40 CFR 147.3010 - Mechanical integrity tests.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 22 2010-07-01 2010-07-01 false Mechanical integrity tests. 147.3010..., Ute Mountain Ute, and All Other New Mexico Tribes § 147.3010 Mechanical integrity tests. The... a pressure test, using liquid or gas that clearly demonstrates that mechanical integrity exists at...
40 CFR 146.8 - Mechanical integrity.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 22 2010-07-01 2010-07-01 false Mechanical integrity. 146.8 Section...) UNDERGROUND INJECTION CONTROL PROGRAM: CRITERIA AND STANDARDS General Provisions § 146.8 Mechanical integrity. (a) An injection well has mechanical integrity if: (1) There is no significant leak in the casing...
40 CFR 147.3109 - Timing of mechanical integrity test.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 22 2010-07-01 2010-07-01 false Timing of mechanical integrity test... Certain Oklahoma Indian Tribes § 147.3109 Timing of mechanical integrity test. The demonstrations of mechanical integrity required by § 146.14(b)(2) of this chapter prior to approval for the operation of a...
40 CFR 147.3107 - Mechanical integrity.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 22 2010-07-01 2010-07-01 false Mechanical integrity. 147.3107 Section 147.3107 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS... Oklahoma Indian Tribes § 147.3107 Mechanical integrity. (a) Monitoring of annulus pressure conducted...
40 CFR 68.73 - Mechanical integrity.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 16 2014-07-01 2014-07-01 false Mechanical integrity. 68.73 Section 68...) CHEMICAL ACCIDENT PREVENTION PROVISIONS Program 3 Prevention Program § 68.73 Mechanical integrity. (a... accepted good engineering practices. (3) The frequency of inspections and tests of process equipment shall...
30 CFR 250.1916 - What criteria for mechanical integrity must my SEMS program meet?
Code of Federal Regulations, 2011 CFR
2011-07-01
... 30 Mineral Resources 2 2011-07-01 2011-07-01 false What criteria for mechanical integrity must my SEMS program meet? 250.1916 Section 250.1916 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT... mechanical integrity must my SEMS program meet? You must develop and implement written procedures that...
30 CFR 250.1902 - What must I include in my SEMS program?
Code of Federal Regulations, 2011 CFR
2011-07-01
... 30 Mineral Resources 2 2011-07-01 2011-07-01 false What must I include in my SEMS program? 250.1902 Section 250.1902 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT... § 250.1915) (8) Mechanical Integrity (Assurance of Quality and Mechanical Integrity of Critical...
33 CFR 155.815 - Tank vessel integrity.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Tank vessel integrity. 155.815..., Procedures, Equipment, and Records § 155.815 Tank vessel integrity. (a) Except as provided in paragraph (b) of this section, a tank vessel underway or at anchor must have all closure mechanisms on the...
33 CFR 155.815 - Tank vessel integrity.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Tank vessel integrity. 155.815..., Procedures, Equipment, and Records § 155.815 Tank vessel integrity. (a) Except as provided in paragraph (b) of this section, a tank vessel underway or at anchor must have all closure mechanisms on the...
Semantic Congruence Accelerates the Onset of the Neural Signals of Successful Memory Encoding.
Packard, Pau A; Rodríguez-Fornells, Antoni; Bunzeck, Nico; Nicolás, Berta; de Diego-Balaguer, Ruth; Fuentemilla, Lluís
2017-01-11
As the stream of experience unfolds, our memory system rapidly transforms current inputs into long-lasting meaningful memories. A putative neural mechanism that strongly influences how input elements are transformed into meaningful memory codes relies on the ability to integrate them with existing structures of knowledge or schemas. However, it is not yet clear whether schema-related integration neural mechanisms occur during online encoding. In the current investigation, we examined the encoding-dependent nature of this phenomenon in humans. We showed that actively integrating words with congruent semantic information provided by a category cue enhances memory for words and increases false recall. The memory effect of such active integration with congruent information was robust, even with an interference task occurring right after each encoding word list. In addition, via electroencephalography, we show in 2 separate studies that the onset of the neural signals of successful encoding appeared early (∼400 ms) during the encoding of congruent words. That the neural signals of successful encoding of congruent and incongruent information followed similarly ∼200 ms later suggests that this earlier neural response contributed to memory formation. We propose that the encoding of events that are congruent with readily available contextual semantics can trigger an accelerated onset of the neural mechanisms, supporting the integration of semantic information with the event input. This faster onset would result in a long-lasting and meaningful memory trace for the event but, at the same time, make it difficult to distinguish it from plausible but never encoded events (i.e., related false memories). Conceptual or schema congruence has a strong influence on long-term memory. However, the question of whether schema-related integration neural mechanisms occur during online encoding has yet to be clarified. We investigated the neural mechanisms reflecting how the active integration of words with congruent semantic categories enhances memory for words and increases false recall of semantically related words. We analyzed event-related potentials during encoding and showed that the onset of the neural signals of successful encoding appeared early (∼400 ms) during the encoding of congruent words. Our findings indicate that congruent events can trigger an accelerated onset of neural encoding mechanisms supporting the integration of semantic information with the event input. Copyright © 2017 the authors 0270-6474/17/370291-11$15.00/0.
The levels of analysis revisited
MacDougall-Shackleton, Scott A.
2011-01-01
The term levels of analysis has been used in several ways: to distinguish between ultimate and proximate levels, to categorize different kinds of research questions and to differentiate levels of reductionism. Because questions regarding ultimate function and proximate mechanisms are logically distinct, I suggest that distinguishing between these two levels is the best use of the term. Integrating across levels in research has potential risks, but many benefits. Consideration at one level can help generate novel hypotheses at the other, define categories of behaviour and set criteria that must be addressed. Taking an adaptationist stance thus strengthens research on proximate mechanisms. Similarly, it is critical for researchers studying adaptation and function to have detailed knowledge of proximate mechanisms that may constrain or modulate evolutionary processes. Despite the benefits of integrating across ultimate and proximate levels, failure to clearly identify levels of analysis, and whether or not hypotheses are exclusive alternatives, can create false debates. Such non-alternative hypotheses may occur between or within levels, and are not limited to integrative approaches. In this review, I survey different uses of the term levels of analysis and the benefits of integration, and highlight examples of false debate within and between levels. The best integrative biology reciprocally uses ultimate and proximate hypotheses to generate a more complete understanding of behaviour. PMID:21690126
Stein, Dan J
2006-01-01
There have been significant advances in our understanding of the anxiety disorders; a range of data is now available on their epidemiology, nosology, psychobiology, and management. An integrative framework is required in order to conceptualize this data and to apply it in the clinic. This is a nonsystematic review of literature on the psychobiology of some the major anxiety disorders, focused on the idea that each of these conditions can be conceptualized in terms of a different "false alarm," mediated by specific neurocircuitry and with a particular evolutionary origin. The "false alarm" concept is able to integrate a range of data on the proximal mechanisms of anxiety disorders (including their mediating neurochemistry and neurogenetics), as well as hypotheses about the distal or evolutionary underpinnings of these conditions. Fortunately, serotonergic antidepressants and cognitive-behavioral psychotherapy appear to be able to normalize the putative "false alarms" in anxiety disorders. A better understanding of the cognitive-affective neuroscience of anxiety disorders will hopefully lead to improved treatments.
NASA Astrophysics Data System (ADS)
Cui, Yiqian; Shi, Junyou; Wang, Zili
2017-11-01
Built-in tests (BITs) are widely used in mechanical systems to perform state identification, whereas the BIT false and missed alarms cause trouble to the operators or beneficiaries to make correct judgments. Artificial neural networks (ANN) are previously used for false and missed alarms identification, which has the features such as self-organizing and self-study. However, these ANN models generally do not incorporate the temporal effect of the bottom-level threshold comparison outputs and the historical temporal features are not fully considered. To improve the situation, this paper proposes a new integrated BIT design methodology by incorporating a novel type of dynamic neural networks (DNN) model. The new DNN model is termed as Forward IIR & Recurrent FIR DNN (FIRF-DNN), where its component neurons, network structures, and input/output relationships are discussed. The condition monitoring false and missed alarms reduction implementation scheme based on FIRF-DNN model is also illustrated, which is composed of three stages including model training, false and missed alarms detection, and false and missed alarms suppression. Finally, the proposed methodology is demonstrated in the application study and the experimental results are analyzed.
Detection and identification of substances using noisy THz signal
NASA Astrophysics Data System (ADS)
Trofimov, Vyacheslav A.; Zakharova, Irina G.; Zagursky, Dmitry Yu.; Varentsova, Svetlana A.
2017-05-01
We discuss an effective method for the detection and identification of substances using a high noisy THz signal. In order to model such a noisy signal, we add to the THz signal transmitted through a pure substance, a noisy THz signal obtained in real conditions at a long distance (more than 3.5 m) from the receiver in air. The insufficiency of the standard THz-TDS method is demonstrated. The method discussed in the paper is based on time-dependent integral correlation criteria calculated using spectral dynamics of medium response. A new type of the integral correlation criterion, which is less dependent on spectral characteristics of the noisy signal under investigation, is used for the substance identification. To demonstrate the possibilities of the integral correlation criteria in real experiment, they are applied for the identification of explosive HMX in the reflection mode. To explain the physical mechanism for the false absorption frequencies appearance in the signal we make a computer simulation using 1D Maxwell's equations and density matrix formalism. We propose also new method for the substance identification by using the THz pulse frequency up-conversion and discuss an application of the cascade mechanism of molecules high energy levels excitation for the substance identification.
Huang, Yen-Tsung; Liang, Liming; Moffatt, Miriam F; Cookson, William O C M; Lin, Xihong
2015-07-01
Genome-wide association studies (GWAS) have been a standard practice in identifying single nucleotide polymorphisms (SNPs) for disease susceptibility. We propose a new approach, termed integrative GWAS (iGWAS) that exploits the information of gene expressions to investigate the mechanisms of the association of SNPs with a disease phenotype, and to incorporate the family-based design for genetic association studies. Specifically, the relations among SNPs, gene expression, and disease are modeled within the mediation analysis framework, which allows us to disentangle the genetic effect on a disease phenotype into two parts: an effect mediated through a gene expression (mediation effect, ME) and an effect through other biological mechanisms or environment-mediated mechanisms (alternative effect, AE). We develop omnibus tests for the ME and AE that are robust to underlying true disease models. Numerical studies show that the iGWAS approach is able to facilitate discovering genetic association mechanisms, and outperforms the SNP-only method for testing genetic associations. We conduct a family-based iGWAS of childhood asthma that integrates genetic and genomic data. The iGWAS approach identifies six novel susceptibility genes (MANEA, MRPL53, LYCAT, ST8SIA4, NDFIP1, and PTCH1) using the omnibus test with false discovery rate less than 1%, whereas no gene using SNP-only analyses survives with the same cut-off. The iGWAS analyses further characterize that genetic effects of these genes are mostly mediated through their gene expressions. In summary, the iGWAS approach provides a new analytic framework to investigate the mechanism of genetic etiology, and identifies novel susceptibility genes of childhood asthma that were biologically meaningful. © 2015 WILEY PERIODICALS, INC.
Trofimov, Vyacheslav A.; Varentsova, Svetlana A.; Zakharova, Irina G.; Zagursky, Dmitry Yu.
2017-01-01
Using an experiment with thin paper layers and computer simulation, we demonstrate the principal limitations of standard Time Domain Spectroscopy (TDS) based on using a broadband THz pulse for the detection and identification of a substance placed inside a disordered structure. We demonstrate the spectrum broadening of both transmitted and reflected pulses due to the cascade mechanism of the high energy level excitation considering, for example, a three-energy level medium. The pulse spectrum in the range of high frequencies remains undisturbed in the presence of a disordered structure. To avoid false absorption frequencies detection, we apply the spectral dynamics analysis method (SDA-method) together with certain integral correlation criteria (ICC). PMID:29186849
On Supporting Physical Skill Discovery
NASA Astrophysics Data System (ADS)
Furukawa, Koichi; Suwa, Masaki; Kato, Takaaki
One of the main difficulties in motor skill acquisition is attributed to body control based on wrong mental models. This is true to various domains such as playing sports and playing musical instruments. In order to acquire adequate motor skill by modifying false belief, we need to help people find appropriate key points in achieving a body control and integrate them. In this paper, we investigate three approaches to realize such support. The first one is to encourage exploration of the relations among key points constituting a motor skill, using a technique of meta-cognitive verbalization. The second one is to represent a motor skill by appropriate mechanical models. The third one is to integrate rules for component tasks in achieving a compound task. These three approaches, we argue, help people build an integrated mental model consisting of multiple relations among various key points, one that seems to be indispensable for acquisition of motor skills. These ideas suggest the possibility to create new skill rules to perform difficult tasks automatically.
Container weld identification using portable laser scanners
NASA Astrophysics Data System (ADS)
Taddei, Pierluigi; Boström, Gunnar; Puig, David; Kravtchenko, Victor; Sequeira, Vítor
2015-03-01
Identification and integrity verification of sealed containers for security applications can be obtained by employing noninvasive portable optical systems. We present a portable laser range imaging system capable of identifying welds, a byproduct of a container's physical sealing, with micrometer accuracy. It is based on the assumption that each weld has a unique three-dimensional (3-D) structure which cannot be copied or forged. We process the 3-D surface to generate a normalized depth map which is invariant to mechanical alignment errors and that is used to build compact signatures representing the weld. A weld is identified by performing cross correlations of its signature against a set of known signatures. The system has been tested on realistic datasets, containing hundreds of welds, yielding no false positives or false negatives and thus showing the robustness of the system and the validity of the chosen signature.
Integration mechanisms and hospital efficiency in integrated health care delivery systems.
Wan, Thomas T H; Lin, Blossom Yen-Ju; Ma, Allen
2002-04-01
This study analyzes integration mechanisms that affect system performances measured by indicators of efficiency in integrated delivery systems (IDSs) in the United States. The research question is, do integration mechanisms improve IDSs' efficiency in hospital care? American Hospital Association's Annual Survey (1998) and Dorenfest's Survey on Information Systems in Integrated Healthcare Delivery Systems (1998) were used to conduct the study, using IDS as the unit of analysis. A covariance structure equation model of the effects of system integration mechanisms on IDS performance was formulated and validated by an empirical examination of IDSs. The study sample includes 973 hospital-based integrated health care delivery systems operating in the United States, carried in the list of Dorenfests Survey on Information Systems in Integrated Health care Delivery Systems. The measurement indicators of system integration mechanisms are categorized into six related domains: informatic integration, case management, hybrid physician-hospital integration, forward integration, backward integration, and high tech medical services. The multivariate analysis reveals that integration mechanisms in system operation are positively correlated and positively affect IDSs' efficiency. The six domains of integration mechanisms account for 58.9% of the total variance in hospital performance. The service differentiation strategy such as having more high tech medical services have much stronger influences on efficiency than other integration mechanisms do. The beneficial effects of integration mechanisms have been realized in IDS performance. High efficiency in hospital care can be achieved by employing proper integration strategies in operations.
Taylor, Mark
2003-01-13
Tenet Healthcare Corp.'s carefully groomed reputation as a kinder and cleaner for-profit hospital chain alternative took another hit last week when the U.S. Justice Department filed a $323 million lawsuit against the company. The False Claims Act suit alleges Tenet illegally submitted thousands of false claims to maximize revenue. Lawyer Michael Ruggio says Tenet's troubles are far from over.
Flanagan, Emma C; Wong, Stephanie; Dutt, Aparna; Tu, Sicong; Bertoux, Maxime; Irish, Muireann; Piguet, Olivier; Rao, Sulakshana; Hodges, John R; Ghosh, Amitabha; Hornberger, Michael
2016-01-01
Episodic memory recall processes in Alzheimer's disease (AD) and behavioral variant frontotemporal dementia (bvFTD) can be similarly impaired, whereas recognition performance is more variable. A potential reason for this variability could be false-positive errors made on recognition trials and whether these errors are due to amnesia per se or a general over-endorsement of recognition items regardless of memory. The current study addressed this issue by analysing recognition performance on the Rey Auditory Verbal Learning Test (RAVLT) in 39 bvFTD, 77 AD and 61 control participants from two centers (India, Australia), as well as disinhibition assessed using the Hayling test. Whereas both AD and bvFTD patients were comparably impaired on delayed recall, bvFTD patients showed intact recognition performance in terms of the number of correct hits. However, both patient groups endorsed significantly more false-positives than controls, and bvFTD and AD patients scored equally poorly on a sensitivity index (correct hits-false-positives). Furthermore, measures of disinhibition were significantly associated with false positives in both groups, with a stronger relationship with false-positives in bvFTD. Voxel-based morphometry analyses revealed similar neural correlates of false positive endorsement across bvFTD and AD, with both patient groups showing involvement of prefrontal and Papez circuitry regions, such as medial temporal and thalamic regions, and a DTI analysis detected an emerging but non-significant trend between false positives and decreased fornix integrity in bvFTD only. These findings suggest that false-positive errors on recognition tests relate to similar mechanisms in bvFTD and AD, reflecting deficits in episodic memory processes and disinhibition. These findings highlight that current memory tests are not sufficient to accurately distinguish between bvFTD and AD patients.
Identifying Metabolically Active Chemicals Using a Consensus ...
Traditional toxicity testing provides insight into the mechanisms underlying toxicological responses but requires a high investment in a large number of resources. The new paradigm of testing approaches involves rapid screening studies able to evaluate thousands of chemicals across hundreds of biological targets through use of in vitro assays. Endocrine disrupting chemicals (EDCs) are of concern due to their ability to alter neurodevelopment, behavior, and reproductive success of humans and other species. A recent integrated computational model examined results across 18 ER-related assays in the ToxCast in vitro screening program to eliminate chemicals that produce a false signal by possibly interfering with the technological attributes of an individual assay. However, in vitro assays can also lead to false negatives when the complex metabolic processes that render a chemical bioactive in a living system might be unable to be replicated in an in vitro environment. In the current study, the influence of metabolism was examined for over 1,400 chemicals considered inactive using the integrated computational model. Over 2,000 first-generation and over 4,000 second-generation metabolites were generated for the inactive chemicals using in silico techniques. Next, a consensus model comprised of individual structure activity relationship (SAR) models was used to predict ER-binding activity for each of the metabolites. Binding activity was predicted for 8-10% of the meta
48 CFR 970.5232-8 - Integrated accounting.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Integrated accounting. 970... for Management and Operating Contracts 970.5232-8 Integrated accounting. As prescribed in 970.3270(b)(2), insert the following clause: Integrated Accounting (DEC 2000) Integrated accounting procedures...
Direct Instruction vs. Arts Integration: A False Dichotomy
ERIC Educational Resources Information Center
Aprill, Arnold
2010-01-01
In this article, the author takes on what he considers to be the false dichotomy between direct instruction and arts integration. He contends that at a time when national issues of sustainability and conservation of energy and resources become ever more urgent, it is time that those committed to quality arts education stop squandering time, money,…
Improving integration for integrated coastal zone management: an eight country study.
Portman, M E; Esteves, L S; Le, X Q; Khan, A Z
2012-11-15
Integrated coastal zone management (ICZM) is a widely accepted approach for sustainable management of the coastal environment. ICZM emphasizes integration across sectors, levels of government, uses, stakeholders, and spatial and temporal scales. While improving integration is central to progress in ICZM, the role of and the achievement of integration remain understudied. To further study these two points, our research analyzes the performance of specific mechanisms used to support ICZM in eight countries (Belgium, India, Israel, Italy, Portugal, Sweden, UK, and Vietnam). The assessment is based on a qualitative comparative analysis conducted through the use of two surveys. It focuses on five ICZM mechanisms (environmental impact assessment; planning hierarchy; setback lines; marine spatial planning, and regulatory commission) and their role in improving integration. Our findings indicate that certain mechanisms enhance specific types of integration more effectively than others. Environmental impact assessment enhances science-policy integration and can be useful to integrate knowledge across sectors. Planning hierarchy and regulatory commissions are effective mechanisms to integrate policies across government levels, with the latter also promoting public-government integration. Setback lines can be applied to enhance integration across landscape units. Marine spatial planning is a multi-faceted mechanism with the potential to promote all types of integration. Policy-makers should adopt the mechanisms that are suited to the type of integration needed. Results of this study also contribute to evidence-based coastal management by identifying the most common impediments related to the mechanisms of integration in the eight studied countries. Copyright © 2012 Elsevier B.V. All rights reserved.
48 CFR 1334.202 - Integrated baseline reviews.
Code of Federal Regulations, 2012 CFR
2012-10-01
... CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 1334.202 Integrated baseline reviews. An Integrated Baseline Review shall be conducted when an Earned Value Management System... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Integrated baseline...
48 CFR 1334.202 - Integrated baseline reviews.
Code of Federal Regulations, 2011 CFR
2011-10-01
... CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 1334.202 Integrated baseline reviews. An Integrated Baseline Review shall be conducted when an Earned Value Management System... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Integrated baseline...
48 CFR 1334.202 - Integrated baseline reviews.
Code of Federal Regulations, 2010 CFR
2010-10-01
... CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 1334.202 Integrated baseline reviews. An Integrated Baseline Review shall be conducted when an Earned Value Management System... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Integrated baseline...
48 CFR 1334.202 - Integrated baseline reviews.
Code of Federal Regulations, 2014 CFR
2014-10-01
... CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 1334.202 Integrated baseline reviews. An Integrated Baseline Review shall be conducted when an Earned Value Management System... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Integrated baseline...
48 CFR 1334.202 - Integrated baseline reviews.
Code of Federal Regulations, 2013 CFR
2013-10-01
... CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 1334.202 Integrated baseline reviews. An Integrated Baseline Review shall be conducted when an Earned Value Management System... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Integrated baseline...
47 CFR 64.1801 - Geographic rate averaging and rate integration.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 47 Telecommunication 3 2010-10-01 2010-10-01 false Geographic rate averaging and rate integration. 64.1801 Section 64.1801 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON... Rate Integration § 64.1801 Geographic rate averaging and rate integration. (a) The rates charged by...
48 CFR 209.571-5 - Lead system integrators.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Lead system integrators... Consultant Conflicts of Interest 209.571-5 Lead system integrators. For limitations on contractors acting as lead systems integrators, see 209.570. [75 FR 81913, Dec. 29, 2010] ...
48 CFR 209.571-5 - Lead system integrators.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Lead system integrators... Consultant Conflicts of Interest 209.571-5 Lead system integrators. For limitations on contractors acting as lead systems integrators, see 209.570. [75 FR 81913, Dec. 29, 2010] ...
48 CFR 209.571-5 - Lead system integrators.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Lead system integrators... Consultant Conflicts of Interest 209.571-5 Lead system integrators. For limitations on contractors acting as lead systems integrators, see 209.570. [75 FR 81913, Dec. 29, 2010] ...
48 CFR 209.571-5 - Lead system integrators.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Lead system integrators... Consultant Conflicts of Interest 209.571-5 Lead system integrators. For limitations on contractors acting as lead systems integrators, see 209.570. [75 FR 81913, Dec. 29, 2010] ...
46 CFR 119.435 - Integral fuel tanks.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 46 Shipping 4 2012-10-01 2012-10-01 false Integral fuel tanks. 119.435 Section 119.435 Shipping... Machinery Requirements § 119.435 Integral fuel tanks. (a) Diesel fuel tanks may not be built integral with... for certification of a vessel, integral fuel tanks must withstand a hydrostatic pressure test of 35 k...
46 CFR 119.435 - Integral fuel tanks.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 46 Shipping 4 2013-10-01 2013-10-01 false Integral fuel tanks. 119.435 Section 119.435 Shipping... Machinery Requirements § 119.435 Integral fuel tanks. (a) Diesel fuel tanks may not be built integral with... for certification of a vessel, integral fuel tanks must withstand a hydrostatic pressure test of 35 k...
Numerical analysis of biosonar beamforming mechanisms and strategies in bats.
Müller, Rolf
2010-09-01
Beamforming is critical to the function of most sonar systems. The conspicuous noseleaf and pinna shapes in bats suggest that beamforming mechanisms based on diffraction of the outgoing and incoming ultrasonic waves play a major role in bat biosonar. Numerical methods can be used to investigate the relationships between baffle geometry, acoustic mechanisms, and resulting beampatterns. Key advantages of numerical approaches are: efficient, high-resolution estimation of beampatterns, spatially dense predictions of near-field amplitudes, and the malleability of the underlying shape representations. A numerical approach that combines near-field predictions based on a finite-element formulation for harmonic solutions to the Helmholtz equation with a free-field projection based on the Kirchhoff integral to obtain estimates of the far-field beampattern is reviewed. This method has been used to predict physical beamforming mechanisms such as frequency-dependent beamforming with half-open resonance cavities in the noseleaf of horseshoe bats and beam narrowing through extension of the pinna aperture with skin folds in false vampire bats. The fine structure of biosonar beampatterns is discussed for the case of the Chinese noctule and methods for assessing the spatial information conveyed by beampatterns are demonstrated for the brown long-eared bat.
46 CFR 111.105-5 - System integrity.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 46 Shipping 4 2011-10-01 2011-10-01 false System integrity. 111.105-5 Section 111.105-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Hazardous Locations § 111.105-5 System integrity. In order to maintain system integrity, each...
46 CFR 111.105-5 - System integrity.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 46 Shipping 4 2012-10-01 2012-10-01 false System integrity. 111.105-5 Section 111.105-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Hazardous Locations § 111.105-5 System integrity. In order to maintain system integrity, each...
46 CFR 111.105-5 - System integrity.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 46 Shipping 4 2013-10-01 2013-10-01 false System integrity. 111.105-5 Section 111.105-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Hazardous Locations § 111.105-5 System integrity. In order to maintain system integrity, each...
49 CFR 244.11 - Contents of a Safety Integration Plan.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 49 Transportation 4 2014-10-01 2014-10-01 false Contents of a Safety Integration Plan. 244.11... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION REGULATIONS ON SAFETY INTEGRATION PLANS GOVERNING RAILROAD CONSOLIDATIONS, MERGERS, AND ACQUISITIONS OF CONTROL Safety Integration Plans § 244.11 Contents of a Safety...
49 CFR 244.11 - Contents of a Safety Integration Plan.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 49 Transportation 4 2013-10-01 2013-10-01 false Contents of a Safety Integration Plan. 244.11... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION REGULATIONS ON SAFETY INTEGRATION PLANS GOVERNING RAILROAD CONSOLIDATIONS, MERGERS, AND ACQUISITIONS OF CONTROL Safety Integration Plans § 244.11 Contents of a Safety...
49 CFR 244.11 - Contents of a Safety Integration Plan.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 49 Transportation 4 2011-10-01 2011-10-01 false Contents of a Safety Integration Plan. 244.11... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION REGULATIONS ON SAFETY INTEGRATION PLANS GOVERNING RAILROAD CONSOLIDATIONS, MERGERS, AND ACQUISITIONS OF CONTROL Safety Integration Plans § 244.11 Contents of a Safety...
49 CFR 244.11 - Contents of a Safety Integration Plan.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 49 Transportation 4 2012-10-01 2012-10-01 false Contents of a Safety Integration Plan. 244.11... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION REGULATIONS ON SAFETY INTEGRATION PLANS GOVERNING RAILROAD CONSOLIDATIONS, MERGERS, AND ACQUISITIONS OF CONTROL Safety Integration Plans § 244.11 Contents of a Safety...
48 CFR 552.270-27 - Integrated Agreement.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Integrated Agreement. 552... Integrated Agreement. As prescribed in 570.703, insert the following clause: Integrated Agreement (SEP 1999) This Lease, upon execution, contains the entire agreement of the parties and no prior written or oral...
45 CFR 61.14 - Confidentiality of Healthcare Integrity and Protection Data Bank information.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 45 Public Welfare 1 2012-10-01 2012-10-01 false Confidentiality of Healthcare Integrity and... GENERAL ADMINISTRATION HEALTHCARE INTEGRITY AND PROTECTION DATA BANK FOR FINAL ADVERSE INFORMATION ON HEALTH CARE PROVIDERS, SUPPLIERS AND PRACTITIONERS Disclosure of Information by the Healthcare Integrity...
45 CFR 61.14 - Confidentiality of Healthcare Integrity and Protection Data Bank information.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 45 Public Welfare 1 2010-10-01 2010-10-01 false Confidentiality of Healthcare Integrity and... GENERAL ADMINISTRATION HEALTHCARE INTEGRITY AND PROTECTION DATA BANK FOR FINAL ADVERSE INFORMATION ON HEALTH CARE PROVIDERS, SUPPLIERS AND PRACTITIONERS Disclosure of Information by the Healthcare Integrity...
45 CFR 61.14 - Confidentiality of Healthcare Integrity and Protection Data Bank information.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 45 Public Welfare 1 2011-10-01 2011-10-01 false Confidentiality of Healthcare Integrity and... GENERAL ADMINISTRATION HEALTHCARE INTEGRITY AND PROTECTION DATA BANK FOR FINAL ADVERSE INFORMATION ON HEALTH CARE PROVIDERS, SUPPLIERS AND PRACTITIONERS Disclosure of Information by the Healthcare Integrity...
49 CFR 244.11 - Contents of a Safety Integration Plan.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 49 Transportation 4 2010-10-01 2010-10-01 false Contents of a Safety Integration Plan. 244.11... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION REGULATIONS ON SAFETY INTEGRATION PLANS GOVERNING RAILROAD CONSOLIDATIONS, MERGERS, AND ACQUISITIONS OF CONTROL Safety Integration Plans § 244.11 Contents of a Safety...
40 CFR 255.31 - Integration with other acts.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Integration with other acts. 255.31 Section 255.31 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES... Relationship to Other Programs § 255.31 Integration with other acts. The Governor shall integrate the...
Sanefuji, Wakako; Haryu, Etsuko
2018-01-01
This study investigated the relationship between children’s abilities to understand causal sequences and another’s false belief. In Experiment 1, we tested 3-, 4-, 5-, and 6-year-old children (n = 28, 28, 27, and 27, respectively) using false belief and picture sequencing tasks involving mechanical, behavioral, and psychological causality. Understanding causal sequences in mechanical, behavioral, and psychological stories was related to understanding other’s false beliefs. In Experiment 2, children who failed the initial false belief task (n = 50) were reassessed 5 months later. High scorers in the sequencing of the psychological stories in Experiment 1 were more likely to pass the standard false belief task than were the low scorers. Conversely, understanding causal sequences in the mechanical and behavioral stories in Experiment 1 did not predict passing the false belief task in Experiment 2. Thus, children may understand psychological causality before they are able to use it to understand false beliefs.
49 CFR 195.452 - Pipeline integrity management in high consequence areas.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 49 Transportation 3 2013-10-01 2013-10-01 false Pipeline integrity management in high consequence... Management § 195.452 Pipeline integrity management in high consequence areas. (a) Which pipelines are covered... by this section must: (1) Develop a written integrity management program that addresses the risks on...
49 CFR 195.452 - Pipeline integrity management in high consequence areas.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 49 Transportation 3 2012-10-01 2012-10-01 false Pipeline integrity management in high consequence... Management § 195.452 Pipeline integrity management in high consequence areas. (a) Which pipelines are covered... by this section must: (1) Develop a written integrity management program that addresses the risks on...
49 CFR 195.452 - Pipeline integrity management in high consequence areas.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 49 Transportation 3 2014-10-01 2014-10-01 false Pipeline integrity management in high consequence... Management § 195.452 Pipeline integrity management in high consequence areas. (a) Which pipelines are covered... by this section must: (1) Develop a written integrity management program that addresses the risks on...
49 CFR 1106.4 - The Safety Integration Plan process.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 49 Transportation 8 2011-10-01 2011-10-01 false The Safety Integration Plan process. 1106.4... CONSIDERATION OF SAFETY INTEGRATION PLANS IN CASES INVOLVING RAILROAD CONSOLIDATIONS, MERGERS, AND ACQUISITIONS OF CONTROL § 1106.4 The Safety Integration Plan process. (a) Each applicant in a transaction subject...
49 CFR 1106.4 - The Safety Integration Plan process.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 49 Transportation 8 2013-10-01 2013-10-01 false The Safety Integration Plan process. 1106.4... CONSIDERATION OF SAFETY INTEGRATION PLANS IN CASES INVOLVING RAILROAD CONSOLIDATIONS, MERGERS, AND ACQUISITIONS OF CONTROL § 1106.4 The Safety Integration Plan process. (a) Each applicant in a transaction subject...
