Bedload transport rates in a step-pool channel at near-bankfull flows

Treesearch

Daniel A. Marion

2001-01-01

This paper examines unit bedload transport rates (BTRs) at near-bankfull flows within a small step-pool channel in the Ouachita Mountains of central Arkansas. For this study, five runoff events with peak discharges between 0.25 and 1.34 cms (1.0- to 1.6-yr recurrence intervals) were produced in a natural channel using a streamflow simulation system. BTRs range from...

A stepped leader model for lightning including charge distribution in branched channels

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shi, Wei; Zhang, Li; Li, Qingmin, E-mail: lqmeee@ncepu.edu.cn

2014-09-14

The stepped leader process in negative cloud-to-ground lightning plays a vital role in lightning protection analysis. As lightning discharge usually presents significant branched or tortuous channels, the charge distribution along the branched channels and the stochastic feature of stepped leader propagation were investigated in this paper. The charge density along the leader channel and the charge in the leader tip for each lightning branch were approximated by introducing branch correlation coefficients. In combination with geometric characteristics of natural lightning discharge, a stochastic stepped leader propagation model was presented based on the fractal theory. By comparing simulation results with the statisticsmore » of natural lightning discharges, it was found that the fractal dimension of lightning trajectory in simulation was in the range of that observed in nature and the calculation results of electric field at ground level were in good agreement with the measurements of a negative flash, which shows the validity of this proposed model. Furthermore, a new equation to estimate the lightning striking distance to flat ground was suggested based on the present model. The striking distance obtained by this new equation is smaller than the value estimated by previous equations, which indicates that the traditional equations may somewhat overestimate the attractive effect of the ground.« less

KCNE1 divides the voltage sensor movement in KCNQ1/KCNE1 channels into two steps

NASA Astrophysics Data System (ADS)

Barro-Soria, Rene; Rebolledo, Santiago; Liin, Sara I.; Perez, Marta E.; Sampson, Kevin J.; Kass, Robert S.; Larsson, H. Peter

2014-04-01

The functional properties of KCNQ1 channels are highly dependent on associated KCNE-β subunits. Mutations in KCNQ1 or KCNE subunits can cause congenital channelopathies, such as deafness, cardiac arrhythmias and epilepsy. The mechanism by which KCNE1-β subunits slow the kinetics of KCNQ1 channels is a matter of current controversy. Here we show that KCNQ1/KCNE1 channel activation occurs in two steps: first, mutually independent voltage sensor movements in the four KCNQ1 subunits generate the main gating charge movement and underlie the initial delay in the activation time course of KCNQ1/KCNE1 currents. Second, a slower and concerted conformational change of all four voltage sensors and the gate, which opens the KCNQ1/KCNE1 channel. Our data show that KCNE1 divides the voltage sensor movement into two steps with widely different voltage dependences and kinetics. The two voltage sensor steps in KCNQ1/KCNE1 channels can be pharmacologically isolated and further separated by a disease-causing mutation.

Aerodynamic Impact of an Aft-Facing Slat-Step on High Re Airfoils

NASA Astrophysics Data System (ADS)

Kibble, Geoffrey; Petrin, Chris; Jacob, Jamey; Elbing, Brian; Ireland, Peter; Black, Buddy

2016-11-01

Typically, the initial aerodynamic design and subsequent testing and simulation of an aircraft wing assumes an ideal wing surface without imperfections. In reality, however the surface of an in-service aircraft wing rarely matches the surface characteristics of the test wings used during the conceptual design phase and certification process. This disconnect is usually deemed negligible or overlooked entirely. Specifically, many aircraft incorporate a leading edge slat; however, the mating between the slat and the top surface of the wing is not perfectly flush and creates a small aft-facing step behind the slat. In some cases, the slat can create a step as large as one millimeter tall, which is entirely submerged within the boundary layer. This abrupt change in geometry creates a span-wise vortex behind the step and in transonic flow causes a shock to form near the leading edge. This study investigates both experimentally and computationally the implications of an aft-facing slat-step on an aircraft wing and is compared to the ideal wing surface for subsonic and transonic flow conditions. The results of this study are useful for design of flow control modifications for aircraft currently in service and important for improving the next generation of aircraft wings.

CHANNEL EVOLUTION IN MODIFIED ALLUVIAL STREAMS.

USGS Publications Warehouse

Simon, Andrew; Hupp, Cliff R.

1987-01-01

This study (a) assesses the channel changes and network trends of bed level response after modifications between 1959 and 1972 of alluvial channels in western Tennessee and (b) develops a conceptual model of bank slope development to qualitatively assess bank stability and potential channel widening. A six-step, semiquantitative model of channel evolution in disturbed channels was developed by quantifying bed level trends and recognizing qualitative stages of bank slope development. Development of the bank profile is defined in terms of three dynamic and observable surfaces: (a) vertical face (70 to 90 degrees), (b) upper bank (25 to 50 degrees), and (c) slough line (20 to 25 degrees).

Cyclic steps and superimposed antidune deposits: important elements of coarse-grained deepwater channel-levée complexes

NASA Astrophysics Data System (ADS)

Lang, Joerg; Brandes, Christian; Winsemann, Jutta

2017-04-01

The facies distribution and architecture of submarine fans can be strongly impacted by erosion and deposition by supercritical density flows. We present field examples from the Sandino Forearc Basin (southern Central America), where cyclic-step and antidune deposits represent important sedimentary facies of coarse-grained channel-levée complexes. These bedforms occur in all sub-environments of the depositional systems and relate to the different stages of avulsion, bypass, levée construction and channel backfilling. Large-scale scours (18 to 29 m deep, 18 to 25 m wide, 60 to >120 m long) with an amalgamated infill, comprising massive, normally coarse-tail graded or spaced subhorizontally stratified conglomerates and pebbly sandstones, are interpreted as deposits of the hydraulic-jump zone of cyclic steps. These cyclic steps probably formed during avulsion, when high-density flows were routed into the evolving channel. The large-scale scour fills can be distinguished from small-scale channel fills based on the preservation of a steep upper margin and a coarse-grained infill comprising mainly amalgamated hydraulic-jump deposits. Channel fills include repetitive successions deposited by cyclic steps with superimposed antidunes. The hydraulic-jump zone of cyclic-step deposits comprises regularly spaced scours (0.2 to 2.6 m deep, 0.8 to 23 m wide), which are infilled by intraclast-rich conglomerates or pebbly sandstones and display normal coarse-tail grading or backsets. Laterally and vertically these deposits are associated with subhorizontally stratified, low-angle cross-stratified or sinusoidal stratified pebbly sandstones and sandstones (wavelength 0.5 to 18 m), interpreted as representing antidune deposits formed on the stoss-side of the cyclic steps during flow re-acceleration. The field examples indicate that so-called crudely or spaced stratified deposits may commonly represent antidune deposits with varying stratification styles controlled by the aggradation

Fine-grained bed patch response to near-bankfull flows in a step-pool channel

Treesearch

Daniel A. Marion; Frank Weirich

1999-01-01

Fine-grained bed patches were monitored in a representative step-pool channel in the Arkansas Ouachita Mountains to assess their response to near-bankfull streamflow events. These patches are small, relatively well-sorted bed areas predominantly composed of gravel-size and smaller grains. They occupy 5.2 and 4.1 percent of the active and bankfull channel areas,...

The evolution of a colluvial hollow to a fluvial channel with periodic steps following two transformational disturbances: A wildfire and a historic flood

NASA Astrophysics Data System (ADS)

Rengers, F. K.; McGuire, L. A.; Ebel, B. A.; Tucker, G. E.

2018-05-01

The transition of a colluvial hollow to a fluvial channel with discrete steps was observed after two landscape-scale disturbances. The first disturbance, a high-severity wildfire, changed the catchment hydrology to favor overland flow, which incised a colluvial hollow, creating a channel in the same location. This incised channel became armored with cobbles and boulders following repeated post-wildfire overland flow events. Three years after the fire, a record rainstorm produced regional flooding and generated sufficient fluvial erosion and sorting to produce a fluvial channel with periodically spaced steps. An analysis of the step spacing shows that after the flood, newly formed steps retained a similar spacing to the topographic roughness spacing in the original colluvial hollow (prior to channelization). This suggests that despite a distinct change in channel form roughness and bedform morphology, the endogenous roughness periodicity was conserved. Variations in sediment erodibility helped to create the emergent steps as the largest particles (>D84) remained immobile, becoming step features, and downstream soil was easily winnowed away.

The evolution of a colluvial hollow to a fluvial channel with periodic steps following two transformational disturbances: A wildfire and a historic flood

USGS Publications Warehouse

Rengers, Francis K.; McGuire, Luke; Ebel, Brian A.; Tucker, G. E.

2018-01-01

The transition of a colluvial hollow to a fluvial channel with discrete steps was observed after two landscape-scale disturbances. The first disturbance, a high-severity wildfire, changed the catchment hydrology to favor overland flow, which incised a colluvial hollow, creating a channel in the same location. This incised channel became armored with cobbles and boulders following repeated post-wildfire overland flow events. Three years after the fire, a record rainstorm produced regional flooding and generated sufficient fluvial erosion and sorting to produce a fluvial channel with periodically spaced steps. An analysis of the step spacing shows that after the flood, newly formed steps retained a similar spacing to the topographic roughness spacing in the original colluvial hollow (prior to channelization). This suggests that despite a distinct change in channel form roughness and bedform morphology, the endogenous roughness periodicity was conserved. Variations in sediment erodibility helped to create the emergent steps as the largest particles ( >D84) remained immobile, becoming step features, and downstream soil was easily winnowed away.

The action of blocking agents applied to the inner face of Ca(2+)-activated K+ channels from human erythrocytes.

PubMed

Dunn, P M

1998-09-15

The actions of clotrimazole and cetiedil, two drugs known to inhibit the Gardos channel, have been studied on single intermediate conductance calcium-activated potassium (IKCa) channels in inside out patches from human red blood cells, and compared with those of TEA and Ba2+ applied to the cytoplasmic face of the membrane. TEA produced a fast block which was observed as a reduction in the amplitude of the single channel current. This effect was weakly voltage dependent with the fraction of the membrane potential sensed by TEA at its binding site (delta) of 0.18 and a Kd at 0 mV of 20.5 mM. Ba2+ was a very potent blocker of the channel, breaking the single channel activity up into bursts, inter-spersed with silent periods lasting several seconds. The effect of Ba2+ was very voltage sensitive, delta = 0.44, and a Kd at 0 mV of 0.15 microM. Clotrimazole applied to the inner face of the membrane at a concentration < or = 1 microM produced a slow block resulting in bursts of channel activity separated by quiescent periods lasting many seconds. The effect of clotrimazole was mimicked by a quaternary derivative UCL 1559, in keeping with an action at the cytoplasmic face of the channel. A high concentration of cetiedil (100 microM) produced only a weak block of the channel. The kinetics of this action were very slow, with burst and inter-burst intervals lasting several minutes. While inhibition of the Gardos channel by cetiedil is unlikely to involve an intracellular site of action, if clotrimazole is able to penetrate the membrane, part of its effect may result from binding to an intracellular site on the channel.

Optofluidic refractive-index sensor in step-index fiber with parallel hollow micro-channel.

PubMed

Lee, H W; Schmidt, M A; Uebel, P; Tyagi, H; Joly, N Y; Scharrer, M; Russell, P St J

2011-04-25

We present a simple refractive index sensor based on a step-index fiber with a hollow micro-channel running parallel to its core. This channel becomes waveguiding when filled with a liquid of index greater than silica, causing sharp dips to appear in the transmission spectrum at wavelengths where the glass-core mode phase-matches to a mode of the liquid-core. The sensitivity of the dip-wavelengths to changes in liquid refractive index is quantified and the results used to study the dynamic flow characteristics of fluids in narrow channels. Potential applications of this fiber microstructure include measuring the optical properties of liquids, refractive index sensing, biophotonics and studies of fluid dynamics on the nanoscale.

Co-evolving Physical and Biological Organization in Step-pool Channels: Experiments from a Restoration Reach on Wildcat Creek, California

NASA Astrophysics Data System (ADS)

Chin, A.; O'Dowd, A. P.; Mendez, P. K.; Velasco, K. Z.; Leventhal, R. D.; Storesund, R.; Laurencio, L. R.

2014-12-01

Step-pools are important features in fluvial systems. Through energy dissipation, step-pools provide stability in high-energy environments that otherwise may erode and degrade. Although research has focused on geomorphological aspects of step-pool channels, the ecological significance of step-pool streams is increasingly recognized. Step-pool streams often contain higher density and diversity of benthic macroinvertebrates and are critical habitats for organisms such as salmonids and tailed frogs. Step-pools are therefore increasingly used to restore eroding channels and improve ecological conditions. This paper addresses a restoration reach of Wildcat Creek in Berkeley, California that featured an installation of step-pools in 2012. The design framework recognized step-pool formation as a self-organizing process that produces a rhythmic morphology. After placing step particles at locations where step-pools are expected to form according to hydraulic theory, the self-organizing approach allowed fluvial processes to refine the rocks into adjusted sequences over time. In addition, a 30-meter "experimental" reach was created to explore the co-evolution of geomorphological and ecological characteristics. After constructing a plane bed channel, boulders and cobbles piled at the upstream end allowed natural flows to mobilize and sort them into step-pool sequences. Ground surveys and LiDAR recorded the development of step-pool sequences over several seasons. Concurrent sampling of benthic macroinvertebrates documented the formation of biological communities in conjunction with habitat. Biological sampling in an upstream reference reach provided a comparison with the restored reach over time. Results to date show an emergent step-pool channel with steps that segment the plane bed into initial step and pool habitats. Biological communities are beginning to form, showing more distinction among habitat types during some seasons, although they do not yet approach reference

Wash-away of contaminant downstream of a backward-facing step over a range of Schmidt number

NASA Astrophysics Data System (ADS)

Min, Hannah; Fischer, Paul F.; Pearlstein, Arne J.

2017-11-01

We report computations of two-dimensional unsteady convective mass transfer in flow over a backward-facing step, in which a contaminant initially present downstream of the step is ``washed away''. Results are presented for a range of Schmidt numbers, showing how the recirculation region downstream of the step not only serves to retain contaminant near the step, but also transports contaminant upstream towards the step. The results for the highest Schmidt number considered (2650) are relevant to wash-away of low-molecular weight species in liquids, for which some implications are discussed.

Variation of nanopore diameter along porous anodic alumina channels by multi-step anodization.

PubMed

Lee, Kwang Hong; Lim, Xin Yuan; Wai, Kah Wing; Romanato, Filippo; Wong, Chee Cheong

2011-02-01

In order to form tapered nanocapillaries, we investigated a method to vary the nanopore diameter along the porous anodic alumina (PAA) channels using multi-step anodization. By anodizing the aluminum in either single acid (H3PO4) or multi-acid (H2SO4, oxalic acid and H3PO4) with increasing or decreasing voltage, the diameter of the nanopore along the PAA channel can be varied systematically corresponding to the applied voltages. The pore size along the channel can be enlarged or shrunken in the range of 20 nm to 200 nm. Structural engineering of the template along the film growth direction can be achieved by deliberately designing a suitable voltage and electrolyte together with anodization time.

Stability of spanwise-modulated flows behind backward-facing steps

NASA Astrophysics Data System (ADS)

Boiko, A. V.; Dovgal, A. V.; Sorokin, A. M.

2017-10-01

An overview and synthesis of researches on development of local vortical disturbances in laminar separated flows downstream of backward-facing steps, in which the velocity field depends essentially on two variables are given. Peculiarities of transition to turbulence in such spatially inhomogeneous separated zones are discussed. The experimental data are supplemented by the linear stability characteristics of model velocity profiles of the separated flow computed using both the classical local formulation and the nonlocal approach based on the Floquet theory for partial differential equations with periodic coefficients. The results clarify the response of the local separated flows to their modulation with stationary geometrical and temperature inhomogeneities. The results can be useful for the development of new methods of laminar separation control.

Flow resistance dynamics in step-pool channels: 2. Partitioning between grain, spill, and woody debris resistance

NASA Astrophysics Data System (ADS)

Wilcox, Andrew C.; Nelson, Jonathan M.; Wohl, Ellen E.

2006-05-01

In step-pool stream channels, flow resistance is created primarily by bed sediments, spill over step-pool bed forms, and large woody debris (LWD). In order to measure resistance partitioning between grains, steps, and LWD in step-pool channels we completed laboratory flume runs in which total resistance was measured with and without grains and steps, with various LWD configurations, and at multiple slopes and discharges. Tests of additive approaches to resistance partitioning found that partitioning estimates are highly sensitive to the order in which components are calculated and that such approaches inflate the values of difficult-to-measure components that are calculated by subtraction from measured components. This effect is especially significant where interactions between roughness features create synergistic increases in resistance such that total resistance measured for combinations of resistance components greatly exceeds the sum of those components measured separately. LWD contributes large proportions of total resistance by creating form drag on individual pieces and by increasing the spill resistance effect of steps. The combined effect of LWD and spill over steps was found to dominate total resistance, whereas grain roughness on step treads was a small component of total resistance. The relative contributions of grain, spill, and woody debris resistance were strongly influenced by discharge and to a lesser extent by LWD density. Grain resistance values based on published formulas and debris resistance values calculated using a cylinder drag approach typically underestimated analogous flume-derived values, further illustrating sources of error in partitioning methods and the importance of accounting for interaction effects between resistance components.

Three-step Channel Conformational Changes Common to DNA Packaging Motors of Bacterial Viruses T3, T4, SPP1, and Phi29

PubMed Central

Wang, Shaoying; Ji, Zhouxiang; Yan, Erfu; Haque, Farzin; Guo, Peixuan

2016-01-01

The DNA packaging motor of dsDNA bacterial viruses contains a head-tail connector with a channel for genome to enter during assembly and to exit during host infection. The DNA packaging motor of bacterial virus phi29 was recently reported to use the “One-way Revolution” mechanism for DNA packaging. This raises a question of how dsDNA is ejected during infection if the channel acts as a one-way inward valve. Here we report a three step conformational change of the portal channel that is common among DNA translocation motors of bacterial viruses T3, T4, SPP1, and phi29. The channels of these motors exercise three discrete steps of gating, as revealed by electrophysiological assays. It is proposed that the three step channel conformational changes occur during DNA entry process, resulting in a structural transition in preparation of DNA movement in the reverse direction during ejection. PMID:27181501

Two-step superresolution approach for surveillance face image through radial basis function-partial least squares regression and locality-induced sparse representation

NASA Astrophysics Data System (ADS)

Jiang, Junjun; Hu, Ruimin; Han, Zhen; Wang, Zhongyuan; Chen, Jun

2013-10-01

Face superresolution (SR), or face hallucination, refers to the technique of generating a high-resolution (HR) face image from a low-resolution (LR) one with the help of a set of training examples. It aims at transcending the limitations of electronic imaging systems. Applications of face SR include video surveillance, in which the individual of interest is often far from cameras. A two-step method is proposed to infer a high-quality and HR face image from a low-quality and LR observation. First, we establish the nonlinear relationship between LR face images and HR ones, according to radial basis function and partial least squares (RBF-PLS) regression, to transform the LR face into the global face space. Then, a locality-induced sparse representation (LiSR) approach is presented to enhance the local facial details once all the global faces for each LR training face are constructed. A comparison of some state-of-the-art SR methods shows the superiority of the proposed two-step approach, RBF-PLS global face regression followed by LiSR-based local patch reconstruction. Experiments also demonstrate the effectiveness under both simulation conditions and some real conditions.

The Effect of Backward-Facing Step Height on Instability Growth and Breakdown in Swept Wing Boundary-Layer Transition

NASA Technical Reports Server (NTRS)

Eppink, Jenna L.; Wlezien, Richard W.; King, Rudolph A.; Choudhari, Meelan

2015-01-01

A low-speed experiment was performed on a swept at plate model with an imposed pressure gradient to determine the effect of a backward-facing step on transition in a stationary-cross flow dominated flow. Detailed hot-wire boundary-layer measurements were performed for three backward-facing step heights of approximately 36, 45, and 49% of the boundary-layer thickness at the step. These step heights correspond to a subcritical, nearly-critical, and critical case. Three leading-edge roughness configurations were tested to determine the effect of stationary-cross flow amplitude on transition. The step caused a local increase in amplitude of the stationary cross flow for the two larger step height cases, but farther downstream the amplitude decreased and remained below the baseline amplitude. The smallest step caused a slight local decrease in amplitude of the primary stationary cross flow mode, but the amplitude collapsed back to the baseline case far downstream of the step. The effect of the step on the amplitude of the primary cross flow mode increased with step height, however, the stationary cross flow amplitudes remained low and thus, stationary cross flow was not solely responsible for transition. Unsteady disturbances were present downstream of the step for all three step heights, and the amplitudes increased with increasing step height. The only exception is that the lower frequency (traveling crossflow-like) disturbance was not present in the lowest step height case. Positive and negative spikes in instantaneous velocity began to occur for the two larger step height cases and then grew in number and amplitude downstream of reattachment, eventually leading to transition. The number and amplitude of spikes varied depending on the step height and cross flow amplitude. Despite the low amplitude of the disturbances in the intermediate step height case, breakdown began to occur intermittently and the flow underwent a long transition region.

Least-squares finite element solutions for three-dimensional backward-facing step flow

NASA Technical Reports Server (NTRS)

Jiang, Bo-Nan; Hou, Lin-Jun; Lin, Tsung-Liang

1993-01-01

Comprehensive numerical solutions of the steady state incompressible viscous flow over a three-dimensional backward-facing step up to Re equals 800 are presented. The results are obtained by the least-squares finite element method (LSFEM) which is based on the velocity-pressure-vorticity formulation. The computed model is of the same size as that of Armaly's experiment. Three-dimensional phenomena are observed even at low Reynolds number. The calculated values of the primary reattachment length are in good agreement with experimental results.

Hot Film Velocity Measurements Downstream of a Swept Backward-Facing Step

DTIC Science & Technology

1990-08-01

WR ~4’ nol w of tdl. O64" $l"uwe. suite 424 i lV~lZdO . 00 to effice at UAqeww0fl" S4 aud ’mpeom t, 0edUOM ’l~c 004 S~ a lleq~k Dc 2010). I. AGENCY USE ...Velocity measurements were made using a single component hot film anemometer. Results from this study indicate the following: the flow in the recirculation...velocity component parallel to the step face retains a finite magnitude. Coles’ law of the wall and wake was used to corralate the data from this study. The

Stepped care versus face-to-face cognitive behavior therapy for panic disorder and social anxiety disorder: Predictors and moderators of outcome.

PubMed

Haug, Thomas; Nordgreen, Tine; Öst, Lars-Göran; Kvale, Gerd; Tangen, Tone; Andersson, Gerhard; Carlbring, Per; Heiervang, Einar R; Havik, Odd E

2015-08-01

To investigate predictors and moderators of treatment outcome by comparing immediate face-to-face cognitive behavioral therapy (FtF-CBT) to a Stepped Care treatment model comprising three steps: Psychoeducation, Internet-delivered CBT, and FtF-CBT for panic disorder (PD) and social anxiety disorder (SAD). Patients (N = 173) were recruited from nine public mental health out-patient clinics and randomized to immediate FtF-CBT or Stepped Care treatment. Characteristics related to social functioning, impairment from the anxiety disorder, and comorbidity was investigated as predictors and moderators by treatment format and diagnosis in multiple regression analyses. Lower social functioning, higher impairment from the anxiety disorder, and a comorbid cluster C personality disorder were associated with significantly less improvement, particularly among patients with PD. Furthermore, having a comorbid anxiety disorder was associated with a better treatment outcome among patients with PD but not patients with SAD. Patients with a comorbid depression had similar outcomes from the different treatments, but patients without comorbid depression had better outcomes from immediate FtF-CBT compared to guided self-help. In general, the same patient characteristics appear to be associated with the treatment outcome for CBT provided in low- and high-intensity formats when treated in public mental health care clinics. The findings suggest that patients with lower social functioning and higher impairment from their anxiety disorder benefit less from these treatments and may require more adapted and extensive treatment. CLINICALTRIALS.GOV: Identifier: NCT00619138. Copyright © 2015 Elsevier Ltd. All rights reserved.

Single step sequential polydimethylsiloxane wet etching to fabricate a microfluidic channel with various cross-sectional geometries

NASA Astrophysics Data System (ADS)

Wang, C.-K.; Liao, W.-H.; Wu, H.-M.; Lo, Y.-H.; Lin, T.-R.; Tung, Y.-C.

2017-11-01

Polydimethylsiloxane (PDMS) has become a widely used material to construct microfluidic devices for various biomedical and chemical applications due to its desirable material properties and manufacturability. PDMS microfluidic devices are usually fabricated using soft lithography replica molding methods with master molds made of photolithogrpahy patterned photoresist layers on silicon wafers. The fabricated microfluidic channels often have rectangular cross-sectional geometries with single or multiple heights. In this paper, we develop a single step sequential PDMS wet etching process that can be used to fabricate microfluidic channels with various cross-sectional geometries from single-layer PDMS microfluidic channels. The cross-sections of the fabricated channel can be non-rectangular, and varied along the flow direction. Furthermore, the fabricated cross-sectional geometries can be numerically simulated beforehand. In the experiments, we fabricate microfluidic channels with various cross-sectional geometries using the developed technique. In addition, we fabricate a microfluidic mixer with alternative mirrored cross-sectional geometries along the flow direction to demonstrate the practical usage of the developed technique.

On the supersonic three-dimensional flow over an axisymmetric body with a forward-facing annular step

NASA Astrophysics Data System (ADS)

Simonenko, Mikhail; Zubkov, Alexander; Kuzmin, Alexander

2018-05-01

The 3D turbulent supersonic flow over a body of revolution at various angles of attack α is studied numerically and experimentally. The body surface incorporates a forward-facing step near its midpart and a nose cone. Experiments were conducted in a wind tunnel of the Research Institute of Mechanics, Moscow State University, at the Mach number of 3 for various lengths L of the distance between the step and nose cone. Numerical simulations were performed with a finite-volume solver ANSYS CFX-15. The study reveals bands of α and L in which the pressure on the leeward side of step abruptly increases and exceeds the pressure on the windward side.

POD analysis of flow over a backward-facing step forced by right-angle-shaped plasma actuator.

PubMed

Wang, Bin; Li, Huaxing

2016-01-01

This study aims to present flow control over the backward-facing step with specially designed right-angle-shaped plasma actuator and analyzed the influence of various scales of flow structures on the Reynolds stress through snapshot proper orthogonal decomposition (POD). 2D particle image velocimetry measurements were conducted on region (x/h = 0-2.25) and reattachment zone in the x-y plane over the backward-facing step at a Reynolds number of Re h  = 27,766 (based on step height [Formula: see text] and free stream velocity [Formula: see text]. The separated shear layer was excited by specially designed right-angle-shaped plasma actuator under the normalized excitation frequency St h  ≈ 0.345 along the 45° direction. The spatial distribution of each Reynolds stress component was reconstructed using an increasing number of POD modes. The POD analysis indicated that the flow dynamic downstream of the step was dominated by large-scale flow structures, which contributed to streamwise Reynolds stress and Reynolds shear stress. The intense Reynolds stress localized to a narrow strip within the shear layer was mainly affected by small-scale flow structures, which were responsible for the recovery of the Reynolds stress peak. With plasma excitation, a significant increase was obtained in the vertical Reynolds stress peak. Under the dimensionless frequencies St h  ≈ 0.345 and [Formula: see text] which are based on the step height and momentum thickness, the effectiveness of the flow control forced by the plasma actuator along the 45° direction was ordinary. Only the vertical Reynolds stress was significantly affected.

Phenomenological study of subsonic turbulent flow over a swept rearward-facing step. Ph.D. Thesis

NASA Technical Reports Server (NTRS)

Selby, G. V.

1982-01-01

The phenomenology of turbulent, subsonic flow over a swept, rearward-facing step was studied. Effects of variations in step height, sweep angle, base geometry, and end conditions on the 3-D separated flow were examined. The separated flow was visualized using smoke wire, oil drop, and surface tuft techniques. Measurements include surface pressure, reattachment distance and swirl angle. Results indicate: (1) model/test section coupling affects the structure of the separated flow, but spanwise end conditions do not; (2) the independence principle is evidently valid for sweep angles up to 38 deg; (3) a sweep angle/swirl angle correlation exists; and (4) base modifications can significantly reduce the reattachment distance.

Film thickness measurement for spiral groove and Rayleigh step lift pad self-acting face seals

NASA Technical Reports Server (NTRS)

Dirusso, E.

1982-01-01

One Rayleigh step lift pad and three spiral groove self-acting face seal configurations were tested to measure film thickness and frictional torque as a function of shaft speed. The seals were tested at a constant face load of 73 N (16.4 lb) with ambient air at room temperature and atmospheric pressure as the fluid medium. The test speed range was from 7000 to 17,000 rpm. The measured film thickness was compared with theoretical data from mathematical models. The mathematical models overpredicted the measured film thickness at the lower speeds of the test speed range and underpredicted the measured film thickness at the higher speeds of the test speed range.

Equal-mobility bed load transport in a small, step-pool channel in the Ouachita Mountains

Treesearch

Daniel A. Marion; Frank Weirich

2003-01-01

Abstract: Equal-mobility transport (EMT) of bed load is more evident than size-selective transport during near-bankfull flow events in a small, step-pool channel in the Ouachita Mountains of central Arkansas. Bed load transport modes were studied by simulating five separate runoff events with peak discharges between 0.25 and 1.34 m3...

A numerical solution of the supersonic flow over a rearward facing step with transverse non-reacting hydrogen injection

NASA Technical Reports Server (NTRS)

Berman, H. A.; Anderson, J. D., Jr.; Drummond, J. P.

1982-01-01

The present investigation represents an application of computational fluid dynamics to a problem associated with the flow in the combustor region of a supersonic combustion ramjet engine (scramjet). The governing equations are considered, taking into account the Navier-Stokes equations, a molecular viscosity calculation, the molecular thermal conductivity, molecular diffusion, and a turbulence model. The employed numerical solution is patterned after the explicit, time-dependent, unsplit, predictor-corrector, finite-difference method given by MacCormack (1969). The calculation is concerned with the supersonic flow over a rearward-facing step with transverse H2 injection at conditions germane to the combustor region of a scramjet engine. The H2 jet acts as an effective body which essentially shields the primary flow from the rearward-facing step, thus substantially changing the wave pattern in the primary flow.

Computation of turbulent flows over backward and forward-facing steps using a near-wall Reynolds stress model

NASA Technical Reports Server (NTRS)

Ko, Sung HO

1993-01-01

Separation and reattachment of turbulent shear layers is observed in many important engineering applications, yet it is poorly understood. This has motivated many studies on understanding and predicting the processes of separation and reattachment of turbulent shear layers. Both of the situations in which separation is induced by adverse pressure gradient, or by discontinuities of geometry, have attracted attention of turbulence model developers. Formulation of turbulence closure models to describe the essential features of separated turbulent flows accurately is still a formidable task. Computations of separated flows associated with sharp-edged bluff bodies are described. For the past two decades, the backward-facing step flow, the simplest separated flow, has been a popular test case for turbulence models. Detailed studies on the performance of many turbulence models, including two equation turbulence models and Reynolds stress models, for flows over steps can be found in the papers by Thangam & Speziale and Lasher & Taulbee). These studies indicate that almost all the existing turbulence models fail to accurately predict many important features of back step flow such as reattachment length, recovery rate of the redeveloping boundary layers downstream of the reattachment point, streamlines near the reattachment point, and the skin friction coefficient. The main objectives are to calculate flows over backward and forward-facing steps using the NRSM and to make use of the newest DNS data for detailed comparison. This will give insights for possible improvements of the turbulence model.

Dynamic Behavior of Spiral-Groove and Rayleigh-Step Self-Acting Face Seals

NASA Technical Reports Server (NTRS)

Dirusso, Eliseo

1984-01-01

Tests were performed to determine the dynamic behavior and establish baseline dynamic data for five self-acting face seals employing Rayleigh-step lift-pads and inward pumping as well as outward-pumping spiral grooves for the lift-generating mechanism. The primary parameters measured in the tests were film thickness, seal seat axial motion, and seal frictional torque. The data show the dynamic response of the film thickness to the motion of the seal seat. The inward-pumping spiral-groove seals exhibited a high-amplitude film thickness vibratory mode with a frequency of four times the shaft speed. This mode was not observed in the other seals tested. The tests also revealed that high film thickness vibration amplitude produces considerably higher average film thickness than do low amplitude film thickness vibrations. The seals were tested at a constant face load of 73 N (16.4 lb) with ambient air at room temperature and atmospheric pressure as the fluid medium. The test speed range was from 7000 to 17000 rpm. Seal tangential speed range was 34.5 to 83.7 m/sec (113 to 274 ft/sec).

Hybrid mesh finite volume CFD code for studying heat transfer in a forward-facing step

NASA Astrophysics Data System (ADS)

Jayakumar, J. S.; Kumar, Inder; Eswaran, V.

2010-12-01

Computational fluid dynamics (CFD) methods employ two types of grid: structured and unstructured. Developing the solver and data structures for a finite-volume solver is easier than for unstructured grids. But real-life problems are too complicated to be fitted flexibly by structured grids. Therefore, unstructured grids are widely used for solving real-life problems. However, using only one type of unstructured element consumes a lot of computational time because the number of elements cannot be controlled. Hence, a hybrid grid that contains mixed elements, such as the use of hexahedral elements along with tetrahedral and pyramidal elements, gives the user control over the number of elements in the domain, and thus only the domain that requires a finer grid is meshed finer and not the entire domain. This work aims to develop such a finite-volume hybrid grid solver capable of handling turbulence flows and conjugate heat transfer. It has been extended to solving flow involving separation and subsequent reattachment occurring due to sudden expansion or contraction. A significant effect of mixing high- and low-enthalpy fluid occurs in the reattached regions of these devices. This makes the study of the backward-facing and forward-facing step with heat transfer an important field of research. The problem of the forward-facing step with conjugate heat transfer was taken up and solved for turbulence flow using a two-equation model of k-ω. The variation in the flow profile and heat transfer behavior has been studied with the variation in Re and solid to fluid thermal conductivity ratios. The results for the variation in local Nusselt number, interface temperature and skin friction factor are presented.

Numerical simulations of three-dimensional laminar flow over a backward facing step; flow near side walls

NASA Technical Reports Server (NTRS)

Steinthorsson, Erlendur; Liou, Meng-Sing; Povinelli, Louis A.; Arnone, Andrea

1993-01-01

This paper reports the results of numerical simulations of steady, laminar flow over a backward-facing step. The governing equations used in the simulations are the full 'compressible' Navier-Stokes equations, solutions to which were computed by using a cell-centered, finite volume discretization. The convection terms of the governing equations were discretized by using the Advection Upwind Splitting Method (AUSM), whereas the diffusion terms were discretized using central differencing formulas. The validity and accuracy of the numerical solutions were verified by comparing the results to existing experimental data for flow at identical Reynolds numbers in the same back step geometry. The paper focuses attention on the details of the flow field near the side wall of the geometry.

Experimental study of combustion in a turbulent free shear layer formed at a rearward facing step

NASA Technical Reports Server (NTRS)

Pitz, R. W.; Daily, J. W.

1981-01-01

A premixed propane-air flame is stabilized in a turbulent free shear layer formed at a rearward facing step. The mean and rms averages of the turbulent velocity flow field are determined by LDV for both reacting (equivalence ratio 0.57) and nonreacting flows (Reynolds number 15,000-37,000 based on step height). The effect of combustion is to shift the layer toward the recirculation zone and reduce the flame spread. For reacting flow, the growth rate is unchanged except very near the step. The probability density function of the velocity is bimodial near the origin of the reacting layer and single-peaked but often skewed elsewhere. Large-scale structures dominate the reacting shear layer. Measurements of their passing frequency from LDV are consistent with high-speed Schlieren movies of the reacting layer and indicate that the coalescence rate of the eddies in the shear layer is reduced by combustion.

Two-Step Fair Scheduling of Continuous Media Streams over Error-Prone Wireless Channels

NASA Astrophysics Data System (ADS)

Oh, Soohyun; Lee, Jin Wook; Park, Taejoon; Jo, Tae-Chang

In wireless cellular networks, streaming of continuous media (with strict QoS requirements) over wireless links is challenging due to their inherent unreliability characterized by location-dependent, bursty errors. To address this challenge, we present a two-step scheduling algorithm for a base station to provide streaming of continuous media to wireless clients over the error-prone wireless links. The proposed algorithm is capable of minimizing the packet loss rate of individual clients in the presence of error bursts, by transmitting packets in the round-robin manner and also adopting a mechanism for channel prediction and swapping.

Two-step rating-based 'double-faced applicability' test for sensory analysis of spread products as an alternative to descriptive analysis with trained panel.

PubMed

Kim, In-Ah; den-Hollander, Elyn; Lee, Hye-Seong

2018-03-01

Descriptive analysis with a trained sensory panel has thus far been the most well defined methodology to characterize various products. However, in practical terms, intensive training in descriptive analysis has been recognized as a serious defect. To overcome this limitation, various novel rapid sensory profiling methodologies have been suggested in the literature. Among these, attribute-based methodologies such as check-all-that-apply (CATA) questions showed results comparable to those of conventional sensory descriptive analysis. Kim, Hopkinson, van Hout, and Lee (2017a, 2017b) have proposed a novel attribute-based methodology termed the two-step rating-based 'double-faced applicability' test with a novel output measure of applicability magnitude (d' A ) for measuring consumers' product usage experience throughout various product usage stages. In this paper, the potential of the two-step rating-based 'double-faced applicability' test with d' A was investigated as an alternative to conventional sensory descriptive analysis in terms of sensory characterization and product discrimination. Twelve commercial spread products were evaluated using both conventional sensory descriptive analysis with a trained sensory panel and two-step rating-based 'double-faced applicability' test with an untrained sensory panel. The results demonstrated that the 'double-faced applicability' test can be used to provide a direct measure of the applicability magnitude of sensory attributes of the samples tested in terms of d' A for sensory characterization of individual samples and multiple sample comparisons. This suggests that when the appropriate list of attributes to be used in the questionnaire is already available, the two-step rating-based 'double-faced applicability' test with d' A can be used as a more efficient alternative to conventional descriptive analysis, without requiring any intensive training process. Copyright © 2017 Elsevier Ltd. All rights reserved.

A Power-Efficient Clustering Protocol for Coal Mine Face Monitoring with Wireless Sensor Networks Under Channel Fading Conditions

PubMed Central

Ren, Peng; Qian, Jiansheng

2016-01-01

This study proposes a novel power-efficient and anti-fading clustering based on a cross-layer that is specific to the time-varying fading characteristics of channels in the monitoring of coal mine faces with wireless sensor networks. The number of active sensor nodes and a sliding window are set up such that the optimal number of cluster heads (CHs) is selected in each round. Based on a stable expected number of CHs, we explore the channel efficiency between nodes and the base station by using a probe frame and the joint surplus energy in assessing the CH selection. Moreover, the sending power of a node in different periods is regulated by the signal fade margin method. The simulation results demonstrate that compared with several common algorithms, the power-efficient and fading-aware clustering with a cross-layer (PEAFC-CL) protocol features a stable network topology and adaptability under signal time-varying fading, which effectively prolongs the lifetime of the network and reduces network packet loss, thus making it more applicable to the complex and variable environment characteristic of a coal mine face. PMID:27338380

Stereo Particle Image Velocimetry Measurements of Transition Downstream of a Backward-Facing Step in a Swept-Wing Boundary Layer

NASA Technical Reports Server (NTRS)

Eppink, Jenna L.; Yao, Chung-Sheng

2017-01-01

Stereo particle image velocimetry measurements were performed downstream of a backward-facing step in a stationary-cross flow dominated flow. The PIV measurements exhibit excellent quantitative and qualitative agreement with the previously acquired hotwire data. Instantaneous PIV snapshots reveal new information about the nature and cause of the \\spikes" that occurred prior to breakdown in both the hotwire and PIV data. The PIV snapshots show that the events occur simultaneously across multiple stationary cross flow wavelengths, indicating that this is not simply a local event, but is likely caused by the 2D Tollmien-Schlichting instability that is introduced by the step. While the TS instability is a 2D instability, it is also modulated in the spanwise direction due to interactions with the stationary cross flow, as are the other unsteady disturbances present. Because of this modulation, the "spike" events cause an instantaneous increase of the spanwise modulation of the streamwise and spanwise velocity initially caused by the stationary cross flow. Breakdown appears to be caused by this instantaneous modulation, possibly due to a high-frequency secondary instability similar to a traveling-cross flow breakdown scenario. These results further illuminate the respective roles of the stationary cross flow and unsteady disturbances in transition downstream of a backward-facing step.

A comparative study of computational solutions to flow over a backward-facing step

NASA Technical Reports Server (NTRS)

Mizukami, M.; Georgiadis, N. J.; Cannon, M. R.

1993-01-01

A comparative study was conducted for computational fluid dynamic solutions to flow over a backward-facing step. This flow is a benchmark problem, with a simple geometry, but involves complicated flow physics such as free shear layers, reattaching flow, recirculation, and high turbulence intensities. Three Reynolds-averaged Navier-Stokes flow solvers with k-epsilon turbulence models were used, each using a different solution algorithm: finite difference, finite element, and hybrid finite element - finite difference. Comparisons were made with existing experimental data. Results showed that velocity profiles and reattachment lengths were predicted reasonably well by all three methods, while the skin friction coefficients were more difficult to predict accurately. It was noted that, in general, selecting an appropriate solver for each problem to be considered is important.

Transverse injection into Mach 2 flow behind a rearward-facing step - A 3-D, compressible flow test case for hypersonic combustor CFD validation

NASA Technical Reports Server (NTRS)

Mcdaniel, James C.; Fletcher, Douglas G.; Hartfield, Roy J.; Hollo, Steven D.

1991-01-01

A spatially-complete data set of the important primitive flow variables is presented for the complex, nonreacting, 3D unit combustor flow field employing transverse injection into a Mach 2 flow behind a rearward-facing step. A unique wind tunnel facility providing the capability for iodine seeding was built specifically for these measurements. Two optical techniques based on laser-induced-iodine fluorescence were developed and utilized for nonintrusive, in situ flow field measurements. LDA provided both mean and fluctuating velocity component measurements. A thermographic phosphor wall temperature measurement technique was developed and employed. Data from the 2D flow over a rearward-facing step and the complex 3D mixing flow with injection are reported.

Passive control of coherent structures in a modified backwards-facing step flow

NASA Astrophysics Data System (ADS)

Ormonde, Pedro C.; Cavalieri, André V. G.; Silva, Roberto G. A. da; Avelar, Ana C.

2018-05-01

We study a modified backwards-facing step flow, with the addition of two different plates; one is a baseline, impermeable plate and the second a perforated one. An experimental investigation is carried out for a turbulent reattaching shear layer downstream of the two plates. The proposed setup is a model configuration to study how the plate characteristics affect the separated shear layer and how turbulent kinetic energies and large-scale coherent structures are modified. Measurements show that the perforated plate changes the mean flow field, mostly by reducing the intensity of reverse flow close to the bottom wall. Disturbance amplitudes are significantly reduced up to five step heights downstream of the trailing edge of the plate, more specifically in the recirculation region. A loudspeaker is then used to introduce phase-locked, low-amplitude perturbations upstream of the plates, and phase-averaged measurements allow a quantitative study of large-scale structures in the shear-layer. The evolution of such coherent structures is evaluated in light of linear stability theory, comparing the eigenfunction of the Kelvin-Helmholtz mode to the experimental results. We observe a close match of linear-stability eigenfunctions with phase-averaged amplitudes for the two tested Strouhal numbers. The perforated plate is found to reduce the amplitude of the Kelvin-Helmholtz coherent structures in comparison to the baseline, impermeable plate, a behavior consistent with the predicted amplification trends from linear stability.

Applicability of the independence principle to subsonic turbulent flow over a swept rearward-facing step

NASA Technical Reports Server (NTRS)

Selby, G. V.

1983-01-01

Prandtl (1946) has concluded that for yawed laminar incompressible flows the streamwise flow is independent of the spanwise flow. However, Ashkenas and Riddell (1955) have reported that for turbulent flow the 'independence principle' does not apply to yawed flat plates. On the other hand, it was also found that this principle may be applicable to many turbulent flows. As the sweep angle is increased, a sweep angle is reached which defines the interval over which the 'independence principle' is valid. The results obtained in the present investigation indicate the magnitude of the critical angle for subsonic turbulent flow over a swept rearward-facing step.

Stereo Particle Image Velocimetry Measurements of Transition Downstream of a Forward-Facing Step in a Swept-Wing Boundary Layer

NASA Technical Reports Server (NTRS)

Eppink, Jenna L.

2017-01-01

Stereo particle image velocimetry measurements were performed downstream of a forward-facing step in a stationary-crossflow dominated flow. Three different step heights were studied with the same leading-edge roughness configuration to determine the effect of the step on the evolution of the stationary-crossflow. Above the critical step height, which is approximately 68% of the boundary-layer thickness at the step, the step caused a significant increase in the growth of the stationary crossflow. For the largest step height studied (68%), premature transition occurred shortly downstream of the step. The stationary crossflow amplitude only reached approximately 7% of U(sub e) in this case, which suggests that transition does not occur via the high-frequency secondary instabilities typically associated with stationary crossflow transition. The next largest step of 60% delta still caused a significant impact on the growth of the stationary crossflow downstream of the step, but the amplitude eventually returned to that of the baseline case, and the transition front remained the same. The smallest step height (56%) only caused a small increase in the stationary crossflow amplitude and no change in the transition front. A final case was studied in which the roughness on the leading edge of the model was enhanced for the lowest step height case to determine the impact of the stationary crossflow amplitude on transition. The stationary crossflow amplitude was increased by approximately four times, which resulted in premature transition for this step height. However, some notable differences were observed in the behavior of the stationary crossflow mode, which indicate that the interaction mechanism which results in the increased growth of the stationary crossflow downstream of the step may be different in this case compared to the larger step heights.

Flow control of micro-ramps on supersonic forward-facing step flow

NASA Astrophysics Data System (ADS)

Qing-Hu, Zhang; Tao, Zhu; Shihe, Yi; Anping, Wu

2016-05-01

The effects of the micro-ramps on supersonic turbulent flow over a forward-facing step (FFS) was experimentally investigated in a supersonic low-noise wind tunnel at Mach number 3 using nano-tracer planar laser scattering (NPLS) and particle image velocimetry (PIV) techniques. High spatiotemporal resolution images and velocity fields of supersonic flow over the testing model were captured. The fine structures and their spatial evolutionary characteristics without and with the micro-ramps were revealed and compared. The large-scale structures generated by the micro-ramps can survive the downstream FFS flowfield. The micro-ramps control on the flow separation and the separation shock unsteadiness was investigated by PIV results. With the micro-ramps, the reduction in the range of the reversal flow zone in streamwise direction is 50% and the turbulence intensity is also reduced. Moreover, the reduction in the average separated region and in separation shock unsteadiness are 47% and 26%, respectively. The results indicate that the micro-ramps are effective in reducing the flow separation and the separation shock unsteadiness. Project supported by the National Natural Science Foundation of China (Grant Nos. 11172326 and 11502280).

A critical comparison of several low Reynolds number k-epsilon turbulence models for flow over a backward facing step

NASA Technical Reports Server (NTRS)

Steffen, C. J., Jr.

1993-01-01

Turbulent backward-facing step flow was examined using four low turbulent Reynolds number k-epsilon models and one standard high Reynolds number technique. A tunnel configuration of 1:9 (step height: exit tunnel height) was used. The models tested include: the original Jones and Launder; Chien; Launder and Sharma; and the recent Shih and Lumley formulation. The experimental reference of Driver and Seegmiller was used to make detailed comparisons between reattachment length, velocity, pressure, turbulent kinetic energy, Reynolds shear stress, and skin friction predictions. The results indicated that the use of a wall function for the standard k-epsilon technique did not reduce the calculation accuracy for this separated flow when compared to the low turbulent Reynolds number techniques.

Spontaneous rise in open rectangular channels under gravity.

PubMed

Thammanna Gurumurthy, Vignesh; Roisman, Ilia V; Tropea, Cameron; Garoff, Stephen

2018-05-17

Fluid movement in microfluidic devices, porous media, and textured surfaces involves coupled flows over the faces and corners of the media. Spontaneous wetting of simple grooved surfaces provides a model system to probe these flows. This numerical study investigates the spontaneous rise of a liquid in an array of open rectangular channels under gravity, using the Volume-of-Fluid method with adaptive mesh refinement. The rise is characterized by the meniscus height at the channel center, outer face and the interior and exterior corners. At lower contact angles and higher channel aspect ratios, the statics and dynamics of the rise in the channel center show little deviation with the classical model for capillarity, which ignores the existence of corners. For contact angles smaller than 45°, rivulets are formed in the interior corners and a cusp at the exterior corner. The rivulets at long times obey the one-third power law in time, with a weak dependence on the geometry. The cusp behaviour at the exterior corner transforms into a smooth meniscus when the capillary force is higher in the channel, even for contact angles smaller than 45°. The width of the outer face does not influence the capillary rise inside the channel, and the channel size does not influence the rise on the outer face. Copyright © 2018 Elsevier Inc. All rights reserved.

Distinct spatial frequency sensitivities for processing faces and emotional expressions.

PubMed

Vuilleumier, Patrik; Armony, Jorge L; Driver, Jon; Dolan, Raymond J

2003-06-01

High and low spatial frequency information in visual images is processed by distinct neural channels. Using event-related functional magnetic resonance imaging (fMRI) in humans, we show dissociable roles of such visual channels for processing faces and emotional fearful expressions. Neural responses in fusiform cortex, and effects of repeating the same face identity upon fusiform activity, were greater with intact or high-spatial-frequency face stimuli than with low-frequency faces, regardless of emotional expression. In contrast, amygdala responses to fearful expressions were greater for intact or low-frequency faces than for high-frequency faces. An activation of pulvinar and superior colliculus by fearful expressions occurred specifically with low-frequency faces, suggesting that these subcortical pathways may provide coarse fear-related inputs to the amygdala.

A family of variable step-size affine projection adaptive filter algorithms using statistics of channel impulse response

NASA Astrophysics Data System (ADS)

Shams Esfand Abadi, Mohammad; AbbasZadeh Arani, Seyed Ali Asghar

2011-12-01

This paper extends the recently introduced variable step-size (VSS) approach to the family of adaptive filter algorithms. This method uses prior knowledge of the channel impulse response statistic. Accordingly, optimal step-size vector is obtained by minimizing the mean-square deviation (MSD). The presented algorithms are the VSS affine projection algorithm (VSS-APA), the VSS selective partial update NLMS (VSS-SPU-NLMS), the VSS-SPU-APA, and the VSS selective regressor APA (VSS-SR-APA). In VSS-SPU adaptive algorithms the filter coefficients are partially updated which reduce the computational complexity. In VSS-SR-APA, the optimal selection of input regressors is performed during the adaptation. The presented algorithms have good convergence speed, low steady state mean square error (MSE), and low computational complexity features. We demonstrate the good performance of the proposed algorithms through several simulations in system identification scenario.

Large-eddy simulation of a backward facing step flow using a least-squares spectral element method

NASA Technical Reports Server (NTRS)

Chan, Daniel C.; Mittal, Rajat

1996-01-01

We report preliminary results obtained from the large eddy simulation of a backward facing step at a Reynolds number of 5100. The numerical platform is based on a high order Legendre spectral element spatial discretization and a least squares time integration scheme. A non-reflective outflow boundary condition is in place to minimize the effect of downstream influence. Smagorinsky model with Van Driest near wall damping is used for sub-grid scale modeling. Comparisons of mean velocity profiles and wall pressure show good agreement with benchmark data. More studies are needed to evaluate the sensitivity of this method on numerical parameters before it is applied to complex engineering problems.

Initial steps of inactivation at the K+ channel selectivity filter

PubMed Central

Thomson, Andrew S.; Heer, Florian T.; Smith, Frank J.; Hendron, Eunan; Bernèche, Simon; Rothberg, Brad S.

2014-01-01

K+ efflux through K+ channels can be controlled by C-type inactivation, which is thought to arise from a conformational change near the channel’s selectivity filter. Inactivation is modulated by ion binding near the selectivity filter; however, the molecular forces that initiate inactivation remain unclear. We probe these driving forces by electrophysiology and molecular simulation of MthK, a prototypical K+ channel. Either Mg2+ or Ca2+ can reduce K+ efflux through MthK channels. However, Ca2+, but not Mg2+, can enhance entry to the inactivated state. Molecular simulations illustrate that, in the MthK pore, Ca2+ ions can partially dehydrate, enabling selective accessibility of Ca2+ to a site at the entry to the selectivity filter. Ca2+ binding at the site interacts with K+ ions in the selectivity filter, facilitating a conformational change within the filter and subsequent inactivation. These results support an ionic mechanism that precedes changes in channel conformation to initiate inactivation. PMID:24733889

A special purpose knowledge-based face localization method

NASA Astrophysics Data System (ADS)

Hassanat, Ahmad; Jassim, Sabah

2008-04-01

This paper is concerned with face localization for visual speech recognition (VSR) system. Face detection and localization have got a great deal of attention in the last few years, because it is an essential pre-processing step in many techniques that handle or deal with faces, (e.g. age, face, gender, race and visual speech recognition). We shall present an efficient method for localization human's faces in video images captured on mobile constrained devices, under a wide variation in lighting conditions. We use a multiphase method that may include all or some of the following steps starting with image pre-processing, followed by a special purpose edge detection, then an image refinement step. The output image will be passed through a discrete wavelet decomposition procedure, and the computed LL sub-band at a certain level will be transformed into a binary image that will be scanned by using a special template to select a number of possible candidate locations. Finally, we fuse the scores from the wavelet step with scores determined by color information for the candidate location and employ a form of fuzzy logic to distinguish face from non-face locations. We shall present results of large number of experiments to demonstrate that the proposed face localization method is efficient and achieve high level of accuracy that outperforms existing general-purpose face detection methods.

A causal relationship between face-patch activity and face-detection behavior.

PubMed

Sadagopan, Srivatsun; Zarco, Wilbert; Freiwald, Winrich A

2017-04-04

The primate brain contains distinct areas densely populated by face-selective neurons. One of these, face-patch ML, contains neurons selective for contrast relationships between face parts. Such contrast-relationships can serve as powerful heuristics for face detection. However, it is unknown whether neurons with such selectivity actually support face-detection behavior. Here, we devised a naturalistic face-detection task and combined it with fMRI-guided pharmacological inactivation of ML to test whether ML is of critical importance for real-world face detection. We found that inactivation of ML impairs face detection. The effect was anatomically specific, as inactivation of areas outside ML did not affect face detection, and it was categorically specific, as inactivation of ML impaired face detection while sparing body and object detection. These results establish that ML function is crucial for detection of faces in natural scenes, performing a critical first step on which other face processing operations can build.

Distribution of cardiac sodium channels in clusters potentiates ephaptic interactions in the intercalated disc.

