Sample records for field unit tailored

  1. Tailor-made force fields for crystal-structure prediction.

    PubMed

    Neumann, Marcus A

    2008-08-14

    A general procedure is presented to derive a complete set of force-field parameters for flexible molecules in the crystalline state on a case-by-case basis. The force-field parameters are fitted to the electrostatic potential as well as to accurate energies and forces generated by means of a hybrid method that combines solid-state density functional theory (DFT) calculations with an empirical van der Waals correction. All DFT calculations are carried out with the VASP program. The mathematical structure of the force field, the generation of reference data, the choice of the figure of merit, the optimization algorithm, and the parameter-refinement strategy are discussed in detail. The approach is applied to cyclohexane-1,4-dione, a small flexible ring. The tailor-made force field obtained for cyclohexane-1,4-dione is used to search for low-energy crystal packings in all 230 space groups with one molecule per asymmetric unit, and the most stable crystal structures are reoptimized in a second step with the hybrid method. The experimental crystal structure is found as the most stable predicted crystal structure both with the tailor-made force field and the hybrid method. The same methodology has also been applied successfully to the four compounds of the fourth CCDC blind test on crystal-structure prediction. For the five aforementioned compounds, the root-mean-square deviations between lattice energies calculated with the tailor-made force fields and the hybrid method range from 0.024 to 0.053 kcal/mol per atom around an average value of 0.034 kcal/mol per atom.

  2. Tailoring magnetostriction with various directions for directional solidification Fe82Ga15Al3 alloy by magnetic field heat treatment

    NASA Astrophysics Data System (ADS)

    Li, Xiaolong; Bao, Xiaoqian; Liu, Yangyang; Yu, Linhua; Li, Jiheng; Gao, Xuexu

    2017-10-01

    The magnetostriction of the Fe82Ga15Al3 alloy, along the length and width, can be tailored by applying a magnetic field heat treatment. In this work, the Fe82Ga15Al3 sheet was cut from the directional solidified Fe82Ga15Al3 alloy with the ⟨100⟩ preferred orientation and was annealed at 720 °C for 30 min under a magnetic field of 800 Oe along the length direction with a heating and cooling rate of 100 °C/min. The magnetostrictive properties along the length and width directions were modified to λ// = 7 ppm and λ⊥ = -210 ppm from λ// = 210 ppm and λ⊥ = -10 ppm for the initial sample prior to the magnetic field heat treatment. The cellular-like magnetic domain structure was composed of parallel 180° stripe domains and vertical 90° domains observed using a magnetic-force microscope. The change in magnetostriction along parallel and perpendicular directions was mainly resulted from the rotation of the magnetic domain units.

  3. Graphics Processing Units for HEP trigger systems

    NASA Astrophysics Data System (ADS)

    Ammendola, R.; Bauce, M.; Biagioni, A.; Chiozzi, S.; Cotta Ramusino, A.; Fantechi, R.; Fiorini, M.; Giagu, S.; Gianoli, A.; Lamanna, G.; Lonardo, A.; Messina, A.; Neri, I.; Paolucci, P. S.; Piandani, R.; Pontisso, L.; Rescigno, M.; Simula, F.; Sozzi, M.; Vicini, P.

    2016-07-01

    General-purpose computing on GPUs (Graphics Processing Units) is emerging as a new paradigm in several fields of science, although so far applications have been tailored to the specific strengths of such devices as accelerator in offline computation. With the steady reduction of GPU latencies, and the increase in link and memory throughput, the use of such devices for real-time applications in high-energy physics data acquisition and trigger systems is becoming ripe. We will discuss the use of online parallel computing on GPU for synchronous low level trigger, focusing on CERN NA62 experiment trigger system. The use of GPU in higher level trigger system is also briefly considered.

  4. United States Air Force Summer Research Program -- 1993. Volume 1. Program Management Report

    DTIC Science & Technology

    1993-12-01

    IEEE Spectrum and Physics Today. High school applicants can participate only in laboratories located no more than 20 miles from their residence. Tailored...faculty and $37/day for graduate students whose homes were more than 50 miles from the laboratory. Transportation to the laboratory at the beginning of...TX 78212- 7200 Branting, Luther Field: Dept of Computer Science Assistant Professor, PhD Laboratory: AL/HR PC Box 3682 University of Wyoming Vol-Page

  5. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Giovanni, D.V.; Carr, R.C.; Landham, E.C.

    Two products of coal quality research at the Electric Power Research Institute TM (EPRI) are available for field evaluation: Coal Quality Impact Model (CQIM and Fireside Testing Guidelines (FIG). The CQIM is a computer program that may be tailored to simulate the performance characteristics of a coal-fired power plant. The FIG is a technical report that guides utilities in conducting field tests to gather performance data and quantify the technical and economic impacts of different coals. Moreover, the results from field tests may be utilized to validate and assess the applicability of the CQIM. Field tests were conducted at Mississippimore » Power Company`s Watson Unit 4 to evaluate the coal quality impacts of coal switching on boiler performance and emissions. Watson Unit 4 is a 255 MW (gross), opposed-wall, pulverized-coal-fired boiler manufactured by Riley Stoker Corporation and rated at 1,779,000 lb/hr steam flow at 1000{degrees}F superheat steam temperature and 2,500 psig. The unit is equipped with a cold-side electrostatic precipitator for particulate matter control. Comprehensive tests were conducted on all major equipment components, including the pulverizers, fans, combustion equipment, boiler heat transfer surfaces, air preheater, and electrostatic precipitator, for two coals. The CQIN4 was configured to predict the performance of the unit when burning each coal. The work was sponsored by EPRI, and Mississippi Power Company (MPC) was the host utility company. This report summarizes results from the field test program, including potential heat rate improvements that were identified, and the differences in unit operations and performance for the two coals. The results from the CQIM validation effort are also presented.« less

  6. Shape-Tailorable Graphene-Based Ultra-High-Rate Supercapacitor for Wearable Electronics.

    PubMed

    Xie, Binghe; Yang, Cheng; Zhang, Zhexu; Zou, Peichao; Lin, Ziyin; Shi, Gaoquan; Yang, Quanhong; Kang, Feiyu; Wong, Ching-Ping

    2015-06-23

    With the bloom of wearable electronics, it is becoming necessary to develop energy storage units, e.g., supercapacitors that can be arbitrarily tailored at the device level. Although gel electrolytes have been applied in supercapacitors for decades, no report has studied the shape-tailorable capability of a supercapacitor, for instance, where the device still works after being cut. Here we report a tailorable gel-based supercapacitor with symmetric electrodes prepared by combining electrochemically reduced graphene oxide deposited on a nickel nanocone array current collector with a unique packaging method. This supercapacitor with good flexibility and consistency showed excellent rate performance, cycling stability, and mechanical properties. As a demonstration, these tailorable supercapacitors connected in series can be used to drive small gadgets, e.g., a light-emitting diode (LED) and a minimotor propeller. As simple as it is (electrochemical deposition, stencil printing, etc.), this technique can be used in wearable electronics and miniaturized device applications that require arbitrarily shaped energy storage units.

  7. Ultrashort polarization-tailored bichromatic fields from a CEP-stable white light supercontinuum.

    PubMed

    Kerbstadt, Stefanie; Timmer, Daniel; Englert, Lars; Bayer, Tim; Wollenhaupt, Matthias

    2017-05-29

    We apply ultrafast polarization shaping to an ultrabroadband carrier envelope phase (CEP) stable white light supercontinuum to generate polarization-tailored bichromatic laser fields of low-order frequency ratio. The generation of orthogonal linearly and counter-rotating circularly polarized bichromatic fields is achieved by introducing a composite polarizer in the Fourier plane of a 4 f polarization shaper. The resulting Lissajous- and propeller-type polarization profiles are characterized experimentally by cross-correlation trajectories. The scheme provides full control over all bichromatic parameters and allows for individual spectral phase modulation of both colors. Shaper-based CEP control and the generation of tailored bichromatic fields is demonstrated. These bichromatic CEP-stable polarization-shaped ultrashort laser pulses provide a versatile class of waveforms for coherent control experiments.

  8. Phase Space Tweezers for Tailoring Cavity Fields by Quantum Zeno Dynamics

    NASA Astrophysics Data System (ADS)

    Raimond, J. M.; Sayrin, C.; Gleyzes, S.; Dotsenko, I.; Brune, M.; Haroche, S.; Facchi, P.; Pascazio, S.

    2010-11-01

    We discuss an implementation of quantum Zeno dynamics in a cavity quantum electrodynamics experiment. By performing repeated unitary operations on atoms coupled to the field, we restrict the field evolution in chosen subspaces of the total Hilbert space. This procedure leads to promising methods for tailoring nonclassical states. We propose to realize “tweezers” picking a coherent field at a point in phase space and moving it towards an arbitrary final position without affecting other nonoverlapping coherent components. These effects could be observed with a state-of-the-art apparatus.

  9. Tailoring double Fano profiles with plasmon-assisted quantum interference in hybrid exciton-plasmon system

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhao, Dongxing; Wu, Jiarui; Gu, Ying, E-mail: ygu@pku.edu.cn

    2014-09-15

    We propose tailoring of the double Fano profiles via plasmon-assisted quantum interference in a hybrid exciton-plasmon system. Tailoring is performed by the interference between two exciton channels interacting with a common localized surface plasmon. Using an applied field of low intensity, the absorption spectrum of the hybrid system reveals a double Fano lineshape with four peaks. For relatively large field intensity, a broad flat window in the absorption spectrum appears which results from the destructive interference between excitons. Because of strong constructive interference, this window vanishes as intensity is further increased. We have designed a nanometer bandpass optical filter formore » visible light based on tailoring of the optical spectrum. This study provides a platform for quantum interference that may have potential applications in ultracompact tunable quantum devices.« less

  10. Multiply charged ion generation according to magnetic field configurations in Hall thruster plasmas

    NASA Astrophysics Data System (ADS)

    Kim, Holak; Lee, Seunghun; Kim, Junbum; Lim, Youbong; Choe, Wonho; KIMS Collaboration

    2016-09-01

    Plasma propulsion is the most promising techniques to operate satellites for low earth orbit as well as deep space exploration. A typical plasma propulsion system is Hall thruster (HT) that uses crossed electromagnetic fields to ionize a propellant gas and to accelerate the ionized gas. In HT the tailoring of magnetic fields is significant due to that the electron confinement in the electromagnetic fields affects thruster performances such as thrust force, specific impulse, power efficiency, and life time. We designed an anode layer HT (TAL) with the magnetic field tailoring. The TAL is possible to keep discharge in 1 2 kilovolts, which voltage is useful to obtain high specific impulse The magnetic field tailoring is adapted to minimize undesirable heat dissipations and secondary electron emissions at a wall surrounding plasma In presentation, we will report TAL performances including thrust force, specific impulse, and anode efficiency measured by a pendulum thrust stand. This mechanical measurement will be compared to the plasma diagnostics conducted by angular Faraday probe, retarding potential analyzer, and ExB probe Grant No. 2014M1A3A3A02034510.

  11. Tailored vectorial light fields: flower, spider web and hybrid structures

    NASA Astrophysics Data System (ADS)

    Otte, Eileen; Alpmann, Christina; Denz, Cornelia

    2017-04-01

    We present the realization and analysis of tailored vector fields including polarization singularities. The fields are generated by a holographic method based on an advanced system including a spatial light modulator. We demonstrate our systems capabilities realizing specifically customized vector fields including stationary points of defined polarization in its transverse plane. Subsequently, vectorial flowers and spider webs as well as unique hybrid structures of these are introduced, and embedded singular points are characterized. These sophisticated light fields reveal attractive properties that pave the way to advanced application in e.g. optical micromanipulation. Beyond particle manipulation, they contribute essentially to actual questions in singular optics.

  12. Magnetic Field Tailored Annular Hall Thruster with Anode Layer

    NASA Astrophysics Data System (ADS)

    Lee, Seunghun; Kim, Holak; Kim, Junbum; Lim, Youbong; Choe, Wonho; Korea Institute of Materials Science Collaboration

    2016-09-01

    Plasma propulsion system is one of the key components for advanced missions of satellites as well as deep space exploration. A typical plasma propulsion system is Hall effect thruster that uses crossed electric and magnetic fields to ionize a propellant gas and to accelerate the ionized gas to generate momentum. In Hall thruster plasmas, magnetic field configuration is important due to the fact that electron confinement in the electromagnetic fields affects both plasma and ion beam characteristics as well as thruster performance parameters including thrust, specific impulse, power efficiency, and life time. In this work, development of an anode layer Hall thruster (TAL) with magnetic field tailoring has been attempted. The TAL is possible to keep discharge in 1 to 2 kilovolts of anode voltage, which is useful to obtain high specific impulse. The magnetic field tailoring is used to minimize undesirable heat dissipation and secondary electron emission from the wall surrounding the plasma. We will report 3 W and 200 W thrusters performances measured by a pendulum thrust stand according to the magnetic field configuration. Also, the measured result will be compared with the plasma diagnostics conducted by an angular Faraday probe, a retarding potential analyzer, and a ExB probe.

  13. Can tailored interventions increase mammography use among HMO women?

    PubMed

    Lipkus, I M; Rimer, B K; Halabi, S; Strigo, T S

    2000-01-01

    Telephone counseling and tailored print communications have emerged as promising methods for promoting mammography screening. However, there has been little research testing, within the same randomized field trial, of the efficacy of these two methods compared to a high-quality usual care system for enhancing screening. This study addressed the question: Compared to usual care, is tailored telephone counseling more effective than tailored print materials for promoting mammography screening? Three-year randomized field trial. One thousand ninety-nine women aged 50 and older recruited from a health maintenance organization in North Carolina. Women were randomized to 1 of 3 groups: (1) usual care, (2) tailored print communications, and (3) tailored telephone counseling. Adherence to mammography screening based on self-reports obtained during 1995, 1996, and 1997. Compared to usual care alone, telephone counseling promoted a significantly higher proportion of women having mammograms on schedule (71% vs 61%) than did tailored print (67% vs 61%) but only after the first year of intervention (during 1996). Furthermore, compared to usual care, telephone counseling was more effective than tailored print materials at promoting being on schedule with screening during 1996 and 1997 among women who were off-schedule during the previous year. The effects of the intervention were most pronounced after the first intervention. Compared to usual care, telephone counseling seemed particularly effective at promoting change among nonadherent women, the group for whom the intervention was developed. These results suggest that telephone counseling, rather than tailored print, might be the preferred first-line intervention for getting nonadherent women on schedule for mammography screening. Many questions would have to be answered about why the tailored print intervention was not more powerful. Nevertheless, it is clear that additional interventions will be needed to maintain women's adherence to mammography. Medical Subject Headings (MeSH): mammography screening, telephone counseling, tailored print communications, barriers.

  14. A Brief Culturally Tailored Intervention for Puerto Ricans with Type 2 Diabetes

    ERIC Educational Resources Information Center

    Osborn, Chandra Y.; Amico, K. R.; Cruz, Noemi; O'Connell, Ann A.; Perez-Escamilla, Rafael; Kalichman, Seth C.; Wolf, Scott A.; Fisher, Jeffrey D.

    2010-01-01

    The information-motivation-behavioral skills (IMB) model of health behavior change informed the design of a brief, culturally tailored diabetes self-care intervention for Puerto Ricans with type 2 diabetes. Participants (n = 118) were recruited from an outpatient, primary care clinic at an urban hospital in the northeast United States. ANCOVA…

  15. Aerogels in Chemical Engineering: Strategies Toward Tailor-Made Aerogels.

    PubMed

    Smirnova, Irina; Gurikov, Pavel

    2017-06-07

    The present review deals with recent advances in the rapidly growing field of aerogel research and technology. The major focus of the review lies in approaches that allow tailoring of aerogel properties to meet application-driven requirements. The decisive properties of aerogels are discussed with regard to existing and potential application areas. Various tailoring strategies, such as modulation of the pore structure, coating, surface modification, and post-treatment, are illustrated by results of the last decade. In view of commercialization of aerogel-based products, a panorama of current industrial aerogel suppliers is given, along with a discussion of possible alternative sources for raw materials and precursors. Finally, growing points and perspectives of the aerogel field are summarized.

  16. Arbitrary optical wavefront shaping via spin-to-orbit coupling

    NASA Astrophysics Data System (ADS)

    Larocque, Hugo; Gagnon-Bischoff, Jérémie; Bouchard, Frédéric; Fickler, Robert; Upham, Jeremy; Boyd, Robert W.; Karimi, Ebrahim

    2016-12-01

    Converting spin angular momentum to orbital angular momentum has been shown to be a practical and efficient method for generating optical beams carrying orbital angular momentum and possessing a space-varying polarized field. Here, we present novel liquid crystal devices for tailoring the wavefront of optical beams through the Pancharatnam-Berry phase concept. We demonstrate the versatility of these devices by generating an extensive range of optical beams such as beams carrying ±200 units of orbital angular momentum along with Bessel, Airy and Ince-Gauss beams. We characterize both the phase and the polarization properties of the generated beams, confirming our devices’ performance.

  17. Organisation Development through Management Development: The United Biscuits Example.

    ERIC Educational Resources Information Center

    Campbell, Andrew; Winterburn, Den

    1988-01-01

    The success of the strategic management program developed by United Biscuits (United Kingdom) for senior managers resulted from (1) tailoring the program to organizational and individual needs; (2) using company-specific material; (3) involving top management; and (4) using a follow-up program. (JOW)

  18. Vibroacoustic Tailoring of a Rod-Stiffened Composite Fuselage Panel with Multidisciplinary Considerations

    NASA Technical Reports Server (NTRS)

    Allen, Albert R.; Przekop, Adam

    2015-01-01

    An efficient multi-objective design tailoring procedure seeking to improve the vibroacoustic performance of a fuselage panel while maintaining or reducing weight is presented. The structure considered is the pultruded rod stitched efficient unitized structure, a highly integrated composite structure concept designed for a noncylindrical, next-generation flight vehicle fuselage. Modifications to a baseline design are evaluated within a six-parameter design space including spacing, flange width, and web height for both frame and stringer substructure components. The change in sound power radiation attributed to a design change is predicted using finite-element models sized and meshed for analyses in the 500 Hz, 1 kHz, and 2 kHz octave bands. Three design studies are carried out in parallel while considering a diffuse acoustic field excitation and two types of turbulent boundary-layer excitation. Kriging surrogate models are used to reduce the computational costs of resolving the vibroacoustic and weight objective Pareto fronts. The resulting Pareto optimal designs are then evaluated under a static pressurization ultimate load to assess structural strength and stability. Results suggest that choosing alternative configurations within the considered design space can reduce weight and improve vibroacoustic performance without compromising strength and stability of the structure under the static load condition considered, but the tradeoffs are significantly influenced by the spatial characteristics of the assumed excitation field.

  19. "She Gave Me the Confidence to Open Up": Bridging Communication by Promotoras in a Childhood Obesity Intervention for Latino Families

    ERIC Educational Resources Information Center

    Falbe, Jennifer; Friedman, Lily E.; Sokal-Gutierrez, Karen; Thompson, Hannah R.; Tantoco, Nicole K.; Madsen, Kristine A.

    2017-01-01

    Childhood obesity is a public health threat that disproportionally affects Latino youth in the United States. Active and Healthy Families (AHF) is a culturally tailored, family-based program for addressing obesity disparities in a predominantly immigrant Latino population. AHF was the first primary care, culturally tailored intervention for Latino…

  20. Tailored Fano resonance and localized electromagnetic field enhancement in Ag gratings

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Li, Zhaozhu; Klopf, J. Michael; Wang, Lei

    Metallic gratings can support Fano resonances when illuminated with EM radiation, and their characteristic reflectivity versus incident angle lineshape can be greatly affected by the surrounding dielectric environment and the grating geometry. By using conformal oblique incidence thin film deposition onto an optical grating substrate, it is possible to increase the grating amplitude due to shadowing effects, thereby enabling tailoring of the damping processes and electromagnetic field couplings of the Fano resonances, hence optimizing the associated localized electric field intensity. To investigate these effects we compare the optical reflectivity under resonance excitation in samples prepared by oblique angle deposition (OAD)more » and under normal deposition (ND) onto the same patterned surfaces. We observe that by applying OAD method, the sample exhibits a deeper and narrower reflectivity dip at resonance than that obtained under ND. This can be explained in terms of a lower damping of Fano resonance on obliquely deposited sample and leads to a stronger localized electric field. This approach opens a fabrication path for applications where tailoring the electromagnetic field induced by Fano resonance can improve the figure of merit of specific device characteristics, e.g. quantum efficiency (QE) in grating-based metallic photocathodes.« less

  1. Tailored Fano resonance and localized electromagnetic field enhancement in Ag gratings

    DOE PAGES

    Li, Zhaozhu; Klopf, J. Michael; Wang, Lei; ...

    2017-03-14

    Metallic gratings can support Fano resonances when illuminated with EM radiation, and their characteristic reflectivity versus incident angle lineshape can be greatly affected by the surrounding dielectric environment and the grating geometry. By using conformal oblique incidence thin film deposition onto an optical grating substrate, it is possible to increase the grating amplitude due to shadowing effects, thereby enabling tailoring of the damping processes and electromagnetic field couplings of the Fano resonances, hence optimizing the associated localized electric field intensity. To investigate these effects we compare the optical reflectivity under resonance excitation in samples prepared by oblique angle deposition (OAD)more » and under normal deposition (ND) onto the same patterned surfaces. We observe that by applying OAD method, the sample exhibits a deeper and narrower reflectivity dip at resonance than that obtained under ND. This can be explained in terms of a lower damping of Fano resonance on obliquely deposited sample and leads to a stronger localized electric field. This approach opens a fabrication path for applications where tailoring the electromagnetic field induced by Fano resonance can improve the figure of merit of specific device characteristics, e.g. quantum efficiency (QE) in grating-based metallic photocathodes.« less

  2. Another Look at the Draft Mil-Std-1540E Unit Random Vibration Test Requirements

    NASA Astrophysics Data System (ADS)

    Perl, E.; Peterson, A. J..; Davis, D.

    2012-07-01

    The draft Mil-Std-1540E has been updated to reflect lessons learned since its publication as an SMC Standard in 2008, [1], and an earlier Aerospace Corporation Technical Report released in 2006, [2]. This paper discusses the technical rationale supporting some of the unit random vibration test requirements to provide better insight into their derivation and application to programs. It is intended that these requirements be tailored for each program to reflect the customer risk profile. Several tailoring options are provided and a two phase test strategy is discussed to highlight its applicability to utilizing heritage hardware in new applications.

  3. High field terahertz pulse generation from plasma wakefield driven by tailored laser pulses

    NASA Astrophysics Data System (ADS)

    Chen, Zi-Yu

    2013-06-01

    A scheme to generate high field terahertz (THz) pulses by using tailored laser pulses interaction with a gas target is proposed. The laser wakefield based THz source is emitted from the asymmetric laser shape induced plasma transverse transient net currents. Particle-in-cell simulations show that THz emission with electric filed strength over 1 GV/cm can be obtained with incident laser at 1×1019 W/cm2 level, and the corresponding energy conversion efficiency is more than 10-4. The intensity scaling holds up to high field strengths. Such a source also has a broad tunability range in amplitude, frequency spectra, and temporal shape.

  4. Bias field tailored plasmonic nano-electrode for high-power terahertz photonic devices

    PubMed Central

    Moon, Kiwon; Lee, Il-Min; Shin, Jun-Hwan; Lee, Eui Su; Kim, Namje; Lee, Won-Hui; Ko, Hyunsung; Han, Sang-Pil; Park, Kyung Hyun

    2015-01-01

    Photoconductive antennas with nano-structured electrodes and which show significantly improved performances have been proposed to satisfy the demand for compact and efficient terahertz (THz) sources. Plasmonic field enhancement was previously considered the dominant mechanism accounting for the improvements in the underlying physics. However, we discovered that the role of plasmonic field enhancement is limited and near-field distribution of bias field should be considered as well. In this paper, we clearly show that the locally enhanced bias field due to the size effect is much more important than the plasmonic enhanced absorption in the nano-structured electrodes for the THz emitters. Consequently, an improved nano-electrode design is presented by tailoring bias field distribution and plasmonic enhancement. Our findings will pave the way for new perspectives in the design and analysis of plasmonic nano-structures for more efficient THz photonic devices. PMID:26347288

  5. Bias field tailored plasmonic nano-electrode for high-power terahertz photonic devices.

    PubMed

    Moon, Kiwon; Lee, Il-Min; Shin, Jun-Hwan; Lee, Eui Su; Kim, Namje; Lee, Won-Hui; Ko, Hyunsung; Han, Sang-Pil; Park, Kyung Hyun

    2015-09-08

    Photoconductive antennas with nano-structured electrodes and which show significantly improved performances have been proposed to satisfy the demand for compact and efficient terahertz (THz) sources. Plasmonic field enhancement was previously considered the dominant mechanism accounting for the improvements in the underlying physics. However, we discovered that the role of plasmonic field enhancement is limited and near-field distribution of bias field should be considered as well. In this paper, we clearly show that the locally enhanced bias field due to the size effect is much more important than the plasmonic enhanced absorption in the nano-structured electrodes for the THz emitters. Consequently, an improved nano-electrode design is presented by tailoring bias field distribution and plasmonic enhancement. Our findings will pave the way for new perspectives in the design and analysis of plasmonic nano-structures for more efficient THz photonic devices.

  6. Tailoring and field-testing the use of a knowledge translation peer support shared decision making strategy with First Nations, Inuit and Métis people making decisions about their cancer care: a study protocol.

    PubMed

    Jull, Janet; Mazereeuw, Maegan; Sheppard, Amanada; Kewayosh, Alethea; Steiner, Richard; Graham, Ian D

    2018-01-01

    Tailoring and testing a peer support decision making strategy with First Nations, Inuit and Métis people making decisions about their cancer care: A study protocol.First Nations, Inuit and Métis (FNIM) people face higher risks for cancer compared to non-FNIM populations. They also face cultural barriers to health service use. Within non-FNIM populations an approach to health decision making, called shared decision making (SDM), has been found to improve the participation of people in their healthcare. Peer support with SDM further improves these benefits. The purpose of this study is to tailor and test a peer support SDM strategy with community support workers to increase FNIM people's participation in their cancer care.This project has two phases that will be designed and conducted with a Steering Committee that includes members of the FNIM and cancer care communities. First, a peer support SDM strategy will be tailored to meet the needs of cancer system users who are receiving care in urban settings, and training in the SDM strategy developed for community support workers. Three communities will be supported for participation in the study and community support workers who are peers from each community will be trained to use the SDM strategy.Next, each community support worker will work with a community member who has a diagnosis of cancer or who has supported a family member with cancer. Each community support worker and community member pair will use the SDM strategy. The participation and experience of the community support worker and community member will be evaluated.The research will be used to develop strategies to support people who are making decisions about their health. Tailoring and field-testing the use of a knowledge translation peer support shared decision making strategy with First Nations, Inuit and Métis people making decisions about their cancer care: A study protocol Background First Nations, Inuit and Métis ("FNIM") people face increased cancer risks in relation to general populations and experience barriers to health service use. Shared decision making (SDM) has been found to improve peoples' participation and outcomes in healthcare and peer support with SDM further improves these benefits. The purpose of this study is to tailor and then field test, by and with FNIM communities, a peer support SDM strategy for use in cancer care. Methods This project has 2 theory-driven phases and 5 stages (a-e). A core research team that includes members of the Aboriginal Cancer Control Unit of Cancer Care Ontario communities and academic researchers, will work with a Steering Committee. In phase 1 , (stage a) a peer support SDM strategy will be tailored to meet the needs of cancer system users who are receiving care in urban settings and (stage b), training developed that will i) introduce participant communities to SDM, and ii) train community support workers (CSWs) within these communities. Next (stage c), three communities will be approached for voluntary participation in the study. These communities will be introduced to SDM in community meetings, and if in agreement then CSWs from each community will be recruited to participate in the study. One volunteer CSW from each community will be trained to use the peer support SDM strategy to enable phase 2 (field test of the peer support SDM strategy).During phase 2 (stage d), each CSW will be matched to a volunteer community member who has had a diagnosis of cancer or has supported a family member with cancer and is familiar with Ontario cancer systems. Each CSW-community member pair (3 to 4 pairs/community) will use the tailored peer support SDM strategy; their interaction will be audio-recorded and their participation and experience evaluated (total of 9 to 12 interviews). As well (stage e), data will be collected on health systems' factors related to the use of the peer support SDM strategy. Discussion Findings will develop peer support SDM strategies to enhance participation of FNIM people in cancer care decisions, advance knowledge translation science, and support a proposal to conduct a multi-site implementation trial.

  7. Cost-effectiveness of targeted and tailored interventions on colorectal cancer screening use.

    PubMed

    Lairson, David R; DiCarlo, Melissa; Myers, Ronald E; Wolf, Thomas; Cocroft, James; Sifri, Randa; Rosenthal, Michael; Vernon, Sally W; Wender, Richard

    2008-02-15

    Colorectal cancer (CRC) screening is cost-effective but underused. The objective of this study was to determine the cost-effectiveness of targeted and tailored behavioral interventions to increase CRC screening use by conducting an economic analysis associated with a randomized trial among patients in a large, racially and ethnically diverse, urban family practice in Philadelphia. The incremental costs per unit increase were measured in individuals who were screened during the 24 months after intervention. Percent increase in screening was adjusted for baseline differences in the study groups. Each intervention arm received a targeted screening invitation letter, stool blood test (SBT) cards, informational booklet, and reminder letter. Tailored interventions incrementally added tailored messages and reminder telephone calls. Program costs of the targeted intervention were 42 dollars per participant. Additional costs of adding tailored print materials and of delivering a reminder telephone call were 150 dollars and 200 dollars per participant, respectively. The cost per additional individual screened was 319 dollars when comparing the no intervention group with the targeted intervention group. The targeted intervention was more effective and less costly than the tailored intervention. Although tailoring plus reminder telephone call was the most effective strategy, it was very costly per additional individual screened. Mailed SBT cards significantly boosted CRC screening use. However, going beyond the targeted intervention to include tailoring or tailoring plus reminder calls in the manner used in this study did not appear to be an economically attractive strategy. Cancer 2008. (c) 2007 American Cancer Society.

  8. Toward broadband, dynamic structuring of a complex plasmonic field.

    PubMed

    Wei, Shibiao; Si, Guangyuan; Malek, Michael; Earl, Stuart K; Du, Luping; Kou, Shan Shan; Yuan, Xiaocong; Lin, Jiao

    2018-06-01

    The ability to tailor a coherent surface plasmon polariton (SPP) field is an important step toward many new opportunities for a broad range of nanophotonic applications. Previously, both scanning a converging SPP spot and designing SPP profiles using an ensemble of spots have been demonstrated. SPPs, however, are normally excited by intense, coherent light sources, that is, lasers. Hence, interference between adjacent spots is inevitable and will affect the overall SPP field distributions. We report a reconfigurable and wavelength-independent platform for generating a tailored two-dimensional (2D) SPP field distribution by considering the coherent field as a whole rather than as individual spots. With this new approach, the inherent constraints in a 2D coherent field distribution are revealed. Our design approach works not only for SPP waves but also for other 2D wave systems such as surface acoustic waves.

  9. Habitat Demonstration Unit (HDU) Pressurized Excursion Module (PEM) Systems Integration Strategy

    NASA Technical Reports Server (NTRS)

    Gill, Tracy; Merbitz, Jerad; Kennedy, Kriss; Tri, Terry; Toups, Larry; Howe, A. Scott

    2011-01-01

    The Habitat Demonstration Unit (HDU) project team constructed an analog prototype lunar surface laboratory called the Pressurized Excursion Module (PEM). The prototype unit subsystems were integrated in a short amount of time, utilizing a rapid prototyping approach that brought together over 20 habitation-related technologies from a variety of NASA centers. This paper describes the system integration strategies and lessons learned, that allowed the PEM to be brought from paper design to working field prototype using a multi-center team. The system integration process was based on a rapid prototyping approach. Tailored design review and test and integration processes facilitated that approach. The use of collaboration tools including electronic tools as well as documentation enabled a geographically distributed team take a paper concept to an operational prototype in approximately one year. One of the major tools used in the integration strategy was a coordinated effort to accurately model all the subsystems using computer aided design (CAD), so conflicts were identified before physical components came together. A deliberate effort was made following the deployment of the HDU PEM for field operations to collect lessons learned to facilitate process improvement and inform the design of future flight or analog versions of habitat systems. Significant items within those lessons learned were limitations with the CAD integration approach and the impact of shell design on flexibility of placing systems within the HDU shell.

  10. How to conduct a qualitative meta-analysis: Tailoring methods to enhance methodological integrity.

    PubMed

    Levitt, Heidi M

    2018-05-01

    Although qualitative research has long been of interest in the field of psychology, meta-analyses of qualitative literatures (sometimes called meta-syntheses) are still quite rare. Like quantitative meta-analyses, these methods function to aggregate findings and identify patterns across primary studies, but their aims, procedures, and methodological considerations may vary. This paper explains the function of qualitative meta-analyses and their methodological development. Recommendations have broad relevance but are framed with an eye toward their use in psychotherapy research. Rather than arguing for the adoption of any single meta-method, this paper advocates for considering how procedures can best be selected and adapted to enhance a meta-study's methodological integrity. Through the paper, recommendations are provided to help researchers identify procedures that can best serve their studies' specific goals. Meta-analysts are encouraged to consider the methodological integrity of their studies in relation to central research processes, including identifying a set of primary research studies, transforming primary findings into initial units of data for a meta-analysis, developing categories or themes, and communicating findings. The paper provides guidance for researchers who desire to tailor meta-analytic methods to meet their particular goals while enhancing the rigor of their research.

  11. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Voyles, J. W.; Chapman, L. A.

    This document establishes a common set of guidelines for the Atmospheric Radiation Measurement (ARM) Climate Research Facility for planning, executing, and closing out field campaigns. The steps that guide individual field campaigns are described in the Field Campaign Tracking System and are specifically tailored to meet the scope of each field campaign.

  12. Tailoring magnetic field gradient design to magnet cryostat geometry.

    PubMed

    Trakic, A; Liu, F; Lopez, H S; Wang, H; Crozier, S

    2006-01-01

    Eddy currents induced within a magnetic resonance imaging (MRI) cryostat bore during pulsing of gradient coils can be applied constructively together with the gradient currents that generate them, to obtain good quality gradient uniformities within a specified imaging volume over time. This can be achieved by simultaneously optimizing the spatial distribution and temporal pre-emphasis of the gradient coil current, to account for the spatial and temporal variation of the secondary magnetic fields due to the induced eddy currents. This method allows the tailored design of gradient coil/magnet configurations and consequent engineering trade-offs. To compute the transient eddy currents within a realistic cryostat vessel, a low-frequency finite-difference time-domain (FDTD) method using total-field scattered-field (TFSF) scheme has been performed and validated.

  13. Guidelines for Adult Basic Education Volunteers.

    ERIC Educational Resources Information Center

    Leppert, Alice M.

    This booklet contains suggestions for creating an effective, "custom-made" local unit of volunteers, using the educational and social action resources of the community for volunteer training. The suggestions are tailored to fit the flexible mode of operation of Church Women United in a wide variety of communities. The statements related…

  14. A tailored educational intervention improves doctor's performance in managing depression: a randomized controlled trial.

    PubMed

    Shirazi, Mandana; Lonka, Kirsti; Parikh, Sagar V; Ristner, Gunilla; Alaeddini, Farshid; Sadeghi, Majid; Wahlstrom, Rolf

    2013-02-01

    To assess the effects of a tailored and activating educational intervention, based on a three-stage modified Prochaska model of readiness-to-change, on the performance of general physicians in primary care (GPs) regarding management of depressive disorders. Parallel group, randomized control trial. Primary hypothesis was that performance would improve by 20 percentage units in the intervention arm. The setting was primary care in southern Tehran. The participants were 192 GPs stratified on stage of readiness-to-change, sex, age and work experience. The intervention was a 2-day interactive workshop for a small group of GPs' at a higher stage of readiness-to-change ('intention') and a 2-day interactive large group meeting for those with lower propensity to change ('attitude') at the pre-assessment. GPs in the control arm participated in a standard educational programme on the same topic. The main outcome measures were validated tools to assess GPs' performance by unannounced standardized patients, regarding diagnosis and treatment of depressive disorders. The assessments were made 2 months before and 2 months after the intervention. GPs in the intervention arm significantly improved their overall mean scores for performance regarding both diagnosis, with an intervention effect of 14 percentage units (P = 0.007), and treatment and referral, with an intervention effect of 20 percentage units (P < 0.0001). The largest improvement after the intervention appeared in the small group: 30 percentage units for diagnosis (P = 0.027) and 29 percentage units for treatment and referral (P < 0.0001). Activating learning methods, tailored according to the participants' readiness to change, improved clinical performance of GPs in continuing medical education and can be recommended for continuing professional development. © 2011 Blackwell Publishing Ltd.

  15. Tailored optical vector fields for ultrashort-pulse laser induced complex surface plasmon structuring.

    PubMed

    Ouyang, J; Perrie, W; Allegre, O J; Heil, T; Jin, Y; Fearon, E; Eckford, D; Edwardson, S P; Dearden, G

    2015-05-18

    Precise tailoring of optical vector beams is demonstrated, shaping their focal electric fields and used to create complex laser micro-patterning on a metal surface. A Spatial Light Modulator (SLM) and a micro-structured S-waveplate were integrated with a picosecond laser system and employed to structure the vector fields into radial and azimuthal polarizations with and without a vortex phase wavefront as well as superposition states. Imprinting Laser Induced Periodic Surface Structures (LIPSS) elucidates the detailed vector fields around the focal region. In addition to clear azimuthal and radial plasmon surface structures, unique, variable logarithmic spiral micro-structures with a pitch Λ ∼1μm, not observed previously, were imprinted on the surface, confirming unambiguously the complex 2D focal electric fields. We show clearly also how the Orbital Angular Momentum(OAM) associated with a helical wavefront induces rotation of vector fields along the optic axis of a focusing lens and confirmed by the observed surface micro-structures.

  16. Transfer of Magnetic Order and Anisotropy through Epitaxial Integration of 3d and 4f Spin Systems.

    PubMed

    Bluschke, M; Frano, A; Schierle, E; Minola, M; Hepting, M; Christiani, G; Logvenov, G; Weschke, E; Benckiser, E; Keimer, B

    2017-05-19

    Resonant x-ray scattering at the Dy M_{5} and Ni L_{3} absorption edges was used to probe the temperature and magnetic field dependence of magnetic order in epitaxial LaNiO_{3}-DyScO_{3} superlattices. For superlattices with 2 unit cell thick LaNiO_{3} layers, a commensurate spiral state develops in the Ni spin system below 100 K. Upon cooling below T_{ind}=18  K, Dy-Ni exchange interactions across the LaNiO_{3}-DyScO_{3} interfaces induce collinear magnetic order of interfacial Dy moments as well as a reorientation of the Ni spins to a direction dictated by the strong magnetocrystalline anisotropy of Dy. This transition is reversible by an external magnetic field of 3 T. Tailored exchange interactions between rare-earth and transition-metal ions thus open up new perspectives for the manipulation of spin structures in metal-oxide heterostructures and devices.

  17. Tailored composite wings with elastically produced chordwise camber

    NASA Technical Reports Server (NTRS)

    Rehfield, Lawrence W.; Chang, Stephen; Zischka, Peter J.; Pickings, Richard D.; Holl, Michael W.

    1991-01-01

    Four structural concepts were created which produce chordwise camber deformation that results in enhanced lift. A wing box can be tailored to utilize each of these with composites. In attempting to optimize the aerodynamic benefits, researchers found that there are two optimum designs that are of interest. There is a weight optimum which corresponds to the maximum lift per unit structural weight. There is also a lift optimum that corresponds to maximum absolute lift. Experience indicates that a large weight penalty accompanies the transition from weight to lift optimum designs. New structural models, the basic deformation mechanisms that are utilized, and typical analytical results are presented. It appears that lift enhancements of sufficient magnitude can be produced to render this type of wing tailoring of practical interest.

  18. Effectiveness of culturally tailored diabetes interventions for Asian immigrants to the United States: a systematic review.

    PubMed

    Joo, Jee Young

    2014-01-01

    The purpose of this systematic review is to evaluate the effectiveness of tailoring community-based diabetes intervention to Asian immigrant cultures. The Cochrane processes and Preferred Reporting Items for Systematic Reviews and Meta-Analyses recommendations guided this systematic review. PubMed, the Cumulative Index to Nursing and Allied Health Literature, Ovid, and PsycINFO were searched for analyses and syntheses of primary research published since 2000 that described interventions tailored for the cultures of Asian immigrants with diabetes. This search yielded a total of 9 articles published from 2005 to 2013. The Amsterdam-Maastricht Consensus List for Quality Assessment was used to assess the quality of the studies. Retrieved studies' populations were foreign-born adults >50 years of age with type 2 diabetes. The review revealed that culturally tailored diabetes programs are effective at improving patients' objectively measured clinical outcomes, in particular A1C levels, and psychobehavioral outcomes. Patients were also highly satisfied with bilingual health care providers and bilingual educational programs. There is strong evidence of the effectiveness of tailoring diabetes interventions to Asian immigrant populations' cultures. Further studies, including longitudinal studies and studies with rigorous research designs that subclassify Asian immigrants, are needed to encourage the implementation of culturally tailored diabetes intervention for this ethnic minority. © 2014 The Author(s).

  19. The United States Naval Observatory (USNO) - Naval Oceanography Portal

    Science.gov Websites

    section Advanced Search... Sections Home Time Earth Orientation Astronomy Meteorology Oceanography Ice You Orientation Precise Time James M. Gilliss Library News, Tours & Events About Us Info The United States positions and motion of celestial bodies, motions of the Earth, and precise time. USNO provides tailored

  20. Reducing Alcohol Use During Pregnancy Via Health Counseling by Midwives and Internet-Based Computer-Tailored Feedback: A Cluster Randomized Trial

    PubMed Central

    Hoving, Ciska; Eijmael, Kim; Candel, Math JJM; van Dalen, Wim; De Vries, Hein

    2014-01-01

    Background Effective interventions are needed to reduce neurobehavioral impairments in children due to maternal alcohol use during pregnancy. Currently, health-counseling interventions have shown inconsistent results to reduce prenatal alcohol use. Thus, more research using health counseling is needed to gain more knowledge about the effectiveness of this type of intervention on reducing alcohol use during pregnancy. An alternative and promising strategy is computer tailoring. However, to date, no study has shown the effectiveness of this intervention mode. Objective The aim was to test the effectiveness of health counseling and computer tailoring on stopping and reducing maternal alcohol use during pregnancy in a Dutch sample of pregnant women using alcohol. Methods A total of 60 Dutch midwifery practices, randomly assigned to 1 of 3 conditions, recruited 135 health counseling, 116 computer tailoring, and 142 usual care respondents from February to September 2011. Health-counseling respondents received counseling from their midwife according to a health-counseling protocol, which consisted of 7 steps addressed in 3 feedback sessions. Computer-tailoring respondents received usual care from their midwife and 3 computer-tailored feedback letters via the Internet. Usual care respondents received routine alcohol care from their midwife. After 3 and 6 months, we assessed the effect of the interventions on alcohol use. Results Multilevel multiple logistic regression analyses showed that computer-tailoring respondents stopped using alcohol more often compared to usual care respondents 6 months after baseline (53/68, 78% vs 51/93, 55%; P=.04). Multilevel multiple linear regression analyses showed that computer-tailoring respondents (mean 0.35, SD 0.31 units per week) with average (P=.007) or lower (P<.001) alcohol use before pregnancy or with average (P=.03) or lower (P=.002) social support more strongly reduced their alcohol use 6 months after baseline compared to usual care respondents (mean 0.48, SD 0.54 units per week). Six months after baseline, 72% (62/86) of the health-counseling respondents had stopped using alcohol. This 17% difference with the usual care group was not significant. Conclusions This is the first study showing that computer tailoring can be effective to reduce alcohol use during pregnancy; health counseling did not effectively reduce alcohol use. Future researchers developing a health-counseling intervention to reduce alcohol use during pregnancy are recommended to invest more in recruitment of pregnant women and implementation by health care providers. Because pregnant women are reluctant to disclose their alcohol use to health professionals and computer tailoring preserves a person’s anonymity, this effective computer-tailoring intervention is recommended as an attractive intervention for pregnant women using alcohol. Trial Registration Dutch Trial Register NTR 2058; http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=2058 (Archived by WebCite at http://www.webcitation.org/6NpT1oHol) PMID:25486675

  1. Getting evidence-based pressure ulcer prevention into practice: a multi-faceted unit-tailored intervention in a hospital setting.

    PubMed

    Sving, Eva; Högman, Marieann; Mamhidir, Anna-Greta; Gunningberg, Lena

    2016-10-01

    The aim of the study was to evaluate whether a multi-faceted, unit-tailored intervention using evidenced-based pressure ulcer prevention affects (i) the performance of pressure ulcer prevention, (ii) the prevalence of pressure ulcers and (iii) knowledge and attitudes concerning pressure ulcer prevention among registered and assistant nurses. A quasi-experimental, clustered pre- and post-test design was used. Five units at a hospital setting were included. The intervention was based on the PARIHS framework and included a multi-professional team, training and repeated quality measurements. An established methodology was used to evaluate the prevalence and prevention of pressure ulcers. Nurses' knowledge and attitudes were evaluated using a validated questionnaire. A total of 506 patients were included, of whom 105 patients had a risk to develop pressure ulcer. More patients were provided pressure ulcer prevention care (P = 0·001) and more prevention care was given to each patient (P = 0·021) after the intervention. Corresponding results were shown in the group of patients assessed as being at risk for developing pressure ulcers. Nurses' knowledge about pressure ulcer prevention increased (P < 0·001). Positive attitudes towards pressure ulcer prevention remained high between pre- and post-test surveys. This multi-faceted unit-tailored intervention affected pressure ulcer prevention. Facilitation and repeated quality measurement together with constructed feedback of results seemed to be the most important factor for pressure ulcer prevention. © 2014 The Authors. International Wound Journal © 2014 Medicalhelplines.com Inc and John Wiley & Sons Ltd.

  2. Triple tailored nonlinear dispersion of dressed four- and six-wave mixing

    NASA Astrophysics Data System (ADS)

    Sun, Yanyong; Wang, Zhiguo; Zhang, Zhaoyang; Gu, Bingling; Wang, Kun; Yang, Gaoguo; Zhang, Yanpeng

    2018-06-01

    We investigate the spectral signals and spatial images of a probe transmission signal, four-wave mixing (FWM), and six-wave mixing (SWM) under double dressing effects in an inverted Y-type system. Especially, we get the triple tailored nonlinear dispersion (about 60 MHz) of the dressed FWM and SWM through the interaction between electromagnetically induced transparency (EIT) windows and the Kerr nonlinearity. Moreover, SWM and dressed FWM with narrow linewidth are obtained through the tailoring of the three EIT windows, which is much narrower than the EIT. In addition, we first elaborate the modulation effect from the self-Kerr coefficient of FWM on the spot. We also investigate the spatial characteristics (defocusing, shifting, and splitting) of FWM and SWM induced by tailored self-Kerr and cross-Kerr effects among the relative fields. Such spatial shifting, splitting induced by the tailored nonlinear dispersion can be used for a higher contrast and high speed switch as well as a high resolution router.

  3. Floquet Engineering of Optical Solenoids and Quantized Charge Pumping along Tailored Paths in Two-Dimensional Chern Insulators

    NASA Astrophysics Data System (ADS)

    Wang, Botao; Ünal, F. Nur; Eckardt, André

    2018-06-01

    The insertion of a local magnetic flux, as the one created by a thin solenoid, plays an important role in gedanken experiments of quantum Hall physics. By combining Floquet engineering of artificial magnetic fields with the ability of single-site addressing in quantum gas microscopes, we propose a scheme for the realization of such local solenoid-type magnetic fields in optical lattices. We show that it can be employed to manipulate and probe elementary excitations of a topological Chern insulator. This includes quantized adiabatic charge pumping along tailored paths inside the bulk, as well as the controlled population of edge modes.

  4. Tailored edge-ray concentrators as ideal second stages for Fresnel reflectors.

    PubMed

    Gordon, J M; Ries, H

    1993-05-01

    For both linear and point-focus Fresnel reflectors, we present a new type of ideal nonimaging secondary concentrator, the tailored edge-ray concentrator, that can closely approach the thermodynamic limit of concentration. For large rim-angle heliostat fields, practical-sized secondaries with shapes that should be relatively easy to fabricate can achieve concentrations substantially above those of compound parabolic concentrators. This superiority stems from designing so as to accommodate the particular flux from the heliostat field. The edge-ray principle used for generating the new secondary dictates a heliostat tracking strategy that is different from the conventional one but is equally easy to implement.

  5. Carrier-envelope-phase control of asymmetries in the multiphoton ionization of xenon atoms by ultrashort bichromatic fields

    NASA Astrophysics Data System (ADS)

    Kerbstadt, S.; Pengel, D.; Englert, L.; Bayer, T.; Wollenhaupt, M.

    2018-06-01

    We report on bichromatic multiphoton ionization of xenon atoms (Xe) to demonstrate carrier-envelope-phase (CEP) control of lateral asymmetries in the photoelectron momentum distribution. In the experiments, we employ a 4 f polarization pulse shaper to sculpture bichromatic fields with commensurable center frequencies ω1:ω2=7 :8 from an over-octave-spanning CEP-stable white light supercontinuum by spectral amplitude and phase modulation. The bichromatic fields are spectrally tailored to induce controlled interferences of 7- vs 8-photon quantum pathways in the 5 P3 /2 ionization continuum of Xe. The CEP sensitivity of the asymmetric final-state wave function arises from coherent superposition of continuum states with opposite parity. Our results demonstrate that shaper-generated bichromatic fields with tailored center frequency ratio are a suitable tool to localize CEP-sensitive asymmetries in a specific photoelectron kinetic-energy window.

  6. Advanced Technology Training System on Motor-Operated Valves

    NASA Technical Reports Server (NTRS)

    Wiederholt, Bradley J.; Widjaja, T. Kiki; Yasutake, Joseph Y.; Isoda, Hachiro

    1993-01-01

    This paper describes how features from the field of Intelligent Tutoring Systems are applied to the Motor-Operated Valve (MOV) Advanced Technology Training System (ATTS). The MOV ATTS is a training system developed at Galaxy Scientific Corporation for the Central Research Institute of Electric Power Industry in Japan and the Electric Power Research Institute in the United States. The MOV ATTS combines traditional computer-based training approaches with system simulation, integrated expert systems, and student and expert modeling. The primary goal of the MOV ATTS is to reduce human errors that occur during MOV overhaul and repair. The MOV ATTS addresses this goal by providing basic operational information of the MOV, simulating MOV operation, providing troubleshooting practice of MOV failures, and tailoring this training to the needs of each individual student. The MOV ATTS integrates multiple expert models (functional and procedural) to provide advice and feedback to students. The integration also provides expert model validation support to developers. Student modeling is supported by two separate student models: one model registers and updates the student's current knowledge of basic MOV information, while another model logs the student's actions and errors during troubleshooting exercises. These two models are used to provide tailored feedback to the student during the MOV course.

  7. The application of tailor-made force fields and molecular dynamics for NMR crystallography: a case study of free base cocaine

    PubMed Central

    Neumann, Marcus A.

    2017-01-01

    Motional averaging has been proven to be significant in predicting the chemical shifts in ab initio solid-state NMR calculations, and the applicability of motional averaging with molecular dynamics has been shown to depend on the accuracy of the molecular mechanical force field. The performance of a fully automatically generated tailor-made force field (TMFF) for the dynamic aspects of NMR crystallography is evaluated and compared with existing benchmarks, including static dispersion-corrected density functional theory calculations and the COMPASS force field. The crystal structure of free base cocaine is used as an example. The results reveal that, even though the TMFF outperforms the COMPASS force field for representing the energies and conformations of predicted structures, it does not give significant improvement in the accuracy of NMR calculations. Further studies should direct more attention to anisotropic chemical shifts and development of the method of solid-state NMR calculations. PMID:28250956

  8. Comprehensive overview of computer-based health information tailoring: a scoping review protocol.

    PubMed

    Ghalibaf, Azadeh Kamel; Nazari, Elham; Gholian-Aval, Mahdi; Tabesh, Hamed; Tara, Mahmood

    2017-12-27

    Tailoring health information to the needs of individuals has become an important part of modern health communications. Tailoring has been addressed by researchers from different disciplines leading to the emergence of a wide range of approaches, making the newcomers confused. In order to address this, a comprehensive overview of the field with the indications of research gaps, tendencies and trends will be helpful. As a result, a systematic protocol was outlined to conduct a scoping review within the field of computer-based health information tailoring. This protocol is based on the York's five-stage framework outlined by Arksey and O'Malley. A field-specific structure was defined as a basis for undertaking each stage. The structure comprised three main aspects: system design , information communication and evaluation . Five leading databases were searched: PubMed, Scopus, Science Direct, EBSCO and IEEE and a broad search strategy was used with less strict inclusion criteria to cover the breadth of evidence. Theoretical frameworks were used to develop the data extraction form and a rigorous approach was introduced to identify the categories from data. Several explanatory-descriptive methods were considered to analyse the data, from which some were proposed to be employed for the first time in scoping studies. This study investigates the breadth and depth of existing literature on computer-tailoring and as a secondary analysis, does not require ethics approval. We anticipate that the results will identify research gaps and novel ideas for future studies and provide direction to combine methods from different disciplines. The research findings will be submitted for publication to relevant peer-reviewed journals and conferences targeting health promotion and patient education. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  9. 31 CFR 542.526 - Exportation of services related to conferences in the United States or third countries authorized.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... authorized. (a) The exportation, reexportation, sale, or supply of services from the United States or by a U... from the prohibitions of this part, the exportation, reexportation, sale, or supply of services...), is authorized, provided that the conference or other similar event is not tailored in whole or in...

  10. Spanish-Language Consumer Health Information Technology Interventions: A Systematic Review.

    PubMed

    Chaet, Alexis V; Morshedi, Bijan; Wells, Kristen J; Barnes, Laura E; Valdez, Rupa

    2016-08-10

    As consumer health information technology (IT) becomes more thoroughly integrated into patient care, it is critical that these tools are appropriate for the diverse patient populations whom they are intended to serve. Cultural differences associated with ethnicity are one aspect of diversity that may play a role in user-technology interactions. Our aim was to evaluate the current scope of consumer health IT interventions targeted to the US Spanish-speaking Latino population and to characterize these interventions in terms of technological attributes, health domains, cultural tailoring, and evaluation metrics. A narrative synthesis was conducted of existing Spanish-language consumer health IT interventions indexed within health and computer science databases. Database searches were limited to English-language articles published between January 1990 and September 2015. Studies were included if they detailed an assessment of a patient-centered electronic technology intervention targeting health within the US Spanish-speaking Latino population. Included studies were required to have a majority Latino population sample. The following were extracted from articles: first author's last name, publication year, population characteristics, journal domain, health domain, technology platform and functionality, available languages of intervention, US region, cultural tailoring, intervention delivery location, study design, and evaluation metrics. We included 42 studies in the review. Most of the studies were published between 2009 and 2015 and had a majority percentage of female study participants. The mean age of participants ranged from 15 to 68. Interventions most commonly focused on urban population centers and within the western region of the United States. Of articles specifying a technology domain, computer was found to be most common; however, a fairly even distribution across all technologies was noted. Cancer, diabetes, and child, infant, or maternal health were the most common health domains targeted by consumer health IT interventions. More than half of the interventions were culturally tailored. The most frequently used evaluation metric was behavior/attitude change, followed by usability and knowledge retention. This study characterizes the existing body of research exploring consumer health IT interventions for the US Spanish-speaking Latino population. In doing so, it reveals three primary needs within the field. First, while the increase in studies targeting the Latino population in the last decade is a promising advancement, future research is needed that focuses on Latino subpopulations previously overlooked. Second, preliminary steps have been taken to culturally tailor consumer health IT interventions for the US Spanish-speaking Latino population; however, focus must expand beyond intervention content. Finally, the field should work to promote long-term evaluation of technology efficacy, moving beyond intermediary measures toward measures of health outcomes.

  11. Effectiveness of web-based tailored smoking cessation advice reports (iQuit): a randomized trial.

    PubMed

    Mason, Dan; Gilbert, Hazel; Sutton, Stephen

    2012-12-01

    To determine whether web-based tailored cessation advice, based on social cognitive theory and the perspectives on change model, was more effective in aiding a quit attempt than broadly similar web-based advice that was not tailored. Participants were allocated randomly to one of two groups, to receive either a cessation advice report and progress report that were tailored to individual-level characteristics or a cessation advice report that presented standardized (non-tailored) content. Tailoring was based on smoking-related beliefs, personal characteristics and smoking patterns, self-efficacy and outcome expectations. Participant enrolment and baseline assessments were conducted remotely online via the study website, with the advice reports presented by the same website. Participants (n = 1758) were visitors to the QUIT website who were based in the United Kingdom, aged 18 years or over and who smoked cigarettes or hand-rolled tobacco. Follow-up assessments were made at 6 months by telephone interview. The primary outcome measure was self-reported 3 months prolonged abstinence, and secondary outcomes were 1 month prolonged abstinence, 7-day and 24-hour point prevalence abstinence. The intervention group did not differ from the control group on the primary outcome (9.1% versus 9.3%; odds ratio = 1.02 95% confidence interval 0.73-1.42) or on any of the secondary outcomes. Intervention participants gave more positive evaluations of the materials than control participants. A web-based intervention that tailored content according to smoking-related beliefs, personal characteristics and smoking patterns, self-efficacy and outcome expectations, was not more effective than web-based materials presenting broadly similar non-tailored information. © 2012 The Authors, Addiction © 2012 Society for the Study of Addiction.

  12. Domain engineering of the metastable domains in the 4f-uniaxial-ferromagnet CeRu2Ga2B

    NASA Astrophysics Data System (ADS)

    Wulferding, D.; Kim, H.; Yang, I.; Jeong, J.; Barros, K.; Kato, Y.; Martin, I.; Ayala-Valenzuela, O. E.; Lee, M.; Choi, H. C.; Ronning, F.; Civale, L.; Baumbach, R. E.; Bauer, E. D.; Thompson, J. D.; Movshovich, R.; Kim, Jeehoon

    2017-04-01

    In search of novel, improved materials for magnetic data storage and spintronic devices, compounds that allow a tailoring of magnetic domain shapes and sizes are essential. Good candidates are materials with intrinsic anisotropies or competing interactions, as they are prone to host various domain phases that can be easily and precisely selected by external tuning parameters such as temperature and magnetic field. Here, we utilize vector magnetic fields to visualize directly the magnetic anisotropy in the uniaxial ferromagnet CeRu2Ga2B. We demonstrate a feasible control both globally and locally of domain shapes and sizes by the external field as well as a smooth transition from single stripe to bubble domains, which opens the door to future applications based on magnetic domain tailoring.

  13. Domain engineering of the metastable domains in the 4f-uniaxial-ferromagnet CeRu 2Ga 2B

    DOE PAGES

    Wulferding, Dirk; Kim, Hoon; Yang, Ilkyu; ...

    2017-04-10

    In search of novel, improved materials for magnetic data storage and spintronic devices, compounds that allow a tailoring of magnetic domain shapes and sizes are essential. Good candidates are materials with intrinsic anisotropies or competing interactions, as they are prone to host various domain phases that can be easily and precisely selected by external tuning parameters such as temperature and magnetic field. Here, we utilize vector magnetic fields to visualize directly the magnetic anisotropy in the uniaxial ferromagnet CeRu 2Ga 2B. We demonstrate a feasible control both globally and locally of domain shapes and sizes by the external field asmore » well as a smooth transition from single stripe to bubble domains, which opens the door to future applications based on magnetic domain tailoring.« less

  14. Tailoring superelasticity of soft magnetic materials

    NASA Astrophysics Data System (ADS)

    Cremer, Peet; Löwen, Hartmut; Menzel, Andreas M.

    2015-10-01

    Embedding magnetic colloidal particles in an elastic polymer matrix leads to smart soft materials that can reversibly be addressed from outside by external magnetic fields. We discover a pronounced nonlinear superelastic stress-strain behavior of such materials using numerical simulations. This behavior results from a combination of two stress-induced mechanisms: a detachment mechanism of embedded particle aggregates and a reorientation mechanism of magnetic moments. The superelastic regime can be reversibly tuned or even be switched on and off by external magnetic fields and thus be tailored during operation. Similarities to the superelastic behavior of shape-memory alloys suggest analogous applications, with the additional benefit of reversible switchability and a higher biocompatibility of soft materials.

  15. Tailored Surfaces/Assemblies for Molecular Plasmonics and Plasmonic Molecular Electronics.

    PubMed

    Lacroix, Jean-Christophe; Martin, Pascal; Lacaze, Pierre-Camille

    2017-06-12

    Molecular plasmonics uses and explores molecule-plasmon interactions on metal nanostructures for spectroscopic, nanophotonic, and nanoelectronic devices. This review focuses on tailored surfaces/assemblies for molecular plasmonics and describes active molecular plasmonic devices in which functional molecules and polymers change their structural, electrical, and/or optical properties in response to external stimuli and that can dynamically tune the plasmonic properties. We also explore an emerging research field combining molecular plasmonics and molecular electronics.

  16. Conservatism implications of shock test tailoring for multiple design environments

    NASA Technical Reports Server (NTRS)

    Baca, Thomas J.; Bell, R. Glenn; Robbins, Susan A.

    1987-01-01

    A method for analyzing shock conservation in test specifications that have been tailored to qualify a structure for multiple design environments is discussed. Shock test conservation is qualified for shock response spectra, shock intensity spectra and ranked peak acceleration data in terms of an Index of Conservation (IOC) and an Overtest Factor (OTF). The multi-environment conservation analysis addresses the issue of both absolute and average conservation. The method is demonstrated in a case where four laboratory tests have been specified to qualify a component which must survive seven different field environments. Final judgment of the tailored test specification is shown to require an understanding of the predominant failure modes of the test item.

  17. LPWA using supersonic gas jet with tailored density profile

    NASA Astrophysics Data System (ADS)

    Kononenko, O.; Bohlen, S.; Dale, J.; D'Arcy, R.; Dinter, M.; Erbe, J. H.; Indorf, G.; di Lucchio, L.; Goldberg, L.; Gruse, J. N.; Karstensen, S.; Libov, V.; Ludwig, K.; Martinez de La Ossa, A.; Marutzky, F.; Niroula, A.; Osterhoff, J.; Quast, M.; Schaper, L.; Schwinkendorf, J.-P.; Streeter, M.; Tauscher, G.; Weichert, S.; Palmer, C.; Horbatiuk, Taras

    2016-10-01

    Laser driven plasma wakefield accelerators have been explored as a potential compact, reproducible source of relativistic electron bunches, utilising an electric field of many GV/m. Control over injection of electrons into the wakefield is of crucial importance in producing stable, mono-energetic electron bunches. Density tailoring of the target, to control the acceleration process, can also be used to improve the quality of the bunch. By using gas jets to provide tailored targets it is possible to provide good access for plasma diagnostics while also producing sharp density gradients for density down-ramp injection. OpenFOAM hydrodynamic simulations were used to investigate the possibility of producing tailored density targets in a supersonic gas jet. Particle-in-cell simulations of the resulting density profiles modelled the effect of the tailored density on the properties of the accelerated electron bunch. Here, we present the simulation results together with preliminary experimental measurements of electron and x-ray properties from LPWA experiments using gas jet targets and a 25 TW, 25 fs Ti:Sa laser system at DESY.

  18. 31 CFR 560.554 - Importation and exportation of services related to conferences in the United States or third...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... dealing in such services and the exportation, reexportation, sale, or supply of services from the United... in paragraph (c) of this section, the exportation, reexportation, sale, or supply of services... similar event is not tailored in whole or in part to or for Iran or persons who are ordinarily resident in...

  19. 31 CFR 560.554 - Importation and exportation of services related to conferences in the United States or third...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... dealing in such services and the exportation, reexportation, sale, or supply of services from the United... in paragraph (c) of this section, the exportation, reexportation, sale, or supply of services... similar event is not tailored in whole or in part to or for Iran or persons who are ordinarily resident in...

  20. Disparities in Consumption of Sugar-Sweetened and Other Beverages by Race/Ethnicity and Obesity Status among United States Schoolchildren

    ERIC Educational Resources Information Center

    Dodd, Allison Hedley; Briefel, Ronette; Cabili, Charlotte; Wilson, Ander; Crepinsek, Mary Kay

    2013-01-01

    Objective: Identify disparities by race/ethnicity and obesity status in the consumption of sugar-sweetened beverages (SSBs) and other beverages among United States schoolchildren to help tailor interventions to reduce childhood obesity. Design: Secondary data analysis using beverage intake data from 24-hour dietary recalls and measured height and…

  1. Artes y Humanidades/Economia del Hogar. Libro del Profesor. (Arts & Humanities/Homemaking. Teacher's Guide). B1. CHOICE (Challenging Options in Career Education).

    ERIC Educational Resources Information Center

    Mid-Hudson Migrant Education Center, New Paltz, NY.

    Written in Spanish, the guide comprises the kindergarten level unit of a career education curriculum designed for migrant students. The unit focuses on 11 jobs encompassed by two occupational clusters, arts/humanities and homemaking: teacher, artist, musician, dancer, actor, puppeteer, tailor, janitor, housekeeper, waiter, and child care worker.…

  2. Integrating Partner Nations into Coalition Operations

    DTIC Science & Technology

    2006-01-01

    of United Nations (UN) Security Council Resolu- tion 1529, Chile , Canada, France, and the United States established a multinational force...of restabi- lization. Chile continues to deploy forces as a member of the UN Stabilization Force Haiti (MINUSTAH), led by Brazil and comprised...supporting a tailored exercise and theater security cooperation program that has encouraged partners such as Chile , Brazil, and El Salvador to develop

  3. Microprocessor-based interface for oceanography

    NASA Technical Reports Server (NTRS)

    Hansen, G. R.

    1979-01-01

    Ocean floor imaging system incorporates five identical microprocessor-based interface units each assigned to specific sonar instrument to simplify system. Central control module based on same microprocessor eliminates need for custom tailoring hardware interfaces for each instrument.

  4. Using knowledge of agricultural practices to enhance through-the-season interpretation of Landsat data

    NASA Technical Reports Server (NTRS)

    Malila, W. A.; Pestre, C. R.

    1984-01-01

    Landsat data contain features that can be interpreted to produce information about crops, in support of crop estimation procedures. This paper considers ways in which detailed knowledge of agricultural practices and events might increase and improve the utilization of Landsat data in both the predictive and observational or measurement components of such procedures. Landsat observables related to agricultural practices and events throughout the cropping season are listed. Agricultural fields are identified as the preferred observational units for incorporating refined agricultural understanding, such as crop rotation patterns, into machine procedures. Uses of Landsat data from both prior seasons and the current season are considered, as is use of predictive models of crop appearance. The investigation of knowledge engineering systems tailored to through-the-season estimation problems is recommended for long range development.

  5. Directly tailoring photon-electron coupling for sensitive photoconductance

    NASA Astrophysics Data System (ADS)

    Huang, Zhiming; Zhou, Wei; Huang, Jingguo; Wu, Jing; Gao, Yanqing; Qu, Yue; Chu, Junhao

    2016-03-01

    The coupling between photons and electrons is at the heart of many fundamental phenomena in nature. Despite tremendous advances in controlling electrons by photons in engineered energy-band systems, control over their coupling is still widely lacking. Here we demonstrate an unprecedented ability to couple photon-electron interactions in real space, in which the incident electromagnetic wave directly tailors energy bands of solid to generate carriers for sensitive photoconductance. By spatially coherent manipulation of metal-wrapped material system through anti-symmetric electric field of the irradiated electromagnetic wave, electrons in the metals are injected and accumulated in the induced potential well (EIW) produced in the solid. Respective positive and negative electric conductances are easily observed in n-type and p-type semiconductors into which electrons flow down from the two metallic sides under light irradiation. The photoconductivity is further confirmed by sweeping the injected electrons out of the semiconductor before recombination applied by sufficiently strong electric fields. Our work opens up new perspectives for tailoring energy bands of solids and is especially relevant to develop high effective photon detection, spin injection, and energy harvesting in optoelectronics and electronics.

  6. Electrodeless electrohydrodynamic drop-on-demand encapsulation of drugs into porous polymer films for fabrication of personalized dosage units.