49 CFR 1106.4 - The Safety Integration Plan process.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 49 Transportation 8 2014-10-01 2014-10-01 false The Safety Integration Plan process. 1106.4... CONSIDERATION OF SAFETY INTEGRATION PLANS IN CASES INVOLVING RAILROAD CONSOLIDATIONS, MERGERS, AND ACQUISITIONS OF CONTROL § 1106.4 The Safety Integration Plan process. (a) Each applicant in a transaction subject...
49 CFR 1106.4 - The Safety Integration Plan process.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 49 Transportation 8 2012-10-01 2012-10-01 false The Safety Integration Plan process. 1106.4... CONSIDERATION OF SAFETY INTEGRATION PLANS IN CASES INVOLVING RAILROAD CONSOLIDATIONS, MERGERS, AND ACQUISITIONS OF CONTROL § 1106.4 The Safety Integration Plan process. (a) Each applicant in a transaction subject...
41 CFR 102-79.110 - What Integrated Workplace policy must Federal agencies strive to promote?
Code of Federal Regulations, 2012 CFR
2012-01-01
... 41 Public Contracts and Property Management 3 2012-01-01 2012-01-01 false What Integrated... Property Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT... Integrated Workplace § 102-79.110 What Integrated Workplace policy must Federal agencies strive to promote...
41 CFR 102-79.110 - What Integrated Workplace policy must Federal agencies strive to promote?
Code of Federal Regulations, 2013 CFR
2013-07-01
... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false What Integrated... Property Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT... Integrated Workplace § 102-79.110 What Integrated Workplace policy must Federal agencies strive to promote...
41 CFR 102-79.110 - What Integrated Workplace policy must Federal agencies strive to promote?
Code of Federal Regulations, 2014 CFR
2014-01-01
... 41 Public Contracts and Property Management 3 2014-01-01 2014-01-01 false What Integrated... Property Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT... Integrated Workplace § 102-79.110 What Integrated Workplace policy must Federal agencies strive to promote...
45 CFR 61.1 - The Healthcare Integrity and Protection Data Bank.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 45 Public Welfare 1 2012-10-01 2012-10-01 false The Healthcare Integrity and Protection Data Bank... HEALTHCARE INTEGRITY AND PROTECTION DATA BANK FOR FINAL ADVERSE INFORMATION ON HEALTH CARE PROVIDERS, SUPPLIERS AND PRACTITIONERS General Provisions § 61.1 The Healthcare Integrity and Protection Data Bank. (a...
45 CFR 61.1 - The Healthcare Integrity and Protection Data Bank.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 45 Public Welfare 1 2011-10-01 2011-10-01 false The Healthcare Integrity and Protection Data Bank... HEALTHCARE INTEGRITY AND PROTECTION DATA BANK FOR FINAL ADVERSE INFORMATION ON HEALTH CARE PROVIDERS, SUPPLIERS AND PRACTITIONERS General Provisions § 61.1 The Healthcare Integrity and Protection Data Bank. (a...
45 CFR 61.1 - The Healthcare Integrity and Protection Data Bank.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 45 Public Welfare 1 2010-10-01 2010-10-01 false The Healthcare Integrity and Protection Data Bank... HEALTHCARE INTEGRITY AND PROTECTION DATA BANK FOR FINAL ADVERSE INFORMATION ON HEALTH CARE PROVIDERS, SUPPLIERS AND PRACTITIONERS General Provisions § 61.1 The Healthcare Integrity and Protection Data Bank. (a...
17 CFR 230.155 - Integration of abandoned offerings.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Integration of abandoned... GENERAL RULES AND REGULATIONS, SECURITIES ACT OF 1933 General § 230.155 Integration of abandoned offerings... from integration of private and registered offerings. Because of the objectives of Rule 155 and the...
49 CFR 1106.3 - Actions for which Safety Integration Plan is required.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 49 Transportation 8 2010-10-01 2010-10-01 false Actions for which Safety Integration Plan is... TRANSPORTATION BOARD CONSIDERATION OF SAFETY INTEGRATION PLANS IN CASES INVOLVING RAILROAD CONSOLIDATIONS, MERGERS, AND ACQUISITIONS OF CONTROL § 1106.3 Actions for which Safety Integration Plan is required. A SIP...
49 CFR 1106.4 - The Safety Integration Plan process.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 49 Transportation 8 2010-10-01 2010-10-01 false The Safety Integration Plan process. 1106.4... CONSIDERATION OF SAFETY INTEGRATION PLANS IN CASES INVOLVING RAILROAD CONSOLIDATIONS, MERGERS, AND ACQUISITIONS OF CONTROL § 1106.4 The Safety Integration Plan process. (a) Each applicant in a transaction subject...
14 CFR 1214.810 - Integration of payloads.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Integration of payloads. 1214.810 Section... for Spacelab Services § 1214.810 Integration of payloads. (a) The customer shall bear the cost of... mission. (2) Generation of mission requirements and their documentation in the Payload Integration Plan...
49 CFR 192.909 - How can an operator change its integrity management program?
Code of Federal Regulations, 2011 CFR
2011-10-01
... Transmission Pipeline Integrity Management § 192.909 How can an operator change its integrity management... 49 Transportation 3 2011-10-01 2011-10-01 false How can an operator change its integrity management program? 192.909 Section 192.909 Transportation Other Regulations Relating to Transportation...
Code of Federal Regulations, 2010 CFR
2010-10-01
... 49 Transportation 4 2010-10-01 2010-10-01 false Subjects to be addressed in a Safety Integration... TRANSPORTATION REGULATIONS ON SAFETY INTEGRATION PLANS GOVERNING RAILROAD CONSOLIDATIONS, MERGERS, AND ACQUISITIONS OF CONTROL Safety Integration Plans § 244.15 Subjects to be addressed in a Safety Integration Plan...
[False recognition of faces associated with fronto-temporal dementia with prosopagnosia].
Verstichel, P
2005-09-01
The association of prosopagnosia and false recognition of faces is unusual and contributes to our understanding of the generation of facial familiarity. A 67-year-old man with a left prefrontal traumatic lesion, developed a temporal variety of fronto-temporal dementia (semantic dementia) with amyotrophic lateral sclerosis. Cerebral imagery demonstrated a bilateral, temporal anterior atrophy predominating in the right hemisphere. The main cognitive signs consisted in severe difficulties to recognize faces of familiar people (prosopagnosia), associated with systematic false recognition of unfamiliar people. Neuropsychological testing indicated that the prosopagnosia probably resulted from the association of an associative/mnemonic mechanism (inability to activate the Face Recognition Units (FRU) from the visual input) and a semantic mechanism (degradation of semantic/biographical information or deconnexion between FRU and this information). At the early stage of the disease, the patient could activate residual semantic information about individuals from their names, but after a 4-year course, he failed to do so. This worsening could be attributed to the extension of the degenerative lesions to the left temporal lobe. Familiar and unfamiliar faces triggered a marked feeling of knowing. False recognition concerned all the unfamiliar faces, and the patient claimed spontaneously that they corresponded to actors, but he could not provide any additional information about their specific identities. The coexistence of prosopagnosia and false recognition suggests the existence of different interconnected systems processing face recognition, one intended to identification of individuals, and the other producing the sense of familiarity. Dysfunctions at different stages of one or the other of these two processes could result in distortions in the feeling of knowing. From this case and others reported in literature, we propose to complete the classical model of face processing by adding a pathway linked to limbic system and frontal structures. This later pathway could normally emit signals for familiarity, essentially autonomic, in response to the familiar faces. These signals, primitively unconscious, secondly reach consciousness and are then integrated by a central supervisor system which evaluates and verifies identity-specific biographical information in order to make a decision about the sense of familiarity.
48 CFR 3009.570 - Limitations on contractors acting as lead system integrators.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 48 Federal Acquisition Regulations System 7 2011-10-01 2011-10-01 false Limitations on contractors acting as lead system integrators. 3009.570 Section 3009.570 Federal Acquisition Regulations System... contractors acting as lead system integrators. ...
48 CFR 34.202 - Integrated Baseline Reviews.
Code of Federal Regulations, 2011 CFR
2011-10-01
... inherent risks in offerors'/contractors' performance plans and the underlying management control systems...) The degree to which the management process provides effective and integrated technical/schedule/cost... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Integrated Baseline...
48 CFR 1034.202 - Integrated Baseline Reviews.
Code of Federal Regulations, 2011 CFR
2011-10-01
... which the management process provides effective and integrated technical/schedule/cost planning and... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Integrated Baseline... SPECIAL CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 1034.202...
46 CFR 182.435 - Integral fuel tanks.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 46 Shipping 7 2011-10-01 2011-10-01 false Integral fuel tanks. 182.435 Section 182.435 Shipping...) MACHINERY INSTALLATION Specific Machinery Requirements § 182.435 Integral fuel tanks. (a) Gasoline fuel tanks must be independent of the hull. (b) Diesel fuel tanks may not be built integral with the hull of...
46 CFR 182.435 - Integral fuel tanks.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 46 Shipping 7 2012-10-01 2012-10-01 false Integral fuel tanks. 182.435 Section 182.435 Shipping...) MACHINERY INSTALLATION Specific Machinery Requirements § 182.435 Integral fuel tanks. (a) Gasoline fuel tanks must be independent of the hull. (b) Diesel fuel tanks may not be built integral with the hull of...
46 CFR 182.435 - Integral fuel tanks.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 46 Shipping 7 2010-10-01 2010-10-01 false Integral fuel tanks. 182.435 Section 182.435 Shipping...) MACHINERY INSTALLATION Specific Machinery Requirements § 182.435 Integral fuel tanks. (a) Gasoline fuel tanks must be independent of the hull. (b) Diesel fuel tanks may not be built integral with the hull of...
46 CFR 182.435 - Integral fuel tanks.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 46 Shipping 7 2013-10-01 2013-10-01 false Integral fuel tanks. 182.435 Section 182.435 Shipping...) MACHINERY INSTALLATION Specific Machinery Requirements § 182.435 Integral fuel tanks. (a) Gasoline fuel tanks must be independent of the hull. (b) Diesel fuel tanks may not be built integral with the hull of...
46 CFR 169.234 - Integral fuel oil tank examinations.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 46 Shipping 7 2012-10-01 2012-10-01 false Integral fuel oil tank examinations. 169.234 Section 169... VESSELS Inspection and Certification Drydocking Or Hauling Out § 169.234 Integral fuel oil tank examinations. (a) Each fuel oil tank with at least one side integral to the vessel's hull and located within...
46 CFR 169.234 - Integral fuel oil tank examinations.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 46 Shipping 7 2013-10-01 2013-10-01 false Integral fuel oil tank examinations. 169.234 Section 169... VESSELS Inspection and Certification Drydocking Or Hauling Out § 169.234 Integral fuel oil tank examinations. (a) Each fuel oil tank with at least one side integral to the vessel's hull and located within...
46 CFR 169.234 - Integral fuel oil tank examinations.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 46 Shipping 7 2011-10-01 2011-10-01 false Integral fuel oil tank examinations. 169.234 Section 169... VESSELS Inspection and Certification Drydocking Or Hauling Out § 169.234 Integral fuel oil tank examinations. (a) Each fuel oil tank with at least one side integral to the vessel's hull and located within...
46 CFR 169.234 - Integral fuel oil tank examinations.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 46 Shipping 7 2014-10-01 2014-10-01 false Integral fuel oil tank examinations. 169.234 Section 169... VESSELS Inspection and Certification Drydocking Or Hauling Out § 169.234 Integral fuel oil tank examinations. (a) Each fuel oil tank with at least one side integral to the vessel's hull and located within...
26 CFR 1.1275-6 - Integration of qualifying debt instruments.
Code of Federal Regulations, 2012 CFR
2012-04-01
... 26 Internal Revenue 11 2012-04-01 2012-04-01 false Integration of qualifying debt instruments. 1... Losses § 1.1275-6 Integration of qualifying debt instruments. (a) In general. This section generally provides for the integration of a qualifying debt instrument with a hedge or combination of hedges if the...
26 CFR 1.1275-6 - Integration of qualifying debt instruments.
Code of Federal Regulations, 2013 CFR
2013-04-01
... 26 Internal Revenue 11 2013-04-01 2013-04-01 false Integration of qualifying debt instruments. 1... Losses § 1.1275-6 Integration of qualifying debt instruments. (a) In general. This section generally provides for the integration of a qualifying debt instrument with a hedge or combination of hedges if the...
26 CFR 1.1275-6 - Integration of qualifying debt instruments.
Code of Federal Regulations, 2014 CFR
2014-04-01
... 26 Internal Revenue 11 2014-04-01 2014-04-01 false Integration of qualifying debt instruments. 1... Losses § 1.1275-6 Integration of qualifying debt instruments. (a) In general. This section generally provides for the integration of a qualifying debt instrument with a hedge or combination of hedges if the...
26 CFR 1.1275-6 - Integration of qualifying debt instruments.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 26 Internal Revenue 11 2011-04-01 2011-04-01 false Integration of qualifying debt instruments. 1... Losses § 1.1275-6 Integration of qualifying debt instruments. (a) In general. This section generally provides for the integration of a qualifying debt instrument with a hedge or combination of hedges if the...
49 CFR 192.911 - What are the elements of an integrity management program?
Code of Federal Regulations, 2012 CFR
2012-10-01
...? An operator's initial integrity management program begins with a framework (see § 192.907) and...), by electronic or other means, a copy of the operator's risk analysis or integrity management program... 49 Transportation 3 2012-10-01 2012-10-01 false What are the elements of an integrity management...
49 CFR 192.911 - What are the elements of an integrity management program?
Code of Federal Regulations, 2014 CFR
2014-10-01
...? An operator's initial integrity management program begins with a framework (see § 192.907) and...), by electronic or other means, a copy of the operator's risk analysis or integrity management program... 49 Transportation 3 2014-10-01 2014-10-01 false What are the elements of an integrity management...
49 CFR 192.911 - What are the elements of an integrity management program?
Code of Federal Regulations, 2013 CFR
2013-10-01
...? An operator's initial integrity management program begins with a framework (see § 192.907) and...), by electronic or other means, a copy of the operator's risk analysis or integrity management program... 49 Transportation 3 2013-10-01 2013-10-01 false What are the elements of an integrity management...
49 CFR 192.911 - What are the elements of an integrity management program?
Code of Federal Regulations, 2011 CFR
2011-10-01
...? An operator's initial integrity management program begins with a framework (see § 192.907) and...), by electronic or other means, a copy of the operator's risk analysis or integrity management program... 49 Transportation 3 2011-10-01 2011-10-01 false What are the elements of an integrity management...
Theory of mind in schizophrenia: exploring neural mechanisms of belief attribution.
Lee, Junghee; Quintana, Javier; Nori, Poorang; Green, Michael F
2011-01-01
Although previous behavioral studies have shown that schizophrenia patients have impaired theory of mind (ToM), the neural mechanisms associated with this impairment are poorly understood. This study aimed to identify the neural mechanisms of ToM in schizophrenia, using functional magnetic resonance imaging (fMRI) with a belief attribution task. In the scanner, 12 schizophrenia patients and 13 healthy control subjects performed the belief attribution task with three conditions: a false belief condition, a false photograph condition, and a simple reading condition. For the false belief versus simple reading conditions, schizophrenia patients showed reduced neural activation in areas including the temporoparietal junction (TPJ) and medial prefrontal cortex (MPFC) compared with controls. Further, during the false belief versus false photograph conditions, we observed increased activations in the TPJ and the MPFC in healthy controls, but not in schizophrenia patients. For the false photograph versus simple reading condition, both groups showed comparable neural activations. Schizophrenia patients showed reduced task-related activation in the TPJ and the MPFC during the false belief condition compared with controls, but not for the false photograph condition. This pattern suggests that reduced activation in these regions is associated with, and specific to, impaired ToM in schizophrenia.
MOST: most-similar ligand based approach to target prediction.
Huang, Tao; Mi, Hong; Lin, Cheng-Yuan; Zhao, Ling; Zhong, Linda L D; Liu, Feng-Bin; Zhang, Ge; Lu, Ai-Ping; Bian, Zhao-Xiang
2017-03-11
Many computational approaches have been used for target prediction, including machine learning, reverse docking, bioactivity spectra analysis, and chemical similarity searching. Recent studies have suggested that chemical similarity searching may be driven by the most-similar ligand. However, the extent of bioactivity of most-similar ligands has been oversimplified or even neglected in these studies, and this has impaired the prediction power. Here we propose the MOst-Similar ligand-based Target inference approach, namely MOST, which uses fingerprint similarity and explicit bioactivity of the most-similar ligands to predict targets of the query compound. Performance of MOST was evaluated by using combinations of different fingerprint schemes, machine learning methods, and bioactivity representations. In sevenfold cross-validation with a benchmark Ki dataset from CHEMBL release 19 containing 61,937 bioactivity data of 173 human targets, MOST achieved high average prediction accuracy (0.95 for pKi ≥ 5, and 0.87 for pKi ≥ 6). Morgan fingerprint was shown to be slightly better than FP2. Logistic Regression and Random Forest methods performed better than Naïve Bayes. In a temporal validation, the Ki dataset from CHEMBL19 were used to train models and predict the bioactivity of newly deposited ligands in CHEMBL20. MOST also performed well with high accuracy (0.90 for pKi ≥ 5, and 0.76 for pKi ≥ 6), when Logistic Regression and Morgan fingerprint were employed. Furthermore, the p values associated with explicit bioactivity were found be a robust index for removing false positive predictions. Implicit bioactivity did not offer this capability. Finally, p values generated with Logistic Regression, Morgan fingerprint and explicit activity were integrated with a false discovery rate (FDR) control procedure to reduce false positives in multiple-target prediction scenario, and the success of this strategy it was demonstrated with a case of fluanisone. In the case of aloe-emodin's laxative effect, MOST predicted that acetylcholinesterase was the mechanism-of-action target; in vivo studies validated this prediction. Using the MOST approach can result in highly accurate and robust target prediction. Integrated with a FDR control procedure, MOST provides a reliable framework for multiple-target inference. It has prospective applications in drug repurposing and mechanism-of-action target prediction.
42 CFR 455.232 - Medicaid integrity audit program contractor functions.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 42 Public Health 4 2012-10-01 2012-10-01 false Medicaid integrity audit program contractor functions. 455.232 Section 455.232 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS PROGRAM INTEGRITY: MEDICAID Medicaid...
42 CFR 455.232 - Medicaid integrity audit program contractor functions.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 42 Public Health 4 2014-10-01 2014-10-01 false Medicaid integrity audit program contractor functions. 455.232 Section 455.232 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS PROGRAM INTEGRITY: MEDICAID Medicaid...
42 CFR 455.232 - Medicaid integrity audit program contractor functions.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 42 Public Health 4 2011-10-01 2011-10-01 false Medicaid integrity audit program contractor functions. 455.232 Section 455.232 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS PROGRAM INTEGRITY: MEDICAID Medicaid...
42 CFR 455.232 - Medicaid integrity audit program contractor functions.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 42 Public Health 4 2010-10-01 2010-10-01 false Medicaid integrity audit program contractor functions. 455.232 Section 455.232 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS PROGRAM INTEGRITY: MEDICAID Medicaid...
14 CFR 313.7 - Integration with environmental procedures.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 14 Aeronautics and Space 4 2011-01-01 2011-01-01 false Integration with environmental procedures....7 Integration with environmental procedures. (a) In proceedings in which an environmental impact... information. However, it shall remain the responsibility of the administrative law judge or the DOT...
14 CFR 313.7 - Integration with environmental procedures.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 14 Aeronautics and Space 4 2014-01-01 2014-01-01 false Integration with environmental procedures....7 Integration with environmental procedures. (a) In proceedings in which an environmental impact... information. However, it shall remain the responsibility of the administrative law judge or the DOT...
14 CFR 313.7 - Integration with environmental procedures.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 14 Aeronautics and Space 4 2012-01-01 2012-01-01 false Integration with environmental procedures....7 Integration with environmental procedures. (a) In proceedings in which an environmental impact... information. However, it shall remain the responsibility of the administrative law judge or the DOT...
14 CFR 313.7 - Integration with environmental procedures.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 14 Aeronautics and Space 4 2013-01-01 2013-01-01 false Integration with environmental procedures....7 Integration with environmental procedures. (a) In proceedings in which an environmental impact... information. However, it shall remain the responsibility of the administrative law judge or the DOT...
48 CFR 970.5232-8 - Integrated accounting.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Integrated accounting. 970... for Management and Operating Contracts 970.5232-8 Integrated accounting. As prescribed in 970.3270(b... are required for use under this contract. The Contractor's financial management system shall include...
48 CFR 970.5232-8 - Integrated accounting.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Integrated accounting. 970... for Management and Operating Contracts 970.5232-8 Integrated accounting. As prescribed in 970.3270(b... are required for use under this contract. The Contractor's financial management system shall include...
48 CFR 970.5232-8 - Integrated accounting.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Integrated accounting. 970... for Management and Operating Contracts 970.5232-8 Integrated accounting. As prescribed in 970.3270(b... are required for use under this contract. The Contractor's financial management system shall include...
48 CFR 970.5232-8 - Integrated accounting.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Integrated accounting. 970... for Management and Operating Contracts 970.5232-8 Integrated accounting. As prescribed in 970.3270(b... are required for use under this contract. The Contractor's financial management system shall include...
14 CFR 313.7 - Integration with environmental procedures.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Integration with environmental procedures. 313.7 Section 313.7 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION....7 Integration with environmental procedures. (a) In proceedings in which an environmental impact...
46 CFR 111.50-2 - Systems integration.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 46 Shipping 4 2010-10-01 2010-10-01 false Systems integration. 111.50-2 Section 111.50-2 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Overcurrent Protection § 111.50-2 Systems integration. The electrical characteristics of each...
42 CFR 493.1232 - Standard: Specimen identification and integrity.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 42 Public Health 5 2010-10-01 2010-10-01 false Standard: Specimen identification and integrity... Nonwaived Testing General Laboratory Systems § 493.1232 Standard: Specimen identification and integrity. The laboratory must establish and follow written policies and procedures that ensure positive identification and...
Code of Federal Regulations, 2013 CFR
2013-10-01
...: MINIMUM FEDERAL SAFETY STANDARDS Gas Transmission Pipeline Integrity Management § 192.915 What knowledge... to the integrity management program possesses and maintains a thorough knowledge of the integrity... 49 Transportation 3 2013-10-01 2013-10-01 false What knowledge and training must personnel have to...
Code of Federal Regulations, 2014 CFR
2014-10-01
...: MINIMUM FEDERAL SAFETY STANDARDS Gas Transmission Pipeline Integrity Management § 192.915 What knowledge... to the integrity management program possesses and maintains a thorough knowledge of the integrity... 49 Transportation 3 2014-10-01 2014-10-01 false What knowledge and training must personnel have to...
Code of Federal Regulations, 2011 CFR
2011-10-01
...: MINIMUM FEDERAL SAFETY STANDARDS Gas Transmission Pipeline Integrity Management § 192.915 What knowledge... to the integrity management program possesses and maintains a thorough knowledge of the integrity... 49 Transportation 3 2011-10-01 2011-10-01 false What knowledge and training must personnel have to...
Code of Federal Regulations, 2012 CFR
2012-10-01
...: MINIMUM FEDERAL SAFETY STANDARDS Gas Transmission Pipeline Integrity Management § 192.915 What knowledge... to the integrity management program possesses and maintains a thorough knowledge of the integrity... 49 Transportation 3 2012-10-01 2012-10-01 false What knowledge and training must personnel have to...
48 CFR 970.5223-1 - Integration of environment, safety, and health into work planning and execution.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Integration of environment... Integration of environment, safety, and health into work planning and execution. As prescribed in 970.2303-3(b), insert the following clause: Integration of Environment, Safety, and Health Into Work Planning and...
Code of Federal Regulations, 2010 CFR
2010-07-01
... 34 Education 3 2010-07-01 2010-07-01 false What is the Demonstration Projects for the Integration... EDUCATION DEMONSTRATION PROJECTS FOR THE INTEGRATION OF VOCATIONAL AND ACADEMIC LEARNING PROGRAM General § 425.1 What is the Demonstration Projects for the Integration of Vocational and Academic Learning...
METHODS FOR DETERMINING THE MECHANICAL INTEGRITY OF CLASS II INJECTION WELLS
The mechanical integrity of injection wells must be determined to insure that there is no significant leak in the casing, tubing or packer, and that there is no significant fluid movement through vertical channels adjacent to the injection well. Methods for mechanical integrity t...
Li, Shuxia; Zhu, Dongyi; Duan, Hongmei; Ren, Anran; Glintborg, Dorte; Andersen, Marianne; Skov, Vibe; Thomassen, Mads; Kruse, Torben; Tan, Qihua
2017-03-28
As a universally common endocrinopathy in women of reproductive age, the polycystic ovarian syndrome is characterized by composite clinical phenotypes reflecting the contributions of reproductive impact of ovarian dysfunction and metabolic abnormalities with widely varying symptoms resulting from interference of the genome with the environment through integrative biological mechanisms including epigenetics. We have performed a genome-wide DNA methylation analysis on polycystic ovarian syndrome and identified a substantial number of genomic sites differentially methylated in the whole blood of PCOS patients and healthy controls (52 sites, false discovery rate < 0.05 and corresponding p value < 5.68e-06), highly consistently replicating biological pathways extensively implicated in immunity and immunity-related inflammatory disorders (false discovery rate < 0.05) that were reportedly regulated in the DNA methylome from ovarian tissue under PCOS condition. Most importantly, our genome-wide profiling focusing on PCOS patients revealed a large number of DNA methylation sites and their enriched functional pathways significantly associated with diverse clinical features (levels of prolactin, estradiol, progesterone and menstrual cycle) that could serve as novel molecular basis of the clinical heterogeneity observed in PCOS women.
46 CFR 109.209 - Appliances for watertight integrity.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 46 Shipping 4 2013-10-01 2013-10-01 false Appliances for watertight integrity. 109.209 Section 109.209 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS OPERATIONS Tests, Drills, and Inspections § 109.209 Appliances for watertight integrity. (a) Before getting...
46 CFR 109.209 - Appliances for watertight integrity.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 46 Shipping 4 2010-10-01 2010-10-01 false Appliances for watertight integrity. 109.209 Section 109.209 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS OPERATIONS Tests, Drills, and Inspections § 109.209 Appliances for watertight integrity. (a) Before getting...
46 CFR 109.209 - Appliances for watertight integrity.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 46 Shipping 4 2012-10-01 2012-10-01 false Appliances for watertight integrity. 109.209 Section 109.209 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS OPERATIONS Tests, Drills, and Inspections § 109.209 Appliances for watertight integrity. (a) Before getting...
46 CFR 109.209 - Appliances for watertight integrity.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 46 Shipping 4 2011-10-01 2011-10-01 false Appliances for watertight integrity. 109.209 Section 109.209 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS OPERATIONS Tests, Drills, and Inspections § 109.209 Appliances for watertight integrity. (a) Before getting...
46 CFR 109.209 - Appliances for watertight integrity.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 46 Shipping 4 2014-10-01 2014-10-01 false Appliances for watertight integrity. 109.209 Section 109.209 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS OPERATIONS Tests, Drills, and Inspections § 109.209 Appliances for watertight integrity. (a) Before getting...
46 CFR 108.665 - Appliances for watertight integrity.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 46 Shipping 4 2010-10-01 2010-10-01 false Appliances for watertight integrity. 108.665 Section 108.665 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Equipment Markings and Instructions § 108.665 Appliances for watertight integrity...
48 CFR 208.7003-1 - Assignments under integrated materiel management (IMM).
Code of Federal Regulations, 2014 CFR
2014-10-01
... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Assignments under integrated materiel management (IMM). 208.7003-1 Section 208.7003-1 Federal Acquisition Regulations System... SUPPLIES AND SERVICES Coordinated Acquisition 208.7003-1 Assignments under integrated materiel management...
48 CFR 208.7003-1 - Assignments under integrated materiel management (IMM).
Code of Federal Regulations, 2011 CFR
2011-10-01
... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Assignments under integrated materiel management (IMM). 208.7003-1 Section 208.7003-1 Federal Acquisition Regulations System... SUPPLIES AND SERVICES Coordinated Acquisition 208.7003-1 Assignments under integrated materiel management...
48 CFR 208.7003-1 - Assignments under integrated materiel management (IMM).
Code of Federal Regulations, 2012 CFR
2012-10-01
... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Assignments under integrated materiel management (IMM). 208.7003-1 Section 208.7003-1 Federal Acquisition Regulations System... SUPPLIES AND SERVICES Coordinated Acquisition 208.7003-1 Assignments under integrated materiel management...
48 CFR 208.7003-1 - Assignments under integrated materiel management (IMM).
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Assignments under integrated materiel management (IMM). 208.7003-1 Section 208.7003-1 Federal Acquisition Regulations System... SUPPLIES AND SERVICES Coordinated Acquisition 208.7003-1 Assignments under integrated materiel management...
48 CFR 208.7003-1 - Assignments under integrated materiel management (IMM).
Code of Federal Regulations, 2013 CFR
2013-10-01
... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Assignments under integrated materiel management (IMM). 208.7003-1 Section 208.7003-1 Federal Acquisition Regulations System... SUPPLIES AND SERVICES Coordinated Acquisition 208.7003-1 Assignments under integrated materiel management...
Medical Image Tamper Detection Based on Passive Image Authentication.
Ulutas, Guzin; Ustubioglu, Arda; Ustubioglu, Beste; V Nabiyev, Vasif; Ulutas, Mustafa
2017-12-01
Telemedicine has gained popularity in recent years. Medical images can be transferred over the Internet to enable the telediagnosis between medical staffs and to make the patient's history accessible to medical staff from anywhere. Therefore, integrity protection of the medical image is a serious concern due to the broadcast nature of the Internet. Some watermarking techniques are proposed to control the integrity of medical images. However, they require embedding of extra information (watermark) into image before transmission. It decreases visual quality of the medical image and can cause false diagnosis. The proposed method uses passive image authentication mechanism to detect the tampered regions on medical images. Structural texture information is obtained from the medical image by using local binary pattern rotation invariant (LBPROT) to make the keypoint extraction techniques more successful. Keypoints on the texture image are obtained with scale invariant feature transform (SIFT). Tampered regions are detected by the method by matching the keypoints. The method improves the keypoint-based passive image authentication mechanism (they do not detect tampering when the smooth region is used for covering an object) by using LBPROT before keypoint extraction because smooth regions also have texture information. Experimental results show that the method detects tampered regions on the medical images even if the forged image has undergone some attacks (Gaussian blurring/additive white Gaussian noise) or the forged regions are scaled/rotated before pasting.
A framework for understanding outcomes of integrated care programs for the hospitalised elderly
Hartgerink, Jacqueline M.; Cramm, Jane M.; van Wijngaarden, Jeroen D.H.; Bakker, Ton J.E.M.; Mackenbach, Johan P.; Nieboer, Anna P.
2013-01-01
Introduction Integrated care has emerged as a new strategy to enhance the quality of care for hospitalised elderly. Current models do not provide insight into the mechanisms underlying integrated care delivery. Therefore, we developed a framework to identify the underlying mechanisms of integrated care delivery. We should understand how they operate and interact, so that integrated care programmes can enhance the quality of care and eventually patient outcomes. Theory and methods Interprofessional collaboration among professionals is considered to be critical in integrated care delivery due to many interdependent work requirements. A review of integrated care components brings to light a distinction between the cognitive and behavioural components of interprofessional collaboration. Results Effective integrated care programmes combine the interacting components of care delivery. These components affect professionals’ cognitions and behaviour, which in turn affect quality of care. Insight is gained into how these components alter the way care is delivered through mechanisms such as combining individual knowledge and actively seeking new information. Conclusion We expect that insight into the cognitive and behavioural mechanisms will contribute to the understanding of integrated care programmes. The framework can be used to identify the underlying mechanisms of integrated care responsible for producing favourable outcomes, allowing comparisons across programmes. PMID:24363635
12 CFR 1281.23 - Bank data integrity.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 12 Banks and Banking 7 2011-01-01 2011-01-01 false Bank data integrity. 1281.23 Section 1281.23 Banks and Banking FEDERAL HOUSING FINANCE AGENCY HOUSING GOALS AND MISSION FEDERAL HOME LOAN BANK HOUSING GOALS Reporting Requirements § 1281.23 Bank data integrity. (a) Certification. (1) The senior...
