USDA-ARS?s Scientific Manuscript database
Fluorescence and Raman inner filter effects (IFE) cause spectral distortion and nonlinearity between spectral signal intensity with increasing analyte concentration. Convenient and effective correction of fluorescence IFE has been an active research goal for decades. Presented herein is the finding ...
Spectroscopic investigation of inner filter effect by magnolol solutions
NASA Astrophysics Data System (ADS)
Li, Hongmei; YuzhuHu
2007-12-01
Spectroscopy is useful tool for aggregation studies on fluorephores. One of the major problems with this technique is that the inner filter effect becomes unavoidable since the samples are used at high concentration. In this work, our investigation on magnolol spectroscopic properties shows that the inner filter effect (IFE) of fluorescence plays a critical role in the spectra of magnolol. The strong dependence of the fluorescence parameters on the concentration accounts for the apparent experimental evidence of magnolol aggregation at high concentrations. There are some questions despite the aggregation model based on fluorescent aggregates seems to describe the behavior of the system. The mathematical correction on the emission intensities shows the linear fluorescence-concentration relationship. Furthermore, we propose a mathematic model of excitation spectrum based on the primary IFE (absorption of light of excitation wavelength), which provide a correct explanation of the unusual spectral shift and spectral narrowing in the excitation spectra of magnolol at high concentrations. The shapes of spectra are completely independent on magnolol aggregation and are due only to experimental artifacts, i.e. IFE.
NASA Astrophysics Data System (ADS)
Ding, Longhua; Yang, Hongmei; Ge, Shenguang; Yu, Jinghua
2018-03-01
A simple and effective fluorescent assay for the determination of vitamin B12 was developed. In this study, carbon dots (CDs) were prepared by one-pot hydrothermal method and directly used as a fluorophore in the inner filter effect (IFE). Both of the maximum absorption peak of vitamin B12 and excitation maxima of CDs are located at 360 nm, hence, the excited light of CDs can be absorbed by vitamin B12, resulting in the fluorescence reduction of CDs. And the fluorescence intensity of CDs decreases with the increasing concentration of vitamin B12. This IFE-based sensing strategy shows a good linear relationship between the normalized fluorescence intensity and the concentration of vitamin B12 ranging from 0 to 60 μM, with a limit of detection (LOD) of 0.1 μM at a signal-to-noise ratio of 3. Furthermore, this proposed approach was successfully applied to vitamin B12 sensing in injections. This IFE sensing platform based on various fluorescent nanomaterials has a high promise for the detection of other biomolecules due to its inherent convenience.
Liu, Yanyan; Li, Hongchang; Guo, Bin; Wei, Lijuan; Chen, Bo; Zhang, Youyu
2017-05-15
Herein we report a novel switch-off fluorescent probe for highly selective determination of uric acid (UA) based on the inner filter effect (IFE), by using poly-(vinylpyrrolidone)-protected gold nanoparticles (PVP-AuNPs) and chondroitin sulfate-stabilized gold nanoclusters (CS-AuNCs) as the IFE absorber/fluorophore pair. In this IFE-based fluorometric assay, the newly designed CS-AuNCs were explored as an original fluorophore and the hydrogen peroxide (H 2 O 2 ) -driven formed PVP-AuNPs can be a powerful absorber to influence the excitation of the fluorophore, due to the complementary overlap between the absorption band of PVP-AuNPs and the emission band of CS-AuNCs. Under the optimized conditions, the extent of the signal quenching depends linearly on the H 2 O 2 concentration in the range of 1-100μM (R 2 =0.995) with a detection limit down to 0.3μM. Based on the H 2 O 2 -dependent fluorescence IFE principle, we further developed a new assay strategy to enable selective sensing of UA by using a specific uricase-catalyzed UA oxidation as the in situ H 2 O 2 generator. The proposed uricase-linked IFE-based assay exhibited excellent analytical performance for measuring UA over the concentration ranging from 5 to 100μM (R 2 =0.991), and can be successfully applied to detection of UA as low as 1.7μM (3σ) in diluted human serum samples. Copyright © 2017 Elsevier B.V. All rights reserved.
A generalized model on the effects of nanoparticles on fluorophore fluorescence in solution
USDA-ARS?s Scientific Manuscript database
Nanoparticles (NP) can modify fluorophore fluorescence in solution through multiple pathways that include fluorescence inner filter effect (IFE), dynamic and static quenching, surface enhancement, and fluorophore quantum yield variation associated with structural and conformational modifications ind...
Lu, Shuaimin; Li, Guoliang; Lv, Zhengxian; Qiu, Nannan; Kong, Weiheng; Gong, Peiwei; Chen, Guang; Xia, Lian; Guo, Xiaoxi; You, Jinmao; Wu, Yongning
2016-11-15
Early detection and diagnosis have great practical significances for the effective prevention and treatment of cancer. In this study, we developed a novel, facile and ultra-sensitive fluorescence assay for the determination of tumor invasive biomarker β-glucuronidase (GLU) based on the inner-filter effect (IFE). The nitrogen-doped carbon quantum dots (N-CQDs) with green photoluminescence were employed as the fluorophore in IFE, and 4-nitrophenyl-β-D-glucuronide (PNPG) was used to act as GLU substrate, and GLU catalytic product (p-nitrophenol (PNP)) was capable of acting as the robust absorber in IFE to turn off the fluorescence of N-CQDs due to the complementary overlap between the absorption of PNP and the excitation of N-CQDs. Thus, signal of GLU activity could be recorded by the fluorescence intensity of N-CQDs. Unlike other fluorescence sensing mechanism such as fluorescence resonance energy transfer (FRET) or photoinduced electron transfer (PET), IFE has no requirement for electron or energy transfer process or any chemical modification of fluorophore, which makes our assay more flexible and simple. The proposed method exhibited a good linear relationship from 1UL(-1) to 60UL(-1) (R(2)=0.9967) with a low detection limit of 0.3UL(-1). This method was also successfully applied to the analysis of serum samples and the inhibitor screening from natural product. The developed sensor platform was proven to be reliable, facile, sensitive, and selective, making it promising as a candidate for GLU activity detection in clinic tumor diagnose and anti-tumor drug screening. Copyright © 2016 Elsevier B.V. All rights reserved.
NASA Astrophysics Data System (ADS)
Liu, Haijian; Li, Ming; Jiang, Linye; Shen, Feng; Hu, Yufeng; Ren, Xueqin
2017-02-01
Arginine plays an important role in many biological functions, whose detection is very significant. Herein, a sensitive, simple and cost-effective fluorescent method for the detection of arginine has been developed based on the inner filter effect (IFE) of citrate-stabilized gold nanoparticles (AuNPs) on the fluorescence of thioglycolic acid-capped CdTe quantum dots (QDs). When citrate-stabilized AuNPs were mixed with thioglycolic acid-capped CdTe QDs, the fluorescence of CdTe QDs was significantly quenched by AuNPs via the IFE. With the presence of arginine, arginine could induce the aggregation and corresponding absorption spectra change of AuNPs, which then IFE-decreased fluorescence could gradually recover with increasing amounts of arginine, achieving fluorescence ;turn on; sensing for arginine. The detection mechanism is clearly illustrated and various experimental conditions were also optimized. Under the optimum conditions, a decent linear relationship was obtained in the range from 16 to 121 μg L- 1 and the limit of detection was 5.6 μg L- 1. And satisfactory results were achieved in arginine analysis using arginine injection, compound amino acid injection, even blood plasma as samples. Therefore, the present assay showed various merits, such as simplicity, low cost, high sensitivity and selectivity, making it promising for sensing arginine in biological samples.
Lu, Hongzhi; Quan, Shuai; Xu, Shoufang
2017-11-08
In this work, we developed a simple and sensitive ratiometric fluorescent assay for sensing trinitrotoluene (TNT) based on the inner filter effect (IFE) between gold nanoparticles (AuNPs) and ratiometric fluorescent nanoparticles (RFNs), which was designed by hybridizing green emissive carbon dots (CDs) and red emissive quantum dots (QDs) into a silica sphere as a fluorophore pair. AuNPs in their dispersion state can be a powerful absorber to quench CDs, while the aggregated AuNPs can quench QDs in the IFE-based fluorescent assays as a result of complementary overlap between the absorption spectrum of AuNPs and emission spectrum of RFNs. As a result of the fact that TNT can induce the aggregation of AuNPs, with the addition of TNT, the fluorescent of QDs can be quenched, while the fluorescent of CDs would be recovered. Then, ratiometric fluorescent detection of TNT is feasible. The present IFE-based ratiometric fluorescent sensor can detect TNT ranging from 0.1 to 270 nM, with a detection limit of 0.029 nM. In addition, the developed method was successfully applied to investigate TNT in water and soil samples with satisfactory recoveries ranging from 95 to 103%, with precision below 4.5%. The simple sensing approach proposed here could improve the sensitivity of colorimetric analysis by changing the ultraviolet analysis to ratiometric fluorescent analysis and promote the development of a dual-mode detection system.
Kong, Weiheng; Wu, Di; Xia, Lian; Chen, Xuefeng; Li, Guoliang; Qiu, Nannan; Chen, Guang; Sun, Zhiwei; You, Jinmao; Wu, Yongning
2017-06-22
Recently, α-glucosidase inhibitor has been widely used in clinic for diabetic therapy. In the present study, a facile and sensitive fluorescent assay based on enzyme activated inner filter effect (IFE) on nitrogen-doped carbon dots (CDs) was first developed for the detection of α-glucosidase. The N-doped CDs with green emission were prepared by a one-step hydrothermal synthesis and gave the fluorescence quantum yield of 30%, which were used as the signal output. Through α-glucosidase catalysis, 4-nitrophenol was released from 4-nitrophenyl-α-d-glucopyranoside (NGP). Interestingly, the absorption of 4-nitrophenol and the excitation of CDs were completely overlapping. Due to its great molar absorptivity, 4-nitrophenol was capable of acting as a powerful absorber to affect the fluorescent signal of CDs (i.e. IFE). By converting the absorption signals into fluorescence signals, the facile fluorescence assay strategy could be realized for α-glucosidase activity sensing, which effectively avoided the complex modification of the surface of CDs or construction of the nanoprobes. The established IFE-based sensing platform offered a low detection limit of 0.01 U/mL (S/N = 3). This proposed sensing approach has also been expanded to the inhibitor screening and showed excellent applicability. As a typical α-glucosidase inhibitor, acarbose was investigated with a low detection limit of 10 -8 M. This developed method enjoyed many merits including simplicity, lost cost, high sensitivity, good reproducibility and excellent selectivity, which also provided a new insight on the application of CDs to develop the facile and sensitive biosensor. Copyright © 2017 Elsevier B.V. All rights reserved.
NASA Astrophysics Data System (ADS)
Dong, Liang; Hou, Changjun; Yang, Mei; Fa, Huanbao; Wu, Huixiang; Shen, Caihong; Huo, Danqun
2016-06-01
Cyanazine residue poses a great threat to human health and its derivatives would remain in soils, natural waters, and other environmental domains for a long time. Herein, a simple, rapid, and ultra-sensitive analytical method for the determination of cyanazine (CZ) based on inner filter effect (IFE) of Au nanoparticles (AuNPs) on the fluorescence of CdTe quantum dots (QDs) is first described in this study. With the presence of citrate-stabilized AuNPs, the fluorescence of GSH-capped CdTe QDs was remarkably quenched by AuNPs via IFE. The fluorescence of the AuNP-CdTe QD system was recovered upon addition of CZ. CZ can adsorb on to the surface of AuNPs due to its cyano group that has good affinity with gold, which could induce the aggregation of AuNPs accompanying color change from red to blue. Thus, the IFE of AuNPs on CdTe QDs was weakened, and the fluorescence intensity of CdTe QDs was recovered accordingly. A good linear correlation for detection of CZ was exhibited from 0.05 to 9 μM, and the detection limit reached 0.1568 μM, which was much lower than the safety limit required by the USA, the UK, and China. In order to probe into the selectivity of AuNPs towards CZ over other pesticides, various frequently used pesticides were mixed with AuNPs. AuNP composite solution shows good selectivity towards CZ among other pesticides. This method was successfully carried out for the assessment of CZ in real samples with satisfactory results, which revealed many advantages such as high sensitivity, low cost, and non-time-consuming compared with traditional methods.
Yan, Xu; Li, Hongxia; Han, Xiaosong; Su, Xingguang
2015-12-15
In this work, we develop a novel and sensitive sensor for the detection of organophosphorus pesticides based on the inner-filter effect (IFE) between gold nanoparticles (AuNPs) and ratiometric fluorescent quantum dots (RF-QDs). The RF-QDs has been designed by hybridizing two differently colored CdTe QDs, in which the red emissive QDs entrapped in the silica sphere acting as the reference signal, and the green emissive QDs covalently attached on the silica surface serving as the response signal.The fluorescence of RF-QDs could be quenched by AuNPs based on IFE. Protamine could effectively turn on the fluorescence due to the electrostatic attraction between protamine and AuNPs. Trypsin can easily hydrolyze protamine, leading to the quench of the fluorescence. Then, the fluorescence could be recovered again by the addition of parathion-methyl (PM) which could inhibit the activity of trypsin. By measuring the fluorescence of RF-QDs, the inhibition efficiency of PM to trypsin activity was evaluated. Under the optimized conditions, the inhibition efficiency was proportional to the logarithm of PM concentration in the range of 0.04-400 ng mL(-1), with a detection limit of 0.018 ng mL(-1). Furthermore, the simple and convenient method had been used for PM detection in environmental and agricultural samples with satisfactory results. Copyright © 2015 Elsevier B.V. All rights reserved.
Zhao, Jianru; Pan, Xiaohua; Sun, Xiaobo; Pan, Wei; Yu, Guifeng; Wang, Jinping
2018-06-01
In this work, carbon dots (CDs) with a high quantum yield (22.3%) were easily prepared by hydrothermal pyrolysis of acid fuchsin 6B and hydrogen peroxide at 180°C for 10 h. The resultant CDs possess a narrow size distribution in the range of 2.6 to 3.2 nm and emit blue fluorescence. Interestingly, the absorption band of metronidazole (MTZ) centered at 318 nm can complementary overlap with the excitation band of the as-prepared CDs centered at 320 nm, resulting in an inner filter effect (IFE) in high efficiency. In fact, the fluorescence quenching of the CDs depends on the concentration of MTZ. Therefore, a simple method for the detection of MTZ can be established using the CDs-based sensor via the IFE. The linear range of the proposed method was 0-10 μg mL -1 with the limit of detection as low as 0.257 μg mL -1 . This CDs-based sensor had been applied for the detection of MTZ in honey and MTZ tablets with the recoveries in the range of 98.0% to 105.1% and 95.7% to 106.5%, respectively. Therefore, the as-prepared CDs have a potential to be developed as a MTZ sensor with high selectivity, sensitivity and accuracy. Copyright © 2018 John Wiley & Sons, Ltd.
NASA Astrophysics Data System (ADS)
Udhayakumar, M.; Prabakaran, K.; Rajesh, K. B.; Jaroszewicz, Z.; Belafhal, Abdelmajid; Velauthapillai, Dhayalan
2018-06-01
Based on vector diffraction theory and inverse Faraday effect (IFE), the light induced magnetization distribution of a tightly focused azimuthally polarized doughnut Gaussian beam superimposed with a helical phase and modulated by an optimized multi belt complex phase filter (MBCPF) is analysed numerically. It is noted that by adjusting the radii of different rings of the complex phase filter, one can achieve many novel magnetization focal distribution such as sub wavelength scale (0.29λ) and super long (52.2λ) longitudinal magnetic probe suitable for all optical magnetic recording and the formation of multiple magnetization chain with four, six and eight sub-wavelength spherical magnetization spots suitable for multiple trapping of magnetic particles are achieved.
Plasmon mediated inverse Faraday effect in a graphene-dielectric-metal structure.
Bychkov, Igor V; Kuzmin, Dmitry A; Tolkachev, Valentine A; Plaksin, Pavel S; Shavrov, Vladimir G
2018-01-01
This Letter shows the features of inverse Faraday effect (IFE) in a graphene-dielectric-metal (GDM) structure. The constants of propagation and attenuation of the surface plasmon-polariton modes are calculated. The effective magnetic field induced by surface plasmon modes in the dielectric due to the IFE is estimated to reach above 1 tesla. The possibility to control the distribution of the magnetic field by chemical potential of graphene is shown. The concept of strain-driven control of the IFE in the structure has been proposed and investigated.
Diode-pumped solid state lasers (DPSSLs) for Inertial Fusion Energy (IFE)
DOE Office of Scientific and Technical Information (OSTI.GOV)
Krupke, W.F.
The status of diode-pumped, transverse-gas-flow cooled, Yb-S-FAP slab lasers is reviewed. Recently acquired experimental performance data are combined with a cost/performance IFE driver design code to define a cost-effective development path for IFE DPSSL drivers. Specific design parameters are described for the Mercury 100J/10 Hz, 1 kW system (first in the development scenario).
Investigating the Density of Isolated Field Elliptical Galaxies
NASA Astrophysics Data System (ADS)
Ulgen, E. Kaan
2016-02-01
In this thesis, 215.590 elliptical galaxies with M(r) ≤ -21 in the CFHTLS-W1 field which is covering 72 sq. deg on the sky are examined . Criterion given by Smith et al. (2004) has been used to determine isolated elliptical galaxies. 118 isolated elliptical galaxies have been determined in total. By using g, r and i photometric bands, the true-colour images of candidates are produced and visually inspected. In order to have a clean list of IfEs some candidates are excluded from the final sample after visual inspection. The final sample consists of 60 IfEs which corresponds to the 0.027 per cent of the whole sample. In other words, IfE density in the W1 is 0.8 IfE / sq.deg. Since the formation of the ellipticals in the isolated regions is not known clearly, it is crucial to determine IfEs and compare their photometric and morphological properties to the normal or cluster ellipticals. When the (g-i) distributions of three different elliptical galaxy class are compared, it is found that they have almost the same colours. When the redshift distributions of the galaxies are considered, it can be seen that IfEs formed later than the cluster and normal ellipticals. The average redshift of IfEs is determined as zphot=0.284, while for normal and cluster ellipticals, it is, respectively, 0.410 and 0.732. In addition, when the effective radii of the three elliptical systems are considered, it is found that the IfEs are bigger than the other two elliptical classes.
Tang, Yanli; Liu, Yue; Cao, Ali
2013-01-15
A new strategy was developed and applied in monitoring pH response and enzyme activity based on fluorescence emission red shift (FERS) of the conjugated polymer PPP-OR10 induced by the inner filter effect (IFE) of nitrobenzene derivatives. Neutral poly(p-phenylenes) functionalized with oligo(oxyethylene) side chains (PPP-OR10) was designed and synthesized by the Suzuki cross-coupling reaction. Nitrobenzene derivatives display different light absorption activities in the acidic or basic form due to adopting different electron-transition types. When environmental pH is higher than their pK(a) values, nitrobenzene derivatives exhibit strong absorbance around 400 nm, which is close to the maximal emission of polymer PPP-OR10. As a result, the maximal emission wavelength of PPP-OR10/nitrobenzene derivatives red shifts with the pH value increasing. Apparently, the IFE plays a very important role in this case. A new method has been designed that takes advantage of this pH-sensitive platform to sensor α-chymotrypsin (ChT) based on the IFE of p-nitroaniline, since the absorption spectrum of p-nitroaniline, the ChT-hydrolyzed product of N-benzoyl-L-tyrosine-p-nitroaniline (BTNA), overlaps with the emission spectrum of PPP-OR10. In addition, the present approach can detect α-chymotrypsin with a detection limit of 0.1 μM, which is lower than that of the corresponding absorption spectroscopy method. Furthermore, the pH response and enzyme detections can be carried out in 10% serum, which makes this new FERS-based strategy promising in applications in more complex conditions and a broader field.
Gerst, Michael D; Cox, Michael E; Locke, Kim A; Laser, Mark; Kapuscinski, Anne R
2015-01-20
Predominant forms of food and energy systems pose multiple challenges to the environment as current configurations tend to be structured around centralized one-way through-put of materials and energy. In addition, these configurations can introduce vulnerability to input material price and supply shocks as well as contribute to localized food insecurity and lost opportunities for less environmentally harmful forms of local economic development. One proposed form of system transformation involves locally integrating “unclosed” material and energy loops from food and energy systems. Such systems, which have been termed integrated food-energy systems (IFES), have existed in diverse niche forms but have not been systematically studied with respect to technological, governance, and environmental differences. As a first step in this process, we have constructed a taxonomy of IFES archetypes by using exploratory data analysis on a collection of IFES cases. We find that IFES may be classified hierarchically first by their primary purpose—food or energy production—and subsequently by degree and direction of vertical supply chain coordination. We then use this taxonomy to delineate potential governance challenges and pose a research agenda aimed at understanding what role IFES may play in food and energy system transformation and ultimately what policies may encourage IFES adoption.
Nanodust released in interplanetary collisions
NASA Astrophysics Data System (ADS)
Lai, H. R.; Russell, C. T.
2018-07-01
The lifecycle of near-Earth objects (NEOs) involves a collisional cascade that produces ever smaller debris ending with nanoscale particles which are removed from the solar system by radiation pressure and electromagnetic effects. It has been proposed that the nanodust clouds released in collisions perturb the background interplanetary magnetic field and create the interplanetary field enhancements (IFEs). Assuming that this IFE formation scenario is actually operating, we calculate the interplanetary collision rate, estimate the total debris mass carried by nanodust, and compare the collision rate with the IFE rate. We find that to release the same amount of nanodust, the collision rate is comparable to the observed IFE rate. Besides quantitatively testing the association between the collisions evolving large objects and giant solar wind structures, such a study can be extended to ranges of smaller scales and to investigate the source of moderate and small solar wind perturbations.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Klein-Szanto, A.J.P.; Major, S.K.; Slaga, T.J.
1980-05-01
12-O-Tetradecanoylphorbol-13-acetate (TPA) and mezerein (MZ) are diterpene esters of similar structure and approximately equipotent on a molar basis as far as their hyperplasiogenic, inflammatogenic, and induction of ornithine decarboxylase activity effects in mouse skin are concerned. On the other hand, TPA is much more effective than MZ as a tumor promoter. The percentage of dark basal keratinocytes was determined in the interfollicular epidermis (IFE) of mice topically treated with 1, 2, or 4 ..mu..g of either TPA or MZ in a single application and studied at 12, 24, 48, 96, and 144 h thereafter. The results showed that TPA inducedmore » 2 to 3 times more dark cells than MZ in the IFE as well as in the infundibular portion of the hair follicle. The latter epithelium presented a larger number of dark keratinocytes than the IFE in all experimental and control situations, and the differences between the effects of TPA and MZ were even greater in the infundibular epidermis than in the IFE. TPA induced an increase of 5 to 11 times over the control number of dark cells (approx. 2% in IFE), reaching maximum values of 21% in the basal layer 24 h after topical application of 4 ..mu..g of TPA. MZ only produced a 3- to 6-fold increment. The labeling indices of the basal layer and of the dark basal cells were markedly and similarly increased with both compounds. The different dark-cell inducing characteristics seem to be the only detectable difference in early effects produced by TPA and MZ and would point to the importance of the production of the dedifferentiated dark cells during early stages of tumor promotion.« less
An audit of immunofixation requesting practices at a South African referral laboratory
Rampursat, Yashna
2014-01-01
Background It is common practice in most chemical pathology laboratories for reflective immunofixation electrophoresis (IFE) to occur following the detection or suspicion of a paraprotein on serum protein electrophoresis (SPEP). The chemical pathology laboratory at Inkosi Albert Luthuli Central Hospital (IALCH) in Durban, South Africa, is currently the only non-private laboratory in the KwaZulu Natal province that performs SPEP analysis, with current practice requiring that the clinician request IFE following suggestion by the laboratory after a suspicious SPEP result. Objectives To review the current process for IFE at IALCH in the context of reflective testing and to examine the use of the alpha-2-globulin/alpha-1-globulin ratio as a predictor of a positive IFE result. Methods Data for 1260 consecutive SPEP tests performed at the IALCH National Health Laboratory Service were collected between February and July 2011. SPEP and IFE were performed with a Sebia Hydrasys automated electrophoresis system. The alpha-2-globulin/alpha-1-globulin ratio was calculated using density of corresponding fractions on SPEP. Results Analysis revealed that of the 1260 SPEPs performed during the analysis period, 304 IFEs were suggested by the reviewing pathologist. A total of 45 (15%) of the suggested IFEs were subsequently requested by the attending clinicians. Almost half (46.5%) (n = 20) of the suggested IFEs that were performed revealed the presence of a paraprotein. There was no statistically-significant difference between the alpha-2-globulin/alpha-1-globulin ratio for patients with positive or negative IFEs (p-value = 0.2). Conclusions This study reveals the need for reflective addition of IFE testing by the laboratory following suspicious findings on SPEP. PMID:29043173
Intelligent Front-end Electronics for Silicon photodetectors (IFES)
NASA Astrophysics Data System (ADS)
Sauerzopf, Clemens; Gruber, Lukas; Suzuki, Ken; Zmeskal, Johann; Widmann, Eberhard
2016-05-01
While high channel density can be easily achieved for big experiments using custom made microchips, providing something similar for small and medium size experiments imposes a challenge. Within this work we describe a novel and cost effective solution to operate silicon photodetectors such as silicon photo multipliers (SiPM). The IFES modules provide the bias voltage for the detectors, a leading edge discriminator featuring time over threshold and a differential amplifier, all on one printed circuit board. We demonstrate under realistic conditions that the module is usable for high resolution timing measurements exploiting both charge and time information. Furthermore we show that the modules can be easily used in larger detector arrays. All in all this confirms that the IFES modules are a viable option for a broad range of experiments if cost-effectiveness and small form factor are required.
IFE Chamber Technology - Status and Future Challenges
DOE Office of Scientific and Technical Information (OSTI.GOV)
Meier, W.R.; Raffray, A.R.; Abdel-Khalik, S.I.
2003-07-15
Significant progress has been made on addressing critical issues for inertial fusion energy (IFE) chambers for heavy-ion, laser and Z-pinch drivers. A variety of chamber concepts are being investigated including drywall (currently favored for laser IFE), wetted-wall (applicable to both laser and ion drivers), and thick-liquid-wall (favored by heavy ion and z-pinch drivers). Recent progress and remaining challenges in developing IFE chambers are reviewed.
Christian, Michael R; Pallasch, Erin M; Wahl, Michael; Mycyk, Mark B
2013-09-01
Intravenous fat emulsion (IFE) therapy is a novel treatment that has been used to reverse the acute toxicity of some xenobiotics with varied success. We sought to determine how US Poison Control Centers (PCCs) have incorporated IFE as a treatment strategy for poisoning. A closed-format multiple-choice survey instrument was developed, piloted, revised, and then sent electronically to every medical director of an accredited US PCC in March 2011. Addresses were obtained from the American Association of Poison Control Centers listserv, and participation was voluntary and remained anonymous. Data were analyzed using descriptive statistics. The majority of PCC medical directors completed the survey (45 out of 57; 79 %). Of the 45 respondents, all felt that IFE therapy played a role in the acute overdose setting. Most PCCs (30 out of 45; 67 %) have a protocol for IFE therapy. In a scenario with "cardiac arrest" due to a single xenobiotic, directors stated that their center would "always" or "often" recommend IFE after overdose of bupivacaine (43 out of 45; 96 %), verapamil (36 out of 45; 80 %), amitriptyline (31 out of 45; 69 %), or an unknown xenobiotic (12 out of 45; 27 %). In a scenario with "shock" due to a single xenobiotic, directors stated that their PCC would "always" or "often" recommend IFE after overdose of bupivacaine (40 out of 45; 89 %), verapamil (28 out of 45; 62 %), amitriptyline (25 out of 45; 56 %), or an unknown xenobiotic (8 out of 45; 18 %). IFE therapy is being recommended by US PCCs; protocols and dosing regimens are nearly uniform. Most directors feel that IFE is safe but are more likely to recommend IFE in patients with cardiac arrest than in patients with severe hemodynamic compromise.
Federal Register 2010, 2011, 2012, 2013, 2014
2010-06-01
... DEPARTMENT OF STATE [Public Notice 7032] Culturally Significant Objects Imported for Exhibition Determinations: ``Dynasty and Divinity: Ife Art in Ancient Nigeria'' SUMMARY: Notice is hereby given of the... included in the exhibition ``Dynasty and Divinity: Ife Art in Ancient Nigeria,'' imported from abroad for...
Li, C; Wen, Y B; Li, H; Su, W; Li, J; Cai, J F; Chen, L M; Li, X M; Li, X W
2017-08-08
Objective: To investigate the value of serum free light chain (FLC) in differential diagnosis of monoclonal gammopathy of renal significance (MGRS). Methods: Forty-nine hospitalized patients who underwent renal biopsy in Peking Union Medical College Hospital between January 2013 and December 2015 were included. Monoclonal gammopathy was detected by serum protein electrophoresis (SPE), serum immunofixation electrophoresis (IFE), urine IFE and serum FLC. All patients were classified as MGRS ( n =32) and monoclonal gammopathy of undetermined significance (MGUS) ( n =17). Results: Renal lesions in MGRS subgroup included light chain amyloidosis ( n =24, 75.0%), light chain deposition disease ( n =7, 21.9%), and fibrillary glomerulopathy ( n =1, 3.1%). Renal diseases in MGUS subgroup included membranous nephropathy ( n =10), focal segmental glomerulosclerosi (FSGS) ( n =3), diabetic glomerulopathy ( n =1), Henoch-Schonlein purpura nephritis ( n =1), anti-GBM disease concurrent with membranous nephropathy ( n =1) and glomerulomegaly ( n =1). Positive number of SPE, serum IFE, urine IFE and abnormal number of serum FLC ratio in MGRS subgroup were 12, 16, 23 and 30, respectively. Positive number of SPE, serum IFE, urine IFE and abnormal number of serum FLC ratio in MGUS subgroup were 11, 17, 6 and 3, respectively. MGRS and MGUS subgroups differed significantly in positive rate of serum IFE ( P <0.001), as well as positive rate of urine IFE ( P =0.02) and abnormal rate of serum FLC ratio ( P <0.001). The sensitivity, specificity, total consistent rate of serum FLC ratio for diagnosis of MGRS were 93.8%, 82.4%, and 89.8% respectively. The sensitivity for diagnosing MGRS could be increased to 100% by combining serum FLC ratio and urine IFE. Conclusions: The significance of monoclonal gammopathy in patients with renal disease should be evaluated by renal pathology.On the premise of excluding lymphoplasmacytic malignancy, serum FLC ratio had promising diagnostic value for MGRS, which was helpful for differential diagnosis of patients who had contraindication to renal biopsy.