    PubMed

    Elele, Ezinwa; Shen, Yueyang; Susarla, Ramana; Khusid, Boris; Keyvan, Golshid; Michniak-Kohn, Bozena

    2012-07-01

    Noncontact drop-on-demand (DOD) dosing is a promising strategy for manufacturing of personalized dosage units. However, current DOD methods developed for printing chemically and thermally stable, low-viscosity inks are of limited use for pharmaceuticals due to fundamentally different functional requirements. To overcome their deficiency, we developed a novel electrohydrodynamic (EHD) DOD (Appl, Phys, Lett. 97, 233501, 2010) that operates on fluids of up to 30 Pa·s in viscosity over a wide range of droplet sizes and provides a precise control over the droplet volume. We now evaluate the EHD DOD as a method for fabrication of dosage units by printing drug solutions on porous polymer films prepared by freeze-drying. Experiments were carried out on ibuprofen and griseofulvin, as model poorly water-soluble drugs, polyethylene glycol 400, as a drug carrier, and hydroxypropyl methylcellulose films. The similarities between drug release profiles from different dosage units were assessed by model-independent difference, f(1) , and similarity, f(2) , factors. The results presented show that EHD DOD offers a powerful tool for the evolving field of small-scale pharmaceutical technologies for tailoring medicines to individual patient's needs by printing a vast array of predefined amounts of therapeutics arranged in a specific pattern on a porous film. Copyright © 2012 Wiley Periodicals, Inc.

  7. Enhanced magnetocaloric effect tuning efficiency in Ni-Mn-Sn alloy ribbons

    NASA Astrophysics Data System (ADS)

    Quintana-Nedelcos, A.; Sánchez Llamazares, J. L.; Daniel-Perez, G.

    2017-11-01

    The present work was undertaken to investigate the effect of microstructure on the magnetic entropy change of Ni50Mn37Sn13 ribbon alloys. Unchanged sample composition and cell parameter of austenite allowed us to study strictly the correlation between the average grain size and the total magnetic field induced entropy change (ΔST). We found that a size-dependent martensitic transformation tuning results in a wide temperature range tailoring (>40 K) of the magnetic entropy change with a reasonably small variation on the peak value of the total field induced entropy change. The peak values varied from 6.0 J kg-1 K-1 to 7.7 J kg-1 K-1 for applied fields up to 2 T. Different tuning efficiencies obtained by diverse MCE tailoring approaches are compared to highlight the advantages of the herein proposed mechanism.

  8. Increasing Consumer Engagement by Tailoring a Public Reporting Website on the Quality of Diabetes Care: A Qualitative Study

    PubMed Central

    Bednarz, Lauren; Nordby, Peter A; Fink, Jennifer; Greenlee, Robert T; Bolt, Daniel; Magnan, Elizabeth M

    2016-01-01

    Background The majority of health care utilization decisions in the United States are made by persons with multiple chronic conditions. Existing public reports of health system quality do not distinguish care for these persons and are often not used by the consumers they aim to reach. Objective Our goal was to determine if tailoring quality reports to persons with diabetes mellitus and co-occurring chronic conditions would increase user engagement with a website that publicly reports the quality of diabetes care. Methods We adapted an existing consumer-focused public reporting website using adult learning theory to display diabetes quality reports tailored to the user’s chronic condition profile. We conducted in-depth cognitive interviews with 20 individuals who either had diabetes and/or cared for someone with diabetes to assess the website. Interviews were audiotaped and transcribed, then analyzed using thematic content analysis. Results Three themes emerged that suggested increased engagement from tailoring the site to a user’s chronic conditions: ability to interact, relevance, and feeling empowered to act. Conclusions We conclude that tailoring can be used to improve public reporting sites for individuals with chronic conditions, ultimately allowing consumers to make more informed health care decisions. PMID:28003173

  9. Problem posing and cultural tailoring: developing an HIV/AIDS health literacy toolkit with the African American community.

    PubMed

    Rikard, R V; Thompson, Maxine S; Head, Rachel; McNeil, Carlotta; White, Caressa

    2012-09-01

    The rate of HIV infection among African Americans is disproportionately higher than for other racial groups in the United States. Previous research suggests that low level of health literacy (HL) is an underlying factor to explain racial disparities in the prevalence and incidence of HIV/AIDS. The present research describes a community and university project to develop a culturally tailored HIV/AIDS HL toolkit in the African American community. Paulo Freire's pedagogical philosophy and problem-posing methodology served as the guiding framework throughout the development process. Developing the HIV/AIDS HL toolkit occurred in a two-stage process. In Stage 1, a nonprofit organization and research team established a collaborative partnership to develop a culturally tailored HIV/AIDS HL toolkit. In Stage 2, African American community members participated in focus groups conducted as Freirian cultural circles to further refine the HIV/AIDS HL toolkit. In both stages, problem posing engaged participants' knowledge, experiences, and concerns to evaluate a working draft toolkit. The discussion and implications highlight how Freire's pedagogical philosophy and methodology enhances the development of culturally tailored health information.

  10. Shape-tailored polymer colloids on the road to become structural motifs for hierarchically organized materials.

    PubMed

    Plüisch, Claudia Simone; Wittemann, Alexander

    2013-12-01

    Anisometric polymer colloids are likely to behave differently when compared with centrosymmetric particles. Their study may not only shine new light on the organization of matter; they may also serve as building units with specific symmetries and complexity to build new materials from them. Polymer colloids of well-defined complex geometries can be obtained by packing a limited number of spherical polymer particles into clusters with defined configurations. Such supracolloidal architectures can be fabricated at larger scales using narrowly dispersed emulsion droplets as templates. Assemblies built from at least two different types of particles as elementary building units open perspectives in selective targeting of colloids with specific properties, aiming for mesoscale building blocks with tailor-made morphologies and multifunctionality. Polymer colloids with defined geometries are also ideal to study shape-dependent properties such as the diffusion of complex particles. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  11. Mental health issues of muslim americans.

    PubMed

    Basit, Abdul; Hamid, Mohammad

    2010-11-01

    The underpinning of all research leading to various schools of thought in the field of psychiatry and psychology is without doubt a product of Western professionals who represent the religio-cultural traditions, historical symbols, and narratives of Western society. Also, the major schools of psychotherapy emerged during an era of individualism and logical positivism reflecting the religious, ethical, and cultural heritage that has shaped the modern Western society. Consequently, the methods and techniques developed in the West may not be always suitable and effective for Muslim Americans. To respond to the growing needs of psychiatric problems encountered by Muslim Americans, many community social service centers have been established in the United States during the past two decades. We now have a growing body of research data suggesting how to tailor our field to the specific needs of this population. We will discuss what kind of emotional and psychiatric problems are most prevalent in Muslim Americans and explain the therapeutic approaches mental health professionals have used and the treatment strategies which have been found effective in the psychosocial rehabilitation of Muslim Americans.

  12. Ultrasensitive detection and characterization of molecules with infrared plasmonic metamaterials

    PubMed Central

    Cheng, Fei; Yang, Xiaodong; Gao, Jie

    2015-01-01

    Infrared vibrational spectroscopy is an effective technique which enables the direct probe of molecular fingerprints, and such detection can be further enhanced by the emerging engineered plasmonic metamaterials. Here we experimentally demonstrate ultrasensitive detection and characterization of polymer molecules based on an asymmetric infrared plasmonic metamaterial, and quantitatively analyze the molecule detection sensitivity and molecule-structure interactions. A sharp, non-radiative Fano resonance supported by the plasmonic metamaterial exhibits strongly enhanced near-field, and the resonance frequency is tailored to match the vibrational fingerprint of the target molecule. By utilizing the near-field nature of the plasmonic excitation, significantly enhanced absorption signal of molecules in the infrared spectroscopy are obtained, enabling ultrasensitive detection of only minute quantities of organic molecules. The enhancement of molecular absorption up to 105 fold is obtained, and sensitive detection of molecules at zeptomole levels (corresponding to a few tens of molecules within a unit cell) is achieved with high signal-to-noise ratio in our experiment. The demonstrated infrared plasmonic metamaterial sensing platform offers great potential for improving the specificity and sensitivity of label-free, biochemical detection. PMID:26388404

  13. Mental Health Issues of Muslim Americans

    PubMed Central

    Basit, Abdul; Hamid, Mohammad

    2010-01-01

    The underpinning of all research leading to various schools of thought in the field of psychiatry and psychology is without doubt a product of Western professionals who represent the religio-cultural traditions, historical symbols, and narratives of Western society. Also, the major schools of psychotherapy emerged during an era of individualism and logical positivism reflecting the religious, ethical, and cultural heritage that has shaped the modern Western society. Consequently, the methods and techniques developed in the West may not be always suitable and effective for Muslim Americans. To respond to the growing needs of psychiatric problems encountered by Muslim Americans, many community social service centers have been established in the United States during the past two decades. We now have a growing body of research data suggesting how to tailor our field to the specific needs of this population. We will discuss what kind of emotional and psychiatric problems are most prevalent in Muslim Americans and explain the therapeutic approaches mental health professionals have used and the treatment strategies which have been found effective in the psychosocial rehabilitation of Muslim Americans. PMID:23864761

  14. Electric Field-Mediated Processing of Polymers. Appendix 1

    NASA Technical Reports Server (NTRS)

    Wnek, G. E.; Bowlin, G. L.; Haas, T. W.

    2000-01-01

    Significant opportunities exist for the processing of polymers (homopolymers and blends) using electric fields. We suggest that a broad range of properties can be achieved using a relatively small number of polymers, with electric fields providing the ability to tailor properties via the control of shape, morphology, and orientation. Specific attention is given to electrospinning, but we note that electroaerosol formation and field-modulated film casting represent additional processing options.

  15. High effectiveness of tailored flower strips in reducing pests and crop plant damage.

    PubMed

    Tschumi, Matthias; Albrecht, Matthias; Entling, Martin H; Jacot, Katja

    2015-09-07

    Providing key resources to animals may enhance both their biodiversity and the ecosystem services they provide. We examined the performance of annual flower strips targeted at the promotion of natural pest control in winter wheat. Flower strips were experimentally sown along 10 winter wheat fields across a gradient of landscape complexity (i.e. proportion non-crop area within 750 m around focal fields) and compared with 15 fields with wheat control strips. We found strong reductions in cereal leaf beetle(CLB) density (larvae: 40%; adults of the second generation: 53%) and plant damage caused by CLB (61%) in fields with flower strips compared with control fields. Natural enemies of CLB were strongly increased in flower strips and in part also in adjacent wheat fields. Flower strip effects on natural enemies, pests and crop damage were largely independent of landscape complexity(8-75% non-crop area). Our study demonstrates a high effectiveness of annual flower strips in promoting pest control, reducing CLB pest levels below the economic threshold. Hence, the studied flower strip offers a viable alternative to insecticides. This highlights the high potential of tailored agri-environment schemes to contribute to ecological intensification and may encourage more farmers to adopt such schemes.

  16. Tunable mega-ampere electron current propagation in solids by dynamic control of lattice melt

    DOE PAGES

    MacLellan, D.  A.; Carroll, D.  C.; Gray, R.  J.; ...

    2014-10-31

    The influence of lattice-melt-induced resistivity gradients on the transport of mega-ampere currents of fast electrons in solids is investigated numerically and experimentally using laser-accelerated protons to induce isochoric heating. Tailoring the heating profile enables the resistive magnetic fields which strongly influence the current propagation to be manipulated. This tunable laser-driven process enables important fast electron beam properties, including the beam divergence, profile, and symmetry to be actively tailored, and without recourse to complex target manufacture.

  17. Tailoring the energy distribution and loss of 2D plasmons

    DOE PAGES

    Lin, Xiao; Rivera, Nicholas; Lopez, Josue J.; ...

    2016-10-25

    Here, the ability to tailor the energy distribution of plasmons at the nanoscale has many applications in nanophotonics, such as designing plasmon lasers, spasers, and quantum emitters. To this end, we analytically study the energy distribution and the proper field quantization of 2D plasmons with specific examples for graphene plasmons. We find that the portion of the plasmon energy contained inside graphene (energy confinement factor) can exceed 50%, despite graphene being infinitely thin. In fact, this very high energy confinement can make it challenging to tailor the energy distribution of graphene plasmons just by modifying the surrounding dielectric environment ormore » the geometry, such as changing the separation distance between two coupled graphene layers. However, by adopting concepts of parity-time symmetry breaking, we show that tuning the loss in one of the two coupled graphene layers can simultaneously tailor the energy confinement factor and propagation characteristics, causing the phenomenon of loss-induced plasmonic transparency.« less

  18. Flavin-catalyzed redox tailoring reactions in natural product biosynthesis.

    PubMed

    Teufel, Robin

    2017-10-15

    Natural products are distinct and often highly complex organic molecules that constitute not only an important drug source, but have also pushed the field of organic chemistry by providing intricate targets for total synthesis. How the astonishing structural diversity of natural products is enzymatically generated in biosynthetic pathways remains a challenging research area, which requires detailed and sophisticated approaches to elucidate the underlying catalytic mechanisms. Commonly, the diversification of precursor molecules into distinct natural products relies on the action of pathway-specific tailoring enzymes that catalyze, e.g., acylations, glycosylations, or redox reactions. This review highlights a selection of tailoring enzymes that employ riboflavin (vitamin B2)-derived cofactors (FAD and FMN) to facilitate unusual redox catalysis and steer the formation of complex natural product pharmacophores. Remarkably, several such recently reported flavin-dependent tailoring enzymes expand the classical paradigms of flavin biochemistry leading, e.g., to the discovery of the flavin-N5-oxide - a novel flavin redox state and oxygenating species. Copyright © 2017 Elsevier Inc. All rights reserved.

  19. Using computer technology for HIV prevention among African-Americans: development of a tailored information program for safer sex (TIPSS)

    PubMed Central

    Noar, Seth M.; Webb, Elizabeth M.; Van Stee, Stephanie K.; Redding, Colleen A.; Feist-Price, Sonja; Crosby, Richard; Troutman, Adewale

    2011-01-01

    New prevention options are urgently needed for African-Americans in the United States given the disproportionate impact of HIV/AIDS on this group. This combined with recent evidence supporting the efficacy of computer technology-based interventions in HIV prevention led our research group to pursue the development of a computer-delivered individually tailored intervention for heterosexually active African-Americans—the tailored information program for safer sex (TIPSS). In the current article, we discuss the development of the TIPSS program, including (i) the targeted population and behavior, (ii) theoretical basis for the intervention, (iii) design of the intervention, (iv) formative research, (v) technical development and testing and (vi) intervention delivery and ongoing randomized controlled trial. Given the many advantages of computer-based interventions, including low-cost delivery once developed, they offer much promise for the future of HIV prevention among African-Americans and other at-risk groups. PMID:21257676

  20. Cardiac MRI in mice at 9.4 Tesla with a transmit-receive surface coil and a cardiac-tailored intensity-correction algorithm.

    PubMed

    Sosnovik, David E; Dai, Guangping; Nahrendorf, Matthias; Rosen, Bruce R; Seethamraju, Ravi

    2007-08-01

    To evaluate the use of a transmit-receive surface (TRS) coil and a cardiac-tailored intensity-correction algorithm for cardiac MRI in mice at 9.4 Tesla (9.4T). Fast low-angle shot (FLASH) cines, with and without delays alternating with nutations for tailored excitation (DANTE) tagging, were acquired in 13 mice. An intensity-correction algorithm was developed to compensate for the sensitivity profile of the surface coil, and was tailored to account for the unique distribution of noise and flow artifacts in cardiac MR images. Image quality was extremely high and allowed fine structures such as trabeculations, valve cusps, and coronary arteries to be clearly visualized. The tag lines created with the surface coil were also sharp and clearly visible. Application of the intensity-correction algorithm improved signal intensity, tissue contrast, and image quality even further. Importantly, the cardiac-tailored properties of the correction algorithm prevented noise and flow artifacts from being significantly amplified. The feasibility and value of cardiac MRI in mice with a TRS coil has been demonstrated. In addition, a cardiac-tailored intensity-correction algorithm has been developed and shown to improve image quality even further. The use of these techniques could produce significant potential benefits over a broad range of scanners, coil configurations, and field strengths. (c) 2007 Wiley-Liss, Inc.

  1. Spanish-Language Consumer Health Information Technology Interventions: A Systematic Review

    PubMed Central

    Chaet, Alexis V; Morshedi, Bijan; Wells, Kristen J; Barnes, Laura E

    2016-01-01

    Background As consumer health information technology (IT) becomes more thoroughly integrated into patient care, it is critical that these tools are appropriate for the diverse patient populations whom they are intended to serve. Cultural differences associated with ethnicity are one aspect of diversity that may play a role in user-technology interactions. Objective Our aim was to evaluate the current scope of consumer health IT interventions targeted to the US Spanish-speaking Latino population and to characterize these interventions in terms of technological attributes, health domains, cultural tailoring, and evaluation metrics. Methods A narrative synthesis was conducted of existing Spanish-language consumer health IT interventions indexed within health and computer science databases. Database searches were limited to English-language articles published between January 1990 and September 2015. Studies were included if they detailed an assessment of a patient-centered electronic technology intervention targeting health within the US Spanish-speaking Latino population. Included studies were required to have a majority Latino population sample. The following were extracted from articles: first author’s last name, publication year, population characteristics, journal domain, health domain, technology platform and functionality, available languages of intervention, US region, cultural tailoring, intervention delivery location, study design, and evaluation metrics. Results We included 42 studies in the review. Most of the studies were published between 2009 and 2015 and had a majority percentage of female study participants. The mean age of participants ranged from 15 to 68. Interventions most commonly focused on urban population centers and within the western region of the United States. Of articles specifying a technology domain, computer was found to be most common; however, a fairly even distribution across all technologies was noted. Cancer, diabetes, and child, infant, or maternal health were the most common health domains targeted by consumer health IT interventions. More than half of the interventions were culturally tailored. The most frequently used evaluation metric was behavior/attitude change, followed by usability and knowledge retention. Conclusions This study characterizes the existing body of research exploring consumer health IT interventions for the US Spanish-speaking Latino population. In doing so, it reveals three primary needs within the field. First, while the increase in studies targeting the Latino population in the last decade is a promising advancement, future research is needed that focuses on Latino subpopulations previously overlooked. Second, preliminary steps have been taken to culturally tailor consumer health IT interventions for the US Spanish-speaking Latino population; however, focus must expand beyond intervention content. Finally, the field should work to promote long-term evaluation of technology efficacy, moving beyond intermediary measures toward measures of health outcomes. PMID:27511437

  2. Project-Based Management Development: "The Volvo Story."

    ERIC Educational Resources Information Center

    Branch, John; Smith, Bryan

    1992-01-01

    A modular group project-based approach to management development was implemented by Volvo Concessionaires (United Kingdom) in partnership with training consultants. Ingredients of its success included top-level commitment, investment in diagnosis and tailoring, and use of company-specific case studies. (SK)

  3. DMD-based programmable wide field spectrograph for Earth observation

    NASA Astrophysics Data System (ADS)

    Zamkotsian, Frédéric; Lanzoni, Patrick; Liotard, Arnaud; Viard, Thierry; Costes, Vincent; Hébert, Philippe-Jean

    2015-03-01

    In Earth Observation, Universe Observation and Planet Exploration, scientific return could be optimized in future missions using MOEMS devices. In Earth Observation, we propose an innovative reconfigurable instrument, a programmable wide-field spectrograph where both the FOV and the spectrum could be tailored thanks to a 2D micromirror array (MMA). For a linear 1D field of view (FOV), the principle is to use a MMA to select the wavelengths by acting on intensity. This component is placed in the focal plane of a first grating. On the MMA surface, the spatial dimension is along one side of the device and for each spatial point, its spectrum is displayed along the perpendicular direction: each spatial and spectral feature of the 1D FOV is then fully adjustable dynamically and/or programmable. A second stage with an identical grating recomposes the beam after wavelengths selection, leading to an output tailored 1D image. A mock-up has been designed, fabricated and tested. The micromirror array is the largest DMD in 2048 x 1080 mirrors format, with a pitch of 13.68μm. A synthetic linear FOV is generated and typical images have been recorded o at the output focal plane of the instrument. By tailoring the DMD, we could modify successfully each pixel of the input image: for example, it is possible to remove bright objects or, for each spatial pixel, modify the spectral signature. The very promising results obtained on the mock-up of the programmable wide-field spectrograph reveal the efficiency of this new instrument concept for Earth Observation.

  4. Increasing Consumer Engagement by Tailoring a Public Reporting Website on the Quality of Diabetes Care: A Qualitative Study.

    PubMed

    Smith, Maureen A; Bednarz, Lauren; Nordby, Peter A; Fink, Jennifer; Greenlee, Robert T; Bolt, Daniel; Magnan, Elizabeth M

    2016-12-21

    The majority of health care utilization decisions in the United States are made by persons with multiple chronic conditions. Existing public reports of health system quality do not distinguish care for these persons and are often not used by the consumers they aim to reach. Our goal was to determine if tailoring quality reports to persons with diabetes mellitus and co-occurring chronic conditions would increase user engagement with a website that publicly reports the quality of diabetes care. We adapted an existing consumer-focused public reporting website using adult learning theory to display diabetes quality reports tailored to the user's chronic condition profile. We conducted in-depth cognitive interviews with 20 individuals who either had diabetes and/or cared for someone with diabetes to assess the website. Interviews were audiotaped and transcribed, then analyzed using thematic content analysis. Three themes emerged that suggested increased engagement from tailoring the site to a user's chronic conditions: ability to interact, relevance, and feeling empowered to act. We conclude that tailoring can be used to improve public reporting sites for individuals with chronic conditions, ultimately allowing consumers to make more informed health care decisions. ©Maureen A Smith, Lauren Bednarz, Peter A Nordby, Jennifer Fink, Robert T Greenlee, Daniel Bolt, Elizabeth M Magnan. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 21.12.2016.

  5. Mascons, GRACE, and Time-variable Gravity

    NASA Technical Reports Server (NTRS)

    Lemoine, F.; Lutchke, S.; Rowlands, D.; Klosko, S.; Chinn, D.; Boy, J. P.

    2006-01-01

    The GRACE mission has been in orbit now for three years and now regularly produces snapshots of the Earth s gravity field on a monthly basis. The convenient standard approach has been to perform global solutions in spherical harmonics. Alternative local representations of mass variations using mascons show great promise and offer advantages in terms of computational efficiency, minimization of problems due to aliasing, and increased temporal resolution. In this paper, we discuss the results of processing the GRACE KBRR data from March 2003 through August 2005 to produce solutions for GRACE mass variations over mid-latitude and equatorial regions, such as South America, India and the United States, and over the polar regions (Antarctica and Greenland), with a focus on the methodology. We describe in particular mascon solutions developed on regular 4 degree x 4 degree grids, and those tailored specifically to drainage basins over these regions.

  6. Medical Applications of Synchrotron Radiation

    DOE R&D Accomplishments Database

    Thomlinson, W.

    1991-10-01

    Ever since the first diagnostic x-ray was done in the United States on February 3, 1896, the application of ionizing radiation to the field of medicine has become increasingly important. Both in clinical medicine and basic research the use of x-rays for diagnostic imaging and radiotherapy is now widespread. Radiography, angiography, CAT and PETT scanning, mammography, and nuclear medicine are all examples of technologies developed to image the human anatomy. In therapeutic applications, both external and internal sources of radiation are applied to the battle against cancer. The development of dedicated synchrotron radiation sources has allowed exciting advances to take place in many of these applications. The new sources provide tunable, high-intensity monochromatic beams over a wide range of energies which can be tailored to specific programmatic needs. This paper surveys those areas of medical research in which synchrotron radiation facilities are actively involved.

  7. Using Student Competition Field Trips to Increase Teaching and Learning Effectiveness

    ERIC Educational Resources Information Center

    Galbraith, John M.

    2012-01-01

    Teaching and learning effectiveness may be enhanced in small-class settings where teachers can tailor materials and methods to individuals. Preparing students ahead of time for a week-long field trip to a new area that involves student-centered learning and a competition to promote student engagement should offer educational advantages. This…

  8. Near-field plasmonic beam engineering with complex amplitude modulation based on metasurface

    NASA Astrophysics Data System (ADS)

    Song, Xu; Huang, Lingling; Sun, Lin; Zhang, Xiaomeng; Zhao, Ruizhe; Li, Xiaowei; Wang, Jia; Bai, Benfeng; Wang, Yongtian

    2018-02-01

    Metasurfaces have recently intrigued extensive interest due to their ability to locally manipulate electromagnetic waves, which provide great feasibility for tailoring both propagation waves and surface plasmon polaritons (SPPs). Manipulation of SPPs with arbitrary complex fields is an important issue in integrated nanophotonics due to their capability of guiding waves with subwavelength footprints. Here, an approach with metasurfaces composed of nanoaperture arrays is proposed and experimentally demonstrated which can effectively manipulate the complex amplitude of SPPs in the near-field regime. Tailoring the azimuthal angles of individual nanoapertures and simultaneously tuning their geometric parameters, the phase and amplitude are controlled based on the Pancharatnam-Berry phases and their individual transmission coefficients. For the verification of the concept, Airy plasmons and axisymmetric Airy-SPPs are generated. The results of numerical simulations and near-field imaging are consistent with each other. Besides the rigorous simulations, we applied a 2D dipole analysis for additional analysis. This strategy of complex amplitude manipulation with metasurfaces can be used for potential applications in plasmonic beam shaping, integrated optoelectronic systems, and surface wave holography.

  9. Tailoring plasmonic nanoparticles and fractal patterns

    NASA Astrophysics Data System (ADS)

    Rosa, Lorenzo; Juodkazis, Saulius

    2011-12-01

    We studied new three-dimensional tailoring of nano-particles by ion-beam and electron-beam lithographies, aiming for features and nano-gaps down to 10 nm size. Electron-beam patterning is demonstrated for 2D fabrication in combination with plasmonic metal deposition and lift-off, with full control of spectral features of plasmonic nano-particles and patterns on dielectric substrates. We present wide-angle bow-tie rounded nano-antennas whose plasmonic resonances achieve strong field enhancement at engineered wavelength range, and show how the addition of fractal patterns defined by standard electron beam lithography achieve light field enhancement from visible to far-IR spectral range and scalable up towards THz band. Field enhancement is evaluated by FDTD modeling on full-3D simulation domains using complex material models, showing the modeling method capabilities and the effect of staircase approximations on field enhancement and resonance conditions, especially at metal corners, where a minimum rounding radius of 2 nm is resolved and a five-fold reduction of spurious ringing at sharp corners is obtained by the use of conformal meshing.

  10. Multipole and field uniformity tailoring of a 750 MHz rf dipole

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Delayen, Jean R.; Castillo, Alejandro

    2014-12-01

    In recent years great interest has been shown in developing rf structures for beam separation, correction of geometrical degradation on luminosity, and diagnostic applications in both lepton and hadron machines. The rf dipole being a very promising one among all of them. The rf dipole has been tested and proven to have attractive properties that include high shunt impedance, low and balance surface fields, absence of lower order modes and far-spaced higher order modes that simplify their damping scheme. As well as to be a compact and versatile design in a considerable range of frequencies, its fairly simple geometry dependencymore » is suitable both for fabrication and surface treatment. The rf dipole geometry can also be optimized for lowering multipacting risk and multipole tailoring to meet machine specific field uniformity tolerances. In the present work a survey of field uniformities, and multipole contents for a set of 750 MHz rf dipole designs is presented as both a qualitative and quantitative analysis of the inherent flexibility of the structure and its limitations.« less

  11. Controlling electron quantum paths for generation of circularly polarized high-order harmonics by H2+ subject to tailored (ω , 2 ω ) counter-rotating laser fields

    NASA Astrophysics Data System (ADS)

    Heslar, John; Telnov, Dmitry A.; Chu, Shih-I.

    2018-04-01

    Recently, studies of high-order harmonics (HHG) from atoms driven by bichromatic counter-rotating circularly polarized laser fields as a source of coherent circularly polarized extreme ultraviolet (XUV) and soft-x-ray beams in a tabletop-scale setup have received considerable attention. Here, we demonstrate the ability to control the electron recollisions giving three returns per one cycle of the fundamental frequency ω by using tailored bichromatic (ω , 2 ω ) counter-rotating circularly polarized laser fields with a molecular target. The full control of the electronic pathway is first analyzed by a classical trajectory analysis and then extended to a detailed quantum study of H2+ molecules in bichromatic (ω , 2 ω ) counter-rotating circularly polarized laser fields. The radiation spectrum contains doublets of left- and right-circularly polarized harmonics in the XUV ranges. We study in detail the below-, near-, and above-threshold harmonic regions and describe how excited-state resonances alter the ellipticity and phase of the generated harmonic peaks.

  12. Oromucosal multilayer films for tailor-made, controlled drug delivery.

    PubMed

    Lindert, Sandra; Breitkreutz, Jörg

    2017-11-01

    The oral mucosa has recently become increasingly important as an alternative administration route for tailor-made, controlled drug delivery. Oromucosal multilayer films, assigned to the monograph oromucosal preparations in the Ph.Eur. may be a promising dosage form to overcome the requirements related to this drug delivery site. Areas covered: We provide an overview of multilayer films as drug delivery tools, and discuss manufacturing processes and characterization methods. We focus on the suitability of characterization methods for particular requirements of multilayer films. A classification was performed covering indication areas and APIs incorporated in multilayer film systems for oromucosal use in order to provide a summary of data published in this field. Expert opinion: The shift in drug development to high molecular weight drugs will influence the field of pharmaceutical development and delivery technologies. For a high number of indication areas, such as hormonal disorders, cardiovascular diseases or local treatment of infections, the flexible layer design of oromucosal multilayer films provides a promising option for tailor-made, controlled delivery of APIs to or through defined surfaces in the oral cavity. However, there is a lack of discriminating or standardized testing methods to assess the quality of multilayer films in a reliable way.

  13. Future Autonomous Robotic Systems in the Pacific Theater

    DTIC Science & Technology

    2015-05-06

    areas to inform the friendly units behind of what potential threats lurk within. Once secure supply routes are established, driverless vehicles can...developing new ARS, from driverless vehicles to handheld medical devices that dispense personal diagnoses, tailored to that individual’s medical

  14. Tailor-made Molecular Cobalt Catalyst System for the Selective Transformation of Carbon Dioxide to Dialkoxymethane Ethers.

    PubMed

    Schieweck, Benjamin G; Klankermayer, Jürgen

    2017-08-28

    Herein a non-precious transition-metal catalyst system for the selective synthesis of dialkoxymethane ethers from carbon dioxide and molecular hydrogen is presented. The development of a tailored catalyst system based on cobalt salts in combination with selected Triphos ligands and acidic co-catalysts enabled a synthetic pathway, avoiding the oxidation of methanol to attain the formaldehyde level of the central CH 2 unit. This unprecedented productivity based on the molecular cobalt catalyst is the first example of a non-precious transition-metal system for this transformation utilizing renewable carbon dioxide sources. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  15. Tailoring nanoscale morphology of polymer: Fullerene blends using electrostatic field

    DOE PAGES

    Elshobaki, Moneim; Gebhardt, Ryan; Carr, John; ...

    2016-12-05

    In this paper, to tailor the nanoscale phase separation in polymer/fullerene blends, we study the effect of electrostatic field (E-field) on the solidification of poly(3-hexylthiophene-2, 5-diyl) (P3HT):[6,6]-phenyl-C61-butyric acid methyl ester (PC 60BM) bulk heterojunction (BHJ). In addition to untreated sample (control); wet P3HT:PC 60BM thin films were exposed to E-field of Van de Graaff (VDG) generator at three different directions – horizontal (H), tilted (T) and vertical (V) – relative to the plane of the substrate. Surface and bulk characterizations of field-treated BHJs affirm that fullerene molecules can easily penetrate the spaghetti-like P3HT and move up and down following themore » E-field. E-field treatment yields thin films with large P3HT- and PCBM-rich domains acting as continuous pathways for efficient charge separation, transport, and collection. We improve; (1) the hole mobility values up to 19.4 × 10 -4 ± 1.6 × 10 -4 cm 2 V -1 s -1 (117% higher than the control), and (2) power conversion efficient (PCE) of conventional and inverted OPVs recording 2.58 ± 0.02% and 4.1 ± 0.4%. This E-field approach can serve as a new morphology-tuning technique, which is generally applicable to other polymer-fullerene systems.« less

  16. The perceived quality of interprofessional teamwork in an intensive care unit: A single centre intervention study.

    PubMed

    Van den Bulcke, Bo; Vyt, Andre; Vanheule, Stijn; Hoste, Eric; Decruyenaere, Johan; Benoit, Dominique

    2016-05-01

    This article describes a study that evaluated the quality of teamwork in a surgical intensive care unit and assessed whether teamwork could be improved significantly through a tailor-made intervention. The quality of teamwork prior to and after the intervention was assessed using the Interprofessional Practice and Education Quality Scales (IPEQS) using the PROSE online diagnostics and documenting system, which assesses three domains of teamwork: organisational factors, care processes, and team members' attitudes and beliefs. Furthermore, team members evaluated strengths and weaknesses of the teamwork through open-ended questions. Information gathered by means of the open questions was used to design a tailor-made 12-week intervention consisting of (1) optimising the existing weekly interdisciplinary meetings with collaborative decision-making and clear communication of goal-oriented actions, including the psychosocial aspects of care; and (2) organising and supporting the effective exchange of information over time between all professions involved. It was found that the intervention had a significant impact on organisational factors and care processes related to interprofessional teamwork for the total group and within all subgroups, despite baseline differences between the subgroups in interprofessional teamwork. In conclusion, teamwork, and more particularly the organisational aspects of interprofessional collaboration and processes of care, can be improved by a tailor-made intervention that takes into account the professional needs of healthcare workers.

  17. High effectiveness of tailored flower strips in reducing pests and crop plant damage

    PubMed Central

    Tschumi, Matthias; Albrecht, Matthias; Entling, Martin H.; Jacot, Katja

    2015-01-01

    Providing key resources to animals may enhance both their biodiversity and the ecosystem services they provide. We examined the performance of annual flower strips targeted at the promotion of natural pest control in winter wheat. Flower strips were experimentally sown along 10 winter wheat fields across a gradient of landscape complexity (i.e. proportion non-crop area within 750 m around focal fields) and compared with 15 fields with wheat control strips. We found strong reductions in cereal leaf beetle (CLB) density (larvae: 40%; adults of the second generation: 53%) and plant damage caused by CLB (61%) in fields with flower strips compared with control fields. Natural enemies of CLB were strongly increased in flower strips and in part also in adjacent wheat fields. Flower strip effects on natural enemies, pests and crop damage were largely independent of landscape complexity (8–75% non-crop area). Our study demonstrates a high effectiveness of annual flower strips in promoting pest control, reducing CLB pest levels below the economic threshold. Hence, the studied flower strip offers a viable alternative to insecticides. This highlights the high potential of tailored agri-environment schemes to contribute to ecological intensification and may encourage more farmers to adopt such schemes. PMID:26311668

  18. What’s in a Surname? Physique, Aptitude, and Sports Type Comparisons between Tailors and Smiths

    PubMed Central

    Voracek, Martin; Rieder, Stephan; Stieger, Stefan; Swami, Viren

    2015-01-01

    Combined heredity of surnames and physique, coupled with past marriage patterns and trade-specific physical aptitude and selection factors, may have led to differential assortment of bodily characteristics among present-day men with specific trade-reflecting surnames (Tailor vs. Smith). Two studies reported here were partially consistent with this genetic-social hypothesis, first proposed by Bäumler (1980). Study 1 (N = 224) indicated significantly higher self-rated physical aptitude for prototypically strength-related activities (professions, sports, hobbies) in a random sample of Smiths. The counterpart effect (higher aptitude for dexterity-related activities among Tailors) was directionally correct, but not significant, and Tailor-Smith differences in basic physique variables were nil. Study 2 examined two large total-population-of-interest datasets (Austria/Germany combined, and UK: N = 7001 and 20532) of men’s national high-score lists for track-and-field events requiring different physiques. In both datasets, proportions of Smiths significantly increased from light-stature over medium-stature to heavy-stature sports categories. The predicted counterpart effect (decreasing prevalences of Tailors along these categories) was not supported. Related prior findings, the viability of possible alternative interpretations of the evidence (differential positive selection for trades and occupations, differential endogamy and assortative mating patterns, implicit egotism effects), and directions for further inquiry are discussed in conclusion. PMID:26161803

  19. What's in a Surname? Physique, Aptitude, and Sports Type Comparisons between Tailors and Smiths.

    PubMed

    Voracek, Martin; Rieder, Stephan; Stieger, Stefan; Swami, Viren

    2015-01-01

    Combined heredity of surnames and physique, coupled with past marriage patterns and trade-specific physical aptitude and selection factors, may have led to differential assortment of bodily characteristics among present-day men with specific trade-reflecting surnames (Tailor vs. Smith). Two studies reported here were partially consistent with this genetic-social hypothesis, first proposed by Bäumler (1980). Study 1 (N = 224) indicated significantly higher self-rated physical aptitude for prototypically strength-related activities (professions, sports, hobbies) in a random sample of Smiths. The counterpart effect (higher aptitude for dexterity-related activities among Tailors) was directionally correct, but not significant, and Tailor-Smith differences in basic physique variables were nil. Study 2 examined two large total-population-of-interest datasets (Austria/Germany combined, and UK: N = 7001 and 20,532) of men's national high-score lists for track-and-field events requiring different physiques. In both datasets, proportions of Smiths significantly increased from light-stature over medium-stature to heavy-stature sports categories. The predicted counterpart effect (decreasing prevalences of Tailors along these categories) was not supported. Related prior findings, the viability of possible alternative interpretations of the evidence (differential positive selection for trades and occupations, differential endogamy and assortative mating patterns, implicit egotism effects), and directions for further inquiry are discussed in conclusion.

  20. A programmable metasurface with dynamic polarization, scattering and focusing control

    NASA Astrophysics Data System (ADS)

    Yang, Huanhuan; Cao, Xiangyu; Yang, Fan; Gao, Jun; Xu, Shenheng; Li, Maokun; Chen, Xibi; Zhao, Yi; Zheng, Yuejun; Li, Sijia

    2016-10-01

    Diverse electromagnetic (EM) responses of a programmable metasurface with a relatively large scale have been investigated, where multiple functionalities are obtained on the same surface. The unit cell in the metasurface is integrated with one PIN diode, and thus a binary coded phase is realized for a single polarization. Exploiting this anisotropic characteristic, reconfigurable polarization conversion is presented first. Then the dynamic scattering performance for two kinds of sources, i.e. a plane wave and a point source, is carefully elaborated. To tailor the scattering properties, genetic algorithm, normally based on binary coding, is coupled with the scattering pattern analysis to optimize the coding matrix. Besides, inverse fast Fourier transform (IFFT) technique is also introduced to expedite the optimization process of a large metasurface. Since the coding control of each unit cell allows a local and direct modulation of EM wave, various EM phenomena including anomalous reflection, diffusion, beam steering and beam forming are successfully demonstrated by both simulations and experiments. It is worthwhile to point out that a real-time switch among these functionalities is also achieved by using a field-programmable gate array (FPGA). All the results suggest that the proposed programmable metasurface has great potentials for future applications.

  1. A programmable metasurface with dynamic polarization, scattering and focusing control

    PubMed Central

    Yang, Huanhuan; Cao, Xiangyu; Yang, Fan; Gao, Jun; Xu, Shenheng; Li, Maokun; Chen, Xibi; Zhao, Yi; Zheng, Yuejun; Li, Sijia

    2016-01-01

    Diverse electromagnetic (EM) responses of a programmable metasurface with a relatively large scale have been investigated, where multiple functionalities are obtained on the same surface. The unit cell in the metasurface is integrated with one PIN diode, and thus a binary coded phase is realized for a single polarization. Exploiting this anisotropic characteristic, reconfigurable polarization conversion is presented first. Then the dynamic scattering performance for two kinds of sources, i.e. a plane wave and a point source, is carefully elaborated. To tailor the scattering properties, genetic algorithm, normally based on binary coding, is coupled with the scattering pattern analysis to optimize the coding matrix. Besides, inverse fast Fourier transform (IFFT) technique is also introduced to expedite the optimization process of a large metasurface. Since the coding control of each unit cell allows a local and direct modulation of EM wave, various EM phenomena including anomalous reflection, diffusion, beam steering and beam forming are successfully demonstrated by both simulations and experiments. It is worthwhile to point out that a real-time switch among these functionalities is also achieved by using a field-programmable gate array (FPGA). All the results suggest that the proposed programmable metasurface has great potentials for future applications. PMID:27774997

  2. A programmable metasurface with dynamic polarization, scattering and focusing control.

    PubMed

    Yang, Huanhuan; Cao, Xiangyu; Yang, Fan; Gao, Jun; Xu, Shenheng; Li, Maokun; Chen, Xibi; Zhao, Yi; Zheng, Yuejun; Li, Sijia

    2016-10-24

    Diverse electromagnetic (EM) responses of a programmable metasurface with a relatively large scale have been investigated, where multiple functionalities are obtained on the same surface. The unit cell in the metasurface is integrated with one PIN diode, and thus a binary coded phase is realized for a single polarization. Exploiting this anisotropic characteristic, reconfigurable polarization conversion is presented first. Then the dynamic scattering performance for two kinds of sources, i.e. a plane wave and a point source, is carefully elaborated. To tailor the scattering properties, genetic algorithm, normally based on binary coding, is coupled with the scattering pattern analysis to optimize the coding matrix. Besides, inverse fast Fourier transform (IFFT) technique is also introduced to expedite the optimization process of a large metasurface. Since the coding control of each unit cell allows a local and direct modulation of EM wave, various EM phenomena including anomalous reflection, diffusion, beam steering and beam forming are successfully demonstrated by both simulations and experiments. It is worthwhile to point out that a real-time switch among these functionalities is also achieved by using a field-programmable gate array (FPGA). All the results suggest that the proposed programmable metasurface has great potentials for future applications.

  3. A Field Experiment Testing the Utility of Regulatory Fit Messages for Promoting Physical Activity.

    PubMed

    Latimer, Amy E; Rivers, Susan E; Rench, Tara A; Katulak, Nicole A; Hicks, Althea; Hodorowski, Julie Keany; Higgins, E Tory; Salovey, Peter

    2008-05-01

    Guided by regulatory focus theory, we examined whether messages tailored to individuals' promotion- or prevention-goal orientation (regulatory focus) elicit positive thoughts and feelings about physical activity and increase participation in physical activity. Inactive participants (N = 206) were assigned randomly to receive either promotion-focused or prevention-focused messages encouraging physical activity. Two weeks after message exposure, we assessed participants' thoughts and feelings about physical activity and physical activity behavior. Tailored messages that fit individuals' regulatory focus led to greater physical activity participation and more positive feelings than non-fit messages, particularly in the promotion-focused condition. Furthermore, positive retrospective feelings about physical activity mediated the effects of the tailored messages on behavior. These findings provide support for regulatory focus theory and direction for enhancing the effectiveness of messages encouraging physical activity and other health behaviors.

  4. Tailored semiconductors for high-harmonic optoelectronics

    NASA Astrophysics Data System (ADS)

    Sivis, Murat; Taucer, Marco; Vampa, Giulio; Johnston, Kyle; Staudte, André; Naumov, Andrei Yu.; Villeneuve, D. M.; Ropers, Claus; Corkum, P. B.

    2017-07-01

    The advent of high-harmonic generation in gases 30 years ago set the foundation for attosecond science and facilitated ultrafast spectroscopy in atoms, molecules, and solids. We explore high-harmonic generation in the solid state by means of nanostructured and ion-implanted semiconductors. We use wavelength-selective microscopic imaging to map enhanced harmonic emission and show that the generation medium and the driving field can be locally tailored in solids by modifying the chemical composition and morphology. This enables the control of high-harmonic technology within precisely engineered solid targets. We demonstrate customized high-harmonic wave fields with wavelengths down to 225 nanometers (ninth-harmonic order of 2-micrometer laser pulses) and present an integrated Fresnel zone plate target in silicon, which leads to diffraction-limited self-focusing of the generated harmonics down to 1-micrometer spot sizes.

  5. Nanoscale tailor-made membranes for precise and rapid molecular sieve separation.

    PubMed

    Wang, Jing; Zhu, Junyong; Zhang, Yatao; Liu, Jindun; Van der Bruggen, Bart

    2017-03-02

    The precise and rapid separation of different molecules from aqueous, organic solutions and gas mixtures is critical to many technologies in the context of resource-saving and sustainable development. The strength of membrane-based technologies is well recognized and they are extensively applied as cost-effective, highly efficient separation techniques. Currently, empirical-based approaches, lacking an accurate nanoscale control, are used to prepare the most advanced membranes. In contrast, nanoscale control renders the membrane molecular specificity (sub-2 nm) necessary for efficient and rapid molecular separation. Therefore, as a growing trend in membrane technology, the field of nanoscale tailor-made membranes is highlighted in this review. An in-depth analysis of the latest advances in tailor-made membranes for precise and rapid molecule sieving is given, along with an outlook to future perspectives of such membranes. Special attention is paid to the established processing strategies, as well as the application of molecular dynamics (MD) simulation in nanoporous membrane design. This review will provide useful guidelines for future research in the development of nanoscale tailor-made membranes with a precise and rapid molecular sieve separation property.

  6. Anti-Mullerian hormone-tailored stimulation protocols improve outcomes whilst reducing adverse effects and costs of IVF.

    PubMed

    Yates, A P; Rustamov, O; Roberts, S A; Lim, H Y N; Pemberton, P W; Smith, A; Nardo, L G

    2011-09-01

    Anti-Müllerian hormone (AMH) is increasingly used to quantify ovarian reserve, but it has not yet realized its full clinical potential in assisted reproduction technology. We investigated the possible benefits of using novel, stratified ovarian hyperstimulation protocols, tailored to individual AMH levels, compared with conventional stimulation. Retrospective data were collected from 769 women (first cycle of IVF, using fresh embryos), in a UK tertiary care unit: 346 women using conventional stimulation protocols; 423 women treated under new AMH-tailored protocols. Embryo transfer rates increased significantly (79-87%: P= 0.002) after the introduction of AMH-tailored stimulation protocols. Pregnancy rate per cycle started and live birth rate also increased significantly compared with conventionally treated women (17.9-27.7%, P= 0.002 and 15.9-23.9%, P = 0.007, respectively). Moreover, in the AMH group, the incidence of the ovarian hyperstimulation syndrome (OHSS) fell significantly (6.9-2.3%, P = 0.002) and failed fertilization fell from 7.8 to 4.5%. The cost of fertility drug treatment fell by 29% per patient and the overall cost of clinical management of OHSS fell by 43% in the AMH group. GnRH antagonist protocols, introduced as part of AMH-tailored treatment, may have contributed to the observed improvements: however, within the AMH-tailored group, the live birth rate was not significantly different between agonist and antagonist-treated groups. Although large, prospective, multicentre studies are indicated, we have clearly demonstrated that individualized, AMH-guided, controlled ovarian hyperstimulation protocols significantly improved positive clinical outcomes, reduced the incidence of complications and reduced the financial burden associated with assisted reproduction.

  7. Tailored Training in Vehicle Maintenance Courses

    DTIC Science & Technology

    2014-07-01

    The use of the MCT was limited to the 91M test class during this research effort. There were no other limitations imposed by unit leaders on the MCT’s... one group size to another. Since previous discussions with unit training managers indicated about 80% of all training was designed to be executed in... designated small training groups of four to five Soldiers, it was decided that individual observers would be assigned to collect data on only one of

  8. The National Military Strategy of the United States of America 2015: The United States Military’s Contribution to National Security

    DTIC Science & Technology

    2015-06-01

    are amplified by shifting demographics. Youth populations are rapidly growing in Africa and the Middle East, regions that face resource shortages...fear in opponents and generate support for their causes. They use improvised explosive devices (IED), suicide vests, and tailored cyber tools to...our security relationship with India and build upon our partnerships with New Zealand, Singapore, Indonesia, Malaysia , Vietnam, and Bangladesh. Such

  9. Unit Specific Crew Rest Strategies: Phase 1 Evaluation of the 1/212th Aviation Battalion during Shiftwork Transitions

    DTIC Science & Technology

    1994-01-01

    but do not provide strategies or specific schedules of crew rest tailored to the- unit’s specific mission demands, environmental conditions, and...and the impact of mission driven work schedules and environmental conditions on crew rest quality. Phase II provides rhythms, sleep/wake cycles...shiftwork schedules , and methods for regulating the body’s biological clock to prevent sleep loss during characteristic mission. This report contains a

  10. Technologies for Developing Predictive Atomistic and Coarse-Grained Force Fields for Ionic Liquid Property Prediction

    DTIC Science & Technology

    2008-07-29

    minimization is performed. It is critical that all other force field parameters (for bonds, angles, charges, and Lennard-Jones interactions) be pre...and tailoring the parameterization accordingly may be critical . For Phase I, the above described procedure was performed manually to obtain dihedral... critical that a reliable approach is available to guide experimental efforts and design. In addition, the automation of force field development will

  11. Tailoring the Electromagnetic Near Field with Patterned Surfaces: Near-Field Plates

    DTIC Science & Technology

    2014-12-10

    single layer processing. 3 Near-field plates can be viewed as metamaterial surfaces ( metasurfaces or metafilms) [20]. They are textured/structured at a...Applied Physics Letters, vol. 103, 041104, July 2013. 3. C. Pfeiffer and A. Grbic, ”Cascaded metasurfaces for complete phase and polarization control...Antennas and Propagation, pp. 1-2, Memphis, TN, July 6-12, 2014. 5. Pfeiffer and A. Grbic, ”Analysis and synthesis of bianisotropic metasurfaces

  12. A brief culturally tailored intervention for Puerto Ricans with type 2 diabetes.

    PubMed

    Osborn, Chandra Y; Amico, K R; Cruz, Noemi; O'Connell, Ann A; Perez-Escamilla, Rafael; Kalichman, Seth C; Wolf, Scott A; Fisher, Jeffrey D

    2010-12-01

    The information-motivation-behavioral skills (IMB) model of health behavior change informed the design of a brief, culturally tailored diabetes self-care intervention for Puerto Ricans with type 2 diabetes. Participants (n = 118) were recruited from an outpatient, primary care clinic at an urban hospital in the northeast United States. ANCOVA models evaluated intervention effects on food label reading, diet adherence, physical activity, and glycemic control (HbA1c). At follow-up, the intervention group was reading food labels and adhering to diet recommendations significantly more than the control group. Although the mean HbA1c values decreased in both groups ( 0.48% vs. 0.27% absolute decrease), only the intervention group showed a significant improvement from baseline to follow-up (p < .008), corroborating improvements in diabetes self-care behaviors. Findings support the use of the IMB model to culturally tailor diabetes interventions and to enhance patients' knowledge, motivation, and behavior skills needed for self-care.

  13. The Preventing Suicide Network: Delivering online tailored resources to those who help others.

    PubMed

    Elfrink, Victoria; Schlachta-Fairchild, Loretta; Szczur, Martha; Chang, Hua Florence; Young-Weeden, Elizabeth; Rocca, Mitra

    2006-01-01

    Concerned over the growing epidemic of death by suicide in the United States, the National Institute of Mental Health of the U.S. National Institutes of Health funded Small Business Innovation Research (SBIR) projects using innovative web-based approaches to provide resources to professionals and the general public about suicide prevention. The Preventing Suicide Network (PSN) was funded (SBIR Contract #N44MH22044) and developed over a three and a half year period (2001-2005) as part of this initiative. The PSN provides intermediaries (those who participate in activities to prevent suicide) with an online community dedicated to timely access to authoritative and problem-specific tailored information.

  14. Integration Process for the Habitat Demonstration Unit

    NASA Technical Reports Server (NTRS)

    Gill, Tracy; Merbitz, Jerad; Kennedy, Kriss; Tri, Terry; Howe, A. Scott

    2010-01-01

    The Habitat Demonstration Unit (HDU) is an experimental exploration habitat technology and architecture test platform designed for analog demonstration activities The HDU project has required a team to integrate a variety of contributions from NASA centers and outside collaborators and poses a challenge in integrating these disparate efforts into a cohesive architecture To complete the development of the HDU from conception in June 2009 to rollout for operations in July 2010, a cohesive integration strategy has been developed to integrate the various systems of HDU and the payloads, such as the Geology Lab, that those systems will support The utilization of interface design standards and uniquely tailored reviews have allowed for an accelerated design process Scheduled activities include early fit-checks and the utilization of a Habitat avionics test bed prior to equipment installation into HDU A coordinated effort to utilize modeling and simulation systems has aided in design and integration concept development Modeling tools have been effective in hardware systems layout, cable routing and length estimation, and human factors analysis Decision processes on the shell development including the assembly sequence and the transportation have been fleshed out early on HDU to maximize the efficiency of both integration and field operations Incremental test operations leading up to an integrated systems test allows for an orderly systems test program The HDU will begin its journey as an emulation of a Pressurized Excursion Module (PEM) for 2010 field testing and then may evolve to a Pressurized Core Module (PCM) for 2011 and later field tests, depending on agency architecture decisions The HDU deployment will vary slightly from current lunar architecture plans to include developmental hardware and software items and additional systems called opportunities for technology demonstration One of the HDU challenges has been designing to be prepared for the integration of presently unanticipated systems Results of the HDU field tests will influence future designs of habitat systems.

  15. The electrostatic fluidic trap: a new approach to the spatial control and manipulation of matter at the nanometer scale (presentation video)

    NASA Astrophysics Data System (ADS)

    Krishnan, Madhavi

    2014-09-01

    I will describe a new technique to trap matter at the nanometer scale in fluids. Rather than apply external fields to the object of interest, our approach relies on spatial tailoring of the interaction between an object and its neighbouring surfaces in order to create spatial potential minima in three dimensions. We demonstrate how the strong and long-ranged electrostatic interaction can be modulated by tailoring substrate geometry to achieve stable spatial trapping of charged objects, as small as single proteins in solution.

  16. Magnetic separations in biotechnology.

    PubMed

    Borlido, L; Azevedo, A M; Roque, A C A; Aires-Barros, M R

    2013-12-01

    Magnetic separations are probably one of the most versatile separation processes in biotechnology as they are able to purify cells, viruses, proteins and nucleic acids directly from crude samples. The fast and gentle process in combination with its easy scale-up and automation provide unique advantages over other separation techniques. In the midst of this process are the magnetic adsorbents tailored for the envisioned target and whose complex synthesis spans over multiple fields of science. In this context, this article reviews both the synthesis and tailoring of magnetic adsorbents for bioseparations as well as their ultimate application. Copyright © 2013 Elsevier Inc. All rights reserved.

  17. Biomolecular structure manipulation using tailored electromagnetic radiation: a proof of concept on a simplified model of the active site of bacterial DNA topoisomerase.

    PubMed

    Jarukanont, Daungruthai; Coimbra, João T S; Bauerhenne, Bernd; Fernandes, Pedro A; Patel, Shekhar; Ramos, Maria J; Garcia, Martin E

    2014-10-21

    We report on the viability of breaking selected bonds in biological systems using tailored electromagnetic radiation. We first demonstrate, by performing large-scale simulations, that pulsed electric fields cannot produce selective bond breaking. Then, we present a theoretical framework for describing selective energy concentration on particular bonds of biomolecules upon application of tailored electromagnetic radiation. The theory is based on the mapping of biomolecules to a set of coupled harmonic oscillators and on optimal control schemes to describe optimization of temporal shape, the phase and polarization of the external radiation. We have applied this theory to demonstrate the possibility of selective bond breaking in the active site of bacterial DNA topoisomerase. For this purpose, we have focused on a model that was built based on a case study. Results are given as a proof of concept.

  18. Defining and Assessing Chinese Syntactic Complexity via TC-Units

    ERIC Educational Resources Information Center

    Yu, Qiaona

    2016-01-01

    The triad dimensions of complexity, accuracy, and fluency (CAF) has been widely used for assessing second language performance and development. Unlike accuracy and fluency, the construct of Chinese syntactic complexity has not been comprehensibly conceptualized or operationalized. Moreover, not tailored to the typological differences such as the…

  19. Public Housing: A Tailored Approach to Energy Retrofits

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    J. Dentz; Conlin, F.; Podorson, D.

    2016-02-23

    The Building America research team Advanced Residential Integrated Energy Solutions Collaborative (ARIES) worked with four public housing authorities (PHAs) to develop packages of energy-efficiency retrofit measures that the PHAs can cost-effectively implement with their own staffs during the normal course of housing operations when units are refurbished between occupancies.

  20. A brief tailored family-centered seat belt intervention for hospitalized trauma patients.

    DOT National Transportation Integrated Search

    2010-11-01

    "Among children 5-19 years, the commonest cause of unintentional injury-related death is : being an occupant/driver in a motor vehicle crash (MVC). In 2006 in the United States, there : were 568,188 injuries among children (0-18) due to MVC. Of these...

  1. Relative Contributions of Geothermal Pumping and Long-Term Earthquake Rate to Seismicity at California Geothermal Fields

    NASA Astrophysics Data System (ADS)

    Weiser, D. A.; Jackson, D. D.

    2015-12-01

    In a tectonically active area, a definitive discrimination between geothermally-induced and tectonic earthquakes is difficult to achieve. We focus our study on California's 11 major geothermal fields: Amedee, Brawley, Casa Diablo, Coso, East Mesa, The Geysers, Heber, Litchfield, Salton Sea, Susanville, and Wendel. The Geysers geothermal field is the world's largest geothermal energy producer. California's Department of Oil Gas and Geothermal Resources provides field-wide monthly injection and production volumes for each of these sites, which allows us to study the relationship between geothermal pumping activities and seismicity. Since many of the geothermal fields began injecting and producing before nearby seismic stations were installed, we use smoothed seismicity since 1932 from the ANSS catalog as a proxy for tectonic earthquake rate. We examine both geothermal pumping and long-term earthquake rate as factors that may control earthquake rate. Rather than focusing only on the largest earthquake, which is essentially a random occurrence in time, we examine how M≥4 earthquake rate density (probability per unit area, time, and magnitude) varies for each field. We estimate relative contributions to the observed earthquake rate of M≥4 from both a long-term earthquake rate (Kagan and Jackson, 2010) and pumping activity. For each geothermal field, respective earthquake catalogs (NCEDC and SCSN) are complete above at least M3 during the test period (which we tailor to each site). We test the hypothesis that the observed earthquake rate at a geothermal site during the test period is a linear combination of the long-term seismicity and pumping rates. We use a grid search to determine the confidence interval of the weighting parameters.

  2. Tailoring of the partial magnonic gap in three-dimensional magnetoferritin-based magnonic crystals

    NASA Astrophysics Data System (ADS)

    Mamica, S.

    2013-07-01

    We investigate theoretically the use of magnetoferritin nanoparticles, self-assembled in the protein crystallization process, as the basis for the realization of 3D magnonic crystals in which the interparticle space is filled with a ferromagnetic material. Using the plane wave method we study the dependence of the width of the partial band gap and its central frequency on the total magnetic moment of the magnetoferritin core and the lattice constant of the magnetoferritin crystal. We show that by adjusting the combination of these two parameters the partial gap can be tailored in a wide frequency range and shifted to sub-terahertz frequencies. Moreover, the difference in the width of the partial gap for spin waves propagating in planes parallel and perpendicular to the external field allows for switching on and off the partial magnonic gap by changing the direction of the applied field.

  3. Polymeric blends for sensor and actuation dual functionality

    NASA Technical Reports Server (NTRS)

    St. Clair, Terry L. (Inventor); Harrison, Joycelyn S. (Inventor); Su, Ji (Inventor); Ounaies, Zoubeida (Inventor)

    2004-01-01

    The invention described herein supplies a new class of electroactive polymeric blend materials which offer both sensing and actuation dual functionality. The blend comprises two components, one component having a sensing capability and the other component having an actuating capability. These components should be co-processable and coexisting in a phase separated blend system. Specifically, the materials are blends of a sensing component selected from the group consisting of ferroelectric, piezoelectric, pyroelectric and photoelectric polymers and an actuating component that responds to an electric field in terms of dimensional change. Said actuating component includes, but is not limited to, electrostrictive graft elastomers, dielectric electroactive elastomers, liquid crystal electroactive elastomers and field responsive polymeric gels. The sensor functionality and actuation functionality are designed by tailoring the relative fraction of the two components. The temperature dependence of the piezoelectric response and the mechanical toughness of the dual functional blends are also tailored by the composition adjustment.

  4. Efficient fabrication of carbon nanotube micro tip arrays by tailoring cross-stacked carbon nanotube sheets.

    PubMed

    Wei, Yang; Liu, Peng; Zhu, Feng; Jiang, Kaili; Li, Qunqing; Fan, Shoushan

    2012-04-11

    Carbon nanotube (CNT) micro tip arrays with hairpin structures on patterned silicon wafers were efficiently fabricated by tailoring the cross-stacked CNT sheet with laser. A blade-like structure was formed at the laser-cut edges of the CNT sheet. CNT field emitters, pulled out from the end of the hairpin by an adhesive tape, can provide 150 μA intrinsic emission currents with low beam noise. The nice field emission is ascribed to the Joule-heating-induced desorption of the emitter surface by the hairpin structure, the high temperature annealing effect, and the surface morphology. The CNT emitters with hairpin structures will greatly promote the applications of CNTs in vacuum electronic devices and hold the promises to be used as the hot tips for thermochemical nanolithography. More CNT-based structures and devices can be fabricated on a large scale by this versatile method. © 2012 American Chemical Society

  5. APPLYING LESSONS LEARNED FROM THE UNITED STATES SPECIAL OPERATIONS COMMAND’S HUMAN PERFORMANCE PROGRAM TO THE UNITED STATES AIR FORCES COMPREHENSIVE AIRMAN FITNESS

    DTIC Science & Technology

    2016-04-01

    implementation, focusing physical training on the mission specific requirements of the individual similar to an athletic sports model, increasing access to...initiative as a mechanism to help maintain the resiliency, health, and welfare of its force.1 As Air Force Instruction (AFI) 90-506 states, the strategy ...implementation of Tactical Athlete Programs, which provide tailored workout plans and nutrition education that prepare service members to meet the physical

  6. Tailoring light-matter coupling in semiconductor and hybrid-plasmonic nanowires

    PubMed Central

    Piccione, Brian; Aspetti, Carlos O.; Cho, Chang-Hee; Agarwal, Ritesh

    2014-01-01

    Understanding interactions between light and matter is central to many fields, providing invaluable insights into the nature of matter. In its own right, a greater understanding of light-matter coupling has allowed for the creation of tailored applications, resulting in a variety of devices such as lasers, switches, sensors, modulators, and detectors. Reduction of optical mode volume is crucial to enhancing light-matter coupling strength, and among solid-state systems, self-assembled semiconductor and hybrid-plasmonic nanowires are amenable to creation of highly-confined optical modes. Following development of unique spectroscopic techniques designed for the nanowire morphology, carefully engineered semiconductor nanowire cavities have recently been tailored to enhance light-matter coupling strength in a manner previously seen in optical microcavities. Much smaller mode volumes in tailored hybrid-plasmonic nanowires have recently allowed for similar breakthroughs, resulting in sub-picosecond excited-state lifetimes and exceptionally high radiative rate enhancement. Here, we review literature on light-matter interactions in semiconductor and hybrid-plasmonic monolithic nanowire optical cavities to highlight recent progress made in tailoring light-matter coupling strengths. Beginning with a discussion of relevant concepts from optical physics, we will discuss how our knowledge of light-matter coupling has evolved with our ability to produce ever-shrinking optical mode volumes, shifting focus from bulk materials to optical microcavities, before moving on to recent results obtained from semiconducting nanowires. PMID:25093385

  7. 3D print of polymer bonded rare-earth magnets, and 3D magnetic field scanning with an end-user 3D printer

    NASA Astrophysics Data System (ADS)

    Huber, C.; Abert, C.; Bruckner, F.; Groenefeld, M.; Muthsam, O.; Schuschnigg, S.; Sirak, K.; Thanhoffer, R.; Teliban, I.; Vogler, C.; Windl, R.; Suess, D.

    2016-10-01

    3D print is a recently developed technique, for single-unit production, and for structures that have been impossible to build previously. The current work presents a method to 3D print polymer bonded isotropic hard magnets with a low-cost, end-user 3D printer. Commercially available isotropic NdFeB powder inside a PA11 matrix is characterized, and prepared for the printing process. An example of a printed magnet with a complex shape that was designed to generate a specific stray field is presented, and compared with finite element simulation solving the macroscopic Maxwell equations. For magnetic characterization, and comparing 3D printed structures with injection molded parts, hysteresis measurements are performed. To measure the stray field outside the magnet, the printer is upgraded to a 3D magnetic flux density measurement system. To skip an elaborate adjusting of the sensor, a simulation is used to calibrate the angles, sensitivity, and the offset of the sensor. With this setup, a measurement resolution of 0.05 mm along the z-axes is achievable. The effectiveness of our calibration method is shown. With our setup, we are able to print polymer bonded magnetic systems with the freedom of having a specific complex shape with locally tailored magnetic properties. The 3D scanning setup is easy to mount, and with our calibration method we are able to get accurate measuring results of the stray field.

  8. Evaluation of End-User Satisfaction Among Employees Participating in a Web-based Health Risk Assessment With Tailored Feedback

    PubMed Central

    Colkesen, Ersen B; Niessen, Maurice AJ; Kraaijenhagen, Roderik A; Essink-Bot, Marie-Louise; Peek, Niels

    2012-01-01

    Background Web technology is increasingly being used to provide individuals with health risk assessments (HRAs) with tailored feedback. End-user satisfaction is an important determinant of the potential impact of HRAs, as this influences program attrition and adherence to behavioral advice. Objective The aim of this study was to evaluate end-user satisfaction with a web-based HRA with tailored feedback applied in worksite settings, using mixed (quantitative and qualitative) methods. Methods Employees of seven companies in the Netherlands participated in a commercial, web-based, HRA with tailored feedback. The HRA consisted of four components: 1) a health and lifestyle assessment questionnaire, 2) a biometric evaluation, 3) a laboratory evaluation, and 4) tailored feedback consisting of a personal health risk profile and lifestyle behavior advice communicated through a web portal. HRA respondents received an evaluation questionnaire after six weeks. Satisfaction with different parts of the HRA was measured on 5-point Likert scales. A free-text field provided the opportunity to make additional comments. Results In total, 2289 employees participated in the HRA program, of which 637 (27.8%) completed the evaluation questionnaire. Quantitative analysis showed that 85.6% of the respondents evaluated the overall HRA positively. The free-text field was filled in by 29.7 % of the respondents (189 out of 637), who made 315 separate remarks. Qualitative evaluation of these data showed that these respondents made critical remarks. Respondents felt restricted by the answer categories of the health and lifestyle assessment questionnaire, which resulted in the feeling that the corresponding feedback could be inadequate. Some respondents perceived the personal risk profile as unnecessarily alarming or suggested providing more explanations, reference values, and a justification of the behavioral advice given. Respondents also requested the opportunity to discuss the feedback with a health professional. Conclusions Most people were satisfied with the web-based HRA with tailored feedback. Sources of dissatisfaction were limited opportunities for providing additional health information outside of the predefined health and lifestyle assessment questionnaire and insufficient transparency on the generation of the feedback. Information regarding the aim and content of the HRA should be clear and accurate to prevent unrealistic expectations among end-users. Involving trusted health professionals in the implementation of web-based HRAs may enhance the use of and confidence in the HRA. PMID:23111097

  9. Evaluation of end-user satisfaction among employees participating in a web-based health risk assessment with tailored feedback.

