Innovative Technologies And Modern Facilities In Beekeeping

NASA Astrophysics Data System (ADS)

Gaga, V. A.; Esaulov, V. N.

2016-08-01

This article discusses the features of the application of innovative technologies in beekeeping. The authors, based on years of personal experience in beekeeping and learning experience of the best apiaries in Russia and abroad, summarized materials on the topic and offered advanced modern technology in beekeeping to apply, which was successfully tested in other apiaries.

Exploring Some Design Principles for Tutoring in Preservice Teacher Preparation

ERIC Educational Resources Information Center

Hoffman, James V.; Mosley Wetzel, Melissa

2017-01-01

In this article we summarize our research into literacy preservice teacher preparation. We situate our research on tutorials in the practice turn in teacher preparation. We describe the evolution of our work drawing on findings from seven different studies with the goal of identifying the design features of tutorial experiences that promote…

Biomolecules in the Computer: Jmol to the Rescue

ERIC Educational Resources Information Center

Herraez, Angel

2006-01-01

Jmol is free, open source software for interactive molecular visualization. Since it is written in the Java[TM] programming language, it is compatible with all major operating systems and, in the applet form, with most modern web browsers. This article summarizes Jmol development and features that make it a valid and promising replacement for…

Maximizing Access Technology Tools for the Library of the Future

ERIC Educational Resources Information Center

Pearson, Waynn

2003-01-01

The renovated Cerritos Public Library is a unique blending of traditional and hightech features. One of the key principles in its planning and design was to enable a range of convenient access services. This article summarizes the process of building this library and how it has been received by users. (Contains 5 figures.)

Phyllotaxis: Some progress, but a story far from over

NASA Astrophysics Data System (ADS)

Pennybacker, Matthew F.; Shipman, Patrick D.; Newell, Alan C.

2015-06-01

This is a review article with a point of view. We summarize the long history of the subject and recent advances and suggest that almost all features of the architecture of shoot apical meristems can be captured by pattern-forming systems which model the biochemistry and biophysics of those regions on plants.

Across the Board: Nam-Gyu Park.

PubMed

Park, Nam-Gyu

2016-09-22

In this series of articles, the board members of ChemSusChem discuss recent research articles that they consider of exceptional quality and importance for sustainability. This entry features Prof. Nam-Gyu Park, who highlights the recent work on mixed-cation mixed-anion perovskite materials toward high efficiency perovskite solar cells. He summarizes the work that has brought us to the current stage of research and suggests possible future paths for further advancement. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Insights into How Students Learn the Difference between a Weak Acid and a Strong Acid from Cartoon Tutorials Employing Visualizations

ERIC Educational Resources Information Center

Kelly, Resa M.; Akaygun, Sevil

2016-01-01

This article summarizes an investigation into how Flash-based cartoon video tutorials featuring molecular visualizations affect students' mental models of acetic acid and hydrochloric acid solutions and how the acids respond when tested for electrical conductance. Variation theory served as the theoretical framework for examining how students…

An Assessment of Agriculture and Natural Resource Extension Program Needs on American Indian Reservations in Idaho, Nevada, Oregon, and Washington

ERIC Educational Resources Information Center

Singletary, Loretta; Emm, Staci; Hill, George

2011-01-01

This article summarizes the results of a needs assessment involving American Indians and outreach professionals on reservations in Idaho, Nevada, Oregon and Washington. The survey featured 36 questions about agricultural and natural resource issues that may pose challenges on reservation lands. A comparison between reservation residents and…

The Diagnosis and Understanding of Apraxia of Speech: Why Including Neurodegenerative Etiologies May Be Important

ERIC Educational Resources Information Center

Duffy, Joseph R.; Josephs, Keith A.

2012-01-01

Purpose: To discuss apraxia of speech (AOS) as it occurs in neurodegenerative disease (progressive AOS [PAOS]) and how its careful study may contribute to general concepts of AOS and help refine its diagnostic criteria. Method: The article summarizes our current understanding of the clinical features and neuroanatomical and pathologic correlates…

Measuring the Impacts of a Volunteer-Based Community Development Program in Developing Volunteers' Leadership Skills

ERIC Educational Resources Information Center

Meier, Amy; Singletary, Loretta; Hill, George

2012-01-01

This article summarizes the results of an evaluation of the impacts of a community development program to develop leadership skills in its adult volunteers. The evaluation featured 20 questions about leadership skills learned as a result of volunteer experiences. Data analysis strategies beyond a simple means ranking resulted in evidence…

Visualizing Article Similarities via Sparsified Article Network and Map Projection for Systematic Reviews.

PubMed

Ji, Xiaonan; Machiraju, Raghu; Ritter, Alan; Yen, Po-Yin

2017-01-01

Systematic Reviews (SRs) of biomedical literature summarize evidence from high-quality studies to inform clinical decisions, but are time and labor intensive due to the large number of article collections. Article similarities established from textual features have been shown to assist in the identification of relevant articles, thus facilitating the article screening process efficiently. In this study, we visualized article similarities to extend its utilization in practical settings for SR researchers, aiming to promote human comprehension of article distributions and hidden patterns. To prompt an effective visualization in an interpretable, intuitive, and scalable way, we implemented a graph-based network visualization with three network sparsification approaches and a distance-based map projection via dimensionality reduction. We evaluated and compared three network sparsification approaches and the visualization types (article network vs. article map). We demonstrated the effectiveness in revealing article distribution and exhibiting clustering patterns of relevant articles with practical meanings for SRs.

Implementing and Integrating Effective Teaching Strategies Including Features of Lesson Study in an Elementary Science Methods Course

ERIC Educational Resources Information Center

Carrier, Sarah J.

2011-01-01

Teacher preparation programs have been under attack by policy makers in the last decade, and teacher educators are constantly striving to improve their programs. Yet, there are several research-based practices that have been shown to be effective for developing teachers. In this article, the author summarizes a study in one science methods course…

Survey of natural products reported by Asian research groups in 2016.

PubMed

Liu, Yan-Fei; Yu, Shi-Shan

2017-11-01

The new natural products reported in peer-reviewed articles in 2016 in journals with good reputations were reviewed and analyzed. The advances that Asian research groups made in the field of natural products chemistry in 2016 were summarized. Compounds with unique structural features and/or promising bioactivities originating from Asian natural sources were discussed based on structural classification.

Le "Quadrille": de la lecture des journaux a l'expression orale (The "Quadrille": From Newspaper Reading to Oral Expression).

ERIC Educational Resources Information Center

Levy, Francine

1990-01-01

In an activity for the French classroom, teams of four student pairs read and summarize newspaper and magazine articles, extract a vocabulary list, prepare content questions, and become experts on portions of the text for a small-group discussion game. Changing partners and solo presentation are important features of the exercise. (MSE)

Polymer-Nanoparticle Composites: From Synthesis to Modern Applications

PubMed Central

Hanemann, Thomas; Szabó, Dorothée Vinga

2010-01-01

The addition of inorganic spherical nanoparticles to polymers allows the modification of the polymers physical properties as well as the implementation of new features in the polymer matrix. This review article covers considerations on special features of inorganic nanoparticles, the most important synthesis methods for ceramic nanoparticles and nanocomposites, nanoparticle surface modification, and composite formation, including drawbacks. Classical nanocomposite properties, as thermomechanical, dielectric, conductive, magnetic, as well as optical properties, will be summarized. Finally, typical existing and potential applications will be shown with the focus on new and innovative applications, like in energy storage systems.

[IgG4-related disease].

PubMed

González-Moreno, Juan; Losada López, Inés; Ortego Centeno, Norberto

2015-12-21

IgG4-related disease is a recently described clinicopathological entity showing a wide spectrum of clinical manifestations that share a common pathology. Its most characteristic feature is the formation of inflammatory tumors in different organs, which makes differentiation mainly with neoplastic diseases fundamental. The inflammatory process is typically comprised of IgG4 lymphoplasmacytic cells. The pathophysiological role of the immunoglobulin is not clear. The treatment of choice is corticosteroids. This article aims to summarize the main features of the disease. Copyright © 2015 Elsevier España, S.L.U. All rights reserved.

Literary psychiatric observation and diagnosis through the ages: King Lear revisited.

PubMed

Truskinovsky, Alexander M

2002-03-01

Shakespeare's plays, and in particular King Lear, have been a favorite source of clinical observation and diagnosis for psychiatrists for the past two centuries. Most authors agree that the description of Lear's mental symptoms is remarkably consistent and close to life. This article summarizes previous attempts to diagnose the mental illness of King Lear, featuring, among others, such entities as mania, senile dementia, delirium, depression, and brief reactive psychosis, and offers a new diagnosis according to the modern diagnostic criteria, namely, bipolar I disorder, most recent episode manic, severe with psychotic features.

Review of cardiovascular imaging in The Journal of Nuclear Cardiology in 2014: Part 1 of 2: Positron emission tomography, computed tomography, and neuronal imaging.

PubMed

AlJaroudi, Wael A; Hage, Fadi G

2015-06-01

The year 2014 has been an exciting year for the cardiovascular imaging community with significant advances in the realm of nuclear and multimodality cardiac imaging. In this new feature of the Journal of Nuclear Cardiology, we will summarize some of the breakthroughs that were published in the Journal in 2014 in 2 sister articles. This first article will concentrate on publications dealing with cardiac positron emission tomography (PET), computed tomography (CT), and neuronal imaging.

Learning to rank-based gene summary extraction.

PubMed

Shang, Yue; Hao, Huihui; Wu, Jiajin; Lin, Hongfei

2014-01-01

In recent years, the biomedical literature has been growing rapidly. These articles provide a large amount of information about proteins, genes and their interactions. Reading such a huge amount of literature is a tedious task for researchers to gain knowledge about a gene. As a result, it is significant for biomedical researchers to have a quick understanding of the query concept by integrating its relevant resources. In the task of gene summary generation, we regard automatic summary as a ranking problem and apply the method of learning to rank to automatically solve this problem. This paper uses three features as a basis for sentence selection: gene ontology relevance, topic relevance and TextRank. From there, we obtain the feature weight vector using the learning to rank algorithm and predict the scores of candidate summary sentences and obtain top sentences to generate the summary. ROUGE (a toolkit for summarization of automatic evaluation) was used to evaluate the summarization result and the experimental results showed that our method outperforms the baseline techniques. According to the experimental result, the combination of three features can improve the performance of summary. The application of learning to rank can facilitate the further expansion of features for measuring the significance of sentences.

International Perspectives on Academic and Professional Preparation of School and Educational Psychologists: Introduction to a Special Issue of the "International Journal of School & Educational Psychology"

ERIC Educational Resources Information Center

Oakland, Thomas; Hatzichristou, Chryse

2014-01-01

This special issue of the "International Journal of School & Educational Psychology" is devoted to promoting an understanding of some current features of school psychology programs and to suggest ways to further strengthen preparation. Information summarized in these 12 articles is intended to assist us in determining the relevance…

Tachycardia detection in ICDs by Boston Scientific : Algorithms, pearls, and pitfalls.

PubMed

Zanker, Norbert; Schuster, Diane; Gilkerson, James; Stein, Kenneth

2016-09-01

The aim of this study was to summarize how implantable cardioverter defibrillators (ICDs) by Boston Scientific sense, detect, discriminate rhythms, and classify episodes. Modern devices include multiple programming selections, diagnostic features, therapy options, memory functions, and device-related history features. Device operation includes logical steps from sensing, detection, discrimination, therapy delivery to history recording. The program is designed to facilitate the application of the device algorithms to the individual patient's clinical needs. Features and functions described in this article represent a selective excerpt by the authors from Boston Scientific publicly available product resources. Programming of ICDs may affect patient outcomes. Patient-adapted and optimized programming requires understanding of device operation and concepts.

[Natural history of flowers and gravity].

PubMed

Yamashita, Masamichi; Tomita-Yokotani, Kaori; Nakamura, Teruko

2004-06-01

Many flowers have coevolved with their pollinator animals. Gravity has been one of selection pressure for the evolution of flowers. Gravity rules morphology and other features of flowers in many aspects. Pair matching between the flower and its specific pollinator is one of factors that determine the fitness of both sides. Evolution of flower morphology and its molecular basis are reviewed briefly. Anemophilous flowers are also under the influence of gravity. Shape and other features of entomophilous flowers have been highly diversed. Gravitropic response and its mechanism are summarized. Recent findings on gravitropism and phototropism of pistils and stamens are presented in this article.

What Defines the "Kingdom" Fungi?

PubMed

Richards, Thomas A; Leonard, Guy; Wideman, Jeremy G

2017-06-01

The application of environmental DNA techniques and increased genome sequencing of microbial diversity, combined with detailed study of cellular characters, has consistently led to the reexamination of our understanding of the tree of life. This has challenged many of the definitions of taxonomic groups, especially higher taxonomic ranks such as eukaryotic kingdoms. The Fungi is an example of a kingdom which, together with the features that define it and the taxa that are grouped within it, has been in a continual state of flux. In this article we aim to summarize multiple lines of data pertinent to understanding the early evolution and definition of the Fungi. These include ongoing cellular and genomic comparisons that, we will argue, have generally undermined all attempts to identify a synapomorphic trait that defines the Fungi. This article will also summarize ongoing work focusing on taxon discovery, combined with phylogenomic analysis, which has identified novel groups that lie proximate/adjacent to the fungal clade-wherever the boundary that defines the Fungi may be. Our hope is that, by summarizing these data in the form of a discussion, we can illustrate the ongoing efforts to understand what drove the evolutionary diversification of fungi.

The 2017 Nobel Prize in Chemistry: cryo-EM comes of age.

PubMed

Shen, Peter S

2018-03-01

The 2017 Nobel Prize in Chemistry was awarded to Jacques Dubochet, Joachim Frank, and Richard Henderson for "developing cryo-electron microscopy (cryo-EM) for the high-resolution structure determination of biomolecules in solution." This feature article summarizes some of the major achievements leading to the development of cryo-EM and recent technological breakthroughs that have transformed the method into a mainstream tool for structure determination.

[Genetic regulation of plant shoot stem cells].

PubMed

Al'bert, E V; Ezhova, T A

2013-02-01

This article describes the main features of plant stem cells and summarizes the results of studies of the genetic control of stem cell maintenance in the apical meristem of the shoot. It is demonstrated that the WUS-CLV gene system plays a key role in the maintenance of shoot apical stem cells and the formation of adventitious buds and somatic embryos. Unconventional concepts of plant stem cells are considered.

The right wing of the LEFT airplane

NASA Technical Reports Server (NTRS)

Powell, Arthur G.

1987-01-01

The NASA Leading-Edge Flight Test (LEFT) program addressed the environmental issues which were potential problems in the application of Laminar Flow Control (LFC) to transport aircraft. These included contamination of the LFC surface due to dirt, rain, insect remains, snow, and ice, in the critical leading-edge region. Douglas Aircraft Company designed and built a test article which was mounted on the right wing of the C-140 JetStar aircraft. The test article featured a retractable leading-edge high-lift shield for contamination protection and suction through perforations on the upper surface for LFC. Following a period of developmental flight testing, the aircraft entered simulated airline service, which included exposure to airborne insects, heavy rain, snow, and icing conditions both in the air and on the ground. During the roughly 3 years of flight testing, the test article has consistently demonstrated laminar flow in cruising flight. The experience with the LEFT experiment was summarized with emphasis on significant test findings. The following items were discussed: test article design and features; suction distribution; instrumentation and transition point reckoning; problems and fixes; system performance and maintenance requirements.

The effect of patient portals on quality outcomes and its implications to meaningful use: a systematic review.

PubMed

Kruse, Clemens Scott; Bolton, Katy; Freriks, Greg

2015-02-10

The Health Information Technology for Economic and Clinical Health (HITECH) Act imposes pressure on health care organizations to qualify for "Meaningful Use". It is assumed that portals should increase patient participation in medical decisions, but whether or not the use of portals improves outcomes remains to be seen. The purpose of this systemic review is to outline and summarize study results on the effect of patient portals on quality, or chronic-condition outcomes as defined by the Agency for Healthcare Research and Quality, and its implications to Meaningful Use since the beginning of 2011. This review updates and builds on the work by Ammenwerth, Schnell-Inderst, and Hoerbst. We performed a systematic literature search in PubMed, CINAHL, and Google Scholar. We identified any data-driven study, quantitative or qualitative, that examined a relationship between patient portals, or patient portal features, and outcomes. We also wanted to relate the findings back to Meaningful Use criteria. Over 4000 articles were screened, and 27 were analyzed and summarized for this systematic review. We identified 26 studies and 1 review, and we summarized their findings and applicability to our research question. Very few studies associated use of the patient portal, or its features, to improved outcomes; 37% (10/27) of papers reported improvements in medication adherence, disease awareness, self-management of disease, a decrease of office visits, an increase in preventative medicine, and an increase in extended office visits, at the patient's request for additional information. The results also show an increase in quality in terms of patient satisfaction and customer retention, but there are weak results on medical outcomes. The results of this review demonstrate that more health care organizations today offer features of a patient portal than in the review published in 2011. Articles reviewed rarely analyzed a full patient portal but instead analyzed features of a portal such as secure messaging, as well as disease management and monitoring. The ability of patients to be able to view their health information electronically meets the intent of Meaningful Use, Stage 2 requirements, but the ability to transmit to a third party was not found in the review.

Usability evaluation of an experimental text summarization system and three search engines: implications for the reengineering of health care interfaces.

PubMed

Kushniruk, Andre W; Kan, Min-Yem; McKeown, Kathleen; Klavans, Judith; Jordan, Desmond; LaFlamme, Mark; Patel, Vimia L

2002-01-01

This paper describes the comparative evaluation of an experimental automated text summarization system, Centrifuser and three conventional search engines - Google, Yahoo and About.com. Centrifuser provides information to patients and families relevant to their questions about specific health conditions. It then produces a multidocument summary of articles retrieved by a standard search engine, tailored to the user's question. Subjects, consisting of friends or family of hospitalized patients, were asked to "think aloud" as they interacted with the four systems. The evaluation involved audio- and video recording of subject interactions with the interfaces in situ at a hospital. Results of the evaluation show that subjects found Centrifuser's summarization capability useful and easy to understand. In comparing Centrifuser to the three search engines, subjects' ratings varied; however, specific interface features were deemed useful across interfaces. We conclude with a discussion of the implications for engineering Web-based retrieval systems.

Genetic data simulators and their applications: an overview

PubMed Central

Peng, Bo; Chen, Huann-Sheng; Mechanic, Leah E.; Racine, Ben; Clarke, John; Gillanders, Elizabeth; Feuer, Eric J.

2016-01-01

Computer simulations have played an indispensable role in the development and application of statistical models and methods for genetic studies across multiple disciplines. The need to simulate complex evolutionary scenarios and pseudo-datasets for various studies has fueled the development of dozens of computer programs with varying reliability, performance, and application areas. To help researchers compare and choose the most appropriate simulators for their studies, we have created the Genetic Simulation Resources (GSR) website, which allows authors of simulation software to register their applications and describe them with more than 160 defined attributes. This article summarizes the properties of 93 simulators currently registered at GSR and provides an overview of the development and applications of genetic simulators. Unlike other review articles that address technical issues or compare simulators for particular application areas, we focus on software development, maintenance, and features of simulators, often from a historical perspective. Publications that cite these simulators are used to summarize both the applications of genetic simulations and the utilization of simulators. PMID:25504286

Fibromyalgia Pathogenesis and Treatment Options Update.

PubMed

Chinn, Steven; Caldwell, William; Gritsenko, Karina

2016-04-01

This review article presents and summarizes up-to-date literature on the clinical manifestations, diagnosis, pathophysiological mechanisms, and treatment options for fibromyalgia patients. First, the most recent diagnostic criteria for fibromyalgia, as put forth by the American College of Rheumatology will be summarized. Clinical features, including chronic widespread pain, hyperalgesia, mood disorders, anxiety, and disturbed sleep patterns will be explored in-depth. The pathogenesis and pathophysiology of fibromyalgia involves alterations in multiple ascending and descending central nervous system pathways, as well as peripheral pathways, leading to heightened pain sensitivity. Risk factors have been studied extensively, and the most recent research focuses on various genetic influences and the contributions of stress and poor sleep. Lastly, the discussion in this article focuses on treatment options for fibromyalgia; some have been mainstay options for many years. Pharmacological agents include tricyclic antidepressants, anti-epileptic drugs, selective serotonin reuptake inhibitors, norepinephrine/serotonin reuptake inhibitors, as well as some investigational agents. The evidence behind non-pharmacologic treatments, including massage therapy, exercise, and acupuncture, are discussed.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chevallier, J.; Turner, L.

This article describes the design and operation of Trident IX a successfully applied jack up system. A summary of Trident IX's two years of operation in the Arabian Gulf and offshore West Africa is presented. The system is compared to conventional jacking systems in terms of design, operation, costs and safety. Dynamic forces at 400 ft. water depths are summarized, and design of the legs to withstand these dynamic forces and accomodate the new system are explained. Features are listed.

Recurrent Corneal Erosions in Corneal Dystrophies: a Review of the Pathogenesis, Differential Diagnosis, and Therapy.

PubMed

Omari, Amro A; Mian, Shahzad I

2018-06-01

Recurrent corneal erosions in corneal dystrophies are visually significant and bothersome to patients. The goal of this article is to review the pathogenesis, differential diagnosis, and management of recurrent corneal erosions in corneal dystrophies. Forty-eight articles and 1 textbook recently published on corneal erosions in corneal dystrophies were reviewed. The findings on the pathogenesis and clinical characteristics of erosions in each dystrophy were summarized. Any contradicting opinions for which the literature was unclear were either omitted or recorded as lacking strong evidence. The epithelial-stromal complex plays an important role in the pathogenesis of erosions in corneal dystrophies. The clinical features of each corneal dystrophy guide their diagnosis and management. A better understanding of the pathogenesis and clinical features of erosions in corneal dystrophies can lead to better clinical outcomes. Georg Thieme Verlag KG Stuttgart · New York.

Low Energy Accelerators for Cargo Inspection

NASA Astrophysics Data System (ADS)

Tang, Chuanxiang

Cargo inspection by X-rays has become essential for seaports and airports. With the emphasis on homeland security issues, the identification of dangerous things, such as explosive items and nuclear materials, is the key feature of a cargo inspection system. And new technologies based on dual energy X-rays, neutrons and monoenergetic X-rays have been studied to achieve sufficiently good material identification. An interpretation of the principle of X-ray cargo inspection technology and the features of X-ray sources are presented in this article. As most of the X-ray sources are based on RF electron linear accelerators (linacs), we give a relatively detailed description of the principle and characteristics of linacs. Cargo inspection technologies based on neutron imaging, neutron analysis, nuclear resonance fluorescence and computer tomography are also mentioned here. The main vendors and their products are summarized at the end of the article.

[The essence of Professor Wu Lian-Zhong's acupuncture manipulation].

PubMed

Liu, Jing; Guo, Yi; Wu, Lian-Zhong

2014-05-01

The painless needle insertion technique, summarized by Professor WU Lian-zhong during his decades of acupuncture clinical practice is introduced in this article, which is characterized as soft, flexible, fast, plucking and activating antipathogenic qi. The Sancai (three layers) lifting and thrusting manipulation technique is adopted by Professor WU for getting the qi sensation. And features of 10 kinds of needling sensation such as soreness, numbness, heaviness, distension, pain, cold, hot, radiation, jumping and contracture are summarized. Finger force, amplitude, speed and time length are also taken as the basis of reinforcing and reducing manipulations. Moreover, examples are also given to explain the needling technique on some specific points which further embodies Professor WU's unique experiences and understandings on acupuncture.

[X-ray diagnostic of partial intestinal obstruction in small intestine diseases: a glance on the problem of radiologist-gastroenterologist].

PubMed

Levchenko, S V; Kotovshchikova, A A; Orlova, N V

2013-01-01

The article is devoted to special features of X-ray examining of patients suffering from acute abdomen pain and X-ray paradigma of some intestine diseases as a cause of partial bowel obstruction. Own clinical data are presented. Long-term experience of our X-ray department is summarized. The possibilities of X-ray examining of abdomen with and without contrast in patients with partial bowel obstruction are described.

Management of resectable gastrointestinal stromal tumor.

PubMed

Chaudhry, Umer I; DeMatteo, Ronald P

2009-02-01

Gastrointestinal stromal tumor (GIST) is a rare neoplasm that recently has become an intense focus of scientific investigation, as it serves as a model for the molecular therapy for cancer. Although surgery remains the principle treatment of primary localized GIST, imatinib mesylate, a selective inhibitor of KIT protein, achieves dramatic responses in metastatic GIST. Multimodality therapy integrating surgery and molecular therapy has shown promise. This article summarizes the epidemiology, clinicopathologic features, natural history, and clinical management of GIST.

Dynamic binding of visual features by neuronal/stimulus synchrony.

PubMed

Iwabuchi, A

1998-05-01

When people see a visual scene, certain parts of the visual scene are treated as belonging together and we regard them as a perceptual unit, which is called a "figure". People focus on figures, and the remaining parts of the scene are disregarded as "ground". In Gestalt psychology this process is called "figure-ground segregation". According to current perceptual psychology, a figure is formed by binding various visual features in a scene, and developments in neuroscience have revealed that there are many feature-encoding neurons, which respond to such features specifically. It is not known, however, how the brain binds different features of an object into a coherent visual object representation. Recently, the theory of binding by neuronal synchrony, which argues that feature binding is dynamically mediated by neuronal synchrony of feature-encoding neurons, has been proposed. This review article portrays the problem of figure-ground segregation and features binding, summarizes neurophysiological and psychophysical experiments and theory relevant to feature binding by neuronal/stimulus synchrony, and suggests possible directions for future research on this topic.

An Overview of Head and Neck Malignancy with Perineural Spread

PubMed Central

Panizza, Benedict J.

2016-01-01

This article provides an overview of perineural spread of head and neck malignancy. It defines the problem and explores some of the unique features, which occur with this pathology. The expectation is for a better understanding of this extraordinary disease, hopefully leading to earlier diagnosis and for a more consistent reporting of results. It summarizes the topics to be covered in this special edition, which should leave the reader with a fairly complete understanding of the contemporary issues of perineural spread. PMID:27123383

An Overview of Head and Neck Malignancy with Perineural Spread.

PubMed

Panizza, Benedict J

2016-04-01

This article provides an overview of perineural spread of head and neck malignancy. It defines the problem and explores some of the unique features, which occur with this pathology. The expectation is for a better understanding of this extraordinary disease, hopefully leading to earlier diagnosis and for a more consistent reporting of results. It summarizes the topics to be covered in this special edition, which should leave the reader with a fairly complete understanding of the contemporary issues of perineural spread.

Minds That Matter: 2007 Gairdner International Awards Lectures

PubMed Central

Krasnoshtein, F.; Nikolov, N.

2007-01-01

On October 25 and 26, 2007, at the University of Toronto, the Gairdner Foundation in partnership with Canadian Institutes of Health Research presented a two-day international symposium titled Minds That Matter. The symposium featured academic lectures by Gairdner Award winners past and present and by other leading biomedical scientists. These distinguished researchers share many characteristics in common: creativity, vision, tenacity, and driving curiosity to illuminate discovery with high degree of relevance. The present article summarizes the 2007 Gairdner Award lectures.

Oral health considerations in anorexia and bulimia nervosa. 1. Symptomatology and diagnosis.

PubMed

Bassiouny, Mohamed A

2017-01-01

Eating disorders have captured the attention of medical and dental professionals as well as the public for decades and continue to raise concern today. The literature devoted to anorexia and bulimia highlights myriad psychological, systemic, and dental health complications. Dental practitioners are in a unique position to discover early manifestations of these disorders. The present article reviews anorexia and bulimia, summarizing telltale behavioral traits, systemic manifestations, and dental features to facilitate recognition and enable accurate diagnosis.

Using cell structures to develop functional nanomaterials and nanostructures--case studies of actin filaments and microtubules.

PubMed

Wu, Kevin Chia-Wen; Yang, Chung-Yao; Cheng, Chao-Min

2014-04-25

This article is based on the continued development of biologically relevant elements (i.e., actin filaments and microtubules in living cells) as building blocks to create functional nanomaterials and nanostructures that can then be used to manufacture nature-inspired small-scale devices or systems. Here, we summarize current progress in the field and focus specifically on processes characterized by (1) robustness and ease of use, (2) inexpensiveness, and (3) potential expandability to mass production. This article, we believe, will provide scientists and engineers with a more comprehensive understanding of how to mine biological materials and natural design features to construct functional materials and devices.

The Effect of Patient Portals on Quality Outcomes and Its Implications to Meaningful Use: A Systematic Review

PubMed Central

2015-01-01

Background The Health Information Technology for Economic and Clinical Health (HITECH) Act imposes pressure on health care organizations to qualify for “Meaningful Use”. It is assumed that portals should increase patient participation in medical decisions, but whether or not the use of portals improves outcomes remains to be seen. Objective The purpose of this systemic review is to outline and summarize study results on the effect of patient portals on quality, or chronic-condition outcomes as defined by the Agency for Healthcare Research and Quality, and its implications to Meaningful Use since the beginning of 2011. This review updates and builds on the work by Ammenwerth, Schnell-Inderst, and Hoerbst. Methods We performed a systematic literature search in PubMed, CINAHL, and Google Scholar. We identified any data-driven study, quantitative or qualitative, that examined a relationship between patient portals, or patient portal features, and outcomes. We also wanted to relate the findings back to Meaningful Use criteria. Over 4000 articles were screened, and 27 were analyzed and summarized for this systematic review. Results We identified 26 studies and 1 review, and we summarized their findings and applicability to our research question. Very few studies associated use of the patient portal, or its features, to improved outcomes; 37% (10/27) of papers reported improvements in medication adherence, disease awareness, self-management of disease, a decrease of office visits, an increase in preventative medicine, and an increase in extended office visits, at the patient’s request for additional information. The results also show an increase in quality in terms of patient satisfaction and customer retention, but there are weak results on medical outcomes. Conclusions The results of this review demonstrate that more health care organizations today offer features of a patient portal than in the review published in 2011. Articles reviewed rarely analyzed a full patient portal but instead analyzed features of a portal such as secure messaging, as well as disease management and monitoring. The ability of patients to be able to view their health information electronically meets the intent of Meaningful Use, Stage 2 requirements, but the ability to transmit to a third party was not found in the review. PMID:25669240

Different approaches for identifying important concepts in probabilistic biomedical text summarization.

PubMed

Moradi, Milad; Ghadiri, Nasser

2018-01-01

Automatic text summarization tools help users in the biomedical domain to acquire their intended information from various textual resources more efficiently. Some of biomedical text summarization systems put the basis of their sentence selection approach on the frequency of concepts extracted from the input text. However, it seems that exploring other measures rather than the raw frequency for identifying valuable contents within an input document, or considering correlations existing between concepts, may be more useful for this type of summarization. In this paper, we describe a Bayesian summarization method for biomedical text documents. The Bayesian summarizer initially maps the input text to the Unified Medical Language System (UMLS) concepts; then it selects the important ones to be used as classification features. We introduce six different feature selection approaches to identify the most important concepts of the text and select the most informative contents according to the distribution of these concepts. We show that with the use of an appropriate feature selection approach, the Bayesian summarizer can improve the performance of biomedical summarization. Using the Recall-Oriented Understudy for Gisting Evaluation (ROUGE) toolkit, we perform extensive evaluations on a corpus of scientific papers in the biomedical domain. The results show that when the Bayesian summarizer utilizes the feature selection methods that do not use the raw frequency, it can outperform the biomedical summarizers that rely on the frequency of concepts, domain-independent and baseline methods. Copyright © 2017 Elsevier B.V. All rights reserved.

Mall Walking Program Environments, Features, and Participants: A Scoping Review.

PubMed

Farren, Laura; Belza, Basia; Allen, Peg; Brolliar, Sarah; Brown, David R; Cormier, Marc L; Janicek, Sarah; Jones, Dina L; King, Diane K; Marquez, David X; Rosenberg, Dori E

2015-08-13

Walking is a preferred and recommended physical activity for middle-aged and older adults, but many barriers exist, including concerns about safety (ie, personal security), falling, and inclement weather. Mall walking programs may overcome these barriers. The purpose of this study was to summarize the evidence on the health-related value of mall walking and mall walking programs. We conducted a scoping review of the literature to determine the features, environments, and benefits of mall walking programs using the RE-AIM framework (reach, effectiveness, adoption, implementation, and maintenance). The inclusion criteria were articles that involved adults aged 45 years or older who walked in indoor or outdoor shopping malls. Exclusion criteria were articles that used malls as laboratory settings or focused on the mechanics of walking. We included published research studies, dissertations, theses, conference abstracts, syntheses, nonresearch articles, theoretical papers, editorials, reports, policy briefs, standards and guidelines, and nonresearch conference abstracts and proposals. Websites and articles written in a language other than English were excluded. We located 254 articles on mall walking; 32 articles met our inclusion criteria. We found that malls provided safe, accessible, and affordable exercise environments for middle-aged and older adults. Programmatic features such as program leaders, blood pressure checks, and warm-up exercises facilitated participation. Individual benefits of mall walking programs included improvements in physical, social, and emotional well-being. Limited transportation to the mall was a barrier to participation. We found the potential for mall walking programs to be implemented in various communities as a health promotion measure. However, the research on mall walking programs is limited and has weak study designs. More rigorous research is needed to define best practices for mall walking programs' reach, effectiveness, adoption, implementation, and maintenance.

Mall Walking Program Environments, Features, and Participants: A Scoping Review

PubMed Central

Belza, Basia; Allen, Peg; Brolliar, Sarah; Brown, David R.; Cormier, Marc L.; Janicek, Sarah; Jones, Dina L.; King, Diane K.; Marquez, David X.; Rosenberg, Dori E.

2015-01-01

Introduction Walking is a preferred and recommended physical activity for middle-aged and older adults, but many barriers exist, including concerns about safety (ie, personal security), falling, and inclement weather. Mall walking programs may overcome these barriers. The purpose of this study was to summarize the evidence on the health-related value of mall walking and mall walking programs. Methods We conducted a scoping review of the literature to determine the features, environments, and benefits of mall walking programs using the RE-AIM framework (reach, effectiveness, adoption, implementation, and maintenance). The inclusion criteria were articles that involved adults aged 45 years or older who walked in indoor or outdoor shopping malls. Exclusion criteria were articles that used malls as laboratory settings or focused on the mechanics of walking. We included published research studies, dissertations, theses, conference abstracts, syntheses, nonresearch articles, theoretical papers, editorials, reports, policy briefs, standards and guidelines, and nonresearch conference abstracts and proposals. Websites and articles written in a language other than English were excluded. Results We located 254 articles on mall walking; 32 articles met our inclusion criteria. We found that malls provided safe, accessible, and affordable exercise environments for middle-aged and older adults. Programmatic features such as program leaders, blood pressure checks, and warm-up exercises facilitated participation. Individual benefits of mall walking programs included improvements in physical, social, and emotional well-being. Limited transportation to the mall was a barrier to participation. Conclusion We found the potential for mall walking programs to be implemented in various communities as a health promotion measure. However, the research on mall walking programs is limited and has weak study designs. More rigorous research is needed to define best practices for mall walking programs’ reach, effectiveness, adoption, implementation, and maintenance. PMID:26270743

Analyzing Neutrophil Morphology, Mechanics, and Motility in Sepsis: Options and Challenges for Novel Bedside Technologies.

PubMed

Zonneveld, Rens; Molema, Grietje; Plötz, Frans B

2016-01-01

Alterations in neutrophil morphology (size, shape, and composition), mechanics (deformability), and motility (chemotaxis and migration) have been observed during sepsis. We combine summarizing features of neutrophil morphology, mechanics, and motility that change during sepsis with an investigation into their clinical utility as markers for sepsis through measurement with novel technologies. We performed an initial literature search in MEDLINE using search terms "neutrophil," "morphology," "mechanics," "dynamics," "motility," "mobility," "spreading," "polarization," "migration," and "chemotaxis." We then combined the results with "sepsis" and "septic shock." We scanned bibliographies of included articles to identify additional articles. Final selection was done after the authors reviewed recovered articles. We included articles based on their relevance for our review topic. When compared with resting conditions, sepsis causes an increase in circulating numbers of larger, more rigid neutrophils that show diminished granularity, migration, and chemotaxis. Combined measurement of these variables could provide a more complete view on neutrophil phenotype manifestation. For that purpose, sophisticated automated hematology analyzers, microscopy, and bedside microfluidic devices provide clinically feasible, high-throughput, and cost-limiting means. We propose that integration of features of neutrophil morphology, mechanics, and motility with these new analytical methods can be useful as markers for diagnosis, prognosis, and monitoring of sepsis and may even contribute to basic understanding of its pathophysiology.

Psychology of male and female communicative activity.

PubMed

Vasyura, Svetlana A

2008-05-01

The article features a brief overview of theoretical and empirical studies in communication psychology and sociability of men and women, boys and girls. Russian and foreign studies are summarized to point out that girls and women place greater emphasis on communication and interpersonal relations than do boys and men. Moreover, female communication is more emotional. The article presents the results of the author's own empirical study of male and female communicative activity. Communicative activity is viewed as a complex psychological phenomenon, a degree of the subject's willingness to interact. Communicative activity was studied with the test proposed by the Russian psychologist, Krupnov, and designed to detect the following components of communicative activity: dynamic (natural), emotional, motivational, cognitive, regulatory, productive, and two sorts of communication difficulties (operational and personal). Gender differences in communicative activity are shown on a sample of 480 participants aged 18-40 (240 men and 240 women). The article then describes communicative styles of adolescents (130 boys and 130 girls, aged 19-24). Various communicative styles are featured, including "energetic, businesslike," "conformal, emotional," "diplomatic, externally oriented" for boys and "energetic, sociable," "emotional, difficult," and "complaisant, expressive" for girls. Every person's individuality and gender identity are shown to impact their communicative style.

Research Summaries

ERIC Educational Resources Information Center

Brock, Stephen E., Ed.; Bratica, Robyn; Dempsey, Jack R.; Karle, Jessica

2009-01-01

This article presents summaries of recent crisis management publications. The first article summarized provides a review of research documenting that even when children are not physically proximal to a national disaster (9/11), they may still have negative reactions. The second article summarized is an examination of the PTSD diagnostic criterion…

[Advances in metabolic engineering of Escherichia coli for isoprene biosynthesis].

PubMed

Guo, Jing; Cao, Yujin; Xian, Mo; Liu, Huizhou

2016-08-25

As an important industrial chemical, isoprene is mainly used as a precursor for synthetic rubbers. In addition, it also has wide applications in the field of pharmaceutical and chemical intermediates, food, adhesives and aviation fuel. Compared with conventional petrochemical routes, production of isoprene in microbial systems has been the research focus considering environment friendly and sustainable development features. This article summarizes the metabolic pathways and key enzymes of isoprene biosynthesis, reviews current methods and strategies in improving isoprene production of Escherichia coli, and also gives some basic ideas and expectation.

[Research progress of bonding strength between porcelain veneer and enamel].

PubMed

Cheng, Hong; Zhang, Fu-qiang

2014-02-01

Porcelain veneer had gained more and more attention in dental clinical applications due to its advantages such as good esthetic effects and minor invasiveness. The reliable and consistent adhesive bonding were the key to success. The enamel which featured high mineralization and low moisture would be the ideal bonding part for porcelain veneer. This article was aimed to summarize the research progress regarding to those factors that might had effect on the bonding strength between the porcelain veneer and the enamel including the restoration types of resin adhesives and bonding surface preparations.

14th International Congress on Antiphospholipid Antibodies Task Force Report on Catastrophic Antiphospholipid Syndrome.

PubMed

Cervera, Ricard; Rodríguez-Pintó, Ignasi; Colafrancesco, Serena; Conti, Fabrizio; Valesini, Guido; Rosário, Cristina; Agmon-Levin, Nancy; Shoenfeld, Yehuda; Ferrão, Claudia; Faria, Raquel; Vasconcelos, Carlos; Signorelli, Flavio; Espinosa, Gerard

2014-07-01

The 'Task Force on Catastrophic Antiphospholipid Syndrome (CAPS)' was developed on the occasion of the 14th International Congress on Antiphospholipid Antibodies. The objectives of this Task Force were to assess the current knowledge on pathogenesis, clinical and laboratory features, diagnosis and classification, precipitating factors and treatment of this condition in order to address recommendations for future research. This article summarizes the studies analyzed by the Task Force, its recommendations and the future research agenda. Copyright © 2014 Elsevier B.V. All rights reserved.

Creative partnerships for funding nursing research.

PubMed

McCann, Judith J; Hills, Elizabeth Blanchard; Zauszniewski, Jaclene A; Smith, Carol E; Farran, Carol J; Wilkie, Diana J

2011-02-01

The Small Business Innovation Research (SBIR) program and the Small Business Technology Transfer Research (STTR) program are two federal funding mechanisms that some nurses in academic positions have used to support research and development of innovative nursing products or services. Both the SBIR and STTR mechanisms are excellent sources of funding for nurse researchers who want to capitalize on relationships with small businesses or obtain seed money to fund high-risk projects with potential to attract new venture capital. This article provides an overview of National Institutes of Health (NIH)-funded SBIR and STTR programs and summarizes similarities and differences between the programs. The article also describes unique features of NIH SBIR and STTR funding mechanisms that differentiate them from other R-series funding mechanisms, reviews evaluation criteria for SBIR and STTR projects, and discusses critical partners and resources for proposal development. Finally, the article describes characteristics of successful partnerships and provides examples of SBIR/STTR-funded projects.

Posterior Rigid Instrumentation of C7: Surgical Considerations and Biomechanics at the Cervicothoracic Junction. A Review of the Literature.

PubMed

Bayoumi, Ahmed B; Efe, Ibrahim E; Berk, Selim; Kasper, Ekkehard M; Toktas, Zafer Orkun; Konya, Deniz

2018-03-01

The cervicothoracic junction is a challenging anatomic transition in spine surgery. It is commonly affected by different types of diseases that may significantly impair stability in this region. The seventh cervical vertebra (C7) is an atypical cervical vertebra with unique anatomic features compared to subaxial cervical spine (C3 to C6). C7 has relatively broader laminae, larger pedicles, smaller lateral masses, and a long nonbifid spinous process. These features allow a variety of surgical methods for performing posterior rigid instrumentation in the form of different types of screws, such as lateral mass screws, pedicle screws, transfacet screws, and intralaminar screws. Many biomechanical studies on cadavers have evaluated and compared different types of implants at C7. We reviewed PubMed/Medline by using specific combinations of keywords to summarize previously published articles that examined C7 posterior rigid instrumentation thoroughly in an experimental fashion on patients or cadavers with additional descriptive radiologic parameters for evaluation of the optimum surgical technique for each type. A total of 44 articles were reported, including 22 articles that discussed anatomic considerations (entry points, sagittal and axial trajectories, and features of screws) and another 22 articles that discussed the relevant biomechanical testing at this transitional region if C7 was directly involved in terms of receiving posterior rigid implants. C7 can accommodate different types of screws, which can provide additional benefits and risks based on availability of bony purchase, awareness of surgical technique, biomechanics, and anatomic considerations. Copyright © 2017 Elsevier Inc. All rights reserved.

Clinical and laboratory diagnosis of von Willebrand disease: A synopsis of the 2008 NHLBI/NIH guidelines

PubMed Central

Nichols, William L.; Rick, Margaret E.; Ortel, Thomas L.; Montgomery, Robert R.; Sadler, J. Evan; Yawn, Barbara P.; James, Andra H.; Hultin, Mae B.; Manco-Johnson, Marilyn J.; Weinstein, Mark

2017-01-01

Von Willebrand factor (VWF) mediates blood platelet adhesion and accumulation at sites of blood vessel injury, and also carries coagulation factor VIII (FVIII) that is important for generating procoagulant activity. Von Willebrand disease (VWD), the most common inherited bleeding disorder, affects males and females, and reflects deficiency or defects of VWF that may also cause decreased FVIII. It may also occur less commonly as an acquired disorder (acquired von Willebrand syndrome). This article briefly summarizes selected features of the March 2008 evidence-based clinical and laboratory diagnostic recommendations from the National Heart, Lung, and Blood Institute (NHLBI) Expert Panel for assessment for VWD or other bleeding disorders or risks. Management of VWD is also addressed in the NHLBI guidelines, but is not summarized here. The VWD guidelines are available at the NHLBI Web site (http://www.nhlbi.nih.gov/guidelines/vwd). PMID:19415721

Using ontology-based semantic similarity to facilitate the article screening process for systematic reviews.

PubMed

Ji, Xiaonan; Ritter, Alan; Yen, Po-Yin

2017-05-01

Systematic Reviews (SRs) are utilized to summarize evidence from high quality studies and are considered the preferred source of evidence-based practice (EBP). However, conducting SRs can be time and labor intensive due to the high cost of article screening. In previous studies, we demonstrated utilizing established (lexical) article relationships to facilitate the identification of relevant articles in an efficient and effective manner. Here we propose to enhance article relationships with background semantic knowledge derived from Unified Medical Language System (UMLS) concepts and ontologies. We developed a pipelined semantic concepts representation process to represent articles from an SR into an optimized and enriched semantic space of UMLS concepts. Throughout the process, we leveraged concepts and concept relations encoded in biomedical ontologies (SNOMED-CT and MeSH) within the UMLS framework to prompt concept features of each article. Article relationships (similarities) were established and represented as a semantic article network, which was readily applied to assist with the article screening process. We incorporated the concept of active learning to simulate an interactive article recommendation process, and evaluated the performance on 15 completed SRs. We used work saved over sampling at 95% recall (WSS95) as the performance measure. We compared the WSS95 performance of our ontology-based semantic approach to existing lexical feature approaches and corpus-based semantic approaches, and found that we had better WSS95 in most SRs. We also had the highest average WSS95 of 43.81% and the highest total WSS95 of 657.18%. We demonstrated using ontology-based semantics to facilitate the identification of relevant articles for SRs. Effective concepts and concept relations derived from UMLS ontologies can be utilized to establish article semantic relationships. Our approach provided a promising performance and can easily apply to any SR topics in the biomedical domain with generalizability. Copyright © 2017 Elsevier Inc. All rights reserved.

Breast manifestations of systemic diseases

PubMed Central

Dilaveri, Christina A; Mac Bride, Maire Brid; Sandhu, Nicole P; Neal, Lonzetta; Ghosh, Karthik; Wahner-Roedler, Dietlind L

2012-01-01

Although much emphasis has been placed on the primary presentations of breast cancer, little focus has been placed on how systemic illnesses may affect the breast. In this article, we discuss systemic illnesses that can manifest in the breast. We summarize the clinical features, imaging, histopathology, and treatment recommendations for endocrine, vascular, systemic inflammatory, infectious, and hematologic diseases, as well as for the extramammary malignancies that can present in the breast. Despite the rarity of these manifestations of systemic disease, knowledge of these conditions is critical to the appropriate evaluation and treatment of patients presenting with breast symptoms. PMID:22371658

MPEG content summarization based on compressed domain feature analysis

NASA Astrophysics Data System (ADS)

Sugano, Masaru; Nakajima, Yasuyuki; Yanagihara, Hiromasa

2003-11-01

This paper addresses automatic summarization of MPEG audiovisual content on compressed domain. By analyzing semantically important low-level and mid-level audiovisual features, our method universally summarizes the MPEG-1/-2 contents in the form of digest or highlight. The former is a shortened version of an original, while the latter is an aggregation of important or interesting events. In our proposal, first, the incoming MPEG stream is segmented into shots and the above features are derived from each shot. Then the features are adaptively evaluated in an integrated manner, and finally the qualified shots are aggregated into a summary. Since all the processes are performed completely on compressed domain, summarization is achieved at very low computational cost. The experimental results show that news highlights and sports highlights in TV baseball games can be successfully extracted according to simple shot transition models. As for digest extraction, subjective evaluation proves that meaningful shots are extracted from content without a priori knowledge, even if it contains multiple genres of programs. Our method also has the advantage of generating an MPEG-7 based description such as summary and audiovisual segments in the course of summarization.