NASA Astrophysics Data System (ADS)
Nakai, S.; Yamanaka, M.; Kitagawa, Y.; Fujita, K.; Heya, M.; Mima, K.; Izawa, Y.; Nakatsuka, M.; Murakami, M.; Ueda, K.; Sasaki, T.; Mori, Y.; Kanabe, T.; Hiruma, T.; Kan, H.; Kawashima, T.
2006-06-01
The typical specifications of the laser driver for a commercial IFE power plant are (1) total energy (MJ/pulse) with a tailored 20-40 ns pulse, (2) repetition operation (˜ 10 Hz), (3) efficiency (˜ 10%) with enough robustness and low cost. The key elements of the DPSSL driver technology are under development with HALNA. The HALNA 10 (High Average-power Laser for Nuclear-fusion Application) demonstrated 10 J × 10 Hz operation and the HALNA 100 (100 J × 10 Hz) is now under construction. By using the high average power and high intensity lasers, new industrial applications are being proceeded. The collaborative process for the development of high power laser with industry and for the industrial applications is effective and essential in the development of the laser driver for IFE power plant.
The width-tapered double cantilever beam for interlaminar fracture testing
NASA Technical Reports Server (NTRS)
Bascom, W. D.; Jensen, R. M.; Bullman, G. W.; Hunston, D. L.
1984-01-01
The width-tapered double-cantilever-beam (WTDCB) specimen configuration used to determine the Mode-I interlaminar fracture energy (IFE) of composites has special advantages for routine development work and for quality-assurance purposes. These advantages come primarily from the simplicity of testing and the fact that the specimen is designed for constant change in compliance with crack length, so that the computation of Mode-I IFE is independent of crack length. In this paper, a simplified technique for fabrication and testing WTDCB specimens is described. Also presented are the effects of fiber orientation and specimen dimensions, a comparison of data obtained using the WTDCB specimens and other specimen geometries, and comparison of data obtained at different laboratories. It is concluded that the WTDCB gives interlaminar Mode-I IFE essentially equal to other type specimens, and that it can be used for rapid screening in resin-development work and for quality assurance of composite materials.
Integrated Food-Energy Systems: Challenges and Opportunities
NASA Astrophysics Data System (ADS)
Gerst, M.; Cox, M. E.; Locke, K. A.; Laser, M.; Raker, M.; Gooch, C.; Kapuscinski, A. R.
2015-12-01
Predominant forms of food and energy systems pose multiple challenges to the environment as current configurations tend to be structured around centralized one-way through-put of materials and energy. One proposed form of system transformation involves locally integrating "unclosed" material and energy loops from food and energy systems. Such systems, which have been termed integrated food-energy systems (IFES), have existed in diverse niche forms but have not been systematically studied with respect to technological, governance, and environmental differences. This is likely because IFES can have widely different configurations, from co-located renewable energy production on cropland to agroforestry. As a first step in creating a synthesis of IFES, our research team constructed a taxonomy using exploratory data analysis of diverse IFES cases (Gerst et al., 2015, ES&T 49:734-741). It was found that IFES may be categorized by type of primary product produced (plant- or animal-based food or energy) and the degree and direction of vertical supply chain coordination. To further explore these implications, we have begun a study of a highly-coordinated, animal-driven IFES: dairy farms with biogas production from anaerobic digestion of manure. The objectives of the research are to understand the barriers to adoption and the potential benefits to the farms financial resilience and to the environment. To address these objectives, we are interviewing 50 farms across New York and Vermont, collecting information on farmer decision-making and farm operation. These results will be used to calibrate biophysical and economic models of the farm in order understand the future conditions under which adoption of an IFES is beneficial.
Harmon, Thomas M.; Fisher, Kevin A.; McGlynn, Margaret G.; Stover, John; Warren, Mitchell J.; Teng, Yu; Näveke, Arne
2016-01-01
Background The Investment Framework Enhanced (IFE) proposed in 2013 by the Joint United Nations Programme on HIV/AIDS (UNAIDS) explored how maximizing existing interventions and adding emerging prevention options, including a vaccine, could further reduce new HIV infections and AIDS-related deaths in low- and middle-income countries (LMICs). This article describes additional modeling which looks more closely at the potential health impact and cost-effectiveness of AIDS vaccination in LMICs as part of UNAIDS IFE. Methods An epidemiological model was used to explore the potential impact of AIDS vaccination in LMICs in combination with other interventions through 2070. Assumptions were based on perspectives from research, vaccination and public health experts, as well as observations from other HIV/AIDS interventions and vaccination programs. Sensitivity analyses varied vaccine efficacy, duration of protection, coverage, and cost. Results If UNAIDS IFE goals were fully achieved, new annual HIV infections in LMICs would decline from 2.0 million in 2014 to 550,000 in 2070. A 70% efficacious vaccine introduced in 2027 with three doses, strong uptake and five years of protection would reduce annual new infections by 44% over the first decade, by 65% the first 25 years and by 78% to 122,000 in 2070. Vaccine impact would be much greater if the assumptions in UNAIDS IFE were not fully achieved. An AIDS vaccine would be cost-effective within a wide range of scenarios. Interpretation Even a modestly effective vaccine could contribute strongly to a sustainable response to HIV/AIDS and be cost-effective, even with optimistic assumptions about other interventions. Higher efficacy would provide even greater impact and cost-effectiveness, and would support broader access. Vaccine efficacy and cost per regimen are critical in achieving cost-effectiveness, with cost per regimen being particularly critical in low-income countries and at lower efficacy levels. PMID:26731116
Hypersensitivity to total parenteral nutrition fat-emulsion component in an egg-allergic child.
Lunn, Michael; Fausnight, Tracy
2011-10-01
Immunoglobulin E (IgE)-mediated food allergies affect 6% to 8% of children in the United States with symptoms ranging from localized hives to life-threatening anaphylaxis. Intravenous fat emulsions (IFEs) are a vital component of total parental nutrition, because they provide essential fatty acids. IFE is a sterile fat emulsion that contains egg-yolk phospholipids. Although egg allergy is listed as a contraindication, adverse reactions are uncommon. We report here the case of a hypersensitivity to IFE in a 2-year-old patient with previously undocumented egg allergy. Our patient was placed on total parental nutrition and a 20% IFE postoperatively and developed diffuse pruritus 14 days after initiation of therapy. She showed transient improvement with intravenous antihistamine, but her symptoms did not resolve until the IFE was stopped. On the basis of clinical history, including aversion to egg, we performed skin-prick testing, the results of which were positive for egg white allergy. Serum testing confirmed allergy to both egg yolk and egg white. To our knowledge, this is the first reported case of a pediatric patient with a history suggestive of egg allergy, positive skin-prick and serum testing to egg, and reaction to IFE infusion. Although ingestion of egg lecithin in cooked food is generally tolerated by egg-allergic people, administration of intravenous egg-containing lipid emulsions may cause significant adverse reactions.
Burnett, Jonathan L; Miley, Harry S; Milbrath, Brian D
2016-03-01
In 2014 the Preparatory Commission for the Comprehensive Nuclear-Test-Ban Treaty Organization (CTBTO) undertook an Integrated Field Exercise (IFE14) in Jordan. The exercise consisted of a simulated 0.5-2 kT underground nuclear explosion triggering an On-site Inspection (OSI) to search for evidence of a Treaty violation. This research paper evaluates two of the OSI techniques used during the IFE14, laboratory-based gamma-spectrometry of soil samples and in-situ gamma-spectrometry, both of which were implemented to search for 17 OSI relevant particulate radionuclides indicative of nuclear explosions. The detection sensitivity is evaluated using real IFE and model data. It indicates that higher sensitivity laboratory measurements are the optimum technique during the IFE and within the Treaty/Protocol-specified OSI timeframes. Copyright © 2016 Elsevier Ltd. All rights reserved.
Ibhafidon, Lawrence I; Obaseki, Daniel O; Erhabor, Gregory E; Akor, Alexander A; Irabor, Iziegbe; Obioh, Ib
2014-01-01
Particulate air pollution is associated with increased incidence of respiratory symptoms and decreased pulmonary, function but the relative impact of pollution from different domestic energy sources is not well-known or studied. The study was aimed at assessing the association between particulate concentrations, respiratory symptoms and lung function. It was a cross-sectional study comprised of randomly selected residents of three communities. These communities were selected according to the predominant type of fuel used for household cooking which were: firewood, kerosene and liquefied petroleum gas (LPG). Assessment of the indoor PM10 levels was done by filtration using the Gent stacked filter unit sampler for collection of atmospheric aerosol in two size fractions (PM2.5 and PM10). The Medical Research Council (MRC) questionnaire was administered followed by spirometry test. The mean PM10 concentration in participants using LPG, kerosene and firewood was 80.8 ± 9.52 μg/m(3), 236.9 ± 26.5 μg/m(3) and 269 ±93.7 μg/m(3), respectively. The mean age and height-adjusted percent predicted forced expiratory volumes in 1 s (FEV1) for men were 127 ± 7, 109 ± 40 and 91 ± 20 and for women were 129 ± 13, 115 ± 14, 100 ± 14 in users of LPG, kerosene and firewood, respectively. A similar trend was found in the forced vital capacity (FVCs). Users of firewood had significantly lower FEV1 and FVC compared with LPG users (P < 0.05). The participants using firewood had the highest prevalence of pulmonary and non-pulmonary symptoms (57.1%), whereas subjects using LPG had the lowest (23.8%). There are high levels of particulate matter pollutions with respiratory effects in residential indoor environments in Ile-Ife, Nigeria.
NASA Astrophysics Data System (ADS)
Sussman, A. J.; Macleod, G.; Labak, P.; Malich, G.; Rowlands, A. P.; Craven, J.; Sweeney, J. J.; Chiappini, M.; Tuckwell, G.; Sankey, P.
2015-12-01
The Integrated Field Exercise of 2014 (IFE14) was an event held in the Hashemite Kingdom of Jordan (with concurrent activities in Austria) that tested the operational and technical capabilities of an on-site inspection (OSI) within the CTBT verification regime. During an OSI, up to 40 international inspectors will search an area for evidence of a nuclear explosion. Over 250 experts from ~50 countries were involved in IFE14 (the largest simulation of a real OSI to date) and worked from a number of different directions, such as the Exercise Management and Control Teams (which executed the scenario in which the exercise was played) and those participants performing as members of the Inspection Team (IT). One of the main objectives of IFE14 was to test and integrate Treaty allowed inspection techniques, including a number of geophysical and remote sensing methods. In order to develop a scenario in which the simulated exercise could be carried out, suites of physical features in the IFE14 inspection area were designed and engineered by the Scenario Task Force (STF) that the IT could detect by applying the geophysical and remote sensing inspection technologies, in addition to other techniques allowed by the CTBT. For example, in preparation for IFE14, the STF modeled a seismic triggering event that was provided to the IT to prompt them to detect and localize aftershocks in the vicinity of a possible explosion. Similarly, the STF planted shallow targets such as borehole casings and pipes for detection using other geophysical methods. In addition, airborne technologies, which included multi-spectral imaging, were deployed such that the IT could identify freshly exposed surfaces, imported materials, and other areas that had been subject to modification. This presentation will introduce the CTBT and OSI, explain the IFE14 in terms of the goals specific to geophysical and remote sensing methods, and show how both the preparation for and execution of IFE14 meet those goals.
NASA Astrophysics Data System (ADS)
Labak, Peter; Sussman, Aviva; Rowlands, Aled; Chiappini, Massimo; Malich, Gregor; MacLeod, Gordon; Sankey, Peter; Sweeney, Jerry; Tuckwell, George
2016-04-01
The Integrated Field Exercise of 2014 (IFE14) was a field event held in the Hashemite Kingdom of Jordan (with concurrent activities in Austria) that tested the operational and technical capabilities of a Comprehensive Test Ban Treaty's (CTBT) on-site inspection (OSI). During an OSI, up to 40 inspectors search a 1000km2 inspection area for evidence of a nuclear explosion. Over 250 experts from ~50 countries were involved in IFE14 (the largest simulation of an OSI to date) and worked from a number of different directions, such as the Exercise Management and Control Teams to execute the scenario in which the exercise was played, to those participants performing as members of the Inspection Team (IT). One of the main objectives of IFE14 was to test Treaty allowed inspection techniques, including a number of geophysical and remote sensing methods. In order to develop a scenario in which the simulated exercise could be carried out, a number of physical features in the IFE14 inspection area were designed and engineered by the Scenario Task Force Group (STF) that the IT could detect by applying the geophysical and remote sensing inspection technologies, as well as other techniques allowed by the CTBT. For example, in preparation for IFE14, the STF modeled a seismic triggering event that was provided to the IT to prompt them to detect and localize aftershocks in the vicinity of a possible explosion. Similarly, the STF planted shallow targets such as borehole casings and pipes for detection by other geophysical methods. In addition, airborne technologies, which included multi-spectral imaging, were deployed such that the IT could identify freshly exposed surfaces, imported materials and other areas that had been subject to modification. This presentation will introduce the CTBT and OSI, explain the IFE14 in terms of goals specific to geophysical and remote sensing methods, and show how both the preparation for and execution of IFE14 meet those goals.
The role of inertial fusion energy in the energy marketplace of the 21st century and beyond
NASA Astrophysics Data System (ADS)
John Perkins, L.
The viability of inertial fusion in the 21st century and beyond will be determined by its ultimate cost, complexity, and development path relative to other competing, long term, primary energy sources. We examine this potential marketplace in terms of projections for population growth, energy demands, competing fuel sources and environmental constraints (CO 2), and show that the two competitors for inertial fusion energy (IFE) in the medium and long term are methane gas hydrates and advanced, breeder fission; both have potential fuel reserves that will last for thousands of years. Relative to other classes of fusion concepts, we argue that the single largest advantage of the inertial route is the perception by future customers that the IFE fusion power core could achieve credible capacity factors, a result of its relative simplicity, the decoupling of the driver and reactor chamber, and the potential to employ thick liquid walls. In particular, we show that the size, cost and complexity of the IFE reactor chamber is little different to a fission reactor vessel of the same thermal power. Therefore, relative to fission, because of IFE's tangible advantages in safety, environment, waste disposal, fuel supply and proliferation, our research in advanced targets and innovative drivers can lead to a certain, reduced-size driver at which future utility executives will be indifferent to the choice of an advanced fission plant or an advanced IFE power plant; from this point on, we have a competitive commercial product. Finally, given that the major potential customer for energy in the next century is the present developing world, we put the case for future IFE "reservations" which could be viable propositions providing sufficient reliability and redundancy can be realized for each modular reactor unit.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Burnett, Jonathan L.; Miley, Harry S.; Milbrath, Brian D.
In 2014 the Comprehensive Nuclear-Test-Ban Treaty Organization (CTBTO) undertook the Integrated Field Exercise (IFE) in Jordan. The exercise consisted of a simulated 0.5 – 2 kT underground explosion triggering an On-site Inspection (OSI) to search for evidence of a Treaty violation. This research evaluates two of the OSI techniques, including laboratory-based gamma-spectrometry of soil samples and in situ gamma-spectrometry for 17 particulate radionuclides indicative of nuclear weapon tests. The detection sensitivity is evaluated using real IFE and model data. It indicates that higher sensitivity laboratory measurements are the optimum technique during the IFE and OSI timeframes.
NASA Astrophysics Data System (ADS)
Cao, Huijun; Cao, Yong; Chu, Yuchuan; He, Xiaoming; Lin, Tao
2018-06-01
Surface evolution is an unavoidable issue in engineering plasma applications. In this article an iterative method for modeling plasma-surface interactions with moving interface is proposed and validated. In this method, the plasma dynamics is simulated by an immersed finite element particle-in-cell (IFE-PIC) method, and the surface evolution is modeled by the Huygens wavelet method which is coupled with the iteration of the IFE-PIC method. Numerical experiments, including prototypical engineering applications, such as the erosion of Hall thruster channel wall, are presented to demonstrate features of this Huygens IFE-PIC method for simulating the dynamic plasma-surface interactions.
78 FR 23691 - Airworthiness Directives; the Boeing Company
Federal Register 2010, 2011, 2012, 2013, 2014
2013-04-22
... off electrical power to the in-flight entertainment (IFE) systems and other non-essential electrical...., Washington, DC 20590. FOR FURTHER INFORMATION CONTACT: Ray Mei, Aerospace Engineer, Systems and Equipment... circuit breaker, relays, and wiring to allow the flightcrew to turn off electrical power to the IFE...
Childhood Facial Recognition Predicts Adolescent Symptom Severity in Autism Spectrum Disorder.
Eussen, Mart L J M; Louwerse, Anneke; Herba, Catherine M; Van Gool, Arthur R; Verheij, Fop; Verhulst, Frank C; Greaves-Lord, Kirstin
2015-06-01
Limited accuracy and speed in facial recognition (FR) and in the identification of facial emotions (IFE) have been shown in autism spectrum disorders (ASD). This study aimed at evaluating the predictive value of atypicalities in FR and IFE for future symptom severity in children with ASD. Therefore we performed a seven-year follow-up study in 87 children with ASD. FR and IFE were assessed in childhood (T1: age 6-12) using the Amsterdam Neuropsychological Tasks (ANT). Symptom severity was assessed using the Autism Diagnostic Observation Schedule (ADOS) in childhood and again seven years later during adolescence (T2: age 12-19). Multiple regression analyses were performed to investigate whether FR and IFE in childhood predicted ASD symptom severity in adolescence, while controlling for ASD symptom severity in childhood. We found that more accurate FR significantly predicted lower adolescent ASD symptom severity scores (ΔR(2) = .09), even when controlling for childhood ASD symptom severity. IFE was not a significant predictor of ASD symptom severity in adolescence. From these results it can be concluded, that in children with ASD the accuracy of FR in childhood is a relevant predictor of ASD symptom severity in adolescence. Test results on FR in children with ASD may have prognostic value regarding later symptom severity. © 2015 International Society for Autism Research, Wiley Periodicals, Inc.
The Seismic Aftershock Monitoring System (SAMS) for OSI - Experiences from IFE14
NASA Astrophysics Data System (ADS)
Gestermann, Nicolai; Sick, Benjamin; Häge, Martin; Blake, Thomas; Labak, Peter; Joswig, Manfred
2016-04-01
An on-site inspection (OSI) is the third of four elements of the verification regime of the Comprehensive Nuclear-Test-Ban Treaty (CTBT). The sole purpose of an OSI is to confirm whether a nuclear weapon test explosion or any other nuclear explosion has been carried out in violation of the treaty and to gather any facts which might assist in identifying any possible violator. It thus constitutes the final verification measure under the CTBT if all other available measures are not able to confirm the nature of a suspicious event. The Provisional Technical Secretariat (PTS) carried out the Integrated Field Exercise 2014 (IFE14) in the Dead Sea Area of Jordan from 3 November to 9. December 2014. It was a fictitious OSI whose aim was to test the inspection capabilities in an integrated manner. The technologies allowed during an OSI are listed in the Treaty. The aim of the Seismic Aftershock Monitoring System (SAMS) is to detect and localize aftershocks of low magnitudes of the triggering event or collapses of underground cavities. The locations of these events are expected in the vicinity of a possible previous explosion and help to narrow down the search area within an inspection area (IA) of an OSI. The success of SAMS depends on the main elements, hardware, software, deployment strategy, the search logic and not least the effective use of personnel. All elements of SAMS were tested and improved during the Built-Up Exercises (BUE) which took place in Austria and Hungary. IFE14 provided more realistic climatic and hazardous terrain conditions with limited resources. Significant variations in topography of the IA of IFE14 in the mountainous Dead Sea Area of Jordan led to considerable challenges which were not expected from experiences encountered during BUE. The SAMS uses mini arrays with an aperture of about 100 meters and with a total of 4 elements. The station network deployed during IFE14 and results of the data analysis will be presented. Possible aftershocks of the triggering event are expected in a very low magnitude range. Therefore the detection threshold of the network is one of the key parameters of SAMS and crucial for the success of the monitoring. One of the objectives was to record magnitude values down to -2.0 ML. The threshold values have been compared with historical seismicity in the region and those monitored during IFE14. Results of the threshold detection estimation and experiences of the exercise will be presented.
Hsieh, Kao-Hsian; Soong, Wen-Jue; Jeng, Mei-Jy; Lee, Yu-Sheng; Tsao, Pei-Chen; Chou, Ya-Ling
2018-02-01
Esophageal stenosis (ES) is characterized by dysphagia, failure to thrive, and long-term disability. It requires repeated management because it is refractory. Traditionally, these procedures are performed under general anesthesia with airway intubation. This study investigated the safety and efficacy of the management of interventional flexible endoscopy (IFE) performed with a novel noninvasive ventilation (NIV) support. Use of a short-length flexible endoscope with NIV of pharyngeal oxygen, nose closure, and abdominal compression during IFE was investigated. Medical charts of patients aged ≤10 years with a diagnosis of ES in our hospital between 1990 and 2014 were reviewed and analyzed. The outcome measurement included the number of IFE with balloon dilatation (BD), laser therapy (LT), stent placement, procedural complications, and the success rate. Ten patients were enrolled. The most common etiologies were esophageal atresia with/without tracheoesophageal fistula (n = 6), followed by caustic injury (n = 2), and unknown etiology (n = 2). Nine patients who were considered successfully managed received an average of 2.8 BD sessions and 1.6 LT sessions. The complication rate of IFE in this study was 1.08% (1/93). One esophageal perforation developed after BD (1/63) and none after LT (0/30). In this study, IFE with this NIV support is a safe, feasible and valuable modality which could rapidly examine and manage ES. Copyright © 2017. Published by Elsevier B.V.
Management of Primary Dysmenorrhea by School Adolescents in ILE-IFE, Nigeria
ERIC Educational Resources Information Center
Ogunfowokan, Adesola A.; Babatunde, Oluwayemisi A.
2010-01-01
Dysmenorrhea is a problem that girls and women face and often manage themselves with or without support from health professionals. A cross-sectional, descriptive study was conducted among adolescents with dysmenorrhea (N = 150) in Ile-Ife, Nigeria. The aims of the study were to determine their knowledge of menstruation and primary dysmenorrhea,…
Parental Socio-Economic Status as Correlate of Child Labour in Ile-Ife, Nigeria
ERIC Educational Resources Information Center
Elegbeleye, O. S.; Olasupo, M. O.
2012-01-01
This study investigated the relationship between parental socio-economic status and child labour practices in Ile-Ife, Nigeria. The study employed survey method to gather data from 200 parents which constituted the study population. Pearson Product Moment Correlation and t-test statistics were used for the data analyses. The outcome of the study…
Scientific and technological advancements in inertial fusion energy
Hinkel, D. E.
2013-09-26
Scientific advancements in inertial fusion energy (IFE) were reported on at the IAEA Fusion Energy Conference, October 2012. Results presented transect the different ways to assemble the fuel, different scenarios for igniting the fuel, and progress in IFE technologies. The achievements of the National Ignition Campaign within the USA, using the National Ignition Facility (NIF) to indirectly drive laser fusion, have found beneficial the achievements in other IFE arenas such as directly driven laser fusion and target fabrication. Moreover, the successes at NIF have pay-off to alternative scenarios such as fast ignition, shock ignition, and heavy-ion fusion as well asmore » to directly driven laser fusion. As a result, this synergy is summarized here, and future scientific studies are detailed.« less
Ibhafidon, Lawrence I.; Obaseki, Daniel O.; Erhabor, Gregory E.; Akor, Alexander A.; Irabor, Iziegbe; Obioh, IB
2014-01-01
Introduction: Particulate air pollution is associated with increased incidence of respiratory symptoms and decreased pulmonary, function but the relative impact of pollution from different domestic energy sources is not well-known or studied. Aim: The study was aimed at assessing the association between particulate concentrations, respiratory symptoms and lung function. Materials and Methods: It was a cross-sectional study comprised of randomly selected residents of three communities. These communities were selected according to the predominant type of fuel used for household cooking which were: firewood, kerosene and liquefied petroleum gas (LPG). Assessment of the indoor PM10 levels was done by filtration using the Gent stacked filter unit sampler for collection of atmospheric aerosol in two size fractions (PM2.5 and PM10). The Medical Research Council (MRC) questionnaire was administered followed by spirometry test. Results: The mean PM10 concentration in participants using LPG, kerosene and firewood was 80.8 ± 9.52 μg/m3, 236.9 ± 26.5 μg/m3 and 269 ±93.7 μg/m3, respectively. The mean age and height-adjusted percent predicted forced expiratory volumes in 1 s (FEV1) for men were 127 ± 7, 109 ± 40 and 91 ± 20 and for women were 129 ± 13, 115 ± 14, 100 ± 14 in users of LPG, kerosene and firewood, respectively. A similar trend was found in the forced vital capacity (FVCs). Users of firewood had significantly lower FEV1 and FVC compared with LPG users (P < 0.05). The participants using firewood had the highest prevalence of pulmonary and non-pulmonary symptoms (57.1%), whereas subjects using LPG had the lowest (23.8%). Conclusion: There are high levels of particulate matter pollutions with respiratory effects in residential indoor environments in Ile-Ife, Nigeria PMID:24970970
ERIC Educational Resources Information Center
Alaba, Sofowora Olaniyi; Adekomi, Bimbo
2012-01-01
The study assessed the impact of a World Bank Assisted Project "STEP-B" on teaching and learning of Science, Technology and Mathematics Education (STM) in Nigeria. It also described the contribution of Obafemi Awolowo University, Ile-Ife to the improvement of STM through research development, utilization of ICT, human resources and…
DOE Office of Scientific and Technical Information (OSTI.GOV)
Meier, W.R.; Bieri, R.L.; Monsler, M.J.
1992-03-01
The primary objective of the of the IFE Reactor Design Studies was to provide the Office of Fusion Energy with an evaluation of the potential of inertial fusion for electric power production. The term reactor studies is somewhat of a misnomer since these studies included the conceptual design and analysis of all aspects of the IFE power plants: the chambers, heat transport and power conversion systems, other balance of plant facilities, target systems (including the target production, injection, and tracking systems), and the two drivers. The scope of the IFE Reactor Design Studies was quite ambitious. The majority of ourmore » effort was spent on the conceptual design of two IFE electric power plants, one using an induction linac heavy ion beam (HIB) driver and the other using a Krypton Fluoride (KrF) laser driver. After the two point designs were developed, they were assessed in terms of their (1) environmental and safety aspects; (2) reliability, availability, and maintainability; (3) technical issues and technology development requirements; and (4) economics. Finally, we compared the design features and the results of the assessments for the two designs.« less
Zhang, Yuhua; Fang, Xian; Zhao, Hong; Li, Zengxi
2018-05-01
A highly sensitive and selective detection of hexavalent chromium (Cr(VI)) and ascorbic acid (AA) was proposed using nitrogen-doped carbon dots (N-CDs). In the absence of AA, the quantitative detection of Cr(VI) was realized through Cr(VI) acting as a quencher to quench the fluorescence of N-CDs by inner filter effect (IFE) and static quenching effect. Under the optimal conditions, the linear range for Cr(VI) detection was from 0.01 to 250μM with a detection limit of 5nM (S/N = 3). In the presence of AA, the fluorescence intensity could be rapidly enhanced compared with the fluorescence of N-CDs/Cr(VI) system since Cr(VI) can be reduced into trivalent chromium (Cr(III)) by AA. And a wide linear range for AA detection was obtained from 1 to 750μM. The detection limit was 0.3μM (S/N = 3). More importantly, this method can be successfully applied to the detection of Cr(VI) in real water samples, and AA in vitamins C tablets and human serum sample. Copyright © 2018 Elsevier B.V. All rights reserved.
Bhatt, Shreya; Bhatt, Madhuri; Kumar, Anshu; Vyas, Gaurav; Gajaria, Tejal; Paul, Parimal
2018-07-01
We report a one pot green strategy for the synthesis of carbon dots using tulsi leaves and their potential application in sensing of Cr(VI) selectively. The detection mechanism is based on the phenomenon called inner filter effect (IFE) and a good linear static quenching was observed in the range of 1.6 μM to 50 μM with a detection limit of 4.5 ppb. The reversible switching in fluorescence has been tested and a good recovery in fluorescence was observed up to three consecutive cycles upon addition of ascorbic acid as reducing agent. Also the low toxicity, high fluorescence and photostabilty of the CDs make them excellent imaging and patterning agent. The acid and alkali resistant property of these CDs makes it suitable for real sample analysis. The fluorescent CDs were applied for successful detection of Cr(VI) in water with spike-recoveries ranging from 93 to 99%. Copyright © 2018 Elsevier B.V. All rights reserved.
NASA Astrophysics Data System (ADS)
Panigrahi, Suraj Kumar; Mishra, Ashok Kumar
2017-09-01
A combination of broad-band UV radiation (UV A and UV B; 250-400 nm) and a stretched exponential function (StrEF) has been utilised in efforts towards convenient and sensitive detection of fluorescent dissolved organic matter (FDOM). This approach enables accessing the gross fluorescence spectral signature of both protein-like and humic-like components in a single measurement. Commercial FDOM components are excited with the broad-band UV excitation; the variation of spectral profile as a function of varying component ratio is analysed. The underlying fluorescence dynamics and non-linear quenching of amino acid moieties are studied with the StrEF (exp(-V[Q] β )). The complex quenching pattern reflects the inner filter effect (IFE) as well as inter-component interactions. The inter-component interactions are essentially captured through the ‘sphere of action’ and ‘dark complex’ models. The broad-band UV excitation ascertains increased excitation energy, resulting in increased population density in the excited state and thereby resulting in enhanced sensitivity.