    PubMed

    Vosbergen, Sandra; Laan, Eva K; Colkesen, Ersen B; Niessen, Maurice A J; Kraaijenhagen, Roderik A; Essink-Bot, Marie-Louise; Peek, Niels

    2012-10-30

    Web technology is increasingly being used to provide individuals with health risk assessments (HRAs) with tailored feedback. End-user satisfaction is an important determinant of the potential impact of HRAs, as this influences program attrition and adherence to behavioral advice. The aim of this study was to evaluate end-user satisfaction with a web-based HRA with tailored feedback applied in worksite settings, using mixed (quantitative and qualitative) methods. Employees of seven companies in the Netherlands participated in a commercial, web-based, HRA with tailored feedback. The HRA consisted of four components: 1) a health and lifestyle assessment questionnaire, 2) a biometric evaluation, 3) a laboratory evaluation, and 4) tailored feedback consisting of a personal health risk profile and lifestyle behavior advice communicated through a web portal. HRA respondents received an evaluation questionnaire after six weeks. Satisfaction with different parts of the HRA was measured on 5-point Likert scales. A free-text field provided the opportunity to make additional comments. In total, 2289 employees participated in the HRA program, of which 637 (27.8%) completed the evaluation questionnaire. Quantitative analysis showed that 85.6% of the respondents evaluated the overall HRA positively. The free-text field was filled in by 29.7 % of the respondents (189 out of 637), who made 315 separate remarks. Qualitative evaluation of these data showed that these respondents made critical remarks. Respondents felt restricted by the answer categories of the health and lifestyle assessment questionnaire, which resulted in the feeling that the corresponding feedback could be inadequate. Some respondents perceived the personal risk profile as unnecessarily alarming or suggested providing more explanations, reference values, and a justification of the behavioral advice given. Respondents also requested the opportunity to discuss the feedback with a health professional. Most people were satisfied with the web-based HRA with tailored feedback. Sources of dissatisfaction were limited opportunities for providing additional health information outside of the predefined health and lifestyle assessment questionnaire and insufficient transparency on the generation of the feedback. Information regarding the aim and content of the HRA should be clear and accurate to prevent unrealistic expectations among end-users. Involving trusted health professionals in the implementation of web-based HRAs may enhance the use of and confidence in the HRA.

  10. Biomedical imaging and therapy with physically and physiologically tailored magnetic nanoparticles

    NASA Astrophysics Data System (ADS)

    Khandhar, Amit Praful

    Magnetic particle imaging (MPI) and magnetic fluid hyperthermia (MFH) are emerging imaging and therapy approaches that have the potential to improve diagnostic safety and disease management of heart disease and cancer - the number 1 and 2 leading causes of deaths in the United States. MPI promises real-time, tomographic and quantitative imaging of superparamagnetic iron oxide nanoparticle (SPION) tracers distributed in vivo, and is targeted to offer a safer angiography alternative for its first clinical application. MFH uses ac-fields to dissipate heat from SPIONs that can be delivered locally to promote hyperthermia therapy (~42°C) in cancer cells. Both technologies use safe radiofrequency magnetic fields to exploit the fundamental magnetic relaxation properties of superparamagnetic iron oxide nanoparticles (SPIONs), which must be tailored for optimal imaging in the case of MPI, and maximum hyperthermia potency in the case of MFH. Furthermore, the magnetic core and shell of SPIONs are both central to the optimization process; the shell, in particular, bridges the translational gap between the optimized core and its safe and effective use in the physiological environment. Unfortunately, existing SPIONs that were originally designed as MRI contrast agents lack the basic physical properties that enable the clinical translation of MPI and MFH. In this work, the core and shell of monodisperse SPIONs were optimized in concert to accomplish two equally important objectives: (1) biocompatibility, and (2) MPI and MFH efficacy of SPIONs in physiological environments. Critically, it was found that the physical and physiological responses of SPIONs are coupled, and impacting one can have consequences on the other. It was shown that the poly(ethylene glycol) (PEG)-based shell when properly optimized reduced protein adsorption to SPION surface and phagocytic uptake in macrophages - both prerequisites for designing long-circulating SPIONs. In MPI, tailoring the surface coating reduced protein adsorption and improved colloidal stability, which were critical in retaining the magnetization relaxation properties of the SPIONs. The improvements in surface coatings enabled the use of larger SPION cores (> 20 nm core diameter), which were used to demonstrate benchmark-imaging performance in some of the world's first MPI scanners at Philips Medical Imaging and University of California, Berkeley. In MFH, it was shown for the first time that optimization of heat loss from SPIONs (W/g) is possible by tailoring the core size and size distribution for the given ac-field conditions. Biodistribution and blood circulation studies in mice showed that SPIONs accumulated primarily in the liver and spleen with minimal renal involvement, and demonstrated gradual clearance. Circulation time was evaluated using the MPI signal detected over time in blood, which offered insight on the relevant circulation time for angiography applications. In comparison with carboxy-dextran coated ResovistRTM SPIONs, the PEG-coated SPIONs developed in this work circulated substantially longer; furthermore, reducing the hydrodynamic diameter showed a 4.5x improvement in blood half-life. The work presented in this thesis demonstrates that the combined effort in optimizing the core and shell properties of SPIONs enhances biocompatibility and efficacy, with the in vivo studies providing critical feedback on the success (or failure) of the optimization process. Future work will entail designing functionalized SPIONs for targeting specific disease sites, which will further enable the molecular level diagnosis and therapy of diseases.

  11. Tailoring the chirality of light emission with spherical Si-based antennas.

    PubMed

    Zambrana-Puyalto, Xavier; Bonod, Nicolas

    2016-05-21

    Chirality of light is of fundamental importance in several enabling technologies with growing applications in life sciences, chemistry and photodetection. Recently, some attention has been focused on chiral quantum emitters. Consequently, optical antennas which are able to tailor the chirality of light emission are needed. Spherical nanoresonators such as colloids are of particular interest to design optical antennas since they can be synthesized at a large scale and they exhibit good optical properties. Here, we show that these colloids can be used to tailor the chirality of a chiral emitter. To this purpose, we derive an analytic formalism to model the interaction between a chiral emitter and a spherical resonator. We then compare the performances of metallic and dielectric spherical antennas to tailor the chirality of light emission. It is seen that, due to their strong electric dipolar response, metallic spherical nanoparticles spoil the chirality of light emission by yielding achiral fields. In contrast, thanks to the combined excitation of electric and magnetic modes, dielectric Si-based particles feature the ability to inhibit or to boost the chirality of light emission. Finally, it is shown that dual modes in dielectric antennas preserve the chirality of light emission.

  12. Improved Operational Readiness through Environmental Stress Screening

    DTIC Science & Technology

    1987-11-01

    Rhoades of Gru-,.:an’s Field Marketing Department, and the cooperation of the ni- merous Air Force logistics centers and operational facilities visited...EQUIPMENT AGE * ENVIRONMENTAL MAINTENANCE EFFECT PROFILES DtATA * TAILORING DEFINTION MET HOD1OLOGY I 1GUIDELINE oi FIELD ESS IMPLEMENTATION GUIDELINW...any mixing or mismatching appeared, the data was eliminated completely. Figure 5 provides the annual historical trends of each case history equipment

  13. Extended parametric gain range in photonic crystal fibers with strongly frequency-dependent field distributions.

    PubMed

    Petersen, Sidsel R; Alkeskjold, Thomas T; Olausson, Christina B; Lægsgaard, Jesper

    2014-08-15

    The parametric gain range of a degenerate four-wave mixing process is determined in the undepleted pump regime. The gain range is considered with and without taking the mode field distributions of the four-wave mixing components into account. It is found that the mode field distributions have to be included to evaluate the parametric gain correctly in dispersion-tailored speciality fibers and that mode profile engineering can provide a way to increase the parametric gain range.

  14. Designing for Users: Online Information Literacy in the Middle East

    ERIC Educational Resources Information Center

    Martin, Janet; Birks, Jane; Hunt, Fiona

    2010-01-01

    Librarians from Zayed University in the United Arab Emirates (UAE) report on an empirical evaluation of the relevance and value of Infoasis (http://www.zu.ac.ae/infoasis), a Web-based information literacy tutorial developed and tailored to the Arab student population of the Emirates. After the successful implementation of this project, questions…

  15. Cluster Dynamics: Laying the Foundation for Tailoring the Design of Cluster ASSE

    DTIC Science & Technology

    2016-02-25

    UNIVERSITY 201 OLD MAIN UNIVERSITY PARK, PA 16802-1505 02/25/2016 Final Report DISTRIBUTION A: Distribution approved for public release. Air Force...5f.  WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) PENNSYLVANIA STATE UNIVERSITY 201 OLD MAIN UNIVERSITY PARK, PA 16802-1505 US 8

  16. Technology to Support Teachers Using Evidence from Student Work to Customize Technology-Enhanced Inquiry Units

    ERIC Educational Resources Information Center

    Matuk, Camillia F.; Linn, Marcia C.; Eylon, Bat-Sheva

    2015-01-01

    Teachers' involvement in curriculum design is essential for sustaining the relevance of technology-enhanced learning materials. Customizing--making small adjustments to tailor given materials to particular situations and settings--is one design activity in which busy teachers can feasibly engage. Research indicates that customizations based…

  17. Supplying Community College Needs in Basic Speech Courses at Florida Junior College at Jacksonville, Florida.

    ERIC Educational Resources Information Center

    Griggs, Dorothy Feldbinder; Shannon, Mary Louise

    At Florida Junior College at Jacksonville, public speaking instructors employ Jerome S. Bruner's four factors of learning--predisposition to learn, structure of knowledge, sequence, and reinforcement--to plan an effective learning program for students with diverse academic backgrounds and goals. Specifically, six learning units, tailored to both…

  18. Virtual Counseling for Students Enrolled in Online Educational Programs

    ERIC Educational Resources Information Center

    Currie, Nikki S.

    2010-01-01

    Virtual schools are increasing in popularity as a method of providing formal education for a growing number of students in the United States. The economy, coupled with technological advances and parental demand for a more personalized, innovative, individually tailored, and high quality education alternative for their children has led to the…

  19. Ada Adoption Handbook: A Program Manager’s Guide, Version 2.0

    DTIC Science & Technology

    1992-10-01

    specifically Ada oriented: "* Compilation order tool: A capability that, when given a set of Ada units, determines the com- pilation order. "* Automatic...July 1992. 146. Knapper. R. J., Linn, C. J.. & Salasin, J. Guidelines for Tailoring DOD-S TD-2167A for SOS Software Development. IDA Paper P- 2018

  20. Student Town Meeting with Vice President Al Gore. Teacher's Guide.

    ERIC Educational Resources Information Center

    Edwards, Amy N.

    This teacher's guide accompanies a videotape of the same name. Vice President Albert Gore, Jr., discusses current issues with students who question Mr. Gore on such topics as the environment, reinventing government, voter participation, crime, and the United States' role in foreign affairs. Gore tailors his answers to the teenage audience as the…

  1. Light-triggered self-assembly of triarylamine-based nanospheres

    NASA Astrophysics Data System (ADS)

    Moulin, Emilie; Niess, Frédéric; Fuks, Gad; Jouault, Nicolas; Buhler, Eric; Giuseppone, Nicolas

    2012-10-01

    Tailored triarylamine units modified with terpyridine ligands were coordinated to Zn2+ ions and characterized as discrete dimeric entities. Interestingly, when these complexes were subsequently irradiated with simple visible light in chloroform, they readily self-assembled into monodisperse spheres with a mean diameter of 160 nm.Tailored triarylamine units modified with terpyridine ligands were coordinated to Zn2+ ions and characterized as discrete dimeric entities. Interestingly, when these complexes were subsequently irradiated with simple visible light in chloroform, they readily self-assembled into monodisperse spheres with a mean diameter of 160 nm. Electronic supplementary information (ESI) available: Synthetic procedures and products' characterization (2-4 and 6-9). 1H NMR titration of compound 6 by Zn(OTf)2 to form complex 7. Kinetic measurements by UV-Vis-NIR spectroscopy. Transmission electron microscopy imaging for complexes 8 and 9. UV-Vis-NIR for an Fe2+ analogue of complex 7. Dynamic light scattering and time autocorrelation function for self-assembly of complexes 7-9. Copies of 1H and 13C NMR spectra for compounds 2-4 and 6. See DOI: 10.1039/c2nr32168h

  2. Improving the quality of primary care by allocating performance-based targets, in a diverse insured population.

    PubMed

    Peled, Ronit; Porath, Avi; Wilf-Miron, Rachel

    2016-11-21

    Primary Care Health organizations, operating under universal coverage and a regulated package of benefits, compete mainly over quality of care. Monitoring, primary care clinical performance, has been repeatedly proven effective in improving the quality of care. In 2004, Maccabi Healthcare Services (MHS), the second largest Israeli HMO, launched its Performance Measurement System (PMS) based on clinical quality indicators. A unique module was built in the PMS to adjust for case mix while tailoring targets to the local units. This article presents the concept and formulas developed to adjust targets to the units' current performance, and analyze change in clinical indicators over a six year period, between sub-population groups. Six process and intermediate outcome indicators, representing screening for breast and colorectal cancer and care for patients with diabetes and cardiovascular disease, were selected and analyzed for change over time (2003-2009) in overall performance, as well as the difference between the lowest and the highest socio-economic ranks (SERs) and Arab and non-Arab members. MHS demonstrated a significant improvement in the selected indicators over the years. Performance of members from low SERs and Arabs improved to a greater extent, as compared to members from high ranks and non-Arabs, respectively. The performance measurement system, with its module for tailoring of units' targets, served as a managerial vehicle for bridging existing gaps by allocating more resources to lower performing units. This concept was proven effective in improving performance while reducing disparities between diverse population groups.

  3. Implementation of multidimensional knowledge translation strategies to improve procedural pain in hospitalized children.

    PubMed

    Stevens, Bonnie J; Yamada, Janet; Promislow, Sara; Stinson, Jennifer; Harrison, Denise; Victor, J Charles

    2014-11-25

    Despite extensive research, institutional policies, and practice guidelines, procedural pain remains undertreated in hospitalized children. Knowledge translation (KT) strategies have been employed to bridge the research to practice gap with varying success. The most effective single or combination of KT strategies has not been found. A multifaceted KT intervention, Evidence-based Practice for Improving Quality (EPIQ), that included tailored KT strategies was effective in improving pain practices and clinical outcomes at the unit level in a prospective comparative cohort study in 32 hospital units (16 EPIQ intervention and 16 Standard Care), in eight pediatric hospitals in Canada. In a study of the 16 EPIQ units (two at each hospital) only, the objectives were to: determine the effectiveness of evidence-based KT strategies implemented to achieve unit aims; describe the KT strategies implemented and their influence on pain assessment and management across unit types; and identify facilitators and barriers to their implementation. Data were collected from each EPIQ intervention unit on targeted pain practices and KT strategies implemented, through chart review and a process evaluation checklist, following four intervention cycles over a 15-month period. Following the completion of the four cycle intervention, 78% of 23 targeted pain practice aims across units were achieved within 80% of the stated aims. A statistically significant improvement was found in the proportion of children receiving pain assessment and management, regardless of pre-determined aims (p < 0.001). The median number of KT strategies implemented was 35 and included reminders, educational outreach and materials, and audit and feedback. Units successful in achieving their aims implemented more KT strategies than units that did not. No specific type of single or combination of KT strategies was more effective in improving pain assessment and management outcomes. Tailoring KT strategies to unit context, support from unit leadership, staff engagement, and dedicated time and resources were identified as facilitating effective implementation of the strategies. Further research is required to better understand implementation outcomes, such as feasibility and fidelity, how context influences the effectiveness of multifaceted KT strategies, and the sustainability of improved pain practices and outcomes over time.

  4. Development of a portable petroleum by-products chemical sensor, phase 1 and 2 report.

    DOT National Transportation Integrated Search

    2006-07-31

    We have proposed to tailor design nanoparticle based chemical sensors for the sensitive, selective and field portable analyses of soil samples for petroleum spill indicating hydrocarbons (such as benzene, toluene, ethyl-benzenes, xylenes, PCBs, trich...

  5. Tailoring the magnetostructural transition and magnetocaloric properties around room temperature: In-doped Ni-Mn-Ga alloys

    NASA Astrophysics Data System (ADS)

    Zhang, Linfang; Wang, Jingmin; Hua, Hui; Jiang, Chengbao; Xu, Huibin

    2014-09-01

    Some off-stoichiometric Ni-Mn-Ga alloys undergo a coupled magnetostructural transition from ferromagnetic martensite to paramagnetic austenite, giving rise to the large magnetocaloric effect. However, the magnetostructural transitions of Ni-Mn-Ga alloys generally take place at temperatures higher than room temperature. Here, we report that by the partial substitution of In for Ga, the paramagnetic austenite phase is well stabilized, and the magnetostructural transition can be tailored around room temperature. Sizable magnetic entropy change and adiabatic temperature change were induced by magnetic field change in the vicinity of the magnetostructural transition of the In-doped Ni-Mn-Ga alloys.

  6. Tailoring Thermal Radiative Properties with Doped-Silicon Nanowires

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang, Zhuomin

    Aligned doped-silicon nanowire (D-SiNW) arrays form a hyperbolic metamaterial in the mid-infrared and have unique thermal radiative properties, such as broadband omnidirectional absorption, low-loss negative refraction, etc. A combined theoretical and experimental investigation will be performed to characterize D-SiNW arrays and other metamaterials for tailoring thermal radiative properties. Near-field thermal radiation between anisotropic materials with hyperbolic dispersions will also be predicted for potential application in energy harvesting. A new kind of anisotropic metamaterial with a hyperbolic dispersion in a broad infrared region has been proposed and demonstrated based on aligned doped-silicon nanowire (D-SiNW) arrays. D-SiNW-based metamaterials have unique thermal radiativemore » properties, such as broadband omnidirectional absorption whose width and location can be tuned by varying the filling ratio and/or doping level. Furthermore, high figure of merit (FOM) can be achieved in a wide spectral region, suggesting that D-SiNW arrays may be used as a negative refraction material with much less loss than other structured materials, such as layered semiconductor materials. We have also shown that D-SiNWs and other nanostructures can significantly enhance near-field thermal radiation. The study of near-field radiative heat transfer between closely spaced objects and the electromagnetic wave interactions with micro/nanostructured materials has become an emerging multidisciplinary field due to its importance in advanced energy systems, manufacturing, local thermal management, and high spatial resolution thermal sensing and mapping. We have performed extensive study on the energy streamlines involving anisotropic metamaterials and the applicability of the effective medium theory for near-field thermal radiation. Graphene as a 2D material has attracted great attention in nanoelectronics, plasmonics, and energy harvesting. We have shown that graphene can be used to tailor the transmittance, reflectance, and absorptance of nanostructured materials. Furthermore, graphene can be used to enhance near-field coupling to increase the phonon tunneling probability. We have performed analysis of near-field thermophotovoltaic devices with backside reflecting mirror and with tungsten gratings. We have predicted a large enhancement of electroluminescent refrigeration at a separation distance down to 10 nm due to near-field thermal radiation effect. A heat flux measurement system is developed to measure the near-field radiation in vacuum. We have fabricated doped Si plates separated by sparsely distributed posts to create a 200-800 nm vacuum gap. Our measurement results demonstrate that 11 times enhancement of near-field thermal radiation between parallel doped-Si plates with a lateral dimension 1 cm by 1 cm.« less

  7. [Identification of capacities in environmental health from environmental authorities in Colombia].

    PubMed

    Agudelo-Calderón, Carlos A; García-Ubaque, Juan C; Robledo-Martínez, Rocío; García-Ubaque, Cesar A; Vaca-Bohórquez, Martha L

    2016-08-01

    Objectives To diagnose the capabilities that environmental authorities and the Ministry of Environment and Sustainable Development have to assume their role in environmental health, based on the capacity model of the United Nations Program for Development UNDP. Method Document review, interviews on key issues and a commented survey were conducted. 84 entities were selected for a tailored survey; complete information was obtained from 76 institutions. Results The valuation of environment favorability was within the acceptable and unfavorable categories; knowledge management capabilities were found to be precarious and assessment of functional capabilities ranged between appropriate and acceptable. The assessment of specific capabilities had a rating of poor or barely acceptable. Conclusions Two major problems were found: a. The environmental authorities do not conceive or implement these capabilities based on the UNDP model but on the conventional model of the Ministry of Environment, Housing and Territorial Development; b. Environmental authorities show an incipient level of incorporation of environmental health policies in their field of action.

  8. Molecular Diagnostics for Precision Medicine in Colorectal Cancer: Current Status and Future Perspective.

    PubMed

    Chen, Guoli; Yang, Zhaohai; Eshleman, James R; Netto, George J; Lin, Ming-Tseh

    2016-01-01

    Precision medicine, a concept that has recently emerged and has been widely discussed, emphasizes tailoring medical care to individuals largely based on information acquired from molecular diagnostic testing. As a vital aspect of precision cancer medicine, targeted therapy has been proven to be efficacious and less toxic for cancer treatment. Colorectal cancer (CRC) is one of the most common cancers and among the leading causes for cancer related deaths in the United States and worldwide. By far, CRC has been one of the most successful examples in the field of precision cancer medicine, applying molecular tests to guide targeted therapy. In this review, we summarize the current guidelines for anti-EGFR therapy, revisit the roles of pathologists in an era of precision cancer medicine, demonstrate the transition from traditional "one test-one drug" assays to multiplex assays, especially by using next-generation sequencing platforms in the clinical diagnostic laboratories, and discuss the future perspectives of tumor heterogeneity associated with anti-EGFR resistance and immune checkpoint blockage therapy in CRC.

  9. The use of optical pyrometers in axial flow turbines

    NASA Astrophysics Data System (ADS)

    Sellers, R. R.; Przirembel, H. R.; Clevenger, D. H.; Lang, J. L.

    1989-07-01

    An optical pyrometer system that can be used to measure metal temperatures over an extended range of temperature has been developed. Real-time flame discrimination permits accurate operation in the gas turbine environment with high flame content. This versatile capability has been used in a number of ways. In experimental engines, a fixed angle pyrometer has been used for turbine health monitoring for the automatic test stand abort system. Turbine blade creep capability has been improved by tailoring the burner profile based on measured blade temperatures. Fixed and traversing pyrometers were used extensively during engine development to map blade surface temperatures in order to assess cooling effectiveness and identify optimum configurations. Portable units have been used in turbine field inspections. A new low temperature pyrometer is being used as a diagnostic tool in the alternate turbopump design for the Space Shuttle main engine. Advanced engine designs will incorporate pyrometers in the engine control system to limit operation to safe temperatures.

  10. A tailored relocation stress intervention programme for family caregivers of patients transferred from a surgical intensive care unit to a general ward.

    PubMed

    Lee, Seul; Oh, HyunSoo; Suh, YeonOk; Seo, WhaSook

    2017-03-01

    To develop and examine a relocation stress intervention programme tailored for the family caregivers of patients scheduled for transfer from a surgical intensive care unit to a general ward. Family relocation stress syndrome has been reported to be similar to that exhibited by patients, and investigators have emphasised that nurses should make special efforts to relieve family relocation stress to maximise positive contributions to the well-being of patients by family caregivers. A nonequivalent control group, nonsynchronised pretest-post-test design was adopted. The study subjects were 60 family caregivers of patients with neurosurgical or general surgical conditions in the surgical intensive care unit of a university hospital located in Incheon, South Korea. Relocation stress and family burden were evaluated at three times, that is before intervention, immediately after transfer and four to five days after transfer. This relocation stress intervention programme was developed for the family caregivers based on disease characteristics and relocation-related needs. In the experimental group, relocation stress levels significantly and continuously decreased after intervention, whereas in the control group, a slight nonsignificant trend was observed. Family burden levels in the control group increased significantly after transfer, whereas burden levels in the experimental group increased only marginally and nonsignificantly. No significant between-group differences in relocation stress or family burden levels were observed after intervention. Relocation stress levels of family caregivers were significantly decreased after intervention in the experimental group, which indicates that the devised family relocation stress intervention programme effectively alleviated family relocation stress. The devised intervention programme, which was tailored to disease characteristics and relocation-related needs, may enhance the practicality and efficacy of relocation stress management and make meaningful contribution to the relief of family relocation stress, promote patient recovery and enhance the well-being of patients and family caregivers. © 2016 John Wiley & Sons Ltd.

  11. Calibration Matters: Advances in Strapdown Airborne Gravimetry

    NASA Astrophysics Data System (ADS)

    Becker, D.

    2015-12-01

    Using a commercial navigation-grade strapdown inertial measurement unit (IMU) for airborne gravimetry can be advantageous in terms of cost, handling, and space consumption compared to the classical stable-platform spring gravimeters. Up to now, however, large sensor errors made it impossible to reach the mGal-level using such type IMUs as they are not designed or optimized for this kind of application. Apart from a proper error-modeling in the filtering process, specific calibration methods that are tailored to the application of aerogravity may help to bridge this gap and to improve their performance. Based on simulations, a quantitative analysis is presented on how much IMU sensor errors, as biases, scale factors, cross couplings, and thermal drifts distort the determination of gravity and the deflection of the vertical (DOV). Several lab and in-field calibration methods are briefly discussed, and calibration results are shown for an iMAR RQH unit. In particular, a thermal lab calibration of its QA2000 accelerometers greatly improved the long-term drift behavior. Latest results from four recent airborne gravimetry campaigns confirm the effectiveness of the calibrations applied, with cross-over accuracies reaching 1.0 mGal (0.6 mGal after cross-over adjustment) and DOV accuracies reaching 1.1 arc seconds after cross-over adjustment.

  12. Hydrogen storage and integrated fuel cell assembly

    DOEpatents

    Gross, Karl J.

    2010-08-24

    Hydrogen is stored in materials that absorb and desorb hydrogen with temperature dependent rates. A housing is provided that allows for the storage of one or more types of hydrogen-storage materials in close thermal proximity to a fuel cell stack. This arrangement, which includes alternating fuel cell stack and hydrogen-storage units, allows for close thermal matching of the hydrogen storage material and the fuel cell stack. Also, the present invention allows for tailoring of the hydrogen delivery by mixing different materials in one unit. Thermal insulation alternatively allows for a highly efficient unit. Individual power modules including one fuel cell stack surrounded by a pair of hydrogen-storage units allows for distribution of power throughout a vehicle or other electric power consuming devices.

  13. Cold cathode emission studies on topographically modified few layer and single layer MoS2 films

    NASA Astrophysics Data System (ADS)

    Gaur, Anand P. S.; Sahoo, Satyaprakash; Mendoza, Frank; Rivera, Adriana M.; Kumar, Mohit; Dash, Saroj P.; Morell, Gerardo; Katiyar, Ram S.

    2016-01-01

    Nanostructured materials, such as carbon nanotubes, are excellent cold cathode emitters. Here, we report comparative field emission (FE) studies on topographically tailored few layer MoS2 films consisting of ⟨0001⟩ plane perpendicular (⊥) to c-axis (i.e., edge terminated vertically aligned) along with planar few layer and monolayer (1L) MoS2 films. FE measurements exhibited lower turn-on field Eto (defined as required applied electric field to emit current density of 10 μA/cm2) ˜4.5 V/μm and higher current density ˜1 mA/cm2, for edge terminated vertically aligned (ETVA) MoS2 films. However, Eto magnitude for planar few layer and 1L MoS2 films increased further to 5.7 and 11 V/μm, respectively, with one order decrease in emission current density. The observed differences in emission behavior, particularly for ETVA MoS2 is attributed to the high value of geometrical field enhancement factor (β), found to be ˜1064, resulting from the large confinement of localized electric field at edge exposed nanograins. Emission behavior of planar few layers and 1L MoS2 films are explained under a two step emission mechanism. Our studies suggest that with further tailoring the microstructure of ultra thin ETVA MoS2 films would result in elegant FE properties.

  14. Monodispersed magnetite nanoparticles optimized for magnetic fluid hyperthermia: Implications in biological systems

    NASA Astrophysics Data System (ADS)

    Khandhar, Amit P.; Ferguson, R. Matthew; Krishnan, Kannan M.

    2011-04-01

    Magnetite (Fe3O4) nanoparticles (MNPs) are suitable materials for Magnetic Fluid Hyperthermia (MFH), provided their size is carefully tailored to the applied alternating magnetic field (AMF) frequency. Since aqueous synthesis routes produce polydisperse MNPs that are not tailored for any specific AMF frequency, we have developed a comprehensive protocol for synthesizing highly monodispersed MNPs in organic solvents, specifically tailored for our field conditions (f = 376 kHz, H0 = 13.4 kA/m) and subsequently transferred them to water using a biocompatible amphiphilic polymer. These MNPs (σavg. = 0.175) show truly size-dependent heating rates, indicated by a sharp peak in the specific loss power (SLP, W/g Fe3O4) for 16 nm (diameter) particles. For broader size distributions (σavg. = 0.266), we observe a 30% drop in overall SLP. Furthermore, heating measurements in biological medium [Dulbecco's modified Eagle medium (DMEM) + 10% fetal bovine serum] show a significant drop for SLP (˜30% reduction in 16 nm MNPs). Dynamic Light Scattering (DLS) measurements show particle hydrodynamic size increases over time once dispersed in DMEM, indicating particle agglomeration. Since the effective magnetic relaxation time of MNPs is determined by fractional contribution of the Neel (independent of hydrodynamic size) and Brownian (dependent on hydrodynamic size) components, we conclude that agglomeration in biological medium modifies the Brownian contribution and thus the net heating capacity of MNPs.

  15. Cost-effectiveness of targeted versus tailored interventions to promote mammography screening among women military veterans in the United States.

    PubMed

    Lairson, David R; Chan, Wen; Chang, Yu-Chia; del Junco, Deborah J; Vernon, Sally W

    2011-05-01

    We conducted an economic evaluation of mammography promotion interventions in a population-based, nationally representative sample of 5500 women veterans. Women 52 years and older were randomly selected from the National Registry of Women Veterans and randomly assigned to a survey-only control group and two intervention groups that varied in the extent of personalization (tailored vs. targeted). Effectiveness measures were the prevalence of at least one self-reported post-intervention mammogram and two post-intervention mammograms 6-15 months apart. Incremental cost-effectiveness ratios (ICERs) were the incremental cost per additional person screened. Uncertainty was examined with sensitivity analysis and bootstrap simulation. The targeted intervention cost $25 per person compared to $52 per person for the tailored intervention. About 27% of the cost was incurred in identifying and recruiting the eligible population. The percent of women reporting at least one mammogram were .447 in the control group, .469 in the targeted group, and .460 in the tailored group. The ICER was $1116 comparing the targeted group to the control group (95% confidence interval (CI)=$493 to dominated). The tailored intervention was dominated (more costly and less effective) by the targeted intervention. Decision-makers should consider effectiveness evidence and the full recruitment and patient time costs associated with the implementation of screening interventions when making investments in mammography screening promotion programs. Identification and recruitment of eligible participants add substantial costs to outreach screening promotion interventions. Tailoring adds substantial cost to the targeted mammography promotion strategy without a commensurate increase in effectiveness. Although cost-effectiveness has been reported to be higher for some in-reach screening promotion interventions, a recent meta-analysis revealed significant heterogeneity in the effect sizes of published health-plan based intervention studies for repeat mammography (i.e., some studies reported null effects compared with control groups). Copyright © 2010 Elsevier Ltd. All rights reserved.

  16. Tailored tobacco dependence support for mental health patients: a model for inpatient and community services.

    PubMed

    Parker, Camilla; McNeill, Ann; Ratschen, Elena

    2012-12-01

    Although smoking prevalence among people with severe mental illness is high, it remains largely unaddressed. This pragmatic pilot project aimed to develop and implement a tailored tobacco dependence service in mental health settings and to assess its impact, as well as barriers and facilitators to implementation. An integrative service model, spanning acute, rehabilitation and community services, including the design of tailored instruments and referral pathways, delivered by two mental health professionals. Four adult acute and two rehabilitation wards (129 beds), and the community recovery team (2038 cases) of the United Kingdom's largest Mental Health Trust. Audit of smoking information in patient notes; service uptake; quit attempts; smoking cessation and reduction; qualitative data on implementation barriers/facilitators. A total of 110 patients attended at least one support session: 53 inpatients (23% of inpatient smokers) and 57 community (of unknown number of community smokers, as recording of smoking status is not mandatory). Thirty-four of these (31%) made a quit attempt; 17 (15%) stopped smoking and 29 (26%) reduced cigarette consumption by up to 50% at the final contact. Barriers to service implementation related to: (i) trust policy, systems and procedures, (ii) staff knowledge and attitudes and (iii) illness-related factors. Despite the strong anti-smoking climate in the United Kingdom, including a law requiring smoke-free policies in mental health settings, establishing a smoking cessation treatment service for people with mental illness proved difficult, due to complex systemic barriers. However, there is clearly a demand, by patients, for such a service. © 2012 The Authors, Addiction © 2012 Society for the Study of Addiction.

  17. Basics of compounding: considerations for implementing United States pharmacopeia chapter 797 pharmaceutical compounding-sterile preparations, part 16: suggested standard operating procedures.

    PubMed

    Okeke, Claudia C; Allen, Loyd V

    2009-01-01

    The standard operating procedures suggested in this article are presented to compounding pharmacies to ensure the quality of the environment in which a CSP is prepared. Since United States Pharmacopeia Chapter 797 provides minimum standards, each facility should aim for best practice gold standard. The standard operating procedures should be tailored to meet the expectations and design of each facility. Compounding personnel are expected to know and understand each standard operating procedure to allow for complete execution of the procedures.

  18. Online Student Evaluation Improves Course Experience Questionnaire Results in a Physiotherapy Program

    ERIC Educational Resources Information Center

    Tucker, Beatrice; Jones, Sue; Straker, Leon

    2008-01-01

    This paper reports the use of an online student evaluation system, Course Experience on the Web (CEW), in a physiotherapy program to improve their Course Experience Questionnaire (CEQ) results. CEW comprises a course survey instrument modeled on the CEQ and a tailored unit survey instrument. Closure of the feedback loop is integral in the CEW…

  19. Validity Evidence for the Use of Holland's Vocational Personality Types in College Student Populations

    ERIC Educational Resources Information Center

    Floyd, Nancy D.

    2012-01-01

    Higher education in the United States is replete with inventories and instruments designed to help administrators to identify students who are more likely to succeed in college and to tailor the higher education experience to foster this success. One area of research involves the Holland vocational personality type (Holland 1973, 1985, 1997)…

  20. A Utilization Focused Evaluation: Aligning ISTE Standards within an Educational Technology Master's Program

    ERIC Educational Resources Information Center

    Finelli, Susan M.

    2012-01-01

    Preparing teachers for roles in 21st century learning environments has been a challenge for higher education institutions in the United States. In particular, researchers have documented that college preparatory programs should examine current standards as well as pertinent trends in the external environment as a means to tailor coursework. The…

  1. Brazil: The Fight for Childhood in the City. Innocenti Studies. The Urban Child in Difficult Circumstances.

    ERIC Educational Resources Information Center

    Swift, Anthony

    This publication is the second report, tailored to a non-specialist audience, of five country case studies under the Urban Child Program of the United Nations Children's Fund (UNICEF) International Child Development Center. The crisis of unprotected children and adolescents in Brazil has developed along with rapid industrialization and great…

  2. Randomized Trials on Consider This, a Tailored, Internet-Delivered Smoking Prevention Program for Adolescents

    ERIC Educational Resources Information Center

    Buller, David B.; Borland, Ron; Woodall, W. Gill; Hall, John R.; Hines, Joan M.; Burris-Woodall, Patricia; Cutter, Gary R.; Miller, Caroline; Balmford, James; Starling, Randall; Ax, Bryan; Saba, Laura

    2008-01-01

    The Internet may be an effective medium for delivering smoking prevention to children. Consider This, an Internet-based program, was hypothesized to reduce expectations concerning smoking and smoking prevalence. Group-randomized pretest-posttest controlled trials were conducted in Australia (n = 2,077) and the United States (n = 1,234) in schools…

  3. A tailored multicomponent program to reduce discomfort in critically ill patients: a cluster-randomized controlled trial.

    PubMed

    Kalfon, Pierre; Baumstarck, Karine; Estagnasie, Philippe; Geantot, Marie-Agnès; Berric, Audrey; Simon, Georges; Floccard, Bernard; Signouret, Thomas; Boucekine, Mohamed; Fromentin, Mélanie; Nyunga, Martine; Sossou, Achille; Venot, Marion; Robert, René; Follin, Arnaud; Audibert, Juliette; Renault, Anne; Garrouste-Orgeas, Maïté; Collange, Olivier; Levrat, Quentin; Villard, Isabelle; Thevenin, Didier; Pottecher, Julien; Patrigeon, René-Gilles; Revel, Nathalie; Vigne, Coralie; Azoulay, Elie; Mimoz, Olivier; Auquier, Pascal

    2017-12-01

    Critically ill patients are exposed to stressful conditions and experience several discomforts. The primary objective was to assess whether a tailored multicomponent program is effective for reducing self-perceived discomfort. In a cluster-randomized two-arm parallel trial, 34 French adult intensive care units (ICUs) without planned interventions to reduce discomfort were randomized, 17 to the arm including a 6-month period of program implementation followed by a 6-month period without the program (experimental group), and 17 to the arm with an inversed sequence (control group). The tailored multicomponent program consisted of assessment of ICU-related self-perceived discomforts, immediate and monthly feedback to healthcare teams, and site-specific tailored interventions. The primary outcome was the overall discomfort score derived from the 16-item IPREA questionnaire (0, minimal, 100, maximal overall discomfort) and the secondary outcomes were the discomfort scores of each IPREA item. IPREA was administered on the day of ICU discharge with a considered timeframe from the ICU admission until ICU discharge. During a 1-month assessment period, 398 and 360 patients were included in the experimental group and the control group, respectively. The difference (experimental minus control) of the overall discomfort score between groups was - 7.00 (95% CI - 9.89 to - 4.11, p < 0.001). After adjustment (age, gender, ICU duration, mechanical ventilation duration, and type of admission), the program effect was still positive for the overall discomfort score (difference - 6.35, SE 1.23, p < 0.001) and for 12 out of 16 items. This tailored multicomponent program decreased self-perceived discomfort in adult critically ill patients. Clinicaltrials.gov Identifier NCT02442934.

  4. Biosynthesis of ilamycins featuring unusual building blocks and engineered production of enhanced anti-tuberculosis agents.

    PubMed

    Ma, Junying; Huang, Hongbo; Xie, Yunchang; Liu, Zhiyong; Zhao, Jin; Zhang, Chunyan; Jia, Yanxi; Zhang, Yun; Zhang, Hua; Zhang, Tianyu; Ju, Jianhua

    2017-08-30

    Tuberculosis remains one of the world's deadliest communicable diseases, novel anti-tuberculosis agents are urgently needed due to severe drug resistance and the co-epidemic of tuberculosis/human immunodeficiency virus. Here, we show the isolation of six anti-mycobacterial ilamycin congeners (1-6) bearing rare L-3-nitro-tyrosine and L-2-amino-4-hexenoic acid structural units from the deep sea-derived Streptomyces atratus SCSIO ZH16. The biosynthesis of the rare L-3-nitrotyrosine and L-2-amino-4-hexenoic acid units as well as three pre-tailoring and two post-tailoring steps are probed in the ilamycin biosynthetic machinery through a series of gene inactivation, precursor chemical complementation, isotope-labeled precursor feeding experiments, as well as structural elucidation of three intermediates (6-8) from the respective mutants. Most impressively, ilamycins E 1 /E 2 , which are produced in high titers by a genetically engineered mutant strain, show very potent anti-tuberculosis activity with an minimum inhibitory concentration value ≈9.8 nM to Mycobacterium tuberculosis H37Rv constituting extremely potent and exciting anti-tuberculosis drug leads.Tuberculosis (TB) remains one of the world's deadliest communicable diseases, novel anti-TB agents are urgently needed due to severe drug resistance and the co-epidemic of TB/HIV. Here, the authors show that anti-mycobacterial ilamycin congeners bearing unusual structural units possess extremely potent anti-tuberculosis activities.

  5. Deformable membranes actuated by high mechanical power density composite electroactive polymers using tailored electric field

    NASA Technical Reports Server (NTRS)

    Bar-Cohen, Y.; Bhattacharya, K.

    2003-01-01

    The objective of the project was to develop a versatile electroactuator based on a specific class of EAP, conductive polymer, that is capable of developing high forces and displacements in both bending and linear contraction/expansion movements.

  6. Tailored semiconductors for high-harmonic optoelectronics.

    PubMed

    Sivis, Murat; Taucer, Marco; Vampa, Giulio; Johnston, Kyle; Staudte, André; Naumov, Andrei Yu; Villeneuve, D M; Ropers, Claus; Corkum, P B

    2017-07-21

    The advent of high-harmonic generation in gases 30 years ago set the foundation for attosecond science and facilitated ultrafast spectroscopy in atoms, molecules, and solids. We explore high-harmonic generation in the solid state by means of nanostructured and ion-implanted semiconductors. We use wavelength-selective microscopic imaging to map enhanced harmonic emission and show that the generation medium and the driving field can be locally tailored in solids by modifying the chemical composition and morphology. This enables the control of high-harmonic technology within precisely engineered solid targets. We demonstrate customized high-harmonic wave fields with wavelengths down to 225 nanometers (ninth-harmonic order of 2-micrometer laser pulses) and present an integrated Fresnel zone plate target in silicon, which leads to diffraction-limited self-focusing of the generated harmonics down to 1-micrometer spot sizes. Copyright © 2017 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

  7. Improved stability of the induced second-order nonlinearity in soft glass by thermal poling

    NASA Astrophysics Data System (ADS)

    Moura, A. L.; de Araujo, M. T.; Vermelho, M. V. D.; Aitchison, J. S.

    2006-08-01

    Stable and intense second-order nonlinearity in soda lime glass is investigated tailoring the induced electric current. This procedure allows the determination of the relative contributions of the dipole orientation as well as the ionic contributions to the poling process. The experiments are developed in the light of multiple-carrier models controlling the output power supply applied current to tailor the frozen-in induced electric field — Edc. This method permits the induction of the stable nonlinearity for applied electric fields above ˜5kV/cm and temperatures ˜250°C. It is also possible to reach higher temperatures than the ones used in normal poling procedures avoiding the electric current breakdown. The controlled Edc formation enables it to participate in essential chemical reactions that determine the intensity and stability of the nonlinearity. The induced d33 of ˜0.41pm/V measured 20 days after poling reduced only ˜50% during the next seven months.

  8. Scaling Effect on Unipolar and Bipolar Resistive Switching of Metal Oxides

    PubMed Central

    Yanagida, Takeshi; Nagashima, Kazuki; Oka, Keisuke; Kanai, Masaki; Klamchuen, Annop; Park, Bae Ho; Kawai, Tomoji

    2013-01-01

    Electrically driven resistance change in metal oxides opens up an interdisciplinary research field for next-generation non-volatile memory. Resistive switching exhibits an electrical polarity dependent “bipolar-switching” and a polarity independent “unipolar-switching”, however tailoring the electrical polarity has been a challenging issue. Here we demonstrate a scaling effect on the emergence of the electrical polarity by examining the resistive switching behaviors of Pt/oxide/Pt junctions over 8 orders of magnitudes in the areas. We show that the emergence of two electrical polarities can be categorised as a diagram of an electric field and a cell area. This trend is qualitatively common for various oxides including NiOx, CoOx, and TiO2-x. We reveal the intrinsic difference between unipolar switching and bipolar switching on the area dependence, which causes a diversity of an electrical polarity for various resistive switching devices with different geometries. This will provide a foundation for tailoring resistive switching behaviors of metal oxides. PMID:23584551

  9. Magnetization switching behavior with competing anisotropies in epitaxial Co3FeN /MnN exchange-coupled bilayers

    NASA Astrophysics Data System (ADS)

    Hajiri, T.; Yoshida, T.; Jaiswal, S.; Filianina, M.; Borie, B.; Ando, H.; Asano, H.; Zabel, H.; Kläui, M.

    2016-11-01

    We report unusual magnetization switching processes and angular-dependent exchange bias effects in fully epitaxial Co3FeN /MnN bilayers, where magnetocrystalline anisotropy and exchange coupling compete, probed by longitudinal and transverse magneto-optic Kerr effect (MOKE) magnetometry. The MOKE loops show multistep jumps corresponding to the nucleation and propagation of 90∘ domain walls in as-grown bilayers. By inducing exchange coupling, we confirm changes of the magnetization switching process due to the unidirectional anisotropy field of the exchange coupling. Taking into account the experimentally obtained values of the fourfold magnetocrystalline anisotropy, the unidirectional anisotropy field, the exchange-coupling constant, and the uniaxial anisotropy including its direction, the calculated angular-dependent exchange bias reproduces the experimental results. These results demonstrate the essential role of the competition between magnetocrystalline anisotropy and exchange coupling for understanding and tailoring exchange-coupling phenomena usable for engineering switching in fully epitaxial bilayers made of tailored materials.

  10. Structured light generation by magnetic metamaterial half-wave plates at visible wavelength

    NASA Astrophysics Data System (ADS)

    Zeng, Jinwei; Luk, Ting S.; Gao, Jie; Yang, Xiaodong

    2017-12-01

    Metamaterial or metasurface unit cells functioning as half-wave plates play an essential role for realizing ideal Pancharatnam-Berry phase optical elements capable of tailoring light phase and polarization as desired. Complex light beam manipulation through these metamaterials or metasurfaces unveils new dimensions of light-matter interactions for many advances in diffraction engineering, beam shaping, structuring light, and holography. However, the realization of metamaterial or metasurface half-wave plates in visible spectrum range is still challenging mainly due to its specific requirements of strong phase anisotropy with amplitude isotropy in subwavelength scale. Here, we propose magnetic metamaterial structures which can simultaneously exploit the electric field and magnetic field of light for achieving the nanoscale half-wave plates at visible wavelength. We design and demonstrate the magnetic metamaterial half-wave plates in linear grating patterns with high polarization conversion purity in a deep subwavelength thickness. Then, we characterize the equivalent magnetic metamaterial half-wave plates in cylindrical coordinate as concentric-ring grating patterns, which act like an azimuthal half-wave plate and accordingly exhibit spatially inhomogeneous polarization and phase manipulations including spin-to-orbital angular momentum conversion and vector beam generation. Our results show potentials for realizing on-chip beam converters, compact holograms, and many other metamaterial devices for structured light beam generation, polarization control, and wavefront manipulation.

  11. Tailoring optical metamaterials to tune the atom-surface Casimir-Polder interaction.

    PubMed

    Chan, Eng Aik; Aljunid, Syed Abdullah; Adamo, Giorgio; Laliotis, Athanasios; Ducloy, Martial; Wilkowski, David

    2018-02-01

    Metamaterials are fascinating tools that can structure not only surface plasmons and electromagnetic waves but also electromagnetic vacuum fluctuations. The possibility of shaping the quantum vacuum is a powerful concept that ultimately allows engineering the interaction between macroscopic surfaces and quantum emitters such as atoms, molecules, or quantum dots. The long-range atom-surface interaction, known as Casimir-Polder interaction, is of fundamental importance in quantum electrodynamics but also attracts a significant interest for platforms that interface atoms with nanophotonic devices. We perform a spectroscopic selective reflection measurement of the Casimir-Polder interaction between a Cs(6P 3/2 ) atom and a nanostructured metallic planar metamaterial. We show that by engineering the near-field plasmonic resonances of the metamaterial, we can successfully tune the Casimir-Polder interaction, demonstrating both a strong enhancement and reduction with respect to its nonresonant value. We also show an enhancement of the atomic spontaneous emission rate due to its coupling with the evanescent modes of the nanostructure. Probing excited-state atoms next to nontrivial tailored surfaces is a rigorous test of quantum electrodynamics. Engineering Casimir-Polder interactions represents a significant step toward atom trapping in the extreme near field, possibly without the use of external fields.

  12. The Senior Companion Program Plus: A culturally tailored psychoeducational training program (innovative practice).

    PubMed

    Fields, Noelle L; Xu, Ling; Richardson, Virginia E; Parekh, Rupal; Ivey, Dorothea; Feinhals, Gretchen; Calhoun, Melanie

    2016-01-01

    A purposive sample of African American Senior Companions ( N = 23) participated in a 5-day, 20-hour psychoeducational training designed to address the unique cultural needs of African American dementia caregivers. Previous studies have not utilized lay caregiver volunteers such as Senior Companions in dementia research in the United States. Pre- and post-tests were administered to determine whether African American Senior Companions increased their knowledge of Alzheimer's disease after participating in the Senior Companion Program Plus. Results from both the quantitative and qualitative data suggest that participants improved their understanding of Alzheimer's disease. Findings from the Senior Companion Program Plus pilot warrant further study for its potential as cost effective, culturally tailored training for Senior Companions who serve persons with dementia and their family caregivers.

  13. Tunability of soft phononic crystals through large deformation (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Bao, Ronghao; Chen, Weiqiu

    2017-04-01

    Phononic crystals (PCs) have attracted plenty of attention during the past two decades, and a lot of work has been devoted to the numerical, theoretical and experimental analysis of the band gaps of the PCs with 1D, 2D and 3D structures, respectively. The band gaps have been found to be related to the topology of the unit cell, filling ratio, contrast of the material properties between matrix and inclusion, and so on. However, they are fixed when the fabrication of corresponding devices is finished in most cases. Usually, biasing fields (e.g. initial stress, initial deformation, pre-existing electric field, external electric field and magnetic field, etc.) can be utilized to tailor the band gaps in flexible and reconfigurable ways. Recently, the instability-induced deformations triggered by external mechanical loadings have been found to be an effective and reversible way to tune the band gaps and the directionality of PCs made from soft materials, such as silicon and rubber. In this project, a novel design of PCs will be proposed, which consists of perforated plate with some individual beams fixed on the boundary of internal holes. When the external mechanical loading applied on the PCs reaches a threshold value, instability-induced buckling will be triggered and the internal beams might be in contact with each other, which will significantly alter the topology of PCs, and therefore effectively tune the band gaps of PCs. A systematical analysis will be carried out to study the influences on the tunability of PCs with different designs through finite element methods (FEM).

  14. Electric field control of the skyrmion lattice in Cu2OSeO3

    NASA Astrophysics Data System (ADS)

    White, J. S.; Levatić, I.; Omrani, A. A.; Egetenmeyer, N.; Prša, K.; Živković, I.; Gavilano, J. L.; Kohlbrecher, J.; Bartkowiak, M.; Berger, H.; Rønnow, H. M.

    2012-10-01

    Small-angle neutron scattering has been employed to study the influence of applied electric (E-)fields on the skyrmion lattice in the chiral lattice magnetoelectric Cu2OSeO3. Using an experimental geometry with the E-field parallel to the [111] axis, and the magnetic field parallel to the [1\\bar {1}0] axis, we demonstrate that the effect of applying an E-field is to controllably rotate the skyrmion lattice around the magnetic field axis. Our results are an important first demonstration for a microscopic coupling between applied E-fields and the skyrmions in an insulator, and show that the general emergent properties of skyrmions may be tailored according to the properties of the host system.

  15. Investigation of the flow structure in thin polymer films using 3D µPTV enhanced by GPU

    NASA Astrophysics Data System (ADS)

    Cavadini, Philipp; Weinhold, Hannes; Tönsmann, Max; Chilingaryan, Suren; Kopmann, Andreas; Lewkowicz, Alexander; Miao, Chuan; Scharfer, Philip; Schabel, Wilhelm

    2018-04-01

    To understand the effects of inhomogeneous drying on the quality of polymer coatings, an experimental setup to resolve the occurring flow field throughout the drying film has been developed. Deconvolution microscopy is used to analyze the flow field in 3D and time. Since the dimension of the spatial component in the direction of the line-of-sight is limited compared to the lateral components, a multi-focal approach is used. Here, the beam of light is equally distributed on up to five cameras using cubic beam splitters. Adding a meniscus lens between each pair of camera and beam splitter and setting different distances between each camera and its meniscus lens creates multi-focality and allows one to increase the depth of the observed volume. Resolving the spatial component in the line-of-sight direction is based on analyzing the point spread function. The analysis of the PSF is computational expensive and introduces a high complexity compared to traditional particle image velocimetry approaches. A new algorithm tailored to the parallel computing architecture of recent graphics processing units has been developed. The algorithm is able to process typical images in less than a second and has further potential to realize online analysis in the future. As a prove of principle, the flow fields occurring in thin polymer solutions drying at ambient conditions and at boundary conditions that force inhomogeneous drying are presented.

  16. The Afterschool Experience in "Salsa, Sabor y Salud": Evaluation, 2007-2008. CRESST Report 747

    ERIC Educational Resources Information Center

    Huang, Denise; La Torre, Deborah; Oh, Christine; Harven, Aletha; Huber, Lindsay; Leon, Seth; Mostafavi, Sima

    2008-01-01

    In the United States, there is an alarming trend toward obesity and inactivity among children. Minorities and economically disadvantaged children are at an even higher risk. According to the Centers for Disease Control and Prevention one in two Latino children will become diabetic. As a result, there is a dire need for tailored intervention…

  17. A Comparison of an Individually Tailored and a Standardized Asthma Self-Management Education

    ERIC Educational Resources Information Center

    Shackelford, Judy; Bachman, Jean H.

    2009-01-01

    Background: Asthma is one of the most prevalent chronic diseases in the United States and can be life-threatening. There are a rising number of adults with asthma that cannot be prevented or cured but may be controlled. Self-management education is essential for long-term asthma control; however, the most effective type of education is unknown.…

  18. From McGuffey Readers To Taking Notes on the Sermon: Literacy Experiences in a Catholic Home Schooling Group.

    ERIC Educational Resources Information Center

    Altieri, Jennifer L.

    2000-01-01

    Looks at the literacy practices of a Catholic home schooling group located in the United States Pacific Northwest. Finds that reading aloud was important to all parents. Notes some benefits cited by parents including immediate feedback for children, ability to pace themselves as necessary, and the opportunity to tailor lessons to individual…

  19. Southern Seven Women's Initiative for Cardiovascular Health: Lessons Learned in Community Health Outreach with Rural Women

    ERIC Educational Resources Information Center

    Zimmermann, Kristine; Khare, Manorama M.; Huber, Rachel; Moehring, Patricia A.; Koch, Abby; Geller, Stacie E.

    2012-01-01

    Background: Cardiovascular disease is the leading cause of death in women in the United States. Rural women have an increased risk of cardiovascular disease due to both behavioral and environmental factors. Models of prevention that are tailored to community needs and build on existing resources are essential for effective outreach to rural women.…

  20. Assessing the Effectiveness of One Approach to the Teaching of Thematic Unit Construction of Literature Reviews

    ERIC Educational Resources Information Center

    Bitchener, John; Turner, Elizabeth

    2011-01-01

    Despite the availability of practitioner advice on the characteristics of a literature review, students often report that they are unclear about what content should be included and how it can be most effectively organised. To assist them, some institutions provide courses that are specially tailored to the writing of thesis part-genres but very…

  1. Tailoring Shared Governance to the Needs and Opportunities of the Times. Research & Occasional Paper Series: CSHE.13.13

    ERIC Educational Resources Information Center

    King, C. Judson

    2013-01-01

    Shared governance between the administration and faculty has been traditional for most public universities, but varies considerably in its nature and effectiveness. In the United States it probably takes its most structured form at the University of California. There are good reasons for having shared governance, and yet it tends to be poorly…

  2. Strategic forum. Number 70. Regional deterrence strategies for new proliferation threats

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kahan, J.H.

    1996-04-01

    The deterrence of armed aggression against the United States, its vital national interests, or its allies has moved beyond the requirements of conventional force deterrence. The proliferation of nuclear, biological, and chemical (NBC) weapons requires a new strategy to ensure effective deterrence against their use by regional states that could not win in a conventional conflict with the United States. Because proliferation has expanded to a number of regional actors, a single strategy is unlikely to be sufficient in deterring states with varied motivations, and social, economic, religious, cultural, and political backgrounds. The Unified Commands-principally the Pacific, Central and Europeanmore » Commands- provide a ready-made framework in which general U.S. deterrence strategies can be tailored to each proliferant state While the Unified Commands would shape the individual deterrence strategies, the national command authority (NCA) would retain control of key decisions. Guidelines for NBC regional deterrence should include developing credible counterproliferation postures, profiling potential adversaries, tailoring our military capabilities to specific threats, integrating NBC preparedness into exercises and warplans, and actively pursuing coalitions designed to deter regional proliferators from threatening to use or using NBC weapons.« less

  3. Silver nanoparticles as a key feature of a plasma polymer composite layer in mitigation of charge injection into polyethylene under dc stress

    NASA Astrophysics Data System (ADS)

    Milliere, L.; Maskasheva, K.; Laurent, C.; Despax, B.; Boudou, L.; Teyssedre, G.

    2016-01-01

    The aim of this work is to limit charge injection from a semi-conducting electrode into low density polyethylene (LDPE) under dc field by tailoring the polymer surface using a silver nanoparticles-containing layer. The layer is composed of a plane of silver nanoparticles embedded in a semi-insulating organosilicon matrix deposited on the polyethylene surface by a plasma process. Size, density and surface coverage of the nanoparticles are controlled through the plasma process. Space charge distribution in 300 μm thick LDPE samples is measured by the pulsed-electroacoustic technique following a short term (step-wise voltage increase up to 50 kV mm-1, 20 min in duration each, followed by a polarity inversion) and a longer term (up to 12 h under 40 kV mm-1) protocols for voltage application. A comparative study of space charge distribution between a reference polyethylene sample and the tailored samples is presented. It is shown that the barrier effect depends on the size distribution and the surface area covered by the nanoparticles: 15 nm (average size) silver nanoparticles with a high surface density but still not percolating form an efficient barrier layer that suppress charge injection. It is worthy to note that charge injection is detected for samples tailored with (i) percolating nanoparticles embedded in organosilicon layer; (ii) with organosilicon layer only, without nanoparticles and (iii) with smaller size silver particles (<10 nm) embedded in organosilicon layer. The amount of injected charges in the tailored samples increases gradually in the samples ranking given above. The mechanism of charge injection mitigation is discussed on the basis of complementary experiments carried out on the nanocomposite layer such as surface potential measurements. The ability of silver clusters to stabilize electrical charges close to the electrode thereby counterbalancing the applied field appears to be a key factor in explaining the charge injection mitigation effect.

  4. Ultrashort polarization-tailored bichromatic fields

    NASA Astrophysics Data System (ADS)

    Kerbstadt, Stefanie; Englert, Lars; Bayer, Tim; Wollenhaupt, Matthias

    2017-06-01

    We present a novel concept for the generation of ultrashort polarization-shaped bichromatic laser fields. The scheme utilizes a 4f polarization pulse shaper based on a liquid crystal spatial light modulator for independent amplitude and phase modulation of femtosecond laser pulses. By choice of either a conventional (p) or a composite (p-s) polarizer in the Fourier plane, the shaper setup enables the generation of parallel linearly and orthogonal linearly polarized bichromatic fields. Additional use of a ? wave plate behind the setup yields co-rotating and counter-rotating circularly polarized bichromatic fields. The scheme allows to independently control the spectral amplitude, phase and polarization profile of the output fields, offering an enormous versatility of bichromatic waveforms.

  5. The use of magnetic fields in vertical Bridgman/Gradient Freeze-type crystal growth

    NASA Astrophysics Data System (ADS)

    Pätzold, Olf; Niemietz, Kathrin; Lantzsch, Ronny; Galindo, Vladimir; Grants, Ilmars; Bellmann, Martin; Gerbeth, Gunter

    2013-03-01

    This paper outlines advanced vertical Bridgman/Gradient Freeze techniques with flow control using magnetic fields developed for the growth of semiconductor crystals. Low-temperature flow modelling, as well as laboratory-scaled crystal growth under the influence of rotating, travelling, and static magnetic fields are presented. Experimental and numerical flow modelling demonstrate the potential of the magnetic fields to establish a well-defined flow for tailoring heat and mass transfer in the melt during growth. The results of the growth experiments are discussed with a focus on the influence of a rotating field on the segregation of dopants, the influence of a travelling field on the temperature field and thermal stresses, and the potential of rotating and static fields for a stabilization of the melt flow.

  6. Technologies for Developing Predictive Atomistic and Coarse-Grained Force Fields for Ionic Liquid Property Prediction

    DTIC Science & Technology

    2008-07-29

    studied are set to zero and a constrained MM minimization is performed. It is critical that all other force field parameters (for bonds, angles, charges...identifying the symmetry of the problem and tailoring the parameterization accordingly may be critical . For Phase I, the above described procedure was...tasks and the evaluation of their properties. The tremendous number of possible ionic liquids that are within reach makes it critical that a reliable

  7. Electron acceleration and kinetic energy tailoring via ultrafast terahertz fields.

    PubMed

    Greig, S R; Elezzabi, A Y

    2014-11-17

    We propose a mechanism for tuning the kinetic energy of surface plasmon generated electron pulses through control of the time delay between a pair of externally applied terahertz pulses. Varying the time delay results in translation, compression, and broadening of the kinetic energy spectrum of the generated electron pulse. We also observe that the electrons' kinetic energy dependence on the carrier envelope phase of the surface plasmon is preserved under the influence of a terahertz electric field.

  8. The Effectiveness of a Web-Based Computer-Tailored Intervention on Workplace Sitting: A Randomized Controlled Trial.

    PubMed

    De Cocker, Katrien; De Bourdeaudhuij, Ilse; Cardon, Greet; Vandelanotte, Corneel

    2016-05-31

    Effective interventions to influence workplace sitting are needed, as office-based workers demonstrate high levels of continued sitting, and sitting too much is associated with adverse health effects. Therefore, we developed a theory-driven, Web-based, interactive, computer-tailored intervention aimed at reducing and interrupting sitting at work. The objective of our study was to investigate the effects of this intervention on objectively measured sitting time, standing time, and breaks from sitting, as well as self-reported context-specific sitting among Flemish employees in a field-based approach. Employees (n=213) participated in a 3-group randomized controlled trial that assessed outcomes at baseline, 1-month follow-up, and 3-month follow-up through self-reports. A subsample (n=122) were willing to wear an activity monitor (activPAL) from Monday to Friday. The tailored group received an automated Web-based, computer-tailored intervention including personalized feedback and tips on how to reduce or interrupt workplace sitting. The generic group received an automated Web-based generic advice with tips. The control group was a wait-list control condition, initially receiving no intervention. Intervention effects were tested with repeated-measures multivariate analysis of variance. The tailored intervention was successful in decreasing self-reported total workday sitting (time × group: P<.001), sitting at work (time × group: P<.001), and leisure time sitting (time × group: P=.03), and in increasing objectively measured breaks at work (time × group: P=.07); this was not the case in the other conditions. The changes in self-reported total nonworkday sitting, sitting during transport, television viewing, and personal computer use, objectively measured total sitting time, and sitting and standing time at work did not differ between conditions. Our results point out the significance of computer tailoring for sedentary behavior and its potential use in public health promotion, as the effects of the tailored condition were superior to the generic and control conditions. Clinicaltrials.gov NCT02672215; http://clinicaltrials.gov/ct2/show/NCT02672215 (Archived by WebCite at http://www.webcitation.org/6glPFBLWv).

  9. The Effectiveness of a Web-Based Computer-Tailored Intervention on Workplace Sitting: A Randomized Controlled Trial

    PubMed Central

    De Bourdeaudhuij, Ilse; Cardon, Greet; Vandelanotte, Corneel

    2016-01-01

    Background Effective interventions to influence workplace sitting are needed, as office-based workers demonstrate high levels of continued sitting, and sitting too much is associated with adverse health effects. Therefore, we developed a theory-driven, Web-based, interactive, computer-tailored intervention aimed at reducing and interrupting sitting at work. Objective The objective of our study was to investigate the effects of this intervention on objectively measured sitting time, standing time, and breaks from sitting, as well as self-reported context-specific sitting among Flemish employees in a field-based approach. Methods Employees (n=213) participated in a 3-group randomized controlled trial that assessed outcomes at baseline, 1-month follow-up, and 3-month follow-up through self-reports. A subsample (n=122) were willing to wear an activity monitor (activPAL) from Monday to Friday. The tailored group received an automated Web-based, computer-tailored intervention including personalized feedback and tips on how to reduce or interrupt workplace sitting. The generic group received an automated Web-based generic advice with tips. The control group was a wait-list control condition, initially receiving no intervention. Intervention effects were tested with repeated-measures multivariate analysis of variance. Results The tailored intervention was successful in decreasing self-reported total workday sitting (time × group: P<.001), sitting at work (time × group: P<.001), and leisure time sitting (time × group: P=.03), and in increasing objectively measured breaks at work (time × group: P=.07); this was not the case in the other conditions. The changes in self-reported total nonworkday sitting, sitting during transport, television viewing, and personal computer use, objectively measured total sitting time, and sitting and standing time at work did not differ between conditions. Conclusions Our results point out the significance of computer tailoring for sedentary behavior and its potential use in public health promotion, as the effects of the tailored condition were superior to the generic and control conditions. Trial Registration Clinicaltrials.gov NCT02672215; http://clinicaltrials.gov/ct2/show/NCT02672215 (Archived by WebCite at http://www.webcitation.org/6glPFBLWv) PMID:27245789

  10. Software Acquisition Improvement in the Aeronautical Systems Center

    DTIC Science & Technology

    2008-09-01

    software fielded, a variety of different methods were suggested by the interviewees. These included blocks, suites and other tailored processes developed...12 Selection of Research Method ...DoD look to the commercial market to buy tools, methods , environments, and application software, instead of custom-built software (DSB: 1987). These

  11. Strategies to Increase Filipino American Participation in Cardiovascular Health Promotion: A Systematic Review

    PubMed Central

    Gavero, Gretchenjan; Braun, Kathryn L.

    2018-01-01

    Introduction Cultural tailoring of interventions can be effective in reducing health disparities by attracting underserved populations to health promotion programs and improving their outcomes. The purpose of this systematic review was to assess what is known about increasing access to and participation in cardiovascular disease (CVD) prevention and control programs among Filipino Americans. Methods PubMed MEDLINE, CINAHL, and Sociologic Abstracts were searched for peer-reviewed studies and dissertations conducted in the United States from 2004 through 2016. Results A total of 347 articles were identified through the search, and 9 articles reporting on 7 interventions focused on CVD prevention in a Filipino American sample were included. All but one intervention used evidence-based curricula, and implementation varied across sites. All but 2 interventions used word-of-mouth advertising from friends, family, and community leaders to increase participation. The Filipino cultural values of food, social relationships, and family were prevalent aspects across interventions tailored for Filipino Americans. Aspects of spirituality and the arts were integrated into only 3 studies. Conclusion Given the burden of CVD in Filipino American populations, tailored interventions rooted in Filipino cultural values are vital to address this known health disparity. PMID:29786501

  12. Strategies to Increase Filipino American Participation in Cardiovascular Health Promotion: A Systematic Review.

    PubMed

    Domingo, Jermy-Leigh B; Gavero, Gretchenjan; Braun, Kathryn L

    2018-05-17

    Cultural tailoring of interventions can be effective in reducing health disparities by attracting underserved populations to health promotion programs and improving their outcomes. The purpose of this systematic review was to assess what is known about increasing access to and participation in cardiovascular disease (CVD) prevention and control programs among Filipino Americans. PubMed MEDLINE, CINAHL, and Sociologic Abstracts were searched for peer-reviewed studies and dissertations conducted in the United States from 2004 through 2016. A total of 347 articles were identified through the search, and 9 articles reporting on 7 interventions focused on CVD prevention in a Filipino American sample were included. All but one intervention used evidence-based curricula, and implementation varied across sites. All but 2 interventions used word-of-mouth advertising from friends, family, and community leaders to increase participation. The Filipino cultural values of food, social relationships, and family were prevalent aspects across interventions tailored for Filipino Americans. Aspects of spirituality and the arts were integrated into only 3 studies. Given the burden of CVD in Filipino American populations, tailored interventions rooted in Filipino cultural values are vital to address this known health disparity.

  13. [Information for teenagers with cancer: current state in French pediatric oncology units].

    PubMed

    Toutenu, Pauline; Chauvin, Franck

    2007-04-01

    In France, teenagers with cancer are managed mainly in paediatric units, given that there are only few teenage cancer units. This situation leads to the following question: are teenagers with cancer provided with tailored patient education? The object of this study was to identify education programmes specifically designed for teenagers in French paediatric oncology units. This study was conducted first by questionnaires, second by interviews with health care providers in units where information programs had been implemented. Nine information programmes or projects were identified: 2 booklets, one log book, one Web chat, one video, one DVD, one educative muppet, one peer based education group project, one nursing education session project and one qualitative study project. Only 5 from these programmes or project were specifically designed for teenagers. Four approaches can be identified: conception of education materials, individual patient education, group patient education, informal patient education.

  14. High-Performance Field Emission from a Carbonized Cork.

    PubMed

    Lee, Jeong Seok; Lee, Hak Jun; Yoo, Jae Man; Kim, Taewoo; Kim, Yong Hyup

    2017-12-20

    To broaden the range of application of electron beams, low-power field emitters are needed that are miniature and light. Here, we introduce carbonized cork as a material for field emitters. The light natural cork becomes a graphitic honeycomb upon carbonization, with the honeycomb cell walls 100-200 nm thick and the aspect ratio larger than 100, providing an ideal structure for the field electron emission. Compared to nanocarbon field emitters, the cork emitter produces a high current density and long-term stability with a low turn-on field. The nature of the cork material makes it quite simple to fabricate the emitter. Furthermore, any desired shape of the emitter tailored for the final application can easily be prepared for point, line, or planar emission.

