Sample records for fenol con hierro

  1. Spatial vent opening probability map of El Hierro Island (Canary Islands, Spain)

    NASA Astrophysics Data System (ADS)

    Becerril, Laura; Cappello, Annalisa; Galindo, Inés; Neri, Marco; Del Negro, Ciro

    2013-04-01

    The assessment of the probable spatial distribution of new eruptions is useful to manage and reduce the volcanic risk. It can be achieved in different ways, but it becomes especially hard when dealing with volcanic areas less studied, poorly monitored and characterized by a low frequent activity, as El Hierro. Even though it is the youngest of the Canary Islands, before the 2011 eruption in the "Las Calmas Sea", El Hierro had been the least studied volcanic Island of the Canaries, with more historically devoted attention to La Palma, Tenerife and Lanzarote. We propose a probabilistic method to build the susceptibility map of El Hierro, i.e. the spatial distribution of vent opening for future eruptions, based on the mathematical analysis of the volcano-structural data collected mostly on the Island and, secondly, on the submerged part of the volcano, up to a distance of ~10-20 km from the coast. The volcano-structural data were collected through new fieldwork measurements, bathymetric information, and analysis of geological maps, orthophotos and aerial photographs. They have been divided in different datasets and converted into separate and weighted probability density functions, which were then included in a non-homogeneous Poisson process to produce the volcanic susceptibility map. Future eruptive events on El Hierro is mainly concentrated on the rifts zones, extending also beyond the shoreline. The major probabilities to host new eruptions are located on the distal parts of the South and West rifts, with the highest probability reached in the south-western area of the West rift. High probabilities are also observed in the Northeast and South rifts, and the submarine parts of the rifts. This map represents the first effort to deal with the volcanic hazard at El Hierro and can be a support tool for decision makers in land planning, emergency plans and civil defence actions.

  2. Full-Vector Geomagnetic Field Records for the Late Quaternary from El Hierro and the Eifel

    NASA Astrophysics Data System (ADS)

    Monster, M.; de Groot, L. V.; Dekkers, M. J.; van Galen, J. P.; Kuiper, K.; Langemeijer, J.; Wiarda, L. R.

    2015-12-01

    Twenty-eight flows in the age range of c. 100 to c. 500 ka were sampled on the island of El Hierro (Canary Islands, Spain) and twelve in the Eifel (Germany). All sites from the Eifel had been previously dated, whereas the ages of the El Hierro flows were approximated by stratigraphic and directional coherency with a dated section c. 4 km to the north-east. Additionally, seven flows were dated using the ThermoFisher Helix multi-collector mass spectrometer at VU University Amsterdam (the Netherlands). The rocks were subjected to standard rock magnetic and palaeomagnetic experiments. Palaeodirections were obtained using both thermal and alternating-field demagnetisation techniques. Apart from two sites that appear to have been struck by lightning, all sites yielded reliable palaeodirections. Absolute palaeointensities were obtained using three different methods: IZZI-Thellier, the multispecimen protocol and the calibrated pseudo-Thellier technique. Nineteen sites from El Hierro and all twelve sites from the Eifel passed the selection criteria for one or more of these methods, with the pseudo-Thellier technique having the highest success rate (c. 35% for El Hierro and 55% for the Eifel). The palaeointensities obtained for El Hierro were mostly between 20 and 40 μT and for the Eifel between 20 and 50 μT, both with a tendency to be somewhat low compared to the present-day field of c. 39 μT and c. 49 μT, respectively. The pseudo-Thellier and multispecimen methods generally yielded lower palaeointensities than IZZI-Thellier, but no clear trend was visible.

  3. Soil gas radon and volcanic activity at El Hierro (Canary Islands) before and after the 2011-2012 submarine eruption

    NASA Astrophysics Data System (ADS)

    Barrancos, J.; Padilla, G.; Hernandez Perez, P. A.; Padron, E.; Perez, N.; Melian Rodriguez, G.; Nolasco, D.; Dionis, S.; Rodriguez, F.; Calvo, D.; Hernandez, I.

    2012-12-01

    El Hierro is the youngest and southernmost island of the Canarian archipelago and represents the summit of a volcanic shield elevating from the surrounding seafloor at depth of 4000 m to up to 1501 m above sea level. The island is believed to be near the present hotspot location in the Canaries with the oldest subaerial rocks dated at 1.12 Ma. The subaerial parts of the El Hierro rift zones (NE, NW and S Ridges) are characterized by tightly aligned dyke complexes with clusters of cinder cones as their surface expressions. Since July 16, 2011, an anomalous seismicity at El Hierro Island was recorded by IGN seismic network. Volcanic tremor started at 05:15 hours on October 10, followed on the afternoon of October 12 by a green discolouration of seawater, strong bubbling and degassing indicating the initial stage of submarine volcanic eruption at approximately 2 km off the coast of La Restinga, El Hierro. Soil gas 222Rn and 220Rn activities were continuously measured during the period of the recent volcanic unrest occurred at El Hierro, at two different geochemical stations, HIE02 and HIE03. Significant increases in soil 222Rn activity and 222Rn/220Rn ratio from the soil were observed at both stations prior the submarine eruption off the coast of El Hierro, showing the highest increases before the eruption onset and the occurrence of the strongest seismic event (M=4.6). A statistical analysis showed that the long-term trend of the filtered data corresponded closely to the seismic energy released during the volcanic unrest. The observed increases of 222Rn are related to the rock fracturing processes (seismic activity) and the magmatic CO2 outflow increase, as observed in HIE03 station. Under these results, we find that continuous soil radon studies are important for evaluating the volcanic activity of El Hierro and they demonstrate the potential of applying continuous monitoring of soil radon to improve and optimize the detection of early warning signals of future

  4. Origin and significance of the 2011 El Hierro xeno-pumice

    NASA Astrophysics Data System (ADS)

    Zaczek-Pedroza, Kirsten; Troll, Valentin R.; Deegan, Frances M.; Meade, Fiona C.; Burchardt, Steffi; Carracedo, Juan C.; Klügel, Andreas; Harris, Chris; Wiesmaier, Sebastian; Berg, Sylvia E.; Barker, Abigail K.

    2014-05-01

    During the first week of the 2011/2012 submarine eruption off El Hierro (Canary Islands), peculiar light-coloured pumiceous rocks (xeno-pumice) were found floating on the sea. The appearance of these rocks led to a potentially inappropriate response from the authorities, because the rocks were viewed as likely indicators of high-silica magma and possible explosive eruptive behaviour. However, the eruption remained a relatively minor and dominantly effusive event and the origin and significance of these peculiar xeno-pumice rocks for volcanic monitoring remains unresolved. Three contrasting models have been put forward, describing them as: a) recycled hydrothermally altered felsic magmatic rocks (Meletlidis et al., 2012, Geophys. Res. Lett., 39:L17302), b) sediment-contaminated high-silica magma (Sigmarsson et al., 2013, Contrib. Mineral. Petrol., 165:601-622) or c) frothy xenoliths from pre-island sedimentary strata that were melted while immersed in magma (Troll et al., 2012, Solid Earth, 3:97-110). Here, we combine the three available datasets to assess the origin of El Hierro xeno-pumice in the light of texture, mineralogy, major and trace element composition, and oxygen isotope characteristics in order to discuss their significance. We note that: 1) Sedimentary relicts occur frequently in xeno-pumice samples with occasionally observed relict bedding. 2) Vesicle sizes are extremely variable, which documents multiple degassing events. The vesicles are biggest especially close to sedimentary relicts, likely the result of a complex mix of minerals and porewaters originally present. 3) The mineral assemblage of xeno-pumice includes quartz, smectite, illite, wollastonite, jasper and mica (XRD) and is akin to marine sedimentary rocks in the region (Hoernle, 1998, J. Petrol.,39:859-880; Robertson & Stillman, 1979, J. Geol. Soc., 136:47 -60; Aparicio et al., 2006, Geol. Mag. 143:181 -193). 4) CIPW norms calculated from xeno-pumice major element compositions show the

  5. Psychological aspects in a volcanic crisis: El Hierro Island eruption (October, 2011).

    NASA Astrophysics Data System (ADS)

    Lopez, P.; Llinares, A.; Garcia, A.; Marrero, J. M.; Ortiz, R.

    2012-04-01

    The recent eruption on the El Hierro Island (Canary Islands, Spain) has shown that Psychology plays an important role in the emergence management of a natural phenomenon. However, Psychology continues to have no social coverage it deserves in the mitigation of the effects before, during and after the occurrence of a natural phenomenon. Keep in mind that an unresolved psychological problem involves an individual and collective mismatch may become unrecoverable. The population of El Hierro has been under a state of alert since July 2011, when seismic activity begins, until the occurrence of submarine eruption in October 2011 that is held for more than three months. During this period the inhabitants of the small island have gone through different emotional states ranging from confusion to disappointment. A volcanic eruption occurs not unexpectedly, allowing to have a time of preparation / action before the disaster. From the psychological point of view people from El Hierro Island have responded to different stages of the same natural process. Although the island of El Hierro is of volcanic origin, the population has no historical memory since the last eruption occurred in 1793. Therefore, the educational system does not adequately address the formation in volcanic risk. As a result people feel embarrassment when the seismovolcanic crisis begins, although no earthquakes felt. As an intermediate stage, when the earthquakes are felt by the population, scientists and operational Emergency Plan care to inform and prepare actions in case of a possible eruption. The population feel safe despite the concerns expressed by not knowing where, how and when the eruption will occur. Once started the submarine eruption, taking into account that all the actions (evacuation, relocation, etc.) have worked well and that both their basic needs and security are covered there are new states of mind. These new emotional states ranging from disenchantment with the phenomenology of the

  6. Geochronological constraints on the evolution of El Hierro (Canary Islands)

    NASA Astrophysics Data System (ADS)

    Becerril, Laura; Ubide, Teresa; Sudo, Masafumi; Martí, Joan; Galindo, Inés; Galé, Carlos; Morales, Jose María; Yepes, Jorge; Lago, Marceliano

    2016-01-01

    New age data have been obtained to time constrain the recent Quaternary volcanism of El Hierro (Canary Islands) and to estimate its recurrence rate. We have carried out 40Ar/39Ar geochronology on samples spanning the entire volcanostratigraphic sequence of the island and 14C geochronology on the most recent eruption on the northeast rift of the island: 2280 ± 30 yr BP. We combine the new absolute data with a revision of published ages onshore, some of which were identified through geomorphological criteria (relative data). We present a revised and updated chronology of volcanism for the last 33 ka that we use to estimate the maximum eruptive recurrence of the island. The number of events per year determined is 9.7 × 10-4 for the emerged part of the island, which means that, as a minimum, one eruption has occurred approximately every 1000 years. This highlights the need of more geochronological data to better constrain the eruptive recurrence of El Hierro.

  7. Early signs of geodynamic activity before the 2011-2012 El Hierro eruption

    NASA Astrophysics Data System (ADS)

    López, Carmen; García-Cañada, Laura; Martí, Joan; Domínguez Cerdeña, Itahiza

    2017-04-01

    The potential relation between mantle plume dynamics, regional tectonics and eruptive activity in the Canary Islands has not been studied yet through the analysis of long-time series of geophysical observational data. The existence of highly reliable seismic and GNSS data has enabled us to study from 1996 to 2014 the geodynamic evolution of the North Atlantic Azores-Gibraltar region and its relationship with recent volcanic activity in El Hierro (Canary Islands, Spain). We compiled a new and unified regional seismic catalog and used long time-series of surface displacements recorded by permanent GNSS stations in the region. A regional- and local-scale analysis based on these data enabled us to identify signs of anomalous tectonic activity from 2003 onwards, whose intensity increased in 2007 and finally accelerated three months before the onset of the volcanic eruption on El Hierro in October 2011. This activity includes a regional extension and an uplift process that affects the southern Iberian Peninsula, NW Africa, and the Canary Islands. We interpret these observations as early signs of the geodynamic activity, which led to El Hierro eruption and the subsequent episodes of magma intrusion. Results point to the significant contribution of the mantle plume dynamics (i.e. external forces) in this renewed volcanic activity in the Canary Islands and emphasize the role of mantle dynamics in controlling regional tectonics.

  8. Melt inclusion study of the most recent basanites from El Hierro and Lanzarote, Canary Islands

    NASA Astrophysics Data System (ADS)

    Gomez-Ulla, Alejandra; Sigmarsson, Olgeir; Huertas, Maria Jose; Ancochea, Eumenio

    2015-04-01

    The latest eruptions of both Lanzarote (one of the oldest and easternmost of the Canary Island archipelago) and El Hierro (the youngest and westernmost) produced basanite lavas. Major, volatile and trace element concentrations of melt inclusion (MI) hosted in olivine for both eruptions have been analysed. The basanites display primitive mantle normalized trace element spectra suggesting a magma source largely composed of recycled oceanic crust. In addition, beneath Lanzarote an interaction with a carbonatitic fluid phase or metasome would explain eccentric Ba/U and other trace element ratios. Contribution of carbonatitic component would readily account for extremely volatile-rich (Cl, F, S) MI from Lanzarote (Cl=1577-2500 ppm) whereas the maximum for El Hierro is 1080 ppm. The submarine character of the 2011-12 eruption off El Hierro appears to have affected the degassing behavior, whereas estimated sulfur emission to the atmosphere during the historical Lanzarote eruptions are amongst the highest observed so far. An estimated magma volume (VDRE) of 0.02 km3 yields atmospheric mass loading of 0.2 Mt SO2 from the 1824 Lanzarote eruption. Scaling the volume of the 1824 Lanzarote eruption to that of the previous Timanfaya eruption (1730-6; 5 km3) results in estimated 12 Mt SO2, an atmospheric mass loading only outnumbered by the historical Laki and Eldgjá eruptions in Iceland. The significantly greater volatile budget of basanites from Lanzarote compared to El Hierro is thus controlled by more fertile source composition closer to the African continent.

  9. Early signs of geodynamic activity before the 2011-2012 El Hierro eruption

    NASA Astrophysics Data System (ADS)

    López, Carmen; García-Cañada, Laura; Martí, Joan; Domínguez Cerdeña, Itahiza

    2017-02-01

    The potential relation between mantle plume dynamics, regional tectonics and eruptive activity in the Canary Islands has not been studied yet through the analysis of long-time series of geophysical observational data. The existence of highly reliable seismic and geodetic data has enabled us to study from 1996 to 2014 the geodynamic evolution of the North Atlantic Azores-Gibraltar region (including the NW African margin) and its relationship with recent volcanic activity in El Hierro (Canary Islands). We compiled a new and unified regional seismic catalog and used long time-series of digital 3D surface displacements recorded by permanent GPS stations in the region. A joint regional- and local-scale analysis based on these data enabled us to identify signs of anomalous tectonic activity from 2003 onwards, whose intensity increased in 2007 and finally accelerated three months before the onset of the volcanic eruption on El Hierro in October 2011. Activity included the occurrence of regional extension and an uplift process affecting the southern Iberian Peninsula, NW Africa, and the Canary Islands. We interpret these observations as early signs of the geodynamic activity, which led to El Hierro eruption and the subsequent episodes of magma intrusion. Results point to the significant contribution of the mantle plume dynamics (i.e. external forces) in this renewed volcanic activity in the Canary Islands and emphasize the role of mantle dynamics in controlling regional tectonics.

  10. From 3D to 4D seismic tomography at El Hierro Island (Canary Islands, Spain)

    NASA Astrophysics Data System (ADS)

    Garcia-Yeguas, A.; Koulakov, I.; Jakovlev, A.; Ibáñez, J. M.

    2012-04-01

    In this work we are going to show the advantages of a dynamic tomography 4D, versus a static image 3D related with a volcanic reactivation and eruption at El Hierro island (Canary Islands, Spain). In this process a high number of earthquakes before and during the eruptive processes have been registered. We are going to show a 3D image as an average of the velocity structure and then the characteristics and physical properties on the medium, including the presence or not of magma. This image will be complemented with its evolution along the time, observing its volcanic dynamic and its influence over the medium properties, including its power as an important element on early warnings protocols. After more than forty years of quiet at Canary Islands, since 1971 with Teneguía eruption at La Palma Island, and more than 200 years on El Hierro Island (The last eruption known at El Hierro took place in 1793, volcán de Lomo Negro), on 19th July on 2011 the Spanish seismic national network, administered by IGN (Instituto Geográfico Nacional), detected an increase of local seismic activity below El Hierro island (Canary Islands, Spain). Since this moment an intense swarm took place, with more than 11000 events, until 11th December, with magnitudes (MLg) from 0.2 to 4.4. In this period two eruptive processes have been declared in front of the South coast of El Hierro island, and they have not finished yet. This seismic swarm has allowed carrying out a 3D seismic tomography, using P and S waves traveltimes. It has showed a low velocity from the North to the South. On the other hand, we have performed a 4D seismic tomography, taking the events occurred at different intervals of time. We can observe the evolution of the negative anomaly along the time, from the North to the South, where has taken place La Restinga submarine eruption. 4D seismic tomography is an innovative and powerful tool able to show the evolution in time of a volcanic process.

  11. El Hierro's floating stones as messengers of crust-magma interaction at depth

    NASA Astrophysics Data System (ADS)

    Burchardt, S.; Troll, V. R.; Schmeling, H.; Koyi, H.; Blythe, L. S.; Longpré, M. A.; Deegan, F. M.

    2012-04-01

    During the early stages of the submarine eruption that started on October 10 2011 south of El Hierro, Canary Islands, Spain, peculiar eruption products were found floating on the sea surface. These centimetre- to decimetre-sized "bombs" have been termed "restingolites" after the nearby village La Restinga and consist of a basaltic rind and a white to light grey core that resembles pumice in texture. According to Troll et al. (2011; see also Troll et al. EGU 2012 Abstracts), this material consists of a glassy matrix hosting extensive vesicle networks, which results in extremely low densities allowing these rocks to float on sea water. Mineralogical and geochemical analyses reveal that the "restingolites" originate from the sedimentary rocks (sand-, silt-, and mudstones) that form layer 1 of the oceanic crust beneath El Hierro. During the onset and early stages of the eruption, magma ponded at the base of this sedimentary sequence, breaking its way through the sedimentary rocks to the ocean floor. The textures of the "restingolites" reveal that crust-magma interaction during fragmentation and transport of the xenoliths involved rapid partial melting and volatile exsolution. Xenoliths strikingly similar to those from El Hierro are known from eruptions on other Canary Islands (e.g. La Palma, Gran Canaria, and Lanzarote). In fact, they resemble in texture xenoliths of various protoliths from volcanic areas worldwide (e.g. Krakatao, Indonesia, Cerro Quemado, Guatemala, Laacher See, Germany). This indicates that the process of partial melting and volatile exsolution, which the "restingolites" bear witness of, is probably occurring frequently during shallow crustal magma emplacement. Thermomechanical numerical models of the effect of the density decrease associated with the formation of vesicle networks in partially molten xenoliths show that xenoliths of crustal rocks initially sink in a magma chamber, but may start to float to the chamber roof once they start to heat up

  12. Magmatic sill intrusions beneath El Hierro Island following the 2011-2012 submarine eruption

    NASA Astrophysics Data System (ADS)

    Benito-Saz, María Á.; Sigmundsson, Freysteinn; Parks, Michelle M.; García-Cañada, Laura; Domínguez Cerdeña, Itahiza

    2016-04-01

    El Hierro, the most southwestern island of Canary Islands, Spain, is a volcano rising from around 3600 m above the ocean floor and up to of 1500 m above sea level. A submarine eruption occurred off the coast of El Hierro in 2011-2012, which was the only confirmed eruption in the last ~ 600 years. Activity continued after the end of the eruption with six magmatic intrusions occurring between 2012-2014. Each of these intrusions was characterized by hundreds of earthquakes and 3-19 centimeters of observed ground deformation. Ground displacements at ten continuous GPS sites were initially inverted to determine the optimal source parameters (location, geometry, volume/pressure change) that best define these intrusions from a geodetic point of view. Each intrusive period appears to be associated with the formation of a separate sill, with inferred volumes between 0.02 - 0.3 km3. SAR images from the Canadian RADARSAT-2 satellite and the Italian Space Agency COSMO-SkyMed constellation have been used to produce high-resolution detailed maps of line-of-sight displacements for each of these intrusions. These data have been combined with the continuous GPS observations and a joint inversion undertaken to gain further constraints on the optimal source parameters for each of these separate intrusive events. The recorded activity helps to understand how an oceanic intraplate volcanic island grows through repeated sill intrusions; well documented by seismic, GPS and InSAR observations in the case of the El Hierro activity.

  13. Volcanic Alert System (VAS) developed during the (2011-2013) El Hierro (Canary Islands) volcanic process

    NASA Astrophysics Data System (ADS)

    Ortiz, Ramon; Berrocoso, Manuel; Marrero, Jose Manuel; Fernandez-Ros, Alberto; Prates, Gonçalo; De la Cruz-Reyna, Servando; Garcia, Alicia

    2014-05-01

    In volcanic areas with long repose periods (as El Hierro), recently installed monitoring networks offer no instrumental record of past eruptions nor experience in handling a volcanic crisis. Both conditions, uncertainty and inexperience, contribute to make the communication of hazard more difficult. In fact, in the initial phases of the unrest at El Hierro, the perception of volcanic risk was somewhat distorted, as even relatively low volcanic hazards caused a high political impact. The need of a Volcanic Alert System became then evident. In general, the Volcanic Alert System is comprised of the monitoring network, the software tools for the analysis of the observables, the management of the Volcanic Activity Level, and the assessment of the threat. The Volcanic Alert System presented here places special emphasis on phenomena associated to moderate eruptions, as well as on volcano-tectonic earthquakes and landslides, which in some cases, as in El Hierro, may be more destructive than an eruption itself. As part of the Volcanic Alert System, we introduce here the Volcanic Activity Level which continuously applies a routine analysis of monitoring data (particularly seismic and deformation data) to detect data trend changes or monitoring network failures. The data trend changes are quantified according to the Failure Forecast Method (FFM). When data changes and/or malfunctions are detected, by an automated watchdog, warnings are automatically issued to the Monitoring Scientific Team. Changes in the data patterns are then translated by the Monitoring Scientific Team into a simple Volcanic Activity Level, that is easy to use and understand by the scientists and technicians in charge for the technical management of the unrest. The main feature of the Volcanic Activity Level is its objectivity, as it does not depend on expert opinions, which are left to the Scientific Committee, and its capabilities for early detection of precursors. As a consequence of the El Hierro

  14. Structural interpretation of El Hierro (Canary Islands) rifts system from gravity inversion modelling

    NASA Astrophysics Data System (ADS)

    Sainz-Maza, S.; Montesinos, F. G.; Martí, J.; Arnoso, J.; Calvo, M.; Borreguero, A.

    2017-08-01

    Recent volcanism in El Hierro Island is mostly concentrated along three elongated and narrow zones which converge at the center of the island. These zones with extensive volcanism have been identified as rift zones. The presence of similar structures is common in many volcanic oceanic islands, so understanding their origin, dynamics and structure is important to conduct hazard assessment in such environments. There is still not consensus on the origin of the El Hierro rift zones, having been associated with mantle uplift or interpreted as resulting from gravitational spreading and flank instability. To further understand the internal structure and origin of the El Hierro rift systems, starting from the previous gravity studies, we developed a new 3D gravity inversion model for its shallower layers, gathering a detailed picture of this part of the island, which has permitted a new interpretation about these rifts. Previous models already identified a main central magma accumulation zone and several shallower high density bodies. The new model allows a better resolution of the pathways that connect both levels and the surface. Our results do not point to any correspondence between the upper parts of these pathways and the rift identified at the surface. Non-clear evidence of progression toward deeper parts into the volcanic system is shown, so we interpret them as very shallow structures, probably originated by local extensional stresses derived from gravitational loading and flank instability, which are used to facilitate the lateral transport of magma when it arrives close to the surface.

  15. Monitoring diffuse degassing in monogentic volcanic field during magmatic reactivation: the case of El Hierro (Canary Islands, Spain)

    NASA Astrophysics Data System (ADS)

    Morales-Ocaña, C.; Feldman, R. C.; Pointer, Z. R.; Rodríguez, F.; Asensio-Ramos, M.; Melián, G.; Padrón, E.; Hernández, P. A.; Pérez, N. M.

    2017-12-01

    El Hierro (278 km2), the younger, smallest and westernmost island of the Canarian archipelago, is a 5-km-high edifice constructed by rapid constructive and destructive processes in 1.12 Ma, with a truncated trihedron shape and three convergent ridges of volcanic cones. It experienced a submarine eruption from 12 October, 2011 and 5 March 2012, off its southern coast that was the first one to be monitored from the beginning in the Canary Islands. As no visible emanations occur at the surface environment of El Hierro, diffuse degassing studies have become a useful geochemical tool to monitor the volcanic activity in this volcanic island. Diffuse CO2 emission has been monitored at El Hierro Island since 1998 in a yearly basis, with much higher frequency in the period 2011-2012. At each survey, about 600 sampling sites were selected to obtain a homogeneous distribution. Measurements of soil CO2 efflux were performed in situ following the accumulation chamber method. During pre-eruptive and eruptive periods, the diffuse CO2 emission released by the whole island experienced significant increases before the onset of the submarine eruption and the most energetic seismic events of the volcanic-seismic unrest (Melián et al., 2014. J. Geophys. Res. Solid Earth, 119, 6976-6991). The soil CO2 efflux values of the 2017 survey ranged from non-detectable to 53.1 g m-2 d-1. Statistical-graphical analysis of the data show two different geochemical populations; background (B) and peak (P) represented by 77.6% and 22.4% of the total data, respectively, with geometric means of 1.8 and 9.2 g m-2 d-1, respectively. Most of the area showed B values while the P values were mainly observed at the interception center of the three convergent ridges and the north of the island. To estimate the diffuse CO2 emission for the 2017 survey, we ran about 100 sGs simulations. The estimated 2017 diffuse CO2 output released to atmosphere by El Hierro was at 1,150 ± 42 t d-1, value higher than the

  16. Forecasting the 2011 El Hierro submarine eruption (Canary Islands) on the basis of soil He degassing surveys

    NASA Astrophysics Data System (ADS)

    Padrón, E.; Pérez, N. M.; Hernández, P. A.; Melián, G. V.; Padilla, G. D.; Barrancos, J.; Dionis, S.; Rodríguez, F.; Nolasco, D.; Calvo, D.; Hernández, I.; Peraza, M. D.

    2012-04-01

    El Hierro Island is the southwesternmost and the youngest island of the Canary archipelago. Since 16 July, an anomalous seismicity at El Hierro island was recorded by IGN seismic network. After the occurrence of more than 10,000 seismic events, volcanic tremor was recorded since 05:15 of the October 10, by all of the seismic stations on the island, with highest amplitudes recorded in the southernmost station. During the afternoon of 12 October a large light-green coloured area was observed in the sea to the souht of La Restinga village (at the southernmost part of El Hierro island), suggesting the existence of a submarine eruption. Since October 12, frequent episodes of, turbulent gas emission and foaming, and the appearance of steamy lava fragments has been observed on the sea surface. As part of the volcanic surveillance of the island, the Instituto Volcanologico de Canarias (INVOLCAN) geochemical monitoring program is carrying out diffuse helium surveys on the surface environment of El Hierro (soil atmosphere). This nobel gas has been investigated because it has been considered an almost ideal geochemical indicator because it is chemically inert, physically stable, nonbiogenic, sparingly soluble in water under ambient conditions and almost non-adsorbable. At each survey, 600 sampling sites covering the whole island and following an homogeneous distribution are selected for helium measurements in the soil gases, The helium concentration gradients with respect to its value on air (5.24 ppm) allow us to estimate a pure diffusive emission rate of helium throughout the island. The first survey was carried out on the summer of 2003, when the island was on a quiescence period. At this survey, the amount of helium released by the volcanic system of El Hierro was estimated in 6 kg/d. Since the beginning of the seismic unrest, 13 helium emission surveys have been carried out. The helium emission rate has shown an excellent agreement with the evolution of the volcanic

  17. Study of the thermohygrometric conditions of Juniperus turbinata habitat in the island of El Hierro (Canary Islands)

    NASA Astrophysics Data System (ADS)

    Salva-Catarineu, Montserrat; Salvador-Franch, Ferran; López-Bustins, Joan Albert; Padrón-Padrón, Perdro A.; Cortés-Lucas, Amparo

    2015-04-01

    The biggest population of Juniperus turbinata throughout the Canary Islands is located in the island of El Hierro. The current extent of juniper woodlands is very small compared with the potential distribution due to heavy exploitation for centuries. Nowadays, the recovery of its natural habitat has such a high environmental and scenic interest since this is a protected species in Europe; however, an improved understanding of the environmental factors that help or limit its recovery is indispensable. Under the JUNITUR project the populations of juniper woodlands in El Hierro are being studied, which are subjected to highly different environments. These environments are mainly determined by their altitude and exposure to NE trade winds. The main objective of this study is to compare the thermohygrometric conditions of three juniper woodlands, located at different altitude and orientation in El Hierro, which present different recovery rates. We are currently using air sensor data loggers fixed to tree branches for recording hourly temperature and humidity data in the three study areas. For this preliminary approach, we analyse daily data of two annual cycles (from September 2012 to August 2014). Our first results show similar thermohygrometric annual cycles among the three study areas. The largest differences are detected in winter temperature and summer humidity between the north (to windward) and south (to leeward) faces of the island. The juniper woodland with a highest recovery rate shows the most extreme temperature conditions in both winter and summer seasons. This last juniper woodland is located leeward to trade winds at 996 m a.s.l. In general terms, the results of this research project might contribute to the knowledge of the juniper bioclimatology in the westernmost of the Canary Islands. Key words: bioclimatology, El Hierro, habitat, Juniperus turbinata, protected species

  18. Soil gas 222Rn and volcanic activity at El Hierro (Canary Islands) before and after the 2011 submarine eruption

    NASA Astrophysics Data System (ADS)

    Padilla, G.; Hernández, P. A.; Padrón, E.; Barrancos, J.; Melián, G.; Dionis, S.; Rodríguez, F.; Nolasco, D.; Calvo, D.; Hernández, I.; Pereza, M. D.; Pérez, N. M.

    2012-04-01

    El Hierro (278 km2) is the southwesternmost island of the Canarian archipelago. From June 19, 2011 to January 2012, more than 11,950 seismic events have been detected by the seismic network of IGN. On 10 October 2011 the earthquake swarm changed its behaviour and produced a harmonic tremor due to magma movement, indicating that a submarine eruption located at 2 km south of La Restinga had started which is still in progress. Since 2003, the ITER Environmental Research Division now integrated in the Instituto Volcanológico de Canarias, INVOLCAN, has regularly performed soil gas surveys at El Hierro as a geochemical tool for volcanic surveillance. Among the investigated gases, soil gas radon (222Rn) and thoron (220Rn) have played a special attention. Both gases are characterized to ascend towards the surface mainly through cracks or faults via diffusion or advection, mechanisms dependent of both soil porosity and permeability, which in turn vary as a function of the stress/strain changes at depth. Years before the starts of the volcanic-seismic crisis on July 17, 2011, a volcanic multidisciplinary surveillance program was implemented at El Hierro including discrete and continuous measurements of 222Rn and 220Rn. Two soil gas 222Rn surveys had been carried out at El Hierro in 2003 and 2011, and four continuous geochemical monitoring stations for 222Rn and 220Rn measurements had been installed (HIE02, HIE03, HIE04 and HIE08). Soil gas 222Rn surveys were carried out at the surface environment of El Hierro after selecting 600 sampling observation sites (about 40 cm depth). Geochemical stations measure 222Rn and 220Rn activities by pumping the gas from a PVC pipe inserted 1m in the ground and thermally isolated. The results of the 2003 and 2011 soil gas 222Rn surveys show clearly a relatively higher observed 222Rn activities in the surface environment on 2011 than those observed on 2003 when no anomalous seismicity were taking place beneath El Hierro. The observed

  19. Precursory diffuse CO2 emission signature of the 2011 El Hierro submarine eruption, Canary Islands

    NASA Astrophysics Data System (ADS)

    Pérez, N. M.; Padilla, G. D.; Padrón, E.; Hernández, P. A.; Melián, G. V.; Barrancos, J.; Dionis, S.; Rodríguez, F.; Nolasco, D.; Calvo, D.; Hernández, I.; Peraza, M. D.

    2012-04-01

    El Hierro is the youngest and southernmost island of the Canarian archipelago and represents the summit of a volcanic shield elevating from the surrounding seafloor at depth of 4000 m to up to 1501 m above sea level. The island is believed to be near the present hotspot location in the Canaries with the oldest subaerial rocks dated at 1.12 Ma. The subaerial parts of the El Hierro rift zones (NE, NW and S Ridges) are characterized by tightly aligned dyke complexes with clusters of cinder cones as their surface expressions. Since 16 July, an anomalous seismicity at El Hierro Island was recorded by IGN seismic network. Volcanic tremor started at 05:15 on 10 October, followed on the afternoon of 12 October by a green discolouration of seawater, strong bubbling and degassing, and abundant bombs on a decimetre scale found floating on the ocean surface offshore, southwest of La Restinga village, indicating the occurrence of a submarine volcanic eruption at approximately 2 km far the coast line of La Restinga. Further episodes have occurred during November, December 2011 and January 2012, with turbulent water, foam rings, and volcanic material again reaching the sea surface. In order to improve the volcanic surveillance program of El Hierro Island and to provide a multidisciplinary approach, a continuous geochemical station to measure CO2 efflux was installed on September 2003 in Llanos de Guillen, the interception center of the three volcanic-rift zones of the island, with the aim of detecting changes in the diffuse emission of CO2 related to the seismic or volcanic activity. The station measures on an hourly basis the CO2 and H2S efflux, the CO2 and H2S air concentrations, the soil water content and temperature and the atmospheric parameters: wind speed and direction, air temperature and humidity and barometric pressure. The meteorological parameters together with the air CO2 concentration are measured 1 m above the ground and the soil water content and soil temperature

  20. Analysis of surface deformation during the eruptive process of El Hierro Island (Canary Islands, Spain): Detection, Evolution and Forecasting.

    NASA Astrophysics Data System (ADS)

    Berrocoso, M.; Fernandez-Ros, A.; Prates, G.; Martin, M.; Hurtado, R.; Pereda, J.; Garcia, M. J.; Garcia-Cañada, L.; Ortiz, R.; Garcia, A.

    2012-04-01

    The surface deformation has been an essential parameter for the onset and evolution of the eruptive process of the island of El Hierro (October 2011) as well as for forecasting changes in seismic and volcanic activity during the crisis period. From GNSS-GPS observations the reactivation is early detected by analizing the change in the deformation of the El Hierro Island regional geodynamics. It is found that the surface deformation changes are detected before the occurrence of seismic activity using the station FRON (GRAFCAN). The evolution of the process has been studied by the analysis of time series of topocentric coordinates and the variation of the distance between stations on the island of El Hierro (GRAFCAN station;IGN network; and UCA-CSIC points) and LPAL-IGS station on the island of La Palma. In this work the main methodologies and their results are shown: •The location (and its changes) of the litospheric pressure source obtained by applying the Mogi model. •Kalman filtering technique for high frequency time series, used to make the forecasts issued for volcanic emergency management. •Correlations between deformation of the different GPS stations and their relationship with seismovolcanic settings.

  1. Influence of the submarine volcanic eruption off El Hierro (Canary Islands) on the mesopelagic cephalopod's metal content.

    PubMed

    Lozano-Bilbao, Enrique; Gutiérrez, Ángel José; Hardisson, Arturo; Rubio, Carmen; González-Weller, Dailos; Aguilar, Natacha; Escánez, Alejandro; Espinosa, José María; Canales, Paula; Lozano, Gonzalo

    2018-04-01

    This work investigates whether a submarine volcanic eruption off El Hierro (Canary Islands) in October 2011 influenced the metal contents of two deep water cephalopod species: Abraliopsis morisii and Pyroteuthis margaritifera. This was assessed by comparing metal contents in specimens collected off the island of El Hierro and in the neighbouring islands of La Palma and Tenerife during an experimental deep water fishing trip. The concentration of 20 heavy metals was analyzed in 180 specimens of A. morisii and P. margaritifera collected around the three islands to test for inter-island differences for each species and metal. While both species showed geographical differences in metal concentrations, the main finding was that A. morisii could be a bioindicator species for metals such as Li, Sr and Ca. Copyright © 2017 Elsevier Ltd. All rights reserved.

  2. Driving magma to the surface: The 2011-2012 El Hierro Volcanic Eruption

    NASA Astrophysics Data System (ADS)

    López, Carmen; Benito-Saz, Maria A.; Martí, Joan; del-Fresno, Carmen; García-Cañada, Laura; Albert, Helena; Lamolda, Héctor

    2017-08-01

    We reanalyzed the seismic and deformation data corresponding to the preeruptive unrest on El Hierro (Canary Islands) in 2011. We considered new information about the internal structure of the island. We updated the seismic catalog to estimate the full evolution of the released seismic energy and demonstrate the importance of nonlocated earthquakes. Using seismic data and GPS displacements, we characterized the shear-tensile type of the predominant fracturing and modeled the strain and stress fields for different time periods. This enabled us to identify a prolonged first phase characterized by hydraulic tensile fracturing, which we interpret as being related to the emplacement of new magma below the volcanic edifice on El Hierro. This was followed by postinjection unidirectional migration, probably controlled by the stress field and the distribution of the structural discontinuities. We identified the effects of energetic magmatic pulses occurring a few days before the eruption that induced shear seismicity on preexisting faults within the volcano and raised the Coulomb stress over the whole crust. We suggest that these magmatic pulses reflect the crossing of the Moho discontinuity, as well as changes in the path geometry of the dyke migration toward the surface. The final phase involved magma ascent through a prefractured crust.

  3. Evidence from acoustic imaging for submarine volcanic activity in 2012 off the west coast of El Hierro (Canary Islands, Spain)

    NASA Astrophysics Data System (ADS)

    Pérez, Nemesio M.; Somoza, Luis; Hernández, Pedro A.; de Vallejo, Luis González; León, Ricardo; Sagiya, Takeshi; Biain, Ander; González, Francisco J.; Medialdea, Teresa; Barrancos, José; Ibáñez, Jesús; Sumino, Hirochika; Nogami, Kenji; Romero, Carmen

    2014-12-01

    We report precursory geophysical, geodetic, and geochemical signatures of a new submarine volcanic activity observed off the western coast of El Hierro, Canary Islands. Submarine manifestation of this activity has been revealed through acoustic imaging of submarine plumes detected on the 20-kHz chirp parasound subbottom profiler (TOPAS PS18) mounted aboard the Spanish RV Hespérides on June 28, 2012. Five distinct "filament-shaped" acoustic plumes emanating from the flanks of mounds have been recognized at water depth between 64 and 88 m on a submarine platform located NW El Hierro. These plumes were well imaged on TOPAS profiles as "flares" of high acoustic contrast of impedance within the water column. Moreover, visible plumes composed of white rafts floating on the sea surface and sourcing from the location of the submarine plumes were reported by aerial photographs on July 3, 2012, 5 days after acoustic plumes were recorded. In addition, several geophysical and geochemical data support the fact that these submarine vents were preceded by several precursory signatures: (i) a sharp increase of the seismic energy release and the number of daily earthquakes of magnitude ≥2.5 on June 25, 2012, (ii) significant vertical and horizontal displacements observed at the Canary Islands GPS network (Nagoya University-ITER-GRAFCAN) with uplifts up to 3 cm from June 25 to 26, 2012, (iii) an anomalous increase of the soil gas radon activity, from the end of April until the beginning of June reaching peak values of 2.7 kBq/m3 on June 3, 2012, and (iv) observed positive peak in the air-corrected value of 3He/4He ratio monitored in ground waters (8.5 atmospheric 3He/4He ratio ( R A)) at the northwestern El Hierro on June 16, 2012. Combining these submarine and subaerial information, we suggest these plumes are the consequence of submarine vents exhaling volcanic gas mixed with fine ash as consequence of an event of rapid rise of volatile-rich magma beneath the NW submarine ridge

  4. Physico-chemical changes of the ground waters related to the 2011 El Hierro magmatic reactivation

    NASA Astrophysics Data System (ADS)

    Dionis, S.; Melián, G.; Padrón, E.; Padilla, G.; Nolasco, D.; Rodríguez, F.; Hernández, I.; Peraza, D.; Barrancos, J.; Hernández, P.; Calvo, D.; Pérez, N.

    2012-04-01

    The island of El Hierro (278 Km2), is the smallest, the southwesternmost and the youngest island (˜1.12 My) of the Canarian archipelago. The main geological characteristics of El Hierro consist on the presence of three convergent ridges of volcanic cones on a truncated trihedron shape and giant landslides between the three rift zones, being the most recent El Golfo on the northwest flank of the island. On July 2011 an anomalous seismic activity at Hierro Island started and suggested the initial stage of a volcanic unrest in the volcanic system. On October 10, after the occurrence of more than 10,000 earthquakes, a submarine eruption started. Evidences of this submarine volcanic eruption were visible on the sea surface to the south of La Restinga village, at the south of the island, in the form of large light-green coloured area, turbulent gas emission and the appearance of steamy volcanic fragments three days later. As part of its volcanic surveillance activities, the Instituto Volcanologico de Canarias (INVOLCAN) started a hydrogeochemical monitoring program on August 2011 in order to evaluate the temporal evolution of several physico-chemical parameters of the ground water system of El Hierro. Four observation sites were selected: three wells on the north of the island, where the seismic activity was located at the beginning of the volcano-seismic unrest (SIMO, FRON and PADO) and one horizontal well (gallery) in the south (TACO). Ground water sampling is being regularly collected, three times per week, at each observation site, and in-situ measurements of pH, conductivity and temperature measurements are performed. After 6 month of monitoring, no significant changes have been observed on pH and temperature measurements from all the observation sites. However, clear sharp decrease of conductivity was observed at SIMO on October 10 when the seismic tremor started. In addition, the strongest conductivity decrease pattern was observed later on at SIMO and PADO on

  5. Xenopumice erupted on 15 October 2011 offshore of El Hierro (Canary Islands): a subvolcanic snapshot of magmatic, hydrothermal and pyrometamorphic processes

    NASA Astrophysics Data System (ADS)

    Del Moro, S.; Di Roberto, A.; Meletlidis, S.; Pompilio, M.; Bertagnini, A.; Agostini, S.; Ridolfi, F.; Renzulli, A.

    2015-06-01

    On 15 October 2011, a submarine eruption offshore of El Hierro Island gave rise to floating volcanic products, known as xenopumices, i.e., pumiceous xenoliths partly mingled and coated with the juvenile basanitic magma. Over the last few years, no consensus in the scientific community in explaining the origin of these products has been reached. In order to better understand the formation of xenopumice, we present a textural, mineralogical, and geochemical study of the possible magmatic, hydrothermal, and pyrometamorphic processes, which usually operate in the plumbing systems of active volcanoes. We carried out a comprehensive SEM investigation and Sr-Nd-Pb isotope analyses on some samples representative of three different xenopumice facies. All the data were compared with previous studies, new data for El Hierro extrusives and a literature dataset of Canary Islands igneous and sedimentary rocks. In the investigated xenopumices, we emphasize the presence of restitic magmatic phases as well as crystallization of minerals (mainly olivine + pyroxene + magnetite aggregates) as pseudomorphs after pre-existing mafic phenocrysts, providing evidence of pyrometamorphism induced by the high-T juvenile basanitic magma. In addition, we identify veins consisting of zircon + REE-oxides + mullite associated with Si-rich glass and hydrothermal quartz, which indicate the fundamental role played by hydrothermal fluid circulation in the xenopumice protolith. The petrological data agree with a pre-syneruptive formation of the xenopumice, when El Hierro basanite magma intruded hydrothermally altered trachyandesite to trachyte rocks and triggered local partial melting. Therefore, the El Hierro xenopumice represents a snapshot of the transient processes at the magma-wall rock interface, which normally occurs in the feeding system of active volcanoes.

  6. Volcanic alert system (VAS) developed during the 2011-2014 El Hierro (Canary Islands) volcanic process

    NASA Astrophysics Data System (ADS)

    García, Alicia; Berrocoso, Manuel; Marrero, José M.; Fernández-Ros, Alberto; Prates, Gonçalo; De la Cruz-Reyna, Servando; Ortiz, Ramón

    2014-06-01

    The 2011 volcanic unrest at El Hierro Island illustrated the need for a Volcanic Alert System (VAS) specifically designed for the management of volcanic crises developing after long repose periods. The VAS comprises the monitoring network, the software tools for analysis of the monitoring parameters, the Volcanic Activity Level (VAL) management, and the assessment of hazard. The VAS presented here focuses on phenomena related to moderate eruptions, and on potentially destructive volcano-tectonic earthquakes and landslides. We introduce a set of new data analysis tools, aimed to detect data trend changes, as well as spurious signals related to instrumental failure. When data-trend changes and/or malfunctions are detected, a watchdog is triggered, issuing a watch-out warning (WOW) to the Monitoring Scientific Team (MST). The changes in data patterns are then translated by the MST into a VAL that is easy to use and understand by scientists, technicians, and decision-makers. Although the VAS was designed specifically for the unrest episodes at El Hierro, the methodologies may prove useful at other volcanic systems.

  7. Nannofossils in 2011 El Hierro eruptive products reinstate plume model for Canary Islands

    NASA Astrophysics Data System (ADS)

    Zaczek, Kirsten; Troll, Valentin R.; Cachao, Mario; Ferreira, Jorge; Deegan, Frances M.; Carracedo, Juan Carlos; Soler, Vicente; Meade, Fiona C.; Burchardt, Steffi

    2015-01-01

    The origin and life cycle of ocean islands have been debated since the early days of Geology. In the case of the Canary archipelago, its proximity to the Atlas orogen led to initial fracture-controlled models for island genesis, while later workers cited a Miocene-Quaternary east-west age-progression to support an underlying mantle-plume. The recent discovery of submarine Cretaceous volcanic rocks near the westernmost island of El Hierro now questions this systematic age-progression within the archipelago. If a mantle-plume is indeed responsible for the Canaries, the onshore volcanic age-progression should be complemented by progressively younger pre-island sedimentary strata towards the west, however, direct age constraints for the westernmost pre-island sediments are lacking. Here we report on new age data obtained from calcareous nannofossils in sedimentary xenoliths erupted during the 2011 El Hierro events, which date the sub-island sedimentary rocks to between late Cretaceous and Pliocene in age. This age-range includes substantially younger pre-volcanic sedimentary rocks than the Jurassic to Miocene strata known from the older eastern islands and now reinstate the mantle-plume hypothesis as the most plausible explanation for Canary volcanism. The recently discovered Cretaceous submarine volcanic rocks in the region are, in turn, part of an older, fracture-related tectonic episode.

  8. Nannofossils in 2011 El Hierro eruptive products reinstate plume model for Canary Islands.

    PubMed

    Zaczek, Kirsten; Troll, Valentin R; Cachao, Mario; Ferreira, Jorge; Deegan, Frances M; Carracedo, Juan Carlos; Soler, Vicente; Meade, Fiona C; Burchardt, Steffi

    2015-01-22

    The origin and life cycle of ocean islands have been debated since the early days of Geology. In the case of the Canary archipelago, its proximity to the Atlas orogen led to initial fracture-controlled models for island genesis, while later workers cited a Miocene-Quaternary east-west age-progression to support an underlying mantle-plume. The recent discovery of submarine Cretaceous volcanic rocks near the westernmost island of El Hierro now questions this systematic age-progression within the archipelago. If a mantle-plume is indeed responsible for the Canaries, the onshore volcanic age-progression should be complemented by progressively younger pre-island sedimentary strata towards the west, however, direct age constraints for the westernmost pre-island sediments are lacking. Here we report on new age data obtained from calcareous nannofossils in sedimentary xenoliths erupted during the 2011 El Hierro events, which date the sub-island sedimentary rocks to between late Cretaceous and Pliocene in age. This age-range includes substantially younger pre-volcanic sedimentary rocks than the Jurassic to Miocene strata known from the older eastern islands and now reinstate the mantle-plume hypothesis as the most plausible explanation for Canary volcanism. The recently discovered Cretaceous submarine volcanic rocks in the region are, in turn, part of an older, fracture-related tectonic episode.

  9. Heterogeneous vesiculation of 2011 El Hierro xeno-pumice revealed by X-ray computed microtomography

    NASA Astrophysics Data System (ADS)

    Berg, S. E.; Troll, V. R.; Deegan, F. M.; Burchardt, S.; Krumbholz, M.; Mancini, L.; Polacci, M.; Carracedo, J. C.; Soler, V.; Arzilli, F.; Brun, F.

    2016-12-01

    During the first week of the 2011 El Hierro submarine eruption, abundant light-coloured pumiceous, high-silica volcanic bombs coated in dark basanite were found floating on the sea. The composition of the light-coloured frothy material (`xeno-pumice') is akin to that of sedimentary rocks from the region, but the textures resemble felsic magmatic pumice, leaving their exact mode of formation unclear. To help decipher their origin, we investigated representative El Hierro xeno-pumice samples using X-ray computed microtomography for their internal vesicle shapes, volumes, and bulk porosity, as well as for the spatial arrangement and size distributions of vesicles in three dimensions (3D). We find a wide range of vesicle morphologies, which are especially variable around small fragments of rock contained in the xeno-pumice samples. Notably, these rock fragments are almost exclusively of sedimentary origin, and we therefore interpret them as relicts an the original sedimentary ocean crust protolith(s). The irregular vesiculation textures observed probably resulted from pulsatory release of volatiles from multiple sources during xeno-pumice formation, most likely by successive release of pore water and mineral water during incremental heating and decompression of the sedimentary protoliths.

  10. Dissolved gas geochemical signatures of the ground waters related to the 2011 El Hierro magmatic reactivation

    NASA Astrophysics Data System (ADS)

    Rodríguez, F.; Hernández, P. A.; Padrón, E.; Pérez, N. M.; Sumino, H.; Melián, G. V.; Padilla, G. D.; Barrancos, J.; Dionis, S.; Nolasco, D.; Calvo, D.; Hernández, I.; Peraza, M. D.

    2012-04-01

    El Hierro Island is the south westernmost and the youngest island of the Canary archipelago (<1.2 My). Since 16 July, an anomalous seismicity at El Hierro Island was recorded by IGN seismic network. After the occurrence of more than 10,000 seismic events, volcanic tremor was recorded since 05:15 on October 10, by all of the seismic stations on the island, with highest amplitudes recorded in the southernmost station. During the afternoon of 12 October a large light-green coloured area was observed in the sea to the south of La Restinga village (at the southernmost part of El Hierro island), suggesting the existence of a submarine eruption. Since October 12, frequent episodes of, turbulent gas emission and foaming, and the appearance of steamy lava fragments has been observed on the sea surface. Instituto Volcanologico de Canarias (INVOLCAN) started a hydrogeochemical program on August 2011 in order to evaluate the temporal evolution of dissolved gases on four different observation points (vertical and horizontal wells) of El Hierro. Three wells are located on the north of the island (where the seismic activity occurred at the beginning of the volcano-seismic unrest) and one horizontal well (gallery) in the south. At each observation point the concentration of dissolved helium, CO2, N2, O2 and Ar and the isotopic composition of He, C-CO2 and Ar have been measured three times per week. Significant increases on the dissolved gases content, mainly on CO2 and He/CO2 ratio, have been measured at all the observation points prior to the increasing of released seismic energy. Isotopic composition of dissolved helium, measured as 3He/4He ratio, showed an significant increase (from 1-3 RA up to 7.2 RA, being RA the isotopic 3He/4He ratio on air) at all the observation points 20 days before the occurrence of the submarine eruption and these relatively high 3He/4He values have been maintained along the volcanic unrest period. The isotopic composition of CO2 has showed also

  11. Diffuse degassing He/CO2 ratio before and during the 2011-12 El Hierro submarine eruption, Canary Islands

    NASA Astrophysics Data System (ADS)

    Padrón, Eleazar; Hernández, Pedro A.; Melián, Gladys V.; Barrancos, José; Padilla, Germán; Pérez, Nemesio M.; Dionis, Samara; Rodríguez, Fátima; Asensio-Ramos, María; Calvo, David

    2015-04-01

    El Hierro Island (278 km2) is the youngest and the SW-most of the Canary Islands. On July 16, 2011, a seismic-volcanic crisis started with the occurrence of more than 11,900 seismic events and significant deformation along the island, culminating with the eruption onset in October 12. Since at El Hierro Islands there are not any surface geothermal manifestation (fumaroles, etc), we have focused our studies on soil degassing surveys. Between July 2011 to March 2012, seventeen diffuse CO2 and He emissions soil gas surveys were undertaken at El Hierro volcanic system (600 observation sites) with the aim to investigate the relationship between their temporal variations and the volcanic activity (Padrón et al., 2013; Melián et al., 2014). Based on the diffuse He/CO2 emission ratio, a sharp increase before the eruption onset was observed, reaching the maximum value on September 26 (6.8×10-5), sixteen days before the occurrence of the eruption. This increase coincided with an increase in seismic energy release during the volcanic unrest and occurred together with an increase on the 3He/4He isotopic ratio in groundwaters from a well in El Hierro Island (Padrón et al., 2013; from 2-3 RA to 7.2 RA where RA = 3He/4He ratio in air), one month prior to the eruption onset. Early degassing of new gas-rich magma batch at depth could explain the observed increase on the He/CO2 ratio, causing a preferential partitioning of CO2 in the gas phase with respect to the He, due to the lower solubility of CO2 than that of He in basaltic magmas. During the eruptive period (October 2011-March 2012) the prevalence of a magmatic CO2-dominated component is evident, as indicated by the generally lower He/CO2 ratios and high 3He/4He values (Padrón et al., 2013). The onset of the submarine eruption might have produced a sudden release of volcanic gases, and consequently, a decrease in the volcanic gas pressure of the magma bodies moving beneath the island, reflected by a drastic decrease in

  12. Diffuse CO_{2} degassing monitoring of the oceanic active volcanic island of El Hierro, Canary Islands, Spain

    NASA Astrophysics Data System (ADS)

    Hernández, Pedro A.; Norrie, Janice; Withoos, Yannick; García-Merino, Marta; Melián, Gladys; Padrón, Eleazar; Barrancos, José; Padilla, Germán; Rodríguez, Fátima; Pérez, Nemesio M.

    2017-04-01

    Even during repose periods, volcanoes release large amounts of gases from both visible (fumaroles, solfataras, plumes) and non-visible emanations (diffuse degassing). In the last 20 years, there has been considerable interest in the study of diffuse degassing as a powerful tool in volcano monitoring programs, particularly in those volcanic areas where there are no visible volcanic-hydrothermal gas emissions. Historically, soil gas and diffuse degassing surveys in volcanic environments have focused mainly on CO2 because it is, after water vapor, the most abundant gas dissolved in magma. As CO2 travels upward by advective-diffusive transport mechanisms and manifests itself at the surface, changes in its flux pattern over time provide important information for monitoring volcanic and seismic activity. Since 1998, diffuse CO2 emission has been monitored at El Hierro Island, the smallest and south westernmost island of the Canarian archipelago with an area of 278 km2. As no visible emanations occur at the surface environment of El Hierro, diffuse degassing studies have become the most useful geochemical tool to monitor the volcanic activity in this volcanic island. The island experienced a volcano-seismic unrest that began in July 2011, characterized by the location of a large number of relatively small earthquakes (M<2.5) beneath El Hierro at depths between 8 and 15 km. On October 12, 2011, a submarine eruption was confirmed during the afternoon of October 12, 2011 by visual observations off the coast of El Hierro, about 2 km south of the small village of La Restinga in the southernmost part of the island. During the pre-eruptive and eruptive periods, the time series of the diffuse CO2 emission released by the whole island experienced two significant increases. The first started almost 2 weeks before the onset of the submarine eruption, reflecting a clear geochemical anomaly in CO2 emission, most likely due to increasing release of deep seated magmatic gases to the

  13. Seismic tomography model reveals mantle magma sources of recent volcanic activity at El Hierro Island (Canary Islands, Spain)

    NASA Astrophysics Data System (ADS)

    García-Yeguas, Araceli; Ibáñez, Jesús M.; Koulakov, Ivan; Jakovlev, Andrey; Romero-Ruiz, M. Carmen; Prudencio, Janire

    2014-12-01

    We present a 3-D model of P and S velocities beneath El Hierro Island, constructed using the traveltime data of more than 13 000 local earthquakes recorded by the Instituto Geográfico Nacional (IGN, Spain) in the period from 2011 July to 2012 September. The velocity models were performed using the LOTOS code for iterative passive source tomography. The results of inversion were thoroughly verified using different resolution and robustness tests. The results reveal that the majority of the onshore area of El Hierro is associated with a high-velocity anomaly observed down to 10-12-km depth. This anomaly is interpreted as the accumulation of solid igneous rocks erupted during the last 1 Myr and intrusive magmatic bodies. Below this high-velocity pattern, we observe a low-velocity anomaly, interpreted as a batch of magma coming from the mantle located beneath El Hierro. The boundary between the low- and high-velocity anomalies is marked by a prominent seismicity cluster, thought to represent anomalous stresses due to the interaction of the batch of magma with crust material. The areas of recent eruptions, Orchilla and La Restinga, are associated with low-velocity anomalies surrounding the main high-velocity block. These eruptions took place around the island where the crust is much weaker than the onshore area and where the melted material cannot penetrate. These results put constraints on the geological model that could explain the origin of the volcanism in oceanic islands, such as in the Canaries, which is not yet clearly understood.

  14. Cyclic thermal behavior associated to the degassing process at El Hierro submarine volcano, Canary Islands.

    NASA Astrophysics Data System (ADS)

    Fraile-Nuez, E.; Santana-Casiano, J. M.; González-Dávila, M.

    2016-12-01

    One year after the ceasing of magmatic activity in the shallow submarine volcano of the island of El Hierro, significant physical-chemical anomalies produced by the degassing process as: (i) thermal anomalies increase of +0.44 °C, (ii) pH decrease of -0.034 units, (iii) total dissolved inorganic carbon, CT increase by +43.5 µmol kg-1 and (iv) total alkalinity, AT by +12.81 µmol kg-1 were still present in the area. These evidences highlight the potential role of the shallow degassing processes as a natural ecosystem-scale experiments for the study of significant effects of global change stressors on marine environments. Additionally, thermal time series obtained from a temporal yo-yo CTD study, in isopycnal components, over one of the most active points of the submarine volcano have been analyzed in order to investigate the behavior of the system. Signal processing of the thermal time series highlights a strong cyclic temperature period of 125-150 min at 99.9% confidence, due to characteristic time-scales revealed in the periodogram. These long cycles might reflect dynamics occurring within the shallow magma supply system below the island of El Hierro.

  15. Time lag between deformation and seismicity along monogenetic volcanic unrest periods: The case of El Hierro Island (Canary Islands)

    NASA Astrophysics Data System (ADS)

    Lamolda, Héctor; Felpeto, Alicia; Bethencourt, Abelardo

    2017-07-01

    Between 2011 and 2014 there were at least seven episodes of magmatic intrusion in El Hierro Island, but only the first one led to a submarine eruption in 2011-2012. In order to study the relationship between GPS deformation and seismicity during these episodes, we compare the temporal evolution of the deformation with the cumulative seismic energy released. In some of the episodes both deformation and seismicity evolve in a very similar way, but in others a time lag appears between them, in which the deformation precedes the seismicity. Furthermore, a linear correlation between decimal logarithm of intruded magma volume and decimal logarithm of total seismic energy released along the different episodes has been observed. Therefore, if a future magmatic intrusion in El Hierro Island follows this behavior with a proper time lag, we could have an a priori estimate on the order of magnitude the seismic energy released would reach.

  16. On the detection of thermohygrometric differences of Juniperus turbinata habitat between north and south faces in the island of El Hierro (Canary Islands)

    NASA Astrophysics Data System (ADS)

    Salva-Catarineu, Montserrat; Salvador-Franch, Ferran; Lopez-Bustins, Joan A.; Padrón-Padrón, Pedro A.; Cortés-Lucas, Amparo

    2016-04-01

    The current extent of Juniperus turbinata in the island of El Hierro is very small due to heavy exploitation for centuries. The recovery of its natural habitat has such a high environmental and scenic interest since this is a protected species in Europe. The study of the environmental factors that help or limit its recovery is indispensable. Our research project (JUNITUR) studied the populations of juniper woodlands in El Hierro from different environments. These environments are mainly determined by their altitude and exposure to north-easterly trade winds. The main objective of this study was to compare the thermohygrometric conditions of three juniper woodlands: La Dehesa (north-west face at 528 m a.s.l.), El Julan (south face at 996 m a.s.l.) and Sabinosa (north face at 258 m a.s.l.). They are located at different altitude and orientation in El Hierro and present different recovery rates. We used air sensor data loggers fixed to tree branches for recording hourly temperature and humidity data in the three study areas. We analysed daily data of three annual cycles (from September 2012 to August 2015). Similar thermohygrometric annual cycles among the three study areas were observed. We detected the largest differences in winter temperature and summer humidity between the north (to windward) (Sabinosa and La Dehesa) and south (to leeward) (El Julan) faces of the island. The juniper woodland with a highest recovery rate (El Julan) showed the most extreme temperature conditions in both winter and summer seasons. The results of this project might contribute to the knowledge of the juniper bioclimatology in El Hierro, where there is the biggest population of Juniperus turbinata throughout the Canary Islands.

  17. Repeated magmatic intrusions at El Hierro Island following the 2011-2012 submarine eruption

    NASA Astrophysics Data System (ADS)

    Benito-Saz, Maria A.; Parks, Michelle M.; Sigmundsson, Freysteinn; Hooper, Andrew; García-Cañada, Laura

    2017-09-01

    After more than 200 years of quiescence, in July 2011 an intense seismic swarm was detected beneath the center of El Hierro Island (Canary Islands), culminating on 10 October 2011 in a submarine eruption, 2 km off the southern coast. Although the eruption officially ended on 5 March 2012, magmatic activity continued in the area. From June 2012 to March 2014, six earthquake swarms, indicative of magmatic intrusions, were detected underneath the island. We have studied these post-eruption intrusive events using GPS and InSAR techniques to characterize the ground surface deformation produced by each of these intrusions, and to determine the optimal source parameters (geometry, location, depth, volume change). Source inversions provide insight into the depth of the intrusions ( 11-16 km) and the volume change associated with each of them (between 0.02 and 0.13 km3). During this period, > 20 cm of uplift was detected in the central-western part of the island, corresponding to approximately 0.32-0.38 km3 of magma intruded beneath the volcano. We suggest that these intrusions result from deep magma migrating from the mantle, trapped at the mantle/lower crust discontinuity in the form of sill-like bodies. This study, using joint inversion of GPS and InSAR data in a post-eruption period, provides important insight into the characteristics of the magmatic plumbing system of El Hierro, an oceanic intraplate volcanic island.

  18. Eighteen years of geochemical monitoring at the oceanic active volcanic island of El Hierro (Canary Islands, Spain)

    NASA Astrophysics Data System (ADS)

    Asensio-Ramos, María; Alonso, Mar; Sharp, Emerson; Woods, Hannah; Barrancos, José; Pérez, Nemesio M.

    2016-04-01

    We report herein the latest results of a diffuse CO2 efflux survey at El Hierro volcanic system carried out during the summer period of 2015 to constrain the total CO2 output from the studied area a during post-eruptive period. El Hierro Island (278 km2) is the youngest and the SW-most of the Canary Islands. On July 16, 2011, a seismic-volcanic crisis started with the occurrence of more than 11,900 seismic events and significant deformation along the island. On October 10, 2011, the dominant character of seismicity changed dramatically from discrete earthquakes to continuous tremor, a clear indication that magma was rapidly approaching the surface immediately before the onset of the eruption, October 12. Eruption was declared over on 5 March, 2012. In order to monitor the volcanic activity of El Hierro Island, from 1998 to 2015 diffuse CO2 emission studies have been performed at El Hierro volcanic system in a yearly basis (˜600 observation sites) according to the accumulation chamber method. Spatial distribution maps were constructed following the sequential Gaussian simulation (sGs) procedure. To quantify the total CO2 emission from the studied area, 100 simulations for each survey have been performed. During the eruption period, soil CO2 efflux values range from non-detectable (˜0.5 g m-2 d-1) up to 457 g m-2 d-1, reaching in November 27, 2011, the maximum CO2 output estimated value of all time series, 2,398 t d-1, just before the episodes of maximum degassing observed as vigorous bubbling at the sea surface and an increment in the amplitude of the tremor signal. During the 2015 survey, soil CO2 efflux values ranged from non-detectable up to 41 g m-2 d-1. The spatial distribution of diffuse CO2 emission values seemed to be controlled by the main volcano structural features of the island. The total diffuse CO2 output released to atmosphere was estimated at 575 ± 24 t d-1, value slightly higher that the background CO2 emission estimated at 422 t d-1 (Melián et

  19. Origin of three-armed rifts in volcanic islands: the case of El Hierro (Canary Islands)

    NASA Astrophysics Data System (ADS)

    Galindo Jiménez, Inés; Becerril Carretero, Laura; Martí Molist, Joan; Gudmundsson, Agust

    2015-04-01

    Rifts zones in volcanic oceanic islands are common structures that have been explained through several theories/models. However, despite all these models it is as yet unclear whether it is the intense intrusive activity or the sector collapses that actually control the structural evolution and geometry of oceanic-island rift zones. Here we provide a new hypothesis to explain the origin and characteristics of the feeding system of oceanic-island rift zones based on the analysis of more than 1700 surface, subsurface (water galleries), and submarine structural data from El Hierro (Canary Islands). El Hierro's geological structure is primarily controlled by a three-armed rift-zone, the arms striking NE, WSW and S. Between the rift axes there are three valleys formed during huge landslides: El Golfo, El Julan, and Las Playas. Our results show: (1) a predominant NE-SW strike of structural elements, which coincides with the main regional trend of the Canary Archipelago as a whole; (2) a clear radial strike distribution of structural elements for the whole volcanic edifice (including submarine flanks) with respect to the centre of the island; (3) that the rift zones are mainly subaerial structures and do not propagate through the submarine edifice; (4) that it is only in the NE rift that structures have a general strike similar to that of the rift as a whole, and; (5) that in the W and S rifts there is not clear main direction, showing the structural elements in the W rift a fan distribution coinciding with the general radial pattern in the island as a whole. Based on these data, we suggest that the radial-striking structures reflect comparatively uniform stress fields that operated during the constructive episodes, mainly conditioned by the combination of overburden pressure, gravitational spreading, and magma-induced stresses. By contrast, in the shallower parts of the edifice, that is, the NE-SW, N-S and WNW-ESE-striking structures, reflect local stress fields related

  20. Lithospheric magma dynamics beneath the El Hierro Volcano, Canary Islands: insights from fluid inclusions

    NASA Astrophysics Data System (ADS)

    Oglialoro, E.; Frezzotti, M. L.; Ferrando, S.; Tiraboschi, C.; Principe, C.; Groppelli, G.; Villa, I. M.

    2017-10-01

    At active volcanoes, petrological studies have been proven to be a reliable approach in defining the depth conditions of magma transport and storage in both the mantle and the crust. Based on fluid inclusion and mineral geothermobarometry in mantle xenoliths, we propose a model for the magma plumbing system of the Island of El Hierro (Canary Islands). The peridotites studied here were entrained in a lava flow exposed in the El Yulan Valley. These lavas are part of the rift volcanism that occurred on El Hierro at approximately 40-30 ka. The peridotites are spinel lherzolites, harzburgites, and dunites which equilibrated in the shallow mantle at pressures between 1.5 and 2 GPa and at temperatures between 800 and 950 °C (low-temperature peridotites; LT), as well as at higher equilibration temperatures of 900 to 1100 °C (high-temperature peridotites; HT). Microthermometry and Raman analyses of fluid inclusions reveal trapping of two distinct fluid phases: early type I metasomatic CO2-N2 fluids ( X N2 = 0.01-0.18; fluid density (d) = 1.19 g/cm3), coexisting with silicate-carbonate melts in LT peridotites, and late type II pure CO2 fluids in both LT (d = 1.11-1.00 and 0.75-0.65 g/cm3) and HT ( d = 1.04-1.11 and 0.75-0.65 g/cm3) peridotites. While type I fluids represent metasomatic phases in the deep oceanic lithosphere (at depths of 60-65 km) before the onset of magmatic activity, type II CO2 fluids testify to two fluid trapping episodes during the ascent of xenoliths in their host mafic magmas. Identification of magma accumulation zones through interpretation of type II CO2 fluid inclusions and mineral geothermobarometry indicate the presence of a vertically stacked system of interconnected small magma reservoirs in the shallow lithospheric mantle between a depth of 22 and 36 km (or 0.67 to 1 GPa). This magma accumulation region fed a short-lived magma storage region located in the lower oceanic crust at a depth of 10-12 km (or 0.26-0.34 GPa). Following our model

  1. Significant discharge of CO2 from hydrothermalism associated with the submarine volcano of El Hierro Island

    NASA Astrophysics Data System (ADS)

    Santana-Casiano, J. M.; Fraile-Nuez, E.; González-Dávila, M.; Baker, E. T.; Resing, J. A.; Walker, S. L.

    2016-05-01

    The residual hydrothermalism associated with submarine volcanoes, following an eruption event, plays an important role in the supply of CO2 to the ocean. The emitted CO2 increases the acidity of seawater. The submarine volcano of El Hierro, in its degasification stage, provided an excellent opportunity to study the effect of volcanic CO2 on the seawater carbonate system, the global carbon flux, and local ocean acidification. A detailed survey of the volcanic edifice was carried out using seven CTD-pH-ORP tow-yo studies, localizing the redox and acidic changes, which were used to obtain surface maps of anomalies. In order to investigate the temporal variability of the system, two CTD-pH-ORP yo-yo studies were conducted that included discrete sampling for carbonate system parameters. Meridional tow-yos were used to calculate the amount of volcanic CO2 added to the water column for each surveyed section. The inputs of CO2 along multiple sections combined with measurements of oceanic currents produced an estimated volcanic CO2 flux = 6.0 105 ± 1.1 105 kg d-1 which is ~0.1% of global volcanic CO2 flux. Finally, the CO2 emitted by El Hierro increases the acidity above the volcano by ~20%.

  2. Significant discharge of CO2 from hydrothermalism associated with the submarine volcano of El Hierro Island.

    PubMed

    Santana-Casiano, J M; Fraile-Nuez, E; González-Dávila, M; Baker, E T; Resing, J A; Walker, S L

    2016-05-09

    The residual hydrothermalism associated with submarine volcanoes, following an eruption event, plays an important role in the supply of CO2 to the ocean. The emitted CO2 increases the acidity of seawater. The submarine volcano of El Hierro, in its degasification stage, provided an excellent opportunity to study the effect of volcanic CO2 on the seawater carbonate system, the global carbon flux, and local ocean acidification. A detailed survey of the volcanic edifice was carried out using seven CTD-pH-ORP tow-yo studies, localizing the redox and acidic changes, which were used to obtain surface maps of anomalies. In order to investigate the temporal variability of the system, two CTD-pH-ORP yo-yo studies were conducted that included discrete sampling for carbonate system parameters. Meridional tow-yos were used to calculate the amount of volcanic CO2 added to the water column for each surveyed section. The inputs of CO2 along multiple sections combined with measurements of oceanic currents produced an estimated volcanic CO2 flux = 6.0 10(5) ± 1.1 10(5 )kg d(-1) which is ~0.1% of global volcanic CO2 flux. Finally, the CO2 emitted by El Hierro increases the acidity above the volcano by ~20%.

  3. Significant discharge of CO2 from hydrothermalism associated with the submarine volcano of El Hierro Island

    PubMed Central

    Santana-Casiano, J. M.; Fraile-Nuez, E.; González-Dávila, M.; Baker, E. T.; Resing, J. A.; Walker, S. L.

    2016-01-01

    The residual hydrothermalism associated with submarine volcanoes, following an eruption event, plays an important role in the supply of CO2 to the ocean. The emitted CO2 increases the acidity of seawater. The submarine volcano of El Hierro, in its degasification stage, provided an excellent opportunity to study the effect of volcanic CO2 on the seawater carbonate system, the global carbon flux, and local ocean acidification. A detailed survey of the volcanic edifice was carried out using seven CTD-pH-ORP tow-yo studies, localizing the redox and acidic changes, which were used to obtain surface maps of anomalies. In order to investigate the temporal variability of the system, two CTD-pH-ORP yo-yo studies were conducted that included discrete sampling for carbonate system parameters. Meridional tow-yos were used to calculate the amount of volcanic CO2 added to the water column for each surveyed section. The inputs of CO2 along multiple sections combined with measurements of oceanic currents produced an estimated volcanic CO2 flux = 6.0 105 ± 1.1 105 kg d−1 which is ~0.1% of global volcanic CO2 flux. Finally, the CO2 emitted by El Hierro increases the acidity above the volcano by ~20%. PMID:27157062

  4. Palaeomagnetic constraints on the age of Lomo Negro volcanic eruption (El Hierro, Canary Islands)

    NASA Astrophysics Data System (ADS)

    Villasante-Marcos, Víctor; Pavón-Carrasco, Francisco Javier

    2014-12-01

    A palaeomagnetic study has been carried out in 29 cores drilled at six different sites from the volcanic products of Lomo Negro eruption (El Hierro, Canary Islands, Spain). Systematic thermal and alternating field demagnetization of the samples' natural remanent magnetization revealed a northward, stable palaeomagnetic direction similar in all the samples. Rock magnetic experiments indicate that this palaeomagnetic component is carried by a mixture of high-Ti and low-Ti titanomagnetite crystals typical of basaltic lithologies that have experienced a significant degree of oxyexsolution during subaerial cooling. The well constrained palaeomagnetic direction of Lomo Negro lavas was used to perform a palaeomagnetic dating of the volcanic event, using the SHA.DIF.14k global geomagnetic model restricted for the last 3000 yr. It can be unambiguously concluded that Lomo Negro eruption occurred well before the previously proposed date of 1793 AD, with three different age ranges being statistically possible during the last 3 ka: 115 BC-7 AD, 410-626 AD and 1499-1602 AD. The calibration of a previously published non-calibrated 14C dating suggests a XVI c. date for Lomo Negro eruption. This conclusion leaves open the possibility that the seismic crisis occurred at El Hierro in 1793 AD was related to an intrusive magmatic event that either did not reach the surface or either culminated in an unregistered submarine eruption similar to the one occurred in 2011-2012 at the southern off-shore ridge of the island.

  5. Precursory diffuse CO2 and H2S emission signatures of the 2011-2012 El Hierro submarine eruption, Canary Islands

    NASA Astrophysics Data System (ADS)

    Pérez, Nemesio M.; Padilla, Germán D.; Padrón, Eleazar; Hernández, Pedro A.; Melián, Gladys V.; Barrancos, José; Dionis, Samara; Nolasco, Dácil; Rodríguez, Fátima; Calvo, David; Hernández, Íñigo

    2012-08-01

    On October 12, 2011, a submarine eruption began 2 km off the coast of La Restinga, south of El Hierro Island. CO2 and H2S soil efflux were continuously measured during the period of volcanic unrest by using the accumulation chamber method at two different geochemical stations, HIE01 and HIE07. Recorded CO2 and H2S effluxes showed precursory signals that preceded the submarine eruption. Beginning in late August, the CO2 efflux time series started increasing at a relatively constant rate over one month, reaching a maximum of 19 gm-2d-1 one week before the onset of the submarine volcanic eruption. The H2S efflux time series at HIE07 showed a pulse in H2S emission just one day before the initiation of the submarine eruption, reaching peak values of 42 mg m-2 d-1, 10 times the average H2S efflux recorded during the observation period. Since CO2 and H2S effluxes are strongly influenced by external factors, we applied a multiple regression analysis to remove their contribution. A statistical analysis showed that the long-term trend of the filtered data is well correlated with the seismic energy. We find that these geochemical stations are important monitoring sites for evaluating the volcanic activity of El Hierro and that they demonstrate the potential of applying continuous monitoring of soil CO2 and H2S efflux to improve and optimize the detection of early warning signals of future volcanic unrest episodes at El Hierro. Continuous diffuse degassing studies would likely prove useful for monitoring other volcanoes during unrest episodes.

  6. Mode switching in volcanic seismicity: El Hierro 2011-2013

    NASA Astrophysics Data System (ADS)

    Roberts, Nick S.; Bell, Andrew F.; Main, Ian G.

    2016-05-01

    The Gutenberg-Richter b value is commonly used in volcanic eruption forecasting to infer material or mechanical properties from earthquake distributions. Such studies typically analyze discrete time windows or phases, but the choice of such windows is subjective and can introduce significant bias. Here we minimize this sample bias by iteratively sampling catalogs with randomly chosen windows and then stack the resulting probability density functions for the estimated b>˜ value to determine a net probability density function. We examine data from the El Hierro seismic catalog during a period of unrest in 2011-2013 and demonstrate clear multimodal behavior. Individual modes are relatively stable in time, but the most probable b>˜ value intermittently switches between modes, one of which is similar to that of tectonic seismicity. Multimodality is primarily associated with intermittent activation and cessation of activity in different parts of the volcanic system rather than with respect to any systematic inferred underlying process.

  7. Floating stones off El Hierro, Canary Islands: xenoliths of pre-island sedimentary origin in the early products of the October 2011 eruption

    NASA Astrophysics Data System (ADS)

    Troll, V. R.; Klügel, A.; Longpré, M.-A.; Burchardt, S.; Deegan, F. M.; Carracedo, J. C.; Wiesmaier, S.; Kueppers, U.; Dahren, B.; Blythe, L. S.; Hansteen, T. H.; Freda, C.; Budd, D. A.; Jolis, E. M.; Jonsson, E.; Meade, F. C.; Harris, C.; Berg, S. E.; Mancini, L.; Polacci, M.; Pedroza, K.

    2012-03-01

    A submarine eruption started off the south coast of El Hierro, Canary Islands, on 10 October 2011 and continues at the time of this writing (February 2012). In the first days of the event, peculiar eruption products were found floating on the sea surface, drifting for long distances from the eruption site. These specimens, which have in the meantime been termed "restingolites" (after the close-by village of La Restinga), appeared as black volcanic "bombs" that exhibit cores of white and porous pumice-like material. Since their brief appearance, the nature and origin of these "floating stones" has been vigorously debated among researchers, with important implications for the interpretation of the hazard potential of the ongoing eruption. The "restingolites" have been proposed to be either (i) juvenile high-silica magma (e.g. rhyolite), (ii) remelted magmatic material (trachyte), (iii) altered volcanic rock, or (iv) reheated hyaloclastites or zeolite from the submarine slopes of El Hierro. Here, we provide evidence that supports yet a different conclusion. We have analysed the textures and compositions of representative "restingolites" and compared the results to previous work on similar rocks found in the Canary Islands. Based on their high-silica content, the lack of igneous trace element signatures, the presence of remnant quartz crystals, jasper fragments and carbonate as well as wollastonite (derived from thermal overprint of carbonate) and their relatively high oxygen isotope values, we conclude that "restingolites" are in fact xenoliths from pre-island sedimentary layers that were picked up and heated by the ascending magma, causing them to partially melt and vesiculate. As they are closely resembling pumice in appearance, but are xenolithic in origin, we refer to these rocks as "xeno-pumice". The El Hierro xeno-pumices hence represent messengers from depth that help us to understand the interaction between ascending magma and crustal lithologies beneath the

  8. Magma displacements under insular volcanic fields, applications to eruption forecasting: El Hierro, Canary Islands, 2011-2013

    NASA Astrophysics Data System (ADS)

    García, A.; Fernández-Ros, A.; Berrocoso, M.; Marrero, J. M.; Prates, G.; De la Cruz-Reyna, S.; Ortiz, R.

    2014-04-01

    Significant deformations, followed by increased seismicity detected since 2011 July at El Hierro, Canary Islands, Spain, prompted the deployment of additional monitoring equipment. The climax of this unrest was a submarine eruption first detected on 2011 October 10, and located at about 2 km SW of La Restinga, southernmost village of El Hierro Island. The eruption ceased on 2012 March 5, after the volcanic tremor signals persistently weakened through 2012 February. However, the seismic activity did not end with the eruption, as several other seismic crises followed. The seismic episodes presented a characteristic pattern: over a few days the number and magnitude of seismic event increased persistently, culminating in seismic events severe enough to be felt all over the island. Those crises occurred in 2011 November, 2012 June and September, 2012 December to 2013 January and in 2013 March-April. In all cases the seismic unrest was preceded by significant deformations measured on the island's surface that continued during the whole episode. Analysis of the available GPS and seismic data suggests that several magma displacement processes occurred at depth from the beginning of the unrest. The first main magma movement or `injection' culminated with the 2011 October submarine eruption. A model combining the geometry of the magma injection process and the variations in seismic energy release has allowed successful forecasting of the new-vent opening.

  9. Observations of coupled seismicity and ground deformation at El Hierro Island (2011-2014)

    NASA Astrophysics Data System (ADS)

    Gonzalez, P. J.

    2015-12-01

    New insights into the magma storage and evolution at oceanic island volcanoes are now being achieved using remotely sensed space geodetic techniques, namely satellite radar interferometry. Differential radar interferometry is a technique tracking, at high spatial resolution, changes in the travel-time (distance) from the satellites to the ground surface, having wide applications in Earth sciences. Volcanic activity usually is accompanied by surface ground deformation. In many instances, modelling of surface deformation has the great advantage to estimate the magma volume change, a particularly interesting parameter prior to eruptions. Jointly interpreted with petrology, degassing and seismicity, it helps to understand the crustal magmatic systems as a whole. Current (and near-future) radar satellite missions will reduce the revisit time over global sub-aerial volcanoes to a sub-weekly basis, which will increase the potential for its operational use. Time series and filtering processing techniques of such streaming data would allow to track subsurface magma migration with high precision, and frequently update over vast areas (volcanic arcs, large caldera systems, etc.). As an example for the future potential monitoring scenario, we analyze multiple satellite radar data over El Hierro Island (Canary Islands, Spain) to measure and model surface ground deformation. El Hierro has been active for more than 3 years (2011 to 2014). Initial phases of the unrest culminated in a submarine eruption (late 2011 - early 2012). However, after the submarine eruption ended, its magmatic system still active and affected by pseudo-regular energetic seismic swarms, accompanied by surface deformation without resumed eruptions. Such example is a great opportunity to understand the crustal magmatic systems in low magma supply-rate oceanic island volcanoes. This new approach to measure surface deformation processes is yielding an ever richer level of information from volcanology to

  10. Multiparametric statistical investigation of seismicity occurred at El Hierro (Canary Islands) from 2011 to 2014

    NASA Astrophysics Data System (ADS)

    Telesca, Luciano; Lovallo, Michele; Lopez, Carmen; Marti Molist, Joan

    2016-03-01

    A detailed statistical investigation of the seismicity occurred at El Hierro volcano (Canary Islands) from 2011 to 2014 has been performed by analysing the time variation of four parameters: the Gutenberg-Richter b-value, the local coefficient of variation, the scaling exponent of the magnitude distribution and the main periodicity of the earthquake sequence calculated by using the Schuster's test. These four parameters are good descriptors of the time and magnitude distributions of the seismic sequence, and their variation indicate dynamical changes in the volcanic system. These variations can be attributed to the causes and types of seismicity, thus allowing to distinguish between different host-rock fracturing processes caused by intrusions of magma at different depths and overpressures. The statistical patterns observed among the studied unrest episodes and between them and the eruptive episode of 2011-2012 indicate that the response of the host rock to the deformation imposed by magma intrusion did not differ significantly from one episode to the other, thus suggesting that no significant local stress changes induced by magma intrusion occurred when comparing between all them. Therefore, despite the studied unrest episodes were caused by intrusions of magma at different depths and locations below El Hierro island, the mechanical response of the lithosphere was similar in all cases. This suggests that the reason why the first unrest culminated in an eruption while the other did not, may be related to the role of the regional/local tectonics acting at that moment, rather than to the forceful of magma intrusion.

  11. The submarine volcano eruption at the island of El Hierro: physical-chemical perturbation and biological response

    NASA Astrophysics Data System (ADS)

    Fraile-Nuez, E.; Santana-Casiano, J.; Gonzalez-Davila, M.

    2013-12-01

    On October 10 2011 an underwater eruption gave rise to a novel shallow submarine volcano south of the island of El Hierro, Canary Islands, Spain. During the eruption large quantities of mantle-derived gases, solutes and heat were released into the surrounding waters. In order to monitor the impact of the eruption on the marine ecosystem, periodic multidisciplinary cruises were carried out. Here, we present an initial report of the extreme physical-chemical perturbations caused by this event, comprising thermal changes, water acidification, deoxygenation and metal-enrichment, which resulted in significant alterations to the activity and composition of local plankton communities. Our findings highlight the potential role of this eruptive process as a natural ecosystem-scale experiment for the study of extreme effects of global change stressors on marine environments. (A) Natural color composite from the MEdium Resolution Imaging Spectrometer (MERIS) instrument aboard ENVISAT Satellite (European Space Agency), (November 9, 2011 at 14:45 UTC). Remote sensing data have been used to monitor the evolution of the volcanic emissions, playing a fundamental role during field cruises in guiding the Spanish government oceanographic vessel to the appropriate sampling areas. The inset map shows the position of Canary Islands west of Africa and the study area (solid white box). (B) Location of the stations carried out from November 2011 to February 2012 at El Hierro. Black lines denote transects A-B and C-D.

  12. Environmental monitoring of El Hierro Island submarine volcano, by combining low and high resolution satellite imagery

    NASA Astrophysics Data System (ADS)

    Eugenio, F.; Martin, J.; Marcello, J.; Fraile-Nuez, E.

    2014-06-01

    El Hierro Island, located at the Canary Islands Archipelago in the Atlantic coast of North Africa, has been rocked by thousands of tremors and earthquakes since July 2011. Finally, an underwater volcanic eruption started 300 m below sea level on October 10, 2011. Since then, regular multidisciplinary monitoring has been carried out in order to quantify the environmental impacts caused by the submarine eruption. Thanks to this natural tracer release, multisensorial satellite imagery obtained from MODIS and MERIS sensors have been processed to monitor the volcano activity and to provide information on the concentration of biological, chemical and physical marine parameters. Specifically, low resolution satellite estimations of optimal diffuse attenuation coefficient (Kd) and chlorophyll-a (Chl-a) concentration under these abnormal conditions have been assessed. These remote sensing data have played a fundamental role during field campaigns guiding the oceanographic vessel to the appropriate sampling areas. In addition, to analyze El Hierro submarine volcano area, WorldView-2 high resolution satellite spectral bands were atmospherically and deglinted processed prior to obtain a high-resolution optimal diffuse attenuation coefficient model. This novel algorithm was developed using a matchup data set with MERIS and MODIS data, in situ transmittances measurements and a seawater radiative transfer model. Multisensor and multitemporal imagery processed from satellite remote sensing sensors have demonstrated to be a powerful tool for monitoring the submarine volcanic activities, such as discolored seawater, floating material and volcanic plume, having shown the capabilities to improve the understanding of submarine volcanic processes.

  13. Short-term volcano-tectonic earthquake forecasts based on a moving mean recurrence time algorithm: the El Hierro seismo-volcanic crisis experience

    NASA Astrophysics Data System (ADS)

    García, Alicia; De la Cruz-Reyna, Servando; Marrero, José M.; Ortiz, Ramón

    2016-05-01

    Under certain conditions, volcano-tectonic (VT) earthquakes may pose significant hazards to people living in or near active volcanic regions, especially on volcanic islands; however, hazard arising from VT activity caused by localized volcanic sources is rarely addressed in the literature. The evolution of VT earthquakes resulting from a magmatic intrusion shows some orderly behaviour that may allow the occurrence and magnitude of major events to be forecast. Thus governmental decision makers can be supplied with warnings of the increased probability of larger-magnitude earthquakes on the short-term timescale. We present here a methodology for forecasting the occurrence of large-magnitude VT events during volcanic crises; it is based on a mean recurrence time (MRT) algorithm that translates the Gutenberg-Richter distribution parameter fluctuations into time windows of increased probability of a major VT earthquake. The MRT forecasting algorithm was developed after observing a repetitive pattern in the seismic swarm episodes occurring between July and November 2011 at El Hierro (Canary Islands). From then on, this methodology has been applied to the consecutive seismic crises registered at El Hierro, achieving a high success rate in the real-time forecasting, within 10-day time windows, of volcano-tectonic earthquakes.

  14. Seismic hydraulic fracture migration originated by successive deep magma pulses: The 2011-2013 seismic series associated to the volcanic activity of El Hierro Island

    NASA Astrophysics Data System (ADS)

    Díaz-Moreno, A.; Ibáñez, J. M.; De Angelis, S.; García-Yeguas, A.; Prudencio, J.; Morales, J.; Tuvè, T.; García, L.

    2015-11-01

    In this manuscript we present a new interpretation of the seismic series that accompanied eruptive activity off the coast of El Hierro, Canary Islands, during 2011-2013. We estimated temporal variations of the Gutenberg-Richter b value throughout the period of analysis, and performed high-precision relocations of the preeruptive and syneruptive seismicity using a realistic 3-D velocity model. Our results suggest that eruptive activity and the accompanying seismicity were caused by repeated injections of magma from the mantle into the lower crust. These magma pulses occurred within a small and well-defined volume resulting in the emplacement of fresh magma along the crust-mantle boundary underneath El Hierro. We analyzed the distribution of earthquake hypocenters in time and space in order to assess seismic diffusivity in the lower crust. Our results suggest that very high earthquake rates underneath El Hierro represent the response of a stable lower crust to stress perturbations with pulsatory character, linked to the injection of magma from the mantle. Magma input from depth caused large stress perturbations to propagate into the lower crust generating energetic seismic swarms. The absence of any preferential alignment in the spatial pattern of seismicity reinforces our hypothesis that stress perturbation and related seismicity, had diffusive character. We conclude that the temporal and spatial evolution of seismicity was neither tracking the path of magma migration nor it defines the boundaries of magma storage volumes such as a midcrustal sill. Our conceptual model considers pulsatory magma injection from the upper mantle and its propagation along the Moho. We suggest, within this framework, that the spatial and temporal distributions of earthquake hypocenters reflect hydraulic fracturing processes associated with stress propagation due to magma movement.

