Sample records for fail safe principles

  1. 30 CFR 77.312 - Fail safe monitoring systems.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Fail safe monitoring systems. 77.312 Section 77... Thermal Dryers § 77.312 Fail safe monitoring systems. Thermal dryer systems and controls shall be protected by a fail safe monitoring system which will safely shut down the system and any related equipment...

  2. 30 CFR 77.312 - Fail safe monitoring systems.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Fail safe monitoring systems. 77.312 Section 77... Thermal Dryers § 77.312 Fail safe monitoring systems. Thermal dryer systems and controls shall be protected by a fail safe monitoring system which will safely shut down the system and any related equipment...

  3. 30 CFR 77.312 - Fail safe monitoring systems.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Fail safe monitoring systems. 77.312 Section 77... Thermal Dryers § 77.312 Fail safe monitoring systems. Thermal dryer systems and controls shall be protected by a fail safe monitoring system which will safely shut down the system and any related equipment...

  4. 30 CFR 77.312 - Fail safe monitoring systems.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Fail safe monitoring systems. 77.312 Section 77... Thermal Dryers § 77.312 Fail safe monitoring systems. Thermal dryer systems and controls shall be protected by a fail safe monitoring system which will safely shut down the system and any related equipment...

  5. 30 CFR 77.312 - Fail safe monitoring systems.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Fail safe monitoring systems. 77.312 Section 77... Thermal Dryers § 77.312 Fail safe monitoring systems. Thermal dryer systems and controls shall be protected by a fail safe monitoring system which will safely shut down the system and any related equipment...

  6. Rational use of analgesic combinations.

    PubMed

    Phero, James C; Becker, Daniel

    2002-10-01

    Careful selection of an effective analgesic regimen based on the amount and type of pain the patient is expected to have can prevent the stress and anxiety associated with breakthrough pain. When analgesics fail, it is not unusual for patients to go to desperate lengths to seek relief. The clinician can and should develop a variety of effective, safe analgesic regimens based on estimates of anticipated pain intensity that apply sound pharmacologic principles.

  7. 30 CFR 75.803 - Fail safe ground check circuits on high-voltage resistance grounded systems.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Fail safe ground check circuits on high-voltage... High-Voltage Distribution § 75.803 Fail safe ground check circuits on high-voltage resistance grounded... shall include a fail safe ground check circuit to monitor continuously the grounding circuit to assure...

  8. 30 CFR 75.803 - Fail safe ground check circuits on high-voltage resistance grounded systems.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Fail safe ground check circuits on high-voltage... High-Voltage Distribution § 75.803 Fail safe ground check circuits on high-voltage resistance grounded... shall include a fail safe ground check circuit to monitor continuously the grounding circuit to assure...

  9. 30 CFR 75.803 - Fail safe ground check circuits on high-voltage resistance grounded systems.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Fail safe ground check circuits on high-voltage... High-Voltage Distribution § 75.803 Fail safe ground check circuits on high-voltage resistance grounded... shall include a fail safe ground check circuit to monitor continuously the grounding circuit to assure...

  10. 30 CFR 75.803 - Fail safe ground check circuits on high-voltage resistance grounded systems.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Fail safe ground check circuits on high-voltage... High-Voltage Distribution § 75.803 Fail safe ground check circuits on high-voltage resistance grounded... shall include a fail safe ground check circuit to monitor continuously the grounding circuit to assure...

  11. 30 CFR 77.803 - Fail safe ground check circuits on high-voltage resistance grounded systems.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Fail safe ground check circuits on high-voltage... WORK AREAS OF UNDERGROUND COAL MINES Surface High-Voltage Distribution § 77.803 Fail safe ground check..., resistance grounded systems shall include a fail safe ground check circuit or other no less effective device...

  12. 30 CFR 77.803 - Fail safe ground check circuits on high-voltage resistance grounded systems.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Fail safe ground check circuits on high-voltage... WORK AREAS OF UNDERGROUND COAL MINES Surface High-Voltage Distribution § 77.803 Fail safe ground check..., resistance grounded systems shall include a fail safe ground check circuit or other no less effective device...

  13. 30 CFR 77.803 - Fail safe ground check circuits on high-voltage resistance grounded systems.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Fail safe ground check circuits on high-voltage... WORK AREAS OF UNDERGROUND COAL MINES Surface High-Voltage Distribution § 77.803 Fail safe ground check..., resistance grounded systems shall include a fail safe ground check circuit or other no less effective device...

  14. 30 CFR 77.803 - Fail safe ground check circuits on high-voltage resistance grounded systems.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Fail safe ground check circuits on high-voltage... WORK AREAS OF UNDERGROUND COAL MINES Surface High-Voltage Distribution § 77.803 Fail safe ground check..., resistance grounded systems shall include a fail safe ground check circuit or other no less effective device...

  15. A fail-safe CMOS logic gate

    NASA Technical Reports Server (NTRS)

    Bobin, V.; Whitaker, S.

    1990-01-01

    This paper reports a design technique to make Complex CMOS Gates fail-safe for a class of faults. Two classes of faults are defined. The fail-safe design presented has limited fault-tolerance capability. Multiple faults are also covered.

  16. SafeNet: a methodology for integrating general-purpose unsafe devices in safe-robot rehabilitation systems.

    PubMed

    Vicentini, Federico; Pedrocchi, Nicola; Malosio, Matteo; Molinari Tosatti, Lorenzo

    2014-09-01

    Robot-assisted neurorehabilitation often involves networked systems of sensors ("sensory rooms") and powerful devices in physical interaction with weak users. Safety is unquestionably a primary concern. Some lightweight robot platforms and devices designed on purpose include safety properties using redundant sensors or intrinsic safety design (e.g. compliance and backdrivability, limited exchange of energy). Nonetheless, the entire "sensory room" shall be required to be fail-safe and safely monitored as a system at large. Yet, sensor capabilities and control algorithms used in functional therapies require, in general, frequent updates or re-configurations, making a safety-grade release of such devices hardly sustainable in cost-effectiveness and development time. As such, promising integrated platforms for human-in-the-loop therapies could not find clinical application and manufacturing support because of lacking in the maintenance of global fail-safe properties. Under the general context of cross-machinery safety standards, the paper presents a methodology called SafeNet for helping in extending the safety rate of Human Robot Interaction (HRI) systems using unsafe components, including sensors and controllers. SafeNet considers, in fact, the robotic system as a device at large and applies the principles of functional safety (as in ISO 13489-1) through a set of architectural procedures and implementation rules. The enabled capability of monitoring a network of unsafe devices through redundant computational nodes, allows the usage of any custom sensors and algorithms, usually planned and assembled at therapy planning-time rather than at platform design-time. A case study is presented with an actual implementation of the proposed methodology. A specific architectural solution is applied to an example of robot-assisted upper-limb rehabilitation with online motion tracking. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  17. Anti-backlash drive systems for multi-degree freedom devices

    DOEpatents

    Tsai, Lung-Wen; Chang, Sun-Lai

    1993-01-01

    A new and innovative concept for the control of backlash in gear-coupled transmission mechanisms. The concept utilizes redundant unidirectional drives to assure positive coupling of gear meshes at all times. Based on this concept, a methodology for the enumeration of admissible redundant-drive backlash-free robotic mechanisms has been established. Some typical two- and three-DOF mechanisms are disclosed. Furthermore, actuator torques have been derived as functions of either joint torques or end-effector dynamic performance requirements. A redundantly driven gear coupled transmission mechanism manipulator has a fail-safe advantage in that, except of the loss of backlash control, it can continue to function when one of its actuators fails. A two-DOF backlash-free arm has been reduced to practice to demonstrate the principle.

  18. Investigation of safe-life fail-safe criteria for the space shuttle

    NASA Technical Reports Server (NTRS)

    1972-01-01

    An investigation was made to determine the effects of a safe-life design approach and a fail-safe design approach on the space shuttle booster vehicle structure, and to recommend any changes to the structural design criteria. Two configurations of the booster vehicle were considered, one incorporating a delta wing (B-9U configuration) and the other a swept wing (B-16B configuration). Several major structural components of the booster were studied to determine the fatigue life, safe-life, and fail-safe capabilities of the baseline design. Each component was investigated to determine the practicability of applying a safe-life or fail-safe design philosophy, the changes such design approaches might require, and the impact of these changes on weight, cost, development plans, and performance.

  19. On the calculation of low-thrust fail-safe trajectories

    NASA Technical Reports Server (NTRS)

    Sauer, C. G., Jr.

    1975-01-01

    A guidance algorithm is developed for a low-thrust spacecraft such that target intercept is possible in spite of premature thrust termination along the trajectory. Such a trajectory is called a 'fail-safe' trajectory and the spacecraft thrust is utilized to minimize the relative target-spacecraft approach speed. The fail-safe guidance algorithm is solved using the concept of a critical thrust plane and a non-critical thrust direction. Several examples of fail-safe guidance are presented for a solar-electric propulsion flyby mission to the comet Encke.

  20. 30 CFR 77.902-1 - Fail safe ground check circuits; maximum voltage.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Fail safe ground check circuits; maximum voltage. 77.902-1 Section 77.902-1 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF... OF UNDERGROUND COAL MINES Low- and Medium-Voltage Alternating Current Circuits § 77.902-1 Fail safe...

  1. 30 CFR 77.902-1 - Fail safe ground check circuits; maximum voltage.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Fail safe ground check circuits; maximum voltage. 77.902-1 Section 77.902-1 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF... OF UNDERGROUND COAL MINES Low- and Medium-Voltage Alternating Current Circuits § 77.902-1 Fail safe...

  2. 30 CFR 77.803-1 - Fail safe ground check circuits; maximum voltage.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Fail safe ground check circuits; maximum voltage. 77.803-1 Section 77.803-1 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF... OF UNDERGROUND COAL MINES Surface High-Voltage Distribution § 77.803-1 Fail safe ground check...

  3. 30 CFR 77.803-1 - Fail safe ground check circuits; maximum voltage.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Fail safe ground check circuits; maximum voltage. 77.803-1 Section 77.803-1 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF... OF UNDERGROUND COAL MINES Surface High-Voltage Distribution § 77.803-1 Fail safe ground check...

  4. 30 CFR 77.902-1 - Fail safe ground check circuits; maximum voltage.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Fail safe ground check circuits; maximum voltage. 77.902-1 Section 77.902-1 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF... OF UNDERGROUND COAL MINES Low- and Medium-Voltage Alternating Current Circuits § 77.902-1 Fail safe...

  5. 30 CFR 77.803-1 - Fail safe ground check circuits; maximum voltage.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Fail safe ground check circuits; maximum voltage. 77.803-1 Section 77.803-1 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF... OF UNDERGROUND COAL MINES Surface High-Voltage Distribution § 77.803-1 Fail safe ground check...

  6. 77 FR 21422 - Airworthiness Directives; The Boeing Company Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-10

    ... the fail-safe interlayer of certain No. 2 and No. 3 glass windows, which could result in loss of the... would hinder the internal or external detailed inspections for fail-safe interlayer cracks, glass pane... this AD only if the non-clear damage hinders the inspection for fail-safe interlayer cracks, glass pane...

  7. 30 CFR 77.803-1 - Fail safe ground check circuits; maximum voltage.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Fail safe ground check circuits; maximum... OF UNDERGROUND COAL MINES Surface High-Voltage Distribution § 77.803-1 Fail safe ground check circuits; maximum voltage. The maximum voltage used for ground check circuits under § 77.803 shall not...

  8. 30 CFR 77.803-1 - Fail safe ground check circuits; maximum voltage.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Fail safe ground check circuits; maximum... OF UNDERGROUND COAL MINES Surface High-Voltage Distribution § 77.803-1 Fail safe ground check circuits; maximum voltage. The maximum voltage used for ground check circuits under § 77.803 shall not...

  9. Anti-backlash drive systems for multi-degree freedom devices

    DOEpatents

    Lungwen Tsai; Sunlai Chang.

    1993-09-14

    A new and innovative concept is described for the control of backlash in gear-coupled transmission mechanisms. The concept utilizes redundant unidirectional drives to assure positive coupling of gear meshes at all times. Based on this concept, a methodology for the enumeration of admissible redundant-drive backlash-free robotic mechanisms has been established. Some typical two- and three-DOF mechanisms are disclosed. Furthermore, actuator torques have been derived as functions of either joint torques or end-effector dynamic performance requirements. A redundantly driven gear coupled transmission mechanism manipulator has a fail-safe advantage in that, except of the loss of backlash control, it can continue to function when one of its actuators fails. A two-DOF backlash-free arm has been reduced to practice to demonstrate the principle. 20 figures.

  10. Study of fail-safe abort system for an actively cooled hypersonic aircraft, volume 2

    NASA Technical Reports Server (NTRS)

    Peeples, M. E.; Herring, R. L.

    1976-01-01

    Conceptual designs of a fail-safe abort system for hydrogen fueled actively cooled high speed aircraft are examined. The fail-safe concept depends on basically three factors: (1) a reliable method of detecting a failure or malfunction in the active cooling system, (2) the optimization of abort trajectories which minimize the descent heat load to the aircraft, and (3) fail-safe thermostructural concepts to minimize both the weight and the maximum temperature the structure will reach during descent. These factors are examined and promising approaches are evaluated based on weight, reliability, ease of manufacture and cost.

  11. 76 FR 10288 - Airworthiness Directives; The Boeing Company Model 767-200, -300, -300F, and -400ER Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-24

    ... and corrosion to an area within five inches of the fail-safe strap. Revision 2 of this service.... The existing AD currently requires inspections to detect cracking or corrosion of the fail-safe straps... corrective actions. Since we issued that AD, we have received additional reports of cracks in 51 fail-safe...

  12. Study of a fail-safe abort system for an actively cooled hypersonic aircraft. Volume 1: Technical summary

    NASA Technical Reports Server (NTRS)

    Pirello, C. J.; Herring, R. L.

    1976-01-01

    Conceptual designs of a fail-safe abort system for hydrogen fueled actively cooled high speed aircraft are examined. The fail-safe concept depends on basically three factors: (1) a reliable method of detecting a failure or malfunction in the active cooling system, (2) the optimization of abort trajectories which minimize the descent heat load to the aircraft, and (3) fail-safe thermostructural concepts to minimize both the weight and the maximum temperature the structure will reach during descent. These factors are examined and promising approaches are evaluated based on weight, reliability, ease of manufacture and cost.

  13. 29 CFR 1910.179 - Overhead and gantry cranes.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... adequately guarded or isolated. (40) Fail-safe means a provision designed to automatically stop or safely... shall be capable of maintaining safe lowering speeds of rated loads. (ii) The control braking means... the crane operator. (viii) Automatic cranes shall be so designed that all motions shall fail-safe if...

  14. 76 FR 38074 - Airworthiness Directives; The Boeing Company Model 747-100, 747-100B, 747-200B, 747-200C, 747...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-29

    ... withstand fail-safe loads. DATES: We must receive comments on this proposed AD by August 15, 2011. ADDRESSES... pressurization and the inability of the airplane fuselage to withstand fail-safe loads. Actions Since Existing AD... withstand fail-safe loads. Compliance (f) You are responsible for having the actions required by this AD...

  15. 77 FR 26663 - Airworthiness Directives; The Boeing Company Model 767-200, -300, -300F, and -400ER Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-07

    ... removing corrosion from fail-safe straps. We have received Boeing Service Bulletin 767-53A0100, Revision 3.... That AD currently requires inspections to detect cracking or corrosion of the fail-safe straps between... cracks in 51 fail-safe straps on 41 airplanes; we have also received a report of a crack found in the ``T...

  16. 76 FR 19278 - Airworthiness Directives; The Boeing Company Model 747-100, 747-100B, 747-100B SUD, 747-200B, 747...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-07

    ... are proposing this AD to detect and correct cracking in the fail-safe interlayer of certain No. 2 and... to detect and correct cracking in the fail-safe interlayer of certain No. 2 and No. 3 glass windows... cracking in the fail-safe interlayer of certain No. 2 and No. 3 glass windows, which could result in loss...

  17. Fail-safe reactivity compensation method for a nuclear reactor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nygaard, Erik T.; Angelo, Peter L.; Aase, Scott B.

    The present invention relates generally to the field of compensation methods for nuclear reactors and, in particular to a method for fail-safe reactivity compensation in solution-type nuclear reactors. In one embodiment, the fail-safe reactivity compensation method of the present invention augments other control methods for a nuclear reactor. In still another embodiment, the fail-safe reactivity compensation method of the present invention permits one to control a nuclear reaction in a nuclear reactor through a method that does not rely on moving components into or out of a reactor core, nor does the method of the present invention rely on themore » constant repositioning of control rods within a nuclear reactor in order to maintain a critical state.« less

  18. New Developments in FPGA: SEUs and Fail-Safe Strategies from the NASA Goddard Perspective

    NASA Technical Reports Server (NTRS)

    Berg, Melanie D.; Label, Kenneth A.; Pellish, Jonathan

    2016-01-01

    It has been shown that, when exposed to radiation environments, each Field Programmable Gate Array (FPGA) device has unique error signatures. Subsequently, fail-safe and mitigation strategies will differ per FPGA type. In this session several design approaches for safe systems will be presented. It will also explore the benefits and limitations of several mitigation techniques. The intention of the presentation is to provide information regarding FPGA types, their susceptibilities, and proven fail-safe strategies; so that users can select appropriate mitigation and perform the required trade for system insertion. The presentation will describe three types of FPGA devices and their susceptibilities in radiation environments.

  19. New Developments in FPGA: SEUs and Fail-Safe Strategies from the NASA Goddard Perspective

    NASA Technical Reports Server (NTRS)

    Berg, Melanie D.; LaBel, Kenneth; Pellish, Jonathan

    2015-01-01

    It has been shown that, when exposed to radiation environments, each Field Programmable Gate Array (FPGA) device has unique error signatures. Subsequently, fail-safe and mitigation strategies will differ per FPGA type. In this session several design approaches for safe systems will be presented. It will also explore the benefits and limitations of several mitigation techniques. The intention of the presentation is to provide information regarding FPGA types, their susceptibilities, and proven fail-safe strategies; so that users can select appropriate mitigation and perform the required trade for system insertion. The presentation will describe three types of FPGA devices and their susceptibilities in radiation environments.

  20. New Developments in FPGA Devices: SEUs and Fail-Safe Strategies from the NASA Goddard Perspective

    NASA Technical Reports Server (NTRS)

    Berg, Melanie; LaBel, Kenneth; Pellish, Jonathan

    2016-01-01

    It has been shown that, when exposed to radiation environments, each Field Programmable Gate Array (FPGA) device has unique error signatures. Subsequently, fail-safe and mitigation strategies will differ per FPGA type. In this session several design approaches for safe systems will be presented. It will also explore the benefits and limitations of several mitigation techniques. The intention of the presentation is to provide information regarding FPGA types, their susceptibilities, and proven fail-safe strategies; so that users can select appropriate mitigation and perform the required trade for system insertion. The presentation will describe three types of FPGA devices and their susceptibilities in radiation environments.

  1. HOME - An application of fault-tolerant techniques and system self-testing. [independent computer for helicopter flight control command monitoring

    NASA Technical Reports Server (NTRS)

    Holden, D. G.

    1975-01-01

    Hard Over Monitoring Equipment (HOME) has been designed to complement and enhance the flight safety of a flight research helicopter. HOME is an independent, highly reliable, and fail-safe special purpose computer that monitors the flight control commands issued by the flight control computer of the helicopter. In particular, HOME detects the issuance of a hazardous hard-over command for any of the four flight control axes and transfers the control of the helicopter to the flight safety pilot. The design of HOME incorporates certain reliability and fail-safe enhancement design features, such as triple modular redundancy, majority logic voting, fail-safe dual circuits, independent status monitors, in-flight self-test, and a built-in preflight exerciser. The HOME design and operation is described with special emphasis on the reliability and fail-safe aspects of the design.

  2. Fail-safe system for activity cooled supersonic and hypersonic aircraft. [using liquid hydrogen fuel

    NASA Technical Reports Server (NTRS)

    Jones, R. A.; Braswell, D. O.; Richie, C. B.

    1975-01-01

    A fail-safe-system concept was studied as an alternative to a redundant active cooling system for supersonic and hypersonic aircraft which use the heat sink of liquid-hydrogen fuel for cooling the aircraft structure. This concept consists of an abort maneuver by the aircraft and a passive thermal protection system (TPS) for the aircraft skin. The abort manuever provides a low-heat-load descent from normal cruise speed to a lower speed at which cooling is unnecessary, and the passive TPS allows the aircraft skin to absorb the abort heat load without exceeding critical skin temperature. On the basis of results obtained, it appears that this fail-safe-system concept warrants further consideration, inasmuch as a fail-safe system could possibly replace a redundant active cooling system with no increase in weight and would offer other potential advantages.

  3. To fail is human: remediating remediation in medical education.

    PubMed

    Kalet, Adina; Chou, Calvin L; Ellaway, Rachel H

    2017-12-01

    Remediating failing medical learners has traditionally been a craft activity responding to individual learner and remediator circumstances. Although there have been moves towards more systematic approaches to remediation (at least at the institutional level), these changes have tended to focus on due process and defensibility rather than on educational principles. As remediation practice evolves, there is a growing need for common theoretical and systems-based perspectives to guide this work. This paper steps back from the practicalities of remediation practice to take a critical systems perspective on remediation in contemporary medical education. In doing so, the authors acknowledge the complex interactions between institutional, professional, and societal forces that are both facilitators of and barriers to effective remediation practices. The authors propose a model that situates remediation within the contexts of society as a whole, the medical profession, and medical education institutions. They also outline a number of recommendations to constructively align remediation principles and practices, support a continuum of remediation practices, destigmatize remediation, and develop institutional communities of practice in remediation. Medical educators must embrace a responsible and accountable systems-level approach to remediation if they are to meet their obligations to provide a safe and effective physician workforce.

  4. Fluid check valve has fail-safe feature

    NASA Technical Reports Server (NTRS)

    Gaul, L. C.

    1965-01-01

    Check valve ensures unidirectional fluid flow and, in case of failure, vents the downstream fluid to the atmosphere and gives a positive indication of malfunction. This dual valve consists of a master check valve and a fail-safe valve.

  5. Study of a fail-safe abort system for an actively cooled hypersonic aircraft: Computer program documentation

    NASA Technical Reports Server (NTRS)

    Haas, L. A., Sr.

    1976-01-01

    The Fail-Safe Abort System TEMPerature Analysis Program, (FASTEMP), user's manual is presented. This program was used to analyze fail-safe abort systems for an actively cooled hypersonic aircraft. FASTEMP analyzes the steady state or transient temperature response of a thermal model defined in rectangular, cylindrical, conical and/or spherical coordinate system. FASTEMP provides the user with a large selection of subroutines for heat transfer calculations. The various modes of heat transfer available from these subroutines are: heat storage, conduction, radiation, heat addition or generation, convection, and fluid flow.

  6. Automatic protective vent has fail-safe feature

    NASA Technical Reports Server (NTRS)

    Dameron, C. E.

    1966-01-01

    Delayed vent valve system in a mechanical backing pump in a vacuum system allows the pneumatic foreline valve to seal before the pump vent opens. The system is designed to be fail-safe and operate even though there is loss of electrical power.

  7. Fail-safe bidirectional valve driver

    NASA Technical Reports Server (NTRS)

    Fujimoto, H.

    1974-01-01

    Cross-coupled diodes are added to commonly used bidirectional valve driver circuit to protect circuit and power supply. Circuit may be used in systems requiring fail-safe bidirectional valve operation, particularly in chemical- and petroleum-processing control systems and computer-controlled hydraulic or pneumatic systems.

  8. Performance of a fail-safe system to follow up abnormal mammograms in primary care.

    PubMed

    Grossman, Ellie; Phillips, Russell S; Weingart, Saul N

    2010-09-01

    Missed and delayed breast cancer diagnoses are major sources of potential harm to patients and medical malpractice liability in the United States. Follow-up of abnormal mammogram results is an essential but challenging component of safe breast care. To explore the value of an inexpensive method to follow up abnormal test results, we examined a paper-based fail-safe system. We examined a fail-safe system used to follow up abnormal mammograms at a primary care practice at an urban teaching hospital. We analyzed all abnormal mammogram reports and clinicians' responses to follow-up reminders. We characterized potential lapses identified in this system and used regression models to identify patient, provider, and test result characteristics associated with such lapses. Clinicians responded to fail-safe reminders for 92% of 948 abnormal mammograms. Clinicians reported that they were unaware of the abnormal result in 8% of cases and that there was no follow-up plan in place for 3% of cases. Clinicians with more years of experience were more likely to be aware of the abnormal result (odds of being unaware per incremental year in practice, 0.92; 95% confidence interval, 0.88-0.97) and were more likely to have a follow-up plan. A paper-based fail-safe system for abnormal mammograms is feasible in a primary care practice. However, special care is warranted to ensure full clinician adherence and address staff transitions and trainee-related issues.

  9. 77 FR 29857 - Airworthiness Directives; The Boeing Company Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-21

    ... of cabin pressurization and the inability of the fuselage to withstand fail-safe loads. DATES: This... cabin pressurization and the inability of the fuselage to withstand fail-safe loads. (f) Compliance You... reference of certain publications listed in the AD as of June 25, 2012. ADDRESSES: For service information...

  10. 76 FR 82210 - Airworthiness Directives; The Boeing Company Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-30

    ... fuse pins that can fail earlier than the previously determined safe life limit of the pins. A fractured... retract actuator fuse pins that can fail earlier than previously determined safe life limit of the pins. A... Friday, except Federal holidays. For service information identified in this proposed AD, contact Boeing...

  11. 77 FR 37781 - Airworthiness Directives; The Boeing Company Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-25

    ... actuator fuse pins that can fail earlier than the previously determined safe life limit of the pins. A... that can fail earlier than the previously determined safe life limit of the pins. A fractured retract... July 30, 2012. ADDRESSES: For service information identified in this AD, contact Boeing Commercial...

  12. Adaptive voting computer system

    NASA Technical Reports Server (NTRS)

    Koczela, L. J.; Wilgus, D. S. (Inventor)

    1974-01-01

    A computer system is reported that uses adaptive voting to tolerate failures and operates in a fail-operational, fail-safe manner. Each of four computers is individually connected to one of four external input/output (I/O) busses which interface with external subsystems. Each computer is connected to receive input data and commands from the other three computers and to furnish output data commands to the other three computers. An adaptive control apparatus including a voter-comparator-switch (VCS) is provided for each computer to receive signals from each of the computers and permits adaptive voting among the computers to permit the fail-operational, fail-safe operation.

  13. 30 CFR 77.902-1 - Fail safe ground check circuits; maximum voltage.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Fail safe ground check circuits; maximum voltage. 77.902-1 Section 77.902-1 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF... ground check circuits; maximum voltage. The maximum voltage used for ground check circuits under § 77.902...

  14. 30 CFR 77.902-1 - Fail safe ground check circuits; maximum voltage.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Fail safe ground check circuits; maximum voltage. 77.902-1 Section 77.902-1 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF... ground check circuits; maximum voltage. The maximum voltage used for ground check circuits under § 77.902...

  15. Fail-Safe Magnetic Bearing Controller Demonstrated Successfully

    NASA Technical Reports Server (NTRS)

    Choi, Benjamin B.; Provenza, Andrew J.

    2001-01-01

    The Structural Mechanics and Dynamics Branch has successfully demonstrated a fail-safe controller for the Fault-Tolerant Magnetic Bearing rig at the NASA Glenn Research Center. The rotor is supported by two 8-pole redundant radial bearings, and coil failing situations are simulated by manually shutting down their control current commands from the controller cockpit. The effectiveness of the controller was demonstrated when only two active coils from each radial bearing could be used (that is, 14 coils failed). These remaining two coils still levitated the rotor and spun it without losing stability or desired position up to the maximum allowable speed of 20,000 rpm.

  16. 75 FR 77524 - Special Conditions: Sikorsky Aircraft Corporation Model S-92A Helicopter; Installation of a...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-13

    ... must provide fail-safe operations during coupled maneuvers. The demonstration of fail-safe operations... receive your comments by February 11, 2011. ADDRESSES: You must mail or deliver two copies of your... your comments: Docket No. SW023. You can inspect comments in the Docket on weekdays, except Federal...

  17. Modelling operations and security of cloud systems using Z-notation and Chinese Wall security policy

    NASA Astrophysics Data System (ADS)

    Basu, Srijita; Sengupta, Anirban; Mazumdar, Chandan

    2016-11-01

    Enterprises are increasingly using cloud computing for hosting their applications. Availability of fast Internet and cheap bandwidth are causing greater number of people to use cloud-based services. This has the advantage of lower cost and minimum maintenance. However, ensuring security of user data and proper management of cloud infrastructure remain major areas of concern. Existing techniques are either too complex, or fail to properly represent the actual cloud scenario. This article presents a formal cloud model using the constructs of Z-notation. Principles of the Chinese Wall security policy have been applied to design secure cloud-specific operations. The proposed methodology will enable users to safely host their services, as well as process sensitive data, on cloud.

  18. A Statistical Simulation Approach to Safe Life Fatigue Analysis of Redundant Metallic Components

    NASA Technical Reports Server (NTRS)

    Matthews, William T.; Neal, Donald M.

    1997-01-01

    This paper introduces a dual active load path fail-safe fatigue design concept analyzed by Monte Carlo simulation. The concept utilizes the inherent fatigue life differences between selected pairs of components for an active dual path system, enhanced by a stress level bias in one component. The design is applied to a baseline design; a safe life fatigue problem studied in an American Helicopter Society (AHS) round robin. The dual active path design is compared with a two-element standby fail-safe system and the baseline design for life at specified reliability levels and weight. The sensitivity of life estimates for both the baseline and fail-safe designs was examined by considering normal and Weibull distribution laws and coefficient of variation levels. Results showed that the biased dual path system lifetimes, for both the first element failure and residual life, were much greater than for standby systems. The sensitivity of the residual life-weight relationship was not excessive at reliability levels up to R = 0.9999 and the weight penalty was small. The sensitivity of life estimates increases dramatically at higher reliability levels.

  19. From Barrier Free to Safe Environments: The New Zealand Experience. Monograph #44.

    ERIC Educational Resources Information Center

    Wrightson, William; Pope, Campbell

    Intrinsically safe design is presented as a logical extension of the principles of barrier free design, and as a higher level design strategy for effecting widespread implementation of the basic accessibility requirements for people with disabilities. Two fundamental planning procedures are proposed: including principles of safe and accessible…

  20. A fully integrated new paradigm for lithium's mode of action - lithium utilizes latent cellular fail-safe mechanisms.

    PubMed

    van Woerkom, Arthur Ernst

    2017-01-01

    It is proposed that lithium's therapeutic effects occur indirectly by augmenting a cascade of protective "fail-safe" pathways pre-configured to activate in response to a dangerous low cell [Mg ++ ] situation, eg, posttraumatic brain injury, alongside relative cell adenosine triphosphate depletion. Lithium activates cell protection, as it neatly mimics a lowered intracellular [Mg ++ ] level.

  1. A fail safe laser activated switch used as an emergency control link at the Langley Vortex Research Facility

    NASA Technical Reports Server (NTRS)

    Kassel, P. C., Jr.

    1978-01-01

    A fail safe light activated switch was used as an emergency control link at the Langley Vortex Research Facility. In this facility aircraft models were towed through a still air test chamber by a gasoline powered vehicle which was launched from one end of a 427-meter track and attained velocities to 31 m/sec in the test chamber. A 5 mW HeNe laser with a mechanical copper provided a connecting link with the moving tow vehicle on which a silicon photodiode receiver with a specially designed amplifier provided a fail safe switching action. This system provided an emergency means of stopping the vehicle by turning off the laser to interrupt the power to the vehicle ignition and brake release systems.

  2. Towards a damage tolerance philosophy for composite materials and structures

    NASA Technical Reports Server (NTRS)

    O'Brien, T. Kevin

    1990-01-01

    A damage-threshold/fail-safe approach is proposed to ensure that composite structures are both sufficiently durable for economy of operation, as well as adequately fail-safe or damage tolerant for flight safety. Matrix cracks are assumed to exist throughout the off-axis plies. Delamination onset is predicted using a strain energy release rate characterization. Delamination growth is accounted for in one of three ways: either analytically, using delamination growth laws in conjunction with strain energy release rate analyses incorporating delamination resistance curves; experimentally, using measured stiffness loss; or conservatively, assuming delamination onset corresponds to catastrophic delamination growth. Fail-safety is assessed by accounting for the accumulation of delaminations through the thickness. A tension fatigue life prediction for composite laminates is presented as a case study to illustrate how this approach may be implemented. Suggestions are made for applying the damage-threshold/fail-safe approach to compression fatigue, tension/compression fatigue, and compression strength following low velocity impact.

  3. Towards a damage tolerance philosophy for composite materials and structures

    NASA Technical Reports Server (NTRS)

    Obrien, T. Kevin

    1988-01-01

    A damage-threshold/fail-safe approach is proposed to ensure that composite structures are both sufficiently durable for economy of operation, as well as adequately fail-safe or damage tolerant for flight safety. Matrix cracks are assumed to exist throughout the off-axis plies. Delamination onset is predicted using a strain energy release rate characterization. Delamination growth is accounted for in one of three ways: either analytically, using delamination growth laws in conjunction with strain energy release rate analyses incorporating delamination resistance curves; experimentally, using measured stiffness loss; or conservatively, assuming delamination onset corresponds to catastrophic delamination growth. Fail-safety is assessed by accounting for the accumulation of delaminations through the thickness. A tension fatigue life prediction for composite laminates is presented as a case study to illustrate how this approach may be implemented. Suggestions are made for applying the damage-threshold/fail-safe approach to compression fatigue, tension/compression fatigue, and compression strength following low velocity impact.

  4. Solutions for Failing High Schools: Converging Visions and Promising Models.

    ERIC Educational Resources Information Center

    Legters, Nettie; Balfanz, Robert; McPartland, James

    Promising solutions to the failings of traditional comprehensive high schools were reviewed to identify basic principles and strategies for improving high schools nationwide. Selected research studies, policy documents, and promising high school programs were reviewed. The review revealed the following principles for helping high schools better…

  5. Fail-safe designs for large capacity battery systems

    DOEpatents

    Kim, Gi-Heon; Smith, Kandler; Ireland, John; Pesaran, Ahmad A.; Neubauer, Jeremy

    2016-05-17

    Fail-safe systems and design methodologies for large capacity battery systems are disclosed. The disclosed systems and methodologies serve to locate a faulty cell in a large capacity battery, such as a cell having an internal short circuit, determine whether the fault is evolving, and electrically isolate the faulty cell from the rest of the battery, preventing further electrical energy from feeding into the fault.

  6. Violations of the ceiling principle: exact conditions and statistical evidence.

    PubMed Central

    Slimowitz, J R; Cohen, J E

    1993-01-01

    The National Research Council recommended the use of the ceiling principle in forensic applications of DNA testing on the grounds that the ceiling principle was believed to be "conservative," giving estimates greater than or equal to the actual genotype frequencies in the appropriate reference population. We show here that the ceiling principle can fail to be conservative in a population with two subpopulations and two loci, each with two alleles at Hardy-Weinberg equilibrium, if there is some linkage disequilibrium between loci. We also show that the ceiling principle can fail in a population with two subpopulations and a single locus with two alleles if Hardy-Weinberg equilibrium does not hold. We give explicit analytical formulas to describe when the ceiling principle fails. By showing that the ceiling principle is not always mathematically reliable, this analysis gives users of the ceiling principle the responsibility of demonstrating that it is conservative for the particular data with which it is used. Our reanalysis of VNTR data bases of the FBI provides compelling evidence of two-locus associations within three major ethnic groups (Caucasian, black, and Hispanic) in the United States, even though the loci tested are located on different chromosomes. Before the ceiling principle is implemented, more research should be done to determine whether it may be violated in practice. PMID:8328450

  7. Need for Robust Sensors for Inherently Fail-Safe Gas Turbine Engine Controls, Monitoring, and Prognostics (Postprint)

    DTIC Science & Technology

    2006-09-01

    MONITORING , AND PROGNOSTICS Alireza R. Behbahani Controls / Engine Health Management Turbine Engine Division / PRTS U.S. Air Force Research...Technical Report 2005. 8. Greitzer, Frank et al, “Gas Turbine Engine Health Monitoring and Prognostics ”, International Society of Logistics (SOLE...AFRL-PR-WP-TP-2007-217 NEED FOR ROBUST SENSORS FOR INHERENTLY FAIL-SAFE GAS TURBINE ENGINE CONTROLS, MONITORING , AND PROGNOSTICS (POSTPRINT

  8. Peroral endoscopic myotomy is a viable option for failed surgical esophagocardiomyotomy instead of redo surgical Heller myotomy: a single center prospective study.

    PubMed

    Onimaru, Manabu; Inoue, Haruhiro; Ikeda, Haruo; Yoshida, Akira; Santi, Esperanza Grace; Sato, Hiroki; Ito, Hiroaki; Maselli, Roberta; Kudo, Shin-ei

    2013-10-01

    Surgical Heller myotomy has high rates of successful long-term results, but failed cases still remain. Moreover, the treatment strategy in patients with surgical myotomy failure is controversial. Recently, peroral endscopic myotomy (POEM) was reported to be efficient and safe in primary treatment of achalasia. In this study, we aimed to evaluate the efficacy and safety of POEM for surgical myotomy failure as a rescue second-line treatment, and we discuss the treatment options adapted in achalasia recurrence. A total of 315 consecutive achalasia patients received POEM from September 2008 to December 2012 in our hospital. Eleven (3.5%) patients who had persistent or recurrent achalasia and had received surgical myotomy as a first-line treatment from other hospitals were included in this study. Patient background, barium swallow studies, esophagogastroduodenoscopy (EGD), manometry, and symptom scores were prospectively evaluated. In principle, all patients in whom surgical myotomy failed received pneumatic balloon dilatation (PBD) as the first line "rescue" treatment, and only if PBD failed were patients considered for rescue POEM. The PBD alone was effective in 1 patient, and in the remaining 10 patients, rescue POEM was performed successfully without complications. Three months after rescue POEM, significant reduction in lower esophageal sphincter (LES) resting pressures (22.1 ± 6.6 mmHg vs 10.9 ± 4.5 mmHg, p < 0.01) and Eckardt symptom scores (6.5 ± 1.3 vs 1.1 ± 1.3, p < 0.001) were observed. Short-term results of POEM for failed surgical myotomy were excellent. Long-term results are awaited. Copyright © 2013 American College of Surgeons. Published by Elsevier Inc. All rights reserved.

  9. Turbine vane segment and impingement insert configuration for fail-safe impingement insert retention

    DOEpatents

    Burdgick, Steven Sebastian; Kellock, Iain Robertson

    2003-05-13

    An impingement insert sleeve is provided that is adapted to be disposed in a coolant cavity defined through a stator vane. The insert has a generally open inlet end and first and second pairs of diametrically opposed side walls, and at least one fail-safe tab defined at a longitudinal end of the insert for limiting radial displacement of the insert with respect to the stator vane.

  10. Publication Bias in Meta-Analysis: Confidence Intervals for Rosenthal's Fail-Safe Number.

    PubMed

    Fragkos, Konstantinos C; Tsagris, Michail; Frangos, Christos C

    2014-01-01

    The purpose of the present paper is to assess the efficacy of confidence intervals for Rosenthal's fail-safe number. Although Rosenthal's estimator is highly used by researchers, its statistical properties are largely unexplored. First of all, we developed statistical theory which allowed us to produce confidence intervals for Rosenthal's fail-safe number. This was produced by discerning whether the number of studies analysed in a meta-analysis is fixed or random. Each case produces different variance estimators. For a given number of studies and a given distribution, we provided five variance estimators. Confidence intervals are examined with a normal approximation and a nonparametric bootstrap. The accuracy of the different confidence interval estimates was then tested by methods of simulation under different distributional assumptions. The half normal distribution variance estimator has the best probability coverage. Finally, we provide a table of lower confidence intervals for Rosenthal's estimator.

  11. Publication Bias in Meta-Analysis: Confidence Intervals for Rosenthal's Fail-Safe Number

    PubMed Central

    Fragkos, Konstantinos C.; Tsagris, Michail; Frangos, Christos C.

    2014-01-01

    The purpose of the present paper is to assess the efficacy of confidence intervals for Rosenthal's fail-safe number. Although Rosenthal's estimator is highly used by researchers, its statistical properties are largely unexplored. First of all, we developed statistical theory which allowed us to produce confidence intervals for Rosenthal's fail-safe number. This was produced by discerning whether the number of studies analysed in a meta-analysis is fixed or random. Each case produces different variance estimators. For a given number of studies and a given distribution, we provided five variance estimators. Confidence intervals are examined with a normal approximation and a nonparametric bootstrap. The accuracy of the different confidence interval estimates was then tested by methods of simulation under different distributional assumptions. The half normal distribution variance estimator has the best probability coverage. Finally, we provide a table of lower confidence intervals for Rosenthal's estimator. PMID:27437470

  12. Filter assembly for metallic and intermetallic tube filters

    DOEpatents

    Alvin, Mary Anne; Lippert, Thomas E.; Bruck, Gerald J.; Smeltzer, Eugene E.

    2001-01-01

    A filter assembly (60) for holding a filter element (28) within a hot gas cleanup system pressure vessel is provided, containing: a filter housing (62), said filter housing having a certain axial length and having a peripheral sidewall, said sidewall defining an interior chamber (66); a one piece, all metal, fail-safe/regenerator device (68) within the interior chamber (66) of the filter housing (62) and/or extending beyond the axial length of the filter housing, said device containing an outward extending radial flange (71) within the filter housing for seating an essential seal (70), the device also having heat transfer media (72) disposed inside and screens (80) for particulate removal; one compliant gasket (70) positioned next to and above the outward extending radial flange of the fail-safe/regenerator device; and a porous metallic corrosion resistant superalloy type filter element body welded at the bottom of the metal fail-safe/regenerator device.

  13. Fail-safe mechanism of GCN4 translational control—uORF2 promotes reinitiation by analogous mechanism to uORF1 and thus secures its key role in GCN4 expression

    PubMed Central

    Gunišová, Stanislava; Valášek, Leoš Shivaya

    2014-01-01

    One of the extensively studied mechanisms of gene-specific translational regulation is reinitiation. It takes place on messenger RNAs (mRNAs) where main ORF is preceded by upstream ORF (uORF). Even though uORFs generally down-regulate main ORF expression, specific uORFs exist that allow high level of downstream ORF expression. The key is their ability to retain 40S subunits on mRNA upon termination of their translation to resume scanning for the next AUG. Here, we took advantage of the exemplary model system of reinitiation, the mRNA of yeast transcriptional activator GCN4 containing four short uORFs, and show that contrary to previous reports, not only the first but the first two of its uORFs allow efficient reinitiation. Strikingly, we demonstrate that they utilize a similar molecular mechanism relying on several cis-acting 5′ reinitiation-promoting elements, one of which they share, and the interaction with the a/TIF32 subunit of translation initiation factor eIF3. Since a similar mechanism operates also on YAP1 uORF, our findings strongly suggest that basic principles of reinitiation are conserved. Furthermore, presence of two consecutive reinitiation-permissive uORFs followed by two reinitiation-non-permissive uORFs suggests that tightness of GCN4 translational control is ensured by a fail-safe mechanism that effectively prevents or triggers GCN4 expression under nutrient replete or deplete conditions, respectively. PMID:24623812

  14. 12 CFR 7.4002 - National bank charges.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... judgment and safe and sound banking principles. A national bank establishes non-interest charges and fees in accordance with safe and sound banking principles if the bank employs a decision-making process... of the competitive position of the bank in accordance with the bank's business plan and marketing...