Conference report: hot topics in antibody-drug conjugate development.

PubMed

Thudium, Karen; Bilic, Sanela

2013-12-01

American Association of Pharmaceutical Scientists National Biotechnology Conference Sheraton San Diego Hotel and Marina, San Diego, CA, USA, 19-23 May 2013 The National Biotechnology Conference, is a premier meeting for biotechnology professionals covering a broad range of hot topics in the biotechnology industry. Attracting participants from academia, industry and regulatory, this meeting features sessions that aim to address emerging subjects of interest and allows for open exchange between scientists. The 2013 conference featured leading researchers in the fields of antibody-drug conjugates (ADCs) and immunogenicity. Herein, we present a summary of the ADC hot topics, including bioanalytical and PK considerations, quantitative evaluation of the impact of immunogenicity and ADME to understand ADC drug-drug interactions, and clinical considerations for ADC development. This article aims to summarize the recommendations that were made by the speakers during various sessions throughout the conference.

Regime shifts and panarchies in regional scale social ...

EPA Pesticide Factsheets

In this article we summarize histories of nonlinear, complex interactions among societal, legal, and ecosystem dynamics in six North American water basins, as they respond to changing climate. These case studies were chosen to explore the conditions for emergence of adaptive governance in heavily regulated and developed social-ecological systems nested within a hierarchical governmental system. We summarize resilience assessments conducted in each system to provide a synthesis and reference by the other articles in this special feature. We also present a general framework used to evaluate the interactions between society and ecosystem regimes and the governance regimes chosen to mediate those interactions. The case studies show different ways that adaptive governance may be triggered, facilitated, or constrained by ecological and/or legal processes. The resilience assessments indicate that complex interactions among the governance and ecosystem components of these systems can produce different trajectories, which include patterns of (a) development and stabilization, (b) cycles of crisis and recovery, which includes lurches in adaptation and learning, and (3) periods of innovation, novelty, and transformation. Exploration of cross scale (Panarchy) interactions among levels and sectors of government and society illustrate that they may constrain development trajectories, but may also provide stability during crisis or innovation at smaller scales; create crises,

Figure summarizer browser extensions for PubMed Central

PubMed Central

Agarwal, Shashank; Yu, Hong

2011-01-01

Summary: Figures in biomedical articles present visual evidence for research facts and help readers understand the article better. However, when figures are taken out of context, it is difficult to understand their content. We developed a summarization algorithm to summarize the content of figures and used it in our figure search engine (http://figuresearch.askhermes.org/). In this article, we report on the development of web browser extensions for Mozilla Firefox, Google Chrome and Apple Safari to display summaries for figures in PubMed Central and NCBI Images. Availability: The extensions can be downloaded from http://figuresearch.askhermes.org/articlesearch/extensions.php. Contact: agarwal@uwm.edu PMID:21493658

Pulmonary nodule characterization, including computer analysis and quantitative features.

PubMed

Bartholmai, Brian J; Koo, Chi Wan; Johnson, Geoffrey B; White, Darin B; Raghunath, Sushravya M; Rajagopalan, Srinivasan; Moynagh, Michael R; Lindell, Rebecca M; Hartman, Thomas E

2015-03-01

Pulmonary nodules are commonly detected in computed tomography (CT) chest screening of a high-risk population. The specific visual or quantitative features on CT or other modalities can be used to characterize the likelihood that a nodule is benign or malignant. Visual features on CT such as size, attenuation, location, morphology, edge characteristics, and other distinctive "signs" can be highly suggestive of a specific diagnosis and, in general, be used to determine the probability that a specific nodule is benign or malignant. Change in size, attenuation, and morphology on serial follow-up CT, or features on other modalities such as nuclear medicine studies or MRI, can also contribute to the characterization of lung nodules. Imaging analytics can objectively and reproducibly quantify nodule features on CT, nuclear medicine, and magnetic resonance imaging. Some quantitative techniques show great promise in helping to differentiate benign from malignant lesions or to stratify the risk of aggressive versus indolent neoplasm. In this article, we (1) summarize the visual characteristics, descriptors, and signs that may be helpful in management of nodules identified on screening CT, (2) discuss current quantitative and multimodality techniques that aid in the differentiation of nodules, and (3) highlight the power, pitfalls, and limitations of these various techniques.

Estimation and interpretation of genetic effects with epistasis using the NOIA model.

PubMed

Alvarez-Castro, José M; Carlborg, Orjan; Rönnegård, Lars

2012-01-01

We introduce this communication with a brief outline of the historical landmarks in genetic modeling, especially concerning epistasis. Then, we present methods for the use of genetic modeling in QTL analyses. In particular, we summarize the essential expressions of the natural and orthogonal interactions (NOIA) model of genetic effects. Our motivation for reviewing that theory here is twofold. First, this review presents a digest of the expressions for the application of the NOIA model, which are often mixed with intermediate and additional formulae in the original articles. Second, we make the required theory handy for the reader to relate the genetic concepts to the particular mathematical expressions underlying them. We illustrate those relations by providing graphical interpretations and a diagram summarizing the key features for applying genetic modeling with epistasis in comprehensive QTL analyses. Finally, we briefly review some examples of the application of NOIA to real data and the way it improves the interpretability of the results.

[Current situation of clinical research on impacted premolars].

PubMed

Liu, Ran-Ran; Tian, Jun

2018-04-01

Teeth impaction is a common developmental malformation in oral diseases. Impacted teeth are usually the canines, third molar, central incisors, premolars, and second molars. The prevalence of impaction of maxillary canines and mandibular wisdom teeth is higher than that of other teeth. Most recent studies have focused on the canines and third molars, but research on impacted premolars is limited. In clinical practice, the majority of orthodontic patients require premolar extraction. Thus, impacted premolars play important roles in orthodontic design and prognosis. This article provides an overview of recent research on impacted premolars and summarizes epidemiological features, localizations, and treatments, with the aim of guiding practitioners on orthodontic design and therapy.

Unlocking the Sugar ‘Steric Gate’ of DNA Polymerases†

PubMed Central

Brown, Jessica A.; Suo, Zucai

2011-01-01

To maintain genomic stability, ribonucleotide incorporation during DNA synthesis is controlled predominantly at the DNA polymerase level. A steric clash between the 2′-hydroxyl of an incoming ribonucleotide and a bulky active site residue, known as the ‘steric gate’, establishes an effective mechanism for most DNA polymerases to selectively insert deoxyribonucleotides. Recent kinetic, structural, and in vivo studies have illuminated novel features about ribonucleotide exclusion and the mechanistic consequences of ribonucleotide misincorporation on downstream events, such as the bypass of a ribonucleotide in a DNA template and the subsequent extension of the DNA lesion bypass product. These important findings are summarized in this review article. PMID:21226515

Management of the Preterm Infant with Congenital Heart Disease.

PubMed

Axelrod, David M; Chock, Valerie Y; Reddy, V Mohan

2016-03-01

The premature neonate with congenital heart disease (CHD) represents a challenging population for clinicians and researchers. The interaction between prematurity and CHD is poorly understood; epidemiologic study suggests that premature newborns are more likely to have CHD and that fetuses with CHD are more likely to be born premature. Understanding the key physiologic features of this special patient population is paramount. Clinicians have debated optimal timing for referral for cardiac surgery, and management in the postoperative period has rapidly advanced. This article summarizes the key concepts and literature in the care of the premature neonate with CHD. Copyright © 2016 Elsevier Inc. All rights reserved.

Process parameter-growth environment-film property relationships for reactive sputter deposited metal (V, Nb, Zr, Y, Au) oxide, nitride, and oxynitride films. Final report, 1 January 1989-30 June 1993

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aita, C.R.

1993-09-30

The research developed process parameter-growth environment-film property relations (phase maps) for model sputter-deposited transition metal oxides, nitrides, and oxynitrides grown by reactive sputter deposition at low temperature. Optical emission spectrometry was used for plasma diagnostics. The results summarized here include the role of sputtered metal-oxygen molecular flux in oxide film growth; structural differences in highest valence oxides including conditions for amorphous growth; and using fundamental optical absorption edge features to probe short range structural disorder. Eight appendices containing sixteen journal articles are included.

[Long QT syndrome. History, genetics, clinical symptoms, causes and therapy].

PubMed

Krönauer, T; Friederich, P

2015-08-01

The long QT syndrome is caused by a change in cardiac repolarization due to functional ion channel defects. A differentiation is made between a congenital (cLQTS) and an acquired (aLQTS) form of the disease. The disease results in the name-giving prolongation of the QT interval in the electrocardiogram and represents a predisposition for cardiac arrhythmia and sudden cardiac death. This article summarizes the current knowledge on the history, pathophysiology, clinical symptoms and therapy of cLQTS and aLQTS. This knowledge of pathophysiological features of the symptoms allows the underlying anesthesiological approach for individualized perioperative concepts for patients suffering from LQTS to be derived.

Dissecting the Components of Long-Term Potentiation

PubMed Central

Blundon, Jay A.; Zakharenko, Stanislav S.

2009-01-01

The formation of memories relies on plastic changes at synapses between neurons. Although the mechanisms of synaptic plasticity have been studied extensively over several decades, many aspects of this process remain controversial. The cellular locus of expression of long-term potentiation (LTP), a major form of synaptic plasticity, is one of the most important unresolved phenomena. In this article, we summarize some recent advances in this area made possible by the development of new imaging tools. These studies have demonstrated that LTP is compound in nature and consists of both presynaptic and postsynaptic components. We also review some features of presynaptic and postsynaptic changes during compound LTP. PMID:18940785

From chaos to calm: one jail system's struggle with suicide prevention.

PubMed

Hayes, L M

1997-01-01

This article profiles the suicide prevention practices at a large metropolitan jail, a facility that experienced nine inmate suicides in a recent 24-month period. The suicide rate in this facility was found to far exceed the rate for jails of comparable size as well as the national rate of jail suicides. The nine suicides are summarized and common features (including the issue of protective custody) of the deaths and systemic jail deficiencies are discussed. The process by which the jail system developed a suicide prevention program based upon the principles of staff training, identification/screening, communication, levels of supervision, housing, and intervention is offered.

Static design of steel-concrete lining for traffic tunnels

NASA Astrophysics Data System (ADS)

Vojtasik, Karel; Mohyla, Marek; Hrubesova, Eva

2017-09-01

Article summarizes the results of research focused on the structural design of traffic tunnel linings that have been achieved in the framework of a research project TE01020168 that supports The Technology Agency of Czech Republic. This research aim is to find and develop a process for design structure parameters of tunnel linings. These are now mostly build up by a shotcrete technology. The shotcrete is commonly endorsed either with steel girders or steel fibres. Since the installation a lining structure is loaded while strength and deformational parameters of shotcrete start to rise till the setting time elapses. That’s reason why conventional approaches of reinforced concrete are not suitable. As well as there are other circumstances to step in shown in this article. Problem is solved by 3D analysis using numerical model that takes into account all the significant features of a tunnel lining construction process inclusive the interaction between lining structure with rock massive. Analysis output is a view into development of stress-strain state in respective construction parts of tunnel lining the whole structure around, including impact on stability of rock massive. The proposed method comprises all features involved in tunnel fabrication including geotechnics and construction technologies.

T cell lymphomatoid contact dermatitis: a challenging case and review of the literature.

PubMed

Knackstedt, Thomas J; Zug, Kathryn A

2015-02-01

Lymphomatoid contact dermatitis is a pseudolymphoma with clinical and histological features of allergic contact dermatitis and cutaneous T cell lymphoma. Incorrect diagnosis may lead to unnecessary testing, unnecessary treatment, or patient harm. The objective of this study is to present a case to demonstrate the diagnostic challenge and overlap between allergic contact dermatitis and cutaneous T cell lymphoma in a patient with lymphomatoid contact dermatitis caused by methylchoroisothiazolinone/methylisothiazolinone and paraben mix, and to review the existing literature in order to summarize the demographics, clinical features, allergens and treatments reported for lymphomatoid contact dermatitis. A search of major scientific databases was conducted for English-language articles reporting cases of lymphomatoid contact dermatitis or additional synonymous search headings. Nineteen articles with a total of 23 patients were analysed. Lymphomatoid contact dermatitis was more common in men, with an average age of 58.5 years. Fourteen unique allergens were identified and confirmed by patch testing. However, no single test or study was diagnostic of lymphomatoid contact dermatitis. Allergen avoidance was the most useful management tool, but selected patients required topical or systemic immunosuppression. In conclusion, without specific diagnostic features, evaluation for lymphomatoid contact dermatitis should include a thorough history and examination, patch testing, and biopsy with immunohistochemistry and clonality studies. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Human use regulatory affairs advisor (HURAA): learning about research ethics with intelligent learning modules.

PubMed

Hu, Xiangen; Graesser, Arthur C

2004-05-01

The Human Use Regulatory Affairs Advisor (HURAA) is a Web-based facility that provides help and training on the ethical use of human subjects in research, based on documents and regulations in United States federal agencies. HURAA has a number of standard features of conventional Web facilities and computer-based training, such as hypertext, multimedia, help modules, glossaries, archives, links to other sites, and page-turning didactic instruction. HURAA also has these intelligent features: (1) an animated conversational agent that serves as a navigational guide for the Web facility, (2) lessons with case-based and explanation-based reasoning, (3) document retrieval through natural language queries, and (4) a context-sensitive Frequently Asked Questions segment, called Point & Query. This article describes the functional learning components of HURAA, specifies its computational architecture, and summarizes empirical tests of the facility on learners.

Global Emergency Medicine Journal Club: A Social Media Discussion About the Outpatient Management of Patients With Spontaneous Pneumothorax by Using Pigtail Catheters.

PubMed

Trueger, N Seth; Murray, Heather; Kobner, Scott; Lin, Michelle

2015-10-01

Annals of Emergency Medicine collaborated with an educational Web site, Academic Life in Emergency Medicine (ALiEM) to host a public discussion featuring the 2014 Annals article on the outpatient management of patients with a spontaneous pneumothorax by using pigtail catheters. The objective was to curate a 14-day (November 10 to 23, 2014) worldwide academic dialogue among clinicians about the article. Four online facilitators hosted the multimodal discussion on the ALiEM Web site, Twitter, and Google Hangout. Comments across the social media platforms were curated for this report, as framed by 4 preselected questions. Engagement was tracked through Web analytic tools. Blog comments, tweets, and video expert commentary involving the featured article are summarized and reported. The dialogue resulted in 1,023 page views from 347 cities in 49 countries on the ALiEM Web site, 279,027 Twitter impressions, and 88 views of the video interview with experts. This Global Emergency Medicine Journal Club created a virtual community of practice from around the world and identified common themes around the management of spontaneous pneumothorax, which included substantial practice variation in regard to inpatient versus outpatient management, location of chest tube, the use of aspiration, and chest radiography after placement. Copyright © 2015 American College of Emergency Physicians. Published by Elsevier Inc. All rights reserved.

Summarizing Expository Texts

ERIC Educational Resources Information Center

Westby, Carol; Culatta, Barbara; Lawrence, Barbara; Hall-Kenyon, Kendra

2010-01-01

Purpose: This article reviews the literature on students' developing skills in summarizing expository texts and describes strategies for evaluating students' expository summaries. Evaluation outcomes are presented for a professional development project aimed at helping teachers develop new techniques for teaching summarization. Methods: Strategies…

Psychological impact of abortion: methodological and outcomes summary of empirical research between 1966 and 1988.

PubMed

Rogers, J L; Stoms, G B; Phifer, J L

1989-01-01

A systematic "roadmap" through the medical literature that empirically examines the incidence of psychological sequelae of induced abortion is presented. Because outcome incidence rates and methodological profiles vary substantially across studies, selective use of articles from this literature without an accompanying rationale for that selectivity could foster erroneous conclusions. Information compiled here can facilitate a rapid methodological critique of citations in abortion-related materials. Investigations published in English between January 1966 and April 1988 that quantitatively examined psychological sequelae using prospective, retrospective, or comparative methodologies are summarized in tables to produce a synopsis of the demographics, methodological limitations, and gross statistical features of each article. This quantitative guide is designed to facilitate appropriate use of the current literature, provide needed background to assess positions arising from the currently available data, and provide methodological focus for planning better studies in the future.

Systems for deep brain stimulation: review of technical features.

PubMed

Amon, A; Alesch, F

2017-09-01

The use of deep brain stimulation (DBS) is an important treatment option for movement disorders and other medical conditions. Today, three major manufacturers provide implantable systems for DBS. Although the underlying principle is basically the same for all available systems, the differences in the technical features vary considerably. This article outlines aspects regarding the technical features of DBS systems. The differences between voltage and current sources are addressed and their effect on stimulation is shown. To maintain clinical benefit and minimize side effects the stimulation field has to be adapted to the requirements of the patient. Shaping of the stimulation field can be achieved by the electrode design and polarity configuration. Furthermore, the electric signal consisting of stimulation rate, stimulation amplitude and pulse width affect the stimulation field. Interleaving stimulation is an additional concept, which permits improved treatment outcomes. Therefore, the electrode design, the polarity, the electric signal, and the concept of interleaving stimulation are presented. The investigated systems can be also categorized as rechargeable and non-rechargeable, which is briefly discussed. Options for interconnecting different system components from various manufacturers are presented. The present paper summarizes the technical features and their combination possibilities, which can have a major impact on the therapeutic effect.

Research Summaries

ERIC Educational Resources Information Center

Brock, Stephen E., Ed.

2009-01-01

This article presents summaries of three recent crisis management publications: (1) "The Impact of School Violence on School Personnel," summarized by Kimberly de Deaux; (2) "Children Exposed to War/Terrorism," summarized by Jennifer DeFago; and (3) "Suicide Survivors Seeking Mental Health Services," summarized by Kimberly de Deaux. The first…

Modeling Autistic Features in Animals

PubMed Central

Patterson, Paul H.

2011-01-01

A variety of features of autism can be simulated in rodents, including the core behavioral hallmarks of stereotyped and repetitive behaviors, and deficits in social interaction and communication. Other behaviors frequently found in autism spectrum disorders (ASD) such as neophobia, enhanced anxiety, abnormal pain sensitivity and eye blink conditioning, disturbed sleep patterns, seizures, and deficits in sensorimotor gating are also present in some of the animal models. Neuropathology and some characteristic neurochemical changes that are frequently seen in autism, as well as alterations in the immune status in the brain and periphery are also found in some of the models. Several known environmental risk factors for autism have been successfully established in rodents, including maternal infection and maternal valproate administration. Also under investigation are a number of mouse models based on genetic variants associated with autism or on syndromic disorders with autistic features. This review briefly summarizes recent developments in this field, highlighting models with face and/or construct validity, and noting the potential for investigation of pathogenesis and early progress towards clinical testing of potential therapeutics. Wherever possible, reference is made to reviews rather than primary articles. PMID:21289542

Aerothermodynamic Insight From The HIFIRE Program

NASA Astrophysics Data System (ADS)

Kimmel, Roger L.; Adamczak, David; Dolvin, Douglas; Borg, Matthew; Stanfield, Scott

2011-05-01

The HIFiRE (Hypersonic International Flight Research and Experimentation) program is a joint venture of the United States Air Force Research Laboratory and Australian Defence Science and Technology Organisation to utilize economical flight research opportunities in the exploration of flight science issues for space access systems. Flights 1 and 5 focus on collecting high-resolution experimental data on critical aerothermodynamic phenomena, including laminar-turbulent transition and shock/boundary layer interactions. Flight 1, successfully flown in March 2010, employed a test article composed of a 7-deg right angle cone, followed by a cylinder and flare. The test article remained attached to the second-stage booster throughout the ballistic trajectory. Flight 5, to be launched in a similar fashion, will feature a 2:1 elliptic cross-section cone as the test article. For both flights significant resources have been invested in pre-flight aerothermodynamic analysis and testing. This manuscript will summarize the overall strategy of the HIFiRE program, review the pre-flight aerothermodynamic analysis for Flights 1 and 5, and present a brief look at preliminary results from the post-flight analysis of Flight 1.

Intramuscular Lipoma: A Review of the Literature

PubMed Central

McTighe, Shane; Chernev, Ivan

2014-01-01

Lipomas are the most common type of soft tissue mesenchymal tumors. They are typically located subcutaneously and consist of mature fatty tissue. When they occur under the enclosing fascia, they are called deep-seated lipomas. Infrequently, lipomas can arise inside the muscle and are called intramuscular lipomas. Intramuscular lipomas have been commonly investigated and categorized in the same group as other deep-seated and superficial lipomatous lesions. Their clinical, histological and imaging characteristics may resemble well-differentiated liposarcomas, further adding to the difficulties in the differential diagnosis. This article summarizes the available literature and describes the typical epidemiological, pathological and clinical features of intramuscular lipomas, as well as delineating their treatment and prognosis. PMID:25568733

Clinical practice guideline: allergic rhinitis executive summary.

PubMed

Seidman, Michael D; Gurgel, Richard K; Lin, Sandra Y; Schwartz, Seth R; Baroody, Fuad M; Bonner, James R; Dawson, Douglas E; Dykewicz, Mark S; Hackell, Jesse M; Han, Joseph K; Ishman, Stacey L; Krouse, Helene J; Malekzadeh, Sonya; Mims, James Whit W; Omole, Folashade S; Reddy, William D; Wallace, Dana V; Walsh, Sandra A; Warren, Barbara E; Wilson, Meghan N; Nnacheta, Lorraine C

2015-02-01

The American Academy of Otolaryngology-Head and Neck Surgery Foundation (AAO-HNSF) has published a supplement to this issue featuring the new Clinical Practice Guideline: Allergic Rhinitis. To assist in implementing the guideline recommendations, this article summarizes the rationale, purpose, and key action statements. The 14 recommendations developed address the evaluation of patients with allergic rhinitis, including performing and interpretation of diagnostic testing and assessment and documentation of chronic conditions and comorbidities. It will then focus on the recommendations to guide the evaluation and treatment of patients with allergic rhinitis, to determine the most appropriate interventions to improve symptoms and quality of life for patients with allergic rhinitis. © American Academy of Otolaryngology—Head and Neck Surgery Foundation 2014.

[Update on chronic pancreatitis: review article].

PubMed

Czul, Frank; Coronel, Emmanuel; Donet, Jean A

2017-01-01

Chronic pancreatitis is a progressive fibro-inflammatory disease of the pancreas characterized by irreversible fibrosis of the gland with eventual failure of exocrine and endocrine functions and hallmark features of abdominal pain, malabsorption, malnutrition, diabetes mellitus and pancreatic calcifications. In many patients this disease results from a complex mix of environmental (eg, alcohol, cigarettes, and occupational chemicals), genetic factors and a few patients with hereditary or autoimmune disease. The management includes medical, endoscopic and surgical approaches with the need for interaction between various specialties, calling for a concerted multidisciplinary approach. This review provides the reader with a comprehensive overview of the studies summarizing the epidemiology, etiology, physiopatology, clinical manifestation, diagnosis and treatments of the disease.

Best of the Radiosurgery Society® Scientific Meeting 2014: stereotactic radiosurgery/stereotactic body radiotherapy treatment of extracranial and intracranial lesions.

PubMed

Mahadevan, Anand; Bucholz, Richard; Gaya, Andrew M; Kresl, John J; Mantz, Constantine; Minnich, Douglas J; Muacevic, Alexander; Medbery, Clinton; Yang, Jun; Caglar, Hale Basak; Davis, Joanne N

2014-12-01

The SRS/SBRT Scientific Meeting 2014, Minneapolis, MN, USA, 7-10 May 2014. The Radiosurgery Society(®), a professional medical society dedicated to advancing the field of stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT), held the international Radiosurgery Society Scientific Meeting, from 7-10 May 2014 in Minneapolis (MN, USA). This year's conference attracted over 400 attendants from around the world and featured over 100 presentations (46 oral) describing the role of SRS/SBRT for the treatment of intracranial and extracranial malignant and nonmalignant lesions. This article summarizes the meeting highlights for SRS/SBRT treatments, both intracranial and extracranial, in a concise review.

[Progress in methodological characteristics of clinical practice guideline for osteoarthritis].

PubMed

Xing, D; Wang, B; Lin, J H

2017-06-01

At present, several clinical practice guidelines for the treatment of osteoarthritis have been developed by institutes or societies. The ultimate purpose of developing clinical practice guidelines is to formulate the process in the treatment of osteoarthritis effectively. However, the methodologies used in developing clinical practice guidelines may place an influence on the transformation and application of that in treating osteoarthritis. The present study summarized the methodological features of individual clinical practice guideline and presented the tools for quality evaluation of clinical practice guideline. The limitations of current osteoarthritis guidelines of China are also indicated. The review article might help relevant institutions improve the quality in developing guide and clinical transformation.

User-Centered Collaborative Design and Development of an Inpatient Safety Dashboard.

PubMed

Mlaver, Eli; Schnipper, Jeffrey L; Boxer, Robert B; Breuer, Dominic J; Gershanik, Esteban F; Dykes, Patricia C; Massaro, Anthony F; Benneyan, James; Bates, David W; Lehmann, Lisa S

2017-12-01

Patient safety remains a key concern in hospital care. This article summarizes the iterative participatory development, features, functions, and preliminary evaluation of a patient safety dashboard for interdisciplinary rounding teams on inpatient medical services. This electronic health record (EHR)-embedded dashboard collects real-time data covering 13 safety domains through web services and applies logic to generate stratified alerts with an interactive check-box function. The technological infrastructure is adaptable to other EHR environments. Surveyed users perceived the tool as highly usable and useful. Integration of the dashboard into clinical care is intended to promote communication about patient safety and facilitate identification and management of safety concerns. Copyright © 2017 The Joint Commission. All rights reserved.

[Comorbidities as risk factors of chronic kidney disease in HIV-infected persons].

PubMed

Marchewka, Zofia; Szymczak, Aleksandra; Knysz, Brygida

2015-12-16

Significant survival prolongation in HIV-infected patients due to effective antiretroviral therapy is connected with increasing prevalence of chronic non-infective diseases in this population, among them chronic kidney disease. The pathogenesis of kidney disease in the setting of HIV includes conditions specific for HIV infection: direct effect of the virus, stage of immunodeficiency and drug toxicity. Chronic comorbidities, such as diabetes mellitus, hypertension, and hyperlipidemia, are additional significant risk factors of kidney disease. In HIV-infected individuals some distinct features of these conditions are observed, which are partly related to the virus and antiretroviral therapy. The article summarizes the effect of comorbidities on kidney function in HIV-infected persons.

Multifunctional Fluorescent-Magnetic Polymeric Colloidal Particles: Preparations and Bioanalytical Applications.

PubMed

Kaewsaneha, Chariya; Tangboriboonrat, Pramuan; Polpanich, Duangporn; Elaissari, Abdelhamid

2015-10-28

Fluorescent-magnetic particles (FMPs) play important roles in modern materials, especially as nanoscale devices in the biomedical field. The interesting features of FMPs are attributed to their dual detection ability, i.e., fluorescent and magnetic modes. Functionalization of FMPs can be performed using several types of polymers, allowing their use in various applications. The synergistic potentials for unique multifunctional, multilevel targeting nanoscale devices as well as combination therapies make them particularly attractive for biomedical applications. However, the synthesis of FMPs is challenging and must be further developed. In this review article, we summarized the most recent representative works on polymer-based FMP systems that have been applied particularly in the bioanalytical field.

Innovations in vaccine development: can regulatory authorities keep up?

PubMed

Cox, Manon M J; Onraedt, Annelies

2012-10-01

Vaccine Production Summit San Francisco, CA, USA, 4-6 June 2012 IBC's 3rd Vaccine Production Summit featured 28 presentations discussing regulatory challenges in vaccine development, including the use of adjuvants, vaccine manufacturing and technology transfer, process development for vaccines and the role of quality by design, how to address vaccine stability, and how vaccine development timelines can be improved. The conference was run in parallel with the single-use applications for Biopharmaceutical Manufacturing conference. Approximately 250 attendees from large pharmaceutical companies, large and small biotech companies, vendors and a more limited number from academia were allowed to access sessions of either conference, including one shared session. This article summarizes the recurring themes across various presentations.

Systematic Review and Meta-Analysis of CT Features for Differentiating Complicated and Uncomplicated Appendicitis.

PubMed

Kim, Hae Young; Park, Ji Hoon; Lee, Yoon Jin; Lee, Sung Soo; Jeon, Jong-June; Lee, Kyoung Ho

2018-04-01

Purpose To perform a systematic review and meta-analysis to identify computed tomographic (CT) features for differentiating complicated appendicitis in patients suspected of having appendicitis and to summarize their diagnostic accuracy. Materials and Methods Studies on diagnostic accuracy of CT features for differentiating complicated appendicitis (perforated or gangrenous appendicitis) in patients suspected of having appendicitis were searched in Ovid-MEDLINE, EMBASE, and the Cochrane Library. Overlapping descriptors used in different studies to denote the same image finding were subsumed under a single CT feature. Pooled diagnostic accuracy of the CT features was calculated by using a bivariate random effects model. CT features with pooled diagnostic odds ratios with 95% confidence intervals not including 1 were considered as informative. Results Twenty-three studies were included, and 184 overlapping descriptors for various CT findings were subsumed under 14 features. Of these, 10 features were informative for complicated appendicitis. There was a general tendency for these features to show relatively high specificity but low sensitivity. Extraluminal appendicolith, abscess, appendiceal wall enhancement defect, extraluminal air, ileus, periappendiceal fluid collection, ascites, intraluminal air, and intraluminal appendicolith showed pooled specificity greater than 70% (range, 74%-100%), but sensitivity was limited (range, 14%-59%). Periappendiceal fat stranding was the only feature that showed high sensitivity (94%; 95% confidence interval: 86%, 98%) but low specificity (40%; 95% confidence interval, 23%, 60%). Conclusion Ten informative CT features for differentiating complicated appendicitis were identified in this study, nine of which showed high specificity, but low sensitivity. © RSNA, 2017 Online supplemental material is available for this article.

The Use of Summarization Tasks: Some Lexical and Conceptual Analyses

ERIC Educational Resources Information Center

Yu, Guoxing

2013-01-01

This article reports the lexical diversity of summaries written by experts and test takers in an empirical study and then interrogates the (in)congruity between the conceptualisations of "summary" and "summarize" in the literature of educational research and the operationalization of summarization tasks in three international…

Bridging the Educational Research-Teaching Practice Gap: Curriculum Development, Part 1--Components of the Curriculum and Influences on the Process of Curriculum Design

ERIC Educational Resources Information Center

Anderson, Trevor R.; Rogan, John M.

2011-01-01

This article summarizes the major components of curriculum design: vision, operationalization of the vision, design, and evaluation. It stresses that the relationship between these components is dynamic, and that the process of curriculum design does not proceed via a linear application of these components. The article then summarizes some of the…

Progress in EEG-Based Brain Robot Interaction Systems

PubMed Central

Li, Mengfan; Niu, Linwei; Xian, Bin; Zeng, Ming; Chen, Genshe

2017-01-01

The most popular noninvasive Brain Robot Interaction (BRI) technology uses the electroencephalogram- (EEG-) based Brain Computer Interface (BCI), to serve as an additional communication channel, for robot control via brainwaves. This technology is promising for elderly or disabled patient assistance with daily life. The key issue of a BRI system is to identify human mental activities, by decoding brainwaves, acquired with an EEG device. Compared with other BCI applications, such as word speller, the development of these applications may be more challenging since control of robot systems via brainwaves must consider surrounding environment feedback in real-time, robot mechanical kinematics, and dynamics, as well as robot control architecture and behavior. This article reviews the major techniques needed for developing BRI systems. In this review article, we first briefly introduce the background and development of mind-controlled robot technologies. Second, we discuss the EEG-based brain signal models with respect to generating principles, evoking mechanisms, and experimental paradigms. Subsequently, we review in detail commonly used methods for decoding brain signals, namely, preprocessing, feature extraction, and feature classification, and summarize several typical application examples. Next, we describe a few BRI applications, including wheelchairs, manipulators, drones, and humanoid robots with respect to synchronous and asynchronous BCI-based techniques. Finally, we address some existing problems and challenges with future BRI techniques. PMID:28484488

Based on the development status of British BIM, exploring China’s BIM road

NASA Astrophysics Data System (ADS)

Tiangang, Chu; hui, Li; shanjun, Zhang; Ningshan, Jiang; Dan, Zhang; Yu, Zhang; Guibo, Bao

2018-05-01

This article mainly analyses the development and application status and development trend of BIM technology after the implementation of the British government, to explore the policies and methods that our government should carry out in the development of BIM. The article also summarizes and analyses the relevant policies and standards implemented by various provincial and municipal governments in promoting BIM technology in China and summarizes the strengths and weaknesses of each other by comparing the development status of the implementation of BIM policies in various provinces and cities. The article also analysed the obstacles encountered in the implementation of some specific projects at the current stage of BIM technology, and summarized the feasible solutions. The article mainly analyses the application prospects of BIM from the technical aspects of design, the application of technology in the construction process, and the strategic implementation and operation of the company, and provides a reference for promoting the application of BIM in the construction industry in China, especially in the western region.

Interface-Assisted Synthesis of 2D Materials: Trend and Challenges.

PubMed

Dong, Renhao; Zhang, Tao; Feng, Xinliang

2018-06-18

The discovery of graphene one decade ago has triggered enormous interest in developing two-dimensional materials (2DMs)-that is 2D allotropes of various elements or compounds (consisting of two or more covalently bonded elements) or molecular frameworks with periodic structures. At present, various synthesis strategies have been exploited to produce 2DMs, such as top-down exfoliation and bottom-up chemical vapor deposition and solution synthesis methods. In this review article, we will highlight the interfacial roles toward the controlled synthesis of inorganic and organic 2DMs with varied structural features. We will summarize the state-of-the-art progress on interfacial synthesis strategies and address their advancements in the structural, morphological, and crystalline control by the direction of the arrangement of the molecules or precursors at a confined 2D space. First, we will provide an overview of the interfaces and introduce their advantages and uniqueness for the synthesis of 2DMs, followed by a brief classification of inorganic and organic 2DMs achieved by interfacial synthesis. Next, the currently developed interfacial synthesis strategies combined with representative inorganic and organic 2DMs are summarized, including the description of method details, the corresponding structural features, and the insights into the advantages and limitations of the synthesis methods, along with some recommendable characterization methods for understanding the interfacial assembly of the precursors and crystal growth of 2DMs. After that, we will discuss several classes of emerging organic 2DMs with particular emphasis on the structural control by the interfacial synthesis strategies. Note that, inorganic 2DMs will not be categorized separately due to the fact that a number of review articles have covered the synthesis, structure, processing, and applications. Finally, the challenges and perspectives are provided regarding the future development of interface-assisted synthesis of 2DMs with diverse structural and functional control.

The Osborne 1.

ERIC Educational Resources Information Center

McWilliams, Peter

1982-01-01

Describes the unique features, available software, performance capabilities, system options, costs, advantages, disadvantages, and eccentricities of the Osborne 1 microcomputer. A table summarizes specifications, features, and costs. (JL)

Mucosal melanoma: a clinically and biologically unique disease entity.

PubMed

Carvajal, Richard D; Spencer, Sharon A; Lydiatt, William

2012-03-01

Mucosal melanoma (MM) is an aggressive and clinically complex malignancy made more challenging by its relative rarity. Because of the rarity of MM as a whole, and because of the unique biology and clinical challenges of MM arising from each anatomic location, understanding of this disease and its optimal management remains limited. The impact of various treatment strategies on disease control and survival has been difficult to assess because of the small size of most reported series of MM arising from any one particular site, the retrospective nature of most series, and the lack of a uniform comprehensive staging system for this disease. This article summarizes the clinical, pathologic, and molecular features, and the diagnostic and therapeutic considerations for the management of MM, underscoring the similarities and differences from cutaneous melanoma. Furthermore, the distinct clinical features and management implications unique to melanoma arising from the mucosal surfaces of the head and neck, the anorectal region, and the female genital tract are highlighted.

Local Anesthetic Systemic Toxicity: A Review of Recent Case Reports and Registries.

PubMed

Gitman, Marina; Barrington, Michael J

2018-02-01

This review summarizes presenting features, management, and outcomes of local anesthetic systemic toxicity (LAST) from published cases and those submitted to online registries capturing use of intravenous lipid emulsion (ILE) therapy. The results of single-center and multicenter registries and epidemiologic studies complement this information. Between March 2014 and November 2016, 47 separate cases of LAST were described in 35 peer-reviewed articles. Local anesthetic systemic toxicity events occurred as a result of penile blocks (23%), local infiltration (17%), and upper/lower extremity, torso, and neuraxial blockade. Twenty-two patients (47%) were treated with ILE, and 2 patients (4.3%) died. During the same time period, 11 cases submitted to lipidrescue.org were treated with ILE and survived. The incidence of LAST reported in registries is 0.03% or 0.27 (95% confidence interval, 0.21-0.35) per 1000 peripheral nerve blocks (denominator of 251,325). Seizure (53% and 61% from case reports and registries, respectively) was the most common presenting feature.

NCBI GEO: archive for high-throughput functional genomic data.

PubMed

Barrett, Tanya; Troup, Dennis B; Wilhite, Stephen E; Ledoux, Pierre; Rudnev, Dmitry; Evangelista, Carlos; Kim, Irene F; Soboleva, Alexandra; Tomashevsky, Maxim; Marshall, Kimberly A; Phillippy, Katherine H; Sherman, Patti M; Muertter, Rolf N; Edgar, Ron

2009-01-01

The Gene Expression Omnibus (GEO) at the National Center for Biotechnology Information (NCBI) is the largest public repository for high-throughput gene expression data. Additionally, GEO hosts other categories of high-throughput functional genomic data, including those that examine genome copy number variations, chromatin structure, methylation status and transcription factor binding. These data are generated by the research community using high-throughput technologies like microarrays and, more recently, next-generation sequencing. The database has a flexible infrastructure that can capture fully annotated raw and processed data, enabling compliance with major community-derived scientific reporting standards such as 'Minimum Information About a Microarray Experiment' (MIAME). In addition to serving as a centralized data storage hub, GEO offers many tools and features that allow users to effectively explore, analyze and download expression data from both gene-centric and experiment-centric perspectives. This article summarizes the GEO repository structure, content and operating procedures, as well as recently introduced data mining features. GEO is freely accessible at http://www.ncbi.nlm.nih.gov/geo/.

Attachment theory as a guide to understanding and working with transference and the real relationship in psychotherapy.

PubMed

Gelso, Charles J; Palma, Beatriz; Bhatia, Avantika

2013-11-01

Recent decades have witnessed an extraordinary amount of conceptual and empirical work on attachment theory in psychology and psychotherapy. Attachment theory is discussed in the present article as a way of understanding and fostering therapeutic work with 2 other key relationship constructs that have been theorized to be elements of all psychotherapies: client transference and the real relationship existing between the therapist and patient. Fundamental features of attachment, transference, and the real relationship are summarized. Particular emphasis is given to the role of the therapist as a secure base and a safe haven within the real relationship, and to the patient's internal working model as it relates to transference. A case of long-term psychodynamic psychotherapy conducted by the first author is presented to illuminate the 3 main constructs. The case demonstrates both the usefulness of attachment theory and the fact that any single theory cannot explain all of the complex features of a given treatment. © 2013 Wiley Periodicals, Inc.

Initial Archaeological Survey of the ex-USS Independence (CVL-22)

NASA Astrophysics Data System (ADS)

Delgado, James P.; Elliott, Kelley; Cantelas, Frank; Schwemmer, Robert V.

2016-04-01

The Boeing Company, collaborating with NOAA to address innovative ways to make ocean observations, provided their autonomous underwater vehicle, Echo Ranger, to conduct the first deep-water archaeological survey of the scuttled aircraft carrier USS Independence in the waters of Monterey Bay National Marine Sanctuary in March 2015. While a preliminary effort, and not comprehensive, the survey confirmed that a sonar feature (previously not proven to be an archaeological feature) charted at the location was Independence, and provided details on the condition of the wreck. At the same time, new information from declassified government reports provided more detail on Independence's use as a naval test craft for radiological decontamination as well as its use as a repository for radioactive materials at the time of its scuttling in 1951. The wreck is historically significant, but also of archaeological significance as an artifact of the early years of the atomic age and of the Cold War. This article summarizes Independence's contexts, its nuclear history, and the results of the survey of the wreck site.

Mycobacterium leprae–host-cell interactions and genetic determinants in leprosy: an overview

PubMed Central

Pinheiro, Roberta Olmo; de Souza Salles, Jorgenilce; Sarno, Euzenir Nunes; Sampaio, Elizabeth Pereira

2011-01-01

Leprosy, also known as Hansen’s disease, is a chronic infectious disease caused by Mycobacterium leprae in which susceptibility to the mycobacteria and its clinical manifestations are attributed to the host immune response. Even though leprosy prevalence has decreased dramatically, the high number of new cases indicates active transmission. Owing to its singular features, M. leprae infection is an attractive model for investigating the regulation of human immune responses to pathogen-induced disease. Leprosy is one of the most common causes of nontraumatic peripheral neuropathy worldwide. The proportion of patients with disabilities is affected by the type of leprosy and delay in diagnosis. This article briefly reviews the clinical features as well as the immunopathological mechanisms related to the establishment of the different polar forms of leprosy, the mechanisms related to M. leprae–host cell interactions and prophylaxis and diagnosis of this complex disease. Host genetic factors are summarized and the impact of the development of interventions that prevent, reverse or limit leprosy-related nerve impairments are discussed. PMID:21366421

Making Research Data Repositories Visible: The re3data.org Registry

PubMed Central

Pampel, Heinz; Vierkant, Paul; Scholze, Frank; Bertelmann, Roland; Kindling, Maxi; Klump, Jens; Goebelbecker, Hans-Jürgen; Gundlach, Jens; Schirmbacher, Peter; Dierolf, Uwe

2013-01-01

Researchers require infrastructures that ensure a maximum of accessibility, stability and reliability to facilitate working with and sharing of research data. Such infrastructures are being increasingly summarized under the term Research Data Repositories (RDR). The project re3data.org–Registry of Research Data Repositories–has begun to index research data repositories in 2012 and offers researchers, funding organizations, libraries and publishers an overview of the heterogeneous research data repository landscape. In July 2013 re3data.org lists 400 research data repositories and counting. 288 of these are described in detail using the re3data.org vocabulary. Information icons help researchers to easily identify an adequate repository for the storage and reuse of their data. This article describes the heterogeneous RDR landscape and presents a typology of institutional, disciplinary, multidisciplinary and project-specific RDR. Further the article outlines the features of re3data.org, and shows how this registry helps to identify appropriate repositories for storage and search of research data. PMID:24223762

Fluid Dynamics of Human Phonation and Speech

NASA Astrophysics Data System (ADS)

Mittal, Rajat; Erath, Byron D.; Plesniak, Michael W.

2013-01-01

This article presents a review of the fluid dynamics, flow-structure interactions, and acoustics associated with human phonation and speech. Our voice is produced through the process of phonation in the larynx, and an improved understanding of the underlying physics of this process is essential to advancing the treatment of voice disorders. Insights into the physics of phonation and speech can also contribute to improved vocal training and the development of new speech compression and synthesis schemes. This article introduces the key biomechanical features of the laryngeal physiology, reviews the basic principles of voice production, and summarizes the progress made over the past half-century in understanding the flow physics of phonation and speech. Laryngeal pathologies, which significantly enhance the complexity of phonatory dynamics, are discussed. After a thorough examination of the state of the art in computational modeling and experimental investigations of phonatory biomechanics, we present a synopsis of the pacing issues in this arena and an outlook for research in this fascinating subject.

Making research data repositories visible: the re3data.org Registry.

PubMed

Pampel, Heinz; Vierkant, Paul; Scholze, Frank; Bertelmann, Roland; Kindling, Maxi; Klump, Jens; Goebelbecker, Hans-Jürgen; Gundlach, Jens; Schirmbacher, Peter; Dierolf, Uwe

2013-01-01

Researchers require infrastructures that ensure a maximum of accessibility, stability and reliability to facilitate working with and sharing of research data. Such infrastructures are being increasingly summarized under the term Research Data Repositories (RDR). The project re3data.org-Registry of Research Data Repositories-has begun to index research data repositories in 2012 and offers researchers, funding organizations, libraries and publishers an overview of the heterogeneous research data repository landscape. In July 2013 re3data.org lists 400 research data repositories and counting. 288 of these are described in detail using the re3data.org vocabulary. Information icons help researchers to easily identify an adequate repository for the storage and reuse of their data. This article describes the heterogeneous RDR landscape and presents a typology of institutional, disciplinary, multidisciplinary and project-specific RDR. Further the article outlines the features of re3data.org, and shows how this registry helps to identify appropriate repositories for storage and search of research data.

[Analysis on acupuncture related articles published in periodicals in science citation index (SCI) in 2008].

PubMed

Wang, Chao; He, Wen-Ju; Guo, Yi

2010-09-01

Acupuncture related articles published in periodicals in Science Citation Index (SCI) in 2008 were summarized and analyzed. About 583 articles were collected using "acupuncture" and "in 2008" as keywords in the Web of Science data base by information retrieval. These papers were summarized and analyzed from various aspects of country, language, subject category, literature type, publication sources, impact factor, research method, acupoints, disease category and needling methods by using Excel software combined with manual sorting of the literature, the aim is to provide a reference for domestic acupuncture research.

Opinion mining feature-level using Naive Bayes and feature extraction based analysis dependencies

NASA Astrophysics Data System (ADS)

Sanda, Regi; Baizal, Z. K. Abdurahman; Nhita, Fhira

2015-12-01

Development of internet and technology, has major impact and providing new business called e-commerce. Many e-commerce sites that provide convenience in transaction, and consumers can also provide reviews or opinions on products that purchased. These opinions can be used by consumers and producers. Consumers to know the advantages and disadvantages of particular feature of the product. Procuders can analyse own strengths and weaknesses as well as it's competitors products. Many opinions need a method that the reader can know the point of whole opinion. The idea emerged from review summarization that summarizes the overall opinion based on sentiment and features contain. In this study, the domain that become the main focus is about the digital camera. This research consisted of four steps 1) giving the knowledge to the system to recognize the semantic orientation of an opinion 2) indentify the features of product 3) indentify whether the opinion gives a positive or negative 4) summarizing the result. In this research discussed the methods such as Naï;ve Bayes for sentiment classification, and feature extraction algorithm based on Dependencies Analysis, which is one of the tools in Natural Language Processing (NLP) and knowledge based dictionary which is useful for handling implicit features. The end result of research is a summary that contains a bunch of reviews from consumers on the features and sentiment. With proposed method, accuration for sentiment classification giving 81.2 % for positive test data, 80.2 % for negative test data, and accuration for feature extraction reach 90.3 %.

Curated Collection for Educators: Five Key Papers about the Flipped Classroom Methodology.

PubMed

King, Andrew; Boysen-Osborn, Megan; Cooney, Robert; Mitzman, Jennifer; Misra, Asit; Williams, Jennifer; Dulani, Tina; Gottlieb, Michael

2017-10-25

The flipped classroom (FC) pedagogy is becoming increasingly popular in medical education due to its appeal to the millennial learner and potential benefits in knowledge acquisition. Despite its popularity and effectiveness, the FC educational method is not without challenges. In this article, we identify and summarize several key papers relevant to medical educators interested in exploring the FC teaching methodology. The authors identified an extensive list of papers relevant to FC pedagogy via online discussions within the Academic Life in Emergency Medicine (ALiEM) Faculty Incubator. This list was augmented by an open call on Twitter (utilizing the #meded, #FOAMed, and #flippedclassroom hashtags) yielding a list of 33 papers. We then conducted a three-round modified Delphi process within the authorship group, which included both junior and senior clinician educators, to identify the most impactful papers for educators interested in FC pedagogy. The three-round modified Delphi process ranked all of the selected papers and selected the five most highly-rated papers for inclusion. The authorship group reviewed and summarized these papers with specific consideration given to their value to junior faculty educators and faculty developers interested in the flipped classroom approach. The list of papers featured in this article serves as a key reading list for junior clinician educators and faculty developers interested in the flipped classroom technique. The associated commentaries contextualize the importance of these papers for medical educators aiming to optimize their understanding and implementation of the flipped classroom methodology in their teaching and through faculty development.