  15. Submarine seismic monitoring of El Hierro volcanic eruption with a 3C-geophone string: applying new acquisition and data processing techniques to volcano monitoring

    NASA Astrophysics Data System (ADS)

    Jurado, Maria Jose; Ripepe, Maurizio; Lopez, Carmen; Blanco, Maria Jose; Crespo, Jose

    2015-04-01

    A submarine volcanic eruption took place near the southernmost emerged land of the El Hierro Island (Canary Islands, Spain), from October 2011 to February 2012. The Instituto Geografico Nacional (IGN) seismic stations network evidenced seismic unrest since July 2011 and was a reference also to follow the evolution of the seismic activity associated with the volcanic eruption. Right after the eruption onset, in October 2011 a geophone string was deployed by the CSIC-IGN to monitor seismic activity. Monitoring with the seismic array continued till May 2012. The array was installed less than 2 km away from the new vol¬cano, next to La Restinga village shore in the harbor from 6 to 12m deep into the water. Our purpose was to record seismic activity related to the volcanic activity, continuously and with special interest on high frequency events. The seismic array was endowed with 8, high frequency, 3 component, 250 Hz, geophone cable string with a separation of 6 m between them. Each geophone consists on a 3-component module based on 3 orthogonal independent sensors that measures ground velocity. Some of the geophones were placed directly on the seabed, some were buried. Due to different factors, as the irregular characteristics of the seafloor. The data was recorded on the surface with a seismometer and stored on a laptop computer. We show how acoustic data collected underwater show a great correlation with the seismic data recorded on land. Finally we compare our data analysis results with the observed sea surface activity (ash and lava emission and degassing). This evidence is disclosing new and innovative tecniques on monitoring submarine volcanic activity. Reference Instituto Geográfico Nacional (IGN), "Serie El Hierro." Internet: http://www.ign.es/ign/resources /volcanologia/HIERRO.html [May, 17. 2013

  16. Spatial and temporal variations of diffuse CO2 degassing at El Hierro volcanic system: Relation to the 2011-2012 submarine eruption

    NASA Astrophysics Data System (ADS)

    Melián, Gladys; Hernández, Pedro A.; Padrón, Eleazar; Pérez, Nemesio M.; Barrancos, José; Padilla, Germán.; Dionis, Samara; Rodríguez, Fátima; Calvo, David; Nolasco, Dacil

    2014-09-01

    We report herein the results of extensive diffuse CO2 emission surveys performed on El Hierro Island in the period 1998-2012. More than 17,000 measurements of the diffuse CO2 efflux were carried out, most of them during the volcanic unrest period that started in July 2011. Two significant precursory signals based on geochemical and geodetical studies suggest that a magma intrusion processes might have started before 2011 in El Hierro Island. During the preeruptive and eruptive periods, the time series of the diffuse CO2 emission released by the whole island experienced two significant increases. The first started almost 2 weeks before the onset of the submarine eruption, reflecting a clear geochemical anomaly in CO2 emission, most likely due to increasing release of deep-seated magmatic gases to the surface. The second one, between 24 October and 27 November 2011, started before the most energetic seismic events of the volcanic-seismic unrest. The data presented here demonstrate that combined continuous monitoring studies and discrete surveys of diffuse CO2 emission provide important information to optimize the early warning system in volcano monitoring programs and to monitor the evolution of an ongoing volcanic eruption, even though it is a submarine eruption.

  17. Floating sandstones off El Hierro (Canary Islands, Spain): the peculiar case of the October 2011 eruption

    NASA Astrophysics Data System (ADS)

    Troll, V. R.; Klügel, A.; Longpré, M.-A.; Burchardt, S.; Deegan, F. M.; Carracedo, J. C.; Wiesmaier, S.; Kueppers, U.; Dahren, B.; Blythe, L. S.; Hansteen, T.; Freda, C.; Budd, D. A.; Jolis, E. M.; Jonsson, E.; Meade, F.; Berg, S.; Mancini, L.; Polacci, M.

    2011-12-01

    The eruption that started off the south coast of El Hierro, Canary Islands, in October 2011 has emitted intriguing eruption products found floating in the sea. These specimens appeared as floating volcanic "bombs" that have in the meantime been termed "restingolites" (after the close-by village of La Restinga) and exhibit cores of white and porous pumice-like material. Currently the nature and origin of these "floating stones" is vigorously debated among researchers, with important implications for the interpretation of the hazard potential of the ongoing eruption. The "restingolites" have been proposed to be either (i) juvenile high-silica magma (e.g. rhyolite), (ii) remelted magmatic material (trachyte), (iii) altered volcanic rock, or (iv) reheated hyaloclastites or zeolite from the submarine slopes of El Hierro. Here, we provide evidence that supports yet a different conclusion. We have collected and analysed the structure and composition of samples and compared the results to previous work on similar rocks found in the archipelago. Based on their high silica content, the lack of igneous trace element signatures, and the presence of remnant quartz crystals, jasper fragments and carbonate relicts, we conclude that "restingolites" are in fact xenoliths from pre-island sedimentary rocks that were picked up and heated by the ascending magma causing them to partially melt and vesiculate. They hence represent messengers from depth that help us to understand the interaction between ascending magma and crustal lithologies in the Canary Islands as well as in similar Atlantic islands that rest on sediment/covered ocean crust (e.g. Cape Verdes, Azores). The occurrence of these "restingolites" does therefore not indicate the presence of an explosive high-silica magma that is involved in the ongoing eruption.

  18. On the relation between crustal deformation and seismicity during the 2012-2014 magmatic intrusions in El Hierro island.

    NASA Astrophysics Data System (ADS)

    Domínguez Cerdeña, Itahiza; García-Cañada, Laura; Ángeles Benito Saz, María; Del Fresno, Carmen

    2017-04-01

    The last volcanic eruption in the Canary Islands took place in 2011 less than 2 km offshore El Hierro island, after 3 months of measuring surface deformation (up to 5 cm) and locating more than 10 000 earthquakes. In the two years following the end of the submarine eruption on 5 March 2012, six deep magmatic intrusions were recorded beneath the island. Despite the short time duration of these intrusions, these events have been more energetic that the 2011 pre-eruptive intrusive event but none of them ended in a new eruption. These post-eruptive reactivations are some of the few examples in the world of well monitored magmatic intrusions related with monogenetic volcanism. In order to understand these processes we have analyzed the geodetic and seismic data with different techniques. First, we did a joint hypocentral relocation of the six seismic swarms, including more than 6 300 events, to analyze the relative distribution of the earthquakes from different intrusions. The uncertainties of the earthquakes relocations was reduced to an average value of 300 m. New earthquakes' distribution shows the alignments of the different intrusions and a temporal migration of the events to larger depths. Moreover, we show the results of the ground deformation using GPS data from the network installed on the island (for each of the six intrusive events) and their inversion considering spherical models. In most of the intrusions the optimal source model was shallower and southern than the corresponding seismicity hypocenters. The intruded magma volume ranges from 0.02 to 0.13 km3. Finally, we also computed the b value from the Gutenberg Richter equation by means of a bootstrap method. The spatial and temporal evolution of the b value for the seismicity show a clear correlation with the temporal evolution of the crustal deformation. The six magma intrusions can be grouped, depending on their location, in three pairs each one associated with each of the three active rifts of El

  19. Magnetic imaging of the feeding system of oceanic volcanic islands: El Hierro (Canary Islands)

    NASA Astrophysics Data System (ADS)

    Blanco-Montenegro, Isabel; Nicolosi, Iacopo; Pignatelli, Alessandro; Chiappini, Massimo

    2008-04-01

    El Hierro is the youngest of the Canary Islands, a volcanic archipelago in the central Atlantic, near the African coast. The subaerial part of the island shows the characteristic shape of three convergent ridges that has been interpreted as a triple-arm rift system. At least four giant landslides formed wide, horseshoe embayments that separate these ridges. Recent studies based on high-resolution bathymetry, however, showed that the submarine rift structure is much more complex. We analysed an aeromagnetic anomaly data set acquired in 1993 by the Spanish National Geographic Institute in order to obtain a structural model of the island from a magnetic point of view. A digital elevation model of the volcanic edifice was divided into a mesh of prismatic cells, each of them with a top corresponding to the topographic height (or bathymetric depth in the marine area) and a bottom at a constant depth of 4000 m below sea level. A three-dimensional (3-D) inversion algorithm and forward modelling along representative profiles provided us with a magnetization distribution containing valuable information about the inner structure of the island. The magnetic model cast new light on the rift structure of El Hierro. In particular, high magnetization values have been mainly interpreted as intrusive complexes on which rift zones are rooted. Their location confirms the hypothesis of a complex rift structure in the marine area. The inverse magnetization that characterizes the NE submarine rift area implies that this part of the volcanic edifice formed during the Matuyama and, therefore, predates the NW submarine rift zone, which is normally magnetized. The N-S rift zone extending southwards from the island seems to be shifted to the west with respect to the bathymetric high in this area. This result suggests that the original rift zone was located in the area where the highest magnetizations presently occur so that the present morphology may reflect the westward collapse of the

  20. Fracture and damage localization in volcanic edifice rocks from El Hierro, Stromboli and Tenerife.

    PubMed

    Harnett, Claire E; Benson, Philip M; Rowley, Pete; Fazio, Marco

    2018-01-31

    We present elastic wave velocity and strength data from a suite of three volcanic rocks taken from the volcanic edifices of El Hierro and Tenerife (Canary Islands, Spain), and Stromboli (Aeolian Islands, Italy). These rocks span a range of porosity and are taken from volcanoes that suffer from edifice instability. We measure elastic wave velocities at known incident angles to the generated through-going fault as a function of imposed strain, and examine the effect of the damage zone on P-wave velocity. Such data are important as field measurements of elastic wave tomography are key tools for understanding volcanic regions, yet hidden fractures are likely to have a significant effect on elastic wave velocity. We then use elastic wave velocity evolution to calculate concomitant crack density evolution which ranges from 0 to 0.17: highest values were correlated to the damage zone in rocks with the highest initial porosity.

  1. Diffuse H_{2} emission: a useful geochemical tool to monitor the volcanic activity at El Hierro volcano system

    NASA Astrophysics Data System (ADS)

    Pérez, Nemesio M.; Melián, Gladys; González-Santana, Judit; Barrancos, José; Padilla, Germán; Rodríguez, Fátima; Padrón, Eleazar; Hernández, Pedro A.

    2016-04-01

    The occurrence of interfering processes affecting reactive gases as CO2 during its ascent from magmatic bodies or hydrothermal systems toward the surface environment hinders the interpretation of their enrichments in the soil atmosphere and fluxes for volcano monitoring purposes (Marini and Gambardella, 2005). These processes include gas scrubbing by ground-waters and interaction with rocks, decarbonatation processes, biogenic production, etc. Within the rest of the soil gases, particularly interest has been addressed to light and highly mobile gases. They offer important advantages for the detection of vertical permeability structures, because their interaction with the surrounding rocks or fluids during the ascent toward the surface is minimum. H2 is one of the most abundant trace species in volcano-hydrothermal systems and is a key participant in many redox reactions occurring in the hydrothermal reservoir gas (Giggenbach, 1987). Although H2 can be produced in soils by N2-fixing and fertilizing bacteria, soils are considered nowadays as sinks of molecular hydrogen (Smith-Downey et al., 2006). Because of its chemical and physical characteristics, H2 generated within the crust moves rapidly and escapes to the atmosphere. These characteristics make H2 one of the best geochemical indicators of magmatic and geothermal activity at depth. El Hierro is the youngest and the SW-most of the Canary Islands and the scenario of the last volcanic eruption of the archipelago, a submarine eruption that took place 2 km off the southern coast of the island from October 2011 to March 2012. Since at El Hierro Island there are not any surface geothermal manifestations (fumaroles, etc), we have focused our studies on soil degassing surveys. Here we show the results of soil H2 emission surveys that have been carried out regularly since mid-2012. Soil gas samples were collected in ˜600 sites selected based on their accessibility and geological criteria. Soil gases were sampled at ˜40

  2. The 2011 submarine volcanic eruption of El Hierro Island (Canary Islands, Spain)

    NASA Astrophysics Data System (ADS)

    López, C.; Blanco, M. J.

    2012-04-01

    On 10 October 2011 a submarine volcanic eruption began 2 km SW of La Restinga village in the South coast of El Hierro Island (Spain). It became the first submarine eruption reported in 500 years of historical record in the Canary Islands. The eruption took place after three months of intensive seismic activity and ground deformation. The first signal evidencing the eruption was a harmonic tremor signal, located somewhere in the South sector of El Hierro Island and registered in every seismic station on the island. On the following day, the tremoŕs amplitude increased up enough to be felt by the residents of La Restinga. The first visual evidence of the eruption was observed during the afternoon of 12 October, a large light-green coloured area on the sea surface, 2 km to the SW of La Restinga. Three days later, steaming lava fragments were observed floating on the sea, in the area where the vent was supposed to be located. These fragments had a bomb-like shape and their sizes ranged between 10 and 40 cm long. They were bicoloured, a black outer part with a basaltic composition, and a white inner part, highly vesiculated and rich in silica content (>60%). This type of fragments was only observed during the first days of the eruption. Within the next two months further emission episodes have been observed with turbulent water, foam rings and large bubbles on the sea surface. On the 27th of November new lava fragments were observed while floating and degassing on the sea surface. Most of them were "lava balloons" or hollow fragments of lavas, with sizes between 30 and 200 cm, and highly vesiculated outer crust of basaltic-basanitic and sideromelane composition. The emission of these products continues intermitently up to date (January 2012) During the eruption, the GPS monitoring network detected episodes of inflation-deflation and a maximum vertical deformation of 4 cm. The horizontal deformation, which had reached up to 5 cm before the eruption, remains stable. The

  3. Mantle to surface degassing of carbon- and sulphur-rich alkaline magma at El Hierro, Canary Islands

    NASA Astrophysics Data System (ADS)

    Longpré, Marc-Antoine; Stix, John; Klügel, Andreas; Shimizu, Nobumichi

    2017-02-01

    Basaltic volcanoes transfer volatiles from the mantle to the surface of the Earth. The quantification of deep volatile fluxes relies heavily on estimates of the volatile content of primitive magmas, the best archive of which is provided by melt inclusions. Available data from volcanoes producing mafic alkaline lavas in a range of tectonic settings suggest high volatile fluxes, but information remains sparse, particularly for intraplate ocean islands. Here we present measurements of volatile and trace element concentrations, as well as sulphur speciation, in olivine-hosted melt inclusions and matrix glasses from quenched basanite lava balloon samples from the 2011-2012 submarine eruption at El Hierro, Canary Islands. The results reveal remarkably high concentrations of dissolved volatiles and incompatible trace elements in this magma, with ∼80 ppm Nb and up to 3420 ppm CO2, 3.0 wt.% H2O and 5080 ppm S. Reconstructed primitive CO2 contents, considering CO2/Nb systematics and possible CO2 sequestration in shrinkage bubbles, reach weight percent levels, indicating that carbon is a major constituent of Canary Island magmas at depth and that exsolution of a CO2-rich fluid begins in the mantle at pressures in excess of 1 GPa. Correlations between sulphur concentration, sulphur speciation and water content suggest strong reduction of an initially oxidised mantle magma, likely controlled by coupled H2O and S degassing. This late-stage redox change may have triggered sulphide saturation, recorded by globular sulphide inclusions in clinopyroxene and ulvöspinel. The El Hierro basanite thus had a particularly high volatile-carrying capacity and released a minimum of 1.3-2.1 Tg CO2 and 1.8-2.9 Tg S to the environment, causing substantial stress on the local submarine ecosystem. These results highlight the important contribution of alkaline ocean island volcanoes, such as the Canary Islands, to volatile fluxes from the mantle.

  4. The submarine volcano eruption at the island of El Hierro: physical-chemical perturbation and biological response

    PubMed Central

    Fraile-Nuez, E.; González-Dávila, M.; Santana-Casiano, J. M.; Arístegui, J.; Alonso-González, I. J.; Hernández-León, S.; Blanco, M. J.; Rodríguez-Santana, A.; Hernández-Guerra, A.; Gelado-Caballero, M. D.; Eugenio, F.; Marcello, J.; de Armas, D.; Domínguez-Yanes, J. F.; Montero, M. F.; Laetsch, D. R.; Vélez-Belchí, P.; Ramos, A.; Ariza, A. V.; Comas-Rodríguez, I.; Benítez-Barrios, V. M.

    2012-01-01

    On October 10 2011 an underwater eruption gave rise to a novel shallow submarine volcano south of the island of El Hierro, Canary Islands, Spain. During the eruption large quantities of mantle-derived gases, solutes and heat were released into the surrounding waters. In order to monitor the impact of the eruption on the marine ecosystem, periodic multidisciplinary cruises were carried out. Here, we present an initial report of the extreme physical-chemical perturbations caused by this event, comprising thermal changes, water acidification, deoxygenation and metal-enrichment, which resulted in significant alterations to the activity and composition of local plankton communities. Our findings highlight the potential role of this eruptive process as a natural ecosystem-scale experiment for the study of extreme effects of global change stressors on marine environments. PMID:22768379

  5. Long-term volcanic hazard assessment on El Hierro (Canary Islands)

    NASA Astrophysics Data System (ADS)

    Becerril, L.; Bartolini, S.; Sobradelo, R.; Martí, J.; Morales, J. M.; Galindo, I.

    2014-07-01

    Long-term hazard assessment, one of the bastions of risk-mitigation programs, is required for land-use planning and for developing emergency plans. To ensure quality and representative results, long-term volcanic hazard assessment requires several sequential steps to be completed, which include the compilation of geological and volcanological information, the characterisation of past eruptions, spatial and temporal probabilistic studies, and the simulation of different eruptive scenarios. Despite being a densely populated active volcanic region that receives millions of visitors per year, no systematic hazard assessment has ever been conducted on the Canary Islands. In this paper we focus our attention on El Hierro, the youngest of the Canary Islands and the most recently affected by an eruption. We analyse the past eruptive activity to determine the spatial and temporal probability, and likely style of a future eruption on the island, i.e. the where, when and how. By studying the past eruptive behaviour of the island and assuming that future eruptive patterns will be similar, we aim to identify the most likely volcanic scenarios and corresponding hazards, which include lava flows, pyroclastic fallout and pyroclastic density currents (PDCs). Finally, we estimate their probability of occurrence. The end result, through the combination of the most probable scenarios (lava flows, pyroclastic density currents and ashfall), is the first qualitative integrated volcanic hazard map of the island.

  6. Modelling framework developed for managing and forecasting the El Hierro 2011-2014 unrest processes based on the analysis of the seismicity and deformation data rate.

    NASA Astrophysics Data System (ADS)

    Garcia, Alicia; Fernandez-Ros, Alberto; Berrocoso, Manuel; Marrero, Jose Manuel; Prates, Gonçalo; De la Cruz-Reyna, Servando; Ortiz, Ramon

    2014-05-01

    In July 2011 at El Hierro (Canary Islands, Spain), a volcanic unrest was detected, with significant deformations followed by increased seismicity. A submarine eruption started on 10 October 2011 and ceased on 5 March 2012, after the volcanic tremor signals persistently weakened through February 2012. However, the seismic activity did not end when the eruption, as several other seismic crises followed since. The seismic episodes presented a characteristic pattern: over a few days the number and magnitude of seismic event increased persistently, culminating in seismic events severe enough to be felt all over the island. In all cases the seismic activity was preceded by significant deformations measured on the island's surface that continued during the whole episode. Analysis of the available GNSS-GPS and seismic data suggests that several magma injection processes occurred at depth from the beginning of the unrest. A model combining the geometry of the magma injection process and the variations in seismic energy released has allowed successful forecasting of the new-vent opening. The model presented here places special emphasis on phenomena associated to moderate eruptions, as well as on volcano-tectonic earthquakes and landslides, which in some cases, as in El Hierro, may be more destructive than an eruption itself.

  7. The natural ocean acidification and fertilization event caused by the submarine eruption of El Hierro

    PubMed Central

    Santana-Casiano, J. M.; González-Dávila, M.; Fraile-Nuez, E.; de Armas, D.; González, A. G.; Domínguez-Yanes, J. F.; Escánez, J.

    2013-01-01

    The shallow submarine eruption which took place in October 10th 2011, 1.8 km south of the island of El Hierro (Canary Islands) allowed the study of the abrupt changes in the physical-chemical properties of seawater caused by volcanic discharges. In order to monitor the evolution of these changes, seven oceanographic surveys were carried out over six months (November 2011-April 2012) from the beginning of the eruptive stage to the post-eruptive phase. Here, we present dramatic changes in the water column chemistry including large decreases in pH, striking effects on the carbonate system, decreases in the oxygen concentrations and enrichment of Fe(II) and nutrients. Our findings highlight that the same volcano which was responsible for the creation of a highly corrosive environment, affecting marine biota, has also provided the nutrients required for the rapid recuperation of the marine ecosystem. PMID:23355953

  8. Emissions of Fe(II) and its kinetic of oxidation at Tagoro submarine volcano, El Hierro (Canary Islands)

    NASA Astrophysics Data System (ADS)

    González-Dávila, M.; Santana-González, C.; Santana-Casiano, J. M.

    2017-12-01

    The eruptive process that took place in October 2011 in the submarine volcano Tagoro off the Island of El Hierro (Canary Island) and the subsequent degasification stage, five months later, have increased the concentration of TdFe(II) (Total dissolved iron(II)) in the waters nearest to the volcanic edifice. In order to detect any variation in concentrations of TdFe(II) due to hydrothermal emissions, three cruises were carried out two years after the eruptive process in October 2013, March 2014, May 2015, March 2016 and November 2016. The results from these cruises confirmed important positive anomalies in TdFe(II), which coincided with negatives anomalies in pHF,is (pH in free scale, at in situ conditions) located in the proximity of the main cone. Maximum values in TdFe(II) both at the surface, associated to chlorophyll a maximum, and at the sea bottom, were also observed, showing the important influence of organic complexation and particle re-suspension processes. Temporal variability studies were carried out over periods ranging from hours to days in the stations located over the main and two secondary cones in the volcanic edifice with positive anomalies in TdFe(II) concentrations and negative anomalies in pHF,is values. Observations showed an important variability in both pHF,is and TdFe(II) concentrations, which indicated the volcanic area was affected by a degasification process that remained in the volcano after the eruptive phase had ceased. Fe(II) oxidation kinetic studies were also undertaken in order to analyze the effects of the seawater properties in the proximities of the volcano on the oxidation rate constants and t1/2 (half-life time) of ferrous iron. The increased TdFe(II) concentrations and the low associated pHF,is values acted as an important fertilization event in the seawater around the Tagoro volcano at the Island of El Hierro providing optimal conditions for the regeneration of the area.

  9. [In Process Citation].

    PubMed

    Wang, Bingsong; Li, Yijun; Wu, Xiaolu; Liu, Qingqing; Tang, Xue; Wang, Zuo

    2016-03-25

    Objetivos: oligoelementos como zinc (Zn), hierro (Fe) y cobre (Cu) tienen una influencia significativa en el mantenimiento de la función inmune y del metabolismo normales; modulan la función immune e influyen en la susceptibilidad del organismo ante infecciones. Pero la relación entre trazas de estos elementos y la bronconeumonía resultó incierta. Métodos: en este estudio fueron incluidos 28 niños con bronconeumonía y 46 niños sanos agrupados por edad. Se determinaron los niveles de Zn, Cu, Fe, calcio (Ca) y/o magnesio (Mg) en el suero de los niños con bronconeumonía y sin ella mediante espectrofotometría de absorción atómica. Resultados: los resultados muestran que varios niveles de microelementos como Zn, Ca, Mg y Fe en el grupo con bronconeumonía son menores que en el grupo control. En el grupo de niños con bronconeumonía el nivel de Ca en el suero está asociado positivamente con el zinc (Zn) (p < 0,05) y el hierro (Fe) (p < 0,05), mientras que hay una correlación positiva entre el cobre (Cu) y el calcio (Ca) (p < 0,05), magnesio (mg) (p < 0,05). Conclusión: el nivel de oligoelemento en el suero puede estar asociado con el riesgo de bronconeumonía entre los niños.

  10. Development and recent activity of the San Andrés landslide on El Hierro, Canary Islands, Spain

    NASA Astrophysics Data System (ADS)

    Klimeš, Jan; Yepes, Jorge; Becerril, Laura; Kusák, Michal; Galindo, Inés; Blahut, Jan

    2016-05-01

    Extremely voluminous landslides with a long run-out (also known as megalandslides) on oceanic volcanic islands are infrequent denudational processes on such islands. At the same time, they represent a major geological hazard that must be looked into to avoid negative consequences for the inhabitants of these islands. Their occurrence can be related to periods of intense seismo-volcanic activity, similar to that which occurred on El Hierro Island over 2011-2012. Landslides on volcanic islands are studied using onshore and offshore geological, geophysical and geomorphological records, considering their unique triggering conditions (e.g. lava intrusions, eruptive vents, magma chamber collapses). Previous work has pointed out similarities between specific cases of landslides on volcanic islands and deep-seated gravitational slope deformations (DSGSDs) which are typical in high mountain settings. Nevertheless, the methodological approaches and concepts used to investigate DSGSDs are not commonly applied on volcanic islands studies, even though their use may provide new information about the development stage, recent movements and future hazards. Therefore, this approach for studying the San Andrés landslide (SAL) on El Hierro (Canary Islands) has been developed applying a detailed morphological field mapping, an interpretation of digital elevation models, structural measurements, kinematic testing, and a precise movement monitoring system. The acquired information revealed a strong structural influence on the landslide morphology and the presence of sets of weakened planes acting as the sliding surfaces of the SAL or secondary landslides within its body. The presence of secondary landslides, deep erosive gullies, coastal cliffs and high on-shore relative relief also suggests a high susceptibility to future landslide movement. Direct monitoring on the landslide scarps and the slip plane, performed between February 2013 and July 2014, using an automated optical

  11. Processes of Compression-Expansion and Subsidence-Uplift detected by the Spatial Inclinometer (IESHI) in the El Hierro Island eruption (October, 2011)

    NASA Astrophysics Data System (ADS)

    Prates, G.; Berrocoso, M.; Fernández-Ros, A.; García, A.; Ortiz, R.

    2012-04-01

    El Hierro Island (Canary Islands, Spain) has undergone a submarine eruption a few kilometers to its southeast, detected October 10, on the rift alignment that cuts across the island. However, the seismicity level suddenly increased around July 17 and ground deformation was detected by the only continuously observed GNSS-GPS (Global Navigation Satellite Systems - Global Positioning System) benchmark FRON in the El Golfo area. Based on that information several other GNSS-GPS benchmarks were installed, some of which continuously observed as well. A normal vector analysis was applied to these collected data. The normal vector magnitude variation identified local extension-compression regimes, while the normal vector inclination showed the relative height variation between the three benchmarks that define the plan to which normal vector is analyzed. To accomplish this analysis the data was previously processed to achieve positioning solutions every 30 minutes using the Bernese GPS Software 5.0, further enhanced by a Discrete Kalman Filter, giving an overall millimeter level precision. These solutions were reached using the IGS (International GNSS Service) ultra-rapid orbits and the double-differenced ionosphere-free combination. With this strategy the positioning solutions were attained in near real-time. Later with the IGS rapid orbits the data was reprocessed to provide added confidence to the solutions. Two triangles were then considered, a smaller one located in the El Golfo area within the historically collapsed caldera, and a larger one defined by benchmarks placed in Valverde, El Golfo and La Restinga, the town closest to the eruption's location, covering almost the entire Island's surface above sea level. With these two triangles the pre-eruption and post-eruption deformation suffered by El Hierro's surface will be further analyzed.

  12. The 2011 El Hierro submarine eruption: estimation of erupted lava flow volume on the basis of helicopter thermal surveys

    NASA Astrophysics Data System (ADS)

    Hernández, P. A.; Calvari, S.; Calvo, D.; Marquez, A.; Padron, E.; Pérez, N.; Melian, G.; Padilla, G.; Barrancos, J.; Dionis, S.; Rodríguez, F.; Nolasco, D.; Hernández, I.

    2012-04-01

    El Hierro represents the summit of a volcanic shield elevating from the surrounding seafloor at depth of 4000 m to up to 1501 m above sea level. The island is believed to be near the present hotspot location in the Canaries with the oldest subaerial rocks dated at 1.12 Ma. The subaerial parts of the El Hierro rift zones (NE, NW and S Ridges) are characterized by tightly aligned dyke complexes with clusters of cinder cones as their surface expressions. Since 16 July, an anomalous seismicity at El Hierro Island was recorded by IGN seismic network. After the occurrence of more than 10,000 seismic events, volcanic tremor started at 05:15 on 10 October, followed on the afternoon of 12 October by a green discolouration of seawater, strong bubbling and degassing, and abundant bombs on a decimetre scale found floating on the ocean surface offshore, southwest of La Restinga village. The Canary Government raised the alert level from green to yellow on 10 October (3 colour basis: green, yellow, and red). Further episodes have occurred during November, December 2011 and January 2012, with turbulent water, foam rings, and volcanic material again reaching the sea surface. Colour of the discoloured area has changed frequently from light green to dark brown, depending on the eruptive activity. During the whole eruptive period, The Volcanological Institute of Canary Islands and the Helicopter Unit of the Spanish Civil Guard have carried out regularly thermal surveys with a hand held FLIR Thermal Camera P65. The images have been collected taking care of avoiding solar reflection (with cloudy weather) or at times of the day without direct sun light. Air temperature and humidity were measured with a handled thermo-hygrometer every time before the thermal image collection, and measurements were always performed at two fixed heights: 2000 and 1000 feet, and images were collected as perpendicular as possible to the surface. Together with thermal images, digital photos of the surface have

  13. Deployment of a seismic array for volcano monitoring during the ongoing submarine eruption at El Hierro, Canary Islands

    NASA Astrophysics Data System (ADS)

    Abella, R.; Almendros, J.; Carmona, E.; Martin, R.

    2012-04-01

    On 17 July 2011 there was an important increase of the seismic activity at El Hierro (Canary Islands, Spain). This increase was detected by the Volcano Monitoring Network (Spanish national seismic network) run by the Instituto Geográfico Nacional (IGN). As a consequence, the IGN immediately deployed a dense, complete monitoring network that included seismometers, GPS stations, geochemical equipment, magnetometers, and gravity meters. During the first three months of activity, the seismic network recorded over ten thousand volcano-tectonic earthquakes, with a maximum magnitude of 4.6. On 10 October 2011 an intense volcanic tremor started. It was a monochromatic signal, with variable amplitude and frequency content centered at about 1-2 Hz. The tremor onset was correlated with the initial stages of the submarine eruption that occurred from a vent located south of El Hierro island, near the village of La Restinga. At that point the IGN, in collaboration with the Instituto Andaluz de Geofísica, deployed a seismic array intended for volcanic tremor monitoring and analysis. The seismic array is located about 7 km NW of the submarine vent. It has a 12-channel, 24-bit data acquisition system sampling each channel at 100 sps. The array is composed by 1 three-component and 9 vertical-component seismometers, distributed in a flat area with an aperture of 360 m. The data provided by the seismic array are going to be processed using two different approaches: (1) near-real-time, to produce information that can be useful in the management of the volcanic crisis; and (2) detailed investigations, to study the volcanic tremor characteristics and relate them to the eruption dynamics. At this stage we are mostly dedicated to produce fast, near-real-time estimates. Preliminary results have been obtained using the maximum average cross-correlation method. They indicate that the tremor wavefronts are highly coherent among array stations and propagate across the seismic array with an

  14. Improvement forecasting of volcanic activity by applying a Kalman filter to the SSEM signal. The case of the El Hierro Island eruption (October 2011)

    NASA Astrophysics Data System (ADS)

    Garcia, A.; Berrocoso, M.; Marrero, J. M.; Ortiz, R.

    2012-04-01

    The FFM (Failure Forecast Method) is developed from the eruption of St. Helens, being repeatedly applied to forecast eruptions and recently to the prediction of seismic activity in active volcanic areas. The underwater eruption of El Hierro Island has been monitored from three months before starting (October 10, 2011). This allowed a large catalogue of seismic events (over 11000) and continuous recording seismic signals that cover the entire period. Since the beginning of the seismic-volcanic crisis (July 2011), the FFM was applied to the SSEM signal of seismic records. Mainly because El Hierro is a very small island, the SSEM has a high noise (traffic and oceanic noise). To improve the signal / noise ratio has been used a Kalman filter. The Kalman filter coefficients are adjusted using an inversion process based on forecasting errors occurred in the twenty days preceding. The application of this filter has been a significant improvement in the reliability of forecasts. The analysis of the results shows, before the start of the eruption, that 90% of the forecasts are obtained with errors less than 10 minutes with more than 24 hours in advance. It is noteworthy that the method predicts the events of greater magnitude and especially the beginning of each swarm of seismic events. At the time the eruption starts reducing the efficiency of the forecast 50% with a dispersion of more than one hour. This fact is probably due to decreased detectability by saturation of some of the seismic stations and decreased the average magnitude. However, the events of magnitude greater than 4 were predicted with an error less than 20 minutes.

  15. Monitoring El Hierro submarine volcanic eruption events with a submarine seismic array

    NASA Astrophysics Data System (ADS)

    Jurado, Maria Jose; Molino, Erik; Lopez, Carmen

    2013-04-01

    A submarine volcanic eruption took place near the southernmost emerged land of the El Hierro Island (Canary Islands, Spain), from October 2011 to February 2012. The Instituto Geografico Nacional (IGN) seismic stations network evidenced seismic unrest since July 2012 and was a reference also to follow the evolution of the seismic activity associated with the volcanic eruption. From the beginning of the eruption a geophone string was installed less than 2 km away from the new volcano, next to La Restinga village shore, to record seismic activity related to the volcanic activity, continuously and with special interest on high frequency events. The seismic array was endowed with 8, high frequency, 3 component, 250 Hz, geophone cable string with a separation of 6 m between them. The analysis of the dataset using spectral techniques allows the characterization of the different phases of the eruption and the study of its dynamics. The correlation of the data analysis results with the observed sea surface activity (ash and lava emission and degassing) and also with the seismic activity recorded by the IGN field seismic monitoring system, allows the identification of different stages suggesting the existence of different signal sources during the volcanic eruption and also the posteruptive record of the degassing activity. The study shows that the high frequency capability of the geophone array allow the study of important features that cannot be registered by the standard seismic stations. The accumulative spectral amplitude show features related to eruptive changes.

  16. Volcanic signatures in time gravity variations during the volcanic unrest on El Hierro (Canary Islands)

    NASA Astrophysics Data System (ADS)

    Sainz-Maza Aparicio, S.; Arnoso Sampedro, J.; Gonzalez Montesinos, F.; Martí Molist, J.

    2014-06-01

    Gravity changes occurring during the initial stage of the 2011-2012 El Hierro submarine eruption are interpreted in terms of the preeruptive signatures during the episode of unrest. Continuous gravity measurements were made at two sites on the island using the relative spring gravimeter LaCoste and Romberg gPhone-054. On 15 September 2011, an observed gravity decrease of 45 μGal, associated with the southward migration of seismic epicenters, is consistent with a lateral magma migration that occurred beneath the volcanic edifice, an apparently clear precursor of the eruption that took place 25 days later on 10 October 2011. High-frequency gravity signals also appeared on 6-11 October 2011, pointing to an occurring interaction between a magmatic intrusion and the ocean floor. These important gravity changes, with amplitudes varying from 10 to -90 μGal, during the first 3 days following the onset of the eruption are consistent with the northward migration of the eruptive focus along an active eruptive fissure. An apparent correlation of gravity variations with body tide vertical strain was also noted, which could indicate that concurrent tidal triggering occurred during the initial stage of the eruption.

  17. Searching for structural medium changes during the 2011 El Hierro (Spain) submarine eruption

    NASA Astrophysics Data System (ADS)

    Sánchez-Pastor, Pilar S.; Schimmel, Martin; López, Carmen

    2017-04-01

    Submarine volcanic eruptions are often difficult to study due to their restricted access that usually inhibits direct observations. That happened with the 2011 El Hierro eruption, which is the first eruption that has been tracked in real time in Canary Islands. For instance, despite the real-time tracking it was not possible to determine the exact end of the eruption. Besides, volcanic eruptions involve many dynamic (physical and chemical) processes, which cause structural changes in the surrounding medium that we expect to observe and monitor through passive seismic approaches. The purpose of this study is to detect and analyse these changes as well as to search for precursory signals to the eruption itself using ambient noise auto and cross-correlations. We employ different correlation strategies (classical and phase cross-correlation) and apply them to field data recorded by the IGN network during 2011 and 2012. The different preprocessing and processing steps are tested and compared to better understand the data, to find the robust signatures, and to define a routine work procedure. One of the problems we face is the presence of volcanic tremors, which cause a varying seismic response that we can not attribute to structural changes. So far, structural changes could not be detected unambiguously and we present our ongoing research in this field.

  18. Multi-event behavior of El Golfo landslide (El Hierro Island, Canary Archipelago)

    NASA Astrophysics Data System (ADS)

    León, Ricardo; Biain, Ander; Urgeles, Roger; Somoza, Luis; Ferrer, Mercedes; García-Crespo, Jesús; Francisco Mediato, José; Galindo, Inés; Yepes, Jorge; Gimenez-Moreno, Julia

    2017-04-01

    Based on the re-interpretation of a vast onshore-offshore data set, a new morpho-structural characterization of the El Golfo giant landslide in the island of El Hierro (Canary Archipelago, Spain) is presented. Offshore multibeam echosounder data, chirp sub-bottom profiles, multichannel seismic reflection data and onshore information from water wells and galleries have been analyzed to determine the nature of the event. The subaerial headscarp shows a non-continuous arcuate profile formed by two nested semi-circular amphitheaters that extend offshore along a smooth chute, suggesting the occurrence of at least two large retrogressive events. Channels/gullies and escarpments developed along the submarine sector of the scar also indicate smaller-scale events and predominance of sediment bypass. At the base of submerged island, two subunits within the related submarine mass transport deposit (MTD) are identified on multichannel seismic reflection profiles confirming the multi-event nature of the landslide. The MTD, identified as a debris avalanche, has a total estimated volume of 318 km3: 84 km3 and 234 km3, for the lower and upper subunits respectively. Data from wells and galleries show abrasion platforms with beach deposits at sea-level (0 masl) formed after the landslide scar and buried by the El Golfo post-collapse infill lavas, suggesting an age at least older than 23.5-82.5 ka for the landslide. This work has been supported by the projects IGCP-640 S4SLIDE, High resolution seabed mapping EASME/EMFF/2016/005 and CTM2010-09496-E. Keywords: Submarine landslides, volcanic islands, debris avalanche, Canary Islands

  19. Lack of impact of the El Hierro (Canary Islands) submarine volcanic eruption on the local phytoplankton community.

    PubMed

    Gómez-Letona, M; Arístegui, J; Ramos, A G; Montero, M F; Coca, J

    2018-03-16

    The eruption of a submarine volcano south of El Hierro Island (Canary Islands) in October 2011 led to major physical and chemical changes in the local environment. Large amounts of nutrients were found at specific depths in the water column above the volcano associated with suboxic layers resulting from the oxidation of reduced chemical species expelled during the eruptive phase. It has been suggested that the fertilization with these compounds enabled the rapid restoration of the ecosystem in the marine reserve south of the island once the volcanic activity ceased, although no biological evidence for this has been provided yet. To test the biological fertilization hypothesis on the pelagic ecosystem, we studied the evolution and variability in chlorophyll a, from in situ and remote sensing data, combined with information on phytoplankton and bacterial community structure during and after the eruptive episode. Remote sensing and in situ data revealed that no phytoplankton bloom took place neither during nor after the eruptive episode. We hypothesize that the fertilization by the volcano did not have an effect in the phytoplankton community due to the strong dilution of macro- and micronutrients caused by the efficient renewal of ambient waters in the zone.

  20. The Submarine Volcano Eruption off El Hierro Island: Effects on the Scattering Migrant Biota and the Evolution of the Pelagic Communities

    PubMed Central

    Ariza, Alejandro; Kaartvedt, Stein; Røstad, Anders; Garijo, Juan Carlos; Arístegui, Javier; Fraile-Nuez, Eugenio; Hernández-León, Santiago

    2014-01-01

    The submarine volcano eruption off El Hierro Island (Canary Islands) on 10 October 2011 promoted dramatic perturbation of the water column leading to changes in the distribution of pelagic fauna. To study the response of the scattering biota, we combined acoustic data with hydrographic profiles and concurrent sea surface turbidity indexes from satellite imagery. We also monitored changes in the plankton and nekton communities through the eruptive and post-eruptive phases. Decrease of oxygen, acidification, rising temperature and deposition of chemicals in shallow waters resulted in a reduction of epipelagic stocks and a disruption of diel vertical migration (nocturnal ascent) of mesopelagic organisms. Furthermore, decreased light levels at depth caused by extinction in the volcanic plume resulted in a significant shallowing of the deep acoustic scattering layer. Once the eruption ceased, the distribution and abundances of the pelagic biota returned to baseline levels. There was no evidence of a volcano-induced bloom in the plankton community. PMID:25047077

  1. The submarine volcano eruption off El Hierro Island: effects on the scattering migrant biota and the evolution of the pelagic communities.

    PubMed

    Ariza, Alejandro; Kaartvedt, Stein; Røstad, Anders; Garijo, Juan Carlos; Arístegui, Javier; Fraile-Nuez, Eugenio; Hernández-León, Santiago

    2014-01-01

    The submarine volcano eruption off El Hierro Island (Canary Islands) on 10 October 2011 promoted dramatic perturbation of the water column leading to changes in the distribution of pelagic fauna. To study the response of the scattering biota, we combined acoustic data with hydrographic profiles and concurrent sea surface turbidity indexes from satellite imagery. We also monitored changes in the plankton and nekton communities through the eruptive and post-eruptive phases. Decrease of oxygen, acidification, rising temperature and deposition of chemicals in shallow waters resulted in a reduction of epipelagic stocks and a disruption of diel vertical migration (nocturnal ascent) of mesopelagic organisms. Furthermore, decreased light levels at depth caused by extinction in the volcanic plume resulted in a significant shallowing of the deep acoustic scattering layer. Once the eruption ceased, the distribution and abundances of the pelagic biota returned to baseline levels. There was no evidence of a volcano-induced bloom in the plankton community.

  2. Petrological and geochemical Highlights in the floating fragments of the October 2011 submarine eruption offshore El Hierro (Canary Islands): Relevance of submarine hydrothermal processes

    NASA Astrophysics Data System (ADS)

    Rodriguez-Losada, Jose A.; Eff-Darwich, Antonio; Hernandez, Luis E.; Viñas, Ronaldo; Pérez, Nemesio; Hernandez, Pedro; Melián, Gladys; Martinez-Frías, Jesús; Romero-Ruiz, M. Carmen; Coello-Bravo, Juan Jesús

    2015-02-01

    This paper describes the main physical, petrological and geochemical features of the floating fragments that were emitted in the initial stages of the 2011-2012 submarine eruption off the coast of the Canarian island of El Hierro, located 380 km from the Northwest African Coast. It attempts to assess the potential of radiometric analyses to discern the intriguing origin of the floating fragments and the differences between their constituent parts. In this regard, the material that conforms the core of the fragments contains the largest concentration of uranium (U) ever found in volcanic rocks of the Canary Islands. This enrichment in U is not found in the content of thorium (Th), hence the floating fragments have an unusual U/Th ratio, namely equal to or larger than 3. Although the origin of this material is under discussion, it is proposed that the enrichment in U is the result of hydrothermal processes.

  3. Different deformation patterns using GPS in the volcanic process of El Hierro (Canary Island) 2011-2013

    NASA Astrophysics Data System (ADS)

    García-Cañada, Laura; José García-Arias, María; Pereda de Pablo, Jorge; Lamolda, Héctor; López, Carmen

    2014-05-01

    Ground deformation is one of the most important parameter in volcano monitoring. The detected deformations in volcanic areas can be precursors of a volcanic activity and contribute with useful information to study the evolution of an unrest, eruption or any volcanic process. GPS is the most common technique used to measure volcano deformations. It can be used to detect slow displacement rates or much larger and faster deformations associated with any volcanic process. In volcanoes the deformation is expected to be a mixed of nature; during periods of quiescence it will be slow or not present, while increased activity slow displacement rates can be detected or much larger and faster deformations can be measure due to magma intrusion, for example in the hours to days prior a eruption beginning. In response to the anomalous seismicity detected at El Hierro in July 2011, the Instituto Geográfico Nacional (IGN) improved its volcano monitoring network in the island with continuous GPS that had been used to measure the ground deformation associated with the precursory unrest since summer 2011, submarine eruption (October 2011-March 2012) and the following unrest periods (2012-2013). The continuous GPS time series, together with other techniques, had been used to evaluate the activity and to detect changes in the process. We investigate changes in the direction and module of the deformation obtained by GPS and they show different patterns in every unrest period, very close to the seismicity locations and migrations.

  4. [Nutrition and child development I; nutritional status of school children in a peripheral district of Madrid (Rev Clin Esp 1944; XII:87-94)].

    PubMed

    Grande Covián, F; Rof Carballo, J; Jiménez García, F; Morata Cernuda, A

    2014-09-01

    El estudio clínico del estado nutritivo de un grupo de niños en edad escolar, habitantes de un suburbio madrileño revela la existencia, relativamente rara, de signos carenciales específicos, que contrasta vivamente con el considerable retraso que se observa en su desarrollo somático. Los hechos parecen demostrar que el problema nutritivo de estos niños es sobre todo un problema cuantitativo. El retraso de la evolución está en relación con la insuficiencia global de la dieta y con el déficit de calcio que es probablemente el elemento individual con mayor grado de carencia en las dietas. La anemia que presenta el 98% de los niños no parece deberse únicamente a una deficiencia de hierro porque la dieta parece tener una cantidad adecuada; probablemente esté más en relación con el exiguo contenido de proteínas animales de la ración.

  5. [Lung transplantation in cystic fibrosis. The results of the Clínica Puerta de Hierro (Madrid) and the Hospital La Fe (Valencia)].

    PubMed

    Lázaro-Carrasco, M T; Morales, P; Ferreiro, M J; Borro, J M; Varela, A; Vicente, R; Ramos, F; Estada, J A

    1999-05-01

    Retrospective analysis of cystic fibrosis patients who underwent pulmonary transplantation at Clínica Puerta de Hierro, Madrid, and at Hospital La Fe, Valencia. Since the beginning of the programme and until March 1998, a total of 63 patients with cystic fibrosis were studied. Among transplanted patients, 18 were males and 16 females, with a mean age of 18.9 years. All patients underwent sequential bilateral pulmonary transplantation. After transplantation, the most common complication was bacterial pneumonia which affected all patients. Six patients had dehiscence or stenosis of the bronchial suture. Other specific complications of this condition by frequency were intestinal obstruction and diabetes mellitus. Six patients developed obliterans bronchiolitis and one of them underwent a repeat transplantation. Three out of the 34 patients died, and the likelihood of survival after one and three years was 94%. Respiratory function tests and PaO2 peaked at sixth post-transplantation month. Pulmonary transplantation is a therapeutic option to be considered for the patient with cystic fibrosis and severe involvement of his/her pulmonary disease.

  6. Focal mechanism of the seismic series prior to the 2011 El Hierro eruption

    NASA Astrophysics Data System (ADS)

    del Fresno, C.; Buforn, E.; Cesca, S.; Domínguez Cerdeña, I.

    2015-12-01

    The onset of the submarine eruption of El Hierro (10-Oct-2011) was preceded by three months of low-magnitude seismicity (Mw<4.0) characterized by a well documented hypocenter migration from the center to the south of the island. Seismic sources of this series have been studied in order to understand the physical process of magma migration. Different methodologies were used to obtain focal mechanisms of largest shocks. Firstly, we have estimated the joint fault plane solutions for 727 shocks using first motion P polarities to infer the stress pattern of the sequence and to determine the time evolution of principle axes orientation. Results show almost vertical T-axes during the first two months of the series and horizontal P-axes on N-S direction coinciding with the migration. Secondly, a point source MT inversion was performed with data of the largest 21 earthquakes of the series (M>3.5). Amplitude spectra was fitted at local distances (<20km). Reliability and stability of the results were evaluated with synthetic data. Results show a change in the focal mechanism pattern within the first days of October, varying from complex sources of higher non-double-couple components before that date to a simpler strike-slip mechanism with horizontal tension axes on E-W direction the week prior to the eruption onset. A detailed study was carried out for the 8 October 2011 earthquake (Mw=4.0). Focal mechanism was retrieved using a MT inversion at regional and local distances. Results indicate an important component of strike-slip fault and null isotropic component. The stress pattern obtained corresponds to horizontal compression in a NNW-SSE direction, parallel to the southern ridge of the island, and a quasi-horizontal extension in an EW direction. Finally, a simple source time function of 0.3s has been estimated for this shock using the Empirical Green function methodology.

  7. Fast-Turnoff Transient Electro-Magnetic (TEM) geophysical survey in the Peña de Hierro ("Berg of Iron") field area of the Mars Analog Research and Technology Experiment (MARTE)

    NASA Astrophysics Data System (ADS)

    Jernsletten, J. A.

    2004-12-01

    This report describes the outcome of a Fast-Turnoff Transient Electro-Magnetic (TEM) geophysical survey carried out in the Peña de Hierro ("Berg of Iron") field area of the Mars Analog Research and Technology Experiment (MARTE), during May and June of 2003. The MARTE Peña de Hierro field area is located between the towns of Rio Tinto and Nerva in the Andalucia region of Spain. It is about one hour drive West of the city of Sevilla, and also about one hour drive North of Huelva. The high concentration of dissolved iron (and smaller amounts of other metals) in the very acidic water in the Rio Tinto area gives the water its characteristic wine red color, and also means that the water is highly conductive, and such an acidic and conductive fluid is highly suited for exploration by electromagnetic methods. This naturally acidic environment is maintained by bacteria in the groundwater and it is these bacteria that are the main focus of the MARTE project overall, and of this supporting geophysical work. It is the goal of this study to be able to map the subsurface extent of the high conductivity (low resistivity) levels, and thus by proxy the subsurface extent of the acidic groundwater and the bacteria populations. In so doing, the viability of using electromagnetic methods for mapping these subsurface metal-rich water bodies is also examined and demonstrated, and the geophysical data will serve to support drilling efforts. The purpose of this field survey was an initial effort to map certain conductive features in the field area, in support of the drilling operations that are central to the MARTE project. These conductive features include the primary target of exploration for MARTE, the very conductive acidic groundwater in the area (which is extremely rich in metals). Other conductive features include the pyretic ore bodies in the area, as well as extensive mine tailings piles.

  8. Applying Fractal Dimensions and Energy-Budget Analysis to Characterize Fracturing Processes During Magma Migration and Eruption: 2011-2012 El Hierro (Canary Islands) Submarine Eruption

    NASA Astrophysics Data System (ADS)

    López, Carmen; Martí, Joan; Abella, Rafael; Tarraga, Marta

    2014-07-01

    The impossibility of observing magma migration inside the crust obliges us to rely on geophysical data and mathematical modelling to interpret precursors and to forecast volcanic eruptions. Of the geophysical signals that may be recorded before and during an eruption, deformation and seismicity are two of the most relevant as they are directly related to its dynamic. The final phase of the unrest episode that preceded the 2011-2012 eruption on El Hierro (Canary Islands) was characterized by local and accelerated deformation and seismic energy release indicating an increasing fracturing and a migration of the magma. Application of time varying fractal analysis to the seismic data and the characterization of the seismicity pattern and the strain and the stress rates allow us to identify different stages in the source mechanism and to infer the geometry of the path used by the magma and associated fluids to reach the Earth's surface. The results obtained illustrate the relevance of such studies to understanding volcanic unrest and the causes that govern the initiation of volcanic eruptions.

  9. A new Volcanic managEment Risk Database desIgn (VERDI): Application to El Hierro Island (Canary Islands)

    NASA Astrophysics Data System (ADS)

    Bartolini, S.; Becerril, L.; Martí, J.

    2014-11-01

    One of the most important issues in modern volcanology is the assessment of volcanic risk, which will depend - among other factors - on both the quantity and quality of the available data and an optimum storage mechanism. This will require the design of purpose-built databases that take into account data format and availability and afford easy data storage and sharing, and will provide for a more complete risk assessment that combines different analyses but avoids any duplication of information. Data contained in any such database should facilitate spatial and temporal analysis that will (1) produce probabilistic hazard models for future vent opening, (2) simulate volcanic hazards and (3) assess their socio-economic impact. We describe the design of a new spatial database structure, VERDI (Volcanic managEment Risk Database desIgn), which allows different types of data, including geological, volcanological, meteorological, monitoring and socio-economic information, to be manipulated, organized and managed. The root of the question is to ensure that VERDI will serve as a tool for connecting different kinds of data sources, GIS platforms and modeling applications. We present an overview of the database design, its components and the attributes that play an important role in the database model. The potential of the VERDI structure and the possibilities it offers in regard to data organization are here shown through its application on El Hierro (Canary Islands). The VERDI database will provide scientists and decision makers with a useful tool that will assist to conduct volcanic risk assessment and management.

  10. Evolution of submarine eruptive activity during the 2011-2012 El Hierro event as documented by hydroacoustic images and remotely operated vehicle observations

    NASA Astrophysics Data System (ADS)

    Somoza, L.; González, F. J.; Barker, S. J.; Madureira, P.; Medialdea, T.; de Ignacio, C.; Lourenço, N.; León, R.; Vázquez, J. T.; Palomino, D.