  15. Directed-assembly of ordered nanoparticle arrays exploiting multiple adsorption mechanisms on a self-assembling biological template

    NASA Astrophysics Data System (ADS)

    Shindel, Matthew M.

    Developing processes to fabricate inorganic architectures with designer functionalities at increasingly minute length-scales is of chief concern in the fields of nanotechnology and nanoscience. This enterprise requires assembly mechanisms with the capacity to tailor both the spatial arrangement and material composition of a system's constituent building blocks. To this end, significant advances can be made by turning to biology, as the natural world has evolved the ability to generate intricate nanostructures, which can potentially be employed as templates for inorganic nanosystems. We explore this biotemplating methodology using two-dimensional streptavidin crystals, investigating the ability of the protein lattice to direct the assembly of ordered metallic nanoparticle arrays. We demonstrate that the adsorption of nanoparticles on the protein monolayer can be induced through both electrostatic and molecular recognition (ligand-receptor) interactions. Furthermore, the dynamics of adsorption can be modulated through both environmental factors (e.g. pH), and by tailoring particle surface chemistry. When the characteristic nanoparticle size is on the order of the biotemplate's unit-cell dimension, electrostatically-mediated adsorption occurs in a site-specific manner. The nanoparticles exhibit a pronounced preference for adhering to the areas between protein molecules. The two-dimensional structure of the resultant nanoparticle ensemble consequently conforms to that of the underlying protein crystal. Through theoretical calculations, simulation and experiment, we show that interparticle spacing in the templated array is influenced by the screened-coulombic repulsion between particles, and can thus be tuned by controlling ionic strength during deposition. Templating ordered nanoparticle arrays via ligand-receptor mediated adsorption, and the constrained growth of metallic nanoparticles directly on the protein lattice from ionic precursors are also examined. Overall, this work demonstrates that the streptavidin crystal system possesses unique utility for nanoscale, directed-assembly applications.

  16. The Invasive Species Forecasting System

    NASA Technical Reports Server (NTRS)

    Schnase, John; Most, Neal; Gill, Roger; Ma, Peter

    2011-01-01

    The Invasive Species Forecasting System (ISFS) provides computational support for the generic work processes found in many regional-scale ecosystem modeling applications. Decision support tools built using ISFS allow a user to load point occurrence field sample data for a plant species of interest and quickly generate habitat suitability maps for geographic regions of management concern, such as a national park, monument, forest, or refuge. This type of decision product helps resource managers plan invasive species protection, monitoring, and control strategies for the lands they manage. Until now, scientists and resource managers have lacked the data-assembly and computing capabilities to produce these maps quickly and cost efficiently. ISFS focuses on regional-scale habitat suitability modeling for invasive terrestrial plants. ISFS s component architecture emphasizes simplicity and adaptability. Its core services can be easily adapted to produce model-based decision support tools tailored to particular parks, monuments, forests, refuges, and related management units. ISFS can be used to build standalone run-time tools that require no connection to the Internet, as well as fully Internet-based decision support applications. ISFS provides the core data structures, operating system interfaces, network interfaces, and inter-component constraints comprising the canonical workflow for habitat suitability modeling. The predictors, analysis methods, and geographic extents involved in any particular model run are elements of the user space and arbitrarily configurable by the user. ISFS provides small, lightweight, readily hardened core components of general utility. These components can be adapted to unanticipated uses, are tailorable, and require at most a loosely coupled, nonproprietary connection to the Web. Users can invoke capabilities from a command line; programmers can integrate ISFS's core components into more complex systems and services. Taken together, these features enable a degree of decentralization and distributed ownership that have helped other types of scientific information services succeed in recent years.

  17. Flexible graphene/carbon nanotube hybrid papers chemical-reduction-tailored by gallic acid for high-performance electrochemical capacitive energy storages

    NASA Astrophysics Data System (ADS)

    Yao, Lu; Zhou, Chao; Hu, Nantao; Hu, Jing; Hong, Min; Zhang, Liying; Zhang, Yafei

    2018-03-01

    Mechanically robust graphene papers with both high gravimetric and volumetric capacitances are desired for high-performance energy storages. However, it's still a challenge to tailor the structure of graphene papers in order to meet this requirement. In this work, a kind of chemical-reduction-tailored mechanically-robust reduced graphene oxide/carbon nanotube hybrid paper has been reported for high-performance electrochemical capacitive energy storages. Gallic acid (GA), as an excellent reducing agent, was used to reduce graphene oxide. Through vacuum filtration of gallic acid reduced graphene oxide (GA-rGO) and carboxylic multiwalled carbon nanotubes (MWCNTs) aqueous suspensions, mechanically robust GA-rGO/MWCNTs hybrid papers were obtained. The resultant hybrid papers showed high gravimetric capacitance of 337.6 F g-1 (0.5 A g-1) and volumetric capacitance of 151.2 F cm-3 (0.25 A cm-3). In addition, the assembled symmetric device based on the hybrid papers exhibited high gravimetric capacitance of 291.6 F g-1 (0.5 A g-1) and volumetric capacitance of 136.6 F cm-3 (0.25 A cm-3). Meanwhile, it exhibited excellent rate capability and cycling stability. Above all, this chemical reduction tailoring technique and the resultant high-performance GA-rGO/MWCNTs hybrid papers give an insight for designing high-performance electrodes and hold a great potential in the field of energy storages.

  18. Vertical electrostatic actuator with extended digital range via tailored topology

    NASA Astrophysics Data System (ADS)

    Zhang, Yanhang; Dunn, Martin L.

    2002-07-01

    We describe the design, fabrication, and testing of an electrostatic vertical actuator that exhibits a range of motion that covers the entire initial gap between the actuator and substrate and provides controllable digital output motion. This is obtained by spatially tailoring the electrode arrangement and the stiffness characteristics of the microstructure to control the voltage-deflection characteristics. The concept is based on the electrostatic pull down of bimaterial beams, via a series of electrodes attached to the beams by flexures with tailored stiffness characteristics. The range of travel of the actuator is defined by the post-release deformed shape of the bilayer beams, and can be controlled by a post-release heat-treat process combined with a tailored actuator topology (material distribution and geometry, including spatial geometrical patterning of the individual layers of the bilayer beams). Not only does this allow an increase in the range of travel to cover the entire initial gap, but it also permits digital control of the tip of the actuator which can be designed to yield linear displacement - pull in step characteristics. We fabricated these actuators using the MUMPs surface micromachining process, and packaged them in-house. We measured, using an interferometric microscope, full field deformed shapes of the actuator at each pull in step. The measurements compare well with companion simulation results, both qualitatively and quantitatively.

  19. Tailor cutting of crystalline solar cells by laser micro jet

    NASA Astrophysics Data System (ADS)

    Bruckert, F.; Pilat, E.; Piron, P.; Torres, P.; Carron, B.; Richerzhagen, B.; Pirot, M.; Monna, R.

    2012-03-01

    Coupling a laser into a hair thin water micro jet (Laser Micro Jet, LMJ) for cutting applications offers a wide range of processes that are quite unique. As the laser beam is guided by internal reflections inside of a liquid cylinder, the cuts are naturally straight and do not reflect any divergence as otherwise occurs with an unguided laser beam. Furthermore, having a liquid media at the point of contact ensures a fast removal of heat and eventual debris ensuring clean cuts, which are free of any burrs. Many applications have indeed been developed for a large variety of materials, which are as different as e.g. diamond, silicon, aluminum, ceramic and hard metals. The photovoltaic industry has enjoyed in the last decades tremendous growth rates, which are still projected into the future. We focus here on the segment of Building Integrated PV (BIPV), which requests tailored solutions to actual buildings and not-one-fits-it-all standardized modules. Having the option to tailor cut solar cells opens a new field of BIPV applications. For the first time, finished crystalline solar cells have been LMJ cut into predetermined shapes. First results show that the cut is clean and neat. Preliminary solar performance measurements are positive. This opens a new avenue of tailored made modules instead of having to rely on the one-fits-alloy approach used so far.

  20. Modeling of fiber orientation in viscous fluid flow with application to self-compacting concrete

    NASA Astrophysics Data System (ADS)

    Kolařík, Filip; Patzák, Bořek

    2013-10-01

    In recent years, unconventional concrete reinforcement is of growing popularity. Especially fiber reinforcement has very wide usage in high performance concretes like "Self Compacting Concrete" (SCC). The design of advanced tailor-made structures made of SCC can take advantage of anisotropic orientation of fibers. Tools for fiber orientation predictions can contribute to design of tailor made structure and allow to develop casting procedures that enable to achieve the desired fiber distribution and orientation. This paper deals with development and implementation of suitable tool for prediction of fiber orientation in a fluid based on the knowledge of the velocity field. Statistical approach to the topic is employed. Fiber orientation is described by a probability distribution of the fiber angle.

  1. Quantitative magneto-optical investigation of superconductor/ferromagnet hybrid structures

    NASA Astrophysics Data System (ADS)

    Shaw, G.; Brisbois, J.; Pinheiro, L. B. G. L.; Müller, J.; Blanco Alvarez, S.; Devillers, T.; Dempsey, N. M.; Scheerder, J. E.; Van de Vondel, J.; Melinte, S.; Vanderbemden, P.; Motta, M.; Ortiz, W. A.; Hasselbach, K.; Kramer, R. B. G.; Silhanek, A. V.

    2018-02-01

    We present a detailed quantitative magneto-optical imaging study of several superconductor/ferromagnet hybrid structures, including Nb deposited on top of thermomagnetically patterned NdFeB and permalloy/niobium with erasable and tailored magnetic landscapes imprinted in the permalloy layer. The magneto-optical imaging data are complemented with and compared to scanning Hall probe microscopy measurements. Comprehensive protocols have been developed for calibrating, testing, and converting Faraday rotation data to magnetic field maps. Applied to the acquired data, they reveal the comparatively weaker magnetic response of the superconductor from the background of larger fields and field gradients generated by the magnetic layer.

  2. Tailoring health programming to clergy: findings from a study of United Methodist clergy in North Carolina.

    PubMed

    Proeschold-Bell, Rae Jean; LeGrand, Sara; Wallace, Amanda; James, John; Moore, H Edgar; Swift, Robin; Toole, David

    2012-01-01

    Research indicating high rates of chronic disease among some clergy groups highlights the need for health programming for clergy. Like any group united by similar beliefs and norms, clergy may find culturally tailored health programming more accessible and effective. There is an absence of research on what aspects clergy find important for clergy health programs. We conducted 11 focus groups with United Methodist Church pastors and district superintendents. Participants answered open-ended questions about clergy health program desires and ranked program priorities from a list of 13 possible programs. Pastors prioritized health club memberships, retreats, personal trainers, mental health counseling, and spiritual direction. District superintendents prioritized for pastors: physical exams, peer support groups, health coaching, retreats, health club memberships, and mental health counseling. District superintendents prioritized for themselves: physical exams, personal trainers, health coaching, retreats, and nutritionists. Additionally, through qualitative analysis, nine themes emerged concerning health and health programs: (a) clergy defined health holistically, and they expressed a desire for (b) schedule flexibility, (c) accessibility in rural areas, (d) low cost programs, (e) institutional support, (f) education on physical health, and (g) the opportunity to work on their health in connection with others. They also expressed concern about (h) mental health stigma and spoke about (i) the tension between prioritizing healthy behaviors and fulfilling vocational responsibilities. The design of future clergy health programming should consider these themes and the priorities clergy identified for health programming.

  3. Teacher Autonomy in the United States: Establishing a Standard Definition, Validation of a Nationally Representative Construct and an Investigation of Policy Affected Teacher Groups

    ERIC Educational Resources Information Center

    Gwaltney, Kevin Dale

    2012-01-01

    This effort: 1) establishes an autonomy definition uniquely tailored for teaching, 2) validates a nationally generalizable teacher autonomy construct, 3) demonstrates that the model describes and explains the autonomy levels of particular teacher groups, and 4) verifies the construct can represent teacher autonomy in other empirical models. The…

  4. Staff Perspectives on the Use of a Computer-Based Concept for Lifestyle Intervention Implemented in Primary Health Care

    ERIC Educational Resources Information Center

    Carlfjord, Siw; Johansson, Kjell; Bendtsen, Preben; Nilsen, Per; Andersson, Agneta

    2010-01-01

    Objective: The aim of this study was to evaluate staff experiences of the use of a computer-based concept for lifestyle testing and tailored advice implemented in routine primary health care (PHC). Design: The design of the study was a cross-sectional, retrospective survey. Setting: The study population consisted of staff at nine PHC units in the…

  5. Young People in 1994: the Health Related Behaviour Questionnaire Results for 48,297 Pupils between the Ages of 11 and 16.

    ERIC Educational Resources Information Center

    Balding, John

    This report examines the results of the "Health Related Behaviour Questionnaire" given to 48,297 pupils between the ages of 11 and 16 in the United Kingdom. Survey services are tailored to suit a cooperative method of working between different agencies supporting health promotion at community level. Survey origin, development over time,…

  6. The Emperor’s New Clothes -- SF Force Structure and EAF Force Protection

    DTIC Science & Technology

    2002-07-01

    Competencies.129 USAF Major Commands and Wings should develop supporting Mission Essential Task Lists tailored to their specific situation. Outsourcing ...United States Marine Corps Command and Staff College Marine Corps University 2076 South Street Marine Corps Combat Development Command Quantico...Within current resource constraints, some present SF functions must be outsourced or reassigned, other present functions must be expanded, and some

  7. Use of Traveling Magnetic Fields to Control Melt Convection

    NASA Technical Reports Server (NTRS)

    Ramachandran, Narayanan; Mazuruk, Konstantin; Volz, Martin P.

    2000-01-01

    An axially traveling magnetic wave induces a meridional base flow in an electrically conducting molten cylindrical zone. This flow can be beneficial for crystal growth applications. In particular, it can be effectively used to stir the melt in long cylindrical columns. It can also be tailored to modify the thermal and species concentration fields in the melt and to control the interface shape of the growing crystal. The basic theory of such an application is developed and data from a preliminary mercury column experiment are presented.

  8. About to Graduate from High School? Consider Career Education Opportunities. EdSource Student/Parent Guide = Estas por graduarte de la escuela preparatoria? Considera oportunidades para seguir tu educacion de carrera. EdSource guia de estudiantes y padres

    ERIC Educational Resources Information Center

    EdSource, 2006

    2006-01-01

    Getting a sound education is important to a student's ability to make a good living in a field they will enjoy. For many students graduating from high school, that includes high quality career technical (or vocational) education tailored to a specific job. In California, such programs are available in a wide range of fields, from healthcare to the…

  9. Synthesis of ceramic-based porous gradient structures for applications in energy conversion and related fields

    NASA Astrophysics Data System (ADS)

    Graule, Thomas; Ozog, Paulina; Durif, Caroline; Wilkens-Heinecke, Judit; Kata, Dariusz

    2016-06-01

    Porous, graded ceramic structures are of high relevance in the field of energy conversion as well as in catalysis, and additionally in filtration technology and in biomedical applications. Among different technologies for the tailored design for such structures we demonstrate here a new environmental friendly UV curing-based concept to prepare laminated structures with pore sizes ranging from a few microns up to 50 microns in diameter and with porosities ranging from 10% up to 75 vol.% porosity.

  10. Tailoring dielectric resonator geometries for directional scattering and Huygens’ metasurfaces

    DOE PAGES

    Campione, Salvatore; Basilio, Lorena I.; Warne, Larry K.; ...

    2015-01-28

    In this paper we describe a methodology for tailoring the design of metamaterial dielectric resonators, which represent a promising path toward low-loss metamaterials at optical frequencies. We first describe a procedure to decompose the far field scattered by subwavelength resonators in terms of multipolar field components, providing explicit expressions for the multipolar far fields. We apply this formulation to confirm that an isolated high-permittivity dielectric cube resonator possesses frequency separated electric and magnetic dipole resonances, as well as a magnetic quadrupole resonance in close proximity to the electric dipole resonance. We then introduce multiple dielectric gaps to the resonator geometrymore » in a manner suggested by perturbation theory, and demonstrate the ability to overlap the electric and magnetic dipole resonances, thereby enabling directional scattering by satisfying the first Kerker condition. We further demonstrate the ability to push the quadrupole resonance away from the degenerate dipole resonances to achieve local behavior. These properties are confirmed through the multipolar expansion and show that the use of geometries suggested by perturbation theory is a viable route to achieve purely dipole resonances for metamaterial applications such as wave-front manipulation with Huygens’ metasurfaces. Our results are fully scalable across any frequency bands where high-permittivity dielectric materials are available, including microwave, THz, and infrared frequencies.« less

  11. Attitudes Towards Prenatal Genetic Counseling, Prenatal Genetic Testing, and Termination of Pregnancy among Southeast and East Asian Women in the United States.

    PubMed

    Tsai, Ginger J; Cameron, Carrie A; Czerwinski, Jennifer L; Mendez-Figueroa, Hector; Peterson, Susan K; Noblin, Sarah Jane

    2017-10-01

    Recognizing the heterogeneity of the Asian population with regards to acculturation, education, health awareness, and cultural values is vital for tailoring culturally sensitive and appropriate care. Prior studies show that cultural values influence perceptions of genetics within Asian populations. The reputation of the family unit factors into decisions such as pregnancy termination and disclosure of family medical history, and the nondirective model of American genetic counseling may conflict with the historical Asian model of paternalistic health care. Previous studies also provide conflicting evidence regarding correlations between education, acculturation, age, and awareness and perceptions of genetic testing. The aims of this study were to describe attitudes towards prenatal genetics among Southeast and East Asian women living in the United States for varying amounts of time and to explore sociocultural factors influencing those attitudes. Twenty-three Asian women who were members of Asian cultural organizations in the United States were interviewed via telephone about their attitudes towards prenatal genetic counseling, prenatal genetic testing, and termination of pregnancy. Responses were transcribed and coded for common themes using a thematic analysis approach. Four major themes emerged. In general, participants: (1) had diverse expectations for genetic counselors; (2) tended to weigh risks and benefits with regards to genetic testing decisions; (3) had mixed views on termination for lethal and non-lethal genetic conditions; and (4) identified cultural factors which influenced testing and termination such as lack of available resources, societal shame and stigma, and family pressure. These findings may allow prenatal genetic counselors to gain a richer, more nuanced understanding of their Asian patients and to offer culturally tailored prenatal genetic counseling.

  12. Tailoring reablement: A grounded theory study of establishing reablement in a community setting in Norway.

    PubMed

    Moe, Cathrine; Brinchmann, Berit Støre

    2018-01-01

    Reablement is an interprofessional, home-based rehabilitation service that aims to enable senior residents to cope with everyday life and to prevent functional impairments. Systematic accounts of what practitioners actually do when establishing reablement are lacking. This study aims to generate a grounded theory of practitioners' patterns of action when establishing reablement. The study is located in Norway, and grounded theory is the methodological approach. Data were collected from January 2014 to August 2016 through participant observations, focus group interviews and individual interviews. Informants are municipal healthcare employees in different organisational areas associated with the process of establishing reablement services (managers of conventional home care and representatives from the administration and service-provider offices). Altogether, 17 individuals are interviewed. The empirical data are analysed several times using open, selective and theoretical coding. The grounded theory, "tailoring reablement," includes three phases-replicating, adapting and establishing-and the strategies of collaborating, developing knowledge, habituating and filtering. The theory of tailoring reablement also includes the impact of the contextual factors. The study seeks to bridge the gap between research and practice. The theory of tailoring reablement emerges from an inductive approach and theorises participants' actions. The theory focuses on the phases from innovation to implementation. Establishing a new service model in a complex welfare setting requires a wide range of actors and agencies. Tailoring reablement also requires flexibility and professional autonomy. It is important to create terms and conditions for this within a stringent health and care service. The insights of this study have implications for practice development of reablement and can fit other public sector fields. © 2017 The Authors. Health and Social Care in the Community Published by John Wiley & Sons Ltd.

  13. Core Skills for Effective Science Communication: A Teaching Resource for Undergraduate Science Education

    ERIC Educational Resources Information Center

    Mercer-Mapstone, Lucy; Kuchel, Louise

    2017-01-01

    Science communication is a diverse and transdisciplinary field and is taught most effectively when the skills involved are tailored to specific educational contexts. Few academic resources exist to guide the teaching of communication with non-scientific audiences for an undergraduate science context. This mixed methods study aimed to explore what…

  14. Learning Style Activities for Computer Applications. Field Review.

    ERIC Educational Resources Information Center

    Patton, Jan

    This document contains a composite of learning activities for use in a secondary-level course in business computer applications. The collection is unique in that the individual learning activities constituting it have each been tailored to one or more of the diverse learning styles possessed by individual students. The activities are grouped into…

  15. 43 CFR 1610.4-2 - Development of planning criteria.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 43 Public Lands: Interior 2 2011-10-01 2011-10-01 false Development of planning criteria. 1610.4-2... Management Planning § 1610.4-2 Development of planning criteria. (a) The Field Manager will prepare criteria to guide development of the resource management plan or revision, to ensure: (1) It is tailored to...

  16. Drive Beam Shaping and Witness Bunch Generation for the Plasma Wakefield Accelerator

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    England, R. J.; Frederico, J.; Hogan, M. J.

    2010-11-04

    High transformer ratio operation of the plasma wake field accelerator requires a tailored drive beam current profile followed by a short witness bunch. We discuss techniques for generating the requisite dual bunches and for obtaining the desired drive beam profile, with emphasis on the FACET experiment at SLAC National Accelerator Laboratory.

  17. Novel Organic Synthesis through Ultrafast Chemistry.

    PubMed

    Wirth, Thomas

    2017-01-16

    How fast are flashes? The field of flow chemistry has recently received increasing attention owing to the availability of commercial flow equipment. New syntheses with very short-lived intermediates have been enabled by sub-millisecond mixing and reaction regimes in tailor-made flow devices. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  18. Hybrid materials science: a promised land for the integrative design of multifunctional materials

    NASA Astrophysics Data System (ADS)

    Nicole, Lionel; Laberty-Robert, Christel; Rozes, Laurence; Sanchez, Clément

    2014-05-01

    For more than 5000 years, organic-inorganic composite materials created by men via skill and serendipity have been part of human culture and customs. The concept of ``hybrid organic-inorganic'' nanocomposites exploded in the second half of the 20th century with the expansion of the so-called ``chimie douce'' which led to many collaborations between a large set of chemists, physicists and biologists. Consequently, the scientific melting pot of these very different scientific communities created a new pluridisciplinary school of thought. Today, the tremendous effort of basic research performed in the last twenty years allows tailor-made multifunctional hybrid materials with perfect control over composition, structure and shape. Some of these hybrid materials have already entered the industrial market. Many tailor-made multiscale hybrids are increasingly impacting numerous fields of applications: optics, catalysis, energy, environment, nanomedicine, etc. In the present feature article, we emphasize several fundamental and applied aspects of the hybrid materials field: bioreplication, mesostructured thin films, Lego-like chemistry designed hybrid nanocomposites, and advanced hybrid materials for energy. Finally, a few commercial applications of hybrid materials will be presented.

  19. Strain and deformations engineered germanene bilayer double gate-field effect transistor by first principles

    NASA Astrophysics Data System (ADS)

    Meher Abhinav, E.; Chandrasekaran, Gopalakrishnan; Kasmir Raja, S. V.

    2017-10-01

    Germanene, silicene, stanene, phosphorene and graphene are some of single atomic materials with novel properties. In this paper, we explored bilayer germanene-based Double Gate-Field Effect Transistor (DG-FET) with various strains and deformations using Density Functional Theory (DFT) and Green's approach by first-principle calculations. The DG-FET of 1.6 nm width, 6 nm channel length (Lch) and HfO2 as gate dielectric has been modeled. For intrinsic deformation of germanene bilayer, we have enforced minute mechanical deformation of wrap and twist (5°) and ripple (0.5 Å) on germanene bilayer channel material. By using NEGF formalism, I-V Characteristics of various strains and deformation tailored DG-FET was calculated. Our results show that rough edge and single vacancy (5-9) in bilayer germanene diminishes the current around 47% and 58% respectively as compared with pristine bilayer germanene. In case of strain tailored bilayer DG-FET, multiple NDR regions were observed which can be utilized in building stable multiple logic states in digital circuits and high frequency oscillators using negative resistive techniques.

  20. Cold atmospheric pressure plasma jets: Interaction with plasmid DNA and tailored electron heating using dual-frequency excitation

    NASA Astrophysics Data System (ADS)

    Niemi, K.; O'Neill, C.; Cox, L. J.; Waskoenig, J.; Hyland, W. B.; McMahon, S. J.; Reuter, S.; Currell, F. J.; Graham, W. G.; O'Connell, D.; Gans, T.

    2012-05-01

    Recent progress in plasma science and technology has enabled the development of a new generation of stable cold non-equilibrium plasmas operating at ambient atmospheric pressure. This opens horizons for new plasma technologies, in particular in the emerging field of plasma medicine. These non-equilibrium plasmas are very efficient sources for energy transport through reactive neutral particles (radicals and metastables), charged particles (ions and electrons), UV radiation, and electro-magnetic fields. The effect of a cold radio frequency-driven atmospheric pressure plasma jet on plasmid DNA has been investigated. The formation of double strand breaks correlates well with the atomic oxygen density. Taken with other measurements, this indicates that neutral components in the jet are effective in inducing double strand breaks. Plasma manipulation techniques for controlled energy delivery are highly desirable. Numerical simulations are employed for detailed investigations of the electron dynamics, which determines the generation of reactive species. New concepts based on nonlinear power dissipation promise superior strategies to control energy transport for tailored technological exploitations.

  1. Hybrid materials science: a promised land for the integrative design of multifunctional materials.

    PubMed

    Nicole, Lionel; Laberty-Robert, Christel; Rozes, Laurence; Sanchez, Clément

    2014-06-21

    For more than 5000 years, organic-inorganic composite materials created by men via skill and serendipity have been part of human culture and customs. The concept of "hybrid organic-inorganic" nanocomposites exploded in the second half of the 20th century with the expansion of the so-called "chimie douce" which led to many collaborations between a large set of chemists, physicists and biologists. Consequently, the scientific melting pot of these very different scientific communities created a new pluridisciplinary school of thought. Today, the tremendous effort of basic research performed in the last twenty years allows tailor-made multifunctional hybrid materials with perfect control over composition, structure and shape. Some of these hybrid materials have already entered the industrial market. Many tailor-made multiscale hybrids are increasingly impacting numerous fields of applications: optics, catalysis, energy, environment, nanomedicine, etc. In the present feature article, we emphasize several fundamental and applied aspects of the hybrid materials field: bioreplication, mesostructured thin films, Lego-like chemistry designed hybrid nanocomposites, and advanced hybrid materials for energy. Finally, a few commercial applications of hybrid materials will be presented.

  2. Polar Cation Ordering: A Route to Introducing >10% Bond Strain Into Layered Oxide Films

    DOE PAGES

    Nelson-Cheeseman, Brittany B.; Zhou, Hua; Balachandran, Prasanna V.; ...

    2014-09-05

    The 3d transition metal (M) perovskite oxides exhibit a remarkable array of properties, including novel forms of superconductivity, magnetism and multiferroicity. Strain can have a profound effect on many of these properties. This is due to the localized nature of the M 3d orbitals, where even small changes in the M–O bond lengths and M–O–M bond angles produced by strain can be used to tune the 3d– O 2p hybridization, creating large changes in electronic structure. We present a new route to strain the M–O bonds in epitaxial two-dimensional perovskite films by tailoring local electrostatic dipolar interactions within every formulamore » unit via atomic layer-by-layer synthesis. The response of the O anions to the resulting dipole electric fields distorts the M–O bonds by more than 10%, without changing substrate strain or chemical composition. We found that this distortion is largest for the apical oxygen atoms (O ap), and alters the transition metal valence state via self-doping without chemical substitution.« less

  3. Molecular Diagnostics for Precision Medicine in Colorectal Cancer: Current Status and Future Perspective

    PubMed Central

    Chen, Guoli; Yang, Zhaohai; Eshleman, James R.; Netto, George J.

    2016-01-01

    Precision medicine, a concept that has recently emerged and has been widely discussed, emphasizes tailoring medical care to individuals largely based on information acquired from molecular diagnostic testing. As a vital aspect of precision cancer medicine, targeted therapy has been proven to be efficacious and less toxic for cancer treatment. Colorectal cancer (CRC) is one of the most common cancers and among the leading causes for cancer related deaths in the United States and worldwide. By far, CRC has been one of the most successful examples in the field of precision cancer medicine, applying molecular tests to guide targeted therapy. In this review, we summarize the current guidelines for anti-EGFR therapy, revisit the roles of pathologists in an era of precision cancer medicine, demonstrate the transition from traditional “one test-one drug” assays to multiplex assays, especially by using next-generation sequencing platforms in the clinical diagnostic laboratories, and discuss the future perspectives of tumor heterogeneity associated with anti-EGFR resistance and immune checkpoint blockage therapy in CRC. PMID:27699178

  4. High-efficiency tri-band quasi-continuous phase gradient metamaterials based on spoof surface plasmon polaritons

    PubMed Central

    Li, Yongfeng; Ma, Hua; Wang, Jiafu; Pang, Yongqiang; Zheng, Qiqi; Chen, Hongya; Han, Yajuan; Zhang, Jieqiu; Qu, Shaobo

    2017-01-01

    A high-efficiency tri-band quasi-continuous phase gradient metamaterial is designed and demonstrated based on spoof surface plasmon polaritons (SSPPs). High-efficiency polarizaiton conversion transmission is firstly achieved via tailoring phase differece between the transmisive SSPP and the space wave in orthogonal directions. As an example, a tri-band circular-to-circular (CTC) polarization conversion metamateiral (PCM) was designed by a nonlinearly dispersive phase difference. Using such PCM unit cell, a tri-band quasi-continuous phase gradient metamaterial (PGM) was then realized by virtue of the Pancharatnam-Berry phase. The distribution of the cross-polarization transmission phase along the x-direction is continuous except for two infinitely small intervals near the phases 0° and 360°, and thus the phase gradient has definition at any point along the x-direction. The simulated normalized polarization conversion transmission spectrums together with the electric field distributions for circularly polarized wave and linearly polarized wave demonstrated the high-efficiency anomalous refraction of the quasi-continuous PGM. The experimental verification for the linearly polarized incidence was also provided. PMID:28079185

  5. Advances in synthetic gauge fields for light through dynamic modulation

    NASA Astrophysics Data System (ADS)

    Hey, Daniel; Li, Enbang

    2018-04-01

    Photons are weak particles that do not directly couple to magnetic fields. However, it is possible to generate a photonic gauge field by breaking reciprocity such that the phase of light depends on its direction of propagation. This non-reciprocal phase indicates the presence of an effective magnetic field for the light itself. By suitable tailoring of this phase, it is possible to demonstrate quantum effects typically associated with electrons, and, as has been recently shown, non-trivial topological properties of light. This paper reviews dynamic modulation as a process for breaking the time-reversal symmetry of light and generating a synthetic gauge field, and discusses its role in topological photonics, as well as recent developments in exploring topological photonics in higher dimensions.

  6. Energy density engineering via zero-admittance domains in all-dielectric stratified materials

    NASA Astrophysics Data System (ADS)

    Amra, Claude; Zerrad, Myriam; Lemarchand, Fabien; Lereu, Aude; Passian, Ali; Zapien, Juan Antonio; Lequime, Michel

    2018-02-01

    Emerging photonic, sensing, and quantum applications require high fields and tight localization but low power consumption. Spatial, spectral, and magnitude control of electromagnetic fields is of key importance for enabling experiments in atomic, molecular, and optical physics. We introduce the concept of zero-admittance domains as a mechanism for tailoring giant optical fields bound within or on the surface of dielectric media. The described mechanism permits the creation of highly localized fields of extreme amplitudes simultaneously for incident photons of multiple wavelengths and incidence angles but arbitrary polarization states. No material constraints are placed upon the bounding media. Both intrinsic and extrinsic potential practical limitations of the predicted field enhancement are analyzed and applications relevant to optical sensors and microsources are briefly discussed.

  7. Advances in synthetic gauge fields for light through dynamic modulation.

    PubMed

    Hey, Daniel; Li, Enbang

    2018-04-01

    Photons are weak particles that do not directly couple to magnetic fields. However, it is possible to generate a photonic gauge field by breaking reciprocity such that the phase of light depends on its direction of propagation. This non-reciprocal phase indicates the presence of an effective magnetic field for the light itself. By suitable tailoring of this phase, it is possible to demonstrate quantum effects typically associated with electrons, and, as has been recently shown, non-trivial topological properties of light. This paper reviews dynamic modulation as a process for breaking the time-reversal symmetry of light and generating a synthetic gauge field, and discusses its role in topological photonics, as well as recent developments in exploring topological photonics in higher dimensions.

  8. Advances in synthetic gauge fields for light through dynamic modulation

    PubMed Central

    Li, Enbang

    2018-01-01

    Photons are weak particles that do not directly couple to magnetic fields. However, it is possible to generate a photonic gauge field by breaking reciprocity such that the phase of light depends on its direction of propagation. This non-reciprocal phase indicates the presence of an effective magnetic field for the light itself. By suitable tailoring of this phase, it is possible to demonstrate quantum effects typically associated with electrons, and, as has been recently shown, non-trivial topological properties of light. This paper reviews dynamic modulation as a process for breaking the time-reversal symmetry of light and generating a synthetic gauge field, and discusses its role in topological photonics, as well as recent developments in exploring topological photonics in higher dimensions. PMID:29765688

  9. Waveform control of orientation-dependent ionization of DCl in few-cycle laser fields.

    PubMed

    Znakovskaya, I; von den Hoff, P; Schirmel, N; Urbasch, G; Zherebtsov, S; Bergues, B; de Vivie-Riedle, R; Weitzel, K-M; Kling, M F

    2011-05-21

    Strong few-cycle light fields with stable electric field waveforms allow controlling electrons on time scales down to the attosecond domain. We have studied the dissociative ionization of randomly oriented DCl in 5 fs light fields at 720 nm in the tunneling regime. Momentum distributions of D(+) and Cl(+) fragments were recorded via velocity-map imaging. A waveform-dependent anti-correlated directional emission of D(+) and Cl(+) fragments is observed. Comparison of our results with calculations indicates that tailoring of the light field via the carrier envelope phase permits the control over the orientation of DCl(+) and in turn the directional emission of charged fragments upon the breakup of the molecular ion. © The Owner Societies 2011

  10. Evaluation of General and Tailor Made Force Fields via X-ray Thermal Diffuse Scattering Using Molecular Dynamics and Monte Carlo Simulations of Crystalline Aspirin.

    PubMed

    Chan, Eric J; Neumann, Marcus A

    2018-04-10

    We have performed a comparison of the experimental thermal diffuse scattering (TDS) from crystalline Aspirin (form I) to that calculated from molecular dynamics (MD) simulations based on a variety of general force fields and a tailor-made force field (TMFF). A comparison is also made with Monte Carlo (MC) simulations which use a "harmonic network" approach to describe the intermolecular interactions. These comparisons were based on the hypothesis that TDS could be a useful experimental data in validation of such simulation parameter sets, especially when calculations of dynamical properties (e.g., thermodynamic free energies) from molecular crystals are concerned. Currently such a validation of force field parameters against experimental data is often limited to calculation of specific physical properties, e.g., absolute lattice energies usually at 0 K or heat capacity measurements. TDS harvested from in-house or synchrotron experiments comprises highly detailed structural information representative of the dynamical motions of the crystal lattice. Thus, TDS is a well-suited experimental data-driven means of cross validating theoretical approaches targeted at understanding dynamical properties of crystals. We found from the results of our investigation that the TMFF and COMPASS (from the commercial software "Materials Studio") parameter sets gave the best agreement with experiment. From our homologous MC simulation analysis we are able to show that force constants associated with the molecular torsion angles are likely to be a strong contributing factor for the apparent reason why these aforementioned force fields performed better.

  11. Adjusting the Ion Permeability of Polyelectrolyte Multilayers through Layer-by-Layer Assembly under a High Gravity Field.

    PubMed

    Jiang, Chao; Luo, Caijun; Liu, Xiaolin; Shao, Lei; Dong, Youqing; Zhang, Yingwei; Shi, Feng

    2015-05-27

    The layer-by-layer (LbL) assembled multilayer has been widely used as good barrier film or capsule due to the advantages of its flexible tailoring of film permeability and compactness. Although many specific systems have been proposed for film design, developing a versatile strategy to control film compactness remains a challenge. We introduced the simple mechanical energy of a high gravity field to the LbL assembly process to tailor the multilayer permeability through adjusting film compactness. By taking poly(diallyldimethylammonium chloride) (PDDA) and poly{1-4[4-(3-carboxy-4-hydroxyphenylazo)benzenesulfonamido]-1,2-ethanediyl sodium salt} (PAzo) as a model system, we investigated the LbL assembly process under a high gravity field. The results showed that the high gravity field introduced effectively accelerated the multilayer deposition process by 20-fold compared with conventional dipping assembly; the adsorption rate was positively dependent on the rotating speed of the high gravity equipment and the concentration of the building block solutions. More interestingly, the film compactness of the PDDA/PAzo multilayer prepared under the high gravity field increased remarkably with the growing rotational speed of the high gravity equipment, as demonstrated through comparisons of surface morphology, cyclic voltammetry curves, and photoisomerization kinetics of PDDA/PAzo multilayers fabricated through the conventional dipping method and through LbL assembly under a high gravity field, respectively. In this way, we have introduced a simple and versatile external form of mechanical energy into the LbL assembling process to improve film compactness, which should be useful for further applications in controlled ion permeability, anticorrosion, and drug loading.

  12. How to Produce a Reactor Neutron Spectrum Using a Proton Accelerator

    DOE PAGES

    Burns, Kimberly A.; Wootan, David W.; Gates, Robert O.; ...

    2015-06-18

    A method for reproducing the neutron energy spectrum present in the core of an operating nuclear reactor using an engineered target in an accelerator proton beam is proposed. The protons interact with a target to create neutrons through various (p,n) type reactions. Spectral tailoring of the emitted neutrons can be used to modify the energy of the generated neutron spectrum to represent various reactor spectra. Through the use of moderators and reflectors, the neutron spectrum can be modified to reproduce many different spectra of interest including spectra in small thermal test reactors, large pressurized water reactors, and fast reactors. Themore » particular application of this methodology is the design of an experimental approach for using an accelerator to measure the betas produced during fission to be used to reduce uncertainties in the interpretation of reactor antineutrino measurements. This approach involves using a proton accelerator to produce a neutron field representative of a power reactor, and using this neutron field to irradiate fission foils of the primary isotopes contributing to fission in the reactor, creating unstable, neutron rich fission products that subsequently beta decay and emit electron antineutrinos. A major advantage of an accelerator neutron source over a neutron beam from a thermal reactor is that the fast neutrons can be slowed down or tailored to approximate various power reactor spectra. An accelerator based neutron source that can be tailored to match various reactor neutron spectra provides an advantage for control in studying how changes in the neutron spectra affect parameters such as the resulting fission product beta spectrum.« less

  13. Theory of plasma confinement in non-axisymmetric magnetic fields.

    PubMed

    Helander, Per

    2014-08-01

    The theory of plasma confinement by non-axisymmetric magnetic fields is reviewed. Such fields are used to confine fusion plasmas in stellarators, where in contrast to tokamaks and reversed-field pinches the magnetic field generally does not possess any continuous symmetry. The discussion is focussed on magnetohydrodynamic equilibrium conditions, collisionless particle orbits, and the kinetic theory of equilbrium and transport. Each of these topics is fundamentally affected by the absence of symmetry in the magnetic field: the field lines need not trace out nested flux surfaces, the particle orbits may not be confined, and the cross-field transport can be very large. Nevertheless, by tailoring the magnetic field appropriately, well-behaved equilibria with good confinement can be constructed, potentially offering an attractive route to magnetic fusion. In this article, the mathematical apparatus to describe stellarator plasmas is developed from first principles and basic elements underlying confinement optimization are introduced.

  14. Manipulation of dielectric Rayleigh particles using highly focused elliptically polarized vector fields.

    PubMed

    Gu, Bing; Xu, Danfeng; Rui, Guanghao; Lian, Meng; Cui, Yiping; Zhan, Qiwen

    2015-09-20

    Generation of vectorial optical fields with arbitrary polarization distribution is of great interest in areas where exotic optical fields are desired. In this work, we experimentally demonstrate the versatile generation of linearly polarized vector fields, elliptically polarized vector fields, and circularly polarized vortex beams through introducing attenuators in a common-path interferometer. By means of Richards-Wolf vectorial diffraction method, the characteristics of the highly focused elliptically polarized vector fields are studied. The optical force and torque on a dielectric Rayleigh particle produced by these tightly focused vector fields are calculated and exploited for the stable trapping of dielectric Rayleigh particles. It is shown that the additional degree of freedom provided by the elliptically polarized vector field allows one to control the spatial structure of polarization, to engineer the focusing field, and to tailor the optical force and torque on a dielectric Rayleigh particle.

  15. Tailoring peripartum nursing care for women of advanced maternal age.

    PubMed

    Suplee, Patricia Dunphy; Dawley, Katy; Bloch, Joan Rosen

    2007-01-01

    Births to women of advanced maternal age have increased dramatically over the last decade in both the United States. The majority of women who deliver their first baby after age 35 are healthy and experience positive birth outcomes. According to current research, primigravidas over 35 tend to be educated consumers. Their physical and psychosocial needs differ from those of the mother in her 20s, due to advanced age and factors related to difficulty conceiving and life circumstances. This paper presents (a) an overview of the possible risks to outcomes of childbearing for women over the age of 35; (b) a discussion of how women of advanced maternal age may differ from younger women related to developmental stage, stress or anxiety or both, decision making, and support systems; and (c) an exploration of tailoring nursing care strategies during the peripartum period specifically for this age cohort.

  16. Children's health retention in South Korea and the United States: a cross-cultural comparison.

    PubMed

    McDowell, Betsy M; Chang, Nahn Joo; Choi, Sang Soon

    2003-12-01

    In recent decades, great strides have been made globally in decreasing child mortality. However, given that many countries still do not have basic healthcare, additional emphasis is being placed on health promotion activities among industrialized nations. As cultural differences of individual countries impact these health promotion practices, the cultural characteristics influencing children and families in two countries, South Korea and the United States, were compared. Major child health risk factors were examined, and health retention strategies tailored to the cultural characteristics and needs of the populations of each country are proposed, using the Neuman Systems Model as a guideline.

  17. Establishing and running a trauma and dissociation unit: a contemporary experience.

    PubMed

    Middleton, Warwick; Higson, David

    2004-12-01

    To evaluate the functioning of a trauma and dissociation unit that has run for the past 8 years in a private hospital, with particular regard to operating philosophy, operating parameters, challenges encountered, research and educational initiatives, and the applicability of the treatment model to other settings. Despite the challenges associated with significant difficulties in the corporate management of a private health-care system, it has been possible to operate an inpatient and day hospital programme tailored to the needs of patients in the dissociative spectrum, and the lessons learnt from this experience are valid considerations in the future planning of mental health services overall.

  18. Rodolfo's Casa Caribe in Cuba: Business, Law, and Ethics of Investing in a Start-Up in Havana

    ERIC Educational Resources Information Center

    Sulkowski, Adam J.

    2017-01-01

    This case study presents the true story of Rodolfo--a former tailor and attorney from the provinces of Cuba--who moved to Havana to start a hospitality business. In 2016, the author (referred to as Adam throughout the case study), a business law professor from the United States, visited Havana to interview Rodolfo and learn about the factors for…

  19. A Guide to Design Functional Molecular Liquids with Tailorable Properties using Pyrene-Fluorescence as a Probe.

    PubMed

    Lu, Fengniu; Takaya, Tomohisa; Iwata, Koichi; Kawamura, Izuru; Saeki, Akinori; Ishii, Masashi; Nagura, Kazuhiko; Nakanishi, Takashi

    2017-06-13

    Solvent-free, nonvolatile, room-temperature alkylated-π functional molecular liquids (FMLs) are rapidly emerging as a new generation of fluid matter. However, precision design to tune their physicochemical properties remains a serious challenge because the properties are governed by subtle π-π interactions among functional π-units, which are very hard to control and characterize. Herein, we address the issue by probing π-π interactions with highly sensitive pyrene-fluorescence. A series of alkylated pyrene FMLs were synthesized. The photophysical properties were artfully engineered with rational modulation of the number, length, and substituent motif of alkyl chains attached to the pyrene unit. The different emission from the excimer to uncommon intermediate to the monomer scaled the pyrene-pyrene interactions in a clear trend, from stronger to weaker to negligible. Synchronously, the physical nature of these FMLs was regulated from inhomogeneous to isotropic. The inhomogeneity, unexplored before, was thoroughly investigated by ultrafast time-resolved spectroscopy techniques. The result provides a clearer image of liquid matter. Our methodology demonstrates a potential to unambiguously determine local molecular organizations of amorphous materials, which cannot be achieved by conventional structural analysis. Therefore this study provides a guide to design alkylated-π FMLs with tailorable physicochemical properties.

  20. Modeling and Characterization of Electrical Resistivity of Carbon Composite Laminates

    NASA Astrophysics Data System (ADS)

    Yasuda, Hiromi

    Origami has recently received significant interest from the scientific and engineering communities as a method for designing building blocks of engineered structures to enhance their mechanical properties. However, the primary focus has been placed on their kinematic applications by leveraging the compactness and auxeticity of planar origami platforms. In this thesis, we study two different types of volumetric origami structures, Tachi-Miura Polyhedron (TMP) and Triangulated Cylindrical Origami (TCO), hierarchically from a single unit cell level to an assembly of multi-origami cells. We strategically assemble these origami cells into mechanical metamaterials and demonstrate their unique static/dynamic mechanical responses. In particular, these origami structures exhibit tailorable stiffness and strain softening/hardening behaviors, which leads to rich wave dynamics in origami-based architectures such as tunable frequency bands and new types of nonlinear wave propagations. One of the novel waveforms investigated in this thesis is the rarefaction solitary wave arising from strain-softening nature of origami unit cell. This unique wave dynamic mechanism is analyzed in numerical, analytical, and experimental approaches. By leveraging their tailorable folding mechanisms, the origami-based mechanical metamaterials can be used for designing new types of engineering devices and structures, not only for deployable space and disaster relief applications, but also for vibration filtering, impact mitigation, and energy harvesting.

  1. A perfect Fresnel acoustic reflector implemented by a Fano-resonant metascreen

    NASA Astrophysics Data System (ADS)

    Amin, M.; Siddiqui, O.; Farhat, M.; Khelif, A.

    2018-04-01

    We propose a perfectly reflecting acoustic metasurface which is designed by replacing the curved segments of the traditional Fresnel reflector by flat Fano-resonant sub-wavelength unit cells. To preserve the original Fresnel focusing mechanism, the unit cell phase follows a specific phase profile which is obtained by applying the generalized Snell's law and Fermat's principle. The reflected curved phase fronts are thus created at the air-metasurface boundary by tailoring the metasurface dispersion as dictated by Huygens' principle. Since the unit cells are implemented by sub-wavelength double slit-shaped cavity resonators, the impinging sound waves are perfectly reflected producing acoustic focusing with negligible absorption. We use plane-wave solution and full-wave simulations to demonstrate the focusing effects. The simulation results closely follow the analytical predictions.

  2. Tailoring entanglement through domain engineering in a lithium niobate waveguide

    PubMed Central

    Ming, Yang; Tan, Ai-Hong; Wu, Zi-Jian; Chen, Zhao-Xian; Xu, Fei; Lu, Yan-Qing

    2014-01-01

    We propose to integrate the electro-optic (EO) tuning function into on-chip domain engineered lithium niobate (LN) waveguide. Due to the versatility of LN, both the spontaneously parametric down conversion (SPDC) and EO interaction could be realized simultaneously. Photon pairs are generated through SPDC, and the formation of entangled state is modulated by EO processes. An EO tunable polarization-entangled photon state is proposed. Orthogonally-polarized and parallel-polarized entanglements of photon pairs are instantly switchable by tuning the applied field. The characteristics of the source are theoretically investigated showing adjustable bandwidths and high entanglement degrees. Moreover, other kinds of reconfigurable entanglement are also achievable based on suitable domain-design. We believe tailoring entanglement based on domain engineering is a very promising solution for next generation function-integrated quantum circuits. PMID:24770555

  3. Marine Polysaccharides in Pharmaceutical Applications: An Overview

    PubMed Central

    Laurienzo, Paola

    2010-01-01

    The enormous variety of polysaccharides that can be extracted from marine plants and animal organisms or produced by marine bacteria means that the field of marine polysaccharides is constantly evolving. Recent advances in biological techniques allow high levels of polysaccharides of interest to be produced in vitro. Biotechnology is a powerful tool to obtain polysaccharides from a variety of micro-organisms, by controlling the growth conditions in a bioreactor while tailoring the production of biologically active compounds. Following an overview of the current knowledge on marine polysaccharides, with special attention to potential pharmaceutical applications and to more recent progress on the discovering of new polysaccharides with biological appealing characteristics, this review will focus on possible strategies for chemical or physical modification aimed to tailor the final properties of interest. PMID:20948899

  4. Tailoring PKI for the battlespace

    NASA Astrophysics Data System (ADS)

    Covey, Carlin R.

    2003-07-01

    A Public Key Infrastructure (PKI) can provide useful communication protections for friendly forces in the battlespace. The PKI would be used in conjunction with communication facilities that are accorded physical and Type-1 cryptographic protections. The latter protections would safeguard the confidentiality and (optionally) the integrity of communications between enclaves of users, whereas the PKI protections would furnish identification, authentication, authorization and privacy services for individual users. However, Commercial-Off-the-Shelf (COTS) and most Government-Off-the-Shelf (GOTS) PKI solutions are not ideally tailored for the battlespace environment. Most PKI solutions assume a relatively static, high-bandwidth communication network, whereas communication links in the battlespace will be dynamically reconfigured and bandwidth-limited. Most enterprise-wide PKI systems assume that users will enroll and disenroll at an orderly pace, whereas the battlespace PKI "enterprise" will grow and shrink abruptly as units are deployed or withdrawn from the battlespace. COTS and GOTS PKIs are seldom required to incorporate temporary "enterprise mergers", whereas the battlespace "enterprise" will need to incorporate temporary coalitions of forces drawn from various nations. This paper addresses both well-known and novel techniques for tailoring PKI for the battlespace environment. These techniques include the design of the security architecture, the selection of appropriate options within PKI standards, and some new PKI protocols that offer significant advantages in the battlespace.

  5. Nanooptics for high efficient photon managment

    NASA Astrophysics Data System (ADS)

    Wyrowski, Frank; Schimmel, Hagen

    2005-09-01

    Optical systems for photon management, that is the generation of tailored electromagnetic fields, constitute one of the keys for innovation through photonics. An important subfield of photon management deals with the transformation of an incident light field into a field of specified intensity distribution. In this paper we consider some basic aspects of the nature of systems for those light transformations. It turns out, that the transversal redistribution of energy (TRE) is of central concern to achieve systems with high transformation efficiency. Besides established techniques nanostructured optical elements (NOE) are demanded to implement transversal energy redistribution. That builds a bridge between the needs of photon management, optical engineering, and nanooptics.

  6. Spatial two-photon coherence of the entangled field produced by down-conversion using a partially spatially coherent pump beam

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jha, Anand Kumar; Boyd, Robert W.

    2010-01-15

    We study the spatial coherence properties of the entangled two-photon field produced by parametric down-conversion (PDC) when the pump field is, spatially, a partially coherent beam. By explicitly treating the case of a pump beam of the Gaussian Schell-model type, we show that in PDC the spatial coherence properties of the pump field get entirely transferred to the spatial coherence properties of the down-converted two-photon field. As one important consequence of this study, we find that, for two-qubit states based on the position correlations of the two-photon field, the maximum achievable entanglement, as quantified by concurrence, is bounded by themore » degree of spatial coherence of the pump field. These results could be important by providing a means of controlling the entanglement of down-converted photons by tailoring the degree of coherence of the pump field.« less

  7. Dynamic nuclear magnetic resonance field sensing with part-per-trillion resolution

    NASA Astrophysics Data System (ADS)

    Gross, Simon; Barmet, Christoph; Dietrich, Benjamin E.; Brunner, David O.; Schmid, Thomas; Pruessmann, Klaas P.

    2016-12-01

    High-field magnets of up to tens of teslas in strength advance applications in physics, chemistry and the life sciences. However, progress in generating such high fields has not been matched by corresponding advances in magnetic field measurement. Based mostly on nuclear magnetic resonance, dynamic high-field magnetometry is currently limited to resolutions in the nanotesla range. Here we report a concerted approach involving tailored materials, magnetostatics and detection electronics to enhance the resolution of nuclear magnetic resonance sensing by three orders of magnitude. The relative sensitivity thus achieved amounts to 1 part per trillion (10-12). To exemplify this capability we demonstrate the direct detection and relaxometry of nuclear polarization and real-time recording of dynamic susceptibility effects related to human heart function. Enhanced high-field magnetometry will generally permit a fresh look at magnetic phenomena that scale with field strength. It also promises to facilitate the development and operation of high-field magnets.

  8. Tailored Magnetic Nanoparticles for Optimizing Magnetic Fluid Hyperthermia

    PubMed Central

    Khandhar, Amit; Ferguson, R. Matthew; Simon, Julian A.; Krishnan, Kannan M.

    2011-01-01

    Magnetic Fluid Hyperthermia (MFH) is a promising approach towards adjuvant cancer therapy that is based on the localized heating of tumors using the relaxation losses of iron oxide magnetic nanoparticles (MNPs) in alternating magnetic fields (AMF). In this study, we demonstrate optimization of MFH by tailoring MNP size to an applied AMF frequency. Unlike conventional aqueous synthesis routes, we use organic synthesis routes that offer precise control over MNP size (diameter ~ 10–25 nm), size distribution and phase purity. Furthermore, the particles are successfully transferred to the aqueous phase using a biocompatible amphiphilic polymer, and demonstrate long-term shelf life. A rigorous characterization protocol ensures that the water-stable MNPs meet all the critical requirements: (1) uniform shape and monodispersity, (2) phase purity, (3) stable magnetic properties approaching that of the bulk, (4) colloidal stability, (5) substantial shelf life and (6) pose no significant in vitro toxicity. Using a dedicated hyperthermia system, we then identified that 16 nm monodisperse MNPs (σ ~ 0.175) respond optimally to our chosen AMF conditions (f = 373 kHz, Ho = 14 kA/m); however, with a broader size distribution (σ ~ 0.284) the Specific Loss Power (SLP) decreases by 30%. Finally, we show that these tailored MNPs demonstrate maximum hyperthermia efficiency by reducing viability of Jurkat cells in vitro, suggesting our optimization translates truthfully to cell populations. In summary, we present a way to intrinsically optimize MFH by tailoring the MNPs to any applied AMF, a required precursor to optimize dose and time of treatment. PMID:22213652

  9. User-Centered Design of Learn to Quit, a Smoking Cessation Smartphone App for People With Serious Mental Illness

    PubMed Central

    Rizo, Javier; Zeng, Emily; Kientz, Julie A; Ries, Richard; Otis, Chad; Hernandez, Kayla

    2018-01-01

    Background Smoking rates in the United States have been reduced in the past decades to 15% of the general population. However, up to 88% of people with psychiatric symptoms still smoke, leading to high rates of disease and mortality. Therefore, there is a great need to develop smoking cessation interventions that have adequate levels of usability and can reach this population. Objective The objective of this study was to report the rationale, ideation, design, user research, and final specifications of a novel smoking cessation app for people with serious mental illness (SMI) that will be tested in a feasibility trial. Methods We used a variety of user-centered design methods and materials to develop the tailored smoking cessation app. This included expert panel guidance, a set of design principles and theory-based smoking cessation content, development of personas and paper prototyping, usability testing of the app prototype, establishment of app’s core vision and design specification, and collaboration with a software development company. Results We developed Learn to Quit, a smoking cessation app designed and tailored to individuals with SMI that incorporates the following: (1) evidence-based smoking cessation content from Acceptance and Commitment Therapy and US Clinical Practice Guidelines for smoking cessation aimed at providing skills for quitting while addressing mental health symptoms, (2) a set of behavioral principles to increase retention and comprehension of smoking cessation content, (3) a gamification component to encourage and sustain app engagement during a 14-day period, (4) an app structure and layout designed to minimize usability errors in people with SMI, and (5) a set of stories and visuals that communicate smoking cessation concepts and skills in simple terms. Conclusions Despite its increasing importance, the design and development of mHealth technology is typically underreported, hampering scientific innovation. This report describes the systematic development of the first smoking cessation app tailored to people with SMI, a population with very high rates of nicotine addiction, and offers new design strategies to engage this population. mHealth developers in smoking cessation and related fields could benefit from a design strategy that capitalizes on the role visual engagement, storytelling, and the systematic application of behavior analytic principles to deliver evidence-based content. PMID:29339346

  10. Engineering Encounters: Creating a Prosthetic Hand

    ERIC Educational Resources Information Center

    Cook, Kristin Leigh; Bush, Sarah B.; Cox, Richard

    2015-01-01

    The power of 3D printing technology has grown exponentially in just the past few years--people around the world are using 3D printers to prepare food, create tailored clothing, build cars and homes, and advance the medical field in ways that never seemed possible. In classrooms across the nation, 3D printers have become increasingly common because…

  11. Developing Research and Teaching Resources for the Study of Organizational Communication in Political Settings.

    ERIC Educational Resources Information Center

    Graber, Doris A.

    It is unfortunate that the field of organizational communication has neglected communication in political settings, because the bulk of students enrolled in social science curricula are likely to work in public or semipublic institutions. Problems unique to the political setting stem from the fact that most public agencies must tailor their…

  12. Photopolymerization Of Levitated Droplets

    NASA Technical Reports Server (NTRS)

    Rembaum, Alan; Rhim, Won-Kyu; Hyson, Michael T.; Chang, Manchium

    1989-01-01

    Experimental containerless process combines two established techniques to make variety of polymeric microspheres. In single step, electrostatically-levitated monomer droplets polymerized by ultraviolet light. Faster than multiple-step emulsion polymerization process used to make microspheres. Droplets suspended in cylindrical quadrupole electrostatic levitator. Alternating electrostatic field produces dynamic potential along axis. Process enables tailoring of microspheres for medical, scientific, and industrial applications.

  13. Ask the Cognitive Scientist: Does Tailoring Instruction to "Learning Styles" Help Students Learn?

    ERIC Educational Resources Information Center

    Willingham, Daniel T.

    2018-01-01

    In this regular "American Educator" column, findings from the field of cognitive science that are strong and clear enough to merit classroom application are considered. Research over the last 10 years measuring whether participants learn better when new content fits their purported learning style shows little to no support for style…

  14. Time-to-Event Analysis of Individual Variables Associated with Nursing Students' Academic Failure: A Longitudinal Study

    ERIC Educational Resources Information Center

    Dante, Angelo; Fabris, Stefano; Palese, Alvisa

    2013-01-01

    Empirical studies and conceptual frameworks presented in the extant literature offer a static imagining of academic failure. Time-to-event analysis, which captures the dynamism of individual factors, as when they determine the failure to properly tailor timely strategies, impose longitudinal studies which are still lacking within the field. The…

  15. [Interventional radiology and radiation therapy].

    PubMed

    Hadjiev, Janaki

    2015-04-26

    The revolutionary role of modern cross-sectional imaging, the improved target definition in CT/MRI image guided brachytherapy, the precise topography for applicator and anatomy contribute to a better knowledge and management of tumors and critical organs. Further developments and functional imaging is expected to lead to a broad use of patient tailored therapy in the field of interventional radiation oncology.

  16. Arden Syntax Clinical Foundation Framework for Event Monitoring in Intensive Care Units: Report on a Pilot Study.

    PubMed

    de Bruin, Jeroen S; Zeckl, Julia; Adlassnig, Katharina; Blacky, Alexander; Koller, Walter; Rappelsberger, Andrea; Adlassnig, Klaus-Peter

    2017-01-01

    The creation of clinical decision support systems has received a strong impulse over the last years, but their integration into a clinical routine has lagged behind, partly due to a lack of interoperability and trust by physicians. We report on the implementation of a clinical foundation framework in Arden Syntax, comprising knowledge units for (a) preprocessing raw clinical data, (b) the determination of single clinical concepts, and (c) more complex medical knowledge, which can be modeled through the composition and configuration of knowledge units in this framework. Thus, it can be tailored to clinical institutions or patients' caregivers. In the present version, we integrated knowledge units for several infection-related clinical concepts into the framework and developed a clinical event monitoring system over the framework that employs three different scenarios for monitoring clinical signs of bloodstream infection. The clinical event monitoring system was tested using data from intensive care units at Vienna General Hospital, Austria.

  17. Stress Levels of Nurses in Oncology Outpatient Units.

    PubMed

    Ko, Woonhwa; Kiser-Larson, Norma

    2016-04-01

    Oncology nursing is often a source of substantial stress for nurses. Many nurses, particularly novice nurses, have inadequate preparation to care for patients at the end of life and their families. Unless nurses prevent or manage work-related stress by using effective coping strategies, oncology nursing staff will continue to suffer from burnout and compassion fatigue. The purpose of this article is to identify stress levels and stressful factors of nurses working in oncology outpatient units and to explore coping behaviors for work-related stress of oncology staff nurses in outpatient units. A descriptive, cross-sectional design was used to identify stress levels and stressful factors for outpatient oncology nurses, investigate differences in stress levels among nurses' demographic characteristics, and explore coping behaviors of the nurses. Study participants (N = 40) included RNs and licensed practical nurses who completed the Nursing Stress Scale, three open-ended questions, and a demographic questionnaire. The highest sources of stress were workload and patient death and dying. Demographic variables of age and work experience in nursing showed a significant positive relationship to work-related stress scores. The three most frequently used coping behaviors were verbalizing, exercising or relaxing, and taking time for self. Continuing education programs on stress management are highly recommended. Outpatient oncology nurses should be nurtured and supported through tailored interventions at multiple levels to help them find effective coping strategies and develop self-care competencies. Although younger and less experienced nurses had lower mean stress scores than older and more experienced nurses, the continuing education programs and tailored interventions would be helpful for all oncology nursing staff.

  18. Second-harmonic generation using tailored whispering gallery modes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dumeige, Yannick; Feron, Patrice

    It has been shown that whispering gallery modes can be used to obtain a combination of modal and geometrical quasi-phase-matching in second-harmonic generation. This could be achieved in isotropic, nonferroelectric, strongly dispersive and highly nonlinear materials such as III-V semiconductors. Unfortunately the poor overlap between the second-harmonic field and second order nonlinear polarization limits the conversion efficiency. In this paper we show that by engineering the refractive index it is possible to increase field overlap and to enhance effective second order nonlinear polarization of semiconductor microdisks.

  19. Shear viscosity coefficient of liquid lanthanides

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Patel, H. P., E-mail: patel.harshal2@gmail.com; Thakor, P. B., E-mail: pbthakore@rediffmail.com; Prajapati, A. V., E-mail: anand0prajapati@gmail.com

    2015-05-15

    Present paper deals with the computation of shear viscosity coefficient (η) of liquid lanthanides. The effective pair potential v(r) is calculated through our newly constructed model potential. The Pair distribution function g(r) is calculated from PYHS reference system. To see the influence of local field correction function, Hartree (H), Tailor (T) and Sarkar et al (S) local field correction function are used. Present results are compared with available experimental as well as theoretical data. Lastly, we found that our newly constructed model potential successfully explains the shear viscosity coefficient (η) of liquid lanthanides.

  20. Shear viscosity coefficient of liquid lanthanides

    NASA Astrophysics Data System (ADS)

    Patel, H. P.; Sonvane, Y. A.; Thakor, P. B.; Prajapati, A. V.

    2015-05-01

    Present paper deals with the computation of shear viscosity coefficient (η) of liquid lanthanides. The effective pair potential v(r) is calculated through our newly constructed model potential. The Pair distribution function g(r) is calculated from PYHS reference system. To see the influence of local field correction function, Hartree (H), Tailor (T) and Sarkar et al (S) local field correction function are used. Present results are compared with available experimental as well as theoretical data. Lastly, we found that our newly constructed model potential successfully explains the shear viscosity coefficient (η) of liquid lanthanides.

  1. Saliency Detection on Light Field.

    PubMed

    Li, Nianyi; Ye, Jinwei; Ji, Yu; Ling, Haibin; Yu, Jingyi

    2017-08-01

    Existing saliency detection approaches use images as inputs and are sensitive to foreground/background similarities, complex background textures, and occlusions. We explore the problem of using light fields as input for saliency detection. Our technique is enabled by the availability of commercial plenoptic cameras that capture the light field of a scene in a single shot. We show that the unique refocusing capability of light fields provides useful focusness, depths, and objectness cues. We further develop a new saliency detection algorithm tailored for light fields. To validate our approach, we acquire a light field database of a range of indoor and outdoor scenes and generate the ground truth saliency map. Experiments show that our saliency detection scheme can robustly handle challenging scenarios such as similar foreground and background, cluttered background, complex occlusions, etc., and achieve high accuracy and robustness.

  2. Tuning spin-polarized transport in organic semiconductors

    NASA Astrophysics Data System (ADS)

    Mattana, Richard; Galbiati, Marta; Delprat, Sophie; Tatay, Sergio; Deranlot, Cyrile; Seneor, Pierre; Petroff, Frederic

    Molecular spintronics is an emerging research field at the frontier between organic chemistry and the spintronics. Compared to traditional inorganic materials molecules are flexible and can be easily tailored by chemical synthesis. Due to their theoretically expected very long spin lifetime, they were first only seen as the ultimate media for spintronics devices. It was recently that new spintronics tailoring could arise from the chemical versatility brought by molecules. The hybridization between a ferromagnet and molecules induces a spin dependent broadening and energy shifting of the molecular orbitals leading to an induced spin polarization on the first molecular layer. This spin dependent hybridization can be used to tailor the spin dependent transport in organic spintronics devices. We have studied vertical Co/Alq3/Co organic spin valves. The negative magnetoresistance observed is the signature of different coupling strengths at the top and bottom interfaces. We have then inserted an inorganic tunnel barrier at the bottom interface in order to suppress the spin-dependent hybridization. In this case we restore a positive magnetoresistance. This demonstrates that at the bottom Co/Alq3 interface a stronger coupling occurs which induces an inversion of the spin polarization.

  3. Process Design of Aluminum Tailor Heat Treated Blanks.

    PubMed

    Kahrimanidis, Alexander; Lechner, Michael; Degner, Julia; Wortberg, Daniel; Merklein, Marion

    2015-12-09

    In many industrials field, especially in the automotive sector, there is a trend toward lightweight constructions in order to reduce the weight and thereby the CO₂ and NO x emissions of the products. An auspicious approach within this context is the substitution of conventional deep drawing steel by precipitation hardenable aluminum alloys. However, based on the low formability, the application for complex stamping parts is challenging. Therefore, at the Institute of Manufacturing Technology, an innovative technology to enhance the forming limit of these lightweight materials was invented. The key idea of the so-called Tailor Heat Treated Blanks (THTB) is optimization of the mechanical properties by local heat treatment before the forming operation. An accurate description of material properties is crucial to predict the forming behavior of tailor heat treated blanks by simulation. Therefore, within in this research project, a holistic approach for the design of the THTB process in dependency of the main influencing parameters is presented and discussed in detail. The capability of the approach for the process development of complex forming operations is demonstrated by a comparison of local blank thickness of a tailgate with the corresponding results from simulation.

  4. Direct synthesis of antimicrobial coatings based on tailored bi-elemental nanoparticles

    NASA Astrophysics Data System (ADS)

    Benetti, Giulio; Cavaliere, Emanuele; Canteri, Adalberto; Landini, Giulia; Rossolini, Gian Maria; Pallecchi, Lucia; Chiodi, Mirco; Van Bael, Margriet J.; Winckelmans, Naomi; Bals, Sara; Gavioli, Luca

    2017-03-01

    Ultrathin coatings based on bi-elemental nanoparticles (NPs) are very promising to limit the surface-related spread of bacterial pathogens, particularly in nosocomial environments. However, tailoring the synthesis, composition, adhesion to substrate, and antimicrobial spectrum of the coating is an open challenge. Herein, we report on a radically new nanostructured coating, obtained by a one-step gas-phase deposition technique, and composed of bi-elemental Janus type Ag/Ti NPs. The NPs are characterized by a cluster-in-cluster mixing phase with metallic Ag nano-crystals embedded in amorphous TiO2 and present a promising antimicrobial activity including also multidrug resistant strains. We demonstrate the flexibility of the method to tune the embedded Ag nano-crystals dimension, the total relative composition of the coating, and the substrate type, opening the possibility of tailoring the dimension, composition, antimicrobial spectrum, and other physical/chemical properties of such multi-elemental systems. This work is expected to significantly spread the range of applications of NPs coatings, not only as an effective tool in the prevention of healthcare-associated infections but also in other technologically relevant fields like sensors or nano-/micro joining.