19 CFR 10.532 - Integrated Sourcing Initiative.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 19 Customs Duties 1 2010-04-01 2010-04-01 false Integrated Sourcing Initiative. 10.532 Section 10... Trade Agreement Rules of Origin § 10.532 Integrated Sourcing Initiative. (a) For purposes of General... Sourcing Initiative if: (1) The good, in its condition as imported, is both classified in a tariff...
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Densitometer/scanner (integrating, reflectance, TLC, or radiochromatogram) for clinical use. 862.2400 Section 862.2400 Food and Drugs FOOD AND DRUG... CLINICAL TOXICOLOGY DEVICES Clinical Laboratory Instruments § 862.2400 Densitometer/scanner (integrating...
48 CFR 3007.106-70 - Limitations on Lead System Integrators.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 48 Federal Acquisition Regulations System 7 2012-10-01 2012-10-01 false Limitations on Lead System... Acquisition Plans 3007.106-70 Limitations on Lead System Integrators. See (HSAR) 48 CFR 3009.570 for policy applicable to acquisition strategies that consider the use of lead system integrators. ...
48 CFR 3007.106-70 - Limitations on Lead System Integrators.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 48 Federal Acquisition Regulations System 7 2014-10-01 2014-10-01 false Limitations on Lead System... Acquisition Plans 3007.106-70 Limitations on Lead System Integrators. See (HSAR) 48 CFR 3009.570 for policy applicable to acquisition strategies that consider the use of lead system integrators. ...
48 CFR 3007.106-70 - Limitations on Lead System Integrators.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 48 Federal Acquisition Regulations System 7 2011-10-01 2011-10-01 false Limitations on Lead System... Acquisition Plans 3007.106-70 Limitations on Lead System Integrators. See (HSAR) 48 CFR 3009.570 for policy applicable to acquisition strategies that consider the use of lead system integrators. ...
48 CFR 3007.106-70 - Limitations on Lead System Integrators.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Limitations on Lead System... Acquisition Plans 3007.106-70 Limitations on Lead System Integrators. See (HSAR) 48 CFR 3009.570 for policy applicable to acquisition strategies that consider the use of lead system integrators. ...
Theory of mind in schizophrenia: Exploring neural mechanisms of belief attribution
Lee, Junghee; Quintana, Javier; Nori, Poorang; Green, Michael F.
2014-01-01
Background Although previous behavioral studies have shown that schizophrenia patients have impaired theory of mind (ToM), the neural mechanisms associated with this impairment are poorly understood. This study aimed to identify the neural mechanisms of ToM in schizophrenia using functional magnetic resonance imaging (fMRI) with a Belief Attribution Task. Methods In the scanner, 12 schizophrenia patients and 13 healthy control subjects performed the Belief Attribution Task with 3 conditions: a false belief condition, a false photograph condition, and a simple reading condition. Results For the false belief vs. simple reading conditions, schizophrenia patients showed reduced neural activation in areas including the temporo-parietal junction (TPJ) and medial prefrontal cortex (MPFC) compared with controls. Further, during the false belief vs. false photograph conditions we observed increased activations in the TPJ and the MPFC in healthy controls, but not in schizophrenia patients. For the false photograph vs. simple reading condition, both groups showed comparable neural activations. Conclusions Schizophrenia patients showed reduced task-related activation in the TPJ and the MPFC during the false belief condition compared with controls, but not for the false photograph condition. This pattern suggests that reduced activation in these regions is associated with, and specific to, impaired ToM in schizophrenia. PMID:22050432
Code of Federal Regulations, 2012 CFR
2012-01-01
... 10 Energy 4 2012-01-01 2012-01-01 false Who must comply with the integrated resource planning and reporting regulations in this subpart? 905.10 Section 905.10 Energy DEPARTMENT OF ENERGY ENERGY PLANNING AND MANAGEMENT PROGRAM Integrated Resource Planning § 905.10 Who must comply with the integrated resource...
Code of Federal Regulations, 2011 CFR
2011-01-01
... 10 Energy 4 2011-01-01 2011-01-01 false Who must comply with the integrated resource planning and reporting regulations in this subpart? 905.10 Section 905.10 Energy DEPARTMENT OF ENERGY ENERGY PLANNING AND MANAGEMENT PROGRAM Integrated Resource Planning § 905.10 Who must comply with the integrated resource...
Díez, Emiliano; Gómez-Ariza, Carlos J; Díez-Álamo, Antonio M; Alonso, María A; Fernandez, Angel
2017-08-01
A dominant view of the role of the anterior temporal lobe (ATL) in semantic memory is that it serves as an integration hub, specialized in the processing of semantic relatedness by way of mechanisms that bind together information from different brain areas to form coherent amodal representations of concepts. Two recent experiments, using brain stimulation techniques along with the Deese-Roediger-McDermott (DRM) paradigm, have found a consistent false memory reduction effect following stimulation of the ATL, pointing to the importance of the ATL in semantic/conceptual processing. To more precisely identify the specific process being involved, we conducted a DRM experiment in which transcranial direct current stimulation (anode/cathode/sham) was applied over the participants' left ATL during the study of lists of words that were associatively related to their non-presented critical words (e.g., rotten, worm, red, tree, liqueur, unripe, cake, food, eden, peel, for the critical item apple) or categorically related (e.g., pear, banana, peach, orange, cantaloupe, watermelon, strawberry, cherry, kiwi, plum, for the same critical item apple). The results showed that correct recognition was not affected by stimulation. However, an interaction between stimulation condition and type of relation for false memories was found, explained by a significant false recognition reduction effect in the anodal condition for associative lists that was not observed for categorical lists. Results are congruent with previous findings and, more importantly, they help to clarify the nature and locus of false memory reduction effects, suggesting a differential role of the left ATL, and providing critical evidence for understanding the creation of semantic relatedness-based memory illusions. Copyright © 2017 Elsevier Ltd. All rights reserved.
Okandan, Murat; Nielson, Gregory N
2014-12-09
Accessing a workpiece object in semiconductor processing is disclosed. The workpiece object includes a mechanical support substrate, a release layer over the mechanical support substrate, and an integrated circuit substrate coupled over the release layer. The integrated circuit substrate includes a device layer having semiconductor devices. The method also includes etching through-substrate via (TSV) openings through the integrated circuit substrate that have buried ends at or within the release layer including using the release layer as an etch stop. TSVs are formed by introducing one or more conductive materials into the TSV openings. A die singulation trench is etched at least substantially through the integrated circuit substrate around a perimeter of an integrated circuit die. The integrated circuit die is at least substantially released from the mechanical support substrate.
ERIC Educational Resources Information Center
Naito, Mika; Seki, Yoshimi
2009-01-01
To investigate the relation between cognitive and affective social understanding, Japanese 4- to 8-year-olds received tasks of first- and second-order false beliefs and prosocial and self-presentational display rules. From 6 to 8 years, children comprehended display rules, as well as second-order false belief, using social pressures justifications…
37 CFR 10.22 - Maintaining integrity and competence of the legal profession.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Maintaining integrity and competence of the legal profession. 10.22 Section 10.22 Patents, Trademarks, and Copyrights UNITED STATES... integrity and competence of the legal profession. (a) A practitioner is subject to discipline if the...
Code of Federal Regulations, 2010 CFR
2010-07-01
... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Where may Executive agencies find additional information on Integrated Workplace concepts? 102-79.111 Section 102-79.111 Public... Integrated Workplace concepts? The GSA Office of Governmentwide Policy provides additional guidance in its...
28 CFR 25.5 - Validation and data integrity of records in the system.
Code of Federal Regulations, 2010 CFR
2010-07-01
... INFORMATION SYSTEMS The National Instant Criminal Background Check System § 25.5 Validation and data integrity... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Validation and data integrity of records... verify that the information provided to the NICS Index remains valid and correct. (b) Each data source...
33 CFR 230.20 - Integration with State and local procedures.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Integration with State and local procedures. 230.20 Section 230.20 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE PROCEDURES FOR IMPLEMENTING NEPA § 230.20 Integration with State and local procedures...
7 CFR 4290.1940 - Integration of this part with other regulations applicable to USDA's programs.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 7 Agriculture 15 2010-01-01 2010-01-01 false Integration of this part with other regulations applicable to USDA's programs. 4290.1940 Section 4290.1940 Agriculture Regulations of the Department of... AGRICULTURE RURAL BUSINESS INVESTMENT COMPANY (âRBICâ) PROGRAM Miscellaneous § 4290.1940 Integration of this...
28 CFR 25.5 - Validation and data integrity of records in the system.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 28 Judicial Administration 1 2011-07-01 2011-07-01 false Validation and data integrity of records in the system. 25.5 Section 25.5 Judicial Administration DEPARTMENT OF JUSTICE DEPARTMENT OF JUSTICE INFORMATION SYSTEMS The National Instant Criminal Background Check System § 25.5 Validation and data integrity...
28 CFR 25.5 - Validation and data integrity of records in the system.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 28 Judicial Administration 1 2013-07-01 2013-07-01 false Validation and data integrity of records in the system. 25.5 Section 25.5 Judicial Administration DEPARTMENT OF JUSTICE DEPARTMENT OF JUSTICE INFORMATION SYSTEMS The National Instant Criminal Background Check System § 25.5 Validation and data integrity...
28 CFR 25.5 - Validation and data integrity of records in the system.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 28 Judicial Administration 1 2012-07-01 2012-07-01 false Validation and data integrity of records in the system. 25.5 Section 25.5 Judicial Administration DEPARTMENT OF JUSTICE DEPARTMENT OF JUSTICE INFORMATION SYSTEMS The National Instant Criminal Background Check System § 25.5 Validation and data integrity...
28 CFR 25.5 - Validation and data integrity of records in the system.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 28 Judicial Administration 1 2014-07-01 2014-07-01 false Validation and data integrity of records in the system. 25.5 Section 25.5 Judicial Administration DEPARTMENT OF JUSTICE DEPARTMENT OF JUSTICE INFORMATION SYSTEMS The National Instant Criminal Background Check System § 25.5 Validation and data integrity...
Integral criteria for large-scale multiple fingerprint solutions
NASA Astrophysics Data System (ADS)
Ushmaev, Oleg S.; Novikov, Sergey O.
2004-08-01
We propose the definition and analysis of the optimal integral similarity score criterion for large scale multmodal civil ID systems. Firstly, the general properties of score distributions for genuine and impostor matches for different systems and input devices are investigated. The empirical statistics was taken from the real biometric tests. Then we carry out the analysis of simultaneous score distributions for a number of combined biometric tests and primary for ultiple fingerprint solutions. The explicit and approximate relations for optimal integral score, which provides the least value of the FRR while the FAR is predefined, have been obtained. The results of real multiple fingerprint test show good correspondence with the theoretical results in the wide range of the False Acceptance and the False Rejection Rates.
The effect of cognitive load on hemispheric asymmetries in true and false memory.
Tat, Michael J; Azuma, Tamiko
2016-01-01
Studies examining hemispheric asymmetries in false memory have shown that the right hemisphere (RH) is more susceptible to false memories compared to the left hemisphere (LH). Theories suggest that hemispheric asymmetries in true and false memory may be due to differences in representational coding and the use of top-down mechanisms in each hemisphere. In the current study, the Deese-Roediger-McDermott false memory paradigm was used in conjunction with divided visual field presentation to examine the role of top-down mechanisms in hemispheric asymmetries of true and false memory. In Experiment 1, participants studied lists of related words while completing secondary cognitive load tasks. In Experiment 2, the secondary tasks were administered during memory retrieval instead of memory encoding. Results revealed that cognitive loads imposed during the study phase influenced veridical memory in the LH more than the RH, but cognitive loads imposed during retrieval did not influence veridical memory in either hemisphere. Surprisingly, false memory rates were not influenced by cognitive loads and were higher in the LH. These data provide evidence that, at least for veridical memory, top-down control mechanisms are used more readily for the encoding of information into memory in the LH compared to the RH.
Integrating new practices: a qualitative study of how hospital innovations become routine.
Brewster, Amanda L; Curry, Leslie A; Cherlin, Emily J; Talbert-Slagle, Kristina; Horwitz, Leora I; Bradley, Elizabeth H
2015-12-05
Hospital quality improvement efforts absorb substantial time and resources, but many innovations fail to integrate into organizational routines, undermining the potential to sustain the new practices. Despite a well-developed literature on the initial implementation of new practices, we have limited knowledge about the mechanisms by which integration occurs. We conducted a qualitative study using a purposive sample of hospitals that participated in the State Action on Avoidable Rehospitalizations (STAAR) initiative, a collaborative to reduce hospital readmissions that encouraged members to adopt new practices. We selected hospitals where risk-standardized readmission rates (RSRR) had improved (n = 7) or deteriorated (n = 3) over the course of the first 2 years of the STAAR initiative (2010-2011 to 2011-2012) and interviewed a range of staff at each site (90 total). We recruited hospitals until reaching theoretical saturation. The constant comparative method was used to conduct coding and identification of key themes. When innovations were successfully integrated, participants consistently reported that a small number of key staff held the innovation in place for as long as a year while more permanent integrating mechanisms began to work. Depending on characteristics of the innovation, one of three categories of integrating mechanisms eventually took over the role of holding new practices in place. Innovations that proved intrinsically rewarding to the staff, by making their jobs easier or more gratifying, became integrated through shifts in attitudes and norms over time. Innovations for which the staff did not perceive benefits to themselves were integrated through revised performance standards if the innovation involved complex tasks and through automation if the innovation involved simple tasks. Hospitals have an opportunity to promote the integration of new practices by planning for the extended effort required to hold a new practice in place while integration mechanisms take hold. By understanding how integrating mechanisms correspond to innovation characteristics, hospitals may be able to foster integrating mechanisms most likely to work for particular innovations.
46 CFR 167.15-40 - Integral fuel oil tank examinations-T/ALL.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 46 Shipping 7 2011-10-01 2011-10-01 false Integral fuel oil tank examinations-T/ALL. 167.15-40 Section 167.15-40 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS PUBLIC NAUTICAL SCHOOL SHIPS Inspections § 167.15-40 Integral fuel oil tank examinations—T/ALL. (a) Each...
Code of Federal Regulations, 2010 CFR
2010-04-01
... 25 Indians 1 2010-04-01 2010-04-01 false Can a school integrate Language Development programs into... Language Development Programs § 39.132 Can a school integrate Language Development programs into its regular instructional program? A school may offer Language Development programs to students as part of its...
46 CFR 167.15-40 - Integral fuel oil tank examinations-T/ALL.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 46 Shipping 7 2014-10-01 2014-10-01 false Integral fuel oil tank examinations-T/ALL. 167.15-40 Section 167.15-40 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS PUBLIC NAUTICAL SCHOOL SHIPS Inspections § 167.15-40 Integral fuel oil tank examinations—T/ALL. (a) Each...
46 CFR 167.15-40 - Integral fuel oil tank examinations-T/ALL.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 46 Shipping 7 2013-10-01 2013-10-01 false Integral fuel oil tank examinations-T/ALL. 167.15-40 Section 167.15-40 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS PUBLIC NAUTICAL SCHOOL SHIPS Inspections § 167.15-40 Integral fuel oil tank examinations—T/ALL. (a) Each...
46 CFR 167.15-40 - Integral fuel oil tank examinations-T/ALL.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 46 Shipping 7 2012-10-01 2012-10-01 false Integral fuel oil tank examinations-T/ALL. 167.15-40 Section 167.15-40 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS PUBLIC NAUTICAL SCHOOL SHIPS Inspections § 167.15-40 Integral fuel oil tank examinations—T/ALL. (a) Each...
49 CFR 571.304 - Standard No. 304; Compressed natural gas fuel container integrity.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 49 Transportation 6 2010-10-01 2010-10-01 false Standard No. 304; Compressed natural gas fuel... natural gas fuel container integrity. S1. Scope. This standard specifies requirements for the integrity of compressed natural gas (CNG), motor vehicle fuel containers. S2. Purpose. The purpose of this standard is to...
9 CFR 312.10 - Official mark for maintaining the identity and integrity of samples.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Official mark for maintaining the identity and integrity of samples. 312.10 Section 312.10 Animals and Animal Products FOOD SAFETY AND... § 312.10 Official mark for maintaining the identity and integrity of samples. The official mark for use...
9 CFR 381.112 - Official mark for maintaining the identity and integrity of samples.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Official mark for maintaining the identity and integrity of samples. 381.112 Section 381.112 Animals and Animal Products FOOD SAFETY AND... mark for maintaining the identity and integrity of samples. The official mark for use in sealing...
Code of Federal Regulations, 2011 CFR
2011-04-01
... 25 Indians 1 2011-04-01 2011-04-01 false Can a school integrate Language Development programs into... Language Development Programs § 39.132 Can a school integrate Language Development programs into its regular instructional program? A school may offer Language Development programs to students as part of its...
48 CFR 952.223-71 - Integration of environment, safety, and health into work planning and execution.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Integration of environment, safety, and health into work planning and execution. 952.223-71 Section 952.223-71 Federal Acquisition... Provisions and Clauses 952.223-71 Integration of environment, safety, and health into work planning and...
9 CFR 312.10 - Official mark for maintaining the identity and integrity of samples.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 9 Animals and Animal Products 2 2013-01-01 2013-01-01 false Official mark for maintaining the identity and integrity of samples. 312.10 Section 312.10 Animals and Animal Products FOOD SAFETY AND... § 312.10 Official mark for maintaining the identity and integrity of samples. The official mark for use...
9 CFR 381.112 - Official mark for maintaining the identity and integrity of samples.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 9 Animals and Animal Products 2 2013-01-01 2013-01-01 false Official mark for maintaining the identity and integrity of samples. 381.112 Section 381.112 Animals and Animal Products FOOD SAFETY AND... mark for maintaining the identity and integrity of samples. The official mark for use in sealing...
9 CFR 381.112 - Official mark for maintaining the identity and integrity of samples.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Official mark for maintaining the identity and integrity of samples. 381.112 Section 381.112 Animals and Animal Products FOOD SAFETY AND... mark for maintaining the identity and integrity of samples. The official mark for use in sealing...
9 CFR 312.10 - Official mark for maintaining the identity and integrity of samples.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 9 Animals and Animal Products 2 2014-01-01 2014-01-01 false Official mark for maintaining the identity and integrity of samples. 312.10 Section 312.10 Animals and Animal Products FOOD SAFETY AND... § 312.10 Official mark for maintaining the identity and integrity of samples. The official mark for use...
9 CFR 312.10 - Official mark for maintaining the identity and integrity of samples.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Official mark for maintaining the identity and integrity of samples. 312.10 Section 312.10 Animals and Animal Products FOOD SAFETY AND... § 312.10 Official mark for maintaining the identity and integrity of samples. The official mark for use...
9 CFR 381.112 - Official mark for maintaining the identity and integrity of samples.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 9 Animals and Animal Products 2 2014-01-01 2014-01-01 false Official mark for maintaining the identity and integrity of samples. 381.112 Section 381.112 Animals and Animal Products FOOD SAFETY AND... mark for maintaining the identity and integrity of samples. The official mark for use in sealing...
49 CFR 571.304 - Standard No. 304; Compressed natural gas fuel container integrity.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 49 Transportation 6 2011-10-01 2011-10-01 false Standard No. 304; Compressed natural gas fuel... natural gas fuel container integrity. S1. Scope. This standard specifies requirements for the integrity of compressed natural gas (CNG), motor vehicle fuel containers. S2. Purpose. The purpose of this standard is to...
Edwards, James P; Gerber, Urs; Schubert, Christian; Trejo, Maria Anabel; Weber, Axel
2018-04-01
We introduce two integral transforms of the quantum mechanical transition kernel that represent physical information about the path integral. These transforms can be interpreted as probability distributions on particle trajectories measuring respectively the relative contribution to the path integral from paths crossing a given spatial point (the hit function) and the likelihood of values of the line integral of the potential along a path in the ensemble (the path-averaged potential).
NASA Astrophysics Data System (ADS)
Edwards, James P.; Gerber, Urs; Schubert, Christian; Trejo, Maria Anabel; Weber, Axel
2018-04-01
We introduce two integral transforms of the quantum mechanical transition kernel that represent physical information about the path integral. These transforms can be interpreted as probability distributions on particle trajectories measuring respectively the relative contribution to the path integral from paths crossing a given spatial point (the hit function) and the likelihood of values of the line integral of the potential along a path in the ensemble (the path-averaged potential).
Hamann, Thorsten
2015-04-01
Some of the most important functions of plant cell walls are protection against biotic/abiotic stress and structural support during growth and development. A prerequisite for plant cell walls to perform these functions is the ability to perceive different types of stimuli in both qualitative and quantitative manners and initiate appropriate responses. The responses in turn involve adaptive changes in cellular and cell wall metabolism leading to modifications in the structures originally required for perception. While our knowledge about the underlying plant mechanisms is limited, results from Saccharomyces cerevisiae suggest the cell wall integrity maintenance mechanism represents an excellent example to illustrate how the molecular mechanisms responsible for stimulus perception, signal transduction and integration can function. Here I will review the available knowledge about the yeast cell wall integrity maintenance system for illustration purposes, summarize the limited knowledge available about the corresponding plant mechanism and discuss the relevance of the plant cell wall integrity maintenance mechanism in biotic stress responses. Copyright © 2014 Elsevier Ltd. All rights reserved.
ERIC Educational Resources Information Center
Murphy, Pat; Doherty, Paul
1998-01-01
Research has demonstrated that memory is prone to distortion and is occasionally untrustworthy. Explores the reasons for false memories and explains that memories are vulnerable to postevent information, which can be integrated into memories. False memories can also come from leading questions, word associations, and unconscious editing by the…
In vitro mechanical integrity of hydroxyapatite coated magnesium alloy.
Kannan, M Bobby; Orr, Lynnley
2011-08-01
The mechanical integrity of resorbable implants during service, especially in load bearing orthopaedic applications, is critical. The high degradation rate of resorbable magnesium and magnesium-based implants in body fluid may potentially cause premature in-service failure. In this study, a magnesium alloy (AZ91) was potentiostatically coated with hydroxyapatite at different cathodic voltages in an attempt to enhance the mechanical integrity. The mechanical integrity of the uncoated and hydroxyapatite coated alloys was evaluated after in vitro testing of the coated samples in simulated body fluid (SBF). The uncoated alloy showed 40% loss in the mechanical strength after five days exposure to SBF. However, the hydroxyapatite coated alloy exposed to SBF showed 20% improvement in the mechanical strength as compared to that of the uncoated alloy. The alloy coated potentiostatically at -2 V performed better than the -3 V coated alloy. The cross-sectional analysis of the coatings revealed relatively uniform coating thickness for the -2 V coated alloy, whereas the -3 V coated alloy exhibited areas of uneven coating. This can be attributed to the increase in hydrogen evolution on the alloy during -3 V coating as compared to -2 V coating. The scanning electron micrographs of the in vitro tested alloy revealed that hydroxyapatite coating significantly reduced the localized corrosion of the alloy, which is critical for better in-service mechanical integrity. Thus, the study suggests that the in vitro mechanical integrity of resorbable magnesium-based alloy can be improved by potentiostatic hydroxyapatite coating. © 2011 IOP Publishing Ltd
Integrating Thermal Tools Into the Mechanical Design Process
NASA Technical Reports Server (NTRS)
Tsuyuki, Glenn T.; Siebes, Georg; Novak, Keith S.; Kinsella, Gary M.
1999-01-01
The intent of mechanical design is to deliver a hardware product that meets or exceeds customer expectations, while reducing cycle time and cost. To this end, an integrated mechanical design process enables the idea of parallel development (concurrent engineering). This represents a shift from the traditional mechanical design process. With such a concurrent process, there are significant issues that have to be identified and addressed before re-engineering the mechanical design process to facilitate concurrent engineering. These issues also assist in the integration and re-engineering of the thermal design sub-process since it resides within the entire mechanical design process. With these issues in mind, a thermal design sub-process can be re-defined in a manner that has a higher probability of acceptance, thus enabling an integrated mechanical design process. However, the actual implementation is not always problem-free. Experience in applying the thermal design sub-process to actual situations provides the evidence for improvement, but more importantly, for judging the viability and feasibility of the sub-process.
48 CFR 34.202 - Integrated Baseline Reviews.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Integrated Baseline... SPECIAL CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 34.202... inherent risks in offerors'/contractors' performance plans and the underlying management control systems...
48 CFR 34.202 - Integrated Baseline Reviews.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Integrated Baseline... SPECIAL CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 34.202... inherent risks in offerors'/contractors' performance plans and the underlying management control systems...
48 CFR 34.202 - Integrated Baseline Reviews.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Integrated Baseline... SPECIAL CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 34.202... inherent risks in offerors'/contractors' performance plans and the underlying management control systems...
40 CFR 610.22 - Device integrity.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 29 2010-07-01 2010-07-01 false Device integrity. 610.22 Section 610.22 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) ENERGY POLICY FUEL ECONOMY RETROFIT DEVICES Test Procedures and Evaluation Criteria Evaluation Criteria for the Preliminary Analysis...
Method of mechanical quadratures for solving singular integral equations of various types
NASA Astrophysics Data System (ADS)
Sahakyan, A. V.; Amirjanyan, H. A.
2018-04-01
The method of mechanical quadratures is proposed as a common approach intended for solving the integral equations defined on finite intervals and containing Cauchy-type singular integrals. This method can be used to solve singular integral equations of the first and second kind, equations with generalized kernel, weakly singular equations, and integro-differential equations. The quadrature rules for several different integrals represented through the same coefficients are presented. This allows one to reduce the integral equations containing integrals of different types to a system of linear algebraic equations.
Spark-integrated propellant injector head with flashback barrier
NASA Technical Reports Server (NTRS)
Mungas, Gregory Stuart (Inventor); Fisher, David James (Inventor); Mungas, Christopher (Inventor)
2012-01-01
High performance propellants flow through specialized mechanical hardware that allows for effective and safe thermal decomposition and/or combustion of the propellants. By integrating a sintered metal component between a propellant feed source and the combustion chamber, an effective and reliable fuel injector head may be implemented. Additionally the fuel injector head design integrates a spark ignition mechanism that withstands extremely hot running conditions without noticeable spark mechanism degradation.
Eichengreen, Adva; Hoofien, Dan; Bachar, Eytan
2016-02-01
The concept of the false self has been used widely in psychoanalytic theory and practice but seldom in empirical research. In this empirically based study, elevated features of false-self defense were hypothetically associated with risk factors attendant on processes of rehabilitation and integration of children with disabilities, processes that encourage adaptation of the child to the able-bodied environment. Self-report questionnaires and in-depth interviews were conducted with 88 deaf and hard-of-hearing students and a comparison group of 88 hearing counterparts. Results demonstrate that despite the important contribution of rehabilitation and integration to the well-being of these children, these efforts may put the child at risk of increased use of the false-self defense. The empirical findings suggest two general theoretical conclusions: (1) The Winnicottian concept of the environment, usually confined to the parent-child relationship, can be understood more broadly as including cultural, social, and rehabilitational variables that both influence the parent-child relationship and operate independently of it. (2) The monolithic conceptualization of the false self may be more accurately unpacked to reveal two distinct subtypes: the compliant and the split false self. © 2016 by the American Psychoanalytic Association.
Romeo, Stefano; Chiandetti, Alessio; Siracusano, Alberto; Troisi, Alfonso
2014-08-15
Indirect evidence suggests partially common pathogenetic mechanisms for Neurological Soft Signs (NSS), neurocognition, and social cognition in schizophrenia. However, the possible association between NSS and mentalizing impairments has not yet been examined. In the present study, we assessed the ability to attribute mental states to others in patients with schizophrenia and predicted that the presence of theory of mind deficits would be significantly related to NSS. Participants were 90 clinically stable patients with a DSM-IV diagnosis of schizophrenia. NSS were assessed using the Neurological Evaluation Scale (NES). Theory of mind deficits were assessed using short verbal stories designed to measure false belief understanding. The findings of the study confirmed our hypothesis. Impaired sequencing of complex motor acts was the only neurological abnormality correlated with theory of mind deficits. By contrast, sensory integration, motor coordination and the NES Others subscale had no association with patients׳ ability to pass first- or second-order false belief tasks. If confirmed by future studies, the current findings provide the first preliminary evidence for the claim that specific NSS and theory of mind deficits may reflect overlapping neural substrates. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.
Exploration of parametric integrals related to a question of soil mechanics
NASA Astrophysics Data System (ADS)
Dana-Picard, Thierry; Zeitoun, David
2017-05-01
We study a 1-parameter family of trigonometric definite integrals, showing how the joint usage of Information and Communication Technologies and paper-and-pencil work lead to different outputs, revealing different mathematical meanings and different concrete meanings. This family of integrals is useful for describing a phenomenon in soil mechanics, whence the importance of such integrals in STEM education.
Integrating modeling and surveys for more effective assessments
A false dichotomy currently exists in monitoring that pits sample surveys based on probability designs against targeted monitoring of hand-picked sites. We maintain that judicious use of both, when designed to be integrated, produces assessments of greater value than either inde...
42 CFR 455.230 - Eligibility requirements.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 42 Public Health 4 2010-10-01 2010-10-01 false Eligibility requirements. 455.230 Section 455.230 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS PROGRAM INTEGRITY: MEDICAID Medicaid Integrity Program § 455.230...
48 CFR 1034.202 - Integrated Baseline Reviews.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Integrated Baseline... SPECIAL CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 1034.202... plans and the underlying management control systems, and it should formulate a plan to handle these...
48 CFR 1034.202 - Integrated Baseline Reviews.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Integrated Baseline... SPECIAL CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 1034.202... plans and the underlying management control systems, and it should formulate a plan to handle these...
48 CFR 1034.202 - Integrated Baseline Reviews.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Integrated Baseline... SPECIAL CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 1034.202... plans and the underlying management control systems, and it should formulate a plan to handle these...
GaN-on-diamond electronic device reliability: Mechanical and thermo-mechanical integrity
NASA Astrophysics Data System (ADS)
Liu, Dong; Sun, Huarui; Pomeroy, James W.; Francis, Daniel; Faili, Firooz; Twitchen, Daniel J.; Kuball, Martin
2015-12-01
The mechanical and thermo-mechanical integrity of GaN-on-diamond wafers used for ultra-high power microwave electronic devices was studied using a micro-pillar based in situ mechanical testing approach combined with an optical investigation of the stress and heat transfer across interfaces. We find the GaN/diamond interface to be thermo-mechanically stable, illustrating the potential for this material for reliable GaN electronic devices.
Naito, Mika; Seki, Yoshimi
2009-01-01
To investigate the relation between cognitive and affective social understanding, Japanese 4- to 8-year-olds received tasks of first- and second-order false beliefs and prosocial and self-presentational display rules. From 6 to 8 years, children comprehended display rules, as well as second-order false belief, using social pressures justifications decreasingly and motivational justifications with embedded perspectives increasingly with age. Although not related to either type of display across ages, second-order tasks were associated with both types of display tasks only at 8 years when examined in each age group. Results suggest that children base their second-order theory of mind and display rules understanding on distinct reasoning until middle childhood, during which time the originally distinct aspects of social understanding are integrated.
NASA Astrophysics Data System (ADS)
de Thomaz, A. A.; Faustino, W. M.; Fontes, A.; Fernandes, H. P.; Barjas-Castro, M. d. L.; Metze, K.; Giorgio, S.; Barbosa, L. C.; Cesar, C. L.