  15. Spinal Injuries in the Aquatics Environment, Part I: Prevention.

    ERIC Educational Resources Information Center

    Dworkin, Gerald M.

    1987-01-01

    Water-related activities are the number one cause of spinal cord injuries resulting from sports and recreation activities. This article discusses principles of safe diving; principles of safe water sliding; ways to reduce springboard diving accidents; factors contributing to springboard diving accidents; and safety recommendations for open water…

  16. Alternative Fuels Data Center

    Science.gov Websites

    Autonomous Vehicle (AV) Safe Testing Regulations Arizona state agencies must support the testing fails, the vehicle must be brought to a complete stop or safe state. The Arizona Department of Public

  17. Ontological approach for safe and effective polypharmacy prescription

    PubMed Central

    Grando, Adela; Farrish, Susan; Boyd, Cynthia; Boxwala, Aziz

    2012-01-01

    The intake of multiple medications in patients with various medical conditions challenges the delivery of medical care. Initial empirical studies and pilot implementations seem to indicate that generic safe and effective multi-drug prescription principles could be defined and reused to reduce adverse drug events and to support compliance with medical guidelines and drug formularies. Given that ontologies are known to provide well-principled, sharable, setting-independent and machine-interpretable declarative specification frameworks for modeling and reasoning on biomedical problems, we explore here their use in the context of multi-drug prescription. We propose an ontology for modeling drug-related knowledge and a repository of safe and effective generic prescription principles. To test the usability and the level of granularity of the developed ontology-based specification models and heuristic we implemented a tool that computes the complexity of multi-drug treatments, and a decision aid to check the safeness and effectiveness of prescribed multi-drug treatments. PMID:23304299

  18. The method of 'principlism': a critique of the critique.

    PubMed

    Lustig, B A

    1992-10-01

    Several scholars have recently criticized the dominant emphasis upon mid-level principles in bioethics best exemplified by Beauchamp and Childress's Principles of Biomedical Ethics. In Part I of this essay, I assess the fairness and cogency of three broad criticisms raised against 'principlism' as an approach: (1) that principlism, as an exercise in applied ethics, is insufficiently attentive to the dialectical relations between ethical theory and mortal practice; (2) that principlism fails to offer a systematic account of the principles of non-maleficence, beneficence, respect for autonomy, and justice; and (3) that principlism, as a version of moral pluralism, is fatally flawed by its theoretical agnosticism. While acknowledging that Beauchamp and Childress's reliance upon Ross's version of intuitionism is problematic, I conclude that the critics of principlism have failed to make a compelling case against its theoretical or practical adequacy as an ethical approach. In Part II, I assess the moral theory developed by Bernard Gert in Mortality: A New Justification of the Moral Rules, because Gert has recommended his approach as a systematic alternative to principlism. I judge Gert's theory to be seriously incomplete and, in contrast to principlism, unable to generate coherent conclusions about cases of active euthanasia and paternalism.

  19. Investigation of structural factors of safety for the space shuttle

    NASA Technical Reports Server (NTRS)

    1972-01-01

    A study was made of the factors governing the structural design of the fully reusable space shuttle booster to establish a rational approach to select optimum structural factors of safety. The study included trade studies of structural factors of safety versus booster service life, weight, cost, and reliability. Similar trade studies can be made on other vehicles using the procedures developed. The major structural components of a selected baseline booster were studied in depth, each being examined to determine the fatigue life, safe-life, and fail-safe capabilities of the baseline design. Each component was further examined to determine its reliability and safety requirements, and the change of structural weight with factors of safety. The apparent factors of safety resulting from fatigue, safe-life, proof test, and fail-safe requirements were identified. The feasibility of reduced factors of safety for design loads such as engine thrust, which are well defined, was examined.

  20. Critical issues in assuring long lifetime and fail-safe operation of optical communications network

    NASA Astrophysics Data System (ADS)

    Paul, Dilip K.

    1993-09-01

    Major factors in assuring long lifetime and fail-safe operation in optical communications networks are reviewed in this paper. Reliable functionality to design specifications, complexity of implementation, and cost are the most critical issues. As economics is the driving force to set the goals as well as priorities for the design, development, safe operation, and maintenance schedules of reliable networks, a balance is sought between the degree of reliability enhancement, cost, and acceptable outage of services. Protecting both the link and the network with high reliability components, hardware duplication, and diversity routing can ensure the best network availability. Case examples include both fiber optic and lasercom systems. Also, the state-of-the-art reliability of photonics in space environment is presented.

  1. Design of a bistable electromagnetic coupling mechanism for underactuated manipulators

    NASA Astrophysics Data System (ADS)

    Miyuranga Kaluarachchi, Malaka; Ho, Jee-Hou; Yahya, Samer; Teh, Sze-Hong

    2018-07-01

    Electromagnetic clutches have been widely used in underactuated lightweight manipulator designs as a coupling mechanism due to their advantages of fast activation and electrical controllability. However, an electromagnetic clutch consumes electrical energy continuously during its operation. Furthermore, conventional electromagnetic clutches are not fail-safe in unexpected power failure conditions. These factors have a significant impact on the energy efficiency and the safety of the design, and these are vital aspects for underactuated lightweight manipulators. This paper introduces a bistable electromagnetic coupling mechanism design, with reduced energy consumption and with a fail-safe mechanism. The concept of a bistable electromagnetic mechanism consists of an electromagnet with two permanent magnets. The design has the capability to maintain stable mechanism states, either engaged or disengaged, without a continuous electrical power supply, thus enhancing fail-safety and efficiency. Moreover, the design incorporates the advantages of conventional electromagnetic clutches such as rapid activation and electrical controllability. The experimental results highlight the effectiveness of the proposed mechanism in reducing electric energy consumption. Besides this, a theoretical model is developed and a good correlation is achieved between the theoretical and experimental results. The reduced electric energy consumption and fail-safe design make the bistable electromagnetic mechanism a promising concept for underactuated lightweight manipulators.

  2. Hyaluronic acid-green tea catechin micellar nanocomplexes: Fail-safe cisplatin nanomedicine for the treatment of ovarian cancer without off-target toxicity.

    PubMed

    Bae, Ki Hyun; Tan, Susi; Yamashita, Atsushi; Ang, Wei Xia; Gao, Shu Jun; Wang, Shu; Chung, Joo Eun; Kurisawa, Motoichi

    2017-12-01

    The green tea catechin, (-)-epigallocatechin-3-O-gallate (EGCG), has gained significant attention as a potent adjuvant to enhance the antitumor efficacy of cisplatin while mitigating its harmful side effects. Herein we report the development of a fail-safe cisplatin nanomedicine constructed with hyaluronic acid-EGCG conjugate for ovarian cancer therapy. A simple mixing of this conjugate and cisplatin induces spontaneous self-assembly of micellar nanocomplexes having a spherical core-shell structure. The surface-exposed hyaluronic acid enables efficient delivery of cisplatin into CD44-overexpressing cancer cells via receptor-mediated endocytosis whereas the internally packed EGCG moieties offer an environment favorable for the encapsulation of cisplatin. In addition, the antioxidant effect of EGCG moieties ensures fail-safe protection against off-target organ toxicity originating from cisplatin-evoked oxidative stress. Pharmacokinetic and biodistribution studies reveal the prolonged blood circulation and preferential tumor accumulation of intravenously administered nanocomplexes. Moreover, the nanocomplexes exhibit superior antitumor efficacy over free cisplatin while displaying no toxicity in both a subcutaneous xenograft model and peritoneal metastatic model of human ovarian cancer. Our findings demonstrate proof of concept for the feasibility of green tea catechin-based micellar nanocomplexes as a safe and effective cisplatin nanomedicine for ovarian cancer treatment. Copyright © 2017 Elsevier Ltd. All rights reserved.

  3. Redundant electronic circuit provides fail-safe control

    NASA Technical Reports Server (NTRS)

    Archer, J. W.

    1970-01-01

    Circuit using dual control amplifiers and dual position demand potentiometers powered from separate sources is used for reliable hydraulic valve controller that prevents closure of valve when control circuits fail, and maintains valve control to close tolerance for more common modes of controller failure.

  4. The principle of procreative beneficence: old arguments and a new challenge.

    PubMed

    Hotke, Andrew

    2014-06-01

    In the last ten years, there have been a number of attempts to refute Julian Savulescu's Principle of Procreative Beneficence; a principle which claims that parents have a moral obligation to have the best child that they can possibly have. So far, no arguments against this principle have succeeded at refuting it. This paper tries to explain the shortcomings of some of the more notable arguments against this principle. I attempt to break down the argument for the principle and in doing so, I explain what is needed to properly refute it. This helps me show how and why the arguments of Rebecca Bennett, Sarah Stoller and others fail to refute the principle. Afterwards, I offer a new challenge to the principle. I attack what I understand to be a fundamental premise of the argument, a premise which has been overlooked in the literature written about this principle. I argue that there is no reason to suppose, as Savulescu does, that morality requires us to do what we have most reason to do. If we reject this premise, as I believe we have reason to do, the argument for Procreative Beneficence fails. © 2012 John Wiley & Sons Ltd.

  5. 78 FR 20604 - Enhanced Document Requirements To Support Use of the Dolphin Safe Label on Tuna Products

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-05

    ... Commission Act for including a dolphin-safe label on tuna product in the United States that fails to meet the.... 130221153-3153-01] RIN 0648-BC78 Enhanced Document Requirements To Support Use of the Dolphin Safe Label on Tuna Products AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and Atmospheric...

  6. Respiratory transfer value has fail-safe feature

    NASA Technical Reports Server (NTRS)

    Puccinelli, A. A.; Smith, J. R., Jr.

    1965-01-01

    Quick-acting, remote controlled valve connects either one of two oxygen or air supplies to a breathing tube. The valve, which is fall-safe, incorporates a cammed piston arrangement that is driven by a remote controlled reversible rotary solenoid or reversible electric motor.

  7. Improved Quick Disconnect (QD) Interface Through Fail Safe Parts Identification

    NASA Technical Reports Server (NTRS)

    Blanch-Payne, Evelyn

    2001-01-01

    An extensive review of existing Quick Disconnects (QDs) mating and demating operations was performed to determine which shuttle part interface identifications and procedures contribute to human factor errors. The research methods used consisted of interviews with engineers and technicians, examination of incident reports, critiques of video and audio tapes of QD operations, and attendance of a Hyper QD operational course. The data strongly suggests that there are inherit human factor errors involved in QD operations. To promote fail-safe operations, QD interface problem areas and recommendations were outlined and reviewed. It is suggested that dialogue, investigations and recommendations continue.

  8. Fail-safe storage rack for irradiated fuel rod assemblies

    DOEpatents

    Lewis, D.R.

    1993-03-23

    A fail-safe storage rack is provided for interim storage of spent but radioactive nuclear fuel rod assemblies. The rack consists of a checkerboard array of substantially square, elongate receiving tubes fully enclosed by a double walled container, the outer wall of which is imperforate for liquid containment and the inner wall of which is provided with perforations for admitting moderator liquid flow to the elongate receiving tubes, the liquid serving to take up waste heat from the stored nuclear assemblies and dissipate same to the ambient liquid reservoir. A perforated cover sealing the rack facilitates cooling liquid entry and dissipation.

  9. Fail-safe storage rack for irradiated fuel rod assemblies

    DOEpatents

    Lewis, Donald R.

    1993-01-01

    A fail-safe storage rack is provided for interim storage of spent but radioactive nuclear fuel rod assemblies. The rack consists of a checkerboard array of substantially square, elongate receiving tubes fully enclosed by a double walled container, the outer wall of which is imperforate for liquid containment and the inner wall of which is provided with perforations for admitting moderator liquid flow to the elongate receiving tubes, the liquid serving to take up waste heat from the stored nuclear assemblies and dissipate same to the ambient liquid reservoir. A perforated cover sealing the rack facilitates cooling liquid entry and dissipation.

  10. Fail-safe transcription termination: Because one is never enough.

    PubMed

    Lemay, Jean-François; Bachand, François

    2015-01-01

    Termination of RNA polymerase II (RNAPII) transcription is a fundamental step of gene expression that involves the release of the nascent transcript and dissociation of RNAPII from the DNA template. As transcription termination is intimately linked to RNA 3' end processing, termination pathways have a key decisive influence on the fate of the transcribed RNA. Quite remarkably, when reaching the 3' end of genes, a substantial fraction of RNAPII fail to terminate transcription, requiring the contribution of alternative or "fail-safe" mechanisms of termination to release the polymerase. This point of view covers redundant mechanisms of transcription termination and how they relate to conventional termination models. In particular, we expand on recent findings that propose a reverse torpedo model of termination, in which the 3'5' exonucleolytic activity of the RNA exosome targets transcription events associated with paused and backtracked RNAPII.

  11. On the Safety of Machine Learning: Cyber-Physical Systems, Decision Sciences, and Data Products.

    PubMed

    Varshney, Kush R; Alemzadeh, Homa

    2017-09-01

    Machine learning algorithms increasingly influence our decisions and interact with us in all parts of our daily lives. Therefore, just as we consider the safety of power plants, highways, and a variety of other engineered socio-technical systems, we must also take into account the safety of systems involving machine learning. Heretofore, the definition of safety has not been formalized in a machine learning context. In this article, we do so by defining machine learning safety in terms of risk, epistemic uncertainty, and the harm incurred by unwanted outcomes. We then use this definition to examine safety in all sorts of applications in cyber-physical systems, decision sciences, and data products. We find that the foundational principle of modern statistical machine learning, empirical risk minimization, is not always a sufficient objective. We discuss how four different categories of strategies for achieving safety in engineering, including inherently safe design, safety reserves, safe fail, and procedural safeguards can be mapped to a machine learning context. We then discuss example techniques that can be adopted in each category, such as considering interpretability and causality of predictive models, objective functions beyond expected prediction accuracy, human involvement for labeling difficult or rare examples, and user experience design of software and open data.

  12. 75 FR 26883 - Airworthiness Directives; Empresa Brasileira de Aeronautica S.A. (EMBRAER) Model ERJ 170 and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-13

    ... slat actuator structural failure (rupture) and its adjacent actuator torque limiter failing high... outboard slat actuator structural failure (rupture) and its adjacent actuator torque limiter failing high... requirements.'' Under that section, Congress charges the FAA with promoting safe flight of civil aircraft in...

  13. What's Wrong With Conservation Education?

    ERIC Educational Resources Information Center

    Hobart, Willis L.

    1972-01-01

    Conservation and conservation education are critically examined, their definitions, foundations, principles, concepts, weaknesses, failures, and successes. It is concluded educators must first educate themselves, or environmental education will fail the same way conservation education has failed to educate Americans to the intricate…

  14. 77 FR 24362 - Airworthiness Directives; Bombardier, Inc. Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-24

    ... was prompted by reports of the air driven generator (ADG) failing to power essential buses during... essential buses which, in the event of an emergency, could prevent continued safe flight. DATES: This AD... prevent continued safe flight. This [TCCA] directive mandates the replacement of the ADG GCU. You may...

  15. Modified hydraulic braking system limits angular deceleration to safe values

    NASA Technical Reports Server (NTRS)

    Briggs, R. S.; Council, M.; Green, P. M.

    1966-01-01

    Conventional spring actuated, hydraulically released, fail-safe disk braking system is modified to control the angular deceleration of a massive antenna. The hydraulic system provides an immediate preset pressure to the spring-loaded brake shoes and holds it at this value to decelerate the antenna at the desired rate.

  16. Braking System for Wind Turbines

    NASA Technical Reports Server (NTRS)

    Krysiak, J. E.; Webb, F. E.

    1987-01-01

    Operating turbine stopped smoothly by fail-safe mechanism. Windturbine braking systems improved by system consisting of two large steel-alloy disks mounted on high-speed shaft of gear box, and brakepad assembly mounted on bracket fastened to top of gear box. Lever arms (with brake pads) actuated by spring-powered, pneumatic cylinders connected to these arms. Springs give specific spring-loading constant and exert predetermined load onto brake pads through lever arms. Pneumatic cylinders actuated positively to compress springs and disengage brake pads from disks. During power failure, brakes automatically lock onto disks, producing highly reliable, fail-safe stops. System doubles as stopping brake and "parking" brake.

  17. Reciprocity-Based Reasons for Benefiting Research Participants: Most Fail, the Most Plausible is Problematic

    PubMed Central

    Sofaer, Neema

    2014-01-01

    A common reason for giving research participants post-trial access (PTA) to the trial intervention appeals to reciprocity, the principle, stated most generally, that if one person benefits a second, the second should reciprocate: benefit the first in return. Many authors consider it obvious that reciprocity supports PTA. Yet their reciprocity principles differ, with many authors apparently unaware of alternative versions. This article is the first to gather the range of reciprocity principles. It finds that: (1) most are false. (2) The most plausible principle, which is also problematic, applies only when participants experience significant net risks or burdens. (3) Seldom does reciprocity support PTA for participants or give researchers stronger reason to benefit participants than equally needy non-participants. (4) Reciprocity fails to explain the common view that it is bad when participants in a successful trial have benefited from the trial intervention but lack PTA to it. PMID:24602060

  18. 75 FR 79921 - Fall 2010 Unified Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-20

    ... securitizations that would be affected by recent changes to generally accepted accounting principles. In effect... generally accepted accounting principles in effect prior to November 15, 2009. The transitional safe harbor... conditions for sale accounting treatment under generally accepted accounting principles as [[Page 79923...

  19. Establishment of design criteria for acceptable failure modes and fail safe considerations for the space shuttle structural system

    NASA Technical Reports Server (NTRS)

    Westrup, R. W.

    1972-01-01

    Investigations of fatigue life, and safe-life and fail-safe design concepts as applied to space shuttle structure are summarized. The results are evaluated to select recommended structural design criteria to provide assurance that premature failure due to propagation of undetected crack-like defects will not occur during shuttle operational service. The space shuttle booster, GDC configuration B-9U, is selected as the reference vehicle. Structural elements used as basis of detail analyses include wing spar caps, vertical stabilizer skins, crew compartment skin, orbiter support frame, and propellant tank shell structure. Fatigue life analyses of structural elements are performed to define potential problem areas and establish upper limits of operating stresses. Flaw growth analyses are summarized in parametric form over a range of initial flaw types and sizes, operating stresses and service life requirements. Service life of 100 to 500 missions is considered.

  20. When the science fails and the ethics works: 'Fail-safe' ethics in the FEM-PrEP study.

    PubMed

    Kingori, Patricia

    2015-12-01

    This paper will explore the concept of 'fail safe' ethics in the FEM PrEP trial, and the practice of research and ethics on the ground. FEM-PrEP examined the efficacy of PrEP in African women after promising outcomes in research conducted with MSM. This was a hugely optimistic time and FEM-PrEP was mobilised using rights-based ethical arguments that women should have access to PrEP. This paper will present data collected during an ethnographic study of frontline research workers involved in FEM-PrEP. During our discussions, 'fail-safe' ethics emerged as concept that encapsulated their confidence that their ethics could not fail. However, in 2011, FEM-PrEP was halted and deemed a failure. The women involved in the study were held responsible because contrary to researcher's expectations they were not taking the oral PrEP being researched. This examination of FEM-PrEP will show that ethical arguments are increasingly deployed to mobilise, maintain and in some cases stop trials in ways which, at times, are superseded or co-opted by other interests. While promoting the interests of women, rights-based approaches are argued to indirectly justify the continuation of individualised, biomedical interventions which have been problematic in other women-centred trials. In this examination of FEM-PrEP, the rights-based approach obscured: ethical concerns beyond access to PrEP; the complexities of power relationships between donor and host countries; the operations of the HIV industry in research-saturated areas and the cumulative effect of unfilled expectations in HIV research and how this has shaped ideas of research and ethics.

  1. 24 CFR 1000.2 - What are the guiding principles in the implementation of NAHASDA?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... for their own economic condition. (5) Providing affordable homes in safe and healthy environments is... safe and healthy environments on Indian reservations, in Indian communities, and in Native Alaskan... Nation: (i) By using Federal resources to aid families and individuals seeking affordable homes in safe...

  2. 75 FR 21528 - Airworthiness Directives; McDonnell Douglas Corporation Model MD-90-30 Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-26

    ... subsequently damage the hydraulic system and adversely affect the airplane's ability to make a safe landing... cylinder support fitting for the MLG failing during gear extension and subsequently damaging the hydraulic... the retract cylinder support fitting for the MLG, which could adversely affect the airplane's safe...

  3. 77 FR 8879 - Agency Information Collection Activities; Proposed Collection; Comment Request: Guidance for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-15

    ... Separator Device Operating by Centrifugal or Filtration Separation Principle AGENCY: Food and Drug... automated blood cell separator device operating by centrifugal or filtration separation principle. DATES... Filtration Separation Principle (OMB Control Number 0910-0594)--Extension Under the Safe Medical Devices Act...

  4. 5 CFR 551.202 - General principles.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false General principles. 551.202 Section 551.202 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PAY... preclude exemption under another category. For example, an engineering technician who fails to meet the...

  5. 5 CFR 551.202 - General principles.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false General principles. 551.202 Section 551.202 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PAY... preclude exemption under another category. For example, an engineering technician who fails to meet the...

  6. 5 CFR 551.202 - General principles.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 1 2012-01-01 2012-01-01 false General principles. 551.202 Section 551.202 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PAY... preclude exemption under another category. For example, an engineering technician who fails to meet the...

  7. 5 CFR 551.202 - General principles.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false General principles. 551.202 Section 551.202 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PAY... preclude exemption under another category. For example, an engineering technician who fails to meet the...

  8. Software design and implementation concepts for an interoperable medical communication framework.

    PubMed

    Besting, Andreas; Bürger, Sebastian; Kasparick, Martin; Strathen, Benjamin; Portheine, Frank

    2018-02-23

    The new IEEE 11073 service-oriented device connectivity (SDC) standard proposals for networked point-of-care and surgical devices constitutes the basis for improved interoperability due to its independence of vendors. To accelerate the distribution of the standard a reference implementation is indispensable. However, the implementation of such a framework has to overcome several non-trivial challenges. First, the high level of complexity of the underlying standard must be reflected in the software design. An efficient implementation has to consider the limited resources of the underlying hardware. Moreover, the frameworks purpose of realizing a distributed system demands a high degree of reliability of the framework itself and its internal mechanisms. Additionally, a framework must provide an easy-to-use and fail-safe application programming interface (API). In this work, we address these challenges by discussing suitable software engineering principles and practical coding guidelines. A descriptive model is developed that identifies key strategies. General feasibility is shown by outlining environments in which our implementation has been utilized.

  9. Failing to protect humanitarian workers: lessons from Britain and Voluntary Aid Detachments in the Second World War.

    PubMed

    Verma, Amol A

    2017-09-01

    This paper draws on official records of international and British organizations, newspaper reports, and volunteer memoirs to study the failure to protect humanitarian workers in the Second World War. The Second World War saw a significant expansion in the use of air warfare and flying missiles and these technological advances posed a grave threat to civilians and humanitarian workers. In this context, the International Committee of the Red Cross advocated unsuccessfully to restrict air warfare and create safe hospital zones. The British Government grappled with the tension between military and humanitarian objectives in setting its bombardment policy. Ultimately, humanitarian principles were neglected in pursuit of strategic aims, which endangered civilians and left humanitarian workers particularly vulnerable. British Voluntary Aid Detachment nurses experienced more than six-fold greater fatality rates than civil defence workers and the general population. The lessons from failures to protect humanitarian workers in the face of evolutions in warfare remain profoundly relevant.

  10. Setting the Clock for Fail-Safe Early Embryogenesis.

    PubMed

    Fickentscher, Rolf; Struntz, Philipp; Weiss, Matthias

    2016-10-28

    The embryogenesis of the small nematode Caenorhabditis elegans is a remarkably robust self-organization phenomenon. Cell migration trajectories in the early embryo, for example, are well explained by mechanical cues that push cells into positions where they experience the least repulsive forces. Yet, how this mechanically guided progress in development is properly timed has remained elusive so far. Here, we show that cell volumes and division times are strongly anticorrelated during the early embryogenesis of C. elegans with significant differences between somatic cells and precursors of the germline. Our experimental findings are explained by a simple model that in conjunction with mechanical guidance can account for the fail-safe early embryogenesis of C. elegans.

  11. 75 FR 12962 - Transitional Safe Harbor Protection for Treatment by the Federal Deposit Insurance Corporation as...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-18

    ... be affected by recent changes to generally accepted accounting principles. In effect, the Final Rule... complied with the preexisting requirements under generally accepted accounting principles in effect prior... accounting principles (``GAAP''). The rule was a clarification, rather than a limitation, of the repudiation...

  12. Evaluation of Professional Ethics Principles by Candidate Teachers

    ERIC Educational Resources Information Center

    Sahan, Gülsün

    2018-01-01

    The aim of this study is to evaluate the teaching ethics principles according to the opinions of the prospective teachers. From the teaching profession ethics principles of the students, the positive and negative aspects of professionalism, service, responsibility, justice, equality, ensuring a healthy and safe environment, morality, honesty,…

  13. 76 FR 33409 - Guidance on Deposit-Related Consumer Credit Products

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-08

    ... OCC's application of principles of safe and sound banking practices in connection with deposit-related... guidance details the principles that the OCC expects national banks to follow in connection with any... without dictating specific product terms. The OCC expects national banks to apply the principles set forth...

  14. 12 CFR 238.8 - Safe and sound operations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 4 2013-01-01 2013-01-01 false Safe and sound operations. 238.8 Section 238.8... (CONTINUED) SAVINGS AND LOAN HOLDING COMPANIES (REGULATION LL) General Provisions § 238.8 Safe and sound... inconsistent with sound banking principles or the purposes of HOLA or the Financial Institutions Supervisory...

  15. 12 CFR 238.8 - Safe and sound operations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 4 2014-01-01 2014-01-01 false Safe and sound operations. 238.8 Section 238.8... (CONTINUED) SAVINGS AND LOAN HOLDING COMPANIES (REGULATION LL) General Provisions § 238.8 Safe and sound... inconsistent with sound banking principles or the purposes of HOLA or the Financial Institutions Supervisory...

  16. 12 CFR 238.8 - Safe and sound operations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 4 2012-01-01 2012-01-01 false Safe and sound operations. 238.8 Section 238.8... (CONTINUED) SAVINGS AND LOAN HOLDING COMPANIES (REGULATION LL) General Provisions § 238.8 Safe and sound... inconsistent with sound banking principles or the purposes of HOLA or the Financial Institutions Supervisory...

  17. Compendium of fracture mechanics problems

    NASA Technical Reports Server (NTRS)

    Stallworth, R.; Wilson, C.; Meyers, C.

    1990-01-01

    Fracture mechanics analysis results are presented from the following structures/components analyzed at Marshall Space Flight Center (MSFC) between 1982 and 1989: space shuttle main engine (SSME), Hubble Space Telescope (HST), external tank attach ring, B-1 stand LOX inner tank, and solid rocket booster (SRB). Results from the SSME high pressure fuel turbopump (HPFTP) second stage blade parametric analysis determine a critical flaw size for a wide variety of stress intensity values. The engine 0212 failure analysis was a time dependent fracture life assessment. Results indicated that the disk ruptured due to an overspeed condition. Results also indicated that very small flaws in the curvic coupling area could propagate and lead to failure under normal operating conditions. It was strongly recommended that a nondestructive evaluation inspection schedule be implemented. The main ring of the HST, scheduled to launch in 1990, was analyzed by safe-life and fail-safe analyses. First safe-life inspection criteria curves for the ring inner and outer skins and the fore and aft channels were derived. Afterwards the skins and channels were determined to be fail-safe by analysis. A conservative safe-life analysis was done on the 270 redesign external tank attach ring. Results from the analysis were used to determine the nondestructive evaluation technique required.

  18. 77 FR 61027 - Notice of Lodging of Proposed Consent Decree Under the Clean Water Act and Safe Drinking Water Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-05

    ... Decree resolves alleged violations of the Clean Water Act and Safe Drinking Water Act at mobile home... provide drinking water at a number of its mobile home parks and illegally discharged sewage, failed to... environmental audits at each mobile home park, implementing corrective measures, conducting regular inspections...

  19. [Precautionary principle. State of the situation in Argentina].

    PubMed

    Kemelmajer de Carlucci, Aída

    2017-10-13

    The new Argentine Civil and Commercial Code includes the prevention principle. The precautionary Principle is regulated by the Environmental Protection Act.A significant number of cases have reached the Supreme Court of the Nation. This Court, in general, estimates that the decisions concerning the precautionary principle have definitive nature, i.e., are not merely provisional. Usually, the situation is caused by the State itself, which fails to control. The different decisions show a Judiciary worried about protecting the environment.

  20. Reciprocity-based reasons for benefiting research participants: most fail, the most plausible is problematic.

    PubMed

    Sofaer, Neema

    2014-11-01

    A common reason for giving research participants post-trial access (PTA) to the trial intervention appeals to reciprocity, the principle, stated most generally, that if one person benefits a second, the second should reciprocate: benefit the first in return. Many authors consider it obvious that reciprocity supports PTA. Yet their reciprocity principles differ, with many authors apparently unaware of alternative versions. This article is the first to gather the range of reciprocity principles. It finds that: (1) most are false. (2) The most plausible principle, which is also problematic, applies only when participants experience significant net risks or burdens. (3) Seldom does reciprocity support PTA for participants or give researchers stronger reason to benefit participants than equally needy non-participants. (4) Reciprocity fails to explain the common view that it is bad when participants in a successful trial have benefited from the trial intervention but lack PTA to it. © 2013 John Wiley & Sons Ltd.

  1. The case for fire safe cigarettes made through industry documents

    PubMed Central

    Gunja, M; Wayne, G; Landman, A; Connolly, G; McGuire, A

    2002-01-01

    Objectives: To examine the extensive research undertaken by the tobacco industry over the past 25 years toward development of a fire safe cigarette. Methods: Research was conducted through a web based search of internal tobacco industry documents made publicly available through the 1998 Master Settlement Agreement. Results: The documents reveal that the tobacco industry produced a fire safe cigarette years ago, but failed to put it on the market. These findings contradict public industry claims that denied the technical feasibility and commercial acceptability of fire safe cigarettes. Internal documents also reveal a decades long, coordinated political strategy used to block proposed legislation and obfuscate the fire safe issue. Conclusions: Federal legislation mandating fire safe cigarettes is needed. PMID:12432160

  2. 78 FR 48696 - Draft Revisions to the Marine Safety Manual, Volume III, Chapters 20-26

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-09

    ...) Updated provisions for vessel manning, including guidance for the issuing of safe manning documents; (2... Distress and Safety System (GMDSS), and the Principles of Minimum Safe Manning (IMO Resolution A.1047(27...

  3. Promising practices in the prevention of intimate partner violence among adolescents.

    PubMed

    De Grace, Alyssa; Clarke, Angela

    2012-01-01

    To inform practitioners and researchers interested in the prevention of intimate partner violence (IPV) among adolescents, 9 principles of effective prevention programs (Nation et al., 2003) were described and examples of how these principles have been incorporated into existing teen dating violence prevention programs were provided. An investigation of current prevention practices for adolescent IPV resulted in one noteworthy program that has successfully incorporated all 9 principles of effective prevention programming-Safe Dates (Substance Abuse and Mental Health Services Administration, National Registry of Evidence-based Programs and Practices [SAMHSA-NREPP], 2006). Although Safe Dates serves as a model teen dating violence prevention program, it may not be equally effective across contexts and diverse groups. Therefore, as researchers and practitioners continue to develop and refine programs to reduce adolescent IPV, the principles of effective prevention programs should serve as a guiding framework.

  4. Method and apparatus for in-cell vacuuming of radiologically contaminated materials

    DOEpatents

    Spadaro, Peter R.; Smith, Jay E.; Speer, Elmer L.; Cecconi, Arnold L.

    1987-01-01

    A vacuum air flow operated cyclone separator arrangement for collecting, handling and packaging loose contaminated material in accordance with acceptable radiological and criticality control requirements. The vacuum air flow system includes a specially designed fail-safe prefilter installed upstream of the vacuum air flow power supply. The fail-safe prefilter provides in-cell vacuum system flow visualization and automatically reduces or shuts off the vacuum air flow in the event of an upstream prefilter failure. The system is effective for collecting and handling highly contaminated radiological waste in the form of dust, dirt, fuel element fines, metal chips and similar loose material in accordance with radiological and criticality control requirements for disposal by means of shipment and burial.

  5. Epistemic Autonomy: A Criterion for Virtue?

    ERIC Educational Resources Information Center

    Mudd, Sasha

    2013-01-01

    Catherine Elgin proposes a novel principle for identifying epistemic virtue. Based loosely on Kant's Categorical Imperative, it identifies autonomy as our fundamental epistemic responsibility, and defines the epistemic virtues as those traits of character needed to exercise epistemic autonomy. I argue that Elgin's principle fails as a…

  6. Worcester 1 Inch Solenoid Actuated Gas Operated SCHe System Valves

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    MISKA, C.R.

    1 inch gas-operated full-port ball valves incorporate a solenoid and limit switches as integral parts of the actuator. These valves are normally open and fail safe to the open position (GOV-1*02 and 1*06 fail closed) to provide a flow path of helium gas to the MCO under helium purge and off-normal conditions when the MCO is isolated.

  7. Worcester 1 Inch Solenoid Actuated Gas Operated SCHe System Valves

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    VAN KATWIJK, C.

    1 inch Gas-operated full-port ball valves incorporate a solenoid and limit switches as integral parts of the actuator. These valves are normally open and fail safe to the open position (GOV-1*02 and 1*06 fail closed) to provide a flow path of helium gas to the MCO under helium purge and off-normal conditions when the MCO is isolated.

  8. How not to criticize the precautionary principle.

    PubMed

    Hughes, Jonathan

    2006-10-01

    The precautionary principle has its origins in debates about environmental policy, but is increasingly invoked in bioethical contexts. John Harris and Søren Holm argue that the principle should be rejected as incoherent, irrational, and representing a fundamental threat to scientific advance and technological progress. This article argues that while there are problems with standard formulations of the principle, Harris and Holm's rejection of all its forms is mistaken. In particular, they focus on strong versions of the principle and fail to recognize that weaker forms, which may escape their criticisms, are both possible and advocated in the literature.

  9. The Alpha-Proton-X-ray Spectrometer deployment mechanism: an anthropomorphic approach to sensor placement on Martian rocks and soil

    NASA Astrophysics Data System (ADS)

    Blomquist, Richard S.

    1995-05-01

    On July 4,1997, the Mars Pathfinder spacecraft lands on Mars and starts conducting technological and scientific experiments. One experiment, the Alpha-Proton-X-ray Spectrometer, uses a sensor head placed against rocks and soil to determine their composition. To guarantee proper placement, a deployment mechanism mounted on the Mars Rover aligns the sensor head to within 20 deg of the rock and soil surfaces. In carrying out its task, the mechanism mimics the action of a human hand and arm. Consisting of a flexible wrist, a parallel link arm, a brush dc motor actuator, and a revolutionary non-pyrotechnic fail-safe release device, the mechanism correctly positions the sensor head on rocks as high as 0.29 m and on targets whose surfaces are tilted as much as 45 deg from the nominal orientation of the sensor head face. The mechanism weighs less than 0.5 kg, can withstand 100 g's, and requires less than 2.8 N x m of actuation torque. The fail-safe coupler utilizes Cerrobend, a metal alloy that melts at 60 C, to fuse the actuator and the rest of the mechanism together. A film heater wrapped around the coupler melts the metal, and Negator springs drive the mechanism into its stowed position. The fail-safe actuates using 6.75 Watts for 5 minutes in the event of an actuator failure.

  10. The Alpha-Proton-X-ray Spectrometer deployment mechanism: An anthropomorphic approach to sensor placement on Martian rocks and soil

    NASA Technical Reports Server (NTRS)

    Blomquist, Richard S.

    1995-01-01

    On July 4,1997, the Mars Pathfinder spacecraft lands on Mars and starts conducting technological and scientific experiments. One experiment, the Alpha-Proton-X-ray Spectrometer, uses a sensor head placed against rocks and soil to determine their composition. To guarantee proper placement, a deployment mechanism mounted on the Mars Rover aligns the sensor head to within 20 deg of the rock and soil surfaces. In carrying out its task, the mechanism mimics the action of a human hand and arm. Consisting of a flexible wrist, a parallel link arm, a brush dc motor actuator, and a revolutionary non-pyrotechnic fail-safe release device, the mechanism correctly positions the sensor head on rocks as high as 0.29 m and on targets whose surfaces are tilted as much as 45 deg from the nominal orientation of the sensor head face. The mechanism weighs less than 0.5 kg, can withstand 100 g's, and requires less than 2.8 N x m of actuation torque. The fail-safe coupler utilizes Cerrobend, a metal alloy that melts at 60 C, to fuse the actuator and the rest of the mechanism together. A film heater wrapped around the coupler melts the metal, and Negator springs drive the mechanism into its stowed position. The fail-safe actuates using 6.75 Watts for 5 minutes in the event of an actuator failure.

  11. Safe Use of Pesticides, Guidelines. Occupational Safety and Health Series No. 38.

    ERIC Educational Resources Information Center

    International Labour Office, Geneva (Switzerland).

    This document provides guidance on the safe use of pesticides in agricultural work. General principles are given and followed by more detailed safety requirements for the various pesticide application techniques. Finally, the medical aspects of pesticides are considered. (BB)

  12. The statistical fluctuation study of quantum key distribution in means of uncertainty principle

    NASA Astrophysics Data System (ADS)

    Liu, Dunwei; An, Huiyao; Zhang, Xiaoyu; Shi, Xuemei

    2018-03-01

    Laser defects in emitting single photon, photon signal attenuation and propagation of error cause our serious headaches in practical long-distance quantum key distribution (QKD) experiment for a long time. In this paper, we study the uncertainty principle in metrology and use this tool to analyze the statistical fluctuation of the number of received single photons, the yield of single photons and quantum bit error rate (QBER). After that we calculate the error between measured value and real value of every parameter, and concern the propagation error among all the measure values. We paraphrase the Gottesman-Lo-Lutkenhaus-Preskill (GLLP) formula in consideration of those parameters and generate the QKD simulation result. In this study, with the increase in coding photon length, the safe distribution distance is longer and longer. When the coding photon's length is N = 10^{11}, the safe distribution distance can be almost 118 km. It gives a lower bound of safe transmission distance than without uncertainty principle's 127 km. So our study is in line with established theory, but we make it more realistic.

  13. Reconstruction of the gastric passage by a side-to-side gastrogastrostomy after failed vertical-banded gastroplasty: a case report

    PubMed Central

    Soll, Christopher; Müller, Markus K; Wildi, Stefan; Clavien, Pierre-Alain; Weber, Markus

    2008-01-01

    Introduction Vertical-banded gastroplasty, a technique that is commonly performed in the treatment of morbid obesity, represents a nonadjustable restrictive procedure which reduces the volume of the upper stomach by a vertical stapler line. In addition, a textile or silicone band restricts food passage through the stomach. Case presentation A 71-year-old woman presented with a severe gastric stenosis 11 years after vertical gastroplasty. We describe a side-to-side gastrogastrostomy as a safe surgical procedure to restore the physiological gastric passage after failed vertical-banded gastroplasty. Conclusion Occasionally, restrictive procedures for morbid obesity cannot be converted into an alternative bariatric procedure to maintain weight control. This report demonstrates that a side-to-side gastrogastrostomy is a feasible and safe procedure. PMID:18513454

  14. Positive Psychology and Adolescent Mental Health: False Promise or True Breakthrough?

    ERIC Educational Resources Information Center

    Kelley, Thomas M.

    2004-01-01

    The emerging field of positive psychology has pledged to improve the mental health of American adolescents. Yet, without a principle-based conceptual foundation to guide its study of optimal youth functioning, positive psychology will ultimately fail to keep its promise. This paper suggests that the principles of Mind, Thought and Consciousness…

  15. Arthrodesis of the knee with intramedullary nail fixation.

    PubMed

    Puranen, J; Kortelainen, P; Jalovaara, P

    1990-03-01

    Thirty-three patients had an arthrodesis of the knee by means of an intramedullary nail introduced through the greater trochanter. Fifteen of the procedures were done for a failed knee arthroplasty; eight had failed because of infection and seven, because of aseptic loosening. Twenty-nine of the thirty-three knees united three to four months after the first attempt at arthrodesis and three united after technical errors were corrected. One knee had a broken nail and a non-union; this was still untreated at the time of writing. Four nails broke: three in the line of fusion and one in the line of an infected supracondylar pseudarthrosis of the femur. No new infections developed after the arthrodesis. Three patients had had an infection and a chronic fistula before the arthrodesis, and the fistulae healed six, fourteen, and eighteen months postoperatively. In another patient, who had had infection and necrosis of the skin preoperatively, the wound healed in six months. All of these knees healed without an additional major operation. The functional result was satisfactory in all patients. After the arthrodesis, seventeen of the thirty-three patients needed less aid when walking, and no patient needed more aid. Fusion of the knee with a long intramedullary nail can be safe and effective, even in the presence of infection, if the revision is performed properly and certain technical principles are followed. It is especially important to establish good contact between the resected bones.

  16. A fully integrated new paradigm for lithium’s mode of action – lithium utilizes latent cellular fail-safe mechanisms

    PubMed Central

    van Woerkom, Arthur Ernst

    2017-01-01

    It is proposed that lithium’s therapeutic effects occur indirectly by augmenting a cascade of protective “fail-safe” pathways pre-configured to activate in response to a dangerous low cell [Mg++] situation, eg, posttraumatic brain injury, alongside relative cell adenosine triphosphate depletion. Lithium activates cell protection, as it neatly mimics a lowered intracellular [Mg++] level. PMID:28203080

  17. Fail-safe numerical control

    NASA Technical Reports Server (NTRS)

    Thompson, G. A.

    1970-01-01

    System provides duplicate set of control logic circuitry. Comparators insure that the same data is present in both circuits. If any discrepancy is found, the machine is automatically stopped, before damage can occur.

  18. The Safe Drinking Water Act First 180 Days

    ERIC Educational Resources Information Center

    Lehr, Jay H.

    1975-01-01

    The Safe Drinking Water Act protects our drinking and ground water resources. The Water Advisory Council interprets and implements the law. Implementation principles include high priorities for public health, cost considerations, state and local participation, environmental impact, decentralized decision making, and use of federal and state…

  19. Principles of mastitis treatment in sheep and goats.

    PubMed

    Mavrogianni, Vasia S; Menzies, Paula I; Fragkou, Ilektra A; Fthenakis, George C

    2011-03-01

    This article indicates the principles for treatment of mastitis in ewes/does and explains the reasons why treatment may occasionally fail. It presents the principles for administration of antimicrobial agents at drying off of the animals. Finally, it addresses the risk of antimicrobials present in milk when improper withdrawal periods are used and the issues around testing for inhibitors before putting the milk into in a farm's tank. Copyright © 2011 Elsevier Inc. All rights reserved.