Features of traffic and transit internet sites

DOT National Transportation Integrated Search

2000-02-01

This paper summarizes the current state of internet sites with respect to these features, first : considering whether sites with the features are available in metro areas, then comparing sites : developed by public and private sectors. In order to de...

Droxidopa in neurogenic orthostatic hypotension.

PubMed

Kaufmann, Horacio; Norcliffe-Kaufmann, Lucy; Palma, Jose-Alberto

2015-01-01

Neurogenic orthostatic hypotension (nOH) is a fall in blood pressure (BP) on standing due to reduced norepinephrine release from sympathetic nerve terminals. nOH is a feature of several neurological disorders that affect the autonomic nervous system, most notably Parkinson disease (PD), multiple system atrophy (MSA), pure autonomic failure (PAF), and other autonomic neuropathies. Droxidopa, an orally active synthetic amino acid that is converted to norepinephrine by the enzyme aromatic L-amino acid decarboxylase (dopa-decarboxylase), was recently approved by the FDA for the short-term treatment of nOH. It is presumed to raise BP by acting at the neurovascular junction to increase vascular tone. This article summarizes the pharmacological properties of droxidopa, its mechanism of action, and the efficacy and safety results of clinical trials.

The ALMT Family of Organic Acid Transporters in Plants and Their Involvement in Detoxification and Nutrient Security.

PubMed

Sharma, Tripti; Dreyer, Ingo; Kochian, Leon; Piñeros, Miguel A

2016-01-01

About a decade ago, members of a new protein family of anion channels were discovered on the basis of their ability to confer on plants the tolerance toward toxic aluminum ions in the soil. The efflux of Al 3+ -chelating malate anions through these channels is stimulated by external Al 3+ ions. This feature of a few proteins determined the name of the entire protein family as Aluminum-activated Malate Transporters (ALMT). Meanwhile, after several years of research, it is known that the physiological roles of ALMTs go far beyond Al-detoxification. In this review article we summarize the current knowledge on this transporter family and assess their involvement in diverse physiological processes.

The ALMT Family of Organic Acid Transporters in Plants and Their Involvement in Detoxification and Nutrient Security

PubMed Central

Sharma, Tripti; Dreyer, Ingo; Kochian, Leon; Piñeros, Miguel A.

2016-01-01

About a decade ago, members of a new protein family of anion channels were discovered on the basis of their ability to confer on plants the tolerance toward toxic aluminum ions in the soil. The efflux of Al3+-chelating malate anions through these channels is stimulated by external Al3+ ions. This feature of a few proteins determined the name of the entire protein family as Aluminum-activated Malate Transporters (ALMT). Meanwhile, after several years of research, it is known that the physiological roles of ALMTs go far beyond Al-detoxification. In this review article we summarize the current knowledge on this transporter family and assess their involvement in diverse physiological processes. PMID:27757118

Synthetic biodegradable functional polymers for tissue engineering: a brief review.

PubMed

BaoLin, Guo; Ma, Peter X

2014-04-01

Scaffolds play a crucial role in tissue engineering. Biodegradable polymers with great processing flexibility are the predominant scaffolding materials. Synthetic biodegradable polymers with well-defined structure and without immunological concerns associated with naturally derived polymers are widely used in tissue engineering. The synthetic biodegradable polymers that are widely used in tissue engineering, including polyesters, polyanhydrides, polyphosphazenes, polyurethane, and poly (glycerol sebacate) are summarized in this article. New developments in conducting polymers, photoresponsive polymers, amino-acid-based polymers, enzymatically degradable polymers, and peptide-activated polymers are also discussed. In addition to chemical functionalization, the scaffold designs that mimic the nano and micro features of the extracellular matrix (ECM) are presented as well, and composite and nanocomposite scaffolds are also reviewed.

Chinese Text Summarization Algorithm Based on Word2vec

NASA Astrophysics Data System (ADS)

Chengzhang, Xu; Dan, Liu

2018-02-01

In order to extract some sentences that can cover the topic of a Chinese article, a Chinese text summarization algorithm based on Word2vec is used in this paper. Words in an article are represented as vectors trained by Word2vec, the weight of each word, the sentence vector and the weight of each sentence are calculated by combining word-sentence relationship with graph-based ranking model. Finally the summary is generated on the basis of the final sentence vector and the final weight of the sentence. The experimental results on real datasets show that the proposed algorithm has a better summarization quality compared with TF-IDF and TextRank.

Differential Entropy Preserves Variational Information of Near-Infrared Spectroscopy Time Series Associated With Working Memory.

PubMed

Keshmiri, Soheil; Sumioka, Hidenubo; Yamazaki, Ryuji; Ishiguro, Hiroshi

2018-01-01

Neuroscience research shows a growing interest in the application of Near-Infrared Spectroscopy (NIRS) in analysis and decoding of the brain activity of human subjects. Given the correlation that is observed between the Blood Oxygen Dependent Level (BOLD) responses that are exhibited by the time series data of functional Magnetic Resonance Imaging (fMRI) and the hemoglobin oxy/deoxy-genation that is captured by NIRS, linear models play a central role in these applications. This, in turn, results in adaptation of the feature extraction strategies that are well-suited for discretization of data that exhibit a high degree of linearity, namely, slope and the mean as well as their combination, to summarize the informational contents of the NIRS time series. In this article, we demonstrate that these features are inefficient in capturing the variational information of NIRS data, limiting the reliability and the adequacy of the conclusion on their results. Alternatively, we propose the linear estimate of differential entropy of these time series as a natural representation of such information. We provide evidence for our claim through comparative analysis of the application of these features on NIRS data pertinent to several working memory tasks as well as naturalistic conversational stimuli.

Imaging of SHOX-associated anomalies.

PubMed

Gahunia, Harpal K; Babyn, Paul S; Kirsch, Susan; Mendoza-Londono, Roberto

2009-09-01

Human growth is a multifactorial trait influenced by environmental, hormonal, and genetic factors. Although it is clear that multiple factors contribute to an individual's final height and limb development, genetic factors play a crucial role. One such gene is the short stature homeobox ( SHOX) containing gene. Knowledge about the SHOX gene has rapidly increased since its discovery in 1997, and we now know that SHOX haploinsufficiency affects the development of the extremities and is an important cause of short stature. Currently, SHOX mutations occur with an estimated incidence of roughly 1 in 1000 newborns, making mutations of this gene one of the most common genetic defects associated with growth failure and skeletal deformities. Heterozygous mutations of SHOX have been implicated in patients with Madelung's deformity, Leri-Weill dyschondrosteosis (77%), Turner's syndrome (66%), and idiopathic short stature (3%), and homozygous mutations of SHOX gene have been identified in patients with Langer's mesomelic dysplasia (100%). Recognition of the early radiographic features encountered in SHOX haploinsufficiency maybe pivotal for the diagnosis. In this article, we summarize the genetic and clinical features of the various SHOX haploinsufficiency-associated disorders. We present the characteristic imaging features of these disorders and the results of growth hormone treatment trials.

MeSH indexing based on automatically generated summaries.

PubMed

Jimeno-Yepes, Antonio J; Plaza, Laura; Mork, James G; Aronson, Alan R; Díaz, Alberto

2013-06-26

MEDLINE citations are manually indexed at the U.S. National Library of Medicine (NLM) using as reference the Medical Subject Headings (MeSH) controlled vocabulary. For this task, the human indexers read the full text of the article. Due to the growth of MEDLINE, the NLM Indexing Initiative explores indexing methodologies that can support the task of the indexers. Medical Text Indexer (MTI) is a tool developed by the NLM Indexing Initiative to provide MeSH indexing recommendations to indexers. Currently, the input to MTI is MEDLINE citations, title and abstract only. Previous work has shown that using full text as input to MTI increases recall, but decreases precision sharply. We propose using summaries generated automatically from the full text for the input to MTI to use in the task of suggesting MeSH headings to indexers. Summaries distill the most salient information from the full text, which might increase the coverage of automatic indexing approaches based on MEDLINE. We hypothesize that if the results were good enough, manual indexers could possibly use automatic summaries instead of the full texts, along with the recommendations of MTI, to speed up the process while maintaining high quality of indexing results. We have generated summaries of different lengths using two different summarizers, and evaluated the MTI indexing on the summaries using different algorithms: MTI, individual MTI components, and machine learning. The results are compared to those of full text articles and MEDLINE citations. Our results show that automatically generated summaries achieve similar recall but higher precision compared to full text articles. Compared to MEDLINE citations, summaries achieve higher recall but lower precision. Our results show that automatic summaries produce better indexing than full text articles. Summaries produce similar recall to full text but much better precision, which seems to indicate that automatic summaries can efficiently capture the most important contents within the original articles. The combination of MEDLINE citations and automatically generated summaries could improve the recommendations suggested by MTI. On the other hand, indexing performance might be dependent on the MeSH heading being indexed. Summarization techniques could thus be considered as a feature selection algorithm that might have to be tuned individually for each MeSH heading.

Update in Hospice and Palliative Care.

PubMed

Gray, Nathan A; Horton, Jay R; Dionne-Odom, J Nicholas; Smith, Cardinale B; Johnson, Kimberly S

2016-05-01

The goal of this update in hospice and palliative care is to summarize and critique research published between January 1 and December 31, 2014 that has a high potential for impact on clinical practice. To identify articles we hand searched 22 leading journals, the Cochrane Database of Systematic Reviews, and Fast Article Critical Summaries for Clinicians in Palliative Care. We also performed a PubMed keyword search using the terms "hospice" and "palliative care." We ranked candidate articles based on study quality, appeal to a breadth of palliative care clinicians, and potential for impact on clinical practice. In this manuscript we have summarized the findings of eight articles with the highest ratings and make recommendations for clinical practice based on the strength of the resulting evidence.

Computer-aided prognosis on breast cancer with hematoxylin and eosin histopathology images: A review.

PubMed

Chen, Jia-Mei; Li, Yan; Xu, Jun; Gong, Lei; Wang, Lin-Wei; Liu, Wen-Lou; Liu, Juan

2017-03-01

With the advance of digital pathology, image analysis has begun to show its advantages in information analysis of hematoxylin and eosin histopathology images. Generally, histological features in hematoxylin and eosin images are measured to evaluate tumor grade and prognosis for breast cancer. This review summarized recent works in image analysis of hematoxylin and eosin histopathology images for breast cancer prognosis. First, prognostic factors for breast cancer based on hematoxylin and eosin histopathology images were summarized. Then, usual procedures of image analysis for breast cancer prognosis were systematically reviewed, including image acquisition, image preprocessing, image detection and segmentation, and feature extraction. Finally, the prognostic value of image features and image feature-based prognostic models was evaluated. Moreover, we discussed the issues of current analysis, and some directions for future research.

Global Emergency Medicine Journal Club: A Social Media Discussion About the Lack of Association Between Press Ganey Scores and Emergency Department Analgesia.

PubMed

Westafer, Lauren; Hensley, Justin; Shaikh, Sameed; Lin, Michelle

2016-01-01

Annals of Emergency Medicine collaborated with an educational Web site, Academic Life in Emergency Medicine (ALiEM), to host a public discussion featuring the 2014 Annals article on the association between Press Ganey scores and emergency department (ED) analgesia by Schwartz et al. The objective was to curate a 14-day (December 1 through 14, 2014) worldwide academic dialogue among clinicians in regard to preselected questions about the article. Five online facilitators hosted the multimodal discussion on the ALiEM Web site, Twitter, and Google Hangout. Comments across the social media platforms were curated for this report, as framed by the 4 preselected questions. Engagement was tracked through Web analytic tools and analysis of tweets. Blog comments, tweets, and video expert commentary involving the featured article are summarized and reported. The dialogue resulted in 978 page views from 342 cities in 33 countries on the ALiEM Web site, 464,345 Twitter impressions, and 83 views of the video interview with experts. Of the unique 169 identified tweets, discussion (53.3%) and learning points (32.5%) were the most common category of tweets identified. Common themes that arose in the open-access multimedia discussions included Press Ganey data validity and the utility of patient satisfaction in determining pain treatment efficacy. This educational approach using social media technologies demonstrates a free, asynchronous means to engage a worldwide scholarly discourse. Copyright © 2015 American College of Emergency Physicians. Published by Elsevier Inc. All rights reserved.

Panic disorder respiratory subtype: psychopathology, laboratory challenge tests, and response to treatment.

PubMed

Freire, Rafael C; Perna, Giampaolo; Nardi, Antonio E

2010-01-01

Our objective is to summarize the new findings concerning the respiratory subtype (RS) of panic disorder (PD) since its first description. Two searches were made in the Institute for Scientific Information Web of Science: with the keywords "panic disorder" and "respiratory symptoms," and all articles that cited Briggs and colleagues' 1993 article "Subtyping of Panic Disorder by Symptom Profile" (Br J Psychiatry 1993;163:201-9). Altogether, 133 articles were reviewed. We describe and discuss RS epidemiology, genetics, psychopathology, demographic features, clinical features, correlations with the respiratory system, traumatic suffocation history, provocative tests, and nocturnal panic. Compared to patients with the nonrespiratory subtype (non-RS), the RS patients had higher familial history of PD, lower comorbidity with depression, longer duration of illness, lower neuroticism scores, and higher scores in severity scales, such as the Panic and Agoraphobia Scale, Panic-Agoraphobia Spectrum scale and the Clinical Global Impression scale. Tests to induce panic attacks, such as those with CO(2), hyperventilation, and caffeine, produce panic attacks in a higher proportion of RS patients than non-RS patients. Differences in the subtypes' improvement with the pharmacologic treatment were found. There are also some controversial findings regarding the RS, including the age of onset of PD, and alcohol and tobacco use in RS patients. Some characteristics, such as the increased sensitivity to CO(2) and the higher familial history of PD, clearly distinguish the RS from the non-RS. Nevertheless, there are also controversial findings. More studies are needed to determine the validity of the RS subtype.

Authoring Newspaper Science Articles: A Rewarding Experience

ERIC Educational Resources Information Center

Gonzalez-Espada, Wilson J.

2009-01-01

In this article, the author summarizes the rationale for using science articles in K-16 education and addresses some of its limitations. The author also encourages scientists and college science faculty to contribute contextually relevant articles that might include selected literary techniques to their local or state newspapers.

[Summarization and analysis on the acupuncture-related articles published in science citation index (SCI) periodicals in 2005].

PubMed

Yang, Jia-Yue; Wu, Li-Ping; Guo, Yi

2007-04-01

To retrieve, summarize and analyze journals and articles related to acupuncture published in SCI periodicals in 2005, so as to understand the international dynamics about acupuncture researches. The articles about treatment and mechanisms of acupuncture published in SCI periodicals in 2005 were found out and searched for by acupuncture information retrieval online and databank. Most of the 72 SCI periodicals retrieved are from the west, with 147 articles of acupuncture published, and Lancet has the highest impact factors of 23. 407. The kinds of the journals and articles publishing acupuncture researches are increasing, with varied types, rich and varied contents, and increasing the design level. However, the results of the studies are vastly different due to differences of experimental methods, objects and acupuncture manipulations. Therefore, standardization of acupuncture studies is extremely urgent.

More than a "Basic Skill": Breaking down the Complexities of Summarizing for ABE/ESL Learners

ERIC Educational Resources Information Center

Ouellette-Schramm, Jennifer

2015-01-01

This article describes the complex cognitive and linguistic challenges of summarizing expository text at vocabulary, syntactic, and rhetorical levels. It then outlines activities to help ABE/ESL learners develop corresponding skills.

Handwriting Classification in Forensic Science.

ERIC Educational Resources Information Center

Ansell, Michael

1979-01-01

Considers systems for the classification of handwriting features, discusses computer storage of information about handwriting features, and summarizes recent studies that give an idea of the range of forensic handwriting research. (GT)

Review of cardiovascular imaging in the Journal of Nuclear Cardiology in 2017. Part 2 of 2: Myocardial perfusion imaging.

PubMed

Hage, Fadi G; AlJaroudi, Wael A

2018-04-16

In 2017, the Journal of Nuclear Cardiology published many high-quality articles. In this review, we will summarize a selection of these articles to provide a concise review of the main advancements that have recently occurred in the field. In the first article of this 2-part series, we focused on publications dealing with positron emission tomography, computed tomography, and magnetic resonance. This review will place emphasis on myocardial perfusion imaging using single-photon emission computed tomography summarizing advances in the field including prognosis, safety and tolerability, the impact of imaging on management, and the use of novel imaging protocols.

International regulations regarding exchange of Rubus plant material

USDA-ARS?s Scientific Manuscript database

This article summarizes the international quarantine regulations regarding plant material exchange for Rubus. US federal importation regulations are summarized along with aspects of Rubus that presented as noxious weed. Requirements for exporting Rubus to foreign countries are also described. Proper...

Research Summaries

ERIC Educational Resources Information Center

Brock, Stephen E., Ed.

2009-01-01

This article presents summaries of two recent crisis management publications: (1) "Social Validity of the CISM Model for School Crisis Intervention," summarized by Jack R. Dempsey; and (2) "School Violence: Associations With Control, Security/Enforcement, Educational/Therapeutic Approaches, and Demographic Factors," summarized by Ashlee Barton.…

Quantum caesium

DOE PAGES

Ansoborlo, Eric; Leggett, Richard Wayne

2015-03-24

This brief article summarizes the chemistry, history, applications, and hazards of caesium isotopes. The article is written for a general audience and will appear in the "In your element" section of Nature Chemistry.

Exploring supervised and unsupervised methods to detect topics in biomedical text

PubMed Central

Lee, Minsuk; Wang, Weiqing; Yu, Hong

2006-01-01

Background Topic detection is a task that automatically identifies topics (e.g., "biochemistry" and "protein structure") in scientific articles based on information content. Topic detection will benefit many other natural language processing tasks including information retrieval, text summarization and question answering; and is a necessary step towards the building of an information system that provides an efficient way for biologists to seek information from an ocean of literature. Results We have explored the methods of Topic Spotting, a task of text categorization that applies the supervised machine-learning technique naïve Bayes to assign automatically a document into one or more predefined topics; and Topic Clustering, which apply unsupervised hierarchical clustering algorithms to aggregate documents into clusters such that each cluster represents a topic. We have applied our methods to detect topics of more than fifteen thousand of articles that represent over sixteen thousand entries in the Online Mendelian Inheritance in Man (OMIM) database. We have explored bag of words as the features. Additionally, we have explored semantic features; namely, the Medical Subject Headings (MeSH) that are assigned to the MEDLINE records, and the Unified Medical Language System (UMLS) semantic types that correspond to the MeSH terms, in addition to bag of words, to facilitate the tasks of topic detection. Our results indicate that incorporating the MeSH terms and the UMLS semantic types as additional features enhances the performance of topic detection and the naïve Bayes has the highest accuracy, 66.4%, for predicting the topic of an OMIM article as one of the total twenty-five topics. Conclusion Our results indicate that the supervised topic spotting methods outperformed the unsupervised topic clustering; on the other hand, the unsupervised topic clustering methods have the advantages of being robust and applicable in real world settings. PMID:16539745

Degenerative Cervical Myelopathy: A Spectrum of Related Disorders Affecting the Aging Spine.

PubMed

Tetreault, Lindsay; Goldstein, Christina L; Arnold, Paul; Harrop, James; Hilibrand, Alan; Nouri, Aria; Fehlings, Michael G

2015-10-01

Cervical spinal cord dysfunction can result from either traumatic or nontraumatic causes, including tumors, infections, and degenerative changes. In this article, we review the range of degenerative spinal disorders resulting in progressive cervical spinal cord compression and propose the adoption of a new term, degenerative cervical myelopathy (DCM). DCM comprises both osteoarthritic changes to the spine, including spondylosis, disk herniation, and facet arthropathy (collectively referred to as cervical spondylotic myelopathy), and ligamentous aberrations such as ossification of the posterior longitudinal ligament and hypertrophy of the ligamentum flavum. This review summarizes current knowledge of the pathophysiology of DCM and describes the cascade of events that occur after compression of the spinal cord, including ischemia, destruction of the blood-spinal cord barrier, demyelination, and neuronal apoptosis. Important features of the diagnosis of DCM are discussed in detail, and relevant clinical and imaging findings are highlighted. Furthermore, this review outlines valuable assessment tools for evaluating functional status and quality of life in these patients and summarizes the advantages and disadvantages of each. Other topics of this review include epidemiology, the prevalence of degenerative changes in the asymptomatic population, the natural history and rates of progression, risk factors of diagnosis (clinical, imaging and genetic), and management strategies.

Article and process for producing an article

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lacy, Benjamin Paul; Jacala, Ariel Caesar Prepena; Kottilingam, Srikanth Chandrudu

An article and a process of producing an article are provided. The article includes a base material, a cooling feature arrangement positioned on the base material, the cooling feature arrangement including an additive-structured material, and a cover material. The cooling feature arrangement is between the base material and the cover material. The process of producing the article includes manufacturing a cooling feature arrangement by an additive manufacturing technique, and then positioning the cooling feature arrangement between a base material and a cover material.

A survey of simultaneous localization and mapping on unstructured lunar complex environment

NASA Astrophysics Data System (ADS)

Wang, Yiqiao; Zhang, Wei; An, Pei

2017-10-01

Simultaneous localization and mapping (SLAM) technology is the key to realizing lunar rover's intelligent perception and autonomous navigation. It embodies the autonomous ability of mobile robot, and has attracted plenty of concerns of researchers in the past thirty years. Visual sensors are meaningful to SLAM research because they can provide a wealth of information. Visual SLAM uses merely images as external information to estimate the location of the robot and construct the environment map. Nowadays, SLAM technology still has problems when applied in large-scale, unstructured and complex environment. Based on the latest technology in the field of visual SLAM, this paper investigates and summarizes the SLAM technology using in the unstructured complex environment of lunar surface. In particular, we focus on summarizing and comparing the detection and matching of features of SIFT, SURF and ORB, in the meanwhile discussing their advantages and disadvantages. We have analyzed the three main methods: SLAM Based on Extended Kalman Filter, SLAM Based on Particle Filter and SLAM Based on Graph Optimization (EKF-SLAM, PF-SLAM and Graph-based SLAM). Finally, this article summarizes and discusses the key scientific and technical difficulties in the lunar context that Visual SLAM faces. At the same time, we have explored the frontier issues such as multi-sensor fusion SLAM and multi-robot cooperative SLAM technology. We also predict and prospect the development trend of lunar rover SLAM technology, and put forward some ideas of further research.

Research Summaries

ERIC Educational Resources Information Center

Brock, Stephen E., Ed.

2009-01-01

This article presents summaries of four recent crisis management publications: (1) "Crisis Intervention for Children/Caregivers Exposed to Intimate Partner Violence," summarized by Donna DeVaughn Kreskey; (2) "Predictors of Trauma Reactions Following the 9/11 Terrorist Attacks," summarized by Kelly O'Connor; (3) "Cognitive Coping Styles and PTSD…

Interactive molecular dynamics

NASA Astrophysics Data System (ADS)

Schroeder, Daniel V.

2015-03-01

Physics students now have access to interactive molecular dynamics simulations that can model and animate the motions of hundreds of particles, such as noble gas atoms, that attract each other weakly at short distances but repel strongly when pressed together. Using these simulations, students can develop an understanding of forces and motions at the molecular scale, nonideal fluids, phases of matter, thermal equilibrium, nonequilibrium states, the Boltzmann distribution, the arrow of time, and much more. This article summarizes the basic features and capabilities of such a simulation, presents a variety of student exercises using it at the introductory and intermediate levels, and describes some enhancements that can further extend its uses. A working simulation code, in html5 and javascript for running within any modern Web browser, is provided as an online supplement.

Interplay between coagulation and vascular inflammation in sickle cell disease

PubMed Central

Sparkenbaugh, Erica; Pawlinski, Rafal

2013-01-01

Sickle cell disease is the most common inherited hematologic disorder that leads to the irreversible damage of multiple organs. Although sickling of red blood cells and vaso-occlusion are central to the pathophysiology of sickle cell disease the importance of hemolytic anemia and vasculopathy has been recently recognized. Hypercoagulation state is another prominent feature of sickle cell disease and is mediated by activation of both intrinsic and extrinsic coagulation pathways. Growing evidence demonstrates that coagulation may not only contribute to the thrombotic complications, but also to vascular inflammation associated with this disease. This article summarizes the role of vascular inflammation and coagulation activation, discusses potential mechanisms responsible for activation of coagulation and reviews recent data demonstrating the crosstalk between coagulation and vascular inflammation in sickle cell disease. PMID:23593937

I've got you under my skin: narratives of the inner body in cinema and television.

PubMed

Brodesco, Alberto

2011-01-01

1966 Twentieth Century Fox big-budget film Fantastic Voyage represents a corner stone around which a whole audiovisual trope was built. The topic of the voyage of shrunken people sent to explore the inner space of the body was adopted since then by many feature films, television series and animated TV series, for the aims of education, entertainment or edutainment. While the exploration of the body (and, often, the meeting with its inhabitants) gives space to just a few possibilities of plot development, it leaves open ground for metaphors. Starting from the hypotext, this article analyzes a sample of audiovisuals to try to summarize a taxonomy of narrative schemes and the different metaphors (and their uses) that our body can host.

Oncolytic Poxviruses

PubMed Central

Chan, Winnie M.; McFadden, Grant

2015-01-01

Current standard treatments of cancer can prolong survival of many cancer patients but usually do not effectively cure the disease. Oncolytic virotherapy is an emerging therapeutic for the treatment of cancer that exploits replication-competent viruses to selectively infect and destroy cancerous cells while sparing normal cells and tissues. Clinical and/or preclinical studies on oncolytic viruses have revealed that the candidate viruses being tested in trials are remarkably safe and offer potential for treating many classes of currently incurable cancers. Among these candidates are vaccinia and myxoma viruses, which belong to the family Poxviridae and possess promising oncolytic features. This article describes poxviruses that are being developed for oncolytic virotherapy and summarizes the outcomes of both clinical and preclinical studies. Additionally, studies demonstrating superior efficacy when poxvirus oncolytic virotherapy is combined with conventional therapies are described. PMID:25839047

Pre-Test Analysis Predictions for the Shell Buckling Knockdown Factor Checkout Tests - TA01 and TA02

NASA Technical Reports Server (NTRS)

Thornburgh, Robert P.; Hilburger, Mark W.

2011-01-01

This report summarizes the pre-test analysis predictions for the SBKF-P2-CYL-TA01 and SBKF-P2-CYL-TA02 shell buckling tests conducted at the Marshall Space Flight Center (MSFC) in support of the Shell Buckling Knockdown Factor (SBKF) Project, NASA Engineering and Safety Center (NESC) Assessment. The test article (TA) is an 8-foot-diameter aluminum-lithium (Al-Li) orthogrid cylindrical shell with similar design features as that of the proposed Ares-I and Ares-V barrel structures. In support of the testing effort, detailed structural analyses were conducted and the results were used to monitor the behavior of the TA during the testing. A summary of predicted results for each of the five load sequences is presented herein.

Clarifying the abstracts of systematic literature reviews*

PubMed Central

Hartley, James

2000-01-01

Background: There is a small body of research on improving the clarity of abstracts in general that is relevant to improving the clarity of abstracts of systematic reviews. Objectives: To summarize this earlier research and indicate its implications for writing the abstracts of systematic reviews. Method: Literature review with commentary on three main features affecting the clarity of abstracts: their language, structure, and typographical presentation. Conclusions: The abstracts of systematic reviews should be easier to read than the abstracts of medical research articles, as they are targeted at a wider audience. The aims, methods, results, and conclusions of systematic reviews need to be presented in a consistent way to help search and retrieval. The typographic detailing of the abstracts (type-sizes, spacing, and weights) should be planned to help, rather than confuse, the reader. PMID:11055300

Personalized Nanoparticles for Cancer Therapy: A Call for Greater Precision.

PubMed

Sahakyan, Nare; Haddad, Amir; Richardson, Shye; Forcha-Etieundem, Valery; Christopher, Lee; Alharbi, Hanan; Campbell, Robert

2017-01-01

Nanotechnology has brought about the advent of personalized medicine in the era of targeted therapeutic strategies for cancer therapy. The ability to exploit tumor features for therapeutic gain has made it possible to manufacture more effective nanomedicines for cancer treatment. However, known obstacles, including the inability to overcome pathophysiological barriers of tumors, have impeded disease management. In spite of this, recent efforts have been made to develop more functionalized nanosystems that utilize the active-targeting approach. This article reviews the FDA-approved cancer drug delivery systems in the general framework of personalized nanomedicine. We discuss the latest efforts in the development of functionalized nano-systems, and summarize relevant ongoing preclinical and clinical trials. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Management of Crush Syndrome Casualties after Disasters

PubMed Central

Sever, Mehmet Sukru; Vanholder, Raymond

2011-01-01

After direct impact of the trauma, crush syndrome is the second most frequent cause of death after mass disasters. However, since crush syndrome is quite rare in daily practice, mistakes are frequent in the treatment of these cases. This paper summarizes the etiopathogenesis of traumatic rhabdomyolysis and of crush syndrome-based acute kidney injury. The clinical and laboratory features, prophylaxis, and treatment of crush cases are described as well. The importance of early and energetic fluid resuscitation is underlined for prophylaxis of acute kidney injury. Since there is chaos, and an overwhelming number of victims, logistic drawbacks create a specific problem in the treatment of crush victims after mass disasters. Potential solutions for logistic hurdles and disaster preparedness scenarios have also been provided in this review article. PMID:23908797

Quebec platelet disorder.

PubMed

Hayward, Catherine P M; Rivard, Georges E

2011-04-01

Quebec platelet disorder (QPD) is an autosomal dominant bleeding disorder associated with a unique gain-of-function defect in fibrinolysis. In the past 5 years, there have been important advances in the understanding of the pathogenesis of QPD, including its genetic cause, which is a copy number variation mutation of PLAU, the gene for urokinase plasminogen activator (uPA). QPD is the first bleeding disorder identified to be caused by a PLAU mutation and it is also the first bleeding disorder recognized to result from a gene copy number mutation. The molecular defect of QPD leads to marked overexpression of uPA during megakaryopoiesis, producing profibrinolytic platelets that contain active forms of uPA in their α-granules. This article summarizes expert opinions on the features of QPD and recent advances in the understanding of its pathogenesis and genetic cause.

Cholesterol Point-of-Care Testing for Community Pharmacies: A Review of the Current Literature.

PubMed

Haggerty, Lauren; Tran, Deanna

2017-08-01

To summarize the literature on cholesterol point-of-care tests (POCTs). This article would serve as a resource to assist community pharmacists in developing cholesterol point-of-care (POC) pharmacy services. A literature search was performed in MEDLINE Ovid, PubMed, EMBASE, and Cochrane database using the following medical subject headings (MeSH) terms: point-of-care test, cholesterol, blood chemical analysis, rapid testing, collaborative practice, community pharmacy, and ambulatory care. Additional resources including device manufacturer web sites were summarized to supplement the current literature. All human research articles, review articles, meta-analyses, and abstracts published in English through September 1, 2014, were considered. A total of 36 articles were applicable for review. Information was divided into the following categories to be summarized: devices, pharmacists' impact, and operational cost for the pharmacy. The current literature suggests that POCTs in community pharmacies assist with patient outcomes by providing screenings and referring patients with dyslipidemia for further evaluation. The majority of studies on cholesterol POC devices focused on accuracy, revealing the need for further studies to develop best practices and practice models with successful reimbursement. Accuracy, device specifications, required supplies, and patient preference should be considered when selecting a POC device for purchase.

Data on the descriptive overview and the quality assessment details of 12 qualitative research papers.

PubMed

Barnabishvili, Maia; Ulrichs, Timo; Waldherr, Ruth

2016-09-01

This data article presents the supplementary material for the review paper "Role of acceptability barriers in delayed diagnosis of Tuberculosis: Literature review from high burden countries" (Barnabishvili et al., in press) [1]. General overview of 12 qualitative papers, including the details about authors, years of publication, data source locations, study objectives, overview of methods, study population characteristics, as well as the details of intervention and the outcome parameters of the papers are summarized in the first two tables included to the article. Quality assessment process of the methodological strength of 12 papers and the results of the critical appraisal are further described and summarized in the second part of the article.

Regime shifts and panarchies in regional scale social-ecological water systems

PubMed Central

Gunderson, Lance; Cosens, Barbara A.; Chaffin, Brian C.; (Tom) Arnold, Craig A.; Fremier, Alexander K.; Garmestani, Ahjond S.; Craig, Robin Kundis; Gosnell, Hannah; Birge, Hannah E.; Allen, Craig R.; Benson, Melinda H.; Morrison, Ryan R.; Stone, Mark C.; Hamm, Joseph A.; Nemec, Kristine; Schlager, Edella; Llewellyn, Dagmar

2018-01-01

In this article we summarize histories of nonlinear, complex interactions among societal, legal, and ecosystem dynamics in six North American water basins, as they respond to changing climate. These case studies were chosen to explore the conditions for emergence of adaptive governance in heavily regulated and developed social-ecological systems nested within a hierarchical governmental system. We summarize resilience assessments conducted in each system to provide a synthesis and reference by the other articles in this special feature. We also present a general framework used to evaluate the interactions between society and ecosystem regimes and the governance regimes chosen to mediate those interactions. The case studies show different ways that adaptive governance may be triggered, facilitated, or constrained by ecological and/or legal processes. The resilience assessments indicate that complex interactions among the governance and ecosystem components of these systems can produce different trajectories, which include patterns of (a) development and stabilization, (b) cycles of crisis and recovery, which includes lurches in adaptation and learning, and (3) periods of innovation, novelty, and transformation. Exploration of cross scale (Panarchy) interactions among levels and sectors of government and society illustrate that they may constrain development trajectories, but may also provide stability during crisis or innovation at smaller scales; create crises, but may also facilitate recovery; and constrain system transformation, but may also provide windows of opportunity in which transformation, and the resources to accomplish it, may occur. The framework is the starting point for our exploration of how law might play a role in enhancing the capacity of social-ecological systems to adapt to climate change. PMID:29780427

Regime shifts and panarchies in regional scale social-ecological water systems.

PubMed

Gunderson, Lance; Cosens, Barbara A; Chaffin, Brian C; Tom Arnold, Craig A; Fremier, Alexander K; Garmestani, Ahjond S; Craig, Robin Kundis; Gosnell, Hannah; Birge, Hannah E; Allen, Craig R; Benson, Melinda H; Morrison, Ryan R; Stone, Mark C; Hamm, Joseph A; Nemec, Kristine; Schlager, Edella; Llewellyn, Dagmar

2017-03-17

In this article we summarize histories of nonlinear, complex interactions among societal, legal, and ecosystem dynamics in six North American water basins, as they respond to changing climate. These case studies were chosen to explore the conditions for emergence of adaptive governance in heavily regulated and developed social-ecological systems nested within a hierarchical governmental system. We summarize resilience assessments conducted in each system to provide a synthesis and reference by the other articles in this special feature. We also present a general framework used to evaluate the interactions between society and ecosystem regimes and the governance regimes chosen to mediate those interactions. The case studies show different ways that adaptive governance may be triggered, facilitated, or constrained by ecological and/or legal processes. The resilience assessments indicate that complex interactions among the governance and ecosystem components of these systems can produce different trajectories, which include patterns of (a) development and stabilization, (b) cycles of crisis and recovery, which includes lurches in adaptation and learning, and (3) periods of innovation, novelty, and transformation. Exploration of cross scale (Panarchy) interactions among levels and sectors of government and society illustrate that they may constrain development trajectories, but may also provide stability during crisis or innovation at smaller scales; create crises, but may also facilitate recovery; and constrain system transformation, but may also provide windows of opportunity in which transformation, and the resources to accomplish it, may occur. The framework is the starting point for our exploration of how law might play a role in enhancing the capacity of social-ecological systems to adapt to climate change.

Regime shifts and panarchies in regional scale social-ecological water systems

USGS Publications Warehouse

Gunderson, Lance; Cosens, Barbara; Chaffin, Brian C.; Arnold, Craig Anthony (Tony); Fremier, Alexander K.; Garmestani, Ahjond S.; Kundis Craig, Robin; Gosnell, Hannah; Birge, Hannah E.; Allen, Craig R.; Benson, Melinda H.; Morrison, Ryan R.; Stone, Mark; Hamm, Joseph A.; Nemec, Kristine T.; Schlager, Edella; Llewellyn, Dagmar

2017-01-01

In this article we summarize histories of nonlinear, complex interactions among societal, legal, and ecosystem dynamics in six North American water basins, as they respond to changing climate. These case studies were chosen to explore the conditions for emergence of adaptive governance in heavily regulated and developed social-ecological systems nested within a hierarchical governmental system. We summarize resilience assessments conducted in each system to provide a synthesis and reference by the other articles in this special feature. We also present a general framework used to evaluate the interactions between society and ecosystem regimes and the governance regimes chosen to mediate those interactions. The case studies show different ways that adaptive governance may be triggered, facilitated, or constrained by ecological and/or legal processes. The resilience assessments indicate that complex interactions among the governance and ecosystem components of these systems can produce different trajectories, which include patterns of (a) development and stabilization, (b) cycles of crisis and recovery, which includes lurches in adaptation and learning, and (3) periods of innovation, novelty, and transformation. Exploration of cross scale (Panarchy) interactions among levels and sectors of government and society illustrate that they may constrain development trajectories, but may also provide stability during crisis or innovation at smaller scales; create crises, but may also facilitate recovery; and constrain system transformation, but may also provide windows of opportunity in which transformation, and the resources to accomplish it, may occur. The framework is the starting point for our exploration of how law might play a role in enhancing the capacity of social-ecological systems to adapt to climate change.

Curated Collection for Educators: Five Key Papers about the Flipped Classroom Methodology

PubMed Central

Boysen-Osborn, Megan; Cooney, Robert; Mitzman, Jennifer; Misra, Asit; Williams, Jennifer; Dulani, Tina; Gottlieb, Michael

2017-01-01

The flipped classroom (FC) pedagogy is becoming increasingly popular in medical education due to its appeal to the millennial learner and potential benefits in knowledge acquisition. Despite its popularity and effectiveness, the FC educational method is not without challenges. In this article, we identify and summarize several key papers relevant to medical educators interested in exploring the FC teaching methodology. The authors identified an extensive list of papers relevant to FC pedagogy via online discussions within the Academic Life in Emergency Medicine (ALiEM) Faculty Incubator. This list was augmented by an open call on Twitter (utilizing the #meded, #FOAMed, and #flippedclassroom hashtags) yielding a list of 33 papers. We then conducted a three-round modified Delphi process within the authorship group, which included both junior and senior clinician educators, to identify the most impactful papers for educators interested in FC pedagogy. The three-round modified Delphi process ranked all of the selected papers and selected the five most highly-rated papers for inclusion. The authorship group reviewed and summarized these papers with specific consideration given to their value to junior faculty educators and faculty developers interested in the flipped classroom approach. The list of papers featured in this article serves as a key reading list for junior clinician educators and faculty developers interested in the flipped classroom technique. The associated commentaries contextualize the importance of these papers for medical educators aiming to optimize their understanding and implementation of the flipped classroom methodology in their teaching and through faculty development. PMID:29282445

Features of a Mobile Support App for Patients With Chronic Obstructive Pulmonary Disease: Literature Review and Current Applications

PubMed Central

Philip, Nada; Kayyali, Reem; Nabhani-Gebara, Shereen; Pierscionek, Barbara; Vaes, Anouk W; Spruit, Martijn A; Kaimakamis, Evangelos

2017-01-01

Background Chronic obstructive pulmonary disease (COPD) is a serious long-term lung disease in which the airflow from the lungs is progressively reduced. By 2030, COPD will become the third cause of mortality and seventh cause of morbidity worldwide. With advances in technology and mobile communications, significant progress in the mobile health (mHealth) sector has been recently observed. Mobile phones with app capabilities (smartphones) are now considered as potential media for the self-management of certain types of diseases such as asthma, cancer, COPD, or cardiovascular diseases. While many mobile apps for patients with COPD are currently found on the market, there is little published material on the effectiveness of most of them, their features, and their adoption in health care settings. Objectives The aim of this study was to search the literature for current systems related to COPD and identify any missing links and studies that were carried out to evaluate the effectiveness of COPD mobile apps. In addition, we reviewed existing mHealth apps from different stores in order to identify features that can be considered in the initial design of a COPD support tool to improve health care services and patient outcomes. Methods In total, 206 articles related to COPD management systems were identified from different databases. Irrelevant materials and duplicates were excluded. Of those, 38 articles were reviewed to extract important features. We identified 214 apps from online stores. Following exclusion of irrelevant apps, 48 were selected and 20 of them were downloaded to review some of their common features. Results Our review found that out of the 20 apps downloaded, 13 (65%, 13/20) had an education section, 5 (25%, 5/20) consisted of medication and guidelines, 6 (30%, 6/20) included a calendar or diary and other features such as reminders or symptom tracking. There was little published material on the effectiveness of the identified COPD apps. Features such as (1) a social networking tool; (2) personalized education; (3) feedback; (4) e-coaching; and (5) psychological motivation to enhance behavioral change were found to be missing in many of the downloaded apps. Conclusions This paper summarizes the features of a COPD patient-support mobile app that can be taken into consideration for the initial design of an integrated care system to encourage the self-management of their condition at home. PMID:28219878

A scoping review of cloud computing in healthcare.

PubMed

Griebel, Lena; Prokosch, Hans-Ulrich; Köpcke, Felix; Toddenroth, Dennis; Christoph, Jan; Leb, Ines; Engel, Igor; Sedlmayr, Martin

2015-03-19

Cloud computing is a recent and fast growing area of development in healthcare. Ubiquitous, on-demand access to virtually endless resources in combination with a pay-per-use model allow for new ways of developing, delivering and using services. Cloud computing is often used in an "OMICS-context", e.g. for computing in genomics, proteomics and molecular medicine, while other field of application still seem to be underrepresented. Thus, the objective of this scoping review was to identify the current state and hot topics in research on cloud computing in healthcare beyond this traditional domain. MEDLINE was searched in July 2013 and in December 2014 for publications containing the terms "cloud computing" and "cloud-based". Each journal and conference article was categorized and summarized independently by two researchers who consolidated their findings. 102 publications have been analyzed and 6 main topics have been found: telemedicine/teleconsultation, medical imaging, public health and patient self-management, hospital management and information systems, therapy, and secondary use of data. Commonly used features are broad network access for sharing and accessing data and rapid elasticity to dynamically adapt to computing demands. Eight articles favor the pay-for-use characteristics of cloud-based services avoiding upfront investments. Nevertheless, while 22 articles present very general potentials of cloud computing in the medical domain and 66 articles describe conceptual or prototypic projects, only 14 articles report from successful implementations. Further, in many articles cloud computing is seen as an analogy to internet-/web-based data sharing and the characteristics of the particular cloud computing approach are unfortunately not really illustrated. Even though cloud computing in healthcare is of growing interest only few successful implementations yet exist and many papers just use the term "cloud" synonymously for "using virtual machines" or "web-based" with no described benefit of the cloud paradigm. The biggest threat to the adoption in the healthcare domain is caused by involving external cloud partners: many issues of data safety and security are still to be solved. Until then, cloud computing is favored more for singular, individual features such as elasticity, pay-per-use and broad network access, rather than as cloud paradigm on its own.

Spanish Heart Transplant Registry. 28th Official Report of the Spanish Society of Cardiology Working Group on Heart Failure (1984-2016).

PubMed

González-Vílchez, Francisco; Gómez-Bueno, Manuel; Almenar-Bonet, Luis; Crespo-Leiro, María G; Arizón Del Prado, José M; Delgado-Jiménez, Juan; Sousa-Casasnovas, Iago; Brossa-Loidi, Vicens; Sobrino-Márquez, José Manuel; González-Costelo, José

2017-12-01

The present article reports the characteristics and results of heart transplants in Spain since this therapeutic modality was first used in May 1984. We summarize the main features of recipients, donors, surgical procedures, and outcomes of all cardiac transplants performed in Spain up to December 31, 2016. A total of 281 cardiac transplants were performed in 2016. The whole historical series consisted of 7869 procedures. The main features of transplant procedures in 2016 were similar to those observed in recent years. A high percentage of procedures were urgent, particularly those with use of pretransplant continuous-flow left ventricular assist devices (19.1% of all transplants). Survival significantly improved in the last decade compared with previous periods. During the last few years, transplant activity in Spain has remained steady, with approximately 250-300 transplants/year. Despite a more complex clinical context, survival has improved in recent years. Copyright © 2017 Sociedad Española de Cardiología. Published by Elsevier España, S.L.U. All rights reserved.

Thermal stability of gallium arsenide solar cells

NASA Astrophysics Data System (ADS)

Papež, Nikola; Škvarenina, Ľubomír.; Tofel, Pavel; Sobola, Dinara

2017-12-01

This article summarizes a measurement of gallium arsenide (GaAs) solar cells during their thermal processing. These solar cells compared to standard silicon cells have better efficiency and high thermal stability. However, their use is partly limited due to high acquisition costs. For these reasons, GaAs cells are deployed only in the most demanding applications where their features are needed, such as space applications. In this work, GaAs solar cells were studied in a high temperature range within 30-650 °C where their functionality and changes in surface topology were monitored. These changes were recorded using an electron microscope which determined the position of the defects; using an atomic force microscope we determined the roughness of the surface and an infrared camera that showed us the thermal radiated places of the defected parts of the cell. The electrical characteristics of the cells during processing were determined by its current-voltage characteristics. Despite the occurrence of subtle changes on the solar cell with newly created surface features after 300 °C thermal processing, its current-voltage characteristic remained without a significant change.

Crisis Management Research Summaries

ERIC Educational Resources Information Center

Brock, Stephen E., Ed.

2009-01-01

In this column, Crisis Management in the Schools Interest Group members summarize recent crisis management publications. The first article summarized was a meta-analysis of the risk factors associated with Posttraumatic Stress Disorder (PTSD) among adults. The second study looked at the presence of life stressors among students who were expelled…

Transforming AdaPT to Ada

NASA Technical Reports Server (NTRS)

Goldsack, Stephen J.; Holzbach-Valero, A. A.; Waldrop, Raymond S.; Volz, Richard A.

1991-01-01

This paper describes how the main features of the proposed Ada language extensions intended to support distribution, and offered as possible solutions for Ada9X can be implemented by transformation into standard Ada83. We start by summarizing the features proposed in a paper (Gargaro et al, 1990) which constitutes the definition of the extensions. For convenience we have called the language in its modified form AdaPT which might be interpreted as Ada with partitions. These features were carefully chosen to provide support for the construction of executable modules for execution in nodes of a network of loosely coupled computers, but flexibly configurable for different network architectures and for recovery following failure, or adapting to mode changes. The intention in their design was to provide extensions which would not impact adversely on the normal use of Ada, and would fit well in style and feel with the existing standard. We begin by summarizing the features introduced in AdaPT.

Carpal Tunnel Syndrome: Symptoms, Causes and Treatment Options. Literature Reviev.

