski, M.; Braune, M.; Brinkmann, A.; Brovko, O.; Bruns, T.; Castro, P.; Chen, J.; Czwalinna, M. K.; Damker, H.; Decking, W.; Degenhardt, M.; Delfs, A.; Delfs, T.; Deng, H.; Dressel, M.; Duhme, H.-T.; Düsterer, S.; Eckoldt, H.; Eislage, A.; Felber, M.; Feldhaus, J.; Gessler, P.; Gibau, M.; Golubeva, N.; Golz, T.; Gonschior, J.; Grebentsov, A.; Grecki, M.; Grün, C.; Grunewald, S.; Hacker, K.; Hänisch, L.; Hage, A.; Hans, T.; Hass, E.; Hauberg, A.; Hensler, O.; Hesse, M.; Heuck, K.; Hidvegi, A.; Holz, M.; Honkavaara, K.; Höppner, H.; Ignatenko, A.; Jäger, J.; Jastrow, U.; Kammering, R.; Karstensen, S.; Kaukher, A.; Kay, H.; Keil, B.; Klose, K.; Kocharyan, V.; Köpke, M.; Körfer, M.; Kook, W.; Krause, B.; Krebs, O.; Kreis, S.; Krivan, F.; Kuhlmann, J.; Kuhlmann, M.; Kube, G.; Laarmann, T.; Lechner, C.; Lederer, S.; Leuschner, A.; Liebertz, D.; Liebing, J.; Liedtke, A.; Lilje, L.; Limberg, T.; Lipka, D.; Liu, B.; Lorbeer, B.; Ludwig, K.; Mahn, H.; Marinkovic, G.; Martens, C.; Marutzky, F.; Maslocv, M.; Meissner, D.; Mildner, N.; Miltchev, V.; Molnar, S.; Mross, D.; Müller, F.; Neumann, R.; Neumann, P.; Nölle, D.; Obier, F.; Pelzer, M.; Peters, H.-B.; Petersen, K.; Petrosyan, A.; Petrosyan, G.; Petrosyan, L.; Petrosyan, V.; Petrov, A.; Pfeiffer, S.; Piotrowski, A.; Pisarov, Z.; Plath, T.; Pototzki, P.; Prandolini, M. J.; Prenting, J.; Priebe, G.; Racky, B.; Ramm, T.; Rehlich, K.; Riedel, R.; Roggli, M.; Röhling, M.; Rönsch-Schulenburg, J.; Rossbach, J.; Rybnikov, V.; Schäfer, J.; Schaffran, J.; Schlarb, H.; Schlesselmann, G.; Schlösser, M.; Schmid, P.; Schmidt, C.; Schmidt-Föhre, F.; Schmitz, M.; Schneidmiller, E.; Schöps, A.; Scholz, M.; Schreiber, S.; Schütt, K.; Schütz, U.; Schulte-Schrepping, H.; Schulz, M.; Shabunov, A.; Smirnov, P.; Sombrowski, E.; Sorokin, A.; Sparr, B.; Spengler, J.; Staack, M.; Stadler, M.; Stechmann, C.; Steffen, B.; Stojanovic, N.; Sychev, V.; Syresin, E.; Tanikawa, T.; Tavella, F.; Tesch, N.; Tiedtke, K.; Tischer, M.; Treusch, R.; Tripathi, S.; Vagin, P.; Vetrov, P.; Vilcins, S.; Vogt, M.; de Zubiaurre Wagner, A.; Wamsat, T.; Weddig, H.; Weichert, G.; Weigelt, H.; Wentowski, N.; Wiebers, C.; Wilksen, T.; Willner, A.; Wittenburg, K.; Wohlenberg, T.; Wortmann, J.; Wurth, W.; Yurkov, M.; Zagorodnov, I.; Zemella, J.

2016-06-01

Extreme-ultraviolet to x-ray free-electron lasers (FELs) in operation for scientific applications are up to now single-user facilities. While most FELs generate around 100 photon pulses per second, FLASH at DESY can deliver almost two orders of magnitude more pulses in this time span due to its superconducting accelerator technology. This makes the facility a prime candidate to realize the next step in FELs—dividing the electron pulse trains into several FEL lines and delivering photon pulses to several users at the same time. Hence, FLASH has been extended with a second undulator line and self-amplified spontaneous emission (SASE) is demonstrated in both FELs simultaneously. FLASH can now deliver MHz pulse trains to two user experiments in parallel with individually selected photon beam characteristics. First results of the capabilities of this extension are shown with emphasis on independent variation of wavelength, repetition rate, and photon pulse length.

Experimental characterization of the saturating, near infrared, self-amplified spontaneous emission free electron laser: Analysis of radiation properties and electron beam dynamics

NASA Astrophysics Data System (ADS)

Murokh, Alex

2002-01-01

In this work, the main results of the VISA experiment (Visible to Infrared SASE Amplifier) are presented and analyzed. The purpose of the experiment was to build a state-of-the-art single pass self-amplified spontaneous emission (SASE) free electron laser (FEL) based on a high brightness electron beam, and characterize its operation, including saturation, in the near infrared spectral region. This experiment was hosted by Accelerator Test Facility (ATF) at Brookhaven National Laboratory, which is a users facility that provides high brightness relativistic electron beams generated with the photoinjector. During the experiment, SASE FEL performance was studied in two regimes: a long bunch, lower gain operation; and a short bunch high gain regime. The transition between the two conditions was possible due to a novel bunch compression mechanism, which was discovered in the course of the experiment. This compression allowed the variation of peak current in the electron beam before it was launched into the 4-m VISA undulator. In the long bunch regime, a SASE FEL power gain length of 29 cm was obtained, and the generated radiation spectral and statistical properties were characterized. In the short bunch regime, a power gain length of under 18 cm was achieved at 842 nm, which is at least a factor of two shorter than ever previously achieved in this spectral range. Further, FEL saturation was obtained before the undulator exit. The FEL system's performance was measured along the length of the VISA undulator, and in the final state. Statistical, spectral and angular properties of the short bunch SASE radiation have been measured in the exponential gain regime, and at saturation. One of the most important aspects of the data analysis presented in this thesis was the development and use of start-to-end numerical simulations of the experiment. The dynamics of the ATF electron beam was modeled starting from the photocathode, through acceleration, transport, and inside the VISA

Identification and characterization of major cat allergen Fel d 1 mimotopes on filamentous phage carriers.

PubMed

Luzar, Jernej; Molek, Peter; Šilar, Mira; Korošec, Peter; Košnik, Mitja; Štrukelj, Borut; Lunder, Mojca

2016-03-01

Cat allergy is one of the most prevalent allergies worldwide and can lead to the development of rhinitis and asthma. Thus far, only allergen extracts from natural sources have been used for allergen-specific immunotherapy. However, extracts and whole allergens in immunotherapy present an anaphylaxis risk. Identification of allergen epitopes or mimotopes has an important role in development of safe and effective allergen-specific immunotherapy. Moreover, with a suitable immunogenic carrier, the absence of sufficient immune response elicited by short peptides could be surmounted. In this study, we identified five structural mimotopes of the major cat allergen Fel d 1 by immunoscreening with random peptide phage libraries. The mimotopes were computationally mapped to the allergen surface, and their IgE reactivity was confirmed using sera from cat-allergic patients. Importantly, the mimotopes showed no basophil activation of the corresponding cat-allergic patients, which makes them good candidates for the development of hypoallergenic vaccine. As bacteriophage particles are becoming increasingly recognized as immunogenic carriers, we constructed bacteriophage particles displaying multiple copies of each selected mimotope on major phage coat protein. These constructed phages elicited T cell-mediated immune response, which was predominated by the type 1 T cell response. Mimotopes alone contributed to the type 1 T cell response by promoting IL-2 production. Fel d 1 mimotopes, as well as their filamentous phage immunogenic carriers, represent promising candidates in the development of hypoallergenic vaccine against cat allergy. Copyright © 2016 Elsevier Ltd. All rights reserved.

National facilities study. Volume 4: Space operations facilities task group

NASA Technical Reports Server (NTRS)

1994-01-01

The principal objectives of the National Facilities Study (NFS) were to: (1) determine where U.S. facilities do not meet national aerospace needs; (2) define new facilities required to make U.S. capabilities 'world class' where such improvements are in the national interest; (3) define where consolidation and phase-out of existing facilities is appropriate; and (4) develop a long-term national plan for world-class facility acquisition and shared usage. The Space Operations Facilities Task Group defined discrete tasks to accomplish the above objectives within the scope of the study. An assessment of national space operations facilities was conducted to determine the nation's capability to meet the requirements of space operations during the next 30 years. The mission model used in the study to define facility requirements is described in Volume 3. Based on this model, the major focus of the Task Group was to identify any substantive overlap or underutilization of space operations facilities and to identify any facility shortfalls that would necessitate facility upgrades or new facilities. The focus of this initial study was directed toward facility recommendations related to consolidations, closures, enhancements, and upgrades considered necessary to efficiently and effectively support the baseline requirements model. Activities related to identifying facility needs or recommendations for enhancing U.S. international competitiveness and achieving world-class capability, where appropriate, were deferred to a subsequent study phase.

SYNCHROTRON RADIATION, FREE ELECTRON LASER, APPLICATION OF NUCLEAR TECHNOLOGY, ETC.: Study on the characteristics of linac based THz light source

NASA Astrophysics Data System (ADS)

Zhu, Xiong-Wei; Wang, Shu-Hong; Chen, Sen-Yu

2009-10-01

There are many methods based on linac for THz radiation production. As one of the options for the Beijing Advanced Light, an ERL test facility is proposed for THz radiation. In this test facility, there are 4 kinds of methods to produce THz radiation: coherent synchrotron radiation (CSR), synchrotron radiation (SR), low gain FEL oscillator, and high gain SASE FEL. In this paper, we study the characteristics of the 4 kinds of THz light sources.

Plasma channel undulator excited by high-order laser modes

DOE PAGES

Wang, J. W.; Schroeder, C. B.; Li, R.; ...

2017-12-04

The possibility of utilizing plasma undulators and plasma accelerators to produce compact ultraviolet and X-ray sources, has attracted considerable interest for a few decades. This interest has been driven by the great potential to decrease the threshold for accessing such sources, which are mainly provided by a few dedicated large-scale synchrotron or free-electron laser (FEL) facilities. However, the broad radiation bandwidth of such plasma devices limits the source brightness and makes it difficult for the FEL instability to develop. Here in this paper, using multi-dimensional particle-in-cell (PIC) simulations, we demonstrate that a plasma undulator generated by the beating of amore » mixture of high-order laser modes propagating inside a plasma channel, leads to a few percent radiation bandwidth. The strength of the undulator can reach unity, the period can be less than a millimeter, and the number of undulator periods can be significantly increased by a phase locking technique based on the longitudinal tapering. Polarization control of such an undulator can be achieved by appropriately choosing the phase of the modes. According to our results, in the fully beam loaded regime, the electron current in the plasma undulator can reach 0.3 kA level, making such an undulator a potential candidate towards a table-Top FEL.« less

Plasma channel undulator excited by high-order laser modes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, J. W.; Schroeder, C. B.; Li, R.

The possibility of utilizing plasma undulators and plasma accelerators to produce compact ultraviolet and X-ray sources, has attracted considerable interest for a few decades. This interest has been driven by the great potential to decrease the threshold for accessing such sources, which are mainly provided by a few dedicated large-scale synchrotron or free-electron laser (FEL) facilities. However, the broad radiation bandwidth of such plasma devices limits the source brightness and makes it difficult for the FEL instability to develop. Here in this paper, using multi-dimensional particle-in-cell (PIC) simulations, we demonstrate that a plasma undulator generated by the beating of amore » mixture of high-order laser modes propagating inside a plasma channel, leads to a few percent radiation bandwidth. The strength of the undulator can reach unity, the period can be less than a millimeter, and the number of undulator periods can be significantly increased by a phase locking technique based on the longitudinal tapering. Polarization control of such an undulator can be achieved by appropriately choosing the phase of the modes. According to our results, in the fully beam loaded regime, the electron current in the plasma undulator can reach 0.3 kA level, making such an undulator a potential candidate towards a table-Top FEL.« less

Investigation of the Effects of MIR-FELIrradiation on the Photoluminescence of Titanium Dioxides

NASA Astrophysics Data System (ADS)

Sonobe, T.; Bakr, M.; Yoshida, K.; Higashimura, K.; Kinjo, R.; Hachiya, K.; Kii, T.; Masuda, K.; Ohgaki, H.

2010-02-01

A mid-infrared free electron laser (MIR-FEL: 5 μm-20 μm) facility (KU-FEL: Kyoto University Free Electron Laser) has been constructed in Institute of Advanced Energy Kyoto University, and first laser saturation at 13.2 μm was achieved in May 2008. Currently, we have started to develop the application of MIR-FEL in the field of energy and material science. This study aimed at investigating the feasibility for the development of new evaluation technique of electron-phonon interaction in metal oxides by MIR-FEL. A preliminary result of electrical and optical properties of titanium dioxides was presented.

Purdue University National Biomedical Tracer Facility: Project definition phase. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Green, M.A.

The proposed National Biomedical Tracer Facility (NBTF) will house a high-current accelerator dedicated to production of short-lived radionuclides for biomedical and scientific research. The NBTF will play a vital role in repairing and maintaining the United States` research infrastructure for generation of essential accelerator-based radioisotopes. If properly designed and managed, the NBTF should also achieve international recognition as a Center-of-Excellence for research on radioisotope production methods and for associated education and training. The current report documents the results of a DOE-funded NBTF Project Definition Phase study carried out to better define the technical feasibility and projected costs of establishing andmore » operating the NBTF. This report provides an overview of recommended Facility Design and Specifications, including Accelerator Design, Building Design, and the associated Construction Cost Estimates and Schedule. It is recommended that the NBTF be established as an integrated, comprehensive facility for meeting the diverse production, research, and educational missions set forth in previous documents. Based on an analysis of the projected production demands that will be placed on the NBTF, it appears that a 70 MeV, 1 mA, negative ion cyclotron will offer a good balance between production capabilities and the costs of accelerator purchase and operation. A preliminary architectural plan is presented for a facility designed specifically to fulfill the functions of the NBTF in a cost-effective manner. This report also presents a detailed analysis of the Required Federal State, and Local Permits that may be needed to establish the NBTF, along with schedules and cost estimates for obtaining these permits. The Handling, Storage, and Disposal of Radioactive Waste will pose some significant challenges in the operation of the NBTF, but at this stage of planning the associated problems do not appear to be prohibitive.« less

Simultaneous operation of two soft x-ray free-electron lasers driven by one linear accelerator

DOE PAGES

Faatz, B.; Plönjes, E.; Ackermann, S.; ...

2016-06-20

Extreme-ultraviolet to x-ray free-electron lasers (FELs) in operation for scientific applications are up to now single-user facilities. While most FELs generate around 100 photon pulses per second, FLASH at DESY can deliver almost two orders of magnitude more pulses in this time span due to its superconducting accelerator technology. This makes the facility a prime candidate to realize the next step in FELs—dividing the electron pulse trains into several FEL lines and delivering photon pulses to several users at the same time. Hence, FLASH has been extended with a second undulator line and self-amplified spontaneous emission (SASE) is demonstrated inmore » both FELs simultaneously. Here, FLASH can now deliver MHz pulse trains to two user experiments in parallel with individually selected photon beam characteristics. First results of the capabilities of this extension are shown with emphasis on independent variation of wavelength, repetition rate, and photon pulse length.« less

Shot noise startup of the 6 NM SASE FEL at the Tesla Test Facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pierini, P.; Fawley, W.M.

We present here an analysis of the shot noise startup of the 6 nm SASE FEI proposal at the TESLA Test Facility in DESY The statistical of the saturation length and output power due to the intrinsic randomness of the noise startup are investigated with the use of the 2D time dependent code GINGER, that takes into account propagation effects and models shot noise. We then provide estimates for the spectral contents and linewidth of the emitted radiation and describe its spiking characteristics. The output radiation will develop superradiant spikes seeded by the shot noise in the electron beam, whichmore » can entrance the average emitted power at the expense of some spectral broadening.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ratner, D.; Behrens, C.; Ding, Y.

The microbunching instability (MBI) is a well known problem for high brightness electron beams and has been observed at accelerator facilities around the world. Free-electron lasers (FELs) are particularly susceptible to MBI, which can distort the longitudinal phase space and increase the beam’s slice energy spread (SES). Past studies of MBI at the Linac Coherent Light Source (LCLS) relied on optical transition radiation to infer the existence of microbunching. With the development of the x-band transverse deflecting cavity (XTCAV), we can for the first time directly image the longitudinal phase space at the end of the accelerator and complete amore » comprehensive study of MBI, revealing both detailed MBI behavior as well as insights into mitigation schemes. The fine time resolution of the XTCAV also provides the first LCLS measurements of the final SES, a critical parameter for many advanced FEL schemes. As a result, detailed MBI and SES measurements can aid in understanding MBI mechanisms, benchmarking simulation codes, and designing future high- brightness accelerators.« less

Time-resolved imaging of the microbunching instability and energy spread at the Linac Coherent Light Source

DOE PAGES

Ratner, D.; Behrens, C.; Ding, Y.; ...

2015-03-09

The microbunching instability (MBI) is a well known problem for high brightness electron beams and has been observed at accelerator facilities around the world. Free-electron lasers (FELs) are particularly susceptible to MBI, which can distort the longitudinal phase space and increase the beam’s slice energy spread (SES). Past studies of MBI at the Linac Coherent Light Source (LCLS) relied on optical transition radiation to infer the existence of microbunching. With the development of the x-band transverse deflecting cavity (XTCAV), we can for the first time directly image the longitudinal phase space at the end of the accelerator and complete amore » comprehensive study of MBI, revealing both detailed MBI behavior as well as insights into mitigation schemes. The fine time resolution of the XTCAV also provides the first LCLS measurements of the final SES, a critical parameter for many advanced FEL schemes. As a result, detailed MBI and SES measurements can aid in understanding MBI mechanisms, benchmarking simulation codes, and designing future high- brightness accelerators.« less

Endangered Languages and Education. Proceedings of the Foundation for Endangered Languages (FEL) Conference (3rd, Maynooth, Ireland, September 17-19, 1999).

ERIC Educational Resources Information Center

Ostler, Nicholas, Ed.

The theme of the third annual Foundation for Endangered Languages (FEL) Conference was Endangered Languages and Education, focusing on how education can be used to promote, resist, and reverse the decline of a language. The conference papers are broken into several sections covering the topic from a variety of aspects and perspectives.…

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hunter, Mark S.; Yoon, Chun Hong; DeMirci, Hasan

Structural information about biological macromolecules near the atomic scale provides important insight into the functions of these molecules. To date, X-ray crystallography has been the predominant method used for macromolecular structure determination. However, challenges exist when solving structures with X-rays, including the phase problem and radiation damage. X-ray-free electron lasers (X-ray FELs) have enabled collection of diffraction information before the onset of radiation damage, yet the majority of structures solved at X-ray FELs have been phased using external information via molecular replacement. De novo phasing at X-ray FELs has proven challenging due in part to per-pulse variations in intensity andmore » wavelength. Here we report the solution of a selenobiotinyl-streptavidin structure using phases obtained by the anomalous diffraction of selenium measured at a single wavelength (Se-SAD) at the Linac Coherent Light Source. Finally, our results demonstrate Se-SAD, routinely employed at synchrotrons for novel structure determination, is now possible at X-ray FELs.« less

The accomplishments of lithium target and test facility validation activities in the IFMIF/EVEDA phase

NASA Astrophysics Data System (ADS)

Arbeiter, Frederik; Baluc, Nadine; Favuzza, Paolo; Gröschel, Friedrich; Heidinger, Roland; Ibarra, Angel; Knaster, Juan; Kanemura, Takuji; Kondo, Hiroo; Massaut, Vincent; Saverio Nitti, Francesco; Miccichè, Gioacchino; O'hira, Shigeru; Rapisarda, David; Sugimoto, Masayoshi; Wakai, Eiichi; Yokomine, Takehiko

2018-01-01

As part of the engineering validation and engineering design activities (EVEDA) phase for the international fusion materials irradiation facility IFMIF, major elements of a lithium target facility and the test facility were designed, prototyped and validated. For the lithium target facility, the EVEDA lithium test loop was built at JAEA and used to test the stability (waves and long term) of the lithium flow in the target, work out the startup procedures, and test lithium purification and analysis. It was confirmed by experiments in the Lifus 6 plant at ENEA that lithium corrosion on ferritic martensitic steels is acceptably low. Furthermore, complex remote handling procedures for the remote maintenance of the target in the test cell environment were successfully practiced. For the test facility, two variants of a high flux test module were prototyped and tested in helium loops, demonstrating their good capabilities of maintaining the material specimens at the desired temperature with a low temperature spread. Irradiation tests were performed for heated specimen capsules and irradiation instrumentation in the BR2 reactor at SCK-CEN. The small specimen test technique, essential for obtaining material test results with limited irradiation volume, was advanced by evaluating specimen shape and test technique influences.

It's up to you: a multi-message, phased driver facility campaign to increase organ donation registration rates in Illinois.

PubMed

Quick, Brian; Harrison, Tyler R; King, Andy J; Bosch, Dave

2013-01-01

The present project applied successful strategies employed in previous driver facility campaigns occurring during the inception of a registry to examine whether these approaches are effective in growing a mature registry, a registry where the majority of individuals have had the opportunity to register as an organ donor. Driver facilities (N = 40) in Illinois with high (n = 20) and low (n = 20) organ donation registration percentages were selected and served as either intervention or control sites for the campaign. Among facilities with historically high and low registration percentages, support for the campaign was found with the intervention facilities experiencing higher organ donation registration rates compared with control facilities. In addition, the results provide partial support for the effectiveness of employing a multi-message, phased driver facility intervention in states with a mature registry. The practical implications of utilizing driver facility campaigns in states with an established first-person consent registry also are discussed. © 2013 John Wiley & Sons A/S.

High-power infrared and ultraviolet free electron lasers at CEBAF

DOE Office of Scientific and Technical Information (OSTI.GOV)

Byung Yunn; Charles Sinclair; Christoph Leemann

1992-06-15

In response to requirements for national laboratory technology transfer, CEBAF has proposed an industrial R&D initiative: a Free Electron Laser(FEL) User Facility based on an infrared FEL and an ultraviolet FEL, with the injector and the north linac of the CEBAF superconducting,recirculating accelerator serving as drivers. The initiative is a collaborative effort with four U.S. corporate partners and capitalizes on CEBAF'ssuperconducting rf technology. The FELs will provide monochromatic, tunable (3.6 to 1.7 ¿m and 150 to 260 nm), high-average-power (-kW) lightfor technical applications and basic science studies. FEL capabilities will be competitive with those of similar initiatives worldwide. FEL operationmore » willnot impair beam delivered to CEBAF's nuclear physics experiments. Substational commitments are in hand from the industray partners and theCommonwealth of Virgina for cost-sharing the project with the Federal Government.« less

High-power infrared and ultraviolet free electron lasers at CEBAF

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dylla, H.F.; Bisognano, J.J.; Douglas, D.

1992-12-05

In response to requirements for national laboratory technology transfer, CEBAF has proposed an industrial R D initiative: a Free Electron Laser (FEL) User Facility based on an infrared FEL and an ultraviolet FEL, with the injector and the north linac of the CEBAF superconducting, recirculating accelerator serving as drivers. The initiative is a collaborative effort with four U.S. corporate partners and capitalizes on CEBAF's superconducting rf technology. The FELs will provide monochromatic, tunable (3.6 to 1.7 [mu]m and 150 to 260 nm), high-average-power (-kW) light for technical applications and basic science studies. FEL capabilities will be competitive with those ofmore » similar initiatives worldwide. FEL operation will not impair beam delivered to CEBAF's nuclear physics experiments. Substational commitments are in hand from the industray partners and the Commonwealth of Virgina for cost-sharing the project with the Federal Government.« less

Harmonic lasing in x-ray free electron lasers

NASA Astrophysics Data System (ADS)

Schneidmiller, E. A.; Yurkov, M. V.

2012-08-01

Harmonic lasing in a free electron laser with a planar undulator (under the condition that the fundamental frequency is suppressed) might be a cheap and efficient way of extension of wavelength ranges of existing and planned x-ray free electron laser (FEL) facilities. Contrary to nonlinear harmonic generation, harmonic lasing can provide much more intense, stable, and narrow-band FEL beam which is easier to handle due to the suppressed fundamental frequency. In this paper we perform a parametrization of the solution of the eigenvalue equation for lasing at odd harmonics, and present an explicit expression for FEL gain length, taking into account all essential effects. We propose and discuss methods for suppression of the fundamental harmonic. We also suggest a combined use of harmonic lasing and lasing at the retuned fundamental wavelength in order to reduce bandwidth and to increase brilliance of x-ray beam at saturation. Considering 3rd harmonic lasing as a practical example, we come to the conclusion that it is much more robust than usually thought, and can be widely used in the existing or planned x-ray FEL (XFEL) facilities. In particular, Linac Coherent Light Source (LCLS) after a minor modification can lase to saturation at the 3rd harmonic up to the photon energy of 25-30 keV providing multigigawatt power level and narrow bandwidth. As for the European XFEL, harmonic lasing would allow one to extend operating range (ultimately up to 100 keV), to reduce FEL bandwidth and to increase brilliance, to enable two-color operation for pump-probe experiments, and to provide more flexible operation at different electron energies. Similar improvements can be realized in other x-ray FEL facilities with gap-tunable undulators like FLASH II, SACLA, LCLS II, etc. Harmonic lasing can be an attractive option for compact x-ray FELs (driven by electron beams with a relatively low energy), allowing the use of the standard undulator technology instead of small-gap in

Final work plan : phase II investigation of potential contamination at the former CCC/USDA grain storage facility in Savannah, Missouri.

DOE Office of Scientific and Technical Information (OSTI.GOV)

LaFreniere, L. M.; Environmental Science Division

Agency of the USDA and the MoDNR, to address carbon tetrachloride contamination potentially associated with a number of former CCC/USDA grain storage facilities in Missouri. The site characterization at Savannah is being conducted on behalf of the CCC/USDA by the Environmental Science Division of Argonne National Laboratory. The investigation at Savannah is being conducted in phases. This approach is being used by the CCC/USDA and Argonne, with the approval of the MoDNR, so that information obtained and interpretations developed during each incremental stage of the investigation can be used most effectively to guide subsequent phases of the program. Phase I of the Savannah program was conducted in October-November 2007 and January 2008 (Argonne 2007a, 2008). This site-specific Work Plan provides a brief summary of the Phase I findings and the results of groundwater level monitoring that has been ongoing since completion of the Phase I study and also outlines technical objectives, investigation tasks, and investigation methods for Phase II of the site characterization at Savannah.« less

The Status of Turkish Accelerator Center Test Facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yavas, Oe.

2007-04-23

Recently, conceptual design of Turkic Accelerator Center (TAC) proposal was completed. Main goal of this proposal is a charm factory that consists of a linac-ring type electron-positron collider. In addition, synchrotron radiation from the positron ring and free electron laser from the electron linac are proposed. The project related with this proposal has been accepted by Turkish government. It is planned that the Technical Design Report of TAC will have been written in next three years. In this period, an infrared oscillator free electron laser (IR FEL) will be constructed as a test facility for TAC. 20 and 50 MeVmore » electron energies will be used to obtain infra red free electron laser. The main parameters of the electron linac, the optical cavities and the free electron laser were determined. The possible use of obtained laser beam in basic and applied research areas such as biotechnology, nanotechnology, semiconductors and photo chemistry were stated.« less

Gas-Grain Simulation Facility (GGSF). Volume 1: Stage 1 facility definition studies

NASA Technical Reports Server (NTRS)

Gat, Nahum

1993-01-01

The Gas-Grain Simulation Facility (GGSF) is a facility-type payload to be included in the Space Station Freedom (SSF). The GGSF is a multidisciplinary facility that will accommodate several classes of experiments, including exobiology, planetary science, atmospheric science, and astrophysics. The physical mechanisms envisioned to be investigated include crystal growth, aggregation, nucleation, coagulation, condensation, collisions, fractal growth, cycles of freezing and evaporation, scavenging, longevity of bacteria, and more. TRW performed a Phase A study that included analyses of the science and technical (S&T) requirements, the development of facility functional requirements, and a conceptual design of the facility. The work that was performed under Stage 1 of the Phase A study and the results to date are summarized. In this stage, facility definition studies were conducted in sufficient detail to establish the technical feasibility of the candidate strawman experiments. The studies identified technical difficulties, identified required facility subsystems, surveyed existing technology studies and established preliminary facility weight, volume, power consumption, data systems, interface definition, and crew time requirements. The results of this study served as the basis for Stage 2 of the Phase A study in which a conceptual design and a reference design were performed. The results also served as a basis for a related study for a Gas-Grain Simulation Experiment Module (GGSEM), which is an apparatus intended to perform a subset of the GGSF experiments on board a low-Earth-orbiting platform.

Multi-dimensional free-electron laser simulation codes : a comparison study.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Biedron, S. G.; Chae, Y. C.; Dejus, R. J.

A self-amplified spontaneous emission (SASE) free-electron laser (FEL) is under construction at the Advanced Photon Source (APS). Five FEL simulation codes were used in the design phase: GENESIS, GINGER, MEDUSA, RON, and TDA3D. Initial comparisons between each of these independent formulations show good agreement for the parameters of the APS SASE FEL.

Multi-Dimensional Free-Electron Laser Simulation Codes: A Comparison Study

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nuhn, Heinz-Dieter

A self-amplified spontaneous emission (SASE) free-electron laser (FEL) is under construction at the Advanced Photon Source (APS). Five FEL simulation codes were used in the design phase: GENESIS, GINGER, MEDUSA, RON, and TDA3D. Initial comparisons between each of these independent formulations show good agreement for the parameters of the APS SASE FEL.

Phase-Sensitive Reflective Imaging Device in the mm-wave and Terahertz Regions

NASA Astrophysics Data System (ADS)

Gallerano, Gian Piero; Doria, Andrea; Germini, Marzia; Giovenale, Emilio; Messina, Giovanni; Spassovsky, Ivan P.

2009-12-01

Two Free Electron Laser sources have been developed at ENEA-Frascati for a variety of applications: A Compact Free Electron Laser (C-FEL) that provides coherent radiation in the frequency range between 90 and 150 GHz Gallerano et al. (Infrared Phys. and Techn. 40:161, 1999), and a second source, FEL-CATS, which utilizes a peculiar radio-frequency structure to generate coherent emission in the range 0.4 to 0.7 THz Doria et al. (Phys. Rev. Lett 93:264801, 2004). The high peak power of several kW in 15 to 50 ps pulses, makes these sources particularly suitable for the assessment of exposure limits in biological systems and for long range detection. In this paper we present a phase-sensitive reflective imaging device in the mm-wave and THz regions, which has proven to be a valuable tool in the biological Ramundo-Orlando et al. (Bioelectromagnetics 28:587-598, 2007), environmental Doria et al. (2005) and art conservation fields Gallerano et al. (2008). Different setups have been tested at different levels of spatial resolution to image objects from a few centimeter square to larger sizes. Images have been compared to identify and characterize the contrast mechanism.

JUNGFRAU 0.2: prototype characterization of a gain-switching, high dynamic range imaging system for photon science at SwissFEL and synchrotrons

NASA Astrophysics Data System (ADS)

Jungmann-Smith, J. H.; Bergamaschi, A.; Cartier, S.; Dinapoli, R.; Greiffenberg, D.; Johnson, I.; Maliakal, D.; Mezza, D.; Mozzanica, A.; Ruder, Ch; Schaedler, L.; Schmitt, B.; Shi, X.; Tinti, G.

2014-12-01

JUNGFRAU (adJUstiNg Gain detector FoR the Aramis User station) is a two-dimensional pixel detector for photon science applications at free electron lasers and synchrotron light sources. It is developed for the SwissFEL currently under construction at the Paul Scherrer Institute, Switzerland. Characteristics of this application-specific integrating circuit readout chip include single photon sensitivity and low noise over a dynamic range of over four orders of magnitude of photon input signal. These characteristics are achieved by a three-fold gain-switching preamplifier in each pixel, which automatically adjusts its gain to the amount of charge deposited on the pixel. The final JUNGFRAU chip comprises 256 × 256 pixels of 75 × 75 μm2 each. Arrays of 2 × 4 chips are bump-bonded to monolithic detector modules of about 4 × 8 cm2. Multi-module systems up to 16 Mpixels are planned for the end stations at SwissFEL. A readout rate in excess of 2 kHz is anticipated, which serves the readout requirements of SwissFEL and enables high count rate synchrotron experiments with a linear count rate capability of > 20 MHz/pixel. Promising characterization results from a 3.6 × 3.6 mm2 prototype (JUNGFRAU 0.2) with fluorescence X-ray, infrared laser and synchrotron irradiation are shown. The results include an electronic noise as low as 100 electrons root-mean-square, which enables single photon detection down to X-ray energies of about 2 keV. Noise below the Poisson fluctuation of the photon number and a linearity error of the pixel response of about 1% are demonstrated. First imaging experiments successfully show automatic gain switching. The edge spread function of the imaging system proves to be comparable in quality to single photon counting hybrid pixel detectors.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Litvinenko,V.; Yakimenko, V.

We propose undertaking a demonstration experiment on suppressing spontaneous undulator radiation from an electron beam at BNL's Accelerator Test Facility (ATF). We describe the method, the proposed layout, and a possible schedule. There are several advantages in strongly suppressing shot noise in the electron beam, and the corresponding spontaneous radiation. The self-amplified spontaneous (SASE) emission originating from shot noise in the electron beam is the main source of noise in high-gain FEL amplifiers. It may negatively affect several HG FEL applications ranging from single- to multi-stage HGHG FELs. SASE saturation also imposes a fundamental hard limit on the gain ofmore » an FEL amplifier in a coherent electron-cooling scheme. A novel active method for suppressing shot noise in relativistic electron beams by many orders-of-magnitude was recently proposed. While theoretically such strong suppression appears feasible, the performance and applicability of this novel method must be evaluated experimentally. Several practical questions about the proposed noise suppressor, such as 3D effects and/or sensitivity to the e-beam parameters also require experimental clarification. To do this, we propose here a proof-of-principle experiment using elements of the VISA FEL at BNL's Accelerator Test Facility.« less

The Physics and Applications of High Brightness Beams: Working Group C Summary on Applications to FELS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nuhn, Heinz-Dieter

2003-03-19

This is the summary of the activities in working group C, ''Application to FELs,'' which was based in the Bithia room at the Joint ICFA Advanced Accelerator and Beam Dynamics Workshop on July 1-6, 2002 in Chia Laguna, Sardinia, Italy. Working group C was small in relation to the other working groups at that workshop. Attendees include Enrica Chiadroni, University of Rome ape with an identical pulse length. ''La Sapienza'', Luca Giannessi, ENEA, Steve Lidia, LBNL, Vladimir Litvinenko, Duke University, Patrick Muggli, UCLA, Alex Murokh, UCLA, Heinz-Dieter Nuhn, SLAC, Sven Reiche, UCLA, Jamie Rosenzweig, UCLA, Claudio Pellegrini, UCLA, Susan Smith,more » Daresbury Laboratory, Matthew Thompson, UCLA, Alexander Varfolomeev, Russian Research Center, plus a small number of occasional visitors. The working group addressed a total of nine topics. Each topic was introduced by a presentation, which initiated a discussion of the topic during and after the presentation. The speaker of the introductory presentation facilitated the discussion. There were six topics that were treated in stand-alone sessions of working group C. In addition, there were two joint sessions, one with working group B, which included one topic, and one with working group C, which included two topics. The presentations that were given in the joint sessions are summarized in the working group summary reports for groups B and D, respectively. This summary will only discuss the topics that were addressed in the stand-alone sessions, including Start-To-End Simulations, SASE Experiment, PERSEO, ''Optics Free'' FEL Oscillators, and VISA II.« less

Three years of biomedical FEL use in medicine and surgery How far have we come?