PubMed

Hichri, Echrak; Abriel, Hugues; Kucera, Jan P

2018-02-15

It has been proposed that ephaptic conduction, relying on interactions between the sodium (Na + ) current and the extracellular potential in intercalated discs, might contribute to cardiac conduction when gap junctional coupling is reduced, but this mechanism is still controversial. In intercalated discs, Na + channels form clusters near gap junction plaques, but the functional significance of these clusters has never been evaluated. In HEK cells expressing cardiac Na + channels, we show that restricting the extracellular space modulates the Na + current, as predicted by corresponding simulations accounting for ephaptic effects. In a high-resolution model of the intercalated disc, clusters of Na + channels that face each other across the intercellular cleft facilitate ephaptic impulse transmission when gap junctional coupling is reduced. Thus, our simulations reveal a functional role for the clustering of Na + channels in intercalated discs, and suggest that rearrangement of these clusters in disease may influence cardiac conduction. It has been proposed that ephaptic interactions in intercalated discs, mediated by extracellular potentials, contribute to cardiac impulse propagation when gap junctional coupling is reduced. However, experiments demonstrating ephaptic effects on the cardiac Na + current (I Na ) are scarce. Furthermore, Na + channels form clusters around gap junction plaques, but the electrophysiological significance of these clusters has never been investigated. In patch clamp experiments with HEK cells stably expressing human Na v 1.5 channels, we examined how restricting the extracellular space modulates I Na elicited by an activation protocol. In parallel, we developed a high-resolution computer model of the intercalated disc to investigate how the distribution of Na + channels influences ephaptic interactions. Approaching the HEK cells to a non-conducting obstacle always increased peak I Na at step potentials near the threshold of I Na activation

Characteristics of camel-gate structures with active doping channel profiles

NASA Astrophysics Data System (ADS)

Tsai, Jung-Hui; Lour, Wen-Shiung; Laih, Lih-Wen; Liu, Rong-Chau; Liu, Wen-Chau

1996-03-01

In this paper, we demonstrate the influence of channel doping profile on the performances of camel-gate field effect transistors (CAMFETs). For comparison, single and tri-step doping channel structures with identical doping thickness products are employed, while other parameters are kept unchanged. The results of a theoretical analysis show that the single doping channel FET with lightly doping active layer has higher barrier height and drain-source saturation current. However, the transconductance is decreased. For a tri-step doping channel structure, it is found that the output drain-source saturation current and the barrier height are enhanced. Furthermore, the relatively voltage independent performances are improved. Two CAMFETs with single and tri-step doping channel structures have been fabricated and discussed. The devices exhibit nearly voltage independent transconductances of 144 mS mm -1 and 222 mS mm -1 for single and tri-step doping channel CAMFETs, respectively. The operation gate voltage may extend to ± 1.5 V for a tri-step doping channel CAMFET. In addition, the drain current densities of > 750 and 405 mA mm -1 are obtained for the tri-step and single doping CAMFETs. These experimental results are inconsistent with theoretical analysis.

Static Longitudinal Stability of a Rocket Vehicle Having a Rear-Facing Step Ahead of the Stabilizing Fins

NASA Technical Reports Server (NTRS)

Keynton, Robert J.

1961-01-01

Tests were conducted at Mach numbers of 3.96 and 4.65 in the Langley Unitary Plan wind tunnel to determine the static longitudinal stability characteristics of a fin-stabilized rocket-vehicle configuration which had a rearward facing step located upstream of the fins. Two fin sizes and planforms, a delta and a clipped delta, were tested. The angle of attack was varied from 6 deg to -6 deg and the Reynolds number based on model 6 length was about 10 x 10. The configuration with the larger fins (clipped delta) had a center of pressure slightly rearward of and an initial normal-force-curve slope slightly higher than that of the configuration with the smaller fins (delta) as would be expected. Calculations of the stability parameters gave a slightly lower initial slope of the normal-force curve than measured data, probably because of boundary-layer separation ahead of the step. The calculated center of pressure agreed well with the measured data. Measured and calculated increments in the initial slope of the normal-force curve and in the center of pressure, due to changing fins, were in excellent agreement indicating that separated flow downstream of the step did not influence flow over the fins. This result was consistent with data from schlieren photographs.

Simulation of supersonic turbulent flow in the vicinity of an inclined backward-facing step

NASA Astrophysics Data System (ADS)

El-Askary, W. A.

2011-08-01

Large eddy simulation (LES) is a viable and powerful tool to analyse unsteady three-dimensional turbulent flows. In this article, the method of LES is used to compute a plane turbulent supersonic boundary layer subjected to different pressure gradients. The pressure gradients are generated by allowing the flow to pass in the vicinity of an expansion-compression ramp (inclined backward-facing step with leeward-face angle of 25°) for an upstream Mach number of 2.9. The inflow boundary condition is the main problem for all turbulent wall-bounded flows. An approach to solve this problem is to extract instantaneous velocities, temperature and density data from an auxiliary simulation (inflow generator). To generate an appropriate realistic inflow condition to the inflow generator itself the rescaling technique for compressible flows is used. In this method, Morkovin's hypothesis, in which the total temperature fluctuations are neglected compared with the static temperature fluctuations, is applied to rescale and generate the temperature profile at inlet. This technique was successfully developed and applied by the present author for an LES of subsonic three-dimensional boundary layer of a smooth curved ramp. The present LES results are compared with the available experimental data as well as numerical data. The positive impact of the rescaling formulation of the temperature is proven by the convincing agreement of the obtained results with the experimental data compared with published numerical work and sheds light on the quality of the developed compressible inflow generator.

Comprehensive Approach to Verification and Validation of CFD Simulations Applied to Backward Facing Step-Application of CFD Uncertainty Analysis

NASA Technical Reports Server (NTRS)

Groves, Curtis E.; LLie, Marcel; Shallhorn, Paul A.

2012-01-01

There are inherent uncertainties and errors associated with using Computational Fluid Dynamics (CFD) to predict the flow field and there is no standard method for evaluating uncertainty in the CFD community. This paper describes an approach to -validate the . uncertainty in using CFD. The method will use the state of the art uncertainty analysis applying different turbulence niodels and draw conclusions on which models provide the least uncertainty and which models most accurately predict the flow of a backward facing step.

Separated and Recovering Turbulent Boundary Layer Flow Behind a Backward Facing Step For Different Reynolds Numbers

NASA Technical Reports Server (NTRS)

Jovic, Srba; Kutler, Paul F. (Technical Monitor)

1994-01-01

Experimental results for a two-dimensional separated turbulent boundary layer behind a backward facing step for five different Reynolds numbers are reported. Results are presented in the form of tables, graphs and a floppy disk for an easy access of the data. Reynolds number based on the step height was varied by changing the reference velocity upstream of the step, U(sub o), and the step height, h. Hot-wire measurement techniques were used to measure three Reynolds stresses and four triple-velocity correlations. In addition, surface pressure and skin friction coefficients were measured. All hot-wire measurements were acquired in a measuring domain which excluded recirculating flow region due to the directional insensitivity of hot-wires. The downstream extent of the domain from the step was 51 h for the largest and I 14h for the smallest step height. This significant downstream length permitted extensive study of the flow recovery. Prediction of perturbed flows and their recovery is particularly attractive for popular turbulence models since variations of turbulence length and time scales and flow interactions in different regions are generally inadequately predicted. The data indicate that the flow in the free shear layer region behaves like the plane mixing layer up to about 2/3 of the mean reattachment length when the flow interaction with the wall commences the flow recovery to that of an ordinary turbulent boundary layer structure. These changes of the flow do not occur abruptly with the change of boundary conditions. A reattachment region represents a transitional region where the flow undergoes the most dramatic adjustments to the new boundary conditions. Large eddies, created in the upstream free-shear layer region, are being torn, recirculated, reentrained back into the main stream interacting with the incoming flow structure. It is foreseeable that it is quite difficult to describe the physics of this region in a rational and quantitative manner other

Response of ryanodine receptor channels to Ca2+ steps produced by rapid solution exchange.

PubMed Central

Laver, D R; Curtis, B A

1996-01-01

We used a flow method for Ca2+ activation of sheep cardiac and rabbit skeletal ryanodine receptor (RyR) channels in lipid bilayers, which activated RyRs in < 20 ms and maintained a steady [Ca2+] for 5 s. [Ca2+] was rapidly altered by flowing Ca(2+)-buffered solutions containing 100 or 200 microM Ca2+ from a perfusion tube inserted in the cis, myoplasmic chamber above the bilayer. During steps from 0.1 to 100 microM, [Ca2+] reached 0.3 microM (activation threshold) and 10 microM (maximum Po) in times consistent with predictions of a solution exchange model. Immediately following rapid RyR activation, Po was 0.67 (cardiac) and 0.45 (skeletal) at a holding voltage of +40 mV (cis/trans). Po then declined (at constant [Ca2+]) in 70% of channels (n = 25) with time constants ranging from .5 to 15 s. The mechanism for Po decline, whether it be adaptation or inactivation, was not determined in this study. cis, 2 mM Mg2+ reduced the initial Po for skeletal RyRs to 0.21 and marginally slowed the declining phase. During very rapid falls in [Ca2+] from mM (inhibited) to sub-microM (sub-activating) levels, skeletal RyR did not open. We conclude the RyR gates responsible for Ca(2+)-dependent activation and inhibition of skeletal RyRs can gate independently. Images FIGURE 1 FIGURE 8 PMID:8842211

From antidunes to step-pools

NASA Astrophysics Data System (ADS)

Recking, Alain; Leduc, Pauline

2014-05-01

Step-pools are bed morphologies that are typical in high-gradient streams , recognizable by a staircase-like longitudinal profile resulting from accumulation of cobbles and boulders that are transverse to the channel and alternating with pools containing finer sediments. Within the last two decades step-pools have been the subject of increased efforts to characterize their nature; however their origin is still in debate. Researchers have very soon suspected step-pools to be the residual form of antidunes produced during flooding, but this hypothesis was continuously contested. Other theories has been proposed, considering, that step-pool profile develops a maximum flow resistance, or that pools geometry is controlled by the energy of a falling jet, or that steps form by boulders accumulation in a channel-spanning manner. All these theories gave very satisfying results when compared with experimental data, but does it mean that the antidune theory should we abandoned? We performed new flume experiments on steep slopes to investigate the antidune origin for step-pools. Our experiments showed that step-pools can have several origins, depending on the flow conditions and sediment mixture used. In some circumstances antidunes were well observed but did not produce stable step-pools morphology. In many occasions, step-pools obtained in the flume were isolated step-pools, with no real apparent periodicity. Only a few flow and sediment conditions allowed us to reproduce trains of antidunes which stabilized at the flow recession to produce stable periodical step-pools. These conditions are presented and discussed.

Face-elicited ERPs and affective attitude: brain electric microstate and tomography analyses.

PubMed

Pizzagalli, D; Lehmann, D; Koenig, T; Regard, M; Pascual-Marqui, R D

2000-03-01

Although behavioral studies have demonstrated that normative affective traits modulate the processing of facial and emotionally charged stimuli, direct electrophysiological evidence for this modulation is still lacking. Event-related potential (ERP) data associated with personal, traitlike approach- or withdrawal-related attitude (assessed post-recording and 14 months later) were investigated in 18 subjects during task-free (i.e. unrequested, spontaneous) emotional evaluation of faces. Temporal and spatial aspects of 27 channel ERP were analyzed with microstate analysis and low resolution electromagnetic tomography (LORETA), a new method to compute 3 dimensional cortical current density implemented in the Talairach brain atlas. Microstate analysis showed group differences 132-196 and 196-272 ms poststimulus, with right-shifted electric gravity centers for subjects with negative affective attitude. During these (over subjects reliably identifiable) personality-modulated, face-elicited microstates, LORETA revealed activation of bilateral occipito-temporal regions, reportedly associated with facial configuration extraction processes. Negative compared to positive affective attitude showed higher activity right temporal; positive compared to negative attitude showed higher activity left temporo-parieto-occipital. These temporal and spatial aspects suggest that the subject groups differed in brain activity at early, automatic, stimulus-related face processing steps when structural face encoding (configuration extraction) occurs. In sum, the brain functional microstates associated with affect-related personality features modulate brain mechanisms during face processing already at early information processing stages.

Thin Film Complementary Metal Oxide Semiconductor (CMOS) Device Using a Single-Step Deposition of the Channel Layer

PubMed Central

Nayak, Pradipta K.; Caraveo-Frescas, J. A.; Wang, Zhenwei; Hedhili, M. N.; Wang, Q. X.; Alshareef, H. N.

2014-01-01

We report, for the first time, the use of a single step deposition of semiconductor channel layer to simultaneously achieve both n- and p-type transport in transparent oxide thin film transistors (TFTs). This effect is achieved by controlling the concentration of hydroxyl groups (OH-groups) in the underlying gate dielectrics. The semiconducting tin oxide layer was deposited at room temperature, and the maximum device fabrication temperature was 350°C. Both n and p-type TFTs showed fairly comparable performance. A functional CMOS inverter was fabricated using this novel scheme, indicating the potential use of our approach for various practical applications. PMID:24728223

Nonverbal channel use in communication of emotion: how may depend on why.

PubMed

App, Betsy; McIntosh, Daniel N; Reed, Catherine L; Hertenstein, Matthew J

2011-06-01

This study investigated the hypothesis that different emotions are most effectively conveyed through specific, nonverbal channels of communication: body, face, and touch. Experiment 1 assessed the production of emotion displays. Participants generated nonverbal displays of 11 emotions, with and without channel restrictions. For both actual production and stated preferences, participants favored the body for embarrassment, guilt, pride, and shame; the face for anger, disgust, fear, happiness, and sadness; and touch for love and sympathy. When restricted to a single channel, participants were most confident about their communication when production was limited to the emotion's preferred channel. Experiment 2 examined the reception or identification of emotion displays. Participants viewed videos of emotions communicated in unrestricted and restricted conditions and identified the communicated emotions. Emotion identification in restricted conditions was most accurate when participants viewed emotions displayed via the emotion's preferred channel. This study provides converging evidence that some emotions are communicated predominantly through different nonverbal channels. Further analysis of these channel-emotion correspondences suggests that the social function of an emotion predicts its primary channel: The body channel promotes social-status emotions, the face channel supports survival emotions, and touch supports intimate emotions.

Face-to-face handoff: improving transfer to the pediatric intensive care unit after cardiac surgery.

PubMed

Vergales, Jeffrey; Addison, Nancy; Vendittelli, Analise; Nicholson, Evelyn; Carver, D Jeannean; Stemland, Christopher; Hoke, Tracey; Gangemi, James

2015-01-01

The goal was to develop and implement a comprehensive, primarily face-to-face handoff process that begins in the operating room and concludes at the bedside in the intensive care unit (ICU) for pediatric patients undergoing congenital heart surgery. Involving all stakeholders in the planning phase, the framework of the handoff system encompassed a combination of a formalized handoff tool, focused process steps that occurred prior to patient arrival in the ICU, and an emphasis on face-to-face communication at the conclusion of the handoff. The final process was evaluated by the use of observer checklists to examine quality metrics and timing for all patients admitted to the ICU following cardiac surgery. The process was found to improve how various providers view the efficiency of handoff, the ease of asking questions at each step, and the overall capability to improve patient care regardless of overall surgical complexity. © 2014 by the American College of Medical Quality.

The Effect of Micro-ramps on Supersonic Flow over a Forward-Facing Step

NASA Astrophysics Data System (ADS)

Zhang, Qing-Hu; Yi, Shi-He; Zhu, Yang-Zhu; Chen, Zhi; Wu, Yu

2013-04-01

The effect of micro-ramp control on fully developed turbulent flow over a forward-facing step (FFS) is investigated in a supersonic low-noise wind tunnel at Mach number 3 using nano-tracer planar laser scattering (NPLS) and supersonic particle image velocimetry (PIV) techniques. High spatiotemporal resolution images and the average velocity profiles of supersonic flow over the FFS with and without the control of the micro-ramps are captured. The fine structures of both cases, including the coherent structures of fully developed boundary layer and the large-scale hairpin-like vortices originated from the micro-ramps as well as the interaction of shock waves with the large-scale structures, are revealed and compared. Based on the time-correlation images, the temporal and spatial evolutionary characteristics of the coherent structures are investigated. It is beneficial to understand the dynamic mechanisms of the separated flow and the control mechanisms of the micro-ramps. The size of the separation region is determined by the NPLS and PIV. The results indicate that the control of the micro-ramps is capable of delaying the separation and diminishing the extent of recirculation zone.

High-Speed Video Observations of a Natural Lightning Stepped Leader

NASA Astrophysics Data System (ADS)

Jordan, D. M.; Hill, J. D.; Uman, M. A.; Yoshida, S.; Kawasaki, Z.

2010-12-01

High-speed video images of one branch of a natural negative lightning stepped leader were obtained at a frame rate of 300 kfps (3.33 us exposure) on June 18th, 2010 at the International Center for Lightning Research and Testing (ICLRT) located on the Camp Blanding Army National Guard Base in north-central Florida. The images were acquired using a 20 mm Nikon lens mounted on a Photron SA1.1 high-speed camera. A total of 225 frames (about 0.75 ms) of the downward stepped leader were captured, followed by 45 frames of the leader channel re-illumination by the return stroke and subsequent decay following the ground attachment of the primary leader channel. Luminous characteristics of dart-stepped leader propagation in triggered lightning obtained by Biagi et al. [2009, 2010] and of long laboratory spark formation [e.g., Bazelyan and Raizer, 1998; Gallimberti et al., 2002] are evident in the frames of the natural lightning stepped leader. Space stems/leaders are imaged in twelve different frames at various distances in front of the descending leader tip, which branches into two distinct components 125 frames after the channel enters the field of view. In each case, the space stem/leader appears to connect to the leader tip above in the subsequent frame, forming a new step. Each connection is associated with significant isolated brightening of the channel at the connection point followed by typically three or four frames of upward propagating re-illumination of the existing leader channel. In total, at least 80 individual steps were imaged.

Face detection and eyeglasses detection for thermal face recognition

NASA Astrophysics Data System (ADS)

Zheng, Yufeng

2012-01-01

Thermal face recognition becomes an active research direction in human identification because it does not rely on illumination condition. Face detection and eyeglasses detection are necessary steps prior to face recognition using thermal images. Infrared light cannot go through glasses and thus glasses will appear as dark areas in a thermal image. One possible solution is to detect eyeglasses and to exclude the eyeglasses areas before face matching. In thermal face detection, a projection profile analysis algorithm is proposed, where region growing and morphology operations are used to segment the body of a subject; then the derivatives of two projections (horizontal and vertical) are calculated and analyzed to locate a minimal rectangle of containing the face area. Of course, the searching region of a pair of eyeglasses is within the detected face area. The eyeglasses detection algorithm should produce either a binary mask if eyeglasses present, or an empty set if no eyeglasses at all. In the proposed eyeglasses detection algorithm, block processing, region growing, and priori knowledge (i.e., low mean and variance within glasses areas, the shapes and locations of eyeglasses) are employed. The results of face detection and eyeglasses detection are quantitatively measured and analyzed using the manually defined ground truths (for both face and eyeglasses). Our experimental results shown that the proposed face detection and eyeglasses detection algorithms performed very well in contrast with the predefined ground truths.

Alternative face models for 3D face registration

NASA Astrophysics Data System (ADS)

Salah, Albert Ali; Alyüz, Neşe; Akarun, Lale

2007-01-01

3D has become an important modality for face biometrics. The accuracy of a 3D face recognition system depends on a correct registration that aligns the facial surfaces and makes a comparison possible. The best results obtained so far use a one-to-all registration approach, which means each new facial surface is registered to all faces in the gallery, at a great computational cost. We explore the approach of registering the new facial surface to an average face model (AFM), which automatically establishes correspondence to the pre-registered gallery faces. Going one step further, we propose that using a couple of well-selected AFMs can trade-off computation time with accuracy. Drawing on cognitive justifications, we propose to employ category-specific alternative average face models for registration, which is shown to increase the accuracy of the subsequent recognition. We inspect thin-plate spline (TPS) and iterative closest point (ICP) based registration schemes under realistic assumptions on manual or automatic landmark detection prior to registration. We evaluate several approaches for the coarse initialization of ICP. We propose a new algorithm for constructing an AFM, and show that it works better than a recent approach. Finally, we perform simulations with multiple AFMs that correspond to different clusters in the face shape space and compare these with gender and morphology based groupings. We report our results on the FRGC 3D face database.

Kruskal-Wallis-based computationally efficient feature selection for face recognition.

PubMed

Ali Khan, Sajid; Hussain, Ayyaz; Basit, Abdul; Akram, Sheeraz

2014-01-01

Face recognition in today's technological world, and face recognition applications attain much more importance. Most of the existing work used frontal face images to classify face image. However these techniques fail when applied on real world face images. The proposed technique effectively extracts the prominent facial features. Most of the features are redundant and do not contribute to representing face. In order to eliminate those redundant features, computationally efficient algorithm is used to select the more discriminative face features. Extracted features are then passed to classification step. In the classification step, different classifiers are ensemble to enhance the recognition accuracy rate as single classifier is unable to achieve the high accuracy. Experiments are performed on standard face database images and results are compared with existing techniques.

Sub-component modeling for face image reconstruction in video communications

NASA Astrophysics Data System (ADS)

Shiell, Derek J.; Xiao, Jing; Katsaggelos, Aggelos K.

2008-08-01

Emerging communications trends point to streaming video as a new form of content delivery. These systems are implemented over wired systems, such as cable or ethernet, and wireless networks, cell phones, and portable game systems. These communications systems require sophisticated methods of compression and error-resilience encoding to enable communications across band-limited and noisy delivery channels. Additionally, the transmitted video data must be of high enough quality to ensure a satisfactory end-user experience. Traditionally, video compression makes use of temporal and spatial coherence to reduce the information required to represent an image. In many communications systems, the communications channel is characterized by a probabilistic model which describes the capacity or fidelity of the channel. The implication is that information is lost or distorted in the channel, and requires concealment on the receiving end. We demonstrate a generative model based transmission scheme to compress human face images in video, which has the advantages of a potentially higher compression ratio, while maintaining robustness to errors and data corruption. This is accomplished by training an offline face model and using the model to reconstruct face images on the receiving end. We propose a sub-component AAM modeling the appearance of sub-facial components individually, and show face reconstruction results under different types of video degradation using a weighted and non-weighted version of the sub-component AAM.

Quantitative Comparisons of a Coarse-Grid LES with Experimental Data for Backward-Facing Step Flow

NASA Astrophysics Data System (ADS)

McDonough, J. M.

1999-11-01

A novel approach to LES employing an additive decomposition of both solutions and governing equations (similar to ``multi-level'' approaches of Dubois et al.,Dynamic Multilevel Methods and the Simulation of Turbulence, Cambridge University Press, 1999) is presented; its main structural features are lack of filtering of governing equations (instead, solutions are filtered to remove aliasing due to under resolution) and direct modeling of subgrid-scale primitive variables (rather than modeling their correlations) in the manner proposed by Hylin and McDonough (Int. J. Fluid Mech. Res. 26, 228-256, 1999). A 2-D implementation of this formalism is applied to the backward-facing step flow studied experimentally by Driver and Seegmiller (AIAA J. 23, 163-171, 1985) and Driver et al. (AIAA J. 25, 914-919, 1987), and run on grids sufficiently coarse to permit easy extension to 3-D, industrially-realistic problems. Comparisons of computed and experimental mean quantities (velocity profiles, turbulence kinetic energy, reattachment lengths, etc.) and effects of grid refinement will be presented.

Investigation of Particle Sampling Bias in the Shear Flow Field Downstream of a Backward Facing Step

NASA Technical Reports Server (NTRS)

Meyers, James F.; Kjelgaard, Scott O.; Hepner, Timothy E.

1990-01-01

The flow field about a backward facing step was investigated to determine the characteristics of particle sampling bias in the various flow phenomena. The investigation used the calculation of the velocity:data rate correlation coefficient as a measure of statistical dependence and thus the degree of velocity bias. While the investigation found negligible dependence within the free stream region, increased dependence was found within the boundary and shear layers. Full classic correction techniques over-compensated the data since the dependence was weak, even in the boundary layer and shear regions. The paper emphasizes the necessity to determine the degree of particle sampling bias for each measurement ensemble and not use generalized assumptions to correct the data. Further, it recommends the calculation of the velocity:data rate correlation coefficient become a standard statistical calculation in the analysis of all laser velocimeter data.

Flight-measured base pressure coefficients for thick boundary-layer flow over an aft-facing step for Mach numbers from 0.4 to 2.5

NASA Technical Reports Server (NTRS)

Goecke, S. A.

1973-01-01

A 0.56-inch thick aft-facing step was located 52.1 feet from the leading edge of the left wing of an XB-70 airplane. A boundary-layer rake at a mirror location on the right wing was used to obtain local flow properties. Reynolds numbers were near 10 to the 8th power, resulting in a relatively thick boundary-layer. The momentum thickness ranged from slightly thinner to slightly thicker than the step height. Surface static pressures forward of the step were obtained for Mach numbers near 0.9, 1.5, 2.0, and 2.4. The data were compared with thin boundary-layer results from flight and wind-tunnel experiments and semiempirical relationships. Significant differences were found between the thick and the thin boundary-layer data.

Observations of cleavage steps, slip traces and dislocation hollow cores on cleaved ?100? faces of ?-arginine phosphate monohydrate single crystals by atomic force microscopy

NASA Astrophysics Data System (ADS)

Sangwal, K.; Torrent-Burgués, J.; Sanz, F.; Servat, J.

1997-03-01

The results of an atomic force microscopy study of the nature of cleavage steps, observation of slip traces and formation of hollow cores at the centres of dislocations on the {100} faces of L-arginine phosphate monohydrate (LAP) single crystals grown from aqueous solutions are described and discussed. It was observed that: (1) most of the cleavage steps and all the slip traces are of elementary height, a = 1.085 nm; (2) the origin of a cleavage step may or may not have a hollow core; and (3) close to its origin, the curvature of a cleavage step may be positive or negative or may change from positive to negative. The results suggest that slip traces observed on the cleaved surfaces of LAP are formed during the cleavage process while the rounding and the rearrangement of elementary cleavage steps take place immediately after the occurrence of cleavage. Analysis of the results also shows that the dislocations responsible for the origin of hollow cores always represent a stress field state corresponding to a trapped solution of different local interface supersaturations.

An Experimental Study of a Separated/Reattached Flow Behind a Backward-Facing Step. Re(sub h) = 37,000

NASA Technical Reports Server (NTRS)

Jovic, Srba

1996-01-01

An experimental study was carried out to investigate turbulent structure of a two-dimensional incompressible separating/reattaching boundary layer behind a backward-facing step. Hot-wire measurement technique was used to measure three Reynolds stresses and higher-order mean products of velocity fluctuations. The Reynolds number, Re(sub h), based on the step height, h, and the reference velocity, U(sub 0), was 37,000. The upstream oncoming flow was fully developed turbulent boundary layer with the Re(sub theta) = 3600. All turbulent properties, such as Reynolds stresses, increase dramatically downstream of the step within an internally developing mixing layer. Distributions of dimensionless mean velocity, turbulent quantities and antisymmetric distribution of triple velocity products in the separated free shear layer suggest that the shear layer above the recirculating region strongly resembles free-shear mixing layer structure. In the reattachment region close to the wall, turbulent diffusion term balances the rate of dissipation since advection and production terms appear to be negligibly small. Further downstream, production and dissipation begin to dominate other transport processes near the wall indicating the growth of an internal turbulent boundary layer. In the outer region, however, the flow still has a memory of the upstream disturbance even at the last measuring station of 51 step-heights. The data show that the structure of the inner layer recovers at a much faster rate than the outer layer structure. The inner layer structure resembles the near-wall structure of a plane zero pressure-gradient turbulent boundary layer (plane TBL) by 25h to 30h, while the outer layer structure takes presumably over 100h.

Detonation Diffraction in a Multi-Step Channel

DTIC Science & Technology

2010-12-01

openings. This allowed the detonation wave diffraction transmission limits to be determined for hydrogen/air mixtures and to better understand...imaging systems to provide shock wave detail and velocity information. The images were observed through a newly designed explosive proof optical section...stepped openings. This allowed the detonation wave diffraction transmission limits to be determined for hydrogen/air mixtures and to better

Geomorphic and hydraulic Analyses of In-stream Step-pool Structures (I)

NASA Astrophysics Data System (ADS)

Kuo, W. C.; Hu, Y. L.; Wang, H. W.

2016-12-01

Longitudinal stair-like structures, such as alternating steps and pools, are found commonly in steep mountain streams. In a way to mimic the natural characteristics, many implementations of constructing artificial step structures have long been found in field practice to stabilize streambeds and enhance aquatic systems. To better understand how constructed step-pool systems form and function, this paper discusses the hydraulic and geomorphic factors based on flume experiments, and further compare to our field observations in Chijiawan Creek in Taiwan. We constructed a 2.9-m-long, 0.15-wide, and 0.3-m-high acrylic walled recirculating channel and conducted experiments to understand the formation, hydraulic features, and channel stability of step-pools of scenarios considering different channel slopes, discharges, feeding sediments. The results indicated that the keystones played a crucial role in stabilizing step-pool structures. The grain sizes of keystones from the experiments ranged approximately from one-third to one-tenth of channel width, while those from the field observations were about one-ninth to two-ninths. While the experimental discharge increased from 0.0012 cms to 0.006 cms, the flow transformed from nappe flow to skimming flow and the difference of average velocity between steps and pools reduced 30%. Besides, experiments showed that the step-pool structures failed immediately after keystones destroyed at a sediment transportation rate about 1.5 times of sediment feeding rate. It highlights the step-pools and channel stability is highly related to keystones. We further found the step-pools were buried at the experimental cases with coarse sediment fed upstream, similar to our field observations in Chijiawan Creek, with an approximately 1 3m deposition after Typhoon Soudelor, a 5-year event. The results obtained in this study would serve as a basis for ongoing discussions on how constructed step-pool structures would function and fail. More efforts

Stepped-to-dart Leaders in Cloud-to-ground Lightning

NASA Astrophysics Data System (ADS)

Stolzenburg, M.; Marshall, T. C.; Karunarathne, S.; Karunarathna, N.; Warner, T.; Orville, R. E.

2013-12-01

Using time-correlated high-speed video (50,000 frames per second) and fast electric field change (5 MegaSamples per second) data for lightning flashes in East-central Florida, we describe an apparently rare type of subsequent leader: a stepped leader that finds and follows a previously used channel. The observed 'stepped-to-dart leaders' occur in three natural negative ground flashes. Stepped-to-dart leader connection altitudes are 3.3, 1.6 and 0.7 km above ground in the three cases. Prior to the stepped-to-dart connection, the advancing leaders have properties typical of stepped leaders. After the connection, the behavior changes almost immediately (within 40-60 us) to dart or dart-stepped leader, with larger amplitude E-change pulses and faster average propagation speeds. In this presentation, we will also describe the upward luminosity after the connection in the prior return stroke channel and in the stepped leader path, along with properties of the return strokes and other leaders in the three flashes.

Modeling Face Identification Processing in Children and Adults.

ERIC Educational Resources Information Center

Schwarzer, Gudrun; Massaro, Dominic W.

2001-01-01

Two experiments studied whether and how 5-year-olds integrate single facial features to identify faces. Results indicated that children could evaluate and integrate information from eye and mouth features to identify a face when salience of features was varied. A weighted Fuzzy Logical Model of Perception fit better than a Single Channel Model,…

The numerical modeling of water/FMWCNT nanofluid flow and heat transfer in a backward-facing contracting channel

NASA Astrophysics Data System (ADS)

Alrashed, Abdullah A. A. A.; Akbari, Omid Ali; Heydari, Ali; Toghraie, Davood; Zarringhalam, Majid; Shabani, Gholamreza Ahmadi Sheikh; Seifi, Ali Reza; Goodarzi, Marjan

2018-05-01

In recent years, the study of rheological behavior and heat transfer of nanofluids in the industrial equipment has become widespread among the researchers and their results have led to great advancements in this field. In present study, the laminar flow and heat transfer of water/functional multi-walled carbon nanotube nanofluid have been numerically investigated in weight percentages of 0.00, 0.12 and 0.25 and Reynolds numbers of 1-150 by using finite volume method (FVM). The analyzed geometry is a two-dimensional backward-facing contracting channel and the effects of various weight percentages and Reynolds numbers have been studied in the supposed geometry. The results have been interpreted as the figures of Nusselt number, friction coefficient, pressure drop, velocity contours and static temperature. The results of this research indicate that, the enhancement of Reynolds number or weight percentage of nanoparticles causes the reduction of surface temperature and the enhancement of heat transfer coefficient. By increasing Reynolds number, the axial velocity enhances, causing the enhancement of momentum. By increasing fluid momentum at the beginning of channel, especially in areas close to the upper wall, the axial velocity reduces and the possibility of vortex generation increases. The mentioned behavior causes a great enhancement in velocity gradients and pressure drop at the inlet of channel. Also, in these areas, Nusselt number and local friction coefficient figures have a relative decline, which is due to the sudden reduction of velocity. In general, by increasing the mass fraction of solid nanoparticles, the average Nusselt number increases and in Reynolds number of 150, the enhancement of pumping power and pressure drop does not cause any significant changes. This behavior is an important advantage of choosing nanofluid which causes the enhancement of thermal efficiency.

Variation of the channel temperature in the transmission of lightning leader

NASA Astrophysics Data System (ADS)

Chang, Xuan; Yuan, Ping; Cen, Jianyong; Wang, Xuejuan

2017-06-01

According to the time-resolved spectra of the lightning stepped leader and dart leader processes, the channel temperature, its evolution characteristics with time and the variation along the channel height in the transmission process were analyzed. The results show that the stepped leader tip has a slightly higher temperature than the trailing end, which should be caused by a large amount of electric charges on the leader tip. In addition, both temperature and brightness are enhanced at the position of the channel node. The dart leader has a higher channel temperature than the stepped leader but a lower temperature than the return stroke. Meanwhile, the channel temperature of the dart leader obviously increases when the dart leader propagates to the ground.

Numerical solution of turbulent flow past a backward facing step using a nonlinear K-epsilon model

NASA Technical Reports Server (NTRS)

Speziale, C. G.; Ngo, Tuan

1987-01-01

The problem of turbulent flow past a backward facing step is important in many technological applications and has been used as a standard test case to evaluate the performance of turbulence models in the prediction of separated flows. It is well known that the commonly used kappa-epsilon (and K-l) models of turbulence yield inaccurate predictions for the reattachment points in this problem. By an analysis of the mean vorticity transport equation, it will be argued that the intrinsically inaccurate prediction of normal Reynolds stress differences by the Kappa-epsilon and K-l models is a major contributor to this problem. Computations using a new nonlinear kappa-epsilon model (which alleviates this deficiency) are made with the TEACH program. Comparisons are made between the improved results predicted by this nonlinear kappa-epsilon model and those obtained from the linear kappa-epsilon model as well as from second-order closure models.

Channel and Timeslot Co-Scheduling with Minimal Channel Switching for Data Aggregation in MWSNs

PubMed Central

Yeoum, Sanggil; Kang, Byungseok; Lee, Jinkyu; Choo, Hyunseung

2017-01-01

Collision-free transmission and efficient data transfer between nodes can be achieved through a set of channels in multichannel wireless sensor networks (MWSNs). While using multiple channels, we have to carefully consider channel interference, channel and time slot (resources) optimization, channel switching delay, and energy consumption. Since sensor nodes operate on low battery power, the energy consumed in channel switching becomes an important challenge. In this paper, we propose channel and time slot scheduling for minimal channel switching in MWSNs, while achieving efficient and collision-free transmission between nodes. The proposed scheme constructs a duty-cycled tree while reducing the amount of channel switching. As a next step, collision-free time slots are assigned to every node based on the minimal data collection delay. The experimental results demonstrate that the validity of our scheme reduces the amount of channel switching by 17.5%, reduces energy consumption for channel switching by 28%, and reduces the schedule length by 46%, as compared to the existing schemes. PMID:28471416

Channel and Timeslot Co-Scheduling with Minimal Channel Switching for Data Aggregation in MWSNs.

PubMed

Yeoum, Sanggil; Kang, Byungseok; Lee, Jinkyu; Choo, Hyunseung

2017-05-04

Collision-free transmission and efficient data transfer between nodes can be achieved through a set of channels in multichannel wireless sensor networks (MWSNs). While using multiple channels, we have to carefully consider channel interference, channel and time slot (resources) optimization, channel switching delay, and energy consumption. Since sensor nodes operate on low battery power, the energy consumed in channel switching becomes an important challenge. In this paper, we propose channel and time slot scheduling for minimal channel switching in MWSNs, while achieving efficient and collision-free transmission between nodes. The proposed scheme constructs a duty-cycled tree while reducing the amount of channel switching. As a next step, collision-free time slots are assigned to every node based on the minimal data collection delay. The experimental results demonstrate that the validity of our scheme reduces the amount of channel switching by 17.5%, reduces energy consumption for channel switching by 28%, and reduces the schedule length by 46%, as compared to the existing schemes.

Boulder-Faced Log Dams and other Alternatives for Gabion Check Dams in First-Order Ephemeral Streams with Coarse Bed Load in Ethiopia

NASA Astrophysics Data System (ADS)

Nyssen, Jan; Gebreslassie, Seifu; Assefa, Romha; Deckers, Jozef; Guyassa, Etefa; Poesen, Jean; Frankl, Amaury

2017-04-01

Many thousands of gabion check dams have been installed to control gully erosion in Ethiopia, but several challenges still remain, such as the issue of gabion failure in ephemeral streams with coarse bed load, that abrades at the chute step. As an alternative for gabion check dams in torrents with coarse bed load, boulder-faced log dams were conceived, installed transversally across torrents and tested (n = 30). For this, logs (22-35 cm across) were embedded in the banks of torrents, 0.5-1 m above the bed and their upstream sides were faced with boulders (0.3-0.7 m across). Similar to gabion check dams, boulder-faced log dams lead to temporary ponding, spreading of peak flow over the entire channel width and sediment deposition. Results of testing under extreme flow conditions (including two storms with return periods of 5.6 and 7 years) show that 18 dams resisted strong floods. Beyond certain flood thresholds, represented by proxies such as Strahler's stream order, catchment area, D95 or channel width), 11 log dams were completely destroyed. Smallholder farmers see much potential in this type of structure to control first-order torrents with coarse bed load, since the technique is cost-effective and can be easily installed.

First wide-angle view of channelized turbidity currents links migrating cyclic steps to flow characteristics

PubMed Central

Hughes Clarke, John E.

2016-01-01

Field observations of turbidity currents remain scarce, and thus there is continued debate about their internal structure and how they modify underlying bedforms. Here, I present the results of a new imaging method that examines multiple surge-like turbidity currents within a delta front channel, as they pass over crescent-shaped bedforms. Seven discrete flows over a 2-h period vary in speed from 0.5 to 3.0 ms−1. Only flows that exhibit a distinct acoustically attenuating layer at the base, appear to cause bedform migration. That layer thickens abruptly downstream of the bottom of the lee slope of the bedform, and the upper surface of the layer fluctuates rapidly at that point. The basal layer is inferred to reflect a strong near-bed gradient in density and the thickening is interpreted as a hydraulic jump. These results represent field-scale flow observations in support of a cyclic step origin of crescent-shaped bedforms. PMID:27283503

High accuracy step gauge interferometer

NASA Astrophysics Data System (ADS)

Byman, V.; Jaakkola, T.; Palosuo, I.; Lassila, A.

2018-05-01

Step gauges are convenient transfer standards for the calibration of coordinate measuring machines. A novel interferometer for step gauge calibrations implemented at VTT MIKES is described. The four-pass interferometer follows Abbe’s principle and measures the position of the inductive probe attached to a measuring head. The measuring head of the instrument is connected to a balanced boom above the carriage by a piezo translation stage. A key part of the measuring head is an invar structure on which the inductive probe and the corner cubes of the measuring arm of the interferometer are attached. The invar structure can be elevated so that the probe is raised without breaking the laser beam. During probing, the bending of the probe and the interferometer readings are recorded and the measurement face position is extrapolated to zero force. The measurement process is fully automated and the face positions of the steps can be measured up to a length of 2 m. Ambient conditions are measured continuously and the refractive index of air is compensated for. Before measurements the step gauge is aligned with an integrated 2D coordinate measuring system. The expanded uncertainty of step gauge calibration is U=\\sqrt{{{(64 nm)}2}+{{(88× {{10}-9}L)}2}} .

Effect of wall cooling on the stability of compressible subsonic flows over smooth humps and backward-facing steps

NASA Technical Reports Server (NTRS)

Al-Maaitah, Ayman A.; Nayfeh, Ali, H.; Ragab, Saad A.

1989-01-01

The effect of wall cooling on the two-dimensional linear stability of subsonic flows over two-dimensional surface imperfections is investigated. Results are presented for flows over smooth humps and backward-facing steps with Mach numbers up to 0.8. The results show that, whereas cooling decreases the viscous instability, it increases the shear-layer instability and hence it increases the growth rates in the separation region. The coexistence of more than one instability mechanism makes a certain degree of wall cooling most effective. For the Mach numbers 0.5 and 0.8, the optimum wall temperatures are about 80 pct and 60 pct of the adiabatic wall temperature, respectively. Increasing the Mach number decreases the effectiveness of cooling slightly and reduces the optimum wall temperature.

Analyzing Interactions by an IIS-Map-Based Method in Face-to-Face Collaborative Learning: An Empirical Study

ERIC Educational Resources Information Center

Zheng, Lanqin; Yang, Kaicheng; Huang, Ronghuai

2012-01-01

This study proposes a new method named the IIS-map-based method for analyzing interactions in face-to-face collaborative learning settings. This analysis method is conducted in three steps: firstly, drawing an initial IIS-map according to collaborative tasks; secondly, coding and segmenting information flows into information items of IIS; thirdly,…

What controls channel form in steep mountain streams?

NASA Astrophysics Data System (ADS)

Palucis, M. C.; Lamb, M. P.

2017-07-01

Steep mountain streams have channel morphologies that transition from alternate bar to step-pool to cascade with increasing bed slope, which affect stream habitat, flow resistance, and sediment transport. Experimental and theoretical studies suggest that alternate bars form under large channel width-to-depth ratios, step-pools form in near supercritical flow or when channel width is narrow compared to bed grain size, and cascade morphology is related to debris flows. However, the connection between these process variables and bed slope—the apparent dominant variable for natural stream types—is unclear. Combining field data and theory, we find that certain bed slopes have unique channel morphologies because the process variables covary systematically with bed slope. Multiple stable states are predicted for other ranges in bed slope, suggesting that a competition of underlying processes leads to the emergence of the most stable channel form.

Nanoscale dissolution and growth on anhydrite cleavage faces

NASA Astrophysics Data System (ADS)

Pina, Carlos M.

2009-12-01

In situ atomic force microscopy (AFM) was used to study the molecular-scale reactivity of anhydrite (1 0 0), (0 1 0), and (0 0 1) faces exposed to water and CaSO 4 aqueous solutions at room temperature. In pure water, dissolution occurs by step retreat and etch pit nucleation and growth. Both the kinetics of the step retreat and the shape of the etch pits are surface-specific and crystallographically controlled. In CaSO 4 aqueous solutions with concentrations ranging from 0.030 mol/l to 0.075 mol/l, the growth kinetics on anhydrite (1 0 0) and (0 1 0) faces was studied. Growth is also strongly controlled by crystallographic constraints and occurs exclusively from pre-existing step edges by highly anisotropic spreading of monolayers (˜3.5 Å in height). The AFM observations demonstrate that monolayer growth can occur on anhydrite (0 1 0) and (1 0 0) faces even from slightly supersaturated solutions. In addition, the comparison of the step kinetics on anhydrite faces shows that the mechanisms of step dissolution and growth are essentially the same, with the direction of migration of crystal building units being reversed at the anhydrite saturation point. Moreover, the analysis of both high resolution AFM images and lateral force microscopy (LFM) images confirms that the newly-formed monolayers are anhydrite growing in structural continuity with the original (1 0 0) and (0 1 0) surfaces. However, the formation of the first monolayers is metastable and two-dimensional nucleation and further multilayer growth of anhydrite are strongly inhibited even at high supersaturations.

Pleasant and unpleasant odour-face combinations influence face and odour perception: An event-related potential study.

PubMed

Cook, Stephanie; Kokmotou, Katerina; Soto, Vicente; Fallon, Nicholas; Tyson-Carr, John; Thomas, Anna; Giesbrecht, Timo; Field, Matt; Stancak, Andrej

2017-08-30

Odours alter evaluations of concurrent visual stimuli. However, neural mechanisms underlying the effects of congruent and incongruent odours on facial expression perception are not clear. Moreover, the influence of emotional faces on odour perception is not established. We investigated the effects of one pleasant and one unpleasant odour paired with happy and disgusted faces, on subjective ratings and ERP responses to faces. Participants rated the pleasantness of happy and disgusted faces that appeared during 3s pleasant or unpleasant odour pulses, or without odour. Odour pleasantness and intensity ratings were recorded in each trial. EEG was recorded continuously using a 128-channel system. Happy and disgusted faces paired with pleasant and unpleasant odour were rated as more or less pleasant, respectively, compared to the same faces presented in the other odour conditions. Odours were rated as more pleasant when paired with happy faces, and unpleasant odour was rated more intense when paired with disgusted faces. Unpleasant odour paired with disgusted faces also decreased inspiration. Odour-face interactions were evident in the N200 and N400 components. Our results reveal bi-directional effects of odours and faces, and suggest that odour-face interactions may be represented in ERP components. Pairings of unpleasant odour and disgusted faces resulted in stronger hedonic ratings, ERP changes, increased odour intensity ratings and respiratory adjustment. This finding likely represents heightened adaptive responses to multimodal unpleasant stimuli, prompting appropriate behaviour in the presence of danger. Copyright © 2017. Published by Elsevier B.V.

Entrainment effects in periodic forcing of the flow over a backward-facing step

NASA Astrophysics Data System (ADS)

Berk, T.; Medjnoun, T.; Ganapathisubramani, B.

2017-07-01

The effect of the Strouhal number on periodic forcing of the flow over a backward-facing step (height, H ) is investigated experimentally. Forcing is applied by a synthetic jet at the edge of the step at Strouhal numbers ranging from 0.21

Electrical properties of MOS devices fabricated on the 4H-SiC C-face.

NASA Astrophysics Data System (ADS)

Chen, Zengjun; Ahyi, A. C.; Williams, J. R.

2007-11-01

The electrical characteristics of MOS devices fabricated on the carbon face of 4H-SiC will be described. The C-face has a higher oxidation rate and a higher interface trap density compared to the Si-face. The thermal oxidation rate and the distribution of interface traps under different oxidation conditions will be discussed in this presentation. Sequential post-oxidation anneals in nitric oxide and hydrogen effectively reduces the interface density (Dit) near the conduction band edge. However, deeper in the band gap, the trap density remains higher compared to the Si-face. Time-dependent dielectric breakdown (TDDB) studies have also been performed to investigate oxide reliability on the C-face, and current-voltage measurements show that a low barrier height against carrier injection likely contributes to oxide degradation. Nevertheless, the effective channel mobility and threshold voltage for n-channel C-face lateral MOSFETs compare favorably with similar Si-face devices.

CNG channel subunit glycosylation regulates MMP-dependent changes in channel gating

PubMed Central

Meighan, Starla E.; Meighan, Peter C.; Rich, Elizabeth D.; Brown, R. Lane; Varnum, Michael D.

2013-01-01

Cyclic-nucleotide gated (CNG) channels are essential for phototransduction within retinal photoreceptors. We have demonstrated previously that enzymatic activity of matrix metalloproteinase-2 and -9, members of the MMP family of extracellular, Ca+2- and Zn+2-dependent proteases, enhances the ligand sensitivity of both rod (CNGA1 + CNGB1) and cone CNGA3 + CNGB3) CNG channels. Additionally, we have observed a decrease in maximal CNG channel current (IMAX) that begins late during MMP-directed gating changes. Here we demonstrate that CNG channels become non-conductive after prolonged MMP exposure. Concurrent with the loss of conductive channels is the increased relative contribution of channels exhibiting non-modified gating properties, suggesting the presence of a subpopulation of channels that are protected from MMP-induced gating effects. CNGA subunits are known to possess one extracellular core glycosylation site, located at one of two possible positions within the turret loop near the pore-forming region. Our results indicate that CNGA glycosylation can impede MMP-dependent modification of CNG channels. Furthermore, the relative position of the glycosylation site within the pore turret influences the extent of MMP-dependent proteolysis. Glycosylation at the site found in CNGA3 subunits was found to be protective, while glycosylation at the bovine CNGA1 site was not. Relocating the glycosylation site in CNGA1 to the position found in CNGA3 recapitulated CNGA3-like protection from MMP-dependent processing. Taken together, these data indicate that CNGA glycosylation may protect CNG channels from MMP-dependent proteolysis, consistent with MMP modification of channel function having a requirement for physical access to the extracellular face of the channel. PMID:24164424

Face recognition from unconstrained three-dimensional face images using multitask sparse representation

NASA Astrophysics Data System (ADS)

Bentaieb, Samia; Ouamri, Abdelaziz; Nait-Ali, Amine; Keche, Mokhtar

2018-01-01

We propose and evaluate a three-dimensional (3D) face recognition approach that applies the speeded up robust feature (SURF) algorithm to the depth representation of shape index map, under real-world conditions, using only a single gallery sample for each subject. First, the 3D scans are preprocessed, then SURF is applied on the shape index map to find interest points and their descriptors. Each 3D face scan is represented by keypoints descriptors, and a large dictionary is built from all the gallery descriptors. At the recognition step, descriptors of a probe face scan are sparsely represented by the dictionary. A multitask sparse representation classification is used to determine the identity of each probe face. The feasibility of the approach that uses the SURF algorithm on the shape index map for face identification/authentication is checked through an experimental investigation conducted on Bosphorus, University of Milano Bicocca, and CASIA 3D datasets. It achieves an overall rank one recognition rate of 97.75%, 80.85%, and 95.12%, respectively, on these datasets.

Lightning-channel conditioning

NASA Astrophysics Data System (ADS)

Sonnenfeld, R.; da Silva, C. L.; Eack, K.; Edens, H. E.; Harley, J.; McHarg, M.; Contreras Vidal, L.

2017-12-01

The concept of "conditioning" has several distinct applications in understanding lightning. It is commonly associated to the greater speed of dart-leaders vs. stepped leaders and the retrace of a cloud-to-ground channel by later return strokes. We will showadditional examples of conditioning: (A) High-speed videos of triggered flashes show "dark" periods of up to 50 ms between rebrightenings of an existing channel. (B) Interferometer (INTF) images of intra-cloud (IC) flashes demonstrate that electric-field "K-changes" correspond to rapid propagation of RF impulses along a previously formed channel separated by up to 20 ms with little RF emission on that channel. (C) Further, INTF images (like the one below) frequently show that the initial IC channel is more branched and "fuzzier'' than its later incarnations. Also, we contrast high-speed video, INTF observations, and spectroscopic measurements with possible physical mechanisms that can explain how channel conditioning guides and facilitates dart leader propagation. These mechanisms include: (1) a plasmochemical effect where electrons are stored in negative ions and released during the dart leader propagation via field-induced detachment; (2) small-amplitude residual currents that can maintain electrical conductivity; and (3) slow heat conduction cooling of plasma owing to channel expansion dynamics.

Step Bunching: Influence of Impurities and Solution Flow

NASA Technical Reports Server (NTRS)

Chernov, A. A.; Vekilov, P. G.; Coriell, S. R.; Murray, B. T.; McFadden, G. B.

1999-01-01

Step bunching results in striations even at relatively early stages of its development and in inclusions of mother liquor at the later stages. Therefore, eliminating step bunching is crucial for high crystal perfection. At least 5 major effects causing and influencing step bunching are known: (1) Basic morphological instability of stepped interfaces. It is caused by concentration gradient in the solution normal to the face and by the redistribution of solute tangentially to the interface which redistribution enhances occasional perturbations in step density due to various types of noise; (2) Aggravation of the above basic instability by solution flowing tangentially to the face in the same directions as the steps or stabilization of equidistant step train if these flows are antiparallel; (3) Enhanced bunching at supersaturation where step velocity v increases with relative supersaturation s much faster than linear. This v(s) dependence is believed to be associated with impurities. The impurities of which adsorption time is comparable with the time needed to deposit one lattice layer may also be responsible for bunching; (4) Very intensive solution flow stabilizes growing interface even at parallel solution and step flows; (5) Macrosteps were observed to nucleate at crystal corners and edges. Numerical simulation, assuming step-step interactions via surface diffusion also show that step bunching may be induced by random step nucleation at the facet edge and by discontinuity in the step density (a ridge) somewhere in the middle of a face. The corresponding bunching patterns produce the ones observed in experiment. The nature of step bunching generated at the corners and edges and by dislocation step sources, as well as the also relative importance and interrelations between mechanisms 1-5 is not clear, both from experimental and theoretical standpoints. Furthermore, several laws controlling the evolution of existing step bunches have been suggested, though

Flight-measured pressure characteristics of aft-facing steps in high Reynolds number flow at Mach numbers of 2.20, 2.50, and 2.80 and comparison with other data

NASA Technical Reports Server (NTRS)

Powers, S. G.

1978-01-01

The YF-12 airplane was studied to determine the pressure characteristics associated with an aft-facing step in high Reynolds number flow for nominal Mach numbers of 2.20, 2.50, and 2.80. Base pressure coefficients were obtained for three step heights. The surface static pressures ahead of and behind the step were measured for the no-step condition and for each of the step heights. A boundary layer rake was used to determine the local boundary layer conditions. The Reynolds number based on the length of flow ahead of the step was approximately 10 to the 8th power and the ratios of momentum thickness to step height ranged from 0.2 to 1.0. Base pressure coefficients were compared with other available data at similar Mach numbers and at ratios of momentum thickness to step height near 1.0. In addition, the data were compared with base pressure coefficients calculated by a semiempirical prediction method. The base pressure ratios are shown to be a function of Reynolds number based on momentum thickness. Profiles of the surface pressures ahead of and behind the step and the local boundary layer conditions are also presented.

The Internet and the Banks' Strategic Distribution Channel Decisions.

ERIC Educational Resources Information Center

Mols, Niels Peter

1998-01-01

Discusses two strategic distribution channel decisions facing banks, one regarding whether to target the Internet banking segment of customers versus the branch banking segment, and the other regarding the geographical area banks aim to serve. Future distribution channels, the change process, and local, national, and international strategies are…

Steps in Solution Growth: Revised Gibbs-Thomson Law, Turbulence and Morphological Stability

NASA Technical Reports Server (NTRS)

Chernov, A. A.; Rashkovich, L. N.; Vekilov, P. G.