PubMed

Zamborsky, Radoslav; Kokavec, Milan; Simko, Lukas; Bohac, Martin

2017-01-26

Carpal Tunnel Syndrome (CTS) is the most common form of entrapment neuropathy. Several authors have investigated the anatomical and pathophysiological features of CTS and have identified several parameters that, in combination, play a significant role in its pathophysiology. Advancement in biological research on CTS has enabled the advent of efficient diagnostic techniques such as provocative tests and nerve conduction studies. Sophisticated technologies, such as magnetic resonance imaging (MRI) and ultrasonography (US), have facilitated the diagnosis of CTS. This review article aims at consolidating the relevant medical literature pertaining to the symptoms, pathophysiology, clinical diagnosis and treatment strategies of CTS. It also compares the various methods of diagnosis and discusses their benefits and disadvantages. Finally, it sheds light on the conservative vs. surgical approach to treatment and compares them. While the surgical approach has proved to be more efficient relative to the conservative methods of steroid injections and splinting, many studies have demonstrated both advantages and adverse effects of the surgical methods. Surgical options and complications are discussed in detail. This article comprehensively summarizes all medical aspects of CTS to update medical professionals' knowledge regarding the disease.

Methaemoglobinaemia associated with the use of cocaine and volatile nitrites as recreational drugs: a review

PubMed Central

Hunter, Laura; Gordge, Laura; Dargan, Paul I; Wood, David M

2011-01-01

Methaemoglobinaemia can cause significant tissue hypoxia, leading to severe, potentially life-threatening clinical features and/or death. Over recent years there have been increasing reports of methaemoglobinaemia related to recreational drug use. There have been 25 articles describing methaemoglobinaemia related to recreational use of volatile nitrites (poppers) and more recently, four reports of methaemoglobinaemia in association with recreational cocaine use. In this article we discuss the mechanisms by which methaemoglobinaemia occurs in relation to the use of both volatile nitrites and cocaine, and summarize the published cases of recreational drug-related methaemoglobinaemia. The volatile nitrites can cause methaemoglobinaemia directly through their activity as oxidizing agents. However, with cocaine, methaemoglobinaemia is related to adulterants such as local anaesthetics or phenacetin, rather than to the cocaine itself. Clinicians managing patients with acute recreational drug toxicity should be aware of the potential for methaemoglobinaemia in these patients, particularly in patients with cyanosis or unexplained low oxygen saturations on pulse oximetry, and ensure that appropriate and timely management is provided, including, where appropriate, the use of methylthioninium chloride (methylene blue). PMID:21352269

Adverse CNS-effects of beta-adrenoceptor blockers.

PubMed

Gleiter, C H; Deckert, J

1996-11-01

In 1962 propranolol, the first beta adrenoceptor antagonist (beta blocker), was brought on to the market. There is now a host of different beta blockers available, and these compounds are among the most commonly prescribed groups of drugs. The efficacy of beta blockers has been proven predominantly for the treatment of cardiovascular diseases. Beta blockers are also used for certain types of CNS disorders, such as anxiety disorders, essential tremor and migraine. While low toxicity means that they have a favorable risk-benefit ratio, given the high intensity of use, it is essential to have a comprehensive knowledge of adverse events. Adverse events of beta blockers that can be related to the CNS are quite often neglected, even in textbooks of clinical pharmacology or review articles, and thus often misdiagnosed. The following article, therefore, after summarizing the use of beta blockers for CNS indications, critically reviews the literature on centrally mediated adverse events. General pharmacological features of beta blockers and their molecular basis of action will briefly be addressed to the extent that they are or may become relevant for central nervous pharmacotherapy and side-effects.

Towards pervasive computing in health care - a literature review.

PubMed

Orwat, Carsten; Graefe, Andreas; Faulwasser, Timm

2008-06-19

The evolving concepts of pervasive computing, ubiquitous computing and ambient intelligence are increasingly influencing health care and medicine. Summarizing published research, this literature review provides an overview of recent developments and implementations of pervasive computing systems in health care. It also highlights some of the experiences reported in deployment processes. There is no clear definition of pervasive computing in the current literature. Thus specific inclusion criteria for selecting articles about relevant systems were developed. Searches were conducted in four scientific databases alongside manual journal searches for the period of 2002 to 2006. Articles included present prototypes, case studies and pilot studies, clinical trials and systems that are already in routine use. The searches identified 69 articles describing 67 different systems. In a quantitative analysis, these systems were categorized into project status, health care settings, user groups, improvement aims, and systems features (i.e., component types, data gathering, data transmission, systems functions). The focus is on the types of systems implemented, their frequency of occurrence and their characteristics. Qualitative analyses were performed of deployment issues, such as organizational and personnel issues, privacy and security issues, and financial issues. This paper provides a comprehensive access to the literature of the emerging field by addressing specific topics of application settings, systems features, and deployment experiences. Both an overview and an analysis of the literature on a broad and heterogeneous range of systems are provided. Most systems are described in their prototype stages. Deployment issues, such as implications on organization or personnel, privacy concerns, or financial issues are mentioned rarely, though their solution is regarded as decisive in transferring promising systems to a stage of regular operation. There is a need for further research on the deployment of pervasive computing systems, including clinical studies, economic and social analyses, user studies, etc.

Differential Entropy Preserves Variational Information of Near-Infrared Spectroscopy Time Series Associated With Working Memory

PubMed Central

Keshmiri, Soheil; Sumioka, Hidenubo; Yamazaki, Ryuji; Ishiguro, Hiroshi

2018-01-01

Neuroscience research shows a growing interest in the application of Near-Infrared Spectroscopy (NIRS) in analysis and decoding of the brain activity of human subjects. Given the correlation that is observed between the Blood Oxygen Dependent Level (BOLD) responses that are exhibited by the time series data of functional Magnetic Resonance Imaging (fMRI) and the hemoglobin oxy/deoxy-genation that is captured by NIRS, linear models play a central role in these applications. This, in turn, results in adaptation of the feature extraction strategies that are well-suited for discretization of data that exhibit a high degree of linearity, namely, slope and the mean as well as their combination, to summarize the informational contents of the NIRS time series. In this article, we demonstrate that these features are inefficient in capturing the variational information of NIRS data, limiting the reliability and the adequacy of the conclusion on their results. Alternatively, we propose the linear estimate of differential entropy of these time series as a natural representation of such information. We provide evidence for our claim through comparative analysis of the application of these features on NIRS data pertinent to several working memory tasks as well as naturalistic conversational stimuli. PMID:29922144

Electrospun Fibers for Recruitment and Differentiation of Stem Cells in Regenerative Medicine.

PubMed

Sankar, Sharanya; Sharma, Chandra S; Rath, Subha N; Ramakrishna, Seeram

2017-12-01

Electrospinning is a popular technique used to mimic the natural sub-micron features of the native tissue. The ultra-fine fibers provide a favorable extracellular matrix-like environment for regulation of cellular functions. This article summarizes and reviews the current advances in electrospun fiber application and focuses on the novel strategies applied for tissue regeneration and repair. It explores the different factors affecting the attachment and proliferation of mesenchymal stem cells (MSCs) on the electrospun substrates. The influence of different features of electrospun fibers in the differentiation of MSCs into specific lineages (bone, cartilage, tendon/ligament, and nerves) has been elaborated. In addition, the different techniques to mimic the hierarchical features of tissues and its effect on cellular functions are reviewed. Additionally, the new developments like three-dimensional (3D) electrospinning, 3D spheroid double strategy and the comparative analysis of dynamic and static culture on electrospun scaffolds are discussed. With the intricate understanding of the interaction between the cells and the electrospun fiber matrix we can aim to combine the newer strategies to overcome the existing challenges and improve the potential application of electrospun fibers in the field of tissue regeneration and repair. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Strategies for Teaching Children with Autism in Physical Education

ERIC Educational Resources Information Center

Groft-Jones, Melissa; Block, Martin E.

2006-01-01

The purpose of this article is to summarize information presented in the prior articles into practical strategies physical educators can use when teaching children with autism. The authors divided the article into three areas: (1) structuring the environment; (2) accommodating communication challenges; and (3) preventing challenging behaviors.…

From Cognitive-Domain Theory to Assessment Practice

ERIC Educational Resources Information Center

Bennett, Randy E.; Deane, Paul; van Rijn, Peter W.

2016-01-01

This article exemplifies how assessment design might be grounded in theory, thereby helping to strengthen validity claims. Spanning work across multiple related projects, the article first briefly summarizes an assessment system model for the elementary and secondary levels. Next the article describes how cognitive-domain theory and principles are…

A Resource on Behavioral Terminology: An Annotated Bibliography of "On Terms" Articles in "The Behavior Analyst"

ERIC Educational Resources Information Center

Carr, James E.; Briggs, Adam M.

2011-01-01

An annotated bibliography that summarizes the "On Terms" articles on behavior-analytic terminology from "The Behavior Analyst" is provided. Thirty-five articles published between 1979 and 2010 were identified, annotated, and classified using common behavior analysis course content frameworks. (Contains 1 table.)

[Trigemino-autonomic headache syndromes].

PubMed

Busch, V; May, A

2003-01-01

This review describes the characteristics of some rare severe primary headache syndromes without any structural lesions, which are summarized as the trigemino-autonomic headaches. Pain in these syndromes is associated with autonomic symptoms such as conjunctival injection, lacrimation, rhinorrhoe, ptosis or eyelid edema. This article summarizes the diagnostics, epidemiology and therapy of these conditions.

Automated video feature extraction : workshop summary report October 10-11 2012.

DOT National Transportation Integrated Search

2012-12-01

This report summarizes a 2-day workshop on automated video feature extraction. Discussion focused on the Naturalistic Driving : Study, funded by the second Strategic Highway Research Program, and also involved the companion roadway inventory dataset....

Major achievements of evidence-based traditional Chinese medicine in treating major diseases.

PubMed

Chao, Jung; Dai, Yuntao; Verpoorte, Robert; Lam, Wing; Cheng, Yung-Chi; Pao, Li-Heng; Zhang, Wei; Chen, Shilin

2017-09-01

A long history of use and extensive documentation of the clinical practices of traditional Chinese medicine resulted in a considerable number of classical preparations, which are still widely used. This heritage of our ancestors provides a unique resource for drug discovery. Already, a number of important drugs have been developed from traditional medicines, which in fact form the core of Western pharmacotherapy. Therefore, this article discusses the differences in drug development between traditional medicine and Western medicine. Moreover, the article uses the discovery of artemisinin as an example that illustrates the "bedside-bench-bedside" approach to drug discovery to explain that the middle way for drug development is to take advantage of the best features of these two distinct systems and compensate for certain weaknesses in each. This article also summarizes evidence-based traditional medicines and discusses quality control and quality assessment, the crucial steps in botanical drug development. Herbgenomics may provide effective tools to clarify the molecular mechanism of traditional medicines in the botanical drug development. The totality-of-the-evidence approach used by the U.S. Food and Drug Administration for botanical products provides the directions on how to perform quality control from the field throughout the entire production process. Copyright © 2017 Elsevier Inc. All rights reserved.

Catatonia in the medically ill: Etiology, diagnosis, and treatment. The Academy of Consultation-Liaison Psychiatry Evidence-Based Medicine Subcommittee Monograph.

PubMed

Denysenko, Lex; Sica, Nicole; Penders, Thomas M; Philbrick, Kemuel L; Walker, Audrey; Shaffer, Scott; Zimbrean, Paula; Freudenreich, Oliver; Rex, Nicole; Carroll, Brendan T; Francis, Andrew

2018-05-01

Catatonia in medically ill patients is rare but often unrecognized. This monograph summarizes current knowledge on the diagnosis, epidemiology, etiology, and management of catatonia occurring in the medical setting. PubMed searches were used to identify relevant articles from 1962 to present. More than 3,000 articles were obtained and reviewed for relevance, including references of articles identified by the initial search. Several areas were identified as important, including: (1) catatonia and delirium; (2) malignant catatonia; (3) pediatric catatonia; (4) catatonia associated with another medical condition (CAMC); (5) drug exposure and withdrawal syndromes associated with catatonia; and (6) treatment of catatonia in the medical setting. Catatonia in the medically ill appears to have numerous etiologies, although etiology does not seem to modify the general treatment approach of prompt administration of lorazepam. Delirium and catatonia are commonly comorbid in the medical setting and should not be viewed as mutually exclusive. Electroconvulsive therapy should be offered to patients who do not respond to benzodiazepines or have malignant features. Removing offending agents and treating the underlying medical condition is paramount when treating CAMC. Memantine or amantadine may be helpful adjunctive agents. There is not enough evidence to support the use of antipsychotics or stimulants in treating CAMC.

2000 Digital Avionics Highlights

NASA Technical Reports Server (NTRS)

Polites, Michael E.

2000-01-01

This article summarizes the highlights of recent events and developments in digital avionics in commercial aviation, military systems, and space. This article is about 1,200 words long. Information for the article was collected from other NASA centers, DoD, and industry. All information was previously cleared by the originating organizations. Information for the article was also gathered from Aviation Week and Space Technology and similar sources.

Synthesis of Research Symposium at CLD's 33rd International Conference on Learning Disabilities: "Must Reads for 2011"

ERIC Educational Resources Information Center

Weiser, Beverly L.; Reed, Deborah K.; Kethley, Caroline I.; Mathes, Patricia G.

2012-01-01

In October 2011, Council for Learning Disabilities' (CLD's) research committee members (i.e., authors of this article) presented their "Must Reads" at the organization's 33rd Annual International Conference on Learning Disabilities. In this article, the presenters summarize a few of their selected articles and state why each article is a "Must…

Feature Articles on African Americans in Sports Illustrated in the 1990s

ERIC Educational Resources Information Center

Angela Lumpkin

2009-01-01

This descriptive study examined whether the coverage of African Americans in the feature articles in Sports Illustrated during the 1990s was representative of their participation levels. Nearly half of the articles featured European Americans; about one-third featured African Americans. More African Americans were featured in basketball, boxing,…

The Pedagogical Triangle or Think 3's.

ERIC Educational Resources Information Center

McDonnell, Thomas E.

1979-01-01

This article is a semi-satire of suggestions for teachers on how to improve their classroom instructional strategies and curriculum. Many aspects of education and teaching occur in multiples of three and this article summarizes this phenomenon. (Author)

Symposium on Integrating the Science of Environmental Justice into Decision-Making at the Environmental Protection Agency: An Overview

PubMed Central

Payne-Sturges, Devon; Garcia, Lisa; Lee, Charles; Zenick, Hal; Grevatt, Peter; Sanders, William H.; Case, Heather; Dankwa-Mullan, Irene

2011-01-01

In March 2010, the Environmental Protection Agency (EPA) collaborated with government and nongovernmental organizations to host a groundbreaking symposium, “Strengthening Environmental Justice Research and Decision Making: A Symposium on the Science of Disproportionate Environmental Health Impacts.” The symposium provided a forum for discourse on the state of scientific knowledge about factors identified by EPA that may contribute to higher burdens of environmental exposure or risk in racial/ethnic minorities and low-income populations. Also featured were discussions on how environmental justice considerations may be integrated into EPA's analytical and decision-making frameworks and on research needs for advancing the integration of environmental justice into environmental policymaking. We summarize key discussions and conclusions from the symposium and briefly introduce the articles in this issue. PMID:22028456

Transfer printing techniques for materials assembly and micro/nanodevice fabrication.

PubMed

Carlson, Andrew; Bowen, Audrey M; Huang, Yonggang; Nuzzo, Ralph G; Rogers, John A

2012-10-09

Transfer printing represents a set of techniques for deterministic assembly of micro-and nanomaterials into spatially organized, functional arrangements with two and three-dimensional layouts. Such processes provide versatile routes not only to test structures and vehicles for scientific studies but also to high-performance, heterogeneously integrated functional systems, including those in flexible electronics, three-dimensional and/or curvilinear optoelectronics, and bio-integrated sensing and therapeutic devices. This article summarizes recent advances in a variety of transfer printing techniques, ranging from the mechanics and materials aspects that govern their operation to engineering features of their use in systems with varying levels of complexity. A concluding section presents perspectives on opportunities for basic and applied research, and on emerging use of these methods in high throughput, industrial-scale manufacturing. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

[Zoonotic diseases caused by bacteria of the genus Bartonella genus: new reservoirs ? New vectors?].

PubMed

Chomel, Bruno B; Boulouis, Henri-Jean

2005-03-01

Domestic animals and wildlife represent a large reservoir for bartonellae, at least eight species or subspecies of which have been reported to cause zoonotic infections. In addition, numerous orphan clinical syndromes are now being attributed to Bartonella henselae infection. Many mammalian species, including cats, dogs, rodents and ruminants are the main bartonellae reservoirs. Cats are the main reservoir for B. henselae. It appears that domestic dogs, at least in non tropical regions, are more likely to be accidental hosts than reservoirs, and constitute excellent sentinels for human infections. Bartonellae are vector-borne bacteria. The mode of B. henselae transmission by cat fleas is now better understood, but new potential vectors have recently been identified, including ticks and biting flies. This articles summarizes current knowledge of the etiology, new clinical features and epidemiological characteristics of these emerging zoonoses.

Toxoplasma gondii infection in humans in China

PubMed Central

2011-01-01

Toxoplasmosis is a zoonotic infection of humans and animals, caused by the opportunistic protozoan Toxoplasma gondii, a parasite belonging to the phylum Apicomplexa. Infection in pregnant women may lead to abortion, stillbirth or other serious consequences in newborns. Infection in immunocompromised patients can be fatal if not treated. On average, one third of people are chronically infected worldwide. Although very limited information from China has been published in the English journals, T. gondii infection is actually a significant human health problem in China. In the present article, we reviewed the clinical features, transmission, prevalence of T. gondii infection in humans in China, and summarized genetic characterizations of reported T. gondii isolates. Educating the public about the risks associated with unhealthy food and life style habits, tracking serological examinations to special populations, and measures to strengthen food and occupational safety are discussed. PMID:21864327

Predicting remaining life by fusing the physics of failure modeling with diagnostics

NASA Astrophysics Data System (ADS)

Kacprzynski, G. J.; Sarlashkar, A.; Roemer, M. J.; Hess, A.; Hardman, B.

2004-03-01

Technology that enables failure prediction of critical machine components (prognostics) has the potential to significantly reduce maintenance costs and increase availability and safety. This article summarizes a research effort funded through the U.S. Defense Advanced Research Projects Agency and Naval Air System Command aimed at enhancing prognostic accuracy through more advanced physics-of-failure modeling and intelligent utilization of relevant diagnostic information. H-60 helicopter gear is used as a case study to introduce both stochastic sub-zone crack initiation and three-dimensional fracture mechanics lifing models along with adaptive model updating techniques for tuning key failure mode variables at a local material/damage site based on fused vibration features. The overall prognostic scheme is aimed at minimizing inherent modeling and operational uncertainties via sensed system measurements that evolve as damage progresses.

Tubal telocytes: factor infertility reason?

PubMed

Aleksandrovych, Veronika; Sajewicz, Marek; Walocha, Jerzy A; Gil, Krzysztof

Infertility is actually widespread pathological condition, which affected one in every four couples in developing countries. Approximately one third of all cases are connected with tubal factor infertility, o en accompanies by endometriosis, acute salpingitis, urogenital infections etc. The newly identified telocytes (TCs) have multiple potential bio-functions and might participate in the fertility problems. They influence on structural and functional integrity of oviduct tissue. Despite recent discovery, TCs involvement in the majority of physiological and pathological processes is still unclear and require significant increasing of deep observations and data analysis. Focusing on female reproductive system help better understands the main reasons of infertility, while evaluation of TCs impact on Fallopian tube and uterus contractility might be a key point of its correction. The article summarizes the main features of telocytes in Fallopian tubes, emphasizing their involvement in pathophysiological processes and tubal factor infertility.

Membrane Fusion Involved in Neurotransmission: Glimpse from Electron Microscope and Molecular Simulation

PubMed Central

Yang, Zhiwei; Gou, Lu; Chen, Shuyu; Li, Na; Zhang, Shengli; Zhang, Lei

2017-01-01

Membrane fusion is one of the most fundamental physiological processes in eukaryotes for triggering the fusion of lipid and content, as well as the neurotransmission. However, the architecture features of neurotransmitter release machinery and interdependent mechanism of synaptic membrane fusion have not been extensively studied. This review article expounds the neuronal membrane fusion processes, discusses the fundamental steps in all fusion reactions (membrane aggregation, membrane association, lipid rearrangement and lipid and content mixing) and the probable mechanism coupling to the delivery of neurotransmitters. Subsequently, this work summarizes the research on the fusion process in synaptic transmission, using electron microscopy (EM) and molecular simulation approaches. Finally, we propose the future outlook for more exciting applications of membrane fusion involved in synaptic transmission, with the aid of stochastic optical reconstruction microscopy (STORM), cryo-EM (cryo-EM), and molecular simulations. PMID:28638320

Synthesis of Hollow Sphere and 1D Structural Materials by Sol-Gel Process.

PubMed

Li, Fa-Liang; Zhang, Hai-Jun

2017-08-25

The sol-gel method is a simple and facile wet chemical process for fabricating advanced materials with high homogeneity, high purity, and excellent chemical reactivity at a relatively low temperature. By adjusting the processing parameters, the sol-gel technique can be used to prepare hollow sphere and 1D structural materials that exhibit a wide application in the fields of catalyst, drug or gene carriers, photoactive, sensors and Li-ion batteries. This feature article reviewed the development of the preparation of hollow sphere and 1D structural materials using the sol-gel method. The effects of calcination temperature, soaking time, pH value, surfactant, etc., on the preparation of hollow sphere and 1D structural materials were summarized, and their formation mechanisms were generalized. Finally, possible future research directions of the sol-gel technique were outlined.

Synthesis of Hollow Sphere and 1D Structural Materials by Sol-Gel Process

PubMed Central

Li, Fa-Liang; Zhang, Hai-Jun

2017-01-01

The sol-gel method is a simple and facile wet chemical process for fabricating advanced materials with high homogeneity, high purity, and excellent chemical reactivity at a relatively low temperature. By adjusting the processing parameters, the sol-gel technique can be used to prepare hollow sphere and 1D structural materials that exhibit a wide application in the fields of catalyst, drug or gene carriers, photoactive, sensors and Li-ion batteries. This feature article reviewed the development of the preparation of hollow sphere and 1D structural materials using the sol-gel method. The effects of calcination temperature, soaking time, pH value, surfactant, etc., on the preparation of hollow sphere and 1D structural materials were summarized, and their formation mechanisms were generalized. Finally, possible future research directions of the sol-gel technique were outlined. PMID:28841188

Targeting blood–brain barrier changes during inflammatory pain: an opportunity for optimizing CNS drug delivery

PubMed Central

Ronaldson, Patrick T; Davis, Thomas P

2012-01-01

The blood–brain barrier (BBB) is the most significant obstacle to effective CNS drug delivery. It possesses structural and biochemical features (i.e., tight-junction protein complexes and, influx and efflux transporters) that restrict xenobiotic permeation. Pathophysiological stressors (i.e., peripheral inflammatory pain) can alter BBB tight junctions and transporters, which leads to drug-permeation changes. This is especially critical for opioids, which require precise CNS concentrations to be safe and effective analgesics. Recent studies have identified molecular targets (i.e., endogenous transporters and intracellular signaling systems) that can be exploited for optimization of CNS drug delivery. This article summarizes current knowledge in this area and emphasizes those targets that present the greatest opportunity for controlling drug permeation and/or drug transport across the BBB in an effort to achieve optimal CNS opioid delivery. PMID:22468221

Microfluidics for genome-wide studies involving next generation sequencing

PubMed Central

Murphy, Travis W.; Lu, Chang

2017-01-01

Next-generation sequencing (NGS) has revolutionized how molecular biology studies are conducted. Its decreasing cost and increasing throughput permit profiling of genomic, transcriptomic, and epigenomic features for a wide range of applications. Microfluidics has been proven to be highly complementary to NGS technology with its unique capabilities for handling small volumes of samples and providing platforms for automation, integration, and multiplexing. In this article, we review recent progress on applying microfluidics to facilitate genome-wide studies. We emphasize on several technical aspects of NGS and how they benefit from coupling with microfluidic technology. We also summarize recent efforts on developing microfluidic technology for genomic, transcriptomic, and epigenomic studies, with emphasis on single cell analysis. We envision rapid growth in these directions, driven by the needs for testing scarce primary cell samples from patients in the context of precision medicine. PMID:28396707

MR imaging of the elbow in the injured athlete.

PubMed

Wenzke, Daniel R

2013-03-01

This article summarizes key MR imaging findings in common athletic elbow injuries including little leaguer's elbow, Panner disease, osteochondritis dissecans, olecranon stress fracture, occult fracture, degenerative osteophyte formation, flexor-pronator strain, ulnar collateral ligament tear, lateral ulnar collateral ligament and radial collateral ligament tear, lateral epicondylitis, medial epicondylitis, biceps tear, bicipitoradial bursitis, triceps tear, olecranon bursitis, ulnar neuropathy, posterior interosseous nerve syndrome, and radial tunnel syndrome. The article also summarizes important technical considerations in elbow MR imaging that enhance image quality and contribute to the radiologist's success. Copyright © 2013 Elsevier Inc. All rights reserved.

MeSH indexing based on automatically generated summaries

PubMed Central

2013-01-01

Background MEDLINE citations are manually indexed at the U.S. National Library of Medicine (NLM) using as reference the Medical Subject Headings (MeSH) controlled vocabulary. For this task, the human indexers read the full text of the article. Due to the growth of MEDLINE, the NLM Indexing Initiative explores indexing methodologies that can support the task of the indexers. Medical Text Indexer (MTI) is a tool developed by the NLM Indexing Initiative to provide MeSH indexing recommendations to indexers. Currently, the input to MTI is MEDLINE citations, title and abstract only. Previous work has shown that using full text as input to MTI increases recall, but decreases precision sharply. We propose using summaries generated automatically from the full text for the input to MTI to use in the task of suggesting MeSH headings to indexers. Summaries distill the most salient information from the full text, which might increase the coverage of automatic indexing approaches based on MEDLINE. We hypothesize that if the results were good enough, manual indexers could possibly use automatic summaries instead of the full texts, along with the recommendations of MTI, to speed up the process while maintaining high quality of indexing results. Results We have generated summaries of different lengths using two different summarizers, and evaluated the MTI indexing on the summaries using different algorithms: MTI, individual MTI components, and machine learning. The results are compared to those of full text articles and MEDLINE citations. Our results show that automatically generated summaries achieve similar recall but higher precision compared to full text articles. Compared to MEDLINE citations, summaries achieve higher recall but lower precision. Conclusions Our results show that automatic summaries produce better indexing than full text articles. Summaries produce similar recall to full text but much better precision, which seems to indicate that automatic summaries can efficiently capture the most important contents within the original articles. The combination of MEDLINE citations and automatically generated summaries could improve the recommendations suggested by MTI. On the other hand, indexing performance might be dependent on the MeSH heading being indexed. Summarization techniques could thus be considered as a feature selection algorithm that might have to be tuned individually for each MeSH heading. PMID:23802936

The Best of CAUSE/EFFECT: 1978-1991.

ERIC Educational Resources Information Center

Rudy, Julia A., Ed.

This issue of the higher education information technology magazine, CAUSE/EFFECT, presents in six articles six summaries of the best from this journal since 1978. The articles each summarize the writing done over the years in one of six key areas. The articles are as follows: (1) "Rise of Infrastructure" by Kenneth J. Klingenstein and…

An Annotated Bibliography of Verbal Behavior Articles Published outside of "The Analysis of Verbal Behavior: 2016"

ERIC Educational Resources Information Center

Lechago, Sarah A.; Jackson, Rachel E.; Oda, Fernanda S.

2017-01-01

An annotated bibliography is provided that summarizes journal articles on verbal behavior published outside of "The Analysis of Verbal Behavior" in 2016, the primary journal for scholarship in this area. Thirty-seven such articles were identified and annotated as a resource for practitioners, researchers, and educators.

Facilitating Peer Discourse to Support Third Graders' Comprehension of the News

ERIC Educational Resources Information Center

Jordan, Michelle; Massad, Michael, Sr.

2014-01-01

This study explored how one third-grade teacher facilitated daily peer-led discussions around articles from a local newspaper. Two students were assigned to select and summarize an article, then lead a whole-class discussion with the teacher's help. The teacher differentially scaffolded engagement with newspaper articles, adaptively responding to…

The Recognition of Effective Teaching in Latin America: Awards to Excellence

ERIC Educational Resources Information Center

Vaillant, Denise; Rossel, Cecilia

2012-01-01

The main goal of this article is to review recent experience of effective teaching recognition policies in Latin America. The article examines the main issues related to the recognition of teaching by summarizing experiences of awards to teachers in the region, describing their results and limitations. The article outlines the most important…

Art as Social Concern

ERIC Educational Resources Information Center

Hodge, Stephanie

2010-01-01

In this article, the author describes how her eleventh- and twelfth-grade portfolio class used art as a social concern through a sketchbook and a linoleum print. Students thumbed through copies of the "New York Times" to find an article that described a modern-day social concern. Students were assigned to choose an article, summarize it, and come…

An Annotated Bibliography of Verbal Behavior Articles Published outside of "The Analysis of Verbal Behavior": 2015

ERIC Educational Resources Information Center

Lechago, Sarah A.; Phillips, Lauren A.

2016-01-01

An annotated bibliography is provided that summarizes journal articles on verbal behavior published outside of "The Analysis of Verbal Behavior" in 2015, the primary journal for scholarship in this area. Thirty such articles were identified and annotated as a resource for practitioners, researchers, and educators.

LGBTQ Research in Higher Education: A Review of Journal Articles, 2000-2003

ERIC Educational Resources Information Center

Dilley, Patrick

2004-01-01

A review of electronic databases identified 27 research-based articles concerning LGBTQ issues in higher education between 2000 and 2003. These articles are summarized into three categories: studies of campus climate, student life issues, and college teaching. Suggestions are provided for future research on postsecondary students; faculty;…

East Europe Report, Economic and Industrial Affairs, No. 2429

DTIC Science & Technology

1983-08-02

Draft Version of Controversial New Income Tax Law Summarized (T.J.; ZYCIE GOSPODARCZE, No 20, 15 May 83) 32 Utilization of Polish Specialists... INCOME TAX LAW SUMMARIZED Warsaw ZYCIE GOSPODARCZE in Polish No 20, 15 May 83 p 11 [Article by T.J.] [Text] The Ministry of Finance has prepared a

CFB repowering options

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gittinger, J.

1996-12-31

Circulating fluidized bed CFB repowering options are summarized. The following topics are discussed: why repower with CFB technology; advantages of repowering; two forms of of repowering; B and N`s internal recirculation CFB; space-saving design features; cost-saving design features; Ukrainian repowering project; and candidates for repowering.

Agricultural hydrology and water quality II: Introduction to the featured collection

USDA-ARS?s Scientific Manuscript database

Agricultural hydrology and water quality is a multidisciplinary field devoted to understanding the interrelationship between modern agriculture and water resources. This paper summarizes a featured collection of 10 manuscripts emanating from the 2013 American Water Resources Association Specialty Co...

Network science and the human brain: Using graph theory to understand the brain and one of its hubs, the amygdala, in health and disease.

PubMed

Mears, David; Pollard, Harvey B

2016-06-01

Over the past 15 years, the emerging field of network science has revealed the key features of brain networks, which include small-world topology, the presence of highly connected hubs, and hierarchical modularity. The value of network studies of the brain is underscored by the range of network alterations that have been identified in neurological and psychiatric disorders, including epilepsy, depression, Alzheimer's disease, schizophrenia, and many others. Here we briefly summarize the concepts of graph theory that are used to quantify network properties and describe common experimental approaches for analysis of brain networks of structural and functional connectivity. These range from tract tracing to functional magnetic resonance imaging, diffusion tensor imaging, electroencephalography, and magnetoencephalography. We then summarize the major findings from the application of graph theory to nervous systems ranging from Caenorhabditis elegans to more complex primate brains, including man. Focusing, then, on studies involving the amygdala, a brain region that has attracted intense interest as a center for emotional processing, fear, and motivation, we discuss the features of the amygdala in brain networks for fear conditioning and emotional perception. Finally, to highlight the utility of graph theory for studying dysfunction of the amygdala in mental illness, we review data with regard to changes in the hub properties of the amygdala in brain networks of patients with depression. We suggest that network studies of the human brain may serve to focus attention on regions and connections that act as principal drivers and controllers of brain function in health and disease. Published 2016. This article is a U.S. Government work and is in the public domain in the USA.

Progress on first-principles-based materials design for hydrogen storage.

PubMed

Park, Noejung; Choi, Keunsu; Hwang, Jeongwoon; Kim, Dong Wook; Kim, Dong Ok; Ihm, Jisoon

2012-12-04

This article briefly summarizes the research activities in the field of hydrogen storage in sorbent materials and reports our recent works and future directions for the design of such materials. Distinct features of sorption-based hydrogen storage methods are described compared with metal hydrides and complex chemical hydrides. We classify the studies of hydrogen sorbent materials in terms of two key technical issues: (i) constructing stable framework structures with high porosity, and (ii) increasing the binding affinity of hydrogen molecules to surfaces beyond the usual van der Waals interaction. The recent development of reticular chemistry is summarized as a means for addressing the first issue. Theoretical studies focus mainly on the second issue and can be grouped into three classes according to the underlying interaction mechanism: electrostatic interactions based on alkaline cations, Kubas interactions with open transition metals, and orbital interactions involving Ca and other nontransitional metals. Hierarchical computational methods to enable the theoretical predictions are explained, from ab initio studies to molecular dynamics simulations using force field parameters. We also discuss the actual delivery amount of stored hydrogen, which depends on the charging and discharging conditions. The usefulness and practical significance of the hydrogen spillover mechanism in increasing the storage capacity are presented as well.

[Fundación Mundo Bipolar: learning among peers in the service of recovery].

PubMed

Morales Cano, Guadalupe

2013-01-01

Due to severe mental illness, such as a diagnosis of bipolar disorder, people's quality of life may be seriously compromised and they may bear the risk of losing opportunities and being socially isolated as a result of stigma and discrimination. Early diagnosis is crucial, as a recovery process is possible with appropriate medical and psychosocial treatment. A person affected by such circumstances, with adequate training, can learn to handle his condition by himself and become expert by experience. This article depicts how learning among peers, based to a large degree on empathy, enables and promotes self management and, at the same time, a larger political and social consciousness. This has been affirmed by the virtual community of bipolarweb since 2002 and, subsequently, as a further development by the Fundación Mundo Bipolar. This foundation, which offers a training program for people affected by bipolar disorder, engages in several activities and goals which are described in this paper. It also has developed a multidisciplinary program for the training of trainers. Some features of these programs are summarized, with a special emphasis on the fact that trained students are encouraged to give lectures for high school students. This paper summarizes qualitative evaluations made by participants that have followed each of the sessions of the training programs.

Progress on first-principles-based materials design for hydrogen storage

PubMed Central

Park, Noejung; Choi, Keunsu; Hwang, Jeongwoon; Kim, Dong Wook; Kim, Dong Ok; Ihm, Jisoon

2012-01-01

This article briefly summarizes the research activities in the field of hydrogen storage in sorbent materials and reports our recent works and future directions for the design of such materials. Distinct features of sorption-based hydrogen storage methods are described compared with metal hydrides and complex chemical hydrides. We classify the studies of hydrogen sorbent materials in terms of two key technical issues: (i) constructing stable framework structures with high porosity, and (ii) increasing the binding affinity of hydrogen molecules to surfaces beyond the usual van der Waals interaction. The recent development of reticular chemistry is summarized as a means for addressing the first issue. Theoretical studies focus mainly on the second issue and can be grouped into three classes according to the underlying interaction mechanism: electrostatic interactions based on alkaline cations, Kubas interactions with open transition metals, and orbital interactions involving Ca and other nontransitional metals. Hierarchical computational methods to enable the theoretical predictions are explained, from ab initio studies to molecular dynamics simulations using force field parameters. We also discuss the actual delivery amount of stored hydrogen, which depends on the charging and discharging conditions. The usefulness and practical significance of the hydrogen spillover mechanism in increasing the storage capacity are presented as well. PMID:23161910

A Review on Breathing Behaviors of Metal-Organic-Frameworks (MOFs) for Gas Adsorption

PubMed Central

Alhamami, Mays; Doan, Huu; Cheng, Chil-Hung

2014-01-01

Metal-organic frameworks (MOFs) are a new class of microporous materials that possess framework flexibility, large surface areas, “tailor-made” framework functionalities, and tunable pore sizes. These features empower MOFs superior performances and broader application spectra than those of zeolites and phosphine-based molecular sieves. In parallel with designing new structures and new chemistry of MOFs, the observation of unique breathing behaviors upon adsorption of gases or solvents stimulates their potential applications as host materials in gas storage for renewable energy. This has attracted intense research energy to understand the causes at the atomic level, using in situ X-ray diffraction, calorimetry, Fourier transform infrared spectroscopy, and molecular dynamics simulations. This article is developed in the following order: first to introduce the definition of MOFs and the observation of their framework flexibility. Second, synthesis routes of MOFs are summarized with the emphasis on the hydrothermal synthesis, owing to the environmental-benign and economically availability of water. Third, MOFs exhibiting breathing behaviors are summarized, followed by rationales from thermodynamic viewpoint. Subsequently, effects of various functionalities on breathing behaviors are appraised, including using post-synthetic modification routes. Finally, possible framework spatial requirements of MOFs for yielding breathing behaviors are highlighted as the design strategies for new syntheses. PMID:28788614

[A review of thirty years of activity of the Research Program in Psychiatric Epidemiology (PEPSI) of the CONICET].

PubMed

Pavlovsky, Federico

2003-01-01

This article summarizes the activity of the Programa de Investigaciones en Epidemiología Psiquiátrica (PEPSI) (Research Program in Psychiatric Epidemiology) of the CONICET, directed for more than thirty years by Fernando Pages Larraya. After an anthropologic psychiatric experience done in the Gran Chaco Gualamba, by the end of the 60s, Pages Larraya and his team developed the theory of Cultural Isoidias, zones into which the country could be divided for epidemiologic studies. This article summarizes some of the principal lines of investigation of this program which departures from an initial study of the prevalence of mental diseases in Argentina. Other lines of research (such as a study about marginality, about Alzheimer's disease, about alcoholism and about AIDS) are summarized very briefly so as to give the reader an idea about the enormous field of study embraced by the PEPSI.

Automatic Text Summarization for Indonesian Language Using TextTeaser

NASA Astrophysics Data System (ADS)

Gunawan, D.; Pasaribu, A.; Rahmat, R. F.; Budiarto, R.

2017-04-01

Text summarization is one of the solution for information overload. Reducing text without losing the meaning not only can save time to read, but also maintain the reader’s understanding. One of many algorithms to summarize text is TextTeaser. Originally, this algorithm is intended to be used for text in English. However, due to TextTeaser algorithm does not consider the meaning of the text, we implement this algorithm for text in Indonesian language. This algorithm calculates four elements, such as title feature, sentence length, sentence position and keyword frequency. We utilize TextRank, an unsupervised and language independent text summarization algorithm, to evaluate the summarized text yielded by TextTeaser. The result shows that the TextTeaser algorithm needs more improvement to obtain better accuracy.

Significant publications on infectious diseases pharmacotherapy in 2014.

PubMed

Phe, Kady; Cadle, Richard M; Guervil, David J; Guzman, Oscar E; Lockwood, Ashley M; Perez, Katherine K; Vuong, Nancy N; Aitken, Samuel L

2015-08-15

The most important articles on infectious diseases (ID) pharmacotherapy published in the peer-reviewed literature in 2014, as nominated and selected by panels of pharmacists and others with ID expertise, are summarized. Members of the Houston Infectious Diseases Network were asked to nominate articles published in 2014 from prominent peer-reviewed journals that were felt to have a major impact in the field of ID pharmacotherapy. A list of 19 nominated articles on general ID-related topics and 9 articles specifically related to human immunodeficiency virus (HIV) infection or acquired immunodeficiency syndrome (AIDS) was compiled. In a national online survey, members of the Society of Infectious Diseases Pharmacists (SIDP) were asked to select from the list 10 general ID articles believed to have made a significant contribution to the field of ID pharmacotherapy and 1 article contributing to HIV/AIDS pharmacotherapy. Of the 291 SIDP members surveyed, 134 (46%) and 56 (19%) participated in the selection of general ID-related articles and HIV/AIDS-related articles, respectively. The 11 highest-ranked papers (10 general ID-related articles, 1 HIV/AIDS-related article) are summarized here. With the vast number of articles published each year, it is difficult to remain up-to-date on current, significant ID pharmacotherapy publications. This review of significant publications in 2014 may be helpful by lessening this burden. Copyright © 2015 by the American Society of Health-System Pharmacists, Inc. All rights reserved.

Solvent Recycling for Shipyards

DTIC Science & Technology

1993-05-01

Suvey results are included in Section 5) Survey manufacturers and compile information on available equipment and features . (Data is summarized in Section...should be placed on safety features . Important safety features include explosion-proof electricals and grounding protection, overpressure relief valves...solvent can dissolve a polymer plastic liner, or extract water from a clay liner, resulting in liner leakage. The threat is compounded by the ability

Nuclear Reactor Safety--The APS Submits its Report

ERIC Educational Resources Information Center

Physics Today, 1975

1975-01-01

Presents the summary section of the American Physical Society (APS) report on the safety features of the light-water reactor, reviews the design, construction, and operation of a reactor and outlines the primary engineered safety features. Summarizes the major recommendations of the study group. (GS)

Hospital finance.

PubMed

Herman, M J

1998-01-01

This article summarizes key areas of focus for the analysis of risk in the hospital segment of the health care industry. The article is written from a commercial bank lending perspective. Both for-profit (C-corporations) and 501 (c)(3) not-for-profit segments are addressed.

Introduction to the Special Series on Participatory Action Research.

ERIC Educational Resources Information Center

Park, Hyun-Sook; Meyer, Luanna; Goetz, Lori

1998-01-01

This introductory article discusses the benefits of participatory action research (PAR), including the empowerment of participants in research and the research process, the difficulties PAR presents, and summarizes following articles in a special series on the facets of PAR. (CR)

Ethics and Scientific Publication

ERIC Educational Resources Information Center

Benos, Dale J.; Fabres, Jorge; Farmer, John; Gutierrez, Jessica P.; Hennessy, Kristin; Kosek, David; Lee, Joo Hyoung; Olteanu, Dragos; Russell, Tara; Wang, Kai

2005-01-01

This article summarizes the major categories of ethical violations encountered during submission, review, and publication of scientific articles. We discuss data fabrication and falsification, plagiarism, redundant and duplicate publication, conflict of interest, authorship, animal and human welfare, and reviewer responsibility. In each section,…

Crisis Management

ERIC Educational Resources Information Center

Brock, Stephen E., Ed.

2011-01-01

This paper presents summaries of four articles relevant to school crisis response. The first article, "Peritraumatic Dissociation Predicts Posttraumatic Stress in Youth Following Accidents" summarized by Jim Matthews, suggests that peritraumatic dissociation is a powerful predictor of PTSD symptoms among youth who have been in a car…

A Content and Methodological Review of Articles Concerning Multiracial Issues in Six Major Counseling Journals

ERIC Educational Resources Information Center

Edwards, Lisa M.; Pedrotti, Jennifer Teramoto

2008-01-01

This study describes a comprehensive content and methodological review of articles about multiracial issues in 6 journals related to counseling up to the year 2006. The authors summarize findings about the 18 articles that emerged from this review of the "Journal of Counseling Psychology," "Journal of Counseling & Development," "The Counseling…

Psoriasis, psoriatic arthritis, and rheumatoid arthritis: Is all inflammation the same?

PubMed

Coates, Laura C; FitzGerald, Oliver; Helliwell, Philip S; Paul, Carle

2016-12-01

To review the pathophysiology, co-morbidities, and therapeutic options for psoriasis, psoriatic arthritis and rheumatoid arthritis in order to further understand the similarities and differences in treatment paradigms in the management of each disease. New targets for individualized therapeutic decisions are also identified with the aim of improving therapeutic outcome and reducing toxicity. Using the PubMed database, we searched literature published from 2000 to 2015 using combinations of the key words "psoriasis," "psoriatic arthritis," "rheumatoid arthritis," "pathogenesis," "immunomodulation," and "treatment." This was a non-systematic review and there were no formal inclusion and exclusion criteria. Abstracts identified in the search were screened for relevance and articles considered appropriate evaluated further. References within these selected articles were also screened. Information was extracted from 198 articles for inclusion in this report. There was no formal data synthesis. Articles were reviewed and summarized according to disease area (psoriasis, psoriatic arthritis, and rheumatoid arthritis). The pathophysiology of psoriasis, psoriatic arthritis, and rheumatoid arthritis involves chronic inflammation mediated by pro-inflammatory cytokines. Dysfunction in integrated signaling pathways affecting different constituents of the immune system result in varying clinical features in the three diseases. Co-morbidities, including cardiovascular disease, malignancies, and non-alcoholic fatty liver disease are increased. Increased understanding of the immunopathogenesis allowed development of targeted treatments; however, despite a variety of potentially predictive genetic, protein and cellular biomarkers, there is still significant unmet need in these three inflammatory disorders. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

Research Summaries

ERIC Educational Resources Information Center

Brock, Stephen E., Ed.

2011-01-01

This article presents summaries of three articles relevant to school crisis response: (1) "Factors Contributing to Posttraumatic Growth," summarized by Steve DeBlois; (2) "Psychological Debriefing in Cross-Cultural Contexts" (Stacey Rice); and (3) "Brain Abnormalities in PTSD" (Sunny Windingstad). The first summary reports the findings of a…

Improving customer satisfaction: emerging lessons about strategy and implementation, Part 2.

PubMed

Morton, J

1995-01-01

This article describes a six-phase strategy designed to systematically improve customer satisfaction across an entire managed care system. Part 1 (Spring 1995) of this two-part series summarized the theoretical underpinnings of the approach and highlighted the first two phases of the improvement strategy. Those phases involve systematically listening to the organization's customers and using customer information to strategically target key areas for improvement. This article describes the specifics of the last four phases of the strategy; these phases involve achieving and sustaining unprecedented levels of improvement in targeted areas. Initial results and emerging lessons associated with the implementation of this strategy are summarized.

[Symptoms diagnosis and treatment of dyscalulia].

PubMed

Ise, Elena; Schulte-Körne, Gerd

2013-07-01

Children with dyscalculia show deficits in basic numerical processing which cause difficulties in the acquisition of mathematical skills. This article provides an overview of current research findings regarding the symptoms, cause, and prognosis of dyscalculia, and it summarizes recent developments in the diagnosis, early intervention, and treatment thereof. Diagnosis has improved recently because newly developed tests focus not only on the math curriculum, but also on basic skills found to be impaired in dyscalculia. A controversial debate continues with regard to IQ achievement discrepancy. International studies have demonstrated the effectiveness of specialized interventions. This article summarizes the research findings from intervention studies, describes different treatment approaches, and discusses implications for clinical practice.

Pemphigus and smoking- insights from a big data analysis.

PubMed

Kridin, Khalaf; Comaneshter, Doron; Batat, Erez; Cohen, Arnon D

2018-04-28

We have read with great interest the manuscript written by Lai et al.(1). The authors performed a systematic review and pooled-analysis aiming to summarize the current knowledge regarding the prevalence of smoking among patients with pemphigus relative to control subjects. By summarizing the findings of 13 observational studies comprising 3046 pemphigus patients, a pooled OR of 0.9 (95% CI, 0.82-0.99; P<0.05) was revealed indicating that smoking may exert a protective effect against the development of pemphigus(1). This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

Figure-associated text summarization and evaluation.