Tarai, Madhumita; Mishra, Ashok Kumar
2016-10-12
The phenomenon of concentration dependent red shift, often observed in synchronous fluorescence spectra (SFS) of monofluorophoric as well as multifluorophoric systems at high chromophore concentrations, is known to have good analytical advantages. This was previously understood in terms of large inner filter effect (IFE) through the introduction of a derived absorption spectral profile that closely corresponds to the SFS profile. Using representative monofluorophoric and multifluorophoric systems, it is now explained how the SF spectral maximum changes with concentration of the fluorophore. For dilute solutions of monofluorophores the maximum is unchanged as expected. It is shown here that the onset of red shift of SFS maximum of both the mono as well as the multifluorophoric systems must occur at the derived absorption spectral parameter value of 0.32 that corresponds to the absorbance value of 0.87. This value is unique irrespective of the nature of the fluorophore under study. For monofluorophoric systems, the wavelength of derived absorption spectral maximum and the wavelength of synchronous fluorescence spectral maximum closely correspond with each other in the entire concentration range. In contrast, for multifluorophoric systems like diesel and aqueous humic acid, large deviations were noted that could be explained as to be due to the presence of non-fluorescing chromophores in the system. This work bridges the entire fluorophore concentration range over which the red shift of SFS maximum sets in; and in the process it establishes the importance of the derived absorption spectral parameter in understanding the phenomenon of concentration dependent red shift of SFS maximum. Copyright © 2016 Elsevier B.V. All rights reserved.
ERIC Educational Resources Information Center
Egbedokun, A. O.; Oyewusi, L. M.
2014-01-01
This paper focuses the potentials of information and communication technologies (ICT) on three main areas as related to students learning (possession, perception and problems). It investigated students' possession, perception and problems (as envisaged or experienced) by students of Obafemi Awolowo University, Ile-Ife on the use of ICT facilities.…
New structure of high-pressure body-centered orthorhombic Fe 2SiO 4
Yamanaka, Takamitsu; Kyono, Atsushi; Nakamoto, Yuki; ...
2015-08-01
Here, a structural change in Fe 2SiO 4 spinel and the structure of a new high pressure phase are determined by Rietveld 26 profile fitting of x-ray diffraction data up to 64 GPa at ambient temperature. The compression curve of the spinel is discontinuous at approximately 20 GPa. Fe Kβ x-ray emission measurements at high pressure show that the transition from a high spin (HS) to an intermediate spin (IS) state begins at 17 GPa in the spinel phase. The IS electronic state is gradually enhanced with pressure, which results in an isostructural phase transition. A transition from the cubic spinel structure to a body centered orthorhombic phase (I-Fe 2SiO 4) with space group Imma and Z=4 was observed at approximately 34 GPa. The structure of I-Fe 2SiO 4 has two crystallographically distinct FeO 6 octahedra, which are arranged in layers parallel to (101) and (011) and are very similar to the layers of FeO 6 octahedra that constitute the spinel structure. Silicon also exists in six-fold coordination in I-Fe 2SiO 4. The transformation to the new high-pressure phase is reversible under decompression at ambient temperature. A Martensitic transformation of each slab of the spinel structure with translation vector [more » $$\\vec{1/8}$$ $$\\vec{1/8}$$ $$\\vec{1/8}$$] generates the I-Fe 2SiO 4 structure. Laser heating of I-Fe 2SiO 4 at 1500 K results in a decomposition of the material to rhombohedral FeO and SiO 2 stishovite.« less
EPA'S LIFE CYCLE METHODOLOGY: GUIDELINES FOR USE IN DEVELOPMENT OF PACKAGING
Approaches to reducing environmental effects of products and processes have moved steadily upstream over the years from end-of-pipe controls to source reduction and recycling of hazardous waste, and more recently, toward multimedia pollution prevention. ife Cycle Assessment (LCA)...
ERIC Educational Resources Information Center
Adeyemi, B. A.
2014-01-01
The study examined the level of ICT competence among Social Studies undergraduates of Obafemi Awolowo University, Ile-Ife, Nigeria. It also investigated the influence of motivation variables as well as the influence of self concept on the acquisition of ICT competence. This was with a view to improving ICT competence in higher institutions of…
Traumatic spinal cord injuries in Ile-Ife, Nigeria, and its environs.
Olasode, Babatunde J; Komolafe, I E; Komolafe, M; Olasode, Olayinka A
2006-07-01
In Ile-Ife, Nigeria, traumatic brain injuries are largely due to traffic accidents caused mainly by the bad maintenance of the roads and unsafe driving. Young men in the productive stage of their lives are those most affected. The resultant disabilities include quadriplegia (in more than half the patients) and paraplegia. The cost of treating and providing adequate facilities for these patients imposes a heavy economic burden upon developing countries.
The IfE Global Gravity Field Model Recovered from GOCE Orbit and Gradiometer Data
NASA Astrophysics Data System (ADS)
Wu, Hu; Muiller, Jurgen; Brieden, Phillip
2015-03-01
An independent global gravity field model is computed from the GOCE orbit and gradiometer data using our own IfE software. We analysed the same data period that were considered for the first released GOCE models. The Acceleration Approach is applied to process the orbit data. The gravity gradients are processed in the framework of the remove-restore technique by which the low-frequency noise of the original gradients are removed. For the combined solution, the normal equations are summed by the Variance Component Estimation Approach. The result in terms of accumulated geoid height error calculated from the coefficient difference w.r.t. EGM2008 is about 11 cm at D/O 200, which corresponds to the accuracy level of the first released TIM and DIR solutions. This indicates that our IfE model has a comparable performance as the other official GOCE models.
Oke, Olaide Olutoyin; Onayemi, Olaniyi; Olasode, Olayinka Abimbola; Omisore, Akinlolu Gabriel; Oninla, Olumayowa Abimbola
2014-01-01
Fungal infections of the skin and nails are common global problems with attendant morbidity among affected individuals. Children are mostly affected due to predisposing factors such as overcrowding and low socioeconomic factors. The aim of this study was to determine the prevalence and the clinical patterns of superficial fungal infections among primary school children in Ile-Ife. A multistage sampling was conducted to select eight hundred pupils from ten primary schools in Ile-Ife. Data on epidemiological characteristics and clinical history was collected using a semistructured questionnaire and skin scrapings were done. The prevalence of superficial fungal infections among the 800 respondents was 35.0%. Male pupils constituted 51.0% of respondents while the females were 49.0%. The mean age for all the respondents was 9.42 ± 2.00. Tinea capitis was the commonest infection with a prevalence of 26.9% and tinea unguium, tinea corporis, and tinea faciei had a prevalence of 0.8%, 0.6%, and 0.5%, respectively. Tinea manuum had the least prevalence of 0.1%. Pityriasis versicolor had a prevalence of 4.4%. Microsporum audouinii was the leading organism isolated. The study shows that the prevalence of superficial fungal infection (SFI) among primary school children in Ile-Ife is high with tinea capitis as the commonest SFI. PMID:25574161
Analysis of IFE, EFE and QSPM matrix on business development strategy
NASA Astrophysics Data System (ADS)
Zulkarnain, A.; Wahyuningtias, D.; Putranto, T. S.
2018-03-01
IFE matrix, EFE matrix, and QSPM matrix are business strategy tools that can be used to identify the threat, opportunity, weakness, strength as internal, external business factors. The goal of Danti’s Deli Bakery is to provide pastry product and distribute to other food and beverage outlet all around Jakarta. Thus, Danti’s Deli Bakery requires development strategy in order to win the tight competition. Applied descriptive research and data collected from focus group discussion, questionnaire, interview, observation and literature review. The objectives of this paper are (1) to identify and evaluate internal and external factors, (2) to formulate alternative strategy toward business development program, and (3) to give effective recommendation. The result shows that Danti’s Deli Bakery should apply product differentiation strategy. Implementation of this study is providing the recommendation for pastry and bakery industry to establish a successful business.
Gwathmey, TanYa M; Willis, Monte S; Tatreau, Jason; Wang, Shaobin; McCudden, Christopher R
2015-03-01
Serum protein electrophoresis (SPE) and immunofixation is commonly used to screen for plasma cell dyscrasias. Interpretation of these tests is qualitative by nature and can yield trace, faint, or scarcely visible immunoglobulin bands (TFS), which can be difficult to classify. Whether these bands should be reported at all is challenging given their unknown clinical significance. In the present study, we retrospectively analyzed 14,036 physician-ordered protein SPE and immunofixation electrophoresis (IFE) tests on serum and urine specimens (from 4,091 patients) during the period of 2000-2010. We found that 17% of all IFE results evaluated for the presence of monoclonal gammopathies (2,389 out of 14,036) contained TFS bands, representing 4.2% (173 out of 4091) of all patients evaluated. Sixty of these patients (42%) had no previous history of gammopathy, and were clinically evaluated over a mean period of up to five years from the original diagnosis of plasma cell pathology. None of these patients had progressed to multiple myeloma, lymphoplasmacytic lymphoma, plasmacytoma, or leukemia. The remaining 82 patients (58%) had a previous history of gammopathy, but had not progressed to any symptomatic plasma cell dyscrasia. Evaluation of these patients was followed for a median period of 4.3 years, with a mean of 21.5 IFE tests per individual. These data suggest that for patients without a previous history of gammopathy, the presence of TFS bands on serum protein electrophoresis does not warrant frequent follow up investigation as commonly practiced. Routine follow up of patients with a prior history of gammopathy, conversely, are warranted and may contribute to overall survival with multiple treatment options now available. For those interpreting IFE results, it may be worth considering these data when composing comments regarding suggested repeat testing frequency by SPE/IFE or alternate test methods.
Gwathmey, TanYa M.; Willis, Monte S.; Tatreau, Jason; Wang, Shaobin; McCudden, Christopher R.
2015-01-01
Serum protein electrophoresis (SPE) and immunofixation is commonly used to screen for plasma cell dyscrasias. Interpretation of these tests is qualitative by nature and can yield trace, faint, or scarcely visible immunoglobulin bands (TFS), which can be difficult to classify. Whether these bands should be reported at all is challenging given their unknown clinical significance. In the present study, we retrospectively analyzed 14,036 physician-ordered protein SPE and immunofixation electrophoresis (IFE) tests on serum and urine specimens (from 4,091 patients) during the period of 2000-2010. We found that 17% of all IFE results evaluated for the presence of monoclonal gammopathies (2,389 out of 14,036) contained TFS bands, representing 4.2% (173 out of 4091) of all patients evaluated. Sixty of these patients (42%) had no previous history of gammopathy, and were clinically evaluated over a mean period of up to five years from the original diagnosis of plasma cell pathology. None of these patients had progressed to multiple myeloma, lymphoplasmacytic lymphoma, plasmacytoma, or leukemia. The remaining 82 patients (58%) had a previous history of gammopathy, but had not progressed to any symptomatic plasma cell dyscrasia. Evaluation of these patients was followed for a median period of 4.3 years, with a mean of 21.5 IFE tests per individual. These data suggest that for patients without a previous history of gammopathy, the presence of TFS bands on serum protein electrophoresis does not warrant frequent follow up investigation as commonly practiced. Routine follow up of patients with a prior history of gammopathy, conversely, are warranted and may contribute to overall survival with multiple treatment options now available. For those interpreting IFE results, it may be worth considering these data when composing comments regarding suggested repeat testing frequency by SPE/IFE or alternate test methods. PMID:27683487
1986-11-01
START THE RUN>>> USERNUIDNUPW. CHARGEGROUPNPID. SETJOB, DC= NO . COMMENT . GET CR ATTACH THE INPUT DATA TO GO TO VSOS. GET, INDATA=DATFILE/NA. IFE...NtPW. CHARGEGROUPNPID. SETTL, 200. SETJOB. DC= NO . COMMENT . RUN SAIL ON NOS TO GENERATE THE MAIN PROGRAM. PURGE, SAl LOUT/NA. PURGE, PROG-PROBLEMID...NOSPASS. CHARGEDFCDFCPR.F. SETJOB. DC= NO . COMMENT . GET OR ATTACH THE INPUT DATA To Go To VSOS. GET. INDATA=MYDATA/NA. IFE. .NOT.FILE(INDATA.AS) .DOATT
ERIC Educational Resources Information Center
Okoye, Nnamdi S.
2008-01-01
The study investigated the selective attentional effects of adjunct study questions inserted before or after the presentation of science flow diagrams. The basic design for the study was a post-test only control group design involving a total of 252 students randomly selected from six secondary schools in Ile-Ife, Oshun State Nigeria. These were…
Hemoglobin detection using carbon dots as a fluorescence probe.
Barati, Ali; Shamsipur, Mojtaba; Abdollahi, Hamid
2015-09-15
Herein, we have described the application of high fluorescent carbon dots (CDs) without any surface modification as a simple and fast responding fluorescence probe for sensitive and selective determination of hemoglobin (Hb) in the presence of H2O2. Although Hb itself was able to quench the fluorescence of CDs, based on the inner filter effect (IFE) of the protein that affects both excitation and emission spectra of CDs, the presence of H2O2 resulted in further improvement of the sensitivity of Hb detection. The assay is based on the reaction of Hb with H2O2 that generates reactive oxygen species including hydroxyl (OH•) and superoxide (O2(•-)) radicals under heme degradation and/or iron release from Hb and the subsequent reaction of hydroxyl radicals, as strong oxidizing agents, with CDs resulting in high fluorescence quenching. The proposed probe was used for determination of Hb in concentration range of 1-100 nM with a detection limit of 0.4 nM. The method was successfully applied to the determination of Hb in human blood samples. Copyright © 2015 Elsevier B.V. All rights reserved.
Ajao, K O; Ojofeitimi, E O; Adebayo, A A; Fatusi, A O; Afolabi, O T
2010-12-01
Fertility pattern and reproductive behaviours affect infant death in Nigeria. Household food insecurity and poor care practices also place children at risk of morbidity and mortality. The objectives of this study were to assess the influence of family size, household food security status, and child care practices on the nutritional status of under-five children in Ile-Ife, Nigeria. The study employed a descriptive cross-sectional design. A semi-structured questionnaire was used to collect data from 423 mothers of under-five children and their children in the households selected through multistage sampling methods. Food-insecure households were five times more likely than secure households to have wasted children (crude OR = 5.707, 95 percent CI = 1.31-24.85). Children with less educated mothers were significantly more likely to be stunted. The prevalence of food insecurity among households in Ile-Ife was high. Households with food insecurity and less educated mothers were more likely to have malnourished children.
McCudden, Christopher; Axel, Amy E; Slaets, Dominique; Dejoie, Thomas; Clemens, Pamela L; Frans, Sandy; Bald, Jaime; Plesner, Torben; Jacobs, Joannes F M; van de Donk, Niels W C J; Moreau, Philippe; Schecter, Jordan M; Ahmadi, Tahamtan; Sasser, A Kate
2016-06-01
Monoclonal antibodies are promising anti-myeloma treatments. As immunoglobulins, monoclonal antibodies have the potential to be identified by serum protein electrophoresis (SPE) and immunofixation electrophoresis (IFE). Therapeutic antibody interference with standard clinical SPE and IFE can confound the use of these tests for response assessment in clinical trials and disease monitoring. To discriminate between endogenous myeloma protein and daratumumab, a daratumumab-specific immunofixation electrophoresis reflex assay (DIRA) was developed using a mouse anti-daratumumab antibody. To evaluate whether anti-daratumumab bound to and shifted the migration pattern of daratumumab, it was spiked into daratumumab-containing serum and resolved by IFE/SPE. The presence (DIRA positive) or absence (DIRA negative) of residual M-protein in daratumumab-treated patient samples was evaluated using predetermined assessment criteria. DIRA was evaluated for specificity, limit of sensitivity, and reproducibility. In all of the tested samples, DIRA distinguished between daratumumab and residual M-protein in commercial serum samples spiked with daratumumab and in daratumumab-treated patient samples. The DIRA limit of sensitivity was 0.2 g/L daratumumab, using spiking experiments. Results from DIRA were reproducible over multiple days, operators, and assays. The anti-daratumumab antibody was highly specific for daratumumab and did not shift endogenous M-protein. As the treatment of myeloma evolves to incorporate novel monoclonal antibodies, additional solutions will be needed for clinical monitoring of patient responses to therapeutic regimens. In the interim, assays such as DIRA can inform clinical outcomes by distinguishing daratumumab from endogenous M-protein by IFE.
van de Glind, Gerline C; Rebel, Heggert G; Out-Luiting, Jacoba J; Zoutman, Wim; Tensen, Cornelis P; de Gruijl, Frank R
2016-12-27
Lgr6+ cells have been identified as a novel class of proliferating (Ki67+) stem cells in mouse epidermis. We investigated their response to UV exposure in Lgr6-EGFP-Ires-CreERT2/R26R-LacZ haired and hairless mice and whether they become initiating cells of UV- or chemically induced skin tumors. UV overexposure erased Lgr6+ cells (EGFP+) from the interfollicular epidermis (IFE), but - as after wounding - they apparently repopulated the IFE from the hair follicles. Under sub-sunburn chronic UV exposure, Lgr6+ cells and their progeny (LacZ+ after pulse of tamoxifen) diminished strongly in the IFE. Although the inter-tumoral IFE clearly showed Lgr6 progeny, none of the UV- or chemically induced tumors (n = 22 and 41, respectively) appeared to be clonal expansions of Lgr6+ stem cells; i.e. no Lgr6+ cells or progeny in the proliferating tumor bulk. In checking for promoter methylation we found it to occur stochastically for the EGFP-Cre cassette. Lgr6 mRNA measured by qPCR was found to be diminished in skin tumors (also in UV tumors from wt type mice). The ratio of Lgr6/Ki67 was significantly reduced, pointing at a loss of Lgr6+ cells from the proliferative pool. Our data show that Lgr6+ cells are not major tumor-initiating cells in skin carcinogenesis.
van de Glind, Gerline C.; Rebel, Heggert G.; Out-Luiting, Jacoba J.; Zoutman, Wim; Tensen, Cornelis P.; de Gruijl, Frank R.
2016-01-01
Lgr6+ cells have been identified as a novel class of proliferating (Ki67+) stem cells in mouse epidermis. We investigated their response to UV exposure in Lgr6-EGFP-Ires-CreERT2/R26R-LacZ haired and hairless mice and whether they become initiating cells of UV- or chemically induced skin tumors. UV overexposure erased Lgr6+ cells (EGFP+) from the interfollicular epidermis (IFE), but - as after wounding - they apparently repopulated the IFE from the hair follicles. Under sub-sunburn chronic UV exposure, Lgr6+ cells and their progeny (LacZ+ after pulse of tamoxifen) diminished strongly in the IFE. Although the inter-tumoral IFE clearly showed Lgr6 progeny, none of the UV- or chemically induced tumors (n = 22 and 41, respectively) appeared to be clonal expansions of Lgr6+ stem cells; i.e. no Lgr6+ cells or progeny in the proliferating tumor bulk. In checking for promoter methylation we found it to occur stochastically for the EGFP-Cre cassette. Lgr6 mRNA measured by qPCR was found to be diminished in skin tumors (also in UV tumors from wt type mice). The ratio of Lgr6/Ki67 was significantly reduced, pointing at a loss of Lgr6+ cells from the proliferative pool. Our data show that Lgr6+ cells are not major tumor-initiating cells in skin carcinogenesis. PMID:27880932
Optical Helicity-Manipulated Photocurrents and Photovoltages in Organic Solar Cells
Wei, Mengmeng; Hao, Xiaotao; Saxena, Avadh Behari; ...
2018-05-29
The performance of an organic functional device can be effectively improved through external field manipulation. In this study, we experimentally demonstrate the optical polarization manipulation of the photocurrent or photovoltage in organic solar cells. Through switching the incident light from a linearly polarized light to a circularly polarized one, we find a pronounced change in the photocurrent, which is not observable in normal inorganic cells. There are two competing hypotheses for the primary process underlying the circular polarization-dependent phenomena in organic materials, one involving the inverse Faraday effect (IFE) and the other a direct photon spin–electron spin interaction. By waymore » of ingenious device design and external magnetic field-induced stimuli, it is expected that the organic IFE can be a powerful experimental tool in revealing and elucidating excited-state processes occurring in organic spintronic and optoelectronic devices. Therefore, we believe that our results will potentially lead to the development of new multifunctional organic devices with integrated electronic, optical, and magnetic properties for energy conversion, optical communication, and sensing technologies.« less
Optical Helicity-Manipulated Photocurrents and Photovoltages in Organic Solar Cells
DOE Office of Scientific and Technical Information (OSTI.GOV)
Wei, Mengmeng; Hao, Xiaotao; Saxena, Avadh Behari
The performance of an organic functional device can be effectively improved through external field manipulation. In this study, we experimentally demonstrate the optical polarization manipulation of the photocurrent or photovoltage in organic solar cells. Through switching the incident light from a linearly polarized light to a circularly polarized one, we find a pronounced change in the photocurrent, which is not observable in normal inorganic cells. There are two competing hypotheses for the primary process underlying the circular polarization-dependent phenomena in organic materials, one involving the inverse Faraday effect (IFE) and the other a direct photon spin–electron spin interaction. By waymore » of ingenious device design and external magnetic field-induced stimuli, it is expected that the organic IFE can be a powerful experimental tool in revealing and elucidating excited-state processes occurring in organic spintronic and optoelectronic devices. Therefore, we believe that our results will potentially lead to the development of new multifunctional organic devices with integrated electronic, optical, and magnetic properties for energy conversion, optical communication, and sensing technologies.« less
Policy and experiment in mother tongue literacy in Nigeria
NASA Astrophysics Data System (ADS)
Akinnaso, F. Niyi
1993-07-01
The advocacy for initial mother tongue literacy in elementary schools and in adult education has been intensified within the past three decades, reflecting new attitudes to cultural diversity, especially to multilingual and multicultural education. This paper assesses the efforts made in one country, Nigeria, to achieve mother tongue literacy for its citizens, through a comparative analysis of the national policy on mother tongue literacy and the Ife experimental project, whose major purpose was to test the effectiveness of the use of the mother tongue as a medium of instruction throughout the six years of primary education. Although, like the Ife project, many experimental projects on mother tongue literacy in other countries are shown to have succeeded in realizing their objectives, the findings highlight the mediating effects of several non-linguistic variables. The findings indicate that its use as the medium of instruction in schools cannot compensate for the deficiencies in the educational system, particularly poor quality instructional facilities, or the social barriers in the wider society which prevent certain groups of minority children from learning well in school. The implications of the findings are discussed.
New structure of high-pressure body-centered orthorhombic Fe 2 SiO 4
DOE Office of Scientific and Technical Information (OSTI.GOV)
Yamanaka, Takamitsu; Kyono, Atsushi; Nakamoto, Yuki
2015-08-01
A structural change in Fe2SiO4 spinel (ringwoodite) has been found by synchrotron powder diffraction study and the structure of a new high-pressure phase was determined by Monte-Carlo simulation method and Rietveld profile fitting of X-ray diffraction data up to 64 GPa at ambient temperature. A transition from the cubic spinel structure to a body centered orthorhombic phase (I-Fe2SiO4) with space group Imma and Z = 4 was observed at approximately 34 GPa. The structure of I-Fe2SiO4 has two crystallographically independent FeO6 octahedra. Iron resides in two different sites of sixfold coordination: Fe1 and Fe2, which are arranged in layers parallelmore » to (101) and (011) and are very similar to the layers of FeO6 octahedra in the spinel structure. Silicon is located in the sixfold coordination in I-Fe2SiO4. The transformation to the new high-pressure phase is reversible under decompression at ambient temperature. A martensitic transformation of each slab of the spinel structure with translation vector Embedded Image generates the I-Fe2SiO4 structure. Laser heating of I-Fe2SiO4 at 1500 K results in a decomposition of the material to rhombohedral FeO and SiO2 stishovite. FeKβ X-ray emission measurements at high pressure up to 65 GPa show that the transition from a high spin (HS) to an intermediate spin (IS) state begins at 17 GPa in the spinel phase. The IS electron spin state is gradually enhanced with pressure. The Fe2+ ion at the octahedral site changes the ion radius under compression at the low spin, which results in the changes of the lattice parameter and the deformation of the octahedra of the spinel structure. The compression curve of the lattice parameter of the spinel is discontinuous at ~20 GPa. The spin transition induces an isostructural change.« less
Oyekunle, J A O; Akindolani, O A; Sosan, M B; Adekunle, A S
2017-01-01
Levels of organochlorine pesticides (OCPs) were determined in dried cocoa beans obtained from cocoa produce stores at Ondo and Ile-Ife, Southwestern Nigeria. Cocoa beans samples were sun dried to a constant weight, pulverized and soxhlet extracted with dichloromethane to obtain the OCPs. Qualitative identification and quantitative evaluation of the extracted OCPs after clean-up on silica gel were accomplished with the aid of a Gas Chromatography coupled with an Electron Capture Detector (GC-ECD). Levels of OCPs in cocoa beans from Ondo had a mean range of ND (p, p'-DDE) to 82.17 ± 54.53 ng/g (p, p'-DDT) were higher than the OCPs levels in cocoa beans from Ile-Ife with a mean range of 0.37 ± 0.63 ng/g (Endrin) to 57.76 ± 81.48 ng/g (p, p'-DDT). The higher levels of OCPs detected in the cocoa beans from Ondo could be an indication of higher volume of OCPs application by cocoa farmers in Ondo and its environs since cocoa plantations were more concentrated than Ile-Ife environs. Levels of OCPs determined in the cocoa beans were within the Maximum Residue Limit (MRLs) for OCPs set by the World Health Organization/Food and Agricultural Organization. The study established the presence of OCPs in an important crop of Nigeria. Hence, there is the need to keep monitoring ecotoxicological chemical substances in agricultural food products of Nigeria so as to take steps that ensure health safety of end users.
Planned vaginal delivery versus Caesarean section for breech presentation in Ile-Ife, Nigeria.
Orji, E O; Ajenifuja, K O
2003-11-01
The optimum mode of breech delivery remains a matter of controversy among obstetricians worldwide. To determine whether term breech babies born by planned vaginal delivery are at higher risk of neonatal mortality and morbidity than those born by planned caesarean delivery. A hospital based non-experimental comparison of outcome of breech delivery. Ife State Hospitals Complex, Ile-Ife. Two hundred and fourty four singleton breech deliveries occurring at term. They include low 5-minute Apgar score, birth trauma, maternal and perinatal morbidity and mortality. The perinatal mortality was not significantly different in both groups: OR 2.7 (95% C.I. 0.3-26.8). The low 5-minute Apgar scores were higher in the planned vaginal delivery OR 9.0 (95% C.I. 1-73.4), but the traumatic morbidity was not (OR 1.8, 95% C.I. 0.2-20.1). Maternal morbidity occurred more in the planned Caesarean delivery group OR 0.4 (95% C.I. 0.2-0.9). Given appropriate selection criteria and management protocol, the outcome from elective caesarean section might not be better than from planned vaginal delivery.
Process Model of A Fusion Fuel Recovery System for a Direct Drive IFE Power Reactor
NASA Astrophysics Data System (ADS)
Natta, Saswathi; Aristova, Maria; Gentile, Charles
2008-11-01
A task has been initiated to develop a detailed representative model for the fuel recovery system (FRS) in the prospective direct drive inertial fusion energy (IFE) reactor. As part of the conceptual design phase of the project, a chemical process model is developed in order to observe the interaction of system components. This process model is developed using FEMLAB Multiphysics software with the corresponding chemical engineering module (CEM). Initially, the reactants, system structure, and processes are defined using known chemical species of the target chamber exhaust. Each step within the Fuel recovery system is modeled compartmentally and then merged to form the closed loop fuel recovery system. The output, which includes physical properties and chemical content of the products, is analyzed after each step of the system to determine the most efficient and productive system parameters. This will serve to attenuate possible bottlenecks in the system. This modeling evaluation is instrumental in optimizing and closing the fusion fuel cycle in a direct drive IFE power reactor. The results of the modeling are presented in this paper.
NASA Astrophysics Data System (ADS)
Yang, Ji; Lin, Zheng-Zhong; Nur, A.-Zha; Lu, Yan; Wu, Ming-Hui; Zeng, Jun; Chen, Xiao-Mei; Huang, Zhi-Yong
2018-02-01
A novel fluorescence-based sensor combining synchronous fluorescence spectroscopy (SFS) with molecularly imprinted polymers (MIPs) was fabricated with reverse microemulsion method. Tetracycline (TC), (3-aminopropyl) triethoxysilane (APTES), tetraethyl orthosilicate (TEOS) and carbon quantum dots (CDs) were used as template, functional monomer, cross-linker and signal sources respectively in the probe preparation. A synchronous fluorescence emission (λem) at 355 nm was observed for the prepared MIP-coated CDs (MIP@CDs) particles when the wavelength interval (Δλ) was set as 70 nm, and the synchronous fluorescence intensity could be rapidly and efficiently quenched by TC based on inner filter effect (IFE). The quenching efficiencies of synchronous fluorescence intensity was linearly fitted with tetracycline (TC) concentrations ranging from 0.1 to 50 μmol L- 1 with a detection limit (DL) of 9 nmol L- 1 (3σ, n = 9). The MIP@CDs was used as a probe to detect TC in fish samples with the recoveries ranging from 98.4% to 103.1% and the relative standard deviation less than 6.0%. The results illustrated that the as-prepared MIP@CDs could be applied to the detection of trace TC in fish samples with rapidity, high sensitivity and accuracy.
NASA Astrophysics Data System (ADS)
Guo, Mao Xia; Yang, Liu; Jiang, Zhong Wei; Peng, Zhe Wei; Li, Yuan Fang
2017-12-01
The novel class of luminescent Al3 +-based metal-organic gels (Al-MOGs) have been developed by mix 4-[2,2‧:6‧,2″-terpyridine]-4‧-ylbenzoic acid (Hcptpy) with Al3 + under mild condition. The as-prepared Al-MOGs have not only multiple stimuli-responsive properties, but selective recognition of hydroxyl nitro aromatic compounds, which can quench the fluorescence of the Al-MOGs, while other nitro aromatic analogues without hydroxyl substitutes cannot. The fluorescence of Al-MOGs at 467 nm was seriously quenched by picric acid (PA) whose lowest unoccupied molecular orbital (LUMO) energy levels are lower than those of three other hydroxyl nitro aromatic compounds including 4-nitrophenol (4-NP), 3,5-dinitrosalicylic acid (3,5-DNTSA) and 2,4-dinitrophenol (2,4-DNP). Thus, PA was chosen as a model compound under optimal conditions and the relative fluorescence intensity of Al-MOGs was proportional to the concentration of PA in the range of 5.0-320.0 μM with a detection limit of 4.64 μM. Furthermore, the fluorescence quenching mechanism has also been investigated and revealed that the quenching was attributed to inner filter effects (IFEs), as well as electron transfer (ET) between Al-MOGs and PA.