2004-01-01

Two groups of new phenomena revealed by AFM and high resolution optical interferometry on crystal faces growing from solutions will be discussed. 1. Spacing between strongly polygonized spiral steps with low less than 10(exp -2) kink density on lysozyme and K- biphtalate do not follow the Burton-cabrera-Frank theory. The critical length of the yet immobile first Short step segment adjacent to a pinning defect (dislocation, stacking fault) is many times longer than that following from the step free energy. The low-kink density steps are typical of many growth conditions and materials, including low temperature gas phase epitaxy and MBE. 2. The step bunching pattern on the approx. 1 cm long { 110) KDP face growing from the turbulent solution flow (Re (triple bonds) 10(exp 4), solution flow rate approx. 1 m/s) suggests that the step bunch height does not increase infinitely as the bunch path on the crystal face rises, as is usually observed on large KDP crystals. The mechanism controlling the maximal bunch width and height is based on the drag of the solution depleted by the step bunch down thc solution stream. It includes splitting, coagulation and interlacing of bunches

Resurgent current of voltage-gated Na+ channels

PubMed Central

Lewis, Amanda H; Raman, Indira M

2014-01-01

Resurgent Na+ current results from a distinctive form of Na+ channel gating, originally identified in cerebellar Purkinje neurons. In these neurons, the tetrodotoxin-sensitive voltage-gated Na+ channels responsible for action potential firing have specialized mechanisms that reduce the likelihood that they accumulate in fast inactivated states, thereby shortening refractory periods and permitting rapid, repetitive, and/or burst firing. Under voltage clamp, step depolarizations evoke transient Na+ currents that rapidly activate and quickly decay, and step repolarizations elicit slower channel reopening, or a ‘resurgent’ current. The generation of resurgent current depends on a factor in the Na+ channel complex, probably a subunit such as NaVβ4 (Scn4b), which blocks open Na+ channels at positive voltages, competing with the fast inactivation gate, and unblocks at negative voltages, permitting recovery from an open channel block along with a flow of current. Following its initial discovery, resurgent Na+ current has been found in nearly 20 types of neurons. Emerging research suggests that resurgent current is preferentially increased in a variety of clinical conditions associated with altered cellular excitability. Here we review the biophysical, molecular and structural mechanisms of resurgent current and their relation to the normal functions of excitable cells as well as pathophysiology. PMID:25172941

Particle Image Velocimetry Measurements of a Two/Three-dimensional Separating/Reattaching Boundary Layer Downstream of an Axisymmetric Backward-facing Step

NASA Technical Reports Server (NTRS)

Hudy, Laura M.; Naguib, Ahmed M.; Humphreys, William M.; Bartram, Scott M.

2005-01-01

Planar Particle Image Velocimetry measurements were obtained in the separating/reattaching flow region downstream of an axisymmetric backward-facing step. Data were acquired for a two-dimensional (2D) separating boundary layer at five different Reynolds numbers based on step height (Re(sub h)), spanning 5900-33000, and for a three-dimensional (3D) separating boundary layer at Re(sub h) = 5980 and 8081. Reynolds number effects were investigated in the 2D cases using mean-velocity field, streamwise and wall-normal turbulent velocity, and Reynolds stress statistics. Results show that both the reattachment length (x(sub r)) and the secondary separation point are Reynolds number dependent. The reattachment length increased with rising Re(sub h) while the secondary recirculation region decreased in size. These and other Re(sub h) effects were interpreted in terms of changes in the separating boundary layer thickness and wall-shear stress. On the other hand, in the 3D case, it was found that the imposed cross-flow component was relatively weak in comparison to the streamwise component. As a result, the primary influences of three dimensionality only affected the near-separation region rather than the entire separation bubble.

Computation of Turbulent Recirculating Flow in Channels, and for Impingement Cooling

NASA Technical Reports Server (NTRS)

Chang, Byong Hoon

1992-01-01

Fully elliptic forms of the transport equations have been solved numerically for two flow configurations. The first is turbulent flow in a channel with transverse rectangular ribs, and the second is impingement cooling of a plane surface. Both flows are relevant to proposed designs for active cooling of hypersonic vehicles using supercritical hydrogen as the coolant. Flow downstream of an abrupt pipe expansion and of a backward-facing step were also solved with various near-wall turbulence models as benchmark problems. A simple form of periodicity boundary condition was used for the channel flow with transverse rectangular ribs. The effects of various parameters on heat transfer in channel flow with transverse ribs and in impingement cooling were investigated using the Yap modified Jones and Launder low Reynolds number k-epsilon turbulence model. For the channel flow, predictions were in adequate agreement with experiment for constant property flow, with the results for friction superior to those for heat transfer. For impingement cooling, the agreement with experiment was generally good, but the results suggest that improved modelling of the dissipation rate of turbulence kinetic energy is required in order to obtain improved heat transfer prediction, especially near the stagnation point. The k-epsilon turbulence model was used to predict the mean flow and heat transfer for constant and variable property flows. The effect of variable properties for channel flow was investigated using the same turbulence model, but comparison with experiment yielded no clear conclusions. Also, the wall function method was modified for use in the variable properties flow with a non-adiabatic surface, and an empirical model is suggested to correctly account for the behavior of the viscous sublayer with heating.

6. VIEW OF DAM 83, SHOWING OUTLET CHANNEL FLOWING INTO ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

6. VIEW OF DAM 83, SHOWING OUTLET CHANNEL FLOWING INTO POND A WITH DIVERSION GATES LONG EAST (LEFT) SIDE OF OUTLET CHANNEL, LOOKING SOUTH FROM DOWNSTREAM FACE OF THE DAM - Upper Souris National Wildlife Refuge, Dam 83, Souris River Basin, Foxholm, Surrey (England), ND

More than words (and faces): evidence for a Stroop effect of prosody in emotion word processing.

PubMed

Filippi, Piera; Ocklenburg, Sebastian; Bowling, Daniel L; Heege, Larissa; Güntürkün, Onur; Newen, Albert; de Boer, Bart

2017-08-01

Humans typically combine linguistic and nonlinguistic information to comprehend emotions. We adopted an emotion identification Stroop task to investigate how different channels interact in emotion communication. In experiment 1, synonyms of "happy" and "sad" were spoken with happy and sad prosody. Participants had more difficulty ignoring prosody than ignoring verbal content. In experiment 2, synonyms of "happy" and "sad" were spoken with happy and sad prosody, while happy or sad faces were displayed. Accuracy was lower when two channels expressed an emotion that was incongruent with the channel participants had to focus on, compared with the cross-channel congruence condition. When participants were required to focus on verbal content, accuracy was significantly lower also when prosody was incongruent with verbal content and face. This suggests that prosody biases emotional verbal content processing, even when conflicting with verbal content and face simultaneously. Implications for multimodal communication and language evolution studies are discussed.

6. View of south tower, facing south from Clover Island, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

6. View of south tower, facing south from Clover Island, across boat moorage channel. - Pasco-Kennewick Transmission Line, Columbia River Crossing Towers, Columbia Drive & Gum Street, Kennewick, Benton County, WA

Vertical Stability of Ephemeral Step-Pool Streams Largely Controlled By Tree Roots, Central Kentucky, USA

NASA Astrophysics Data System (ADS)

Macmannis, K. R.; Hawley, R. J.

2013-12-01

The mechanisms controlling stability on small streams in steep settings are not well documented but have many implications related to stream integrity and water quality. For example, channel instability on first and second order streams is a potential source of sediment in regulated areas with Total Maximum Daily Loads (TMDLs) on water bodies that are impaired for sedimentation, such as the Chesapeake Bay. Management strategies that preserve stream integrity and protect channel stability are critical to communities that may otherwise require large capital investments to meet TMDLs and other water quality criteria. To contribute to an improved understanding of ephemeral step-pool systems, we collected detailed hydrogeomorphic data on 4 steep (0.06 - 0.12 meter/meter) headwater streams draining to lower relief alluvial valleys in Spencer County, Kentucky, USA. The step-pool streams (mean step height of 0.47 meter, mean step spacing of 4 meters) drained small undeveloped catchments dominated by early successional forest. Data collection for each of the 4 streams included 2 to 3 cross section surveys, bed material particle counts at cross section locations, and profile surveys ranging from approximately 125 to 225 meters in length. All survey data was systematically processed to understand geometric parameters such as cross sectional area, depth, and top width; bed material gradations; and detailed profile measurements such as slope, pool and riffle lengths, pool spacing, pool depth, step height, and step length. We documented the location, frequency, and type of step-forming materials (i.e., large woody debris (LWD), rock, and tree roots), compiling a database of approximately 130 total steps. Lastly, we recorded a detailed tree assessment of all trees located within 2 meters of the top of bank, detailing the species of tree, trunk diameter, and approximate distance from the top of bank. Analysis of geometric parameters illustrated correlations between channel

A Wall of Faces

ERIC Educational Resources Information Center

Stevens, Lori

2008-01-01

Visitors to the campus of Orland High School (OHS) will never question that they have stepped into a world of the masses: kids, activity, personalities, busyness, and playfulness--a veritable cloud of mild bedlam. The wall of ceramic faces that greets a visitor in the school office is another reminder of the organized chaos that the teachers…

Face Recognition in Humans and Machines

NASA Astrophysics Data System (ADS)

O'Toole, Alice; Tistarelli, Massimo

The study of human face recognition by psychologists and neuroscientists has run parallel to the development of automatic face recognition technologies by computer scientists and engineers. In both cases, there are analogous steps of data acquisition, image processing, and the formation of representations that can support the complex and diverse tasks we accomplish with faces. These processes can be understood and compared in the context of their neural and computational implementations. In this chapter, we present the essential elements of face recognition by humans and machines, taking a perspective that spans psychological, neural, and computational approaches. From the human side, we overview the methods and techniques used in the neurobiology of face recognition, the underlying neural architecture of the system, the role of visual attention, and the nature of the representations that emerges. From the computational side, we discuss face recognition technologies and the strategies they use to overcome challenges to robust operation over viewing parameters. Finally, we conclude the chapter with a look at some recent studies that compare human and machine performances at face recognition.

Erosion and deposition by supercritical density flows during channel avulsion and backfilling: Field examples from coarse-grained deepwater channel-levée complexes (Sandino Forearc Basin, southern Central America)

NASA Astrophysics Data System (ADS)

Lang, Jörg; Brandes, Christian; Winsemann, Jutta

2017-03-01

Erosion and deposition by supercritical density flows can strongly impact the facies distribution and architecture of submarine fans. Field examples from coarse-grained channel-levée complexes from the Sandino Forearc Basin (southern Central America) show that cyclic-step and antidune deposits represent common sedimentary facies of these depositional systems and relate to the different stages of avulsion, bypass, levée construction and channel backfilling. During channel avulsion, large-scale scour-fill complexes (18 to 29 m deep, 18 to 25 m wide, 60 to > 120 m long) were incised by supercritical density flows. The multi-storey infill of the large-scale scour-fill complexes comprises amalgamated massive, normally coarse-tail graded or widely spaced subhorizontally stratified conglomerates and pebbly sandstones, interpreted as deposits of the hydraulic-jump zone of cyclic steps. The large-scale scour-fill complexes can be distinguished from small-scale channel fills based on the preservation of a steep upper margin and a coarse-grained infill comprising mainly amalgamated hydraulic-jump zone deposits. Channel fills include repeated successions deposited by cyclic steps with superimposed antidunes. The deposits of the hydraulic-jump zone of cyclic steps comprise regularly spaced scours (0.2 to 2.6 m deep, 0.8 to 23 m long) infilled by intraclast-rich conglomerates or pebbly sandstones, displaying normal coarse-tail grading or backsets. These deposits are laterally and vertically associated with subhorizontally stratified, low-angle cross-stratified or sinusoidally stratified sandstones and pebbly sandstones, which were deposited by antidunes on the stoss side of the cyclic steps during flow re-acceleration. The field examples indicate that so-called spaced stratified deposits may commonly represent antidune deposits with varying stratification styles controlled by the aggradation rate, grain-size distribution and amalgamation. The deposits of small-scale cyclic

Counter-facing plasma guns for efficient extreme ultra-violet plasma light source

NASA Astrophysics Data System (ADS)

Kuroda, Yusuke; Yamamoto, Akiko; Kuwabara, Hajime; Nakajima, Mitsuo; Kawamura, Tohru; Horioka, Kazuhiko

2013-11-01

A plasma focus system composed of a pair of counter-facing coaxial guns was proposed as a long-pulse and/or repetitive high energy density plasma source. We applied Li as the source of plasma for improvement of the conversion efficiency, the spectral purity, and the repetition capability. For operation of the system with ideal counter-facing plasma focus mode, we changed the system from simple coaxial geometry to a multi-channel configuration. We applied a laser trigger to make synchronous multi-channel discharges with low jitter. The results indicated that the configuration is promising to make a high energy density plasma with high spectral efficiency.

Sparse Feature Extraction for Pose-Tolerant Face Recognition.

PubMed

Abiantun, Ramzi; Prabhu, Utsav; Savvides, Marios

2014-10-01

Automatic face recognition performance has been steadily improving over years of research, however it remains significantly affected by a number of factors such as illumination, pose, expression, resolution and other factors that can impact matching scores. The focus of this paper is the pose problem which remains largely overlooked in most real-world applications. Specifically, we focus on one-to-one matching scenarios where a query face image of a random pose is matched against a set of gallery images. We propose a method that relies on two fundamental components: (a) A 3D modeling step to geometrically correct the viewpoint of the face. For this purpose, we extend a recent technique for efficient synthesis of 3D face models called 3D Generic Elastic Model. (b) A sparse feature extraction step using subspace modeling and ℓ1-minimization to induce pose-tolerance in coefficient space. This in return enables the synthesis of an equivalent frontal-looking face, which can be used towards recognition. We show significant performance improvements in verification rates compared to commercial matchers, and also demonstrate the resilience of the proposed method with respect to degrading input quality. We find that the proposed technique is able to match non-frontal images to other non-frontal images of varying angles.

Flow resistance dynamics in step‐pool stream channels: 1. Large woody debris and controls on total resistance

USGS Publications Warehouse

Wilcox, Andrew C.; Wohl, Ellen E.

2006-01-01

Flow resistance dynamics in step‐pool channels were investigated through physical modeling using a laboratory flume. Variables contributing to flow resistance in step‐pool channels were manipulated in order to measure the effects of various large woody debris (LWD) configurations, steps, grains, discharge, and slope on total flow resistance. This entailed nearly 400 flume runs, organized into a series of factorial experiments. Factorial analyses of variance indicated significant two‐way and three‐way interaction effects between steps, grains, and LWD, illustrating the complexity of flow resistance in these channels. Interactions between steps and LWD resulted in substantially greater flow resistance for steps with LWD than for steps lacking LWD. LWD position contributed to these interactions, whereby LWD pieces located near the lip of steps, analogous to step‐forming debris in natural channels, increased the effective height of steps and created substantially higher flow resistance than pieces located farther upstream on step treads. Step geometry and LWD density and orientation also had highly significant effects on flow resistance. Flow resistance dynamics and the resistance effect of bed roughness configurations were strongly discharge‐dependent; discharge had both highly significant main effects on resistance and highly significant interactions with all other variables.

Mechanosensory calcium-selective cation channels in epidermal cells

NASA Technical Reports Server (NTRS)

Ding, J. P.; Pickard, B. G.

1993-01-01

This paper explores the properties and likely functions of an epidermal Ca(2+)-selective cation channel complex activated by tension. As many as eight or nine linked or linkable equivalent conductance units or co-channels can open together. Open time for co-channel quadruplets and quintuplets tends to be relatively long with millimolar Mg2+ (but not millimolar Ca2+) at the cytosolic face of excised plasma membrane. Sensitivity to tension is regulated by transmembrane voltage and temperature. Under some circumstances channel activity is sychronized in rhythmic pulses. Certain lanthanides and a cytoskeleton-disturbing herbicide that inhibit gravitropic reception act on the channel system at low concentrations. Specifically, ethyl-N-phenylcarbamate promotes tension-dependent activity at micromolar levels. With moderate suction, Gd3+ provided at about 0.5 micromole at the extracellular face of the membrane promotes for several seconds but may then become inhibitory. Provision at 1-2 micromoles promotes and subsequently inhibits more vigorously (often abruptly and totally), and at high levels inhibits immediately. La3+, a poor gravitropic inhibitor, acts similarly but much more gradually and only at much higher concentrations. These properties, particularly these susceptibilities to modulation, indicate that in vivo the mechanosensitive channel must be mechanosensory and mechanoregulatory. It could serve to transduce the shear forces generated in the integrated wall-membrane-cytoskeleton system during turgor changes and cell expansion as well as transducing the stresses induced by gravity, touch and flexure. In so far as such transduction is modulated by voltage and temperature, the channels would also be sensors for these modalities as long as the wall-membrane-cytoskeleton system experiences mechanical stress.

3. View of north tower, facing north across the main ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. View of north tower, facing north across the main channel of the Columbus River from Clover Island. - Pasco-Kennewick Transmission Line, Columbia River Crossing Towers, Columbia Drive & Gum Street, Kennewick, Benton County, WA

Power module assemblies with staggered coolant channels

DOEpatents

Herron, Nicholas Hayden; Mann, Brooks S; Korich, Mark D

2013-07-16

A manifold is provided for supporting a power module assembly with a plurality of power modules. The manifold includes a first manifold section. The first face of the first manifold section is configured to receive the first power module, and the second face of the first manifold section defines a first cavity with a first baseplate thermally coupled to the first power module. The first face of the second manifold section is configured to receive the second power module, and the second face of the second manifold section defines a second cavity with a second baseplate thermally coupled to the second power module. The second face of the first manifold section and the second face of the second manifold section are coupled together such that the first cavity and the second cavity form a coolant channel. The first cavity is at least partially staggered with respect to second cavity.

Biophysical Interactions within Step-Pool Mountain Streams Following Wildfire

NASA Astrophysics Data System (ADS)

Parker, A.; Chin, A.; O'Dowd, A. P.

2014-12-01

Recovery of riverine ecosystems following disturbance is driven by a variety of interacting processes. Wildfires pose increasing disturbances to riverine landscapes, with rising frequencies and magnitudes owing to warming climates and increased fuel loads. The effects of wildfire include loss of vegetation, elevated runoff and flash floods, erosion and deposition, and changing biological habitats and communities. Understanding process interactions in post-fire landscapes is increasingly urgent for successful management and restoration of affected ecosystems. In steep channels, steps and pools provide prominent habitats for organisms and structural integrity in high energy environments. Step-pools are typically stable, responding to extreme events with recurrence intervals often exceeding 50 years. Once wildfire occurs, however, intensification of post-fire flood events can potentially overpower the inherent stability of these systems, with significant consequences for aquatic life and human well-being downstream. This study examined the short-term response of step-pool streams following the 2012 Waldo Canyon Fire in Colorado. We explored interacting feedbacks among geomorphology, hydrology, and ecology in the post-fire environment. At selected sites with varying burn severity, we established baseline conditions immediately after the fire with channel surveys, biological assessment using benthic macroinvertebrates, sediment analysis including pebble counts, and precipitation gauging. Repeat measurements after major storm events over several years enabled analysis of the interacting feedbacks among post-fire processes. We found that channels able to retain the step-pool structure changed less and facilitated recovery more readily. Step habitats maintained higher percentages of sensitive macroinvertebrate taxa compared to pools through post-fire floods. Sites burned with high severity experienced greater reduction in the percentage of sensitive taxa. The decimation of

Northern Hemisphere Gullies on West-Facing Crater Slope, Mars

NASA Image and Video Library

2010-06-09

This image from NASA Mars Reconnaissance Orbiter shows the west-facing side of an impact crater in the mid-latitudes of Mars northern hemisphere. This crater has gullies along its walls that are composed of alcoves, channels and debris aprons.

Voltage-gated Proton Channels

PubMed Central

DeCoursey, Thomas E.

2014-01-01

Voltage-gated proton channels, HV1, have vaulted from the realm of the esoteric into the forefront of a central question facing ion channel biophysicists, namely the mechanism by which voltage-dependent gating occurs. This transformation is the result of several factors. Identification of the gene in 2006 revealed that proton channels are homologues of the voltage-sensing domain of most other voltage-gated ion channels. Unique, or at least eccentric, properties of proton channels include dimeric architecture with dual conduction pathways, perfect proton selectivity, a single-channel conductance ~103 smaller than most ion channels, voltage-dependent gating that is strongly modulated by the pH gradient, ΔpH, and potent inhibition by Zn2+ (in many species) but an absence of other potent inhibitors. The recent identification of HV1 in three unicellular marine plankton species has dramatically expanded the phylogenetic family tree. Interest in proton channels in their own right has increased as important physiological roles have been identified in many cells. Proton channels trigger the bioluminescent flash of dinoflagellates, facilitate calcification by coccolithophores, regulate pH-dependent processes in eggs and sperm during fertilization, secrete acid to control the pH of airway fluids, facilitate histamine secretion by basophils, and play a signaling role in facilitating B-cell receptor mediated responses in B lymphocytes. The most elaborate and best-established functions occur in phagocytes, where proton channels optimize the activity of NADPH oxidase, an important producer of reactive oxygen species. Proton efflux mediated by HV1 balances the charge translocated across the membrane by electrons through NADPH oxidase, minimizes changes in cytoplasmic and phagosomal pH, limits osmotic swelling of the phagosome, and provides substrate H+ for the production of H2O2 and HOCl, reactive oxygen species crucial to killing pathogens. PMID:23798303

An Experimental Investigation On The Antidune Origin of Step-pools

NASA Astrophysics Data System (ADS)

Recking, A.; Leduc, P.

2013-12-01

Step-pools are bed morphologies that are typical in high-gradient streams , recognizable by a staircase-like longitudinal profile resulting from accumulation of cobbles and boulders that are transverse to the channel and alternating with pools containing finer sediments. Within the last two decades step-pools have been the subject of increased efforts to characterize their nature; however their origin is still in debate. Researchers have very soon suspected step-pools to be the residual form of antidunes produced during flooding, but this hypothesis was continuously contested. Other theories has been proposed, considering, that step-pool profile develops a maximum flow resistance, or that pools geometry is controlled by the energy of a falling jet, or that steps form by boulders accumulation in a channel-spanning manner. All these theories gave very satisfying results when compared with experimental data, but does it mean that the antidune theory should we abandoned? We performed new flume experiments on steep slopes to investigate the antidune origin for step-pools. Our experiments showed that step-pools can have several origins, depending on the flow conditions and sediment mixture used. In some circumstances antidunes were well observed but did not produce stable step-pools morphology. In many occasions, step-pools obtained in the flume were isolated step-pools, with no real apparent periodicity. Only a few flow and sediment conditions allowed us to reproduce trains of antidunes which stabilized at the flow recession to produce stable periodical step-pools. These conditions are presented and discussed.

22. View of Clark Fork Vehicle Bridge facing downwest side. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

22. View of Clark Fork Vehicle Bridge facing down-west side. Looking at road deck and vertical laced channel. - Clark Fork Vehicle Bridge, Spanning Clark Fork River, serves Highway 200, Clark Fork, Bonner County, ID

A smart technique for attendance system to recognize faces through parallelism

NASA Astrophysics Data System (ADS)

Prabhavathi, B.; Tanuja, V.; Madhu Viswanatham, V.; Rajashekhara Babu, M.

2017-11-01

Major part of recognising a person is face with the help of image processing techniques we can exploit the physical features of a person. In the old approach method that is used in schools and colleges it is there that the professor calls the student name and then the attendance for the students marked. Here in paper want to deviate from the old approach and go with the new approach by using techniques that are there in image processing. In this paper we presenting spontaneous presence for students in classroom. At first classroom image has been in use and after that image is kept in data record. For the images that are stored in the database we apply system algorithm which includes steps such as, histogram classification, noise removal, face detection and face recognition methods. So by using these steps we detect the faces and then compare it with the database. The attendance gets marked automatically if the system recognizes the faces.

Fast activation of dihydropyridine-sensitive calcium channels of skeletal muscle. Multiple pathways of channel gating

PubMed Central

1996-01-01

proposed for the DHP-sensitive Ca channel, which pictures the normal pathway of activation of the calcium channel as two voltage-dependent steps in sequence, plus a voltage-independent step which is rate limiting. The model reproduced well the fast and slow gating models of the calcium channel, and the effects of conditioning pulses. It is possible that the voltage-sensitive gating transitions of the DHP receptor, which occur early in the calcium channel activation sequence, could underlie the role of the voltage sensor and yield the rapid excitation-contraction coupling in skeletal muscle, through either electrostatic or allosteric linkage to the ryanodine receptors/calcium release channels. PMID:8882865

Cytoplasmic Domains and Voltage-Dependent Potassium Channel Gating

PubMed Central

Barros, Francisco; Domínguez, Pedro; de la Peña, Pilar

2012-01-01

The basic architecture of the voltage-dependent K+ channels (Kv channels) corresponds to a transmembrane protein core in which the permeation pore, the voltage-sensing components and the gating machinery (cytoplasmic facing gate and sensor–gate coupler) reside. Usually, large protein tails are attached to this core, hanging toward the inside of the cell. These cytoplasmic regions are essential for normal channel function and, due to their accessibility to the cytoplasmic environment, constitute obvious targets for cell-physiological control of channel behavior. Here we review the present knowledge about the molecular organization of these intracellular channel regions and their role in both setting and controlling Kv voltage-dependent gating properties. This includes the influence that they exert on Kv rapid/N-type inactivation and on activation/deactivation gating of Shaker-like and eag-type Kv channels. Some illustrative examples about the relevance of these cytoplasmic domains determining the possibilities for modulation of Kv channel gating by cellular components are also considered. PMID:22470342

Autistic Traits and Brain Activation during Face-to-Face Conversations in Typically Developed Adults

PubMed Central

Suda, Masashi; Takei, Yuichi; Aoyama, Yoshiyuki; Narita, Kosuke; Sakurai, Noriko; Fukuda, Masato; Mikuni, Masahiko

2011-01-01

Background Autism spectrum disorders (ASD) are characterized by impaired social interaction and communication, restricted interests, and repetitive behaviours. The severity of these characteristics is posited to lie on a continuum that extends into the general population. Brain substrates underlying ASD have been investigated through functional neuroimaging studies using functional magnetic resonance imaging (fMRI). However, fMRI has methodological constraints for studying brain mechanisms during social interactions (for example, noise, lying on a gantry during the procedure, etc.). In this study, we investigated whether variations in autism spectrum traits are associated with changes in patterns of brain activation in typically developed adults. We used near-infrared spectroscopy (NIRS), a recently developed functional neuroimaging technique that uses near-infrared light, to monitor brain activation in a natural setting that is suitable for studying brain functions during social interactions. Methodology We monitored regional cerebral blood volume changes using a 52-channel NIRS apparatus over the prefrontal cortex (PFC) and superior temporal sulcus (STS), 2 areas implicated in social cognition and the pathology of ASD, in 28 typically developed participants (14 male and 14 female) during face-to-face conversations. This task was designed to resemble a realistic social situation. We examined the correlations of these changes with autistic traits assessed using the Autism-Spectrum Quotient (AQ). Principal Findings Both the PFC and STS were significantly activated during face-to-face conversations. AQ scores were negatively correlated with regional cerebral blood volume increases in the left STS during face-to-face conversations, especially in males. Conclusions Our results demonstrate successful monitoring of brain function during realistic social interactions by NIRS as well as lesser brain activation in the left STS during face-to-face conversations in typically

Autistic traits and brain activation during face-to-face conversations in typically developed adults.

PubMed

Suda, Masashi; Takei, Yuichi; Aoyama, Yoshiyuki; Narita, Kosuke; Sakurai, Noriko; Fukuda, Masato; Mikuni, Masahiko

2011-01-01

Autism spectrum disorders (ASD) are characterized by impaired social interaction and communication, restricted interests, and repetitive behaviours. The severity of these characteristics is posited to lie on a continuum that extends into the general population. Brain substrates underlying ASD have been investigated through functional neuroimaging studies using functional magnetic resonance imaging (fMRI). However, fMRI has methodological constraints for studying brain mechanisms during social interactions (for example, noise, lying on a gantry during the procedure, etc.). In this study, we investigated whether variations in autism spectrum traits are associated with changes in patterns of brain activation in typically developed adults. We used near-infrared spectroscopy (NIRS), a recently developed functional neuroimaging technique that uses near-infrared light, to monitor brain activation in a natural setting that is suitable for studying brain functions during social interactions. We monitored regional cerebral blood volume changes using a 52-channel NIRS apparatus over the prefrontal cortex (PFC) and superior temporal sulcus (STS), 2 areas implicated in social cognition and the pathology of ASD, in 28 typically developed participants (14 male and 14 female) during face-to-face conversations. This task was designed to resemble a realistic social situation. We examined the correlations of these changes with autistic traits assessed using the Autism-Spectrum Quotient (AQ). Both the PFC and STS were significantly activated during face-to-face conversations. AQ scores were negatively correlated with regional cerebral blood volume increases in the left STS during face-to-face conversations, especially in males. Our results demonstrate successful monitoring of brain function during realistic social interactions by NIRS as well as lesser brain activation in the left STS during face-to-face conversations in typically developed participants with higher levels of autistic

Modeling the stepping mechanism in negative lightning leaders

NASA Astrophysics Data System (ADS)

Iudin, Dmitry; Syssoev, Artem; Davydenko, Stanislav; Rakov, Vladimir

2017-04-01

It is well-known that the negative leaders develop in a step manner using a mechanism of the so-called space leaders in contrary to positive ones, which propagate continuously. Despite this fact has been known for about a hundred years till now no one had developed any plausible model explaining this asymmetry. In this study we suggest a model of the stepped development of the negative lightning leader which for the first time allows carrying out the numerical simulation of its evolution. The model is based on the probability approach and description of temporal evolution of the discharge channels. One of the key features of our model is accounting for the presence of so called space streamers/leaders which play a fundamental role in the formation of negative leader's steps. Their appearance becomes possible due to the accounting of potential influence of the space charge injected into the discharge gap by the streamer corona. The model takes into account an asymmetry of properties of negative and positive streamers which is based on well-known from numerous laboratory measurements fact that positive streamers need about twice weaker electric field to appear and propagate as compared to negative ones. An extinction of the conducting channel as a possible way of its evolution is also taken into account. This allows us to describe the leader channel's sheath formation. To verify the morphology and characteristics of the model discharge, we use the results of the high-speed video observations of natural negative stepped leaders. We can conclude that the key properties of the model and natural negative leaders are very similar.

Deep learning and face recognition: the state of the art

NASA Astrophysics Data System (ADS)

Balaban, Stephen

2015-05-01

Deep Neural Networks (DNNs) have established themselves as a dominant technique in machine learning. DNNs have been top performers on a wide variety of tasks including image classification, speech recognition, and face recognition.1-3 Convolutional neural networks (CNNs) have been used in nearly all of the top performing methods on the Labeled Faces in the Wild (LFW) dataset.3-6 In this talk and accompanying paper, I attempt to provide a review and summary of the deep learning techniques used in the state-of-the-art. In addition, I highlight the need for both larger and more challenging public datasets to benchmark these systems. Despite the ability of DNNs and autoencoders to perform unsupervised feature learning, modern facial recognition pipelines still require domain specific engineering in the form of re-alignment. For example, in Facebook's recent DeepFace paper, a 3D "frontalization" step lies at the beginning of the pipeline. This step creates a 3D face model for the incoming image and then uses a series of affine transformations of the fiducial points to "frontalize" the image. This step enables the DeepFace system to use a neural network architecture with locally connected layers without weight sharing as opposed to standard convolutional layers.6 Deep learning techniques combined with large datasets have allowed research groups to surpass human level performance on the LFW dataset.3, 5 The high accuracy (99.63% for FaceNet at the time of publishing) and utilization of outside data (hundreds of millions of images in the case of Google's FaceNet) suggest that current face verification benchmarks such as LFW may not be challenging enough, nor provide enough data, for current techniques.3, 5 There exist a variety of organizations with mobile photo sharing applications that would be capable of releasing a very large scale and highly diverse dataset of facial images captured on mobile devices. Such an "ImageNet for Face Recognition" would likely receive a warm

Fabrication technology of Si face and m face on 4H-SiC (0001) epi-layer based on molten KOH etching

NASA Astrophysics Data System (ADS)

Lin, Wen-kui; Zeng, Chun-hong; Sun, Yu-hua; Zhang, Xuan; Li, Zhe; Yang, Tao-tao; Ju, Tao; Zhang, Bao-shun

2018-02-01

Additional scattering of electrons in the complex MOSFET channel caused by off-cut angle of (0001) 4H-SiC wafer, makes accurate crystal face acquisition much desired. Molten KOH was used to etch the circular grooves on the SiC wafer surface in muffle furnace, and hexagonal grooves with SiC crystal symmetry were obtained. Average etching rates at 500°C along <11-20> and <1-100> direction were about 4.826 um/min and 4.112 um/min, respectively,with a etching anisotropy ratio of 1.18. The m face was obtained by controlling the etching time and Si face was obtained by selfstopping effect. The method we developed in this paper has potential applications in the accurate crystal face acquisition of (0001) 4H-SiC epi-wafer, and the preparation of structures based on 4H-SiC.

1. Northeast face of missile site control building, commonly known ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. Northeast face of missile site control building, commonly known as the missile site radar building, showing open blast door #BD2. This emergency escape, at stair no. 12, is NEMP/RFI-shielded and 16" thick. The large circle in the center is the radar face, also known as the antennae array aperture. The small circle to the right of the radar face is the "Q" channel. The antennae atop the turret provided lightning protection for the building - Stanley R. Mickelsen Safeguard Complex, Missile Site Control Building, Northeast of Tactical Road; southeast of Tactical Road South, Nekoma, Cavalier County, ND

Locating faces in color photographs using neural networks

NASA Astrophysics Data System (ADS)

Brown, Joe R.; Talley, Jim

1994-03-01

This paper summarizes a research effort in finding the locations and sizes of faces in color images (photographs, video stills, etc.) if, in fact, faces are presented. Scenarios for using such a system include serving as the means of localizing skin for automatic color balancing during photo processing or it could be used as a front-end in a customs port of energy context for a system which identified persona non grata given a database of known faces. The approach presented here is a hybrid system including: a neural pre-processor, some conventional image processing steps, and a neural classifier as the final face/non-face discriminator. Neither the training (containing 17,655 faces) nor the test (containing 1829 faces) imagery databases were constrained in their content or quality. The results for the pilot system are reported along with a discussion for improving the current system.

Channel formation by flow stripping: large-scale scour features along the Monterey East Channel and their relation to sediment waves

USGS Publications Warehouse

Fildani, A.; Normark, W.R.; Kostic, S.; Parker, G.

2006-01-01

The Monterey East system is formed by large-scale sediment waves deposited as a result of flows stripped from the deeply incised Monterey fan valley (Monterey Channel) at the apex of the Shepard Meander. The system is dissected by a linear series of steps that take the form of scour-shaped depressions ranging from 3·5 to 4·5 km in width, 3 to 6 km in length and from 80 to 200 m in depth. These giant scours are aligned downstream from a breech in the levee on the southern side of the Shepard Meander. The floor of the breech is only 150 m above the floor of the Monterey fan valley but more than 100 m below the levee crests resulting in significant flow stripping. Numerical modeling suggests that the steps in the Monterey East system were created by Froude-supercritical turbidity currents stripped from the main flow in the Monterey channel itself. Froude-supercritical flow over an erodible bed can be subject to an instability that gives rise to the formation of cyclic steps, i.e. trains of upstream-migrating steps bounded upstream and downstream by hydraulic jumps in the flow above them. The flow that creates these steps may be net-erosional or net-depositional. In the former case it gives rise to trains of scours such as those in the Monterey East system, and in the latter case it gives rise to the familiar trains of upstream-migrating sediment waves commonly seen on submarine levees. The Monterey East system provides a unique opportunity to introduce the concept of cyclic steps in the submarine environment to study processes that might result in channel initiation on modern submarine fans.

The role of upper-regime flow bedforms in the morphodynamics of submarine channels

NASA Astrophysics Data System (ADS)

Covault, Jacob A.; Kostic, Svetlana; Fildani, Andrea

2014-05-01

Advances in acoustic imaging of submarine canyons and channels have provided accurate renderings of seafloor geomorphology. Still, a fundamental understanding of channel inception, evolution, sediment transport, and the nature of the currents traversing these channels remains elusive. Here, we review a mosaic of geomorphology, shallow stratigraphy, and morphodynamics of channelized deep-water depositional systems of tectonically active slopes offshore of California, USA. These systems are imaged in high-resolution multi-beam sonar bathymetry (dominant frequency ~200 kHz) and seismic-reflection (2-16 kHz) data. From north to south, the Monterey East, Lucia Chica, and San Mateo channelized deep-water depositional systems show a breadth of geomorphology and stratigraphic architecture, including channel reaches of varying sinuosity, levees, terraces within channels, and crescent-shaped bedforms, especially in the thalwegs of incipient channel elements. Morphodynamic numerical modeling is combined with interpretations of seafloor and shallow subsurface stratigraphic imagery to demonstrate that the crescent-shaped bedforms common to channel thalwegs are likely to be cyclic steps. We propose that net-erosional and net-depositional cyclic steps play a fundamental role in the formation, filling, and maintenance phases of submarine channels in continental margins with high gradient, locally rugose bathymetry. These margins include passive-margin slopes subjected to gravity-driven tectonic deformation. In such settings, high gradients support the development of densimetric Froude-supercritical turbidity currents, and abrupt slope breaks can promote hydraulic jumps and the spontaneous evolution of an erodible seabed into cyclic steps. This morphodynamic investigation of turbidity currents and the seafloor has the potential to enhance prediction of the locations, stratigraphic evolution, and architecture of submarine canyon-channel systems.

Bandwidth efficient channel estimation method for airborne hyperspectral data transmission in sparse doubly selective communication channels

NASA Astrophysics Data System (ADS)

Vahidi, Vahid; Saberinia, Ebrahim; Regentova, Emma E.

2017-10-01

A channel estimation (CE) method based on compressed sensing (CS) is proposed to estimate the sparse and doubly selective (DS) channel for hyperspectral image transmission from unmanned aircraft vehicles to ground stations. The proposed method contains three steps: (1) the priori estimate of the channel by orthogonal matching pursuit (OMP), (2) calculation of the linear minimum mean square error (LMMSE) estimate of the received pilots given the estimated channel, and (3) estimate of the complex amplitudes and Doppler shifts of the channel using the enhanced received pilot data applying a second round of a CS algorithm. The proposed method is named DS-LMMSE-OMP, and its performance is evaluated by simulating transmission of AVIRIS hyperspectral data via the communication channel and assessing their fidelity for the automated analysis after demodulation. The performance of the DS-LMMSE-OMP approach is compared with that of two other state-of-the-art CE methods. The simulation results exhibit up to 8-dB figure of merit in the bit error rate and 50% improvement in the hyperspectral image classification accuracy.

Sidedness of Carbamazepine Accessibility to Voltage-Gated Sodium Channels

PubMed Central

Jo, Sooyeon

2014-01-01

Voltage-gated sodium channels are inhibited by many local anesthetics, antiarrhythmics, and antiepileptic drugs. The local anesthetic lidocaine appears to be able to access its binding site in the sodium channel only from the membrane phase or from the internal face of the channel. In contrast, the antiepileptic drug carbamazepine was found to inhibit voltage-gated sodium channels only with external, but not internal, application, implying a major difference. We investigated this point using both whole-cell and inside-out patch recordings from human Nav1.7 channels in a stable cell line. In the whole-cell configuration, carbamazepine inhibited sodium current within seconds when applied externally, but had little or no effect when applied internally for up to 15 minutes, confirming previous results. However, carbamazepine inhibited sodium channels effectively and rapidly when applied to the internal face of the membrane using inside-out patch recording. We found that lidocaine also has little or no effect when applied intracellularly in whole-cell recording, but blocks effectively and rapidly when applied to the internal surface using inside-out patches. In contrast, the cationic lidocaine derivative QX-314 (N-ethyl-lidocaine) blocks effectively when applied internally with whole-cell dialysis, as well as when applied to inside-out patches. We conclude that carbamazepine and lidocaine access the sodium channel in similar ways and hypothesize that their lack of effect with internal dialysis in whole-cell recording reflects rapid exit through membrane near the pipette recording site. This effect likely limits the ability of any compound with significant membrane permeability to be applied intracellularly by whole-cell dialysis. PMID:24319110

23. View of Clark Fork Vehicle Bridge facing upwest side. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

23. View of Clark Fork Vehicle Bridge facing up-west side. Looking at structural connection of top chord, vertical laced channel and diagonal bars. - Clark Fork Vehicle Bridge, Spanning Clark Fork River, serves Highway 200, Clark Fork, Bonner County, ID

Expression-invariant representations of faces.

PubMed

Bronstein, Alexander M; Bronstein, Michael M; Kimmel, Ron

2007-01-01

Addressed here is the problem of constructing and analyzing expression-invariant representations of human faces. We demonstrate and justify experimentally a simple geometric model that allows to describe facial expressions as isometric deformations of the facial surface. The main step in the construction of expression-invariant representation of a face involves embedding of the facial intrinsic geometric structure into some low-dimensional space. We study the influence of the embedding space geometry and dimensionality choice on the representation accuracy and argue that compared to its Euclidean counterpart, spherical embedding leads to notably smaller metric distortions. We experimentally support our claim showing that a smaller embedding error leads to better recognition.

Binary zone-plate array for a parallel joint transform correlator applied to face recognition.

PubMed

Kodate, K; Hashimoto, A; Thapliya, R

1999-05-10

Taking advantage of small aberrations, high efficiency, and compactness, we developed a new, to our knowledge, design procedure for a binary zone-plate array (BZPA) and applied it to a parallel joint transform correlator for the recognition of the human face. Pairs of reference and unknown images of faces are displayed on a liquid-crystal spatial light modulator (SLM), Fourier transformed by the BZPA, intensity recorded on an optically addressable SLM, and inversely Fourier transformed to obtain correlation signals. Consideration of the bandwidth allows the relations among the channel number, the numerical aperture of the zone plates, and the pattern size to be determined. Experimentally a five-channel parallel correlator was implemented and tested successfully with a 100-person database. The design and the fabrication of a 20-channel BZPA for phonetic character recognition are also included.

The role of particle jamming on the formation and stability of step-pool morphology: insight from a reduced-complexity model

NASA Astrophysics Data System (ADS)

Saletti, M.; Molnar, P.; Hassan, M. A.

2017-12-01

Granular processes have been recognized as key drivers in earth surface dynamics, especially in steep landscapes because of the large size of sediment found in channels. In this work we focus on step-pool morphologies, studying the effect of particle jamming on step formation. Starting from the jammed-state hypothesis, we assume that grains generate steps because of particle jamming and those steps are inherently more stable because of additional force chains in the transversal direction. We test this hypothesis with a particle-based reduced-complexity model, CAST2, where sediment is organized in patches and entrainment, transport and deposition of grains depend on flow stage and local topography through simplified phenomenological rules. The model operates with 2 grain sizes: fine grains, that can be mobilized both my large and moderate flows, and coarse grains, mobile only during large floods. First, we identify the minimum set of processes necessary to generate and maintain steps in a numerical channel: (a) occurrence of floods, (b) particle jamming, (c) low sediment supply, and (d) presence of sediment with different entrainment probabilities. Numerical results are compared with field observations collected in different step-pool channels in terms of step density, a variable that captures the proportion of the channel occupied by steps. Not only the longitudinal profiles of numerical channels display step sequences similar to those observed in real step-pool streams, but also the values of step density are very similar when all the processes mentioned before are considered. Moreover, with CAST2 it is possible to run long simulations with repeated flood events, to test the effect of flood frequency on step formation. Numerical results indicate that larger step densities belong to system more frequently perturbed by floods, compared to system having a lower flood frequency. Our results highlight the important interactions between external hydrological forcing and

Do lightning positive leaders really "step"?

NASA Astrophysics Data System (ADS)

Petersen, D.

2015-12-01

It has been known for some time that positive leaders exhibit impulsive charge motion and optical emissions as they extend. However, laboratory and field observations have not produced any evidence of a process analogous to the space leader mechanism of negative leader extension. Instead, observations have suggested that the positive leader tip undergoes a continuous to intermittent series of corona streamer bursts, each burst resulting in a small forward extension of the positive leader channel. Traditionally, it has been held that lightning positive leaders extend in a continuous or quasi-continuous fashion. Lately, however, many have become concerned that this position is incongruous with observations of impulsive activity during lightning positive leader extension. It is increasingly suggested that this impulsive activity is evidence that positive leaders also undergo "stepping". There are two issues that must be addressed. The first issue concerns whether or not the physical processes underlying impulsive extension in negative and positive leaders are distinct. We argue that these processes are in fact physically distinct, and offer new high-speed video evidence to support this position. The second issue regards the proper use of the term "step" as an identifier for the impulsive forward extension of a leader. Traditional use of this term has been applied only to negative leaders, due primarily to their stronger impulsive charge motions and photographic evidence of clearly discontinuous forward progression of the luminous channel. Recently, due to the increasing understanding of the distinct "space leader" process of negative leader extension, the term "step" has increasingly come to be associated with the space leader process itself. Should this emerging association, "step" = space leader attachment, be canonized? If not, then it seems reasonable to use the term "step" to describe impulsive positive leader extension. If, however, we do wish to associate the

An autostratigraphic view of the long-term dynamics of delta distributary channels: A new step forward with the grade index model

NASA Astrophysics Data System (ADS)

Naruse, H.; Muto, T.

2017-12-01

Autostratigraphy is the stratigraphy that is generated by large-scale, deterministic autogenic processes of depositional systems, based on the full recognition of non-equilibrium behavior in response to steady external forcing. Recent experimental studies to explore the effects of basin water depth on the dynamics of distributary channels have brought a new geometrical scheme, here referred to as the grade index model, which is expected to make a significant step forward for development of the autostratigraphy of river deltas. Grade index (0 ≤ Gindex ≤1) is a dimensionless number that describes how close the alluvial river is to a graded state and is given as the ratio of subaerial allocation of the supplied sediment to both subaerial and subaqueous allocation of the sediment, in the form of a function of dimensionless basin water depth (h*). The grade index model for a particular geometrical setting suggests that as h* increase toward +∞, all of dimensionless magnitudes of delta progradation rate (Rpro*), alluvial aggradation rate (Ragg*), channel migration rate (Rmig*), avulsion frequency decrease toward 0, and all of dimensionless timescales of channel shifting (τs*), recurrence of channels (τr*), channel avulsion (τA*) increase toward +∞, and also that Rpro* = Ragg* = Rmig* = fA* = (τs*)-1 = (τr*)-1 = (τA* )-1 = Gindex. This grade index model, despite its simple structure, offers deep insight into the rationale of shoreline autoretreat, a typical large-scale, deterministic autogenic process that is realized by non-equilibrium response to steady base level rise. A simple geometrical modeling leads to a finding that Ppro* = (1 - Ab*) Gindex, where Ab* is a dimensionless form of the bottom surface of the deltaic deposit (Ab) given by dividing Ab with the square of autostratigraphic length scale (Λ). As the delta grows with base level rise, Ab progressively increases and then inevitably meets an event that Ab* exceeds 1 (i.e. Ab exceeds Λ2). We also

Audio-video feature correlation: faces and speech

NASA Astrophysics Data System (ADS)

Durand, Gwenael; Montacie, Claude; Caraty, Marie-Jose; Faudemay, Pascal

1999-08-01

This paper presents a study of the correlation of features automatically extracted from the audio stream and the video stream of audiovisual documents. In particular, we were interested in finding out whether speech analysis tools could be combined with face detection methods, and to what extend they should be combined. A generic audio signal partitioning algorithm as first used to detect Silence/Noise/Music/Speech segments in a full length movie. A generic object detection method was applied to the keyframes extracted from the movie in order to detect the presence or absence of faces. The correlation between the presence of a face in the keyframes and of the corresponding voice in the audio stream was studied. A third stream, which is the script of the movie, is warped on the speech channel in order to automatically label faces appearing in the keyframes with the name of the corresponding character. We naturally found that extracted audio and video features were related in many cases, and that significant benefits can be obtained from the joint use of audio and video analysis methods.

A randomized trial of face-to-face counselling versus telephone counselling versus bibliotherapy for occupational stress.

PubMed

Kilfedder, Catherine; Power, Kevin; Karatzias, Thanos; McCafferty, Aileen; Niven, Karen; Chouliara, Zoë; Galloway, Lisa; Sharp, Stephen

2010-09-01

The aim of the present study was to compare the effectiveness and acceptability of three interventions for occupational stress. A total of 90 National Health Service employees were randomized to face-to-face counselling or telephone counselling or bibliotherapy. Outcomes were assessed at post-intervention and 4-month follow-up. Clinical Outcomes in Routine Evaluation (CORE), General Health Questionnaire (GHQ-12), and Perceived Stress Scale (PSS-10) were used to evaluate intervention outcomes. An intention-to-treat analyses was performed. Repeated measures analysis revealed significant time effects on all measures with the exception of CORE Risk. No significant group effects were detected on all outcome measures. No time by group significant interaction effects were detected on any of the outcome measures with the exception of CORE Functioning and GHQ total. With regard to acceptability of interventions, participants expressed a preference for face-to-face counselling over the other two modalities. Overall, it was concluded that the three intervention groups are equally effective. Given that bibliotherapy is the least costly of the three, results from the present study might be considered in relation to a stepped care approach to occupational stress management with bibliotherapy as the first line of intervention, followed by telephone and face-to-face counselling as required.

'The right direction'. Primary-care docs see promise in CMS' proposed pay for non face-to-face work.

PubMed

Robeznieks, Andis

2013-07-15

The CMS has proposed paying physicians for managing patients apart from face-to-face office visits. Among the details under consideration are requiring practices to use an electronic health-record system that supports access to care, care coordination, care management and communications. "It's a step in the right direction. The devil will be in the details and, if the burden of documentation is so high, people may choose not to spend their time doing it," says Dr. Matt Handley, physician and medical director for quality at the Group Health Cooperative.

MIMO channel estimation and evaluation for airborne traffic surveillance in cellular networks

NASA Astrophysics Data System (ADS)

Vahidi, Vahid; Saberinia, Ebrahim

2018-01-01

A channel estimation (CE) procedure based on compressed sensing is proposed to estimate the multiple-input multiple-output sparse channel for traffic data transmission from drones to ground stations. The proposed procedure consists of an offline phase and a real-time phase. In the offline phase, a pilot arrangement method, which considers the interblock and block mutual coherence simultaneously, is proposed. The real-time phase contains three steps. At the first step, it obtains the priori estimate of the channel by block orthogonal matching pursuit; afterward, it utilizes that estimated channel to calculate the linear minimum mean square error of the received pilots. Finally, the block compressive sampling matching pursuit utilizes the enhanced received pilots to estimate the channel more accurately. The performance of the CE procedure is evaluated by simulating the transmission of traffic data through the communication channel and evaluating its fidelity for car detection after demodulation. Simulation results indicate that the proposed CE technique enhances the performance of the car detection in a traffic image considerably.

Survivorship in Non-Small Cell Lung Cancer: Challenges Faced and Steps Forward.

PubMed

Vijayvergia, Namrata; Shah, Prashant C; Denlinger, Crystal S

2015-09-01

Improvements in curative therapies and the advent of screening have led to increased numbers of non-small cell lung cancer (NSCLC) survivors. Most survivors have undergone invasive treatment (surgery, radiation therapy, and/or chemotherapy) and carry a higher comorbidity burden than survivors of other cancers. Overall quality of life (QOL) and health-related quality of life (HRQOL) suffer during the treatment phase, with the potential for long-term decline, and both clinical characteristics and treatment impact these measures. Physical and mental components of HRQOL seem to be most at risk for decline. The issues faced by survivors include physical symptoms such as respiratory issues, fatigue, hearing loss, neuropathy, and postsurgical pain; psychological distress leading to depression, financial issues, and poor compliance with recommended guidelines; and fear or risk of recurrence and secondary malignancies. This article summarizes the major issues faced by NSCLC survivors and suggests appropriate management. Future collaborative efforts are needed to further elucidate the complex issues that affect overall QOL and HRQOL in NSCLC survivors and to develop appropriate interventions in this large and diverse survivor population. Copyright © 2015 by the National Comprehensive Cancer Network.

Landscape response to rare flood events: a feedback cycle in channel-hillslope coupling

NASA Astrophysics Data System (ADS)

Golly, Antonius; Turowski, Jens; Hovius, Niels; Badoux, Alexandre

2017-04-01

Fluvial channels and the surrounding landscapes are in a permanent feedback relation, exchanging mass and energy. Only rarely we get the opportunity to observe the processes at work and study the underlying cause and effect relations. This is especially difficult, since processes can be highly non-linear, and the response to a trigger may occur after a lag time such that their correspondence is not immediately obvious. In the Erlenbach, a mountain stream in the Swiss Prealps, we study the mechanistic relations between in-channel hydrology, channel morphology, external climatic forcing and the surrounding sediment sources to identify relevant controls of sediment input and their characteristic scales. Here, we present time-lapse observations of a suspended slow-moving landslide complex with a direct connection to the channel. The channel-hillslope system was in a stable system state for several months. Only after a flood event, in which a channel step was eroded at the base of the hillslope, the hillslope was destabilized through debuttressing. As a consequence, the landslide was reactivated and entered a sustained phase of integral motion. The response phase ended when the landslide material reached the channel and formed a new channel step, re-buttressing the hillslope. The observations reveal that, at least in the Erlenbach, sediment input from the hillslopes is not a uniform process controlled by precipitation only. Instead, a perturbation of the system in form of the erosion of an alluvial channel step was necessary to initiate the feedback cycle. The observation illustrates the importance of a thorough identification of the process mechanics to understand the sediment dynamics and the formation of landscapes on long time-scales.

Single-step electrochemical functionalization of double-walled carbon nanotube (DWCNT) membranes and the demonstration of ionic rectification

PubMed Central

2013-01-01

Carbon nanotube (CNT) membranes allow the mimicking of natural ion channels for applications in drug delivery and chemical separation. Double-walled carbon nanotube membranes were simply functionalized with dye in a single step instead of the previous two-step functionalization. Non-faradic electrochemical impedance spectra indicated that the functionalized gatekeeper by single-step modification can be actuated to mimic the protein channel under bias. This functional chemistry was proven by a highly efficient ion rectification, wherein the highest experimental rectification factor of ferricyanide was up to 14.4. One-step functionalization by electrooxidation of amine provides a simple and promising functionalization chemistry for the application of CNT membranes. PMID:23758999

Development of Effective Connectivity during Own- and Other-Race Face Processing: A Granger Causality Analysis

PubMed Central

Zhou, Guifei; Liu, Jiangang; Ding, Xiao Pan; Fu, Genyue; Lee, Kang

2016-01-01

Numerous developmental studies have suggested that other-race effect (ORE) in face recognition emerges as early as in infancy and develops steadily throughout childhood. However, there is very limited research on the neural mechanisms underlying this developmental ORE. The present study used Granger causality analysis (GCA) to examine the development of children's cortical networks in processing own- and other-race faces. Children were between 3 and 13 years. An old-new paradigm was used to assess their own- and other-race face recognition with ETG-4000 (Hitachi Medical Co., Japan) acquiring functional near infrared spectroscopy (fNIRS) data. After preprocessing, for each participant and under each face condition, we obtained the causal map by calculating the weights of causal relations between the time courses of [oxy-Hb] of each pair of channels using GCA. To investigate further the differential causal connectivity for own-race faces and other-race faces at the group level, a repeated measure analysis of variance (ANOVA) was performed on the GCA weights for each pair of channels with the face race task (own-race face vs. other-race face) as the within-subject variable and the age as a between-subject factor (continuous variable). We found an age-related increase in functional connectivity, paralleling a similar age-related improvement in behavioral face processing ability. More importantly, we found that the significant differences in neural functional connectivity between the recognition of own-race faces and that of other-race faces were modulated by age. Thus, like the behavioral ORE, the neural ORE emerges early and undergoes a protracted developmental course. PMID:27713696

Stepwise strategy to improve Cervical Cancer Screening Adherence (SCAN-CC): automated text messages, phone calls and face-to-face interviews: protocol of a population-based randomised controlled trial.