PubMed

Polepalli Ramesh, Balaji; Sethi, Ricky J; Yu, Hong

2015-01-01

Biomedical literature incorporates millions of figures, which are a rich and important knowledge resource for biomedical researchers. Scientists need access to the figures and the knowledge they represent in order to validate research findings and to generate new hypotheses. By themselves, these figures are nearly always incomprehensible to both humans and machines and their associated texts are therefore essential for full comprehension. The associated text of a figure, however, is scattered throughout its full-text article and contains redundant information content. In this paper, we report the continued development and evaluation of several figure summarization systems, the FigSum+ systems, that automatically identify associated texts, remove redundant information, and generate a text summary for every figure in an article. Using a set of 94 annotated figures selected from 19 different journals, we conducted an intrinsic evaluation of FigSum+. We evaluate the performance by precision, recall, F1, and ROUGE scores. The best FigSum+ system is based on an unsupervised method, achieving F1 score of 0.66 and ROUGE-1 score of 0.97. The annotated data is available at figshare.com (http://figshare.com/articles/Figure_Associated_Text_Summarization_and_Evaluation/858903).

Figure-Associated Text Summarization and Evaluation

PubMed Central

Polepalli Ramesh, Balaji; Sethi, Ricky J.; Yu, Hong

2015-01-01

Biomedical literature incorporates millions of figures, which are a rich and important knowledge resource for biomedical researchers. Scientists need access to the figures and the knowledge they represent in order to validate research findings and to generate new hypotheses. By themselves, these figures are nearly always incomprehensible to both humans and machines and their associated texts are therefore essential for full comprehension. The associated text of a figure, however, is scattered throughout its full-text article and contains redundant information content. In this paper, we report the continued development and evaluation of several figure summarization systems, the FigSum+ systems, that automatically identify associated texts, remove redundant information, and generate a text summary for every figure in an article. Using a set of 94 annotated figures selected from 19 different journals, we conducted an intrinsic evaluation of FigSum+. We evaluate the performance by precision, recall, F1, and ROUGE scores. The best FigSum+ system is based on an unsupervised method, achieving F1 score of 0.66 and ROUGE-1 score of 0.97. The annotated data is available at figshare.com (http://figshare.com/articles/Figure_Associated_Text_Summarization_and_Evaluation/858903). PMID:25643357

Features of a Mobile Support App for Patients With Chronic Obstructive Pulmonary Disease: Literature Review and Current Applications.

PubMed

Sobnath, Drishty D; Philip, Nada; Kayyali, Reem; Nabhani-Gebara, Shereen; Pierscionek, Barbara; Vaes, Anouk W; Spruit, Martijn A; Kaimakamis, Evangelos

2017-02-20

Chronic obstructive pulmonary disease (COPD) is a serious long-term lung disease in which the airflow from the lungs is progressively reduced. By 2030, COPD will become the third cause of mortality and seventh cause of morbidity worldwide. With advances in technology and mobile communications, significant progress in the mobile health (mHealth) sector has been recently observed. Mobile phones with app capabilities (smartphones) are now considered as potential media for the self-management of certain types of diseases such as asthma, cancer, COPD, or cardiovascular diseases. While many mobile apps for patients with COPD are currently found on the market, there is little published material on the effectiveness of most of them, their features, and their adoption in health care settings. The aim of this study was to search the literature for current systems related to COPD and identify any missing links and studies that were carried out to evaluate the effectiveness of COPD mobile apps. In addition, we reviewed existing mHealth apps from different stores in order to identify features that can be considered in the initial design of a COPD support tool to improve health care services and patient outcomes. In total, 206 articles related to COPD management systems were identified from different databases. Irrelevant materials and duplicates were excluded. Of those, 38 articles were reviewed to extract important features. We identified 214 apps from online stores. Following exclusion of irrelevant apps, 48 were selected and 20 of them were downloaded to review some of their common features. Our review found that out of the 20 apps downloaded, 13 (65%, 13/20) had an education section, 5 (25%, 5/20) consisted of medication and guidelines, 6 (30%, 6/20) included a calendar or diary and other features such as reminders or symptom tracking. There was little published material on the effectiveness of the identified COPD apps. Features such as (1) a social networking tool; (2) personalized education; (3) feedback; (4) e-coaching; and (5) psychological motivation to enhance behavioral change were found to be missing in many of the downloaded apps. This paper summarizes the features of a COPD patient-support mobile app that can be taken into consideration for the initial design of an integrated care system to encourage the self-management of their condition at home. ©Drishty D Sobnath, Nada Philip, Reem Kayyali, Shereen Nabhani-Gebara, Barbara Pierscionek, Anouk W Vaes, Martijn A Spruit, Evangelos Kaimakamis. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 20.02.2017.

Improving Classification of Protein Interaction Articles Using Context Similarity-Based Feature Selection.

PubMed

Chen, Yifei; Sun, Yuxing; Han, Bing-Qing

2015-01-01

Protein interaction article classification is a text classification task in the biological domain to determine which articles describe protein-protein interactions. Since the feature space in text classification is high-dimensional, feature selection is widely used for reducing the dimensionality of features to speed up computation without sacrificing classification performance. Many existing feature selection methods are based on the statistical measure of document frequency and term frequency. One potential drawback of these methods is that they treat features separately. Hence, first we design a similarity measure between the context information to take word cooccurrences and phrase chunks around the features into account. Then we introduce the similarity of context information to the importance measure of the features to substitute the document and term frequency. Hence we propose new context similarity-based feature selection methods. Their performance is evaluated on two protein interaction article collections and compared against the frequency-based methods. The experimental results reveal that the context similarity-based methods perform better in terms of the F1 measure and the dimension reduction rate. Benefiting from the context information surrounding the features, the proposed methods can select distinctive features effectively for protein interaction article classification.

ALCOHOLIC HEPATITIS: TRANSLATIONAL APPROACHES TO DEVELOP TARGETED THERAPIES

PubMed Central

Mandrekar, Pranoti; Bataller, Ramon; Tsukamoto, Hidekazu; Gao, Bin

2016-01-01

Alcoholic liver disease (ALD) is a leading cause of liver related mortality worldwide. In contrast to recent advances in therapeutic strategies for patients with viral hepatitis, there is a significant lack of novel therapeutic options for patients with ALD. In particular, there is an urgent need to focus our efforts on effective therapeutic interventions for alcoholic hepatitis (AH), the most severe form of ALD. AH is characterized by an abrupt development of jaundice and complications related to liver insufficiency and portal hypertension in patients with heavy alcohol intake. The mortality of patients with AH is very high (20–50% at 3 months). Available therapies are not effective in many patients and targeted approaches are imminently needed. The development of such therapies requires translational studies in human samples and suitable animal models that reproduce clinical and histological features of AH. In recent years, new animal models that simulate some of the features of human AH have been developed, and translational studies using human samples have identified potential pathogenic factors and histological parameters that predict survival. This review article summarizes the unmet needs for translational studies on the pathogenesis of AH, pre-clinical translational tools, and emerging drug targets to benefit the AH patient. PMID:26940353

Special requirements for electronic health record systems in ophthalmology.

PubMed

Chiang, Michael F; Boland, Michael V; Brewer, Allen; Epley, K David; Horton, Mark B; Lim, Michele C; McCannel, Colin A; Patel, Sayjal J; Silverstone, David E; Wedemeyer, Linda; Lum, Flora

2011-08-01

The field of ophthalmology has a number of unique features compared with other medical and surgical specialties regarding clinical workflow and data management. This has important implications for the design of electronic health record (EHR) systems that can be used intuitively and efficiently by ophthalmologists and that can promote improved quality of care. Ophthalmologists often lament the absence of these specialty-specific features in EHRs, particularly in systems that were developed originally for primary care physicians or other medical specialists. The purpose of this article is to summarize the special requirements of EHRs that are important for ophthalmology. The hope is that this will help ophthalmologists to identify important features when searching for EHR systems, to stimulate vendors to recognize and incorporate these functions into systems, and to assist federal agencies to develop future guidelines regarding meaningful use of EHRs. More broadly, the American Academy of Ophthalmology believes that these functions are elements of good system design that will improve access to relevant information at the point of care between the ophthalmologist and the patient, will enhance timely communications between primary care providers and ophthalmologists, will mitigate risk, and ultimately will improve the ability of physicians to deliver the highest-quality medical care. Proprietary or commercial interest disclosure may be found after the references. Copyright © 2011 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

Normative data for idiomatic expressions.

PubMed

Nordmann, Emily; Jambazova, Antonia A

2017-02-01

Idiomatic expressions such as kick the bucket or go down a storm can differ on a number of internal features, such as familiarity, meaning, literality, and decomposability, and these types of features have been the focus of a number of normative studies. In this article, we provide normative data for a set of Bulgarian idioms and their English translations, and by doing so replicate in a Slavic language the relationships between the ratings previously found in Romance and Germanic languages. Additionally, we compared whether collecting these types of ratings in between-subjects or within-subjects designs affects the data and the conclusions drawn, and found no evidence that design type affects the final outcome. Finally, we present the results of a meta-analysis that summarizes the relationships found across the literature. As in many previous individual studies, we found that familiarity correlates with a number of other features; however, such studies have shown conflicting results concerning literality and decomposability ratings. The meta-analysis revealed reliable relationships of decomposability with a number of other measures, such as familiarity, meaning, and predictability. Conversely, literality was shown to have little to no relationship with any of the other subjective ratings. The implications for these relationships in the context of the wider experimental literature are discussed, with a particular focus on the importance of attaining familiarity ratings for each sample of participants in experimental work.

A mini review on hydrogels classification and recent developments in miscellaneous applications.

PubMed

Varaprasad, Kokkarachedu; Raghavendra, Gownolla Malegowd; Jayaramudu, Tippabattini; Yallapu, Murali Mohan; Sadiku, Rotimi

2017-10-01

Hydrogels are composed of three-dimensional smart and/or hungry networks, which do not dissolve in water but swell considerably in an aqueous medium, demonstrating an extraordinary ability to absorb water into the reticulated structure. Such inherent feature is a subject of considerable scientific research interest which leads to a dominating path in extending their potential in hi-tech applications. Over the past decades, significant progress has been made in the field of hydrogels. Further, explorations are continuously being made in all directions at an accelerated pace for their extensive usage. In view of this, the present review discusses the subject on the miscellaneous hydrogels with regard to their raw materials, methods of fabrication and applications. In addition, this article summarizes the classification of hydrogels, based on their cross-linking and physical states. Lately, a brief outlook on the future prospects of hydrogels is also presented. Copyright © 2017 Elsevier B.V. All rights reserved.

A Comparative Study of Workplace Bullying Among Public and Private Employees in Europe.

PubMed

Ariza-Montes, Antonio; Leal-Rodríguez, Antonio L; Leal-Millán, Antonio G

2015-06-01

Workplace bullying emerges from a set of individual, organizational, and contextual factors. The purpose of this article is hence to identify the influence of these factors among public and private employees. The study is carried out as a statistical-empirical cross-sectional study. The database used was obtained from the 5th European Working Conditions Survey 2010. The results reveal a common core with respect to the factors that determine workplace bullying. Despite this common base that integrates both models, the distinctive features of the harassed employee within the public sector deal with age, full-time work, the greater nighttime associated with certain public service professions, and a lower level of motivation. The present work summarizes a set of implications and proposes that, under normal conditions, workplace bullying could be reduced if job demands are limited and job resources are increased.

Monolayer-Mediated Growth of Organic Semiconductor Films with Improved Device Performance.

PubMed

Huang, Lizhen; Hu, Xiaorong; Chi, Lifeng

2015-09-15

Increased interest in wearable and smart electronics is driving numerous research works on organic electronics. The control of film growth and patterning is of great importance when targeting high-performance organic semiconductor devices. In this Feature Article, we summarize our recent work focusing on the growth, crystallization, and device operation of organic semiconductors intermediated by ultrathin organic films (in most cases, only a monolayer). The site-selective growth, modified crystallization and morphology, and improved device performance of organic semiconductor films are demonstrated with the help of the inducing layers, including patterned and uniform Langmuir-Blodgett monolayers, crystalline ultrathin organic films, and self-assembled polymer brush films. The introduction of the inducing layers could dramatically change the diffusion of the organic semiconductors on the surface and the interactions between the active layer with the inducing layer, leading to improved aggregation/crystallization behavior and device performance.

Nanoarchitectonics from Molecular Units to Living-Creature-Like Motifs.

PubMed

Ariga, Katsuhiko; Mori, Taizo; Shrestha, Lok Kumar

2017-12-04

Important points for the fabrication of functional materials are the creation of nanoscale/molecular-scale units and architecting them into functional materials and systems. Recently, a new conceptual paradigm, nanoarchitectonics, has been proposed to combine nanotechnology and other methodologies including supramolecular chemistry, self-assembly and self-organization to satisfy major features of nanoscience and promote the creation of functional materials and systems. In this account article, our recent research results in materials development based on the nanoarchitectonics concept are summarized in two stories, (i) nanoarchitectonics from fullerenes as the simplest nano-units and (ii) dimension-dependent nanoarchitectonics from various structural units. The former demonstrates creativity of the nanoarchitectonics concept only with simple construction stuffs on materials fabrications, and a wide range of material applicability for the nanoarchitectonics strategy is realized in the latter ones. © 2017 The Chemical Society of Japan & Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Moving in a moving medium: new perspectives on flight

PubMed Central

Shepard, Emily L. C.; Portugal, Steven J.

2016-01-01

One of the defining features of the aerial environment is its variability; air is almost never still. This has profound consequences for flying animals, affecting their flight stability, speed selection, energy expenditure and choice of flight path. All these factors have important implications for the ecology of flying animals, and the ecosystems they interact with, as well as providing bio-inspiration for the development of unmanned aerial vehicles. In this introduction, we touch on the factors that drive the variability in airflows, the scales of variability and the degree to which given airflows may be predictable. We then summarize how papers in this volume advance our understanding of the sensory, biomechanical, physiological and behavioural responses of animals to air flows. Overall, this provides insight into how flying animals can be so successful in this most fickle of environments. This article is part of the themed issue ‘Moving in a moving medium: new perspectives on flight’. PMID:27528772

Loin pain hematuria syndrome

PubMed Central

Zubair, Adeel S.; Salameh, Hassan; Erickson, Stephen B.; Prieto, Mikel

2016-01-01

Loin pain hematuria syndrome (LPHS), first described in 1967, is a rare pain syndrome, which is not well understood. The syndrome is characterized by severe intermittent or persistent flank pain, either unilateral or bilateral, associated with gross or microscopic hematuria. LPHS is a diagnosis of exclusion as there still is not a consensus of validated diagnostic criteria, though several criteria have been proposed. The wide differential diagnosis would suggest a meticulous yet specific diagnostic work-up depending on the individual clinical features and natural history. Several mechanisms regarding the pathophysiology of LPHS have been proposed but without pinpointing the actual causative etiology, the treatment remains symptomatic. Treatment modalities for LPHS are diverse including simple analgesia, opioid analgesic and kidney autotransplantation. This review article summarizes the current understanding regarding the pathophysiology of LPHS along with the steps required for proper diagnosis and a discussion of the different therapeutic approaches for LPHS. PMID:26798473

Muscle, bone, and the Utah paradigm: a 1999 overview.

PubMed

Frost, H M

2000-05-01

The still-evolving Utah paradigm of skeletal physiology supplements former ideas about the control of postnatal bone strength and "mass" in health and disease, on earth and in orbit, and as functions of physical activities including sports. In its view, peak muscle forces on bone dominate control of the biologic mechanisms that control changes in our postnatal whole-bone strength and mass. This contrasts with former ideas that chiefly nonmechanical factors dominate that control and mechanical factors have little influence on it. The newer view begs the question of how such a bone-muscle relationship would work, and the Utah paradigm offers plausible explanations for that. Whereas many biomechanicians, orthopedists, and sports medicine experts might find the newer view sensible, some people in other disciplines may not. This article summarizes some evidence that support the Utah paradigm and the above-stated view and explores some of the paradigm's features and implications.

Application of active magnetic bearings in flexible rotordynamic systems - A state-of-the-art review

NASA Astrophysics Data System (ADS)

Siva Srinivas, R.; Tiwari, R.; Kannababu, Ch.

2018-06-01

In this paper a critical review of literature on applications of Active Magnetic Bearings (AMBs) systems in flexible rotordynamic systems have been presented. AMBs find various applications in rotating machinery; however, this paper mainly focuses on works in vibration suppression and associated with the condition monitoring using AMBs. It briefly introduces reader to the AMB working principle, provides details of various hardware components of a typical rotor-AMB test rig, and presents a background of traditional methods of vibration suppression in flexible rotors and the condition monitoring. It then moves on to summarize the basic features of AMB integrated flexible rotor test rigs available in literature with necessary instrumentation and its main objectives. A couple of lookup tables provide summary of important information of test rigs in papers within the scope of this article. Finally, future directions in AMB research within the paper's scope have been suggested.

Infectious Uveitis

PubMed Central

2015-01-01

Infectious uveitis is one of the most common and visually devastating causes of uveitis in the US and worldwide. This review provides a summary of the identification, treatment, and complications associated with certain forms of viral, bacterial, fungal, helminthic, and parasitic uveitis. In particular, this article reviews the literature on identification and treatment of acute retinal necrosis due to herpes simplex virus, varicella virus, and cytomegalovirus. While no agreed-upon treatment has been identified, the characteristics of Ebola virus panuveitis is also reviewed. In addition, forms of parasitic infection such as Toxoplasmosis and Toxocariasis are summarized, as well as spirochetal uveitis. Syphilitic retinitis is reviewed given its increase in prevalence over the last decade. The importance of early identification and treatment of infectious uveitis is emphasized. Early identification can be achieved with a combination of maintaining a high suspicion, recognizing certain clinical features, utilizing multi-modal imaging, and obtaining specimens for molecular diagnostic testing. PMID:26618074

Clinical laboratory analytics: Challenges and promise for an emerging discipline.

PubMed

Shirts, Brian H; Jackson, Brian R; Baird, Geoffrey S; Baron, Jason M; Clements, Bryan; Grisson, Ricky; Hauser, Ronald George; Taylor, Julie R; Terrazas, Enrique; Brimhall, Brad

2015-01-01

The clinical laboratory is a major source of health care data. Increasingly these data are being integrated with other data to inform health system-wide actions meant to improve diagnostic test utilization, service efficiency, and "meaningful use." The Academy of Clinical Laboratory Physicians and Scientists hosted a satellite meeting on clinical laboratory analytics in conjunction with their annual meeting on May 29, 2014 in San Francisco. There were 80 registrants for the clinical laboratory analytics meeting. The meeting featured short presentations on current trends in clinical laboratory analytics and several panel discussions on data science in laboratory medicine, laboratory data and its role in the larger healthcare system, integrating laboratory analytics, and data sharing for collaborative analytics. One main goal of meeting was to have an open forum of leaders that work with the "big data" clinical laboratories produce. This article summarizes the proceedings of the meeting and content discussed.

Clinical laboratory analytics: Challenges and promise for an emerging discipline

PubMed Central

Shirts, Brian H.; Jackson, Brian R.; Baird, Geoffrey S.; Baron, Jason M.; Clements, Bryan; Grisson, Ricky; Hauser, Ronald George; Taylor, Julie R.; Terrazas, Enrique; Brimhall, Brad

2015-01-01

The clinical laboratory is a major source of health care data. Increasingly these data are being integrated with other data to inform health system-wide actions meant to improve diagnostic test utilization, service efficiency, and “meaningful use.” The Academy of Clinical Laboratory Physicians and Scientists hosted a satellite meeting on clinical laboratory analytics in conjunction with their annual meeting on May 29, 2014 in San Francisco. There were 80 registrants for the clinical laboratory analytics meeting. The meeting featured short presentations on current trends in clinical laboratory analytics and several panel discussions on data science in laboratory medicine, laboratory data and its role in the larger healthcare system, integrating laboratory analytics, and data sharing for collaborative analytics. One main goal of meeting was to have an open forum of leaders that work with the “big data” clinical laboratories produce. This article summarizes the proceedings of the meeting and content discussed. PMID:25774320

Overview of the Helios Version 2.0 Computational Platform for Rotorcraft Simulations

NASA Technical Reports Server (NTRS)

Sankaran, Venkateswaran; Wissink, Andrew; Datta, Anubhav; Sitaraman, Jayanarayanan; Jayaraman, Buvna; Potsdam, Mark; Katz, Aaron; Kamkar, Sean; Roget, Beatrice; Mavriplis, Dimitri;

The sign language skills classroom observation: a process for describing sign language proficiency in classroom settings.

PubMed

Reeves, J B; Newell, W; Holcomb, B R; Stinson, M

2000-10-01

In collaboration with teachers and students at the National Technical Institute for the Deaf (NTID), the Sign Language Skills Classroom Observation (SLSCO) was designed to provide feedback to teachers on their sign language communication skills in the classroom. In the present article, the impetus and rationale for development of the SLSCO is discussed. Previous studies related to classroom signing and observation methodology are reviewed. The procedure for developing the SLSCO is then described. This procedure included (a) interviews with faculty and students at NTID, (b) identification of linguistic features of sign language important for conveying content to deaf students, (c) development of forms for recording observations of classroom signing, (d) analysis of use of the forms, (e) development of a protocol for conducting the SLSCO, and (f) piloting of the SLSCO in classrooms. The results of use of the SLSCO with NTID faculty during a trial year are summarized.

The Spreadsheet in an Educational Setting. Microcomputing Working Paper Series F 84-4.

ERIC Educational Resources Information Center

Wozny, Lucy

This overview of a specific spreadsheet, Microsoft's Multiplan for the Apple Macintosh microcomputer, emphasizes specific features that are important to the academic community, including the mathematical functions of algebra, trigonometry, and statistical analysis. Additional features are summarized, including data formats for both numerical and…

Volcanology by Courier: Science in Stamps.

ERIC Educational Resources Information Center

Glenn, William H.

1981-01-01

Summarized are five activities involving collection of postage stamps picturing volcanoes or related scenes for use as part of or at the conclusion of the study of volcanoes. Activity topics include volcanic features, location of volcanoes, related land features where volcanoes are not located, and making one's own volcano stamps. (DS)

Magazine Educators Consider "Service Journalism" Orientation.

ERIC Educational Resources Information Center

Jeffers, Dennis W.

1990-01-01

Summarizes the debate within magazine journalism education over how much attention to devote to "service journalism," which encompasses informative, how-to articles. Surveys readers of "Angus Journal," a beef industry journal. Suggests a reader preference for service articles over news and human interest content. Reviews the…

An Annotated Bibliography: Using Theories of Self-Regulation to Understand How Adults Learn in Various Contexts

ERIC Educational Resources Information Center

Artino, Anthony R., Jr.

2007-01-01

The present report presents an annotated bibliography of peer-reviewed articles that employed theories of self-regulation to understand how adults learn in various contexts. Seven scholarly articles, published between 2000 and 2006, were reviewed and summarized. Articles reviewed include (1) Self-regulation in a Web-based Course: A Case Study (J.…

Carbon Nanotubes Application in the Extraction Techniques of Pesticides: A Review.

PubMed

Jakubus, Aleksandra; Paszkiewicz, Monika; Stepnowski, Piotr

2017-01-02

Carbon nanotubes (CNTs) are currently one of the most promising groups of materials with some interesting properties, such as lightness, rigidity, high surface area, high mechanical strength in tension, good thermal conductivity or resistance to mechanical damage. These unique properties make CNTs a competitive alternative to conventional sorbents used in analytical chemistry, especially in extraction techniques. The amount of work that discusses the usefulness of CNTs as a sorbent in a variety of extraction techniques has increased significantly in recent years. In this review article, the most important feature and different applications of solid-phase extraction (SPE), including, classical SPE and dispersive SPE using CNTs for pesticides isolation from different matrices, are summarized. Because of high number of articles concerning the applicability of carbon materials to extraction of pesticides, the main aim of proposed publication is to provide updated review of the latest uses of CNTs by covering the period 2006-2015. Moreover, in this review, the recent papers and this one, which are covered in previous reviews, will be addressed and particular attention has been paid on the division of publications in terms of classes of pesticides, in order to systematize the available literature reports.

[Anesthesia in obstetrics: Tried and trusted methods, current standards and new challenges].

PubMed

Kranke, P; Annecke, T; Bremerich, D H; Hanß, R; Kaufner, L; Klapp, C; Ohnesorge, H; Schwemmer, U; Standl, T; Weber, S; Volk, T

2016-01-01

Obstetric analgesia and anesthesia have some specific aspects, which in particular are directly related to pathophysiological alterations during pregnancy and also to the circumstance that two or even more individuals are always affected by complications or therapeutic measures. This review article deals with some evergreens and hot topics of obstetric anesthesia and essential new knowledge on these aspects is described. The article summarizes the talks given at the 16th symposium on obstetric anesthesia organized by the Scientific Committee for Regional Anaesthesia and Obstetric Anaesthesia within the German Society of Anaesthesiology. The topics are in particular, special features and pitfalls of informed consent in the delivery room, challenges in education and training in obstetric anesthesia, expedient inclusion of simulation-assisted training and further education on risk minimization, knowledge and recommendations on fasting for the delivery room and cesarean sections, monitoring in obstetric anesthesia by neuraxial and alternative procedures, the possibilities and limitations of using ultrasound for lumbal epidural catheter positioning in the delivery room, recommended approaches in preparing peridural catheters for cesarean section, basic principles of cardiotocography, postoperative analgesia after cesarean section, the practice of early bonding in the delivery room during cesarean section births and the management of postpartum hemorrhage.

Peripheral Exophytic Oral Lesions: A Clinical Decision Tree

PubMed Central

Safi, Yaser; Jafari, Soudeh

2017-01-01

Diagnosis of peripheral oral exophytic lesions might be quite challenging. This review article aimed to introduce a decision tree for oral exophytic lesions according to their clinical features. General search engines and specialized databases including PubMed, PubMed Central, Medline Plus, EBSCO, Science Direct, Scopus, Embase, and authenticated textbooks were used to find relevant topics by means of keywords such as “oral soft tissue lesion,” “oral tumor like lesion,” “oral mucosal enlargement,” and “oral exophytic lesion.” Related English-language articles published since 1988 to 2016 in both medical and dental journals were appraised. Upon compilation of data, peripheral oral exophytic lesions were categorized into two major groups according to their surface texture: smooth (mesenchymal or nonsquamous epithelium-originated) and rough (squamous epithelium-originated). Lesions with smooth surface were also categorized into three subgroups according to their general frequency: reactive hyperplastic lesions/inflammatory hyperplasia, salivary gland lesions (nonneoplastic and neoplastic), and mesenchymal lesions (benign and malignant neoplasms). In addition, lesions with rough surface were summarized in six more common lesions. In total, 29 entities were organized in the form of a decision tree in order to help clinicians establish a logical diagnosis by a stepwise progression method. PMID:28757870

Mission Impossible? What States with Large Percentages of Rural Schools Tell Us about Federal School Improvement Grants

ERIC Educational Resources Information Center

Scott, Caitlin; McMurrer, Jennifer

2015-01-01

This article summarizes findings and lessons learned about implementing school improvement grant (SIG) initiatives in rural areas of the United States. The study examines state-level survey data based on the proportion of rural schools receiving SIG funds in the fall of 2010 in each state. In addition, the authors summarize related findings from…

Neuromuscular Electrical Stimulation for Motor Restoration in Hemiplegia

PubMed Central

Knutson, Jayme S.; Fu, Michael J.; Sheffler, Lynne R.; Chae, John

2015-01-01

Synopsis This article reviews the most common therapeutic and neuroprosthetic applications of neuromuscular electrical stimulation (NMES) for upper and lower extremity stroke rehabilitation. Fundamental NMES principles and purposes in stroke rehabilitation are explained. NMES modalities used for upper and lower limb rehabilitation are described and efficacy studies are summarized. The evidence for peripheral and central mechanisms of action is also summarized. PMID:26522909

Virtual patients to explore and develop clinical case summary statement skills amongst Japanese resident physicians: a mixed methods study.

PubMed

Heist, Brian S; Kishida, Naoki; Deshpande, Gautam; Hamaguchi, Sugihiro; Kobayashi, Hiroyuki

2016-02-01

In Western clinical training, formulation of a summary statement (SS) is a core exercise for articulation, evaluation, and improvement of clinical reasoning (CR). In Japanese clinical training, structured guidance in developing CR, including opportunity for SS practice, is uncommon, and the present status of case summarization skills is unclear. We used Virtual Patients (VPs) to explore Japanese junior residents' SS styles and the effectiveness of VPs on improving SS quality. All first-year junior resident physicians at 4 residency programs (n = 54) were assigned randomized sequences of 5 VP modules, rolled out at 6 day intervals. During each module, participants free-texted a case summary and then reviewed a model summary. Thematic analysis was used to identify SS styles and each SS was categorized accordingly. Frequency of SS styles, and SS CR quality determined by 1) an internally developed Key Feature rubric and 2) demonstration of semantic qualification, were compared across modules. Four SS styles were identified: numbered features matched to differential diagnoses, differential diagnoses with supportive comments, feature listing, and narrative summarization. From module #1 to #5, significant increases in the narrative summarization SS style (p = 0.016), SS CR quality score (p = 0.021) and percentage of semantically driven SS (p = 0.003) were observed. Our study of Japanese junior residents identified distinct clinical case summary statement styles, and observed adoption of the narrative summarization style and improvement in the CR quality of summary statements during a series of VP cases.

Interventions and controls to prevent emergency service vehicle incidents: A mixed methods review.

PubMed

Bui, David P; Balland, Samantha; Giblin, Casey; Jung, Alesia M; Kramer, Sandy; Peng, Abigail; Aquino, Marie Corazon Ponce; Griffin, Stephanie; French, Dustin D; Pollack Porter, Keshia; Crothers, Steve; Burgess, Jefferey L

2018-06-01

Emergency service vehicle incidents (ESVI), including crashes, rollovers, and roadside struck-by-incidents, are a leading cause of occupational fatality and injury among firefighters and other emergency responders. Though there are numerous strategies and interventions to prevent ESVIs, the evidence base for these strategies is limited and dispersed. The goal of this study was to gather and present a review of evidence-based ESVI interventions. We searched five academic databases for articles published within the last decade featuring interventions to reduce or prevent ESVIs. We interviewed key informants from fire departments serving major metropolitan areas for additional interventions. Interventions from both sources were summarized and data on intervention effectiveness were reported when available. Sixty-five articles were included in the final review and 17 key informant interviews were completed. Most articles focused on vehicle engineering interventions (38%), followed by policy and administration interventions (26%), environmental engineering interventions (19%) and education or training (17%). Most key informants reported policy (49%) and training interventions (29%). Enhanced drivers' training and risk management programs were associated with 19-50% and 19-58% reductions in ESVIs, respectively. Only a limited number of interventions to address ESVIs had adequate outcome data. Based on the available data, training and risk management approaches may be particularly effective approaches to reducing ESVIs. Copyright © 2018 The Authors. Published by Elsevier Ltd.. All rights reserved.

Towards liquid-helium-free, persistent-mode MgB2 MRI magnets: FBML experience

NASA Astrophysics Data System (ADS)

Iwasa, Yukikazu

2017-05-01

In this article I present our experience at the Magnet Technology Division of the MIT Francis Bitter Magnet Laboratory on liquid-helium (LHe)-free, persistent-mode MgB2 MRI magnets. Before reporting on our MgB2 magnets, I first summarize the basic work that we began in the late 1990s to develop LHe-free, high-temperature superconductor (HTS) magnets cooled in solid cryogen—I begin by discussing the enabling feature, particularly of solid nitrogen (SN2), for adiabatic HTS magnets. The next topic is our first LHe-free, SN2-HTS magnet, for which we chose Bi2223 because in the late 1990s Bi2223 was the only HTS available to build an HTS magnet. I then move on to two MgB2 magnets, I and II, developed after discovery of MgB2 in 2000. The SN2-MgB2 Magnet II—0.5 T/240 mm, SN2-cooled, and operated in persistent mode—was completed in January 2016. The final major topic in this article is a tabletop LHe-free, persistent-mode 1.5 T/70 mm SN2-MgB2 ‘finger’ MRI magnet for osteoporosis screening—we expect to begin this project in 2017. Before concluding this article, I present my current view on challenges and prospects for MgB2 MRI magnets.

Towards Liquid-Helium-Free, Persistent-Mode MgB2 MRI Magnets: FBML Experience.

PubMed

Iwasa, Yukikazu

2017-01-01

In this article I present our experience at the Magnet Technology Division of the MIT Francis Bitter Magnet Laboratory on liquid-helium (LHe)-free, persistent-mode MgB 2 MRI magnets. Before reporting on our MgB 2 magnets, I first summarize the basic work that we began in the late 1990s to develop LHe-free, high-temperature superconductor (HTS) magnets cooled in solid cryogen-I begin by discussing the enabling feature, particularly of solid nitrogen (SN2), for adiabatic HTS magnets. The next topic is our first LHe-free, SN2-HTS magnet, for which we chose Bi2223 because in the late 1990s Bi2223 was the only HTS available to build an HTS magnet. I then move on to two MgB 2 magnets, I and II, developed after discovery of MgB 2 in 2000. The SN2-MgB 2 Magnet II-0.5-T/240-mm, SN2-cooled, and operated in persistent mode-was completed in January 2016. The final major topic in this article is a tabletop LHe-free, persistent-mode 1.5-T/70-mm SN2-MgB 2 "finger" MRI magnet for osteoporosis screening-we expect to begin this project in 2017. Before concluding this article, I present my current view on challenges and prospects for MgB 2 MRI magnets.

Towards Liquid-Helium-Free, Persistent-Mode MgB2 MRI Magnets: FBML Experience

PubMed Central

Iwasa, Yukikazu

2017-01-01

In this article I present our experience at the Magnet Technology Division of the MIT Francis Bitter Magnet Laboratory on liquid-helium (LHe)-free, persistent-mode MgB2 MRI magnets. Before reporting on our MgB2 magnets, I first summarize the basic work that we began in the late 1990s to develop LHe-free, high-temperature superconductor (HTS) magnets cooled in solid cryogen—I begin by discussing the enabling feature, particularly of solid nitrogen (SN2), for adiabatic HTS magnets. The next topic is our first LHe-free, SN2-HTS magnet, for which we chose Bi2223 because in the late 1990s Bi2223 was the only HTS available to build an HTS magnet. I then move on to two MgB2 magnets, I and II, developed after discovery of MgB2 in 2000. The SN2-MgB2 Magnet II—0.5-T/240-mm, SN2-cooled, and operated in persistent mode—was completed in January 2016. The final major topic in this article is a tabletop LHe-free, persistent-mode 1.5-T/70-mm SN2-MgB2 “finger” MRI magnet for osteoporosis screening—we expect to begin this project in 2017. Before concluding this article, I present my current view on challenges and prospects for MgB2 MRI magnets. PMID:29568161

Scaling School Turnaround

ERIC Educational Resources Information Center

Herman, Rebecca

2012-01-01

This article explores the research on turning around low performing schools to summarize what we know, what we don't know, and what this means for scaling school turnaround efforts. "School turnaround" is defined here as quick, dramatic gains in academic achievement for persistently low performing schools. The article first considers the…

Making the Most of Multi-Disciplinary Undergraduate Research Conferences

ERIC Educational Resources Information Center

Hill, Jennifer; West, Harry; Kneale, Pauline

2018-01-01

This is the second of two Directions articles, which together offer guidance to help the reader gain the maximum benefit from participating in institutional and national multi-disciplinary undergraduate research conferences. The earlier article introduced undergraduate research conferences, summarized the key benefits of participating in such…

A Concurrent Support Course for Intermediate Algebra

ERIC Educational Resources Information Center

Cooper, Cameron I.

2011-01-01

This article summarizes the creation and implementation of a concurrent support class for TRS 92--Intermediate Algebra, a developmental mathematics course at Fort Lewis College in Durango, Colorado. The concurrent course outlined in this article demonstrates a statistically significant increase in student success rates since its inception.…

Design and Evaluation of the NFL PLAY 60 FITNESSGRAM® Partnership Project

ERIC Educational Resources Information Center

Welk, Gregory J.; Bai, Yang; Saint-Maurice, Pedro F.; Allums-Featherston, Kelly; Candelaria, Norma

2016-01-01

This article describes the conceptual design and evaluation strategies used in the NFL PLAY 60 FITNESSGRAM® Partnership Project, a large participatory research network focused on building effective school physical education programming. The article summarizes the unique participatory design, recruitment methods, programming strategies, and…

Behavioral Assessment and Intervention in Pediatric Diabetes

ERIC Educational Resources Information Center

Wysocki, Tim

2006-01-01

This article reviews the empirical research literature on behavioral assessment and intervention methods in the context of diabetes mellitus in children and adolescents. The review summarizes the pathophysiology, medical management, and monitoring of pediatric type 1 and type 2 diabetes. Next, the article describes common behavioral barriers to…

Television Violence and Children. ERIC/EECE Report.

ERIC Educational Resources Information Center

Cesarone, Bernard

1998-01-01

Summarizes 12 recent documents and journal articles from the ERIC database that discuss topics related to television violence and children. Articles cited address the effects of television violence on child behavior and attitudes at school and home, and methods of reducing the impact of television on children. (JPB)

A Method for Populating the Knowledge Base of AFIT’s Domain-Oriented Application Composition System

DTIC Science & Technology

1993-12-01

Analysis ( FODA ). The approach identifies prominent features (similarities) and distinctive features (differences) of software systems within an... analysis approaches we have summarized, the re- searchers described FODA in sufficient detail to use on large domain analysis projects (ones with...Software Technology Center, July 1991. 18. Kang, Kyo C. and others. Feature-Oriented Domain Analysis ( FODA ) Feasibility Study. Technical Report, Software

COSMIC monthly progress report

NASA Technical Reports Server (NTRS)

1994-01-01

Activities of the Computer Software Management and Information Center (COSMIC) are summarized for the month of April 1994. Tables showing the current inventory of programs available from COSMIC are presented and program processing and evaluation activities are summarized. Five articles were prepared for publication in the NASA Tech Brief Journal. These articles (included in this report) describe the following software items: GAP 1.0 - Groove Analysis Program, Version 1.0; SUBTRANS - Subband/Transform MATLAB Functions for Image Processing; CSDM - COLD-SAT Dynamic Model; CASRE - Computer Aided Software Reliability Estimation; and XOPPS - OEL Project Planner/Scheduler Tool. Activities in the areas of marketing, customer service, benefits identification, maintenance and support, and disseminations are also described along with a budget summary.

The Adult Attachment Projective Picture System: integrating attachment into clinical assessment.

PubMed

George, Carol; West, Malcolm

2011-01-01

This article summarizes the development and validation of the Adult Attachment Projective System (AAP), a measure we developed from the Bowlby-Ainsworth developmental tradition to assess adult attachment status. The AAP has demonstrated excellent concurrent validity with the Adult Attachment Interview (George, Kaplan, & Main, 1984/1985/1996; Main & Goldwyn, 1985-1994; Main, Goldwyn, & Hesse, 2003), interjudge reliability, and test-retest reliability, with no effects of verbal intelligence or social desirability. The AAP coding and classification system and application in clinical and community samples are summarized. Finally, we introduce the 3 other articles that are part of this Special Section and discuss the use of the AAP in therapeutic assessment and treatment.

Advances in mechanisms of allergy.

PubMed

Bochner, Bruce S; Busse, William W

2004-05-01

This review summarizes selected Mechanisms of Allergy articles appearing between 2002 and 2003 in the Journal of Allergy and Clinical Immunology. Articles chosen include those dealing with human airways disease pathophysiology, pharmacology, cell biology, cell recruitment, and genetics, as well as information from allergen challenge models in both human and nonhuman systems. When appropriate, articles from other journals have been included to supplement the topics being presented.

Advances in mechanisms of asthma, allergy, and immunology in 2008.

PubMed

Boyce, Joshua A; Broide, David; Matsumoto, Kenji; Bochner, Bruce S

2009-03-01

This review summarizes selected articles appearing in 2008 in the Journal. Articles chosen include those improving our understanding of mechanisms of allergic diseases by focusing on human basophil, mast cell, and eosinophil biology; IgE and its high-affinity receptor on various cells; novel properties of omalizumab; airways remodeling; and genetics. Articles from other journals have been included to supplement the topics presented.

Operational Features of the Kamehameha Early Education Project. Technical Report #4.

ERIC Educational Resources Information Center

Gallimore, Ronald; And Others

This report summarizes the operational features of the initial phases of the Kamehameha Early Education Project (KEEP). The rationale for KEEP's focus on conducting research on programs similar to those in the public schools rather than on developing radically innovative educational programs is discussed. Start up procedures such as recruitment of…

A Competency-Based Human Resource Development Strategy

ERIC Educational Resources Information Center

Gangani, Noordeen; McLean, Gary N.; Braden, Richard A.

2006-01-01

This article explores some of the major issues in developing and implementing a competency-based human resource development strategy. The article summarizes a brief literature review on how competency models can be developed and implemented to improve employee performance. A case study is presented of American Medical Systems (AMS), a mid-sized…

Success in challenging time: Important lessons learned from the US beekeeping industry

USDA-ARS?s Scientific Manuscript database

The United States plays a leadership role in the global beekeeping and honey industries. This article summarizes the roles of honey bees in agriculture and the key challenges facing the US beekeeping industry as well as innovative solutions to existing problems. The article also provides a review ...

The Perspectives of Policy Researchers: A Synthesis of Special Issue Contributions

ERIC Educational Resources Information Center

Mullin, Christopher M.

2015-01-01

This article summarizes the divergent perspectives found across the 14 articles written by individuals from three types of policy research organizations--think tanks, regional collaborative organizations, and university-based institutes and centers--for this special issue of the "Community College Journal of Research and Practice." It…

Teacher Agency in Educational Reform: Lessons from Social Networks Research

ERIC Educational Resources Information Center

Datnow, Amanda

2012-01-01

This article provides a context for understanding how social networks among teachers support or constrain school improvement in terms of instructional practice, professional development, and educational reform. It comments on the articles in this special issue, summarizing their contributions to the field. This analysis reveals several important…

Cooperative Learning: Smart Pedagogy and Tools for Online and Hybrid Courses

ERIC Educational Resources Information Center

Gradel, Kathleen; Edson, Alden J.

2011-01-01

This article focuses on meshing technology-enhanced learning with cooperative learning pedagogy, to address teaching/learning challenges in higher education online and hybrid courses. Illustrations of implementation are made using coursework exemplars. Start-up solutions and sample applications are summarized. The purposes of this article are to…

Reflective Supervision: Past, Present, and Future

ERIC Educational Resources Information Center

Eggbeer, Linda; Mann, Tammy; Seibel, Nancy

2007-01-01

This article provides a description of the meaning and evolution of reflective supervision. The authors summarize the history of reflective supervision, including ZERO TO THREE's efforts to promote its use as an essential element of professional development in the infant-family field. The article describes the centrality of reflective …

Effective Use of Action-Oriented Studies in Pakistan.

ERIC Educational Resources Information Center

Miles, M.

1991-01-01

This article summarizes results from action-oriented studies carried out at the Mental Heath Centre in Peshawar, Pakistan, dealing with such topics as attitudes toward disability, casual integration, and trends in polio paralysis. The article also considers problems associated with the dissemination of special education and rehabilitation research…

Emergent Characteristics of Effective Cross-Cultural Research: A Review of the Literature

ERIC Educational Resources Information Center

Sullivan, Christopher; Cottone, R. Rocco

2010-01-01

This article identifies characteristics of effective research done in cross-cultural environments; reviews the literature in the years following the publication of Oyserman, Coon, and Kemmelmeier's (2002) seminal article, challenging the basis for the description of cultures as individualistic or collectivistic; and summarizes major issues…

Major publications in the critical care pharmacotherapy literature in 2015.

PubMed

Wong, Adrian; Erdman, Michael; Hammond, Drayton A; Holt, Tara; Holzhausen, Jenna M; Horng, Michelle; Huang, Lori Lynn; Jarvis, Jennifer; Kram, Bridgette; Kram, Shawn; Lesch, Christine; Mercer, Jessica; Rech, Megan A; Rivosecchi, Ryan; Stump, Brian; Teevan, Colleen; Day, Sarah

2017-03-01

Recently published practice guidelines and research reports on pharmacotherapy in critical care patient populations are summarized. The Critical Care Pharmacotherapy Literature Update (CCPLU) Group is composed of over 50 experienced critical care pharmacists who evaluate 31 peer-reviewed journals monthly to identify literature pertaining to pharmacotherapy in critical care populations. Articles are chosen for summarization in a monthly CCPLU Group publication on the basis of applicability and relevance to clinical practice and strength of study design. From January to December 2015, a total of 121 articles were summarized; of these, 3 articles presenting clinical practice guidelines and 12 articles presenting original research findings were objectively selected for inclusion in this review based on their potential to change or reinforce current evidence-based practice. The reviewed guidelines address the management of intracranial hemorrhage (ICH), adult advanced cardiac life support (ACLS) and post-cardiac arrest care, and the management of supraventricular tachycardia (SVT). The reviewed research reports address topics such as nutrition in critically ill adults, administration of β-lactams for severe sepsis, anticoagulant selection in the context of continuous renal replacement therapy, early goal-directed therapy in septic shock, magnesium use for neuroprotection in acute stroke, and progesterone use in patients with traumatic brain injury. Important recent additions to the critical care pharmacy literature include updated joint clinical practice guidelines on the management of spontaneous ICH, ACLS, and SVT. Copyright © 2017 by the American Society of Health-System Pharmacists, Inc. All rights reserved.

Use of a Machine-learning Method for Predicting Highly Cited Articles Within General Radiology Journals.

PubMed

Rosenkrantz, Andrew B; Doshi, Ankur M; Ginocchio, Luke A; Aphinyanaphongs, Yindalon

2016-12-01

This study aimed to assess the performance of a text classification machine-learning model in predicting highly cited articles within the recent radiological literature and to identify the model's most influential article features. We downloaded from PubMed the title, abstract, and medical subject heading terms for 10,065 articles published in 25 general radiology journals in 2012 and 2013. Three machine-learning models were applied to predict the top 10% of included articles in terms of the number of citations to the article in 2014 (reflecting the 2-year time window in conventional impact factor calculations). The model having the highest area under the curve was selected to derive a list of article features (words) predicting high citation volume, which was iteratively reduced to identify the smallest possible core feature list maintaining predictive power. Overall themes were qualitatively assigned to the core features. The regularized logistic regression (Bayesian binary regression) model had highest performance, achieving an area under the curve of 0.814 in predicting articles in the top 10% of citation volume. We reduced the initial 14,083 features to 210 features that maintain predictivity. These features corresponded with topics relating to various imaging techniques (eg, diffusion-weighted magnetic resonance imaging, hyperpolarized magnetic resonance imaging, dual-energy computed tomography, computed tomography reconstruction algorithms, tomosynthesis, elastography, and computer-aided diagnosis), particular pathologies (prostate cancer; thyroid nodules; hepatic adenoma, hepatocellular carcinoma, non-alcoholic fatty liver disease), and other topics (radiation dose, electroporation, education, general oncology, gadolinium, statistics). Machine learning can be successfully applied to create specific feature-based models for predicting articles likely to achieve high influence within the radiological literature. Copyright © 2016 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.

A study of meteor spectroscopy and physics from earth-orbit: A preliminary survey into ultraviolet meteor spectra

NASA Technical Reports Server (NTRS)

Meisel, D. D.

1976-01-01

Preliminary data required to extrapolate available meteor physics information (obtained in the photographic, visual and near ultraviolet spectral regions) into the middle and far ultraviolet are presented. Wavelength tables, telluric attenuation factors, meteor rates, and telluric airglow data are summarized in the context of near-earth observation vehicle parameters using moderate to low spectral resolution instrumentation. Considerable attenuation is given to the problem of meteor excitation temperatures since these are required to predict the strength of UV features. Relative line intensities are computed for an assumed chondritic composition. Features of greatest predicted intensities, the major problems in meteor physics, detectability of UV meteor events, complications of spacecraft motion, and UV instrumentation options are summarized.

Adult hippocampal neurogenesis: an important target associated with antidepressant effects of exercise.