Guo, Mao Xia; Yang, Liu; Jiang, Zhong Wei; Peng, Zhe Wei; Li, Yuan Fang
2017-12-05
The novel class of luminescent Al 3+ -based metal-organic gels (Al-MOGs) have been developed by mix 4-[2,2':6',2″-terpyridine]-4'-ylbenzoic acid (Hcptpy) with Al 3+ under mild condition. The as-prepared Al-MOGs have not only multiple stimuli-responsive properties, but selective recognition of hydroxyl nitro aromatic compounds, which can quench the fluorescence of the Al-MOGs, while other nitro aromatic analogues without hydroxyl substitutes cannot. The fluorescence of Al-MOGs at 467nm was seriously quenched by picric acid (PA) whose lowest unoccupied molecular orbital (LUMO) energy levels are lower than those of three other hydroxyl nitro aromatic compounds including 4-nitrophenol (4-NP), 3,5-dinitrosalicylic acid (3,5-DNTSA) and 2,4-dinitrophenol (2,4-DNP). Thus, PA was chosen as a model compound under optimal conditions and the relative fluorescence intensity of Al-MOGs was proportional to the concentration of PA in the range of 5.0-320.0μM with a detection limit of 4.64μM. Furthermore, the fluorescence quenching mechanism has also been investigated and revealed that the quenching was attributed to inner filter effects (IFEs), as well as electron transfer (ET) between Al-MOGs and PA. Copyright © 2017 Elsevier B.V. All rights reserved.
NOVEL MECHANISMS FOR THE VITAMIN D RECEPTOR (VDR) IN THE SKIN AND IN SKIN CANCER
Bikle, Daniel D.; Oda, Yuko; Tu, Chia-Ling; Jiang, Yan
2014-01-01
The VDR acting with or without its principal ligand 1,25(OH)2D regulates two central processes in the skin, interfollicular epidermal (IFE) differentiation and hair follicle cycling (HFC). Calcium is an important co-regulator with 1,25(OH)2 D at least of epidermal differentiation. Knockout of the calcium sensing receptor (CaSR) in addition to VDR accelerates the development of skin cancer in mice on a low calcium diet. Coactivators such as Mediator 1 (aka DRIP205) and steroid receptor coactivator 3 (SRC3) regulate VDR function at different stages of the differentiation process, with Med1 essential for hair follicle differentiation and early stages of epidermal differentiation and proliferation and SRC3 essential for the latter stages of differentiation including formation of the permeability barrier and innate immunity. The corepressor of VDR, hairless (HR), is essential for hair follicle cycling, although its effect on epidermal differentiation in vivo is minimal. In its regulation of HFC and IFE VDR controls two pathways—wnt/β-catenin and sonic hedgehog (Shh). In the absence of VDR these pathways are overexpressed leading to tumor formation. Whereas VDR binding to β-catenin may block its activation of TCF/LEF1 sites, β-catenin binding to VDR may enhance its activation of VDREs. 1,25(OH)2D promotes but may not be required for these interactions. Suppression of Shh expression by VDR, on the other hand, requires 1,25(OH)2D. The major point of emphasis is that the role of VDR in the skin involves a number of novel mechanisms, both 1,25(OH)2D dependent and independent, that when disrupted interfere with IFE differentiation and HFC, predisposing to cancer formation. PMID:25445917
Report for Task 8.4: Development of Control Room Layout Recommendations
DOE Office of Scientific and Technical Information (OSTI.GOV)
McDonald, Robert
Idaho National Laboratory (INL) has contracted Institutt for Energiteknikk (IFE) to support in the development of an end state vision for the US Nuclear industry and in particular for a utility that is currently moving forward with a control room modernization project. This support includes the development of an Overview display and technical support in conducting an operational study. Development of operational scenarios to be conducted using a full scope simulator at the INL HSSL. Additionally IFE will use the CREATE modelling tool to provide 3-D views of the potential and possible end state view after the completion of digitalmore » upgrade project.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Meier, W. R.; Bieri, R. L.; Monsler, M. J.
1992-03-01
This is a comprehensive design study of two Inertial Fusion Energy (IFE) electric power plants. Conceptual designs are presented for a fusion reactor (called Osiris) using an induction-linac heavy-ion beam driver, and another (called SOMBRERO) using a KrF laser driver. The designs covered all aspects of IFE power plants, including the chambers, heat transport and power conversion systems, balance-of-plant facilities, target fabrication, target injection and tracking, as well as the heavy-ion and KrF drivers. The point designs were assessed and compared in terms of their environmental & safety aspects, reliability and availability, economics, and technology development needs.
A new approach for rapid detection and typing of serum monoclonal components.
Cacoub, P; Camproux, A C; Thiolières, J M; Assogba, U; Hausfater, P; Mallet, A; Foglietti, M J; Piette, J C; Bernard, M
2000-12-01
When used independently, none of the routine methods to explore serum monoclonal components (MC), including: serum protein electrophoresis (SPE), immunoelectrophoresis (IEP), kappa to lambda ratio (KLR) and immunofixation (IFE), provides a comprehensive quantitative and qualitative identification of the MC. In the past few years the concept of 'protein profile', based on immunonephelometric quantifications of serum proteins, has become widely used. It consists of a qualitative and quantitative graphic representation of numerous serum proteins including immunoglobulins. Aim of study was to develop a multidimensional model based exclusively on protein profiles labeled the protein profile prediction method (PPPM) to improve routine MC detection and typing. Serum samples from 127 hospitalized patients and 99 healthy blood donors were submitted to all of the following: SPE, IFE, KLR and a protein profile (which included IgM, IgA, IgG, kappa and lambda chain detections and quantification). The presence of a MC using IFE was chosen as the gold standard. Healthy donors and patients were randomly divided into two groups defined as testing and validation groups. A logistic model was designed based on the protein profiles of the testing group leading to the determination of a threshold value (called Z(r)) for MC detection. It was then tested to detect MC in the validation group. Using IFE, 73 MC were found in the 127 hospitalized patients. Using the threshold value for MC detection of Z(r)=1.86, the PPPM showed greater sensitivity (94.6%) in detecting a MC compared to either SPE (64.8%) or KLR (89.2%). This result was obtained without diminished specificity (80.8%). The association of SPE or KLR to PPPM did not significantly increase the sensitivity of the PPPM. In the validation group, for samples which had a high predictive probability of a MC using PPPM, the correct MC typing was identified in up to 77% of sera using PPPM only. These results may be interesting in helping to determine when supplementary IFE analysis is required to qualitatively analyze a MC. PPPM allows MC detection with great sensitivity. The immune protein profile dramatically increases the sensitivity of either SPE and/or KLR in detecting MC and may also allow heavy and light chain typing.
The Light Ion Pulsed Power Induction Accelerator for ETF
1995-07-01
the technical development necessary to demonstrate scientific and engineering feasibility for fusion energy production with a reprated driver. In...order for ETF to be cost effective, the accelerator system must be able to drive several target chambers which will test various Inertial Fusion ... Energy (IFE) reactor technologies. We envision an elevator system positioning and removing multiple target chambers from the center area of the ion beam
The HALNA project: Diode-pumped solid-state laser for inertial fusion energy
NASA Astrophysics Data System (ADS)
Kawashima, T.; Ikegawa, T.; Kawanaka, J.; Miyanaga, N.; Nakatsuka, M.; Izawa, Y.; Matsumoto, O.; Yasuhara, R.; Kurita, T.; Sekine, T.; Miyamoto, M.; Kan, H.; Furukawa, H.; Motokoshi, S.; Kanabe, T.
2006-06-01
High-enery, rep.-rated, diode-pumped solid-state laser (DPSSL) is one of leading candidates for inertial fusion energy driver (IFE) and related laser-driven high-field applications. The project for the development of IFE laser driver in Japan, HALNA (High Average-power Laser for Nuclear Fusion Application) at ILE, Osaka University, aims to demonstrate 100-J pulse energy at 10 Hz rep. rate with 5 times diffraction limited beam quality. In this article, the advanced solid-state laser technologies for one half scale of HALNA (50 J, 10 Hz) are presented including thermally managed slab amplifier of Nd:phosphate glass and zig-zag optical geometry, and uniform, large-area diode-pumping.
Lasing characteristics of gas mixtures involving UFG: Application to nuclear pumping of lasers
NASA Technical Reports Server (NTRS)
Verdeyen, J. T.; Eden, J. G.
1980-01-01
Intense blue-green fluorescence from a structured band centered at lambda approximately 484 nm was observed from Ar, CF3I and NF3 gas mixtures excited by an electron beam. This emission was tentatively assigned to the E yields A transition of the iodine monofluoride (IF) molecule. The fluorescence efficiency of the IF(E yields A) band and the IF (E) state radiative lifetime were estimated to be approximately 6% and 15 ns, respectively. The emission band structure, the short IF(E) radiative lifetime and the Franck-Condon shift between the E and A states suggest that IF is an attractive candidate for a blue-green laser.
Investigation of soils affected by burnt hospital wastes in Nigeria using PIXE.
Ephraim P, Inyang; Ita, Akpan; Eusebius I, Obiajunwa
2013-12-01
Improper management of hospital waste has been reported to be responsible for several acute outbreaks like the severe acute respiratory syndrome (SARS). In spite of these challenges, hospital wastes are sometimes not properly handled in Nigeria. To date, there has not been an adequate study on the effect and fate of burnt hospital waste on agricultural soil. The effect of burnt hospital wastes on the agricultural soil was conducted on soils sampled around farm settlement near Obafemi Awolowo University Teaching Hospital Complex, Ile-Ife, South West Nigeria. PIXE technique was employed with a 1.7 MV 5SDH Tandem Pelletron accelerator available at Centre for Energy Research and Development O.A.U Ile-Ife, Nigeria. Eleven elements- Si, Cl, K, Ca, Ti, V, Cr, Mn, Fe, Zr and Pb were detected and their concentrations and enrichment factors determined. The presence of Pb and Cl at the elevated concentrations range of (77.8 ± 3.5 - 279.6 ± 97.6 and 102.2 ± 37.4 -167.2±17.43) ppm respectively in this study, is of serious health concern because of the agricultural practices in the neighborhoods of the study sites. There is a need for proper handling of hospital and other related hazardous wastes because of the possibility of such posing serious environmental pollution problems.
Impact of intimate partner violence on anxiety and depression amongst women in Ile-Ife, Nigeria.
Mapayi, Boladale; Makanjuola, R O A; Mosaku, S K; Adewuya, O A; Afolabi, O; Aloba, O O; Akinsulore, A
2013-02-01
Research into intimate partner violence in the Nigerian environment has been limited. The objective of this study was to determine, amongst a sample of women attending the Enuwa Primary Health Care Center, Ile-Ife, the association between intimate partner violence and anxiety/depression. A descriptive cross-sectional study was conducted amongst 373 women who attended the antenatal clinic and welfare units of a primary health centre in Ile-Ife using the Composite Abuse Scale, the Hospital Anxiety and Depression Scale and a socio-demographic scale as instruments. Slightly over a third (36.7 %) reported intimate partner violence within the past year, 5.6 % had anxiety and 15.5 % were depressed. Anxiety and depression in the respondents were significantly associated with intimate partner violence. Women were ten times more likely to report being depressed and 17 times more likely to report anxiety if they were in violent relationships. This research has shown that the magnitude of intimate partner violence within the study population is comparable to those found in the developing countries. There are significant associations between intimate partner violence, anxiety and depression amongst the study population and this fact undoubtedly has implications for the mental health of the Nigerian woman.
Kim, Soo-Kyung; Jeong, Tae-Dong; Kim, So Young; Lee, Woochang; Chun, Sail; Suh, Cheol Won; Min, Won-Ki
2014-05-01
The aim of this study is to investigate the characteristics of unexpected protein bands (UPBs) in patients with multiple myeloma (MM). Individuals diagnosed with MM (n=193) were enrolled. Their medical records and IFE patterns were reviewed. Of the patients that underwent ASCT, 54% developed UPBs. The median time for UPB appearance and duration was 1.8 and 5.7months, respectively. IFE revealed 74.1% of UPBs to be of the immunoglobulin G type and 72.2% to be of the κ-type. At UPB appearance, 42.6% of patients were defined as sCR or CR, and 50.0% of the patients satisfying the CR criteria had an abnormal FLC ratio. Of the patients who developed UPBs, five relapsed. Among these, four patients showed disappearance of the previous IFE oligoclonality and reappearance of the original paraprotein at relapse. Close follow-up of UPBs is critical for evaluating MM therapeutic response and disease progression. The presence of monoclonal bands may indicate relapse of disease, but in the vast majority of cases with UPBs, it does not; instead, it most likely represents a transient phenomenon caused by the immune response. Copyright © 2014 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.
Visual functions of commercial drivers in relation to road accidents in Nigeria
Oladehinde, M. K.; Adeoye, A. O.; Adegbehingbe, B. O.; Onakoya, A. O.
2007-01-01
Objective: To determine the effects of the visual functions on the occurrence of road traffic accidents (RTA) amongst commercial drivers in Ife central local government area (LGA) of Osun state of Nigeria. Design: A cross-sectional study. Settings: Four major motor parks located at Ife Central LGA. Materials and Methods: Of the estimated 270 commercial drivers in the four major parks of the LGA, 215 consecutive drivers were interviewed and had their eyes examined. Structured questionnaires were administered by an ophthalmologist. Results: The prevalence of visual impairment (visual acuity < 6/18) in the better eye without correction was 3.3% ± 2.4 and there was a significant association between uncorrected visual acuity impairment in the better eye and RTA (P = 0.0152). Refractive error was seen in 8.4% of the drivers, but none of these wear corrective glasses. Visual field defect, abnormal stereopsis and color vision impairment did not have any significant association with RTA. Conclusion: Poor visual acuity is strongly associated with RTA amongst Nigerian commercial drivers as opposed to visual field defect, abnormal color vision and stereopsis. A significant proportion of visual impairment was due to uncorrected refractive errors. PMID:21938219
Temporal, Mauro; Canaud, Benoit; Cayzac, Witold; ...
2017-05-25
The alpha-particle energy deposition mechanism modifies the ignition conditions of the thermonuclear Deuterium-Tritium fusion reactions, and constitutes a key issue in achieving high gain in Inertial Confinement Fusion implosions. One-dimensional hydrodynamic calculations have been performed with the code Multi-IFE to simulate the implosion of a capsule directly irradiated by a laser beam. The diffusion approximation for the alpha energy deposition has been used to optimize three laser profiles corresponding to different implosion velocities. A Monte-Carlo package has been included in Multi-IFE to calculate the alpha energy transport, and in this case the energy deposition uses both the LP and themore » BPS stopping power models. Homothetic transformations that maintain a constant implosion velocity have been used to map out the transition region between marginally-igniting and high-gain configurations. Furthermore, the results provided by the two models have been compared and it is found that – close to the ignition threshold – in order to produce the same fusion energy, the calculations performed with the BPS model require about 10% more invested energy with respect to the LP model.« less
Novel mechanisms for the vitamin D receptor (VDR) in the skin and in skin cancer.
Bikle, Daniel D; Oda, Yuko; Tu, Chia-Ling; Jiang, Yan
2015-04-01
The VDR acting with or without its principal ligand 1,25(OH)2D regulates two central processes in the skin, interfollicular epidermal (IFE) differentiation and hair follicle cycling (HFC). Calcium is an important co-regulator with 1,25(OH)2D at least of epidermal differentiation. Knockout of the calcium sensing receptor (CaSR) in addition to VDR accelerates the development of skin cancer in mice on a low calcium diet. Coactivators such as mediator 1 (aka DRIP205) and steroid receptor coactivator 3 (SRC3) regulate VDR function at different stages of the differentiation process, with Med 1 essential for hair follicle differentiation and early stages of epidermal differentiation and proliferation and SRC3 essential for the latter stages of differentiation including formation of the permeability barrier and innate immunity. The corepressor of VDR, hairless (HR), is essential for hair follicle cycling, although its effect on epidermal differentiation in vivo is minimal. In its regulation of HFC and IFE VDR controls two pathways-wnt/β-catenin and sonic hedgehog (SHH). In the absence of VDR these pathways are overexpressed leading to tumor formation. Whereas, VDR binding to β-catenin may block its activation of TCF/LEF1 sites, β-catenin binding to VDR may enhance its activation of VDREs. 1,25(OH)2D promotes but may not be required for these interactions. Suppression of SHH expression by VDR, on the other hand, requires 1,25(OH)2D. The major point of emphasis is that the role of VDR in the skin involves a number of novel mechanisms, both 1,25(OH)2D dependent and independent, that when disrupted interfere with IFE differentiation and HFC, predisposing to cancer formation. This article is part of a Special Issue entitled '17th Vitamin D Workshop'. Copyright © 2014 Elsevier Ltd. All rights reserved.
Harlid, Sophia; Adgent, Margaret; Jefferson, Wendy N.; Panduri, Vijayalakshmi; Umbach, David M.; Xu, Zongli; Stallings, Virginia A.; Williams, Carmen J.; Rogan, Walter J.; Taylor, Jack A.
2016-01-01
Background: Early-life exposure to estrogenic compounds affects the development of the reproductive system in rodent models and humans. Soy products, which contain phytoestrogens such as genistein, are one source of exposure in infants fed soy formula, and they result in high serum concentrations. Objectives: Our goal was to determine whether soy exposure is associated with differential DNA methylation in vaginal cells from soy-fed infant girls. Methods: Using the Illumina HumanMethylation450 BeadChip, we evaluated epigenome-wide DNA methylation in vaginal cells from four soy formula–fed and six cow formula–fed girls from the Infant Feeding and Early Development (IFED) study. Using pyrosequencing we followed up the two most differentially methylated sites in 214 vaginal cell samples serially collected between birth and 9 months of age from 50 girls (28 soy formula–fed and 22 cow formula–fed). With a mouse model, we examined the effect of neonatal exposure to genistein on gene specific mRNA levels in vaginal tissue. Results: The epigenome-wide scan suggested differences in methylation between soy formula–fed and cow formula–fed infants at three CpGs in the gene proline rich 5 like (PRR5L) (p < 104). Pyrosequencing of the two feeding groups found that methylation levels progressively diverged with age, with pointwise differences becoming statistically significant after 126 days. Genistein-exposed mice showed a 50% decrease in vaginal Prr5l mRNA levels compared to controls. Conclusions: Girls fed soy formula have altered DNA methylation in vaginal cell DNA which may be associated with decreased expression of an estrogen-responsive gene. Citation: Harlid S, Adgent M, Jefferson WN, Panduri V, Umbach DM, Xu Z, Stallings VA, Williams CJ, Rogan WJ, Taylor JA. 2017. Soy formula and epigenetic modifications: analysis of vaginal epithelial cells from infant girls in the IFED study. Environ Health Perspect 125:447–452; http://dx.doi.org/10.1289/EHP428 PMID:27539829
Olsen, Matthew T.; Rauchfuss, Thomas B.; Wilson, Scott R.
2010-01-01
The report summarizes studies on the redox behavior of synthetic models for the [FeFe]-hydrogenases, consisting of diiron dithiolato carbonyl complexes bearing the amine cofactor and its N-benzyl derivative. Of specific interest are the causes of the low reactivity of oxidized models toward H2, which contrasts with the high activity of these enzymes for H2 oxidation. The redox and acid-base properties of the model complexes [Fe2[(SCH2)2NR](CO)3(dppv)(PMe3)]+ ([2]+ for R = H and [2′]+ for R = CH2C6H5, dppv = cis-1,2-bis(diphenylphosphino)ethylene)) indicate that addition of H2 and followed by deprotonation are (i) endothermic for the mixed valence (FeIIFeI) state and (ii) exothermic for the diferrous (FeIIFeII) state. The diferrous state is shown to be unstable with respect to coordination of the amine to Fe, a derivative of which was characterized crystallographically. The redox and acid-base properties for the mixed valence models differ strongly for those containing the amine cofactor versus those derived from propanedithiolate. Protonation of [2′]+ induces disproportionation to a 1:1 mixture of the ammonium-FeIFeI and the dication [2′]2+ (FeIIFeII). This effect is consistent with substantial enhancement of the basicity of the amine in the FeIFeI state vs the FeIIFeI state. The FeIFeI ammonium compounds are rapid and efficient H-atom donors toward the nitroxyl compound TEMPO. The atom transfer is proposed to proceed via the hydride, as indicated by the reaction of [HFe2[(SCH2)2NH](CO)2(dppv)2]+ with TEMPO. Collectively, the results suggest that proton-coupled electron-transfer pathways should be considered for H2 activation by the [FeFe]-hydrogenases. PMID:21114298
Harlid, Sophia; Adgent, Margaret; Jefferson, Wendy N; Panduri, Vijayalakshmi; Umbach, David M; Xu, Zongli; Stallings, Virginia A; Williams, Carmen J; Rogan, Walter J; Taylor, Jack A
2017-03-01
Early-life exposure to estrogenic compounds affects the development of the reproductive system in rodent models and humans. Soy products, which contain phytoestrogens such as genistein, are one source of exposure in infants fed soy formula, and they result in high serum concentrations. Our goal was to determine whether soy exposure is associated with differential DNA methylation in vaginal cells from soy-fed infant girls. Using the Illumina HumanMethylation450 BeadChip, we evaluated epigenome-wide DNA methylation in vaginal cells from four soy formula-fed and six cow formula-fed girls from the Infant Feeding and Early Development (IFED) study. Using pyrosequencing we followed up the two most differentially methylated sites in 214 vaginal cell samples serially collected between birth and 9 months of age from 50 girls (28 soy formula-fed and 22 cow formula-fed). With a mouse model, we examined the effect of neonatal exposure to genistein on gene specific mRNA levels in vaginal tissue. The epigenome-wide scan suggested differences in methylation between soy formula-fed and cow formula-fed infants at three CpGs in the gene proline rich 5 like ( PRR5L ) ( p < 10 4 ). Pyrosequencing of the two feeding groups found that methylation levels progressively diverged with age, with pointwise differences becoming statistically significant after 126 days. Genistein-exposed mice showed a 50% decrease in vaginal Prr5l mRNA levels compared to controls. Girls fed soy formula have altered DNA methylation in vaginal cell DNA which may be associated with decreased expression of an estrogen-responsive gene. Citation: Harlid S, Adgent M, Jefferson WN, Panduri V, Umbach DM, Xu Z, Stallings VA, Williams CJ, Rogan WJ, Taylor JA. 2017. Soy formula and epigenetic modifications: analysis of vaginal epithelial cells from infant girls in the IFED study. Environ Health Perspect 125:447-452; http://dx.doi.org/10.1289/EHP428.
NASA Astrophysics Data System (ADS)
Lai, Hairong; Russell, Christopher; Jia, Yingdong; Wei, Hanying; Connors, Martin
2015-04-01
It is estimated that over 99% of near-Earth objects (NEOs) with diameters of about tens of meters are undiscovered. However, simulations show that they result in the most damage per year. Many of these bodies, produced in non-destructive collisions with larger well-characterized NEOs, are co-orbiting with their parent objects. Thereafter, scattering will occur due to gravitational perturbations when the co-orbiters have close encounters to any planets. Such gravitational scattering may not affect the orbits of the parent body. Therefore "safe" NEOs which have negligible impact probability with the Earth may be accompanied by potentially hazardous co-orbiting material. Those co-orbitals do reveal their existence in collisions with meteoroids, which are numerous and can be as small as tens of centimeters in diameter. Clouds of fine dust/gas particles released in such collisions become charged after generation and interact coherently with the solar wind electromagnetically. The interplanetary magnetic field is then perturbed. The resultant structures have been called interplanetary field enhancements (IFEs). They are readily identified when they pass spacecraft equipped with magnetometers. Although the co-orbitals responsible for the IFEs were disrupted in collisions, they are valid samples of the remaining co-orbiting material. Therefore, we can use IFEs to identify the spatial and mass distribution of such co-orbitals. With statistical studies of IFE occurrence, we identified asteroid 2201 Oljato and asteroid 138175 to have such co-orbiting material. The mass of the co-orbitals can be inferred by combining the results from observations and MHD simulations. Multi-spacecraft simultaneous observations measure the dimensions of the magnetic perturbations and the forces lifting them away from the Sun, while multi-fluid simulations give the accelerations of the perturbations. In summary, our technique not only helps us to identify which NEOs are accompanied by hazardous co-orbitals, but also gives their mass distributions. Although our technique provides only the statistical properties, it indicates where high resolution optical surveys should be obtained in order to identify and track specific hazardous bodies.
Ionospheric Irregularities: Source, Structure, Plasma Processes and Effects on Sensor Systems
1989-10-31
modified by using y - ye + w sin 0 sin 0 (20h) some of M orf et al.’s ideas. Fougere [1981] added a set of subroutines which find for each channel, the...correlation analysis has employed the modified Fedor algo- rithm (Fedor. 1967. CFB, this issue]. 3. ALGORITHM FOR THE SPECTRAL ANALYSIS The elements of the...knowledge, this paper presents with the every 240 m along the orbital track [Ifeelis et al., 1981]. Thus above data set the most detailed analysis of
DOE Office of Scientific and Technical Information (OSTI.GOV)
Davison, Claire C.
1972-09-01
Glass beads from archaeological sites of sub-Saharan Africa were analyzed by neutron activation and by X-ray fluorescence, and the results interpreted archaeologically. The glass beads from Igbo Ukwu (Nigeria), dated approximately to the ninth century A.D., were mostly soda-lime glasses, but a few potassium glasses were found. The glass artifacts from Ife (Nigeria), dated to approximately the tenth to twelfth centuries A.D., were mostly potassium glasses , with some soda-lime glasses. Some close resemblances were found between the glasses of the two sites . Evidence for glassworking which exists at Ife is interpreted as evidence of reworking, rather than manufacturemore » from raw materials. A European provenience is suggested for the potassium glasses, but the provenience of the soda-lime glasses i s unclear.« less
NASA Astrophysics Data System (ADS)
Orth, C. D.
2001-03-01
This paper reviews our current understanding of the relative advantages of direct drive (DD) and indirect drive (ID) for a 1 GWe inertial fusion energy (IFE) power plant driven by a diode-pumped solid-state laser (DPSSL). This comparison is motivated by a recent study (1) that shows that the projected cost of electricity (COE) for DD is actually about the same as that for ID even though the target gain for DD can be much larger. We can therefore no longer assume that DD is the ultimate targeting scenario for IFE, and must begin a more rigorous comparison of these two drive options. The comparison begun here shows that ID may actually end up being preferred, but the uncertainties are still rather large.
Response to Questions on Presentation to NAS
DOE Office of Scientific and Technical Information (OSTI.GOV)
Meier, W R
2011-03-17
Response to questions on the presentation 'Overview to Chamber and Power Plant Designs for IFE' made at the 1/29-31 meeting of the National Academies Committee on the Prospects for Inertial Confinement Fusion Energy Systems.
Campbell, John P; Cobbold, Mark; Wang, Yanyun; Goodall, Margaret; Bonney, Sarah L; Chamba, Anita; Birtwistle, Jane; Plant, Timothy; Afzal, Zaheer; Jefferis, Roy; Drayson, Mark T
2013-05-31
Monoclonal κ and λ immunoglobulin free light chain (FLC) paraproteins in serum and urine are important markers in the diagnosis and monitoring of B cell dyscrasias. Current nephelometric and turbidimetric methods that use sheep polyclonal antisera to quantify serum FLC have a number of well-observed limitations. In this report, we describe an improved method using specific mouse anti-human FLC monoclonal antibodies (mAbs). Anti-κ and anti-λ FLC mAbs were, separately, covalently coupled to polystyrene Xmap® beads and assayed, simultaneously, in a multi-plex format by Luminex® (mAb assay). The mAbs displayed no cross-reactivity to bound LC, the alternate LC type, or other human proteins and had improved sensitivity and specificity over immunofixation electrophoresis (IFE) and Freelite™. The assay gives good linearity and sensitivity (<1 mg/L), and the competitive inhibition format gave a broad calibration curve up to 437.5 mg/L and prevented anomalous results for samples in antigen excess i.e. high FLC levels. The mAbs displayed good concordance with Freelite™ for the quantitation of normal polyclonal FLC in plasma from healthy donors (n=249). The mAb assay identified all monoclonal FLC in serum from consecutive patient samples (n=1000; 50.1% with monoclonal paraprotein by serum IFE), and all FLC in a large cohort of urine samples tested for Bence Jones proteins (n=13090; 22.8% with monoclonal κ, 9.0% with monoclonal λ, and 0.8% with poly LC detected by urine IFE). Importantly this shows that the mAbs are at least close to the ideal of detecting FLC from all patients and neoplastic plasma cell clones. Given the overall effectiveness of the anti-FLC mAbs, further clinical validation is now warranted on serial samples from a range of patients with B cell disorders. Use of these mAbs on other assay platforms should also be investigated. Copyright © 2013 Elsevier B.V. All rights reserved.
The Mercury Project: A High Average Power, Gas-Cooled Laser For Inertial Fusion Energy Development
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bayramian, A; Armstrong, P; Ault, E
Hundred-joule, kilowatt-class lasers based on diode-pumped solid-state technologies, are being developed worldwide for laser-plasma interactions and as prototypes for fusion energy drivers. The goal of the Mercury Laser Project is to develop key technologies within an architectural framework that demonstrates basic building blocks for scaling to larger multi-kilojoule systems for inertial fusion energy (IFE) applications. Mercury has requirements that include: scalability to IFE beamlines, 10 Hz repetition rate, high efficiency, and 10{sup 9} shot reliability. The Mercury laser has operated continuously for several hours at 55 J and 10 Hz with fourteen 4 x 6 cm{sup 2} ytterbium doped strontiummore » fluoroapatite (Yb:S-FAP) amplifier slabs pumped by eight 100 kW diode arrays. The 1047 nm fundamental wavelength was converted to 523 nm at 160 W average power with 73% conversion efficiency using yttrium calcium oxy-borate (YCOB).« less
Heavy metals in industrially emitted particulate matter in Ile-Ife, Nigeria.