    2017-08-01

    Submarine volcanic eruptions are frequent and important events, yet they are rarely observed. Here we relate bathymetric and hydroacoustic images from the 2011 to 2012 El Hierro eruption with surface observations and deposits imaged and sampled by ROV. As a result of the shallow submarine eruption, a new volcano named Tagoro grew from 375 to 89 m depth. The eruption consisted of two main phases of edifice construction intercalated with collapse events. Hydroacoustic images show that the eruptions ranged from explosive to effusive with variable plume types and resulting deposits, even over short time intervals. At the base of the edifice, ROV observations show large accumulations of lava balloons changing in size and type downslope, coinciding with the area where floating lava balloon fallout was observed. Peaks in eruption intensity during explosive phases generated vigorous bubbling at the surface, extensive ash, vesicular lapilli and formed high-density currents, which together with periods of edifice gravitational collapse, produced extensive deep volcaniclastic aprons. Secondary cones developed in the last stages and show evidence for effusive activity with lava ponds and lava flows that cover deposits of stacked lava balloons. Chaotic masses of heterometric boulders around the summit of the principal cone are related to progressive sealing of the vent with decreasing or variable magma supply. Hornitos represent the final eruptive activity with hydrothermal alteration and bacterial mats at the summit. Our study documents the distinct evolution of a submarine volcano and highlights the range of deposit types that may form and be rapidly destroyed in such eruptions.Plain Language SummaryToday and through most of geological history, the greatest number and volume of volcanic eruptions on Earth have occurred underwater. However, in comparison to subaerial eruption, little is known about submarine eruptive processes as</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/FR-2011-02-08/pdf/2011-2746.pdf','FEDREG'); return false;" href="https://www.gpo.gov/fdsys/pkg/FR-2011-02-08/pdf/2011-2746.pdf"><span>76 FR 6843 - Additional Designations, Foreign Narcotics Kingpin Designation Act</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collection.action?collectionCode=FR">Federal Register 2010, 2011, 2012, 2013, 2014</a></p> <p></p> <p>2011-02-08</p> <p>..., Jaslico, Mexico; Vereda Del Canario 1, Guadalajara, Jalisco, Mexico; Puerto de <span class="hlt">Hierro</span>, Zapopan, Jalisco..., Jalisco, Mexico; Puerto de <span class="hlt">Hierro</span>, Zapopan, Jalisco, Mexico; Mexico City, Distrito Federal, Mexico.... RODRIGUEZ OLIVERA, Daniel (a.k.a. RODRIGUEZ MORFIN, Daniel), Puerto de <span class="hlt">Hierro</span>, Zapopan, Jalisco, Mexico...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017EGUGA..19.6282D','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017EGUGA..19.6282D"><span>Improvements on the seismic catalog previous to the 2011 El <span class="hlt">Hierro</span> eruption.</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Domínguez Cerdeña, Itahiza; del Fresno, Carmen</p> <p>2017-04-01</p> <p>Precursors from the submarine eruption of El <span class="hlt">Hierro</span> (Canary Islands) in 2011 included 10,000 low magnitude earthquakes and 5 cm crustal deformation within 81 days previous to the eruption onset on the 10th October. Seismicity revealed a 20 km horizontal migration from the North to the South of the island and depths ranging from 10 and 17 km with deeper events occurring further South. The earthquakes of the seismic catalog were manually picked by the IGN almost in real time, but there has not been a subsequent revision to check for new non located events jet and the completeness magnitude for the seismic catalog have strong changes during the entire swarm due to the variable number of events per day. In this work we used different techniques to improve the quality of the seismic catalog. First we applied different automatic algorithms to detect new events including the LTA-STA method. Then, we performed a semiautomatic system to correlate the new P and S detections with known phases from the original catalog. The new detected earthquakes were also located using Hypoellipse algorithm. The resulting new catalog included 15,000 new events mainly concentrated in the last weeks of the swarm and we assure a completeness magnitude of 1.2 during the whole series. As the seismicity from the original catalog was already relocated using hypoDD algorithm, we improved the location of the new events using a master-cluster relocation. This method consists in relocating earthquakes towards a cluster of well located events instead of a single event as the master-event method. In our case this cluster correspond to the relocated earthquakes from the original catalog. Finally, we obtained a new equation for the local magnitude estimation which allow us to include corrections for each seismic station in order to avoid local effects. The resulting magnitude catalog has a better fit with the moment magnitude catalog obtained for the strong earthquakes of this series in previous studies</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24161241','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24161241"><span>On the biology of Spiruroidea parasites of murine rodents on El <span class="hlt">Hierro</span> (Canary Islands, Spain) with molecular characterization of Streptopharagus greenbergi Wertheim, 1993.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Montoliu, Isabel; Sánchez, Santiago; Villa, Mercedes; Abreu-Acosta, Néstor; Martín-Alonso, Aarón; Fernández-Álvarez, Ángela; Foronda, Pilar</p> <p>2013-09-01</p> <p>This paper reports the role of darkling beetles Pimelia laevigata costipennis and Hegeter amaroides (Tenebrionidae) as intermediate hosts of spiruroid nematodes parasites of the black rat and house mouse of El <span class="hlt">Hierro</span> (Canary Islands). Larvae of spiruroid species were found in the two tenebrionids (18.1% in P. l. costipennis, 7.8% in H. amaroides), Streptopharagus greenbergi being predominant in both (16.1% and 7.1%, respectively), ahead of Mastophorus muris and Gongylonema type larva. The larval stages of S. greenbergi are described for the first time, and adult worms were obtained experimentally from an infected laboratory rat, allowing the identification of the species. Morphometric measurements of experimental adults match those of adults detected in naturally infected rats on the island. Molecular data for S. greenbergi, and the ITS nucleotide sequence of the genus Streptopharagus are also provided for the first time. After the isolation of S. greenbergi DNA and amplification of the ITS region, the ITS1 of this spirocercid was sequenced and deposited in the GenBank database. Copyright © 2013 Académie des sciences. Published by Elsevier SAS. All rights reserved.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25671714','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25671714"><span>Transient changes in bacterioplankton communities induced by the submarine volcanic eruption of El <span class="hlt">Hierro</span> (Canary Islands).</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Ferrera, Isabel; Arístegui, Javier; González, José M; Montero, María F; Fraile-Nuez, Eugenio; Gasol, Josep M</p> <p>2015-01-01</p> <p>The submarine volcanic eruption occurring near El <span class="hlt">Hierro</span> (Canary Islands) in October 2011 provided a unique opportunity to determine the effects of such events on the microbial populations of the surrounding waters. The birth of a new underwater volcano produced a large plume of vent material detectable from space that led to abrupt changes in the physical-chemical properties of the water column. We combined flow cytometry and 454-pyrosequencing of 16S rRNA gene amplicons (V1-V3 regions for Bacteria and V3-V5 for Archaea) to monitor the area around the volcano through the eruptive and post-eruptive phases (November 2011 to April 2012). Flow cytometric analyses revealed higher abundance and relative activity (expressed as a percentage of high-nucleic acid content cells) of heterotrophic prokaryotes during the eruptive process as compared to post-eruptive stages. Changes observed in populations detectable by flow cytometry were more evident at depths closer to the volcano (~70-200 m), coinciding also with oxygen depletion. Alpha-diversity analyses revealed that species richness (Chao1 index) decreased during the eruptive phase; however, no dramatic changes in community composition were observed. The most abundant taxa during the eruptive phase were similar to those in the post-eruptive stages and to those typically prevalent in oceanic bacterioplankton communities (i.e. the alphaproteobacterial SAR11 group, the Flavobacteriia class of the Bacteroidetes and certain groups of Gammaproteobacteria). Yet, although at low abundance, we also detected the presence of taxa not typically found in bacterioplankton communities such as the Epsilonproteobacteria and members of the candidate division ZB3, particularly during the eruptive stage. These groups are often associated with deep-sea hydrothermal vents or sulfur-rich springs. Both cytometric and sequence analyses showed that once the eruption ceased, evidences of the volcano-induced changes were no longer observed.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4324844','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4324844"><span>Transient Changes in Bacterioplankton Communities Induced by the Submarine Volcanic Eruption of El <span class="hlt">Hierro</span> (Canary Islands)</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Ferrera, Isabel; Arístegui, Javier; González, José M.; Montero, María F.; Fraile-Nuez, Eugenio; Gasol, Josep M.</p> <p>2015-01-01</p> <p>The submarine volcanic eruption occurring near El <span class="hlt">Hierro</span> (Canary Islands) in October 2011 provided a unique opportunity to determine the effects of such events on the microbial populations of the surrounding waters. The birth of a new underwater volcano produced a large plume of vent material detectable from space that led to abrupt changes in the physical-chemical properties of the water column. We combined flow cytometry and 454-pyrosequencing of 16S rRNA gene amplicons (V1–V3 regions for Bacteria and V3–V5 for Archaea) to monitor the area around the volcano through the eruptive and post-eruptive phases (November 2011 to April 2012). Flow cytometric analyses revealed higher abundance and relative activity (expressed as a percentage of high-nucleic acid content cells) of heterotrophic prokaryotes during the eruptive process as compared to post-eruptive stages. Changes observed in populations detectable by flow cytometry were more evident at depths closer to the volcano (~70–200 m), coinciding also with oxygen depletion. Alpha-diversity analyses revealed that species richness (Chao1 index) decreased during the eruptive phase; however, no dramatic changes in community composition were observed. The most abundant taxa during the eruptive phase were similar to those in the post-eruptive stages and to those typically prevalent in oceanic bacterioplankton communities (i.e. the alphaproteobacterial SAR11 group, the Flavobacteriia class of the Bacteroidetes and certain groups of Gammaproteobacteria). Yet, although at low abundance, we also detected the presence of taxa not typically found in bacterioplankton communities such as the Epsilonproteobacteria and members of the candidate division ZB3, particularly during the eruptive stage. These groups are often associated with deep-sea hydrothermal vents or sulfur-rich springs. Both cytometric and sequence analyses showed that once the eruption ceased, evidences of the volcano-induced changes were no longer observed</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29465251','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29465251"><span>Managing iron deficiency and iron deficiency anemia in inflammatory bowel disease. The results of the "Gestiona <span class="hlt">hierro</span>-EII" survey.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Casellas Jordá, Francesc; Vera Mendoza, Isabel; Barreiro-de Acosta, Manuel; Vázquez Morón, Juan María; López Román, Javier; Júdez Gutiérrez, Javier</p> <p>2018-03-01</p> <p>iron deficiency anemia is a common and very relevant manifestation of inflammatory bowel disease (IBD). Although clinical practice guidelines have been published and updated on this subject, the management in the daily practice of this complication is far from optimal. to determine the actual management, needs and limitations of anemia in IBD by means of a survey of gastroenterology specialists. a self-administered telematic survey was carried out between April and May 2017 and was sent to SEPD members. The survey included four sections: participant demographics, monitoring, treatment and limitations/needs. a total of 122 evaluable surveys were received from all Spanish autonomous communities. Iron deficiency anemia is considered as a frequent manifestation of IBD and is monitored in all patients via the measurement of hemoglobin and ferritin. In the case of anemia, the survey respondents found it necessary to rule out the presence of IBD activity. However, only 14.8% prescribed intravenous iron when IBD was active. The required dose of intravenous iron is mainly calculated according to patient needs but only 33.1% of clinicians infused doses of 1 g or more. the "Gestiona <span class="hlt">Hierro</span> EII" survey on the management of anemia in IBD demonstrated a high quality of care, even though some aspects need to be improved. These included the prescription of intravenous iron for patients with disease activity, the use of high-dose intravenous iron and the implementation of algorithms into clinical practice.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015AGUFM.V21C3046O','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015AGUFM.V21C3046O"><span>CO2-SO3-rich (carbonate-sulfate) melt/fluids in the lithosphere beneath El <span class="hlt">Hierro</span>, Canary Islands.</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Oglialoro, E.; Ferrando, S.; Malaspina, N.; Villa, I. M.; Frezzotti, M. L.</p> <p>2015-12-01</p> <p>Mantle xenoliths from the island of El <span class="hlt">Hierro</span>, the youngest of the Canary Islands, have been studied to characterize fluxes of carbon in the lithosphere of an OIB volcanism region. Fifteen xenoliths (4-10 cm in diameter) were collected in a rift lava flow (15-41 ka) at a new xenolith locality in El Julan cliff (S-SW of the island). Peridotites consist of protogranular to porphyroblastic spinel harzburgites, lherzolites, and subordinate dunites. One spinel clinopyroxenite, and one olivine-websterite were also analyzed. Ultramafic xenoliths were classified as HEXO (harzburgite and dunite with exsolved orthopyroxene), HLCO (harzburgite and lherzolite containing orthopyroxene without visible exsolution lamellae), and HTR (transitional harzburgite with exsolved orthopyroxene porphyroclasts, and poikilitic orthopyroxene) following [1]. While HLCO and HTR peridotites contain mostly CO2 fluid inclusions, HEXO peridotites preserve an early association of melt/fluid inclusions containing dominantly carbonate/sulfate/silicate glass, evolving to carbonate/sulfate/phosphate/spinel aggregates, with exsolved CO2 (± carbonates, anhydrite and H2O). Chemical and Raman analyses identify dolomite, Mg-calcite, anhydrite, sulfohalite [Na6(SO4)2FCl] (± other anhydrous and hydrous alkali-sulfates), apatite, and Cr-spinel in the inclusions. Sulfides are noticeably absent. The microstructure and chemical composition of the metasomatic fluids indicate that the peridotites were infiltrated by a carbonate-sulfate-silicate melt/fluid enriched in CO2, H2O, and P. A mantle origin for this fluid is supported by high densities of CO2inclusions (> 1g/cm3), determined by Raman microspectroscopy and cross-checked by microthermometry. Consequently, El Julan peridotites provide the first evidence for liberating oxidized C and S fluxes from the Earth lithosphere in an OIB source region, and suggest that oxidation of sulfide to sulfate can occur during small-degree partial melting of the upper mantle</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA596593','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA596593"><span>The Pros and <span class="hlt">Cons</span> of Army Automation</span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>2007-11-13</p> <p>The Pros and <span class="hlt">Cons</span> of Army Automation 1 Running Head: THE PROS AND <span class="hlt">CONS</span> OF ARMY AUTOMATION The Pros and <span class="hlt">Cons</span> of Army Automation SGM...TITLE AND SUBTITLE The Pros and <span class="hlt">Cons</span> of Army Automation 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT...Prescribed by ANSI Std Z39-18 The Pros and <span class="hlt">Cons</span> of Army Automation 2 Outline I. Introduction (MSG (P) Dostie) II. Manual skills (MSG (P</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2011mwac.meet..T04E','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2011mwac.meet..T04E"><span>Experimental and Computational Studies of Carbonyl Diazide (<span class="hlt">CON</span>6) as a Precursor to Diazirinone (<span class="hlt">CON</span>2)</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Esselman, Brian J.; Amberger, Brent K.; Nolan, Alex M.; Woods, R. Claude; McMahon, R. J.</p> <p>2011-10-01</p> <p>Intrigued by the reported 2005 synthesis of diazirinone (1), we carried out further experimental and theoretical studies aimed at the detailed matrix-isolation and millimeter-wave spectroscopic characterizations of 1. Diazirinone (1) is a peculiar isoconjugate of two very stable molecules and may be of astrochemical interest. Unfortunately, the original reported methods of diazirinone (1) generation did not yield this species, rather its decomposition products. Inspired by a more recent gas phase pyrolysis of <span class="hlt">CON</span>6 (2) to yield <span class="hlt">CON</span>2 (1), we proposed a new method of generating <span class="hlt">CON</span>6 (2) in solution as a precursor of diazirinone (1). This new synthesis may allow us to generate larger quantities of both <span class="hlt">CON</span>6 and <span class="hlt">CON</span>2 for investigation by millimeter-wave spectroscopy. We are able to safely generate carbonyl diazide (2) in sufficient yield from the reaction of triphosgene (3) and tetrabutylammonium azide in diethyl ether. This has allowed us to obtain both matrix-isolation and gas phase IR spectra of carbonyl diazide (2). After purification, it has a gas-phase lifetime that allows samples to be useable for up to several weeks. However, it is a shock-sensitive material that must be handled with care to prevent violent decomposition. In order to provide better mechanistic insight into the decomposition of carbonyl diazide (2) to diazirinone (1), we have engaged in a DFT and ab initio computational study. We have found a pathway between the two species via the triplet acylnitrene, <span class="hlt">CON</span>4, and an oxaziridine <span class="hlt">CON</span>2 species, but not at sufficiently low energies to allow for the trapping and detection of diazirinone (1). Preliminary millimeter-wave spectra have been obtained from several synthesized and purified samples of <span class="hlt">CON</span>6 (2). However, the assignment of the spectra lines has been unexpectedly problematic. We have placed several <span class="hlt">CON</span>6 (2) samples, confirmed by IR spectroscopy at the time of sample loading, into our instrument and obtained two different sets of rotational lines</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015Tectp.642...71T','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015Tectp.642...71T"><span>Multifractal investigation of continuous seismic signal recorded at El <span class="hlt">Hierro</span> volcano (Canary Islands) during the 2011-2012 pre- and eruptive phases</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Telesca, Luciano; Lovallo, Michele; Martì Molist, Joan; López Moreno, Carmen; Abella Meléndez, Rafael</p> <p>2015-02-01</p> <p>The Multifractal Detrended Fluctuation Analysis (MF-DFA) is an effective method that allows detecting multifractality in non-stationary signals. We applied the MF-DFA to the continuous seismic signal recorded at El <span class="hlt">Hierro</span> volcano (Canary Islands), which was affected by a submarine monogenetic eruption in October 2011. We investigated the multifractal properties of the continuous seismic signal before the onset of the eruption and after. We analysed three frames of the signal, one measured before the onset of eruption that occurred on October 10, 2011; and two after, but corresponding to two distinct eruptive episodes, the second one started on November 22, 2011 and lasting until late February 2012. The results obtained show a striking difference in the width of the multifractal spectrum, which is generally used to quantify the multifractal degree of a signal: the multifractal spectra of the signal frames recorded during the eruptive episodes are almost identical and much narrower than that of the signal frame measured before the onset of the eruption. Such difference indicates that the seismic signal recorded during the unrest reflects mostly the fracturing of the host rock under the overpressure exerted by the intruding magma, while that corresponding to the eruptive phases was mostly influenced by the flow of magma through the plumbing system, even some fracturing remains, not being possible to distinguish among the two eruptive episodes in terms of rock fracture mechanics.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_3");'>3</a></li> <li><a href="#" onclick='return showDiv("page_4");'>4</a></li> <li class="active"><span>5</span></li> <li><a href="#" onclick='return showDiv("page_6");'>6</a></li> <li><a href="#" onclick='return showDiv("page_7");'>7</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_5 --> <div id="page_6" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_4");'>4</a></li> <li><a href="#" onclick='return showDiv("page_5");'>5</a></li> <li class="active"><span>6</span></li> <li><a href="#" onclick='return showDiv("page_7");'>7</a></li> <li><a href="#" onclick='return showDiv("page_8");'>8</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="101"> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2012EGUGA..1412251S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2012EGUGA..1412251S"><span>Mafic intrusion remobilising silicic magma under El <span class="hlt">Hierro</span>, Canary Islands</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Sigmarsson, O.; Laporte, D.; Marti, J.; Devouard, B.; Cluzel, N.</p> <p>2012-04-01</p> <p>The 2011 submarine eruption at El <span class="hlt">Hierro</span>, Canary Islands, has produced volcanic bombs that degas at sea surface, boil seawater and sink when cooled and degassed. At the beginning of the eruption white coloured pumices enveloped in darker coloured spatters floated on land. These composite pumices show evidence of magma mingling with folds and undulations of the darker coloured magma within the white pumice suggesting magma mingling in a viscous regime. The white pumice is highly vesicular and resembles foam. Most of the vesicular structure is made of tightly packed, polygonal bubbles of uniform size (˜ 100 μm), suggesting a single event of homogeneous bubble nucleation. An earlier event of heterogeneous bubble nucleation is indicated by the presence of a few large bubbles developed around tiny quartz crystals. Both the darker and lighter coloured pumices are almost aphyric. A few olivine crystals with perfect euhedral morphology occur within the darker part. Rare olivines of same composition are also found in the white pumice glass but then display somewhat rounded outlines and hopper-type structure. Melt inclusions in olivines of the darker pumice are of the same composition as the enveloping mafic glass, whereas olivines in the mixing boundary layer have melt inclusions of less mafic composition. The whole-rock composition and slightly more evolved glass composition are of basanitc and alkali rhyolitic composition (at the limit of the trachyte field) according to the TAS classification. Such rhyolitic compositions are rare in the Canaries. Analyses of residual volatile concentration in the glasses show that the silicic glass is highly degassed (F: 511 ±222; Cl: 202 ±58; S: below detection limit; values in ppm,1SD, n=10), whereas the basanitic glass still has very high halogene concentrations (F: 1354 ±151; Cl: 1026 ±47; S: 362 ±29; 1SD, n=10). In-situ analysis of trace element compositions of the dark glasses reveal typical basanitic compositions with</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014AGUFM.T23C4692B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014AGUFM.T23C4692B"><span>Time-dependent deformation at elevated temperatures in basalt from El <span class="hlt">Hierro</span>, Stromboli and Teide volcanoes</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Benson, P. M.; Fahrner, D.; Harnett, C. E.; Fazio, M.</p> <p>2014-12-01</p> <p>Time dependent deformation describes the process whereby brittle materials deform at a stress level below their short-term material strength (Ss), but over an extended time frame. Although generally well understood in engineering (where it is known as static fatigue or "creep"), knowledge of how rocks creep and fail has wide ramifications in areas as diverse as mine tunnel supports and the long term stability of critically loaded rock slopes. A particular hazard relates to the instability of volcano flanks. A large number of flank collapses are known such as Stromboli (Aeolian islands), Teide, and El <span class="hlt">Hierro</span> (Canary Islands). Collapses on volcanic islands are especially complex as they necessarily involve the combination of active tectonics, heat, and fluids. Not only does the volcanic system generate stresses that reach close to the failure strength of the rocks involved, but when combined with active pore fluid the process of stress corrosion allows the rock mass to deform and creep at stresses far lower than Ss. Despite the obvious geological hazard that edifice failure poses, the phenomenon of creep in volcanic rocks at elevated temperatures has yet to be thoroughly investigated in a well controlled laboratory setting. We present new data using rocks taken from Stromboli, El Heirro and Teide volcanoes in order to better understand the interplay between the fundamental rock mechanics of these basalts and the effects of elevated temperature fluids (activating stress corrosion mechanisms). Experiments were conducted over short (30-60 minute) and long (8-10 hour) time scales. For this, we use the method of Heap et al., (2011) to impose a constant stress (creep) domain deformation monitored via non-contact axial displacement transducers. This is achieved via a conventional triaxial cell to impose shallow conditions of pressure (<25 MPa) and temperature (<200 °C), and equipped with a 3D laboratory seismicity array (known as acoustic emission, AE) to monitor the micro</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA345916','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA345916"><span>West Europe Report No. 2139</span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>1983-05-09</p> <p>Ap-PDP, 2; UCD, 1. Santa Cruz de Tenerife. Voters: 438,618. Seats: 30 (Tenerife, 15; La Palma, 8; Gomera, 4 and <span class="hlt">Hierro</span> , 3). Deputies 28 October 1982...Canaries, have aroused the interest of independent groups that normally operate on the peripheral islands, such as Gomera and <span class="hlt">Hierro</span> . 113 During the...Independent Gomera Electoral Group: Esteban Bethencourt. <span class="hlt">Hierro</span> : PSOE: Jose Francisco Armas. AP-PDP-UL: Manuel Fernandez Gonzalez. PCE: Aurelio Ayala</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/AD1013937','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/AD1013937"><span>Population Parameters of Blainvilles and Cuviers Beaked Whales</span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>2015-09-30</p> <p>cetacean populations. Long-term monitoring of beaked whale populations in El <span class="hlt">Hierro</span> , a nearly pristine habitat far from areas of sonar testing or...marine industry, enables valuable studies of demographic trends and life history dictated mainly by natural parameters. El <span class="hlt">Hierro</span> is in process of...functioning (expected in 2018-2019), it is essential to continue monitoring the populations in El <span class="hlt">Hierro</span> to obtain an uninterrupted long-term dataset of</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA531335','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA531335"><span>Acoustic Detection, Behavior, and Habitat Use of Deep-Diving Odontocetes</span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>2009-09-30</p> <p>of El <span class="hlt">Hierro</span> , and short-finned pilot whales, Globicephela macrorynchus, off the island of Tenerife in the Canary Islands [Aguilar, 2006]). These...in El <span class="hlt">Hierro</span> (Oct. 2008). Key result was an 18 hour DTAG attachment to a Blainville’s beaked whale with contemporary acoustic recordings from a...drifting buoy. • Three 7-day seasonal surveys in El <span class="hlt">Hierro</span> . Methods included passive acoustic monitoring, photo- identification and double visual</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA482696','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA482696"><span>Measuring the Behavior and Response to Sound of Beaked Whales Using Recording Tags</span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>2004-01-01</p> <p>led by Alberto Brito of the University of La Laguna. His team of biology graduate students maintain a field station in the island of El <span class="hlt">Hierro</span> ...in the Canary Island field site of El <span class="hlt">Hierro</span> (Figs. 3, 4). In analyzing identification photos, the Italian group have confirmed sightings of several...specie. The exceptional sighting rate of both species in El <span class="hlt">Hierro</span> makes this one of the densest coastal populations of beaked whales known</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA578413','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA578413"><span>Population Parameters of Beaked Whales</span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>2012-09-30</p> <p>difficult to study. El <span class="hlt">Hierro</span> (Canary Islands) holds resident populations of Blainville’s and Cuvier’s beaked whales in deep waters close to the shore...Field work: We performed two seasonal photoID surveys off El <span class="hlt">Hierro</span> (May and July 2012) focused on the two resident ziphiid species in the waters of...gather ancillary oceanographic data of the waters off El <span class="hlt">Hierro</span> . We obtain measurements of temperature, salinity and nutrient concentration in order</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA606315','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA606315"><span>Acoustic Response and Detection of Marine Mammals Using an Advanced Digital Acoustic Recording Tag(Rev 3)</span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>2007-03-13</p> <p>Victor Gonzalez, University of La Laguna. Fieldwork was supported by University of La Laguna and Governments of El <span class="hlt">Hierro</span> and the Canary Islands...team in El <span class="hlt">Hierro</span> and the Field team in Liguria. Fieldwork support was provided by Universidad de La Laguna (ULL), BluWest, NATO Undersea Research...Center (NURC), and Governments of El <span class="hlt">Hierro</span> and the Canary Islands. Some of Peter Madsen’s work was supported by a Steno Fellowship from the</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA480993','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA480993"><span>Acoustic Detection, Behavior, and Habitat Use of Deep-Diving Odontocetes</span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>2007-01-01</p> <p>Blainville’s beaked whale, Mesoplodon densirostris, and Cuvier’s beaked whale, Ziphius cavirostris, off the island of El <span class="hlt">Hierro</span> in the Canary Islands...vocalizations to compare with the buoy recordings. We will also continue a seasonal photo-identification study of the El <span class="hlt">Hierro</span> beaked whales to build... <span class="hlt">Hierro</span> ), and April 2008 (pilot whales in Tenerife). Due to the late arrival of funds, we opted for a short field season with beaked whales in</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA616471','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA616471"><span>Population Parameters of Blainville’s and Cuvier’s Beaked Whales</span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>2014-09-30</p> <p>waters, they are usually difficult to study. El <span class="hlt">Hierro</span> (Canary Islands) holds resident populations of Blainville’s and Cuvier’s beaked whales in...surveys off El <span class="hlt">Hierro</span> , according to plan. Four of these cruises took place since the last report in September 2013, summing 38 days of fieldwork performed...marks as to be individually recognizable. 3 Publication of results of the ONR funded cetacean research in El <span class="hlt">Hierro</span> in 2014 Peer reviewed</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2012EGUGA..1410243S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2012EGUGA..1410243S"><span>Crustal Deformation During the 2011 Volanic Crisis of El <span class="hlt">Hierro</span>, Canary Islands, Revealed by Continuous GPS Observation</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Sagiya, T.; Barrancos Martinez, J.; Calvo, D.; Padron, E.; Hernandez, G. H.; Hernández, P. A.; Perez Rodriguez, N.; Suárez, J. M. P.</p> <p>2012-04-01</p> <p>Seismo-volcnic activity of El <span class="hlt">Hierro</span> started in the middle of July of 2011 and resulted in the active submarine eruption after October 12 south off La Restinga, the southern tip of the island. We have been operating one continuous GPS site on the island since 2004. Responding to the activity, we quickly installed 5 more GPS sites. Including another site operated by the Canary Islands Cartograhical Service (GRAFCAN) for a cartographic purpose, we have been monitoring 7 GPS sites equipped with dual-frequency receivers. We present the result of our crustal deformation monitoring and the magmatic activity inferred from the deformation data. In accordance with the deformation pattern, we divide the volcanic activity in 2011 into 4 stages. The first stage is from the middle of July to middle of September, during which steady magmatic inflation is estimated at the center of the island. The inflated volume of the first stage is estimated to be about 1.3 X 107 m3 at the depth of about 5km. The second stage, which continued until the first submarine eruption on October 12, is characterized by the accelerated deformation due to the upward as well as southward migration of magma. Additional inflation of about 2.1 X 107 m3 occurred in the depth range of 1-2km. The third stage continued for about 3 weeks after the first submarine eruption. During this stage, submarine eruption continues while no significant surface deformation is observed. It is considered magma supply from a deeper magma chamber continued during this 3 weeks period. Therefore, the total inflation volume during the first two stages gives the minimum estimate for the total magma volume. Since the beginning of November 2011, many GPS sites started subsiding. However, this deflation pattern is quite different from those in the shallow inflation stages. Horizontal deformation during this 4th stage is not significant, implying that deflation is occurring below the moho.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2012EGUGA..1412374M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2012EGUGA..1412374M"><span>Assessing the vulnerability of the evacuation emergency plan: the case of the El <span class="hlt">Hierro</span>, Canary Island, Spain</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Marrero, J. M.; Garcia, A.; Llinares, A.; Lopez, P.; Ortinz, R.</p> <p>2012-04-01</p> <p>On July 17, 2011 an unrest was detected in the El <span class="hlt">Hierro</span> island. A serretian submarine eruption started on October 10th in the southern area of the island, two miles away from La Restinga village. The analysis and interpretation of seismic and deformation data show a large volume of intruded magma. These data also show a high probability of a new vent opening. One of the most complex volcanic hazard scenarios is a new open vent in the El Golfo Valley, in the north slope of the island, where more than 5,000 people live. In this area there are only two possible terrestrial evacuation routes: 1) HI-1 road NE direction, the fastest but most vulnerable one, very near a 1,000 meters height cliff and through a 2 km tunnel with a structural deficiency that had to be closed during high energy periods of seismic activity; and 2) HI-1 road SW direction, a mountain road with many curves, frequent small landslides and fog. The Emergency Plan of the island takes into account the entire evacuation of El Golfo Valley in case of eruption. This process will be carried out by means of an assisted evacuation. The evacuees will be transported to a temporally regrouping shelter outside the valley to organize the transport to Tenerife Island. Only those people who have a second residence or relatives outside the affected area will be able to remain in the island. The evacuation time estimated by authorities for the entire evacuation of El Golfo Valley is of about 4 hours. This is extremely low considering: the complexity of the area; the number of evacuees; the lack of preparedness by the population; and adverse weather conditions. To evaluate the Evacuation Plan vulnerability, a series of evacuation scenarios have been simulated: self-evacuation; assisted evacuation; both terrestrial evacuation routes. The warning time, the response time by the population and the evacuation time have been taken into account.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/CFR-2012-title9-vol2/pdf/CFR-2012-title9-vol2-sec319-300.pdf','CFR2012'); return false;" href="https://www.gpo.gov/fdsys/pkg/CFR-2012-title9-vol2/pdf/CFR-2012-title9-vol2-sec319-300.pdf"><span>9 CFR 319.300 - Chili <span class="hlt">con</span> carne.</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collectionCfr.action?selectedYearFrom=2012&page.go=Go">Code of Federal Regulations, 2012 CFR</a></p> <p></p> <p>2012-01-01</p> <p>... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Chili <span class="hlt">con</span> carne. 319.300 Section 319.300 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY... Products § 319.300 Chili <span class="hlt">con</span> carne. “Chili <span class="hlt">con</span> carne” shall contain not less than 40 percent of meat...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015Tectp.647...33B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015Tectp.647...33B"><span>Three-armed rifts or masked radial pattern of eruptive fissures? The intriguing case of El <span class="hlt">Hierro</span> volcano (Canary Islands)</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Becerril, L.; Galindo, I.; Martí, J.; Gudmundsson, A.</p> <p>2015-04-01</p> <p>Using new surface structural data as well as subsurface structural data obtained from seventeen water galleries, we provide a comprehensive model of the volcano-tectonic evolution of El <span class="hlt">Hierro</span> (Canary Islands). We have identified, measured and analysed more than 1700 volcano-structural elements including vents, eruptive fissures, dykes and faults. The new data provide important information on the main structural patterns of the island and on its stress and strain fields, all of which are crucial for reliable hazard assessments. We conducted temporal and spatial analyses of the main structural elements, focusing on their relative age and association with the three main cycles in the construction of the island: the Tiñor Edifice, the El Golfo-Las Playas Edifice, and the Rift Volcanism. A radial strike distribution, which can be related to constructive episodes, is observed in the on-land structures. A similar strike distribution is seen in the submarine eruptive fissures, which are radial with respect to the centre of the island. However, the volcano-structural elements identified onshore and reflecting the entire volcano-tectonic evolution of the island also show a predominant NE-SW strike, which coincides with the main regional trend of the Canary archipelago as a whole. Two other dominant directions of structural elements, N-S and WNW-ESE, are evident from the establishment of the El Golfo-Las Playas edifice, during the second constructive cycle. We suggest that the radial-striking structures reflect comparatively uniform stress fields during the constructive episodes, mainly conditioned by the combination of overburden pressure, gravitational spreading, and magma-induced stresses in each of the volcanic edifices. By contrast, in the shallower parts of the edifice the NE-SW, N-S and WNW-ESE-striking structures reflect local stress fields related to the formation of mega-landslides and masking the general and regional radial patterns.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5026929','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5026929"><span>Mincle Signaling Promotes <span class="hlt">Con</span>-A Hepatitis</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Greco, Stephanie H.; Torres-Hernandez, Alejandro; Kalabin, Aleksandr; Whiteman, Clint; Rokosh, Rae; Ravirala, Sushma; Ochi, Atsuo; Gutierrez, Johana; Salyana, Muhammad Atif; Mani, Vishnu R.; Nagaraj, Savitha V.; Deutsch, Michael; Seifert, Lena; Daley, Donnele; Barilla, Rocky; Hundeyin, Mautin; Nikifrov, Yuriy; Tejada, Karla; Gelb, Bruce E.; Katz, Steven C.; Miller, George</p> <p>2016-01-01</p> <p>Concanavalin-A (<span class="hlt">Con</span>-A) hepatitis is regarded as a T cell-mediated model of acute liver injury. Mincle is a C-type lectin receptor (CLR) that is critical in the immune response to mycobacteria and fungi, but does not have a well-defined role in pre-clinical models of non-pathogen mediated inflammation. Since Mincle can ligate the cell death ligand SAP130, we postulated that Mincle signaling drives intrahepatic inflammation and liver injury in <span class="hlt">Con</span>-A hepatitis. Acute liver injury was assessed in the murine <span class="hlt">Con</span>-A hepatitis model using C57BL/6, Mincle−/−, and Dectin-1−/− mice. The role of C/EBPβ and HIF-1α signaling was assessed using selective inhibitors. We found that Mincle was highly expressed in hepatic innate inflammatory cells and endothelial cells in both mice and humans. Furthermore, sterile Mincle ligands and Mincle signaling intermediates were increased in the murine liver in <span class="hlt">Con</span>-A hepatitis. Most significantly, Mincle deletion or blockade protected against <span class="hlt">Con</span>-A hepatitis whereas Mincle ligation exacerbated disease. Bone marrow chimeric and adoptive transfer experiments suggested that Mincle signaling in infiltrating myeloid cells dictates disease phenotype. Conversely, signaling via other CLRs did not alter disease course. Mechanistically, we found that Mincle blockade decreased the NF-κβ related signaling intermediates, C/EBPβ and HIF-1α, both of which are necessary in macrophage-mediated inflammatory responses. Accordingly, Mincle deletion lowered production of nitrites in <span class="hlt">Con</span>-A hepatitis and inhibition of both C/EBPβ and HIF1-α reduced the severity of liver disease. Our work implicates a novel innate immune driver of <span class="hlt">Con</span>-A hepatitis and, more broadly, suggests a potential role for Mincle in diseases governed by sterile inflammation. PMID:27559045</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27559045','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27559045"><span>Mincle Signaling Promotes <span class="hlt">Con</span> A Hepatitis.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Greco, Stephanie H; Torres-Hernandez, Alejandro; Kalabin, Aleksandr; Whiteman, Clint; Rokosh, Rae; Ravirala, Sushma; Ochi, Atsuo; Gutierrez, Johana; Salyana, Muhammad Atif; Mani, Vishnu R; Nagaraj, Savitha V; Deutsch, Michael; Seifert, Lena; Daley, Donnele; Barilla, Rocky; Hundeyin, Mautin; Nikifrov, Yuriy; Tejada, Karla; Gelb, Bruce E; Katz, Steven C; Miller, George</p> <p>2016-10-01</p> <p><span class="hlt">Con</span> A hepatitis is regarded as a T cell-mediated model of acute liver injury. Mincle is a C-type lectin receptor that is critical in the immune response to mycobacteria and fungi but does not have a well-defined role in preclinical models of non-pathogen-mediated inflammation. Because Mincle can ligate the cell death ligand SAP130, we postulated that Mincle signaling drives intrahepatic inflammation and liver injury in <span class="hlt">Con</span> A hepatitis. Acute liver injury was assessed in the murine <span class="hlt">Con</span> A hepatitis model using C57BL/6, Mincle(-/-), and Dectin-1(-/-) mice. The role of C/EBPβ and hypoxia-inducible factor-1α (HIF-1α) signaling was assessed using selective inhibitors. We found that Mincle was highly expressed in hepatic innate inflammatory cells and endothelial cells in both mice and humans. Furthermore, sterile Mincle ligands and Mincle signaling intermediates were increased in the murine liver in <span class="hlt">Con</span> A hepatitis. Most significantly, Mincle deletion or blockade protected against <span class="hlt">Con</span> A hepatitis, whereas Mincle ligation exacerbated disease. Bone marrow chimeric and adoptive transfer experiments suggested that Mincle signaling in infiltrating myeloid cells dictates disease phenotype. Conversely, signaling via other C-type lectin receptors did not alter disease course. Mechanistically, we found that Mincle blockade decreased the NF-κβ-related signaling intermediates C/EBPβ and HIF-1α, both of which are necessary in macrophage-mediated inflammatory responses. Accordingly, Mincle deletion lowered production of nitrites in <span class="hlt">Con</span> A hepatitis and inhibition of both C/EBPβ and HIF-1α reduced the severity of liver disease. Our work implicates a novel innate immune driver of <span class="hlt">Con</span> A hepatitis and, more broadly, suggests a potential role for Mincle in diseases governed by sterile inflammation. Copyright © 2016 by The American Association of Immunologists, Inc.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA533030','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA533030"><span>Acoustic Detection, Behavior, and Habitat Use of Deep-Diving Odontocetes</span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>2008-09-30</p> <p>Rev. 8-98) Prescribed by ANSI Std Z39-18 off the island of El <span class="hlt">Hierro</span> , and short-finned pilot whales, Globicephela macrorynchus, off the island of...El <span class="hlt">Hierro</span> focused on beaked whales. A field team of 8-10 people staffed a shore visual station and two small boats for a total of 47 at-sea days in...increases our holdings to 11 tags from El <span class="hlt">Hierro</span> on this little-known species. A 21’ observation vessel, made available to the program at no cost by the</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA193744','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA193744"><span>Women in Combat Pros and <span class="hlt">Cons</span></span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>1988-04-01</p> <p>and <span class="hlt">Cons</span> . Major Thomas H. Cecil 88-0490 "--"insights into tomorrou,"’ ..v- A A 0 PtY-i f(.> i’I,-:::x:’~ --pcr~ j.~ ~~* --. -- iiV • DISCLAIMER The...k. r- r,’ I’. REPORT NUMBER 88-0490 TITLE WOMEN IN COMBAT-PROS AND <span class="hlt">CONS</span> AUTHOR(S) MAJOR THOMAS H. CEC-IL, USAF -% FACULTY ADVISOR CH, LT COL DAVID W...NUMBERS 11 TITLE (include Security Classification) WOMEN IN COMBAT--PROS AND <span class="hlt">CONS</span> 12. PERSON4AL AUTHOR(S) Cecil, Thomas H1., Major, USAF 9a YýOF REPORT</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4138816','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4138816"><span>Ependimoma myxopapilar sacro gigante <span class="hlt">con</span> osteolisis</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Ajler, Pablo; Landriel, Federico; Goldschmidt, Ezequiel; Campero, Álvaro; Yampolsky, Claudio</p> <p>2014-01-01</p> <p>Objetivo: la presentación de un caso de una paciente <span class="hlt">con</span> un ependimoma sacro <span class="hlt">con</span> extensa infiltración y destrucción ósea local. Descripción del caso: una mujer de 53 años acudió a la consulta por dolor lumbosacro y alteraciones sensitivas perineales y esfinterianas. La imágenes por Resonancia Magnética (IRM) y la Tomografía Axial Computada (TAC) mostraron una lesión expansiva gigante a nivel S2-S4 <span class="hlt">con</span> extensa osteólisis e invasión de tejidos adyacentes. Se realizó una exéresis tumoral completa <span class="hlt">con</span> mejoría del estatus funcional. La anatomía patológica informó ependimoma mixopapilar. Discusión: la extensión de la resección quirúrgica es el mejor predictor de buen pronóstico. El tratamiento radiante se reserva como opción adyuvante para las resecciones incompletas y recidiva tumoral. La quimioterapia sólo debería utilizarse en casos en que la cirugía y la radioterapia estén contraindicadas. Conclusión: Los ependimomas mixopapilares sacros <span class="hlt">con</span> destrucción ósea y presentación intra y extradural son muy infrecuentes y deben ser tenidos en cuenta entre los diagnósticos diferenciales preoperatorios. Su resección total, siempre que sea posible, es la mejor alternativa terapéutica. PMID:25165615</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014EGUGA..1614269S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014EGUGA..1614269S"><span>Probabilistic approach to decision making under uncertainty during volcanic crises. Retrospective analysis of the 2011 eruption of El <span class="hlt">Hierro</span>, in the Canary Islands</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Sobradelo, Rosa; Martí, Joan; Kilburn, Christopher; López, Carmen</p> <p>2014-05-01</p> <p>Understanding the potential evolution of a volcanic crisis is crucial to improving the design of effective mitigation strategies. This is especially the case for volcanoes close to densely-populated regions, where inappropriate decisions may trigger widespread loss of life, economic disruption and public distress. An outstanding goal for improving the management of volcanic crises, therefore, is to develop objective, real-time methodologies for evaluating how an emergency will develop and how scientists communicate with decision makers. Here we present a new model BADEMO (Bayesian Decision Model) that applies a general and flexible, probabilistic approach to managing volcanic crises. The model combines the hazard and risk factors that decision makers need for a holistic analysis of a volcanic crisis. These factors include eruption scenarios and their probabilities of occurrence, the vulnerability of populations and their activities, and the costs of false alarms and failed forecasts. The model can be implemented before an emergency, to identify actions for reducing the vulnerability of a district; during an emergency, to identify the optimum mitigating actions and how these may change as new information is obtained; and after an emergency, to assess the effectiveness of a mitigating response and, from the results, to improve strategies before another crisis occurs. As illustrated by a retrospective analysis of the 2011 eruption of El <span class="hlt">Hierro</span>, in the Canary Islands, BADEMO provides the basis for quantifying the uncertainty associated with each recommended action as an emergency evolves, and serves as a mechanism for improving communications between scientists and decision makers.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_4");'>4</a></li> <li><a href="#" onclick='return showDiv("page_5");'>5</a></li> <li class="active"><span>6</span></li> <li><a href="#" onclick='return showDiv("page_7");'>7</a></li> <li><a href="#" onclick='return showDiv("page_8");'>8</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_6 --> <div id="page_7" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_5");'>5</a></li> <li><a href="#" onclick='return showDiv("page_6");'>6</a></li> <li class="active"><span>7</span></li> <li><a href="#" onclick='return showDiv("page_8");'>8</a></li> <li><a href="#" onclick='return showDiv("page_9");'>9</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="121"> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4138825','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4138825"><span>Planificación Neuroquirúrgica <span class="hlt">con</span> Software Osirix</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Jaimovich, Sebastián Gastón; Guevara, Martin; Pampin, Sergio; Jaimovich, Roberto; Gardella, Javier Luis</p> <p>2014-01-01</p> <p>Introducción: La individualidad anatómica es clave para reducir el trauma quirúrgico y obtener un mejor resultado. Actualmente, el avance en las neuroimágenes ha permitido objetivar esa individualidad anatómica, permitiendo planificar la intervención quirúrgica. <span class="hlt">Con</span> este objetivo, presentamos nuestra experiencia <span class="hlt">con</span> el software Osirix. Descripción de la técnica: Se presentan 3 casos ejemplificadores de 40 realizados. Caso 1: Paciente <span class="hlt">con</span> meningioma de la convexidad parasagital izquierda en área premotora; Caso 2: Paciente <span class="hlt">con</span> macroadenoma hipofisario, operada previamente por vía transeptoesfenoidal en otra institución <span class="hlt">con</span> una resección parcial; Caso 3: Paciente <span class="hlt">con</span> lesiones en pedúnculo cerebeloso medio bilateral. Se realizó la planificación prequirúrgica <span class="hlt">con</span> el software OsiriX, fusionando y reconstruyendo en 3D las imágenes de TC e IRM, para analizar relaciones anatómicas, medir distancias, coordenadas y trayectorias, entre otras funciones. Discusión: El software OsiriX de acceso libre y gratuito permite al cirujano, mediante la fusión y reconstrucción en 3D de imágenes, analizar la anatomía individual del paciente y planificar de forma rápida, simple, segura y económica cirugías de alta complejidad. En el Caso 1 se pudo analizar las relaciones del tumor <span class="hlt">con</span> las estructuras adyacentes para minimizar el abordaje. En el Caso 2 permitió comprender la anatomía post-operatoria previa del paciente, para determinar la trayectoria del abordaje transnasal endoscópico y la necesidad de ampliar su exposición, logrando la resección tumoral completa. En el Caso 3 permitió obtener las coordenadas estereotáxicas y trayectoria de una lesión sin representación tomográfica. Conclusión: En casos de no contar <span class="hlt">con</span> costosos sistemas de neuronavegación o estereotáxia el software OsiriX es una alternativa a la hora de planificar la cirugía, <span class="hlt">con</span> el objetivo de disminuir el trauma y la morbilidad operatoria. PMID:25165617</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA299337','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA299337"><span>Pros and <span class="hlt">Cons</span> of International Weapons Procurement Collaboration.</span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>1995-01-01</p> <p>ad- vanced U.S. industry. Greater risk of cost growth and schedule slippage. Pro: U.S. and partners share common equip- ment. <span class="hlt">Con</span> : U.S. require...Mark A., 1947- Pros and <span class="hlt">cons</span> of international weapons procurement collaboration / Mark Lorell, Julia Lowell, p. cm "Prepared for the Office...one/ <span class="hlt">Cons</span> of International Weapons Procurement Collaboration Mark Lorell Julia Lowell National Defense Research Institute Prepared for the</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA531853','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA531853"><span>Development and Validation of a Mobile, Autonomous, Broadband Passive Acoustic Monitoring System for Marine Mammals</span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>2009-09-30</p> <p>will take place off the island of El <span class="hlt">Hierro</span> in the Canary Islands, a site with coastal resident populations of Blainville’s beaked whale, Mesoplodon...whales off El <span class="hlt">Hierro</span> , Canary Islands” European Research on Cetaceans 22nd, Holland, April, 2008. [non-refereed] Beedholm K., Madsen P., Johnson M</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA598752','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA598752"><span>Development and Validation of a Mobile, Autonomous, Broadband Passive Acoustic Monitoring System for Marine Mammals</span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>2011-09-30</p> <p>For beaked whales, field testing will take place off the island of El <span class="hlt">Hierro</span> in the Canary Islands, a site with coastal resident populations of...beaked whales off El <span class="hlt">Hierro</span> , Canary Islands,” European Research on Cetaceans 22nd. Holland, April, 2008. Baumgartner, M. F., and S. E. Mussoline</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/CFR-2013-title9-vol2/pdf/CFR-2013-title9-vol2-sec319-301.pdf','CFR2013'); return false;" href="https://www.gpo.gov/fdsys/pkg/CFR-2013-title9-vol2/pdf/CFR-2013-title9-vol2-sec319-301.pdf"><span>9 CFR 319.301 - Chili <span class="hlt">con</span> carne with beans.</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collectionCfr.action?selectedYearFrom=2013&page.go=Go">Code of Federal Regulations, 2013 CFR</a></p> <p></p> <p>2013-01-01</p> <p>... 9 Animals and Animal Products 2 2013-01-01 2013-01-01 false Chili <span class="hlt">con</span> carne with beans. 319.301 Section 319.301 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... Dehydrated Meat Food Products § 319.301 Chili <span class="hlt">con</span> carne with beans. Chili <span class="hlt">con</span> carne with beans shall contain...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/CFR-2014-title9-vol2/pdf/CFR-2014-title9-vol2-sec319-301.pdf','CFR2014'); return false;" href="https://www.gpo.gov/fdsys/pkg/CFR-2014-title9-vol2/pdf/CFR-2014-title9-vol2-sec319-301.pdf"><span>9 CFR 319.301 - Chili <span class="hlt">con</span> carne with beans.</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collectionCfr.action?selectedYearFrom=2014&page.go=Go">Code of Federal Regulations, 2014 CFR</a></p> <p></p> <p>2014-01-01</p> <p>... 9 Animals and Animal Products 2 2014-01-01 2014-01-01 false Chili <span class="hlt">con</span> carne with beans. 319.301 Section 319.301 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... Dehydrated Meat Food Products § 319.301 Chili <span class="hlt">con</span> carne with beans. Chili <span class="hlt">con</span> carne with beans shall contain...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/CFR-2011-title9-vol2/pdf/CFR-2011-title9-vol2-sec319-301.pdf','CFR2011'); return false;" href="https://www.gpo.gov/fdsys/pkg/CFR-2011-title9-vol2/pdf/CFR-2011-title9-vol2-sec319-301.pdf"><span>9 CFR 319.301 - Chili <span class="hlt">con</span> carne with beans.</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collectionCfr.action?selectedYearFrom=2011&page.go=Go">Code of Federal Regulations, 2011 CFR</a></p> <p></p> <p>2011-01-01</p> <p>... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Chili <span class="hlt">con</span> carne with beans. 319.301 Section 319.301 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... Dehydrated Meat Food Products § 319.301 Chili <span class="hlt">con</span> carne with beans. Chili <span class="hlt">con</span> carne with beans shall contain...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/CFR-2012-title9-vol2/pdf/CFR-2012-title9-vol2-sec319-301.pdf','CFR2012'); return false;" href="https://www.gpo.gov/fdsys/pkg/CFR-2012-title9-vol2/pdf/CFR-2012-title9-vol2-sec319-301.pdf"><span>9 CFR 319.301 - Chili <span class="hlt">con</span> carne with beans.</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collectionCfr.action?selectedYearFrom=2012&page.go=Go">Code of Federal Regulations, 2012 CFR</a></p> <p></p> <p>2012-01-01</p> <p>... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Chili <span class="hlt">con</span> carne with beans. 319.301 Section 319.301 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... Dehydrated Meat Food Products § 319.301 Chili <span class="hlt">con</span> carne with beans. Chili <span class="hlt">con</span> carne with beans shall contain...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/CFR-2010-title9-vol2/pdf/CFR-2010-title9-vol2-sec319-301.pdf','CFR'); return false;" href="https://www.gpo.gov/fdsys/pkg/CFR-2010-title9-vol2/pdf/CFR-2010-title9-vol2-sec319-301.pdf"><span>9 CFR 319.301 - Chili <span class="hlt">con</span> carne with beans.</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collectionCfr.action?selectedYearFrom=2010&page.go=Go">Code of Federal Regulations, 2010 CFR</a></p> <p></p> <p>2010-01-01</p> <p>... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Chili <span class="hlt">con</span> carne with beans. 319.301 Section 319.301 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... Dehydrated Meat Food Products § 319.301 Chili <span class="hlt">con</span> carne with beans. Chili <span class="hlt">con</span> carne with beans shall contain...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA374015','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA374015"><span>Translations on Latin America, Number 1657</span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>1977-06-01</p> <p>Text] The 17th of last March, Industria del <span class="hlt">Hierro</span> , S.A. [Iron Industries] delivered through its mechanical division-8 land rigs for drilling...design of this equipment allows it to be re-installed in only 3 days. Industria del <span class="hlt">Hierro</span> was established in the city of Queretaro in 1963, with</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA495629','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA495629"><span>Bioavailability of Allelochemicals in Soil</span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>2008-02-27</p> <p>knapweed species has been noted (Goslee et at., 2001; Grant et al., 2003; <span class="hlt">Hierro</span> and Callaway, 2003). Yet, very little is known about the sorption of...Environmental Science & Technology 31:321-326. <span class="hlt">Hierro</span> , J.L., and R.M. Callaway. 2003. Allelopathy and exotic plant invasion. Plant and Soil 256:29-39</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA441195','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA441195"><span>Development and Field testing of the DTAG for Deep-Diving Odontocetes</span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>2005-01-12</p> <p>34Resident and reproductive populations of beaked whales in El <span class="hlt">Hierro</span> , Canary Islands", European Research on Cetaceans 19th, France, April 2005. Aguilar... <span class="hlt">Hierro</span> (Canary Islands)", European Research on Cetaceans 18th, Sweden, 2004. Tregenza N.J.C., Johnson M., Aguilar de Soto N., "Automated detection of</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2012EGUGA..14.6092S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2012EGUGA..14.6092S"><span>Volcanic hazard assessment for the Canary Islands (Spain) using extreme value theory, and the recent volcanic eruption of El <span class="hlt">Hierro</span></span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Sobradelo, R.; Martí, J.; Mendoza-Rosas, A. T.; Gómez, G.</p> <p>2012-04-01</p> <p>The Canary Islands are an active volcanic region densely populated and visited by several millions of tourists every year. Nearly twenty eruptions have been reported through written chronicles in the last 600 years, suggesting that the probability of a new eruption in the near future is far from zero. This shows the importance of assessing and monitoring the volcanic hazard of the region in order to reduce and manage its potential volcanic risk, and ultimately contribute to the design of appropriate preparedness plans. Hence, the probabilistic analysis of the volcanic eruption time series for the Canary Islands is an essential step for the assessment of volcanic hazard and risk in the area. Such a series describes complex processes involving different types of eruptions over different time scales. Here we propose a statistical method for calculating the probabilities of future eruptions which is most appropriate given the nature of the documented historical eruptive data. We first characterise the eruptions by their magnitudes, and then carry out a preliminary analysis of the data to establish the requirements for the statistical method. Past studies in eruptive time series used conventional statistics and treated the series as an homogeneous process. In this paper, we will use a method that accounts for the time-dependence of the series and includes rare or extreme events, in the form of few data of large eruptions, since these data require special methods of analysis. Hence, we will use a statistical method from extreme value theory. In particular, we will apply a non-homogeneous Poisson process to the historical eruptive data of the Canary Islands to estimate the probability of having at least one volcanic event of a magnitude greater than one in the upcoming years. Shortly after the publication of this method an eruption in the island of El <span class="hlt">Hierro</span> took place for the first time in historical times, supporting our method and contributing towards the validation of</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA551851','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA551851"><span>Reliability-Limiting Defects in GaN/AlGaN High Electron Mobility Transistors</span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>2011-12-01</p> <p>GaN grown by plasma-assisted molecular beam epitaxy”, Appl. Phys. Lett., vol. 77, no. 18, pp. 2885- 2887, 2000. [24] A. <span class="hlt">Hierro</span> , A. R. Arehart, B...defects and impurities: Applications to III-nitrides”, J. Appl. Phys., vol. 95, pp.3851-3879, 2004. [43] A. <span class="hlt">Hierro</span> , S. A. Ringel, M. Hansen, J. S</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA541592','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA541592"><span>Development and Validation of a Mobile, Autonomous, Broadband Passive Acoustic Monitoring System for Marine Mammals</span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>2010-09-30</p> <p>after each trial. For beaked whales, field testing will take place off the island of El <span class="hlt">Hierro</span> in the Canary Islands, a site with coastal resident...Johnson, M., “Coastal habitat use by Cuvier´s and Blainville´s beaked whales off El <span class="hlt">Hierro</span> , Canary Islands” European Research on Cetaceans 22nd</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1998BAAA...42...58G','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1998BAAA...42...58G"><span>Galaxias australes <span class="hlt">con</span> núcleo doble</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Gimeno, G.; Díaz, R.; Carranza, G.</p> <p></p> <p>Se estudia una muestra de galaxias australes <span class="hlt">con</span> núcleo doble a partir de una búsqueda extensiva en la literatura. Se analizan las características morfológicas, fotométricas y espectroscópicas de la muestra. Para algunas galaxias se han realizado observaciones <span class="hlt">con</span> el espectrógrafo multifunción (EMF) de la Estación Astrofísica de Bosque Alegre a partir de las cuales se determinaron parámetros cinemáticos.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA482208','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA482208"><span>Current Collapse Induced in AlGaN/GaN High-Electron-Mobility Transistors by Bias Stress</span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>2003-08-25</p> <p>structure where the traps causing current collapse can be passivated by forming H-defect complexes. <span class="hlt">Hierro</span> et al.7 have shown, for example, that deep...Lett. 75, 4016 ~1999!. 7 A. <span class="hlt">Hierro</span> , S. A. Ringel, M. Hansen, J. S. Speck, U. K. Mishra, and S. P. DenBaars, Appl. Phys. Lett. 77, 1499 ~2000!. 8 S. J</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA533837','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA533837"><span>Development and Validation of a Mobile, Autonomous, Broadband Passive Acoustic Monitoring System for Marine Mammals</span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>2008-09-30</p> <p>take place off the island of El <span class="hlt">Hierro</span> in the Canary Islands, a site with coastal resident populations of Blainville’s beaked whale, Mesoplodon...M., “Coastal habitat use by Cuvier´s and Blainville´s beaked whales off El <span class="hlt">Hierro</span> , Canary Islands” European Research on Cetaceans 22nd, Holland, April, 2008. [non-refereed] 5</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA285009','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA285009"><span>The Procurement of Non Developmental Items: Pros and <span class="hlt">Cons</span></span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>1994-09-01</p> <p>commercial way of procurement will bring more advantages than disadvantages to DOD. The list of the pros greatly outweighs the <span class="hlt">cons</span> . There is practically...AD-A285 009 MH PROCUREMENT OF NON DEVELOPMENTAL ITEMS: PROS AND <span class="hlt">CONS</span> THES IS Giorgio Scappaticci. Lt. Col., Italian Air Force AFIT/GLMILALj94S-3 I...PROS AND <span class="hlt">CONS</span> U;narmou,.ced 0 Justification THESIS Giorgio Scappaticci, Lt. Col., Italian Air Force Dist’ibution f Availability Codes AFIT/GLM/LAL</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28369168','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28369168"><span><span class="hlt">Con</span>Kit: a python interface to contact predictions.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Simkovic, Felix; Thomas, Jens M H; Rigden, Daniel J</p> <p>2017-07-15</p> <p>Recent advances in protein residue contact prediction algorithms have led to the emergence of many new methods and a variety of file formats. We present <span class="hlt">Con</span>Kit , an open source, modular and extensible Python interface which allows facile conversion between formats and provides an interface to analyses of sequence alignments and sets of contact predictions. <span class="hlt">Con</span>Kit is available via the Python Package Index. The documentation can be found at http://www.conkit.org . <span class="hlt">Con</span>Kit is licensed under the BSD 3-Clause. hlfsimko@liverpool.ac.uk or drigden@liverpool.ac.uk. Supplementary data are available at Bioinformatics online. © The Author(s) 2017. Published by Oxford University Press.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_5");'>5</a></li> <li><a href="#" onclick='return showDiv("page_6");'>6</a></li> <li class="active"><span>7</span></li> <li><a href="#" onclick='return showDiv("page_8");'>8</a></li> <li><a href="#" onclick='return showDiv("page_9");'>9</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_7 --> <div id="page_8" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_6");'>6</a></li> <li><a href="#" onclick='return showDiv("page_7");'>7</a></li> <li class="active"><span>8</span></li> <li><a href="#" onclick='return showDiv("page_9");'>9</a></li> <li><a href="#" onclick='return showDiv("page_10");'>10</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="141"> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018AAS...23144410S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018AAS...23144410S"><span>ComSci<span class="hlt">Con</span>: The Communicating Science Workshop for Graduate Students</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Sanders, Nathan; Drout, Maria; Kohler, Susanna; Cook, Ben; ComSciCon Leadership Team</p> <p>2018-01-01</p> <p>ComSci<span class="hlt">Con</span> (comscicon.com) is a national workshop series organized by graduate students, for graduate students, focused on leadership and training in science communication. Our goal is to empower young scientists to become leaders in their field, propagating appreciation and understanding of research results to broad and diverse audiences. ComSci<span class="hlt">Con</span> attendees meet and interact with professional communicators, build lasting networks with graduate students in all fields of science and engineering from around the country, and write and publish original works. ComSci<span class="hlt">Con</span> consists of both a flagship national conference series run annually for future leaders in science communication, and a series of regional and specialized workshops organized by ComSci<span class="hlt">Con</span> alumni nationwide. We routinely receive over 1000 applications for 50 spots in our national workshop. Since its founding in 2012, over 300 STEM graduate students have participated in the national workshop, and 23 local spin-off workshops have been organized in 10 different locations throughout the country. This year, ComSci<span class="hlt">Con</span> is working to grow as a self-sustaining organization by launching as an independent 501(c)(3) non-profit. In this poster we will discuss the ComSci<span class="hlt">Con</span> program and methods, our results to date, potential future collaborations between ComSci<span class="hlt">Con</span> and AAS, and how you can become involved.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2003BAAA...46...95F','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2003BAAA...46...95F"><span>Trazando la materia oscura <span class="hlt">con</span> cúmulos globulares</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Forte, J. C.</p> <p></p> <p>Se describe la estrategia adoptada para mapear la distribución de materia oscura y bariónica en galaxias elípticas cuyos cúmulos globulares están siendo observados <span class="hlt">con</span> los telescopios VLT y Gemini. Se ejemplifican los resultados <span class="hlt">con</span> los datos obtenidos en el cúmulo de Fornax.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28937838','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28937838"><span>Protein Supplements: Pros and <span class="hlt">Cons</span>.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Samal, Jay Rabindra Kumar; Samal, Indira R</p> <p>2018-05-04</p> <p>To provide a comprehensive analysis of the literature examining the pros and <span class="hlt">cons</span> of protein supplementation, various articles on protein supplementation were obtained from Google Scholar, PubMed, and National Center for Biotechnology Information. Over the past few years, protein supplementation has become commonplace for gym-goers as well as for the public. A large segment of the general population relies on protein supplementation for meal replacement, weight reduction, and purported health benefits. These protein supplements have varying pros and <span class="hlt">cons</span> associated with them, which are often overlooked by the public. This review aims to assimilate existing studies and form a consensus regarding the benefits and disadvantages of protein supplementation. The purported health benefits of protein supplementation have led to overuse by both adults and adolescents. Although the pros and <span class="hlt">cons</span> of protein supplementation is a widely debated topic, not many studies have been conducted regarding the same. The few studies that exist either provide insufficient evidence or have not employed proper conditions for the conduct of the tests. It should be considered that protein supplements are processed materials and often do not contain other essential nutrients required for the sustenance of a healthy lifestyle. It is suggested that the required protein intake should be obtained from natural food sources and protein supplementation should be resorted to only if sufficient protein is not available in the normal diet.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA602460','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA602460"><span>Laterally-Biased Quantum IR Detectors</span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>2013-10-23</p> <p>Rocío San-Román, Adrián <span class="hlt">Hierro</span> , Journal of Crystal Growth 323, (2011), 496-500. [3] Semiconductor Devices: Physics and Technology 2nd Ed., S.M. Sze...6] “Laterally biased double quantum well IR detector fabricated by MBE regrowth”, Álvaro Guzmán, Rocío San-Román, Adrián <span class="hlt">Hierro</span> , 16th</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29771275','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29771275"><span><span class="hlt">Con</span>SpeciFix: Classifying prokaryotic species based on gene flow.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Bobay, Louis-Marie; Ellis, Brian Shin-Hua; Ochman, Howard</p> <p>2018-05-16</p> <p>Classification of prokaryotic species is usually based on sequence similarity thresholds, which are easy to apply but lack a biologically-relevant foundation. Here, we present <span class="hlt">Con</span>SpeciFix, a program that classifies prokaryotes into species using criteria set forth by the Biological Species Concept, thereby unifying species definition in all domains of life. <span class="hlt">Con</span>SpeciFix's webserver is freely available at www.conspecifix.com. The local version of the program can be freely downloaded from https://github.com/Bobay-Ochman/<span class="hlt">Con</span>SpeciFix. <span class="hlt">Con</span>SpeciFix is written in Python 2.7 and requires the following dependencies: Usearch, MCL, MAFFT and RAxML. ljbobay@uncg.edu.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://eric.ed.gov/?q=men+AND+game&pg=7&id=EJ225097','ERIC'); return false;" href="https://eric.ed.gov/?q=men+AND+game&pg=7&id=EJ225097"><span>Games <span class="hlt">Con</span> Men Play: The Semiosis of Deceptive Interaction.</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Hankiss, Agnes</p> <p>1980-01-01</p> <p>Analyzes some of the most frequent deceptive interactions as rendered through case histories of male <span class="hlt">con</span> artists and their victims taken from police records. Discusses the recurrent elements in both the <span class="hlt">con</span>-games strategies and victims' way of interpreting those strategies. (JMF)</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://cfpub.epa.gov/si/si_public_record_report.cfm?dirEntryId=247658&Lab=NERL&keyword=health+AND+physics&actType=&TIMSType=+&TIMSSubTypeID=&DEID=&epaNumber=&ntisID=&archiveStatus=Both&ombCat=Any&dateBeginCreated=&dateEndCreated=&dateBeginPublishedPresented=&dateEndPublishedPresented=&dateBeginUpdated=&dateEndUpdated=&dateBeginCompleted=&dateEndCompleted=&personID=&role=Any&journalID=&publisherID=&sortBy=revisionDate&count=50','EPA-EIMS'); return false;" href="https://cfpub.epa.gov/si/si_public_record_report.cfm?dirEntryId=247658&Lab=NERL&keyword=health+AND+physics&actType=&TIMSType=+&TIMSSubTypeID=&DEID=&epaNumber=&ntisID=&archiveStatus=Both&ombCat=Any&dateBeginCreated=&dateEndCreated=&dateBeginPublishedPresented=&dateEndPublishedPresented=&dateBeginUpdated=&dateEndUpdated=&dateBeginCompleted=&dateEndCompleted=&personID=&role=Any&journalID=&publisherID=&sortBy=revisionDate&count=50"><span>Breath Analysis Science at Pitt<span class="hlt">Con</span> 2012, Orlando, Florida</span></a></p> <p><a target="_blank" href="http://oaspub.epa.gov/eims/query.page">EPA Science Inventory</a></p> <p></p> <p></p> <p>Breath analysis science was featured in three organized sessions at this year’s Pittsburgh Conference and Exposition, or ‘Pitt<span class="hlt">Con</span> 2012’ (http://www.pittcon.org/). As described in previous meeting reports, Pitt<span class="hlt">Con</span> is one of the largest international conferences for analytical chem...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA534545','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA534545"><span>Collaborative Research and Development (CR&D). Task Order 0036: Physical and Chemical Processes of Operating Electronic Devices</span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>2006-09-01</p> <p>actually seen. A. <span class="hlt">Hierro</span> , … S. A. Ringel et al., Phys. Stat. Sol (b) 228, 937 (2001). Ohio State U. Use DLTS and DLOS (Deep Level Optical Spectroscopy...to threading dislocations. Also see A. <span class="hlt">Hierro</span> et al., APL 76, 3064 (2000), where traps at EC-ET=0.58-0.62, 1.35, 2.57-2.64, 3.22eV are seen in GaN</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014E%26PSL.403..456O','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014E%26PSL.403..456O"><span>Comment on “Identification of the subsurface sulfide bodies responsible for acidity in Río Tinto source water, Spain” by Gómez-Ortiz et al. (Earth Planet. Sci. Lett. 391 (2014) 36-41)</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Olías, Manuel; Nieto, José Miguel</p> <p>2014-10-01</p> <p>The source of the Río Tinto (SW Spain) is currently located close to the Peña de <span class="hlt">Hierro</span> mine, where it receives the first acidic waters. A few kilometers south, the river crosses the Río Tinto mines, a supergiant massive sulfide deposit that is much more important than those of Peña de <span class="hlt">Hierro</span>, and the acid pollutant contributions to the river increase by orders of magnitude.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://images.nasa.gov/#/details-GSFC_20171208_Archive_e001276.html','SCIGOVIMAGE-NASA'); return false;" href="https://images.nasa.gov/#/details-GSFC_20171208_Archive_e001276.html"><span>Canary Islands</span></a></p> <p><a target="_blank" href="https://images.nasa.gov/">NASA Image and Video Library</a></p> <p></p> <p>2013-12-30</p> <p>On December 10, 2013 the Moderate Resolution Imaging Spectroradiometer (MODIS) aboard NASA’s Terra satellite flew across the central Atlantic Ocean and captured a true-color image of the Canary Islands. Lying off of the coast of Western Sahara and Morocco, the islands were created by successive submarine volcanic eruptions which raised the ocean floor vertically until some of land rose above sea level. The oldest islands lie in the east and the youngest in the west. From east to west, the major islands seen in this image are: Lanzarote, Fuerteventura, Gran Canaria, Tenerife, La Gomera, La Palmera and El <span class="hlt">Hierro</span>. While the creation of the islands began in the Late Cretaceous Period (70 – 80 million years ago), active volcanic activity continues. In 2011, a spectacular submarine eruption occurred just off the shore of El <span class="hlt">Hierro</span>. The volcano became quiet again, but very recently increasing earthquakes and changing height of El <span class="hlt">Hierro</span> suggested the volcano may again be entering an active eruptive phase. On December 27 the island’s volcano monitoring agency had raised the volcanic eruption risk for El <span class="hlt">Hierro</span> to “yellow” – a code that means increasing activity but no eruption imminent. That afternoon a magnitude 5.1 earthquake struck offshore at El <span class="hlt">Hierro</span>. The epicenter was 9 miles (15 km) deep, and it was one of the largest quakes ever recorded at the island. Credit: NASA/GSFC/Jeff Schmaltz/MODIS Land Rapid Response Team NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2012EGUGA..14.5373A','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2012EGUGA..14.5373A"><span>The 2011 volcanic crisis at El <span class="hlt">Hierro</span> (Canary Islands): monitoring ground deformation through tiltmeter and gravimetric observations</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Arnoso, J.; Montesinos, F. G.; Benavent, M.; Vélez, E. J.</p> <p>2012-04-01</p> <p>El <span class="hlt">Hierro</span> is an ocean island located at the western end of the Canary Islands, and along with Tenerife and La Palma islands have been the most geologically active in the recent past. The island has a triple armed rift and, presently, is at the stage of growth, representing the summit of a volcanic shield elevating from the seafloor at depth of 4000 m up to 1501 m above the sea level (Münn et al., 2006; Carracedo et al., 1999). Since July 19th, 2011 seismic activity has produced more than 11950 events up to date. The seismic crisis resulted in a volcanic eruption that began on October 10th, being still currently active. The new volcano is located 2 km off the coast and about 300 m depth, in the submarine flank of the southern rift of the island, which is extended some 40 km length. Since September 2004 until November 2010 two continuous tilt stations were installed at the north, Balneario site (BA), and at the center of the island, Aula de la Naturaleza (AU) site. Both stations were used to assess the pattern of local ground movements in the island. When seismic swarm started on past July 2011, we have reinstalled both tilt stations (BA and AU) and 2 new ones located at the south of the island, namely Montaña Quemada (MQ) and Restinga (RE) sites. We have used short base platform tiltmeters that measure ground tilts with resolutions varying from 0.1 up to 0.01 microradians (µrad). On October 8th, a 4.4 magnitude earthquake took place and is supposed that fractured the ocean crust at some 8-10 km off the south coast of the island and about 1000 m depth. Typical spike signals were observed at the tilt stations. Two days after, the eruption onset was recorded also at tilt stations through a remarkable increase of the high frequency signal, being of large amplitude the components (radial) orientated towards the new volcano edifice. When compared with previous tiltmeter records in the island, tilt pattern were clearly modified several times at the stations when strong</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27378292','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27378292"><span><span class="hlt">Cons</span>Pred: a rule-based (re-)annotation framework for prokaryotic genomes.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Weinmaier, Thomas; Platzer, Alexander; Frank, Jeroen; Hellinger, Hans-Jörg; Tischler, Patrick; Rattei, Thomas</p> <p>2016-11-01</p> <p>The rapidly growing number of available prokaryotic genome sequences requires fully automated and high-quality software solutions for their initial and re-annotation. Here we present <span class="hlt">Cons</span>Pred, a prokaryotic genome annotation framework that performs intrinsic gene predictions, homology searches, predictions of non-coding genes as well as CRISPR repeats and integrates all evidence into a consensus annotation. <span class="hlt">Cons</span>Pred achieves comprehensive, high-quality annotations based on rules and priorities, similar to decision-making in manual curation and avoids conflicting predictions. Parameters controlling the annotation process are configurable by the user. <span class="hlt">Cons</span>Pred has been used in the institutions of the authors for longer than 5 years and can easily be extended and adapted to specific needs. The <span class="hlt">Cons</span>Pred algorithm for producing a consensus from the varying scores of multiple gene prediction programs approaches manual curation in accuracy. Its rule-based approach for choosing final predictions avoids overriding previous manual curations. <span class="hlt">Cons</span>Pred is implemented in Java, Perl and Shell and is freely available under the Creative Commons license as a stand-alone in-house pipeline or as an Amazon Machine Image for cloud computing, see https://sourceforge.net/projects/conspred/. thomas.rattei@univie.ac.atSupplementary information: Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://eric.ed.gov/?q=time+AND+travel+AND+real&id=EJ885998','ERIC'); return false;" href="https://eric.ed.gov/?q=time+AND+travel+AND+real&id=EJ885998"><span>Inter<span class="hlt">Con</span> Travel Health: Case B</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Truman, Gregory E.; Pachamanova, Dessislava A.; Goldstein, Michael A.</p> <p>2010-01-01</p> <p>Inter<span class="hlt">Con</span> provides services to health insurers of foreign tourists who travel to the United States and Canada. Management wants to implement a new information system that will deal with several operational problems, but it is having difficulty securing the capital resources to fund the system's development. After an initial failure, the chief…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26351131','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26351131"><span>Impact of the <span class="hlt">Con</span>Red program on different cyberbulling roles.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Del Rey, Rosario; Casas, José A; Ortega, Rosario</p> <p>2016-01-01</p> <p>This article presents results from an evaluation of the <span class="hlt">Con</span>Red cyberbullying intervention program. The program's impacts were separately determined for the different roles within cyberbullying that students can take, i.e., cyber-victims, cyber-bullies, cyber-bully/victims, and bystanders. The <span class="hlt">Con</span>Red program is a theory-driven program designed to prevent cyberbullying and improve cyberbullying coping skills. It involves students, teachers, and families. During a 3-month period, external experts conducted eight training sessions with students, two with teachers and one with families. <span class="hlt">Con</span>Red was evaluated through a quasi-experimental design, in which students from three secondary schools were separated into experimental and control groups. The sample comprised 875 students, aged between 11 and 19 years. More students (n = 586) were allocated to the experimental groups at the specific insistence of the management of all schools; the remainder (n = 289) formed the control. Repeated measures MANOVA showed that cyber victims, cyber aggressors and cyberbully/victims reduced their involvement in cyberbullying. Moreover, cyber-victims and bystanders adjusted their perceptions about their control of personal information on the Internet, and cyber aggressors and bystanders reduced their Internet dependence. The <span class="hlt">Con</span>Red program had stronger effects on male participants, especially in heightening their affective empathy. © 2015 Wiley Periodicals, Inc.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28693018','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28693018"><span>El efecto de la panfotocoagulación <span class="hlt">con</span> láser en edema macular diabético <span class="hlt">con</span> el fotocoagulador Pascal® versus el láser de argón convencional.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Mahgoub, Mohamed M; Macky, Tamer A</p> <p>2017-07-11</p> <p>Objetivo: El objetivo de este estudio fue comparar el efecto de la panfotocoagulación (PFC) en el edema macular diabético (EMD) en pacientes <span class="hlt">con</span> retinopatía diabética proliferativa (RDP) <span class="hlt">con</span> el fotocoagulador Pascal® (FP) vs. un fotocoagulador <span class="hlt">con</span> láser de argón convencional (FLAC). Métodos: Se aleatorizó el uso de FP o FLAC en ochenta ojos <span class="hlt">con</span> RDP y EMD <span class="hlt">con</span> afectación central de la mácula. Ambos grupos tuvieron una evaluación de base de mejor agudeza visual corregida y fueron examinados <span class="hlt">con</span> tomografía de coherencia óptica y angiografía <span class="hlt">con</span> fluoresceína. Resultados: El número medio de disparos de láser en los grupos de FP y FLAC fue 1.726,10 y 752,00 en la sesión 1 y 1.589,00 y 830,00 (p < 0,001) en la sesión 2, respectivamente. El grosor foveal central (GFC) medio antes de comenzar el estudio fue 306 ± 100 y 314 ± 98 en los grupos de FP y FLAC, respectivamente. A las 8 semanas, el GFC medio fue 332 ± 116 y 347 ± 111 en los grupos de FP y FLAC, respectivamente (p > 0,05). La MAVC media fue similar durante el periodo de estudio y no hubo ninguna diferencia significativa entre los grupos (p > 0,05). Conclusiones: El FP y el FLAC mostraron efectos similares en el EMD en ojos <span class="hlt">con</span> RDP y fueron igualmente seguros sin un aumento significativo del GFC. © 2017 S. Karger AG, Basel.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://cfpub.epa.gov/si/si_public_record_report.cfm?dirEntryId=220925&Lab=NERL&keyword=health+AND+physics&actType=&TIMSType=+&TIMSSubTypeID=&DEID=&epaNumber=&ntisID=&archiveStatus=Both&ombCat=Any&dateBeginCreated=&dateEndCreated=&dateBeginPublishedPresented=&dateEndPublishedPresented=&dateBeginUpdated=&dateEndUpdated=&dateBeginCompleted=&dateEndCompleted=&personID=&role=Any&journalID=&publisherID=&sortBy=revisionDate&count=50','EPA-EIMS'); return false;" href="https://cfpub.epa.gov/si/si_public_record_report.cfm?dirEntryId=220925&Lab=NERL&keyword=health+AND+physics&actType=&TIMSType=+&TIMSSubTypeID=&DEID=&epaNumber=&ntisID=&archiveStatus=Both&ombCat=Any&dateBeginCreated=&dateEndCreated=&dateBeginPublishedPresented=&dateEndPublishedPresented=&dateBeginUpdated=&dateEndUpdated=&dateBeginCompleted=&dateEndCompleted=&personID=&role=Any&journalID=&publisherID=&sortBy=revisionDate&count=50"><span>Meeting Report: Breath Biomarkers Networking Sessions at Pitt<span class="hlt">Con</span> 2010, Orlando, Florida</span></a></p> <p><a target="_blank" href="http://oaspub.epa.gov/eims/query.page">EPA Science Inventory</a></p> <p></p> <p></p> <p>The Pittsburgh Conference and Exposition, or "Pitt<span class="hlt">Con</span>" (www.pittcon.org/), is one of the largest international conferences for analytical chemistry and instrumentation typically attracting about 25,000 attendees and 1,000 commercial exhibitors. Pitt<span class="hlt">Con</span> began in 1950 as a small sp...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014SPIE.8951E..0AC','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014SPIE.8951E..0AC"><span><span class="hlt">Con</span>A-based glucose sensing using the long-lifetime azadioxatriangulenium fluorophore</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Cummins, Brian; Simpson, Jonathan; Gryczynski, Zygmunt; Sørensen, Thomas Just; Laursen, Bo W.; Graham, Duncan; Birch, David; Coté, Gerard</p> <p>2014-02-01</p> <p>Fluorescent glucose sensing technologies have been identified as possible alternatives to current continuous glucose monitoring approaches. We have recently introduced a new, smart fluorescent ligand to overcome the traditional problems of <span class="hlt">Con</span>A-based glucose sensors. For this assay to be translated into a continuous glucose monitoring device where both components are free in solution, the molecular weight of the smart fluorescent ligand must be increased. We have identified ovalbumin as a naturally-occurring glycoprotein that could serve as the core-component of a 2nd generation smart fluorescent ligand. It has a single asparagine residue that is capable of displaying an N-linked glycan and a similar isoelectric point to <span class="hlt">Con</span>A. Thus, binding between <span class="hlt">Con</span>A and ovalbumin can potentially be monovalent and sugar specific. This work is the preliminary implementation of fluorescently-labeled ovalbumin in the <span class="hlt">Con</span>A-based assay. We conjugate the red-emitting, long-lifetime azadioxatriangulenium (ADOTA+) dye to ovalbumin, as ADOTA have many advantageous properties to track the equilibrium binding of the assay. The ADOTA-labeled ovalbumin is paired with Alexa Fluor 647-labeled <span class="hlt">Con</span>A to create a Förster Resonance Energy Transfer (FRET) assay that is glucose dependent. The assay responds across the physiologically relevant glucose range (0-500 mg/dL) with increasing intensity from the ADOTA-ovalbumin, showing that the strategy may allow for the translation of the smart fluorescent ligand concept into a continuous glucose monitoring device.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26356902','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26356902"><span><span class="hlt">Con</span>Tour: Data-Driven Exploration of Multi-Relational Datasets for Drug Discovery.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Partl, Christian; Lex, Alexander; Streit, Marc; Strobelt, Hendrik; Wassermann, Anne-Mai; Pfister, Hanspeter; Schmalstieg, Dieter</p> <p>2014-12-01</p> <p>Large scale data analysis is nowadays a crucial part of drug discovery. Biologists and chemists need to quickly explore and evaluate potentially effective yet safe compounds based on many datasets that are in relationship with each other. However, there is a lack of tools that support them in these processes. To remedy this, we developed <span class="hlt">Con</span>Tour, an interactive visual analytics technique that enables the exploration of these complex, multi-relational datasets. At its core <span class="hlt">Con</span>Tour lists all items of each dataset in a column. Relationships between the columns are revealed through interaction: selecting one or multiple items in one column highlights and re-sorts the items in other columns. Filters based on relationships enable drilling down into the large data space. To identify interesting items in the first place, <span class="hlt">Con</span>Tour employs advanced sorting strategies, including strategies based on connectivity strength and uniqueness, as well as sorting based on item attributes. <span class="hlt">Con</span>Tour also introduces interactive nesting of columns, a powerful method to show the related items of a child column for each item in the parent column. Within the columns, <span class="hlt">Con</span>Tour shows rich attribute data about the items as well as information about the connection strengths to other datasets. Finally, <span class="hlt">Con</span>Tour provides a number of detail views, which can show items from multiple datasets and their associated data at the same time. We demonstrate the utility of our system in case studies conducted with a team of chemical biologists, who investigate the effects of chemical compounds on cells and need to understand the underlying mechanisms.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/servlets/purl/960293','SCIGOV-STC'); return false;" href="https://www.osti.gov/servlets/purl/960293"><span>SLUDGE PARTICLE SEPAPATION EFFICIENCIES DURING SETTLER TANK RETRIEVAL INTO SCS-<span class="hlt">CON</span>-230</span></a></p> <p><a target="_blank" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a></p> <p>DEARING JI; EPSTEIN M; PLYS MG</p> <p>2009-07-16</p> <p>The purpose of this document is to release, into the Hanford Document Control System, FA1/0991, Sludge Particle Separation Efficiencies for the Rectangular SCS-<span class="hlt">CON</span>-230 Container, by M. Epstein and M. G. Plys, Fauske & Associates, LLC, June 2009. The Sludge Treatment Project (STP) will retrieve sludge from the 105-K West Integrated Water Treatment System (IWTS) Settler Tanks and transfer it to container SCS-<span class="hlt">CON</span>-230 using the Settler Tank Retrieval System (STRS). The sludge will enter the container through two distributors. The container will have a filtration system that is designed to minimize the overflow of sludge fines from the container to themore » basin. FAI/09-91 was performed to quantify the effect of the STRS on sludge distribution inside of and overflow out of SCS-<span class="hlt">CON</span>-230. Selected results of the analysis and a system description are discussed. The principal result of the analysis is that the STRS filtration system reduces the overflow of sludge from SCS-<span class="hlt">CON</span>-230 to the basin by roughly a factor of 10. Some turbidity can be expected in the center bay where the container is located. The exact amount of overflow and subsequent turbidity is dependent on the density of the sludge (which will vary with location in the Settler Tanks) and the thermal gradient between the SCS-<span class="hlt">CON</span>-230 and the basin. Attachment A presents the full analytical results. These results are applicable specifically to SCS-<span class="hlt">CON</span>-230 and the STRS filtration system's expected operating duty cycles.« less</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4080002','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4080002"><span>Virulence, Speciation and Antibiotic Susceptibility of Ocular Coagualase Negative Staphylococci (<span class="hlt">CoNS</span>)</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Priya, Ravindran; Mythili, Arumugam; Singh, Yendremban Randhir Babu; Sreekumar, Haridas; Manikandan, Palanisamy; Panneerselvam, Kanesan</p> <p>2014-01-01</p> <p>Background: Coagulase negative Staphylococci (<span class="hlt">CoNS</span>) are common inhabitants of human skin and mucous membranes. With the emergence of these organisms as prominent pathogens in patients with ocular infections, investigation has intensified in an effort to identify important virulence factors and to inform new approaches to treatment and prevention. Aim: To isolate <span class="hlt">CoNS</span> from ocular specimens; to study the possible virulence factors; speciation of coagulase negative staphylococci (<span class="hlt">CoNS</span>) which were isolated from ocular complications; antibiotic susceptibility testing of ocular <span class="hlt">CoNS</span>. Materials and Methods: The specimens were collected from the target patients who attended the Microbiology Laboratory of a tertiary care eye hospital in Coimbatore, Tamilnadu state, India. The isolates were subjected to tube and slide coagulase tests for the identification of <span class="hlt">CoNS</span>. All the isolates were subjected to screening for lipase and protease activities. Screening for other virulence factors viz., slime production on Congo red agar medium and haemagglutination assay with use of 96-well microtitre plates. These isolates were identified upto species level by performing biochemical tests such as phosphatase test, arginine test, maltose and trehalose fermentation tests and novobiocin sensitivity test. The isolates were subjected to antibiotic susceptibility studies, based on the revised standards of Clinical and Laboratory Standards Institutes (CLSI). Results: During the one year of study, among the total 260 individuals who were screened, 100 isolates of <span class="hlt">CoNS</span> were obtained. Lipolytic activity was seen in all the isolates, whereas 38 isolates showed a positive result for protease. A total of 63 isolates showed slime production. Of 100 isolates, 30 isolates were analyzed for haemagglutination, where 4 isolates showed the capacity to agglutinate the erythrocytes. The results of the biochemical analysis revealed that of the 100 isolates of <span class="hlt">CoNS</span>, 43% were Staphylococcus epidermidis. The other</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_6");'>6</a></li> <li><a href="#" onclick='return showDiv("page_7");'>7</a></li> <li class="active"><span>8</span></li> <li><a href="#" onclick='return showDiv("page_9");'>9</a></li> <li><a href="#" onclick='return showDiv("page_10");'>10</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_8 --> <div id="page_9" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_7");'>7</a></li> <li><a href="#" onclick='return showDiv("page_8");'>8</a></li> <li class="active"><span>9</span></li> <li><a href="#" onclick='return showDiv("page_10");'>10</a></li> <li><a href="#" onclick='return showDiv("page_11");'>11</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="161"> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014EGUGA..1615418M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014EGUGA..1615418M"><span>A new approach to the unrest and subsequent eruption at El <span class="hlt">Hierro</span> Island (2011) based on petrological, seismological, geodetical and gravimetric data</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Meletlidis, Stavros; Di Roberto, Alessio; Domínguez Cerdeña, Itahiza; Pompilio, Massimo; García-Cañada, Laura; Bertagnini, Antonella; Benito Saz, Maria Angeles; Del Carlo, Paola; Sainz-Maza Aparicio, Sergio; Lopez Moreno, Carmen; Moure García, David</p> <p>2014-05-01</p> <p>A shallow submarine eruption took place on 10th October 2011, about 1.8 km off the coast of La Restinga, a small village located in El <span class="hlt">Hierro</span> (Canary Islands, Spain). The eruption lasted for about four months and ended by early March 2012. The eruption was preceded by an unrest episode that initiated about three months before, in July 2011, and characterized by more than 10,000 localized earthquakes accompanied by up to 5 cm of vertical ground deformation. In the Canary Islands, this event represents the first case of an eruption that was monitored since the unrest to the end by the monitoring network of IGN (Instituto Geográfico National), providing a huge dataset that includes geophysical (seismic, magnetic and gravimetric), geodetic, geochemistry and petrological data. In this work we use the seismic, GPS and gravity records collected by IGN along with the petrological data derived from the study of various lava balloons, scoriaceous fragments and ash.Geophysical and geochemical monitoring tools provide a variety of information that need to be interpreted in terms of magma movement and/or interaction of magma with host rocks. We present a model, based on this data, which describes the intrusion and ascent of the magma. According to this model, a major intrusion beneath and around preexisting high-density magmatic bodies, localized in the central sector of the island, led to an eruption in the Southern sector of the island. After a failed attempt to reach the surface, while various dykes were emplaced, through a low fractured area in the Central and Northern parts of the island, the ascending magma finally found its way in the submarine area of La Restinga, in the South rift zone, at a depth of 350 m below sea level. Feeding of the eruption was achieved by the ascension of an important volume of material from the upper mantle which was emplaced near the crust-mantle boundary. However, the very energetic post-eruptive unrests - we had five episodes up today with</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2759973','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2759973"><span>Enrichment of Glycoproteins using Nano-scale Chelating <span class="hlt">Con</span> A Monolithic Capillary Chromatography</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Feng, Shun; Yang, Na; Pennathur, Subramaniam; Goodison, Steve; Lubman, David M.</p> <p>2009-01-01</p> <p>Immobilized lectin chromatography can be employed for glycoprotein enrichment, but commonly used columns have limitations of yield and resolution. In order to improve efficiency and to make the technique applicable to minimal sample material, we have developed a nano-scale chelating Concanavalin A (<span class="hlt">Con</span> A) monolithic capillary prepared using GMA-EDMA (glycidyl methacrylate–co-ethylene dimethacrylate) as polymeric support. <span class="hlt">Con</span> A was immobilized on Cu(II)-charged iminodiacetic acid (IDA) regenerable sorbents by forming a IDA:Cu(II):<span class="hlt">Con</span> A sandwich affinity structure that has high column capacity as well as stability. When compared with conventional <span class="hlt">Con</span> A lectin chromatography, the monolithic capillary enabled the better reproducible detection of over double the number of unique N-glycoproteins in human urine samples. Utility for analysis of minimal biological samples was confirmed by the successful elucidation of glycoprotein profiles in mouse urine samples at the microliter scale. The improved efficiency of the nano-scale monolithic capillary will impact the analysis of glycoproteins in complex biological samples, especially where only limited material may be available. PMID:19366252</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/CFR-2011-title9-vol2/pdf/CFR-2011-title9-vol2-sec319-300.pdf','CFR2011'); return false;" href="https://www.gpo.gov/fdsys/pkg/CFR-2011-title9-vol2/pdf/CFR-2011-title9-vol2-sec319-300.pdf"><span>9 CFR 319.300 - Chili <span class="hlt">con</span> carne.</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collectionCfr.action?selectedYearFrom=2011&page.go=Go">Code of Federal Regulations, 2011 CFR</a></p> <p></p> <p>2011-01-01</p> <p>... CERTIFICATION DEFINITIONS AND STANDARDS OF IDENTITY OR COMPOSITION Canned, Frozen, or Dehydrated Meat Food... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Chili <span class="hlt">con</span> carne. 319.300 Section 319.300 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/CFR-2010-title9-vol2/pdf/CFR-2010-title9-vol2-sec319-300.pdf','CFR'); return false;" href="https://www.gpo.gov/fdsys/pkg/CFR-2010-title9-vol2/pdf/CFR-2010-title9-vol2-sec319-300.pdf"><span>9 CFR 319.300 - Chili <span class="hlt">con</span> carne.</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collectionCfr.action?selectedYearFrom=2010&page.go=Go">Code of Federal Regulations, 2010 CFR</a></p> <p></p> <p>2010-01-01</p> <p>... CERTIFICATION DEFINITIONS AND STANDARDS OF IDENTITY OR COMPOSITION Canned, Frozen, or Dehydrated Meat Food... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Chili <span class="hlt">con</span> carne. 319.300 Section 319.300 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4361383','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4361383"><span>Optimizing Electrospray Interfaces Using Slowly Diverging Conical Duct (<span class="hlt">Con</span>Duct) Electrodes</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Krutchinsky, Andrew N.; Padovan, Júlio C.; Cohen, Herbert; Chait, Brian T.</p> <p>2015-01-01</p> <p>We demonstrate that the efficiency of ion transmission from atmosphere to vacuum through stainless steel electrodes that contain slowly divergent conical duct (<span class="hlt">Con</span>Duct) channels can be close to 100%. Here, we explore the properties of 2.5 cm long electrodes with angles of divergence of 0°, 1°, 2°, 3°, 5°, 8°, 13°, and 21°, respectively. The ion transmission efficiency was observed to jump from 10–20% for the 0° (straight) channels to 90–95% for channels with an angle of divergence as small as 1°. Furthermore, the 2–3° <span class="hlt">Con</span>Duct electrodes produced extraordinarily low divergence ion beams that propagated in a laser-like fashion over long distances in vacuum. To take advantage of these newly discovered properties, we constructed a novel atmosphere-to-vacuum ion interface utilizing a 2° <span class="hlt">Con</span>Duct as an inlet electrode and compared its ion transmission efficiency with that of the interface used in the commercial (Thermo) Velos Orbitrap and Q Exactive mass spectrometers. We observed that the <span class="hlt">Con</span>Duct interface transmitted up to 17 times more ions than the commercial reference interface and also yielded improved signal-to-noise mass spectra of peptides. We infer from these results that the performance of many current atmosphere-tovacuum interfaces utilizing metal capillaries can be substantially improved by replacing them with 1° or 2° metal <span class="hlt">Con</span>Duct electrodes, which should preserve the convenience of supplying ion desolvation energy by heating the electrode while greatly increasing the efficiency of ion transmission into the mass spectrometer. PMID:25667060</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015JASMS..26..659K','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015JASMS..26..659K"><span>Optimizing Electrospray Interfaces Using Slowly Diverging Conical Duct (<span class="hlt">Con</span>Duct) Electrodes</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Krutchinsky, Andrew N.; Padovan, Júlio C.; Cohen, Herbert; Chait, Brian T.</p> <p>2015-04-01</p> <p>We demonstrate that the efficiency of ion transmission from atmosphere to vacuum through stainless steel electrodes that contain slowly divergent conical duct (<span class="hlt">Con</span>Duct) channels can be close to 100%. Here, we explore the properties of 2.5-cm-long electrodes with angles of divergence of 0°, 1°, 2°, 3°, 5°, 8°, 13°, and 21°, respectively. The ion transmission efficiency was observed to jump from 10-20% for the 0° (straight) channels to 90-95% for channels with an angle of divergence as small as 1°. Furthermore, the 2-3° <span class="hlt">Con</span>Duct electrodes produced extraordinarily low divergence ion beams that propagated in a laser-like fashion over long distances in vacuum. To take advantage of these newly discovered properties, we constructed a novel atmosphere-to-vacuum ion interface utilizing a 2° <span class="hlt">Con</span>Duct as an inlet electrode and compared its ion transmission efficiency with that of the interface used in the commercial (Thermo Fisher Scientific, San Jose, CA, USA) Velos Orbitrap and Q Exactive mass spectrometers. We observed that the <span class="hlt">Con</span>Duct interface transmitted up to 17 times more ions than the commercial reference interface and also yielded improved signal-to-noise mass spectra of peptides. We infer from these results that the performance of many current atmosphere-to-vacuum interfaces utilizing metal capillaries can be substantially improved by replacing them with 1° or 2° metal <span class="hlt">Con</span>Duct electrodes, which should preserve the convenience of supplying ion desolvation energy by heating the electrode while greatly increasing the efficiency of ion transmission into the mass spectrometer.