  20. Human Resource Development in Small Business: An Application of Brethower's Performance Principles to on the Job Training

    ERIC Educational Resources Information Center

    Twyford, Devon; Alagaraja, Meera; Shuck, Brad

    2016-01-01

    Small businesses provide economic infrastructure in which communities develop and thrive and, in the United States alone, currently represent 99.7 percent of all employer firms. However, many small businesses fail to thrive past the first two years of establishment. Of the reasons small businesses fail, limited or non-existent employee training…

  1. Pelvic fracture urethral distraction defects in children managed by anterior sagittal trans anorectal approach: a facilitating and safe access.

    PubMed

    Onofre, Luciano Silveira; Leão, Jovelino Quintino de Souza; Gomes, Adriano Luis; Heinisch, Antonio Carlos; Leão, Fernanda Ghilardi; Carnevale, José

    2011-06-01

    Trauma injuries of the posterior urethra resulting from pelvic fracture in children tend to be complete ruptures, with upper dislocation of the prostate. This paper aims to show our experience in using an anterior sagittal transanorectal approach (ASTRA) in the treatment of such injuries. The medical records of 11 patients with pelvic fracture urethral distraction defects who had undergone anastomotic urethroplasty through ASTRA between 1997 and 2009 were reviewed. Ages ranged from 1 year and 6 months to 23 years (mean age 11 years). Of the 11 patients, 8 had previously undergone failed urethroplasties. In 10 patients it was possible to perform tension free urethroplasty. One patient required inferior pubectomy and separation of the corpora cavernosa. Patients' follow-up time varied from 10 months to 10 years and 9 months (mean 41 months). One patient had a urethral fistula and evolved with a urethral diverticulum successfully managed by diverticulectomy. One patient presented a urethral stenosis managed by urethral dilatation. Of the 11 patients, 9 presented functional urethral flow and are continent. Two patients had no urethral flow. One is undergoing bladder catheterization through the Mitrofanoff principle and the other one through the urethra. No patient presented fecal incontinence or rectourethral fistula. This access, which is increasingly being used to approach posterior urethral diseases, has proved to be safe and effective in the treatment of pelvic fracture urethral distraction defects. Copyright © 2011 Journal of Pediatric Urology Company. Published by Elsevier Ltd. All rights reserved.

  2. The Pentagonal Principle for Self-Oriented Classes.

    ERIC Educational Resources Information Center

    Ball, Jerald T.

    Under the pentagonal principle, a class is divided into groups of five (or six) to complete a discrete learning task, which is divided into five bits. Students take turns presenting the bits; if one fails, the group takes over. In this rotation, each student leads at least once in the session; the group verifies all steps. The instructor acts…

  3. A Reply on Behalf of the Relativist to Mark Mason's Justification of Universal Ethical Principles

    ERIC Educational Resources Information Center

    MacKenzie, Jim

    2007-01-01

    Mark Mason, in his "A Justification, After the Postmodern Turn, of Universal Ethical Principles and Educational Ideals" Educational Philosophy and Theory, 37 (2005), attempts to justify transcultural multiculturalism. In this paper I argue that he fails to refute moral relativism, and that multiculturalism as he interprets it is not morally…

  4. Reflections Catalyzed by an Assault on a Favorite Principle

    ERIC Educational Resources Information Center

    Schultz, Emeric

    2010-01-01

    This commentary disagrees with a recent submission (Cheung, D. "J. Chem. Educ. 2009, 86," 514-518) questioning the value of the Le Chtelier principle (LCP). Cheung points out that the LCP fails to predict the proper change in a small set of chemical equilibria. This commentary argues that the LCP has great qualitative utility in correctly…

  5. Ventilation Guidance To Promote the Safe Use of Spray Polyurethane Foam (SPF) Insulation, Incluyendo la Versión de Español

    EPA Pesticide Factsheets

    This guidance describes basic ventilation principles and strategies to help protect workers and building occupants and promote the safe use of spray polyurethane foam (SPF) insulation. Guia para la ventilacion sobre la application del aerosol de espuma.

  6. School Bus Safety.

    ERIC Educational Resources Information Center

    Stroup, Karen Bruner; And Others

    1991-01-01

    Equipment to allow safe transportation of disabled children is reviewed. Such equipment includes infant car seats, child safety seats, safety vests, and accommodations for children in casts and/or braces. Five principles for evaluation and selection of safe seating options are given as are safety rules and information on standards and resources.…

  7. Perseverations on a critical theme.

    PubMed

    Lustig, B A

    1993-10-01

    In response to my earlier critique of recent attempts to rebut principlism as an ethical approach, Green, Gert, and Clouser (GG&C) have in turn offered their own critique of my appraisal. This essay identifies eight major criticisms GG&C raise in their response and offers a rejoinder to each. Among them, three are especially important: (1) that the label of 'deductivism' fails to capture GG&C's ethical method and should be replaced by 'descriptivism'; (2) that pluralistic accounts, including principlism, fail to offer any systematic way to resolve moral conflicts; and (3) that appeals to broader 'moral' principles beyond the moral rules are deceiving, since apparent differences in 'moral' judgment invariably involve disagreement about empirical facts rather than further moral considerations. In response to (1), I defend my earlier label by emphasizing the stipulated and invariant status of the moral rules GG&C invoke, even as I question the adequacy of their putative 'descriptivism'. In response to (2), I suggest the plausibility of pluralist approaches and reiterate the modified just-war criteria that Beauchamp and Childress invoke in situations when principles conflict. In response to (3), I suggest that a 'descriptivism' worthy of the name must systematically accommodate the appeal to moral principles that remains central to metaethical and normative discussions.

  8. Recreation and Leisure.

    ERIC Educational Resources Information Center

    Lieberman, Lauren

    1995-01-01

    This brief guide presents principles and suggestions to help individuals who are deaf-blind enjoy and benefit from participation in recreational activities. Principles consider the need to: (1) start with the individual and determine what he/she is interested in, focusing on the selection of safe, age-appropriate activities; (2) research the…

  9. 32 CFR 634.26 - Traffic law enforcement principles.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... safely within traffic laws and regulations and maintain an effective and efficient flow of traffic... 32 National Defense 4 2013-07-01 2013-07-01 false Traffic law enforcement principles. 634.26... ENFORCEMENT AND CRIMINAL INVESTIGATIONS MOTOR VEHICLE TRAFFIC SUPERVISION Traffic Supervision § 634.26 Traffic...

  10. 32 CFR 634.26 - Traffic law enforcement principles.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... safely within traffic laws and regulations and maintain an effective and efficient flow of traffic... 32 National Defense 4 2012-07-01 2011-07-01 true Traffic law enforcement principles. 634.26... ENFORCEMENT AND CRIMINAL INVESTIGATIONS MOTOR VEHICLE TRAFFIC SUPERVISION Traffic Supervision § 634.26 Traffic...

  11. 32 CFR 634.26 - Traffic law enforcement principles.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... safely within traffic laws and regulations and maintain an effective and efficient flow of traffic... 32 National Defense 4 2014-07-01 2013-07-01 true Traffic law enforcement principles. 634.26... ENFORCEMENT AND CRIMINAL INVESTIGATIONS MOTOR VEHICLE TRAFFIC SUPERVISION Traffic Supervision § 634.26 Traffic...

  12. Scalable and fail-safe deployment of the ATLAS Distributed Data Management system Rucio

    NASA Astrophysics Data System (ADS)

    Lassnig, M.; Vigne, R.; Beermann, T.; Barisits, M.; Garonne, V.; Serfon, C.

    2015-12-01

    This contribution details the deployment of Rucio, the ATLAS Distributed Data Management system. The main complication is that Rucio interacts with a wide variety of external services, and connects globally distributed data centres under different technological and administrative control, at an unprecedented data volume. It is therefore not possible to create a duplicate instance of Rucio for testing or integration. Every software upgrade or configuration change is thus potentially disruptive and requires fail-safe software and automatic error recovery. Rucio uses a three-layer scaling and mitigation strategy based on quasi-realtime monitoring. This strategy mainly employs independent stateless services, automatic failover, and service migration. The technologies used for deployment and mitigation include OpenStack, Puppet, Graphite, HAProxy and Apache. In this contribution, the interplay between these components, their deployment, software mitigation, and the monitoring strategy are discussed.

  13. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bai, Xian-Xu, E-mail: bai@hfut.edu.cn; Wereley, Norman M.

    Magnetorheological (MR) energy absorbers (EAs) are an effective adaptive EA technology with which to maximize shock and vibration isolation. However, to realize maximum performance of the semi-active control system, the off-state (i.e., field off) stroking load of the MREA must be minimized at all speeds, and the dynamic range of the MREA must be maximized at high speed. This study presents a fail-safe MREA (MREA-FS) concept that, can produce a greater dynamic range at all piston speeds. A bias damping force is generated in the MREA-FS using permanent magnetic fields, which enables fail-safe behavior in the case of power failure.more » To investigate the feasibility and capability of the MREA-FS in the context of the semi-active control systems, a single-degree-of-freedom base excited rigid payload is mathematically constructed and simulated with skyhook control.« less

  14. Time-saving and fail-safe dissection method for vestibulocochlear organs in gross anatomy classes.

    PubMed

    Suzuki, Ryoji; Konno, Naoaki; Ishizawa, Akimitsu; Kanatsu, Yoshinori; Funakoshi, Kodai; Akashi, Hideo; Zhou, Ming; Abe, Hiroshi

    2017-09-01

    Because the vestibulocochlear organs are tiny and complex, and are covered by the petrous part of the temporal bone, they are very difficult for medical students to dissect and visualize during gross anatomy classes. Here, we report a time-saving and fail-safe procedure we have devised, using a hand-held hobby router. Nine en bloc temporal bone samples from donated human cadavers were used as trial materials for devising an appropriate procedure for dissecting the vestibulocochlear organs. A hand-held hobby router was used to cut through the temporal bone. After trials, the most time-saving and fail-safe method was selected. The performance of the selected method was assessed by a survey of 242 sides of 121 cadavers during gross anatomy classes for vestibulocochlear dissection. The assessment was based on the observation ratio. The best procedure appeared to be removal of the external acoustic meatus roof and tympanic cavity roof together with removal of the internal acoustic meatus roof. The whole procedure was completed within two dissection classes, each lasting 4.5 hr. The ratio of surveillance for the chorda tympani and three semicircular canals by students was significantly improved during 2013 through 2016. In our dissection class, "removal of the external acoustic meatus roof and tympanic cavity roof together with removal of the internal acoustic meatus roof" was the best procedure for students in the limited time available. Clin. Anat. 30:703-710, 2017. © 2017Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  15. 46th Annual Gun and Missile Systems Conference and Exhibition. Volume 3 - Thursday

    DTIC Science & Technology

    2011-09-01

    Grade Sensors Through Use of Accelerated Aging Principles Mr. Scott Gift 11657 Modeling of the Autofrettage Processes of a Gun Barrel Mr. Sudhir...Emissions Measured on the Outer Portion of a Composite Barrel Ms. Rushie Ghimire GUN & MISSILE SYSTEMS ADDITIONAL AUTHORS GUN & MISSILE SYSTEMS...Transportation – Loading – Gun Fire to Barrel Exit – After Barrel Exit • Passing: Fuze safety devices remain safe; safe for disposal or safe for

  16. Application of Hazard Analysis Critical Control Point in the local manufacture of ready-to-use therapeutic foods (RUTFs).

    PubMed

    Henry, C Jeya K; Xin, Janice Lim Wen

    2014-06-01

    The local manufacture of ready-to-use therapeutic foods (RUTFs) is increasing, and there is a need to develop methods to ensure their safe production. We propose the application of Hazard Analysis Critical Control Point (HACCP) principles to achieve this goal. The basic principles of HACCP in the production of RUTFs are outlined. It is concluded that the implementation of an HACCP system in the manufacture of RUTFs is not only feasible but also attainable. The introduction of good manufacturing practices, coupled with an effective HACCP system, will ensure that RUTFs are produced in a cost-effective, safe, and hygienic manner.

  17. Primary care and addiction treatment: lessons learned from building bridges across traditions.

    PubMed

    Stanley, A H

    1999-01-01

    A primary care unit combined with residential addiction treatment allows patients with addictive disease and chronic medical or psychiatric problems to successfully complete the treatment. These are patients who would otherwise fail treatment or fail to be considered candidates for treatment. Health care providers should have a background in primary care and have the potential to respond professionally to clinical problems in behavioral medicine. Ongoing professional training and statistical quality management principles can maintain morale and productivity. Health education is an integral part of primary care. The costs of such concurrent care when viewed in the context of the high societal and economic costs of untreated addictive disease and untreated chronic medical problems are low. The principles used to develop this primary care unit can be used to develop health care units for other underserved populations. These principles include identification of specific health care priorities and continuity of rapport with the target population and with addiction treatment staff.

  18. Better with Byzantine: Manipulation-Optimal Mechanisms

    NASA Astrophysics Data System (ADS)

    Othman, Abraham; Sandholm, Tuomas

    A mechanism is manipulable if it is in some agents’ best interest to misrepresent their private information. The revelation principle establishes that, roughly, anything that can be accomplished by a manipulable mechanism can also be accomplished with a truthful mechanism. Yet agents often fail to play their optimal manipulations due to computational limitations or various flavors of incompetence and cognitive biases. Thus, manipulable mechanisms in particular should anticipate byzantine play. We study manipulation-optimal mechanisms: mechanisms that are undominated by truthful mechanisms when agents act fully rationally, and do better than any truthful mechanism if any agent fails to act rationally in any way. This enables the mechanism designer to do better than the revelation principle would suggest, and obviates the need to predict byzantine agents’ irrational behavior. We prove a host of possibility and impossibility results for the concept which have the impression of broadly limiting possibility. These results are largely in line with the revelation principle, although the considerations are more subtle and the impossibility not universal.

  19. Mars Seasonal Polar Caps as a Test of the Equivalence Principle

    NASA Technical Reports Server (NTRS)

    Rubincam, Daivd Parry

    2011-01-01

    The seasonal polar caps of Mars can be used to test the equivalence principle in general relativity. The north and south caps, which are composed of carbon dioxide, wax and wane with the seasons. If the ratio of the inertial to gravitational masses of the caps differs from the same ratio for the rest of Mars, then the equivalence principle fails, Newton's third law fails, and the caps will pull Mars one way and then the other with a force aligned with the planet's spin axis. This leads to a secular change in Mars's along-track position in its orbit about the Sun, and to a secular change in the orbit's semimajor axis. The caps are a poor E6tv6s test of the equivalence principle, being 4 orders-of-magnitude weaker than laboratory tests and 7 orders-of-magnitude weaker than that found by lunar laser ranging; the reason is the small mass of the caps compared to Mars as a whole. The principal virtue of using Mars is that the caps contain carbon, an element not normally considered in such experiments. The Earth with its seasonal snow cover can also be used for a similar test.

  20. Safe use of cellular telephones in hospitals: fundamental principles and case studies.

    PubMed

    Cohen, Ted; Ellis, Willard S; Morrissey, Joseph J; Bakuzonis, Craig; David, Yadin; Paperman, W David

    2005-01-01

    Many industries and individuals have embraced cellular telephones. They provide mobile, synchronous communication, which could hypothetically increase the efficiency and safety of inpatient healthcare. However, reports of early analog cellular telephones interfering with critical life-support machines had led many hospitals to strictly prohibit cellular telephones. A literature search revealed that individual hospitals now are allowing cellular telephone use with various policies to prevent electromagnetic interference with medical devices. The fundamental principles underlying electromagnetic interference are immunity, frequency, modulation technology, distance, and power Electromagnetic interference risk mitigation methods based on these principles have been successfully implemented. In one case study, a minimum distance between cellular telephones and medical devices is maintained, with restrictions in critical areas. In another case study, cellular telephone coverage is augmented to automatically control the power of the cellular telephone. While no uniform safety standard yet exists, cellular telephones can be safely used in hospitals when their use is managed carefully.

  1. Fail-safe fire detection system

    NASA Technical Reports Server (NTRS)

    Bloam, E. T.

    1974-01-01

    Fire detection control system continually monitors its own integrity, automatically signals any malfunction, and separately signals fire in any zone being monitored. Should be of interest in fields of chemical and petroleum processing, power generation, equipment testing, and building protection.

  2. Design, Qualification and Lessons Learned of the Shutter Calibration Mechanism for EnMAP Mission

    NASA Astrophysics Data System (ADS)

    Schmidt, Tilo; Muller, Silvio; Bergander, Arvid; Zajac, Kai; Seifart, Klaus

    2015-09-01

    The Shutter Calibration Mechanism (SCM) Assembly is one of three mechanisms which are developed by HTS for the EnMAP instrument in subcontract to OHB System AG Munich. EnMAP is the Environmental Mapping and Analysis Program of the German Space Agency DLR.The binary rotary encoder of the SCM using hall-effect sensors was already presented during ESMATS 2011. This paper summarizes the main functions and design features of the Hardware and focuses on qualification testing which has finished successfully in 2014. Of particular interest is the functional testing of the main drive including the precise hall-effect position sensing system and the test of the fail safe mechanism. In addition to standard test campaign required for QM also a shock emission measurement of the fail safe mechanism activation was conducted.Test conduction and results will be presented with focus on deviations from the expected behaviour, mitigation measures and on lessons learned.

  3. CAT-tailing as a fail-safe mechanism for efficient degradation of stalled nascent polypeptides

    PubMed Central

    Kostova, Kamena K.; Hickey, Kelsey L.; Osuna, Beatriz A.; Hussmann, Jeffrey A.; Frost, Adam; Weinberg, David E.; Weissman, Jonathan S.

    2017-01-01

    Ribosome stalling leads to recruitment of the Ribosome Quality control Complex (RQC), which targets the partially synthesized polypeptide for proteasomal degradation through the action of the ubiquitin ligase Ltn1p. A second core RQC component, Rqc2p, modifies the nascent polypeptide by adding a Carboxy-terminal Alanine and Threonine (CAT) tail through a non-canonical elongation reaction. Here we explore the role of CATtailing in nascent-chain degradation in budding yeast. We show that Ltn1p can efficiently access only nascent chain lysines immediately proximal to the ribosome exit tunnel. For substrates without Ltn1p-accessible lysines, CAT-tailing enables degradation by exposing lysines sequestered in the ribosome exit tunnel. Thus, CAT-tails do not serve as a degron, but rather provide a fail-safe mechanism that expands the range of RQC-degradable substrates. PMID:28751611

  4. Safe Use of Hydrogen and Hydrogen Systems

    NASA Technical Reports Server (NTRS)

    Maes, Miguel

    2006-01-01

    This is a viewgraph presentation that is a course for teaching the safe use of hydrogen. The objectives of the course are 1. To familiarize the student with H2 safety properties 2. To enable the identification, evaluations and addressing of H2 system hazards 3. To teach: a. Safe practices for, b. Design, c. Materials selection, d. H2 system operation, e. Physical principles and empirical observations on which these safe practices are based, f. How to respond to emergency situations involving H2, g How to visualize safety concepts through in-class exercises, h. Identify numerous parameters important to H2 safety.

  5. Flight test and evaluation of Omega navigation for general aviation

    NASA Technical Reports Server (NTRS)

    Hwoschinsky, P. V.

    1975-01-01

    A seventy hour flight test program was performed to determine the suitability and accuracy of a low cost Omega navigation receiver in a general aviation aircraft. An analysis was made of signal availability in two widely separated geographic areas. Comparison is made of the results of these flights with other navigation systems. Conclusions drawn from the test experience indicate that developmental system improvement is necessary before a competent fail safe or fail soft area navigation system is offered to general aviation.

  6. Experimenting `learn by doing' and `learn by failing'

    NASA Astrophysics Data System (ADS)

    Pozzi, Rossella; Noè, Carlo; Rossi, Tommaso

    2015-01-01

    According to the literature, in recent years, developing experiential learning has fulfilled the requirement of a deep understanding of lean philosophy by engineering students, demonstrating the advantages and disadvantages of some of the key principles of lean manufacturing. On the other hand, the literature evidences how some kinds of game-based experiential learning overlook daily difficulties, which play a central role in manufacturing systems. To fill the need of a game overcoming such lack of vision, an innovative game direct in-field, named Kart Factory, has been developed. Actual production shifts are simulated, while keeping all the elements peculiar to a real production set (i.e. complexity, effort, safety). The working environment is a real pedal car assembly department, the products to be assembled have relevant size and weight (i.e. up to 35 kg approximately), and the provided tools are real production equipment (e.g. keys, screwdrivers, trans-pallets, etc.). Due to the need to maximise the impact on students, a labour-intensive process characterises the production department. The whole training process is based on three educational principles: Experience Value Principle, Error Value Principle, and Team Value Principle. As the 'learn by doing' and 'learn by failing' are favoured, the theory follows the practice, while crating the willingness to 'do' instead of just designing or planning. The gathered data prove the Kart Factory's effectiveness in reaching a good knowledge of lean concepts, notwithstanding the students' initial knowledge level.

  7. Environmental Action Guide for New York City Schools.

    ERIC Educational Resources Information Center

    Advocates for Children of New York, Inc., Long Island City.

    The purpose of this guide is to inform parents, advocates, and school personnel about existing laws and resources available to ensure that every child and every school employee has an environmentally safe and healthy school that is clean and in good repair. An environmentally safe and healthy school is one of the principles adopted by the New York…

  8. Principles of Safety in Physical Education and Sport. Revised Edition.

    ERIC Educational Resources Information Center

    Dougherty, Neil J., IV, Ed.

    The purpose of this book is to assist physical education teachers in the development and implementation of a safe and well-balanced program of activities and to provide students with information about safe participation in common sports. Using a checklist format, information is presented to facilitate the development of unit and lesson plans. The…

  9. Safe School Design: A Handbook for Educational Leaders Applying the Principles of Crime Prevention through Environmental Design.

    ERIC Educational Resources Information Center

    Schneider, Tod; Walker, Hill; Sprague, Jeffrey

    This document seeks to synthesize, integrate, and make available to school personnel solid information regarding Crime Prevention through Environmental Design (CPTED). Chapter 1, "The Changed Landscape of School Safety and Security," examines characteristics of safe and unsafe schools, causes of vulnerability, and the role of design and technology…

  10. Automated Testing Experience of the Linear Aerospike SR-71 Experiment (LASRE) Controller

    NASA Technical Reports Server (NTRS)

    Larson, Richard R.

    1999-01-01

    System controllers must be fail-safe, low cost, flexible to software changes, able to output health and status words, and permit rapid retest qualification. The system controller designed and tested for the aerospike engine program was an attempt to meet these requirements. This paper describes (1) the aerospike controller design, (2) the automated simulation testing techniques, and (3) the real time monitoring data visualization structure. Controller cost was minimized by design of a single-string system that used an off-the-shelf 486 central processing unit (CPU). A linked-list architecture, with states (nodes) defined in a user-friendly state table, accomplished software changes to the controller. Proven to be fail-safe, this system reported the abort cause and automatically reverted to a safe condition for any first failure. A real time simulation and test system automated the software checkout and retest requirements. A program requirement to decode all abort causes in real time during all ground and flight tests assured the safety of flight decisions and the proper execution of mission rules. The design also included health and status words, and provided a real time analysis interpretation for all health and status data.

  11. Collapsable seal member

    DOEpatents

    Sherrell, Dennis L.

    1990-01-01

    A hollow, collapsable seal member normally disposed in a natural expanded state offering fail-safe pressure sealing against a seating surface and adapted to be evacuated by a vacuum force for collapsing the seal member to disengage the same from said seating surface.

  12. Collapsable seal member

    DOEpatents

    Sherrell, D.L.

    1983-12-08

    A hollow, collapsable seal member normally disposed in a natural expanded state offering fail-safe pressure sealing against a seating surface and adapted to be evacuated by a vacuum force for collapsing the seal member to disengage the same from said seating surface.

  13. Photovoltaic power system reliability considerations

    NASA Technical Reports Server (NTRS)

    Lalli, V. R.

    1980-01-01

    An example of how modern engineering and safety techniques can be used to assure the reliable and safe operation of photovoltaic power systems is presented. This particular application is for a solar cell power system demonstration project designed to provide electric power requirements for remote villages. The techniques utilized involve a definition of the power system natural and operating environment, use of design criteria and analysis techniques, an awareness of potential problems via the inherent reliability and FMEA methods, and use of fail-safe and planned spare parts engineering philosophy.

  14. Parenteral nutrition combined with rice soup can be a safe and effective intervention for congenital chylous ascites.

    PubMed

    Cao, Yi; Yan, Weihui; Lu, Lina; Tao, Yijing; Lu, Wei; Chen, Yingwei; Tang, Qingya; Cai, Wei

    2016-01-01

    Congenital chylous ascites in the neonatal period is a rare entity. Total parenteral nutrition (TPN), medium chain triglyceride (MCT)-based diet, octreotide and repeated paracentesis are regarded as appropriate medical treatment for congenital chylous ascites, and surgery is recommended when conservative therapy has failed. We present two cases in which ascites were confirmed via an abdominal sonogram and diagnostic paracentesis. In our clinical experience, rice soup combined with PN can be a safe and effective intervention.

  15. Photovoltaic power system reliability considerations

    NASA Technical Reports Server (NTRS)

    Lalli, V. R.

    1980-01-01

    This paper describes an example of how modern engineering and safety techniques can be used to assure the reliable and safe operation of photovoltaic power systems. This particular application was for a solar cell power system demonstration project in Tangaye, Upper Volta, Africa. The techniques involve a definition of the power system natural and operating environment, use of design criteria and analysis techniques, an awareness of potential problems via the inherent reliability and FMEA methods, and use of a fail-safe and planned spare parts engineering philosophy.

  16. Volcanoes in the Classroom: Simulating an Eruption Column

    NASA Astrophysics Data System (ADS)

    Harpp, K. S.; Geist, D. J.; Koleszar, A. M.

    2005-12-01

    Few students have the opportunity to witness volcanic eruptions first hand. Analog models of eruptive processes provide ways for students to apply basic physical principles when field observations are not feasible. We describe a safe simulation of violent volcanic explosions, one that can be carried out simply and easily as a demonstration for specialized volcanology classes, introductory classes, and science outreach programs. Volcanic eruptions are fundamentally gas-driven phenomena. Depressurization of volatiles dissolved in magma during ascent is the driving force behind most explosive eruptions. We have developed a demonstration whereby the instructor can initiate a gas-driven eruption, which produces a dramatic but safe explosion and eruptive column. First, one pours liquid nitrogen into a weighted, plastic soda bottle, which is then sealed and placed into a trashcan filled with water. As the liquid nitrogen boils, the pressure inside the bottle increases until the seal fails, resulting in an explosion. The expansive force propels a column of water vertically, to 10 or more meters. Students can operate the demonstration themselves and carry out a sequence of self-designed variations, changing the vent size and viscosity of the "magma", for instance. They can also vary the material used as "tephra", studying the effects of projectile density, column height, and wind direction on tephra distribution. The physical measurements that students collect, such as column height and tephra radius, can be used as the basis for problem sets that explore the dynamics of eruption columns. Possible calculations include ejection velocity, the pressure needed to propel the water column, and average vesicularity of the "magma". Students can then compare their results to observations from real volcanic eruptions. We find this to be an exceedingly effective demonstration of gas-driven liquid explosions and one that is safe if done properly. [NOTE: Please do NOT attempt this demonstration without full, detailed instructions and safety precautions, see website resource below].

  17. Naval Classical Thinkers and Operational Art

    DTIC Science & Technology

    2009-01-01

    Principles and Practice of Military Operations on Land, published in 1911, did not attract as much attention as his previous two major works...thinker. He failed, for example, to consider factors such as social and cultural conditions in the rise of sea power; the rise of the English middle...three key ideas: the inherent value of a strategic central or interior position, the principle of concentration, and the close relationship between

  18. Mars seasonal polar caps as a test of the equivalence principle

    NASA Astrophysics Data System (ADS)

    Rubincam, David Parry

    2011-08-01

    The seasonal polar caps of Mars can be used to test the equivalence principle in general relativity. The north and south caps, which are composed of carbon dioxide, wax and wane with the seasons. If the ratio of the inertial (passive) to gravitational (active) masses of the caps differs from the same ratio for the rest of Mars, then the equivalence principle fails, Newton’s third law fails, and the caps will pull Mars one way and then the other with a force aligned with the planet’s spin axis. This leads to a secular change in Mars’s along-track position in its orbit about the Sun, and to a secular change in the orbit’s semimajor axis. The caps are a poor Eötvös test of the equivalence principle, being 4 orders-of-magnitude weaker than laboratory tests and 7 orders-of-magnitude weaker than that found by lunar laser ranging; the reason is the small mass of the caps compared to Mars as a whole. The principal virtue of using Mars is that the caps contain carbon, an element not normally considered in such experiments. The Earth with its seasonal snow cover can also be used for a similar test.

  19. Code of Practice for Scientific Diving: Principles for the Safe Practice of Scientific Diving in Different Environments. Unesco Technical Papers in Marine Science 53.

    ERIC Educational Resources Information Center

    Flemming, N. C., Ed.; Max, M. D., Ed.

    This publication has been prepared to provide scientific divers with guidance on safe practice under varying experimental and environmental conditions. The Code offers advice and recommendations on administrative practices, insurance, terms of employment, medical standards, training standards, dive planning, safety with different breathing gases…

  20. Millwright: Apprenticeship Course Outline. Apprenticeship and Industry Training. 1605.2

    ERIC Educational Resources Information Center

    Alberta Advanced Education and Technology, 2005

    2005-01-01

    The graduate of the Millwright apprenticeship program is a certified journeyperson who will be able to: (1) understand the principles of sound and safe trade practice; (2) interpret drawings, plans, and be able to layout and develop projects according to specifications; (3) use the tools of the trade in a safe and proper manner; (4) relate to the…

  1. Electric Motor Systems Technician: Apprenticeship Course Outline. Apprenticeship and Industry Training. 3006.2

    ERIC Educational Resources Information Center

    Alberta Advanced Education and Technology, 2006

    2006-01-01

    The graduate of the Electric Motor Systems Technician apprenticeship program is a certified journeyperson who will be able to: (1) understand the principles of sound and safe trade practices; (2) interpret drawings, plans, and be able to layout and develop projects according to specifications; (3) use the tools of the trade in a safe and proper…

  2. Towards an ethics safe harbor for global biomedical research

    PubMed Central

    Dove, Edward S.; Knoppers, Bartha M.; Zawati, Ma'n H.

    2014-01-01

    Although increasingly global, data-driven genomics and other ‘omics’-focused research hold great promise for health discoveries, current research ethics review systems around the world challenge potential improvements in human health from such research. To overcome this challenge, we propose a ‘Safe Harbor Framework for International Ethics Equivalency’ that facilitates the harmonization of ethics review of specific types of data-driven international research projects while respecting globally transposable research ethics norms and principles. The Safe Harbor would consist in part of an agency supporting an International Federation for Ethics Review (IFER), formed by a voluntary compact among countries, granting agencies, philanthropies, institutions, and healthcare, patient advocacy, and research organizations. IFER would be both a central ethics review body, and also a forum for review and follow-up of policies concerning ethics norms for international research projects. It would be built on five principle elements: (1) registration, (2) compliance review, (3) recognition, (4) monitoring and enforcement, and (5) public participation. The Safe Harbor would create many benefits for researchers, countries, and the general public, and may eventually have application beyond (gen)omics to other areas of biomedical research that increasingly engage in secondary use of data and present only negligible risks. PMID:27774154

  3. [The new Blood Law and new principles of transfusion therapy].

    PubMed

    Takahashi, Koki

    2005-01-01

    The new Blood Law for Self-sufficiency, Stable Supply of Safe Blood Products and Other Transfusion-related Rules was enacted in July 2003. In terms of the safety of blood products, improvement of screening tests and the introduction of the viral nucleic acid amplification test to shorten the so-called window period have markedly reduced the incidence of blood-borne virus transmission, although they cannot completely protect against transfusion-associated adverse reactions. Even with increasing blood safety, there remains an iatrogenic risk of ABO-mismatched transfusions without proper management systems and standard operation procedures. Fresh frozen plasma and plasma derivatives have been and continue to be used much more in Japan compared with the international standard. As a result, the shortage of domestic blood products remains an obstacle to achieving self-sufficiency. The goal of the new law is to provide safe transfusion therapy and achieve self-sufficiency in all blood products including plasma derivatives such as albumin solutions. To reach this goal medical professionals should recognize the necessity for safe and appropriate transfusions and establish new principles for improved transfusion therapy, including standard indications, safe operation procedure guidelines, and a 24-hour management system in each hospital.

  4. Obstetric Anaesthetists' Association and Difficult Airway Society guidelines for the management of difficult and failed tracheal intubation in obstetrics.

    PubMed

    Mushambi, M C; Kinsella, S M; Popat, M; Swales, H; Ramaswamy, K K; Winton, A L; Quinn, A C

    2015-11-01

    The Obstetric Anaesthetists' Association and Difficult Airway Society have developed the first national obstetric guidelines for the safe management of difficult and failed tracheal intubation during general anaesthesia. They comprise four algorithms and two tables. A master algorithm provides an overview. Algorithm 1 gives a framework on how to optimise a safe general anaesthetic technique in the obstetric patient, and emphasises: planning and multidisciplinary communication; how to prevent the rapid oxygen desaturation seen in pregnant women by advocating nasal oxygenation and mask ventilation immediately after induction; limiting intubation attempts to two; and consideration of early release of cricoid pressure if difficulties are encountered. Algorithm 2 summarises the management after declaring failed tracheal intubation with clear decision points, and encourages early insertion of a (preferably second-generation) supraglottic airway device if appropriate. Algorithm 3 covers the management of the 'can't intubate, can't oxygenate' situation and emergency front-of-neck airway access, including the necessity for timely perimortem caesarean section if maternal oxygenation cannot be achieved. Table 1 gives a structure for assessing the individual factors relevant in the decision to awaken or proceed should intubation fail, which include: urgency related to maternal or fetal factors; seniority of the anaesthetist; obesity of the patient; surgical complexity; aspiration risk; potential difficulty with provision of alternative anaesthesia; and post-induction airway device and airway patency. This decision should be considered by the team in advance of performing a general anaesthetic to make a provisional plan should failed intubation occur. The table is also intended to be used as a teaching tool to facilitate discussion and learning regarding the complex nature of decision-making when faced with a failed intubation. Table 2 gives practical considerations of how to awaken or proceed with surgery. The background paper covers recommendations on drugs, new equipment, teaching and training. © 2015 The Authors. Anaesthesia published by John Wiley & Sons Ltd on behalf of Association of Anaesthetists of Great Britain and Ireland.

  5. Obstetric Anaesthetists' Association and Difficult Airway Society guidelines for the management of difficult and failed tracheal intubation in obstetrics*

    PubMed Central

    Mushambi, M C; Kinsella, S M; Popat, M; Swales, H; Ramaswamy, K K; Winton, A L; Quinn, A C

    2015-01-01

    The Obstetric Anaesthetists' Association and Difficult Airway Society have developed the first national obstetric guidelines for the safe management of difficult and failed tracheal intubation during general anaesthesia. They comprise four algorithms and two tables. A master algorithm provides an overview. Algorithm 1 gives a framework on how to optimise a safe general anaesthetic technique in the obstetric patient, and emphasises: planning and multidisciplinary communication; how to prevent the rapid oxygen desaturation seen in pregnant women by advocating nasal oxygenation and mask ventilation immediately after induction; limiting intubation attempts to two; and consideration of early release of cricoid pressure if difficulties are encountered. Algorithm 2 summarises the management after declaring failed tracheal intubation with clear decision points, and encourages early insertion of a (preferably second-generation) supraglottic airway device if appropriate. Algorithm 3 covers the management of the ‘can't intubate, can't oxygenate’ situation and emergency front-of-neck airway access, including the necessity for timely perimortem caesarean section if maternal oxygenation cannot be achieved. Table 1 gives a structure for assessing the individual factors relevant in the decision to awaken or proceed should intubation fail, which include: urgency related to maternal or fetal factors; seniority of the anaesthetist; obesity of the patient; surgical complexity; aspiration risk; potential difficulty with provision of alternative anaesthesia; and post-induction airway device and airway patency. This decision should be considered by the team in advance of performing a general anaesthetic to make a provisional plan should failed intubation occur. The table is also intended to be used as a teaching tool to facilitate discussion and learning regarding the complex nature of decision-making when faced with a failed intubation. Table 2 gives practical considerations of how to awaken or proceed with surgery. The background paper covers recommendations on drugs, new equipment, teaching and training. PMID:26449292

  6. Secured Advanced Federated Environment (SAFE): A NASA Solution for Secure Cross-Organization Collaboration

    NASA Technical Reports Server (NTRS)

    Chow, Edward; Spence, Matthew Chew; Pell, Barney; Stewart, Helen; Korsmeyer, David; Liu, Joseph; Chang, Hsin-Ping; Viernes, Conan; Gogorth, Andre

    2003-01-01

    This paper discusses the challenges and security issues inherent in building complex cross-organizational collaborative projects and software systems within NASA. By applying the design principles of compartmentalization, organizational hierarchy and inter-organizational federation, the Secured Advanced Federated Environment (SAFE) is laying the foundation for a collaborative virtual infrastructure for the NASA community. A key element of SAFE is the Micro Security Domain (MSD) concept, which balances the need to collaborate and the need to enforce enterprise and local security rules. With the SAFE approach, security is an integral component of enterprise software and network design, not an afterthought.

  7. Practices in Adequate Structural Design

    NASA Technical Reports Server (NTRS)

    Ryan, Robert S.

    1989-01-01

    Structural design and verification of space vehicles and space systems is a very tricky and awe inspiring business, particularly for manned missions. Failures in the missions with loss of life is devastating personally and nationally. The scope of the problem is driven by high performance requirements which push state-of-the-art technologies, creating high sensitivites to small variations and uncertainties. Insurance of safe, reliable flight dictates the use of sound principles, procedures, analysis, and testing. Many of those principles which were refocused by the Space Shuttle Challenger (51-L) accident on January 26, 1986, and the activities conducted to insure safe shuttle reflights are discussed. The emphasis will be focused on engineering, while recognizing that project and project management are also key to success.

  8. Practices in adequate structural design

    NASA Astrophysics Data System (ADS)

    Ryan, Robert S.

    1989-01-01

    Structural design and verification of space vehicles and space systems is a very tricky and awe inspiring business, particularly for manned missions. Failures in the missions with loss of life is devastating personally and nationally. The scope of the problem is driven by high performance requirements which push state-of-the-art technologies, creating high sensitivites to small variations and uncertainties. Insurance of safe, reliable flight dictates the use of sound principles, procedures, analysis, and testing. Many of those principles which were refocused by the Space Shuttle Challenger (51-L) accident on January 26, 1986, and the activities conducted to insure safe shuttle reflights are discussed. The emphasis will be focused on engineering, while recognizing that project and project management are also key to success.

  9. Using Participatory Action Research to Develop a Working Model That Enhances Psychiatric Nurses' Professionalism: The Architecture of Stability.

    PubMed

    Salzmann-Erikson, Martin

    2017-11-01

    Ward rules in psychiatric care aim to promote safety for both patients and staff. Simultaneously, ward rules are associated with increased patient violence, leading to neither a safe work environment nor a safe caring environment. Although ward rules are routinely used, few studies have explicitly accounted for their impact. To describe the process of a team development project considering ward rule issues, and to develop a working model to empower staff in their daily in-patient psychiatric nursing practices. The design of this study is explorative and descriptive. Participatory action research methodology was applied to understand ward rules. Data consists of audio-recorded group discussions, observations and field notes, together creating a data set of 556 text pages. More than 100 specific ward rules were identified. In this process, the word rules was relinquished in favor of adopting the term principles, since rules are inconsistent with a caring ideology. A linguistic transition led to the development of a framework embracing the (1) Principle of Safety, (2) Principle of Structure and (3) Principle of Interplay. The principles were linked to normative guidelines and applied ethical theories: deontology, consequentialism and ethics of care. The work model reminded staff about the principles, empowered their professional decision-making, decreased collegial conflicts because of increased acceptance for individual decisions, and, in general, improved well-being at work. Furthermore, the work model also empowered staff to find support for their decisions based on principles that are grounded in the ethics of totality.

  10. Identification, analysis, and remedial treatment of low guardrail in Virginia.

    DOT National Transportation Integrated Search

    1981-01-01

    Guardrails that are too low may fail to safely redirect errant vehicles; instead, the vehicles may vault the guardrails, resulting in severe accidents. An analysis of data on a small sample of guardrails throughout-Virginia showed that over 80% of th...

  11. 77 FR 6122 - Providing Refurbishment Services to Federal Agencies

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-07

    ... equipment? 5. Describe the process for disposing and recycling of failed equipment. Have all facilities in your recycling and disposal process been certified to safely recycle and manage electronics? If so... firms offering refurbishment services, including those developed specifically for recycling facilities...

  12. Conscientious objection or fear of social stigma and unawareness of ethical obligations.

    PubMed

    Faúndes, Anibal; Duarte, Graciana Alves; Osis, Maria José Duarte

    2013-12-01

    Conscientious objection is a legitimate right of physicians to reject the practice of actions that violate their ethical or moral principles. The application of that principle is being used in many countries as a justification to deny safe abortion care to women who have the legal right to have access to safe termination of pregnancy. The problem is that, often, this concept is abused by physicians who camouflage under the guise of conscientious objection their fear of experiencing discrimination and social stigma if they perform legal abortions. These colleagues seem to ignore the ethical principle that the primary conscientious duty of OB/GYNs is-at all times-to treat, or provide benefit and prevent harm to, the patients for whose care they are responsible. Any conscientious objection to treating a patient is secondary to this primary duty. One of the jobs of the FIGO Working Group for the Prevention of Unsafe Abortion is to change this paradigm and make our colleagues proud of providing legal abortion services that protect women's life and health, and concerned about disrespecting the human rights of women and professional ethical principles. Copyright © 2013 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.

  13. A review of selected pumping systems in nature and engineering--potential biomimetic concepts for improving displacement pumps and pulsation damping.

    PubMed

    Bach, D; Schmich, F; Masselter, T; Speck, T

    2015-09-03

    The active transport of fluids by pumps plays an essential role in engineering and biology. Due to increasing energy costs and environmental issues, topics like noise reduction, increase of efficiency and enhanced robustness are of high importance in the development of pumps in engineering. The study compares pumps in biology and engineering and assesses biomimetic potentials for improving man-made pumping systems. To this aim, examples of common challenges, applications and current biomimetic research for state-of-the art pumps are presented. The biomimetic research is helped by the similar configuration of many positive displacement pumping systems in biology and engineering. In contrast, the configuration and underlying pumping principles for fluid dynamic pumps (FDPs) differ to a greater extent in biology and engineering. However, progress has been made for positive displacement as well as for FDPs by developing biomimetic devices with artificial muscles and cilia that improve energetic efficiency and fail-safe operation or reduce noise. The circulatory system of vertebrates holds a high biomimetic potential for the damping of pressure pulsations, a common challenge in engineering. Damping of blood pressure pulsation results from a nonlinear viscoelastic behavior of the artery walls which represent a complex composite material. The transfer of the underlying functional principle could lead to an improvement of existing technical solutions and be used to develop novel biomimetic damping solutions. To enhance efficiency or thrust of man-made fluid transportation systems, research on jet propulsion in biology has shown that a pulsed jet can be tuned to either maximize thrust or efficiency. The underlying principle has already been transferred into biomimetic applications in open channel water systems. Overall there is a high potential to learn from nature in order to improve pumping systems for challenges like the reduction of pressure pulsations, increase of jet propulsion efficiency or the reduction of wear.