Ogundele, Lasun T; Owoade, Oyediran K; Hopke, Philip K; Olise, Felix S
2017-07-01
Iron and steel smelting facilities generate large quantities of airborne particulate matter (PM) through their various activities and production processes. The resulting PM that contains a variety of heavy metals has potentially detrimental impacts on human health and the environment. This study was conducted to assess the potential health effects of the pollution from the heavy metals in the airborne PM sampled in the vicinity of secondary smelting operations in Ile-Ife, Nigeria. X-ray fluorescence (XRF) was used to determine the elemental concentration of Pb, Cr, Cd, Zn, Mn, As, Fe, Cu, and Ni in the size-segregated PM samples. Pollution Indices (PI) consisting of Contamination Factor (CF), Degree of Contamination (DC) and Pollution Index Load (PLI) and Target Hazard Quotient (THQ) were employed to assess the pollution risk associated with the heavy metals in the PM. CF, DC and PLI values were 3< CF <6, >32 and >1, respectively for the three sites, indicating deterioration of the ambient air quality in the vicinity of the smelter. The heavy metals in the airborne PM pose a severe health risk to people living in vicinity of the facility and to its workers. The diminished air quality with the associated health risks directly depends on the industrial emissions from steel production and control measures are recommended to mitigate the likely risks. Copyright © 2017 Elsevier Inc. All rights reserved.
NASA Astrophysics Data System (ADS)
Temporal, Mauro; Canaud, Benoit; Cayzac, Witold; Ramis, Rafael; Singleton, Robert L.
2017-05-01
The alpha-particle energy deposition mechanism modifies the ignition conditions of the thermonuclear Deuterium-Tritium fusion reactions, and constitutes a key issue in achieving high gain in Inertial Confinement Fusion implosions. One-dimensional hydrodynamic calculations have been performed with the code Multi-IFE [R. Ramis, J. Meyer-ter-Vehn, Comput. Phys. Commun. 203, 226 (2016)] to simulate the implosion of a capsule directly irradiated by a laser beam. The diffusion approximation for the alpha energy deposition has been used to optimize three laser profiles corresponding to different implosion velocities. A Monte-Carlo package has been included in Multi-IFE to calculate the alpha energy transport, and in this case the energy deposition uses both the LP [C.K. Li, R.D. Petrasso, Phys. Rev. Lett. 70, 3059 (1993)] and the BPS [L.S. Brown, D.L. Preston, R.L. Singleton Jr., Phys. Rep. 410, 237 (2005)] stopping power models. Homothetic transformations that maintain a constant implosion velocity have been used to map out the transition region between marginally-igniting and high-gain configurations. The results provided by the two models have been compared and it is found that - close to the ignition threshold - in order to produce the same fusion energy, the calculations performed with the BPS model require about 10% more invested energy with respect to the LP model.
Index of the Relative Importance of Fuel Efficiency (IFE) in the Motor Vehicle Market
DOT National Transportation Integrated Search
1981-10-01
The need for the National Highway Traffic Safety Administration to understand the importance of vehicle fuel economy in the marketplace has created the requirement for a quantitative measure of consumer attitudes toward fuel efficiency. This paper su...
Chronic Airflow Obstruction in a Black African Population: Results of BOLD Study, Ile-Ife, Nigeria.
Obaseki, Daniel O; Erhabor, Gregory E; Gnatiuc, Louisa; Adewole, Olufemi O; Buist, Sonia A; Burney, Peter G
2016-01-01
Global estimates suggest that Chronic Obstructive Pulmonary Disease (COPD) is emerging as a leading cause of death in developing countries but there are few spirometry-based general population data on its prevalence and risk factors in sub-Saharan Africa. We used the Burden of Obstructive Lung Disease (BOLD) protocol to select a representative sample of adults aged 40 years and above in Ile-Ife, Nigeria. All the participants underwent spirometry and provided information on smoking history, biomass and occupational exposures as well as diagnosed respiratory diseases and symptoms. Chronic Airflow Obstruction (CAO) was defined as the ratio of post-bronchodilator (BD) one second Forced Expiratory Volume (FEV1) to Forced Vital Capacity (FVC) below the lower limit of normal (LLN) of the population distribution for FEV1/FVC. The overall prevalence of obstruction (post-BD FEV1/FVC < LLN) was 7.7% (2.7% above LLN) using Global Lung Function Initiative (GLI) equations. It was associated with few respiratory symptoms; 0.3% reported a previous doctor-diagnosed chronic bronchitis, emphysema or COPD. Independent predictors included a lack of education (OR 2.5, 95% CI: 1.0, 6.4) and a diagnosis of either TB (OR 23.4, 95% CI: 2.0, 278.6) or asthma (OR 35.4, 95%CI: 4.9, 255.8). There was no association with the use of firewood or coal for cooking or heating. The vast majority of this population (89%) are never smokers. We conclude that the prevalence of CAO is low in Ile-Ife, Nigeria and unrelated to biomass exposure. The key independent predictors are poor education, and previous diagnosis of tuberculosis or asthma.
NASA Astrophysics Data System (ADS)
Zhang, Shuming; Lin, Bixia; Yu, Ying; Cao, Yujuan; Guo, Manli; Shui, Lingling
2018-04-01
Ratiometric fluorescent probes could eliminate the influence from experimental factors and improve the detection accuracy. In this article, a ratiometric nanoprobe was constructed based on silver nanoclusters (AgNCs) with nitrogen-doped carbon dots (NCDs) and used for the detection of biothiols. The fluorescence peak of AgNCs was observed at 650 nm with excitation wavelength at 370 nm. In order to construct the ratiometric fluorescent probe, NCDs with the excitation and emission wavelengths at 370 nm and 450 nm were selected. After adding AgNCs, the fluorescence of NCDs was quenched. The mechanism of the fluorescence quenching was studied by fluorescence, UV-Vis absorption and the fluorescence lifetime spectra. The results indicated that the quenching could be ascribed to the inner filter effect (IFE). With the addition of biothiols, the fluorescence of AgNCs at 650 nm decreased due to the breakdown of AgNCs, and the fluorescence of NCDs at 450 nm recovered accordingly. Thus, the relationship between the ratio of the fluorescence intensities (I450/I650) and biothiol concentration was used to establish the determination method for biothiols. Cysteine (Cys) was taken as the model of biothiols, and the working curve for Cys was I450/I650 = 0.60CCys - 1.86 (CCys: μmol/L) with the detection limit of 0.14 μmol/L (S/N = 3). Then, the method was used for the detection of Cys in human urine and serum samples with satisfactory accuracy and recovery ratios. Furthermore, the probe could be applied for the visual semi-quantitative determination of Cys by naked eyes.
LIFE CYCLE DESIGN FRAMEWORK AND DEMONSTRATION PROJECTS PROFILES OF AT&T AND ALLIED SIGNAL
Life cycle design seeks to minimize the environmental burden associated with a product life cycle from raw materials acquisition through manufacturing, use, and end-of-life management. ife cycle design emphasizes integrating environmental requirements into the earliest phases of ...
Search Techniques for Self-Organizing Systems
1975-07-01
according to their associated function values. The classes need not have equal function value ranges (i.e., the . ................... "The Mucciardi- Gose ... Gose , "An Automatic Clustering Algorithm and Its !’ropertizs in High-Dimensional Spaces,’[ IFEE Trans. S s~tems, Man and Cybernetics, Vol. SMC-2
Subtask 12D3: Fracture properties of V-5Cr-5Ti Alloy
DOE Office of Scientific and Technical Information (OSTI.GOV)
Li, H.; Hamilton, M.L.; Jones, R.H.
1995-03-01
The purpose of this research is to investigate the effect of heat treatment on microstructure and fracture toughness of a V-5Cr-5Ti alloy in the range -50-100{degrees}C. Fracture toughness and impact tests were performed on a V-5Cr-5Ti alloy. Specimens annealed at 1125{degrees}C for 1 h and furnace cooled in a vacuum of 1.33 x 10{sup -5} Pa were brittle at room temperature (RT) and experienced a mixture of intergranular and cleavage fracture. Fracture toughness (J{sub IQ}) at RT was 52 kJ/m{sup 2} and the impact fracture energy (IFE) was 6 J. The IFE at -100{degrees}C was only 1 J. While specimensmore » exhibited high fracture toughness at 100{degrees}C (J{sub IQ} is 485 kj/m{sup 2}), fracture was a mixture of dimple and intergranular failure, with intergranular fracture making up 40% of the total fracture surface. The ductile to brittle transition temperature (DBTT) was estimated to be about 20{degrees}C. When some specimens were given an additional annealing at 890{degrees}C for 24 h, they became very ductile at RT and fractured by microvoid coalescence. The J{sub IQ} value increased from 52 kJ/m{sup 2} to {approximately}1100 kJ/m{sup 2}. The impact test failed to fracture specimens at RT due to a large amount of plastic deformation. 7 refs., 1 fig., 6 tabs.« less
75 FR 65017 - Ocean Transportation Intermediary License Revocations
Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-21
...: 6701 Moravia Park Drive, Unit B, Baltimore, MD 21237. Date Revoked: September 17, 2010. Reason: Failed.... License Number: 018717N. Name: IFE Global Logistics Inc. Address: 100 North Hill Drive, 16, Brisbane, CA... Logistics Inc. Address: 1001 Nicholas Blvd., A, Elk Grove Village, IL 60007. Date Revoked: September 10...
Ogundele, Olorunfemi Akinbode; Ogundele, Tolulope
2015-01-01
Childhood malnutrition remains a widespread problem in developing world like Nigeria. The country ranks second among the ten countries contributing to sixty percent of the world's wasted under-five children. Community Integrated Management of Childhood illness (CIMCI) is a programme that employs the use of community based counsellors to address child health and nutritional challenges of the under-five and has the potential to reduce the morbidity and mortality resulting from poor nutritional and feeding practices. The study assessed the effect of community level intervention on nutritional status and feeding practices of children in Ile-Ife, Nigeria. A cross-sectional comparative study that employed the use of multi stage cluster sampling techniques in selecting 722 mothers of index under five children. The study was done in two Local Government Areas of Osun State, Nigeria. Quantitative techniques were used in data collection. Data analysis was done using SPSS version 20.0. Descriptive and bivariate analyses was performed. The two Local Government Area (LGA) did not differ significantly in their wealth index (p = 0.344). However, more children in the non-implementing LGA (16.1%) had low weight for age compared with 3.6% in the CIMCI implementing LGA (p = 0.000). A statistically significant difference exist in the MUAC measurement of children 12-23 months between the CIMCI implementing and non-implementing communities (p = 0.007). A higher percentage of caregivers (19.3%) introduced complementary feeding earlier than 6 months in the non-implementing area (p < 0.001). Using community level nutritional counseling can greatly improve nutritional status and feeding practices of under five children.
Critical Science Issues for Direct Drive Inertial Fusion Energy
NASA Astrophysics Data System (ADS)
Dahlburg, Jill P.; Gardner, John H.; Schmitt, Andrew J.; Obenschain, S. P.
1998-09-01
There are several topics that require resolution prior to the construction of an Inertial Fusion Energy [IFE] laboratory Engineering Test Facility [ETF]: a pellet that produces high gain; a pellet fabrication system that cost-effectively and rapidly manufactures these pellets; a sufficiently uniform and durable high repetition-rate laser pellet driver; a practical target injection system that provides accurate pellet aiming; and, a target chamber that will survive the debris and radiation of repeated high-gain pellet implosions. In this summary we describe the science issues and opportunities that are involved in the design of a successful high gain direct drive Inertial Confinement Fusion [ICF] pellet.
U.S. EPA, Pesticide Product Label, EN SURE EMULSIFIABLE CONCENTRATE INSECTICIDE, 04/18/1975
2011-04-14
... tr('atH! t'(':'j , :"nllr1 ;,.>4 hOllr') of <1J)pl, C;.Jtl'J[' "h"'JlcJ :.I:,jI ,.roll·' I .f: (ict'l:ng Thl') I,rvkr:' ", tOt,,- to ft.', dnd '1.rldllit: B,rch if:('ei;ng
Ethnic Diversity and Political Attitudes in a Nigerian University
ERIC Educational Resources Information Center
Brier, Alan; Tansey, Stephen
1974-01-01
A survey of attitudes of the student population at Nigeria's University of Ife, at the outset of the civil war in 1967, revealed the development of a common set of political attitudes among the students which are variegated but in which variations are not related to tribal origins in any fundamental aspects. (EH)
Worldwide Emerging Environmental Issues Affecting the U.S. Military, February 2011 Report
2011-02-01
Overview, presents examples of approaches that integrate food and energy crops. The paper describes two types of IFES: a) food and biomass for energy are...grown on the same land, and b) the use of agro-industrial technology that allows agricultural byproducts to be used through gasification or anaerobic
1990-02-01
procaryotic systems (12. 45). Certain eucaryotic ically cleaved by a trypsin-like proteas: ito produce a recep- viruses are currently being explored as...19847. Proteolytic activation of anthrax toxin bound to cellular recep- ACKN()WEIX;NMNTS tor%.. p. 111-112. In F. Fehrenbach et al. ifed.). Bacterial
Development of Electron Beam Pumped KrF Lasers for Fusion Energy
2008-01-01
Direct drive with krypton fluoride (KrF) lasers is an attractive approach to inertial fusion energy (IFE): KrF lasers have outstanding beam spatial...attractive power plant [3]. In view of these advances, several world-wide programs are underway to develop KrF lasers for fusion energy . These include
Pulsed Power Design for a Small Repetitively Pulsed Electron Beam Pumped KrF Laser
2003-06-01
fusion energy (IFE) requirements for rep-rate, efficiency, durability and cost. We have designed a pulsed power system for the pre-amplifier in the Electra...new advanced pulsed power topology that can meet the fusion energy requirements for durability, repetition rate, and cost. The pulsed power will first
DOE Office of Scientific and Technical Information (OSTI.GOV)
Temporal, Mauro; Canaud, Benoit; Cayzac, Witold
The alpha-particle energy deposition mechanism modifies the ignition conditions of the thermonuclear Deuterium-Tritium fusion reactions, and constitutes a key issue in achieving high gain in Inertial Confinement Fusion implosions. One-dimensional hydrodynamic calculations have been performed with the code Multi-IFE to simulate the implosion of a capsule directly irradiated by a laser beam. The diffusion approximation for the alpha energy deposition has been used to optimize three laser profiles corresponding to different implosion velocities. A Monte-Carlo package has been included in Multi-IFE to calculate the alpha energy transport, and in this case the energy deposition uses both the LP and themore » BPS stopping power models. Homothetic transformations that maintain a constant implosion velocity have been used to map out the transition region between marginally-igniting and high-gain configurations. Furthermore, the results provided by the two models have been compared and it is found that – close to the ignition threshold – in order to produce the same fusion energy, the calculations performed with the BPS model require about 10% more invested energy with respect to the LP model.« less
Magnetized Plasma Compression for Fusion Energy
NASA Astrophysics Data System (ADS)
Degnan, James; Grabowski, Christopher; Domonkos, Matthew; Amdahl, David
2013-10-01
Magnetized Plasma Compression (MPC) uses magnetic inhibition of thermal conduction and enhancement of charge particle product capture to greatly reduce the temporal and spatial compression required relative to un-magnetized inertial fusion (IFE)--to microseconds, centimeters vs nanoseconds, sub-millimeter. MPC greatly reduces the required confinement time relative to MFE--to microseconds vs minutes. Proof of principle can be demonstrated or refuted using high current pulsed power driven compression of magnetized plasmas using magnetic pressure driven implosions of metal shells, known as imploding liners. This can be done at a cost of a few tens of millions of dollars. If demonstrated, it becomes worthwhile to develop repetitive implosion drivers. One approach is to use arrays of heavy ion beams for energy production, though with much less temporal and spatial compression than that envisioned for un-magnetized IFE, with larger compression targets, and with much less ambitious compression ratios. A less expensive, repetitive pulsed power driver, if feasible, would require engineering development for transient, rapidly replaceable transmission lines such as envisioned by Sandia National Laboratories. Supported by DOE-OFES.
Olotu, Amadin A; Oyelese, Adesola O; Salawu, Lateef; Audu, Rosemary A; Okwuraiwe, Azuka P; Aboderin, Aaron O
2016-05-05
Hepatitis B virus (HBV) transmission through blood transfusion is reduced by screening for hepatitis B surface antigen (HBsAg). However this method cannot detect the presence of occult hepatitis B virus infection. This study sought to determine the prevalence of occult hepatitis B virus infection among blood donors in Ile-Ife, Nigeria. For the first time in Nigeria we employed an automated real-time PCR- method to investigate the prevalence of occult HBV in blood donors. Blood donors screened with HBsAg immunochromatographic rapid test kits at the blood transfusion units of two hospitals and found to be negative were recruited into the study. Questionnaires to elicit risk factors for HBV infection were administered and then 10 ml of blood was collected from each donor. Plasma samples obtained from these HBsAg negative blood donors were screened again for HBsAg using an enzyme-linked immunosorbent assay (ELISA) method, and those found negative were screened for the presence of total antibody to the HBV core antigen (anti-HBc) using ELISA method. Those positive to anti-HBc were then tested for HBV DNA, using an automated real-time PCR method. Five hundred and seven blood donors found HBsAg negative by immunochromatographic rapid test kits at both blood transfusion units, were tested for HBsAg using ELISA and 5 (1 %) were HBsAg positive. The 502 found negative were tested for anti-HBc and 354 (70.5 %) were found positive implying previous exposure to HBV and 19 (5.4 %) of the 354 anti-HBc positive had HBV DNA signifying occult HBV infection. No risk factors were found to be associated with the presence of HBV DNA among those who tested positive. Occult HBV infection exists in blood donors in Ile-Ife, Nigeria and the use of HBsAg alone for screening prospective donors will not eliminate the risk of HBV transmission in blood transfusion or stem cell transplantation.
The Micropolitics of School Principals' Decision Making in Nigeria: Principals' Perspective
ERIC Educational Resources Information Center
Olayiwola, Shina; Alabi, Kingsley
2015-01-01
This study depicted a micropolitical analysis of school principals' decision making as regards the influence of formal and informal groups on school administrative processes from the point of view of principals. It was based on descriptive survey study of all 24 public secondary schools within Ile-Ife community, Osun State, Nigeria, out of which a…
Prospects and Challenges of Online Guidance and Counselling Services in a Nigerian University
ERIC Educational Resources Information Center
Adebowale, Olusegun F.; Popoola, Bayode I.
2011-01-01
This study examined the prospects and challenges of online guidance and counselling services at the Obafemi Awolowo University, Ile-Ife, Nigeria. It considered students' views on the nature of and preferences for online services, and the problems that might potentially be presented in that context. It also surveyed staff in regard to assessing the…
Health Promotion Intervention for Hygienic Disposal of Children's Faeces in a Rural Area of Nigeria
ERIC Educational Resources Information Center
Jinadu, M. K.; Adegbenro, C. A.; Esmai, A. O.; Ojo, A. A.; Oyeleye, B. A.
2007-01-01
Objective: Community-based health promotion intervention for improving unhygienic disposal of children's faeces was conducted in a rural area of Nigeria. Setting: The study was conducted in Ife South Local Government area of Osun State, Nigeria. Design: The study was conducted in 10 randomly selected rural villages: five control and five active.…
Substance use Among University Undergraduates: A Study of Pattern and Beliefs in Ile-Ife.
Fatoye, F O
2007-03-01
To determine the prevalence of substance use and to investigate the relationship between psychosocial variables and current use of psychoactive substances among university undergraduates. A cross-sectional survey of randomly selected undergraduates of the Obafemi Awolowo University, Ile Ife was carried out using the WHO drug use questionnaire. Alcohol, stimulants, hypnosedatives, tobacco and cannabis with current use prevalence rates of 20.2 %, 17.7%, 9.8%, 9.0% and 8.2 % respectively were the most commonly used substances. Inhalants/organic solvents, cocaine, heroin, hallucinogens and pethidine/morphine with current use rates of 3.2%, 2.6%, 2.2%, 1.0% and 0.5% respectively belonged to the 'low - use' category. However, these rates were marginally higher than most previous findings. Five variables (sex, polygamy, living outside the university campus, poor mental health and study difficulty), were significantly associated with the use of many of the substances. Also, perceived harmfulness was observed to be a possible deterrent to substance use and most users were engaged in the use of cheap and easily available substances. The observations are largely similar to those from other locations in Nigeria and may therefore be useful in preventive programmes.
Optimal integrated abundances for chemical tagging of extragalactic globular clusters
NASA Astrophysics Data System (ADS)
Sakari, Charli M.; Venn, Kim; Shetrone, Matthew; Dotter, Aaron; Mackey, Dougal
2014-09-01
High-resolution integrated light (IL) spectroscopy provides detailed abundances of distant globular clusters whose stars cannot be resolved. Abundance comparisons with other systems (e.g. for chemical tagging) require understanding the systematic offsets that can occur between clusters, such as those due to uncertainties in the underlying stellar population. This paper analyses high-resolution IL spectra of the Galactic globular clusters 47 Tuc, M3, M13, NGC 7006, and M15 to (1) quantify potential systematic uncertainties in Fe, Ca, Ti, Ni, Ba, and Eu and (2) identify the most stable abundance ratios that will be useful in future analyses of unresolved targets. When stellar populations are well modelled, uncertainties are ˜0.1-0.2 dex based on sensitivities to the atmospheric parameters alone; in the worst-case scenarios, uncertainties can rise to 0.2-0.4 dex. The [Ca I/Fe I] ratio is identified as the optimal integrated [α/Fe] indicator (with offsets ≲ 0.1 dex), while [Ni I/Fe I] is also extremely stable to within ≲ 0.1 dex. The [Ba II/Eu II] ratios are also stable when the underlying populations are well modelled and may also be useful for chemical tagging.
NASA Astrophysics Data System (ADS)
Ogundele, Lasun T.; Olasinde, Roseline T.; Owoade, Oyediran K.; Olise, Felix S.
2018-05-01
This study presents the elemental compositions and concentrations of indoor dust and identifies the major sources in some selected indoor environments in Ile-Ife, Nigeria. The dust samples were collected from 16 indoor environments comprising offices, churches, residential and staff quarters using a cyclonic high power vacuum cleaner. The dust samples were analyzed for elemental concentrations using x-ray fluorescences. The data sets were analyzed for the possible sources and their contributions using Principal Component Factor Analysis (PCFA). The result showed that dust samples contained several elements: K, Ca, Ti, Mn, Fe, Ni, Cu, Zn, Ga, As, Rb, Sr, Se, Zr, V, and Sc. The PCFA identified three factors with the percentage variance of 92, 77, 71 and 68%, for the office, church, residential, and staff quarters, respectively, for the combined elemental data of each of the site classes. The identified sources were track-in-soil, road and windblown soil dust, paint debris, household dust from personal care materials, cooking, and cleaning activities. The unintentional track-in-soil due to mobility of the occupants, structural materials, and outdoor air was the major sources contributing to the indoor dust.
Suppression of the Rayleigh Taylor instability and its implication for the impact ignition
NASA Astrophysics Data System (ADS)
Azechi, H.; Shiraga, H.; Nakai, M.; Shigemori, K.; Fujioka, S.; Sakaiya, T.; Tamari, Y.; Ohtani, K.; Murakami, M.; Sunahara, A.; Nagatomo, H.; Nishihara, K.; Miyanaga, N.; Izawa, Y.
2004-12-01
The Rayleigh Taylor (RT) instability with material ablation through an unstable interface is the key physics that determines the success or failure of inertial fusion energy (IFE) generation, as the RT instability potentially quenches ignition and burn by disintegrating the IFE target. We present two suppression schemes of the RT growth without significant degradation of the target density. The first scheme is to generate a double ablation structure in high-Z doped plastic targets. In addition to the electron ablation surface, a new ablation surface is created by x-ray radiation from the high-Z ions. Contrary to the previous thought, the electron ablation surface is almost completely stabilized by extremely high flow velocity. On the other hand, the RT instability on the radiative ablation surface is significantly moderated. The second is to enhance the nonlocal nature of the electron heat transport by illuminating the target with long wavelength laser light, whereas the high ablation pressure is generated by irradiating with short wavelength laser light. The significant suppression of the RT instability may increase the possibility of impact ignition which uses a high-velocity fuel colliding with a preformed main fuel.
NDCX-II target experiments and simulations
Barnard, J. J.; More, R. M.; Terry, M.; ...
2013-06-13
The ion accelerator NDCX-II is undergoing commissioning at Lawrence Berkeley National Laboratory (LBNL). Its principal mission is to explore ion-driven High Energy Density Physics (HEDP) relevant to Inertial Fusion Energy (IFE) especially in the Warm Dense Matter (WDM) regime. We have carried out hydrodynamic simulations of beam-heated targets for parameters expected for the initial configuration of NDCX-II. For metal foils of order one micron thick (thin targets), the beam is predicted to heat the target in a timescale comparable to the hydrodynamic expansion time for experiments that infer material properties from measurements of the resulting rarefaction wave. We have alsomore » carried out hydrodynamic simulations of beam heating of metallic foam targets several tens of microns thick (thick targets) in which the ion range is shorter than the areal density of the material. In this case shock waves will form and we derive simple scaling laws for the efficiency of conversion of ion energy into kinetic energy of fluid flow. Geometries with a tamping layer may also be used to study the merging of a tamper shock with the end-of-range shock. As a result, this process can occur in tamped, direct drive IFE targets.« less
Adekunle, Abolanle Saheed; Oyekunle, John Adekunle Oyedele; Ojo, Oluwaseyi Samson; Maxakato, Nobanathi W; Olutona, Godwin Oladele; Obisesan, Olaoluwa Ruth
2017-01-01
This study determined the presence and levels of Polycyclic Aromatic Hydrocarbons (PAHs) of groundwater in Moro, Edun-Abon, Yakoyo and Ipetumodu communities in Ife-North Local Government Area of Osun State. This was with a view to create public awareness about the safety of groundwater as a source for domestic purposes (e.g., drinking, cooking etc.) in non-industrial area. Water samples were collected on seasonal basis, comprising of three months (August-October) in the wet season and three months (December-February) in the dry season. The PAHs in the water samples were extracted with n -hexane using liquid-liquid extraction method, while their qualitative identifications and quantitative estimations were carried out with the use of gas chromatography. Levels of PAHs detected showed predominance of light PAHs (less than four fused rings) for both wet and the dry seasons. Higher concentrations of PAHs were recorded during the wet season than the dry season. The study concluded that the groundwater in the communities was contaminated with light PAHs and the total PAHs in this area exceeded the maximum permissible limit of 10 μg L -1 recommended by World Health Organization (WHO) for safety of groundwater.
Systems Fragility: The Sociology of Chaos
2015-03-01
Science (New York, N.Y.) 302, no. 5652 (2004): 1912, doi:10.1126/science.1090847. 70 Barry Wellman, and Scot Wortley, “Different Strokes from...Michael Dombeck, Jack Williams, and Christopher Wood , “Wildfire Policy and Public Lands: Integrating Scientific Understanding with Social Concerns...bitstream/10092/2809/ 1/12593870_ResOrgs_IFED_dec04_EDSM.pdf Dombeck, Michael, Jack Williams, and Christopher Wood . “Wildfire Policy and Public
Two Strategic Decisions Facing Fusion
NASA Astrophysics Data System (ADS)
Baldwin, D. E.
1998-06-01
Two strategic decisions facing the U.S. fusion program are described. The first decision deals with the role and rationale of the tokamak within the U. S. fusion program, and it underlies the debate over our continuing role in the evolving ITER collaboration (mid-1998). The second decision concerns how to include Inertial Fusion Energy (IFE) as a viable part of the national effort to harness fusion energy.
ERIC Educational Resources Information Center
Fafunwa, A. Babs
1975-01-01
This project was launched as a medium of instruction throughout the six-year primary course, predicted on the hypotheses that the child benefits culturally, socially, linguistically and cognitively through native language instruction, and that his command of English will be improved if it is taught as a separate subject by a specially trained…
Diode-pumped solid-state laser driver experiments for inertial fusion energy applications
DOE Office of Scientific and Technical Information (OSTI.GOV)
Marshall, C.D.; Payne, S.A.; Emanuel, M.E.
Although solid-state lasers have been the primary means by which the physics of inertial confinement fusion (ICF) have been investigated, it was previously thought that solid-state laser technology could not offer adequate efficiencies for an inertial fusion energy (IFE) power plant. Orth and co-workers have recently designed a conceptual IFE power plant, however, with a high efficiency diode-pumped solid-state laser (DPSSL) driver that utilized several recent innovations in laser technology. It was concluded that DPSSLs could offer adequate performance for IFE with reasonable assumptions. This system was based on a novel diode pumped Yb-doped Sr{sub 5}(PO{sub 4}){sub 3}F (Yb:S-FAP) amplifier.more » Because this is a relatively new gain medium, a project was established to experimentally validate the diode-pumping and extraction dynamics of this system at the smallest reasonable scale. This paper reports on the initial experimental results of this study. We found the pumping dynamics and extraction cross-sections of Yb:S-FAP crystals to be similar to those previously inferred by purely spectroscopic techniques. The saturation fluence for pumping was measured to be 2.2 J/cm{sup 2} using three different methods based on either the spatial, temporal, or energy transmission properties of a Yb:S-FAP rod. The small signal gain implies an emission cross section of 6.0{times}10{sup {minus}20} cm{sup 2}. Up to 1.7 J/cm{sup 3} of stored energy density was achieved in a 6{times}6{times}44 mm{sup 3} Yb:S-FAP amplifier rod. In a free running configuration diode-pumped slope efficiencies up to 43% were observed with output energies up to {approximately}0.5 J per 1 ms pulse from a 3{times}3{times}30 mm{sup 3} rod. When the rod was mounted in a copper block for cooling, 13 W of average power was produced with power supply limited operation at 70 Hz with 500 {mu}s pulses.« less
Validating Inertial Confinement Fusion (ICF) predictive capability using perturbed capsules
NASA Astrophysics Data System (ADS)
Schmitt, Mark; Magelssen, Glenn; Tregillis, Ian; Hsu, Scott; Bradley, Paul; Dodd, Evan; Cobble, James; Flippo, Kirk; Offerman, Dustin; Obrey, Kimberly; Wang, Yi-Ming; Watt, Robert; Wilke, Mark; Wysocki, Frederick; Batha, Steven
2009-11-01
Achieving ignition on NIF is a monumental step on the path toward utilizing fusion as a controlled energy source. Obtaining robust ignition requires accurate ICF models to predict the degradation of ignition caused by heterogeneities in capsule construction and irradiation. LANL has embarked on a project to induce controlled defects in capsules to validate our ability to predict their effects on fusion burn. These efforts include the validation of feature-driven hydrodynamics and mix in a convergent geometry. This capability is needed to determine the performance of capsules imploded under less-than-optimum conditions on future IFE facilities. LANL's recently initiated Defect Implosion Experiments (DIME) conducted at Rochester's Omega facility are providing input for these efforts. Recent simulation and experimental results will be shown.