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29683151','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29683151"><span>Sele<span class="hlt">Con</span>: Scalable IoT Device Selection and Control Using Hand Gestures.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Alanwar, Amr; Alzantot, Moustafa; Ho, Bo-Jhang; Martin, Paul; Srivastava, Mani</p> <p>2017-04-01</p> <p>Although different interaction modalities have been proposed in the field of human-computer interface (HCI), only a few of these techniques could reach the end users because of scalability and usability issues. Given the popularity and the growing number of IoT devices, selecting one out of many devices becomes a hurdle in a typical smarthome environment. Therefore, an easy-to-learn, scalable, and non-intrusive interaction modality has to be explored. In this paper, we propose a pointing approach to interact with devices, as pointing is arguably a natural way for device selection. We introduce Sele<span class="hlt">Con</span> for device selection and control which uses an ultra-wideband (UWB) equipped smartwatch. To interact with a device in our system, people can point to the device to select it then draw a hand gesture in the air to specify a control action. To this end, Sele<span class="hlt">Con</span> employs inertial sensors for pointing gesture detection and a UWB transceiver for identifying the selected device from ranging measurements. Furthermore, Sele<span class="hlt">Con</span> supports an alphabet of gestures that can be used for controlling the selected devices. We performed our experiment in a 9 m -by-10 m lab space with eight deployed devices. The results demonstrate that Sele<span class="hlt">Con</span> can achieve 84.5% accuracy for device selection and 97% accuracy for hand gesture recognition. We also show that Sele<span class="hlt">Con</span> is power efficient to sustain daily use by turning off the UWB transceiver, when a user's wrist is stationary.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28693020','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28693020"><span>Propiedades biomecánicas de la membrana limitante interna tras recibir tratamiento intravítreo <span class="hlt">con</span> ocriplasmina.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Vielmuth, Franziska; Schumann, Ricarda G; Spindler, Volker; Wolf, Armin; Scheler, Renate; Mayer, Wolfgang J; Henrich, Paul B; Haritoglou, Christos</p> <p>2017-01-01</p> <p>Objetivo: Evaluar la rigidez de la membrana limitante interna (MLI) humana y evaluar los posibles cambios de las propiedades mecánicas tras administrar una inyección intravítrea de ocriplasmina para tratar la tracción vitreomacular. Métodos: Este estudio se compone de una serie de casos intervencionales y comparativos de 12 muestras de MLI extraídas mediante cirugía y obtenidas de forma consecutiva de 9 ojos de 9 pacientes después de someterse sin éxito a vitreólisis farmacológica <span class="hlt">con</span> ocriplasmina. Durante el mismo periodo de tiempo, 16 muestras de otros 13 ojos sin tratamiento <span class="hlt">con</span> ocriplasmina se obtuvieron mediante vitrectomía y sirvieron como controles. Todos los pacientes presentaron agujeros maculares o tracción vitreomacular y se sometieron a vitrectomía <span class="hlt">con</span> disección de la MLI tanto <span class="hlt">con</span> tinción <span class="hlt">con</span> azul brillante (AB) como sin ella. Todas las muestras se analizaron <span class="hlt">con</span> un microscopio de fuerza atómica <span class="hlt">con</span> imágenes de las regiones de 25 × 25 μm. En todas las muestras, se analizaron tanto la parte de la retina como la del vítreo de la MLI. Resultados: La microscopia de fuerza atómica no reveló diferencias significativas en cuanto a elasticidad de las muestras de MLI extraídas de ojos <span class="hlt">con</span> o sin tratamiento <span class="hlt">con</span> ocriplasmina. Las áreas onduladas de la parte de la retina presentaron una mayor rigidez que la parte del vítreo de la MLI. La cartografía topográfica tanto de la parte del vítreo como de la retina de la MLI no mostró ninguna alteración aparente de la morfología en ojos tratados <span class="hlt">con</span> ocriplasmina en comparación <span class="hlt">con</span> los ojos no tratados. La tinción <span class="hlt">con</span> azul brillante conllevó un aumento de la rigidez tisular. Conclusiones: Las inyecciones intravítreas de ocriplasmina no varían las propiedades biomecánicas de la MLI humana. No existen pruebas de un posible efecto enzimático que interfiera <span class="hlt">con</span> la rigidez de esta membrana basal. © 2017 S. Karger AG, Basel.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/3129359','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/3129359"><span>B cells as accessory cells in a <span class="hlt">Con</span> A response of a T cell clone.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Takeuchi, M; Kakiuchi, T; Taira, S; Nariuchi, H</p> <p>1987-12-01</p> <p>Accessory cell (AC) function of B cells was examined in <span class="hlt">Con</span> A response of a cloned T cell line, 22-9D, which is Thy 1+,L3T4+,Lyt2-,H-2KbDb+ and I-Ab-.22-9D cells produced IL 2 in the presence of <span class="hlt">Con</span> A without participation of AC. For the initiation of a proliferative response to <span class="hlt">Con</span> A, the addition of spleen cells or spleen adherent cells was required. B cells as AC were unable to induce the proliferative response. In the presence of culture supernatant of spleen cells stimulated with <span class="hlt">Con</span> A (CAS), 22-9D cells showed proliferative response to <span class="hlt">Con</span> A with B cell AC. The response was inhibited by a relevant monoclonal anti-I-A antibody. Although irradiated spleen cells as AC induced IL 2 receptor expression of 22-9D cells in the presence of <span class="hlt">Con</span> A, B cells were shown to require the addition of unknown factor(s) in CAS, which was suggested to be different from IL 1, IL 2, IL 3, or IFN-gamma, for the induction of the receptor expression on 22-9D cells.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/servlets/purl/1304738','SCIGOV-STC'); return false;" href="https://www.osti.gov/servlets/purl/1304738"><span>Wildland Fire Induced Heating of Dome 375 Perma-<span class="hlt">Con</span>®</span></a></p> <p><a target="_blank" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a></p> <p>Flores, Eugene Michael</p> <p></p> <p>AET-1 was tasked by ADEM with determining the temperature rise in the drum contents of drums stored in the Dome 375 Perma-<span class="hlt">Con</span>® at TA-54 given a wildland fire. The wildland fire causes radiative and convective heating on the Perma-<span class="hlt">Con</span>® exterior. The wildland fire time histories for the radiative and convective heating environment were provided to AET-1 by EES-16. If the calculated temperature rise results in a drum content temperature over 40 °C, then ADEM desires a design solution to ensure the peak temperature remains below 40 °C. An axi-symmetric FE simulation was completed to determine the peak temperature of themore » contents of a drum stored in the Dome 375 Perma-<span class="hlt">Con</span>® during a wildland fire event. Three wildland fire time histories for the radiative and convective heat transfer were provided by EES-16 and were inputs for the FE simulation. The maximum drum content temperature reached was found to be 110 °C while using inputs from the SiteG_2ms_4ign_wind_from_west.xlsx time history input and not including the SWB in the model. Including the SWB in the results in a peak drum content temperature of 61 °C for the SiteG_2ms_4ign_wind_from_west.xlsx inputs. EES-16 decided that by using fuel mitigation efforts, such as mowing the grass and shrubs near the Perma-<span class="hlt">Con</span>® they could reduce the shrub/grass fuel loading near the Perma-<span class="hlt">Con</span>® from 1.46 kg/m 2 to 0.146 kg/m 2 and by using a less conservative fuel loading for the debris field inside the Dome 375 perimeter, reducing it from 0.58 kg/m2 to 0.058 kg/m 2 in their model. They also greatly increased the resolution of their radiation model and increased the accuracy of their model’s required convergence value. Using this refined input the maximum drum content temperature was found to be 28 °C with no SWB present in the model. Additionally, this refined input model was modified to include worst case emissivity values for the concrete, drum and Perma-<span class="hlt">Con</span>® interior, along with adding a 91 second long</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3884680','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3884680"><span>La salud en personas <span class="hlt">con</span> discapacidad intelectual en España: estudio europeo POMONA-II</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Martínez-Leal, Rafael; Salvador-Carulla, Luis; Gutiérrez-Colosía, Mencía Ruiz; Nadal, Margarida; Novell-Alsina, Ramón; Martorell, Almudena; González-Gordón, Rodrigo G.; Mérida-Gutiérrez, M. Reyes; Ángel, Silvia; Milagrosa-Tejonero, Luisa; Rodríguez, Alicia; García-Gutiérrez, Juan C.; Pérez-Vicente, Amado; García-Ibáñez, José; Aguilera-Inés, Francisco</p> <p>2011-01-01</p> <p>Introducción Estudios internacionales demuestran que existe un patrón diferenciado de salud y una disparidad en la atención sanitaria entre personas <span class="hlt">con</span> discapacidad intelectual (DI) y población general. Objetivo Obtener datos sobre el estado de salud de las personas <span class="hlt">con</span> DI y compararlos <span class="hlt">con</span> datos de población general. Pacientes y métodos Se utilizó el conjunto de indicadores de salud P15 en una muestra de 111 sujetos <span class="hlt">con</span> DI. Los datos de salud encontrados se compararon según el tipo de residencia de los sujetos y se utilizó la Encuesta Nacional de Salud 2006 para comparar estos datos <span class="hlt">con</span> los de la población general. Resultados La muestra <span class="hlt">con</span> DI presentó 25 veces más casos de epilepsia y el doble de obesidad. Un 20% presentó dolor bucal, y existió una alta presencia de problemas sensoriales, de movilidad y psicosis. Sin embargo, encontramos una baja presencia de patologías como la diabetes, la hipertensión, la osteoartritis y la osteoporosis. También presentaron una menor participación en programas de prevención y promoción de la salud, un mayor número de ingresos hospitalarios y un uso menor de los servicios de urgencia. Conclusiones El patrón de salud de las personas <span class="hlt">con</span> DI difiere del de la población general, y éstas realizan un uso distinto de los servicios sanitarios. Es importante el desarrollo de programas de promoción de salud y de formación profesional específicamente diseñados para la atención de personas <span class="hlt">con</span> DI, así como la implementación de encuestas de salud que incluyan datos sobre esta población. PMID:21948011</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/biblio/81793-energy-star-program-benefits-con-edison','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/81793-energy-star-program-benefits-con-edison"><span>Energy Star program benefits <span class="hlt">Con</span> Edison</span></a></p> <p><a target="_blank" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a></p> <p>NONE</p> <p></p> <p>Impressed with savings in energy costs achieved after upgrading the lighting and air conditioning systems at its Manhattan headquarters, Home Box Office (HBO) wanted to do more, James Flock, vice president for computer and office systems, contacted <span class="hlt">Con</span> Edison Co. of New York in March 1991 to determine what the company could do to save money by reducing energy consumed by personal computers. Arthur Kressner, <span class="hlt">Con</span> Edison Research and Development manager contacted industry organizations and manufacturers for advice, but was told only to shut off computers at night and on weekends. Kressner arranged a series of meetings with IBM andmore » the Electric Power Research Institute (EPRI) to discuss the issue, then approached the U.S. Environmental Protection Agency (EPA), which was designing a program to promote the introduction and use of energy-efficient office equipment. In 1992, the EPA announced the Energy Star program for PCs, enabling manufacturers to display the Energy Star logo on machines meeting program criteria, including the ability to enter a sleep mode in which neither the computer nor monitor consume more than 30 W or electricity. Industry experts estimate national energy consumption by office equipment could double by the year 2000, but Energy Star equipment is expected to improve efficiency and help maintain electric loads.« less</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5909733','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5909733"><span>Sele<span class="hlt">Con</span>: Scalable IoT Device Selection and Control Using Hand Gestures</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Alanwar, Amr; Alzantot, Moustafa; Ho, Bo-Jhang; Martin, Paul; Srivastava, Mani</p> <p>2018-01-01</p> <p>Although different interaction modalities have been proposed in the field of human-computer interface (HCI), only a few of these techniques could reach the end users because of scalability and usability issues. Given the popularity and the growing number of IoT devices, selecting one out of many devices becomes a hurdle in a typical smarthome environment. Therefore, an easy-to-learn, scalable, and non-intrusive interaction modality has to be explored. In this paper, we propose a pointing approach to interact with devices, as pointing is arguably a natural way for device selection. We introduce Sele<span class="hlt">Con</span> for device selection and control which uses an ultra-wideband (UWB) equipped smartwatch. To interact with a device in our system, people can point to the device to select it then draw a hand gesture in the air to specify a control action. To this end, Sele<span class="hlt">Con</span> employs inertial sensors for pointing gesture detection and a UWB transceiver for identifying the selected device from ranging measurements. Furthermore, Sele<span class="hlt">Con</span> supports an alphabet of gestures that can be used for controlling the selected devices. We performed our experiment in a 9m-by-10m lab space with eight deployed devices. The results demonstrate that Sele<span class="hlt">Con</span> can achieve 84.5% accuracy for device selection and 97% accuracy for hand gesture recognition. We also show that Sele<span class="hlt">Con</span> is power efficient to sustain daily use by turning off the UWB transceiver, when a user’s wrist is stationary. PMID:29683151</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28430553','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28430553"><span>Sport Concussion Management Using Facebook: A Feasibility Study of an Innovative Adjunct "i<span class="hlt">Con</span>".</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Ahmed, Osman Hassan; Schneiders, Anthony G; McCrory, Paul R; Sullivan, S John</p> <p>2017-04-01</p> <p>  Sport concussion is currently the focus of much international attention. Innovative methods to assist athletic trainers in facilitating management after this injury need to be investigated.   To investigate the feasibility of using a Facebook concussion-management program termed i<span class="hlt">Con</span> (interactive concussion management) to facilitate the safe return to play (RTP) of young persons after sport concussion.   Observational study.   Facebook group containing interactive elements, with moderation and support from trained health care professionals.   Eleven participants (n = 9 men, n = 2 women; range, 18 to 28 years old) completed the study.   The study was conducted over a 3-month period, with participant questionnaires administered preintervention and postintervention. The primary focus was on the qualitative experiences of the participants and the effect of i<span class="hlt">Con</span> on their RTP. Usage data were also collected.   At the completion of the study, all participants (100%) stated that they would recommend an intervention such as i<span class="hlt">Con</span> to others. Their supporting quotes all indicated that i<span class="hlt">Con</span> has the potential to improve the management of concussion among this cohort. Most participants (n = 9, 82%) stated they were better informed with regard to their RTP due to participating in i<span class="hlt">Con</span>.   This interactive adjunct to traditional concussion management was appreciated among this participant group, which indicates the feasibility of a future, larger study of i<span class="hlt">Con</span>. Athletic trainers should consider the role that multimedia technologies may play in assisting with the management of sport concussion.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22542630','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22542630"><span>Influence of protic ionic liquids on the structure and stability of succinylated <span class="hlt">Con</span> A.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Attri, Pankaj; Venkatesu, Pannuru</p> <p>2012-01-01</p> <p>We report the synthesis of a series of ionic liquids (ILs) from various ions having different kosmotropicity including dihydrogen phosphate (H(2)PO(4)(-)), hydrogen sulfate (HSO(4)(-)) and acetate (CH(3)COO(-)) as anions and chaotropic cation such as trialkylammonium cation. To characterize the biomolecular interactions of ILs with protein, we have explored the stability of succinylated <span class="hlt">Con</span> A (S <span class="hlt">Con</span> A) in the presence of these aqueous ILs, which are varied combinations of kosmotropic anion with chaotropic cation such as triethylammonium dihydrogen phosphate [(CH(3)CH(2))(3)NH][H(2)PO(4)] (TEAP), trimethylammonium acetate [(CH(3))(3)NH][CH(3)COO] (TMAA), trimethylammonium dihydrogen phosphate [(CH(3))(3)NH][H(2)PO(4)] (TMAP) and trimethylammonium hydrogen sulfate [(CH(3))(3)NH][HSO(4)] (TMAS). Circular dichroism (CD) and fluorescence experiments have been used to characterize the stability of S <span class="hlt">Con</span> A by ILs. Our data distinctly demonstrate that the long alkyl chain IL TEAP is a strong stabilizer for S <span class="hlt">Con</span> A. Further, our experimental results reveal that TEAP is an effective refolding enhancer for S <span class="hlt">Con</span> A from a thermally denatured protein structure. Copyright © 2012 Elsevier B.V. All rights reserved.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2013AGUSM.G33A..06R','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2013AGUSM.G33A..06R"><span>Apoyo a Estudios Geodinamicos <span class="hlt">con</span> GPS en Guatemala</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Robles, V. R.</p> <p>2013-05-01</p> <p>El Instituto Geografico Nacional de Guatemala implemento 17 estaciones GNSS en el año 2009, como un proyecto de credito mixto de donacion de equipamiento del Gobierno de Suiza, el cual, este equipamiento de estaciones CORS GNSS es un sistema de recepción y transmisión de datos crudos GPS RInex que utiliza la tecnologia Spider Web de Leica, asi mismo este sistema esta sirviendo para el espablecimiento de un marco geodesico nacional de coordenadas geodesicas oficiales, el cual se calculan u obtienen las velocidades en tiempos temporales programados de las 17 Estaciones CORS. La infraestructura del marco geodesico de Guatemala esta sirviendo de base para las aplicaciones de estudios geodinamicos como el monitoreo de del desplazamiento de las placas tectonicas por medio de un estudio que se inicio en el año de 1999, llamado medicion <span class="hlt">con</span> GPS el sistema de Fallas de los rios Polochic Motagua de Guatemala, tambien para un estudio que se implemento para deformación de corteza terrestre local en un Volcan Activo de Guatemala llamado Pacaya. Para el estudio de medicion <span class="hlt">con</span> GPS en el sistema de falla de los Rios del polochic Motagua se implementaron 16 puntos para medir <span class="hlt">con</span> GPS de dos frecuencias en el año de 1999, el cual, tres puntos son estaciones geodesicas CORS IGS llamados GUAT, ELEN y HUEH, despues en el año de 2003 se hizo otra medicion en un total de 20 puntos, que permitió calcular las velocidades de desplazamieinto de los puntos en mención, usando como referencia el modelo NUVEL 1A de DeMets de la placa de Norteamerica. Este estudio fue en cooperación internacional por la universidad de Nice de Francia y el IGNde Francia. Para el estudio del monitoreo <span class="hlt">con</span> GPS del volcan activo de Guatemala, se implementaron cuatro puntos al rededor del volcan, el cual, se realizan cuatro mediciones al año, que permiten determinar axialmente la distancias entre los puntos, y rebisar estadisticamente cual es el comportamiento de las distancias en funcion del tiempo, si</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29386968','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29386968"><span>A Review of Staphylococcal Cassette Chromosome mec (SCCmec) Types in Coagulase-Negative Staphylococci (<span class="hlt">CoNS</span>) Species.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Saber, Huda; Jasni, Azmiza Syawani; Jamaluddin, Tengku Zetty Maztura Tengku; Ibrahim, Rosni</p> <p>2017-10-01</p> <p>Coagulase-negative staphylococci (<span class="hlt">CoNS</span>) are considered low pathogenic organisms. However, they are progressively causing more serious infections with time because they have adapted well to various antibiotics owing to their ability to form biofilms. Few studies have been conducted on <span class="hlt">CoNS</span> in both, hospital and community-acquired settings, especially in Malaysia. Thus, it is important to study their species and gene distributions. A mobile genetic element, staphylococcal cassette chromosome mec (SCC mec ), plays an important role in staphylococci pathogenesis. Among <span class="hlt">CoNS</span>, SCC mec has been studied less frequently than Staphylococcus aureus (coagulase-positive staphylococci). A recent study (8) conducted in Malaysia successfully detected SCC mec type I to VIII as well as several new combination patterns in <span class="hlt">CoNS</span> species, particularly Staphylococcus epidermidis . However, data are still limited, and further research is warranted. This paper provides a review on SCC mec types among <span class="hlt">CoNS</span> species.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://rosap.ntl.bts.gov/view/dot/3588','DOTNTL'); return false;" href="https://rosap.ntl.bts.gov/view/dot/3588"><span>Connected vehicle pilot deployment program phase 1, concept of operations (<span class="hlt">Con</span>Ops) – Tampa (THEA).</span></a></p> <p><a target="_blank" href="http://ntlsearch.bts.gov/tris/index.do">DOT National Transportation Integrated Search</a></p> <p></p> <p>2016-02-01</p> <p>This document describes the Concept of Operations (<span class="hlt">Con</span>Ops) for the Tampa Hillsborough Expressway Authority (THEA) Connected Vehicle (CV) Pilot Deployment. This <span class="hlt">Con</span>Ops describes the current state of operations, establishes the reasons for change, and ...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://rosap.ntl.bts.gov/view/dot/30881','DOTNTL'); return false;" href="https://rosap.ntl.bts.gov/view/dot/30881"><span>Connected vehicle pilot deployment program phase 1, concept of operations (<span class="hlt">Con</span>Ops) - New York City.</span></a></p> <p><a target="_blank" href="http://ntlsearch.bts.gov/tris/index.do">DOT National Transportation Integrated Search</a></p> <p></p> <p>2016-04-08</p> <p>This document describes the Concept of Operations (<span class="hlt">Con</span>Ops) for the New York City Department of Transportation (NYC) Connected Vehicle Pilot Deployment (CVPD) Project. This <span class="hlt">Con</span>Ops describes the current state of operations, establishes the reasons for ...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://files.eric.ed.gov/fulltext/ED501775.pdf','ERIC'); return false;" href="http://files.eric.ed.gov/fulltext/ED501775.pdf"><span>Inclusion: The Pros and <span class="hlt">Cons</span>--A Critical Review</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Savich, Carl</p> <p>2008-01-01</p> <p>The purpose of this paper was to review, analyze, and critique the pros and <span class="hlt">cons</span>, the advantages and disadvantages, of inclusion. The methodology consisted in analyzing and comparing research findings on the benefits and costs of inclusion. Federal legislation and regulations on inclusion were examined, analyzed, and discussed. The results showed…</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_7");'>7</a></li> <li><a href="#" onclick='return showDiv("page_8");'>8</a></li> <li class="active"><span>9</span></li> <li><a href="#" onclick='return showDiv("page_10");'>10</a></li> <li><a href="#" onclick='return showDiv("page_11");'>11</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_9 --> <div id="page_10" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_8");'>8</a></li> <li><a href="#" onclick='return showDiv("page_9");'>9</a></li> <li class="active"><span>10</span></li> <li><a href="#" onclick='return showDiv("page_11");'>11</a></li> <li><a href="#" onclick='return showDiv("page_12");'>12</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="181"> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1997BAAA...41...41G','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1997BAAA...41...41G"><span>Precisión de las velocidades radiales obtenidas <span class="hlt">con</span> el REOSC</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>González, J. F.; Lapasset, E.</p> <p></p> <p>Complementando una línea de trabajo iniciada <span class="hlt">con</span> anterioridad discutimos la estabilidad del espectrógrafo REOSC de CASLEO en DC para la medición de velocidades radiales en base al análisis de observaciones realizadas en enero y abril de 1997. En esas oportunidades obtuvimos 26 espectros de estrellas patrones y 27 espectros de 3 estrellas usadas como estrellas de referencia en nuestro programa de cúmulos abiertos. Además tomamos 26 espectros de crepúsculo <span class="hlt">con</span> el telescopio en posiciones cubriendo el rango H=-4,+4 y δ =-90,+30. Mediante correlaciones cruzadas derivamos la velocidad de 19 órdenes en cada uno de estos espectros. En base a un análisis estadístico de los datos obtenidos discutimos la contribución de los distintos factores que afectan a la dispersión de lectura observada. En particular, la flexión del instrumento no introduciría errores significativos cuando se observa <span class="hlt">con</span> masas de aire menores que 2.0. La dispersión de los valores de velocidad medidos para espectros de alta relación S/N de una misma estrella resultó del orden de 0.5 km/s. La comparación <span class="hlt">con</span> los valores de velocidad publicados por distintos autores para las estrellas patrones no permite distinguir ninguna diferencia sistemática apreciable de las velocidades de CASLEO, siendo la media cuadrática de los residuos del orden de 1.0 km/s.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/20170006879','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/20170006879"><span>Tailoring a <span class="hlt">Con</span>Ops for NASA LSP Integrated Operations</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Owens, Skip Clark V., III</p> <p>2017-01-01</p> <p>An integral part of the Systems Engineering process is the creation of a Concept of Operations (<span class="hlt">Con</span>Ops) for a given system, with the <span class="hlt">Con</span>Ops initially established early in the system design process and evolved as the system definition and design matures. As Integration Engineers in NASA's Launch Services Program (LSP) at Kennedy Space Center (KSC), our job is to manage the interface requirements for all the robotic space missions that come to our Program for a Launch Service. LSP procures and manages a launch service from one of our many commercial Launch Vehicle Contractors (LVCs) and these commercial companies are then responsible for developing the Interface Control Document (ICD), the verification of the requirements in that document, and all the services pertaining to integrating the spacecraft and launching it into orbit. However, one of the systems engineering tools that have not been employed within LSP to date is a Concept of Operations. The goal of this paper is to research the format and content that goes into these various aerospace industry <span class="hlt">Con</span>Ops and tailor the format and content into template form, so the template may be used as an engineering tool for spacecraft integration with future LSP procured launch services. This tailoring effort was performed as the authors final Masters Project in the Spring of 2016 for the Stevens Institute of Technology and modified for publication with INCOSE (Owens, 2016).</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.epa.gov/rodenticides/canceling-some-d-con-mouse-and-rat-control-products','PESTICIDES'); return false;" href="https://www.epa.gov/rodenticides/canceling-some-d-con-mouse-and-rat-control-products"><span>Canceling Some d-<span class="hlt">CON</span> Mouse and Rat Control Products</span></a></p> <p><a target="_blank" href="http://www.epa.gov/pesticides/search.htm">EPA Pesticide Factsheets</a></p> <p></p> <p></p> <p>EPA has reached agreement with the manufacturer, to cancel 12 d-<span class="hlt">CON</span> products that do not meet our testing protocols that better protect children, pets and non-target wildlife from accidental exposure to the pesticide. These products will be phased out.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/18971256','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/18971256"><span>The <span class="hlt">Con</span>Surf-DB: pre-calculated evolutionary conservation profiles of protein structures.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Goldenberg, Ofir; Erez, Elana; Nimrod, Guy; Ben-Tal, Nir</p> <p>2009-01-01</p> <p><span class="hlt">Con</span>Surf-DB is a repository for evolutionary conservation analysis of the proteins of known structures in the Protein Data Bank (PDB). Sequence homologues of each of the PDB entries were collected and aligned using standard methods. The evolutionary conservation of each amino acid position in the alignment was calculated using the Rate4Site algorithm, implemented in the <span class="hlt">Con</span>Surf web server. The algorithm takes into account the phylogenetic relations between the aligned proteins and the stochastic nature of the evolutionary process explicitly. Rate4Site assigns a conservation level for each position in the multiple sequence alignment using an empirical Bayesian inference. Visual inspection of the conservation patterns on the 3D structure often enables the identification of key residues that comprise the functionally important regions of the protein. The repository is updated with the latest PDB entries on a monthly basis and will be rebuilt annually. <span class="hlt">Con</span>Surf-DB is available online at http://consurfdb.tau.ac.il/</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2686473','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2686473"><span>The <span class="hlt">Con</span>Surf-DB: pre-calculated evolutionary conservation profiles of protein structures</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Goldenberg, Ofir; Erez, Elana; Nimrod, Guy; Ben-Tal, Nir</p> <p>2009-01-01</p> <p><span class="hlt">Con</span>Surf-DB is a repository for evolutionary conservation analysis of the proteins of known structures in the Protein Data Bank (PDB). Sequence homologues of each of the PDB entries were collected and aligned using standard methods. The evolutionary conservation of each amino acid position in the alignment was calculated using the Rate4Site algorithm, implemented in the <span class="hlt">Con</span>Surf web server. The algorithm takes into account the phylogenetic relations between the aligned proteins and the stochastic nature of the evolutionary process explicitly. Rate4Site assigns a conservation level for each position in the multiple sequence alignment using an empirical Bayesian inference. Visual inspection of the conservation patterns on the 3D structure often enables the identification of key residues that comprise the functionally important regions of the protein. The repository is updated with the latest PDB entries on a monthly basis and will be rebuilt annually. <span class="hlt">Con</span>Surf-DB is available online at http://consurfdb.tau.ac.il/ PMID:18971256</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28201598','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28201598"><span>A Randomized Phase 2 Study of Long-Acting Trans<span class="hlt">Con</span> GH vs Daily GH in Childhood GH Deficiency.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Chatelain, Pierre; Malievskiy, Oleg; Radziuk, Klaudziya; Senatorova, Ganna; Abdou, Magdy O; Vlachopapadopoulou, Elpis; Skorodok, Yulia; Peterkova, Valentina; Leff, Jonathan A; Beckert, Michael</p> <p>2017-05-01</p> <p>Trans<span class="hlt">Con</span> Growth Hormone (GH) (Ascendis Pharma) is a long-acting recombinant sustained-release human GH prodrug in development for children with GH deficiency (GHD). To compare the pharmacokinetics, pharmacodynamics, safety, and efficacy of weekly Trans<span class="hlt">Con</span> GH to that of daily GH in prepubertal children with GHD. Randomized, open-label, active-controlled study of three doses of weekly Trans<span class="hlt">Con</span> GH versus daily Genotropin (Pfizer). Thirty-eight centers in 14 European countries and Egypt. Prepubertal male and female treatment-naïve children with GHD (n = 53). Subjects received one of three Trans<span class="hlt">Con</span> GH doses (0.14, 0.21, or 0.30 mg GH/kg/wk) or Genotropin 0.03 mg GH/kg/d for 26 weeks. GH and insulinlike growth factor-1 (IGF-1) levels, growth, adverse events, and immunogenicity. Both GH maximum concentration and area under the curve were similar following Trans<span class="hlt">Con</span> GH or Genotropin administration at comparable doses. A dose response was observed, with IGF-1 standard deviation scores increasing into the normal range for all three Trans<span class="hlt">Con</span> GH doses. Annualized mean height velocity for the three Trans<span class="hlt">Con</span> GH doses ranged from 11.9 cm to 13.9 cm, which was not statistically different from 11.6 cm for Genotropin. Adverse events were mild to moderate, and most were unrelated to the study drug. Injection site tolerance was good. One Trans<span class="hlt">Con</span> GH subject developed a low-titer, nonneutralizing antibody response to GH. The results suggest that long-acting Trans<span class="hlt">Con</span> GH is comparable to daily Genotropin for GH (pharmacokinetics) and IGF-1 (pharmacodynamics) levels, safety, and efficacy and support advancement into phase 3 development. Copyright © 2017 Endocrine Society</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://eric.ed.gov/?q=ME&pg=5&id=EJ1032811','ERIC'); return false;" href="https://eric.ed.gov/?q=ME&pg=5&id=EJ1032811"><span>Teaching after Retirement: The Pros and the <span class="hlt">Cons</span></span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Sommer, Robert</p> <p>2014-01-01</p> <p>Having enjoyed teaching during my active career, I continued to teach summer school following retirement. Self-observed sensory and cognitive impairments, although not mentioned by students in their evaluations, induced me to consider the pros and <span class="hlt">cons</span> of continuing to teach. My hope is that this list of benefits and problems will be of assistance…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/CFR-2010-title40-vol23/pdf/CFR-2010-title40-vol23-sec180-1213.pdf','CFR'); return false;" href="https://www.gpo.gov/fdsys/pkg/CFR-2010-title40-vol23/pdf/CFR-2010-title40-vol23-sec180-1213.pdf"><span>40 CFR 180.1213 - Coniothyrium minitans strain <span class="hlt">CON</span>/M/91-08; exemption from the requirement of a tolerance.</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collectionCfr.action?selectedYearFrom=2010&page.go=Go">Code of Federal Regulations, 2010 CFR</a></p> <p></p> <p>2010-07-01</p> <p>... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Coniothyrium minitans strain <span class="hlt">CON</span>/M/91... PESTICIDE CHEMICAL RESIDUES IN FOOD Exemptions From Tolerances § 180.1213 Coniothyrium minitans strain <span class="hlt">CON</span>/M... tolerance is established for residues of the microbial pesticide Coniothyrium minitans strain <span class="hlt">CON</span>/M/91-08...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/CFR-2011-title40-vol24/pdf/CFR-2011-title40-vol24-sec180-1213.pdf','CFR2011'); return false;" href="https://www.gpo.gov/fdsys/pkg/CFR-2011-title40-vol24/pdf/CFR-2011-title40-vol24-sec180-1213.pdf"><span>40 CFR 180.1213 - Coniothyrium minitans strain <span class="hlt">CON</span>/M/91-08; exemption from the requirement of a tolerance.</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collectionCfr.action?selectedYearFrom=2011&page.go=Go">Code of Federal Regulations, 2011 CFR</a></p> <p></p> <p>2011-07-01</p> <p>... 40 Protection of Environment 24 2011-07-01 2011-07-01 false Coniothyrium minitans strain <span class="hlt">CON</span>/M/91... PESTICIDE CHEMICAL RESIDUES IN FOOD Exemptions From Tolerances § 180.1213 Coniothyrium minitans strain <span class="hlt">CON</span>/M... tolerance is established for residues of the microbial pesticide Coniothyrium minitans strain <span class="hlt">CON</span>/M/91-08...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28901589','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28901589"><span>The Sub<span class="hlt">Cons</span> webserver: A user friendly web interface for state-of-the-art subcellular localization prediction.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Salvatore, M; Shu, N; Elofsson, A</p> <p>2018-01-01</p> <p>Sub<span class="hlt">Cons</span> is a recently developed method that predicts the subcellular localization of a protein. It combines predictions from four predictors using a Random Forest classifier. Here, we present the user-friendly web-interface implementation of Sub<span class="hlt">Cons</span>. Starting from a protein sequence, the server rapidly predicts the subcellular localizations of an individual protein. In addition, the server accepts the submission of sets of proteins either by uploading the files or programmatically by using command line WSDL API scripts. This makes Sub<span class="hlt">Cons</span> ideal for proteome wide analyses allowing the user to scan a whole proteome in few days. From the web page, it is also possible to download precalculated predictions for several eukaryotic organisms. To evaluate the performance of Sub<span class="hlt">Cons</span> we present a benchmark of LocTree3 and Sub<span class="hlt">Cons</span> using two recent mass-spectrometry based datasets of mouse and drosophila proteins. The server is available at http://subcons.bioinfo.se/. © 2017 The Protein Society.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/20232594','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/20232594"><span>Somatic cell nuclear transfer: pros and <span class="hlt">cons</span>.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Sumer, Huseyin; Liu, Jun; Tat, Pollyanna; Heffernan, Corey; Jones, Karen L; Verma, Paul J</p> <p>2009-01-01</p> <p>Even though the technique of mammalian SCNT is just over a decade old it has already resulted in numerous significant advances. Despite the recent advances in the reprogramming field, SCNT remains the bench-mark for the generation of both genetically unmodified autologous pluripotent stem cells for transplantation and for the production of cloned animals. In this review we will discuss the pros and <span class="hlt">cons</span> of SCNT, drawing comparisons with other reprogramming methods.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.fs.usda.gov/treesearch/pubs/41995','TREESEARCH'); return false;" href="https://www.fs.usda.gov/treesearch/pubs/41995"><span>Conserva a Puerto Rico <span class="hlt">con</span> bosques maderables</span></a></p> <p><a target="_blank" href="http://www.fs.usda.gov/treesearch/">Treesearch</a></p> <p>Frank H. Wadsworth</p> <p>2009-01-01</p> <p>[article in Spanish] Puerto Rico consume muchos productos forestales costosos de importar. También tiene bosques extensos <span class="hlt">con</span> maderas explotables. Además, existen condiciones físicas favorables para la producción de madera útil. No obstante, hoy día no se utiliza la madera de los bosques actuales ocurre la deforestación para cualquier fin. Los Bosques productivos de...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3711750','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3711750"><span>DESAFÍOS ÉTICOS DE LA INVESTIGACIÓN <span class="hlt">CON</span> ANIMALES, MANIPULACIÓN GENÉTICA</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Yunta, Eduardo Rodríguez</p> <p>2012-01-01</p> <p>En la investigación <span class="hlt">con</span> animales existen cuestionamientos éticos tanto en el uso como modelos de enfermedades humanas y requisito previo para ensayos en humanos como en la introducción de modificaciones genéticas. Algunos de estos cuestionamientos son: no representar exactamente la condición humana como modelos, realizar pruebas de toxicidad <span class="hlt">con</span> grave daño para los animales, alterar su naturaleza mediante modificaciones genéticas, riesgos de la introducción de organismos genéticamente modificados. El uso de animales en investigación para beneficio humano, impone al ser humano la responsabilidad moral de respetarlo, no haciéndoles sufrir innecesariamente, al estar trabajando <span class="hlt">con</span> seres vivientes y sentientes. PMID:23338641</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/servlets/purl/6673953','SCIGOV-STC'); return false;" href="https://www.osti.gov/servlets/purl/6673953"><span><span class="hlt">Con</span> Edison power failure of July 13 and 14, 1977. Final staff report</span></a></p> <p><a target="_blank" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a></p> <p>None</p> <p>1978-06-01</p> <p>On July 13, 1977 the entire electric load of the <span class="hlt">Con</span> Edison system was lost, plunging New York City and Westchester County into darkness. The collapse resulted from a combination of natural events, equipment malfunctions, questionable system-design features, and operating errors. An attempt is made in this report to answer the following: what were the specific causes of the failure; if equipment malfunctions and operator errors contributed, could they have been prevented; to what extent was <span class="hlt">Con</span> Edison prepared to handle such an emergency; and did <span class="hlt">Con</span> Edison plan prudently reserve generation, for reserve transmission capability, for automatic equipment tomore » protect its system, and for proper operator response to a critical situation. Following the introductory and summary section, additional sections include: the Consolidated Edison system; prevention of bulk power-supply interruptions; the sequence of failure and restoration; analysis of the July 1977 power failure; restoration sequence and equipment damage assessment; and other investigations of the blackout. (MCW)« less</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/11246808','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/11246808"><span>Providers debate pros and <span class="hlt">cons</span> of pneumonia vaccination at discharge.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p></p> <p>2001-02-01</p> <p>When to vaccinate against pneumonia? Does it makes sense when patients are in the hospital? Or should patients wait for the first post-op visit with the PCP? Office-based and hospital-based physicians weigh the pros and <span class="hlt">cons</span> of each.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4104142','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4104142"><span>Cue-based assertion classification for Swedish clinical text – developing a lexicon for py<span class="hlt">Con</span>TextSwe</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Velupillai, Sumithra; Skeppstedt, Maria; Kvist, Maria; Mowery, Danielle; Chapman, Brian E.; Dalianis, Hercules; Chapman, Wendy W.</p> <p>2014-01-01</p> <p>Objective The ability of a cue-based system to accurately assert whether a disorder is affirmed, negated, or uncertain is dependent, in part, on its cue lexicon. In this paper, we continue our study of porting an assertion system (py<span class="hlt">Con</span>TextNLP) from English to Swedish (py<span class="hlt">Con</span>TextSwe) by creating an optimized assertion lexicon for clinical Swedish. Methods and material We integrated cues from four external lexicons, along with generated inflections and combinations. We used subsets of a clinical corpus in Swedish. We applied four assertion classes (definite existence, probable existence, probable negated existence and definite negated existence) and two binary classes (existence yes/no and uncertainty yes/no) to py<span class="hlt">Con</span>TextSwe. We compared py<span class="hlt">Con</span>TextSwe’s performance with and without the added cues on a development set, and improved the lexicon further after an error analysis. On a separate evaluation set, we calculated the system’s final performance. Results Following integration steps, we added 454 cues to py<span class="hlt">Con</span>TextSwe. The optimized lexicon developed after an error analysis resulted in statistically significant improvements on the development set (83% F-score, overall). The system’s final F-scores on an evaluation set were 81% (overall). For the individual assertion classes, F-score results were 88% (definite existence), 81% (probable existence), 55% (probable negated existence), and 63% (definite negated existence). For the binary classifications existence yes/no and uncertainty yes/no, final system performance was 97%/87% and 78%/86% F-score, respectively. Conclusions We have successfully ported py<span class="hlt">Con</span>TextNLP to Swedish (py<span class="hlt">Con</span>TextSwe). We have created an extensive and useful assertion lexicon for Swedish clinical text, which could form a valuable resource for similar studies, and which is publicly available. PMID:24556644</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA563140','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA563140"><span>An Application of <span class="hlt">Con</span>-Resistant Trust to Improve the Reliability of Special Protection Systems within the Smart Grid</span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>2012-06-01</p> <p>in an effort to be more reliable and efficient. However, with the benefits of this new technology comes added risk . This research utilizes a <span class="hlt">con</span> ...AN APPLICATION OF <span class="hlt">CON</span> -RESISTANT TRUST TO IMPROVE THE RELIABILITY OF SPECIAL PROTECTION SYSTEMS WITHIN THE SMART GRID THESIS Crystal M. Shipman...Government and is not subject to copyright protection in the United States AFIT/GCO/ENG/12-22 AN APPLICATION OF <span class="hlt">CON</span> -RESISTANT TRUST TO IMPROVE THE</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/21778533','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/21778533"><span>Gestational surrogacy: could be a way to be a way to reproduction? Pros and <span class="hlt">cons</span>.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Clementina, Peris</p> <p>2011-06-01</p> <p>The aim of this article was to address pros and <span class="hlt">cons</span> of gestational surrogacy, the social and psychological issues involved in surrogate motherhood triads. Pros and <span class="hlt">cons</span> of surrogacy, the possible insurgence of a hematologic disease in the fetus, hemolytic disease of the newborn, naturally acquired microchimerism in surrogacy cases, ethical, medical, psychologic, legal and religious issues of a problem are discussed.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/18656072','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/18656072"><span>Young women's perspective of the pros and <span class="hlt">cons</span> to seeking screening for chlamydia and gonorrhea: an exploratory study.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Chacko, Mariam R; von Sternberg, Kirk; Velasquez, Mary M; Wiemann, Constance M; Smith, Peggy B; DiClemente, Ralph</p> <p>2008-08-01</p> <p>To identify young women's pros and <span class="hlt">cons</span> (decisional balance) to seeking chlamydia (CT) and gonorrhea (NGC) screening. Prospective, cross sectional study Community-based reproductive health clinic 192 young women (66% African American; mean age 18.9 years). Content analysis of responses obtained during a decisional balance exercise (pros and <span class="hlt">cons</span>) promoting CT and NGC screening was conducted. Thematic categories were developed through a coding process, and each response was assigned to one thematic category. The frequency of pros and <span class="hlt">cons</span> responses for each category and the frequency of participants endorsing each category were calculated. Ten thematic categories in relation to pros and <span class="hlt">cons</span> of seeking CT and NGC screening were: being healthy; awareness of the body; systemic factors around the clinic visit and testing procedures; benefits and aversions around treatment; partner trust issues; confidentiality; prevention of long term adverse effects, protection of the body; concern for others; fear of results/aversion to testing; and logistical barriers. The three most often cited pros were awareness of the body, being healthy and treatment issues; and the three most often cited <span class="hlt">cons</span> were logistical barriers (time/transportation), fear/aversion to testing, and systemic factors. A variety of pros and <span class="hlt">cons</span> to seeking CT and NGC screening were identified at a community-based clinic. Providers in clinical settings can utilize this information when encouraging patients to seek regular STI screening by elucidating and emphasizing those pros and <span class="hlt">cons</span> that have the most influence on a young woman's decision-making to seek screening.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://espanol.epa.gov/control-de-plagas/utilice-en-forma-segura-los-productos-con-cebo-para-roedores','PESTICIDES'); return false;" href="https://espanol.epa.gov/control-de-plagas/utilice-en-forma-segura-los-productos-con-cebo-para-roedores"><span>Utilice en forma segura los productos <span class="hlt">con</span> cebo para roedores</span></a></p> <p><a target="_blank" href="http://www.epa.gov/pesticides/search.htm">EPA Pesticide Factsheets</a></p> <p></p> <p></p> <p>Si se usan de manera inadecuada, los productos <span class="hlt">con</span> veneno para ratas y ratones podrían hacerle daño a usted, a sus hijos o a sus mascotas. Siempre que use pesticidas lea la etiqueta del producto y siga todas las indicaciones.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_8");'>8</a></li> <li><a href="#" onclick='return showDiv("page_9");'>9</a></li> <li class="active"><span>10</span></li> <li><a href="#" onclick='return showDiv("page_11");'>11</a></li> <li><a href="#" onclick='return showDiv("page_12");'>12</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_10 --> <div id="page_11" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_9");'>9</a></li> <li><a href="#" onclick='return showDiv("page_10");'>10</a></li> <li class="active"><span>11</span></li> <li><a href="#" onclick='return showDiv("page_12");'>12</a></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="201"> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26923569','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26923569"><span>Single step purification of concanavalin A (<span class="hlt">Con</span> A) and bio-sugar production from jack bean using glucosylated magnetic nano matrix.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Kim, Ho Myeong; Cho, Eun Jin; Bae, Hyeun-Jong</p> <p>2016-08-01</p> <p>Jack bean (JB, Canavalia ensiformis) is the source of bio-based products, such as proteins and bio-sugars that contribute to modern molecular biology and biomedical research. In this study, the use of jack bean was evaluated as a source for concanavalin A (<span class="hlt">Con</span> A) and bio-sugar production. A novel method for purifying <span class="hlt">Con</span> A from JBs was successfully developed using a glucosylated magnetic nano matrix (GMNM) as a physical support, which facilitated easy separation and purification of <span class="hlt">Con</span> A. In addition, the enzymatic conversion rate of 2% (w/v) <span class="hlt">Con</span> A extracted residue to bio-sugar was 98.4%. Therefore, this new approach for the production of <span class="hlt">Con</span> A and bio-sugar is potentially useful for obtaining bio-based products from jack bean. Copyright © 2016 Elsevier Ltd. All rights reserved.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/2945865','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/2945865"><span>The role of the 2H4 molecule in the generation of suppressor function in <span class="hlt">Con</span> A-activated T cells.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Morimoto, C; Letvin, N L; Rudd, C E; Hagan, M; Takeuchi, T; Schlossman, S F</p> <p>1986-11-15</p> <p>The molecular basis for the suppression generated in a concanavalin A (<span class="hlt">Con</span> A)-activated T cell culture remains unknown. In this study, we have attempted to determine whether the 2H4 and 4B4 molecules on <span class="hlt">Con</span> A-activated T cells play some role in the generation of suppression by such cells. We have shown that <span class="hlt">Con</span> A-activated suppressor cells belong to the 2H4+ subset of T cells but not the 4B4+ (2H4-) subset. <span class="hlt">Con</span> A-activated T cells exerted their optimal suppressor function on day 2 in culture, a time at which the expression of 2H4 on such cells was maximal and 4B4 was minimal. Furthermore, the stimulation of T cells with the higher concentration of <span class="hlt">Con</span> A generated the stronger suppressor function. At the same time, both 2H4 expression and density were increased and 4B4 expression and density were decreased on such <span class="hlt">Con</span> A-activated T cells. More importantly, the treatment of <span class="hlt">Con</span> A-activated T cells with anti-2H4 antibody but not with anti-4B4, anti-TQ1, or anti-T4 antibodies can block the suppressor function of such cells. Taken together, the above results strongly suggest that the 2H4 molecule itself may be involved in the generation of suppressor function in <span class="hlt">Con</span> A-activated T cells. The 2H4 antigen on such cells was shown to be comprised of 220,000 and 200,000 m.w. glycoproteins. Thus this study indicates that the 220,000 and 200,000 m.w. structure of the 2H4 molecule may itself play a crucial role in the generation of suppressor signals of <span class="hlt">Con</span> A-activated cells.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4600969','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4600969"><span>Hacia el consumo informado de tabaco en México: efecto de las advertencias <span class="hlt">con</span> pictogramas en población fumadora</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Thrasher, James F; Pérez-Hernández, Rosaura; Arillo-Santillán, Edna; Barrientos-Gutiérrez, Inti</p> <p>2015-01-01</p> <p>Resumen Objetivo Evaluar el efecto de las advertencias sanitarias (AS) <span class="hlt">con</span> pictogramas en las cajetillas de tabaco en adultos fumadores. Material y métodos Cohorte de fumadores <span class="hlt">con</span> representatividad poblacional de siete ciudades mexi canas, antes (2010) y después (2011) de la implementación de AS <span class="hlt">con</span> pictogramas (ASP). Para determinar el cambio en las variables sobre el impacto cognitivo y conductual de las advertencias, se estimaron modelos bivariados y ajustados de ecuaciones de estimación generalizada. En el Segundo levantamiento (2011), se estimaron modelos para determiner los factores que se asocian <span class="hlt">con</span> el reporte de recordar cada advertencia que había entrado al mercado, además de los factores asociados <span class="hlt">con</span> el autorreporte del impacto de cada advertencia vigente. Resultados Se observaron incrementos importantes de 2010 a 2011 en los conocimientos sobre los riesgos de fumar, los componentes tóxicos del tabaco y el número telefónico para recibir consejos sobre dejar de fumar. La recordación e impacto de las primeras advertencias <span class="hlt">con</span> pictogramas parecen ser amplios y equitativos a través de la población fumadora. En comparación <span class="hlt">con</span> 2010, un mayor nivel de ex fumadores entrevistados en 2011 reportaron que las advertencias habían influido mucho en dejar de fumar (RM=2.44, 95% IC 1.27–4.72). Conclusiones Las AS <span class="hlt">con</span> pictogramas han logrado un impacto importante en el conocimiento y conducta, información relevante para la población y en tomadores de decisiones. PMID:22689162</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26786174','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26786174"><span>Self-efficacy, pros, and <span class="hlt">cons</span> as variables associated with adjacent stages of change for regular exercise in Japanese college students.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Horiuchi, Satoshi; Tsuda, Akira; Kobayashi, Hisanori; Fallon, Elizabeth A; Sakano, Yuji</p> <p>2017-07-01</p> <p>This study examined self-efficacy (confidence to exercise), pros (exercise's advantages), and <span class="hlt">cons</span> (exercise's disadvantages) as variables associated across the transtheoretical model's six stages of change in 403 Japanese college students. A series of logistic regression analyses were conducted. Results showed that higher pros and lower <span class="hlt">cons</span> were associated with being in contemplation compared to precontemplation. Lower <span class="hlt">cons</span> were associated with being in preparation compared to contemplation. Higher self-efficacy was associated with being in action compared to preparation as well as being in maintenance compared to action. Lower <span class="hlt">cons</span> were associated with being in termination compared to maintenance.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3170997','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3170997"><span>Changes to perceptions of the pros and <span class="hlt">cons</span> of genetic susceptibility testing after APOE genotyping for Alzheimer disease risk</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Christensen, Kurt D.; Roberts, J. Scott; Uhlmann, Wendy R.; Green, Robert C.</p> <p>2011-01-01</p> <p>Purpose Perceptions about the pros and <span class="hlt">cons</span> of genetic susceptibility testing are among the best predictors of test utilization. How actual testing changes such perceptions has yet to be examined. Methods In a clinical trial, first-degree relatives of patients with Alzheimer disease received genetic risk assessments for Alzheimer disease including APOE disclosure. Participants rated 11 possible benefits associated with genetic testing (pros) and 10 risks or limitations (<span class="hlt">cons</span>) before genetic risk disclosure and again 12 months afterward. Results Pros were rated higher than <span class="hlt">cons</span> at baseline (3.53 vs. 1.83, P < 0.001) and at 12 months after risk disclosure (3.33 vs. 1.88, P < 0.001). Ratings of pros decreased during the 12-month period (3.33 vs. 3.53, P < 0.001). Ratings of <span class="hlt">cons</span> did not change (1.88 vs. 1.83, P = 0.199) except for a three-item discrimination subscale which increased (2.07 vs. 1.92, P = 0.012). Among specific pros and <span class="hlt">cons</span>, three items related to prevention and treatment changed the most. Conclusion The process of APOE genetic risk assessment for Alzheimer disease sensitizes some to its limitations and the risks of discrimination; however, 1-year after disclosure, test recipients still consider the pros to strongly outweigh the <span class="hlt">cons</span>. PMID:21270636</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3929905','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3929905"><span>Perceived pros and <span class="hlt">cons</span> of smoking and quitting in hard-core smokers: a focus group study</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p></p> <p>2014-01-01</p> <p>Background In the last decade, so-called hard-core smokers have received increasing interest in research literature. For smokers in general, the study of perceived costs and benefits (or ‘pros and cons’) of smoking and quitting is of particular importance in predicting motivation to quit and actual quitting attempts. Therefore, this study aims to gain insight into the perceived pros and <span class="hlt">cons</span> of smoking and quitting in hard-core smokers. Methods We conducted 11 focus group interviews among current hard-core smokers (n = 32) and former hard-core smokers (n = 31) in the Netherlands. Subsequently, each participant listed his or her main pros and <span class="hlt">cons</span> in a questionnaire. We used a structural procedure to analyse the data obtained from the group interviews and from the questionnaires. Results Using the qualitative data of both the questionnaires and the transcripts, the perceived pros and <span class="hlt">cons</span> of smoking and smoking cessation were grouped into 6 main categories: Finance, Health, Intrapersonal Processes, Social Environment, Physical Environment and Food and Weight. Conclusions Although the perceived pros and <span class="hlt">cons</span> of smoking in hard-core smokers largely mirror the perceived pros and <span class="hlt">cons</span> of quitting, there are some major differences with respect to weight, social integration, health of children and stress reduction, that should be taken into account in clinical settings and when developing interventions. Based on these findings we propose the ‘Distorted Mirror Hypothesis’. PMID:24548463</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2582049','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2582049"><span>YOUNG WOMEN’S PERSPECTIVE OF THE PROS AND <span class="hlt">CONS</span> TO SEEKING SCREENING FOR CHLAMYDIA AND GONORRHEA: AN EXPLORATORY STUDY</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Chacko, Mariam R.; von Sternberg, Kirk; Velasquez, Mary M.; Wiemann, Constance M.; Smith, Peggy B.; DiClemente, Ralph</p> <p>2008-01-01</p> <p>Study Objective To identify young women’s pros and <span class="hlt">cons</span> (decisional balance) to seeking chlamydia (CT) and gonorrhea (NGC) screening. Design Prospective, cross sectional study Setting Community-based reproductive health clinic Participants 192 young women (66% African American; mean age 18.9 years). Main Outcome Measure(s) Content analysis of responses obtained during a decisional balance exercise (pros and <span class="hlt">cons</span>) promoting CT and NGC screening was conducted. Thematic categories were developed through a coding process, and each response was assigned to one thematic category. The frequency of pros and <span class="hlt">cons</span> responses for each category and the frequency of participants endorsing each category were calculated. Results Ten thematic categories in relation to pros and <span class="hlt">cons</span> of seeking CT and NGC screening were: being healthy; awareness of knowing the body; systemic factors around the clinic visit and testing procedures; benefits and aversions around treatment; partner relationship issues; confidentiality; prevention of long term adverse effects, protection of the body; concern for others; fear of results/aversion to testing; and logistical barriers. The three most often cited pros were awareness, healthy and treatment issues; and the three most often cited <span class="hlt">cons</span> were logistical barriers (time/transportation), fear/aversion to testing, and systemic issues. Conclusions A variety of pros and <span class="hlt">cons</span> to seeking CT and NGC screening were identified at a community-based clinic. Providers in clinical settings can utilize this information when encouraging patients to seek regular STI screening by elucidating and emphasizing those pros and <span class="hlt">cons</span> that have the most influence on a young woman’s decision-making to seek screening. PMID:18656072</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015IAUGA..2257449H','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015IAUGA..2257449H"><span>CHILES <span class="hlt">Con</span> Pol: An ultra-deep JVLA survey probing galaxy evolution and cosmic magnetism</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Hales, Christopher A.; Momjian, Emmanuel; van Gorkom, Jacqueline; Rupen, Michael P.; Greiner, Maksim; Ensslin, Torsten A.; Bonzini, Margherita; Padovani, Paolo; Harrison, Ian; Brown, Michael L.; Gim, Hansung; Yun, Min S.; Maddox, Natasha; Stewart, Adam; Fender, Rob P.; Tremou, Evangelia; Chomiuk, Laura; Peters, Charee; Wilcots, Eric M.; Lazio, Joseph</p> <p>2015-08-01</p> <p>We are undertaking a 1000 hour campaign with the Karl G. Jansky VLA to survey 0.2 square degrees of the COSMOS field in full polarization continuum at 1.4 GHz. Our observations are part of a joint program with the spectral line COSMOS HI Large Extragalactic Survey (CHILES). When complete, we expect our CHILES Continuum Polarization (CHILES <span class="hlt">Con</span> Pol) survey to reach an SKA-era sensitivity of 500 nJy per 4 arcsecond resolving beam, the deepest view of the radio sky yet. CHILES <span class="hlt">Con</span> Pol will open new and fertile parameter space, with sensitivity to star formation rates of 10 Msun per year out to an unprecedented redshift of z=2, and ultra-luminous infrared galaxies and sub-millimeter galaxies out to redshifts of z=8 and beyond. This rich resource will extend the utility of radio band studies beyond the usual radio quasar and radio galaxy populations, opening sensitivity to the starforming and radio-quiet AGN populations that form the bulk of extragalactic sources detected in the optical, X-ray, and infrared bands. In this talk I will outline the key science of CHILES <span class="hlt">Con</span> Pol, including galaxy evolution and novel measurements of intergalactic magnetic fields. I will present initial results from the first 180 hours of the survey and describe our forthcoming Data Release 1. I invite the astronomical community to consider unique science that can be pursued with CHILES <span class="hlt">Con</span> Pol radio data.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.nrel.gov/news/program/2017/nrel-nyserda-conedison-partner-hems.html','SCIGOVWS'); return false;" href="https://www.nrel.gov/news/program/2017/nrel-nyserda-conedison-partner-hems.html"><span>NREL, NYSERDA, and <span class="hlt">Con</span> Edison Partner on Home Energy Management Systems |</span></a></p> <p><a target="_blank" href="http://www.science.gov/aboutsearch.html">Science.gov Websites</a></p> <p></p> <p></p> <p>at large scale, the overall impact could be a <em>win</em>-<em>win</em> for both homeowners and utilities, which could sources. Founded in 1823, <span class="hlt">Con</span> Edison provides electric, gas, and steam service to 10 million <em>people</em> who</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://images.nasa.gov/#/details-PIA15017.html','SCIGOVIMAGE-NASA'); return false;" href="https://images.nasa.gov/#/details-PIA15017.html"><span>NASA Satellite Tracks Underwater Volcanic Eruption in Canary Islands</span></a></p> <p><a target="_blank" href="https://images.nasa.gov/">NASA Image and Video Library</a></p> <p></p> <p>2011-11-02</p> <p>In July 2011, volcanic tremors began on the Island of El <span class="hlt">Hierro</span> in the Canary Islands; by September, many tourists evacuated the resort island, fearing a volcanic eruption. This image is from NASA Terra spacecraft.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28693029','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28693029"><span>Angio-OCT de la zona avascular foveal en ojos <span class="hlt">con</span> oclusión venosa de la retina.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Wons, Juliana; Pfau, Maximilian; Wirth, Magdalena A; Freiberg, Florentina J; Becker, Matthias D; Michels, Stephan</p> <p>2017-07-11</p> <p>Objetivo: El objetivo del estudio comprendía visualizar y cuantificar las alteraciones patológicas de la zona avascular foveal (ZAF) mediante angio-OCT en ojos <span class="hlt">con</span> oclusión venosa de la retina (OVR) en comparación <span class="hlt">con</span> el ojo contralateral sano. Procedimientos: La angio-OCT se llevó a cabo mediante el sistema Avanti® RTVue 100 XR (Optovue Inc., Fremont, Calif., EE. UU.). Los bordes de la capa vascular superficial (CVS) se definieron como 3 μm por debajo de la membrana limitante interna y 15 μm por debajo de la capa plexiforme interna y, para la capa vascular profunda (CVP), como 15 y 70 μm por debajo de la membrana limitante interna y de la capa plexiforme interna, respectivamente. La longitud de la ZAF horizontal, vertical y máxima de la CVS y la CVP en cada ojo se midió de forma manual. Además, se midió el ángulo entre el diámetro máximo de la ZAF y el plano papilomacular. Resultados: La angio-OCT representó los defectos dentro de la vasculatura en el área perifoveal en ojos <span class="hlt">con</span> oclusión de rama venosa de la retina (ORVR; n = 11) y <span class="hlt">con</span> oclusión de la vena central de la retina (OVCR; n = 8). Esto resultó en un crecimiento del diámetro máximo de la ZAF en ojos <span class="hlt">con</span> OVR (n = 19) en comparación <span class="hlt">con</span> el ojo contralateral (n = 19; 921 ± 213 frente a 724 ± 145 µm; p = 0,008). Además, se observó una correlación significativa entre la mejor agudeza visual corregida (MAVC) y el diámetro máximo de la ZAF en la CVP (ρ de Spearman = -0,423, p < 0,01). Por último, en los ojos <span class="hlt">con</span> OVR, el ángulo entre el plano papilomacular y el diámetro máximo de la ZAF se dio tan solo en el 21,05% (CVS) y en el 15,79% (CVP) de los casos a 0 ± 15 ó 90 ± 15°, respectivamente. En ojos sanos, estos ángulos (que supuestamente representan una configuración de la ZAF regular) fueron más prevalentes (CVS 68,42 frente a 21,05%, p = 0,003; CVP 73,68 frente a 15,79%, p < 0,001). Conclusiones: La angio-OCT muestra alteraciones morfológicas de la ZAF en ojos <span class="hlt">con</span></p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://epi.grants.cancer.gov/iconfirm/','NCI'); return false;" href="https://epi.grants.cancer.gov/iconfirm/"><span>The International Consortium for the Investigation of Renal Malignancies (I-<span class="hlt">Con</span>FIRM)</span></a></p> <p><a target="_blank" href="http://www.cancer.gov">Cancer.gov</a></p> <p></p> <p></p> <p>The International Consortium for the Investigation of Renal Malignancies (I-<span class="hlt">Con</span>FIRM) was formed to promote international, multidisciplinary collaborations to advance our understanding of the etiology and outcomes of kidney cancer.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.loc.gov/pictures/collection/hh/item/cz0044.photos.579137p/','SCIGOV-HHH'); return false;" href="https://www.loc.gov/pictures/collection/hh/item/cz0044.photos.579137p/"><span>Detail of <span class="hlt">conning</span> tower atop the submarine. Note the wire ...</span></a></p> <p><a target="_blank" href="http://www.loc.gov/pictures/collection/hh/">Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey</a></p> <p></p> <p></p> <p>Detail of <span class="hlt">conning</span> tower atop the submarine. Note the wire rope wrapped around the base of the tower, which may have been used in an attempt to pull the submarine offshore. - Sub Marine Explorer, Located along the beach of Isla San Telmo, Pearl Islands, Isla San Telmo, Former Panama Canal Zone, CZ</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://eric.ed.gov/?q=end+AND+user+AND+interfaces&pg=7&id=EJ363755','ERIC'); return false;" href="https://eric.ed.gov/?q=end+AND+user+AND+interfaces&pg=7&id=EJ363755"><span>End-User Use of Data Base Query Language: Pros and <span class="hlt">Cons</span>.</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Nicholes, Walter</p> <p>1988-01-01</p> <p>Man-machine interface, the concept of a computer "query," a review of database technology, and a description of the use of query languages at Brigham Young University are discussed. The pros and <span class="hlt">cons</span> of end-user use of database query languages are explored. (Author/MLW)</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5799940','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5799940"><span>Papiloma invertido sinunasal <span class="hlt">con</span> invasión intracraneal: Reporte de caso y revisión bibliográfica</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Di Pietrantonio, Andrés; Asmus, Humberto; Ingratta, Christian; Brennan, Walter; Schulz, Javier; Carballo, Leandro</p> <p>2018-01-01</p> <p>Resumen IntroducciÓn: El papiloma invertido es una neoplasia benigna de los senos paranasales localmente agresiva <span class="hlt">con</span> alto potencial de recurrencia y de malignización. La extensión intracraneal es infrecuente y más aún, la penetración dural, asociándose a menudo a la recurrencia de la enfermedad o a su degeneración en carcinoma de células escamosas. Caso clínico: Presentamos el caso de una paciente de 32 años que consultó por lesión exofítica en fosa nasal derecha y exoftalmos, asociada a cefalea, anosmia y disgeusia. Se estudió <span class="hlt">con</span> TC cerebro, macizo facial y RM de encéfalo que evidencian lesión en fosa nasal derecha <span class="hlt">con</span> ocupación de senos aéreos, osteólisis de pared medial orbitaria y base de cráneo anterior e invasión intracraneal frontal derecha, <span class="hlt">con</span> efecto de masa y compresión del parénquima encefálico adyacente. Intervención: Se realizó una nasofibroscopía en primer tiempo <span class="hlt">con</span> diagnóstico anatomopatológico de papiloma invertido y posteriormente resección de la lesión mediante doble abordaje más reconstrucción de la fosa craneal anterior. Se obtuvo diagnóstico definitivo de papiloma invertido de tipo Schneideriano <span class="hlt">con</span> áreas de transformación atípica in situ. La paciente evolucionó de forma favorable y sin complicaciones, <span class="hlt">con</span> permeabilidad de vía aérea superior, sin signos de recidiva lesional luego de 4 años de seguimiento. Conclusión: La invasión intracraneal de esta patología es sumamente infrecuente. Cuando existe, es indicador de agresividad y potencial recidiva, por lo que la exéresis completa de la misma define el pronóstico de la enfermedad. PMID:29430328</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4431996','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4431996"><span>Prevalencia y tamizaje del Trastorno por Déficit de Atención <span class="hlt">con</span> Hiperactividad en Costa Rica</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Weiss, Nicholas T.; Schuler, Jovita; Monge, Silvia; McGough, James J.; Chavira, Denise; Bagnarello, Monica; Herrera, Luis Diego; Mathews, Carol A.</p> <p>2015-01-01</p> <p>Resumen La investigación tuvo como propósito estimar la prevalencia del Trastorno por Déficit de Atención <span class="hlt">con</span> Hiperactividad (TDAH) en Costa Rica y determinar si la versión en español del cuestionario Swanson Nolan and Pelham Scale IV (SNAP-IV) es un instrumento de tamizaje útil en una población de niños y niñas escolares costarricenses. El instrumento fue entregado a padres y maestros de 425 niños entre 5 y 13 años de edad (promedio = 8.8). Todos fueron evaluados <span class="hlt">con</span> el instrumento Swanson, Kotkin, Agler, M-Flynn and Pelham Scale (SKAMP). Su diagnóstico fue confirmado <span class="hlt">con</span> una entrevista clínica. La sensibilidad y la especificidad del SNAP-IV fueron evaluadas como predictores de criterios de diagnóstico según el DSM-IV. La prevalencia puntual en la muestra del TDAH fue del 5%. El tamizaje más preciso lo hizo el SNAP-IV completado por el maestro en un corte de 20%, <span class="hlt">con</span> una sensibilidad de 96% y una especificidad de un 82%. La sensibilidad de los instrumentos completados por los padres fue más baja que aquella de los maestros. El SNAP-IV completado por las maestras <span class="hlt">con</span> un corte aislando el 20% de los mayores puntajes categorizó correctamente a un 87% de los sujetos. PMID:22432094</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1996BAAA...40R..40R','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1996BAAA...40R..40R"><span>Nuevas observaciones de 3C10 <span class="hlt">con</span> el VLA*: estudio de la expansión</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Reynoso, E. M.; Moffett, D. A.:; Dubner, G. M.; Giacani, E. B.; Reynolds, S. P.; Goss, W. M.; Dickel, J.</p> <p></p> <p>Se presentan nuevos resultados sobre la expansión del remanente de la supernova de Tycho a lo largo de un intervalo de 10.9 años, comparando nuevas observaciones tomadas <span class="hlt">con</span> el VLA a 1375 y 1635 MHz durante 1994 y 1995, <span class="hlt">con</span> observaciones previas realizadas entre 1983 y 1984 (Dickel y col. ~1991 AJ 101, 2151), usando las mismas configuraciones, anchos de banda, calibradores y tiempos de integración. El coeficiente de expansión se calcula para sectores radiales de 4o de ancho cada uno, ajustando la correlación cruzada de las derivadas de los perfiles promedio para cada época. A partir de la expansión medida, se estima el índice (parámetro de expansión) de la ley potencial R∝ tm como m≡ d ln R/d ln t . Este valor se compara <span class="hlt">con</span> coeficientes teóricos para diferentes fases evolutivas de remanentes de supernova.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1998larm.confE..52C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1998larm.confE..52C"><span>Soluciones analiticas AL problema de jets <span class="hlt">con</span> velocidad de eyeccion variable EN EL tiempo.</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Canto, J.; Raga, A. C.; D'Alessio, P.</p> <p>1998-11-01</p> <p>Se presenta un nuevo metodo que permite resolver de manera exacta y analitica las ecuaciones que describen un jet hipersonico <span class="hlt">con</span> velocidad de eyeccion variable en el tiempo. El metodo se basa en consideraciones sencillas de conservacion de momento para las superficies de trabajo que se forman en el interior del jet. Como ejemplo, se presentan soluciones para jets <span class="hlt">con</span> variacion sinusoidal en la velocidad de eyeccion, y tambien para el caso de un incremento lineal en el tiempo. Estas soluciones analiticas tienen una clara aplicacion en la interpretacion de las observaciones de jets asociados a objetos Herbig-Haro.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/20120011953','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/20120011953"><span>Air Traffic Management Technology Demonstration-1 Concept of Operations (ATD-1 <span class="hlt">Con</span>Ops)</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Baxley, Brian T.; Johnson, William C.; Swenson, Harry; Robinson, John E.; Prevot, Thomas; Callantine, Todd; Scardina, John; Greene, Michael</p> <p>2012-01-01</p> <p>The operational goal of the ATD-1 <span class="hlt">Con</span>Ops is to enable aircraft, using their onboard FMS capabilities, to fly Optimized Profile Descents (OPDs) from cruise to the runway threshold at a high-density airport, at a high throughput rate, using primarily speed control to maintain in-trail separation and the arrival schedule. The three technologies in the ATD-1 <span class="hlt">Con</span>Ops achieve this by calculating a precise arrival schedule, using controller decision support tools to provide terminal controllers with speeds for aircraft to fly to meet times at a particular meter points, and onboard software providing flight crews with speeds for the aircraft to fly to achieve a particular spacing behind preceding aircraft.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://eric.ed.gov/?q=ME&pg=3&id=ED577990','ERIC'); return false;" href="https://eric.ed.gov/?q=ME&pg=3&id=ED577990"><span>Existing <span class="hlt">con</span> el Lobo, Traversing la Frontera <span class="hlt">con</span> Mis Nepantla Coyotes, y Buscando la Vida del Zorro: An Autoethnographic Exploration of a Chicano in Academia</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Ramirez, Ernesto Fidel</p> <p>2017-01-01</p> <p>This dissertation is the experience of my life, an evolution of platicas I have had <span class="hlt">con</span> mis coyotes, my Nepantlero guides. I am one Chicano navigating through the mechanisms of a coercive and hegemonic system which limits our advancement in the academy. My ontology, epistemology, and axiology stem from my cultural and family foundations which I…</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_9");'>9</a></li> <li><a href="#" onclick='return showDiv("page_10");'>10</a></li> <li class="active"><span>11</span></li> <li><a href="#" onclick='return showDiv("page_12");'>12</a></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_11 --> <div id="page_12" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_10");'>10</a></li> <li><a href="#" onclick='return showDiv("page_11");'>11</a></li> <li class="active"><span>12</span></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="221"> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25937559','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25937559"><span>Molecular phylogenetics of Micromeria (Lamiaceae) in the Canary Islands, diversification and inter-island colonization patterns inferred from nuclear genes.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Puppo, Pamela; Curto, Manuel; Gusmão-Guedes, Joana; Cochofel, Jaqueline; Pérez de Paz, Pedro Luis; Bräuchler, Christian; Meimberg, Harald</p> <p>2015-08-01</p> <p>Here we reconstruct the evolutionary history of Micromeria in the Canary Islands using eight nuclear markers. Our results show two centers of diversification for Micromeria, one in the eastern islands Gran Canaria and Lanzarote, the other in the western islands, Tenerife, La Palma and El <span class="hlt">Hierro</span>. Suggested directions of inter-island colonization are the following: Gran Canaria to Lanzarote and La Gomera; Tenerife to La Palma (from the paleoisland of Teno), to El <span class="hlt">Hierro</span> (from the younger, central part), and to La Gomera and Madeira (from the paleoislands). Colonization of La Gomera probably occurred several times from Gran Canaria and Tenerife. The taxonomic implications of these results are discussed. Incongruence among the different markers was evaluated and, using next generation sequencing, we investigated if this incongruence is due to gene duplication. Copyright © 2015 Elsevier Inc. All rights reserved.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/3091269','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/3091269"><span>Thymic lymphocytes. III. Cooperative phenomenon in the proliferation of thymocytes under <span class="hlt">Con</span> A stimulation.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Papiernik, M; Jacobson, J B</p> <p>1986-01-01</p> <p>In the present paper, the response of thymocytes to <span class="hlt">Con</span> A is analyzed in terms of a cooperative phenomenon between medullary thymocytes, cortical thymocytes, thymic accessory cells, and interleukin 2. Medullary thymocytes respond spontaneously to <span class="hlt">Con</span> A and produce IL-2. The addition of exogenously produced IL-2 enhances their proliferation. Small numbers of cortical (PNA+) thymocytes do not respond to <span class="hlt">Con</span> A, even in the presence of IL-2-containing supernatant. By increasing the number of PNA+ cells per well, sensitivity to <span class="hlt">Con</span> A and IL-2 appears. This response may be linked either to the increase in a minor PNA+-responding population and/or to the enhanced contamination by medullary thymocytes and macrophages in non-responding PNA+ thymocyte population. In this hypothesis, either the contaminating cells respond by themselves and/or cooperate with PNA+ cells to induce their proliferation. Coculture of non-responding low numbers of PNA+ thymocytes with <span class="hlt">Con</span> A- and IL-2-containing supernatant in the presence of PNA- cells containing thymic medullary thymocytes and macrophages always produces a higher response than that of each individual population. These results show that a cooperative phenomenon occurs in the cocultures of PNA+ and PNA- thymic cells. We can show using PNA+ and PNA- thymocytes with different Thy 1 alleles, that indeed both PNA+ and populations participate PNA-thymocytes with different Thy 1 alleles, that indeed both PNA+ and PNA- populations participate in the generation of proliferating cells. We can demonstrate, by lysis experiments with monoclonal antibodies and complement that at the end of coculture, most of the proliferating cells are Lyt 1+, and part are Lyt 2+ or L3T4+. We discuss the fact that the phenotype of the cells after activation does not allow us to deduce the phenotype of their precursors. Lysis of Ia+ cells prior to coculture, reduces the level of the proliferative response but does not modify the percentage of cooperation produced</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3768475','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3768475"><span>Oxacilin-resistant Coagulase-negative staphylococci (<span class="hlt">CoNS</span>) bacteremia in a general hospital at São Paulo city, Brasil</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>d’Azevedo, P.A.; Secchi, C.; Antunes, A.L.S.; Sales, T.; Silva, F.M.; Tranchesi, R.; Pignatari, A.C.C.</p> <p>2008-01-01</p> <p>In the last decades, coagulase-negative staphylococci (<span class="hlt">CoNS</span>), especially Staphylococcus epidermidis have become an important cause of bloodstream infections. In addition, rates of methicillin-resistance among <span class="hlt">CoNS</span> have increased substantially, leading to the use of glicopeptides for therapy. The objective of this study was to evaluate eleven consecutives clinically relevant cases of oxacillin-resistant <span class="hlt">CoNS</span> bacteremia in a general hospital localized in São Paulo city, Brazil. Five different species were identified by different phenotypic methods, including S. epidermidis (5), S. haemolyticus (3), S. hominis (1), S. warneri (1) and S. cohnii subsp urealyticus (1). A variety of Pulsed Field Gel Electrophoresis profiles was observed by macrorestriction DNA analysis in S. epidermidis isolates, but two of three S. haemolyticus isolates presented the same profile. These data indicated the heterogeneity of the <span class="hlt">CoNS</span> isolates, suggesting that horizontal dissemination of these microorganisms in the investigated hospital was not frequent. One S. epidermidis and one S. haemolyticus isolates were resistant to teicoplanin and susceptible to vancomycin. The selective pressure due to the use of teicoplanin in this hospital is relevant. PMID:24031279</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/CFR-2012-title40-vol26/pdf/CFR-2012-title40-vol26-sec227-27.pdf','CFR2012'); return false;" href="https://www.gpo.gov/fdsys/pkg/CFR-2012-title40-vol26/pdf/CFR-2012-title40-vol26-sec227-27.pdf"><span>40 CFR 227.27 - Limiting permissible <span class="hlt">con</span>-cen-tra-tion (LPC).</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collectionCfr.action?selectedYearFrom=2012&page.go=Go">Code of Federal Regulations, 2012 CFR</a></p> <p></p> <p>2012-07-01</p> <p>... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Limiting permissible <span class="hlt">con</span>-cen-tra-tion... scientific literature or accepted by EPA as being reliable test organisms to determine the anticipated impact... for each type they represent, and that are documented in the scientific literature and accepted by EPA...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2005LPI....36.1014J','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2005LPI....36.1014J"><span>Fast-Turnoff Transient Electromagnetic (TEM) Field Study at the Mars Analog Site of Rio Tinto, Spain</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Jernsletten, J. A.</p> <p>2005-03-01</p> <p>This report describes a Fast-Turnoff Transient Electromagnetic (TEM) study at the Peña de <span class="hlt">Hierro</span> ("Berg of Iron") field area of the Mars Analog Research and Technology Experiment (MARTE), near the towns Rio Tinto and Nerva, Andalucia region, Spain.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25724751','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25724751"><span>Salud mental en desastres naturales: estrategias interventivas <span class="hlt">con</span> adultos mayores en sectores rurales de Chile.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Osorio-Parraguez, Paulina; Espinoza, Adriana</p> <p>2016-06-01</p> <p>En el presente artículo se da a conocer una estrategia de intervención llevada a cabo <span class="hlt">con</span> adultos mayores en la comuna de Paredones, sexta región de Chile, <span class="hlt">con</span> posterioridad al terremoto y tsunami del 27 de febrero 2010 en Chile, en el contexto de una investigación sobre fortalezas y vulnerabilidades desplegadas por este grupo etario, <span class="hlt">con</span> posterioridad a un desastre natural. Se presenta una descripción del desarrollo metodológico de la intervención y de los sustentos teóricos y conceptuales en los que se basa. Como resultado de este proceso, se propone una estrategia que trabaje a través de la identificación de las propias experiencias y fortalezas de los sujetos. De tal forma se minimizan los efectos negativos de los determinantes sociales de la salud (como la edad y el lugar de residencia) en contexto de crisis; permitiendo a los adultos mayores fortalecer sus recursos individuales y colectivos, en pro de su bienestar psicosocial. © The Author(s) 2015.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1998BAAA...42R..15M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1998BAAA...42R..15M"><span>Catálogo de Radio-Fuentes Opticas <span class="hlt">con</span> Astrolabio Fotoeléctrico PAII</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Manrique, W. T.; Podestá, R. C.; Alonso, E.; Actis, E. V.; Pacheco, A. M.; Bustos, G.; Lizhi, L.; Zezhi, W.; Fanmiao, Z.; Hongqi, W.; Perdomo, R.</p> <p></p> <p>Usando los datos observados en San Juan <span class="hlt">con</span> el Astrolabio Fotoeléctrico PAII desde Febrero de 1992 hasta Marzo de 1997, se ha realizado el Catálogo de Radio-Fuentes Opticas de San Juan conteniendo 69 estrellas. Las observaciones de las posiciones de las radio-fuentes están realizadas para la época y equinoccio J2000,0 y en un sistema cercano al del FK5. Las precisiones medias son ± 2,2 ms y ± 0,"035 en ascensión recta y declinación respectivamente. Las magnitudes de las estrellas son desde 0,9 a 10,7 . Las declinaciones son desde --2,5 grados a --60 grados. La época media es 1995,1. Se muestran también los resultados comparados <span class="hlt">con</span> el Catálogo Hiparcos.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4987940','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4987940"><span><span class="hlt">Con</span>Surf 2016: an improved methodology to estimate and visualize evolutionary conservation in macromolecules</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Ashkenazy, Haim; Abadi, Shiran; Martz, Eric; Chay, Ofer; Mayrose, Itay; Pupko, Tal; Ben-Tal, Nir</p> <p>2016-01-01</p> <p>The degree of evolutionary conservation of an amino acid in a protein or a nucleic acid in DNA/RNA reflects a balance between its natural tendency to mutate and the overall need to retain the structural integrity and function of the macromolecule. The <span class="hlt">Con</span>Surf web server (http://consurf.tau.ac.il), established over 15 years ago, analyses the evolutionary pattern of the amino/nucleic acids of the macromolecule to reveal regions that are important for structure and/or function. Starting from a query sequence or structure, the server automatically collects homologues, infers their multiple sequence alignment and reconstructs a phylogenetic tree that reflects their evolutionary relations. These data are then used, within a probabilistic framework, to estimate the evolutionary rates of each sequence position. Here we introduce several new features into <span class="hlt">Con</span>Surf, including automatic selection of the best evolutionary model used to infer the rates, the ability to homology-model query proteins, prediction of the secondary structure of query RNA molecules from sequence, the ability to view the biological assembly of a query (in addition to the single chain), mapping of the conservation grades onto 2D RNA models and an advanced view of the phylogenetic tree that enables interactively rerunning <span class="hlt">Con</span>Surf with the taxa of a sub-tree. PMID:27166375</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://files.eric.ed.gov/fulltext/ED497693.pdf','ERIC'); return false;" href="http://files.eric.ed.gov/fulltext/ED497693.pdf"><span>A National Look at Postmodernism's Pros and <span class="hlt">Cons</span> in Educational Leadership</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Townsell, Rhodena</p> <p>2007-01-01</p> <p>The purpose of this article is to take a look at the pros and <span class="hlt">cons</span> of postmodernism. It is imperative for administrators to closely examine educational theories and practices prior to instituting changes. The ability to read and digest challenging material keeps one informed and prepared to lead effectively. This paper will list the pros and cons…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24067336','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24067336"><span>Depth of origin of magma in eruptions.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Becerril, Laura; Galindo, Ines; Gudmundsson, Agust; Morales, Jose Maria</p> <p>2013-09-26</p> <p>Many volcanic hazard factors--such as the likelihood and duration of an eruption, the eruption style, and the probability of its triggering large landslides or caldera collapses--relate to the depth of the magma source. Yet, the magma source depths are commonly poorly known, even in frequently erupting volcanoes such as Hekla in Iceland and Etna in Italy. Here we show how the length-thickness ratios of feeder dykes can be used to estimate the depth to the source magma chamber. Using this method, accurately measured volcanic fissures/feeder-dykes in El <span class="hlt">Hierro</span> (Canary Islands) indicate a source depth of 11-15 km, which coincides with the main cloud of earthquake foci surrounding the magma chamber associated with the 2011-2012 eruption of El <span class="hlt">Hierro</span>. The method can be used on widely available GPS and InSAR data to calculate the depths to the source magma chambers of active volcanoes worldwide.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3422089','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3422089"><span>Cervical disc arthroplasty: Pros and <span class="hlt">cons</span></span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Moatz, Bradley; Tortolani, P. Justin</p> <p>2012-01-01</p> <p>Background: Cervical disc arthroplasty has emerged as a promising potential alternative to anterior cervical discectomy and fusion (ACDF) in appropriately selected patients. Despite a history of excellent outcomes after ACDF, the question as to whether a fusion leads to adjacent segment degeneration remains unanswered. Numerous US investigational device exemption trials comparing cervical arthroplasty to fusion have been conducted to answer this question. Methods: This study reviews the current research regarding cervical athroplasty, and emphasizes both the pros and <span class="hlt">cons</span> of arthroplasty as compared with ACDF. Results: Early clinical outcomes show that cervical arthroplasty is as effective as the standard ACDF. However, this new technology is also associated with an expanding list of novel complications. Conclusion: Although there is no definitive evidence that cervical disc replacement reduces the incidence of adjacent segment degeneration, it does show other advantages; for example, faster return to work, and reduced need for postoperative bracing. PMID:22905327</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22905327','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22905327"><span>Cervical disc arthroplasty: Pros and <span class="hlt">cons</span>.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Moatz, Bradley; Tortolani, P Justin</p> <p>2012-01-01</p> <p>Cervical disc arthroplasty has emerged as a promising potential alternative to anterior cervical discectomy and fusion (ACDF) in appropriately selected patients. Despite a history of excellent outcomes after ACDF, the question as to whether a fusion leads to adjacent segment degeneration remains unanswered. Numerous US investigational device exemption trials comparing cervical arthroplasty to fusion have been conducted to answer this question. This study reviews the current research regarding cervical athroplasty, and emphasizes both the pros and <span class="hlt">cons</span> of arthroplasty as compared with ACDF. Early clinical outcomes show that cervical arthroplasty is as effective as the standard ACDF. However, this new technology is also associated with an expanding list of novel complications. Although there is no definitive evidence that cervical disc replacement reduces the incidence of adjacent segment degeneration, it does show other advantages; for example, faster return to work, and reduced need for postoperative bracing.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28398150','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28398150"><span><span class="hlt">Conning</span> the conmen: Intelligence and female desire in Dedh Ishqiya.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Singh, Shailendra Kumar</p> <p>2018-01-02</p> <p>This article investigates the ostensibly paradoxical relationship that exists between the theme of excessive love, as suggested by the title of Abhishek Chaubey's film Dedh Ishqiya (2014), and the actual representation of it in the movie, which is not only restrained and disproportionate, but is also looked at with suspicion and contempt. It examines the logic of this seeming contradiction through the other two related themes that Chaubey's chef-d'œuvre foregrounds, namely that of intelligence and female desire. The quest for financial autonomy that the female protagonists of the movie are involved in-a necessary pre-condition for leading independent lives-is so inextricably intertwined with manipulation, dexterity, and subterfuge, that any overt expression of homoerotic female desire can only jeopardize their existing possibilities of self-aggrandizement. The heteronormative arrangements of Begum Para's palace thus constitute the elaborate mise en scène, behind which female desire is enacted through a politics of intelligence, resourcefulness, discretion, and anonymity. Through this strategic negotiation, which is also a tactical necessity, the female protagonists are not only able to <span class="hlt">con</span> the <span class="hlt">con</span> men in the movie, but also imagine alternative subject positions that recognize the need for both pragmatism and expediency as well as deconstructing heteropatriarchal economies of desire.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/23151232','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/23151232"><span>Pros and <span class="hlt">cons</span> of prognostic disclosure to Japanese cancer patients and their families from the family's point of view.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Yoshida, Saran; Shiozaki, Mariko; Sanjo, Makiko; Morita, Tatsuya; Hirai, Kei; Tsuneto, Satoru; Shima, Yasuo</p> <p>2012-12-01</p> <p>The primary goals of this analysis were to explore the pros and <span class="hlt">cons</span> of prognostic disclosure to patients and their families from the bereaved family's point of view. Semistructured interviews were conducted with 60 bereaved family members of patients with cancer in Japan. There were eight categories of influence related to the disclosure of prognosis to the family, including pros (e.g., "Enabling mental preparedness for the patient's death") and <span class="hlt">cons</span> (e.g., "Being distressed by acknowledging the patient's prognosis"); and seven categories of influence of not disclosing the prognosis to family, including pros (e.g., "Being able to maintain hope") and <span class="hlt">cons</span> (e.g., "Being prevented from providing adequate care for the patient"). There were also nine categories of influence related to the disclosure of prognosis to patients (e.g., "Enabling various discussions regarding death with the patient"), and eight categories of influence related to not disclosing the prognosis to patients (e.g., "Maintaining the patient's hope"). Although prognostic disclosure to family members can contribute to psychological distress and hopelessness, at the same time, it has the potential to prepare them for the future both emotionally and practically, and also to make the time until the patient's death as meaningful as possible. It is useful for physicians to introduce pros and <span class="hlt">cons</span> of prognostic disclosure to family members at the time of decision making, to understand the family members' psychological state, and to provide support considering pros and <span class="hlt">cons</span> whether or not they disclosed prognosis.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/6479930','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/6479930"><span>Public mental hospital work: pros and <span class="hlt">cons</span> for psychiatrists.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Miller, R D</p> <p>1984-09-01</p> <p>The extensive literature concerning public mental hospitals has largely been written from the perspective of administrators and systems analysts; most of the reports emphasize the frustrations and problems of working in public mental hospitals and the continued exodus of psychiatrists from these facilities. The author addresses the pros and <span class="hlt">cons</span> of such a career choice from the viewpoint of one who has been an "Indian" rather than a "chief" for a decade. He suggests that the current financial situation in both private practice and academia makes work in public mental hospitals increasingly attractive.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://eric.ed.gov/?q=alicia&id=EJ1102652','ERIC'); return false;" href="https://eric.ed.gov/?q=alicia&id=EJ1102652"><span>Silence, Metaperformance, and Communication in Pedro Almodóvar's "Hable <span class="hlt">con</span> ella"</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Fellie, Maria C.</p> <p>2016-01-01</p> <p>Many scenes in Pedro Almodóvar's "Hable <span class="hlt">con</span> ella" (2002) include shots of metaperformances such as silent films, dances, television shows, concerts, and bullfights. Spectators often observe passive characters who are in turn observing. By presenting these performances within cinematic performance, Almodóvar highlights our role as viewers…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/20180002187','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/20180002187"><span>U.S. Exploration EVA: <span class="hlt">Con</span>Ops, Interfaces and Test Objectives for Airlocks</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Buffington, J.</p> <p>2017-01-01</p> <p>NASA is moving forward on defining the xEVA System Architecture and its implications to the spacecraft that host exploration EVA systems. This presentation provides an overview of the latest information for NASA's Concept of Operations (<span class="hlt">Con</span>Ops), Interfaces and corresponding Test Objectives for Airlocks hosting the xEVA System.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27621201','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27621201"><span>Evaluation of <span class="hlt">Con</span>Prim: A three-part model for continuing education in primary health care.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Berggren, Erika; Strang, Peter; Orrevall, Ylva; Ödlund Olin, Ann; Sandelowsky, Hanna; Törnkvist, Lena</p> <p>2016-11-01</p> <p>To overcome the gap between existing knowledge and the application of this knowledge in practice, a three-part continuing educational model for primary health care professionals (<span class="hlt">Con</span>Prim) was developed. It includes a web-based program, a practical exercise and a case seminar. To evaluate professionals' perceptions of the design, pedagogy and adaptation to primary health care of the <span class="hlt">Con</span>Prim continuing educational model as applied in a subject-specific intervention. A total of 67 professionals (nurses and physicians) completed a computer-based questionnaire evaluating the model's design, pedagogy and adaptation to primary health care one week after the intervention. Descriptive statistics were used. Over 90% found the design of the web-based program and case seminar attractive; 86% found the design of the practical exercise attractive. The professionals agreed that the time spent on two of the three parts was acceptable. The exception was the practical exercise: 32% did not fully agree. Approximately 90% agreed that the contents of all parts were relevant to their work and promoted interactive and interprofessional learning. In response to the statements about the intervention as whole, approximately 90% agreed that the intervention was suitable to primary health care, that it had increased their competence in the subject area, and that they would be able to use what they had learned in their work. <span class="hlt">Con</span>Prim is a promising model for continuing educational interventions in primary health care. However, the time spent on the practical exercise should be adjusted and the instructions for the exercise clarified. <span class="hlt">Con</span>Prim should be tested in other subject-specific interventions and its influence on clinical practice should be evaluated. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://eric.ed.gov/?q=logo+AND+recognition&pg=2&id=ED218687','ERIC'); return false;" href="https://eric.ed.gov/?q=logo+AND+recognition&pg=2&id=ED218687"><span>Advocacy in the Public Forum: The Pro/<span class="hlt">Con</span> Program at Ohio State.</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Stegman, John D.</p> <p></p> <p>The Pro/<span class="hlt">Con</span> Campus Debate and Community Forum program at The Ohio State University serves the educational mission of the department of communication and contributes to the intellectual life of the student body and the larger community by emphasizing the needs of the audience. Eschewing jargon and rhetorical tricks, the program encourages the…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27796180','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27796180"><span>Evaluation of a new automated microscopy urine sediment analyser - sediMAX <span class="hlt">con</span>TRUST®.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Bogaert, Laura; Peeters, Bart; Billen, Jaak</p> <p>2017-04-01</p> <p>This study evaluated the performance of the stand-alone sediMAX <span class="hlt">con</span>TRUST (77Elektronika, Budapest, Hungary) analyser as an alternative to microscopic analysis of urine. The validation included a precision, carry-over, categorical correlation and diagnostic performance study with manual phase-contrast microscopy as reference method. A total of 260 routine urine samples were assessed. The within-run precision was much better at higher concentrations than at very low concentrations. The precision met our predefined limits for all the elements at the different concentrations, with the exception of the lowest RBC, the WBC, pathological casts and crystals count. There was no sample carry-over. The analyser showed good categorical agreement with manual microscopy for RBC and WBC counts, moderate agreement for yeast cells, crystals and squamous epithelial cells and bad agreement for non-squamous epithelial cells, bacteria and casts. Diagnostic performance was satisfying only for RBC, WBC and yeast cells. The number of false negative results was acceptable (≤4%) for all elements after connecting the sediMAX <span class="hlt">con</span>TRUST with an automatic strip reader (AutionMAX) and after implementation of review rules. We conclude that the sediMAX <span class="hlt">con</span>TRUST should be used as a screening tool in combination with an automatic strip reader, for the identification of normal samples. Therefore, adequate review rules should be defined. Manual microscopy is still required in 'flagged' pathological samples. Despite the poor analytical performance on pathological samples, the images on the screen can be used for interpretation without the microscope and can be stored as PDF-documents for archiving the results.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_10");'>10</a></li> <li><a href="#" onclick='return showDiv("page_11");'>11</a></li> <li class="active"><span>12</span></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_12 --> <div id="page_13" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_11");'>11</a></li> <li><a href="#" onclick='return showDiv("page_12");'>12</a></li> <li class="active"><span>13</span></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="241"> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA550476','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA550476"><span>Acoustic Detection, Behavior, and Habitat Use of Deep-Diving Odontocetes</span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>2011-09-22</p> <p>de Estudios de Biologia Marina. Alicante. Spain, Sept. 2010. Escanez A., Guerra A., Gonzalez A., Landeira J., Vicente A., Arranz P., Aguilar N...34Cefalopodos mesopelagicos capturados en las islas de El <span class="hlt">Hierro</span> u Tenerife durante la campana Zifiocal-I", Sociedad Iberico de Estudios de Biologia</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA542167','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA542167"><span>Acoustic Detection, Behavior, and Habitat Use of Deep-Diving Odontocetes</span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>2010-09-30</p> <p>Biologia Marina, Alicante, Sept. 2010. Escanez A., Guerra A., Gonzalez A., Landeira J., Vicente A., Arranz P., Aguilar N., "Cefalopodos...mesopelagicos capturados en las islas de El <span class="hlt">Hierro</span> u Tenerife durante la campana Zifiocal-I", Sociedad Iberico de Estudios de Biologia Marina, Alicante, Sept</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29722915','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29722915"><span>The global regulator of pathogenesis Pn<span class="hlt">Con</span>7 positively regulates Tox3 effector gene expression through direct interaction in the wheat pathogen Parastagonospora nodorum.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Lin, Shao-Yu; Chooi, Yit-Heng; Solomon, Peter S</p> <p>2018-05-03</p> <p>To investigate effector gene regulation in the wheat pathogenic fungus Parastagonospora nodorum, the promoter and expression of Tox3 was characterised through a series of complementary approaches. Promoter deletion and DNase I footprinting experiments identified a 25 bp region in the Tox3 promoter as being required for transcription. Subsequent yeast one-hybrid analysis using the DNA sequence as bait identified that interacting partner as the C2H2 zinc finger transcription factor Pn<span class="hlt">Con</span>7, a putative master regulator of pathogenesis. Silencing of Pn<span class="hlt">Con</span>7 resulted in the down-regulation of Tox3 demonstrating that the transcription factor has a positive regulatory role on gene expression. Analysis of Tox3 expression in the Pn<span class="hlt">Con</span>7 silenced strains revealed a strong correlation with Pn<span class="hlt">Con</span>7 transcript levels, supportive of a direct regulatory role. Subsequent pathogenicity assays using Pn<span class="hlt">Con</span>7-silenced isolates revealed that the transcription factor was required for Tox3-mediated disease. The expression of two other necrotrophic effectors (ToxA and Tox1) was also affected but in a non-dose dependent manner suggesting that the regulatory role of Pn<span class="hlt">Con</span>7 on these genes was indirect. Collectively, these data have advanced our fundamental understanding of the <span class="hlt">Con</span>7 master regulator of pathogenesis by demonstrating its positive regulatory role on the Tox3 effector in P. nodorum through direct interaction. This article is protected by copyright. All rights reserved. © 2018 John Wiley & Sons Ltd.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2003EAEJA......778V','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2003EAEJA......778V"><span>Pro/<span class="hlt">con</span> a precessional geodynamo</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Vanyo, J.