2007-09-01
The research in biomedical photonics is clearly evolving in the direction of the understanding of biological processes at the cell level. The spatial resolution to accomplish this task practically requires photonics tools. However, an integration of different photonic tools and a multimodal and functional approach will be necessary to access the mechanical and biochemical cell processes. This way we can observe mechanicaly triggered biochemical events or biochemicaly triggered mechanical events, or even observe simultaneously mechanical and biochemical events triggered by other means, e.g. electricaly. One great advantage of the photonic tools is its easiness for integration. Therefore, we developed such integrated tool by incorporating single and double Optical Tweezers with Confocal Single and Multiphoton Microscopies. This system can perform 2-photon excited fluorescence and Second Harmonic Generation microscopies together with optical manipulations. It also can acquire Fluorescence and SHG spectra of specific spots. Force, elasticity and viscosity measurements of stretched membranes can be followed by real time confocal microscopies. Also opticaly trapped living protozoas, such as leishmania amazonensis. Integration with CARS microscopy is under way. We will show several examples of the use of such integrated instrument and its potential to observe mechanical and biochemical processes at cell level.
Importance of Air Absorption During Mechanical Integrity Testing
NASA Astrophysics Data System (ADS)
Arnold, Fredric C.
1990-11-01
Wells used for injection of liquid industrial waste into deep saline aquifers are required to be periodically tested for mechanical integrity. A generally accepted method to demonstrate mechanical integrity is to pressurize the casing-tubing annulus and monitor any decline in pressure. If air is used to pressurize the annulus, uncertainty may exist in differentiating between absorption of air into water in the annulus and loss of pressure due to the absence of mechanical integrity. An analytical model of air absorbance has been derived and used to quantify the pressure decline due to dissolving and diffusion of the air in annular water. A parameteric study was made to determine when annular pressure decline due to absorption of air is significant.
NASA Astrophysics Data System (ADS)
Fine, Dana S.; Sawin, Stephen
2017-01-01
Feynman's time-slicing construction approximates the path integral by a product, determined by a partition of a finite time interval, of approximate propagators. This paper formulates general conditions to impose on a short-time approximation to the propagator in a general class of imaginary-time quantum mechanics on a Riemannian manifold which ensure that these products converge. The limit defines a path integral which agrees pointwise with the heat kernel for a generalized Laplacian. The result is a rigorous construction of the propagator for supersymmetric quantum mechanics, with potential, as a path integral. Further, the class of Laplacians includes the square of the twisted Dirac operator, which corresponds to an extension of N = 1/2 supersymmetric quantum mechanics. General results on the rate of convergence of the approximate path integrals suffice in this case to derive the local version of the Atiyah-Singer index theorem.
Automatic detection, tracking and sensor integration
NASA Astrophysics Data System (ADS)
Trunk, G. V.
1988-06-01
This report surveys the state of the art of automatic detection, tracking, and sensor integration. In the area of detection, various noncoherent integrators such as the moving window integrator, feedback integrator, two-pole filter, binary integrator, and batch processor are discussed. Next, the three techniques for controlling false alarms, adapting thresholds, nonparametric detectors, and clutter maps are presented. In the area of tracking, a general outline is given of a track-while-scan system, and then a discussion is presented of the file system, contact-entry logic, coordinate systems, tracking filters, maneuver-following logic, tracking initiating, track-drop logic, and correlation procedures. Finally, in the area of multisensor integration the problems of colocated-radar integration, multisite-radar integration, radar-IFF integration, and radar-DF bearing strobe integration are treated.
46 CFR 154.1860 - Integral tanks: Cargo colder than −10 °C (14 °F).
Code of Federal Regulations, 2013 CFR
2013-10-01
... 46 Shipping 5 2013-10-01 2013-10-01 false Integral tanks: Cargo colder than â10 °C (14 °F). 154....1860 Integral tanks: Cargo colder than −10 °C (14 °F). The master shall ensure that an integral tank does not carry a cargo colder than −10 °C (14 °F) unless that carriage is specially approved by the...
46 CFR 154.1860 - Integral tanks: Cargo colder than −10 °C (14 °F).
Code of Federal Regulations, 2011 CFR
2011-10-01
... 46 Shipping 5 2011-10-01 2011-10-01 false Integral tanks: Cargo colder than â10 °C (14 °F). 154....1860 Integral tanks: Cargo colder than −10 °C (14 °F). The master shall ensure that an integral tank does not carry a cargo colder than −10 °C (14 °F) unless that carriage is specially approved by the...
46 CFR 154.1860 - Integral tanks: Cargo colder than −10 °C (14 °F).
Code of Federal Regulations, 2012 CFR
2012-10-01
... 46 Shipping 5 2012-10-01 2012-10-01 false Integral tanks: Cargo colder than â10 °C (14 °F). 154....1860 Integral tanks: Cargo colder than −10 °C (14 °F). The master shall ensure that an integral tank does not carry a cargo colder than −10 °C (14 °F) unless that carriage is specially approved by the...
46 CFR 154.1860 - Integral tanks: Cargo colder than −10 °C (14 °F).
Code of Federal Regulations, 2010 CFR
2010-10-01
... 46 Shipping 5 2010-10-01 2010-10-01 false Integral tanks: Cargo colder than â10 °C (14 °F). 154....1860 Integral tanks: Cargo colder than −10 °C (14 °F). The master shall ensure that an integral tank does not carry a cargo colder than −10 °C (14 °F) unless that carriage is specially approved by the...
46 CFR 154.1860 - Integral tanks: Cargo colder than −10 °C (14 °F).
Code of Federal Regulations, 2014 CFR
2014-10-01
... 46 Shipping 5 2014-10-01 2014-10-01 false Integral tanks: Cargo colder than â10 °C (14 °F). 154....1860 Integral tanks: Cargo colder than −10 °C (14 °F). The master shall ensure that an integral tank does not carry a cargo colder than −10 °C (14 °F) unless that carriage is specially approved by the...
oPOSSUM: identification of over-represented transcription factor binding sites in co-expressed genes
Ho Sui, Shannan J.; Mortimer, James R.; Arenillas, David J.; Brumm, Jochen; Walsh, Christopher J.; Kennedy, Brian P.; Wasserman, Wyeth W.
2005-01-01
Targeted transcript profiling studies can identify sets of co-expressed genes; however, identification of the underlying functional mechanism(s) is a significant challenge. Established methods for the analysis of gene annotations, particularly those based on the Gene Ontology, can identify functional linkages between genes. Similar methods for the identification of over-represented transcription factor binding sites (TFBSs) have been successful in yeast, but extension to human genomics has largely proved ineffective. Creation of a system for the efficient identification of common regulatory mechanisms in a subset of co-expressed human genes promises to break a roadblock in functional genomics research. We have developed an integrated system that searches for evidence of co-regulation by one or more transcription factors (TFs). oPOSSUM combines a pre-computed database of conserved TFBSs in human and mouse promoters with statistical methods for identification of sites over-represented in a set of co-expressed genes. The algorithm successfully identified mediating TFs in control sets of tissue-specific genes and in sets of co-expressed genes from three transcript profiling studies. Simulation studies indicate that oPOSSUM produces few false positives using empirically defined thresholds and can tolerate up to 50% noise in a set of co-expressed genes. PMID:15933209
Mechanical stimulation enhances integration in an in vitro model of cartilage repair.
Theodoropoulos, John S; DeCroos, Amritha J N; Petrera, Massimo; Park, Sam; Kandel, Rita A
2016-06-01
(1) To characterize the effects of mechanical stimulation on the integration of a tissue-engineered construct in terms of histology, biochemistry and biomechanical properties; (2) to identify whether cells of the implant or host tissue were critical to implant integration; and (3) to study cells believed to be involved in lateral integration of tissue-engineered cartilage to host cartilage. We hypothesized that mechanical stimulation would enhance the integration of the repair implant with host cartilage in an in vitro integration model. Articular cartilage was harvested from 6- to 9-month-old bovine metacarpal-phalangeal joints. Constructs composed of tissue-engineered cartilage implanted into host cartilage were placed in spinner bioreactors and maintained on a magnetic stir plate at either 0 (static control) or 90 (experimental) rotations per minute (RPM). The constructs from both the static and spinner bioreactors were harvested after either 2 or 4 weeks of culture and evaluated histologically, biochemically, biomechanically and for gene expression. The extent and strength of integration between tissue-engineered cartilage and native cartilage improved significantly with both time and mechanical stimulation. Integration did not occur if the implant was not viable. The presence of stimulation led to a significant increase in collagen content in the integration zone between host and implant at 2 weeks. The gene profile of cells in the integration zone differs from host cartilage demonstrating an increase in the expression of membrane type 1 matrix metalloproteinase (MT1-MMP), aggrecan and type II collagen. This study shows that the integration of in vitro tissue-engineered implants with host tissue improves with mechanical stimulation. The findings of this study suggests that consideration should be given to implementing early loading (mechanical stimulation) into future in vivo studies investigating the long-term viability and integration of tissue-engineered cartilage for the treatment of cartilage injuries. This could simply be done through the use of continuous passive motion (CPM) in the post-operative period or through a more complex and structured rehabilitation program with a gradual increase in forces across the joint over time.
42 CFR 460.68 - Program integrity.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 42 Public Health 4 2014-10-01 2014-10-01 false Program integrity. 460.68 Section 460.68 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... of criminal offenses related to their involvement in Medicaid, Medicare, other health insurance or...
42 CFR 460.68 - Program integrity.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 42 Public Health 4 2010-10-01 2010-10-01 false Program integrity. 460.68 Section 460.68 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... of criminal offenses related to their involvement in Medicaid, Medicare, other health insurance or...
42 CFR 460.68 - Program integrity.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 42 Public Health 4 2011-10-01 2011-10-01 false Program integrity. 460.68 Section 460.68 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... of criminal offenses related to their involvement in Medicaid, Medicare, other health insurance or...
42 CFR 460.68 - Program integrity.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 42 Public Health 4 2013-10-01 2013-10-01 false Program integrity. 460.68 Section 460.68 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... of criminal offenses related to their involvement in Medicaid, Medicare, other health insurance or...
42 CFR 460.68 - Program integrity.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 42 Public Health 4 2012-10-01 2012-10-01 false Program integrity. 460.68 Section 460.68 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... of criminal offenses related to their involvement in Medicaid, Medicare, other health insurance or...
14 CFR 1214.810 - Integration of payloads.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false Integration of payloads. 1214.810 Section 1214.810 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION SPACE FLIGHT Reimbursement... performing the following typical Spacelab-payload mission management functions: (1) Analytical design of the...
14 CFR 1214.810 - Integration of payloads.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 14 Aeronautics and Space 5 2013-01-01 2013-01-01 false Integration of payloads. 1214.810 Section 1214.810 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION SPACE FLIGHT Reimbursement... performing the following typical Spacelab-payload mission management functions: (1) Analytical design of the...
49 CFR 1544.409 - Integrity of screener tests.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 49 Transportation 9 2014-10-01 2014-10-01 false Integrity of screener tests. 1544.409 Section 1544.409 Transportation Other Regulations Relating to Transportation (Continued) TRANSPORTATION SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY AIRCRAFT OPERATOR SECURITY: AIR CARRIERS AND COMMERCIAL OPERATORS Screener...
Sarpe, Vladimir; Rafiei, Atefeh; Hepburn, Morgan; Ostan, Nicholas; Schryvers, Anthony B.; Schriemer, David C.
2016-01-01
The Mass Spec Studio package was designed to support the extraction of hydrogen-deuterium exchange and covalent labeling data for a range of mass spectrometry (MS)-based workflows, to integrate with restraint-driven protein modeling activities. In this report, we present an extension of the underlying Studio framework and provide a plug-in for crosslink (XL) detection. To accommodate flexibility in XL methods and applications, while maintaining efficient data processing, the plug-in employs a peptide library reduction strategy via a presearch of the tandem-MS data. We demonstrate that prescoring linear unmodified peptide tags using a probabilistic approach substantially reduces search space by requiring both crosslinked peptides to generate sparse data attributable to their linear forms. The method demonstrates highly sensitive crosslink peptide identification with a low false positive rate. Integration with a Haddock plug-in provides a resource that can combine multiple sources of data for protein modeling activities. We generated a structural model of porcine transferrin bound to TbpB, a membrane-bound receptor essential for iron acquisition in Actinobacillus pleuropneumoniae. Using mutational data and crosslinking restraints, we confirm the mechanism by which TbpB recognizes the iron-loaded form of transferrin, and note the requirement for disparate sources of restraint data for accurate model construction. The software plugin is freely available at www.msstudio.ca. PMID:27412762
The role of right frontal brain regions in integration of spatial relation.
Han, Jiahui; Cao, Bihua; Cao, Yunfei; Gao, Heming; Li, Fuhong
2016-06-01
Previous studies have explored the neural mechanisms of spatial reasoning on a two-dimensional (2D) plane; however, it remains unclear how spatial reasoning is conducted in a three-dimensional (3D) condition. In the present study, we presented 3D geometric objects to 16 adult participants, and asked them to process the spatial relationship between different corners of the geometric objects. In premise-1, the first two corners of a geometric shape (e.g., A vs. B) were displayed. In premise-2, the second and third corners (e.g., B vs. C) were displayed. After integrating the two premises, participants were required to infer the spatial relationship between the first and the third corners (e.g., A and C). Finally, the participants were presented with a conclusion object, and they were required to judge whether the conclusion was true or false based on their inference. The event-related potential evoked by premise-2 revealed that (1) compared with 2D spatial reasoning, 3D reasoning elicited a smaller P3b component, and (2) in the right frontal areas, increased negativities were found in the 3D condition during the N400 and late negative components (LNC). These findings imply that higher brain activity in the right frontal brain regions were related with the integration and maintenance of spatial information in working memory for reasoning. Copyright © 2016 Elsevier Ltd. All rights reserved.
Sarpe, Vladimir; Rafiei, Atefeh; Hepburn, Morgan; Ostan, Nicholas; Schryvers, Anthony B; Schriemer, David C
2016-09-01
The Mass Spec Studio package was designed to support the extraction of hydrogen-deuterium exchange and covalent labeling data for a range of mass spectrometry (MS)-based workflows, to integrate with restraint-driven protein modeling activities. In this report, we present an extension of the underlying Studio framework and provide a plug-in for crosslink (XL) detection. To accommodate flexibility in XL methods and applications, while maintaining efficient data processing, the plug-in employs a peptide library reduction strategy via a presearch of the tandem-MS data. We demonstrate that prescoring linear unmodified peptide tags using a probabilistic approach substantially reduces search space by requiring both crosslinked peptides to generate sparse data attributable to their linear forms. The method demonstrates highly sensitive crosslink peptide identification with a low false positive rate. Integration with a Haddock plug-in provides a resource that can combine multiple sources of data for protein modeling activities. We generated a structural model of porcine transferrin bound to TbpB, a membrane-bound receptor essential for iron acquisition in Actinobacillus pleuropneumoniae Using mutational data and crosslinking restraints, we confirm the mechanism by which TbpB recognizes the iron-loaded form of transferrin, and note the requirement for disparate sources of restraint data for accurate model construction. The software plugin is freely available at www.msstudio.ca. © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 32 National Defense 1 2010-07-01 2010-07-01 false What Is the Civil-Military Integration Policy That Is the Basis for Technology Investment Agreements? A Appendix A to Part 37 National Defense... INVESTMENT AGREEMENTS Pt. 37, App. A Appendix A to Part 37—What Is the Civil-Military Integration Policy That...
Code of Federal Regulations, 2010 CFR
2010-04-01
... 25 Indians 1 2010-04-01 2010-04-01 false May a tribe integrate Job Placement and Training funds... THE INTERIOR HUMAN SERVICES JOB PLACEMENT AND TRAINING PROGRAM General Applicability § 26.22 May a tribe integrate Job Placement and Training funds into its Public Law 102-477 Plan? Yes, Indian tribes...
Systems pharmacology augments drug safety surveillance
Lorberbaum, Tal; Nasir, Mavra; Keiser, Michael J.; Vilar, Santiago; Hripcsak, George; Tatonetti, Nicholas P.
2014-01-01
Small molecule drugs are the foundation of modern medical practice yet their use is limited by the onset of unexpected and severe adverse events (AEs). Regulatory agencies rely on post-marketing surveillance to monitor safety once drugs are approved for clinical use. Despite advances in pharmacovigilance methods that address issues of confounding bias, clinical data of AEs are inherently noisy. Systems pharmacology– the integration of systems biology and chemical genomics – can illuminate drug mechanisms of action. We hypothesize that these data can improve drug safety surveillance by highlighting drugs with a mechanistic connection to the target phenotype (enriching true positives) and filtering those that do not (depleting false positives). We present an algorithm, the modular assembly of drug safety subnetworks (MADSS), to combine systems pharmacology and pharmacovigilance data and significantly improve drug safety monitoring for four clinically relevant adverse drug reactions. PMID:25670520
Integrated Software Health Management for Aircraft GN and C
NASA Technical Reports Server (NTRS)
Schumann, Johann; Mengshoel, Ole
2011-01-01
Modern aircraft rely heavily on dependable operation of many safety-critical software components. Despite careful design, verification and validation (V&V), on-board software can fail with disastrous consequences if it encounters problematic software/hardware interaction or must operate in an unexpected environment. We are using a Bayesian approach to monitor the software and its behavior during operation and provide up-to-date information about the health of the software and its components. The powerful reasoning mechanism provided by our model-based Bayesian approach makes reliable diagnosis of the root causes possible and minimizes the number of false alarms. Compilation of the Bayesian model into compact arithmetic circuits makes SWHM feasible even on platforms with limited CPU power. We show initial results of SWHM on a small simulator of an embedded aircraft software system, where software and sensor faults can be injected.
Formulation of D-brane Dynamics
NASA Astrophysics Data System (ADS)
Evans, Thomas
2012-03-01
It is the purpose of this paper (within the context of STS rules & guidelines ``research report'') to formulate a statistical-mechanical form of D-brane dynamics. We consider first the path integral formulation of quantum mechanics, and extend this to a path-integral formulation of D-brane mechanics, summing over all the possible path integral sectors of R-R, NS charged states. We then investigate this generalization utilizing a path-integral formulation summing over all the possible path integral sectors of R-R charged states, calculated from the mean probability tree-level amplitude of type I, IIA, and IIB strings, serving as a generalization of all strings described by D-branes. We utilize this generalization to study black holes in regimes where the initial D-brane system is legitimate, and further this generalization to look at information loss near regions of nonlocality on a non-ordinary event horizon. We see here that in these specific regimes, we can calculate a path integral formulation, as describing D0-brane mechanics, tracing the dissipation of entropy throughout the event horizon. This is used to study the information paradox, and to propose a resolution between the phenomena and the correct and expected quantum mechanical description. This is done as our path integral throughout entropy entering the event horizon effectively and correctly encodes the initial state in subtle correlations in the Hawking radiation.
49 CFR 1546.409 - Integrity of screener tests.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 49 Transportation 9 2014-10-01 2014-10-01 false Integrity of screener tests. 1546.409 Section 1546.409 Transportation Other Regulations Relating to Transportation (Continued) TRANSPORTATION SECURITY ADMINISTRATION, DEPARTMENT OF HOMELAND SECURITY CIVIL AVIATION SECURITY FOREIGN AIR CARRIER SECURITY Screener Qualifications When the Foreign Air...
41 CFR 102-79.105 - What is the Integrated Workplace?
Code of Federal Regulations, 2012 CFR
2012-01-01
... 41 Public Contracts and Property Management 3 2012-01-01 2012-01-01 false What is the Integrated Workplace? 102-79.105 Section 102-79.105 Public Contracts and Property Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION REAL PROPERTY 79-ASSIGNMENT AND...
41 CFR 102-79.105 - What is the Integrated Workplace?
Code of Federal Regulations, 2014 CFR
2014-01-01
... 41 Public Contracts and Property Management 3 2014-01-01 2014-01-01 false What is the Integrated Workplace? 102-79.105 Section 102-79.105 Public Contracts and Property Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION REAL PROPERTY 79-ASSIGNMENT AND...
41 CFR 102-79.105 - What is the Integrated Workplace?
Code of Federal Regulations, 2013 CFR
2013-07-01
... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false What is the Integrated Workplace? 102-79.105 Section 102-79.105 Public Contracts and Property Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION REAL PROPERTY 79-ASSIGNMENT AND...
Code of Federal Regulations, 2010 CFR
2010-10-01
... 45 Public Welfare 1 2010-10-01 2010-10-01 false Immunity. 61.16 Section 61.16 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION HEALTHCARE INTEGRITY AND PROTECTION DATA BANK... Information by the Healthcare Integrity and Protection Data Bank § 61.16 Immunity. Individuals, entities or...
Code of Federal Regulations, 2012 CFR
2012-10-01
... 45 Public Welfare 1 2012-10-01 2012-10-01 false Immunity. 61.16 Section 61.16 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION HEALTHCARE INTEGRITY AND PROTECTION DATA BANK... Information by the Healthcare Integrity and Protection Data Bank § 61.16 Immunity. Individuals, entities or...
Code of Federal Regulations, 2011 CFR
2011-10-01
... 45 Public Welfare 1 2011-10-01 2011-10-01 false Immunity. 61.16 Section 61.16 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION HEALTHCARE INTEGRITY AND PROTECTION DATA BANK... Information by the Healthcare Integrity and Protection Data Bank § 61.16 Immunity. Individuals, entities or...
16 CFR 1511.5 - Structural integrity tests.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Structural integrity tests. 1511.5 Section 1511.5 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION FEDERAL HAZARDOUS SUBSTANCES ACT... lowest position in the cylinder. If the uppermost edge of the component or fragment is below the plane of...
25 CFR 163.11 - Forest management planning and sustained yield management.
Code of Federal Regulations, 2010 CFR
2010-04-01
... implementation of integrated resource management plans which provide coordination for the comprehensive management of all natural resources on Indian land. If the integrated resource management planning process... 25 Indians 1 2010-04-01 2010-04-01 false Forest management planning and sustained yield management...
46 CFR 111.105-5 - System integrity.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 46 Shipping 4 2010-10-01 2010-10-01 false System integrity. 111.105-5 Section 111.105-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL... individual electrical installation in a hazardous location must comply specifically with Articles 500-505 of...
Micro-computed tomography of false starts produced on bone by different hand-saws.
Pelletti, Guido; Viel, Guido; Fais, Paolo; Viero, Alessia; Visentin, Sindi; Miotto, Diego; Montisci, Massimo; Cecchetto, Giovanni; Giraudo, Chiara
2017-05-01
The analysis of macro- and microscopic characteristics of saw marks on bones can provide useful information about the class of the tool utilized to produce the injury. The aim of the present study was to test micro-computed tomography (micro-CT) for the analysis of false starts experimentally produced on 32 human bone sections using 4 different hand-saws in order to verify the potential utility of micro-CT for distinguishing false starts produced by different saws and to correlate the morphology of the tool with that of the bone mark. Each sample was analysed through stereomicroscopy and micro-CT. Stereomicroscopic analysis allowed the identification of the false starts and the detection of the number of tool marks left by each saw. Micro-CT scans, through the integration of 3D renders and multiplanar reconstructions (MPR), allowed the identification of the shape of each false start correlating it to the injuring tool. Our results suggest that micro-CT could be a useful technique for assessing false starts produced by different classes of saws, providing accurate morphological profiles of the bone marks with all the advantages of high resolution 3D imaging (e.g., high accuracy, non-destructive analysis, preservation and documentation of evidence). However, further studies are necessary to integrate qualitative data with quantitative metrical analysis in order to further characterize the false start and the related injuring tool. Copyright © 2017 Elsevier B.V. All rights reserved.
Bobby Kannan, M; Singh Raman, R K; Witte, F; Blawert, C; Dietzel, W
2011-02-01
Applications of magnesium alloys as biodegradable orthopaedic implants are critically dependent on the mechanical integrity of the implant during service. In this study, the mechanical integrity of an AZ91 magnesium alloy was studied using a constant extension rate tensile (CERT) method. The samples in two different geometries that is, circumferentially notched (CN), and circumferentially notched and fatigue cracked (CNFC), were tested in air and in simulated body fluid (SBF). The test results show that the mechanical integrity of the AZ91 magnesium alloy decreased substantially (∼50%) in both the CN and CNFC samples exposed to SBF. Fracture surface analysis revealed secondary cracks suggesting stress corrosion cracking susceptibility of the alloy in SBF. Copyright © 2010 Wiley Periodicals, Inc.
On the Conference as an Integrating Mechanism.
ERIC Educational Resources Information Center
Feldman, Wendy; Johnson, J. David
Due to their increasing complexity, modern organizations require more effective integrating mechanisms. The conference, which can be a very positive thing for an organization as it provides rewards for members while performing a crucial communication function for the whole, is one possible mechanism. Communication is not only an inherent part of…
NASA Astrophysics Data System (ADS)
Barra, Adriano; Contucci, Pierluigi; Sandell, Rickard; Vernia, Cecilia
2014-02-01
How does immigrant integration in a country change with immigration density? Guided by a statistical mechanics perspective we propose a novel approach to this problem. The analysis focuses on classical integration quantifiers such as the percentage of jobs (temporary and permanent) given to immigrants, mixed marriages, and newborns with parents of mixed origin. We find that the average values of different quantifiers may exhibit either linear or non-linear growth on immigrant density and we suggest that social action, a concept identified by Max Weber, causes the observed non-linearity. Using the statistical mechanics notion of interaction to quantitatively emulate social action, a unified mathematical model for integration is proposed and it is shown to explain both growth behaviors observed. The linear theory instead, ignoring the possibility of interaction effects would underestimate the quantifiers up to 30% when immigrant densities are low, and overestimate them as much when densities are high. The capacity to quantitatively isolate different types of integration mechanisms makes our framework a suitable tool in the quest for more efficient integration policies.
21 CFR 882.1880 - Evoked response mechanical stimulator.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Evoked response mechanical stimulator. 882.1880... mechanical stimulator. (a) Identification. An evoked response mechanical stimulator is a device used to produce a mechanical stimulus or a series of mechanical stimuli for the purpose of measuring a patient's...
46 CFR 154.1200 - Mechanical ventilation system: General.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 46 Shipping 5 2010-10-01 2010-10-01 false Mechanical ventilation system: General. 154.1200 Section... Equipment Cargo Area: Mechanical Ventilation System § 154.1200 Mechanical ventilation system: General. (a... cargo handling equipment must have a fixed, exhaust-type mechanical ventilation system. (b) The...
42 CFR 93.217 - Office of Research Integrity or ORI.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 42 Public Health 1 2011-10-01 2011-10-01 false Office of Research Integrity or ORI. 93.217 Section 93.217 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH ASSESSMENTS AND HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE...
14 CFR § 1214.810 - Integration of payloads.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 14 Aeronautics and Space 5 2014-01-01 2014-01-01 false Integration of payloads. § 1214.810 Section § 1214.810 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION SPACE FLIGHT... performing the following typical Spacelab-payload mission management functions: (1) Analytical design of the...
48 CFR 334.202 - Integrated Baseline Reviews (IBRs).
Code of Federal Regulations, 2014 CFR
2014-10-01
... rationale for a pre-award IBR, including an assessment of the impact on the source selection schedule and... 48 Federal Acquisition Regulations System 4 2014-10-01 2014-10-01 false Integrated Baseline Reviews (IBRs). 334.202 Section 334.202 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES...
48 CFR 334.202 - Integrated Baseline Reviews (IBRs).
Code of Federal Regulations, 2013 CFR
2013-10-01
... rationale for a pre-award IBR, including an assessment of the impact on the source selection schedule and... 48 Federal Acquisition Regulations System 4 2013-10-01 2013-10-01 false Integrated Baseline Reviews (IBRs). 334.202 Section 334.202 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES...
48 CFR 334.202 - Integrated Baseline Reviews (IBRs).
Code of Federal Regulations, 2011 CFR
2011-10-01
... rationale for a pre-award IBR, including an assessment of the impact on the source selection schedule and... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Integrated Baseline Reviews (IBRs). 334.202 Section 334.202 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES...
48 CFR 334.202 - Integrated Baseline Reviews (IBRs).
Code of Federal Regulations, 2012 CFR
2012-10-01
... rationale for a pre-award IBR, including an assessment of the impact on the source selection schedule and... 48 Federal Acquisition Regulations System 4 2012-10-01 2012-10-01 false Integrated Baseline Reviews (IBRs). 334.202 Section 334.202 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES...
48 CFR 334.202 - Integrated Baseline Reviews (IBRs).
Code of Federal Regulations, 2010 CFR
2010-10-01
... rationale for a pre-award IBR, including an assessment of the impact on the source selection schedule and... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Integrated Baseline Reviews (IBRs). 334.202 Section 334.202 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES...
ERIC Educational Resources Information Center
Lassonde, Karla A.; Kolquist, Molly; Vergin, Megan
2017-01-01
Refutation-style texts have been considered a viable strategy for changing psychological misconceptions. The current study aims to integrate refutation-style texts into a classroom-based method of learning. Psychology students were administered a true/false misconception survey and then viewed several refutation-style poster presentations…
48 CFR 208.7000 - Scope of subpart.
Code of Federal Regulations, 2010 CFR
2010-10-01
... (commodity assignments are listed in PGI 208.7006); or (b) The Integrated Materiel Management Program (assignments are in DoD 4140.26-M, Defense Integrated Materiel Management Manual for Consumable Items). [56 FR... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Scope of subpart. 208.7000...
48 CFR 208.7000 - Scope of subpart.
Code of Federal Regulations, 2011 CFR
2011-10-01
... (commodity assignments are listed in PGI 208.7006); or (b) The Integrated Materiel Management Program (assignments are in DoD 4140.26-M, Defense Integrated Materiel Management Manual for Consumable Items). [56 FR... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Scope of subpart. 208.7000...
48 CFR 208.7000 - Scope of subpart.
Code of Federal Regulations, 2013 CFR
2013-10-01
... (commodity assignments are listed in PGI 208.7006); or (b) The Integrated Materiel Management Program (assignments are in DoD 4140.26-M, Defense Integrated Materiel Management Manual for Consumable Items). [56 FR... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Scope of subpart. 208.7000...
48 CFR 208.7000 - Scope of subpart.
Code of Federal Regulations, 2014 CFR
2014-10-01
... (commodity assignments are listed in PGI 208.7006); or (b) The Integrated Materiel Management Program (assignments are in DoD 4140.26-M, Defense Integrated Materiel Management Manual for Consumable Items). [56 FR... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Scope of subpart. 208.7000...
48 CFR 208.7000 - Scope of subpart.
Code of Federal Regulations, 2012 CFR
2012-10-01
... (commodity assignments are listed in PGI 208.7006); or (b) The Integrated Materiel Management Program (assignments are in DoD 4140.26-M, Defense Integrated Materiel Management Manual for Consumable Items). [56 FR... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Scope of subpart. 208.7000...
28 CFR 20.37 - Responsibility for accuracy, completeness, currency, and integrity.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 28 Judicial Administration 1 2013-07-01 2013-07-01 false Responsibility for accuracy, completeness, currency, and integrity. 20.37 Section 20.37 Judicial Administration DEPARTMENT OF JUSTICE CRIMINAL JUSTICE INFORMATION SYSTEMS Federal Systems and Exchange of Criminal History Record Information § 20.37 Responsibility...
28 CFR 20.37 - Responsibility for accuracy, completeness, currency, and integrity.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 28 Judicial Administration 1 2012-07-01 2012-07-01 false Responsibility for accuracy, completeness, currency, and integrity. 20.37 Section 20.37 Judicial Administration DEPARTMENT OF JUSTICE CRIMINAL JUSTICE INFORMATION SYSTEMS Federal Systems and Exchange of Criminal History Record Information § 20.37 Responsibility...
28 CFR 20.37 - Responsibility for accuracy, completeness, currency, and integrity.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 28 Judicial Administration 1 2014-07-01 2014-07-01 false Responsibility for accuracy, completeness, currency, and integrity. 20.37 Section 20.37 Judicial Administration DEPARTMENT OF JUSTICE CRIMINAL JUSTICE INFORMATION SYSTEMS Federal Systems and Exchange of Criminal History Record Information § 20.37 Responsibility...
28 CFR 20.37 - Responsibility for accuracy, completeness, currency, and integrity.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 28 Judicial Administration 1 2011-07-01 2011-07-01 false Responsibility for accuracy, completeness, currency, and integrity. 20.37 Section 20.37 Judicial Administration DEPARTMENT OF JUSTICE CRIMINAL JUSTICE INFORMATION SYSTEMS Federal Systems and Exchange of Criminal History Record Information § 20.37 Responsibility...