PubMed

Sun, Lina; Sun, Qingshan; Qi, Jinshun

2017-10-26

Depression is a prevalent devastating mental disorder that affects the normal life of patients and brings a heavy burden to whole society. Although many efforts have been made to attenuate depressive/anxiety symptoms, the current clinic antidepressants have limited effects. Scientists have long been making attempts to find some new strategies that can be applied as the alternative antidepressant therapy. Exercise, a widely recognized healthy lifestyle, has been suggested as a therapy that can relieve psychiatric stress. However, how exercise improves the brain functions and reaches the antidepressant target needs systematic summarization due to the complexity and heterogeneous feature of depression. Brain plasticity, especially adult neurogenesis in the hippocampus, is an important neurophysiology to facilitate animals for neurogenesis can occur in not only humans. Many studies indicated that an appropriate level of exercise can promote neurogenesis in the adult brains. In this article, we provide information about the antidepressant effects of exercise and its implications in adult neurogenesis. From the neurogenesis perspective, we summarize evidence about the effects of exercise in enhancing neurogenesis in the hippocampus through regulating growth factors, neurotrophins, neurotransmitters and metabolism as well as inflammations. Taken together, a large number of published works indicate the multiple benefits of exercise in the brain functions of animals, particularly brain plasticity like neurogenesis and synaptogenesis. Therefore, a new treatment method for depression therapy can be developed by regulating the exercise activity.

Interpreting Definiteness in a Second Language without Articles: The Case of L2 Russian

ERIC Educational Resources Information Center

Cho, Jacee; Slabakova, Roumyana

2014-01-01

This article investigates the second language (L2) acquisition of two expressions of the semantic feature [definite] in Russian, a language without articles, by English and Korean native speakers. Within the Feature Reassembly approach (Lardiere, 2009), Slabakova (2009) has argued that reassembling features that are represented overtly in the…

Towards pervasive computing in health care – A literature review

PubMed Central

Orwat, Carsten; Graefe, Andreas; Faulwasser, Timm

2008-01-01

Background The evolving concepts of pervasive computing, ubiquitous computing and ambient intelligence are increasingly influencing health care and medicine. Summarizing published research, this literature review provides an overview of recent developments and implementations of pervasive computing systems in health care. It also highlights some of the experiences reported in deployment processes. Methods There is no clear definition of pervasive computing in the current literature. Thus specific inclusion criteria for selecting articles about relevant systems were developed. Searches were conducted in four scientific databases alongside manual journal searches for the period of 2002 to 2006. Articles included present prototypes, case studies and pilot studies, clinical trials and systems that are already in routine use. Results The searches identified 69 articles describing 67 different systems. In a quantitative analysis, these systems were categorized into project status, health care settings, user groups, improvement aims, and systems features (i.e., component types, data gathering, data transmission, systems functions). The focus is on the types of systems implemented, their frequency of occurrence and their characteristics. Qualitative analyses were performed of deployment issues, such as organizational and personnel issues, privacy and security issues, and financial issues. This paper provides a comprehensive access to the literature of the emerging field by addressing specific topics of application settings, systems features, and deployment experiences. Conclusion Both an overview and an analysis of the literature on a broad and heterogeneous range of systems are provided. Most systems are described in their prototype stages. Deployment issues, such as implications on organization or personnel, privacy concerns, or financial issues are mentioned rarely, though their solution is regarded as decisive in transferring promising systems to a stage of regular operation. There is a need for further research on the deployment of pervasive computing systems, including clinical studies, economic and social analyses, user studies, etc. PMID:18565221

Successful Solutions to SSME/AT Development Turbine Blade Distress

NASA Technical Reports Server (NTRS)

Montgomery, Stuart K.

1999-01-01

As part of the High-Pressure Fuel Turbopump/Alternate Turbopump (HPFTP/AT) turbine blade development program, unique turbine blade design features were implemented to address 2nd stage turbine blade high cycle fatigue distress and improve turbine robustness. Features included the addition of platform featherseal dampers, asymmetric blade tip seal segments, gold plating of the blade attachments, and airfoil tip trailing edge modifications. Development testing shows these features have eliminated turbine blade high cycle fatigue distress and consequently these features are currently planned for incorporation to the flight configuration. Certification testing will begin in 1999. This presentation summarizes these features.

Neuromuscular Electrical Stimulation for Motor Restoration in Hemiplegia.

PubMed

Knutson, Jayme S; Fu, Michael J; Sheffler, Lynne R; Chae, John

2015-11-01

This article reviews the most common therapeutic and neuroprosthetic applications of neuromuscular electrical stimulation (NMES) for upper and lower extremity stroke rehabilitation. Fundamental NMES principles and purposes in stroke rehabilitation are explained. NMES modalities used for upper and lower limb rehabilitation are described, and efficacy studies are summarized. The evidence for peripheral and central mechanisms of action is also summarized. Copyright © 2015 Elsevier Inc. All rights reserved.

Review of numerical models to predict cooling tower performance

DOE Office of Scientific and Technical Information (OSTI.GOV)

Johnson, B.M.; Nomura, K.K.; Bartz, J.A.

1987-01-01

Four state-of-the-art computer models developed to predict the thermal performance of evaporative cooling towers are summarized. The formulation of these models, STAR and TEFERI (developed in Europe) and FACTS and VERA2D (developed in the U.S.), is summarized. A fifth code, based on Merkel analysis, is also discussed. Principal features of the codes, computation time and storage requirements are described. A discussion of model validation is also provided.

Noonan Syndrome Complicated by Primary Pulmonary Lymphangiectasia.

PubMed

Ford, Jaclyn Jo; Trotter, Carol W

2015-01-01

Noonan syndrome is a genetic disorder that has several features common to other conditions, making diagnosis a challenge. This column summarizes the case of a neonate with an atypical presentation of Noonan syndrome involving a fatal type of lymphangiectasia resulting in persistent pleural effusions. Radiographic features of this condition are presented along with the complexities of diagnosis and treatment.

Review of Selected Dissertations Addressing School Public Relations, Administrator Communication, and Conflict Resolution

ERIC Educational Resources Information Center

Decman, John M.; Simieou, Felix, III

2009-01-01

This article is an extension to Kowalski's (2005) identification of possible lines of scholarly inquiry into themes related to schools and public relations. The article first cites professional accreditation standards for educational leaders as significant factors in providing a framework for increased scholarly inquiry. It then summarizes the…

The JAL Guide to the Professional Literature

ERIC Educational Resources Information Center

Reiner, Laura; Smith, Allen

2004-01-01

The purpose of this Guide is to highlight for academic librarians the important articles, books, Web sites, and reviews that come to the attention of the editors. The articles, notes, and reviews summarized below are from within and without the library profession, and although international in scope, are limited to English language publications,…

The JAL Guide to the Professional Literature

ERIC Educational Resources Information Center

Reiner, Laura; Smith, Allen

2004-01-01

The purpose of this Guide is to highlight for academic librarians the important articles, books, Web sites, and reviews that come to the attention of the editors. The articles, notes, and reviews summarized below are from within and without the library profession and although international in scope are limited to English language publications,…

How Can Organizational and Sociocultural Learning Theories Shed Light on District Instructional Reform?

ERIC Educational Resources Information Center

Knapp, Michael S.

2008-01-01

This article explores how organizational and sociocultural learning theories can help us to understand the problem of system-wide instructional reform in school districts. After briefly summarizing the central challenges facing leaders in such districts, the article reviews key ideas associated with each theoretical lens and considers how each…

The Responding Reader: Nine New Approaches to Teaching Literature.

ERIC Educational Resources Information Center

Davis, Ken, Ed.

1982-01-01

Articles in this journal issue explore the relationship between the reader and the literature text, and discuss ways that instruction can enhance reader response to that literature. Following an introduction summarizing the nine articles, the titles and their authors are as follows: (1) "It Is the Poem That I Remake: Using Kenneth Burke's…

An Annotated Bibliography of Verbal Behavior Scholarship Published outside of "The Analysis of Verbal Behavior": 2014

ERIC Educational Resources Information Center

Carr, James E.; Nosik, Melissa R.; Lechago, Sarah A.; Phillips, Lauren

2015-01-01

This annotated bibliography summarizes journal articles on verbal behavior published outside of "The Analysis of Verbal Behavior," the primary journal for scholarship in this area. Seventeen such articles were published in 2014 and are annotated as a resource for practitioners, researchers, and educators.

A Systematic Review of Research on the Flipped Learning Method in Engineering Education

ERIC Educational Resources Information Center

Karabulut-Ilgu, Aliye; Jaramillo Cherrez, Nadia; Jahren, Charles T.

2018-01-01

The purpose of this article is to describe the current state of knowledge and practice in the flipped learning approach in engineering education and to provide guidance for practitioners by critically appraising and summarizing existing research. This article is a qualitative synthesis of quantitative and qualitative research investigating the…

The Education of Juveniles in Detention: Policy Considerations and Infrastructure Development

ERIC Educational Resources Information Center

Geib, Catherine Foley; Chapman, John F.; D'Amaddio, Amy H.; Grigorenko, Elena L.

2011-01-01

This article presents a discussion of the state of affairs pertaining to educating juvenile justice-involved youth. It summarizes general observations regarding the schooling of juveniles in pre-trial and post-trial incarceration settings, as well as, juveniles on probation or in community settings. The article selectively presents relevant…

Biliteracy Teachers' Self-Reflections of Their Accounts while Student Teaching Abroad: Speaking from "the Other Side"

ERIC Educational Resources Information Center

Quezada, Reyes L.; Alfaro, Cristina

2007-01-01

In an article published in the "International Education Journal" entitled "Beyond Educational Tourism: Lessons Learned While Student Teaching Abroad," Quezada (2005) provides an overview of the literature regarding student teaching abroad experiences. This article summarizes his literature review and applies the findings to a…

Putting Universal Design for Learning on the Higher Ed Agenda

ERIC Educational Resources Information Center

Gradel, Kathleen; Edson, Alden J.

2010-01-01

This article provides an overview of how Universal Design for Learning (UDL) applies to higher education. Illustrations of UDL implementation are made, using both campus models of systemic change and coursework exemplars. Start-up solutions and sample applications are summarized. The purposes of this article are to: provide an overview of UDL,…

A Three-Stage Model for Implementing Focused Written Corrective Feedback

ERIC Educational Resources Information Center

Chong, Sin Wang

2017-01-01

This article aims to show how the findings from written corrective feedback (WCF) research can be applied in practice. One particular kind of WCF--focused WCF--is brought into the spotlight. The article first summarizes major findings from focused WCF research to reveal the potential advantages of correcting a few preselected language items…

Seeing Is Believing: The Effect of Brain Images on Judgments of Scientific Reasoning

ERIC Educational Resources Information Center

McCabe, David P.; Castel, Alan D.

2008-01-01

Brain images are believed to have a particularly persuasive influence on the public perception of research on cognition. Three experiments are reported showing that presenting brain images with articles summarizing cognitive neuroscience research resulted in higher ratings of scientific reasoning for arguments made in those articles, as compared…

Lessons from Our Kissing Cousins: Third Culture Kids and Gifted Children

ERIC Educational Resources Information Center

Sheard, Wenda

2008-01-01

This article describes characteristics shared by "third culture kids" (TCKs) and gifted children and summarizes lessons to be learned from the two communities. Some of the lessons are from TCKs themselves; the article includes quotes from students the author has taught in recent years. Pedagogical lessons for raising the global awareness…

Using clustering and a modified classification algorithm for automatic text summarization

NASA Astrophysics Data System (ADS)

Aries, Abdelkrime; Oufaida, Houda; Nouali, Omar

2013-01-01

In this paper we describe a modified classification method destined for extractive summarization purpose. The classification in this method doesn't need a learning corpus; it uses the input text to do that. First, we cluster the document sentences to exploit the diversity of topics, then we use a learning algorithm (here we used Naive Bayes) on each cluster considering it as a class. After obtaining the classification model, we calculate the score of a sentence in each class, using a scoring model derived from classification algorithm. These scores are used, then, to reorder the sentences and extract the first ones as the output summary. We conducted some experiments using a corpus of scientific papers, and we have compared our results to another summarization system called UNIS.1 Also, we experiment the impact of clustering threshold tuning, on the resulted summary, as well as the impact of adding more features to the classifier. We found that this method is interesting, and gives good performance, and the addition of new features (which is simple using this method) can improve summary's accuracy.

Interface between black-footed ferret research and operational conservation

USGS Publications Warehouse

Biggins, Dean E.; Livieri, Travis M.; Breck, Stewart W.

2011-01-01

Questions and problems that emerged during operational conservation of black-footed ferrets (Mustela nigripes) have been addressed by a wide variety of studies. Early results from such studies often were communicated orally during meetings of recovery groups and in written form using memoranda, unpublished reports, and theses. Typically, implementation of results preceded their publication in widely distributed journals. Many of these studies eventually were published in journals, and we briefly summarize the contents of 8 volumes and special features of journals that have been dedicated to the biology of ferrets and issues in ferret recovery. This year marks the 30th anniversary of rediscovery of the black-footed ferret, and the 7 papers of the following Special Feature summarize data collected over nearly that span of time.

Major publications in the critical care pharmacotherapy literature: January-December 2014.

PubMed

Day, Sarah A; Cucci, Michaelia; Droege, Molly E; Holzhausen, Jenna M; Kram, Bridgette; Kram, Shawn; Pajoumand, Mehrnaz; Parker, Christine R; Patel, Mona K; Peitz, Gregory J; Poore, Alia; Turck, Charles J; Van Berkel, Megan A; Wong, Adrian; Zomp, Amanda; Rech, Megan A

2015-11-15

Nine recently published articles and one guideline with important implications for critical care pharmacy practice are summarized. The Critical Care Pharmacotherapy Literature Update (CCPLU) group includes more than 40 experienced critical care pharmacists across the United States. Group members monitor 29 peer-reviewed journals on an ongoing basis to identify literature relevant to pharmacy practice in the critical care setting. After evaluation by CCPLU group members, selected articles are chosen for summarization and distribution to group members nationwide based on applicability to practice, relevance, and study design and strength. Hundreds of relevant articles were evaluated by the group in 2014, of which 114 were summarized and disseminated to CCPLU group members. From among those 114 publications, 10 deemed to be of particularly high utility to the critical care practitioner were selected for inclusion in this review for their potential to change practice or reinforce current evidence-based practice. One of the selected articles presents updated recommendations on the management of patients with atrial fibrillation (AF); the other 9 address topics such as albumin replacement in patients with severe sepsis, use of enteral statins for acute respiratory distress syndrome, fibrinolysis for patients with intermediate-risk pulmonary embolism, the use of unfractionated heparin versus bivalirudin for primary percutaneous coronary intervention, and early protocol-based care for septic shock. There were many important additions to the critical care pharmacotherapy literature in 2014, including a joint guideline for the management of AF and reports of clinical trials. Copyright © 2015 by the American Society of Health-System Pharmacists, Inc. All rights reserved.

Major publications in the critical care pharmacotherapy literature: January-December 2013.

PubMed

Rech, Megan A; Day, Sarah A; Kast, Jenna M; Donahey, Elisabeth E; Pajoumand, Mehrnaz; Kram, Shawn J; Erdman, Michael J; Peitz, Gregory J; Allen, John M; Palmer, Allison; Kram, Bridgette; Harris, Serena A; Turck, Charles J

2015-02-01

Ten recently published articles with important implications for critical care pharmacotherapy are summarized. The Critical Care Pharmacotherapy Literature Update (CCPLU) group is a national assembly of experienced intensive care unit (ICU) pharmacists across the United States. Group members monitor 25 peer-reviewed journals on an ongoing basis to identify literature relevant to pharmacy practice in the critical care setting. After evaluation by CCPLU group members, selected articles are chosen for summarization and distribution to group members nationwide based on (1) applicability to critical care practice, (2) relevance to pharmacy practitioners, and (3) quality of evidence or research methodology. Hundreds of relevant articles were evaluated by the group during the period January-December 2013, of which 98 were summarized and disseminated nationally to CCPLU group members. Among those 98 publications, 10 deemed to be of particularly high utility to critical care practitioners were included in this review. The 10 articles address topics such as rapid lowering of blood pressure in patients with intracranial hemorrhage, adjunctive therapy to prevent renal injury due to acute heart failure, triple-drug therapy to improve neurologic outcomes after cardiac arrest, and continuous versus intermittent infusion of β-lactam antibiotics in severe sepsis. There were many important additions to the critical care pharmacotherapy literature in 2013, including an updated guideline on the management of myocardial infarction and reports on advances in research focused on improving outcomes in patients with stroke or cardiac arrest and preventing the spread of drug-resistant pathogens in the ICU. Copyright © 2015 by the American Society of Health-System Pharmacists, Inc. All rights reserved.

Automatic analysis of medical dialogue in the home hemodialysis domain: structure induction and summarization.

PubMed

Lacson, Ronilda C; Barzilay, Regina; Long, William J

2006-10-01

Spoken medical dialogue is a valuable source of information for patients and caregivers. This work presents a first step towards automatic analysis and summarization of spoken medical dialogue. We first abstract a dialogue into a sequence of semantic categories using linguistic and contextual features integrated in a supervised machine-learning framework. Our model has a classification accuracy of 73%, compared to 33% achieved by a majority baseline (p<0.01). We then describe and implement a summarizer that utilizes this automatically induced structure. Our evaluation results indicate that automatically generated summaries exhibit high resemblance to summaries written by humans. In addition, task-based evaluation shows that physicians can reasonably answer questions related to patient care by looking at the automatically generated summaries alone, in contrast to the physicians' performance when they were given summaries from a naïve summarizer (p<0.05). This work demonstrates the feasibility of automatically structuring and summarizing spoken medical dialogue.

Regulatory effects of cotranscriptional RNA structure formation and transitions.

PubMed

Liu, Sheng-Rui; Hu, Chun-Gen; Zhang, Jin-Zhi

2016-09-01

RNAs, which play significant roles in many fundamental biological processes of life, fold into sophisticated and precise structures. RNA folding is a dynamic and intricate process, which conformation transition of coding and noncoding RNAs form the primary elements of genetic regulation. The cellular environment contains various intrinsic and extrinsic factors that potentially affect RNA folding in vivo, and experimental and theoretical evidence increasingly indicates that the highly flexible features of the RNA structure are affected by these factors, which include the flanking sequence context, physiochemical conditions, cis RNA-RNA interactions, and RNA interactions with other molecules. Furthermore, distinct RNA structures have been identified that govern almost all steps of biological processes in cells, including transcriptional activation and termination, transcriptional mutagenesis, 5'-capping, splicing, 3'-polyadenylation, mRNA export and localization, and translation. Here, we briefly summarize the dynamic and complex features of RNA folding along with a wide variety of intrinsic and extrinsic factors that affect RNA folding. We then provide several examples to elaborate RNA structure-mediated regulation at the transcriptional and posttranscriptional levels. Finally, we illustrate the regulatory roles of RNA structure and discuss advances pertaining to RNA structure in plants. WIREs RNA 2016, 7:562-574. doi: 10.1002/wrna.1350 For further resources related to this article, please visit the WIREs website. © 2016 Wiley Periodicals, Inc.

Expecting the holistic regulation from Chinese medicine based on the "solar system" hypothesis of ischemic heart disease.

PubMed

Luo, Jing; Wang, An-Lu; Xu, Hao; Shi, Da-Zhuo; Chen, Ke-Ji

2016-11-01

Stenosis of the coronary artery has been considered as an essential component of ischemic heart disease (IHD). Consequently, revascularization [e.g., percutaneous coronary intervention (PCI) and coronary artery bypass] has been the primary therapeutic approach to IHD. Such strategy has indeed revolutionized the management of IHD patients. However, not all patients with myocardial ischemia have visible coronary stenosis. Moreover, cardiovascular events occur in nearly 20% patients with stable coronary artery disease who have undergone PCI. The recently proposed "solar system" hypothesis of IHD postulates that coronary stenosis is only one (albeit important) of its features. Mechanistic contribution and clinical implication of multiple pathophysiological processes beyond coronary stenosis are highlighted in this hypothesis. On the basis of a holistic regulation and individualized medicine, Chinese medicine (CM) has been used in the real-world setting to manage a variety of diseases, including IHD, for more than two thousands years. In this article, we summarize the evidence of CM that supports the "solar system" IHD hypothesis, and argue for a comprehensive approach to IHD. At the theoretical level, the central features of this approach include a holistic view of disease and human subjects, as well as individualized medicine. At the practical level, this approach emphasizes anoxia-tolerance and self-healing.

Patterns of Revision in Online Writing: A Study of Wikipedia's Featured Articles

ERIC Educational Resources Information Center

Jones, John

2008-01-01

This study examines the revision histories of 10 Wikipedia articles nominated for the site's Featured Article Class (FAC), its highest quality rating, 5 of which achieved FAC and 5 of which did not. The revisions to each article were coded, and the coding results were combined with a descriptive analysis of two representative articles in order to…

THz Imaging of Skin Burn: Seeing the Unseen—An Overview

PubMed Central

Dutta, Moumita; Bhalla, Amar S.; Guo, Ruyan

2016-01-01

Significance: This review article puts together all the studies performed so far in realizing terahertz (THz) spectra as a probing mechanism for burn evaluation, summarizing their experimental conditions, observations, outcomes, merits, and demerits, along with a comparative discussion of other currently used technologies to present the state of art in a condensed manner. The key features of this noncontact investigation technique like its precise burn depth analysis and the approaches it follows to convert the probed data into a quantitative measure have also been discussed in this article. Recent Advances: The current research developments in THz regime observed in device design technologies (like THz time domain spectrometer, quantum cascade THz lasers, THz single-photon detectors, etc.) and in understanding its unique properties (like nonionizing nature, penetrability through dry dielectrics, etc.) have motivated the research world to realize THz window as a potential candidate for burn detection. Critical Issues: Application of appropriate medical measure for burn injury is primarily subjective to proper estimation of burn depth. Tool modality distinguishing between partial and full-thickness burn contributing toward correct medical care is indeed awaited. Future Directions: The overview of THz imaging as a burn assessment tool as provided in this article will certainly help in further nurturing of this emerging diagnostic technique particularly in improving its detection and accompanied image processing methods so that the minute nuances captured by the THz beam can be correlated with the physiological–anatomical changes in skin structures, caused by burn, for better sensitivity, resolution, and quantitative analysis. PMID:27602253

THz Imaging of Skin Burn: Seeing the Unseen-An Overview.

PubMed

Dutta, Moumita; Bhalla, Amar S; Guo, Ruyan

2016-08-01

Significance: This review article puts together all the studies performed so far in realizing terahertz (THz) spectra as a probing mechanism for burn evaluation, summarizing their experimental conditions, observations, outcomes, merits, and demerits, along with a comparative discussion of other currently used technologies to present the state of art in a condensed manner. The key features of this noncontact investigation technique like its precise burn depth analysis and the approaches it follows to convert the probed data into a quantitative measure have also been discussed in this article. Recent Advances: The current research developments in THz regime observed in device design technologies (like THz time domain spectrometer, quantum cascade THz lasers, THz single-photon detectors, etc.) and in understanding its unique properties (like nonionizing nature, penetrability through dry dielectrics, etc.) have motivated the research world to realize THz window as a potential candidate for burn detection. Critical Issues: Application of appropriate medical measure for burn injury is primarily subjective to proper estimation of burn depth. Tool modality distinguishing between partial and full-thickness burn contributing toward correct medical care is indeed awaited. Future Directions: The overview of THz imaging as a burn assessment tool as provided in this article will certainly help in further nurturing of this emerging diagnostic technique particularly in improving its detection and accompanied image processing methods so that the minute nuances captured by the THz beam can be correlated with the physiological-anatomical changes in skin structures, caused by burn, for better sensitivity, resolution, and quantitative analysis.

10 years experience with pioneering open access publishing in health informatics: the Journal of Medical Internet Research (JMIR).

PubMed

Eysenbach, Gunther

2010-01-01

Peer-reviewed journals remain important vehicles for knowledge transfer and dissemination in health informatics, yet, their format, processes and business models are changing only slowly. Up to the end of last century, it was common for individual researchers and scientific organizations to leave the business of knowledge transfer to professional publishers, signing away their rights to the works in the process, which in turn impeded wider dissemination. Traditional medical informatics journals are poorly cited and the visibility and uptake of articles beyond the medical informatics community remain limited. In 1999, the Journal of Medical Internet Research (JMIR; http://www.jmir.org) was launched, featuring several innovations including 1) ownership and copyright retained by the authors, 2) electronic-only, "lean" non-for-profit publishing, 3) openly accessible articles with a reversed business model (author pays instead of reader pays), 4) technological innovations such as automatic XML tagging and reference checking, on-the-fly PDF generation from XML, etc., enabling wide distribution in various bibliographic and full-text databases. In the past 10 years, despite limited resources, the journal has emerged as a leading journal in health informatics, and is presently ranked the top journal in the medical informatics and health services research categories by impact factor. The paper summarizes some of the features of the Journal, and uses bibliometric and access data to compare the influence of the Journal on the discipline of medical informatics and other disciplines. While traditional medical informatics journals are primarily cited by other Medical Informatics journals (33%-46% of citations), JMIR papers are to a more often cited by "end-users" (policy, public health, clinical journals), which may be partly attributable to the "open access advantage".

Using the Feature Film "American History X" To Teach Principles of Self-Concept in the Introduction to Interpersonal Communication Course.

ERIC Educational Resources Information Center

Siddens, Paul J., III

This paper explores possibilities of using the feature film, "American History X," to illustrate and assist in teaching principles of self-concept in an introduction to interpersonal communication course. The paper: (1) summarizes the plot of the film; (2) outlines and defines principles of self-concept that can be discussed in…

Proteome-wide Subcellular Topologies of E. coli Polypeptides Database (STEPdb)*

PubMed Central

Orfanoudaki, Georgia; Economou, Anastassios

2014-01-01

Cell compartmentalization serves both the isolation and the specialization of cell functions. After synthesis in the cytoplasm, over a third of all proteins are targeted to other subcellular compartments. Knowing how proteins are distributed within the cell and how they interact is a prerequisite for understanding it as a whole. Surface and secreted proteins are important pathogenicity determinants. Here we present the STEP database (STEPdb) that contains a comprehensive characterization of subcellular localization and topology of the complete proteome of Escherichia coli. Two widely used E. coli proteomes (K-12 and BL21) are presented organized into thirteen subcellular classes. STEPdb exploits the wealth of genetic, proteomic, biochemical, and functional information on protein localization, secretion, and targeting in E. coli, one of the best understood model organisms. Subcellular annotations were derived from a combination of bioinformatics prediction, proteomic, biochemical, functional, topological data and extensive literature re-examination that were refined through manual curation. Strong experimental support for the location of 1553 out of 4303 proteins was based on 426 articles and some experimental indications for another 526. Annotations were provided for another 320 proteins based on firm bioinformatic predictions. STEPdb is the first database that contains an extensive set of peripheral IM proteins (PIM proteins) and includes their graphical visualization into complexes, cellular functions, and interactions. It also summarizes all currently known protein export machineries of E. coli K-12 and pairs them, where available, with the secretory proteins that use them. It catalogs the Sec- and TAT-utilizing secretomes and summarizes their topological features such as signal peptides and transmembrane regions, transmembrane topologies and orientations. It also catalogs physicochemical and structural features that influence topology such as abundance, solubility, disorder, heat resistance, and structural domain families. Finally, STEPdb incorporates prediction tools for topology (TMHMM, SignalP, and Phobius) and disorder (IUPred) and implements the BLAST2STEP that performs protein homology searches against the STEPdb. PMID:25210196

New Developments in Breast Cancer Screening and Treatment.

PubMed

Tilstra, Sarah; McNeil, Melissa

2017-01-01

The clinical update serves as a brief review of recently published, high-impact, and potentially practice-changing journal articles summarized for our readers. In this clinical update, we selected top recent articles regarding breast health that may change the clinical practice of women's health providers. We identified articles by reviewing high-impact medical and women's health journals as well as national practice guidelines. Three of our articles are dedicated to the rapid changes in breast cancer screening. With regard to breast cancer treatment, we focused on two articles that impact who we treat with traditional aggressive regimens.

Future Trends in the Application and Impact of Psychopharmacology within the School Setting

ERIC Educational Resources Information Center

Noggle, Chad A.

2009-01-01

The number of children and adolescents using prescription medications is continually climbing. The preceding articles have offered discussions on a multitude of areas within this subject matter. This article will serve to summarize some of those points raised with particular emphasis on where we go from here in terms of training and professional…

Reflections on "A Review of Trends in Serious Gaming"

ERIC Educational Resources Information Center

Tobias, Sigmund; Fletcher, J. D.

2012-01-01

This article briefly summarizes findings from a review of 95 empirical studies of games used in instruction. The article suggests that such efforts are best assessed as transfer from game play to performance on external tasks that are targeted by the instruction. Review findings suggest that such transfer may be expected only if the cognitive…

The Distress Disclosure Index: A Research Review and Multitrait-Multimethod Examination

ERIC Educational Resources Information Center

Kahn, Jeffrey H.; Hucke, Brandy E.; Bradley, Allyson M.; Glinski, Austin J.; Malak, Brittany L.

2012-01-01

The Distress Disclosure Index (DDI; J. H. Kahn & R. M. Hessling, 2001) is a brief self-report measure of one's tendency to disclose personally distressing information. The purpose of this article was to summarize what is known about the DDI, present new validity evidence, and make recommendations for use of the DDI. This article reviews research…

Maintaining the Hegemonic Masculinity through Selective Attachment, Homophobia, and Gay-Baiting in Schools: Challenges to Intervention

ERIC Educational Resources Information Center

Tharinger, Deborah J.

2008-01-01

In this commentary, the author summarizes the research findings of the four articles from this special issue of "School Psychology Review," titled "Sexual Orientation, Homophobia, Bullying, and Psychological Sequelae in Adolescents: Research and Practice Findings," as well as suggestions for intervention offered by the authors of the articles. She…

Second and Foreign Language Assessment

ERIC Educational Resources Information Center

Purpura, James E.

2016-01-01

This article summarizes some of the main issues, concerns, and debates that have ensued over the years in the field of L2 assessment and shows how past concerns have shaped contemporary L2 assessment research and practice. The article first describes what L2 assessment is and what it entails, arguing that notions of L2 assessment have been…

Getting to Scale: Evidence, Professionalism, and Community

ERIC Educational Resources Information Center

Slavin, Robert E.

2016-01-01

Evidence-based reform, in which proven programs are scaled up to reach many students, is playing an increasing role in American education. This article summarizes articles in this issue to explain how Reading Recovery has managed to sustain itself and go to scale over more than 30 years. It argues that Reading Recovery has succeeded due to a focus…

How to Report Exotic Animal Research.

PubMed

Di Girolamo, Nicola; Winter, Alexandra L

2017-09-01

Reporting the results of primary research is a key step in knowledge creation. Many well-conducted studies are rejected by journal editors, criticized by peers, or unsuitable for systematic reviewers because of poor reporting. This article summarizes the most important methodological items to report when writing an original research article. Copyright © 2017 Elsevier Inc. All rights reserved.

Application of Communications Satellites to Educational Development. Final Technical Report, September 1, 1969-August 31, 1975.

ERIC Educational Resources Information Center

Morgan, Robert P.

Research is summarized in a brief final report built around a four-section bibliography. The first section lists periodic progress reports and articles which provide an overview of the program, including articles which pertain primarily to educational rather than technical aspects of satellite utilization. Theses carried out in the fields of…

Listening to Neglected Voices - American Indian Perspectives on Natural Resource Management

Treesearch

David N. Bengston

2004-01-01

Forestry agencies must ensure that the views of all citizens in our increasingly diverse society are included in decisionmaking. But gaining clear insights into the perspectives of ethnic and minority communities is often difficult. This article summarizes an analysis of news articles about resource management issues written by American Indians and published in Indian...

Ecosystem Services Linking People to Coastal Habitats ...

EPA Pesticide Factsheets

Background/Question/Methods: There is a growing need to incorporate and prioritize ecosystem services/condition information into land-use decision making. While there are a number of place-based studies looking at how land-use decisions affect the availability and delivery of coastal services, many of these methods require data, funding and/or expertise that may be inaccessible to many coastal communities. Using existing classification standards for beneficiaries and coastal habitats, (i.e., Final Ecosystem Goods and Services Classification System (FEGS-CS) and Coastal and Marine Ecological Classification Standard (CMECS)), a comprehensive literature review was coupled with a “weight of evidence” approach to evaluate linkages between beneficiaries and coastal habitat features most relevant to community needs. An initial search of peer-reviewed journal articles was conducted using JSTOR and ScienceDirect repositories identifying sources that provide evidence for coastal beneficiary:habitat linkages. Potential sources were further refined based on a double-blind review of titles, abstracts, and full-texts, when needed. Articles in the final list were then scored based on habitat/beneficiary specificity and data quality (e.g., indirect evidence from literature reviews was scored lower than direct evidence from case studies with valuation results). Scores were then incorporated into a weight of evidence framework summarizing the support for each benefici

Systematic literature reviews and meta-analyses: part 6 of a series on evaluation of scientific publications.

PubMed

Ressing, Meike; Blettner, Maria; Klug, Stefanie J

2009-07-01

Because of the rising number of scientific publications, it is important to have a means of jointly summarizing and assessing different studies on a single topic. Systematic literature reviews, meta-analyses of published data, and meta-analyses of individual data (pooled reanalyses) are now being published with increasing frequency. We here describe the essential features of these methods and discuss their strengths and weaknesses. This article is based on a selective literature search. The different types of review and meta-analysis are described, the methods used in each are outlined so that they can be evaluated, and a checklist is given for the assessment of reviews and meta-analyses of scientific articles. Systematic literature reviews provide an overview of the state of research on a given topic and enable an assessment of the quality of individual studies. They also allow the results of different studies to be evaluated together when these are inconsistent. Meta-analyses additionally allow calculation of pooled estimates of an effect. The different types of review and meta-analysis are discussed with examples from the literature on one particular topic. Systematic literature reviews and meta-analyses enable the research findings and treatment effects obtained in different individual studies to be summed up and evaluated.

A review of principles in design and usability testing of tactile technology for individuals with visual impairments.

PubMed

Horton, Emily L; Renganathan, Ramkesh; Toth, Bryan N; Cohen, Alexa J; Bajcsy, Andrea V; Bateman, Amelia; Jennings, Mathew C; Khattar, Anish; Kuo, Ryan S; Lee, Felix A; Lim, Meilin K; Migasiuk, Laura W; Zhang, Amy; Zhao, Oliver K; Oliveira, Marcio A

2017-01-01

To lay the groundwork for devising, improving, and implementing new technologies to meet the needs of individuals with visual impairments, a systematic literature review was conducted to: a) describe hardware platforms used in assistive devices, b) identify their various applications, and c) summarize practices in user testing conducted with these devices. A search in relevant EBSCO databases for articles published between 1980 and 2014 with terminology related to visual impairment, technology, and tactile sensory adaptation yielded 62 articles that met the inclusion criteria for final review. It was found that while earlier hardware development focused on pin matrices, the emphasis then shifted toward force feedback haptics and accessible touch screens. The inclusion of interactive and multimodal features has become increasingly prevalent. The quantity and consistency of research on navigation, education, and computer accessibility suggest that these are pertinent areas of need for the visually impaired community. Methodologies for usability testing ranged from case studies to larger cross-sectional studies. Many studies used blindfolded sighted users to draw conclusions about design principles and usability. Altogether, the findings presented in this review provide insight on effective design strategies and user testing methodologies for future research on assistive technology for individuals with visual impairments.

Recent Advances on Carbon Nanospheres. Synthetic Routes and Applications

DOE PAGES

Zhang, Pengfei; Qiao, Zhenan; Dai, Sheng

2015-04-02

Carbon-based materials are the most popular material types in both fundamental research and industrial applications, partly because of their well-controlled nano-morphologies. In the past two decades, we have witnessed a number of breakthroughs in carbon research: fullerenes, carbon nanotubes, and more recently graphene. Nowadays, carbon nanospheres are attracting more and more attention worldwide due to their excellent performance in various fields: drug delivery, heterogeneous catalysis, encapsulation of support and electrode materials. Actually, spherical carbon is an old material, whereas controlling carbon spheres in the nanometer range is a recent story. In the past 5 years, it has become possible tomore » precisely control the particle size, surface area, pore size, chemical composition, and dispersity of carbon nanospheres. Toward this end, a number of synthetic strategies are emerging, such as hydrothermal carbonization of biomass-based resources, extended Stöber synthesis, and organic–organic self-assembly via different binding methods. In this feature article, we summarize recent routes for carbon nanospheres and briefly touch on their applications to shed light on the potential of this field. Throughout this article, a special emphasis is placed on the possible modulation of spherical structures at the nanoscale, and we wish to inspire many more designs and applications of carbon nanostructures in the near future.« less

A Flexible Analysis Tool for the Quantitative Acoustic Assessment of Infant Cry

PubMed Central

Reggiannini, Brian; Sheinkopf, Stephen J.; Silverman, Harvey F.; Li, Xiaoxue; Lester, Barry M.

2015-01-01

Purpose In this article, the authors describe and validate the performance of a modern acoustic analyzer specifically designed for infant cry analysis. Method Utilizing known algorithms, the authors developed a method to extract acoustic parameters describing infant cries from standard digital audio files. They used a frame rate of 25 ms with a frame advance of 12.5 ms. Cepstral-based acoustic analysis proceeded in 2 phases, computing frame-level data and then organizing and summarizing this information within cry utterances. Using signal detection methods, the authors evaluated the accuracy of the automated system to determine voicing and to detect fundamental frequency (F0) as compared to voiced segments and pitch periods manually coded from spectrogram displays. Results The system detected F0 with 88% to 95% accuracy, depending on tolerances set at 10 to 20 Hz. Receiver operating characteristic analyses demonstrated very high accuracy at detecting voicing characteristics in the cry samples. Conclusions This article describes an automated infant cry analyzer with high accuracy to detect important acoustic features of cry. A unique and important aspect of this work is the rigorous testing of the system’s accuracy as compared to ground-truth manual coding. The resulting system has implications for basic and applied research on infant cry development. PMID:23785178

Hypoglycemia in Patients with Diabetes and Renal Disease.

PubMed

Alsahli, Mazen; Gerich, John E

2015-05-13

This article summarizes our current knowledge of the epidemiology, pathogenesis, and morbidity of hypoglycemia in patients with diabetic kidney disease and reviews therapeutic limitations in this situation.

A review of catalytic microwave pyrolysis of lignocellulosic biomass for value-added fuel and chemicals.

PubMed

Morgan, Hervan Marion; Bu, Quan; Liang, Jianghui; Liu, Yujing; Mao, Hanping; Shi, Aiping; Lei, Hanwu; Ruan, Roger

2017-04-01

Lignocellulosic biomass is an abundant renewable resource and can be efficiently converted into bio-energy by a bio-refinery. From the various techniques available for biomass thermo-chemical conversion; microwave assisted pyrolysis (MAP) seems to be the very promising. The principles of microwave technology were reviewed and the parameters for the efficient production of bio-oil using microwave technology were summarized. Microwave technology by itself cannot efficiently produce high quality bio-oil products, catalysts are used to improve the reaction conditions and selectivity for valued products during MAP. The catalysts used to optimize MAP are revised in the development of this article. The origins for bio-oils that are phenol rich or hydrocarbon rich are reviewed and their experimental results were summarized. The kinetics of MAP is discussed briefly in the development of the article. Future prospects and scientific development of MAP are also considered in the development of this article. Copyright © 2017 Elsevier Ltd. All rights reserved.

Tips for a physician in getting the right job, part XIX: introduction to employment contracts.

PubMed

Harolds, Jay

2015-02-01

It is very helpful for physicians searching for a job to know a little about employment contracts. This article summarizes some important principles about contracts and some of their clauses. The article also emphasizes the importance of having the understandings regarding employment put in a formal written contract. This article may help the candidate avoid certain difficulties and may help in contract negotiations. However, this article is not a substitute for legal advice, and all physicians should consult a lawyer before signing an employment contract.

An overview of pharmaceutical cocrystals as intellectual property.

PubMed

Trask, Andrew V

2007-01-01

This review article focuses on the interaction among certain scientific, legal, and regulatory aspects of pharmaceutical crystal forms. The article offers an analysis of pharmaceutical cocrystals as patentable inventions by drawing upon recent scientific developments in the field. Several potential commercial advantages of pharmaceutical cocrystals are highlighted, and a number of recent court decisions involving salient issues are summarized. The article provides an outlook on how the developing field of cocrystallization may impact the pharmaceutical intellectual property landscape.

Radiomics of CT Features May Be Nonreproducible and Redundant: Influence of CT Acquisition Parameters.

PubMed

Berenguer, Roberto; Pastor-Juan, María Del Rosario; Canales-Vázquez, Jesús; Castro-García, Miguel; Villas, María Victoria; Legorburo, Francisco Mansilla; Sabater, Sebastià

2018-04-24

Purpose To identify the reproducible and nonredundant radiomics features (RFs) for computed tomography (CT). Materials and Methods Two phantoms were used to test RF reproducibility by using test-retest analysis, by changing the CT acquisition parameters (hereafter, intra-CT analysis), and by comparing five different scanners with the same CT parameters (hereafter, inter-CT analysis). Reproducible RFs were selected by using the concordance correlation coefficient (as a measure of the agreement between variables) and the coefficient of variation (defined as the ratio of the standard deviation to the mean). Redundant features were grouped by using hierarchical cluster analysis. Results A total of 177 RFs including intensity, shape, and texture features were evaluated. The test-retest analysis showed that 91% (161 of 177) of the RFs were reproducible according to concordance correlation coefficient. Reproducibility of intra-CT RFs, based on coefficient of variation, ranged from 89.3% (151 of 177) to 43.1% (76 of 177) where the pitch factor and the reconstruction kernel were modified, respectively. Reproducibility of inter-CT RFs, based on coefficient of variation, also showed large material differences, from 85.3% (151 of 177; wood) to only 15.8% (28 of 177; polyurethane). Ten clusters were identified after the hierarchical cluster analysis and one RF per cluster was chosen as representative. Conclusion Many RFs were redundant and nonreproducible. If all the CT parameters are fixed except field of view, tube voltage, and milliamperage, then the information provided by the analyzed RFs can be summarized in only 10 RFs (each representing a cluster) because of redundancy. © RSNA, 2018 Online supplemental material is available for this article.

Application of hot melt extrusion for poorly water-soluble drugs: limitations, advances and future prospects.

PubMed

Lu, Ming; Guo, Zhefei; Li, Yongcheng; Pang, Huishi; Lin, Ling; Liu, Xu; Pan, Xin; Wu, Chuanbin

2014-01-01

Hot melt extrusion (HME) is a powerful technology to enhance the solubility and bioavailability of poorly water-soluble drugs by producing amorphous solid dispersions. Although the number of articles and patents about HME increased dramatically in the past twenty years, there are very few commercial products by far. The three main obstacles limiting the commercial application of HME are summarized as thermal degradation of heat-sensitive drugs at high process temperature, recrystallization of amorphous drugs during storage and dissolving process, and difficulty to obtain products with reproducible physicochemical properties. Many efforts have been taken in recent years to understand the basic mechanism underlying these obstacles and then to overcome them. This article reviewed and summarized the limitations, recent advances, and future prospects of HME.

Reliability Prediction Analysis: Airborne System Results and Best Practices

NASA Astrophysics Data System (ADS)

Silva, Nuno; Lopes, Rui

2013-09-01

This article presents the results of several reliability prediction analysis for aerospace components, made by both methodologies, the 217F and the 217Plus. Supporting and complementary activities are described, as well as the differences concerning the results and the applications of both methodologies that are summarized in a set of lessons learned that are very useful for RAMS and Safety Prediction practitioners.The effort that is required for these activities is also an important point that is discussed, as is the end result and their interpretation/impact on the system design.The article concludes while positioning these activities and methodologies in an overall process for space and aeronautics equipment/components certification, and highlighting their advantages. Some good practices have also been summarized and some reuse rules have been laid down.

Polymer Physics of the Large-Scale Structure of Chromatin.

PubMed

Bianco, Simona; Chiariello, Andrea Maria; Annunziatella, Carlo; Esposito, Andrea; Nicodemi, Mario

2016-01-01

We summarize the picture emerging from recently proposed models of polymer physics describing the general features of chromatin large scale spatial architecture, as revealed by microscopy and Hi-C experiments.

Is my baby yellow?

PubMed

Cohain, Judy Slome

2006-01-01

In July 2004, The American Academy of Pediatrics (AAP) summarized the latest medical research regarding newborn jaundice and updated the current clinical guidelines. The AAP recommends that clinicians 1) promote breastfeeding and not routinely supplement newborns with water; 2) assess the risk of severe hyperbilirubinemia before discharge; 3) provide follow-up visits after discharge to assess jaundice; and 4) when indicated, treat newborns with phototherapy or exchange transfusion to prevent the development of severe hyperbilirubinemia and kernicterus. This article summarizes the new guidelines.

Beyond muscle destruction: a systematic review of rhabdomyolysis for clinical practice.

PubMed

Chavez, Luis O; Leon, Monica; Einav, Sharon; Varon, Joseph

2016-06-15

Rhabdomyolysis is a clinical syndrome that comprises destruction of skeletal muscle with outflow of intracellular muscle content into the bloodstream. There is a great heterogeneity in the literature regarding definition, epidemiology, and treatment. The aim of this systematic literature review was to summarize the current state of knowledge regarding the epidemiologic data, definition, and management of rhabdomyolysis. A systematic search was conducted using the keywords "rhabdomyolysis" and "crush syndrome" covering all articles from January 2006 to December 2015 in three databases (MEDLINE, SCOPUS, and ScienceDirect). The search was divided into two steps: first, all articles that included data regarding definition, pathophysiology, and diagnosis were identified, excluding only case reports; then articles of original research with humans that reported epidemiological data (e.g., risk factors, common etiologies, and mortality) or treatment of rhabdomyolysis were identified. Information was summarized and organized based on these topics. The search generated 5632 articles. After screening titles and abstracts, 164 articles were retrieved and read: 56 articles met the final inclusion criteria; 23 were reviews (narrative or systematic); 16 were original articles containing epidemiological data; and six contained treatment specifications for patients with rhabdomyolysis. Most studies defined rhabdomyolysis based on creatine kinase values five times above the upper limit of normal. Etiologies differ among the adult and pediatric populations and no randomized controlled trials have been done to compare intravenous fluid therapy alone versus intravenous fluid therapy with bicarbonate and/or mannitol.

Abstracts of State Legislated Hospital Cost-Containment Programs

PubMed Central

Esposito, Alfonso; Hupfer, Michael; Mason, Cynthia; Rogler, Diane

1982-01-01

This report summarizes State legislated efforts to control rising hospital costs and the status of these efforts in May 1982. The abstract for each of 17 State programs summarizes key legislative features and operating aspects. The States included in this report are: Arizona, California, Connecticut, Florida, Illinois, Maine, Maryland, Massachusetts, Minnesota, New Jersey, New York, Oregon, Rhode Island, Virginia, Washington, West Virginia, and Wisconsin. The abstracts focus on programs requiring the disclosure, review, or legislation of hospital rates and budgets. PMID:10309910

Recent Advances in Cyclodextrin-Based Light-Responsive Supramolecular Systems.

PubMed

Zhang, Xiaojin; Ma, Xin; Wang, Kang; Lin, Shijun; Zhu, Shitai; Dai, Yu; Xia, Fan

2018-06-01

Cyclodextrins (CDs), one of the host molecules in supramolecular chemistry, can host guest molecules to form inclusion complexes via non-covalent and reversible host-guest interactions. CD-based light-responsive supramolecular systems are typically constructed using CDs and guest molecules with light-responsive moieties, including azobenzene, arylazopyrazole, o-nitrobenzyl ester, pyrenylmethyl ester, coumarin, and anthracene. To date, numerous efforts have been reported on the topic of CD-based light-responsive supramolecular systems, but these have not yet been highlighted in a separated review. This review summarizes the efforts reported over the past ten years. The main text of this review is divided into five sections (vesicles, micelles, gels, capturers, and nanovalves) according to the formation of self-assemblies. This feature article aims to afford a comprehensive understanding of the light-responsive moieties used in the construction of CD-based light-responsive supramolecular systems and to provide a helpful guide for the further design of CD-based light-responsive supramolecular systems. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Assessing the role of relationship conflict in sexual dysfunction.