</p> <p>2003-04-01</p> <p>The modest amount of research that exists on the ability, or lack of ability, of mantle precession to power a geodynamo developed mostly during the last half of the 1900s. Papers by Roberts and Stewartson (1965) and by Busse (1968) studied precession generally without a pro/<span class="hlt">con</span> conclusion. Malkus in the late 1960s attempted to advance a positive role for precession through experiments and analysis. His experiments have survived criticism, but his analyses were discounted, especially by Rochester, Jacobs, Smylie, and Chong (1975) and by Loper (1975). Rochester, et al. critiqued existing analyses of precession, including those of Malkus, but did not reach a strong position either pro or <span class="hlt">con</span> a precessional geodynamo. Loper argued emphatically that precession was not capable of powering the geodynamo. Explicit analyses that either critique or support Loper’s arguments have yet to appear in the literature. During the 1970s, Vanyo and associates studied energy dissipation during precession of satellite liquid fuels and its effect on satellite attitude stability. Engineers and scientists in every country that has launched satellites completed similar research. Some is published in the aerospace literature, more is available in company and government reports. Beginning in 1981, Vanyo and associates applied this knowledge to the very similar problem of energy dissipation and flow patterns in precessing mechanical models scaled geometrically and dynamically to the Earth’s liquid core. Energy experiments indicate massive amounts of mechanical energy are dissipated at the CMB, and flow experiments show complex motions within the boundary layer and axial flows with helicity throughout the interior. Analysis of Earth core precession also advanced, especially in several papers by Kerswell and by Tilgner in the late 1990s. Detail numerical models have yet to appear. Although progress in understanding the role of precession in Earth core motions has advanced, there remains a</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3783892','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3783892"><span>Depth of origin of magma in eruptions</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Becerril, Laura; Galindo, Ines; Gudmundsson, Agust; Morales, Jose Maria</p> <p>2013-01-01</p> <p>Many volcanic hazard factors - such as the likelihood and duration of an eruption, the eruption style, and the probability of its triggering large landslides or caldera collapses - relate to the depth of the magma source. Yet, the magma source depths are commonly poorly known, even in frequently erupting volcanoes such as Hekla in Iceland and Etna in Italy. Here we show how the length-thickness ratios of feeder dykes can be used to estimate the depth to the source magma chamber. Using this method, accurately measured volcanic fissures/feeder-dykes in El <span class="hlt">Hierro</span> (Canary Islands) indicate a source depth of 11–15 km, which coincides with the main cloud of earthquake foci surrounding the magma chamber associated with the 2011–2012 eruption of El <span class="hlt">Hierro</span>. The method can be used on widely available GPS and InSAR data to calculate the depths to the source magma chambers of active volcanoes worldwide. PMID:24067336</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2013PhDT.........9I','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2013PhDT.........9I"><span>Modelo de accesibilidad de conceptos matematicos aplicados en el curso de Astronomia Descriptiva para estudiantes <span class="hlt">con</span> impedimentos visuales en la UPR</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Isidro Villamizar, Gloria Maria</p> <p></p> <p>Este estudio utiliza metodologia de investigacion cualitativa, <span class="hlt">con</span> el proposito de describir, analizar y evaluar los procesos de diseno y desarrollo de un modelo de accesibilidad que consiste en estrategias de ensenanza de las matematicas para estudiantes <span class="hlt">con</span> impedimentos visuales matriculados en el curso de Astronomia Descriptiva en la UPR. Se utilizaron las siguientes estrategias para recopilar la informacion, 1) reflexiones de la investigadora en el proceso de diseno y desarrollo de las lecciones adaptadas, que se registraron en un diario reflexivo. 2) entrevista semiestructurada luego de haber trabajado las lecciones de aprendizaje adaptadas <span class="hlt">con</span> los participantes. 3) observaciones y notas de la investigadora del trabajo de los participantes. Para obtener la informacion de los participantes se obtuvo los permisos institucionales necesarios; se seleccionaron los participantes y se validaron los instrumentos; se realizo el desarrollo de las lecciones adaptadas <span class="hlt">con</span> los participantes; y finalmente, se analizo la informacion obtenida. El diseno de las lecciones de aprendizaje adaptadas se hizo siguiendo las recomendaciones curriculares de los temas de matematicas aplicados en el curso de Astronomia Descriptiva realizado por la investigadora durante su semestre de internado. El testimonio de las voces de los participantes se obtuvo del proceso de desarrollo de las lecciones de aprendizaje adaptadas de temas seleccionados de conceptos matematicos requeridos en el curso de Astronomia Descriptiva y de la entrevista semiestructurada <span class="hlt">con</span> los participantes, luego de haber trabajado las lecciones de aprendizaje. Para el desarrollo de las lecciones de aprendizaje, se utilizaron materiales tactiles adaptados, materiales tactiles disenados y materiales disponibles comercialmente. Los textos de las lecciones se imprimieron en tinta y en Braille. Se exhorta a disenar y desarrollar estrategias de ensenanza accesibles, considerando como recursos para evaluar su efectividad a</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/biblio/22351318-accurate-macromolecular-crystallographic-refinement-incorporation-linear-scaling-semiempirical-quantum-mechanics-program-divcon-phenix-refinement-package','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/22351318-accurate-macromolecular-crystallographic-refinement-incorporation-linear-scaling-semiempirical-quantum-mechanics-program-divcon-phenix-refinement-package"><span>Accurate macromolecular crystallographic refinement: incorporation of the linear scaling, semiempirical quantum-mechanics program Div<span class="hlt">Con</span> into the PHENIX refinement package</span></a></p> <p><a target="_blank" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a></p> <p>Borbulevych, Oleg Y.; Plumley, Joshua A.; Martin, Roger I.</p> <p>2014-05-01</p> <p>Semiempirical quantum-chemical X-ray macromolecular refinement using the program Div<span class="hlt">Con</span> integrated with PHENIX is described. Macromolecular crystallographic refinement relies on sometimes dubious stereochemical restraints and rudimentary energy functionals to ensure the correct geometry of the model of the macromolecule and any covalently bound ligand(s). The ligand stereochemical restraint file (CIF) requires a priori understanding of the ligand geometry within the active site, and creation of the CIF is often an error-prone process owing to the great variety of potential ligand chemistry and structure. Stereochemical restraints have been replaced with more robust functionals through the integration of the linear-scaling, semiempirical quantum-mechanics (SE-QM)more » program Div<span class="hlt">Con</span> with the PHENIX X-ray refinement engine. The PHENIX/Div<span class="hlt">Con</span> package has been thoroughly validated on a population of 50 protein–ligand Protein Data Bank (PDB) structures with a range of resolutions and chemistry. The PDB structures used for the validation were originally refined utilizing various refinement packages and were published within the past five years. PHENIX/Div<span class="hlt">Con</span> does not utilize CIF(s), link restraints and other parameters for refinement and hence it does not make as many a priori assumptions about the model. Across the entire population, the method results in reasonable ligand geometries and low ligand strains, even when the original refinement exhibited difficulties, indicating that PHENIX/Div<span class="hlt">Con</span> is applicable to both single-structure and high-throughput crystallography.« less</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4495745','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4495745"><span>Topical Oxygen for Chronic Wounds: A PRO/<span class="hlt">CON</span> Debate</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Mutluoglu, Mesut; Cakkalkurt, Aslican; Uzun, Gunalp; Aktas, Samil</p> <p>2014-01-01</p> <p>The role of oxygen in wound healing is universally accepted and does not require any further evidence; however the controversy as to whether oxygen delivery systems have the potential to improve wound healing remains to be concluded. Topical oxygen treatment (TOT) involves the delivery of 100% oxygen for a mean of 90 min, once a day at an atmospheric pressure slightly above 1 atm abs. The use of TOT gained increasing interest recently. The current manuscript will summarize the pros and <span class="hlt">cons</span> of TOT in the view of the available literature. PMID:26199891</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://cfpub.epa.gov/si/si_public_record_report.cfm?dirEntryId=234845&Lab=NERL&keyword=health+AND+physics&actType=&TIMSType=+&TIMSSubTypeID=&DEID=&epaNumber=&ntisID=&archiveStatus=Both&ombCat=Any&dateBeginCreated=&dateEndCreated=&dateBeginPublishedPresented=&dateEndPublishedPresented=&dateBeginUpdated=&dateEndUpdated=&dateBeginCompleted=&dateEndCompleted=&personID=&role=Any&journalID=&publisherID=&sortBy=revisionDate&count=50','EPA-EIMS'); return false;" href="https://cfpub.epa.gov/si/si_public_record_report.cfm?dirEntryId=234845&Lab=NERL&keyword=health+AND+physics&actType=&TIMSType=+&TIMSSubTypeID=&DEID=&epaNumber=&ntisID=&archiveStatus=Both&ombCat=Any&dateBeginCreated=&dateEndCreated=&dateBeginPublishedPresented=&dateEndPublishedPresented=&dateBeginUpdated=&dateEndUpdated=&dateBeginCompleted=&dateEndCompleted=&personID=&role=Any&journalID=&publisherID=&sortBy=revisionDate&count=50"><span>Non Invasive Biomedical Analysis - Breath Networking Session at Pitt<span class="hlt">Con</span> 2011, Atlanta, Georgia</span></a></p> <p><a target="_blank" href="http://oaspub.epa.gov/eims/query.page">EPA Science Inventory</a></p> <p></p> <p></p> <p>This was the second year that our breath colleagues organized a networking session at the Pittsburgh Conference and Exposition or ''Pitt<span class="hlt">Con</span>'' (http://www.pincon.org/).This time it was called "Non-invasive Biomedical Analysis" to broaden the scope a bit, but the primary focus rema...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016APS..MARP48005A','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016APS..MARP48005A"><span>Gradient Optimization for Analytic <span class="hlt">con</span>Trols - GOAT</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Assémat, Elie; Machnes, Shai; Tannor, David; Wilhelm-Mauch, Frank</p> <p></p> <p>Quantum optimal control becomes a necessary step in a number of studies in the quantum realm. Recent experimental advances showed that superconducting qubits can be controlled with an impressive accuracy. However, most of the standard optimal control algorithms are not designed to manage such high accuracy. To tackle this issue, a novel quantum optimal control algorithm have been introduced: the Gradient Optimization for Analytic <span class="hlt">con</span>Trols (GOAT). It avoids the piecewise constant approximation of the control pulse used by standard algorithms. This allows an efficient implementation of very high accuracy optimization. It also includes a novel method to compute the gradient that provides many advantages, e.g. the absence of backpropagation or the natural route to optimize the robustness of the control pulses. This talk will present the GOAT algorithm and a few applications to transmons systems.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1998BAAA...42...14M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1998BAAA...42...14M"><span>Segundo Catálogo Estelar del Hemisferio Sur <span class="hlt">con</span> Astrolabio Fotoeléctrico PAII</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Manrique, W. T.; Podestá, R. C.; Alonso, E.; Actis, E. V.; Pacheco, A. M.; Bustos, G.; Lizhi, L.; Zezhi, W.; Fanmiao, Z.; Hongqi, W.; Perdomo, R.</p> <p></p> <p>Recordamos que entre el Observatorio Astronómico ``Félix Aguilar'', el Observatorio Astronómico de Beijing y el Observatorio Astronómico de La Plata, se ha convenido en desarrollar un Proyecto de Investigación conjunto, para la observación sistemática de estrellas en el Hemisferio Sur, <span class="hlt">con</span> el objeto de la elaboración de un Catálogo Estelar Global utilizando un Astrolabio Fotoeléctrico PAII del Observatorio de Beijing, que ha sido usado <span class="hlt">con</span> éxito en la República de China. En este trabajo se presenta el Segundo Catálogo Estelar del Hemisferio Sur, derivado de las observaciones realizadas <span class="hlt">con</span> el PAII instalado en el OAFA, durante el períiodo Febrero de 1992 a Marzo de 1997. En este lapso se han observado mas de 400000 pasajes estelares, obteniéndose las correcciones Δ α y Δ δ de 5241 estrellas del FK4, FK5, FK5 Ext., SRS, CAMC y GC. Las precisiones medias son del orden de ± 3,2 ms en ascensión recta y ±0."057 en declinación. Rango de magnitudes : 2,0 a 11,5 Rango de declinaciones : -3o a -60o Epoca Media : 1994.9 Se analizan los residuos en función de la magnitud y tipo espectral, correcciones de grupo y frecuencia de distribución Δ α y Δ δ.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.fs.usda.gov/treesearch/pubs/21999','TREESEARCH'); return false;" href="https://www.fs.usda.gov/treesearch/pubs/21999"><span>Wilderness for science: pros and <span class="hlt">cons</span> of using wilderness areas for biological research</span></a></p> <p><a target="_blank" href="http://www.fs.usda.gov/treesearch/">Treesearch</a></p> <p>Diana L. Six; Paul Alaback; Robert A. Winfree; Delia Snyder; Anne Hagele</p> <p>2000-01-01</p> <p>Research is one of the intended purposes of wilderness. The Wilderness Act states that “wilderness may contain ecological, geological, or other features of scientific, educational, scenic, or historical value.” This session specifically focuses on the pros and <span class="hlt">cons</span> of conducting research in wilderness.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/12001231','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/12001231"><span><span class="hlt">Cons</span>Dock: A new program for the consensus analysis of protein-ligand interactions.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Paul, Nicodème; Rognan, Didier</p> <p>2002-06-01</p> <p>Protein-based virtual screening of chemical libraries is a powerful technique for identifying new molecules that may interact with a macromolecular target of interest. Because of docking and scoring limitations, it is more difficult to apply as a lead optimization method because it requires that the docking/scoring tool is able to propose as few solutions as possible and all of them with a very good accuracy for both the protein-bound orientation and the conformation of the ligand. In the present study, we present a consensus docking approach (<span class="hlt">Cons</span>Dock) that takes advantage of three widely used docking tools (Dock, FlexX, and Gold). The consensus analysis of all possible poses generated by several docking tools is performed sequentially in four steps: (i) hierarchical clustering of all poses generated by a docking tool into families represented by a leader; (ii) definition of all consensus pairs from leaders generated by different docking programs; (iii) clustering of consensus pairs into classes, represented by a mean structure; and (iv) ranking the different means starting from the most populated class of consensus pairs. When applied to a test set of 100 protein-ligand complexes from the Protein Data Bank, <span class="hlt">Cons</span>Dock significantly outperforms single docking with respect to the docking accuracy of the top-ranked pose. In 60% of the cases investigated here, <span class="hlt">Cons</span>Dock was able to rank as top solution a pose within 2 A RMSD of the X-ray structure. It can be applied as a postprocessing filter to either single- or multiple-docking programs to prioritize three-dimensional guided lead optimization from the most likely docking solution. Copyright 2002 Wiley-Liss, Inc.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/biblio/1353316-change-brooklyn-queens-how-new-york-reforming-energy-vision-program-con-edison-reshaping-electric-distribution-planning','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/1353316-change-brooklyn-queens-how-new-york-reforming-energy-vision-program-con-edison-reshaping-electric-distribution-planning"><span>Change in Brooklyn and Queens: How New York?s Reforming the Energy Vision Program and <span class="hlt">Con</span> Edison Are Reshaping Electric Distribution Planning</span></a></p> <p><a target="_blank" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a></p> <p>Coddington, Michael; Sciano, Damian; Fuller, Jason</p> <p></p> <p>In response to this tremendous growth in both population and electricity demand, <span class="hlt">Con</span> Edison estimates that its cost to expand the “traditional” Brooklyn-Queens grid will be in the neighborhood of US$1.2 billion—a relatively high number, even for New York City and <span class="hlt">Con</span> Edison. The complexity of the city’s underground electrical system along with the difficulties of construction in a highly congested urban environment with infrastructure both above and below ground mean that the costs for transmission, substations, and secondary networks are significantly higher than those of a typical electric utility. The New York State Public Service Commission (PSC) is inmore » the process revising its approach to acquiring and serving energy throughout the state of New York, and traditional expansion for this rather costly project was not likely to be approved. Instead, the PSC asked <span class="hlt">Con</span> Edison to evaluate numerous alternatives. The PSC and <span class="hlt">Con</span> Edison are now considering and adopting strategies that include renewable energy generation, demand response (DR), battery energy storage systems, fuel-cell distributed generation, combined heat and power, volt-volt ampere reactive (VAR) optimization (VVO), and a host of other innovative solutions that would both reduce electricity demand and transform how and when <span class="hlt">Con</span> Edison’s consumers use electricity.« less</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/biblio/425732-neogene-sequence-stratigraphy-nam-con-son-basin-offshore-vietnam','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/425732-neogene-sequence-stratigraphy-nam-con-son-basin-offshore-vietnam"><span>Neogene sequence stratigraphy, Nam <span class="hlt">Con</span> Son Basin, offshore Vietnam</span></a></p> <p><a target="_blank" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a></p> <p>McMillen, K.J.; Do Van Luu; Lee, E.K.</p> <p>1996-12-31</p> <p>An integrated well log, biostratigraphic, and seismic stratigraphic study of Miocene to Recent deltaic sediments deposited in the Nam <span class="hlt">Con</span> Son Basin offshore from southern Vietnam shows the influence of eustacy and tectonics on sequence development. Sediments consist of Oligocene non-marine rift-basin fill (Cau Formation), early to middle Miocene tide-dominated delta plain to delta front sediments (TB 1.5 to TB 2.5, Due and Thong Formations), and late Miocene to Recent marine shelf sediments (TB. 2.6 to TB 3.1 0, Mang Cau, Nam <span class="hlt">Con</span> Son, and Bien Dong Formations). Eustacy controlled the timing of key surfaces and sand distribution in themore » tectonically-quiet early Miocene. Tectonic effects on middle to late Miocene sequence development consist of thick transgressive systems tracts due to basin-wide subsidence and transgression, sand distribution in the basin center, and carbonate sedimentation on isolated fault blocks within the basin. Third-order sequence boundaries (SB) are identified by spore peaks, sand stacking patterns, and channel incision. In the basin center, widespread shale beds with coal occur above sequence boundaries followed by transgressive sandstone units. These TST sandstones merge toward the basin margin where they lie on older HST sandstones. Maximum flooding surfaces (MFS) have abundant marine microfossils and mangrove pollen, a change in sand stacking pattern, and often a strong seismic reflection with downlap. Fourth-order genetic-type sequences are also interpreted. The MFS is the easiest marker to identify and correlate on well logs. Fourth-order SB occur within these genetic units but are harder to identify and correlate.« less</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/biblio/6595465-neogene-sequence-stratigraphy-nam-con-son-basin-offshore-vietnam','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/6595465-neogene-sequence-stratigraphy-nam-con-son-basin-offshore-vietnam"><span>Neogene sequence stratigraphy, Nam <span class="hlt">Con</span> Son Basin, offshore Vietnam</span></a></p> <p><a target="_blank" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a></p> <p>McMillen, K.J.; Do Van Luu; Lee, E.K.</p> <p>1996-01-01</p> <p>An integrated well log, biostratigraphic, and seismic stratigraphic study of Miocene to Recent deltaic sediments deposited in the Nam <span class="hlt">Con</span> Son Basin offshore from southern Vietnam shows the influence of eustacy and tectonics on sequence development. Sediments consist of Oligocene non-marine rift-basin fill (Cau Formation), early to middle Miocene tide-dominated delta plain to delta front sediments (TB 1.5 to TB 2.5, Due and Thong Formations), and late Miocene to Recent marine shelf sediments (TB. 2.6 to TB 3.1 0, Mang Cau, Nam <span class="hlt">Con</span> Son, and Bien Dong Formations). Eustacy controlled the timing of key surfaces and sand distribution in themore » tectonically-quiet early Miocene. Tectonic effects on middle to late Miocene sequence development consist of thick transgressive systems tracts due to basin-wide subsidence and transgression, sand distribution in the basin center, and carbonate sedimentation on isolated fault blocks within the basin. Third-order sequence boundaries (SB) are identified by spore peaks, sand stacking patterns, and channel incision. In the basin center, widespread shale beds with coal occur above sequence boundaries followed by transgressive sandstone units. These TST sandstones merge toward the basin margin where they lie on older HST sandstones. Maximum flooding surfaces (MFS) have abundant marine microfossils and mangrove pollen, a change in sand stacking pattern, and often a strong seismic reflection with downlap. Fourth-order genetic-type sequences are also interpreted. The MFS is the easiest marker to identify and correlate on well logs. Fourth-order SB occur within these genetic units but are harder to identify and correlate.« less</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://eric.ed.gov/?q=pros+AND+cons+AND+technology&pg=5&id=EJ717645','ERIC'); return false;" href="https://eric.ed.gov/?q=pros+AND+cons+AND+technology&pg=5&id=EJ717645"><span>Are You Ready to Go Digital?: The Pros and <span class="hlt">Cons</span> of Electronic Portfolio Development</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Heath, Marilyn</p> <p>2005-01-01</p> <p>There is an increasing need for educators to have professional portfolios, which are considered to be authentic tools for evaluating the knowledge, skill, beliefs and attitudes of prospective educators. Electronic portfolios are gaining in popularity and their relative pros and <span class="hlt">cons</span> are examined.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4686126','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4686126"><span>RETOS EN LA INTERVENCIÓN <span class="hlt">CON</span> ADOLESCENTES PUERTORRIQUEÑOS/AS QUE MANIFIESTAN COMPORTAMIENTO SUICIDA*</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Vélez, Yovanska Duarté; Dávila, Paloma Torres; Hernández, Samariz Laboy</p> <p>2015-01-01</p> <p>Presentamos un estudio de caso de una adolescente puertorriqueña <span class="hlt">con</span> comportamiento suicida. Esta comenzó una Terapia Socio Cognitivo-Conductual para el Comportamiento Suicida (TSCC-CS) de tipo ambulatorio luego de una hospitalización por intento suicida. La TSCC-CS incorpora una perspectiva ecológica y de desarrollo a la terapia cognitivo-conductual. Inicialmente mostró baja autoestima y severos síntomas depresivos y de ansiedad. Al finalizar el tratamiento, manifestó un cambio significativo en su sintomatología clínica y evidenció una mejoría en sus destrezas de manejo. No presentó ideas suicidas durante meses previos, ni durante el seguimiento. El análisis de este caso permitió realizar cambios en el protocolo de tratamiento, particularmente en las sesiones de familia y de comunicación <span class="hlt">con</span> el fin de aumentar la viabilidad del tratamiento. PMID:26702337</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/23906891','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/23906891"><span>Use of a GnRH vaccine, Gona<span class="hlt">Con</span>, for prevention and treatment of adrenocortical disease (ACD) in domestic ferrets.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Miller, Lowell A; Fagerstone, Kathleen A; Wagner, Robert A; Finkler, Mark</p> <p>2013-09-23</p> <p>Adrenocortical disease (ACD) is a common problem in surgically sterilized, middle-aged to old ferrets (Mustela putorius furo). The adrenal tissues of these ferrets develop hyperplasia, adenomas, or adenocarcinomas, which produce steroid hormones including estradiol, 17-hydroxyprogesterone, and androstenedione. Major clinical signs attributable to overproduction of these hormones are alopecia (hair loss) in both sexes and a swollen vulva in females. Pruritus, muscle atrophy, hind limb weakness, and sexual activity or aggression are also observed in both sexes. Males can develop prostatic cysts, prostatitis, and urethral obstruction. ACD is thought to be linked to continuous and increased LH secretion, due to lack of gonadal hormone feedback in neutered ferrets. This continuous elevated LH acts on adrenal cortex LH receptors, resulting in adrenal hyperplasia or adrenal tumor. This study investigated whether the immunocontraceptive vaccine Gona<span class="hlt">Con</span>, a GnRH vaccine developed to reduce the fertility of wildlife species and the spread of disease, could prevent or delay onset of ACD and treat alopecia in ferrets with existing ACD. Results showed that Gona<span class="hlt">Con</span> provided relief from ACD by causing production of antibodies to GnRH, probably suppressing production and/or release of LH. Treatment caused many ACD symptoms to disappear, allowing the ferrets to return to a normal life. The study also found that the probability of developing ACD was significantly reduced in ferrets treated with Gona<span class="hlt">Con</span> when young (1-3 years old) compared to untreated control animals. Gona<span class="hlt">Con</span> caused injection site reaction in some animals when administered as an intramuscular injection but caused few side effects when administered subcutaneously. Both intramuscular and subcutaneous vaccination resulted in similar levels of GnRH antibody titers. Subcutaneous vaccination with Gona<span class="hlt">Con</span> is thus recommended to prevent the onset of ACD and as a possible treatment for ACD-signs in domestic ferrets. Published</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/21088107','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/21088107"><span>Anabaena sp. strain PCC 7120 <span class="hlt">con</span>R contains a LytR-CpsA-Psr domain, is developmentally regulated, and is essential for diazotrophic growth and heterocyst morphogenesis.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Mella-Herrera, Rodrigo A; Neunuebel, M Ramona; Golden, James W</p> <p>2011-03-01</p> <p>The <span class="hlt">con</span>R (all0187) gene of the filamentous cyanobacterium Anabaena (Nostoc) sp. strain PCC 7120 is predicted to be part of a family of proteins that contain the LytR-CpsA-Psr domain associated with septum formation and cell wall maintenance. The <span class="hlt">con</span>R gene was originally misannotated as a transcription regulator. Northern RNA blot analysis showed that <span class="hlt">con</span>R expression was upregulated 8 h after nitrogen step-down. Fluorescence microscopy of a P(<span class="hlt">con</span>R)-gfp reporter strain revealed increased GFP fluorescence in proheterocysts and heterocysts beginning 9 h after nitrogen step-down. Insertional inactivation of <span class="hlt">con</span>R caused a septum-formation defect of vegetative cells grown in nitrate-containing medium. In nitrate-free medium, mutant filaments formed abnormally long heterocysts and were defective for diazotrophic growth. Septum formation between heterocysts and adjacent vegetative cells was abnormal, often with one or both poles of the heterocysts appearing partially open. In a <span class="hlt">con</span>R mutant, expression of nifH was delayed after nitrogen step-down and nitrogenase activity was approximately 70 % of wild-type activity, indicating that heterocysts of the <span class="hlt">con</span>R mutant strain are partially functional. We hypothesize that the diazotrophic growth defect is caused by an inability of the heterocysts to transport fixed nitrogen to the neighbouring vegetative cells.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_11");'>11</a></li> <li><a href="#" onclick='return showDiv("page_12");'>12</a></li> <li class="active"><span>13</span></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_13 --> <div id="page_14" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_12");'>12</a></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li class="active"><span>14</span></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="261"> <li> <p><a target="_blank" onclick="trackOutboundLink('https://eric.ed.gov/?q=familia&id=EJ1124407','ERIC'); return false;" href="https://eric.ed.gov/?q=familia&id=EJ1124407"><span>"<span class="hlt">Con</span> todo mi corazón": Mentoring Latinas in Educational Leadership Doctoral Programs</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Rodríguez, Mariela A.</p> <p>2016-01-01</p> <p>Personal narrative essays were used to analyze the experiences of four Latina doctoral students who completed their first year in an educational leadership doctoral program in a Hispanic-Serving Institution (HSI) in the southwestern U.S. Four themes emerged from their "testimonios" 1) "<span class="hlt">Con</span> todo el corazón"; 2) "Somos como…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29874708','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29874708"><span>Contaminación por mercurio de leche materna de madres lactantes de municipios de Antioquia <span class="hlt">con</span> explotación minera de oro.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Molina, Carlos Federico; Arango, Catalina María; Sepúlveda, Hernán</p> <p>2018-05-01</p> <p>Introducción. La leche materna es esencial para el desarrollo del ser humano, pero puede contener sustancias tóxicas provenientes de la contaminación ambiental, especialmente en las áreas mineras.Objetivo. Determinar la prevalencia de la contaminación <span class="hlt">con</span> mercurio de la leche materna de mujeres lactantes residentes en los municipios <span class="hlt">con</span> explotación minera de oro.Materiales y métodos. Se hizo un estudio transversal de 150 madres lactantes de cuatro municipios mineros de Antioquia (El Bagre, Segovia, Remedios y Zaragoza), a quienes se les hizo una encuesta sobre factores sociodemográficos, ocupacionales y ambientales relacionados <span class="hlt">con</span> el mercurio, y se les tomaron muestras de leche materna, de orina y de cabello. Se calculó el promedio de la concentración de mercurio y las prevalencias municipales de contaminación.Resultados. El promedio de la concentración de mercurio en la leche materna fue de 2,5 (± desviación estándar 9,2) μg/L. La prevalencia de muestras de leche materna <span class="hlt">con</span> niveles altos de mercurio fue de 11,7 %.Conclusión. En este estudio se evidencia un grave problema en las regiones mineras auríferas de Antioquia por el efecto de la contaminación <span class="hlt">con</span> mercurio en sectores de la población más vulnerable.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://eric.ed.gov/?q=tax+AND+compliance+AND+cost&id=ED330435','ERIC'); return false;" href="https://eric.ed.gov/?q=tax+AND+compliance+AND+cost&id=ED330435"><span>The <span class="hlt">Con</span> Edison Emergency Child Care Plan for Management Employees: Summary Plan Description.</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Consolidated Edison Co., Brooklyn, NY.</p> <p></p> <p>This summary plan description offers guidelines for participation in a pilot program that provides short-term emergency care for children of <span class="hlt">Con</span> Edison managers who are under 13 years old. The plan offers professional, in-home child care that can be used when usual arrangements have collapsed. The summary plan description addresses the following…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://files.eric.ed.gov/fulltext/EJ1138165.pdf','ERIC'); return false;" href="http://files.eric.ed.gov/fulltext/EJ1138165.pdf"><span>Pros & <span class="hlt">Cons</span> of Using Blackboard Collaborate for Blended Learning on Students' Learning Outcomes</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Hamad, Mona M.</p> <p>2017-01-01</p> <p>Blackboard Collaborate was introduced to King Khalid University recently in the last decade; instructors and students were trained to use it in an effective way. The objective of this study is to find pros and <span class="hlt">cons</span> of using Blackboard Collaborate for Blended Learning and its effect on students' learning outcomes. The researcher used the…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4623611','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4623611"><span>Aspergilosis cervical <span class="hlt">con</span> diseminación al sistema nervioso central. Presentación de un caso y revisión de bibliografía</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Vergara, Guillermo Enrique; Roura, Natalia; del Castillo, Marcelo; Mora, Andrea; Alcorta, Santiago Condomi; Mormandi, Rubén; Cervio, Andrés; Salvat, Jorge</p> <p>2015-01-01</p> <p>Introducción: la Aspergilosis Invasiva (AI) del Sistema Nervioso Central (SNC) es infrecuente y ocurre generalmente en pacientes inmunocomprometidos. Puede presentarse <span class="hlt">con</span> cuadros de meningitis, aneurismas micóticos, infartos o abscesos. Es una infección <span class="hlt">con</span> pronóstico reservado y puede afectar el SNC de forma primaria o secundaria a partir de un foco que se disemina por vía hematógena. Presentamos el caso de un paciente <span class="hlt">con</span> AI <span class="hlt">con</span> invasión primaria a nivel óseo y diseminación posterior al cerebro. Caso clínico: Paciente masculino de 25 años <span class="hlt">con</span> diagnóstico de leucemia linfática aguda en tratamiento quimioterápico que presentó neumonitis por metotrexate por lo que inicia tratamiento <span class="hlt">con</span> corticoides. Posteriormente agregó cervicalgia y <span class="hlt">con</span> el diagnóstico de osteomielitis cervical se realiza punción bajo tomografía computada (TC) sin aislarse gérmenes. Se colocó Halo Vest e inició tratamiento antibiótico empírico. Posteriormente presentó afasia de expresión secundaria a lesión frontal izquierda. Se realizó evacuación de absceso cerebral aislando A. fumigatus. El tratamiento antibiótico específico posterior permitió una buena respuesta clínica y radiológica. Conclusión: La presencia de lesiones en el SNC de pacientes inmunocomprometidos debe incluir a las micosis como diagnóstico diferencial. La evacuación quirúrgica permite llegar rápidamente al diagnóstico mejorando la respuesta posterior al tratamiento antibiótico. Para evaluar la respuesta terapéutica y posibles recaídas se debe realizar un seguimiento periódico clínico radiológico. Palabras clave: Aspergilosis cerebral; Aspergilosis cervical; Aspergilosis invasiva; Voriconazol. PMID:26600985</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/biblio/425555-structure-stratigraphy-petroleum-geology-south-east-nam-con-son-basin-offshore-vietnam','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/425555-structure-stratigraphy-petroleum-geology-south-east-nam-con-son-basin-offshore-vietnam"><span>Structure, stratigraphy and petroleum geology of the south east Nam <span class="hlt">Con</span> Son Basin, offshore Vietnam</span></a></p> <p><a target="_blank" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a></p> <p>Fraser, A.J.; Matthews, S.J.; Lowe, S.</p> <p>1996-12-31</p> <p>Recent exploration of the south east Nam <span class="hlt">Con</span> Son Basin, offshore Vietnam, by BP in alliance with Statoil has involved acquisition of new seismic and well data. These new data have allowed re-evaluation of the tectono-stratigraphic development and petroleum geology, and have provided additional constraints on the regional tectonic evolution. The offshore Vietnamese basins have evolved in response to the complex relative motions of Indochina, Peninsular Malaysia, Borneo and the South China Sea during the Cenozoic. On the regional scale these motions have been accommodated by strike-slip fault development, rifting and contraction. In the Nam <span class="hlt">Con</span> Son Basin these motionsmore » have interacted in different ways from the Palaeogene to recent. Two rifting episodes are recognized; a Palaeogene phase dominated by E-W trending extensional faults, and a Miocene phase dominated by N-S to NE-SW trending faults. The structural evolution is complicated by a pulse of mild contraction during the Middle Miocene. The sedimentary fill of the basin evolves from continental fluvio-lacustrine in the Palaeogene through to fully marine following the second phase of rifting in the Miocene. This pulsed structural and stratigraphic evolution has resulted in basinwide deposition of source, reservoir and seal facies, and produced a variety of potential trapping styles. This paper describes the hydrocarbon habitat of the south east Nam <span class="hlt">Con</span> Son Basin within the context of the regional tectono-stratigraphic model.« less</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/biblio/6592260-structure-stratigraphy-petroleum-geology-south-east-nam-con-son-basin-offshore-vietnam','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/6592260-structure-stratigraphy-petroleum-geology-south-east-nam-con-son-basin-offshore-vietnam"><span>Structure, stratigraphy and petroleum geology of the south east Nam <span class="hlt">Con</span> Son Basin, offshore Vietnam</span></a></p> <p><a target="_blank" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a></p> <p>Fraser, A.J.; Matthews, S.J.; Lowe, S.</p> <p>1996-01-01</p> <p>Recent exploration of the south east Nam <span class="hlt">Con</span> Son Basin, offshore Vietnam, by BP in alliance with Statoil has involved acquisition of new seismic and well data. These new data have allowed re-evaluation of the tectono-stratigraphic development and petroleum geology, and have provided additional constraints on the regional tectonic evolution. The offshore Vietnamese basins have evolved in response to the complex relative motions of Indochina, Peninsular Malaysia, Borneo and the South China Sea during the Cenozoic. On the regional scale these motions have been accommodated by strike-slip fault development, rifting and contraction. In the Nam <span class="hlt">Con</span> Son Basin these motionsmore » have interacted in different ways from the Palaeogene to recent. Two rifting episodes are recognized; a Palaeogene phase dominated by E-W trending extensional faults, and a Miocene phase dominated by N-S to NE-SW trending faults. The structural evolution is complicated by a pulse of mild contraction during the Middle Miocene. The sedimentary fill of the basin evolves from continental fluvio-lacustrine in the Palaeogene through to fully marine following the second phase of rifting in the Miocene. This pulsed structural and stratigraphic evolution has resulted in basinwide deposition of source, reservoir and seal facies, and produced a variety of potential trapping styles. This paper describes the hydrocarbon habitat of the south east Nam <span class="hlt">Con</span> Son Basin within the context of the regional tectono-stratigraphic model.« less</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/20110001377','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/20110001377"><span>NASA KSC/AFRL Reusable Booster System (RBS) Concept of Operations (<span class="hlt">Con</span>Ops)</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Zeno, Dnany; Mosteller, Ted; McCleskey, Carey; Jhnson, Robert; Hopkins, Jason; Miller, Thomas</p> <p>2010-01-01</p> <p>This slide presentation reviews the study and findings of the study on the Concept of Operations (<span class="hlt">Con</span>Ops) for Reusable Booster System (RBS) centering on rapid turnaround and launch of a two-stage partially reusable payload delivery system (i.e., 8 hours between launches). The study was to develop rapid ground processing (aircraft like concepts) and identify areas for follow-on study, technology needs, and proof-of-concept demonstrations.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3278648','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3278648"><span>Pros and <span class="hlt">cons</span> of phage therapy</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Loc-Carrillo, Catherine</p> <p>2011-01-01</p> <p>Many publications list advantages and disadvantages associated with phage therapy, which is the use of bacterial viruses to combat populations of nuisance or pathogenic bacteria. The goal of this commentary is to discuss many of those issues in a single location. In terms of “Pros,” for example, phages can be bactericidal, can increase in number over the course of treatment, tend to only minimally disrupt normal flora, are equally effective against antibiotic-sensitive and antibiotic-resistant bacteria, often are easily discovered, seem to be capable of disrupting bacterial biofilms, and can have low inherent toxicities. In addition to these assets, we consider aspects of phage therapy that can contribute to its safety, economics, or convenience, but in ways that are perhaps less essential to the phage potential to combat bacteria. For example, autonomous phage transfer between animals during veterinary application could provide convenience or economic advantages by decreasing the need for repeated phage application, but is not necessarily crucial to therapeutic success. We also consider possible disadvantages to phage use as antibacterial agents. These “<span class="hlt">Cons</span>,” however, tend to be relatively minor. PMID:22334867</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29420529','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29420529"><span>Genes del receptor variable beta de células T en células circulantes de pacientes <span class="hlt">con</span> lupus eritematoso generalizado y sus familiares sanos.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Jakez-Ocampo, Juan; Paulín-Vera, Carmen María; Rivadeneyra-Espinoza, Liliana; Gómez-Martín, Diana; Carrillo-Maravilla, Eduardo; Lima, Guadalupe; Vargas-Rojas, María Inés; Pérez-Romano, Beatriz; Calva-Cevenini, Gabriella; García-Carrasco, Mario; Ruiz-Argüelles, Alejandro; Llorente, Luis</p> <p></p> <p>Se investigó la proporción de la expresión génica del receptor variable beta de células T (Vβ TCR) en linfocitos periféricos CD3+ en pacientes <span class="hlt">con</span> lupus eritematoso generalizado (LEG) familiar y no familiar. El repertorio de Vβ TCR se estudió en 14 familias que presentaban más de un miembro <span class="hlt">con</span> LEG. El uso de Vβ TCR en pacientes <span class="hlt">con</span> LEG (n = 27) se comparó <span class="hlt">con</span> el de los miembros sanos de estas familias (n = 47), <span class="hlt">con</span> 37 pacientes <span class="hlt">con</span> LEG esporádico y <span class="hlt">con</span> 15 controles sanos. La expresión del repertorio de Vβ TCR se estudió por citometría de flujo multiparamétrica utilizando un arreglo de 24 diferentes anticuerpos monoclonales específicos de genes familiares para Vβ TCR. Se encontró el mismo perfil de expresión en las comparaciones entre los casos de LEG esporádico y familiar, así como en los consanguíneos sanos de las familias multicasos, que incluía una expresión incrementada de Vβ 5.2, Vβ 11 y Vβ 16, y una menor expresión de Vβ 3, Vβ4, Vβ 7.1 y Vβ 7. De manera interesante, solo Vβ 17 se expresó de modo diferente entre casos familiares y esporádicos de LEG. Igualmente, la expresión incrementada de Vβ 9 fue el distintivo entre los casos de LEG familiar (casos y consanguíneos sanos) y los controles sanos. Estos resultados refuerzan la noción de que el perfil final del repertorio Vβ TCR observado en LEG familiar y no familiar parece surgir de la interacción de factores genéticos, ambientales e inmunorreguladores, además de que pueden explicar las alteraciones inmunitarias que se observan en los consanguíneos sanos de pacientes <span class="hlt">con</span> LEG. Copyright: © 2018 SecretarÍa de Salud</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26021098','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26021098"><span>[Modern tribology in total hip arthroplasty: pros and <span class="hlt">cons</span>].</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Gómez-García, F</p> <p>2014-01-01</p> <p>The wear products and adverse reactions that occur on bearing surfaces represent one of the greatest challenges in prosthetic replacements, as the latter experience increasing demands due to the large number of young and older adult patients that have a long life expectancy and remarkable activity. The purpose of this review is to analyze the pros and <span class="hlt">cons</span> of the new advances in the bearing components of the articular surfaces of current total hip arthroplasties. We also discuss the strategies used historically, their problems, results and the surgeon's role in prescribing the tribologic couple that best fits each patient's needs. We conclude with practical recommendations for the prescription and management of the latest articular couples for total hip arthroplasty.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://files.eric.ed.gov/fulltext/ED462269.pdf','ERIC'); return false;" href="http://files.eric.ed.gov/fulltext/ED462269.pdf"><span><span class="hlt">Con</span>Map: Investigating New Computer-Based Approaches to Assessing Conceptual Knowledge Structure in Physics.</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Beatty, Ian D.</p> <p></p> <p>There is a growing consensus among educational researchers that traditional problem-based assessments are not effective tools for diagnosing a student's knowledge state and for guiding pedagogical intervention, and that new tools grounded in the results of cognitive science research are needed. The <span class="hlt">Con</span>Map ("Conceptual Mapping") project, described…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4356569','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4356569"><span>Protective Effects of Astaxanthin on <span class="hlt">Con</span>A-Induced Autoimmune Hepatitis by the JNK/p-JNK Pathway-Mediated Inhibition of Autophagy and Apoptosis</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Liu, Tong; Wang, Junshan; Dai, Weiqi; Wang, Fan; Zheng, Yuanyuan; Chen, Kan; Li, Sainan; Abudumijiti, Huerxidan; Zhou, Zheng; Wang, Jianrong; Lu, Wenxia; Zhu, Rong; Yang, Jing; Zhang, Huawei; Yin, Qin; Wang, Chengfen; Zhou, Yuqing; Lu, Jie; Zhou, Yingqun; Guo, Chuanyong</p> <p>2015-01-01</p> <p>Objective Astaxanthin, a potent antioxidant, exhibits a wide range of biological activities, including antioxidant, atherosclerosis and antitumor activities. However, its effect on concanavalin A (<span class="hlt">Con</span>A)-induced autoimmune hepatitis remains unclear. The aim of this study was to investigate the protective effects of astaxanthin on <span class="hlt">Con</span>A-induced hepatitis in mice, and to elucidate the mechanisms of regulation. Materials and Methods Autoimmune hepatitis was induced in in Balb/C mice using <span class="hlt">Con</span>A (25 mg/kg), and astaxanthin was orally administered daily at two doses (20 mg/kg and 40 mg/kg) for 14 days before <span class="hlt">Con</span>A injection. Levels of serum liver enzymes and the histopathology of inflammatory cytokines and other maker proteins were determined at three time points (2, 8 and 24 h). Primary hepatocytes were pretreated with astaxanthin (80 μM) in vitro 24 h before stimulation with TNF-α (10 ng/ml). The apoptosis rate and related protein expression were determined 24 h after the administration of TNF-α. Results Astaxanthin attenuated serum liver enzymes and pathological damage by reducing the release of inflammatory factors. It performed anti-apoptotic effects via the descending phosphorylation of Bcl-2 through the down-regulation of the JNK/p-JNK pathway. Conclusion This research firstly expounded that astaxanthin reduced immune liver injury in <span class="hlt">Con</span>A-induced autoimmune hepatitis. The mode of action appears to be downregulation of JNK/p-JNK-mediated apoptosis and autophagy. PMID:25761053</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2013APS..MAR.Z3004T','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2013APS..MAR.Z3004T"><span>Integrated Concentration in Science (i<span class="hlt">Cons</span>): Undergraduate Education Through Interdisciplinary, Team-Based, Real-World Problem Solving</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Tuominen, Mark</p> <p>2013-03-01</p> <p>Attitude, Skills, Knowledge (ASK) - In this order, these are fundamental characteristics of scientific innovators. Through first-hand practice in using science to unpack and solve complex real-world problems, students can become self-motivated scientific leaders. This presentation describes the pedagogy of a recently developed interdisciplinary undergraduate science education program at the University of Massachusetts Amherst focused on addressing global challenges with scientific solutions. Integrated Concentration in Science (i<span class="hlt">Cons</span>) is an overarching concentration program that supplements the curricula provided within each student's chosen major. i<span class="hlt">Cons</span> is a platform for students to perform student-led research in interdisciplinary collaborative teams. With a schedule of one course per year over four years, the cohort of students move through case studies, analysis of real-world problems, development of potential solutions, integrative communication, laboratory practice, and capstone research projects. In this presentation, a track emphasizing renewable energy science is used to illustrate the i<span class="hlt">Cons</span> pedagogical methods. This includes discussion of a third-year laboratory course in renewable energy that is educationally scaffolded: beginning with a boot camp in laboratory techniques and culminating with student-designed research projects. Among other objectives, this course emphasizes the practice of using reflection and redesign, as a means of generating better solutions and embedding learning for the long term. This work is supported in part by NSF grant DUE-1140805.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24816093','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24816093"><span>Accurate macromolecular crystallographic refinement: incorporation of the linear scaling, semiempirical quantum-mechanics program Div<span class="hlt">Con</span> into the PHENIX refinement package.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Borbulevych, Oleg Y; Plumley, Joshua A; Martin, Roger I; Merz, Kenneth M; Westerhoff, Lance M</p> <p>2014-05-01</p> <p>Macromolecular crystallographic refinement relies on sometimes dubious stereochemical restraints and rudimentary energy functionals to ensure the correct geometry of the model of the macromolecule and any covalently bound ligand(s). The ligand stereochemical restraint file (CIF) requires a priori understanding of the ligand geometry within the active site, and creation of the CIF is often an error-prone process owing to the great variety of potential ligand chemistry and structure. Stereochemical restraints have been replaced with more robust functionals through the integration of the linear-scaling, semiempirical quantum-mechanics (SE-QM) program Div<span class="hlt">Con</span> with the PHENIX X-ray refinement engine. The PHENIX/Div<span class="hlt">Con</span> package has been thoroughly validated on a population of 50 protein-ligand Protein Data Bank (PDB) structures with a range of resolutions and chemistry. The PDB structures used for the validation were originally refined utilizing various refinement packages and were published within the past five years. PHENIX/Div<span class="hlt">Con</span> does not utilize CIF(s), link restraints and other parameters for refinement and hence it does not make as many a priori assumptions about the model. Across the entire population, the method results in reasonable ligand geometries and low ligand strains, even when the original refinement exhibited difficulties, indicating that PHENIX/Div<span class="hlt">Con</span> is applicable to both single-structure and high-throughput crystallography.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28084436','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28084436"><span>Stress barriers controlling lateral migration of magma revealed by seismic tomography.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Martí, J; Villaseñor, A; Geyer, A; López, C; Tryggvason, A</p> <p>2017-01-13</p> <p>Understanding how monogenetic volcanic systems work requires full comprehension of the local and regional stresses that govern magma migration inside them and why/how they seem to change from one eruption to another. During the 2011-2012 El <span class="hlt">Hierro</span> eruption (Canary Islands) the characteristics of unrest, including a continuous change in the location of seismicity, made the location of the future vent unpredictable, so short term hazard assessment was highly imprecise. A 3D P-wave velocity model is obtained using arrival times of the earthquakes occurred during that pre-eruptive unrest and several latter post-eruptive seismic crises not related to further eruptions. This model reveals the rheological and structural complexity of the interior of El <span class="hlt">Hierro</span> volcanic island. It shows a number of stress barriers corresponding to regional tectonic structures and blocked pathways from previous eruptions, which controlled ascent and lateral migration of magma and, together with the existence of N-S regional compression, reduced its options to find a suitable path to reach the surface and erupt.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017NatSR...740757M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017NatSR...740757M"><span>Stress barriers controlling lateral migration of magma revealed by seismic tomography</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Martí, J.; Villaseñor, A.; Geyer, A.; López, C.; Tryggvason, A.</p> <p>2017-01-01</p> <p>Understanding how monogenetic volcanic systems work requires full comprehension of the local and regional stresses that govern magma migration inside them and why/how they seem to change from one eruption to another. During the 2011-2012 El <span class="hlt">Hierro</span> eruption (Canary Islands) the characteristics of unrest, including a continuous change in the location of seismicity, made the location of the future vent unpredictable, so short term hazard assessment was highly imprecise. A 3D P-wave velocity model is obtained using arrival times of the earthquakes occurred during that pre-eruptive unrest and several latter post-eruptive seismic crises not related to further eruptions. This model reveals the rheological and structural complexity of the interior of El <span class="hlt">Hierro</span> volcanic island. It shows a number of stress barriers corresponding to regional tectonic structures and blocked pathways from previous eruptions, which controlled ascent and lateral migration of magma and, together with the existence of N-S regional compression, reduced its options to find a suitable path to reach the surface and erupt.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5233990','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5233990"><span>Stress barriers controlling lateral migration of magma revealed by seismic tomography</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Martí, J.; Villaseñor, A.; Geyer, A.; López, C.; Tryggvason, A.</p> <p>2017-01-01</p> <p>Understanding how monogenetic volcanic systems work requires full comprehension of the local and regional stresses that govern magma migration inside them and why/how they seem to change from one eruption to another. During the 2011–2012 El <span class="hlt">Hierro</span> eruption (Canary Islands) the characteristics of unrest, including a continuous change in the location of seismicity, made the location of the future vent unpredictable, so short term hazard assessment was highly imprecise. A 3D P-wave velocity model is obtained using arrival times of the earthquakes occurred during that pre-eruptive unrest and several latter post-eruptive seismic crises not related to further eruptions. This model reveals the rheological and structural complexity of the interior of El <span class="hlt">Hierro</span> volcanic island. It shows a number of stress barriers corresponding to regional tectonic structures and blocked pathways from previous eruptions, which controlled ascent and lateral migration of magma and, together with the existence of N-S regional compression, reduced its options to find a suitable path to reach the surface and erupt. PMID:28084436</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26182917','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26182917"><span>Pro<span class="hlt">Con</span> - PROteomics CONversion tool.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Mayer, Gerhard; Stephan, Christian; Meyer, Helmut E; Kohl, Michael; Marcus, Katrin; Eisenacher, Martin</p> <p>2015-11-03</p> <p>With the growing amount of experimental data produced in proteomics experiments and the requirements/recommendations of journals in the proteomics field to publicly make available data described in papers, a need for long-term storage of proteomics data in public repositories arises. For such an upload one needs proteomics data in a standardized format. Therefore, it is desirable, that the proprietary vendor's software will integrate in the future such an export functionality using the standard formats for proteomics results defined by the HUPO-PSI group. Currently not all search engines and analysis tools support these standard formats. In the meantime there is a need to provide user-friendly free-to-use conversion tools that can convert the data into such standard formats in order to support wet-lab scientists in creating proteomics data files ready for upload into the public repositories. Pro<span class="hlt">Con</span> is such a conversion tool written in Java for conversion of proteomics identification data into standard formats mzIdentML and Pride XML. It allows the conversion of Sequest™/Comet .out files, of search results from the popular and often used ProteomeDiscoverer® 1.x (x=versions 1.1 to1.4) software and search results stored in the LIMS systems ProteinScape® 1.3 and 2.1 into mzIdentML and PRIDE XML. This article is part of a Special Issue entitled: Computational Proteomics. Copyright © 2015. Published by Elsevier B.V.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2843427','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2843427"><span>Desarrollo de la Escala sobre el Estigma Relacionado <span class="hlt">con</span> el VIH/SIDA para Profesionales de la Salud mediante el uso de métodos mixtos123</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Varas-Díaz, Nelson; Neilands, Torsten B.; Guilamo-Ramos, Vincent; Cintrón Bou, Francheska N.</p> <p>2009-01-01</p> <p>El estigma relacionado <span class="hlt">con</span> el VIH/SIDA continúa siendo un obstáculo para la prevención primaria y secundaria del VIH. Las consecuencias para las personas que viven <span class="hlt">con</span> la enfermedad han sido muy documentadas y continúan siendo una gran preocupación para las personas que proveen servicios de salud y para aquellas que investigan el tema. Estas consecuencias son preocupantes cuando el estigma emana de profesionales de la salud porque se puede limitar el acceso a los servicios. Uno de los principales obstáculos para la investigación del estigma relacionado <span class="hlt">con</span> el VIH en Puerto Rico es la falta de instrumentos cuantitativos para evaluar las manifestaciones del estigma entre profesionales de la salud. El objetivo principal de este estudio fue desarrollar y probar las propiedades psicométricas de una escala sobre el estigma relacionado <span class="hlt">con</span> el VIH/SIDA culturalmente apropiada para personas que proveen servicios de salud puertorriqueñas y desarrollar una versión corta de la escala que pudiera usarse en escenarios clínicos <span class="hlt">con</span> tiempo limitado. El instrumento desarrollado estuvo basado en evidencia cualitativa recopilada entre profesionales y estudiantes de profesiones de la salud puertorriqueños/as (n=80) y administrado a una muestra de 421 profesionales de la salud en adiestramiento. La escala contenía 12 dimensiones del estigma relacionado <span class="hlt">con</span> el VIH/SIDA. El análisis cuantitativo corroboró 11 de ellas, teniendo como resultado un instrumento <span class="hlt">con</span> validez y confiabilidad satisfactoria. Estas dimensiones, a su vez, fueron subcomponentes de un factor de estigma general superior. PMID:20333258</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_12");'>12</a></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li class="active"><span>14</span></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_14 --> <div id="page_15" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li class="active"><span>15</span></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="281"> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5087992','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5087992"><span>Fragilidad y su asociación <span class="hlt">con</span> mortalidad, hospitalizaciones y dependencia funcional en mexicanos de 60 años o más</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>de León González, Enrique Díaz; Pérez, Héctor Eloy Tamez; Hermosillo, Hugo Gutiérrez; Rodríguez, Javier Armando Cedillo; Torres, Gabriela</p> <p>2016-01-01</p> <p>Fundamento y objetivo Determinar la asociación entre fragilidad y mortalidad, dependencia funcional, caídas y hospitalizaciones en el Estudio Nacional de Salud y Envejecimiento en México (ENASEM). Sujetos y métodos Estudio prospectivo poblacional en México en el que se seleccionaron sujetos de 60 años o más, que fueron evaluados en las variables de fragilidad durante la primera vuelta del estudio en el año 2001 y que incluyó: dificultad para levantarse de una silla después de haber estado sentado(a) durante largo tiempo, pérdida de peso de 5 kilogramos o más en los últimos dos años y falta de energía. Los sujetos fueron catalogados como robustos, prefrágiles y frágiles cuando tenían cero, una o dos de las características anteriores, respectivamente. La mortalidad, hospitalizaciones, caídas y dependencia funcional fueron evaluadas en la segunda vuelta del estudio en el año 2003. Se calculó el riesgo relativo para cada una de las complicaciones, así como análisis multivariado <span class="hlt">con</span> regresión de Cox para el caso de mortalidad y regresión logística para el resto. Resultados Los estados de prefragilidad y fragilidad se asociaron independientemente <span class="hlt">con</span> mortalidad, <span class="hlt">con</span> índices de riesgo ajustados de 1,61 (intervalo de confianza del 95% [IC 95%] 1,01-2,55) y 1,94 (IC 95% 1,20-3,13), respectivamente. Sólo el estado de fragilidad se asoció independientemente <span class="hlt">con</span> hospitalización y dependencia funcional, <span class="hlt">con</span> una razón de momios ajustada de 1,53 (IC 95% 1,13-2,07) y 3,07 (IC 95% 1,76-5,34), respectivamente. No hubo asociación entre los estados de prefragilidad y fragilidad <span class="hlt">con</span> caídas. Conclusión El estado de fragilidad se asocia independientemente <span class="hlt">con</span> mortalidad, hospitalizaciones y disfuncionalidad en actividades básicas de la vida diaria en los siguientes dos años en población mexicana. PMID:21612803</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1996BAAA...40Q..37A','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1996BAAA...40Q..37A"><span>La interacción de estrellas WN <span class="hlt">con</span> el medio circundante</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Arnal, M.; Cappa, C.; Rizzo, J. R.; Cichovolski, S.</p> <p></p> <p>Se presentan resultados preliminares de un estudio de la distribución del hidrógeno neutro en los alrededores de estrellas WR de la serie del nitrógeno. Los datos observacionales de la línea de 21 cm provienen de un relevamineto de baja resolución angular (36'), así como de observaciones de resolución angular intermedia (9') tomadas <span class="hlt">con</span> el radiotelescopio de Effelsberg. Este análisis ha permitido detectar cavidades y envolturas de H I en expansión vinculadas a las estrellas que componen la muestra.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29874712','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29874712"><span>Impacto metabólico e inflamatorio de una comida rica en grasas saturadas y su relación <span class="hlt">con</span> la obesidad abdominal.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Alayón, Alicia Norma; Rivadeneira, Ana Patricia; Herrera, Carlos; Guzmán, Heidy; Arellano, Dioneris; Echeverri, Isabella</p> <p>2018-05-01</p> <p>Introducción. La etapa posprandial se asocia <span class="hlt">con</span> el incremento de marcadores relacionados <span class="hlt">con</span> el riesgo cardiovascular, cuya intensidad depende del estado metabólico.Objetivo. Determinar el impacto de la ingestión de una comida rica en grasas saturadas sobre el perfil metabólico e inflamatorio y su relación <span class="hlt">con</span> la obesidad abdominal.Materiales y métodos. Se hizo un ensayo clínico en 42 individuos (21 <span class="hlt">con</span> obesidad abdominal). Se midieron, en sangre, la glucosa, la insulina, el perfil lipídico, la proteína C reactiva, los lipopolisacáridos y la interleucina 6, en ayunas y después de la ingestión.Resultados. Además de la obesidad, se registró la presencia de resistencia a la insulina y de niveles elevados de triacilglicéridos y proteína C reactiva en ayunas. Asimismo, se detectaron niveles posprandiales más elevados de glucosa, insulina y triacilglicéridos. La interleucina 6 disminuyó en el grupo de personas sin obesidad y los lipopolisacáridos aumentaron en ambos grupos.Conclusión. La ingestión de una comida rica en grasas saturadas produjo un mayor impacto en las variables glucémicas en el grupo <span class="hlt">con</span> obesidad y, aunque afectó de forma similar los lípidos en ambos grupos, el incremento de triacilglicéridos fue mayor en presencia de una concentración basal elevada y promovió el aumento de lipopolisacáridos. El estado inflamatorio basal y posprandial afectó en mayor medida al grupo <span class="hlt">con</span> obesidad. El momento posprandial reflejó el estado más frecuente de los individuos en un día normal y permitió evidenciar la capacidad de respuesta metabólica frente a la ingestión de alimentos, así como los estados tempranos de riesgo metabólico.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2010EGUGA..1213872W','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2010EGUGA..1213872W"><span>A <span class="hlt">con</span>-focal setup for micro-XRF experiments using diamond anvil cells</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Wilke, Max; Rickers, Karen; Vincze, Laszlo; Schmidt, Christian; Borchert, Manuela; Pascarelli, Sakura</p> <p>2010-05-01</p> <p>In this contribution we introduce an experimental setup to perform <span class="hlt">con</span>-focal micro X-ray fluorescence measurements in situ in samples at high temperatures and pressures in diamond anvil cells (DAC) (e.g. Schmidt et al. 2007). The <span class="hlt">con</span>-focal arrangement is used to suppress the background in X-ray fluorescence (XRF) spectra that stems from elastic and inelastic scattering of the diamond anvils. The setup is based on a focusing optic in the incident beam that reaches a spot of 5-10 μm and a focusing poly-capillary in front of an energy-dispersive solid-state detector. The detector poly-capillary is designed to work at a very long working distance of 50 mm in order to collect the radiation from the center of the DAC at 90° to the incident beam. The probing volume is defined by the two foci and has a size of ca. 300 μm at 8 keV and 150 μm at 19 keV as measured by scans through thin metal foils. Comparison of XRF spectra acquired with a usual detector collimator and spectra recorded with the detector capillary shows a strong suppression of XRF signal generated outside the probed volume, i.e. XRF from the gasket material and signal from elastic and Compton scattering by the diamond anvils. The ratio of the Zr K-alpha fluorescence peak to the peak of the Compton scattering changes from 0.5 (collimator) to 1.26 (detector capillary) for a ca. 1000 ppm Zr standard solution and an incident beam energy of 20 keV. For a standard solution containing ca. 1000 ppm Hf, the ratio of the L-alpha to the Compton signal increases to 6 using the detector capillary and an incident beam energy of 9.7 keV. Thus, the <span class="hlt">con</span>-focal setup substantially improves the fluorescence to background ratio. This will result in higher sensitivities for dilute elements in the sample chamber of the DAC. Furthermore, the possibilities of interference of the sample's signal with signal from the sample environment are greatly reduced. In a broader sense, the setup can also be applied to other confined samples</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4906251','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4906251"><span>Caffe <span class="hlt">con</span> Troll: Shallow Ideas to Speed Up Deep Learning</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Hadjis, Stefan; Abuzaid, Firas; Zhang, Ce; Ré, Christopher</p> <p>2016-01-01</p> <p>We present Caffe <span class="hlt">con</span> Troll (CcT), a fully compatible end-to-end version of the popular framework Caffe with rebuilt internals. We built CcT to examine the performance characteristics of training and deploying general-purpose convolutional neural networks across different hardware architectures. We find that, by employing standard batching optimizations for CPU training, we achieve a 4.5× throughput improvement over Caffe on popular networks like CaffeNet. Moreover, with these improvements, the end-to-end training time for CNNs is directly proportional to the FLOPS delivered by the CPU, which enables us to efficiently train hybrid CPU-GPU systems for CNNs. PMID:27314106</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27314106','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27314106"><span>Caffe <span class="hlt">con</span> Troll: Shallow Ideas to Speed Up Deep Learning.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Hadjis, Stefan; Abuzaid, Firas; Zhang, Ce; Ré, Christopher</p> <p>2015-01-01</p> <p>We present Caffe <span class="hlt">con</span> Troll (CcT), a fully compatible end-to-end version of the popular framework Caffe with rebuilt internals. We built CcT to examine the performance characteristics of training and deploying general-purpose convolutional neural networks across different hardware architectures. We find that, by employing standard batching optimizations for CPU training, we achieve a 4.5× throughput improvement over Caffe on popular networks like CaffeNet. Moreover, with these improvements, the end-to-end training time for CNNs is directly proportional to the FLOPS delivered by the CPU, which enables us to efficiently train hybrid CPU-GPU systems for CNNs.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29059395','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29059395"><span>Moderator's view: High-volume plasma exchange: pro, <span class="hlt">con</span> and consensus.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Kaplan, Andre A</p> <p>2017-09-01</p> <p>I have been asked to comment on the pro and <span class="hlt">con</span> opinions regarding high-volume plasma exchange. The authors of both positions have provided cogent arguments and a reasonable approach to choosing the exchange volume for any given therapeutic plasma exchange. The major issue of relevance in this discussion is the nature of the toxins targeted for removal. These parameters include molecular weight, the apparent volume of distribution, the degree of protein binding, the biologic and chemical half-life, and the severity and rapidity of its toxicity. © The Author 2017. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/21062238','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/21062238"><span>Nano anti-cancer drugs: pros and <span class="hlt">cons</span> and future perspectives.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Ali, Imran</p> <p>2011-02-01</p> <p>For last one decade, scientists are working for developing nano anti-cancer drugs with claim of ideal ones due to their targeted chemotherapic nature. These drugs have many beneficial properties such as targeted drug delivery and gene therapy modalities with minimum side effects. This article describes pros and <span class="hlt">cons</span> and future perspectives of nano anti-cancer drugs. Efforts have been made to address importance, special features, toxicities (general, blood identities, immune system and environmental) and future perspectives of nano anti-cancer drugs. It was concluded that nano anti-cancer drugs may be magic bullet drugs for cancer treatment leading to bright future of the whole world.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28091967','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28091967"><span>Balancing Ethical Pros and <span class="hlt">Cons</span> of Stem Cell Derived Gametes.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Segers, Seppe; Mertes, Heidi; de Wert, Guido; Dondorp, Wybo; Pennings, Guido</p> <p>2017-07-01</p> <p>In this review we aim to provide an overview of the most important ethical pros and <span class="hlt">cons</span> of stem cell derived gametes (SCD-gametes), as a contribution to the debate about reproductive tissue engineering. Derivation of gametes from stem cells holds promising applications both for research and for clinical use in assisted reproduction. We explore the ethical issues connected to gametes derived from embryonic stem cells (both patient specific and non-patient specific) as well as those related to gametes derived from induced pluripotent stem cells. The technology of SCD-gametes raises moral concerns of how reproductive autonomy relates to issues of embryo destruction, safety, access, and applications beyond clinical infertility.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27933181','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27933181"><span>What are the pros and <span class="hlt">cons</span> of electronically monitoring inhaler use in asthma? A multistakeholder perspective.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Howard, Sam; Lang, Alexandra; Sharples, Sarah; Shaw, Dominick</p> <p>2016-01-01</p> <p>Electronic monitoring devices (EMDs) are the optimal method for collecting objective data on inhaler use in asthma. Recent research has investigated the attitudes of patients with asthma towards these devices. However, no research to date has formally considered the opinions of stakeholders and decision-makers in asthma care. These individuals have important clinical requirements that need to be taken into account if EMDs are to be successfully provisioned, making collecting their opinions on the key barriers facing these devices a valuable process. Three rounds of surveys in a Delphi format were used to assess the most important pros and <span class="hlt">cons</span> of EMDs for asthma care in a sample of 31 stakeholders which included healthcare professionals and members of clinical commissioning groups. The respondents identified 29 pros and 32 <span class="hlt">cons</span>. Pros that were rated as most important included new visual evidence to aid clinical discussions with a patient and an increase in patient involvement and motivation. The <span class="hlt">cons</span> that were rated as most important included a need for more clinical evidence of the effectiveness of EMDs, as well as better clarity over who has responsibilities in managing, interpreting and discussing data with a patient. The research provides a guide for EMD developers by highlighting where these devices may provide the most benefit as well as prioritising the key issues that need addressing if they are to be used effectively in everyday asthma care.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5133420','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5133420"><span>What are the pros and <span class="hlt">cons</span> of electronically monitoring inhaler use in asthma? A multistakeholder perspective</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Howard, Sam; Lang, Alexandra; Sharples, Sarah; Shaw, Dominick</p> <p>2016-01-01</p> <p>Introduction Electronic monitoring devices (EMDs) are the optimal method for collecting objective data on inhaler use in asthma. Recent research has investigated the attitudes of patients with asthma towards these devices. However, no research to date has formally considered the opinions of stakeholders and decision-makers in asthma care. These individuals have important clinical requirements that need to be taken into account if EMDs are to be successfully provisioned, making collecting their opinions on the key barriers facing these devices a valuable process. Methods Three rounds of surveys in a Delphi format were used to assess the most important pros and <span class="hlt">cons</span> of EMDs for asthma care in a sample of 31 stakeholders which included healthcare professionals and members of clinical commissioning groups. Results The respondents identified 29 pros and 32 <span class="hlt">cons</span>. Pros that were rated as most important included new visual evidence to aid clinical discussions with a patient and an increase in patient involvement and motivation. The <span class="hlt">cons</span> that were rated as most important included a need for more clinical evidence of the effectiveness of EMDs, as well as better clarity over who has responsibilities in managing, interpreting and discussing data with a patient. Conclusions The research provides a guide for EMD developers by highlighting where these devices may provide the most benefit as well as prioritising the key issues that need addressing if they are to be used effectively in everyday asthma care. PMID:27933181</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28788387','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28788387"><span>Magnetic Phase Transition in Ion-Irradiated Ultrathin <span class="hlt">CoN</span> Films via Magneto-Optic Faraday Effect.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Su, Chiung-Wu; Chang, Yen-Chu; Chang, Sheng-Chi</p> <p>2013-11-15</p> <p>The magnetic properties of 1 nm thick in-plane anisotropic Co ultrathin film on ZnO(0001) were investigated through successive 500 eV nitrogen-ion sputtering. Magneto-optical Faraday effects were used to observe the evolution of the ion-irradiated sample in longitudinal and perpendicular magnetic fields. The ferromagnetic phase of the initial in-plane anisotropic fcc β-Co phase transformation to β-Co(N) phase was terminated at paramagnetic <span class="hlt">CoN</span> x phase. In-plane anisotropy with weak out-of-plane anisotropy of the Co/ZnO sample was initially observed in the as-grown condition. In the sputtering process, the N⁺ ions induced simultaneous sputtering and doping. An abrupt spin reorientation behavior from in-plane to out-of-plane was found under prolonged sputtering condition. The existence of perpendicular anisotropy measured from the out-of-plane Faraday effect may be attributed to the co-existence of residual β-Co and Co₄N exchange bonding force by the gradual depletion of <span class="hlt">Co-N</span> thickness.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://eric.ed.gov/?q=insurance+AND+industry&pg=7&id=ED274916','ERIC'); return false;" href="https://eric.ed.gov/?q=insurance+AND+industry&pg=7&id=ED274916"><span>Mandated Mental Health Insurance: A Complex Case of Pros and <span class="hlt">Cons</span>. Human Resources Series.</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Paterson, Andrea</p> <p>1986-01-01</p> <p>The pros and <span class="hlt">cons</span> of state laws mandating mental health insurance are discussed in this report. The history of a 1985 Supreme Court case which held that states could mandate mental health benefits introduces the report. In an overview of the issue, the long-standing argument between the insurance industry and the mental health establishment is…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2012AGUFM.B53D0698B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2012AGUFM.B53D0698B"><span>Formation of mixed-layer structures in smectites intercalated with tryptone</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Block, K. A.; Trusiak, A.; Steiner, J. C.; Katz, A.; Gottlieb, P.; Alimova, A.</p> <p>2012-12-01</p> <p>Stable clay-protein complexes are fundamental to studies of the critical zone, terrestrial ecosystems, pharmacology, and industrial applications such as bioremediation. Two sets of montmorillonite clays were purified and made homoionic for Na and Mg. Mg-montmorillonite and Na-montmorillonite were mixed with tryptone (casein digest) in a 9:1 and 18:1 clay:tryptone ratio, resulting in the formation of reversible intercalated structures. X-ray diffraction analysis of the protein-clay complexes produced profiles consisting of two peaks associated with the smectite 001 reflection and a related tryptone-packet peak similar to that produced by a mixed layer clay structure. Shifts in the 002, 003, and 004 diffraction maxima are attributed to disorder caused by the interaction with the protein. Line broadening in the smectite-tryptone XRD spectra is interpreted to be the result of interlayer absorption. Adsorption produces coherent crystalline packets of regularly interbedded tryptone and smectite platelets. SEM images reveal clay platelets with upwardly rolled edges that tend toward cylindrical structures with the production of occasional tubes in the smaller platelet size range as noted for organic compound-kaolinite intercalation reported by <span class="hlt">Fenoll</span> Hach-Ali and Weiss (1969). Reference: <span class="hlt">Fenoll</span> Hach-Ali, P.F., Weiss, A., 1969. Estudio de la reaccion de caolinita y N-metilform- amida. Quimica LXV, 769-790. Scanning electron micrograph of tryptone-intercalated clay platelets exhibiting rolled edge structure.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/20160010100','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/20160010100"><span>Air Traffic Management Technology Demonstration-1 Concept of Operations (ATD-1 <span class="hlt">Con</span>Ops), Version 3.0</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Baxley, Brian T.; Johnson, William C.; Scardina, John; Shay, Richard F.</p> <p>2016-01-01</p> <p>This document describes the goals, benefits, technologies, and procedures of the Concept of Operations (<span class="hlt">Con</span>Ops) for the Air Traffic Management (ATM) Technology Demonstration #1 (ATD-1), and provides an update to the previous versions of the document [ref 1 and ref 2].</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29616593','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29616593"><span>Understanding the pros and <span class="hlt">cons</span> of organ donation decision-making: Decisional balance and expressing donation intentions among African Americans.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Flemming, Shauna St Clair; Redmond, Nakeva; Williamson, Dana Hz; Thompson, Nancy J; Perryman, Jennie P; Patzer, Rachel E; Arriola, Kimberly Jacob</p> <p>2018-04-01</p> <p>Increasing public commitment to organ donation is critical to improving donor kidney availability for end-stage renal disease patients desiring transplant. This study surveyed ( N = 1339) African Americans, measuring perceived pros relative to <span class="hlt">cons</span> of organ donation, to evaluate an existing Transtheoretical Model decisional balance scale and associations between decisional balance and expressing donation intentions. Findings supported the existing scale structure. More positive decisional balance ratios were associated with 1.76 times the odds of expressing intentions (95% confidence interval = 1.52-2.04). Pros were more strongly linked to donation intentions than <span class="hlt">cons</span>. Greater understanding of organ donation decision-making is valuable for informing interventions that encourage donation.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1617062','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1617062"><span>Cannabinoids and cancer: pros and <span class="hlt">cons</span> of an antitumour strategy</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Bifulco, Maurizio; Laezza, Chiara; Pisanti, Simona; Gazzerro, Patrizia</p> <p>2006-01-01</p> <p>In the last two decades, research has dramatically increased the knowledge of cannabinoids biology and pharmacology. In mammals, compounds with properties similar to active components of Cannabis sativa, the so called ‘endocannabinoids', have been shown to modulate key cell-signalling pathways involved in cancer cell growth, invasion and metastasis. To date, cannabinoids have been licensed for clinical use as palliative treatment of chemotherapy, but increased evidences showed direct antiproliferative actions of cannabinoid agonists on several tumour cells in vitro and in animal models. In this article, we will review the principal molecular pathways modulated by cannabinoids on cancer and summarize pros and <span class="hlt">cons</span> evidence on the possible future use of endocannabinoid-based drugs in cancer therapy. PMID:16501583</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29420514','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29420514"><span>La mortalidad en adolescentes <span class="hlt">con</span> cáncer: características clinicoepidemiológicas de muerte y aspectos éticos emergentes.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Cicero-Oneto, Carlo Egysto; Mata-Valderrama, Guadalupe; Valdez-Martínez, Edith</p> <p></p> <p>Describir los aspectos epidemiológicos, clínicos y éticos de la mortalidad de los adolescentes <span class="hlt">con</span> cáncer en -México. Se revisaron 63 expedientes clínicos de adolescentes (de 14 a 18 años de edad) <span class="hlt">con</span> cáncer, fallecidos entre 2011 y 2014, para obtener información clínica y epidemiológica de su muerte. Los sitios de estudio fueron tres hospitales de concentración en la Ciudad de México. De los 40 adolescentes <span class="hlt">con</span> criterios de fase terminal, 16 (40%) continuaron recibiendo tratamiento <span class="hlt">con</span> fines curativos. De los 51 cuyo lugar de muerte era conocido, 45 (88%) murieron en hospital. De los 41 que murieron dentro de los 30 días de su última hospitalización, las muertes fueron principalmente debidas a complicaciones (51%), a progresión de la enfermedad (41%) o bien fueron muertes en tratamiento paliativo (7%, 3/41). La práctica oncológica descansa en lo que es conocido como modelo biomédico. Los resultados del estudio sugieren y apoyan la urgente necesidad de implementar verdaderos servicios de cuidados paliativos, pero más importante que eso, está el ímpetu de poner la ética de la práctica clínica en acción, y de ese modo reforzar la buena práctica de la medicina. Copyright: © 2018 SecretarÍa de Salud</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3470459','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3470459"><span>Quick fix or long-term cure? Pros and <span class="hlt">cons</span> of bariatric surgery</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Madura, James A.</p> <p>2012-01-01</p> <p>The past decade has seen an enormous increase in the number of bariatric, or weight loss, operations performed. This trend is likely to continue, mirroring the epidemic of obesity around the world and its rising prevalence among children. Bariatric surgery is considered by many to be the most effective treatment for obesity in terms of maintenance of long-term weight loss and improvement in obesity-related comorbid conditions. Although overly simplified, the primary mechanisms of the surgical interventions currently utilized to treat obesity are the creation of a restrictive or malabsorptive bowel anatomy. Operations based on these mechanisms include the laparoscopic adjustable gastric band and laparoscopic vertical sleeve gastrectomy (considered primarily restrictive operations), the laparoscopic biliopancreatic diversion with or without a duodenal switch (primarily malabsorptive operation), and the laparoscopic Roux-en-Y gastric bypass (considered a combination restrictive and selective malabsorptive procedure). Each operation has pros and <span class="hlt">cons</span>. Important considerations, for the patient and surgeon alike, in the decision to proceed with bariatric surgery include the technical aspects of the operation, postoperative complications including long-term nutritional problems, magnitude of initial and sustained weight loss desired, and correction of obesity-related comorbidities. Herein, the pros and <span class="hlt">cons</span> of the contemporary laparoscopic bariatric operations are reviewed and ongoing controversies relating to bariatric surgery are discussed: appropriate patient selection, appropriate operation selection for an individual patient, surgeon selection, and how to measure success after surgery. PMID:23091563</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29062739','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29062739"><span>Pros and <span class="hlt">cons</span> of transcatheter aortic valve implantation (TAVI).</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Terré, Juan A; George, Isaac; Smith, Craig R</p> <p>2017-09-01</p> <p>Transcatheter aortic valve implantation (TAVI) or replacement (TAVR) was recently approved by the FDA for intermediate risk patients with severe aortic stenosis (AS). This technique was already worldwide adopted for inoperable and high-risk patients. Improved device technology, imaging analysis and operator expertise has reduced the initial worrisome higher complications rate associated with TAVR, making it comparable to surgical aortic valve replacement (SAVR). However, many answers need to be addressed before adoption in lower risk patients. This paper highlights the pros and <span class="hlt">cons</span> of TAVI based mostly on randomized clinical trials involving the two device platforms approved in the United States. We focused our analysis on metrics that will play a key role in expanding TAVR indication in healthier individuals. We review the significance and gave a perspective on paravalvular leak (PVL), valve performance, valve durability, leaflet thrombosis, stroke and pacemaker requirement.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li class="active"><span>15</span></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_15 --> <div id="page_16" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li class="active"><span>16</span></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="301"> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4819071','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4819071"><span>Encefalitis por anticuerpos contra el receptor de NMDA: experiencia <span class="hlt">con</span> seis pacientes pediátricos. Potencial eficacia del metotrexato</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Bravo-Oro, Antonio; Abud-Mendoza, Carlos; Quezada-Corona, Arturo; Dalmau, Josep; Campos-Guevara, Verónica</p> <p>2016-01-01</p> <p>Introducción La encefalitis por anticuerpos contra el receptor de N-metil-D-aspartato (NMDA) es una entidad cada vez más diagnosticada en edad pediátrica. A diferencia de los adultos, en muchos casos no se asocia a tumores y las manifestaciones iniciales en niños más frecuentes son crisis convulsivas y trastornos del movimiento, mientras que en los adultos predominan las alteraciones psiquiátricas. Casos clínicos Presentamos seis casos pediátricos confirmados <span class="hlt">con</span> anticuerpos contra la subunidad NR1 del receptor de NMDA en suero y líquido cefalorraquídeo. Cinco de los casos comenzaron <span class="hlt">con</span> crisis convulsivas como manifestación clínica inicial antes de desarrollar el cuadro clásico de esta entidad. En todos los casos se utilizaron esteroides como primera línea de tratamiento, <span class="hlt">con</span> los que sólo se observó control de las manifestaciones en uno, por lo que el resto de los pacientes requirió inmunomoduladores de segunda línea. Todos los pacientes recibieron metotrexato como tratamiento inmunomodulador para evitar recaídas y la evolución fue a la mejoría en todos ellos. Conclusiones En nuestra serie de pacientes <span class="hlt">con</span> encefalitis por anticuerpos contra el receptor de NMDA, ninguno se asoció a tumores. Todos los casos recibieron metotrexato por lo menos durante un año, no observamos eventos adversos clínicos ni por laboratorio, ni hubo secuelas neurológicas ni recaídas durante el tratamiento. Aunque es una serie pequeña y es deseable incrementar el número y tiempo de evolución, consideramos el metotrexato una excelente alternativa como tratamiento inmunomodulador para esta patología. PMID:24150952</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1998BAAA...42...64V','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1998BAAA...42...64V"><span>Confrontando teorías físicas <span class="hlt">con</span> la Cosmología</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Vucetich, H.</p> <p></p> <p>Hay numerosas teorías físicas que no pueden contrastarse <span class="hlt">con</span> el experimento en laboratorio y eso las hace poco interesantes como descripción de la naturaleza. Sin embargo, algunas de estas teorías tienen consecuencias cosmológicas observables y se abre la posibilidad de contrastación a través de la observación. Se discuten las observaciones capaces de poner a prueba tales teorías y se examinan ejemplos de teorías limitadas por la observación.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/18512367','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/18512367"><span>Hable <span class="hlt">con</span> Ella (Talk to Her) through the lens of gender.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Yanof, Judith A</p> <p>2008-04-01</p> <p>In the 2002 film Hable <span class="hlt">con</span> Ella (Talk to Her), Spanish writer-director Pedro Almodóvar plays with the ambiguity of gender, transcending conventional assumptions about "masculinity" and "femininity." Each of the four main characters holds complex, varied, and, in some cases, gender-bending gender identifications. The theme of gender plasticity is a prominent motif in this film. However, underlying the narrative, there is also a perverse subtext that relies on rigidly binary gender stereotypes to define relationships between men and women. Both these views of gender which operate dialectically, create a complex tapestry through which Almodóvar explores his characters' problems in attaining intimacy.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28713419','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28713419"><span>Population Structure, Genetic Diversity, and Evolutionary History of Kleinia neriifolia (Asteraceae) on the Canary Islands.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Sun, Ye; Vargas-Mendoza, Carlos F</p> <p>2017-01-01</p> <p>Kleinia neriifolia Haw. is an endemic species on the Canarian archipelago, this species is widespread in the coastal thicket of all the Canarian islands. In the present study, genetic diversity and population structure of K. neriifolia were investigated using chloroplast gene sequences and nuclear SSR (simple sequence repeat). The differentiation among island populations, the historical demography, and the underlying evolutionary scenarios of this species are further tested based on the genetic data. Chloroplast diversity reveals a strong genetic divergence between eastern islands (Gran Canaria, Fuerteventura, and Lanzarote) and western islands (EI <span class="hlt">Hierro</span>, La Palma, La Gomera, Tenerife), this west-east genetic divergence may reflect a very beginning of speciation. The evolutionary scenario with highest posterior probabilities suggests Gran Canaria as oldest population with a westward colonization path to Tenerife, La Gomera, La Palma, and EI <span class="hlt">Hierro</span>, and eastward dispersal path to Lanzarote through Fuerteventura. In the western islands, there is a slight decrease in the effective population size toward areas of recent colonization. However, in the eastern islands, the effective population size increase in Lanzarote relative to Gran Canaria and Fuerteventura. These results further our understanding of the evolution of widespread endemic plants within Canarian archipelago.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5492869','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5492869"><span>Population Structure, Genetic Diversity, and Evolutionary History of Kleinia neriifolia (Asteraceae) on the Canary Islands</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Sun, Ye; Vargas-Mendoza, Carlos F.</p> <p>2017-01-01</p> <p>Kleinia neriifolia Haw. is an endemic species on the Canarian archipelago, this species is widespread in the coastal thicket of all the Canarian islands. In the present study, genetic diversity and population structure of K. neriifolia were investigated using chloroplast gene sequences and nuclear SSR (simple sequence repeat). The differentiation among island populations, the historical demography, and the underlying evolutionary scenarios of this species are further tested based on the genetic data. Chloroplast diversity reveals a strong genetic divergence between eastern islands (Gran Canaria, Fuerteventura, and Lanzarote) and western islands (EI <span class="hlt">Hierro</span>, La Palma, La Gomera, Tenerife), this west–east genetic divergence may reflect a very beginning of speciation. The evolutionary scenario with highest posterior probabilities suggests Gran Canaria as oldest population with a westward colonization path to Tenerife, La Gomera, La Palma, and EI <span class="hlt">Hierro</span>, and eastward dispersal path to Lanzarote through Fuerteventura. In the western islands, there is a slight decrease in the effective population size toward areas of recent colonization. However, in the eastern islands, the effective population size increase in Lanzarote relative to Gran Canaria and Fuerteventura. These results further our understanding of the evolution of widespread endemic plants within Canarian archipelago. PMID:28713419</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2011JGeo...51..358A','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2011JGeo...51..358A"><span>Verifying the body tide at the Canary Islands using tidal gravimetry observations</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Arnoso, J.; Benavent, M.; Bos, M. S.; Montesinos, F. G.; Vieira, R.</p> <p>2011-05-01</p> <p>Gravity tide records from El <span class="hlt">Hierro</span>, Tenerife and Lanzarote Islands (Canarian Archipelago) have been analyzed and compared to the theoretical body tide model (DDW) of Dehant el al. (1999). The use of more stringent criterion of tidal analysis using VAV program allowed us to reduce the error bars by a factor of two of the gravimetric factors at Tenerife and Lanzarote compared with previous published values. Also, the calibration values have been revisited at those sites. Precise ocean tide loading (OTL) corrections based on up-to-date global ocean models and improved regional ocean model have been obtained for the main tidal harmonics O 1, K 1, M 2, S 2. We also point out the importance of using the most accurate coastline definition for OTL calculations in the Canaries. The remaining observational errors depend on the accuracy of the calibration of the gravimeters and/or on the length of the observed data series. Finally, the comparison of the tidal observations with the theoretical body tide models has been done with an accuracy level of 0.1% at El <span class="hlt">Hierro</span>, 0.4% at Tenerife and 0.5% at Lanzarote.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://rosap.ntl.bts.gov/view/dot/9102','DOTNTL'); return false;" href="https://rosap.ntl.bts.gov/view/dot/9102"><span>Fairfax County and the Commonwealth of Virginia Public Safety and Transportation Operations Center : concept of cooperation (<span class="hlt">Con</span>Coop)</span></a></p> <p><a target="_blank" href="http://ntlsearch.bts.gov/tris/index.do">DOT National Transportation Integrated Search</a></p> <p></p> <p>2005-01-01</p> <p>The Public Safety and Transportation Operations Centers (PSTOCs) Concept of Cooperation (<span class="hlt">Con</span>Coop) enables partner agencies to lay out and reach consensus on: : their intentions in co-locating; : joint functions and systems needed to mee...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://eric.ed.gov/?q=online+AND+education+AND+pros+AND+cons&pg=5&id=EJ601896','ERIC'); return false;" href="https://eric.ed.gov/?q=online+AND+education+AND+pros+AND+cons&pg=5&id=EJ601896"><span>To Bind or Not To Bind: Pros & <span class="hlt">Cons</span> of Maintaining Paper Periodicals in the Library's Collection.</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Anderson, Iris W.</p> <p>1999-01-01</p> <p>Explores controversial questions related to libraries' decision-making on paper journals and electronic journals. Notes that the critical mass of scholarly publishing is still in print. Discusses benefits and drawbacks of electronic journals and paper journals. Presents comments on the pros and <span class="hlt">cons</span> to binding paper periodicals gathered from an…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/servlets/purl/956091','SCIGOV-STC'); return false;" href="https://www.osti.gov/servlets/purl/956091"><span>Pros and <span class="hlt">Cons</span> of the Acceleration Scheme (NF-IDS)</span></a></p> <p><a target="_blank" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a></p> <p>Bogacz, Alex; Bogacz, Slawomir</p> <p></p> <p>The overall goal of the acceleration systems: large acceptance acceleration to 25 GeV and beam shaping can be accomplished by various fixed field accelerators at different stages. They involve three superconducting linacs: a single pass linear Pre-accelerator followed by a pair of multi-pass Recirculating Linear Accelerators (RLA) and finally a nonâ scaling FFAG ring. The present baseline acceleration scenario has been optimized to take maximum advantage of appropriate acceleration scheme at a given stage. Pros and <span class="hlt">cons</span> of various stages are discussed here in detail. The solenoid based Pre-accelerator offers very large acceptance and facilitates correction of energy gain acrossmore » the bunch and significant longitudinal compression trough induced synchrotron motion. However, far off-crest acceleration reduces the effective acceleration gradient and adds complexity through the requirement of individual RF phase control for each cavity. Close proximity of strong solenoids and superc« less</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5639221','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5639221"><span>Pros and <span class="hlt">cons</span> of transcatheter aortic valve implantation (TAVI)</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Terré, Juan A.; George, Isaac</p> <p>2017-01-01</p> <p>Transcatheter aortic valve implantation (TAVI) or replacement (TAVR) was recently approved by the FDA for intermediate risk patients with severe aortic stenosis (AS). This technique was already worldwide adopted for inoperable and high-risk patients. Improved device technology, imaging analysis and operator expertise has reduced the initial worrisome higher complications rate associated with TAVR, making it comparable to surgical aortic valve replacement (SAVR). However, many answers need to be addressed before adoption in lower risk patients. This paper highlights the pros and <span class="hlt">cons</span> of TAVI based mostly on randomized clinical trials involving the two device platforms approved in the United States. We focused our analysis on metrics that will play a key role in expanding TAVR indication in healthier individuals. We review the significance and gave a perspective on paravalvular leak (PVL), valve performance, valve durability, leaflet thrombosis, stroke and pacemaker requirement. PMID:29062739</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014AGUFMEP21D3566G','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014AGUFMEP21D3566G"><span>U-Pb Detrital Zircon Geochronologic Constraints on Depositional Age and Sediment Source Terrains of the Late Paleozoic Tepuel-Genoa Basin</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Griffis, N. P.; Montanez, I. P.; Isbell, J.; Gulbranson, E. L.; Wimpenny, J.; Yin, Q. Z.; Cúneo, N. R.; Pagani, M. A.; Taboada, A. C.</p> <p>2014-12-01</p> <p>The late Paleozoic Ice Age (LPIA) is the longest-lived icehouse of the Phanerozoic and the only time a metazoan dominated and vegetated world transitioned from an icehouse climate into a greenhouse. Despite several decades of research, the timing, extent of glaciation and the location of ice centers remain unresolved, which prohibits reconstruction of ice volume. The Permo-Carboniferous sediments in the Tepuel-Genoa Basin, Patagonia contains a near complete record of sedimentation from the lower Carboniferous through lower Permian. Outsized clasts, thin pebble-rich diamictites and slumps represent the last of the late Paleozoic glacially influenced deep-water marine sediments in the Mojón de <span class="hlt">Hierro</span> Fm. and the Paleozoic of Patagonia. U-Pb analysis of detrital zircons separated from slope sediments reveal groupings (20 myr bins, n≥5 zircons) with peak depositional ages of 420, 540 to 660 and 1040 Ma. Zircon age populations recovered from the Mojón de <span class="hlt">Hierro</span> Fm. compare well with bedrock ages of the Deseado Massif of SE Patagonia, suggesting this may be a potential source of sediments. The maximum depositional age of the sediments is 306.05 ± 3.7 Ma (2σ) as determined by the median age of the two youngest concordant zircons that overlap in error. The youngest zircon from the analysis yields a 238U/206Pb age of 301.3 ± 4.5 Ma (2σ; MSWD = 2.3). Younger zircons from the analysis compare well with the age of granite bedrock exposed along the basin margin to the E-NE suggesting they may reflect a more proximal source. These data, which indicate a maximum age of late Carboniferous for the Mojón de <span class="hlt">Hierro</span> Fm, provide the first geochemical constraints for the timing of final deposition of glaciomarine sediments in the Tepuel-Genoa Basin, and contributes to the biostratigraphic correlation of the late Paleozoic succession in Patagonia with other key LPIA basins that has thus far been hindered by faunal provincialism.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/17149039','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/17149039"><span>Pros and <span class="hlt">cons</span> of healthcare information technology implementation: the pros win.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Maffei, Roxana</p> <p>2006-01-01</p> <p>Countless studies and investigations have been performed siding either for or against the implementation of technology in the healthcare setting. This article presents both sides of this debate, with an obvious conclusion that the pros of this debate win. The practice of information technology in the medical domain lags behind its knowledge and discovery by at least 7 years. The key to closing this gap is to show, through various studies, how information technology systems provide decision support to users at the point in time when decisions are needed. What the reader will obtain from this article is that the pros for information technology implementation in healthcare settings weigh much more and have a greater effect than the <span class="hlt">cons</span>.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5296246','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5296246"><span>The <span class="hlt">Con</span>NECT Framework: a model for advancing behavioral medicine science and practice to foster health equity</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Alcaraz, Kassandra I.; Sly, Jamilia; Ashing, Kimlin; Fleisher, Linda; Gil-Rivas, Virginia; Ford, Sabrina; Yi, Jean C.; Lu, Qian; Meade, Cathy D.; Menon, Usha; Gwede, Clement K.</p> <p>2017-01-01</p> <p>Health disparities persist despite ongoing efforts. Given the United States’ rapidly changing demography and socio-cultural diversity, a paradigm shift in behavioral medicine is needed to advance research and interventions focused on health equity. This paper introduces the <span class="hlt">Con</span>-NECT Framework as a model to link the sciences of behavioral medicine and health equity with the goal of achieving equitable health and outcomes in the twenty-first century. We first evaluate the state of health equity efforts in behavioral medicine science and identify key opportunities to advance the field. We then discuss and present actionable recommendations related to <span class="hlt">Con</span>NECT’s five broad and synergistic principles: (1) Integrating Context; (2) Fostering a Norm of Inclusion; (3) Ensuring Equitable Diffusion of Innovations; (4) Harnessing Communication Technology; and (5) Prioritizing Specialized Training. The framework holds significant promise for furthering health equity and ushering in a new and refreshing era of behavioral medicine science and practice. PMID:27509892</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27509892','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27509892"><span>The <span class="hlt">Con</span>NECT Framework: a model for advancing behavioral medicine science and practice to foster health equity.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Alcaraz, Kassandra I; Sly, Jamilia; Ashing, Kimlin; Fleisher, Linda; Gil-Rivas, Virginia; Ford, Sabrina; Yi, Jean C; Lu, Qian; Meade, Cathy D; Menon, Usha; Gwede, Clement K</p> <p>2017-02-01</p> <p>Health disparities persist despite ongoing efforts. Given the United States' rapidly changing demography and socio-cultural diversity, a paradigm shift in behavioral medicine is needed to advance research and interventions focused on health equity. This paper introduces the <span class="hlt">Con</span>NECT Framework as a model to link the sciences of behavioral medicine and health equity with the goal of achieving equitable health and outcomes in the twenty-first century. We first evaluate the state of health equity efforts in behavioral medicine science and identify key opportunities to advance the field. We then discuss and present actionable recommendations related to <span class="hlt">Con</span>NECT's five broad and synergistic principles: (1) Integrating Context; (2) Fostering a Norm of Inclusion; (3) Ensuring Equitable Diffusion of Innovations; (4) Harnessing Communication Technology; and (5) Prioritizing Specialized Training. The framework holds significant promise for furthering health equity and ushering in a new and refreshing era of behavioral medicine science and practice.