PubMed

Firmino-Machado, João; Mendes, Romeu; Moreira, Amélia; Lunet, Nuno

2017-10-05

Screening is highly effective for cervical cancer prevention and control. Population-based screening programmes are widely implemented in high-income countries, although adherence is often low. In Portugal, just over half of the women adhere to cervical cancer screening, contributing for greater mortality rates than in other European countries. The most effective adherence raising strategies are based on patient reminders, small/mass media and face-to-face educational programmes, but sequential interventions targeting the general population have seldom been evaluated. The aim of this study is to assess the effectiveness of a stepwise approach, with increasing complexity and cost, to improve adherence to organised cervical cancer screening: step 1a-customised text message invitation; step 1b-customised automated phone call invitation; step 2-secretary phone call; step 3-family health professional phone call and face-to-face appointment. A population-based randomised controlled trial will be implemented in Portuguese urban and rural areas. Women eligible for cervical cancer screening will be randomised (1:1) to intervention and control. In the intervention group, women will be invited for screening through text messages, automated phone calls, manual phone calls and health professional appointments, to be applied sequentially to participants remaining non-adherent after each step. Control will be the standard of care (written letter). The primary outcome is the proportion of women adherent to screening after step 1 or sequences of steps from 1 to 3. The secondary outcomes are: proportion of women screened after each step (1a, 2 and 3); proportion of text messages/phone calls delivered; proportion of women previously screened in a private health institution who change to organised screening. The intervention and control groups will be compared based on intention-to-treat and per-protocol analyses. The study was approved by the Ethics Committee of the Northern Health

Video face recognition against a watch list

NASA Astrophysics Data System (ADS)

Abbas, Jehanzeb; Dagli, Charlie K.; Huang, Thomas S.

2007-10-01

Due to a large increase in the video surveillance data recently in an effort to maintain high security at public places, we need more robust systems to analyze this data and make tasks like face recognition a realistic possibility in challenging environments. In this paper we explore a watch-list scenario where we use an appearance based model to classify query faces from low resolution videos into either a watch-list or a non-watch-list face. We then use our simple yet a powerful face recognition system to recognize the faces classified as watch-list faces. Where the watch-list includes those people that we are interested in recognizing. Our system uses simple feature machine algorithms from our previous work to match video faces against still images. To test our approach, we match video faces against a large database of still images obtained from a previous work in the field from Yahoo News over a period of time. We do this matching in an efficient manner to come up with a faster and nearly real-time system. This system can be incorporated into a larger surveillance system equipped with advanced algorithms involving anomalous event detection and activity recognition. This is a step towards more secure and robust surveillance systems and efficient video data analysis.

Comparison of the structural properties of Zn-face and O-face single crystal homoepitaxial ZnO epilayers grown by RF-magnetron sputtering

NASA Astrophysics Data System (ADS)

Schifano, R.; Riise, H. N.; Domagala, J. Z.; Azarov, A. Yu.; Ratajczak, R.; Monakhov, E. V.; Venkatachalapathy, V.; Vines, L.; Chan, K. S.; Wong-Leung, J.; Svensson, B. G.

2017-01-01

Homoepitaxial ZnO growth is demonstrated from conventional RF-sputtering at 400 °C on both Zn and O polar faces of hydrothermally grown ZnO substrates. A minimum yield for the Rutherford backscattering and channeling spectrum, χmin, equal to ˜3% and ˜12% and a full width at half maximum of the 00.2 diffraction peak rocking curve of (70 ± 10) arc sec and (1400 ± 100) arc sec have been found for samples grown on the Zn and O face, respectively. The structural characteristics of the film deposited on the Zn face are comparable with those of epilayers grown by more complex techniques like molecular beam epitaxy. In contrast, the film simultaneously deposited on the O-face exhibits an inferior crystalline structure ˜0.7% strained in the c-direction and a higher atomic number contrast compared with the substrate, as revealed by high angle annular dark field imaging measurements. These differences between the Zn- and O-face films are discussed in detail and associated with the different growth mechanisms prevailing on the two surfaces.

The Effect of Acoustic Forcing on Instabilities and Breakdown in Swept-Wing Flow over a Backward-Facing Step

NASA Technical Reports Server (NTRS)

Eppink, Jenna L.; Shishkov, Olga; Wlezien, Richard W.; King, Rudolph A.; Choudhari, Meelan

2016-01-01

Instability interaction and breakdown were experimentally investigated in the flow over a swept backward-facing step. Acoustic forcing was used to excite the Tollmien-Schlichting (TS) instability and to acquire phase-locked results. The phase-averaged results illustrate the complex nature of the interaction between the TS and stationary cross flow instabilities. The weak stationary cross flow disturbance causes a distortion of the TS wavefront. The breakdown process is characterized by large positive and negative spikes in velocity. The positive spikes occur near the same time and location as the positive part of the TS wave. Higher-order spectral analysis was used to further investigate the nonlinear interactions between the TS instability and the traveling cross flow disturbances. The results reveal that a likely cause for the generation of the spikes corresponds to nonlinear interactions between the TS, traveling cross flow, and stationary cross flow disturbances. The spikes begin at low amplitudes of the unsteady and steady disturbances (2-4% U (sub e) (i.e. boundary layer edge velocity)) but can achieve very large amplitudes (20-30 percent U (sub e) (i.e. boundary layer edge velocity)) that initiate an early, though highly intermittent, breakdown to turbulence.

Providers and patients face-to-face: what is the time?

PubMed

Racine, Andrew D

2017-10-10

The frequency of visiting primary care providers and the duration of those visits varies substantially by patient demographics and across different developed countries. The significance of a cumulative measure of this time spent with providers in face-to-face visits is not well understood. In a recent IJHPR issue Nathan and co-authors have suggested a new metric for capturing the cumulative time spent annually in face-to-face encounters between providers and patients. The annual accumulated duration of time (AADC) of visits was constructed using a 2% random sample of adult patients from the Clalit health plan in Israel for the year 2012. The authors calculated the mean AADC to be 65.7 min with average visit durations of 7.6 min. A presumption underlying this analysis is that the metric captures the magnitude of activity devoted to eliciting relevant clinical information, synthesizing the significance of those data, and communicating the importance of that thinking to patients so that they might make informed decisions regarding their health care. But measuring the time spent with a provider is but a surrogate marker of these activities and the lack of correlation between time spent with providers and health outcomes suggests that as a surrogate it may not be that robust a measure. It is possible that what is being captured through this metric is the influence of economic incentives faced by individual practitioners and the structure of health care financing in different societies rather than a portrait either of clinical complexity or quality of care. The advent of this new measure of cumulative provider time with patients signals the importance of accurate measurement as a vital first step in understanding the meaning of data but reminds us of an obligation to inquire beyond the measurements themselves to arrive at appropriate policy-relevant conclusions.

Multi-stream face recognition for crime-fighting

NASA Astrophysics Data System (ADS)

Jassim, Sabah A.; Sellahewa, Harin

2007-04-01

Automatic face recognition (AFR) is a challenging task that is increasingly becoming the preferred biometric trait for identification and has the potential of becoming an essential tool in the fight against crime and terrorism. Closed-circuit television (CCTV) cameras have increasingly been used over the last few years for surveillance in public places such as airports, train stations and shopping centers. They are used to detect and prevent crime, shoplifting, public disorder and terrorism. The work of law-enforcing and intelligence agencies is becoming more reliant on the use of databases of biometric data for large section of the population. Face is one of the most natural biometric traits that can be used for identification and surveillance. However, variations in lighting conditions, facial expressions, face size and pose are a great obstacle to AFR. This paper is concerned with using waveletbased face recognition schemes in the presence of variations of expressions and illumination. In particular, we will investigate the use of a combination of wavelet frequency channels for a multi-stream face recognition using various wavelet subbands as different face signal streams. The proposed schemes extend our recently developed face veri.cation scheme for implementation on mobile devices. We shall present experimental results on the performance of our proposed schemes for a number of face databases including a new AV database recorded on a PDA. By analyzing the various experimental data, we shall demonstrate that the multi-stream approach is robust against variations in illumination and facial expressions than the previous single-stream approach.

Discriminative Projection Selection Based Face Image Hashing

NASA Astrophysics Data System (ADS)

Karabat, Cagatay; Erdogan, Hakan

Face image hashing is an emerging method used in biometric verification systems. In this paper, we propose a novel face image hashing method based on a new technique called discriminative projection selection. We apply the Fisher criterion for selecting the rows of a random projection matrix in a user-dependent fashion. Moreover, another contribution of this paper is to employ a bimodal Gaussian mixture model at the quantization step. Our simulation results on three different databases demonstrate that the proposed method has superior performance in comparison to previously proposed random projection based methods.

Broadband power amplifier tube: Klystron tube 5K70SK-WBT and step tuner VA-1470S

NASA Technical Reports Server (NTRS)

Cox, H. R.; Johnson, J. O.

1974-01-01

The design concept, the fabrication, and the acceptance testing of a wide band Klystron tube and remotely controlled step tuner for channel selection are discussed. The equipment was developed for the modification of an existing 20 KW Power Amplifier System which was provided to the contractor as GFE. The replacement Klystron covers a total frequency range of 2025 to 2120 MHz and is tuneable to six (6) each channel with a band width of 22 MHz or greater per channel. A 5 MHz overlap is provided between channels. Channels are selected at the control panel located in the front of the Klystron magnet or from one of three remote control stations connected in parallel with the step tuner. Included in this final report are the results of acceptance tests conducted at the vendor's plant and of the integrated system tests.

Nonlinear channelizer.

PubMed

In, Visarath; Longhini, Patrick; Kho, Andy; Neff, Joseph D; Leung, Daniel; Liu, Norman; Meadows, Brian K; Gordon, Frank; Bulsara, Adi R; Palacios, Antonio

2012-12-01

The nonlinear channelizer is an integrated circuit made up of large parallel arrays of analog nonlinear oscillators, which, collectively, serve as a broad-spectrum analyzer with the ability to receive complex signals containing multiple frequencies and instantaneously lock-on or respond to a received signal in a few oscillation cycles. The concept is based on the generation of internal oscillations in coupled nonlinear systems that do not normally oscillate in the absence of coupling. In particular, the system consists of unidirectionally coupled bistable nonlinear elements, where the frequency and other dynamical characteristics of the emergent oscillations depend on the system's internal parameters and the received signal. These properties and characteristics are being employed to develop a system capable of locking onto any arbitrary input radio frequency signal. The system is efficient by eliminating the need for high-speed, high-accuracy analog-to-digital converters, and compact by making use of nonlinear coupled systems to act as a channelizer (frequency binning and channeling), a low noise amplifier, and a frequency down-converter in a single step which, in turn, will reduce the size, weight, power, and cost of the entire communication system. This paper covers the theory, numerical simulations, and some engineering details that validate the concept at the frequency band of 1-4 GHz.

Face-to-face: Perceived personal relevance amplifies face processing

PubMed Central

Pittig, Andre; Schupp, Harald T.; Alpers, Georg W.

2017-01-01

Abstract The human face conveys emotional and social information, but it is not well understood how these two aspects influence face perception. In order to model a group situation, two faces displaying happy, neutral or angry expressions were presented. Importantly, faces were either facing the observer, or they were presented in profile view directed towards, or looking away from each other. In Experiment 1 (n = 64), face pairs were rated regarding perceived relevance, wish-to-interact, and displayed interactivity, as well as valence and arousal. All variables revealed main effects of facial expression (emotional > neutral), face orientation (facing observer > towards > away) and interactions showed that evaluation of emotional faces strongly varies with their orientation. Experiment 2 (n = 33) examined the temporal dynamics of perceptual-attentional processing of these face constellations with event-related potentials. Processing of emotional and neutral faces differed significantly in N170 amplitudes, early posterior negativity (EPN), and sustained positive potentials. Importantly, selective emotional face processing varied as a function of face orientation, indicating early emotion-specific (N170, EPN) and late threat-specific effects (LPP, sustained positivity). Taken together, perceived personal relevance to the observer—conveyed by facial expression and face direction—amplifies emotional face processing within triadic group situations. PMID:28158672

Face-to-face: Perceived personal relevance amplifies face processing.

PubMed

Bublatzky, Florian; Pittig, Andre; Schupp, Harald T; Alpers, Georg W

2017-05-01

The human face conveys emotional and social information, but it is not well understood how these two aspects influence face perception. In order to model a group situation, two faces displaying happy, neutral or angry expressions were presented. Importantly, faces were either facing the observer, or they were presented in profile view directed towards, or looking away from each other. In Experiment 1 (n = 64), face pairs were rated regarding perceived relevance, wish-to-interact, and displayed interactivity, as well as valence and arousal. All variables revealed main effects of facial expression (emotional > neutral), face orientation (facing observer > towards > away) and interactions showed that evaluation of emotional faces strongly varies with their orientation. Experiment 2 (n = 33) examined the temporal dynamics of perceptual-attentional processing of these face constellations with event-related potentials. Processing of emotional and neutral faces differed significantly in N170 amplitudes, early posterior negativity (EPN), and sustained positive potentials. Importantly, selective emotional face processing varied as a function of face orientation, indicating early emotion-specific (N170, EPN) and late threat-specific effects (LPP, sustained positivity). Taken together, perceived personal relevance to the observer-conveyed by facial expression and face direction-amplifies emotional face processing within triadic group situations. © The Author (2017). Published by Oxford University Press.

Method of forming a variable width channel

NASA Technical Reports Server (NTRS)

Andrews, James T. (Inventor)

1989-01-01

A method of forming a channel of varying width in a body comprises the steps of forming a plurality of masking elements having an opening therethrough intersecting a plurality of the elements on a surface of the body, partially flowing the elements into the opening to form a masking pattern having a variable width opening therethrough, and removing portions of the exposed body to form the channel with a sidewall having a surface contour corresponding to an edge of the masking pattern.

19. View of dedication plaque on the north tower facing ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

19. View of dedication plaque on the north tower facing south. The view is oblique because that portion of the approach trestles immediately in front of the plaque was removed in 1979. - Henry Ford Bridge, Spanning Cerritos Channel, Los Angeles-Long Beach Harbor, Los Angeles, Los Angeles County, CA

Affective attitudes to face images associated with intracerebral EEG source location before face viewing.

PubMed

Pizzagalli, D; Koenig, T; Regard, M; Lehmann, D

1999-01-01

We investigated whether different, personality-related affective attitudes are associated with different brain electric field (EEG) sources before any emotional challenge (stimulus exposure). A 27-channel EEG was recorded in 15 subjects during eyes-closed resting. After recording, subjects rated 32 images of human faces for affective appeal. The subjects in the first (i.e., most negative) and fourth (i.e., most positive) quartile of general affective attitude were further analyzed. The EEG data (mean=25+/-4. 8 s/subject) were subjected to frequency-domain model dipole source analysis (FFT-Dipole-Approximation), resulting in 3-dimensional intracerebral source locations and strengths for the delta-theta, alpha, and beta EEG frequency band, and for the full range (1.5-30 Hz) band. Subjects with negative attitude (compared to those with positive attitude) showed the following source locations: more inferior for all frequency bands, more anterior for the delta-theta band, more posterior and more right for the alpha, beta and 1.5-30 Hz bands. One year later, the subjects were asked to rate the face images again. The rating scores for the same face images were highly correlated for all subjects, and original and retest affective mean attitude was highly correlated across subjects. The present results show that subjects with different affective attitudes to face images had different active, cerebral, neural populations in a task-free condition prior to viewing the images. We conclude that the brain functional state which implements affective attitude towards face images as a personality feature exists without elicitors, as a continuously present, dynamic feature of brain functioning. Copyright 1999 Elsevier Science B.V.

Assessment of Emotional Expressions after Full-Face Transplantation.

PubMed

Topçu, Çağdaş; Uysal, Hilmi; Özkan, Ömer; Özkan, Özlenen; Polat, Övünç; Bedeloğlu, Merve; Akgül, Arzu; Döğer, Ela Naz; Sever, Refik; Barçın, Nur Ebru; Tombak, Kadriye; Çolak, Ömer Halil

2017-01-01

We assessed clinical features as well as sensory and motor recoveries in 3 full-face transplantation patients. A frequency analysis was performed on facial surface electromyography data collected during 6 basic emotional expressions and 4 primary facial movements. Motor progress was assessed using the wavelet packet method by comparison against the mean results obtained from 10 healthy subjects. Analyses were conducted on 1 patient at approximately 1 year after face transplantation and at 2 years after transplantation in the remaining 2 patients. Motor recovery was observed following sensory recovery in all 3 patients; however, the 3 cases had different backgrounds and exhibited different degrees and rates of sensory and motor improvements after transplant. Wavelet packet energy was detected in all patients during emotional expressions and primary movements; however, there were fewer active channels during expressions in transplant patients compared to healthy individuals, and patterns of wavelet packet energy were different for each patient. Finally, high-frequency components were typically detected in patients during emotional expressions, but fewer channels demonstrated these high-frequency components in patients compared to healthy individuals. Our data suggest that the posttransplantation recovery of emotional facial expression requires neural plasticity.

Calcium Channel Block by Cadmium in Chicken Sensory Neurons

NASA Astrophysics Data System (ADS)

Swandulla, D.; Armstrong, C. M.

1989-03-01

Cadmium block of calcium channels was studied in chicken dorsal root ganglion cells by a whole-cell patch clamp that provides high time resolution. Barium ion was the current carrier, and the channel type studied had a high threshold of activation and fast deactivation (type FD). Block of these channels by 20 μ M external Cd2+ is voltage dependent. Cd2+ ions can be cleared from blocked channels by stepping the membrane voltage (Vm) to a negative value. Clearing the channels is progressively faster and more complete as Vm is made more negative. Once cleared of Cd2+, the channels conduct transiently on reopening but reequilibrate with Cd2+ and become blocked within a few milliseconds. Cd2+ equilibrates much more slowly with closed channels, but at a holding potential of -80 mV virtually all channels are blocked at equilibrium. Cd2+ does not slow closing of the channels, as would be expected if it were necessary for Cd2+ to leave the channels before closing occurred. Instead, the data show unambiguously that the channel gate can close when the channel is Cd2+ occupied.

Feature level fusion of hand and face biometrics

NASA Astrophysics Data System (ADS)

Ross, Arun A.; Govindarajan, Rohin

2005-03-01

Multibiometric systems utilize the evidence presented by multiple biometric sources (e.g., face and fingerprint, multiple fingers of a user, multiple matchers, etc.) in order to determine or verify the identity of an individual. Information from multiple sources can be consolidated in several distinct levels, including the feature extraction level, match score level and decision level. While fusion at the match score and decision levels have been extensively studied in the literature, fusion at the feature level is a relatively understudied problem. In this paper we discuss fusion at the feature level in 3 different scenarios: (i) fusion of PCA and LDA coefficients of face; (ii) fusion of LDA coefficients corresponding to the R,G,B channels of a face image; (iii) fusion of face and hand modalities. Preliminary results are encouraging and help in highlighting the pros and cons of performing fusion at this level. The primary motivation of this work is to demonstrate the viability of such a fusion and to underscore the importance of pursuing further research in this direction.

The role of varying flow on channel morphology: a flume experiment

NASA Astrophysics Data System (ADS)

Hempel, L. A.; Grant, G.; Eaton, B. C.; Hassan, M. A.; Lewis, S.

2017-12-01

Numerous studies have explored how alluvial channels develop under different sediment and flow conditions, yet we still know very little about how channels adjust and respond to changing flow conditions. One reason for this oversight is the long-held idea that channels with complex flow regimes are adjusted to a single, channel-forming discharge. But growing evidence shows that channel form reflects time-dependent processes occuring over multiple flows. To better understand how stream channels adjust to a range of flows, and identify the timescales associated with those adjustments, we conducted a series of hydrograph experiments in a freely-adjustable flume that developed a self-formed, meander pattern with pool-riffle morphology. Hydrographs had different shapes, magnitudes, and durations, but the total sediment volume fed under equilibrium conditions was kept constant among experiments. We found that hydrograph shape controlled channel morphology, the rate of channel development, and degree of regularity in the pool-riffle pattern. Hydrographs with slowly rising rates of rise and fall produced channels that were equivalent in size to channels generated from constant flow experiments, and had regularly spaced pool-riffle and meander patterns, while hydrographs with fast rates of rise and fall produced undersized channels with a chaotic bed structure and pool-riffle pattern. The latter suggests that during quickly rising hydrographs, the flow rate increases faster than the channel capacity and planform pattern adjusts. We confirmed these observations by comparing the timescales associated with pool-riffle and planform curvature development, which were identified under simple, constant flow conditions, to the total duration of the hydrograph. Hydrographs with step durations equal to or longer than the channel adjustment time produced channels with a more regular pool-riffle patterns compared to channels with step durations shorter than the adjustment time. This

Hydraulic droplet coarsening in open-channel capillaries

NASA Astrophysics Data System (ADS)

Warren, Patrick B.

2016-11-01

Over a range of liquid-solid contact angles, an open-channel capillary with curved or angled sides can show a maximum in the Laplace pressure as a function of the filling state. Examples include double-angle wedges, grooves scored into flat surfaces, steps on surfaces, and the groove between touching parallel cylinders. The liquid in such a channel exhibits a beading instability if the channel is filled beyond the Laplace pressure maximum. The subsequent droplet coarsening takes place by hydraulic transport through the connecting liquid columns that remain in the groove. A mean-field scaling argument predicts the characteristic droplet radius R ˜t1 /7 , as a function of time t . This is confirmed by one-dimensional simulations of the coarsening kinetics. Some remarks are also made on the spreading kinetics of an isolated drop deposited in such a channel.

Retinal Cyclic Nucleotide-Gated Channels: From Pathophysiology to Therapy.

PubMed

Michalakis, Stylianos; Becirovic, Elvir; Biel, Martin

2018-03-07

The first step in vision is the absorption of photons by the photopigments in cone and rod photoreceptors. After initial amplification within the phototransduction cascade the signal is translated into an electrical signal by the action of cyclic nucleotide-gated (CNG) channels. CNG channels are ligand-gated ion channels that are activated by the binding of cyclic guanosine monophosphate (cGMP) or cyclic adenosine monophosphate (cAMP). Retinal CNG channels transduce changes in intracellular concentrations of cGMP into changes of the membrane potential and the Ca 2+ concentration. Structurally, the CNG channels belong to the superfamily of pore-loop cation channels and share a common gross structure with hyperpolarization-activated cyclic nucleotide-gated (HCN) channels and voltage-gated potassium channels (KCN). In this review, we provide an overview on the molecular properties of CNG channels and describe their physiological role in the phototransduction pathways. We also discuss insights into the pathophysiological role of CNG channel proteins that have emerged from the analysis of CNG channel-deficient animal models and human CNG channelopathies. Finally, we summarize recent gene therapy activities and provide an outlook for future clinical application.

Retinal Cyclic Nucleotide-Gated Channels: From Pathophysiology to Therapy

PubMed Central

Biel, Martin

2018-01-01

The first step in vision is the absorption of photons by the photopigments in cone and rod photoreceptors. After initial amplification within the phototransduction cascade the signal is translated into an electrical signal by the action of cyclic nucleotide-gated (CNG) channels. CNG channels are ligand-gated ion channels that are activated by the binding of cyclic guanosine monophosphate (cGMP) or cyclic adenosine monophosphate (cAMP). Retinal CNG channels transduce changes in intracellular concentrations of cGMP into changes of the membrane potential and the Ca2+ concentration. Structurally, the CNG channels belong to the superfamily of pore-loop cation channels and share a common gross structure with hyperpolarization-activated cyclic nucleotide-gated (HCN) channels and voltage-gated potassium channels (KCN). In this review, we provide an overview on the molecular properties of CNG channels and describe their physiological role in the phototransduction pathways. We also discuss insights into the pathophysiological role of CNG channel proteins that have emerged from the analysis of CNG channel-deficient animal models and human CNG channelopathies. Finally, we summarize recent gene therapy activities and provide an outlook for future clinical application. PMID:29518895

The own-age face recognition bias is task dependent.

PubMed

Proietti, Valentina; Macchi Cassia, Viola; Mondloch, Catherine J

2015-08-01

The own-age bias (OAB) in face recognition (more accurate recognition of own-age than other-age faces) is robust among young adults but not older adults. We investigated the OAB under two different task conditions. In Experiment 1 young and older adults (who reported more recent experience with own than other-age faces) completed a match-to-sample task with young and older adult faces; only young adults showed an OAB. In Experiment 2 young and older adults completed an identity detection task in which we manipulated the identity strength of target and distracter identities by morphing each face with an average face in 20% steps. Accuracy increased with identity strength and facial age influenced older adults' (but not younger adults') strategy, but there was no evidence of an OAB. Collectively, these results suggest that the OAB depends on task demands and may be absent when searching for one identity. © 2014 The British Psychological Society.

Time Resolved Stereo Particle Image Velocimetry Measurements of the Instabilities Downstream of a Backward-Facing Step in a Swept-Wing Boundary Layer

NASA Technical Reports Server (NTRS)

Eppink, Jenna L.; Yao, Chung-Sheng

2017-01-01

Time-resolved particle image velocimetry (TRPIV) measurements are performed down-stream of a swept backward-facing step, with a height of 49% of the boundary-layer thickness. The results agree well qualitatively with previously reported hotwire measurements, though the amplitudes of the fluctuating components measured using TRPIV are higher. Nonetheless, the low-amplitude instabilities in the flow are fairly well resolved using TR- PIV. Proper orthogonal decomposition is used to study the development of the traveling cross flow and Tollmien-Schlichting (TS) instabilities downstream of the step and to study how they interact to form the large velocity spikes that ultimately lead to transition. A secondary mode within the traveling cross flow frequency band develops with a wavelength close to that of the stationary cross flow instability, so that at a certain point in the phase, it causes an increase in the spanwise modulation initially caused by the stationary cross flow mode. This increased modulation leads to an increase in the amplitude of the TS mode, which, itself, is highly modulated through interactions with the stationary cross flow. When the traveling cross flow and TS modes align in time and space, the large velocity spikes occur. Thus, these three instabilities, which are individually of low amplitude when the spikes start to occur (U'rms/Ue <0.03), interact and combine to cause a large flow disturbance that eventually leads to transition.

Modulation of mechanosensitive calcium-selective cation channels by temperature

NASA Technical Reports Server (NTRS)

Ding, J. P.; Pickard, B. G.

1993-01-01

Gating of associations of mechanosensitive Ca(2+)-selective cation co-channels in the plasmalemma of onion epidermis has a strong and unusual temperature dependence. Tension-dependent activity rises steeply as temperature is lowered from 25 degrees C to about 6 degrees C, but drops to a low level at about 5 degrees C. Under the conditions tested (with Mg2+ and K+ at the cytosolic face of outside-out membrane patches), promotion results both from more bursting at all observed linkage levels and from longer duration of bursts of co-channels linked as quadruplets and quintuplets. Co-channel conductance decreases linearly, but only modestly, with declining temperature. It is proposed that these and related mechanosensitive channels may participate in a variety of responses to temperature, including thermonasty, thermotropism, hydrotropism, and both cold damage and cold acclimation.

An experimental study of combustion: The turbulent structure of a reacting shear layer formed at a rearward-facing step. Ph.D. Thesis. Final Report

NASA Technical Reports Server (NTRS)

Pitz, R. W.

1981-01-01

A premixed propane-air flame is stabilized in a turbulent free shear layer formed at a rearward-facing step. The mean and rms averages of the turbulent velocity flow field were determined by LDV for both reacting and non-reacting flows. The reaching flow was visualized by high speed schlieren photography. Large scale structures dominate the reacting shear layer. The growth of the large scale structures is tied to the propagation of the flame. The linear growth rate of the reacting shear layer defined by the mean velocity profiles is unchanged by combustion but the virtual origin is shifted downstream. The reacting shear layer based on the mean velocity profiles is shifted toward the recirculation zone and the reattachments lengths are shortened by 30%.

8. VIEW OF DAM 83, SHOWING OLD SOURIS RIVER CHANNEL ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

8. VIEW OF DAM 83, SHOWING OLD SOURIS RIVER CHANNEL FROM THE DOWNSTREAM FACE OF THE DAM WITH POND A IN THE BACKGROUND, LOOKING SOUTH - Upper Souris National Wildlife Refuge, Dam 83, Souris River Basin, Foxholm, Surrey (England), ND

Mutual touch during mother-infant face-to-face still-face interactions: influences of interaction period and infant birth status.

PubMed

Mantis, Irene; Stack, Dale M; Ng, Laura; Serbin, Lisa A; Schwartzman, Alex E

2014-08-01

Contact behaviours such as touch, have been shown to be influential channels of nonverbal communication between mothers and infants. While existing research has examined the communicative roles of maternal or infant touch in isolation, mutual touch, whereby touching behaviours occur simultaneously between mothers and their infants, has yet to be examined. The present study was designed to investigate mutual touch during face-to-face interactions between mothers and their 5½-month-old fullterm (n=40), very low birth weight/preterm (VLBW/preterm; n=40) infants, and infants at psychosocial risk (n=41). Objectives were to examine: (1) how the quantitative and qualitative aspects of touch employed by mothers and their infants varied across the normal periods of the still-face (SF) procedure, and (2) how these were associated with risk status. Mutual touch was systematically coded using the mother-infant touch scale. Interactions were found to largely consist of mutual touch and one-sided touch plus movement, highlighting that active touching is pervasive during mother-infant interactions. Consistent with the literature, while the SF period did not negatively affect the amount of mutual touch engaged in for mothers and their fullterm infants and mothers and their infants at psychosocial risk, it did for mothers and their VLBW/preterm infants. Together, results illuminate how both mothers and infants participate in shaping and co-regulating their interactions through the use of touch and underscore the contribution of examining the influence of birth status on mutual touch. Copyright © 2014 Elsevier Inc. All rights reserved.

Computer Assisted Assessment of Face-to-Face Interactions in Health Care Settings

PubMed Central

Ayers, James L.; Haight, Stewart A.

1981-01-01

In this paper, the development of an objective procedure for the empirical assessment of dyadic face-to-face interactions is presented. This procedure, called the Interpersonal Tracking Task (ITT) permits two persons who have just finished video taping their conversation to watch themselves immediately after and, while viewing themselves, answer a sequence of questions systematically presented on a second monitor by a microcomputer. Immediately after viewing their tape, each participant can receive feedback in the form of descriptive statistics summarizing their responses to specific questions and a series of colored bar graphs by which they can view change in their responses over the course of their interaction. The unique role of a computer in this assessment is discussed together with specific components of the software. Preliminary research with the ITT in health care settings has suggested steps for its further development as a research instrument and learning tool whereby individuals might more closely examine their dealings with each other. ImagesFigure 1

VIEW OF WEST SIDE OF PAULINE KILKER HOUSE, SHOWING STEPS ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

VIEW OF WEST SIDE OF PAULINE KILKER HOUSE, SHOWING STEPS TO REAR DOOR AND TO BASEMENT, FACING SOUTHEAST. - Pauline Kilker House, 1410 North Lincoln Avenue-3300 West Laurel Street, Tampa, Hillsborough County, FL

Fast Face-Recognition Optical Parallel Correlator Using High Accuracy Correlation Filter

NASA Astrophysics Data System (ADS)

Watanabe, Eriko; Kodate, Kashiko

2005-11-01

We designed and fabricated a fully automatic fast face recognition optical parallel correlator [E. Watanabe and K. Kodate: Appl. Opt. 44 (2005) 5666] based on the VanderLugt principle. The implementation of an as-yet unattained ultra high-speed system was aided by reconfiguring the system to make it suitable for easier parallel processing, as well as by composing a higher accuracy correlation filter and high-speed ferroelectric liquid crystal-spatial light modulator (FLC-SLM). In running trial experiments using this system (dubbed FARCO), we succeeded in acquiring remarkably low error rates of 1.3% for false match rate (FMR) and 2.6% for false non-match rate (FNMR). Given the results of our experiments, the aim of this paper is to examine methods of designing correlation filters and arranging database image arrays for even faster parallel correlation, underlining the issues of calculation technique, quantization bit rate, pixel size and shift from optical axis. The correlation filter has proved its excellent performance and higher precision than classical correlation and joint transform correlator (JTC). Moreover, arrangement of multi-object reference images leads to 10-channel correlation signals, as sharply marked as those of a single channel. This experiment result demonstrates great potential for achieving the process speed of 10000 face/s.

Study on Strata Behavior Regularity of 1301 Face in Thick Bedrock of Wei - qiang Coal Mine

NASA Astrophysics Data System (ADS)

Gu, Shuancheng; Yao, Boyu

2017-09-01

In order to ensure the safe and efficient production of the thick bedrock face, the rule of the strata behavior of the thick bedrock face is discussed through the observation of the strata pressure of the 1301 first mining face in Wei qiang coal mine. The initial face is to press the average distance of 50.75m, the periodic weighting is to press the average distance of 12.1m; during the normal mining period, although the upper roof can not be broken at the same time, but the pressure step is basically the same; the working face for the first weighting and periodical weighting is more obvious to the change of pressure step change, when the pressure of the working face is coming, the stent force increased significantly, but there are still part of the stent work resistance exceeds the rated working resistance, low stability, still need to strengthen management.

Pose invariant face recognition: 3D model from single photo

NASA Astrophysics Data System (ADS)

Napoléon, Thibault; Alfalou, Ayman

2017-02-01

Face recognition is widely studied in the literature for its possibilities in surveillance and security. In this paper, we report a novel algorithm for the identification task. This technique is based on an optimized 3D modeling allowing to reconstruct faces in different poses from a limited number of references (i.e. one image by class/person). Particularly, we propose to use an active shape model to detect a set of keypoints on the face necessary to deform our synthetic model with our optimized finite element method. Indeed, in order to improve our deformation, we propose a regularization by distances on graph. To perform the identification we use the VanderLugt correlator well know to effectively address this task. On the other hand we add a difference of Gaussian filtering step to highlight the edges and a description step based on the local binary patterns. The experiments are performed on the PHPID database enhanced with our 3D reconstructed faces of each person with an azimuth and an elevation ranging from -30° to +30°. The obtained results prove the robustness of our new method with 88.76% of good identification when the classic 2D approach (based on the VLC) obtains just 44.97%.

The human red cell voltage-regulated cation channel. The interplay with the chloride conductance, the Ca(2+)-activated K(+) channel and the Ca(2+) pump.

PubMed

Bennekou, P; Kristensen, B I; Christophersen, P

2003-09-01

The activation/deactivation kinetics of the human erythrocyte voltage-dependent cation channel was characterized at the single-channel level using inside-out patches. It was found that the time dependence for voltage activation after steps to positive membrane potentials was slow ( t(1/2) about 30 s), whereas the deactivation was fast ( t(1/2) about 15 ms). Both activation and deactivation of this channel were also demonstrated in intact red cells in suspension. At very positive membrane potentials generated by suspension in extracellular low Cl(-) concentrations, the cation conductance switched on with a time constant of about 2 min. Deactivation of the cation channel was clearly demonstrated during transient activation of the Gárdos channel elicited by Ca(2+) influx via the cation channel and ensuing efflux via the Ca(2+) pump. Thus, the voltage-dependent cation channel, the Gárdos channel and the Ca(2+) pump constitute a coupled feedback-regulated system that may become operative under physiological conditions.

Protein patterning in polycarbonate microfluidic channels

NASA Astrophysics Data System (ADS)

Thomson, David A.; Hayes, Jason P.; Thissen, Helmut

2004-03-01

In this work protein patterning has been achieved within a polycarbonate microfluidic device. Channel structures were first coated with plasma polymerized allylamine (ALAPP) followed by the "cloud point" deposition of polyethylene oxide (PEO), a protein repellent molecule. Excimer laser micromachining was used to pattern the PEO to control protein localization. Subsequent removal of a sacrificial layer of polycarbonate resulted in the patterned polymer coating only in the channels of a simple fluidic device. Following a final diffusion bonding fabrication step the devices were filled with a buffer containing Streptavidin conjugated with fluorescein, and visualized under a confocal fluorescent microscope. This confirmed that protein adhesion occurred only in laser patterned areas. The ability to control protein adhesion in microfludic channels leads to the possibility of generating arrays of proteins or cells within polymer microfludics for cheap automated biosensors and synthesis systems.

Unsteady Crystal Growth Due to Step-Bunch Cascading

NASA Technical Reports Server (NTRS)

Vekilov, Peter G.; Lin, Hong; Rosenberger, Franz

1997-01-01

Based on our experimental findings of growth rate fluctuations during the crystallization of the protein lysozym, we have developed a numerical model that combines diffusion in the bulk of a solution with diffusive transport to microscopic growth steps that propagate on a finite crystal facet. Nonlinearities in layer growth kinetics arising from step interaction by bulk and surface diffusion, and from step generation by surface nucleation, are taken into account. On evaluation of the model with properties characteristic for the solute transport, and the generation and propagation of steps in the lysozyme system, growth rate fluctuations of the same magnitude and characteristic time, as in the experiments, are obtained. The fluctuation time scale is large compared to that of step generation. Variations of the governing parameters of the model reveal that both the nonlinearity in step kinetics and mixed transport-kinetics control of the crystallization process are necessary conditions for the fluctuations. On a microscopic scale, the fluctuations are associated with a morphological instability of the vicinal face, in which a step bunch triggers a cascade of new step bunches through the microscopic interfacial supersaturation distribution.

Gasotransmitter Regulation of Ion Channels: A Key Step in O2 Sensing By the Carotid Body

PubMed Central

Prabhakar, Nanduri R.

2014-01-01

Carotid bodies detect hypoxia in arterial blood, translating this stimulus into physiological responses via the CNS. It is long established that ion channels are critical to this process. More recent evidence indicates that gasotransmitters exert powerful influences on O2 sensing by the carotid body. Here, we review current understanding of hypoxia-dependent production of gasotransmitters, how they regulate ion channels in the carotid body, and how this impacts carotid body function. PMID:24382871

Channeling of multikilojoule high-intensity laser beams in an inhomogeneous plasma

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ivancic, S.; Haberberger, D.; Habara, H.

Channeling experiments were performed that demonstrate the transport of high-intensity (>10¹⁸ W/cm²), multikilojoule laser light through a millimeter-sized, inhomogeneous (~300-μm density scale length) laser produced plasma up to overcritical density, which is an important step forward for the fast-ignition concept. The background plasma density and the density depression inside the channel were characterized with a novel optical probe system. The channel progression velocity was measured, which agrees well with theoretical predictions based on large scale particle-in-cell simulations, confirming scaling laws for the required channeling laser energy and laser pulse duration, which are important parameters for future integrated fast-ignition channeling experiments.

``Just Another Distribution Channel?''

NASA Astrophysics Data System (ADS)

Lemstra, Wolter; de Leeuw, Gerd-Jan; van de Kar, Els; Brand, Paul

The telecommunications-centric business model of mobile operators is under attack due to technological convergence in the communication and content industries. This has resulted in a plethora of academic contributions on the design of new business models and service platform architectures. However, a discussion of the challenges that operators are facing in adopting these models is lacking. We assess these challenges by considering the mobile network as part of the value system of the content industry. We will argue that from the perspective of a content provider the mobile network is ‘just another’ distribution channel. Strategic options available for the mobile communication operators are to deliver an excellent distribution channel for content delivery or to move upwards in the value chain by becoming a content aggregator. To become a mobile content aggregator operators will have to develop or acquire complementary resources and capabilities. Whether this strategic option is sustainable remains open.

Investigation of the capillary flow through open surface microfluidic structures

NASA Astrophysics Data System (ADS)

Taher, Ahmed; Jones, Benjamin; Fiorini, Paolo; Lagae, Liesbet

2017-02-01

The passive nature of capillary microfluidics for pumping and actuation of fluids is attractive for many applications including point of care medical diagnostics. For such applications, there is often the need to spot dried chemical reagents in the bottom of microfluidic channels after device fabrication; it is often more practical to have open surface devices (i.e., without a cover or lid). However, the dynamics of capillary driven flow in open surface devices have not been well studied for many geometries of interest. In this paper, we investigate capillary flow in an open surface microchannel with a backward facing step. An analytical model is developed to calculate the capillary pressure as the liquid-vapor interface traverses a backward facing step in an open microchannel. The developed model is validated against results from Surface Evolver liquid-vapor surface simulations and ANSYS Fluent two-phase flow simulations using the volume of fluid approach. Three different aspect ratios (inlet channel height by channel width) were studied. The analytical model shows good agreement with the simulation results from both modeling methods for all geometries. The analytical model is used to derive an expression for the critical aspect ratio (the minimum channel aspect ratio for flow to proceed across the backward facing step) as a function of contact angle.

3D Face Modeling Using the Multi-Deformable Method

PubMed Central

Hwang, Jinkyu; Yu, Sunjin; Kim, Joongrock; Lee, Sangyoun

2012-01-01

In this paper, we focus on the problem of the accuracy performance of 3D face modeling techniques using corresponding features in multiple views, which is quite sensitive to feature extraction errors. To solve the problem, we adopt a statistical model-based 3D face modeling approach in a mirror system consisting of two mirrors and a camera. The overall procedure of our 3D facial modeling method has two primary steps: 3D facial shape estimation using a multiple 3D face deformable model and texture mapping using seamless cloning that is a type of gradient-domain blending. To evaluate our method's performance, we generate 3D faces of 30 individuals and then carry out two tests: accuracy test and robustness test. Our method shows not only highly accurate 3D face shape results when compared with the ground truth, but also robustness to feature extraction errors. Moreover, 3D face rendering results intuitively show that our method is more robust to feature extraction errors than other 3D face modeling methods. An additional contribution of our method is that a wide range of face textures can be acquired by the mirror system. By using this texture map, we generate realistic 3D face for individuals at the end of the paper. PMID:23201976

III-nitrides on oxygen- and zinc-face ZnO substrates

NASA Astrophysics Data System (ADS)

Namkoong, Gon; Burnham, Shawn; Lee, Kyoung-Keun; Trybus, Elaissa; Doolittle, W. Alan; Losurdo, Maria; Capezzuto, Pio; Bruno, Giovanni; Nemeth, Bill; Nause, Jeff

2005-10-01

The characteristics of III-nitrides grown on zinc- and oxygen-face ZnO by plasma-assisted molecular beam epitaxy were investigated. The reflection high-energy electron diffraction pattern indicates formation of a cubic phase at the interface between III-nitride and both Zn- and O-face ZnO. The polarity indicates that Zn-face ZnO leads to a single polarity, while O-face ZnO forms mixed polarity of III-nitrides. Furthermore, by using a vicinal ZnO substrate, the terrace-step growth of GaN was realized with a reduction by two orders of magnitude in the dislocation-related etch pit density to ˜108cm-2, while a dislocation density of ˜1010cm-2 was obtained on the on-axis ZnO substrates.

Simplification and analysis of models of calcium dynamics based on IP3-sensitive calcium channel kinetics.

PubMed

Tang, Y; Stephenson, J L; Othmer, H G

1996-01-01

We study the models for calcium (Ca) dynamics developed in earlier studies, in each of which the key component is the kinetics of intracellular inositol-1,4,5-trisphosphate-sensitive Ca channels. After rapidly equilibrating steps are eliminated, the channel kinetics in these models are represented by a single differential equation that is linear in the state of the channel. In the reduced kinetic model, the graph of the steady-state fraction of conducting channels as a function of log10(Ca) is a bell-shaped curve. Dynamically, a step increase in inositol-1,4,5-trisphosphate induces an incremental increase in the fraction of conducting channels, whereas a step increase in Ca can either potentiate or inhibit channel activation, depending on the Ca level before and after the increase. The relationships among these models are discussed, and experimental tests to distinguish between them are given. Under certain conditions the models for intracellular calcium dynamics are reduced to the singular perturbed form epsilon dx/d tau = f(x, y, p), dy/d tau = g(x, y, p). Phase-plane analysis is applied to a generic form of these simplified models to show how different types of Ca response, such as excitability, oscillations, and a sustained elevation of Ca, can arise. The generic model can also be used to study frequency encoding of hormonal stimuli, to determine the conditions for stable traveling Ca waves, and to understand the effect of channel properties on the wave speed.

Detail of concrete pillars and steps leading to main entry ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Detail of concrete pillars and steps leading to main entry at southeast elevation; camera facing west. - Mare Island Naval Shipyard, Hospital Ward, Johnson Lane, west side at intersection of Johnson Lane & Cossey Street, Vallejo, Solano County, CA

Substrate channel in nitrogenase revealed by a molecular dynamics approach.

PubMed

Smith, Dayle; Danyal, Karamatullah; Raugei, Simone; Seefeldt, Lance C

2014-04-15

Mo-dependent nitrogenase catalyzes the biological reduction of N2 to two NH3 molecules at FeMo-cofactor buried deep inside the MoFe protein. Access of substrates, such as N2, to the active site is likely restricted by the surrounding protein, requiring substrate channels that lead from the surface to the active site. Earlier studies on crystallographic structures of the MoFe protein have suggested three putative substrate channels. Here, we have utilized submicrosecond atomistic molecular dynamics simulations to allow the nitrogenase MoFe protein to explore its conformational space in an aqueous solution at physiological ionic strength, revealing a putative substrate channel. The viability of this observed channel was tested by examining the free energy of passage of N2 from the surface through the channel to FeMo-cofactor, resulting in the discovery of a very low energy barrier. These studies point to a viable substrate channel in nitrogenase that appears during thermal motions of the protein in an aqueous environment and that approaches a face of FeMo-cofactor earlier implicated in substrate binding.

Metasurface for multi-channel terahertz beam splitters and polarization rotators

NASA Astrophysics Data System (ADS)

Zang, XiaoFei; Gong, HanHong; Li, Zhen; Xie, JingYa; Cheng, QingQing; Chen, Lin; Shkurinov, Alexander P.; Zhu, YiMing; Zhuang, SongLin

2018-04-01

Terahertz beam splitters and polarization rotators are two typical devices with wide applications ranging from terahertz communication to system integration. However, they are faced with severe challenges in manipulating THz waves in multiple channels, which is desirable for system integration and device miniaturization. Here, we propose a method to design ultra-thin multi-channel THz beam splitters and polarization rotators simultaneously. The reflected beams are divided into four beams with nearly the same density under illumination of linear-polarized THz waves, while the polarization of reflected beams in each channel is modulated with a rotation angle or invariable with respect to the incident THz waves, leading to the multi-channel polarization rotator (multiple polarization rotation in the reflective channels) and beam splitter, respectively. Reflective metasurfaces, created by patterning metal-rods with different orientations on a polyimide film, were fabricated and measured to demonstrate these characteristics. The proposed approach provides an efficient way of controlling polarization of THz waves in various channels, which significantly simplifies THz functional devices and the experimental system.

The human role in changing river channels

NASA Astrophysics Data System (ADS)

Gregory, K. J.

2006-09-01

Direct consequences of the human role, where human activity affects river channels through engineering works including channelization, dam construction, diversion and culverting, have been long recognised [Marsh, G.P., 1864. Man and Nature or Physical Geography as Modified by Human Action. Charles Scribner, New York; Thomas Jr., W.L., (ed.) 1956. Man's Role in Changing the Face of the Earth. Chicago, University of Chicago Press, Chicago.]. The less obvious indirect effects of point and reach changes occurring downstream and throughout the basin, however, are much more recently appreciated, dating from key contributions by Strahler [Strahler, A.N., 1956. The nature of induced erosion and aggradation. In W. L. Thomas (Ed.), Man's Role in Changing the Face of the Earth. University of Chicago Press, Chicago, 621-638.], Wolman [Wolman, M.G., 1967. A cycle of sedimentation and erosion in urban river channels. Geografiska Annaler 49A, 385-95.], Schumm [Schumm, S.A., 1969. River metamorphosis. Proceedings American Society of Civil Engineers, Journal Hydraulics Division 95, 255-73.], and Graf [Graf, W.L., 1977. The rate law in fluvial geomorphology. American Journal of Science, 277, 178-191.]. These are complemented by effects of alterations of land use, such as deforestation, intensive agriculture and incidence of fire, with the most extreme effects produced by building activity and urbanisation. Changing river channels are most evident in the channel cross-section where changes of size, shape and composition are now well-established, with up to tenfold increases or decreases illustrated by results from more than 200 world studies. In addition the overall channel planform, the network and the ecology have changed. Specific terms have become associated with changing river channels including enlargement, shrinkage and metamorphosis. Although the scope of adjustment has been established, it has not always been possible to predict what will happen in a particular location

Dissipating Step Bunches during Crystallization under Transport Control

NASA Technical Reports Server (NTRS)

Lin, Hong; Yau, S.-T.; Vekilov, Peter, G.

2003-01-01

In studies of crystal formation by the generation and spreading of layers, equidistant step trains are considered unstable---bunches and other spatiotemporal patterns of the growth steps are viewed as ubiquitous. We provide an example to the opposite. We monitor the spatiotemporal dynamics of steps and the resulting step patterns during crystallization of the proteins ferritin and apoferritin using the atomic force microscope. The variations in step velocity and density are not correlated, indicating the lack of a long-range attraction between the steps. We show that (i) because of its coupling to bulk transport, nucleation of new layers is chaotic and occurs at the facet edges, where the interfacial supersaturation is higher; (ii) step bunches self-organize via the competition for supply from the solution; and, (iii) bunches of weakly interacting steps decay as they move along the face. Tests by numerical modeling support the conclusions about the mechanisms underlying our observations. The results from these systems suggest that during crystallization controlled by transport, with weakly or noninteracting growth steps, the stable kinetic state of the surface is an equidistant step train, and step bunches only arise during nucleation of new layers. Since nucleation only occurs at a few sites on the surface, the surface morphology may be controllably patterned or smoothened by locally controlling nucleation.

Face antispoofing based on frame difference and multilevel representation

NASA Astrophysics Data System (ADS)

Benlamoudi, Azeddine; Aiadi, Kamal Eddine; Ouafi, Abdelkrim; Samai, Djamel; Oussalah, Mourad

2017-07-01

Due to advances in technology, today's biometric systems become vulnerable to spoof attacks made by fake faces. These attacks occur when an intruder attempts to fool an established face-based recognition system by presenting a fake face (e.g., print photo or replay attacks) in front of the camera instead of the intruder's genuine face. For this purpose, face antispoofing has become a hot topic in face analysis literature, where several applications with antispoofing task have emerged recently. We propose a solution for distinguishing between real faces and fake ones. Our approach is based on extracting features from the difference between successive frames instead of individual frames. We also used a multilevel representation that divides the frame difference into multiple multiblocks. Different texture descriptors (local binary patterns, local phase quantization, and binarized statistical image features) have then been applied to each block. After the feature extraction step, a Fisher score is applied to sort the features in ascending order according to the associated weights. Finally, a support vector machine is used to differentiate between real and fake faces. We tested our approach on three publicly available databases: CASIA Face Antispoofing database, Replay-Attack database, and MSU Mobile Face Spoofing database. The proposed approach outperforms the other state-of-the-art methods in different media and quality metrics.

Hall effect mobility for SiC MOSFETs with increasing dose of nitrogen implantation into channel region

NASA Astrophysics Data System (ADS)

Noguchi, Munetaka; Iwamatsu, Toshiaki; Amishiro, Hiroyuki; Watanabe, Hiroshi; Kita, Koji; Yamakawa, Satoshi

2018-04-01

The Hall effect mobility (μHall) of the Si-face 4H-SiC metal–oxide–semiconductor field effect transistor (MOSFET) with a nitrogen (N)-implanted channel region was investigated by increasing the N dose. The μHall in the channel region was systematically examined regarding channel structures, that is, the surface and buried channels. It was experimentally demonstrated that increasing the N dose results in an improvement in μHall in the channel region due to the formation of the buried channel. However, further increase in N dose was found to decrease the μHall in the channel region, owing to the decrease in the electron mobility in the N-implanted bulk region.

A 15-Step Synthesis of (+)-Ryanodol

PubMed Central

Chuang, Kangway V.; Xu, Chen; Reisman, Sarah E.

2017-01-01

(+)-Ryanodine and (+)-ryanodol are complex diterpenoids that modulate intracellular Ca2+ release at ryanodine receptors, ion channels critical for skeletal and cardiac muscle excitation–contraction coupling and synaptic transmission. Chemical derivatization of these diterpenoids has demonstrated that certain peripheral structural modifications can alter binding affinity and selectivity among ryanodine receptor isoforms. Here we report a short chemical synthesis of (+)-ryanodol that proceeds in only 15 steps from the commercially available terpene (S)-pulegone. The efficiency of the synthesis derives from the use of a Pauson-Khand reaction to rapidly build the carbon framework, and a remarkable SeO2-mediated oxidation to install three oxygen atoms in single step. This work highlights how strategic C–O bond constructions can streamline the synthesis of poly-hydroxylated terpenes by minimizing protecting group and redox adjustments. PMID:27563092

A comparative study of one-step and two-step approaches for MAPbI3 perovskite layer and its influence on the performance of mesoscopic perovskite solar cell

NASA Astrophysics Data System (ADS)

Wang, Minhuan; Feng, Yulin; Bian, Jiming; Liu, Hongzhu; Shi, Yantao

2018-01-01

The mesoscopic perovskite solar cells (M-PSCs) were synthesized with MAPbI3 perovskite layers as light harvesters, which were grown with one-step and two-step solution process, respectively. A comparative study was performed through the quantitative correlation of resulting device performance and the crystalline quality of perovskite layers. Comparing with the one-step counterpart, a pronounced improvement in the steady-state power conversion efficiencies (PCEs) by 56.86% was achieved with two-step process, which was mainly resulted from the significant enhancement in fill factor (FF) from 48% to 77% without sacrificing the open circuit voltage (Voc) and short circuit current (Jsc). The enhanced FF was attributed to the reduced non-radiative recombination channels due to the better crystalline quality and larger grain size with the two-step processed perovskite layer. Moreover, the superiority of two-step over one-step process was demonstrated with rather good reproducibility.

A Self-Determination Perspective on Online Health Information Seeking: The Internet vs. Face-to-Face Office Visits With Physicians.