NASA Astrophysics Data System (ADS)

Jean, Benedikt

1997-02-01

Since the FEL has been made available for biophysical research in the IR, it has revolutionized the optimization strategies of laser-tissue interaction and the minimizing of adverse effects, in particular for photoablative use in surgery. Its tunability together with the free combination of wavelength and energy made it an efficient research tool, allowing the reduction of risks and costs of preclinical biomedical research. New computer-assisted surgical techniques evolved and the broader data basis of IR photothermal ablation allows more accurate predictive modelling of the efficiency and the adverse effects of photoablation. New applications for diagnostic imaging as well as the first clinical applications in neurosurgery lay ahead.

Multipurpose end-station for coherent diffraction imaging and scattering at FERMI@Elettra free-electron laser facility.

PubMed

Capotondi, Flavio; Pedersoli, Emanuele; Bencivenga, Filippo; Manfredda, Michele; Mahne, Nicola; Raimondi, Lorenzo; Svetina, Cristian; Zangrando, Marco; Demidovich, Alexander; Nikolov, Ivaylo; Danailov, Miltcho; Masciovecchio, Claudio; Kiskinova, Maya

2015-05-01

The Diffraction and Projection Imaging (DiProI) beamline at FERMI, the Elettra free-electron laser (FEL), hosts a multi-purpose station that has been opened to users since the end of 2012. This paper describes the core capabilities of the station, designed to make use of the unique features of the FERMI-FEL for performing a wide range of static and dynamic scattering experiments. The various schemes for time-resolved experiments, employing both soft X-ray FEL and seed laser IR radiation are presented by using selected recent results. The ongoing upgrade is adding a reflection geometry setup for scattering experiments, expanding the application fields by providing both high lateral and depth resolution.

Facile preparation of an alternating copolymer-based high molecular shape-selective organic phase for reversed-phase liquid chromatography.

PubMed

Mallik, Abul K; Noguchi, Hiroki; Rahman, Mohammed Mizanur; Takafuji, Makoto; Ihara, Hirotaka

2018-06-22

chromatography (SEC) before grafting onto silica surface. Moreover, both of the monomers were commercially available. Therefore, the technique of preparation was very facile and better separation was achieved with the Sil-alt-T phase compared to the ODS, C 30 and other previously reported alternating copolymer-based columns. Copyright © 2018 Elsevier B.V. All rights reserved.

77 FR 43086 - Solicitation of Written Comments on Draft Phase 3 Long-Term Care Facilities Strategy/Module for...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-23

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Solicitation of Written Comments on Draft Phase 3 Long-Term Care Facilities Strategy/Module for Inclusion in the National Action Plan To Prevent Healthcare-Associated Infections: Roadmap to Elimination AGENCY: Department of Health and Human Services, Office of the...

Validation of Maturity Offset in the Fels Longitudinal Study.

PubMed

Malina, Robert M; Choh, Audrey C; Czerwinski, Stefan A; Chumlea, Wm Cameron

2016-08-01

Sex-specific equations for predicting maturity offset, time before or after peak height velocity (PHV), were evaluated in 63 girls and 74 boys from the Fels Longitudinal Study. Serially measured heights (0.1 cm), sitting heights (0.1 cm), weights (0.1 kg), and estimated leg lengths (0.1 cm) from 8 to 18 years were used. Predicted age at PHV (years) was calculated as the difference between chronological age (CA) and maturity offset. Actual age at PHV for each child was derived with a triple logistic model (Bock-Thissen-du Toit). Mean predicted maturity offset was negative and lowest at 8 years and increased linearly with increasing CA. Predicted ages at PHV increased linearly with CA from 8 to 18 years in girls and from 8 to 13 years in boys; predictions varied within relatively narrow limits from 12 to 15 years and then increased to 18 years in boys. Differences between predicted and actual ages at PHV among youth of contrasting maturity status were significant across the age range in both sexes. Dependence of predicted age at PHV upon CA at prediction and on actual age at PHV limits its utility as an indicator of maturity timing and in sport talent programs.

Global environment facility: Independent evaluation of the pilot phase; Fonds pour l`environnement mondial: evaluation independante de la phase pilote

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1994-12-31

This study responds to a request by participants in the Global Environment Facility (GEF) for an independent evaluation of the pilot phase. It profiles the GEF, discusses its policy framework, and reviews project development procedures and the strategies and projects in each of the GEF`s four focal areas. The study concludes that fundamental changes must occur and recommends specific reforms, such as articulating more clearly the GEF`s mandate, objectives, and strategies; addressing deficiencies in meeting its global focus; improving capacities and procedures within implementing agencies for managing the portfolio; and increasing non-government organization (NGO), country and community-level participation.

Use of the CEBAF Accelerator for IR and UV Free Electron Lasers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yunn, Byung; Sinclair, Charles; Leemann, Christoph

1992-08-01

The CEBAF superconducting linac is capable of accelerating electron beams suitable for driving high-power free-electron lasers. The 45 MeV injector linac with a 6 cm period wiggler can produce kilowatt output powers of infrared light (3.6-17 micrometer), while the 400 MeV north linac can produce ultraviolet light (~200 nm) at similar powers. The FELs require the addition of a high-peak intensity electron source (~ 60 A peak current) and extraction beam lines to wigglers with appropriate electron and photon optics. FEL operation is compatible with simultaneous baseline CEBAF nuclear physics operation. A design for a CEBAF-based FEL facility has beenmore » developed. The current status of the FEL project is reported.« less

Facile room-temperature solution-phase synthesis of a spherical covalent organic framework for high-resolution chromatographic separation.

PubMed

Yang, Cheng-Xiong; Liu, Chang; Cao, Yi-Meng; Yan, Xiu-Ping

2015-08-07

A simple and facile room-temperature solution-phase synthesis was developed to fabricate a spherical covalent organic framework with large surface area, good solvent stability and high thermostability for high-resolution chromatographic separation of diverse important industrial analytes including alkanes, cyclohexane and benzene, α-pinene and β-pinene, and alcohols with high column efficiency and good precision.

RF Couplers for Normal-Conducting Photoinjector of High-Power CW FEL

NASA Astrophysics Data System (ADS)

Kurennoy, Sergey; Schrage, Dale; Wood, Richard; Schultheiss, Tom; Rathke, John; Young, Lloyd

2004-05-01

A high-current emittance-compensated RF photoinjector is a key enabling technology for a high-power CW FEL. A preliminary design of a normal-conducting, 2.5-cell pi-mode, 700-MHz CW RF photoinjector that will be build for demonstration purposes, is completed. This photoinjector will be capable of accelerating a 100-mA electron beam (3 nC per bunch at 35 MHz bunch repetition rate) to 2.7 MeV while providing an emittance below 7 mm-mrad at the wiggler. More than 1 MW of RF power will be fed into the photoinjector cavity through two ridge-loaded tapered waveguides. The waveguides are coupled to the cavity by "dog-bone" irises cut in a thick wall. Due to CW operation of the photoinjector, the cooling of the coupler irises is a rather challenging thermal management project. This paper presents results of a detailed electromagnetic modeling of the coupler-cavity system, which has been performed to select the coupler design that minimizes the iris heating due to RF power loss in its walls.

Analyses in Support of Risk-Informed Natural Gas Vehicle Maintenance Facility Codes and Standards: Phase II.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Blaylock, Myra L.; LaFleur, Chris Bensdotter; Muna, Alice Baca

Safety standards development for maintenance facilities of liquid and compressed natural gas fueled vehicles is required to ensure proper facility design and operating procedures. Standard development organizations are utilizing risk-informed concepts to develop natural gas vehicle (NGV) codes and standards so that maintenance facilities meet acceptable risk levels. The present report summarizes Phase II work for existing NGV repair facility code requirements and highlights inconsistencies that need quantitative analysis into their effectiveness. A Hazardous and Operability study was performed to identify key scenarios of interest using risk ranking. Detailed simulations and modeling were performed to estimate the location and behaviormore » of natural gas releases based on these scenarios. Specific code conflicts were identified, and ineffective code requirements were highlighted and resolutions proposed. These include ventilation rate basis on area or volume, as well as a ceiling offset which seems ineffective at protecting against flammable gas concentrations. ACKNOWLEDGEMENTS The authors gratefully acknowledge Bill Houf (SNL -- Retired) for his assistance with the set-up and post-processing of the numerical simulations. The authors also acknowledge Doug Horne (retired) for his helpful discussions. We would also like to acknowledge the support from the Clean Cities program of DOE's Vehicle Technology Office.« less

Centrifuge Facility Conceptual System Study. Volume 1: Facility overview and habitats

NASA Technical Reports Server (NTRS)

Synnestvedt, Robert (Editor)

1990-01-01

The results are presented for a NASA Phase 1 study conducted from mid 1987 through mid 1989 at Ames Research Center. The Centrifuge Facility is the major element of the biological research facility for the implementation of NASA's Life Science Research Program on Space Station Freedom using non-human specimens (such as small primates, rodents, plants, insects, cell tissues). Five systems are described which comprise the Facility: habitats, holding units, centrifuge, glovebox, and service unit. Volume 1 presents a facility overview and describes the habitats - modular units which house living specimens.

Progress toward the Wisconsin Free Electron Laser

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bisognano, Joseph; Eisert, D; Fisher, M V

2011-03-01

The University of Wisconsin-Madison/Synchrotron Radiation Center is advancing its design for a seeded VUV/soft X-ray Free Electron Laser facility called WiFEL. To support this vision of an ultimate light source, we are pursuing a program of strategic R&D addressing several crucial elements. This includes development of a high repetition rate, VHF superconducting RF electron gun, R&D on photocathode materials by ARPES studies, and evaluation of FEL facility architectures (e.g., recirculation, compressor scenarios, CSR dechirping, undulator technologies) with the specific goal of cost containment. Studies of high harmonic generation for laser seeding are also planned.

Phase I Investigations at the Former CCC/USDA Grain Storage Facility in Montgomery City, Missouri, in 2010-2011

DOE Office of Scientific and Technical Information (OSTI.GOV)

LaFreniere, Lorraine M.

This report presents the technical findings of Phase I of Argonne’s studies. The Phase I field investigation was initiated on October 18, 2010. The work was conducted in accord with (1) the final site-specific Phase I Work Plan for Montgomery City (Argonne 2010; approved by the MDNR [2010]); (2) applicable Missouri regulations; and (3) the standard operating procedures, quality assurance/quality control (QA/QC) measures, and general health and safety policies outlined in the Master Work Plan (Argonne 2002) for operations in Kansas, which was reviewed by the MDNR and accepted for current use. A draft master plan specific to work inmore » Missouri and a set of draft standard operating procedures are in review with the MDNR. The site-specific Work Plan for Montgomery City (Argonne 2010) (1) summarizes the pre-existing knowledge base for the Montgomery City investigation site compiled by Argonne and (2) describes the site-specific technical objectives and the intended scope of work developed for the first phase of the investigation. Three primary technical objectives were identified for the Phase I studies, as follows: 1. Update the presently identified inventory and status of private and public drinking water wells in the immediate vicinity of the former CCC/USDA grain storage facility, and sample the identified wells for volatile organic compounds (VOCs) and geochemical analyses. In conjunction with this effort, determine the present sources(s) of drinking water for all residents in an approximate 0.5-mi radius of the former CCC/USDA facility. 2. Investigate for possible evidence of a soil source of carbon tetrachloride contamination in the unconsolidated sediments beneath the former CCC/USDA facility that might affect the underlying bedrock aquifer units. 3. Obtain preliminary information on the site-specific lithologic and hydrologic characteristics of the unconsolidated sediments overlying bedrock at the former CCC/USDA grain storage location. Section 2 of

Brightness analysis of an electron beam with a complex profile

NASA Astrophysics Data System (ADS)

Maesaka, Hirokazu; Hara, Toru; Togawa, Kazuaki; Inagaki, Takahiro; Tanaka, Hitoshi

2018-05-01

We propose a novel analysis method to obtain the core bright part of an electron beam with a complex phase-space profile. This method is beneficial to evaluate the performance of simulation data of a linear accelerator (linac), such as an x-ray free electron laser (XFEL) machine, since the phase-space distribution of a linac electron beam is not simple, compared to a Gaussian beam in a synchrotron. In this analysis, the brightness of undulator radiation is calculated and the core of an electron beam is determined by maximizing the brightness. We successfully extracted core electrons from a complex beam profile of XFEL simulation data, which was not expressed by a set of slice parameters. FEL simulations showed that the FEL intensity was well remained even after extracting the core part. Consequently, the FEL performance can be estimated by this analysis without time-consuming FEL simulations.

The status and road map of Turkish Accelerator Center (TAC)

NASA Astrophysics Data System (ADS)

Yavaş, Ö.

2012-02-01

Turkish Accelerator Center (TAC) project is supported by the State Planning Organization (SPO) of Turkey and coordinated by Ankara University. After having completed the Feasibility Report (FR) in 2000 and the Conceptual Design Report (CDR) in 2005, third phase of the project started in 2006 as an inter-universities project including ten Turkish Universities with the support of SPO. Third phase of the project has two main scientific goals: to prepare the Technical Design Report (TDR) of TAC and to establish an Infrared Free Electron Laser (IR FEL) facility, named as Turkish Accelerator and Radiation Laboratory at Ankara (TARLA) as a first step. The facility is planned to be completed in 2015 and will be based on 15-40 MeV superconducting linac. In this paper, main aims, national and regional importance, main parts main parameters, status and road map of Turkish Accelerator Center will be presented.

Facile Aqueous Phase Synthesis of Pd3Cu-B/C Nanocatalyst for Glucose Electrooxidation

NASA Astrophysics Data System (ADS)

Chai, Dan; Lu, Haibin; Wang, Yaqian; Hua, Xiuwen; Ren, Na; Zhang, Xiongwen

2018-01-01

A novel Pd3Cu-B/C nanocatalyst was facilely synthesized through an aqueous phase process. And it was developed for use in the glucose electrooxidation reaction in fuel cells. Cyclic voltammetry shown that the electrochemical surface area of Pd3Cu-B/C is 2.25 times that of Pd/C. Glucose electrooxidation curves revealed that peak current on the Pd3Cu-B/C is actually 1.73 times of the Pd/C. This high performance of Pd3Cu-B/C could be ascribed to the synergistic effect between Pd, Cu and B.

Marshak Lectureship: The Turkish Accelerator Center, TAC

NASA Astrophysics Data System (ADS)

Yavas, Omer

2012-02-01

The Turkish Accelerator Center (TAC) project is comprised of five different electron and proton accelerator complexes, to be built over 15 years, with a phased approach. The Turkish Government funds the project. Currently there are 23 Universities in Turkey associated with the TAC project. The current funded project, which is to run until 2013 aims *To establish a superconducting linac based infra-red free electron laser and Bremsstrahlung Facility (TARLA) at the Golbasi Campus of Ankara University, *To establish the Institute of Accelerator Technologies in Ankara University, and *To complete the Technical Design Report of TAC. The proposed facilities are a 3^rd generation Synchrotron Radiation facility, SASE-FEL facility, a GeV scale Proton Accelerator facility and an electron-positron collider as a super charm factory. In this talk, an overview on the general status and road map of TAC project will be given. National and regional importance of TAC will be expressed and the structure of national and internatonal collaborations will be explained.

MITHRA 1.0: A full-wave simulation tool for free electron lasers

NASA Astrophysics Data System (ADS)

Fallahi, Arya; Yahaghi, Alireza; Kärtner, Franz X.

2018-07-01

Free Electron Lasers (FELs) are a solution for providing intense, coherent and bright radiation in the hard X-ray regime. Due to the low wall-plug efficiency of FEL facilities, it is crucial and additionally very useful to develop complete and accurate simulation tools for better optimizing a FEL interaction. The highly sophisticated dynamics involved in a FEL process was the main obstacle hindering the development of general simulation tools for this problem. We present a numerical algorithm based on finite difference time domain/Particle in cell (FDTD/PIC) in a Lorentz boosted coordinate system which is able to fulfill a full-wave simulation of a FEL process. The developed software offers a suitable tool for the analysis of FEL interactions without considering any of the usual approximations. A coordinate transformation to bunch rest frame makes the very different length scales of bunch size, optical wavelengths and the undulator period transform to values with the same order. Consequently, FDTD/PIC simulations in conjunction with efficient parallelization techniques make the full-wave simulation feasible using the available computational resources. Several examples of free electron lasers are analyzed using the developed software, the results are benchmarked based on standard FEL codes and discussed in detail.

Assessment of the Vapor Phase Catalytic Ammonia Removal (VPCAR) Technology at the MSFC ECLS Test Facility

NASA Technical Reports Server (NTRS)

Tomes, Kristin; Long, David; Carter, Layne; Flynn, Michael

2007-01-01

The Vapor Phase Catalytic Ammonia. Removal (VPCAR) technology has been previously discussed as a viable option for. the Exploration Water Recovery System. This technology integrates a phase change process with catalytic oxidation in the vapor phase to produce potable water from exploration mission wastewaters. A developmental prototype VPCAR was designed, built and tested under funding provided by a National Research. Announcement (NRA) project. The core technology, a Wiped Film Rotating Device (WFRD) was provided by Water Reuse Technologies under the NRA, whereas Hamilton Sundstrand Space Systems International performed the hardware integration and acceptance test. of the system. Personnel at the-Ames Research Center performed initial systems test of the VPCAR using ersatz solutions. To assess the viability of this hardware for Exploration. Life Support (ELS) applications, the hardware has been modified and tested at the MSFC ECLS Test facility. This paper summarizes the hardware modifications and test results and provides an assessment of this technology for the ELS application.

National Facilities study

NASA Technical Reports Server (NTRS)

1994-01-01

This study provides a set of recommendations for improving the effectiveness of our nation's aeronautics and space facilities. The study plan considers current and future government and commercial needs as well as DOD and NASA mission requirements through the year 2023. It addresses shortfalls in existing capabilities, new facility requirements, upgrades, consolidations, and phase-out of existing facilities. If the recommendations are implemented, they will provide world-class capability where it is vital to our country's needs and make us more efficient in meeting future needs.

Roadmap to MaRIE March 2015

DOE Office of Scientific and Technical Information (OSTI.GOV)

Barnes, Cris William

Los Alamos National Laboratory’s proposed MaRIE facility is slated to introduce the world’s highest energy hard x-ray free electron laser (XFEL). As the light source for the Matter-Radiation Interactions in Extremes experimental facility (MaRIE), the 42-keV XFEL, with bursts of x-ray pulses at gigahertz repetition for studying fast dynamical processes, will help accelerate discovery and design of the advanced materials needed to meet 21st-century national security and energy security challenges. Yet the science of free-electron lasers has a long and distinguished history at Los Alamos National Laboratory (LANL), where for nearly four decades Los Alamos scientists have been performing research,more » design, development, and collaboration work in FEL science. The work at Los Alamos has evolved from low-gain amplifier and oscillator FEL development to highbrightness photoinjector development, and later, self-amplified spontaneous emission (SASE) and high-gain amplifier FEL development.« less

Floor vibration evaluations for medical facilities

NASA Astrophysics Data System (ADS)

Himmel, Chad N.

2003-10-01

The structural floor design for new medical facilities is often selected early in the design phase and in renovation projects, the floor structure already exists. Because the floor structure can often have an influence on the location of vibration sensitive medical equipment and facilities, it is becoming necessary to identify the best locations for equipment and facilities early in the design process. Even though specific criteria for vibration-sensitive uses and equipment may not always be available early in the design phase, it should be possible to determine compatible floor structures for planned vibration-sensitive uses by comparing conceptual layouts with generic floor vibration criteria. Relatively simple evaluations of planned uses and generic criteria, combined with on-site vibration and noise measurements early in design phase, can significantly reduce future design problems and expense. Concepts of evaluation procedures and analyses will be presented in this paper. Generic floor vibration criteria and appropriate parameters to control resonant floor vibration and noise will be discussed for typical medical facilities and medical research facilities. Physical, economic, and logistical limitations that affect implementation will be discussed through case studies.

Sub-micron resolution rf cavity beam position monitor system at the SACLA XFEL facility

NASA Astrophysics Data System (ADS)

Maesaka, H.; Ego, H.; Inoue, S.; Matsubara, S.; Ohshima, T.; Shintake, T.; Otake, Y.

2012-12-01

We have developed and constructed a C-band (4.760 GHz) rf cavity beam position monitor (RF-BPM) system for the XFEL facility at SPring-8, SACLA. The demanded position resolution of the RF-BPM is less than 1 μm, because an electron beam and x-rays must be overlapped within 4 μm precision in the undulator section for sufficient FEL interaction between the electrons and x-rays. In total, 57 RF-BPMs, including IQ demodulators and high-speed waveform digitizers for signal processing, were produced and installed into SACLA. We evaluated the position resolutions of 20 RF-BPMs in the undulator section by using a 7 GeV electron beam having a 0.1 nC bunch charge. The position resolution was measured to be less than 0.6 μm, which was sufficient for the XFEL lasing in the wavelength region of 0.1 nm, or shorter.

The DarkLight Experiment at the JLab FEL

NASA Astrophysics Data System (ADS)

Fisher, Peter

2013-10-01

DarkLight will study the production of gauge bosons associated with Dark Forces theories in the scattering of 100 MeV electrons on proton a target. DarkLight is a spectrometer to measure all the final state particles in e- + p -->e- + p +e- +e+ . QED allows this process and the invariant mass distribution of the e+e- pair is a continuum from nearly zero to nearly the electron beam energy. Dark Forces theories, which allow the dark matter mass scale to be over 1 TeV, predict a gauge boson A' in the mass range of 10-1,000 MeV and decays to an electron-positron pair with an invariant mass of mA'. We aim to search for this process using the 100 MeV, 10 mA electron beam at the JLab Free Electron Laser impinging on a hydrogen target with a 1019 cm-2 density. The resulting luminosity of 6 ×1035/cm2-s gives the experiment enough sensitivity to probe A' couplings of 10-9 α . DarkLight is unique in its design to detect all four particles in the final state. The leptons will be measured in a large high-rate TPC and a silicon sensor will measure the protons. A 0.5 T solenoidal magnetic field provides the momentum resolution and focuses the copious Møller scattering background down the beam line, away from the detectors. A first beam test has shown the FEL beam is compatible with the target design and that the hall backgrounds are manageable. The experiment has been approved by Jefferson Lab for first running in 2017.

How women are treated during facility-based childbirth: development and validation of measurement tools in four countries - phase 1 formative research study protocol.

PubMed

Vogel, Joshua P; Bohren, Meghan A; Tunçalp, Özge; Oladapo, Olufemi T; Adanu, Richard M; Baldé, Mamadou Diouldé; Maung, Thae Maung; Fawole, Bukola; Adu-Bonsaffoh, Kwame; Dako-Gyeke, Phyllis; Maya, Ernest Tei; Camara, Mohamed Campell; Diallo, Alfa Boubacar; Diallo, Safiatou; Wai, Khin Thet; Myint, Theingi; Olutayo, Lanre; Titiloye, Musibau; Alu, Frank; Idris, Hadiza; Gülmezoglu, Metin A

2015-07-22

Every woman has the right to dignified, respectful care during childbirth. Recent evidence has demonstrated that globally many women experience mistreatment during labour and childbirth in health facilities, which can pose a significant barrier to women attending facilities for delivery and can contribute to poor birth experiences and adverse outcomes for women and newborns. However there is no clear consensus on how mistreatment of women during childbirth in facilities is defined and measured. We propose using a two-phased, mixed-methods study design in four countries to address these research gaps. This protocol describes the Phase 1 qualitative research activities. We will employ qualitative research methodologies among women, healthcare providers and administrators in the facility catchment areas of two health facilities in each country: Ghana, Guinea, Myanmar and Nigeria. In-depth interviews (IDIs) and focus group discussions (FGDs) will be conducted among women of reproductive age (15-49 years) to explore their perceptions and experiences of facility-based childbirth care, focused on how they were treated by healthcare workers and perceived factors affecting how they were treated. IDIs will also be conducted with healthcare providers of different cadres (e.g.: nurses, midwives, medical officers, specialist obstetricians) and facility administrators working in the selected facilities to explore healthcare providers' perceptions and experiences of facility-based childbirth care and how staff are treated, colleagues and supervisors. Audio recordings will be transcribed and translated to English. Textual data will be analysed using a thematic framework approach and will consist of two levels of analysis: (1) conduct of local analysis workshops with the research assistants in each country; and (2) line-by-line coding to develop a thematic framework and coding scheme. This study serves several roles. It will provide an in-depth understanding of how women are

Final work plan : Phase I investigation of potential contamination at the former CCC/USDA grain storage facility in Savannah, Missouri.

DOE Office of Scientific and Technical Information (OSTI.GOV)

LaFreniere, L. M.; Environmental Science Division

contamination. This work will be performed in accord with the Intergovernmental Agreement established between the Farm Service Agency of the USDA and MoDNR, to address carbon tetrachloride contamination potentially associated with a number of former CCC/USDA grain storage facilities in Missouri. The investigative activities at Savannah will be conducted on behalf of the CCC/USDA by the Environmental Science Division of Argonne National Laboratory. Argonne is a nonprofit, multidisciplinary research center operated by UChicago Argonne, LLC, for the U.S. Department of Energy (DOE). The CCC/USDA has entered into an agreement with the DOE, under which Argonne provides technical assistance to the CCC/USDA with environmental site characterization and remediation at its former grain storage facilities. The site characterization at Savannah will take place in phases. This approach is recommended by the CCC/USDA and Argonne, so that information obtained and interpretations developed during each incremental stage of the investigation can be used most effectively to guide subsequent phases of the program. This site-specific Work Plan outlines the specific technical objectives and scope of work proposed for Phase I of the Savannah investigation. This Work Plan also includes the community relations plan to be followed throughout the CCC/USDA program at the Savannah site. Argonne is developing a Master Work Plan specific to operations in the state of Missouri. In the meantime, Argonne will issue a Provisional Master Work Plan (PMWP; Argonne 2007) that will be submitted to the MoDNR for review and approval. The agency has already reviewed and approved (with minor changes) the present Master Work Plan (Argonne 2002) under which Argonne currently operates in Kansas. The PMWP (Argonne 2007) will provide detailed information and guidance on the investigative technologies, analytical methodologies, quality assurance-quality control measures, and general health and safety policies to be employed by

Bunching phase and constraints on echo enabled harmonic generation

NASA Astrophysics Data System (ADS)

Hemsing, E.

2018-05-01

A simple mathematical description is developed for the bunching spectrum in echo enabled harmonic generation (EEHG) that incorporates the effect of additional electron beam energy modulations. Under common assumptions, they are shown to contribute purely through the phase of the longitudinal bunching factor, which allows the spectral moments of the bunching to be calculated directly from the known energy modulations. In particular, the second moment (spectral bandwidth) serves as simple constraint on the amplitude of the energy modulations to maintain a transform-limited seed. We show that, in general, the impact on the spectrum of energy distortions that develop between the EEHG chicanes scales like the harmonic number compared to distortions that occur upstream. This may limit the parameters that will allow EEHG to reach short wavelengths in high brightness FELs.

National Synchrotron Light Source annual report 1991. Volume 1, October 1, 1990--September 30, 1991

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hulbert, S.L.; Lazarz, N.M.

1992-04-01

This report discusses the following research conducted at NSLS: atomic and molecular science; energy dispersive diffraction; lithography, microscopy and tomography; nuclear physics; UV photoemission and surface science; x-ray absorption spectroscopy; x-ray scattering and crystallography; x-ray topography; workshop on surface structure; workshop on electronic and chemical phenomena at surfaces; workshop on imaging; UV FEL machine reviews; VUV machine operations; VUV beamline operations; VUV storage ring parameters; x-ray machine operations; x-ray beamline operations; x-ray storage ring parameters; superconducting x-ray lithography source; SXLS storage ring parameters; the accelerator test facility; proposed UV-FEL user facility at the NSLS; global orbit feedback systems; and NSLSmore » computer system.« less

National Synchrotron Light Source annual report 1991

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hulbert, S.L.; Lazarz, N.M.

1992-04-01

This report discusses the following research conducted at NSLS: atomic and molecular science; energy dispersive diffraction; lithography, microscopy and tomography; nuclear physics; UV photoemission and surface science; x-ray absorption spectroscopy; x-ray scattering and crystallography; x-ray topography; workshop on surface structure; workshop on electronic and chemical phenomena at surfaces; workshop on imaging; UV FEL machine reviews; VUV machine operations; VUV beamline operations; VUV storage ring parameters; x-ray machine operations; x-ray beamline operations; x-ray storage ring parameters; superconducting x-ray lithography source; SXLS storage ring parameters; the accelerator test facility; proposed UV-FEL user facility at the NSLS; global orbit feedback systems; and NSLSmore » computer system.« less

Design of compressors for FEL pulses using deformable gratings

NASA Astrophysics Data System (ADS)

Bonora, Stefano; Fabris, Nicola; Frassetto, Fabio; Giovine, Ennio; Miotti, Paolo; Quintavalla, Martino; Poletto, Luca

2017-06-01

We present the optical layout of soft X-rays compressors using reflective grating specifically designed to give both positive or negative group-delay dispersion (GDD). They are tailored for chirped-pulse-amplification experiments with FEL sources. The optical design originates from an existing compressor with plane gratings already realized and tested at FERMI, that has been demonstrated capable to introduce tunable negative GDD. Here, we discuss two novel designs for compressors using deformable gratings capable to give both negative and positive GDD. Two novel designs are discussed: 1) a design with two deformable gratings and an intermediate focus between the twos, that is demonstrated capable to introduce positive GDD; 2) a design with one deformable grating giving an intermediate focus, followed by a concave mirror and a plane grating, that is capable to give both positive and negative GDD depending on the distance between the second mirror and the second grating. Both the designs are tunable in wavelength and GDD, by acting on the deformable gratings, that are rotated to tune the wavelength and the GDD and deformed to introduce the radius required to keep the spectral focus. The deformable gratings have a laminar profile and are ruled on a thin silicon plane substrate. A piezoelectric actuator is glued on the back of the substrate and is actuated to give a radius of curvature that is varying from infinite (plane) to few meters. The ruling procedure, the piezoelectric actuator and the efficiency measurements in the soft X-rays will be presented. Some test cases are discussed for wavelengths shorter than 12 nm.

A negative ion source test facility

NASA Astrophysics Data System (ADS)

Melanson, S.; Dehnel, M.; Potkins, D.; Theroux, J.; Hollinger, C.; Martin, J.; Philpott, C.; Stewart, T.; Jackle, P.; Williams, P.; Brown, S.; Jones, T.; Coad, B.; Withington, S.

2016-02-01

Progress is being made in the development of an Ion Source Test Facility (ISTF) by D-Pace Inc. in collaboration with Buckley Systems Ltd. in Auckland, NZ. The first phase of the ISTF is to be commissioned in October 2015 with the second phase being commissioned in March 2016. The facility will primarily be used for the development and the commercialization of ion sources. It will also be used to characterize and further develop various D-Pace Inc. beam diagnostic devices.

The Next Phase.

ERIC Educational Resources Information Center

Oualline, John; Rabenaldt, Carl

2002-01-01

Discusses how phased facility assessments, rather than one comprehensive assessment, may be an answer to identifying and addressing capital renewal and deferred maintenance. Presents a table outlining the facility assessment levels and attendant measurement methods. (EV)

Solid-phase microextraction of organophosphate pesticides in source waters for drinking water treatment facilities.

PubMed

Flynt, Elizabeth; Dupuy, Aubry; Kennedy, Charles; Bennett, Shanda

2006-09-01

The rapid detection of contaminants in our nation's drinking water has become a top homeland security priority in this time of increased national vigilance. Real-time monitoring of drinking water for deliberate or accidental contamination is key to national security. One method that can be employed for the rapid screening of pollutants in water is solid-phase microextraction (SPME). SPME is a rapid, sensitive, solvent-free system that can be used to screen for contaminants that have been accidentally or intentionally introduced into a water system. A method using SPME has been developed and optimized for the detection of seven organophosphate pesticides in drinking water treatment facility source waters. The method is tested in source waters for drinking water treatment facilities in Mississippi and Alabama. Water is collected from a deepwater well at Stennis Space Center (SSC), MS, the drinking water source for SSC, and from the Converse Reservoir, the main drinking water supply for Mobile, AL. Also tested are samples of water collected from the Mobile Alabama Water and Sewer System drinking water treatment plant prior to chlorination. The method limits of detection for the seven organophosphates were comparable to those described in several Environmental Protection Agency standard methods. They range from 0.25 to 0.94 microg/L.

A theory for optical wavelength control in short pulse free electron laser oscillators

NASA Astrophysics Data System (ADS)

Wilkenson, Wade F.

1993-06-01

The future safety of the U.S. Navy warship depends on the development of a directed energy self-defense system to keep pace with the ever-improving technology of anti-ship missiles. Two candidates are reviewed. The free electron laser (FEL) has the most advantages, but a chemical laser proposed by TRW is ready for installation on existing ships. Initial testing of issues related to directed energy use at sea can be conducted with the chemical laser. When the technology of the FEL matures, it can replace the chemical laser to provide the best possible defense in the shortest period of time. Continuous tunability is a key advantage of the FEL over the conventional laser. But since the output wavelength is dependent on electron energy, it is subject to random fluctuations originating from the beam source. At the Stanford University Superconducting (SCA) Free Electron Laser (FEL) Facility, the effects are minimized through negative feedback by changing the input electron energy proportional to the observed wavelength drift. The process is simulated by modifying a short pulse FEL numerical program to allow the resonant wavelength to vary over many passes. The physical effects behind optical wavelength control are explained. A theory for the preferential nature of the FEL to follow the resonant wavelength from longer to shorter wavelengths is presented. Finally, the response of the FEL to a rapidly changing resonant wavelength is displayed as a transfer function for the system.

Final work plan : phase I investigation of potential contamination at the former CCC/USDA grain storage facility in Montgomery City, Missouri.

DOE Office of Scientific and Technical Information (OSTI.GOV)

LaFreniere, L. M.; Environmental Science Division

at its former grain storage facility, the CCC/USDA will conduct investigations to (1) characterize the source(s), extent, and factors controlling the possible subsurface distribution and movement of carbon tetrachloride at the Montgomery City site and (2) evaluate the health and environmental threats potentially represented by the contamination. This work will be performed in accord with the Intergovernmental Agreement established between the Farm Service Agency of the USDA and the MoDNR, to address carbon tetrachloride contamination potentially associated with a number of former CCC/USDA grain storage facilities in Missouri. The investigations at Montgomery City will be conducted on behalf of the CCC/USDA by the Environmental Science Division of Argonne National Laboratory. Argonne is a nonprofit, multidisciplinary research center operated by UChicago Argonne, LLC, for the U.S. Department of Energy (DOE). The CCC/USDA has entered into an agreement with DOE, under which Argonne provides technical assistance to the CCC/USDA with environmental site characterization and remediation at its former grain storage facilities. The site characterization at Montgomery City will take place in phases. This approach is recommended by the CCC/USDA and Argonne, so that information obtained and interpretations developed during each incremental stage of the investigation can be used most effectively to guide subsequent phases of the program. This site-specific Work Plan outlines the specific technical objectives and scope of work proposed for Phase I of the Montgomery City investigation. This Work Plan also includes the community relations plan to be followed throughout the CCC/USDA program at the Montgomery City site. Argonne is developing a Master Work Plan specific to operations in the state of Missouri. In the meantime, Argonne has issued a Provisional Master Work Plan (PMWP; Argonne 2007) that has been reviewed and approved by the MoDNR for current use. The PMWP (Argonne 2007

A High-Average-Power Free Electron Laser for Microfabrication and Surface Applications

NASA Technical Reports Server (NTRS)

Dylla, H. F.; Benson, S.; Bisognano, J.; Bohn, C. L.; Cardman, L.; Engwall, D.; Fugitt, J.; Jordan, K.; Kehne, D.; Li, Z.;

Statistical properties of radiation from VUV and X-ray free electron laser

NASA Astrophysics Data System (ADS)

Saldin, E. L.; Schneidmiller, E. A.; Yurkov, M. V.