PubMed

Metz, Michael E; Epstein, Norman

2002-01-01

Relationship conflict has long been thought to cause, maintain, and influence the therapeutic outcome of sexual problems in the absence of a physical cause. The results of conflict can influence partners' relationship satisfaction, and relationship satisfaction can influence sexual satisfaction. General relationship deficiencies, such as unresolved conflict, undermine the mutual acceptance that is important to healthy sexual functioning. The purpose of this article is to summarize some of the basic empirical findings of studies of conflict patterns in relationships and their role in sex dysfunction and to suggest a model for assessing relationship conflict as a feature of sexual dysfunction. Results from several studies indicate that couples with sexual problems may have conflict-management issues and employ distinct conflict-resolution styles compared to satisfied couples. Dysfunctional conflict resolution may be a cause or result of some sexual problems, whereas constructive interaction concerning conflict can add to emotional and sexual intimacy in a couple's relationship. These patterns warrant systematic attention in assessment and intervention in sex therapy.

HFE gene in primary and secondary hepatic iron overload

PubMed Central

Sebastiani, Giada; Walker, Ann P

2007-01-01

Distinct from hereditary haemochromatosis, hepatic iron overload is a common finding in several chronic liver diseases. Many studies have investigated the prevalence, distribution and possible contributory role of excess hepatic iron in non-haemochromatotic chronic liver diseases. Indeed, some authors have proposed iron removal in liver diseases other than hereditary haemochromatosis. However, the pathogenesis of secondary iron overload remains unclear. The High Fe (HFE) gene has been implicated, but the reported data are controversial. In this article, we summarise current concepts regarding the cellular role of the HFE protein in iron homeostasis. We review the current status of the literature regarding the prevalence, hepatic distribution and possible therapeutic implications of iron overload in chronic hepatitis C, hepatitis B, alcoholic and non-alcoholic fatty liver diseases and porphyria cutanea tarda. We discuss the evidence regarding the role of HFE gene mutations in these liver diseases. Finally, we summarize the common and specific features of iron overload in liver diseases other than haemochromatosis. PMID:17729389

[Proteomics and its application to determine mechanism of action of traditional Chinese medicine].

PubMed

Xin, Ping; Kuang, Hai-Xue; Li, Xiao-Liang; Wang, Yu; Zhang, Ben-Mei; Bu, He; Wang, Zhi-Bin; Meng, Yong-Hai; Wang, Yan-Hong; Wang, Qiu-Hong

2018-03-01

There is no doubt that the traditional Chinese medicine(TCM) is effective, practical and scientific after it was used for thousands of years. However, the mechanisms of action of many TCM are still unclear because of their multi-component, multi-target and multi-level features, which hinder the modernization and internationalization of the TCM. Proteomics is to analyze the composition and activity of intracellular proteins which are changing dynamically from a holistic perspective. It is consistent with the holistic and dynamic views of the TCM and brings about the hope of clarifying the mechanism of action of the TCM. In recent years, great progress has been made in the application of proteomics to determine the mechanism of the TCM. This article introduced the core technologies of proteomics and systematically summarized the applications of proteomics in the study of the mechanism of the Chinese medicinal formulae, single Chinese medicine and monomeric compounds from the TCM to provide innovative ideas and methods for reference. Copyright© by the Chinese Pharmaceutical Association.

Transepithelial and endothelial transport of poly (amidoamine) dendrimers.

PubMed

Kitchens, Kelly M; El-Sayed, Mohamed E H; Ghandehari, Hamidreza

2005-12-14

This article summarizes our efforts to evaluate the potential of poly (amidoamine) (PAMAM) dendrimers as carriers for oral drug delivery. Specifically, the permeability of a series of cationic PAMAM-NH2 (G0-G4) dendrimers across Caco-2 cell monolayers was evaluated as a function of dendrimer generation, concentration, and incubation time. The influence of dendrimer surface charge on the integrity, paracellular permeability, and viability of Caco-2 cell monolayers was monitored by measuring the transepithelial electrical resistance (TEER), 14C-mannitol permeability, and leakage of lactate dehydrogenase (LDH) enzyme, respectively. Microvascular extravasation of PAMAM-NH2 dendrimers in relation to their size, molecular weight, and molecular geometry is also discussed. Results of these studies show that transepithelial transport and microvascular extravasation of PAMAM dendrimers are dependent on their structural features including molecular size, molecular geometry, and surface chemistry. These results suggest that by optimizing the size and surface charge of PAMAM dendrimers, it is possible to develop oral delivery systems based on these carriers for targeted drug delivery.

Recent progress in advanced optical materials based on gadolinium aluminate garnet (Gd3Al5O12)

PubMed Central

Li, Ji-Guang; Sakka, Yoshio

2015-01-01

This review article summarizes the recent achievements in stabilization of the metastable lattice of gadolinium aluminate garnet (Gd3Al5O12, GAG) and the related developments of advanced optical materials, including down-conversion phosphors, up-conversion phosphors, transparent ceramics, and single crystals. Whenever possible, the materials are compared with their better known YAG and LuAG counterparts to demonstrate the merits of the GAG host. It is shown that novel emission features and significantly improved luminescence can be attained for a number of phosphor systems with the more covalent GAG lattice and the efficient energy transfer from Gd3+ to the activator. Ce3+ doped GAG-based single crystals and transparent ceramics are also shown to simultaneously possess the advantages of high theoretical density, fast scintillation decay, and high light yields, and hold great potential as scintillators for a wide range of applications. The unresolved issues are also pointed out. PMID:27877750

Perivascular epithelioid cell neoplasm (PEComa) of the uterus: A systematic review.

PubMed

Musella, Angela; De Felice, Francesca; Kyriacou, A Kyriacos; Barletta, Francesco; Di Matteo, Filippo Maria; Marchetti, Claudia; Izzo, Luciano; Monti, Marco; Benedetti Panici, Pierluigi; Redler, Adriano; D'Andrea, Vito

2015-07-01

Perivascular epithelioid cell neoplasm (PEComa) is a rare mesenchymal tumor. Gynecological PEComas account for just over one-fourth of the overall PEComa cases reported in the literature. Surgery is the most recommended primary treatment while adjuvant therapy is generally reserved for high-risk cases. However, the best management of this neoplasia has not been well established, primarily because of the paucity of cases described to date. The aim of this systematic review is to summarize what is known thus far regarding the etiopathogenesis, clinical and pathologic features of PEComas, focusing also on the most valid treatment options for uterine cases. Pubmed articles on PEComas published in various journals over the past 70 years were analyzed. Although the optimal treatment of gynecological PEComas is controversial, surgical resection remains the cornerstone. The use of adjuvant treatment is warranted in high risk patients to increase disease control. A multidisciplinary approach should be key in treatment decision-making regarding gynecological PEComas. Copyright © 2015 IJS Publishing Group Limited. Published by Elsevier Ltd. All rights reserved.

The Medicare Access And CHIP Reauthorization Act And The Corporate Transformation Of American Medicine.

PubMed

Casalino, Lawrence P

2017-05-01

The Medicare Access and CHIP Reauthorization Act of 2015 (MACRA) may accelerate the movement of physicians into corporate employment by hospitals and, to a lesser extent, by health insurers and other corporations. This article briefly summarizes the demographics of US physician practice, the potential advantages and disadvantages of physician employment by large corporations, and the evidence to date on the performance of large versus small physician practices and hospital-employed versus independent physicians. It describes the features of MACRA likely to lead physicians to seek corporate employment and the steps the Centers for Medicare and Medicaid Services has taken through MACRA to aid small independent physician practices. I conclude that MACRA's net effect is likely to be accelerated corporate employment of physicians and that there is an urgent need for more evidence on the impact of different types of provider organization on the quality and cost of care, and on patient, physician, and staff experience. Project HOPE—The People-to-People Health Foundation, Inc.

Demonstration and Pantomime in the Evolution of Teaching.

PubMed

Gärdenfors, Peter

2017-01-01

Donald proposes that early Homo evolved mimesis as a new form of cognition. This article investigates the mimesis hypothesis in relation to the evolution of teaching. The fundamental capacities that distinguish hominin teaching from that of other animals are demonstration and pantomime. A conceptual analysis of the instructional and communicative functions of demonstration and pantomime is presented. Archaeological evidence that demonstration was used for transmitting the Oldowan technology is summarized. It is argued that pantomime develops out of demonstration so that the primary objective of pantomime is that the onlooker learns the motoric patterns shown in the pantomime. The communicative use of pantomime is judged to be secondary. This use of pantomime is also contrasted with other forms of gestures. A key feature of the analysis is that the meaning of a pantomime is characterized by the force patterns of the movements. These force patterns form the core of a model of the cognitive mechanism behind pantomime. Finally, the role of pantomime in the evolution of language is also discussed.

Demonstration and Pantomime in the Evolution of Teaching

PubMed Central

Gärdenfors, Peter

2017-01-01

Donald proposes that early Homo evolved mimesis as a new form of cognition. This article investigates the mimesis hypothesis in relation to the evolution of teaching. The fundamental capacities that distinguish hominin teaching from that of other animals are demonstration and pantomime. A conceptual analysis of the instructional and communicative functions of demonstration and pantomime is presented. Archaeological evidence that demonstration was used for transmitting the Oldowan technology is summarized. It is argued that pantomime develops out of demonstration so that the primary objective of pantomime is that the onlooker learns the motoric patterns shown in the pantomime. The communicative use of pantomime is judged to be secondary. This use of pantomime is also contrasted with other forms of gestures. A key feature of the analysis is that the meaning of a pantomime is characterized by the force patterns of the movements. These force patterns form the core of a model of the cognitive mechanism behind pantomime. Finally, the role of pantomime in the evolution of language is also discussed. PMID:28382011

Focus group interview: an underutilized research technique for improving theory and practice in health education.

PubMed

Basch, C E

1987-01-01

The purpose of this article is to increase awareness about and stimulate interest in using focus group interviews, a qualitative research technique, to advance the state-of-the-art of education and learning about health. After a brief discussion of small group process in health education, features of focus group interviews are presented, and a theoretical framework for planning a focus group study is summarized. Then, literature describing traditional and health-related applications of focus group interviews is reviewed and a synthesis of methodological limitations and advantages of this technique is presented. Implications are discussed regarding: need for more inductive qualitative research in health education; utility of focus group interviews for research and for formative and summative evaluation of health education programs; applicability of marketing research to understanding and influencing consumer behavior, despite notable distinctions between educational initiatives and marketing; and need for professional preparation faculty to consider increasing emphasis on qualitative research methods.

Review article: Fabrication of nanofluidic devices

PubMed Central

Duan, Chuanhua; Wang, Wei; Xie, Quan

2013-01-01

Thanks to its unique features at the nanoscale, nanofluidics, the study and application of fluid flow in nanochannels/nanopores with at least one characteristic size smaller than 100 nm, has enabled the occurrence of many interesting transport phenomena and has shown great potential in both bio- and energy-related fields. The unprecedented growth of this research field is apparently attributed to the rapid development of micro/nanofabrication techniques. In this review, we summarize recent activities and achievements of nanofabrication for nanofluidic devices, especially those reported in the past four years. Three major nanofabrication strategies, including nanolithography, microelectromechanical system based techniques, and methods using various nanomaterials, are introduced with specific fabrication approaches. Other unconventional fabrication attempts which utilize special polymer properties, various microfabrication failure mechanisms, and macro/microscale machining techniques are also presented. Based on these fabrication techniques, an inclusive guideline for materials and processes selection in the preparation of nanofluidic devices is provided. Finally, technical challenges along with possible opportunities in the present nanofabrication for nanofluidic study are discussed. PMID:23573176

Rejuvenation of the Aging Arm: Multimodal Combination Therapy for Optimal Results.

PubMed

Wu, Douglas C; Green, Jeremy B

2016-05-01

The aging arm is characterized by increased dyspigmentation, a proliferation of ectactic blood vessels, excessive adiposity, excessive skin laxity, and actinic keratosis. A variety of laser, energy, and surgical techniques can be used to improve these features. The objective of this article is to describe the treatment modalities that have proven efficacious in rejuvenating the aging arm and combination therapies that have the potential to optimize patient outcomes while maintaining safety and tolerability. A Medline search was performed on nonsurgical aesthetic combination treatments because it relates to arm rejuvenation, and results are summarized. Practical applications for these combination treatments are also discussed. Although there is significant evidence supporting the effective use of nonsurgical treatments for arm rejuvenation, little in the literature was found on the safety and efficacy of combining such procedures and devices. However, in the authors' clinical experience, combining arm rejuvenation techniques can be done safely and often result in optimal outcomes. Arm rejuvenation can be safely and effectively achieved with combination nonsurgical aesthetic treatments.

Tension-Type Headache - The Normal and Most Prevalent Headache.

PubMed

Jensen, Rigmor Højland

2018-02-01

Tension-type headache (TTH) is the most prevalent form of primary headache in the general population but paradoxically the least studied headache. In this article, the epidemiology and diagnostic challenges of TTH are presented and discussed. The typical features and differential diagnosis of TTH are highlighted and the situations more likely to raise doubts are discussed. A structured approach to the patient and a better comprehension of the very frequent coexistence of migraine and medication overuse headache in the clinical population are emphasized. According to the IHS classification, several diagnoses should be applied but still some clinicians prefer to apply a single combined diagnosis in the severely affected patients, namely chronic migraine. Such uneven practice may complicate the diagnostic comparability and the entire management of TTH. The present treatment strategies for TTH are summarized and hopefully an increased awareness of TTH can translate into better quality of care and a more specific diagnosis and treatment for the numerous TTH sufferers. © 2017 American Headache Society.

Components and Quality Measures of DIME (Devitalized Tissue, Infection/Inflammation, Moisture Balance, and Edge Preparation) in Wound Care

PubMed Central

Snyder, Robert J.; Fife, Caroline; Moore, Zena

2016-01-01

ABSTRACT OBJECTIVES: To discuss how patient considerations and the initial wound environment can affect wound treatment and summarize the way in which the initial US Wound Registry measures capture aspects of the DIME (Debridement/devitalized tissue, Infection or inflammation, Moisture balance, and wound Edge preparation/wound depth) principles. DISCUSSION: The treatment of chronic wounds often involves extended hospital stays and long-term outpatient follow-up visits with costly advanced therapeutic interventions. As complex care is required for chronic wounds, treatment guidelines such as DIME have evolved to include consideration of patient-centered concerns and etiology, as well as features of wound bed preparation. The US healthcare system is in the midst of transitioning to a quality-based system. However, as wound care is not yet a recognized specialty, it is poorly represented in the current approved quality-based measures. CONCLUSION: This article helps to identify the practice guidelines that are not currently represented by quality metrics. PMID:27089149

Persistent neural activity in head direction cells

NASA Technical Reports Server (NTRS)

Taube, Jeffrey S.; Bassett, Joshua P.; Oman, C. M. (Principal Investigator)

2003-01-01

Many neurons throughout the rat limbic system discharge in relation to the animal's directional heading with respect to its environment. These so-called head direction (HD) cells exhibit characteristics of persistent neural activity. This article summarizes where HD cells are found, their major properties, and some of the important experiments that have been conducted to elucidate how this signal is generated. The number of HD and angular head velocity cells was estimated for several brain areas involved in the generation of the HD signal, including the postsubiculum, anterior dorsal thalamus, lateral mammillary nuclei and dorsal tegmental nucleus. The HD cell signal has many features in common with what is known about how neural integration is accomplished in the oculomotor system. The nature of the HD cell signal makes it an attractive candidate for using neural network models to elucidate the signal's underlying mechanisms. The conditions that any network model must satisfy in order to accurately represent how the nervous system generates this signal are highlighted and areas where key information is missing are discussed.

Differential diagnosis of the scalp hair folliculitis.

PubMed

Lugović-Mihić, Liborija; Barisić, Freja; Bulat, Vedrana; Buljan, Marija; Situm, Mirna; Bradić, Lada; Mihić, Josip

2011-09-01

Scalp hair folliculitis is a relatively common condition in dermatological practice and a major diagnostic and therapeutic challenge due to the lack of exact guidelines. Generally, inflammatory diseases of the pilosebaceous follicle of the scalp most often manifest as folliculitis. There are numerous infective agents that may cause folliculitis, including bacteria, viruses and fungi, as well as many noninfective causes. Several noninfectious diseases may present as scalp hair folliculitis, such as folliculitis decalvans capillitii, perifolliculitis capitis abscendens et suffodiens, erosive pustular dermatitis, lichen planopilaris, eosinophilic pustular folliculitis, etc. The classification of folliculitis is both confusing and controversial. There are many different forms of folliculitis and several classifications. According to the considerable variability of histologic findings, there are three groups of folliculitis: infectious folliculitis, noninfectious folliculitis and perifolliculitis. The diagnosis of folliculitis occasionally requires histologic confirmation and cannot be based solely on clinical appearance of scalp lesions. This article summarizes prominent variants of inflammatory diseases of the scalp hair follicle with differential diagnosis and appertaining histological features.

[How free is free will? Neuro-scientific and philosophical aspects of motivation and decision-making].

PubMed

Hinterhuber, Hartmann

2012-01-01

The question concerning the postulated freedom of will continues to occupy the neuro-sciences, psychiatry, law and neuro-philosophy. Do current research results really show that freedom and responsibility were only illusions, since previously supposed free decisions were only accompanying features of long held neuronal activations? Did Julien de La Mettrie have a great vision, when, already in the Eighteenth Century, he expected a "monsieur Machine"?This article attempts to summarize and evaluate findings that are currently available. The autonomy of human action is not only founded in a subjectively perceived act of will but far more in the ability of the human being to act according to an inner drive which is steered consciously and rationally. The autonomy of human action is not only restricted to the perceived ego, but comprises body and soul, brain and spirit and consequently the whole human being with all their characteristics, values and aims. Modern science thereby supports the old philosophical theory of a conditional freedom of will.

Unevenly distributed: a systematic review of the health literature about socioeconomic inequalities in adult obesity in the United Kingdom

PubMed Central

2012-01-01

Background There is a growing literature documenting socioeconomic inequalities in obesity risk among adults in the UK, with poorer groups suffering higher risk. Methods In this systematic review, we summarize and appraise the extant peer-reviewed literature about socioeconomic inequalities in adult obesity risk in the UK published between 1980 and 2010. Only studies featuring empirical assessments of relations between socioeconomic indicators and measures of obesity among adults in the UK were included. Results A total of 35 articles met inclusion criteria, and were reviewed here. Conclusion Socioeconomic indicators of low socioeconomic position (SEP), including occupational social class of the head-of-household at birth and during childhood, earlier adulthood occupational social class, contemporaneous occupational social class, educational attainment, and area-level deprivation were generally inversely associated with adult obesity risk in the UK. Measures of SEP were more predictive of obesity among women than among men. We outline important methodological limitations to the literature and recommend avenues for future research. PMID:22230643

Science and pseudoscience in the development of eye movement desensitization and reprocessing: implications for clinical psychology.

PubMed

Herbert, J D; Lilienfeld, S O; Lohr, J M; Montgomery, R W; O'Donohue, W T; Rosen, G M; Tolin, D F

2000-11-01

The enormous popularity recently achieved by Eye Movement Desensitization and Reprocessing (EMDR) as a treatment for anxiety disorders appears to have greatly outstripped the evidence for its efficacy from controlled research studies. The disparity raises disturbing questions concerning EMDR's aggressive commercial promotion and its rapid acceptance among practitioners. In this article, we: (1) summarize the evidence concerning EMDR's efficacy; (2) describe the dissemination and promotion of EMDR; (3) delineate the features of pseudoscience and explicate their relevance to EMDR; (4) describe the pseudoscientific marketing practices used to promote EMDR; (5) analyze factors contributing to the acceptance of EMDR by professional psychologists; and (6) discuss practical considerations for professional psychologists regarding the adoption of EMDR into professional practice. We argue that EMDR provides an excellent vehicle for illustrating the differences between scientific and pseudoscientific therapeutic techniques. Such distinctions are of critical importance for clinical psychologists who intend to base their practice on the best available research.

Recent progress in advanced optical materials based on gadolinium aluminate garnet (Gd3Al5O12)

NASA Astrophysics Data System (ADS)

Li, Ji-Guang; Sakka, Yoshio

2015-02-01

This review article summarizes the recent achievements in stabilization of the metastable lattice of gadolinium aluminate garnet (Gd3Al5O12, GAG) and the related developments of advanced optical materials, including down-conversion phosphors, up-conversion phosphors, transparent ceramics, and single crystals. Whenever possible, the materials are compared with their better known YAG and LuAG counterparts to demonstrate the merits of the GAG host. It is shown that novel emission features and significantly improved luminescence can be attained for a number of phosphor systems with the more covalent GAG lattice and the efficient energy transfer from Gd3+ to the activator. Ce3+ doped GAG-based single crystals and transparent ceramics are also shown to simultaneously possess the advantages of high theoretical density, fast scintillation decay, and high light yields, and hold great potential as scintillators for a wide range of applications. The unresolved issues are also pointed out.

Exercise Testing, Training, and Beta-Adrenergic Blockade.

ERIC Educational Resources Information Center

Wilmore, Jack H.

1988-01-01

This article summarizes the current knowledge on the effects of beta-adrenergic blocking drugs, used widely for treatment of cardiovascular diseases, on exercise performance, training benefits, and exercise prescription. (IAH)

Fred Hoyle's birth centennial

NASA Astrophysics Data System (ADS)

Mitton, Simon

2015-12-01

Simon Mitton summarizes the RAS Specialist Discussion Meeting that examined from a historical perspective Hoyle's remarkable career and the impact of his science, in the first of two articles on his scientific legacy.

Hypoglycemia in Patients with Diabetes and Renal Disease

PubMed Central

Alsahli, Mazen; Gerich, John E.

2015-01-01

This article summarizes our current knowledge of the epidemiology, pathogenesis, and morbidity of hypoglycemia in patients with diabetic kidney disease and reviews therapeutic limitations in this situation. PMID:26239457

Seismic performance of low-rise wood buildings

Treesearch

Lawrence A. Soltis; Robert H. Falk

1992-01-01

This article updates a previous literature review paper on the performance of woodframe buildings during earthquakes and summarizes recent research related to understanding seismic behavior of low-rise wood buildings.

Criminal acts against civil aviation

DOT National Transportation Integrated Search

2001-01-01

Criminal Acts Against Civil Aviation reports on incidents that have taken place against civil aviation aircraft and interests worldwide. Incidents that are recorded are summarized in regional geographic overviews. In addition, one or more feature art...

DISCOVER-AQ

Atmospheric Science Data Center

2017-01-31

... Relevant Documents:  DISCOVER-AQ - Airborne Science Data for Atmospheric Composition DISCOVER-AQ - NASA Earth ... DISCOVER-AQ - Mission Highlight Featured Articles : Articles featuring DISCOVER-AQ data products SCAR-B ...

An update of the federal drinking water regs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pontius, F.W.

1995-02-01

Previous reviews have summarized the regulations promulgated for volatile organic chemicals (VOCs), fluoride, surface water treatment, total coliform bacteria, lead and copper, and Phase 2 and Phase 5 synthetic organic contaminants (SOCs) and inorganic contaminants (IOCs). Current developments related to these rules and anticipated new rules are reviewed in this article. Current numerical drinking water standards and best available technology (BAT) are summarized. The status of all current, proposed, and anticipated regulations is also summarized. Dates for anticipated agency actions are based on the US Environmental Protection Agency's (USEPA's) published regulatory agenda and on information released by the agency throughmore » December 1994; these dates can change as the agency reconsiders its regulatory policies.« less

Dental management of pediatric patients affected by pulmonary atresia with ventricular septal defect: A scoping review.

PubMed

Garrocho-Rangel, A; Echavarría-García, A-C; Rosales-Bérber, M-A; Flores-Velázquez, J; Pozos-Guillén, A

2017-07-01

Congenital Heart Diseases (CHD) involves a wide range of pathological conditions, such as Pulmonary Atresia with Ventricle Septal Defect (PA/VSD). This disorder leads to the systemic circulation of oxygen-poor blood (cyanosis), with associated features and consequences in the oral cavity. Using scoping review methodology for screening and article selection, the primary objectives of this paper were as follows: first, to pose a research question; second, to identify relevant studies in order to answer the research question; third, to select and retrieve the studies; fourth, to chart the critical data, and finally, to collate, summarize, and report the results from the most important articles on the dental management of children affected with PA/VSD. Relevant articles (Randomized Controlled Trials [RCT], reviews, observational studies, and clinical case reports) published over a 10-year period were identified and retrieved from four Internet databases: PubMed; Embase/Ovid; Cochrane Library, and Google Scholar. By title and abstract screening and after removing duplicates, 24 articles were finally included in the present scoping review. According to the extracted data, the following are the most important clinical issues to be considered when treating children with PA/VSD in the dental setting: prevalence of dental caries; prevention of dental disease (oral hygiene and diet); bacteremia and infective endocarditis risk, and child behavior control and treatment under general anesthesia. Pediatric Dentists should bear in mind that early diagnosis and treatment, together a long-term follow-up of children with PA/VSD, continue to be the best approaches for achieving enhanced patient psychological well-being and, in consequence, their good quality of life.

New England Wind Forum: A Wind Powering America Project, Volume 1, Issue 4 -- May 2008 (Newsletter)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Grace, R. C.; Gifford, J.

2008-05-01

The New England Wind Forum electronic newsletter summarizes the latest news in wind energy development activity, markets, education, and policy in the New England region. It also features an interview with a key figure influencing New England's wind energy development. Volume 1, Issue 4 features an interview with Brian Fairbank, president and CEO of Jiminy Peak Mountain Resort.

Concept design and alternate arrangements of orbiter mid-deck habitability features

NASA Technical Reports Server (NTRS)

Church, R. A.; Ciciora, J. A.; Porter, K. L.; Stevenson, G. E.

1976-01-01

The evaluations and recommendations for habitability features in the space shuttle orbiter mid-deck are summarized. The orbiter mission plans, the mid-deck dimensions and baseline arrangements along with crew compliments and typical activities were defined. Female and male anthropometric data based on zero-g operations were also defined. Evaluations of baseline and alternate feasible concepts provided several recommendations which are discussed.

A Method for Populating the Knowledge Base of APTAS, a Domain-Oriented Application Composition System

DTIC Science & Technology

1993-12-01

proposed a domain analysis approach called Feature-Oriented Domain Analysis ( FODA ). The approach identifies prominent features (similarities) and...characteristics of software systems in the domain. Unlike the other domain analysis approaches we have summarized, the re- searchers described FODA in...Domain Analysis ( FODA ) Feasibility Study. Technical Report, Software Engineering Institute, Carnegie Mellon University, Novem- ber 1990. 19. Lee, Kenneth

The 1992 Research/Technology report

NASA Technical Reports Server (NTRS)

1992-01-01

The 1992 Research & Technology report is organized so that a broad cross section of the community can readily use it. A short introductory paragraph begins each article and will prove to be an invaluable reference tool for the layperson. The approximately 200 articles summarize the progress made during the year in various technical areas and portray the technical and administrative support associated with Lewis technology programs.

Cross-Cultural Perspectives on the Classification of Children with Disabilities: Part II. Implementing Classification Systems in Schools

ERIC Educational Resources Information Center

McLaughlin, Margaret J.; Dyson, Alan; Nagle, Katherine; Thurlow, Martha; Rouse, Martyn; Hardman, Michael; Norwich, Brahm; Burke, Phillip J.; Perlin, Michael

2006-01-01

This article is the second in a 2-part synthesis of an international comparative seminar on the classification of children with disabilities. In this article, the authors discuss classification frameworks used in identifying children for the purpose of providing special education and related services. The authors summarize 7 papers that addressed…

A Critical Review of Research on Strategies in Learning Chinese as Both a Second and Foreign Language

ERIC Educational Resources Information Center

Jiang, Xiaoli; Cohen, Andrew D.

2012-01-01

This article critically reviews strategy research on learning Chinese both as a second and foreign language. Through a careful examination of major data bases in both the Chinese and English languages, the article summarizes research in the field and the principal research methods used in the studies reviewed. Moreover, key limitations in research…

Electronic health records in an occupational health setting-Part II. Global deployment.

PubMed

Bey, Jean M; de Magalhães, Josiane S; Bojórquez, Lorena; Lin, Karen

2013-03-01

Electronic medical record systems are being used by more multi-national corporations. This article describes one corporation's considerations and process in successfully deploying a global electronic medical record system to international facilities in Brazil, Mexico, Singapore, and Taiwan. This article summarizes feedback from the experiences of occupational health nurse superusers in these countries. Copyright 2013, SLACK Incorporated.

The Legal Side of Campus Threat Assessment and Management: What Student Counselors Need to Know

ERIC Educational Resources Information Center

Nolan, Jeffrey J.; Moncure, Thomas M., Jr.

2012-01-01

This article identifies what student mental health professionals need to know about legal issues of relevance to threat assessment and management. The article summarizes the common law duties and the common law and statutory standards of care that are likely to apply to the work of college and university threat assessment and management teams. The…

Research and technology

NASA Technical Reports Server (NTRS)

1987-01-01

The NASA Lewis Research Center's research and technology accomplishments for fiscal year 1987 are summarized. It comprises approximately 100 short articles submitted by staff members of the technical directorates and is organized into four sections: aeronautics, aerospace technology (which includes space communications), space station systems, and computational support. A table of contents by subject was developed to assist the reader in finding articles of special interest.

What's at Stake in the Lives of People with Intellectual Disability? Part I: The Power of Naming, Defining, Diagnosing, Classifying, and Planning Supports

ERIC Educational Resources Information Center

Schalock, Robert L.; Luckasson, Ruth

2013-01-01

This article focuses on the power of naming, defining, diagnosing, classifying, and planning supports for people with intellectual disability. The article summarizes current thinking regarding these five functions, states the essential question addressed by the respective function, and provides an overview of the high stakes involved for people…

Education Abroad in China: Literature Review of Study Abroad Program Types, Outcomes and Benefits

ERIC Educational Resources Information Center

Dixon, Brett

2013-01-01

While there has been an increase in students studying abroad in China, this increase has not been seen in the respective number of articles published in scholarly journals on education abroad in China. This paper summarizes articles from journals on the types of education abroad programs in China, organized by topic, and by the outcomes and…

Child Care and the New Economy: Part 2--The Future of the Early Childhood Profession

ERIC Educational Resources Information Center

Neugebauer, Roger

2009-01-01

In the September/October issue the author analyzed trends in business and society and identified three pillars of the new economy. After that article was published, readers were asked to share their views on what these changes mean for the world of early childhood. In this article, the author summarizes respondent's views. [For Part 1, see…

The current status of research on the structure of evaluative space

PubMed Central

Norris, Catherine J.; Gollan, Jackie; Berntson, Gary G.; Cacioppo, John T.

2009-01-01

The structure of evaluative space shapes emotional life. Although behavior may be constrained to a single bipolar dimension, for example as defined by the opposing movements of approach and withdrawal, the mechanisms underlying the affect system must be capable of an astonishing range of emotional experience and expression. The model of evaluative space (ESM; J. T. Cacioppo, W. L. Gardner, & G. G. Berntson, 1997, 1999) proposes that behavioral predispositions are the ultimate output of the affect system, which is defined by operating characteristics that differ both for positivity and negativity, as well as across levels of the nervous system. In this article, we outline the current status of theory and research on the structure of evaluative space. First, we summarize the basic tenets of the model, as well as recent research supporting these ideas and counterarguments that have been raised by other theorists. To address these counterarguments, we discuss the postulates of affective oscillation and calibration, two mechanistic features of the affect system proposed to underlie the durability and adaptability of affect. We summarize empirical support for the functional consequences of the principles of affective oscillation and calibration, with a focus on how oscillation and the “stickiness” of affect can lead to the emergence of ambivalence, whereas affective calibration and the flexibility of the affect system produce asymmetries in affective processing (e.g., the negativity bias). Finally, we consider the clinical implications of disorder in the structure of evaluative space for the comprehension and treatment of depression and anxiety. PMID:20346389

Nature: A Box of Physical, Chemical, and Biological Tricks

NASA Astrophysics Data System (ADS)

Heinhorst, Sabine; Cannon, Gordon C.

2008-03-01

This article summarizes scientific breakthroughs, originally reported in the journal Nature, in the development of wet-dry adhesives, pain-selective anesthetics, enantioselective cyclizations and mechanical stress-induced chemical reactions.

This Month in AJP.

PubMed

2018-05-17

The following highlights summarize research articles that are published in the current issue of The American Journal of Pathology. Copyright © 2018 American Society for Investigative Pathology. Published by Elsevier Inc. All rights reserved.

This Month in AJP.

PubMed

2018-06-18

The following highlights summarize research articles that are published in the current issue of The American Journal of Pathology. Copyright © 2018 American Society for Investigative Pathology. Published by Elsevier Inc. All rights reserved.

This Month in AJP.

PubMed

2018-06-01

The following highlights summarize research articles that are published in the current issue of The American Journal of Pathology. Copyright © 2018 American Society for Investigative Pathology. Published by Elsevier Inc. All rights reserved.

This Month in AJP.

PubMed

2018-05-01

The following highlights summarize research articles that are published in the current issue of The American Journal of Pathology. Copyright © 2018 American Society for Investigative Pathology. Published by Elsevier Inc. All rights reserved.

Recent Advances in Endoscopy.

PubMed

Wallace, Michael B; Wang, Kenneth K; Adler, Douglas G; Rastogi, Amit

2017-08-01

In this narrative review, invited by the Editors of Gastroenterology, we summarize recent advances in the field of gastrointestinal endoscopy. We have chosen articles published primarily in the past 2-3 years. Although a thorough literature review was performed for each topic, the nature of the article is subjective and systematic and is based on the authors' experience and expertise regarding articles we believed were most likely to be of high clinical and scientific importance. Copyright © 2017 AGA Institute. Published by Elsevier Inc. All rights reserved.

Hybrid Wing Body Multi-Bay Test Article Analysis and Assembly Final Report

NASA Technical Reports Server (NTRS)

Velicki, Alexander; Hoffman, Krishna; Linton, Kim A.; Baraja, Jaime; Wu, Hsi-Yung T.; Thrash, Patrick

2017-01-01

This report summarizes work performed by The Boeing Company, through its Boeing Research & Technology organization located in Huntington Beach, California, under the Environmentally Responsible Aviation (ERA) project. The report documents work performed to structurally analyze and assemble a large-scale Multi-bay Box (MBB) Test Article capable of withstanding bending and internal pressure loadings representative of a Hybrid Wing Body (HWB) aircraft. The work included fabrication of tooling elements for use in the fabrication and assembly of the test article.

Applications of stable isotope analysis in mammalian ecology.

PubMed

Walter, W David; Kurle, Carolyn M; Hopkins, John B

2014-01-01

In this editorial, we provide a brief introduction and summarize the 10 research articles included in this Special Issue on Applications of stable isotope analysis in mammalian ecology. The first three articles report correction and discrimination factors that can be used to more accurately estimate the diets of extinct and extant mammals using stable isotope analysis. The remaining seven applied research articles use stable isotope analysis to address a variety of wildlife conservation and management questions from the oceans to the mountains.

Comparsion analysis of data mining models applied to clinical research in traditional Chinese medicine.

PubMed

Zhao, Yufeng; Xie, Qi; He, Liyun; Liu, Baoyan; Li, Kun; Zhang, Xiang; Bai, Wenjing; Luo, Lin; Jing, Xianghong; Huo, Ruili

2014-10-01

To help researchers selecting appropriate data mining models to provide better evidence for the clinical practice of Traditional Chinese Medicine (TCM) diagnosis and therapy. Clinical issues based on data mining models were comprehensively summarized from four significant elements of the clinical studies: symptoms, symptom patterns, herbs, and efficacy. Existing problems were further generalized to determine the relevant factors of the performance of data mining models, e.g. data type, samples, parameters, variable labels. Combining these relevant factors, the TCM clinical data features were compared with regards to statistical characters and informatics properties. Data models were compared simultaneously from the view of applied conditions and suitable scopes. The main application problems were the inconsistent data type and the small samples for the used data mining models, which caused the inappropriate results, even the mistake results. These features, i.e. advantages, disadvantages, satisfied data types, tasks of data mining, and the TCM issues, were summarized and compared. By aiming at the special features of different data mining models, the clinical doctors could select the suitable data mining models to resolve the TCM problem.

Feature selection for examining behavior by pathology laboratories.

PubMed

Hawkins, S; Williams, G; Baxter, R

2001-08-01

Australia has a universal health insurance scheme called Medicare, which is managed by Australia's Health Insurance Commission. Medicare payments for pathology services generate voluminous transaction data on patients, doctors and pathology laboratories. The Health Insurance Commission (HIC) currently uses predictive models to monitor compliance with regulatory requirements. The HIC commissioned a project to investigate the generation of new features from the data. Feature generation has not appeared as an important step in the knowledge discovery in databases (KDD) literature. New interesting features for use in predictive modeling are generated. These features were summarized, visualized and used as inputs for clustering and outlier detection methods. Data organization and data transformation methods are described for the efficient access and manipulation of these new features.

Early Warnings for Local Labor Markets

ERIC Educational Resources Information Center

Matland, Marc A.

1976-01-01

This articles summarizes the National Planning Association's (NPA) experience in its initial efforts to develop an early warning system to anticipate job openings generated in local communities by large Federal procurement contracts. (WL)

Interferometric Synthetic Aperture radar studies of Alaska volcanoes

USGS Publications Warehouse

Lu, Zhong; Wicks, Charles W.; Dzurisin, Daniel; Power, John A.; Thatcher, Wayne R.; Masterlark, Timothy

2003-01-01

In this article, we summarize our recent InSAR studies of 13 Alaska volcanoes, including New Trident, Okmok, Akutan, Kiska, Augustine, Westdahl, Peulik, Makushin, Seguam, Shishaldin, Pavlof, Cleveland, and Korovin volcanoes.

Genetics of Post-Traumatic Stress Disorder: Informing Clinical Conceptualizations and Promoting Future Research

PubMed Central

Nugent, Nicole R.; Amstadter, Ananda B.; Koenen, Karestan C.

2009-01-01

The purpose of this article is to provide an overview of genetic research involving post-traumatic stress disorder (PTSD). First, we summarize evidence for genetic influences on PTSD from family investigations. Second, we discuss the distinct contributions to our understanding of the genetics of PTSD permitted by twin studies. Finally, we summarize findings from molecular genetic studies, which have the potential to inform our understanding of underlying biological mechanisms for the development of PTSD. PMID:18412098

Evaluating and optimizing the NERSC workload on Knights Landing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Barnes, T; Cook, B; Deslippe, J

2017-01-30

NERSC has partnered with 20 representative application teams to evaluate performance on the Xeon-Phi Knights Landing architecture and develop an application-optimization strategy for the greater NERSC workload on the recently installed Cori system. In this article, we present early case studies and summarized results from a subset of the 20 applications highlighting the impact of important architecture differences between the Xeon-Phi and traditional Xeon processors. We summarize the status of the applications and describe the greater optimization strategy that has formed.

Evaluating and Optimizing the NERSC Workload on Knights Landing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Barnes, Taylor; Cook, Brandon; Doerfler, Douglas

2016-01-01

NERSC has partnered with 20 representative application teams to evaluate performance on the Xeon-Phi Knights Landing architecture and develop an application-optimization strategy for the greater NERSC workload on the recently installed Cori system. In this article, we present early case studies and summarized results from a subset of the 20 applications highlighting the impact of important architecture differences between the Xeon-Phi and traditional Xeon processors. We summarize the status of the applications and describe the greater optimization strategy that has formed.

What's new in multiple sclerosis spasticity research? Poster session highlights.

PubMed

Linker, Ralf

2017-11-01

Each year at the Multiple Sclerosis Experts Summit, relevant research in the field of multiple sclerosis spasticity is featured in poster sessions. The main studies presented at this year's meeting are summarized herein.

Locomotive crashworthiness research : executive summary

DOT National Transportation Integrated Search

1995-07-01

Four reports on a study to evaluate whether various crashworthiness features, as defined in Public Law 102-365, can provide practical benefit to the occupants of freight locomotives are summarized. In particular, the benefit was assessed relative to ...

Achondroplasia

MedlinePlus

... birth and infant mortality. Solving premature birth Featured articles Accomplishments and lessons learned since the establishment of ... The impact of premature birth on society Featured articles How long should you wait before getting pregnant ...

Mendeley: Creating Communities of Scholarly Inquiry through Research Collaboration

ERIC Educational Resources Information Center

Zaugg, Holt; West, Richard E.; Tateishi, Isaku; Randall, Daniel L.

2010-01-01

Mendeley is a free, web-based tool for organizing research citations and annotating their accompanying PDF articles. Adapting Web 2.0 principles for academic scholarship, Mendeley integrates the management of the research articles with features for collaborating with researchers locally and worldwide. In this article the features of Mendeley are…

Measuring the Interestingness of Articles in a Limited User Environment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pon, Raymond K.

Search engines, such as Google, assign scores to news articles based on their relevancy to a query. However, not all relevant articles for the query may be interesting to a user. For example, if the article is old or yields little new information, the article would be uninteresting. Relevancy scores do not take into account what makes an article interesting, which varies from user to user. Although methods such as collaborative filtering have been shown to be effective in recommendation systems, in a limited user environment, there are not enough users that would make collaborative filtering effective. A general framework,more » called iScore, is presented for defining and measuring the 'interestingness' of articles, incorporating user-feedback. iScore addresses various aspects of what makes an article interesting, such as topic relevancy, uniqueness, freshness, source reputation, and writing style. It employs various methods to measure these features and uses a classifier operating on these features to recommend articles. The basic iScore configuration is shown to improve recommendation results by as much as 20%. In addition to the basic iScore features, additional features are presented to address the deficiencies of existing feature extractors, such as one that tracks multiple topics, called MTT, and a version of the Rocchio algorithm that learns its parameters online as it processes documents, called eRocchio. The inclusion of both MTT and eRocchio into iScore is shown to improve iScore recommendation results by as much as 3.1% and 5.6%, respectively. Additionally, in TREC11 Adaptive Filter Task, eRocchio is shown to be 10% better than the best filter in the last run of the task. In addition to these two major topic relevancy measures, other features are also introduced that employ language models, phrases, clustering, and changes in topics to improve recommendation results. These additional features are shown to improve recommendation results by iScore by up to 14%. Due to varying reasons that users hold regarding why an article is interesting, an online feature selection method in naive Bayes is also introduced. Online feature selection can improve recommendation results in iScore by up to 18.9%. In summary, iScore in its best configuration can outperform traditional IR techniques by as much as 50.7%. iScore and its components are evaluated in the news recommendation task using three datasets from Yahoo! News, actual users, and Digg. iScore and its components are also evaluated in the TREC Adaptive Filter task using the Reuters RCV1 corpus.« less

Multimedia Learning: Beyond Modality. Commentary.

ERIC Educational Resources Information Center

Reimann, P.

2003-01-01

Identifies and summarizes instructional messages in the articles in this theme issue and also identifies central theoretical issues, focusing on: (1) external representations; (2) dual coding theory; and (3) the effects of animations on learning. (SLD)

Perivascular epithelioid cell neoplasms: pathology and pathogenesis.

PubMed

Folpe, Andrew L; Kwiatkowski, David J

2010-01-01

This review article summarizes our current understanding of the clinical, pathologic, immunohistochemical, and genetic aspects of perivascular epithelioid cell neoplasms, a rare group of related tumors defined by both morphologic and immunophenotypic criteria.

Should the Basket Be Lowered for Young Participants?

ERIC Educational Resources Information Center

Henry, George M.

1979-01-01

This article summarizes some of the current discussion concerning the height of the basketball goal. A system of graduated heights for elementary school, high school, college, and professional teams is suggested. (JMF)

Microbial Control News - November 2011

USDA-ARS?s Scientific Manuscript database

This is the first of a column in the Society for Invertebrate Pathology Newsletter. Entitled "Microbial Control News" this article summarizes regulatory actions in the U.S. and Canada regarding microbial insect pest control agents....

Rethinking Social Justice and Adult Education for Welcoming, Inclusive Communities: Synthesis of Themes

ERIC Educational Resources Information Center

Lange, Elizabeth; Baillie Abidi, Catherine

2015-01-01

This chapter summarizes the key themes across the articles on transnational migration, social inclusion, and adult education, using Nancy Fraser's framework of redistributive, recognitive, and representational justice.

Securing Information Technology in Healthcare

PubMed Central

Anthony, Denise; Campbell, Andrew T.; Candon, Thomas; Gettinger, Andrew; Kotz, David; Marsch, Lisa A.; Molina-Markham, Andrés; Page, Karen; Smith, Sean W.; Gunter, Carl A.; Johnson, M. Eric

2014-01-01

Dartmouth College’s Institute for Security, Technology, and Society conducted three workshops on securing information technology in healthcare, attended by a diverse range of experts in the field. This article summarizes the three workshops. PMID:25379030

Update in Hospice and Palliative Care.

PubMed

Taylor, Richard A; Smith, Cardinale B; Coats, Heather; Gelfman, Laura P; Dionne-Odom, J Nicholas

2017-11-01

The objective of this update, presented at the 2017 Annual Assembly of the American Association of Palliative and Hospice Medicine (AAHPM) and the Hospice and Palliative Nurses Association (HPNA), is to identify, summarize, and critique a sampling of research from the prior year that has the potential for marked impact on hospice and palliative clinical practice. Eight reports of original research published between January 1, 2016 and December 31, 2016 were identified through a systematic PubMed search using the terms "hospice" and "palliative care," a hand search of 22 leading healthcare journals, and discussion with experts in the field. Candidate articles were ranked based on the study's methodological quality, appeal to a breadth of palliative care clinicians across different settings, and potential clinical practice impact. We summarize the eight articles with the highest ratings and give recommendations for clinical practice.

Chromosomal Conditions

MedlinePlus

... birth and infant mortality. Solving premature birth Featured articles Accomplishments and lessons learned since the establishment of ... The impact of premature birth on society Featured articles How long should you wait before getting pregnant ...

Rh Disease

MedlinePlus

... birth and infant mortality. Solving premature birth Featured articles Accomplishments and lessons learned since the establishment of ... The impact of premature birth on society Featured articles How long should you wait before getting pregnant ...

Containerless protein crystal growth method

NASA Technical Reports Server (NTRS)

Rhim, Won-Kyu; Chung, Sang K.

1991-01-01

A method of growing protein crystals from levitated drops is introduced and unique features of containerless approach in 1-g and micro-G laboratories are discussed. Electrostatic multidrop levitation system which is capable of simultaneous four drop levitation is described. A method of controlling protein saturation level in a programmed way is introduced and discussed. Finally, some of the unique features of containerless approach of protein crystal growth in space are discussed and summarized.

Building the Foundation the WRITE WAY: Mini-Lessons with Practical Strategies for Teaching the Personal Narrative, Feature Article, "How-to..." Article, and Persuasive Letter.

ERIC Educational Resources Information Center

Miller, Susan A.; Vincent, Donna

This book presents strategies for teaching the personal narrative, feature article, how-to article, and persuasive letter, and for teaching fiction and reflective thinking and writing. It includes definitions, lesson plans, originals for transparencies and photocopies, and sample student writing. The first four sections are: Teaching the Personal…

Writing a review article - Are you making these mistakes?