PubMed

Lee, Seow Ting; Lin, Julian

2016-06-01

This study elucidates the experiential and motivational aspects of online health information beyond the theoretically limited instrumental perspective that dominates the extant literature. Based on a sample of 993 online health information seekers in India, the survey found that online health information seeking offers individuals greater autonomy, competence, and relatedness compared to face-to-face office visits with physicians. According to self-determination theory, individuals are motivated to act by a sense of volition and experience of willingness, validation of one's skills and competencies, and feeling of connection with others who shaped one's decisions. These 3 psychological needs, which motivate individuals to pursue what they innately seek as human beings, help explain why individuals turn online for health information. T tests showed that all 3 self-determination theory constructs -autonomy, competence, and relatedness-were higher for online health information seeking than for face-to-face office visits with physicians. A regression analysis found that 2 variables, autonomy and relatedness, explained online health information seeking. Competence was not a significant factor, likely because of competency issues faced by individuals in interpreting, understanding, and making use of online health information. The findings, which do not suggest that online health information seeking would displace physicians as many have feared, offer promise for an integrated system of care. Office visits with physicians would necessarily evolve into an expanded communicative space of health information seeking instead of an alternative channel for health information.

Hispanic women's preferences for breast health information: subjective cultural influences on source, message, and channel.

PubMed

Oetzel, John; De Vargas, Felicia; Ginossar, Tamar; Sanchez, Christina

2007-01-01

The purpose of this study was to investigate the influence of 3 subjective cultural variables--self-construals (independence and interdependence), ethnic identity (bicultural, assimilation, traditional, and marginal), and cultural health attributions (equity and behavioral-environmental attributions)--on source, message, and channel preferences for receiving breast health information by Hispanic women age 35 or older. Subjective cultural variables collectively accounted for 2% to 28% of the variance in communication preferences. In addition, several associations were discovered: (a) having an interdependent self-construal was associated positively with preferences for significant other as a source, family sources, fear messages, media channels, and face-to-face channels; (b) having a bicultural identity was associated positively with preferences for family sources and media channels, but negatively with a desire for no information; and (c) having a marginal identity and equity attributions were associated positively with preferences for fear messages and a desire for no information, but negatively with preferences for expert sources. These findings are discussed in the context of tailoring breast health information to Hispanic women using computer technology and entertainment-education.

[Study of changes in Chinese herbal medicine distribution channel].

PubMed

Lv, Hua; Yang, Guang; Huang, Lu-Qi

2014-07-01

Distribution channel of Chinese herbal medicines has been changing. From Han to Ming Dynasty, Chinese herbal medicine were mainly trafficked to urban by dealers or farmers; From the Ming Dynasty to the foundation of new China, distribution channels are primarily intermediated with township "bazaar" and national distribution center with fixed place and regularly trading hours. In the planned economy period, the state-owned herbal medicine company was the sole medium with monopoly nature. From the mid1980s to the end of last century, planned economy and market economy have been co-existing. Stepping into 21st century, producing area highlighted in the distribution channels. Presence or absence and rise or fall of different types of distribution market went throughout the changing process of distribution channels, which became an important clue. Changes were motivated by economical consideration of channel subject, which originated from commodity characteristic and social environment changes.

Fine sediment in pools: An index of how sediment is affecting a stream channel

Treesearch

Tom Lisle; Sue Hilton

1991-01-01

One of the basic issues facing managers of fisheries watersheds is how inputs of sediment affect stream channels. In some cases we can measure and even roughly predict effects of land use on erosion and delivery of sediment from hillslopes to streams. But we are at a loss about how a given increase in sediment load will affect channel morphology, flow conditions, and...

Laboratory Modelling of the Effect of Bend Orientation on the Morphological Development of Alluvial Channels

NASA Astrophysics Data System (ADS)

Good, R. G. R.; Sullivan, C.; Binns, A. D.

2017-12-01

Bend orientation, or skewness, in natural streams is often caused by riparian vegetation or underlying geology that lead to a meandering stream following a non-sinuous path. The bend orientation affects how the fluid momentum interacts with the bed and banks, which can alter the location and shape of bedforms as well as the channel planform geometry. An experimental study in a laboratory sand flume with movable bed and banks (5.6 m long, 1.9 m wide; D50 = 0.7 mm; B = 0.2m; 3 wavelengths) was carried out to quantify the effect of bend orientation on bedform development and planform changes. While previous research in the literature has found that channels with an upstream bend orientation had a less developed secondary flow than a downstream orientation, few studies on the morphological development of streams having varying bend orientation have been conducted. In total, three runs were carried out using channels with upstream, downstream, and no skewness. The runs progressed in a series of time-steps to monitor the morphological evolution of the streams with time. Sediment transport rates were quantified at the outlet, flow was measured using an ultrasonic flow meter at the inlet, flow depths were measured at the apex of the bends, and channel morphology was measured at each time step using Structure-from-Motion photogrammetry with Agisoft Photoscan. Bend orientation was found to influence the position of the point bar development as well as the locations of maximum and minimum channel migration. Relative to the bend apex, point bars tended to be positioned in the same direction as the channel skewness. Channel width showed the greatest variation with the upstream orientation, with the channel narrowing before the apex where the channel flows in the up-valley direction, and widening downstream of the apex. These results show that the channel orientation influences the morphological development of the channel bed and banks. The effect of velocity structure and

Premature Mobility of Boulders in Constructed Step-pool River Structures in the Carmel River, CA: The Role of Fish-centric Design Constraints, and Flow on Structural Stability

NASA Astrophysics Data System (ADS)

Smith, D. P.; Chow, K.; Luna, L.

2017-12-01

The 32 m tall San Clemente Dam (Carmel River, CA) was removed in 2015 to eliminate seismic risk and to improve fish passage for all life stages of steelhead (O. mykiss). Reservoir sediment was sequestered in place, rather than released, and a new 1000 m long channel/floodplain system was constructed to circumvent the stored sediment. The channel comprised a 250 m long, meandering low-gradient reach and a 750 m reach with alternating step-pool sections, plane beds, and resting pools. The floodprone surfaces were compacted, wrapped in geotechnical fabric and vegetated. This study analyzes the geomorphic evolution of the new channel system during its first two years of service based upon detailed field inspection, SfM photogrammetry, orthophoto analysis, and 2d hydraulic modeling. A significant proportion of the step-pool structures experienced premature mobility and several reaches of engineered stream banks were eroded in the first year. Individual, six-tonne boulders were mobilized despite experiencing less than the 3 yr flow. The channel and floodplain were fully repaired following the first year. Strong flows (two 10-yr floods and a 30-yr flood) during the second year catastrophically altered the constructed channel and floodplain. While the low-gradient reach remained intact, each of the original step-pool structures was either completely mobilized and destroyed, buried by gravel, or bypassed by the subsequent channel. Despite the overall structural failure of the constructed channel, the new channel does not block steelhead migration, and can be serendipitously considered an ecological success. Step-pool design was constrained by a fish-centric requirement that steps be 1 ft tall or less. Some constructed "resting pools" filled rather than transport sediment. Using fish-centric constraints in the design, rather than strictly fluvial geomorphic principles may have contributed to early failure of the step-pool structures and other parts of the system.

Growth from Solutions: Kink dynamics, Stoichiometry, Face Kinetics and stability in turbulent flow

NASA Technical Reports Server (NTRS)

Chernov, A. A.; DeYoreo, J. J.; Rashkovich, L. N.; Vekilov, P. G.

2005-01-01

1. Kink dynamics. The first segment of a polygomized dislocation spiral step measured by AFM demonstrates up to 60% scattering in the critical length l*- the length when the segment starts to propagate. On orthorhombic lysozyme, this length is shorter than that the observed interkink distance. Step energy from the critical segment length based on the Gibbs-Thomson law (GTL), l* = 20(omega)alpha/(Delta)mu is several times larger than the energy from 2D nucleation rate. Here o is tine building block specific voiume, a is the step riser specific free energy, Delta(mu) is the crystallization driving force. These new data support our earlier assumption that the classical Frenkel, Burton -Cabrera-Frank concept of the abundant kink supply by fluctuations is not applicable for strongly polygonized steps. Step rate measurements on brushite confirms that statement. This is the1D nucleation of kinks that control step propagation. The GTL is valid only if l* step and face rates of a non-Kossel complex molecular monocomponent or any binary, AB, lattice was found theoretically to be proportional to 1/(zeta(sup 1/2) + zeta(sup - 1/2)), where zeta = [B]/[A] is the stoichiometry ratio in solution. The velocities reach maxima at zeta = 1. AFM studies of step rates on CaOxalate monohydrate (kidney stones) from aqueous solution was found to obey the law mentioned above. Generalization for more complex lattice will be discussed. 3. Turbulence. In agreement with theory, high precision in-situ laser interferometry of the (101) KDP crystal face shows step

Ion flux through membrane channels--an enhanced algorithm for the Poisson-Nernst-Planck model.

PubMed

Dyrka, Witold; Augousti, Andy T; Kotulska, Malgorzata

2008-09-01

A novel algorithmic scheme for numerical solution of the 3D Poisson-Nernst-Planck model is proposed. The algorithmic improvements are universal and independent of the detailed physical model. They include three major steps: an adjustable gradient-based step value, an adjustable relaxation coefficient, and an optimized segmentation of the modeled space. The enhanced algorithm significantly accelerates the speed of computation and reduces the computational demands. The theoretical model was tested on a regular artificial channel and validated on a real protein channel-alpha-hemolysin, proving its efficiency. (c) 2008 Wiley Periodicals, Inc.

A multibiometric face recognition fusion framework with template protection

NASA Astrophysics Data System (ADS)

Chindaro, S.; Deravi, F.; Zhou, Z.; Ng, M. W. R.; Castro Neves, M.; Zhou, X.; Kelkboom, E.

2010-04-01

In this work we present a multibiometric face recognition framework based on combining information from 2D with 3D facial features. The 3D biometrics channel is protected by a privacy enhancing technology, which uses error correcting codes and cryptographic primitives to safeguard the privacy of the users of the biometric system at the same time enabling accurate matching through fusion with 2D. Experiments are conducted to compare the matching performance of such multibiometric systems with the individual biometric channels working alone and with unprotected multibiometric systems. The results show that the proposed hybrid system incorporating template protection, match and in some cases exceed the performance of corresponding unprotected equivalents, in addition to offering the additional privacy protection.

Individual differences in perceiving and recognizing faces-One element of social cognition.

PubMed

Wilhelm, Oliver; Herzmann, Grit; Kunina, Olga; Danthiir, Vanessa; Schacht, Annekathrin; Sommer, Werner

2010-09-01

Recognizing faces swiftly and accurately is of paramount importance to humans as a social species. Individual differences in the ability to perform these tasks may therefore reflect important aspects of social or emotional intelligence. Although functional models of face cognition based on group and single case studies postulate multiple component processes, little is known about the ability structure underlying individual differences in face cognition. In 2 large individual differences experiments (N = 151 and N = 209), a broad variety of face-cognition tasks were tested and the component abilities of face cognition-face perception, face memory, and the speed of face cognition-were identified and then replicated. Experiment 2 also showed that the 3 face-cognition abilities are clearly distinct from immediate and delayed memory, mental speed, general cognitive ability, and object cognition. These results converge with functional and neuroanatomical models of face cognition by demonstrating the difference between face perception and face memory. The results also underline the importance of distinguishing between speed and accuracy of face cognition. Together our results provide a first step toward establishing face-processing abilities as an independent ability reflecting elements of social intelligence. (PsycINFO Database Record (c) 2010 APA, all rights reserved).

The cooperative voltage sensor motion that gates a potassium channel.

PubMed

Pathak, Medha; Kurtz, Lisa; Tombola, Francesco; Isacoff, Ehud

2005-01-01

The four arginine-rich S4 helices of a voltage-gated channel move outward through the membrane in response to depolarization, opening and closing gates to generate a transient ionic current. Coupling of voltage sensing to gating was originally thought to operate with the S4s moving independently from an inward/resting to an outward/activated conformation, so that when all four S4s are activated, the gates are driven to open or closed. However, S4 has also been found to influence the cooperative opening step (Smith-Maxwell et al., 1998a), suggesting a more complex mechanism of coupling. Using fluorescence to monitor structural rearrangements in a Shaker channel mutant, the ILT channel (Ledwell and Aldrich, 1999), that energetically isolates the steps of activation from the cooperative opening step, we find that opening is accompanied by a previously unknown and cooperative movement of S4. This gating motion of S4 appears to be coupled to the internal S6 gate and to two forms of slow inactivation. Our results suggest that S4 plays a direct role in gating. While large transmembrane rearrangements of S4 may be required to unlock the gating machinery, as proposed before, it appears to be the gating motion of S4 that drives the gates to open and close.

The Cooperative Voltage Sensor Motion that Gates a Potassium Channel

PubMed Central

Pathak, Medha; Kurtz, Lisa; Tombola, Francesco; Isacoff, Ehud

2005-01-01

The four arginine-rich S4 helices of a voltage-gated channel move outward through the membrane in response to depolarization, opening and closing gates to generate a transient ionic current. Coupling of voltage sensing to gating was originally thought to operate with the S4s moving independently from an inward/resting to an outward/activated conformation, so that when all four S4s are activated, the gates are driven to open or closed. However, S4 has also been found to influence the cooperative opening step (Smith-Maxwell et al., 1998a), suggesting a more complex mechanism of coupling. Using fluorescence to monitor structural rearrangements in a Shaker channel mutant, the ILT channel (Ledwell and Aldrich, 1999), that energetically isolates the steps of activation from the cooperative opening step, we find that opening is accompanied by a previously unknown and cooperative movement of S4. This gating motion of S4 appears to be coupled to the internal S6 gate and to two forms of slow inactivation. Our results suggest that S4 plays a direct role in gating. While large transmembrane rearrangements of S4 may be required to unlock the gating machinery, as proposed before, it appears to be the gating motion of S4 that drives the gates to open and close. PMID:15623895

Comparison of morphology of active cyclic steps created by turbidity currents on Squamish Delta, British Columbia, Canada with flume experiments

NASA Astrophysics Data System (ADS)

Yokokawa, Miwa; Yamamoto, Shinya; Higuchi, Hiroyuki; Hughes Clarke, John E.; Izumi, Norihiro

2015-04-01

Upper-flow-regime bedforms, such as cyclic steps and antidunes, have been reported to be formed by turbidity currents. Their formative conditions are, however, not fully understood because of the difficulty of field surveys in the deep sea. Field observations of turbidity currents and seabed topography on the Squamish delta in Howe Sound, British Columbia, Canada have been undertaken which found bedwaves actively migrating in the upstream direction in channels formed on the prodelta slope. Their topography and behavior suggest that they are cyclic steps formed by turbidity currents. Because Squamish delta is as shallow as around 150 m, and easy to access compared with general submarine canyons, it is thought to be one of the best places for studying characteristics of cyclic steps formed by turbidity currents through field observations. In this study, we have analyzed configurations of cyclic steps with the use of data obtained in the field observation of 2011, and compare them with the data from the flume experiments. On the prodelta slope, three major active channels are clearly developed. In addition to the sonar survey, a 600 kHz ADCP was installed in 150m of water just seaward of the termination of the North Channel. In addition, 1200kHz ADCP and 500kHz M3s are suspended from the research vessel in 60 m of water and 300 m distance from the delta edge. We selected images showing large daily differences. The steps move vigorously at the upper 600m parts of the prodelta slope, so that we measured the steps in this area. From the profiles perpendicular to the bedwave crest lines through the center of channels, wavelength and wave height for each step, mean slope were measured on the software for quantitative image analyses manually. Wave steepness for each step was calculated using the wavelength and wave height measured as above. The mean slope ranges from 6.8° ~ 2.7° (more proximal, steeper), mean wavelength and wave heights of steps range from 24.5 to 87.6m

One-dimensional pressure transfer models for acoustic-electric transmission channels

NASA Astrophysics Data System (ADS)

Wilt, K. R.; Lawry, T. J.; Scarton, H. A.; Saulnier, G. J.

2015-09-01

A method for modeling piezoelectric-based ultrasonic acoustic-electric power and data transmission channels is presented. These channels employ piezoelectric disk transducers to convey signals across a series of physical layers using ultrasonic waves. This model decomposes the mechanical pathway of the signal into individual ultrasonic propagation layers which are generally independent of the layer's adjacent domains. Each layer is represented by a two-by-two traveling pressure wave transfer matrix which relates the forward and reverse pressure waves on one side of the layer to the pressure waves on the opposite face, where each face is assumed to be in contact with a domain of arbitrary reference acoustic impedance. A rigorous implementation of ultrasonic beam spreading is introduced and implemented within applicable domains. Compatible pressure-wave models for piezoelectric transducers are given, which relate the electric voltage and current interface of the transducer to the pressure waves on one mechanical interface while also allowing for passive acoustic loading of the secondary mechanical interface. It is also shown that the piezoelectric model's electrical interface is compatible with transmission line parameters (ABCD-parameters), allowing for connection of electronic components and networks. The model is shown to be capable of reproducing the behavior of realistic physical channels.

Physical modeling of vortical cross-step flow in the American paddlefish, Polyodon spathula

PubMed Central

Brooks, Hannah; Haines, Grant E.; Lin, M. Carly

2018-01-01

Vortical cross-step filtration in suspension-feeding fish has been reported recently as a novel mechanism, distinct from other biological and industrial filtration processes. Although crossflow passing over backward-facing steps generates vortices that can suspend, concentrate, and transport particles, the morphological factors affecting this vortical flow have not been identified previously. In our 3D-printed models of the oral cavity for ram suspension-feeding fish, the angle of the backward-facing step with respect to the model’s dorsal midline affected vortex parameters significantly, including rotational, tangential, and axial speed. These vortices were comparable to those quantified downstream of the backward-facing steps that were formed by the branchial arches of preserved American paddlefish in a recirculating flow tank. Our data indicate that vortices in cross-step filtration have the characteristics of forced vortices, as the flow of water inside the oral cavity provides the external torque required to sustain forced vortices. Additionally, we quantified a new variable for ram suspension feeding termed the fluid exit ratio. This is defined as the ratio of the total open pore area for water leaving the oral cavity via spaces between branchial arches that are not blocked by gill rakers, divided by the total area for water entering through the gape during ram suspension feeding. Our experiments demonstrated that the fluid exit ratio in preserved paddlefish was a significant predictor of the flow speeds that were quantified anterior of the rostrum, at the gape, directly dorsal of the first ceratobranchial, and in the forced vortex generated by the first ceratobranchial. Physical modeling of vortical cross-step filtration offers future opportunities to explore the complex interactions between structural features of the oral cavity, vortex parameters, motile particle behavior, and particle morphology that determine the suspension, concentration, and

Molecular basis of activation of the arachidonate-regulated Ca2+ (ARC) channel, a store-independent Orai channel, by plasma membrane STIM1

PubMed Central

Thompson, Jill L; Shuttleworth, Trevor J

2013-01-01

Currently, Orai proteins are known to encode two distinct agonist-activated, highly calcium-selective channels: the store-operated Ca2+ release-activated Ca2+ (CRAC) channels, and the store-independent, arachidonic acid-activated ARC channels. Surprisingly, whilst the trigger for activation of these channels is entirely different, both depend on stromal interacting molecule 1 (STIM1). However, whilst STIM1 in the endoplasmic reticulum membrane is the critical sensor for the depletion of this calcium store that triggers CRAC channel activation, it is the pool of STIM1 constitutively resident in the plasma membrane that is essential for activation of the ARC channels. Here, using a variety of approaches, we show that the key domains within the cytosolic part of STIM1 identified as critical for the activation of CRAC channels are also key for activation of the ARC channels. However, examination of the actual steps involved in such activation reveal marked differences between these two Orai channel types. Specifically, loss of calcium from the EF-hand of STIM1 that forms the key initiation point for activation of the CRAC channels has no effect on ARC channel activity. Secondly, in marked contrast to the dynamic and labile nature of interactions between STIM1 and the CRAC channels, STIM1 in the plasma membrane appears to be constitutively associated with the ARC channels. Finally, specific mutations in STIM1 that induce an extended, constitutively active, conformation for the CRAC channels actually prevent activation of the ARC channels by arachidonic acid. Based on these findings, we propose that the likely role of arachidonic acid lies in inducing the actual gating of the channel. PMID:23690558

Neural synchronization during face-to-face communication.

PubMed

Jiang, Jing; Dai, Bohan; Peng, Danling; Zhu, Chaozhe; Liu, Li; Lu, Chunming

2012-11-07

Although the human brain may have evolutionarily adapted to face-to-face communication, other modes of communication, e.g., telephone and e-mail, increasingly dominate our modern daily life. This study examined the neural difference between face-to-face communication and other types of communication by simultaneously measuring two brains using a hyperscanning approach. The results showed a significant increase in the neural synchronization in the left inferior frontal cortex during a face-to-face dialog between partners but none during a back-to-back dialog, a face-to-face monologue, or a back-to-back monologue. Moreover, the neural synchronization between partners during the face-to-face dialog resulted primarily from the direct interactions between the partners, including multimodal sensory information integration and turn-taking behavior. The communicating behavior during the face-to-face dialog could be predicted accurately based on the neural synchronization level. These results suggest that face-to-face communication, particularly dialog, has special neural features that other types of communication do not have and that the neural synchronization between partners may underlie successful face-to-face communication.

MAGMA: analysis of two-channel microarrays made easy.

PubMed

Rehrauer, Hubert; Zoller, Stefan; Schlapbach, Ralph

2007-07-01

The web application MAGMA provides a simple and intuitive interface to identify differentially expressed genes from two-channel microarray data. While the underlying algorithms are not superior to those of similar web applications, MAGMA is particularly user friendly and can be used without prior training. The user interface guides the novice user through the most typical microarray analysis workflow consisting of data upload, annotation, normalization and statistical analysis. It automatically generates R-scripts that document MAGMA's entire data processing steps, thereby allowing the user to regenerate all results in his local R installation. The implementation of MAGMA follows the model-view-controller design pattern that strictly separates the R-based statistical data processing, the web-representation and the application logic. This modular design makes the application flexible and easily extendible by experts in one of the fields: statistical microarray analysis, web design or software development. State-of-the-art Java Server Faces technology was used to generate the web interface and to perform user input processing. MAGMA's object-oriented modular framework makes it easily extendible and applicable to other fields and demonstrates that modern Java technology is also suitable for rather small and concise academic projects. MAGMA is freely available at www.magma-fgcz.uzh.ch.

The Importance of Splat Events to the Spatiotemporal Structure of Near-Bed Fluid Velocity and Bed Load Motion Over Bed Forms: Laboratory Experiments Downstream of a Backward Facing Step

NASA Astrophysics Data System (ADS)

Leary, K. C. P.; Schmeeckle, M. W.

2017-12-01

Flow separation/reattachment on the lee side of alluvial bed forms is known to produce a complex turbulence field, but the spatiotemporal details of the associated patterns of bed load sediment transported remain largely unknown. Here we report turbulence-resolving, simultaneous measurements of bed load motion and near-bed fluid velocity downstream of a backward facing step in a laboratory flume. Two synchronized high-speed video cameras simultaneously observed bed load motion and the motion of neutrally buoyant particles in a laser light sheet 6 mm above the bed at 250 frames/s downstream of a 3.8 cm backward facing step. Particle Imaging Velocimetry (PIV) and Acoustic Doppler Velocimetry (ADV) were used to characterize fluid turbulent patterns, while manual particle tracking techniques were used to characterize bed load transport. Octant analysis, conducted using ADV data, coupled with Markovian sequence probability analysis highlights differences in the flow near reattachment versus farther downstream. Near reattachment, three distinct flow patterns are apparent. Farther downstream we see the development of a dominant flow sequence. Localized, intermittent, high-magnitude transport events are more apparent near flow reattachment. These events are composed of streamwise and cross-stream fluxes of comparable magnitudes. Transport pattern and fluid velocity data are consistent with the existence of permeable "splat events," wherein a volume of fluid moves toward and impinges on the bed (sweep) causing a radial movement of fluid in all directions around the point of impingement (outward interaction). This is congruent with flow patterns, identified with octant analysis, proximal to flow reattachment.

Solar thermoelectric cooling using closed loop heat exchangers with macro channels

NASA Astrophysics Data System (ADS)

Atta, Raghied M.

2017-07-01

In this paper we describe the design, analysis and experimental study of an advanced coolant air conditioning system which cools or warms airflow using thermoelectric (TE) devices powered by solar cells. Both faces of the TE devices are directly connected to closed-loop highly efficient channels plates with macro scale channels and liquid-to-air heat exchangers. The hot side of the system consists of a pump that moves a coolant through the hot face of the TE modules, a radiator that drives heat away into the air, and a fan that transfer the heat over the radiator by forced convection. The cold side of the system consists also of a pump that moves coolant through the cold face of the TE modules, a radiator that drives cold away into the air, and a fan that blows cold air off the radiator. The system was integrated with solar panels, tested and its thermal performance was assessed. The experimental results verify the possibility of heating or cooling air using TE modules with a relatively high coefficient of performance (COP). The system was able to cool a closed space of 30 m3 by 14 °C below ambient within 90 min. The maximum COP of the whole system was 0.72 when the TE modules were running at 11.2 Å and 12 V. This improvement in the system COP over the air cooled heat sink is due to the improvement of the system heat exchange by means of channels plates.

Purification and Characterization of Two Voltage-Dependent Anion Channel Isoforms from Plant Seeds1

PubMed Central

Abrecht, Helge; Wattiez, Ruddy; Ruysschaert, Jean-Marie; Homblé, Fabrice

2000-01-01

Mitochondria were isolated from imbibed seeds of lentil (Lens culinaris) and Phaseolus vulgaris. We copurified two voltage-dependent anion channel from detergent solubilized mitochondria in a single purification step using hydroxyapatite. The two isoforms from P. vulgaris were separated by chromatofocusing chromatography in 4 m urea without any loss of channel activity. Channel activity of each isoform was characterized upon reconstitution into diphytanoyl phosphatidylcholine planar lipid bilayers. Both isoforms form large conductance channels that are slightly anion selective and display cation selective substates. PMID:11080295

Deliberative Rhetoric as a Step in Organizational Crisis Management: Exxon as a Case Study.

ERIC Educational Resources Information Center

Johnson, Darrin; Sellnow, Timothy

1995-01-01

Explains that when organizations face crises, their rhetorical response often follows two steps: assessment of causes leading to the crisis, and a search for potential solutions and preventive measures for the future. States that epideictic rhetoric designed to sustain or regain the organization's reputation is effective in both steps. Examines…

Adaptive 3D Face Reconstruction from Unconstrained Photo Collections.

PubMed

Roth, Joseph; Tong, Yiying; Liu, Xiaoming

2016-12-07

Given a photo collection of "unconstrained" face images of one individual captured under a variety of unknown pose, expression, and illumination conditions, this paper presents a method for reconstructing a 3D face surface model of the individual along with albedo information. Unlike prior work on face reconstruction that requires large photo collections, we formulate an approach to adapt to photo collections with a high diversity in both the number of images and the image quality. To achieve this, we incorporate prior knowledge about face shape by fitting a 3D morphable model to form a personalized template, following by using a novel photometric stereo formulation to complete the fine details, under a coarse-to-fine scheme. Our scheme incorporates a structural similarity-based local selection step to help identify a common expression for reconstruction while discarding occluded portions of faces. The evaluation of reconstruction performance is through a novel quality measure, in the absence of ground truth 3D scans. Superior large-scale experimental results are reported on synthetic, Internet, and personal photo collections.

Design of a Compact Quad-Channel Diplexer

NASA Astrophysics Data System (ADS)

Xu, Jin

2016-01-01

This paper presents a compact quad-channel diplexer by using two asymmetrical coupling shorted stub loaded stepped-impedance (SSLSIR) dual-band bandpass filters (DB-BPFs) to replace two single-band BPFs in a traditional BPF-based diplexer. Part of its impedance matching circuit is implemented by using a three-element lowpass T-network to acquire the desired phase shift. Detailed design procedures are given to guide the diplexer design. The fabricated quad-channel diplexer occupies a compact circuit area of 0.168λg×0.136λg. High band-to-band isolation and wide stopband performance are achieved. Good agreement is shown between the simulated and measured results.

Numerical characterisation of one-step and three-step solar air heating collectors used for cocoa bean solar drying.

PubMed

Orbegoso, Elder Mendoza; Saavedra, Rafael; Marcelo, Daniel; La Madrid, Raúl

2017-12-01

In the northern coastal and jungle areas of Peru, cocoa beans are dried using artisan methods, such as direct exposure to sunlight. This traditional process is time intensive, leading to a reduction in productivity and, therefore, delays in delivery times. The present study was intended to numerically characterise the thermal behaviour of three configurations of solar air heating collectors in order to determine which demonstrated the best thermal performance under several controlled operating conditions. For this purpose, a computational fluid dynamics model was developed to describe the simultaneous convective and radiative heat transfer phenomena under several operation conditions. The constructed computational fluid dynamics model was firstly validated through comparison with the data measurements of a one-step solar air heating collector. We then simulated two further three-step solar air heating collectors in order to identify which demonstrated the best thermal performance in terms of outlet air temperature and thermal efficiency. The numerical results show that under the same solar irradiation area of exposition and operating conditions, the three-step solar air heating collector with the collector plate mounted between the second and third channels was 67% more thermally efficient compared to the one-step solar air heating collector. This is because the air exposition with the surface of the collector plate for the three-step solar air heating collector former device was twice than the one-step solar air heating collector. Copyright © 2017 Elsevier Ltd. All rights reserved.

Odorant Inhibition of the Olfactory Cyclic Nucleotide-gated Channel with a Native Molecular Assembly

PubMed Central

Chen, Tsung-Yu; Takeuchi, Hiroko; Kurahashi, Takashi

2006-01-01

Human olfaction comprises the opposing actions of excitation and inhibition triggered by odorant molecules. In olfactory receptor neurons, odorant molecules not only trigger a G-protein–coupled signaling cascade but also generate various mechanisms to fine tune the odorant-induced current, including a low-selective odorant inhibition of the olfactory signal. This wide-range olfactory inhibition has been suggested to be at the level of ion channels, but definitive evidence is not available. Here, we report that the cyclic nucleotide-gated (CNG) cation channel, which is a key element that converts odorant stimuli into electrical signals, is inhibited by structurally unrelated odorants, consistent with the expression of wide-range olfactory inhibition. Interestingly, the inhibitory effect was small in the homo-oligomeric CNG channel composed only of the principal channel subunit, CNGA2, but became larger in channels consisting of multiple types of subunits. However, even in the channel containing all native subunits, the potency of the suppression on the cloned CNG channel appeared to be smaller than that previously shown in native olfactory neurons. Nonetheless, our results further showed that odorant suppressions are small in native neurons if the subsequent molecular steps mediated by Ca2+ are removed. Thus, the present work also suggests that CNG channels switch on and off the olfactory signaling pathway, and that the on and off signals may both be amplified by the subsequent olfactory signaling steps. PMID:16940558

Physical Hydraulic Model of Side-Channel Spillway of Lambuk DAM, Bali

NASA Astrophysics Data System (ADS)

Harifa, A. C.; Sholichin, M.; Othman, F. B.

2013-12-01

The spillway is among the most important structures of a dam project. A spillway is designed to prevent overtopping of a dam at a place that is not designed for overtopping. Side-channel spillways are commonly used to release water flow from a reservoir in places where the sides are steep and have a considerable height above the dam. Experimental results were collected with a hydraulic model of the side-channel spillway for releasing the peak overflow of Lambuk Dam. This dam is, located on the Lambuk River, which is a tributary of the Yeh Hoo River ~ 34.6 km north of Denpasar on the island of Bali. The bituminous geomembrane faced dam is 24 m in height, with a 35-m wide spillway. The length of the side channel is 35 m long, with 58 m of transition channel, 67.37 m of chuteway channel and 22.71 m of stilling basin. The capacity of the spillway is 231.91 m3/s and the outlet works capacity is 165.28 m3/s. The reservoir is designed for irrigation and water supply. The purpose of this study was to optimize the designed of the structure and to ensure its safe operation. In hydraulic model may help the decision-makers to visualize the flow field before selecting a ';suitable' design. The hydraulic model study was performed to ensure passage of the maximum discharge at maximum reservoir capacity; to study the spillway approach conditions, water surface profiles, and flow patterns in the chuteway; and to reveal potential demerits of the proposed hydraulic design of various structures and explore solutions. The model was constructed at 1 : 40 scale, Reservoir topography was modeled using concrete, the river bed using sand and some gravel, the river berm using concrete, and the spillway and channel using Plexiglas. Water was measured using Rectangular contracted weir. Design floods (with return period in year) were Q2 = 111.40 m3/s, Q5 = 136.84 m3/s, Q10 = 159.32 m3/s, Q25 = 174.61 m3/s, Q50 = 185.13 m3/s, Q100 = 198.08 m3/s, Q200 = 210.55 m3/s, Q1000 = 231.91 m3/s and the

Perception of 'Back-Channeling' Nonverbal Feedback in Musical Duo Improvisation.

PubMed

Moran, Nikki; Hadley, Lauren V; Bader, Maria; Keller, Peter E

2015-01-01

In witnessing face-to-face conversation, observers perceive authentic communication according to the social contingency of nonverbal feedback cues ('back-channeling') by non-speaking interactors. The current study investigated the generality of this function by focusing on nonverbal communication in musical improvisation. A perceptual experiment was conducted to test whether observers can reliably identify genuine versus fake (mismatched) duos from musicians' nonverbal cues, and how this judgement is affected by observers' musical background and rhythm perception skill. Twenty-four musicians were recruited to perform duo improvisations, which included solo episodes, in two styles: standard jazz (where rhythm is based on a regular pulse) or free improvisation (where rhythm is non-pulsed). The improvisations were recorded using a motion capture system to generate 16 ten-second point-light displays (with audio) of the soloist and the silent non-soloing musician ('back-channeler'). Sixteen further displays were created by splicing soloists with back-channelers from different duos. Participants (N = 60) with various musical backgrounds were asked to rate the point-light displays as either real or fake. Results indicated that participants were sensitive to the real/fake distinction in the free improvisation condition independently of musical experience. Individual differences in rhythm perception skill did not account for performance in the free condition, but were positively correlated with accuracy in the standard jazz condition. These findings suggest that the perception of back-channeling in free improvisation is not dependent on music-specific skills but is a general ability. The findings invite further study of the links between interpersonal dynamics in conversation and musical interaction.

Real time en face Fourier-domain optical coherence tomography with direct hardware frequency demodulation

PubMed Central

Biedermann, Benjamin R.; Wieser, Wolfgang; Eigenwillig, Christoph M.; Palte, Gesa; Adler, Desmond C.; Srinivasan, Vivek J.; Fujimoto, James G.; Huber, Robert

2009-01-01

We demonstrate en face swept source optical coherence tomography (ss-OCT) without requiring a Fourier transformation step. The electronic optical coherence tomography (OCT) interference signal from a k-space linear Fourier domain mode-locked laser is mixed with an adjustable local oscillator, yielding the analytic reflectance signal from one image depth for each frequency sweep of the laser. Furthermore, a method for arbitrarily shaping the spectral intensity profile of the laser is presented, without requiring the step of numerical apodization. In combination, these two techniques enable sampling of the in-phase and quadrature signal with a slow analog-to-digital converter and allow for real-time display of en face projections even for highest axial scan rates. Image data generated with this technique is compared to en face images extracted from a three-dimensional OCT data set. This technique can allow for real-time visualization of arbitrarily oriented en face planes for the purpose of alignment, registration, or operator-guided survey scans while simultaneously maintaining the full capability of high-speed volumetric ss-OCT functionality. PMID:18978919

Numerical simulation of a turbulent flame stabilized behind a rearward-facing step

NASA Technical Reports Server (NTRS)

Hsiao, C. C.; Oppenheim, A. K.; Chorin, A. J.; Ghoniem, A. F.

1985-01-01

Flow of combustible mixtures in a plane channel past a smooth contraction followed by an abrupt expansion, in a typical dump combustor configuration, is modeled by a two-dimensional numerical technique based on the random vortex method. Both the inert and the reacting case are considered. In the latter, the flame is treated as an interface, self-advancing at a prescribed normal burning speed, while the dynamic effects of expansion due to the exothermicity of combustion are expressed by volumetric source lines delineated by its front. Solutions are shown to be in satisfactory agreement with experimental results, especially with respect to global properties such as the average velocity profiles and the reattachment length. The stochastic turbulent velocity components manifest interesting differences, especially near the walls where three-dimensional effects of turbulence are expected to be of importance.

Famous face recognition, face matching, and extraversion.

PubMed

Lander, Karen; Poyarekar, Siddhi

2015-01-01

It has been previously established that extraverts who are skilled at interpersonal interaction perform significantly better than introverts on a face-specific recognition memory task. In our experiment we further investigate the relationship between extraversion and face recognition, focusing on famous face recognition and face matching. Results indicate that more extraverted individuals perform significantly better on an upright famous face recognition task and show significantly larger face inversion effects. However, our results did not find an effect of extraversion on face matching or inverted famous face recognition.

Piston flow in a two-dimensional channel

NASA Astrophysics Data System (ADS)

Katopodes, Fotini V.; Davis, A. M. J.; Stone, H. A.

2000-05-01

A solution using biorthogonal eigenfunctions is presented for viscous flow caused by a piston in a two-dimensional channel. The resulting infinite set of linear equations is solved using Spence's optimal weighting function method [IMA J. Appl. Math. 30, 107 (1983)]. The solution is compared to that with a shear-free piston surface; in the latter configuration the fluid more rapidly approaches the Poiseuille flow profile established away from the face of the piston.

Face biometrics with renewable templates

NASA Astrophysics Data System (ADS)

van der Veen, Michiel; Kevenaar, Tom; Schrijen, Geert-Jan; Akkermans, Ton H.; Zuo, Fei

2006-02-01

In recent literature, privacy protection technologies for biometric templates were proposed. Among these is the so-called helper-data system (HDS) based on reliable component selection. In this paper we integrate this approach with face biometrics such that we achieve a system in which the templates are privacy protected, and multiple templates can be derived from the same facial image for the purpose of template renewability. Extracting binary feature vectors forms an essential step in this process. Using the FERET and Caltech databases, we show that this quantization step does not significantly degrade the classification performance compared to, for example, traditional correlation-based classifiers. The binary feature vectors are integrated in the HDS leading to a privacy protected facial recognition algorithm with acceptable FAR and FRR, provided that the intra-class variation is sufficiently small. This suggests that a controlled enrollment procedure with a sufficient number of enrollment measurements is required.

Imaging the eye fundus with real-time en-face spectral domain optical coherence tomography

PubMed Central

Bradu, Adrian; Podoleanu, Adrian Gh.

2014-01-01

Real-time display of processed en-face spectral domain optical coherence tomography (SD-OCT) images is important for diagnosis. However, due to many steps of data processing requirements, such as Fast Fourier transformation (FFT), data re-sampling, spectral shaping, apodization, zero padding, followed by software cut of the 3D volume acquired to produce an en-face slice, conventional high-speed SD-OCT cannot render an en-face OCT image in real time. Recently we demonstrated a Master/Slave (MS)-OCT method that is highly parallelizable, as it provides reflectivity values of points at depth within an A-scan in parallel. This allows direct production of en-face images. In addition, the MS-OCT method does not require data linearization, which further simplifies the processing. The computation in our previous paper was however time consuming. In this paper we present an optimized algorithm that can be used to provide en-face MS-OCT images much quicker. Using such an algorithm we demonstrate around 10 times faster production of sets of en-face OCT images than previously obtained as well as simultaneous real-time display of up to 4 en-face OCT images of 200 × 200 pixels2 from the fovea and the optic nerve of a volunteer. We also demonstrate 3D and B-scan OCT images obtained from sets of MS-OCT C-scans, i.e. with no FFT and no intermediate step of generation of A-scans. PMID:24761303

Modeling bed load transport and step-pool morphology with a reduced-complexity approach

NASA Astrophysics Data System (ADS)

Saletti, Matteo; Molnar, Peter; Hassan, Marwan A.; Burlando, Paolo

2016-04-01

Steep mountain channels are complex fluvial systems, where classical methods developed for lowland streams fail to capture the dynamics of sediment transport and bed morphology. Estimations of sediment transport based on average conditions have more than one order of magnitude of uncertainty because of the wide grain-size distribution of the bed material, the small relative submergence of coarse grains, the episodic character of sediment supply, and the complex boundary conditions. Most notably, bed load transport is modulated by the structure of the bed, where grains are imbricated in steps and similar bedforms and, therefore, they are much more stable then predicted. In this work we propose a new model based on a reduced-complexity (RC) approach focused on the reproduction of the step-pool morphology. In our 2-D cellular-automaton model entrainment, transport and deposition of particles are considered via intuitive rules based on physical principles. A parsimonious set of parameters allows the control of the behavior of the system, and the basic processes can be considered in a deterministic or stochastic way. The probability of entrainment of grains (and, as a consequence, particle travel distances and resting times) is a function of flow conditions and bed topography. Sediment input is fed at the upper boundary of the channel at a constant or variable rate. Our model yields realistic results in terms of longitudinal bed profiles and sediment transport trends. Phases of aggradation and degradation can be observed in the channel even under a constant input and the memory of the morphology can be quantified with long-range persistence indicators. Sediment yield at the channel outlet shows intermittency as observed in natural streams. Steps are self-formed in the channel and their stability is tested against the model parameters. Our results show the potential of RC models as complementary tools to more sophisticated models. They provide a realistic description of

Perception of Sexual Orientation from Facial Structure: A Study with Artificial Face Models.

PubMed

González-Álvarez, Julio

2017-07-01

Research has shown that lay people can perceive sexual orientation better than chance from face stimuli. However, the relation between facial structure and sexual orientation has been scarcely examined. Recently, an extensive morphometric study on a large sample of Canadian people (Skorska, Geniole, Vrysen, McCormick, & Bogaert, 2015) identified three (in men) and four (in women) facial features as unique multivariate predictors of sexual orientation in each sex group. The present study tested the perceptual validity of these facial traits with two experiments based on realistic artificial 3D face models created by manipulating the key parameters and presented to Spanish participants. Experiment 1 included 200 White and Black face models of both sexes. The results showed an overall accuracy (0.74) clearly above chance in a binary hetero/homosexual judgment task and significant differences depending on the race and sex of the face models. Experiment 2 produced five versions of 24 artificial faces of both sexes varying the key parameters in equal steps, and participants had to rate on a 1-7 scale how likely they thought that the depicted person had a homosexual sexual orientation. Rating scores displayed an almost perfect linear regression as a function of the parameter steps. In summary, both experiments demonstrated the perceptual validity of the seven multivariate predictors identified by Skorska et al. and open up new avenues for further research on this issue with artificial face models.

Determining geometric error model parameters of a terrestrial laser scanner through Two-face, Length-consistency, and Network methods

PubMed Central

Wang, Ling; Muralikrishnan, Bala; Rachakonda, Prem; Sawyer, Daniel

2017-01-01

Terrestrial laser scanners (TLS) are increasingly used in large-scale manufacturing and assembly where required measurement uncertainties are on the order of few tenths of a millimeter or smaller. In order to meet these stringent requirements, systematic errors within a TLS are compensated in-situ through self-calibration. In the Network method of self-calibration, numerous targets distributed in the work-volume are measured from multiple locations with the TLS to determine parameters of the TLS error model. In this paper, we propose two new self-calibration methods, the Two-face method and the Length-consistency method. The Length-consistency method is proposed as a more efficient way of realizing the Network method where the length between any pair of targets from multiple TLS positions are compared to determine TLS model parameters. The Two-face method is a two-step process. In the first step, many model parameters are determined directly from the difference between front-face and back-face measurements of targets distributed in the work volume. In the second step, all remaining model parameters are determined through the Length-consistency method. We compare the Two-face method, the Length-consistency method, and the Network method in terms of the uncertainties in the model parameters, and demonstrate the validity of our techniques using a calibrated scale bar and front-face back-face target measurements. The clear advantage of these self-calibration methods is that a reference instrument or calibrated artifacts are not required, thus significantly lowering the cost involved in the calibration process. PMID:28890607

Face recognition system and method using face pattern words and face pattern bytes

DOEpatents

Zheng, Yufeng

2014-12-23

The present invention provides a novel system and method for identifying individuals and for face recognition utilizing facial features for face identification. The system and method of the invention comprise creating facial features or face patterns called face pattern words and face pattern bytes for face identification. The invention also provides for pattern recognitions for identification other than face recognition. The invention further provides a means for identifying individuals based on visible and/or thermal images of those individuals by utilizing computer software implemented by instructions on a computer or computer system and a computer readable medium containing instructions on a computer system for face recognition and identification.

NIFLUMIC ACID BLOCKS NATIVE AND RECOMBINANT T-TYPE CHANNELS

PubMed Central

Balderas, E; Arteaga-Tlecuitl, R; Rivera, M; Gomora, JC; Darszon, A

2012-01-01

Voltage-dependent calcium channels are widely distributed in animal cells, including spermatozoa. Calcium is fundamental in many sperm functions such as: motility, capacitation and the acrosome reaction, all essential for fertilization. Pharmacological evidence has suggested T-type calcium channels participate in the acrosome reaction. Niflumic acid (NA), a non-steroidal anti-inflammatory drug commonly used as chloride channel blocker, blocks T-currents in mouse spermatogenic cells and Cl− channels in testicular sperm. Here we examine the mechanism of NA blockade and explore if it can be used to separate the contribution of different CaV3 members previously detected in these cells. Electrophysiological patch-clamp recordings were performed in isolated mouse spermatogenic cells and in HEK cells heterologously expressing CaV3 channels. NA blocks mouse spermatogenic cell T-type currents with an IC50 of 73.5 µM, without major voltage-dependent effects. The NA blockade is more potent in the open and in the inactivated state than in the closed state of the T-type channels. Interestingly, we found that heterologously expressed CaV3.1 and CaV3.3 channels were more sensitive to NA than CaV3.2 channels, and this drug substantially slowed the recovery from inactivation of the three isoforms. Molecular docking modeling of drug-channel binding predicts that NA binds preferentially to the extracellular face of CaV3.1 channels. The biophysical characteristics of mouse spermatogenic cell T-type currents more closely resemble those from heterologously expressed CaV3.1 channels, including their sensitivity to NA. As CaV3.1 null mice maintain their spermatogenic cell T-currents, it is likely that a novel CaV3.2 isoform is responsible for them. PMID:21898399

Hyperspectral face recognition using improved inter-channel alignment based on qualitative prediction models.

PubMed

Cho, Woon; Jang, Jinbeum; Koschan, Andreas; Abidi, Mongi A; Paik, Joonki

2016-11-28

A fundamental limitation of hyperspectral imaging is the inter-band misalignment correlated with subject motion during data acquisition. One way of resolving this problem is to assess the alignment quality of hyperspectral image cubes derived from the state-of-the-art alignment methods. In this paper, we present an automatic selection framework for the optimal alignment method to improve the performance of face recognition. Specifically, we develop two qualitative prediction models based on: 1) a principal curvature map for evaluating the similarity index between sequential target bands and a reference band in the hyperspectral image cube as a full-reference metric; and 2) the cumulative probability of target colors in the HSV color space for evaluating the alignment index of a single sRGB image rendered using all of the bands of the hyperspectral image cube as a no-reference metric. We verify the efficacy of the proposed metrics on a new large-scale database, demonstrating a higher prediction accuracy in determining improved alignment compared to two full-reference and five no-reference image quality metrics. We also validate the ability of the proposed framework to improve hyperspectral face recognition.

The electrical response of turtle cones to flashes and steps of light.

PubMed

Baylor, D A; Hodgkin, A L; Lamb, T D

1974-11-01

1. The linear response of turtle cones to weak flashes or steps of light was usually well fitted by equations based on a chain of six or seven reactions with time constants varying over about a 6-fold range.2. The temperature coefficient (Q(10)) of the reciprocal of the time to peak of the response to a flash was 1.8 (15-25 degrees C), corresponding to an activation energy of 10 kcal/mole.3. Electrical measurements with one internal electrode and a balancing circuit gave the following results on red-sensitive cones of high resistance: resistance across cell surface in dark 50-170 MOmega; time constant in dark 4-6.5 msec. The effect of a bright light was to increase the resistance and time constant by 10-30%.4. If the cell time constant, resting potential and maximum hyperpolarization are known, the fraction of ionic channels blocked by light at any instant can be calculated from the hyperpolarization and its rate of change. At times less than 50 msec the shape of this relation is consistent with the idea that the concentration of a blocking molecule which varies linearly with light intensity is in equilibrium with the fraction of ionic channels blocked.5. The rising phase of the response to flashes and steps of light covering a 10(5)-fold range of intensities is well fitted by a theory in which the essential assumptions are that (i) light starts a linear chain of reactions leading to the production of a substance which blocks ionic channels in the outer segment, (ii) an equilibrium between the blocking molecules and unblocked channels is established rapidly, and (iii) the electrical properties of the cell can be represented by a simple circuit with a time constant in the dark of about 6 msec.6. Deviations from the simple theory which occur after 50 msec are attributed partly to a time-dependent desensitization mechanism and partly to a change in saturation potential resulting from a voltage-dependent change in conductance.7. The existence of several components in

Crystal faces of anhydrite (CaSO 4) and their preferential dissolution in aqueous solutions studied with AFM

NASA Astrophysics Data System (ADS)

Shindo, H.; Kaise, M.; Kondoh, H.; Nishihara, C.; Nozoye, H.

Structures of cleaved surfaces of anhydrite were studied with atomic force microscopy (AFM) before and after partial dissolution in aqueous solutions of NH 4Cl and NaHSO 4. Two crystal faces showed atom-resolved images just after cleavage, (100) and (010), of which the former was roughened by the dissolution, while step structures were developed on the latter. After dissolution, steplines ran along the a- and c-axes on the (010) face, while they ran in directions inclined to these axes before. It was revealed that the arrangement of dipoles is a key factor in determining stabilities of step structures on crystal faces. On the terraces, the arrangement of oxygen atoms of the sulfate groups and calcium ions were clearly observed.

Mechanosensitive channels: feeling tension in a world under pressure.

PubMed

Peyronnet, Rémi; Tran, Daniel; Girault, Tiffanie; Frachisse, Jean-Marie

2014-01-01

Plants, like other organisms, are facing multiple mechanical constraints generated both in their tissues and by the surrounding environments. They need to sense and adapt to these forces throughout their lifetimes. To do so, different mechanisms devoted to force transduction have emerged. Here we focus on fascinating proteins: the mechanosensitive (MS) channels. Mechanosensing in plants has been described for centuries but the molecular identification of MS channels occurred only recently. This review is aimed at plant biologists and plant biomechanists who want to be introduced to MS channel identity, how they work and what they might do in planta? In this review, electrophysiological properties, regulations, and functions of well-characterized MS channels belonging to bacteria and animals are compared with those of plants. Common and specific properties are discussed. We deduce which tools and concepts from animal and bacterial fields could be helpful for improving our understanding of plant mechanotransduction. MS channels embedded in their plasma membrane are sandwiched between the cell wall and the cytoskeleton. The consequences of this peculiar situation are analyzed and discussed. We also stress how important it is to probe mechanical forces at cellular and subcellular levels in planta in order to reveal the intimate relationship linking the membrane with MS channel activity. Finally we will propose new tracks to help to reveal their physiological functions at tissue and plant levels.

Automatic design of conformal cooling channels in injection molding tooling

NASA Astrophysics Data System (ADS)

Zhang, Yingming; Hou, Binkui; Wang, Qian; Li, Yang; Huang, Zhigao

2018-02-01

The generation of cooling system plays an important role in injection molding design. A conformal cooling system can effectively improve molding efficiency and product quality. This paper provides a generic approach for building conformal cooling channels. The centrelines of these channels are generated in two steps. First, we extract conformal loops based on geometric information of product. Second, centrelines in spiral shape are built by blending these loops. We devise algorithms to implement the entire design process. A case study verifies the feasibility of this approach.

Starting a new residency program: a step-by-step guide for institutions, hospitals, and program directors

PubMed Central

Barajaz, Michelle; Turner, Teri

2016-01-01

Although our country faces a looming shortage of doctors, constraints of space, funding, and patient volume in many existing residency programs limit training opportunities for medical graduates. New residency programs need to be created for the expansion of graduate medical education training positions. Partnerships between existing academic institutions and community hospitals with a need for physicians can be a very successful means toward this end. Baylor College of Medicine and The Children's Hospital of San Antonio were affiliated in 2012, and subsequently, we developed and received accreditation for a new categorical pediatric residency program at that site in 2014. We share below a step-by-step guide through the process that includes building of the infrastructure, educational development, accreditation, marketing, and recruitment. It is our hope that the description of this process will help others to spur growth in graduate medical training positions. PMID:27507541

Variable is better than invariable: sparse VSS-NLMS algorithms with application to adaptive MIMO channel estimation.

PubMed

Gui, Guan; Chen, Zhang-xin; Xu, Li; Wan, Qun; Huang, Jiyan; Adachi, Fumiyuki

2014-01-01

Channel estimation problem is one of the key technical issues in sparse frequency-selective fading multiple-input multiple-output (MIMO) communication systems using orthogonal frequency division multiplexing (OFDM) scheme. To estimate sparse MIMO channels, sparse invariable step-size normalized least mean square (ISS-NLMS) algorithms were applied to adaptive sparse channel estimation (ACSE). It is well known that step-size is a critical parameter which controls three aspects: algorithm stability, estimation performance, and computational cost. However, traditional methods are vulnerable to cause estimation performance loss because ISS cannot balance the three aspects simultaneously. In this paper, we propose two stable sparse variable step-size NLMS (VSS-NLMS) algorithms to improve the accuracy of MIMO channel estimators. First, ASCE is formulated in MIMO-OFDM systems. Second, different sparse penalties are introduced to VSS-NLMS algorithm for ASCE. In addition, difference between sparse ISS-NLMS algorithms and sparse VSS-NLMS ones is explained and their lower bounds are also derived. At last, to verify the effectiveness of the proposed algorithms for ASCE, several selected simulation results are shown to prove that the proposed sparse VSS-NLMS algorithms can achieve better estimation performance than the conventional methods via mean square error (MSE) and bit error rate (BER) metrics.

Variable Is Better Than Invariable: Sparse VSS-NLMS Algorithms with Application to Adaptive MIMO Channel Estimation

PubMed Central

Gui, Guan; Chen, Zhang-xin; Xu, Li; Wan, Qun; Huang, Jiyan; Adachi, Fumiyuki

2014-01-01

Channel estimation problem is one of the key technical issues in sparse frequency-selective fading multiple-input multiple-output (MIMO) communication systems using orthogonal frequency division multiplexing (OFDM) scheme. To estimate sparse MIMO channels, sparse invariable step-size normalized least mean square (ISS-NLMS) algorithms were applied to adaptive sparse channel estimation (ACSE). It is well known that step-size is a critical parameter which controls three aspects: algorithm stability, estimation performance, and computational cost. However, traditional methods are vulnerable to cause estimation performance loss because ISS cannot balance the three aspects simultaneously. In this paper, we propose two stable sparse variable step-size NLMS (VSS-NLMS) algorithms to improve the accuracy of MIMO channel estimators. First, ASCE is formulated in MIMO-OFDM systems. Second, different sparse penalties are introduced to VSS-NLMS algorithm for ASCE. In addition, difference between sparse ISS-NLMS algorithms and sparse VSS-NLMS ones is explained and their lower bounds are also derived. At last, to verify the effectiveness of the proposed algorithms for ASCE, several selected simulation results are shown to prove that the proposed sparse VSS-NLMS algorithms can achieve better estimation performance than the conventional methods via mean square error (MSE) and bit error rate (BER) metrics. PMID:25089286

Multi-channel time-reversal receivers for multi and 1-bit implementations

DOEpatents

Candy, James V.; Chambers, David H.; Guidry, Brian L.; Poggio, Andrew J.; Robbins, Christopher L.