  5. Process Design of Aluminum Tailor Heat Treated Blanks

    PubMed Central

    Kahrimanidis, Alexander; Lechner, Michael; Degner, Julia; Wortberg, Daniel; Merklein, Marion

    2015-01-01

    In many industrials field, especially in the automotive sector, there is a trend toward lightweight constructions in order to reduce the weight and thereby the CO2 and NOx emissions of the products. An auspicious approach within this context is the substitution of conventional deep drawing steel by precipitation hardenable aluminum alloys. However, based on the low formability, the application for complex stamping parts is challenging. Therefore, at the Institute of Manufacturing Technology, an innovative technology to enhance the forming limit of these lightweight materials was invented. The key idea of the so-called Tailor Heat Treated Blanks (THTB) is optimization of the mechanical properties by local heat treatment before the forming operation. An accurate description of material properties is crucial to predict the forming behavior of tailor heat treated blanks by simulation. Therefore, within in this research project, a holistic approach for the design of the THTB process in dependency of the main influencing parameters is presented and discussed in detail. The capability of the approach for the process development of complex forming operations is demonstrated by a comparison of local blank thickness of a tailgate with the corresponding results from simulation. PMID:28793727

  6. Tuning and predicting the wetting of nanoengineered material surface

    NASA Astrophysics Data System (ADS)

    Ramiasa-MacGregor, M.; Mierczynska, A.; Sedev, R.; Vasilev, K.

    2016-02-01

    The wetting of a material can be tuned by changing the roughness on its surface. Recent advances in the field of nanotechnology open exciting opportunities to control macroscopic wetting behaviour. Yet, the benchmark theories used to describe the wettability of macroscopically rough surfaces fail to fully describe the wetting behaviour of systems with topographical features at the nanoscale. To shed light on the events occurring at the nanoscale we have utilised model gradient substrata where surface nanotopography was tailored in a controlled and robust manner. The intrinsic wettability of the coatings was varied from hydrophilic to hydrophobic. The measured water contact angle could not be described by the classical theories. We developed an empirical model that effectively captures the experimental data, and further enables us to predict the wetting of surfaces with nanoscale roughness by considering the physical and chemical properties of the material. The fundamental insights presented here are important for the rational design of advanced materials having tailored surface nanotopography with predictable wettability.The wetting of a material can be tuned by changing the roughness on its surface. Recent advances in the field of nanotechnology open exciting opportunities to control macroscopic wetting behaviour. Yet, the benchmark theories used to describe the wettability of macroscopically rough surfaces fail to fully describe the wetting behaviour of systems with topographical features at the nanoscale. To shed light on the events occurring at the nanoscale we have utilised model gradient substrata where surface nanotopography was tailored in a controlled and robust manner. The intrinsic wettability of the coatings was varied from hydrophilic to hydrophobic. The measured water contact angle could not be described by the classical theories. We developed an empirical model that effectively captures the experimental data, and further enables us to predict the wetting of surfaces with nanoscale roughness by considering the physical and chemical properties of the material. The fundamental insights presented here are important for the rational design of advanced materials having tailored surface nanotopography with predictable wettability. Electronic supplementary information (ESI) available: Detailed characterization of the nanorough substrates and model derivation. See DOI: 10.1039/c5nr08329j

  7. A systematic review of three approaches for constructing physical activity messages: What messages work and what improvements are needed?

    PubMed Central

    2010-01-01

    Background To motivate individuals to adhere to a regular physical activity regime, guidelines must be supplemented with persuasive messages that are disseminated widely. While substantial research has examined effective strategies for disseminating physical activity messages, there has been no systematic effort to examine optimal message content. This paper reviews studies that evaluate the effectiveness of three approaches for constructing physical activity messages including tailoring messages to suit individual characteristics of message recipients (message tailoring), framing messages in terms of gains versus losses (message framing), and targeting messages to affect change in self-efficacy (i.e., a theoretical determinant of behavior change). Methods We searched the MEDLINE, PsycINFO, EMBASE and CINAHL databases up to July 2008. Relevant reference lists also were searched. We included intervention trials, field experiments, and laboratory-based studies that aimed to test the efficacy or effectiveness of tailored messages, framed messages and self-efficacy change messages among healthy adults. We used a descriptive approach to analyze emerging patterns in research findings. Based on this evidence we made recommendations for practice and future research. Results Twenty-two studies were identified. Twelve studies evaluated message tailoring. In 10 of these studies, tailored messages resulted in greater physical activity than a control message. Six studies evaluated framed messages. Five of these studies demonstrated that gain-framed messages lead to stronger intentions to be active compared to a control message. Moreover, a gain-frame advantage was evident in three of the four studies that assessed physical activity. Four studies evaluated self-efficacy change messages. The two studies that used an experimental design provide a clear indication that individuals' beliefs can be affected by messages that incorporate types of information known to be determinants of self-efficacy. Overall, strong evidence to support definitive recommendations for optimal message content and structure was lacking. Conclusions Additional research testing the optimal content of messages used to supplement physical activity guidelines is needed. Tailored messages, gain-framed messages, and self-efficacy change messages hold promise as strategies for constructing physical activity messages and should be a focus of future research. PMID:20459779

  8. Seroprevalence of Dengue Fever in US Army Special Operations Forces: Initial Results and the Way Ahead.

    PubMed

    Caci, Jennifer B; Blaylock, Jason M; De La Barrera, Rafael; Griggs, April N; Lin, Leyi; Jarman, Richard G; Thomas, Stephen J; Lyons, Arthur G

    2014-01-01

    The endemicity of dengue fever (DF) and, consequently, sequelae of DF are increasing worldwide. The increases are largely a result of widespread international travel and the increased range of the mosquito vectors. US Army Special Operations Command (USASOC) personnel are at an increased risk of exposure to dengue based on their frequent deployments to and presence in dengue endemic areas worldwide. Repeated deployments to different endemic areas can increase the risk for developing the more serious sequelae of dengue: dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS). Information about the seroprevalence rate of dengue in USASOC personnel, in particular, is lacking and is critical to assessing the risk, tailoring preventive medicine countermeasures, leveraging field diagnostics, and maintaining mission capability. In the first part of a two-part project to assess baseline seroprevalence in USASOC units, a random, unit-stratified sample of 500 anonymous serum specimens from personnel assigned to the highest-risk units in USASOC were screened for dengue using a microneutralization assay. Of the 500 specimens screened, 56 (11.2%) of 500 had neutralizing titers (NT) (MN₅₀≥10) against at least one DENV serotype. Subsequent sample titration resulted in 48 (85.7%) of 56 of the samples with NT (MN₅₀≥10) against at least one dengue serotype for an overall dengue exposure rate of 9.6% (48 of 500). The second part of the ongoing project, started in 2012, was a multicenter, serosurveillance project using predeployment and postdeployment sera collected from USASOC personnel deployed to South and Central America, Africa, and Southeast Asia. Preliminary results show a 13.2% (55 of 414) seropositivity rate. The significance of these findings as they relate to personal risk and operational impact is discussed. 2014.

  9. Review: visual analytics of climate networks

    NASA Astrophysics Data System (ADS)

    Nocke, T.; Buschmann, S.; Donges, J. F.; Marwan, N.; Schulz, H.-J.; Tominski, C.

    2015-09-01

    Network analysis has become an important approach in studying complex spatiotemporal behaviour within geophysical observation and simulation data. This new field produces increasing numbers of large geo-referenced networks to be analysed. Particular focus lies currently on the network analysis of the complex statistical interrelationship structure within climatological fields. The standard procedure for such network analyses is the extraction of network measures in combination with static standard visualisation methods. Existing interactive visualisation methods and tools for geo-referenced network exploration are often either not known to the analyst or their potential is not fully exploited. To fill this gap, we illustrate how interactive visual analytics methods in combination with geovisualisation can be tailored for visual climate network investigation. Therefore, the paper provides a problem analysis relating the multiple visualisation challenges to a survey undertaken with network analysts from the research fields of climate and complex systems science. Then, as an overview for the interested practitioner, we review the state-of-the-art in climate network visualisation and provide an overview of existing tools. As a further contribution, we introduce the visual network analytics tools CGV and GTX, providing tailored solutions for climate network analysis, including alternative geographic projections, edge bundling, and 3-D network support. Using these tools, the paper illustrates the application potentials of visual analytics for climate networks based on several use cases including examples from global, regional, and multi-layered climate networks.

  10. Review: visual analytics of climate networks

    NASA Astrophysics Data System (ADS)

    Nocke, T.; Buschmann, S.; Donges, J. F.; Marwan, N.; Schulz, H.-J.; Tominski, C.

    2015-04-01

    Network analysis has become an important approach in studying complex spatiotemporal behaviour within geophysical observation and simulation data. This new field produces increasing amounts of large geo-referenced networks to be analysed. Particular focus lies currently on the network analysis of the complex statistical interrelationship structure within climatological fields. The standard procedure for such network analyses is the extraction of network measures in combination with static standard visualisation methods. Existing interactive visualisation methods and tools for geo-referenced network exploration are often either not known to the analyst or their potential is not fully exploited. To fill this gap, we illustrate how interactive visual analytics methods in combination with geovisualisation can be tailored for visual climate network investigation. Therefore, the paper provides a problem analysis, relating the multiple visualisation challenges with a survey undertaken with network analysts from the research fields of climate and complex systems science. Then, as an overview for the interested practitioner, we review the state-of-the-art in climate network visualisation and provide an overview of existing tools. As a further contribution, we introduce the visual network analytics tools CGV and GTX, providing tailored solutions for climate network analysis, including alternative geographic projections, edge bundling, and 3-D network support. Using these tools, the paper illustrates the application potentials of visual analytics for climate networks based on several use cases including examples from global, regional, and multi-layered climate networks.

  11. THE FIRST PUBLIC RELEASE OF SOUTH POLE TELESCOPE DATA: MAPS OF A 95 deg{sup 2} FIELD FROM 2008 OBSERVATIONS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Schaffer, K. K.; Crawford, T. M.; Benson, B. A.

    2011-12-10

    The South Pole Telescope (SPT) has nearly completed a 2500 deg{sup 2} survey of the southern sky in three frequency bands. Here, we present the first public release of SPT maps and associated data products. We present arcminute-resolution maps at 150 GHz and 220 GHz of an approximately 95 deg{sup 2} field centered at R.A. 82.{sup 0}7, decl. -55 Degree-Sign . The field was observed to a depth of approximately 17 {mu}K arcmin at 150 GHz and 41 {mu}K arcmin at 220 GHz during the 2008 austral winter season. Two variations on map filtering and map projection are presented, onemore » tailored for producing catalogs of galaxy clusters detected through their Sunyaev-Zel'dovich effect signature and one tailored for producing catalogs of emissive sources. We describe the data processing pipeline, and we present instrument response functions, filter transfer functions, and map noise properties. All data products described in this paper are available for download at http://pole.uchicago.edu/public/data/maps/ra5h30dec-55 and from the NASA Legacy Archive for Microwave Background Data Analysis server. This is the first step in the eventual release of data from the full 2500 deg{sup 2} SPT survey.« less

  12. Toward Switchable Photovoltaic Effect via Tailoring Mobile Oxygen Vacancies in Perovskite Oxide Films.

    PubMed

    Ge, Chen; Jin, Kui-Juan; Zhang, Qing-Hua; Du, Jian-Yu; Gu, Lin; Guo, Hai-Zhong; Yang, Jing-Ting; Gu, Jun-Xing; He, Meng; Xing, Jie; Wang, Can; Lu, Hui-Bin; Yang, Guo-Zhen

    2016-12-21

    The defect chemistry of perovskite oxides involves the cause to most of their abundant functional properties, including interface magnetism, charge transport, ionic exchange, and catalytic activity. The possibility to achieve dynamic control over oxygen anion vacancies offers a unique opportunity for the development of appealing switchable devices, which at present are commonly based on ferroelectric materials. Herein, we report the discovery of a switchable photovoltaic effect, that the sign of the open voltage and the short circuit current can be reversed by inverting the polarity of the applied field, upon electrically tailoring the distribution of oxygen vacancies in perovskite oxide films. This phenomenon is demonstrated in lateral photovoltaic devices based on both ferroelectric BiFeO 3 and paraelectric SrTiO 3 films, under a reversed applied field whose magnitude is much smaller than the coercivity value of BiFeO 3 . The migration of oxygen vacancies was directly observed by employing an advanced annular bright-field scanning transmission electron microscopy technique with in situ biasing equipment. We conclude that the band bending induced by the motion of oxygen vacancies is the driving force for the reversible switching between two photovoltaic states. The present work can provide an active path for the design of novel switchable photovoltaic devices with a wide range of transition metal oxides in terms of the ionic degrees of freedom.

  13. Imaging electric field dynamics with graphene optoelectronics.

    PubMed

    Horng, Jason; Balch, Halleh B; McGuire, Allister F; Tsai, Hsin-Zon; Forrester, Patrick R; Crommie, Michael F; Cui, Bianxiao; Wang, Feng

    2016-12-16

    The use of electric fields for signalling and control in liquids is widespread, spanning bioelectric activity in cells to electrical manipulation of microstructures in lab-on-a-chip devices. However, an appropriate tool to resolve the spatio-temporal distribution of electric fields over a large dynamic range has yet to be developed. Here we present a label-free method to image local electric fields in real time and under ambient conditions. Our technique combines the unique gate-variable optical transitions of graphene with a critically coupled planar waveguide platform that enables highly sensitive detection of local electric fields with a voltage sensitivity of a few microvolts, a spatial resolution of tens of micrometres and a frequency response over tens of kilohertz. Our imaging platform enables parallel detection of electric fields over a large field of view and can be tailored to broad applications spanning lab-on-a-chip device engineering to analysis of bioelectric phenomena.

  14. Countering Radicalization: Refocusing Responses to Violent Extremism Within the United States

    DTIC Science & Technology

    2011-12-01

    obsessed with religion.38 His initial goals were laudable; according to his brother, “He said he just wanted to do good. He wanted to go to heaven...time Samir arrived in North Carolina he was completely obsessed with extremist ideology. A friend, Adam Azad related that during their first...volunteer activities. Efforts can be tailored to specific areas such as university campuses, coffee shops, or community centers. Each effort

  15. Defense Acquisition Research Journal. Volume 21, Number 3, Issue 70

    DTIC Science & Technology

    2014-07-01

    the science of administration. New York, NY: Columbia University Institute of Public Administration. Hasik, J. (2004). Dream teams and brilliant eyes...advantage, the United States needs to develop a process that enables the lucid and rapid production of mission-tailored platforms that do not rely solely on...weapons does not require relying on the springboard of new technology, it just demands lucid and incisive thinking. However, this is not a strong point

  16. Building the Army: A Strategic Review of a Complex Problem

    DTIC Science & Technology

    2013-03-01

    is more than a true chameleon that slightly adapts its characteristics to the given case.”2 One cannot predict the shifting colors/characteristics...Strategy (NMS) of the United States of America calling for a flexible, agile, and adaptive Joint Force capable of full spectrum operations that...or may not be remedied, one can safely certify TAA as a robust and proven process based solely on the adaptable and tailorable Army that exists

  17. Structure: Suitable Staffing and Training of Functional Specialists within the United States Army Reserve Civil Affairs Force

    DTIC Science & Technology

    2011-12-01

    military organizations with capabilities to obtain simultaneous strategic and operational flexibility. This idea allows leaders to provide a tailor...that could provide immediate and proper treatment .119 A brief perspective of the 426th CA BN’s deployment in 2009 provides another example of CA...specialty areas. USAR civil affairs functional specialty cells train to provide expertise in political, military, economic, social, infrastructure, and

  18. Development of Smart Optical Gels with Highly Magnetically Responsive Bicelles.

    PubMed

    Isabettini, Stéphane; Stucki, Sandro; Massabni, Sarah; Baumgartner, Mirjam E; Reckey, Pernille Q; Kohlbrecher, Joachim; Ishikawa, Takashi; Windhab, Erich J; Fischer, Peter; Kuster, Simon

    2018-03-14

    Hydrogels delivering on-demand tailorable optical properties are formidable smart materials with promising perspectives in numerous fields, including the development of modern sensors and switches, the essential quality criterion being a defined and readily measured response to environmental changes. Lanthanide ion (Ln 3+ )-chelating bicelles are interesting building blocks for such materials because of their magnetic responsive nature. Imbedding these phospholipid-based nanodiscs in a magnetically aligned state in gelatin permits an orientation-dependent retardation of polarized light. The resulting tailorable anisotropy gives the gel a well-defined optical signature observed as a birefringence signal. These phenomena were only reported for a single bicelle-gelatin pair and required high magnetic field strengths of 8 T. Herein, we demonstrate the versatility and enhance the viability of this technology with a new generation of aminocholesterol (Chol-NH 2 )-doped bicelles imbedded in two different types of gelatin. The highly magnetically responsive nature of the bicelles allowed to gel the anisotropy at commercially viable magnetic field strengths between 1 and 3 T. Thermoreversible gels with a unique optical signature were generated by exposing the system to various temperature conditions and external magnetic field strengths. The resulting optical properties were a signature of the gel's environmental history, effectively acting as a sensor. Solutions containing the bicelles simultaneously aligning parallel and perpendicular to the magnetic field directions were obtained by mixing samples chelating Tm 3+ and Dy 3+ . These systems were successfully gelled, providing a material with two distinct temperature-dependent optical characteristics. The high degree of tunability in the magnetic response of the bicelles enables encryption of the gel's optical properties. The proposed gels are viable candidates for temperature tracking of sensitive goods and provide numerous perspectives for future development of tomorrow's smart materials and technologies.

  19. Rationale, design, and baseline findings from Seamos Saludables: a randomized controlled trial testing the efficacy of a culturally and linguistically adapted, computer- tailored physical activity intervention for Latinas

    PubMed Central

    Pekmezi, Dori; Dunsiger, Shira; Gans, Kim; Bock, Beth; Gaskins, Ronnesia; Marquez, Becky; Lee, Christina; Neighbors, Charles; Jennings, Ernestine; Tilkemeier, Peter; Marcus, Bess

    2012-01-01

    Background Latinos are now the largest (and fastest growing) ethnic minority group in the United States. Latinas report high rates of physical inactivity and suffer disproportionately from obesity, diabetes, and other conditions that are associated with sedentary lifestyles. Effective physical activity interventions are urgently needed to address these health disparities. Method/Design An ongoing randomized controlled trial will test the efficacy of a home-based, individually tailored physical activity print intervention for Latinas (1R01NR011295). This program was culturally and linguistically adapted for the target population through extensive formative research (6 focus groups, 25 cognitive interviews, iterative translation process). This participant feedback was used to inform intervention development. Then, 268 sedentary Latinas were randomly assigned to receive either the Tailored Intervention or the Wellness Contact Control arm. The intervention, based on Social Cognitive Theory and the Transtheoretical Model, consists of six months of regular mailings of motivation-matched physical activity manuals and tip sheets and individually tailored feedback reports generated by a computer expert system, followed by a tapered dose of mailings during the second six months (maintenance phase). The main outcome is change in minutes/week of physical activity at six months and one year as measured by the 7-Day Physical Activity Recall (7-Day PAR). To validate these findings, accelerometer data will be collected at the same time points. Discussion High reach, low cost, culturally relevant interventions to encourage physical activity among Latinas could help reduce health disparities and thus have a substantial positive impact on public health. PMID:22789455

  20. FPGA implementation of sparse matrix algorithm for information retrieval

    NASA Astrophysics Data System (ADS)

    Bojanic, Slobodan; Jevtic, Ruzica; Nieto-Taladriz, Octavio

    2005-06-01

    Information text data retrieval requires a tremendous amount of processing time because of the size of the data and the complexity of information retrieval algorithms. In this paper the solution to this problem is proposed via hardware supported information retrieval algorithms. Reconfigurable computing may adopt frequent hardware modifications through its tailorable hardware and exploits parallelism for a given application through reconfigurable and flexible hardware units. The degree of the parallelism can be tuned for data. In this work we implemented standard BLAS (basic linear algebra subprogram) sparse matrix algorithm named Compressed Sparse Row (CSR) that is showed to be more efficient in terms of storage space requirement and query-processing timing over the other sparse matrix algorithms for information retrieval application. Although inverted index algorithm is treated as the de facto standard for information retrieval for years, an alternative approach to store the index of text collection in a sparse matrix structure gains more attention. This approach performs query processing using sparse matrix-vector multiplication and due to parallelization achieves a substantial efficiency over the sequential inverted index. The parallel implementations of information retrieval kernel are presented in this work targeting the Virtex II Field Programmable Gate Arrays (FPGAs) board from Xilinx. A recent development in scientific applications is the use of FPGA to achieve high performance results. Computational results are compared to implementations on other platforms. The design achieves a high level of parallelism for the overall function while retaining highly optimised hardware within processing unit.

  1. Swagger or Humility or Swagger and Humility: A New Goal for Educating Students with Gifts and Talents

    ERIC Educational Resources Information Center

    Cross, Tracy L.

    2008-01-01

    It is believed by many that unsophisticated notions of elitism are the bane of the field of gifted education. Some claims of elitism are based on an interpretation of the founding of their country as inherently egalitarian. Educational opportunities that are tailored to student abilities are determined to be inherently elitist and therefore…

  2. Indexing in Art and Architecture: An Investigation and Analysis. Report to the Council on Library Resources.

    ERIC Educational Resources Information Center

    Crouch, Dora; And Others

    Funded by the Council on Library Resources, this project surveyed thesauri in the fields of art and architecture to seek out existing projects and analyze their content and form. It found that no comprehensive or standardized thesaurus presently exists for art and architecture; rather individual subjects are tailored to meet the needs of a…

  3. Fast optoelectric printing of plasmonic nanoparticles into tailored circuits

    NASA Astrophysics Data System (ADS)

    Rodrigo, José A.

    2017-04-01

    Plasmonic nanoparticles are able to control light at nanometre-scale by coupling electromagnetic fields to the oscillations of free electrons in metals. Deposition of such nanoparticles onto substrates with tailored patterns is essential, for example, in fabricating plasmonic structures for enhanced sensing. This work presents an innovative micro-patterning technique, based on optoelectic printing, for fast and straightforward fabrication of curve-shaped circuits of plasmonic nanoparticles deposited onto a transparent electrode often used in optoelectronics, liquid crystal displays, touch screens, etc. We experimentally demonstrate that this kind of plasmonic structure, printed by using silver nanoparticles of 40 nm, works as a plasmonic enhanced optical device allowing for polarized-color-tunable light scattering in the visible. These findings have potential applications in biosensing and fabrication of future optoelectronic devices combining the benefits of plasmonic sensing and the functionality of transparent electrodes.

  4. Tailored immune responses: novel effector helper T cell subsets in protective immunity.

    PubMed

    Kara, Ervin E; Comerford, Iain; Fenix, Kevin A; Bastow, Cameron R; Gregor, Carly E; McKenzie, Duncan R; McColl, Shaun R

    2014-02-01

    Differentiation of naïve CD4⁺ cells into functionally distinct effector helper T cell subsets, characterised by distinct "cytokine signatures," is a cardinal strategy employed by the mammalian immune system to efficiently deal with the rapidly evolving array of pathogenic microorganisms encountered by the host. Since the T(H)1/T(H)2 paradigm was first described by Mosmann and Coffman, research in the field of helper T cell biology has grown exponentially with seven functionally unique subsets having now been described. In this review, recent insights into the molecular mechanisms that govern differentiation and function of effector helper T cell subsets will be discussed in the context of microbial infections, with a focus on how these different helper T cell subsets orchestrate immune responses tailored to combat the nature of the pathogenic threat encountered.

  5. Tailoring plasmonic properties of nanobeam composites by the sliding disorder

    NASA Astrophysics Data System (ADS)

    Gric, Tatjana; Hess, Ortwin

    2017-11-01

    Nanobeam composites are important for designing sensing, nonlinear, and emission functionalities. Here, we describe a method for tuning the plasmonic properties of a silver nanobeam-based metamaterial. Such metamaterials open the wide avenues for a variety of applications in the fields of bio- and chemical sensing, nonlinearity enhancement, and fluorescence control. Specifically, we present the boundary between two nanobeam composites stacked together and exhibiting the sliding disorder. The modes are tunable. We simulated the solutions of surface plasmon polaritons (SPP) modes and their propagations. The configuration proposed here makes a breakthrough of the conventional configuration allowing for optimizations of SPP properties and making SPP application more flexible in practices. The wide plasmonic tuning range of nanobeam composites makes them promising in metamaterial-based optoelectronic devices. The plasma frequency is found to be tailored by the sliding disorder.

  6. The Role of Biomarkers in Detection of Cardio-toxicity.

    PubMed

    Shah, Kevin S; Yang, Eric H; Maisel, Alan S; Fonarow, Gregg C

    2017-06-01

    The goal of this paper is to review the current literature on the role of biomarkers in the detection and management of patients with cardio-oncologic disease. The role of biomarker surveillance in patients with known cardiac disease, as a result of chemotherapy or with the potential to develop cardio-toxicity, will be discussed. In addition, the studies surrounding sub-clinical cardiac toxicity monitoring during therapy, identification of high-risk patients prior to therapy, and tailoring oncologic therapies to potential biomarker risk profiles are reviewed. Based on evidence, to date, troponin and natriuretic peptides have the greatest potential to detect sub-clinical cardiac dysfunction and even tailor therapy to prevent progression based on biomarker profiles. Finally, future directions for potential utilization of novel biomarkers for the improvement of care of patients in the field of cardio-oncology are discussed.

  7. Excitation and tailoring of diffractive spin-wave beams in NiFe using nonuniform microwave antennas

    NASA Astrophysics Data System (ADS)

    Körner, H. S.; Stigloher, J.; Back, C. H.

    2017-09-01

    We experimentally demonstrate by time-resolved scanning magneto-optical Kerr microscopy the possibility to locally excite multiple spin-wave beams in the dipolar-dominated regime in metallic NiFe films. For this purpose we employ differently shaped nonuniform microwave antennas consisting of several coplanar waveguide sections different in size, thereby adapting an approach for the generation of spin-wave beams in the exchange-dominated regime suggested by Gruszecki et al. [Sci. Rep. 6, 22367 (2016), 10.1038/srep22367]. The occurring spin-wave beams are diffractive and we show that the width of the beam and its widening as it propagates can be tailored by the shape and the length of the nonuniformity. Moreover, the propagation direction of the diffractive beams can be manipulated by changing the bias field direction.

  8. Anisotropic field-of-view shapes for improved PROPELLER imaging☆

    PubMed Central

    Larson, Peder E.Z.; Lustig, Michael S.; Nishimura, Dwight G.

    2010-01-01

    The Periodically Rotated Overlapping ParallEL Lines with Enhanced Reconstruction (PROPELLER) method for magnetic resonance imaging data acquisition and reconstruction has the highly desirable property of being able to correct for motion during the scan, making it especially useful for imaging pediatric or uncooperative patients and diffusion imaging. This method nominally supports a circular field of view (FOV), but tailoring the FOV for noncircular shapes results in more efficient, shorter scans. This article presents new algorithms for tailoring PROPELLER acquisitions to the desired FOV shape and size that are flexible and precise. The FOV design also allows for rotational motion which provides better motion correction and reduced aliasing artifacts. Some possible FOV shapes demonstrated are ellipses, ovals and rectangles, and any convex, pi-symmetric shape can be designed. Standard PROPELLER reconstruction is used with minor modifications, and results with simulated motion presented confirm the effectiveness of the motion correction with these modified FOV shapes. These new acquisition design algorithms are simple and fast enough to be computed for each individual scan. Also presented are algorithms for further scan time reductions in PROPELLER echo-planar imaging (EPI) acquisitions by varying the sample spacing in two directions within each blade. PMID:18818039

  9. Robust active noise control in the loadmaster area of a military transport aircraft.

    PubMed

    Kochan, Kay; Sachau, Delf; Breitbach, Harald

    2011-05-01

    The active noise control (ANC) method is based on the superposition of a disturbance noise field with a second anti-noise field using loudspeakers and error microphones. This method can be used to reduce the noise level inside the cabin of a propeller aircraft. However, during the design process of the ANC system, extensive measurements of transfer functions are necessary to optimize the loudspeaker and microphone positions. Sometimes, the transducer positions have to be tailored according to the optimization results to achieve a sufficient noise reduction. The purpose of this paper is to introduce a controller design method for such narrow band ANC systems. The method can be seen as an extension of common transducer placement optimization procedures. In the presented method, individual weighting parameters for the loudspeakers and microphones are used. With this procedure, the tailoring of the transducer positions is replaced by adjustment of controller parameters. Moreover, the ANC system will be robust because of the fact that the uncertainties are considered during the optimization of the controller parameters. The paper describes the necessary theoretic background for the method and demonstrates the efficiency in an acoustical mock-up of a military transport aircraft.

  10. Black phosphorus nanodevices at terahertz frequencies: Photodetectors and future challenges

    NASA Astrophysics Data System (ADS)

    Viti, Leonardo; Politano, Antonio; Vitiello, Miriam Serena

    2017-03-01

    The discovery of graphene triggered a rapid rise of unexplored two-dimensional materials and heterostructures having optoelectronic and photonics properties that can be tailored on the nanoscale. Among these materials, black phosphorus (BP) has attracted a remarkable interest, thanks to many favorable properties, such as the high carrier mobility, the in-plane anisotropy, the possibility to alter its transport via electrical gating, and the direct band-gap, which can be tuned by thickness from 0.3 eV (bulk crystalline) to 1.7 eV (single atomic layer). When integrated in a microscopic field effect transistor, a few-layer BP flake can detect Terahertz (THz) frequency radiation. Remarkably, the in-plane crystalline anisotropy can be exploited to tailor the mechanisms that dominate the photoresponse; a BP-based field effect transistor can be engineered to act as a plasma-wave rectifier, a thermoelectric sensor, or a thermal bolometer. Here we present a review on recent research on BP detectors operating from 0.26 THz to 3.4 THz with particular emphasis on the underlying physical mechanisms and the future challenges that are yet to be addressed for making BP the active core of stable and reliable optical and electronic technologies.

  11. Computer-supported weight-based drug infusion concentrations in the neonatal intensive care unit.

    PubMed

    Giannone, Gay

    2005-01-01

    This article addresses the development of a computerized provider order entry (CPOE)-embedded solution for weight-based neonatal drug infusion developed during the transition from a legacy CPOE system to a customized application of a neonatal CPOE product during a hospital-wide information system transition. The importance of accurate fluid management in the neonate is reviewed. The process of tailoring the system that eventually resulted in the successful development of a computer application enabling weight-based medication infusion calculation for neonates within the CPOE information system is explored. In addition, the article provides guidelines on how to customize a vendor solution for hospitals with neonatal intensive care unit.

  12. Emergence of ferromagnetism in antiferromagnetic TbMnO3 by epitaxial strain

    NASA Astrophysics Data System (ADS)

    Marti, X.; Skumryev, V.; Ferrater, C.; García-Cuenca, M. V.; Varela, M.; Sánchez, F.; Fontcuberta, J.

    2010-05-01

    We show that in oxide thin films of spiral antiferromagnetic orthorhombic TbMnO3, ferromagnetism emerges resulting from epitaxially induced strain. The unit cell volume can be tuned (contracting up to a 2%) by varying thickness and deposition conditions; it is found that the ferromagnetic response correlates with the unit cell deformation. Such effect of strain on the magnetic properties turns out to be similar to that occurring in collinear orthorhombic antiferromagnets such as YMnO3. Owing to the intimate relationship between magnetic order and ferroelectricity in TbMnO3 these results may provide a new route to induce magnetoelectric coupling and tailor their ferroelectric response.

  13. Quality and productivity drive innovation and improvement at United Technologies Aerospace Operations, Inc.

    NASA Technical Reports Server (NTRS)

    Jamar, L. G.

    1986-01-01

    Quality and innovation are the hallmarks of the national space program. In programs that preceded the Shuttle Program the emphasis was on meeting the risks and technical challenges of space with safety, quality, reliability, and success. At United Technologies Aerospace Operations, Inc. (UTAO), the battle has developed along four primary fronts. These fronts include programs to motivate and reward people, development and construction of optimized processes and facilities, implementation of specifically tailored management systems, and the application of appropriate measurement and control systems. Each of these initiatives is described. However, to put this quality and productivity program in perspective, UTAO and its role in the Shuttle Program are described first.

  14. Benzocyclobutene (BCB) Polymer as Amphibious Buffer Layer for Graphene Field-Effect Transistor.

    PubMed

    Wu, Yun; Zou, Jianjun; Huo, Shuai; Lu, Haiyan; Kong, Yuecan; Chen, Tangshen; Wu, Wei; Xu, Jingxia

    2015-08-01

    Owing to the scattering and trapping effects, the interfaces of dielectric/graphene or substrate/graphene can tailor the performance of field-effect transistor (FET). In this letter, the polymer of benzocyclobutene (BCB) was used as an amphibious buffer layer and located at between the layers of substrate and graphene and between the layers of dielectric and graphene. Interestingly, with the help of nonpolar and hydrophobic BCB buffer layer, the large-scale top-gated, chemical vapor deposited (CVD) graphene transistors was prepared on Si/SiO2 substrate, its cutoff frequency (fT) and the maximum cutoff frequency (fmax) of the graphene field-effect transistor (GFET) can be reached at 12 GHz and 11 GHz, respectively.

  15. Towards an automated and efficient calculation of resonating vibrational states based on state-averaged multiconfigurational approaches

    NASA Astrophysics Data System (ADS)

    Meier, Patrick; Oschetzki, Dominik; Pfeiffer, Florian; Rauhut, Guntram

    2015-12-01

    Resonating vibrational states cannot consistently be described by single-reference vibrational self-consistent field methods but request the use of multiconfigurational approaches. Strategies are presented to accelerate vibrational multiconfiguration self-consistent field theory and subsequent multireference configuration interaction calculations in order to allow for routine calculations at this enhanced level of theory. State-averaged vibrational complete active space self-consistent field calculations using mode-specific and state-tailored active spaces were found to be very fast and superior to state-specific calculations or calculations with a uniform active space. Benchmark calculations are presented for trans-diazene and bromoform, which show strong resonances in their vibrational spectra.

  16. Towards an automated and efficient calculation of resonating vibrational states based on state-averaged multiconfigurational approaches

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Meier, Patrick; Oschetzki, Dominik; Pfeiffer, Florian

    Resonating vibrational states cannot consistently be described by single-reference vibrational self-consistent field methods but request the use of multiconfigurational approaches. Strategies are presented to accelerate vibrational multiconfiguration self-consistent field theory and subsequent multireference configuration interaction calculations in order to allow for routine calculations at this enhanced level of theory. State-averaged vibrational complete active space self-consistent field calculations using mode-specific and state-tailored active spaces were found to be very fast and superior to state-specific calculations or calculations with a uniform active space. Benchmark calculations are presented for trans-diazene and bromoform, which show strong resonances in their vibrational spectra.

  17. Energy density engineering via zero-admittance domains in all-dielectric stratified materials

    DOE PAGES

    Amra, Claude; Zerrad, Myriam; Lemarchand, Fabien; ...

    2018-02-12

    Emerging photonic, sensing, and quantum applications require high fields and tight localization but low power consumption. Spatial, spectral, and magnitude control of electromagnetic fields is of key importance for enabling experiments in atomic, molecular, and optical physics. Here in this paper, we introduce the concept of zero-admittance domains as a mechanism for tailoring giant optical fields bound within or on the surface of dielectric media. The described mechanism permits the creation of highly localized fields of extreme amplitudes simultaneously for incident photons of multiple wavelengths and incidence angles but arbitrary polarization states. No material constraints are placed upon the boundingmore » media. Both intrinsic and extrinsic potential practical limitations of the predicted field enhancement are analyzed and applications relevant to optical sensors and microsources are briefly discussed.« less

  18. Energy density engineering via zero-admittance domains in all-dielectric stratified materials

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Amra, Claude; Zerrad, Myriam; Lemarchand, Fabien

    Emerging photonic, sensing, and quantum applications require high fields and tight localization but low power consumption. Spatial, spectral, and magnitude control of electromagnetic fields is of key importance for enabling experiments in atomic, molecular, and optical physics. Here in this paper, we introduce the concept of zero-admittance domains as a mechanism for tailoring giant optical fields bound within or on the surface of dielectric media. The described mechanism permits the creation of highly localized fields of extreme amplitudes simultaneously for incident photons of multiple wavelengths and incidence angles but arbitrary polarization states. No material constraints are placed upon the boundingmore » media. Both intrinsic and extrinsic potential practical limitations of the predicted field enhancement are analyzed and applications relevant to optical sensors and microsources are briefly discussed.« less

  19. Simultaneous observation of the quantization and the interference pattern of a plasmonic near-field

    DOE PAGES

    Piazza, L.; Lummen, T. T. A.; Quiñonez, E.; ...

    2015-03-02

    Surface plasmon polaritons can confine electromagnetic fields in subwavelength spaces and are of interest for photonics, optical data storage devices and biosensing applications. In analogy to photons, they exhibit wave–particle duality, whose different aspects have recently been observed in separate tailored experiments. Here we demonstrate the ability of ultrafast transmission electron microscopy to simultaneously image both the spatial interference and the quantization of such confined plasmonic fields. Our experiments are accomplished by spatiotemporally overlapping electron and light pulses on a single nanowire suspended on a graphene film. The resulting energy exchange between single electrons and the quanta of the photoinducedmore » near-field is imaged synchronously with its spatial interference pattern. In conclusion, this methodology enables the control and visualization of plasmonic fields at the nanoscale, providing a promising tool for understanding the fundamental properties of confined electromagnetic fields and the development of advanced photonic circuits.« less

  20. Plasmonic superfocusing on metallic tips for near-field optical imaging and spectroscopy

    NASA Astrophysics Data System (ADS)

    Neacsu, Catalin C.; Olmon, Rob; Berweger, Samuel; Kappus, Alexandria; Kirchner, Friedrich; Ropers, Claus; Saraf, Lax; Raschke, Markus B.

    2008-03-01

    Realization of localized light sources through nonlocal excitation is important in the context of plasmon photonics, molecular sensing, and in particular near-field optical techniques. Here, the efficient conversion of propagating surface plasmons, launched on the shaft of a scanning probe tip, into localized plasmon at the apex provides a true nanoconfined light source. Focused ion beam milling is used to generate periodic surface nanostructures on the tip shaft that allow for tailoring the plasmon excitation. Using ultrashort visible and mid-IR transients the dynamics of the propagation and subsequent scattered emission is characterized. The strong field enhancement and spatial field confinement at the apex is demonstrated studying the coupling of the tip in near-field interaction with a flat sample surface. It is used in scattering near-field spectroscopic imaging (s-SNOM) to probe surface nanostructures with spatial resolution down to 10 nm.

  1. Quantum transport in graphene in presence of strain-induced pseudo-Landau levels

    NASA Astrophysics Data System (ADS)

    Settnes, Mikkel; Leconte, Nicolas; Barrios-Vargas, Jose E.; Jauho, Antti-Pekka; Roche, Stephan

    2016-09-01

    We report on mesoscopic transport fingerprints in disordered graphene caused by strain-field induced pseudomagnetic Landau levels (pLLs). Efficient numerical real space calculations of the Kubo formula are performed for an ordered network of nanobubbles in graphene, creating pseudomagnetic fields up to several hundreds of Tesla, values inaccessible by real magnetic fields. Strain-induced pLLs yield enhanced scattering effects across the energy spectrum resulting in lower mean free path and enhanced localization effects. In the vicinity of the zeroth order pLL, we demonstrate an anomalous transport regime, where the mean free paths increases with disorder. We attribute this puzzling behavior to the low-energy sub-lattice polarization induced by the zeroth order pLL, which is unique to pseudomagnetic fields preserving time-reversal symmetry. These results, combined with the experimental feasibility of reversible deformation fields, open the way to tailor a metal-insulator transition driven by pseudomagnetic fields.

  2. Control of the plasmonic near-field in metallic nanohelices.

    PubMed

    Caridad, José M; Winters, Sinéad; McCloskey, David; Duesberg, Georg S; Donegan, John F; Krstić, Vojislav

    2018-08-10

    The optical response of metallic nanohelices is mainly governed by a longitudinal localised surface plasmon resonance (LSPR) which arises due to the helical anisotropy of the system. Up to now, experimental studies have predominantly addressed the far-field response, despite the fact that the LSPR being of broad interest for converting incoming light into strongly enhanced (chiral) optical near-fields. Here, we demonstrate the control and spatial reproducibility of the plasmon-induced electromagnetic near-field around metallic nanohelices via surface-enhanced Raman scattering. We discuss how the near-field intensity of these nanostructures can be custom-tailored through both the nanoscaled helical structure and the electronic properties of the constituting metals. Our experiments, which employ graphene as an accurate probing material, are in quantitative agreement with corresponding numerical simulations. The findings demonstrate metallic nanohelices as reference nanostructured surfaces able to provide and fine-tune optical fields for fundamental studies as well as sensing or (chiro-optical) imaging applications.

  3. Simultaneous observation of the quantization and the interference pattern of a plasmonic near-field

    PubMed Central

    Piazza, L; Lummen, T.T.A.; Quiñonez, E; Murooka, Y; Reed, B.W.; Barwick, B; Carbone, F

    2015-01-01

    Surface plasmon polaritons can confine electromagnetic fields in subwavelength spaces and are of interest for photonics, optical data storage devices and biosensing applications. In analogy to photons, they exhibit wave–particle duality, whose different aspects have recently been observed in separate tailored experiments. Here we demonstrate the ability of ultrafast transmission electron microscopy to simultaneously image both the spatial interference and the quantization of such confined plasmonic fields. Our experiments are accomplished by spatiotemporally overlapping electron and light pulses on a single nanowire suspended on a graphene film. The resulting energy exchange between single electrons and the quanta of the photoinduced near-field is imaged synchronously with its spatial interference pattern. This methodology enables the control and visualization of plasmonic fields at the nanoscale, providing a promising tool for understanding the fundamental properties of confined electromagnetic fields and the development of advanced photonic circuits. PMID:25728197

  4. Tailored magnetic nanoparticles for optimizing magnetic fluid hyperthermia.

    PubMed

    Khandhar, Amit P; Ferguson, R Matthew; Simon, Julian A; Krishnan, Kannan M

    2012-03-01

    Magnetic Fluid Hyperthermia (MFH) is a promising approach towards adjuvant cancer therapy that is based on the localized heating of tumors using the relaxation losses of iron oxide magnetic nanoparticles (MNPs) in alternating magnetic fields (AMF). In this study, we demonstrate optimization of MFH by tailoring MNP size to an applied AMF frequency. Unlike conventional aqueous synthesis routes, we use organic synthesis routes that offer precise control over MNP size (diameter ∼10 to 25 nm), size distribution, and phase purity. Furthermore, the particles are successfully transferred to the aqueous phase using a biocompatible amphiphilic polymer, and demonstrate long-term shelf life. A rigorous characterization protocol ensures that the water-stable MNPs meet all the critical requirements: (1) uniform shape and monodispersity, (2) phase purity, (3) stable magnetic properties approaching that of the bulk, (4) colloidal stability, (5) substantial shelf life, and (6) pose no significant in vitro toxicity. Using a dedicated hyperthermia system, we then identified that 16 nm monodisperse MNPs (σ-0.175) respond optimally to our chosen AMF conditions (f = 373 kHz, H₀ = 14 kA/m); however, with a broader size distribution (σ-0.284) the Specific Loss Power (SLP) decreases by 30%. Finally, we show that these tailored MNPs demonstrate maximum hyperthermia efficiency by reducing viability of Jurkat cells in vitro, suggesting our optimization translates truthfully to cell populations. In summary, we present a way to intrinsically optimize MFH by tailoring the MNPs to any applied AMF, a required precursor to optimize dose and time of treatment. Copyright © 2011 Wiley Periodicals, Inc.

  5. Examining effectiveness of tailorable computer-assisted therapy programmes for substance misuse: Programme usage and clinical outcomes data from Breaking Free Online.

    PubMed

    Elison, Sarah; Jones, Andrew; Ward, Jonathan; Davies, Glyn; Dugdale, Stephanie

    2017-11-01

    When evaluating complex, tailorable digital behavioural interventions, additional approaches may be required alongside established methodologies such as randomised controlled trials (RCTs). Research evaluating a computer-assisted therapy (CAT) programme for substance misuse, Breaking Free Online (BFO), is informed by Medical Research Council (MRC) guidance recommending examination of 'mechanisms of action' of individual intervention strategies, which is relevant when evaluating digital interventions with content that may evolve over time. To report findings from examination of mechanisms of action of tailoring advice within the BFO programme and outcomes from specific intervention strategies. Analysis of covariance and linear regressions were used to assess intervention completion data, and psychometric and clinical outcomes, for 2311 service users accessing drug and alcohol treatment services across the UK. Tailoring advice provided to users appeared to prompt them to prioritise completion of intervention strategies associated with their areas of highest biopsychosocial impairment. Completion of specific intervention strategies within BFO were associated with specific clinical outcomes, with a dose response also being found. Mechanisms of action analyses revealed the primacy of cognitions, with cognitive restructuring strategies being associated with improvements in mental health, severity of substance dependence, quality of life and global biopsychosocial functioning. The MRC framework provides an evolved research paradigm within the field of digital behavioural change. By assessing baseline profiles of need, BFO can target the most appropriate clinical content for individual users. Mechanisms of action research can be used to inform modifications to BFO to continually update clinical content and the technology platform. Copyright © 2017 Elsevier Ltd. All rights reserved.

  6. Tailoring of EIA-649-1: Definition of Major (Class I) Engineering Change Proposal

    DTIC Science & Technology

    2015-05-15

    MISSILE SYSTEMS CENTER TAILORING TAILORING OF EIA -649-1: DEFINITION OF MAJOR (CLASS I) ENGINEERING CHANGE PROPOSAL APPROVED FOR...PUBLIC RELEASE; DISTRIBUTION IS UNLIMITED 1 Tailoring of EIA -649-1: Definition of Major (Class I) ECP. 1. Intent of this Tailoring Document...This tailoring document remedies a requirements gap in the industry consensus standard, EIA -649-1: 2015. Specifically, this tailoring provides a

  7. Fast electric control of the droplet size in a microfluidic T-junction droplet generator

    NASA Astrophysics Data System (ADS)

    Shojaeian, Mostafa; Hardt, Steffen

    2018-05-01

    The effect of DC electric fields on the generation of droplets of water and xanthan gum solutions in sunflower oil at a microfluidic T-junction is experimentally studied. The electric field leads to a significant reduction of the droplet diameter, by about a factor of 2 in the case of water droplets. The droplet size can be tuned by varying the electric field strength, an effect that can be employed to produce a stream of droplets with a tailor-made size sequence. Compared to the case of purely hydrodynamic droplet production without electric fields, the electric control has about the same effect on the droplet size if the electric stress at the liquid/liquid interface is the same as the hydrodynamic stress.

  8. Metaphotonics: An emerging field with opportunities and challenges

    NASA Astrophysics Data System (ADS)

    Baev, Alexander; Prasad, Paras N.; Ågren, Hans; Samoć, Marek; Wegener, Martin

    2015-09-01

    Metaphotonics is an emerging multidisciplinary field that deals with manipulation of electro-magnetic fields in nanoengineered (meta)materials using both electric and magnetic interactions and their cross-coupling. It offers unprecedented control of both linear and nonlinear optical functions for applications ranging from optical switching, to negative- and near-zero refractive index metamaterials, to chiral bioimaging, to cloaking. However, realization of such applications requires physics-guided nanoengineering of appropriate artificial media with electro-magnetic properties at visible and infrared wavelengths that are tailored to surpass those of any naturally-occurring material. Here, we review metaphotonics with a broadened vision and scope, introduce potential applications, describe the role of theoretical physics through multiscale modeling, review the materials development and current status, and outline opportunities in this fertile emerging field.

  9. A high-speed, reconfigurable, channel- and time-tagged photon arrival recording system for intensity-interferometry and quantum optics experiments

    NASA Astrophysics Data System (ADS)

    Girish, B. S.; Pandey, Deepak; Ramachandran, Hema

    2017-08-01

    We present a compact, inexpensive multichannel module, APODAS (Avalanche Photodiode Output Data Acquisition System), capable of detecting 0.8 billion photons per second and providing real-time recording on a computer hard-disk, of channel- and time-tagged information of the arrival of upto 0.4 billion photons per second. Built around a Virtex-5 Field Programmable Gate Array (FPGA) unit, APODAS offers a temporal resolution of 5 nanoseconds with zero deadtime in data acquisition, utilising an efficient scheme for time and channel tagging and employing Gigabit ethernet for the transfer of data. Analysis tools have been developed on a Linux platform for multi-fold coincidence studies and time-delayed intensity interferometry. As illustrative examples, the second-order intensity correlation function ( g 2) of light from two commonly used sources in quantum optics —a coherent laser source and a dilute atomic vapour emitting spontaneously, constituting a thermal source— are presented. With easy reconfigurability and with no restriction on the total record length, APODAS can be readily used for studies over various time scales. This is demonstrated by using APODAS to reveal Rabi oscillations on nanosecond time scales in the emission of ultracold atoms, on the one hand, and, on the other hand, to measure the second-order correlation function on the millisecond time scales from tailored light sources. The efficient and versatile performance of APODAS promises its utility in diverse fields, like quantum optics, quantum communication, nuclear physics, astrophysics and biology.

  10. Bringing mirrors to rest: grating concepts for ultra-precise interferometry

    NASA Astrophysics Data System (ADS)

    Kroker, Stefanie; Kley, Ernst-Bernhard; Tünnermann, Andreas

    2015-02-01

    Experiments in the field of high precision metrology such as the detection of gravitational waves are crucially limited by the thermal fluctuations of the optical components. In this contribution we present the current state of knowledge of high contrast gratings (HCGs) as low-noise elements for gravitational wave interferometers. We discuss how the properties of HCGs can be tailored such that beside highly reflective mirrors also diffractive beam splitters can be realized. Further, we show the impact of such gratings on the sensitivity of future gravitational wave detectors which can pave the way for the new field of gravitational wave astronomy.

  11. Nonassociative differential geometry and gravity with non-geometric fluxes

    NASA Astrophysics Data System (ADS)

    Aschieri, Paolo; Ćirić, Marija Dimitrijević; Szabo, Richard J.

    2018-02-01

    We systematically develop the metric aspects of nonassociative differential geometry tailored to the parabolic phase space model of constant locally non-geometric closed string vacua, and use it to construct preliminary steps towards a nonassociative theory of gravity on spacetime. We obtain explicit expressions for the torsion, curvature, Ricci tensor and Levi-Civita connection in nonassociative Riemannian geometry on phase space, and write down Einstein field equations. We apply this formalism to construct R-flux corrections to the Ricci tensor on spacetime, and comment on the potential implications of these structures in non-geometric string theory and double field theory.

  12. A class of invisible inhomogeneous media and the control of electromagnetic waves

    NASA Astrophysics Data System (ADS)

    Vial, B.; Liu, Y.; Horsley, S. A. R.; Philbin, T. G.; Hao, Y.

    2016-12-01

    We propose a general method to arbitrarily manipulate an electromagnetic wave propagating in a two-dimensional medium, without introducing any scattering. This leads to a whole class of isotropic spatially varying permittivity and permeability profiles that are invisible while shaping the field magnitude and/or phase. In addition, we propose a metamaterial structure working in the infrared that demonstrates deep subwavelength control of the electric field amplitude and strong reduction of the scattering. This work offers an alternative strategy to achieve invisibility with isotropic materials and paves the way for tailoring the propagation of light at the nanoscale.

  13. Danish Perioperative Nurses' Documentation: A Complex, Multifaceted Practice Connected With Unit Culture and Nursing Leadership.

    PubMed

    Søndergaard, Susanne F; Lorentzen, Vibeke; Sørensen, Erik E; Frederiksen, Kirsten

    2017-07-01

    Researchers have described the documentation practices of perioperative nurses as flawed and characterized by subjectivity and poor quality, which is often related to both the documentation tool and the nurses' level of commitment. Studies suggest that documentation of nursing care in the OR places special demands on electronic health records (EHRs). The purpose of this study was to explore how the use of an EHR tailored to perioperative practice affects Danish perioperative nurses' documentation practices. This study was a follow-up to a baseline study from 2014. For three months in the winter of 2015 to 2016, six participants tested an EHR containing a Danish edition of a selected section of the Perioperative Nursing Data Set. This study relied on realistic evaluation and participant observations to generate data. We found that nursing leadership was essential for improving perioperative nurses' documentation practices and that a tailored EHR may improve documentation practices. Copyright © 2017 AORN, Inc. Published by Elsevier Inc. All rights reserved.

  14. System engineering at the MEGARA project

    NASA Astrophysics Data System (ADS)

    Pérez-Calpena, A.; García-Vargas, María. Luisa; Gil de Paz, A.; Gallego Maestro, J.; Carrasco Licea, E.; Sánchez Moreno, F.; Iglesias-Páramo, J.

    2014-08-01

    MEGARA (Multi-Espectrógrafo en GTC de Alta Resolución para Astronomía) is a facility instrument of the 10.4m GTC (La Palma, Spain) working at optical wavelengths that provides both Integral-Field Unit (IFU) and Multi- Object Spectrograph (MOS) capabilities at resolutions in the range R=6,000-20,000. The MEGARA focal plane subsystems are located at one of the GTC focal stations, while the MEGARA refractive VPH based spectrograph is located at one of the Nasmyth platforms. The fiber bundles conduct the light from the focal plane subsystems to the pseudo-slits at the entrance of the spectrograph. The project is an initiative led by Universidad Complutense de Madrid (Spain) in collaboration with INAOE (Mexico), IAA-CSIC (Spain) and Universidad Politécnica de Madrid (Spain) and is developed under contract with GRANTECAN. The project is carried out by a multidisciplinary and geographically distributed team, which includes the in-kind contributions of the project partners and personnel from several private companies. The MEGARA system-engineering plan has been tailored to the project and is being applied to ensure the technical control of the project in order to finally meet the science high-level requirements and GTC constrains.

  15. Replication of Space-Shuttle Computers in FPGAs and ASICs

    NASA Technical Reports Server (NTRS)

    Ferguson, Roscoe C.

    2008-01-01

    A document discusses the replication of the functionality of the onboard space-shuttle general-purpose computers (GPCs) in field-programmable gate arrays (FPGAs) and application-specific integrated circuits (ASICs). The purpose of the replication effort is to enable utilization of proven space-shuttle flight software and software-development facilities to the extent possible during development of software for flight computers for a new generation of launch vehicles derived from the space shuttles. The replication involves specifying the instruction set of the central processing unit and the input/output processor (IOP) of the space-shuttle GPC in a hardware description language (HDL). The HDL is synthesized to form a "core" processor in an FPGA or, less preferably, in an ASIC. The core processor can be used to create a flight-control card to be inserted into a new avionics computer. The IOP of the GPC as implemented in the core processor could be designed to support data-bus protocols other than that of a multiplexer interface adapter (MIA) used in the space shuttle. Hence, a computer containing the core processor could be tailored to communicate via the space-shuttle GPC bus and/or one or more other buses.

  16. Superconductive coupling in tailored [(SnSe)1+δ ] m (NbSe2)1 multilayers

    NASA Astrophysics Data System (ADS)

    Trahms, Martina; Grosse, Corinna; Alemayehu, Matti B.; Hite, Omar K.; Chiatti, Olivio; Mogilatenko, Anna; Johnson, David C.; Fischer, Saskia F.

    2018-06-01

    Ferecrystals are a new artificially layered material system, in which the individual layers are stacked with monolayer precision and are turbostratically disordered. Here, the superconducting coupling of the NbSe2 layers in [(SnSe)1+δ ] m [NbSe2]1 ferecrystals with m between 1 and 6 are investigated. The variation of m effectively increases the distance between the superconducting NbSe2 monolayers. We find a systematic decrease of the transition temperature with an increasing number of SnSe layers per repeat unit. For m = 9 a superconducting transition can no longer be observed at temperatures above 250 mK. In order to investigate the superconducting coupling between individual NbSe2 layers, the cross-plane Ginzburg–Landau coherence lengths were determined. Electric transport measurements of the superconducting transition were performed in the presence of a magnetic field, oriented parallel and perpendicular to the layers, at temperatures closely below the transition temperature. A decoupling with increasing distance of the NbSe2 layers is observed. However, ferecrystals with NbSe2 layers separated by up to six layers of SnSe are still considered as three-dimensional superconductors.

  17. Control and near-field detection of surface plasmon interference patterns.

    PubMed

    Dvořák, Petr; Neuman, Tomáš; Břínek, Lukáš; Šamořil, Tomáš; Kalousek, Radek; Dub, Petr; Varga, Peter; Šikola, Tomáš

    2013-06-12

    The tailoring of electromagnetic near-field properties is the central task in the field of nanophotonics. In addition to 2D optics for optical nanocircuits, confined and enhanced electric fields are utilized in detection and sensing, photovoltaics, spatially localized spectroscopy (nanoimaging), as well as in nanolithography and nanomanipulation. For practical purposes, it is necessary to develop easy-to-use methods for controlling the electromagnetic near-field distribution. By imaging optical near-fields using a scanning near-field optical microscope, we demonstrate that surface plasmon polaritons propagating from slits along the metal-dielectric interface form tunable interference patterns. We present a simple way how to control the resulting interference patterns both by variation of the angle between two slits and, for a fixed slit geometry, by a proper combination of laser beam polarization and inhomogeneous far-field illumination of the structure. Thus the modulation period of interference patterns has become adjustable and new variable patterns consisting of stripelike and dotlike motifs have been achieved, respectively.

  18. Dynamic nuclear magnetic resonance field sensing with part-per-trillion resolution

    PubMed Central

    Gross, Simon; Barmet, Christoph; Dietrich, Benjamin E.; Brunner, David O.; Schmid, Thomas; Pruessmann, Klaas P.

    2016-01-01

    High-field magnets of up to tens of teslas in strength advance applications in physics, chemistry and the life sciences. However, progress in generating such high fields has not been matched by corresponding advances in magnetic field measurement. Based mostly on nuclear magnetic resonance, dynamic high-field magnetometry is currently limited to resolutions in the nanotesla range. Here we report a concerted approach involving tailored materials, magnetostatics and detection electronics to enhance the resolution of nuclear magnetic resonance sensing by three orders of magnitude. The relative sensitivity thus achieved amounts to 1 part per trillion (10−12). To exemplify this capability we demonstrate the direct detection and relaxometry of nuclear polarization and real-time recording of dynamic susceptibility effects related to human heart function. Enhanced high-field magnetometry will generally permit a fresh look at magnetic phenomena that scale with field strength. It also promises to facilitate the development and operation of high-field magnets. PMID:27910860

  19. Evaluating four gap-filling methods for eddy covariance measurements of evapotranspiration over hilly crop fields

    NASA Astrophysics Data System (ADS)

    Boudhina, Nissaf; Zitouna-Chebbi, Rim; Mekki, Insaf; Jacob, Frédéric; Ben Mechlia, Nétij; Masmoudi, Moncef; Prévot, Laurent

    2018-06-01

    Estimating evapotranspiration in hilly watersheds is paramount for managing water resources, especially in semiarid/subhumid regions. The eddy covariance (EC) technique allows continuous measurements of latent heat flux (LE). However, time series of EC measurements often experience large portions of missing data because of instrumental malfunctions or quality filtering. Existing gap-filling methods are questionable over hilly crop fields because of changes in airflow inclination and subsequent aerodynamic properties. We evaluated the performances of different gap-filling methods before and after tailoring to conditions of hilly crop fields. The tailoring consisted of splitting the LE time series beforehand on the basis of upslope and downslope winds. The experiment was setup within an agricultural hilly watershed in northeastern Tunisia. EC measurements were collected throughout the growth cycle of three wheat crops, two of them located in adjacent fields on opposite hillslopes, and the third one located in a flat field. We considered four gap-filling methods: the REddyProc method, the linear regression between LE and net radiation (Rn), the multi-linear regression of LE against the other energy fluxes, and the use of evaporative fraction (EF). Regardless of the method, the splitting of the LE time series did not impact the gap-filling rate, and it might improve the accuracies on LE retrievals in some cases. Regardless of the method, the obtained accuracies on LE estimates after gap filling were close to instrumental accuracies, and they were comparable to those reported in previous studies over flat and mountainous terrains. Overall, REddyProc was the most appropriate method, for both gap-filling rate and retrieval accuracy. Thus, it seems possible to conduct gap filling for LE time series collected over hilly crop fields, provided the LE time series are split beforehand on the basis of upslope-downslope winds. Future works should address consecutive vegetation growth cycles for a larger panel of conditions in terms of climate, vegetation, and water status.

  20. Static Aeroelasticity in Combat Aircraft.

    DTIC Science & Technology

    1986-01-01

    stiffness scaled beam machined along a predicted elastic axis, and load iola- tion cuts forward and aft of the beam, has proved to be most successful...aircraft components. Many papers deal with the activities in the field of structural optimization.’ 4sing fiber composites , a new design technique...Supersonic Design Composite Structures Fly - by - Wire Thin Profiles Aeroelastic Tailoring Unstable Aircraft V Variable Camber Lght Weight Pilot Handling

  1. Molecule nanoweaver

    DOEpatents

    Gerald, II; Rex, E [Brookfield, IL; Klingler, Robert J [Glenview, IL; Rathke, Jerome W [Homer Glen, IL; Diaz, Rocio [Chicago, IL; Vukovic, Lela [Westchester, IL

    2009-03-10

    A method, apparatus, and system for constructing uniform macroscopic films with tailored geometric assemblies of molecules on the nanometer scale. The method, apparatus, and system include providing starting molecules of selected character, applying one or more force fields to the molecules to cause them to order and condense with NMR spectra and images being used to monitor progress in creating the desired geometrical assembly and functionality of molecules that comprise the films.

  2. The Design of Industrial Arts Workshops for Secondary General Schools in the Asian Region. School Building Digest 13.

    ERIC Educational Resources Information Center

    Vickery, D. J.

    The curricula of industrial arts courses in the Asian Region are changing to a more general approach to arouse interest in, and simple understanding of, industry and industrial processes. Spaces for industrial arts should be less tightly tailored to the needs of specific subject fields than was the case in the past. In secondary general schools,…

  3. Mapping barriers and intervention activities to behaviour change theory for Mobilization of Vulnerable Elders in Ontario (MOVE ON), a multi-site implementation intervention in acute care hospitals.

    PubMed

    Moore, Julia E; Mascarenhas, Alekhya; Marquez, Christine; Almaawiy, Ummukulthum; Chan, Wai-Hin; D'Souza, Jennifer; Liu, Barbara; Straus, Sharon E

    2014-10-30

    As evidence-informed implementation interventions spread, they need to be tailored to address the unique needs of each setting, and this process should be well documented to facilitate replication. To facilitate the spread of the Mobilization of Vulnerable Elders in Ontario (MOVE ON) intervention, the aim of the current study is to develop a mapping guide that links identified barriers and intervention activities to behaviour change theory. Focus groups were conducted with front line health-care professionals to identify perceived barriers to implementation of an early mobilization intervention targeted to hospitalized older adults. Participating units then used or adapted intervention activities from an existing menu or developed new activities to facilitate early mobilization. A thematic analysis was performed on the focus group data, emphasizing concepts related to barriers to behaviour change. A behaviour change theory, the 'capability, opportunity, motivation-behaviour (COM-B) system', was used as a taxonomy to map the identified barriers to their root causes. We also mapped the behaviour constructs and intervention activities to overcome these. A total of 46 focus groups were conducted across 26 hospital inpatient units in Ontario, Canada, with 261 participants. The barriers were conceptualized at three levels: health-care provider (HCP), patient, and unit. Commonly mentioned barriers were time constraints and workload (HCP), patient clinical acuity and their perceived 'sick role' (patient), and lack of proper equipment and human resources (unit level). Thirty intervention activities to facilitate early mobilization of older adults were implemented across hospitals; examples of unit-developed intervention activities include the 'mobility clock' communication tool and the use of staff champions. A mapping guide was created with barriers and intervention activities matched though the lens of the COM-B system. We used a systematic approach to develop a guide, which maps barriers, intervention activities, and behaviour change constructs in order to tailor an implementation intervention to the local context. This approach allows implementers to identify potential strategies to overcome local-level barriers and to document adaptations.

  4. A review of combined experimental and computational procedures for assessing biopolymer structure–process–property relationships

    PubMed Central

    Gronau, Greta; Krishnaji, Sreevidhya T.; Kinahan, Michelle E.; Giesa, Tristan; Wong, Joyce Y.; Kaplan, David L.; Buehler, Markus J.

    2013-01-01

    Tailored biomaterials with tunable functional properties are desirable for many applications ranging from drug delivery to regenerative medicine. To improve the predictability of biopolymer materials functionality, multiple design parameters need to be considered, along with appropriate models. In this article we review the state of the art of synthesis and processing related to the design of biopolymers, with an emphasis on the integration of bottom-up computational modeling in the design process. We consider three prominent examples of well-studied biopolymer materials – elastin, silk, and collagen – and assess their hierarchical structure, intriguing functional properties and categorize existing approaches to study these materials. We find that an integrated design approach in which both experiments and computational modeling are used has rarely been applied for these materials due to difficulties in relating insights gained on different length- and time-scales. In this context, multiscale engineering offers a powerful means to accelerate the biomaterials design process for the development of tailored materials that suit the needs posed by the various applications. The combined use of experimental and computational tools has a very broad applicability not only in the field of biopolymers, but can be exploited to tailor the properties of other polymers and composite materials in general. PMID:22938765

  5. A review of combined experimental and computational procedures for assessing biopolymer structure-process-property relationships.

    PubMed

    Gronau, Greta; Krishnaji, Sreevidhya T; Kinahan, Michelle E; Giesa, Tristan; Wong, Joyce Y; Kaplan, David L; Buehler, Markus J

    2012-11-01

    Tailored biomaterials with tunable functional properties are desirable for many applications ranging from drug delivery to regenerative medicine. To improve the predictability of biopolymer materials functionality, multiple design parameters need to be considered, along with appropriate models. In this article we review the state of the art of synthesis and processing related to the design of biopolymers, with an emphasis on the integration of bottom-up computational modeling in the design process. We consider three prominent examples of well-studied biopolymer materials - elastin, silk, and collagen - and assess their hierarchical structure, intriguing functional properties and categorize existing approaches to study these materials. We find that an integrated design approach in which both experiments and computational modeling are used has rarely been applied for these materials due to difficulties in relating insights gained on different length- and time-scales. In this context, multiscale engineering offers a powerful means to accelerate the biomaterials design process for the development of tailored materials that suit the needs posed by the various applications. The combined use of experimental and computational tools has a very broad applicability not only in the field of biopolymers, but can be exploited to tailor the properties of other polymers and composite materials in general. Copyright © 2012 Elsevier Ltd. All rights reserved.

  6. Tailoring magnetic properties of Co nanocluster assembled films using hydrogen

    NASA Astrophysics Data System (ADS)

    Romero, C. P.; Volodin, A.; Paddubrouskaya, H.; Van Bael, M. J.; Van Haesendonck, C.; Lievens, P.

    2018-07-01

    Tailoring magnetic properties in nanocluster assembled cobalt (Co) thin films was achieved by admitting a small percentage of H2 gas (∼2%) into the Co gas phase cluster formation chamber prior to deposition. The oxygen content in the films is considerably reduced by the presence of hydrogen during the cluster formation, leading to enhanced magnetic interactions between clusters. Two sets of Co samples were fabricated, one without hydrogen gas and one with hydrogen gas. Magnetic properties of the non-hydrogenated and the hydrogen-treated Co nanocluster assembled films are comparatively studied using magnetic force microscopy and vibrating sample magnetometry. When comparing the two sets of samples the considerably larger coercive field of the H2-treated Co nanocluster film and the extended micrometer-sized magnetic domain structure confirm the enhancement of magnetic interactions between clusters. The thickness of the antiferromagnetic CoO layer is controlled with this procedure and modifies the exchange bias effect in these films. The exchange bias shift is lower for the H2-treated Co nanocluster film, which indicates that a thinner antiferromagnetic CoO reduces the coupling with the ferromagnetic Co. The hydrogen-treatment method can be used to tailor the oxidation levels thus controlling the magnetic properties of ferromagnetic cluster-assembled films.