  14. Prototype data terminal: Multiplexer/demultiplexer

    NASA Technical Reports Server (NTRS)

    Leck, D. E.; Goodwin, J. E.

    1972-01-01

    The design and operation of a quad redundant data terminal and a multiplexer/demultiplexer (MDU) design are described. The most unique feature is the design of the quad redundant data terminal. This is one of the few designs where the unit is fail/op, fail/op, fail/safe. Laboratory tests confirm that the unit will operate satisfactorily with the failure of three out of four channels. Although the design utilizes state-of-the-art technology. The waveform error checks, the voting techniques, and the parity bit checks are believed to be used in unique configurations. Correct word selection routines are also novel, if not unique. The MDU design, while not redundant, utilizes, the latest state-of-the-art advantages of light couplers and integrated circuit amplifiers.

  15. [Anniversary of the medical department of the Federal Office for Safe Storage and Destruction of Chemical Weapons].

    PubMed

    Kuz'menko, I E

    2013-01-01

    The article is devoted to the process of formation and development of CW destruction management system and medical support of professional activities of personnel. Founders of Medical department of the Federal Directorate for Safe Storage and Destruction of Chemical Weapons are presented. Main principles and ways of working of medical department in specific conditions are covered.

  16. Safe and Effective Secondary Schools: The Boys Town Model. Preventing Violence, Building Respect, and Promoting Learning in the Classroom and Beyond.

    ERIC Educational Resources Information Center

    Davis, Jerry L., Ed.; Nelson, Cathy S., Ed.; Gauger, Elizabeth S., Ed.

    This book presents useful information on types and levels of aggression, how conflicts escalate, early warning signs of violence, and characteristics of a safe school. Violence prevention techniques, many based on principles that form the foundation of the Boys Town Education Model, show educators and administrators how to calm an angry or…

  17. Transportation-Related Safety Behaviors in Top-Grossing Children's Movies from 2008 to 2013.

    PubMed

    Boppana, Shilpa; Shen, Jiabin; Schwebel, David C

    2016-05-01

    Children regularly imitate behavior from movies. The authors assessed injury risk behaviors in top-grossing children's films. The 5 top-grossing G- or PG-rated movies annually from 2008 to 2013 were included, including animated movies and those set in the past/future. Researchers coded transportation scenes for risk taking in 3 domains: protection/equipment, unsafe behaviors, and distraction/attention. Safe and risky behaviors were recorded across the 3 domains. With regard to protection and equipment, 20% of motor vehicle scenes showed characters riding without seat belts and 27% of scenes with motorcycles showed characters riding without helmets. Eighty-nine percent of scenes with horses showed riders without helmets and 67% of boat operators failed to wear personal flotation devices. The most common unsafe behaviors were speeding and unsafe street-crossing. Twenty-one percent of scenes with motor vehicles showed drivers speeding and 90% of pedestrians in films failed to wait for signal changes. Distracted and inattentive behaviors were rare, with distracted driving of motor vehicles occurring in only approximately 2% of total driving scenes. Although many safe transportation behaviors were portrayed, the film industry continues to depict unsafe behaviors in movies designed for pediatric audiences. There is a need for the film industry to continue to balance entertainment and art with modeling of safe behavior for children.

  18. Fatigue analysis of composite materials using the fail-safe concept

    NASA Technical Reports Server (NTRS)

    Stievenard, G.

    1982-01-01

    If R1 is the probability of having a crack on a flight component and R2 is the probability of seeing this crack propagate between two scheduled inspections, the global failure regulation states that this product must not exceed 0.0000001.

  19. Voter comparator switch provides fail safe data communications system - A concept

    NASA Technical Reports Server (NTRS)

    Koczela, L. J.; Wilgus, D. S.

    1971-01-01

    System indicates status of computers and controls operational modes. Two matrices are used - one relating to permissible system states, the other relating to requested system states. Concept is useful to designers of digital data transmission systems and time shared computer systems.

  20. Verification Methodology of Fault-tolerant, Fail-safe Computers Applied to MAGLEV Control Computer Systems

    DOT National Transportation Integrated Search

    1993-05-01

    The Maglev control computer system should be designed to verifiably possess high reliability and safety as well as high availability to make Maglev a dependable and attractive transportation alternative to the public. A Maglev computer system has bee...

  1. CAT-tailing as a fail-safe mechanism for efficient degradation of stalled nascent polypeptides.

    PubMed

    Kostova, Kamena K; Hickey, Kelsey L; Osuna, Beatriz A; Hussmann, Jeffrey A; Frost, Adam; Weinberg, David E; Weissman, Jonathan S

    2017-07-28

    Ribosome stalling leads to recruitment of the ribosome quality control complex (RQC), which targets the partially synthesized polypeptide for proteasomal degradation through the action of the ubiquitin ligase Ltn1p. A second core RQC component, Rqc2p, modifies the nascent polypeptide by adding a carboxyl-terminal alanine and threonine (CAT) tail through a noncanonical elongation reaction. Here we examined the role of CAT-tailing in nascent-chain degradation in budding yeast. We found that Ltn1p efficiently accessed only nascent-chain lysines immediately proximal to the ribosome exit tunnel. For substrates without Ltn1p-accessible lysines, CAT-tailing enabled degradation by exposing lysines sequestered in the ribosome exit tunnel. Thus, CAT-tails do not serve as a degron, but rather provide a fail-safe mechanism that expands the range of RQC-degradable substrates. Copyright © 2017 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

  2. The fail-safe mechanism of post-transcriptional silencing of unspliced HAC1 mRNA.

    PubMed

    Di Santo, Rachael; Aboulhouda, Soufiane; Weinberg, David E

    2016-10-01

    HAC1 encodes a transcription factor that is the central effector of the unfolded protein response (UPR) in budding yeast. When the UPR is inactive, HAC1 mRNA is stored as an unspliced isoform in the cytoplasm and no Hac1 protein is detectable. Intron removal is both necessary and sufficient to relieve the post-transcriptional silencing of HAC1 mRNA, yet the precise mechanism by which the intron prevents Hac1 protein accumulation has remained elusive. Here, we show that a combination of inhibited translation initiation and accelerated protein degradation-both dependent on the intron-prevents the accumulation of Hac1 protein when the UPR is inactive. Functionally, both components of this fail-safe silencing mechanism are required to prevent ectopic production of Hac1 protein and concomitant activation of the UPR. Our results provide a mechanistic understanding of HAC1 regulation and reveal a novel strategy for complete post-transcriptional silencing of a cytoplasmic mRNA.

  3. The precautionary principle: is it safe.

    PubMed

    Gignon, Maxime; Ganry, Olivier; Jardé, Olivier; Manaouil, Cécile

    2013-06-01

    The precautionary principle is generally acknowledged to be a powerful tool for protecting health but it was originally invoked by policy makers for dealing with environmental issues. In the 1990s, the principle was incorporated into many legislative and regulatory texts in international law. One can consider that the precautionary principle has turned into "precautionism" necessary to prove to the people, taking account of risk in decisions. There is now a risk that these abuses will deprive the principle of its meaning and value. When pushed to its limits, the precautionary principle can even be dangerous when applied to the healthcare field. This is why a critical analysis of the principle is necessary. Through the literature, it sometimes seems to deviate somehow from the essence of the precautionary principle as it is commonly used in relation to health. We believe that educational work is necessary to familiarize professionals, policy makers and public opinion of the precautionary principle and avoid confusion. We propose a critical analysis of the use and misuse of the precautionary principle.

  4. Guidelines and Recommendations for Developing Interactive eHealth Apps for Complex Messaging in Health Promotion.

    PubMed

    Heffernan, Kayla Joanne; Chang, Shanton; Maclean, Skye Tamara; Callegari, Emma Teresa; Garland, Suzanne Marie; Reavley, Nicola Jane; Varigos, George Andrew; Wark, John Dennis

    2016-02-09

    The now ubiquitous catchphrase, "There's an app for that," rings true owing to the growing number of mobile phone apps. In excess of 97,000 eHealth apps are available in major app stores. Yet the effectiveness of these apps varies greatly. While a minority of apps are developed grounded in theory and in conjunction with health care experts, the vast majority are not. This is concerning given the Hippocratic notion of "do no harm." There is currently no unified formal theory for developing interactive eHealth apps, and development is especially difficult when complex messaging is required, such as in health promotion and prevention. This paper aims to provide insight into the creation of interactive eHealth apps for complex messaging, by leveraging the Safe-D case study, which involved complex messaging required to guide safe but sufficient UV exposure for vitamin D synthesis in users. We aim to create recommendations for developing interactive eHealth apps for complex messages based on the lessons learned during Safe-D app development. For this case study we developed an Apple and Android app, both named Safe-D, to safely improve vitamin D status in young women through encouraging safe ultraviolet radiation exposure. The app was developed through participatory action research involving medical and human computer interaction researchers, subject matter expert clinicians, external developers, and target users. The recommendations for development were created from analysis of the development process. By working with clinicians and implementing disparate design examples from the literature, we developed the Safe-D app. From this development process, recommendations for developing interactive eHealth apps for complex messaging were created: (1) involve a multidisciplinary team in the development process, (2) manage complex messages to engage users, and (3) design for interactivity (tailor recommendations, remove barriers to use, design for simplicity). This research has provided principles for developing interactive eHealth apps for complex messaging as guidelines by aggregating existing design concepts and expanding these concepts and new learnings from our development process. A set of guidelines to develop interactive eHealth apps generally, and specifically those for complex messaging, was previously missing from the literature; this research has contributed these principles. Safe-D delivers complex messaging simply, to aid education, and explicitly, considering user safety.

  5. Guidelines and Recommendations for Developing Interactive eHealth Apps for Complex Messaging in Health Promotion

    PubMed Central

    Heffernan, Kayla Joanne; Maclean, Skye Tamara; Callegari, Emma Teresa; Garland, Suzanne Marie; Reavley, Nicola Jane; Varigos, George Andrew; Wark, John Dennis

    2016-01-01

    Background The now ubiquitous catchphrase, “There’s an app for that,” rings true owing to the growing number of mobile phone apps. In excess of 97,000 eHealth apps are available in major app stores. Yet the effectiveness of these apps varies greatly. While a minority of apps are developed grounded in theory and in conjunction with health care experts, the vast majority are not. This is concerning given the Hippocratic notion of “do no harm.” There is currently no unified formal theory for developing interactive eHealth apps, and development is especially difficult when complex messaging is required, such as in health promotion and prevention. Objective This paper aims to provide insight into the creation of interactive eHealth apps for complex messaging, by leveraging the Safe-D case study, which involved complex messaging required to guide safe but sufficient UV exposure for vitamin D synthesis in users. We aim to create recommendations for developing interactive eHealth apps for complex messages based on the lessons learned during Safe-D app development. Methods For this case study we developed an Apple and Android app, both named Safe-D, to safely improve vitamin D status in young women through encouraging safe ultraviolet radiation exposure. The app was developed through participatory action research involving medical and human computer interaction researchers, subject matter expert clinicians, external developers, and target users. The recommendations for development were created from analysis of the development process. Results By working with clinicians and implementing disparate design examples from the literature, we developed the Safe-D app. From this development process, recommendations for developing interactive eHealth apps for complex messaging were created: (1) involve a multidisciplinary team in the development process, (2) manage complex messages to engage users, and (3) design for interactivity (tailor recommendations, remove barriers to use, design for simplicity). Conclusions This research has provided principles for developing interactive eHealth apps for complex messaging as guidelines by aggregating existing design concepts and expanding these concepts and new learnings from our development process. A set of guidelines to develop interactive eHealth apps generally, and specifically those for complex messaging, was previously missing from the literature; this research has contributed these principles. Safe-D delivers complex messaging simply, to aid education, and explicitly, considering user safety. PMID:26860623

  6. Forensic engineering: applying materials and mechanics principles to the investigation of product failures.

    PubMed

    Hainsworth, S V; Fitzpatrick, M E

    2007-06-01

    Forensic engineering is the application of engineering principles or techniques to the investigation of materials, products, structures or components that fail or do not perform as intended. In particular, forensic engineering can involve providing solutions to forensic problems by the application of engineering science. A criminal aspect may be involved in the investigation but often the problems are related to negligence, breach of contract, or providing information needed in the redesign of a product to eliminate future failures. Forensic engineering may include the investigation of the physical causes of accidents or other sources of claims and litigation (for example, patent disputes). It involves the preparation of technical engineering reports, and may require giving testimony and providing advice to assist in the resolution of disputes affecting life or property.This paper reviews the principal methods available for the analysis of failed components and then gives examples of different component failure modes through selected case studies.

  7. EPSRC Principles of Robotics: defending an obsolete human(ism)?

    NASA Astrophysics Data System (ADS)

    Szollosy, Michael

    2017-04-01

    The EPSRC Principles of Robotics (2010), whatever noble intentions, failed to create an enduring set of principles for research into and development of robotics and artificial intelligence because those participating in the workshop did not begin with an adequate understanding of what it means to be "human". Labouring under the false, outdated assumptions of humanism, the human beings that the Principles are meant to serve have never existed in such an overly-simplistic form, or are soon to be made extinct by the transformative power of new technologies, and new ways of imagining human social relations in response to technological innovation. At the heart of any principles for robotics must be a new, more flexible conception of what it means to be human, and a recognition that human beings are, and always will be, plural and contingent.

  8. Economic Sanctions: A Failing Instrument of United States Foreign Policy.

    DTIC Science & Technology

    1992-04-01

    couldn’t achieve--a controlling share of the world’s oil market. 4 Saddam’s military machine was fundmental to his quest to gain and hold power, to...Four principles guide our policy. First, we seek the immediate, unconditional and complete withdrawal of all Iraqi forces from Kuwait. Second...determined to protect the lives of American citizens abroad." The interpretation of these principles or objectives would be the subject of continuous debate

  9. Modernization of the Defense Sector. Principles and Characteristics of the Argentine Model

    DTIC Science & Technology

    2007-01-01

    penalty for failing to comply with a collection of information if it does not display a currently valid OMB control number. 1. REPORT DATE 2001 2...Armed Forces according to democratic rules –especially in compliance with the principle of sub- ordination to civilian control and the limited assign...domestic sphere. os armados en el plano interno . Derived from such complex scenario, we find an array of demands the Ministry of Defense must

  10. Description and comparative evaluation of a proposed design for the low visibility approach study

    DOT National Transportation Integrated Search

    1985-10-01

    Ths memorandum was prepared in support of the low visibility simulation study being : conducted by the FAA as a basis for establishing the lowest RVR (runway visual range) : required for safe, fail passive auto landings in Category III weather. A des...

  11. 78 FR 57542 - Airworthiness Directives; The Boeing Company Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-19

    ... cracked retract actuator fuse pins that could fail earlier than the previously determined safe life limit... 5 p.m., Monday through Friday, except Federal holidays. For service information identified in this proposed AD, contact Boeing Commercial Airplanes, Attention: Data & Services Management, P.O. Box 3707, MC...

  12. 46 CFR 28.880 - Hydraulic equipment.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... times the system's maximum operating pressure. (c) Each hydraulic system must be equipped with at least... sudden loss of control due to loss of hydraulic system pressure. A system is considered to be fail-safe... catalog number and maximum allowable working pressure. (k) Existing hydraulic piping, nonmetallic hose...

  13. 46 CFR 28.880 - Hydraulic equipment.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... times the system's maximum operating pressure. (c) Each hydraulic system must be equipped with at least... sudden loss of control due to loss of hydraulic system pressure. A system is considered to be fail-safe... catalog number and maximum allowable working pressure. (k) Existing hydraulic piping, nonmetallic hose...

  14. 46 CFR 28.880 - Hydraulic equipment.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... times the system's maximum operating pressure. (c) Each hydraulic system must be equipped with at least... sudden loss of control due to loss of hydraulic system pressure. A system is considered to be fail-safe... catalog number and maximum allowable working pressure. (k) Existing hydraulic piping, nonmetallic hose...

  15. 46 CFR 28.880 - Hydraulic equipment.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... times the system's maximum operating pressure. (c) Each hydraulic system must be equipped with at least... sudden loss of control due to loss of hydraulic system pressure. A system is considered to be fail-safe... catalog number and maximum allowable working pressure. (k) Existing hydraulic piping, nonmetallic hose...

  16. Down with Remediation.

    ERIC Educational Resources Information Center

    Chaplin, Miriam T.

    1979-01-01

    Remedial education is contrary to traditional educational principles, for it operates only after a child has failed. Instead failure should be prevented by developmental, individualized instruction. Furthermore, remedial education isolates and emphasizes skill deficits and may lead to teaching for the test. (Author/SJL)

  17. Submucosal tunnel endoscopy: Peroral endoscopic myotomy and peroral endoscopic tumor resection

    PubMed Central

    Eleftheriadis, Nikolas; Inoue, Haruhiro; Ikeda, Haruo; Onimaru, Manabu; Maselli, Roberta; Santi, Grace

    2016-01-01

    Peroral endoscopic myotomy (POEM) is an innovative, minimally invasive, endoscopic treatment for esophageal achalasia and other esophageal motility disorders, emerged from the natural orifice transluminal endoscopic surgery procedures, and since the first human case performed by Inoue in 2008, showed exciting results in international level, with more than 4000 cases globally up to now. POEM showed superior characteristics than the standard 100-year-old surgical or laparoscopic Heller myotomy (LHM), not only for all types of esophageal achalasia [classical (I), vigorous (II), spastic (III), Chicago Classification], but also for advanced sigmoid type achalasia (S1 and S2), failed LHM, or other esophageal motility disorders (diffuse esophageal spasm, nutcracker esophagus or Jackhammer esophagus). POEM starts with a mucosal incision, followed by submucosal tunnel creation crossing the esophagogastric junction (EGJ) and myotomy. Finally the mucosal entry is closed with endoscopic clip placement. POEM permitted relatively free choice of myotomy length and localization. Although it is technically demanding procedure, POEM can be performed safely and achieves very good control of dysphagia and chest pain. Gastroesophageal reflux is the most common troublesome side effect, and is well controllable with proton pump inhibitors. Furthermore, POEM opened the era of submucosal tunnel endoscopy, with many other applications. Based on the same principles with POEM, in combination with new technological developments, such as endoscopic suturing, peroral endoscopic tumor resection (POET), is safely and effectively applied for challenging submucosal esophageal, EGJ and gastric cardia tumors (submucosal tumors), emerged from muscularis propria. POET showed up to know promising results, however, it is restricted to specialized centers. The present article reviews the recent data of POEM and POET and discussed controversial issues that need further study and future perspectives. PMID:26839649

  18. Safe and successful implementation of CPOE for chemotherapy at a children's cancer center.

    PubMed

    Hoffman, James M; Baker, Donald K; Howard, Scott C; Laver, Joseph H; Shenep, Jerry L

    2011-02-01

    Computerized prescriber order entry (CPOE) for medications has been implemented in only approximately 1 in 6 United States hospitals, with CPOE for chemotherapy lagging behind that for nonchemotherapy medications. The high risks associated with chemotherapy combined with other aspects of cancer care present unique challenges for the safe and appropriate use of CPOE. This article describes the process for safe and successful implementation of CPOE for chemotherapy at a children's cancer center. A core principle throughout the development and implementation of this system was that it must be as safe (and eventually safer) as existing paper systems and processes. The history of requiring standardized, regimen-specific, preprinted paper order forms served as the foundation for safe implementation of CPOE for chemotherapy. Extensive use of electronic order sets with advanced functionality; formal process redesign and system analysis; automated clinical decision support; and a phased implementation approach were essential strategies for safe implementation of CPOE. With careful planning and adequate resources, CPOE for chemotherapy can be safely implemented.

  19. Main propulsion system design recommendations for an advanced Orbit Transfer Vehicle

    NASA Technical Reports Server (NTRS)

    Redd, L.

    1985-01-01

    Various main propulsion system configurations of an advanced OTV are evaluated with respect to the probability of nonindependent failures, i.e., engine failures that disable the entire main propulsion system. Analysis of the life-cycle cost (LCC) indicates that LCC is sensitive to the main propulsion system reliability, vehicle dry weight, and propellant cost; it is relatively insensitive to the number of missions/overhaul, failures per mission, and EVA and IVA cost. In conclusion, two or three engines are recommended in view of their highest reliability, minimum life-cycle cost, and fail operational/fail safe capability.

  20. SoS Lablet; Perpetually Available and Secure Information Systems

    DTIC Science & Technology

    2015-11-16

    settings, people simply err on the safe side and do a lot less sharing, which explains why all pull -based location sharing applications have failed so...number of data centers is raising concerns about their power consumption. Through an NSF GOALI Bruce Krogh and I have investigated the problem by

  1. 75 FR 50878 - Airworthiness Directives; McDonnell Douglas Corporation Model MD-90-30 Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-18

    ... support fitting for the MLG failing during gear extension and subsequently damaging the hydraulic system... retract cylinder support fitting for the MLG, which could adversely affect the airplane's safe landing... service information identified in this AD, contact Boeing Commercial Airplanes, Attention: Data & Services...

  2. 14 CFR 23.775 - Windshields and windows.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... loadings and flight loads, or compliance with the fail-safe requirements of paragraph (d) of this section... loads combined with critical aerodynamic pressure and temperature effects, after failure of any load... in front of the pilots must be arranged so that, assuming the loss of vision through any one panel...

  3. 14 CFR 23.775 - Windshields and windows.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... loadings and flight loads, or compliance with the fail-safe requirements of paragraph (d) of this section... loads combined with critical aerodynamic pressure and temperature effects, after failure of any load... in front of the pilots must be arranged so that, assuming the loss of vision through any one panel...

  4. 14 CFR 23.775 - Windshields and windows.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... loadings and flight loads, or compliance with the fail-safe requirements of paragraph (d) of this section... loads combined with critical aerodynamic pressure and temperature effects, after failure of any load... in front of the pilots must be arranged so that, assuming the loss of vision through any one panel...

  5. 14 CFR 23.775 - Windshields and windows.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... loadings and flight loads, or compliance with the fail-safe requirements of paragraph (d) of this section... loads combined with critical aerodynamic pressure and temperature effects, after failure of any load... in front of the pilots must be arranged so that, assuming the loss of vision through any one panel...

  6. 14 CFR 23.775 - Windshields and windows.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... loadings and flight loads, or compliance with the fail-safe requirements of paragraph (d) of this section... loads combined with critical aerodynamic pressure and temperature effects, after failure of any load... in front of the pilots must be arranged so that, assuming the loss of vision through any one panel...

  7. 42 CFR 71.3 - Designation of yellow fever vaccination centers; Validation stamps.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... safe, potent, and pure yellow fever vaccine. Medical facilities of Federal agencies are authorized to obtain yellow fever vaccine without being designated as a yellow fever vaccination center by the Director..., storage, and administration of yellow fever vaccine. If a designated center fails to comply with such...

  8. Reading between the Lines

    ERIC Educational Resources Information Center

    Waters, John K.

    2009-01-01

    Biometrics has been making its way into school districts for the past decade. Biometric tools draw information from a person's identifying physical components, providing a virtually fail-safe level of protection for K-12 schools. In addition to their security uses, biometric systems are currently used in schools for cafeteria purchases, library…

  9. Is the Precautionary Principle Really Incoherent?

    PubMed

    Boyer-Kassem, Thomas

    2017-11-01

    The Precautionary Principle has been an increasingly important principle in international treaties since the 1980s. Through varying formulations, it states that when an activity can lead to a catastrophe for human health or the environment, measures should be taken to prevent it even if the cause-and-effect relationship is not fully established scientifically. The Precautionary Principle has been critically discussed from many sides. This article concentrates on a theoretical argument by Peterson (2006) according to which the Precautionary Principle is incoherent with other desiderata of rational decision making, and thus cannot be used as a decision rule that selects an action among several ones. I claim here that Peterson's argument fails to establish the incoherence of the Precautionary Principle, by attacking three of its premises. I argue (i) that Peterson's treatment of uncertainties lacks generality, (ii) that his Archimedian condition is problematic for incommensurability reasons, and (iii) that his explication of the Precautionary Principle is not adequate. This leads me to conjecture that the Precautionary Principle can be envisaged as a coherent decision rule, again. © 2017 Society for Risk Analysis.

  10. Beyond the Washington Consensus: Promoting Economic Growth and Minimizing the Threat of Violence in Latin America through Social Development

    DTIC Science & Technology

    2012-03-01

    International Economics, 1990). 3 Consensus principles .3 Finally, Rodrik fails to analyze the role of social spending and social development in both...Washington Consensus. Table 1 lists Rodrik’s economic first principles . 1. Protection of Property Rights 4. Appropriate Incentives 2. Contract...The Role of Macroeconomic Factors in Growth,” Journal of Monetary Economics 32, no. 3 (Dec. 1993): 485–512; Robert E. Lucas Jr., “Inflation and

  11. Flare system for safe disposal of LNG from a disabled tanker

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1982-12-01

    The feasibility of a flare system for the rapid and safe incineration of the cargo of a disabled LNG tanker is evaluated. The project developed design parameters and proof-of-principle investigations of a system for off-loading and flaring LNG from a disabled LNG tanker. The system described offers enough promise to warrant additional investigation, if cargo burning is desired as a way of reducing other possible hazards.

  12. [Fractographic analysis of clinically failed anterior all ceramic crowns].

    PubMed

    DU, Qian; Zhou, Min-bo; Zhang, Xin-ping; Zhao, Ke

    2012-04-01

    To identify the site of crack initiation and propagation path of clinically failed all ceramic crowns by fractographic analysis. Three clinically failed anterior IPS Empress II crowns and two anterior In-Ceram alumina crowns were retrieved. Fracture surfaces were examined using both optical stereo and scanning electron microscopy. Fractographic theory and fracture mechanics principles were applied to disclose the damage characteristics and fracture mode. All the crowns failed by cohesive failure within the veneer on the labial surface. Critical crack originated at the incisal contact area and propagated gingivally. Porosity was found within the veneer because of slurry preparation and the sintering of veneer powder. Cohesive failure within the veneer is the main failure mode of all ceramic crown. Veneer becomes vulnerable when flaws are present. To reduce the chances of chipping, multi-point occlusal contacts are recommended, and layering and sintering technique of veneering layer should also be improved.

  13. The principle of equivalence reconsidered: assessing the relevance of the principle of equivalence in prison medicine.

    PubMed

    Jotterand, Fabrice; Wangmo, Tenzin

    2014-01-01

    In this article we critically examine the principle of equivalence of care in prison medicine. First, we provide an overview of how the principle of equivalence is utilized in various national and international guidelines on health care provision to prisoners. Second, we outline some of the problems associated with its applications, and argue that the principle of equivalence should go beyond equivalence to access and include equivalence of outcomes. However, because of the particular context of the prison environment, third, we contend that the concept of "health" in equivalence of health outcomes needs conceptual clarity; otherwise, it fails to provide a threshold for healthy states among inmates. We accomplish this by examining common understandings of the concepts of health and disease. We conclude our article by showing why the conceptualization of diseases as clinical problems provides a helpful approach in the delivery of health care in prison.

  14. Safety considerations in the design and operation of large wind turbines

    NASA Technical Reports Server (NTRS)

    Reilly, D. H.

    1979-01-01

    The engineering and safety techniques used to assure the reliable and safe operation of large wind turbine generators utilizing the Mod 2 Wind Turbine System Program as an example is described. The techniques involve a careful definition of the wind turbine's natural and operating environments, use of proven structural design criteria and analysis techniques, an evaluation of potential failure modes and hazards, and use of a fail safe and redundant component engineering philosophy. The role of an effective quality assurance program, tailored to specific hardware criticality, and the checkout and validation program developed to assure system integrity are described.

  15. Antidepressants: Safe during Pregnancy?

    MedlinePlus

    ... healthy foods you and your baby need. Experiencing major depression during pregnancy is associated with an increased risk ... best chance for long-term health. Grigoriadis S. Unipolar major depression in pregnant women: General principles of treatment. https:// ...

  16. Living with vision loss

    MedlinePlus

    ... a white plate will stand out against a dark blue or dark green place mat. Handle Medicines Safely You should: ... to the principles of the Health on the Net Foundation (www.hon.ch). The information provided herein ...

  17. Quantum Cryptography II: How to re-use a one-time pad safely even if P=NP.

    PubMed

    Bennett, Charles H; Brassard, Gilles; Breidbart, Seth

    2014-01-01

    When elementary quantum systems, such as polarized photons, are used to transmit digital information, the uncertainty principle gives rise to novel cryptographic phenomena unachievable with traditional transmission media, e.g. a communications channel on which it is impossible in principle to eavesdrop without a high probability of being detected. With such a channel, a one-time pad can safely be reused many times as long as no eavesdrop is detected, and, planning ahead, part of the capacity of these uncompromised transmissions can be used to send fresh random bits with which to replace the one-time pad when an eavesdrop finally is detected. Unlike other schemes for stretching a one-time pad, this scheme does not depend on complexity-theoretic assumptions such as the difficulty of factoring.

  18. Enhancing future resilience in urban drainage system: Green versus grey infrastructure.

    PubMed

    Dong, Xin; Guo, Hao; Zeng, Siyu

    2017-11-01

    In recent years, the concept transition from fail-safe to safe-to-fail makes the application of resilience analysis popular in urban drainage systems (UDSs) with various implications and quantifications. However, most existing definitions of UDSs resilience are confined to the severity of flooding, while uncertainties from climate change and urbanization are not considered. In this research, we take into account the functional variety, topological complexity, and disturbance randomness of UDSs and define a new formula of resilience based on three parts of system severity, i.e. social severity affected by urban flooding, environmental severity caused by sewer overflow, and technological severity considering the safe operation of downstream facilities. A case study in Kunming, China is designed to compare the effect of green and grey infrastructure strategies on the enhancement of system resilience together with their costs. Different system configurations with green roofs, permeable pavement and storage tanks are compared by scenario analysis with full consideration of future uncertainties induced by urbanization and climate change. The research contributes to the development of sustainability assessment of urban drainage system with consideration of the resilience of green and grey infrastructure under future change. Finding the response measures with high adaptation across a variety of future scenarios is crucial to establish sustainable urban drainage system in a long term. Copyright © 2017. Published by Elsevier Ltd.

  19. Getting Beyond Yucca Mountain - 12305

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Halstead, Robert J.; Williams, James M.

    2012-07-01

    The U.S. Department of Energy has terminated the Yucca Mountain repository project. The U.S. Nuclear Regulatory Commission has indefinitely suspended the Yucca Mountain licensing proceeding. The presidentially-appointed Blue Ribbon Commission (BRC) on America's Nuclear Future is preparing a report, due in January 2012, to the Secretary of Energy on recommendations for a new national nuclear waste management and disposal program. The BRC Draft Report published in July 2011 provides a compelling critique of the past three decades failed efforts in the United States to site storage and disposal facilities for spent nuclear fuel (SNF) and high-level radioactive waste (HLW). However,more » the BRC Draft Report fails to provide detailed guidance on how to implement an alternative, successful approach to facility site selection. The comments submitted to the BRC by the State of Nevada Agency for Nuclear Projects provide useful details on how the US national nuclear waste program can get beyond the failed Yucca Mountain repository project. A detailed siting process, consisting of legislative elements, procedural elements, and 'rules' for volunteer sites, could meet the objectives of the BRC and the Western Governors Association (WGA), while promoting and protecting the interests of potential host states. The recent termination of the proposed Yucca Mountain repository provides both an opportunity and a need to re-examine the United States' nuclear waste management program. The BRC Draft Report published in July 2011 provides a compelling critique of the past three decades failed efforts in the United States to site storage and disposal facilities for SNF and HLW. It is anticipated that the BRC Final report in January 2012 will recommend a new general course of action, but there will likely continue to be a need for detailed guidance on how to implement an alternative, successful approach to facility site selection. Getting the nation's nuclear waste program back on track requires, among other things, new principles for siting-principles based on partnership between the federal implementing agency and prospective host states. These principles apply to the task of developing an integrated waste management strategy, to interactions between the federal government and prospective host states for consolidated storage and disposal facilities, and to the logistically and politically complicated task of transportation system design. Lessons from the past 25 years, in combination with fundamental parameters of the nuclear waste management task in the US, suggest new principles for partnership outlined in this paper. These principles will work better if well-grounded and firm guidelines are set out beforehand and if the challenge of maintaining competence, transparency and integrity in the new organization is treated as a problem to be addressed rather than a result to be expected. (authors)« less

  20. Genetic principles

    Treesearch

    Ronald P. Overton; David T. Funk

    1989-01-01

    Tree growth is a function of both environment and genetic makeup. All forest management activities during a rotation from establishment to harvest affect the genetic composition and the environment of a stand. Silvicultural practices which fail to take both of these factors into account will reduce forest productivity.

  1. Experimental Evidence for Diagramming Benefits in Science Writing

    ERIC Educational Resources Information Center

    Barstow, Brendan; Fazio, Lisa; Schunn, Christian; Ashley, Kevin

    2017-01-01

    Arguing for the need for a scientific research study (i.e. writing an introduction to a research paper) poses significant challenges for students. When faced with these challenges, students often generate overly safe replications (i.e. fail to find and include opposition to their hypothesis) or in contrast include no strong support for their…

  2. Power-Factor Controllers: How Safe?

    NASA Technical Reports Server (NTRS)

    Long, K.; Christian, W.; Kovacik, J.; Grazyk, T.

    1985-01-01

    Potential safety problems with power-factor controllers (PFC's) evaluated. Based on study of PFCs in use with appliances, report recommends measures to prevent consumers from misapplying these energy saving devices. Device used on such appliances as refrigerators, sewing machines, pumps, hair dryers, and food processors. When misused, they fail to save energy and may cause damage.

  3. 24 CFR 884.219 - Overcrowded and underoccupied units.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... assisted under this part is not Decent, Safe, and Sanitary by reason of increase in Family size, or that a Contract unit is larger than appropriate for the size of the Family in occupancy, housing assistance payments with respect to such unit will not be abated, unless the Owner fails to offer the Family a...

  4. Establishment of design criteria for acceptable failure modes and fail safe considerations for the space shuttle structural system

    NASA Technical Reports Server (NTRS)

    Westrup, R. W.

    1971-01-01

    The application of general design approaches for preventing failures due to repeated load cycles is briefly discussed. Program objective, mission requirements, and structural design criteria are summarized. Discrete structural elements and associated sections were selected for detailed strength, fatigue, and fracture mechanics investigations.

  5. Filter holder assembly having extended collar spacer ring

    DOEpatents

    Alvin, Mary Anne; Bruck, Gerald J.

    2002-01-01

    A filter holder assembly is provided that utilizes a fail-safe regenerator unit with an annular spacer ring having an extended metal collar for containment and positioning of a compliant ceramic gasket used in the assembly. The filter holder assembly is disclosed for use with advanced composite, filament wound, and metal candle filters.

  6. Keeping Schools Safe during Tight Budget Times

    ERIC Educational Resources Information Center

    Trump, Kenneth S.

    2010-01-01

    Tight budgets are no excuse for failing to be proactive with school safety. In fact, school leaders must be especially committed to prevention and security programs during times when economic woes are increasing stress on kids, their families and school staff. Parents will forgive educators if their school's test scores drop. But they are much…

  7. The Fail-Safe Micro Research Paper.

    ERIC Educational Resources Information Center

    Saunders, Mary Anne

    A key element in a research paper writing assignment modified for students of English as a second language to assure their success is teacher control over most of the process. A chronological plan for action for the micro research project includes these steps: creating an awareness of current events and controversial issues, practicing necessary…

  8. Accountable Game Design: Structuring the Dynamics of Student Learning Interactions

    ERIC Educational Resources Information Center

    Charoenying, Timothy

    2010-01-01

    Game-based classroom activity is intended to leverage students' interest and motivation to play, and to provide safe contexts for supporting students' academic learning. However, a basic criticism of many games currently used in classroom settings is that they can fail to meaningfully embody academic content. A more subtle concern is that…

  9. Active Fail-Safe Micro-Array Flow Control for Advanced Embedded Propulsion Systems

    NASA Technical Reports Server (NTRS)

    Anderson, Bernhard H.; Mace, James L.; Mani, Mori

    2009-01-01

    The primary objective of this research effort was to develop and analytically demonstrate enhanced first generation active "fail-safe" hybrid flow-control techniques to simultaneously manage the boundary layer on the vehicle fore-body and to control the secondary flow generated within modern serpentine or embedded inlet S-duct configurations. The enhanced first-generation technique focused on both micro-vanes and micro-ramps highly-integrated with micro -jets to provide nonlinear augmentation for the "strength' or effectiveness of highly-integrated flow control systems. The study focused on the micro -jet mass flow ratio (Wjet/Waip) range from 0.10 to 0.30 percent and jet total pressure ratios (Pjet/Po) from 1.0 to 3.0. The engine bleed airflow range under study represents about a 10 fold decrease in micro -jet airflow than previously required. Therefore, by pre-conditioning, or injecting a very small amount of high-pressure jet flow into the vortex generated by the micro-vane and/or micro-ramp, active flow control is achieved and substantial augmentation of the controlling flow is realized.

  10. Flow Structures and Interactions of a Fail-Safe Actuator

    NASA Astrophysics Data System (ADS)

    Khan, Wasif; Elimelech, Yoseph; Amitay, Michael

    2010-11-01

    Vortex generators are passive devices that are commonly used in many aerodynamic applications. In their basic concept, they enhance mixing, reduce or mitigate flow separation; however, they cause drag penalties at off design conditions. Micro vanes implement the same basic idea of vortex generators but their physical dimensions are much smaller. To achieve the same effect on the baseline flow field, micro vanes are combined with an active flow control device, so their net effect is comparable to that of vortex generators when the active device is energized. As a result of their small size, micro vanes have significantly less drag penalty at off design conditions. This concept of "dual-action" is the reason why such actuation is commonly called hybrid or fail-safe actuation. The present study explores experimentally the flow interaction of a synthetic-jet with a micro vane in a zero pressure gradient flow over a flat plate. Using the stereo particle image velocimetry technique a parametric study was conducted, where the effects of the micro vane shape, height and its angle with respect to the flow were examined, at several blowing ratios and synthetic-jet configurations.

  11. Folic acid and sulfasalazine for colorectal carcinoma chemoprevention in patients with ulcerative colitis: the old and new evidence.

    PubMed

    Diculescu, Mircea; Ciocîrlan, Mihai; Ciocîrlan, Mirela; Piţigoi, Dan; Becheanu, Gabriel; Croitoru, Adina; Spanache, Sandu

    2003-12-01

    The purpose of the study was to assess whether folic acid supplementation and long term therapy with sulfasalazine can reduce the risk of colorectal cancer (CRC) development in longstanding extensive ulcerative colitis. A meta-analysis was performed including the last 10 years published and Medline indexed studies on this subject. 3 studies have been included concerning the protective effect of folate supplementation in development of CRC. The association of these two factors is significant (effect size r =0.124, p = 0.025). The fail-safe number of studies with an opposite result should be 4 to revert the significance. 4 studies regarding sulfasalazine's protective effect in longstanding extensive ulcerative colitis have also been evaluated. A similar significance has been obtained, r = 0.148, p = 0.0007 and a fail-safe number of studies equal to 7. The homogeneity of these studies is validated by standard tests. Both sulfasalazine therapy and folate supplementation have a protective effect in colorectal cancer development in a population of patients with longstanding ulcerative colitis. Randomized controlled trials are needed to explore these hypotheses.

  12. EPR: Evidence and fallacy.

    PubMed

    Nichols, Joseph W; Bae, You Han

    2014-09-28

    The enhanced permeability and retention (EPR) of nanoparticles in tumors has long stood as one of the fundamental principles of cancer drug delivery, holding the promise of safe, simple and effective therapy. By allowing particles preferential access to tumors by virtue of size and longevity in circulation, EPR provided a neat rationale for the trend toward nano-sized drug carriers. Following the discovery of the phenomenon by Maeda in the mid-1980s, this rationale appeared to be well justified by the flood of evidence from preclinical studies and by the clinical success of Doxil. Clinical outcomes from nano-sized drug delivery systems, however, have indicated that EPR is not as reliable as previously thought. Drug carriers generally fail to provide superior efficacy to free drug systems when tested in clinical trials. A closer look reveals that EPR-dependent drug delivery is complicated by high tumor interstitial fluid pressure (IFP), irregular vascular distribution, and poor blood flow inside tumors. Furthermore, the animal tumor models used to study EPR differ from clinical tumors in several key aspects that seem to make EPR more pronounced than in human patients. On the basis of this evidence, we believe that EPR should only be invoked on a case-by-case basis, when clinical evidence suggests the tumor type is susceptible. Copyright © 2014 Elsevier B.V. All rights reserved.

  13. Dyslexic children fail to comply with the rhythmic constraints of handwriting.

    PubMed

    Pagliarini, Elena; Guasti, Maria Teresa; Toneatto, Carlo; Granocchio, Elisa; Riva, Federica; Sarti, Daniela; Molteni, Bruna; Stucchi, Natale

    2015-08-01

    In this study, we sought to demonstrate that deficits in a specific motor activity, handwriting, are associated to Developmental Dyslexia. The linguistic and writing performance of children with Developmental Dyslexia, with and without handwriting problems (dysgraphia), were compared to that of children with Typical Development. The quantitative kinematic variables of handwriting were collected by means of a digitizing tablet. The results showed that all children with Developmental Dyslexia wrote more slowly than those with Typical Development. Contrary to typically developing children, they also varied more in the time taken to write the individual letters of a word and failed to comply with the principles of isochrony and homothety. Moreover, a series of correlations was found among reading, language measures and writing measures suggesting that the two abilities may be linked. We propose that the link between handwriting and reading/language deficits is mediated by rhythm, as both reading (which is grounded on language) and handwriting are ruled by principles of rhythmic organization. Copyright © 2015 Elsevier B.V. All rights reserved.

  14. Advanced orbit transfer vehicle propulsion system study

    NASA Technical Reports Server (NTRS)

    Cathcart, J. A.; Cooper, T. W.; Corringrato, R. M.; Cronau, S. T.; Forgie, S. C.; Harder, M. J.; Mcallister, J. G.; Rudman, T. J.; Stoneback, V. W.

    1985-01-01

    A reuseable orbit transfer vehicle concept was defined and subsequent recommendations for the design criteria of an advanced LO2/LH2 engine were presented. The major characteristics of the vehicle preliminary design include a low lift to drag aerocapture capability, main propulsion system failure criteria of fail operational/fail safe, and either two main engines with an attitude control system for backup or three main engines to meet the failure criteria. A maintenance and servicing approach was also established for the advanced vehicle and engine concepts. Design tradeoff study conclusions were based on the consideration of reliability, performance, life cycle costs, and mission flexibility.