2008-12-09

A communication system for transmitting a signal through a channel medium comprising digitizing the signal, time-reversing the digitized signal, and transmitting the signal through the channel medium. In one embodiment a transmitter is adapted to transmit the signal, a multiplicity of receivers are adapted to receive the signal, a digitizer digitizes the signal, and a time-reversal signal processor is adapted to time-reverse the digitized signal. An embodiment of the present invention includes multi bit implementations. Another embodiment of the present invention includes 1-bit implementations. Another embodiment of the present invention includes a multiplicity of receivers used in the step of transmitting the signal through the channel medium.

Virtual & Real Face to Face Teaching

ERIC Educational Resources Information Center

Teneqexhi, Romeo; Kuneshka, Loreta

2016-01-01

In traditional "face to face" lessons, during the time the teacher writes on a black or white board, the students are always behind the teacher. Sometimes, this happens even in the recorded lesson in videos. Most of the time during the lesson, the teacher shows to the students his back not his face. We do not think the term "face to…

Long-Range Reduced Predictive Information Transfers of Autistic Youths in EEG Sensor-Space During Face Processing.

PubMed

Khadem, Ali; Hossein-Zadeh, Gholam-Ali; Khorrami, Anahita

2016-03-01

The majority of previous functional/effective connectivity studies conducted on the autistic patients converged to the underconnectivity theory of ASD: "long-range underconnectivity and sometimes short-rang overconnectivity". However, to the best of our knowledge the total (linear and nonlinear) predictive information transfers (PITs) of autistic patients have not been investigated yet. Also, EEG data have rarely been used for exploring the information processing deficits in autistic subjects. This study is aimed at comparing the total (linear and nonlinear) PITs of autistic and typically developing healthy youths during human face processing by using EEG data. The ERPs of 12 autistic youths and 19 age-matched healthy control (HC) subjects were recorded while they were watching upright and inverted human face images. The PITs among EEG channels were quantified using two measures separately: transfer entropy with self-prediction optimality (TESPO), and modified transfer entropy with self-prediction optimality (MTESPO). Afterwards, the directed differential connectivity graphs (dDCGs) were constructed to characterize the significant changes in the estimated PITs of autistic subjects compared with HC ones. By using both TESPO and MTESPO, long-range reduction of PITs of ASD group during face processing was revealed (particularly from frontal channels to right temporal channels). Also, it seemed the orientation of face images (upright or upside down) did not modulate the binary pattern of PIT-based dDCGs, significantly. Moreover, compared with TESPO, the results of MTESPO were more compatible with the underconnectivity theory of ASD in the sense that MTESPO showed no long-range increase in PIT. It is also noteworthy that to the best of our knowledge it is the first time that a version of MTE is applied for patients (here ASD) and it is also its first use for EEG data analysis.

Evolution of Channels Draining Mount St. Helens: Linking Non-Linear and Rapid, Threshold Responses

NASA Astrophysics Data System (ADS)

Simon, A.

2010-12-01

The catastrophic eruption of Mount St. Helens buried the valley of the North Fork Toutle River (NFT) to a depth of up to 140 m. Initial integration of a new drainage network took place episodically by the “filling and spilling” (from precipitation and seepage) of depressions formed during emplacement of the debris avalanche deposit. Channel incision to depths of 20-30 m occurred in the debris avalanche and extensive pyroclastic flow deposits, and headward migration of the channel network followed, with complete integration taking place within 2.5 years. Downstream reaches were converted from gravel-cobble streams with step-pool sequences to smoothed, infilled channels dominated by sand-sized materials. Subsequent channel evolution was dominated by channel widening with the ratio of changes in channel width to changes in channel depth ranging from about 60 to 100. Widening resulted in significant adjustment of hydraulic variables that control sediment-transport rates. For a given discharge over time, flow depths were reduced, relative roughness increased and flow velocity and boundary shear stress decreased non-linearly. These changes, in combination with coarsening of the channel bed with time resulted in systematically reduced rates of degradation (in upstream reaches), aggradation (in downstream reaches) and sediment-transport rates through much of the 1990s. Vertical adjustments were, therefore, easy to characterize with non-linear decay functions with bed-elevation attenuating with time. An empirical model of bed-level response was then created by plotting the total dimensionless change in elevation against river kilometer for both initial and secondary vertical adjustments. High magnitude events generated from the generated from upper part of the mountain, however, can cause rapid (threshold) morphologic changes. For example, a rain-on-snow event in November 2006 caused up to 9 m of incision along a 6.5 km reach of Loowit Creek and the upper NFT. The event

Properties of Single K+ and Cl− Channels in Asclepias tuberosa Protoplasts 1

PubMed Central

Schauf, Charles L.; Wilson, Kathryn J.

1987-01-01

Potassium and chloride channels were characterized in Asclepias tuberosa suspension cell derived protoplasts by patch voltage-clamp. Whole-cell currents and single channels in excised patches had linear instantaneous current-voltage relations, reversing at the Nernst potentials for K+ and Cl−, respectively. Whole cell K+ currents activated exponentially during step depolarizations, while voltage-dependent Cl− channels were activated by hyperpolarizations. Single K+ channel conductance was 40 ± 5 pS with a mean open time of 4.5 milliseconds at 100 millivolts. Potassium channels were blocked by Cs+ and tetraethylammonium, but were insensitive to 4-aminopyridine. Chloride channels had a single-channel conductance of 100 ± 17 picosiemens, mean open time of 8.8 milliseconds, and were blocked by Zn2+ and ethacrynic acid. Whole-cell Cl− currents were inhibited by abscisic acid, and were unaffected by indole-3-acetic acid and 2,4-dichlorophenoxyacetic acid. Since internal and external composition can be controlled, patch-clamped protoplasts are ideal systems for studying the role of ion channels in plant physiology and development. Images Fig. 5 PMID:16665712

Framing faces: Frame alignment impacts holistic face perception.

PubMed

Curby, Kim M; Entenman, Robert

2016-11-01

Traditional accounts of face perception emphasise the importance of the prototypical configuration of features within faces. However, here we probe influences of more general perceptual grouping mechanisms on holistic face perception. Participants made part-matching judgments about composite faces presented in intact external oval frames or frames made from misaligned oval parts. This manipulation served to disrupt basic perceptual grouping cues that facilitate the grouping of the two face halves together. This manipulation also produced an external face contour like that in the standard misaligned condition used within the classic composite face task. Notably, by introducing a discontinuity in the external contour, grouping of the face halves into a cohesive unit was discouraged, but face configuration was preserved. Conditions where both the face parts and the frames were misaligned together, as in the typical composite task paradigm, or where just the internal face parts where misaligned, were also included. Disrupting only the face frame similarly disrupted holistic face perception as disrupting both the frame and face configuration. However, misaligned face parts presented in aligned frames also incurred a cost to holistic perception. These findings provide support for the contribution of general-purpose perceptual grouping mechanisms to holistic face perception and are presented and discussed in the context of an enhanced object-based selection account of holistic perception.

Voltage-Dependent Gating: Novel Insights from KCNQ1 Channels

PubMed Central

Cui, Jianmin

2016-01-01

Gating of voltage-dependent cation channels involves three general molecular processes: voltage sensor activation, sensor-pore coupling, and pore opening. KCNQ1 is a voltage-gated potassium (Kv) channel whose distinctive properties have provided novel insights on fundamental principles of voltage-dependent gating. 1) Similar to other Kv channels, KCNQ1 voltage sensor activation undergoes two resolvable steps; but, unique to KCNQ1, the pore opens at both the intermediate and activated state of voltage sensor activation. The voltage sensor-pore coupling differs in the intermediate-open and the activated-open states, resulting in changes of open pore properties during voltage sensor activation. 2) The voltage sensor-pore coupling and pore opening require the membrane lipid PIP2 and intracellular ATP, respectively, as cofactors, thus voltage-dependent gating is dependent on multiple stimuli, including the binding of intracellular signaling molecules. These mechanisms underlie the extraordinary KCNE1 subunit modification of the KCNQ1 channel and have significant physiological implications. PMID:26745405

On the number of channels needed to classify vowels: Implications for cochlear implants

NASA Astrophysics Data System (ADS)

Fourakis, Marios; Hawks, John W.; Davis, Erin

2005-09-01

In cochlear implants the incoming signal is analyzed by a bank of filters. Each filter is associated with an electrode to constitute a channel. The present research seeks to determine the number of channels needed for optimal vowel classification. Formant measurements of vowels produced by men and women [Hillenbrand et al., J. Acoust. Soc. Am. 97, 3099-3111 (1995)] were converted to channel assignments. The number of channels varied from 4 to 20 over two frequency ranges (180-4000 and 180-6000 Hz) in equal bark steps. Channel assignments were submitted to linear discriminant analysis (LDA). Classification accuracy increased with the number of channels, ranging from 30% with 4 channels to 98% with 20 channels, both for the female voice. To determine asymptotic performance, LDA classification scores were plotted against the number of channels and fitted with quadratic equations. The number of channels at which no further improvement occurred was determined, averaging 19 across all conditions with little variation. This number of channels seems to resolve the frequency range spanned by the first three formants finely enough to maximize vowel classification. This resolution may not be achieved using six or eight channels as previously proposed. [Work supported by NIH.

MscS-Like Mechanosensitive Channels in Plants and Microbes

PubMed Central

Wilson, Margaret E.; Maksaev, Grigory; Haswell, Elizabeth S.

2013-01-01

The challenge of osmotic stress is something all living organisms must face as a result of environmental dynamics. Over the past three decades, innovative research and cooperation across disciplines has irrefutably established that cells utilize mechanically gated ion channels to release osmolytes and prevent cell lysis during hypoosmotic stress. Early electrophysiological analysis of the inner membrane of Escherichia coli identified the presence of three distinct mechanosensitive activities. The subsequent discoveries of the genes responsible for two of these activities, the mechanosensitive channels of large (MscL) and small (MscS) conductance, led to the identification of two diverse families of mechanosensitive channels. The latter of these two families, the MscS family, is made up of members from bacteria, archaea, fungi, and plants. Genetic and electrophysiological analysis of these family members has provided insight into how organisms use mechanosensitive channels for osmotic regulation in response to changing environmental and developmental circumstances. Furthermore, solving the crystal structure of E. coli MscS and several homologs in several conformational states has contributed to the understanding of the gating mechanisms of these channels. Here we summarize our current knowledge of MscS homologs from all three domains of life, and address their structure, proposed physiological functions, electrophysiological behaviors, and topological diversity. PMID:23947546

Direct etch method for microfludic channel and nanoheight post-fabrication by picoliter droplets

NASA Astrophysics Data System (ADS)

Demirci, Utkan; Toner, Mehmet

2006-01-01

Photolithography is an expensive and significant step in microfabrication. Approaches that could change lithography would create an impact on semiconductor industry and microelectromechanical systems technologies. We demonstrate a direct etching method by ejecting etchant droplets at desired locations by using microdroplet ejector arrays. This method could be used for easy fabrication of poly(dimethylsiloxane) microfluidic channels and nanometer height postlike structures in microfluidic channels.

Wildlife use of back channels associated with islands on the Ohio River

USGS Publications Warehouse

Zadnik, A.K.; Anderson, James T.; Wood, P.B.; Bledsoe, K.

2009-01-01

The back channels of islands on the Ohio River are assumed to provide habitat critical for several wildlife species. However, quantitative information on the wildlife value of back channels is needed by natural resource managers for the conservation of these forested islands and embayments in the face of increasing shoreline development and recreational boating. We compared the relative abundance of waterbirds, turtles, anurans, and riparian furbearing mammals during 2001 and 2002 in back and main channels of the Ohio River in West Virginia. Wood ducks (Aix sponsa), snapping turtles (Chelydra serpentina), beavers (Castor canadensis), and muskrats (Ondatra zibethicus) were more abundant in back than main channels. Spring peepers (Pseudacris crucifer) and American toads (Bufo americanus) occurred more frequently on back than main channels. These results provide quantitative evidence that back channels are important for several wildlife species. The narrowness of the back channels, the protection they provide from the main current of the river, and their ability to support vegetated shorelines and woody debris, are characteristics that appear to benefit these species. As a conservation measure for important riparian wildlife habitat, we suggest limiting building of piers and development of the shoreline in back channel areas. ?? 2009, The Society of Wetland Scientists.

How Well Do Computer-Generated Faces Tap Face Expertise?

PubMed

Crookes, Kate; Ewing, Louise; Gildenhuys, Ju-Dith; Kloth, Nadine; Hayward, William G; Oxner, Matt; Pond, Stephen; Rhodes, Gillian

2015-01-01

The use of computer-generated (CG) stimuli in face processing research is proliferating due to the ease with which faces can be generated, standardised and manipulated. However there has been surprisingly little research into whether CG faces are processed in the same way as photographs of real faces. The present study assessed how well CG faces tap face identity expertise by investigating whether two indicators of face expertise are reduced for CG faces when compared to face photographs. These indicators were accuracy for identification of own-race faces and the other-race effect (ORE)-the well-established finding that own-race faces are recognised more accurately than other-race faces. In Experiment 1 Caucasian and Asian participants completed a recognition memory task for own- and other-race real and CG faces. Overall accuracy for own-race faces was dramatically reduced for CG compared to real faces and the ORE was significantly and substantially attenuated for CG faces. Experiment 2 investigated perceptual discrimination for own- and other-race real and CG faces with Caucasian and Asian participants. Here again, accuracy for own-race faces was significantly reduced for CG compared to real faces. However the ORE was not affected by format. Together these results signal that CG faces of the type tested here do not fully tap face expertise. Technological advancement may, in the future, produce CG faces that are equivalent to real photographs. Until then caution is advised when interpreting results obtained using CG faces.

Packaging system with cleaning channel and method of making the same

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fang, Lu

A packaging structure and method for surface mount integrated circuits reduces electrochemical migration (ECM) problems by including one or more cleaning channels to effectively and efficiently remove flux residue that may otherwise remain lodged in gaps between the surface mount package and the printed circuit board. A cleaning channel may be formed along a bottom surface of the surface mount package (i.e., the surface facing the printed circuit board), or along a portion of a top surface of the printed circuit board. In either case, the inclusion of a cleaning channel enlarges the gap between the bottom surface of themore » surface mount package and the printed circuit board and creates a path for contaminants to be flushed out during a cleaning process.« less

Functional selectivity for face processing in the temporal voice area of early deaf individuals

PubMed Central

van Ackeren, Markus J.; Rabini, Giuseppe; Zonca, Joshua; Foa, Valentina; Baruffaldi, Francesca; Rezk, Mohamed; Pavani, Francesco; Rossion, Bruno; Collignon, Olivier

2017-01-01

Brain systems supporting face and voice processing both contribute to the extraction of important information for social interaction (e.g., person identity). How does the brain reorganize when one of these channels is absent? Here, we explore this question by combining behavioral and multimodal neuroimaging measures (magneto-encephalography and functional imaging) in a group of early deaf humans. We show enhanced selective neural response for faces and for individual face coding in a specific region of the auditory cortex that is typically specialized for voice perception in hearing individuals. In this region, selectivity to face signals emerges early in the visual processing hierarchy, shortly after typical face-selective responses in the ventral visual pathway. Functional and effective connectivity analyses suggest reorganization in long-range connections from early visual areas to the face-selective temporal area in individuals with early and profound deafness. Altogether, these observations demonstrate that regions that typically specialize for voice processing in the hearing brain preferentially reorganize for face processing in born-deaf people. Our results support the idea that cross-modal plasticity in the case of early sensory deprivation relates to the original functional specialization of the reorganized brain regions. PMID:28652333

Linking recent observations of cyclic steps from fjords to outcropping stratigraphic products, British Columbia, Canada

NASA Astrophysics Data System (ADS)

Hubbard, S. M.; Coutts, D. S.; Covault, J. A.

2016-12-01

Repeated bathymetric surveys of fjord prodeltas in Western Canada track channel erosion and deposition, which is interpreted to result from upstream migrating cyclic steps. Cyclic steps are long-wave (the ratio of wavelength to height is >>1), upstream-migrating bedforms that develop as a result of repeated internal hydraulic jumps in an overriding turbidity current at lee-to-stoss slope breaks. An internal hydraulic jump is the result of a transition from subaqueous densimetric Froude supercritical to subcritical flow. As the supercritical bedforms migrate greater than 90% of the deposits are reworked, making morphology- and facies- based recognition challenging in the depositional record. The objectives of this work are to use predictions of remnant bedform geometry from repeat bathymetric surveys to recognize cyclic step deposits in the stratigraphic record. We compare fjord deposits to Late Cretaceous submarine channel strata of the Nanaimo Group at Gabriola Island, British Columbia. In the Squamish prodelta, sediment accumulation on the stoss side of cyclic steps and erosion on the lee side promotes their up-slope migration. Deposits are modified by overriding turbidity currents, resulting in sedimentary bodies 5-30 m long, 0.5-2 m thick and < 30 m wide. The Nanaimo Group comprises scour fills of similar scale composed of stratified sandstone, with laminated siltstone locally overlying basal erosion surfaces. Up-slope dipping backset stratification is widely observed; packages of 2-4 backset beds, each of which are up to 60 cm thick and up to 15 m long (along dip), commonly share composite basal erosion surfaces. Numerous scour fills are recognized over thin intervals (< 4m) along 100-200 m depositional dip, indicating limited aggradation and preservation potential for the bedforms. It is likely that cyclic steps are common in strata deposited on high gradient submarine slopes. Evidence for updip-migrating cyclic step deposits inform a revised interpretation

Conclusive identification of quantum channels via monogamy of quantum correlations

NASA Astrophysics Data System (ADS)

Kumar, Asutosh; Singha Roy, Sudipto; Pal, Amit Kumar; Prabhu, R.; Sen(De), Aditi; Sen, Ujjwal

2016-10-01

We investigate the action of global noise and local channels, namely, amplitude-damping, phase-damping, and depolarizing channels, on monogamy of quantum correlations, such as negativity and quantum discord, in three-qubit systems. We discuss the monotonic and non-monotonic variation, and robustness of the monogamy scores. By using monogamy scores, we propose a two-step protocol to conclusively identify the noise applied to the quantum system, by using generalized Greenberger-Horne-Zeilinger and generalized W states as resource states. We discuss a possible generalization of the results to higher number of parties.

High-resolution swath interferometric data collected within Muskeget Channel, Massachusetts

USGS Publications Warehouse

Pendleton, Elizabeth A.; Denny, Jane F.; Danforth, William W.; Baldwin, Wayne E.; Irwin, Barry J.

2014-01-01

Swath interferometric bathymetery data were collected within and around Muskeget Channel and along select nearshore areas south and east of Martha's Vineyard, Massachusetts. Data were collected aboard the U.S. Geological Survey research vessel Rafael in October and November 2010 in a collaborative effort between the U.S. Geological Survey and the Woods Hole Oceanographic Institution. This report describes the data-collection methods and -processing steps and releases the data in geospatial format. These data were collected to support an assessment of the effect on sediment transport that a tidal instream energy conversion facility would have within Muskeget Channel. Baseline bathymetry data were obtained for the Muskeget Channel area, and surveys in select areas were repeated after one month to monitor sediment transport and bedform migration.

Functional reconstitution of the voltage-regulated sodium channel purified from electroplax of Electrophorus electricus

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rosenberg, R.L.

1985-01-01

The voltage-regulated NA channel is responsible for the depolarization of the excitable cell membrane during the normal action potential. This research has focused on the functional properties of the Na channel, purified from detergent extracts of electroplax membranes of the electric eel, and reconstituted into vesicles of defined phospholipid. These properties were assessed by measuring neurotoxin-modulated ion flux into the reconstituted membrane vesicles and by recording the single-channel currents of the purified channel by the patch-clamp method. The binding of tritiated tetrodotoxin (TTX) was employed as a marker for the purification of the channel. Two high-resolution fractionation steps, based onmore » molecular charge and protein size, were used to obtain a preparation that is 80% homogeneous for a large peptide of 270,000 daltons. Radiotracer /sup 22/Na/sup +/ influx into the vesicles was stimulated by veratridine and by batrachotoxin (BTX) at concentrations of 100 ..mu..M and 5 ..mu..M, respectively. The stimulation by BTX was greater than that by veratridine, and can be as much as 16-fold over control influx levels. The stimulated influx is blocked by TTX with a K/sub i/ of 35 nM, and by local anesthetics in the normal pharmacological range. Large multilamellar vesicles prepared with a freeze-thaw step are suitable for single-channel recording techniques. When excised patches of the reconstituted membranes were voltage-clamped in the absence of activating neurotoxins, voltage-dependent single-channel currents were recorded. These displayed properties similar to those from native membranes of nerve and muscle. These results indicate that the protein purified on the basis of TTX binding is a functional Na channel possessing these functional domains: the ion-selective channel, the voltage sensors controlling activation and inactivation, and the sites of action of TTX, alkaloid neurotoxins, and local anesthetics.« less

Erythrocyte ion channels in regulation of apoptosis.

PubMed

Lang, Florian; Birka, Christina; Myssina, Svetlana; Lang, Karl S; Lang, Philipp A; Tanneur, Valerie; Duranton, Christophe; Wieder, Thomas; Huber, Stephan M

2004-01-01

Erythrocytes lack mitochondria and nuclei, key organelles in the regulation of apoptosis. Until recently, erythrocytes were thus not considered subject to this type of cell death. However, exposure of erythrocytes to the Ca2+ ionophore ionomycin was shown to induce cell shrinkage, cell membrane blebbing and breakdown of phosphatidylserine asymmetry with subsequent phosphatidylserine exposure at the cell surface, all typical features of apoptosis. Further studies revealed the participation of ion channels in the regulation of erythrocyte "apoptosis." Osmotic shock, oxidative stress and energy depletion all activate a Ca2(+)-permeable non-selective cation channel in the erythrocyte cell membrane. The subsequent increase of Ca2+ concentration stimulates a scramblase leading to breakdown of cell membrane phosphatidylserine asymmetry and activates Ca2+ sensitive K+ (Gardos) channels leading to KCl loss and (further) cell shrinkage. Phosphatidylserine exposure and cell shrinkage are blunted in the nominal absence of extracellular Ca2+, in the presence of the cation channel inhibitors amiloride or ethylisopropylamiloride, at increased extracellular K+ or in the presence of the Gardos channel inhibitors clotrimazole or charybdotoxin. Thus, increase of cytosolic Ca2+ and cellular loss of K+ participate in the triggering of erythrocyte scramblase. Nevertheless, phosphatidylserine exposure is not completely abrogated in the nominal absence of Ca2+, pointing to additional Ca2(+)-independent pathways. One of those is activation of sphingomyelinase with subsequent formation of ceramide which in turn leads to stimulation of erythrocyte scramblase. The exposure of phosphatidylserine at the extracellular face of the cell membrane stimulates phagocytes to engulf the apoptotic erythrocytes. Thus, sustained activation of the cation channels eventually leads to clearance of affected erythrocytes from peripheral blood. Erythropoietin inhibits the non-selective cation channel and thus

VKCDB: voltage-gated K+ channel database updated and upgraded.

PubMed

Gallin, Warren J; Boutet, Patrick A

2011-01-01

The Voltage-gated K(+) Channel DataBase (VKCDB) (http://vkcdb.biology.ualberta.ca) makes a comprehensive set of sequence data readily available for phylogenetic and comparative analysis. The current update contains 2063 entries for full-length or nearly full-length unique channel sequences from Bacteria (477), Archaea (18) and Eukaryotes (1568), an increase from 346 solely eukaryotic entries in the original release. In addition to protein sequences for channels, corresponding nucleotide sequences of the open reading frames corresponding to the amino acid sequences are now available and can be extracted in parallel with sets of protein sequences. Channels are categorized into subfamilies by phylogenetic analysis and by using hidden Markov model analyses. Although the raw database contains a number of fragmentary, duplicated, obsolete and non-channel sequences that were collected in early steps of data collection, the web interface will only return entries that have been validated as likely K(+) channels. The retrieval function of the web interface allows retrieval of entries that contain a substantial fraction of the core structural elements of VKCs, fragmentary entries, or both. The full database can be downloaded as either a MySQL dump or as an XML dump from the web site. We have now implemented automated updates at quarterly intervals.

Ternary Kv4.2 channels recapitulate voltage-dependent inactivation kinetics of A-type K+ channels in cerebellar granule neurons.

PubMed

Amarillo, Yimy; De Santiago-Castillo, Jose A; Dougherty, Kevin; Maffie, Jonathon; Kwon, Elaine; Covarrubias, Manuel; Rudy, Bernardo

2008-04-15

Kv4 channels mediate most of the somatodendritic subthreshold operating A-type current (I(SA)) in neurons. This current plays essential roles in the regulation of spike timing, repetitive firing, dendritic integration and plasticity. Neuronal Kv4 channels are thought to be ternary complexes of Kv4 pore-forming subunits and two types of accessory proteins, Kv channel interacting proteins (KChIPs) and the dipeptidyl-peptidase-like proteins (DPPLs) DPPX (DPP6) and DPP10. In heterologous cells, ternary Kv4 channels exhibit inactivation that slows down with increasing depolarization. Here, we compared the voltage dependence of the inactivation rate of channels expressed in heterologous mammalian cells by Kv4.2 proteins with that of channels containing Kv4.2 and KChIP1, Kv4.2 and DPPX-S, or Kv4.2, KChIP1 and DPPX-S, and found that the relation between inactivation rate and membrane potential is distinct for these four conditions. Moreover, recordings from native neurons showed that the inactivation kinetics of the I(SA) in cerebellar granule neurons has voltage dependence that is remarkably similar to that of ternary Kv4 channels containing KChIP1 and DPPX-S proteins in heterologous cells. The fact that this complex and unique behaviour (among A-type K(+) currents) is observed in both the native current and the current expressed in heterologous cells by the ternary complex containing Kv4, DPPX and KChIP proteins supports the hypothesis that somatically recorded native Kv4 channels in neurons include both types of accessory protein. Furthermore, quantitative global kinetic modelling showed that preferential closed-state inactivation and a weakly voltage-dependent opening step can explain the slowing of the inactivation rate with increasing depolarization. Therefore, it is likely that preferential closed-state inactivation is the physiological mechanism that regulates the activity of both ternary Kv4 channel complexes and native I(SA)-mediating channels.

Facing Aggression: Cues Differ for Female versus Male Faces

PubMed Central

Geniole, Shawn N.; Keyes, Amanda E.; Mondloch, Catherine J.; Carré, Justin M.; McCormick, Cheryl M.

2012-01-01

The facial width-to-height ratio (face ratio), is a sexually dimorphic metric associated with actual aggression in men and with observers' judgements of aggression in male faces. Here, we sought to determine if observers' judgements of aggression were associated with the face ratio in female faces. In three studies, participants rated photographs of female and male faces on aggression, femininity, masculinity, attractiveness, and nurturing. In Studies 1 and 2, for female and male faces, judgements of aggression were associated with the face ratio even when other cues in the face related to masculinity were controlled statistically. Nevertheless, correlations between the face ratio and judgements of aggression were smaller for female than for male faces (F1,36 = 7.43, p = 0.01). In Study 1, there was no significant relationship between judgements of femininity and of aggression in female faces. In Study 2, the association between judgements of masculinity and aggression was weaker in female faces than for male faces in Study 1. The weaker association in female faces may be because aggression and masculinity are stereotypically male traits. Thus, in Study 3, observers rated faces on nurturing (a stereotypically female trait) and on femininity. Judgements of nurturing were associated with femininity (positively) and masculinity (negatively) ratings in both female and male faces. In summary, the perception of aggression differs in female versus male faces. The sex difference was not simply because aggression is a gendered construct; the relationships between masculinity/femininity and nurturing were similar for male and female faces even though nurturing is also a gendered construct. Masculinity and femininity ratings are not associated with aggression ratings nor with the face ratio for female faces. In contrast, all four variables are highly inter-correlated in male faces, likely because these cues in male faces serve as “honest signals”. PMID:22276184

Facing aggression: cues differ for female versus male faces.

PubMed

Geniole, Shawn N; Keyes, Amanda E; Mondloch, Catherine J; Carré, Justin M; McCormick, Cheryl M

2012-01-01

The facial width-to-height ratio (face ratio), is a sexually dimorphic metric associated with actual aggression in men and with observers' judgements of aggression in male faces. Here, we sought to determine if observers' judgements of aggression were associated with the face ratio in female faces. In three studies, participants rated photographs of female and male faces on aggression, femininity, masculinity, attractiveness, and nurturing. In Studies 1 and 2, for female and male faces, judgements of aggression were associated with the face ratio even when other cues in the face related to masculinity were controlled statistically. Nevertheless, correlations between the face ratio and judgements of aggression were smaller for female than for male faces (F(1,36) = 7.43, p = 0.01). In Study 1, there was no significant relationship between judgements of femininity and of aggression in female faces. In Study 2, the association between judgements of masculinity and aggression was weaker in female faces than for male faces in Study 1. The weaker association in female faces may be because aggression and masculinity are stereotypically male traits. Thus, in Study 3, observers rated faces on nurturing (a stereotypically female trait) and on femininity. Judgements of nurturing were associated with femininity (positively) and masculinity (negatively) ratings in both female and male faces. In summary, the perception of aggression differs in female versus male faces. The sex difference was not simply because aggression is a gendered construct; the relationships between masculinity/femininity and nurturing were similar for male and female faces even though nurturing is also a gendered construct. Masculinity and femininity ratings are not associated with aggression ratings nor with the face ratio for female faces. In contrast, all four variables are highly inter-correlated in male faces, likely because these cues in male faces serve as "honest signals".

Atomic force microscopic study of step bunching and macrostep formation during the growth of L-arginine phosphate monohydrate single crystals

NASA Astrophysics Data System (ADS)

Sangwal, K.; Torrent-Burgues, J.; Sanz, F.; Gorostiza, P.

1997-02-01

The experimental results of the formation of step bunches and macrosteps on the {100} face of L-arginine phosphate monohydrate crystals grown from aqueous solutions at different supersaturations studied by using atomic force microscopy are described and discussed. It was observed that (1) the step height does not remain constant with increasing time but fluctuates within a particular range of heights, which depends on the region of step bunches, (2) the maximum height and the slope of bunched steps increases with growth time as well as supersaturation used for growth, and that (3) the slope of steps of relatively small heights is usually low with a value of about 8° and does not depend on the region of formation of step bunches, but the slope of steps of large heights is up to 21°. Analysis of the experimental results showed that (1) at a particular value of supersaturation the ratio of the average step height to the average step spacing is a constant, suggesting that growth of the {100} face of L-arginine phosphate monohydrate crystals occurs by direct integration of growth entities to growth steps, and that (2) the formation of step bunches and macrosteps follows the dynamic theory of faceting, advanced by Vlachos et al.

Potassium Channels in Peripheral Pain Pathways: Expression, Function and Therapeutic Potential

PubMed Central

Du, Xiaona; Gamper, Nikita

2013-01-01

Electrical excitation of peripheral somatosensory nerves is a first step in generation of most pain signals in mammalian nervous system. Such excitation is controlled by an intricate set of ion channels that are coordinated to produce a degree of excitation that is proportional to the strength of the external stimulation. However, in many disease states this coordination is disrupted resulting in deregulated peripheral excitability which, in turn, may underpin pathological pain states (i.e. migraine, neuralgia, neuropathic and inflammatory pains). One of the major groups of ion channels that are essential for controlling neuronal excitability is potassium channel family and, hereby, the focus of this review is on the K+ channels in peripheral pain pathways. The aim of the review is threefold. First, we will discuss current evidence for the expression and functional role of various K+ channels in peripheral nociceptive fibres. Second, we will consider a hypothesis suggesting that reduced functional activity of K+ channels within peripheral nociceptive pathways is a general feature of many types of pain. Third, we will evaluate the perspectives of pharmacological enhancement of K+ channels in nociceptive pathways as a strategy for new analgesic drug design. PMID:24396338

Communication, compassion, and computers: Adolescents' and adults' evaluations of online and face-to-face deception.

PubMed

O'Rourke, Sean; Eskritt, Michelle; Bosacki, Sandra

2018-06-01

We explored Canadian adolescents', emergent adults', and adults' understandings of deception in computer mediated communication (CMC) compared to face to face (FtF). Participants between 13 and 50 years read vignettes of different types of questionable behaviour that occurred online or in real life, and were asked to judge whether deception was involved, and the acceptability of the behaviour. Age groups evaluated deception similarly; however, adolescents held slightly different views from adults about what constitutes deception, suggesting that the understanding of deception continues to develop into adulthood. Furthermore, CMC behaviour was rated as more deceptive than FtF in general, and participants scoring higher on compassion perceived vignettes to be more deceptive. This study is a step towards better understanding the relationships between perceptions of deception across adolescence into adulthood, mode of communication, and compassion, and may have implications for how adults communicate with youth about deception in CMC and FtF contexts. Copyright © 2018 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

Steps wandering on the lysozyme and KDP crystals during growth in solution

NASA Astrophysics Data System (ADS)

Rashkovich, L. N.; Chernevich, T. G.; Gvozdev, N. V.; Shustin, O. A.; Yaminsky, I. V.

2001-10-01

We have applied atomic force microscopy for the study in solution of time evolution of step roughness on the crystal faces with high (pottasium dihydrophosphate: KDP) and low (lysozyme) density of kinks. It was found that the roughness increases with time revealing the time dependence as t1/4. Step velocity does not depend upon distance between steps, that is why the experimental data were interpreted on the basis of Voronkov theory, which assume, that the attachment and detachment of building units in the kinks is major limitation for crystal growth. In the frame of this theoretical model the calculation of material parameters is performed.

Intracellular zinc activates KCNQ channels by reducing their dependence on phosphatidylinositol 4,5-bisphosphate

PubMed Central

Gao, Haixia; Boillat, Aurélien; Huang, Dongyang; Liang, Ce; Peers, Chris

2017-01-01

M-type (Kv7, KCNQ) potassium channels are proteins that control the excitability of neurons and muscle cells. Many physiological and pathological mechanisms of excitation operate via the suppression of M channel activity or expression. Conversely, pharmacological augmentation of M channel activity is a recognized strategy for the treatment of hyperexcitability disorders such as pain and epilepsy. However, physiological mechanisms resulting in M channel potentiation are rare. Here we report that intracellular free zinc directly and reversibly augments the activity of recombinant and native M channels. This effect is mechanistically distinct from the known redox-dependent KCNQ channel potentiation. Interestingly, the effect of zinc cannot be attributed to a single histidine- or cysteine-containing zinc-binding site within KCNQ channels. Instead, zinc dramatically reduces KCNQ channel dependence on its obligatory physiological activator, phosphatidylinositol 4,5-bisphosphate (PIP2). We hypothesize that zinc facilitates interactions of the lipid-facing interface of a KCNQ protein with the inner leaflet of the plasma membrane in a way similar to that promoted by PIP2. Because zinc is increasingly recognized as a ubiquitous intracellular second messenger, this discovery might represent a hitherto unknown native pathway of M channel modulation and provide a fresh strategy for the design of M channel activators for therapeutic purposes. PMID:28716904

Intracellular zinc activates KCNQ channels by reducing their dependence on phosphatidylinositol 4,5-bisphosphate.

PubMed

Gao, Haixia; Boillat, Aurélien; Huang, Dongyang; Liang, Ce; Peers, Chris; Gamper, Nikita

2017-08-01

M-type (Kv7, KCNQ) potassium channels are proteins that control the excitability of neurons and muscle cells. Many physiological and pathological mechanisms of excitation operate via the suppression of M channel activity or expression. Conversely, pharmacological augmentation of M channel activity is a recognized strategy for the treatment of hyperexcitability disorders such as pain and epilepsy. However, physiological mechanisms resulting in M channel potentiation are rare. Here we report that intracellular free zinc directly and reversibly augments the activity of recombinant and native M channels. This effect is mechanistically distinct from the known redox-dependent KCNQ channel potentiation. Interestingly, the effect of zinc cannot be attributed to a single histidine- or cysteine-containing zinc-binding site within KCNQ channels. Instead, zinc dramatically reduces KCNQ channel dependence on its obligatory physiological activator, phosphatidylinositol 4,5-bisphosphate (PIP 2 ). We hypothesize that zinc facilitates interactions of the lipid-facing interface of a KCNQ protein with the inner leaflet of the plasma membrane in a way similar to that promoted by PIP 2 Because zinc is increasingly recognized as a ubiquitous intracellular second messenger, this discovery might represent a hitherto unknown native pathway of M channel modulation and provide a fresh strategy for the design of M channel activators for therapeutic purposes.

Cation Selectivity in Biological Cation Channels Using Experimental Structural Information and Statistical Mechanical Simulation.

PubMed

Finnerty, Justin John; Peyser, Alexander; Carloni, Paolo

2015-01-01

Cation selective channels constitute the gate for ion currents through the cell membrane. Here we present an improved statistical mechanical model based on atomistic structural information, cation hydration state and without tuned parameters that reproduces the selectivity of biological Na+ and Ca2+ ion channels. The importance of the inclusion of step-wise cation hydration in these results confirms the essential role partial dehydration plays in the bacterial Na+ channels. The model, proven reliable against experimental data, could be straightforwardly used for designing Na+ and Ca2+ selective nanopores.

Cation Selectivity in Biological Cation Channels Using Experimental Structural Information and Statistical Mechanical Simulation

PubMed Central

Finnerty, Justin John

2015-01-01

Cation selective channels constitute the gate for ion currents through the cell membrane. Here we present an improved statistical mechanical model based on atomistic structural information, cation hydration state and without tuned parameters that reproduces the selectivity of biological Na+ and Ca2+ ion channels. The importance of the inclusion of step-wise cation hydration in these results confirms the essential role partial dehydration plays in the bacterial Na+ channels. The model, proven reliable against experimental data, could be straightforwardly used for designing Na+ and Ca2+ selective nanopores. PMID:26460827

Permeation Mechanisms in the TMEM16B Calcium-Activated Chloride Channels

PubMed Central

2017-01-01

TMEM16A and TMEM16B encode for Ca2+-activated Cl− channels (CaCC) and are expressed in many cell types and play a relevant role in many physiological processes. Here, I performed a site-directed mutagenesis study to understand the molecular mechanisms of ion permeation of TMEM16B. I mutated two positive charged residues R573 and K540, respectively located at the entrance and inside the putative channel pore and I measured the properties of wild-type and mutant TMEM16B channels expressed in HEK-293 cells using whole-cell and excised inside-out patch clamp experiments. I found evidence that R573 and K540 control the ion permeability of TMEM16B depending both on which side of the membrane the ion substitution occurs and on the level of channel activation. Moreover, these residues contribute to control blockage or activation by permeant anions. Finally, R573 mutation abolishes the anomalous mole fraction effect observed in the presence of a permeable anion and it alters the apparent Ca2+-sensitivity of the channel. These findings indicate that residues facing the putative channel pore are responsible both for controlling the ion selectivity and the gating of the channel, providing an initial understanding of molecular mechanism of ion permeation in TMEM16B. PMID:28046119

Tryptophan Scanning Reveals Dense Packing of Connexin Transmembrane Domains in Gap Junction Channels Composed of Connexin32.

PubMed

Brennan, Matthew J; Karcz, Jennifer; Vaughn, Nicholas R; Woolwine-Cunningham, Yvonne; DePriest, Adam D; Escalona, Yerko; Perez-Acle, Tomas; Skerrett, I Martha

2015-07-10

Tryptophan was substituted for residues in all four transmembrane domains of connexin32. Function was assayed using dual cell two-electrode voltage clamp after expression in Xenopus oocytes. Tryptophan substitution was poorly tolerated in all domains, with the greatest impact in TM1 and TM4. For instance, in TM1, 15 substitutions were made, six abolished coupling and five others significantly reduced function. Only TM2 and TM3 included a distinct helical face that lacked sensitivity to tryptophan substitution. Results were visualized on a comparative model of Cx32 hemichannel. In this model, a region midway through the membrane appears highly sensitive to tryptophan substitution and includes residues Arg-32, Ile-33, Met-34, and Val-35. In the modeled channel, pore-facing regions of TM1 and TM2 were highly sensitive to tryptophan substitution, whereas the lipid-facing regions of TM3 and TM4 were variably tolerant. Residues facing a putative intracellular water pocket (the IC pocket) were also highly sensitive to tryptophan substitution. Although future studies will be required to separate trafficking-defective mutants from those that alter channel function, a subset of interactions important for voltage gating was identified. Interactions important for voltage gating occurred mainly in the mid-region of the channel and focused on TM1. To determine whether results could be extrapolated to other connexins, TM1 of Cx43 was scanned revealing similar but not identical sensitivity to TM1 of Cx32. © 2015 by The American Society for Biochemistry and Molecular Biology, Inc.

The many faces of research on face perception.

PubMed

Little, Anthony C; Jones, Benedict C; DeBruine, Lisa M

2011-06-12

Face perception is fundamental to human social interaction. Many different types of important information are visible in faces and the processes and mechanisms involved in extracting this information are complex and can be highly specialized. The importance of faces has long been recognized by a wide range of scientists. Importantly, the range of perspectives and techniques that this breadth has brought to face perception research has, in recent years, led to many important advances in our understanding of face processing. The articles in this issue on face perception each review a particular arena of interest in face perception, variously focusing on (i) the social aspects of face perception (attraction, recognition and emotion), (ii) the neural mechanisms underlying face perception (using brain scanning, patient data, direct stimulation of the brain, visual adaptation and single-cell recording), and (iii) comparative aspects of face perception (comparing adult human abilities with those of chimpanzees and children). Here, we introduce the central themes of the issue and present an overview of the articles.

Perceived safety and biomechanical stress to the lower limbs when stepping down from fire fighting vehicles.

PubMed

Giguère, Denis; Marchand, Denis

2005-01-01

Injuries related to emergency vehicles represent 19% of compensated work accidents for fire fighters, 37% of which occur while stepping down from their vehicles. This study compared the impact forces, the use of upper limbs and the perception of danger of fire fighters as they step down from five different locations on fire trucks. The results show that stepping down from the crew cab facing the street produces impact forces averaging 3.2 times the subject's body weight, but is also perceived as the safest way to descend in one of the two groups of fire fighters that participated in the study. Stepping down from the same location, but facing the truck, produced significantly less impact force and a better distribution of the energy over time. This may be achieved through better control of the descending leg, ankle flexion, and the use of grab bars. A re-design of the access to emergency vehicles should take into account both the safety needs and reduction in biomechanical stress of fire fighters.

FRONT RIGHT OBLIQUE VIEW, SHOWING FRONT WALK/STEPS AND ROYAL PALM ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

FRONT RIGHT OBLIQUE VIEW, SHOWING FRONT WALK/STEPS AND ROYAL PALM IN FOREGROUND. VIEW FACING NORTH - Camp H.M. Smith and Navy Public Works Center Manana Title VII (Capehart) Housing, Four-Bedroom, Single-Family Type 10, Birch Circle, Elm Drive, Elm Circle, and Date Drive, Pearl City, Honolulu County, HI

Face-space: A unifying concept in face recognition research.

PubMed

Valentine, Tim; Lewis, Michael B; Hills, Peter J

2016-10-01

The concept of a multidimensional psychological space, in which faces can be represented according to their perceived properties, is fundamental to the modern theorist in face processing. Yet the idea was not clearly expressed until 1991. The background that led to the development of face-space is explained, and its continuing influence on theories of face processing is discussed. Research that has explored the properties of the face-space and sought to understand caricature, including facial adaptation paradigms, is reviewed. Face-space as a theoretical framework for understanding the effect of ethnicity and the development of face recognition is evaluated. Finally, two applications of face-space in the forensic setting are discussed. From initially being presented as a model to explain distinctiveness, inversion, and the effect of ethnicity, face-space has become a central pillar in many aspects of face processing. It is currently being developed to help us understand adaptation effects with faces. While being in principle a simple concept, face-space has shaped, and continues to shape, our understanding of face perception.

Exterior structural composite panels with southern pine veneer faces and cores of southern hardwood flakes

Treesearch

C. -Y. Hse

1976-01-01

One-half-inch-thick, 8tructural exterior composite panels of various constructions were made in a one-step process, with faces of eouthern pine veneer and corea of mixed southern hardwood flakes. The flakes were precisely machined to be 3/8-inch wide, 3 inches long and 0.015 inch thick. Two veneer, cross-laminated on each face over an oriented flake core, yielded the...

Regulation of Epithelial Sodium Transport via Epithelial Na+ Channel

PubMed Central

Marunaka, Yoshinori; Niisato, Naomi; Taruno, Akiyuki; Ohta, Mariko; Miyazaki, Hiroaki; Hosogi, Shigekuni; Nakajima, Ken-ichi; Kusuzaki, Katsuyuki; Ashihara, Eishi; Nishio, Kyosuke; Iwasaki, Yoshinobu; Nakahari, Takashi; Kubota, Takahiro

2011-01-01

Renal epithelial Na+ transport plays an important role in homeostasis of our body fluid content and blood pressure. Further, the Na+ transport in alveolar epithelial cells essentially controls the amount of alveolar fluid that should be kept at an appropriate level for normal gas exchange. The epithelial Na+ transport is generally mediated through two steps: (1) the entry step of Na+ via epithelial Na+ channel (ENaC) at the apical membrane and (2) the extrusion step of Na+ via the Na+, K+-ATPase at the basolateral membrane. In general, the Na+ entry via ENaC is the rate-limiting step. Therefore, the regulation of ENaC plays an essential role in control of blood pressure and normal gas exchange. In this paper, we discuss two major factors in ENaC regulation: (1) activity of individual ENaC and (2) number of ENaC located at the apical membrane. PMID:22028593

Segmentation of human face using gradient-based approach

NASA Astrophysics Data System (ADS)

Baskan, Selin; Bulut, M. Mete; Atalay, Volkan

2001-04-01

This paper describes a method for automatic segmentation of facial features such as eyebrows, eyes, nose, mouth and ears in color images. This work is an initial step for wide range of applications based on feature-based approaches, such as face recognition, lip-reading, gender estimation, facial expression analysis, etc. Human face can be characterized by its skin color and nearly elliptical shape. For this purpose, face detection is performed using color and shape information. Uniform illumination is assumed. No restrictions on glasses, make-up, beard, etc. are imposed. Facial features are extracted using the vertically and horizontally oriented gradient projections. The gradient of a minimum with respect to its neighbor maxima gives the boundaries of a facial feature. Each facial feature has a different horizontal characteristic. These characteristics are derived by extensive experimentation with many face images. Using fuzzy set theory, the similarity between the candidate and the feature characteristic under consideration is calculated. Gradient-based method is accompanied by the anthropometrical information, for robustness. Ear detection is performed using contour-based shape descriptors. This method detects the facial features and circumscribes each facial feature with the smallest rectangle possible. AR database is used for testing. The developed method is also suitable for real-time systems.

3D face analysis by using Mesh-LBP feature

NASA Astrophysics Data System (ADS)

Wang, Haoyu; Yang, Fumeng; Zhang, Yuming; Wu, Congzhong

2017-11-01

Objective: Face Recognition is one of the widely application of image processing. Corresponding two-dimensional limitations, such as the pose and illumination changes, to a certain extent restricted its accurate rate and further development. How to overcome the pose and illumination changes and the effects of self-occlusion is the research hotspot and difficulty, also attracting more and more domestic and foreign experts and scholars to study it. 3D face recognition fusing shape and texture descriptors has become a very promising research direction. Method: Our paper presents a 3D point cloud based on mesh local binary pattern grid (Mesh-LBP), then feature extraction for 3D face recognition by fusing shape and texture descriptors. 3D Mesh-LBP not only retains the integrity of the 3D geometry, is also reduces the need for recognition process of normalization steps, because the triangle Mesh-LBP descriptor is calculated on 3D grid. On the other hand, in view of multi-modal consistency in face recognition advantage, construction of LBP can fusing shape and texture information on Triangular Mesh. In this paper, some of the operators used to extract Mesh-LBP, Such as the normal vectors of the triangle each face and vertex, the gaussian curvature, the mean curvature, laplace operator and so on. Conclusion: First, Kinect devices obtain 3D point cloud face, after the pretreatment and normalization, then transform it into triangular grid, grid local binary pattern feature extraction from face key significant parts of face. For each local face, calculate its Mesh-LBP feature with Gaussian curvature, mean curvature laplace operator and so on. Experiments on the our research database, change the method is robust and high recognition accuracy.

Changes in the expression of potassium channels during mouse T cell development

PubMed Central

1986-01-01

In this report we have combined the whole-cell electrophysiological recording technique with flow microfluorometry to isolate phenotypically defined thymocytes and T lymphocytes. Results obtained showed that J11d-/Lyt-2-/L3T4- cells express none or very few delayed rectifier K+ channels, whereas most other Lyt-2-/L3T4- cells, as well as typical cortical thymocytes (Lyt-2+/L3T4+), do express K+ channels. Mature (Lyt-2+/L3T4- or Lyt-2-/L3T4+) thymocytes, which are heterogeneous for J11d expression, were also found to be heterogeneous for K+ channel expression. Consistent with this finding was the observation that the cortisone-resistant subpopulation of thymocytes, which express low levels of J11d, were enriched for cells expressing low levels of K+ channels. Mature phenotype peripheral T lymphocytes expressed very low levels of K+ channels, but upon activation with Con A were found to express high levels of K+ channels. The results suggest that K+ channel expression in T cells is developmentally regulated. Increased expression of the channel is induced in response to mitogenic signals throughout the T cell lineage. Expression of the channel, therefore, serves as a useful marker in defining steps in the T cell differentiation pathway. PMID:2431091

Modeling human faces with multi-image photogrammetry

NASA Astrophysics Data System (ADS)

D'Apuzzo, Nicola

2002-03-01

Modeling and measurement of the human face have been increasing by importance for various purposes. Laser scanning, coded light range digitizers, image-based approaches and digital stereo photogrammetry are the used methods currently employed in medical applications, computer animation, video surveillance, teleconferencing and virtual reality to produce three dimensional computer models of the human face. Depending on the application, different are the requirements. Ours are primarily high accuracy of the measurement and automation in the process. The method presented in this paper is based on multi-image photogrammetry. The equipment, the method and results achieved with this technique are here depicted. The process is composed of five steps: acquisition of multi-images, calibration of the system, establishment of corresponding points in the images, computation of their 3-D coordinates and generation of a surface model. The images captured by five CCD cameras arranged in front of the subject are digitized by a frame grabber. The complete system is calibrated using a reference object with coded target points, which can be measured fully automatically. To facilitate the establishment of correspondences in the images, texture in the form of random patterns can be projected from two directions onto the face. The multi-image matching process, based on a geometrical constrained least squares matching algorithm, produces a dense set of corresponding points in the five images. Neighborhood filters are then applied on the matching results to remove the errors. After filtering the data, the three-dimensional coordinates of the matched points are computed by forward intersection using the results of the calibration process; the achieved mean accuracy is about 0.2 mm in the sagittal direction and about 0.1 mm in the lateral direction. The last step of data processing is the generation of a surface model from the point cloud and the application of smooth filters. Moreover, a

Seeing faces is necessary for face-domain formation.

PubMed

Arcaro, Michael J; Schade, Peter F; Vincent, Justin L; Ponce, Carlos R; Livingstone, Margaret S

2017-10-01

Here we report that monkeys raised without exposure to faces did not develop face domains, but did develop domains for other categories and did show normal retinotopic organization, indicating that early face deprivation leads to a highly selective cortical processing deficit. Therefore, experience must be necessary for the formation (or maintenance) of face domains. Gaze tracking revealed that control monkeys looked preferentially at faces, even at ages prior to the emergence of face domains, but face-deprived monkeys did not, indicating that face looking is not innate. A retinotopic organization is present throughout the visual system at birth, so selective early viewing behavior could bias category-specific visual responses toward particular retinotopic representations, thereby leading to domain formation in stereotyped locations in inferotemporal cortex, without requiring category-specific templates or biases. Thus, we propose that environmental importance influences viewing behavior, viewing behavior drives neuronal activity, and neuronal activity sculpts domain formation.

Neurocognitive mechanisms of gaze-expression interactions in face processing and social attention

PubMed Central

Graham, Reiko; LaBar, Kevin S.

2012-01-01

The face conveys a rich source of non-verbal information used during social communication. While research has revealed how specific facial channels such as emotional expression are processed, little is known about the prioritization and integration of multiple cues in the face during dyadic exchanges. Classic models of face perception have emphasized the segregation of dynamic versus static facial features along independent information processing pathways. Here we review recent behavioral and neuroscientific evidence suggesting that within the dynamic stream, concurrent changes in eye gaze and emotional expression can yield early independent effects on face judgments and covert shifts of visuospatial attention. These effects are partially segregated within initial visual afferent processing volleys, but are subsequently integrated in limbic regions such as the amygdala or via reentrant visual processing volleys. This spatiotemporal pattern may help to resolve otherwise perplexing discrepancies across behavioral studies of emotional influences on gaze-directed attentional cueing. Theoretical explanations of gaze-expression interactions are discussed, with special consideration of speed-of-processing (discriminability) and contextual (ambiguity) accounts. Future research in this area promises to reveal the mental chronometry of face processing and interpersonal attention, with implications for understanding how social referencing develops in infancy and is impaired in autism and other disorders of social cognition. PMID:22285906

Finding Hope in the Face-to-Face.

PubMed

Edgoose, Jennifer Y C; Edgoose, Julian M

2017-05-01

What does it mean to look into the face of a patient who looks back? Face-to-face encounters are at the heart of the patient-clinician relationship but their singular significance is often lost amid the demands of today's high-tech, metric-driven health care systems. Using the framework provided by the philosopher and Holocaust survivor Emmanuel Levinas, the authors explore the unique responsibility and potential for hope found only in face-to-face encounters. Revisiting this most fundamental attribute of medicine is likely our greatest chance to reclaim who we are as clinicians and why we do what we do. © 2017 Annals of Family Medicine, Inc.

SPAR-H Step-by-Step Guidance

DOE Office of Scientific and Technical Information (OSTI.GOV)

W. J. Galyean; A. M. Whaley; D. L. Kelly

This guide provides step-by-step guidance on the use of the SPAR-H method for quantifying Human Failure Events (HFEs). This guide is intended to be used with the worksheets provided in: 'The SPAR-H Human Reliability Analysis Method,' NUREG/CR-6883, dated August 2005. Each step in the process of producing a Human Error Probability (HEP) is discussed. These steps are: Step-1, Categorizing the HFE as Diagnosis and/or Action; Step-2, Rate the Performance Shaping Factors; Step-3, Calculate PSF-Modified HEP; Step-4, Accounting for Dependence, and; Step-5, Minimum Value Cutoff. The discussions on dependence are extensive and include an appendix that describes insights obtained from themore » psychology literature.« less

Composite faces are not (necessarily) processed coactively: A test using systems factorial technology and logical-rule models.