Code of Federal Regulations, 2013 CFR
2013-01-01
... 16 Commercial Practices 1 2013-01-01 2013-01-01 false Confidentiality, security, and integrity of personal information collected from children. 312.8 Section 312.8 Commercial Practices FEDERAL TRADE COMMISSION REGULATIONS UNDER SPECIFIC ACTS OF CONGRESS CHILDREN'S ONLINE PRIVACY PROTECTION RULE § 312.8...
Code of Federal Regulations, 2010 CFR
2010-01-01
... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Confidentiality, security, and integrity of personal information collected from children. 312.8 Section 312.8 Commercial Practices FEDERAL TRADE COMMISSION REGULATIONS UNDER SPECIFIC ACTS OF CONGRESS CHILDREN'S ONLINE PRIVACY PROTECTION RULE § 312.8...
Code of Federal Regulations, 2011 CFR
2011-01-01
... 16 Commercial Practices 1 2011-01-01 2011-01-01 false Confidentiality, security, and integrity of personal information collected from children. 312.8 Section 312.8 Commercial Practices FEDERAL TRADE COMMISSION REGULATIONS UNDER SPECIFIC ACTS OF CONGRESS CHILDREN'S ONLINE PRIVACY PROTECTION RULE § 312.8...
Code of Federal Regulations, 2012 CFR
2012-01-01
... 16 Commercial Practices 1 2012-01-01 2012-01-01 false Confidentiality, security, and integrity of personal information collected from children. 312.8 Section 312.8 Commercial Practices FEDERAL TRADE COMMISSION REGULATIONS UNDER SPECIFIC ACTS OF CONGRESS CHILDREN'S ONLINE PRIVACY PROTECTION RULE § 312.8...
Code of Federal Regulations, 2014 CFR
2014-01-01
... 16 Commercial Practices 1 2014-01-01 2014-01-01 false Confidentiality, security, and integrity of personal information collected from children. 312.8 Section 312.8 Commercial Practices FEDERAL TRADE COMMISSION REGULATIONS UNDER SPECIFIC ACTS OF CONGRESS CHILDREN'S ONLINE PRIVACY PROTECTION RULE § 312.8...
45 CFR 61.12 - Requesting information from the Healthcare Integrity and Protection Data Bank.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 45 Public Welfare 1 2010-10-01 2010-10-01 false Requesting information from the Healthcare... SERVICES GENERAL ADMINISTRATION HEALTHCARE INTEGRITY AND PROTECTION DATA BANK FOR FINAL ADVERSE INFORMATION ON HEALTH CARE PROVIDERS, SUPPLIERS AND PRACTITIONERS Disclosure of Information by the Healthcare...
45 CFR 61.12 - Requesting information from the Healthcare Integrity and Protection Data Bank.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 45 Public Welfare 1 2012-10-01 2012-10-01 false Requesting information from the Healthcare... SERVICES GENERAL ADMINISTRATION HEALTHCARE INTEGRITY AND PROTECTION DATA BANK FOR FINAL ADVERSE INFORMATION ON HEALTH CARE PROVIDERS, SUPPLIERS AND PRACTITIONERS Disclosure of Information by the Healthcare...
45 CFR 61.12 - Requesting information from the Healthcare Integrity and Protection Data Bank.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 45 Public Welfare 1 2011-10-01 2011-10-01 false Requesting information from the Healthcare... SERVICES GENERAL ADMINISTRATION HEALTHCARE INTEGRITY AND PROTECTION DATA BANK FOR FINAL ADVERSE INFORMATION ON HEALTH CARE PROVIDERS, SUPPLIERS AND PRACTITIONERS Disclosure of Information by the Healthcare...
48 CFR 52.215-14 - Integrity of Unit Prices.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Integrity of Unit Prices. 52.215-14 Section 52.215-14 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION... supplies shall distribute costs within contracts on a basis that ensures that unit prices are in proportion...
28 CFR 20.37 - Responsibility for accuracy, completeness, currency, and integrity.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Responsibility for accuracy, completeness, currency, and integrity. 20.37 Section 20.37 Judicial Administration DEPARTMENT OF JUSTICE CRIMINAL JUSTICE INFORMATION SYSTEMS Federal Systems and Exchange of Criminal History Record Information § 20.37 Responsibility...
48 CFR 3016.170 - Contracts with Lead System Integrators.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 48 Federal Acquisition Regulations System 7 2012-10-01 2012-10-01 false Contracts with Lead System... Selecting Contract Types 3016.170 Contracts with Lead System Integrators. The contracting officer should... consulted to determine the appropriate contract type and fee structure for use in varied contracts with lead...
48 CFR 3016.170 - Contracts with Lead System Integrators.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 48 Federal Acquisition Regulations System 7 2014-10-01 2014-10-01 false Contracts with Lead System... Selecting Contract Types 3016.170 Contracts with Lead System Integrators. The contracting officer should... consulted to determine the appropriate contract type and fee structure for use in varied contracts with lead...
48 CFR 3016.170 - Contracts with Lead System Integrators.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 48 Federal Acquisition Regulations System 7 2011-10-01 2011-10-01 false Contracts with Lead System... Selecting Contract Types 3016.170 Contracts with Lead System Integrators. The contracting officer should... consulted to determine the appropriate contract type and fee structure for use in varied contracts with lead...
48 CFR 3016.170 - Contracts with Lead System Integrators.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Contracts with Lead System... Selecting Contract Types 3016.170 Contracts with Lead System Integrators. The contracting officer should... consulted to determine the appropriate contract type and fee structure for use in varied contracts with lead...
Code of Federal Regulations, 2014 CFR
2014-10-01
... 47 Telecommunication 4 2014-10-01 2014-10-01 false System technical integration requiring uniform election of must-carry or retransmission consent status. 76.1608 Section 76.1608 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE...
Code of Federal Regulations, 2011 CFR
2011-10-01
... 47 Telecommunication 4 2011-10-01 2011-10-01 false System technical integration requiring uniform election of must-carry or retransmission consent status. 76.1608 Section 76.1608 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE...
Code of Federal Regulations, 2013 CFR
2013-10-01
... 47 Telecommunication 4 2013-10-01 2013-10-01 false System technical integration requiring uniform election of must-carry or retransmission consent status. 76.1608 Section 76.1608 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE...
Code of Federal Regulations, 2012 CFR
2012-10-01
... 47 Telecommunication 4 2012-10-01 2012-10-01 false System technical integration requiring uniform election of must-carry or retransmission consent status. 76.1608 Section 76.1608 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE...
Code of Federal Regulations, 2010 CFR
2010-10-01
... 47 Telecommunication 4 2010-10-01 2010-10-01 false System technical integration requiring uniform election of must-carry or retransmission consent status. 76.1608 Section 76.1608 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE...
USDA-ARS?s Scientific Manuscript database
The Sterile Insect Technique (SIT) as an integral component to the area-wide integrated management of the false codling moth, Thaumatotibia leucotreta (Meyrick) (Lepidoptera: Tortricidae), was successfully implemented in the Western Cape region of South Africa and subsequently expanded to citrus are...
He, Chenglin; Chen, Jinxiang; Wu, Zhishen; Xie, Juan; Zu, Qiao; Lu, Yun
2015-05-01
Honeycomb plates can be applied in many fields, including furniture manufacturing, mechanical engineering, civil engineering, transportation and aerospace. In the present study, we discuss the simulated effect on the mechanical properties of bionic integrated honeycomb plates by investigating the compressive and shear failure modes and the mechanical properties of trabeculae reinforced by long or short fibers. The results indicate that the simulated effect represents approximately 80% and 70% of the compressive and shear strengths, respectively. Compared with existing bionic samples, the mass-specific strength was significantly improved. Therefore, this integrated honeycomb technology remains the most effective method for the trial manufacturing of bionic integrated honeycomb plates. The simulated effect of the compressive rigidity is approximately 85%. The short-fiber trabeculae have an advantage over the long-fiber trabeculae in terms of shear rigidity, which provides new evidence for the application of integrated bionic honeycomb plates. Copyright © 2015 Elsevier B.V. All rights reserved.
7 CFR 3300.37 - Testing of a mechanical refrigerating appliance.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 7 Agriculture 15 2010-01-01 2010-01-01 false Testing of a mechanical refrigerating appliance. 3300... SPECIAL EQUIPMENT Procedures for Separate Testing of Mechanical Refrigerating Appliances § 3300.37 Testing of a mechanical refrigerating appliance. For separate testing of a mechanical refrigerating appliance...
46 CFR 154.1205 - Mechanical ventilation system: Standards.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 46 Shipping 5 2010-10-01 2010-10-01 false Mechanical ventilation system: Standards. 154.1205... Equipment Cargo Area: Mechanical Ventilation System § 154.1205 Mechanical ventilation system: Standards. (a) Each exhaust type mechanical ventilation system required under § 154.1200 (a) must have ducts for...
46 CFR 113.35-15 - Mechanical engine order telegraph systems; application.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 46 Shipping 4 2010-10-01 2010-10-01 false Mechanical engine order telegraph systems; application...-15 Mechanical engine order telegraph systems; application. If a mechanical engine order telegraph... cables or other mechanical limitations must not prevent the efficient operation of the system. ...
14 CFR 121.563 - Reporting mechanical irregularities.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Reporting mechanical irregularities. 121.563 Section 121.563 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... mechanical irregularities. The pilot in command shall ensure that all mechanical irregularities occurring...
7 CFR 58.417 - Mechanical agitators.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 7 Agriculture 3 2010-01-01 2010-01-01 false Mechanical agitators. 58.417 Section 58.417 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards....417 Mechanical agitators. The mechanical agitators shall be of sanitary construction. The carriages...
49 CFR 236.809 - Signal, slotted mechanical.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 49 Transportation 4 2010-10-01 2010-10-01 false Signal, slotted mechanical. 236.809 Section 236.809 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD... § 236.809 Signal, slotted mechanical. A mechanically operated signal with an electromagnetic device...
49 CFR 236.376 - Mechanical locking.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 49 Transportation 4 2010-10-01 2010-10-01 false Mechanical locking. 236.376 Section 236.376 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION... and Tests § 236.376 Mechanical locking. Mechanical locking in interlocking machine shall be tested...
Plancher, Gaën; Guyard, Anne; Nicolas, Serge; Piolino, Pascale
2009-10-01
It is well known that the occurrence of false memories increases with aging, but the results remain inconsistent concerning Alzheimer's disease (AD). Moreover, the mechanisms underlying the production of false memories are still unclear. Using an experimental episodic memory test with material based on the names of famous people in a procedure derived from the DRM paradigm [Roediger, H. L., III, & McDermott, K. B. (1995). Creating false memories: Remembering words not presented in lists. Journal of Experimental Psychology: Learning, Memory & Cognition, 21, 803-814], we examined correct and false recall and recognition in 30 young adults, 40 healthy older adults, and 30 patients with AD. Moreover, we evaluated the relationships between false memory performance, correct episodic memory performance, and a set of neuropsychological assessments evaluating the semantic memory and executive functions. The results clearly indicated that correct recall and recognition performance decreased with the subjects' age, but it decreased even more with AD. In addition, semantically related false recalls and false recognitions increased with age but not with dementia. On the contrary, non-semantically related false recalls and false recognitions increased with AD. Finally, the regression analyses showed that executive functions mediated related false memories and episodic memory mediated related and unrelated false memories in aging. Moreover, executive functions predicted related and unrelated false memories in AD, and episodic and semantic memory predicted semantically related and unrelated false memories in AD. In conclusion, the results obtained are consistent with the current constructive models of memory suggesting that false memory creation depends on different cognitive functions and, consequently, that the impairments of these functions influence the production of false memories.
2008-12-01
NAVAL POSTGRADUATE SCHOOL MONTEREY, CALIFORNIA THESIS INTEGRATING MONETARY AND NON-MONETARY REENLISTMENT INCENTIVES UTILIZING THE...Monetary and Non- monetary Reenlistment Incentives Utilizing the Combinatorial Retention Auction Mechanism (CRAM) 6. AUTHOR(S) Brooke Zimmerman 5...iii Approved for public release; distribution is unlimited INTEGRATING MONETARY AND NON-MONETARY REENLISTMENT INCENTIVES UTILIZING THE
Integrating Iris and Signature Traits for Personal Authentication Using User-Specific Weighting
Viriri, Serestina; Tapamo, Jules R.
2012-01-01
Biometric systems based on uni-modal traits are characterized by noisy sensor data, restricted degrees of freedom, non-universality and are susceptible to spoof attacks. Multi-modal biometric systems seek to alleviate some of these drawbacks by providing multiple evidences of the same identity. In this paper, a user-score-based weighting technique for integrating the iris and signature traits is presented. This user-specific weighting technique has proved to be an efficient and effective fusion scheme which increases the authentication accuracy rate of multi-modal biometric systems. The weights are used to indicate the importance of matching scores output by each biometrics trait. The experimental results show that our biometric system based on the integration of iris and signature traits achieve a false rejection rate (FRR) of 0.08% and a false acceptance rate (FAR) of 0.01%. PMID:22666032
Research a Novel Integrated and Dynamic Multi-object Trade-Off Mechanism in Software Project
NASA Astrophysics Data System (ADS)
Jiang, Weijin; Xu, Yuhui
Aiming at practical requirements of present software project management and control, the paper presented to construct integrated multi-object trade-off model based on software project process management, so as to actualize integrated and dynamic trade-oil of the multi-object system of project. Based on analyzing basic principle of dynamic controlling and integrated multi-object trade-off system process, the paper integrated method of cybernetics and network technology, through monitoring on some critical reference points according to the control objects, emphatically discussed the integrated and dynamic multi- object trade-off model and corresponding rules and mechanism in order to realize integration of process management and trade-off of multi-object system.
NASA Technical Reports Server (NTRS)
Mayer, Richard J.; Blinn, Thomas M.; Mayer, Paula S. D.; Reddy, Uday; Ackley, Keith; Futrell, Mike
1991-01-01
The Framework Programmable Software Development Platform (FPP) is a project aimed at combining effective tool and data integration mechanisms with a model of the software development process in an intelligent integrated software development environment. Guided by this model, this system development framework will take advantage of an integrated operating environment to automate effectively the management of the software development process so that costly mistakes during the development phase can be eliminated.
49 CFR 236.339 - Mechanical locking, maintenance requirements.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 49 Transportation 4 2010-10-01 2010-10-01 false Mechanical locking, maintenance requirements. 236... Interlocking Rules and Instructions § 236.339 Mechanical locking, maintenance requirements. Locking and... prevented: (a) Mechanical machine—(1) Latch-operated locking. Raising lever latch block so that bottom...
14 CFR 125.323 - Reporting mechanical irregularities.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Reporting mechanical irregularities. 125.323 Section 125.323 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... § 125.323 Reporting mechanical irregularities. The pilot in command shall ensure that all mechanical...
14 CFR 27.691 - Autorotation control mechanism.
Code of Federal Regulations, 2013 CFR
2013-01-01
... AIRCRAFT AIRWORTHINESS STANDARDS: NORMAL CATEGORY ROTORCRAFT Design and Construction Control Systems § 27.691 Autorotation control mechanism. Each main rotor blade pitch control mechanism must allow rapid... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Autorotation control mechanism. 27.691...
14 CFR 29.691 - Autorotation control mechanism.
Code of Federal Regulations, 2013 CFR
2013-01-01
... AIRCRAFT AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY ROTORCRAFT Design and Construction Control Systems § 29.691 Autorotation control mechanism. Each main rotor blade pitch control mechanism must allow rapid... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Autorotation control mechanism. 29.691...
A Theory of False Cognitive Expectancies in Airline Pilots
NASA Astrophysics Data System (ADS)
Cortes, Antonio I.
The Theory of False Cognitive Expectancies was developed by studying high reliability flight operations. Airline pilots depend extensively on cognitive expectancies to perceive, understand, and predict actions and events. Out of 1,363 incident reports submitted by airline pilots to the National Aeronautics and Space Administration Aviation Safety Reporting System over a year's time, 110 reports were found to contain evidence of 127 false cognitive expectancies in pilots. A comprehensive taxonomy was developed with six categories of interest. The dataset of 127 false expectancies was used to initially code tentative taxon values for each category. Intermediate coding through constant comparative analysis completed the taxonomy. The taxonomy was used for the advanced coding of chronological context-dependent visualizations of expectancy factors, known as strands, which depict the major factors in the creation and propagation of each expectancy. Strands were mapped into common networks to detect highly represented expectancy processes. Theoretical integration established 11 sources of false expectancies, the most common expectancy errors, and those conspicuous factors worthy of future study. The most prevalent source of false cognitive expectancies within the dataset was determined to be unconscious individual modeling based on past events. Integrative analyses also revealed relationships between expectancies and flight deck automation, unresolved discrepancies, and levels of situation awareness. Particularly noteworthy were the findings that false expectancies can combine in three possible permutations to diminish situation awareness and examples of how false expectancies can be unwittingly transmitted from one person to another. The theory resulting from this research can enhance the error coding process used during aircraft line oriented safety audits, lays the foundation for developing expectancy management training programs, and will allow researchers to proffer hypotheses for human testing using flight simulators.
Project Integration Architecture: Distributed Lock Management, Deadlock Detection, and Set Iteration
NASA Technical Reports Server (NTRS)
Jones, William Henry
2005-01-01
The migration of the Project Integration Architecture (PIA) to the distributed object environment of the Common Object Request Broker Architecture (CORBA) brings with it the nearly unavoidable requirements of multiaccessor, asynchronous operations. In order to maintain the integrity of data structures in such an environment, it is necessary to provide a locking mechanism capable of protecting the complex operations typical of the PIA architecture. This paper reports on the implementation of a locking mechanism to treat that need. Additionally, the ancillary features necessary to make the distributed lock mechanism work are discussed.
Fandakova, Yana; Shing, Yee Lee; Lindenberger, Ulman
2013-10-01
Based on a 2-component framework of episodic memory development across the lifespan (Shing & Lindenberger, 2011), we examined the contribution of memory-related binding and monitoring processes to false memory susceptibility in childhood and old age. We administered a repeated continuous recognition task to children (N = 20, 10-12 years), younger adults (N = 20, 20-27 years), and older adults (N = 21, 68-76 years). Participants saw the same set of unrelated word pairs in 3 consecutive runs and their task was to identify pair reoccurrences within runs. Across runs, correct detection of repeated pairs decreased in children only, whereas false recognition of lure pairs showed a greater increase in older adults than in children or younger adults. False recognition of rearranged pairs decreased across runs for all participants. This decrease was most pronounced in children, in particular for high-confidence memory errors. We conclude that memory binding mechanisms are sufficiently developed in children to facilitate memory monitoring and reduce false memory for associative information. In contrast, older adults show senescent impairments in both binding and monitoring mechanisms that both contribute to elevated illusory recollections in old age. We conclude that binding and monitoring processes during memory performance follow different developmental trajectories from childhood to old age.
A Screening Mechanism Differentiating True from False Pain during Empathy.
Sun, Ya-Bin; Lin, Xiao-Xiao; Ye, Wen; Wang, Ning; Wang, Jin-Yan; Luo, Fei
2017-09-13
Empathizing with another's suffering is important in social interactions. Empathic behavior is selectively elicited from genuine, meaningful pain but not from fake, meaningless scenarios. However, the brain's screening mechanism of false information from meaningful events and the time course for the screening process remains unclear. Using EEG combined with principle components analysis (PCA) techniques, here we compared temporal neurodynamics between the observation of pain and no-pain pictures as well as between true (painful expressions and needle-penetrated arms) and false (needle-penetrated faces with neutral expressions) pain pictures. The results revealed that pain vs. no-pain information is differentiated in the very early ERP components, i.e., the N1/P1 for the face and arm pictures categories and the VPP/N170 for the facial expression category while the mid-latency ERP components, N2 and P3, played key roles in differentiating true from false situations. The complex of N2 and P3 components may serve as a screening mechanism through which observers allocate their attentions to more important or relevant events and screen out false environmental information. This is the first study to describe and provide a time course of the screening process during pain empathy. These findings shed new light on the understanding of empathic processing.
Biblical Worldview: The Christian Higher Education Foundation for Learning
ERIC Educational Resources Information Center
Esqueda, Octavio Javier
2014-01-01
The integration of faith and learning is regarded to be a primary distinctive of Christian higher education, yet this terminology conveys a false dichotomy. The frequent call for integration suggests that the Christian faith and learning belong to different areas of knowledge and practice; consequently, there is a need for bringing the two realms…
Code of Federal Regulations, 2013 CFR
2013-07-01
... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false Where may Executive agencies find additional information on Integrated Workplace concepts? 102-79.111 Section 102-79.111 Public Contracts and Property Management Federal Property Management Regulations System (Continued) FEDERAL...
Code of Federal Regulations, 2011 CFR
2011-01-01
... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false Where may Executive agencies find additional information on Integrated Workplace concepts? 102-79.111 Section 102-79.111 Public Contracts and Property Management Federal Property Management Regulations System (Continued) FEDERAL...
Code of Federal Regulations, 2014 CFR
2014-01-01
... 41 Public Contracts and Property Management 3 2014-01-01 2014-01-01 false Where may Executive agencies find additional information on Integrated Workplace concepts? 102-79.111 Section 102-79.111 Public Contracts and Property Management Federal Property Management Regulations System (Continued) FEDERAL...
Code of Federal Regulations, 2012 CFR
2012-01-01
... 41 Public Contracts and Property Management 3 2012-01-01 2012-01-01 false Where may Executive agencies find additional information on Integrated Workplace concepts? 102-79.111 Section 102-79.111 Public Contracts and Property Management Federal Property Management Regulations System (Continued) FEDERAL...
46 CFR 154.419 - Design vapor pressure.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 46 Shipping 5 2010-10-01 2010-10-01 false Design vapor pressure. 154.419 Section 154.419 Shipping... FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Design, Construction and Equipment Integral Tanks § 154.419 Design vapor pressure. The Po of an integral tank must not exceed 24.5 kPa gauge (3.55...
Code of Federal Regulations, 2011 CFR
2011-10-01
... 45 Public Welfare 1 2011-10-01 2011-10-01 false How to dispute the accuracy of Healthcare... HUMAN SERVICES GENERAL ADMINISTRATION HEALTHCARE INTEGRITY AND PROTECTION DATA BANK FOR FINAL ADVERSE INFORMATION ON HEALTH CARE PROVIDERS, SUPPLIERS AND PRACTITIONERS Disclosure of Information by the Healthcare...
Code of Federal Regulations, 2010 CFR
2010-10-01
... 45 Public Welfare 1 2010-10-01 2010-10-01 false How to dispute the accuracy of Healthcare... HUMAN SERVICES GENERAL ADMINISTRATION HEALTHCARE INTEGRITY AND PROTECTION DATA BANK FOR FINAL ADVERSE INFORMATION ON HEALTH CARE PROVIDERS, SUPPLIERS AND PRACTITIONERS Disclosure of Information by the Healthcare...
Code of Federal Regulations, 2012 CFR
2012-10-01
... 45 Public Welfare 1 2012-10-01 2012-10-01 false How to dispute the accuracy of Healthcare... HUMAN SERVICES GENERAL ADMINISTRATION HEALTHCARE INTEGRITY AND PROTECTION DATA BANK FOR FINAL ADVERSE INFORMATION ON HEALTH CARE PROVIDERS, SUPPLIERS AND PRACTITIONERS Disclosure of Information by the Healthcare...
29 CFR 784.122 - Operations performed as an integrated part of fishing.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 29 Labor 3 2011-07-01 2011-07-01 false Operations performed as an integrated part of fishing. 784... PROVISIONS OF THE FAIR LABOR STANDARDS ACT APPLICABLE TO FISHING AND OPERATIONS ON AQUATIC PRODUCTS Exemptions Provisions Relating to Fishing and Aquatic Products General Character and Scope of the Section 13...
29 CFR 784.122 - Operations performed as an integrated part of fishing.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 29 Labor 3 2013-07-01 2013-07-01 false Operations performed as an integrated part of fishing. 784... PROVISIONS OF THE FAIR LABOR STANDARDS ACT APPLICABLE TO FISHING AND OPERATIONS ON AQUATIC PRODUCTS Exemptions Provisions Relating to Fishing and Aquatic Products General Character and Scope of the Section 13...
29 CFR 784.122 - Operations performed as an integrated part of fishing.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 29 Labor 3 2012-07-01 2012-07-01 false Operations performed as an integrated part of fishing. 784... PROVISIONS OF THE FAIR LABOR STANDARDS ACT APPLICABLE TO FISHING AND OPERATIONS ON AQUATIC PRODUCTS Exemptions Provisions Relating to Fishing and Aquatic Products General Character and Scope of the Section 13...
29 CFR 784.122 - Operations performed as an integrated part of fishing.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 29 Labor 3 2010-07-01 2010-07-01 false Operations performed as an integrated part of fishing. 784... PROVISIONS OF THE FAIR LABOR STANDARDS ACT APPLICABLE TO FISHING AND OPERATIONS ON AQUATIC PRODUCTS Exemptions Provisions Relating to Fishing and Aquatic Products General Character and Scope of the Section 13...
29 CFR 784.122 - Operations performed as an integrated part of fishing.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 29 Labor 3 2014-07-01 2014-07-01 false Operations performed as an integrated part of fishing. 784... PROVISIONS OF THE FAIR LABOR STANDARDS ACT APPLICABLE TO FISHING AND OPERATIONS ON AQUATIC PRODUCTS Exemptions Provisions Relating to Fishing and Aquatic Products General Character and Scope of the Section 13...
49 CFR 571.303 - Standard No. 303; Fuel system integrity of compressed natural gas vehicles.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 49 Transportation 6 2013-10-01 2013-10-01 false Standard No. 303; Fuel system integrity of compressed natural gas vehicles. 571.303 Section 571.303 Transportation Other Regulations Relating to Transportation (Continued) NATIONAL HIGHWAY TRAFFIC SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR VEHICLE SAFETY STANDARDS Federal...
ERIC Educational Resources Information Center
Ford, Julie Dyke
2012-01-01
This program profile describes a new approach towards integrating communication within Mechanical Engineering curricula. The author, who holds a joint appointment between Technical Communication and Mechanical Engineering at New Mexico Institute of Mining and Technology, has been collaborating with Mechanical Engineering colleagues to establish a…
Design, Fabrication, Characterization and Modeling of Integrated Functional Materials
2011-10-01
the integration of multiple functionalities with desirable properties (thermal, electrical, magnetic, mechanical , optical, etc.), the connection to...mediated magnetic interactions in the nanocomposites. Our systematic studies on the underlying mechanism of magnetic interactions between graphene...or 3- nanocrystalline phases have been seen simultaneously within an amorphous matrix. The mechanism for induced magnetic anisotropy in these alloys
Outside-in control -Does plant cell wall integrity regulate cell cycle progression?
Gigli-Bisceglia, Nora; Hamann, Thorsten
2018-04-13
During recent years it has become accepted that plant cell walls are not inert objects surrounding all plant cells but are instead highly dynamic, plastic structures. They are involved in a large number of cell biological processes and contribute actively to plant growth, development and interaction with environment. Therefore, it is not surprising that cellular processes can control plant cell wall integrity while, simultaneously, cell wall integrity can influence cellular processes. In yeast and animal cells such a bi-directional relationship also exists between the yeast/animal extra-cellular matrices and the cell cycle. In yeast, the cell wall integrity maintenance mechanism and a dedicated plasmamembrane integrity checkpoint are mediating this relationship. Recent research has yielded insights into the mechanism controlling plant cell wall metabolism during cytokinesis. However, knowledge regarding putative regulatory pathways controlling adaptive modifications in plant cell cycle activity in response to changes in the state of the plant cell wall are not yet identified. In this review, we summarize similarities and differences in regulatory mechanisms coordinating extra cellular matrices and cell cycle activity in animal and yeast cells, discuss the available evidence supporting the existence of such a mechanism in plants and suggest that the plant cell wall integrity maintenance mechanism might also control cell cycle activity in plant cells. This article is protected by copyright. All rights reserved.
Mechanical Model of Traditional Thai Massage for Integrated Healthcare.
Rattanaphan, Salinee; Srichandr, Panya
2015-01-01
In this study, a mechanical model was developed, aiming to provide standardized and programmable traditional Thai massage (TTM) therapy to patients. The TTM was modeled and integrated into a mechanical hand (MH) system, and a prototype massage chair was built and tested for user satisfaction. Three fundamental principles of Thai massage were integrated: pull, press, and pin. Based on these principles, the mechanics of Thai massage was studied and a mathematical model was developed to describe the dynamics and conditions for the design and prototyping of an MH. On average, it was found that users were satisfied with the treatment and felt that the treatment was similar to that performed by human hands. According to the interview results, users indicated that they were likely to utilize the MH as an alternative to traditional massage. Therefore, integrated TTM with an MH may help healthcare providers deliver standardized, programmable massage therapy to patients as opposed to variable, inconsistent human massage.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 49 Transportation 4 2013-10-01 2013-10-01 false Electromechanical interlocking machine; locking between electrical and mechanical levers. 236.340 Section 236.340 Transportation Other Regulations... Electromechanical interlocking machine; locking between electrical and mechanical levers. In electro-mechanical...
Code of Federal Regulations, 2014 CFR
2014-10-01
... 49 Transportation 4 2014-10-01 2014-10-01 false Electromechanical interlocking machine; locking between electrical and mechanical levers. 236.340 Section 236.340 Transportation Other Regulations... Electromechanical interlocking machine; locking between electrical and mechanical levers. In electro-mechanical...
Code of Federal Regulations, 2012 CFR
2012-10-01
... 49 Transportation 4 2012-10-01 2012-10-01 false Electromechanical interlocking machine; locking between electrical and mechanical levers. 236.340 Section 236.340 Transportation Other Regulations... Electromechanical interlocking machine; locking between electrical and mechanical levers. In electro-mechanical...
Code of Federal Regulations, 2011 CFR
2011-10-01
... 49 Transportation 4 2011-10-01 2011-10-01 false Electromechanical interlocking machine; locking between electrical and mechanical levers. 236.340 Section 236.340 Transportation Other Regulations... Electromechanical interlocking machine; locking between electrical and mechanical levers. In electro-mechanical...
16 CFR 703.3 - Mechanism organization.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Mechanism organization. 703.3 Section 703.3 Commercial Practices FEDERAL TRADE COMMISSION RULES, REGULATIONS, STATEMENTS AND INTERPRETATIONS UNDER THE... § 703.3 Mechanism organization. (a) The Mechanism shall be funded and competently staffed at a level...
49 CFR 236.809 - Signal, slotted mechanical.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 49 Transportation 4 2011-10-01 2011-10-01 false Signal, slotted mechanical. 236.809 Section 236..., INSPECTION, MAINTENANCE, AND REPAIR OF SIGNAL AND TRAIN CONTROL SYSTEMS, DEVICES, AND APPLIANCES Definitions § 236.809 Signal, slotted mechanical. A mechanically operated signal with an electromagnetic device...
14 CFR 135.65 - Reporting mechanical irregularities.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Reporting mechanical irregularities. 135.65... Operations § 135.65 Reporting mechanical irregularities. (a) Each certificate holder shall provide an aircraft maintenance log to be carried on board each aircraft for recording or deferring mechanical...
14 CFR 135.417 - Mechanical interruption summary report.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Mechanical interruption summary report. 135... Maintenance, Preventive Maintenance, and Alterations § 135.417 Mechanical interruption summary report. Each... unscheduled stop or diversion from a route, caused by known or suspected mechanical difficulties or...
21 CFR 876.5280 - Implanted mechanical/hydraulic urinary continence device.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Implanted mechanical/hydraulic urinary continence....5280 Implanted mechanical/hydraulic urinary continence device. (a) Identification. An implanted mechanical/hydraulic urinary continence device is a device used to treat urinary incontinence by the...
30 CFR 75.382 - Mechanical escape facilities.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Mechanical escape facilities. 75.382 Section 75... HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Ventilation § 75.382 Mechanical escape facilities. (a) Mechanical escape facilities shall be provided with overspeed, overwind, and automatic stop...
21 CFR 876.5280 - Implanted mechanical/hydraulic urinary continence device.
Code of Federal Regulations, 2014 CFR
2014-04-01
... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Implanted mechanical/hydraulic urinary continence....5280 Implanted mechanical/hydraulic urinary continence device. (a) Identification. An implanted mechanical/hydraulic urinary continence device is a device used to treat urinary incontinence by the...