1998-03-01

The paper presents a comprehensive analysis of the statistical properties of the radiation from a self-amplified spontaneous emission (SASE) free electron laser operating in linear and nonlinear mode. The investigation has been performed in a one-dimensional approximation assuming the electron pulse length to be much larger than a coherence length of the radiation. The following statistical properties of the SASE FEL radiation have been studied in detail: time and spectral field correlations, distribution of the fluctuations of the instantaneous radiation power, distribution of the energy in the electron bunch, distribution of the radiation energy after the monochromator installed at the FEL amplifier exit and radiation spectrum. The linear high gain limit is studied analytically. It is shown that the radiation from a SASE FEL operating in the linear regime possesses all the features corresponding to completely chaotic polarized radiation. A detailed study of statistical properties of the radiation from a SASE FEL operating in linear and nonlinear regime has been performed by means of time-dependent simulation codes. All numerical results presented in the paper have been calculated for the 70 nm SASE FEL at the TESLA Test Facility being under construction at DESY.

SLUDGE TREATMENT PROJECT PHASE 1 SLUDGE STORAGE OPTIONS ASSESSMENT OF T PLANT VERSUS ALTERNATE STORAGE FACILITY

DOE Office of Scientific and Technical Information (OSTI.GOV)

RUTHERFORD WW; GEUTHER WJ; STRANKMAN MR

2009-04-29

The CH2M HILL Plateau Remediation Company (CHPRC) has recommended to the U.S. Department of Energy (DOE) a two phase approach for removal and storage (Phase 1) and treatment and packaging for offsite shipment (Phase 2) of the sludge currently stored within the 105-K West Basin. This two phased strategy enables early removal of sludge from the 105-K West Basin by 2015, allowing remediation of historical unplanned releases of waste and closure of the 100-K Area. In Phase 1, the sludge currently stored in the Engineered Containers and Settler Tanks within the 105-K West Basin will be transferred into sludge transportmore » and storage containers (STSCs). The STSCs will be transported to an interim storage facility. In Phase 2, sludge will be processed (treated) to meet shipping and disposal requirements and the sludge will be packaged for final disposal at a geologic repository. The purpose of this study is to evaluate two alternatives for interim Phase 1 storage of K Basin sludge. The cost, schedule, and risks for sludge storage at a newly-constructed Alternate Storage Facility (ASF) are compared to those at T Plant, which has been used previously for sludge storage. Based on the results of the assessment, T Plant is recommended for Phase 1 interim storage of sludge. Key elements that support this recommendation are the following: (1) T Plant has a proven process for storing sludge; (2) T Plant storage can be implemented at a lower incremental cost than the ASF; and (3) T Plant storage has a more favorable schedule profile, which provides more float, than the ASF. Underpinning the recommendation of T Plant for sludge storage is the assumption that T Plant has a durable, extended mission independent of the K Basin sludge interim storage mission. If this assumption cannot be validated and the operating costs of T Plant are borne by the Sludge Treatment Project, the conclusions and recommendations of this study would change. The following decision-making strategy

A similarity score-based two-phase heuristic approach to solve the dynamic cellular facility layout for manufacturing systems

NASA Astrophysics Data System (ADS)

Kumar, Ravi; Singh, Surya Prakash

2017-11-01

The dynamic cellular facility layout problem (DCFLP) is a well-known NP-hard problem. It has been estimated that the efficient design of DCFLP reduces the manufacturing cost of products by maintaining the minimum material flow among all machines in all cells, as the material flow contributes around 10-30% of the total product cost. However, being NP hard, solving the DCFLP optimally is very difficult in reasonable time. Therefore, this article proposes a novel similarity score-based two-phase heuristic approach to solve the DCFLP optimally considering multiple products in multiple times to be manufactured in the manufacturing layout. In the first phase of the proposed heuristic, a machine-cell cluster is created based on similarity scores between machines. This is provided as an input to the second phase to minimize inter/intracell material handling costs and rearrangement costs over the entire planning period. The solution methodology of the proposed approach is demonstrated. To show the efficiency of the two-phase heuristic approach, 21 instances are generated and solved using the optimization software package LINGO. The results show that the proposed approach can optimally solve the DCFLP in reasonable time.

Electric power generation using geothermal brine resources for a proof of concept facility

NASA Technical Reports Server (NTRS)

Hankin, J. W.

1974-01-01

An exploratory systems study of a geothermal proof-of-concept facility is being conducted. This study is the initial phase (Phase 0) of a project to establish the technical and economic feasibility of using hot brine resources for electric power production and other industrial applications. Phase 0 includes the conceptual design of an experimental test-bed facility and a 10-MWe power generating facility.

Operational Phase Life Cycle Assessment of Select NASA Ground Test Facilities

NASA Technical Reports Server (NTRS)

Sydnor, George H.; Marshall, Timothy J.; McGinnis, Sean

2011-01-01

NASA's Aeronautics Test Program (ATP) is responsible for many large, high-energy ground test facilities that accomplish the nation s most advanced aerospace research. In order to accomplish these national objectives, significant energy and resources are consumed. A select group of facilities was analyzed using life-cycle assessment (LCA) to determine carbon footprint and environmental impacts. Most of these impacts stem from electricity and natural gas consumption, used directly at the facility and to generate support processes such as compressed air and steam. Other activities were analyzed but determined to be smaller in scale and frequency with relatively negligible environmental impacts. More specialized facilities use R-134a, R-14, jet fuels, or nitrogen gas, and these unique inputs can have a considerable effect on a facility s overall environmental impact. The results of this LCA will be useful to ATP and NASA as the nation looks to identify its top energy consumers and NASA looks to maximize research output and minimize environmental impact. Keywords: NASA, Aeronautics, Wind tunnel, Keyword 4, Keyword 5

Wavefront correction by target-phase-locking technology in a 500 TW laser facility

NASA Astrophysics Data System (ADS)

Wang, D. E.; Dai, W. J.; Zhou, K. N.; Su, J. Q.; Xue, Q.; Yuan, Q.; Zhang, X.; Deng, X. W.; Yang, Y.; Wang, Y. C.; Xie, N.; Sun, L.; Hu, D. X.; Zhu, Q. H.

2017-03-01

We demonstrate a novel approach termed target-phase-locking that could improve the entire beam wavefront quality of a 500 TW Nd3+:phosphate glass laser facility. The thermal and static wavefront from front-end to target is corrected by using one deformable mirror that receives feedback from both the focal-spot sensor and wavefront sensor, and only the main laser of the laser system is employed in the correction process, with auxiliary calibration light no longer necessary. As a result, a static focal spot with full width at half maximum of 8.87  ×  5.74 µm is achieved, the thermal wavefront induced by flash-lamp-pumped Nd3+:phosphate glass is compensated with PV from 3.54-0.43 µm, and a dynamic focal spot with intensity exceeding 1020 W cm-2 is precisely predicted at the target with such an approach.

Beam-Dynamics Analysis of Long-Range Wakefield Effects on the SCRF Cavities at the Fast Facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shin, Young-Min; Bishofberger, Kip; Carlsten, Bruce

Long-range wakefields in superconducting RF (SCRF) cavities create complicated effects on beam dynamics in SCRF-based FEL beamlines. The driving bunch excites effectively an infinite number of structure modes (including HOMs) which oscillate within the SCRF cavity. Couplers with loads are used to damp the HOMs. However, these HOMs can persist for long periods of time in superconducting structures, which leads to long-range wakefields. Clear understanding of the long-range wakefield effects is a critical element for risk mitigation of future SCRF accelerators such as XFEL at DESY, LCLS-II XFEL, and MaRIE XFEL. We are currently developing numerical tools for simulating long-rangemore » wakefields in SCRF accelerators and plan to experimentally verify the tools by measuring these wakefields at the Fermilab Accelerator Science and Technology (FAST) facility. This paper previews the experimental conditions at the FAST 50 MeV beamline based on the simulation results.« less

Identification and Quantification of Carbon Phases in Conversion Fuel for the Transient Reactor Test Facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Steele, Robert; Mata, Angelica; Dunzik-Gougar, Mary Lou

2016-06-01

As part of an overall effort to convert US research reactors to low-enriched uranium (LEU) fuel use, a LEU conversion fuel is being designed for the Transient Reactor Test Facility (TREAT) at the Idaho National Laboratory. TREAT fuel compacts are comprised of UO2 fuel particles in a graphitic matrix material. In order to refine heat transfer modeling, as well as determine other physical and nuclear characteristics of the fuel, the amount and type of graphite and non-graphite phases within the fuel matrix must be known. In this study, we performed a series of complementary analyses, designed to allow detailed characterizationmore » of the graphite and phenolic resin based fuel matrix. Methods included Scanning Electron and Transmission Electron Microscopies, Raman spectroscopy, X-ray Diffraction, and Dual-Beam Focused Ion Beam Tomography. Our results indicate that no single characterization technique will yield all of the desired information; however, through the use of statistical and empirical data analysis, such as curve fitting, partial least squares regression, volume extrapolation and spectra peak ratios, a degree of certainty for the quantity of each phase can be obtained.« less

Coherence properties of the radiation from FLASH

NASA Astrophysics Data System (ADS)

Schneidmiller, E. A.; Yurkov, M. V.

2016-02-01

Free electron LASer in Hamburg is the first free electron laser user facility operating in the vacuum ultraviolet and soft X-ray wavelength range. Many user experiments require knowledge of the spatial and temporal coherence properties of the radiation. In this paper, we present a theoretical analysis of the coherence properties of the radiation for the fundamental and for the higher odd frequency harmonics. We show that temporal and spatial coherence reach their maxima close to the free electron laser (FEL) saturation but may degrade significantly in the post-saturation regime. We also find that the pointing stability of short FEL pulses is limited due to the fact that nonazimuthal FEL eigenmodes are not sufficiently suppressed. We discuss possible ways for improving the degree of transverse coherence and the pointing stability.

Analysis of multibunch free electron laser operation

NASA Astrophysics Data System (ADS)

Hellert, Thorsten; Decking, Winfried; Branlard, Julien

2017-09-01

At the SASE-FEL user facilities FLASH and European XFEL, superconducting TESLA type cavities are used for acceleration of the driving electron bunches. The high achievable duty cycle allows for operating with long bunch trains, hence considerably increasing the efficiency of the machine. However, multibunch free electron lasers (FEL) operation requires longitudinal and transverse stability within the bunch train. The purpose of this work is to investigate the intra-bunch-train transverse dynamics at FLASH and European XFEL. Key relationships of superconducting rf cavity operation and the resulting impact on the intrabunch-train trajectory variation are described. The observed trajectory variation during multibunch user runs at FLASH is analyzed and related to both, intrabunch-train variations of the rf and the following impact on the multibunch FEL performance.

South Yorkshire Cohort: a 'cohort trials facility' study of health and weight - protocol for the recruitment phase.

PubMed

Relton, Clare; Bissell, Paul; Smith, Christine; Blackburn, Joanna; Cooper, Cindy L; Nicholl, Jon; Tod, Angela; Copeland, Rob; Loban, Amanda; Chater, Tim; Thomas, Kate; Young, Tracy; Weir, Carol; Harrison, Gill; Millbourn, Alison; Manners, Rachel

2011-08-11

Growing levels of both obesity and chronic disease in the general population pose a major public health problem. In the UK, an innovative 'health and weight' cohort trials facility, the 'South Yorkshire Cohort', is being built in order to provide robust evidence to inform policy, commissioning and clinical decisions in this field. This protocol reports the design of the facility and outlines the recruitment phase methods. The South Yorkshire Cohort health and weight study uses the cohort multiple randomised controlled trial design. This design recruits a large observational cohort of patients with the condition(s) of interest which then provides a facility for multiple randomised controlled trials (with large representative samples of participants, long term outcomes as standard, increased comparability between each trial conducted within the cohort and increased efficiency particularly for trials of expensive interventions) as well as ongoing information as to the natural history of the condition and treatment as usual.This study aims to recruit 20,000 participants to the population based South Yorkshire Cohort health and weight research trials facility. Participants are recruited by invitation letters from their General Practitioners. Data is collected using postal and/or online patient self completed Health Questionnaires. NHS numbers will be used to facilitate record linkage and access to routine data. Participants are eligible if they are: aged 16 - 85 years, registered with one of 40 practices in South Yorkshire, provide consent for further contact from the researchers and to have their information used to look at the benefit of health treatments. The first wave of data is being collected during 2010/12 and further waves are planned at 2 - 5 year intervals for the planned 20 year duration of the facility. The South Yorkshire Cohort combines the strengths of the standard observational, longitudinal cohort study design with a population based cohort facility

South Yorkshire Cohort: a 'cohort trials facility' study of health and weight - Protocol for the recruitment phase

PubMed Central

2011-01-01

Background Growing levels of both obesity and chronic disease in the general population pose a major public health problem. In the UK, an innovative 'health and weight' cohort trials facility, the 'South Yorkshire Cohort', is being built in order to provide robust evidence to inform policy, commissioning and clinical decisions in this field. This protocol reports the design of the facility and outlines the recruitment phase methods. Method/Design The South Yorkshire Cohort health and weight study uses the cohort multiple randomised controlled trial design. This design recruits a large observational cohort of patients with the condition(s) of interest which then provides a facility for multiple randomised controlled trials (with large representative samples of participants, long term outcomes as standard, increased comparability between each trial conducted within the cohort and increased efficiency particularly for trials of expensive interventions) as well as ongoing information as to the natural history of the condition and treatment as usual. This study aims to recruit 20,000 participants to the population based South Yorkshire Cohort health and weight research trials facility. Participants are recruited by invitation letters from their General Practitioners. Data is collected using postal and/or online patient self completed Health Questionnaires. NHS numbers will be used to facilitate record linkage and access to routine data. Participants are eligible if they are: aged 16 - 85 years, registered with one of 40 practices in South Yorkshire, provide consent for further contact from the researchers and to have their information used to look at the benefit of health treatments. The first wave of data is being collected during 2010/12 and further waves are planned at 2 - 5 year intervals for the planned 20 year duration of the facility. Discussion The South Yorkshire Cohort combines the strengths of the standard observational, longitudinal cohort study design with

Characterization of exposure to silver nanoparticles in a manufacturing facility

NASA Astrophysics Data System (ADS)

Park, Junsu; Kwak, Byoung Kyu; Bae, Eunjoo; Lee, Jeongjin; Kim, Younghun; Choi, Kyunghee; Yi, Jongheop

2009-10-01

An assessment of the extent of exposure to nanomaterials in the workplace will be helpful in improving the occupational safety of workers. It is essential that the exposure data in the workplace are concerned with risk management to evaluate and reduce worker exposure. In a manufacturing facility dealing with nanomaterials, some exposure data for gas-phase reactions are available, but much less information is available regarding liquid-phase reactions. Although the potential for inhaling nanomaterials in a liquid-phase process is less than that for gas-phase, the risks of exposure during wet-chemistry processes are not negligible. In this study, we monitored and analyzed the exposure characteristics of silver nanoparticles during a liquid-phase process in a commercial production facility. Based on the measured exposure data, the source of Ag nanoparticles emitted during the production processes was indentified and a mechanism for the growth of Ag nanoparticle released is proposed. The data reported in this study could be used to establish occupational safety guidelines in the nanotechnology workplace, especially in a liquid-phase production facility.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bahrdt, J.; Frentrup, W.; Gaupp, A.

BESSY plans to build a SASE-FEL facility for the energy range from 20 eV to 1000 eV. The energy range will be covered by three APPLE II type undulators with a magnetic length of about 60 m each. This paper summarizes the basic parameters of the FEL-undulators. The magnetic design will be presented. A modified APPLE II design will be discussed which provides higher fields at the expense of reduced horizontal access. GENESIS simulations give an estimate on the tolerances for the beam wander and for gap errors.

Low Gravity Freefall Facilities

NASA Technical Reports Server (NTRS)

1981-01-01

Composite of Marshall Space Flight Center's Low-Gravity Free Fall Facilities.These facilities include a 100-meter drop tower and a 100-meter drop tube. The drop tower simulates in-flight microgravity conditions for up to 4.2 seconds for containerless processing experiments, immiscible fluids and materials research, pre-flight hardware design test and flight experiment simulation. The drop tube simulates in-flight microgravity conditions for up to 4.6 seconds and is used extensively for ground-based microgravity convection research in which extremely small samples are studied. The facility can provide deep undercooling for containerless processing experiments that require materials to remain in a liquid phase when cooled below the normal solidification temperature.

RF photo-injector beam energy distribution studies by slicing technique

NASA Astrophysics Data System (ADS)

Filippetto, D.; Bellaveglia, M.; Musumeci, P.; Ronsivalle, C.

2009-07-01

The SPARC photo-injector is an R&D facility dedicated to the production of high brightness electron beams for radiation generation via FEL or Thomson scattering processes. It is the prototype injector for the recently approved SPARX project, aiming at the construction in the Frascati/University of Rome Tor Vergata area of a new high brightness electron linac for the generation of SASE-FEL radiation in the 1-10 nm wavelength range. The first phase of the SPARC project has been dedicated to the e-beam source characterization; the beam transverse and longitudinal parameters at the exit of the gun have been measured, and the photo-injector settings optimized to achieve best performance. Several beam dynamics topics have been experimentally studied in this first phase of operation, as, for example, the effect of photocathode driver laser beam shaping and the evolution of the beam transverse emittance. These studies have been made possible by the use of a novel diagnostic tool, the " emittance-meter" which enables the measurement of the transverse beam parameters at different positions along the propagation axis in the very interesting region at the exit of the RF gun. The new idea of extending the e-meter capabilities came out more recently. Information on the beam longitudinal phase space and correlations with the transverse planes can be retrieved by the slicing technique. In this paper, we illustrate the basic concept of the measurement together with simulations that theoretically validate the methodology. Some preliminary results are discussed and explained with the aid of code simulations.

Common Utilities in the Energy Systems Integration Facility | Energy

Science.gov Websites

Systems Integration Facility. Common utilities include: Power: Three-phase 480/277 VAC, 208/120 VAC, 240 split-phase VAC, and 120 single-phase VAC Water: Process heating and cooling and research cooling

Energy Efficient Florida Educational Facilities: Phase VI. Progress Report: Phase I and II.

ERIC Educational Resources Information Center

Callahan, Michael P.; Parker, Danny S.

A Florida study examined differences in energy uses in two adjacent portable classrooms to determine if these types of facilities can be made more energy efficient through retrofitting. Retrofitting included an efficient lighting system, new air conditioners, and reflective white metal roofs. Data show the white metal roofing reduced roof,…

Component Test Facility (Comtest) Phase 1 Engineering For 760°C (1400°F) Advanced Ultrasupercritical (A-USC) Steam Generator Development

DOE Office of Scientific and Technical Information (OSTI.GOV)

Weitzel, Paul

2016-05-13

The Babcock & Wilcox Company (B&W) performed a Pre-Front End Engineering Design (Pre-FEED) of an A-USC steam superheater for a proposed component test program achieving 760°C (1400°F) steam temperature. This would lead to follow-on work in a Phase 2 and Phase 3 that would involve detail design, manufacturing, construction and operation of the ComTest. Phase 1 results have provided the engineering data necessary for proceeding to the next phase of ComTest. The steam generator superheater would subsequently supply the steam to an A-USC prototype intermediate pressure steam turbine. The ComTest program is important in that it will place functioning A-USCmore » components in operation and in coordinated boiler and turbine service. It is also important to introduce the power plant operation and maintenance personnel to the level of skills required and provide the first background experience with hands-on training. The project will provide a means to exercise the complete supply chain events required in order to practice and perfect the process for A-USC power plant design, supply, manufacture, construction, commissioning, operation and maintenance. Representative participants will then be able to transfer knowledge and recommendations to the industry. ComTest is conceived in the manner of using a separate standalone plant facility that will not jeopardize the host facility or suffer from conflicting requirements in the host plant’s mission that could sacrifice the nickel alloy components and not achieve the testing goals. ComTest will utilize smaller quantities of the expensive materials and reduce the risk in the first operational practice for A-USC technology in the United States. Components at suitable scale in ComTest provide more assurance before putting them into practice in the full size A-USC demonstration plant.« less

Time-dependent multi-dimensional simulation studies of the electron output scheme for high power FELs

NASA Astrophysics Data System (ADS)

Hahn, S. J.; Fawley, W. M.; Kim, K. J.; Edighoffer, J. A.

1994-12-01

The authors examine the performance of the so-called electron output scheme recently proposed by the Novosibirsk group. In this scheme, the key role of the FEL oscillator is to induce bunching, while an external undulator, called the radiator, then outcouples the bunched electron beam to optical energy via coherent emission. The level of the intracavity power in the oscillator is kept low by employing a transverse optical klystron (TOK) configuration, thus avoiding excessive thermal loading on the cavity mirrors. Time-dependent effects are important in the operation of the electron output scheme because high gain in the TOK oscillator leads to sideband instabilities and chaotic behavior. The authors have carried out an extensive simulation study by using 1D and 2D time-dependent codes and find that proper control of the oscillator cavity detuning and cavity loss results in high output bunching with a narrow spectral bandwidth. Large cavity detuning in the oscillator and tapering of the radiator undulator is necessary for the optimum output power.

First results from the commissioning of the FERMI@Elettra free electron laser by means of the Photon Analysis Delivery and Reduction System (PADReS)

NASA Astrophysics Data System (ADS)

Zangrando, M.; Cudin, I.; Fava, C.; Gerusina, S.; Gobessi, R.; Godnig, R.; Rumiz, L.; Svetina, C.; Parmigiani, F.; Cocco, D.

2011-06-01

The Italian Free Electron Laser (FEL) facility FERMI@Elettra has started to produce photon radiation at the end of 2010. The photon beam is presently delivered by the first undulator chain (FEL1) that is supposed to produce photons in the 100-20 nm wavelength range. A second undulator chain (FEL2) will be commissioned at the end of 2011, and it will produce radiation in the 20-4nm range. The Photon Analysis Delivery and Reduction System (PADReS) was designed to collect the radiation coming from both the undulator chains (FEL1 and FEL2), to characterize and control it, and to redirect it towards the following beamlines. The first parameters that are checked are the pulse-resolved intensity and beam position. For each of these parameters two dedicated monitors are installed along PADReS on each FEL line. In this way it possible to determine the intensity reduction that is realized by the gas reduction system, which is capable of cutting the intensity by up to four orders of magnitude. The energy distribution of each single pulse is characterized by an online spectrometer installed in the experimental hall. Taking advantage of a variable line-spacing grating it can direct the almost-full beam to the beamlines, while it uses a small fraction of the beam itself to determine the spectral distribution of each pulse delivered by the FEL. The first light of FERMI@Elettra, delivered to the PADReS section in late 2010, is used for the first commissioning runs and some preliminary experiments whose results are reported and discussed in detail.

Free-electron laser emission architecture impact on extreme ultraviolet lithography

NASA Astrophysics Data System (ADS)

Hosler, Erik R.; Wood, Obert R.; Barletta, William A.

2017-10-01

Laser-produced plasma (LPP) EUV sources have demonstrated ˜125 W at customer sites, establishing confidence in EUV lithography (EUVL) as a viable manufacturing technology. However, for extension to the 3-nm technology node and beyond, existing scanner/source technology must enable higher-NA imaging systems (requiring increased resist dose and providing half-field exposures) and/or EUV multipatterning (requiring increased wafer throughput proportional to the number of exposure passes). Both development paths will require a substantial increase in EUV source power to maintain the economic viability of the technology, creating an opportunity for free-electron laser (FEL) EUV sources. FEL-based EUV sources offer an economic, high-power/single-source alternative to LPP EUV sources. Should FELs become the preferred next-generation EUV source, the choice of FEL emission architecture will greatly affect its operational stability and overall capability. A near-term industrialized FEL is expected to utilize one of the following three existing emission architectures: (1) self-amplified spontaneous emission, (2) regenerative amplifier, or (3) self-seeding. Model accelerator parameters are put forward to evaluate the impact of emission architecture on FEL output. Then, variations in the parameter space are applied to assess the potential impact to lithography operations, thereby establishing component sensitivity. The operating range of various accelerator components is discussed based on current accelerator performance demonstrated at various scientific user facilities. Finally, comparison of the performance between the model accelerator parameters and the variation in parameter space provides a means to evaluate the potential emission architectures. A scorecard is presented to facilitate this evaluation and provides a framework for future FEL design and enablement for EUVL applications.

Establishment of a National Accelerator Facility: Design and construction phase

NASA Astrophysics Data System (ADS)

1981-06-01

The main components of an accelerator facility for nuclear physics, isotope production, and radiotherapy in South Africa are in 8-MeV solid pole injector cyclotron and a separated sector cyclotron with a k-value of 200 MeV. Progress made in the development of the light ion injector and in the design of the control and beam transport systems is described. Mechanical and engineering tasks associated with component manufacture are discussed as well as the construction of the building to house the facility and the installation of necessary services.

Wakefield computations for a corrugated pipe as a beam dechirper for FEL applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ng, C. K.; Bane, K. L.F.

A beam “dechirper” based on a corrugated, metallic vacuum chamber has been proposed recently to cancel residual energy chirp in a beam before it enters the undulator in a linac-based X-ray FEL. Rather than the round geometry that was originally proposed, we consider a pipe composed of two parallel plates with corrugations. The advantage is that the strength of the wake effect can be tuned by adjusting the separation of the plates. The separation of the plates is on the order of millimeters, and the corrugations are fractions of a millimeter in size. The dechirper needs to be meters longmore » in order to provide sufficient longitudinal wakefield to cancel the beam chirp. Considerable computation resources are required to determine accurately the wakefield for such a long structure with small corrugation gaps. Combining the moving window technique and parallel computing using multiple processors, the time domain module in the parallel finite-element electromagnetic suite ACE3P allows efficient determination of the wakefield through convergence studies. In this paper, we will calculate the longitudinal, dipole and quadrupole wakefields for the dechirper and compare the results with those of analytical and field matching approaches.« less

Lewis Research Center space station electric power system test facilities

NASA Technical Reports Server (NTRS)

Birchenough, Arthur G.; Martin, Donald F.

1988-01-01

NASA Lewis Research Center facilities were developed to support testing of the Space Station Electric Power System. The capabilities and plans for these facilities are described. The three facilities which are required in the Phase C/D testing, the Power Systems Facility, the Space Power Facility, and the EPS Simulation Lab, are described in detail. The responsibilities of NASA Lewis and outside groups in conducting tests are also discussed.

Emerging opportunities in structural biology with X-ray free-electron lasers

PubMed Central

Schlichting, Ilme; Miao, Jianwei

2012-01-01

X-ray free-electron lasers (X-FELs) produce X-ray pulses with extremely brilliant peak intensity and ultrashort pulse duration. It has been proposed that radiation damage can be “outrun” by using an ultra intense and short X-FEL pulse that passes a biological sample before the onset of significant radiation damage. The concept of “diffraction-before-destruction” has been demonstrated recently at the Linac Coherent Light Source, the first operational hard X-ray FEL, for protein nanocrystals and giant virus particles. The continuous diffraction patterns from single particles allow solving the classical “phase problem” by the oversampling method with iterative algorithms. If enough data are collected from many identical copies of a (biological) particle, its three-dimensional structure can be reconstructed. We review the current status and future prospects of serial femtosecond crystallography (SFX) and single-particle coherent diffraction imaging (CDI) with X-FELs. PMID:22922042

Facile purification and click labeling with 2-[ 18F]fluoroethyl azide using solid phase extraction cartridges

DOE PAGES

Zhou, Dong; Chu, Wenhua; Peng, Xin; ...

2014-11-04

In this paper, a facile method was developed to purify 2-[ 18F]fluoroethyl azide ([ 18F]FEA) using a C18 cartridge and an Oasis® HLB cartridge in series, in which [18F]FEA was exclusively trapped on the HLB cartridge. [ 18F]FEA can be eluted for reactions in solution; alternatively click labeling can be carried out on the HLB cartridge itself by loading an alkyne substrate and copper (I) catalyst dissolved in DMF onto the cartridge. Finally, this solid phase extraction methodology for purification and click labeling with [ 18F]FEA, either in solution or on the cartridge, is safe, simple, reproducible in high yield,more » and compatible with automated synthesis of 18F-labeled PET tracers.« less

Facilities Audit Workbook: A Self-Evaluation for Higher Education.

ERIC Educational Resources Information Center

Kaiser, Harvey H.

The purpose and scope of a facilities audit and steps in conducting an audit are outlined, and facility ratings forms that can be used in the process are included. The audit is presented as a part of the comprehensive facilities management approach, and the users and different audit uses are also addressed. The audit design phase includes deciding…

VOCATIONAL-TECHNICAL FACILITIES PROJECT. PROGRESS REPORT.

ERIC Educational Resources Information Center

CONRAD, M.J.; VALENTINE, I.E.

IN THE FIRST PHASE OF A PROJECT FOR DEVELOPING PLANNING GUIDES FOR VOCATIONAL FACILITIES, THE OVERALL DIRECTION OF A SERIES OF PLANNING GUIDES IS BEING DETERMINED. IN THE SECOND PHASE AT LEAST ONE PLANNING MANUAL WILL BE DEVELOPED TO SERVE AS A MODEL FOR THE FULL SERIES. A LOCAL WORKING GROUP COMPOSED OF THREE SPECIALISTS FROM THE CENTER FOR…

Spent nuclear fuel project cold vacuum drying facility operations manual

DOE Office of Scientific and Technical Information (OSTI.GOV)

IRWIN, J.J.

This document provides the Operations Manual for the Cold Vacuum Drying Facility (CVDF). The Manual was developed in conjunction with HNF-SD-SNF-SAR-002, Safety Analysis Report for the Cold Vacuum Drying Facility, Phase 2, Supporting Installation of Processing Systems (Garvin 1998) and, the HNF-SD-SNF-DRD-002, 1997, Cold Vacuum Drying Facility Design Requirements, Rev. 3a. The Operations Manual contains general descriptions of all the process, safety and facility systems in the CVDF, a general CVD operations sequence, and has been developed for the SNFP Operations Organization and shall be updated, expanded, and revised in accordance with future design, construction and startup phases of themore » CVDF until the CVDF final ORR is approved.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Carr, Roger

The VISA (Visible to Infrared SASE Amplifier) FEL is designed to obtain high gain at a radiation wavelength of 800nm. The FEL uses the high brightness electron beam of the Accelerator Test Facility (ATF), with energy of 72MeV. VISA uses a novel, 4 m long, strong focusing undulator with a gap of 6mm and a period of 1.8cm. To obtain large gain the beam and undulator axis have to be aligned to better than 50{micro}m. Results from initial measurements on the alignment, gain, and spectrum will be presented and compared to theoretical calculations and simulations.

Possibilities for serial femtosecond crystallography sample delivery at future light sourcesa)

PubMed Central

Chavas, L. M. G.; Gumprecht, L.; Chapman, H. N.

2015-01-01

Serial femtosecond crystallography (SFX) uses X-ray pulses from free-electron laser (FEL) sources that can outrun radiation damage and thereby overcome long-standing limits in the structure determination of macromolecular crystals. Intense X-ray FEL pulses of sufficiently short duration allow the collection of damage-free data at room temperature and give the opportunity to study irreversible time-resolved events. SFX may open the way to determine the structure of biological molecules that fail to crystallize readily into large well-diffracting crystals. Taking advantage of FELs with high pulse repetition rates could lead to short measurement times of just minutes. Automated delivery of sample suspensions for SFX experiments could potentially give rise to a much higher rate of obtaining complete measurements than at today's third generation synchrotron radiation facilities, as no crystal alignment or complex robotic motions are required. This capability will also open up extensive time-resolved structural studies. New challenges arise from the resulting high rate of data collection, and in providing reliable sample delivery. Various developments for fully automated high-throughput SFX experiments are being considered for evaluation, including new implementations for a reliable yet flexible sample environment setup. Here, we review the different methods developed so far that best achieve sample delivery for X-ray FEL experiments and present some considerations towards the goal of high-throughput structure determination with X-ray FELs. PMID:26798808

A health maintenance facility for space station freedom

NASA Technical Reports Server (NTRS)

Billica, R. D.; Doarn, C. R.

1991-01-01

We describe a health care facility to be built and used on an orbiting space station in low Earth orbit. This facility, called the health maintenance facility, is based on and modeled after isolated terrestrial medical facilities. It will provide a phased approach to health care for the crews of Space Station Freedom. This paper presents the capabilities of the health maintenance facility. As Freedom is constructed over the next decade there will be an increase in activities, both construction and scientific. The health maintenance facility will evolve with this process until it is a mature, complete, stand-alone health care facility that establishes a foundation to support interplanetary travel. As our experience in space continues to grow so will the commitment to providing health care.

An imaging dataset of cervical cells using scanning near-field optical microscopy coupled to an infrared free electron laser.

PubMed

Halliwell, Diane E; Morais, Camilo L M; Lima, Kássio M G; Trevisan, Júlio; Siggel-King, Michele R F; Craig, Tim; Ingham, James; Martin, David S; Heys, Kelly; Kyrgiou, Maria; Mitra, Anita; Paraskevaidis, Evangelos; Theophilou, Georgios; Martin-Hirsch, Pierre L; Cricenti, Antonio; Luce, Marco; Weightman, Peter; Martin, Francis L

2017-07-11

Using a scanning near-field optical microscope coupled to an infrared free electron laser (SNOM-IR-FEL) in low-resolution transmission mode, we collected chemical data from whole cervical cells obtained from 5 pre-menopausal, non-pregnant women of reproductive age, and cytologically classified as normal or with different grades of cervical cell dyskaryosis. Imaging data are complemented by demography. All samples were collected before any treatment. Spectra were also collected using attenuated total reflection, Fourier-transform (ATR-FTIR) spectroscopy, to investigate the differences between the two techniques. Results of this pilot study suggests SNOM-IR-FEL may be able to distinguish cervical abnormalities based upon changes in the chemical profiles for each grade of dyskaryosis at designated wavelengths associated with DNA, Amide I/II, and lipids. The novel data sets are the first collected using SNOM-IR-FEL in transmission mode at the ALICE facility (UK), and obtained using whole cells as opposed to tissue sections, thus providing an 'intact' chemical profile. These data sets are suited to complementing future work on image analysis, and/or applying the newly developed algorithm to other datasets collected using the SNOM-IR-FEL approach.

An imaging dataset of cervical cells using scanning near-field optical microscopy coupled to an infrared free electron laser

NASA Astrophysics Data System (ADS)

Halliwell, Diane E.; Morais, Camilo L. M.; Lima, Kássio M. G.; Trevisan, Júlio; Siggel-King, Michele R. F.; Craig, Tim; Ingham, James; Martin, David S.; Heys, Kelly; Kyrgiou, Maria; Mitra, Anita; Paraskevaidis, Evangelos; Theophilou, Georgios; Martin-Hirsch, Pierre L.; Cricenti, Antonio; Luce, Marco; Weightman, Peter; Martin, Francis L.

2017-07-01

Using a scanning near-field optical microscope coupled to an infrared free electron laser (SNOM-IR-FEL) in low-resolution transmission mode, we collected chemical data from whole cervical cells obtained from 5 pre-menopausal, non-pregnant women of reproductive age, and cytologically classified as normal or with different grades of cervical cell dyskaryosis. Imaging data are complemented by demography. All samples were collected before any treatment. Spectra were also collected using attenuated total reflection, Fourier-transform (ATR-FTIR) spectroscopy, to investigate the differences between the two techniques. Results of this pilot study suggests SNOM-IR-FEL may be able to distinguish cervical abnormalities based upon changes in the chemical profiles for each grade of dyskaryosis at designated wavelengths associated with DNA, Amide I/II, and lipids. The novel data sets are the first collected using SNOM-IR-FEL in transmission mode at the ALICE facility (UK), and obtained using whole cells as opposed to tissue sections, thus providing an 'intact' chemical profile. These data sets are suited to complementing future work on image analysis, and/or applying the newly developed algorithm to other datasets collected using the SNOM-IR-FEL approach.

An imaging dataset of cervical cells using scanning near-field optical microscopy coupled to an infrared free electron laser

PubMed Central

Halliwell, Diane E.; Morais, Camilo L.M.; Lima, Kássio M.G.; Trevisan, Júlio; Siggel-King, Michele R.F.; Craig, Tim; Ingham, James; Martin, David S.; Heys, Kelly; Kyrgiou, Maria; Mitra, Anita; Paraskevaidis, Evangelos; Theophilou, Georgios; Martin-Hirsch, Pierre L.; Cricenti, Antonio; Luce, Marco; Weightman, Peter; Martin, Francis L.