  7. FWP executive summaries, Basic Energy Sciences Materials Sciences Programs (SNL/NM)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Samara, G.A.

    1997-05-01

    The BES Materials Sciences Program has the central theme of Scientifically Tailored Materials. The major objective of this program is to combine Sandia`s expertise and capabilities in the areas of solid state sciences, advanced atomic-level diagnostics and materials synthesis and processing science to produce new classes of tailored materials as well as to enhance the properties of existing materials for US energy applications and for critical defense needs. Current core research in this program includes the physics and chemistry of ceramics synthesis and processing, the use of energetic particles for the synthesis and study of materials, tailored surfaces and interfacesmore » for materials applications, chemical vapor deposition sciences, artificially-structured semiconductor materials science, advanced growth techniques for improved semiconductor structures, transport in unconventional solids, atomic-level science of interfacial adhesion, high-temperature superconductors, and the synthesis and processing of nano-size clusters for energy applications. In addition, the program includes the following three smaller efforts initiated in the past two years: (1) Wetting and Flow of Liquid Metals and Amorphous Ceramics at Solid Interfaces, (2) Field-Structured Anisotropic Composites, and (3) Composition-Modulated Semiconductor Structures for Photovoltaic and Optical Technologies. The latter is a joint effort with the National Renewable Energy Laboratory. Separate summaries are given of individual research areas.« less

  8. Tailored Emission Properties of ZnTe/ZnTe:O/ZnO Core-Shell Nanowires Coupled with an Al Plasmonic Bowtie Antenna Array.

    PubMed

    Nie, Kui-Ying; Tu, Xuecou; Li, Jing; Chen, Xuanhu; Ren, Fang-Fang; Zhang, Guo-Gang; Kang, Lin; Gu, Shulin; Zhang, Rong; Wu, Peiheng; Zheng, Youdou; Tan, Hark Hoe; Jagadish, Chennupati; Ye, Jiandong

    2018-06-14

    The ability to manipulate light-matter interaction in semiconducting nanostructures is fascinating for implementing functionalities in advanced optoelectronic devices. Here, we report the tailoring of radiative emissions in a ZnTe/ZnTe:O/ZnO core-shell single nanowire coupled with a one-dimensional aluminum bowtie antenna array. The plasmonic antenna enables changes in the excitation and emission processes, leading to an obvious enhancement of near band edge emission (2.2 eV) and subgap excitonic emission (1.7 eV) bound to intermediate band states in a ZnTe/ZnTe:O/ZnO core-shell nanowire as well as surface-enhanced Raman scattering at room temperature. The increase of emission decay rate in the nanowire/antenna system, probed by time-resolved photoluminescence spectroscopy, yields an observable enhancement of quantum efficiency induced by local surface plasmon resonance. Electromagnetic simulations agree well with the experimental observations, revealing a combined effect of enhanced electric near-field intensity and the improvement of quantum efficiency in the ZnTe/ZnTe:O/ZnO nanowire/antenna system. The capability of tailoring light-matter interaction in low-efficient emitters may provide an alternative platform for designing advanced optoelectronic and sensing devices with precisely controlled response.

  9. Optimization of laser-plasma injector via beam loading effects using ionization-induced injection

    NASA Astrophysics Data System (ADS)

    Lee, P.; Maynard, G.; Audet, T. L.; Cros, B.; Lehe, R.; Vay, J.-L.

    2018-05-01

    Simulations of ionization-induced injection in a laser driven plasma wakefield show that high-quality electron injectors in the 50-200 MeV range can be achieved in a gas cell with a tailored density profile. Using the PIC code Warp with parameters close to existing experimental conditions, we show that the concentration of N2 in a hydrogen plasma with a tailored density profile is an efficient parameter to tune electron beam properties through the control of the interplay between beam loading effects and varying accelerating field in the density profile. For a given laser plasma configuration, with moderate normalized laser amplitude, a0=1.6 and maximum electron plasma density, ne 0=4 ×1018 cm-3 , the optimum concentration results in a robust configuration to generate electrons at 150 MeV with a rms energy spread of 4% and a spectral charge density of 1.8 pC /MeV .

  10. Robustness of an artificially tailored fisheye imaging system with a curvilinear image surface

    NASA Astrophysics Data System (ADS)

    Lee, Gil Ju; Nam, Won Il; Song, Young Min

    2017-11-01

    Curved image sensors inspired by animal and insect eyes have provided a new development direction in next-generation digital cameras. It is known that natural fish eyes afford an extremely wide field of view (FOV) imaging due to the geometrical properties of the spherical lens and hemispherical retina. However, its inherent drawbacks, such as the low off-axis illumination and the fabrication difficulty of a 'dome-like' hemispherical imager, limit the development of bio-inspired wide FOV cameras. Here, a new type of fisheye imaging system is introduced that has simple lens configurations with a curvilinear image surface, while maintaining high off-axis illumination and a wide FOV. Moreover, through comparisons with commercial conventional fisheye designs, it is determined that the volume and required number of optical elements of the proposed design is practical while capturing the fundamental optical performances. Detailed design guidelines for tailoring the proposed optic system are also discussed.

  11. Demonstration of a terahertz pure vector beam by tailoring geometric phase.

    PubMed

    Wakayama, Toshitaka; Higashiguchi, Takeshi; Sakaue, Kazuyuki; Washio, Masakazu; Otani, Yukitoshi

    2018-06-06

    We demonstrate the creation of a vector beam by tailoring geometric phase of left- and right- circularly polarized beams. Such a vector beam with a uniform phase has not been demonstrated before because a vortex phase remains in the beam. We focus on vortex phase cancellation to generate vector beams in terahertz regions, and measure the geometric phase of the beam and its spatial distribution of polarization. We conduct proof-of-principle experiments for producing a vector beam with radial polarization and uniform phase at 0.36 THz. We determine the vortex phase of the vector beam to be below 4%, thus highlighting the extendibility and availability of the proposed concept to the super broadband spectral region from ultraviolet to terahertz. The extended range of our proposed techniques could lead to breakthroughs in the fields of microscopy, chiral nano-materials, and quantum information science.

  12. Clinical development of gene therapy needs a tailored approach: a regulatory perspective from the European Union.

    PubMed

    Narayanan, Gopalan; Cossu, Giulio; Galli, Maria Cristina; Flory, Egbert; Ovelgonne, Hans; Salmikangas, Paula; Schneider, Christian K; Trouvin, Jean-Hugues

    2014-03-01

    Gene therapy is a rapidly evolving field that needs an integrated approach, as acknowledged in the concept article on the revision of the guideline on gene transfer medicinal products. The first gene therapy application for marketing authorization was approved in the International Conference on Harmonisation (ICH) region in 2012, the product being Alipogene tiparvovec. The regulatory process for this product has been commented on extensively, highlighting the challenges posed by such a novel technology. Here, as current or previous members of the Committee for Advanced Therapies, we share our perspectives and views on gene therapy as a treatment modality based on current common understanding and regulatory experience of gene therapy products in the European Union to date. It is our view that a tailored approach is needed for a given gene therapy product in order to achieve successful marketing authorization.

  13. Bifunctional submicron colloidosomes coassembled from fluorescent and superparamagnetic nanoparticles.

    PubMed

    Bollhorst, Tobias; Shahabi, Shakiba; Wörz, Katharina; Petters, Charlotte; Dringen, Ralf; Maas, Michael; Rezwan, Kurosch

    2015-01-02

    Colloidosomes are microcapsules consisting of nanoparticle shells. These microcarriers can be self-assembled from a wide range of colloidal particles with selective chemical, physical, and morphological properties and show promise for application in the field of theranostic nanomedicine. Previous studies have mainly focused on fairly large colloidosomes (>1 μm) based on a single kind of particle; however, the intrinsic building-block nature of this microcarrier has not been exploited so far for the introduction of tailored functionality at the nanoscale. We report a synthetic route based on interfacial shear rheology studies that allows the simultaneous incorporation of different nanoparticles with distinct physical properties, that is, superparamagnetic iron oxide and fluorescent silica nanoparticles, in a single submicron colloidosome. These tailor-made microcapsules can potentially be used in various biomedical applications, including magnetic hyperthermia, magnetic particle imaging, drug targeting, and bioimaging. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  14. ICC Type II large-format FPA detector assemblies

    NASA Astrophysics Data System (ADS)

    Clynne, Thomas H.; Powers, Thomas P.

    1997-08-01

    ICC presents a new addition to their integrated detector assembly product line with the announcement of their type II large format staring class FPA units. A result of internally funded research and development, the ICC type II detector assembly can accommodate all existing large format staring class PtSi, InSb and MCT focal planes, up to 640 by 480. Proprietary methodologies completely eliminate all FPA stresses to allow for maximum FPA survivability. Standard optical and cryocooler interfaces allow for the use of BEI, AEG, TI SADA Hughes/Magnavox and Joule Thompson coolers. This unit has been qualified to the current SADA II thermal environmental specifications and was tailored around ICC's worldwide industry standard type IV product. Assembled in a real world flexible manufacturing environment, this unit features a wide degree of adaptability and can be easily modified to a user's specifications via standard options and add-ons that include optical interfaces, electrical interfaces and window/filter material selections.

  15. Multiple chiral topological states in liquid crystals from unstructured light beams

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Loussert, Charles; Brasselet, Etienne, E-mail: e.brasselet@loma.u-bordeaux1.fr

    2014-02-03

    It is shown experimentally that unstructured light beams can generate a wealth of distinct metastable defect structures in thin films of chiral liquid crystals. Various kinds of individual chiral topological states are obtained as well as dimers and trimers, which correspond to the entanglement of several topological unit cells. Self-assembled nested assemblies of several metastable particle-like topological states can also be formed. Finally, we propose and experimentally demonstrate an opto-electrical approach to generate tailor-made architectures.

  16. Cultural Changes Required in the Army to Truly Achieve a Total Force

    DTIC Science & Technology

    2016-02-16

    tailored to achieve anticipated objectives.”1 Honorable John M. McHugh , Secretary of the Army Army Directive 2012-08 (Army Total Force Policy...United States Soldier. 16 End Notes 1 McHugh , John M. “Army Directive 2012-08 (Army Total Force Policy).” Secretary of the Army, September 4...1 (February 2006): 40–42. McCullough, Amy. “Out of Reserve (Air Force Reserve Command)” 94, no. 12 (2011): 40. McHugh , John M. “Army Directive 2012

  17. Tailored Systems Architecture for Design of Space Science and Technology Missions Using DoDAF V2.0

    DTIC Science & Technology

    2009-12-01

    GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND...ADDRESS(ES) Air Force Institute of Technology,2950 Hobson Way,WPAFB,OH,45433-7765 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING...the focus on rapid development and transition, if a system architecture framework could be developed and used to increase visibility within the

  18. Tailored Systems Architecture for Design of Space Science and Technology Missions using DoDAF V2.0

    DTIC Science & Technology

    2009-12-01

    GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND...ADDRESS(ES) Air Force Institute of Technology,2950 Hobson Way,WPAFB,OH,45433-7765 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING...the focus on rapid development and transition, if a system architecture framework could be developed and used to increase visibility within the

  19. Invisible magnetic sensors

    NASA Astrophysics Data System (ADS)

    Mach-Batlle, Rosa; Navau, Carles; Sanchez, Alvaro

    2018-04-01

    Sensing magnetic fields is essential in many applications in biomedicine, transportation, or smart cities. The distortion magnetic sensors create in response to the field they are detecting may hinder their use, for example, in applications requiring dense packaging of sensors or accurately shaped field distributions. For sensing electromagnetic waves, cloaking shells that reduce the scattering of sensors have been introduced. However, the problem of making a magnetic sensor undetectable remains unsolved. Here, we present a general strategy on how to make a sensor magnetically invisible while keeping its ability to sense. The sensor is rendered undetectable by surrounding it with a spherical shell having a tailored magnetic permeability. Our method can be applied to arbitrary shaped magnetic sensors in arbitrary magnetic fields. The invisibility can be made exact when the sensor is spherical and the probed field is uniform. A metasurface composed of superconducting pieces is presented as a practical realization of the ideal invisibility shell.

  20. The cognitive style of nursing students: educational implications for teaching and learning.

    PubMed

    Noble, Kim A; Miller, Susan M; Heckman, James

    2008-06-01

    As cognitive and kinesthetic demands on nursing students increase, so does the need for optimal learning environments. Witkin's empirically supported measure of field dependent/independent cognitive style assesses the manner in which students perceive and process information and classifies them along a continuum of field dependence to field independence. Witkin's Groups Embedded Figures Test (GEFT) was administered to 876 students enrolled in 10 health care programs. Statistically significant differences in the GEFT mean scores of students enrolled in the different programs were discovered. The effect size was moderate. Undergraduate nursing students scored higher on the GEFT than did graduate or RN-to-BSN nursing students. However, nursing students were classified as more field dependent than students in other health-related disciplines. Due to their cognitive processing requirements, field-dependent nursing students may be at risk for academic failure. Therefore, instructional strategies tailored to students' needs should be incorporated into the nursing curriculum.

  1. Colloidal layers in magnetic fields and under shear flow

    NASA Astrophysics Data System (ADS)

    Löwen, H.; Messina, R.; Hoffmann, N.; Likos, C. N.; Eisenmann, C.; Keim, P.; Gasser, U.; Maret, G.; Goldberg, R.; Palberg, T.

    2005-11-01

    The behaviour of colloidal mono- and bilayers in external magnetic fields and under shear is discussed and recent progress is summarized. Superparamagnetic colloidal particles form monolayers when they are confined to a air-water interface in a hanging water droplet. An external magnetic field allows us to tune the strength of the mutual dipole-dipole interaction between the colloids and the anisotropy of the interaction can be controlled by the tilt angle of the magnetic field relative to the surface normal of the air-water interface. For sufficiently large magnetic field strength crystalline monolayers are found. The role of fluctuations in these two-dimensional crystals is discussed. Furthermore, clustering phenomena in binary mixtures of superparamagnetic particles forming fluid monolayers are predicted. Finally, we address sheared colloidal bilayers and find that the orientation of confined colloidal crystals can be tailored by a previously applied shear direction.

  2. Imaging electric field dynamics with graphene optoelectronics

    DOE PAGES

    Horng, Jason; Balch, Halleh B.; McGuire, Allister F.; ...

    2016-12-16

    The use of electric fields for signalling and control in liquids is widespread, spanning bioelectric activity in cells to electrical manipulation of microstructures in lab-on-a-chip devices. However, an appropriate tool to resolve the spatio-temporal distribution of electric fields over a large dynamic range has yet to be developed. Here we present a label-free method to image local electric fields in real time and under ambient conditions. Our technique combines the unique gate-variable optical transitions of graphene with a critically coupled planar waveguide platform that enables highly sensitive detection of local electric fields with a voltage sensitivity of a few microvolts,more » a spatial resolution of tens of micrometres and a frequency response over tens of kilohertz. Our imaging platform enables parallel detection of electric fields over a large field of view and can be tailored to broad applications spanning lab-on-a-chip device engineering to analysis of bioelectric phenomena.« less

  3. Imaging electric field dynamics with graphene optoelectronics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Horng, Jason; Balch, Halleh B.; McGuire, Allister F.

    The use of electric fields for signalling and control in liquids is widespread, spanning bioelectric activity in cells to electrical manipulation of microstructures in lab-on-a-chip devices. However, an appropriate tool to resolve the spatio-temporal distribution of electric fields over a large dynamic range has yet to be developed. Here we present a label-free method to image local electric fields in real time and under ambient conditions. Our technique combines the unique gate-variable optical transitions of graphene with a critically coupled planar waveguide platform that enables highly sensitive detection of local electric fields with a voltage sensitivity of a few microvolts,more » a spatial resolution of tens of micrometres and a frequency response over tens of kilohertz. Our imaging platform enables parallel detection of electric fields over a large field of view and can be tailored to broad applications spanning lab-on-a-chip device engineering to analysis of bioelectric phenomena.« less

  4. CORSICA modelling of ITER hybrid operation scenarios

    NASA Astrophysics Data System (ADS)

    Kim, S. H.; Bulmer, R. H.; Campbell, D. J.; Casper, T. A.; LoDestro, L. L.; Meyer, W. H.; Pearlstein, L. D.; Snipes, J. A.

    2016-12-01

    The hybrid operating mode observed in several tokamaks is characterized by further enhancement over the high plasma confinement (H-mode) associated with reduced magneto-hydro-dynamic (MHD) instabilities linked to a stationary flat safety factor (q ) profile in the core region. The proposed ITER hybrid operation is currently aiming at operating for a long burn duration (>1000 s) with a moderate fusion power multiplication factor, Q , of at least 5. This paper presents candidate ITER hybrid operation scenarios developed using a free-boundary transport modelling code, CORSICA, taking all relevant physics and engineering constraints into account. The ITER hybrid operation scenarios have been developed by tailoring the 15 MA baseline ITER inductive H-mode scenario. Accessible operation conditions for ITER hybrid operation and achievable range of plasma parameters have been investigated considering uncertainties on the plasma confinement and transport. ITER operation capability for avoiding the poloidal field coil current, field and force limits has been examined by applying different current ramp rates, flat-top plasma currents and densities, and pre-magnetization of the poloidal field coils. Various combinations of heating and current drive (H&CD) schemes have been applied to study several physics issues, such as the plasma current density profile tailoring, enhancement of the plasma energy confinement and fusion power generation. A parameterized edge pedestal model based on EPED1 added to the CORSICA code has been applied to hybrid operation scenarios. Finally, fully self-consistent free-boundary transport simulations have been performed to provide information on the poloidal field coil voltage demands and to study the controllability with the ITER controllers. Extended from Proc. 24th Int. Conf. on Fusion Energy (San Diego, 2012) IT/P1-13.

  5. Deep-subwavelength imaging of both electric and magnetic localized optical fields by plasmonic campanile nanoantenna

    DOE PAGES

    Caselli, Niccolò; La China, Federico; Bao, Wei; ...

    2015-06-05

    Tailoring the electromagnetic field at the nanoscale has led to artificial materials exhibiting fascinating optical properties unavailable in naturally occurring substances. Besides having fundamental implications for classical and quantum optics, nanoscale metamaterials provide a platform for developing disruptive novel technologies, in which a combination of both the electric and magnetic radiation field components at optical frequencies is relevant to engineer the light-matter interaction. Thus, an experimental investigation of the spatial distribution of the photonic states at the nanoscale for both field components is of crucial importance. Here we experimentally demonstrate a concomitant deep-subwavelength near-field imaging of the electric and magneticmore » intensities of the optical modes localized in a photonic crystal nanocavity. We take advantage of the “campanile tip”, a plasmonic near-field probe that efficiently combines broadband field enhancement with strong far-field to near-field coupling. In conclusion, by exploiting the electric and magnetic polarizability components of the campanile tip along with the perturbation imaging method, we are able to map in a single measurement both the electric and magnetic localized near-field distributions.« less

  6. Tailored nutritional guidance for home-dwelling AD families: the Feasibility of and Elements Promoting Positive Changes in Diet (NuAD-Trial).

    PubMed

    Puranen, T M; Pitkala, K H; Suominen, M H

    2015-04-01

    To describe the process and feasibility of our randomised, controlled intervention study (NuAD trial) that positively affected the nutrition and quality of life, and prevented falls of home-dwelling persons with Alzheimer disease (AD). This qualitative study comprised 40 persons with AD and spousal caregivers of our trial. Our intervention during one year involved tailored nutritional guidance for these couples. The nutritionist's field notes (about 100 pages) and the participant feedback questionnaires (N = 28) served to analyse the feasibility of intervention, factors promoting the application of intervention and challenges hindering it. Thematic content analysis served to analyse our data with the grounded theory approach. We identified several positive elements promoting better nutrition: positive attitudes on nutrition to participants including a participant-centred approach, positive feedback, findings of food diaries and practical suggestions. Home visits by the nutritionist were convenient and participants felt that someone cares. Group meetings which included protein-rich snacks strengthened the nutritional message by enabling discussions and socialising. The oral nutritional supplements (ONS) helped participants to regain their energy and to motivate them to exercise and make changes in their diets. Obstacles to making changes in diets included participants' false ideas about nutrition, especially with regard to weight gain. Health problems and functional limitations hampered food management, and some families had inveterate eating habits. The positive feedback from participants indicated the feasibility of our tailored nutritional guidance. Assessment-based, tailored nutritional guidance implemented with a personal and positive approach may inspire and empower AD families to make positive changes in their diets, leading them to improved nutrition and quality of life.

  7. Are we there yet? An examination of online tailored health communication.

    PubMed

    Suggs, L Suzanne; McIntyre, Chris

    2009-04-01

    Increasingly, the Internet is playing an important role in consumer health and patient-provider communication. Seventy-three percent of American adults are now online, and 79% have searched for health information on the Internet. This study provides a baseline understanding of the extent to which health consumers are able to find tailored communication online. It describes the current behavioral focus, the channels being used to deliver the tailored content, and the level of tailoring in online-tailored communication. A content analysis of 497 health Web sites found few examples of personalized, targeted, or tailored health sites freely available online. Tailored content was provided in 13 Web sites, although 15 collected individual data. More health risk assessment (HRA) sites included tailored feedback than other topics. The patterns that emerged from the analysis demonstrate that online health users can access a number of Web sites with communication tailored to their needs.

  8. Multifunctional shape and size specific magneto-polymer composite particles.

    PubMed

    Nunes, Janine; Herlihy, Kevin P; Mair, Lamar; Superfine, Richard; DeSimone, Joseph M

    2010-04-14

    Interest in uniform multifunctional magnetic particles is driven by potential applications in biomedical and materials science. Here we demonstrate the fabrication of highly tailored nanoscale and microscale magneto-polymer composite particles using a template based approach. Regiospecific surface functionalization of the particles was performed by chemical grafting and evaporative Pt deposition. Manipulation of the particles by an applied magnetic field was demonstrated in water and hydrogen peroxide.

  9. Building the Joint Battlespace Infosphere. Volume 2: Interactive Information Technologies

    DTIC Science & Technology

    1999-12-17

    G. A . Vouros, “ A Knowledge- Based Methodology for Supporting Multilingual and User -Tailored Interfaces ,” Interacting With Computers, Vol. 9 (1998), p...project is to develop a two-handed user interface to the stereoscopic field analyzer, an interactive 3-D scientific visualization system. The...62 See http://www.hitl.washington.edu/research/vrd/. 63 R. Baumann and R. Clavel, “Haptic Interface for Virtual Reality Based

  10. A situational analysis methodology to inform comprehensive HIV prevention and treatment programming, applied in rural South Africa.

    PubMed

    Treves-Kagan, Sarah; Naidoo, Evasen; Gilvydis, Jennifer M; Raphela, Elsie; Barnhart, Scott; Lippman, Sheri A

    2017-09-01

    Successful HIV prevention programming requires engaging communities in the planning process and responding to the social environmental factors that shape health and behaviour in a specific local context. We conducted two community-based situational analyses to inform a large, comprehensive HIV prevention programme in two rural districts of North West Province South Africa in 2012. The methodology includes: initial partnership building, goal setting and background research; 1 week of field work; in-field and subsequent data analysis; and community dissemination and programmatic incorporation of results. We describe the methodology and a case study of the approach in rural South Africa; assess if the methodology generated data with sufficient saturation, breadth and utility for programming purposes; and evaluate if this process successfully engaged the community. Between the two sites, 87 men and 105 women consented to in-depth interviews; 17 focus groups were conducted; and 13 health facilities and 7 NGOs were assessed. The methodology succeeded in quickly collecting high-quality data relevant to tailoring a comprehensive HIV programme and created a strong foundation for community engagement and integration with local health services. This methodology can be an accessible tool in guiding community engagement and tailoring future combination HIV prevention and care programmes.

  11. FEBio: finite elements for biomechanics.

    PubMed

    Maas, Steve A; Ellis, Benjamin J; Ateshian, Gerard A; Weiss, Jeffrey A

    2012-01-01

    In the field of computational biomechanics, investigators have primarily used commercial software that is neither geared toward biological applications nor sufficiently flexible to follow the latest developments in the field. This lack of a tailored software environment has hampered research progress, as well as dissemination of models and results. To address these issues, we developed the FEBio software suite (http://mrl.sci.utah.edu/software/febio), a nonlinear implicit finite element (FE) framework, designed specifically for analysis in computational solid biomechanics. This paper provides an overview of the theoretical basis of FEBio and its main features. FEBio offers modeling scenarios, constitutive models, and boundary conditions, which are relevant to numerous applications in biomechanics. The open-source FEBio software is written in C++, with particular attention to scalar and parallel performance on modern computer architectures. Software verification is a large part of the development and maintenance of FEBio, and to demonstrate the general approach, the description and results of several problems from the FEBio Verification Suite are presented and compared to analytical solutions or results from other established and verified FE codes. An additional simulation is described that illustrates the application of FEBio to a research problem in biomechanics. Together with the pre- and postprocessing software PREVIEW and POSTVIEW, FEBio provides a tailored solution for research and development in computational biomechanics.

  12. Rational design of Ag/TiO2 nanosystems by a combined RF-sputtering/sol-gel approach.

    PubMed

    Armelao, Lidia; Barreca, Davide; Bottaro, Gregorio; Gasparotto, Alberto; Maccato, Chiara; Tondello, Eugenio; Lebedev, Oleg I; Turner, Stuart; Van Tendeloo, Gustaaf; Sada, Cinzia; Stangar, Urska Lavrencic

    2009-12-21

    The present work is devoted to the preparation of Ag/TiO(2) nanosystems by an original synthetic strategy, based on the radio-frequency (RF) sputtering of silver particles on titania-based xerogels prepared by the sol-gel (SG) route. This approach takes advantage of the synergy between the microporous xerogel structure and the infiltration power characterizing RF-sputtering, whose combination enables the obtainment of a tailored dispersion of Ag-containing particles into the titania matrix. In addition, the system's chemico-physical features can be tuned further through proper ex situ thermal treatments in air at 400 and 600 degrees C. The synthesized composites are extensively characterized by the joint use of complementary techniques, that is, X-ray photoelectron and X-ray excited Auger electron spectroscopies (XPS, XE-AES), secondary ion mass spectrometry (SIMS), glancing incidence X-ray diffraction (GIXRD), field emission scanning electron microscopy (FE-SEM), transmission electron microscopy (TEM), electron diffraction (ED), high-angle annular dark field scanning TEM (HAADF-STEM), energy-filtered TEM (EF-TEM) and optical absorption spectroscopy. Finally, the photocatalytic performances of selected samples in the decomposition of the azo-dye Plasmocorinth B are preliminarily investigated. The obtained results highlight the possibility of tailoring the system characteristics over a broad range, directly influencing their eventual functional properties.

  13. User-Centered Design of Learn to Quit, a Smoking Cessation Smartphone App for People With Serious Mental Illness.

    PubMed

    Vilardaga, Roger; Rizo, Javier; Zeng, Emily; Kientz, Julie A; Ries, Richard; Otis, Chad; Hernandez, Kayla

    2018-01-16

    Smoking rates in the United States have been reduced in the past decades to 15% of the general population. However, up to 88% of people with psychiatric symptoms still smoke, leading to high rates of disease and mortality. Therefore, there is a great need to develop smoking cessation interventions that have adequate levels of usability and can reach this population. The objective of this study was to report the rationale, ideation, design, user research, and final specifications of a novel smoking cessation app for people with serious mental illness (SMI) that will be tested in a feasibility trial. We used a variety of user-centered design methods and materials to develop the tailored smoking cessation app. This included expert panel guidance, a set of design principles and theory-based smoking cessation content, development of personas and paper prototyping, usability testing of the app prototype, establishment of app's core vision and design specification, and collaboration with a software development company. We developed Learn to Quit, a smoking cessation app designed and tailored to individuals with SMI that incorporates the following: (1) evidence-based smoking cessation content from Acceptance and Commitment Therapy and US Clinical Practice Guidelines for smoking cessation aimed at providing skills for quitting while addressing mental health symptoms, (2) a set of behavioral principles to increase retention and comprehension of smoking cessation content, (3) a gamification component to encourage and sustain app engagement during a 14-day period, (4) an app structure and layout designed to minimize usability errors in people with SMI, and (5) a set of stories and visuals that communicate smoking cessation concepts and skills in simple terms. Despite its increasing importance, the design and development of mHealth technology is typically underreported, hampering scientific innovation. This report describes the systematic development of the first smoking cessation app tailored to people with SMI, a population with very high rates of nicotine addiction, and offers new design strategies to engage this population. mHealth developers in smoking cessation and related fields could benefit from a design strategy that capitalizes on the role visual engagement, storytelling, and the systematic application of behavior analytic principles to deliver evidence-based content. ©Roger Vilardaga, Javier Rizo, Emily Zeng, Julie A Kientz, Richard Ries, Chad Otis, Kayla Hernandez. Originally published in JMIR Serious Games (http://games.jmir.org), 16.01.2018.

  14. Tailored Testing Theory and Practice: A Basic Model, Normal Ogive Submodels, and Tailored Testing Algorithms

    DTIC Science & Technology

    1983-08-01

    ACCESSION NO «• TITLE (and Sublltle) TAILORED TESTING THEORY AND PRACTICE: A BASIC MODEL , NORMAL OGIVE SUBMODELS, AND TAILORED TESTING ALGORITHMS 7...single common-factor model , the author derives the two- and three-parametir normal ogfve il’^irTr^ functions as submodels. For both of these...PAOEfWiwi Dmia Bnfnd) NPRDC TR 83-32 AUGUST 1983 TAILORED TESTING THEORY AND PRACTICE: A BASIC MODEL , NORMAL OGIVE SUBMODELS, AND TAILORED TESTING

  15. Application of a macrocyclic compound, bambus[6]uril, in tailor-made liquid membranes for highly selective electromembrane extractions of inorganic anions.

    PubMed

    Šlampová, Andrea; Šindelář, Vladimír; Kubáň, Pavel

    2017-01-15

    A tailor-made liquid membrane consisting of a resistive organic solvent (nitrobenzene, NB) and a highly selective non-ionic macrocyclic compound (bambus[6]uril, BU6) was employed for electromembrane extraction (EME) of inorganic anions. BU6 facilitates strong host-guest interactions of its internal cavity with selected inorganic anions only and its presence in the liquid membrane ensured excellent selectivity of the EME process. EME transfers were directly related to association constants between BU6 and inorganic anions and nearly absolute selectivity was achieved for EMEs of iodide, bromide and perchlorate. Major inorganic anions (chloride, nitrate, sulphate and carbonate), which exhibit low interactions with BU6 cavity, were efficiently eliminated from the EME transfer. No interferences were observed for EMEs of target analytes from samples containing up to 100.000-fold higher concentrations of the major anions. Addition of species-specific macrocyclic modifiers to free and supported liquid membranes might thus open new directions in fine-tuning of EME selectivity. At optimized EME conditions (polypropylene hollow fiber impregnated with NB + 3% (w/w) BU6, extraction voltage 25 V, extraction time 15 min, deionized water as acceptor solution) perchlorate was selectively extracted from tap water at concentrations below the guideline value recommended by United States Environmental Protection Agency. Excellent selectivity of the tailor-made liquid membrane was further demonstrated by EME of bromide from sea water. Copyright © 2016 Elsevier B.V. All rights reserved.

  16. Mobile eHealth interventions for obesity: a timely opportunity to leverage convergence trends.

    PubMed

    Tufano, James T; Karras, Bryant T

    2005-12-20

    Obesity is often cited as the most prevalent chronic health condition and highest priority public health problem in the United States. There is a limited but growing body of evidence suggesting that mobile eHealth behavioral interventions, if properly designed, may be effective in promoting and sustaining successful weight loss and weight maintenance behavior changes. This paper reviews the current literature on the successes and failures of public health, provider-administered, and self-managed behavioral health interventions for weight loss. The prevailing theories of health behavior change are discussed from the perspective of how this knowledge can serve as an evidence base to inform the design of mobile eHealth weight loss interventions. Tailored informational interventions, which, in recent years, have proven to be the most effective form of conventional health behavior intervention for weight loss, are discussed. Lessons learned from the success of conventional tailored informational interventions and the early successes of desktop computer-assisted self-help weight management interventions are presented, as are design principles suggested by Social Cognitive Theory and the Social Marketing Model. Relevant computing and communications technology convergence trends are also discussed. The recent trends in rapid advancement, convergence, and public adoption of Web-enabled cellular telephone and wireless personal digital assistant (PDA) devices provide timely opportunities to deliver the mass customization capabilities, reach, and interactivity required for the development, administration, and adoption of effective population-level eHealth tailored informational interventions for obesity.

  17. Optimizing Nanoscale Quantitative Optical Imaging of Subfield Scattering Targets

    PubMed Central

    Henn, Mark-Alexander; Barnes, Bryan M.; Zhou, Hui; Sohn, Martin; Silver, Richard M.

    2016-01-01

    The full 3-D scattered field above finite sets of features has been shown to contain a continuum of spatial frequency information, and with novel optical microscopy techniques and electromagnetic modeling, deep-subwavelength geometrical parameters can be determined. Similarly, by using simulations, scattering geometries and experimental conditions can be established to tailor scattered fields that yield lower parametric uncertainties while decreasing the number of measurements and the area of such finite sets of features. Such optimized conditions are reported through quantitative optical imaging in 193 nm scatterfield microscopy using feature sets up to four times smaller in area than state-of-the-art critical dimension targets. PMID:27805660

  18. Towards an integrated AlGaAs waveguide platform for phase and polarisation shaping

    NASA Astrophysics Data System (ADS)

    Maltese, G.; Halioua, Y.; Lemaître, A.; Gomez-Carbonell, C.; Karimi, E.; Banzer, P.; Ducci, S.

    2018-05-01

    We propose, design and fabricate an on-chip AlGaAs waveguide capable of generating a controlled phase delay of π/2 between the guided transverse electric and magnetic modes. These modes possess significantly strong longitudinal field components as a direct consequence of their strong lateral confinement in the waveguide. We demonstrate that the effect of the device on a linearly polarised input beam is the generation of a field, which is circularly polarised in its transverse components and carries a phase vortex in its longitudinal component. We believe that the discussed integrated platform enables the generation of light beams with tailored phase and polarisation distributions.

  19. Material-independent modes for electromagnetic scattering

    NASA Astrophysics Data System (ADS)

    Forestiere, Carlo; Miano, Giovanni

    2016-11-01

    In this Rapid Communication, we introduce a representation of the electromagnetic field for the analysis and synthesis of the full-wave scattering by a homogeneous dielectric object of arbitrary shape in terms of a set of eigenmodes independent of its permittivity. The expansion coefficients are rational functions of the permittivity. This approach naturally highlights the role of plasmonic and photonic modes in any scattering process and suggests a straightforward methodology to design the permittivity of the object to pursue a prescribed tailoring of the scattered field. We discuss in depth the application of the proposed approach to the analysis and design of the scattering properties of a dielectric sphere.

  20. Molecular Imprinting: From Fundamentals to Applications

    NASA Astrophysics Data System (ADS)

    Komiyama, Makoto; Takeuchi, Toshifumi; Mukawa, Takashi; Asanuma, Hiroyuki

    2003-03-01

    Molecular imprinting, the polymerization of monomers in the presence of a template molecule which imprints structural information into the resulting polymers, is a scientific field which is rapidly gaining significance for a widening range of applications in biotechnology, biochemistry and pharmaceutical research. The methods and tools needed to distinguish target molecules from others by means of tailor-made receptors are constantly growing in importance and complexity. This book gives a concise and highly up-to-date overview of the remarkable progress made in this field in the last five years. The material is comprehensively presented by the authors, giving a thorough insight into fundamentals and applications for researchers in both industry and academy.

  1. Tailoring optical complex field with spiral blade plasmonic vortex lens

    PubMed Central

    Rui, Guanghao; Zhan, Qiwen; Cui, Yiping

    2015-01-01

    Optical complex fields have attracted increasing interests because of the novel effects and phenomena arising from the spatially inhomogeneous state of polarizations and optical singularities of the light beam. In this work, we propose a spiral blade plasmonic vortex lens (SBPVL) that offers unique opportunities to manipulate these novel fields. The strong interaction between the SBPVL and the optical complex fields enable the synthesis of highly tunable plasmonic vortex. Through theoretical derivations and numerical simulations we demonstrated that the characteristics of the plasmonic vortex are determined by the angular momentum (AM) of the light, and the geometrical topological charge of the SBPVL, which is govern by the nonlinear superposition of the pitch and the number of blade element. In addition, it is also shown that by adjusting the geometric parameters, SBPVL can be utilized to focus and manipulate optical complex field with fractional AM. This miniature plasmonic device may find potential applications in optical trapping, optical data storage and many other related fields. PMID:26335894

  2. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Imani, Mohammadreza F., E-mail: mohamad.imani@gmail.com; Grbic, Anthony

    One of the obstacles preventing wireless power transfer from becoming ubiquitous is their leakage of power: high-amplitude electromagnetic fields that can interfere with other electronic devices, increase health concerns, or hinder power metering. In this paper, we present near-field plates (NFPs) as a novel method to tailor the electromagnetic fields generated by a wireless power transfer system while maintaining high efficiency. NFPs are modulated arrays or surfaces designed to form prescribed near-field patterns. The NFP proposed in this paper consists of an array of loaded loops that are designed to confine the electromagnetic fields of a resonant transmitting loop tomore » the desired direction (receiving loop) while suppressing fields in other directions. The step-by-step design procedure for this device is outlined. Two NFPs are designed and examined in full-wave simulation. Their performance is shown to be in close agreement with the design predictions, thereby verifying the proposed design and operation. A NFP is also fabricated and experimentally shown to form a unidirectional wireless power transfer link with high efficiency.« less

  3. Identifying determinants of care for tailoring implementation in chronic diseases: an evaluation of different methods.

    PubMed

    Krause, Jane; Van Lieshout, Jan; Klomp, Rien; Huntink, Elke; Aakhus, Eivind; Flottorp, Signe; Jaeger, Cornelia; Steinhaeuser, Jost; Godycki-Cwirko, Maciek; Kowalczyk, Anna; Agarwal, Shona; Wensing, Michel; Baker, Richard

    2014-08-12

    The tailoring of implementation interventions includes the identification of the determinants of, or barriers to, healthcare practice. Different methods for identifying determinants have been used in implementation projects, but which methods are most appropriate to use is unknown. The study was undertaken in five European countries, recommendations for a different chronic condition being addressed in each country: Germany (polypharmacy in multimorbid patients); the Netherlands (cardiovascular risk management); Norway (depression in the elderly); Poland (chronic obstructive pulmonary disease--COPD); and the United Kingdom (UK) (obesity). Using samples of professionals and patients in each country, three methods were compared directly: brainstorming amongst health professionals, interviews of health professionals, and interviews of patients. The additional value of discussion structured through reference to a checklist of determinants in addition to brainstorming, and determinants identified by open questions in a questionnaire survey, were investigated separately. The questionnaire, which included closed questions derived from a checklist of determinants, was administered to samples of health professionals in each country. Determinants were classified according to whether it was likely that they would inform the design of an implementation intervention (defined as plausibly important determinants). A total of 601 determinants judged to be plausibly important were identified. An additional 609 determinants were judged to be unlikely to inform an implementation intervention, and were classified as not plausibly important. Brainstorming identified 194 of the plausibly important determinants, health professional interviews 152, patient interviews 63, and open questions 48. Structured group discussion identified 144 plausibly important determinants in addition to those already identified by brainstorming. Systematic methods can lead to the identification of large numbers of determinants. Tailoring will usually include a process to decide, from all the determinants that are identified, those to be addressed by implementation interventions. There is no best buy of methods to identify determinants, and a combination should be used, depending on the topic and setting. Brainstorming is a simple, low cost method that could be relevant to many tailored implementation projects.

  4. Using social media to deliver weight loss programming to young adults: Design and rationale for the Healthy Body Healthy U (HBHU) trial.

    PubMed

    Napolitano, Melissa A; Whiteley, Jessica A; Mavredes, Meghan N; Faro, Jamie; DiPietro, Loretta; Hayman, Laura L; Neighbors, Charles J; Simmens, Samuel

    2017-09-01

    The transitional period from late adolescence to early adulthood is a vulnerable period for weight gain, with a twofold increase in overweight/obesity during this life transition. In the United States, approximately one-third of young adults have obesity and are at a high risk for weight gain. To describe the design and rationale of a National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) sponsored randomized, controlled clinical trial, the Healthy Body Healthy U (HBHU) study, which compares the differential efficacy of three interventions on weight loss among young adults aged 18-35years. The intervention is delivered via Facebook and SMS Text Messaging (text messaging) and includes: 1) targeted content (Targeted); 2) tailored or personalized feedback (Tailored); or 3) contact control (Control). Recruitment is on-going at two campus sites, with the intervention delivery conducted by the parent site. A total of 450 students will be randomly-assigned to receive one of three programs for 18months. We hypothesize that: a) the Tailored group will lose significantly more weight at the 6, 12, 18month follow-ups compared with the Targeted group; and that b) both the Tailored and Targeted groups will have greater weight loss at the 6, 12, 18month follow-ups than the Control group. We also hypothesize that participants who achieve a 5% weight loss at 6 and 18months will have greater improvements in their cardiometabolic risk factors than those who do not achieve this target. We will examine intervention costs to inform implementation and sustainability other universities. Expected study completion date is 2019. This project has significant public health impact, as the successful translation could reach as many as 20 million university students each year, and change the current standard of practice for promoting weight management within university campus communities. ClinicalTrial.gov: NCT02342912. Copyright © 2017. Published by Elsevier Inc.

  5. Building policy-making capacity in the Ministry of Health: the Kazakhstan experience.

    PubMed

    Chanturidze, Tata; Adams, Orvill; Tokezhanov, Bolat; Naylor, Mike; Richardson, Erica

    2015-01-20

    Recent economic growth in Kazakhstan has been accompanied by slower improvements in population health and this has renewed impetus for health system reform. Strengthening strategic planning and policy-making capacity in the Ministry of Health has been identified as an important priority, particularly as the Ministry of Health is leading the health system reform process. The intervention was informed by the United Nations Development Programme (UNDP) framework for capacity building which views capacity building as an ongoing process embedded in local institutions and practices. In response to local needs extra elements were included in the framework to tailor the capacity building programme according to the existing policy and budget cycles and respective competence requirements, and link it with transparent career development structures of the Ministry of Health. This aspect of the programme was informed by the institutional capability assessment model used by the United Kingdom National Health Service (NHS) which was adapted to examine the specific organizational and individual competences of the Ministry of Health in Kazakhstan. There were clear successes in building capacity for policy making and strategic planning within the Ministry of Health in Kazakhstan, including better planned, more timely and in-depth responses to policy assignments. Embedding career development as a part of this process was more challenging. This case study highlights the importance of strong political will and high level support for capacity building in ensuring the sustainability of programmes. It also shows that capacity-building programmes need to ensure full engagement with all local stakeholders, or where this is not possible, programmes need to be targeted narrowly to those stakeholders who will benefit most, for the greatest impact to be achieved. In sum, high quality tailor-made capacity development programmes should be based on thorough needs assessment of individual and organizational competences in a specific institutional setting. The experience showed that complementary approaches to human resource development worked effectively in the context of organizations and systems, where an enabling environment was present, and country ownership and political will was complemented by strong technical assistance to design and deliver high quality tailor-made capacity building initiatives.

  6. Neural correlates of message tailoring and self-relatedness in smoking cessation programming.

    PubMed

    Chua, Hannah Faye; Liberzon, Israel; Welsh, Robert C; Strecher, Victor J

    2009-01-15

    Smoking leads to illnesses including addiction, cancer, and cardiovascular and respiratory diseases. Different intervention programs have become available. In the past decade, providing tailored smoking cessation messages has been shown to be more effective in inducing smoking cessation than one-size-fits-all interventions. However, little is known about the brain responses of smokers when they receive tailored smoking cessation messages. A neuroimaging study using blocked and event-related designs examined neural activity in 24 smokers exposed to high-tailored and low-tailored smoking cessation messages. In both blocked and event-related conditions, rostral medial prefrontal cortex and precuneus/posterior cingulate were engaged more during the processing of high-tailored smoking cessation messages than low-tailored smoking cessation messages. The activation patterns of smokers to tailored cessation messages show involvement of brain areas commonly implicated in self-related processing. Results seem to add support to the suggested role of self-relevance in tailored cessation programs, where previous studies have shown a potential mediating role of self-relevance on smoking abstinence. The findings are relevant to understanding the cognitive mechanisms underlying tailored message processing and might point to new directions for testing response to health communications programming.

  7. Neural correlates of message tailoring and self-relatedness in smoking cessation programming

    PubMed Central

    Chua, Hannah Faye; Liberzon, Israel; Welsh, Robert C.; Strecher, Victor J.

    2011-01-01

    BACKGROUND Smoking leads to illnesses including addiction, cancer, and cardiovascular and respiratory diseases. Different intervention programs have become available. In the past decade, providing tailored smoking cessation messages has been shown to be more effective in inducing smoking cessation than one-size-fits-all interventions. However, little is known about the brain responses of smokers when they receive tailored smoking cessation messages. METHODS A neuroimaging study using blocked and event-related designs examined neural activity in 24 smokers exposed to high-tailored and low-tailored smoking cessation messages. RESULTS: In both blocked and event-related conditions, rostral medial prefrontal cortex and precuneus/posterior cingulate were engaged more during the processing of high-tailored smoking cessation messages than low-tailored smoking cessation messages. CONCLUSION The activation patterns of smokers to tailored cessation messages show involvement of brain areas commonly implicated in self-related processing. Results seem to add support to the suggested role of self-relevance in tailored cessation programs, where previous studies have shown a potential mediating role of self-relevance on smoking abstinence. The findings are relevant to understanding the cognitive mechanisms underlying tailored message processing and may point to new directions for testing response to health communications programming. PMID:18926523

  8. Randomized controlled trial of a web-based computer-tailored smoking cessation program as a supplement to nicotine patch therapy.

    PubMed

    Strecher, Victor J; Shiffman, Saul; West, Robert

    2005-05-01

    To assess the efficacy of World Wide Web-based tailored behavioral smoking cessation materials among nicotine patch users. Two-group randomized controlled trial. World Wide Web in England and Republic of Ireland. A total of 3971 subjects who purchased a particular brand of nicotine patch and logged-on to use a free web-based behavioral support program. Web-based tailored behavioral smoking cessation materials or web-based non-tailored materials. Twenty-eight-day continuous abstinence rates were assessed by internet-based survey at 6-week follow-up and 10-week continuous rates at 12-week follow-up. Using three approaches to the analyses of 6- and 12-week outcomes, participants in the tailored condition reported clinically and statistically significantly higher continuous abstinence rates than participants in the non-tailored condition. In our primary analyses using as a denominator all subjects who logged-on to the treatment site at least once, continuous abstinence rates at 6 weeks were 29.0% in the tailored condition versus 23.9% in the non-tailored condition (OR = 1.30; P = 0.0006); at 12 weeks continuous abstinence rates were 22.8% versus 18.1%, respectively (OR = 1.34; P = 0.0006). Moreover, satisfaction with the program was significantly higher in the tailored than in the non-tailored condition. The results of this study demonstrate a benefit of the web-based tailored behavioral support materials used in conjunction with nicotine replacement therapy. A web-based program that collects relevant information from users and tailors the intervention to their specific needs had significant advantages over a web-based non-tailored cessation program.

  9. Measurement of rolling friction by a damped oscillator

    NASA Technical Reports Server (NTRS)

    Dayan, M.; Buckley, D. H.

    1983-01-01

    An experimental method for measuring rolling friction is proposed. The method is mechanically simple. It is based on an oscillator in a uniform magnetic field and does not involve any mechanical forces except for the measured friction. The measured pickup voltage is Fourier analyzed and yields the friction spectral response. The proposed experiment is not tailored for a particular case. Instead, various modes of operation, suitable to different experimental conditions, are discussed.

  10. Phase behavior of ternary polymer brushes

    DOE PAGES

    Simocko, Chester K.; Frischknecht, Amalie L.; Huber, Dale L.

    2016-01-07

    Ternary polymer brushes consisting of polystyrene, poly(methyl methacrylate), and poly(4-vinylpyridine) have been synthesized. These brushes laterally phase separate into several distinct phases and can be tailored by altering the relative polymer composition. Self-consistent field theory has been used to predict the phase diagram and model both the horizontal and vertical phase behavior of the polymer brushes. As a result, all phase behaviors observed experimentally correlate well with the theoretical model.

  11. Morphological and physical - chemical issues of metal nanostructures used in medical field

    NASA Astrophysics Data System (ADS)

    Duceac, L. D.; Velenciuc, N.; Dobre, E. C.

    2016-06-01

    In recent years applications of nanotechnology integrated into nanomedicine and bio-nanotechnology have attracted the attention of many researchers from different fields. Processes from chemical engineering especially nanostructured materials play an important role in medical and pharmaceutical development. Fundamental researches focused on finding simple, easily accomplished synthesis methods, morphological aspects and physico-chemical advanced characterization of nanomaterials. More over, by controlling synthesis conditions textural characteristics and physicochemical properties such as particle size, shape, surface, porosity, aggregation degree and composition can be tailored. Low cytotoxicity and antimicrobial effects of these nanostructured materials makes them be applied in medicine field. The major advantage of metal based nanoparticles is the use either for their antimicrobial properties or as drug-carriers having the potential to be active at low concentrations against infectious agents.

  12. Observation of end-vortex nucleation in individual ferromagnetic nanotubes

    NASA Astrophysics Data System (ADS)

    Mehlin, A.; Gross, B.; Wyss, M.; Schefer, T.; Tütüncüoglu, G.; Heimbach, F.; Fontcuberta i Morral, A.; Grundler, D.; Poggio, M.

    2018-04-01

    The reversal of uniform axial magnetization in a ferromagnetic nanotube (FNT) has been predicted to occur through the nucleation and propagation of vortex domains forming at the ends. We provide experimental evidence for this behavior through dynamic cantilever magnetometry measurements of individual FNTs. In particular, we identify the nucleation of the vortex end domains as a function of applied magnetic field and show that they mark the onset of magnetization reversal. We find that the nucleation field depends sensitively on the angle between the end surface of the FNT and the applied field. Micromagnetic simulations substantiate the experimental results and highlight the importance of the ends in determining the reversal process. The control over end-vortex nucleation enabled by our findings is promising for the production of FNTs with tailored reversal properties.

  13. Earth field NMR with chemical shift spectral resolution: theory and proof of concept.

    PubMed

    Katz, Itai; Shtirberg, Lazar; Shakour, Gubrail; Blank, Aharon

    2012-06-01

    A new method for obtaining an NMR signal in the Earth's magnetic field (EF) is presented. The method makes use of a simple pulse sequence with only DC fields which is much less demanding than previous approaches in terms of the pulses' rise and fall times. Furthermore, it offers the possibility of obtaining NMR data with enough spectral resolution to allow retrieving high resolution molecular chemical shift (CS) information - a capability that was not considered possible in EF NMR until now. Details of the pulse sequence, the experimental system, and our specially tailored EF NMR probe are provided. The experimental results demonstrate the capability to differentiate between three types of samples made of common fluorine compounds, based on their CS data. Copyright © 2012 Elsevier Inc. All rights reserved.

  14. Carbon Nanotube Bundle Array Cold Cathodes for THz Vacuum Tube Sources

    NASA Astrophysics Data System (ADS)

    Manohara, Harish M.; Toda, Risaku; Lin, Robert H.; Liao, Anna; Bronikowski, Michael J.; Siegel, Peter H.

    2009-12-01

    We present high performance cold cathodes composed of arrays of carbon nanotube bundles that routinely produce > 15 A/cm2 at applied fields of 5 to 8 V/µm without any beam focusing. They have exhibited robust operation in poor vacuums of 10-6 to 10-4 Torr- a typically achievable range inside hermetically sealed microcavities. A new double-SOI process was developed to monolithically integrate a gate and additional beam tailoring electrodes. The ability to design the electrodes for specific requirements makes carbon nanotube field emission sources extremely flexible. The lifetime of these cathodes is found to be affected by two effects: a gradual decay of emission due to anode sputtering, and catastrophic failure because of dislodging of CNT bundles at high fields ( > 10 V/µm).

  15. Wearable optical-digital assistive device for low vision students.

    PubMed

    Afinogenov, Boris I; Coles, James B; Parthasarathy, Sailashri; Press-Williams, Jessica; Tsykunova, Ralina; Vasilenko, Anastasia; Narain, Jaya; Hanumara, Nevan C; Winter, Amos; Satgunam, PremNandhini

    2016-08-01

    People with low vision have limited residual vision that can be greatly enhanced through high levels of magnification. Current assistive technologies are tailored for far field or near field magnification but not both. In collaboration with L.V. Prasad Eye Institute (LVPEI), a wearable, optical-digital assistive device was developed to meet the near and far field magnification needs of students. The critical requirements, system architecture and design decisions for each module were analyzed and quantified. A proof-of-concept prototype was fabricated that can achieve magnification up to 8x and a battery life of up to 8 hours. Potential user evaluation with a Snellen chart showed identification of characters not previously discernible. Further feedback suggested that the system could be used as a general accessibility aid.

  16. Results of a pilot test of a brief computer-assisted tailored HIV prevention intervention for use with a range of demographic and risk groups.

    PubMed

    Zule, William A; Bobashev, Georgiy V; Reif, Susan M; Poulton, Winona; Coomes, Curtis M; Wechsberg, Wendee M

    2013-11-01

    There is a need for brief HIV prevention interventions that can be disseminated and implemented widely. This article reports the results of a small randomized field experiment that compared the relative effects of a brief two-session counselor-delivered computer-tailored intervention and a control condition. The intervention is designed for use with African-American, non-Hispanic white and Hispanic males and females who may be at risk of HIV through unprotected sex, selling sex, male to male sex, injecting drug use or use of stimulants. Participants (n = 120) were recruited using a quota sampling approach and randomized using block randomization, which resulted in ten male and ten female participants of each racial/ethnic group (i.e. African-American, non-Hispanic white and Hispanic) being assigned to either the intervention or a control arm. In logistic regression analyses using a generalized estimating equations approach, at 3-month followup, participants in the intervention arm were more likely than participants in the control arm to report condom use at last sex (Odds ratio [OR] = 4.75; 95 % Confidence interval [CI] = 1.70-13.26; p = 0.003). The findings suggest that a brief tailored intervention may increase condom use. Larger studies with longer followups are needed to determine if these results can be replicated.

  17. Assembly of Reconfigurable Colloidal Structures by Multidirectional Field-Induced Interactions.

    PubMed

    Bharti, Bhuvnesh; Velev, Orlin D

    2015-07-28

    Field-directed colloidal assembly has shown remarkable recent progress in increasing the complexity, degree of control, and multiscale organization of the structures. This has largely been achieved by using particles of complex shapes and polarizabilites (Janus, patchy, shaped, and faceted). We review the fundamentals of the interactions leading to the directed assembly of such structures, the ways to simulate the dynamics of the process, and the effect of particle size, shape, and properties on the type of structure obtained. We discuss how directional polarization interactions induced by external electric and magnetic fields can be used to assemble complex particles or particle mixtures into lattices of tailored structure. Examples of such systems include isotropic and anisotropic shaped particles with surface patches, which form networks and crystals of unusual symmetry by dipolar, quadrupolar, and multipolar interactions in external fields. The emerging trends in making reconfigurable and dynamic structures are discussed.

  18. A multi-functional high voltage experiment apparatus for vacuum surface flashover switch research.

    PubMed

    Zeng, Bo; Su, Jian-cang; Cheng, Jie; Wu, Xiao-long; Li, Rui; Zhao, Liang; Fang, Jin-peng; Wang, Li-min

    2015-04-01

    A multifunctional high voltage apparatus for experimental researches on surface flashover switch and high voltage insulation in vacuum has been developed. The apparatus is composed of five parts: pulse generating unit, axial field unit, radial field unit, and two switch units. Microsecond damped ringing pulse with peak-to-peak voltage 800 kV or unipolar pulse with maximum voltage 830 kV is generated, forming transient axial or radial electrical field. Different pulse waveforms and field distributions make up six experimental configurations in all. Based on this apparatus, preliminary experiments on vacuum surface flashover switch with different flashover dielectric materials have been conducted in the axial field unit, and nanosecond pulse is generated in the radial field unit which makes a pulse transmission line in the experiment. Basic work parameters of this kind of switch such as lifetime, breakdown voltage are obtained.

  19. Tailoring and evaluating an intervention to improve shared decision-making among seniors with dementia, their caregivers, and healthcare providers: study protocol for a randomized controlled trial.

    PubMed

    Giguere, Anik M C; Lawani, Moulikatou Adouni; Fortier-Brochu, Émilie; Carmichael, Pierre-Hugues; Légaré, France; Kröger, Edeltraut; Witteman, Holly O; Voyer, Philippe; Caron, Danielle; Rodríguez, Charo

    2018-06-25

    The increasing prevalence of Alzheimer's disease and other forms of dementia raises new challenges to ensure that healthcare decisions are informed by research evidence and reflect what is important for seniors and their caregivers. Therefore, we aim to evaluate a tailored intervention to help healthcare providers empower seniors and their caregivers in making health-related decisions. In two phases, we will: (1) design and tailor the intervention; and (2) implement and evaluate it. We will use theory and user-centered design to tailor an intervention comprising a distance professional training program on shared decision-making and five shared decision-making tools dealing with difficult decisions often faced by seniors with dementia and their caregivers. Each tool will be designed in two versions, one for clinicians and one for patients. We will recruit 49 clinicians and 27 senior/caregiver to participate in three cycles of design-evaluation-feedback of each intervention components. Besides think-aloud and interview approaches, users will also complete questionnaires based on the Theory of Planned Behavior to identify the factors most likely to influence their adoption of shared decision-making after exposure to the intervention. We will then modify the intervention by adding/enhancing behavior-change techniques targeting these factors. We will evaluate the effectiveness of this tailored intervention before/after implementation, in a two-armed, clustered randomized trial. We will enroll a convenience sample of six primary care clinics (unit of randomization) in the province of Quebec and recruit the clinicians who practice there (mostly family physicians, nurses, and social workers). These clinics will then be randomized to immediate exposure to the intervention or delayed exposure. Overall, we will recruit 180 seniors with dementia, their caregivers, and their healthcare providers. We will evaluate the impact of the intervention on patient involvement in the decision-making process, decisional comfort, patient and caregiver personal empowerment in relation to their own healthcare, patient quality of life, caregiver burden, and decisional regret. The intervention will empower patients and their caregivers in their healthcare, by fostering their participation as partners during the decision-making process and by ensuring they make informed decisions congruent with their values and priorities. ClinicalTrials.org, NCT02956694 . Registered on 31 October 2016.

  20. Public Housing: A Tailored Approach to Energy Retrofits

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dentz, Jordan; Conlin, Francis; Podorson, David

    2014-06-01

    More than 1 million HUD-supported public housing units provide rental housing for eligible low-income families across the country. A survey of over 100 public housing authorities (PHAs) across the country indicated that there is a high level of interest in developing low-cost solutions that improve energy efficiency and can be seamlessly included in the refurbishment process. Further, PHAs, have incentives (both internal and external) to reduce utility bills. ARIES worked with two PHAs to develop packages of energy efficiency retrofit measures the PHAs can cost effectively implement with their own staffs in the normal course of housing operations when unitsmore » are refurbished between occupancies. The energy efficiency turnover protocols emphasized air infiltration reduction, duct sealing and measures that improve equipment efficiency. ARIES documented implementation 10 ten housing units. Total source energy consumption savings was estimated at 6%-10% based on BEopt modeling with a simple payback of 1.7 to 2.2 years. At typical housing unit turnover rates, these measures could impact hundreds of thousands of units per year nationally.« less

  1. Spatial analysis of soil erosion and sediment fluxes: a paired watershed study of two Rappahannock River tributaries, Stafford County, Virginia.

    PubMed

    Ricker, Matthew C; Odhiambo, Ben K; Church, Joseph M

    2008-05-01

    Soil erosion is a serious problem in areas with expanding construction, agricultural production, and improper storm water management. It is important to understand the major processes affecting sediment delivery to surficial water bodies in order to tailor effective mitigation and outreach activities. This study analyzes how naturally occurring and anthropogenic influences, such as urbanization and soil disturbance on steep slopes, are reflected in the amount of soil erosion and sediment delivery within sub-watershed-sized areas. In this study, two sub-watersheds of the Rappahannock River, Horsepen Run and Little Falls Run, were analyzed using the Revised Universal Soil Loss Equation (RUSLE) and a sediment delivery ratio (SDR) to estimate annual sediment flux rates. The RUSLE/SDR analyses for Horsepen Run and Little Falls Run predicted 298 Mg/y and 234 Mg/y, respectively, but nearly identical per-unit-area sediment flux rates of 0.15 Mg/ha/y and 0.18 Mg/ha/y. Suspended sediment sampling indicated greater amounts of sediment in Little Falls Run, which is most likely due to anthropogenic influences. Field analyses also suggest that all-terrain vehicle crossings represent the majority of sediment flux derived from forested areas of Horsepen Run. The combined RUSLE/SDR and field sampling data indicate that small-scale anthropogenic disturbances (ATV trails and construction sites) play a major role in overall sediment flux rates for both basins and that these sites must be properly accounted for when evaluating sediment flux rates at a sub-watershed scale.

  2. Computer-generated tailored feedback letters for smoking cessation: theoretical and empirical variability of tailoring.

    PubMed

    Schumann, Anja; John, Ulrich; Ulbricht, Sabina; Rüge, Jeannette; Bischof, Gallus; Meyer, Christian

    2008-11-01

    This study examines tailored feedback letters of a smoking cessation intervention that is conceptually based on the transtheoretical model, from a content-based perspective. Data of 2 population-based intervention studies, both randomized controlled trials, with total N=1044 were used. The procedure of the intervention, the tailoring principle for the feedback letters, and the content of the intervention materials are described in detail. Theoretical and empirical frequencies of unique feedback letters are presented. The intervention system was able to generate a total of 1040 unique letters with normative feedback only, and almost half a million unique letters with normative and ipsative feedback. Almost every single smoker in contemplation, preparation, action, and maintenance had an empirically unique combination of tailoring variables and received a unique letter. In contrast, many smokers in precontemplation shared a combination of tailoring variables and received identical letters. The transtheoretical model provides an enormous theoretical and empirical variability of tailoring. However, tailoring for a major subgroup of smokers, i.e. those who do not intend to quit, needs improvement. Conceptual ideas for additional tailoring variables are discussed.

  3. "It's Like We Don't Exist": Tailoring Education for Young Women Undergoing Surgery for Early-Stage Breast Cancer

    PubMed

    Recio-Saucedo, Alejandra; Gilbert, Anthony W; Gerty, Sue; Cutress, Ramsey I; Eccles, Diana; Foster, Claire

    2018-03-01

    The implications of a diagnosis and consequent surgical treatment for breast cancer may be different for young women compared to older women. This study investigated the information requirements of young women to support their treatment decision making at diagnosis.
. A purposeful sample of 20 women diagnosed with breast cancer aged 40 years or younger who had undergone surgery and had participated in a large cohort study in the United Kingdom.
. Audio recordings of semistructured interviews were used to reveal information received at the time of surgical treatment.
. Themes identified were types of breast cancer, surgical treatments, nonsurgical treatments, fertility, and surgery and after surgery. Participants felt that information required throughout treatment was influenced by individual life circumstances, such as children or plans for children, relationships, and career intentions. Participants felt information was lacking on the effects of treatment on body image, reconstructive surgery, and genetic predisposition to breast cancer.
. Knowledge of the information requirements of young women diagnosed with breast cancer allows nursing staff to provide tailored support at times identified as most useful.

  4. Tailoring Clinical Services to Address the Unique Needs of Adolescents from the Pregnancy Test to Parenthood

    PubMed Central

    Daley, Alison Moriarty; Sadler, Lois S.; Reynolds, Heather Dawn

    2013-01-01

    Clinicians across disciplines and practice settings are likely to encounter adolescents who are at risk for a pregnancy. In 2010, 34.2/1000 15–19 year old teens had a live birth in the United States, many more will seek care for a pregnancy scare or options counseling. Teen mothers are also at risk for a second or higher order pregnancy during adolescence. This paper provides clinicians with adolescent-friendly clinical and counseling strategies for pregnancy prevention, pre- and post-pregnancy test counseling, pregnancy-related care, and a review of the developmental challenges encountered by teens in the transition to parenthood. Clinicians are in a better position to approach the developmental, health and mental health needs of adolescents related to pregnancy if they understand and appreciate the obstacles adolescents may face negotiating the health care system. In addition, when clinical services are specially tailored to the needs of the adolescent, fewer opportunities will be lost to prevent unintended pregnancies, assist teens into timely prenatal services, and improve outcomes for their pregnancies and the transition to parenthood. PMID:23522339

  5. Tailoring Agility: Promiscuous Pair Story Authoring and Value Calculation

    NASA Astrophysics Data System (ADS)

    Tendon, Steve

    This chapter describes how a multi-national software organization created a business plan involving business units from eight countries that followed an agile way, after two previously failed attempts with traditional approaches. The case is told by the consultant who initiated implementation of agility into requirements gathering, estimation and planning processes in an international setting. The agile approach was inspired by XP, but then tailored to meet the peculiar requirements. Two innovations were critical. The first innovation was promiscuous pair story authoring, where user stories were written by two people (similarly to pair programming), and the pairing changed very often (as frequently as every 15-20 minutes) to achieve promiscuity and cater for diverse point of views. The second innovation was an economic value evaluation (and not the cost) which was attributed to stories. Continuous recalculation of the financial value of the stories allowed to assess the projects financial return. In this case implementation of agility in the international context allowed the involved team members to reach consensus and unanimity of decisions, vision and purpose.

  6. Educator and participant perceptions and cost analysis of stage-tailored educational telephone calls.

    PubMed

    Esters, Onikia N; Boeckner, Linda S; Hubert, Melanie; Horacek, Tanya; Kritsch, Karen R; Oakland, Mary J; Lohse, Barbara; Greene, Geoffrey; Nitzke, Susan

    2008-01-01

    To identify strengths and weaknesses of nutrition education via telephone calls as part of a larger stage-of-change tailored intervention with mailed materials. Evaluative feedback was elicited from educators who placed the calls and respondents who received the calls. An internet and telephone survey of 10 states in the midwestern United States. 21 educators in 10 states reached via the internet and 50 young adults reached via telephone. VARIABLES MEASURED AND ANALYSIS: Rankings of intervention components, ratings of key aspects of educational calls, and cost data (as provided by a lead researcher in each state) were summarized via descriptive statistics. RESULTS, CONCLUSIONS, AND IMPLICATIONS: Educational calls used 6 to 17 minutes of preparation time, required 8 to 15 minutes of contact time, and had a mean estimated cost of $5.82 per call. Low-income young adults favored print materials over educational calls. However, the calls were reported to have positive effects on motivating participants to set goals. Educators who use educational telephone calls to reach young adults, a highly mobile target audience, may require a robust and flexible contact plan.

  7. Uncovering the formation and selection of benzylmalonyl-CoA from the biosynthesis of splenocin and enterocin reveals a versatile way to introduce amino acids into polyketide carbon scaffolds.

    PubMed

    Chang, Chenchen; Huang, Rong; Yan, Yan; Ma, Hongmin; Dai, Zheng; Zhang, Benying; Deng, Zixin; Liu, Wen; Qu, Xudong

    2015-04-01

    Selective modification of carbon scaffolds via biosynthetic engineering is important for polyketide structural diversification. Yet, this scope is currently restricted to simple aliphatic groups due to (1) limited variety of CoA-linked extender units, which lack aromatic structures and chemical reactivity, and (2) narrow acyltransferase (AT) specificity, which is limited to aliphatic CoA-linked extender units. In this report, we uncovered and characterized the first aromatic CoA-linked extender unit benzylmalonyl-CoA from the biosynthetic pathways of splenocin and enterocin in Streptomyces sp. CNQ431. Its synthesis employs a deamination/reductive carboxylation strategy to convert phenylalanine into benzylmalonyl-CoA, providing a link between amino acid and CoA-linked extender unit synthesis. By characterization of its selection, we further validated that AT domains of splenocin, and antimycin polyketide synthases are able to select this extender unit to introduce the phenyl group into their dilactone scaffolds. The biosynthetic machinery involved in the formation of this extender unit is highly versatile and can be potentially tailored for tyrosine, histidine and aspartic acid. The disclosed aromatic extender unit, amino acid-oriented synthetic pathway, and aromatic-selective AT domains provides a systematic breakthrough toward current knowledge of polyketide extender unit formation and selection, and also opens a route for further engineering of polyketide carbon scaffolds using amino acids.