21 CFR 876.5280 - Implanted mechanical/hydraulic urinary continence device.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Implanted mechanical/hydraulic urinary continence....5280 Implanted mechanical/hydraulic urinary continence device. (a) Identification. An implanted mechanical/hydraulic urinary continence device is a device used to treat urinary incontinence by the...
21 CFR 876.5280 - Implanted mechanical/hydraulic urinary continence device.
Code of Federal Regulations, 2012 CFR
2012-04-01
... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Implanted mechanical/hydraulic urinary continence....5280 Implanted mechanical/hydraulic urinary continence device. (a) Identification. An implanted mechanical/hydraulic urinary continence device is a device used to treat urinary incontinence by the...
21 CFR 876.5280 - Implanted mechanical/hydraulic urinary continence device.
Code of Federal Regulations, 2013 CFR
2013-04-01
... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Implanted mechanical/hydraulic urinary continence....5280 Implanted mechanical/hydraulic urinary continence device. (a) Identification. An implanted mechanical/hydraulic urinary continence device is a device used to treat urinary incontinence by the...
29 CFR 1910.219 - Mechanical power-transmission apparatus.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 29 Labor 5 2011-07-01 2011-07-01 false Mechanical power-transmission apparatus. 1910.219 Section... Mechanical power-transmission apparatus. (a) General requirements. (1) This section covers all types and... apparatus located in basements. All mechanical power transmission apparatus located in basements, towers...
29 CFR 1910.219 - Mechanical power-transmission apparatus.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 29 Labor 5 2010-07-01 2010-07-01 false Mechanical power-transmission apparatus. 1910.219 Section... Mechanical power-transmission apparatus. (a) General requirements. (1) This section covers all types and... apparatus located in basements. All mechanical power transmission apparatus located in basements, towers...
49 CFR 236.809 - Signal, slotted mechanical.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 49 Transportation 4 2012-10-01 2012-10-01 false Signal, slotted mechanical. 236.809 Section 236..., INSPECTION, MAINTENANCE, AND REPAIR OF SIGNAL AND TRAIN CONTROL SYSTEMS, DEVICES, AND APPLIANCES Definitions § 236.809 Signal, slotted mechanical. A mechanically operated signal with an electromagnetic device...
49 CFR 236.809 - Signal, slotted mechanical.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 49 Transportation 4 2013-10-01 2013-10-01 false Signal, slotted mechanical. 236.809 Section 236..., INSPECTION, MAINTENANCE, AND REPAIR OF SIGNAL AND TRAIN CONTROL SYSTEMS, DEVICES, AND APPLIANCES Definitions § 236.809 Signal, slotted mechanical. A mechanically operated signal with an electromagnetic device...
49 CFR 236.809 - Signal, slotted mechanical.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 49 Transportation 4 2014-10-01 2014-10-01 false Signal, slotted mechanical. 236.809 Section 236..., INSPECTION, MAINTENANCE, AND REPAIR OF SIGNAL AND TRAIN CONTROL SYSTEMS, DEVICES, AND APPLIANCES Definitions § 236.809 Signal, slotted mechanical. A mechanically operated signal with an electromagnetic device...
Using an architectural approach to integrate heterogeneous, distributed software components
NASA Technical Reports Server (NTRS)
Callahan, John R.; Purtilo, James M.
1995-01-01
Many computer programs cannot be easily integrated because their components are distributed and heterogeneous, i.e., they are implemented in diverse programming languages, use different data representation formats, or their runtime environments are incompatible. In many cases, programs are integrated by modifying their components or interposing mechanisms that handle communication and conversion tasks. For example, remote procedure call (RPC) helps integrate heterogeneous, distributed programs. When configuring such programs, however, mechanisms like RPC must be used explicitly by software developers in order to integrate collections of diverse components. Each collection may require a unique integration solution. This paper describes improvements to the concepts of software packaging and some of our experiences in constructing complex software systems from a wide variety of components in different execution environments. Software packaging is a process that automatically determines how to integrate a diverse collection of computer programs based on the types of components involved and the capabilities of available translators and adapters in an environment. Software packaging provides a context that relates such mechanisms to software integration processes and reduces the cost of configuring applications whose components are distributed or implemented in different programming languages. Our software packaging tool subsumes traditional integration tools like UNIX make by providing a rule-based approach to software integration that is independent of execution environments.
Security attack detection algorithm for electric power gis system based on mobile application
NASA Astrophysics Data System (ADS)
Zhou, Chao; Feng, Renjun; Wang, Liming; Huang, Wei; Guo, Yajuan
2017-05-01
Electric power GIS is one of the key information technologies to satisfy the power grid construction in China, and widely used in power grid construction planning, weather, and power distribution management. The introduction of electric power GIS based on mobile applications is an effective extension of the geographic information system that has been widely used in the electric power industry. It provides reliable, cheap and sustainable power service for the country. The accurate state estimation is the important conditions to maintain the normal operation of the electric power GIS. Recent research has shown that attackers can inject the complex false data into the power system. The injection attack of this new type of false data (load integrity attack LIA) can successfully bypass the routine detection to achieve the purpose of attack, so that the control center will make a series of wrong decision. Eventually, leading to uneven distribution of power in the grid. In order to ensure the safety of the electric power GIS system based on mobile application, it is very important to analyze the attack mechanism and propose a new type of attack, and to study the corresponding detection method and prevention strategy in the environment of electric power GIS system based on mobile application.
Predicting disease-related proteins based on clique backbone in protein-protein interaction network.
Yang, Lei; Zhao, Xudong; Tang, Xianglong
2014-01-01
Network biology integrates different kinds of data, including physical or functional networks and disease gene sets, to interpret human disease. A clique (maximal complete subgraph) in a protein-protein interaction network is a topological module and possesses inherently biological significance. A disease-related clique possibly associates with complex diseases. Fully identifying disease components in a clique is conductive to uncovering disease mechanisms. This paper proposes an approach of predicting disease proteins based on cliques in a protein-protein interaction network. To tolerate false positive and negative interactions in protein networks, extending cliques and scoring predicted disease proteins with gene ontology terms are introduced to the clique-based method. Precisions of predicted disease proteins are verified by disease phenotypes and steadily keep to more than 95%. The predicted disease proteins associated with cliques can partly complement mapping between genotype and phenotype, and provide clues for understanding the pathogenesis of serious diseases.
Zhang, Min-Jian
2017-07-01
Researches on the mechanisms underlying the therapeutic effects of the disease-syndrome combination approach in integrated traditional Chinese and Western medicine are becoming a hot spot in andrology, but many recent studies of this kind have failed to explain the connotation of integrated traditional Chinese and Western medicine in andrology. Related existing problems include repeated researches into the same indexes of action mechanisms of different therapeutic principles of traditional Chinese medicine (TCM), Chinese herbal compound and special prescriptions, studies focusing on individual diseases but ignoring symptoms, immature syndrome models for studies of mechanisms, and too much attention to uncertain or immature target mechanisms. The stress should be placed on the action mechanisms of Chinese herbal compound and special prescriptions on male diseases and, what is more important, on the clarification of the essential principles of differentiation and treatment of TCM syndromes. In the recent years, proteomics, genomics, transcriptomics and metabolomics have shed some light upon researches into the mechanisms underlying the therapeutic effects of the disease-syndrome combination approach in integrated traditional Chinese and Western medicine in andrology. An insight into the TCM syndrome, a macroscopic inductive analysis, and a comprehension of such microcosmic aspects as the gene, protein, metabolism and metagenome may contribute to some breakthroughs and new ideas in the studies of disease-syndrome combination in integrated traditional Chinese and Western medicine in andrology.
49 CFR 236.337 - Locking faces of mechanical locking; fit.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 49 Transportation 4 2011-10-01 2011-10-01 false Locking faces of mechanical locking; fit. 236.337... Rules and Instructions § 236.337 Locking faces of mechanical locking; fit. Locking faces shall fit... face. ...
49 CFR 236.337 - Locking faces of mechanical locking; fit.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 49 Transportation 4 2012-10-01 2012-10-01 false Locking faces of mechanical locking; fit. 236.337... Rules and Instructions § 236.337 Locking faces of mechanical locking; fit. Locking faces shall fit... face. ...
49 CFR 236.337 - Locking faces of mechanical locking; fit.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 49 Transportation 4 2014-10-01 2014-10-01 false Locking faces of mechanical locking; fit. 236.337... Rules and Instructions § 236.337 Locking faces of mechanical locking; fit. Locking faces shall fit... face. ...
49 CFR 236.337 - Locking faces of mechanical locking; fit.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 49 Transportation 4 2013-10-01 2013-10-01 false Locking faces of mechanical locking; fit. 236.337... Rules and Instructions § 236.337 Locking faces of mechanical locking; fit. Locking faces shall fit... face. ...
Knee Joint Kinematics and Kinetics During a Lateral False-Step Maneuver
Golden, Grace M.; Pavol, Michael J.; Hoffman, Mark A.
2009-01-01
Abstract Context: Cutting maneuvers have been implicated as a mechanism of noncontact anterior cruciate ligament (ACL) injuries in collegiate female basketball players. Objective: To investigate knee kinematics and kinetics during running when the width of a single step, relative to the path of travel, was manipulated, a lateral false-step maneuver. Design: Crossover design. Setting: University biomechanics laboratory. Patients or Other Participants: Thirteen female collegiate basketball athletes (age = 19.7 ± 1.1 years, height = 172.3 ± 8.3 cm, mass = 71.8 ± 8.7 kg). Intervention(s): Three conditions: normal straight-ahead running, lateral false step of width 20% of body height, and lateral false step of width 35% of body height. Main Outcome Measure(s): Peak angles and internal moments for knee flexion, extension, abduction, adduction, internal rotation, and external rotation. Results: Differences were noted among conditions in peak knee angles (flexion [P < .01], extension [P = .02], abduction [P < .01], and internal rotation [P < .01]) and peak internal knee moments (abduction [P < .01], adduction [P < .01], and internal rotation [P = .03]). The lateral false step of width 35% of body height was associated with larger peak flexion, abduction, and internal rotation angles and larger peak abduction, adduction, and internal rotation moments than normal running. Peak flexion and internal rotation angles were also larger for the lateral false step of width 20% of body height than for normal running, whereas peak extension angle was smaller. Peak internal rotation angle increased progressively with increasing step width. Conclusions: Performing a lateral false-step maneuver resulted in changes in knee kinematics and kinetics compared with normal running. The differences observed for lateral false steps were consistent with proposed mechanisms of ACL loading, suggesting that lateral false steps represent a hitherto neglected mechanism of noncontact ACL injury. PMID:19771289
46 CFR 54.30-10 - Method of performing mechanical stress relief.
Code of Federal Regulations, 2011 CFR
2011-10-01
... PRESSURE VESSELS Mechanical Stress Relief § 54.30-10 Method of performing mechanical stress relief. (a) The mechanical stress relief shall be carried out in accordance with the following stipulations using water as... 46 Shipping 2 2011-10-01 2011-10-01 false Method of performing mechanical stress relief. 54.30-10...
46 CFR 54.30-10 - Method of performing mechanical stress relief.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 46 Shipping 2 2010-10-01 2010-10-01 false Method of performing mechanical stress relief. 54.30-10... PRESSURE VESSELS Mechanical Stress Relief § 54.30-10 Method of performing mechanical stress relief. (a) The mechanical stress relief shall be carried out in accordance with the following stipulations using water as...
46 CFR 54.30-10 - Method of performing mechanical stress relief.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 46 Shipping 2 2014-10-01 2014-10-01 false Method of performing mechanical stress relief. 54.30-10... PRESSURE VESSELS Mechanical Stress Relief § 54.30-10 Method of performing mechanical stress relief. (a) The mechanical stress relief shall be carried out in accordance with the following stipulations using water as...
46 CFR 54.30-10 - Method of performing mechanical stress relief.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 46 Shipping 2 2013-10-01 2013-10-01 false Method of performing mechanical stress relief. 54.30-10... PRESSURE VESSELS Mechanical Stress Relief § 54.30-10 Method of performing mechanical stress relief. (a) The mechanical stress relief shall be carried out in accordance with the following stipulations using water as...
46 CFR 54.30-10 - Method of performing mechanical stress relief.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 46 Shipping 2 2012-10-01 2012-10-01 false Method of performing mechanical stress relief. 54.30-10... PRESSURE VESSELS Mechanical Stress Relief § 54.30-10 Method of performing mechanical stress relief. (a) The mechanical stress relief shall be carried out in accordance with the following stipulations using water as...
Identifying cooperative transcriptional regulations using protein–protein interactions
Nagamine, Nobuyoshi; Kawada, Yuji; Sakakibara, Yasubumi
2005-01-01
Cooperative transcriptional activations among multiple transcription factors (TFs) are important to understand the mechanisms of complex transcriptional regulations in eukaryotes. Previous studies have attempted to find cooperative TFs based on gene expression data with gene expression profiles as a measure of similarity of gene regulations. In this paper, we use protein–protein interaction data to infer synergistic binding of cooperative TFs. Our fundamental idea is based on the assumption that genes contributing to a similar biological process are regulated under the same control mechanism. First, the protein–protein interaction networks are used to calculate the similarity of biological processes among genes. Second, we integrate this similarity and the chromatin immuno-precipitation data to identify cooperative TFs. Our computational experiments in yeast show that predictions made by our method have successfully identified eight pairs of cooperative TFs that have literature evidences but could not be identified by the previous method. Further, 12 new possible pairs have been inferred and we have examined the biological relevances for them. However, since a typical problem using protein–protein interaction data is that many false-positive data are contained, we propose a method combining various biological data to increase the prediction accuracy. PMID:16126847
40 CFR 68.73 - Mechanical integrity.
Code of Federal Regulations, 2010 CFR
2010-07-01
...) CHEMICAL ACCIDENT PREVENTION PROVISIONS Program 3 Prevention Program § 68.73 Mechanical integrity. (a... accepted good engineering practices. (3) The frequency of inspections and tests of process equipment shall be consistent with applicable manufacturers' recommendations and good engineering practices, and more...
40 CFR 68.73 - Mechanical integrity.
Code of Federal Regulations, 2012 CFR
2012-07-01
...) CHEMICAL ACCIDENT PREVENTION PROVISIONS Program 3 Prevention Program § 68.73 Mechanical integrity. (a... accepted good engineering practices. (3) The frequency of inspections and tests of process equipment shall be consistent with applicable manufacturers' recommendations and good engineering practices, and more...
40 CFR 68.73 - Mechanical integrity.
Code of Federal Regulations, 2013 CFR
2013-07-01
...) CHEMICAL ACCIDENT PREVENTION PROVISIONS Program 3 Prevention Program § 68.73 Mechanical integrity. (a... accepted good engineering practices. (3) The frequency of inspections and tests of process equipment shall be consistent with applicable manufacturers' recommendations and good engineering practices, and more...
40 CFR 68.73 - Mechanical integrity.
Code of Federal Regulations, 2011 CFR
2011-07-01
...) CHEMICAL ACCIDENT PREVENTION PROVISIONS Program 3 Prevention Program § 68.73 Mechanical integrity. (a... accepted good engineering practices. (3) The frequency of inspections and tests of process equipment shall be consistent with applicable manufacturers' recommendations and good engineering practices, and more...
MECHANICAL INTEGRITY TESTING AND TRAINING FACILITY
Underground injection control regulations of the U.S. Environmental Protection Agency require that all injection wells demonstrate mechanical integrity, which is defined as no significant leak in the casing, tubing or packer, and no significant fluid movement into an underground ...
DETECTING WATER FLOW BEHIND PIPE IN INJECTION WELLS
Regulations of the Environmental Protection Agency require that an injection well exhibit both internal and external mechanical integrity. The external mechanical integrity consideration is that there is no significant fluid movement into an underground source of drinking water ...
Acute effects of triazolam on false recognition.
Mintzer, M Z; Griffiths, R R
2000-12-01
Neuropsychological, neuroimaging, and electrophysiological techniques have been applied to the study of false recognition; however, psychopharmacological techniques have not been applied. Benzodiazepine sedative/anxiolytic drugs produce memory deficits similar to those observed in organic amnesia and may be useful tools for studying normal and abnormal memory mechanisms. The present double-blind, placebo-controlled repeated measures study examined the acute effects of orally administered triazolam (Halcion; 0.125 and 0.25 mg/70 kg), a benzodiazepine hypnotic, on performance in the Deese (1959)/Roediger-McDermott (1995) false recognition paradigm in 24 healthy volunteers. Paralleling previous demonstrations in amnesic patients, triazolam produced significant dose-related reductions in false recognition rates to nonstudied words associatively related to studied words, suggesting that false recognition relies on normal memory mechanisms impaired in benzodiazepine-induced amnesia. The results also suggested that relative to placebo, triazolam reduced participants' reliance on memory for item-specific versus list-common semantic information and reduced participants' use of remember versus know responses.
Machado, Sergio; Cunha, Marlo; Velasques, Bruna; Minc, Daniel; Teixeira, Silmar; Domingues, Clayton A; Silva, Julio G; Bastos, Victor H; Budde, Henning; Cagy, Mauricio; Basile, Luis; Piedade, Roberto; Ribeiro, Pedro
2010-10-01
Sensorimotor integration is defined as the capability of the central nervous system to integrate different sources of stimuli, and parallelly, to transform such inputs in motor actions. To review the basic principles of sensorimotor integration, such as, its neural bases and its elementary mechanisms involved in specific goal-directed tasks performed by healthy subjects, and the abnormalities reported in the most common movement disorders, such as, Parkinson' disease, dystonia and stroke, like the cortical reorganization-related mechanisms. Whether these disorders are associated with an abnormal peripheral sensory input or defective central processing is still unclear, but most of the data support a central mechanism. We found that the sensorimotor integration process plays a potential role in elementary mechanisms involved in specific goal-directed tasks performed by healthy subjects and in occurrence of abnormalities in most common movement disorders and, moreover, play a potential role on the acquisition of abilities that have as critical factor the coupling of different sensory data which will constitute the basis of elaboration of motor outputs consciously goal-directed.
47 CFR 1.357 - Mechanical reproductions as evidence.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 47 Telecommunication 1 2011-10-01 2011-10-01 false Mechanical reproductions as evidence. 1.357... Proceedings Evidence § 1.357 Mechanical reproductions as evidence. Unless offered for the sole purpose of attempting to prove or demonstrate sound effect, mechanical or physical reproductions of sound waves shall...
7 CFR 801.5 - Tolerance for diverter-type mechanical samplers.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 7 Agriculture 7 2010-01-01 2010-01-01 false Tolerance for diverter-type mechanical samplers. 801.5 Section 801.5 Agriculture Regulations of the Department of Agriculture (Continued) GRAIN INSPECTION... mechanical samplers. The maintenance tolerance for diverter-type mechanical samplers (primary, or primary and...
30 CFR 77.400 - Mechanical equipment guards.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Mechanical equipment guards. 77.400 Section 77.400 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND... Safeguards for Mechanical Equipment § 77.400 Mechanical equipment guards. (a) Gears; sprockets; chains; drive...
14 CFR 121.705 - Mechanical interruption summary report.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Mechanical interruption summary report. 121... OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Records and Reports § 121.705 Mechanical... known or suspected mechanical difficulties or malfunctions that are not required to be reported under...
47 CFR 1.357 - Mechanical reproductions as evidence.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 47 Telecommunication 1 2010-10-01 2010-10-01 false Mechanical reproductions as evidence. 1.357... Proceedings Evidence § 1.357 Mechanical reproductions as evidence. Unless offered for the sole purpose of attempting to prove or demonstrate sound effect, mechanical or physical reproductions of sound waves shall...
21 CFR 876.4500 - Mechanical lithotriptor.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Mechanical lithotriptor. 876.4500 Section 876.4500...) MEDICAL DEVICES GASTROENTEROLOGY-UROLOGY DEVICES Surgical Devices § 876.4500 Mechanical lithotriptor. (a) Identification. A mechanical lithotriptor is a device with steel jaws that is inserted into the urinary bladder...
14 CFR 91.1417 - CAMP: Mechanical interruption summary report.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false CAMP: Mechanical interruption summary... Ownership Operations Program Management § 91.1417 CAMP: Mechanical interruption summary report. Each program... route, caused by known or suspected mechanical difficulties or malfunctions that are not required to be...
46 CFR 113.35-15 - Mechanical engine order telegraph systems; application.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 46 Shipping 4 2012-10-01 2012-10-01 false Mechanical engine order telegraph systems; application...) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Engine Order Telegraph Systems § 113.35-15 Mechanical engine order telegraph systems; application. If a mechanical engine order telegraph...
46 CFR 113.35-15 - Mechanical engine order telegraph systems; application.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 46 Shipping 4 2013-10-01 2013-10-01 false Mechanical engine order telegraph systems; application...) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Engine Order Telegraph Systems § 113.35-15 Mechanical engine order telegraph systems; application. If a mechanical engine order telegraph...
46 CFR 113.35-15 - Mechanical engine order telegraph systems; application.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 46 Shipping 4 2014-10-01 2014-10-01 false Mechanical engine order telegraph systems; application...) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Engine Order Telegraph Systems § 113.35-15 Mechanical engine order telegraph systems; application. If a mechanical engine order telegraph...
46 CFR 113.35-15 - Mechanical engine order telegraph systems; application.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 46 Shipping 4 2011-10-01 2011-10-01 false Mechanical engine order telegraph systems; application...) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Engine Order Telegraph Systems § 113.35-15 Mechanical engine order telegraph systems; application. If a mechanical engine order telegraph...
47 CFR 51.915 - Recovery mechanism for price cap carriers.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 47 Telecommunication 3 2013-10-01 2013-10-01 false Recovery mechanism for price cap carriers. 51... SERVICES (CONTINUED) INTERCONNECTION Transitional Access Service Pricing § 51.915 Recovery mechanism for... recover certain revenues, through the recovery mechanism outlined below, to implement reforms adopted in...
47 CFR 51.915 - Recovery mechanism for price cap carriers.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 47 Telecommunication 3 2012-10-01 2012-10-01 false Recovery mechanism for price cap carriers. 51... SERVICES (CONTINUED) INTERCONNECTION Transitional Access Service Pricing § 51.915 Recovery mechanism for... recover certain revenues, through the recovery mechanism outlined below, to implement reforms adopted in...
47 CFR 51.915 - Recovery mechanism for price cap carriers.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 47 Telecommunication 3 2014-10-01 2014-10-01 false Recovery mechanism for price cap carriers. 51... SERVICES (CONTINUED) INTERCONNECTION Transitional Access Service Pricing § 51.915 Recovery mechanism for... recover certain revenues, through the recovery mechanism outlined below, to implement reforms adopted in...
30 CFR 70.207 - Bimonthly sampling; mechanized mining units.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Bimonthly sampling; mechanized mining units. 70... Bimonthly sampling; mechanized mining units. (a) Each operator shall take five valid respirable dust samples from the designated occupation in each mechanized mining unit during each bimonthly period beginning...
Fan, Qianrui; Wang, Wenyu; Hao, Jingcan; He, Awen; Wen, Yan; Guo, Xiong; Wu, Cuiyan; Ning, Yujie; Wang, Xi; Wang, Sen; Zhang, Feng
2017-08-01
Neuroticism is a fundamental personality trait with significant genetic determinant. To identify novel susceptibility genes for neuroticism, we conducted an integrative analysis of genomic and transcriptomic data of genome wide association study (GWAS) and expression quantitative trait locus (eQTL) study. GWAS summary data was driven from published studies of neuroticism, totally involving 170,906 subjects. eQTL dataset containing 927,753 eQTLs were obtained from an eQTL meta-analysis of 5311 samples. Integrative analysis of GWAS and eQTL data was conducted by summary data-based Mendelian randomization (SMR) analysis software. To identify neuroticism associated gene sets, the SMR analysis results were further subjected to gene set enrichment analysis (GSEA). The gene set annotation dataset (containing 13,311 annotated gene sets) of GSEA Molecular Signatures Database was used. SMR single gene analysis identified 6 significant genes for neuroticism, including MSRA (p value=2.27×10 -10 ), MGC57346 (p value=6.92×10 -7 ), BLK (p value=1.01×10 -6 ), XKR6 (p value=1.11×10 -6 ), C17ORF69 (p value=1.12×10 -6 ) and KIAA1267 (p value=4.00×10 -6 ). Gene set enrichment analysis observed significant association for Chr8p23 gene set (false discovery rate=0.033). Our results provide novel clues for the genetic mechanism studies of neuroticism. Copyright © 2017. Published by Elsevier Inc.
ERIC Educational Resources Information Center
Field, J. H.
2011-01-01
It is shown how the time-dependent Schrodinger equation may be simply derived from the dynamical postulate of Feynman's path integral formulation of quantum mechanics and the Hamilton-Jacobi equation of classical mechanics. Schrodinger's own published derivations of quantum wave equations, the first of which was also based on the Hamilton-Jacobi…
CONFIG: Integrated engineering of systems and their operation
NASA Technical Reports Server (NTRS)
Malin, Jane T.; Ryan, Dan; Fleming, Land
1994-01-01
This article discusses CONFIG 3, a prototype software tool that supports integrated conceptual design evaluation from early in the product life cycle, by supporting isolated or integrated modeling, simulation, and analysis of the function, structure, behavior, failures and operations of system designs. Integration and reuse of models is supported in an object-oriented environment providing capabilities for graph analysis and discrete event simulation. CONFIG supports integration among diverse modeling approaches (component view, configuration or flow path view, and procedure view) and diverse simulation and analysis approaches. CONFIG is designed to support integrated engineering in diverse design domains, including mechanical and electro-mechanical systems, distributed computer systems, and chemical processing and transport systems.
Attention modulates trans-saccadic integration.
Stewart, Emma E M; Schütz, Alexander C
2018-01-01
With every saccade, humans must reconcile the low resolution peripheral information available before a saccade, with the high resolution foveal information acquired after the saccade. While research has shown that we are able to integrate peripheral and foveal vision in a near-optimal manner, it is still unclear which mechanisms may underpin this important perceptual process. One potential mechanism that may moderate this integration process is visual attention. Pre-saccadic attention is a well documented phenomenon, whereby visual attention shifts to the location of an upcoming saccade before the saccade is executed. While it plays an important role in other peri-saccadic processes such as predictive remapping, the role of attention in the integration process is as yet unknown. This study aimed to determine whether the presentation of an attentional distractor during a saccade impaired trans-saccadic integration, and to measure the time-course of this impairment. Results showed that presenting an attentional distractor impaired integration performance both before saccade onset, and during the saccade, in selected subjects who showed integration in the absence of a distractor. This suggests that visual attention may be a mechanism that facilitates trans-saccadic integration. Copyright © 2017 The Author(s). Published by Elsevier Ltd.. All rights reserved.
Computational structural mechanics for engine structures
NASA Technical Reports Server (NTRS)
Chamis, Christos C.
1988-01-01
The computational structural mechanics (CSM) program at Lewis encompasses the formulation and solution of structural mechanics problems and the development of integrated software systems to computationally simulate the performance, durability, and life of engine structures. It is structured to supplement, complement, and, whenever possible, replace costly experimental efforts. Specific objectives are to investigate unique advantages of parallel and multiprocessing for reformulating and solving structural mechanics and formulating and solving multidisciplinary mechanics and to develop integrated structural system computational simulators for predicting structural performance, evaluating newly developed methods, and identifying and prioritizing improved or missing methods.
Computational structural mechanics for engine structures
NASA Technical Reports Server (NTRS)
Chamis, Christos C.
1989-01-01
The computational structural mechanics (CSM) program at Lewis encompasses the formulation and solution of structural mechanics problems and the development of integrated software systems to computationally simulate the performance, durability, and life of engine structures. It is structured to supplement, complement, and, whenever possible, replace costly experimental efforts. Specific objectives are to investigate unique advantages of parallel and multiprocessing for reformulating and solving structural mechanics and formulating and solving multidisciplinary mechanics and to develop integrated structural system computational simulators for predicting structural performance, evaluating newly developed methods, and identifying and prioritizing improved or missing methods.
An Approximate Dissipation Function for Large Strain Rubber Thermo-Mechanical Analyses
NASA Technical Reports Server (NTRS)
Johnson, Arthur R.; Chen, Tzi-Kang
2003-01-01
Mechanically induced viscoelastic dissipation is difficult to compute. When the constitutive model is defined by history integrals, the formula for dissipation is a double convolution integral. Since double convolution integrals are difficult to approximate, coupled thermo-mechanical analyses of highly viscous rubber-like materials cannot be made with most commercial finite element software. In this study, we present a method to approximate the dissipation for history integral constitutive models that represent Maxwell-like materials without approximating the double convolution integral. The method requires that the total stress can be separated into elastic and viscous components, and that the relaxation form of the constitutive law is defined with a Prony series. Numerical data is provided to demonstrate the limitations of this approximate method for determining dissipation. Rubber cylinders with imbedded steel disks and with an imbedded steel ball are dynamically loaded, and the nonuniform heating within the cylinders is computed.
A review of path-independent integrals in elastic-plastic fracture mechanics
NASA Technical Reports Server (NTRS)
Kim, Kwang S.; Orange, Thomas W.
1988-01-01
The objective of this paper is to review the path-independent (P-I) integrals in elastic plastic fracture mechanics which have been proposed in recent years to overcome the limitations imposed on the J-integral. The P-I integrals considered are the J-integral by Rice (1968), the thermoelastic P-I integrals by Wilson and Yu (1979) and Gurtin (1979), the J-integral by Blackburn (1972), the J(theta)-integral by Ainsworth et al. (1978), the J-integral by Kishimoto et al. (1980), and the Delta-T(p) and Delta T(p)-asterisk integrals by Alturi et al. (1982). The theoretical foundation of the P-I integrals is examined with an emphasis on whether or not the path independence is maintained in the presence of nonproportional loading and unloading in the plastic regime, thermal gradient, and material inhomogeneities. The simularities, difference, salient features, and limitations of the P-I integrals are discussed. Comments are also made with regard to the physical meaning, the possibility of experimental measurement, and computational aspects.
A review of path-independent integrals in elastic-plastic fracture mechanics, task 4
NASA Technical Reports Server (NTRS)
Kim, K. S.
1985-01-01
The path independent (P-I) integrals in elastic plastic fracture mechanics which have been proposed in recent years to overcome the limitations imposed on the J integral are reviewed. The P-I integrals considered herein are the J integral by Rice, the thermoelastic P-I integrals by Wilson and Yu and by Gurtin, the J* integral by Blackburn, the J sub theta integral by Ainsworth et al., the J integral by Kishimoto et al., and the delta T sub p and delta T* sub p integrals by Atluri et al. The theoretical foundation of these P-I integrals is examined with emphasis on whether or not path independence is maintained in the presence of nonproportional loading and unloading in the plastic regime, thermal gradients, and material inhomogeneities. The similarities, differences, salient features, and limitations of these P-I integrals are discussed. Comments are also made with regard to the physical meaning, the possibility of experimental measurement, and computational aspects.
Tu, Thomas; Budzinska, Magdalena A; Vondran, Florian W R; Shackel, Nicholas A; Urban, Stephan
2018-02-07
Chronic infection by the Hepatitis B Virus (HBV) is the major contributor to liver disease worldwide. Though HBV replicates via a nuclear episomal DNA (cccDNA), integration of HBV DNA into the host cell genome is regularly observed in the liver of infected patients. While reported as a pro-oncogenic alteration, the mechanism(s) and timing of HBV DNA integration are not well-understood, chiefly due to the lack of in vitro infection models that have detectable integration events. Here, we have established an in vitro system in which integration can be reliably detected following HBV infection. We measured HBV DNA integration using inverse nested PCR in primary human hepatocytes, HepaRG-NTCP, HepG2-NTCP, and Huh7-NTCP cells after HBV infection. Integration was detected in all cell types at a rate of >1 per 10000 cells, with the most consistent detection in Huh7-NTCP cells. Integration rate remained stable between 3 and 9 days post-infection. HBV DNA integration was efficiently blocked by treatment with 200nM of the HBV entry inhibitor Myrcludex B, but not with 10μM Tenofovir, 100U Interferon alpha, or 1μM of the capsid assembly inhibitor GLS4. This suggests integration of HBV DNA occurs immediately after infection of hepatocytes and is likely independent of de novo HBV replication in this model. Site analysis revealed that HBV DNA integrations were distributed over the entire human genome. Further, integrated HBV DNA sequences were consistent with double-stranded linear HBV DNA being the major precursor. Thus, we have established an in vitro system to interrogate the mechanisms of HBV DNA integration. Importance Hepatitis B Virus (HBV) is a common blood-borne pathogen and, following a chronic infection, can cause liver cancer and liver cirrhosis. Integration of HBV DNA into the host genome occurs in all known members of the hepadnaviridae family, despite this form not being necessary for viral replication. HBV DNA integration has been reported to drive liver cancer formation and persistence of virus infection. However, when and the mechanism(s) by which HBV DNA integration occurs is not clear. Here, we have developed and characterized an in vitro system to reliably detect HBV DNA integrations that result from a true HBV infection event and that closely resemble those found in patient tissues. Using this model, we show that integration already occurs when the infection is first established. Importantly, we provide here a system to analyze molecular factors involved in HBV integration, which can be used to develop strategies to halt its formation. Copyright © 2018 American Society for Microbiology.