  15. A moral framework for multicultural education in healthcare.

    PubMed

    Vaught, Wayne

    2003-01-01

    The goal of this paper is two-fold. First, I begin by reviewing several of the major points of emphasis among health educators as they begin to incorporate multicultural issues into healthcare education. I then consider the role of moral relativism, which is currently being endorsed by some health educators, as the foundation for resolving cross-cultural conflicts in healthcare. I argue that moral relativism is ultimately inconsistent with the stated goals in multicultural curricular proposals and fails to provide an effective framework for considering moral conflicts in cross-cultural settings. Instead, I propose that those methods seeking to establish a common morality, built upon mutually shared values, offer the most promising means of resolving cross-cultural conflicts. This leads to my second goal, to compare recent work in moral pragmatism with what is now widely known in bioethics as moral "principlism." I argue that while proponents of principlism and pragmatism each seek to establish a common foundation for moral deliberation, they fail to appreciate significant similarities between their respective approaches. Instead of offering two completely unique and independent methods of moral deliberation, I suggest that principlism and pragmatism embrace common themes that point us in a positive direction, providing an effective framework useful for considering cross-cultural conflicts in healthcare.

  16. Analysis of older driver safety interventions : a human factors taxonomic approach

    DOT National Transportation Integrated Search

    1999-03-01

    The careful application of human factors design principles and guidelines is integral to : the development of safe, efficient and usable Intelligent Transportation Systems (ITS). One : segment of the driving population that may significantly benefit ...

  17. Playing It Safe: Part I.

    ERIC Educational Resources Information Center

    Penman, Kenneth A.; Niccolai, Frances R.

    1985-01-01

    The first of a series of articles explains the legal principles of tort liability, waiver of liability, comparative negligence, assumption of risk, and contributory negligence. Summarizes the kinds of cases going to court involving sport facility design and operation. (MLF)

  18. Teaching Conversation in the Second Language Classroom: Problems and Prospects.

    ERIC Educational Resources Information Center

    Sze, Paul

    1995-01-01

    Suggests principles and activities for the development of conversational competence in second-language learners. Shows that materials and activities traditionally used in language teaching fail to address the interactional dimension of conversation. Draws on conversational analysis, classroom discourse, and communicative competence to create a…

  19. Eliciting User Requirements Using Appreciative Inquiry

    ERIC Educational Resources Information Center

    Gonzales, Carol Kernitzki

    2010-01-01

    Many software development projects fail because they do not meet the needs of users, are over-budget, and abandoned. To address this problem, the user requirements elicitation process was modified based on principles of Appreciative Inquiry. Appreciative Inquiry, commonly used in organizational development, aims to build organizations, processes,…

  20. APOLLO COMMAND MODULE (CM) - SAFE TOUCHDOWN - PACIFIC OCEAN

    NASA Image and Video Library

    1971-08-07

    S71-41999 (7 Aug. 1971) --- The Apollo 15 Command Module (CM), with astronauts David R. Scott, commander; Alfred M. Worden, command module pilot; and James B. Irwin, lunar module pilot, aboard, nears a safe touchdown in the mid-Pacific Ocean to conclude a highly successful lunar landing mission. Although causing no harm to the crewmen, one of the three main parachutes failed to function properly. The splashdown occurred at 3:45:53 p.m. (CDT), Aug. 7, 1971, some 330 miles north of Honolulu, Hawaii. The three astronauts were picked up by helicopter and flown to the prime recovery ship USS Okinawa, which was only 6 1/2 miles away.

  1. Fail-safe transcription termination: Because one is never enough

    PubMed Central

    Lemay, Jean-François; Bachand, François

    2015-01-01

    Termination of RNA polymerase II (RNAPII) transcription is a fundamental step of gene expression that involves the release of the nascent transcript and dissociation of RNAPII from the DNA template. As transcription termination is intimately linked to RNA 3′ end processing, termination pathways have a key decisive influence on the fate of the transcribed RNA. Quite remarkably, when reaching the 3′ end of genes, a substantial fraction of RNAPII fail to terminate transcription, requiring the contribution of alternative or “fail-safe” mechanisms of termination to release the polymerase. This point of view covers redundant mechanisms of transcription termination and how they relate to conventional termination models. In particular, we expand on recent findings that propose a reverse torpedo model of termination, in which the 3′5′ exonucleolytic activity of the RNA exosome targets transcription events associated with paused and backtracked RNAPII. PMID:26273910

  2. The Presence of the Correlates of Effective Schools at the District Level: A Case Study

    ERIC Educational Resources Information Center

    Thompson, DeNelle

    2013-01-01

    Although the No Child Left Behind Act (NCLB) requires all American public schools to meet Adequate Yearly Progress (AYP), many fail to meet this standard each year. Effective Schools Research has revealed several correlates, such as a clear mission, a safe climate, strong instructional leadership, monitoring of student progress, strong…

  3. 28 CFR 90.106 - What are the grantee reporting requirements for the grant program?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... (CONTINUED) VIOLENCE AGAINST WOMEN Grants To Combat Violent Crimes Against Women on Campuses § 90.106 What..., Violence Against Women Office). Funding shall be suspended if a grantee fails to submit an annual..., Violence Against Women Office) and the Secretary of Education (U.S. Department of Education's Safe and Drug...

  4. Is the cervical spine clear? Undetected cervical fractures diagnosed only at autopsy.

    PubMed

    Sweeney, J F; Rosemurgy, A S; Gill, S; Albrink, M H

    1992-10-01

    Undetected cervical-spine injuries are a nemesis to both trauma surgeons and emergency physicians. Radiographic protocols have been developed to avoid missing cervical-spine fractures but are not fail-safe. Three case reports of occult cervical fractures documented at autopsy in the face of normal cervical-spine radiographs and computerized tomography scans are presented.

  5. 76 FR 28226 - Ndahendekire Barbara v. African Shipping; Njoroge Muhia; Alco Logistics, Llc; Brenda Alexander...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-16

    ... international cargo shipping; Respondent Njoroge Muhia is Chief Executive Officer for African Shipping... containers and chassis to Mombasa Kenya, violated Section 10(d)(1) of the Shipping Act, 46 U.S.C. 41102(c), by ``failing to ensure that Ms. Barbara[`s] (sic) container was delivered safely, securely and on...

  6. A Matter of Money? Policy Analysis of Rural Boarding Schools in China

    ERIC Educational Resources Information Center

    Zhao, Zhenzhou

    2011-01-01

    The Chinese government has shifted the pattern of rural schooling over the past decade, replacing village schools with urban boarding schools. The stated goal is to improve school quality, while deploying resources more effectively. However, the new boarding schools fail to provide a safe, healthy environment or protect and enable students' human…

  7. Battery Control Algorithms | Transportation Research | NREL

    Science.gov Websites

    publications. Accounting for Lithium-Ion Battery Degradation in Electric Vehicle Charging Optimization Advanced Reformulation of Lithium-Ion Battery Models for Enabling Electric Transportation Fail-Safe Design for Large Capacity Lithium-Ion Battery Systems Contact Ying Shi Email | 303-275-4240

  8. Rotating assembly working group summary

    NASA Technical Reports Server (NTRS)

    Kulkarni, S. V.

    1984-01-01

    The feasibility of a fail safe flywheel system was demonstrated. Three of the major advantages of flywheel systems are: longer operational life, higher electrical efficiency, and higher system energy density. The use of composite material flywheels is important to realize these advantages. Rotor design and dynamics, rotor materials and fabrication, safety, nondestructive testing, and systems operation loads and environment, are outlined.

  9. Fractographic analysis of anterior bilayered ceramic crowns that failed by veneer chipping.

    PubMed

    Du, Qian; Swain, Michael V; Zhao, Ke

    2014-05-01

    To fractographically analyze the reasons for the chipping of veneering porcelain in clinically failed anterior lithium disilicate glass-ceramic (LDG) and glass-infi ltrated alumina (GIA) crowns. Five anterior bilayered ceramic crowns with clinical veneer chipping failure were retrieved, of which three were LDG crowns and two were GIA crowns. The fractured surfaces of the failed restorations were examined using stereomicroscopy and scanning electron microscopy (SEM). The principles of fractography were used to identify the location and dimensions of the critical crack and to estimate the stress at failure. All five anterior crowns failed by cohesive failure within the veneer on the labial surface. Fractography showed that the critical crack initiated at the incisal contact area and propagated gingivally. The estimated stresses at failure for veneer chipping were lower than the characteristic strength of the veneer materials. Within the limitations of this in-vivo study, the contact damage, fatigue, and processing fl aws within the veneer are important reasons leading to chipping of veneering porcelain in anterior LDG and GIA crowns.

  10. Adult Cancer Pain

    PubMed Central

    Swarm, Robert A.; Abernethy, Amy Pickar; Anghelescu, Doralina L.; Benedetti, Costantino; Buga, Sorin; Cleeland, Charles; deLeon-Casasola, Oscar A.; Eilers, June G.; Ferrell, Betty; Green, Mark; Janjan, Nora A.; Kamdar, Mihir M.; Levy, Michael H.; Lynch, Maureen; McDowell, Rachel M.; Moryl, Natalie; Nesbit, Suzanne A.; Paice, Judith A.; Rabow, Michael W.; Syrjala, Karen L.; Urba, Susan G.; Weinstein, Sharon M.; Dwyer, Mary; Kumar, Rashmi

    2018-01-01

    Pain is a common symptom associated with cancer and its treatment. Pain management is an important aspect of oncologic care, and unrelieved pain significantly comprises overall quality of life. These NCCN Guidelines list the principles of management and acknowledge the range of complex decisions faced in the management oncologic pain. In addition to pain assessment techniques, these guidelines provide principles of use, dosing, management of adverse effects, and safe handling procedures of pharmacologic therapies and discuss a multidisciplinary approach for the management of cancer pain. PMID:23946177

  11. Application of a mathematical model for ergonomics in lean manufacturing.

    PubMed

    Botti, Lucia; Mora, Cristina; Regattieri, Alberto

    2017-10-01

    The data presented in this article are related to the research article "Integrating ergonomics and lean manufacturing principles in a hybrid assembly line" (Botti et al., 2017) [1]. The results refer to the application of the mathematical model for the design of lean processes in hybrid assembly lines, meeting both the lean principles and the ergonomic requirements for safe assembly work. Data show that the success of a lean strategy is possible when ergonomics of workers is a parameter of the assembly process design.

  12. Minimalism as a Guiding Principle: Linking Mathematical Learning to Everyday Knowledge

    ERIC Educational Resources Information Center

    Inoue, Noriyuki

    2008-01-01

    Studies report that students often fail to consider familiar aspects of reality in solving mathematical word problems. This study explored how different features of mathematical problems influence the way that undergraduate students employ realistic considerations in mathematical problem solving. Incorporating familiar contents in the word…

  13. A public utility model for managing public land recreation enterprises.

    Treesearch

    Tom Quinn

    2002-01-01

    Through review of relevant economic principles and judicial precedent, a case is made that public-land recreation enterprises are analogous to traditionally recognized public utilities. Given the historical concern over the societal value of recreation and associated pricing issues, public-land management policies failing to acknowledge these utility-like...

  14. Experimenting "Learn by Doing" and "Learn by Failing"

    ERIC Educational Resources Information Center

    Pozzi, Rossella; Noè, Carlo; Rossi, Tommaso

    2015-01-01

    According to the literature, in recent years, developing experiential learning has fulfilled the requirement of a deep understanding of lean philosophy by engineering students, demonstrating the advantages and disadvantages of some of the key principles of lean manufacturing. On the other hand, the literature evidences how some kinds of game-based…

  15. Development of Measures of Success for Corporate Level Air Force Acquisition Initiatives

    DTIC Science & Technology

    2004-03-01

    has failed. Customer satisfaction is described as the extent to which a process or product meets a customer’s expectations ( Kotler and Armstrong ...ADA366787). Kotler , P. and G. Armstrong . Principles of Marketing (9th Edition). Upper Saddle River NJ: Prentice Hall, 2001. Lambert, D. and T

  16. Modeling the Components of an Economy as a Complex Adaptive System

    DTIC Science & Technology

    principles of constrained optimization and fails to see economic variables as part of an interconnected network. While tools for forecasting economic...data sets such as the stock market . This research portrays the stock market as one component of a networked system of economic variables, with the

  17. Developing a Principled Framework for Materials Evaluation: Some Considerations

    ERIC Educational Resources Information Center

    Alkhaldi, Ali Ata

    2010-01-01

    Published language materials are widely used around the world, but many Foreign Language (FL) and/or Second Language (SL) learners still fail to develop their communicative competence satisfactorily and they are still not happy with their language materials. Materials design has recently been characterized by two important developments: first,…

  18. Sweet and Sustainable: Teaching the Biorefinery Concept through Biobased Gelator Synthesis

    ERIC Educational Resources Information Center

    Hwang, Hyeondo Luke; Jadhav, Swapnil Rohidas; Silverman, Julian Robert; John, George

    2014-01-01

    Undergraduate curricula have increasingly incorporated sustainable and environmentally friendly approaches in the laboratory. Learning outcomes have emphasized the importance of the principles of green chemistry, but experiments may fail to impress upon the students that large-scale conversions of biomass into a spectrum of value-added products…

  19. 49 CFR 383.95 - Restrictions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... applicant either fails the air brake component of the knowledge test, or performs the skills test in a... the skills test and the restriction, air brakes include any braking system operating fully or partially on the air brake principle. (b) Full air brake. (1) If an applicant performs the skills test in a...

  20. 29 CFR 553.227 - Outside employment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... such details and take disciplinary action against those who fail to do so. (e) Section 7(p)(1) applies... convention center during concerts or sports events. If the officers perform such work at their own option... overtime compensation. (f) The principles in paragraphs (d) and (e) of this section with respect to special...

  1. Failing by design.

    PubMed

    McGrath, Rita Gunther

    2011-04-01

    It's hardly news that business leaders work in increasingly uncertain environments, where failures are bound to be more common than successes. Yet if you ask executives how well, on a scale of one to 10, their organizations learn from failure, you'll often get a sheepish "Two-or maybe three" in response. Such organizations are missing a big opportunity: Failure may be inevitable but, if managed well, can be very useful. A certain amount of failure can help you keep your options open, find out what doesn't work, create the conditions to attract resources and attention, make room for new leaders, and develop intuition and skill. The key to reaping these benefits is to foster "intelligent failure" throughout your organization. McGrath describes several principles that can help you put intelligent failure to work. You should decide what success and failure would look like before you start a project. Document your initial assumptions, test and revise them as you go, and convert them into knowledge. Fail fast-the longer something takes, the less you'll learn-and fail cheaply, to contain your downside risk. Limit the number of uncertainties in new projects, and build a culture that tolerates, and sometimes even celebrates, failure. Finally, codify and share what you learn. These principles won't give you a means of avoiding all failures down the road-that's simply not realistic. They will help you use small losses to attain bigger wins over time.

  2. Against proportional shortfall as a priority-setting principle.

    PubMed

    Altmann, Samuel

    2018-05-01

    As the demand for healthcare rises, so does the need for priority setting in healthcare. In this paper, I consider a prominent priority-setting principle: proportional shortfall. My purpose is to argue that proportional shortfall, as a principle, should not be adopted. My key criticism is that proportional shortfall fails to consider past health.Proportional shortfall is justified as it supposedly balances concern for prospective health while still accounting for lifetime health, even though past health is deemed irrelevant. Accounting for this lifetime perspective means that the principle may indirectly consider past health by accounting for how far an individual is from achieving a complete, healthy life. I argue that proportional shortfall does not account for this lifetime perspective as it fails to incorporate the fair innings argument as originally claimed, undermining its purported justification.I go on to demonstrate that the case for ignoring past health is weak, and argue that past health is at least sometimes relevant for priority-setting decisions. Specifically, when an individual's past health has a direct impact on current or future health, and when one individual has enjoyed significantly more healthy life years than another.Finally, I demonstrate that by ignoring past illnesses, even those entirely unrelated to their current illness, proportional shortfall can lead to instances of double jeopardy, a highly problematic implication. These arguments give us reason to reject proportional shortfall. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  3. Does improved access to water supply by rural households enhance the concept of safe water at the point of use? A case study from deep rural South Africa.

    PubMed

    Jagals, P

    2006-01-01

    The concept of safe water is defined by three principles: the health-related quality must be suitable, the supply/source must be accessible and the water must constantly be available in quantities sufficient for the intended use. If any one (or more) of these three elements is missing from a water services improvement programme, providing safe water is not successfully achieved. A study in a deep rural area in South Africa showed that providing small communities, using untreated river water as their only water source, with good quality water through a piped distribution system and accessible at communal taps did not fall within our parameters of safe water. The parameters for measuring the three principles were: absence of Escherichia coli in drinking water samples; accessibility by improving tap distances to within 200 m from each household; availability by assessing whether households have at least 25 L per person per day. Results show that although E. coli levels were reduced significantly, households were still consuming water with E. coli numbers at non-compliant levels. Access (distance) was improved from an average of 750 m from households to river source to an average of 120 m to new on-tap source points. This did not result in significant increases in household quantities, which on average remained around 18 L per person per day.

  4. Evolution of the Hubble Space Telescope Safing Systems

    NASA Technical Reports Server (NTRS)

    Pepe, Joyce; Myslinski, Michael

    2006-01-01

    The Hubble Space Telescope (HST) was launched on April 24 1990, with an expected lifespan of 15 years. Central to the spacecraft design was the concept of a series of on-orbit shuttle servicing missions permitting astronauts to replace failed equipment, update the scientific instruments and keep the HST at the forefront of astronomical discoveries. One key to the success of the Hubble mission has been the robust Safing systems designed to monitor the performance of the observatory and to react to keep the spacecraft safe in the event of equipment anomaly. The spacecraft Safing System consists of a range of software tests in the primary flight computer that evaluate the performance of mission critical hardware, safe modes that are activated when the primary control mode is deemed inadequate for protecting the vehicle, and special actions that the computer can take to autonomously reconfigure critical hardware. The HST Safing System was structured to autonomously detect electrical power system, data management system, and pointing control system malfunctions and to configure the vehicle to ensure safe operation without ground intervention for up to 72 hours. There is also a dedicated safe mode computer that constantly monitors a keep-alive signal from the primary computer. If this signal stops, the safe mode computer shuts down the primary computer and takes over control of the vehicle, putting it into a safe, low-power configuration. The HST Safing system has continued to evolve as equipment has aged, as new hardware has been installed on the vehicle, and as the operation modes have matured during the mission. Along with the continual refinement of the limits used in the safing tests, several new tests have been added to the monitoring system, and new safe modes have been added to the flight software. This paper will focus on the evolution of the HST Safing System and Safing tests, and the importance of this evolution to prolonging the science operations of the telescope.

  5. Kool-Aid Chromatography

    ERIC Educational Resources Information Center

    Jenkins, Christie L.

    1986-01-01

    Offers guidelines and suggests activities that can introduce middle school students to the process and principles of chromatography in an inexpensive and safe manner. Proposes that experiences with Kool-aid and food coloring chromatography can provide insights into how scientists think, work, and communicate. (ML)

  6. WATER QUALITY IN SOURCE WATER, TREATMENT, AND DISTRIBUTION SYSTEMS

    EPA Science Inventory

    Most drinking water utilities practice the multiple-barrier concept as the guiding principle for providing safe water. This chapter discusses multiple barriers as they relate to the basic criteria for selecting and protecting source waters, including known and potential sources ...

  7. Semi-autonomous parking for enhanced safety and efficiency.

    DOT National Transportation Integrated Search

    2017-06-01

    This project focuses on the use of tools from a combination of computer vision and localization based navigation schemes to aid the process of efficient and safe parking of vehicles in high density parking spaces. The principles of collision avoidanc...

  8. Safe Patient Handling and Mobility: Development and Implementation of a Large-Scale Education Program.

    PubMed

    Lee, Corinne; Knight, Suzanne W; Smith, Sharon L; Nagle, Dorothy J; DeVries, Lori

    This article addresses the development, implementation, and evaluation of an education program for safe patient handling and mobility at a large academic medical center. The ultimate goal of the program was to increase safety during patient mobility/transfer and reduce nursing staff injury from lifting/pulling. This comprehensive program was designed on the basis of the principles of prework, application, and support at the point of care. A combination of online learning, demonstration, skill evaluation, and coaching at the point of care was used to achieve the goal. Specific roles and responsibilities were developed to facilitate implementation. It took 17 master trainers, 88 certified trainers, 176 unit-based trainers, and 98 coaches to put 3706 nurses and nursing assistants through the program. Evaluations indicated both an increase in knowledge about safe patient handling and an increased ability to safely mobilize patients. The challenge now is sustainability of safe patient-handling practices and the growth and development of trainers and coaches.

  9. Malpractice liability, technology choice and negative defensive medicine.

    PubMed

    Feess, Eberhard

    2012-04-01

    We extend the theoretical literature on the impact of malpractice liability by allowing for two treatment technologies, a safe and a risky one. The safe technology bears no failure risk, but leads to patient-specific disutility since it cannot completely solve the health problems. By contrast, the risky technology (for instance a surgery) may entirely cure patients, but fail with some probability depending on the hospital's care level. Tight malpractice liability increases care levels if the risky technology is chosen at all, but also leads to excessively high incentives for avoiding the liability exposure by adopting the safe technology. We refer to this distortion toward the safe technology as negative defensive medicine. Taking the problem of negative defensive medicine seriously, the second best optimal liability needs to balance between the over-incentive for the safe technology in case of tough liability and the incentive to adopt little care for the risky technology in case of weak liability. In a model with errors in court, we find that gross negligence where hospitals are held liable only for very low care levels outperforms standard negligence, even though standard negligence would implement the first best efficient care level.

  10. Fracture control methods for space vehicles. Volume 1: Fracture control design methods. [for space shuttle configuration planning

    NASA Technical Reports Server (NTRS)

    Liu, A. F.

    1974-01-01

    A systematic approach for applying methods for fracture control in the structural components of space vehicles consists of four major steps. The first step is to define the primary load-carrying structural elements and the type of load, environment, and design stress levels acting upon them. The second step is to identify the potential fracture-critical parts by means of a selection logic flow diagram. The third step is to evaluate the safe-life and fail-safe capabilities of the specified part. The last step in the sequence is to apply the control procedures that will prevent damage to the fracture-critical parts. The fracture control methods discussed include fatigue design and analysis methods, methods for preventing crack-like defects, fracture mechanics analysis methods, and nondestructive evaluation methods. An example problem is presented for evaluation of the safe-crack-growth capability of the space shuttle crew compartment skin structure.

  11. 26 CFR 1.121-3 - Reduced maximum exclusion for taxpayers failing to meet certain requirements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... by reason of a change in place of employment, health, or unforeseen circumstances. If a safe harbor described in this section applies, a sale or exchange is deemed to be by reason of a change in place of... sale or exchange is by reason of a change in place of employment, health, or unforeseen circumstances...

  12. 26 CFR 1.121-3 - Reduced maximum exclusion for taxpayers failing to meet certain requirements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... by reason of a change in place of employment, health, or unforeseen circumstances. If a safe harbor described in this section applies, a sale or exchange is deemed to be by reason of a change in place of... sale or exchange is by reason of a change in place of employment, health, or unforeseen circumstances...

  13. 26 CFR 1.121-3 - Reduced maximum exclusion for taxpayers failing to meet certain requirements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... by reason of a change in place of employment, health, or unforeseen circumstances. If a safe harbor described in this section applies, a sale or exchange is deemed to be by reason of a change in place of... sale or exchange is by reason of a change in place of employment, health, or unforeseen circumstances...

  14. 26 CFR 1.121-3 - Reduced maximum exclusion for taxpayers failing to meet certain requirements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... by reason of a change in place of employment, health, or unforeseen circumstances. If a safe harbor described in this section applies, a sale or exchange is deemed to be by reason of a change in place of... sale or exchange is by reason of a change in place of employment, health, or unforeseen circumstances...

  15. Toward A Fail-Safe Air Force Culture: Creating a Resilient Future While Avoiding Past Mistakes

    DTIC Science & Technology

    2012-10-01

    process often uses the “ Swiss cheese ” model to evaluate accidents. The image of holes in the protective cheese layers (proactive and reactive measures...minimize the number and size of holes in each slice of cheese . More importantly, however, a HRO’s 16 focus is on “the process of the slices lining up as

  16. Getting Comfortable with Failure and Vulnerability to Facilitate Learning and Innovation in the Game of School

    ERIC Educational Resources Information Center

    Machajewski, Szymon

    2017-01-01

    Schools are to prepare students for success. However, they often villainize failure. Instead, schools should teach students how to fail fast and safely in order to learn and to allow innovation through vulnerability. The lessons that the gaming culture has for learning will define future strategies of teaching and learning. Games are sometimes…

  17. 26 CFR 1.121-3 - Reduced maximum exclusion for taxpayers failing to meet certain requirements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... by reason of a change in place of employment, health, or unforeseen circumstances. If a safe harbor described in this section applies, a sale or exchange is deemed to be by reason of a change in place of... sale or exchange is by reason of a change in place of employment, health, or unforeseen circumstances...

  18. Securing Cyberspace: Approaches to Developing an Effective Cyber-Security Strategy

    DTIC Science & Technology

    2011-05-15

    attackers, cyber - criminals or even teenage hackers. Protecting cyberspace is a national security priority. President Obama’s National Security...prefers to engage international law enforcement to investigate and catch cyber criminals .40 International cooperation could resolve jurisdictional...sheltered them. Similarly, a state that fails to prosecute cyber - criminals , or who gives safe haven to individuals or groups that conduct cyber-attacks

  19. Snowmobiling in the 1980's: continued progress for a mature recreational activity

    Treesearch

    William T., Jr. Jobe

    1980-01-01

    In less than two decades, snowmobiling has changed from a novelty to a way of life for some 20,000,000 Canadian and American citizens of all ages. Why has snowmobiling continued to mushroom? Why did the challenges of inadequate safe use areas, public criticism and skepticism and primitive machines fail to doom the activity to a passing fad?

  20. Failing Safely: Increasing Theology and Religious Studies Students' Resilience and Academic Confidence via Risk-Taking in Formative Assessment

    ERIC Educational Resources Information Center

    Cornwall, Susannah

    2018-01-01

    Students increasingly appear anxious, risk-averse, and worried about getting things "wrong." They may appear to lack intellectual curiosity, and be unwilling to engage in independent study. This essay explores how teaching and assessment in theology and religious studies might help students learn to take intellectual risks, and increase…

  1. Electronic switches and control circuits: A compilation

    NASA Technical Reports Server (NTRS)

    1971-01-01

    The innovations in this updated series of compilations dealing with electronic technology represents a carefully selected collection of items on electronic switches and control circuits. Most of the items are based on well-known circuit design concepts that have been simplified or refined to meet NASA's demanding requirement for reliability, simplicity, fail-safe characteristics, and the capability of withstanding environmental extremes.

  2. Fail-Safe System against Potential Tumorigenicity after Transplantation of iPSC Derivatives.

    PubMed

    Itakura, Go; Kawabata, Soya; Ando, Miki; Nishiyama, Yuichiro; Sugai, Keiko; Ozaki, Masahiro; Iida, Tsuyoshi; Ookubo, Toshiki; Kojima, Kota; Kashiwagi, Rei; Yasutake, Kaori; Nakauchi, Hiromitsu; Miyoshi, Hiroyuki; Nagoshi, Narihito; Kohyama, Jun; Iwanami, Akio; Matsumoto, Morio; Nakamura, Masaya; Okano, Hideyuki

    2017-03-14

    Human induced pluripotent stem cells (iPSCs) are promising in regenerative medicine. However, the risks of teratoma formation and the overgrowth of the transplanted cells continue to be major hurdles that must be overcome. Here, we examined the efficacy of the inducible caspase-9 (iCaspase9) gene as a fail-safe against undesired tumorigenic transformation of iPSC-derived somatic cells. We used a lentiviral vector to transduce iCaspase9 into two iPSC lines and assessed its efficacy in vitro and in vivo. In vitro, the iCaspase9 system induced apoptosis in approximately 95% of both iPSCs and iPSC-derived neural stem/progenitor cells (iPSC-NS/PCs). To determine in vivo function, we transplanted iPSC-NS/PCs into the injured spinal cord of NOD/SCID mice. All transplanted cells whose mass effect was hindering motor function recovery were ablated upon transduction of iCaspase9. Our results suggest that the iCaspase9 system may serve as an important countermeasure against post-transplantation adverse events in stem cell transplant therapies. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  3. Comparison of three humidifiers during high-frequency percussive ventilation using the VDR-4® Fail-safe Breathing Circuit Hub.

    PubMed

    Tiffin, Norman H; Short, Kathy A; Jones, Samuel W; Cairns, Bruce A

    2011-01-01

    The VDR-4® high-frequency percussive ventilator (HFPV) has been shown to be beneficial in the management of inhalation injury by improving secretion clearance while maintaining oxygenation and ventilation. Delivery of gas flow during HFPV could lack adequate humidification delivered to the patient because a major portion of the delivered gas flow would bypass the humidifier when using the original VDR-4® ventilator circuit. The authors tested a novel inline vaporizing humidifier and two gas-water interface humidifiers during HFPV using the new VDR-4® Fail-safe Breathing Circuit Hub® to determine whether delivered humidification could be improved. This new humidification system, the Hydrate Omni™, delivers water vapor into the gas flow of the ventilator circuit rather than water droplets as delivered by the gas-water interface humidifiers. Measurements of absolute humidity and gas temperature were made on the three different humidification systems using a test lung model under standard ambient conditions. The authors found that when using the novel inline vaporizer, it provided better humidification when compared with the standard gas-water interface humidifier during HFPV using the new VDR-4® breathing circuit.

  4. The Joys of Liquid Nitrogen.

    ERIC Educational Resources Information Center

    Nolan, William T.; Gish, Thaddeus J.

    1996-01-01

    Presents 6 short experiments with liquid nitrogen that 12- and 13-year-old students can safely perform under close supervision. Helps the students in learning a number of basic chemical principles while spurring their curiosity and showing them how much fun chemistry can be. (JRH)

  5. Workstation Analysis, Ergonomic Style: Don't Despair, Teaching Ergonomic Workstation Analysis Isn't That Tough; but You Need a Plan.

    ERIC Educational Resources Information Center

    Merrell, Wayne L.; Zeimet, Denis E.

    1994-01-01

    Lists 15 principles for working safely with equipment. Describes phases of an ergonomic hazards program to identify and prevent problems and causes of cumulative trauma disorders in the workplace. (SK)

  6. Operational and safety efficiency of traffic signal installations.

    DOT National Transportation Integrated Search

    2008-05-01

    The basic principle of signalization is the provision of a safe and effective means for time and space allocation at an intersection for both vehicular and pedestrian needs. The safety community concurs on the fact that there is the potential for saf...

  7. Food safety training for nutritionists.

    PubMed Central

    Crowther, J. S.; Cox, L. J.; Gross, R.; Käferstein, F. A.

    1999-01-01

    A course on food safety for nutritionists has been developed in Indonesia through collaboration between government, industry, academia and international agencies. By teaching the basic principles of the subject it equips the participants to recommend foods that are safe as well as nutritious. PMID:10083718

  8. Detection and Prevention of Insider Threats in Database Driven Web Services

    NASA Astrophysics Data System (ADS)

    Chumash, Tzvi; Yao, Danfeng

    In this paper, we take the first step to address the gap between the security needs in outsourced hosting services and the protection provided in the current practice. We consider both insider and outsider attacks in the third-party web hosting scenarios. We present SafeWS, a modular solution that is inserted between server side scripts and databases in order to prevent and detect website hijacking and unauthorized access to stored data. To achieve the required security, SafeWS utilizes a combination of lightweight cryptographic integrity and encryption tools, software engineering techniques, and security data management principles. We also describe our implementation of SafeWS and its evaluation. The performance analysis of our prototype shows the overhead introduced by security verification is small. SafeWS will allow business owners to significantly reduce the security risks and vulnerabilities of outsourcing their sensitive customer data to third-party providers.

  9. Office procedures: practical and safety considerations.

    PubMed

    Erickson, Ty B

    2012-09-01

    Gynecologic invasive procedures have moved into the physician's office due to improved reimbursement and convenience. Creating a just and safe office culture has generated robust conversations in the medical literature. This article reviews the foundational principles relating to safe practices in the office including: checklists, drills, selecting a safety officer, achieving office certification, medication usage, and engaging the patient in the safety culture. Reduction of medical errors in the office will require open dialogue between the stake holders: providers, insurers, patients, state and federal agencies, and educational bodies such as the American College of Obstetricians and Gynecologists.

  10. [Study on standards for safe and health-protective zone in firework plant].

    PubMed

    Wu, Y; Wang, Q; Shi, J; Shao, Q

    1999-03-30

    A retrospective investigation on technology and situation in the production of fireworks, the cause and hazard consequences of accidents in blossom firework enterprises was carried out. The risk factors and their origins, the potential effects on surrounding environments and residents, the manufacture processes producing special potential energy in these enterprises were summarized and assessed. In addition, the consequences of explosive fire accidents were assessed retrospectively by the principle of explosion mechanics and Hopkinson Scaling Law. The safe and health-protective zone of the blossom firework plant was suggested.

  11. Safety in numbers 3: Authenticity, Building knowledge & skills and Competency development & assessment: the ABC of safe medication dosage calculation problem-solving pedagogy.

    PubMed

    Weeks, Keith W; Meriel Hutton, B; Coben, Diana; Clochesy, John M; Pontin, David

    2013-03-01

    When designing learning and assessment environments it is essential to articulate the underpinning education philosophy, theory, model and learning style support mechanisms that inform their structure and content. We elaborate on original PhD research that articulates the design rationale of authentic medication dosage calculation problem-solving (MDC-PS) learning and diagnostic assessment environments. These environments embody the principles of authenticity, building knowledge and skills and competency assessment and are designed to support development of competence and bridging of the theory-practice gap. Authentic learning and diagnostic assessment environments capture the features and expert practices that are located in real world practice cultures and recreate them in authentic virtual clinical environments. We explore how this provides students with a safe virtual authentic environment to actively experience, practice and undertake MDC-PS learning and assessment activities. We argue that this is integral to the construction and diagnostic assessment of schemata validity (mental constructions and frameworks that are an individual's internal representation of their world), bridging of the theory-practice gap and cognitive and functional competence development. We illustrate these principles through the underpinning pedagogical design of two online virtual authentic learning and diagnostic assessment environments (safeMedicate and eDose™). Copyright © 2012. Published by Elsevier Ltd.

  12. The design and implementation of on-line monitoring system for UHV compact shunt capacitors

    NASA Astrophysics Data System (ADS)

    Tao, Weiliang; Ni, Xuefeng; Lin, Hao; Jiang, Shengbao

    2017-08-01

    Because of the large capacity and compact structure of the UHV compact shunt capacitor, it is difficult to take effective measures to detect and prevent the faults. If the fault capacitor fails to take timely maintenance, it will pose a threat to the safe operation of the system and the life safety of the maintenance personnel. The development of UHV compact shunt capacitor on-line monitoring system can detect and record the on-line operation information of UHV compact shunt capacitors, analyze and evaluate the early fault warning signs, find out the fault capacitor or the capacitor with fault symptom, to ensure safe and reliable operation of the system.

  13. Holocamera for 3-D micrography of the alert human eye

    NASA Astrophysics Data System (ADS)

    Tokuda, A. R.; Auth, D. C.; Bruckner, A. P.

    1980-07-01

    A holocamera that safely records holograms of the full depth of the alert human eye with a spatial resolution of about 20 microns is described. A single-mode argon-ion laser generating 2 W at 5145 A serves as the illuminating source. Holographic exposure times of 0.3 msec are achieved by means of a fail-safe electromechanical shutter system. Integrated retinal irradiance levels are well under the American National Standards Institute safety standards. Reconstructed real images are projected directly onto the vidicon faceplate of a closed-circuit TV system, enabling convenient scanning in the x-y-z dimensions of the reconstructed eyeball. Serially reconstructed holograms of cataractous rabbit eyes and normal human eyes are presented.

  14. Safe and rapid resolution of severe hypertriglyceridaemia in two patients with intravenous insulin.

    PubMed

    Triay, J M; Day, A; Singhal, P

    2010-09-01

    To rapidly reduce serum triglyceride to a safe serum level. Severe hypertriglyceridaemia is associated with uncontrolled diabetes, obesity and poor physical activity. Even moderate increases in triglyceride levels (> 5mmol/L) confer an increased risk of pancreatitis and coronary artery disease. We present two patients with diabetes and serum triglyceride levels of greater than 85mmol/L despite polypharmacy intervention. 72-hour intravenous insulin infusion was administered. Serum triglyceride levels fell to 9.4 and 4.6 mmol/L respectively, without adverse events and sustained effect over several months. We suggest the use of intravenous insulin infusion where lifestyle and oral drug therapies have failed can impact on severe hypertriglyceridaemia.

  15. 75 FR 25887 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-10

    ... Generally Accepted Accounting Principles (GAAP). The Exchange also proposes to require firms that fail to... by Amendment No. 1, by NYSE Arca, Inc. Amending Rule 4, Capital Requirements, Financial Reports... Change The Exchange proposes to amend certain financial rules contained in Rule 4. A copy of this filing...

  16. Evaluation Responsibility and Leadership in the Face of Failing Democracies

    ERIC Educational Resources Information Center

    McKegg, Kate

    2013-01-01

    In a world faced with unprecedented rising levels of inequality and injustice, is there a responsibility for our evaluation organizations to take on a leadership role in promoting inclusive, evaluative dialog and deliberation about the state of our democracies in relation to key democratic principles and ideals? In this forum, I question whether…

  17. We Are, Therefore I Am: A Multisystems Approach with Families in Poverty.

    ERIC Educational Resources Information Center

    Brown, Shunda L.

    2002-01-01

    Although many individuals living in poverty are referred for family counseling services via schools, court systems, and social service agencies, theories have failed to provide an adequate framework for treatment. This article addresses the common principles of the multisystems approach and feminist family therapies and how they can be applied in…

  18. Interspecific hybridization in Pinus: a summary review

    Treesearch

    W.B. Critchfield

    1975-01-01

    The pines and other groups of temperate forest trees often fail to conform to widely accepted principles of plant evolution that are based primarily on observations of herbaceous plants. For example, interpreters of plant evolution tend to equate the fertility or sterility of inter specific hybrids with the magnitude of the genetically controlled reproductive barriers...

  19. "Fleshing Out Consensus": Radical Pragmatism, Civil Rights, and the Algebra Project

    ERIC Educational Resources Information Center

    Wahman, Jessica

    2009-01-01

    It has been said that pragmatism's "merely instrumental" truths fail to motivate radical change whereas absolute ideals make excellent guiding and driving forces for justice. However, in "Radical Equations: Math Literacy and Civil Rights," Robert Moses speaks of the radical success of pragmatic principles, used in the Civil Rights Movement, that…

  20. Game Engagement Theory and Adult Learning

    ERIC Educational Resources Information Center

    Whitton, Nicola

    2011-01-01

    One of the benefits of computer game-based learning is the ability of certain types of game to engage and motivate learners. However, theories of learning and engagement, particularly in the sphere of higher education, typically fail to consider gaming engagement theory. In this article, the author examines the principles of engagement from games…

  1. From Restaurants to Board Rooms: How Initiating Negotiations Teaches Management Principles and Theory

    ERIC Educational Resources Information Center

    Volkema, Roger J.; Kapoutsis, Ilias

    2016-01-01

    Negotiation is an interpersonal process common to everyday personal and professional success. Yet individuals often fail to recognize opportunities for initiating negotiations and the immediate and long-term implications of these oversights for themselves and others. This article describes a simple yet rich negotiation exercise that learners can…

  2. Venture Philanthropy's Market Strategies Fail Urban Kids

    ERIC Educational Resources Information Center

    Shiller, Jessica

    2012-01-01

    The latest wave of reform in urban schools, led by the venture philanthropists, has made a great deal of change, without much progress. Foundations with a venture philanthropy bent, like the Walton Family Foundation, the Gates Foundation, and the Broad Foundation, say market principles, such as choice and competition, will improve schools. If…

  3. Human Food Consumption: A Primer on Nonequilibrium Thermodynamics for College Physics

    ERIC Educational Resources Information Center

    Zurcher, Ulrich

    2008-01-01

    Students often have great difficulties with applications of the energy principle, especially those from biology, although most introductory physics texts include a brief discussion of metabolism. We point out that many of these discussions are unsatisfactory, since they often fail to mention how biological systems are "thermal systems in…

  4. Fracture mechanics and parapsychology

    NASA Astrophysics Data System (ADS)

    Cherepanov, G. P.

    2010-08-01

    The problem of postcritical deformation of materials beyond the ultimate strength is considered a division of fracture mechanics. A simple example is used to show the relationship between this problem and parapsychology, which studies phenomena and processes where the causality principle fails. It is shown that the concept of postcritical deformation leads to problems with no solution

  5. Corruption of Democratic Principles as a Source of Internal Conflict in Nigeria

    DTIC Science & Technology

    2012-11-02

    following examples demonstrate, the Nigerian government has failed miserably in meeting the intent of these constitutional articles. Two organizations...caused the value of the Nigerian Naira to fall from nearly $2 to les than $0.01. xix The literature is fairly clear that there is a very strong

  6. (abstract) The Design of a Benign Fail-safe Mechanism Using a Low-melting-point Metal Alloy Coupler

    NASA Technical Reports Server (NTRS)

    Blomquist, Richard S.

    1995-01-01

    Because the alpha proton X ray spectrometer (APXS) sensor head on the Mars Pathfinder rover, Sojourner, is placed on Martian soil by the deployment mechanism (ADM), the rover would be crippled if the actuator fails when the mechanism is in its deployed position, as rover ground clearance is then reduced to zero. This paper describes the unique fail-safe mounted on the ADM, especially the use of a low-temperature-melting alloy as a coupler device. The final form of the design is a low-melting-point metal pellet coupler, made from Cerrobend, in parallel with a Negator spring pack. In its solid state, the metal rigidly connects the driver (the actuator) and the driven part (the mechanism). When commanded, a strip heater wrapped around the coupler melts the metal pellet (at 60(deg)C), allowing the driven part to turn independent of the driver. The Negator spring retracts the mechanism to its fully stowed position. This concept meets all the design criteria, and provides an added benefit. When the metal hardens the coupler once again rigidly connects the actuator and the mechanism. The concept presented here can easily be applied to other applications. Anywhere release devices are needed, low-melting-point couplers can be considered. The issues to be concerned with are thermal isolation, proper setting of the parts before actuation, and possible outgassing concerns. However, when these issues are overcome, the resulting release mechanism can promise to be the most light, simple, power conserving alternative available.

  7. Non-contact optical Liquid Level Sensors

    NASA Astrophysics Data System (ADS)

    Kiseleva, L. L.; Tevelev, L. V.; Shaimukhametov, R. R.

    2016-06-01

    Information about characteristics of the optical liquid level sensor are present. Sensors are used to control of the light level limit fluid - water, kerosene, alcohol, solutions, etc. Intrinsically safe, reliable and easy to use. The operating principle of the level sensor is an optoelectronic infrared device.

  8. Aviation safety : information on FAA's data on operational errors at air traffic control towers

    DOT National Transportation Integrated Search

    2003-09-23

    A fundamental principle of aviation safety is the need to maintain adequate separation between aircraft and to ensure that aircraft maintain a safe distance from terrain, obstructions, and airspace that is not designated for routine air travel. Air t...