2017-01-01

Using a scanning near-field optical microscope coupled to an infrared free electron laser (SNOM-IR-FEL) in low-resolution transmission mode, we collected chemical data from whole cervical cells obtained from 5 pre-menopausal, non-pregnant women of reproductive age, and cytologically classified as normal or with different grades of cervical cell dyskaryosis. Imaging data are complemented by demography. All samples were collected before any treatment. Spectra were also collected using attenuated total reflection, Fourier-transform (ATR-FTIR) spectroscopy, to investigate the differences between the two techniques. Results of this pilot study suggests SNOM-IR-FEL may be able to distinguish cervical abnormalities based upon changes in the chemical profiles for each grade of dyskaryosis at designated wavelengths associated with DNA, Amide I/II, and lipids. The novel data sets are the first collected using SNOM-IR-FEL in transmission mode at the ALICE facility (UK), and obtained using whole cells as opposed to tissue sections, thus providing an ‘intact’ chemical profile. These data sets are suited to complementing future work on image analysis, and/or applying the newly developed algorithm to other datasets collected using the SNOM-IR-FEL approach. PMID:28696426

A Smoluchowski model of crystallization dynamics of small colloidal clusters

NASA Astrophysics Data System (ADS)

Beltran-Villegas, Daniel J.; Sehgal, Ray M.; Maroudas, Dimitrios; Ford, David M.; Bevan, Michael A.

2011-10-01

We investigate the dynamics of colloidal crystallization in a 32-particle system at a fixed value of interparticle depletion attraction that produces coexisting fluid and solid phases. Free energy landscapes (FELs) and diffusivity landscapes (DLs) are obtained as coefficients of 1D Smoluchowski equations using as order parameters either the radius of gyration or the average crystallinity. FELs and DLs are estimated by fitting the Smoluchowski equations to Brownian dynamics (BD) simulations using either linear fits to locally initiated trajectories or global fits to unbiased trajectories using Bayesian inference. The resulting FELs are compared to Monte Carlo Umbrella Sampling results. The accuracy of the FELs and DLs for modeling colloidal crystallization dynamics is evaluated by comparing mean first-passage times from BD simulations with analytical predictions using the FEL and DL models. While the 1D models accurately capture dynamics near the free energy minimum fluid and crystal configurations, predictions near the transition region are not quantitatively accurate. A preliminary investigation of ensemble averaged 2D order parameter trajectories suggests that 2D models are required to capture crystallization dynamics in the transition region.

Lunar base launch and landing facilities conceptual design

NASA Technical Reports Server (NTRS)

Phillips, Paul G.; Simonds, Charles H.; Stump, William R.

1992-01-01

The purpose of this study was to perform a first look at the requirements for launch and landing facilities for early lunar bases and to prepared conceptual designs for some of these facilities. The emphasis of the study is on the facilities needed from the first manned landing until permanent occupancy, the Phase 2 lunar base. Factors including surface characteristics, navigation system, engine blast effects, and expected surface operations are used to develop landing pad designs, and definitions fo various other elements of the launch and landing facilities. Finally, the dependence of the use of these elements and the evolution of the facilities are established.

Time-dependent multi-dimensional simulation studies of the electron output scheme for high power FELs

NASA Astrophysics Data System (ADS)

Hahn, S. J.; Fawley, W. M.; Kim, K.-J.; Edighoffer, J. A.

1995-04-01

We examine the performance of the so-called electron output scheme recently proposed by the Novosibirsk group [G.I. Erg et al., 15th Int. Free Electron Laser Conf., The Hague, The Netherlands, 1993, Book of Abstracts p. 50; Preprint Budker INP 93-75]. In this scheme, the key role of the FEL oscillator is to induce bunching, while an external undulator, called the radiator, then outcouples the bunched electron beam to optical energy via coherent emission. The level of the intracavity power in the oscillator is kept low by employing a transverse optical klystron (TOK) configuration, thus avoiding excessive thermal loading on the cavity mirrors. Time-dependent effects are important in the operation of the electron output scheme because high gain in the TOK oscillator leads to sideband instabilities and chaotic behavior. We have carried out an extensive simulation study by using 1D and 2D time-dependent codes and find that proper control of the oscillator cavity detuning and cavity loss results in high output bunching with a narrow spectral bandwidth. Large cavity detuning in the oscillator and tapering of the radiator undulator is necessary for the optimum output power.

Studies Of Coherent Synchrotron Radiation And Longitudinal Space Charge In The Jefferson Lab FEL Driver

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tennant, Christopher D.; Douglas, David R.; Li, Rui

2014-12-01

The Jefferson Laboratory IR FEL Driver provides an ideal test bed for studying a variety of beam dynamical effects. Recent studies focused on characterizing the impact of coherent synchrotron radiation (CSR) with the goal of benchmarking measurements with simulation. Following measurements to characterize the beam, we quantitatively characterized energy extraction via CSR by measuring beam position at a dispersed location as a function of bunch compression. In addition to operating with the beam on the rising part of the linac RF waveform, measurements were also made while accelerating on the falling part. For each, the full compression point was movedmore » along the backleg of the machine and the response of the beam (distribution, extracted energy) measured. Initial results of start-to-end simulations using a 1D CSR algorithm show remarkably good agreement with measurements. A subsequent experiment established lasing with the beam accelerated on the falling side of the RF waveform in conjunction with positive momentum compaction (R56) to compress the bunch. The success of this experiment motivated the design of a modified CEBAF-style arc with control of CSR and microbunching effects.« less

UTEX: integrated ultraviolet and x-ray astronomy facility on spacelab, phase a study. Volume 2: facility definition. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1976-07-01

The definition and feasibility study of an integrated ultraviolet and astronomy facility onboard Spacelab are presented. This is based on the scientific aims of different European countries. The accommodation of such a facility in the first and second Spacelab flights was also studied, taking into account external constraints of both flights and the possibility of future missions. Well identified possible work packages are outlined in view of future international cooperation.

Experimental geometry for simultaneous beam characterization and sample imaging allowing for pink beam Fourier transform holography or coherent diffractive imaging

DOE Office of Scientific and Technical Information (OSTI.GOV)

Flewett, Samuel; Eisebitt, Stefan

2011-02-20

One consequence of the self-amplified stimulated emission process used to generate x rays in free electron lasers (FELs) is the intrinsic shot-to-shot variance in the wavelength and temporal coherence. In order to optimize the results from diffractive imaging experiments at FEL sources, it will be advantageous to acquire a means of collecting coherence and spectral information simultaneously with the diffraction pattern from the sample we wish to study. We present a holographic mask geometry, including a grating structure, which can be used to extract both temporal and spatial coherence information alongside the sample scatter from each individual FEL shot andmore » also allows for the real space reconstruction of the sample using either Fourier transform holography or iterative phase retrieval.« less

Simulation Facilities and Test Beds for Galileo

NASA Astrophysics Data System (ADS)

Schlarmann, Bernhard Kl.; Leonard, Arian

2002-01-01

Galileo is the European satellite navigation system, financed by the European Space Agency (ESA) and the European Commission (EC). The Galileo System, currently under definition phase, will offer seamless global coverage, providing state-of-the-art positioning and timing services. Galileo services will include a standard service targeted at mass market users, an augmented integrity service, providing integrity warnings when fault occur and Public Regulated Services (ensuring a continuity of service for the public users). Other services are under consideration (SAR and integrated communications). Galileo will be interoperable with GPS, and will be complemented by local elements that will enhance the services for specific local users. In the frame of the Galileo definition phase, several system design and simulation facilities and test beds have been defined and developed for the coming phases of the project, respectively they are currently under development. These are mainly the following tools: Galileo Mission Analysis Simulator to design the Space Segment, especially to support constellation design, deployment and replacement. Galileo Service Volume Simulator to analyse the global performance requirements based on a coverage analysis for different service levels and degrades modes. Galileo System Simulation Facility is a sophisticated end-to-end simulation tool to assess the navigation performances for a complete variety of users under different operating conditions and different modes. Galileo Signal Validation Facility to evaluate signal and message structures for Galileo. Galileo System Test Bed (Version 1) to assess and refine the Orbit Determination &Time Synchronisation and Integrity algorithms, through experiments relying on GPS space infrastructure. This paper presents an overview on the so called "G-Facilities" and describes the use of the different system design tools during the project life cycle in order to design the system with respect to

Coupled Facility/Payload Vibration Modeling Improvements

NASA Technical Reports Server (NTRS)

Carnahan, Timothy M.; Kaiser, Michael

2015-01-01

A major phase of aerospace hardware verification is vibration testing. The standard approach for such testing is to use a shaker to induce loads into the payload. In preparation for vibration testing at NASA/GSFC there is an analysis to assess the responses of the payload. A new method of modeling the test is presented that takes into account dynamic interactions between the facility and the payload. This dynamic interaction has affected testing in the past, but been ignored or adjusted for during testing. By modeling the combination of the facility and test article (payload) it is possible to improve the prediction of hardware responses. Many aerospace test facilities work in similar way to those at NASA Goddard Space Flight Center. Lessons learned here should be applicable to other test facilities with similar setups.

From Macromolecular to Small-Molecular Triggers: Facile Method toward Photoinduced LCST Phase Behavior of Thermoresponsive Polymers in Mixed Ionic Liquids Containing an Azobenzene Moiety.

PubMed

Wang, Caihong; Ma, Xiaofeng; Kitazawa, Yuzo; Kobayashi, Yumi; Zhang, Shiguo; Kokubo, Hisashi; Watanabe, Masayoshi

2016-12-01

Instead of the reported photoinduced lower critical solution temperature (LCST) phase transition behavior in ionic liquids (ILs) achieved by photofunctional polymers, this study reports the facile photoinduced LCST phase behavior of nonfunctionalized polymers (poly(benzyl methacrylate) (PBnMA) and poly(2-phenylethyl methacrylate) (PPhEtMA)) in mixed ILs (1,3-dimethylimidazolium bis(trifluoromethanesulfonyl)amide; [C 1 mim][NTf 2 ] and a newly designed functionalized IL containing an azobenzene moiety (1-butyl-3-(4-phenylazobenzyl)imidazolium bis(trifluoromethanesulfonyl)amide; [Azo][NTf 2 ])) as a small-molecular photo trigger. Interestingly, the length of the alkyl spacer between the ester and aryl groups, which is the only structural difference between the two polymers, leads to two different photoresponsive LCST phase transition behaviors. On the basis of spectroscopic studies, the different phase transition behaviors of PBnMA and PPhEtMA may attribute to the different cooperative interactions between the polymers and [C 1 mim][NTf 2 ]. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Microbunching-instability-induced sidebands in a seeded free-electron laser

DOE PAGES

Zhang, Zhen; Lindberg, Ryan; Fawley, William M.; ...

2016-05-02

Measurements of the multishot-averaged, soft x-ray, self-seeding spectrum at the LCLS free-electron laser often have a pedestal-like distribution around the seeded wavelength, which limits the spectral purity and can negatively affect some user applications not employing a post-undulator monochromator. In this paper, we study the origins of such pedestals, focusing on longitudinal phase space modulations produced by the microbunching instability upstream of the free-electron laser (FEL) undulator. Furthermore, we show from theory and numerical simulation that both energy and density modulations can induce sidebands in a high-gain, seeded FEL whose fractional strength typically grows as the square of the undulatormore » length. The results place a tight constraint on the longitudinal phase space uniformity of the electron beam for a seeded FEL, possibly requiring the amplitude of long-wavelength modulations to be much smaller than the typical incoherent energy spread if the output sideband power is to remain only a couple percent or less of the amplified seed power.« less

Compact beam transport system for free-electron lasers driven by a laser plasma accelerator

DOE PAGES

Liu, Tao; Zhang, Tong; Wang, Dong; ...

2017-02-01

Utilizing laser-driven plasma accelerators (LPAs) as a high-quality electron beam source is a promising approach to significantly downsize the x-ray free-electron laser (XFEL) facility. A multi-GeV LPA beam can be generated in several-centimeter acceleration distance, with a high peak current and a low transverse emittance, which will considerably benefit a compact FEL design. However, the large initial angular divergence and energy spread make it challenging to transport the beam and realize FEL radiation. In this paper, a novel design of beam transport system is proposed to maintain the superior features of the LPA beam and a transverse gradient undulator (TGU)more » is also adopted as an effective energy spread compensator to generate high-brilliance FEL radiation. As a result, theoretical analysis and numerical simulations are presented based on a demonstration experiment with an electron energy of 380 MeV and a radiation wavelength of 30 nm.« less

Photon-in photon-out hard X-ray spectroscopy at the Linac Coherent Light Source

DOE PAGES

Alonso-Mori, Roberto; Sokaras, Dimosthenis; Zhu, Diling; ...

2015-04-15

X-ray free-electron lasers (FELs) have opened unprecedented possibilities to study the structure and dynamics of matter at an atomic level and ultra-fast timescale. Many of the techniques routinely used at storage ring facilities are being adapted for experiments conducted at FELs. In order to take full advantage of these new sources several challenges have to be overcome. They are related to the very different source characteristics and its resulting impact on sample delivery, X-ray optics, X-ray detection and data acquisition. Here it is described how photon-in photon-out hard X-ray spectroscopy techniques can be applied to study the electronic structure andmore » its dynamics of transition metal systems with ultra-bright and ultra-short FEL X-ray pulses. In particular, some of the experimental details that are different compared with synchrotron-based setups are discussed and illustrated by recent measurements performed at the Linac Coherent Light Source.« less

Initial application of a dual-sweep streak camera to the Duke storage ring OK-4 source

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lumpkin, A.H.; Yang, B.X.; Litvinenko, V.

1997-08-01

The visible and UV spontaneous emission radiation (SER) from the Duke OK-4 wiggler has been used with a Hamamatsu C5680 dual-sweep streak camera to characterize the stored electron beams. Particle beam energies of 270 and 500 MeV in the Duke storage ring were used in this initial application with the OK-4 adjusted to generate wavelengths from 500 nm to near 200 nm. The OK-4 magnetic system with its 68 periods provided a much stronger radiation source than a nearby bending magnet source point. Sensitivity to single-bunch, single-turn SER was shown down to 4 {mu}A beam current at {lambda} = 450more » nm. The capability of seeing second passes in the FEL resonator at a wavelength near 200 nm was used to assess the cavity length versus orbit length. These tests (besides supporting preparation for UV-visible SR FEL startups) are also relevant to possible diagnostics techniques for single-pass FEL prototype facilities.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

TREMAINE,A.; MUROKH,A.; WANG,X.J.

The VISA experiment is designed to reach and study saturation in a high gain 800nm SASE FEL at the Brookhaven Accelerator Test Facility (ATF). To do this, the undulator must be aligned at first to within 20 {micro}m with use of a laser interferometric system. Once aligned, any small movements from the aligned position will greatly detriment the SASE FEL performance thus making continuous monitoring of the undulator position necessary. This is quite a complicated task since the 4m undulator is made up of four 1m sections enclosed in a vacuum chamber. We have developed an in situ optical systemmore » to monitor the undulator position with an accuracy better than 10 {micro}m. In addition, we have demonstrated the accuracy of this system by bringing the grossly misaligned VISA undulator ({approximately} 500 {micro}m in some locations) into alignment and attaining very high gain of the SASE FEL.« less

ER@CEBAF: A test of 5-pass energy recovery at CEBAF

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bogacz, S. A.; Douglas, D.; Dubbe, C.

2016-06-06

Jefferson Lab personnel have broad expertise in the design, commissioning, and operation of multiple energy recovery linacs (ERLs): the CEBAF Front-End Test (early 1990s), CEBAF-ER (2003), the IR Free Electron Laser (FEL) Demo, the IR FEL Upgrade, and the UV FEL Driver (1997-2014). Continued development of this core competency has led to this collaborative proposal to explore the forefronts of ERL technology at high energy in a unique expansion of CEBAF capability to a 5-pass ERL with negligible switchover time and programmatic impact to the CEBAF physics program. Such a capability would enable world-class studies of open issues in high-energymore » ERL beam dynamics that are relevant to future facilities such as electron-ion colliders (EICs). This proposal requests support from the CEBAF Program Advisory Committee to seek funding for hardware installation, and a prospective 12 days of beam time circa Fall 2018 for commissioning this high-energy multi-pass ERL experiment in CEBAF.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sehgal, Ray M.; Maroudas, Dimitrios, E-mail: maroudas@ecs.umass.edu, E-mail: ford@ecs.umass.edu; Ford, David M., E-mail: maroudas@ecs.umass.edu, E-mail: ford@ecs.umass.edu

We have developed a coarse-grained description of the phase behavior of the isolated 38-atom Lennard-Jones cluster (LJ{sub 38}). The model captures both the solid-solid polymorphic transitions at low temperatures and the complex cluster breakup and melting transitions at higher temperatures. For this coarse model development, we employ the manifold learning technique of diffusion mapping. The outcome of the diffusion mapping analysis over a broad temperature range indicates that two order parameters are sufficient to describe the cluster's phase behavior; we have chosen two such appropriate order parameters that are metrics of condensation and overall crystallinity. In this well-justified coarse-variable space,more » we calculate the cluster's free energy landscape (FEL) as a function of temperature, employing Monte Carlo umbrella sampling. These FELs are used to quantify the phase behavior and onsets of phase transitions of the LJ{sub 38} cluster.« less

Self-Generated Magnetic Fields in the Stagnation Phase of Indirect-Drive Implosions on the National Ignition Facility

NASA Astrophysics Data System (ADS)

Walsh, C. A.; Chittenden, J. P.; McGlinchey, K.; Niasse, N. P. L.; Appelbe, B. D.

2017-04-01

Three-dimensional extended-magnetohydrodynamic simulations of the stagnation phase of inertial confinement fusion implosion experiments at the National Ignition Facility are presented, showing self-generated magnetic fields over 104 T . Angular high mode-number perturbations develop large magnetic fields, but are localized to the cold, dense hot-spot surface, which is hard to magnetize. When low-mode perturbations are also present, the magnetic fields are injected into the hot core, reaching significant magnetizations, with peak local thermal conductivity reductions greater than 90%. However, Righi-Leduc heat transport effectively cools the hot spot and lowers the neutron spectra-inferred ion temperatures compared to the unmagnetized case. The Nernst effect qualitatively changes the results by demagnetizing the hot-spot core, while increasing magnetizations at the edge and near regions of large heat loss.

Self-Generated Magnetic Fields in the Stagnation Phase of Indirect-Drive Implosions on the National Ignition Facility.

PubMed

Walsh, C A; Chittenden, J P; McGlinchey, K; Niasse, N P L; Appelbe, B D

2017-04-14

Three-dimensional extended-magnetohydrodynamic simulations of the stagnation phase of inertial confinement fusion implosion experiments at the National Ignition Facility are presented, showing self-generated magnetic fields over 10^{4}  T. Angular high mode-number perturbations develop large magnetic fields, but are localized to the cold, dense hot-spot surface, which is hard to magnetize. When low-mode perturbations are also present, the magnetic fields are injected into the hot core, reaching significant magnetizations, with peak local thermal conductivity reductions greater than 90%. However, Righi-Leduc heat transport effectively cools the hot spot and lowers the neutron spectra-inferred ion temperatures compared to the unmagnetized case. The Nernst effect qualitatively changes the results by demagnetizing the hot-spot core, while increasing magnetizations at the edge and near regions of large heat loss.

Space exploration initiative candidate nuclear propulsion test facilities

NASA Technical Reports Server (NTRS)

Baldwin, Darrell; Clark, John S.

1993-01-01

One-page descriptions for approximately 200 existing government, university, and industry facilities which may be available in the future to support SEI nuclear propulsion technology development and test program requirements are provided. To facilitate use of the information, the candidate facilities are listed both by location (Index L) and by Facility Type (Index FT). The included one-page descriptions provide a brief narrative description of facility capability, suggest potential uses for each facility, and designate a point of contact for additional information that may be needed in the future. The Nuclear Propulsion Office at NASA Lewis presently plans to maintain, expand, and update this information periodically for use by NASA, DOE, and DOD personnel involved in planning various phases of the SEI Nuclear Propulsion Project.

Coupled Facility-Payload Vibration Modeling Improvements

NASA Technical Reports Server (NTRS)

Carnahan, Timothy M.; Kaiser, Michael A.

2015-01-01

A major phase of aerospace hardware verification is vibration testing. The standard approach for such testing is to use a shaker to induce loads into the payload. In preparation for vibration testing at National Aeronautics and Space Administration/Goddard Space Flight Center an analysis is performed to assess the responses of the payload. A new method of modeling the test is presented that takes into account dynamic interactions between the facility and the payload. This dynamic interaction has affected testing in the past, but been ignored or adjusted for during testing. By modeling the combined dynamics of the facility and test article (payload) it is possible to improve the prediction of hardware responses. Many aerospace test facilities work in similar way to those at NASA/Goddard Space Flight Center. Lessons learned here should be applicable to other test facilities with similar setups.

Single-shot coherent diffraction imaging of microbunched relativistic electron beams for free-electron laser applications.

PubMed

Marinelli, A; Dunning, M; Weathersby, S; Hemsing, E; Xiang, D; Andonian, G; O'Shea, F; Miao, Jianwei; Hast, C; Rosenzweig, J B

2013-03-01

With the advent of coherent x rays provided by the x-ray free-electron laser (FEL), strong interest has been kindled in sophisticated diffraction imaging techniques. In this Letter, we exploit such techniques for the diagnosis of the density distribution of the intense electron beams typically utilized in an x-ray FEL itself. We have implemented this method by analyzing the far-field coherent transition radiation emitted by an inverse-FEL microbunched electron beam. This analysis utilizes an oversampling phase retrieval method on the transition radiation angular spectrum to reconstruct the transverse spatial distribution of the electron beam. This application of diffraction imaging represents a significant advance in electron beam physics, having critical applications to the diagnosis of high-brightness beams, as well as the collective microbunching instabilities afflicting these systems.

Life Sciences Centrifuge Facility review

NASA Technical Reports Server (NTRS)

Young, Laurence R.

1994-01-01

The Centrifuge Facility Project at ARC was reviewed by a code U team to determine appropriateness adequacy for the ISSA. This report represents the findings of one consultant to this team and concentrates on scientific and technical risks. This report supports continuation of the project to the next phase of development.

Cryogenic Fluid Management Facility

NASA Technical Reports Server (NTRS)

Eberhardt, R. N.; Bailey, W. J.

1985-01-01

The Cryogenic Fluid Management Facility is a reusable test bed which is designed to be carried within the Shuttle cargo bay to investigate the systems and technologies associated with the efficient management of cryogens in space. Cryogenic fluid management consists of the systems and technologies for: (1) liquid storage and supply, including capillary acquisition/expulsion systems which provide single-phase liquid to the user system, (2) both passive and active thermal control systems, and (3) fluid transfer/resupply systems, including transfer lines and receiver tanks. The facility contains a storage and supply tank, a transfer line and a receiver tank, configured to provide low-g verification of fluid and thermal models of cryogenic storage and transfer processes. The facility will provide design data and criteria for future subcritical cryogenic storage and transfer system applications, such as Space Station life support, attitude control, power and fuel depot supply, resupply tankers, external tank (ET) propellant scavenging, and ground-based and space-based orbit transfer vehicles (OTV).

Comparative study of nonideal beam effects in high gain harmonic generation and self-seeded free electron lasers

NASA Astrophysics Data System (ADS)

Marinelli, Agostino; Pellegrini, Claudio; Giannessi, Luca; Reiche, Sven

2010-07-01

In this paper we investigate and compare the properties of two narrow-bandwidth free-electron laser (FEL) schemes, one using self-seeding and the other high gain harmonic generation (HGHG). The two systems have been thoroughly studied analytically and numerically in the past. The aim of this work is to compare their performances when the FEL is driven by an electron beam with nonideal properties, thus including effects such as shot-to-shot energy fluctuations and nonlinear energy chirp. In both cases nonlinearities produce a bandwidth larger than the Fourier transform limited value. However, our analysis indicates that, for approximately the same output power levels, the self-seeding scheme is less affected than the HGHG scheme by quadratic energy chirps in the electron beam longitudinal phase space. This is confirmed by a specific numerical example corresponding to SPARX parameters where the electron beam was optimized to minimize the FEL gain length. The work has been carried out with the aid of the time dependent FEL codes GENESIS 1.3 (3D) and PERSEO (1D).

Environmental Survey preliminary report, Pantex Facility, Amarillo, Texas

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

This report presents the preliminary findings from the first phase of the Environmental Survey of the United States Department of Energy (DOE) Pantex Facility, conducted November 3 through 14, 1986.The Survey is being conducted by an interdisciplinary team of environmental specialist, led and managed by the Office of Environment, Safety and Health's Office of Environmental Audit. Individual team components are outside experts being supplied by a private contractor. The objective of the Survey is to identify environmental problems and areas of environmental risk associated with the Pantex Facility. The Survey covers all environmental media and all areas of environmental regulation.more » It is being performed in accordance with the DOE Environmental Survey Manual. The on-site phase of the Survey involves the review of existing site environmental data, observations of the operations carried on at the Pantex Facility, and interviews with site personnel. The Survey team developed a Sampling and Analysis Plan to assist in further assessing certain of the environmental problems identified during its on-site activities. The Sampling and Analysis Plan will be executed by the Oak Ridge National Laboratory. When completed, the results will be incorporated into the Pantex Facility Environmental Survey Interim Report. The Interim Report will reflect the final determinations of the Survey for the Pantex Facility. 65 refs., 44 figs., 27 tabs.« less

Pavement testing facility : effects of tire pressure on flexible pavement response performance

DOT National Transportation Integrated Search

1989-08-01

The effects of tire pressure on flexible pavement response and performance were evaluated using data from the first phase of research at the Federal Highway Administration's Pavement Testing Facility. The Accelerated Loading Facility testing machine ...

Space transportation node - The Atrium Facility

NASA Technical Reports Server (NTRS)

Kennedy, Kriss J.

1990-01-01

A conceptual design for a space transportation node is presented with a view to the fulfilment of assembly platform support requirements associated with a lunar transportation system. This 'Atrium Facility', which will support lunar base activities before, during, and after the lunar base buildup phase, encompasses a central assembly area surrounded by hangars and workstation platforms; six permanent crewmembers will be supported, as well as four to six transient lunar and Space Shuttle crewmembers. The Atrium Facility dry mass of nearly 320,000 kg excludes cryogenic propellant stowage and the traslunar vehicle envisioned for transportation.

Amorphous silicon photovoltaic manufacturing technology, phase 2A

NASA Astrophysics Data System (ADS)

Duran, G.; Mackamul, K.; Metcalf, D.

1995-01-01

Utility Power Group (UPG), and its lower-tier subcontractor, Advanced Photovoltaic Systems, Inc. (APS) have conducted efforts in developing their manufacturing lines. UPG has focused on the automation of encapsulation and termination processes developed in Phase 1. APS has focused on completion of the encapsulation and module design tasks, while continuing the process and quality control and automation projects. The goal is to produce 55 watt (stabilized) EP50 modules in a new facility. In the APS Trenton EUREKA manufacturing facility, APS has: (1) Developed high throughput lamination procedures; (2) Optimized existing module designs; (3) Developed new module designs for architectural applications; (4) Developed enhanced deposition parameter control; (5) Designed equipment required to manufacture new EUREKA modules developed during Phase II; (6) Improved uniformity of thin-film materials deposition; and (7) Improved the stabilized power output of the APS EP50 EUREKA module to 55 watts. In the APS Fairfield EUREKA manufacturing facility, APS has: (1) Introduced the new products developed under Phase 1 into the APS Fairfield EUREKA module production line; (2) Increased the extent of automation in the production line; (3) Introduced Statistical Process Control to the module production line; and (4) Transferred-progress made in the APS Trenton facility into the APS Fairfield facility.

Enhancing Efficiency of Safeguards at Facilities that are Shutdown or Closed-Down, including those being Decommissioned

DOE Office of Scientific and Technical Information (OSTI.GOV)

Moran, B.; Stern, W.; Colley, J.

International Atomic Energy Agency (IAEA) safeguards involves verification activities at a wide range of facilities in a variety of operational phases (e.g., under construction, start-up, operating, shutdown, closed-down, and decommissioned). Safeguards optimization for each different facility type and operational phase is essential for the effectiveness of safeguards implementation. The IAEA’s current guidance regarding safeguards for the different facility types in the various lifecycle phases is provided in its Design Information Examination (DIE) and Verification (DIV) procedure. 1 Greater efficiency in safeguarding facilities that are shut down or closed down, including those being decommissioned, could allow the IAEA to use amore » greater portion of its effort to conduct other verification activities. Consequently, the National Nuclear Security Administration’s Office of International Nuclear Safeguards sponsored this study to evaluate whether there is an opportunity to optimize safeguards approaches for facilities that are shutdown or closed-down. The purpose of this paper is to examine existing safeguards approaches for shutdown and closed-down facilities, including facilities being decommissioned, and to seek to identify whether they may be optimized.« less

"Venom" of the slow loris: sequence similarity of prosimian skin gland protein and Fel d 1 cat allergen.

PubMed

Krane, Sonja; Itagaki, Yasuhiro; Nakanishi, Koji; Weldon, Paul J

2003-02-01

Bites inflicted on humans by the slow loris (Nycticebus coucang), a prosimian from Indonesia, are painful and elicit anaphylaxis. Toxins from N. coucang are thought to originate in the brachial organ, a naked, gland-laden area of skin situated on the flexor surface of the arm that is licked during grooming. We isolated a major component of the brachial organ secretions from N. coucang, an approximately 18 kDa protein composed of two 70-90 amino-acid chains linked by one or more disulfide bonds. The N-termini of these peptide chains exhibit nearly 70% sequence similarity (37% identity, chain 1; 54% identity, chain 2) with the two chains of Fel d 1, the major allergen from the domestic cat (Felis catus). The extensive sequence similarity between the brachial organ component of N. coucang and the cat allergen suggests that they exhibit immunogenic cross-reactivity. This work clarifies the chemical nature of the brachial organ exudate and suggests a possible mode of action underlying the noxious effects of slow loris bites.

Global environment facility: Independent evaluation of the pilot phase; Fondo para el medio ambiente mundial: evaluacion independiente de la etapa experimental

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1994-06-01

This study responds to a request by participants in the Global Environment Facility (GEF) for an independent evaluation of the pilot phase. It profiles the GEF, discusses its policy framework, and reviews project development procedures and the strategies and projects in each of the GEF`s four focal areas. The study concludes that fundamental changes must occur and recommends specific reforms, such as articulating more clearly the GEF`s mandate, objectives, and strategies; addressing deficiencies in meeting its global focus; improving capacities and procedures within implementing agencies for managing the portfolio; and increasing non-government organization (NGO), country and community-level participation.

Space Station Furnace Facility. Volume 2: Requirements definition and conceptual design study

NASA Technical Reports Server (NTRS)

1992-01-01

The Space Station Freedom Furnace (SSFF) Project is divided into two phases: phase 1, a definition study phase, and phase 2, a design and development phase. TBE was awarded a research study entitled, 'Space Station Furnace Facility Requirements Definition and Conceptual Design Study' on June 2, 1989. This report addresses the definition study phase only. Phase 2 is to be complete after completion of phase 1. The contract encompassed a requirements definition study and culminated in hardware/facility conceptual designs and hardware demonstration development models to test these conceptual designs. The study was divided into two parts. Part 1 (the basic part of the effort) encompassed preliminary requirements definition and assessment; conceptional design of the SSFF Core; fabrication of mockups; and preparation for the support of a conceptional design review (CoDR). Part 2 (the optional part of the effort) included detailed definition of the engineering and design requirements, as derived from the science requirements; refinement of the conceptual design of the SSFF Core; fabrication and testing of the 'breadboards' or development models; and preparation for and support of a requirements definition review.

Limited-scope probabilistic safety analysis for the Los Alamos Meson Physics Facility (LAMPF)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sharirli, M.; Rand, J.L.; Sasser, M.K.

1992-01-01

The reliability of instrumentation and safety systems is a major issue in the operation of accelerator facilities. A probabilistic safety analysis was performed or the key safety and instrumentation systems at the Los Alamos Meson Physics Facility (LAMPF). in Phase I of this unique study, the Personnel Safety System (PSS) and the Current Limiters (XLs) were analyzed through the use of the fault tree analyses, failure modes and effects analysis, and criticality analysis. Phase II of the program was done to update and reevaluate the safety systems after the Phase I recommendations were implemented. This paper provides a brief reviewmore » of the studies involved in Phases I and II of the program.« less

Limited-scope probabilistic safety analysis for the Los Alamos Meson Physics Facility (LAMPF)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sharirli, M.; Rand, J.L.; Sasser, M.K.

1992-12-01

The reliability of instrumentation and safety systems is a major issue in the operation of accelerator facilities. A probabilistic safety analysis was performed or the key safety and instrumentation systems at the Los Alamos Meson Physics Facility (LAMPF). in Phase I of this unique study, the Personnel Safety System (PSS) and the Current Limiters (XLs) were analyzed through the use of the fault tree analyses, failure modes and effects analysis, and criticality analysis. Phase II of the program was done to update and reevaluate the safety systems after the Phase I recommendations were implemented. This paper provides a brief reviewmore » of the studies involved in Phases I and II of the program.« less

International Microgravity Plasma Facility IMPF: A Multi-User Modular Research Facility for Complex Plasma Research on ISS

NASA Astrophysics Data System (ADS)

Seurig, R.; Burfeindt, J.; Castegini, R.; Griethe, W.; Hofmann, P.

2002-01-01

On March 03, 2001, the PKE-Nefedov plasma experiment was successfully put into operation on board ISS. This complex plasma experiment is the predecessor for the semi-autonomous multi-user facility IMPF (International Microgravity Plasma Facility) to be flown in 2006 with an expected operational lifetime of 10 years. IMPF is envisioned to be an international research facility for investigators in the field of multi-component plasmas containing ions, electrons, and charged microparticles. This research filed is often referred to as "complex plasmas". The actual location of IMPF on ISS is not decided yet; potential infrastructure under consideration are EXPRESS Rack, Standard Interface Rack SIR, European Drawer Rack EDR, or a to be designed custom rack infrastructure on the Russian Segment. The actual development status of the DLR funded Pre-phase B Study for IMPF will be presented. For this phase, IMPF was assumed to be integrated in an EXPRESS Rack requiring four middeck lockers with two 4-PU ISIS drawers for accommodation. Technical and operational challenges, like a 240 Mbytes/sec continuous experimental data stream for 60 minutes, will be addressed. The project was funded by the German Space Agency (DLR) and was performed in close cooperation with scientists from the Max-Planck-Institute for Extraterrestical Physics in Munich, Germany.

The LLRF System for the S-Band RF Plants of the FERMI Linac

NASA Astrophysics Data System (ADS)

Fabris, A.; Byrd, J.; D'Auria, G.; Doolittle, L.; Gelmetti, F.; Huang, G.; Jones, J.; Milloch, M.; Predonzani, M.; Ratti, A.; Rohlev, T.; Salom, A.; Serrano, C.; Stettler, M.

2016-04-01

Specifications on electron beam quality for the operation of a linac-based free-electron laser (FEL), as FERMI in Trieste (Italy), impose stringent requirements on the stability of the electromagnetic fields of the accelerating sections. These specifications can be met only with state-of-the-art low-level RF (LLRF) systems based on advanced digital technologies. Design considerations, construction, and performance results of the FERMI digital LLRF are presented in this paper. The stability requirements derived by simulations are better than 0.1% in amplitude and 0.1° S-band in phase. The system installed in the FERMI Linac S-band RF plants has met these specifications and is in operation on a 24-h basis as a user facility. Capabilities of the system allow planning for new developments that are also described here.

Effect of impurities and post-experimental purification in SAD phasing with serial femtosecond crystallography data.

PubMed

Zhang, Tao; Gu, Yuanxin; Fan, Haifu

2016-06-01

In serial crystallography (SX) with either an X-ray free-electron laser (XFEL) or synchrotron radiation as the light source, huge numbers of micrometre-sized crystals are used in diffraction data collection. For a SAD experiment using a derivative with introduced heavy atoms, it is difficult to completely exclude crystals of the native protein from the sample. In this paper, simulations were performed to study how the inclusion of native crystals in the derivative sample could affect the result of SAD phasing and how the post-experimental purification proposed by Zhang et al. [(2015), Acta Cryst. D71, 2513-2518] could be used to remove the impurities. A gadolinium derivative of lysozyme and the corresponding native protein were used in the test. Serial femtosecond crystallography (SFX) diffraction snapshots were generated by CrystFEL. SHELXC/D, Phaser, DM, ARP/wARP and REFMAC were used for automatic structure solution. It is shown that a small amount of impurities (snapshots from native crystals) in the set of derivative snapshots can strongly affect the SAD phasing results. On the other hand, post-experimental purification can efficiently remove the impurities, leading to results similar to those from a pure sample.