  8. Analysis of alternatives for immobilized low activity waste disposal

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Burbank, D.A.

    This report presents a study of alternative disposal system architectures and implementation strategies to provide onsite near-surface disposal capacity to receive the immobilized low-activity waste produced by the private vendors. The analysis shows that a flexible unit strategy that provides a suite of design solutions tailored to the characteristics of the immobilized low-activity waste will provide a disposal system that best meets the program goals of reducing the environmental, health, and safety impacts; meeting the schedule milestones; and minimizing the life-cycle cost of the program.

  9. Measuring and improving quality of care in an academic medical center.

    PubMed

    Blayney, Douglas W

    2013-05-01

    The Donabedian definition of quality—structure, process, and outcome—provides a useful framework. A relentless focus on measuring process adherence and outcome is critical. Systemic improvements usually require teams to plan and to implement them. The lean or Toyota production system for process improvement is one useful method of organizing work, although different approaches are often necessary at the physician, practice unit, and statewide level. Challenges include scalability of the change (ie, rolling them out across the institution or system), tailoring the information technology tools, and building systems for sustainability.

  10. Shanghai: Front-Runner of Community-Based Eldercare in China.

    PubMed

    Chen, Lin; Han, Wen-Jui

    2016-01-01

    Facing dramatic growth in its elderly population, Shanghai, China's economic center, has strategically exercised decentralized policy-making power to develop community-based service centers for the elderly. A growing number of elders have been using such services, particular dining services, since 2007. We discuss the evolution in community-based eldercare services in Shanghai, using dining services as an example. We also compare these service centers in Shanghai to multipurpose senior centers in the United States to offer policy recommendations for Shanghai and China's growing eldercare industry. Tailored policy recommendations are discussed.

  11. Defining Compensable Injury in Biomedical Research.

    PubMed

    Larkin, Megan E

    2015-01-01

    Biomedical research provides a core social good by enabling medical progress. In the twenty-first century alone, this includes reducing transmission of HIV/AIDS, developing innovative therapies for cancer patients, and exploring the possibilities of personalized medicine. In order to continue to advance medical science, research relies on the voluntary participation of human subjects. Because research is inherently uncertain, unintended harm is an inevitable part of the research enterprise. Currently, injured research participants in the United States must turn to the “litigation lottery” of the tort system in search of compensation. This state of affairs fails research participants, who are too often left uncompensated for devastating losses, and makes the United States an outlier in the international community. In spite of forty years’ worth of Presidential Commissions and other respected voices calling for the development of a no-fault compensation system, no progress has been made to date. One of the reasons for this lack of progress is the failure to develop a coherent ethical basis for an obligation to provide compensation for research related injuries. This problem is exacerbated by the lack of a clear definition of “compensable injury” in the biomedical research context. This article makes a number of important contributions to the scholarship in this growing field. To begin, it examines compensation systems already in existence and concludes that there are four main definitional elements that must be used to define “compensable injury.” Next, it examines the justifications that have been put forth as the basis for an ethical obligation to provide compensation, and settles on retrospective nonmaleficence and distributive and compensatory justice as the most salient and persuasive. Finally, it uses the regulatory elements and the justifications discussed in the first two sections to develop a well-rounded definition of “compensable injury” that is tailored to the biomedical research context. Using this definition, it argues for the development of a first-of- its-kind no-fault compensation system in the United States.

  12. 3D sensor algorithms for spacecraft pose determination

    NASA Astrophysics Data System (ADS)

    Trenkle, John M.; Tchoryk, Peter, Jr.; Ritter, Greg A.; Pavlich, Jane C.; Hickerson, Aaron S.

    2006-05-01

    Researchers at the Michigan Aerospace Corporation have developed accurate and robust 3-D algorithms for pose determination (position and orientation) of satellites as part of an on-going effort supporting autonomous rendezvous, docking and space situational awareness activities. 3-D range data from a LAser Detection And Ranging (LADAR) sensor is the expected input; however, the approach is unique in that the algorithms are designed to be sensor independent. Parameterized inputs allow the algorithms to be readily adapted to any sensor of opportunity. The cornerstone of our approach is the ability to simulate realistic range data that may be tailored to the specifications of any sensor. We were able to modify an open-source raytracing package to produce point cloud information from which high-fidelity simulated range images are generated. The assumptions made in our experimentation are as follows: 1) we have access to a CAD model of the target including information about the surface scattering and reflection characteristics of the components; 2) the satellite of interest may appear at any 3-D attitude; 3) the target is not necessarily rigid, but does have a limited number of configurations; and, 4) the target is not obscured in any way and is the only object in the field of view of the sensor. Our pose estimation approach then involves rendering a large number of exemplars (100k to 5M), extracting 2-D (silhouette- and projection-based) and 3-D (surface-based) features, and then training ensembles of decision trees to predict: a) the 4-D regions on a unit hypersphere into which the unit quaternion that represents the vehicle [Q X, Q Y, Q Z, Q W] is pointing, and, b) the components of that unit quaternion. Results have been quite promising and the tools and simulation environment developed for this application may also be applied to non-cooperative spacecraft operations, Autonomous Hazard Detection and Avoidance (AHDA) for landing craft, terrain mapping, vehicle guidance, path planning and obstacle avoidance.

  13. An array of highly flexible electrodes with a tailored configuration locked by gelatin during implantation-initial evaluation in cortex cerebri of awake rats.

    PubMed

    Agorelius, Johan; Tsanakalis, Fotios; Friberg, Annika; Thorbergsson, Palmi T; Pettersson, Lina M E; Schouenborg, Jens

    2015-01-01

    A major challenge in the field of neural interfaces is to overcome the problem of poor stability of neuronal recordings, which impedes long-term studies of individual neurons in the brain. Conceivably, unstable recordings reflect relative movements between electrode and tissue. To address this challenge, we have developed a new ultra-flexible electrode array and evaluated its performance in awake non-restrained animals. An array of eight separated gold leads (4 × 10 μm), individually flexible in 3D, were cut from a gold sheet using laser milling and insulated with Parylene C. To provide structural support during implantation into rat cortex, the electrode array was embedded in a hard gelatin based material, which dissolves after implantation. Recordings were made during 3 weeks. At termination, the animals were perfused with fixative and frozen to prevent dislocation of the implanted electrodes. A thick slice of brain tissue, with the electrode array still in situ, was made transparent using methyl salicylate to evaluate the conformation of the implanted electrode array. Median noise levels and signal/noise remained relatively stable during the 3 week observation period; 4.3-5.9 μV and 2.8-4.2, respectively. The spike amplitudes were often quite stable within recording sessions and for 15% of recordings where single-units were identified, the highest-SNR unit had an amplitude higher than 150 μV. In addition, high correlations (>0.96) between unit waveforms recorded at different time points were obtained for 58% of the electrode sites. The structure of the electrode array was well preserved 3 weeks after implantation. A new implantable multichannel neural interface, comprising electrodes individually flexible in 3D that retain its architecture and functionality after implantation has been developed. Since the new neural interface design is adaptable, it offers a versatile tool to explore the function of various brain structures.

  14. Tailor-welded blanks and their production

    NASA Astrophysics Data System (ADS)

    Yan, Qi

    2005-01-01

    Tailor welded blanks had been widely used in the automobile industry. A tailor welded blank consists of several flat sheets that were laser welded together before stamping. A combination of different materials, thickness, and coatings could be welded together to form a blank for stamping car body panels. As for the material for automobile industry, this technology was one of the development trend for automobile industry because of its weight reduction, safety improvement and economical use of materials. In this paper, the characters and production of tailor welded blanks in the market were discussed in detail. There had two major methods to produce tailor welded blanks. Laser welding would replace mesh seam welding for the production of tailor welded blanks in the future. The requirements on the edge preparation of unwelded blanks for tailor welded blanks were higher than the other steel processing technology. In order to produce the laser welded blank, there had the other process before the laser welding in the factory. In the world, there had three kinds of patterns for the large volume production of tailor welded blanks. In China, steel factory played the important role in the promotion of the application of tailor welded blanks. The competition for the supply of tailor welded blanks to the automobile industry would become fierce in the near future. As a result, the demand for the quality control on the production of tailor welded blanks would be the first priority concern for the factory.

  15. Characterization and tailoring of porous sol-gel dielectrics for interlayer dielectric applications

    NASA Astrophysics Data System (ADS)

    Rogojevic, Svetlana

    A new, better insulator is needed to replace SiO2 in the next generation of microelectronic devices. The dielectric constant of porous materials can be tailored by adjusting the porosity, so that their use can be extended to more than one generation of devices. Silica xerogel films with wide range of porosities (25 90%) are fabricated by varying the rate of solvent evaporation during spin-coating. Even better porosity control is achieved by using mixtures of high and low boiling point solvents, and allowing one solvent to evaporate completely during spin-coating. The quartz crystal microbalance method was employed to measure the traces of moisture adsorbed in xerogel films of varying porosities. By employing two different surface modifiers, it is demonstrated that the level of hydrophobicity is a function of surface chemistry, and can be tailored by using a suitable surface modifier. To investigate the interaction of xerogels with other materials, metallic layers were deposited on xerogel films, and subsequently annealed. When annealed in the ambient with trace amount of oxygen, Ta and Cu films undergo morphological instabilities. These morphological changes may lead to the erroneous interpretation of the Rutherford backscattering spectra as metal diffusion. When the samples are capped with a Si3N4 layer, Cu and Ta do not show diffusion through xerogel when annealed up to 650°C. Bias-temperature stressing was conducted in order to assess Cu drift through xerogel in the presence of an electric field. Contrary to what is normally observed with other dielectrics, the leakage current and C-V curve shifts were larger with an Al electrode than with a Cu electrode. This indicates that the surface modification of xerogel can contribute to the smaller charge injection from the Cu/xerogel interface, or to the inhibition of Cu diffusion, thus offering a possibility of designing future monolayer diffusion barriers for porous materials. Two possible paths of mass transfer in porous solids are identified: bulk and surface diffusion. Three driving forces are also analyzed: concentration gradient, electric field, and curvature gradient. The model of diffusion through porous solids shows the effects of the electric field, the solid network thickness, porosity, surface and bulk diffusivity. The model is a useful tool for designing and interpreting the experiments, in order to assess the role of surface diffusion in porous materials.

  16. Effect of sample initial magnetic field on the metal magnetic memory NDT result

    NASA Astrophysics Data System (ADS)

    Moonesan, Mahdi; Kashefi, Mehrdad

    2018-08-01

    One of the major concerns regarding the use of Metal Magnetic Memory (MMM) technique is the complexity of residual magnetization effect on output signals. The present study investigates the influence of residual magnetic field on stress induced magnetization. To this end, various initial magnetic fields were induced on a low carbon steel sample, and for each level of residual magnetic field, the sample was subjected to a set of 4-point bending tests and, their corresponding MMM signals were collected from the surface of the bended sample using a tailored metal magnetic memory scanning device. Results showed a strong correlation between sample residual magnetic field and its corresponding level of stress induced magnetic field. It was observed that the sample magnetic field increases with applying the bending stress as long as the initial residual magnet field is low (i.e. <117 mG), but starts decreasing with higher levels of initial residual magnetic fields. Besides, effect of bending stress on the MMM output of a notched sample was investigated. The result, again, showed that MMM signals exhibit a drop at stress concentration zone when sample has high level of initial residual magnetic field.

  17. Unrelated Helpers in a Primitively Eusocial Wasp: Is Helping Tailored Towards Direct Fitness?

    PubMed Central

    Leadbeater, Ellouise; Carruthers, Jonathan M.; Green, Jonathan P.; van Heusden, Jasper; Field, Jeremy

    2010-01-01

    The paper wasp Polistes dominulus is unique among the social insects in that nearly one-third of co-foundresses are completely unrelated to the dominant individual whose offspring they help to rear and yet reproductive skew is high. These unrelated subordinates stand to gain direct fitness through nest inheritance, raising the question of whether their behaviour is adaptively tailored towards maximizing inheritance prospects. Unusually, in this species, a wealth of theory and empirical data allows us to predict how unrelated subordinates should behave. Based on these predictions, here we compare helping in subordinates that are unrelated or related to the dominant wasp across an extensive range of field-based behavioural contexts. We find no differences in foraging effort, defense behaviour, aggression or inheritance rank between unrelated helpers and their related counterparts. Our study provides no evidence, across a number of behavioural scenarios, that the behaviour of unrelated subordinates is adaptively modified to promote direct fitness interests. PMID:20700463

  18. Huge critical current density and tailored superconducting anisotropy in SmFeAsO₀.₈F₀.₁₅ by low-density columnar-defect incorporation.

    PubMed

    Fang, L; Jia, Y; Mishra, V; Chaparro, C; Vlasko-Vlasov, V K; Koshelev, A E; Welp, U; Crabtree, G W; Zhu, S; Zhigadlo, N D; Katrych, S; Karpinski, J; Kwok, W K

    2013-01-01

    Iron-based superconductors could be useful for electricity distribution and superconducting magnet applications because of their relatively high critical current densities and upper critical fields. SmFeAsO₀.₈F₀.₁₅ is of particular interest as it has the highest transition temperature among these materials. Here we show that by introducing a low density of correlated nano-scale defects into this material by heavy-ion irradiation, we can increase its critical current density to up to 2 × 10⁷ A cm⁻² at 5 K--the highest ever reported for an iron-based superconductor--without reducing its critical temperature of 50 K. We also observe a notable reduction in the thermodynamic superconducting anisotropy, from 8 to 4 upon irradiation. We develop a model based on anisotropic electron scattering that predicts that the superconducting anisotropy can be tailored via correlated defects in semimetallic, fully gapped type II superconductors.

  19. Tailoring the Oxygen Content of Graphite and Reduced Graphene Oxide for Specific Applications.

    PubMed

    Morimoto, Naoki; Kubo, Takuya; Nishina, Yuta

    2016-02-25

    Graphene oxide (GO) is widely recognized as a promising material in a variety of fields, but its structure and composition has yet to be fully controlled. We have developed general strategies to control the oxidation degree of graphene-like materials via two methods: oxidation of graphite by KMnO4 in H2SO4 (oGO), and reduction of highly oxidized GO by hydrazine (rGO). Even though the oxygen content may be the same, oGO and rGO have different properties, for example the adsorption ability, oxidation ability, and electron conductivity. These differences in property arise from the difference in the underlying graphitic structure and the type of defect present. Our results can be used as a guideline for the production of tailor-made graphitic carbons. As an example, we show that rGO with 23.1 wt% oxygen showed the best performance as an electrode of an electric double-layer capacitor.

  20. Tailoring the Oxygen Content of Graphite and Reduced Graphene Oxide for Specific Applications

    NASA Astrophysics Data System (ADS)

    Morimoto, Naoki; Kubo, Takuya; Nishina, Yuta

    2016-02-01

    Graphene oxide (GO) is widely recognized as a promising material in a variety of fields, but its structure and composition has yet to be fully controlled. We have developed general strategies to control the oxidation degree of graphene-like materials via two methods: oxidation of graphite by KMnO4 in H2SO4 (oGO), and reduction of highly oxidized GO by hydrazine (rGO). Even though the oxygen content may be the same, oGO and rGO have different properties, for example the adsorption ability, oxidation ability, and electron conductivity. These differences in property arise from the difference in the underlying graphitic structure and the type of defect present. Our results can be used as a guideline for the production of tailor-made graphitic carbons. As an example, we show that rGO with 23.1 wt% oxygen showed the best performance as an electrode of an electric double-layer capacitor.

  1. Capacitively coupled hydrogen plasmas sustained by tailored voltage waveforms: excitation dynamics and ion flux asymmetry

    DOE PAGES

    Bruneau, B.; Diomede, P.; Economou, D. J.; ...

    2016-06-08

    Parallel plate capacitively coupled plasmas in hydrogen at relatively high pressure (~1 Torr) are excited with tailored voltage waveforms containing up to five frequencies. Predictions of a hybrid model combining a particle-in-cell simulation with Monte Carlo collisions and a fluid model are compared to phase resolved optical emission spectroscopy measurements, yielding information on the dynamics of the excitation rate in these discharges. When the discharge is excited with amplitude asymmetric waveforms, the discharge becomes electrically asymmetric, with different ion energies at each of the two electrodes. Unexpectedly, large differences in themore » $$\\text{H}_{2}^{+}$$ fluxes to each of the two electrodes are caused by the different $$\\text{H}_{3}^{+}$$ energies. When the discharge is excited with slope asymmetric waveforms, only weak electrical asymmetry of the discharge is observed. In this case, electron power absorption due to fast sheath expansion at one electrode is balanced by electron power absorption at the opposite electrode due to a strong electric field reversal.« less

  2. Controllable positive exchange bias via redox-driven oxygen migration

    DOE PAGES

    Gilbert, Dustin A.; Olamit, Justin; Dumas, Randy K.; ...

    2016-03-21

    We report that ionic transport in metal/oxide heterostructures offers a highly effective means to tailor material properties via modification of the interfacial characteristics. However, direct observation of ionic motion under buried interfaces and demonstration of its correlation with physical properties has been challenging. Using the strong oxygen affinity of gadolinium, we design a model system of Gd xFe 1-x/NiCoO bilayer films, where the oxygen migration is observed and manifested in a controlled positive exchange bias over a relatively small cooling field range. The exchange bias characteristics are shown to be the result of an interfacial layer of elemental nickel andmore » cobalt, a few nanometres in thickness, whose moments are larger than expected from uncompensated NiCoO moments. This interface layer is attributed to a redox-driven oxygen migration from NiCoO to the gadolinium, during growth or soon after. Ultimately, these results demonstrate an effective path to tailoring the interfacial characteristics and interlayer exchange coupling in metal/oxide heterostructures.« less

  3. Fabrication of microlens array with controllable high NA and tailored optical characteristics using confined ink-jetting

    NASA Astrophysics Data System (ADS)

    Wang, Li; Luo, Yu; Liu, ZengZeng; Feng, Xueming; Lu, Bingheng

    2018-06-01

    This work presents an economic and controllable fabricating method of high numerical aperture (NA) polymer microlens array (MLA) based on ink-jetting technology. The MLAs are ink-jetted to align on micro platforms patterned flexible PDMS substrate. The shape of a sole lens is constructed by the ink-jetted pre-cured polymer volume confined on a micro platform. In this way, MLAs with targeted geometries-as well as tailored optical characteristics-can be printed, leading to freely designed optical properties. High NA from 0.446 to 0.885 and focal lengths between 99.26 μm and 39.45 μm are demonstrated, confirming theoretical predictions. Particularly, both the simulations and experimental measurements in optical properties are carried out, demonstrating that microlenses with shapes beyond a hemisphere (CA > 90°) exhibits higher light utilization efficiency and wider viewing angle. Meanwhile, the MLAs are fabricated on flexible PDMS substrates and can be attached to other curved surfaces for wider field of view imaging and higher sensitivity.

  4. An ecological momentary intervention for smoking cessation: The associations of just-in-time, tailored messages with lapse risk factors.

    PubMed

    Hébert, Emily T; Stevens, Elise M; Frank, Summer G; Kendzor, Darla E; Wetter, David W; Zvolensky, Michael J; Buckner, Julia D; Businelle, Michael S

    2018-03-01

    Smartphone apps can provide real-time, tailored interventions for smoking cessation. The current study examines the effectiveness of a smartphone-based smoking cessation application that assessed risk for imminent smoking lapse multiple times per day and provided messages tailored to current smoking lapse risk and specific lapse triggers. Participants (N=59) recruited from a safety-net hospital smoking cessation clinic completed phone-based ecological momentary assessments (EMAs) 5 times/day for 3 consecutive weeks (1week pre-quit, 2weeks post-quit). Risk for smoking lapse was estimated in real-time using a novel weighted lapse risk estimator. With each EMA, participants received messages tailored to current level of risk for imminent smoking lapse and self-reported presence of smoking urge, stress, cigarette availability, and motivation to quit. Generalized linear mixed model analyses determined whether messages tailored to specific lapse risk factors were associated with greater reductions in these triggers than messages not tailored to specific triggers. Overall, messages tailored to smoking urge, cigarette availability, or stress corresponded with greater reductions in those triggers than messages that were not tailored to specific triggers (p's=0.02 to <0.001). Although messages tailored to stress were associated with greater reductions in stress than messages not tailored to stress, the association was non-significant (p=0.892) when only moments of high stress were included in the analysis. Mobile technology can be used to conduct real-time smoking lapse risk assessment and provide tailored treatment content. Findings provide initial evidence that tailored content may impact users' urge to smoke, stress, and cigarette availability. Copyright © 2017 Elsevier Ltd. All rights reserved.

  5. Promoting a Culture of Tailoring for Systems Engineering Policy Expectations

    NASA Technical Reports Server (NTRS)

    Blankenship, Van A.

    2016-01-01

    NASA's Marshall Space Flight Center (MSFC) has developed an integrated systems engineering approach to promote a culture of tailoring for program and project policy requirements. MSFC's culture encourages and supports tailoring, with an emphasis on risk-based decision making, for enhanced affordability and efficiency. MSFC's policy structure integrates the various Agency requirements into a single, streamlined implementation approach which serves as a "one-stop-shop" for our programs and projects to follow. The engineers gain an enhanced understanding of policy and technical expectations, as well as lesson's learned from MSFC's history of spaceflight and science missions, to enable them to make appropriate, risk-based tailoring recommendations. The tailoring approach utilizes a standard methodology to classify projects into predefined levels using selected mission and programmatic scaling factors related to risk tolerance. Policy requirements are then selectively applied and tailored, with appropriate rationale, and approved by the governing authorities, to support risk-informed decisions to achieve the desired cost and schedule efficiencies. The policy is further augmented by implementation tools and lifecycle planning aids which help promote and support the cultural shift toward more tailoring. The MSFC Customization Tool is an integrated spreadsheet that ties together everything that projects need to understand, navigate, and tailor the policy. It helps them classify their project, understand the intent of the requirements, determine their tailoring approach, and document the necessary governance approvals. It also helps them plan for and conduct technical reviews throughout the lifecycle. Policy tailoring is thus established as a normal part of project execution, with the tools provided to facilitate and enable the tailoring process. MSFC's approach to changing the culture emphasizes risk-based tailoring of policy to achieve increased flexibility, efficiency, and effectiveness in project execution, while maintaining appropriate rigor to ensure mission success.

  6. Ferroelectric Phase Transformations for Energy Conversion and Storage Applications

    NASA Astrophysics Data System (ADS)

    Jo, Hwan Ryul

    Ferroelectric materials possess a spontaneous polarization and actively respond to external mechanical, electrical, and thermal loads. Due to their coupled behavior, ferroelectric materials are used in products such as sensors, actuators, detectors, and transducers. However, most current applications rely on low-energy conversion that involves low magnitude fields. They utilize the low-field linear properties of ferroelectric materials (piezoelectric, pyroelectric) and do not take full advantage of the large-field nonlinear behavior (irreversible domain wall motion, phase transformations) that can occur in ferroelectric materials. When external fields exceed a certain critical level, a structural transformation of the crystal can occur. These phase transformations are accompanied by a much larger response than the linear piezoelectric and pyroelectric responses, by as much as a multiple of ten times in the magnitude. This makes the non-linear behavior in ferroelectric materials promising for energy harvesting and energy storage technologies which will benefit from large-energy conversion. Yet, the ferroelectric phase transformation behavior under large external fields have been less studied and only a few studies have been directed at utilizing this large material response in applications. This dissertation addresses the development ferroelectric phase transformation-based applications, with particular focus on the materials. Development of the ferroelectric phase transformation-based applications was approached in several steps. First, the phase transformation behavior was fully characterized and understood by measuring the phase transformation responses under mechanical, electrical, thermal, and combined loads. Once the behavior was well characterized, systems level applications were addressed. This required assessing the effect of the phase transformation behavior on system performance. The performance of ferroelectric devices is strongly dependent on material properties and phase transformation behavior which can be tailored by modifying the chemical composition, processing conditions, and the loading history (poling). This results in optimization of system performance by tailoring material properties and phase transformation behavior. This approach applied to three ferroelectric phase transformation-based applications: 1. Ferroelectric energy generation 2. Ferroelectric high-energy storage capacitor 3. Ferroelectric thermal energy harvesting. This dissertation has addressed tuning the large field properties for phase transformation-based systems.

  7. Development of patient-centric linguistically tailored psychoeducational messages to support nutrition and medication self-management in type 2 diabetes: a feasibility study

    PubMed Central

    Ellis, Rebecca J Bartlett; Connor, Ulla; Marshall, James

    2014-01-01

    Purpose This study evaluated the feasibility of developing linguistically tailored educational messages designed to match the linguistic styles of patients segmented into types with the Descriptor™, and to determine patient preferences for tailored or standard messages based on their segments. Patients and methods Twenty patients with type 2 diabetes (T2DM) were recruited from a diabetes health clinic. Participants were segmented using the Descriptor™, a language-based questionnaire, to identify patient types based on their control orientation (internal/external), agency (high/low), and affect (positive/negative), which are well studied constructs related to T2DM self-management. Two of the seven self-care behaviors described by the American Association of Diabetes Educators (healthy eating and taking medication) were used to develop standard messages and then linguistically tailored using features of the six different construct segment types of the Descriptor™. A subset of seven participants each provided feedback on their preference for standard or linguistically tailored messages; 12 comparisons between standard and tailored messages were made. Results Overall, the tailored messages were preferred to the standard messages. When the messages were matched to specific construct segment types, the tailored messages were preferred over the standard messages, although this was not statistically significant. Conclusion Linguistically tailoring messages based on construct segments is feasible. Furthermore, tailored messages were more often preferred over standard messages. This study provides some preliminary evidence for tailoring messages based on the linguistic features of control orientation, agency, and affect. The messages developed in this study should be tested in a larger more representative sample. The present study did not explore whether tailored messages were better understood. This research will serve as preliminary evidence to develop future studies with the ultimate goal to design intervention studies to investigate if linguistically tailoring communication within the context of patient education influences patient knowledge, motivation, and activation toward making healthy behavior changes in T2DM self-management. PMID:25336928

  8. Automatically producing tailored web materials for public administration

    NASA Astrophysics Data System (ADS)

    Colineau, Nathalie; Paris, Cécile; Vander Linden, Keith

    2013-06-01

    Public administration organizations commonly produce citizen-focused, informational materials describing public programs and the conditions under which citizens or citizen groups are eligible for these programs. The organizations write these materials for generic audiences because of the excessive human resource costs that would be required to produce personalized materials for everyone. Unfortunately, generic materials tend to be longer and harder to understand than materials tailored for particular citizens. Our work explores the feasibility and effectiveness of automatically producing tailored materials. We have developed an adaptive hypermedia application system that automatically produces tailored informational materials and have evaluated it in a series of studies. The studies demonstrate that: (1) subjects prefer tailored materials over generic materials, even if the tailoring requires answering a set of demographic questions first; (2) tailored materials are more effective at supporting subjects in their task of learning about public programs; and (3) the time required to specify the demographic information on which the tailoring is based does not significantly slow down the subjects in their information seeking task.

  9. eHealth and the use of individually tailored information: A systematic review.

    PubMed

    Conway, Nicholas; Webster, Clare; Smith, Blair; Wake, Deborah

    2017-09-01

    Tailored messages are those that specifically target individuals following an assessment of their unique characteristics. This systematic review assesses the evidence regarding the effectiveness of tailoring within eHealth interventions aimed at chronic disease management. OVID Medline/Embase databases were searched for randomised control trials, controlled clinical, trials, before -after studies, and time series analyses from inception - May 2014. Objectively measured clinical processes/outcomes were considered. Twenty-two papers were eligible for inclusion: 6/22 used fully tailored messaging and 16/22 used partially tailored messages. Two studies isolated tailoring as the active component. The remainder compared intervention with standard care. In all, 12/16 studies measuring clinical processes and 2/6 studies reporting clinical outcomes showed improvements, regardless of target group. Study quality was low and design did not allow for identification of interventions' active component. Heterogeneity precluded meta-analysis. This review has demonstrated that there is a lack of evidence to suggest that tailoring within an eHealth context confers benefit over non-tailored eHealth interventions.

  10. A lithospheric magnetic field model derived from the Swarm satellite magnetic field measurements

    NASA Astrophysics Data System (ADS)

    Hulot, G.; Thebault, E.; Vigneron, P.

    2015-12-01

    The Swarm constellation of satellites was launched in November 2013 and has since then delivered high quality scalar and vector magnetic field measurements. A consortium of several research institutions was selected by the European Space Agency (ESA) to provide a number of scientific products which will be made available to the scientific community. Within this framework, specific tools were tailor-made to better extract the magnetic signal emanating from Earth's the lithospheric. These tools rely on the scalar gradient measured by the lower pair of Swarm satellites and rely on a regional modeling scheme that is more sensitive to small spatial scales and weak signals than the standard spherical harmonic modeling. In this presentation, we report on various activities related to data analysis and processing. We assess the efficiency of this dedicated chain for modeling the lithospheric magnetic field using more than one year of measurements, and finally discuss refinements that are continuously implemented in order to further improve the robustness and the spatial resolution of the lithospheric field model.

  11. Vector network analyzer ferromagnetic resonance spectrometer with field differential detection

    NASA Astrophysics Data System (ADS)

    Tamaru, S.; Tsunegi, S.; Kubota, H.; Yuasa, S.

    2018-05-01

    This work presents a vector network analyzer ferromagnetic resonance (VNA-FMR) spectrometer with field differential detection. This technique differentiates the S-parameter by applying a small binary modulation field in addition to the DC bias field to the sample. By setting the modulation frequency sufficiently high, slow sensitivity fluctuations of the VNA, i.e., low-frequency components of the trace noise, which limit the signal-to-noise ratio of the conventional VNA-FMR spectrometer, can be effectively removed, resulting in a very clean FMR signal. This paper presents the details of the hardware implementation and measurement sequence as well as the data processing and analysis algorithms tailored for the FMR spectrum obtained with this technique. Because the VNA measures a complex S-parameter, it is possible to estimate the Gilbert damping parameter from the slope of the phase variation of the S-parameter with respect to the bias field. We show that this algorithm is more robust against noise than the conventional algorithm based on the linewidth.

  12. Global meteorological data facility for real-time field experiments support and guidance

    NASA Technical Reports Server (NTRS)

    Shipham, Mark C.; Shipley, Scott T.; Trepte, Charles R.

    1988-01-01

    A Global Meteorological Data Facility (GMDF) has been constructed to provide economical real-time meteorological support to atmospheric field experiments. After collection and analysis of meteorological data sets at a central station, tailored meteorological products are transmitted to experiment field sites using conventional ground link or satellite communication techniques. The GMDF supported the Global Tropospheric Experiment Amazon Boundary Layer Experiment (GTE-ABLE II) based in Manaus, Brazil, during July and August 1985; an arctic airborne lidar survey mission for the Polar Stratospheric Clouds (PSC) experiment during January 1986; and the Genesis of Atlantic Lows Experiment (GALE) during January, February and March 1986. GMDF structure is similar to the UNIDATA concept, including meteorological data from the Zephyr Weather Transmission Service, a mode AAA GOES downlink, and dedicated processors for image manipulation, transmission and display. The GMDF improved field experiment operations in general, with the greatest benefits arising from the ability to communicate with field personnel in real time.

  13. Contactless and absolute linear displacement detection based upon 3D printed magnets combined with passive radio-frequency identification

    NASA Astrophysics Data System (ADS)

    Windl, Roman; Abert, Claas; Bruckner, Florian; Huber, Christian; Vogler, Christoph; Weitensfelder, Herbert; Suess, Dieter

    2017-11-01

    Within this work a passive and wireless magnetic sensor, to monitor linear displacements, is proposed. We exploit recent advances in 3D printing and fabricate a polymer bonded magnet with a spatially linear magnetic field component corresponding to the length of the magnet. Regulating the magnetic compound fraction during printing allows specific shaping of the magnetic field distribution. A giant magnetoresistance magnetic field sensor is combined with a radio-frequency identification tag in order to passively monitor the exerted magnetic field of the printed magnet. Due to the tailored magnetic field, a displacement of the magnet with respect to the sensor can be detected within the sub-mm regime. The sensor design provides good flexibility by controlling the 3D printing process according to application needs. Absolute displacement detection using low cost components and providing passive operation, long term stability, and longevity renders the proposed sensor system ideal for structural health monitoring applications.

  14. APPARATUS FOR TRAPPING ENERGETIC CHARGED PARTICLES AND CONFINING THE RESULTING PLASMA

    DOEpatents

    Gibson, G.; Jordan, W.C.; Lauer, E.J.

    1963-04-01

    The present invention relates to a plasma-confining device and a particle injector therefor, the device utilizing a generally toroidal configuration with magnetic fields specifically tailored to the associated injector. The device minimizes the effects of particle end losses and particle drift to the walls with a relatively simple configuration. More particularly, the magnetic field configuration is created by a continuous array of circular, mirror field coils, disposed side-by- side, in particularly spaced relation, to form an endless, toroidal loop. The resulting magnetic field created therein has the appearance of a bumpy'' torus, from which is derived the name Bumpy Torus.'' One of the aforementioned coils is split transverse to its axis, and injection of particles is accomplished along a plane between the halves of such modified coil. The guiding center of the particles follows a constant magnetic field in the plane for a particular distance within the torus, to move therefrom onto a precessional surface which does not intersect the point of injection. (AEC)

  15. On the sound insulation of acoustic metasurface using a sub-structuring approach

    NASA Astrophysics Data System (ADS)

    Yu, Xiang; Lu, Zhenbo; Cheng, Li; Cui, Fangsen

    2017-08-01

    The feasibility of using an acoustic metasurface (AMS) with acoustic stop-band property to realize sound insulation with ventilation function is investigated. An efficient numerical approach is proposed to evaluate its sound insulation performance. The AMS is excited by a reverberant sound source and the standardized sound reduction index (SRI) is numerically investigated. To facilitate the modeling, the coupling between the AMS and the adjacent acoustic fields is formulated using a sub-structuring approach. A modal based formulation is applied to both the source and receiving room, enabling an efficient calculation in the frequency range from 125 Hz to 2000 Hz. The sound pressures and the velocities at the interface are matched by using a transfer function relation based on ;patches;. For illustration purposes, numerical examples are investigated using the proposed approach. The unit cell constituting the AMS is constructed in the shape of a thin acoustic chamber with tailored inner structures, whose stop-band property is numerically analyzed and experimentally demonstrated. The AMS is shown to provide effective sound insulation of over 30 dB in the stop-band frequencies from 600 to 1600 Hz. It is also shown that the proposed approach has the potential to be applied to a broad range of AMS studies and optimization problems.

  16. Web-based tailored nutrition education: results of a randomized controlled trial.

    PubMed

    Oenema, A; Brug, J; Lechner, L

    2001-12-01

    There is ample evidence that printed, computer-tailored nutrition education is a more effective tool for motivating people to change to healthier diets than general nutrition education. New technology is now providing more advanced ways of delivering tailored messages, e.g. via the World Wide Web (WWW). Before disseminating a tailored intervention via the web, it is important to investigate the potential of web-based tailored nutrition education. The present study investigated the immediate impact of web-based computer-tailored nutrition education on personal awareness and intentions related to intake of fat, fruit and vegetables. A randomized controlled trial, with a pre-test-post-test control group design was conducted. Significant differences in awareness and intention to change were found between the intervention and control group at post-test. The tailored intervention was appreciated better, was rated as more personally relevant, and had more subjective impact on opinion and intentions to change than the general nutrition information. Computer literacy had no effect on these ratings. The results indicate that interactive, web-based computer-tailored nutrition education can lead to changes in determinants of behavior. Future research should be aimed at longer-term (behavioral) effects and the practicability of distributing tailored interventions via the WWW.

  17. Magneto Optic Effects and Applications

    DTIC Science & Technology

    1981-11-01

    liquid phase ( LPE ), usually on a single crystal of GdGa garnet (GGG). Their composition is thus easily controlled, and can be tailored according to needs...by the polarizing elements must be taken into account. The result of such a calculation for a garnet film with a * figure of merit of 6.3, is a...vary its magnetization. In order to be able to apply small magnetic fields (80 oe), it has been suggested to use garnet films near their compensation

  18. The matter in extreme conditions instrument at the Linac Coherent Light Source

    DOE PAGES

    Nagler, Bob; Arnold, Brice; Bouchard, Gary; ...

    2015-04-21

    The LCLS beam provides revolutionary capabilities for studying the transient behavior of matter in extreme conditions. The particular strength of the Matter in Extreme Conditions instrument is that it combines the unique LCLS beam with high-power optical laser beams, and a suite of dedicated diagnostics tailored for this field of science. In this paper an overview of the beamline, the capabilities of the instrumentation, and selected highlights of experiments and commissioning results are presented.

  19. The application of the rapid assessment and response methodology for cannabis prevention research among youth in the Netherlands.

    PubMed

    Dupont, Hans B; Kaplan, Charles D; Braam, Richard V; Verbraeck, Hans T; de Vries, Nanne K

    2015-08-01

    Drug prevention methods tailored to specific target groups have become increasingly important. There is a growing need to find ways to rapidly assess and situate target groups in their particular contexts. This need is associated with the implementation of evidence-based interventions (EBIs) for these specific target groups. This article describes the application of Rapid Assessment and Response (RAR) as a necessary first step in designing and implementing a prevention intervention plan for problematic cannabis use among "loitering" youth in the South of the Netherlands. Seven RAR studies were conducted using an innovative stepwise model in which the prevention field worker is central. The normative structure for the use of cannabis was found to vary across the neighborhoods of the RAR studies and emerged as the focal point in designing a suitable response. The RAR studies also identified the need in the prevention toolbox for a tailored, low-threshold, effective, individual brief intervention for youth problematic cannabis use. The RAR was found to provide a powerful methodology for detecting target groups and generating contextual and normative data that enable the prevention field worker to select and adapt from the spectrum of existing Evidence based Interventions (EBIs) or develop the most promising model for implementation with the specific target group. Copyright © 2014 The Authors. Published by Elsevier B.V. All rights reserved.

  20. Rational engineering of physicochemical properties of nanomaterials for biomedical applications with nanotoxicological perspectives.

    PubMed

    Navya, P N; Daima, Hemant Kumar

    2016-01-01

    Innovative engineered nanomaterials are at the leading edge of rapidly emerging fields of nanobiotechnology and nanomedicine. Meticulous synthesis, unique physicochemical properties, manifestation of chemical or biological moieties on the surface of materials make engineered nanostructures suitable for a variety of biomedical applications. Besides, tailored nanomaterials exhibit entirely novel therapeutic applications with better functionality, sensitivity, efficiency and specificity due to their customized unique physicochemical and surface properties. Additionally, such designer made nanomaterials has potential to generate series of interactions with various biological entities including DNA, proteins, membranes, cells and organelles at nano-bio interface. These nano-bio interactions are driven by colloidal forces and predominantly depend on the dynamic physicochemical and surface properties of nanomaterials. Nevertheless, recent development and atomic scale tailoring of various physical, chemical and surface properties of nanomaterials is promising to dictate their interaction in anticipated manner with biological entities for biomedical applications. As a result, rationally designed nanomaterials are in extensive demand for bio-molecular detection and diagnostics, therapeutics, drug and gene delivery, fluorescent labelling, tissue engineering, biochemical sensing and other pharmaceuticals applications. However, toxicity and risk associated with engineered nanomaterials is rather unclear or not well understood; which is gaining considerable attention and the field of nanotoxicology is evolving promptly. Therefore, this review explores current knowledge of articulate engineering of nanomaterials for biomedical applications with special attention on potential toxicological perspectives.

  1. Ultrathin 2D Photocatalysts: Electronic-Structure Tailoring, Hybridization, and Applications.

    PubMed

    Di, Jun; Xiong, Jun; Li, Huaming; Liu, Zheng

    2018-01-01

    As a sustainable technology, semiconductor photocatalysis has attracted considerable interest in the past several decades owing to the potential to relieve or resolve energy and environmental-pollution issues. By virtue of their unique structural and electronic properties, emerging ultrathin 2D materials with appropriate band structure show enormous potential to achieve efficient photocatalytic performance. Here, the state-of-the-art progress on ultrathin 2D photocatalysts is reviewed and a critical appraisal of the classification, controllable synthesis, and formation mechanism of ultrathin 2D photocatalysts is presented. Then, different strategies to tailor the electronic structure of ultrathin 2D photocatalysts are summarized, including component tuning, thickness tuning, doping, and defect engineering. Hybridization with the introduction of a foreign component and maintaining the ultrathin 2D structure is presented to further boost the photocatalytic performance, such as quantum dots/2D materials, single atoms/2D materials, molecular/2D materials, and 2D-2D stacking materials. More importantly, the advancement of versatile photocatalytic applications of ultrathin 2D photocatalysts in the fields of water oxidation, hydrogen evolution, CO 2 reduction, nitrogen fixation, organic syntheses, and removal pollutants is discussed. Finally, the future opportunities and challenges regarding ultrathin 2D photocatalysts to bring about new opportunities for future research in the field of photocatalysis are also presented. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  2. Rational engineering of physicochemical properties of nanomaterials for biomedical applications with nanotoxicological perspectives

    NASA Astrophysics Data System (ADS)

    Navya, P. N.; Daima, Hemant Kumar

    2016-02-01

    Innovative engineered nanomaterials are at the leading edge of rapidly emerging fields of nanobiotechnology and nanomedicine. Meticulous synthesis, unique physicochemical properties, manifestation of chemical or biological moieties on the surface of materials make engineered nanostructures suitable for a variety of biomedical applications. Besides, tailored nanomaterials exhibit entirely novel therapeutic applications with better functionality, sensitivity, efficiency and specificity due to their customized unique physicochemical and surface properties. Additionally, such designer made nanomaterials has potential to generate series of interactions with various biological entities including DNA, proteins, membranes, cells and organelles at nano-bio interface. These nano-bio interactions are driven by colloidal forces and predominantly depend on the dynamic physicochemical and surface properties of nanomaterials. Nevertheless, recent development and atomic scale tailoring of various physical, chemical and surface properties of nanomaterials is promising to dictate their interaction in anticipated manner with biological entities for biomedical applications. As a result, rationally designed nanomaterials are in extensive demand for bio-molecular detection and diagnostics, therapeutics, drug and gene delivery, fluorescent labelling, tissue engineering, biochemical sensing and other pharmaceuticals applications. However, toxicity and risk associated with engineered nanomaterials is rather unclear or not well understood; which is gaining considerable attention and the field of nanotoxicology is evolving promptly. Therefore, this review explores current knowledge of articulate engineering of nanomaterials for biomedical applications with special attention on potential toxicological perspectives.

  3. Augmented reality-assisted bypass surgery: embracing minimal invasiveness.

    PubMed

    Cabrilo, Ivan; Schaller, Karl; Bijlenga, Philippe

    2015-04-01

    The overlay of virtual images on the surgical field, defined as augmented reality, has been used for image guidance during various neurosurgical procedures. Although this technology could conceivably address certain inherent problems of extracranial-to-intracranial bypass procedures, this potential has not been explored to date. We evaluate the usefulness of an augmented reality-based setup, which could help in harvesting donor vessels through their precise localization in real-time, in performing tailored craniotomies, and in identifying preoperatively selected recipient vessels for the purpose of anastomosis. Our method was applied to 3 patients with Moya-Moya disease who underwent superficial temporal artery-to-middle cerebral artery anastomoses and 1 patient who underwent an occipital artery-to-posteroinferior cerebellar artery bypass because of a dissecting aneurysm of the vertebral artery. Patients' heads, skulls, and extracranial and intracranial vessels were segmented preoperatively from 3-dimensional image data sets (3-dimensional digital subtraction angiography, angio-magnetic resonance imaging, angio-computed tomography), and injected intraoperatively into the operating microscope's eyepiece for image guidance. In each case, the described setup helped in precisely localizing donor and recipient vessels and in tailoring craniotomies to the injected images. The presented system based on augmented reality can optimize the workflow of extracranial-to-intracranial bypass procedures by providing essential anatomical information, entirely integrated to the surgical field, and help to perform minimally invasive procedures. Copyright © 2015 Elsevier Inc. All rights reserved.

  4. Final Technical Report: "New Tools for Physics with Low-energy Antimatter"

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Surko, Clifford M.

    2013-10-02

    The objective of this research is to develop new tools to manipulate antimatter plasmas and to tailor them for specific scientific and technical uses. The work has two specific objectives. One is establishing the limits for positron accumulation and confinement in the form of single-component plasmas in Penning-Malmberg traps. This technique underpins a wealth of antimatter applications. A second objective is to develop an understanding of the limits for formation of cold, bright positron beams. The research done in this grant focused on particular facets of these goals. One focus was extracting tailored beams from a high-field Penning-Malmberg trap frommore » the magnetic field to form new kinds of high-quality electrostatic beams. A second goal was to develop the technology for colder trap-based beams using a cryogenically cooled buffer gas. A third objective was to conduct the basic plasma research to develop a new high-capacity multicell trap (MCT) for research with antimatter. Progress is reported here in all three areas. While the goal of this research is to develop new tools for manipulating positrons (i.e., the antiparticles of electrons), much of the work was done with test electron plasmas for increased data rate. Some of the techniques developed in the course of this work are also relevant to the manipulation and use of antiprotons.« less

  5. Nonlinear unitary transformations of space-variant polarized light fields from self-induced geometric-phase optical elements

    NASA Astrophysics Data System (ADS)

    Kravets, Nina; Brasselet, Etienne

    2018-01-01

    We propose to couple the optical orientational nonlinearities of liquid crystals with their ability to self-organize to tailor them to control space-variant-polarized optical fields in a nonlinear manner. Experimental demonstration is made using a liquid crystal light valve that behaves like a light-driven geometric phase optical element. We also unveil two original nonlinear optical processes, namely self-induced separability and nonseparability. These results contribute to the advancement of nonlinear singular optics that is still in its infancy despite 25 years of effort, which may foster the development of nonlinear protocols to manipulate high-dimensional optical information both in the classical and quantum regimes.

  6. Review of controlled fusion research using laser heating.

    NASA Technical Reports Server (NTRS)

    Hertzberg, A.

    1973-01-01

    Development of methods for generating high laser pulse energy has stimulated research leading to new ideas for practical controlled thermonuclear fusion machines. A review is presented of some important efforts in progress, and two different approaches have been selected as examples for discussion. One involves the concept of very short pulse lasers with power output tailored, in time, to obtain a nearly isentropic compression of a deuterium-tritium pellet to very high densities and temperatures. A second approach utilizing long wavelength, long pulse, efficient gas lasers to heat a column of plasma contained in a solenoidal field is also discussed. The working requirements of the laser and various magnetic field geometries of this approach are described.

  7. RNA interference: ready to silence cancer?

    PubMed

    Mocellin, Simone; Costa, Rodolfo; Nitti, Donato

    2006-01-01

    RNA interference (RNAi) is considered the most promising functional genomics tool recently developed. As in other medical fields, this biotechnology might revolutionize the approach to dissecting the biology of cancer, ultimately speeding up the discovery pace of novel targets suitable for molecularly tailored antitumor therapies. In addition, preclinical results suggest that RNAi itself might be used as a therapeutic weapon. With the aim of illustrating not only the potentials but also the current limitations of RNAi as a tool in the fight against cancer, here we summarize the physiology of RNAi, discuss the main technical issues of RNAi-based gene silencing, and review some of the most interesting preclinical results obtained so far with its implementation in the field of oncology.

  8. Prescriptive unitarity

    DOE PAGES

    Bourjaily, Jacob L.; Herrmann, Enrico; Trnka, Jaroslav

    2017-06-12

    We introduce a prescriptive approach to generalized unitarity, resulting in a strictly-diagonal basis of loop integrands with coefficients given by specifically-tailored residues in field theory. We illustrate the power of this strategy in the case of planar, maximally supersymmetric Yang-Mills theory (SYM), where we construct closed-form representations of all (n-point N k MHV) scattering amplitudes through three loops. The prescriptive approach contrasts with the ordinary description of unitarity-based methods by avoiding any need for linear algebra to determine integrand coefficients. We describe this approach in general terms as it should have applications to many quantum field theories, including those withoutmore » planarity, supersymmetry, or massless spectra defined in any number of dimensions.« less

  9. FAIMS Mobile: Flexible, open-source software for field research

    NASA Astrophysics Data System (ADS)

    Ballsun-Stanton, Brian; Ross, Shawn A.; Sobotkova, Adela; Crook, Penny

    2018-01-01

    FAIMS Mobile is a native Android application supported by an Ubuntu server facilitating human-mediated field research across disciplines. It consists of 'core' Java and Ruby software providing a platform for data capture, which can be deeply customised using 'definition packets' consisting of XML documents (data schema and UI) and Beanshell scripts (automation). Definition packets can also be generated using an XML-based domain-specific language, making customisation easier. FAIMS Mobile includes features allowing rich and efficient data capture tailored to the needs of fieldwork. It also promotes synthetic research and improves transparency and reproducibility through the production of comprehensive datasets that can be mapped to vocabularies or ontologies as they are created.

  10. Coherent electronic wave packet motion in C(60) controlled by the waveform and polarization of few-cycle laser fields.

    PubMed

    Li, H; Mignolet, B; Wachter, G; Skruszewicz, S; Zherebtsov, S; Süssmann, F; Kessel, A; Trushin, S A; Kling, Nora G; Kübel, M; Ahn, B; Kim, D; Ben-Itzhak, I; Cocke, C L; Fennel, T; Tiggesbäumker, J; Meiwes-Broer, K-H; Lemell, C; Burgdörfer, J; Levine, R D; Remacle, F; Kling, M F

    2015-03-27

    Strong laser fields can be used to trigger an ultrafast molecular response that involves electronic excitation and ionization dynamics. Here, we report on the experimental control of the spatial localization of the electronic excitation in the C_{60} fullerene exerted by an intense few-cycle (4 fs) pulse at 720 nm. The control is achieved by tailoring the carrier-envelope phase and the polarization of the laser pulse. We find that the maxima and minima of the photoemission-asymmetry parameter along the laser-polarization axis are synchronized with the localization of the coherent electronic wave packet at around the time of ionization.

  11. Cost effectiveness of computer tailored and non-tailored smoking cessation letters in general practice: randomised controlled trial

    PubMed Central

    Lennox, A Scott; Osman, Liesl M; Reiter, Ehud; Robertson, Roma; Friend, James; McCann, Ian; Skatun, Diane; Donnan, Peter T

    2001-01-01

    Objectives To develop and evaluate, in a primary care setting, a computerised system for generating tailored letters about smoking cessation. Design Randomised controlled trial. Setting Six general practices in Aberdeen, Scotland. Participants 2553 smokers aged 17 to 65. Interventions All participants received a questionnaire asking about their smoking. Participants subsequently received either a computer tailored or a non-tailored, standard letter on smoking cessation, or no letter. Main outcome measures Prevalence of validated abstinence at six months; change in intention to stop smoking in the next six months. Results The validated cessation rate at six months was 3.5% (30/857) (95% confidence interval 2.3% to 4.7%) for the tailored letter group, 4.4% (37/846) (3.0% to 5.8%) for the non-tailored letter group, and 2.6% (22/850) (1.5% to 3.7%) for the control (no letter) group. After adjustment for significant covariates, the cessation rate was 66% greater (−4% to 186%; P=0.07) in the non-tailored letter group than that in the no letter group. Among participants who smoked <20 cigarettes per day, the cessation rate in the non-tailored letter group was 87% greater (0% to 246%; P=0.05) than that in the no letter group. Among heavy smokers who did not quit, a 76% higher rate of positive shift in “stage of change” (intention to quit within a particular period of time) was seen compared with those who received no letter (11% to 180%; P=0.02). The increase in cost for each additional quitter in the non-tailored letter group compared with the no letter group was £89. Conclusions In a large general practice, a brief non-tailored letter effectively increased cessation rates among smokers. A tailored letter was not effective in increasing cessation rates but promoted shift in movement towards cessation (“stage of change”) in heavy smokers. As a pragmatic tool to encourage cessation of smoking, a mass mailing of non-tailored letters from general practices is more cost effective than computer tailored letters or no letters. What is already known on this topicBrief opportunistic advice on stopping smoking that is given face to face by health professionals increases rates of cessation by 2-3%Intensive, expert-led interventions increase cessation rates by up to 20% or more but are expensive and reach only a small proportion of smokersWritten advice tailored to an individual's “stage of change” (intention to stop in a particular period of time) has been claimed to be as effective as intensive interventions, but previous studies of tailored written advice did not biochemically validate cessationWhat this paper addsA simple standard letter sent to patients of general practices that gave brief advice on stopping smoking increased the biochemically validated rate of cessation by 2%A letter tailored to the individual's “stage of change” was not more effective than the non-tailored standard letterAlthough the increase in cessation resulting from the non-tailored standard letter was small, this intervention was highly cost effective PMID:11397745

  12. Lay Health Influencers: How They Tailor Brief Tobacco Cessation Interventions

    ERIC Educational Resources Information Center

    Yuan, Nicole P.; Castaneda, Heide; Nichter, Mark; Nichter, Mimi; Wind, Steven; Carruth, Lauren; Muramoto, Myra

    2012-01-01

    Interventions tailored to individual smoker characteristics have increasingly received attention in the tobacco control literature. The majority of tailored interventions are generated by computers and administered with printed materials or web-based programs. The purpose of this study was to examine the tailoring activities of community lay…

  13. Architectonics: Design of Molecular Architecture for Functional Applications.

    PubMed

    Avinash, M B; Govindaraju, Thimmaiah

    2018-02-20

    The term architectonics has its roots in the architectural and philosophical (as early as 1600s) literature that refers to "the theory of structure" and "the structure of theory", respectively. The concept of architectonics has been adapted to advance the field of molecular self-assembly and termed as molecular architectonics. In essence, the methodology of organizing molecular units in the required and controlled configurations to develop advanced functional systems for materials and biological applications comprises the field of molecular architectonics. This concept of designing noncovalent systems enables to focus on different functional aspects of designer molecules for biological and nonbiological applications and also strengthens our efforts toward the mastery over the art of controlled molecular self-assemblies. Programming complex molecular interactions and assemblies for specific functions has been one of the most challenging tasks in the modern era. Meticulously ordered molecular assemblies can impart remarkable developments in several areas spanning energy, health, and environment. For example, the well-defined nano-, micro-, and macroarchitectures of functional molecules with specific molecular ordering possess potential applications in flexible electronics, photovoltaics, photonic crystals, microreactors, sensors, drug delivery, biomedicine, and superhydrophobic coatings, among others. The functional molecular architectures having unparalleled properties are widely evident in various designs of Nature. By drawing inspirations from Nature, intended molecular architectures can be designed and developed to harvest various functions, as there is an inexhaustible resource and scope. In this Account, we present exquisite designer molecules developed by our group and others with an objective to master the art of molecular recognition and self-assembly for functional applications. We demonstrate the tailor-ability of molecular self-assemblies by employing biomolecules like amino acids and nucleobases as auxiliaries. Naphthalenediimide (NDI), perylenediimide (PDI), and few other molecular systems serve as functional modules. The effects of stereochemistry and minute structural modifications in the molecular designs on the supramolecular interactions, and construction of self-assembled zero-dimensional (OD), one-dimensional (1D), and two-dimensional (2D) nano- and microarchitectures like particles, spheres, cups, bowls, fibers, belts, helical belts, supercoiled helices, sheets, fractals, and honeycomb-like arrays are discussed in extensive detail. Additionally, we present molecular systems that showcase the elegant designs of coassembly, templated assembly, hierarchical assembly, transient self-assembly, chiral denaturation, retentive helical memory, self-replication, supramolecular regulation, supramolecular speciation, supernon linearity, dynamic pathway complexity, supramolecular heterojunction, living supramolecular polymerization, and molecular machines. Finally, we describe the molecular engineering principles learnt over the years that have led to several applications, namely, organic electronics, self-cleaning, high-mechanical strength, and tissue engineering.

  14. Developing strong response capacity: training volunteers in the medical reserve corps.

    PubMed

    Ye, Jiali; Stanford, Stacy; Gousse, Tahlia; Tosatto, Robert J

    2014-12-01

    The success of the Medical Reserve Corps (MRC) is dependent on the ability of volunteers to respond in a timely and effective manner. This study aimed to assess the current status of MRC volunteer training and to examine the association between MRC characteristics and provision of training. The data for this study were drawn from the 2013 Network Profile Survey of the MRC, which was administered to active MRC unit leaders or designated alternates of 962 units across the country in April to May of 2013. Over 80% of MRCs had a training plan. Ninety-one percent of MRCs offered one or more training courses to volunteers, and 73% indicated requirements for mandatory training. Approximately 84% of MRC units collaborated with other organizations to conduct trainings. Units with more volunteers (>150) were 3 times as likely to have a plan for volunteer training as were those with fewer volunteers (≤50). Compared to units with a full-time leader, those with leaders who were volunteers were only 0.57 times as likely to have a training plan. An overwhelming majority of MRC units provide critical training to their volunteers prior to an emergency deployment. To further strengthen the overall MRC capacities, it is important for MRC units to have a training plan tailored to their community needs and features, make full use of available training resources, and collaborate with partner organizations.

  15. Reversible magnetic-field-induced martensitic transformation over a wide temperature window in Ni42-xCoxCu8Mn37Ga13 alloys

    NASA Astrophysics Data System (ADS)

    Hua, Hui; Wang, Jingmin; Jiang, Chengbao; Xu, Huibin

    2018-05-01

    Ni42-xCoxCu8Mn37Ga13 (0 ≤ x ≤ 14) alloys are reported to exhibit a magnetostructural transition from weakly-magnetic martensite to ferromagnetic austenite over a rather wide temperature window ranging from 200 K to 380 K. Simultaneously a large magnetization change Δσ of up to 105 Am2 kg-1 is obtained at the martensitic transformation. A reversible magnetic-field-induced martensitic transformation is realized, resulting in a large magnetocaloric effect related to the high magnetic entropy change with a broad working temperature span. This work shows how it is possible to effectively tailor the magnetostructural transition in Ni-Mn-Ga alloys so as to achieve a reversible magnetic-field-induced martensitic transformation and associated functionalities.

  16. A streak camera based fiber optic pulsed polarimetry technique for magnetic sensing to sub-mm resolution.

    PubMed

    Smith, R J; Weber, T E

    2016-11-01

    The technique of fiber optic pulsed polarimetry, which provides a distributed (local) measurement of the magnetic field along an optical fiber, has been improved to the point where, for the first time, photocathode based optical detection of backscatter is possible with sub-mm spatial resolutions. This has been realized through the writing of an array of deterministic fiber Bragg gratings along the fiber, a so-called backscatter-tailored optical fiber, producing a 34 000-fold increase in backscatter levels over Rayleigh. With such high backscatter levels, high repetition rate lasers are now sufficiently bright to allow near continuous field sensing in both space and time with field resolutions as low as 0.005 T and as high as 170 T over a ∼mm interval given available fiber materials.

  17. Adiabatically modeling quantum gates with two-site Heisenberg spins chain: Noise vs interferometry

    NASA Astrophysics Data System (ADS)

    Jipdi, M. N.; Tchoffo, M.; Fai, L. C.

    2018-02-01

    We study the Landau Zener (LZ) dynamics of a two-site Heisenberg spin chain assisted with noise and focus on the implementation of logic gates via the resulting quantum interference. We present the evidence of the quantum interference phenomenon in triplet spin states and confirm that, three-level systems mimic Landau-Zener-Stückelberg (LZS) interferometers with occupancies dependent on the effective phase. It emerges that, the critical parameters tailoring the system are obtained for constructive interferences where the two sets of the chain are found to be maximally entangled. Our findings demonstrate that the enhancement of the magnetic field strength suppresses noise effects; consequently, the noise severely impacts the occurrence of quantum interference for weak magnetic fields while for strong fields, quantum interference subsists and allows the modeling of universal sets of quantum gates.

  18. Ultrahigh-definition dynamic 3D holographic display by active control of volume speckle fields

    NASA Astrophysics Data System (ADS)

    Yu, Hyeonseung; Lee, Kyeoreh; Park, Jongchan; Park, Yongkeun

    2017-01-01

    Holographic displays generate realistic 3D images that can be viewed without the need for any visual aids. They operate by generating carefully tailored light fields that replicate how humans see an actual environment. However, the realization of high-performance, dynamic 3D holographic displays has been hindered by the capabilities of present wavefront modulator technology. In particular, spatial light modulators have a small diffraction angle range and limited pixel number limiting the viewing angle and image size of a holographic 3D display. Here, we present an alternative method to generate dynamic 3D images by controlling volume speckle fields significantly enhancing image definition. We use this approach to demonstrate a dynamic display of micrometre-sized optical foci in a volume of 8 mm × 8 mm × 20 mm.

  19. Magnetic hyperthermia performance of magnetite nanoparticle assemblies under different driving fields

    NASA Astrophysics Data System (ADS)

    Wu, Kai; Wang, Jian-Ping

    2017-05-01

    The heating performance of magnetic nanoparticles (MNPs) under an alternating magnetic field (AMF) is dependent on several factors. Optimizing these factors improves the heating efficiency for cancer therapy and meanwhile lowers the MNP treatment dosage. AMF is one of the most easily controllable variables to enhance the efficiency of heat generation. This paper investigated the optimal magnetic field strength and frequency for an assembly of magnetite nanoparticles. For hyperthermia treatment in clinical applications, monodispersed NPs are forming nanoclusters in target regions where a strong magnetically interactive environment is anticipated, which leads to a completely different situation than MNPs in ferrofluids. Herein, the energy barrier model is revisited and Néel relaxation time is tailored for high MNP packing densities. AMF strength and frequency are customized for different magnetite NPs to achieve the highest power generation and the best hyperthermia performance.

  20. A pilot study: the development of a culturally tailored Malaysian Diabetes Education Module (MY-DEMO) based on the Health Belief Model.

    PubMed

    Ahmad, Badariah; Ramadas, Amutha; Kia Fatt, Quek; Md Zain, Anuar Zaini

    2014-04-08

    Diabetes education and self-care remains the cornerstone of diabetes management. There are many structured diabetes modules available in the United Kingdom, Europe and United States of America. Contrastingly, few structured and validated diabetes modules are available in Malaysia. This pilot study aims to develop and validate diabetes education material suitable and tailored for a multicultural society like Malaysia. The theoretical framework of this module was founded from the Health Belief Model (HBM). The participants were assessed using 6-item pre- and post-test questionnaires that measured some of the known HBM constructs namely cues to action, perceived severity and perceived benefit. Data was analysed using PASW Statistics 18.0. The pre- and post-test questionnaires were administered to 88 participants (31 males). In general, there was a significant increase in the total score in post-test (97.34 ± 6.13%) compared to pre-test (92.80 ± 12.83%) (p < 0.05) and a significant increase in excellent score (>85%) at post-test (84.1%) compared to pre-test (70.5%) (p < 0.05). There was an improvement in post-test score in 4 of 6 items tested. The remaining 2 items which measured the perceived severity and cues to action had poorer post-test score. The preliminary results from this pilot study suggest contextualised content material embedded within MY DEMO maybe suitable for integration with the existing diabetes education programmes. This was the first known validated diabetes education programme available in the Malay language.

  1. Efficient and Tunable Three-Dimensional Functionalization of Fully Zwitterionic Antifouling Surface Coatings.

    PubMed

    Lange, Stefanie C; van Andel, Esther; Smulders, Maarten M J; Zuilhof, Han

    2016-10-11

    To enhance the sensitivity and selectivity of surface-based (bio)sensors, it is of crucial importance to diminish background signals that arise from the nonspecific binding of biomolecules, so-called biofouling. Zwitterionic polymer brushes have been shown to be excellent antifouling materials. However, for sensing purposes, antifouling does not suffice but needs to be combined with the possibility to efficiently modify the brush with recognition units. So far this has been achieved only at the expense of either antifouling properties or binding capacity. Herein we present a conceptually new approach by integrating both characteristics into a single tailor-made monomer: a novel sulfobetaine-based zwitterionic monomer equipped with a clickable azide moiety. Copolymerization of this monomer with a well-established standard sulfobetaine monomer results in highly antifouling surface coatings with a large yet tunable number of clickable groups present throughout the entire brush. Subsequent functionalization of the azido brushes via widely used strain-promoted alkyne azide click reactions yields fully zwitterionic 3D-functionalized coatings with a recognition unit of choice that can be tailored for any specific application. Here we show a proof of principle with biotin-functionalized brushes on Si 3 N 4 that combine excellent antifouling properties with specific avidin binding from a protein mixture. The signal-to-noise ratio is significantly improved over that of traditional chain-end modification of sulfobetaine polymer brushes, even if the azide content is lowered to 1%. This therefore offers a viable approach to the development of biosensors with greatly enhanced performance on any surface.

  2. Facilitators and barriers to initiating change in medical intensive care unit survivors with alcohol use disorders: a qualitative study.

    PubMed

    Clark, Brendan J; Jones, Jacqueline; Cook, Paul; Tian, Karen; Moss, Marc

    2013-10-01

    Alcohol abuse and dependence are collectively referred to as alcohol use disorders (AUD). An AUD is present in up to one third of patients admitted to an intensive care unit (ICU). We sought to understand the barriers and facilitators to change in ICU survivors with an AUD to provide a foundation upon which to tailor alcohol-related interventions. We used a qualitative approach with a broad constructivist framework, conducting semistructured interviews in medical ICU survivors with an AUD. Patients were included if they were admitted to 1 of 2 medical ICUs and were excluded if they refused participation, were unable to participate, or did not speak English. Digitally recorded and professionally transcribed interviews were analyzed using a general inductive approach and grouped into themes. Nineteen patients were included, with an average age of 51 (interquartile range, 36-51) years and an average Acute Physiology and Chronic Health Evaluation II score of 9 (interquartile range, 5-13); 68% were white, 74% were male, and the most common reason for admission was alcohol withdrawal (n=8). We identified 5 facilitators of change: empathy of the inpatient health care environment, recognition of accumulating problems, religion, pressure from others to stop drinking, and trigger events. We identified 3 barriers to change: missed opportunities, psychiatric comorbidity, and cognitive dysfunction. Social networks were identified as either a barrier or facilitator to change depending on the specific context. Alcohol-related interventions to motivate and sustain behavior change could be tailored to ICU survivors by accounting for unique barriers and facilitators. © 2013.

  3. Severe and fatal obstetric injury claims in relation to labor unit volume.

    PubMed

    Milland, Maria; Mikkelsen, Kim L; Christoffersen, Jens K; Hedegaard, Morten

    2015-05-01

    To assess possible association between the incidence of approved claims for severe and fatal obstetric injuries and delivery volume in Denmark. A nationwide panel study of labor units. Claimants seeking financial compensation due to injuries occurring in labor units in 1995-2012. Exposure information regarding the annual number of deliveries per labor unit was retrieved from the Danish National Birth Register. Outcome information was retrieved from the Danish Patient Compensation Association. Exposure was categorized in delivery volume quintiles as annual volume per labor unit: (10-1377), (1378-2016), (2017-2801), (2802-3861), (3862-6659). Five primary measures of outcome were used. Incidence rate ratios of (A) Submitted claims, (B) Approved claims, (C) Approved severe injury claims (120% degree of disability), (D) Approved fatal injury claims, and (C+D) Combined. 1 151 734 deliveries in 51 labor units and 1872 submitted claims were included. The incidence rate ratios of approved claims overall, of approved fatal injury claims, and of approved severe and fatal injuries combined increased significantly with decreasing annual delivery volume. Face value incidence rate ratios of approved severe injuries increased with decreasing labor unit volume, but the association did not reach statistical significance. High volume labor units appear associated with fewer approved and fewer fatal injury claims compared with units with less volume. The findings support the development towards consolidation of units in Denmark. A suggested option would be to tailor obstetric patient safety initiatives according to the delivery volume of individual labor units. © 2015 Nordic Federation of Societies of Obstetrics and Gynecology.

  4. Evaluation of SIR-A space radar for geologic interpretation: United States, Panama, Colombia, and New Guinea

    NASA Technical Reports Server (NTRS)

    Macdonald, H.; Waite, W. P.; Kaupp, V. H.; Bridges, L. C.; Storm, M.