40 CFR 147.3010 - Mechanical integrity tests.
Code of Federal Regulations, 2011 CFR
2011-07-01
... monitoring of annulus pressure listed in § 146.8(b)(1) of this chapter will only be acceptable if preceded by a pressure test, using liquid or gas that clearly demonstrates that mechanical integrity exists at the time of the pressure test. ...
40 CFR 147.3010 - Mechanical integrity tests.
Code of Federal Regulations, 2014 CFR
2014-07-01
... monitoring of annulus pressure listed in § 146.8(b)(1) of this chapter will only be acceptable if preceded by a pressure test, using liquid or gas that clearly demonstrates that mechanical integrity exists at the time of the pressure test. ...
40 CFR 147.3010 - Mechanical integrity tests.
Code of Federal Regulations, 2012 CFR
2012-07-01
... monitoring of annulus pressure listed in § 146.8(b)(1) of this chapter will only be acceptable if preceded by a pressure test, using liquid or gas that clearly demonstrates that mechanical integrity exists at the time of the pressure test. ...
40 CFR 147.3010 - Mechanical integrity tests.
Code of Federal Regulations, 2013 CFR
2013-07-01
... monitoring of annulus pressure listed in § 146.8(b)(1) of this chapter will only be acceptable if preceded by a pressure test, using liquid or gas that clearly demonstrates that mechanical integrity exists at the time of the pressure test. ...
Evaluation of Vertical Integrated Nanogenerator Performances in Flexion
NASA Astrophysics Data System (ADS)
Tao, R.; Hinchet, R.; Ardila, G.; Mouis, M.
2013-12-01
Piezoelectric nanowires have attracted great interest as new building blocks of mechanical energy harvesting systems. This paper presents the design improvements of mechanical energy harvesters integrating vertical ZnO piezoelectric nanowires onto a Silicon or plastic membrane. We have calculated the energy generation and conversion performance of ZnO nanowires based vertical integrated nanogenerators in flexion mode. We show that in flexion mode ZnO nanowires are superior to bulk ZnO layer. Both mechanical and electrical effects of matrix materials on the potential generation and energy conversion are discussed, in the aim of guiding further improvement of nanogenerator performance.
A universal data access and protocol integration mechanism for smart home
NASA Astrophysics Data System (ADS)
Shao, Pengfei; Yang, Qi; Zhang, Xuan
2013-03-01
With the lack of standardized or completely missing communication interfaces in home electronics, there is no perfect solution to address every aspect in smart homes based on existing protocols and technologies. In addition, the central control unit (CCU) of smart home system working point-to-point between the multiple application interfaces and the underlying hardware interfaces leads to its complicated architecture and unpleasant performance. A flexible data access and protocol integration mechanism is required. The current paper offers a universal, comprehensive data access and protocol integration mechanism for a smart home. The universal mechanism works as a middleware adapter with unified agreements of the communication interfaces and protocols, offers an abstraction of the application level from the hardware specific and decoupling the hardware interface modules from the application level. Further abstraction for the application interfaces and the underlying hardware interfaces are executed based on adaption layer to provide unified interfaces for more flexible user applications and hardware protocol integration. This new universal mechanism fundamentally changes the architecture of the smart home and in some way meets the practical requirement of smart homes more flexible and desirable.
9 CFR 312.10 - Official mark for maintaining the identity and integrity of samples.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Official mark for maintaining the identity and integrity of samples. 312.10 Section 312.10 Animals and Animal Products FOOD SAFETY AND... of the Federal Meat Inspection Act shall bear the designation “Sample Seal” accompanied by the...
9 CFR 381.112 - Official mark for maintaining the identity and integrity of samples.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Official mark for maintaining the identity and integrity of samples. 381.112 Section 381.112 Animals and Animal Products FOOD SAFETY AND... Inspection Act shall bear the designation “Sample Seal” accompanied by the official USDA logo as shown below...
Code of Federal Regulations, 2012 CFR
2012-10-01
... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Inclusion of determination of contractor fault in Federal Awardee Performance and Integrity Information System (FAPIIS). 209.105... Contractors 209.105-2-70 Inclusion of determination of contractor fault in Federal Awardee Performance and...
Code of Federal Regulations, 2014 CFR
2014-10-01
... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Inclusion of determination of contractor fault in Federal Awardee Performance and Integrity Information System (FAPIIS). 209.105... Contractors 209.105-2-70 Inclusion of determination of contractor fault in Federal Awardee Performance and...
Code of Federal Regulations, 2013 CFR
2013-10-01
... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Inclusion of determination of contractor fault in Federal Awardee Performance and Integrity Information System (FAPIIS). 209.105... Contractors 209.105-2-70 Inclusion of determination of contractor fault in Federal Awardee Performance and...
Code of Federal Regulations, 2011 CFR
2011-10-01
... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Inclusion of determination of contractor fault in Federal Awardee Performance and Integrity Information System (FAPIIS). 209.105... Contractors 209.105-2-70 Inclusion of determination of contractor fault in Federal Awardee Performance and...
42 CFR 93.217 - Office of Research Integrity or ORI.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 42 Public Health 1 2010-10-01 2010-10-01 false Office of Research Integrity or ORI. 93.217 Section 93.217 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH ASSESSMENTS AND HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Definitions §...
46 CFR 111.59-3 - No mechanical cooling.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 46 Shipping 4 2011-10-01 2011-10-01 false No mechanical cooling. 111.59-3 Section 111.59-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Busways § 111.59-3 No mechanical cooling. A busway must not need mechanical cooling...
46 CFR 111.59-3 - No mechanical cooling.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 46 Shipping 4 2014-10-01 2014-10-01 false No mechanical cooling. 111.59-3 Section 111.59-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Busways § 111.59-3 No mechanical cooling. A busway must not need mechanical cooling...
46 CFR 111.59-3 - No mechanical cooling.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 46 Shipping 4 2013-10-01 2013-10-01 false No mechanical cooling. 111.59-3 Section 111.59-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Busways § 111.59-3 No mechanical cooling. A busway must not need mechanical cooling...
46 CFR 111.59-3 - No mechanical cooling.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 46 Shipping 4 2012-10-01 2012-10-01 false No mechanical cooling. 111.59-3 Section 111.59-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Busways § 111.59-3 No mechanical cooling. A busway must not need mechanical cooling...
49 CFR 236.102 - Semaphore or searchlight signal mechanism.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 49 Transportation 4 2010-10-01 2010-10-01 false Semaphore or searchlight signal mechanism. 236.102... Instructions: All Systems Inspections and Tests; All Systems § 236.102 Semaphore or searchlight signal mechanism. (a) Semaphore signal mechanism shall be inspected at least once every six months, and tests of...
46 CFR 111.59-3 - No mechanical cooling.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 46 Shipping 4 2010-10-01 2010-10-01 false No mechanical cooling. 111.59-3 Section 111.59-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Busways § 111.59-3 No mechanical cooling. A busway must not need mechanical cooling...
49 CFR 236.304 - Mechanical locking or same protection effected by circuits.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 49 Transportation 4 2010-10-01 2010-10-01 false Mechanical locking or same protection effected by..., AND APPLIANCES Interlocking Standards § 236.304 Mechanical locking or same protection effected by circuits. Mechanical locking, or the same protection effected by means of circuits, shall be provided. ...
46 CFR 113.35-9 - Mechanical engine order telegraph systems.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 46 Shipping 4 2010-10-01 2010-10-01 false Mechanical engine order telegraph systems. 113.35-9... COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Engine Order Telegraph Systems § 113.35-9 Mechanical engine order telegraph systems. (a) Each mechanical engine order telegraph system must consist of transmitters and...
46 CFR 56.30-35 - Gasketed mechanical couplings.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 46 Shipping 2 2010-10-01 2010-10-01 false Gasketed mechanical couplings. 56.30-35 Section 56.30-35... APPURTENANCES Selection and Limitations of Piping Joints § 56.30-35 Gasketed mechanical couplings. (a) This... Inspection. (b) Gasketed mechanical couplings may be used within the service limitations of pressure...
21 CFR 872.3530 - Mechanical denture cleaner.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Mechanical denture cleaner. 872.3530 Section 872...) MEDICAL DEVICES DENTAL DEVICES Prosthetic Devices § 872.3530 Mechanical denture cleaner. (a) Identification. A mechanical denture cleaner is a device, usually AC-powered, that consists of a container for...
29 CFR 1915.34 - Mechanical paint removers.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 29 Labor 7 2010-07-01 2010-07-01 false Mechanical paint removers. 1915.34 Section 1915.34 Labor... Preservation § 1915.34 Mechanical paint removers. (a) Power tools. (1) Employees engaged in the removal of... confined space, mechanical exhaust ventilation sufficient to keep the dust concentration to a minimum shall...
30 CFR 33.23 - Mechanical positioning of parts.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Mechanical positioning of parts. 33.23 Section... MINES Dust-Collector Requirements § 33.23 Mechanical positioning of parts. All parts of a unit that are essential to the dust-collection feature shall be provided with suitable mechanical means for positioning...
49 CFR 236.308 - Mechanical or electric locking or electric circuits; requisites.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 49 Transportation 4 2010-10-01 2010-10-01 false Mechanical or electric locking or electric..., AND APPLIANCES Interlocking Standards § 236.308 Mechanical or electric locking or electric circuits; requisites. Mechanical or electric locking or electric circuits shall be installed to prevent signals from...
21 CFR 211.68 - Automatic, mechanical, and electronic equipment.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 4 2011-04-01 2011-04-01 false Automatic, mechanical, and electronic equipment. 211.68 Section 211.68 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN... Equipment § 211.68 Automatic, mechanical, and electronic equipment. (a) Automatic, mechanical, or electronic...
21 CFR 211.68 - Automatic, mechanical, and electronic equipment.
Code of Federal Regulations, 2012 CFR
2012-04-01
... 21 Food and Drugs 4 2012-04-01 2012-04-01 false Automatic, mechanical, and electronic equipment. 211.68 Section 211.68 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN... Equipment § 211.68 Automatic, mechanical, and electronic equipment. (a) Automatic, mechanical, or electronic...
An Educational Program of Mechatronics for Multidisciplinary Knowledge Acquisition
NASA Astrophysics Data System (ADS)
Watanuki, Keiichi; Kojima, Kazuyuki
Recently, as the technologies surrounding mechanical engineering have improved remarkably, the expectations for students who graduate from departments of mechanical engineering have increased. For example, in order to develop a mechatronics system, a student needs to integrate a wide variety of technologies, such as mechanical engineering, electrical and electronics engineering, and information technology. Therefore, from the perspective of educators, the current education system, which stresses expertizing each technology, should be replaced by an education system that stresses integrating multidisciplinary knowledge. In this paper, a trial education program for students of the department of mechanical engineering in our university, in which students are required to integrate multidisciplinary knowledge in order to develop a biologically-based robot, is described. Finally, the efficacy of the program is analyzed.
Two mechanisms of constructive recollection: Perceptual recombination and conceptual fluency.
Doss, Manoj K; Bluestone, Maximilian R; Gallo, David A
2016-11-01
Recollection is constructive and prone to distortion, but the mechanisms through which recollections can become embellished with rich yet illusory details are still debated. According to the conceptual fluency hypothesis, abstract semantic or conceptual activation increases the familiarity of a nonstudied event, causing one to falsely attribute imagined features to actual perception. In contrast, according to the perceptual recombination hypothesis, details from actually perceived events are partially recollected and become erroneously bound to a nonstudied event, again causing a detailed yet false recollection. Here, we report the first experiments aimed at disentangling these 2 mechanisms. Participants imagined pictures of common objects, and then they saw an actual picture of some of the imagined objects. We next presented misinformation associated with these studied items, designed to increase conceptual fluency (i.e., semantically related words) or perceptual recombination (i.e., perceptually similar picture fragments). Finally, we tested recollection for the originally seen pictures using verbal labels as retrieval cues. Consistent with conceptual fluency, processing-related words increased false recollection of pictures that were never seen, and consistent with perceptual recombination, processing picture fragments further increased false recollection. We also found that conceptual fluency was more short-lived than perceptual recombination, further dissociating these 2 mechanisms. These experiments provide strong evidence that conceptual fluency and perceptual recombination independently contribute to the constructive aspects of recollection. (PsycINFO Database Record (c) 2016 APA, all rights reserved).
Development of Novel Integrated Antennas for CubeSats
NASA Technical Reports Server (NTRS)
Jackson, David; Fink, Patrick W.; Martinez, Andres; Petro, Andrew
2015-01-01
The Development of Novel Integrated Antennas for CubeSats project is directed at the development of novel antennas for CubeSats to replace the bulky and obtrusive antennas (e.g., whip antennas) that are typically used. The integrated antennas will not require mechanical deployment and thus will allow future CubeSats to avoid potential mechanical problems and therefore improve mission reliability. Furthermore, the integrated antennas will have improved functionality and performance, such as circular polarization for improved link performance, compared with the conventional antennas currently used on CubeSats.
Mujica-Parodi, Lilianne R; Cha, Jiook; Gao, Jonathan
2017-01-01
Here we provide an integrative review of basic control circuits, and introduce techniques by which their regulation can be quantitatively measured using human neuroimaging. We illustrate the utility of the control systems approach using four human neuroimaging threat detection studies ( N = 226), to which we applied circuit-wide analyses in order to identify the key mechanism underlying individual variation. In so doing, we build upon the canonical prefrontal-limbic control system to integrate circuit-wide influence from the inferior frontal gyrus (IFG). These were incorporated into a computational control systems model constrained by neuroanatomy and designed to replicate our experimental data. In this model, the IFG acts as an informational set point, gating signals between the primary prefrontal-limbic negative feedback loop and its cortical information-gathering loop. Along the cortical route, if the sensory cortex provides sufficient information to make a threat assessment, the signal passes to the ventromedial prefrontal cortex (vmPFC), whose threat-detection threshold subsequently modulates amygdala outputs. However, if signal outputs from the sensory cortex do not provide sufficient information during the first pass, the signal loops back to the sensory cortex, with each cycle providing increasingly fine-grained processing of sensory data. Simulations replicate IFG (chaotic) dynamics experimentally observed at both ends at the threat-detection spectrum. As such, they identify distinct types of IFG disconnection from the circuit, with associated clinical outcomes. If IFG thresholds are too high, the IFG and sensory cortex cycle for too long; in the meantime the coarse-grained (excitatory) pathway will dominate, biasing ambiguous stimuli as false positives. On the other hand, if cortical IFG thresholds are too low, the inhibitory pathway will suppress the amygdala without cycling back to the sensory cortex for much-needed fine-grained sensory cortical data, biasing ambiguous stimuli as false negatives. Thus, the control systems model provides a consistent mechanism for IFG regulation, capable of producing results consistent with our data for the full spectrum of threat-detection: from fearful to optimal to reckless. More generally, it illustrates how quantitative characterization of circuit dynamics can be used to unify a fundamental dimension across psychiatric affective symptoms, with implications for populations that range from anxiety disorders to addiction.
Design, Fabrication, Characterization and Modeling of Integrated Functional Materials
2012-10-01
mechanical , optical, etc.), the connection to real-world applications and devices also requires the seamless integration of dimensions (nano, micro...underlying mechanism of magnetic interactions between graphene- mediated nanoparticles, and proximity effects at the interface between the nanoparticles and... mechanism for induced magnetic anisotropy in these alloys has been an area of active inquiry. Recently, Ohodnicki Jr et al. [14] reported on the
49 CFR 236.765 - Locking, mechanical.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 49 Transportation 4 2010-10-01 2010-10-01 false Locking, mechanical. 236.765 Section 236.765 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION... Locking, mechanical. An arrangement of locking bars, dogs, tappets, cross locking and other apparatus by...
Apparatus for integrating a rigid structure into a flexible wall of an inflatable structure
NASA Technical Reports Server (NTRS)
Johnson, Christopher J. (Inventor); Patterson, Ross M. (Inventor); Spexarth, Gary R. (Inventor)
2009-01-01
For an inflatable structure having a flexible outer shell or wall structure having a flexible restraint layer comprising interwoven, load-bearing straps, apparatus for integrating one or more substantially rigid members into the flexible shell. For each rigid member, a corresponding opening is formed through the flexible shell for receiving the rigid member. A plurality of connection devices are mounted on the rigid member for receiving respective ones of the load-bearing straps. In one embodiment, the connection devices comprise inner connecting mechanisms and outer connecting mechanisms, the inner and outer connecting mechanisms being mounted on the substantially rigid structure and spaced along a peripheral edge portion of the structure in an interleafed array in which respective outer connecting mechanisms are interposed between adjacent pairs of inner connecting mechanisms, the outer connecting mechanisms projecting outwardly from the peripheral edge portion of the substantially rigid structure beyond the adjacent inner connecting mechanisms to form a staggered array of connecting mechanisms extending along the panel structure edge portion. In one embodiment, the inner and outer connecting mechanisms form part of an integrated, structure rotatably mounted on the rigid member peripheral edge portion.
Multiple methods integration for structural mechanics analysis and design
NASA Technical Reports Server (NTRS)
Housner, J. M.; Aminpour, M. A.
1991-01-01
A new research area of multiple methods integration is proposed for joining diverse methods of structural mechanics analysis which interact with one another. Three categories of multiple methods are defined: those in which a physical interface are well defined; those in which a physical interface is not well-defined, but selected; and those in which the interface is a mathematical transformation. Two fundamental integration procedures are presented that can be extended to integrate various methods (e.g., finite elements, Rayleigh Ritz, Galerkin, and integral methods) with one another. Since the finite element method will likely be the major method to be integrated, its enhanced robustness under element distortion is also examined and a new robust shell element is demonstrated.
ERIC Educational Resources Information Center
Potvin, Patrice; Skelling-Desmeules, Yannick; Sy, Ousmane
2015-01-01
This article describes the design of a misconception diagnostic test about fire-related phenomena. It proposes a new test format in which a certainty-measuring tier has been integrated into each of the true/false response choices. This format is argued to be easier for teachers to use than the increasingly popular three-tier format. First, we…
Integrating Computational Chemistry into a Course in Classical Thermodynamics
ERIC Educational Resources Information Center
Martini, Sheridan R.; Hartzell, Cynthia J.
2015-01-01
Computational chemistry is commonly addressed in the quantum mechanics course of undergraduate physical chemistry curricula. Since quantum mechanics traditionally follows the thermodynamics course, there is a lack of curricula relating computational chemistry to thermodynamics. A method integrating molecular modeling software into a semester long…
NASA Astrophysics Data System (ADS)
Parshin, D. A.; Manzhirov, A. V.
2018-04-01
Quasistatic mechanical problems on additive manufacturing aging viscoelastic solids are investigated. The processes of piecewise-continuous accretion of such solids are considered. The consideration is carried out in the framework of linear mechanics of growing solids. A theorem about commutativity of the integration over an arbitrary surface increasing in the solid growing process and the time-derived integral operator of viscoelasticity with a limit depending on the solid point is proved. This theorem provides an efficient way to construct on the basis of Saint-Venant principle solutions of nonclassical boundary-value problems for describing the mechanical behaviour of additively formed solids with integral satisfaction of boundary conditions on the surfaces expanding due to the additional material influx to the formed solid. The constructed solutions will retrace the evolution of the stress-strain state of the solids under consideration during and after the processes of their additive formation. An example of applying the proved theorem is given.
Regulation of multispanning membrane protein topology via post-translational annealing.
Van Lehn, Reid C; Zhang, Bin; Miller, Thomas F
2015-09-26
The canonical mechanism for multispanning membrane protein topogenesis suggests that protein topology is established during cotranslational membrane integration. However, this mechanism is inconsistent with the behavior of EmrE, a dual-topology protein for which the mutation of positively charged loop residues, even close to the C-terminus, leads to dramatic shifts in its topology. We use coarse-grained simulations to investigate the Sec-facilitated membrane integration of EmrE and its mutants on realistic biological timescales. This work reveals a mechanism for regulating membrane-protein topogenesis, in which initially misintegrated configurations of the proteins undergo post-translational annealing to reach fully integrated multispanning topologies. The energetic barriers associated with this post-translational annealing process enforce kinetic pathways that dictate the topology of the fully integrated proteins. The proposed mechanism agrees well with the experimentally observed features of EmrE topogenesis and provides a range of experimentally testable predictions regarding the effect of translocon mutations on membrane protein topogenesis.
Early False-Belief Understanding.
Scott, Rose M; Baillargeon, Renée
2017-04-01
Intense controversy surrounds the question of when children first understand that others can hold false beliefs. Results from traditional tasks suggest that false-belief understanding does not emerge until about 4 years of age and constitutes a major developmental milestone in social cognition. By contrast, results from nontraditional tasks, which have steadily accumulated over the past 10 years, suggest that false-belief understanding is already present in infants (under age 2 years) and toddlers (age 2-3 years) and thus forms an integral part of social cognition from early in life. Here we first present an overview of the findings from nontraditional tasks. We then return to traditional tasks and argue that processing difficulties, rather than limitations in false-belief understanding, account for young children's failure at these tasks. Copyright © 2017 Elsevier Ltd. All rights reserved.
Schouten, M C M; Karst, W A; van der Stel, H F; Teeuw, A H; van de Putte, E M
2016-01-01
A false accusation of child abuse has a major impact on child and family. Conversely, a missed diagnosis of child abuse may have significant and lifelong consequences for the child. For health professionals the assessment of the nature of the injury and differentiating between accidental and inflicted injury, disease manifestation or a physiological phenomenon can be challenging. For adequate determination of the cause of injury, an integrated approach including paediatric knowledge and forensic medical expertise is essential. Therefore, a national expertise centre for child abuse (LECK) was established in the Netherlands in 2014. The first results of this integrated approach are described and illustrated with three case reports. Case A, a 7-month-old boy with an accidental humerus fracture. Case B, an 8-year-old boy with a false positive suspicion of child abuse who was eventually diagnosed with Henoch-Schönlein syndrome. Case C, boy of 3 months with bruises and a metaphyseal fracture of the femur, both highly suspected of being inflicted injury.
ERIC Educational Resources Information Center
Low, Jason; Simpson, Samantha
2012-01-01
Executive function mechanisms underpinning language-related effects on theory of mind understanding were examined in a sample of 165 preschoolers. Verbal labels were manipulated to identify relevant perspectives on an explicit false belief task. In Experiment 1 with 4-year-olds (N = 74), false belief reasoning was superior in the fully and…
Jou, Jerwen; Arredondo, Mario L; Li, Cheng; Escamilla, Eric E; Zuniga, Richard
2017-10-01
In this study, the number of semantic associates in Deese-Roediger-McDermott (DRM) lists was varied from 4 to 14 in a modified Sternberg paradigm. The false alarm (FA) and correct rejection (CR) reaction time (RT)/memory-set size (MSS) functions of critical lures showed a cross-over interaction at approximately MSS 7, suggesting a reversal of the relative dominance between these two responses to the critical lure at this point and also indicating the location of the boundary between the sub- and supraspan MSS. For the subspan lists, FA to critical lures was slower than CR, suggesting a slow, strategic mechanism driving the false memory. Conversely, for the supraspan lists, critical lure FA was faster than its CR, suggesting a spontaneous mechanism driving the false memory. Results of two experiments showed that an automatic, fast, and a slow, controlled process could be error-prone or error-corrective, depending on the length of the DRM memory list. Thus there is a dual retrieval process in false memory as in true memory. The findings can be explained by both the activation/monitoring and the fuzzy-trace theories.
NASA Astrophysics Data System (ADS)
Rashid, Faisal M.; Dennis, Emily L.; Villalon-Reina, Julio E.; Jin, Yan; Lewis, Jeffrey D.; York, Gerald E.; Thompson, Paul M.; Tate, David F.
2017-11-01
Mild traumatic brain injury (mTBI) is characterized clinically by a closed head injury involving differential or rotational movement of the brain inside the skull. Over 3 million mTBIs occur annually in the United States alone. Many of the individuals who sustain an mTBI go on to recover fully, but around 20% experience persistent symptoms. These symptoms often last for many weeks to several months. The thalamus, a structure known to serve as a global networking or relay system for the rest of the brain, may play a critical role in neurorehabiliation and its integrity and connectivity after injury may also affect cognitive outcomes. To examine the thalamus, conventional tractography methods to map corticothalamic pathways with diffusion-weighted MRI (DWI) lead to sparse reconstructions that may contain false positive fibers that are anatomically inaccurate. Using a specialized method to zero in on corticothalamic pathways with greater robustness, we noninvasively examined corticothalamic fiber projections using DWI, in 68 service members. We found significantly lower fractional anisotropy (FA), a measure of white matter microstructural integrity, in pathways projecting to the left pre- and postcentral gyri - consistent with sensorimotor deficits often found post-mTBI. Mapping of neural circuitry in mTBI may help to further our understanding of mechanisms underlying recovery post-TBI.
29 CFR 1926.859 - Mechanical demolition.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 29 Labor 8 2010-07-01 2010-07-01 false Mechanical demolition. 1926.859 Section 1926.859 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR CONSTRUCTION Demolition § 1926.859 Mechanical demolition. (a...
Code of Federal Regulations, 2010 CFR
2010-10-01
... 49 Transportation 4 2010-10-01 2010-10-01 false Mechanical locking removed or disarranged... § 236.326 Mechanical locking removed or disarranged; requirement for permitting train movements through interlocking. When mechanical locking of interlocking machine is being changed or is removed from the machine...
49 CFR 236.560 - Contact element, mechanical trip type; location with respect to rail.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 49 Transportation 4 2010-10-01 2010-10-01 false Contact element, mechanical trip type; location... Instructions; Locomotives § 236.560 Contact element, mechanical trip type; location with respect to rail. Contact element of automatic train stop device of the mechanical trip type shall be maintained at a height...
21 CFR 111.30 - What requirements apply to automated, mechanical, or electronic equipment?
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 2 2010-04-01 2010-04-01 false What requirements apply to automated, mechanical... Utensils § 111.30 What requirements apply to automated, mechanical, or electronic equipment? For any automated, mechanical, or electronic equipment that you use to manufacture, package, label, or hold a...
Code of Federal Regulations, 2011 CFR
2011-10-01
... 49 Transportation 2 2011-10-01 2011-10-01 false Oilfield service vehicles, mechanical displacement... § 173.5a Oilfield service vehicles, mechanical displacement meter provers, and roadway striping vehicles... CONTAINED * * * ” on the shipping paper for each movement on a public highway. (b) Mechanical displacement...
Code of Federal Regulations, 2013 CFR
2013-10-01
... 49 Transportation 2 2013-10-01 2013-10-01 false Oilfield service vehicles, mechanical displacement... § 173.5a Oilfield service vehicles, mechanical displacement meter provers, and roadway striping vehicles... CONTAINED * * * ” on the shipping paper for each movement on a public highway. (b) Mechanical displacement...
Code of Federal Regulations, 2012 CFR
2012-10-01
... 49 Transportation 2 2012-10-01 2012-10-01 false Oilfield service vehicles, mechanical displacement... § 173.5a Oilfield service vehicles, mechanical displacement meter provers, and roadway striping vehicles... CONTAINED * * * ” on the shipping paper for each movement on a public highway. (b) Mechanical displacement...
Code of Federal Regulations, 2014 CFR
2014-10-01
... 49 Transportation 2 2014-10-01 2014-10-01 false Oilfield service vehicles, mechanical displacement... § 173.5a Oilfield service vehicles, mechanical displacement meter provers, and roadway striping vehicles... CONTAINED * * * ” on the shipping paper for each movement on a public highway. (b) Mechanical displacement...
14 CFR 27.923 - Rotor drive system and control mechanism tests.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 14 Aeronautics and Space 1 2012-01-01 2012-01-01 false Rotor drive system and control mechanism....923 Rotor drive system and control mechanism tests. (a) Each part tested as prescribed in this section... affect test results may be conducted. (b) Each rotor drive system and control mechanism must be tested...
14 CFR 27.923 - Rotor drive system and control mechanism tests.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 14 Aeronautics and Space 1 2014-01-01 2014-01-01 false Rotor drive system and control mechanism....923 Rotor drive system and control mechanism tests. (a) Each part tested as prescribed in this section... affect test results may be conducted. (b) Each rotor drive system and control mechanism must be tested...
Asakura, Nobuhiko; Inui, Toshio
2016-01-01
Two apparently contrasting theories have been proposed to account for the development of children's theory of mind (ToM): theory-theory and simulation theory. We present a Bayesian framework that rationally integrates both theories for false belief reasoning. This framework exploits two internal models for predicting the belief states of others: one of self and one of others. These internal models are responsible for simulation-based and theory-based reasoning, respectively. The framework further takes into account empirical studies of a developmental ToM scale (e.g., Wellman and Liu, 2004): developmental progressions of various mental state understandings leading up to false belief understanding. By representing the internal models and their interactions as a causal Bayesian network, we formalize the model of children's false belief reasoning as probabilistic computations on the Bayesian network. This model probabilistically weighs and combines the two internal models and predicts children's false belief ability as a multiplicative effect of their early-developed abilities to understand the mental concepts of diverse beliefs and knowledge access. Specifically, the model predicts that children's proportion of correct responses on a false belief task can be closely approximated as the product of their proportions correct on the diverse belief and knowledge access tasks. To validate this prediction, we illustrate that our model provides good fits to a variety of ToM scale data for preschool children. We discuss the implications and extensions of our model for a deeper understanding of developmental progressions of children's ToM abilities. PMID:28082941
Asakura, Nobuhiko; Inui, Toshio
2016-01-01
Two apparently contrasting theories have been proposed to account for the development of children's theory of mind (ToM): theory-theory and simulation theory. We present a Bayesian framework that rationally integrates both theories for false belief reasoning. This framework exploits two internal models for predicting the belief states of others: one of self and one of others. These internal models are responsible for simulation-based and theory-based reasoning, respectively. The framework further takes into account empirical studies of a developmental ToM scale (e.g., Wellman and Liu, 2004): developmental progressions of various mental state understandings leading up to false belief understanding. By representing the internal models and their interactions as a causal Bayesian network, we formalize the model of children's false belief reasoning as probabilistic computations on the Bayesian network. This model probabilistically weighs and combines the two internal models and predicts children's false belief ability as a multiplicative effect of their early-developed abilities to understand the mental concepts of diverse beliefs and knowledge access. Specifically, the model predicts that children's proportion of correct responses on a false belief task can be closely approximated as the product of their proportions correct on the diverse belief and knowledge access tasks. To validate this prediction, we illustrate that our model provides good fits to a variety of ToM scale data for preschool children. We discuss the implications and extensions of our model for a deeper understanding of developmental progressions of children's ToM abilities.