  9. Phosphate Removal and Recovery using Drinking Water Plant Waste Residuals

    EPA Science Inventory

    Water treatment plants are used to provide safe drinking water. In parallel, however, they also produce a wide variety of waste products which, in principle, could be possible candidates as resources for different applications. Calcium carbonate is one of such residual waste in ...

  10. Automated feedback to foster safe driving in young drivers : Phase 2.

    DOT National Transportation Integrated Search

    2015-12-01

    Intelligent Speed Adaptation (ISA) represents a promising approach to reduce speeding. A core principle for ISA systems is that they provide real-time feedback to drivers, prompting them to reduce speed when some threshold at or above the limit is re...

  11. Communication Speaks

    ERIC Educational Resources Information Center

    Kinman, Robin Lynn

    2010-01-01

    When the author recently turned her attention to the National Council of Teachers of Mathematics (NCTM) "Principles and Standards," she was startled to see communication as key. She adjusted her teaching to meet the NCTM Communication Standard and promote communication in her classroom by providing a safe environment, developing discourse and…

  12. Physiological closed-loop control in intelligent oxygen therapy: A review.

    PubMed

    Sanchez-Morillo, Daniel; Olaby, Osama; Fernandez-Granero, Miguel Angel; Leon-Jimenez, Antonio

    2017-07-01

    Oxygen therapy has become a standard care for the treatment of patients with chronic obstructive pulmonary disease and other hypoxemic chronic lung diseases. In current systems, manually continuous adjustment of O 2 flow rate is a time-consuming task, often unsuccessful, that requires experienced staff. The primary aim of this systematic review is to collate and report on the principles, algorithms and accuracy of autonomous physiological close-loop controlled oxygen devices as well to present recommendations for future research and studies in this area. A literature search was performed on medical database MEDLINE, engineering database IEEE-Xplore and wide-raging scientific databases Scopus and Web of Science. A narrative synthesis of the results was carried out. A summary of the findings of this review suggests that when compared to the conventional manual practice, the closed-loop controllers maintain higher saturation levels, spend less time below the target saturation, and save oxygen resources. Nonetheless, despite of their potential, autonomous oxygen therapy devices are scarce in real clinical applications. Robustness of control algorithms, fail-safe mechanisms, limited reliability of sensors, usability issues and the need for standardized evaluating methods of assessing risks can be among the reasons for this lack of matureness and need to be addressed before the wide spreading of a new generation of automatic oxygen devices. Copyright © 2017 Elsevier B.V. All rights reserved.

  13. In-simulator training of driving abilities in a person with a traumatic brain injury.

    PubMed

    Gamache, Pierre-Luc; Lavallière, Martin; Tremblay, Mathieu; Simoneau, Martin; Teasdale, Normand

    2011-01-01

    This study reports the case of a 23-year-old woman (MC) who sustained a severe traumatic brain injury in 2004. After her accident, her driving license was revoked. Despite recovering normal neuropsychological functions in the following years, MC was unable to renew her license, failing four on-road evaluations assessing her fitness to drive. In hope of an eventual license renewal, MC went through an in-simulator training programme in the laboratory in 2009. The training programme aimed at improving features of MC's driving behaviour that were identified as being problematic in prior on-road evaluations. To do so, proper driving behaviour was reinforced via driving-specific feedback provided during the training sessions. After 25 sessions in the simulator (over a period of 4 months), MC significantly improved various components of her driving. Notably, compared to early sessions, later ones were associated with a reduced cognitive load, less jerky speed profiles when stopping at intersections and better vehicle control and positioning. A 1-year retention test showed most of these improvements were consistent. The learning principles underlying well conducted simulator-based education programmes have a strong scientific basis. A simulator training programme like this one represents a promising avenue for driving rehabilitation. It allows individuals without a driving license to practice and improve their skills in a safe and realistic environment.

  14. A Synthetic-Biology-Inspired Therapeutic Strategy for Targeting and Treating Hepatogenous Diabetes.

    PubMed

    Xue, Shuai; Yin, Jianli; Shao, Jiawei; Yu, Yuanhuan; Yang, Linfeng; Wang, Yidan; Xie, Mingqi; Fussenegger, Martin; Ye, Haifeng

    2017-02-01

    Hepatogenous diabetes is a complex disease that is typified by the simultaneous presence of type 2 diabetes and many forms of liver disease. The chief pathogenic determinant in this pathophysiological network is insulin resistance (IR), an asymptomatic disease state in which impaired insulin signaling in target tissues initiates a variety of organ dysfunctions. However, pharmacotherapies targeting IR remain limited and are generally inapplicable for liver disease patients. Oleanolic acid (OA) is a plant-derived triterpenoid that is frequently used in Chinese medicine as a safe but slow-acting treatment in many liver disorders. Here, we utilized the congruent pharmacological activities of OA and glucagon-like-peptide 1 (GLP-1) in relieving IR and improving liver and pancreas functions and used a synthetic-biology-inspired design principle to engineer a therapeutic gene circuit that enables a concerted action of both drugs. In particular, OA-triggered short human GLP-1 (shGLP-1) expression in hepatogenous diabetic mice rapidly and simultaneously attenuated many disease-specific metabolic failures, whereas OA or shGLP-1 monotherapy failed to achieve corresponding therapeutic effects. Collectively, this work shows that rationally engineered synthetic gene circuits are capable of treating multifactorial diseases in a synergistic manner by multiplexing the targeting efficacies of single therapeutics. Copyright © 2017 The American Society of Gene and Cell Therapy. Published by Elsevier Inc. All rights reserved.

  15. Secure Embedded System Design Methodologies for Military Cryptographic Systems

    DTIC Science & Technology

    2016-03-31

    Fault- Tree Analysis (FTA); Built-In Self-Test (BIST) Introduction Secure access-control systems restrict operations to authorized users via methods...failures in the individual software/processor elements, the question of exactly how unlikely is difficult to answer. Fault- Tree Analysis (FTA) has a...Collins of Sandia National Laboratories for years of sharing his extensive knowledge of Fail-Safe Design Assurance and Fault- Tree Analysis

  16. Stress Corrosion of Ceramic Materials

    DTIC Science & Technology

    1981-10-01

    stresses are liable to fail after an indeterminate period of time, leading to a considerable uncertainty in the safe design stress. One of the objectives...of modern ceramics technology is to reduce the uncertainty associated with structural design , and hence, to improve our capabilities of designing ...processes that occur during stress corrosion cracking. Recent advances in th~earea of structural design with ceramic materials have lead to several

  17. Intranasal dexmedetomidine for sedation for pediatric computed tomography imaging.

    PubMed

    Mekitarian Filho, Eduardo; Robinson, Fay; de Carvalho, Werther Brunow; Gilio, Alfredo Elias; Mason, Keira P

    2015-05-01

    This prospective observational pilot study evaluated the aerosolized intranasal route for dexmedetomidine as a safe, effective, and efficient option for infant and pediatric sedation for computed tomography imaging. The mean time to sedation was 13.4 minutes, with excellent image quality, no failed sedations, or significant adverse events. Registered with ClinicalTrials.gov: NCT01900405. Copyright © 2015 Elsevier Inc. All rights reserved.

  18. Worcester 1 Inch Solenoid Actuated Gas Operated SCHe System Valves

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    VAN KATWIJK, C.

    1 inch Gas-operated full-port ball valves incorporate a solenoid and limit switches as integral parts of the actuator. These valves are normally open and fail safe to the open position (GOV-1*02 and 1*06 fall closed) to provide a flow path of helium gas to the MCO under helium purge and off-normal conditions when the MCO is isolated.

  19. Advanced manufacturing development of a composite empennage component for L-1011 aircraft. Phase 4: Full scale ground test

    NASA Technical Reports Server (NTRS)

    Jackson, A. C.; Dorwald, F.

    1982-01-01

    The ground tests conducted on the advanced composite vertical fin (ACVF) program are described. The design and fabrication of the test fixture and the transition structure, static test of Ground Test Article (GTA) No. 1, rework of GTA No. 2, and static, damage tolerance, fail-safe and residual strength tests of GTA No. 2 are described.

  20. Enhancing Students' Confidence in Employability Skills through the Practice of "Recall, Adapt and Apply"

    ERIC Educational Resources Information Center

    Sinclair, Alison J.

    2017-01-01

    The ability to apply prior knowledge to new challenges is a skill that is highly valued by employers, but the confidence to achieve this does not come naturally to all students. An essential step to becoming an independent researcher requires a transition between simply following a fail-safe set of instructions to being able to adapt a known…

  1. Adherence of Pharmaceutical Advertisements in Medical Journals to FDA Guidelines and Content for Safe Prescribing

    PubMed Central

    Korenstein, Deborah; Keyhani, Salomeh; Mendelson, Ali; Ross, Joseph S.

    2011-01-01

    Background Physician-directed pharmaceutical advertising is regulated in the United States by the Food and Drug Administration (FDA); adherence to current FDA guidelines is unknown. Our objective was to determine adherence rates of physician-directed print advertisements in biomedical journals to FDA guidelines and describe content important for safe prescribing. Methods and Findings Cross-sectional analysis of November 2008 pharmaceutical advertisements within top U.S.-based biomedical journals publishing original research. We excluded advertisements for devices, over the counter medications, and disease awareness. We utilized FDA guideline items identifying unique forms of advertisement bias to categorize advertisements as adherent to FDA guidelines, possibly non-adherent to at least 1 item, or non-adherent to at least 1 item. We also evaluated advertisement content important for safe prescribing, including benefit quantification, risk information and verifiable references. All advertisements were evaluated by 2 or more investigators, with differences resolved by discussion. Twelve journals met inclusion criteria. Nine contained pharmaceutical advertisements, including 192 advertisements for 82 unique products; median 2 per product (range 1–14). Six “teaser” advertisements presented only drug names, leaving 83 full unique advertisements. Fifteen advertisements (18.1%) adhered to all FDA guidelines, 41 (49.4%) were non-adherent with at least one form of FDA-described bias, and 27 (32.5%) were possibly non-adherent due to incomplete information. Content important for safe prescribing was often incomplete; 57.8% of advertisements did not quantify serious risks, 48.2% lacked verifiable references and 28.9% failed to present adequate efficacy quantification. Study limitations included its focus on advertisements from a single month, the subjectivity of FDA guidelines themselves, and the necessary subjectivity of determinations of adherence. Conclusions Few physician-directed print pharmaceutical advertisements adhere to all FDA guidelines; over half fail to quantify serious risks. The FDA could better protect public health by creating new more objective advertisement guidelines requiring transparent presentation of basic safety and efficacy information. PMID:21858076

  2. Adherence of pharmaceutical advertisements in medical journals to FDA guidelines and content for safe prescribing.

    PubMed

    Korenstein, Deborah; Keyhani, Salomeh; Mendelson, Ali; Ross, Joseph S

    2011-01-01

    Physician-directed pharmaceutical advertising is regulated in the United States by the Food and Drug Administration (FDA); adherence to current FDA guidelines is unknown. Our objective was to determine adherence rates of physician-directed print advertisements in biomedical journals to FDA guidelines and describe content important for safe prescribing. Cross-sectional analysis of November 2008 pharmaceutical advertisements within top U.S.-based biomedical journals publishing original research. We excluded advertisements for devices, over the counter medications, and disease awareness. We utilized FDA guideline items identifying unique forms of advertisement bias to categorize advertisements as adherent to FDA guidelines, possibly non-adherent to at least 1 item, or non-adherent to at least 1 item. We also evaluated advertisement content important for safe prescribing, including benefit quantification, risk information and verifiable references. All advertisements were evaluated by 2 or more investigators, with differences resolved by discussion. Twelve journals met inclusion criteria. Nine contained pharmaceutical advertisements, including 192 advertisements for 82 unique products; median 2 per product (range 1-14). Six "teaser" advertisements presented only drug names, leaving 83 full unique advertisements. Fifteen advertisements (18.1%) adhered to all FDA guidelines, 41 (49.4%) were non-adherent with at least one form of FDA-described bias, and 27 (32.5%) were possibly non-adherent due to incomplete information. Content important for safe prescribing was often incomplete; 57.8% of advertisements did not quantify serious risks, 48.2% lacked verifiable references and 28.9% failed to present adequate efficacy quantification. Study limitations included its focus on advertisements from a single month, the subjectivity of FDA guidelines themselves, and the necessary subjectivity of determinations of adherence. Few physician-directed print pharmaceutical advertisements adhere to all FDA guidelines; over half fail to quantify serious risks. The FDA could better protect public health by creating new more objective advertisement guidelines requiring transparent presentation of basic safety and efficacy information.

  3. The measure and significance of Bateman's principles

    PubMed Central

    Collet, Julie M.; Dean, Rebecca F.; Worley, Kirsty; Richardson, David S.; Pizzari, Tommaso

    2014-01-01

    Bateman's principles explain sex roles and sexual dimorphism through sex-specific variance in mating success, reproductive success and their relationships within sexes (Bateman gradients). Empirical tests of these principles, however, have come under intense scrutiny. Here, we experimentally show that in replicate groups of red junglefowl, Gallus gallus, mating and reproductive successes were more variable in males than in females, resulting in a steeper male Bateman gradient, consistent with Bateman's principles. However, we use novel quantitative techniques to reveal that current methods typically overestimate Bateman's principles because they (i) infer mating success indirectly from offspring parentage, and thus miss matings that fail to result in fertilization, and (ii) measure Bateman gradients through the univariate regression of reproductive over mating success, without considering the substantial influence of other components of male reproductive success, namely female fecundity and paternity share. We also find a significant female Bateman gradient but show that this likely emerges as spurious consequences of male preference for fecund females, emphasizing the need for experimental approaches to establish the causal relationship between reproductive and mating success. While providing qualitative support for Bateman's principles, our study demonstrates how current approaches can generate a misleading view of sex differences and roles. PMID:24648220

  4. An audience-channel-message-evaluation (ACME) framework for health communication campaigns.

    PubMed

    Noar, Seth M

    2012-07-01

    Recent reviews of the literature have indicated that a number of health communication campaigns continue to fail to adhere to principles of effective campaign design. The lack of an integrated, organizing framework for the design, implementation, and evaluation of health communication campaigns may contribute to this state of affairs. The current article introduces an audience-channel-message-evaluation (ACME) framework that organizes the major principles of health campaign design, implementation, and evaluation. ACME also explicates the relationships and linkages between the varying principles. Insights from ACME include the following: The choice of audience segment(s) to focus on in a campaign affects all other campaign design choices, including message strategy and channel/component options. Although channel selection influences options for message design, choice of message design also influences channel options. Evaluation should not be thought of as a separate activity, but rather should be infused and integrated throughout the campaign design and implementation process, including formative, process, and outcome evaluation activities. Overall, health communication campaigns that adhere to this integrated set of principles of effective campaign design will have a greater chance of success than those using principles idiosyncratically. These design, implementation, and evaluation principles are embodied in the ACME framework.

  5. Evolution of shuttle avionics redundancy management/fault tolerance

    NASA Technical Reports Server (NTRS)

    Boykin, J. C.; Thibodeau, J. R.; Schneider, H. E.

    1985-01-01

    The challenge of providing redundancy management (RM) and fault tolerance to meet the Shuttle Program requirements of fail operational/fail safe for the avionics systems was complicated by the critical program constraints of weight, cost, and schedule. The basic and sometimes false effectivity of less than pure RM designs is addressed. Evolution of the multiple input selection filter (the heart of the RM function) is discussed with emphasis on the subtle interactions of the flight control system that were found to be potentially catastrophic. Several other general RM development problems are discussed, with particular emphasis on the inertial measurement unit RM, indicative of the complexity of managing that three string system and its critical interfaces with the guidance and control systems.

  6. Safe-trajectory optimization and tracking control in ultra-close proximity to a failed satellite

    NASA Astrophysics Data System (ADS)

    Zhang, Jingrui; Chu, Xiaoyu; Zhang, Yao; Hu, Quan; Zhai, Guang; Li, Yanyan

    2018-03-01

    This paper presents a trajectory-optimization method for a chaser spacecraft operating in ultra-close proximity to a failed satellite. Based on the combination of active and passive trajectory protection, the constraints in the optimization framework are formulated for collision avoidance and successful docking in the presence of any thruster failure. The constraints are then handled by an adaptive Gauss pseudospectral method, in which the dynamic residuals are used as the metric to determine the distribution of collocation points. A finite-time feedback control is further employed in tracking the optimized trajectory. In particular, the stability and convergence of the controller are proved. Numerical results are given to demonstrate the effectiveness of the proposed methods.

  7. A Rejection Principle for Sequential Tests of Multiple Hypotheses Controlling Familywise Error Rates

    PubMed Central

    BARTROFF, JAY; SONG, JINLIN

    2015-01-01

    We present a unifying approach to multiple testing procedures for sequential (or streaming) data by giving sufficient conditions for a sequential multiple testing procedure to control the familywise error rate (FWER). Together we call these conditions a “rejection principle for sequential tests,” which we then apply to some existing sequential multiple testing procedures to give simplified understanding of their FWER control. Next the principle is applied to derive two new sequential multiple testing procedures with provable FWER control, one for testing hypotheses in order and another for closed testing. Examples of these new procedures are given by applying them to a chromosome aberration data set and to finding the maximum safe dose of a treatment. PMID:26985125

  8. Transarterial Onyx Embolization for Patients with Cavernous Sinus Dural Arteriovenous Fistulas Who Have Failed Transvenous Embolization.

    PubMed

    Wen, Jun; Duan, Chuan-Zhi; Huang, Li-Jing; Zhang, Xin; He, Xu-Ying; Li, Xi-Feng

    2015-09-01

    Transvenous embolization is the treatment of choice for cavernous sinus dural arteriovenous fistulas (csDAVFs) despite occasional difficulty in transvenous catheterization. We reported our experience in the treatment of csDAVFs by transarterial Onyx embolization in patients who had failed transvenous catheterization. We reviewed the clinical and radiographic records of csDAVFs patients receiving transarterial Onyx embolization after failed transvenous Onyx embolization at our institution over a period of 31 months. Success was defined as complete or near complete occlusion upon angiographic examination. In seven cases, the microcatheter failed to reach the cavernous sinus; in the remaining case, the internal jugular vein was occlusive. Eight sessions of the embolization and catheterization procedures via the arterial routes were conducted. Among them, five cases via the middle meningeal artery and the other three via the accessory meningeal artery. Angiography, immediately after embolization, revealed complete occlusion in seven cases (87.5 %) and partial occlusion in the remaining case. Angiographic follow-up (range, 6-10 months) showed that all patients achieved complete embolization. In cases where transvenous embolization of the cavernous sinus is difficult, transarterial embolization of the fistulas offers a safe and effective alternative.

  9. Aquatic Exercise for the Aged.

    ERIC Educational Resources Information Center

    Daniel, Michael; And Others

    The development and implementation of aquatic exercise programs for the aged are discussed in this paper. Program development includes a discussion of training principles, exercise leadership and the setting up of safe water exercise programs for the participants. The advantages of developing water exercise programs and not swimming programs are…

  10. El control biologico de plagas(Biological control of pests)

    USDA-ARS?s Scientific Manuscript database

    In this work some ecological principles that drive applied biocontrol and agent selection are discussed. Subjects such as specificity evaluations, host shifts and species invasiveness are analyzed under the light of ecological theory. The main assertions are: 1. biological control is a safe and bene...

  11. Automated feedback to foster safe driving in young drivers: phase 2 : traffic tech.

    DOT National Transportation Integrated Search

    2015-12-01

    Intelligent Speed Adaptation (ISA) provides a promising approach to reduce speeding. A core principle of ISA is real-time feedback that lets drivers know when they are driving over the speed limit. The overall goal of the study was to provide insight...

  12. Resistance Training for Elementary School Age Children

    ERIC Educational Resources Information Center

    Langford, George A.; McCurdy, Kevin W.

    2005-01-01

    It is essential for physical education teachers to utilize a foundation of physiological principles to design and monitor appropriate, safe, and effective exercise for their students. Adult training programs are not appropriate for children. Teachers should consider individual levels of maturation, motor skill ability, and affective needs when…

  13. Prudent Practices for Handling Hazardous Chemicals in Laboratories.

    ERIC Educational Resources Information Center

    National Academy of Sciences-National Research Council, Washington, DC. Assembly of Mathematical and Physical Sciences.

    This guide recommends procedures for safe handling and disposal of hazardous substances, along with broad recommendations for developing comprehensive laboratory safety programs. Although specific information is provided, general principles which can be adapted to activities in any laboratory are emphasized. Section 1 focuses on procedures for…

  14. Effects of the High School Economics Curriculum on Learning in the College Principles Class.

    ERIC Educational Resources Information Center

    Lopus, Jane S.

    1997-01-01

    Asserts that most research into the effects of high school economics curriculum upon performance in college level economics courses fails to consider that secondary economics education rarely teaches micro- and macroeconomic concepts. Discovers that any gap in learning between students in economics is narrowed by the first semester in college.…

  15. When Mergers Fail: A Case Study on the Critical Role of External Stakeholders in Merger Initiatives

    ERIC Educational Resources Information Center

    Stensaker, Bjørn; Persson, Mats; Pinheiro, Rómulo

    2016-01-01

    One can, in principle, identify numerous arguments for mergers in higher education (HE), including efficiency, diversity, quality, and regional needs. This diversity can be explained by the growing societal interest in the sector, not least concerning the contributions from HE to society at large. However, research on merger processes has tended…

  16. Enriching Students' Education Using Interactive Workstations at a Salt Mine Turned Science Center

    ERIC Educational Resources Information Center

    Meissner, Barbara; Bogner, Franz

    2011-01-01

    Although teachers in principle are prepared to make use of science centers, such excursions often fail to facilitate learning processes. Therefore, it is necessary to improve the link between science centers and schools. The design and evaluation of valuable outreach projects may enhance students' out-of-school science learning. In our study, we…

  17. High Performance Education Fails in Sustainability?--A Reflection on Finnish Primary Teacher Education

    ERIC Educational Resources Information Center

    Wolff, Lili-Ann; Sjöblom, Pia; Hofman-Bergholm, Maria; Palmberg, Irmeli

    2017-01-01

    Sustainability is internationally often emphasized as an essential aim of higher education, but more as a principle than on the practical level. This is also obvious in the academic education of primary teachers in Finland. Therefore, it is a great challenge for Finnish teachers to include sustainability in their teaching and everyday life in…

  18. Redefining the "Public": Neoliberalism and the Corporate Appropriation of Public Education in Los Angeles

    ERIC Educational Resources Information Center

    Tate, Eliza

    2017-01-01

    This study examines how the discourse of the crisis and failing of public education creates space for the legitimization and deployment of neoliberal logic of education reform based on free market principles specifically in Los Angeles. It utilizes Critical Discourse Analysis to examine how these discourses and logic of neoliberal reform are…

  19. The Use and Effectiveness of a Targeted Math Intervention for Third Graders

    ERIC Educational Resources Information Center

    Pool, Juli L.; Carter, Gabriel M.; Johnson, Evelyn S.; Carter, Deborah R.

    2013-01-01

    Students who fail to develop proficiency in math skills in the primary grades are more likely to experience difficulties in the math curriculum later on. These students may be in need of a more targeted intervention, or Tier 2 supports, in mathematic instruction. Although the instructional principles of an effective math intervention are becoming…

  20. Lingering Problems of Currency and Scope in Daniels's Argument for a Societal Obligation to Meet Health Needs

    PubMed Central

    Sachs, Benjamin

    2010-01-01

    Norman Daniels's new book, Just Health, brings together his decades of work on the problem of justice and health. It improves on earlier writings by discussing how we can meet health needs fairly when we cannot meet them all and by attending to the implications of the socioeconomic determinants of health. In this article I return to the core idea around which the entire theory is built: that the principle of equality of opportunity grounds a societal obligation to meet health needs. I point, first, that nowhere does Daniels say just what version of that principle he accepts. I then proceed to construct a principle on his behalf, based on a faithful reading of Just Health. Once we actually nail down the principle, I argue, we will find that there are two problems: it is implausible in itself, and it fails to ground a societal obligation to meet health needs. PMID:20634271

  1. Rethinking infant knowledge: toward an adaptive process account of successes and failures in object permanence tasks.

    PubMed

    Munakata, Y; McClelland, J L; Johnson, M H; Siegler, R S

    1997-10-01

    Infants seem sensitive to hidden objects in habituation tasks at 3.5 months but fail to retrieve hidden objects until 8 months. The authors first consider principle-based accounts of these successes and failures, in which early successes imply knowledge of principles and failures are attributed to ancillary deficits. One account is that infants younger than 8 months have the object permanence principle but lack means-ends abilities. To test this, 7-month-olds were trained on means-ends behaviors and were tested on retrieval of visible and occluded toys. Means-ends demands were the same, yet infants made more toy-guided retrievals in the visible case. The authors offer an adaptive process account in which knowledge is graded and embedded in specific behavioral processes. Simulation models that learn gradually to represent occluded objects show how this approach can account for success and failure in object permanence tasks without assuming principles and ancillary deficits.

  2. The value of life in English law: revered but not sacred?

    PubMed

    Heywood, Rob; Mullock, Alexandra

    2016-12-01

    Terms such as sanctity and inviolability have failed to provide a legally coherent or ethically sound principle upon which to determine the scope of the intrinsic value of life against extrinsic , quality-of-life considerations in a medical context . In their recent work , Margaret Brazier and Suzanne Ost introduce a new term , reverence for life, which they suggest may be more appropriate when attempting to navigate the murky waters of the meaning of life and the value that should be attached to it . They suggest that reverence should be utilised as an alternative that better reflects the nuances and the realities of the dilemma . This paper explores the existing difficulties before considering how the principle of reverence might provide a principled compromise over when the presumption in favour of preserving life should be rebutted .

  3. Diagnosis: Reasoning from first principles and experiential knowledge

    NASA Technical Reports Server (NTRS)

    Williams, Linda J. F.; Lawler, Dennis G.

    1987-01-01

    Completeness, efficiency and autonomy are requirements for suture diagnostic reasoning systems. Methods for automating diagnostic reasoning systems include diagnosis from first principles (i.e., reasoning from a thorough description of structure and behavior) and diagnosis from experiential knowledge (i.e., reasoning from a set of examples obtained from experts). However, implementation of either as a single reasoning method fails to meet these requirements. The approach of combining reasoning from first principles and reasoning from experiential knowledge does address the requirements discussed above and can possibly ease some of the difficulties associated with knowledge acquisition by allowing developers to systematically enumerate a portion of the knowledge necessary to build the diagnosis program. The ability to enumerate knowledge systematically facilitates defining the program's scope, completeness, and competence and assists in bounding, controlling, and guiding the knowledge acquisition process.

  4. Vaccination in the primary care setting: when is it safe to proceed?

    PubMed

    Ngoh, Hui Lee Sharon; Ng, Mark Chung Wai

    2016-01-01

    Primary care practitioners play an important role in administering and advocating vaccinations against vaccine-preventable infectious diseases and ensuring herd immunity in our population. This is a follow-up article to an earlier one which dealt with the principles of vaccine scheduling and administration. This article describes several false contraindications to vaccination that a primary care practitioner may encounter, including pregnancy, current breastfeeding, history of febrile seizures, and having immunosuppressed or pregnant household contacts. We aimed to provide a guide for safe and timely vaccine administration in the primary care setting. Copyright © Singapore Medical Association.

  5. Perforated Sigmoid Diverticular Disease: a Management Protocol

    PubMed Central

    Moin, Thajammul

    2008-01-01

    Background: To develop an evidence-based protocol for the management of perforated sigmoid diverticular disease. Methods: A search of the literature was undertaken. All publications pertaining to perforated sigmoid diverticular disease were analyzed and then categorized according to their level of evidence. Recommendations were then made on the basis of this. Results: Multiple case reports suggest that primary closure of perforation of sigmoid diverticula is safe in the absence of peritoneal contamination. Conclusions: A 2-stage laparoscopic approach incorporating the principles of damage limitation surgery may be a safe strategy in the management of perforated diverticular disease. PMID:18435896

  6. Management of post-traumatic elbow instability after failed radial head excision: A case report.

    PubMed

    Touloupakis, Georgios; Theodorakis, Emmanouil; Favetti, Fabio; Nannerini, Massimiliano

    2017-02-01

    Radial head excision has always been a safe commonly used surgical procedure with a satisfactory clinical outcome for isolated comminuted radial head fractures. However, diagnosis of elbow instability is still very challenging and often underestimated in routine orthopaedic evaluation. We present the case of a 21-years old female treated with excision after radial head fracture, resulting in elbow instability. The patient underwent revision surgery after four weeks. We believe that ligament reconstruction without radial head substitution is a safe alternative choice for Mason III radial head fractures accompanied by complex ligament lesions. Copyright © 2017 Daping Hospital and the Research Institute of Surgery of the Third Military Medical University. Production and hosting by Elsevier B.V. All rights reserved.

  7. Wilderness Medicine: Considerations of Adventure Travel in Tropical Areas of Latin America.

    ERIC Educational Resources Information Center

    Cochran, Brent

    Adventure travel to Latin America requires careful planning, implementation, and followup to ensure safe, healthy experiences. This paper provides an overview of basic principles of prevention, assessment, and treatment of medical problems common to adventure travel in tropical areas. A brief introduction defines the vegetation and climatic…

  8. Building a model-based decision support system for solving vehicle routing and driver scheduling problems under hours of service regulations.

    DOT National Transportation Integrated Search

    2011-08-27

    "In principle, hours-of-service (HOS) regulations are intended to help truck drivers ensure get adequate rest and perform safe operations. The new HOS regulations, however, may lead to substantial cost increases for regional common carriers which hav...

  9. Understanding and Dealing with Bullying in Schools

    ERIC Educational Resources Information Center

    Yerger, William; Gehret, Cliff

    2011-01-01

    One of the most difficult problems that educators face today is dealing with bullying. This pervasive issue occurs in classrooms, lunch rooms, unsupervised areas, on playgrounds, and through electronic media. Based on the principles of protecting the child and establishing a safe environment for all students, this paper investigates the causes and…

  10. The role of low impact herbicide treatments in ecosystem management

    Treesearch

    Charles K. McMahon; James H. Miller; David F. Thomas

    1994-01-01

    Abstract. Environmentally safe, selective herbicide treatments can be adapted to manage habitats and direct succession toward desired future conditions within the principles of ecosystem 0. Six roles for herbicide treatments in ecosystem management are suggested: create and maintain desired habitats; create mixed and uneven-aged stands; restore...

  11. Anaesthesia at the District Hospital. Second Edition.

    ERIC Educational Resources Information Center

    Dobson, Michael B.

    This practical manual is designed to help medical officers in small hospitals provide safe and effective anesthesia for patients. Intended for doctors with at least one year of postgraduate clinical experience, it describes anesthetic techniques suitable for use in hospitals with limited resources. Chapter 2 describes fundamental principles and…

  12. Balloon logging with the inverted skyline

    NASA Technical Reports Server (NTRS)

    Mosher, C. F.

    1975-01-01

    There is a gap in aerial logging techniques that has to be filled. The need for a simple, safe, sizeable system has to be developed before aerial logging will become effective and accepted in the logging industry. This paper presents such a system designed on simple principles with realistic cost and ecological benefits.

  13. Handbook for Driving Knowledge Testing.

    ERIC Educational Resources Information Center

    Pollock, William T.; McDole, Thomas L.

    Materials intended for driving knowledge test development for use by operational licensing and education agencies are presented. A pool of 1,313 multiple choice test items is included, consisting of sets of specially developed and tested items covering principles of safe driving, legal regulations, and traffic control device knowledge pertinent to…

  14. Development of a National Item Bank for Tests of Driving Knowledge.

    ERIC Educational Resources Information Center

    Pollock, William T.; McDole, Thomas L.

    Materials intended for driving knowledge test development use by operational licensing and education agencies were prepared. Candidate test items were developed, using literature and operational practice sources, to reflect current state-of-knowledge with respect to principles of safe, efficient driving, to legal regulations, and to traffic…

  15. 45 CFR 1355.25 - Principles of child and family services.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... DEVELOPMENT SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION ON CHILDREN, YOUTH AND... development of children. One important way to keep children safe is to stop violence in the family including... functioning and well-being. (c) Services promote the healthy development of children and youth, promote...

  16. A Guide for the Safe Handling of Engineered and Fabricated Nanomaterials

    ERIC Educational Resources Information Center

    Greaves-Holmes, Wanda L.

    2009-01-01

    In the absence of scientific clarity regarding the potential health effects of occupational exposure to nanoparticles, there is a need for guidance in making decisions about hazards, risks, and controls (Schulte & Salmanca-Buentello, 2007). Presently, no guiding principles have been universally accepted for personal protective equipment that is…

  17. Have a Blast, Safely!

    ERIC Educational Resources Information Center

    Roy, Ken

    2005-01-01

    Model rocketry is one of the best ways to get students interested in the physical sciences. Following safety guidelines, rocketry can really turn students on to science and also help them understand the applications of theories and scientific principles (Newton's laws of motion, force, mass, projectile motion, etc.) they are learning. The study…

  18. Restraint and Seclusion: Resource Document

    ERIC Educational Resources Information Center

    US Department of Education, 2012

    2012-01-01

    The first responsibility of education leaders must be to ensure that schools foster learning in a safe and healthy environment for all of our children, teachers, and staff. To support schools in fulfilling that responsibility, the U.S. Department of Education has developed this document that describes 15 principles for States, school districts,…

  19. Techniques for Managing a Safe School.

    ERIC Educational Resources Information Center

    Johns, Beverley H.; Keenan, John P.

    This book offers educators guidelines for appropriately dealing with aggression in the schools and ways to increase school safety for all students. The 13 chapters address the following topics: (1) evaluating a school for safety, which includes a checklist to use in reviewing policies, facilities, students, and staff; (2) principles of peaceful…

  20. A total system approach to sustainable pest management

    PubMed Central

    Lewis, W. J.; van Lenteren, J. C.; Phatak, Sharad C.; Tumlinson, J. H.

    1997-01-01

    A fundamental shift to a total system approach for crop protection is urgently needed to resolve escalating economic and environmental consequences of combating agricultural pests. Pest management strategies have long been dominated by quests for “silver bullet” products to control pest outbreaks. However, managing undesired variables in ecosystems is similar to that for other systems, including the human body and social orders. Experience in these fields substantiates the fact that therapeutic interventions into any system are effective only for short term relief because these externalities are soon “neutralized” by countermoves within the system. Long term resolutions can be achieved only by restructuring and managing these systems in ways that maximize the array of “built-in” preventive strengths, with therapeutic tactics serving strictly as backups to these natural regulators. To date, we have failed to incorporate this basic principle into the mainstream of pest management science and continue to regress into a foot race with nature. In this report, we establish why a total system approach is essential as the guiding premise of pest management and provide arguments as to how earlier attempts for change and current mainstream initiatives generally fail to follow this principle. We then draw on emerging knowledge about multitrophic level interactions and other specific findings about management of ecosystems to propose a pivotal redirection of pest management strategies that would honor this principle and, thus, be sustainable. Finally, we discuss the potential immense benefits of such a central shift in pest management philosophy. PMID:9356432

  1. CHEMICAL RIGIDIZATION OF EXPANDABLE STRUCTURES.

    DTIC Science & Technology

    The objective of this program was to develop a chemical rigidization process that could be activated by an on-command mechanism and be capable of...and rigidized in the high vacuum facilities atWright-Patterson AFB, Ohio and were delivered to the Air Force. A fail-safe chemical rigidization system...have been varied from fifteen minutes to two hours. The chemical system, a vinyl-type monomer, has exhibited a sustained shelf-life, under ambient

  2. Efficiently, Effectively Detecting Mobile App Bugs with AppDoctor

    DTIC Science & Technology

    2014-04-01

    1 ∼ 5 ACV Comic Viewer 2 1 ∼ 5 Yes OpenSudoku 1 1 ∼ 5 Yes OI Notepad 1 0.1 ∼ 0.5 Yes OI Safe 1 0.1 ∼ 0.5 Yes Table 1: Each app’s bug count. First row... Comic Viewer Incorrect assumption of the presence of Google Services caused a crash Reported 6 ACV Comic Viewer Failed to check for the failure of

  3. FAIL-SAFE: Fault Aware IntelLigent Software for Exascale

    DTIC Science & Technology

    2016-06-13

    and that these programs can continue to correct solutions. To broaden the impact of this research, we also needed to be able to ameliorate errors...designing an interface between the application and an introspection framework for resilience ( IFR ) based on the inference engine SHINE; (4) using...the ROSE compiler to translate annotations into reasoning rules for the IFR ; and (5) designing a Knowledge/Experience Database, which will store

  4. The U.S. Food and Drug Administration's Evaluation of the Safety of Animal Clones: A Failure to Recognize the Normativity of Risk Assessment Projects

    ERIC Educational Resources Information Center

    Meghani, Zahra; de Melo-Martin, Inmaculada

    2009-01-01

    The U.S. Food and Drug Administration (FDA) announced recently that food products derived from some animal clones and their offspring are safe for human consumption. In response to criticism that it had failed to engage with ethical, social, and economic concerns raised by livestock cloning, the FDA argued that addressing normative issues prior to…

  5. An Approach to Forward Presence in a Resource-Constrained Environment

    DTIC Science & Technology

    2013-03-01

    working quietly to coordinate cooperation between Indonesia, Malaysia , and Singapore , who were historically distrustful of each other. Through...freedom of action. Non-state actors will likely seek to capitalize on these weakening and corrupt failing states as potential safe havens. The low...11 Figure 1. 2011 Defense Spending: United States vs . 16 Next Leading Spenders44 Department of Defense can feel like it is hard pressed for

  6. 27 CFR 53.159 - Deposit requirement for deposits made for calendar quarters beginning on or after July 1, 1995.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... required under this part, the appropriate TTB officer may withdraw the person's right to use the safe... officer may also require a taxpayer who fails to make deposits of tax to file a monthly or semimonthly...-25, each deposit required to be made by this section shall be made not later than the 9th day of the...

  7. Fail-Safe Design for Large Capacity Lithium-Ion Battery Systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kim, G. H.; Smith, K.; Ireland, J.

    2012-07-15

    A fault leading to a thermal runaway in a lithium-ion battery is believed to grow over time from a latent defect. Significant efforts have been made to detect lithium-ion battery safety faults to proactively facilitate actions minimizing subsequent losses. Scaling up a battery greatly changes the thermal and electrical signals of a system developing a defect and its consequent behaviors during fault evolution. In a large-capacity system such as a battery for an electric vehicle, detecting a fault signal and confining the fault locally in the system are extremely challenging. This paper introduces a fail-safe design methodology for large-capacity lithium-ionmore » battery systems. Analysis using an internal short circuit response model for multi-cell packs is presented that demonstrates the viability of the proposed concept for various design parameters and operating conditions. Locating a faulty cell in a multiple-cell module and determining the status of the fault's evolution can be achieved using signals easily measured from the electric terminals of the module. A methodology is introduced for electrical isolation of a faulty cell from the healthy cells in a system to prevent further electrical energy feed into the fault. Experimental demonstration is presented supporting the model results.« less

  8. Effects of foot reflexology on fatigue, sleep and pain: a systematic review and meta-analysis.

    PubMed

    Lee, Jeongsoon; Han, Misook; Chung, Younghae; Kim, Jinsun; Choi, Jungsook

    2011-12-01

    The purpose of this study was to evaluate the effectiveness of foot reflexology on fatigue, sleep and pain. A systematic review and meta-analysis were conducted. Electronic database and manual searches were conducted on all published studies reporting the effects of foot reflexology on fatigue, sleep, and pain. Forty four studies were eligible including 15 studies associated with fatigue, 18 with sleep, and 11 with pain. The effects of foot reflexology were analyzed using Comprehensive Meta-Analysis Version 2.0. The homogeneity and the fail-safe N were calculated. Moreover, a funnel plot was used to assess publication bias. The effects on fatigue, sleep, and pain were not homogeneous and ranged from 0.63 to 5.29, 0.01 to 3.22, and 0.43 to 2.67, respectively. The weighted averages for fatigue, sleep, and pain were 1.43, 1.19, and 1.35, respectively. No publication bias was detected as evaluated by fail-safe N. Foot reflexology had a larger effect on fatigue and sleep and a smaller effect on pain. This meta-analysis indicates that foot reflexology is a useful nursing intervention to relieve fatigue and to promote sleep. Further studies are needed to evaluate the effects of foot reflexology on outcome variables other than fatigue, sleep and pain.

  9. [Use of Gastrografin(®) in the management of adhesion intestinal obstruction].

    PubMed

    Mora López, Laura; Serra-Aracil, Xavier; Llaquet Bayo, Heura; Navarro Soto, Salvador

    2013-01-01

    Adhesions are the most important cause of intestinal obstruction. Approximately 25% of surgical admissions for acute abdominal conditions are due to intestinal obstruction. Better diagnostic and treatment methods of intestinal obstruction could potentially reduce mortality rate to 5-10%. Gastrografin(®) could contribute to this achieve this. To present a protocol to treat adhesion intestinal obstruction with Gastrografin(®) that is safe, and allows shorter hospital stays and shorter time between admission and surgery. All patients with adhesion intestinal obstruction without symptoms of strangulation were treated with Gastrografin(®), intravenous fluids and nasogastric tube. Those in whom contrast reach the colon in 8, 12 or 24hours were considered to have partial obstruction, and were fed orally. If Gastrografin(®) failed in the following 24hours, a laparotomy was performed. Out of a total of 211 episodes (164 patients), 170 episodes received contrast and in 142 cases Gastrografin(®) reached the colon (104 episodes at 8h, 11 at 12h, and 27 at 24h). A laparotomy was required in 28 patients because of failed treatment, and in another 5 for other causes. A management protocol for adhesion intestinal obstruction with Gastrografin(®) is safe, reduces morbidity and mortality, and leads to a shorter hospital stay. Copyright © 2012 AEC. Published by Elsevier Espana. All rights reserved.

  10. Needle Revision With 5-fluorouracil for the Treatment of Ahmed Glaucoma Valve Filtering Blebs: 5-Fluoruracil Needling Revision can be a Useful and Safe Tool in the Management of Failing Ahmed Glaucoma Valve Filtering Blebs.

    PubMed

    Quaranta, Luciano; Floriani, Irene; Hollander, Lital; Poli, Davide; Katsanos, Andreas; Konstas, Anastasios G P

    2016-04-01

    To determine the outcome of needling with adjunctive 5-fluorouracil (5-FU) in patients with a failing Ahmed glaucoma valve (AGV) implant, and to identify predictors of long-term intraocular pressure (IOP) control. A prospective observational study was performed on consecutive patients with medically uncontrolled primary open-angle glaucoma (POAG) with AGV encapsulation or fibrosis and inadequate IOP control. Bleb needling with 5-FU injection (0.1 mL of 50 mg/mL) was performed at the slit-lamp. Patients were examined 1 week following the needling, and then at months 1, 3, and 6. Subsequent follow-up visits were scheduled at 6-month intervals for at least 2 years. Needling with 5-FU was repeated no more than twice during the first 3 months of the follow-up. Procedure outcome was determined on the basis of the recorded IOP levels. Thirty-six patients with an encapsulated or fibrotic AGV underwent 67procedures (mean 1.86 ± 0.83). Complete success, defined as IOP ≤ 18 mm Hg without medications, was obtained in 25% at 24 months of observation. The cumulative proportion of cases achieving either qualified (ie, IOP ≤ 18 mm Hg with medications) or complete success at 24 months of observation was 72.2%. In a univariate Cox proportional hazards model, age was the only variable that independently influenced the risk of failing 5-FU needling revision. Fourteen eyes (38.8%) had a documented complication. Needling over the plate of an AGV supplemented with 5-FU is an effective and safe choice in a significant proportion of POAG patients with elevated IOP due to encapsulation or fibrosis.