Installation Restoration Program. Phase 1. Records Search 15th ABW Satellite Installations, Hawaii

DTIC Science & Technology

1984-09-01

Hickam POL Storage Facilities and Pipeline The POL storage facilities remotely located from Hickam Air Force Base (AFB...airfield with less activity than nearby Wheeler and Hickam Air Force Bases . Aircraft activity was significantly reduced in the late 1940’s and the...United States Air Force to conduct the Phase I Records Search at the 15th Air Base Wing 1-2 ES ENGINEERING-SCIENCE PHASE I PHASE 11 PHASE IV

Serial Femtosecond Crystallography Opens New Avenues for Structural Biology

PubMed Central

Coe, Jesse; Fromme, Petra

2016-01-01

Free electron lasers (FELs) provide X-ray pulses in the femtosecond time domain with up to 1012 higher photon flux than synchrotrons and open new avenues for the determination of difficult to crystallize proteins, like large complexes and human membrane proteins. While the X-ray pulses are so strong that they destroy any solid material, the crystals diffract before they are destroyed. The most successful application of FELs for biology has been the method of serial femtosecond crystallography (SFX) where nano or microcrystals are delivered to the FEL beam in a stream of their mother liquid at room temperature, which ensures the replenishment of the sample before the next X-ray pulse arrives. New injector technology allows also for the delivery of crystal in lipidic cubic phases or agarose, which reduces the sample amounts for an SFX data set by two orders of magnitude. Time-resolved SFX also allows for analysis of the dynamics of biomolecules, the proof of principle being recently shown for light-induced reactions in photosystem II and photoactive yellow protein. An SFX data sets consist of thousands of single crystal snapshots in random orientations, which can be analyzed now “on the fly” by data analysis programs specifically developed for SFX, but de-novo phasing is still a challenge, that might be overcome by two-color experiments or phasing by shape transforms. PMID:26786767

Final report on Weeks Island Monitoring Phase : 1999 through 2004.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ehgartner, Brian L.; Munson, Darrell Eugene

2005-05-01

This Final Report on the Monitoring Phase of the former Weeks Island Strategic Petroleum Reserve crude oil storage facility details the results of five years of monitoring of various surface accessible quantities at the decommissioned facility. The Weeks Island mine was authorized by the State of Louisiana as a Strategic Petroleum Reserve oil storage facility from 1979 until decommissioning of the facility in 1999. Discovery of a sinkhole over the facility in 1992 with freshwater inflow to the facility threatened the integrity of the oil storage and led to the decision to remove the oil, fill the chambers with brine,more » and decommission the facility. Thereafter, a monitoring phase, by agreement between the Department of Energy and the State, addressed facility stability and environmental concerns. Monitoring of the surface ground water and the brine of the underground chambers from the East Fill Hole produced no evidence of hydrocarbon contamination, which suggests that any unrecovered oil remaining in the underground chambers has been contained. Ever diminishing progression of the initial major sinkhole, and a subsequent minor sinkhole, with time was verification of the response of sinkholes to filling of the facility with brine. Brine filling of the facility ostensively eliminates any further growth or new formation from freshwater inflow. Continued monitoring of sinkhole response, together with continued surface surveillance for environmental problems, confirmed the intended results of brine pressurization. Surface subsidence measurements over the mine continued throughout the monitoring phase. And finally, the outward flow of brine was monitored as a measure of the creep closure of the mine chambers. Results of each of these monitoring activities are presented, with their correlation toward assuring the stability and environmental security of the decommissioned facility. The results suggest that the decommissioning was successful and no contamination of

Mode-Locked Multichromatic X-Rays in a Seeded Free-Electron Laser for Single-Shot X-Ray Spectroscopy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xiang, Dao; Ding, Yuantao; Raubenheimer, Tor

2012-05-10

We present the promise of generating gigawatt mode-locked multichromatic x rays in a seeded free-electron laser (FEL). We show that, by using a laser to imprint periodic modulation in electron beam phase space, a single-frequency coherent seed can be amplified and further translated to a mode-locked multichromatic output in an FEL. With this configuration the FEL output consists of a train of mode-locked ultrashort pulses which span a wide frequency gap with a series of equally spaced sharp lines. These gigawatt multichromatic x rays may potentially allow one to explore the structure and dynamics of a large number of atomicmore » states simultaneously. The feasibility of generating mode-locked x rays ranging from carbon K edge ({approx}284 eV) to copper L{sub 3} edge ({approx}931 eV) is confirmed with numerical simulation using the realistic parameters of the linac coherent light source (LCLS) and LCLS-II. We anticipate that the mode-locked multichromatic x rays in FELs may open up new opportunities in x-ray spectroscopy (i.e. resonant inelastic x-ray scattering, time-resolved scattering and spectroscopy, etc.).« less

The 400W at 1.8K Test Facility at CEA-Grenoble

NASA Astrophysics Data System (ADS)

Roussel, P.; Girard, A.; Jager, B.; Rousset, B.; Bonnay, P.; Millet, F.; Gully, P.

2006-04-01

A new test facility with a cooling capacity respectively of 400W at 1.8K or 800W at 4.5K, is now under nominal operation in SBT (Low Temperature Department) at CEA Grenoble. It has been recently used for thermohydraulic studies of two phase superfluid helium in autumn 2004. In the near future, this test bench will allow: - to test industrial components at 1.8K (magnets, cavities of accelerators) - to continue the present studies on thermohydraulics of two phase superfluid helium - to develop and simulate new cooling loops for ITER Cryogenics, and other applications such as high Reynolds number flows This new facility consists of a cold box connected to a warm compressor station (one subatmospheric oil ring pump in series with two screw compressors). The cold box, designed by AIR LIQUIDE, comprises two centrifugal cold compressors, a cold turbine, a wet piston expander, counter flow heat exchangers and two phase separators at 4.5K and 1.8K. The new facility uses a Programmable Logic Controller (PLC) connected to a bus for the measurements. The design is modular and will allow the use of saturated fluid flow (two phase flow at 1.8K or 4.5K) or single phase fluid forced flow. Experimental results and cooling capacity in different operation modes are detailed.

Universal Test Facility

NASA Technical Reports Server (NTRS)

Laughery, Mike

1994-01-01

A universal test facility (UTF) for Space Station Freedom is developed. In this context, universal means that the experimental rack design must be: automated, highly marketable, and able to perform diverse microgravity experiments according to NASA space station requirements. In order to fulfill these broad objectives, the facility's customers, and their respective requirements, are first defined. From these definitions, specific design goals and the scope of the first phase of this project are determined. An examination is first made into what types of research are most likely to make the UTF marketable. Based on our findings, the experiments for which the UTF would most likely be used included: protein crystal growth, hydroponics food growth, gas combustion, gallium arsenide crystal growth, microorganism development, and cell encapsulation. Therefore, the UTF is designed to fulfill all of the major requirements for the experiments listed above. The versatility of the design is achieved by taking advantage of the many overlapping requirements presented by these experiments.

Universal Test Facility

NASA Astrophysics Data System (ADS)

Laughery, Mike

A universal test facility (UTF) for Space Station Freedom is developed. In this context, universal means that the experimental rack design must be: automated, highly marketable, and able to perform diverse microgravity experiments according to NASA space station requirements. In order to fulfill these broad objectives, the facility's customers, and their respective requirements, are first defined. From these definitions, specific design goals and the scope of the first phase of this project are determined. An examination is first made into what types of research are most likely to make the UTF marketable. Based on our findings, the experiments for which the UTF would most likely be used included: protein crystal growth, hydroponics food growth, gas combustion, gallium arsenide crystal growth, microorganism development, and cell encapsulation. Therefore, the UTF is designed to fulfill all of the major requirements for the experiments listed above. The versatility of the design is achieved by taking advantage of the many overlapping requirements presented by these experiments.

3S (Safeguards, Security, Safety) based pyroprocessing facility safety evaluation plan

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ku, J.H.; Choung, W.M.; You, G.S.

The big advantage of pyroprocessing for the management of spent fuels against the conventional reprocessing technologies lies in its proliferation resistance since the pure plutonium cannot be separated from the spent fuel. The extracted materials can be directly used as metal fuel in a fast reactor, and pyroprocessing reduces drastically the volume and heat load of the spent fuel. KAERI has implemented the SBD (Safeguards-By-Design) concept in nuclear fuel cycle facilities. The goal of SBD is to integrate international safeguards into the entire facility design process since the very beginning of the design phase. This paper presents a safety evaluationmore » plan using a conceptual design of a reference pyroprocessing facility, in which 3S (Safeguards, Security, Safety)-By-Design (3SBD) concept is integrated from early conceptual design phase. The purpose of this paper is to establish an advanced pyroprocessing hot cell facility design concept based on 3SBD for the successful realization of pyroprocessing technology with enhanced safety and proliferation resistance.« less

Three dimensional radiation fields in free electron lasers using Lienard-Wiechert fields

DOE Office of Scientific and Technical Information (OSTI.GOV)

Elias, L.R.; Gallardo, J.

1981-10-28

In a free electron laser a relativistic electron beam is bunched under the action of the ponderomotive potential and is forced to radiate in close phase with the input wave. Until recently, most theories of the FEL have dealt solely with electron beams of infinite transverse dimension radiating only one-dimensional E.M. waves (plane waves). Although these theories describe accurately the dynamics of the electrons during the FEL interaction process, neither the three dimensional nature of the radiated fields nor its non-monochromatic features can be properly studied by them. As a result of this, very important practical issues such as themore » gain per gaussian-spherical optical mode in a free electron laser have not been well addressed, except through a one dimensional field model in which a filling factor describes crudely the coupling of the FEL induced field to the input field.« less

Analysis and Modeling of a Two-Phase Jet Pump of a Flow Boiling Test Facility for Aerospace Applications

NASA Technical Reports Server (NTRS)

Sherif, S. A.; Steadham, Justin M.

1996-01-01

research known to the authors apart from that of Anand (1992) which accounted for condensation shocks. One of the objectives of this research effort is to develop a comprehensive model in which the effects of phase slip and inter-phase heat transfer as well as the wall friction and shock waves are accounted for. While this modeling effort is predominantly analytical in nature and is primarily intended to provide a parametric understanding of the jet pump performance under different operating scenarios, another parallel effort employing a commercial CFD code is also implemented. The latter effort is primarily intended to model an axisymmetric counterpart of the problem in question. The viability of using the CFD code to model a two-phase flow jet pump will be assessed by attempting to recreate some of the existing performance data of similar jet pumps. The code will eventually be used to generate the jet pump performance characteristics of several scenarios involving jet pump geometries as well as flow regimes in order to be able to determine an optimum design which would be suitable for a two-phase flow boiling test facility at NASA-Marshall. Because of the extensive nature of the analytical model developed, the following section will only provide very brief highlights of it, while leaving the details to a more complete report submitted to the NASA colleague. This report will also contain some of the simulation results obtained using the CFD code.

Medical care capabilities for Space Station Freedom: A phase approach

NASA Technical Reports Server (NTRS)

Doarn, C. R.; Lloyd, C. W.

1992-01-01

As a result of Congressional mandate Space Station Freedom (SSF) was restructured. This restructuring activity has affected the capabilities for providing medical care on board the station. This presentation addresses the health care facility to be built and used on the orbiting space station. This unit, named the Health Maintenance Facility (HMF) is based on and modeled after remote, terrestrial medical facilities. It will provide a phased approach to health care for the crews of SSF. Beginning with a stabilization and transport phase, HMF will expand to provide the most advanced state of the art therapeutic and diagnostic capabilities. This presentation details the capabilities of such a phased HMF. As Freedom takes form over the next decade there will be ever-increasing engineering and scientific developmental activities. The HMF will evolve with this process until it eventually reaches a mature, complete stand-alone health care facility that provides a foundation to support interplanetary travel. As man's experience in space continues to grow so will the ability to provide advanced health care for Earth-orbital and exploratory missions as well.

Analyses in support of risk-informed natural gas vehicle maintenance facility codes and standards :

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ekoto, Isaac W.; Blaylock, Myra L.; LaFleur, Angela Christine

2014-03-01

Safety standards development for maintenance facilities of liquid and compressed gas fueled large-scale vehicles is required to ensure proper facility design and operation envelopes. Standard development organizations are utilizing risk-informed concepts to develop natural gas vehicle (NGV) codes and standards so that maintenance facilities meet acceptable risk levels. The present report summarizes Phase I work for existing NGV repair facility code requirements and highlights inconsistencies that need quantitative analysis into their effectiveness. A Hazardous and Operability study was performed to identify key scenarios of interest. Finally, scenario analyses were performed using detailed simulations and modeling to estimate the overpressure hazardsmore » from HAZOP defined scenarios. The results from Phase I will be used to identify significant risk contributors at NGV maintenance facilities, and are expected to form the basis for follow-on quantitative risk analysis work to address specific code requirements and identify effective accident prevention and mitigation strategies.« less

A modular and compact portable mini-endstation for high-precision, high-speed fixed target serial crystallography at FEL and synchrotron sources

DOE PAGES

Sherrell, Darren A.; Foster, Andrew J.; Hudson, Lee; ...

2015-01-01

The design and implementation of a compact and portable sample alignment system suitable for use at both synchrotron and free-electron laser (FEL) sources and its performance are described. The system provides the ability to quickly and reliably deliver large numbers of samples using the minimum amount of sample possible, through positioning of fixed target arrays into the X-ray beam. The combination of high-precision stages, high-quality sample viewing, a fast controller and a software layer overcome many of the challenges associated with sample alignment. A straightforward interface that minimizes setup and sample changeover time as well as simplifying communication with themore » stages during the experiment is also described, together with an intuitive naming convention for defining, tracking and locating sample positions. Lastly, the setup allows the precise delivery of samples in predefined locations to a specific position in space and time, reliably and simply.« less

Laser-plasma accelerator-based single-cycle attosecond undulator source

NASA Astrophysics Data System (ADS)

Tibai, Z.; Tóth, Gy.; Nagyváradi, A.; Sharma, A.; Mechler, M. I.; Fülöp, J. A.; Almási, G.; Hebling, J.

2018-06-01

Laser-plasma accelerators (LPAs), producing high-quality electron beams, provide an opportunity to reduce the size of free-electron lasers (FELs) to only a few meters. A complete system is proposed here, which is based on FEL technology and consists of an LPA, two undulators, and other magnetic devices. The system is capable to generate carrier-envelope phase stable attosecond pulses with engineered waveform. Pulses with up to 60 nJ energy and 90-400 attosecond duration in the 30-120 nm wavelength range are predicted by numerical simulation. These pulses can be used to investigate ultrafast field-driven electron dynamics in matter.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Flechsig, U.; Follath, R.; Reiche, S.

PHASE is a software tool for physical optics simulation based on the stationary phase approximation method. The code is under continuous development since about 20 years and has been used for instance for fundamental studies and ray tracing of various beamlines at the Swiss Light Source. Along with the planning for SwissFEL a new hard X-ray free electron laser under construction, new features have been added to permit practical performance predictions including diffraction effects which emerge with the fully coherent source. We present the application of the package on the example of the ARAMIS 1 beamline at SwissFEL. The X-raymore » pulse calculated with GENESIS and given as an electrical field distribution has been propagated through the beamline to the sample position. We demonstrate the new features of PHASE like the treatment of measured figure errors, apertures and coatings of the mirrors and the application of Fourier optics propagators for free space propagation.« less

Femtosecond timing distribution and control for next generation accelerators and light sources

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, Li -Jin

Femtosecond Timing Distribution At LCLS Free-electron-lasers (FEL) have the capability of producing high photon flux from the IR to the hard x-ray wavelength range and to emit femtosecond and eventually even attosecond pulses. This makes them an ideal tool for fundamental as well as applied re-search. Timing precision at the Stanford Linear Coherent Light Source (LCLS) between the x-ray FEL (XFEL) and ultrafast optical lasers is currently no better than 100 fs RMS. Ideally this precision should be much better and could be limited only by the x-ray pulse duration, which can be as short as a few femtoseconds. Anmore » increasing variety of science problems involving electron and nuclear dynamics in chemical and material systems will become accessible as the timing improves to a few femtoseconds. Advanced methods of electron beam conditioning or pulse injection could allow the FEL to achieve pulse durations less than one femtosecond. The objective of the work described in this proposal is to set up an optical timing distribution system based on mode locked Erbium doped fiber lasers at LCLS facility to improve the timing precision in the facility and allow time stamping with a 10 fs precision. The primary commercial applications for optical timing distributions systems are seen in the worldwide accelerator facilities and next generation light sources community. It is reasonable to expect that at least three major XFELs will be built in the next decade. In addition there will be up to 10 smaller machines, such as FERMI in Italy and Maxlab in Sweden, plus the market for upgrading already existing facilities like Jefferson Lab. The total market is estimated to be on the order of a 100 Million US Dollars. The company owns the exclusive rights to the IP covering the technology enabling sub-10 fs synchronization systems. Testing this technology, which has set records in a lab environment, at LCLS, hence in a real world scenario, is an important corner stone of bringing the

Upgrades at the Duke Free Electron Laser Laboratory

NASA Astrophysics Data System (ADS)

Howell, Calvin R.

2004-11-01

Major upgrades to the storage-ring based photon sources at the Duke Free Electron Laser Laboratory (DFELL) are underway. The photon sources at the DFELL are well suited for research in the areas of medicine, biophysics, accelerator physics, nuclear physics and material science. These upgrades, which will be completed by the summer 2006, will significantly enhance the capabilities of the ultraviolet (UV) free-electron laser (FEL) and the high intensity gamma-ray source (HIGS). The HIGS is a relatively new research facility at the DFELL that is operated jointly by the DFELL and the Triangle Universities Nuclear Laboratory. The gamma-ray beam is produced by Compton back scattering of the UV photons inside the FEL optical cavity off the circulating electrons in the storage ring. The gamma-ray beam is 100% polarized and its energy resolution is selected by collimation. The capabilities of the upgraded facility will be described, the status of the upgrades will be summarized, and the proposed first-generation research program at HIGS will be presented.

Modeling of a Two-Phase Jet Pump with Phase Change, Shocks and Temperature-Dependent Properties

NASA Technical Reports Server (NTRS)

Sherif, S. A.

1998-01-01

One of the primary motivations behind this work is the attempt to understand the physics of a two-phase jet pump which constitutes part of a flow boiling test facility at NASA-Marshall. The flow boiling apparatus is intended to provide data necessary to design highly efficient two-phase thermal control systems for aerospace applications. The facility will also be capable of testing alternative refrigerants and evaluate their performance using various heat exchangers with enhanced surfaces. The test facility is also intended for use in evaluating single-phase performance of systems currently using CFC refrigerants. Literature dealing with jet pumps is abundant and covers a very wide array of application areas. Example application areas include vacuum pumps which are used in the food industry, power station work, and the chemical industry; ejector systems which have applications in the aircraft industry as cabin ventilators and for purposes of jet thrust augmentation; jet pumps which are used in the oil industry for oil well pumping; and steam-jet ejector refrigeration, to just name a few. Examples of work relevant to this investigation includes those of Fairuzov and Bredikhin (1995). While past researchers have been able to model the two-phase flow jet pump using the one-dimensional assumption with no shock waves and no phase change, there is no research known to the author apart from that of Anand (1992) who was able to account for condensation shocks. Thus, one of the objectives of this work is to model the dynamics of fluid interaction between a two-phase primary fluid and a subcooled liquid secondary fluid which is being injected employing atomizing spray injectors. The model developed accounts for phase transformations due to expansion, compression, and mixing. It also accounts for shock waves developing in the different parts of the jet pump as well as temperature and pressure dependencies of the fluid properties for both the primary two-phase mixture and the

Irradiation setup at the U-120M cyclotron facility

NASA Astrophysics Data System (ADS)

Křížek, F.; Ferencei, J.; Matlocha, T.; Pospíšil, J.; Príbeli, P.; Raskina, V.; Isakov, A.; Štursa, J.; Vaňát, T.; Vysoká, K.

2018-06-01

This paper describes parameters of the proton beams provided by the U-120M cyclotron and the related irradiation setup at the open access irradiation facility at the Nuclear Physics Institute of the Czech Academy of Sciences. The facility is suitable for testing radiation hardness of various electronic components. The use of the setup is illustrated by a measurement of an error rate for errors caused by Single Event Transients in an SRAM-based Xilinx XC3S200 FPGA. This measurement provides an estimate of a possible occurrence of Single Event Transients. Data suggest that the variation of error rate of the Single Event Effects for different clock phase shifts is not significant enough to use clock phase alignment with the beam as a fault mitigation technique.

Facility Composer (Trademark) and PACES (Trademark) Integration: Development of an XML Interface Based on Industry Foundation Classes

DTIC Science & Technology

2007-11-01

Engineer- ing Research Laboratory is currently developing a set of facility ‘architec- tural’ programming tools , called Facility ComposerTM (FC). FC...requirements in the early phases of project development. As the facility program, crite- ria, and requirements are chosen, these tools populate the IFC...developing a set of facility “ar- chitectural” programming tools , called Facility Composer (FC), to support the capture and tracking of facility criteria

RCRA facility investigation and risk assessment, McAlester Army Ammunition Plant, McAlester, Oklahoma. Supplemental phase 2 RFI report, Solid Waste Management Units 32 and 33

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1994-11-30

This report presents the results of the Supplemental Phase 2 Resource Conservation and Recovery Act (RCRA) Facility Investigation (RFI) conducted for Solid Waste Management Units (SWMU) Number 32 and Number 33 at McAlester Army Ammunition Plant (MCAAP). The supplemental action of the RFI was conducted as part of the actions required in connection with the application for a RCRA permit for the management of hazardous waste at MCAAP. The objective of this Supplemental Phase 2 RFI is to collect and analyze soil samples from Solid Waste Management Unit (SWMU) 32 and SWMU 33 for dioxins/dibenzofurans. The purpose of this reportmore » is to describe the procedures used to perform the Supplemental Phase 2 RFI to present and assess the results obtained in terms of the nature and extent of any contamination found, to present the results of human health and ecological risk assessments, and to recommend future actions.« less

Bendable Focusing X-Ray Optics for the ALS and the LCLS/FEL: Design, Metrology, and Performance

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yashchuk, V. V.; Yuan, S.; Baker, S.

2010-06-02

We review the recent development of bendable x-ray optics used for focusing of beams of soft and hard x-rays at the Advanced Light Source (ALS) at Lawrence Berkeley National Laboratory and at the Linac Coherent Light Source (LCLS) x-ray free electron laser (FEL) at the Stanford Linear Accelerator Center (SLAC) National Accelerator Laboratory. For simultaneous focusing in the tangential and sagittal directions, two elliptically cylindrical reflecting elements, a Kirkpatrick-Baez (KB) pair, are used. Because fabrication of elliptical surfaces is complicated, the cost of directly fabricated tangential elliptical cylinders is often prohibitive. Moreover, such optics cannot be easily readjusted for usemore » in multiple, different experimental arrangements, e.g. at different focal distances. This is in contrast to flat optics that are simpler to manufacture and easier to measure by conventional interferometry. The tangential figure of a flat substrate is changed by placing torques (couples) at each end. Depending on the applied couples, one can tune the shape close to a desired tangential cylinder, ellipse or parabola. We review the nature of the bending, requirements and approaches to the mechanical design, describe original optical and at-wavelength techniques for optimal tuning of bendable optics and alignment on the beamline, and provide beamline performance of the bendable optics used for sub-micro and nano focusing of soft x-rays.« less

High-Lift Flight Tunnel - Phase II Report. Phase 2 Report

NASA Technical Reports Server (NTRS)

Lofftus, David; Lund, Thomas; Rote, Donald; Bushnell, Dennis M. (Technical Monitor)

2000-01-01

The High-Lift Flight Tunnel (HiLiFT) concept is a revolutionary approach to aerodynamic ground testing. This concept utilizes magnetic levitation and linear motors to propel an aerodynamic model through a tube containing a quiescent test medium. This medium (nitrogen) is cryogenic and pressurized to achieve full flight Reynolds numbers higher than any existing ground test facility world-wide for the range of 0.05 to 0.50 Mach. The results of the Phase II study provide excellent assurance that the HiLiFT concept will provide a valuable low-speed, high Reynolds number ground test facility. The design studies concluded that the HiLiFT facility is feasible to build and operate and the analytical studies revealed no insurmountable difficulties to realizing a practical high Reynolds number ground test facility. It was determined that a national HiLiFT facility, including development, would cost approximately $400M and could be operational by 2013 if fully funded. Study participants included National Aeronautics and Space Administration Langley Research Center as the Program Manager and MSE Technology Applications, Inc., (MSE) of Butte, Montana as the prime contractor and study integrator. MSE#s subcontractors included the University of Texas at Arlington for aerodynamic analyses and the Argonne National Laboratory for magnetic levitation and linear motor technology support.

Space Station Furnace Facility Preliminary Project Implementation Plan (PIP). Volume 2, Appendix 2

NASA Technical Reports Server (NTRS)

Perkey, John K.

1992-01-01

The Space Station Furnace Facility (SSFF) is an advanced facility for materials research in the microgravity environment of the Space Station Freedom and will consist of Core equipment and various sets of Furnace Module (FM) equipment in a three-rack configuration. This Project Implementation Plan (PIP) document was developed to satisfy the requirements of Data Requirement Number 4 for the SSFF study (Phase B). This PIP shall address the planning of the activities required to perform the detailed design and development of the SSFF for the Phase C/D portion of this contract.

X-ray Cryogenic Facility (XRCF) Handbook

NASA Technical Reports Server (NTRS)

Kegley, Jeffrey R.

2016-01-01

The X-ray & Cryogenic Facility (XRCF) Handbook is a guide for planning operations at the facility. A summary of the capabilities, policies, and procedures is provided to enhance project coordination between the facility user and XRCF personnel. This handbook includes basic information that will enable the XRCF to effectively plan and support test activities. In addition, this handbook describes the facilities and systems available at the XRCF for supporting test operations. 1.2 General Facility Description The XRCF was built in 1989 to meet the stringent requirements associated with calibration of X-ray optics, instruments, and telescopes and was subsequently modified in 1999 & 2005 to perform the challenging cryogenic verification of Ultraviolet, Optical, and Infrared mirrors. These unique and premier specialty capabilities, coupled with its ability to meet multiple generic thermal vacuum test requirements for large payloads, make the XRCF the most versatile and adaptable space environmental test facility in the Agency. XRCF is also recognized as the newest, most cost effective, most highly utilized facility in the portfolio and as one of only five NASA facilities having unique capabilities. The XRCF is capable of supporting and has supported missions during all phases from technology development to flight verification. Programs/projects that have benefited from XRCF include Chandra, Solar X-ray Imager, Hinode, and James Webb Space Telescope. All test programs have been completed on-schedule and within budget and have experienced no delays due to facility readiness or failures. XRCF is currently supporting Strategic Astrophysics Technology Development for Cosmic Origins. Throughout the years, XRCF has partnered with and continues to maintain positive working relationships with organizations such as ATK, Ball Aerospace, Northrop Grumman Aerospace, Excelis (formerly Kodak/ITT), Smithsonian Astrophysical Observatory, Goddard Space Flight Center, University of Alabama

Space Station Furnace Facility. Volume 1: Requirements definition and conceptual design study, executive summary

NASA Technical Reports Server (NTRS)

1992-01-01

The Space Station Freedom Furnace (SSFF) Study was awarded on June 2, 1989, to Teledyne Brown Engineering (TBE) to define an advanced facility for materials research in the microgravity environment of Space Station Freedom (SSF). The SSFF will be designed for research in the solidification of metals and alloys, the crystal growth of electronic and electro-optical materials, and research in glasses and ceramics. The SSFF is one of the first 'facility' class payloads planned by the Microgravity Science and Applications Division (MSAD) of the Office of Space Science and Applications of NASA Headquarters. This facility is planned for early deployment during man-tended operations of the SSF with continuing operations through the Permanently Manned Configuration (PMC). The SSFF will be built around a general 'Core' facility which provides common support functions not provided by SSF, common subsystems which are best centralized, and common subsystems which are best distributed with each experiment module. The intent of the facility approach is to reduce the overall cost associated with implementing and operating a variety of experiments. This is achieved by reducing the launch mass and simplifying the hardware development and qualification processes associated with each experiment. The Core will remain on orbit and will require only periodic maintenance and upgrading while new Furnace Modules, samples, and consumables are developed, qualified, and transported to the SSF. The SSFF Study was divided into two phases: phase 1, a definition study phase, and phase 2, a design and development phase. The definition phase 1 is addressed. Phase 1 was divided into two parts. In the first part, the basic part of the effort, covered the preliminary definition and assessment of requirements; conceptual design of the SSFF; fabrication of mockups; and the preparation for and support of the Conceptual Design Review (CoDR). The second part, the option part, covered requirements update and

Preliminary study for a numerical aerodynamic simulation facility. Phase 1: Extension

NASA Technical Reports Server (NTRS)

Lincoln, N. R.

1978-01-01

Functional requirements and preliminary design data were identified for use in the design of all system components and in the construction of a facility to perform aerodynamic simulation for airframe design. A skeleton structure of specifications for the flow model processor and monitor, the operating system, and the language and its compiler is presented.

Transportation informatics : an image analysis system for managing transportation facilities - phase II.

DOT National Transportation Integrated Search

2012-02-01

One of the most important tasks in maintaining transportation facilities such as highways : and streets is the evaluation of the existing condition. Visual evaluation by human : inspectors is subjective in nature, therefore has issues of consistency ...

Safe, Cost Effective Management of Inactive Facilities at the Savannah River Site

DOE Office of Scientific and Technical Information (OSTI.GOV)

Austin, W. E.; Yannitell, D. M.; Freeman, D. W.

The Savannah River Site is part of the U.S. Department of Energy complex. It was constructed during the early 1950s to produce basic materials (such as plutonium-239 and tritium) used in the production of nuclear weapons. The 310-square-mile site is located in South Carolina, about 12 miles south of Aiken, South Carolina, and about 15 miles southeast of Augusta, Georgia. Savannah River Site (SRS) has approximately 200 facilities identified as inactive. These facilities range in size and complexity from large nuclear reactors to small storage buildings. These facilities are located throughout the site including three reactor areas, the heavy watermore » plant area, the manufacturing area, and other research and support areas. Unlike DOE Closure Sites such as Hanford and Rocky Flats, SRS is a Project Completion Site with continuing missions. As facilities complete their defined mission, they are shutdown and transferred from operations to the facility disposition program. At the SRS, Facilities Decontamination and Decommissioning (FDD) personnel manage the disposition phase of a inactive facility's life cycle in a manner that minimizes life cycle cost without compromising (1) the health or safety of workers and the public or (2) the quality of the environment. The disposition phase begins upon completion of operations shutdown and extends through establishing the final end-state. FDD has developed innovative programs to manage their responsibilities within a constrained budget.« less

Calibration methods and performance evaluation for pnCCDs in experiments with FEL radiation

NASA Astrophysics Data System (ADS)

Kimmel, N.; Andritschke, R.; Englert, L.; Epp, S.; Hartmann, A.; Hartmann, R.; Hauser, G.; Holl, P.; Ordavo, I.; Richter, R.; Strüder, L.; Ullrich, J.

2011-06-01

Measurement campaigns of the Max-Planck Advanced Study Group (ASG) in cooperation with the Center for Free Electron Laser Science (CFEL) at DESY-FLASH and SLAC-LCLS have established pnCCDs as universal photon imaging spectrometers in the energy range from 90 eV to 2 keV. In the CFEL-ASG multi purpose chamber (CAMP), pnCCD detector modules are an integral part of the design with the ability to detect photons at very small scattering angles. In order to fully exploit the spectroscopic and intensity imaging capability of pnCCDs, it is essentially important to translate the unprocessed raw data into units of photon counts for any given position on the detection area. We have studied the performance of pnCCDs in FEL experiments and laboratory test setups for the range of signal intensities from a few X-ray photons per signal frame to 100 or more photons with an energy of 2 keV per pixel. Based on these measurement results, we were able to characterize the response of pnCCDs over the experimentally relevant photon energy and intensity range. The obtained calibration results are directly relevant for the physics data analysis. The accumulated knowledge of the detector performance was implemented in guidelines for detector calibration methods which are suitable for the specific requirements in photon science experiments at Free Electron Lasers. We discuss the achievable accuracy of photon energy and photon count measurements before and after the application of calibration data. Charge spreading due to illumination of small spots with high photon rates is discussed with respect to the charge handling capacity of a pixel and the effect of the charge spreading process on the resulting signal patterns.

Electronic and atomic kinetics in solids irradiated with free-electron lasers or swift-heavy ions

NASA Astrophysics Data System (ADS)

Medvedev, N.; Volkov, A. E.; Ziaja, B.

2015-12-01

In this brief review we discuss the transient processes in solids under irradiation with femtosecond X-ray free-electron-laser (FEL) pulses and swift-heavy ions (SHI). Both kinds of irradiation produce highly excited electrons in a target on extremely short timescales. Transfer of the excess electronic energy into the lattice may lead to observable target modifications such as phase transitions and damage formation. Transient kinetics of material excitation and relaxation under FEL or SHI irradiation are comparatively discussed. The same origin for the electronic and atomic relaxation in both cases is demonstrated. Differences in these kinetics introduced by the geometrical effects (μm-size of a laser spot vs nm-size of an ion track) and initial irradiation (photoabsorption vs an ion impact) are analyzed. The basic mechanisms of electron transport and electron-lattice coupling are addressed. Appropriate models and their limitations are presented. Possibilities of thermal and nonthermal melting of materials under FEL and SHI irradiation are discussed.

Designs and numerical calculations for echo-enabled harmonic generation at very high harmonics

NASA Astrophysics Data System (ADS)

Penn, G.; Reinsch, M.

2011-09-01

The echo-enabled harmonic generation (EEHG) scheme for driving an FEL using two seeded energy modulations at much longer wavelengths than the output wavelength is a promising concept for future seeded FELs. There are many competing requirements in the design of an EEHG beamline which need careful optimization. Furthermore, revised simulation tools and methods are necessary because of both the high harmonic numbers simulated and the complicated nature of the phase space manipulations which are intrinsic to the scheme. This paper explores the constraints on performance and the required tolerances for reaching wavelengths well below 1/100th of that of the seed lasers, and describes some of the methodology for designing such a beamline. Numerical tools, developed both for the GENESIS and GINGER FEL codes, are presented and used here for more accurate study of the scheme beyond a time-averaged model. In particular, the impact of the local structure in peak current and bunching, which is an inherent part of the EEHG scheme, is evaluated.

National Institutes of Health-Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities.

PubMed

Ricordi, Camillo; Goldstein, Julia S; Balamurugan, A N; Szot, Gregory L; Kin, Tatsuya; Liu, Chengyang; Czarniecki, Christine W; Barbaro, Barbara; Bridges, Nancy D; Cano, Jose; Clarke, William R; Eggerman, Thomas L; Hunsicker, Lawrence G; Kaufman, Dixon B; Khan, Aisha; Lafontant, David-Erick; Linetsky, Elina; Luo, Xunrong; Markmann, James F; Naji, Ali; Korsgren, Olle; Oberholzer, Jose; Turgeon, Nicole A; Brandhorst, Daniel; Chen, Xiaojuan; Friberg, Andrew S; Lei, Ji; Wang, Ling-Jia; Wilhelm, Joshua J; Willits, Jamie; Zhang, Xiaomin; Hering, Bernhard J; Posselt, Andrew M; Stock, Peter G; Shapiro, A M James; Chen, Xiaojuan

2016-11-01

Eight manufacturing facilities participating in the National Institutes of Health-sponsored Clinical Islet Transplantation (CIT) Consortium jointly developed and implemented a harmonized process for the manufacture of allogeneic purified human pancreatic islet (PHPI) product evaluated in a phase 3 trial in subjects with type 1 diabetes. Manufacturing was controlled by a common master production batch record, standard operating procedures that included acceptance criteria for deceased donor organ pancreata and critical raw materials, PHPI product specifications, certificate of analysis, and test methods. The process was compliant with Current Good Manufacturing Practices and Current Good Tissue Practices. This report describes the manufacturing process for 75 PHPI clinical lots and summarizes the results, including lot release. The results demonstrate the feasibility of implementing a harmonized process at multiple facilities for the manufacture of a complex cellular product. The quality systems and regulatory and operational strategies developed by the CIT Consortium yielded product lots that met the prespecified characteristics of safety, purity, potency, and identity and were successfully transplanted into 48 subjects. No adverse events attributable to the product and no cases of primary nonfunction were observed. © 2016 by the American Diabetes Association.