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3596329','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3596329"><span>The Protective Effect of Intrasplenic Transplantation of Ad-IL-18BP/IL-4 Gene-Modified Fetal Hepatocytes on <span class="hlt">Con</span>A-Induced Hepatitis in Mice</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Xu, Chenhuai; Hong, Bo; Xu, Wanhong; Shen, Ling; Jin, Changzhong; Wu, Zhigang; Tong, Xiangmin; Yao, Hangping</p> <p>2013-01-01</p> <p>Background Concanavalin A (<span class="hlt">Con</span>A)-induced hepatitis is an experimental murine model mirroring the pathology of human autoimmune hepatitis. Aim To investigate the effects of intrasplenically transplanted fetal hepatocytes (BNL.CL2) transfected with recombinant adenovirus vector expressing the IL-18 binding protein (IL-18BP) and IL-4 fusion protein on <span class="hlt">Con</span>A-induced hepatitis in mice. Methods Ad-IL-18BP/IL-4 was used to infect BNL.CL2 cells. IL-4 and IL-18BP fusion protein expression were detected by ELISA and Western blotting. BNL.CL2 cells infected with Ad-IL-18BP/IL-4 were intrasplenically transplanted into mice. After 10 days, mice were injected with <span class="hlt">Con</span>A (15 mg/kg), and sacrificed 18 hours later. Liver injury was assessed by serum transaminase and liver histology. TNF-α, IL-18, IL-4, IL-10, IL-12p70 and monocyte-chemoattracting protein (MCP)-1 levels in serum and liver homogenates were detected by ELISA. Signaling molecules in liver homogenates were analyzed by Western blotting. Results Ad-IL-18BP/IL-4 effectively expressed the IL-18BP/IL-4 fusion protein for more than 14 days in BNL.CL12 cells. Treatment of mice with Ad-IL-18BP/IL-4-BNL.CL2 before <span class="hlt">Con</span>A injection significantly reduced the elevated plasma levels of transaminases compared with <span class="hlt">Con</span>A control groups. TNF-α, IL-18, IL-12p70 and MCP-1 levels in serum and liver homogenates from mice transplanted with Ad-IL-18BP/IL-4-BNL.CL2 were lower and IL-4 and IL-10 levels were higher than control groups. Phosphorylation levels of NF-κB p65, AKT, p38 and JNK1/2 in liver homogenates were markedly suppressed by Ad-IL-18BP/IL-4. Conclusions Ad-IL-18BP/IL-4 was effectively transfected into mouse BNL.CL2 cells. Intrasplenic transplantation of Ad-IL-18BP/IL-4-BNL.CL12 cells alleviated the severity of inflammation in <span class="hlt">Con</span>A-induced experimental hepatitis and provides a useful basis for the targeted gene therapy of liver disease. PMID:23516562</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/23516562','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/23516562"><span>The protective effect of intrasplenic transplantation of Ad-IL-18BP/IL-4 gene-modified fetal hepatocytes on <span class="hlt">Con</span>A-induced hepatitis in mice.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Shao, Xueting; Qian, Yun; Xu, Chenhuai; Hong, Bo; Xu, Wanhong; Shen, Ling; Jin, Changzhong; Wu, Zhigang; Tong, Xiangmin; Yao, Hangping</p> <p>2013-01-01</p> <p>Concanavalin A (<span class="hlt">Con</span>A)-induced hepatitis is an experimental murine model mirroring the pathology of human autoimmune hepatitis. To investigate the effects of intrasplenically transplanted fetal hepatocytes (BNL.CL2) transfected with recombinant adenovirus vector expressing the IL-18 binding protein (IL-18BP) and IL-4 fusion protein on <span class="hlt">Con</span>A-induced hepatitis in mice. Ad-IL-18BP/IL-4 was used to infect BNL.CL2 cells. IL-4 and IL-18BP fusion protein expression were detected by ELISA and Western blotting. BNL.CL2 cells infected with Ad-IL-18BP/IL-4 were intrasplenically transplanted into mice. After 10 days, mice were injected with <span class="hlt">Con</span>A (15 mg/kg), and sacrificed 18 hours later. Liver injury was assessed by serum transaminase and liver histology. TNF-α, IL-18, IL-4, IL-10, IL-12p70 and monocyte-chemoattracting protein (MCP)-1 levels in serum and liver homogenates were detected by ELISA. Signaling molecules in liver homogenates were analyzed by Western blotting. Ad-IL-18BP/IL-4 effectively expressed the IL-18BP/IL-4 fusion protein for more than 14 days in BNL.CL12 cells. Treatment of mice with Ad-IL-18BP/IL-4-BNL.CL2 before <span class="hlt">Con</span>A injection significantly reduced the elevated plasma levels of transaminases compared with <span class="hlt">Con</span>A control groups. TNF-α, IL-18, IL-12p70 and MCP-1 levels in serum and liver homogenates from mice transplanted with Ad-IL-18BP/IL-4-BNL.CL2 were lower and IL-4 and IL-10 levels were higher than control groups. Phosphorylation levels of NF-κB p65, AKT, p38 and JNK1/2 in liver homogenates were markedly suppressed by Ad-IL-18BP/IL-4. Ad-IL-18BP/IL-4 was effectively transfected into mouse BNL.CL2 cells. Intrasplenic transplantation of Ad-IL-18BP/IL-4-BNL.CL12 cells alleviated the severity of inflammation in <span class="hlt">Con</span>A-induced experimental hepatitis and provides a useful basis for the targeted gene therapy of liver disease.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2011PhDT.......360M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2011PhDT.......360M"><span>Nanoparticulas basadas en complejos de Fe(II) <span class="hlt">con</span> transicion de espin: sintesis, caracterizacion y aplicaciones en electronica molecular</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Monrabal Capilla, Maria</p> <p></p> <p>Esta tesis doctoral esta organizada en 5 capitulos y esta destinada al estudio de sistemas de Fe (II) que presentan el fenomeno de la transicion de espin a escala nanometrica. El capitulo 1 contiene una introduccion general sobre materiales moleculares multifuncionales, destacando aquellos ejemplos mas importantes. Por otro lado, se explicara el fenomeno de la transicion de espin, tratando aspectos conceptuales, los antecedentes mas importantes y la situacion actual. En el capitulo 2 se describen los diferentes procesos existentes para la obtencion de diferentes tipos de nanoparticulas. Ademas, se presenta la sintesis y caracterizacion de nanoparticulas del polimero de coordinacion unidimensional [Fe(Htrz)2(trz)]BF4, obtenidas mediante el metodo de micelas inversas. Estas nanoparticulas, <span class="hlt">con</span> una estrecha distribucion de tamanos centrada alrededor de los 11 nm, presentan una transicion de espin muy abrupta, <span class="hlt">con</span> un ancho ciclo de histeresis termica de unos 40K. En el capitulo 3 se describe el proceso de modificacion del tamano de las nanoparticulas descritas en el capitulo anterior, llevado a cabo variando la proporcion de surfactante/H2O en el medio. Ademas, <span class="hlt">con</span> el objetivo de modificar las propiedades magneticas de las nanoparticulas obtenidas en el capitulo 2, se lleva a cabo la sintesis de nanoparticulas de polimeros de la misma familia del [Fe(Htrz)2(trz)]BF4. En concreto se sintetizaron 3 nuevos tipos de nanoparticulas basadas en el polimero [Fe(Htrz)1-x(NH2trz)x](ClO4)2, siendo x = 0.05, 0.15 y 0.3, en cada caso. Estas nanoparticulas siguen presentando una estrecha distribucion de tamanos y una transicion de espin muy abrupta y <span class="hlt">con</span> un ancho ciclo de histeresis. Ademas, se observa que este ciclo se desplaza a temperaturas mas proximas a la temperatura ambiente a medida que se aumenta el porcentaje de 4-amino-1, 2, 4- triazol en la muestra. Pero al mismo tiempo se produce una disminucion de la anchura de este ciclo. Por ultimo, en este capitulo se presenta la</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25927294','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25927294"><span>Establishing confidence in the output of qualitative research synthesis: the <span class="hlt">Con</span>Qual approach.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Munn, Zachary; Porritt, Kylie; Lockwood, Craig; Aromataris, Edoardo; Pearson, Alan</p> <p>2014-09-20</p> <p>The importance of findings derived from syntheses of qualitative research has been increasingly acknowledged. Findings that arise from qualitative syntheses inform questions of practice and policy in their own right and are commonly used to complement findings from quantitative research syntheses. The GRADE approach has been widely adopted by international organisations to rate the quality and confidence of the findings of quantitative systematic reviews. To date, there has been no widely accepted corresponding approach to assist health care professionals and policy makers in establishing confidence in the synthesised findings of qualitative systematic reviews. A methodological group was formed develop a process to assess the confidence in synthesised qualitative research findings and develop a Summary of Findings tables for meta-aggregative qualitative systematic reviews. Dependability and credibility are two elements considered by the methodological group to influence the confidence of qualitative synthesised findings. A set of critical appraisal questions are proposed to establish dependability, whilst credibility can be ranked according to the goodness of fit between the author's interpretation and the original data. By following the processes outlined in this article, an overall ranking can be assigned to rate the confidence of synthesised qualitative findings, a system we have labelled <span class="hlt">Con</span>Qual. The development and use of the <span class="hlt">Con</span>Qual approach will assist users of qualitative systematic reviews to establish confidence in the evidence produced in these types of reviews and can serve as a practical tool to assist in decision making.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28149839','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28149839"><span>Soy-Based Therapeutic Baby Formulas: Testable Hypotheses Regarding the Pros and <span class="hlt">Cons</span>.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Westmark, Cara J</p> <p>2016-01-01</p> <p>Soy-based infant formulas have been consumed in the United States since 1909, and currently constitute a significant portion of the infant formula market. There are efforts underway to generate genetically modified soybeans that produce therapeutic agents of interest with the intent to deliver those agents in a soy-based infant formula platform. The threefold purpose of this review article is to first discuss the pros and <span class="hlt">cons</span> of soy-based infant formulas, then present testable hypotheses to discern the suitability of a soy platform for drug delivery in babies, and finally start a discussion to inform public policy on this important area of infant nutrition.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5241282','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5241282"><span>Soy-Based Therapeutic Baby Formulas: Testable Hypotheses Regarding the Pros and <span class="hlt">Cons</span></span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Westmark, Cara J.</p> <p>2017-01-01</p> <p>Soy-based infant formulas have been consumed in the United States since 1909, and currently constitute a significant portion of the infant formula market. There are efforts underway to generate genetically modified soybeans that produce therapeutic agents of interest with the intent to deliver those agents in a soy-based infant formula platform. The threefold purpose of this review article is to first discuss the pros and <span class="hlt">cons</span> of soy-based infant formulas, then present testable hypotheses to discern the suitability of a soy platform for drug delivery in babies, and finally start a discussion to inform public policy on this important area of infant nutrition. PMID:28149839</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li class="active"><span>16</span></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_16 --> <div id="page_17" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li class="active"><span>17</span></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="321"> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA598664','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA598664"><span>Population Parameters of Blainville’s and Cuvier’s Beaked Whales</span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>2013-09-30</p> <p><span class="hlt">Hierro</span>. May 2013-2014. ULL. Current. Phil Hammond • Harbour seal diet around Scotland: evidence for competition with grey seals (Scottish...in three meetings and conferences: Aguilar de Soto, N. et al. 2013. From the Canary Islands sucess to the Mediterranean : Areas of Special Concern...Setubal (Portugal) Aguilar de Soto, N. (2012) Proposal of inclusion in Annex I CMS: Mediterranean subpopulation of Cuvier´s beaked whale Ziphius</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014era..conf50301H','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014era..conf50301H"><span>CHILES <span class="hlt">Con</span> Pol: Probing galaxy evolution, the dark Universe, and cosmic magnetism with a deep 1000 hour Jansky VLA survey</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Hales, Christopher A.; Chiles Con Pol Collaboration</p> <p>2014-04-01</p> <p>We recently started a 1000 hour campaign to observe 0.2 square degrees of the COSMOS field in full polarization continuum at 1.4 GHz with the Jansky VLA, as part of a joint program with the spectral line COSMOS HI Large Extragalactic Survey (CHILES). When complete, we expect our CHILES Continuum Polarization (CHILES <span class="hlt">Con</span> Pol) survey to reach an unprecedented SKA-era sensitivity of 0.7 uJy per 4 arcsecond FWHM beam. Here we present the key goals of CHILES <span class="hlt">Con</span> Pol, which are to (i) produce a source catalog of legacy value to the astronomical community, (ii) measure differential source counts in total intensity, linear polarization, and circular polarization in order to constrain the redshift and luminosity distributions of source populations, (iii) perform a novel weak lensing study using radio polarization as an indicator of intrinsic alignment to better study dark energy and dark matter, and (iv) probe the unknown origin of cosmic magnetism by measuring the strength and structure of intergalactic magnetic fields in the filaments of large scale structure. The CHILES <span class="hlt">Con</span> Pol source catalog will be a useful resource for upcoming wide-field surveys by acting as a training set for machine learning algorithms, which can then be used to identify and classify radio sources in regions lacking deep multiwavelength coverage.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/20140000580','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/20140000580"><span>Flight Deck Surface Trajectory-based Operations (STBO): Results of Piloted Simulations and Implications for Concepts of Operation (<span class="hlt">Con</span>Ops)</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Foyle, David C.; Hooey, Becky L.; Bakowski, Deborah L.</p> <p>2013-01-01</p> <p>The results offour piloted medium-fidelity simulations investigating flight deck surface trajectory-based operations (STBO) will be reviewed. In these flight deck STBO simulations, commercial transport pilots were given taxi clearances with time and/or speed components and required to taxi to the departing runway or an intermediate traffic intersection. Under a variety of concept of operations (<span class="hlt">Con</span>Ops) and flight deck information conditions, pilots' ability to taxi in compliance with the required time of arrival (RTA) at the designated airport location was measured. <span class="hlt">Con</span>Ops and flight deck information conditions explored included: Availability of taxi clearance speed and elapsed time information; Intermediate RTAs at intermediate time constraint points (e.g., intersection traffic flow points); STBO taxi clearances via ATC voice speed commands or datal ink; and, Availability of flight deck display algorithms to reduce STBO RTA error. Flight Deck Implications. Pilot RTA conformance for STBO clearances, in the form of ATC taxi clearances with associated speed requirements, was found to be relatively poor, unless the pilot is required to follow a precise speed and acceleration/deceleration profile. However, following such a precise speed profile results in inordinate head-down tracking of current ground speed, leading to potentially unsafe operations. Mitigating these results, and providing good taxi RTA performance without the associated safety issues, is a flight deck avionics or electronic flight bag (EFB) solution. Such a solution enables pilots to meet the taxi route RTA without moment-by-moment tracking of ground speed. An avionics or EFB "error-nulling" algorithm allows the pilot to view the STBO information when the pilot determines it is necessary and when workload alloys, thus enabling the pilot to spread his/her attention appropriately and strategically on aircraft separation airport navigation, and the many other flight deck tasks concurrently required</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/6854015','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/6854015"><span>Ontogeny of <span class="hlt">con</span> A and PHA responses of chicken blood cells in MHC-compatible lines 6(3) and 7(2).</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Fredericksen, T L; Gilmour, D G</p> <p>1983-06-01</p> <p>The development of T cell responsiveness to <span class="hlt">Con</span> A and PHA was examined in two MHC-compatible inbred chicken lines, RPRL 6(3) and 7(2), at ages 2 to 118 days posthatching. These lines are respectively resistant or susceptible to Marek's disease, a naturally occurring, virally induced T cell lymphoma. Between-line comparisons were made of optimal in vitro responses of diluted serum-free blood cells to each mitogen in two groups of chicks tested over ages 2 to 63 and 41 to 118 days. Over 2 to 63 days, <span class="hlt">Con</span> A responses increased with age at the same rate in each line, but 7(2) responses averaged 2.3 times higher than 6(3). The increase with age was dependent on blood lymphocyte counts, which also increased with age in parallel in both lines. In contrast, the between-line difference in responsiveness was dependent on intrinsic reactivity of cells as well as lymphocyte counts. Covariance analysis was used to estimate that line 7(2) was 1.4 times higher than 6(3) in intrinsic cell reactivity, after accounting for the effect of the twofold higher blood lymphocyte counts in 7(2), and that this intrinsic difference contributed almost one-half the total difference. Over 41 to 118 days <span class="hlt">Con</span> A responses no longer increased with age, although lymphocyte counts were still increasing, and the line difference (2.6 times) was now almost entirely contributed by a 2.3-fold superiority of 7(2) blood cells in intrinsic reactivity. The line difference in PHA responses was the reverse of the above in young chicks, with 6(3) responses greater than 7(2) in spite of lower lymphocyte counts. In additional chicks tested over 5 to 26 days, intrinsic reactivity of 6(3) cells to PHA averaged 4.5 times higher than 7(2). There was an abrupt decline in intrinsic reactivity of line 6(3) blood cells between 26 and 41 days to a level equal with 7(2). After this age, line 7(2) responses were 1.8 times greater than those of 6(3), and this difference was dependent solely on lymphocyte count differences. The</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/10219211','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/10219211"><span>The Inter<span class="hlt">Con</span> network: a program for education partnerships at the University of Texas-Houston Health Science Center.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Castro, G A; Bouldin, P A; Farver, D W; Maugans, L A; Sanders, L C; Booker, J</p> <p>1999-04-01</p> <p>The University of Texas-Houston Health Science Center (UT-Houston) has created programs and activities to address the state's pressing needs in minority education. Through Inter<span class="hlt">Con</span>, a network of universities and K-12 schools, UT-Houston works with its partners to identify competitive candidates in the current pool of minority graduates with bachelor's degrees and to help them--along with their non-minority counterparts--progress in their education. Another objective is to expand the pool of minorities underrepresented in medicine who complete high school and go to college. In 1994 UT-Houston and Prairie View A&M University created a collaborative venture to provide new educational opportunities at UT-Houston for Prairie View's predominantly African American students. A three-track summer internship program--a result of that collaboration--has since been expanded to partnerships with other minority and majority universities throughout Texas. In 1998, for example, 108 undergraduate students from these universities (and 40 other universities nationwide) participated in research, professional, and administrative summer internships at UT-Houston. The Inter<span class="hlt">Con</span> network also has partnerships with K-12 schools. UT-Houston works with inner-city, suburban, and rural school districts to develop education models that can be transferred throughout the state. The partnerships deal with helping to teach basic academic skills and computer literacy, improve science-related instruction, meet demands for health promotion materials and information for school-initiated health and wellness programs, and develop distance-learning paradigms. UT-Houston views Inter<span class="hlt">Con</span> as a program helping Texas institutions to engage and adapt to the socioeconomic factors, demographic changes, and technology explosion that currently challenge public education.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014PhDT.......343M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014PhDT.......343M"><span>"Estudio tribologico de aceros para moldes. Aplicacion al moldeo por inyeccion de polibutilentereftalato reforzado <span class="hlt">con</span> fibra de vidrio"</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Martinez Mateo, Isidoro Jose</p> <p></p> <p> fabricacion del molde, tienen una gran influencia sobre su comportamiento en servicio a lo largo de la vida util del molde. En la primera parte del presente estudio, a partir de ensayos punzon sobre disco, se ha determinado la relacion entre la resistencia al desgaste y la dureza de aceros para moldes obtenidos a partir de bloques de gran espesor, estudiando los principales mecanismos de desgaste que tienen lugar. A continuacion, <span class="hlt">con</span> el fin de determinar el dano superficial que sufren los aceros para moldes en condiciones reales de inyeccion, se han estudiado distintos tipos de aceros utilizados comercialmente en moldes de inyeccion de polimeros y materiales compuestos, seleccionando las condiciones de operacion para determinar la variacion de la rugosidad superficial del acero en funcion del material inyectado, del numero de operaciones sucesivas de inyeccion y de la orientacion del flujo de inyeccion, mediante tecnicas de perfilometria optica y microscopia electronica de barrido. Ademas del dano superficial sufrido por el acero <span class="hlt">con</span> el numero de piezas inyectadas, tambien se ha determinado la evolucion de la rugosidad superficial de los materiales inyectados, polibutilentereftalato (PBT) puro y materiales compuestos derivados de PBT por adicion de un 20 o un 50% en peso de fibra de vidrio. En el caso de las piezas inyectadas, se ha caracterizado su microestructura en funcion del flujo de inyeccion y de la densidad de fibra, se han determinado sus propiedades termicas y dinamico-mecanicas, asi como la variacion de la rugosidad superficial de las piezas inyectadas <span class="hlt">con</span> el numero de operaciones de inyeccion y <span class="hlt">con</span> la geometria de las distintas secciones de las piezas. Finalmente, se ha evaluado la resistencia a la abrasion de PBT reforzado <span class="hlt">con</span> un 50% de fibra, en funcion del numero de piezas inyectadas y de la direccion de rayado <span class="hlt">con</span> respecto a la orientacion del flujo de inyeccion.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/9523519','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/9523519"><span>Laparoscopy for inflammatory bowel disease: pros and <span class="hlt">cons</span>.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Sardinha, T C; Wexner, S D</p> <p>1998-04-01</p> <p>The role of laparoscopic surgery in the treatment of colorectal malignancies is still under investigation, although it can offer significant benefits to many patients with inflammatory bowel disease (IBD). The aim of this study was to assess the pros and <span class="hlt">cons</span> of the laparoscopic management of IBD. Data were obtained from a review of the literature published since 1992, when the first report of laparoscopic surgery for IBD appeared in print. From 1992 to 1997 several series of laparoscopic colorectal surgery for the management of IBD have been reported. A close evaluation of these studies revealed that laparoscopy in patients with terminal ileal Crohn's disease or anal Crohn's disease in need of fecal diversion offers significant advantages compared to laparotomy, including decreased pain, length of hospitalization, and disability. An additional bonus is improved cosmesis and a reduction in symptomatic postoperative adhesions. These many benefits can be achieved without any increase in morbidity or expense. Conversely, the use of this technology for restorative proctocolectomy in patients with mucosal ulcerative colitis is associated with a longer operative time and an increased incidence of both intra- and postoperative complications compared to laparotomy. Laparoscopic colorectal surgery can thus be advantageous for treatment of terminal ileal Crohn's disease but cannot be routinely justified for the treatment of mucosal ulcerative colitis.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3011817','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3011817"><span>Uso de Sustancias en Mujeres <span class="hlt">con</span> Desventaja Social: Riesgo para el Contagio de VIH/SIDA</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Cianelli, R.; Ferrer, L; Bernales, M.; Miner, S.; Irarrázabal, L.; Molina, Y.</p> <p>2009-01-01</p> <p>Antecedentes La caracterización epidemiológica en Chile apunta a feminización, pauperización y heterosexualización de la epidemia del VIH, lo que implica un mayor riesgo para las mujeres en desventaja social. Si a esto se suma la utilización de sustancias, la vulnerabilidad de este grupo frente al VIH/SIDA aumenta. Objetivo Describir el uso de sustancias en mujeres <span class="hlt">con</span> desventaja social e identificar factores de riesgo de contagio de VIH, asociados a este consumo. Material y Método 52 mujeres fueron entrevistadas como parte del proyecto “Testeando una intervención en prevención de VIH/SIDA en mujeres chilenas” GRANT # RO1 TW 006977. Se describen variables sociodemográficas y de consumo de sustancias a través de estadísticas descriptivas y se analiza la relación entre variables a través de pruebas de correlación. Resultados Los resultados indican un perfil sociodemográfico que sitúa a las mujeres en situación de vulnerabilidad frente al contagio de VIH/SIDA, <span class="hlt">con</span> alto índice de uso de sustancias que acentúa el riesgo. Conclusiones Los hallazgos apuntan a la necesidad de considerar intervenciones que se enfoquen en la prevención de VIH en mujeres, abordando los riesgos asociados al consumo de sustancias. PMID:21197380</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1998BAAA...42...69D','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1998BAAA...42...69D"><span>Medición de placas astrométricas obtenidas <span class="hlt">con</span> el telescopio Astrográfico de La Plata</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>di Sisto, R. P.; Orellana, R.</p> <p></p> <p>El Observatorio de La Plata cuenta <span class="hlt">con</span> un gran número de placas de asteroides y cometas obtenidas <span class="hlt">con</span> el telescopio astrográfico, que cubren gran parte del cielo del hemisferio sur. En 1996 se recopilaron y clasificaron 2187 placas (Beca para estudiantes de la AAA 1996) de las cuales 2031 corresponden a asteroides. Los datos de cada placa se volcaron en una base de datos creada para facilitar su manejo y preservar la información. A partir de este trabajo se revisaron los MPC electrónicos y se identificaron aquellas placas de asteroides pertenecientes a nuestra base de datos cuyos resultados no fueron publicados en los mismos. De un total de 400 placas que no aparecían publicadas sobresalía un paquete constituído por 40 placas obtenidas en 1977. Estas últimas fueron reducidas utilizando las posiciones y movimientos propios de las estrellas de referencia obtenidas del catálogo SAO 2000 dadas para el sistema FK5. Las posiciones calculadas fueron enviadas y publicadas en los Minor Planet Circulars (MPC).</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2003BAAA...46..117L','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2003BAAA...46..117L"><span>Violación del Principio de Equivalencia en Teorías <span class="hlt">con</span> Dilatón de Cuerdas</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Landau, S. J.; Sisterna, P. D.; Vucetich, H.</p> <p></p> <p>Se estudian las violaciones al Principio de Equivalencia en Teorías <span class="hlt">con</span> Dilatón de Cuerdas. En estos modelos, algunas de las constantes fundamentales dependen del espacio y del tiempo. Se muestra que los experimentos de caída libre no tienen aún precisión como para poner límites a los parámetros de la teoría.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25264397','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25264397"><span>Presentación del estudio "Links" de hombres que tienes sexo <span class="hlt">con</span> hombres en Buenos Aires, Argentina.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Carballo-Diéguez, Alex; Avila, María M; Balán, Iván C; Marone, Rubén; Pando, María A; Barreda, Victoria</p> <p>2011-03-01</p> <p>Estudios previos en Buenos Aires reportaron altas prevalencias de HIV entre HSH, <span class="hlt">con</span> valores que oscilan entre 9 y 14% durante casi 10 años de continuo testeo. El objetivo principal de este estudio fue la evaluación de factores relacionados al comportamiento de alto riesgo para transmisión del HIV entre HSH entre los que se incluyen el conocimiento y factores emocionales, socioculturales y ambientales. Por otro lado se realizó la estimación de prevalencia e incidencia de HIV utilizando RDS (Respondent Driven Sampling), así como la presencia de otras infecciones de transmisión sexual. Por último se evaluaron los hábitos de testeo para HIV indagando que factores facilitan o impiden su realización. El estudio constó de dos fases, en primer lugar una fase cualitativa y posteriormente una fase cuantitativa <span class="hlt">con</span> una duración total de 4 años y medio. Durante la fase cualitativa se realizaron 44 entrevistas individuales en profundidad, 8 grupos focales y 10 observaciones etnográficas (hoteles, baños públicos ("teteras"), cines pornográficos, fiestas privadas, dark rooms y discotecas). Durante la fase cuantitativa del estudio se realizó el reclutamiento de 500 participantes que provinieron de la Ciudad Autónoma de Buenos Aires, así como del Gran Buenos Aires. El reclutamiento se comenzó <span class="hlt">con</span> 16 participantes llamados semillas. Se realizó el diagnóstico de infección por HIV, hepatitis B y C (HBV y HCV), Treponema pallidum, Virus Papiloma Humano (HPV) y Chlamidias. La colaboración establecida entre los grupos de trabajo enfocados en áreas diversas posibilitó el abordaje conjunto de nuevas estrategias de investigación antes no exploradas en nuestro país. Los resultados más relevantes de esta investigación serán progresivamente publicados en sucesivos números de Actualizaciones en SIDA.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016AGUFMOS41C1987S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016AGUFMOS41C1987S"><span>Combination of ORP and pH sensors in tow-yo studies to map redox and acid-base anomalies in seawater due to hydrothermal activity in shallow areas</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Santana-Casiano, J. M.; González-Dávila, M.; Fraile-Nuez, E.; Santana-González, C.; Baker, E. T.; Resing, J. A.; Walker, S. L.</p> <p>2016-12-01</p> <p>The detection of activity from low-temperature hydrothermal vents, where the increase in temperature is not evident, requires the utilization of alternative sensors that respond to emissions of certain chemical species. The character of both reduced and acid fluids in the volcanic emissions in the El <span class="hlt">Hierro</span> submarine volcano allowed us to detect anomalies related with changes in the chemical potential and the proton concentration using ORP and pH sensors, respectively. Tow-yos with these sensors provided the approximate locations of the emissions plotting δ(ORP)/δt and ΔpH versus the latitude or longitude. The ORP sensor responds very quickly to the presence of reduced chemicals in the water column. The magnitude of this change is examined by the time derivative of ORP, δ(ORP)/δt. For pH changes, ΔpH, the mean pH for each depth at a reference station in an area not affected by the vent emission is subtracted from each point measured near the volcanic edifice. The submarine volcano of El <span class="hlt">Hierro</span>, in its degasification stage, provided an excellent opportunity to apply CTD-pH-ORP tow-yo methodology and to study the effect of CO2 emission on the seawater carbonate system, the global carbon flux, and local ocean acidification. Detailed surveys of the volcanic edifice were carried out during VULCANO 0314 and VULCANA0615 cruises using several CTD-pH-ORP tow-yo studies, localizing the redox and acidic changes, which were used to obtain surface maps of anomalies. CTD-pH-ORP yo-yo studies were also conducted that included discrete sampling for carbonate system parameters and total dissolved Fe(II), TDFe(II). The inputs of CO2 along multiple sections combined with measurements of oceanic currents produced an estimated volcanic CO2 flux = 6.0 105 ± 1.1 105 kg d-1and increases the acidity above the volcano by 20%. From the yo-yo studies important anomalies in both pHT and TDFe(II) were observed. The increased TDFe(II) concentrations and the low associated pHT values may</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29549787','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29549787"><span>Identification of nucleotides in the 5'UTR and amino acids substitutions that are essential for the infectivity of 5'UTR-NS5A recombinant of hepatitis C virus genotype 1b (strain <span class="hlt">Con</span>1).</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Li, Jinqian; Feng, Shengjun; Liu, Xi; Guo, Mingzhe; Chen, Mingxiao; Chen, Yiyi; Rong, Liang; Xia, Jinyu; Zhou, Yuanping; Zhong, Jin; Li, Yi-Ping</p> <p>2018-05-01</p> <p>Genotype 1b strain <span class="hlt">Con</span>1 represents an important reference in the study of hepatitis C virus (HCV). Here, we aimed to develop an advanced infectious <span class="hlt">Con</span>1 recombinant. We found that previously identified mutations A1226G/F1464L/A1672S/Q1773H permitted culture adaption of <span class="hlt">Con</span>1 Core-NS5A (C-5A) recombinant containing 5'UTR and NS5B-3'UTR from JFH1 (genotype 2a), thus acquired additional mutations L725H/F886L/D2415G. C-5A containing all seven mutations (C-5A_7m) replicated efficiently in Huh7.5 and Huh7.5.1 cells and had an increased infectivity in SEC14L2-expressing Huh7.5.1 cells. Incorporation of <span class="hlt">Con</span>1 NS5B was deleterious to C-5A_7m, however <span class="hlt">Con</span>1 5'UTR was permissive but attenuated the virus. Nucleotides G1, A4, and G35 primarily accounted for the viral attenuation without affecting RNA translation. C-5A_7m was inhibited dose-dependently by simeprevir and daclatasvir, and substitutions at A4, A29, A34, and G35 conferred resistance to miR-122 antagonism. The novel <span class="hlt">Con</span>1 5'UTR-NS5A recombinant, adaptive mutations, and critical nucleotides described here will facilitate future studies of HCV culture systems and virus-host interaction. Copyright © 2018 Elsevier Inc. All rights reserved.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=STS030-73-087&hterms=hierro&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D60%26Ntt%3Dhierro','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=STS030-73-087&hterms=hierro&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D60%26Ntt%3Dhierro"><span>Canary Island Archipelago</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p></p> <p>1989-01-01</p> <p>This nearly vertical view of the Canary Archipelago (28.5N, 16.5W) shows five of the seven islands: Grand Canary, Tenerife, Gomera, <span class="hlt">Hierro</span> and La Palma. The largest island in view is Tenerife. Island cloud wakes evident in this photo are the result of southerly winds giving rise to cloud banks on the lee side especially on Tenerife which has the highest volcanic peaks. Island water wakes and internal waves are also evident but not as apparent.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/21404264','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/21404264"><span>Preparation of stimulus responsive multiple emulsions by membrane emulsification using <span class="hlt">con</span> a as biochemical sensor.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Piacentini, Emma; Drioli, Enrico; Giorno, Lidietta</p> <p>2011-04-01</p> <p>In this work, a novel strategy for the controlled fabrication of biomolecular stimulus responsive water-in-oil-in-water (W/O/W) multiple emulsion using the membrane emulsification process was investigated. The emulsions interface was functionalized with a biomolecule able to function as a receptor for a target compound. The interaction between the biomolecular receptor and target stimulus activated the release of bioactive molecules contained within the structured emulsion. A glucose sensitive emulsion was investigated as a model study case. Concanavalin A (<span class="hlt">Con</span> A) was used as the biomolecular glucose sensor. Various physicochemical strategies for stimulus responsive materials formulation are available in literature, but the preparation of biomolecule-responsive emulsions has been explored for the first time in this paper. The development of novel drug delivery systems requires advanced and highly precise techniques to obtain their particular properties and targeting requirements. The present study has proven the flexibility and suitability of membrane emulsification for the preparation of stable and functional multiple emulsions containing <span class="hlt">Con</span> A as interfacial biomolecular receptor able to activate the release of a bioactive molecule as a consequence of interaction with the glucose target molecule. The influence of emulsion interfacial composition and membrane emulsification operating conditions on droplets stability and functional properties have been investigated. The release of the bioactive molecule as a function of glucose stimulus and its concentration has been demonstrated. Copyright © 2010 Wiley Periodicals, Inc.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28899798','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28899798"><span>Is ACPA positivity the main driver for rheumatoid arthritis treatment? Pros and <span class="hlt">cons</span>.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Alivernini, Stefano; Galeazzi, Mauro; Peleg, Hagit; Tolusso, Barbara; Gremese, Elisa; Ferraccioli, Gianfranco; Naparstek, Yaakov</p> <p>2017-11-01</p> <p>Rheumatoid Arthritis (RA) is an autoimmune chronic disease that is characterized by the positivity of various antibodies, the most specific being autoantibodies against citrullinated antigens (ACPA). Despite ACPA are not arthritogenic by themselves, ACPA positive individuals have high risk of RA development and ACPA positivity is associated with severe erosive phenotype and higher mortality rate compared to seronegative RA. Moreover, ACPA status is associated with favorable response to biologics targeting pathways involving autoantibody producing cells as B lymphocytes. In the current review we have discussed the pros and <span class="hlt">cons</span> on the available scientific evidences, regarding the diagnostic, prognostic and management implications of ACPAs in RA. Copyright © 2017 Elsevier B.V. All rights reserved.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25857204','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25857204"><span>What to consider when regulating electronic cigarettes: Pros, <span class="hlt">cons</span> and unintended consequences.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Caponnetto, Pasquale; Saitta, Daniela; Sweanor, David; Polosa, Riccardo</p> <p>2015-06-01</p> <p>Many public health experts, medical research societies, large health organizations and policy makers have expressed concerns about the increased popularity of electronic cigarettes and have pushed for more restrictive measures ranging from complete bans to tight regulations of these products either as medicines or as tobacco products. But these concerns have never been adequately qualified nor quantified. Without judicious assessment and thorough evaluation, regulations may have unintended consequences that can do more damage than good in public health terms. In this article, we will appraise the existing prominent regulatory frameworks for e-cigarettes, namely, general consumer product, medicinal product and tobacco product regulation, to highlight their pros and <span class="hlt">cons</span>. Moreover, we provide concrete examples of the unintended consequences which may arise from inappropriate regulatory action. Copyright © 2015 Elsevier B.V. All rights reserved.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015ISPAr.XL5..461Y','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015ISPAr.XL5..461Y"><span>The pros and <span class="hlt">cons</span> about the digital recording of Intangible Cultural Heritage and some strategies</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Yang, H.</p> <p>2015-08-01</p> <p>Intangible Cultural Heritage (referred to as ICH), whose fundamental nature different from the tangible cultural heritage is "Intangible", and the related physical presence of the heritage is not the core content. Digital means have irreplaceable advantages in recording intangible and dynamic ICH resources, while it also needs flexible and rigorous recording means as a support, thus striving to maximize resources recording and protection. This article will focus on the pros and <span class="hlt">cons</span> about the digital recording of ICH, and preliminarily discuss some strategies used in the process of recording.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29469793','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29469793"><span>Lesiones subcutáneas dolorosas en paciente <span class="hlt">con</span> melanoma metastásico: un caso de paniculitis linfocítica asociado a vemurafenib.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Benavente-Villegas, Felipe; Ferrando-Roca, Francisco; Dolz-Gaitón, Raquel; Royo-Peiró, María</p> <p>2017-10-15</p> <p>Vemurafenib ha probado ser una herramienta útil en el tratamiento de melanoma metastásico <span class="hlt">con</span> mutación BRAF-V600E. Los efectos adversos incluyen artralgias, fatiga y toxicidad cutánea, siendo infrecuente la paniculitis. Presentamos el caso de una paciente de 43 años <span class="hlt">con</span> melanoma metastásico que desarrolla lesiones subcutáneas dolorosas en miembros inferiores y superiores, asociadas a clínica sistémica después de 2 semanas de inicio de tratamiento <span class="hlt">con</span> Vemurafenib + Cobimetinib. La histología demostró paniculitis linfocitaria septal y lobulillar. La paciente tuvo mala tolerancia al tratamiento anti diana a dosis plenas, requiriendo su ajuste, generando una corticodependencia para controlar sintomatología, y que finalmente obligó a la descontinuación de la terapia dirigida contra melanoma.  A la fecha, se han descrito 29 casos en la literatura de paniculitis asociada a vemurafenib, siendo la mayoría paniculitis neutrofílicas <span class="hlt">con</span> adecuado control de sintomatología asociando antiinflamatorios no esteroidales y/o corticoides orales sin requerir en su mayoría modificación de la terapia contra melanoma; sin embargo hay que tener presente que pueden haber casos <span class="hlt">con</span> mala evolución que obligan a la reducción de dosis de vemurafenib y descontinuar el tratamiento, como ha ocurrido en nuestro reporte.Vemurafenib has proven to be a useful tool in the treatment of metastatic melanoma with BRAF-V600E mutation. Adverse effects include arthralgia, fatigue, and skin toxicity; panniculitis is a rare complication. We present the case of a 43-year-old patient with metastatic melanoma who developed painful subcutaneous nodules of the lower and upper limbs and associated systemic clinical symptoms after 2 weeks of treatment with vemurafenib plus cobimetinib. Histology showed a septal and lobular lymphocytic panniculitis.The patient had poor tolerance of the full-dose treatment, requiring its adjustment. Systemic corticosteroids were required to control symptomatology</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29349697','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29349697"><span>To share or not to share? Expected pros and <span class="hlt">cons</span> of data sharing in radiological research.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Sardanelli, Francesco; Alì, Marco; Hunink, Myriam G; Houssami, Nehmat; Sconfienza, Luca M; Di Leo, Giovanni</p> <p>2018-06-01</p> <p>The aims of this paper are to illustrate the trend towards data sharing, i.e. the regulated availability of the original patient-level data obtained during a study, and to discuss the expected advantages (pros) and disadvantages (<span class="hlt">cons</span>) of data sharing in radiological research. Expected pros include the potential for verification of original results with alternative or supplementary analyses (including estimation of reproducibility), advancement of knowledge by providing new results by testing new hypotheses (not explored by the original authors) on pre-existing databases, larger scale analyses based on individual-patient data, enhanced multidisciplinary cooperation, reduced publication of false studies, improved clinical practice, and reduced cost and time for clinical research. Expected <span class="hlt">cons</span> are outlined as the risk that the original authors could not exploit the entire potential of the data they obtained, possible failures in patients' privacy protection, technical barriers such as the lack of standard formats, and possible data misinterpretation. Finally, open issues regarding data ownership, the role of individual patients, advocacy groups and funding institutions in decision making about sharing of data and images are discussed. • Regulated availability of patient-level data of published clinical studies (data-sharing) is expected. • Expected benefits include verification/advancement of knowledge, reduced cost/time of research, clinical improvement. • Potential drawbacks include faults in patients' identity protection and data misinterpretation.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li class="active"><span>17</span></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_17 --> <div id="page_18" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li class="active"><span>18</span></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="341"> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28992986','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28992986"><span>Pros and <span class="hlt">cons</span> of vaccination against serogroup B meningococcal disease.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Delgado Rodríguez, Miguel; Domínguez García, Ángela</p> <p>2018-02-09</p> <p>A vaccine has recently been approved in the EU against meningococcal serogroup B, the main cause of meningococcal disease. There is a fierce debate about the decision regarding a universal vaccination in infants older than 2 months, as recommended by the majority of scientific societies. In western Europe the only country to have included the universal vaccination is the United Kingdom, with a lower incidence of the disease than Ireland. Other countries have also adopted it, such as the Czech Republic, Cuba and certain regions of Italy. Numerous cost-effectiveness studies have been published regarding the vaccination with different assumptions, which have supported the decision not to implant the universal vaccination because it exceeds the will to pay for a health benefit. We discuss the pros and <span class="hlt">cons</span> of the universal vaccination against meningococcal B, recommended by the Sociedad Española de Pediatría (Spanish Society of Paediatrics), which as yet has not been implemented. Copyright © 2017 Elsevier España, S.L.U. All rights reserved.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3686769','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3686769"><span>Assessment of Response to Lithium Maintenance Treatment in Bipolar Disorder: A Consortium on Lithium Genetics (<span class="hlt">Con</span>LiGen) Report</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Manchia, Mirko; Adli, Mazda; Akula, Nirmala; Ardau, Raffaella; Aubry, Jean-Michel; Backlund, Lena; Banzato, Claudio EM.; Baune, Bernhard T.; Bellivier, Frank; Bengesser, Susanne; Biernacka, Joanna M.; Brichant-Petitjean, Clara; Bui, Elise; Calkin, Cynthia V.; Cheng, Andrew Tai Ann; Chillotti, Caterina; Cichon, Sven; Clark, Scott; Czerski, Piotr M.; Dantas, Clarissa; Zompo, Maria Del; DePaulo, J. Raymond; Detera-Wadleigh, Sevilla D.; Etain, Bruno; Falkai, Peter; Frisén, Louise; Frye, Mark A.; Fullerton, Jan; Gard, Sébastien; Garnham, Julie; Goes, Fernando S.; Grof, Paul; Gruber, Oliver; Hashimoto, Ryota; Hauser, Joanna; Heilbronner, Urs; Hoban, Rebecca; Hou, Liping; Jamain, Stéphane; Kahn, Jean-Pierre; Kassem, Layla; Kato, Tadafumi; Kelsoe, John R.; Kittel-Schneider, Sarah; Kliwicki, Sebastian; Kuo, Po-Hsiu; Kusumi, Ichiro; Laje, Gonzalo; Lavebratt, Catharina; Leboyer, Marion; Leckband, Susan G.; López Jaramillo, Carlos A.; Maj, Mario; Malafosse, Alain; Martinsson, Lina; Masui, Takuya; Mitchell, Philip B.; Mondimore, Frank; Monteleone, Palmiero; Nallet, Audrey; Neuner, Maria; Novák, Tomás; O’Donovan, Claire; Ösby, Urban; Ozaki, Norio; Perlis, Roy H.; Pfennig, Andrea; Potash, James B.; Reich-Erkelenz, Daniela; Reif, Andreas; Reininghaus, Eva; Richardson, Sara; Rouleau, Guy A.; Rybakowski, Janusz K.; Schalling, Martin; Schofield, Peter R.; Schubert, Oliver K.; Schweizer, Barbara; Seemüller, Florian; Grigoroiu-Serbanescu, Maria; Severino, Giovanni; Seymour, Lisa R.; Slaney, Claire; Smoller, Jordan W.; Squassina, Alessio; Stamm, Thomas; Steele, Jo; Stopkova, Pavla; Tighe, Sarah K.; Tortorella, Alfonso; Turecki, Gustavo; Wray, Naomi R.; Wright, Adam; Zandi, Peter P.; Zilles, David; Bauer, Michael; Rietschel, Marcella; McMahon, Francis J.</p> <p>2013-01-01</p> <p>Objective The assessment of response to lithium maintenance treatment in bipolar disorder (BD) is complicated by variable length of treatment, unpredictable clinical course, and often inconsistent compliance. Prospective and retrospective methods of assessment of lithium response have been proposed in the literature. In this study we report the key phenotypic measures of the “Retrospective Criteria of Long-Term Treatment Response in Research Subjects with Bipolar Disorder” scale currently used in the Consortium on Lithium Genetics (<span class="hlt">Con</span>LiGen) study. Materials and Methods Twenty-nine <span class="hlt">Con</span>LiGen sites took part in a two-stage case-vignette rating procedure to examine inter-rater agreement [Kappa (κ)] and reliability [intra-class correlation coefficient (ICC)] of lithium response. Annotated first-round vignettes and rating guidelines were circulated to expert research clinicians for training purposes between the two stages. Further, we analyzed the distributional properties of the treatment response scores available for 1,308 patients using mixture modeling. Results Substantial and moderate agreement was shown across sites in the first and second sets of vignettes (κ = 0.66 and κ = 0.54, respectively), without significant improvement from training. However, definition of response using the A score as a quantitative trait and selecting cases with B criteria of 4 or less showed an improvement between the two stages (ICC1 = 0.71 and ICC2 = 0.75, respectively). Mixture modeling of score distribution indicated three subpopulations (full responders, partial responders, non responders). Conclusions We identified two definitions of lithium response, one dichotomous and the other continuous, with moderate to substantial inter-rater agreement and reliability. Accurate phenotypic measurement of lithium response is crucial for the ongoing <span class="hlt">Con</span>LiGen pharmacogenomic study. PMID:23840348</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2963432','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2963432"><span>Actitudes Éticas de los estudiantes y egresados en carrera de medicina <span class="hlt">con</span> metodologías activas</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Novaes, Maria Rita Carvalho Garbi; Novaes, Luiz Carlos Garcez; Guilhem, Dirce; Stepke, Fernando Lolas; Silveira, Carla Cristina Costa; Komatsu, Ricardo Shoiti; Trindade, Eliane Mendonça Vilar; Guiotti, Murilo Galvão</p> <p>2010-01-01</p> <p>El presente estudio tiene por objeto desarrollar un diagnostico de la inserción integrada de la ética en la carrera de medicina brasileña <span class="hlt">con</span> una metodología de aprendizaje basada en problemas y describir las percepciones de actitudes éticas de los estudiantes y egresados. El diseño metodológico es un estudio de caso, descriptivo y documental, <span class="hlt">con</span> abordaje cualitativo y cuantitativo. La muestra de esta investigación ha sido constituida por 120 estudiantes y 40 egresados de dos promociones del Curso de Medicina de la ESCS. Este proyecto fue aprobado por el Comité de Ética en Investigación - SES/DF. Los estudiantes y egresados de la ESCS demostraron un buen manejo en el abordaje de los conflictos éticos y respeto a los pacientes. Sin embargo, el análisis de sensibilidad ética mostró una fragilidad en las percepciones y aptitudes inapropiadas de los estudiantes de la carrera de medicina, identificada básicamente en los años iniciales, que necesitan más discusiones sistematizadas sobre los aspectos éticos y bioéticos integrados a las actividades prácticas para estimular y fortalecer la reflexión ética de los estudiantes. PMID:20981242</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4175515','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4175515"><span>Presentación del estudio “Links” de hombres que tienes sexo <span class="hlt">con</span> hombres en Buenos Aires, Argentina</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Carballo-Diéguez, Alex; Ávila, María M; Balán, Iván C.; Marone, Rubén; Pando, María A.; Barreda, Victoria</p> <p>2011-01-01</p> <p>Resumen Estudios previos en Buenos Aires reportaron altas prevalencias de HIV entre HSH, <span class="hlt">con</span> valores que oscilan entre 9 y 14% durante casi 10 años de continuo testeo. El objetivo principal de este estudio fue la evaluación de factores relacionados al comportamiento de alto riesgo para transmisión del HIV entre HSH entre los que se incluyen el conocimiento y factores emocionales, socioculturales y ambientales. Por otro lado se realizó la estimación de prevalencia e incidencia de HIV utilizando RDS (Respondent Driven Sampling), así como la presencia de otras infecciones de transmisión sexual. Por último se evaluaron los hábitos de testeo para HIV indagando que factores facilitan o impiden su realización. El estudio constó de dos fases, en primer lugar una fase cualitativa y posteriormente una fase cuantitativa <span class="hlt">con</span> una duración total de 4 años y medio. Durante la fase cualitativa se realizaron 44 entrevistas individuales en profundidad, 8 grupos focales y 10 observaciones etnográficas (hoteles, baños públicos (“teteras”), cines pornográficos, fiestas privadas, dark rooms y discotecas). Durante la fase cuantitativa del estudio se realizó el reclutamiento de 500 participantes que provinieron de la Ciudad Autónoma de Buenos Aires, así como del Gran Buenos Aires. El reclutamiento se comenzó <span class="hlt">con</span> 16 participantes llamados semillas. Se realizó el diagnóstico de infección por HIV, hepatitis B y C (HBV y HCV), Treponema pallidum, Virus Papiloma Humano (HPV) y Chlamidias. La colaboración establecida entre los grupos de trabajo enfocados en áreas diversas posibilitó el abordaje conjunto de nuevas estrategias de investigación antes no exploradas en nuestro país. Los resultados más relevantes de esta investigación serán progresivamente publicados en sucesivos números de Actualizaciones en SIDA. PMID:25264397</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018JQSRT.205..230A','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018JQSRT.205..230A"><span>Overlap corrections for emissivity calculations of H2O-CO2-<span class="hlt">CO-N</span>2 mixtures</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Alberti, Michael; Weber, Roman; Mancini, Marco</p> <p>2018-01-01</p> <p>Calculations of total gas emissivities of gas mixtures containing several radiatively active species require corrections for band overlapping. In this paper, we generate such overlap correction charts for H2O-CO2-N2, H2O-CO-N2, and CO2-<span class="hlt">CO-N</span>2 mixtures. These charts are applicable in the 0.1-40 bar total pressure range and in the 500 K-2500 K temperature range. For H2O-CO2-N2 mixtures, differences between our charts and Hottel's graphs as well as models of Leckner and Modak are highlighted and analyzed.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/7798609','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/7798609"><span>Lesbian (in)visibility in Italian Renaissance culture: Diana and other cases of donna <span class="hlt">con</span> donna.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Simons, P</p> <p>1994-01-01</p> <p>Current conceptualizations of sexual identity in the West are not necessarily useful to an historian investigating "lesbianism" in the social history and visual representations of different periods. After an overview of Renaissance documents treating donna <span class="hlt">con</span> donna relations which examines the potentially positive effects of condemnation and silence, the paper focuses on Diana, the goddess of chastity, who bathed with her nymphs as an exemplar of female bodies preserved for heterosexual, reproductive pleasures. Yet the self-sufficiency and bodily contact sometimes represented in images of this secluded all-female gathering might suggest "deviant" responses from their viewers.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/23624038','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/23624038"><span>Synthesis, growth, structural, spectral, thermal, chemical etching, linear and nonlinear optical and mechanical studies of an organic single crystal 4-chloro 4-nitrostilbene (<span class="hlt">CONS</span>): a potential NLO material.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Dinakaran, Paul M; Kalainathan, S</p> <p>2013-07-01</p> <p>4-Chloro 4-nitrostilbene (<span class="hlt">CONS</span>) a new organic nonlinear optical material has been synthesized. Employing slow evaporation method, good optical quality single crystals (dimensions up to 6×2×3 mm(3)) have been grown using ethyl methyl ketone (EMK) as a solvent. The grown crystals have been subjected to various characterizations such as single crystal X-ray diffraction, powder XRD, Fourier Transform Infrared spectroscopy (FTIR), proton NMR, solid UV absorption, SHG studies. Single crystal X-ray diffraction reveals that the crystal system belongs to monoclinic with noncentrosymmetric space group P21. The UV-Vis absorption spectrum has been recorded and found that the cut off wavelength is 380 nm. Functional groups and the structure of the title compound have been confirmed by FTIR and (1)H NMR spectroscopic analyses respectively. Molecular mass of the <span class="hlt">CONS</span> confirmed by the high resolution mass spectral analysis .The thermal behavior of the grown crystal has been studied by TG/DTA analysis and it shows the melting point is at 188.66 °C. Dislocations and growth pattern present in the grown crystal revealed by the etching study. The mechanical strength of the <span class="hlt">CONS</span> crystal has been studied by Vicker's hardness measurement. The SHG efficiency of the grown crystal has been determined by Kurtz and Perry powder test which revealed that the <span class="hlt">CONS</span> crystal (327 mV) has 15 times greater efficiency than that of KDP (21.7 mV). Copyright © 2013 Elsevier B.V. All rights reserved.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28595836','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28595836"><span><span class="hlt">CON</span>4EI: Selection of the reference chemicals for hazard identification and labelling of eye irritating chemicals.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Adriaens, E; Alépée, N; Kandarova, H; Drzewieckac, A; Gruszka, K; Guest, R; Willoughby, J A; Verstraelen, S; Van Rompay, A R</p> <p>2017-10-01</p> <p>Assessment of the acute eye irritation potential is part of the international regulatory requirements for testing of chemicals. In the past, several prospective and retrospective validation studies have taken place in the area of serious eye damage/eye irritation testing. Success in terms of complete replacement of the regulatory in vivo Draize rabbit eye test has not yet been achieved. A very important aspect to ensure development of successful alternative test methods and/or strategies for serious eye damage/eye irritation testing is the selection of appropriate reference chemicals. A set of 80 reference chemicals was selected for the CEFIC-LRI-AIMT6-VITO <span class="hlt">CON</span>4EI (CONsortium for in vitro Eye Irritation testing strategy) project, in collaboration with Cosmetics Europe, from the Draize Reference Database published by Cosmetics Europe based on key criteria that were set in their paper (e.g. balanced by important driver of classification and physical state). The most important goals of the <span class="hlt">CON</span>4EI project were to identify the performance of eight in vitro alternative tests in terms of driver of classification and to identify similarities/differences between the methods in order the build a successful testing strategy that can discriminate between all UN GHS categories. This paper provides background on selection of the test chemicals. Copyright © 2017 Elsevier Ltd. All rights reserved.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/20110014954','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/20110014954"><span>Pros, <span class="hlt">Cons</span>, and Alternatives to Weight Based Cost Estimating</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Joyner, Claude R.; Lauriem, Jonathan R.; Levack, Daniel H.; Zapata, Edgar</p> <p>2011-01-01</p> <p>Many cost estimating tools use weight as a major parameter in projecting the cost. This is often combined with modifying factors such as complexity, technical maturity of design, environment of operation, etc. to increase the fidelity of the estimate. For a set of conceptual designs, all meeting the same requirements, increased weight can be a major driver in increased cost. However, once a design is fixed, increased weight generally decreases cost, while decreased weight generally increases cost - and the relationship is not linear. Alternative approaches to estimating cost without using weight (except perhaps for materials costs) have been attempted to try to produce a tool usable throughout the design process - from concept studies through development. This paper will address the pros and <span class="hlt">cons</span> of using weight based models for cost estimating, using liquid rocket engines as the example. It will then examine approaches that minimize the impct of weight based cost estimating. The Rocket Engine- Cost Model (RECM) is an attribute based model developed internally by Pratt & Whitney Rocketdyne for NASA. RECM will be presented primarily to show a successful method to use design and programmatic parameters instead of weight to estimate both design and development costs and production costs. An operations model developed by KSC, the Launch and Landing Effects Ground Operations model (LLEGO), will also be discussed.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28541898','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28541898"><span><span class="hlt">Con</span>-Text: Text Detection for Fine-grained Object Classification.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Karaoglu, Sezer; Tao, Ran; van Gemert, Jan C; Gevers, Theo</p> <p>2017-05-24</p> <p>This work focuses on fine-grained object classification using recognized scene text in natural images. While the state-of-the-art relies on visual cues only, this paper is the first work which proposes to combine textual and visual cues. Another novelty is the textual cue extraction. Unlike the state-of-the-art text detection methods, we focus more on the background instead of text regions. Once text regions are detected, they are further processed by two methods to perform text recognition i.e. ABBYY commercial OCR engine and a state-of-the-art character recognition algorithm. Then, to perform textual cue encoding, bi- and trigrams are formed between the recognized characters by considering the proposed spatial pairwise constraints. Finally, extracted visual and textual cues are combined for fine-grained classification. The proposed method is validated on four publicly available datasets: ICDAR03, ICDAR13, <span class="hlt">Con</span>-Text and Flickr-logo. We improve the state-of-the-art end-to-end character recognition by a large margin of 15% on ICDAR03. We show that textual cues are useful in addition to visual cues for fine-grained classification. We show that textual cues are also useful for logo retrieval. Adding textual cues outperforms visual- and textual-only in fine-grained classification (70.7% to 60.3%) and logo retrieval (57.4% to 54.8%).</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA227701','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA227701"><span>The Foreign Policy of Venezuela Toward El Salvador: 1979-1983</span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>1990-06-01</p> <p>vista extra-regional, la "zona vital" es rica en materiales estrat~gicos, tales como el petr6leo, el <span class="hlt">hierro</span>, y el aluminlo. Adem~s del petr6leo de...nivel de post-grado, en el Area de hidrocarburos para el periodo 1981 / 1982. Ofrecimiento de cooperaci6n en el campo de geologia de uranlo y materiales ...hombre, yo lo conocia, aparte de que era un homnbre muy preparado, muy inteligente , era un fan~tico. *Un fanatico religioso. Yo s6 porque lo digo</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26242312','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26242312"><span>Development of a heptaplex PCR assay for identification of Staphylococcus aureus and <span class="hlt">CoNS</span> with simultaneous detection of virulence and antibiotic resistance genes.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Okolie, Charles Emeka; Wooldridge, Karl G; Turner, David P J; Cockayne, Alan; James, Richard</p> <p>2015-08-05</p> <p>Staphylococcal toxicity and antibiotic resistance (STAAR) have been menacing public health. Although vancomycin-resistant Staphylococcus aureus (VRSA) is currently not as widespread as methicillin-resistant S. aureus (MRSA), genome evolution of MRSA into VRSA, including strains engineered within the same patient under anti-staphylococcal therapy, may build up to future public health concern. To further complicate diagnosis, infection control and anti-microbial chemotherapy, non-sterile sites such as the nares and the skin could contain both S. aureus and coagulase-negative staphylococci (<span class="hlt">CoNS</span>), either of which could harbour mecA the gene driving staphylococcal methicillin-resistance and required for MRSA-VRSA evolution. A new heptaplex PCR assay has been developed which simultaneously detects seven markers for: i) eubacteria (16S rRNA), ii) Staphylococcus genus (tuf), iii) Staphylococcus aureus (spa), iv) <span class="hlt">CoNS</span> (cns), v) Panton-Valentine leukocidin (pvl), vi) methicillin resistance (mecA), and vii) vancomycin resistance (vanA). Following successful validation using 255 reference bacterial strains, applicability to analyse clinical samples was evaluated by direct amplification in spiked blood cultures (n = 89) which returned 100 % specificity, negative and positive predictive values. The new assay has LoD of 1.0x10(3) CFU/mL for the 16S rRNA marker and 1.0x10(4) CFU/mL for six other markers and completes cycling in less than one hour. The speed, sensitivity (100 %), NPV (100 %) and PPV (100 %) suggest the new heptaplex PCR assay could be easily integrated into a routine diagnostic microbiology workflow. Detection of the cns marker allows for unique identification of <span class="hlt">CoNS</span> in mono-microbial and in poly-microbial samples containing mixtures of <span class="hlt">CoNS</span> and S. aureus without recourse to the conventional elimination approach which is ambiguous. In addition to the SA-CoNS differential diagnostic essence of the new assay, inclusion of vanA primers will allow</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/19051848','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/19051848"><span>The new human papillomavirus (HPV) vaccine: pros and <span class="hlt">cons</span> for pediatric and adolescent health.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Thomas, Tami L</p> <p>2008-01-01</p> <p>The new human papillomavirus (HPV) vaccine is a research breakthrough for pediatric/adolescent health to prevent cervical cancer and related morbidity. The annual heath care cost for the treatment of cervical cancer and genital warts is estimated to be more than three billion dollars a year. The new HPV vaccine has incredible potential to improve reproductive health promotion, reduce health care costs, and close health care disparity gaps. However, issues both for and against the new HPV vaccine, including mandating vaccination, high cost of the vaccine, the short duration of protection offered, and the perceived promotion of sexual activity, cause confusion. Pediatric nurses, including those in advanced practice, benefit by understanding the pros and <span class="hlt">cons</span> of these issues in advocating for their patients.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016AGUFM.V11C2787A','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016AGUFM.V11C2787A"><span>Volcanic soil gas 4He/CO2 ratio: a useful geochemical tool for eruption forecasting</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Asensio-Ramos, M.; Perez, N. M.; Padron, E.; Melián, G.; Hernandez Perez, P. A.; Padilla, G.; Barrancos, J.; Rodríguez, F.; Sumino, H.; Calvo, D.</p> <p>2016-12-01</p> <p>Magmatic gases that percolate through volcano's porous flanks in a non-visible (diffuse) way disturb the chemical composition of soil gases at the surface environment of the volcano, generating enrichments of CO2, He and other gases. Two of the gases which have attracted attention in soil degassing studies are He and CO2 because both species have similar low solubility in silicate melts. However, once they are exsolved from the melts, their movement through the crust towards the surface is very different: CO2, which is a reactive gas, is affected by the occurrence of interfering processes, while interaction of He during its ascent is minimum. Their geochemical differences yield higher relative He/CO2 ratios in the fumarole gases than is actually present in the magma, but it decreases when the magma reservoir reaches enough pressure to generate incipient fracture systems approaching the eruption. In this work, we present quasi daily estimations of diffusive He through the whole surface of El <span class="hlt">Hierro</span>, the youngest island of the Canarian archipelago, considering He emission data reported in the literature (Padrón et al., 2013. Geology, 41, 539-542), using the same procedure as for diffuse CO2 emission time series (Melián et al., 2014. J. Geophys. Res., 119, 6976-6991). After the occurrence of more than 11,000 seismic events, a shallow submarine eruption about 2 km off the south coast in the southernmost part of El <span class="hlt">Hierro</span>, started in October 12, 2011 and lasted for 5 month. The herein presented methodology enables the calculation of the diffuse He/CO2 emission ratio of the entire island during the volcanic unrest. Two different emission peaks for both He and CO2, with approximately the same delay between them ( 23 days), were observed. The combination of both time series resulted in a drastic increase in the He/CO2 emission ratio of the island (up to 1.1×10-3) two weeks before the eruption onset. Additionally, a second significant He/CO2 emission peak (up to 5.5×10</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1997BAAA...41...13G','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1997BAAA...41...13G"><span>Probabilidad de colisión de cometas periódicos <span class="hlt">con</span> partículas interplanetarias</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Gil Hutton, R.</p> <p></p> <p>Se presentan resultados sobre la probabilidad de colisión de cometas de corto período <span class="hlt">con</span> la población de partículas interplanetarias presentes en la región del cinturón de asteroides. Se encuentra que este proceso colisional afecta la evolución física de los cometas de manera no despreciable y puede ser el responsable de variaciones de brillo de tipo ``outburst". Se presentan resultados para algunos cometas en particular y se obtiene un límite inferior para el tamaño de los núcleos en función de la distribución de radios del cinturón de asteroides.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015EGUGA..17.1515O','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015EGUGA..17.1515O"><span>Economic and Ethical Consequences of Natural Hazards in Alpine Valleys (EE-<span class="hlt">Con</span>)</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Ortner, Florian; Brantl, Dirk; Meyer, Lukas; Steininger, Karl; Sass, Oliver</p> <p>2015-04-01</p> <p>The Alps and their population are particularly vulnerable to geomorphological and hydrological hazards and this problem might be amplified by ongoing climate change. Natural disasters cause severe monetary damage which often leads to the difficult question whether it socially pays to protect settlements at high costs or whether alternatively settlement areas should better be abandoned. By investigations in the Johnsbachtal and the Kleinsölktal (Styria), the interdisciplinary project "Economic and Ethical Consequences of Natural Hazards in Alpine Valleys" (EE-<span class="hlt">Con</span>), funded by the Austrian Academy of Sciences, seeks to answer the following questions: (1) Are natural hazards and associated damages in fact increasing, and is this due to meteorological triggers, to anthropogenic factors or to internal process dynamics? (2) What is the perception and knowledge of local people, how is risk and risk prevention communicated? (3) What is the respective cost ratio between protection infrastructure, soft measures of adaptation and other options (e.g. reduction of settlement area)? (4) What legitimate claims to compensation do people have, how far does societal responsibility go and where does individual responsibility start if parts of the settlement area had to be abandoned? These questions will be tackled in an interdisciplinary cooperation between geography, economics and normative theory (philosophy). EE-<span class="hlt">Con</span> will follow broadly the path of risk analysis and risk assessment, focusing on the temporal dimension (past - present - future) with the aim to unravel the history of natural hazards in the areas and to analyse the economic values involved. In the following, natural hazard scenarios for the future (2050 and 2100) will be developed considering the economic consequences. Besides this, the project deals with local knowledge, risk perception and risk communication, which will be investigated via group interviews and stakeholder workshops and be integrated into a human</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015SPIE.9451E..0DK','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015SPIE.9451E..0DK"><span>Future of clip-on weapon sights: pros and <span class="hlt">cons</span> from an applications perspective</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Knight, C. Reed; Greenslade, Ken; Francisco, Glen</p> <p>2015-05-01</p> <p>US Domestic, International, allied Foreign National Warfighters and Para-Military First Responders (Police, SWAT, Special Operations, Law Enforcement, Government, Security and more) are put in harm's way all the time. To successfully complete their missions and return home safely are the primary goals of these professionals. Tactical product improvements that affect mission effectiveness and solider survivability are pivotal to understanding the past, present and future of Clip-On in-line weapon sights. Clip-On Weapon Sight (WS) technology was deemed an interim solution by the US Government for use until integrated and fused (day/night multi-sensor) Weapon Sights (WSs) were developed/fielded. Clip-On has now become the solution of choice by Users, Warriors, Soldiers and the US Government. SWaP-C (size, weight and power -cost) has been improved through progressive advances in Clip-On Image Intensified (I2), passive thermal, LL-CMOS and fused technology. Clip-On Weapon Sights are now no longer mounting position sensitive. Now they maintain aim point boresight, so they can be used for longer ranges with increased capabilities while utilizing the existing zeroed weapon and daysight optic. Active illuminated low-light level (both analog I2 and digital LL-CMOS) imaging is rightfully a real-world technology, proven to deliver daytime and low-light level identification confidence. Passive thermal imaging is also a real-world technology, proven to deliver daytime, nighttime and all-weather (including dirty battlefield) target detection confidence. Image processing detection algorithms with intelligent analytics provide documented promise to improve confidence by reducing Users, Warriors and Soldiers' work-loads and improving overall system engagement solution outcomes. In order to understand the future of Clip-On in-line weapon sights, addressing pros and <span class="hlt">cons</span>, this paper starts with an overview of historical weapon sight applications, technologies and stakeholder decisions</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4176920','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4176920"><span>Fuentes de variabilidad en el diagnóstico de gastritis atrófica multifocal asociada <span class="hlt">con</span> la infección por Helicobacter pylori1</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Bravo, Luis Eduardo; Bravo, Juan Carlos; Realpe, José Luis; Zarama, Guillermo; Piazuelo, MarÍa Blanca; Correa, Pelayo</p> <p>2014-01-01</p> <p>RESUMEN Introducción El mapeo de las diferentes regiones del estómago y el número de fragmentos de mucosa gástrica disponibles para evaluación histopatológica son fuentes importantes de variación en el momento de clasificar y hacer la gradación de la gastritis crónica. Objetivos Estimar la sensibilidad del número de fragmentos de mucosa gástrica necesarios para establecer los diagnósticos de gastritis atrófica <span class="hlt">con</span> metaplasia intestinal (MI), displasia y estado de infección por Helicobacter pylori. Además evaluar la variabilidad intra-observador en la clasificación de estas lesiones precursoras del cáncer gástrico. Materiales y métodos En una cohorte de 6 años de seguimiento se evaluaron 1,958 procedimientos de endoscopia realizados por dos gastroenterólogos. En cada procedimiento y de cada participante se obtuvieron 5 biopsias de mucosa gástrica que representaban antro, incisura angularis y cuerpo. Un único patólogo hizo la interpretación histológica de las 5 biopsias y proporcionó un diagnóstico definitivo global que se utilizó como patrón de referencia. Cada fragmento de mucosa gástrica examinado condujo a un diagnóstico individual para cada biopsia que se comparó <span class="hlt">con</span> el patrón de referencia. La variabilidad intra-observador se evaluó en 127 personas que corresponden a una muestra aleatoria de 20% del total de endoscopias hechas a los 72 meses de seguimiento. Resultados La sensibilidad del diagnóstico de MI y displasia gástrica aumentó de manera significativa <span class="hlt">con</span> el número de fragmentos de mucosa gástrica evaluados El sitio anatómico de mayor sensibilidad para el diagnóstico de MI y displasia fue la incisura angularis. Para descubrir H. pylori se logró alta sensibilidad <span class="hlt">con</span> el estudio de un solo fragmento de mucosa gástrica (95.9%) y fue independiente del sitio de obtención de la biopsia. El acuerdo intra-observador para el diagnóstico de gastritis crónica fue 86.1% <span class="hlt">con</span> valor kappa de 0.79 IC 95% (0.76-0.85). Las</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25512846','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25512846"><span>Nest destruction elicits indiscriminate <span class="hlt">con</span>- versus heterospecific brood parasitism in a captive bird.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Shaw, Rachael C; Feeney, William E; Hauber, Mark E</p> <p>2014-12-01</p> <p>Following nest destruction, the laying of physiologically committed eggs (eggs that are ovulated, yolked, and making their way through the oviduct) in the nests of other birds is considered a viable pathway for the evolution of obligate interspecific brood parasitism. While intraspecific brood parasitism in response to nest predation has been experimentally demonstrated, this pathway has yet to be evaluated in an interspecific context. We studied patterns of egg laying following experimental nest destruction in captive zebra finches, Taeniopygia guttata, a frequent intraspecific brood parasite. We found that zebra finches laid physiologically committed eggs indiscriminately between nests containing conspecific eggs and nests containing heterospecific eggs (of Bengalese finches, Lonchura striata vars. domestica), despite the <span class="hlt">con</span>- and heterospecific eggs differing in both size and coloration. This is the first experimental evidence that nest destruction may provide a pathway for the evolution of interspecific brood parasitism in birds.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2012AGUFM.V44B..06P','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2012AGUFM.V44B..06P"><span>Diffuse Helium Emission as a Precursory Sign of Volcanic Unrest</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Padron, E.; Perez, N.; Hernandez Perez, P. A.; Sumino, H.; Melian Rodriguez, G.; Barrancos, J.; Nolasco, D.; Padilla, G.; Dionis, S.; Rodriguez, F.; Hernandez, I.; Calvo, D.; Peraza, M.; Nagao, K.</p> <p>2012-12-01</p> <p>Since July 16, 2011, an anomalous seismicity at El <span class="hlt">Hierro</span> island, the youngest and smallest of the Canary Islands, was recorded by IGN seismic network. After the occurrence of more than 10,000 seismic events, volcanic tremor was recorded since 05:15 of the October 10, by all of the seismic stations on the island, with highest amplitudes recorded in the southernmost station. During the afternoon of October 12 a large light-green coloured area was observed in the sea to the souht of La Restinga village (at the southernmost part of El <span class="hlt">Hierro</span> island), suggesting the existence of a submarine eruption. Since October 12, frequent episodes of, turbulent gas emission and foaming, and the appearance of steamy lava fragments has been observed on the sea surface. As part of the volcanic surveillance of the island, the Instituto Volcanologico de Canarias (INVOLCAN) geochemical monitoring program is carrying out diffuse helium surveys on the surface environment of El <span class="hlt">Hierro</span> (soil atmosphere). This nobel gas has been investigated because it has been considered an almost ideal geochemical indicator because it is chemically inert, physically stable, nonbiogenic, sparingly soluble in water under ambient conditions and almost non-adsorbable. At each survey, 600 sampling sites covering the whole island and following an homogeneous distribution are selected for helium measurements in the soil gases, The helium concentration gradients with respect to its value on air (5.24 ppm) allow us to estimate a pure diffusive emission rate of helium throughout the island. The first survey was carried out on the summer of 2003, when the island was on a quiescence period. At this survey, the amount of helium released by the volcanic system of El <span class="hlt">Hierro</span> was estimated in 6 kg/d. Since the beginning of the seismic unrest, 13 helium emission surveys have been carried out. The helium emission rate has shown an excellent agreement with the evolution of the volcanic crisis of the island, reaching 30 kg</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li class="active"><span>18</span></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_18 --> <div id="page_19" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li class="active"><span>19</span></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="361"> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1996BAAA...40...44C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1996BAAA...40...44C"><span>Cámara CCD Directa <span class="hlt">con</span> el Telescopio de 2.15 m del CASLEO: algunos diagnósticos</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Cellone, S. A.</p> <p></p> <p>Se efectuaron algunas pruebas <span class="hlt">con</span> la cámara CCD (+ Reductor Focal) instalada en el foco Cassegrain del Telescopio de 2.15 m del Complejo Astronómico El Leoncito (CASLEO). Las conclusiones más significativas son: Los tiempos de exposición efectivos difieren de los nominales en una fracción apreciable de segundo. En exposiciones de menos de 3 segundos, la iluminación no es pareja en todo el detector. En consecuencia, se recomiendan los pasos a seguir por los astrónomos tanto durante la observación como en la reducción de sus datos.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1998PhDT........95E','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1998PhDT........95E"><span>Inversor Resonante de Tres Elementos L-LC <span class="hlt">con</span> Caracteristica Cortocircuitable para Aplicaciones de Calentamiento por Induccion</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Espi Huerta, Jose Miguel</p> <p></p> <p>Los generadores de calentamiento por induccion son puentes inversores <span class="hlt">con</span> carga resonante, cuya mision es basicamente crear una corriente sinusoidal de gran amplitud sobre la "bobina de caldeo", que forma parte del tanque resonante. En el interior de esta bobina se introduce la pieza que se desea calentar. EI campo magnetico creado induce corrientes superficiales (corrientes de Foucault) sobre la pieza, que producen su calentamiento. Los tanques resonantes (tambien llamados osciladores) utilizados en la actualidad son el resonante serie y el resonante paralelo. Aunque ya desde hace algun tiempo se vienen construyendo generadores de alta potencia basados en estos dos osciladores, el exito nunca ha. sido completo en ninguno de los dos casos. Tal y como se explica en la introduccion de esta memoria, los puentes inversores utilizados deben operar sobre una carga inductiva (corriente retrasada) para evitar el fenomeno de la recuperacion inversa de sus diodos y la consiguiente ruptura de los transistores. De la restriccion topologica anterior se deduce que el generador paralelo debe conmutar a frecuencias inferiores a la resonancia, y el serie a frecuencias superiores. A esta restriccion topologica hay que unir otra que es exclusiva del calentamiento por induccion: La corriente por la bobina de caldeo debe ser sinusoidal. De no ser asi, resultaria imposible disponer toda la potencia de calentamiento sobre la pieza en el espesor requerido por la aplicacion. Como consecuencia, los inversores no pueden operar por debajo de la frecuencia de resonancia del oscilador, pues en ese caso se amplifican los armonicos de orden superior de la tension/corriente de entrada situados sobre la resonancia, <span class="hlt">con</span> la consiguiente distorsion de la corriente de salida. La conjuncion de las dos restricciones anteriores obligan al inversor paralelo a funcionar a la frecuencia de resonancia del oscilador. Esto imposibilita un control por variacion de frecuencia, regulandose la potencia desde la</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4181968','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4181968"><span>Potential pros and <span class="hlt">cons</span> of external healthcare performance evaluation systems: real-life perspectives on Iranian hospital evaluation and accreditation program</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Jaafaripooyan, Ebrahim</p> <p>2014-01-01</p> <p>Background: Performance evaluation is essential to quality improvement in healthcare. The current study has identified the potential pros and <span class="hlt">cons</span> of external healthcare evaluation programs, utilizing them subsequently to look into the merits of a similar case in a developing country. Methods: A mixed method study employing both qualitative and quantitative data collection and analysis techniques was adopted to achieve the study end. Subject Matter Experts (SMEs) and professionals were approached for two-stage process of data collection. Results: Potential advantages included greater attractiveness of high accreditation rank healthcare organizations to their customers/purchasers and boosted morale of their personnel. Downsides, as such, comprised the programs’ over-reliance on value judgment of surveyors, routinization and incurring undue cost on the organizations. In addition, the improved, standardized care processes as well as the judgmental nature of program survey were associated, as pros and <span class="hlt">cons</span>, to the program investigated by the professionals. Conclusion: Besides rendering a tentative assessment of Iranian hospital evaluation program, the study provides those running external performance evaluations with a lens to scrutinize the virtues of their own evaluation systems through identifying the potential advantages and drawbacks of such programs. Moreover, the approach followed could be utilized for performance assessment of similar evaluation programs. PMID:25279381</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25279381','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25279381"><span>Potential pros and <span class="hlt">cons</span> of external healthcare performance evaluation systems: real-life perspectives on Iranian hospital evaluation and accreditation program.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Jaafaripooyan, Ebrahim</p> <p>2014-09-01</p> <p>Performance evaluation is essential to quality improvement in healthcare. The current study has identified the potential pros and <span class="hlt">cons</span> of external healthcare evaluation programs, utilizing them subsequently to look into the merits of a similar case in a developing country. A mixed method study employing both qualitative and quantitative data collection and analysis techniques was adopted to achieve the study end. Subject Matter Experts (SMEs) and professionals were approached for two-stage process of data collection. Potential advantages included greater attractiveness of high accreditation rank healthcare organizations to their customers/purchasers and boosted morale of their personnel. Downsides, as such, comprised the programs' over-reliance on value judgment of surveyors, routinization and incurring undue cost on the organizations. In addition, the improved, standardized care processes as well as the judgmental nature of program survey were associated, as pros and <span class="hlt">cons</span>, to the program investigated by the professionals. Besides rendering a tentative assessment of Iranian hospital evaluation program, the study provides those running external performance evaluations with a lens to scrutinize the virtues of their own evaluation systems through identifying the potential advantages and drawbacks of such programs. Moreover, the approach followed could be utilized for performance assessment of similar evaluation programs.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29598996','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29598996"><span>Reprint of "<span class="hlt">CON</span>4EI: Selection of the reference chemicals for hazard identification and labelling of eye irritating chemicals".</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Adriaens, E; Alépée, N; Kandarova, H; Drzewieckac, A; Gruszka, K; Guest, R; Willoughby, J A; Verstraelen, S; Van Rompay, A R</p> <p>2018-06-01</p> <p>Assessment of the acute eye irritation potential is part of the international regulatory requirements for testing of chemicals. In the past, several prospective and retrospective validation studies have taken place in the area of serious eye damage/eye irritation testing. Success in terms of complete replacement of the regulatory in vivo Draize rabbit eye test has not yet been achieved. A very important aspect to ensure development of successful alternative test methods and/or strategies for serious eye damage/eye irritation testing is the selection of appropriate reference chemicals. A set of 80 reference chemicals was selected for the CEFIC-LRI-AIMT6-VITO <span class="hlt">CON</span>4EI (CONsortium for in vitro Eye Irritation testing strategy) project, in collaboration with Cosmetics Europe, from the Draize Reference Database published by Cosmetics Europe based on key criteria that were set in their paper (e.g. balanced by important driver of classification and physical state). The most important goals of the <span class="hlt">CON</span>4EI project were to identify the performance of eight in vitro alternative tests in terms of driver of classification and to identify similarities/differences between the methods in order the build a successful testing strategy that can discriminate between all UN GHS categories. This paper provides background on selection of the test chemicals. Copyright © 2018. Published by Elsevier Ltd.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24567291','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24567291"><span>The beliefs about pros and <span class="hlt">cons</span> of drinking and intention to change among hazardous and moderate alcohol users: a population-based cross-sectional study.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Ansker, Fredrik G; Helgason, Asgeir R; Ahacic, Kozma</p> <p>2014-08-01</p> <p>Fundamental to supporting hazardous alcohol users are the rationales for reducing alcohol intake highlighted by the users themselves. This study analyses the relative importance of beliefs about pros and <span class="hlt">cons</span> of drinking in relation to having an intention to reduce intake among both hazardous and moderate alcohol users. Intention to change was assessed in a representative sample of Stockholm's population (n = 4278, response rate 56.5%). Alcohol use was assessed using the Alcohol Use Disorders Identification Test measure. A decisional balance inventory was used to examine various beliefs about the pros and <span class="hlt">cons</span> of drinking, which covered affect changes, social gains and losses, and possible adverse effects. Independent correlations were determined by logistic regression using a backward exclusion procedure (P > 0.05). Higher ratings of importance were generally related to intent, whether or not the contrast was with having no intent or already having made a reduction. This was especially true for hazardous users. Only two beliefs were independently correlated with change among hazardous users: 'Drinking could get me addicted' and 'Drinking makes me more relaxed/less tense' (pseudo-R2 < 0.1). Among moderate users, there was no uniform pattern in the relationships. Unexpectedly, hazardous users with an intent to change rated pro arguments as more important than those with no intent to change. Of the investigated pros and <span class="hlt">cons</span>, only a few were independently related to intention to change drinking behaviour. These arguments provide interesting topics in consultations. Little support was found for any rational decision making behind the intention to reduce alcohol intake. © The Author 2014. Published by Oxford University Press on behalf of the European Public Health Association.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/16952872','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/16952872"><span>Pros and <span class="hlt">cons</span> of the liposome platform in cancer drug targeting.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Gabizon, Alberto A; Shmeeda, Hilary; Zalipsky, Samuel</p> <p>2006-01-01</p> <p>Coating of liposomes with polyethylene-glycol (PEG) by incorporation in the liposome bilayer of PEG-derivatized lipids results in inhibition of liposome uptake by the reticulo-endothelial system and significant prolongation of liposome residence time in the blood stream. Parallel developments in drug loading technology have improved the efficiency and stability of drug entrapment in liposomes, particularly with regard to cationic amphiphiles such as anthracyclines. An example of this new generation of liposomes is a formulation of pegylated liposomal doxorubicin known as Doxil or Caelyx, whose clinical pharmacokinetic profile is characterized by slow plasma clearance and small volume of distribution. A hallmark of these long-circulating liposomal drug carriers is their enhanced accumulation in tumors. The mechanism underlying this passive targeting effect is the phenomenon known as enhanced permeability and retention (EPR) which has been described in a broad variety of experimental tumor types. Further to the passive targeting effect, the liposome drug delivery platform offers the possibility of grafting tumor-specific ligands on the liposome membrane for active targeting to tumor cells, and potentially intracellular drug delivery. The pros and <span class="hlt">cons</span> of the liposome platform in cancer targeting are discussed vis-à-vis nontargeted drugs, using as an example a liposome drug delivery system targeted to the folate receptor.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://images.nasa.gov/#/details-GSFC_20171208_Archive_e001798.html','SCIGOVIMAGE-NASA'); return false;" href="https://images.nasa.gov/#/details-GSFC_20171208_Archive_e001798.html"><span>Canary Islands</span></a></p> <p><a target="_blank" href="https://images.nasa.gov/">NASA Image and Video Library</a></p> <p></p> <p>2012-01-03</p> <p>NASA image acquired December 21, 2011 The rugged landscape of the Canary Islands stood out in sharp contrast to the smooth blue waters of the Atlantic Ocean and the flat tan land of northwestern Africa on December 21, 2011, when the Moderate Resolution Imaging Spectroradiometer (MODIS) aboard the Terra satellite captured this true-color image. The Canary Islands are a group of seven large islands and several smaller islets, all volcanic in origin. The eastern edge of the chain lies only 100 kilometers from the coasts of Morocco and Western Sahara, and the chain stretches for about 500 kilometers across the Atlantic. All the islands are mountainous, and Tenerife, the central island in this image is home to Pico de Teinde, the highest peak, which rises 12,198 feet (3,718 meters) above sea level. From east to west, the islands are named Lanzarote, Fuerteventura, Gran Canaria, Tenerife, La Gomera, La Palmera and El <span class="hlt">Hierro</span>. A bright swirl of peacock blue marks the ocean south of El <span class="hlt">Hierro</span>, a stain on the sea from an ongoing eruption of a volcano under the waters. Credit: NASA/GSFC/Jeff Schmaltz/MODIS Land Rapid Response Team NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/18968916','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/18968916"><span>Classification of commercial wines from the Canary Islands (Spain) by chemometric techniques using metallic contents.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Frías, Sergio; Conde, José E; Rodríguez-Bencomo, Juan J; García-Montelongo, Francisco; Pérez-Trujillo, Juan P</p> <p>2003-02-06</p> <p>Eleven elements, K, Na, Ca, Mg, Fe, Cu, Zn, Mn, Sr, Li and Rb, were determined in dry and sweet wines bearing the denominations of origin of El <span class="hlt">Hierro</span>, La Palma and Lanzarote islands (Canary Islands, Spain). Analyses were performed by flame atomic absorption spectrophotometry, with the exceptions of lithium and rubidium for which flame atomic emission spectrophotometry was used. Sweet wines from La Palma were elaborated as naturally sweet with over-ripe grapes and significant differences were found in all the analysed elements with the exceptions of sodium, iron and rubidium with regard to dry wines from the same island. Contrarily, sweet wines from Lanzarote elaborated with grapes in a similar ripening state to dry wines did not present significant differences between them with the exception of strontium, the content of which was greater in dry wines. Among the three islands, significant differences in mean content were found with the exceptions of iron and copper. Cluster analysis and principal component analysis show differences in wines according to the island of origin and the ripening state of the grapes. Linear discriminant analysis using rubidium, sodium, manganese and strontium, the four most discriminant elements, gave 100% recognition ability and 95.6% prediction ability. The sensitivity and specificity obtained using soft independent modelling of class analogy (SIMCA) as a modelling multivariate technique were both 100% for El <span class="hlt">Hierro</span> and Lanzarote, and 100 and 95%, respectively, for La Palma. The modelling and discriminant capacities of the different metals were also studied.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/23267005','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/23267005"><span>Phylogeography and seed dispersal in islands: the case of Rumex bucephalophorus subsp. canariensis (Polygonaceae).</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Talavera, María; Navarro-Sampedro, Laura; Ortiz, Pedro L; Arista, Montserrat</p> <p>2013-02-01</p> <p>Rumex bucephalophorus subsp. canariensis is an endemic taxon to Macaronesia with diaspore polymorphism. The origin and colonizing route of this taxon in Macaronesia was studied using molecular data and information on diaspore types. Amplified fragment length polymorphism (AFLP) was used in 260 plants from 22 populations of R. bucephalophorus subsp. canariensis, four from the Madeiran archipelago and 18 from the Canary archipelago. Diaspore production was analysed in 9-50 plants from each population used for AFLP analysis. One hundred and one plants from the Madeiran archipelago and 375 plants from the Canary Islands were studied. For each plant the type of diaspore produced was recorded. Overall populations had low genetic diversity but they showed a geographical pattern of genetic diversity that was higher in the older eastern islands than in the younger western ones. Two types of dispersible diaspores were found: in the eastern Canary islands (Lanzarote, Fuerteventura and Gran Canaria), plants produced exclusively long-dispersible diaspores, whereas in the western Canary islands (Tenerife, La Gomera, El <span class="hlt">Hierro</span>) and the Madeiran archipelago plants produced exclusively short-dispersible diaspores. Genetically, the studied populations fell into four main island groups: Lanzarote-Fuerteventura, Gran Canaria, Tenerife-El <span class="hlt">Hierro</span> and La Gomera-Madeira archipelago. A Moroccan origin of R. bucephalophorus subsp. canariensis is hypothesized with a colonization route from the eastern to the western islands. In addition, at least one gene flow event from La Gomera to the Madeiran archipelago has taken place. During the colonization process the type of dispersible diaspore changed so that dispersability decreased in populations of the westernmost islands.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24831263','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24831263"><span>Surgical animal models of neuropathic pain: Pros and <span class="hlt">Cons</span>.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Challa, Siva Reddy</p> <p>2015-03-01</p> <p>One of the biggest challenges for discovering more efficacious drugs for the control of neuropathic pain has been the diversity of chronic pain states in humans. It is now acceptable that different mechanisms contribute to normal physiologic pain, pain arising from tissue damage and pain arising from injury to the nervous system. To study pain transmission, spot novel pain targets and characterize the potential analgesic profile of new chemical entities, numerous experimental animal pain models have been developed that attempt to simulate the many human pain conditions. Among the neuropathic pain models, surgical models have paramount importance in the induction of pain states. Many surgical animal models exist, like the chronic constriction injury (CCI) to the sciatic nerve, partial sciatic nerve ligation (pSNL), spinal nerve ligation (SNL), spared nerve injury (SNI), brachial plexus avulsion (BPA), sciatic nerve transaction (SNT) and sciatic nerve trisection. Most of these models induce responses similar to those found in causalgia, a syndrome of sustained burning pain often seen in the distal extremity after partial peripheral nerve injury in humans. Researchers most commonly use these surgical models in both rats and mice during drug discovery to screen new chemical entities for efficacy in the area of neuropathic pain. However, there is scant literature that provides a comparative discussion of all these surgical models. Each surgical model has its own benefits and limitations. It is very difficult for a researcher to choose a suitable surgical animal model to suit their experimental set-up. Therefore, particular attention has been given in this review to comparatively provide the pros and <span class="hlt">cons</span> of each model of surgically induced neuropathic pain.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27497811','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27497811"><span>Pros and <span class="hlt">cons</span> of circumcision: an evidence-based overview.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Friedman, B; Khoury, J; Petersiel, N; Yahalomi, T; Paul, M; Neuberger, A</p> <p>2016-09-01</p> <p>Based on three large randomized controlled trials (RCTs) conducted in Africa, it can clearly be stated that circumcision lowers the risk of infection with the human immunodeficiency virus (HIV) and some sexually transmitted infections (STIs) among males in settings of high HIV and STI endemicity. Similar effects on STI risk may exist for females, although this may result from an indirect effect of decreasing risk of infection among male partners. It is unknown whether circumcision prevents HIV acquisition in men who have sex with men (MSM), although there might be a protective effect for men who engage mainly in insertive anal intercourse. When the effects of adult circumcision on sexual function and satisfaction of men are examined, high-quality evidence strongly supports lack of harm. Whether circumcision alters sexual satisfaction of female partners is not known as fewer and smaller studies reported conflicting results. Circumcision rarely causes serious complications if practiced by trained practitioners, in a sterile setting, and with a proper follow-up. These conclusions are limited by the lack of high-quality data from areas outside of Africa. RCTs have not been conducted to assess the effects of circumcising infants or MSM. Circumcision has well-proven benefits for people residing in areas with high prevalence of STIs, including HIV, and is not unethical for those who choose to be circumcised or have their children circumcised on religious, social, or cultural grounds. For many others, a definite pro or <span class="hlt">con</span> recommendation, based on a risk-benefit ratio, cannot be made. Copyright © 2016 European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd. All rights reserved.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26248178','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26248178"><span>Arab-American Hookah Smokers: Initiation, and Pros and <span class="hlt">Cons</span> of Hookah Use.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Kassem, Nada O F; Kassem, Noura O; Jackson, Sheila R; Daffa, Reem M; Liles, Sandy; Hovell, Melbourne F</p> <p>2015-09-01</p> <p>To examine initiation, pros and <span class="hlt">cons</span> of hookah tobacco smoking among Arab Americans. In this descriptive cross-sectional study, we recruited a community-based convenience sample of 458 adult Arab-American hookah smokers, mean age 28.4 years, who completed self-administered questionnaires. Irrespective of sex, most participants initiated hookah tobacco use by young adulthood in private homes or hookah lounges influenced by friends and family. Women initiated hookah use later than men. Ever dual smokers (hookah smokers who ever smoked a cigarette) initiated hookah use later than cigarettes; however, early hookah initiators < 18 years initiated hookah and cigarettes concurrently. Participants enjoyed the flavors of hookah tobacco, and complained about coughing, dizziness, and headaches. Early and late initiation of hookah tobacco use warrant prevention programs targeting the youth and older adults in communities, colleges, and middle and high schools that include health education campaigns, and encouragement of voluntary smokefree home rules. Tobacco control policies aimed to prevent initiation of hookah use should include regulation of hookah tobacco flavors, and should target the physical environments in neighborhoods, especially around schools and colleges, to reduce the proliferation of hookah lounges. Dual hookah tobacco and cigarette use warrant continuous monitoring.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27715478','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27715478"><span>In vitro evolution of chemically-modified nucleic acid aptamers: Pros and <span class="hlt">cons</span>, and comprehensive selection strategies.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Lipi, Farhana; Chen, Suxiang; Chakravarthy, Madhuri; Rakesh, Shilpa; Veedu, Rakesh N</p> <p>2016-12-01</p> <p>Nucleic acid aptamers are single-stranded DNA or RNA oligonucleotide sequences that bind to a specific target molecule with high affinity and specificity through their ability to adopt 3-dimensional structure in solution. Aptamers have huge potential as targeted therapeutics, diagnostics, delivery agents and as biosensors. However, aptamers composed of natural nucleotide monomers are quickly degraded in vivo and show poor pharmacodynamic properties. To overcome this, chemically-modified nucleic acid aptamers are developed by incorporating modified nucleotides after or during the selection process by Systematic Evolution of Ligands by EXponential enrichment (SELEX). This review will discuss the development of chemically-modified aptamers and provide the pros and <span class="hlt">cons</span>, and new insights on in vitro aptamer selection strategies by using chemically-modified nucleic acid libraries.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5207382','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5207382"><span>In vitro evolution of chemically-modified nucleic acid aptamers: Pros and <span class="hlt">cons</span>, and comprehensive selection strategies</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Chen, Suxiang; Chakravarthy, Madhuri; Rakesh, Shilpa; Veedu, Rakesh N.</p> <p>2016-01-01</p> <p>ABSTRACT Nucleic acid aptamers are single-stranded DNA or RNA oligonucleotide sequences that bind to a specific target molecule with high affinity and specificity through their ability to adopt 3-dimensional structure in solution. Aptamers have huge potential as targeted therapeutics, diagnostics, delivery agents and as biosensors. However, aptamers composed of natural nucleotide monomers are quickly degraded in vivo and show poor pharmacodynamic properties. To overcome this, chemically-modified nucleic acid aptamers are developed by incorporating modified nucleotides after or during the selection process by Systematic Evolution of Ligands by EXponential enrichment (SELEX). This review will discuss the development of chemically-modified aptamers and provide the pros and <span class="hlt">cons</span>, and new insights on in vitro aptamer selection strategies by using chemically-modified nucleic acid libraries. PMID:27715478</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://pubs.er.usgs.gov/publication/70016446','USGSPUBS'); return false;" href="https://pubs.er.usgs.gov/publication/70016446"><span>Large landslides from oceanic volcanoes</span></a></p> <p><a target="_blank" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Holcomb, R.T.; Searle, R.C.</p> <p>1991-01-01</p> <p>Large landslides are ubiquitous around the submarine flanks of Hawaiian volcanoes, and GLORIA has also revealed large landslides offshore from Tristan da Cunha and El <span class="hlt">Hierro</span>. On both of the latter islands, steep flanks formerly attributed to tilting or marine erosion have been reinterpreted as landslide headwalls mantled by younger lava flows. These landslides occur in a wide range of settings and probably represent only a small sample from a large population. They may explain the large volumes of archipelagic aprons and the stellate shapes of many oceanic volcanoes. Large landslides and associated tsunamis pose hazards to many islands. -from Authors</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3459031','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3459031"><span>On the occurrence of egg masses of the diamond-shaped squid Thysanoteuthis rhombus Troschel, 1857 in the subtropical eastern Atlantic (Canary Islands). A potential commercial species?