    1983-01-01

    Comparisons between LANDSAT MSS imagery, and aircraft and space radar imagery from different geologic environments in the United States, Panama, Colombia, and New Guinea demonstrate the interdependence of radar system geometry and terrain configuration for optimum retrieval of geologic information. Illustrations suggest that in the case of space radars (SIR-A in particular), the ability to acquire multiple look-angle/look-direction radar images of a given area is more valuable for landform mapping than further improvements in spatial resolution. Radar look-angle is concluded to be one of the most important system parameters of a space radar designed to be used for geologic reconnaissance mapping. The optimum set of system parameters must be determined for imaging different classes of landform features and tailoring the look-angle to local topography.

  5. Evaluating Psychosocial and Behavioral Mechanisms of Change in a Tailored Communication Intervention

    ERIC Educational Resources Information Center

    Elder, John P.; Ayala, Guadalupe X.; Slymen, Donald J.; Arredondo, Elva M.; Campbell, Nadia R.

    2009-01-01

    This study examined the impact of a tailored nutrition intervention at 3 and 6 months postintervention. In all, 357 Latinas were randomly assigned to one of three conditions: (1) a control condition comprised of previously developed Spanish language targeted materials, (2) tailored print materials, or (3) tailored print materials accompanied by…

  6. A Comparison of a Bayesian and a Maximum Likelihood Tailored Testing Procedure.

    ERIC Educational Resources Information Center

    McKinley, Robert L.; Reckase, Mark D.

    A study was conducted to compare tailored testing procedures based on a Bayesian ability estimation technique and on a maximum likelihood ability estimation technique. The Bayesian tailored testing procedure selected items so as to minimize the posterior variance of the ability estimate distribution, while the maximum likelihood tailored testing…

  7. Computer-Supported Feedback Message Tailoring for Healthcare Providers in Malawi: Proof-of-Concept.

    PubMed

    Landis-Lewis, Zach; Douglas, Gerald P; Hochheiser, Harry; Kam, Matthew; Gadabu, Oliver; Bwanali, Mwatha; Jacobson, Rebecca S

    2015-01-01

    Although performance feedback has the potential to help clinicians improve the quality and safety of care, healthcare organizations generally lack knowledge about how this guidance is best provided. In low-resource settings, tools for theory-informed feedback tailoring may enhance limited clinical supervision resources. Our objectives were to establish proof-of-concept for computer-supported feedback message tailoring in Malawi, Africa. We conducted this research in five stages: clinical performance measurement, modeling the influence of feedback on antiretroviral therapy (ART) performance, creating a rule-based message tailoring process, generating tailored messages for recipients, and finally analysis of performance and message tailoring data. We retrospectively generated tailored messages for 7,448 monthly performance reports from 11 ART clinics. We found that tailored feedback could be routinely generated for four guideline-based performance indicators, with 35% of reports having messages prioritized to optimize the effect of feedback. This research establishes proof-of-concept for a novel approach to improving the use of clinical performance feedback in low-resource settings and suggests possible directions for prospective evaluations comparing alternative designs of feedback messages.

  8. A Randomized Controlled Trial of a Tailored Interactive Computer-Delivered Intervention to Promote Colorectal Cancer Screening: Sometimes More is Just the Same

    PubMed Central

    Bartholomew, Leona K.; McQueen, Amy; Bettencourt, Judy L.; Greisinger, Anthony; Coan, Sharon P.; Lairson, David; Chan, Wenyaw; Hawley, S. T.; Myers, R. E.

    2012-01-01

    Background There have been few studies of tailored interventions to promote colorectal cancer (CRC) screening. Purpose We conducted a randomized trial of a tailored, interactive intervention to increase CRC screening. Methods Patients 50–70 years completed a baseline survey, were randomized to one of three groups, and attended a wellness exam after being exposed to a tailored intervention about CRC screening (tailored group), a public web site about CRC screening (web site group), or no intervention (survey-only group). The primary outcome was completion of any recommended CRC screening by 6 months. Results There was no statistically significant difference in screening by 6 months: 30%, 31%, and 28% of the survey-only, web site, and tailored groups were screened. Exposure to the tailored intervention was associated with increased knowledge and CRC screening self-efficacy at 2 weeks and 6 months. Family history, prior screening, stage of change, and physician recommendation moderated the intervention effects. Conclusions A tailored intervention was not more effective at increasing screening than a public web site or only being surveyed. PMID:21271365

  9. Extracting laboratory test information from biomedical text

    PubMed Central

    Kang, Yanna Shen; Kayaalp, Mehmet

    2013-01-01

    Background: No previous study reported the efficacy of current natural language processing (NLP) methods for extracting laboratory test information from narrative documents. This study investigates the pathology informatics question of how accurately such information can be extracted from text with the current tools and techniques, especially machine learning and symbolic NLP methods. The study data came from a text corpus maintained by the U.S. Food and Drug Administration, containing a rich set of information on laboratory tests and test devices. Methods: The authors developed a symbolic information extraction (SIE) system to extract device and test specific information about four types of laboratory test entities: Specimens, analytes, units of measures and detection limits. They compared the performance of SIE and three prominent machine learning based NLP systems, LingPipe, GATE and BANNER, each implementing a distinct supervised machine learning method, hidden Markov models, support vector machines and conditional random fields, respectively. Results: Machine learning systems recognized laboratory test entities with moderately high recall, but low precision rates. Their recall rates were relatively higher when the number of distinct entity values (e.g., the spectrum of specimens) was very limited or when lexical morphology of the entity was distinctive (as in units of measures), yet SIE outperformed them with statistically significant margins on extracting specimen, analyte and detection limit information in both precision and F-measure. Its high recall performance was statistically significant on analyte information extraction. Conclusions: Despite its shortcomings against machine learning methods, a well-tailored symbolic system may better discern relevancy among a pile of information of the same type and may outperform a machine learning system by tapping into lexically non-local contextual information such as the document structure. PMID:24083058

  10. Vegetation growth enhancement in urban environments of the Conterminous United States.

    PubMed

    Jia, Wenxiao; Zhao, Shuqing; Liu, Shuguang

    2018-05-19

    Cities are natural laboratories for studying vegetation responses to global environmental changes because of their climate, atmospheric, and biogeochemical conditions. However, few holistic studies have been conducted on the impact of urbanization on vegetation growth. We decomposed the overall impacts of urbanization on vegetation growth into direct (replacement of original land surfaces by impervious built-up) and indirect (urban environments) components, using a conceptual framework and remotely-sensed data for 377 metropolitan statistical areas (MSAs) in the conterminous United States (CONUS) in 2001, 2006, and 2011. Results showed that urban pixels are often greener than expected given the amount of paved surface they contain. The vegetation growth enhancement due to indirect effects occurred in 88.4%, 90.8% and 92.9% of urban bins in 2001, 2006 and 2011, respectively. By defining offset value as the ratio of the absolute indirect and direct impact, we obtained that growth enhancement due to indirect effects compensated for about 29.2%, 29.5% and 31.0% of the reduced productivity due to loss of vegetated surface area on average in 2001, 2006, and 2011, respectively. Vegetation growth responses to urbanization showed little temporal variation but large regional differences with higher offset value in the western CONUS than in the eastern CONUS. Our study highlights the prevalence of vegetation growth enhancement in urban environments and the necessity of differentiating various impacts of urbanization on vegetation growth, and calls for tailored field experiments to understand the relative contributions of various driving forces to vegetation growth and predict vegetation responses to future global change using cities as harbingers. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  11. A model of tailoring effects: A randomized controlled trial examining the mechanisms of tailoring in a web-based STD screening intervention.

    PubMed

    Lustria, Mia Liza A; Cortese, Juliann; Gerend, Mary A; Schmitt, Karla; Kung, Ying Mai; McLaughlin, Casey

    2016-11-01

    This study explores the mechanisms of tailoring within the context of RU@Risk a brief Web-based intervention designed to promote sexually transmitted disease (STD) testing among young adults. This is one of a few studies to empirically examine theorized message processing mechanisms of tailoring and persuasion outcomes in a single model. Sexually active college students (N = 1065) completed a pretest, were randomly assigned to explore a tailored or nontailored website, completed a posttest, and were offered the opportunity to order a free at-home STD test kit. As intervention effects were hypothesized to work via increases in perceived risk, change in perceived risk from pretest to posttest by condition was examined. Hypothesized mechanisms of tailoring (perceived personal relevance, attention, and elaboration) were examined using structural equation modeling (SEM). All analyses controlled for demographic variables and sexual history. As predicted, perceived risk of STDs increased from pretest to posttest, but only in the tailored condition. Results revealed that exposure to the tailored (vs. nontailored) website increased perceived personal relevance, attention to, and elaboration of the message. These effects in turn were associated with greater perceived risk of STDs and intentions to get tested. Additionally, participants in the tailored condition were more likely to order a test kit. Findings provide insight into the mechanisms of tailoring with important implications for optimizing message design. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  12. Effectiveness of different methods for delivering tailored nutrition education to low income, ethnically diverse adults

    PubMed Central

    Gans, Kim M; Risica, Patricia M; Strolla, Leslie O; Fournier, Leanne; Kirtania, Usree; Upegui, David; Zhao, Julie; George, Tiffiney; Acharyya, Suddhasatta

    2009-01-01

    Background Computer-tailored written nutrition interventions have been shown to be more effective than non-tailored materials in changing diet, but continued research is needed. Your Healthy Life/Su Vida Saludable (YHL-SVS) was an intervention study with low income, ethnically diverse, English and Spanish-speaking participants to determine which methods of delivering tailored written nutrition materials were most effective in lowering fat and increasing fruit and vegetable (F&V) intake. Methods YHL-SVS was a randomized controlled trial with four experimental conditions: 1) Nontailored (NT) comparison group; 2) Single Tailored (ST) packet; 3) Multiple Tailored (MT) packet mailed in four installments; 4) Multiple Re-Tailored (MRT) MT packets re-tailored between mailings via brief phone surveys. A baseline telephone survey collected information for tailoring as well as evaluation. Follow-up evaluation surveys were collected 4- and 7-months later. Primary outcomes included F&V intake and fat related behaviors. Descriptive statistics, paired t-test and ANOVA were used to examine the effectiveness of different methods of delivering tailored nutrition information. Results Both the ST and MT groups reported significantly higher F&V intake at 4-months than the NT and MRT groups. At 7 months, only the MT group still had significantly higher F&V intake compared to the NT group. For changes in fat-related behaviors, both the MT and MRT groups showed more change than NT at 4 months, but at 7 months, while these differences persisted, they were no longer statistically significant. There was a significant interaction of experimental group by education for change in F&V intake (P = .0085) with the lowest educational group demonstrating the most change. Conclusion In this study, tailored interventions were more effective than non-tailored interventions in improving the short-term dietary behaviors of low income, ethnically diverse participants. Delivery of information in multiple smaller doses over time appeared to improve effectiveness. Future studies should determine which variables are mediators of dietary change and whether these differ by participant demographics. Moreover, future research should differentiate the effects of tailoring vs. cultural adaptation in ethnically diverse populations and study the dissemination of tailored interventions into community-based settings. Trial registration Current Controlled Trials # NCT00301691. PMID:19416525

  13. Application of telecom planar lightwave circuits for homeland security sensing

    NASA Astrophysics Data System (ADS)

    Veldhuis, Gert J.; Elders, Job; van Weerden, Harm; Amersfoort, Martin

    2004-03-01

    Over the past decade, a massive effort has been made in the development of planar lightwave circuits (PLCs) for application in optical telecommunications. Major advances have been made, on both the technological and functional performance front. Highly sophisticated software tools that are used to tailor designs to required functional performance support these developments. In addition extensive know-how in the field of packaging, testing, and failure mode and effects analysis (FMEA) has been built up in the struggle for meeting the stringent Telcordia requirements that apply to telecom products. As an example, silica-on-silicon is now a mature technology available at several industrial foundries around the world, where, on the performance front, the arrayed-waveguide grating (AWG) has evolved into an off-the-shelf product. The field of optical chemical-biological (CB) sensors for homeland security application can greatly benefit from the advances as described above. In this paper we discuss the currently available technologies, device concepts, and modeling tools that have emerged from the telecommunications arena and that can effectively be applied to the field of homeland security. Using this profound telecom knowledge base, standard telecom components can readily be tailored for detecting CB agents. Designs for telecom components aim at complete isolation from the environment to exclude impact of environmental parameters on optical performance. For sensing applications, the optical path must be exposed to the measurand, in this area additional development is required beyond what has already been achieved in telecom development. We have tackled this problem, and are now in a position to apply standard telecom components for CB sensing. As an example, the application of an AWG as a refractometer is demonstrated, and its performance evaluated.

  14. Web-Based Video-Coaching to Assist an Automated Computer-Tailored Physical Activity Intervention for Inactive Adults: A Randomized Controlled Trial.

    PubMed

    Alley, Stephanie; Jennings, Cally; Plotnikoff, Ronald C; Vandelanotte, Corneel

    2016-08-12

    Web-based physical activity interventions that apply computer tailoring have shown to improve engagement and behavioral outcomes but provide limited accountability and social support for participants. It is unknown how video calls with a behavioral expert in a Web-based intervention will be received and whether they improve the effectiveness of computer-tailored advice. The purpose of this study was to determine the feasibility and effectiveness of brief video-based coaching in addition to fully automated computer-tailored advice in a Web-based physical activity intervention for inactive adults. Participants were assigned to one of the three groups: (1) tailoring + video-coaching where participants received an 8-week computer-tailored Web-based physical activity intervention ("My Activity Coach") including 4 10-minute coaching sessions with a behavioral expert using a Web-based video-calling program (eg, Skype; n=52); (2) tailoring-only where participants received the same intervention without the coaching sessions (n=54); and (3) a waitlist control group (n=45). Demographics were measured at baseline, intervention satisfaction at week 9, and physical activity at baseline, week 9, and 6 months by Web-based self-report surveys. Feasibility was analyzed by comparing intervention groups on retention, adherence, engagement, and satisfaction using t tests and chi-square tests. Effectiveness was assessed using linear mixed models to compare physical activity changes between groups. A total of 23 tailoring + video-coaching participants, 30 tailoring-only participants, and 30 control participants completed the postintervention survey (83/151, 55.0% retention). A low percentage of tailoring + video-coaching completers participated in the coaching calls (11/23, 48%). However, the majority of those who participated in the video calls were satisfied with them (5/8, 71%) and had improved intervention adherence (9/11, 82% completed 3 or 4 modules vs 18/42, 43%, P=.01) and engagement (110 minutes spent on the website vs 78 minutes, P=.02) compared with other participants. There were no overall retention, adherence, engagement, and satisfaction differences between tailoring + video-coaching and tailoring-only participants. At 9 weeks, physical activity increased from baseline to postintervention in all groups (tailoring + video-coaching: +150 minutes/week; tailoring only: +123 minutes/week; waitlist control: +34 minutes/week). The increase was significantly higher in the tailoring + video-coaching group compared with the control group (P=.01). No significant difference was found between intervention groups and no significant between-group differences were found for physical activity change at 6 months. Only small improvements were observed when video-coaching was added to computer-tailored advice in a Web-based physical activity intervention. However, combined Web-based video-coaching and computer-tailored advice was effective in comparison with a control group. More research is needed to determine whether Web-based coaching is more effective than stand-alone computer-tailored advice. Australian New Zealand Clinical Trials Registry (ACTRN): 12614000339651; http://www.anzctr.org.au/TrialSearch.aspx?searchTxt=ACTRN12614000339651+&isBasic=True (Archived by WebCite at http://www.webcitation.org/6jTnOv0Ld).

  15. Web-Based Video-Coaching to Assist an Automated Computer-Tailored Physical Activity Intervention for Inactive Adults: A Randomized Controlled Trial

    PubMed Central

    Jennings, Cally; Plotnikoff, Ronald C; Vandelanotte, Corneel

    2016-01-01

    Background Web-based physical activity interventions that apply computer tailoring have shown to improve engagement and behavioral outcomes but provide limited accountability and social support for participants. It is unknown how video calls with a behavioral expert in a Web-based intervention will be received and whether they improve the effectiveness of computer-tailored advice. Objective The purpose of this study was to determine the feasibility and effectiveness of brief video-based coaching in addition to fully automated computer-tailored advice in a Web-based physical activity intervention for inactive adults. Methods Participants were assigned to one of the three groups: (1) tailoring + video-coaching where participants received an 8-week computer-tailored Web-based physical activity intervention (“My Activity Coach”) including 4 10-minute coaching sessions with a behavioral expert using a Web-based video-calling program (eg, Skype; n=52); (2) tailoring-only where participants received the same intervention without the coaching sessions (n=54); and (3) a waitlist control group (n=45). Demographics were measured at baseline, intervention satisfaction at week 9, and physical activity at baseline, week 9, and 6 months by Web-based self-report surveys. Feasibility was analyzed by comparing intervention groups on retention, adherence, engagement, and satisfaction using t tests and chi-square tests. Effectiveness was assessed using linear mixed models to compare physical activity changes between groups. Results A total of 23 tailoring + video-coaching participants, 30 tailoring-only participants, and 30 control participants completed the postintervention survey (83/151, 55.0% retention). A low percentage of tailoring + video-coaching completers participated in the coaching calls (11/23, 48%). However, the majority of those who participated in the video calls were satisfied with them (5/8, 71%) and had improved intervention adherence (9/11, 82% completed 3 or 4 modules vs 18/42, 43%, P=.01) and engagement (110 minutes spent on the website vs 78 minutes, P=.02) compared with other participants. There were no overall retention, adherence, engagement, and satisfaction differences between tailoring + video-coaching and tailoring-only participants. At 9 weeks, physical activity increased from baseline to postintervention in all groups (tailoring + video-coaching: +150 minutes/week; tailoring only: +123 minutes/week; waitlist control: +34 minutes/week). The increase was significantly higher in the tailoring + video-coaching group compared with the control group (P=.01). No significant difference was found between intervention groups and no significant between-group differences were found for physical activity change at 6 months. Conclusions Only small improvements were observed when video-coaching was added to computer-tailored advice in a Web-based physical activity intervention. However, combined Web-based video-coaching and computer-tailored advice was effective in comparison with a control group. More research is needed to determine whether Web-based coaching is more effective than stand-alone computer-tailored advice. Trial Registration Australian New Zealand Clinical Trials Registry (ACTRN): 12614000339651; http://www.anzctr.org.au/TrialSearch.aspx?searchTxt=ACTRN12614000339651+&isBasic=True (Archived by WebCite at http://www.webcitation.org/6jTnOv0Ld) PMID:27520283

  16. Theory-and evidence-based development and process evaluation of the Move More for Life program: a tailored-print intervention designed to promote physical activity among post-treatment breast cancer survivors

    PubMed Central

    2013-01-01

    Objective Several physical activity interventions have been effective in improving the health outcomes of breast cancer survivors. However, few interventions have provided detailed descriptions regarding how such interventions work. To develop evidence-based practice in this field, detailed descriptions of intervention development and delivery is needed. This paper aims to (1) describe the theory-and evidence-based development of the Move More for Life program, a physical activity program for breast cancer survivors; and (2) serve as an exemplar for theory-based applied research. Method The program-planning model outlined by Kreuter and colleagues was used to develop the computer-tailored intervention. Results The tailoring guide developed by Kreuter and colleagues served as a useful program planning tool in terms of integrating theory and evidence-based best practice into intervention strategies. Overall, participants rated the intervention positively, with the majority reporting that the tailored materials caught their attention, were personally relevant to them, and were useful for helping them to change their behaviour. However, there was considerable room for improvement. Conclusion The Move More for Life program is an example of a theory-based, low-cost and potentially sustainable strategy to physical activity promotion and may stand as an exemplar for Social Cognitive Theory-based applied research. By providing a detailed description of the development of the Move More for Life program, a critical evaluation of the working mechanisms of the intervention is possible, and will guide researchers in the replication or adaption and re-application of the specified techniques. This has potential implications for researchers examining physical activity promotion among cancer survivors and for researchers exploring distance-based physical activity promotion techniques among other populations. Trial registrations Australian New Zealand Clinical Trials Registry (ANZCTR) identifier: ACTRN12611001061921. PMID:24192320

  17. Challenges in treatment of posttraumatic stress disorder in refugees: towards integration of evidence-based treatments with contextual and culture-sensitive perspectives

    PubMed Central

    Drožđek, Boris

    2015-01-01

    Background Research shows that trauma-focused therapy and multimodal interventions are the two most often used strategies in treatment of refugees suffering from posttraumatic stress disorder (PTSD). While preliminary evidence suggests that trauma-focused approaches may have some efficacy, this could not be established for multimodal interventions. However, it may be that multimodal interventions have been studied in more treatment-resistant refugees with very high levels of psychopathology, disability, and chronicity. In the past decades, various models for understanding of the complex relationship between mental health problems and well-being have emerged. They aim at framing mental health problems in individualized, contextual, epigenetic, and culturally sensitive ways, and may be useful in tailoring content and timing of multimodal interventions. Objective To draw clinicians’ attention to the possibility of using the Integrative Contextual Model for understanding and assessment of posttrauma mental health sequelae while tailoring multimodal interventions; to present a possible way of combining multimodal with evidence-based trauma-focused approaches; and to improve the understanding and treatment of PTSD and other mental health problems in refugee survivors of prolonged and repeated trauma. Method Based on literature, clinical experience, and presentation of a fictional case, the use of the Integrative Contextual Model in tailoring the treatment of severe PTSD in a refugee patient is presented and discussed. Results The Integrative Contextual Model for understanding and assessing factors, which may play a role in causing and maintaining of PTSD and comorbidity in refugees, may help tailoring of multimodal interventions. These interventions can be combined with evidence-based trauma-focused treatments. Conclusion The field of refugee mental health intervention and clinical practice with traumatized refugees may be enriched with the use of contextual and developmental models for assessment and conceptualization of posttrauma sequelae. Multimodal and trauma-focused interventions may be applied sequentially in a course of the treatment trajectory. PMID:25573504

  18. The Role of eHealth in Optimizing Preventive Care in the Primary Care Setting.

    PubMed

    Carey, Mariko; Noble, Natasha; Mansfield, Elise; Waller, Amy; Henskens, Frans; Sanson-Fisher, Rob

    2015-05-22

    Modifiable health risk behaviors such as smoking, overweight and obesity, risky alcohol consumption, physical inactivity, and poor nutrition contribute to a substantial proportion of the world's morbidity and mortality burden. General practitioners (GPs) play a key role in identifying and managing modifiable health risk behaviors. However, these are often underdetected and undermanaged in the primary care setting. We describe the potential of eHealth to help patients and GPs to overcome some of the barriers to managing health risk behaviors. In particular, we discuss (1) the role of eHealth in facilitating routine collection of patient-reported data on lifestyle risk factors, and (2) the role of eHealth in improving clinical management of identified risk factors through provision of tailored feedback, point-of-care reminders, tailored educational materials, and referral to online self-management programs. Strategies to harness the capacity of the eHealth medium, including the use of dynamic features and tailoring to help end users engage with, understand, and apply information need to be considered and maximized. Finally, the potential challenges in implementing eHealth solutions in the primary care setting are discussed. In conclusion, there is significant potential for innovative eHealth solutions to make a contribution to improving preventive care in the primary care setting. However, attention to issues such as data security and designing eHealth interfaces that maximize engagement from end users will be important to moving this field forward.

  19. Effect of a Quality Improvement Program to Improve Guideline Adherence and Attainment of Clinical Standards in Dialysis Care: Report of Outcomes in Year 1.

    PubMed

    Youssouf, Sajeda; Nache, Azri; Wijesekara, Chandrakumaran; Middleton, Rachel J; Lewis, David; Shurrab, Aladdin E; O'Riordan, Edmond; Lappin, Lesley P; O'Donoghue, Donal; Kalra, Philip A; Hegarty, Janet

    2017-01-01

    Best practice in dialysis is synthesised in clear international guidelines. However, a large gap remains between the international guidelines and the actual delivery of care. In this paper, we report outcomes for the first year of a multifaceted dialysis improvement programme in our network. One year collaborative involving 3 haemodialysis units and a peritoneal dialysis (PD) programme involving 299 dialysis patients. Each unit addressed a different indicator (unit A - catheter-related bloodstream infection [CRBSI], unit B - pre-dialysis blood pressure [BP], unit C - dialysis dose, unit D - anaemia) with a shared aim to match the top 10% in the UK. Tailored multifaceted approaches include a modified collaborative methodology with an aim, framework, driver diagram, learning sessions, facilitated meetings, plan-do-study-act cycles and continuous measurement. Analysis of outcomes, costings, erythropoietin stimulating agent and iron use, and safety culture attributes. Unit A reduced CRBSI from 2.65 to 0.5 per 1,000 catheter days (p = 0.02). Unit B improved attainment of target BP from 37.5 to 67.2% (p = 0.003). Unit C improved attainment of target urea reduction ratio from 75.8 to 91.4% (p = 0.04). PD unit D improved attainment of target haemoglobin from 45.5 to 62.7% (p = 0.01), with no significant change in the indicators in a non-intervention unit. Safety culture attributes improved. Costs associated with admission for fluid overload and infection, erythropoietin, iron and thrombokinase use decreased 36% (£415,620-£264,143). Units that took part in this collaborative improved guideline adherence compared both to their own pre-intervention performance and a non-intervention unit. Such multifaceted interventions are a useful methodology to improve dialysis care. © 2017 S. Karger AG, Basel.

  20. The Matter in Extreme Conditions instrument at the Linac Coherent Light Source

    PubMed Central

    Nagler, Bob; Arnold, Brice; Bouchard, Gary; Boyce, Richard F.; Boyce, Richard M.; Callen, Alice; Campell, Marc; Curiel, Ruben; Galtier, Eric; Garofoli, Justin; Granados, Eduardo; Hastings, Jerry; Hays, Greg; Heimann, Philip; Lee, Richard W.; Milathianaki, Despina; Plummer, Lori; Schropp, Andreas; Wallace, Alex; Welch, Marc; White, William; Xing, Zhou; Yin, Jing; Young, James; Zastrau, Ulf; Lee, Hae Ja

    2015-01-01

    The LCLS beam provides revolutionary capabilities for studying the transient behavior of matter in extreme conditions. The particular strength of the Matter in Extreme Conditions instrument is that it combines the unique LCLS beam with high-power optical laser beams, and a suite of dedicated diagnostics tailored for this field of science. In this paper an overview of the beamline, the capabilities of the instrumentation, and selected highlights of experiments and commissioning results are presented. PMID:25931063

  1. Recent progress on improving ICRF coupling and reducing RF-specific impurities in ASDEX Upgrade

    NASA Astrophysics Data System (ADS)

    Zhang, Wei; Bobkov, Volodymyr; Noterdaeme, Jean-Marie; Tierens, Wouter; Aguiam, Diogo; Bilato, Roberto; Coster, David; Colas, Laurent; Crombé, Kristel; Fuenfgelder, Helmut; Faugel, Helmut; Feng, Yuhe; Jacquot, Jonathan; Jacquet, Philippe; Kallenbach, Arne; Kostic, Ana; Lunt, Tilmann; Maggiora, Riccardo; Ochoukov, Roman; Silva, Antonio; Suárez, Guillermo; Tuccilo, Angelo A.; Tudisco, Onofrio; Usoltceva, Mariia; Van Eester, Dirk; Wang, Yongsheng; Yang, Qingxi

    2017-10-01

    The recent scientific research on ASDEX Upgrade (AUG) has greatly advanced solutions to two issues of Radio Frequency (RF) heating in the Ion Cyclotron Range of Frequencies (ICRF): (a) the coupling of ICRF power to the plasma is significantly improved by density tailoring with local gas puffing; (b) the release of RF-specific impurities is significantly reduced by minimizing the RF near field with 3-strap antennas. This paper summarizes the applied methods and reviews the associated achievements.

  2. Simulations of laser undulators

    NASA Astrophysics Data System (ADS)

    Milton, S. V.; Biedron, S. B.; Einstein, J. E.

    2016-09-01

    We perform a series of single-pass, one-D free-electron laser simulations based on an electron beam from a standard linear accelerator coupled with a so-called laser undulator, a specialized device that is more compact than a standard undulator based on magnetic materials. The longitudinal field profiles of such lasers undulators are intriguing as one must and can tailor the profile for the needs of creating the virtual undulator. We present and discuss several results of recent simulations and our future steps.

  3. Radiation balances and the solar constant

    NASA Technical Reports Server (NTRS)

    Crommelynck, D.

    1981-01-01

    The radiometric concepts are defined in order to consider various types of radiation balances and relate them to the diabetic form of the energy balance. Variability in space and time of the components of the radiation field are presented. A specific concept for sweeping which is tailored to the requirements is proposed. Finally, after establishing the truncated character of the present knowledge of the radiation balance. The results of the last observations of the solar constant are given. Ground and satellite measurement techniques are discussed.

  4. Technical knowledge and skills development in the informal sector in Kenya: The case of custom tailors

    NASA Astrophysics Data System (ADS)

    Apunda, Edwinah Amondi; de Klerk, Helena M.; Ogina, Teresa

    2017-06-01

    Custom tailors working in the informal sector in Nairobi, Kenya, mainly acquire technical skills through undertaking traditional apprenticeships (TAs). However, most of these tailors are semi-skilled, produce low-quality products and are often poorer than their formally trained counterparts. This qualitative case study explores the aspects of technical skills and knowledge which tailoring apprentices develop, and the factors which influence these outcomes. The findings show that apprentices do acquire basic technical skills for immediate application to ongoing tailoring activities (such as how to take body measurements, draft patterns, and cut, sew and finish constructed garments). However, apprentices do not acquire the technical knowledge that underpins the trade. Most master tailors who have completed TAs lack technical knowledge and have no access to technical skills upgrading. This perpetuates the cycle of basic and limited technical skills transfer to apprentices, poor performance and poverty among tailors. Both apprentices and master tailors expressed concern over knowledge limitations in TAs and a need to access further training to improve skills and acquire knowledge of the trade. The authors of this article argue that, technically and pedagogically, skilled master tailors are critical to improving training quality. Complementary training in theoretical knowledge is also important in improving apprentices' technical skills and understanding of the trade. Inclusion of TAs in government policy may help ensure sustainable improvement of skills.

  5. The Effects of Tailoring Knowledge Acquisition on Colorectal Cancer Screening Self-Efficacy

    PubMed Central

    Jerant, Anthony; To, Patricia; Franks, Peter

    2015-01-01

    Interventions tailored to psychological factors such as personal and vicarious behavioral experiences can enhance behavioral self-efficacy, but are complex to develop and implement. Information seeking theory suggests tailoring acquisition of health knowledge (without concurrent psychological factor tailoring) could enhance self-efficacy, simplifying the design of tailored behavior change interventions. To begin to examine this issue, the authors conducted exploratory analyses of data from a randomized controlled trial, comparing the effects of an experimental colorectal cancer (CRC) screening intervention tailoring knowledge acquisition with the effects of a non-tailored control on CRC screening knowledge and self-efficacy in 1159 patients comprising three ethnicity/language strata (Hispanic/Spanish 23.4%, Hispanic/English 27.2%, non-Hispanic/English 49.3%) and five recruitment center strata. Adjusted for study strata, the mean post-intervention knowledge score was significantly higher in the experimental group versus control. Adjusted experimental intervention exposure (B = 0.22, 95% CI [0.14, 0.30]), pre-intervention knowledge (B = 0.11, 95% CI [0.05, 0.16]), and post-intervention knowledge (B = 0.03, 95% CI [0.01, 0.05]) were independently associated with subsequent CRC screening self-efficacy (p < .001 all associations). These exploratory findings suggest tailoring knowledge acquisition may enhance self-efficacy, with potential implications for tailored intervention design, but require confirmation in studies specifically designed to examine this issue. PMID:25928315

  6. Employee Perceptions of Workplace Health Promotion Programs: Comparison of a Tailored, Semi-Tailored, and Standardized Approach.

    PubMed

    Street, Tamara D; Lacey, Sarah J

    2018-04-28

    In the design of workplace health promotion programs (WHPPs), employee perceptions represent an integral variable which is predicted to translate into rate of user engagement (i.e., participation) and program loyalty. This study evaluated employee perceptions of three workplace health programs promoting nutritional consumption and physical activity. Programs included: (1) an individually tailored consultation with an exercise physiologist and dietitian; (2) a semi-tailored 12-week SMS health message program; and (3) a standardized group workshop delivered by an expert. Participating employees from a transport company completed program evaluation surveys rating the overall program, affect, and utility of: consultations ( n = 19); SMS program ( n = 234); and workshops ( n = 86). Overall, participants’ affect and utility evaluations were positive for all programs, with the greatest satisfaction being reported in the tailored individual consultation and standardized group workshop conditions. Furthermore, mode of delivery and the physical presence of an expert health practitioner was more influential than the degree to which the information was tailored to the individual. Thus, the synergy in ratings between individually tailored consultations and standardized group workshops indicates that low-cost delivery health programs may be as appealing to employees as tailored, and comparatively high-cost, program options.

  7. Comparing homeless persons' care experiences in tailored versus nontailored primary care programs.

    PubMed

    Kertesz, Stefan G; Holt, Cheryl L; Steward, Jocelyn L; Jones, Richard N; Roth, David L; Stringfellow, Erin; Gordon, Adam J; Kim, Theresa W; Austin, Erika L; Henry, Stephen Randal; Kay Johnson, N; Shanette Granstaff, U; O'Connell, James J; Golden, Joya F; Young, Alexander S; Davis, Lori L; Pollio, David E

    2013-12-01

    We compared homeless patients' experiences of care in health care organizations that differed in their degree of primary care design service tailoring. We surveyed homeless-experienced patients (either recently or currently homeless) at 3 Veterans Affairs (VA) mainstream primary care settings in Pennsylvania and Alabama, a homeless-tailored VA clinic in California, and a highly tailored non-VA Health Care for the Homeless Program in Massachusetts (January 2011-March 2012). We developed a survey, the "Primary Care Quality-Homeless Survey," to reflect the concerns and aspirations of homeless patients. Mean scores at the tailored non-VA site were superior to those from the 3 mainstream VA sites (P < .001). Adjusting for patient characteristics, these differences remained significant for subscales assessing the patient-clinician relationship (P < .001) and perceptions of cooperation among providers (P = .004). There were 1.5- to 3-fold increased odds of an unfavorable experience in the domains of the patient-clinician relationship, cooperation, and access or coordination for the mainstream VA sites compared with the tailored non-VA site; the tailored VA site attained intermediate results. Tailored primary care service design was associated with a superior service experience for patients who experienced homelessness.

  8. Public Housing: A Tailored Approach to Energy Retrofits

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dentz, J.; Conlin, F.; Podorson, D.

    2014-06-01

    Over one million HUD-supported public housing units provide rental housing for eligible low-income families across the country. A survey of over 100 PHAs across the country indicated that there is a high level of interest in developing low cost solutions that improve energy efficiency and can be seamlessly included in the refurbishment process. Further, PHAs, have incentives (both internal and external) to reduce utility bills. ARIES worked with two public housing authorities (PHAs) to develop packages of energy efficiency retrofit measures the PHAs can cost effectively implement with their own staffs in the normal course of housing operations at themore » time when units are refurbished between occupancies. The energy efficiency turnover protocols emphasized air infiltration reduction, duct sealing and measures that improve equipment efficiency. ARIES documented implementation in ten housing units. Reductions in average air leakage were 16-20% and duct leakage reductions averaged 38%. Total source energy consumption savings was estimated at 6-10% based on BEopt modeling with a simple payback of 1.7 to 2.2 years. Implementation challenges were encountered mainly related to required operational changes and budgetary constraints. Nevertheless, simple measures can feasibly be accomplished by PHA staff at low or no cost. At typical housing unit turnover rates, these measures could impact hundreds of thousands of unit per year nationally.« less

  9. Context, confidentiality, and consent in tailored health communications: a cautionary note.

    PubMed

    Orleans, C T

    1999-01-01

    This article highlights key contextual factors that emerge when the evolution of tailored health communications is viewed against the backdrop of dynamic changes in the nation's health care system--including the shift from fee-for-service medicine to managed care and the proliferation of direct-to-consumer and tailored marketing strategies in the pharmaceutical industry. It focuses on contextual variables with potential to significantly mediate the impact of personally tailored health advice--including those related to confidentiality, privacy, and informed consent and to the perceived aims, intents, and sources of tailored health messages. To protect the future of tailored health messages, more research attention must be given to defining these contextual factors and understanding the roles that they play and the ways in which they can be controlled to assure the best outcomes. Such research could point the way towards a set of empirical and ethical "best practices" based on a scientific understanding of how to maximize the benefits, and minimize the potential harms, of the widescale use of tailored health communications.

  10. Differences in use and impact of computer-tailored dietary fat-feedback according to stage of change and education.

    PubMed

    Brug, J; van Assema, P

    2000-06-01

    Computer-tailored written nutrition education has been found to be more effective in motivating people to reduce their consumption of fat than traditional written information. The present study aimed to test whether this innovative nutrition education intervention is also suitable for people with low motivation to change and low education among a self-selected sample of 699 adults. Computer-tailored feedback proved to be more effective in motivating precontemplators to proceed towards fat reduction than general information. Higher appreciation and use of the computer-tailored fat-feedback was found among respondents in contemplation than in other stages. No difference in impact of computer-tailored fat-feedback on fat intake was found between educational groups. Respondents with low education were more positive about how interesting and how personally relevant the tailored letters were. It was concluded that printed computer-tailored fat-feedback can be applied successfully to motivate precontemplators and people with low education to (consider to) reduce their fat intake.

  11. Study plan to identify long term national telecommunications need and priorities applying Delphi techniques (handbook). [technological forecasting - United States of America

    NASA Technical Reports Server (NTRS)

    1974-01-01

    A handbook that explains the basic Delphi methodology and discusses modified Delphi techniques is presented. The selection of communications experts to participate in a study, the construction of questionnaires on potential communications developments, and requisite technology is treated. No two modified Delphi studies were the same, which reflects the flexibility and adaptability of the technique. Each study must be specifically tailored to a particular case, and consists of seeking a consensus of opinion among experts about a particular subject and attendant conditions that may prevail in the future.

  12. Process, not product: investigating recommendations for improving citizen science "success".

    PubMed

    Freitag, Amy; Pfeffer, Max J

    2013-01-01

    Citizen science programs are increasingly popular for a variety of reasons, from public education to new opportunities for data collection. The literature published in scientific journals resulting from these projects represents a particular perspective on the process. These articles often conclude with recommendations for increasing "success". This study compared these recommendations to those elicited during interviews with program coordinators for programs within the United States. From this comparison, success cannot be unilaterally defined and therefore recommendations vary by perspective on success. Program coordinators tended to have more locally-tailored recommendations specific to particular aspects of their program mission.

  13. Mesoscale Modeling of Chromatin Folding

    NASA Astrophysics Data System (ADS)

    Schlick, Tamar

    2009-03-01

    Eukaryotic chromatin is the fundamental protein/nucleic acid unit that stores the genetic material. Understanding how chromatin fibers fold and unfold in physiological conditions is important for interpreting fundamental biological processes like DNA replication and transcription regulation. Using a mesoscopic model of oligonucleosome chains and tailored sampling protocols, we elucidate the energetics of oligonucleosome folding/unfolding and the role of each histone tail, linker histones, and divalent ions in regulating chromatin structure. The resulting compact topologies reconcile features of the zigzag model with straight linker DNAs with the solenoid model with bent linker DNAs for optimal fiber organization and reveal dynamic and energetic aspects involved.

  14. Statement of Rear Admiral Nevin P. Carr, Jr., United States Navy Chief of Naval Research before the Terrorism, Unconventional Threats and Capabilities Subcommittee of the House Armed Services Committee on The Fiscal year 2011 Budget Request

    DTIC Science & Technology

    2010-03-23

    foundation of our S&T portfolio by developing a broad base of scientific knowledge from which INP, FNC, and quick reaction efforts are generated...optimally tailoring experiences, in real-time, to current cognitive and physiological states of the learner. A unique human systems design approach is...efforts include modeling human responses to blast, ballistic, and blunt trauma, as well as modeling physical and cognitive effects of blast exposure and

  15. Economics of utilization of high sulfur coal resources - an integrated market approach

    USGS Publications Warehouse

    Bhagwat, S.B.

    1993-01-01

    Before the Clean Air Act Amendments of 1990, coal policies - especially coal research policies - were geared to find a solution to the sulfur emission problem. However, technologies to reduce sulfur emissions cannot be tailored for a single coal. A technology that will clean Illinois coal to compliance levels will do the same, or nearly the same, for most other types of coal. This paper will discuss an integrated approach to the analysis of the future of coals from different regions in the United States and its implications for coal-related policies by government and industry.

  16. Effect of Blended Feedstock on Pyrolysis Oil Composition

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Smith, Kristin M; Gaston, Katherine R

    Current techno-economic analysis results indicate biomass feedstock cost represents 27% of the overall minimum fuel selling price for biofuels produced from fast pyrolysis followed by hydrotreating (hydro-deoxygenation, HDO). As a result, blended feedstocks have been proposed as a way to both reduce cost as well as tailor key chemistry for improved fuel quality. For this study, two feedstocks were provided by Idaho National Laboratory (INL). Both were pyrolyzed and collected under the same conditions in the National Renewable Energy Laboratory's (NREL) Thermochemical Process Development Unit (TCPDU). The resulting oil properties were then analyzed and characterized for statistical differences.

  17. Why are Tailored Messages More Effective? A Multiple Mediation Analysis of a Breast Cancer Screening Intervention.

    PubMed

    Jensen, Jakob D; King, Andy J; Carcioppolo, Nicholas; Davis, LaShara

    2012-10-01

    Past research has found that tailoring increases the persuasive effectiveness of a message. However, the observed effect has been small and the explanatory mechanism remains unknown. To address these shortcomings, a tailoring software program was created that personalized breast cancer screening pamphlets according to risk, health belief model constructs, and visual preference. Women aged 40 and older ( N = 119) participated in a 2 (tailored vs. stock message) × 2 (charts/graphs vs. illustrated visuals) × 3 (nested replications of the visuals) experiment. Participants provided with tailored illustrated pamphlets expressed greater breast cancer screening intentions than those provided with other pamphlets. In a test of 10 different mediators, perceived message relevance was found to fully mediate the tailoring × visual interaction.

  18. STRATEGIES FOR OVERCOMING SITE AND RECRUITMENT CHALLENGES IN RESEARCH STUDIES BASED IN INTENSIVE CARE UNITS

    PubMed Central

    Chlan, Linda; Guttormson, Jill; Tracy, Mary Fran; Bremer, Karin Lindstrom

    2009-01-01

    Although enrolling a sufficient number of participants is a challenge for any multisite clinical trial, recruiting patients who are critically ill and receiving mechanical ventilatory support presents additional challenges because of the severity of the patients’ illness and the impediments to their communication. Recruitment challenges related to the research sites, nursing staff, and research participants faced in the first 2 years of a 4-year multisite clinical trial of a patient-directed music intervention for managing anxiety in the intensive care unit were determined. Strategies to overcome these challenges, and thereby increase enrollment, were devised. Individual strategies, such as timing of screening on a unit, were tailored to each participating site to enhance recruitment for this trial. Other strategies, such as obtaining a waiver for a participant’s signature, were instituted across all participating sites. Through implementation of these various strategies, the mean monthly enrollment of participants increased by 50%. Investigators are advised to plan well in advance of starting recruitment for a clinical trial based in an intensive care unit, anticipate peaks and valleys in recruitment, and be proactive in addressing issues creatively as the issues arise. PMID:19723861

  19. Coping with information style and family burden: Possible roles of self-stigma and hope among parents of children in a psychiatric inpatient unit.

    PubMed

    Hasson-Ohayon, I; Pijnenborg, G H M; Ben-Pazi, A; Taitel, S; Goldzweig, G

    2017-05-01

    Parents of children who are hospitalized in inpatient psychiatric units must cope with significant challenges. One of these challenges relates to the way in which they cope with illness-related information. The current study examined the relationship between two such coping styles - monitoring and blunting - and family burden among parents of children in a psychiatric inpatient unit. Moreover, the possible moderating roles played by hope and self-stigma in these associations were also examined. Questionnaires regarding coping with information style, self-stigma, hope and family burden were administered to 70 parents. A main positive effect of hope and a main negative effect of self-stigma were uncovered. An interaction between self-stigma and monitoring was also revealed, suggesting that for parents with high self-stigma, compared to those with low self-stigma, more monitoring was related to more burden. Tailoring family interventions according to coping style and self-stigma is highly recommended as a mean to reduce the family burden of parents whose child is hospitalized in a psychiatric inpatient unit. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

  20. Comparison of Diagnostic Accuracy between Octopus 900 and Goldmann Kinetic Visual Fields

    PubMed Central

    Rowe, Fiona J.; Rowlands, Alison

    2014-01-01

    Purpose. To determine diagnostic accuracy of kinetic visual field assessment by Octopus 900 perimetry compared with Goldmann perimetry. Methods. Prospective cross section evaluation of 40 control subjects with full visual fields and 50 patients with known visual field loss. Comparison of test duration and area measurement of isopters for Octopus 3, 5, and 10°/sec stimulus speeds. Comparison of test duration and type of visual field classification for Octopus versus Goldmann perimetry. Results were independently graded for presence/absence of field defect and for type and location of defect. Statistical evaluation comprised of ANOVA and paired t test for evaluation of parametric data with Bonferroni adjustment. Bland Altman and Kappa tests were used for measurement of agreement between data. Results. Octopus 5°/sec perimetry had comparable test duration to Goldmann perimetry. Octopus perimetry reliably detected type and location of visual field loss with visual fields matched to Goldmann results in 88.8% of results (K = 0.775). Conclusions. Kinetic perimetry requires individual tailoring to ensure accuracy. Octopus perimetry was reproducible for presence/absence of visual field defect. Our screening protocol when using Octopus perimetry is 5°/sec for determining boundaries of peripheral isopters and 3°/sec for blind spot mapping with further evaluation of area of field loss for defect depth and size. PMID:24587983

  1. The (cost-)effectiveness of an individually tailored long-term worksite health promotion programme on physical activity and nutrition: design of a pragmatic cluster randomised controlled trial

    PubMed Central

    Robroek, Suzan JW; Bredt, Folef J; Burdorf, Alex

    2007-01-01

    Background Cardiovascular disease is the leading cause of disability and mortality in most Western countries. The prevalence of several risk factors, most notably low physical activity and poor nutrition, is very high. Therefore, lifestyle behaviour changes are of great importance. The worksite offers an efficient structure to reach large groups and to make use of a natural social network. This study investigates a worksite health promotion programme with individually tailored advice in physical activity and nutrition and individual counselling to increase compliance with lifestyle recommendations and sustainability of a healthy lifestyle. Methods/Design The study is a pragmatic cluster randomised controlled trial with the worksite as the unit of randomisation. All workers will receive a standard worksite health promotion program. Additionally, the intervention group will receive access to an individual Health Portal consisting of four critical features: a computer-tailored advice, a monitoring function, a personal coach, and opportunities to contact professionals at request. Participants are employees working for companies in the Netherlands, being literate enough to read and understand simple Internet-based messages in the Dutch language. A questionnaire to assess primary outcomes (compliance with national recommendations on physical activity and on fruit and vegetable intake) will take place at baseline and after 12 and 24 months. This questionnaire also assesses secondary outcomes including fat intake, self-efficacy and self-perceived barriers on physical activity and fruit and vegetable intake. Other secondary outcomes, including a cardiovascular risk profile and physical fitness, will be measured at baseline and after 24 months. Apart from the effect evaluation, a process evaluation will be carried out to gain insight into participation and adherence to the worksite health promotion programme. A cost-effectiveness analysis and sensitivity analysis will be carried out as well. Discussion The unique combination of features makes the individually tailored worksite health promotion programme a promising tool for health promotion. It is hypothesized that the Health Portal's features will counteract loss to follow-up, and will increase compliance with the lifestyle recommendations and sustainability of a healthy lifestyle. Trial registration Current Controlled Trials ISRCTN52854353. PMID:17888161

  2. Tailored program evaluation: Past, present, future.

    PubMed

    Suggs, L Suzanne; Cowdery, Joan E; Carroll, Jennifer B

    2006-11-01

    This paper discusses measurement issues related to the evaluation of computer-tailored health behavior change programs. As the first generation of commercially available tailored products is utilized in health promotion programming, programmers and researchers are becoming aware of the unique challenges that the evaluation of these programs presents. A project is presented that used an online tailored health behavior assessment (HBA) in a worksite setting. Process and outcome evaluation methods are described and include the challenges faced, and strategies proposed and implemented, for meeting them. Implications for future research in tailored program development, implementation, and evaluation are also discussed.

  3. The unit field sanitation team: a square peg in a round hole.

    PubMed

    Bosetti, Timothy; Bridges, Davin

    2009-01-01

    Basic field sanitation and hygiene is a lost art in today's modern Army. Today, more than ever, there is a need for the unit field sanitation team (FST) to serve as advisors to unit commanders in the area of basic field sanitation and hygiene. Soldiers should know how to construct field latrines, construct waste disposal devices, conduct pest management and control activities, disinfect field water supplies, and practice personal hygiene under field conditions. The current unit FST concept is centered on company-sized formations operating in open terrain. This concept does not support current operations, transformed formations, rapidly changing doctrine, and the expeditionary nature of the Army. This article does not present a new concept, but rather a new look at an existing concept and practice based upon the lessons-learned and after-action reports from the Global War on Terrorism to support the Army in transformation during an era of persistent conflict.

  4. Magnetic nanoparticle drug delivery systems for targeting tumor

    NASA Astrophysics Data System (ADS)

    Mody, Vicky V.; Cox, Arthur; Shah, Samit; Singh, Ajay; Bevins, Wesley; Parihar, Harish

    2014-04-01

    Tumor hypoxia, or low oxygen concentration, is a result of disordered vasculature that lead to distinctive hypoxic microenvironments not found in normal tissues. Many traditional anti-cancer agents are not able to penetrate into these hypoxic zones, whereas, conventional cancer therapies that work by blocking cell division are not effective to treat tumors within hypoxic zones. Under these circumstances the use of magnetic nanoparticles as a drug delivering agent system under the influence of external magnetic field has received much attention, based on their simplicity, ease of preparation, and ability to tailor their properties for specific biological applications. Hence in this review article we have reviewed current magnetic drug delivery systems, along with their application and clinical status in the field of magnetic drug delivery.

  5. Tailoring of the Perpendicular Magnetization Component in Ferromagnetic Films on a Vicinal Substrate

    NASA Astrophysics Data System (ADS)

    Stupakiewicz, A.; Maziewski, A.; Matlak, K.; Spiridis, N.; Ślęzak, M.; Ślęzak, T.; Zajac, M.; Korecki, J.

    2008-11-01

    We have engineered the magnetic properties of 1 8 nm Co films epitaxially grown on an Au-buffered bifacial W(110)/W(540) single crystal. The surface of Au/W(110) was atomically flat, whereas the Au/W(540) followed the morphology of the vicinal W surface, showing a regular array of monoatomic steps. For Co grown on Au/W(540), the existence of the out-of-plane magnetization component extended strongly to a thickness d of about 8 nm, which was accompanied by an anomalous increase of the out-of-plane switching field with increasing d. In addition, the process of up-down magnetization switching could be realized with both a perpendicular and in-plane external magnetic field.

  6. The Role of Nonlinear Gradients in Parallel Imaging: A k-Space Based Analysis.

    PubMed

    Galiana, Gigi; Stockmann, Jason P; Tam, Leo; Peters, Dana; Tagare, Hemant; Constable, R Todd

    2012-09-01

    Sequences that encode the spatial information of an object using nonlinear gradient fields are a new frontier in MRI, with potential to provide lower peripheral nerve stimulation, windowed fields of view, tailored spatially-varying resolution, curved slices that mirror physiological geometry, and, most importantly, very fast parallel imaging with multichannel coils. The acceleration for multichannel images is generally explained by the fact that curvilinear gradient isocontours better complement the azimuthal spatial encoding provided by typical receiver arrays. However, the details of this complementarity have been more difficult to specify. We present a simple and intuitive framework for describing the mechanics of image formation with nonlinear gradients, and we use this framework to review some the main classes of nonlinear encoding schemes.

  7. Temperature and Microstructural Effects on the Superconducting Properties of Niobium Thin Films

    DOE PAGES

    Beebe, Melissa R.; Valente-Feliciano, Anne -Marie; Beringer, Douglas B.; ...

    2016-11-23

    Here, superconducting thin films have a wide range of dc and RF applications, from detectors to superconducting radio frequency. Amongst the most used materials, niobium (Nb) has the highest critical temperature (TC) and highest lower critical field (HC1) of the elemental superconductors and can be deposited on a variety of substrates, making Nb thin films very appealing for such applications. Here, we present temperature-dependent dc studies on the critical temperature and critical fields of Nb thin films grown on copper and r-plane sapphire surfaces. Additionally, we correlate the dc superconducting properties of these films with their microstructure, which allows formore » the possibility of tailoring future films for a specific application.« less

  8. Selective protected state preparation of coupled dissipative quantum emitters

    PubMed Central

    Plankensteiner, D.; Ostermann, L.; Ritsch, H.; Genes, C.

    2015-01-01

    Inherent binary or collective interactions in ensembles of quantum emitters induce a spread in the energy and lifetime of their eigenstates. While this typically causes fast decay and dephasing, in many cases certain special entangled collective states with minimal decay can be found, which possess ideal properties for spectroscopy, precision measurements or information storage. We show that for a specific choice of laser frequency, power and geometry or a suitable configuration of control fields one can efficiently prepare these states. We demonstrate this by studying preparation schemes for strongly subradiant entangled states of a chain of dipole-dipole coupled emitters. The prepared state fidelity and its entanglement depth is further improved via spatial excitation phase engineering or tailored magnetic fields. PMID:26549501

  9. van der Waals heterostructures of germanene, stanene, and silicene with hexagonal boron nitride and their topological domain walls

    NASA Astrophysics Data System (ADS)

    Wang, Maoyuan; Liu, Liping; Liu, Cheng-Cheng; Yao, Yugui

    2016-04-01

    We investigate van der Waals (vdW) heterostructures made of germanene, stanene, or silicene with hexagonal boron nitride (h-BN). The intriguing topological properties of these buckled honeycomb materials can be maintained and further engineered in the heterostructures, where the competition between the substrate effect and external electric fields can be used to control the tunable topological phase transitions. Using such heterostructures as building blocks, various vdW topological domain walls (DW) are designed, along which there exist valley polarized quantum spin Hall edge states or valley-contrasting edge states which are protected by valley(spin)- resolved topological charges and can be tailored by the patterning of the heterojunctions and by external fields.

  10. Piezoelectric effect on the thermal conductivity of monolayer gallium nitride

    NASA Astrophysics Data System (ADS)

    Zhang, Jin

    2018-01-01

    Using molecular dynamics and density functional theory simulations, in this work, we find that the heat transport property of the monolayer gallium nitride (GaN) can be efficiently tailored by external electric field due to its unique piezoelectric characteristic. As the monolayer GaN possesses different piezoelectric properties in armchair and zigzag directions, different effects of the external electric field on thermal conductivity are observed when it is applied in the armchair and zigzag directions. Our further study reveals that due to the elastoelectric effect in the monolayer GaN, the external electric field changes the Young's modulus and therefore changes the phonon group velocity. Also, due to the inverse piezoelectric effect, the applied electric field induces in-plane stress in the monolayer GaN subject to a length constraint, which results in the change in the lattice anharmonicity and therefore affects the phonon mean free path. Furthermore, for relatively long GaN monolayers, the in-plane stress may trigger the buckling instability, which can significantly reduce the phonon mean free path.

  11. Optical magnetic mirrors without metals

    DOE PAGES

    Liu, Sheng; Sinclair, Michael B.; Mahony, Thomas S.; ...

    2014-01-01

    The reflection of an optical wave from metal, arising from strong interactions between the optical electric field and the free carriers of the metal, is accompanied by a phase reversal of the reflected electric field. A far less common route to achieving high reflectivity exploits strong interactions between the material and the optical magnetic field to produce a “magnetic mirror” that does not reverse the phase of the reflected electric field. At optical frequencies, the magnetic properties required for strong interaction can be achieved only by using artificially tailored materials. Here, we experimentally demonstrate, for the first time to themore » best of our knowledge, the magnetic mirror behavior of a low-loss all-dielectric metasurface at infrared optical frequencies through direct measurements of the phase and amplitude of the reflected optical wave. The enhanced absorption and emission of transverse-electric dipoles placed close to magnetic mirrors can lead to exciting new advances in sensors, photodetectors, and light sources.« less

  12. Strong-field control and enhancement of chiral response in bi-elliptical high-order harmonic generation: an analytical model

    NASA Astrophysics Data System (ADS)

    Ayuso, David; Decleva, Piero; Patchkovskii, Serguei; Smirnova, Olga

    2018-06-01

    The generation of high-order harmonics in a medium of chiral molecules driven by intense bi-elliptical laser fields can lead to strong chiroptical response in a broad range of harmonic numbers and ellipticities (Ayuso et al 2018 J. Phys. B: At. Mol. Opt. Phys. 51 06LT01). Here we present a comprehensive analytical model that can describe the most relevant features arising in the high-order harmonic spectra of chiral molecules driven by strong bi-elliptical fields. Our model recovers the physical picture underlying chiral high-order harmonic generation (HHG) based on ultrafast chiral hole motion and identifies the rotationally invariant molecular pseudoscalars responsible for chiral dynamics. Using the chiral molecule propylene oxide as an example, we show that one can control and enhance the chiral response in bi-elliptical HHG by tailoring the driving field, in particular by tuning its frequency, intensity and ellipticity, exploiting a suppression mechanism of achiral background based on the linear Stark effect.

  13. How Smart are Smartphone Apps for Smoking Cessation? A Content Analysis.

    PubMed

    Hoeppner, Bettina B; Hoeppner, Susanne S; Seaboyer, Lourah; Schick, Melissa R; Wu, Gwyneth W Y; Bergman, Brandon G; Kelly, John F

    2016-05-01

    Smartphone technology is ideally suited to provide tailored smoking cessation support, yet it is unclear to what extent currently existing smartphone "apps" use tailoring, and if tailoring is related to app popularity and user-rated quality. We conducted a content analysis of Android smoking cessation apps (n = 225), downloaded between October 1, 2013 to May 31, 2014. We recorded app popularity (>10,000 downloads) and user-rated quality (number of stars) from Google Play, and coded the existence of tailoring features in the apps within the context of using the 5As ("ask," "advise," "assess," "assist," and "arrange follow-up"), as recommended by national clinical practice guidelines. Apps largely provided simplistic tools (eg, calculators, trackers), and used tailoring sparingly: on average, apps addressed 2.1 ± 0.9 of the 5As and used tailoring for 0.7 ± 0.9 of the 5As. Tailoring was positively related to app popularity and user-rated quality: apps that used two-way interactions (odds ratio [OR] = 5.56 [2.45-12.62]), proactive alerts (OR = 3.80 [1.54-9.38]), responsiveness to quit status (OR = 5.28 [2.18-12.79]), addressed more of the 5As (OR = 1.53 [1.10-2.14]), used tailoring for more As (OR = 1.67 [1.21-2.30]), and/or used more ways of tailoring 5As content (OR = 1.35 [1.13-1.62]) were more likely to be frequently downloaded. Higher star ratings were associated with a higher number of 5As addressed (b = 0.16 [0.03-0.30]), a higher number of 5As with any level of tailoring (b = 0.14 [0.01-0.27]), and a higher number of ways of tailoring 5As content (b = 0.08 [0.002-0.15]). Publically available smartphone smoking cessation apps are not particularly "smart": they commonly fall short of providing tailored feedback, despite users' preference for these features. © The Author 2015. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  14. How Smart are Smartphone Apps for Smoking Cessation? A Content Analysis

    PubMed Central

    Hoeppner, Susanne S.; Seaboyer, Lourah; Schick, Melissa R.; Wu, Gwyneth W. Y.; Bergman, Brandon G.; Kelly, John F.

    2016-01-01

    Abstract Introduction: Smartphone technology is ideally suited to provide tailored smoking cessation support, yet it is unclear to what extent currently existing smartphone “apps” use tailoring, and if tailoring is related to app popularity and user-rated quality. Methods: We conducted a content analysis of Android smoking cessation apps ( n = 225), downloaded between October 1, 2013 to May 31, 2014. We recorded app popularity (>10 000 downloads) and user-rated quality (number of stars) from Google Play, and coded the existence of tailoring features in the apps within the context of using the 5As (“ask,” “advise,” “assess,” “assist,” and “arrange follow-up”), as recommended by national clinical practice guidelines. Results: Apps largely provided simplistic tools (eg, calculators, trackers), and used tailoring sparingly: on average, apps addressed 2.1±0.9 of the 5As and used tailoring for 0.7±0.9 of the 5As. Tailoring was positively related to app popularity and user-rated quality: apps that used two-way interactions (odds ratio [ OR ] = 5.56 [2.45–12.62]), proactive alerts ( OR = 3.80 [1.54–9.38]), responsiveness to quit status ( OR = 5.28 [2.18–12.79]), addressed more of the 5As ( OR = 1.53 [1.10–2.14]), used tailoring for more As ( OR = 1.67 [1.21–2.30]), and/or used more ways of tailoring 5As content ( OR = 1.35 [1.13–1.62]) were more likely to be frequently downloaded. Higher star ratings were associated with a higher number of 5As addressed ( b = 0.16 [0.03–0.30]), a higher number of 5As with any level of tailoring ( b = 0.14 [0.01–0.27]), and a higher number of ways of tailoring 5As content ( b = 0.08 [0.002–0.15]). Conclusions: Publically available smartphone smoking cessation apps are not particularly “smart”: they commonly fall short of providing tailored feedback, despite users’ preference for these features. PMID:26045249

  15. Employment prospects and trends for gastroenterology trainees in Canada: A nationwide survey

    PubMed Central

    Razik, Roshan; Cino, Maria; Nguyen, Geoffrey C

    2013-01-01

    BACKGROUND: Many gastroenterology (GI) trainees face a variety of barriers to stable employment and are finding it increasingly difficult to secure employment in their chosen field. OBJECTIVE: To elucidate factors that contribute to the burden of unemployment and underemployment, and to examine solutions that may remedy this growing problem in the field of GI. METHODS: A nationwide survey of current, incoming and recently graduated individuals of GI training programs in Canada was conducted. Trainees in pediatric GI programs and those enrolled in sub-specialty programs within GI were also included. RESULTS: The response rate was 62%, with 93% of respondents enrolled in an adult GI training program. Many (73%) respondents planned to pursue further subspecialty training and the majority (53%) reported concerns regarding job security after graduation as contributory factors. Only 35% of respondents were confident that they would secure employment within six months of completing their training. Regarding barriers to employment, the most cited perceived reasons were lack of funding (both from hospitals and provincial governments) and senior physicians who continue to practice beyond retirement years. Sixty-nine per cent perceived a greater need for career guidance and 49% believed there were too many GI trainees relative to the current job market in their area. Most residents had a contingency plan if they remained unemployed >18 months, which often included moving to another province or to the United States. CONCLUSION: GI trainees throughout Canada reported substantial concerns about securing employment, citing national retirement trends and lack of funding as primary barriers to employment. Although these issues are not easily modifiable, certain problems should be targeted including optimizing training quotas, tailoring career guidance to the needs of the population, and emphasizing credentialing and quality control in endoscopy. PMID:24199210

  16. Imaging and controlling plasmonic interference fields at buried interfaces

    NASA Astrophysics Data System (ADS)

    Lummen, Tom T. A.; Lamb, Raymond J.; Berruto, Gabriele; Lagrange, Thomas; Dal Negro, Luca; García de Abajo, F. Javier; McGrouther, Damien; Barwick, B.; Carbone, F.

    2016-10-01

    Capturing and controlling plasmons at buried interfaces with nanometre and femtosecond resolution has yet to be achieved and is critical for next generation plasmonic devices. Here we use light to excite plasmonic interference patterns at a buried metal-dielectric interface in a nanostructured thin film. Plasmons are launched from a photoexcited array of nanocavities and their propagation is followed via photon-induced near-field electron microscopy (PINEM). The resulting movie directly captures the plasmon dynamics, allowing quantification of their group velocity at ~0.3 times the speed of light, consistent with our theoretical predictions. Furthermore, we show that the light polarization and nanocavity design can be tailored to shape transient plasmonic gratings at the nanoscale. This work, demonstrating dynamical imaging with PINEM, paves the way for the femtosecond and nanometre visualization and control of plasmonic fields in advanced heterostructures based on novel two-dimensional materials such as graphene, MoS2, and ultrathin metal films.

  17. Tunable long persistent luminescence in the second near-infrared window via crystal field control.

    PubMed

    Nie, Jianmin; Li, Yang; Liu, Shanshan; Chen, Qiuqun; Xu, Qi; Qiu, Jianrong

    2017-09-29

    Construction of an active composite as a biomarker with deeper tissue penetration and higher signal-to-noise ratio (SNR) is of great importance for the application in bioimaging. Here, we report a strategy for tuning the emission bandwidth and intensity via crystal field control in long persistent phosphors (LPPs). Ni 2+ -doped Zn 1+y Sn y Ga 2-x-2y O 4 phosphors, with a tunable emission band peaking from 1270 to 1430 nm in the second near-infrared (NIR) window, have been successfully prepared. Such featured materials have the advantages of low absorption and scattering as well as more efficient tissue penetration. The emission spectra can be controlled by tailoring the local crystal field around the activator precisely via substitution of Zn and Sn for Ga. Moreover, with high resolution and weak light disturbance, these developed multi-band afterglow phosphors exhibit great application potential in advanced optical imaging.

  18. Magnetic field shimming of a permanent magnet using a combination of pieces of permanent magnets and a single-channel shim coil for skeletal age assessment of children

    NASA Astrophysics Data System (ADS)

    Terada, Y.; Kono, S.; Ishizawa, K.; Inamura, S.; Uchiumi, T.; Tamada, D.; Kose, K.

    2013-05-01

    We adopted a combination of pieces of permanent magnets and a single-channel (SC) shim coil to shim the magnetic field in a magnetic resonance imaging system dedicated for skeletal age assessment of children. The target magnet was a 0.3-T open and compact permanent magnet tailored to the hand imaging of young children. The homogeneity of the magnetic field was first improved by shimming using pieces of permanent magnets. The residual local inhomogeneity was then compensated for by shimming using the SC shim coil. The effectiveness of the shimming was measured by imaging the left hands of human subjects and evaluating the image quality. The magnetic resonance images for the child subject clearly visualized anatomical structures of all bones necessary for skeletal age assessment, demonstrating the usefulness of combined shimming.

  19. Genome Editing Redefines Precision Medicine in the Cardiovascular Field

    PubMed Central

    Lahm, Harald; Dreßen, Martina; Lange, Rüdiger; Wu, Sean M.; Krane, Markus

    2018-01-01

    Genome editing is a powerful tool to study the function of specific genes and proteins important for development or disease. Recent technologies, especially CRISPR/Cas9 which is characterized by convenient handling and high precision, revolutionized the field of genome editing. Such tools have enormous potential for basic science as well as for regenerative medicine. Nevertheless, there are still several hurdles that have to be overcome, but patient-tailored therapies, termed precision medicine, seem to be within reach. In this review, we focus on the achievements and limitations of genome editing in the cardiovascular field. We explore different areas of cardiac research and highlight the most important developments: (1) the potential of genome editing in human pluripotent stem cells in basic research for disease modelling, drug screening, or reprogramming approaches and (2) the potential and remaining challenges of genome editing for regenerative therapies. Finally, we discuss social and ethical implications of these new technologies. PMID:29731778

  20. Biological Activation of Inert Ceramics: Recent Advances Using Tailored Self-Assembled Monolayers on Implant Ceramic Surfaces

    PubMed Central

    Böke, Frederik; Schickle, Karolina; Fischer, Horst

    2014-01-01

    High-strength ceramics as materials for medical implants have a long, research-intensive history. Yet, especially on applications where the ceramic components are in direct contact with the surrounding tissue, an unresolved issue is its inherent property of biological inertness. To combat this, several strategies have been investigated over the last couple of years. One promising approach investigates the technique of Self-Assembled Monolayers (SAM) and subsequent chemical functionalization to create a biologically active tissue-facing surface layer. Implementation of this would have a beneficial impact on several fields in modern implant medicine such as hip and knee arthroplasty, dental applications and related fields. This review aims to give a summarizing overview of the latest advances in this recently emerging field, along with thorough introductions of the underlying mechanism of SAMs and surface cell attachment mechanics on the cell side. PMID:28788687

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