National Institutes of Health–Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities

PubMed Central

Balamurugan, A.N.; Szot, Gregory L.; Kin, Tatsuya; Liu, Chengyang; Czarniecki, Christine W.; Barbaro, Barbara; Bridges, Nancy D.; Cano, Jose; Clarke, William R.; Eggerman, Thomas L.; Hunsicker, Lawrence G.; Kaufman, Dixon B.; Khan, Aisha; Lafontant, David-Erick; Linetsky, Elina; Luo, Xunrong; Markmann, James F.; Naji, Ali; Korsgren, Olle; Oberholzer, Jose; Turgeon, Nicole A.; Brandhorst, Daniel; Chen, Xiaojuan; Friberg, Andrew S.; Lei, Ji; Wang, Ling-jia; Wilhelm, Joshua J.; Willits, Jamie; Zhang, Xiaomin; Hering, Bernhard J.; Posselt, Andrew M.; Stock, Peter G.; Shapiro, A.M. James

2016-01-01

Eight manufacturing facilities participating in the National Institutes of Health–sponsored Clinical Islet Transplantation (CIT) Consortium jointly developed and implemented a harmonized process for the manufacture of allogeneic purified human pancreatic islet (PHPI) product evaluated in a phase 3 trial in subjects with type 1 diabetes. Manufacturing was controlled by a common master production batch record, standard operating procedures that included acceptance criteria for deceased donor organ pancreata and critical raw materials, PHPI product specifications, certificate of analysis, and test methods. The process was compliant with Current Good Manufacturing Practices and Current Good Tissue Practices. This report describes the manufacturing process for 75 PHPI clinical lots and summarizes the results, including lot release. The results demonstrate the feasibility of implementing a harmonized process at multiple facilities for the manufacture of a complex cellular product. The quality systems and regulatory and operational strategies developed by the CIT Consortium yielded product lots that met the prespecified characteristics of safety, purity, potency, and identity and were successfully transplanted into 48 subjects. No adverse events attributable to the product and no cases of primary nonfunction were observed. PMID:27465220

Professional burnout syndrome among correctional facility officers.

PubMed

Harizanova, Stanislava N; Tarnovska, Tanya H

2013-01-01

Correctional facilities present unique work places--the employees there work in tough, demanding and hazardous working conditions, in real life-threatening environment, subjected to physical and mental fatigue, risk of infectious diseases, work in shifts, with inadequate pay, etc. The aim of this study was to find the prevalence and level of burnout syndrome among employees working in the District Prison of the town of Plovdiv. The study included all employees that had direct contact with the inmates in the prison. We recruited 106 employees that participated in the study anonymously and voluntarily. The main instrument we used was the questionnaire designed according to the methods developed by V. Boiko, which allows identification of professional burnout syndrome in its three phases with four symptoms in each of the phases. We found a high prevalence of burnout syndrome among the staff in the District Prison in Plovdiv (74.53%). All three phases of burnout were found to have a high prevalence rate--the stress phase: 48.11%, the resistance phase: 66.98%, the exhaustion phase: 41.51%. The rank in the service hierarchy was found to be a predictor in the stress phase, B = 0.701, p = 0.048, Exp(B) = 2.106, 95%CI [1.00; 4.04]. The single officers (83.33% of the divorced and 55.56% of the single employees) and those of the staff that were more highly educated (78.72%) had elevated levels of burnout syndrome, and these manifested during the first 5 years of their service in the prison (77.78%). In Bulgaria at present the burnout syndrome has not been studied among employees working in correctional facilities. We found a high prevalence of the syndrome among the employees of the District Prison - Plovdiv. The younger, the single and the more educated employees had greater levels of burnout syndrome, which manifest during the first 5 years of their service. The results suggest that there is a need to develop and implement effective strategies to reduce and prevent

X-band EPR setup with THz light excitation of Novosibirsk Free Electron Laser: Goals, means, useful extras

NASA Astrophysics Data System (ADS)

Veber, Sergey L.; Tumanov, Sergey V.; Fursova, Elena Yu.; Shevchenko, Oleg A.; Getmanov, Yaroslav V.; Scheglov, Mikhail A.; Kubarev, Vitaly V.; Shevchenko, Daria A.; Gorbachev, Iaroslav I.; Salikova, Tatiana V.; Kulipanov, Gennady N.; Ovcharenko, Victor I.; Fedin, Matvey V.

2018-03-01

Electron Paramagnetic Resonance (EPR) station at the Novosibirsk Free Electron Laser (NovoFEL) user facility is described. It is based on X-band (∼9 GHz) EPR spectrometer and operates in both Continuous Wave (CW) and Time-Resolved (TR) modes, each allowing detection of either direct or indirect influence of high-power NovoFEL light (THz and mid-IR) on the spin system under study. The optics components including two parabolic mirrors, shutters, optical chopper and multimodal waveguide allow the light of NovoFEL to be directly fed into the EPR resonator. Characteristics of the NovoFEL radiation, the transmission and polarization-retaining properties of the waveguide used in EPR experiments are presented. The types of proposed experiments accessible using this setup are sketched. In most practical cases the high-power radiation applied to the sample induces its rapid temperature increase (T-jump), which is best visible in TR mode. Although such influence is a by-product of THz radiation, this thermal effect is controllable and can deliberately be used to induce and measure transient signals of arbitrary samples. The advantage of tunable THz radiation is the absence of photo-induced processes in the sample and its high penetration ability, allowing fast heating of a large portion of virtually any sample and inducing intense transients. Such T-jump TR EPR spectroscopy with THz pulses has been previewed for the two test samples, being a useful supplement for the main goals of the created setup.

Facile fabrication of ultrathin hybrid membrane for highly flexible supercapacitors via in-situ phase separation of polyethersulfone

NASA Astrophysics Data System (ADS)

Zhao, Xiaoning; Ran, Fen; Shen, Kuiwen; Yang, Yunlong; Wu, Jiayu; Niu, Xiaoqin; Kong, Lingbin; Kang, Long; Chen, Shaowei

2016-10-01

In this article, a facile method based on in-situ phase-separation was developed for the fabrication of ultrathin hybrid membranes for highly flexible supercapacitors. The structures and morphologies of the prepared electrodes were characterized by scanning electron microscopy (SEM), Fourier-transformed infrared spectroscopy (FTIR), and thermogravimetric analysis (TGA) measurements; and the electrochemical behaviors were examined in 2 M KOH solution. SEM and FTIR characterizations reveal that activated carbon was imbedded into the polymer membrane of polyethersulfone to form a uniform and flexible hybrid membrane. When the thin polymer-carbon membrane (PCM) was used as an electrode material for supercapacitor, a high specific capacitance of 169.4 Fg-1 was obtained at a current density of 0.5 Ag-1 along with good long-term cycle life of 94.6% capacity retention after 2000 charging-discharging cycles. Benefiting from these merits, the as-fabricated PCM//PCM cell shows an excellent electrochemical property. These results suggest a promising route towards the fabrication of highly flexible electrodes for high-performance supercapacitors.

Study of Plasma Energization during Magnetic Reconnection in the FLARE (Facility for Laboratory Reconnection Experiments)

NASA Astrophysics Data System (ADS)

Ji, H.; Bhattacharjee, A.; Prager, S.; Daughton, W.; Bale, S.; Carter, T.; Crocker, N.; Drake, J.; Egedal, J.; Sarff, J.; Wallace, J.; Chen, Y.; Cutler, R.; Fox, W.; Heitzenroeder, P.; Kalish, M.; Jara-Almonte, J.; Myers, C.; Ren, Y.; Yamada, M.; Yoo, J.

2015-11-01

Various regimes or ``phases'' are identified in a magnetic reconnection ``phase diagram'' which classifies different coupling mechanisms from the global system scales to the local dissipation scales. The FLARE device (http://flare.pppl.gov) is a new intermediate-scale plasma experiment under construction at Princeton to provide access to all of these phases directly relevant to space, solar, astrophysical, and fusion plasmas. Study of plasma energization during magnetic reconnection is one of major topics for the FLARE facility, which is planned to be a user facility. The motivating major physics questions regarding plasma energization and the planned collaborative research on these topics will be presented and discussed. Supported by NSF.

Radiation damage to macromolecules: kill or cure?

PubMed

Garman, Elspeth F; Weik, Martin

2015-03-01

Radiation damage induced by X-ray beams during macromolecular diffraction experiments remains an issue of concern in structural biology. While advances in our understanding of this phenomenon, driven in part by a series of workshops in this area, undoubtedly have been and are still being made, there are still questions to be answered. Eight papers in this volume give a flavour of ongoing investigations, addressing various issues. These range over: a proposed new metric derived from atomic B-factors for identifying potentially damaged amino acid residues, a study of the relative damage susceptibility of protein and DNA in a DNA/protein complex, a report of an indication of specific radiation damage to a protein determined from data collected using an X-ray free-electron laser (FEL), an account of the challenges in FEL raw diffraction data analysis, an exploration of the possibilities of using radiation damage induced phasing to solve structures using FELs, simulations of radiation damage as a function of FEL temporal pulse profiles, results on the influence of radiation damage during scanning X-ray diffraction measurements and, lastly, consideration of strategies for minimizing radiation damage during SAXS experiments. In this short introduction, these contributions are briefly placed in the context of other current work on radiation damage in the field.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Allaria, Enrico; Diviacco, Bruno; Callegari, Carlo

The two single-pass, externally seeded free-electron lasers (FELs) of the FERMI user facility are designed around Apple-II-type undulators that can operate at arbitrary polarization in the vacuum ultraviolet-to-soft x-ray spectral range. Furthermore, within each FEL tuning range, any output wavelength and polarization can be set in less than a minute of routine operations. We report the first demonstration of the full output polarization capabilities of FERMI FEL-1 in a campaign of experiments where the wavelength and nominal polarization are set to a series of representative values, and the polarization of the emitted intense pulses is thoroughly characterized by three independentmore » instruments and methods, expressly developed for the task. The measured radiation polarization is consistently >90% and is not significantly spoiled by the transport optics; differing, relative transport losses for horizontal and vertical polarization become more prominent at longer wavelengths and lead to a non-negligible ellipticity for an originally circularly polarized state. The results from the different polarimeter setups validate each other, allow a cross-calibration of the instruments, and constitute a benchmark for user experiments.« less

Control of the polarization of a vacuum-ultraviolet, high-gain, free-electron laser

DOE PAGES

Allaria, Enrico; Diviacco, Bruno; Callegari, Carlo; ...

2014-12-02

The two single-pass, externally seeded free-electron lasers (FELs) of the FERMI user facility are designed around Apple-II-type undulators that can operate at arbitrary polarization in the vacuum ultraviolet-to-soft x-ray spectral range. Furthermore, within each FEL tuning range, any output wavelength and polarization can be set in less than a minute of routine operations. We report the first demonstration of the full output polarization capabilities of FERMI FEL-1 in a campaign of experiments where the wavelength and nominal polarization are set to a series of representative values, and the polarization of the emitted intense pulses is thoroughly characterized by three independentmore » instruments and methods, expressly developed for the task. The measured radiation polarization is consistently >90% and is not significantly spoiled by the transport optics; differing, relative transport losses for horizontal and vertical polarization become more prominent at longer wavelengths and lead to a non-negligible ellipticity for an originally circularly polarized state. The results from the different polarimeter setups validate each other, allow a cross-calibration of the instruments, and constitute a benchmark for user experiments.« less

Parental and offspring associations of the metabolic syndrome in the Fels Longitudinal Study123

PubMed Central

Sabo, Roy T; Lu, Zheng; Deng, Xiaoyan; Ren, Chunfeng; Daniels, Stephen; Arslanian, Silva; Sun, Shumei S

2012-01-01

Background: Evidence shows that some causes of the metabolic syndrome (MS) begin in childhood, which could indicate a familial association, through either genetic inheritance or cohabitation. Objective: This study examined associations between parents and adult offspring diagnoses of the MS and its risk factors. Design: Measurements were obtained from adult participants and their adult offspring enrolled in the Fels Longitudinal Study, with simultaneous waist circumference, systolic blood pressure (SBP), diastolic blood pressure (DBP), triglycerides, HDL, and glucose observations used for diagnosis. On the basis of repeated measurements (in some cases), adult participants were classified as having the MS at least once or as never having the MS. Chi-square tests, ORs, and mixed-effects models were used to study familial associations. Results: Maternal (OR: 2.5; 95% CI: 1.1, 5.5) and paternal (OR: 4.1; 95% CI: 1.4, 12.1) MS classifications were significantly associated with MS classification in sons. MS classification in mothers and daughters (OR: 2.7; 95% CI: 0.9, 8.7; P = 0.08) was similar to that in sons but was not significant, whereas fathers and daughters were not associated (OR: 1.1; 95% CI: 0.4, 3.5). Maternal MS diagnoses were significantly and positively associated with triglycerides in male offspring and were significantly associated with SBP, DBP, and triglycerides in females. Paternal diagnoses were significantly associated only with DBP and HDL in male offspring. Conclusions: Parental MS diagnosis is significantly associated with MS diagnosis in adult male offspring, and adverse levels of certain risk factors are associated between offspring and parents, although these associations vary across risk factors and child sex. PMID:22811445

Three-dimensional, time-dependent simulation of free-electron lasers with planar, helical, and elliptical undulators

NASA Astrophysics Data System (ADS)

Freund, H. P.; van der Slot, P. J. M.; Grimminck, D. L. A. G.; Setija, I. D.; Falgari, P.

2017-02-01

Free-electron lasers (FELs) have been built ranging in wavelength from long-wavelength oscillators using partial wave guiding through ultraviolet through hard x-ray that are either seeded or start from noise. In addition, FELs that produce different polarizations of the output radiation ranging from linear through elliptic to circular polarization are currently under study. In this paper, we develop a three-dimensional, time-dependent formulation that is capable of modeling this large variety of FEL configurations including different polarizations. We employ a modal expansion for the optical field, i.e., a Gaussian expansion with variable polarization for free-space propagation. This formulation uses the full Newton-Lorentz force equations to track the particles through the optical and magnetostatic fields. As a result, arbitrary three-dimensional representations for different undulator configurations are implemented, including planar, helical, and elliptical undulators. In particular, we present an analytic model of an APPLE-II undulator to treat arbitrary elliptical polarizations, which is used to treat general elliptical polarizations. To model oscillator configurations, and allow propagation of the optical field outside the undulator and interact with optical elements, we link the FEL simulation with the optical propagation code OPC. We present simulations using the APPLE-II undulator model to produce elliptically polarized output radiation, and present a detailed comparison with recent experiments using a tapered undulator configuration at the Linac Coherent Light Source. Validation of the nonlinear formation is also shown by comparison with experimental results obtained in the Sorgente Pulsata Auto-amplificata di Radiazione Coerente SASE FEL experiment at ENEA Frascati, a seeded tapered amplifier experiment at Brookhaven National Laboratory, and the 10 kW upgrade oscillator experiment at the Thomas Jefferson National Accelerator Facility.

Sanford Underground Research Facility - The United State's Deep Underground Research Facility

NASA Astrophysics Data System (ADS)

Vardiman, D.

2012-12-01

The 2.5 km deep Sanford Underground Research Facility (SURF) is managed by the South Dakota Science and Technology Authority (SDSTA) at the former Homestake Mine site in Lead, South Dakota. The US Department of Energy currently supports the development of the facility using a phased approach for underground deployment of experiments as they obtain an advanced design stage. The geology of the Sanford Laboratory site has been studied during the 125 years of operations at the Homestake Mine and more recently as part of the preliminary geotechnical site investigations for the NSF's Deep Underground Science and Engineering Laboratory project. The overall geology at DUSEL is a well-defined stratigraphic sequence of schist and phyllites. The three major Proterozoic units encountered in the underground consist of interbedded schist, metasediments, and amphibolite schist which are crosscut by Tertiary rhyolite dikes. Preliminary geotechnical site investigations included drift mapping, borehole drilling, borehole televiewing, in-situ stress analysis, laboratory analysis of core, mapping and laser scanning of new excavations, modeling and analysis of all geotechnical information. The investigation was focused upon the determination if the proposed site rock mass could support the world's largest (66 meter diameter) deep underground excavation. While the DUSEL project has subsequently been significantly modified, these data are still available to provide a baseline of the ground conditions which may be judiciously extrapolated throughout the entire Proterozoic rock assemblage for future excavations. Recommendations for facility instrumentation and monitoring were included in the preliminary design of the DUSEL project design and include; single and multiple point extensometers, tape extensometers and convergence measurements (pins), load cells and pressure cells, smart cables, inclinometers/Tiltmeters, Piezometers, thermistors, seismographs and accelerometers, scanners (laser

ESO adaptive optics facility progress report

NASA Astrophysics Data System (ADS)

Arsenault, Robin; Madec, Pierre-Yves; Paufique, Jerome; La Penna, Paolo; Stroebele, Stefan; Vernet, Elise; Pirard, Jean-Francois; Hackenberg, Wolfgang; Kuntschner, Harald; Jochum, Lieselotte; Kolb, Johann; Muller, Nicolas; Le Louarn, Miska; Amico, Paola; Hubin, Norbert; Lizon, Jean-Louis; Ridings, Rob; Abad, Jose A.; Fischer, Gert; Heinz, Volker; Kiekebusch, Mario; Argomedo, Javier; Conzelmann, Ralf; Tordo, Sebastien; Donaldson, Robert; Soenke, Christian; Duhoux, Philippe; Fedrigo, Enrico; Delabre, Bernard; Jost, Andreas; Duchateau, Michel; Downing, Mark; Moreno, Javier R.; Dorn, Reinhold; Manescau, Antonio; Bonaccini Calia, Domenico; Quattri, Marco; Dupuy, Christophe; Guidolin, Ivan M.; Comin, Mauro; Guzman, Ronald; Buzzoni, Bernard; Quentin, Jutta; Lewis, Steffan; Jolley, Paul; Kraus, Maximilian; Pfrommer, Thomas; Biasi, Roberto; Gallieni, Daniele; Bechet, Clementine; Stuik, Remko

2012-07-01

The ESO Adaptive Optics Facility (AOF) consists in an evolution of one of the ESO VLT unit telescopes to a laser driven adaptive telescope with a deformable mirror in its optical train. The project has completed the procurement phase and several large structures have been delivered to Garching (Germany) and are being integrated (the AO modules GRAAL and GALACSI and the ASSIST test bench). The 4LGSF Laser (TOPTICA) has undergone final design review and a pre-production unit has been built and successfully tested. The Deformable Secondary Mirror is fully integrated and system tests have started with the first science grade thin shell mirror delivered by SAGEM. The integrated modules will be tested in stand-alone mode in 2012 and upon delivery of the DSM in late 2012, the system test phase will start. A commissioning strategy has been developed and will be updated before delivery to Paranal. A substantial effort has been spent in 2011-2012 to prepare the unit telescope to receive the AOF by preparing the mechanical interfaces and upgrading the cooling and electrical network. This preparation will also simplify the final installation of the facility on the telescope. A lot of attention is given to the system calibration, how to record and correct any misalignment and control the whole facility. A plan is being developed to efficiently operate the AOF after commissioning. This includes monitoring a relevant set of atmospheric parameters for scheduling and a Laser Traffic control system to assist the operator during the night and help/support the observing block preparation.

A guideline for interpersonal capabilities enhancement to support sustainable facility management practice

NASA Astrophysics Data System (ADS)

Sarpin, Norliana; Kasim, Narimah; Zainal, Rozlin; Noh, Hamidun Mohd

2018-04-01

Facility management is the key phase in the development cycle of an assets and spans over a considerable length of time. Therefore, facility managers are in a commanding position to maximise the potential of sustainability through the development phases from construction, operation, maintenance and upgrade leading to decommission and deconstruction. Sustainability endeavours in facility management practices will contribute to reducing energy consumption, waste and running costs. Furthermore, it can also help in improving organisational productivity, financial return and community standing of the organisation. Facility manager should be empowered with the necessary knowledge and capabilities at the forefront facing sustainability challenge. However, literature studies show a gap between the level of awareness, specific knowledge and the necessary skills required to pursue sustainability in the facility management professional. People capability is considered as the key enabler in managing the sustainability agenda as well as being central to the improvement of competency and innovation in an organisation. This paper aims to develop a guidelines for interpersonal capabilities to support sustainability in facility management practice. Starting with a total of 7 critical interpersonal capabilities factors identified from previous questionnaire survey, the authors conducted an interview with 3 experts in facility management to assess the perceived importance of these factors. The findings reveal a set of guidelines for the enhancement of interpersonal capabilities among facility managers by providing what can be done to acquire these factors and how it can support the application of sustainability in their practice. The findings of this paper are expected to form the basis of a mechanism framework developed to equip facility managers with the right knowledge, to continue education and training and to develop new mind-sets to enhance the implementation of sustainability

Evaluation of mercury in the liquid waste processing facilities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jain, Vijay; Shah, Hasmukh; Occhipinti, John E.

2015-08-13

This report provides a summary of Phase I activities conducted to support an Integrated Evaluation of Mercury in Liquid Waste System (LWS) Processing Facilities. Phase I activities included a review and assessment of the liquid waste inventory and chemical processing behavior of mercury using a system by system review methodology approach. Gaps in understanding mercury behavior as well as action items from the structured reviews are being tracked. 64% of the gaps and actions have been resolved.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cornacchia, Massimo

The VISA (Visible to Infrared SASE Amplifier) SASE free electron laser has been successfully operated at the Accelerator Test Facility (ATF) at BNL. High gain and saturation were observed at 840 nm. We describe here the diagnostic system, experimental procedures and data reduction algorithms, as the FEL performance was measured along the length of the undulator. We also discuss selected spectral radiation measurements.

Development of laboratory testing facility for evaluation of base-soil behavior under repeated loading : phase-1 : feasibility study.

DOT National Transportation Integrated Search

2008-03-01

The main objective of this study was to determine the most beneficial and cost-effective accelerated load facility that can be used in conjunction with LTRCs Accelerated Load Facility (ALF). The facility will be used primarily for conducting preli...

Gas-grain simulation facility: Aerosol and particle research in microgravity

NASA Technical Reports Server (NTRS)

Huntington, Judith L. (Editor); Greenwald, Ken (Editor); Rogers, C. Fred (Editor); Stratton, David M. (Editor); Simmons, Brenda (Editor); Fonda, Mark L. (Editor)

1994-01-01

This document reports on the proceedings of the Gas-Grain Simulation Facility (GGSF) Science Workshop which was co-hosted by NASA Ames Research Center and Desert Research Institute, University of Nevada System, and held in Las Vegas, Nevada, on May 4-6, 1992. The intent of the workshop was to bring together the science community of potential GGSF experimenters, Science Working Group and staff members, and the Phase A contractor to review the Phase A design with the science participants and to facilitate communication between the science community and the hardware developers. The purpose of this report is to document the information disseminated at the workshop, to record the participants' review of the Phase A GGSF design concept and the current science and technical requirements for the Facility, and to respond to any questions or concerns that were raised at the Workshop. Recommendations for the future based on numerous discussions with the participants are documented, as well as science presentations and poster sessions that were given at the Workshop and a summary of 21 candidate experiments.

Developing Mobile BIM/2D Barcode-Based Automated Facility Management System

PubMed Central

Chen, Yen-Pei

2014-01-01

Facility management (FM) has become an important topic in research on the operation and maintenance phase. Managing the work of FM effectively is extremely difficult owing to the variety of environments. One of the difficulties is the performance of two-dimensional (2D) graphics when depicting facilities. Building information modeling (BIM) uses precise geometry and relevant data to support the facilities depicted in three-dimensional (3D) object-oriented computer-aided design (CAD). This paper proposes a new and practical methodology with application to FM that uses an integrated 2D barcode and the BIM approach. Using 2D barcode and BIM technologies, this study proposes a mobile automated BIM-based facility management (BIMFM) system for FM staff in the operation and maintenance phase. The mobile automated BIMFM system is then applied in a selected case study of a commercial building project in Taiwan to verify the proposed methodology and demonstrate its effectiveness in FM practice. The combined results demonstrate that a BIMFM-like system can be an effective mobile automated FM tool. The advantage of the mobile automated BIMFM system lies not only in improving FM work efficiency for the FM staff but also in facilitating FM updates and transfers in the BIM environment. PMID:25250373

Developing mobile BIM/2D barcode-based automated facility management system.

PubMed

Lin, Yu-Cheng; Su, Yu-Chih; Chen, Yen-Pei

2014-01-01

Facility management (FM) has become an important topic in research on the operation and maintenance phase. Managing the work of FM effectively is extremely difficult owing to the variety of environments. One of the difficulties is the performance of two-dimensional (2D) graphics when depicting facilities. Building information modeling (BIM) uses precise geometry and relevant data to support the facilities depicted in three-dimensional (3D) object-oriented computer-aided design (CAD). This paper proposes a new and practical methodology with application to FM that uses an integrated 2D barcode and the BIM approach. Using 2D barcode and BIM technologies, this study proposes a mobile automated BIM-based facility management (BIMFM) system for FM staff in the operation and maintenance phase. The mobile automated BIMFM system is then applied in a selected case study of a commercial building project in Taiwan to verify the proposed methodology and demonstrate its effectiveness in FM practice. The combined results demonstrate that a BIMFM-like system can be an effective mobile automated FM tool. The advantage of the mobile automated BIMFM system lies not only in improving FM work efficiency for the FM staff but also in facilitating FM updates and transfers in the BIM environment.

SuperCDMS Underground Detector Fabrication Facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Platt, M.; Mahapatra, R.; Bunker, Raymond A.

The SuperCDMS SNOLAB dark matter experiment processes Ge and Si crystals into fully tested phonon and ionization detectors at surface fabrication and test facilities. If not mitigated, it is anticipated that trace-level production of radioisotopes in the crystals due to exposure to cosmic rays at (or above) sea level will result in the dominant source of background events in future dark matter searches using the current SuperCDMS detector technology. Fabrication and testing of detectors in underground facilities shielded from cosmic radiation is one way to directly reduce production of trace levels of radioisotopes, thereby improving experimental sensitivity for the discoverymore » of dark matter beyond the level of the current experiment. In this report, we investigate the cost and feasibility to establish a complete detector fabrication processing chain in an underground location to mitigate cosmogenic activation of the Ge and Si detector substrates. For a specific and concrete evaluation, we explore options for such a facility located at SNOLAB, an underground laboratory in Sudbury, Canada hosting the current and future experimental phases of SuperCDMS.« less

The design of the optical Thomson scattering diagnostic for the National Ignition Facility [The preliminary design of the optical Thomson scattering diagnostic for the National Ignition Facility

DOE PAGES

Datte, P. S.; Ross, J. S.; Froula, D. H.; ...

2016-09-21

Here, the National Ignition Facility (NIF) is a 192 laser beam facility designed to support the Stockpile Stewardship, High Energy Density and Inertial Confinement Fusion (ICF) programs. We report on the design of an Optical Thomson Scattering (OTS) diagnostic that has the potential to transform the community’s understanding of NIF hohlraum physics by providing first principle, local, time-resolved measurements of under-dense plasma conditions. The system design allows operation with different probe laser wavelengths by manual selection of the appropriate beam splitter and gratings before the shot. A deep-UV probe beam (λ 0-210 nm) will be used to optimize the scatteredmore » signal for plasma densities of 5 × 10 20 electrons/cm 3 while a 3ω probe will be used for experiments investigating lower density plasmas of 1 × 10 19 electrons/cm 3. We report the phase I design of a two phase design strategy. Phase I includes the OTS telescope, spectrometer, and streak camera; these will be used to assess the background levels at NIF. Phase II will include the design and installation of a probe laser.« less

The design of the optical Thomson scattering diagnostic for the National Ignition Facility [The preliminary design of the optical Thomson scattering diagnostic for the National Ignition Facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Datte, P. S.; Ross, J. S.; Froula, D. H.

Here, the National Ignition Facility (NIF) is a 192 laser beam facility designed to support the Stockpile Stewardship, High Energy Density and Inertial Confinement Fusion (ICF) programs. We report on the design of an Optical Thomson Scattering (OTS) diagnostic that has the potential to transform the community’s understanding of NIF hohlraum physics by providing first principle, local, time-resolved measurements of under-dense plasma conditions. The system design allows operation with different probe laser wavelengths by manual selection of the appropriate beam splitter and gratings before the shot. A deep-UV probe beam (λ 0-210 nm) will be used to optimize the scatteredmore » signal for plasma densities of 5 × 10 20 electrons/cm 3 while a 3ω probe will be used for experiments investigating lower density plasmas of 1 × 10 19 electrons/cm 3. We report the phase I design of a two phase design strategy. Phase I includes the OTS telescope, spectrometer, and streak camera; these will be used to assess the background levels at NIF. Phase II will include the design and installation of a probe laser.« less

Indian Test Facility (INTF) and its updates

NASA Astrophysics Data System (ADS)

Bandyopadhyay, M.; Chakraborty, A.; Rotti, C.; Joshi, J.; Patel, H.; Yadav, A.; Shah, S.; Tyagi, H.; Parmar, D.; Sudhir, Dass; Gahlaut, A.; Bansal, G.; Soni, J.; Pandya, K.; Pandey, R.; Yadav, R.; Nagaraju, M. V.; Mahesh, V.; Pillai, S.; Sharma, D.; Singh, D.; Bhuyan, M.; Mistry, H.; Parmar, K.; Patel, M.; Patel, K.; Prajapati, B.; Shishangiya, H.; Vishnudev, M.; Bhagora, J.

2017-04-01

To characterize ITER Diagnostic Neutral Beam (DNB) system with full specification and to support IPR’s negative ion beam based neutral beam injector (NBI) system development program, a R&D facility, named INTF is under commissioning phase. Implementation of a successful DNB at ITER requires several challenges need to be overcome. These issues are related to the negative ion production, its neutralization and corresponding neutral beam transport over the path lengths of ∼ 20.67 m to reach ITER plasma. DNB is a procurement package for INDIA, as an in-kind contribution to ITER. Since ITER is considered as a nuclear facility, minimum diagnostic systems, linked with safe operation of the machine are planned to be incorporated in it and so there is difficulty to characterize DNB after onsite commissioning. Therefore, the delivery of DNB to ITER will be benefited if DNB is operated and characterized prior to onsite commissioning. INTF has been envisaged to be operational with the large size ion source activities in the similar timeline, as with the SPIDER (RFX, Padova) facility. This paper describes some of the development updates of the facility.

Materials Science Clean Room Facility at Tulane University (Final Technical Report)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Altiero, Nicholas

2010-09-30

The project involves conversion of a 3,000 sq. ft. area into a clean room facility for materials science research. It will be accomplished in phases. Phase I will involve preparation of the existing space, acquisition and installation of clean room equipped with a pulsed laser deposition (PLD) processing system, and conversion of ancillary space to facilitate the interface with the clean room. From a capital perspective, Phases II and III will involve the acquisition of additional processing, fabrication, and characterization equipment and capabilities.

Present status of the liquid lithium target facility in the international fusion materials irradiation facility (IFMIF)

NASA Astrophysics Data System (ADS)

Nakamura, Hiroo; Riccardi, B.; Loginov, N.; Ara, K.; Burgazzi, L.; Cevolani, S.; Dell'Orco, G.; Fazio, C.; Giusti, D.; Horiike, H.; Ida, M.; Ise, H.; Kakui, H.; Matsui, H.; Micciche, G.; Muroga, T.; Nakamura, Hideo; Shimizu, K.; Sugimoto, M.; Suzuki, A.; Takeuchi, H.; Tanaka, S.; Yoneoka, T.

2004-08-01

During the three year key element technology phase of the International Fusion Materials Irradiation Facility (IFMIF) project, completed at the end of 2002, key technologies have been validated. In this paper, these results are summarized. A water jet experiment simulating Li flow validated stable flow up to 20 m/s with a double reducer nozzle. In addition, a small Li loop experiment validated stable Li flow up to 14 m/s. To control the nitrogen content in Li below 10 wppm will require surface area of a V-Ti alloy getter of 135 m 2. Conceptual designs of diagnostics have been carried out. Moreover, the concept of a remote handling system to replace the back wall based on `cut and reweld' and `bayonet' options has been established. Analysis by FMEA showed safe operation of the target system. Recent activities in the transition phase, started in 2003, and plan for the next phase are also described.

Extended Statistical Short-Range Guidance for Peak Wind Speed Analyses at the Shuttle Landing Facility: Phase II Results

NASA Technical Reports Server (NTRS)

Lambert, Winifred C.

2003-01-01

This report describes the results from Phase II of the AMU's Short-Range Statistical Forecasting task for peak winds at the Shuttle Landing Facility (SLF). The peak wind speeds are an important forecast element for the Space Shuttle and Expendable Launch Vehicle programs. The 45th Weather Squadron and the Spaceflight Meteorology Group indicate that peak winds are challenging to forecast. The Applied Meteorology Unit was tasked to develop tools that aid in short-range forecasts of peak winds at tower sites of operational interest. A seven year record of wind tower data was used in the analysis. Hourly and directional climatologies by tower and month were developed to determine the seasonal behavior of the average and peak winds. Probability density functions (PDF) of peak wind speed were calculated to determine the distribution of peak speed with average speed. These provide forecasters with a means of determining the probability of meeting or exceeding a certain peak wind given an observed or forecast average speed. A PC-based Graphical User Interface (GUI) tool was created to display the data quickly.

Downgrading Nuclear Facilities to Radiological Facilities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jarry, Jeffrey F.; Farr, Jesse Oscar; Duran, Leroy

2015-08-01

Based on inventory reductions and the use of alternate storage facilities, the Sandia National Laboratories (SNL) downgraded 4 SNL Hazard Category 3 (HC-3) nuclear facilities to less-than-HC-3 radiological facilities. SNL’s Waste Management and Pollution Prevention Department (WMPPD) managed the HC-3 nuclear facilities and implemented the downgrade. This paper will examine the downgrade process,

Lunar landing and launch facilities and operations

NASA Technical Reports Server (NTRS)

1988-01-01

A preliminary design of a lunar landing and launch facility for a Phase 3 lunar base is formulated. A single multipurpose vehicle for the lunar module is assumed. Three traffic levels are envisioned: 6, 12, and 24 landings/launches per year. The facility is broken down into nine major design items. A conceptual description of each of these items is included. Preliminary sizes, capacities, and/or other relevant design data for some of these items are obtained. A quonset hut tent-like structure constructed of aluminum rods and aluminized mylar panels is proposed. This structure is used to provide a constant thermal environment for the lunar modules. A structural design and thermal analysis is presented. Two independent designs for a bridge crane to unload/load heavy cargo from the lunar module are included. Preliminary investigations into cryogenic propellant storage and handling, landing/launch guidance and control, and lunar module maintenance requirements are performed. Also, an initial study into advanced concepts for application to Phase 4 or 5 lunar bases has been completed in a report on capturing, condensing, and recycling the exhaust plume from a lunar launch.

X-band EPR setup with THz light excitation of Novosibirsk Free Electron Laser: Goals, means, useful extras.