Report of the Fusion Energy Sciences Advisory Committee Panel on Priorities and Balance
NASA Astrophysics Data System (ADS)
Baker, Charles; Davidson, Ronald; Dean, Stephen; Freidberg, Jeffrey; Sheffield, John
1999-06-01
This report presents the results and recommendations of the deliberations of the DOE Fusion Energy Sciences Advisory Committee (FESAC) Panel on Priorities and Balance, which met in Knoxville, TN, 18-21 August 1999. The Panel identified the achievement of a more integrated national program in magnetic fusion energy (MFE) and inertial fusion energy (IFE) as a major programmatic and policy goal for the years ahead.
ERIC Educational Resources Information Center
Adeniyi, W. O.; Okewole, J. O.
2014-01-01
The study examined the influence of knowledge and awareness of sexually transmitted diseases on change in sexual behaviour of fresh undergraduates with a view to providing useful suggestions for positive sexual behaviour of adolescents. The study adopted the descriptive survey design. A sample of 600 fresh undergraduates was selected from the…
Paraguay: Political and Economic Conditions and U.S. Relations
2010-02-01
21.9% of the vote.8 International observation teams from the Organization of American States ( OAS ) and the U.S.-based International Foundation for...Electoral Systems (IFES) praised the successful conduct of the elections. Both groups characterized the election as historic, with the OAS ...France-Presse, September 18, 2007. 8 “Background Note: Paraguay,” January 2009. 9 OAS , “El Secretario General de la OEA Felicita Masiva y Tranquila
Correlates of Self-Report of Rape Among Male School Adolescents in Ile-Ife, Nigeria.
Ogunfowokan, Adesola A; Olagunju, Oluwayemisi E; Olajubu, Aanuoluwapo O; Faremi, Funmilola A; Oloyede, Ajoke S; Sharps, Phyllis W
2016-02-01
This study examined male adolescents' self-report of rape of adolescent girls and the socio-demographic variables that correlated with self-report of rape. Descriptive-correlational design was used and the study was conducted in five public senior secondary schools in Ile-Ife, Nigeria. Three hundred and thirty-eight male adolescents participated in the study. A structured questionnaire was used to collect data. Findings from the study revealed the mean age of the adolescent males to be 16 years, with the majority (73%) of them in the middle adolescent stage. Six percent of the adolescent males reported they had raped an adolescent girl in the past. Among the boys who reported rape, 55% reported they had raped their sexual partners, and 55% reported they had perpetrated gang rape. Smoking (p = .0001), alcohol consumption (p = .001), and birth order (p = .006) predicted self-report of rape. The coefficient of birth order showed that odds of self-report of rape by first-born male increases by 6 times compared with other children. Study findings also provided evidence that adolescent males are moving from lone rape to gang rape in intimate partner relationships. Male adolescents are important group to target in rape prevention programs. © The Author(s) 2014.
NASA Astrophysics Data System (ADS)
Labak, Peter; Lindblom, Pasi; Malich, Gregor
2017-04-01
The Integrated Field Exercise of 2014 (IFE14) was a field event held in the Hashemite Kingdom of Jordan (with concurrent activities in Austria) during which the operational and technical capabilities of a Comprehensive Test Ban Treaty's (CTBT) on-site inspection (OSI) were tested in integrated manner. Many of the inspection techniques permitted by the CTBT were applied during IFE14 including a range of geophysical techniques, however, one of the techniques foreseen by the CTBT but not yet developed is resonance seismometry. During August and September 2016, seismic field measurements have been conducted in the region of Kylylahti, Finland, in support of the further development of geophysical seismic techniques for OSIs. 45 seismic stations were used to continuously acquire seismic signals. During that period, data from local, regional and teleseismic natural events and man-made events were acquired, including from a devastating earthquake in Italy and the nuclear explosion announced by the Democratic People's Republic of Korea on 9 September 2016. Also, data were acquired following the small-scale use of man-made chemical explosives in the area and of vibratory sources. This presentation will show examples from the data set and will discuss its use for the development of resonance seimometry for OSIs.
Experimental Results of Multiple Scattering.
1980-07-01
error is seen to be less for targets with smaller IS()I/IS(O)Iratio like the softer particles made from expanded polystyrene and larger for harder...optical spectrum, we also notice marked differences from the P, Q plots of dylite ( expanded polystyrene ) particles in preceding sections. It was...spheres made of expanded polystyrene . As X is continuously varied for the display of if(e) , we notice a fairly symmetrical intensity profile about X = 8/2
Fusion Reactions and Matter-Antimatter Annihilation for Space Propulsion
2005-07-13
shielding. λ D-3He eliminates the need for a complicated tritium-breeding blanked and tritium-processing system. 4 - MAGNETIC FUSION ENERGY (MFE...resulting specific powers. 5 - INERTIAL FUSION ENERGY (IFE) The possibility of igniting thermonuclear micro-explosions with pulsed laser beams was... fusion energy to antimatter rest mass energy, β, of 1.6 × 107. However, energy utilization is also lower due to the isotropic expansion process (ηe ~ 15
NASA Astrophysics Data System (ADS)
Arndt, R.; Gaya-Pique, L.; Labak, P.; Tanaka, J.
2009-04-01
On-site inspections (OSIs) constitute the final verification measure under the Comprehensive Nuclear-Test-Ban Treaty (CTBT). OSIs are launched to establish whether or not a nuclear explosion has been carried out, thus they are conducted to verify States' compliance with the Treaty. During such an inspection, facts are gathered within a limited investigation area of 1000 Km2 to identify possible violators of the Treaty. Time scale (referring both to the preparation of the inspection as well as to the conduct of an OSI itself) is one of the challenges that an inspection team has to face when conducting an OSI. Other challenges are the size of the team - which is limited to 40 inspectors - and political limitations imposed by the Treaty in the use of allowed techniques. The Integrated Field Exercise 2008 (IFE08) recently conducted in Kazakhstan was the first large-scale, as well as the most comprehensive, on site inspection exercise ever conducted by the Preparatory Commission of the Comprehensive Nuclear-Test-Ban Treaty Organization (CTBTO). The exercise took place in a deserted area south east of Kurchatov, within the former Soviet Union's Semipalatinsk nuclear test site. In this paper we will provide an overview of the technical activities conducted by the inspection team during IFE08 in order to collect evidence for a hypothetical nuclear explosion test. The techniques applied can be distributed in four different blocks: visual observation (to look for man-made changes in the geomorphology as well as anthropogenic features related to an underground nuclear explosion, UNE); passive seismic monitoring (to identify possible aftershocks created by the UNE); radionuclide measurements (to collect evidence for radionuclide isotopes related to a nuclear explosion); and finally geophysical surveys (to identify geophysical signatures related to an UNE in terms of changes in the geological strata, to the hydrogeological regime, and in terms of the shallow remains of the infrastructure deployed during the preparation and monitoring of the test). The data collected during IFE08, together with data from previous exercises, set the fundaments of a database of invaluable value to be used by CTBTO in the future for a better understanding of the phenomenology related to a nuclear explosion.
2000-02-01
HIDS] Program: Power Drive Train Crack Detection Diagnostics and Prognostics ife Usage Monitoring and Damage Tolerance; Techniques, Methodologies, and...and Prognostics , Life Usage Monitoring , and Damage Tolerance; Techniques, Methodologies, and Experiences Andrew Hess Harrison Chin William Hardman...continuing program and deployed engine monitoring systems in fixed to evaluate helicopter diagnostic, prognostic , and wing aircraft, notably on the A
On Learning the Past Tenses of English Verbs.
1985-10-01
RD-AI164 233 ON LEARING THE PAST TENSES OF ENGLISH YERBS(U) vi1 r CALIFORNIA UNIV SAN DIEGO LA JOLLA INST FOR COGNITIVE SCIENCE D E RUMELNART ET AL... COGNITIVE SCIENCE O I$FE13Me~ 0C*" INSTITUTE FOR COGNITIVE SCIENCE UNIVERSITY OF CALIFORNIA, SAN DIEGO LA JOLLA, CALIFORNIA 92093 - *~-’~7...8507 . *** David E. Rurneihart James L. McClelland Institute for Cognitive Science Department of Psychology University of Calif ornia. San Diego
Olowookere, S A; Adegbenro, C A; Idowu, A; Omisore, A G; Shabi, O M; Ikem, U R; Ekwere, G A; Oderinde, I F
2017-01-01
Lassa fever had been reported as a cause of death especially in endemic parts of Nigeria. This study assessed the knowledge, attitude, and practices toward Lassa fever control and prevention among residents of Ile-Ife, southwest Nigeria. Descriptive cross-sectional study was conducted among consenting randomly selected adults using an interviewer administered questionnaire. Data were analyzed using descriptive and inferential statistics. A total of 400 questionnaires with completed data were analyzed (response rate 96%). Majority, 207 (51.8%), were males while 193 (48.2%) were females. Most, 234 (58.5%), had tertiary education while 148 (37%) had secondary education. Fifty-nine percent had heard of Lassa fever with radio as their major source of information. About 76% had inadequate knowledge, 54% had negative attitude while 51% had poor practice toward Lassa fever. Determinants of knowledge of Lassa fever include having higher education (Adjusted Odd Ratio (AOR) = 11.49, 95% CI [3.10, 42.69], p = .0001), being in civil service (AOR = 0.22, 95% CI [0.09, 0.51], p = .01), and earning higher income (AOR = 4.23, 95% CI [2.61, 6.84], p = .0001). In conclusion, the knowledge, attitude, as well as preventive practices to Lassa fever were poor. It is necessary to increase public education and improve hygienic practices.
Declining prevalence of duodenal ulcer at endoscopy in Ile-Ife, Nigeria.
Ijarotimi, O; Soyoye, D O; Adekanle, O; Ndububa, D A; Umoru, B I; Alatise, O I
2017-08-25
Duodenal ulcer is the most common peptic ulcer disease worldwide. In the past, sub-Saharan Africa has been described as an area of mixed prevalence for peptic ulcer disease, but recent reports have disputed this. Changes in the prevalence of duodenal ulcer have been reported, with various reasons given for these. To describe the change in endoscopic prevalence of duodenal ulcer at Obafemi Awolowo University Teaching Hospital (OAUTH), Ile-Ife, Nigeria, between January 2000 and December 2010. This was a retrospective, descriptive study of patients who underwent upper gastrointestinal endoscopy in the endoscopy unit of OAUTH between January 2000 and December 2010. The data were obtained from the endoscopy register, demographic indices, presenting symptoms and post-endoscopic diagnoses being retrieved for each patient. The study period was divided into the years 2000 - 2004 and 2005 - 2010, the frequencies of duodenal ulcer and other post-endoscopic diagnoses being compared between these two time periods to see whether there were changes. Over the study period, 292 patients (15.8%) were diagnosed with duodenal ulcer, second only to 471 patients (26.2%) with acute gastritis. The prevalence of duodenal ulcer for 2000 - 2004 was 22.9% (n=211 patients) compared with 9.2% (n=81) for 2005 - 2010 (p<0.001). There was a significant decline in the endoscopic prevalence of duodenal ulcer over the decade.
Optical wireless networked-systems: applications to aircrafts
NASA Astrophysics Data System (ADS)
Kavehrad, Mohsen; Fadlullah, Jarir
2011-01-01
This paper focuses on leveraging the progress in semiconductor technologies to facilitate production of efficient light-based in-flight entertainment (IFE), distributed sensing, navigation and control systems. We demonstrate the ease of configuring "engineered pipes" using cheap lenses, etc. to achieve simple linear transmission capacity growth. Investigation of energy-efficient, miniaturized transceivers will create a wireless medium, for both inter and intra aircrafts, providing enhanced security, and improved quality-of-service for communications links in greater harmony with onboard systems. The applications will seamlessly inter-connect multiple intelligent devices in a network that is deployable for aircrafts navigation systems, onboard sensors and entertainment data delivery systems, and high-definition audio-visual broadcasting systems. Recent experimental results on a high-capacity infrared (808 nm) system are presented. The light source can be applied in a hybrid package along with a visible lighting LED for both lighting and communications. Also, we present a pragmatic combination of light communications through "Spotlighting" and existing onboard power-lines. It is demonstrated in details that a high-capacity IFE visible light system communicating over existing power-lines (VLC/PLC) may lead to savings in many areas through reduction of size, weight and energy consumption. This paper addresses the challenges of integrating optimized optical devices in the variety of environments described above, and presents mitigation and tailoring approaches for a multi-purpose optical network.
Impairment in face processing in autism spectrum disorder: a developmental perspective.
Greimel, Ellen; Schulte-Rüther, Martin; Kamp-Becker, Inge; Remschmidt, Helmut; Herpertz-Dahlmann, Beate; Konrad, Kerstin
2014-09-01
Findings on face identity and facial emotion recognition in autism spectrum disorder (ASD) are inconclusive. Moreover, little is known about the developmental trajectory of face processing skills in ASD. Taking a developmental perspective, the aim of this study was to extend previous findings on face processing skills in a sample of adolescents and adults with ASD. N = 38 adolescents and adults (13-49 years) with high-functioning ASD and n = 37 typically developing (TD) control subjects matched for age and IQ participated in the study. Moreover, n = 18 TD children between the ages of 8 and 12 were included to address the question whether face processing skills in ASD follow a delayed developmental pattern. Face processing skills were assessed using computerized tasks of face identity recognition (FR) and identification of facial emotions (IFE). ASD subjects showed impaired performance on several parameters of the FR and IFE task compared to TD control adolescents and adults. Whereas TD adolescents and adults outperformed TD children in both tasks, performance in ASD adolescents and adults was similar to the group of TD children. Within the groups of ASD and control adolescents and adults, no age-related changes in performance were found. Our findings corroborate and extend previous studies showing that ASD is characterised by broad impairments in the ability to process faces. These impairments seem to reflect a developmentally delayed pattern that remains stable throughout adolescence and adulthood.
Li, Jin; Lindley-Start, Jack; Porch, Adrian; Barrow, David
2017-07-24
High specification, polymer capsules, to produce inertial fusion energy targets, were continuously fabricated using surfactant-free, inertial centralisation, and ultrafast polymerisation, in a scalable flow reactor. Laser-driven, inertial confinement fusion depends upon the interaction of high-energy lasers and hydrogen isotopes, contained within small, spherical and concentric target shells, causing a nuclear fusion reaction at ~150 M°C. Potentially, targets will be consumed at ~1 M per day per reactor, demanding a 5000x unit cost reduction to ~$0.20, and is a critical, key challenge. Experimentally, double emulsions were used as templates for capsule-shells, and were formed at 20 Hz, on a fluidic chip. Droplets were centralised in a dynamic flow, and their shapes both evaluated, and mathematically modeled, before subsequent shell solidification. The shells were photo-cured individually, on-the-fly, with precisely-actuated, millisecond-length (70 ms), uniform-intensity UV pulses, delivered through eight, radially orchestrated light-pipes. The near 100% yield rate of uniform shells had a minimum 99.0% concentricity and sphericity, and the solidification processing period was significantly reduced, over conventional batch methods. The data suggest the new possibility of a continuous, on-the-fly, IFE target fabrication process, employing sequential processing operations within a continuous enclosed duct system, which may include cryogenic fuel-filling, and shell curing, to produce ready-to-use IFE targets.
Progress in the Science and Technology of Direct Drive Laser Fusion with the KrF Laser
2010-12-01
important parameters KrF technology leads) Direct Laser Drive is a better choice for Energy Indirect Drive (initial path for NIF ) Laser Beams x-rays Hohlraum...Pellet Direct Drive (IFE) Laser Beams Pellet .. • ID Ignition being explored on NIF • Providing high enough gain for pure fusion energy is...challenging. • DD Ignition physics can be explored on NIF . • More efficient use of laser light, and greater flexibility in applying drive provides potential for
Scalloped Hibachi and Vacuum-Pressure Foil for Electra: Electron Beam Pumped KrF Laser
2007-06-01
confinement fusion energy (IFE) applications [1-8]. The foils are a critical part of this durability and efficiency. The electron beam, generated in a high...and A. W. Maschke, “Design descriptions of the Prometheus- L and -H inertial fusion energy drivers,” Fusion Engineering and Design, vol. 25, pp...inertial fusion energy ,” Fusion Engineering and Design, vol. 44, pp. 371-375, March 1999. [4] I. Okuda, e. Takahashi, and Y. Owadano, “A
Electra: Repetitively Pulsed 700 J, 100 ns Electron Beam Pumped KrF Laser
2006-05-01
the Inertial Fusion Energy (IFE) requirements for durability, efficiency, and cost. The technologies developed on Electra should be directly scalable...and S. Searles, "Electron beam pumped krypton fluoride lasers for fusion energy ," Proc. IEEE, vol. 92, pp. 1043-1056, July 2004. [2] M.C. Myers, J.D...34Repetitively pulsed, high energy KrF lasers for inertial fusion energy ," Nucl. Fusion, vol. 44, pp. S247-S253, November 2004. [3] J.D. Sethian, M
Thermal Loading of Thin Metal Foils Used as Electron Beam Windows for a KRF Laser
2005-06-01
the Inertial Fusion Energy (IFE) requirements for durability, efficiency, and cost. One of the challenging laser components is the pressure foil that...R. Welch, D. V. Rose, and S. Searles, "Electron beam pumped krypton fluoride lasers for fusion energy ," Proc. IEEE, vol. 92, pp. 1043-1056, July...D. Weidenheimer, and D. V. Rose, "Repetitively pulsed, high energy KrF lasers for inertial fusion energy ," Nucl. Fusion, vol. 44, pp. S247-S253
Challenges Surrounding the Injection and Arrival of Targets at LIFE Fusion Chamber Center
DOE Office of Scientific and Technical Information (OSTI.GOV)
Miles, R; Spaeth, M; Manes, K
2010-12-01
IFE target designers must consider several engineering requirements in addition to the physics requirements for successful target implosion. These considerations include low target cost, high manufacturing throughput, the ability of the target to survive the injection into the fusion chamber and arrive in a condition and physical position consistent with proper laser-target interaction and ease of post-implosion debris removal. This article briefly describes these considerations for the Laser Inertial Fusion-based Energy (LIFE) targets currently being designed.
Esan, T A; Oziegbe, E O
2015-12-01
The World Health Organization in 1994 recommended that dental education should be problem based, socially and culturally relevant, and community oriented. To explore the perceptions of Pre-phase II (pre-clinical II) dental students on three methods of teaching used during two academic sessions. All part IV dental students in two consecutive sessions undergoing pre phase II course in the Faculty of Dentistry, Obafemi Awolowo University, Ile-Ife were recruited into the study. Three different modes of teaching that is, Problem based learning (PBL), hybrid PBL and traditional teaching were used to teach the students. A twenty two itemed anonymous questionnaire on a five point Likert scale was administered to the students at the end of the course. Six perceived factors were extracted from the questionnaire using factor analysis. There was a statistically significant difference (p < 0.01) between the overall mean of PBL method compared to the other methods of teaching. The perceived factor "communication with peers" had the highest mean score for PBL in both sessions (4.57 ± 0.58 and 4.09 ± 0.93 respectively). However, PBL method was very helpful in all the six perceived factors while the students perceived that the traditional method of teaching was not helpful in "interaction with tutors" and "challenge to critical thinking". The findings showed that students preferred the PBL method to other forms of teaching. PBL enhanced the students' communication skill, was very useful as pedagogic tool and improved their critical thinking.
The Physics of Advanced High-Gain Targets for Inertial Fusion Energy
NASA Astrophysics Data System (ADS)
Perkins, L. John
2010-11-01
In ca. 2011-2012, the National Ignition Facility is poised to demonstrate fusion ignition and gain in the laboratory for the first time. This key milestone in the development of inertial confinement fusion (ICF) can be expected to engender interest in the development of inertial fusion energy (IFE) and expanded efforts on a number of advanced targets that may achieve high fusion energy gain at lower driver energies. In this tutorial talk, we will discuss the physics underlying ICF ignition and thermonuclear burn, examine the requirements for high gain, and outline candidate R&D programs that will be required to assess the performance of these target concepts under various driver systems including lasers, heavy-ions and pulsed power. Such target concepts include those operating by fast ignition, shock ignition, impact ignition, dual-density, magnetically-insulated, one- and two-sided drive, etc., some of which may have potential to burn advanced, non-DT fusion fuels. We will then delineate the role of such targets in their application to the production of high average fusion power. Here, systems studies of IFE economics suggest that we should strive for target fusion gains of around 100 at drive energies of 1MJ, together with corresponding rep-rates of up to 10Hz and driver electrical efficiencies around 15%. In future years, there may be exciting opportunities to study such ``innovative confinement concepts'' with prospects of fielding them on facilities such as NIF to obtain high fusion energy gains on a single shot basis.
Oluwadiya, K S; Olasinde, A A; Olakulehin, O A; Olatoke, S A; Oginni, L M; Ako, F
2007-03-01
Cancellation of cases on the scheduled day of surgery leads to an inefficient utilisation of scarce hospital and patient's resources. Identifying the causes of such cancellations will assist in taking steps to avoid them. This is a retrospective study spanning 10 years. Record was taken of all patients who had orthopaedic surgery at the Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife Nigeria. The age, sex, type of operation, whether or not the surgery was ever postponed or cancelled, the duration and reasons for such postponements and the duration of admission were collated and analysed. Five hundred and fifty two (40.8%) of the 1,353 orthopaedic patients scheduled for surgery experienced cancellation. The most common reasons were attributable to the hospital (48.7%) mainly due to infrastructural breakdown (28.7%) and procedural lapses by hospital personnel (20.0%). Self cancellation by patient (37.8%) followed and was mainly due to financial constraints (25.6%). Upper respiratory tract infections were responsible for the cancellation in 8.6%. These delays were responsible for more than 30% of the duration of admission in 93 (16.8%) patients. The incidence of postponement of cases on the scheduled day of surgery is still high. Most of the causes are preventable. Better infrastructural facilities, enhanced interdepartmental communication and improved attitude to work would reduce the rate and thus enhance utilisation of theatre space.
Tritium Breeding Blanket for a Commercial Fusion Power Plant - A System Engineering Assessment
DOE Office of Scientific and Technical Information (OSTI.GOV)
Meier, Wayne R.
The goal of developing a new source of electric power based on fusion has been pursued for decades. If successful, future fusion power plants will help meet growing world-wide demand for electric power. A key feature and selling point for fusion is that its fuel supply is widely distributed globally and virtually inexhaustible. Current world-wide research on fusion energy is focused on the deuterium-tritium (DT for short) fusion reaction since it will be the easiest to achieve in terms of the conditions (e.g., temperature, density and confinement time of the DT fuel) required to produce net energy. Over the pastmore » decades countless studies have examined various concepts for TBBs for both magnetic fusion energy (MFE) and inertial fusion energy (IFE). At this time, the key organizations involved are government sponsored research organizations world-wide. The near-term focus of the MFE community is on the development of TBB mock-ups to be tested on the ITER tokamak currently under construction in Caderache France. TBB concepts for IFE tend to be different from MFE primarily due to significantly different operating conditions and constraints. This report focuses on longer-term commercial power plants where the key stakeholders include: electric utilities, plant owner and operator, manufacturer, regulators, utility customers, and in-plant subsystems including the heat transfer and conversion systems, fuel processing system, plant safety systems, and the monitoring control systems.« less
Ion distribution in the hot spot of an inertial confinement fusion plasma
NASA Astrophysics Data System (ADS)
Tang, Xianzhu; Guo, Zehua; Berk, Herb
2012-10-01
Maximizing the fusion gain of inertial confinement fusion (ICF) for inertial fusion energy (IFE) applications leads to the standard scenario of central hot spot ignition followed by propagating burn wave through the cold/dense assembled fuel. The fact that the hot spot is surrounded by cold but dense fuel layer introduces subtle plasma physics which requires a kinetic description. Here we perform Fokker-Planck calculations and kinetic PIC simulations for an ICF plasma initially in pressure balance but having large temperature gradient over a narrow transition layer. The loss of the fast ion tail from the hot spot, which is important for fusion reactivity, is quantified by Fokker-Planck models. The role of electron energy transport and the ambipolar electric field is investigated via kinetic simulations and the fluid moment models. The net effect on both hot spot ion temperature and the ion tail distribution, and hence the fusion reactivity, is elucidated.
Multi Jet Induced Forces and Moments on VTOL Aircraft Hovering in and Out of Ground Effect
1977-06-19
It e01 L. h; Lilt’ IFe 1t MI 111)4t , tIpo Ia 1p ra’ue o r 11Iii (’t l I I ’ll I lit V 101 Of it I r, frinm. mit’ kd.own Fot) en us oeu t (I frOe-.1...protX 1111;1 L VIN, M( 0.25. Re fvrenru 5 de ITinus the ecl of ITle roa fcI Low rugilon andic tilL bg n 111lug Of t~he lXIsymmetnriC ca rgi a a11 I’oMtC...impIngement polnt. bC des .! gned as () Thtis dens:1ty Is used to determine NSI in Equation (31). lhe tLotti mass F-.ow il the madi a wo3. ~lcjet in an
de Souza, Fernando Hymnô; Pizzolatti, Bruno Segalla; Schöntag, Juliana Marques; Sens, Maurício Luiz
2016-01-01
Slow sand filters are considered as a great alternative for supplying drinking water in rural and/or isolated areas where raw water that is treatable with this technique is available. Some studies used backwashing as an alternative for cleaning the slow sand filter with the goal of applying the technology in small communities, since filters that supply water to a small number of people do not require much space. In this study the influence of the effective diameter on water quality in the filters and cleaning system was evaluated. A pilot system with six filters was built: three filters were conventionally cleaned by scraping and the other three were cleaned by backwashing, each with a different effective diameter of filter medium. Most filters had an average turbidity of less than 1.0 NTU, the turbidity required at the output of the filters by the Brazilian Ministry of Health Ordinance. In the study, the filters cleaned by scraping with smaller-diameter filter beds effectively filtered water better but had worse effective production. The opposite occurs in the case of backwashed filters.
2001-10-25
stimulation techniques. In contrast to epimesial or intramuscular electrodes, the nerve cuff can be placed proximally on the limb to isolate it from the direct...single cuff can be installed proximally on the limb and control several muscles independently, the amount of surgery required to implant electrodes would... neuroprosthetic system and that would obviate the need for the inclusion of one or more IFEs. V. CONCLUSION Results thus far have shown that the inclusion of a
1969-11-01
Aepetee Alto to Ciae Lake 411 Nthikng slt. Formp 62 Rosts ife Lake 45 LOkt Steno L at 44 14rek.e Lest REPORT FOR P4KLPel KS Tycoee Leka DEVELOPMENT OF...camp sites and group camp use. The Summersville project is located in the Kanawha River Basin, on Gauley River near Summersville in Nicholas County, West...miles of channel snagging and clearing. 11-13-39 The Richwood, West Virginia Project is located on Cherry River in Nicholas County. The project
Lantagne, Daniele; Klarman, Molly; Mayer, Ally; Preston, Kelsey; Napotnik, Julie; Jellison, Kristen
2010-06-01
Diarrhoeal diseases cause an estimated 1.87 million child deaths per year. Point-of-use filtration using locally made ceramic filters improves microbiological quality of stored drinking water and prevents diarrhoeal disease. Scaling-up ceramic filtration is inhibited by lack of universal quality control standards. We investigated filter production variables to determine their affect on microbiological removal during 5-6 weeks of simulated normal use. Decreases in the clay:sawdust ratio and changes in the burnable decreased effectiveness of the filter. Method of silver application and shape of filter did not impact filter effectiveness. A maximum flow rate of 1.7 l(-hr) was established as a potential quality control measure for one particular filter to ensure 99% (2- log(10)) removal of total coliforms. Further research is indicated to determine additional production variables associated with filter effectiveness and develop standardized filter production procedures prior to scaling-up.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Barnard, J. J.; Hay, M. J.; Logan, B. G.
The simulations provided in this milestone have solidified the theoretical underpinning of direct drive targets and also the ability to design experiments on NDCX II that will enhance our understanding of ion-beam hydrodynamic coupling, and thus be relevant to IFE. For the case of the IFE targets, we have studied hydro and implosion efficiency using HYDRA in ID, a starting point towards the goal of polar direct drive in geometry compatible with liquid wall chambers. Recent analysis of direct drive fusion energy targets using heavy ion beams has found high coupling efficiency of ion beam energy into implosion energy. However,more » to obtain optimal coupling, the ion energy must increase during the pulse in order to penetrate the outflowing ablated material, and deposit the energy close enough to the fuel so that the fuel achieves sufficient implosion velocity. We have computationally explored ID (radial) time dependent models of ion driven direct drive capsule implosions using the Arbitrary Lagrangian-Eulerian (ALE) code HYDRA, to help validate the theoretical analysis done so far, particularly exploring the effects of varying the ion energy and ion current over the course of the pulse. On NDCX II, experiments have been proposed to explore issues of ion penetration of the outflowing plasma over the course of the ion pulse. One possibility is to create a first pulse of ions that heats a planar target, and produces an outflow of material. A second pulse, {approx}10 ns after the first, of higher ion energy (and hence larger projected range) will interact with this outflow before reaching and further heating the target. We have investigated whether the change in range can be tailored to match the evolution of the ablation front. We have carried out simulations using the one-dimensional hydrodynamic code DISH and HYDRA to set parameters for this class of experiments. DISH was upgraded with an ion deposition algorithm, and we have carried out ID (planar) simulations. HYDRA was also used for ID (planar) and 2D (r,z) simulations of potential experiments. We have also explored whether similar physics could be studied using an energy ramp (i.e., a velocity tilt) rather than two separate pulses. We have shown that an optimum occurs in the macropulse duration (with fixed velocity tilt) that maximizes the shock strength. In the area of IFE target design we have continued to explore direct drive targets composed of deuterium-tritium fuel and ablator layers. We have extended our previous target designs at 0.44 MJ drive energy, gain 50, (50 MeV foot, 500 MeV main pulse, Rb ion, which requires a large number of beams due to a high beam space charge constraint) to a power plant scale 3.7 MJ drive energy, gain {approx}150 (220 MeV foot, 2.2 GeV main pulse, Hg ion) that eases requirements on the accelerator. We have studied the effects of two important design choices on ICF target performance. We have shown that increasing the number of foot pulses may reduce the target's in-flight adiabat and consequently improve its compressibility and fusion yield. As in the case of laser drive, the first three shocks are the most important to the target's performance, with additional shocks contributing only marginally to compression and burn. We have also demonstrated that ion range lengthening during the main pulse can further reduce the target adiabat and improve the efficiency with which beam energy is coupled into the target. (Ion range lengthening using two different kinetic energies for the foot and main pulse has previously proven effective in the design of high gain targets).« less
Filter replacement lifetime prediction
Hamann, Hendrik F.; Klein, Levente I.; Manzer, Dennis G.; Marianno, Fernando J.