</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Pérez, Alejandro Escánez; Elena, Rodrigo Riera; González, Ángel Francisco González; Sierra, Ángel Guerra</p> <p>2012-01-01</p> <p>Abstract Data on opportunistic sightings of diamond-shaped squid Thysanoteuthis rhombus egg masses in the Canary Islands (Atlantic Ocean) are presented. A total of 16 egg masses of this species were recorded and photographed from 2000 to 2010 around the western islands of the archipelago (El <span class="hlt">Hierro</span>, Tenerife and La Gomera). These data reveal the existence of an important spawning area for diamond-shaped squid around the Canary Islands, in subtropical east Atlantic waters. We provide preliminary data for the potential development of an artisanal fishery focused on this species, and a discussion on its potential impacts on the marine ecosystem. PMID:23129987</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/7963444','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/7963444"><span>Pros and <span class="hlt">cons</span> of BCG vaccination in countries with low incidence of tuberculosis.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Tala, E O; Tala-Heikkilä, M M</p> <p>1994-07-01</p> <p>Preventive bacille Calmette-Guérin (BCG) vaccination, together with case finding and effective chemotherapy, has formed an integral part of the tuberculosis (TB) control program in most countries. In some low-incidence countries the balance of prevention has been more on the side of chemoprophylaxis than of BCG vaccination. The time clearly has come when the strategy of mass BCG vaccination no longer is indicated medically, nor is it cost-effective. The pros and <span class="hlt">cons</span> of the programs need to be critically evaluated against the present epidemiological background, taking into account the facts that TB, the killer disease, is recovering strength, human immunodeficiency virus infection is on the increase, and multidrug-resistant TB has changed the outcome of this previously fully curable disease. Although no longer appropriate for mass programs, BCG vaccination still should be considered for the protection of selected risk groups in low-incidence countries. The overall efficacy may be of the order 50% to 80%, but the variation is great. Therefore, further research urgently is needed on the effectiveness of BCG as an intervention in local TB programs.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014PhDT.......418M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014PhDT.......418M"><span>Estudio de la influencia de la refrigeracion <span class="hlt">con</span> aire de forma natural e inducida en el comportamiento de instalaciones fotovoltaicas</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Mazon Hernandez, Rocio</p> <p></p> <p> panels are analysed to compare and select the best configuration. The presented research provides a deep knowledge of how they work as well as information and results for an improvement in future designs of building integrated photovoltaic systems. Este estudio se centra en analizar la influencia negativa de la temperatura en la produccion electrica de paneles fotovoltaicos al estar emplazados sobre cubierta de acero, como sucede en naves industriales y sobre un invernadero. Se estudian diferentes configuraciones que permitan refrigerar los paneles, reduciendo su temperatura y mejorar su rendimiento. Para abordar este problema, se han construido dos instalaciones experimentales, fieles a plantas solares en funcionamiento. Una instalacion engloba dos paneles fotovoltaicos sobre estructura fija al suelo. Uno de los paneles esta integrado sobre una superficie paralela y metalica. Entre ambas superficies existe un espacio que posibilita circular aire, permitiendo refrigerar el panel por conveccion natural, o conveccion forzada impulsando el aire <span class="hlt">con</span> un ventilador. El otro panel, libre por su cara posterior y se ha considerado de referencia. Se ha estudiado el comportamiento del panel integrado sobre cubierta para diferentes secciones de aire y velocidades inducidas, comparandolo <span class="hlt">con</span> el panel de referencia. Se ha desarrollado un modelo experimental que nos permite determinar la temperatura del panel en funcion de las variables que influyen en su refrigeracion. Adicionalmente, se han analizado los datos de una planta solar en funcionamiento, <span class="hlt">con</span> paneles de igual caracteristicas, obteniendo correlaciones entre la temperatura del panel y las variables electricas y comparandolos <span class="hlt">con</span> las obtenidas en la instalacion experimental. La segunda instalacion experimental reproduce parte de una instalacion solar sobre un invernadero, formada por cuatro paneles fotovoltaicos colocados sobre el plastico del invernadero, existiendo un canal divergente entre ambas superficies. Se estudia la</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2013AGUFM.H11G1225F','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2013AGUFM.H11G1225F"><span>The soil-water balance simulations of a grassland in response to CO2, rainfall, and biodiversity manipulations at Bio<span class="hlt">CON</span></span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Flinker, R. H.; Cardenas, M.; Caldwell, T. G.; Rich, R.; Reich, P.</p> <p>2013-12-01</p> <p>The Bio<span class="hlt">CON</span> (Biodiversity, CO2 and N) experiment has been continuously running since 1997. Operated by the University of Minnesota and located within the Cedar Creek Ecosystem Science Reserve in Minnesota, USA, Bio<span class="hlt">CON</span> is a Free-Air CO2 Enrichment (FACE) experiment that investigates plant community response to three key environmental variables: nitrogen, atmospheric CO2 and biodiversity. More recently rainfall exclusion and temperature manipulation were added to the experiment which amounts to 371 plots. The site attempts to replicate predicted average temperature increases and a northern shift of plant species and any associated consequences. FACE experiments have been conducted for a number of years in different countries, but the focus has generally been on how plant communities, soil respiration and microbes respond. Minimal work has been focused on the hydrologic aspects of these experiments which are potentially valuable for investigating global warming effects on local and plot-scale ecohydrology. Thus, the objective of this work is to characterize and model unsaturated flow for different CO2 and rainfall treatments in order to see how they affect soil moisture dynamics and groundwater recharge on grasslands of central Minnesota. Our study focuses on simulating soil moisture dynamics in eighteen of the Bio<span class="hlt">CON</span> plots: six bare plots with regular rainfall regimes (zero plant species, three plots with elevated atmospheric CO2 levels), six regular rainfall regimes (nine plant species, three plots with elevated atmospheric CO2 levels) and six reduced rainfall regimes (nine plant species, three plots with elevated atmospheric CO2 levels). The Simultaneous Heat and Water (SHAW) model, which solves the Richards equation for unsaturated zone water flow coupled to a comprehensive energy balance model, was parameterized with a combination of field and lab estimates of soil properties. Field estimates of saturated hydraulic conductivity using tension infiltrometers ranged</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li class="active"><span>19</span></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_19 --> <div id="page_20" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li class="active"><span>20</span></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="381"> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27796660','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27796660"><span>Responses of urban crows to <span class="hlt">con</span>- and hetero-specific alarm calls in predator and non-predator zoo enclosures.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Bílá, Kateřina; Beránková, Jana; Veselý, Petr; Bugnyar, Thomas; Schwab, Christine</p> <p>2017-01-01</p> <p>Urban animals and birds in particular are able to cope with diverse novel threats in a city environment such as avoiding novel, unfamiliar predators. Predator avoidance often includes alarm signals that can be used also by hetero-specifics, which is mainly the case in mixed-species flocks. It can also occur when species do not form flocks but co-occur together. In this study we tested whether urban crows use alarm calls of conspecifics and hetero-specifics (jackdaws, Corvus monedula) differently in a predator and a non-predator context with partly novel and unfamiliar zoo animal species. Birds were tested at the Tiergarten Schönbrunn in the city of Vienna by playing back <span class="hlt">con</span>- and hetero-specific alarm calls and control stimuli (great tit song and no stimuli) at predator (wolf, polar bear) and non-predator (eland antelope and cranes, peccaries) enclosures. We recorded responses of crows as the percentage of birds flying away after hearing the playback (out of those present before the playback) and as the number of vocalizations given by the present birds. A significantly higher percentage of crows flew away after hearing either <span class="hlt">con</span>- or hetero-specific alarm calls, but it did not significantly differ between the predator and the non-predator context. Crows treated jackdaw calls just as crow calls, indicating that they make proper use of hetero-specific alarm calls. Responding similarly in both contexts may suggest that the crows were uncertain about the threat a particular zoo animal represents and were generally cautious. In the predator context, however, a high percentage of crows also flew away upon hearing the great tit control song which suggests that they may still evaluate those species which occasionally killed crows as more dangerous and respond to any conspicuous sound.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1989SPIE.1093..523K','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1989SPIE.1093..523K"><span>The Pros And <span class="hlt">Cons</span> Of Various Optical Media For The Soldier's Interfacility Radiographic Record (SIRR) In The Combat Casualty Care System</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Kerlin, Barbara D.; Johnson, William P.</p> <p>1989-05-01</p> <p>Ongoing research and evaluation projects sponsored by the Army Medical Research and Development Command are leading towards filmless radiography in the combat casualty care system of the 1990s. With the elimination of film, the question arises as to the most appropriate medium for archiving and transporting x-ray images and related patient data with the wounded between facilities. This paper considers the pros and <span class="hlt">cons</span> of the various candidate media in relation to their specifications, availability, and appropriateness under simulated combat casualty care conditions.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3555536','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3555536"><span>Phylogeography and seed dispersal in islands: the case of Rumex bucephalophorus subsp. canariensis (Polygonaceae)</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Talavera, María; Navarro-Sampedro, Laura; Ortiz, Pedro L.; Arista, Montserrat</p> <p>2013-01-01</p> <p>Background and Aims Rumex bucephalophorus subsp. canariensis is an endemic taxon to Macaronesia with diaspore polymorphism. The origin and colonizing route of this taxon in Macaronesia was studied using molecular data and information on diaspore types. Methods Amplified fragment length polymorphism (AFLP) was used in 260 plants from 22 populations of R. bucephalophorus subsp. canariensis, four from the Madeiran archipelago and 18 from the Canary archipelago. Diaspore production was analysed in 9–50 plants from each population used for AFLP analysis. One hundred and one plants from the Madeiran archipelago and 375 plants from the Canary Islands were studied. For each plant the type of diaspore produced was recorded. Key Results Overall populations had low genetic diversity but they showed a geographical pattern of genetic diversity that was higher in the older eastern islands than in the younger western ones. Two types of dispersible diaspores were found: in the eastern Canary islands (Lanzarote, Fuerteventura and Gran Canaria), plants produced exclusively long-dispersible diaspores, whereas in the western Canary islands (Tenerife, La Gomera, El <span class="hlt">Hierro</span>) and the Madeiran archipelago plants produced exclusively short-dispersible diaspores. Genetically, the studied populations fell into four main island groups: Lanzarote–Fuerteventura, Gran Canaria, Tenerife–El <span class="hlt">Hierro</span> and La Gomera–Madeira archipelago. Conclusions A Moroccan origin of R. bucephalophorus subsp. canariensis is hypothesized with a colonization route from the eastern to the western islands. In addition, at least one gene flow event from La Gomera to the Madeiran archipelago has taken place. During the colonization process the type of dispersible diaspore changed so that dispersability decreased in populations of the westernmost islands. PMID:23267005</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017EGUGA..19.6271M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017EGUGA..19.6271M"><span>Project "Convective Wind Gusts" (<span class="hlt">Con</span>WinG)</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Mohr, Susanna; Richter, Alexandra; Kunz, Michael; Ruck, Bodo</p> <p>2017-04-01</p> <p>Convectively-driven strong winds usually associated with thunderstorms frequently cause substantial damage to buildings and other structures in many parts of the world. Decisive for the high damage potential are the short-term wind speed maxima with duration of a few seconds, termed as gusts. Several studies have shown that convectively-driven gusts can reach even higher wind speeds compared to turbulent gusts associated with synoptic-scale weather systems. Due to the small-scale and non-stationary nature of convective wind gusts, there is a considerable lack of knowledge regarding their characteristics and statistics. Furthermore, their interaction with urban structures and their influence on buildings is not yet fully understood. For these two reasons, convective wind events are not included in the present wind load standards of buildings and structures, which so far have been based solely on the characteristics of synoptically-driven wind gusts in the near-surface boundary layer (e. g., DIN EN 1991-1-4:2010-12; ASCE7). However, convective and turbulent gusts differ considerably, e.g. concerning vertical wind-speed profiles, gust factors (i.e., maximum to mean wind speed), or exceedance probability curves. In an effort to remedy this situation, the overarching objective of the DFG-project "Convective Wind Gusts" (<span class="hlt">Con</span>WinG) is to investigate the characteristics and statistics of convective gusts as well as their interaction with urban structures. Based on a set of 110 climate stations of the German Weather Service (DWD) between 1992 and 2014, we analyzed the temporal and spatial distribution, intensity, and occurrence probability of convective gusts. Similar to thunderstorm activity, the frequency of convective gusts decreases gradually from South to North Germany. A relation between gust intensity/probability to orography or climate conditions cannot be identified. Rather, high wind speeds, e.g., above 30 m/s, can be expected everywhere in Germany with almost</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/23820156','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/23820156"><span>Food for thought: a pilot study of the pros and <span class="hlt">cons</span> of changing eating patterns within cognitive-behavioural therapy for the eating disorders.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Waller, Glenn; Evans, Jane; Pugh, Matthew</p> <p>2013-09-01</p> <p>Evidence-based cognitive-behavioural therapy (CBT) for the eating disorders has an early focus on behavioural changes around food intake. However, patients' anxiety around such change might account for why they often seem unmotivated in treatment. In order to determine the impact of changing intake, this pilot study of patients with bulimic disorders (N = 19) or anorexia nervosa (N = 9) used a mixed quantitative and qualitative design to retrospectively examine their perspectives of the short- and long-term pros and <span class="hlt">cons</span> of such change. As expected, change was seen negatively in the short-term (with particularly high numbers reporting anxiety), but there were few reports of long-term negative outcomes. In contrast, there were both short- and long-term benefits of changing eating. The patients described what was helpful in making changes and what they had learned as a result. In both cases, their descriptions mapped closely onto the content and process of evidence-based CBT for the eating disorders. Although there is a need for more extensive research, these findings suggest that patients (and therapists) might benefit from being aware of the contrast between the short- and the long-term pros and <span class="hlt">cons</span> of changing eating within CBT for the eating disorders. Copyright © 2013 Elsevier Ltd. All rights reserved.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3955388','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3955388"><span>FACTORES SOCIO-ESTRUCTURALES Y EL ESTIGMA HACIA EL VIH/SIDA: EXPERIENCIAS DE PUERTORRIQUEÑOS/AS <span class="hlt">CON</span> VIH/SIDA AL ACCEDER SERVICIOS DE SALUD</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>RIVERA-DIAZ, MARINILDA; VARAS-DIAZ, NELSON; REYES-ESTRADA, MARCOS; SURO, BEATRIZ; CORIANO, DORALIS</p> <p>2013-01-01</p> <p>RESUMEN El estigma relacionado al VIH/SIDA continúa afectando la prestación de servicios de salud y el bienestar físico y mental de las personas <span class="hlt">con</span> VIH/SIDA (PVS). Recientemente la literatura científica ha señalado la importancia de comprender las manifestaciones de estigma más allá de las interacciones individuales. Por tal razón, investigaciones recientes en y fuera de Puerto Rico enfatizan la importancia de entender cómo factores socio-estructurales (FSE) influyen en los procesos de estigmatización social. <span class="hlt">Con</span> el propósito de examinar los FSE que influyen en las manifestaciones de estigma relacionado al VIH/SIDA, realizamos y analizamos nueve grupos focales compuestos por hombres y mujeres en tratamiento para el VIH/SIDA que habían tenido experiencias estigmatizantes. Los participantes identificaron FSE relacionados a las manifestaciones de estigma, tales como el uso de viviendas especializadas, descentralización de los servicios de salud y el desarrollo de protocolos administrativos excluyentes en los servicios de salud. Los resultados demuestran la importancia de considerar los FSE en el desarrollo e implementación de intervenciones dirigidas a la población. PMID:24639599</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016PhDT.......200D','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016PhDT.......200D"><span>Sequías Hidrológicas en la República Argentina y su relación <span class="hlt">con</span> Variables Macroclimáticas</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Díaz, Erica Betiana</p> <p>2016-07-01</p> <p>Una adecuada planificación y gestión requiere un conocimiento de la distribución temporal y espacial de los recursos hídricos. Una amenaza que afecta al desarrollo y aprovechamiento de los recursos hídricos, y para las cuales la ingeniería debe dar soluciones, son las situaciones de extremos hidrológicos como inundaciones o sequías. Siendo estas últimas un fenómeno hidrológico extremo de gran complejidad del cual aún se conoce poco. <span class="hlt">Con</span> el objetivo de identificar y caracterizar temporal y espacialmente las sequías hidrológicas en Argentina, esta tesis abordó en primera instancia, la identificación y caracterización de sequías desde el punto de vista hidrológico, abarcando el mayor período de tiempo y espacio, en función de los datos de caudales disponibles. <span class="hlt">Con</span> el fin de predecir eventos plurianuales de sequías hidrológicas en el mediano y largo plazo se generaron, a través del análisis espectral y armónico de las series históricas de caudales observados, series sintéticas que reproducen las componentes periódicas plurianuales más significativas de las series observadas. Además, para lograr un avance en el conocimiento de los fenómenos climáticos que conducen a las sequías hidrológicas, se identificaron las variables macroclimáticas que tienen una mayor correlación <span class="hlt">con</span> los caudales escurridos en las distintas cuencas. Esta tesis comprende el estudio de 14 cuencas hidrográficas argentinas, pertenecientes a los ríos Colorado, Mendoza, San Juan, Atuel, Ctalamochita, Anizacate, Xanaes, Suquía, Dulce, Juramento, Salado, Paraná, Bermejo y Pilcomayo. Los resultados a los que se abordaron en esta tesis son de relevancia para la gestión de los recursos hídricos ya que usos tales como el abastecimiento humano, el riego y la producción energética, entre otros, pueden ser seriamente afectados por la ocurrencia de manera simultánea de sequías severas en cuencas que aportan a una región y zonas vecinas.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29332060','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29332060"><span>Information technology as a tool for the Italian Institute of Social Security (INPS) in the management of social security and civil disability: Pro and <span class="hlt">cons</span>.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Sammicheli, Michele; Scaglione, Marcella</p> <p>2018-01-01</p> <p>We examine, from a medical-legal perspective, the pro and <span class="hlt">cons</span> of the information technology procedures that the Italian Institute of Social Security (INPS) has implemented to manage the provision of social disability assistance, meaning that separate from the payment of pension contributions, being welfare, anchored to an administrative requirement by way of the compulsory payment of a minimum social security contribution.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/10690072','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/10690072"><span>Shared governance: time to consider the <span class="hlt">cons</span> as well as the pros.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Gavin, M; Ash, D; Wakefield, S; Wroe, C</p> <p>1999-07-01</p> <p>This paper aims to provide a critical appraisal of an approach to the management and organization of nursing work known as shared governance (SG). This approach has its origins in the USA, where, during the past 20 years it has become increasingly influential. The advocates of SG claim that it can, inter alia, improve recruitment and retention rates, boost morale, and help raise clinical skills. Little wonder that SG in now beginning to make significant inroads into the NHS. ORIGIN OF INFORMATION: However, a trawl through the extensive US literature, using printed and online (e.g. BIDS, CINHAL, MEDLINE, etc.) bibliographical sources, suggests that the claimed benefits of SG should be treated with caution. Much of the existing published research appears to be both methodologically flawed and lacking in any critical edge. While many researchers and commentators appear only too willing to highlight what they see as the promise of SG, they shy away from exploring any potential pitfalls. One consequence of this is that many of the putative benefits SG is said to confer, may in fact be more apparent than real. Nurses and nurse managers need to be apprised of and consider seriously, the possible <span class="hlt">cons</span> as well as the potential pros of SG, if any promise it may have is to be realized.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5486118','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5486118"><span>Autophagic Mechanism in Anti-Cancer Immunity: Its Pros and <span class="hlt">Cons</span> for Cancer Therapy</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Li, Ying-Ying; Feun, Lynn G.; Thongkum, Angkana; Tu, Chiao-Hui; Chen, Shu-Mei; Wangpaichitr, Medhi; Wu, Chunjing; Kuo, Macus T.; Savaraj, Niramol</p> <p>2017-01-01</p> <p>Autophagy, a self-eating machinery, has been reported as an adaptive response to maintain metabolic homeostasis when cancer cells encounter stress. It has been appreciated that autophagy acts as a double-edge sword to decide the fate of cancer cells upon stress factors, molecular subtypes, and microenvironmental conditions. Currently, the majority of evidence support that autophagy in cancer cells is a vital mechanism bringing on resistance to current and prospective treatments, yet whether autophagy affects the anticancer immune response remains unclear and controversial. Accumulated studies have demonstrated that triggering autophagy is able to facilitate anticancer immunity due to an increase in immunogenicity, whereas other studies suggested that autophagy is likely to disarm anticancer immunity mediated by cytotoxic T cells and nature killer (NK) cells. Hence, this contradiction needs to be elucidated. In this review, we discuss the role of autophagy in cancer cells per se and in cancer microenvironment as well as its dual regulatory roles in immune surveillance through modulating presentation of tumor antigens, development of immune cells, and expression of immune checkpoints. We further focus on emerging roles of autophagy induced by current treatments and its impact on anticancer immune response, and illustrate the pros and <span class="hlt">cons</span> of utilizing autophagy in cancer immunotherapy based on preclinical references. PMID:28629173</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/8385653','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/8385653"><span>Effect of PGE2 on thymocyte proliferation induced by <span class="hlt">Con</span> A or IL-4 + PMA.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Daculsi, R; Vaillier, D; Bezian, J H; Gualde, N</p> <p>1993-02-01</p> <p>Prostaglandin E2 (PGE2) is known to inhibit peripheral T-lymphocyte and thymocyte proliferation activated by antigens, mitogens or anti-CD3 antibodies. In this study, we have investigated, the effect of PGE2 on thymocyte proliferation induced by the combination of IL-4 plus PMA. PGE2 inhibits the proliferation of thymocytes activated by <span class="hlt">Con</span>A, whatever the culture period; in contrast PGE2 shifts the kinetics of thymocyte proliferation after stimulation by IL-4 plus PMA, but does not sustain the proliferation beyond day 3. This effect depends upon cell density, IL-4 concentration and on the time that PGE2 is added to the culture. By use of the cAMP inducer, forskolin, or a cAMP analog, db-cAMP, we observed the same results, PGE2 increases the proliferation of CD8+ corticoresistant thymocytes (CRT) activated by IL-4 plus PMA, but inhibits that of CD4+ CRT. These results suggest that PGE2 can regulate thymocyte proliferation differently according to the activation pathway and the thymic subpopulations.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29787413','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29787413"><span>Halving the Volume of Ana<span class="hlt">Con</span>Da: Evaluation of a New Small-Volume Anesthetic Reflector in a Test Lung Model.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Bomberg, Hagen; Meiser, Franziska; Daume, Philipp; Bellgardt, Martin; Volk, Thomas; Sessler, Daniel I; Groesdonk, Heinrich V; Meiser, Andreas</p> <p>2018-05-21</p> <p>Volatile anesthetics are increasingly used for sedation in intensive care units. The most common administration system is Ana<span class="hlt">Con</span>Da-100 mL (ACD-100; Sedana Medical, Uppsala, Sweden), which reflects volatile anesthetics in open ventilation circuits. Ana<span class="hlt">Con</span>Da-50 mL (ACD-50) is a new device with half the volumetric dead space. Carbon dioxide (CO2) can be retained with both devices. We therefore compared the CO2 elimination and isoflurane reflection efficiency of both devices. A test lung constantly insufflated with CO2 was ventilated with a tidal volume of 500 mL at 10 breaths/min. End-tidal CO2 (EtCO2) partial pressure was measured using 3 different devices: a heat-and-moisture exchanger (HME, 35 mL), ACD-100, and ACD-50 under 4 different experimental conditions: ambient temperature pressure (ATP), body temperature pressure saturated (BTPS) conditions, BTPS with 0.4 Vol% isoflurane (ISO-0.4), and BTPS with 1.2 Vol% isoflurane. Fifty breaths were recorded at 3 time points (n = 150) for each device and each condition. To determine device dead space, we adjusted the tidal volume to maintain normocapnia (n = 3), for each device. Thereafter, we determined reflection efficiency by measuring isoflurane concentrations at infusion rates varying from 0.5 to 20 mL/h (n = 3), for each device. EtCO2 was consistently greater with ACD-100 than with ACD-50 and HME (ISO-0.4, mean ± standard deviations: ACD-100, 52.4 ± 0.8; ACD-50, 44.4 ± 0.8; HME, 40.1 ± 0.4 mm Hg; differences of means of EtCO2 [respective 95% confidence intervals]: ACD-100 - ACD-50, 8.0 [7.9-8.1] mm Hg, P < .001; ACD-100 - HME, 12.3 [12.2-12.4] mm Hg, P < .001; ACD-50 - HME, 4.3 [4.2-4.3] mm Hg, P < .001). It was greatest under ATP, less under BTPS, and least with ISO-0.4 and BTPS with 1.2 Vol% isoflurane. In addition to the 100 or 50 mL "volumetric dead space" of each Ana<span class="hlt">Con</span>Da, "reflective dead space" was 40 mL with ACD-100 and 25 mL with ACD-50 when using isoflurane. Isoflurane reflection was highest under ATP</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015E%26PSL.431..140K','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015E%26PSL.431..140K"><span>Deep intrusions, lateral magma transport and related uplift at ocean island volcanoes</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Klügel, Andreas; Longpré, Marc-Antoine; García-Cañada, Laura; Stix, John</p> <p>2015-12-01</p> <p>Oceanic intraplate volcanoes grow by accumulation of erupted material as well as by coeval or discrete magmatic intrusions. Dykes and other intrusive bodies within volcanic edifices are comparatively well studied, but intrusive processes deep beneath the volcanoes remain elusive. Although there is geological evidence for deep magmatic intrusions contributing to volcano growth through uplift, this has rarely been demonstrated by real-time monitoring. Here we use geophysical and petrological data from El <span class="hlt">Hierro</span>, Canary Islands, to show that intrusions from the mantle and subhorizontal transport of magma within the oceanic crust result in rapid endogenous island growth. Seismicity and ground deformation associated with a submarine eruption in 2011-2012 reveal deep subhorizontal intrusive sheets (sills), which have caused island-scale uplift of tens of centimetres. The pre-eruptive intrusions migrated 15-20 km laterally within the lower oceanic crust, opening pathways that were subsequently used by the erupted magmas to ascend from the mantle to the surface. During six post-eruptive episodes between 2012 and 2014, further sill intrusions into the lower crust and upper mantle have caused magma to migrate up to 20 km laterally, resulting in magma accumulation exceeding that of the pre-eruptive phase. A comparison of geobarometric data for the 2011-2012 El <span class="hlt">Hierro</span> eruption with data for other Atlantic intraplate volcanoes shows similar bimodal pressure distributions, suggesting that eruptive phases are commonly accompanied by deep intrusions of sills and lateral magma transport. These processes add significant material to the oceanic crust, cause uplift, and are thus fundamentally important for the growth and evolution of volcanic islands. We suggest that the development of such a magma accumulation zone in the lower oceanic crust begins early during volcano evolution, and is a consequence of increasing size and complexity of the mantle reservoir system, and potentially</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24587269','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24587269"><span>Pronounced fixation, strong population differentiation and complex population history in the Canary Islands blue tit subspecies complex.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Hansson, Bengt; Ljungqvist, Marcus; Illera, Juan-Carlos; Kvist, Laura</p> <p>2014-01-01</p> <p>Evolutionary molecular studies of island radiations may lead to insights in the role of vicariance, founder events, population size and drift in the processes of population differentiation. We evaluate the degree of population genetic differentiation and fixation of the Canary Islands blue tit subspecies complex using microsatellite markers and aim to get insights in the population history using coalescence based methods. The Canary Island populations were strongly genetically differentiated and had reduced diversity with pronounced fixation including many private alleles. In population structure models, the relationship between the central island populations (La Gomera, Tenerife and Gran Canaria) and El <span class="hlt">Hierro</span> was difficult to disentangle whereas the two European populations showed consistent clustering, the two eastern islands (Fuerteventura and Lanzarote) and Morocco weak clustering, and La Palma a consistent unique lineage. Coalescence based models suggested that the European mainland forms an outgroup to the Afrocanarian population, a split between the western island group (La Palma and El <span class="hlt">Hierro</span>) and the central island group, and recent splits between the three central islands, and between the two eastern islands and Morocco, respectively. It is clear that strong genetic drift and low level of concurrent gene flow among populations have shaped complex allelic patterns of fixation and skewed frequencies over the archipelago. However, understanding the population history remains challenging; in particular, the pattern of extreme divergence with low genetic diversity and yet unique genetic material in the Canary Island system requires an explanation. A potential scenario is population contractions of a historically large and genetically variable Afrocanarian population, with vicariance and drift following in the wake. The suggestion from sequence-based analyses of a Pleistocene extinction of a substantial part of North Africa and a Pleistocene/Holocene eastward</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3937385','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3937385"><span>Pronounced Fixation, Strong Population Differentiation and Complex Population History in the Canary Islands Blue Tit Subspecies Complex</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Hansson, Bengt; Ljungqvist, Marcus; Illera, Juan-Carlos; Kvist, Laura</p> <p>2014-01-01</p> <p>Evolutionary molecular studies of island radiations may lead to insights in the role of vicariance, founder events, population size and drift in the processes of population differentiation. We evaluate the degree of population genetic differentiation and fixation of the Canary Islands blue tit subspecies complex using microsatellite markers and aim to get insights in the population history using coalescence based methods. The Canary Island populations were strongly genetically differentiated and had reduced diversity with pronounced fixation including many private alleles. In population structure models, the relationship between the central island populations (La Gomera, Tenerife and Gran Canaria) and El <span class="hlt">Hierro</span> was difficult to disentangle whereas the two European populations showed consistent clustering, the two eastern islands (Fuerteventura and Lanzarote) and Morocco weak clustering, and La Palma a consistent unique lineage. Coalescence based models suggested that the European mainland forms an outgroup to the Afrocanarian population, a split between the western island group (La Palma and El <span class="hlt">Hierro</span>) and the central island group, and recent splits between the three central islands, and between the two eastern islands and Morocco, respectively. It is clear that strong genetic drift and low level of concurrent gene flow among populations have shaped complex allelic patterns of fixation and skewed frequencies over the archipelago. However, understanding the population history remains challenging; in particular, the pattern of extreme divergence with low genetic diversity and yet unique genetic material in the Canary Island system requires an explanation. A potential scenario is population contractions of a historically large and genetically variable Afrocanarian population, with vicariance and drift following in the wake. The suggestion from sequence-based analyses of a Pleistocene extinction of a substantial part of North Africa and a Pleistocene/Holocene eastward</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2003cnam.conf...34M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2003cnam.conf...34M"><span>Cálculos ab initio <span class="hlt">con</span> correlación electrónica</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Merchán Bonete, M.</p> <p></p> <p>Estamos entrando en una era donde la ortogonalidad entre las investigaciones de carácter experimental y de naturaleza teórica se irá difuminando progresivamente y la problemática a resolver quedará en escena como el único actor principal de la obra. Como premisa para una cooperación teórico-experimental de igual a igual, la metodología químico-cuántica utilizada debe ser capaz de ofrecer resultados de carácter predictivo. Sin duda, esta madurez en la metodología químico-cuántica ya la hemos alcanzado hace algunos años, tal y como muestra entre otras muchas, la labor que nuestro grupo ha realizado en el transcurso de la última década, dentro del campo de la Espectroscopía Teórica. Los estudios realizados comprenden una amplia gama de sistemas, variando tanto en tamaño como en complejidad, abordando problemáticas espectroscópicas consideradas tradicionalmente como especialmente controvertidas. Nuestra contribución científica más relevante reside en el carácter cuantitativo de las asignaciones espectroscópicas que hemos propuesto en base a resultados ab initio. Recordemos que en los años noventa los resultados ab initio solían presentar para las energías de excitación de sistemas de tamaño molecular moderado, como el benceno, errores de más de 1 eV. En comparación <span class="hlt">con</span> el éxito relativo de los métodos semiempíricos, la frustración de la metodología ab initio quedaba todavía más patente. Los estudios que hemos presentado representan una comprensión profunda de los espectros electrónicos en sistemas orgánicos claves, mostrando el camino a seguir para obtener asignaciones espectroscópicas precisas (entre 0.1-0.2 eV). La naturaleza del método CASPT2 junto al diseño de estrategias computacionales nos ha permitido alcanzar el carácter cuantitativo <span class="hlt">con</span> el que se caracterizan nuestras contribuciones[1,2]. Por todo ello, algunos de los trabajos publicados se consideran clásicos dentro del campo, pues en cierto modo definen el</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24625100','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24625100"><span>Engaging Community With Promotores de Salud to Support Infant Nutrition and Breastfeeding Among Latinas Residing in Los Angeles County: Salud <span class="hlt">con</span> Hyland's.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Rios-Ellis, Britt; Nguyen-Rodriguez, Selena T; Espinoza, Lilia; Galvez, Gino; Garcia-Vega, Melawhy</p> <p>2015-01-01</p> <p>The Salud <span class="hlt">con</span> Hyland's Project: Comienzo Saludable, Familia Sana [Health With Hyland's Project: Healthy Start, Healthy Family],was developed to provide education and support to Latina mothers regarding healthy infant feeding practices and maternal health. The promotora-delivered intervention was comprised of two charlas (educational sessions) and a supplemental, culturally and linguistically relevant infant feeding and care rolling calendar. Results indicate that the intervention increased intention to breastfeed exclusively, as well as to delay infant initiation of solids by 5 to 6 months. Qualitative feedback identified barriers to maternal and child health education as well as highlighted several benefits of the intervention.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5406131','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5406131"><span>Evaluation of the Arthritis Foundation's Camine <span class="hlt">Con</span> Gusto Program for Hispanic Adults With Arthritis</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Callahan, Leigh F.; Rivadeneira, Alfredo; Altpeter, Mary; Vilen, Leigha; Cleveland, Rebecca J.; Sepulveda, Victoria E.; Hackney, Betsy; Reuland, Daniel S.; Rojas, Claudia</p> <p>2017-01-01</p> <p>Introduction Camine <span class="hlt">Con</span> Gusto (CCG) is the Hispanic version of an evidence-based walking program for people with arthritis. This study examined CCG outcomes, feasibility, tolerability, safety, and acceptability and potential tailoring. Method A pre and post 6-week evaluation was conducted in Hispanic people with arthritis. Outcomes included pain, stiffness, fatigue, functional capacity, helplessness, and self-efficacy. A formative evaluation with program participants and key stakeholders explored program tailoring. Results Participants' mean age was 46.9 years, 44.4% had a high school degree or less, 2.5% were born in United States, 60.1% spoke only Spanish, and 74.7% were female. Moderate effect sizes were found: 0.50 for pain, 0.75 for fatigue, 0.49 for stiffness, 0.33 for function, 0.26 for helplessness, and 0.24 for self-efficacy. There were 285 participants recruited with an 82% 6-week retention (feasibility), no adverse events were reported (safety), and 98% reported program satisfaction (acceptability). Recommended adaptations included simpler language, more pictures and content addressing nutrition and chronic conditions, shortened materials, and inclusion of motivational strategies. Conclusion CCG showed improvement in outcomes in Hispanic individuals comparable to those noted in non-Hispanic White and Black individuals with arthritis. PMID:27553228</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014AGUFMED41B..05H','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014AGUFMED41B..05H"><span>Outreach Opportunities for Early Career Scientists at the Phoenix Comi<span class="hlt">Con</span></span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Horodyskyj, L.; Walker, S. I.; Forrester, J. H.</p> <p>2014-12-01</p> <p>The Phoenix Comi<span class="hlt">Con</span> (PCC) is a rapidly growing annual four-day pop culture event, featuring guests, costuming, exhibits, and discussion panels for popular sci-fi, fantasy, horror, and anime franchises. In 2013, PCC began experimenting with science discussion panels. The popularity of the science programming resulted in an expansion of the track for 2014, which Horodyskyj was responsible for coordinating. Thirty hours of programming were scheduled, including 25 discussion panels, NASA's FameLab, and a Mars room. Panelists included industry specialists, established scientists, STEM outreach enthusiasts, and early career scientists. The majority of the panelists were early career scientists recruited from planetary sciences and biology departments at ASU and UA. Panel topics included cosmology, biotechnology, artificial intelligence, space exploration, astrobiology, and the cross-linkages of each with pop culture. Formats consisted of Q&A, presentations, and interactive game shows. Although most panels were aimed at the general audience, some panels were more specialized. PCC 2014 attracted 77,818 attendees. The science programming received rave reviews from the audience, the PCC management, and the panelists themselves. Many panel rooms were filled to capacity and required crowd control to limit attendance. We observed the formation of science "groupies" who sought out the science panels exclusively and requested more information on other science public events in the Phoenix area. We distributed surveys to several select sessions to evaluate audience reasons for attending the science panels and their opinion of the scientists they observed. We will present the results of these surveys. As the PCC continues to grow at an exponential rate, the science programming will continue to expand. We will discuss ideas for continued expansion of the PCC science programming both to serve the public and as a unique public outreach opportunity for early career scientists.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2000BAAA...44...81B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2000BAAA...44...81B"><span>Perfiles de luminosidad en galaxias <span class="hlt">con</span> núcleo tipo Seyfert 1</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Boris, N.; Rodriguez-Ardilla, A. A.; Pastoriza, M. G.</p> <p></p> <p>Presentamos imágenes CCD en los filtros BVI y Hα de una muestra de 10 galaxias Seyfert 1 y Narrow Line Seyfert 1. Recientes observaciones muestran que hay una diferencia significante en el índice espectral óptico entre NLS1s y Sy1 normales, siendo para las primeras del orden de 2. Otra característica importante es que la mayor parte de las NLS1s muestran tasas de FeII/Hβ mayores que las observadas en otras Sy1s. Desde el punto de vista fotométrico, estas galaxias no tienenningún tipo de estudio previo. Presentamos magnitudes totales, perfiles de luminosidad y mapas de color junto <span class="hlt">con</span> un detallado análisis de la formación estelar en estos objetos. Encontramos que la descomposición en bulbo + disco representa adecuadamente los perfiles de luminosidad de las galaxias de la muestra. Sin embargo, en todos los casos es necesario que el disco tenga un agujero en su centro. El radio de este agujero va desde los 3 a los 9 kpc. Si bien no tenemos aún una explicación para este hecho, los agujeros parecen estar asociados a anillos circumnucleares de alto oscurecimiento E(B-V) ~1. Los perfiles presentan también un fuerte gradiente de color, siendo notablemente más azules hacia la región nuclear. Los objetos de la muestra cubren todo el rango de tipos morfológicos, no obstante, no encontramos regiones de formación estelar en las regiones exteriores de las galaxias. La formación estelar está confinada a la región nuclear y se data en alrededor de 5 x 107 años.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li class="active"><span>20</span></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_20 --> <div id="page_21" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li class="active"><span>21</span></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="401"> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24960241','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24960241"><span>Synthesis of colloidal metal nanocrystals in droplet reactors: the pros and <span class="hlt">cons</span> of interfacial adsorption.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Zhang, Lei; Wang, Yi; Tong, Limin; Xia, Younan</p> <p>2014-07-09</p> <p>Droplet reactors have received considerable attention in recent years as an alternative route to the synthesis and potentially high-volume production of colloidal metal nanocrystals. Interfacial adsorption will immediately become an important issue to address when one seeks to translate a nanocrystal synthesis from batch reactors to droplet reactors due to the involvement of higher surface-to-volume ratios for the droplets and the fact that nanocrystals tend to be concentrated at the water-oil interface. Here we report a systematic study to compare the pros and <span class="hlt">cons</span> of interfacial adsorption of metal nanocrystals during their synthesis in droplet reactors. On the one hand, interfacial adsorption can be used to generate nanocrystals with asymmetric shapes or structures, including one-sixth-truncated Ag octahedra and Au-Ag nanocups. On the other hand, interfacial adsorption has to be mitigated to obtain nanocrystals with uniform sizes and controlled shapes. We confirmed that Triton X-100, a nonionic surfactant, could effectively alleviate interfacial adsorption while imposing no impact on the capping agent typically needed for a shape-controlled synthesis. With the introduction of a proper surfactant, droplet reactors offer an attractive platform for the continuous production of colloidal metal nanocrystals.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4626661','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4626661"><span>Circulating microRNA Biomarkers as Liquid Biopsy for Cancer Patients: Pros and <span class="hlt">Cons</span> of Current Assays</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Ono, Shigeshi; Lam, Stella; Nagahara, Makoto; Hoon, Dave S. B.</p> <p>2015-01-01</p> <p>An increasing number of studies have focused on circulating microRNAs (cmiRNA) in cancer patients’ blood for their potential as minimally-invasive biomarkers. Studies have reported the utility of assessing specific miRNAs in blood as diagnostic/prognostic biomarkers; however, the methodologies are not validated or standardized across laboratories. Unfortunately, there is often minimum limited overlap in techniques between results reported even in similar type studies on the same cancer. This hampers interpretation and reliability of cmiRNA as potential cancer biomarkers. Blood collection and processing, cmiRNA extractions, quality and quantity control of assays, defined patient population assessment, reproducibility, and reference standards all affect the cmiRNA assay results. To date, there is no reported definitive method to assess cmiRNAs. Therefore, appropriate and reliable methodologies are highly necessary in order for cmiRNAs to be used in regulated clinical diagnostic laboratories. In this review, we summarize the developments made over the past decade towards cmiRNA detection and discuss the pros and <span class="hlt">cons</span> of the assays. PMID:26512704</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2000HydJ....8..161S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2000HydJ....8..161S"><span>Stratigraphic and geochemical controls on naturally occurring arsenic in groundwater, eastern Wisconsin, USA</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Schreiber, M. E.; Simo, J. A.; Freiberg, P. G.</p> <p></p> <p> pyrite et dans les sulfates dissous et la corrélation entre les concentrations en sulfates, en fer et en arsenic dissous laissent penser que l'oxydation des sulfures est le processus dominant contrôlant la libération de l'arsenic dans les eaux souterraines. Cependant, les oxy-hydroxydes contenant de l'arsenic sont susceptibles d'être une autre source d'arsenic si des conditions réductrices apparaissent ou s'ils sont transportés dans l'aquifère sous forme de colloïdes. L'analyse des données provenant de puits montre que l'intersection entre le SCH et les niveaux statiques des puits domestiques est fortement corrélée à de fortes concentrations en arsenic dans les eaux souterraines. Des données de terrain et de laboratoire conduisent à penser que la contamination en arsenic la plus forte est causée par l'interaction localisée aux forages entre l'air, l'eau et les sulfures. Bien que la contamination en arsenic soit causée par l'oxydation de sulfures présents naturellement, elle est influencée par les fluctuations du niveau piézométrique causées par les pompages du captage municipal ou par les variations climatiques, ce qui peut conduire au déplacement des zones géographiques où se produisent les contaminations. Resumen Se han medido concentraciones de arsénico muy altas (de hasta 12000μg/L) en las aguas subterráneas de un acuífero confinado, en areniscas, localizado en la parte oriental de Wisconsin (EEUU). La fuente principal de arsénico es un horizonte de cementación secundaria (SCH) <span class="hlt">con</span> un alto contenido en sulfuros, y <span class="hlt">con</span> una gran variabilidad en espesor, morfología y concentraciones de As. El arsénico aparece en piritas y marcasitas, además de en oxihidróxidos de <span class="hlt">hierro</span>, pero no como una fase independiente de arsenopiritas. El hecho que la marca isotópica de piritas y sulfatos disueltos sea muy similar, y que exista una gran correlación entre las concentraciones de sulfato disuelto, <span class="hlt">hierro</span> y arsénico sugiere que la oxidación de</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018JPhCS.953a2206Y','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018JPhCS.953a2206Y"><span>The Using Of <span class="hlt">Fenolic</span> Compounds Of Pluchea indica (L.) Less. Leaves Extracts As A Bioinsecticide And Bioherbicide</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Yuliani; Rahayu, Y. S.</p> <p>2018-01-01</p> <p>Pluchea indica (L.) Less. produces secondary metabolites such as lignans, terpenes, phenylpropanoids, benzoids, tannins, flavonoids, and hydroquinone phenols, used to protect plants against various herbivores, and pathogenic microorganisms, and are used as bioherbicides for weed control. The purpose of this study is to describe the effect of phenolic compounds of leaf extract of Pluchea indica (L.) Less. to the mortality of Spodoptera litura (LC 50 and LC 80) and its effect for seed germination inhibitor of Amaranthus spinosus. The research design was Randomized Completely Design (RCD) with one factor i.e concentration.Test of methanol extract bioactivity on instar two S. litura using five levels of concentrations 0%, 6%, 8%, 10% and 12%, whereas in plants Amaranthus spinoususe lower concentrations 0%, 0,125%, 0,50% and 1%. The parameters measured the mortality of S. litura and the seed germination of A. spinosus which included percentage of germination and germination rate. The results show that the biopesticide developed from plants Pluchea indica can result in mortality 81.90% of S. litura at a concentration of 12%, with LC 50 of 4.00 ± 0.60 % and LC 80 of 9.88 ± 0.61% . As for the seed germination of plants, the higher concentration of P. indica leaf extract resulted higher inhibition on seed germination of Amaranthus spinosus</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2809501','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2809501"><span>SUPPORT Tools for evidence-informed health Policymaking (STP) 16: Using research evidence in balancing the pros and <span class="hlt">cons</span> of policies</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p></p> <p>2009-01-01</p> <p>This article is part of a series written for people responsible for making decisions about health policies and programmes and for those who support these decision makers. In this article, we address the use of evidence to inform judgements about the balance between the pros and <span class="hlt">cons</span> of policy and programme options. We suggest five questions that can be considered when making these judgements. These are: 1. What are the options that are being compared? 2. What are the most important potential outcomes of the options being compared? 3. What is the best estimate of the impact of the options being compared for each important outcome? 4. How confident can policymakers and others be in the estimated impacts? 5. Is a formal economic model likely to facilitate decision making? PMID:20018106</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/20809646','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/20809646"><span>Dietary intake of aluminum in a Spanish population (Canary Islands).</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>González-Weller, Dailos; Gutiérrez, Angel José; Rubio, Carmen; Revert, Consuelo; Hardisson, Arturo</p> <p>2010-10-13</p> <p>The aim of this study was to analyze the aluminum content in foods and beverages most commonly consumed by the Canary Island population to determine the dietary intake of this metal throughout the Canary Islands as a whole and in each of the seven islands (Gran Canaria, Lanzarote, Fuerteventura, Tenerife, La Palma, La Gomera, and El <span class="hlt">Hierro</span>). Four hundred and forty samples were analyzed by ICP-OES. Estimated total intake of aluminum for the Canary population was 10.171 mg/day, slightly higher than the provisional tolerable weekly intake (PTWI; 10 mg/day for a person weighing 70 kg). Aluminum intake by age and sex of the Canary Island population was also determined and compared values from other populations, both national and international.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016IJSEd..38.1841C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016IJSEd..38.1841C"><span>Balancing the pros and <span class="hlt">cons</span> of GMOs: socio-scientific argumentation in pre-service teacher education</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Cinici, Ayhan</p> <p>2016-07-01</p> <p>This study investigates the role of the discursive process in the act of scientific knowledge building. Specifically, it links scientific knowledge building to risk perception of Genetically Modified Organisms (GMOs). To this end, this study designed and implemented a three-stage argumentation programme giving pre-service teachers (PSTs) the opportunity to consider, discuss and construct shared decisions about GMOs. The study involved 101 third-year PSTs from two different classes, randomly divided into control and experimental groups. The study utilised both quantitative and qualitative methods. During the quantitative phase, researchers administered a pre- and post-intervention scale to measure both groups' risk perception of GMOs. During the qualitative phase, data were collected from the experimental group alone through individual and group reports and an open-ended questionnaire. T-test results showed a statistically significant difference between the experimental and control groups' risk perception of GMOs. Qualitative analysis also revealed differences, for example, in PSTs' weighing of the pros and <span class="hlt">cons</span> of scientific research demonstrating positive results of GMOs. In addition, PSTs' acceptance of GMOs increased. Consequently, this study suggests that developing familiarity with scientific enterprise may play an effective role in adopting a scientific perspective as well as a more balanced risk perception of GMOs.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29950735','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29950735"><span>[Reconstrucción ósea de defectos craneales secundarios a traumatismo <span class="hlt">con</span> implantes personalizados].</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Cienfuegos, Ricardo; Fernández, Gerardo; Cruz, Aída; Sierra, Eduardo</p> <p>2018-01-01</p> <p>Los defectos craneales secundarios a traumatismos son frecuentes. Por lo común se reparan de forma secundaria por sintomatología como el síndrome del paciente trepanado, por protección cerebral y por el aspecto cosmético. Históricamente se han utilizado diversos materiales para la reconstrucción. Se presentan cinco casos de pacientes reconstruidos <span class="hlt">con</span> implantes personalizados de polieteretercetona (PEEK) o polimetilmetacrilato poroso (PMMA). Las localizaciones afectaron el frontal, el borde orbitario superior y el techo orbitario en cuatro casos, y la porción lateral del frontal, la zona temporoparietal y el borde del occipital en un caso. La reconstrucción en cuatro pacientes fue entre 6 y 12 meses después de la lesión, y en un caso después de 25 años. En dos casos se requirió expansión tisular antes de colocar el implante. Cuatro pacientes evolucionaron favorablemente, <span class="hlt">con</span> mejoría de los síntomas neurológicos, forma y contorno adecuados, así como un proceso de cicatrización adecuada de los colgajos de piel cabelluda. Un paciente presentó infección por Staphylococcus aureus, atribuida a la presencia de un mucocele y una fístula de la vía aérea a la cavidad craneal, lo que hizo necesario retirar el implante. Los implantes personalizados son un recurso útil para defectos óseos craneales. Brindan resultados satisfactorios desde el punto de vista funcional y cosmético. Deben tomarse precauciones respecto al tratamiento de las lesiones que afecten el seno frontal, para evitar la comunicación entre la vía aérea y la cavidad craneal. Cranial defects due to trauma are frequent. They are usually repaired in a secondary fashion due to features such as syndrome of the trephined, for brain protection and for cosmetic purposes. Historically, various materials have been used for reconstruction. Five cases of patients reconstructed with customized polyetheretherketone (PEEK) o polymethyl methacrylate (PMMA) implants are presented. Defects involved</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5583430','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5583430"><span>Exploring the pros and <span class="hlt">cons</span> of mechanistic case diagrams for problem-based learning</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p></p> <p>2017-01-01</p> <p>Purpose Mechanistic case diagram (MCD) was recommended for increasing the depth of understanding of disease, but with few articles on its specific methods. We address the experience of making MCD in the fullest depth to identify the pros and <span class="hlt">cons</span> of using MCDs in such ways. Methods During problem-based learning, we gave guidelines of MCD for its mechanistic exploration from subcellular processes to clinical features, being laid out in as much detail as possible. To understand the students’ attitudes and depth of study using MCDs, we analyzed the results of a questionnaire in an open format about experiencing MCDs and examined the resulting products. Results Through the responses to questionnaire, we found several favorable outcomes, major of which was deeper insight and comprehensive understanding of disease facilitated by the process of making well-organized diagram. The main disadvantages of these guidelines were the feeling of too much workload and difficulty of finding mechanisms. Students gave suggestions to overcome these problems: cautious reading of comprehensive texts, additional guidance from staff about depth and focus of mechanisms, and cooperative group work. From the analysis of maps, we recognized there should be allowance of diversities in the appearance of maps and many hypothetical connections, which could be related to an insufficient understanding of mechanisms in nature. Conclusion The more detailed an MCD task is, the better students can become acquainted with deep knowledges. However, this advantage should be balanced by the results that there are many ensuing difficulties for the work and deliberate help plans should be prepared. PMID:28870018</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2010RELEA..10...23D','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2010RELEA..10...23D"><span>Conversation with Lara about the Earth and Land. (Spanish Title: Conversando <span class="hlt">con</span> Lara sobre la Tierra y la Teirra.) Conversando com Lara sobre a Terra e a Terra</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>da Conceição Barbosa-Lima, Maria</p> <p>2010-12-01</p> <p>The present article is the analysis of a conversation between the author and Lara, a four-yearold- girl, enrolled in nursery school, while she makes a drawing of the Earth. It took place outside school environment and without any other person around to avoid interference during the interview. According to Ferreira & Silva (2004), a researcher can only comprehend a child's drawing, or form, by listening to him/her while he/she is creating it. Lara presented the traditional flat drawing, picturing the sky parallel to the ground, as reported by Nardi & Carvalho (1996). However, when asked to draw the World - term used by Butterworth et al. (2002), in order to avoid unnecessary confusion - she represented it by a circle, with herself on the surface. Her drawings led to the conclusion that such girl does not know yet the World in which she lives is the Earth, and probably because of that, within her age and consequent maturity, she accurately differentiates the concepts of land and Earth. El presente artículo analiza una entrevista libre, mientras una niña de 4 años y 4 meses, matriculada en el pregrado, dibuja la Tierra. Esta entrevista se realizó fuera del ambiente escolar y sin otra persona alrededor que pudiera interferir. De acuerdo <span class="hlt">con</span> Ferreira Silva (2004), para quien investiga es posible conocer realmente lo que un niño o una niña pone en el papel a través de grafismos y/o dibujos si se lo escucha durante el proceso de creación de la escritura <span class="hlt">con</span> imágenes. La niña, en este caso, representa la Tierra <span class="hlt">con</span> el tradicional dibujo plano y el "cielo" paralelo al suelo, conforme analizaron Nardi & Carvalho (1996). Pero, cuando se Le solicita dibujar el "Mundo" - palabra empleada en un trabajo de Butterworth et al. (2002), <span class="hlt">con</span> intención de no provocar "confusiones" innecesarias a sus sujetos de investigación- lo representa de forma circular, poniéndose sobre su superficie. Sus dibujos llevan a concluir que esta niña aún no tiene conocimiento que el mundo</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29696291','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29696291"><span>Ab initio study of the <span class="hlt">CO-N</span>2 complex: a new highly accurate intermolecular potential energy surface and rovibrational spectrum.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Cybulski, Hubert; Henriksen, Christian; Dawes, Richard; Wang, Xiao-Gang; Bora, Neha; Avila, Gustavo; Carrington, Tucker; Fernández, Berta</p> <p>2018-05-09</p> <p>A new, highly accurate ab initio ground-state intermolecular potential-energy surface (IPES) for the <span class="hlt">CO-N</span>2 complex is presented. Thousands of interaction energies calculated with the CCSD(T) method and Dunning's aug-cc-pVQZ basis set extended with midbond functions were fitted to an analytical function. The global minimum of the potential is characterized by an almost T-shaped structure and has an energy of -118.2 cm-1. The symmetry-adapted Lanczos algorithm was used to compute rovibrational energies (up to J = 20) on the new IPES. The RMSE with respect to experiment was found to be on the order of 0.038 cm-1 which confirms the very high accuracy of the potential. This level of agreement is among the best reported in the literature for weakly bound systems and considerably improves on those of previously published potentials.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017EGUGA..19.4643P','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017EGUGA..19.4643P"><span>Leveling data in geochemical mapping: scope of application, pros and <span class="hlt">cons</span> of existing methods</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Pereira, Benoît; Vandeuren, Aubry; Sonnet, Philippe</p> <p>2017-04-01</p> <p>Geochemical mapping successfully met a range of needs from mineral exploration to environmental management. In Europe and around the world numerous geochemical datasets already exist. These datasets may originate from geochemical mapping projects or from the collection of sample analyses requested by environmental protection regulatory bodies. Combining datasets can be highly beneficial for establishing geochemical maps with increased resolution and/or coverage area. However this practice requires assessing the equivalence between datasets and, if needed, applying data leveling to remove possible biases between datasets. In the literature, several procedures for assessing dataset equivalence and leveling data are proposed. Daneshfar & Cameron (1998) proposed a method for the leveling of two adjacent datasets while Pereira et al. (2016) proposed two methods for the leveling of datasets that contain records located within the same geographical area. Each discussed method requires its own set of assumptions (underlying populations of data, spatial distribution of data, etc.). Here we propose to discuss the scope of application, pros, <span class="hlt">cons</span> and practical recommendations for each method. This work is illustrated with several case studies in Wallonia (Southern Belgium) and in Europe involving trace element geochemical datasets. References: Daneshfar, B. & Cameron, E. (1998), Leveling geochemical data between map sheets, Journal of Geochemical Exploration 63(3), 189-201. Pereira, B.; Vandeuren, A.; Govaerts, B. B. & Sonnet, P. (2016), Assessing dataset equivalence and leveling data in geochemical mapping, Journal of Geochemical Exploration 168, 36-48.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.epa.gov/newsreleases/el-administrador-regional-de-la-epa-pete-lopez-se-reune-con-el-gobernador-de-las-islas','PESTICIDES'); return false;" href="https://www.epa.gov/newsreleases/el-administrador-regional-de-la-epa-pete-lopez-se-reune-con-el-gobernador-de-las-islas"><span>El Administrador Regional de la EPA Pete López se reúne <span class="hlt">con</span> el Gobernador de las Islas Vírgenes Estadounidenses, Kenneth Mapp, comprometiéndose a restablecer las comunidades de Puerto Rico y las USVI</span></a></p> <p><a target="_blank" href="http://www.epa.gov/pesticides/search.htm">EPA Pesticide Factsheets</a></p> <p></p> <p></p> <p>Comunicado de prensa de la EPA: El Administrador Regional de la EPA Pete López se reúne <span class="hlt">con</span> el Gobernador de las Islas Vírgenes Estadounidenses, Kenneth Mapp, comprometiéndose a restablecer las comunidades de Puerto Rico y las USVI</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/20619868','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/20619868"><span>Molecular detection of pathogens in water--the pros and <span class="hlt">cons</span> of molecular techniques.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Girones, Rosina; Ferrús, Maria Antonia; Alonso, José Luis; Rodriguez-Manzano, Jesus; Calgua, Byron; Corrêa, Adriana de Abreu; Hundesa, Ayalkibet; Carratala, Anna; Bofill-Mas, Sílvia</p> <p>2010-08-01</p> <p>Pollution of water by sewage and run-off from farms produces a serious public health problem in many countries. Viruses, along with bacteria and protozoa in the intestine or in urine are shed and transported through the sewer system. Even in highly industrialized countries, pathogens, including viruses, are prevalent throughout the environment. Molecular methods are used to monitor viral, bacterial, and protozoan pathogens, and to track pathogen- and source-specific markers in the environment. Molecular techniques, specifically polymerase chain reaction-based methods, provide sensitive, rapid, and quantitative analytical tools with which to study such pathogens, including new or emerging strains. These techniques are used to evaluate the microbiological quality of food and water, and to assess the efficiency of virus removal in drinking and wastewater treatment plants. The range of methods available for the application of molecular techniques has increased, and the costs involved have fallen. These developments have allowed the potential standardization and automation of certain techniques. In some cases they facilitate the identification, genotyping, enumeration, viability assessment, and source-tracking of human and animal contamination. Additionally, recent improvements in detection technologies have allowed the simultaneous detection of multiple targets in a single assay. However, the molecular techniques available today and those under development require further refinement in order to be standardized and applicable to a diversity of matrices. Water disinfection treatments may have an effect on the viability of pathogens and the numbers obtained by molecular techniques may overestimate the quantification of infectious microorganisms. The pros and <span class="hlt">cons</span> of molecular techniques for the detection and quantification of pathogens in water are discussed. (c) 2010 Elsevier Ltd. All rights reserved.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2005SEG....75..781J','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2005SEG....75..781J"><span>Using TEM for sounding conductive and deep groundwater in Mars analog environments: Comparing two field studies</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Jernsletten, J. A.</p> <p>2005-11-01</p> <p>A TEM survey was carried out in Pima County, Arizona, in January 2003. Data was collected using 100 m Tx loops and a ferrite-cored magnetic coil Rx antenna, using a 16 Hz sounding frequency, which is sensitive to slightly salty groundwater. Prominent features in the data are the ~500 m depth of investigation and the ~120 m depth to the water table, confirmed by data from four USGS test wells sur-rounding the field area. Note also the conductive (~20-40 Ωm) clay-rich soil above the water table. During May and June of 2003, a Fast-Turnoff (early time) TEM survey was carried out at the Peña de <span class="hlt">Hierro</span> field area of the MARTE project, near the town of Nerva, Spain. Data was collected using 20 m and 40 m Tx loop antennae and 10 m loop Rx antennae, with a 32 Hz sounding frequency. Data from Line 4 (of 16) from this survey, collected using 40 m Tx loops, show ~200 m depth of investigation and a conduc-tive high at ~90 m depth below Station 20 (second station of 10 along this line). This is the water table, matching the 431 m MSL elevation of the nearby pit lake. Data from Line 15 and Line 14 of the Rio Tinto survey, collected using 20 m Tx loops, achieve ~50 m depth of investigation and show <span class="hlt">con</span>-ductive highs at ~15 m depth below Station 50 (Line 15) and Station 30 (Line 14), interpreted as subsurface water flow under mine tailings matching surface flows seen coming out from under the tailings, and shown on maps. Both of the interpretations from Rio Tinto data (Line 4, and Lines 15 & 14) were confirmed by preliminary results from the MARTE ground truth drilling campaign carried out in September and October 2003. Drill Site 1 was moved ~50 m based on recommendations built on data from Line 15 and Line 14 of the Fast-Turnoff TEM survey.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27586259','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27586259"><span>Linking innovative measurement technologies (<span class="hlt">Con</span>Mon and Dataflow© systems) for high-resolution temporal and spatial dissolved oxygen criteria assessment.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>O'Leary, C A; Perry, E; Bayard, A; Wainger, L; Boynton, W R</p> <p>2015-10-01</p> <p>One consequence of nutrient-induced eutrophication in shallow estuarine waters is the occurrence of hypoxia and anoxia that has serious impacts on biota, habitats, and biogeochemical cycles of important elements. Because of the important role of dissolved oxygen (DO) on these ecosystem features, a variety of DO criteria have been established as indicators of system condition. However, DO dynamics are complex and vary on time scales ranging from diel to decadal and spatial scales from meters to multiple kilometers. Because of these complexities, determining DO criteria attainment or failure remains difficult. We propose a method for linking two common measurement technologies for shallow water DO criteria assessment using a Chesapeake Bay tributary as a test case. Dataflow© is a spatially intensive (30-60-m collection intervals) system used to map surface water conditions at the whole estuary scale, and <span class="hlt">Con</span>Mon is a high-frequency (15-min collection intervals) fixed station approach. The former technology is effective with spatial descriptions but poor regarding temporal resolution, while the latter provides excellent temporal but very limited spatial resolution. Our methodology for combining the strengths of these measurement technologies involved a sequence of steps. First, a statistical model of surface water DO dynamics, based on temporally intense <span class="hlt">Con</span>Mon data, was developed. The results of this model were used to calculate daily DO minimum concentrations. Second, this model was then inserted into Dataflow©-generated spatial maps of DO conditions and used to adjust measured DO concentrations to daily minimum concentrations. This information was used to assess DO criteria compliance at the full tributary scale. Model results indicated that it is vital to consider the short-term time scale DO criteria across both space and time concurrently. Large fluctuations in DO occurred within a 24-h time period, and DO dynamics varied across the length and width of the</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/20140001370','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/20140001370"><span>Air Traffic Management Technology Demonstration-1 Concept of Operations (ATD-1 <span class="hlt">Con</span>Ops), Version 2.0</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Baxley, Brian T.; Johnson, William C.; Swenson, Harry N.; Robinson, John E.; Prevot, Tom; Callantine, Todd J.; Scardina, John; Greene, Michael</p> <p>2013-01-01</p> <p>This document is an update to the operations and procedures envisioned for NASA s Air Traffic Management (ATM) Technology Demonstration #1 (ATD-1). The ATD-1 Concept of Operations (<span class="hlt">Con</span>Ops) integrates three NASA technologies to achieve high throughput, fuel-efficient arrival operations into busy terminal airspace. They are Traffic Management Advisor with Terminal Metering (TMA-TM) for precise time-based schedules to the runway and points within the terminal area, Controller-Managed Spacing (CMS) decision support tools for terminal controllers to better manage aircraft delay using speed control, and Flight deck Interval Management (FIM) avionics and flight crew procedures to conduct airborne spacing operations. The ATD-1 concept provides de-conflicted and efficient operations of multiple arrival streams of aircraft, passing through multiple merge points, from top-of-descent (TOD) to the Final Approach Fix. These arrival streams are Optimized Profile Descents (OPDs) from en route altitude to the runway, using primarily speed control to maintain separation and schedule. The ATD-1 project is currently addressing the challenges of integrating the three technologies, and their implantation into an operational environment. The ATD-1 goals include increasing the throughput of high-density airports, reducing controller workload, increasing efficiency of arrival operations and the frequency of trajectory-based operations, and promoting aircraft ADS-B equipage.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/12925313','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/12925313"><span>Pros and <span class="hlt">cons</span> of condom use among gay and bisexual men as explored via the Internet.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Gullette, Donna L; Turner, Joan G</p> <p>2003-01-01</p> <p>The purpose of this study was to conduct a survey utilizing Internet technology related to gay and bisexual men's condom use behavior as an expression of safer sexual practices. A total of 241 self-identified gay and bisexual men responded to the questionnaire in a 3-month period of time. Confidentiality was assured by utilizing an electronic system whereby the respondents e-mail address was eliminated. The study was conceptually guided by the use of the Transtheoretical Model of Behavioral Change (TMC) and the pros and <span class="hlt">cons</span> of condom of use were explored. Fifty-six percent of the participants reported that one advantage (pro) of using condoms with casual partners was that it would make them safer from disease. About half of the respondents (n = 119, 49%) reported a history of one or more sexually transmitted diseases. There were 14 variables found to be significantly associated with using a condom with primary and casual partners among gay and bisexual men. Essentially, findings from this study corresponded to results obtained by more traditional data collection methods. Therefore, the authors conclude that electronic data collection may well be an alternative means for collecting sensitive data such as those collected in this study.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016AGUFMNG12A..09M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016AGUFMNG12A..09M"><span>Volcanic Seismicity - The Power of the b-value</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Main, I. G.; Roberts, N.; Bell, A. F.</p> <p>2016-12-01</p> <p>The Gutenberg-Richter `b-value' is commonly used in volcanic eruption forecasting to infer material or mechanical properties from earthquake distributions. It is `well known' that the b-value tends to be high or very high for volcanic earthquake populations relative to b = 1 for those of tectonic earthquakes, and that b varies significantly with time during periods of unrest. Subject to suitable calibration the b-value also allows us to quantify and characterise earthquake distributions of both ancient and currently-active populations, as a measure of the frequency-size distribution of source rupture area or length. Using a new iterative sampling method (Roberts et al. 2016), we examine data from the El <span class="hlt">Hierro</span> seismic catalogue during a period of unrest in 2011-2013, and quantify the resulting uncertainties. The results demonstrate commonly-applied methods of assessing uncertainty in b-value significantly underestimate the total uncertainty, particularly when b is high. They also show clear multi-modal behaviour in the evolution of the b-value. Individual modes are relatively stable in time, but the most probable b-value intermittently switches between modes, one of which is similar to that of tectonic seismicity, and some are genuinely higher within the total error. A key benefit of this approach is that it is able to resolve different b-values associated with contemporaneous processes, even in the case where some generate high rates of events for short durations and others low rates for longer durations. These characteristics that are typical for many volcanic processes. Secondly, we use a range field observations from the exhumed extinct magma chamber on the Isle of Rum, NW Scotland, to infer an equivalent a b-value for the `frozen' fracture system that would have been active at the time of volcanism 65Ma ago. Using measurements from millimetre-scale fractures to lineation's on satellite imagery over 100m in length, we estimate b=1.8, significantly greater than</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017AGUFMDI51B0309B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017AGUFMDI51B0309B"><span>Isotopic composition of reduced and oxidized sulfur in the Canary Islands: implications for the mantle S cycle</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Beaudry, P.; Longpre, M. A.; Wing, B. A.; Bui, T. H.; Stix, J.</p> <p>2017-12-01</p> <p>The Earth's mantle contains distinct sulfur reservoirs, which can be probed by sulfur isotope analyses of volcanic rocks and gases. We analyzed the isotopic composition of reduced and oxidized sulfur in a diverse range of volcanically derived materials spanning historical volcanism in the Canary Islands. Our sample set consists of subaerial volcanic tephras from three different islands, mantle and sedimentary xenoliths, as well as lava balloon samples from the 2011-2012 submarine El <span class="hlt">Hierro</span> eruption and associated crystal separates. This large sample set allows us to differentiate between the various processes responsible for sulfur isotope heterogeneity in the Canary archipelago. Our results define an array in triple S isotope space between the compositions of the MORB and seawater sulfate reservoirs. Specifically, the sulfide values are remarkably homogeneous around d34S = -1 ‰ and D33S = -0.01 ‰, while sulfate values peak at d34S = +4 ‰ and D33S = +0.01 ‰. Lava balloons from the El <span class="hlt">Hierro</span> eruption have highly enriched sulfate d34S values up to +19.3 ‰, reflecting direct interaction between seawater sulfate and the erupting magma. Several sulfate data points from the island of Lanzarote also trend towards more positive d34S up to +13.8 ‰, suggesting interaction with seawater sulfate-enriched lithologies or infiltration of seawater within the magmatic system. On the other hand, the modal values and relative abundances of S2- and S6+ in crystal separates suggest that the Canary Island mantle source has a d34S around +3 ‰, similar to the S-isotopic composition of a peridotite xenolith from Lanzarote. We infer that the S2- and S6+ modes reflect isotopic equilibrium between those species in the magmatic source, which requires 80 % of the sulfide to become oxidized after melting, consistent with measured S speciation. This 34S enrichment of the source could be due to the recycling of hydrothermally-altered oceanic crust, which has been previously suggested</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li class="active"><span>21</span></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_21 --> <div id="page_22" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li class="active"><span>22</span></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="421"> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016AGUFM.V14A..06G','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016AGUFM.V14A..06G"><span>Eruptive Dynamics Inferred from Textural Analysis of Ash Time Series: The 2015 Reawakening of Cotopaxi Volcano</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Gaunt, H. E.; Bernard, B.; Hidalgo, S.; Proaño, A.; Wright, H. M. N.; Mothes, P. A.; Criollo, E.</p> <p>2016-12-01</p> <p>The eruptive process that took place in October 2011 in the submarine volcano Tagoro off the Island of El <span class="hlt">Hierro</span> (Canary Island) and the subsequent degasification stage, five months later, have increased the concentration of TdFe(II) (Total dissolved iron(II)) in the waters nearest to the volcanic edifice. In order to detect any variation in concentrations of TdFe(II) due to hydrothermal emissions, three cruises were carried out two years after the eruptive process in October 2013, March 2014, May 2015, March 2016 and November 2016. The results from these cruises confirmed important positive anomalies in TdFe(II), which coincided with negatives anomalies in pHF,is (pH in free scale, at in situ conditions) located in the proximity of the main cone. Maximum values in TdFe(II) both at the surface, associated to chlorophyll a maximum, and at the sea bottom, were also observed, showing the important influence of organic complexation and particle re-suspension processes. Temporal variability studies were carried out over periods ranging from hours to days in the stations located over the main and two secondary cones in the volcanic edifice with positive anomalies in TdFe(II) concentrations and negative anomalies in pHF,is values. Observations showed an important variability in both pHF,is and TdFe(II) concentrations, which indicated the volcanic area was affected by a degasification process that remained in the volcano after the eruptive phase had ceased. Fe(II) oxidation kinetic studies were also undertaken in order to analyze the effects of the seawater properties in the proximities of the volcano on the oxidation rate constants and t1/2 (half-life time) of ferrous iron. The increased TdFe(II) concentrations and the low associated pHF,is values acted as an important fertilization event in the seawater around the Tagoro volcano at the Island of El <span class="hlt">Hierro</span> providing optimal conditions for the regeneration of the area.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/19084424','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/19084424"><span>Profitability of our lung retrieval program from non heart beating donors.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Fernández, Elena; Calatayud, Joaquín; Jarabo, José Ramón; Hernando, Florentino; Rodríguez, Olga; Gómez, Ana María; Soria, Ana; Del Río, Francisco</p> <p>2009-02-01</p> <p>In 2002 the first lung transplant from non heart beating (NHB) donors took place in Madrid. The objective of this study was to analyse our Maastricht type I NHB lung donors retrieval program and to check out its profitability. Based on the NHB lung donors retrieval program carried out at Hospital Clínico San Carlos (Madrid) in association with Hospital Puerta de <span class="hlt">Hierro</span> (Madrid), all lung donors from the beginning of the program from June 2002 to December 2006 have been analysed. When faced with a case of sudden death, advanced life support manoeuvres are initiated before 15 min. If the patient meets a given set of criteria, code 0/9 is activated. Arrival time to the hospital cannot exceed 90 min. Femoral artery and vein are cannulated, extracorporeal circulation is started and lungs are preserved. After the relatives' and judicial authorisation lungs are retrieved. Out of a total of 322 occurrences of code 0/9, 43 lung retrievals and 25 implants were reported. A total of 95% of donors were male, with an average age of 41 years and 91% with blood group A or O. 2004 saw the highest number of retrievals (14). January, May and December showed the highest number of retrievals. Incidence of sudden deaths was higher from 7 to 10 a.m. and from 7 to 10 p.m. Twenty-three implants at Hospital Puerta de <span class="hlt">Hierro</span> and three more at Hospital Marqués de Valdecilla (Santander) were reported. A considerable amount of preserved lungs, valid for transplant, were not retrieved because of a lack of an appropriate recipient at the time. A total of 58.1% of preserved lungs were implanted. The ratio of obtained lungs was 11.4% of actual donors and 7.7% of total occurrences. However, this percentage could have been higher if we take into account the number of valid lungs that were not transplanted because of the lack of recipients.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2000BAAA...44...33C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2000BAAA...44...33C"><span>Obtención de perfiles teóricos de elementos metálicos <span class="hlt">con</span> velocidades macroscópicas</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Cirigliano, D.; Costa, A.; Rovira, M.</p> <p></p> <p>El propósito de este trabajo es poder establecer -a partir de la modelización de perfiles de distintas especies- patrones de comparación observacional que permitan caracterizar los fenómenos físicos que están presentes en las estructuras que se observan. Para ello se resuelven las ecuaciones de equilibrio de ionización para un determinado átomo y una atmósfera de parámetros determinados. A partir de ello se definen las poblaciones para los distintos grados de ionización. Considerando distintas configuraciones e intensidades de flujos de masa se deducen la función fuente, el espesor óptico y se calculan los perfiles de las distintas líneas. Se obtuvieron perfiles teóricos de líneas del CII, CIV y del OIV para flujos entrante, saliente y pasante. La forma del perfil, las intensidades relativas entre los distintos flujos y el corrimiento Doppler da cuenta de una caracterización teórica a partir de la cual se comparará <span class="hlt">con</span> observaciones.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26596682','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26596682"><span><span class="hlt">Con</span>-forming bodies: the interplay of machines and bodies and the implications of agency in medical imaging.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Wood, Lisa A</p> <p>2016-06-01</p> <p>Attending to the material discursive constructions of the patient body within cone beam computed tomography (CBCT) imaging in radiotherapy treatments, in this paper I describe how bodies and machines co-create images. Using an analytical framework inspired by Science and Technology Studies and Feminist Technoscience, I describe the interplay between machines and bodies and the implications of materialities and agency. I argue that patients' bodies play a part in producing scans within acceptable limits of machines as set out through organisational arrangements. In doing so I argue that bodies are fabricated into the order of work prescribed and embedded within and around the CBCT system, becoming, not only the subject of resulting images, but part of that image. The scan is not therefore a representation of a passive subject (a body) but co-produced by the work of practitioners and patients who actively control (and contort) and discipline their body according to protocols and instructions and the CBCT system. In this way I suggest they are '<span class="hlt">con</span>-forming' the CBCT image. A Virtual Abstract of this paper can be found at: https://youtu.be/qysCcBGuNSM. © 2015 Foundation for the Sociology of Health & Illness.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.epa.gov/newsreleases/manana-us-epa-national-econ-corporation-demostraran-practicas-seguras-de-trabajo-con','PESTICIDES'); return false;" href="https://www.epa.gov/newsreleases/manana-us-epa-national-econ-corporation-demostraran-practicas-seguras-de-trabajo-con"><span>MAÑANA: U.S. EPA, National Econ Corporation demostrarán prácticas seguras de trabajo <span class="hlt">con</span> plomo para contratistas, se anunciará compromiso para reducir la exposición al plomo en la región</span></a></p> <p><a target="_blank" href="http://www.epa.gov/pesticides/search.htm">EPA Pesticide Factsheets</a></p> <p></p> <p></p> <p>EPA News Release: MAÑANA: U.S. EPA, National Econ Corporation demostrarán prácticas seguras de trabajo <span class="hlt">con</span> plomo para contratistas, se anunciará compromiso para reducir la exposición al plomo en la región</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28802962','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28802962"><span>A skeletal case of hypertrophic osteoarthropathy from the Canary Islands dating from 1000 BP.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>González-Reimers, Emilio; Trujillo-Mederos, Aioze; Machado-Calvo, Manuel; Castañeyra-Ruiz, María; Ordóñez, Alejandra C; Arnay-de-la-Rosa, Matilde</p> <p>2015-12-01</p> <p>A left tibia, the distal right tibia, and the proximal four fifths of the right ulna and radius, probably belonging to an adult prehispanic man (antiquity of ≈1000 years BP) were found among commingled bone remains in a collective burial cave of the island of El <span class="hlt">Hierro</span>, in the Canary Archipelago. All four bones show an intense periosteal bone formation, encrusting the preserved cortical bone of the diaphyses. Differential diagnosis include melorheostosis, syphilis, and leprosy, although the most likely diagnosis is hypertrophic osteoarthropathy, which is usually associated with lung neoplasm or non-malignant diseases leading to chronic hypoxemia. The marked bone proliferation, possibly due to a chronic condition, suggests that possibly the underlying illness was a non-malignant one. Copyright © 2015 Elsevier Inc. All rights reserved.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2003EAEJA.....3324Y','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2003EAEJA.....3324Y"><span>Deformation sequences of the Day Nui <span class="hlt">Con</span> Voi metamorphic belt, northern Vietnam</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Yeh, M. W.; Lee, T. Y.; Lo, C. H.; Chung, S. L.; Lan, C. Y.; Lee, J. C.; Lin, T. S.; Lin, Y. J.</p> <p>2003-04-01</p> <p>The correlation of structure, microstructure and metamorphic assemblages is of fundamental importance to the understanding of the complex tectonic history and kinematics of the Day Nui <span class="hlt">Con</span> Voi (DNCV) metamorphic belt in Vietnam along the Ailao Shan-Red River (ASRR) shear zone as it provides constraints on the relative timing of the deformation, kinematics and metamorphism. High-grade metamorphic rocks of amphibolite faces showed consistent deformation sequences of three folding events followed by one brittle deformation through all four cross sections from Lao Cai to Viet Tri indicated the DNCV belt experienced similar deformation condition throughout its length. The first deformation event, D1, produced up-right folds (locally preserved) with sub-vertical, NE-SW striking axial planes with dextral sense of shear probably formed during the early phase of the lowermost Triassic Indosinian orogeny. Followed by this compressional event is a gravitational collapsing event, D2, which is the major deformation and metamorphic event characterized by kyanite grade metamorphism and large scale horizontal folds with NW-SE (320) striking sub-horizontal axial pane showing sinsistral sense of shear most likely formed during the Oligocene-Miocene SE extrusion of Indochina peninsula. The 3rd folding event, D3, is a post-metamorphism doming event with NW-SE (310) striking sub-vertical axial plane that folded/tilted the once sub-horizontal D2 axial planes into shallowly (<30 degrees) NE dipping on the NE limb, and SW dipping on the SW limb possibly due to left-lateral movement of the N-S trending Xian Shui He fault system in Mid-Miocene. The outward decreasing of the metamorphic grade from kyanite to garnet then biotite indicated the D3 occurred post metamorphism. Reactivation of the sub-horizontal D2 fold axial planes showed dextral sense of shear possibly due to Late Miocene-Pliocene right-lateral movement of the ASRR shear zone. This right lateral movement continuously deformed</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/19596965','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/19596965"><span>Pros and <span class="hlt">cons</span> of intraperitoneal chemotherapy in the treatment of epithelial ovarian cancer.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Zeimet, Alain G; Reimer, Daniel; Radl, Alice C; Reinthaller, Alexander; Schauer, Christian; Petru, Edgar; Concin, Nicole; Braun, Stephan; Marth, Christian</p> <p>2009-07-01</p> <p>Development of the pros and <span class="hlt">cons</span> of intraperitoneal (IP) chemotherapy in the treatment of epithelial ovarian cancer based on the most prominent data published on the evolution of IP chemotherapy and on experience with this therapeutic strategy in clinical routine. The literature published on IP chemotherapy in ovarian cancer between 1970 and 2008 was identified systematically by computer-based searches in MEDLINE and the Cochrane Library. Furthermore, a preliminary analysis of data recorded during an observational nationwide multicenter study of the Austrian AGO on IP-IV chemotherapy using the GOG-172 treatment regimen was performed. The literature review unequivocally revealed a significantly greater toxicity for IP than for intravenous (IV) cisplatin-based chemotherapy. However, according to a Cochrane meta-analysis, IP-IV administration of chemotherapy is associated with a 21.6% decrease in the risk for death. In agreement with earlier reports, the most frequently mentioned side-effects in the Austria-wide observational study were long-lasting neurotoxicity, abdominal pain, fatigue, gastrointestinal and metabolic toxicities, and catheter-related complications. Most of these toxicities were identified as mirroring the toxicity profile of high-dose IV cisplatin (>or=100 mg/m(2)). In some patients, the classic IP-IV regimen with cisplatin/paclitaxel was changed to an alternative schedule comprising carboplatin AUC 5 (d1) and weekly paclitaxel 60 mg/m(2) (d1, 8, 15) completely administered via the IP route. This treatment was better tolerated and quality of life was significantly less compromised. However, neutropenia and thrombocytopenia were the limiting side-effects of this IP regimen. In cases where optimal cytoreduction with residual disease <or=1 cm was achieved during primary surgery and disease was confined to the peritoneal cavity, IP chemotherapy should be given serious consideration, even at the expense of significantly increased, but manageable toxicity.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24841985','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24841985"><span>(<span class="hlt">Con</span>)text-specific effects of visual dysfunction on reading in posterior cortical atrophy.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Yong, Keir X X; Shakespeare, Timothy J; Cash, Dave; Henley, Susie M D; Warren, Jason D; Crutch, Sebastian J</p> <p>2014-08-01</p> <p>Reading deficits are a common early feature of the degenerative syndrome posterior cortical atrophy (PCA) but are poorly understood even at the single word level. The current study evaluated the reading accuracy and speed of 26 PCA patients, 17 typical Alzheimer's disease (tAD) patients and 14 healthy controls on a corpus of 192 single words in which the following perceptual properties were manipulated systematically: inter-letter spacing, font size, length, font type, case and confusability. PCA reading was significantly less accurate and slower than tAD patients and controls, with performance significantly adversely affected by increased letter spacing, size, length and font (cursive < non-cursive), and characterised by visual errors (69% of all error responses). By contrast, tAD and control accuracy rates were at or near ceiling, letter spacing was the only perceptual factor to influence reading speed in the same direction as controls, and, in contrast to PCA patients, control reading was faster for larger font sizes. The inverse size effect in PCA (less accurate reading of large than small font size print) was associated with lower grey matter volume in the right superior parietal lobule. Reading accuracy was associated with impairments of early visual (especially crowding), visuoperceptual and visuospatial processes. However, these deficits were not causally related to a universal impairment of reading as some patients showed preserved reading for small, unspaced words despite grave visual deficits. Rather, the impact of specific types of visual dysfunction on reading was found to be (<span class="hlt">con</span>)text specific, being particularly evident for large, spaced, lengthy words. These findings improve the characterisation of dyslexia in PCA, shed light on the causative and associative factors, and provide clear direction for the development of reading aids and strategies to maximise and sustain reading ability in the early stages of disease. Copyright © 2014. Published by</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4194349','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4194349"><span>(<span class="hlt">Con</span>)text-specific effects of visual dysfunction on reading in posterior cortical atrophy</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Yong, Keir X.X.; Shakespeare, Timothy J.; Cash, Dave; Henley, Susie M.D.; Warren, Jason D.; Crutch, Sebastian J.</p> <p>2014-01-01</p> <p>Reading deficits are a common early feature of the degenerative syndrome posterior cortical atrophy (PCA) but are poorly understood even at the single word level. The current study evaluated the reading accuracy and speed of 26 PCA patients, 17 typical Alzheimer's disease (tAD) patients and 14 healthy controls on a corpus of 192 single words in which the following perceptual properties were manipulated systematically: inter-letter spacing, font size, length, font type, case and confusability. PCA reading was significantly less accurate and slower than tAD patients and controls, with performance significantly adversely affected by increased letter spacing, size, length and font (cursive < non-cursive), and characterised by visual errors (69% of all error responses). By contrast, tAD and control accuracy rates were at or near ceiling, letter spacing was the only perceptual factor to influence reading speed in the same direction as controls, and, in contrast to PCA patients, control reading was faster for larger font sizes. The inverse size effect in PCA (less accurate reading of large than small font size print) was associated with lower grey matter volume in the right superior parietal lobule. Reading accuracy was associated with impairments of early visual (especially crowding), visuoperceptual and visuospatial processes. However, these deficits were not causally related to a universal impairment of reading as some patients showed preserved reading for small, unspaced words despite grave visual deficits. Rather, the impact of specific types of visual dysfunction on reading was found to be (<span class="hlt">con</span>)text specific, being particularly evident for large, spaced, lengthy words. These findings improve the characterisation of dyslexia in PCA, shed light on the causative and associative factors, and provide clear direction for the development of reading aids and strategies to maximise and sustain reading ability in the early stages of disease. PMID:24841985</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/2546349','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/2546349"><span>Experience in managing a large-scale rescreening of Papanicolaou smears and the pros and <span class="hlt">cons</span> of measuring proficiency with visual and written examinations.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Rube, I F</p> <p>1989-01-01</p> <p>Experiences in a large-scale interlaboratory rescreening of Papanicolaou smears are detailed, and the pros and <span class="hlt">cons</span> of measuring proficiency in cytology are discussed. Despite the additional work of the rescreening project and some psychological and technical problems, it proved to be a useful measure of the laboratory's performance as a whole. One problem to be avoided in future similar studies is the creation of too many diagnostic categories. Individual testing and certification have been shown to be accurate predictors of proficiency. For cytology, such tests require a strong visual component to test interpretation and judgment skills, such as by the use of glass slides or photomicrographs. The potential of interactive videodisc technology for facilitating cytopathologic teaching and assessment is discussed.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25616193','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25616193"><span>Monitoring chemical reactions by low-field benchtop NMR at 45 MHz: pros and <span class="hlt">cons</span>.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Silva Elipe, Maria Victoria; Milburn, Robert R</p> <p>2016-06-01</p> <p>Monitoring chemical reactions is the key to controlling chemical processes where NMR can provide support. High-field NMR gives detailed structural information on chemical compounds and reactions; however, it is expensive and complex to operate. Conversely, low-field NMR instruments are simple and relatively inexpensive alternatives. While low-field NMR does not provide the detailed information as the high-field instruments as a result of their smaller chemical shift dispersion and the complex secondary coupling, it remains of practical value as a process analytical technology (PAT) tool and is complimentary to other established methods, such as ReactIR and Raman spectroscopy. We have tested a picoSpin-45 (currently under ThermoFisher Scientific) benchtop NMR instrument to monitor three types of reactions by 1D (1) H NMR: a Fischer esterification, a Suzuki cross-coupling, and the formation of an oxime. The Fischer esterification is a relatively simple reaction run at high concentration and served as proof of concept. The Suzuki coupling is an example of a more complex, commonly used reaction involving overlapping signals. Finally, the oxime formation involved a reaction in two phases that cannot be monitored by other PAT tools. Here, we discuss the pros and <span class="hlt">cons</span> of monitoring these reactions at a low-field of 45 MHz by 1D (1) H NMR. Copyright © 2015 John Wiley & Sons, Ltd. Copyright © 2015 John Wiley & Sons, Ltd.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA135573','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA135573"><span>Application of the New Propulsion Theory to the Design of Propellers. Comparison with the Lifting Line Theory (Aplicacion de la Nueva Teoria de la Impulsion al Diseno de Propulsores. Comparacion <span class="hlt">con</span> la Teoria de las Lineas Sustentadoras),</span></a></p> <p><a target="_blank" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>1983-11-07</p> <p>obtained with the lifting line theory is very sensitive to the type of radial distribution law of circulation. In the past, especially for theoretical...I. Bacquerizo Briones, "Utilidad de la educacion de Poincare para el proyecto y analisis de propulsores <span class="hlt">con</span> valores finitos de la circulacion en el</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28941583','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28941583"><span><span class="hlt">CON</span>4EI: Evaluation of QSAR models for hazard identification and labelling of eye irritating chemicals.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Geerts, L; Adriaens, E; Alépée, N; Guest, R; Willoughby, J A; Kandarova, H; Drzewiecka, A; Fochtman, P; Verstraelen, S; Van Rompay, A R</p> <p>2018-06-01</p> <p>Assessment of ocular irritation is a regulatory requirement in safety evaluation of industrial and consumer products. Although a number of in vitro ocular irritation assays exist, none are capable of fully categorizing chemicals as stand-alone assays. Therefore, the CEFIC-LRI-AIMT6-VITO <span class="hlt">CON</span>4EI (CONsortium for in vitro Eye Irritation testing strategy) project was developed to assess the reliability of eight in vitro test methods and computational models as well as establishing an optimal tiered-testing strategy. For three computational models (Toxtree, and Case Ultra EYE_DRAIZE and EYE_IRR) performance parameters were calculated. Coverage ranged from 15 to 58%. Coverage was 2 to 3.4 times higher for liquids than for solids. The lowest number of false positives (5%) was reached with EYE_IRR; this model however also gave a high number of false negatives (46%). The lowest number of false negatives (25%) was seen with Toxtree; for liquids Toxtree predicted the lowest number of false negatives (11%), for solids EYE_DRAIZE did (17%). It can be concluded that the training sets should be enlarged with high quality data. The tested models are not yet sufficiently powerful for stand-alone evaluations, but that they can surely become of value in an integrated weight-of-evidence approach in hazard assessment. Copyright © 2017 Elsevier Ltd. All rights reserved.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3932546','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3932546"><span>Estereotipos Sexuales y su Relación <span class="hlt">con</span> Conductas Sexuales Riesgosas1,2,3</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Pérez-Jiménez, David; Orengo-Aguayo, Rosaura E.</p> <p>2012-01-01</p> <p>Resumen Los estereotipos sexuales son creencias generalmente aceptadas y poco cuestionadas que podrían contribuir a cómo los hombres y las mujeres debemos expresar nuestra sexualidad. Los objetivos de este estudio eran identificar cuántos hombres y mujeres heterosexuales en Puerto Rico endosaban ciertos estereotipos acerca de la sexualidad masculina y femenina y explorar la relación entre el endoso de estos estereotipos sexuales y las actitudes hacia el condón masculino y su uso en relaciones sexuales vaginales Llevamos a cabo un estudio descriptivo-correlacional mediante el cual le administramos dos escalas, una sobre sexualidad masculina y otra sobre sexualidad femenina a un grupo de 429 personas heterosexuales. Encontramos que los hombres endosaron estereotipos sexuales masculinos y femeninos más que las mujeres y que estos tienden a tener una visión más conservadora respecto a la sexualidad femenina que la que tienen sobre su propia sexualidad. Las mujeres, por otra parte, tienden a ver su propia sexualidad y la sexualidad masculina en términos menos estereotipados y más equitativos. También encontramos que a mayor endoso de creencias tradicionales sobre la sexualidad masculina y femenina, peor la actitud hacia el uso del condón masculino. Sin embargo, el endosar estereotipos sexuales masculinos y/o femeninos no se relacionó <span class="hlt">con</span> el uso del condón. Estos hallazgos contradicen la literatura que sugiere que estos estereotipos sexuales y de género resultan en conductas sexuales de alto riesgo, lo cual tiene implicaciones importantes para el desarrollo e implementación de programas de prevención. PMID:24575164</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/servlets/purl/1095442','SCIGOV-STC'); return false;" href="https://www.osti.gov/servlets/purl/1095442"><span>Characterization Data Package for Containerized Sludge Samples Collected from Engineered Container SCS-<span class="hlt">CON</span>-210</span></a></p> <p><a target="_blank" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a></p> <p>Fountain, Matthew S.; Fiskum, Sandra K.; Baldwin, David L.