PubMed

Veber, Sergey L; Tumanov, Sergey V; Fursova, Elena Yu; Shevchenko, Oleg A; Getmanov, Yaroslav V; Scheglov, Mikhail A; Kubarev, Vitaly V; Shevchenko, Daria A; Gorbachev, Iaroslav I; Salikova, Tatiana V; Kulipanov, Gennady N; Ovcharenko, Victor I; Fedin, Matvey V

2018-03-01

Electron Paramagnetic Resonance (EPR) station at the Novosibirsk Free Electron Laser (NovoFEL) user facility is described. It is based on X-band (∼9 GHz) EPR spectrometer and operates in both Continuous Wave (CW) and Time-Resolved (TR) modes, each allowing detection of either direct or indirect influence of high-power NovoFEL light (THz and mid-IR) on the spin system under study. The optics components including two parabolic mirrors, shutters, optical chopper and multimodal waveguide allow the light of NovoFEL to be directly fed into the EPR resonator. Characteristics of the NovoFEL radiation, the transmission and polarization-retaining properties of the waveguide used in EPR experiments are presented. The types of proposed experiments accessible using this setup are sketched. In most practical cases the high-power radiation applied to the sample induces its rapid temperature increase (T-jump), which is best visible in TR mode. Although such influence is a by-product of THz radiation, this thermal effect is controllable and can deliberately be used to induce and measure transient signals of arbitrary samples. The advantage of tunable THz radiation is the absence of photo-induced processes in the sample and its high penetration ability, allowing fast heating of a large portion of virtually any sample and inducing intense transients. Such T-jump TR EPR spectroscopy with THz pulses has been previewed for the two test samples, being a useful supplement for the main goals of the created setup. Copyright © 2018 Elsevier Inc. All rights reserved.

Component-resolved microarray analysis of IgE sensitization profiles to Felis catus major allergen molecules in Russian cat-allergic patients.

PubMed

Dolgova, Anna Sergeevna; Sudina, Anna Evgenevna; Cherkashina, Anna Sergeevna; Stukolova, Olga Alekseevna

We aimed to determine the profile of IgE reactivity to three major cat allergens, Fel d 1, Fel d 2 and Fel d 4, in cat-allergic patients in the Moscow region in Russia. sIgE levels to recombinant proteins expressed in Escherichia coli (Fel d 1 and Fel d 4) and to Fel d 2 protein purified from cat serum were measured using a microarray method developed in our laboratory. Sera from 174 anonymous subjects with a positive reaction (≥0.35 IU/mL) to cat dander extract (e1, ImmunoCAP) and 56 negative controls were used for IgE testing. Fel d 1 was recognized by 92.5%, Fel d 2 by 29.9% and Fel d 4 by 39.1% of the tested patient sera. The sensitivity to these three proteins was approximately 98% compared to cat dander extract (correlation coefficient to ImmunoCAP is 0.94 with PPV = 0.99 and NPV = 0.95). These predictive values appeared to be even more statistically significant than the divergence between the ISAC IgE test and the extract-based singleplex ImmunoCAP. The combination of the three investigated proteins (Fel d 1, Fel d 2 and Fel d 4) is suitable for in vitro molecular (serological) diagnosis of cat allergy in this region as a complement to cat dander extract. Moreover, with this method, we found distinction between Fel d 2 and other Feline sIgEs formation.

Axial interaction free-electron laser

DOEpatents

Carlsten, Bruce E.

1997-01-01

Electron orbits from a helical axial wiggler in an axial guide field are absolutely unstable as power is extracted from the particles. For off-axis beams an axial FEL mechanism exists when the axial electric field in a TM mode is wiggled to interact with the axial velocity of the electrons that form the beam. The interaction strength is comparable to that for helical FELs and is insensitive to beam orbit errors. The orbits for this mechanism are extremely stable in the absence of space charge and lead to high extraction efficiencies without particle phasing incoherence or interception. This interaction mechanism is suitable for use with intense annular electron beams for high power generation at microwave frequencies.

Axial interaction free-electron laser

DOEpatents

Carlsten, B.E.

1997-09-02

Electron orbits from a helical axial wiggler in an axial guide field are absolutely unstable as power is extracted from the particles. For off-axis beams an axial FEL mechanism exists when the axial electric field in a TM mode is wiggled to interact with the axial velocity of the electrons that form the beam. The interaction strength is comparable to that for helical FELs and is insensitive to beam orbit errors. The orbits for this mechanism are extremely stable in the absence of space charge and lead to high extraction efficiencies without particle phasing incoherence or interception. This interaction mechanism is suitable for use with intense annular electron beams for high power generation at microwave frequencies. 5 figs.

Building Information Modeling (BIM) Primer. Report 1: Facility Life-Cycle Process and Technology Innovation

DTIC Science & Technology

2012-08-01

Building Information Modeling ( BIM ) Primer Report 1: Facility Life-cycle Process and Technology Innovation In fo...is unlimited. ERDC/ITL TR-12-2 August 2012 Building Information Modeling ( BIM ) Primer Report 1: Facility Life-cycle Process and Technology...and to enhance the quality of projects through the design, construction, and handover phases. Building Information Modeling ( BIM ) is a

The design of the optical Thomson scattering diagnostic for the National Ignition Facility.

PubMed

Datte, P S; Ross, J S; Froula, D H; Daub, K D; Galbraith, J; Glenzer, S; Hatch, B; Katz, J; Kilkenny, J; Landen, O; Manha, D; Manuel, A M; Molander, W; Montgomery, D; Moody, J; Swadling, G F; Weaver, J

2016-11-01

The National Ignition Facility (NIF) is a 192 laser beam facility designed to support the Stockpile Stewardship, High Energy Density and Inertial Confinement Fusion (ICF) programs. We report on the design of an Optical Thomson Scattering (OTS) diagnostic that has the potential to transform the community's understanding of NIF hohlraum physics by providing first principle, local, time-resolved measurements of under-dense plasma conditions. The system design allows operation with different probe laser wavelengths by manual selection of the appropriate beam splitter and gratings before the shot. A deep-UV probe beam (λ 0 -210 nm) will be used to optimize the scattered signal for plasma densities of 5 × 10 20 electrons/cm 3 while a 3ω probe will be used for experiments investigating lower density plasmas of 1 × 10 19 electrons/cm 3 . We report the phase I design of a two phase design strategy. Phase I includes the OTS telescope, spectrometer, and streak camera; these will be used to assess the background levels at NIF. Phase II will include the design and installation of a probe laser.

Coutts/Sweetgrass automated border crossing : phase I

DOT National Transportation Integrated Search

1999-03-01

The Coutts/Sweetgrass Automated Border Crossing Project was intended to improve operational efficiency of this rural border crossing facility using ITS applications. Phase I of the Coutts/Sweetgrass Automated Border Crossing Project was intended to r...

A facile and efficient single-step approach for the fabrication of vancomycin functionalized polymer-based monolith as chiral stationary phase for nano-liquid chromatography.

PubMed

Xu, Dongsheng; Shao, Huikai; Luo, Rongying; Wang, Qiqin; Sánchez-López, Elena; Fanali, Salvatore; Marina, Maria Luisa; Jiang, Zhengjin

2018-07-06

A facile single-step preparation strategy for fabricating vancomycin functionalized organic polymer-based monolith within 100μm fused-silica capillary was developed. The synthetic chiral functional monomer, i.e 2-isocyanatoethyl methacrylate (ICNEML) derivative of vancomycin, was co-polymerized with the cross-linker ethylene dimethacrylate (EDMA) in the presence of methanol and dimethyl sulfoxide as the selected porogens. The co-polymerization conditions were systematically optimized in order to obtain satisfactory column performance. Adequate permeability, stability and column morphology were observed for the optimized poly(ICNEML-vancomycin-co-EDMA) monolith. A series of chiral drugs were evaluated on the monolith in either polar organic-phase or reversed-phase modes. After the optimization of separation conditions, baseline or partial enantioseparation were obtained for series of drugs including thalidomide, colchicine, carteolol, salbutamol, clenbuterol and several other β-blockers. The proposed single-step approach not only resulted in a vancomycin functionalized organic polymer-based monolith with acceptable performance, but also significantly simplified the preparation procedure by reducing time and labor. Copyright © 2018 Elsevier B.V. All rights reserved.

Integrated Disposal Facility FY2010 Glass Testing Summary Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pierce, Eric M.; Bacon, Diana H.; Kerisit, Sebastien N.

2010-09-30

Pacific Northwest National Laboratory was contracted by Washington River Protection Solutions, LLC to provide the technical basis for estimating radionuclide release from the engineered portion of the disposal facility (e.g., source term). Vitrifying the low-activity waste at Hanford is expected to generate over 1.6 × 105 m3 of glass (Puigh 1999). The volume of immobilized low-activity waste (ILAW) at Hanford is the largest in the DOE complex and is one of the largest inventories (approximately 0.89 × 1018 Bq total activity) of long-lived radionuclides, principally 99Tc (t1/2 = 2.1 × 105), planned for disposal in a low-level waste (LLW) facility.more » Before the ILAW can be disposed, DOE must conduct a performance assessement (PA) for the Integrated Disposal Facility (IDF) that describes the long-term impacts of the disposal facility on public health and environmental resources. As part of the ILAW glass testing program PNNL is implementing a strategy, consisting of experimentation and modeling, in order to provide the technical basis for estimating radionuclide release from the glass waste form in support of future IDF PAs. The purpose of this report is to summarize the progress made in fiscal year (FY) 2010 toward implementing the strategy with the goal of developing an understanding of the long-term corrosion behavior of low-activity waste glasses. The emphasis in FY2010 was the completing an evaluation of the most sensitive kinetic rate law parameters used to predict glass weathering, documented in Bacon and Pierce (2010), and transitioning from the use of the Subsurface Transport Over Reactive Multi-phases to Subsurface Transport Over Multiple Phases computer code for near-field calculations. The FY2010 activities also consisted of developing a Monte Carlo and Geochemical Modeling framework that links glass composition to alteration phase formation by 1) determining the structure of unreacted and reacted glasses for use as input information into Monte

The Fluids and Combustion Facility

NASA Technical Reports Server (NTRS)

Kundu, Sampa

2004-01-01

Microgravity is an environment with very weak gravitational effects. The Fluids and Combustion Facility (FCF) on the International Space Station (ISS) will support the study of fluid physics and combustion science in a long-duration microgravity environment. The Fluid Combustion Facility's design will permit both independent and remote control operations from the Telescience Support Center. The crew of the International Space Station will continue to insert and remove the experiment module, store and reload removable data storage and media data tapes, and reconfigure diagnostics on either side of the optics benches. Upon completion of the Fluids Combustion Facility, about ten experiments will be conducted within a ten-year period. Several different areas of fluid physics will be studied in the Fluids Combustion Facility. These areas include complex fluids, interfacial phenomena, dynamics and instabilities, and multiphase flows and phase change. Recently, emphasis has been placed in areas that relate directly to NASA missions including life support, power, propulsion, and thermal control systems. By 2006 or 2007, a Fluids Integrated Rack (FIR) and a Combustion Integrated Rack (CIR) will be installed inside the International Space Station. The Fluids Integrated Rack will contain all the hardware and software necessary to perform experiments in fluid physics. A wide range of experiments that meet the requirements of the international space station, including research from other specialties, will be considered. Experiments will be contained in subsystems such as the international standard payload rack, the active rack isolation system, the optics bench, environmental subsystem, electrical power control unit, the gas interface subsystem, and the command and data management subsystem. In conclusion, the Fluids and Combustion Facility will allow researchers to study fluid physics and combustion science in a long-duration microgravity environment. Additional information is

The challenge of logistics facilities development

NASA Technical Reports Server (NTRS)

Davis, James R.

1987-01-01

The paper discusses the experiences of a group of engineers and logisticians at John F. Kennedy Space center in the design, construction and activation of a consolidated logistics facility for support of Space Transportation System ground operations and maintenance. The planning, methodology and processes are covered, with emphasis placed on unique aspects and lessons learned. The project utilized a progressive design, baseline and build concept for each phase of construction, with the Government exercising funding and configuration oversight.

Safety analysis in test facility design

NASA Astrophysics Data System (ADS)

Valk, A.; Jonker, R. J.

1990-09-01

The application of safety analysis techniques as developed in, for example nuclear and petrochemical industry, can be very beneficial in coping with the increasing complexity of modern test facility installations and their operations. To illustrate the various techniques available and their phasing in a project, an overview of the most commonly used techniques is presented. Two case studies are described: the hazard and operability study techniques and safety zoning in relation to the possible presence of asphyxiating atmospheres.

Langley Aerothermodynamic Facilities Complex: Enhancements and Testing Capabilities

NASA Technical Reports Server (NTRS)

Micol, J. R.

1998-01-01

Description, capabilities, recent upgrades, and utilization of the NASA Langley Research Center (LaRC) Aerothermodynamic Facilities Complex (AFC) are presented. The AFC consists of five hypersonic, blow-down-to-vacuum wind tunnels that collectively provide a range of Mach number from 6 to 20, unit Reynolds number from 0.04 to 22 million per foot and, most importantly for blunt configurations, normal shock density ratio from 4 to 12. These wide ranges of hypersonic simulation parameters are due, in part, to the use of three different test gases (air, helium, and tetrafluoromethane), thereby making several of the facilities unique. The Complex represents nearly three-fourths of the conventional (as opposed to impulse)-type hypersonic wind tunnels operational in this country. AFC facilities are used to assess and optimize the hypersonic aerodynamic performance and aeroheating characteristics of aerospace vehicle concepts and to provide benchmark aerodynamic/aeroheating data fr generating the flight aerodynamic databook and final design of the thermal protection system (TPS) (e.g., establishment of flight limitations not to exceed TPS design limits). Modifications and enhancements of AFC hardware components and instrumentation have been pursued to increase capability, reliability, and productivity in support of programmatic goals. Examples illustrating facility utilization in recent years to generate essentially all of the experimental hypersonic aerodynamic and aeroheating information for high-priority, fast-paced Agency programs are presented. These programs include Phase I of the Reusable Launch Vehicle (RLV) Advanced Technology Demonstrator, X-33 program, PHase II of the X-33 program, X-34 program, the Hyper-X program ( a Mach 5,7, and 10 airbreathing propulsion flight experiment), and the X-38 program (Experimental Crew Return Vehicle, X-CRV). Current upgrades/enchancements and future plans for the AFC are discussed.

Proliferation resistance assessments during the design phase of a recycling facility as a means of reducing proliferation risks

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lindell, M.A.; Grape, S.; Haekansson, A.

The sustainability criterion for Gen IV nuclear energy systems inherently presumes the availability of efficient fuel recycling capabilities. One area for research on advanced fuel recycling concerns safeguards aspects of this type of facilities. Since a recycling facility may be considered as sensitive from a non-proliferation perspective, it is important to address these issues early in the design process, according to the principle of Safeguards By Design. Presented in this paper is a mode of procedure, where assessments of the proliferation resistance (PR) of a recycling facility for fast reactor fuel have been performed so as to identify the weakestmore » barriers to proliferation of nuclear material. Two supplementing established methodologies have been applied; TOPS (Technological Opportunities to increase Proliferation resistance of nuclear power Systems) and PR-PP (Proliferation Resistance and Physical Protection evaluation methodology). The chosen fuel recycling facility belongs to a small Gen IV lead-cooled fast reactor system that is under study in Sweden. A schematic design of the recycling facility, where actinides are separated using solvent extraction, has been examined. The PR assessment methodologies make it possible to pinpoint areas in which the facility can be improved in order to reduce the risk of diversion. The initial facility design may then be slightly modified and/or safeguards measures may be introduced to reduce the total identified proliferation risk. After each modification of design and/or safeguards implementation, a new PR assessment of the revised system can then be carried out. This way, each modification can be evaluated and new ways to further enhance the proliferation resistance can be identified. This type of iterative procedure may support Safeguards By Design in the planning of new recycling plants and other nuclear facilities. (authors)« less

Electromagnetic Fields Associated with Commercial Solar Photovoltaic Electric Power Generating Facilities.

PubMed

Tell, R A; Hooper, H C; Sias, G G; Mezei, G; Hung, P; Kavet, R

2015-01-01

The southwest region of the United States is expected to experience an expansion of commercial solar photovoltaic generation facilities over the next 25 years. A solar facility converts direct current generated by the solar panels to three-phase 60-Hz power that is fed to the grid. This conversion involves sequential processing of the direct current through an inverter that produces low-voltage three-phase power, which is stepped up to distribution voltage (∼12 kV) through a transformer. This study characterized magnetic and electric fields between the frequencies of 0 Hz and 3 GHz at two facilities operated by the Southern California Edison Company in Porterville, CA and San Bernardino, CA. Static magnetic fields were very small compared to exposure limits established by IEEE and ICNIRP. The highest 60-Hz magnetic fields were measured adjacent to transformers and inverters, and radiofrequency fields from 5-100 kHz were associated with the inverters. The fields measured complied in every case with IEEE controlled and ICNIRP occupational exposure limits. In all cases, electric fields were negligible compared to IEEE and ICNIRP limits across the spectrum measured and when compared to the FCC limits (≥0.3 MHz).

Developing mobile- and BIM-based integrated visual facility maintenance management system.

PubMed

Lin, Yu-Cheng; Su, Yu-Chih

2013-01-01

Facility maintenance management (FMM) has become an important topic for research on the operation phase of the construction life cycle. Managing FMM effectively is extremely difficult owing to various factors and environments. One of the difficulties is the performance of 2D graphics when depicting maintenance service. Building information modeling (BIM) uses precise geometry and relevant data to support the maintenance service of facilities depicted in 3D object-oriented CAD. This paper proposes a new and practical methodology with application to FMM using BIM technology. Using BIM technology, this study proposes a BIM-based facility maintenance management (BIMFMM) system for maintenance staff in the operation and maintenance phase. The BIMFMM system is then applied in selected case study of a commercial building project in Taiwan to verify the proposed methodology and demonstrate its effectiveness in FMM practice. Using the BIMFMM system, maintenance staff can access and review 3D BIM models for updating related maintenance records in a digital format. Moreover, this study presents a generic system architecture and its implementation. The combined results demonstrate that a BIMFMM-like system can be an effective visual FMM tool.

Developing Mobile- and BIM-Based Integrated Visual Facility Maintenance Management System

PubMed Central

Su, Yu-Chih

2013-01-01

Facility maintenance management (FMM) has become an important topic for research on the operation phase of the construction life cycle. Managing FMM effectively is extremely difficult owing to various factors and environments. One of the difficulties is the performance of 2D graphics when depicting maintenance service. Building information modeling (BIM) uses precise geometry and relevant data to support the maintenance service of facilities depicted in 3D object-oriented CAD. This paper proposes a new and practical methodology with application to FMM using BIM technology. Using BIM technology, this study proposes a BIM-based facility maintenance management (BIMFMM) system for maintenance staff in the operation and maintenance phase. The BIMFMM system is then applied in selected case study of a commercial building project in Taiwan to verify the proposed methodology and demonstrate its effectiveness in FMM practice. Using the BIMFMM system, maintenance staff can access and review 3D BIM models for updating related maintenance records in a digital format. Moreover, this study presents a generic system architecture and its implementation. The combined results demonstrate that a BIMFMM-like system can be an effective visual FMM tool. PMID:24227995

A CLOSED-LOOP BIODIESEL PRODUCTION AND RESEARCH FACILITY IN KEENE, NH

EPA Science Inventory

The main objectives during Phase I were to continue a Biodiesel Working Group, formalize the organizational structure of the Monadnock Biodiesel Collaborative, identify a possible facility location, secure funding, provide novel curriculum for Keene State College students, and...

Posttest examination of Sodium Loop Safety Facility experiments. [LMFBR

DOE Office of Scientific and Technical Information (OSTI.GOV)

Holland, J.W.

In-reactor, safety experiments performed in the Sodium Loop Safety Facility (SLSF) rely on comprehensive posttest examinations (PTE) to characterize the postirradiation condition of the cladding, fuel, and other test-subassembly components. PTE information and on-line instrumentation data, are analyzed to identify the sequence of events and the severity of the accident for each experiment. Following in-reactor experimentation, the SLSF loop and test assembly are transported to the Hot Fuel Examination Facility (HFEF) for initial disassembly. Goals of the HFEF-phase of the PTE are to retrieve the fuel bundle by dismantling the loop and withdrawing the test assembly, to assess the macro-conditionmore » of the fuel bundle by nondestructive examination techniques, and to prepare the fuel bundle for shipment to the Alpha-Gamma Hot Cell Facility (AGHCF) at Argonne National Laboratory.« less

Opportunities for Energy Efficiency and Open Automated Demand Response in Wastewater Treatment Facilities in California -- Phase I Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lekov, Alex; Thompson, Lisa; McKane, Aimee

This report summarizes the Lawrence Berkeley National Laboratory?s research to date in characterizing energy efficiency and automated demand response opportunities for wastewater treatment facilities in California. The report describes the characteristics of wastewater treatment facilities, the nature of the wastewater stream, energy use and demand, as well as details of the wastewater treatment process. It also discusses control systems and energy efficiency and automated demand response opportunities. In addition, several energy efficiency and load management case studies are provided for wastewater treatment facilities.This study shows that wastewater treatment facilities can be excellent candidates for open automated demand response and thatmore » facilities which have implemented energy efficiency measures and have centralized control systems are well-suited to shift or shed electrical loads in response to financial incentives, utility bill savings, and/or opportunities to enhance reliability of service. Control technologies installed for energy efficiency and load management purposes can often be adapted for automated demand response at little additional cost. These improved controls may prepare facilities to be more receptive to open automated demand response due to both increased confidence in the opportunities for controlling energy cost/use and access to the real-time data.« less

DESIGN CRITERIA FOR FUEL DISSOLUTION SYSTEMS AND ASSOCIATED SERVICE FACILITIES. PLANT MODIFICATIONS FOR REPROCESSING NON-PRODUCTION REACTOR FUELS. PROJECT CGC-830

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bierman, S.R.; Graf, W.A.; Kass, M.

1960-07-29

Design panameters are presented for phases of the facility to reprocess low-enrichment fuels from nonproduction reactors. Included are plant flowsheets and equipment layouts for fuel element dissolution, centrifugation, solution adjustment, and waste handling. Also included are the basic design criteria for the supporting facilities which service these phases and all other facilites located in the vicinity of the selected building (Bldg. 221-U). (J.R.D.)

A Review of the Aging Process and Facilities Topic.

PubMed

Jornitz, Maik W

2015-01-01

Aging facilities have become a concern in the pharmaceutical and biopharmaceutical manufacturing industry, so much that task forces are formed by trade organizations to address the topic. Too often, examples of aging or obsolete equipment, unit operations, processes, or entire facilities have been encountered. Major contributors to this outcome are the failure to invest in new equipment, disregarding appropriate maintenance activities, and neglecting the implementation of modern technologies. In some cases, a production process is insufficiently modified to manufacture a new product in an existing process that was used to produce a phased-out product. In other instances, manufacturers expanded the facility or processes to fulfill increasing demand and the scaling occurred in a non-uniform manner, which led to non-optimal results. Regulatory hurdles of post-approval changes in the process may thwart companies' efforts to implement new technologies. As an example, some changes have required 4 years to gain global approval. This paper will address cases of aging processes and facilities aside from modernizing options. © PDA, Inc. 2015.

HISCAT: A proposed new scatter facility in Northern Scandinavia

NASA Technical Reports Server (NTRS)

Bostrom, R.; Thide, B.

1986-01-01

It is proposed that a new versatile ionospheric and atmospheric scatter radar be constructed in northern Scandavia through a multinational collaborative effort. The new facility tentatively named HISCAT (High frequency, High power, High latitude, Heating and Ionospheric Scatter facility), should be used for scientific investigations of: the physics of the neutral (middle) atmosphere; fundamental plasma phenomena, natural or artificially induced in the ionosphere; electrodynamic conditions at high altitudes above the auroral region and in the polar cap ionosphere; plasma waves in the solar atmosphere. The system should thus be able to operate as a mesosphere-stratosphere-troposphere (MST) radar, a so-called ionospheric modification facility, incoherent-scatter radar, coherent-scatter radar, and solar radar. Basically, the new facility should be a device that can operate simultaneously on several frequencies in the frequency range 5 to 50 MHz not covered by other instruments. It should comprise: powerful transmitters, capable of delivering a total average power of several megawatts; an advanced phased antenna array of high gain forming one or two steerable and well collimated beams; and an advanced data collection and analysis system.

Nanometer-scale characterization of laser-driven plasmas, compression, shocks and phase transitions, by coherent small angle x-ray scattering

NASA Astrophysics Data System (ADS)

Kluge, Thomas

2015-11-01

Combining ultra-intense short-pulse and high-energy long-pulse lasers, with brilliant coherent hard X-ray FELs, such as the Helmholtz International Beamline for Extreme Fields (HIBEF) under construction at the HED Instrument of European XFEL, or MEC at LCLS, holds the promise to revolutionize our understanding of many High Energy Density Physics phenomena. Examples include the relativistic electron generation, transport, and bulk plasma response, and ionization dynamics and heating in relativistic laser-matter interactions, or the dynamics of laser-driven shocks, quasi-isentropic compression, and the kinetics of phase transitions at high pressure. A particularly promising new technique is the use of coherent X-ray diffraction to characterize electron density correlations, and by resonant scattering to characterize the distribution of specific charge-state ions, either on the ultrafast time scale of the laser interaction, or associated with hydrodynamic motion. As well one can image slight density changes arising from phase transitions inside of shock-compressed high pressure matter. The feasibility of coherent diffraction techniques in laser-driven matter will be discussed. including recent results from demonstration experiments at MEC. Among other things, very sharp density changes from laser-driven compression are observed, having an effective step width of 10 nm or smaller. This compares to a resolution of several hundred nm achievedpreviously with phase contrast imaging. and on behalf of HIBEF User Consortium, for the Helmholtz International Beamline for Extreme Fields at the European XFEL.

Reliable Facility Location Problem with Facility Protection

PubMed Central

Tang, Luohao; Zhu, Cheng; Lin, Zaili; Shi, Jianmai; Zhang, Weiming

2016-01-01

This paper studies a reliable facility location problem with facility protection that aims to hedge against random facility disruptions by both strategically protecting some facilities and using backup facilities for the demands. An Integer Programming model is proposed for this problem, in which the failure probabilities of facilities are site-specific. A solution approach combining Lagrangian Relaxation and local search is proposed and is demonstrated to be both effective and efficient based on computational experiments on random numerical examples with 49, 88, 150 and 263 nodes in the network. A real case study for a 100-city network in Hunan province, China, is presented, based on which the properties of the model are discussed and some managerial insights are analyzed. PMID:27583542

Novel Out-Coupling Techniques for Terahertz Free Electron Lasers

DTIC Science & Technology

2012-06-01

4  1.   FEL “ Pendulum ” Equation and Electron Dynamics .......................4  2.   FEL...4 B. FEL THEORY 1. FEL “ Pendulum ” Equation and Electron Dynamics The dynamics of electron motion as it passes through the undulator are governed...I.5, then the FEL “ pendulum equation” is derived , (I.7) where is the dimensionless laser field amplitude[1]. From this, it is shown that changes

OPERATIONAL CHARACTERISTICS OF THE ARMOUR FISSION GAS GAMMA FACILITY

DOE Office of Scientific and Technical Information (OSTI.GOV)

Terrell, C.W.; McElroy, W.N.

1958-10-31

As the reactor power level is changed frequently, the radiation levels in the gamma facility fluctuate. Data are presented to show the power dependency of the gamma dose rate and the manner of growth and decay. Additional data show the dependercy of the equilibrium gamma activity on the foel temperature and total system pressure. The final phase of the work is directed toward determining an average gamma energy by attenuation measurements with various thicknesses of several materials. The neutrou flux associated with the gas phase activity is determined by foil measurement. From the measurements of dose rate and average gammamore » energy, calculations to determine the number of curies of gas phase decay gamma activity per watt of reactor power are presented. (auth)« less

Separation of Dynamics in the Free Energy Landscape

NASA Astrophysics Data System (ADS)

Ekimoto, Toru; Odagaki, Takashi; Yoshimori, Akira

2008-02-01

The dynamics of a representative point in a model free energy landscape (FEL) is analyzed by the Langevin equation with the FEL as the driving potential. From the detailed analysis of the generalized susceptibility, fast, slow and Johari-Goldstein (JG) processes are shown to be well described by the FEL. Namely, the fast process is determined by the stochastic motion confined in a basin of the FEL and the relaxation time is related to the curvature of the FEL at the bottom of the basin. The jump motion among basins gives rise to the slow relaxation whose relaxation time is determined by the distribution of the barriers in the FEL and the JG process is produced by weak modulation of the FEL.

Environmental assessment of the Carlsbad Environmental Monitoring and Research Center Facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1995-10-01

This Environmental Assessment has been prepared to determine if the Carlsbad Environmental Monitoring and Research Center (the Center), or its alternatives would have significant environmental impacts that must be analyzed in an Environmental Impact Statement. DOE`s proposed action is to continue funding the Center. While DOE is not funding construction of the planned Center facility, operation of that facility is dependent upon continued funding. To implement the proposed action, the Center would initially construct a facility of approximately 2,300 square meters (25,000 square feet). The Phase 1 laboratory facilities and parking lot will occupy approximately 1.2 hectares (3 acres) ofmore » approximately 8.9 hectares (22 acres) of land which were donated to New Mexico State University (NMSU) for this purpose. The facility would contain laboratories to analyze chemical and radioactive materials typical of potential contaminants that could occur in the environment in the vicinity of the DOE Waste Isolation Pilot Plant (WIPP) site or other locations. The facility also would have bioassay facilities to measure radionuclide levels in the general population and in employees of the WIPP. Operation of the Center would meet the DOE requirement for independent monitoring and assessment of environmental impacts associated with the planned disposal of transuranic waste at the WIPP.« less

30 CFR 285.629 - May I develop my lease in phases?

Code of Federal Regulations, 2010 CFR

2010-07-01

... RENEWABLE ENERGY ALTERNATE USES OF EXISTING FACILITIES ON THE OUTER CONTINENTAL SHELF Plans and Information Requirements Contents of the Construction and Operations Plan § 285.629 May I develop my lease in phases? In... operations and what portions of the lease will be reserved for subsequent phased development. ...

The ISOLDE facility and the HIE-HISOLDE project: Recent highlights

DOE Office of Scientific and Technical Information (OSTI.GOV)

Borge, M. J. G.

2014-07-23

The ISOLDE facility at CERN has as objective the production, study and research of nuclei far from stability. The facility provides low energy radioactive beams and post-accelerated beams. In the last 45 years the ISOLDE facility has gathered unique expertise in research with radioactive beams. Over 700 isotopes of more than 70 elements have been used in a wide range of research domains, including cutting edge studies in nuclear structure, atomic physics, nuclear astrophysics, and fundamental interactions. These nuclear probes are also used to do frontier research in solid state and life sciences. There is an on-going upgrade of themore » facility, the HIE-ISOLDE project, which aims to improve the ISOLDE capabilities in a wide front, from an energy increase of the post-accelerated beam to improvements in beam quality and beam purity. The first phase of HIE-ISOLDE will start for physics in the autumn of 2015 with an upgrade of energy for all post-accelerated ISOLDE beams up to 5.5 MeV/u. In this contribution the most recent highlights of the facility are presented.« less

Modifications to ART service delivery models by health facilities in Uganda in promotion of intervention sustainability: a mixed methods study.

PubMed

Zakumumpa, Henry; Bennett, Sara; Ssengooba, Freddie

2017-04-04

In November 2015, WHO released new treatment guidelines recommending that all diagnosed as HIV positive be enrolled on antiretroviral therapy (ART). Sustaining and expanding ART scale-up programs in resource-limited settings will require adaptations and modifications to traditional ART delivery models to meet the rapid increase in demand. We identify modifications to ART service delivery models by health facilities in Uganda to sustain ART interventions over a 10-year period (2004-2014). A mixed methods approach involving two study phases was adopted. In the first phase, a survey of a nationally representative sample of health facilities (n = 195) in Uganda which were accredited to provide ART between 2004 and 2009 was conducted. The second phase involved semi-structured interviews (n = 18) with ART clinic managers of 6 of the 195 health facilities purposively selected from the first study phase. We adopted a thematic framework consisting of four categories of modifications (format, setting, personnel, and population). The majority of health facilities 185 (95%) reported making modifications to ART interventions between 2004 and 2014. Of the 195 health facilities, 157 (81%) rated the modifications made to ART as "major." Modifications to ART were reported under all the four themes. The quantitative and qualitative findings are integrated and presented under four themes. Format: Reducing the frequency of clinic appointments and pharmacy-only refill programs was identified as important strategies for decongesting ART clinics. Home-based care programs were introduced to reduce provider ART delivery costs. Personnel: Task shifting to non-physician cadre was reported in 181 (93%) of the health facilities. Visits to the ART clinic were rationalized in favor of the sub-population deemed to have more clinical need. Two health facilities focused on patients living nearer the health facilities to align with targets set by external donors. Over the study period

Pubertal pathways and the relationship to anthropometric changes in childhood: The Fels longitudinal study

PubMed Central

Wan, Wen; Deng, Xiaoyan; Archer, Kellie J.; Sun, Shumei S.

2013-01-01

Objective To examine the relationship of the initial manifestation of pubertal development in children to anthropometric measurements recorded during the early childhood and adolescence. Methods The Fels Longitudinal study is an observational study of growth and development of healthy white children. A total of 109 boys and 75 girls with serial self-assessments of Tanner stages of genital/breast and pubic hair developments provided data for a longitudinal analysis with a linear mixed model. Results About 11.0% of boys and 22.7% of girls witnessed the appearance of pubic hair (adrenarche) prior to the onset of genital/breast growth (gonadarche/thelarche) and about 13.7% of boys and 22.7% of girls experienced the onset of gonadarche/thelarche prior to adrenarche. The remaining 75.3% of boys and 54.7% of girls were concordant for adrenarche and gonadarche/thelarche. During the first two years of life, boys and girls with earlier gonadarche and thelarche than adrenarche were found to have more rapid weight gain than those with earlier adrenarche than gonadarche/thelarche. During early childhood from age 2 – 7 years, those girls with early thelarche had higher body mass index (BMI) and waist circumference to height ratio (waist/height) than those with early adrenarche. In children of ages 8 – 20, girls with early gonadarche had higher BMI z-scores than those with early adrenarche. Conclusion Girls with early thelarche and later adrenarche, have more rapid mean weight gain during the first two years of life, higher BMI and waist/height during early childhood, and higher BMI z-scores during adolescence. Boys with early gonadarche and later adrenarche experienced more rapid weight gain during the first two years of life than boys with early adrenarche and later gonadarche. In other words, girls with early thelarche are more likely to be triggered by early accumulation of fat mass than those with early adrenarche. PMID:24307981

Simplified spacecraft vulnerability assessments at component level in early design phase at the European Space Agency's Concurrent Design Facility

NASA Astrophysics Data System (ADS)

Kempf, Scott; Schäfer, Frank K.; Cardone, Tiziana; Ferreira, Ivo; Gerené, Sam; Destefanis, Roberto; Grassi, Lilith

2016-12-01

During recent years, the state-of-the-art risk assessment of the threat posed to spacecraft by micrometeoroids and space debris has been expanded to the analysis of failure modes of internal spacecraft components. This method can now be used to perform risk analyses for satellites to assess various failure levels - from failure of specific sub-systems to catastrophic break-up. This new assessment methodology is based on triple-wall ballistic limit equations (BLEs), specifically the Schäfer-Ryan-Lambert (SRL) BLE, which is applicable for describing failure threshold levels for satellite components following a hypervelocity impact. The methodology is implemented in the form of the software tool Particle Impact Risk and vulnerability Analysis Tool (PIRAT). During a recent European Space Agency (ESA) funded study, the PIRAT functionality was expanded in order to provide an interface to ESA's Concurrent Design Facility (CDF). The additions include a geometry importer and an OCDT (Open Concurrent Design Tool) interface. The new interface provides both the expanded geometrical flexibility, which is provided by external computer aided design (CAD) modelling, and an ease of import of existing data without the need for extensive preparation of the model. The reduced effort required to perform vulnerability analyses makes it feasible for application during early design phase, at which point modifications to satellite design can be undertaken with relatively little extra effort. The integration of PIRAT in the CDF represents the first time that vulnerability analyses can be performed in-session in ESA's CDF and the first time that comprehensive vulnerability studies can be applied cost-effectively in early design phase in general.

Generation of double pulses at the Shanghai soft X-ray free electron laser facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Zhen; Feng, Chao; Gu, Qiang

2017-01-28

In this paper, we present the promise of a new method generating double electron pulses with the picosecond-scale pulse length and the tunable interpulse spacing at several picoseconds, which has been witnessed an impressive potential of application in pump-probe techniques, two-color X-ray free electron laser (FEL), high-gradient witness bunch acceleration in a plasma, etc. Three-dimensional simulations are carried out to analyze the dynamic of the electron beam in the linear accelerator. Some comparisons have been made between the new method and the existing ways as well.