2017-10-25
Methods and systems for predicting a filter lifetime include building a filter effectiveness history based on contaminant sensor information associated with a filter; determining a rate of filter consumption with a processor based on the filter effectiveness history; and determining a remaining filter lifetime based on the determined rate of filter consumption. Methods and systems for increasing filter economy include measuring contaminants in an internal and an external environment; determining a cost of a corrosion rate increase if unfiltered external air intake is increased for cooling; determining a cost of increased air pressure to filter external air; and if the cost of filtering external air exceeds the cost of the corrosion rate increase, increasing an intake of unfiltered external air.
Oguntoye, Oluwatosin O; Ndububa, Dennis A; Yusuf, Musah; Bolarinwa, Rahman A; Ayoola, Oluwagbemiga O
2017-01-01
Sickle cell anaemia (SCA) is associated with structural manifestations in the hepatobiliary axis. This study aimed to investigate the hepatobiliary ultrasonographic abnormalities in adult patients with sickle cell anaemia in steady state attending the Haematology clinic of a federal tertiary health institution in Ile-Ife, Nigeria. Basic demographic data as well as right upper abdominal quadrant ultrasonography of 50 consecutive sickle cell anaemia patients were compared with those of 50 age- and sex-matched subjects with HbAA as controls. Each of the study groups (patients and controls) comprised of 21 (42%) males and 29 (58%) females. The age range of the patients was 18-45 years with a mean (±SD) of 27.6±7.607 years, while that of the controls was 21-43 years with a mean (±SD) of 28.0±5.079 years (p=0.746). Amongst the patients, 32 (64%) had hepatomegaly, 15 (30%) cholelithiasis and 3 (6%) biliary sludge. Fourteen (28%) of the patients had normal hepatobiliary ultrasound findings. In the control group, one (2%) person had cholelithiasis, one (2%) biliary sludge, one (2%) fatty liver and none hepatomegaly. Forty-seven (94%) of the controls had normal hepatobiliary ultrasound findings. There was a statistically significant difference in the prevalence of hepatomegaly and cholelithiasis between the patients and controls (p value <0.001 for both comparisons). In this study, hepatomegaly, cholelithiasis and biliary sludge were the most common hepatobiliary ultrasound findings in patients with sickle cell anaemia. Ultrasonography is a useful tool for assessing hepatobiliary abnormalities in patients with sickle cell anaemia.
Ola, Dennis; Gambôa, Ana B O; Folayan, Morenike O; Marcenes, Wagner
2013-01-01
To test the relationship between socioeconomic position (SEP), family composition, number of siblings, and birth position in the family, and the utilization of oral health services by senior secondary school pupils in Ile-Ife, Nigeria. A cross-sectional study design included senior secondary school pupils in the Central Local Government Area of Ile-Ife during 2007/2008. Sample size calculation was performed and 1,200 pupils were invited to participate. A multistage, stratified sampling technique was used. Data collection included a self-administered questionnaire. Data were analyzed using logistic regression. The response rate was 76 percent (n=1043). The mean age was 15.8 (standard deviation=1.9) and 49 percent were males. Only 22.5 percent of pupils had ever visited a dentist in their lives. Results from multivariate analyses showed that pupils attending free schools, those paying 1 to 10,000 naira (equivalent to US$ 63.31) and 10,000 to 19,000 naira (equivalent to US$ 120.29) were respectively 1.93, 1.87, and 2.74 times less likely to have attended a dentist in the past than pupils in more expensive schools. Pupils living with single mothers or without a parent were unlikely to have visited the dentist. Number of siblings and birth position in the family were not associated with utilization of oral health services. Adolescents from families with a low SEP growing up without their parents may need extra incentives to visit dentist. © 2012 American Association of Public Health Dentistry.
Some socio-cultural factors influencing fertility behaviour: a case study of Yoruba women.
Akande, B
1989-12-01
The sociocultural factors impacting on fertility behavior among the Yoruba of Nigeria were investigated in a sample of 330 women, 199 from Ife-Ife urban area and 131 from 3 rural villages also in the Oranmiyan Local Government Area. All study participants were Yoruba women married to Yoruba men who had at least 1 child; their mean age was 34.5 years and 41% had no education. The study was conducted during 1987. The responses confirmed the close link between marriage and procreation in this culture. Children are valued as a source of prestige to a woman, and childless women are stigmatized. The reasons for which children are valued were found to vary according to educational level. 77% of women with no education compared with 41% of those with high levels of education value children as a source of caretaking in old age. In contrast, 44% of highly educated women versus 11% of uneducated women valued children as a source of joy. Educated women were also more likely than women with no education to view motherhood as a means of fulfilling God's command to continue the human race. In terms of sex preference, higher percentages of educated and urban women wanted their 1st child to be a male and son preference has strong religious, legal, and social status significance in the Yoruban culture. However, all respondents indicated they wanted to have children of both sexes. More information on sociocultural factors examined in this study is needed to help in the design of a population policy for the Yoruba.
EFFECT OF LOADING DUST TYPE ON THE FILTRATION EFFICIENCY OF ELECTROSTATICALLY CHARGED FILTERS
The paper gives results of an evaluation of the effect of loading dust type on the filtration efficiency of electrostatically charged filters. Three types of filters were evaluated: a rigid-cell filter charged using an electrodynamic spinning process, a pleated-panel filter cha...
Long-Term Safety and Effectiveness of the 'OptEase' Vena Cava Filter
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kalva, Sanjeeva P., E-mail: skalva@partners.org; Marentis, Theodore C.; Yeddula, Kalpana
Purpose: To assess the long-term safety and effectiveness of the OptEase inferior vena cava (IVC) filter. Materials and Methods: In this Institutional Review Board-approved, retrospective study, we reviewed data of 71 patients who received an OptEase filter at our institution from 2002 to 2007. Thirty-nine (55%) patients had symptoms of venous thromboembolism before filter placement. The indications for filter included contraindication to anticoagulation in 31 (44%) patients, prophylaxis against pulmonary embolism (PE) in 29 (41%) patients, and failure of anticoagulation in 11 (15%) patients. Procedure-related complications, such as symptomatic post-filter PE, deep venous thrombosis (DVT), IVC occlusion, and incidental imaging-evidentmore » filter-related complications, were recorded. Safety was assessed by the occurrence of filter-related complications during placement and follow-up. Effectiveness was assessed by the occurrence of post-filter PE. Results: Sixty-five (92%) filters were placed under fluoroscopy, and 6 (8%) were placed using intravascular ultrasound guidance. Seventy (99%) filters were placed successfully. Seven (10%) filters were placed in the suprarenal cava. Retrieval was attempted in 14 (20%) patients, and 12 filters were successfully retrieved. Clinical follow-up was available for 20 {+-} 21 months. Symptoms of postfilter PE and DVT occurred in 15% (n = 11) and 10% (n = 7) patients, respectively. None of these patients had computed tomography (CT)-proven PE, and only one had ultrasound-proven new DVT. One patient had symptomatic IVC occlusion. Follow-up abdominal CT in 20 patients showed thrombus in the filter in two of them. There were no instances of filter migration, filter tilt, or caval wall penetration. Conclusion: The OptEase filter appears to have an acceptable long-term safety profile. The filter was effective against PE.« less
Preliminary analysis on the water quality index (WQI) of irradiated basic filter elements
NASA Astrophysics Data System (ADS)
Arif Abu Bakar, Asyraf; Muhamad Pauzi, Anas; Aziz Mohamed, Abdul; Syima Sharifuddin, Syazrin; Mohamad Idris, Faridah
2018-01-01
Simple water filtration system is needed in times of extreme floods. Clean water for sanitation at evacuation centres is essential and its production is possible by using the famous simple filtration system consisting of empty bottle and filter elements (sands, gravels, cotton/coffee filter). This research intends to study the effects of irradiated filter elements on the filtration effectiveness through experiments. The filter elements will be irradiated with gamma and neutron radiation using the facilities available at Malaysia Nuclear Agency. The filtration effectiveness is measured using the water quality index (WQI) that is developed in this study to reflect the quality of filtered water. The WQI of the filtered water using the system with irradiated filter elements is then compared with that of the system with non-irradiated filter elements. This preliminary analysis only focus on filtration element of silica sand. Results shows very nominal variation in in WQI after filtered by non-irradiated, gamma and neutron filter element (silica sand), where the hypothesis could not be affirmed.
Rudell, B.; Wass, U.; Horstedt, P.; Levin, J. O.; Lindahl, R.; Rannug, U.; Sunesson, A. L.; Ostberg, Y.; Sandstrom, T.
1999-01-01
OBJECTIVES: To evaluate the efficiency of different automotive cabin air filters to prevent penetration of components of diesel exhaust and thereby reduce biomedical effects in human subjects. Filtered air and unfiltered diluted diesel exhaust (DDE) were used as negative and positive controls, respectively, and were compared with exposure to DDE filtered with four different filter systems. METHODS: 32 Healthy non- smoking subjects (age 21-53) participated in the study. Each subject was exposed six times for 1 hour in a specially designed exposure chamber: once to air, once to unfiltered DDE, and once to DDE filtered with the four different cabin air filters. Particle concentrations during exposure to unfiltered DDE were kept at 300 micrograms/m3. Two of the filters were particle filters. The other two were particle filters combined with active charcoal filters that might reduce certain gaseous components. Subjective symptoms were recorded and nasal airway lavage (NAL), acoustic rhinometry, and lung function measurements were performed. RESULTS: The two particle filters decreased the concentrations of diesel exhaust particles by about half, but did not reduce the intensity of symptoms induced by exhaust. The combination of active charcoal filters and a particle filter significantly reduced the symptoms and discomfort caused by the diesel exhaust. The most noticable differences in efficacy between the filters were found in the reduction of detection of an unpleasant smell from the diesel exhaust. In this respect even the two charcoal filter combinations differed significantly. The efficacy to reduce symptoms may depend on the abilities of the filters investigated to reduce certain hydrocarbons. No acute effects on NAL, rhinometry, and lung function variables were found. CONCLUSIONS: This study has shown that the use of active charcoal filters, and a particle filter, clearly reduced the intensity of symptoms induced by diesel exhaust. Complementary studies on vehicle cabin air filters may result in further diminishing the biomedical effects of diesel exhaust in subjects exposed in traffic and workplaces. PMID:10450238
Low frequency wave propagation in a cold magnetized dusty plasma
NASA Astrophysics Data System (ADS)
Sarkar, S.; Ghosh, S.; Khan, M.
1998-12-01
In this paper several characteristics of low frequency waves in a cold magnetized dusty plasma propagating parallel and perpendicular to the static background magnetic field have been investigated. In the case of parallel propagation the negatively charged dust particles resonate with the right circularly polarized (RCP) component of em waves when the wave frequency equals the dust cyclotron frequency. It has been shown that an RCP wave in dusty plasma consists of two branches and there exists a region where an RCP wave propagation is not possible. Dispersion relation, phase velocity and group velocity of RCP waves have been obtained and propagation characteristics have been shown graphically. Poynting flux and Faraday rotation angles have been calculated for both lower and upper branches of the RCP wave. It has been observed that sense of rotation of the plane of polarization of the RCP wave corresponding to two distinct branches are opposite. Finally, the effect of dust particles on the induced magnetization from the inverse Faraday effect (IFE) due to the interaction of low frequency propagating and standing em waves with dusty plasmas has been evaluated.
Does partial occlusion promote normal binocular function?
Li, Jingrong; Thompson, Benjamin; Ding, Zhaofeng; Chan, Lily Y L; Chen, Xiang; Yu, Minbin; Deng, Daming; Hess, Robert F
2012-10-03
There is growing evidence that abnormal binocular interactions play a key role in the amblyopia syndrome and represent a viable target for treatment interventions. In this context the use of partial occlusion using optical devices such as Bangerter filters as an alternative to complete occlusion is of particular interest. The aims of this study were to understand why Bangerter filters do not result in improved binocular outcomes compared to complete occlusion, and to compare the effects of Bangerter filters, optical blur and neutral density (ND) filters on normal binocular function. The effects of four strengths of Bangerter filters (0.8, 0.6, 0.4, 0.2) on letter and vernier acuity, contrast sensitivity, stereoacuity, and interocular suppression were measured in 21 observers with normal vision. In a subset of 14 observers, the partial occlusion effects of Bangerter filters, ND filters and plus lenses on stereopsis and interocular suppression were compared. Bangerter filters did not have graded effect on vision and induced significant disruption to binocular function. This disruption was greater than that of monocular defocus but weaker than that of ND filters. The effect of the Bangerter filters on stereopsis was more pronounced than their effect on monocular acuity, and the induced monocular acuity deficits did not predict the induced deficits in stereopsis. Bangerter filters appear to be particularly disruptive to binocular function. Other interventions, such as optical defocus and those employing computer generated dichoptic stimulus presentation, may be more appropriate than partial occlusion for targeting binocular function during amblyopia treatment.
Mechanisms Involved in Immunity to Malarial Parasites.
1980-07-01
FIG 6/5 NI momIIIIoIIII IEEEEEEEEIIIEE EE EE EE 1 . It.; .9 21 l....- 1.. _.__ - . 1.251 1.61 MICROCOPY RESOLUTION TEST CHART NATIONAL euREAu OF...OISTIMMUTIONSTATEIMENT (.4.O wM ~dJlIfeIn 10* It. iv dO d *Wf ReeIM0 14. SUPPS.EEmXTAAV MOTES SL AMWMAC? I ~ ~ -U ~ 1rb .O~ * ~ 13 S S P GIN sle as GS.SI...adequate controls in testing , ihumayt imne sora for ant4p=6asitic act:iviLt7. Intacted blood. from 82 patient. was oryopreserved. Thirty-f our Pat
Habitat Suitability Index Models: Mottled duck
Rorabaugh, James C.; Zwank, Phillip J.
1983-01-01
The mottled duck is a mallard-like resident species of the Gulf of Mexico coast, from the marshes of Pearl River on the Lou i si ana-Ht ss t ss ipp i border to the Al varado Lagoon near Veracruz, Mexico (Bell rose 1976). The highest densities of nesting mottl ed ducks are found in brackish to fresh coastal marshes (H. Bateman, Louisiana Department of Wildl ife and Fisheries, Baton Rouge; pers , comm.). Mottled ducks also inhabit prairie land near prairie potholes in Texas and flooded rice fields in Texas (Engel ing 1950) and Louisiana (Linscombe 1972).
HEDP and new directions for fusion energy
NASA Astrophysics Data System (ADS)
Kirkpatrick, Ronald C.
2010-06-01
Magnetic-confinement fusion energy and inertia-confinement fusion energy (IFE) represent two extreme approaches to the quest for the application of thermonuclear fusion to electrical energy generation. Blind pursuit of these extreme approaches has long delayed the achievement of their common goal. We point out the possibility of an intermediate approach that promises cheaper, and consequently more rapid development of fusion energy. For example, magneto-inertial fusion appears to be possible over a broad range of parameter space. It is further argued that imposition of artificial constraints impedes the discovery of physics solutions for the fusion energy problem.
New amplifying laser concept for inertial fusion driver
NASA Astrophysics Data System (ADS)
Mourou, G. A.; Labaune, C.; Hulin, D.; Galvanauskas, A.
2008-05-01
This paper presents a new amplifying laser concept designed to produce high energy in either short or long pulses using coherent or incoherent addition of few millions fibers. These are called respectively CAN for Coherent Amplification Network and FAN for Fiber Amplification Network. The fibers would be large core or Large Mode Area (LMA) which have demonstrated up to 10, mJ output energy per fiber1. Such a system could meet the driver criteria of Inertial Fusion Energy (IFE) power plants based on Inertial Confinement Fusion (ICF), in particular high efficiency and high repetition rate.
Mothers' concept of measles and attitudes towards the measles vaccine in Ile-Ife, Nigeria.
Odebiyi, A I; Ekong, S C
1982-09-01
The attitude of Nigerian mothers, mainly Yoruba, towards measles vaccine and other aspects of prevention are influenced by different perceptions of the cause of measles. There is a significant correlation between the literacy of mothers and their belief in the efficacy of measles vaccine but not between their ages and belief. The mothers' perception of measles is a function of their socioeconomic characteristics, with the lower socioeconomic group tending more to define measles within the supernatural context. The findings indicate the necessity for health education to be based on local culture when promoting vaccination.
A Study Into the Effects of Kalman Filtered Noise in Advanced Guidance Laws of Missile Navigation
2014-03-01
Kalman filtering algorithm is a highly effective linear state estimator . Known as the workhorse of estimation , the discrete time Kalman filter uses ...15]. At any discrete time 1k the state estimate can be determined by (3.7). A Kalman filter estimates the state using the process described in...acceleration is calculated using Kalman filter outputs. It is not available to the Kalman filter for
Virtual experiment of optical spatial filtering in Matlab environment
NASA Astrophysics Data System (ADS)
Ji, Yunjing; Wang, Chunyong; Song, Yang; Lai, Jiancheng; Wang, Qinghua; Qi, Jing; Shen, Zhonghua
2017-08-01
The principle of spatial filtering experiment has been introduced, and the computer simulation platform with graphical user interface (GUI) has been made out in Matlab environment. Using it various filtering processes for different input image or different filtering purpose will be completed accurately, and filtering effect can be observed clearly with adjusting experimental parameters. The physical nature of the optical spatial filtering can be showed vividly, and so experimental teaching effect will be promoted.
Infrared image background modeling based on improved Susan filtering
NASA Astrophysics Data System (ADS)
Yuehua, Xia
2018-02-01
When SUSAN filter is used to model the infrared image, the Gaussian filter lacks the ability of direction filtering. After filtering, the edge information of the image cannot be preserved well, so that there are a lot of edge singular points in the difference graph, increase the difficulties of target detection. To solve the above problems, the anisotropy algorithm is introduced in this paper, and the anisotropic Gauss filter is used instead of the Gauss filter in the SUSAN filter operator. Firstly, using anisotropic gradient operator to calculate a point of image's horizontal and vertical gradient, to determine the long axis direction of the filter; Secondly, use the local area of the point and the neighborhood smoothness to calculate the filter length and short axis variance; And then calculate the first-order norm of the difference between the local area of the point's gray-scale and mean, to determine the threshold of the SUSAN filter; Finally, the built SUSAN filter is used to convolution the image to obtain the background image, at the same time, the difference between the background image and the original image is obtained. The experimental results show that the background modeling effect of infrared image is evaluated by Mean Squared Error (MSE), Structural Similarity (SSIM) and local Signal-to-noise Ratio Gain (GSNR). Compared with the traditional filtering algorithm, the improved SUSAN filter has achieved better background modeling effect, which can effectively preserve the edge information in the image, and the dim small target is effectively enhanced in the difference graph, which greatly reduces the false alarm rate of the image.
NASA Astrophysics Data System (ADS)
Puttisong, Y.; Wang, X. J.; Buyanova, I. A.; Chen, W. M.
2013-03-01
The effect of hyperfine interaction (HFI) on the recently discovered room-temperature defect-enabled spin-filtering effect in GaNAs alloys is investigated both experimentally and theoretically based on a spin Hamiltonian analysis. We provide direct experimental evidence that the HFI between the electron and nuclear spin of the central Ga atom of the spin-filtering defect, namely, the Gai interstitials, causes strong mixing of the electron spin states of the defect, thereby degrading the efficiency of the spin-filtering effect. We also show that the HFI-induced spin mixing can be suppressed by an application of a longitudinal magnetic field such that the electronic Zeeman interaction overcomes the HFI, leading to well-defined electron spin states beneficial to the spin-filtering effect. The results provide a guideline for further optimization of the defect-engineered spin-filtering effect.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gill, K; Aldoohan, S; Collier, J
Purpose: Study image optimization and radiation dose reduction in pediatric shunt CT scanning protocol through the use of different beam-hardening filters Methods: A 64-slice CT scanner at OU Childrens Hospital has been used to evaluate CT image contrast-to-noise ratio (CNR) and measure effective-doses based on the concept of CT dose index (CTDIvol) using the pediatric head shunt scanning protocol. The routine axial pediatric head shunt scanning protocol that has been optimized for the intrinsic x-ray tube filter has been used to evaluate CNR by acquiring images using the ACR approved CT-phantom and radiation dose CTphantom, which was used to measuremore » CTDIvol. These results were set as reference points to study and evaluate the effects of adding different filtering materials (i.e. Tungsten, Tantalum, Titanium, Nickel and Copper filters) to the existing filter on image quality and radiation dose. To ensure optimal image quality, the scanner routine air calibration was run for each added filter. The image CNR was evaluated for different kVps and wide range of mAs values using above mentioned beam-hardening filters. These scanning protocols were run under axial as well as under helical techniques. The CTDIvol and the effective-dose were measured and calculated for all scanning protocols and added filtration, including the intrinsic x-ray tube filter. Results: Beam-hardening filter shapes energy spectrum, which reduces the dose by 27%. No noticeable changes in image low contrast detectability Conclusion: Effective-dose is very much dependent on the CTDIVol, which is further very much dependent on beam-hardening filters. Substantial reduction in effective-dose is realized using beam-hardening filters as compare to the intrinsic filter. This phantom study showed that significant radiation dose reduction could be achieved in CT pediatric shunt scanning protocols without compromising in diagnostic value of image quality.« less
Kolawole, Kikelomo Adebanke; Folayan, Morenike Oluwatoyin; Agbaje, Hakeem Olatunde; Oyedele, Titus Ayodeji; Oziegbe, Elizabeth Obhioneh; Onyejaka, Nneka Kate; Chukwumah, Nneka Maureen; Oshomoji, Olusegun Victor
2016-01-01
Objectives Non-nutritive sucking (NNS) is a common behavior in childhood. The association between digit sucking, dental caries and oral health has been studied with inconclusive results. The objectives of this study were to determine the prevalence of, and the association between digit sucking, caries and oral hygiene status of children age six months to 12 years, resident in Ile-Ife, Osun State, Nigeria. Methods A cross-sectional study was conducted in Ife Central Local Government Area of Osun State. Data were collected through a household survey using a multi-stage sampling procedure from children between six months and 12 years. Details of each child’s socio-demographic characteristics, digit sucking habits, caries status and oral health status were collected. The association between digit sucking, caries status and oral hygiene status was determined using Chi square and Logistic regression. Results The mean age of the 992 study participants was 5.8 ± (3.2) years. The prevalence of digit sucking, caries and poor oral hygiene were 7.2%, 10.5% and 2.4% respectively. The mean dmft score was 0.22 ± (0.80), mean DMFT score was 0.04 ± (0.30) while mean Oral Hygiene Index score was 1.27 ± (0.73). Digit sucking increased the odds of having caries (OR: 1.28; CI: 0.58–2.81) but decreased the odds of having poor oral hygiene (OR: 0.58; CI: 0.34–1.01) insignificantly. Conclusions Digit sucking was not a significant predictor of caries and oral hygiene status, although the odds of having caries increased while the odds of having poor oral hygiene decreased with digit sucking. PMID:26890262
Anyabolu, Henry Chineme; Adejuyigbe, Ebunoluwa Aderonke; Adeodu, Oluwagbemiga Oyewole
2014-01-01
Case control studies that assess the burden and factors associated with undernutrition and anaemia among HAART naïve HIV infected children in Nigeria is very sparse. This will help to formulate nutritional programs among these children. Seventy HAART naive HIV infected children aged 18 months and above were as well as seventy age and sex matched HIV negative children were recruited from August 2007 to January 2009 at Paediatric Clinic of Obafemi Awolowo University Teaching Hospital Complex, Ile-Ife, Nigeria. Their bio data, WHO clinical stage, anthropometric measurements, haematocrit, serum albumin and CD4 counts were taken with other parameters according to a study proforma. The prevalence of stunting, underweight and wasting among the HIV infected subjects were 48. 6%,58. 6% and 31. 4% respectively which as significantly higher than 28. 1%, 7. 1% and 28. 1% among the HIV negative controls. 20. 1% of the HIV infected children were marasmic compared to 2. 3% of the controls. Triple anthropometric failure was found in 7. 1% of the subjects as compared to none among the controls. Anaemia is significantly more prevalent among the subjects than the controls (70. 0% vs 31. 4%; p<0. 001). The prevalence of anaemia was higher in the HIV infected subjects with undernutrition. Low socioeconomic status, hypoalbuminemia and severe immunosuppression are significantly associated with higher undernutrition prevalence. Several years after availability of HAART, undernutrition and anaemia remain widely prevalent among newly presenting HAART naïve HIV infected Nigerian children. Nutritional supplementation and evaluation for anaemia still need close attention in the management of these children.
Igbeneghu, Oluwatoyin A; Lamikanra, Adebayo
2014-11-28
The upsurge in the demand for bottled water has prompted the interest of many manufacturers in the production of bottled water and very many water bottling companies are therefore involved in its production. These range from large scale multinational companies to medium scale business enterprises, institutional and government business investment companies as well as small scale entrepreneurs. There is however little information on the comparative quality of bottled water brands produced by different classes of water bottling companies in Nigeria. This study was undertaken to determine the bacteriological quality of brands of bottled water available to consumers in Ile-Ife. Forty-three samples of bottled water comprising of three batches each of thirteen bottled water brands and two batches of two brands were purchased and analyzed for total bacterial count, presence of coliform and the presence of other bacterial indicators of drinking water quality. Only 67.4% of the water samples representing the products of 10 companies or 66.7% of the brands had heterotrophic counts within the acceptable limits. Coliforms present in 100 ml of water were detected in 26.7% of the bottled water brands. Other indicator organisms detected included Staphylococci isolated from 27.9% of the samples (33.3% of the brands) and specifically Staphylococcus aureus found in four brands constituting 14% of the samples. Pseudomonas strains were consistently detected in consecutive batches of three brands of the water samples. Bottled water samples produced by the large scale multinational producers were of acceptable bacteriological quality unlike those produced by most small companies. There is need for a greater control of water bottling processes carried out by commercial bottled water producers in Nigeria.
Temilola, Dada Oluwaseyi; Folayan, Morenike Oluwatoyin; Fatusi, Olawunmi; Chukwumah, Nneka Maureen; Onyejaka, Nneka; Oziegbe, Elizabeth; Oyedele, Titus; Kolawole, Kikelomo Adebanke; Agbaje, Hakeem
2014-10-16
The study of dental anomalies is important because it generates information that is important for both the anthropological and clinical management of patients. The objective of this study is to determine the prevalence and pattern of presentation of dental hard-tissue developmental anomalies in the mix dentition of children residing in Ile-Ife, a suburban region of Nigeria. Information on age, sex and socioeconomic status was collected from 1,036 children aged four months to 12 years through a household survey. Clinical examination was conducted to assess the presence of dental anomalies. Associations between age, sex, socioeconomic status, prevalence, and pattern of presentation of the developmental hard-tissue dental anomalies were determined. Two hundred and seventy six (26.6%) children had dental anomalies. Of these, 23.8% had one anomaly, 2.5% had two anomalies, and 0.3% had more than two anomalies. Of the children with anomalies, 49.3%were male, 50.7%were female, and 47.8%, 28.6% and 23.6% were children from low, middle and high socioeconomic classes, respectively. More anomalies were seen in permanent than primary dentition. Anomalies of tooth structure were most prevalent (16.1%); anomalies which affect tooth number were least prevalent (1.3%). Dens evaginatus, peg-shaped lateral, macrodontia, and talon cusp were more prevalent in the permanent dentition, and dens evaginatus peg-shaped lateral and macrodontia were more prevalent in the maxilla. There were significantly more macrodontia anomalies in males and in children of high socioeconomic status. This large survey of dental hard-tissue anomalies found in the primary dentition and mixed dentition of children in Nigeria provides anthropological and clinical data that may aid the detection and management of dental problems of children in Nigeria.
Oguntoye, Oluwatosin O.; Ndububa, Dennis A.; Yusuf, Musah; Bolarinwa, Rahman A.; Ayoola, Oluwagbemiga O.
2017-01-01
Summary Background Sickle cell anaemia (SCA) is associated with structural manifestations in the hepatobiliary axis. This study aimed to investigate the hepatobiliary ultrasonographic abnormalities in adult patients with sickle cell anaemia in steady state attending the Haematology clinic of a federal tertiary health institution in Ile-Ife, Nigeria. Material/Methods Basic demographic data as well as right upper abdominal quadrant ultrasonography of 50 consecutive sickle cell anaemia patients were compared with those of 50 age- and sex-matched subjects with HbAA as controls. Results Each of the study groups (patients and controls) comprised of 21 (42%) males and 29 (58%) females. The age range of the patients was 18–45 years with a mean (±SD) of 27.6±7.607 years, while that of the controls was 21–43 years with a mean (±SD) of 28.0±5.079 years (p=0.746). Amongst the patients, 32 (64%) had hepatomegaly, 15 (30%) cholelithiasis and 3 (6%) biliary sludge. Fourteen (28%) of the patients had normal hepatobiliary ultrasound findings. In the control group, one (2%) person had cholelithiasis, one (2%) biliary sludge, one (2%) fatty liver and none hepatomegaly. Forty-seven (94%) of the controls had normal hepatobiliary ultrasound findings. There was a statistically significant difference in the prevalence of hepatomegaly and cholelithiasis between the patients and controls (p value <0.001 for both comparisons). Conclusions In this study, hepatomegaly, cholelithiasis and biliary sludge were the most common hepatobiliary ultrasound findings in patients with sickle cell anaemia. Ultrasonography is a useful tool for assessing hepatobiliary abnormalities in patients with sickle cell anaemia. PMID:28105246
Real-time 3D radiation risk assessment supporting simulation of work in nuclear environments.