  11. Recombinant Newcastle disease viral vector expressing hemagglutinin or fusion of canine distemper virus is safe and immunogenic in minks.

    PubMed

    Ge, Jinying; Wang, Xijun; Tian, Meijie; Gao, Yuwei; Wen, Zhiyuan; Yu, Guimei; Zhou, Weiwei; Zu, Shulong; Bu, Zhigao

    2015-05-15

    Canine Distemper Virus (CDV) infects many carnivores and cause several high-mortality disease outbreaks. The current CDV live vaccine cannot be safely used in some exotic species, such as mink and ferret. Here, we generated recombinant lentogenic Newcastle disease virus (NDV) LaSota expressing either envelope glycoproyein, heamagglutinine (H) or fusion protein (F), named as rLa-CDVH and rLa-CDVF, respectively. The feasibility of these recombinant NDVs to serve as live virus-vectored CD vaccine was evaluated in minks. rLa-CDVH induced significant neutralization antibodies (NA) to CDV and provided solid protection against virulent CDV challenge. On the contrast, rLa-CDVF induced much lower NA to CDV and fail to protected mink from virulent CDV challenge. Results suggest that recombinant NDV expressing CDV H is safe and efficient candidate vaccine against CDV in mink, and maybe other host species. Copyright © 2015 Elsevier Ltd. All rights reserved.

  12. Solar Photovoltaic DC Systems: Basics and Safety: Preprint

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McNutt, Peter F; Sekulic, William R; Dreifuerst, Gary

    Solar Photovoltaic (PV) systems are common and growing with 42.4 GW installed capacity in U.S. (almost 15 GW added in 2016). This paper will help electrical workers, and emergency responders understand the basic operating principles and hazards of PV DC arrays. We briefly discuss the following aspects of solar photovoltaic (PV) DC systems: the effects of solar radiation and temperature on output power; PV module testing standards; common system configurations; a simple PV array sizing example; NEC guidelines and other safety features; DC array commissioning, periodic maintenance and testing; arc-flash hazard potential; how electrical workers and emergency responders can andmore » do work safely around PV arrays; do moonlight and artificial lighting pose a real danger; typical safe operating procedures; and other potential DC-system hazards to be aware of. We also present some statistics on PV DC array electrical incidents and injuries. Safe PV array operation is possible with a good understanding of PV DC arrays basics and having good safe operating procedures in place.« less

  13. MRI for peripheral artery disease: Introductory physics for vascular physicians.

    PubMed

    Roy, Trisha L; Forbes, Thomas L; Dueck, Andrew D; Wright, Graham A

    2018-04-01

    Magnetic resonance imaging (MRI) has advanced significantly in the past decade and provides a safe and non-invasive method of evaluating peripheral artery disease (PAD), with and without using exogenous contrast agents. MRI offers a promising alternative for imaging patients but the complexity of MRI can make it less accessible for physicians to understand or use. This article provides a brief introduction to the technical principles of MRI for physicians who manage PAD patients. We discuss the basic principles of how MRI works and tailor the discussion to how MRI can evaluate anatomic characteristics of peripheral arterial lesions.

  14. The time-efficiency principle: time as the key diagnostic strategy in primary care.

    PubMed

    Irving, Greg; Holden, John

    2013-08-01

    The test and retest opportunity afforded by reviewing a patient over time substantially increases the total gain in certainty when making a diagnosis in low-prevalence settings (the time-efficiency principle). This approach safely and efficiently reduces the number of patients who need to be formally tested in order to make a correct diagnosis for a person. Time, in terms of observed disease trajectory, provides a vital mechanism for achieving this task. It remains the best strategy for delivering near-optimal diagnoses in low-prevalence settings and should be used to its full advantage.

  15. The Principle and the Application of Self-cleaning Anti-pollution Coating in Power System

    NASA Astrophysics Data System (ADS)

    Zhao, Y. J.; Zhang, Z. B.; Liu, Y.; Wang, J. H.; Teng, J. L.; Wu, L. S.; Zhang, Y. L.

    2017-11-01

    The common problem existed in power system is analyzed in this paper. The main reason for the affection of the safe and stable operation to power equipment is flash-over caused by dirt and discharge. Using the self-cleaning anti-pollution coating in the power equipment surface is the key to solve the problem. In the work, the research progress and design principle about the self-cleaning anti-pollution coating was summarized. Furthermore, the preparation technology was also studied. Finally, the application prospect of hard self-cleaning anti-pollution coating in power system was forecast.

  16. Setting and validating the pass/fail score for the NBDHE.

    PubMed

    Tsai, Tsung-Hsun; Dixon, Barbara Leatherman

    2013-04-01

    This report describes the overall process used for setting the pass/fail score for the National Board Dental Hygiene Examination (NBDHE). The Objective Standard Setting (OSS) method was used for setting the pass/fail score for the NBDHE. The OSS method requires a panel of experts to determine the criterion items and proportion of these items that minimally competent candidates would answer correctly, the percentage of mastery and the confidence level of the error band. A panel of 11 experts was selected by the Joint Commission on National Dental Examinations (Joint Commission). Panel members represented geographic distribution across the U.S. and had the following characteristics: full-time dental hygiene practitioners with experience in areas of preventive, periodontal, geriatric and special needs care, and full-time dental hygiene educators with experience in areas of scientific basis for dental hygiene practice, provision of clinical dental hygiene services and community health/research principles. Utilizing the expert panel's judgments, the pass/fail score was set and then the score scale was established using the Rasch measurement model. Statistical and psychometric analysis shows the actual failure rate and the OSS failure rate are reasonably consistent (2.4% vs. 2.8%). The analysis also showed the lowest error of measurement, an index of the precision at the pass/fail score point and that the highest reliability (0.97) are achieved at the pass/fail score point. The pass/fail score is a valid guide for making decisions about candidates for dental hygiene licensure. This new standard was reviewed and approved by the Joint Commission and was implemented beginning in 2011.

  17. The perceived compatibility of safety and production expectations in hazardous occupations.

    PubMed

    McLain, David L; Jarrell, Kimberly A

    2007-01-01

    Safety hazards are unavoidable in many work environments. Employees must be both productive and safe, however, conflicting safety and production demands can negatively affect safety, production, or both. The employee's perception of the compatibility of management's safety and production expectations is a possible predictor of such consequences. This paper defines "safety-production compatibility" and describes how measures of safety-production compatibility, as well as safety pressure and production pressure, were developed. We used LISREL structural equation modeling to test the influences of safety-production compatibility, safety pressure, and production pressure on safe work behavior and interference with performing other work tasks. The 239 study participants were workers employed in diverse but hazardous occupations. Pressure to work safely was positively associated with safe work behavior. The perceived compatibility of safety and production demands positively influenced safe work behavior and reduced the interference of safety hazards performing other tasks. Safety-production compatibility was also found to mediate the relationship between trust in management and safe work behavior. The results of this field study suggest increased compatibility, and thus less conflict, between safety and production demands influences safe work behavior and the interference of safety hazards with performing other work tasks. More broadly, the worker's reaction to multiple work demands is a safety and performance influence. Safety management efforts that focus only on the hazards fail to eliminate many accidents because accidents arise from many factors including technology, safety climate, social influences, production, and safety demands. This study suggests that workers differ in their perception of the compatibility of safety and production demands. These differences will show up in safe work behavior, influencing the effectiveness of safety management efforts and the trust workers have in management's concern for safety.

  18. Implementation and implication of total quality management on client- contractor relationship in residential projects

    NASA Astrophysics Data System (ADS)

    Murali, Swetha; Ponmalar, V.

    2017-07-01

    To make innovation and continuous improvement as a norm, some traditional practices must become unlearnt. Change for growth and competitiveness are required for sustainability for any profitable business such as the construction industry. The leading companies are willing to implement Total Quality Management (TQM) principles, to realise potential advantages and improve growth and efficiency. Ironically, researches recollected quality as the most significant provider for competitive advantage in industrial leadership. The two objectives of this paper are 1) Identify TQM effectiveness in residential projects and 2) Identify the client satisfaction/dissatisfaction areas using Analytical Hierarchy Process (AHP) and suggest effective mitigate measures. Using statistical survey techniques like set of questionnaire survey, it is observed that total quality management was applied in some leading successful organization to an extent. The main attributes for quality achievement can be defined as teamwork and better communication with single agreed goal between client and contractor. Onsite safety is a paramount attribute in the identifying quality within the residential projects. It was noticed that the process based quality methods such as onsite safe working condition; safe management system and modern engineering process safety controls etc. as interlinked functions. Training and effective communication with all stakeholders on quality management principles is essential for effective quality work. Late Only through effective TQM principles companies can avoid some contract litigations with an increased client satisfaction Index.

  19. Ensuring Food Integrity by Metrology and FAIR Data Principles

    PubMed Central

    Rychlik, Michael; Zappa, Giovanna; Añorga, Larraitz; Belc, Nastasia; Castanheira, Isabel; Donard, Olivier F. X.; Kouřimská, Lenka; Ogrinc, Nives; Ocké, Marga C.; Presser, Karl; Zoani, Claudia

    2018-01-01

    Food integrity is a general term for sound, nutritive, healthy, tasty, safe, authentic, traceable, as well as ethically, safely, environment-friendly, and sustainably produced foods. In order to verify these properties, analytical methods with a higher degree of accuracy, sensitivity, standardization and harmonization and a harmonized system for their application in analytical laboratories are required. In this view, metrology offers the opportunity to achieve these goals. In this perspective article the current global challenges in food analysis and the principles of metrology to fill these gaps are presented. Therefore, the pan-European project METROFOOD-RI within the framework of the European Strategy Forum on Research Infrastructures (ESFRI) was developed to establish a strategy to allow reliable and comparable analytical measurements in foods along the whole process line starting from primary producers until consumers and to make all data findable, accessible, interoperable, and re-usable according to the FAIR data principles. The initiative currently consists of 48 partners from 18 European Countries and concluded its “Early Phase” as research infrastructure by organizing its future structure and presenting a proof of concept by preparing, distributing and comprehensively analyzing three candidate Reference Materials (rice grain, rice flour, and oyster tissue) and establishing a system how to compile, process, and store the generated data and how to exchange, compare them and make them accessible in data bases. PMID:29872651

  20. Ensuring Food Integrity by Metrology and FAIR Data Principles

    NASA Astrophysics Data System (ADS)

    Rychlik, Michael; Zappa, Giovanna; Añorga, Larraitz; Belc, Nastasia; Castanheira, Isabel; Donard, Olivier F. X.; Kouřimská, Lenka; Ogrinc, Nives; Ocké, Marga C.; Presser, Karl; Zoani, Claudia

    2018-05-01

    Food integrity is a general term for sound, nutritive, healthy, tasty, safe, authentic, traceable, as well as ethically, safely, environment-friendly and sustainably produced foods. In order to verify these properties, analytical methods with a higher degree of accuracy, sensitivity, standardization and harmonization and a harmonized system for their application in analytical laboratories are required. In this view, metrology offers the opportunity to achieve these goals. In this perspective article the current global challenges in food analysis and the principles of metrology to fill these gaps are presented. Therefore, the pan-European project METROFOOD-RI within the framework of the European Strategy Forum on Research Infrastructures (ESFRI) was developed to establish a strategy to allow reliable and comparable analytical measurements in foods along the whole process line starting from primary producers until consumers and to make all data findable, accessible, interoperable, and re-usable according to the FAIR data principles. The initiative currently consists of 48 partners from 18 European Countries and concluded its “Early Phase” as research infrastructure by organizing its future structure and presenting a proof of concept by preparing, distributing and comprehensively analyzing three candidate Reference Materials (rice grain, rice flour and oyster tissue) and establishing a system how to compile, process and store the generated data and how to exchange, compare them and make them accessible in data bases.

  1. Ensuring Food Integrity by Metrology and FAIR Data Principles.

    PubMed

    Rychlik, Michael; Zappa, Giovanna; Añorga, Larraitz; Belc, Nastasia; Castanheira, Isabel; Donard, Olivier F X; Kouřimská, Lenka; Ogrinc, Nives; Ocké, Marga C; Presser, Karl; Zoani, Claudia

    2018-01-01

    Food integrity is a general term for sound, nutritive, healthy, tasty, safe, authentic, traceable, as well as ethically, safely, environment-friendly, and sustainably produced foods. In order to verify these properties, analytical methods with a higher degree of accuracy, sensitivity, standardization and harmonization and a harmonized system for their application in analytical laboratories are required. In this view, metrology offers the opportunity to achieve these goals. In this perspective article the current global challenges in food analysis and the principles of metrology to fill these gaps are presented. Therefore, the pan-European project METROFOOD-RI within the framework of the European Strategy Forum on Research Infrastructures (ESFRI) was developed to establish a strategy to allow reliable and comparable analytical measurements in foods along the whole process line starting from primary producers until consumers and to make all data findable, accessible, interoperable, and re-usable according to the FAIR data principles. The initiative currently consists of 48 partners from 18 European Countries and concluded its "Early Phase" as research infrastructure by organizing its future structure and presenting a proof of concept by preparing, distributing and comprehensively analyzing three candidate Reference Materials (rice grain, rice flour, and oyster tissue) and establishing a system how to compile, process, and store the generated data and how to exchange, compare them and make them accessible in data bases.

  2. Individual differences in political ideology are effects of adaptive error management.

    PubMed

    Petersen, Michael Bang; Aarøe, Lene

    2014-06-01

    We apply error management theory to the analysis of individual differences in the negativity bias and political ideology. Using principles from evolutionary psychology, we propose a coherent theoretical framework for understanding (1) why individuals differ in their political ideology and (2) the conditions under which these individual differences influence and fail to influence the political choices people make.

  3. Lifelong Literacy: Some Trends and Issues in Conceptualising and Operationalising Literacy from a Lifelong Learning Perspective

    ERIC Educational Resources Information Center

    Hanemann, Ulrike

    2015-01-01

    In a fast-changing and highly inequitable world, lifelong learning is becoming increasingly important, not only as a key organising principle for all forms of education and learning but also as an absolute necessity for everyone. It is particularly important for disadvantaged individuals and groups who have been excluded from or failed to acquire…

  4. Professor Usain Bolt Welcomes You to the Schoolyard: Physics for Champions

    ERIC Educational Resources Information Center

    Vourlias, Kostas; Seroglou, Fanny

    2016-01-01

    Could Usain Bolt achieve what teachers often fail to do? Could this famous Olympic winner challenge and motivate students to study mechanics and introduce them to the principles of physics in a fun way, outside of the classroom? In order to answer these questions, we "invited" for one semester the world record holder to visit our Greek…

  5. Rediscovering the Kernels of Truth in the Urban Legends of the Freshman Composition Classroom

    ERIC Educational Resources Information Center

    Lovoy, Thomas

    2004-01-01

    English teachers, as well as teachers within other disciplines, often boil down abstract principles to easily explainable bullet points. Students often pick up and retain these points but fail to grasp the broader contexts that make them relevant. It is therefore sometimes helpful to revisit some of the more common of these "rules of thumb" to…

  6. Simple-Minded Accountability Measures Create Failing Schools in Disadvantaged Contexts: A Case Study of a Swedish Junior High School

    ERIC Educational Resources Information Center

    Allodi, Mara Westling

    2013-01-01

    The principles of new public management -- market mechanisms, accountability and standards -- have been applied in the education system. These methods are supposed to increase efficiency, but there is also a risk of negative consequences from the services provided if the measures of performance target a reduced range of goals, ignore relevant…

  7. Beyond Recycling: Guiding Preservice Teachers to Understand and Incorporate the Deeper Principles of Sustainability

    ERIC Educational Resources Information Center

    Bauermeister, Maxine L.; Diefenbacher, Lori H.

    2015-01-01

    Sustainability is a term with an evolving definition that applies to more than the physical environment. It speaks to the interconnectivity of every action we take (or fail to take) and to human beings' relationships with one another and their environment. A sustainable future is one in which global citizens engage in critical thinking,…

  8. Driving with diabetes: the automatism defence.

    PubMed

    Griffith, Richard; Tengnah, Cassam

    2011-02-01

    The tragic case of a district nurse killed when a car driven by a man in a hypoglycaemic state struck her while she took her regular evening walk highlights the dangers that can occur when a person with diabetes drives without regard to their condition. The man was later jailed for four and a half years for causing death by dangerous driving having been found criminally responsible for his actions because he failed to control his blood sugar levels during the journey. In this article the authors set out the likely consequences for people with diabetes who fail in their duty to ensure that they are able to drive safely and are unlikely to be affected by the adverse effects of their illness or the medication taken to control it.

  9. Human error identification for laparoscopic surgery: Development of a motion economy perspective.

    PubMed

    Al-Hakim, Latif; Sevdalis, Nick; Maiping, Tanaphon; Watanachote, Damrongpan; Sengupta, Shomik; Dissaranan, Charuspong

    2015-09-01

    This study postulates that traditional human error identification techniques fail to consider motion economy principles and, accordingly, their applicability in operating theatres may be limited. This study addresses this gap in the literature with a dual aim. First, it identifies the principles of motion economy that suit the operative environment and second, it develops a new error mode taxonomy for human error identification techniques which recognises motion economy deficiencies affecting the performance of surgeons and predisposing them to errors. A total of 30 principles of motion economy were developed and categorised into five areas. A hierarchical task analysis was used to break down main tasks of a urological laparoscopic surgery (hand-assisted laparoscopic nephrectomy) to their elements and the new taxonomy was used to identify errors and their root causes resulting from violation of motion economy principles. The approach was prospectively tested in 12 observed laparoscopic surgeries performed by 5 experienced surgeons. A total of 86 errors were identified and linked to the motion economy deficiencies. Results indicate the developed methodology is promising. Our methodology allows error prevention in surgery and the developed set of motion economy principles could be useful for training surgeons on motion economy principles. Copyright © 2015 Elsevier Ltd and The Ergonomics Society. All rights reserved.

  10. Magnetic-field enhancement beyond the skin-depth limit

    NASA Astrophysics Data System (ADS)

    Shin, Jonghwa; Park, Namkyoo; Fan, Shanhui; Lee, Yong-Hee

    2010-02-01

    Electric field enhancement has been actively studied recently and many metallic structures that are capable of locally enhancing electric field have been reported. The Babinet's principle can be utilized, especially in the form of Booker's extension, to transform the known electric field enhancing structures into magnetic field enhancing structures. The authors explain this transformation process and discuss the regime in which this principle breaks down. Unless the metals used can be well approximated with a PEC model, the principle's predictions fails to hold true. Authors confirm this aspect using numerical simulations based on realistic material parameters for actual metals. There is large discrepancy especially when the structural dimensions are comparable or less than the skin-depth at the wavelength of interest. An alternative way to achieve magnetic field enhancement is presented and the design of a connected bow-tie structure is proposed as an example. FDTD simulation results confirm the operation of the proposed structure.

  11. Unit: Science and Safety, Inspection Set, National Trial Print.

    ERIC Educational Resources Information Center

    Australian Science Education Project, Toorak, Victoria.

    This unit, a trial version prepared by the Australian Science Education Project, is intended to create in students an awareness of the potential hazards of a science room, to help build confidence by teaching safe techniques of apparatus manipulation, and to demonstrate the utility of planning work thoroughly. The safety principles are extended to…

  12. 24 CFR 1000.2 - What are the guiding principles in the implementation of NAHASDA?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Indian tribes and a unique Federal responsibility to Indian people. (3) The Constitution of the United... implementation of NAHASDA: (1) The Federal government has a responsibility to promote the general welfare of the Nation: (i) By using Federal resources to aid families and individuals seeking affordable homes in safe...

  13. 49 CFR 236.1015 - PTC Safety Plan content requirements and PTC System Certification.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... established and can maintain a quality control system for PTC system design and manufacturing acceptable to... an explanation of the design principles and assumptions; (3) A risk assessment of the as-built PTC... the specific procedures and test equipment necessary to ensure the safe and proper installation...

  14. Principles of Safety in Physical Education and Sport.

    ERIC Educational Resources Information Center

    Dougherty, Neil J., IV, Ed.

    This book was designed to provide the professional with a straightforward and complete resource for those factors that must be considered in the provision of safe units of instruction in the commonly taught sports and activities. Twenty-one chapters provide essential information, checklists, and outlines, as well as ways to ensure student safety.…

  15. Learning Outdoors: Leader Guide, Grade 3. 4-H Discovery.

    ERIC Educational Resources Information Center

    Abell, John R.; Newman, Jerry A.

    The United States has a rich natural resource heritage. It is important to educate students in the principles of conservation so that these natural resources may endure for generations. This guide is designed to help leaders to learn to organize groups of children and conduct successful meetings; provide fun, safe, outdoor learning experiences for…

  16. 24 CFR 1000.2 - What are the guiding principles in the implementation of NAHASDA?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Nation: (i) By using Federal resources to aid families and individuals seeking affordable homes in safe... marketplace and allow families to prosper without government involvement in their day-to-day activities. (2... an essential element in the special role of the United States in helping Indian tribes and their...

  17. 24 CFR 1000.2 - What are the guiding principles in the implementation of NAHASDA?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Nation: (i) By using Federal resources to aid families and individuals seeking affordable homes in safe... marketplace and allow families to prosper without government involvement in their day-to-day activities. (2... an essential element in the special role of the United States in helping Indian tribes and their...

  18. 24 CFR 1000.2 - What are the guiding principles in the implementation of NAHASDA?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Nation: (i) By using Federal resources to aid families and individuals seeking affordable homes in safe... marketplace and allow families to prosper without government involvement in their day-to-day activities. (2... an essential element in the special role of the United States in helping Indian tribes and their...

  19. Recreation and Leisure. DB-LINK Fact Sheet. Revised.

    ERIC Educational Resources Information Center

    Lieberman, Lauren

    This brief guide presents principles and suggestions to help individuals who are deaf-blind enjoy and benefit from participation in recreational activities. Some considerations discussed are to: (1) start with the individual and determine what he or she is interested in, focusing on the selection of safe, age-appropriate activities; (2) research…

  20. 76 FR 81508 - Communications and Activities Related to Off-Label Uses of Marketed Products and Use of Products...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-28

    ... derived from clinical investigations and presented as part of a marketing application. The marketing... product is safe and effective for its intended uses, as reflected in the marketing application, it... general principles underlying the IND submission and the general requirements for an IND's content and...

  1. 26 CFR 1.475(a)-4 - Valuation safe harbor.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... may or may not be subject to mark-to-market accounting under section 475. (c) Eligible taxpayer. An... standard that arrives at fair value in accordance with U.S. Generally Accepted Accounting Principles (U.S.... (iii) Accounting for costs and risks. Valuations may account for appropriate costs and risks, but no...

  2. A Guide to School Vulnerability Assessments: Key Principles for Safe Schools

    ERIC Educational Resources Information Center

    Office of Safe and Drug-Free Schools, US Department of Education, 2008

    2008-01-01

    Crises affect schools across the country every day. While natural hazards such as tornadoes, floods, hurricanes, and earthquakes may be thought of more commonly as emergencies, schools are also at risk from other hazards such as school violence, infectious disease, and terrorist threats. Through the vulnerability assessment process, schools can…

  3. Ecosystem management and our national forests -- is there a role for forest herbicides?

    Treesearch

    Charles K. McMahon; J.H. Miller; D.F. Thomas

    1994-01-01

    Abstract.Environmentally safe, selective herbicide treatments can be adapted to manage habitats and direct succession toward desired future conditions within the principles of Ecosystem Management (EM). Six roles for herbicide treatments in EM are suggested: create and maintain desired habitats; create mixed and unevenaged stands; restore damaged...

  4. The Corruption Bogey in South Africa: Is Public Education Safe?

    ERIC Educational Resources Information Center

    Serfontein, Erika; de Waal, Elda

    2015-01-01

    Corruption is a constant global phenomenon, which is becoming more complex and intense as competition for resources increases. It is even more so amongst those living in developing countries, particularly emerging economies such as South Africa. Acts of corruption directly contest the basic principles of South Africa's Constitution, which aims at…

  5. QUESTION--WHAT MAKES A SCHOOL SITE SAFE. ANSWER--DEFINITE PLANNING.

    ERIC Educational Resources Information Center

    GEORGE, N.L.; GILLILAND, LONNIE, SR.

    TWO STAFF MEMBERS FROM A SYSTEM OF PUBLIC SCHOOLS, THE ASSISTANT SUPERINTENDENT, AND THE DIRECTOR OF SAFETY EDUCATION DISCUSSED THE PROBLEMS OF TRAFFIC SAFETY ON AND AROUND THE SCHOOL SITE. FACTORS WHICH WERE CONSIDERED INCLUDE--(1) SCHOOL SITE AND BUILDING LOCATION, (2) SAFETY REQUIREMENTS, PRACTICES AND PRINCIPLES, (3) SIDEWALK DESIGN AND…

  6. Implementing Restorative Justice Practice in Schools: What Pedagogy Reveals

    ERIC Educational Resources Information Center

    Vaandering, Dorothy

    2014-01-01

    In the ongoing pursuit for creating safe, nurturing and relational school cultures, educators continue to turn to restorative justice (rj) principles and practice. Predominantly, schools begin to engage with rj in an effort to address harm done, causing its discourse to be situated in literature tied to classroom management and behaviour. However,…

  7. The Adverse Effects of Le Châtelier's Principle on Teacher Understanding of Chemical Equilibrium

    NASA Astrophysics Data System (ADS)

    Cheung, Derek

    2009-04-01

    Although the scientific inadequacy of Le Châtelier's principle has long been documented in the literature, the principle is still treated as a central concept of chemical equilibrium by textbook writers and teachers in many countries. In the past, researchers' interest has focused on student misconceptions about chemical equilibrium and has neglected teacher misconceptions. This study aimed to determine how Le Châtelier's principle adversely affects teachers' ability to solve chemical equilibrium problems. This area of research is critically important because teachers cannot help their students understand what they themselves do not understand. In this study, a misconception test was developed and administered to a sample of 33 secondary chemistry teachers in Hong Kong. The test consisted of three open-ended chemical equilibrium questions. Analysis of teacher responses revealed that most of the 33 teachers failed the test as they relied on Le Châtelier's principle rather than the equilibrium law to tackle the three chemical equilibrium problems. Teachers' misconceptions about chemical equilibrium were categorized. Implications of these findings for chemistry teacher education and selection of curriculum content for school chemistry are discussed.

  8. Foundational principles of classical Ayurveda research

    PubMed Central

    Raha, Somik

    2013-01-01

    Double-blind randomized controlled trials (RCTs) are viewed as the golden standard of drug research in Western medicine. However, RCTs are far from “golden” in many respects. They are impractical for many therapies, such as for surgeries and complex lifestyle changes. They encourage a one-size-fits-all approach to medical treatment that fails to address the huge diversity among individual patients in terms of their physical and emotional symptoms, social and cultural upbringing, and other factors. Perhaps, more importantly, they do not help doctors make the best medical decisions required to produce optimal patient outcomes. To guide a search for an alternate model of medical research, three principles based on Ayurveda, an ancient and powerful system of health care that has stood the test of time, are presented. These principles, arrived at after mining Ayurvedic epistemology, are: Inductive learning, whole systems thinking, and individually optimized therapy. In honor of the ancient sages or “Rishis,” whose voice is used to deliver Ayurvedic knowledge in the ancient texts of Ayurveda, these are referred to as the “Rishi principles.” Common research methodologies are examined for embodiment of these principles. PMID:24459385

  9. Reconciling community-based Indigenous research and academic practices: Knowing principles is not always enough.

    PubMed

    Morton Ninomiya, Melody E; Pollock, Nathaniel J

    2017-01-01

    Historically, Indigenous health research in Canada has failed to engage Indigenous peoples and communities as primary stakeholders of research evidence. Increasingly, research ethics and methodologies are being positioned as tools for Indigenous self-determination. In response, mainstream institutions have developed new ethical principles for research involving Indigenous people. While these transformations are necessary steps towards re-orienting research practices, they are not prescriptive. In this paper, we make visible three dilemmas from a case study in which Indigenous health research frameworks provided limited guidance or were unclear about how to balance community priorities with Indigenous research principles. We also discuss the strategies used to resolve each of these dilemmas. We draw examples from a project that examined the lived experiences of children and youth living with FASD and their caregivers. This project was conducted in collaboration with Sheshatshiu Innu First Nation, an Indigenous community in Labrador, Canada. In doing so, we argue that knowing the key guiding principles in Indigenous health research is not always enough, and that the 'real-world' context of practices and relationships can lead to conflicts that are not easily resolved with adherence to these principles. Copyright © 2016 Elsevier Ltd. All rights reserved.

  10. Flightworthy active control landing gear for a supersonic aircraft

    NASA Technical Reports Server (NTRS)

    Ross, I.

    1980-01-01

    A flightworthy active control landing gear system for a supersonic aircraft was designed to minimize aircraft loads during takeoff, impact, rollout, and taxi. The design consists of hydromechanical modifications to the existing gear and the development of a fail-safe electronic controller. analytical RESULTS INDICATE that for an aircraft sink rate of 0.914 m/sec (3 ft/sec) the system achieves a peak load reduction of 36% during landing impact.

  11. Use of ustekinumab for severe refractory atopic dermatitis in a young teenager.

    PubMed

    Wlodek, C; Hewitt, H; Kennedy, C T

    2016-08-01

    When conventional systemic immunosuppressive treatments fail in the setting of severe eczema, unlike in psoriasis, there are limited treatment options and only anecdotal evidence to help guide clinicians. There is a growing body of evidence for the use of certain biologic agents for moderate to severe eczema. We report the youngest case to date successfully and safely treated with ustekinumab for severe refractory atopic dermatitis. © 2016 British Association of Dermatologists.

  12. Application of Micro-ramp Flow Control Devices to an Oblique Shock Interaction

    NASA Technical Reports Server (NTRS)

    Hirt, Stefanie; Anderson, Bernhard

    2007-01-01

    Tests are planned in the 15cm x 15cm supersonic wind tunnel at NASA Glenn to demonstrate the applicability of micro-ramp flow control to the management of shock wave boundary layer interactions. These tests will be used as a database for computational fluid dynamics (CFD) validation and Design of Experiments (DoE) design information. Micro-ramps show potential for mechanically simple and fail-safe boundary layer control.

  13. Evidence-based practice guideline: wheelchair biking for the treatment of depression.

    PubMed

    Fitzsimmons, Suzanne; Schoenfelder, Deborah Perry

    2011-07-01

    Depression is a problem that will continue to burden older adults and challenge health care providers. Failing to recognize and effectively treat depression in institutionalized older adults is sanctioning these members of society to live their final years in despair and emotional suffering. The wheelchair biking program described in this evidence-based practice guideline provides a refreshing, safe, innovative tool to address depression and improve quality of life in older adults.

  14. High Performing Schools in High Risk Environments: A Study on Leadership, School Safety, and Student Achievement at Two Urban Middle Schools in Los Angeles County

    ERIC Educational Resources Information Center

    Frias, Gus

    2010-01-01

    In the United States of America, all students and staff have a constitutional right to attend schools that are safe, secure, and successful. Despite this right, at many public schools, education leaders have failed to ensure the safety and high academic achievement of all students. The purpose of this research study is to expand knowledge about…

  15. Software Requirements for the A-7E Aircraft.

    DTIC Science & Technology

    1992-08-31

    DIWI(a) 14 ASCU SSU-20 (1,2) READ 8 DIWI(a) 15 BITE FAIL SAFE (2) READ 2 DIW3(a) 0 TACAN PARITY VALID (3) READ 2 DIW3(a) 10-14 AGE TEST EQUIPMENT (2...69 2.1.5: Arm am ent Station Control Unit ( ASCU ...times. 69 I Chapter 2 ALSPAUGH, FAULK. BRITTON, PARKER. PARNAS, AND SHORE 3 2.1.5. Armament Station Control Unit ( ASCU ) The Armament Station Control

  16. Human Cognitive Limitations. Broad, Consistent, Clinical Application of Physiological Principles Will Require Decision Support.

    PubMed

    Morris, Alan H

    2018-02-01

    Our education system seems to fail to enable clinicians to broadly understand core physiological principles. The emphasis on reductionist science, including "omics" branches of research, has likely contributed to this decrease in understanding. Consequently, clinicians cannot be expected to consistently make clinical decisions linked to best physiological evidence. This is a large-scale problem with multiple determinants, within an even larger clinical decision problem: the failure of clinicians to consistently link their decisions to best evidence. Clinicians, like all human decision-makers, suffer from significant cognitive limitations. Detailed context-sensitive computer protocols can generate personalized medicine instructions that are well matched to individual patient needs over time and can partially resolve this problem.

  17. Incompetent Patients, Substitute Decision Making, and Quality of Life: Some Ethical Considerations

    PubMed Central

    Kluge, Eike-Henner W.

    2008-01-01

    One of the most difficult situations facing physicians involves decision making by substitute decision makers for patients who have never been competent. This paper begins with a brief examination of the ethics of substitute decision making for previously competent patients. It then applies the results to substitute decision making for patients who have never been competent, and critically analyzes 5 models of substitute decision making for such patients, showing why each either contravenes basic ethical principles or fails to guarantee the use of ethically appropriate values. It concludes by sketching a modified objective reasonable person standard for substitute decision making that avoids valuational difficulties and allows for a protocol that satisfies ethical principles. PMID:19099031

  18. The opacity of the universe and the strong equivalence principle

    NASA Technical Reports Server (NTRS)

    Canuto, V. M.; Goldman, I.

    1983-01-01

    A possible explanation of why the advanced solutions of Maxwell's equations are not observed in nature is by way of absorption by an opaque universe. As Davies has shown, the ever expanding, general relativistic cosmological models fail to provide the needed absorption. The absorption mechanism calling for an interplay between local physics and cosmology, is usually developed adopting the strong equivalence principle, SEP, which precludes such interplay. It is shown that complete absorption of electromagnetic radiation by ionized intergalactic plasma is obtained provided a violation of the SEP, of the order of the Hubble's constant, is allowed to occur. The same degree of violation was previously found to be compatible with a large body of observational data.

  19. Development and Evaluation of a Systems Thinking Education Strategy for Baccalaureate Nursing Curriculum: A Pilot Study.

    PubMed

    Fura, Louise A; Wisser, Kathleen Z

    Nurse educators are charged to develop and evaluate curricula on systems thinking to prepare future nurses to provide safe nursing care. The goal of this pilot study was to design and evaluate a four-hour educational strategy that prepares future professional nurses to use systems thinking approaches in the delivery of safe patient care. This study exposed prelicensure baccalaureate nursing students to systems thinking principles, which included didactic and experiential activities. A descriptive design was used to determine the effect of an on-campus educational strategy. A paired samples t-test revealed statistical significance from pretest to posttest.

  20. Response Variability in Commercial MOSFET SEE Qualification

    DOE PAGES

    George, J. S.; Clymer, D. A.; Turflinger, T. L.; ...

    2016-12-01

    Single-event effects (SEE) evaluation of five different part types of next generation, commercial trench MOSFETs indicates large part-to-part variation in determining a safe operating area (SOA) for drain-source voltage (V DS) following a test campaign that exposed >50 samples per part type to heavy ions. These results suggest a determination of a SOA using small sample sizes may fail to capture the full extent of the part-to-part variability. An example method is discussed for establishing a Safe Operating Area using a one-sided statistical tolerance limit based on the number of test samples. Finally, burn-in is shown to be a criticalmore » factor in reducing part-to-part variation in part response. Implications for radiation qualification requirements are also explored.« less

  1. Less than severe worst case accidents

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sanders, G.A.

    1996-08-01

    Many systems can provide tremendous benefit if operating correctly, produce only an inconvenience if they fail to operate, but have extreme consequences if they are only partially disabled such that they operate erratically or prematurely. In order to assure safety, systems are often tested against the most severe environments and accidents that are considered possible to ensure either safe operation or safe failure. However, it is often the less severe environments which result in the ``worst case accident`` since these are the conditions in which part of the system may be exposed or rendered unpredictable prior to total system failure.more » Some examples of less severe mechanical, thermal, and electrical environments which may actually be worst case are described as cautions for others in industries with high consequence operations or products.« less

  2. Response Variability in Commercial MOSFET SEE Qualification

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    George, J. S.; Clymer, D. A.; Turflinger, T. L.

    Single-event effects (SEE) evaluation of five different part types of next generation, commercial trench MOSFETs indicates large part-to-part variation in determining a safe operating area (SOA) for drain-source voltage (V DS) following a test campaign that exposed >50 samples per part type to heavy ions. These results suggest a determination of a SOA using small sample sizes may fail to capture the full extent of the part-to-part variability. An example method is discussed for establishing a Safe Operating Area using a one-sided statistical tolerance limit based on the number of test samples. Finally, burn-in is shown to be a criticalmore » factor in reducing part-to-part variation in part response. Implications for radiation qualification requirements are also explored.« less

  3. Prototype data terminal-multiplexer/demultiplexer

    NASA Technical Reports Server (NTRS)

    Leck, D. E.; Goodwin, J. E.

    1972-01-01

    The design and operation of a quad redundant data terminal and a multiplexer/demultiplexer (MDU) is described. The most unique feature is the design of the quad redundant data terminal. This is one of the few designs where the unit is fail/op, fail/op, fail/safe. Laboratory tests confirm that the unit will operate satisfactorily with the failure of three out of four channels. Although the design utilizes state-of-the-art technology, the waveform error checks, the voting techniques, and the parity bit checks are believed to be used in unique configurations. Correct word selection routines are also novel. The MDU design, while not redundant, utilizes, the latest state-of-the-art advantages of light coupler and interested amplifiers. Much of the technology employed was an evolution of prior NASA contracts related to the Addressable Time Division Data System. A good example of the earlier technology development was the development of a low level analog multiplexer, a high level analog multiplexer, and a digital multiplexer. A list of all drawings is included for reference and all schematic, block and timing diagrams are incorporated.

  4. [Ethical principles of clinical trials in minors].

    PubMed

    Koch, H J; Raschka, C

    2002-12-05

    Clinical trials in volunteers and patients are essential to ensure rational treatment of patients. As a rule, drugs are routinely developed for adults, but children are excluded. A major reason for this restriction are ethical justifications, in particular the lack of autonomy on the part of children. The principle of fairness, however, requires that everyone should benefit from progress. Industry, science and society are therefore called upon to find ways of making available safe and adequate treatment for children as quickly as possible, by defining the required conditions for pediatric clinical trials. Important principles are minimal risk, minimal invasivity, rapid decision-making, and careful documentation of trial results. Dynamic ethical principles, such as autonomy and competence in adolescents must be considered on equal footing with existing international GCP guidelines. Aspects of child psychology indicate that the autonomy of adolescents should be respected. Where economic incentives for such trials are absent, for example, in the case of non-pharmacological problems, pediatric trials must be considered a task for society as a whole.

  5. Buzzing Bugs and Creepy Crawlies: A Lesson in Tolerance and Design

    ERIC Educational Resources Information Center

    Coy, Mary

    2005-01-01

    This author relates how she used to hate bugs but a museum visit changed her perception about them. She realized that in her panic of shooing insects away, she failed to recognize them as living models of the elements and principles of design. It made her realize that insects can provide an opportunity to teach this important lesson to her seventh…

  6. Development of Mathematical Knowledge in Young Children: Attentional Skill and the Use of Inversion

    ERIC Educational Resources Information Center

    Watchorn, Rebecca P. D.; Bisanz, Jeffrey; Fast, Lisa; LeFevre, Jo-Anne; Skwarchuk, Sheri-Lynn; Smith-Chant, Brenda L.

    2014-01-01

    The principle of "inversion," that a + b - b "must" equal a, is a fundamental property of arithmetic, but many children fail to apply it in symbolic contexts through 10 years of age. We explore three hypotheses relating to the use of inversion that stem from a model proposed by Siegler and Araya (2005). Hypothesis 1 is that…

  7. Improved Electromagnetic Brake

    NASA Technical Reports Server (NTRS)

    Martin, Toby B.

    2004-01-01

    A proposed design for an electromagnetic brake would increase the reliability while reducing the number of parts and the weight, relative to a prior commercially available electromagnetic brake. The reductions of weight and the number of parts could also lead to a reduction of cost. A description of the commercial brake is prerequisite to a description of the proposed electromagnetic brake. The commercial brake (see upper part of figure) includes (1) a permanent magnet and an electromagnet coil on a stator and (2) a rotor that includes a steel contact plate mounted, with tension spring loading, on an aluminum hub. The stator is mounted securely on a stationary object, which would ordinarily be the housing of a gear drive or a motor. The rotor is mounted on the shaft of the gear drive or motor. The commercial brake nominally operates in a fail-safe (in the sense of normally braking) mode: In the absence of current in the electromagnet coil, the permanent magnet pulls the contact plate, against the spring tension, into contact with the stator. To release the brake, one excites the electromagnet with a current of the magnitude and polarity chosen to cancel the magnetic flux of the permanent magnet, thereby enabling the spring tension to pull the contact plate out of contact with the stator. The fail-safe operation of the commercial brake depends on careful mounting of the rotor in relation to the stator. The rotor/stator gap must be set with a tolerance between 10 and 15 mils (between about 0.25 and about 0.38 mm). If the gap or the contact pad is thicker than the maximum allowable value, then the permanent magnetic field will not be strong enough to pull the steel plate across the gap. (For this reason, any contact pad between the contact plate and the stator must also be correspondingly thin.) If the gap exceeds the maximum allowable value because of shaft end play, it becomes impossible to set the brake by turning off the electromagnet current. Although it may still be possible to set the brake by applying an electromagnet current to aid the permanent magnetic field instead of canceling it, this action can mask an out-of-tolerance condition in the brake and it does not restore the fail-safe function of setting the brake when current is lost.

  8. Development of an Electric Motor Powered Low Cost Coconut Deshelling Machine

    NASA Astrophysics Data System (ADS)

    Mondal, Imdadul Hoque; Prasanna Kumar, G. V.

    2016-06-01

    An electric motor powered coconut deshelling machine was developed in line with the commercially available unit, but with slight modifications. The machine worked on the principle that the coconut shell can be caused to fail in shear and compressive forces. It consisted of a toothed wheel, a deshelling rod, an electric motor, and a compound chain drive. A bevelled 16 teeth sprocket with 18 mm pitch was used as the toothed wheel. Mild steel round bar of 18 mm diameter was used as the deshelling rod. The sharp edge tip of the deshelling rod was inserted below the shell to apply shear force on the shell, and the fruit was tilted toward the rotary toothed wheel to apply the compressive force on the shell. The speed of rotation of the toothed wheel was set at 34 ± 2 rpm. The output capacity of the machine was found to be 24 coconuts/h with 95 % of the total time effectively used for deshelling. The labour requirement was found to be 43 man-h/1000 nuts. About 13 % of the kernels got scraped and about 7 % got sliced during the operation. The developed coconut deshelling machine was recommended for the minimum annual use of 200 h or deshelling of 4700 coconuts per year. The cost of operation for 200 h of annual use was found to be about ` 47/h. The developed machine was found to be simple, easy to operate, energy efficient, safe and reduce drudgery involved in deshelling by conventional methods.