PubMed

Cheng, Xue Jun; McCarthy, Callum J; Wang, Tony S L; Palmeri, Thomas J; Little, Daniel R

2018-06-01

Upright faces are thought to be processed more holistically than inverted faces. In the widely used composite face paradigm, holistic processing is inferred from interference in recognition performance from a to-be-ignored face half for upright and aligned faces compared with inverted or misaligned faces. We sought to characterize the nature of holistic processing in composite faces in computational terms. We use logical-rule models (Fifić, Little, & Nosofsky, 2010) and Systems Factorial Technology (Townsend & Nozawa, 1995) to examine whether composite faces are processed through pooling top and bottom face halves into a single processing channel-coactive processing-which is one common mechanistic definition of holistic processing. By specifically operationalizing holistic processing as the pooling of features into a single decision process in our task, we are able to distinguish it from other processing models that may underlie composite face processing. For instance, a failure of selective attention might result even when top and bottom components of composite faces are processed in serial or in parallel without processing the entire face coactively. Our results show that performance is best explained by a mixture of serial and parallel processing architectures across all 4 upright and inverted, aligned and misaligned face conditions. The results indicate multichannel, featural processing of composite faces in a manner inconsistent with the notion of coactivity. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

Seeing faces is necessary for face-patch formation

PubMed Central

Arcaro, Michael J.; Schade, Peter F.; Vincent, Justin L.; Ponce, Carlos R.; Livingstone, Margaret S.

2017-01-01

Here we report that monkeys raised without exposure to faces did not develop face patches, but did develop domains for other categories, and did show normal retinotopic organization, indicating that early face deprivation leads to a highly selective cortical processing deficit. Therefore experience must be necessary for the formation, or maintenance, of face domains. Gaze tracking revealed that control monkeys looked preferentially at faces, even at ages prior to the emergence of face patches, but face-deprived monkeys did not, indicating that face looking is not innate. A retinotopic organization is present throughout the visual system at birth, so selective early viewing behavior could bias category-specific visual responses towards particular retinotopic representations, thereby leading to domain formation in stereotyped locations in IT, without requiring category-specific templates or biases. Thus we propose that environmental importance influences viewing behavior, viewing behavior drives neuronal activity, and neuronal activity sculpts domain formation. PMID:28869581

Bayesian Face Recognition and Perceptual Narrowing in Face-Space

PubMed Central

Balas, Benjamin

2012-01-01

During the first year of life, infants’ face recognition abilities are subject to “perceptual narrowing,” the end result of which is that observers lose the ability to distinguish previously discriminable faces (e.g. other-race faces) from one another. Perceptual narrowing has been reported for faces of different species and different races, in developing humans and primates. Though the phenomenon is highly robust and replicable, there have been few efforts to model the emergence of perceptual narrowing as a function of the accumulation of experience with faces during infancy. The goal of the current study is to examine how perceptual narrowing might manifest as statistical estimation in “face space,” a geometric framework for describing face recognition that has been successfully applied to adult face perception. Here, I use a computer vision algorithm for Bayesian face recognition to study how the acquisition of experience in face space and the presence of race categories affect performance for own and other-race faces. Perceptual narrowing follows from the establishment of distinct race categories, suggesting that the acquisition of category boundaries for race is a key computational mechanism in developing face expertise. PMID:22709406

Use-dependent activation of neuronal Kv1.2 channel complexes.

PubMed

Baronas, Victoria A; McGuinness, Brandon R; Brigidi, G Stefano; Gomm Kolisko, Rachel N; Vilin, Yury Y; Kim, Robin Y; Lynn, Francis C; Bamji, Shernaz X; Yang, Runying; Kurata, Harley T

2015-02-25

In excitable cells, ion channels are frequently challenged by repetitive stimuli, and their responses shape cellular behavior by regulating the duration and termination of bursts of action potentials. We have investigated the behavior of Shaker family voltage-gated potassium (Kv) channels subjected to repetitive stimuli, with a particular focus on Kv1.2. Genetic deletion of this subunit results in complete mortality within 2 weeks of birth in mice, highlighting a critical physiological role for Kv1.2. Kv1.2 channels exhibit a unique property described previously as "prepulse potentiation," in which activation by a depolarizing step facilitates activation in a subsequent pulse. In this study, we demonstrate that this property enables Kv1.2 channels to exhibit use-dependent activation during trains of very brief depolarizations. Also, Kv subunits usually assemble into heteromeric channels in the central nervous system, generating diversity of function and sensitivity to signaling mechanisms. We demonstrate that other Kv1 channel types do not exhibit use-dependent activation, but this property is conferred in heteromeric channel complexes containing even a single Kv1.2 subunit. This regulatory mechanism is observed in mammalian cell lines as well as primary cultures of hippocampal neurons. Our findings illustrate that use-dependent activation is a unique property of Kv1.2 that persists in heteromeric channel complexes and may influence function of hippocampal neurons. Copyright © 2015 the authors 0270-6474/15/353515-10$15.00/0.

Contributions of individual face features to face discrimination.

PubMed

Logan, Andrew J; Gordon, Gael E; Loffler, Gunter

2017-08-01

Faces are highly complex stimuli that contain a host of information. Such complexity poses the following questions: (a) do observers exhibit preferences for specific information? (b) how does sensitivity to individual face parts compare? These questions were addressed by quantifying sensitivity to different face features. Discrimination thresholds were determined for synthetic faces under the following conditions: (i) 'full face': all face features visible; (ii) 'isolated feature': single feature presented in isolation; (iii) 'embedded feature': all features visible, but only one feature modified. Mean threshold elevations for isolated features, relative to full-faces, were 0.84x, 1.08, 2.12, 3.34, 4.07 and 4.47 for head-shape, hairline, nose, mouth, eyes and eyebrows respectively. Hence, when two full faces can be discriminated at threshold, the difference between the eyes is about four times less than what is required when discriminating between isolated eyes. In all cases, sensitivity was higher when features were presented in isolation than when they were embedded within a face context (threshold elevations of 0.94x, 1.74, 2.67, 2.90, 5.94 and 9.94). This reveals a specific pattern of sensitivity to face information. Observers are between two and four times more sensitive to external than internal features. The pattern for internal features (higher sensitivity for the nose, compared to mouth, eyes and eyebrows) is consistent with lower sensitivity for those parts affected by facial dynamics (e.g. facial expressions). That isolated features are easier to discriminate than embedded features supports a holistic face processing mechanism which impedes extraction of information about individual features from full faces. Copyright © 2017 Elsevier Ltd. All rights reserved.

Successful Decoding of Famous Faces in the Fusiform Face Area

PubMed Central

Axelrod, Vadim; Yovel, Galit

2015-01-01

What are the neural mechanisms of face recognition? It is believed that the network of face-selective areas, which spans the occipital, temporal, and frontal cortices, is important in face recognition. A number of previous studies indeed reported that face identity could be discriminated based on patterns of multivoxel activity in the fusiform face area and the anterior temporal lobe. However, given the difficulty in localizing the face-selective area in the anterior temporal lobe, its role in face recognition is still unknown. Furthermore, previous studies limited their analysis to occipito-temporal regions without testing identity decoding in more anterior face-selective regions, such as the amygdala and prefrontal cortex. In the current high-resolution functional Magnetic Resonance Imaging study, we systematically examined the decoding of the identity of famous faces in the temporo-frontal network of face-selective and adjacent non-face-selective regions. A special focus has been put on the face-area in the anterior temporal lobe, which was reliably localized using an optimized scanning protocol. We found that face-identity could be discriminated above chance level only in the fusiform face area. Our results corroborate the role of the fusiform face area in face recognition. Future studies are needed to further explore the role of the more recently discovered anterior face-selective areas in face recognition. PMID:25714434

Successful decoding of famous faces in the fusiform face area.

PubMed

Axelrod, Vadim; Yovel, Galit

2015-01-01

What are the neural mechanisms of face recognition? It is believed that the network of face-selective areas, which spans the occipital, temporal, and frontal cortices, is important in face recognition. A number of previous studies indeed reported that face identity could be discriminated based on patterns of multivoxel activity in the fusiform face area and the anterior temporal lobe. However, given the difficulty in localizing the face-selective area in the anterior temporal lobe, its role in face recognition is still unknown. Furthermore, previous studies limited their analysis to occipito-temporal regions without testing identity decoding in more anterior face-selective regions, such as the amygdala and prefrontal cortex. In the current high-resolution functional Magnetic Resonance Imaging study, we systematically examined the decoding of the identity of famous faces in the temporo-frontal network of face-selective and adjacent non-face-selective regions. A special focus has been put on the face-area in the anterior temporal lobe, which was reliably localized using an optimized scanning protocol. We found that face-identity could be discriminated above chance level only in the fusiform face area. Our results corroborate the role of the fusiform face area in face recognition. Future studies are needed to further explore the role of the more recently discovered anterior face-selective areas in face recognition.

Bedrock channel reaches morphology: examples from the Northern Marche Region (Italy)

NASA Astrophysics Data System (ADS)

Tiberi, V.; di Agostino, V.; Troiani, F.; Nesci, O.; Savelli, D.

2009-04-01

The Northern Marche rivers, on account of a significant variability of their catchment geology, geodynamics and geomorphology, can be regarded as excellent natural laboratories for the study of the morphology, dynamics and evolution of bedrock channel reaches. Hence a geomorphologic study has been carried on in order to map and describe -from qualitative and quantitative point of view- some bedrock channel types of this area, to detect morphological controls at different scales (from the local scale up to the catchment one), and to assess human perturbations on the drainage systems. The study is based on detailed field surveying concerning channel shape and dynamics, floodplain configurations, slope geomorphologic processes, bedrock structure and composition. In addiction, a good aero photograph documentation dating back to the 1955 allowed a reliable reconstruction of the main evolution trends of bedrock channel reaches in the latest past. In the reported rivers the bedrock channel reaches vary in length from a few tens to hundreds of meters, and alternate with alluvial and mixed bedrock-alluvial channel reaches. In many cases specific numerical relations among geometric parameters of bedrock channels have been discovered and some similarities in both morphology and dynamics of rock-cut channels with alluvial channel reaches have been pointed out. Specifically, with regard of their morphologic arrangement, geometric parameters, and flow dynamics several bedrock channels are quite similar to step pool channels found along gravelly channel reaches. Nonetheless, along a given segment of the hydrographical network where an individual alluvial-channel pattern (e.g. a wandering) is found both upstream and downstream a rock-cut channel reach, the occurrence of this latter (e.g. planar bedrock-floored channel) simply breaks the along-stream continuity of the alluvial-bed morphology.

"A Step Away from Complacent Knowing": Reinvigorating Democracy through the Humanities

ERIC Educational Resources Information Center

Musil, Caryn McTighe

2015-01-01

"A step away from complacent knowing" argues that the humanities have long been understood as enhancing civic life and human intellectual and moral development. At moments when democratic societies seem at risk, however, such as the birth of the new US Republic, the aftermath of World War II, and in the face of an anemic…

Voltage-Dependent Gating of hERG Potassium Channels

PubMed Central

Cheng, Yen May; Claydon, Tom W.

2012-01-01

The mechanisms by which voltage-gated channels sense changes in membrane voltage and energetically couple this with opening of the ion conducting pore has been the source of significant interest. In voltage-gated potassium (Kv) channels, much of our knowledge in this area comes from Shaker-type channels, for which voltage-dependent gating is quite rapid. In these channels, activation and deactivation are associated with rapid reconfiguration of the voltage-sensing domain unit that is electromechanically coupled, via the S4–S5 linker helix, to the rate-limiting opening of an intracellular pore gate. However, fast voltage-dependent gating kinetics are not typical of all Kv channels, such as Kv11.1 (human ether-à-go-go related gene, hERG), which activates and deactivates very slowly. Compared to Shaker channels, our understanding of the mechanisms underlying slow hERG gating is much poorer. Here, we present a comparative review of the structure–function relationships underlying activation and deactivation gating in Shaker and hERG channels, with a focus on the roles of the voltage-sensing domain and the S4–S5 linker that couples voltage sensor movements to the pore. Measurements of gating current kinetics and fluorimetric analysis of voltage sensor movement are consistent with models suggesting that the hERG activation pathway contains a voltage independent step, which limits voltage sensor transitions. Constraints upon hERG voltage sensor movement may result from loose packing of the S4 helices and additional intra-voltage sensor counter-charge interactions. More recent data suggest that key amino acid differences in the hERG voltage-sensing unit and S4–S5 linker, relative to fast activating Shaker-type Kv channels, may also contribute to the increased stability of the resting state of the voltage sensor. PMID:22586397

The Background of Reduced Face Specificity of N170 in Congenital Prosopagnosia

PubMed Central

Schweinberger, Stefan R.; Vakli, Pál; Kovács, Gyula

2014-01-01

Congenital prosopagnosia is lifelong face-recognition impairment in the absence of evidence for structural brain damage. To study the neural correlates of congenital prosopagnosia, we measured the face-sensitive N170 component of the event-related potential in three members of the same family (father (56 y), son (25 y) and daughter (22 y)) and in age-matched neurotypical participants (young controls: n = 14; 24.5 y±2.1; old controls: n = 6; 57.3 y±5.4). To compare the face sensitivity of N170 in congenital prosopagnosic and neurotypical participants we measured the event-related potentials for faces and phase-scrambled random noise stimuli. In neurotypicals we found significantly larger N170 amplitude for faces compared to noise stimuli, reflecting normal early face processing. The congenital prosopagnosic participants, by contrast, showed reduced face sensitivity of the N170, and this was due to a larger than normal noise-elicited N170, rather than to a smaller face-elicited N170. Interestingly, single-trial analysis revealed that the lack of face sensitivity in congenital prosopagnosia is related to a larger oscillatory power and phase-locking in the theta frequency-band (4–7 Hz, 130–190 ms) as well as to a lower intertrial jitter of the response latency for the noise stimuli. Altogether, these results suggest that congenital prosopagnosia is due to the deficit of early, structural encoding steps of face perception in filtering between face and non-face stimuli. PMID:24983881

Instream wood in a steep headwater channel: geomorphic significance of large and small wood

NASA Astrophysics Data System (ADS)

Galia, Tomáš; Šilhán, Karel; Ruiz-Villanueva, Virginia; Tichavský, Radek

2016-04-01

Besides the well-known significance of large wood (LW), also small woody pieces (SW; here defined as pieces with dimensions at least 0.5 m length and 0.05 m diameter), can play an important role in steep narrow headwaters. We inventoried instream wood in the 0.4 km long Mazák headwater channel, Moravskoslezské Beskydy Mts, Czech Republic (2channel width by a wood, the geomorphic function of a wood (step, wood jam) and % of length of a wood in channel were assessed. The total number of inventoried instream wood was 90 LWs and 199 SWs. In addition, dendrogeomorphic dating of 36 LWs and 17 SWs was performed to obtain residence time of local instream wood and to provide some insights into its mobility. Practically all investigated pieces were European beeches (Fagus sylvatica L.); only two pieces were Norway spruces (Picea abies (L.) Karst.). First results showed an increase in the number of LWs in channel-reaches confined by the steepest adjacent hillslopes (especially at 0.15-0.20 km). Increasing downstream amount of SW most likely reflected transport processes in the stream, and the later deposition of SWs on the lowest channel gradients. Also LWs and SWs in the downstream channel-reaches were more decayed than wood presented in the upper reaches. The orientation of instream wood was connected with its length and stability, and LWs longer than 5 m were usually attached to adjacent hillslopes. Pieces longer than 2 m, which were unattached or were somehow stabilized in the channel bed, had often orientation of 0° or 337°. LWs were mostly unattached in the upstream channel-reaches, while often stabilized by adjacent hillslopes in the middle part. At 0.05-0.10 km, there were also many logs stabilized by

PT-IP-759, channel caulking tests: C Reactor

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cooke, J.P.; Russell, A.

1965-03-19

The graphite movement which has occurred at the various reactors has been characterized by two problems: (1) Crooked channels and (2) cracks and miscellaneous voids where pieces of blocks are missing. Of these problems, the cracks and voids have been the most serious in the case of ball drops. Alleviation of the crooked channels can sometimes be accomplished by graphite removal methods such as broaching, but unless some method is found to prevent the balls from entering cracks, the total effect of a ball drop would still be intolerable. Of the two methods of closing the cracks, a paste caulkingmore » procedure is anticipated to be less expensive than sleeving, both in terms of cost of the operation and the number of process tube channels which might be lost. If the VSR channel does not require drastic straightening or entry of large tooling, satisfactory caulking can be done without removal of the step plug. ``Poison`` chain may be considered as an alternative to caulking or sleeving for those outer VSR channels where the sole use of balls is for ``total control`` rather than ``speed of control.`` The objectives of this test are (1) to authorize the experimental crack filling of one or two of the VSR channels at C Reactor with a wet mixture of graphite and sugar, (2) to demonstrate the durability of this mixture in subsequent normal reactor operation, and (3) to demonstrate by testing (actual or simulated ball drops) and borescoping, that the channels are or are not again acceptable for use with the normal charge of balls.« less

Atomistic insight into the adsorption site selectivity of stepped Au(111) surfaces

NASA Astrophysics Data System (ADS)

Gaspari, Roberto; Pignedoli, Carlo A.; Fasel, Roman; Treier, Matthias; Passerone, Daniele

2010-07-01

Using classical and ab initio simulations, we study the interplay between the Au(111) surface reconstruction and monoatomic steps on a vicinal face. The experimentally observed discommensuration line patterns on a specific vicinal are reproduced and explained, and a complete description of the structure is given. An unusual atomic arrangement is shown to be responsible for the lower reactivity of hcp segments of step edges compared to the one of fcc segments. Our results provide an unprecedented understanding of the electronic and geometric properties of the complex Au(111) surface.

Cross-modal face recognition using multi-matcher face scores

NASA Astrophysics Data System (ADS)

Zheng, Yufeng; Blasch, Erik

2015-05-01

The performance of face recognition can be improved using information fusion of multimodal images and/or multiple algorithms. When multimodal face images are available, cross-modal recognition is meaningful for security and surveillance applications. For example, a probe face is a thermal image (especially at nighttime), while only visible face images are available in the gallery database. Matching a thermal probe face onto the visible gallery faces requires crossmodal matching approaches. A few such studies were implemented in facial feature space with medium recognition performance. In this paper, we propose a cross-modal recognition approach, where multimodal faces are cross-matched in feature space and the recognition performance is enhanced with stereo fusion at image, feature and/or score level. In the proposed scenario, there are two cameras for stereo imaging, two face imagers (visible and thermal images) in each camera, and three recognition algorithms (circular Gaussian filter, face pattern byte, linear discriminant analysis). A score vector is formed with three cross-matched face scores from the aforementioned three algorithms. A classifier (e.g., k-nearest neighbor, support vector machine, binomial logical regression [BLR]) is trained then tested with the score vectors by using 10-fold cross validations. The proposed approach was validated with a multispectral stereo face dataset from 105 subjects. Our experiments show very promising results: ACR (accuracy rate) = 97.84%, FAR (false accept rate) = 0.84% when cross-matching the fused thermal faces onto the fused visible faces by using three face scores and the BLR classifier.

Meta-analytic review of the development of face discrimination in infancy: Face race, face gender, infant age, and methodology moderate face discrimination.

PubMed

Sugden, Nicole A; Marquis, Alexandra R

2017-11-01

Infants show facility for discriminating between individual faces within hours of birth. Over the first year of life, infants' face discrimination shows continued improvement with familiar face types, such as own-race faces, but not with unfamiliar face types, like other-race faces. The goal of this meta-analytic review is to provide an effect size for infants' face discrimination ability overall, with own-race faces, and with other-race faces within the first year of life, how this differs with age, and how it is influenced by task methodology. Inclusion criteria were (a) infant participants aged 0 to 12 months, (b) completing a human own- or other-race face discrimination task, (c) with discrimination being determined by infant looking. Our analysis included 30 works (165 samples, 1,926 participants participated in 2,623 tasks). The effect size for infants' face discrimination was small, 6.53% greater than chance (i.e., equal looking to the novel and familiar). There was a significant difference in discrimination by race, overall (own-race, 8.18%; other-race, 3.18%) and between ages (own-race: 0- to 4.5-month-olds, 7.32%; 5- to 7.5-month-olds, 9.17%; and 8- to 12-month-olds, 7.68%; other-race: 0- to 4.5-month-olds, 6.12%; 5- to 7.5-month-olds, 3.70%; and 8- to 12-month-olds, 2.79%). Multilevel linear (mixed-effects) models were used to predict face discrimination; infants' capacity to discriminate faces is sensitive to face characteristics including race, gender, and emotion as well as the methods used, including task timing, coding method, and visual angle. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Faciotopy—A face-feature map with face-like topology in the human occipital face area

PubMed Central

Henriksson, Linda; Mur, Marieke; Kriegeskorte, Nikolaus

2015-01-01

The occipital face area (OFA) and fusiform face area (FFA) are brain regions thought to be specialized for face perception. However, their intrinsic functional organization and status as cortical areas with well-defined boundaries remains unclear. Here we test these regions for “faciotopy”, a particular hypothesis about their intrinsic functional organisation. A faciotopic area would contain a face-feature map on the cortical surface, where cortical patches represent face features and neighbouring patches represent features that are physically neighbouring in a face. The faciotopy hypothesis is motivated by the idea that face regions might develop from a retinotopic protomap and acquire their selectivity for face features through natural visual experience. Faces have a prototypical configuration of features, are usually perceived in a canonical upright orientation, and are frequently fixated in particular locations. To test the faciotopy hypothesis, we presented images of isolated face features at fixation to subjects during functional magnetic resonance imaging. The responses in V1 were best explained by low-level image properties of the stimuli. OFA, and to a lesser degree FFA, showed evidence for faciotopic organization. When a single patch of cortex was estimated for each face feature, the cortical distances between the feature patches reflected the physical distance between the features in a face. Faciotopy would be the first example, to our knowledge, of a cortical map reflecting the topology, not of a part of the organism itself (its retina in retinotopy, its body in somatotopy), but of an external object of particular perceptual significance. PMID:26235800

Faciotopy-A face-feature map with face-like topology in the human occipital face area.

PubMed

Henriksson, Linda; Mur, Marieke; Kriegeskorte, Nikolaus

2015-11-01

The occipital face area (OFA) and fusiform face area (FFA) are brain regions thought to be specialized for face perception. However, their intrinsic functional organization and status as cortical areas with well-defined boundaries remains unclear. Here we test these regions for "faciotopy", a particular hypothesis about their intrinsic functional organisation. A faciotopic area would contain a face-feature map on the cortical surface, where cortical patches represent face features and neighbouring patches represent features that are physically neighbouring in a face. The faciotopy hypothesis is motivated by the idea that face regions might develop from a retinotopic protomap and acquire their selectivity for face features through natural visual experience. Faces have a prototypical configuration of features, are usually perceived in a canonical upright orientation, and are frequently fixated in particular locations. To test the faciotopy hypothesis, we presented images of isolated face features at fixation to subjects during functional magnetic resonance imaging. The responses in V1 were best explained by low-level image properties of the stimuli. OFA, and to a lesser degree FFA, showed evidence for faciotopic organization. When a single patch of cortex was estimated for each face feature, the cortical distances between the feature patches reflected the physical distance between the features in a face. Faciotopy would be the first example, to our knowledge, of a cortical map reflecting the topology, not of a part of the organism itself (its retina in retinotopy, its body in somatotopy), but of an external object of particular perceptual significance. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

A Cytosolic Amphiphilic α-Helix Controls the Activity of the Bile Acid-sensitive Ion Channel (BASIC)*

PubMed Central

Schmidt, Axel; Löhrer, Daniel; Alsop, Richard J.; Lenzig, Pia; Oslender-Bujotzek, Adrienne; Wirtz, Monika; Rheinstädter, Maikel C.; Gründer, Stefan; Wiemuth, Dominik

2016-01-01

The bile acid-sensitive ion channel (BASIC) is a member of the degenerin/epithelial Na+ channel (Deg/ENaC) family of ion channels. It is mainly found in bile duct epithelial cells, the intestinal tract, and the cerebellum and is activated by alterations of its membrane environment. Bile acids, one class of putative physiological activators, exert their effect by changing membrane properties, leading to an opening of the channel. The physiological function of BASIC, however, is unknown. Deg/ENaC channels are characterized by a trimeric subunit composition. Each subunit is composed of two transmembrane segments, which are linked by a large extracellular domain. The termini of the channels protrude into the cytosol. Many Deg/ENaC channels contain regulatory domains and sequence motifs within their cytosolic domains. In this study, we show that BASIC contains an amphiphilic α-helical structure within its N-terminal domain. This α-helix binds to the cytosolic face of the plasma membrane and stabilizes a closed state. Truncation of this domain renders the channel hyperactive. Collectively, we identify a cytoplasmic domain, unique to BASIC, that controls channel activity via membrane interaction. PMID:27679529

A Cytosolic Amphiphilic α-Helix Controls the Activity of the Bile Acid-sensitive Ion Channel (BASIC).

PubMed

Schmidt, Axel; Löhrer, Daniel; Alsop, Richard J; Lenzig, Pia; Oslender-Bujotzek, Adrienne; Wirtz, Monika; Rheinstädter, Maikel C; Gründer, Stefan; Wiemuth, Dominik

2016-11-18

The bile acid-sensitive ion channel (BASIC) is a member of the degenerin/epithelial Na + channel (Deg/ENaC) family of ion channels. It is mainly found in bile duct epithelial cells, the intestinal tract, and the cerebellum and is activated by alterations of its membrane environment. Bile acids, one class of putative physiological activators, exert their effect by changing membrane properties, leading to an opening of the channel. The physiological function of BASIC, however, is unknown. Deg/ENaC channels are characterized by a trimeric subunit composition. Each subunit is composed of two transmembrane segments, which are linked by a large extracellular domain. The termini of the channels protrude into the cytosol. Many Deg/ENaC channels contain regulatory domains and sequence motifs within their cytosolic domains. In this study, we show that BASIC contains an amphiphilic α-helical structure within its N-terminal domain. This α-helix binds to the cytosolic face of the plasma membrane and stabilizes a closed state. Truncation of this domain renders the channel hyperactive. Collectively, we identify a cytoplasmic domain, unique to BASIC, that controls channel activity via membrane interaction. © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

Emotional Expression and Heart Rate in High-Risk Infants during the Face-To-Face/Still-Face

PubMed Central

Mattson, Whitney I.; Ekas, Naomi V.; Lambert, Brittany; Tronick, Ed; Lester, Barry M.; Messinger, Daniel S.

2013-01-01

In infants, eye constriction—the Duchenne marker—and mouth opening appear to index the intensity of both positive and negative facial expressions. We combined eye constriction and mouth opening that co-occurred with smiles and cry-faces (respectively, the prototypic expressions of infant joy and distress) to measure emotional expression intensity. Expression intensity and heart rate were measured throughout the Face-to-Face/Still Face (FFSF) in a sample of infants with prenatal cocaine exposure who were at risk for developmental difficulties. Smiles declined and cry-faces increased in the still-face episode, but the distribution of eye constriction and mouth opening in smiles and cry-faces did not differ across episodes of the FFSF. As time elapsed in the still face episode potential indices of intensity increased, cry-faces were more likely to be accompanied by eye constriction and mouth opening. During cry-faces there were also moderately stable individual differences in the quantity of eye constriction and mouth opening. Infant heart rate was higher during cry-faces and lower during smiles, but did not vary with intensity of expression or by episode. In sum, infants express more intense negative affect as the still-face progresses, but do not show clear differences in expressive intensity between episodes of the FFSF. PMID:24095807

GOM-Face: GKP, EOG, and EMG-based multimodal interface with application to humanoid robot control.

PubMed

Nam, Yunjun; Koo, Bonkon; Cichocki, Andrzej; Choi, Seungjin

2014-02-01

We present a novel human-machine interface, called GOM-Face , and its application to humanoid robot control. The GOM-Face bases its interfacing on three electric potentials measured on the face: 1) glossokinetic potential (GKP), which involves the tongue movement; 2) electrooculogram (EOG), which involves the eye movement; 3) electromyogram, which involves the teeth clenching. Each potential has been individually used for assistive interfacing to provide persons with limb motor disabilities or even complete quadriplegia an alternative communication channel. However, to the best of our knowledge, GOM-Face is the first interface that exploits all these potentials together. We resolved the interference between GKP and EOG by extracting discriminative features from two covariance matrices: a tongue-movement-only data matrix and eye-movement-only data matrix. With the feature extraction method, GOM-Face can detect four kinds of horizontal tongue or eye movements with an accuracy of 86.7% within 2.77 s. We demonstrated the applicability of the GOM-Face to humanoid robot control: users were able to communicate with the robot by selecting from a predefined menu using the eye and tongue movements.

Channel morphology and patterns of bedload transport in fluvial, formerly-glaciated, forested headwater streams of the Columbia Mountains, Canada

NASA Astrophysics Data System (ADS)

Green, Kim; Brardinoni, Francesco; Alila, Younes

2013-04-01

This study examines channel-reach morphology and bedload transport dynamics in relation to landscape structure and snowmelt hydrology in Cotton and Elk Creek, two headwater streams of the southern Columbia Mountains, Canada. Data collection is based on field surveys and GIS analysis in conjunction with a nested monitoring network of water discharge and bed load transfer. The nested monitoring network is designed to examine the effects of channel bed texture, and the influence of free-formed (i.e., boulder cascades, step pools, and riffle pools) and forced-alluvial morphologies (i.e., forced step pools) on bedload entrainment and transport. The landscape is characterized by subdued glaciated topography in which sediment is primarily supplied by bank failures and fluvial transfer dominates the channelized sediment cascade. The spatial distribution of channel types is mainly controlled by glacially imposed local slope together with availability of wood and glacigenic materials. Interestingly, downstream hydraulic geometry as well as downstream patterns of the coarse channel bed fraction and stream power are all insensitive to systematic changes of local slope along the typically stepped longitudinal profiles. An indication that the study alluvial systems are adjusted to the contemporary hydrologic and sedimentary regimes, and as such through post-LGM times have been able to compensate for the glacially-imposed boundary conditions. Stepwise multiple regression indicates that annual bedload yield is chiefly controlled by the number of peak events over threshold discharge. During such high flows, repeated destabilization of channel bed armouring and re-mobilization of sediment stored behind logjams can ensure sediment supply for bedload transport across the entire snowmelt season. In particular, channel morphology affects distinctively the variability of bed load response to hydrologic forcing. The observed spatial variability in annual bedload yield appears to correlate

Voicing on Virtual and Face to Face Discussion

ERIC Educational Resources Information Center

Yamat, Hamidah

2013-01-01

This paper presents and discusses findings of a study conducted on pre-service teachers' experiences in virtual and face to face discussions. Technology has brought learning nowadays beyond the classroom context or time zone. The learning context and process no longer rely solely on face to face communications in the presence of a teacher.…

Face to face with emotion: holistic face processing is modulated by emotional state.

PubMed

Curby, Kim M; Johnson, Kareem J; Tyson, Alyssa

2012-01-01

Negative emotions are linked with a local, rather than global, visual processing style, which may preferentially facilitate feature-based, relative to holistic, processing mechanisms. Because faces are typically processed holistically, and because social contexts are prime elicitors of emotions, we examined whether negative emotions decrease holistic processing of faces. We induced positive, negative, or neutral emotions via film clips and measured holistic processing before and after the induction: participants made judgements about cued parts of chimeric faces, and holistic processing was indexed by the interference caused by task-irrelevant face parts. Emotional state significantly modulated face-processing style, with the negative emotion induction leading to decreased holistic processing. Furthermore, self-reported change in emotional state correlated with changes in holistic processing. These results contrast with general assumptions that holistic processing of faces is automatic and immune to outside influences, and they illustrate emotion's power to modulate socially relevant aspects of visual perception.

Magnetohydrodynamic (MHD) channel corner seal

DOEpatents

Spurrier, Francis R.

1980-01-01

A corner seal for an MHD duct includes a compressible portion which contacts the duct walls and an insulating portion which contacts the electrodes, sidewall bars and insulators. The compressible portion may be a pneumatic or hydraulic gasket or an open-cell foam rubber. The insulating portion is segmented into a plurality of pieces of the same thickness as the electrodes, insulators and sidewall bars and aligned therewith, the pieces aligned with the insulator being of a different size from the pieces aligned with the electrodes and sidewall bars to create a stepped configuration along the corners of the MHD channel.

Learning Compact Binary Face Descriptor for Face Recognition.

PubMed

Lu, Jiwen; Liong, Venice Erin; Zhou, Xiuzhuang; Zhou, Jie

2015-10-01

Binary feature descriptors such as local binary patterns (LBP) and its variations have been widely used in many face recognition systems due to their excellent robustness and strong discriminative power. However, most existing binary face descriptors are hand-crafted, which require strong prior knowledge to engineer them by hand. In this paper, we propose a compact binary face descriptor (CBFD) feature learning method for face representation and recognition. Given each face image, we first extract pixel difference vectors (PDVs) in local patches by computing the difference between each pixel and its neighboring pixels. Then, we learn a feature mapping to project these pixel difference vectors into low-dimensional binary vectors in an unsupervised manner, where 1) the variance of all binary codes in the training set is maximized, 2) the loss between the original real-valued codes and the learned binary codes is minimized, and 3) binary codes evenly distribute at each learned bin, so that the redundancy information in PDVs is removed and compact binary codes are obtained. Lastly, we cluster and pool these binary codes into a histogram feature as the final representation for each face image. Moreover, we propose a coupled CBFD (C-CBFD) method by reducing the modality gap of heterogeneous faces at the feature level to make our method applicable to heterogeneous face recognition. Extensive experimental results on five widely used face datasets show that our methods outperform state-of-the-art face descriptors.

Photographic guidance for selecting flow resistance coefficients in high-gradient channels

Treesearch

Steven E. Yochum; Francesco Comiti; Ellen Wohl; Gabrielle C. L. David; Luca Mao

2014-01-01

Photographic guidance is presented to assist with the estimation of Manning’s n and Darcy-Weisbach f in high-gradient plane-bed, step-pool, and cascade channels. Reaches both with and without instream wood are included. These coefficients are necessary for the estimation of reachaverage velocity, energy loss, and...

Methods for growth of relatively large step-free SiC crystal surfaces

NASA Technical Reports Server (NTRS)

Neudeck, Philip G. (Inventor); Powell, J. Anthony (Inventor)

2002-01-01

A method for growing arrays of large-area device-size films of step-free (i.e., atomically flat) SiC surfaces for semiconductor electronic device applications is disclosed. This method utilizes a lateral growth process that better overcomes the effect of extended defects in the seed crystal substrate that limited the obtainable step-free area achievable by prior art processes. The step-free SiC surface is particularly suited for the heteroepitaxial growth of 3C (cubic) SiC, AlN, and GaN films used for the fabrication of both surface-sensitive devices (i.e., surface channel field effect transistors such as HEMT's and MOSFET's) as well as high-electric field devices (pn diodes and other solid-state power switching devices) that are sensitive to extended crystal defects.

Lightning energetics: Estimates of energy dissipation in channels, channel radii, and channel-heating risetimes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Borovsky, J.E.

1998-05-01

In this report, several lightning-channel parameters are calculated with the aid of an electrodynamic model of lightning. The electrodynamic model describes dart leaders and return strokes as electromagnetic waves that are guided along conducting lightning channels. According to the model, electrostatic energy is delivered to the channel by a leader, where it is stored around the outside of the channel; subsequently, the return stroke dissipates this locally stored energy. In this report this lightning-energy-flow scenario is developed further. Then the energy dissipated per unit length in lightning channels is calculated, where this quantity is now related to the linear chargemore » density on the channel, not to the cloud-to-ground electrostatic potential difference. Energy conservation is then used to calculate the radii of lightning channels: their initial radii at the onset of return strokes and their final radii after the channels have pressure expanded. Finally, the risetimes for channel heating during return strokes are calculated by defining an energy-storage radius around the channel and by estimating the radial velocity of energy flow toward the channel during a return stroke. In three appendices, values for the linear charge densities on lightning channels are calculated, estimates of the total length of branch channels are obtained, and values for the cloud-to-ground electrostatic potential difference are estimated. {copyright} 1998 American Geophysical Union« less

Emotional expression and heart rate in high-risk infants during the face-to-face/still-face.

PubMed

Mattson, Whitney I; Ekas, Naomi V; Lambert, Brittany; Tronick, Ed; Lester, Barry M; Messinger, Daniel S

2013-12-01

In infants, eye constriction-the Duchenne marker-and mouth opening appear to index the intensity of both positive and negative facial expressions. We combined eye constriction and mouth opening that co-occurred with smiles and cry-faces (respectively, the prototypic expressions of infant joy and distress) to measure emotional expression intensity. Expression intensity and heart rate were measured throughout the face-to-face/still-face (FFSF) in a sample of infants with prenatal cocaine exposure who were at risk for developmental difficulties. Smiles declined and cry-faces increased in the still-face episode, but the distribution of eye constriction and mouth opening in smiles and cry-faces did not differ across episodes of the FFSF. As time elapsed in the still face episode potential indices of intensity increased, cry-faces were more likely to be accompanied by eye constriction and mouth opening. During cry-faces there were also moderately stable individual differences in the quantity of eye constriction and mouth opening. Infant heart rate was higher during cry-faces and lower during smiles, but did not vary with intensity of expression or by episode. In sum, infants express more intense negative affect as the still-face progresses, but do not show clear differences in expressive intensity between episodes of the FFSF. Copyright © 2013 Elsevier Inc. All rights reserved.

Face-n-Food: Gender Differences in Tuning to Faces.

PubMed

Pavlova, Marina A; Scheffler, Klaus; Sokolov, Alexander N

2015-01-01

Faces represent valuable signals for social cognition and non-verbal communication. A wealth of research indicates that women tend to excel in recognition of facial expressions. However, it remains unclear whether females are better tuned to faces. We presented healthy adult females and males with a set of newly created food-plate images resembling faces (slightly bordering on the Giuseppe Arcimboldo style). In a spontaneous recognition task, participants were shown a set of images in a predetermined order from the least to most resembling a face. Females not only more readily recognized the images as a face (they reported resembling a face on images, on which males still did not), but gave on overall more face responses. The findings are discussed in the light of gender differences in deficient face perception. As most neuropsychiatric, neurodevelopmental and psychosomatic disorders characterized by social brain abnormalities are sex specific, the task may serve as a valuable tool for uncovering impairments in visual face processing.

Face-n-Food: Gender Differences in Tuning to Faces

PubMed Central

Pavlova, Marina A.; Scheffler, Klaus; Sokolov, Alexander N.

2015-01-01

Faces represent valuable signals for social cognition and non-verbal communication. A wealth of research indicates that women tend to excel in recognition of facial expressions. However, it remains unclear whether females are better tuned to faces. We presented healthy adult females and males with a set of newly created food-plate images resembling faces (slightly bordering on the Giuseppe Arcimboldo style). In a spontaneous recognition task, participants were shown a set of images in a predetermined order from the least to most resembling a face. Females not only more readily recognized the images as a face (they reported resembling a face on images, on which males still did not), but gave on overall more face responses. The findings are discussed in the light of gender differences in deficient face perception. As most neuropsychiatric, neurodevelopmental and psychosomatic disorders characterized by social brain abnormalities are sex specific, the task may serve as a valuable tool for uncovering impairments in visual face processing. PMID:26154177

Numerical modelling of channel processes and analysis of possible channel improvement measures on the Lena River near city Yakutsk

NASA Astrophysics Data System (ADS)

Krylenko, Inna; Belikov, Vitaly; Zavadskii, Aleksander; Borisova, Natalya; Golovlyov, Pavel; Rumyantsev, Alexey

2017-04-01

City Yakutsk (administrative, culture and industrial center of the North East of Russia) situated on the left bank of large Russian river Lena last decades has faced with many problems, concerning intensive channel processes. Most dramatic among them are sediment accumulation near main water intake structure, supplying city Yakutsk by the drinking water, and deterioration in conditions of the navigation roots to the main city ports. Hydrodynamic modelling has been chosen as the main tool for analyses of the modern tendencies in channel processes and for the evaluation of possible channel improvement measures efficiency. STREAM_2D program complex (authors V. Belikov et al.), which is based on the numerical solution of two-dimensional Saint-Venant equations on a hybrid curvilinear quadrangular and rectangular mesh and take into account sediment transport, was used for the simulations. Detailed field data about water regime of the Lena river, bathymetry of the channels and topography of the floodplains was collected for model developing. Model area has covered 75 km of the Lena river valley including branched channels and wide floodplain from Tabaga to Kangalassy gauge cites. Data of these stations were used for model boundary conditions assigning. Data of gauge station city Yakutsk as well as measured during field campaign water levels and flow velocities was taken into account for model calibration and validation. Results of modelling has demonstrated close correspondence with observed water levels and discharges distribution between channel branches for different hydrological situations. Different combinations of hydrographs of 1, 10, 50% exceedance probability was used as input for modelling of channel deformations. Simulation results has shown that in future 10 years aligning of water discharges distribution between main Lena river branches near Yakutsk is possible, that is a positive tendency from the point of view of water supply of the city. More than 15

The Breakdown: Hillslope Sources of Channel Blocks in Bedrock Landscapes

NASA Astrophysics Data System (ADS)

Selander, B.; Anderson, S. P.; Rossi, M.

2017-12-01

Block delivery from hillslopes is a poorly understood process that influences bedrock channel incision rates and shapes steep terrain. Previous studies demonstrate that hillslope sediment delivery rate and grain size increases with channel downcutting rate or fracture density (Attal et al., 2015, ESurf). However, blocks that exceed the competence of the channel can inhibit incision. In Boulder Creek, a bedrock channel in the Colorado Front Range, large boulders (>1 m diameter) are most numerous in the steepest channel reaches; their distribution seems to reflect autogenic channel-hillslope feedback between incision rate and block delivery (Shobe et al., 2016, GRL). It is clear that the processes, rates of production, and delivery of large blocks from hillslopes into channels are critical to our understanding of steep terrain evolution. Fundamental questions are 1) whether block production or block delivery is rate limiting, 2) what mechanisms release blocks, and 3) how block production and transport affect slope morphology. As a first step, we map rock outcrops on the granodiorite hillslopes lining Boulder Creek within Boulder Canyon using a high resolution DEM. Our algorithm uses high ranges of curvature values in conjunction with slopes steeper than the angle of repose to quickly identify rock outcrops. We field verified mapped outcrop and sediment-mantled locations on hillslopes above and below the channel knickzone. We find a greater abundance of exposed rock outcrops on steeper hillslopes in Boulder Canyon. Additionally, we find that channel reaches with large in-channel blocks are located at the base of hillslopes with large areas of exposed bedrock, while reaches lacking large in-channel blocks tend to be at the base of predominately soil mantled and forested hillslopes. These observations support the model of block delivery and channel incision of Shobe et al. (2016, GRL). Moreover, these results highlight the conundrum of how rapid channel incision is

Multi-stream face recognition on dedicated mobile devices for crime-fighting

NASA Astrophysics Data System (ADS)

Jassim, Sabah A.; Sellahewa, Harin

2006-09-01

Automatic face recognition is a useful tool in the fight against crime and terrorism. Technological advance in mobile communication systems and multi-application mobile devices enable the creation of hybrid platforms for active and passive surveillance. A dedicated mobile device that incorporates audio-visual sensors would not only complement existing networks of fixed surveillance devices (e.g. CCTV) but could also provide wide geographical coverage in almost any situation and anywhere. Such a device can hold a small portion of a law-enforcing agency biometric database that consist of audio and/or visual data of a number of suspects/wanted or missing persons who are expected to be in a local geographical area. This will assist law-enforcing officers on the ground in identifying persons whose biometric templates are downloaded onto their devices. Biometric data on the device can be regularly updated which will reduce the number of faces an officer has to remember. Such a dedicated device would act as an active/passive mobile surveillance unit that incorporate automatic identification. This paper is concerned with the feasibility of using wavelet-based face recognition schemes on such devices. The proposed schemes extend our recently developed face verification scheme for implementation on a currently available PDA. In particular we will investigate the use of a combination of wavelet frequency channels for multi-stream face recognition. We shall present experimental results on the performance of our proposed schemes for a number of publicly available face databases including a new AV database of videos recorded on a PDA.

Atomic Scale Dynamics of Contact Formation in the Cross-Section of InGaAs Nanowire Channels

DOE PAGES

Chen, Renjie; Jungjohann, Katherine L.; Mook, William M.; ...

2017-03-23

In the alloyed and compound contacts between metal and semiconductor transistor channels we see that they enable self-aligned gate processes which play a significant role in transistor scaling. At nanoscale dimensions and for nanowire channels, prior experiments focused on reactions along the channel length, but the early stage of reaction in their cross sections remains unknown. We report on the dynamics of the solid-state reaction between metal (Ni) and semiconductor (In 0.53Ga 0.47As), along the cross-section of nanowires that are 15 nm in width. Unlike planar structures where crystalline nickelide readily forms at conventional, low alloying temperatures, nanowires exhibit amore » solid-state amorphization step that can undergo a crystal regrowth step at elevated temperatures. Here, we capture the layer-by-layer reaction mechanism and growth rate anisotropy using in situ transmission electron microscopy (TEM). Our kinetic model depicts this new, in-plane contact formation which could pave the way for engineered nanoscale transistors.« less

Determination of optimal lot size and production rate for multi-production channels with limited capacity

NASA Astrophysics Data System (ADS)

Huang, Yeu-Shiang; Wang, Ruei-Pei; Ho, Jyh-Wen

2015-07-01

Due to the constantly changing business environment, producers often have to deal with customers by adopting different procurement policies. That is, manufacturers confront not only predictable and regular orders, but also unpredictable and irregular orders. In this study, from the perspective of upstream manufacturers, both regular and irregular orders are considered in coping with the situation in which an uncertain demand is faced by the manufacturer, and a capacity confirming mechanism is used to examine such demand. If the demand is less than or equal to the capacity of the ordinary production channel, the general supply channel is utilised to fully account for the manufacturing process, but if the demand is greater than the capacity of the ordinary production channel, the contingency production channel would be activated along with the ordinary channel to satisfy the upcoming high demand. Besides, the reproductive property of the probability distribution is employed to represent the order quantity of the two types of demand. Accordingly, the optimal production rates and lot sizes for both channels are derived to provide managers with insights for further production planning.

An Efficient ERP-Based Brain-Computer Interface Using Random Set Presentation and Face Familiarity

PubMed Central

Müller, Klaus-Robert; Lee, Seong-Whan

2014-01-01

Event-related potential (ERP)-based P300 spellers are commonly used in the field of brain-computer interfaces as an alternative channel of communication for people with severe neuro-muscular diseases. This study introduces a novel P300 based brain-computer interface (BCI) stimulus paradigm using a random set presentation pattern and exploiting the effects of face familiarity. The effect of face familiarity is widely studied in the cognitive neurosciences and has recently been addressed for the purpose of BCI. In this study we compare P300-based BCI performances of a conventional row-column (RC)-based paradigm with our approach that combines a random set presentation paradigm with (non-) self-face stimuli. Our experimental results indicate stronger deflections of the ERPs in response to face stimuli, which are further enhanced when using the self-face images, and thereby improving P300-based spelling performance. This lead to a significant reduction of stimulus sequences required for correct character classification. These findings demonstrate a promising new approach for improving the speed and thus fluency of BCI-enhanced communication with the widely used P300-based BCI setup. PMID:25384045

An efficient ERP-based brain-computer interface using random set presentation and face familiarity.

PubMed

Yeom, Seul-Ki; Fazli, Siamac; Müller, Klaus-Robert; Lee, Seong-Whan

2014-01-01

Event-related potential (ERP)-based P300 spellers are commonly used in the field of brain-computer interfaces as an alternative channel of communication for people with severe neuro-muscular diseases. This study introduces a novel P300 based brain-computer interface (BCI) stimulus paradigm using a random set presentation pattern and exploiting the effects of face familiarity. The effect of face familiarity is widely studied in the cognitive neurosciences and has recently been addressed for the purpose of BCI. In this study we compare P300-based BCI performances of a conventional row-column (RC)-based paradigm with our approach that combines a random set presentation paradigm with (non-) self-face stimuli. Our experimental results indicate stronger deflections of the ERPs in response to face stimuli, which are further enhanced when using the self-face images, and thereby improving P300-based spelling performance. This lead to a significant reduction of stimulus sequences required for correct character classification. These findings demonstrate a promising new approach for improving the speed and thus fluency of BCI-enhanced communication with the widely used P300-based BCI setup.

Free RCK arrangement in Kch, a putative escherichia coli potassium channel, as suggested by electron crystallography.

PubMed

Kuang, Qie; Purhonen, Pasi; Jegerschöld, Caroline; Koeck, Philip J B; Hebert, Hans

2015-01-06

The ligand-gated potassium channels are stimulated by various kinds of messengers. Previous studies showed that ligand-gated potassium channels containing RCK domains (the regulator of the conductance of potassium ion) form a dimer of tetramer structure through the RCK octameric gating ring in the presence of detergent. Here, we have analyzed the structure of Kch, a channel of this type from Escherichia coli, in a lipid environment using electron crystallography. By combining information from the 3D map of the transmembrane part of the protein and docking of an atomic model of a potassium channel, we conclude that the RCK domains face the solution and that an RCK octameric gating ring arrangement does not form under our crystallization condition. Our findings may be applied to other potassium channels that have an RCK gating ring arrangement. Copyright © 2015 Elsevier Ltd. All rights reserved.

The Caledonian face test: A new test of face discrimination.

PubMed

Logan, Andrew J; Wilkinson, Frances; Wilson, Hugh R; Gordon, Gael E; Loffler, Gunter

2016-02-01

This study aimed to develop a clinical test of face perception which is applicable to a wide range of patients and can capture normal variability. The Caledonian face test utilises synthetic faces which combine simplicity with sufficient realism to permit individual identification. Face discrimination thresholds (i.e. minimum difference between faces required for accurate discrimination) were determined in an "odd-one-out" task. The difference between faces was controlled by an adaptive QUEST procedure. A broad range of face discrimination sensitivity was determined from a group (N=52) of young adults (mean 5.75%; SD 1.18; range 3.33-8.84%). The test is fast (3-4 min), repeatable (test-re-test r(2)=0.795) and demonstrates a significant inversion effect. The potential to identify impairments of face discrimination was evaluated by testing LM who reported a lifelong difficulty with face perception. While LM's impairment for two established face tests was close to the criterion for significance (Z-scores of -2.20 and -2.27) for the Caledonian face test, her Z-score was -7.26, implying a more than threefold higher sensitivity. The new face test provides a quantifiable and repeatable assessment of face discrimination ability. The enhanced sensitivity suggests that the Caledonian face test may be capable of detecting more subtle impairments of face perception than available tests. Copyright © 2015 Elsevier Ltd. All rights reserved.

Face-Lift Satisfaction Using the FACE-Q.

PubMed

Sinno, Sammy; Schwitzer, Jonathan; Anzai, Lavinia; Thorne, Charles H

2015-08-01

Face lifting is one of the most common operative procedures for facial aging and perhaps the procedure most synonymous with plastic surgery in the minds of the lay public, but no verifiable documentation of patient satisfaction exists in the literature. This study is the first to examine face-lift outcomes and patient satisfaction using a validated questionnaire. One hundred five patients undergoing a face lift performed by the senior author (C.H.T.) using a high, extended-superficial musculoaponeurotic system with submental platysma approximation technique were asked to complete anonymously the FACE-Q by e-mail. FACE-Q scores were assessed for each domain (range, 0 to 100), with higher scores indicating greater satisfaction with appearance or superior quality of life. Fifty-three patients completed the FACE-Q (50.5 percent response rate). Patients demonstrated high satisfaction with facial appearance (mean ± SD, 80.7 ± 22.3), and quality of life, including social confidence (90.4 ± 16.6), psychological well-being (92.8 ± 14.3), and early life impact (92.2 ± 16.4). Patients also reported extremely high satisfaction with their decision to undergo face lifting (90.5 ± 15.9). On average, patients felt they appeared 6.9 years younger than their actual age. Patients were most satisfied with the appearance of their nasolabial folds (86.2 ± 18.5), cheeks (86.1 ± 25.4), and lower face/jawline (86.0 ± 20.6), compared with their necks (78.1 ± 25.6) and area under the chin (67.9 ± 32.3). Patients who responded in this study were extremely satisfied with their decision to undergo face lifting and the outcomes and quality of life following the procedure.

A Face Inversion Effect without a Face

ERIC Educational Resources Information Center

Brandman, Talia; Yovel, Galit

2012-01-01

Numerous studies have attributed the face inversion effect (FIE) to configural processing of internal facial features in upright but not inverted faces. Recent findings suggest that face mechanisms can be activated by faceless stimuli presented in the context of a body. Here we asked whether faceless stimuli with or without body context may induce…

Transmembrane helical interactions in the CFTR channel pore.

PubMed

Das, Jhuma; Aleksandrov, Andrei A; Cui, Liying; He, Lihua; Riordan, John R; Dokholyan, Nikolay V

2017-06-01

Mutations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene affect CFTR protein biogenesis or its function as a chloride channel, resulting in dysregulation of epithelial fluid transport in the lung, pancreas and other organs in cystic fibrosis (CF). Development of pharmaceutical strategies to treat CF requires understanding of the mechanisms underlying channel function. However, incomplete 3D structural information on the unique ABC ion channel, CFTR, hinders elucidation of its functional mechanism and correction of cystic fibrosis causing mutants. Several CFTR homology models have been developed using bacterial ABC transporters as templates but these have low sequence similarity to CFTR and are not ion channels. Here, we refine an earlier model in an outward (OWF) and develop an inward (IWF) facing model employing an integrated experimental-molecular dynamics simulation (200 ns) approach. Our IWF structure agrees well with a recently solved cryo-EM structure of a CFTR IWF state. We utilize cysteine cross-linking to verify positions and orientations of residues within trans-membrane helices (TMHs) of the OWF conformation and to reconstruct a physiologically relevant pore structure. Comparison of pore profiles of the two conformations reveal a radius sufficient to permit passage of hydrated Cl- ions in the OWF but not the IWF model. To identify structural determinants that distinguish the two conformations and possible rearrangements of TMHs within them responsible for channel gating, we perform cross-linking by bifunctional reagents of multiple predicted pairs of cysteines in TMH 6 and 12 and 6 and 9. To determine whether the effects of cross-linking on gating observed are the result of switching of the channel from open to close state, we also treat the same residue pairs with monofunctional reagents in separate experiments. Both types of reagents prevent ion currents indicating that pore blockage is primarily responsible.