Project report : road weather information system phase I

DOT National Transportation Integrated Search

2004-11-01

The Alaska Department of Transportation & Public Facilities (ADOT&PF) initiated the first eight environmental sensor stations (ESS) in the Anchorage area, called the Road Weather Information System (RWIS) Phase I. The ESS are used to detect road weat...

Aspheric figure generation using feedback from an infrared phase-shifting interferometer

NASA Astrophysics Data System (ADS)

Stahl, H. P.; Ketelsen, D.

An infrared phase-shifting interferometric system has been integrated with a novel optical figure generator at the University of Arizona Optical Sciences Center. This unique generator facility can produce generalized axially symmetric surface figures in a timely and cost-effective manner. The success of this facility depends on both its ability to efficiently remove material while forming the surface figure, and its ability to monitor the surface figure during the generation process to provide feedback to the optician. The facility has been used on several occasions to custom-generate off-axis parabolic segments. Figures to within 0.30 microns rms of the desired figure have been obtained. This paper discusses the usefulness of the infrared phase-shifting interferometric system for providing figure correcting feedback to the optician during the generation of the off-axis parabolic segments, and how it is affected by the surface roughness produced by each generator tool.

Decontamination and decommissioning of the Mayaguez (Puerto Rico) facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jackson, P.K.; Freemerman, R.L.

1989-11-01

On February 6, 1987 the US Department of Energy (DOE) awarded the final phase of the decontamination and decommissioning of the nuclear and reactor facilities at the Center for Energy and Environmental Research (CEER), in Mayaguez, Puerto Rico. Bechtel National, Inc., was made the decontamination and decommissioning (D and D) contractor. The goal of the project was to enable DOE to proceed with release of the CEER facility for use by the University of Puerto Rico, who was the operator. This presentation describes that project and lesson learned during its progress. The CEER facility was established in 1957 as themore » Puerto Rico Nuclear Center, a part of the Atoms for Peace Program. It was a nuclear training and research institution with emphasis on the needs of Latin America. It originally consisted of a 1-megawatt Materials Testing Reactor (MTR), support facilities and research laboratories. After eleven years of operation the MTR was shutdown and defueled. A 2-megawatt TRIGA reactor was installed in 1972 and operated until 1976, when it woo was shutdown. Other radioactive facilities at the center included a 10-watt homogeneous L-77 training reactor, a natural uranium graphite-moderated subcritical assembly, a 200KV particle accelerator, and a 15,000 Ci Co-60 irradiation facility. Support facilities included radiochemistry laboratories, counting rooms and two hot cells. As the emphasis shifted to non-nuclear energy technology a name change resulted in the CEER designation, and plans were started for the decontamination and decommissioning effort.« less

National Ignition Facility project acquisition plan

DOE Office of Scientific and Technical Information (OSTI.GOV)

Callaghan, R.W.

The purpose of this National Ignition Facility Acquisition Plan is to describe the overall procurement strategy planned for the National Ignition Facility (NIF) Project. The scope of the plan describes the procurement activities and acquisition strategy for the following phases of the NIF Project, each of which receives either plant and capital equipment (PACE) or other project cost (OPC) funds: Title 1 and 2 design and Title 3 engineering (PACE); Optics manufacturing facilitization and pilot production (OPC); Convention facility construction (PACE); Procurement, installation, and acceptance testing of equipment (PACE); and Start-up (OPC). Activities that are part of the base Inertialmore » Confinement Fusion (ICF) Program are not included in this plan. The University of California (UC), operating Lawrence Livermore National Laboratory (LLNL) and Los Alamos National Laboratory, and Lockheed-Martin, which operates Sandia National Laboratory (SNL) and the University of Rochester Laboratory for Laser Energetics (UR-LLE), will conduct the acquisition of needed products and services in support of their assigned responsibilities within the NIF Project structure in accordance with their prime contracts with the Department of Energy (DOE). LLNL, designated as the lead Laboratory, will have responsibility for all procurements required for construction, installation, activation, and startup of the NIF.« less

Final work plan : investigation of potential contamination at the former CCC/USDA grain storage facility in Hanover, Kansas.

DOE Office of Scientific and Technical Information (OSTI.GOV)

LaFreniere, L. M.; Environmental Science Division

Science Division of Argonne National Laboratory. Argonne is a nonprofit, multidisciplinary research center operated by UChicago Argonne, LLC, for the U.S. Department of Energy (DOE). The CCC/USDA has entered into an interagency agreement with DOE, under which Argonne provides technical assistance to the CCC/USDA with environmental site characterization and remediation at its former grain storage facilities. Seven technical objectives have been proposed for the Hanover investigation. They are as follows: (1) Identify the sources and extent of soil contamination beneath the former CCC/USDA facility; (2) Characterize groundwater contamination beneath the former CCC/USDA facility; (3) Determine groundwater flow patterns; (4) Define the vertical and lateral extent of the groundwater plume outside the former CCC/USDA facility; (5) Evaluate the aquifer and monitor the groundwater system; (6) Identify any other potential sources of contamination that are not related to activities of the CCC/USDA; and (7) Determine whether there is a vapor intrusion problem at the site attributable to the former CCC/USDA facility. The technical objectives will be accomplished in a phased approached. Data collected during each phase will be evaluated to determine whether the subsequent phase is necessary. The KDHE project manager and the CCC/USDA will be contacted during each phase and kept apprised of the results. Whether implementation of each phase of work is necessary will be discussed and mutually agreed upon by the CCC/USDA and KDHE project managers.« less

Dual-scale phase-field simulation of Mg-Al alloy solidification

NASA Astrophysics Data System (ADS)

Monas, A.; Shchyglo, O.; Höche, D.; Tegeler, M.; Steinbach, I.

2015-06-01

Phase-field simulations of the nucleation and growth of primary α-Mg phase as well as secondary, β-phase of a Mg-Al alloy are presented. The nucleation model for α- and β-Mg phases is based on the “free growth model” by Greer et al.. After the α-Mg phase solidification we study a divorced eutectic growth of α- and β-Mg phases in a zoomed in melt channel between α-phase dendrites. The simulated cooling curves and final microstructures of α-grains are compared with experiments. In order to further enhance the resolution of the interdendritic region a high-performance computing approach has been used allowing significant simulation speed gain when using supercomputing facilities.

Advanced Simulation in Undergraduate Pilot Training (ASUPT) Facility Utilization Plan.

ERIC Educational Resources Information Center

Hagin, William V.; Smith, James F.

The capabilities of a flight simulation research facility located at Williams AFB, Arizona are described. Research philosophy to be applied is discussed. Long range and short range objectives are identified. A time phased plan for long range research accomplishment is described. In addition, some examples of near term research efforts which will…

HIFiRE Direct-Connect Rig (HDCR) Phase I Ground Test Results from the NASA Langley Arc-Heated Scramjet Test Facility

NASA Technical Reports Server (NTRS)

Hass, Neal E.; Cabell, Karen F.; Storch, Andrea M.

2010-01-01

The initial phase of hydrocarbon-fueled ground tests supporting Flight 2 of the Hypersonic International Flight Research Experiment (HIFiRE) Program has been conducted in the NASA Langley Arc-Heated Scramjet Test Facility (AHSTF). The HIFiRE Program, an Air Force-lead international cooperative program includes eight different flight test experiments designed to target specific challenges of hypersonic flight. The second of the eight planned flight experiments is a hydrocarbon-fueled scramjet flight test intended to demonstrate dual-mode to scramjet-mode operation and verify the scramjet performance prediction and design tools. A performance goal is the achievement of a combusted fuel equivalence ratio greater than 0.7 while in scramjet mode. The ground test rig, designated the HIFiRE Direct Connect Rig (HDCR), is a full-scale, heat sink, direct-connect ground test article that duplicates both the flowpath lines and the instrumentation layout of the isolator and combustor portion of the flight test hardware. The primary objectives of the HDCR Phase I tests are to verify the operability of the HIFiRE isolator/combustor across the Mach 6.0-8.0 flight regime and to establish a fuel distribution schedule to ensure a successful mode transition prior to the HiFIRE payload Critical Design Review. Although the phase I test plans include testing over the Mach 6 to 8 flight simulation range, only Mach 6 testing will be reported in this paper. Experimental results presented here include flowpath surface pressure, temperature, and heat flux distributions that demonstrate the operation of the flowpath over a small range of test conditions around the nominal Mach 6 simulation, as well as a range of fuel equivalence ratios and fuel injection distributions. Both ethylene and a mixture of ethylene and methane (planned for flight) were tested. Maximum back pressure and flameholding limits, as well as a baseline fuel schedule, that covers the Mach 5.84-6.5 test space have been

Work Plan: Phase II Investigation at the Former CCC/USDA Grain Storage Facility in Montgomery City, Missouri

DOE Office of Scientific and Technical Information (OSTI.GOV)

LaFreniere, Lorraine M

From September 1949 until September 1966, the Commodity Credit Corporation of the U.S. Department of Agriculture (CCC/USDA) leased property at the southeastern end of Montgomery City, Missouri, for the operation of a grain storage facility. During this time, commercial grain fumigants containing carbon tetrachloride were commonly used by the CCC/USDA and the private grain storage industry to preserve grain in their facilities.

Facilities and the Air Force Systems Acquisition Process.

DTIC Science & Technology

1985-05-01

INSTRUMENT IDENTIFICATION NUMBER ORGANIZATION (it applicable) Sc. ADDRESS (City. State and ZIP Code) 10. SOURCE OF FUNDING NOS. PROGRAM PROJECT TASK WORK UNIT...L- . - - - CHAP T-F< I P f),DUCTr JOti The Air Force is in the midst of its most extensive peacetime force modernization programs ...will answer the following ques- tions: a. Are facility requirements anticipated and ade- quatel% scoped during the early phase of program development so

Thermal Vacuum Facility for Testing Thermal Protection Systems

NASA Technical Reports Server (NTRS)

Daryabeigi, Kamran; Knutson, Jeffrey R.; Sikora, Joseph G.

2002-01-01

A thermal vacuum facility for testing launch vehicle thermal protection systems by subjecting them to transient thermal conditions simulating re-entry aerodynamic heating is described. Re-entry heating is simulated by controlling the test specimen surface temperature and the environmental pressure in the chamber. Design requirements for simulating re-entry conditions are briefly described. A description of the thermal vacuum facility, the quartz lamp array and the control system is provided. The facility was evaluated by subjecting an 18 by 36 in. Inconel honeycomb panel to a typical re-entry pressure and surface temperature profile. For most of the test duration, the average difference between the measured and desired pressures was 1.6% of reading with a standard deviation of +/- 7.4%, while the average difference between measured and desired temperatures was 7.6% of reading with a standard deviation of +/- 6.5%. The temperature non-uniformity across the panel was 12% during the initial heating phase (t less than 500 sec.), and less than 2% during the remainder of the test.

On-cartridge derivatisation using a calixarene solid-phase extraction sorbent for facile, sensitive and fast determination of formaldehyde in beer.

PubMed

Deng, Zhifen; Hu, Kai; Zhang, Yongming; Zhao, Wenjie; Wang, Fei; Guo, Ling; Zhang, Wenfen; He, Juan; Huang, Yanjie; Zhang, Shusheng

2016-11-15

This work demonstrates the successful application of an on-cartridge derivatisation procedure for facile, fast and sensitive determination of formaldehyde in beer by HPLC-UV. The derivatisation and solid-phase extraction (SPE) were integrated into a novel calixarene SPE sorbent: tetraazacalix[2]arene[2]triazine bonded silica gel. Specifically, 2,4-dinitrophenylhydrazine was adsorbed onto the sorbent in advance, based on the charge-transfer interaction between the macrocyclic molecule and nitrobenzenes. The method was optimised and validated: under the optimal conditions of derivatisation, SPE and HPLC separation, good linearity was obtained in the range of 0.080-3.2μgmL(-1) with a correlation coefficient of 0.9939, the limit of detection was 3.0ngmL(-1) (S/N=3), the limit of quantification was 10ngmL(-1) (S/N=10), and the recovery level using this method was desirable at 75-84%. The developed method was successfully applied to determine formaldehyde content in real beer samples; the results were in the range of 0.11-1.1μgmL(-1). Copyright © 2016. Published by Elsevier Ltd.

Visualizing deceleration-phase instabilities in inertial confinement fusion implosions using an "enhanced self-emission" technique at the National Ignition Facility

NASA Astrophysics Data System (ADS)

Pickworth, L. A.; Hammel, B. A.; Smalyuk, V. A.; Robey, H. F.; Benedetti, L. R.; Berzak Hopkins, L.; Bradley, D. K.; Field, J. E.; Haan, S. W.; Hatarik, R.; Hartouni, E.; Izumi, N.; Johnson, S.; Khan, S.; Lahmann, B.; Landen, O. L.; Le Pape, S.; MacPhee, A. G.; Meezan, N. B.; Milovich, J.; Nagel, S. R.; Nikroo, A.; Pak, A. E.; Petrasso, R.; Remington, B. A.; Rice, N. G.; Springer, P. T.; Stadermann, M.; Widmann, K.; Hsing, W.

2018-05-01

High-mode perturbations and low-mode asymmetries were measured in the deceleration phase of indirectly driven, deuterium gas filled inertial confinement fusion capsule implosions at convergence ratios of 10 to 15, using a new "enhanced emission" technique at the National Ignition Facility [E. M. Campbell et al., AIP Conf. Proc. 429, 3 (1998)]. In these experiments, a high spatial resolution Kirkpatrick-Baez microscope was used to image the x-ray emission from the inner surface of a high-density-carbon capsule's shell. The use of a high atomic number dopant in the shell enabled time-resolved observations of shell perturbations penetrating into the hot spot. This allowed the effects of the perturbations and asymmetries on degrading neutron yield to be directly measured. In particular, mix induced radiation losses of ˜400 J from the hot spot resulted in a neutron yield reduction of a factor of ˜2. In a subsequent experiment with a significantly increased level of short-mode initial perturbations, shown through the enhanced imaging technique to be highly organized radially, the neutron yield dropped an additional factor of ˜2.

Quantitative measurement of IgE antibodies to purified allergens using streptavidin linked to a high-capacity solid phase.

PubMed

Erwin, Elizabeth A; Custis, Natalie J; Satinover, Shama M; Perzanowski, Matthew S; Woodfolk, Judith A; Crane, Julian; Wickens, Kristin; Platts-Mills, Thomas A E

2005-05-01

Commercially available assays for IgE antibody provide results in international units per milliliter for many allergen extracts, but this is not easily achieved with purified or novel allergens. To develop assays for IgE antibody suitable for purified or novel allergens by using a commercially available immunosorbent. Streptavidin coupled to a high-capacity immunosorbent (CAP) was used to bind biotinylated purified allergens from mite (Der p 1 and Der p 2), cat (Fel d 1), and dog (Can f 1). Assays for IgE antibody to these allergens were performed on sera from children (asthma and control) as well as adults with atopic dermatitis. The results were validated by serial dilution of sera with high and low levels of IgE antibody and were quantitated in international units per milliliter by using a standard curve. Values for IgE antibody to Der p 1, Der p 2, and Fel d 1 correlated with values obtained with the allergen extracts (r2 = 0.80, 0.84, and 0.95, respectively; P < .001 in each case). Furthermore, the values for IgE antibody in sera from children with high exposure to mite and cat allergens demonstrated 10-fold higher levels of IgE antibody to Der p 1 and Der p 2 than to Fel d 1 (P < .001). The streptavidin immunosorbent technique provides a new method for quantifying IgE antibody to purified proteins. The results provide evidence about the high quantities of IgE antibody to purified inhalant allergens in patients with atopic dermatitis. In addition, the results demonstrate major differences in IgE antibodies specific for mite and cat allergens among children with high exposure to both allergens.

Life-Cycle Assessments of Selected NASA Ground-Based Test Facilities

NASA Technical Reports Server (NTRS)

Sydnor, George Honeycutt

2012-01-01

In the past two years, two separate facility-specific life cycle assessments (LCAs) have been performed as summer student projects. The first project focused on 13 facilities managed by NASA s Aeronautics Test Program (ATP), an organization responsible for large, high-energy ground test facilities that accomplish the nation s most advanced aerospace research. A facility inventory was created for each facility, and the operational-phase carbon footprint and environmental impact were calculated. The largest impacts stemmed from electricity and natural gas used directly at the facility and to generate support processes such as compressed air and steam. However, in specialized facilities that use unique inputs like R-134a, R-14, jet fuels, or nitrogen gas, these sometimes had a considerable effect on the facility s overall environmental impact. The second LCA project was conducted on the NASA Ames Arc Jet Complex and also involved creating a facility inventory and calculating the carbon footprint and environmental impact. In addition, operational alternatives were analyzed for their effectiveness at reducing impact. Overall, the Arc Jet Complex impact is dominated by the natural-gas fired boiler producing steam on-site, but alternatives were provided that could reduce the impact of the boiler operation, some of which are already being implemented. The data and results provided by these LCA projects are beneficial to both the individual facilities and NASA as a whole; the results have already been used in a proposal to reduce carbon footprint at Ames Research Center. To help future life cycle projects, several lessons learned have been recommended as simple and effective infrastructure improvements to NASA, including better utility metering and data recording and standardization of modeling choices and methods. These studies also increased sensitivity to and appreciation for quantifying the impact of NASA s activities.

Multicascade X-Ray Free-Electron Laser with Harmonic Multiplier and Two-Frequency Undulator

NASA Astrophysics Data System (ADS)

Zhukovsky, K. V.

2018-06-01

The feasibility of generation of powerful x-ray radiation by a cascade free-electron laser (FEL) with amplification of higher harmonics using a two-frequency undulator is studied. To analyze the FEL operation, a complex phenomenological single-pass FEL model is developed and used. It describes linear and nonlinear generation of harmonics in the FEL with seed laser that takes into account initial electron beam noise and describes all main losses of each harmonic in each FEL cascade. The model is also calibrated against and approved by the experimental FEL data and available results of three-dimensional numerical simulation. The electron beam in the undulator is assumed to be matched and focused, and the dynamics of power in the singlepass FEL with cascade harmonic multipliers is investigated to obtain x-ray laser radiation in the FEL having the shortest length, beam energy, and frequency of the seed laser as low as possible. In this context, the advantages of the two-frequency undulator used for generation of harmonics are demonstrated. The evolution of harmonics in a multicascade FEL with multiplication of harmonics is investigated. The operation of the cascade FEL at the wavelength λ = 1.14 nm, generating 30 MW already on 38 m with the seed laser operating at a wavelength of 11.43 nm corresponding to the maximal reflectivity of the multilayered mirror MoRu/Be coating is investigated. In addition, the operation of the multicascade FEL with accessible seed UVlaser operating at a wavelength of 157 nm (F2 excimer UV-laser) and electron beam with energy of 0.5 GeV is investigated. X-ray radiation simulated in it at the wavelength λ 3.9 nm reaches power of 50 MW already at 27 m, which is by two orders of magnitude shorter than 3.4 km of the x-ray FEL recently put into operation in Europe.

Dance Facilities.

ERIC Educational Resources Information Center

Ashton, Dudley, Ed.; Irey, Charlotte, Ed.

This booklet represents an effort to assist teachers and administrators in the professional planning of dance facilities and equipment. Three chapters present the history of dance facilities, provide recommended dance facilities and equipment, and offer some adaptations of dance facilities and equipment, for elementary, secondary and college level…

TA 55 Reinvestment Project II Phase C Update Project Status May 23, 2017

DOE Office of Scientific and Technical Information (OSTI.GOV)

Giordano, Anthony P.

The TA-55 Reinvestment Project (TRP) II Phase C is a critical infrastructure project focused on improving safety and reliability of the Los Alamos National Laboratory (LANL) TA-55 Complex. The Project recapitalizes and revitalizes aging and obsolete facility and safety systems providing a sustainable nuclear facility for National Security Missions.

[CERN-MEDICIS (Medical Isotopes Collected from ISOLDE): a new facility].

PubMed

Viertl, David; Buchegger, Franz; Prior, John O; Forni, Michel; Morel, Philippe; Ratib, Osman; Bühler Léo H; Stora, Thierry

2015-06-17

CERN-MEDICIS is a facility dedicated to research and development in life science and medical applications. The research platform was inaugurated in October 2014 and will produce an increasing range of innovative isotopes using the proton beam of ISOLDE for fundamental studies in cancer research, for new imaging and therapy protocols in cell and animal models and for preclinical trials, possibly extended to specific early phase clinical studies (phase 0) up to phase I trials. CERN, the University Hospital of Geneva (HUG), the University Hospital of Lausanne (CHUV), the Swiss Institute for Experimental Cancer (ISREC) at Swiss Federal Institutes of Technology (EPFL) that currently support the project will benefit of the initial production that will then be extended to other centers.

Fire safety design of a mobile quarantine facility

NASA Technical Reports Server (NTRS)

Bass, R. S.; Hirasaki, J. K.

1971-01-01

During the design phase of the Mobile Quarantine Facility (MQF), a primary consideration was fire safety. Therefore, appropriate criteria and ground rules were used in the design and construction of the facility. The fire codes and fire-requirement listings that are used by commerical airlines were supplied to the Manned Spacecraft Center (MSC) by the Federal Aviation Agency (FAA). After these codes were reviewed, a basic ground rule was adopted that flame protection for all combustible materials should be at least equivalent to or better than the standards for commercial aircraft. Because the MQF was designed to operate with an interior atmosphere of air rather than with an oxygen-enriched atmosphere such as that of the Apollo spacecraft cabin, the requirements for MQF material were not as stringent as those for the spacecraft.

Pulsed laser illumination of photovoltaic cells

NASA Technical Reports Server (NTRS)

Yater, Jane A.; Lowe, Roland A.; Jenkins, Phillip P.; Landis, Geoffrey A.

1994-01-01

In future space missions, free electron lasers (FEL) may be used to illuminate photovoltaic array receivers to provide remote power. Both the radio-frequency (RF) and induction FEL provide FEL produce pulsed rather than continuous output. In this work we investigate cell response to pulsed laser light which simulates the RF FEL format. The results indicate that if the pulse repetition is high, cell efficiencies are only slightly reduced compared to constant illumination at the same wavelength. The frequency response of the cells is weak, with both voltage and current outputs essentially dc in nature. Comparison with previous experiments indicates that the RF FEL pulse format yields more efficient photovoltaic conversion than does an induction FEL pulse format.

Implementation of the next-generation Gas Cherenkov Detector at the National Ignition Facility

NASA Astrophysics Data System (ADS)

Carrera, J. A.; Herrmann, H. W.; Khater, H. Y.; Carpenter, A. C.; Beeman, B. V.; Hernandez, J. E.; Sitaraman, S.; Lopez, F. E.; Zylstra, A. B.; Griego, J. R.; Kim, Y. H.; Gales, S. A.; Horsfield, C. J.; Milnes, J. S.; Hares, J. D.

2017-08-01

The newest Gas Cherenkov Detector (GCD-3) diagnostic has completed its Phase I commissioning/milestone at the National Ignition Facility (NIF). GCD-3 was fielded for several years at the Omega Laser Facility in its initial configuration, before being moved to the NIF. Installation at the NIF involved optimization of GCD-3 for the higher background environment and designing a new insertion carrier assembly. GCD-3 serves as the initial phase towards the implementation of the "Super GCD" (SGCD) at the NIF. During this phase of development GCD-3 took measurements from a re-entrant well, 3.9 meters from target chamber center (TCC). Plans to insert GCD-3 within 20 cm of TCC with a Target and Diagnostic Manipulator (TANDM) will be discussed. Data was collected using a Photomultiplier Tube (PMT) in combination with a Mach-Zehnder based recording system. These measurements were used to aid in shielding analysis, validate MCNP models, and fuel design efforts for the SGCD. Findings from the initial data will be covered extensively, including an in-depth look into sources of background and possible mitigation strategies. Ongoing development of phase two, the addition of an ultra-high bandwidth Pulse Dilatation Photomultiplier Tube (PD-PMT), will also be presented.

Constellation Training Facility Support

NASA Technical Reports Server (NTRS)

Flores, Jose M.

2008-01-01

The National Aeronautics and Space Administration is developing the next set of vehicles that will take men back to the moon under the Constellation Program. The Constellation Training Facility (CxTF) is a project in development that will be used to train astronauts, instructors, and flight controllers on the operation of Constellation Program vehicles. It will also be used for procedure verification and validation of flight software and console tools. The CxTF will have simulations for the Crew Exploration Vehicle (CEV), Crew Module (CM), CEV Service Module (SM), Launch Abort System (LAS), Spacecraft Adapter (SA), Crew Launch Vehicle (CLV), Pressurized Cargo Variant CM, Pressurized Cargo Variant SM, Cargo Launch Vehicle, Earth Departure Stage (EDS), and the Lunar Surface Access Module (LSAM). The Facility will consist of part-task and full-task trainers, each with a specific set of mission training capabilities. Part task trainers will be used for focused training on a single vehicle system or set of related systems. Full task trainers will be used for training on complete vehicles and all of its subsystems. Support was provided in both software development and project planning areas of the CxTF project. Simulation software was developed for the hydraulic system of the Thrust Vector Control (TVC) of the ARES I launch vehicle. The TVC system is in charge of the actuation of the nozzle gimbals for navigation control of the upper stage of the ARES I rocket. Also, software was developed using C standards to send and receive data to and from hand controllers to be used in CxTF cockpit simulations. The hand controllers provided movement in all six rotational and translational axes. Under Project Planning & Control, support was provided to the development and maintenance of integrated schedules for both the Constellation Training Facility and Missions Operations Facilities Division. These schedules maintain communication between projects in different levels. The Cx

NASA Construction of Facilities Validation Processes - Total Building Commissioning (TBCx)

NASA Technical Reports Server (NTRS)

Hoover, Jay C.

2004-01-01

Key Atributes include: Total Quality Management (TQM) System that looks at all phases of a project. A team process that spans boundaries. A Commissioning Authority to lead the process. Commissioning requirements in contracts. Independent design review to verify compliance with Facility Project Requirements (FPR). Formal written Commissioning Plan with Documented Results. Functional performance testing (FPT) against the requirements document.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yan, J.; Hao, H.; Li, J. Y.

We report a systematic experimental study of a storage ring two-color free-electron laser (FEL) operating simultaneously in the infrared (IR) and ultraviolet (UV) wavelength regions. The two-color FEL lasing has been realized using a pair of dual-band high-reflectivity FEL mirrors with two different undulator configurations. We have demonstrated independent wavelength tuning in a wide range for each lasing color, as well as harmonically locked wavelength tuning when the UV lasing occurs at the second harmonic of the IR lasing. Precise power control of two-color lasing with good power stability has also been achieved. In addition, the impact of the degradationmore » of FEL mirrors on the two-color FEL operation is reported. Moreover, we have investigated the temporal structures of the two-color FEL beams, showing simultaneous two-color micropulses with their intensity modulations displayed as FEL macropulses.« less

Storage ring two-color free-electron laser

DOE PAGES

Yan, J.; Hao, H.; Li, J. Y.; ...

2016-07-05

We report a systematic experimental study of a storage ring two-color free-electron laser (FEL) operating simultaneously in the infrared (IR) and ultraviolet (UV) wavelength regions. The two-color FEL lasing has been realized using a pair of dual-band high-reflectivity FEL mirrors with two different undulator configurations. We have demonstrated independent wavelength tuning in a wide range for each lasing color, as well as harmonically locked wavelength tuning when the UV lasing occurs at the second harmonic of the IR lasing. Precise power control of two-color lasing with good power stability has also been achieved. In addition, the impact of the degradationmore » of FEL mirrors on the two-color FEL operation is reported. Moreover, we have investigated the temporal structures of the two-color FEL beams, showing simultaneous two-color micropulses with their intensity modulations displayed as FEL macropulses.« less

Novosibirsk Free Electron Laser: Recent Achievements and Future Prospects

NASA Astrophysics Data System (ADS)

Shevchenko, O. A.; Arbuzov, V. S.; Vinokurov, N. A.; Vobly, P. D.; Volkov, V. N.; Getmanov, Ya. V.; Davidyuk, I. V.; Deychuly, O. I.; Dementyev, E. N.; Dovzhenko, B. A.; Knyazev, B. A.; Kolobanov, E. I.; Kondakov, A. A.; Kozak, V. R.; Kozyrev, E. V.; Kubarev, V. V.; Kulipanov, G. N.; Kuper, E. A.; Kuptsov, I. V.; Kurkin, G. Ya.; Krutikhin, S. A.; Medvedev, L. E.; Motygin, S. V.; Ovchar, V. K.; Osipov, V. N.; Petrov, V. M.; Pilan, A. M.; Popik, V. M.; Repkov, V. V.; Salikova, T. V.; Sedlyarov, I. K.; Serednyakov, S. S.; Skrinsky, A. N.; Tararyshkin, S. V.; Tribendis, A. G.; Cheskidov, V. G.; Chernov, K. N.; Shcheglov, M. A.

2017-01-01

Free electron lasers (FELs) are unique sources of electromagnetic radiation with tunable wavelength. A high-power FEL has been created at the G. I.Budker Institute for Nuclear Physics. Its radiation frequency can be tuned over a wide range in the terahertz and infrared spectral ranges. As the source of electron bunches, this FEL uses a multi-turn energy-recovery linac, which has five straight sections. Three sections are used for three FELs which operate in different wavelength ranges (90-240 μm for the first, 37-80 μm for the second, and 5-20 μm for the third ones). The first and the second FELs were commissioned in 2003 and 2009, respectively. They are used for various applied and research problems now. The third FEL is installed on the last, forth accelerator loop, in which the electron energy is the maximum. It comprises three undulator sections and a 40 m optical cavity. The first lasing of this FEL was obtained in the summer of 2015. The radiation wavelength was 9 μm and the average power was about 100 W. The design power is 1 kW at a pulse repetition rate of 3.75 MHz. Radiation of the third FEL will be delivered to user stations from the protected hall in the near future. The third FEL commissioning results are presented and the current status of the first and second FELs as well as their future development prospects are described.

Modeling of Non-Homogeneous Containment Atmosphere in the ThAI Experimental Facility Using a CFD Code

DOE Office of Scientific and Technical Information (OSTI.GOV)

Babic, Miroslav; Kljenak, Ivo; Mavko, Borut

2006-07-01

The CFD code CFX4.4 was used to simulate an experiment in the ThAI facility, which was designed for investigation of thermal-hydraulic processes during a severe accident inside a Light Water Reactor containment. In the considered experiment, air was initially present in the vessel, and helium and steam were injected during different phases of the experiment at various mass flow rates and at different locations. The main purpose of the simulation was to reproduce the non-homogeneous temperature and species concentration distributions in the ThAI experimental facility. A three-dimensional model of the ThAI vessel for the CFX4.4 code was developed. The flowmore » in the simulation domain was modeled as single-phase. Steam condensation on vessel walls was modeled as a sink of mass and energy using a correlation that was originally developed for an integral approach. A simple model of bulk phase change was also introduced. The calculated time-dependent variables together with temperature and concentration distributions at the end of experiment phases are compared to experimental results. (authors)« less

The experience of the FERMI@Elettra photon beam transport and diagnostics system (PADReS) during three years of continuous support of machine and user experiments: achievements, lessons learned, and future upgrades

NASA Astrophysics Data System (ADS)

Zangrando, Marco; Fava, Claudio; Gerusina, Simone; Gobessi, Riccardo; Mahne, Nicola; Mazzucco, Eric; Raimondi, Lorenzo; Rumiz, Luca; Svetina, Cristian

2014-09-01

The FERMI FEL facility has begun delivering photons in 2011, becoming in late 2012 the first seeded facility open to external users worldwide. Since then, several tens of experiments have been carried out on the three operative endstations LDM, DiProI, and EIS-TIMEX. Starting from the commissioning phase, the transport and diagnostics system (PADReS) has been continuously developed and upgraded, becoming the indispensable interface between the machine and the experimental chambers. Moreover, PADReS itself has served as an active player for several machine studies as well as for various state-of-the-art experiments. In particular, some elements of PADReS have become key features to perform cutting edge experiments: the online energy spectrometer, the active optics refocusing systems, the split and delay line, and so on. For each of them the peculiar advantages will be described showing the actual implementation in the experiments. The experience gathered so far in fulfilling the needs of both machine and experimental physicists will be discussed, with particular emphasis on the solutions adopted in different scenarios. Recurrent requests and major difficulties will be reported so to give a glimpse about the standard tasks to be solved when preparing new and demanding experiments. Finally, some ideas and near-future improvements will be presented and discussed.

Alternating phase-shifted mask for logic gate levels, design, and mask manufacturing

NASA Astrophysics Data System (ADS)

Liebmann, Lars W.; Graur, Ioana C.; Leipold, William C.; Oberschmidt, James M.; O'Grady, David S.; Regaill, Denis

1999-07-01

While the benefits of alternating phase shifted masks in improving lithographic process windows at increased resolution are well known throughout the lithography community, broad implementation of this potentially powerful technique has been slow due to the inherent complexity of the layout design and mask manufacturing process. This paper will review a project undertaken at IBM's Semiconductor Research and Development Center and Mask Manufacturing and Development facility to understand the technical and logistical issues associated with the application of alternating phase shifted mask technology to the gate level of a full microprocessor chip. The work presented here depicts an important milestone toward integration of alternating phase shifted masks into the manufacturing process by demonstrating an automated design solution and yielding a functional alternating phase shifted mask. The design conversion of the microprocessor gate level to a conjugate twin shifter alternating phase shift layout was accomplished with IBM's internal design system that automatically scaled the design, added required phase regions, and resolved phase conflicts. The subsequent fabrication of a nearly defect free phase shifted mask, as verified by SEM based die to die inspection, highlights the maturity of the alternating phase shifted mask manufacturing process in IBM's internal mask facility. Well defined and recognized challenges in mask inspection and repair remain and the layout of alternating phase shifted masks present a design and data preparation overhead, but the data presented here demonstrate the feasibility of designing and building manufacturing quality alternating phase shifted masks for the gate level of a microprocessor.

Analyzing the effect of slotted foil on radiation pulse profile in a mode locked afterburner X-ray free electron laser

NASA Astrophysics Data System (ADS)

Kumar, Sandeep; Hur, Min Sup; Chung, Moses

2017-06-01

Extremely short X-ray pulses in the attosecond (as) range are important tools for ultrafast dynamics, high resolution microscopy, and nuclear dynamics study. In this paper, we numerically examine the generation of gigawatt (GW) mode-locked (ML) multichromatic X-rays using the parameters of the Pohang Accelerator Laboratory (PAL)-X-ray free electron laser (XFEL), the Korean XFEL. In this vein, we analyze the ML-FEL [Thompson and McNeil, Phys. Rev. Lett. 100, 203901 (2008)] and mode-locked afterburner (MLAB) FEL [Dunning et al., Phys. Rev. Lett. 110, 104801 (2013)] schemes on the hard X-ray beamline of the PAL-XFEL. Using the ML scheme, we numerically demonstrate a train of radiation pulses in the hard X-ray (photon energy ˜12.4 keV) with 3.5 GW power and 16 as full-width half maximum (FWHM) pulse duration. On the other hand, using the MLAB scheme, a train of radiation pulses with 3 GW power and 1 as FWHM (900 zs in RMS) pulse duration has been obtained at 12.4 keV photon energy. Both schemes generate broadband, discrete, and coherent spectrum compared to the XFEL's narrowband spectrum. Furthermore, the effect of slotted foil is also studied first time on the MLAB-FEL output. Numerical comparisons show that the temporal structure of the MLAB-FEL output can be improved significantly by the use of the slotted foil. Such short X-ray pulses at XFEL facilities will allow the studies of electron-nuclear and nuclear dynamics in atoms or molecules, and the broadband radiation will substantially improve the efficiency of the experimental techniques such as X-ray crystallography and spectroscopy, paving the way for outstanding progress in biology and material science.

40 CFR 86.1813-17 - Evaporative and refueling emission standards.

Code of Federal Regulations, 2014 CFR

2014-07-01

... vehicles, as described in § 86.1861 starting in model year 2017. You comply with the emission standard for... standards start to phase in with model year 2017 for vehicles at or below 6,000 pounds GVWR and with model... to standards under this paragraph (a) for the applicable model year; however, if all your FELs for...

Advanced photoinjector experiment photogun commissioning results

NASA Astrophysics Data System (ADS)