ERIC Educational Resources Information Center
Franchetti, Matthew
2011-01-01
The purpose of this paper is to report the findings of the integration of a manufacturing case study to a freshman level mechanical engineering course at The University of Toledo. The approach to integrate this case study into the class was completed via weekly assignments analyzing the case, small group discussion, and weekly group discussion.…
NASA Astrophysics Data System (ADS)
Budhwani, Karim Ismail
The tremendous quality of life impact notwithstanding, cardiovascular diseases and Cancer add up to over US$ 700bn each year in financial costs alone. Aging and population growth are expected to further expand the problem space while drug research and development remain expensive. However, preclinical costs can be substantially mitigated by substituting animal models with in vitro devices that accurately model human cardiovascular transport. Here we present a novel physiologically relevant lab-on-a-brane that simulates in vivo pressure, flow, strain, and shear waveforms associated with normal and pathological conditions in large and small blood vessels for studying molecular transport across the endothelial monolayer. The device builds upon previously demonstrated integrated microfluidic loop design by: (a) introducing nanoscale pores in the substrate membrane to enable transmembrane molecular transport, (b) transforming the substrate membrane into a nanofibrous matrix for 3D smooth muscle cell (SMC) tissue culture, (c) integrating electrospinning fabrication methods, (d) engineering an invertible sandwich cell culture device architecture, and (e) devising a healthy co-culture mechanism for human arterial endothelial cell (HAEC) monolayer and multiple layers of human smooth muscle cells (HSMC) to accurately mimic arterial anatomy. Structural and mechanical characterization was conducted using confocal microscopy, SEM, stress/strain analysis, and infrared spectroscopy. Transport was characterized using FITC-Dextran hydraulic permeability protocol. Structure and transport characterization successfully demonstrate device viability as a physiologically relevant arterial mimic for testing transendothelial transport. Thus, our lab-on-a-brane provides a highly effective and efficient, yet considerably inexpensive, physiologically relevant alternative for pharmacokinetic evaluation; possibly reducing animals used in pre-clinical testing, clinical trials cost from false starts, and time-to-market. Furthermore, this platform can be easily configured for testing targeted therapeutic delivery and in multiple simultaneous arrays for personalized and precision medicine applications.
Database integration for investigative data visualization with the Temporal Analysis System
NASA Astrophysics Data System (ADS)
Barth, Stephen W.
1997-02-01
This paper describes an effort to provide mechanisms for integration of existing law enforcement databases with the temporal analysis system (TAS) -- an application for analysis and visualization of military intelligence data. Such integration mechanisms are essential for bringing advanced military intelligence data handling software applications to bear on the analysis of data used in criminal investigations. Our approach involved applying a software application for intelligence message handling to the problem of data base conversion. This application provides mechanisms for distributed processing and delivery of converted data records to an end-user application. It also provides a flexible graphic user interface for development and customization in the field.
An integrative process model of leadership: examining loci, mechanisms, and event cycles.
Eberly, Marion B; Johnson, Michael D; Hernandez, Morela; Avolio, Bruce J
2013-09-01
Utilizing the locus (source) and mechanism (transmission) of leadership framework (Hernandez, Eberly, Avolio, & Johnson, 2011), we propose and examine the application of an integrative process model of leadership to help determine the psychological interactive processes that constitute leadership. In particular, we identify the various dynamics involved in generating leadership processes by modeling how the loci and mechanisms interact through a series of leadership event cycles. We discuss the major implications of this model for advancing an integrative understanding of what constitutes leadership and its current and future impact on the field of psychological theory, research, and practice. © 2013 APA, all rights reserved.
48 CFR 352.234-2 - Notice of earned value management system-post-award Integrated Baseline Review.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Notice of earned value management system-post-award Integrated Baseline Review. 352.234-2 Section 352.234-2 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Texts of Provisions and Clauses 352.234...
48 CFR 352.234-1 - Notice of earned value management system-pre-award Integrated Baseline Review.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Notice of earned value management system-pre-award Integrated Baseline Review. 352.234-1 Section 352.234-1 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Texts of Provisions and Clauses 352.234-...
Kwon, Taejoon; Choi, Hyungwon; Vogel, Christine; Nesvizhskii, Alexey I; Marcotte, Edward M
2011-07-01
Shotgun proteomics using mass spectrometry is a powerful method for protein identification but suffers limited sensitivity in complex samples. Integrating peptide identifications from multiple database search engines is a promising strategy to increase the number of peptide identifications and reduce the volume of unassigned tandem mass spectra. Existing methods pool statistical significance scores such as p-values or posterior probabilities of peptide-spectrum matches (PSMs) from multiple search engines after high scoring peptides have been assigned to spectra, but these methods lack reliable control of identification error rates as data are integrated from different search engines. We developed a statistically coherent method for integrative analysis, termed MSblender. MSblender converts raw search scores from search engines into a probability score for every possible PSM and properly accounts for the correlation between search scores. The method reliably estimates false discovery rates and identifies more PSMs than any single search engine at the same false discovery rate. Increased identifications increment spectral counts for most proteins and allow quantification of proteins that would not have been quantified by individual search engines. We also demonstrate that enhanced quantification contributes to improve sensitivity in differential expression analyses.
Kwon, Taejoon; Choi, Hyungwon; Vogel, Christine; Nesvizhskii, Alexey I.; Marcotte, Edward M.
2011-01-01
Shotgun proteomics using mass spectrometry is a powerful method for protein identification but suffers limited sensitivity in complex samples. Integrating peptide identifications from multiple database search engines is a promising strategy to increase the number of peptide identifications and reduce the volume of unassigned tandem mass spectra. Existing methods pool statistical significance scores such as p-values or posterior probabilities of peptide-spectrum matches (PSMs) from multiple search engines after high scoring peptides have been assigned to spectra, but these methods lack reliable control of identification error rates as data are integrated from different search engines. We developed a statistically coherent method for integrative analysis, termed MSblender. MSblender converts raw search scores from search engines into a probability score for all possible PSMs and properly accounts for the correlation between search scores. The method reliably estimates false discovery rates and identifies more PSMs than any single search engine at the same false discovery rate. Increased identifications increment spectral counts for all detected proteins and allow quantification of proteins that would not have been quantified by individual search engines. We also demonstrate that enhanced quantification contributes to improve sensitivity in differential expression analyses. PMID:21488652
40 CFR 147.3107 - Mechanical integrity.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Oklahoma Indian Tribes § 147.3107 Mechanical integrity. (a) Monitoring of annulus pressure conducted pursuant to § 146.8(b)(1) shall be preceded by an initial pressure test. A positive gauge pressure on the casing/tubing annulus (filled with liquid) shall be maintained continuously. The pressure shall be...
40 CFR 147.3107 - Mechanical integrity.
Code of Federal Regulations, 2013 CFR
2013-07-01
... Oklahoma Indian Tribes § 147.3107 Mechanical integrity. (a) Monitoring of annulus pressure conducted pursuant to § 146.8(b)(1) shall be preceded by an initial pressure test. A positive gauge pressure on the casing/tubing annulus (filled with liquid) shall be maintained continuously. The pressure shall be...
40 CFR 147.3107 - Mechanical integrity.
Code of Federal Regulations, 2014 CFR
2014-07-01
... Oklahoma Indian Tribes § 147.3107 Mechanical integrity. (a) Monitoring of annulus pressure conducted pursuant to § 146.8(b)(1) shall be preceded by an initial pressure test. A positive gauge pressure on the casing/tubing annulus (filled with liquid) shall be maintained continuously. The pressure shall be...
40 CFR 147.3107 - Mechanical integrity.
Code of Federal Regulations, 2012 CFR
2012-07-01
... Oklahoma Indian Tribes § 147.3107 Mechanical integrity. (a) Monitoring of annulus pressure conducted pursuant to § 146.8(b)(1) shall be preceded by an initial pressure test. A positive gauge pressure on the casing/tubing annulus (filled with liquid) shall be maintained continuously. The pressure shall be...
Identification of candidate genes in osteoporosis by integrated microarray analysis.
Li, J J; Wang, B Q; Fei, Q; Yang, Y; Li, D
2016-12-01
In order to screen the altered gene expression profile in peripheral blood mononuclear cells of patients with osteoporosis, we performed an integrated analysis of the online microarray studies of osteoporosis. We searched the Gene Expression Omnibus (GEO) database for microarray studies of peripheral blood mononuclear cells in patients with osteoporosis. Subsequently, we integrated gene expression data sets from multiple microarray studies to obtain differentially expressed genes (DEGs) between patients with osteoporosis and normal controls. Gene function analysis was performed to uncover the functions of identified DEGs. A total of three microarray studies were selected for integrated analysis. In all, 1125 genes were found to be significantly differentially expressed between osteoporosis patients and normal controls, with 373 upregulated and 752 downregulated genes. Positive regulation of the cellular amino metabolic process (gene ontology (GO): 0033240, false discovery rate (FDR) = 1.00E + 00) was significantly enriched under the GO category for biological processes, while for molecular functions, flavin adenine dinucleotide binding (GO: 0050660, FDR = 3.66E-01) and androgen receptor binding (GO: 0050681, FDR = 6.35E-01) were significantly enriched. DEGs were enriched in many osteoporosis-related signalling pathways, including those of mitogen-activated protein kinase (MAPK) and calcium. Protein-protein interaction (PPI) network analysis showed that the significant hub proteins contained ubiquitin specific peptidase 9, X-linked (Degree = 99), ubiquitin specific peptidase 19 (Degree = 57) and ubiquitin conjugating enzyme E2 B (Degree = 57). Analysis of gene function of identified differentially expressed genes may expand our understanding of fundamental mechanisms leading to osteoporosis. Moreover, significantly enriched pathways, such as MAPK and calcium, may involve in osteoporosis through osteoblastic differentiation and bone formation.Cite this article: J. J. Li, B. Q. Wang, Q. Fei, Y. Yang, D. Li. Identification of candidate genes in osteoporosis by integrated microarray analysis. Bone Joint Res 2016;5:594-601. DOI: 10.1302/2046-3758.512.BJR-2016-0073.R1. © 2016 Fei et al.
Opportunities for and constraints to integration of health services in Poland*
Sobczak, Alicja
2002-01-01
Abstract At the beginning of the article the typologies, expected outcomes and forces aiming at health care integration are discussed. Integration is recognised as a multidimensional concept. The suggested typologies of integration are based on structural configurations, co-ordination mechanisms (including clinical co-ordination), and driving forces. A review of the Polish experience in integration/disintegration of health care systems is the main part of the article. Creation of integrated health care management units (ZOZs) in the beginning of the 1970s serves as an example of structural vertical integration missing co-ordination mechanisms. ZOZs as huge, costly and inflexible organisations became subjects of public criticism and discredited the idea of health care integration. At the end of the 1980s and in the decade of the 1990s, management of public health care was decentralised, the majority of ZOZs dismantled, and many health care public providers got the status of independent entities. The private sector developed rapidly. Sickness funds, which in 1999 replaced the previous state system, introduced “quasi-market” conditions where health providers have to compete for contracts. Some providers developed strategies of vertical and horizontal integration to get a competitive advantage. Consolidation of private ambulatory clinics, the idea of “integrated care” as a “contracting package”, development of primary health care and ambulatory specialist clinics in hospitals are the examples of such strategies. The new health policy declared in 2002 has recognised integration as a priority. It stresses the development of payment mechanisms and information base (Register of Health Services – RUM) that promote integration. The Ministry of Health is involved directly in integrated emergency system designing. It seems that after years of disintegration and deregulation the need for effective integration has become obvious. PMID:16896398
DOE Office of Scientific and Technical Information (OSTI.GOV)
Tanizaki, Yuya, E-mail: yuya.tanizaki@riken.jp; Theoretical Research Division, Nishina Center, RIKEN, Wako 351-0198; Koike, Takayuki, E-mail: tkoike@ms.u-tokyo.ac.jp
Picard–Lefschetz theory is applied to path integrals of quantum mechanics, in order to compute real-time dynamics directly. After discussing basic properties of real-time path integrals on Lefschetz thimbles, we demonstrate its computational method in a concrete way by solving three simple examples of quantum mechanics. It is applied to quantum mechanics of a double-well potential, and quantum tunneling is discussed. We identify all of the complex saddle points of the classical action, and their properties are discussed in detail. However a big theoretical difficulty turns out to appear in rewriting the original path integral into a sum of path integralsmore » on Lefschetz thimbles. We discuss generality of that problem and mention its importance. Real-time tunneling processes are shown to be described by those complex saddle points, and thus semi-classical description of real-time quantum tunneling becomes possible on solid ground if we could solve that problem. - Highlights: • Real-time path integral is studied based on Picard–Lefschetz theory. • Lucid demonstration is given through simple examples of quantum mechanics. • This technique is applied to quantum mechanics of the double-well potential. • Difficulty for practical applications is revealed, and we discuss its generality. • Quantum tunneling is shown to be closely related to complex classical solutions.« less
Weis, Jared A.; Granero-Moltó, Froilán; Myers, Timothy J.; Longobardi, Lara; Spagnoli, Anna; Miga, Michael I.
2013-01-01
An important concern in the study of fracture healing is the ability to assess mechanical integrity in response to candidate therapeutics in small-animal systems. In recent reports, it has been proposed that microCT image-derived densitometric parameters could be used as a surrogate for mechanical property assessment. Recently, we have proposed an inverse methodology that iteratively reconstructs the modulus of elasticity of the lumped soft callus/hard callus region by integrating both intrinsic mechanical property (from biomechanical testing) and geometrical information (from microCT) within an inverse finite element analysis (FEA) to define a callus quality measure. In this paper, data from a therapeutic system involving mesenchymal stem cells is analyzed within the context of comparing traditional microCT densitometric and mechanical property metrics. In addition, a novel multi-parameter regression microCT parameter is analyzed as well as our inverse FEA metric. The results demonstrate that the inverse FEA approach was the only metric to successfully detect both longitudinal and therapeutic responses. While the most promising microCT-based metrics were adequate at early healing states, they failed to track late-stage mechanical integrity. In addition, our analysis added insight to the role of MSCs by demonstrating accelerated healing and was the only metric to demonstrate therapeutic benefits at late-stage healing. In conclusion, the work presented here indicates that microCT densitometric parameters are an incomplete surrogate for mechanical integrity. Additionally, our inverse FEA approach is shown to be very sensitive and may provide a first-step towards normalizing the often challenging process of assessing mechanical integrity of healing fractures. PMID:22766379
47 CFR 54.602 - Health care support mechanism.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 47 Telecommunication 3 2013-10-01 2013-10-01 false Health care support mechanism. 54.602 Section... (CONTINUED) UNIVERSAL SERVICE Universal Service Support for Health Care Providers Defined Terms and Eligibility § 54.602 Health care support mechanism. (a) Telecommunications Program. Rural health care...
30 CFR 56.19008 - Friction hoist synchronizing mechanisms.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Friction hoist synchronizing mechanisms. 56... Personnel Hoisting Hoists § 56.19008 Friction hoist synchronizing mechanisms. Where creep or slip may alter the effective position of safety devices, friction hoists shall be equipped with synchronizing...
30 CFR 57.19008 - Friction hoist synchronizing mechanisms.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Friction hoist synchronizing mechanisms. 57... MINES Personnel Hoisting Hoists § 57.19008 Friction hoist synchronizing mechanisms. Where creep or slip may alter the effective position of safety devices, friction hoists shall be equipped with...
30 CFR 57.19008 - Friction hoist synchronizing mechanisms.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Friction hoist synchronizing mechanisms. 57... MINES Personnel Hoisting Hoists § 57.19008 Friction hoist synchronizing mechanisms. Where creep or slip may alter the effective position of safety devices, friction hoists shall be equipped with...
30 CFR 57.19008 - Friction hoist synchronizing mechanisms.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Friction hoist synchronizing mechanisms. 57... MINES Personnel Hoisting Hoists § 57.19008 Friction hoist synchronizing mechanisms. Where creep or slip may alter the effective position of safety devices, friction hoists shall be equipped with...
30 CFR 56.19008 - Friction hoist synchronizing mechanisms.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Friction hoist synchronizing mechanisms. 56... Personnel Hoisting Hoists § 56.19008 Friction hoist synchronizing mechanisms. Where creep or slip may alter the effective position of safety devices, friction hoists shall be equipped with synchronizing...
30 CFR 56.19008 - Friction hoist synchronizing mechanisms.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Friction hoist synchronizing mechanisms. 56... Personnel Hoisting Hoists § 56.19008 Friction hoist synchronizing mechanisms. Where creep or slip may alter the effective position of safety devices, friction hoists shall be equipped with synchronizing...
30 CFR 57.19008 - Friction hoist synchronizing mechanisms.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Friction hoist synchronizing mechanisms. 57... MINES Personnel Hoisting Hoists § 57.19008 Friction hoist synchronizing mechanisms. Where creep or slip may alter the effective position of safety devices, friction hoists shall be equipped with...
30 CFR 56.19008 - Friction hoist synchronizing mechanisms.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Friction hoist synchronizing mechanisms. 56... Personnel Hoisting Hoists § 56.19008 Friction hoist synchronizing mechanisms. Where creep or slip may alter the effective position of safety devices, friction hoists shall be equipped with synchronizing...
30 CFR 75.1722 - Mechanical equipment guards.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Mechanical equipment guards. 75.1722 Section 75.1722 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Miscellaneous § 75.1722 Mechanical equipment...
21 CFR 890.3850 - Mechanical wheelchair.
Code of Federal Regulations, 2013 CFR
2013-04-01
... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Mechanical wheelchair. 890.3850 Section 890.3850 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES PHYSICAL MEDICINE DEVICES Physical Medicine Prosthetic Devices § 890.3850 Mechanical...
21 CFR 890.3850 - Mechanical wheelchair.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Mechanical wheelchair. 890.3850 Section 890.3850 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES PHYSICAL MEDICINE DEVICES Physical Medicine Prosthetic Devices § 890.3850 Mechanical...
21 CFR 890.3850 - Mechanical wheelchair.
Code of Federal Regulations, 2014 CFR
2014-04-01
... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Mechanical wheelchair. 890.3850 Section 890.3850 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES PHYSICAL MEDICINE DEVICES Physical Medicine Prosthetic Devices § 890.3850 Mechanical...
21 CFR 890.3850 - Mechanical wheelchair.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Mechanical wheelchair. 890.3850 Section 890.3850 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES PHYSICAL MEDICINE DEVICES Physical Medicine Prosthetic Devices § 890.3850 Mechanical...
21 CFR 890.3850 - Mechanical wheelchair.
Code of Federal Regulations, 2012 CFR
2012-04-01
... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Mechanical wheelchair. 890.3850 Section 890.3850 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES PHYSICAL MEDICINE DEVICES Physical Medicine Prosthetic Devices § 890.3850 Mechanical...
30 CFR 56.19008 - Friction hoist synchronizing mechanisms.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Friction hoist synchronizing mechanisms. 56... Personnel Hoisting Hoists § 56.19008 Friction hoist synchronizing mechanisms. Where creep or slip may alter the effective position of safety devices, friction hoists shall be equipped with synchronizing...
30 CFR 57.19008 - Friction hoist synchronizing mechanisms.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Friction hoist synchronizing mechanisms. 57... MINES Personnel Hoisting Hoists § 57.19008 Friction hoist synchronizing mechanisms. Where creep or slip may alter the effective position of safety devices, friction hoists shall be equipped with...
46 CFR 160.033-3 - Construction of mechanical disengaging apparatus.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 46 Shipping 6 2011-10-01 2011-10-01 false Construction of mechanical disengaging apparatus. 160.033-3 Section 160.033-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Mechanical Disengaging Apparatus...
29 CFR 1926.307 - Mechanical power-transmission apparatus.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 29 Labor 8 2011-07-01 2011-07-01 false Mechanical power-transmission apparatus. 1926.307 Section....307 Mechanical power-transmission apparatus. (a) General requirements. (1) This section covers all... keyways shall be filled up or covered. (5) Power-transmission apparatus located in basements. All...
46 CFR 160.033-3 - Construction of mechanical disengaging apparatus.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 46 Shipping 6 2010-10-01 2010-10-01 false Construction of mechanical disengaging apparatus. 160.033-3 Section 160.033-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT, CONSTRUCTION, AND MATERIALS: SPECIFICATIONS AND APPROVAL LIFESAVING EQUIPMENT Mechanical Disengaging Apparatus...
29 CFR 1926.307 - Mechanical power-transmission apparatus.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 29 Labor 8 2010-07-01 2010-07-01 false Mechanical power-transmission apparatus. 1926.307 Section....307 Mechanical power-transmission apparatus. (a) General requirements. (1) This section covers all... keyways shall be filled up or covered. (5) Power-transmission apparatus located in basements. All...
Structural Integrity Of Low-Velocity Impacted C/SIC Ceramic Matrix Composites
NASA Astrophysics Data System (ADS)
Knoche, R.; Drose, A.
2012-07-01
Carbon fibre reinforced silicon carbide (C/SiC) ceramic matrix composites (CMC) are most favourable for thermal protection systems & hot structures in re-entry vehicles since they offer superior heat resistance, high specific strength as well as a low coefficient of temperature expansion (CTE). To ensure the structural integrity of these C/SiC structures and thus mission safety all potential degradation effects during manufacturing and lifetime have to be considered. One of the most probable defects which may harm the structural integrity significantly can be caused by low-velocity impacts (LVI) which may occur during transportation and integration by e.g. dropping of tools. Thus the present study focuses on the residual mechanical and thermo-mechanical performance of C/SiC composites after being exposed to a low-velocity impact in terms of initial and residual mechanical performance, changes in microstructure, as well as thermo-mechanical performance through exposing specimens to multiple experimentally simulated re-entries. The results reveal the impact characteristics and damage mechanisms of C/SiC CMC exposed to a low-velocity impact and evidence the functional reliability as well as the damage tolerance of the C/SiC material investigated.
Martin, Andrea E.
2016-01-01
I argue that cue integration, a psychophysiological mechanism from vision and multisensory perception, offers a computational linking hypothesis between psycholinguistic theory and neurobiological models of language. I propose that this mechanism, which incorporates probabilistic estimates of a cue's reliability, might function in language processing from the perception of a phoneme to the comprehension of a phrase structure. I briefly consider the implications of the cue integration hypothesis for an integrated theory of language that includes acquisition, production, dialogue and bilingualism, while grounding the hypothesis in canonical neural computation. PMID:26909051
Temporal resolution for the perception of features and conjunctions.
Bodelón, Clara; Fallah, Mazyar; Reynolds, John H
2007-01-24
The visual system decomposes stimuli into their constituent features, represented by neurons with different feature selectivities. How the signals carried by these feature-selective neurons are integrated into coherent object representations is unknown. To constrain the set of possible integrative mechanisms, we quantified the temporal resolution of perception for color, orientation, and conjunctions of these two features. We find that temporal resolution is measurably higher for each feature than for their conjunction, indicating that time is required to integrate features into a perceptual whole. This finding places temporal limits on the mechanisms that could mediate this form of perceptual integration.
40 CFR 144.52 - Establishing permit conditions.
Code of Federal Regulations, 2010 CFR
2010-07-01
... comply with the financial responsibility requirements of subpart F of this part. (8) Mechanical integrity. A permit for any Class I, II or III well or injection project which lacks mechanical integrity shall... Administrator. (6) After a cessation of operations of two years the owner or operator shall plug and abandon the...
Teaching Basic Quantum Mechanics in Secondary School Using Concepts of Feynman Path Integrals Method
ERIC Educational Resources Information Center
Fanaro, Maria de los Angeles; Otero, Maria Rita; Arlego, Marcelo
2012-01-01
This paper discusses the teaching of basic quantum mechanics in high school. Rather than following the usual formalism, our approach is based on Feynman's path integral method. Our presentation makes use of simulation software and avoids sophisticated mathematical formalism. (Contains 3 figures.)
DOT National Transportation Integrated Search
2017-02-02
At present, there is a need to assess the mechanical integrity and sustainability of pre-stressed concrete beams during the entire life cycle of the built infrastructure. According to the NCHRP (Tadros et al., 2010), further research to develop fi...
High Gain Antenna System Deployment Mechanism Integration, Characterization, and Lessons Learned
NASA Technical Reports Server (NTRS)
Parong, Fil; Russell, Blair; Garcen, Walter; Rose, Chris; Johnson, Chris; Huber, Craig
2014-01-01
The integration and deployment testing of the High Gain Antenna System (HGAS) for the Global Precipitation Measurement mission is summarized. The HGAS deployment mechanism is described. The gravity negation system configuration and its influence on vertical, ground-based deployment tests are presented with test data and model predictions. A focus is made on the late discovery and resolution of a potentially mission-degrading deployment interference condition. The interaction of the flight deployment mechanism, gravity-negation mechanism, and use of dynamic modeling is described and lessons learned presented
High Gain Antenna System Deployment Mechanism Integration, Characterization, and Lessons Learned
NASA Technical Reports Server (NTRS)
Parong, Fil; Russell, Blair; Garcen, Walter; Rose, Chris; Johnson, Chris; Huber, Craig
2014-01-01
The integration and deployment testing of the High Gain Antenna System for the Global Precipitation Measurement mission is summarized. The HGAS deployment mechanism is described. The gravity negation system configuration and its influence on vertical, ground-based, deployment tests are presented with test data and model predictions. A focus is made on the late discovery and resolution of a potentially mission degrading deployment interference condition. The interaction of the flight deployment mechanism, gravity negation mechanism, and use of dynamic modeling is described and lessons learned presented.
Strategies for the evaluation of DNA damage and repair mechanisms in cancer.
Figueroa-González, Gabriela; Pérez-Plasencia, Carlos
2017-06-01
DNA lesions and the repair mechanisms that maintain the integrity of genomic DNA are important in preventing carcinogenesis and its progression. Notably, mutations in DNA repair mechanisms are associated with cancer predisposition syndromes. Additionally, these mechanisms maintain the genomic integrity of cancer cells. The majority of therapies established to treat cancer are genotoxic agents that induce DNA damage, promoting cancer cells to undergo apoptotic death. Effective methods currently exist to evaluate the diverse effects of genotoxic agents and the underlying molecular mechanisms that repair DNA lesions. The current study provides an overview of a number of methods that are available for the detection, analysis and quantification of underlying DNA repair mechanisms.
46 CFR 154.506 - Mechanical expansion joint: Limits in a piping system.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 46 Shipping 5 2013-10-01 2013-10-01 false Mechanical expansion joint: Limits in a piping system..., Construction and Equipment Cargo and Process Piping Systems § 154.506 Mechanical expansion joint: Limits in a piping system. Mechanical expansion joints in a piping system outside of a cargo tank: (a) May be...
46 CFR 154.506 - Mechanical expansion joint: Limits in a piping system.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 46 Shipping 5 2014-10-01 2014-10-01 false Mechanical expansion joint: Limits in a piping system..., Construction and Equipment Cargo and Process Piping Systems § 154.506 Mechanical expansion joint: Limits in a piping system. Mechanical expansion joints in a piping system outside of a cargo tank: (a) May be...
46 CFR 154.506 - Mechanical expansion joint: Limits in a piping system.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 46 Shipping 5 2011-10-01 2011-10-01 false Mechanical expansion joint: Limits in a piping system..., Construction and Equipment Cargo and Process Piping Systems § 154.506 Mechanical expansion joint: Limits in a piping system. Mechanical expansion joints in a piping system outside of a cargo tank: (a) May be...
46 CFR 154.506 - Mechanical expansion joint: Limits in a piping system.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 46 Shipping 5 2012-10-01 2012-10-01 false Mechanical expansion joint: Limits in a piping system..., Construction and Equipment Cargo and Process Piping Systems § 154.506 Mechanical expansion joint: Limits in a piping system. Mechanical expansion joints in a piping system outside of a cargo tank: (a) May be...
46 CFR 12.15-13 - Deck engine mechanic.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 46 Shipping 1 2010-10-01 2010-10-01 false Deck engine mechanic. 12.15-13 Section 12.15-13 Shipping... ENDORSEMENTS Qualified Member of the Engine Department § 12.15-13 Deck engine mechanic. (a) An applicant for an endorsement as deck engine mechanic shall be a person holding an MMC or MMD endorsed as junior engineer. The...
46 CFR 12.15-13 - Deck engine mechanic.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 46 Shipping 1 2012-10-01 2012-10-01 false Deck engine mechanic. 12.15-13 Section 12.15-13 Shipping... ENDORSEMENTS Qualified Member of the Engine Department § 12.15-13 Deck engine mechanic. (a) An applicant for an endorsement as deck engine mechanic shall be a person holding an MMC or MMD endorsed as junior engineer. The...
46 CFR 12.15-13 - Deck engine mechanic.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 46 Shipping 1 2013-10-01 2013-10-01 false Deck engine mechanic. 12.15-13 Section 12.15-13 Shipping... ENDORSEMENTS Qualified Member of the Engine Department § 12.15-13 Deck engine mechanic. (a) An applicant for an endorsement as deck engine mechanic shall be a person holding an MMC or MMD endorsed as junior engineer. The...
46 CFR 12.15-13 - Deck engine mechanic.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 46 Shipping 1 2011-10-01 2011-10-01 false Deck engine mechanic. 12.15-13 Section 12.15-13 Shipping... ENDORSEMENTS Qualified Member of the Engine Department § 12.15-13 Deck engine mechanic. (a) An applicant for an endorsement as deck engine mechanic shall be a person holding an MMC or MMD endorsed as junior engineer. The...
46 CFR 154.506 - Mechanical expansion joint: Limits in a piping system.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 46 Shipping 5 2010-10-01 2010-10-01 false Mechanical expansion joint: Limits in a piping system..., Construction and Equipment Cargo and Process Piping Systems § 154.506 Mechanical expansion joint: Limits in a piping system. Mechanical expansion joints in a piping system outside of a cargo tank: (a) May be...
49 CFR 234.255 - Gate arm and gate mechanism.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 49 Transportation 4 2010-10-01 2010-10-01 false Gate arm and gate mechanism. 234.255 Section 234... Maintenance, Inspection, and Testing Inspections and Tests § 234.255 Gate arm and gate mechanism. (a) Each gate arm and gate mechanism shall be inspected at least once each month. (b) Gate arm movement shall be...
49 CFR 234.255 - Gate arm and gate mechanism.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 49 Transportation 4 2011-10-01 2011-10-01 false Gate arm and gate mechanism. 234.255 Section 234... Maintenance, Inspection, and Testing Inspections and Tests § 234.255 Gate arm and gate mechanism. (a) Each gate arm and gate mechanism shall be inspected at least once each month. (b) Gate arm movement shall be...
49 CFR 234.255 - Gate arm and gate mechanism.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 49 Transportation 4 2013-10-01 2013-10-01 false Gate arm and gate mechanism. 234.255 Section 234....255 Gate arm and gate mechanism. (a) Each gate arm and gate mechanism shall be inspected at least once each month. (b) Gate arm movement shall be observed for proper operation at least once each month. (c...
49 CFR 234.255 - Gate arm and gate mechanism.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 49 Transportation 4 2014-10-01 2014-10-01 false Gate arm and gate mechanism. 234.255 Section 234....255 Gate arm and gate mechanism. (a) Each gate arm and gate mechanism shall be inspected at least once each month. (b) Gate arm movement shall be observed for proper operation at least once each month. (c...
49 CFR 234.255 - Gate arm and gate mechanism.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 49 Transportation 4 2012-10-01 2012-10-01 false Gate arm and gate mechanism. 234.255 Section 234....255 Gate arm and gate mechanism. (a) Each gate arm and gate mechanism shall be inspected at least once each month. (b) Gate arm movement shall be observed for proper operation at least once each month. (c...
76 FR 55402 - Center for Scientific Review; Notice of Closed Meetings
Federal Register 2010, 2011, 2012, 2013, 2014
2011-09-07
... Committee: Integrative, Functional and Cognitive Neuroscience Integrated Review Group, Neurobiology [email protected] . Name of Committee: Integrative, Functional and Cognitive Neuroscience Integrated Review Group, Mechanisms of Sensory, Perceptual, and Cognitive Processes Study Section. Date: October 11-12...
10 CFR 900.4 - Pre-Application mechanism.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 10 Energy 4 2010-01-01 2010-01-01 false Pre-Application mechanism. 900.4 Section 900.4 Energy DEPARTMENT OF ENERGY COORDINATION OF FEDERAL AUTHORIZATIONS FOR ELECTRIC TRANSMISSION FACILITIES § 900.4 Pre-Application mechanism. (a) An applicant, or prospective applicant, for a Federal authorization seeking...
21 CFR 890.3825 - Mechanical walker.
Code of Federal Regulations, 2014 CFR
2014-04-01
... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Mechanical walker. 890.3825 Section 890.3825 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES PHYSICAL MEDICINE DEVICES Physical Medicine Prosthetic Devices § 890.3825 Mechanical walker. (a...