Face to Face Communications in Space

NASA Technical Reports Server (NTRS)

Cohen, Malcolm M.; Davon, Bonnie P. (Technical Monitor)

1999-01-01

It has been reported that human face-to-face communications in space are compromised by facial edema, variations in the orientations of speakers and listeners, and background noises that are encountered in the shuttle and in space stations. To date, nearly all reports have been anecdotal or subjective, in the form of post-flight interviews or questionnaires; objective and quantitative data are generally lacking. Although it is acknowledged that efficient face-to-face communications are essential for astronauts to work safely and effectively, specific ways in which the space environment interferes with non-linguistic communication cues are poorly documented. Because we have only a partial understanding of how non-linguistic communication cues may change with mission duration, it is critically important to obtain objective data, and to evaluate these cues under well-controlled experimental conditions.

Further insight into self-face recognition in schizophrenia patients: Why ambiguity matters.

PubMed

Bortolon, Catherine; Capdevielle, Delphine; Salesse, Robin N; Raffard, Stephane

2016-03-01

Although some studies reported specifically self-face processing deficits in patients with schizophrenia disorder (SZ), it remains unclear whether these deficits rather reflect a more global face processing deficit. Contradictory results are probably due to the different methodologies employed and the lack of control of other confounding factors. Moreover, no study has so far evaluated possible daily life self-face recognition difficulties in SZ. Therefore, our primary objective was to investigate self-face recognition in patients suffering from SZ compared to healthy controls (HC) using an "objective measure" (reaction time and accuracy) and a "subjective measure" (self-report of daily self-face recognition difficulties). Twenty-four patients with SZ and 23 HC performed a self-face recognition task and completed a questionnaire evaluating daily difficulties in self-face recognition. Recognition task material consisted in three different faces (the own, a famous and an unknown) being morphed in steps of 20%. Results showed that SZ were overall slower than HC regardless of the face identity, but less accurate only for the faces containing 60%-40% morphing. Moreover, SZ and HC reported a similar amount of daily problems with self/other face recognition. No significant correlations were found between objective and subjective measures (p > 0.05). The small sample size and relatively mild severity of psychopathology does not allow us to generalize our results. These results suggest that: (1) patients with SZ are as capable of recognizing their own face as HC, although they are susceptible to ambiguity; (2) there are far less self recognition deficits in schizophrenia patients than previously postulated. Copyright © 2015 Elsevier Ltd. All rights reserved.

Illumination normalization of face image based on illuminant direction estimation and improved Retinex.

PubMed

Yi, Jizheng; Mao, Xia; Chen, Lijiang; Xue, Yuli; Rovetta, Alberto; Caleanu, Catalin-Daniel

2015-01-01

Illumination normalization of face image for face recognition and facial expression recognition is one of the most frequent and difficult problems in image processing. In order to obtain a face image with normal illumination, our method firstly divides the input face image into sixteen local regions and calculates the edge level percentage in each of them. Secondly, three local regions, which meet the requirements of lower complexity and larger average gray value, are selected to calculate the final illuminant direction according to the error function between the measured intensity and the calculated intensity, and the constraint function for an infinite light source model. After knowing the final illuminant direction of the input face image, the Retinex algorithm is improved from two aspects: (1) we optimize the surround function; (2) we intercept the values in both ends of histogram of face image, determine the range of gray levels, and stretch the range of gray levels into the dynamic range of display device. Finally, we achieve illumination normalization and get the final face image. Unlike previous illumination normalization approaches, the method proposed in this paper does not require any training step or any knowledge of 3D face and reflective surface model. The experimental results using extended Yale face database B and CMU-PIE show that our method achieves better normalization effect comparing with the existing techniques.

Healing the healer: one step at a time.

PubMed

Gershon, J Casey

2014-03-01

Health care workers have the most challenging of professions. They are expected to work long hours while demonstrating compassion and care for the patients that they serve. Although health care practitioners are among the most disciplined of working professionals, they are often some of the unhealthiest of individuals, facing enormous amounts of stress in their lives. Healing the Healer: One Step at a Time is a 6-week health fitness program. It explores the unique challenges faced in the field of health care and teaches techniques to address those challenges head on. Healing the Healer uses Nordic walking as the exercise portion of the class. The case study examines the structure, purpose, and design of this 6-week course. Special attention is given to four basic sections: balance, pacing, joy, and discipline. The arguments presented in this article are theory based and supported by case study evidence.

Coffee-Ring Defined Short Channels for Inkjet-Printed Metal Oxide Thin-Film Transistors.

PubMed

Li, Yuzhi; Lan, Linfeng; Xiao, Peng; Sun, Sheng; Lin, Zhenguo; Song, Wei; Song, Erlong; Gao, Peixiong; Wu, Weijing; Peng, Junbiao

2016-08-03

Short-channel electronic devices several micrometers in length are difficult to implement by direct inkjet printing due to the limitation of position accuracy of the common inkjet printer system and the spread of functional ink on substrates. In this report, metal oxide thin-film transistors (TFTs) with channel lengths of 3.5 ± 0.7 μm were successfully fabricated with a common inkjet printer without any photolithography steps. Hydrophobic CYTOP coffee stripes, made by inkjet-printing and plasma-treating processes, were utilized to define the channel area of TFTs with channel lengths as short as ∼3.5 μm by dewetting the inks of the source/drain (S/D) precursors. Furthermore, by introduction of an ultrathin layer of PVA to modify the S/D surfaces, the spreading of precursor ink of the InOx semiconductor layer was well-controlled. The inkjet-printed short-channel TFTs exhibited a maximum mobility of 4.9 cm(2) V(-1) s(-1) and an on/off ratio of larger than 10(9). This approach of fabricating short-channel TFTs by inkjet printing will promote the large-area fabrication of short-channel TFTs in a cost-effective manner.

pH-Controlled Two-Step Uncoating of Influenza Virus

PubMed Central

Li, Sai; Sieben, Christian; Ludwig, Kai; Höfer, Chris T.; Chiantia, Salvatore; Herrmann, Andreas; Eghiaian, Frederic; Schaap, Iwan A.T.

2014-01-01

Upon endocytosis in its cellular host, influenza A virus transits via early to late endosomes. To efficiently release its genome, the composite viral shell must undergo significant structural rearrangement, but the exact sequence of events leading to viral uncoating remains largely speculative. In addition, no change in viral structure has ever been identified at the level of early endosomes, raising a question about their role. We performed AFM indentation on single viruses in conjunction with cellular assays under conditions that mimicked gradual acidification from early to late endosomes. We found that the release of the influenza genome requires sequential exposure to the pH of both early and late endosomes, with each step corresponding to changes in the virus mechanical response. Step 1 (pH 7.5–6) involves a modification of both hemagglutinin and the viral lumen and is reversible, whereas Step 2 (pH <6.0) involves M1 dissociation and major hemagglutinin conformational changes and is irreversible. Bypassing the early-endosomal pH step or blocking the envelope proton channel M2 precludes proper genome release and efficient infection, illustrating the importance of viral lumen acidification during the early endosomal residence for influenza virus infection. PMID:24703306

pH-Controlled two-step uncoating of influenza virus.

PubMed

Li, Sai; Sieben, Christian; Ludwig, Kai; Höfer, Chris T; Chiantia, Salvatore; Herrmann, Andreas; Eghiaian, Frederic; Schaap, Iwan A T

2014-04-01

Upon endocytosis in its cellular host, influenza A virus transits via early to late endosomes. To efficiently release its genome, the composite viral shell must undergo significant structural rearrangement, but the exact sequence of events leading to viral uncoating remains largely speculative. In addition, no change in viral structure has ever been identified at the level of early endosomes, raising a question about their role. We performed AFM indentation on single viruses in conjunction with cellular assays under conditions that mimicked gradual acidification from early to late endosomes. We found that the release of the influenza genome requires sequential exposure to the pH of both early and late endosomes, with each step corresponding to changes in the virus mechanical response. Step 1 (pH 7.5-6) involves a modification of both hemagglutinin and the viral lumen and is reversible, whereas Step 2 (pH <6.0) involves M1 dissociation and major hemagglutinin conformational changes and is irreversible. Bypassing the early-endosomal pH step or blocking the envelope proton channel M2 precludes proper genome release and efficient infection, illustrating the importance of viral lumen acidification during the early endosomal residence for influenza virus infection. Copyright © 2014 Biophysical Society. Published by Elsevier Inc. All rights reserved.

Comparison of detectability in step-and-shoot mode and continuous mode digital tomosynthesis systems

NASA Astrophysics Data System (ADS)

Lee, Changwoo; Han, Minah; Baek, Jongduk

2017-03-01

Digital tomosynthesis system has been widely used in chest, dental, and breast imaging. Since the digital tomosynthesis system provides volumetric images from multiple projection data, structural noise inherent in X-ray radiograph can be reduced, and thus signal detection performance is improved. Currently, tomosynthesis system uses two data acquisition modes: step-and-shoot mode and continuous mode. Several studies have been conducted to compare the system performance of two acquisition modes with respect to spatial resolution and contrast. In this work, we focus on signal detectability in step-and-shoot mode and continuous mode. For evaluation, uniform background is considered, and eight spherical objects with diameters of 0.5, 0.8, 1, 2, 3, 5, 8, 10 mm are used as signals. Projection data with and without spherical objects are acquired in step-and-shoot mode and continuous mode, respectively, and quantum noise are added. Then, noisy projection data are reconstructed by FDK algorithm. To compare the detection performance of two acquisition modes, we calculate task signal-to-noise ratio (SNR) of channelized Hotelling observer with Laguerre-Gauss channels for each spherical object. While the task-SNR values of two acquisition modes are similar for spherical objects larger than 1 mm diameter, step-and-shoot mode yields higher detectability for small signal sizes. The main reason of this behavior is that small signal is more affected by X-ray tube motion blur than large signal. Our results indicate that it is beneficial to use step-and-shoot data acquisition mode to improve the detectability of small signals (i.e., less than 1 mm diameter) in digital tomosynthesis systems.

Modeling-independent elucidation of inactivation pathways in recombinant and native A-type Kv channels.

PubMed

Fineberg, Jeffrey D; Ritter, David M; Covarrubias, Manuel

2012-11-01

A-type voltage-gated K(+) (Kv) channels self-regulate their activity by inactivating directly from the open state (open-state inactivation [OSI]) or by inactivating before they open (closed-state inactivation [CSI]). To determine the inactivation pathways, it is often necessary to apply several pulse protocols, pore blockers, single-channel recording, and kinetic modeling. However, intrinsic hurdles may preclude the standardized application of these methods. Here, we implemented a simple method inspired by earlier studies of Na(+) channels to analyze macroscopic inactivation and conclusively deduce the pathways of inactivation of recombinant and native A-type Kv channels. We investigated two distinct A-type Kv channels expressed heterologously (Kv3.4 and Kv4.2 with accessory subunits) and their native counterparts in dorsal root ganglion and cerebellar granule neurons. This approach applies two conventional pulse protocols to examine inactivation induced by (a) a simple step (single-pulse inactivation) and (b) a conditioning step (double-pulse inactivation). Consistent with OSI, the rate of Kv3.4 inactivation (i.e., the negative first derivative of double-pulse inactivation) precisely superimposes on the profile of the Kv3.4 current evoked by a single pulse because the channels must open to inactivate. In contrast, the rate of Kv4.2 inactivation is asynchronous, already changing at earlier times relative to the profile of the Kv4.2 current evoked by a single pulse. Thus, Kv4.2 inactivation occurs uncoupled from channel opening, indicating CSI. Furthermore, the inactivation time constant versus voltage relation of Kv3.4 decreases monotonically with depolarization and levels off, whereas that of Kv4.2 exhibits a J-shape profile. We also manipulated the inactivation phenotype by changing the subunit composition and show how CSI and CSI combined with OSI might affect spiking properties in a full computational model of the hippocampal CA1 neuron. This work unambiguously

Modeling-independent elucidation of inactivation pathways in recombinant and native A-type Kv channels

PubMed Central

Fineberg, Jeffrey D.; Ritter, David M.

2012-01-01

A-type voltage-gated K+ (Kv) channels self-regulate their activity by inactivating directly from the open state (open-state inactivation [OSI]) or by inactivating before they open (closed-state inactivation [CSI]). To determine the inactivation pathways, it is often necessary to apply several pulse protocols, pore blockers, single-channel recording, and kinetic modeling. However, intrinsic hurdles may preclude the standardized application of these methods. Here, we implemented a simple method inspired by earlier studies of Na+ channels to analyze macroscopic inactivation and conclusively deduce the pathways of inactivation of recombinant and native A-type Kv channels. We investigated two distinct A-type Kv channels expressed heterologously (Kv3.4 and Kv4.2 with accessory subunits) and their native counterparts in dorsal root ganglion and cerebellar granule neurons. This approach applies two conventional pulse protocols to examine inactivation induced by (a) a simple step (single-pulse inactivation) and (b) a conditioning step (double-pulse inactivation). Consistent with OSI, the rate of Kv3.4 inactivation (i.e., the negative first derivative of double-pulse inactivation) precisely superimposes on the profile of the Kv3.4 current evoked by a single pulse because the channels must open to inactivate. In contrast, the rate of Kv4.2 inactivation is asynchronous, already changing at earlier times relative to the profile of the Kv4.2 current evoked by a single pulse. Thus, Kv4.2 inactivation occurs uncoupled from channel opening, indicating CSI. Furthermore, the inactivation time constant versus voltage relation of Kv3.4 decreases monotonically with depolarization and levels off, whereas that of Kv4.2 exhibits a J-shape profile. We also manipulated the inactivation phenotype by changing the subunit composition and show how CSI and CSI combined with OSI might affect spiking properties in a full computational model of the hippocampal CA1 neuron. This work unambiguously

A novel thermal face recognition approach using face pattern words

NASA Astrophysics Data System (ADS)

Zheng, Yufeng

2010-04-01

A reliable thermal face recognition system can enhance the national security applications such as prevention against terrorism, surveillance, monitoring and tracking, especially at nighttime. The system can be applied at airports, customs or high-alert facilities (e.g., nuclear power plant) for 24 hours a day. In this paper, we propose a novel face recognition approach utilizing thermal (long wave infrared) face images that can automatically identify a subject at both daytime and nighttime. With a properly acquired thermal image (as a query image) in monitoring zone, the following processes will be employed: normalization and denoising, face detection, face alignment, face masking, Gabor wavelet transform, face pattern words (FPWs) creation, face identification by similarity measure (Hamming distance). If eyeglasses are present on a subject's face, an eyeglasses mask will be automatically extracted from the querying face image, and then masked with all comparing FPWs (no more transforms). A high identification rate (97.44% with Top-1 match) has been achieved upon our preliminary face dataset (of 39 subjects) from the proposed approach regardless operating time and glasses-wearing condition.e

Acid stress mediated adaptive divergence in ion channel function during embryogenesis in Rana arvalis

PubMed Central

Shu, Longfei; Laurila, Anssi; Räsänen, Katja

2015-01-01

Ion channels and pumps are responsible for ion flux in cells, and are key mechanisms mediating cellular function. Many environmental stressors, such as salinity and acidification, are known to severely disrupt ionic balance of organisms thereby challenging fitness of natural populations. Although ion channels can have several vital functions during early life-stages (e.g. embryogenesis), it is currently not known i) how developing embryos maintain proper intracellular conditions when exposed to environmental stress and ii) to what extent environmental stress can drive intra-specific divergence in ion channels. Here we studied the moor frog, Rana arvalis, from three divergent populations to investigate the role of different ion channels and pumps for embryonic survival under acid stress (pH 4 vs 7.5) and whether populations adapted to contrasting acidities differ in the relative role of different ion channel/pumps. We found that ion channels that mediate Ca2+ influx are essential for embryonic survival under acidic pH, and, intriguingly, that populations differ in calcium channel function. Our results suggest that adaptive divergence in embryonic acid stress tolerance of amphibians may in part be mediated by Ca2+ balance. We suggest that ion flux may mediate adaptive divergence of natural populations at early life-stages in the face of environmental stress. PMID:26381453

Face time: educating face transplant candidates.

PubMed

Lamparello, Brooke M; Bueno, Ericka M; Diaz-Siso, Jesus Rodrigo; Sisk, Geoffroy C; Pomahac, Bohdan

2013-01-01

Face transplantation is the innovative application of microsurgery and immunology to restore appearance and function to those with severe facial disfigurements. Our group aims to establish a multidisciplinary education program that can facilitate informed consent and build a strong knowledge base in patients to enhance adherence to medication regimes, recovery, and quality of life. We analyzed handbooks from our institution's solid organ transplant programs to identify topics applicable to face transplant patients. The team identified unique features of face transplantation that warrant comprehensive patient education. We created a 181-page handbook to provide subjects interested in pursuing transplantation with a written source of information on the process and team members and to address concerns they may have. While the handbook covers a wide range of topics, it is easy to understand and visually appealing. Face transplantation has many unique aspects that must be relayed to the patients pursuing this novel therapy. Since candidates lack third-party support groups and programs, the transplant team must provide an extensive educational component to enhance this complex process. As face transplantation continues to develop, programs must create sound education programs that address patients' needs and concerns to facilitate optimal care.

Exploration of the pore structure of a peptide-gated Na+channel

PubMed Central

Poët, Mallorie; Tauc, Michel; Lingueglia, Eric; Cance, Peggy; Poujeol, Philippe; Lazdunski, Michel; Counillon, Laurent

2001-01-01

The FMRF-amide-activated sodium channel (FaNaC), a member of the ENaC/Degenerin family, is a homotetramer, each subunit containing two transmembrane segments. We changed independently every residue of the first transmembrane segment (TM1) into a cysteine and tested each position’s accessibility to the cysteine covalent reagents MTSET and MTSES. Eleven mutants were accessible to the cationic MTSET, showing that TM1 faces the ion translocation pathway. This was confirmed by the accessibility of cysteines present in the acid-sensing ion channels and other mutations introduced in FaNaC TM1. Modification of accessibilities for positions 69, 71 and 72 in the open state shows that the gating mechanism consists of the opening of a constriction close to the intracellular side. The anionic MTSES did not penetrate into the channel, indicating the presence of a charge selectivity filter in the outer vestibule. Furthermore, amiloride inhibition resulted in the channel occlusion in the middle of the pore. Summarizing, the ionic pore of FaNaC includes a large aqueous cavity, with a charge selectivity filter in the outer vestibule and the gate close to the interior. PMID:11598003

From face processing to face recognition: Comparing three different processing levels.

PubMed

Besson, G; Barragan-Jason, G; Thorpe, S J; Fabre-Thorpe, M; Puma, S; Ceccaldi, M; Barbeau, E J

2017-01-01

Verifying that a face is from a target person (e.g. finding someone in the crowd) is a critical ability of the human face processing system. Yet how fast this can be performed is unknown. The 'entry-level shift due to expertise' hypothesis suggests that - since humans are face experts - processing faces should be as fast - or even faster - at the individual than at superordinate levels. In contrast, the 'superordinate advantage' hypothesis suggests that faces are processed from coarse to fine, so that the opposite pattern should be observed. To clarify this debate, three different face processing levels were compared: (1) a superordinate face categorization level (i.e. detecting human faces among animal faces), (2) a face familiarity level (i.e. recognizing famous faces among unfamiliar ones) and (3) verifying that a face is from a target person, our condition of interest. The minimal speed at which faces can be categorized (∼260ms) or recognized as familiar (∼360ms) has largely been documented in previous studies, and thus provides boundaries to compare our condition of interest to. Twenty-seven participants were included. The recent Speed and Accuracy Boosting procedure paradigm (SAB) was used since it constrains participants to use their fastest strategy. Stimuli were presented either upright or inverted. Results revealed that verifying that a face is from a target person (minimal RT at ∼260ms) was remarkably fast but longer than the face categorization level (∼240ms) and was more sensitive to face inversion. In contrast, it was much faster than recognizing a face as familiar (∼380ms), a level severely affected by face inversion. Face recognition corresponding to finding a specific person in a crowd thus appears achievable in only a quarter of a second. In favor of the 'superordinate advantage' hypothesis or coarse-to-fine account of the face visual hierarchy, these results suggest a graded engagement of the face processing system across processing

Conjunction Faces Alter Confidence-Accuracy Relations for Old Faces

ERIC Educational Resources Information Center

Reinitz, Mark Tippens; Loftus, Geoffrey R.

2017-01-01

The authors used a state-trace methodology to investigate the informational dimensions used to recognize old and conjunction faces (made by combining parts of separately studied faces). Participants in 3 experiments saw faces presented for 1 s each. They then received a recognition test; faces were presented for varying brief durations and…

Bayesian Face Recognition and Perceptual Narrowing in Face-Space

ERIC Educational Resources Information Center

Balas, Benjamin

2012-01-01

During the first year of life, infants' face recognition abilities are subject to "perceptual narrowing", the end result of which is that observers lose the ability to distinguish previously discriminable faces (e.g. other-race faces) from one another. Perceptual narrowing has been reported for faces of different species and different races, in…

Holistic face training enhances face processing in developmental prosopagnosia

PubMed Central

Cohan, Sarah; Nakayama, Ken

2014-01-01

Prosopagnosia has largely been regarded as an untreatable disorder. However, recent case studies using cognitive training have shown that it is possible to enhance face recognition abilities in individuals with developmental prosopagnosia. Our goal was to determine if this approach could be effective in a larger population of developmental prosopagnosics. We trained 24 developmental prosopagnosics using a 3-week online face-training program targeting holistic face processing. Twelve subjects with developmental prosopagnosia were assessed before and after training, and the other 12 were assessed before and after a waiting period, they then performed the training, and were then assessed again. The assessments included measures of front-view face discrimination, face discrimination with view-point changes, measures of holistic face processing, and a 5-day diary to quantify potential real-world improvements. Compared with the waiting period, developmental prosopagnosics showed moderate but significant overall training-related improvements on measures of front-view face discrimination. Those who reached the more difficult levels of training (‘better’ trainees) showed the strongest improvements in front-view face discrimination and showed significantly increased holistic face processing to the point of being similar to that of unimpaired control subjects. Despite challenges in characterizing developmental prosopagnosics’ everyday face recognition and potential biases in self-report, results also showed modest but consistent self-reported diary improvements. In summary, we demonstrate that by using cognitive training that targets holistic processing, it is possible to enhance face perception across a group of developmental prosopagnosics and further suggest that those who improved the most on the training task received the greatest benefits. PMID:24691394

Dissimilar viscosity induced sample pre-concentration in elecrokinetic nanofluidic channels

NASA Astrophysics Data System (ADS)

Wink, Dean; Shelton, Elijah; Pennathur, Sumita; Storey, Brian

2013-11-01

Nanofluidic analysis systems boast many advantages: portability, small sample handling, short processing times, and potential for integration with mobile electronics. However, such systems face the challenge of detecting increasingly small volumes of sample at low concentrations. In this work, we demonstrate a unique pre-concentration technique in electrokinetic nanofluidic systems based on a viscosity mismatch between two fluids. In nanofluidic electrokinetic systems, finite electric double layers (EDL) lead to non-uniform electric potentials and transverse concentration distributions. Therefore, when the EDL is comparable in size to the channel height, negatively charged ions are repelled from negatively charged walls and preferentially populate the channel centerline. Furthermore, an axial piecewise viscosity distribution induces internal pressure gradients within the channel. These force the ions to move at a different average velocities based on the pressure gradient being favorable or adverse, leading to focusing. To experimentally probe this phenomenon, we electrokinetically inject solutions of borate buffer with and without glycerol (to change the viscosity) and use a fluorescent tracer dye to visualize the flow. We perform the injections in cross-geometry channels of 20 micron, 1 micron, and 250 nanometer depths. We measure fluorescence at 5, 10 and 15 mm distances from junction. Enhancement is characterized by comparing intensities to control measurements for systems with uniform viscosity.

Study on statistical models for land mobile satellite channel

NASA Astrophysics Data System (ADS)

Wang, Ying; Hu, Xiulin

2005-11-01

Mobile terminals in a mobile satellite communication system cause the radio propagation channel to vary with time. So it is necessary to study the channel models in order to estimate the behavior of satellite signal propagation. A lot of research work have been done on the L- and S- bands. With the development of gigabit data transmissions and multimedia applications in recent years, the Ka-band studies gain much attention. Non-geostationary satellites are also in research because of its low propagation delay and low path loss. The future satellite mobile communication systems would be integrated into the other terrestrial networks in order to enable global, seamless and ubiquitous communications. At the same time QoS-technologies are studied to satisfy users' different service classes, such as mobility and resource managements. All the above make a suitable efficient channel model face new challenges. This paper firstly introduces existed channel models and analyzes their respective characteristics. Then we focus on a general model presented by Xie YongJun, which is popular under any environment and describes difference through different parameter values. However we believe that it is better to take multi-state Markov model as category in order to adapt to different environments. So a general model based on Markov process is presented and necessary simulation is carried out.

The complex duration perception of emotional faces: effects of face direction.

PubMed

Kliegl, Katrin M; Limbrecht-Ecklundt, Kerstin; Dürr, Lea; Traue, Harald C; Huckauf, Anke

2015-01-01

The perceived duration of emotional face stimuli strongly depends on the expressed emotion. But, emotional faces also differ regarding a number of other features like gaze, face direction, or sex. Usually, these features have been controlled by only using pictures of female models with straight gaze and face direction. Doi and Shinohara (2009) reported that an overestimation of angry faces could only be found when the model's gaze was oriented toward the observer. We aimed at replicating this effect for face direction. Moreover, we explored the effect of face direction on the duration perception sad faces. Controlling for the sex of the face model and the participant, female and male participants rated the duration of neutral, angry, and sad face stimuli of both sexes photographed from different perspectives in a bisection task. In line with current findings, we report a significant overestimation of angry compared to neutral face stimuli that was modulated by face direction. Moreover, the perceived duration of sad face stimuli did not differ from that of neutral faces and was not influenced by face direction. Furthermore, we found that faces of the opposite sex appeared to last longer than those of the same sex. This outcome is discussed with regards to stimulus parameters like the induced arousal, social relevance, and an evolutionary context.

One-microsecond molecular dynamics simulation of channel gating in a nicotinic receptor homologue

PubMed Central

Nury, Hugues; Poitevin, Frédéric; Van Renterghem, Catherine; Changeux, Jean-Pierre; Corringer, Pierre-Jean; Delarue, Marc; Baaden, Marc

2010-01-01

Recently discovered bacterial homologues of eukaryotic pentameric ligand-gated ion channels, such as the Gloeobacter violaceus receptor (GLIC), are increasingly used as structural and functional models of signal transduction in the nervous system. Here we present a one-microsecond-long molecular dynamics simulation of the GLIC channel pH stimulated gating mechanism. The crystal structure of GLIC obtained at acidic pH in an open-channel form is equilibrated in a membrane environment and then instantly set to neutral pH. The simulation shows a channel closure that rapidly takes place at the level of the hydrophobic furrow and a progressively increasing quaternary twist. Two major events are captured during the simulation. They are initiated by local but large fluctuations in the pore, taking place at the top of the M2 helix, followed by a global tertiary relaxation. The two-step transition of the first subunit starts within the first 50 ns of the simulation and is followed at 450 ns by its immediate neighbor in the pentamer, which proceeds with a similar scenario. This observation suggests a possible two-step domino-like tertiary mechanism that takes place between adjacent subunits. In addition, the dynamical properties of GLIC described here offer an interpretation of the paradoxical properties of a permeable A13′F mutant whose crystal structure determined at 3.15 Å shows a pore too narrow to conduct ions. PMID:20308576

Substance P Depolarizes Lamprey Spinal Cord Neurons by Inhibiting Background Potassium Channels.

PubMed

Thörn Pérez, Carolina; Hill, Russell H; Grillner, Sten

2015-01-01

Substance P is endogenously released in the adult lamprey spinal cord and accelerates the burst frequency of fictive locomotion. This is achieved by multiple effects on interneurons and motoneurons, including an attenuation of calcium currents, potentiation of NMDA currents and reduction of the reciprocal inhibition. While substance P also depolarizes spinal cord neurons, the underlying mechanism has not been resolved. Here we show that effects of substance P on background K+ channels are the main source for this depolarization. Hyperpolarizing steps induced inward currents during whole-cell voltage clamp that were reduced by substance P. These background K+ channels are pH sensitive and are selectively blocked by anandamide and AVE1231. These blockers counteracted the effect of substance P on these channels and the resting membrane potential depolarization in spinal cord neurons. Thus, we have shown now that substance P inhibits background K+ channels that in turn induce depolarization, which is likely to contribute to the frequency increase observed with substance P during fictive locomotion.

Face Time: Educating Face Transplant Candidates

PubMed Central

Lamparello, Brooke M.; Bueno, Ericka M.; Diaz-Siso, Jesus Rodrigo; Sisk, Geoffroy C.; Pomahac, Bohdan

2013-01-01

Objective: Face transplantation is the innovative application of microsurgery and immunology to restore appearance and function to those with severe facial disfigurements. Our group aims to establish a multidisciplinary education program that can facilitate informed consent and build a strong knowledge base in patients to enhance adherence to medication regimes, recovery, and quality of life. Methods: We analyzed handbooks from our institution's solid organ transplant programs to identify topics applicable to face transplant patients. The team identified unique features of face transplantation that warrant comprehensive patient education. Results: We created a 181-page handbook to provide subjects interested in pursuing transplantation with a written source of information on the process and team members and to address concerns they may have. While the handbook covers a wide range of topics, it is easy to understand and visually appealing. Conclusions: Face transplantation has many unique aspects that must be relayed to the patients pursuing this novel therapy. Since candidates lack third-party support groups and programs, the transplant team must provide an extensive educational component to enhance this complex process. Practice Implications: As face transplantation continues to develop, programs must create sound education programs that address patients’ needs and concerns to facilitate optimal care. PMID:23861990

n-Alkanols potentiate sodium channel inactivation in squid giant axons.

PubMed Central

Oxford, G S; Swenson, R P

1979-01-01

The effects of n-octanol and n-decanol on nerve membrane sodium channels were examined in internally perfused, voltage-clamped squid giant axons. Both n-octanol and n-decanol almost completely eliminated the residual sodium conductance at the end of 8-ms voltage steps. In contrast, peak sodium conductance was only partially reduced. This block of peak and residual sodium conductance was very reversible and seen with both internal and external alkanol application. The differential sensitivity of peak and residual conductance to alkanol treatment was eliminated after internal pronase treatment, suggesting that n-octanol and n-decanol enhance the normal inactivation mechanism rather than directly blocking channels in a time-dependent manner. PMID:233577

Withholding response to self-face is faster than to other-face.

PubMed

Zhu, Min; Hu, Yinying; Tang, Xiaochen; Luo, Junlong; Gao, Xiangping

2015-01-01

Self-face advantage refers to adults' response to self-face is faster than that to other-face. A stop-signal task was used to explore how self-face advantage interacted with response inhibition. The results showed that reaction times of self-face were faster than that of other-face not in the go task but in the stop response trials. The novelty of the finding was that self-face has shorter stop-signal reaction time compared to other-face in the successful inhibition trials. These results indicated the processing mechanism of self-face may be characterized by a strong response tendency and a corresponding strong inhibition control.

Filament Channel Formation, Eruption, and Jet Generation

NASA Astrophysics Data System (ADS)

DeVore, C. Richard; Antiochos, Spiro K.; Karpen, Judith T.

2017-08-01

The mechanism behind filament-channel formation is a longstanding mystery, while that underlying the initiation of coronal mass ejections and jets has been studied intensively but is not yet firmly established. In previous work, we and collaborators have investigated separately the consequences of magnetic-helicity condensation (Antiochos 2013) for forming filament channels (Zhao et al. 2015; Knizhnik et al. 2015, 2017a,b) and of the embedded-bipole model (Antiochos 1996) for generating reconnection-driven jets (Pariat et al. 2009, 2010, 2015, 2016; Wyper et al. 2016, 2017). Now we have taken a first step toward synthesizing these two lines of investigation. Our recent study (Karpen et al. 2017) of coronal-hole jets with gravity and wind employed an ad hoc, large-scale shear flow at the surface to introduce magnetic free energy and form the filament channel. In this effort, we replace the shear flow with an ensemble of local rotation cells, to emulate the Sun’s ever-changing granules and supergranules. As in our previous studies, we find that reconnection between twisted flux tubes within the closed-field region concentrates magnetic shear and free energy near the polarity inversion line, forming the filament channel. Onset of reconnection between this field and the external, unsheared, open field releases stored energy to drive the impulsive jet. We discuss the results of our new simulations with implications for understanding solar activity and space weather.

A MULTIPLE GRID APPROACH FOR OPEN CHANNEL FLOWS WITH STRONG SHOCKS. (R825200)

EPA Science Inventory

Abstract

Explicit finite difference schemes are being widely used for modeling open channel flows accompanied with shocks. A characteristic feature of explicit schemes is the small time step, which is limited by the CFL stability condition. To overcome this limitation,...

A Low-Noise Transimpedance Amplifier for BLM-Based Ion Channel Recording.

PubMed

Crescentini, Marco; Bennati, Marco; Saha, Shimul Chandra; Ivica, Josip; de Planque, Maurits; Morgan, Hywel; Tartagni, Marco

2016-05-19

High-throughput screening (HTS) using ion channel recording is a powerful drug discovery technique in pharmacology. Ion channel recording with planar bilayer lipid membranes (BLM) is scalable and has very high sensitivity. A HTS system based on BLM ion channel recording faces three main challenges: (i) design of scalable microfluidic devices; (ii) design of compact ultra-low-noise transimpedance amplifiers able to detect currents in the pA range with bandwidth >10 kHz; (iii) design of compact, robust and scalable systems that integrate these two elements. This paper presents a low-noise transimpedance amplifier with integrated A/D conversion realized in CMOS 0.35 μm technology. The CMOS amplifier acquires currents in the range ±200 pA and ±20 nA, with 100 kHz bandwidth while dissipating 41 mW. An integrated digital offset compensation loop balances any voltage offsets from Ag/AgCl electrodes. The measured open-input input-referred noise current is as low as 4 fA/√Hz at ±200 pA range. The current amplifier is embedded in an integrated platform, together with a microfluidic device, for current recording from ion channels. Gramicidin-A, α-haemolysin and KcsA potassium channels have been used to prove both the platform and the current-to-digital converter.

A Low-Noise Transimpedance Amplifier for BLM-Based Ion Channel Recording

PubMed Central

Crescentini, Marco; Bennati, Marco; Saha, Shimul Chandra; Ivica, Josip; de Planque, Maurits; Morgan, Hywel; Tartagni, Marco

2016-01-01

High-throughput screening (HTS) using ion channel recording is a powerful drug discovery technique in pharmacology. Ion channel recording with planar bilayer lipid membranes (BLM) is scalable and has very high sensitivity. A HTS system based on BLM ion channel recording faces three main challenges: (i) design of scalable microfluidic devices; (ii) design of compact ultra-low-noise transimpedance amplifiers able to detect currents in the pA range with bandwidth >10 kHz; (iii) design of compact, robust and scalable systems that integrate these two elements. This paper presents a low-noise transimpedance amplifier with integrated A/D conversion realized in CMOS 0.35 μm technology. The CMOS amplifier acquires currents in the range ±200 pA and ±20 nA, with 100 kHz bandwidth while dissipating 41 mW. An integrated digital offset compensation loop balances any voltage offsets from Ag/AgCl electrodes. The measured open-input input-referred noise current is as low as 4 fA/√Hz at ±200 pA range. The current amplifier is embedded in an integrated platform, together with a microfluidic device, for current recording from ion channels. Gramicidin-A, α-haemolysin and KcsA potassium channels have been used to prove both the platform and the current-to-digital converter. PMID:27213382

Enhancing multi-step quantum state tomography by PhaseLift

NASA Astrophysics Data System (ADS)

Lu, Yiping; Zhao, Qing

2017-09-01

Multi-photon system has been studied by many groups, however the biggest challenge faced is the number of copies of an unknown state are limited and far from detecting quantum entanglement. The difficulty to prepare copies of the state is even more serious for the quantum state tomography. One possible way to solve this problem is to use adaptive quantum state tomography, which means to get a preliminary density matrix in the first step and revise it in the second step. In order to improve the performance of adaptive quantum state tomography, we develop a new distribution scheme of samples and extend it to three steps, that is to correct it once again based on the density matrix obtained in the traditional adaptive quantum state tomography. Our numerical results show that the mean square error of the reconstructed density matrix by our new method is improved to the level from 10-4 to 10-9 for several tested states. In addition, PhaseLift is also applied to reduce the required storage space of measurement operator.

About-face on face recognition ability and holistic processing.

PubMed

Richler, Jennifer J; Floyd, R Jackie; Gauthier, Isabel

2015-01-01

Previous work found a small but significant relationship between holistic processing measured with the composite task and face recognition ability measured by the Cambridge Face Memory Test (CFMT; Duchaine & Nakayama, 2006). Surprisingly, recent work using a different measure of holistic processing (Vanderbilt Holistic Face Processing Test [VHPT-F]; Richler, Floyd, & Gauthier, 2014) and a larger sample found no evidence for such a relationship. In Experiment 1 we replicate this unexpected result, finding no relationship between holistic processing (VHPT-F) and face recognition ability (CFMT). A key difference between the VHPT-F and other holistic processing measures is that unique face parts are used on each trial in the VHPT-F, unlike in other tasks where a small set of face parts repeat across the experiment. In Experiment 2, we test the hypothesis that correlations between the CFMT and holistic processing tasks are driven by stimulus repetition that allows for learning during the composite task. Consistent with our predictions, CFMT performance was correlated with holistic processing in the composite task when a small set of face parts repeated over trials, but not when face parts did not repeat. A meta-analysis confirms that relationships between the CFMT and holistic processing depend on stimulus repetition. These results raise important questions about what is being measured by the CFMT, and challenge current assumptions about why faces are processed holistically.

About-face on face recognition ability and holistic processing

PubMed Central

Richler, Jennifer J.; Floyd, R. Jackie; Gauthier, Isabel

2015-01-01

Previous work found a small but significant relationship between holistic processing measured with the composite task and face recognition ability measured by the Cambridge Face Memory Test (CFMT; Duchaine & Nakayama, 2006). Surprisingly, recent work using a different measure of holistic processing (Vanderbilt Holistic Face Processing Test [VHPT-F]; Richler, Floyd, & Gauthier, 2014) and a larger sample found no evidence for such a relationship. In Experiment 1 we replicate this unexpected result, finding no relationship between holistic processing (VHPT-F) and face recognition ability (CFMT). A key difference between the VHPT-F and other holistic processing measures is that unique face parts are used on each trial in the VHPT-F, unlike in other tasks where a small set of face parts repeat across the experiment. In Experiment 2, we test the hypothesis that correlations between the CFMT and holistic processing tasks are driven by stimulus repetition that allows for learning during the composite task. Consistent with our predictions, CFMT performance was correlated with holistic processing in the composite task when a small set of face parts repeated over trials, but not when face parts did not repeat. A meta-analysis confirms that relationships between the CFMT and holistic processing depend on stimulus repetition. These results raise important questions about what is being measured by the CFMT, and challenge current assumptions about why faces are processed holistically. PMID:26223027

Accurate step-FMCW ultrasound ranging and comparison with pulse-echo signaling methods

NASA Astrophysics Data System (ADS)

Natarajan, Shyam; Singh, Rahul S.; Lee, Michael; Cox, Brian P.; Culjat, Martin O.; Grundfest, Warren S.; Lee, Hua

2010-03-01

This paper presents a method setup for high-frequency ultrasound ranging based on stepped frequency-modulated continuous waves (FMCW), potentially capable of producing a higher signal-to-noise ratio (SNR) compared to traditional pulse-echo signaling. In current ultrasound systems, the use of higher frequencies (10-20 MHz) to enhance resolution lowers signal quality due to frequency-dependent attenuation. The proposed ultrasound signaling format, step-FMCW, is well-known in the radar community, and features lower peak power, wider dynamic range, lower noise figure and simpler electronics in comparison to pulse-echo systems. In pulse-echo ultrasound ranging, distances are calculated using the transmit times between a pulse and its subsequent echoes. In step-FMCW ultrasonic ranging, the phase and magnitude differences at stepped frequencies are used to sample the frequency domain. Thus, by taking the inverse Fourier transform, a comprehensive range profile is recovered that has increased immunity to noise over conventional ranging methods. Step-FMCW and pulse-echo waveforms were created using custom-built hardware consisting of an arbitrary waveform generator and dual-channel super heterodyne receiver, providing high SNR and in turn, accuracy in detection.

Dynamical coupled-channels study of pi N --> pi pi N reactions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kamano, Hiroyuki; Julia Diaz, Bruno; Lee, Tsung-Shung

2009-01-01

As a step toward performing a complete coupled-channels analysis of the world data of pi N, gamma^* N --> pi N, eta N, pi pi N reactions, the pi N --> pi pi N reactions are investigated starting with the dynamical coupled-channels model developed in Phys. Rev. C76, 065201 (2007). The channels included are pi N, eta N, and pi pi N which has pi Delta, rho N, and sigma N resonant components. The non-resonant amplitudes are generated from solving a set of coupled-channels equations with the meson-baryon potentials defined by effective Lagrangians. The resonant amplitudes are generated from 16more » bare excited nucleon (N^*) states which are dressed by the non-resonant interactions as constrained by the unitarity condition. The available total cross section data of pi^+ p --> pi^+ pi^+ n, pi^+ pi^0 and pi^- p --> pi^+ pi^- n, pi^- pi^0 n, pi^0 pi^0 n can be reproduced to a very large extent both in magnitudes and energy-dependence. Possible improvements of the model are investigated, in p« less

The temperature dependence of the BK channel activity - kinetics, thermodynamics, and long-range correlations.

PubMed

Wawrzkiewicz-Jałowiecka, Agata; Dworakowska, Beata; Grzywna, Zbigniew J

2017-10-01

Large-conductance, voltage dependent, Ca 2+ -activated potassium channels (BK) are transmembrane proteins that regulate many biological processes by controlling potassium flow across cell membranes. Here, we investigate to what extent temperature (in the range of 17-37°C with ΔT=5°C step) is a regulating parameter of kinetic properties of the channel gating and memory effect in the series of dwell-time series of subsequent channel's states, at membrane depolarization and hyperpolarization. The obtained results indicate that temperature affects strongly the BK channels' gating, but, counterintuitively, it exerts no effect on the long-range correlations, as measured by the Hurst coefficient. Quantitative differences between dependencies of appropriate channel's characteristics on temperature are evident for different regimes of voltage. Examining the characteristics of BK channel activity as a function of temperature allows to estimate the net activation energy (E act ) and changes of thermodynamic parameters (ΔH, ΔS, ΔG) by channel opening. Larger E act corresponds to the channel activity at membrane hyperpolarization. The analysis of entropy and enthalpy changes of closed to open channel's transition suggest the entropy-driven nature of the increase of open state probability during voltage activation and supports the hypothesis about the voltage-dependent geometry of the channel vestibule. Copyright © 2017 Elsevier B.V. All rights reserved.

Flow field induced particle accumulation inside droplets in rectangular channels.

PubMed

Hein, Michael; Moskopp, Michael; Seemann, Ralf

2015-07-07

Particle concentration is a basic operation needed to perform washing steps or to improve subsequent analysis in many (bio)-chemical assays. In this article we present field free, hydrodynamic accumulation of particles and cells in droplets flowing within rectangular micro-channels. Depending on droplet velocity, particles either accumulate at the rear of the droplet or are dispersed over the entire droplet cross-section. We show that the observed particle accumulation behavior can be understood by a coupling of particle sedimentation to the internal flow field of the droplet. The changing accumulation patterns are explained by a qualitative change of the internal flow field. The topological change of the internal flow field, however, is explained by the evolution of the droplet shape with increasing droplet velocity altering the friction with the channel walls. In addition, we demonstrate that accumulated particles can be concentrated, removing excess dispersed phase by splitting the droplet at a simple channel junction.

Antisense oligonucleotides suppress cell-volume-induced activation of chloride channels.

PubMed

Gschwentner, M; Nagl, U O; Wöll, E; Schmarda, A; Ritter, M; Paulmichl, M

1995-08-01

Cell volume regulation is an essential feature of most cells. After swelling in hypotonic media, the simultaneous activation of potassium and chloride channels is believed to be the initial, time-determining step in cell volume regulation. The activation of both pathways is functionally linked and enables the cells to lose ions and water, subsequently leading to cell shrinkage and readjustment of the initial volume. NIH 3T3 fibroblasts efficiently regulate their volume after swelling and bear chloride channels that are activated by decreasing extracellular osmolarity. The chloride current elicited in these cells after swelling is reminiscent of the current found in oocytes expressing an outwardly rectifying chloride current termed ICln. Introduction of antisense oligodeoxynucleotides complementary to the first 30 nucleotides of the coding region of the ICln channel into NIH 3T3 fibroblasts suppresses the activation of the swelling-induced chloride current. The experiments directly demonstrate an unambiguous link between a volume-activated chloride current and a cloned protein involved in chloride transport.

On the Transition from Initial Leader to Stepped Leader in Negative Cloud-to-ground Lightning

NASA Astrophysics Data System (ADS)

Stolzenburg, M.; Marshall, T. C.; Karunarathne, S.; Orville, R. E.

2017-12-01

High-speed video and electric field change (E-change) data are used to describe the first 5 ms of a natural negative cloud-to-ground (CG) flash. These observations reveal differences in appearance of both the video luminosity and the E-change pulses before the leader transitions to propagating as a negative stepped leader (SL). During the initial breakdown (IB) stage, the initial leader advances intermittently forward in jumps of 78-175 m, at intervals of 100-280 μs, and in separate bursts that are bright for a few 20-μs video frames. The IB pulses accompanying these luminosity bursts have long duration, large amplitude, and a characteristic bipolar shape in nearby E-change observations. In the time between IB pulses, the initial leader is very dim or not visible during the earliest 1-2 ms of the IB stage. Over the next few milliseconds, the leader propagation transitions to an early SL phase, in which the leader tips advance 20-59 m forward at more regular intervals of 40-80 μs during relatively dim and brief steps. In the E-change data, the accompanying SL pulses have very short duration, small amplitude, and are typically unipolar. These data indicate that when the entire initial leader length behind the lower end begins to remain illuminated between bursts, the propagation mode changes from IB bursts to SL steps, and the IB stage ends. Additional differences in initial leader character are evident during the return stroke, as its luminosity speed decreases sharply upon reaching the topmost initial leader section of the channel, and that section of channel does not saturate the video intensity. Results of these analyses support a prior hypothesis that the early initial leader development occurs in the absence of a continuously hot channel, and consequently, the initial leader propagation is unlike the self-propagating advance of the later stepped leader.

Accounting for one-channel depletion improves missing value imputation in 2-dye microarray data.

PubMed

Ritz, Cecilia; Edén, Patrik

2008-01-19

For 2-dye microarray platforms, some missing values may arise from an un-measurably low RNA expression in one channel only. Information of such "one-channel depletion" is so far not included in algorithms for imputation of missing values. Calculating the mean deviation between imputed values and duplicate controls in five datasets, we show that KNN-based imputation gives a systematic bias of the imputed expression values of one-channel depleted spots. Evaluating the correction of this bias by cross-validation showed that the mean square deviation between imputed values and duplicates were reduced up to 51%, depending on dataset. By including more information in the imputation step, we more accurately estimate missing expression values.

Effects of walking speed on the step-by-step control of step width.

PubMed

Stimpson, Katy H; Heitkamp, Lauren N; Horne, Joscelyn S; Dean, Jesse C

2018-02-08

Young, healthy adults walking at typical preferred speeds use step-by-step adjustments of step width to appropriately redirect their center of mass motion and ensure mediolateral stability. However, it is presently unclear whether this control strategy is retained when walking at the slower speeds preferred by many clinical populations. We investigated whether the typical stabilization strategy is influenced by walking speed. Twelve young, neurologically intact participants walked on a treadmill at a range of prescribed speeds (0.2-1.2 m/s). The mediolateral stabilization strategy was quantified as the proportion of step width variance predicted by the mechanical state of the pelvis throughout a step (calculated as R 2 magnitude from a multiple linear regression). Our ability to accurately predict the upcoming step width increased over the course of a step. The strength of the relationship between step width and pelvis mechanics at the start of a step was reduced at slower speeds. However, these speed-dependent differences largely disappeared by the end of a step, other than at the slowest walking speed (0.2 m/s). These results suggest that mechanics-dependent adjustments in step width are a consistent component of healthy gait across speeds and contexts. However, slower walking speeds may ease this control by allowing mediolateral repositioning of the swing leg to occur later in a step, thus encouraging slower walking among clinical populations with limited sensorimotor control. Published by Elsevier Ltd.

Radio-frequency response of single pores and artificial ion channels

NASA Astrophysics Data System (ADS)

Kim, H. S.; Ramachandran, S.; Stava, E.; van der Weide, D. W.; Blick, R. H.

2011-09-01

Intercellular communication relies on ion channels and pores in cell membranes. These protein-formed channels enable the exchange of ions and small molecules to electrically and/or chemically interact with the cells. Traditionally, recordings on single-ion channels and pores are performed in the dc regime, due to the extremely high impedance of these molecular junctions. This paper is intended as an introduction to radio-frequency (RF) recordings of single-molecule junctions in bilipid membranes. First, we demonstrate how early approaches to using microwave circuitry as readout devices for ion channel formation were realized. The second step will then focus on how to engineer microwave coupling into the high-impedance channel by making use of bio-compatible micro-coaxial lines. We then demonstrate integration of an ultra-broadband microwave circuit for the direct sampling of single α-hemolysin pores in a suspended bilipid membrane. Simultaneous direct current recordings reveal that we can monitor and correlate the RF transmission signal. This enables us to relate the open-close states of the direct current to the RF signal. Altogether, our experiments lay the ground for an RF-readout technique to perform real-time in vitro recordings of pores. The technique thus holds great promise for research and drug screening applications. The possible enhancement of sampling rates of single channels and pores by the large recording bandwidth will allow us to track the passage of single ions.

Multi-Time Step Service Restoration for Advanced Distribution Systems and Microgrids

DOE PAGES

Chen, Bo; Chen, Chen; Wang, Jianhui; ...

2017-07-07

Modern power systems are facing increased risk of disasters that can cause extended outages. The presence of remote control switches (RCSs), distributed generators (DGs), and energy storage systems (ESS) provides both challenges and opportunities for developing post-fault service restoration methodologies. Inter-temporal constraints of DGs, ESS, and loads under cold load pickup (CLPU) conditions impose extra complexity on problem formulation and solution. In this paper, a multi-time step service restoration methodology is proposed to optimally generate a sequence of control actions for controllable switches, ESSs, and dispatchable DGs to assist the system operator with decision making. The restoration sequence is determinedmore » to minimize the unserved customers by energizing the system step by step without violating operational constraints at each time step. The proposed methodology is formulated as a mixed-integer linear programming (MILP) model and can adapt to various operation conditions. Furthermore, the proposed method is validated through several case studies that are performed on modified IEEE 13-node and IEEE 123-node test feeders.« less

Multi-Time Step Service Restoration for Advanced Distribution Systems and Microgrids

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, Bo; Chen, Chen; Wang, Jianhui

Modern power systems are facing increased risk of disasters that can cause extended outages. The presence of remote control switches (RCSs), distributed generators (DGs), and energy storage systems (ESS) provides both challenges and opportunities for developing post-fault service restoration methodologies. Inter-temporal constraints of DGs, ESS, and loads under cold load pickup (CLPU) conditions impose extra complexity on problem formulation and solution. In this paper, a multi-time step service restoration methodology is proposed to optimally generate a sequence of control actions for controllable switches, ESSs, and dispatchable DGs to assist the system operator with decision making. The restoration sequence is determinedmore » to minimize the unserved customers by energizing the system step by step without violating operational constraints at each time step. The proposed methodology is formulated as a mixed-integer linear programming (MILP) model and can adapt to various operation conditions. Furthermore, the proposed method is validated through several case studies that are performed on modified IEEE 13-node and IEEE 123-node test feeders.« less

A MULTIPLE GRID ALGORITHM FOR ONE-DIMENSIONAL TRANSIENT OPEN CHANNEL FLOWS. (R825200)

EPA Science Inventory

Numerical modeling of open channel flows with shocks using explicit finite difference schemes is constrained by the choice of time step, which is limited by the CFL stability criteria. To overcome this limitation, in this work we introduce the application of a multiple grid al...

An external sodium ion binding site controls allosteric gating in TRPV1 channels

PubMed Central

Jara-Oseguera, Andres; Bae, Chanhyung; Swartz, Kenton J

2016-01-01

TRPV1 channels in sensory neurons are integrators of painful stimuli and heat, yet how they integrate diverse stimuli and sense temperature remains elusive. Here, we show that external sodium ions stabilize the TRPV1 channel in a closed state, such that removing the external ion leads to channel activation. In studying the underlying mechanism, we find that the temperature sensors in TRPV1 activate in two steps to favor opening, and that the binding of sodium to an extracellular site exerts allosteric control over temperature-sensor activation and opening of the pore. The binding of a tarantula toxin to the external pore also exerts control over temperature-sensor activation, whereas binding of vanilloids influences temperature-sensitivity by largely affecting the open/closed equilibrium. Our results reveal a fundamental role of the external pore in the allosteric control of TRPV1 channel gating and provide essential constraints for understanding how these channels can be tuned by diverse stimuli. DOI: http://dx.doi.org/10.7554/eLife.13356.001 PMID:26882503

Verification of Embolic Channel Causing Blindness Following Filler Injection.

PubMed

Tansatit, Tanvaa; Moon, Hyoung Jin; Apinuntrum, Prawit; Phetudom, Thavorn

2015-02-01

Ocular complications following cosmetic filler injections are serious situations. This study provided scientific evidence that filler in the facial and the superficial temporal arteries could enter into the orbits and the globes on both sides. We demonstrated the existence of an embolic channel connecting the arterial system of the face to the ophthalmic artery. After the removal of the ocular contents from both eyes, liquid dye was injected into the cannulated channel of the superficial temporal artery in six soft embalmed cadavers and different color dye was injected into the facial artery on both sides successively. The interior sclera was monitored for dye oozing from retrograde ophthalmic perfusion. Among all 12 globes, dye injections from the 12 superficial temporal arteries entered ipsilateral globes in three and the contralateral globe in two arteries. Dye from the facial artery was infused into five ipsilateral globes and in three contralateral globes. Dye injections of two facial arteries in the same cadaver resulted in bilateral globe staining but those of the superficial temporal arteries did not. Direct communications between the same and different arteries of the four cannulated arteries were evidenced by dye dripping from the cannulating needle hubs in 14 of 24 injected arteries. Compression of the orbital rim at the superior nasal corner retarded ocular infusion in 11 of 14 arterial injections. Under some specific conditions favoring embolism, persistent interarterial anastomoses between the face and the eye allowed filler emboli to flow into the globe causing ocular complications.

Carbon-Type Analysis and Comparison of Original and Reblended FACE Diesel Fuels (FACE 2, FACE 4, and FACE 7)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bays, J. Timothy; King, David L.; O'Hagan, Molly J.