  9. Child maltreatment: pathway to chronic and long-term conditions?

    PubMed

    Taylor, Julie; Bradbury-Jones, Caroline; Lazenbatt, Anne; Soliman, Francesca

    2016-09-01

    The manifesto Start Well, Live Better by the UK Faculty of Public Health (Start Well, Live Better-A Manifesto for the Public's Health. London: UK Faculty of Public Health, 2014) sets out 12 compelling priorities for the protection of people's health. The focus of this document is preventative, calling for a comprehensive strategy to target a wide-ranging set of challenges to public health; however, it fails to mention child maltreatment and its negative impact on long-term health outcomes. In this article, we explore the long-term negative consequences of child maltreatment and how these can be conceptually aligned with four different characteristics of long-term health conditions. We suggest that situating child maltreatment within a long-term conditions framework could have significant advantages and implications for practice, policy and research, by strengthening a commitment across disciplines to apply evidence-based principles linked with policy and evaluation and recognizing the chronic effects of maltreatment to concentrate public, professional and government awareness of the extent and impact of the issue. We argue that a public health approach is the most effective way of focusing preventative efforts on the long-term sequelae of child maltreatment and to foster cooperation in promoting children's rights to grow and develop in a safe and caring environment free from violence and abuse. © The Author 2015. Published by Oxford University Press on behalf of Faculty of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  10. Addressing Control of Hazardous Energy (COHE) Requirements in a Laser Safety Program

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Woods, Michael; /SLAC

    OSHA regulation 29CFR1910.147 specifies control of hazardous energy requirements for 'the servicing and maintenance of machines and equipment in which the unexpected energization or start up of the machines or equipment, or release of stored energy could cause injury to employees.' Class 3B and Class 4 laser beams must be considered hazardous energy sources because of the potential for serious eye injury; careful consideration is therefore needed to safely de-energize these lasers. This paper discusses and evaluates control of hazardous energy principles in this OSHA regulation, in ANSI Z136.1 ''Safe Use of Lasers,'' and in ANSI Z244.1 ''Control of Hazardousmore » Energy, Lockout/Tagout and Alternative Methods.'' Recommendations are made for updating and improving CoHE (control of hazardous energy) requirements in these standards for their applicability to safe laser operations.« less

  11. Medicines optimisation: priorities and challenges.

    PubMed

    Kaufman, Gerri

    2016-03-23

    Medicines optimisation is promoted in a guideline published in 2015 by the National Institute for Health and Care Excellence. Four guiding principles underpin medicines optimisation: aim to understand the patient's experience; ensure evidence-based choice of medicines; ensure medicines use is as safe as possible; and make medicines optimisation part of routine practice. Understanding the patient experience is important to improve adherence to medication regimens. This involves communication, shared decision making and respect for patient preferences. Evidence-based choice of medicines is important for clinical and cost effectiveness. Systems and processes for the reporting of medicines-related safety incidents have to be improved if medicines use is to be as safe as possible. Ensuring safe practice in medicines use when patients are transferred between organisations, and managing the complexities of polypharmacy are imperative. A medicines use review can help to ensure that medicines optimisation forms part of routine practice.

  12. Environmental Management: the Ideology of Natural Resource Rational Use

    NASA Astrophysics Data System (ADS)

    Zolotukhin, V. M.; Gogolin, V. A.; Yazevich, M. Yu; Baumgarten, M. I.; Dyagileva, A. V.

    2017-01-01

    The article presents an analysis of the ontological and methodological principles of environmental management. These principles form the united ideology of natural resource rational use as the environment preservation basis. Consideration of environmental issues from the environmental management point of view is stipulated by the concern of the scientific community about the existence of mankind and the sphere of its inhabiting. The need to overcome the stereotypes existing in mass consciousness about safe and environmentally friendly consumption is stressed. The process of forming environmental management policy should contribute to the stabilization (balancing) of the consumers’ expectations and collective decision-making based on a public ecological consensus.

  13. Controlled drugs and the principle of double effect: the role of the district nurse.

    PubMed

    Griffith, Richard

    2016-12-02

    The role of district nurses in the effective management of pain in palliative care has been strengthened by the Misuse of Drugs (Amendment No.2) (England, Wales and Scotland) Regulations 2012 that allow district nurses who are independent or supplementary prescribers to prescribe and administer controlled drugs. However, prescribing controlled drugs brings increased responsibility and accountability for the safe management of these medicines. In this article Richard Griffith considers the principle of double effect that seeks to ensure that patients in intractable pain receive the analgesia they require to manage that pain while district nurses avoid liability and prosecution under the law of murder.

  14. Optimal Aircraft Control Upset Recovery With and Without Component Failures

    NASA Technical Reports Server (NTRS)

    Sparks, Dean W.; Moerder, Daniel D.

    2002-01-01

    This paper treats the problem of recovering sustainable nondescending (safe) flight in a transport aircraft after one or more of its control effectors fail. Such recovery can be a challenging goal for many transport aircraft currently in the operational fleet for two reasons. First, they have very little redundancy in their means of generating control forces and moments. These aircraft have, as primary control surfaces, a single rudder and pairwise elevators and aileron/spoiler units that provide yaw, pitch, and roll moments with sufficient bandwidth to be used in stabilizing and maneuvering the airframe. Beyond this, throttling the engines can provide additional moments, but on a much slower time scale. Other aerodynamic surfaces, such as leading and trailing edge flaps, are only intended to be placed in a position and left, and are, hence, very slow-moving. Because of this, loss of a primary control surface strongly degrades the controllability of the vehicle, particularly when the failed effector becomes stuck in a non-neutral position where it exerts a disturbance moment that must be countered by the remaining operating effectors. The second challenge in recovering safe flight is that these vehicles are not agile, nor can they tolerate large accelerations. This is of special importance when, at the outset of the recovery maneuver, the aircraft is flying toward the ground, as is frequently the case when there are major control hardware failures. Recovery of safe flight is examined in this paper in the context of trajectory optimization. For a particular transport aircraft, and a failure scenario inspired by an historical air disaster, recovery scenarios are calculated with and without control surface failures, to bring the aircraft to safe flight from the adverse flight condition that it had assumed, apparently as a result of contact with a vortex from a larger aircraft's wake. An effort has been made to represent relevant airframe dynamics, acceleration limits, and actuator limits faithfully, since these contribute to the lack of agility and control power that plays an important role in defining what can be achieved with the vehicle when it is in extremis.

  15. Obstetrical Practice and Training in Canadian Family Medicine: Conserving an Endangered Species

    PubMed Central

    Klein, Michael; Reynolds, J. L.; Boucher, Francois; Malus, Michael; Rosenberg, Ellen

    1984-01-01

    Family practice obstetricians are an endangered species. Our practices and teaching sites must provide the correct attitudinal as well as technical messages to result in a practitioner who will be able to meet the psychosocial and medical needs of the pregnant couple. Family practice obstetrics can be as safe as care given by obstetricians provided that the family practice group functions well, that obstetrical consultants are available and supportive, and assuming that technical approaches are reserved for those truly in need. In rural areas, obstetrical ability is essential, whilst in the urban setting it helps the family physician maintain a practice involving young families. Those trainees who fail to learn basic obstetrical skills (including family centered attitudes and approaches) may in any setting come to feel, belatedly, that their training programs failed in this respect. PMID:21279123

  16. Bardoxolone: augmenting the Yin in chronic kidney disease.

    PubMed

    Thomas, Merlin C

    2011-10-01

    Nrf-2 (NF-E2-related factor 2) is a regulator of anti-oxidant, anti-inflammatory and detoxification pathways. Coordinated augmentation of these key defence pathways via Nrf-2 signalling is being investigated for the treatment of chronic diseases, including diabetes and its complications. The first to reach commercial development is the triterpenoid, bardoxolone methyl. In recent clinical trial, bardoxolone rapidly improved kidney function on average by 5-10 ml/min within 4 weeks of therapy. Importantly, this improvement was sustained during one year of active treatment. This suggests that rather that overworking a failing system, bardoxolone appeared to safely augment renal function, at least to one year. If similar improvements in kidney function can be reproduced in the upcoming BEACON trial, it will represent a major advance on conventional therapy and new way to bring balance to the failing kidney.

  17. Space shuttle environmental control/life support systems

    NASA Technical Reports Server (NTRS)

    1972-01-01

    This study analyzes and defines a baseline Environmental Control/Life Support System (EC/LSS) for a four-man, seven-day orbital shuttle. In addition, the impact of various mission parameters, crew size, mission length, etc. are examined for their influence on the selected system. Pacing technology items are identified to serve as a guide for application of effort to enhance the total system optimization. A fail safe-fail operation philosophy was utilized in designing the system. This has resulted in a system that requires only one daily routine operation. All other critical item malfunctions are automatically resolved by switching to redundant modes of operation. As a result of this study, it is evident that a practical, flexible, simple and long life, EC/LSS can be designed and manufactured for the shuttle orbiter within the time phase required.

  18. Robust extraction of the aorta and pulmonary artery from 3D MDCT image data

    NASA Astrophysics Data System (ADS)

    Taeprasartsit, Pinyo; Higgins, William E.

    2010-03-01

    Accurate definition of the aorta and pulmonary artery from three-dimensional (3D) multi-detector CT (MDCT) images is important for pulmonary applications. This work presents robust methods for defining the aorta and pulmonary artery in the central chest. The methods work on both contrast enhanced and no-contrast 3D MDCT image data. The automatic methods use a common approach employing model fitting and selection and adaptive refinement. During the occasional event that more precise vascular extraction is desired or the method fails, we also have an alternate semi-automatic fail-safe method. The semi-automatic method extracts the vasculature by extending the medial axes into a user-guided direction. A ground-truth study over a series of 40 human 3D MDCT images demonstrates the efficacy, accuracy, robustness, and efficiency of the methods.

  19. Classroom Learning Environment & Student Motivational Differences between Exemplary, Recognized, & Acceptable Urban Middle Level Schools

    ERIC Educational Resources Information Center

    Waxman, Hersh C.; Garcia, Andres; Read, Lisa L.

    2008-01-01

    One of the essential principles for improving middle grade education is to establish a safe and healthy school environment (Jackson & Davis, 2000; Price & Waxman, 2005). The overall quality of the school climate or school environment has been argued to be one of the central problems of urban schools (Waxman & Huang, 1997). Several…

  20. Carpenter: Apprenticeship Course Outline. Apprenticeship and Industry Training. 0207.1

    ERIC Educational Resources Information Center

    Alberta Advanced Education and Technology, 2007

    2007-01-01

    The graduate of the Carpenter apprenticeship program is a certified journeyperson who will be able: (1) to responsibly do all work tasks expected of a journeyperson; (2) to supervise, train and coach apprentices; (3) to understand the principles of sound and safe construction; (4) to know the characteristics and proper use of all building…

  1. Putting It All Together: Guiding Principles for Quality After-School Programs Serving Preteens

    ERIC Educational Resources Information Center

    Metz, Rachel A.; Goldsmith, Julie; Arbreton, Amy J. A.

    2008-01-01

    Successfully navigating early adolescence depends, in large part, on the availability of safe and engaging activities and supportive relationships with adults, yet many preteens have limited access to positive supports and opportunities such as high-quality after-school programs that could put them on a path to success. Funders, policymakers and…

  2. Demonstration and Research Pest Control: A Training Program for the Certification of Pesticide Applicators, Manual No. 10.

    ERIC Educational Resources Information Center

    Rust, Harry K.; And Others

    This manual is intended to provide the information necessary to meet EPA standards for demonstration and research pest control and prepare for the written examination required for certification. Emphasis is placed on the principles of safe pesticide use. Chapters are included on pesticide applicator certification in Virginia, basics of pest…

  3. Basic Principles--Outdoor Living Skills Series. Instructor Manual.

    ERIC Educational Resources Information Center

    Deaton, Don

    The priorities for sustaining life--air, shelter, water, and food--are the subjects of this module designed to give junior and senior high school students the foundation for safe, rewarding experiences in the outdoors. Five 50-minute lesson plans cover the basic need in order of priority: air (3 minutes to survive without it), shelter (3 hours, in…

  4. Locksmith: Apprenticeship Course Outline. Apprenticeship and Industry Training. 5008.1

    ERIC Educational Resources Information Center

    Alberta Advanced Education and Technology, 2008

    2008-01-01

    The graduate of the Locksmith apprenticeship program is a certified journeyperson who will be able to: (1) apply the principles of Locksmithing; (2) handle orders of locks, safes and allied equipment; (3) operate and service the tools and machinery as used in the Locksmith trade; (4) perform the installation of locks and allied equipment; (5)…

  5. One-stage dorsal lingual mucosal graft urethroplasty for the treatment of failed hypospadias repair.

    PubMed

    Li, Hong-Bin; Xu, Yue-Min; Fu, Qiang; Sa, Ying-Long; Zhang, Jiong; Xie, Hong

    2016-01-01

    The aim of this study was to retrospectively investigate the outcomes of patients who underwent one-stage onlay or inlay urethroplasty using a lingual mucosal graft (LMG) after failed hypospadias repairs. Inclusion criteria included a history of failed hypospadias repair, insufficiency of the local skin that made a reoperation with skin flaps difficult, and necessity of an oral mucosal graft urethroplasty. Patients were excluded if they had undergone a failed hypospadias repair using the foreskin or a multistage repair urethroplasty. Between January 2008 and December 2012, 110 patients with failed hypospadias repairs were treated in our center. Of these patients, 56 underwent a one-stage onlay or inlay urethroplasty using LMG. The median age was 21.8 years (range: 4-45 years). Of the 56 patients, one-stage onlay LMG urethroplasty was performed in 42 patients (group 1), and a modified Snodgrass technique using one-stage inlay LMG urethroplasty was performed in 14 (group 2). The median LMG urethroplasty length was 5.6 ± 1.6 cm (range: 4-13 cm). The mean follow-up was 34.7 months (range: 10-58 months), and complications developed in 12 of 56 patients (21.4%), including urethrocutaneous fistulas in 7 (6 in group 1, 1 in group 2) and neourethral strictures in 5 (4 in group 1, 1 in group 2). The total success rate was 78.6%. Our survey suggests that one-stage onlay or inlay urethroplasty with LMG may be an effective option to treat the patients with less available skin after failed hypospadias repairs; LMG harvesting is easy and safe, irrespective of the patient's age.

  6. Design Optimization of Composite Structures under Uncertainty

    NASA Technical Reports Server (NTRS)

    Haftka, Raphael T.

    2003-01-01

    Design optimization under uncertainty is computationally expensive and is also challenging in terms of alternative formulation. The work under the grant focused on developing methods for design against uncertainty that are applicable to composite structural design with emphasis on response surface techniques. Applications included design of stiffened composite plates for improved damage tolerance, the use of response surfaces for fitting weights obtained by structural optimization, and simultaneous design of structure and inspection periods for fail-safe structures.

  7. ARE660 Wind Generator: Low Wind Speed Technology for Small Turbine Development

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Robert W. Preus; DOE Project Officer - Keith Bennett

    2008-04-23

    This project is for the design of a wind turbine that can generate most or all of the net energy required for homes and small businesses in moderately windy areas. The purpose is to expand the current market for residential wind generators by providing cost effective power in a lower wind regime than current technology has made available, as well as reduce noise and improve reliability and safety. Robert W. Preus’ experience designing and/or maintaining residential wind generators of many configurations helped identify the need for an improved experience of safety for the consumer. Current small wind products have unreliablemore » or no method of stopping the wind generator in fault or high wind conditions. Consumers and their neighbors do not want to hear their wind generators. In addition, with current technology, only sites with unusually high wind speeds provide payback times that are acceptable for the on-grid user. Abundant Renewable Energy’s (ARE) basic original concept for the ARE660 was a combination of a stall controlled variable speed small wind generator and automatic fail safe furling for shutdown. The stall control for a small wind generator is not novel, but has not been developed for a variable speed application with a permanent magnet alternator (PMA). The fail safe furling approach for shutdown has not been used to our knowledge.« less

  8. CSF Lumbar Drainage: A Safe Surgical Option in Refractory Intracranial Hypertension Associated with Acute Posttraumatic External Hydrocephalus.

    PubMed

    Manet, R; Schmidt, E A; Vassal, F; Charier, D; Gergelé, L

    2016-01-01

    External lumbar drainage (ELD) of cerebrospinal fluid (CSF) in posttraumatic refractory intracranial hypertension (ICHT) is controversial. We report our experience of ELD in ICHT associated with acute disturbance of CSF flow within subarachnoid spaces (SASs). Four adult patients admitted to the neurointensive care unit for severe TBI who presented with secondary ICHT are retrospectively reported. When refractory to second-tier therapy, if external ventricular drainage were not possible or failed, and in the absence of an indication for craniotomy to treat a mass lesion or decompressive craniectomy, we assessed the evolution of CSF volume within cranial SAS and checked the presence of basal cisterns and the absence of tonsillar herniation to evaluate interest in and the safety of ELD. As second-tier therapy failed to lower intracranial pressure (ICP; mean ICP 37 ± 5 mmHg), and computed tomography (CT) showed abnormally enlarged cranial SAS following traumatic subarachnoid hemorrhage, patients received ELD. ICP decreased, with immediate and long-term effect (mean ICP 5 mmHg ± 2 mmHg). There were no complications to report. Acute traumatic external hydrocephalus may explain some of the specific situations of secondary increased ICP, with a "normal" CT scan, that is refractory to medical treatment. In these situations, lumbar drainage should be considered to be a safe, minimally invasive, and effective surgical option.

  9. Magnetic fluid control for viscous loss reduction of high-speed MRF brakes and clutches with well-defined fail-safe behavior

    NASA Astrophysics Data System (ADS)

    Güth, Dirk; Schamoni, Markus; Maas, Jürgen

    2013-09-01

    No-load losses within brakes and clutches based on magnetorheological fluids are unavoidable and represent a major barrier towards their wide-spread commercial adoption. Completely torque free rotation is not yet possible due to persistent fluid contact within the shear gap. In this paper, a novel concept is presented that facilitates the controlled movement of the magnetorheological fluid from an active, torque-transmitting region into an inactive region of the shear gap. This concept enables complete decoupling of the fluid engaging surfaces such that viscous drag torque can be eliminated. In order to achieve the desired effect, motion in the magnetorheological fluid is induced by magnetic forces acting on the fluid, which requires an appropriate magnetic circuit design. In this investigation, we propose a methodology to determine suitable magnetic circuit designs with well-defined fail-safe behavior. The magnetically induced motion of magnetorheological fluids is modeled by the use of the Kelvin body force, and a multi-physics domain simulation is performed to elucidate various transitions between an engaged and disengaged operating mode. The modeling approach is validated by captured high-speed video frames which show the induced motion of the magnetorheological fluid due to the magnetic field. Finally, measurements performed with a prototype actuator prove that the induced viscous drag torque can be reduced significantly by the proposed magnetic fluid control methodology.

  10. Risk Assessment and Hierarchical Risk Management of Enterprises in Chemical Industrial Parks Based on Catastrophe Theory

    PubMed Central

    Chen, Yu; Song, Guobao; Yang, Fenglin; Zhang, Shushen; Zhang, Yun; Liu, Zhenyu

    2012-01-01

    According to risk systems theory and the characteristics of the chemical industry, an index system was established for risk assessment of enterprises in chemical industrial parks (CIPs) based on the inherent risk of the source, effectiveness of the prevention and control mechanism, and vulnerability of the receptor. A comprehensive risk assessment method based on catastrophe theory was then proposed and used to analyze the risk levels of ten major chemical enterprises in the Songmu Island CIP, China. According to the principle of equal distribution function, the chemical enterprise risk level was divided into the following five levels: 1.0 (very safe), 0.8 (safe), 0.6 (generally recognized as safe, GRAS), 0.4 (unsafe), 0.2 (very unsafe). The results revealed five enterprises (50%) with an unsafe risk level, and another five enterprises (50%) at the generally recognized as safe risk level. This method solves the multi-objective evaluation and decision-making problem. Additionally, this method involves simple calculations and provides an effective technique for risk assessment and hierarchical risk management of enterprises in CIPs. PMID:23208298

  11. Safety Early Warning Research for Highway Construction Based on Case-Based Reasoning and Variable Fuzzy Sets

    PubMed Central

    Liu, Yan; Xu, Zhen-Jun

    2013-01-01

    As a high-risk subindustry involved in construction projects, highway construction safety has experienced major developments in the past 20 years, mainly due to the lack of safe early warnings in Chinese construction projects. By combining the current state of early warning technology with the requirements of the State Administration of Work Safety and using case-based reasoning (CBR), this paper expounds on the concept and flow of highway construction safety early warnings based on CBR. The present study provides solutions to three key issues, index selection, accident cause association analysis, and warning degree forecasting implementation, through the use of association rule mining, support vector machine classifiers, and variable fuzzy qualitative and quantitative change criterion modes, which fully cover the needs of safe early warning systems. Using a detailed description of the principles and advantages of each method and by proving the methods' effectiveness and ability to act together in safe early warning applications, effective means and intelligent technology for a safe highway construction early warning system are established. PMID:24191134

  12. Safety early warning research for highway construction based on case-based reasoning and variable fuzzy sets.

    PubMed

    Liu, Yan; Yi, Ting-Hua; Xu, Zhen-Jun

    2013-01-01

    As a high-risk subindustry involved in construction projects, highway construction safety has experienced major developments in the past 20 years, mainly due to the lack of safe early warnings in Chinese construction projects. By combining the current state of early warning technology with the requirements of the State Administration of Work Safety and using case-based reasoning (CBR), this paper expounds on the concept and flow of highway construction safety early warnings based on CBR. The present study provides solutions to three key issues, index selection, accident cause association analysis, and warning degree forecasting implementation, through the use of association rule mining, support vector machine classifiers, and variable fuzzy qualitative and quantitative change criterion modes, which fully cover the needs of safe early warning systems. Using a detailed description of the principles and advantages of each method and by proving the methods' effectiveness and ability to act together in safe early warning applications, effective means and intelligent technology for a safe highway construction early warning system are established.

  13. Identification and Reconfigurable Control of Impaired Multi-Rotor Drones

    NASA Technical Reports Server (NTRS)

    Stepanyan, Vahram; Krishnakumar, Kalmanje; Bencomo, Alfredo

    2016-01-01

    The paper presents an algorithm for control and safe landing of impaired multi-rotor drones when one or more motors fail simultaneously or in any sequence. It includes three main components: an identification block, a reconfigurable control block, and a decisions making block. The identification block monitors each motor load characteristics and the current drawn, based on which the failures are detected. The control block generates the required total thrust and three axis torques for the altitude, horizontal position and/or orientation control of the drone based on the time scale separation and nonlinear dynamic inversion. The horizontal displacement is controlled by modulating the roll and pitch angles. The decision making algorithm maps the total thrust and three torques into the individual motor thrusts based on the information provided by the identification block. The drone continues the mission execution as long as the number of functioning motors provide controllability of it. Otherwise, the controller is switched to the safe mode, which gives up the yaw control, commands a safe landing spot and descent rate while maintaining the horizontal attitude.

  14. Anaesthesia and global health initiatives for children in a low-resource environment.

    PubMed

    Hodges, Sarah C

    2016-06-01

    As the United Nations moves from Millennium Development Goals to Sustainable Development Goals, we find ourselves with the opportunity to influence the priority of global health initiatives. Previously, the global health community has failed to recognise the importance of access to safe, affordable surgery and developing the necessary specialities that support it as most of the funding focus had been on primary healthcare and infectious diseases. Now the WHO is publishing guidelines to safe surgery and the Lancet Commission on Global Surgery has been launched. However, this is only the start; anaesthesia remains a forgotten speciality within the world of public and global health and there are still challenges in escalating surgery in low and middle-income countries to an acceptable level that is affordable and timely. Although there is increased world interest in safe surgery and anaesthesia this has not yet been translated into a mandate that will compel countries to invest in improving levels of infrastructure, accessibility, manpower, and safety. A general anaesthetic remains a dangerous event in a child's life in resource-limited countries.

  15. Special Forces Values: How The Regiment’s Ethical Framework Influences Its Organizational Effectiveness

    DTIC Science & Technology

    2017-12-01

    Stated another way, one might feel less culpable for (a) failing to act when 8 Louis Pojman, Ethics...effectiveness. Rather, I mean that these schemata may have probabilistic predictive power when applied broadly, to groups or organizations rather than to...fundamental rights of the American people to national independence and sovereignty are principles derived from the above “self-evident truths.” These

  16. After 2015: The Next Security Era for Britain

    DTIC Science & Technology

    2012-03-01

    Defence Committee hearings , the population and its key communicators are measurably unconvinced about the necessity, success, and professionalism... immigrants the public can see that al Qaeda is faltering, and that for several years it has failed to grab the front-page space that it strives...is in principle systemic; without effective internal bor- ders, refugees landing in Italy, Spain , or Greece from the sea have comparative freedom of

  17. F-15 HiDEC in flight over Mojave desert

    NASA Technical Reports Server (NTRS)

    1990-01-01

    NASA's F-15 HIDEC (Highly Integrated Digital Electronic Control) research aircraft cruises over California's Mojave Desert at sunset on a flight out of the Dryden Flight Research Center, Edwards, California. The aircraft was used to carry out research on engine and flight control systems and most recently demonstrated the use of computer-assisted engine controls as a means of landing an aircraft safely with only engine power if its normal control surfaces such as elevators, rudders or ailerons are disabled. The aircraft also tested and evaluated a computerized self-repair flight control system for the Air Force that detects damaged or failed flight control surfaces, and then reconfigures undamaged flight surfaces so the mission can continue or the aircraft is landed safely. Nearly all research being carried out in the HIDEC program is applicable to future civilian and military aircraft.

  18. Fracture strength of flawed cylindrical pressure vessels under cryogenic temperatures

    NASA Astrophysics Data System (ADS)

    Christopher, T.; Sankarnarayanasamy, K.; Nageswara Rao, B.

    2002-11-01

    Damage tolerant and fail-safe approaches have been employed increasingly in the design of critical engineering components. In these approaches, one has to assess the residual strength of a component with an assumed pre-existing crack. In other cases, cracks may be detected during service. Then, there is a need to evaluate the residual strength of the cracked components in order to decide whether they can be continued safely or repair and replacement are imperative. A three-parameter fracture criterion is applied to correlate the fracture data on aluminium, titanium and steel materials from test results on cylindrical tanks/pressure vessels at cryogenic temperatures. Fracture parameters to generate the failure assessment diagram are determined for the materials considered in the present study. Failure pressure estimates were found to be in good agreement with test results.

  19. Microbial quality of improved drinking water sources: evidence from western Kenya and southern Vietnam.

    PubMed

    Grady, Caitlin A; Kipkorir, Emmanuel C; Nguyen, Kien; Blatchley, E R

    2015-06-01

    In recent decades, more than 2 billion people have gained access to improved drinking water sources thanks to extensive effort from governments, and public and private sector entities. Despite this progress, many water sector development interventions do not provide access to safe water or fail to be sustained for long-term use. The authors examined drinking water quality of previously implemented water improvement projects in three communities in western Kenya and three communities in southern Vietnam. The cross-sectional study of 219 households included measurements of viable Escherichia coli. High rates of E. coli prevalence in these improved water sources were found in many of the samples. These findings suggest that measures above and beyond the traditional 'improved source' definition may be necessary to ensure truly safe water throughout these regions.

  20. Individuation in Quantum Mechanics and Space-Time

    NASA Astrophysics Data System (ADS)

    Jaeger, Gregg

    2010-10-01

    Two physical approaches—as distinct, under the classification of Mittelstaedt, from formal approaches—to the problem of individuation of quantum objects are considered, one formulated in spatiotemporal terms and one in quantum mechanical terms. The spatiotemporal approach itself has two forms: one attributed to Einstein and based on the ontology of space-time points, and the other proposed by Howard and based on intersections of world lines. The quantum mechanical approach is also provided here in two forms, one based on interference and another based on a new Quantum Principle of Individuation (QPI). It is argued that the space-time approach to individuation fails and that the quantum approach offers several advantages over it, including consistency with Leibniz’s Principle of Identity of Indiscernibles.

  1. The safe disposal of radioactive wastes

    PubMed Central

    Kenny, A. W.

    1956-01-01

    A comprehensive review is given of the principles and problems involved in the safe disposal of radioactive wastes. The first part is devoted to a study of the basic facts of radioactivity and of nuclear fission, the characteristics of radioisotopes, the effects of ionizing radiations, and the maximum permissible levels of radioactivity for workers and for the general public. In the second part, the author describes the different types of radioactive waste—reactor wastes and wastes arising from the use of radioisotopes in hospitals and in industry—and discusses the application of the maximum permissible levels of radioactivity to their disposal and treatment, illustrating his discussion with an account of the methods practised at the principal atomic energy establishments. PMID:13374534

  2. Special care dentistry for general dental practice.

    PubMed

    Greig, Vicki; Sweeney, Petrina

    2013-01-01

    Although special care dentistry (SCD) is a fairly recent specialty, the principles and practice of SCD have been developed since the 1980s. Shared care of these patients with general dental practitioners remains vital to ensure that comprehensive care is provided. This article aims to discuss some of the patient groups commonly seen in SCD clinics and give an insight into the varied complex medical and social aspects of care which are managed as part of providing appropriate, safe and holistic care. Many patients who currently fall under the remit of special care dentistry could be treated safely in general dental practice. This article acts as an introduction to special care dentistry for general dental practitioners.

  3. Can Youthful Students be Encouraged to Self-repair Damaged Vision Using Elementary Mathematics and Physics Principles?

    NASA Astrophysics Data System (ADS)

    Ferreira, Nadja; McLeod, Roger

    2006-03-01

    Safe and easy self-repair of damaged vision in youth, detected from squinted eyes, motivated by simple applied math and physics, and over-stretched elastics. Parental permission and participation, with math skills of numerical cancellation, bring physics understanding to students. They recognize pupil diameter changes with light intensity. Ideas of focal surfaces and wavelength dependence can be achieved by burning paper with a magnifying glass, and dispersing light with a prism. Safeness of eye and head movements required are like those of the mother in applying makeup, or of a father in shaving. Easily defined, performed and monitored visual tasks can complete the repair(s).

  4. Nine key principles to guide youth mental health: development of service models in New South Wales.

    PubMed

    Howe, Deborah; Batchelor, Samantha; Coates, Dominiek; Cashman, Emma

    2014-05-01

    Historically, the Australian health system has failed to meet the needs of young people with mental health problems and mental illness. In 2006, New South Wales (NSW) Health allocated considerable funds to the reform agenda of mental health services in NSW to address this inadequacy. Children and Young People's Mental Health (CYPMH), a service that provides mental health care for young people aged 12-24 years, with moderate to severe mental health problems, was chosen to establish a prototype Youth Mental Health (YMH) Service Model for NSW. This paper describes nine key principles developed by CYPMH to guide the development of YMH Service Models in NSW. A literature review, numerous stakeholder consultations and consideration of clinical best practice were utilized to inform the development of the key principles. Subsequent to their development, the nine key principles were formally endorsed by the Mental Health Program Council to ensure consistency and monitor the progress of YMH services across NSW. As a result, between 2008 and 2012 YMH Services across NSW regularly reported on their activities against each of the nine key principles demonstrating how each principle was addressed within their service. The nine key principles provide mental health services a framework for how to reorient services to accommodate YMH and provide a high-quality model of care. [Corrections added on 29 November 2013, after first online publication: The last two sentences of the Results section have been replaced with "As a result, between 2008 and 2012 YMH Services across NSW regularly reported on their activities against each of the nine key principles demonstrating how each principle was addressed within their service."]. © 2013 Wiley Publishing Asia Pty Ltd.

  5. A critique of the principle of 'respect for autonomy', grounded in African thought.

    PubMed

    Behrens, Kevin G

    2018-06-01

    I give an account how the principle of 'respect for autonomy' dominates the field of bioethics, and how it came to triumph over its competitors, 'respect for persons' and 'respect for free power of choice'. I argue that 'respect for autonomy' is unsatisfactory as a basic principle of bioethics because it is grounded in too individualistic a worldview, citing concerns of African theorists and other communitarians who claim that the principle fails to acknowledge the fundamental importance of understanding persons within the nexus of their communal relationships. I defend the claim that 'respect for persons' is a more appropriate principle, as it is able to acknowledge both individual decision making and the essential relationality of persons. I acknowledge that my preference for 'respect for persons' is problematic because of the important debate around the definition of 'personhood' in bioethics discourse. Relying on Thaddeus Metz's conception of moral status, I propose a relational definition of personhood that distinguishes between persons with agency and persons without agency, arguing that we have different moral obligations to these distinct categories of persons. I claim that this conception of personhood is better able to accommodate our moral intuitions than conventional approaches, and that it is able to do so without being speciesist or question-begging. © 2017 John Wiley & Sons Ltd.

  6. Simulating fuel treatment effects in dry forests of the western United States: testing the principles of a fire-safe forest

    Treesearch

    Morris C. Johnson; Maureen C Kennedy; David L. Peterson

    2011-01-01

    We used the Fire and Fuels Extension to the Forest Vegetation Simulator (FFE-FVS) to simulate fuel treatment effects on stands in low- to midelevation dry forests (e.g., ponderosa pine (Pinus ponderosa Dougl. ex. P. & C. Laws.) and Douglas-fir (Pseudotsuga menziesii (Mirb.) Franco) of the western United States. We...

  7. "Use Condoms for Safe Sex!" Youth-Led Video Making and Sex Education

    ERIC Educational Resources Information Center

    Yang, Kyung-Hwa; MacEntee, Katie

    2015-01-01

    Situated at the intersection between child-led visual methods and sex education, this paper focuses on the potential of youth-led video making to enable young people to develop guiding principles to inform their own sexual behaviour. It draws on findings from a video-making project carried out with a group of South African young people, which…

  8. Physical Activity Promotion in Schools: Which Strategies Do Schools (Not) Implement and Which Socioecological Factors Are Associated with Implementation?

    ERIC Educational Resources Information Center

    Cardon, Greet M.; Van Acker, Ragnar; Seghers, Jan; De Martelaer, Kristine; Haerens, Leen L.; De Bourdeaudhuij, Ilse M. M.

    2012-01-01

    We studied the implementation and associated factors of strategies (e.g. sports after school and during lunch break, active schoolyards, active school commuting) and organizational principles (e.g. safe bike racks, pupil involvement) that facilitate the physical activity (PA)-promoting role of schools. Key representatives of 111 elementary and 125…

  9. 3 CFR 8590 - Proclamation 8590 of October 29, 2010. Military Family Month, 2010

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... October 29, 2010 Proc. 8590 Military Family Month, 2010By the President of the United States of America A... exemplify the highest principles of our Nation. Across America, military families inspire us all with their... us safe and free. As America asks ever more of military families, they have a right to expect more of...

  10. Advanced Technologies in Safe and Efficient Operating Rooms

    DTIC Science & Technology

    2009-02-01

    parameters and sitting strategies to determine car seat design that is both comfortable and ergonomically sound.8 The study of ergonomics in the surgical...off stereo into a prototype endoscope and developed design concepts for visualization techniques based on principles of cognitive ergonomics ...results from simultaneous task performance—is typical of knowledge ascertained through ergonomic clinical research.6 Ergonomic theory, design , and

  11. Understanding practitioner professionalism in Aboriginal and Torres Strait Islander health: lessons from student and registrar placements at an urban Aboriginal and Torres Strait Islander primary healthcare service.

    PubMed

    Askew, Deborah A; Lyall, Vivian J; Ewen, Shaun C; Paul, David; Wheeler, Melissa

    2017-10-01

    Aboriginal and Torres Strait Islander peoples continue to be pathologised in medical curriculum, leaving graduates feeling unequipped to effectively work cross-culturally. These factors create barriers to culturally safe health care for Aboriginal and Torres Strait Islander peoples. In this pilot pre-post study, the learning experiences of seven medical students and four medical registrars undertaking clinical placements at an urban Aboriginal and Torres Strait Islander primary healthcare service in 2014 were followed. Through analysis and comparison of pre- and post-placement responses to a paper-based case study of a fictitious Aboriginal patient, four learning principles for medical professionalism were identified: student exposure to nuanced, complex and positive representations of Aboriginal peoples; positive practitioner role modelling; interpersonal skills that build trust and minimise patient-practitioner relational power imbalances; and knowledge, understanding and skills for providing patient-centred, holistic care. Though not exhaustive, these principles can increase the capacity of practitioners to foster culturally safe and optimal health care for Aboriginal peoples. Furthermore, competence and effectiveness in Aboriginal health care is an essential component of medical professionalism.

  12. Fail-Safe Pressure Plug

    NASA Technical Reports Server (NTRS)

    Svejkovsky, Paul A.

    1993-01-01

    Protective plug resists slowly built-up pressure or automatically releases itself if pressure rises suddenly. Seals out moisture at pressures ranging from 50 micrometers of mercury to 200 pounds per square inch. Designed to seal throat of 38 Reaction Control Thrusters on Space Shuttle protecting internal components from corrosion. Plug conforms to contour of nozzle throat, where O-ring forms pressure seal. After plug inserted, cover attached by use of cover-fitting assembly. Modified versions useful in protecting engines, pumps, reaction vessels, and other industrial equipment during shipment and maintenance.

  13. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Masala, Salvatore; Roselli, Mario; Manenti, Guglielmo

    A 70-year-old man with a painful vertebral metastasis was treated with combined percutaneous cryoablation and vertebroplasty therapy (CVT) in one session. The patient was suffering from diffuse visceral metastasized cholangiocarcinoma. After several weeks of back pain, magnetic resonance imaging documented a single L2 bone metastasis. In consultation with the oncologists, palliative combined CVT was administered with the aim of obtaining pain relief and bone stabilization. In our experience this combined treatment is safe and effective for immediate pain relief in painful bone metastases when other standard palliative treatments have failed.

  14. Towards a Fail-Safe Air Force Culture: Creating a Resilient Future While Avoiding Past Mistakes

    DTIC Science & Technology

    2011-02-16

    for either preventing catastrophic failures or in the event they occur. The Air Force Safety process often uses the ― Swiss Cheese ‖ model to...evaluate accidents. The image of holes in the protective cheese layers (proactive and reactive measures) lining up in such a way as to allow an accident is... cheese . More importantly, however, a HRO‘s focus is on ―the process of the slices lining up as each moment where one hole aligns with another

  15. A View From Space. NASA Systems Engineering and Test

    DTIC Science & Technology

    2014-12-01

    rocket ship called Atlantis came alive. Technology was ubiquitous. There were so many critical components that had to be harmonized. If it weren’t for...notwithstanding any other provision of law, no person shall be subject to a penalty for failing to comply with a collection of information if it does not display a...July 8, 2011, affirmed whether every key compo- nent could safely “go for launch.” If any component operated outside its performance enve- lope

  16. Turkey: Background and U.S. Relations In Brief

    DTIC Science & Technology

    2017-03-21

    Zones,” Voice of America, March 8, 2017. 14 Ibid; Liz Sly, “Turkey’s Erdogan wants to establish a safe zone in the ISIS capital Raqqa,” Washington Post...Al Bab, a key transport hub in northern Syria that had been controlled since 2014 by the Islamic State. President Erdogan consistently refers to...the aftermath of the July 2016 failed coup), Erdogan may opt to seek closer relations with Russia, possibly at the expense of Turkey’s long-term ties

  17. An Analysis of the Concurrent Certification Program at Fleet Readiness Center Southwest

    DTIC Science & Technology

    2009-12-01

    Mapping  5S Methodology  Kanban  Poka - yoke  A3 Problem Solving  Single Point Lesson Plans (SPLP)  Total Productive Maintenance (TPM) 54 What...the actual demand of the customers. Kanban is as a demand signal which immediately propagates through the supply chain. D. POKA - YOKE : A Japanese...term that means "fail-safing" or "mistake- proofing." Avoiding (yokeru) inadvertent errors ( poka ) is a behavior-shaping constraint, or a method of

  18. Impulse Flashover Tests at Edgar Beauchamp High Voltage Test Facility, Dixon, California, in Support of Cutler Insulator Failure Investigation

    DTIC Science & Technology

    2006-07-01

    sites. The strength member of the safety core insulators is a fiberglass belt wrapped around pins in the end fittings. Porcelain tubes cover the belt... porcelain tube and heavily tracked the fiberglass belt but left the belt intact structurally (Figure 1). Figure 1. Cutler safety core insulator ...fail-safe insulators . For these tests, the porcelain tube of the safety core insulator was replaced with a plastic see-through tube. The test report [5

  19. Failure Investigation of a Cage Suspension Gear Chain used in Coal Mines

    NASA Astrophysics Data System (ADS)

    Ghosh, Debashis; Dutta, Shamik; Shukla, Awdhesh Kumar; Roy, Himadri

    2016-10-01

    This investigation is primarily aimed to examine the probable causes of in-service failure of cage suspension gear chain used in coal mines. Preliminary visual examination, dimensional measurement, chemical analysis, magnetic particle inspection and estimation of mechanical properties are necessary supplement to this investigation. Optical microscopic analysis along with scanning electron microscopy examinations are carried out to understand the metallurgical reasons for failure. The visual examination and magnetic particle investigations reveal presence of fissure cracks at weld joint for both un-failed and failed end link chain. The average hardness value has been found to increase gradually with the distance from the weld interface. The macro and microstructural examinations of the samples prepared from both failed and un-failed specimens depict presence of continuous as well as aligned linear inclusions randomly distributed along with decarburized layer at weld interface/fusion zone. Fractographic examination shows flat fracture covering major portion of cross-section, which is surrounded by a narrow annular metallic fracture surface having a texture different from that of the remaining surface. Fracture mechanics principles have been used to study the fatigue crack growth rate in both weld region and base region of the un-failed gear chain material. Detailed stress analyses are also carried out to evaluate the stress generated along the chain periphery. Finally, it is concluded that presence of serious weld defect due to use of improper welding parameters/procedure caused failure of the end links of the investigated chain link.

  20. Cocklebur (Xanthium strumarium, L. var. strumarium) intoxication in swine: review and redefinition of the toxic principle.

    PubMed

    Stuart, B P; Cole, R J; Gosser, H S

    1981-05-01

    Cocklebur (Xanthium strumarium) fed to feeder pigs was associated with acute to subacute hepatotoxicosis. Cotyledonary seedings fed at 0.75% to 3% of body weight or ground bur fed at 20% to 30% of the ration caused acute depression, convulsions, and death. Principle gross lesions were marked serofibrinous ascites, edema of the gallbladder wall, and lobular accentuation of the liver. Acute to subacute centrilobular hepatic necrosis was present microscopically. The previously reported toxic principle, hydroquinone, was not recovered from the plant or bur of X. strumarium. Authentic hydroquinone administered orally failed to produce lesions typical of cocklebur intoxication but did produce marked hyperglycemia. Carboxyatractyloside recovered from the aqueous extract of X. strumarium and authentic carboxyatractyloside, when fed to pigs, caused signs and lesions typical of cocklebur intoxication. Marked hypoglycemia and elevated serum glutamic oxaloacetic transaminase and serum isocitric dehydrogenase concentrations occurred in pigs with acute hepatic necrosis that had received either cocklebur seedlings, ground bur or carboxyatractyloside.

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