</p> <p></p> <p>This data package contains the K Basin sludge characterization results obtained by Pacific Northwest National Laboratory during processing and analysis of four sludge core samples collected from Engineered Container SCS-<span class="hlt">CON</span>-210 in 2010 as requested by CH2M Hill Plateau Remediation Company. Sample processing requirements, analytes of interest, detection limits, and quality control sample requirements are defined in the KBC-33786, Rev. 2. The core processing scope included reconstitution of a sludge core sample distributed among four to six 4-L polypropylene bottles into a single container. The reconstituted core sample was then mixed and subsampled to support a variety of characterization activities. Additionalmore » core sludge subsamples were combined to prepare a container composite. The container composite was fractionated by wet sieving through a 2,000 micron mesh and a 500-micron mesh sieve. Each sieve fraction was sampled to support a suite of analyses. The core composite analysis scope included density determination, radioisotope analysis, and metals analysis, including the Waste Isolation Pilot Plant Hazardous Waste Facility Permit metals (with the exception of mercury). The container composite analysis included most of the core composite analysis scope plus particle size distribution, particle density, rheology, and crystalline phase identification. A summary of the received samples, core sample reconstitution and subsampling activities, container composite preparation and subsampling activities, physical properties, and analytical results are presented. Supporting data and documentation are provided in the appendices. There were no cases of sample or data loss and all of the available samples and data are reported as required by the Quality Assurance Project Plan/Sampling and Analysis Plan.« less</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3164892','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3164892"><span>Document-Level Classification of CT Pulmonary Angiography Reports based on an Extension of the <span class="hlt">Con</span>Text Algorithm</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Chapman, Brian E.; Lee, Sean; Kang, Hyunseok Peter; Chapman, Wendy W.</p> <p>2011-01-01</p> <p>In this paper we describe an application called peFinder for document-level classification of CT pulmonary angiography reports. peFinder is based on a generalized version of the <span class="hlt">Con</span>Text algorithm, a simple text processing algorithm for identifying features in clinical report documents. peFinder was used to answer questions about the disease state (pulmonary emboli present or absent), the certainty state of the diagnosis (uncertainty present or absent), the temporal state of an identified pulmonary embolus (acute or chronic), and the technical quality state of the exam (diagnostic or not diagnostic). Gold standard answers for each question were determined from the consensus classifications of three human annotators. peFinder results were compared to naive Bayes’ classifiers using unigrams and bigrams. The sensitivities (and positive predictive values) for peFinder were 0.98(0.83), 0.86(0.96), 0.94(0.93), and 0.60(0.90) for disease state, quality state, certainty state, and temporal state respectively, compared to 0.68(0.77), 0.67(0.87), 0.62(0.82), and 0.04(0.25) for the naive Bayes’ classifier using unigrams, and 0.75(0.79), 0.52(0.69), 0.59(0.84), and 0.04(0.25) for the naive Bayes’ classifier using bigrams. PMID:21459155</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28133731','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28133731"><span>The Use of Laser Microdissection in Forensic Sexual Assault Casework: Pros and <span class="hlt">Cons</span> Compared to Standard Methods.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Costa, Sergio; Correia-de-Sá, Paulo; Porto, Maria J; Cainé, Laura</p> <p>2017-07-01</p> <p>Sexual assault samples are among the most frequently analyzed in a forensic laboratory. These account for almost half of all samples processed routinely, and a large portion of these cases remain unsolved. These samples often pose problems to traditional analytic methods of identification because they consist most frequently of cell mixtures from at least two contributors: the victim (usually female) and the perpetrator (usually male). In this study, we propose the use of current preliminary testing for sperm detection in order to determine the chances of success when faced with samples which can be good candidates to undergo analysis with the laser microdissection technology. Also, we used laser microdissection technology to capture fluorescently stained cells of interest differentiated by gender. Collected materials were then used for DNA genotyping with commercially available amplification kits such as Minifiler, Identifiler Plus, NGM, and Y-Filer. Both the methodology and the quality of the results were evaluated to assess the pros and <span class="hlt">cons</span> of laser microdissection compared with standard methods. Overall, the combination of fluorescent staining combined with the Minifiler amplification kit provided the best results for autosomal markers, whereas the Y-Filer kit returned the expected results regardless of the used method. © 2017 American Academy of Forensic Sciences.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2010AIPC.1218..445M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2010AIPC.1218..445M"><span>Status and Progress of a Fault Current Limiting Hts Cable to BE Installed in the <span class="hlt">con</span> EDISON Grid</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Maguire, J.; Folts, D.; Yuan, J.; Henderson, N.; Lindsay, D.; Knoll, D.; Rey, C.; Duckworth, R.; Gouge, M.; Wolff, Z.; Kurtz, S.</p> <p>2010-04-01</p> <p>In the last decade, significant advances in the performance of second generation (2G) high temperature superconducting wire have made it suitable for commercially viable applications such as electric power cables and fault current limiters. Currently, the U.S. Department of Homeland Security is co-funding the design, development and demonstration of an inherently fault current limiting HTS cable under the Hydra project with American Superconductor and Consolidated Edison. The cable will be approximately 300 m long and is being designed to carry 96 MVA at a distribution level voltage of 13.8 kV. The underground cable will be installed and energized in New York City. The project is led by American Superconductor teamed with <span class="hlt">Con</span> Edison, Ultera (Southwire and nkt cables joint venture), and Air Liquide. This paper describes the general goals, design criteria, status and progress of the project. Fault current limiting has already been demonstrated in 3 m prototype cables, and test results on a 25 m three-phase cable will be presented. An overview of the concept of a fault current limiting cable and the system advantages of this unique type of cable will be described.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4181712','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4181712"><span>Aceptabilidad del diagnóstico rápido casero para HIV entre hombres gay y otros hombres que tienen sexo <span class="hlt">con</span> hombres (G&HSH) de la Ciudad de Buenos Aires</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Balán, Iván C.; Carballo-Diéguez, Alex; Marone, Rubén O.; Pando, María A.; Barreda, Victoria; Ávila, María M.</p> <p>2011-01-01</p> <p>Resumen El uso del diagnóstico rápido para HIV en Argentina, así como otros países de Latinoamérica, ha sido limitado hasta el momento. Este trabajo reporta los resultados provenientes de un estudio cualitativo realizado entre hombres gays y otros hombres que tienen sexo <span class="hlt">con</span> hombres (G&HSH) de la Ciudad de Buenos Aires, Argentina. El objetivo principal del mismo fue conocer las ventajas y desventajas que los hombres G&HSH perciben en relación al diagnóstico rápido casero para HIV. Se realizaron ocho grupos focales <span class="hlt">con</span> 73 participantes en los cuales se discutió acerca de las ventajas y desventajas del uso de los diagnósticos rápidos. Las respuestas fueron codificadas utilizando un programa para análisis de datos cualitativos (NVivo) y analizadas temáticamente. Los participantes describieron numerosas ventajas sobre el uso del diagnóstico rápido casero, aunque algunos reportaron importantes preocupaciones dentro de las cuales se destaca la posibilidad de impulsos suicidas si alguien recibe un resultado positivo estando solo. En términos generales se observó una gran aceptabilidad para el uso del diagnóstico rápido si el mismo es realizado por personal de salud en lugares acondicionados para este fin. PMID:25284951</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li class="active"><span>22</span></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_22 --> <div id="page_23" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li class="active"><span>23</span></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li><a href="#" onclick='return showDiv("page_25");'>25</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="441"> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25284951','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25284951"><span>Aceptabilidad del diagnóstico rápido casero para HIV entre hombres gay y otros hombres que tienen sexo <span class="hlt">con</span> hombres (G&HSH) de la Ciudad de Buenos Aires.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Balán, Iván C; Carballo-Diéguez, Alex; Marone, Rubén O; Pando, María A; Barreda, Victoria; Avila, María M</p> <p>2011-03-01</p> <p>El uso del diagnóstico rápido para HIV en Argentina, así como otros países de Latinoamérica, ha sido limitado hasta el momento. Este trabajo reporta los resultados provenientes de un estudio cualitativo realizado entre hombres gays y otros hombres que tienen sexo <span class="hlt">con</span> hombres (G&HSH) de la Ciudad de Buenos Aires, Argentina. El objetivo principal del mismo fue conocer las ventajas y desventajas que los hombres G&HSH perciben en relación al diagnóstico rápido casero para HIV. Se realizaron ocho grupos focales <span class="hlt">con</span> 73 participantes en los cuales se discutió acerca de las ventajas y desventajas del uso de los diagnósticos rápidos. Las respuestas fueron codificadas utilizando un programa para análisis de datos cualitativos (NVivo) y analizadas temáticamente. Los participantes describieron numerosas ventajas sobre el uso del diagnóstico rápido casero, aunque algunos reportaron importantes preocupaciones dentro de las cuales se destaca la posibilidad de impulsos suicidas si alguien recibe un resultado positivo estando solo. En términos generales se observó una gran aceptabilidad para el uso del diagnóstico rápido si el mismo es realizado por personal de salud en lugares acondicionados para este fin.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.fs.usda.gov/treesearch/pubs/42383','TREESEARCH'); return false;" href="https://www.fs.usda.gov/treesearch/pubs/42383"><span>Modélisation des <span class="hlt">cons</span>équences possibles de la future demande bioénergétique mondiale pour le bois et les forêts en France</span></a></p> <p><a target="_blank" href="http://www.fs.usda.gov/treesearch/">Treesearch</a></p> <p>Joseph Buongiorno; Ronald Raunikar; Shusuai Zhu</p> <p>2011-01-01</p> <p>L’accroissement de la demande mondiale et du coût correspondant de l’énergie a conduit à de nombreuses propositions pour augmenter l’utilisation de la biomasse renouvelable. Une étude récente (Raunikar et al., 2010) a examiné les <span class="hlt">cons</span>équences mondiales pour le bois et pour les forêts de la demande en bioénergie impliquée par les scénarios du Groupe d’experts...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/16392895','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/16392895"><span>Detection of gonococcal infection : pros and <span class="hlt">cons</span> of a rapid test.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Vickerman, Peter; Peeling, Rosanna W; Watts, Charlotte; Mabey, David</p> <p>2005-01-01</p> <p> populations with high sexual activity and/or low return rates. Unfortunately, however, most of the rapid tests currently available are immunoassays that are quite expensive and involve many steps, which limit their current usefulness. In summary, the pros and <span class="hlt">cons</span> of using a rapid test are dependent on the setting. Culture or NAATs remain the best choice in an ideal setting. However, in settings where laboratory facilities are not available, or in high-risk populations where return rates are low, rapid tests may be the most effective way of diagnosing gonorrhea. Their optimal use in these settings requires the development of simpler and cheaper rapid tests.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/21295130','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/21295130"><span>"Plantas <span class="hlt">con</span> madre": plants that teach and guide in the shamanic initiation process in the East-Central Peruvian Amazon.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Jauregui, X; Clavo, Z M; Jovel, E M; Pardo-de-Santayana, M</p> <p>2011-04-12</p> <p>We present and discuss a particular group of plants used by a diversity of healers in the initiation process and apprenticeship of traditional medicine, as practiced by Amazonian societies in East-Central Peru. Often, these plants are locally called plantas <span class="hlt">con</span> madre (plants with a mother), and are thought to guide initiates in the process of seeking sacred knowledge, learning about plant usage, and understanding traditional medicine practices. We illustrate the diversity of plants used in the apprenticeship and practice of traditional medicine, and nurture the discussion to better understand the terminology used by Indigenous healers to describe plant uses and their practices. The study was conducted between 2003 and 2008 with the participation of 29 curanderos (healers; 23 men, 6 women), 3 apprentices and 4 herbalists. The participants belonged to four ethnic groups: 17 Mestizos, 15 Shipibo-Konibo, 1 Ashaninka, and 1 Matsiguenga; a Spanish apprentice and an Italian herbalist were also included in the study. The field data were collected using semi-structured interviews, participant observation, and the witnessing of numerous healing sessions. Oral informed consent was obtained from each participant. We identified 55 plant species belonging to 26 botanical families, which are used in initiation processes and apprenticeships of traditional medicine. This group of plants is administered under strict conditions during training and healing sessions called dietas (shamanic diets), with the supervision of one or more maestros curanderos (master healers). We observed that during the shamanic diets, maestros curanderos administered plants depending on the teachings or tools he/she was passing on, and were based on a particular sequence during the initiation process: (I) purification and cleansing species; (II) sensitivity and intuition; (III) strengthening; and (IV) protection and defence. Traditional healers continue to be a primary source of health care for the majority</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22233447','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22233447"><span>Expansion of antimonato polyoxovanadates with transition metal complexes: (<span class="hlt">Co(N</span>3C5H15)2)2[{<span class="hlt">Co(N</span>3C5H15)2}V15Sb6O42(H2O)]·5H2O and (Ni(N3C5H15)2)2[{Ni(N3C5H15)2}V15Sb6O42(H2O)]·8H2O.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Antonova, Elena; Näther, Christian; Kögerler, Paul; Bensch, Wolfgang</p> <p>2012-02-20</p> <p>Two new polyoxovanadates (<span class="hlt">Co(N</span>(3)C(5)H(15))(2))(2)[{<span class="hlt">Co(N</span>(3)C(5)H(15))(2)}V(15)Sb(6)O(42)(H(2)O)]·5H(2)O (1) and (Ni(N(3)C(5)H(15))(2))(2)[{Ni(N(3)C(5)H(15))(2)}V(15)Sb(6)O(42)(H(2)O)]·8H(2)O (2) (N(3)C(5)H(15) = N-(2-aminoethyl)-1,3-propanediamine) were synthesized under solvothermal conditions and structurally characterized. In both structures the [V(15)Sb(6)O(42)(H(2)O)](6-) shell displays the main structural motif, which is strongly related to the {V(18)O(42)} archetype cluster. Both compounds crystallize in the triclinic space group P1 with a = 14.3438(4), b = 16.6471(6), c = 18.9186(6) Å, α = 87.291(3)°, β = 83.340(3)°, γ = 78.890(3)°, and V = 4401.4(2) Å(3) (1) and a = 14.5697(13), b = 15.8523(16), c = 20.2411(18) Å, α = 86.702(11)°, β = 84.957(11)°, γ = 76.941(11)°, and V = 4533.0(7) Å(3) (2). In the structure of 1 the [V(15)Sb(6)O(42)(H(2)O)](6-) cluster anion is bound to a [<span class="hlt">Co(N</span>(3)C(5)H(15))(2)](2+) complex via a terminal oxygen atom. In the Co(2+)-centered complex, one of the amine ligands coordinates in tridentate mode and the second one in bidentate mode to form a strongly distorted <span class="hlt">CoN</span>(5)O octahedron. Similarly, in compound 2 an analogous NiN(5)O complex is joined to the [V(15)Sb(6)O(42)(H(2)O)](6-) anion via the same attachment mode. A remarkable difference between the two compounds is the orientation of the noncoordinated propylamine group leading to intermolecular Sb···O contacts in 1 and to Sb···N interactions in 2. In the solid-state lattices of 1 and 2, two additional [M(N(3)C(5)H(15))(2)](2+) complexes act as countercations and are located between the [{M(N(3)C(5)H(15))(2)}V(15)Sb(6)O(42)(H(2)O)](4-) anions. Between the anions and cations strong N-H···O hydrogen bonds are observed. In both compounds the clusters are stacked along the b axis in an ABAB fashion with cations and water molecules occupying the space between the clusters. Magnetic characterization demonstrates that the Ni(2+) and Co(2+) cations do not</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2003BAAA...46...12M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2003BAAA...46...12M"><span>Distribución espacial de órbitas <span class="hlt">con</span> diferentes grados de caoticidad en modelos autoconsistentes de satélites galácticos</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Muzzio, J. C.; Mosquera, M.</p> <p></p> <p>En trabajos anteriores (Carpintero et al., Cel. Mech. Dynam. Astron. 85, 247, 2003), mostramos que las órbitas caóticas son muy importantes en los satélites galácticos. Sin embargo, los únicos modelos autoconsistentes de los que se disponía para ellos eran los de Heggie-Ramamani, cuya función de distribución depende sólo de la energía por lo que no mostraban diferencias entre las distribuciones de sus órbitas regulares y caóticas. Ahora, mediante una aproximación cuadrupolar, hemos logrado construir modelos autoconsistentes de satélites galácticos <span class="hlt">con</span> distribuciones de velocidades anisotrópicas (lo que indica que sus funciones de distribución no dependen sólo de la energía) y hemos logrado revelar las diferencias entre las estructuras espaciales de las órbitas de distinta caoticidad.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/21459155','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/21459155"><span>Document-level classification of CT pulmonary angiography reports based on an extension of the <span class="hlt">Con</span>Text algorithm.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Chapman, Brian E; Lee, Sean; Kang, Hyunseok Peter; Chapman, Wendy W</p> <p>2011-10-01</p> <p>In this paper we describe an application called peFinder for document-level classification of CT pulmonary angiography reports. peFinder is based on a generalized version of the <span class="hlt">Con</span>Text algorithm, a simple text processing algorithm for identifying features in clinical report documents. peFinder was used to answer questions about the disease state (pulmonary emboli present or absent), the certainty state of the diagnosis (uncertainty present or absent), the temporal state of an identified pulmonary embolus (acute or chronic), and the technical quality state of the exam (diagnostic or not diagnostic). Gold standard answers for each question were determined from the consensus classifications of three human annotators. peFinder results were compared to naive Bayes' classifiers using unigrams and bigrams. The sensitivities (and positive predictive values) for peFinder were 0.98(0.83), 0.86(0.96), 0.94(0.93), and 0.60(0.90) for disease state, quality state, certainty state, and temporal state respectively, compared to 0.68(0.77), 0.67(0.87), 0.62(0.82), and 0.04(0.25) for the naive Bayes' classifier using unigrams, and 0.75(0.79), 0.52(0.69), 0.59(0.84), and 0.04(0.25) for the naive Bayes' classifier using bigrams. Copyright © 2011 Elsevier Inc. All rights reserved.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27212150','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27212150"><span>Could simvastatin be considered as a potential therapy for chronic lung diseases? A debate on the pros and <span class="hlt">cons</span>.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Tulbah, Alaa S; Ong, Hui Xin; Colombo, Paolo; Young, Paul M; Traini, Daniela</p> <p>2016-10-01</p> <p>Simvastatin (SV) is a drug from the statin class, currently used orally as an anti-cholesterolemic drug. It inhibits the 3-hydroxy-3-methyl-glutaryl-Coenzyme A (HMG-CoA) reductase to reduce cholesterol synthesis. Recently, it has been found that SV also has several other protective pharmacological actions unrelated to its anti-cholesterol effects that might be beneficial in the treatment of chronic airway diseases. This review summarizes the evidence relating to SV as a potential anti-inflammatory, anti-oxidant and muco-inhibitory agent, administered both orally and via pulmonary inhalation, and discusses its pro and <span class="hlt">cons</span>. Evidence could potentially be used to support the delivery of SV as inhaled formulation for the treatment of chronic respiratory diseases. The use of SV as anti-inflammatory, anti-oxidant and muco-inhibitory agent for drug delivery to the lung is promising. Inhaled SV formulations could allow the delivery profile to be customized and optimized to take advantage of the rapid onset of action, low systemic side effect and improved physico-chemical stability. This treatment could potentially to be used clinically for the localized treatment of lung diseases where inflammation and oxidative stress production is present.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29696767','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29696767"><span>Experimental Identification of the Active Site in the Heteronuclear Redox Couples [AlVOx ]+. /<span class="hlt">CO/N</span>2 O (x=3, 4) by Gas-Phase IR Spectroscopy.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Debnath, Sreekanta; Knorke, Harald; Schöllkopf, Wieland; Zhou, Shaodong; Asmis, Knut R; Schwarz, Helmut</p> <p>2018-06-18</p> <p>Cryogenic ion vibrational spectroscopy was used in combination with electronic structure calculations to identify the active site in the oxygen atom transfer reaction [AlVO 4 ] +. +CO→[AlVO 3 ] +. +CO 2 . Infrared photodissociation spectra of messenger-tagged heteronuclear clusters demonstrate that in contrast to [AlVO 4 ] +. , [AlVO 3 ] +. is devoid of a terminal Al-O t unit while the terminal V=O t group remains intact. Thus it is the Al-O t moiety that forms the active site in the [AlVO x ] +. /<span class="hlt">CO/N</span> 2 O (x=3, 4) redox couples, which is in line with theoretical predictions. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28480138','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28480138"><span>v<span class="hlt">Con</span>TACT: an iVirus tool to classify double-stranded DNA viruses that infect Archaea and Bacteria.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Bolduc, Benjamin; Jang, Ho Bin; Doulcier, Guilhem; You, Zhi-Qiang; Roux, Simon; Sullivan, Matthew B</p> <p>2017-01-01</p> <p>Taxonomic classification of archaeal and bacterial viruses is challenging, yet also fundamental for developing a predictive understanding of microbial ecosystems. Recent identification of hundreds of thousands of new viral genomes and genome fragments, whose hosts remain unknown, requires a paradigm shift away from traditional classification approaches and towards the use of genomes for taxonomy. Here we revisited the use of genomes and their protein content as a means for developing a viral taxonomy for bacterial and archaeal viruses. A network-based analytic was evaluated and benchmarked against authority-accepted taxonomic assignments and found to be largely concordant. Exceptions were manually examined and found to represent areas of viral genome 'sequence space' that are under-sampled or prone to excessive genetic exchange. While both cases are poorly resolved by genome-based taxonomic approaches, the former will improve as viral sequence space is better sampled and the latter are uncommon. Finally, given the largely robust taxonomic capabilities of this approach, we sought to enable researchers to easily and systematically classify new viruses. Thus, we established a tool, v<span class="hlt">Con</span>TACT, as an app at iVirus, where it operates as a fast, highly scalable, user-friendly app within the free and powerful CyVerse cyberinfrastructure.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5419219','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5419219"><span>v<span class="hlt">Con</span>TACT: an iVirus tool to classify double-stranded DNA viruses that infect Archaea and Bacteria</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Doulcier, Guilhem; You, Zhi-Qiang; Roux, Simon</p> <p>2017-01-01</p> <p>Taxonomic classification of archaeal and bacterial viruses is challenging, yet also fundamental for developing a predictive understanding of microbial ecosystems. Recent identification of hundreds of thousands of new viral genomes and genome fragments, whose hosts remain unknown, requires a paradigm shift away from traditional classification approaches and towards the use of genomes for taxonomy. Here we revisited the use of genomes and their protein content as a means for developing a viral taxonomy for bacterial and archaeal viruses. A network-based analytic was evaluated and benchmarked against authority-accepted taxonomic assignments and found to be largely concordant. Exceptions were manually examined and found to represent areas of viral genome ‘sequence space’ that are under-sampled or prone to excessive genetic exchange. While both cases are poorly resolved by genome-based taxonomic approaches, the former will improve as viral sequence space is better sampled and the latter are uncommon. Finally, given the largely robust taxonomic capabilities of this approach, we sought to enable researchers to easily and systematically classify new viruses. Thus, we established a tool, v<span class="hlt">Con</span>TACT, as an app at iVirus, where it operates as a fast, highly scalable, user-friendly app within the free and powerful CyVerse cyberinfrastructure. PMID:28480138</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/servlets/purl/1368218','SCIGOV-STC'); return false;" href="https://www.osti.gov/servlets/purl/1368218"><span>v<span class="hlt">Con</span>TACT: an iVirus tool to classify double-stranded DNA viruses that infect Archaea and Bacteria</span></a></p> <p><a target="_blank" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a></p> <p>Bolduc, Benjamin; Jang, Ho Bin; Doulcier, Guilhem</p> <p></p> <p>Taxonomic classification of archaeal and bacterial viruses is challenging, yet also fundamental for developing a predictive understanding of microbial ecosystems. Recent identification of hundreds of thousands of new viral genomes and genome fragments, whose hosts remain unknown, requires a paradigm shift away from traditional classification approaches and towards the use of genomes for taxonomy. Here we revisited the use of genomes and their protein content as a means for developing a viral taxonomy for bacterial and archaeal viruses. A network-based analytic was evaluated and benchmarked against authority-accepted taxonomic assignments and found to be largely concordant. Exceptions were manually examined andmore » found to represent areas of viral genome ‘sequence space’ that are under-sampled or prone to excessive genetic exchange. While both cases are poorly resolved by genome-based taxonomic approaches, the former will improve as viral sequence space is better sampled and the latter are uncommon. Finally, given the largely robust taxonomic capabilities of this approach, we sought to enable researchers to easily and systematically classify new viruses. Thus, we established a tool, v<span class="hlt">Con</span>TACT, as an app at iVirus, where it operates as a fast, highly scalable, user-friendly app within the free and powerful CyVerse cyberinfrastructure.« less</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018JMMM..451..360B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018JMMM..451..360B"><span>Spin-orbit coupling effect on structural and magnetic properties of <span class="hlt">Con</span>Rh13-n (n = 0-13) clusters</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Bai, Xi; Lv, Jin; Zhang, Fu-Qiang; Jia, Jian-Feng; Wu, Hai-Shun</p> <p>2018-04-01</p> <p>The effect of spin-orbit interaction on the structures and magnetism of <span class="hlt">Con</span>Rh13-n (n = 0-13) clusters have been systematically investigated by using the spin-orbit coupling (SOC) implementation of the density functional theory (DFT). The results calculated without SOC (NSOC) show that Rh13 prefers the double simple-cubic configuration, and icosahedron is the favorable structure for n = 1-9, while n ≥ 10, clusters favor the hexagonal bilayer structure. The inclusion of SOC in calculation does not change the geometries of clusters. Compared with that in NSOC calculation, although the binding energy per atom in clusters with same composition decreases in SOC calculation, the relative stability of clusters with different compositions does not change. An interesting result is that the spin moments of clusters for n = 1-9 are almost constant (21 μB). Spin-orbit interaction recovers orbital moment and its anisotropy by removing crystal-field effect in calculation. The destruction of bonding symmetry and relaxation of bonding account for high anisotropies of orbital moments in Co11Rh2 and CoRh12 clusters. With atomic composition (Co/Rh) around 4/9-5/8 and 9/4, the Co-Rh clusters exhibit high magnetic anisotropy energies.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24794738','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24794738"><span>Special funding schemes for innovative medical devices in French hospitals: the pros and <span class="hlt">cons</span> of two different approaches.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Martelli, Nicolas; van den Brink, Hélène</p> <p>2014-07-01</p> <p>Financing innovative medical devices is an important challenge for national health policy makers, and a crucial issue for hospitals. However, when innovative medical devices are launched on the European market there is generally little clinical evidence regarding both efficacy and safety, both because of the flaws in the European system for regulating such devices, and because they are at an early stage of development. To manage the uncertainty surrounding the reimbursement of innovation, several European countries have set up temporary funding schemes to generate evidence about the effectiveness of devices. This article explores two different French approaches to funding innovative in-hospital devices and collecting supplementary data: the coverage with evidence development (CED) scheme introduced under Article L. 165-1-1 of the French Social Security Code; and national programs for hospital-based research. We discuss pros and <span class="hlt">cons</span> of both approaches in the light of CED policies in Germany and the UK. The CED policies for devices share common limitations. Thus, transparency of CED processes should be enhanced and decisions need to be made in a timely way. Finally, we think that closer collaboration between manufacturers, health authorities and hospitals is essential to make CED policies more operational. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/pages/biblio/1368218-vcontact-ivirus-tool-classify-double-stranded-dna-viruses-infect-archaea-bacteria','SCIGOV-DOEP'); return false;" href="https://www.osti.gov/pages/biblio/1368218-vcontact-ivirus-tool-classify-double-stranded-dna-viruses-infect-archaea-bacteria"><span>v<span class="hlt">Con</span>TACT: an iVirus tool to classify double-stranded DNA viruses that infect Archaea and Bacteria</span></a></p> <p><a target="_blank" href="http://www.osti.gov/pages">DOE PAGES</a></p> <p>Bolduc, Benjamin; Jang, Ho Bin; Doulcier, Guilhem; ...</p> <p>2017-05-03</p> <p>Taxonomic classification of archaeal and bacterial viruses is challenging, yet also fundamental for developing a predictive understanding of microbial ecosystems. Recent identification of hundreds of thousands of new viral genomes and genome fragments, whose hosts remain unknown, requires a paradigm shift away from traditional classification approaches and towards the use of genomes for taxonomy. Here we revisited the use of genomes and their protein content as a means for developing a viral taxonomy for bacterial and archaeal viruses. A network-based analytic was evaluated and benchmarked against authority-accepted taxonomic assignments and found to be largely concordant. Exceptions were manually examined andmore » found to represent areas of viral genome ‘sequence space’ that are under-sampled or prone to excessive genetic exchange. While both cases are poorly resolved by genome-based taxonomic approaches, the former will improve as viral sequence space is better sampled and the latter are uncommon. Finally, given the largely robust taxonomic capabilities of this approach, we sought to enable researchers to easily and systematically classify new viruses. Thus, we established a tool, v<span class="hlt">Con</span>TACT, as an app at iVirus, where it operates as a fast, highly scalable, user-friendly app within the free and powerful CyVerse cyberinfrastructure.« less</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015EGUGA..17.9550J','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015EGUGA..17.9550J"><span>Petrological and geochemical studies of mantle xenoliths from La Palma, Canary Islands</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Janisch, Astrid; Ntaflos, Theodoros</p> <p>2015-04-01</p> <p>La Palma is the second youngest island, after El <span class="hlt">Hierro</span>, of the Canary archipelago. The archipelago consists of seven large islands, forming an east-west-trending island chain, and several seamounts. All together they form a volcanic belt of around 800 km length and 450 km width, which presumably comprises roughly the Canary hotspot. The islands are located off the western coast of Morocco, Africa. The distance ranges from 100 km to 500 km. Concurrently with the distance, subaerial volcanism age progresses from the oldest lava in the east to the youngest in the west of the archipelago. Presently, La Palma is in the shield building stage of growth (alongside with El <span class="hlt">Hierro</span> and Tenerife) and is furthermore the fastest growing island of the Canary archipelago. Historical volcanic eruptions are restricted on the younger islands, La Palma and El <span class="hlt">Hierro</span>, with the last eruption at the south end of La Palma in 1971. Mantle xenoliths described in this work were collected at the slopes of San Antonio Volcano, Fuencaliente, brought to the surface during the 1677/1678 eruption. The mantle xenolith collection comprises sp-lherzolites, sp-harzburgites and pyroxenites. The texture can be distinguished between coarse-grained matrix and fine-grained veins in various thicknesses, mostly with olivine and pyroxene but also with amphibole, phlogopite as well as apatite. Mineral analyses reveal the existence of primary and secondary ol, cpx and opx. Primary ol has Fo contents of 89.2 to 91.7 and NiO ranging from 0.3 to 0.45 wt.%, whereas secondary ol show Fo values of 78.4 to 91.9 but with NiO below 0.3 wt.%. Primary cpx are predominantly Cr-Diopsides with En48.7-51.9-Wo43.5-44.3-Fs4.1-4.9 and Mg# of 91.5 to 92.4. Secondary cpx, primarily Ti-Augit, display En36.7-44.4-Wo47.7-49.6-Fs6.7-13.0 and Mg# of 75.3 to 90.8. Primary opx compositions are in range of En89.3-90.6-Wo1.3-1.5-Fs8.1-9.3 with Mg# between 90.7 and 92.0. Secondary opx exhibit En88.7-89.2-Wo1.7-1.9-Fs9.1-9.5 and Mg# of 90</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3422096','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3422096"><span>Iliac crest autograft versus alternative constructs for anterior cervical spine surgery: Pros, <span class="hlt">cons</span>, and costs</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Epstein, Nancy E.</p> <p>2012-01-01</p> <p>Background: Grafting choices available for performing anterior cervical diskectomy/fusion (ACDF) procedures have become a major concern for spinal surgeons, and their institutions. The “gold standard”, iliac crest autograft, may still be the best and least expensive grafting option; it deserves to be reassessed along with the pros, <span class="hlt">cons</span>, and costs for alternative grafts/spacers. Methods: Although single or multilevel ACDF have utilized iliac crest autograft for decades, the implant industry now offers multiple alternative grafting and spacer devices; (allografts, cages, polyether-etherketone (PEEK) amongst others). While most studies have focused on fusion rates and clinical outcomes following ACDF, few have analyzed the “value-added” of these various constructs (e.g. safety/efficacy, risks/complications, costs). Results: The majority of studies document 95%-100% fusion rates when iliac crest autograft is utilized to perform single level ACDF (X-ray or CT confirmed at 6-12 postoperative months). Although many allograft studies similarly quote 90%-100% fusion rates (X-ray alone confirmed at 6-12 postoperative months), a recent “post hoc analysis of data from a prospective multicenter trial” (Riew KD et. al., CSRS Abstract Dec. 2011; unpublished) revealed a much higher delayed fusion rate using allografts at one year 55.7%, 2 years 87%, and four years 92%. Conclusion: Iliac crest autograft utilized for single or multilevel ACDF is associated with the highest fusion, lowest complication rates, and significantly lower costs compared with allograft, cages, PEEK, or other grafts. As spinal surgeons and institutions become more cost conscious, we will have to account for the “value added” of these increasingly expensive graft constructs. PMID:22905321</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2013PhDT........23D','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2013PhDT........23D"><span>Concepciones Alternativas de "Fotosintesis" en estudiantes Universitarios del curso basico de Biologia y posibles correcciones <span class="hlt">con</span> el Modelo Educativo MODEF</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>De Jesus Roman, Sandra</p> <p></p> <p>Concepciones Alternativas de Fotosíntesis en estudiantes Universitariosdel curso básico de Biología y posibles correcciones <span class="hlt">con</span> el Modelo Educativo MODEF El modelo educativo para la enseñanza de Fotosíntesis (MODEF) se implantó para trabajar el problema de las concepciones alternativas (CA) en un curso de Biología General. Se evaluaron los resultados en cuanto al logro del aprendizaje significativo. La pregunta central de la investigación fue: ¿Cómo aporta el modelo educativo en la didáctica y comprensión del tema de fotosíntesis? Se efectuó una investigación acción <span class="hlt">con</span> una fase cuantitativa y una cualitativa. Para la fase cuantitativa se elaboró una prueba para determinar las concepciones alternativas, se validó y se sometió a los estudiantes que participaron en el estudio antes y después de ofrecer la unidad de metabolismo celular. Los participantes eran estudiantes de primer año de la Universidad de Puerto Rico en Bayamón (UPRB). Se llevó a cabo un análisis de consistencia interna de la prueba mediante el método Alfa de Cronbach. Se analizaron las contestaciones a cada pregunta mediante la prueba de Ji cuadrado de contingencia, se efectuó la prueba de t y el coeficiente r de Pearson. La fase cualitativa incluyó la observación participativa de la investigadora- profesora, las reflexiones de los estudiantes y la información de las entrevistas semi-estructuradas que se realizaron a tres estudiantes del curso. El análisis se llevó a cabo mediante el Modelo de Wolcott. Se trabajaron diez CA de las cuales siete fueron corregidas mediante el Modelo MODEF. Las actividades más importantes para el proceso de aprendizaje incluyeron el trabajo de investigación o búsqueda de información para hacer una presentación digital, la elaboración de tablas, los mapas de conceptos, el uso de visuales o videos y las analogías para explicar conceptos o procesos. En conclusión: se recomienda el uso del Modelo MODEF para la discusión del tema de</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/19629346','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/19629346"><span>[GST genes expression as prognostic factor in papillary thyroid cancer].</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Gonçalves, Antonio Jose; Monte, Osmar; Morari, Eliane Cristina; Ward, Laura Sterian; Nakasako, Diana Shimoda; Nieto, Juliana; Nakai, Marianne Yumi</p> <p>2009-01-01</p> <p>Analyze the relationship between the AMES classification and molecular factors from Glutation-S-Transferase System, specifically the GSTT1 and GSTM1 in patients with well differentiated thyroid cancer. Samples of thyroid tissue of 66 patients with papillary thyroid carcinoma were obtained (53 women and 13 men). Patients were divided in two groups (high and low risk) according to the AMES classification. In each group, presence of the null genotype of both GST enzymes system was studied. These results were compared with the AMES classification. Samples were obtained in the operating room immediately after thyroidectomy, placed in cryotubes, immersed in liquid nitrogen and stored in a freezer at -80 masculineC. DNA of this enzymes was extracted by the <span class="hlt">fenol</span>-cloroformium method. There were 17 high risk patients and 49 low risk patients. The null genotype of the high risk group was 5.8% and in the other group was 6.1%. There was no relationship between absence of genes GSTT1 and GSTM1 and prognosis of the papillary thyroid carcinoma when compared to the AMES classifications.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017AGUFM.V23C0494L','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017AGUFM.V23C0494L"><span>Historical volcanic eruptions in the Canary Islands, tephra composition, and insights into the crystal cargo of basaltic magmas</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Longpre, M. A.; Muller, J.; Beaudry, P.; Andronikides, A.; Felpeto, A.</p> <p>2017-12-01</p> <p>Since the 16th century, at least 13 volcanic eruptions have occurred in the Canary Islands that formed monogenetic cinder cones and lava flow fields: 2 on Lanzarote, 4 on Tenerife, 6 on La Palma, and 1 on the submarine flank of El <span class="hlt">Hierro</span>. Here we present a comprehensive new dataset of tephra composition for all 13 eruptions, comprising major and trace element data for bulk rocks and matrix glasses, as well as vesicularity and crystallinity measurements. In addition, we compile available volcanological and petrological information for specific eruptions, including estimates of lava flow area and volume. All lapilli samples show a vesicularity of 40-50 vol% and a vesicle-free crystallinity (crystals ≥ 250 µm) of 5-15 vol%. Modal mineralogy varies significantly between samples, typically consisting of olivine ± clinopyroxene ± Fe-Ti oxide ± plagioclase ± amphibole in different proportions. All but 2 tephras have basanite-tephrite bulk rock compositions. Lapilli from vents of the AD 1730-1736 Timanfaya eruption, Lanzarote, largely are basaltic, whereas the AD 1798 Chahorra eruption, Tenerife, produced phonotephrite tephra. These results are in agreement with published bulk lava flow data. Unsurprisingly, glass compositions are more evolved than bulk rocks and MgOglass is weakly positively correlated to MgObulk (MgOglass = 0.30*MgObulk + 2.11, R2 = 0.54). Both bulk rocks and glasses show strikingly similar multi-element diagram patterns, with strong enrichment relative to the bulk-silicate Earth and marked positive Nb and Ta and negative Pb anomalies — typical for ocean island basalts. Glass/bulk rock elemental ratios reveal systematic differences between samples that relate to their mineralogy; for example, Lanzarote tephras that lack significant clinopyroxene and Fe-Ti oxide crystals have higher Scglass/Scbulk and Vglass/Vbulk than Tenerife, La Palma and El <span class="hlt">Hierro</span> samples that typically contain these minerals. Among all elements, K and P display the greatest</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li class="active"><span>23</span></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li><a href="#" onclick='return showDiv("page_25");'>25</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_23 --> <div id="page_24" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li class="active"><span>24</span></li> <li><a href="#" onclick='return showDiv("page_25");'>25</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="461"> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015JVGR..308..127R','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015JVGR..308..127R"><span>Are volcanic seismic b-values high, and if so when?</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Roberts, Nick S.; Bell, Andrew F.; Main, Ian G.</p> <p>2015-12-01</p> <p>The Gutenberg-Richter exponent b is a measure of the relative proportion of large and small earthquakes. It is commonly used to infer material properties such as heterogeneity, or mechanical properties such as the state of stress from earthquake populations. It is 'well known' that the b-value tends to be high or very high for volcanic earthquake populations relative to b = 1 for those of tectonic earthquakes, and that b varies significantly with time during periods of unrest. We first review the supporting evidence from 34 case studies, and identify weaknesses in this argument due predominantly to small sample size, the narrow bandwidth of magnitude scales available, variability in the methods used to assess the minimum or cutoff magnitude Mc, and to infer b. Informed by this, we use synthetic realisations to quantify the effect of choice of the cutoff magnitude on maximum likelihood estimates of b, and suggest a new work flow for this choice. We present the first quantitative estimate of the error in b introduced by uncertainties in estimating Mc, as a function of the number of events and the b-value itself. This error can significantly exceed the commonly-quoted statistical error in the estimated b-value, especially for the case that the underlying b-value is high. We apply the new methods to data sets from recent periods of unrest in El <span class="hlt">Hierro</span> and Mount Etna. For El <span class="hlt">Hierro</span> we confirm significantly high b-values of 1.5-2.5 prior to the 10 October 2011 eruption. For Mount Etna the b-values are indistinguishable from b = 1 within error, except during the flank eruptions at Mount Etna in 2001-2003, when 1.5 < b < 2.0. For the time period analysed, they are rarely lower than b = 1. Our results confirm that these volcano-tectonic earthquake populations can have systematically high b-values, especially when associated with eruptions. At other times they can be indistinguishable from those of tectonic earthquakes within the total error. The results have significant</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/12623647','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/12623647"><span>Selenium and mercury concentrations in sweet and dry bottled wines from the Canary Islands, Spain.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Frías, S; Díaz, C; Conde, J E; Pérez Trujillo, J P</p> <p>2003-03-01</p> <p>The concentrations of selenium and mercury were determined by atomic absorption spectrophotometry in sweet and dry bottled wines from the Canary Islands, Spain. The concentrations of mercury ranged from 2.6 to 4.9 microg x l(-1) for sweet wines, and from 1.5 to 2.6 microg x l(-1) for dry wines, differences (p < 0.05) being observed according to the island of production and type of wine, but not with respect to vintage. The concentration of selenium varied between 1.0 and 2.0 microg x l(-1) for sweet wines, and between 0.6 and 1.6 microg x l(-1) for dry wines. Differences were found in the mean concentrations according to the type of wine. Dry wines produced in La Palma presented a higher (p < 0.05) mean content than those observed in the wines of El <span class="hlt">Hierro</span> and Lanzarote.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4570429','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4570429"><span>Use of Low-Cost Acquisition Systems with an Embedded Linux Device for Volcanic Monitoring</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Moure, David; Torres, Pedro; Casas, Benito; Toma, Daniel; Blanco, María José; Del Río, Joaquín; Manuel, Antoni</p> <p>2015-01-01</p> <p>This paper describes the development of a low-cost multiparameter acquisition system for volcanic monitoring that is applicable to gravimetry and geodesy, as well as to the visual monitoring of volcanic activity. The acquisition system was developed using a System on a Chip (SoC) Broadcom BCM2835 Linux operating system (based on DebianTM) that allows for the construction of a complete monitoring system offering multiple possibilities for storage, data-processing, configuration, and the real-time monitoring of volcanic activity. This multiparametric acquisition system was developed with a software environment, as well as with different hardware modules designed for each parameter to be monitored. The device presented here has been used and validated under different scenarios for monitoring ocean tides, ground deformation, and gravity, as well as for monitoring with images the island of Tenerife and ground deformation on the island of El <span class="hlt">Hierro</span>. PMID:26295394</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26295394','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26295394"><span>Use of Low-Cost Acquisition Systems with an Embedded Linux Device for Volcanic Monitoring.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Moure, David; Torres, Pedro; Casas, Benito; Toma, Daniel; Blanco, María José; Del Río, Joaquín; Manuel, Antoni</p> <p>2015-08-19</p> <p>This paper describes the development of a low-cost multiparameter acquisition system for volcanic monitoring that is applicable to gravimetry and geodesy, as well as to the visual monitoring of volcanic activity. The acquisition system was developed using a System on a Chip (SoC) Broadcom BCM2835 Linux operating system (based on DebianTM) that allows for the construction of a complete monitoring system offering multiple possibilities for storage, data-processing, configuration, and the real-time monitoring of volcanic activity. This multiparametric acquisition system was developed with a software environment, as well as with different hardware modules designed for each parameter to be monitored. The device presented here has been used and validated under different scenarios for monitoring ocean tides, ground deformation, and gravity, as well as for monitoring with images the island of Tenerife and ground deformation on the island of El <span class="hlt">Hierro</span>.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1998BAAA...42...22P','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1998BAAA...42...22P"><span>Relación masa-radio para estrellas enanas blancas y la interpretación de recientes mediciones hechas por Hipparcos</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Panei, J. A.; Althaus, L. G.; Benvenuto, O. G.</p> <p></p> <p>Recientes mediciones de la masa y el radio hechas por Hipparcos de las estrellas enanas blancas 40 Eri B y Procyon B (Shipman, H. & Provencal, J. - ApJ. 1998, 494, 759), sugieren un núcleo compuesto de <span class="hlt">hierro</span> para dichas estrellas, en lugar de carbono y oxígeno como predice la teoría standard de evolución estelar. Para interpretar estas observaciones, presentamos aquí, relaciones masa-radio para configuraciones degeneradas a temperatura finita para distintas composiciones químicas centrales. Para tal fin hemos calculado secuencias evolutivas de enanas blancas utilizando el código de evolución estelar, desarrollado en el Observatorio de La Plata. Dicho código resuelve las ecuaciones de estructura y evolución estelar mediante la técnica de relajación de Henyey, y esta basado en una descripción física muy detallada y actualizada.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28622405','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28622405"><span>Implementing a Randomized Controlled Trial through a Community-Academia Partnered Participatory Research: Arte <span class="hlt">con</span> Salud Research-Informed Intervention.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Noboa-Ortega, Patricia; Figueroa-Cosme, Wanda I; Feldman-Soler, Alana; Miranda-Díaz, Christine</p> <p>2017-06-01</p> <p>"Arte <span class="hlt">con</span> Salud" is an HIV/AIDS prevention intervention tailored for Puerto Rican women who have sex with men. The intervention curriculum was refined through a community-academic collaboration between Taller Salud, the UPRCayey Campus, and the UCC-School of Medicine, subsided in 2012-13 by PRCTRC. The collaboration has been crucial to validate the impact of using art as a tool to facilitate sexual negotiation skills and safer sexual practices among adult women have sex with men participating in HIV prevention education. This article describes the vision, valley, victory phases endured to establish a community-academia partnership based on the CPPR framework as an effective mean to implement a randomized controlled trial intervention (RCT). We also discuss the barriers, outcomes, and lessons learned from this partnership. Some of the identified solutions include: setting goals to secure funding, regular meetings, and the inclusion of undergraduate level students to assist in the implementation of the intervention. These solutions helped to build trust among the community and academic partners. As a result of this collaboration, a total of 86 participants were enrolled and 5 competitive research grants have been submitted. The community-academic collaboration was essential in order to build a solid research infrastructure that addresses the complexities of HIV prevention education among groups of Puerto Rican women.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28697962','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28697962"><span><span class="hlt">CON</span>4EI: EpiOcular™ Eye Irritation Test (EpiOcular™ EIT) for hazard identification and labelling of eye irritating chemicals.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Kandarova, H; Letasiova, S; Adriaens, E; Guest, R; Willoughby, J A; Drzewiecka, A; Gruszka, K; Alépée, Nathalie; Verstraelen, Sandra; Van Rompay, An R</p> <p>2018-06-01</p> <p>Assessment of the acute eye irritation potential is part of the international regulatory requirements for testing of chemicals. The objective of the <span class="hlt">CON</span>4EI project was to develop tiered testing strategies for eye irritation assessment. A set of 80 reference chemicals (38 liquids and 42 solids) was tested with eight different methods. Here, the results obtained with the EpiOcular™ Eye Irritation Test (EIT), adopted as OECD TG 492, are shown. The primary aim of this study was to evaluate of the performance of the test method to discriminate between chemicals not requiring classification for serious eye damage/eye irritancy (No Category) and chemicals requiring classification and labelling. In addition, the predictive capacity in terms of in vivo drivers of classification (i.e. corneal opacity, conjunctival redness and persistence at day 21) was investigated. EpiOcular™ EIT achieved a sensitivity of 97%, a specificity of 87% and accuracy of 95% and also confirmed its excellent reproducibility (100%) from the original validation. The assay was applicable to all chemical categories tested in this project and its performance was not limited to the particular driver of the classification. In addition to the existing prediction model for dichotomous categorization, a new prediction model for Cat 1 is suggested. Copyright © 2017. Published by Elsevier Ltd.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26589524','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26589524"><span>Expected and Unexpected Consequences of the Affordable Care Act: The Impact on Patients and Surgeons-Pro and <span class="hlt">Con</span> Arguments.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Rudnicki, Marek; Armstrong, John H; Clark, Clancy; Marcus, Stuart G; Sacks, Lee; Moser, A James; Reid-Lombardo, K Marie</p> <p>2016-02-01</p> <p>The Patient Protection and Affordable Care Act (PPACA), called the Affordable Care Act (ACA) or "ObamaCare" for short, was enacted in 2010. The Public Policy and Advocacy Committee of the Society for Surgery of the Alimentary Tract (SSAT) hosted a debate with an expert panel to discuss the ACA and its impact on surgical care after the first year of patient enrollment. The purpose of this debate was to focus on the impact of ACA on the public and surgeons. At the core of the ACA are insurance industry reforms and expanded coverage, with a goal of improved clinical outcomes and reduced costs of care. We have observed supportive and opposing views on ACA. Nonetheless, we will witness major shifts in health care delivery as well as restructuring of our relationship with payers, institutions, and patients. With the rapidly changing health care landscape, surgeons will become key members of health systems and will likely need to lead transition from solo-practice to integrated care systems. The full effects of the ACA remain unrealized, but its implementation has begun to change the map of the American health care system and will surely impact the practice of surgery. Herein, we provide a synopsis of the "pro" and "<span class="hlt">con</span>" arguments for the expected and unexpected consequences of the ACA on society and surgeons.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28673559','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28673559"><span><span class="hlt">CON</span>4EI: Bovine Corneal Opacity and Permeability (BCOP) test for hazard identification and labelling of eye irritating chemicals.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Verstraelen, Sandra; Maglennon, Gareth; Hollanders, Karen; Boonen, Francis; Adriaens, Els; Alépée, Nathalie; Drzewiecka, Agnieszka; Gruszka, Katarzyna; Kandarova, Helena; Willoughby, Jamin A; Guest, Robert; Schofield, Jane; Van Rompay, An R</p> <p>2017-10-01</p> <p>Assessment of ocular irritation potential is an international regulatory requirement in the safety evaluation of industrial and consumer products. None in vitro ocular irritation assays are capable of fully categorizing chemicals as stand-alone. Therefore, the CEFIC-LRI-AIMT6-VITO <span class="hlt">CON</span>4EI consortium assessed the reliability of eight in vitro test methods and computational models as well as established a tiered-testing strategy. One of the selected assays was Bovine Corneal Opacity and Permeability (BCOP). In this project, the same corneas were used for measurement of opacity using the OP-KIT, the Laser Light-Based Opacitometer (LLBO) and for histopathological analysis. The results show that the accuracy of the BCOP OP-KIT in identifying Cat 1 chemicals was 73.8% while the accuracy was 86.3% for No Cat chemicals. BCOP OP-KIT false negative results were often related to an in vivo classification driven by conjunctival effects only. For the BCOP LLBO, the accuracy in identifying Cat 1 chemicals was 74.4% versus 88.8% for No Cat chemicals. The BCOP LLBO seems very promising for the identification of No Cat liquids but less so for the identification of solids. Histopathology as an additional endpoint to the BCOP test method does not reduce the false negative rate substantially for in vivo Cat 1 chemicals. Copyright © 2017 Elsevier Ltd. All rights reserved.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/20180002425','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/20180002425"><span>Airspace Technology Demonstration 2 (ATD-2) Phase 1 Concept of Use (<span class="hlt">Con</span>Use)</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Jung, Yoon; Engelland, Shawn; Capps, Richard; Coppenbarger, Rich; Hooey, Becky; Sharma, Shivanjli; Stevens, Lindsay; Verma, Savita; Lohr, Gary; Chevalley, Eric; <a style="text-decoration: none; " href="javascript:void(0); " onClick="displayelement('author_20180002425'); toggleEditAbsImage('author_20180002425_show'); toggleEditAbsImage('author_20180002425_hide'); "> <img style="display:inline; width:12px; height:12px; " src="images/arrow-up.gif" width="12" height="12" border="0" alt="hide" id="author_20180002425_show"> <img style="width:12px; height:12px; display:none; " src="images/arrow-down.gif" width="12" height="12" border="0" alt="hide" id="author_20180002425_hide"></p> <p>2018-01-01</p> <p>This document presents an operational Concept of Use (<span class="hlt">Con</span>Use) for the Phase 1 Baseline Integrated Arrival, Departure, and Surface (IADS) prototype system of NASA's Airspace Technology Demonstration 2 (ATD-2) sub-project, which began demonstration in 2017 at Charlotte Douglas International Airport (CLT). NASA is developing the IADS system under the ATD-2 sub-project in coordination with the Federal Aviation Administration (FAA) and aviation industry partners. The primary goal of ATD-2 sub-project is to improve the predictability and the operational efficiency of the air traffic system in metroplex environments, through the enhancement, development, and integration of the nation's most advanced and sophisticated arrival, departure, and surface prediction, scheduling, and management systems. The ATD-2 effort is a five-year research activity through 2020. The initial phase of the ATD-2 sub-project, which is the focus of this document, will demonstrate the Phase 1 Baseline IADS capability at CLT in 2017. The Phase 1 Baseline IADS capabilities of the ATD-2 sub-project consists of: (a) Strategic and tactical surface scheduling to improve efficiency and predictability of airport surface operations, (b) Tactical departure scheduling to enhance merging of departures into overhead traffic streams via accurate predictions of takeoff times and automated coordination between the Airport Traffic Control Tower (ATCT, or Tower) and the Air Route Traffic Control Center (ARTCC, or Center), (c) Improvements in departure surface demand predictions in Time Based Flow Management (TBFM), (d) A prototype Electronic Flight Data (EFD) system provided by the FAA via the Terminal Flight Data Manager (TFDM) early implementation effort, and (e) Improved situational awareness and demand predictions through integration with the Traffic Flow Management System (TFMS), TBFM, and TFDM (3Ts) for electronic data integration and exchange, and an on-screen dashboard displaying pertinent analytics in real</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014GGG....15.3322H','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014GGG....15.3322H"><span>Long-term (17 Ma) turbidite record of the timing and frequency of large flank collapses of the Canary Islands</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Hunt, J. E.; Talling, P. J.; Clare, M. A.; Jarvis, I.; Wynn, R. B.</p> <p>2014-08-01</p> <p>Volcaniclastic turbidites on the Madeira Abyssal Plain provide a record of large-volume volcanic island flank collapses from the Canary Islands. This long-term record spans 17 Ma, and comprises 125 volcaniclastic beds. Determining the timing, provenance and volumes of these turbidites provides key information about the occurrence of mass wasting from the Canary Islands, especially the western islands of Tenerife, La Palma and El <span class="hlt">Hierro</span>. These turbidite records demonstrate that landslides often coincide with protracted periods of volcanic edifice growth, suggesting that loading of the volcanic edifices may be a key preconditioning factor for landslide triggers. Furthermore, the last large-volume failures from Tenerife coincide with explosive volcanism at the end of eruptive cycles. Many large-volume Canary Island landslides also occurred during periods of warmer and wetter climates associated with sea-level rise and subsequent highstand. However, these turbidites are not serially dependent and any association with climate or sea level change is not statistically significant.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2018JVGR..356..127C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2018JVGR..356..127C"><span>Serreta 1998-2001 submarine volcanic eruption, offshore Terceira (Azores): Characterization of the vent and inferences about the eruptive dynamics</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Casas, David; Pimentel, Adriano; Pacheco, José; Martorelli, Eleonora; Sposato, Andrea; Ercilla, Gemma; Alonso, Belen; Chiocci, Francesco</p> <p>2018-05-01</p> <p>High-resolution bathymetric data and seafloor sampling were used to characterize the most recent volcanic eruption in the Azores region, the 1998-2001 Serreta submarine eruption. The vent of the eruption is proposed to be an asymmetric topographic high, composed of two coalescing volcanic cones, underlying the location where lava balloons had been observed at the sea surface during the eruption. The volcanic products related to the 1998-2001 eruption are constrained to an area of 0.5 km2 around the proposed vent position. A submarine Strombolian-style eruption producing basaltic lava balloons, ash and coarse scoriaceous materials with limited lateral dispersion led to the buildup of the cones. The 1998-2001 Serreta eruption shares many similarities with other intermediate-depth lava balloon-forming eruptions (e.g., the 1891 eruption offshore Pantelleria and the 2011-2012 eruption south of El <span class="hlt">Hierro</span>), revealing the particular conditions needed for the production of this unusual and scarcely documented volcanic product.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/16351960','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/16351960"><span>Relationship between diet and helminths in Gallotia caesaris (Sauria: Lacertidae).</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Martin, J E; Llorente, G A; Roca, V; Carretero, M A; Montori, A; Santos, X; Romeu, R</p> <p>2005-01-01</p> <p>Diet and helminth fauna were analysed in Gallotia caesaris, a small lacertid lizard endemic to El <span class="hlt">Hierro</span> (Canary Islands, Spain) in order to study the evolutionary and functional relationships between the two traits. This species is omnivorous but consumed a high proportion (82.13%) of plant matter including not only seeds but also leaves and other vegetative parts. Helminth fauna included many helminth species typical of herbivorous reptiles. Both herbivory and helminth presence were higher than expected for a lizard of its size. Comparison with other lacertids suggests that both traits result from an adaptation to insular conditions but that some "evolutionary time" to develop them is needed. Canarian Gallotia lizards, a separate lineage evolving for a long time in insularity, constitutes the most advanced lacertid group in this way. Nevertheless, results for G. caesaris indicate that helminth fauna also changes seasonally tracking variation in diet (and herbivory) throughout the year, which suggests a dynamic interaction between diet and helminth parasites.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015EGUGA..17.5101R','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015EGUGA..17.5101R"><span>High volcanic seismic b-values: Real or artefacts?</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Roberts, Nick; Bell, Andrew; Main, Ian G.</p> <p>2015-04-01</p> <p>The b-value of the Gutenberg-Richter distribution quantifies the relative proportion of large to small magnitude earthquakes in a catalogue, in turn related to the population of fault rupture areas and the average slip or stress drop. Accordingly the b-value is an important parameter to consider when evaluating seismic catalogues as it has the potential to provide insight into the temporal or spatial evolution of the system, such as fracture development or changes in the local stress regime. The b-value for tectonic seismicity is commonly found to be close to 1, whereas much higher b-values are frequently reported for volcanic and induced seismicity. Understanding these differences is important for understanding the processes controlling earthquake occurrence in different settings. However, it is possible that anomalously high b-values could arise from small sample sizes, under-estimated completeness magnitudes, or other poorly applied methodologies. Therefore, it is important to establish a rigorous workflow for analyzing these datasets. Here we examine the frequency-magnitude distributions of volcanic earthquake catalogues in order to determine the significance of apparently high b-values. We first derive a workflow for computing the completeness magnitude of a seismic catalogue, using synthetic catalogues of varying shape, size, and known b-value. We find the best approach involves a combination of three methods: 'Maximum Curvature', 'b-value stability', and the 'Goodness-of-Fit test'. To calculate a reliable b-value with an error ≤0.25, the maximum curvature method is preferred for a 'sharp-peaked' discrete distribution. For a catalogue with a broader peak the b-value stability method is the most reliable with the Goodness-of-Fit test being an acceptable backup if the b-value stability method fails. We apply this workflow to earthquake catalogues from El <span class="hlt">Hierro</span> (2011-2013) and Mt Etna (1999-2013) volcanoes. In general, we find the b-value to be equal to or</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://eric.ed.gov/?q=Frustration+AND+education+AND+middle+AND+school+AND+students&pg=4&id=EJ548882','ERIC'); return false;" href="https://eric.ed.gov/?q=Frustration+AND+education+AND+middle+AND+school+AND+students&pg=4&id=EJ548882"><span>Aprendiendo <span class="hlt">con</span> Veronica.</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>McDonald-O'Brien, Pat</p> <p>1996-01-01</p> <p>Describes how an elementary school literacy specialist worked with and saw the dilemmas, frustrations, and heartaches of a new student from Puerto Rico. Notes that the literacy specialist learned valuable lessons and gained an appreciation for the need to honor and celebrate, engage and instruct all students from all over the globe. (SR)</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://files.eric.ed.gov/fulltext/EJ1017994.pdf','ERIC'); return false;" href="http://files.eric.ed.gov/fulltext/EJ1017994.pdf"><span>Neo-<span class="hlt">Conned</span> University</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Jones, Andee</p> <p>2014-01-01</p> <p>Censorship, says Australian political theorist John Keane (1991), can "echo within us, take up residence within ourselves, spying on us, a private amanuensis who reminds us never to go too far... It makes us zip our lips, tremble and think twice" (p. 39). It can also make us sick. The author states that this is her argument here: that,…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://espanol.epa.gov/espanol/conozcanos','PESTICIDES'); return false;" href="https://espanol.epa.gov/espanol/conozcanos"><span><span class="hlt">Con</span>ózcanos</span></a></p> <p><a target="_blank" href="http://www.epa.gov/pesticides/search.htm">EPA Pesticide Factsheets</a></p> <p></p> <p></p> <p>Principal de la EPA: información sobre el Administrador o la Administradora, los altos directivos; ubicaciones y direcciones de las oficinas; presupuesto, la planificación y los resultados de rendimiento</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2012AGUFM.H12D..03N','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2012AGUFM.H12D..03N"><span>Emerging and Legacy Contaminants in The Foodweb in The Lower Columbia River: USGS <span class="hlt">Con</span>Hab Project</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Nilsen, E. B.; Alvarez, D.; Counihan, T.; Elias, E.; Gelfenbaum, G. R.; Hardiman, J.; Jenkins, J.; Mesa, M.; Morace, J.; Patino, R.; Torres, L.; Waite, I.; Zaugg, S.</p> <p>2012-12-01</p> <p>An interdisciplinary study, USGS Columbia River Contaminants and Habitat Characterization (<span class="hlt">Con</span>Hab) project, investigates transport pathways, chemical fate, and effects of polybrominated diphenyl ethers (PBDEs) and other endocrine disrupting chemicals (EDCs) in aquatic media and the foodweb in the lower Columbia River, Oregon and Washington. Polar organic chemical integrative samplers (POCIS) and semipermeable membrane devices (SPMDs) were co-deployed at each of 10 sites in 2008 to provide a measure of the dissolved concentrations of select PBDEs, chlorinated pesticides, and other EDCs. PBDE-47 was the most prevalent of the PBDEs detected. Numerous organochlorine pesticides, both banned and current-use, including hexachlorobenzene, pentachloroanisole, dichlorodiphenyltrichloroethane (DDT) and its degradates, chlorpyrifos, endosulfan, and the endosulfan degradation products, were measured at each site. EDCs commonly detected included a series of polycyclic aromatic hydrocarbons (PAHs), fragrances (galaxolide), pesticides (chlorpyrifos and atrazine), plasticizers (phthalates), and flame retardants (phosphates). The downstream sites tended to have the highest concentrations of contaminants in the lower Columbia River. In 2009 and 2010 passive samplers were deployed and resident largescale suckers (Catostomus macrocheilus) and surface bed sediments were collected at three of the original sites representing a gradient of exposure based on 2008 results. Brain, fillet, liver, stomach, and gonad tissues were analyzed. Chemical concentrations were highest in livers, followed by brain, stomach, gonad, and, lastly, fillet. Concentrations of halogenated compounds in tissue samples ranged from <1 to 400 ng g-1 wet tissue. PBDEs, organochlorine pesticides, DDT and its degradates, and polychlorinated biphenyls (PCBs) were detected at all sites in nearly all organs tested. PBDE congeners most frequently detected and at the highest concentrations were PBDE-47 > PBDE-100 > PBDE-154</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/12069280','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/12069280"><span>Pros, <span class="hlt">cons</span>, and current indications of open craniotomy versus gamma knife in the treatment of arteriovenous malformations and the role of endovascular embolization.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Surdell, Daniel L; Bhattacharjee, Sumon; Loftus, Christopher M</p> <p>2002-06-01</p> <p>The successful treatment of an intracranial arteriovenous malformation poses both technical and conceptual problems to the neurosurgeon. Treatment decisions are made in light of current understanding of the natural history of these lesions. It is important to understand the pros, <span class="hlt">cons</span> and current indication of open craniotomy vs. gamma knife in the treatment of arteriovenous malformations and the role of endovascular embolization. Surgical removal of an arteriovenous malformation is indicated when the operative risk is less than the morbidity and mortality associated with its natural history. The treatment goal of complete angiographic obliteration of arteriovenous malformations is achieved most effectively by microneurosurgery in low-grade lesions. Large lesions frequently require a combination of embolization and microsurgery. Although recent advances in technology and medical management have allowed previously inoperable arteriovenous malformations to be surgically excised, there is still a small group of arteriovenous malformations that cannot be excised safely due to their size and location. Stereotactic radiosurgery is clearly an important adjunct in the multimodality treatment approach for large arteriovenous malformations. Endovascular embolization can potentially increase safety and efficacy in the treatment of arteriovenous malformations when applied to selective cases with well-defined treatment goals.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28801046','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28801046"><span><span class="hlt">CON</span>4EI: Short Time Exposure (STE) test method for hazard identification and labelling of eye irritating chemicals.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Adriaens, E; Willoughby, J A; Meyer, B R; Blakeman, L C; Alépée, N; Fochtman, P; Guest, R; Kandarova, H; Verstraelen, S; Van Rompay, A R</p> <p>2018-06-01</p> <p>Assessment of ocular irritancy is an international regulatory requirement in the safety evaluation of industrial and consumer products. Although many in vitro ocular irritation assays exist, alone they are incapable of fully categorizing chemicals. Therefore, the CEFIC-LRI-AIMT6-VITO <span class="hlt">CON</span>4EI consortium was developed to assess the reliability of eight in vitro test methods and establish an optimal tiered-testing strategy. One assay selected was the Short Time Exposure (STE) assay. This assay measures the viability of SIRC rabbit corneal cells after 5min exposure to 5% and 0.05% solutions of test material, and is capable of categorizing of Category 1 and No Category chemicals. The accuracy of the STE test method to identify Cat 1 chemicals was 61.3% with 23.7% sensitivity and 95.2% specificity. If non-soluble chemicals and unqualified results were excluded, the performance to identify Cat 1 chemicals remained similar (accuracy 62.2% with 22.7% sensitivity and 100% specificity). The accuracy of the STE test method to identify No Cat chemicals was 72.5% with 66.2% sensitivity and 100% specificity. Excluding highly volatile chemicals, non-surfactant solids and non-qualified results resulted in an important improvement of the performance of the STE test method (accuracy 96.2% with 81.8% sensitivity and 100% specificity). Furthermore, it seems that solids are more difficult to test in the STE, 71.4% of the solids resulted in unqualified results (solubility issues and/or high variation between independent runs) whereas for liquids 13.2% of the results were not qualified, supporting the restriction of the test method regarding the testing of solids. Copyright © 2017. Published by Elsevier Ltd.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li class="active"><span>24</span></li> <li><a href="#" onclick='return showDiv("page_25");'>25</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_24 --> <div id="page_25" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li class="active"><span>25</span></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="481"> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/20029660','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/20029660"><span>Antiviral usage for H1N1 treatment: pros, <span class="hlt">cons</span> and an argument for broader prescribing guidelines in the United States.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Goldstein, Edward; Lipsitch, Marc</p> <p>2009-10-29</p> <p>Current CDC guidelines for antiviral treatment of people with influenza like illness (ILI) effectively discourage treatment of people with no underlying medical conditions unless they exhibit severe symptoms, such as evidence of lower respiratory tract infection or clinical deterioration. This guidance is unlike that provided by some other countries, which allow for treatment of most moderately symptomatic individuals. We examine evidence for benefits of antiviral usage for influenza treatment, including its relation to severe outcomes for the current pandemic H1N1 strain. We also discuss some of the potential <span class="hlt">cons</span> of antiviral usage. In the current situation in the US, with an elevated and evidently growing burden of influenza hospitalizations and mortality, a high percentage of individuals infected with influenza (with almost all of those carrying the H1N1pdm strain) among those who exhibit ILI and get tested for influenza virus, very low levels of antiviral resistance and little time left for antiviral resistance to take off before large quantities of vaccine become available, we think it is worthwhile to consider a revision to the current antiviral usage recommendations, such that physicians would be encouraged to consider prescribing antivirals to individuals with moderate to severe symptoms who present for treatment.Note: Very recently CDC has adopted clarifications for its antiviral usage guidelines: http://www.cdc.gov/H1N1flu/antivirals/facts_clinicians.htm.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29598995','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29598995"><span>Reprint of "<span class="hlt">CON</span>4EI: Bovine Corneal Opacity and Permeability (BCOP) test for hazard identification and labelling of eye irritating chemicals".</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Verstraelen, Sandra; Maglennon, Gareth; Hollanders, Karen; Boonen, Francis; Adriaens, Els; Alépée, Nathalie; Drzewiecka, Agnieszka; Gruszka, Katarzyna; Kandarova, Helena; Willoughby, Jamin A; Guest, Robert; Schofield, Jane; Van Rompay, An R</p> <p>2018-06-01</p> <p>Assessment of ocular irritation potential is an international regulatory requirement in the safety evaluation of industrial and consumer products. None in vitro ocular irritation assays are capable of fully categorizing chemicals as stand-alone. Therefore, the CEFIC-LRI-AIMT6-VITO <span class="hlt">CON</span>4EI consortium assessed the reliability of eight in vitro test methods and computational models as well as established a tiered-testing strategy. One of the selected assays was Bovine Corneal Opacity and Permeability (BCOP). In this project, the same corneas were used for measurement of opacity using the OP-KIT, the Laser Light-Based Opacitometer (LLBO) and for histopathological analysis. The results show that the accuracy of the BCOP OP-KIT in identifying Cat 1 chemicals was 73.8% while the accuracy was 86.3% for No Cat chemicals. BCOP OP-KIT false negative results were often related to an in vivo classification driven by conjunctival effects only. For the BCOP LLBO, the accuracy in identifying Cat 1 chemicals was 74.4% versus 88.8% for No Cat chemicals. The BCOP LLBO seems very promising for the identification of No Cat liquids but less so for the identification of solids. Histopathology as an additional endpoint to the BCOP test method does not reduce the false negative rate substantially for in vivo Cat 1 chemicals. Copyright © 2017 Elsevier Ltd. All rights reserved.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/6809820','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/6809820"><span>The role of Ia molecules in the activation of T lymphocytes. I. The activation of an IL 1-dependent IL 2-producing T cell hybridoma by <span class="hlt">Con</span> A requires an interaction, which is not H-2-restricted, with an Ia-bearing accessory cell.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Rock, K L</p> <p>1982-10-01</p> <p>A model of accessory cell-dependent lectin-mediated T cell activation was investigated by utilizing a mitogen-inducible T cell hybridoma. A continuous MHC-restricted antigen-specific T cell line was fused with the azaguanine-resistant AKR thymoma BW5147. A hybrid, RF1.16B, was identified that is minimally inducible by <span class="hlt">Con</span> A stimulation alone but is stimulated by <span class="hlt">Con</span> A in the presence of T cell-depleted accessory cells to produce interleukin 2. The accessory cell function can be replaced by the monokine interleukin 1. Thus the lectin is a sufficient trigger for the hybrid in the absence of MHC restriction elements. The accessory cell function from splenocytes is provided by a non-B, non-T, predominantly Ia-bearing radioresistant cell. The interaction between the RF1.16B hybrid and the accessory cell population is not H-2-restricted. Control experiments, including the use of a cloned source of accessory cells, ruled out contaminating T cells or direct lectin effects as an explanation for the lack of H-2 restriction. The finding that an Ia-bearing cell is required for activation in an MHC-nonrestricted manner is discussed, and a hypothesis is raised that Ia antigens may play a role in addition to that of being a restriction element.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3683517','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3683517"><span>Implantation des sites de soins communautaires en République Démocratique du Congo: <span class="hlt">cons</span>écration d'un double standard dans l'accès aux soins</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Dunia, Gisèle Mawazo Binti</p> <p>2013-01-01</p> <p>Depuis 2005, la République Démocratique du Congo a amorcé l'implantation des sites de soins communautaires. Cette stratégie a pour objectif de rapprocher les services de santé des populations éloignées. Bien que cela parte d'une bonne intention, elle résulte, à notre sens, en une <span class="hlt">cons</span>écration d'un système de santé à deux vitesses. En effet, les populations vivant en ville ont accès à des soins prestés par des agents de santé formés alors que celles vivant en milieu rural reculé ont pour prestataires de soins des relais communautaires. Cette situation marginalise encore plus des populations dont la situation géographique est déjà préoccupante. Pourtant, la population est prête à parcourir des kilomètres en échange d'un service qu'elle estime de qualité. PMID:23785563</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25127880','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25127880"><span>An inevitable wave of prescription drug monitoring programs in the context of prescription opioids: pros, <span class="hlt">cons</span> and tensions.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Islam, M Mofizul; McRae, Ian S</p> <p>2014-08-16</p> <p>In an effort to control non-medical use and/or medical abuse of prescription drugs, particularly prescription opioids, electronic prescription drug monitoring programs (PDMP) have been introduced in North-American countries, Australia and some parts of Europe. Paradoxically, there are simultaneous pressures to increase opioid prescribing for the benefit of individual patients and to reduce it for the sake of public health, and this pressure warrants a delicate balance of appropriate therapeutic uses of these drugs with the risk of developing dependence. This article discusses pros and <span class="hlt">cons</span> of PDMP in reducing diversion of prescription opioids, without hampering access to those medications for those with genuine needs, and highlights tensions around PDMP implementation. PDMPs may help alleviate diversion, over-prescription and fraudulent prescribing/dispensing; prompt drug treatment referrals; avoid awkward drug urine test; and inform spatial changes in prescribing practices and help designing tailored interventions. Fear of legal retribution, privacy and data security, potential confusion about addiction and pseudo-addiction, and potential undue pressure of detecting misuse/diversion - are the major problems. There are tensions about unintended consequence of excessive regulatory enforcements, corresponding collateral damages particularly about inadequate prescribing for patients with genuine needs, and mandatory consultation requirements of PDMP. In this era of information technology PDMP is likely to flourish and remain with us for a long time. A clear standard of practice against which physicians' care will be judged may expedite the utilisation of PDMP. In addition, adequate training on addiction and pain management along with public awareness, point-of-supply data entry from pharmacy, point-of-care real-time access to data, increasing access to addiction treatment and appropriate regulatory enforcement preferably through healthcare administration, together</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4138942','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4138942"><span>An inevitable wave of prescription drug monitoring programs in the context of prescription opioids: pros, <span class="hlt">cons</span> and tensions</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p></p> <p>2014-01-01</p> <p>Background In an effort to control non-medical use and/or medical abuse of prescription drugs, particularly prescription opioids, electronic prescription drug monitoring programs (PDMP) have been introduced in North-American countries, Australia and some parts of Europe. Paradoxically, there are simultaneous pressures to increase opioid prescribing for the benefit of individual patients and to reduce it for the sake of public health, and this pressure warrants a delicate balance of appropriate therapeutic uses of these drugs with the risk of developing dependence. This article discusses pros and <span class="hlt">cons</span> of PDMP in reducing diversion of prescription opioids, without hampering access to those medications for those with genuine needs, and highlights tensions around PDMP implementation. Discussion PDMPs may help alleviate diversion, over-prescription and fraudulent prescribing/dispensing; prompt drug treatment referrals; avoid awkward drug urine test; and inform spatial changes in prescribing practices and help designing tailored interventions. Fear of legal retribution, privacy and data security, potential confusion about addiction and pseudo-addiction, and potential undue pressure of detecting misuse/diversion - are the major problems. There are tensions about unintended consequence of excessive regulatory enforcements, corresponding collateral damages particularly about inadequate prescribing for patients with genuine needs, and mandatory consultation requirements of PDMP. Summary In this era of information technology PDMP is likely to flourish and remain with us for a long time. A clear standard of practice against which physicians’ care will be judged may expedite the utilisation of PDMP. In addition, adequate training on addiction and pain management along with public awareness, point-of-supply data entry from pharmacy, point-of-care real-time access to data, increasing access to addiction treatment and appropriate regulatory enforcement preferably through</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26896109','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26896109"><span>Vivir <span class="hlt">Con</span> Un Corazón Saludable: a Community-Based Educational Program Aimed at Increasing Cardiovascular Health Knowledge in High-Risk Hispanic Women.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Romero, Daniela C; Sauris, Aileen; Rodriguez, Fátima; Delgado, Daniela; Reddy, Ankita; Foody, JoAnne M</p> <p>2016-03-01</p> <p>Hispanic women suffer from high rates of cardiometabolic risk factors and an increasingly disproportionate burden of cardiovascular disease (CVD). Particularly, Hispanic women with limited English proficiency suffer from low levels of CVD knowledge associated with adverse CVD health outcomes. Thirty-two predominantly Spanish-speaking Hispanic women completed, Vivir <span class="hlt">Con</span> un Corazón Saludable (VCUCS), a culturally tailored Spanish language-based 6-week intensive community program targeting CVD health knowledge through weekly interactive health sessions. A 30-question CVD knowledge questionnaire was used to assess mean changes in CVD knowledge at baseline and postintervention across five major knowledge domains including CVD epidemiology, dietary knowledge, medical information, risk factors, and heart attack symptoms. Completion of the program was associated with a statistically significant (p < 0.001) increase in total mean CVD knowledge scores from 39 % (mean 11.7/30.0) to 66 % (mean 19.8/30.0) postintervention consistent with a 68 % increase in overall mean CVD scores. There was a statistically significant (p < 0.001) increase in mean knowledge scores across all five CVD domains. A culturally tailored Spanish language-based health program is effective in increasing CVD awareness among high CVD risk Hispanic women with low English proficiency and low baseline CVD knowledge.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24787471','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24787471"><span>Extravirgin olive oil consumption reduces risk of atrial fibrillation: the PREDIMED (Prevención <span class="hlt">con</span> Dieta Mediterránea) trial.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Martínez-González, Miguel Á; Toledo, Estefanía; Arós, Fernando; Fiol, Miquel; Corella, Dolores; Salas-Salvadó, Jordi; Ros, Emilio; Covas, Maria I; Fernández-Crehuet, Joaquín; Lapetra, José; Muñoz, Miguel A; Fitó, Monserrat; Serra-Majem, Luis; Pintó, Xavier; Lamuela-Raventós, Rosa M; Sorlí, Jose V; Babio, Nancy; Buil-Cosiales, Pilar; Ruiz-Gutierrez, Valentina; Estruch, Ramón; Alonso, Alvaro</p> <p>2014-07-01</p> <p>The PREDIMED (Prevención <span class="hlt">con</span> Dieta Mediterránea) randomized primary prevention trial showed that a Mediterranean diet enriched with either extravirgin olive oil or mixed nuts reduces the incidence of stroke, myocardial infarction, and cardiovascular mortality. We assessed the effect of these diets on the incidence of atrial fibrillation in the PREDIMED trial. Participants were randomly assigned to 1 of 3 diets: Mediterranean diet supplemented with extravirgin olive oil, Mediterranean diet supplemented with mixed nuts, or advice to follow a low-fat diet (control group). Incident atrial fibrillation was adjudicated during follow-up by an events committee blinded to dietary group allocation. Among 6705 participants without prevalent atrial fibrillation at randomization, we observed 72 new cases of atrial fibrillation in the Mediterranean diet with extravirgin olive oil group, 82 in the Mediterranean diet with mixed nuts group, and 92 in the control group after median follow-up of 4.7 years. The Mediterranean diet with extravirgin olive oil significantly reduced the risk of atrial fibrillation (hazard ratio, 0.62; 95% confidence interval, 0.45-0.85 compared with the control group). No effect was found for the Mediterranean diet with nuts (hazard ratio, 0.89; 95% confidence interval, 0.65-1.20). In the absence of proven interventions for the primary prevention of atrial fibrillation, this post hoc analysis of the PREDIMED trial suggests that extravirgin olive oil in the context of a Mediterranean dietary pattern may reduce the risk of atrial fibrillation. http://www.controlled-trials.com. Unique identifier: ISRCTN35739639. © 2014 American Heart Association, Inc.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014EGUGA..1614644G','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014EGUGA..1614644G"><span>A methodological approach to comparing pros and <span class="hlt">cons</span> of delocalizing villages: socio-economic and technical issues</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Guadagno, Eleonora; Iovine, Giulio G. R.; Petrucci, Olga; Forciniti, Pinuccia R.</p> <p>2014-05-01</p> <p> Cavallerizzo have been analysed within the frame of a PhD thesis by one of the authors. The present study focuses on the Cavallerizzo case study to discuss a methodological approach useful to comparing pros and <span class="hlt">cons</span> of delocalizing villages, aiming at properly considering socio-economic effects in addition to technical issues.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2003cnam.conf...84B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2003cnam.conf...84B"><span>Estudio de la fotoabsorción y fotoionización de la molécula de alta relevancia atmosférica no a través de los estados Rydberg <span class="hlt">con</span> la metodología MQDO</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Bustos, E.; Velasco, A. M.; Martín, I.; Lavín, C.</p> <p></p> <p>Los procesos de fotoionización son de una importancia fundamental [1] y encuentran aplicación en un gran número de contextos científicos: Astrofísica [2], química de las radiaciones, biología. Los investigadores de dichos campos, necesitan de valores de fiables de secciones eficaces para la fotoionización parcial, la Fotoabsorción, así como para los procesos de fotofragmentación en amplios intervalos espectrales, particularmente en estudios de modelización [3-5]. En este trabajo se ha centrado la atención sobre el oxido nítrico, que se ha considerado apropiado y relevante por varios motivos: por el trascendental papel que representa en la física y química de la alta atmosfera [6], aparte de por estar íntimamente relacionado <span class="hlt">con</span> los problemas de contaminación. Los procesos de recombinación disociativa [7] del NO, donde los estados Rydberg se encuentran directamente implicados, son relevantes, por ejemplo, en las regiones E y F de la ionosfera [7]. En este trabajo se estudia la fotoionización del NO desde el estado fundamental <span class="hlt">con</span> la versión molecular del método del orbital de defecto cuántico (MQDO). Para ello se calcula el diferencial de las fuerzas de oscilador parciales que constituyen los canales de fotoionización del NO desde el estado fundamental. La continuidad del diferencial de fuerza de oscilador calculada a través del umbral de fotoionización, esto es, en las regiones del espectro discreta y del continua, se adopta como criterio de calidad la escasez de datos comparativos [8].</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28882315','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28882315"><span>Is atherosclerosis imaging the most sensitive way to assess patients' risk and the best way to conduct future drug trials? A pros-and-<span class="hlt">cons</span> debate.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Nanchen, David; Raggi, Paolo</p> <p>2017-11-01</p> <p>Atherosclerosis imaging has been the focus of intense debate and research for several decades. Among its primary applications are risk stratification of asymptomatic individuals and follow-up of atherosclerosis progression under a variety of treatments designed to retard or regress the development of arterial disease. Although endorsed and supported by many, this approach has been fiercely opposed by several key opinion leaders over the years. Similarly, regulatory agencies have raised a number of objections to resist the approval of new drugs and devices based on surrogate imaging markers. However, there is a large body of evidence in the medical literature that shows that risk stratification is improved with implementation of atherosclerosis imaging. Additionally, numerous lipid-modifying agents have been tested as far as their ability to affect progression of atherosclerosis, and in many cases the information obtained with imaging was in line with the outcome of subsequent clinical trials. This pros-and-<span class="hlt">cons</span> debate was staged to bring up in a fun and provoking way the main arguments in favour or against the application of atherosclerosis imaging in the main settings described above. Copyright © 2017 Elsevier B.V. All rights reserved.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25475289','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25475289"><span>Coagulase-negative staphylococci (<span class="hlt">CoNS</span>) isolated from ready-to-eat food of animal origin--phenotypic and genotypic antibiotic resistance.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Chajęcka-Wierzchowska, Wioleta; Zadernowska, Anna; Nalepa, Beata; Sierpińska, Magda; Łaniewska-Trokenheim, Łucja</p> <p>2015-04-01</p> <p>The aim of this work was to study the pheno- and genotypical antimicrobial resistance profile of coagulase negative staphylococci (<span class="hlt">CoNS</span>) isolated from 146 ready-to-eat food of animal origin (cheeses, cured meats, sausages, smoked fishes). 58 strains were isolated, they were classified as Staphylococcus xylosus (n = 29), Staphylococcus epidermidis (n = 16); Staphylococcus lentus (n = 7); Staphylococcus saprophyticus (n = 4); Staphylococcus hyicus (n = 1) and Staphylococcus simulans (n = 1) by phenotypic and genotypic methods. Isolates were tested for resistance to erythromycin, clindamycin, gentamicin, cefoxitin, norfloxacin, ciprofloxacin, tetracycline, tigecycline, rifampicin, nitrofurantoin, linezolid, trimetoprim, sulphamethoxazole/trimethoprim, chloramphenicol, quinupristin/dalfopristin by the disk diffusion method. PCR was used for the detection of antibiotic resistance genes encoding: methicillin resistance--mecA; macrolide resistance--erm(A), erm(B), erm(C), mrs(A/B); efflux proteins tet(K) and tet(L) and ribosomal protection proteins tet(M). For all the tet(M)-positive isolates the presence of conjugative transposons of the Tn916-Tn1545 family was determined. Most of the isolates were resistant to cefoxitin (41.3%) followed by clindamycin (36.2%), tigecycline (24.1%), rifampicin (17.2%) and erythromycin (13.8%). 32.2% staphylococcal isolates were multidrug resistant (MDR). All methicillin resistant staphylococci harboured mecA gene. Isolates, phenotypic resistant to tetracycline, harboured at least one tetracycline resistance determinant on which tet(M) was most frequent. All of the isolates positive for tet(M) genes were positive for the Tn916-Tn1545 -like integrase family gene. In the erythromycin-resistant isolates, the macrolide resistance genes erm(C) or msr(A/B) were present. Although coagulase-negative staphylococci are not classical food poisoning bacteria, its presence in food could be of public health significance due to the possible spread of</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2003JAP....93.8412L','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2003JAP....93.8412L"><span>Biquadratic coupling through nano-oxide layers in pinned layers of IrMn-based spin valves</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Lai, Chih-Huang; Lu, K. H.</p> <p>2003-05-01</p> <p>We have investigated the coupling between top and bottom pinned layers through various nano-oxide layers (NOLs) in IrMn-based spin valves. The NOLs were formed by using oxygen-plasma oxidation or natural oxidation on 1 nm metallic layers. By inserting naturally oxidized Co-NOLs in the pinned layer, strong ferromagnetic coupling through NOLs and high specularity at the NOL interface were achieved. In contrast, when the plasma-oxidized Co-NOLs were inserted, ferromagnetic coupling through NOLs disappeared, plausibly due to the formation of nonferromagnetic oxides, which led to a low magnetoresistance (MR). Insertion of naturally oxidized Ni80Fe20-NOLs showed the same results as that of naturally oxidized Co-NOLs. On the other hand, biquadratic coupling between top and bottom pinned-Co90Fe10 layers was observed by inserting plasma-oxidized Ni80Fe20-NOLs. The highest MR was obtained when the field was applied along the direction perpendicular to the field-annealing direction. Similar biquadratic coupling was also found with naturally oxidized or plasma-oxidized <span class="hlt">Fe-NOLs</span>. We suggest that the biquadratic coupling between pinned Co90Fe10 layers through NOLs results from the coupling between Fe (or Co90Fe10) and Fe+3 oxides</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29567150','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29567150"><span>Application of CE-ICP-MS and CE-ESI-MS/MS for identification of Zn-binding ligands in Goji berries extracts.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Ruzik, Lena; Kwiatkowski, Piotr</p> <p>2018-06-01</p> <p>The identification of groups of ligands binding metals is a crucial issue for the better understanding of their bioaccessibility. In the current study, we have intended an approach for identification of Zn-binding ligands based on using capillary electrophoresis combined with inductively coupled plasma mass spectrometry (CE-ICP-MS) and tandem electrospray ionization mass spectrometry (CE-ESI-MS/MS). The approach, which featured the use of the coupling of capillary electrophoresis with inductively coupled plasma mass spectrometry allows to separate and observe zinc ions present in complexes with respect to their size and charge and to identify nine compounds with zinc isotopic profile. CE-ICP-MS provides us with information about presence of zinc species and elemental information about zinc distribution. CE-ESI-MS/MS provide us with information about the most favorable Zn binding ligands: amino acids, flavonols, stilbenoids, <span class="hlt">fenolic</span> acids and carotenoids. The presented work is the continuation of previous studies based on using LC-ESI-MS/MS, though, now we presented a new solutions with the possibility of changing detectors without changing the separation techniques, what is important without re-optimizing the method. The new presented method allows to identify the zinc-binding ligands in shorter time. Copyright © 2018 Elsevier B.V. All rights reserved.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5402325','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5402325"><span>Remisión de aneurisma luego de exéresis de MAV <span class="hlt">con</span> aparición de síndrome del acento extranjero</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Sosa, Fidel; Bustamante, Jorge; Rodríguez, Facundo; Argañaraz, Romina; Rubino, Pablo; Lambre, Jorge</p> <p>2017-01-01</p> <p>Resumen Introducción: Los aneurismas asociados a malformaciones arteriovenosas (MAV) son lesiones vasculares que suelen encontrarse hasta en el 15% de los casos, incrementando el riesgo global de hemorragia. La conducta frente a los aneurismas asociados es dicotómica en la literatura, mientras existen reportes de la desaparición de los mismos luego de la exéresis de la MAV, otros artículos enfatizan su tratamiento precoz. El síndrome del acento extranjero es un raro trastorno neurológico en el que el paciente habla su lengua materna como lo haría una persona extranjera y suena <span class="hlt">con</span> “acento” extranjero a oídos de los oyentes nativos. Objetivo: Presentar un paciente que desarrolla el síndrome del acento extranjero posterior a la exéresis de una MAV y la evolución de un aneurisma asociado. Presentación de caso: Paciente pediátrico que luego de la exéresis de una MAV fronto-opercular posterior izquierda remite por completo un aneurisma de hiperflujo asociado, presentando en el postquirúrgico el síndrome del acento extranjero. Conclusión: Queda reportado el caso de este raro síndrome y la resolución espontánea de un aneurisma proximal luego de la exéresis de una MAV. PMID:28480115</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28870540','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28870540"><span><span class="hlt">CON</span>4EI: Slug Mucosal Irritation (SMI) test method for hazard identification and labelling of serious eye damaging and eye irritating chemicals.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Adriaens, E; Guest, R; Willoughby, J A; Fochtman, P; Kandarova, H; Verstraelen, S; Van Rompay, A R</p> <p>2018-06-01</p> <p>Assessment of ocular irritancy is an international regulatory requirement in the safety evaluation of industrial and consumer products. Although many in vitro ocular irritation assays exist, alone they are incapable of fully categorizing chemicals. The objective of CEFIC-LRI-AIMT6-VITO <span class="hlt">CON</span>4EI (CONsortium for in vitro Eye Irritation testing strategy) project was to develop tiered testing strategies for eye irritation assessment that can lead to complete replacement of the in vivo Draize rabbit eye test (OECD TG 405). A set of 80 reference chemicals was tested with seven test methods, one method was the Slug Mucosal Irritation (SMI) test method. The method measures the amount of mucus produced (MP) during a single 1-hour contact with a 1% and 10% dilution of the chemical. Based on the total MP, a classification (Cat 1, Cat 2, or No Cat) is predicted. The SMI test method correctly identified 65.8% of the Cat 1 chemicals with a specificity of 90.5% (low over-prediction rate for in vivo Cat 2 and No Cat chemicals). Mispredictions were predominantly unidirectional towards lower classifications with 26.7% of the liquids and 40% of the solids being underpredicted. In general, the performance was better for liquids than for solids with respectively 76.5% vs 57.1% (Cat 1), 61.5% vs 50% (Cat 2), and 87.5% vs 85.7% (No Cat) being identified correctly. Copyright © 2017 Elsevier Ltd. All rights reserved.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/20307675','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/20307675"><span>Divergence times and colonization of the Canary Islands by Gallotia lizards.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Cox, Siobhan C; Carranza, Salvador; Brown, Richard P</p> <p>2010-08-01</p> <p> show that G. galloti is likely to have colonized La Palma more than 0.5 Ma after emergence of the island 1.77 mya, while G. caesaris from the same clade may have colonized El <span class="hlt">Hierro</span> very soon after it emerged 1.12 mya. There are tentative indications that the large-bodied endangered G. simonyi colonized El <span class="hlt">Hierro</span> around the same time or even later than the smaller-bodied G. caesaris. This study demonstrates the effectiveness of Bayesian dating of a phylogeny in helping reconstruct the historical pattern of dispersal across an oceanic archipelago. Copyright 2010 Elsevier Inc. All rights reserved.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5141515','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5141515"><span>The pros and <span class="hlt">cons</span> of ecological risk assessment based on data from different levels of biological organization</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Rohr, Jason R.; Salice, Christopher J.; Nisbet, Roger M.</p> <p>2016-01-01</p> <p>Ecological risk assessment (ERA) is the process used to evaluate the safety of manufactured chemicals to the environment. Here we review the pros and <span class="hlt">cons</span> of ERA across levels of biological organization, including suborganismal (e.g. biomarkers), individual, population, community, ecosystem, and landscapes levels. Our review revealed that level of biological organization is often related negatively with ease at assessing cause-effect relationships, ease of high-throughput screening of large numbers of chemicals (it is especially easier for suborganismal endpoints), and uncertainty of the ERA because low levels of biological organization tend to have a large distance between their measurement (what is quantified) and assessment endpoints (what is to be protected). In contrast, level of biological organization is often related positively with sensitivity to important negative and positive feedbacks and context dependencies within biological systems, and ease at capturing recovery from adverse contaminant effects. Some endpoints did not show obvious trends across levels of biological organization, such as the use of vertebrate animals in chemical testing and ease at screening large numbers of species, and other factors lacked sufficient data across levels of biological organization, such as repeatability, variability, cost per study, and cost per species of effects assessment, the latter of which might be a more defensible way to compare costs of ERAs than cost per study. To compensate for weaknesses of ERA at any particular level of biological organization, we also review mathematical modeling approaches commonly used to extrapolate effects across levels of organization. Finally, we provide recommendations for next generation ERA, submitting that if there is an ideal level of biological organization to conduct ERA, it will only emerge if ERA is approached simultaneously from the bottom of biological organization up as well as from the top down, all while employing</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/29292104','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/29292104"><span>Statins: pros and <span class="hlt">cons</span>.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Pinal-Fernandez, Iago; Casal-Dominguez, Maria; Mammen, Andrew L</p> <p>2018-05-23</p> <p>Statins inhibit the critical step of cholesterol synthesis in which 3-hydroxy-3-methylglutaryl coenzyme A (HMGC) is transformed to mevalonate by the enzyme HMGC reductase. By doing so, they have a potent lipid-lowering effect that reduces cardiovascular risk and decreases mortality. Since the mevalonate pathway also influences endothelial function, the inflammatory response, and coagulation, the effects of statins reach well beyond their cholesterol lowering properties. As with all drugs, statins may have adverse effects; these include musculoskeletal symptoms, increased risk of diabetes, and higher rates of hemorrhagic stroke. However, the frequency of adverse effects is extremely low and, in selected patient populations, the benefits of statins considerably outweigh the potential risks. Published by Elsevier España, S.L.U.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://eric.ed.gov/?q=price&pg=7&id=EJ1026002','ERIC'); return false;" href="https://eric.ed.gov/?q=price&pg=7&id=EJ1026002"><span>Crossing the Rubric-<span class="hlt">Con</span></span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Bailey, James R.</p> <p>2014-01-01</p> <p>This essay engages the prospect and peril of employing rubrics in America. It discusses how institutional independence affects the enterprise, and addresses whether rubrics will be received as salvation or subservience by educational agents. It asks how rubrics can benefit stakeholders while examining their unintended consequences. It concludes by…</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li class="active"><span>25</span></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_25 --> <div class="footer-extlink text-muted" style="margin-bottom:1rem; text-align:center;">Some links on this page may take you to non-federal websites. 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