PubMed

Daldrup-Link, Heike E

2018-01-01

An explosion of scientific publications over the last decades has increased the need for review articles: Carefully crafted scientific review articles can provide the novice reader with an overview of a new subject and provide the expert with a synthesis of scientific evidence, proof of reproducibility of published data and pooled estimates of common truth through meta-analyses. Unfortunately, while there are ample presentations and published guidelines for the preparation of scientific articles available, detailed information about how to properly prepare scientific review articles is relatively scarce. This perspective summarizes possible mistakes that can lead to misinformation in scientific review articles with the goal to help authors to improve the scientific contribution of their review article and thereby, increase the respective value of these articles for the scientific community.

How Organizations Can Enhance the Quality of Life of Their Clients and Assess Their Results: The Concept of QOL Enhancement

ERIC Educational Resources Information Center

Reinders, Hans S.; Schalock, Robert L.

2014-01-01

This article presents the framework of a dynamic approach to quality of life (QOL) enhancement based on the conceptualization and measurement of individual-referenced quality of life. Sections of the article summarize the premises of QOL enhancement, provide the rationale for a dynamic approach to QOL enhancement, discuss six components of QOL…

The place of robotics in gynecologic surgery.

PubMed

Quemener, J; Boulanger, L; Rubod, C; Cosson, M; Vinatier, D; Collinet, P

2012-10-01

Robot-assisted laparoscopic gynecologic surgery has undergone widespread development in recent years. The surgical literature on this subject continues to grow. The goal of this article is to summarize the principal indications for robotic assistance in gynecologic surgery and to offer a general overview of the principal articles dealing with robotic surgery for both benign and malignant disease. Copyright © 2012 Elsevier Masson SAS. All rights reserved.

The role of benefit transfer in ecosystem service valuation

USGS Publications Warehouse

Richardson, Leslie A.; Loomis, John; Kroeger, Timm; Casey, Frank

2015-01-01

The demand for timely monetary estimates of the economic value of nonmarket ecosystem goods and services has steadily increased over the last few decades. This article describes the use of benefit transfer to generate monetary value estimates of ecosystem services specifically. The article provides guidance for conducting such benefit transfers and summarizes advancements in benefit transfer methods, databases and analysis tools designed to facilitate its application.

Caring for Multiples

MedlinePlus

... birth and infant mortality. Solving premature birth Featured articles Accomplishments and lessons learned since the establishment of ... The impact of premature birth on society Featured articles How long should you wait before getting pregnant ...

Improving Naive Bayes with Online Feature Selection for Quick Adaptation to Evolving Feature Usefulness

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pon, R K; Cardenas, A F; Buttler, D J

The definition of what makes an article interesting varies from user to user and continually evolves even for a single user. As a result, for news recommendation systems, useless document features can not be determined a priori and all features are usually considered for interestingness classification. Consequently, the presence of currently useless features degrades classification performance [1], particularly over the initial set of news articles being classified. The initial set of document is critical for a user when considering which particular news recommendation system to adopt. To address these problems, we introduce an improved version of the naive Bayes classifiermore » with online feature selection. We use correlation to determine the utility of each feature and take advantage of the conditional independence assumption used by naive Bayes for online feature selection and classification. The augmented naive Bayes classifier performs 28% better than the traditional naive Bayes classifier in recommending news articles from the Yahoo! RSS feeds.« less

Benefits Mapping and Analysis Program (BenMAP)

EPA Pesticide Factsheets

This area summarizes the key features of the BenMAP-CE program and links to pages that provide more details regarding the program, the basic principles of air pollution benefits analysis and a link to download the software.

Wide-bandwidth high-resolution search for extraterrestrial intelligence

NASA Technical Reports Server (NTRS)

Horowitz, Paul

1993-01-01

Research accomplished during the third 6-month period is summarized. Research covered the following: dual-horn antenna performance; high electron mobility transistors (HEMT) low-noise amplifiers; downconverters; fast Fourier transform (FFT) array; and backend 'feature recognizer' array.

New approaches to investigating social gestures in autism spectrum disorder

PubMed Central

2012-01-01

The combination of economic games and human neuroimaging presents the possibility of using economic probes to identify biomarkers for quantitative features of healthy and diseased cognition. These probes span a range of important cognitive functions, but one new use is in the domain of reciprocating social exchange with other humans - a capacity perturbed in a number of psychopathologies. We summarize the use of a reciprocating exchange game to elicit neural and behavioral signatures for subjects diagnosed with autism spectrum disorder (ASD). Furthermore, we outline early efforts to capture features of social exchange in computational models and use these to identify quantitative behavioral differences between subjects with ASD and matched controls. Lastly, we summarize a number of subsequent studies inspired by the modeling results, which suggest new neural and behavioral signatures that could be used to characterize subtle deficits in information processing during interactions with other humans. PMID:22958572

Pregnancy Complications: Shoulder Dystocia

MedlinePlus

... birth and infant mortality. Solving premature birth Featured articles Accomplishments and lessons learned since the establishment of ... The impact of premature birth on society Featured articles How long should you wait before getting pregnant ...

Medications After the NICU

MedlinePlus

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Pregnancy Complications: Placental Abruption

MedlinePlus

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Amino Acid Metabolism Disorders

MedlinePlus

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Grandparents and the NICU

MedlinePlus

... birth and infant mortality. Solving premature birth Featured articles Accomplishments and lessons learned since the establishment of ... The impact of premature birth on society Featured articles How long should you wait before getting pregnant ...

The Education Deficit. A Staff Report Summarizing the Hearing on "Competitiveness and the Quality of the American Work Force," Prepared for the Use of the Subcommittee on Education and Health of the Joint Economic Committee. Congress of the United States, 101st Congress, First Session, December 14, 1988.

ERIC Educational Resources Information Center

Joint Economic Committee, Washington, DC.

This staff report summarizes testimony on competitiveness and the quality of the American work force. The testimony was received during 9 days of hearings held between September 23 and December 3, 1987, that featured 52 witnesses including federal and state officials, educators, business and labor leaders, and scholars. Contents comprise prepared…

Making Extensive Reading Even More Student Centered

ERIC Educational Resources Information Center

Jacobs, George M.; Renandya, Willy A.

2015-01-01

This article begins by explaining the student centered learning paradigm. Next, the article explains various features of a student centered approach to education and how extensive reading (ER), as it is most often practiced, fits with those features. The bulk of the article suggests how ER might be implemented to make it even more learner centered.

Tay-Sachs and Sandhoff Diseases

MedlinePlus

... birth and infant mortality. Solving premature birth Featured articles Accomplishments and lessons learned since the establishment of ... The impact of premature birth on society Featured articles How long should you wait before getting pregnant ...

PKU (Phenylketonuria) in Your Baby

MedlinePlus

... birth and infant mortality. Solving premature birth Featured articles Accomplishments and lessons learned since the establishment of ... The impact of premature birth on society Featured articles How long should you wait before getting pregnant ...

ABM Drag_Pass Report Generator

NASA Technical Reports Server (NTRS)

Fisher, Forest; Gladden, Roy; Khanampornpan, Teerapat

2008-01-01

dragREPORT software was developed in parallel with abmREPORT, which is described in the preceding article. Both programs were built on the capabilities created during that process. This tool generates a drag_pass report that summarizes vital information from the MRO aerobreaking drag_pass build process to facilitate both sequence reviews and provide a high-level summarization of the sequence for mission management. The script extracts information from the ENV, SSF, FRF, SCMFmax, and OPTG files, presenting them in a single, easy-to-check report providing the majority of parameters needed for cross check and verification as part of the sequence review process. Prior to dragReport, all the needed information was spread across a number of different files, each in a different format. This software is a Perl script that extracts vital summarization information and build-process details from a number of source files into a single, concise report format used to aid the MPST sequence review process and to provide a high-level summarization of the sequence for mission management reference. This software could be adapted for future aerobraking missions to provide similar reports, review and summarization information.

METAL PARTITIONING IN COMBUSTION PROCESSES

EPA Science Inventory

This article summarizes ongoing research efforts at the National Risk Management Research Laboratory of the U.S. Environmental Protection Agency examining [high temperature] metal behavior within combustion environments. The partitioning of non-volatile (Cr and Ni), semi-volatil...

An Overview of the Year 2000.

ERIC Educational Resources Information Center

Kutscher, Ronald E.

1988-01-01

This article indicates the sources of data and methods used to develop employment projections; summarizes the projections of the labor force, economic growth, industrial employment, and occupational employment; and discusses some important implications of the projections. (JOW)

The Origin of the Idea of the Mammal-like Reptile

ERIC Educational Resources Information Center

Aulie, Richard P.

1975-01-01

Conclusion of a three-part article in which the author discusses the implications for zoology and paleontology today and summarizes with comments on the "model" aspects of the controversy and its resolution. (BR)

Resistance Training: Physiological Responses and Adaptations (Part 2 of 4).

ERIC Educational Resources Information Center

Fleck, Stephen J.; Kraerner, William J.

1988-01-01

Resistance training causes a variety of physiological reactions, including changes in muscle size, connective tissue size, and bone mineral content. This article summarizes data from a variety of studies and research. (JL)

200 Years of Vocational Education, 1776-1976

ERIC Educational Resources Information Center

Barlow, Melvin L.

1976-01-01

The introduction to a series of articles on the 200-year history of vocational education in the United States summarizes major achievements during 50-year periods: 1776-1826, 1826-1876, 1876-1926, and 1926-1976. (EC)

The Design of Data Disaster Recovery of National Fundamental Geographic Information System

NASA Astrophysics Data System (ADS)

Zhai, Y.; Chen, J.; Liu, L.; Liu, J.

2014-04-01

With the development of information technology, data security of information system is facing more and more challenges. The geographic information of surveying and mapping is fundamental and strategic resource, which is applied in all areas of national economic, defence and social development. It is especially vital to national and social interests when such classified geographic information is directly concerning Chinese sovereignty. Several urgent problems that needs to be resolved for surveying and mapping are how to do well in mass data storage and backup, establishing and improving the disaster backup system especially after sudden natural calamity accident, and ensuring all sectors rapidly restored on information system will operate correctly. For overcoming various disaster risks, protect the security of data and reduce the impact of the disaster, it's no doubt the effective way is to analysis and research on the features of storage and management and security requirements, as well as to ensure that the design of data disaster recovery system suitable for the surveying and mapping. This article analyses the features of fundamental geographic information data and the requirements of storage management, three site disaster recovery system of DBMS plan based on the popular network, storage and backup, data replication and remote switch of application technologies. In LAN that synchronous replication between database management servers and the local storage of backup management systems, simultaneously, remote asynchronous data replication between local storage backup management systems and remote database management servers. The core of the system is resolving local disaster in the remote site, ensuring data security and business continuity of local site. This article focuses on the following points: background, the necessity of disaster recovery system, the analysis of the data achievements and data disaster recovery plan. Features of this program is to use a hardware-based data hot backup, and remote online disaster recovery support for Oracle database system. The achievement of this paper is in summarizing and analysing the common characteristics of disaster of surveying and mapping business system requirements, while based on the actual situation of the industry, designed the basic GIS disaster recovery solutions, and we also give the conclusions about key technologies of RTO and RPO.

Mammographic phenotypes of breast cancer risk driven by breast anatomy

NASA Astrophysics Data System (ADS)

Gastounioti, Aimilia; Oustimov, Andrew; Hsieh, Meng-Kang; Pantalone, Lauren; Conant, Emily F.; Kontos, Despina

2017-03-01

Image-derived features of breast parenchymal texture patterns have emerged as promising risk factors for breast cancer, paving the way towards personalized recommendations regarding women's cancer risk evaluation and screening. The main steps to extract texture features of the breast parenchyma are the selection of regions of interest (ROIs) where texture analysis is performed, the texture feature calculation and the texture feature summarization in case of multiple ROIs. In this study, we incorporate breast anatomy in these three key steps by (a) introducing breast anatomical sampling for the definition of ROIs, (b) texture feature calculation aligned with the structure of the breast and (c) weighted texture feature summarization considering the spatial position and the underlying tissue composition of each ROI. We systematically optimize this novel framework for parenchymal tissue characterization in a case-control study with digital mammograms from 424 women. We also compare the proposed approach with a conventional methodology, not considering breast anatomy, recently shown to enhance the case-control discriminatory capacity of parenchymal texture analysis. The case-control classification performance is assessed using elastic-net regression with 5-fold cross validation, where the evaluation measure is the area under the curve (AUC) of the receiver operating characteristic. Upon optimization, the proposed breast-anatomy-driven approach demonstrated a promising case-control classification performance (AUC=0.87). In the same dataset, the performance of conventional texture characterization was found to be significantly lower (AUC=0.80, DeLong's test p-value<0.05). Our results suggest that breast anatomy may further leverage the associations of parenchymal texture features with breast cancer, and may therefore be a valuable addition in pipelines aiming to elucidate quantitative mammographic phenotypes of breast cancer risk.

In the NICU: Your Family and Friends

MedlinePlus

... birth and infant mortality. Solving premature birth Featured articles Accomplishments and lessons learned since the establishment of ... The impact of premature birth on society Featured articles How long should you wait before getting pregnant ...

Biomechanics of Atherosclerotic Coronary Plaque: Site, Stability and In Vivo Elasticity Modeling

PubMed Central

Ohayon, Jacques; Finet, Gérard; Le Floc’h, Simon; Cloutier, Guy; Gharib, Ahmed M.; Heroux, Julie; Pettigrew, Roderic I.

2016-01-01

Coronary atheroma develop in local sites that are widely variable among patients and are considerably variable in their vulnerability for rupture. This article summarizes studies conducted by our collaborative laboratories on predictive biomechanical modeling of coronary plaques. It aims to give insights into the role of biomechanics in the development and localization of atherosclerosis, the morphologic features that determine vulnerable plaque stability, and emerging in vivo imaging techniques that may detect and characterize vulnerable plaque. Composite biomechanical and hemodynamic factors that influence the actual site of development of plaques have been studied. Plaque vulnerability, in vivo, is more challenging to assess. Important steps have been made in defining the biomechanical factors that are predictive of plaque rupture and the likelihood of this occurring if characteristic features are known. A critical key in defining plaque vulnerability is the accurate quantification of both the morphology and the mechanical properties of the diseased arteries. Recently, an early IVUS based palpography technique developed to assess local strain, elasticity and mechanical instabilities has been successfully revisited and improved to account for complex plaque geometries. This is based on an initial best estimation of the plaque components’ contours, allowing subsequent iteration for elastic modulus assessment as a basis for plaque stability determination. The improved method has also been preliminarily evaluated in patients with successful histologic correlation. Further clinical evaluation and refinement are on the horizon. PMID:24043605

Role of Green Spaces in Favorable Microclimate Creating in Urban Environment (Exemplified by Italian Cities)

NASA Astrophysics Data System (ADS)

Finaeva, O.

2017-11-01

The article represents a brief analysis of factors that influence the development of an urban green space system: territorial and climatic conditions, cultural and historical background as well as the modern strategy of historic cities development. The introduction defines the concept of urban greening, green spaces and green space distribution. The environmental parameters influenced by green spaces are determined. By the example of Italian cities the principles of the urban greening system development are considered: the historical aspects of formation of the urban greening system in Italian cities are analyzed, the role of green spaces in the formation of the urban environment structure and the creation of a favorable microclimate is determined, and a set of measures aimed at its improvement is highlighted. The modern principles of urban greening systems development and their characteristic features are considered. Special attention is paid to the interrelation of architectural and green structures in the formation of a favorable microclimate and psychological comfort in the urban environment; various methods of greening are considered by the example of existing architectural complexes depending on the climate of the area and the landscape features. The examples for the choice of plants and the application of compositional techniques are given. The results represent the basic principles of developing an urban green spaces system. The conclusion summarizes the techniques aimed at the microclimate improvement in the urban environment.

Performance Evaluation of the United Nations Environment Programme Air Quality Monitoring Unit

EPA Pesticide Factsheets

This report defines the specifics of the environmental test conditions used in the evaluation (systems and conditions), data observations, summarization of key performance evaluation findings, and ease of use features concerning the UNEP pod.

Collision risk model for NAT region.

DOT National Transportation Integrated Search

1971-05-01

The paper reviews and summarizes the essential features of the collision risk model used to analyze the effects of separation standards on safety for the parallel tracking system employed in the North Atlantic. The derivation of the model is traced f...

Black raspberry: Korean vs. American

USDA-ARS?s Scientific Manuscript database

This fact sheet shows Korean black raspberry (Rubus coreanus) fruit, flower, and leaf features that distinguish them from their Rubus relatives, black raspberry (R. occidentalis) native to America. Common names with fruit characteristics, including berry size and pigment fingerprints, are summarized...

Antarctic Meteorite Newsletter, volume 8, number 1

NASA Technical Reports Server (NTRS)

1985-01-01

Preliminary descriptions and classifications of meteorites examined since the July 1984 newsletter are presented. Each macroscopic description summarizes features that were visible to the eye (with, at most, 50X magnification). Each thin section description represents features that were found in a survey-level examination of a polished thin section that was prepared from a small (usually extrior) chip of the meteorite. Classification is based on microscopic petrography and reconnaissance-level electron-probe microanalyses.

Introduction to the special issue: under pressure.

PubMed

Howard, Yetta

2013-01-01

This article introduces this special issue on the theme "Under Pressure." It uses an analysis of experimental lesbian filmmaker Su Friedrich's Seeing Red (2005) to frame the issue's focus on the ways that the category "lesbian" is placed under pressure and/or the pressure "lesbian" places on twentieth- and twenty-first-century cultural production. After this overview, the introduction summarizes all seven articles in the order that they appear in the issue. These summaries also show the connections between the articles and suggest possibilities for future critical dialogues on the theme.

An Overview of Article III and Article XII, Senate Bill 1, 77th Legislature: General Appropriations Act--Agencies of Public Higher Education.

ERIC Educational Resources Information Center

Texas State Higher Education Coordinating Board, Austin. Div. of Research, Campus Planning and Finance.

Almost all the funds appropriated to state agencies and institutions of higher education in Texas for the 2002-2003 biennium are provided through Senate Bill 1, General Appropriations Act, 77th Legislature. This report summarizes the higher education portion of that act. The all funds appropriation for higher education for the biennium is $14.6…

Making It Work for Everyone: HTML5 and CSS Level 3 for Responsive, Accessible Design on Your Library's Web Site

ERIC Educational Resources Information Center

Baker, Stewart C.

2014-01-01

This article argues that accessibility and universality are essential to good Web design. A brief review of library science literature sets the issue of Web accessibility in context. The bulk of the article explains the design philosophies of progressive enhancement and responsive Web design, and summarizes recent updates to WCAG 2.0, HTML5, CSS…

Thermodynamic database for the Co-Pr system.

PubMed

Zhou, S H; Kramer, M J; Meng, F Q; McCallum, R W; Ott, R T

2016-03-01

In this article, we describe data on (1) compositions for both as-cast and heat treated specimens were summarized in Table 1; (2) the determined enthalpy of mixing of liquid phase is listed in Table 2; (3) thermodynamic database of the Co-Pr system in TDB format for the research articled entitle Chemical partitioning for the Co-Pr system: First-principles, experiments and energetic calculations to investigate the hard magnetic phase W.

Thermodynamic database for the Co-Pr system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhou, S. H.; Kramer, M. J.; Meng, F. Q.

2016-01-21

In this article, we describe data on (1) compositions for both as-cast and heat treated specimens were summarized in Table 1; (2) the determined enthalpy of mixing of liquid phase is listed in Table 2; (3) thermodynamic database of the Co-Pr system in TDB format for the research articled entitle Chemical partitioning for the Co-Pr system: First-principles, experiments and energetic calculations to investigate the hard magnetic phase W.

A Study to Document the Effects of Altering Traditional Dental School Recruitment and Admissions Policies for Minority Students. Volume IV: Appendices.

ERIC Educational Resources Information Center

Kell, Diane; And Others

A total of 84 citations is included in this bibliography. In addition, about one third of the articles have been abstracted; the rest are reviewed but not summarized. In general, the abstracted articles are judged to be the most useful in the conduct of this particular study, which evaluates the current position of minority students in dental…

Thermodynamic database for the Co-Pr system

DOE PAGES

Zhou, S. H.; Kramer, M. J.; Meng, F. Q.; ...

2016-03-01

In this article, we describe data on (1) compositions for both as-cast and heat treated specimens were summarized in Table 1; (2) the determined enthalpy of mixing of liquid phase is listed in Table 2; (3) thermodynamic database of the Co-Pr system in TDB format for the research articled entitled ''Chemical partitioning for the Co-Pr system: First-principles, experiments and energetic calculations to investigate the hard magnetic phase W.''

Unit of Analysis: Impact of Silverman and Solmon's Article on Field-Based Intervention Research in Physical Education in the U.S.A.

ERIC Educational Resources Information Center

Li, Weidong; Chen, Yung-Ju; Xiang, Ping; Xie, Xiuge; Li, Yilin

2017-01-01

Purpose: The purposes of this study were to: (a) examine the impact of the Silverman and Solmon article (1998) on how researchers handle the unit of analysis issue in their field-based intervention research in physical education in the United States and summarize statistical approaches that have been used to analyze the data, and (b) provide…

Approach to Reptile Emergency Medicine.

PubMed

Long, Simon Y

2016-05-01

This article summarizes the physiology and anatomy of reptiles, highlighting points relevant for emergency room veterinarians. Other systems, such as the endocrine and immune systems, have not been covered. The many other aspects of reptile species variation are too numerous to be covered. This article provides an overview but encourages clinicians to seek additional species-specific information to better medically diagnose and treat their reptile patients. Copyright © 2016 Elsevier Inc. All rights reserved.

Big data in psychology: Introduction to the special issue.

PubMed

Harlow, Lisa L; Oswald, Frederick L

2016-12-01

The introduction to this special issue on psychological research involving big data summarizes the highlights of 10 articles that address a number of important and inspiring perspectives, issues, and applications. Four common themes that emerge in the articles with respect to psychological research conducted in the area of big data are mentioned, including: (a) The benefits of collaboration across disciplines, such as those in the social sciences, applied statistics, and computer science. Doing so assists in grounding big data research in sound theory and practice, as well as in affording effective data retrieval and analysis. (b) Availability of large data sets on Facebook, Twitter, and other social media sites that provide a psychological window into the attitudes and behaviors of a broad spectrum of the population. (c) Identifying, addressing, and being sensitive to ethical considerations when analyzing large data sets gained from public or private sources. (d) The unavoidable necessity of validating predictive models in big data by applying a model developed on 1 dataset to a separate set of data or hold-out sample. Translational abstracts that summarize the articles in very clear and understandable terms are included in Appendix A, and a glossary of terms relevant to big data research discussed in the articles is presented in Appendix B. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

Big Data in Psychology: Introduction to Special Issue

PubMed Central

Harlow, Lisa L.; Oswald, Frederick L.

2016-01-01

The introduction to this special issue on psychological research involving big data summarizes the highlights of 10 articles that address a number of important and inspiring perspectives, issues, and applications. Four common themes that emerge in the articles with respect to psychological research conducted in the area of big data are mentioned, including: 1. The benefits of collaboration across disciplines, such as those in the social sciences, applied statistics, and computer science. Doing so assists in grounding big data research in sound theory and practice, as well as in affording effective data retrieval and analysis. 2. Availability of large datasets on Facebook, Twitter, and other social media sites that provide a psychological window into the attitudes and behaviors of a broad spectrum of the population. 3. Identifying, addressing, and being sensitive to ethical considerations when analyzing large datasets gained from public or private sources. 4. The unavoidable necessity of validating predictive models in big data by applying a model developed on one dataset to a separate set of data or hold-out sample. Translational abstracts that summarize the articles in very clear and understandable terms are included in Appendix A, and a glossary of terms relevant to big data research discussed in the articles is presented in Appendix B. PMID:27918177

Nasal Septal Deviations: A Systematic Review of Classification Systems.

PubMed

Teixeira, Jeffrey; Certal, Victor; Chang, Edward T; Camacho, Macario

2016-01-01

Objective. To systematically review the international literature for internal nasal septal deviation classification systems and summarize them for clinical and research purposes. Data Sources. Four databases (including PubMed/MEDLINE) were systematically searched through December 16, 2015. Methods. Systematic review, adhering to PRISMA. Results. After removal of duplicates, this study screened 952 articles for relevance. A final comprehensive review of 50 articles identified that 15 of these articles met the eligibility criteria. The classification systems defined in these articles included C-shaped, S-shaped, reverse C-shaped, and reverse S-shaped descriptions of the septal deviation in both the cephalocaudal and anteroposterior dimensions. Additional studies reported use of computed tomography and categorized deviation based on predefined locations. Three studies graded the severity of septal deviations based on the amount of deflection. The systems defined in the literature also included an evaluation of nasal septal spurs and perforations. Conclusion. This systematic review ascertained that the majority of the currently published classification systems for internal nasal septal deviations can be summarized by C-shaped or reverse C-shaped, as well as S-shaped or reverse S-shaped deviations in the anteroposterior and cephalocaudal dimensions. For imaging studies, predefined points have been defined along the septum. Common terminology can facilitate future research.

Contribution of Harold M. Swartz to In Vivo EPR and EPR Dosimetry.

PubMed

Gallez, Bernard

2016-12-01

In 2015, we are celebrating half a century of research in the application of Electron Paramagnetic Resonance (EPR) as a biodosimetry tool to evaluate the dose received by irradiated people. During the EPR Biodose 2015 meeting, a special session was organized to acknowledge the pioneering contribution of Harold M. (Hal) Swartz in the field. The article summarizes his main contribution in physiology and medicine. Four emerging themes have been pursued continuously along his career since its beginning: (1) radiation biology; (2) oxygen and oxidation; (3) measuring physiology in vivo; and (4) application of these measurements in clinical medicine. The common feature among all these different subjects has been the use of magnetic resonance techniques, especially EPR. In this article, you will find an impressionist portrait of Hal Swartz with the description of the 'making of' this pioneer, a time-line perspective on his career with the creation of three National Institutes of Health-funded EPR centers, a topic-oriented perspective on his career with a description of his major contributions to Science, his role as a mentor and his influence on his academic children, his active role as founder of scientific societies and organizer of scientific meetings, and the well-deserved international recognition received so far. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

The Effectiveness of Social Robots for Older Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Studies.

PubMed

Pu, Lihui; Moyle, Wendy; Jones, Cindy; Todorovic, Michael

2018-06-12

Social robots may promote the health of older adults by increasing their perceived emotional support and social interaction. This review aims to summarize the effectiveness of social robots on outcomes (psychological, physiological, quality of life, or medications) of older adults from randomized controlled trials (RCTs). A mixed-method systematic review of RCTs meeting the study inclusion criteria was undertaken. Eight databases were electronically searched up to September 2017. Participants' characteristics, intervention features, and outcome data were retrieved. The mean difference and standardized mean difference with 95% confidence intervals (CI) were synthesized to pool the effect size. A total of 13 articles from 11 RCTs were identified from 2,204 articles, of which 9 studies were included in the meta-analysis. Risk of bias was relatively high in allocation concealment and blinding. Social robots appeared to have positive impacts on agitation, anxiety, and quality of life for older adults but no statistical significance was found in the meta-analysis. However, results from a narrative review indicated that social robot interactions could improve engagement, interaction, and stress indicators, as well as reduce loneliness and the use of medications for older adults. Social robots appear to have the potential to improve the well-being of older adults, but conclusions are limited due to the lack of high-quality studies. More RCTs are recommended with larger sample sizes and rigorous study designs.

Report of mass communication Ceylon: October 1969-December 31, 1970.

PubMed

1971-01-01

Experience with media usage by the FPA (Family Planning Association of Ceylon between October 1969 and December 1970 is summarized. During this time, the Association purchased 100-200 column inches each of contract advertising space in 26 newspapers. The press has published 268 press release, I.P.P.F., U.N., features and international press clipping in addition to specialized medical articles on family planning methods and 8 articles by FPA office-bearers. In January 1970; the Association launched local radio's first 5-minute daily commercial in Sinhala and Tamil. The program was repeated from April to July 1970. A series of 5 slides on family planning has been shown in movie theathers and more sets are being prepared for viewing. Posters have been used on buses and are currently on display on the National Railways project. Folders, leaflect, and poster calendars have been produced and used. Family Planning stickers have put up in 700 barber saloons. The FPA had stalls in the 1970 3-day National Exhibition at Batticaloa, the 4-day U.N. Poster Exhibition at Badulla, and the 2-week Ceylon Medical College Centenary Exhibition in Colombo. The Information Unit of FPA has answered 18, 541 written inquiries. A family planning communication us regularly dispatched to members of the Cabinet, government and opposition members of parliament, senators, chairmen of local bodies, and key trade union officials.

Noninvasive Intracranial Pressure Monitoring for Severe Traumatic Brain Injury in Children: A Concise Update on Current Methods.

PubMed

Narayan, Vinayak; Mohammed, Nasser; Savardekar, Amey R; Patra, Devi Prasad; Notarianni, Christina; Nanda, Anil

2018-06-01

Traumatic brain injury (TBI) is a leading cause of pediatric morbidity and mortality worldwide and intracranial pressure (ICP) monitoring plays a crucial role in its management. Based on existing literature, we review the current practicing noninvasive ICP monitoring devices and their accuracy in predicting increased ICP in pediatric TBI. A thorough literature search was conducted on PubMed, Medline, and the Cochrane database, articles were selected systematically and reviewed completely, and relevant data were summarized and discussed. A total of 27 articles pertaining to pediatric TBI were included and reviewed. We found various modalities of noninvasive ICP monitoring devices used over the last few years. The noninvasive modalities so far attempted in pediatric TBI and so reviewed here are transcranial Doppler, optic nerve sheath diameter, otoacoustic emission, near-infrared spectroscopy, contrast-enhanced ultrasonography, and quantitative pupillometry. Invasive monitoring methods are the current gold standard for monitoring ICP; however, complications caused by their invasive nature are of concern. Of all the noninvasive methods based on the literature, we found transcranial Doppler and optic nerve sheath diameter assessment to be the best tools to monitor ICP in pediatric TBI. The promising results and developments of noninvasive ICP monitoring modalities with its ideal features of high sensitivity, diagnostic accuracy, and simple acquisition technique may make it the future of neurointensive monitoring in pediatric TBI. Copyright © 2018 Elsevier Inc. All rights reserved.

[Review of digital ground object spectral library].

PubMed

Zhou, Xiao-Hu; Zhou, Ding-Wu

2009-06-01

A higher spectral resolution is the main direction of developing remote sensing technology, and it is quite important to set up the digital ground object reflectance spectral database library, one of fundamental research fields in remote sensing application. Remote sensing application has been increasingly relying on ground object spectral characteristics, and quantitative analysis has been developed to a new stage. The present article summarized and systematically introduced the research status quo and development trend of digital ground object reflectance spectral libraries at home and in the world in recent years. Introducing the spectral libraries has been established, including desertification spectral database library, plants spectral database library, geological spectral database library, soil spectral database library, minerals spectral database library, cloud spectral database library, snow spectral database library, the atmosphere spectral database library, rocks spectral database library, water spectral database library, meteorites spectral database library, moon rock spectral database library, and man-made materials spectral database library, mixture spectral database library, volatile compounds spectral database library, and liquids spectral database library. In the process of establishing spectral database libraries, there have been some problems, such as the lack of uniform national spectral database standard and uniform standards for the ground object features as well as the comparability between different databases. In addition, data sharing mechanism can not be carried out, etc. This article also put forward some suggestions on those problems.

Family physicians' interests in special features of electronic publication

PubMed Central

Torre, Dario M.; Wright, Scott M.; Wilson, Renee F.; Diener-West, Marie; Bass, Eric B.

2003-01-01

Objective: Because many of the medical journals read by family physicians now have an electronic version, the authors conducted a survey to determine the interest of family physicians in specific features of electronic journal publications. Setting and Participants: We surveyed 175 family physicians randomly selected from the American Academy of Family Physicians. Results: The response rate was 63%. About half of family physicians reported good to excellent computer proficiency, and about one quarter used online journals sometimes or often. Many respondents reported high interest in having links to: an electronic medical text (48% for original articles, 56% for review articles), articles' list of references (52% for original articles, 56% for review articles), and health-related Websites (48% for original and review articles). Conclusion: Primary care–oriented journals should consider the interests of family physicians when developing and offering electronic features for their readers. PMID:12883561

The Transformation of Disabilities Organizations

ERIC Educational Resources Information Center

Schalock, Robert L.; Verdugo, Miguel-Angel

2013-01-01

This article summarizes the five major characteristics of the transformation era and describes how intellectual and closely related developmental disabilities organizations can apply specific transformation strategies associated with each characteristic. Collectively, the characteristics and strategies provide a framework for transformation…

What's My Line?

ERIC Educational Resources Information Center

Walters, Donna

1994-01-01

Presents a humorous approach to the question of how to recycle catalog cards necessitated by the results of library automation and online catalogs. A sidebar summarizes an article that appeared in the "New Yorker" magazine regarding the discard of card catalogs. (LRW)

Japanese Management Styles: Can Academic Libraries Learn from Them?

ERIC Educational Resources Information Center

Graham, Paul

1987-01-01

Summarizes the three main characteristics of Japanese management style and discusses its applicability to academic library management in the United States. Responses from 10 readers of advance copies of the article are included. (6 references) (MES)

Antibacterial activity in adhesive dentistry: a literature review.

PubMed

Shafiei, Fereshteh; Memarpour, Mahtab

2012-01-01

This literature review summarizes the published research regarding the antibacterial agents used in adhesive dentistry. This article provides information about the clinical applications, beneficial effects, and possible disadvantages of antibacterials when used in various bonding situations.

IMPROVING WATERBORNE DISEASE OUTBREAK INVESTIGATIONS

EPA Science Inventory

This article summarizes the discussions and conclusions of a workshop held December 7-8, 1998, to consider the inherent limitations and weaknesses of waterborne outbreak investigations and make recommendations for their improvement. In recent years, an increased number of suspec...

Ketosis treatment in lactating dairy cattle.

PubMed

Gordon, Jessica L; Leblanc, Stephen J; Duffield, Todd F

2013-07-01

This article provides an update on ketosis treatment regimens. The ketosis treatment literature is reviewed and the findings are summarized. Current treatment recommendations and areas for future research are provided. Copyright © 2013 Elsevier Inc. All rights reserved.

Playing It Safe: Part I.

ERIC Educational Resources Information Center

Penman, Kenneth A.; Niccolai, Frances R.

1985-01-01

The first of a series of articles explains the legal principles of tort liability, waiver of liability, comparative negligence, assumption of risk, and contributory negligence. Summarizes the kinds of cases going to court involving sport facility design and operation. (MLF)

[Medical ecology: some results and research perspectives].

PubMed

Efimova, N V; Rukavishnikov, V S

2010-01-01

The article summarizes materials of long-standing research evaluating influence of environmental (natural and anthropogenous) factors on health state of various population groups (exemplified by Siberia). The authors defined leading problems and ways of medical ecology development.

Early Childhood Curricula. ERIC/EECE Report.

ERIC Educational Resources Information Center

Cesarone, Bernard

2003-01-01

Summarizes recent ERIC documents and journal articles, and highlights some World Wide Web resources that describe, evaluate, or compare various curricula or instructional methods, such as Creative Curriculum, High/Scope, the Montessori Method, Waldorf Schools, and Direct Instruction. (Author)

Water/Wastewater Treatment Plant Operator Qualifications.

ERIC Educational Resources Information Center

Water and Sewage Works, 1979

1979-01-01

This article summarizes in tabular form the U.S. and Canadian programs for classification of water and wastewater treatment plant personnel. Included are main characteristics of the programs, educational and experience requirements, and indications of requirement substitutions. (CS)

Treacher Collins syndrome: New insights from animal models.

PubMed

Tse, William Ka Fai

2016-12-01

Treacher Collins syndrome (TCS, OMIM: 154500), an autosomal-dominant craniofacial developmental syndrome that occurs in 1 out of every 50,000 live births, is characterized by craniofacial malformation. Mutations in TCOF1, POLR1C, or POLR1D have been identified in affected individuals. In addition to established mouse models, zebrafish models have recently emerged as an valuable method to study facial disease. In this report, we summarized the two updated articles working on the pathogenesis of the newly identified polr1c and polr1d TCS mutations (Lau et al., 2016; Noack Watt et al., 2016) and discussed the possibility of using the anti-oxidants to prevent or rescue the TCS facial phenotype (Sakai et al., 2016). Taken together, this article provides an update on the disease from basic information to pathogenesis, and further summarizes the suggested therapies from recent laboratory research. Copyright © 2016 Elsevier Ltd. All rights reserved.

Diffusivities of Ag, Cs, Sr, and Kr in TRISO fuel particles and graphite

DOE Office of Scientific and Technical Information (OSTI.GOV)

Collin, Blaise Paul

Tri-structural isotropic (TRISO) coated particles have been developed and studied since the late 1950s when the concept of coated particles was invented by Roy Huddle of the United Kingdom Atomic Energy Authority. Several decades of work by half a dozen countries on fission product transport in TRISO fuel through numerous irradiation and heating experiments have led to several recommendations of transport data and to the adoption of various sets of diffusion coefficients. In 1997, the International Atomic Energy Agency (IAEA) gathered all these historical results and issued a technical document (TECDOC-978 [IAEA]) that summarizes these sets of recommended diffusion coefficients.more » Table 1 shows the reference literature articles for the diffusivities that have historically been recommended by the American and German TRISO fuel development programs and that are summarized in the IAEA report (see section 7 for full references of these articles).« less

The health effects of exercising in air pollution.

PubMed

Giles, Luisa V; Koehle, Michael S

2014-02-01

The health benefits of exercise are well known. Many of the most accessible forms of exercise, such as walking, cycling, and running often occur outdoors. This means that exercising outdoors may increase exposure to urban air pollution. Regular exercise plays a key role in improving some of the physiologic mechanisms and health outcomes that air pollution exposure may exacerbate. This problem presents an interesting challenge of balancing the beneficial effects of exercise along with the detrimental effects of air pollution upon health. This article summarizes the pulmonary, cardiovascular, cognitive, and systemic health effects of exposure to particulate matter, ozone, and carbon monoxide during exercise. It also summarizes how air pollution exposure affects maximal oxygen consumption and exercise performance. This article highlights ways in which exercisers could mitigate the adverse health effects of air pollution exposure during exercise and draws attention to the potential importance of land use planning in selecting exercise facilities.

Modeling in Big Data Environments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Endert, Alexander; Szymczak, Samantha; Gunning, Dave

Human-Centered Big Data Research (HCBDR) is an area of work that focuses on the methodologies and research areas focused on understanding how humans interact with “big data”. In the context of this paper, we refer to “big data” in a holistic sense, including most (if not all) the dimensions defining the term, such as complexity, variety, velocity, veracity, etc. Simply put, big data requires us as researchers of to question and reconsider existing approaches, with the opportunity to illuminate new kinds of insights that were traditionally out of reach to humans. The purpose of this article is to summarize themore » discussions and ideas about the role of models in HCBDR at a recent workshop. Models, within the context of this paper, include both computational and conceptual mental models. As such, the discussions summarized in this article seek to understand the connection between these two categories of models.« less

Automatic summarization of changes in biological image sequences using algorithmic information theory.

PubMed

Cohen, Andrew R; Bjornsson, Christopher S; Temple, Sally; Banker, Gary; Roysam, Badrinath

2009-08-01

An algorithmic information-theoretic method is presented for object-level summarization of meaningful changes in image sequences. Object extraction and tracking data are represented as an attributed tracking graph (ATG). Time courses of object states are compared using an adaptive information distance measure, aided by a closed-form multidimensional quantization. The notion of meaningful summarization is captured by using the gap statistic to estimate the randomness deficiency from algorithmic statistics. The summary is the clustering result and feature subset that maximize the gap statistic. This approach was validated on four bioimaging applications: 1) It was applied to a synthetic data set containing two populations of cells differing in the rate of growth, for which it correctly identified the two populations and the single feature out of 23 that separated them; 2) it was applied to 59 movies of three types of neuroprosthetic devices being inserted in the brain tissue at three speeds each, for which it correctly identified insertion speed as the primary factor affecting tissue strain; 3) when applied to movies of cultured neural progenitor cells, it correctly distinguished neurons from progenitors without requiring the use of a fixative stain; and 4) when analyzing intracellular molecular transport in cultured neurons undergoing axon specification, it automatically confirmed the role of kinesins in axon specification.

Boron Nitride Nanotubes: Recent Advances in Their Synthesis, Functionalization, and Applications.

PubMed

Lee, Chee Huei; Bhandari, Shiva; Tiwari, Bishnu; Yapici, Nazmiye; Zhang, Dongyan; Yap, Yoke Khin

2016-07-15

A comprehensive overview of current research progress on boron nitride nanotubes (BNNTs) is presented in this article. Particularly, recent advancements in controlled synthesis and large-scale production of BNNTs will first be summarized. While recent success in mass production of BNNTs has opened up new opportunities to implement the appealing properties in various applications, concerns about product purity and quality still remain. Secondly, we will summarize the progress in functionalization of BNNTs, which is the necessary step for their applications. Additionally, selected potential applications in structural composites and biomedicine will be highlighted.

Summarizing health inequalities in a Balanced Scorecard. Methodological considerations.

PubMed

Auger, Nathalie; Raynault, Marie-France

2006-01-01

The association between social determinants and health inequalities is well recognized. What are now needed are tools to assist in disseminating such information. This article describes how the Balanced Scorecard may be used for summarizing data on health inequalities. The process begins by selecting appropriate social groups and indicators, and is followed by the measurement of differences across person, place, or time. The next step is to decide whether to focus on absolute versus relative inequality. The last step is to determine the scoring method, including whether to address issues of depth of inequality.

The year 2013 in the European Heart Journal--Cardiovascular Imaging: Part II.

PubMed

Plein, Sven; Edvardsen, Thor; Pierard, Luc A; Saraste, Antti; Knuuti, Juhani; Maurer, Gerald; Lancellotti, Patrizio

2014-08-01

The new multi-modality cardiovascular imaging journal, European Heart Journal - Cardiovascular Imaging, was created in 2012. Here we summarize the most important studies from the journal's second year in two articles. Part I of the review has summarized studies in myocardial function, myocardial ischaemia, and emerging techniques in cardiovascular imaging. Part II is focussed on valvular heart diseases, heart failure, cardiomyopathies, and congenital heart diseases. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2014. For permissions please email: journals.permissions@oup.com.

Sexual dysfunctions in women.

PubMed

Meston, Cindy M; Bradford, Andrea

2007-01-01

In this article, we summarize the definition, etiology, assessment, and treatment of sexual dysfunctions in women. Although the Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV-TR) is our guiding framework for classifying and defining women's sexual dysfunctions, we draw special attention to recent discussion in the literature criticizing the DSM-IV-TR diagnostic criteria and their underlying assumptions. Our review of clinical research on sexual dysfunction summarizes psychosocial and biomedical management approaches, with a critical examination of the empirical support for commonly prescribed therapies and limitations of recent clinical trials.

'Limits and current knowledge of Pick's disease: its differential diagnosis'. A translation of the 1957 Delay, Brion, Escourolle article.

PubMed

Thibodeau, Marie-Pierre; Miller, Bruce L

2013-01-01

This article is a translation of a French article by Delay, Brion, and Escourolle. In a seminal article published in French in 1957 these authors summarized the work of previous researchers and reviewed a wide sample of frontotemporal dementia (FTD) cases formerly referred to as Pick's disease. The authors were among the first to define the critical clinical and anatomical differences between Alzheimer's disease (AD) and FTD and they even delineated distinctive FTD subtypes making possible the advances that now constitute the base of our studies. Reviewing their work allows us to appreciate the progress research has made.

The New Segregation.

ERIC Educational Resources Information Center

Laosa, Luis M.

2001-01-01

This issue reviews national demographic trends in school segregation, summarizing research findings. Though the national debate on school segregation emphasizes blacks and whites, present-day school segregation includes segregation by socioeconomic level, ethnicity, and native language. The research study examined features of the ecology of…

Feature Selection for Evolutionary Commercial-off-the-Shelf Software: Studies Focusing on Time-to-Market, Innovation and Hedonic-Utilitarian Trade-Offs

ERIC Educational Resources Information Center

Kakar, Adarsh Kumar

2013-01-01

Feature selection is one of the most important decisions made by product managers. This three article study investigates the concepts, tools and techniques for making trade-off decisions of introducing new features in evolving Commercial-Off-The-Shelf (COTS) software products. The first article investigates the efficacy of various feature…

Integrating statistical and clinical research elements in intervention-related grant applications: summary from an NIMH workshop.

PubMed

Sherrill, Joel T; Sommers, David I; Nierenberg, Andrew A; Leon, Andrew C; Arndt, Stephan; Bandeen-Roche, Karen; Greenhouse, Joel; Guthrie, Donald; Normand, Sharon-Lise; Phillips, Katharine A; Shear, M Katherine; Woolson, Robert

2009-01-01

The authors summarize points for consideration generated in a National Institute of Mental Health (NIMH) workshop convened to provide an opportunity for reviewers from different disciplines-specifically clinical researchers and statisticians-to discuss how their differing and complementary expertise can be well integrated in the review of intervention-related grant applications. A 1-day workshop was convened in October, 2004. The workshop featured panel presentations on key topics followed by interactive discussion. This article summarizes the workshop and subsequent discussions, which centered on topics including weighting the statistics/data analysis elements of an application in the assessment of the application's overall merit; the level of statistical sophistication appropriate to different stages of research and for different funding mechanisms; some key considerations in the design and analysis portions of applications; appropriate statistical methods for addressing essential questions posed by an application; and the role of the statistician in the application's development, study conduct, and interpretation and dissemination of results. A number of key elements crucial to the construction and review of grant applications were identified. It was acknowledged that intervention-related studies unavoidably involve trade-offs. Reviewers are helped when applications acknowledge such trade-offs and provide good rationale for their choices. Clear linkage among the design, aims, hypotheses, and data analysis plan and avoidance of disconnections among these elements also strengthens applications. The authors identify multiple points to consider when constructing intervention-related grant applications. The points are presented here as questions and do not reflect institute policy or comprise a list of best practices, but rather represent points for consideration.

Nosological status and definition of schizophrenia: Some considerations for DSM-V and ICD-11.

PubMed

Tandon, Rajiv; Maj, Mario

2008-12-01

Although dementia praecox or schizophrenia has been considered a unique disease entity for the past century, its definitions and boundaries have varied over this period. In this article, we examine the changing conceptualization of schizophrenia over the past 100 years and make some recommendations with regards to its definition in DSM-V and ICD-11. We summarize clinical features of schizophrenia in terms of symptomatology, course, and outcome. We examine factors that lead to changing definitions of a disorder such as schizophrenia, with specific reference to the evolution of its definition from DSM-1 (American Psychiatric Association, Washington, DC, 1952) to the current DSM-IV-TR. Efforts to elucidate the etiology and pathophysiology of schizophrenia have been hampered by its imprecise definition and continuing transformations in its conceptualization. The definition of schizophrenia, at any given time, has been influenced by available diagnostic tools and treatments, other clinical considerations, extant knowledge and scientific paradigms. It is now clear that schizophrenia does not represent a single disease with a unitary etiology or pathogenetic process. Despite limitations in the concept, however, alternative approaches thus far have been unsuccessful in better defining the syndrome of schizophrenia or its component entities. Whereas changing definitions of schizophrenia might impede research into its nature and development of more effective treatments, only a better understanding of schizophrenia can lead to its more precise definition. We consider the implications of our observations for DSM-V and ICD-11 definitions of schizophrenia and summarize some emerging preliminary recommendations. Copyright © 2008 Elsevier B.V. All rights reserved.

Knowledge Management and Academic Libraries.

ERIC Educational Resources Information Center

Townley, Charles T.

2001-01-01

The emerging field of knowledge management offers academic libraries the opportunity to improve effectiveness, both for themselves and their parent institutions. This article summarizes knowledge management theory. Current applications in academic libraries and higher education are described. Similarities and difficulties between knowledge…