Szőke, I; Louka, M N; Bryntesen, T R; Bratteli, J; Edvardsen, S T; RøEitrheim, K K; Bodor, K
2014-06-01
This paper describes the latest developments at the Institute for Energy Technology (IFE) in Norway, in the field of real-time 3D (three-dimensional) radiation risk assessment for the support of work simulation in nuclear environments. 3D computer simulation can greatly facilitate efficient work planning, briefing, and training of workers. It can also support communication within and between work teams, and with advisors, regulators, the media and public, at all the stages of a nuclear installation's lifecycle. Furthermore, it is also a beneficial tool for reviewing current work practices in order to identify possible gaps in procedures, as well as to support the updating of international recommendations, dissemination of experience, and education of the current and future generation of workers.IFE has been involved in research and development into the application of 3D computer simulation and virtual reality (VR) technology to support work in radiological environments in the nuclear sector since the mid 1990s. During this process, two significant software tools have been developed, the VRdose system and the Halden Planner, and a number of publications have been produced to contribute to improving the safety culture in the nuclear industry.This paper describes the radiation risk assessment techniques applied in earlier versions of the VRdose system and the Halden Planner, for visualising radiation fields and calculating dose, and presents new developments towards implementing a flexible and up-to-date dosimetric package in these 3D software tools, based on new developments in the field of radiation protection. The latest versions of these 3D tools are capable of more accurate risk estimation, permit more flexibility via a range of user choices, and are applicable to a wider range of irradiation situations than their predecessors.
Kolawole, Kikelomo Adebanke; Folayan, Morenike Oluwatoyin; Agbaje, Hakeem Olatunde; Oyedele, Titus Ayodeji; Oziegbe, Elizabeth Obhioneh; Onyejaka, Nneka Kate; Chukwumah, Nneka Maureen; Oshomoji, Olusegun Victor
2016-01-01
Non-nutritive sucking (NNS) is a common behavior in childhood. The association between digit sucking, dental caries and oral health has been studied with inconclusive results. The objectives of this study were to determine the prevalence of, and the association between digit sucking, caries and oral hygiene status of children age six months to 12 years, resident in Ile-Ife, Osun State, Nigeria. A cross-sectional study was conducted in Ife Central Local Government Area of Osun State. Data were collected through a household survey using a multi-stage sampling procedure from children between six months and 12 years. Details of each child's socio-demographic characteristics, digit sucking habits, caries status and oral health status were collected. The association between digit sucking, caries status and oral hygiene status was determined using Chi square and Logistic regression. The mean age of the 992 study participants was 5.8 ± (3.2) years. The prevalence of digit sucking, caries and poor oral hygiene were 7.2%, 10.5% and 2.4% respectively. The mean dmft score was 0.22 ± (0.80), mean DMFT score was 0.04 ± (0.30) while mean Oral Hygiene Index score was 1.27 ± (0.73). Digit sucking increased the odds of having caries (OR: 1.28; CI: 0.58-2.81) but decreased the odds of having poor oral hygiene (OR: 0.58; CI: 0.34-1.01) insignificantly. Digit sucking was not a significant predictor of caries and oral hygiene status, although the odds of having caries increased while the odds of having poor oral hygiene decreased with digit sucking.
Esan, O; Ikem, I C; Orimolade, E A; Esan, O T
2014-06-01
This included determining aetiology of failure and comparing the failure rate in implant fixations using solid intramedullary nail and DCP. A retrospective study conducted at the Orthopaedic Department, Obafemi Awolowo University Teaching Hospital, Ile-Ife,Nigeria. Records of all operated cases of lower limb long bone diaphyseal fractures including those with failed fixations from August 2006-July 2011 were reviewed. Data retrieved included type of implant used, aetiology and characteristics of Implant failure. Data were analysed using SPSS version 16. Frequency distribution of the variables of interest was done. Difference in failure rate of intramedullary nail versus DCP was tested using chi-square. Statistical significance was inferred at p<0.05. A total of 280 patients were studied out of which two hundred and twenty-one patients had long bone diaphyseal fractures and met inclusion criteria, of which 135 had intramedullary nail fixation and 86 had DCP. The rate of implant failure in intramedullary nail was 1.5% while it was 5.8% in patients with DCP (p=0.113; 0R=4.10; 95% CI=0.65- 43.77). Implant fracture was the commonest type of failure seen (100% versus 60%) and non union was the commonest cause of failure seen (50% versus 40%) in the intramedullary nailing and DCP groups respectively. The likelihood of a failed implant is higher in fixations done with DCP compared with intramedullary nail though the difference was not statistically significant. Commonest reason for failure in both groups was non-union. Findings from this study may guide surgeons in choice of implant in the management of long bone fractures.
Effectiveness of adverse effects search filters: drugs versus medical devices.
Farrah, Kelly; Mierzwinski-Urban, Monika; Cimon, Karen
2016-07-01
The study tested the performance of adverse effects search filters when searching for safety information on medical devices, procedures, and diagnostic tests in MEDLINE and Embase. The sensitivity of 3 filters was determined using a sample of 631 references from 131 rapid reviews related to the safety of health technologies. The references were divided into 2 sets by type of intervention: drugs and nondrug health technologies. Keyword and indexing analysis were performed on references from the nondrug testing set that 1 or more of the filters did not retrieve. For all 3 filters, sensitivity was lower for nondrug health technologies (ranging from 53%-87%) than for drugs (88%-93%) in both databases. When tested on the nondrug health technologies set, sensitivity was lower in Embase (ranging from 53%-81%) than in MEDLINE (67%-87%) for all filters. Of the nondrug records that 1 or more of the filters missed, 39% of the missed MEDLINE records and 18% of the missed Embase records did not contain any indexing terms related to adverse events. Analyzing the titles and abstracts of nondrug records that were missed by any 1 filter, the most commonly used keywords related to adverse effects were: risk, complications, mortality, contamination, hemorrhage, and failure. In this study, adverse effects filters were less effective at finding information about the safety of medical devices, procedures, and tests compared to information about the safety of drugs.
The effect of spectral filters on visual search in stroke patients.
Beasley, Ian G; Davies, Leon N
2013-01-01
Visual search impairment can occur following stroke. The utility of optimal spectral filters on visual search in stroke patients has not been considered to date. The present study measured the effect of optimal spectral filters on visual search response time and accuracy, using a task requiring serial processing. A stroke and control cohort undertook the task three times: (i) using an optimally selected spectral filter; (ii) the subjects were randomly assigned to two groups with group 1 using an optimal filter for two weeks, whereas group 2 used a grey filter for two weeks; (iii) the groups were crossed over with group 1 using a grey filter for a further two weeks and group 2 given an optimal filter, before undertaking the task for the final time. Initial use of an optimal spectral filter improved visual search response time but not error scores in the stroke cohort. Prolonged use of neither an optimal nor a grey filter improved response time or reduced error scores. In fact, response times increased with the filter, regardless of its type, for stroke and control subjects; this outcome may be due to contrast reduction or a reflection of task design, given that significant practice effects were noted.
Application of filtering techniques in preprocessing magnetic data
NASA Astrophysics Data System (ADS)
Liu, Haijun; Yi, Yongping; Yang, Hongxia; Hu, Guochuang; Liu, Guoming
2010-08-01
High precision magnetic exploration is a popular geophysical technique for its simplicity and its effectiveness. The explanation in high precision magnetic exploration is always a difficulty because of the existence of noise and disturbance factors, so it is necessary to find an effective preprocessing method to get rid of the affection of interference factors before further processing. The common way to do this work is by filtering. There are many kinds of filtering methods. In this paper we introduced in detail three popular kinds of filtering techniques including regularized filtering technique, sliding averages filtering technique, compensation smoothing filtering technique. Then we designed the work flow of filtering program based on these techniques and realized it with the help of DELPHI. To check it we applied it to preprocess magnetic data of a certain place in China. Comparing the initial contour map with the filtered contour map, we can see clearly the perfect effect our program. The contour map processed by our program is very smooth and the high frequency parts of data are disappeared. After filtering, we separated useful signals and noisy signals, minor anomaly and major anomaly, local anomaly and regional anomaly. It made us easily to focus on the useful information. Our program can be used to preprocess magnetic data. The results showed the effectiveness of our program.
Recent Advances on Endocrine Disrupting Effects of UV Filters.
Wang, Jiaying; Pan, Liumeng; Wu, Shenggan; Lu, Liping; Xu, Yiwen; Zhu, Yanye; Guo, Ming; Zhuang, Shulin
2016-08-03
Ultraviolet (UV) filters are used widely in cosmetics, plastics, adhesives and other industrial products to protect human skin or products against direct exposure to deleterious UV radiation. With growing usage and mis-disposition of UV filters, they currently represent a new class of contaminants of emerging concern with increasingly reported adverse effects to humans and other organisms. Exposure to UV filters induce various endocrine disrupting effects, as revealed by increasing number of toxicological studies performed in recent years. It is necessary to compile a systematic review on the current research status on endocrine disrupting effects of UV filters toward different organisms. We therefore summarized the recent advances on the evaluation of the potential endocrine disruptors and the mechanism of toxicity for many kinds of UV filters such as benzophenones, camphor derivatives and cinnamate derivatives.
Batterman, S; Du, L; Mentz, G; Mukherjee, B; Parker, E; Godwin, C; Chin, J-Y; O'Toole, A; Robins, T; Rowe, Z; Lewis, T
2012-06-01
This study, a randomized controlled trial, evaluated the effectiveness of free-standing air filters and window air conditioners (ACs) in 126 low-income households of children with asthma. Households were randomized into a control group, a group receiving a free-standing HEPA filter placed in the child's sleeping area, and a group receiving the filter and a window-mounted AC. Indoor air quality (IAQ) was monitored for week-long periods over three to four seasons. High concentrations of particulate matter (PM) and carbon dioxide were frequently seen. When IAQ was monitored, filters reduced PM levels in the child's bedroom by an average of 50%. Filter use varied greatly among households and declined over time, for example, during weeks when pollutants were monitored, filter use was initially high, averaging 84±27%, but dropped to 63±33% in subsequent seasons. In months when households were not visited, use averaged only 34±30%. Filter effectiveness did not vary in homes with central or room ACs. The study shows that measurements over multiple seasons are needed to characterize air quality and filter performance. The effectiveness of interventions using free-standing air filters depends on occupant behavior, and strategies to ensure filter use should be an integral part of interventions. Environmental tobacco smoke (ETS) increased particulate matter (PM) levels by about 14 μg/m3 and was often detected using ETS-specific tracers despite restrictions on smoking in the house as reported on questionnaires administered to caregivers. PM concentrations depended on season, filter usage, relative humidity, air exchange ratios, number of children, outdoor PM levels, sweeping/dusting, and presence of a central air conditioner (AC). Free-standing air filters can be an effective intervention that provides substantial reductions in PM concentrations if the filters are used. However, filter use was variable across the study population and declined over the study duration, and thus strategies are needed to encourage and maintain use of filters. The variability in filter use suggests that exposure misclassification is a potential problem in intervention studies using filters. The installation of a room AC in the bedroom, intended to limit air exchange ratios, along with an air filter, did not lower PM levels more than the filter alone. © 2011 John Wiley & Sons A/S.
Chemical UV Filters Mimic the Effect of Progesterone on Ca2+ Signaling in Human Sperm Cells.
Rehfeld, A; Dissing, S; Skakkebæk, N E
2016-11-01
Progesterone released by cumulus cells surrounding the egg induces a Ca 2+ influx into human sperm cells via the cationic channel of sperm (CatSper) Ca 2+ channel and controls multiple Ca 2+ -dependent responses essential for fertilization. We hypothesized that chemical UV filters may mimic the physiological action of progesterone on CatSper, thus affecting Ca 2+ signaling in human sperm cells. We examined 29 UV filters allowed in sunscreens in the United States and/or the European Union for their ability to induce Ca 2+ signals in human sperm by applying measurements of the intracellular free Ca 2+ concentration. We found that 13 UV filters induced a significant Ca 2+ signal at 10 μM. Nine UV filters induced Ca 2+ signals primarily by activating the CatSper channel. The UV filters 3-benzylidene camphor (3-BC) and benzylidene camphor sulfonic acid competitively inhibited progesterone-induced Ca 2+ signals. Dose-response relations for the UV filters showed that the Ca 2+ signal-inducing effects began in the nanomolar-micromolar range. Single-cell Ca 2+ measurements showed a Ca 2+ signal-inducing effect of the most potent UV filter, 3-BC, at 10 nM. Finally, we demonstrated that the 13 UV filters acted additively in low-dose mixtures to induce Ca 2+ signals. In conclusion, 13 of 29 examined UV filters (44%) induced Ca 2+ signals in human sperm. Nine UV filters primarily activated CatSper and thereby mimicked the effect of progesterone. The UV filters 3-BC and benzylidene camphor sulfonic acid competitively inhibited progesterone-induced Ca 2+ signals. In vivo exposure studies are needed to investigate whether UV filter exposure affects human fertility.
Recent Advances on Endocrine Disrupting Effects of UV Filters
Wang, Jiaying; Pan, Liumeng; Wu, Shenggan; Lu, Liping; Xu, Yiwen; Zhu, Yanye; Guo, Ming; Zhuang, Shulin
2016-01-01
Ultraviolet (UV) filters are used widely in cosmetics, plastics, adhesives and other industrial products to protect human skin or products against direct exposure to deleterious UV radiation. With growing usage and mis-disposition of UV filters, they currently represent a new class of contaminants of emerging concern with increasingly reported adverse effects to humans and other organisms. Exposure to UV filters induce various endocrine disrupting effects, as revealed by increasing number of toxicological studies performed in recent years. It is necessary to compile a systematic review on the current research status on endocrine disrupting effects of UV filters toward different organisms. We therefore summarized the recent advances on the evaluation of the potential endocrine disruptors and the mechanism of toxicity for many kinds of UV filters such as benzophenones, camphor derivatives and cinnamate derivatives. PMID:27527194
REPORT OF ON-SITE INSPECTION WORKSHOP-16
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sweeney, J J
2009-07-07
The central issue addressed by this workshop was the task of making the on-site inspection (OSI) part of the Comprehensive Nuclear-Test-Ban Treaty verification system operationally ready at entry into force of the Treaty. It is recognized, and this was emphasized by the 2008 OSI Integrated Field Exercise (IFE), that it is not possible to develop every part of the OSI regime simultaneously. Therefore, it is necessary to prioritize the approach to OSI readiness. The reviews of the IFE have pointed to many elements of OSI readiness that still need development. The objective of this workshop was to provide priorities formore » the path forward for Working Group B to consider. Several critical areas have been identified that are related to the development of OSI readiness: (1) Technology development: Priorities are radionuclide and noble gas sampling and analysis, visual observation, multispectral/infrared imaging methods, active seismic methods and the recognition of the importance of signatures. (2) Organizational development: Priorities are health and safety, the Operations Support Centre, the Equipment Storage and Maintenance Facility, information technology data flow and communications. (3) Resources: The expertise to develop key parts of the OSI regime is not available within the current OSI Division staff. To develop these aspects of the regime will require more staff or supplements to the staff with cost-free experts or other means. Aspects of the system that could benefit from more staff include radionuclide and noble gas detection methods, data flow and communications, visual observation, multispectral/infrared methods and health and safety. As the path forward, participants of this workshop recognized a need to optimize the development of OSI priorities. The outcome of this workshop is to suggest for consideration an operational approach to OSI readiness that utilizes results of an evaluation of the relative effectiveness of OSI elements versus their relative maturity. By integrating such an assessment with considerations of integrated operational capabilities and the anticipated level of inspection team self-sufficiency and measurable milestone criteria, a set of priorities for OSI development can be developed. Once these priorities have been established, the Policy Making Organs can decide upon the milestones, strategic plan and action plan to serve as guidance for implementation by the Provisional Technical Secretariat. The suggested operational approach is as follows: (1) Assess the relative effectiveness (importance) of OSI elements versus their relative maturity; (2) Determine the anticipated level of self-sufficiency; (3) Define measurable milestone criteria; and (4) Result: Milestones for OSI readiness.« less
Batterman, S.; Du, L.; Mentz, G.; Mukherjee, B.; Parker, E.; Godwin, C.; Chin, J.-Y.; O'Toole, A.; Robins, T.; Rowe, Z.; Lewis, T.
2014-01-01
This study, a randomized controlled trial, evaluated the effectiveness of free-standing air filters and window air conditioners (ACs) in 126 low-income households of children with asthma. Households were randomized into a control group, a group receiving a free-standing HEPA filter placed in the child's sleeping area, and a group receiving the filter and a window-mounted AC. Indoor air quality (IAQ) was monitored for week-long periods over three to four seasons. High concentrations of particulate matter (PM) and carbon dioxide were frequently seen. When IAQ was monitored, filters reduced PM levels in the child's bedroom by an average of 50%. Filter use varied greatly among households and declined over time, for example, during weeks when pollutants were monitored, filter use was initially high, averaging 84 ± 27%, but dropped to 63 ± 33% in subsequent seasons. In months when households were not visited, use averaged only 34 ± 30%. Filter effectiveness did not vary in homes with central or room ACs. The study shows that measurements over multiple seasons are needed to characterize air quality and filter performance. The effectiveness of interventions using free-standing air filters depends on occupant behavior, and strategies to ensure filter use should be an integral part of interventions. PMID:22145709
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sweeney, J. J.; Ford, S. R.
The experience of IFE14 emphasizes the need for a better way to simulate aftershocks during an OSI exercise. The obvious approach is to develop a digital model of aftershocks that can be used either for a real field exercise or for a computer simulation that can be done in an office, for training for example. However, this approach involves consideration of several aspects, such as how and when to introduce waveforms in a way that maximizes the realism of the data and that will be convincing to a savvy, experienced seismic analyst. The purpose of this report is to outlinemore » a plan for how this approach can be implemented.« less
The effects of clutter-rejection filtering on estimating weather spectrum parameters
NASA Technical Reports Server (NTRS)
Davis, W. T.
1989-01-01
The effects of clutter-rejection filtering on estimating the weather parameters from pulse Doppler radar measurement data are investigated. The pulse pair method of estimating the spectrum mean and spectrum width of the weather is emphasized. The loss of sensitivity, a measure of the signal power lost due to filtering, is also considered. A flexible software tool developed to investigate these effects is described. It allows for simulated weather radar data, in which the user specifies an underlying truncated Gaussian spectrum, as well as for externally generated data which may be real or simulated. The filter may be implemented in either the time or the frequency domain. The software tool is validated by comparing unfiltered spectrum mean and width estimates to their true values, and by reproducing previously published results. The effects on the weather parameter estimates using simulated weather-only data are evaluated for five filters: an ideal filter, two infinite impulse response filters, and two finite impulse response filters. Results considering external data, consisting of weather and clutter data, are evaluated on a range cell by range cell basis. Finally, it is shown theoretically and by computer simulation that a linear phase response is not required for a clutter rejection filter preceeding pulse-pair parameter estimation.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bujila, R; Royal Institute of Technology, Stockholm; Kull, L
Purpose: Advanced dosimetry in CT (e.g. the Monte Carlo method) requires an accurate characterization of the shaped filter and radiation quality used during a scan. The purpose of this work was to develop a method where half value layer (HVL) profiles along shaped filters could be made. From the HVL profiles the beam shaping properties and effective photon spectrum for a particular scan can be inferred. Methods: A measurement rig was developed to allow determinations of the HVL under a scatter-free narrow-beam geometry and constant focal spot to ionization chamber distance for different fan angles. For each fan angle themore » HVL is obtained by fitting the transmission of radiation through different thicknesses of an Al absorber (type 1100) using an appropriate model. The effective Al thickness of shaped filters and effective photon spectra are estimated using a model of photon emission from a Tungsten anode. This method is used to obtain the effective photon spectra and effective Al thickness of shaped filters for a CT scanner recently introduced to the market. Results: This study resulted in a set of effective photon spectra (central ray) for each kVp along with effective Al thicknesses of the different shaped filters. The effective photon spectra and effective Al thicknesses of shaped filters were used to obtain numerically approximated HVL profiles and compared to measured HVL profiles (mean absolute percentage error = 0.02). The central axis HVL found in the vendor’s technical documentation were compared to approximated HVL values (mean absolute percentage error = 0.03). Conclusion: This work has resulted in a unique method of measuring HVL profiles along shaped filters in CT. Further the effective photon spectra and the effective Al thicknesses of shaped filters that were obtained can be incorporated into Monte Carlo simulations.« less
An optimal search filter for retrieving systematic reviews and meta-analyses
2012-01-01
Background Health-evidence.ca is an online registry of systematic reviews evaluating the effectiveness of public health interventions. Extensive searching of bibliographic databases is required to keep the registry up to date. However, search filters have been developed to assist in searching the extensive amount of published literature indexed. Search filters can be designed to find literature related to a certain subject (i.e. content-specific filter) or particular study designs (i.e. methodological filter). The objective of this paper is to describe the development and validation of the health-evidence.ca Systematic Review search filter and to compare its performance to other available systematic review filters. Methods This analysis of search filters was conducted in MEDLINE, EMBASE, and CINAHL. The performance of thirty-one search filters in total was assessed. A validation data set of 219 articles indexed between January 2004 and December 2005 was used to evaluate performance on sensitivity, specificity, precision and the number needed to read for each filter. Results Nineteen of 31 search filters were effective in retrieving a high level of relevant articles (sensitivity scores greater than 85%). The majority achieved a high degree of sensitivity at the expense of precision and yielded large result sets. The main advantage of the health-evidence.ca Systematic Review search filter in comparison to the other filters was that it maintained the same level of sensitivity while reducing the number of articles that needed to be screened. Conclusions The health-evidence.ca Systematic Review search filter is a useful tool for identifying published systematic reviews, with further screening to identify those evaluating the effectiveness of public health interventions. The filter that narrows the focus saves considerable time and resources during updates of this online resource, without sacrificing sensitivity. PMID:22512835
A design aid for sizing filter strips using buffer area ratio
M.G. Dosskey; M.J. Helmers; D.E. Eisenhauer
2011-01-01
Nonuniform field runoff can reduce the effectiveness of filter strips that are a uniform size along a field margin. Effectiveness can be improved by placing more filter strip where the runoff load is greater and less where the load is smaller. A modeling analysis was conducted of the relationship between pollutant trapping efficiency and the ratio of filter strip area...
Liu, Jingfei; Declercq, Nico F
2017-03-01
An analytical and experimental study of the pulsed ultrasonic comb filtering effect is presented in this work intending to provide a fundamental tool for data analysis and phenomenon understanding in pulsed ultrasonics. The basic types of comb filter, feedforward and feedback filters, are numerically simulated and demonstrated. The characteristic features of comb filters, which include the formula for determining the locations of the spectral peaks or notches and the relationship between its temporal characteristics (relative time delay between constituent pulses) and its spectral characteristics (frequency interval between peaks or notches), are theoretically derived. To demonstrate the applicability of the comb filtering effect, it is applied to measuring the sound velocities and thickness of a thin plate sample. It is proven that the comb filtering effect based method not only is capable of accurate measurements, but also has advantages over the conventional time-of-flight based method in thin plate measurements. Furthermore, the principles developed in this study have potential applications in any pulsed ultrasonic cases where the output signal shows comb filter features. Copyright © 2016 Elsevier B.V. All rights reserved.
Kang, Jieun; Kim, Seon Ok; Oh, Yeon-Mok; Lee, Sang-Do; Lee, Jae Seung
2018-05-17
Malignancy is associated with an increased risk of venous thromboembolism. Inferior vena cava filters are a viable alternative when anticoagulation is infeasible because of the risk of bleeding. Although the current guidelines recommend that all patients with a vena cava filter be treated with anticoagulation treatment when the risk of bleeding is reduced, studies concerning the role of concomitant anticoagulation after vena cava filter insertion in high-risk patients are scarce. Since many cancer patients suffer from a high risk of hemorrhagic complications, we aimed to determine the effect of post-filter anticoagulation on mortality in patients with a malignant solid tumor. A retrospective cohort study of patients with pulmonary embolism was performed between January 2010 and May 2016. Patients with a solid tumor and vena cava filter inserted because of pulmonary embolism were included. Using Cox proportional hazards model, the prognostic effect of clinical variables was analyzed. A total of 180 patients were analyzed, with 143 patients receiving and 37 patients not receiving post-filter anticoagulation treatment. Mortality was not significantly different between the two groups. The presence of metastatic cancer and that of pancreatobiliary cancer were significant risk factors for mortality. However, post-filter anticoagulation did not show significant effect on mortality regardless of the stage of cancer. In patients with cancer-associated pulmonary embolism, the effect of post-filter anticoagulation on mortality may not be critical, especially in patients with a short life expectancy.
Effectiveness of in-room air filtration and dilution ventilation for tuberculosis infection control.
Miller-Leiden, S; Lobascio, C; Nazaroff, W W; Macher, J M
1996-09-01
Tuberculosis (TB) is a public health problem that may pose substantial risks to health care workers and others. TB infection occurs by inhalation of airborne bacteria emitted by persons with active disease. We experimentally evaluated the effectiveness of in-room air filtration systems, specifically portable air filters (PAFs) and ceiling-mounted air filters (CMAFs), in conjunction with dilution ventilation, for controlling TB exposure in high-risk settings. For each experiment, a test aerosol was continuously generated and released into a full-sized room. With the in-room air filter and room ventilation system operating, time-averaged airborne particle concentrations were measured at several points. The effectiveness of in-room air filtration plus ventilation was determined by comparing particle concentrations with and without device operation. The four PAFs and three CMAFs we evaluated reduced room-average particle concentrations, typically by 30% to 90%, relative to a baseline scenario with two air-changes per hour of ventilation (outside air) only. Increasing the rate of air flow recirculating through the filter and/or air flow from the ventilation did not always increase effectiveness. Concentrations were generally higher near the emission source than elsewhere in the room. Both the air flow configuration of the filter and its placement within the room were important, influencing room air flow patterns and the spatial distribution of concentrations. Air filters containing efficient, but non-high efficiency particulate air (HEPA) filter media were as effective as air filters containing HEPA filter media.
Effectiveness of In-Room Air Filtration and Dilution Ventilation for Tuberculosis Infection Control.
Miller-Leiden, S; Lohascio, C; Nazaroff, W W; Macher, J M
1996-09-01
Tuberculosis (TB) is a public health problem that may pose substantial risks to health care workers and others. TB infection occurs by inhalation of airborne bacteria emitted by persons with active disease. We experimentally evaluated the effectiveness of in-room air filtration systems, specifically portable air filters (PAFs) and ceiling-mounted air filters (CMAFs), in conjunction with dilution ventilation, for controlling TB exposure in high-risk settings. For each experiment, a test aerosol was continuously generated and released into a full-sized room. With the in-room air filter and room ventilation system operating, time-averaged airborne particle concentrations were measured at several points. The effectiveness of in-room air filtration plus ventilation was determined by comparing particle concentrations with and without device operation. The four PAFs and three CMAFs we evaluated reduced room-average particle concentrations, typically by 30% to 90%, relative to a baseline scenario with two air-changes per hour of ventilation (outside air) only. Increasing the rate of air flow recirculating through the filter and/or air flow from the ventilation did not always increase effectiveness. Concentrations were generally higher near the emission source than elsewhere in the room. Both the air flow configuration of the filter and its placement within the room were important, influencing room air flow patterns and the spatial distribution of concentrations. Air filters containing efficient, but non-high efficiency particulate air (HEPA) filter media were as effective as air filters containing HEPA filter media.
The inner filter effects and their correction in fluorescence spectra of salt marsh humic matter.
Mendonça, Ana; Rocha, Ana C; Duarte, Armando C; Santos, Eduarda B H
2013-07-25
The inner filter effects in synchronous fluorescence spectra (Δλ=60 nm) of sedimentary humic substances from a salt marsh were studied. Accordingly to their type and the influence of plant colonization, these humic substances have different spectral features and the inner filter effects act in a different manner. The fluorescence spectra of the humic substances from sediments with colonizing plants have a protein like band (λexc=280 nm) which is strongly affected by primary and secondary inner filter effects. These effects were also observed for the bands situated at longer wavelengths, i.e., at λexc=350 nm and λex=454 nm for the fulvic acids (FA) and humic acids (HA), respectively. However, they are more important for the band at 280 nm, causing spectral distortions which can be clearly seen when the spectra of solutions 40 mg L(-1) of different samples (Dissolved Organic Carbon - DOC~20 mg L(-1)) are compared with and without correction of the inner filter effects. The importance of the spectral distortions caused by inner filter effects has been demonstrated in solutions containing a mixture of model compounds which represent the fluorophores detected in the spectra of sedimentary humic samples. The effectiveness of the mathematical correction of the inner filter effects in the spectra of those solutions and of solutions of sedimentary humic substances was studied. It was observed that inner filter effects in the sedimentary humic substances spectra can be mathematically corrected, allowing to obtain a linear relationship between the fluorescence intensity and humic substances concentration and preventing distortions at concentrations as high as 50 mg L(-1) which otherwise would obscure the protein like band. Copyright © 2013 Elsevier B.V. All rights reserved.
Analyses in Support of Z-IFE: LLNL Progress Report for FY-04
DOE Office of Scientific and Technical Information (OSTI.GOV)
Meier, W; Abbott, R; Latkowski, J
2004-10-06
During the last quarter of FY2004, Lawrence Livermore National Laboratory (LLNL) conducted a brief study of power plant options for a z-pinch-based inertial fusion energy (Z-IFE) power plant. Areas that were covered include chamber design, thick-liquid response, neutronics and activation, and systems studies. This report summarizes the progress made in each of these areas, provides recommendations for improvements to the basic design concept, and identifies future work that is needed. As a starting point to the LLNL studies, we have taken information provided in several publications and presentations. In particular, many of the basic parameters were taken from the ZP-3more » study, which is described in reference 4. The ZP-3 design called for 12 separate target chambers, with any 10 of them operating at a given time. Each chamber would be pulsed at a repetition rate of 0.1 Hz with a target yield of 3 GJ. Thus, each chamber would have a fusion power of 300 MW for a power plant total of 3000 MW. The ZP-3 study considered several options for the recyclable transmission lines (RTL). Early in the study, the LLNL group questioned the use of many chambers as well as the yield limitation of 3 GJ. The feeling was that a large number of chambers would invariably lead to a considerably higher system cost than for a system with fewer chambers. Naturally, this trend would be somewhat offset by the increased availability that might be possible with many chambers. Reference 4 points out that target yields as high as 20 GJ would be possible with currently available manufacturing technology. The LLNL team considered yields ranging from 3 to 20 GJ. Our findings indicate that higher yields, which lead one to fewer chambers, make the most sense from an economic point of view. Systems modeling, including relative economics, is covered in Section 2. Regardless of the number of chambers of the fusion yield per target, a Z-IFE power plant would make use of a thick-liquid wall protection scheme. In this type of system a neutronically thick liquid is interspersed between the target and the first structural wall. By doing this, one is able to reduce the neutron damage to the wall to a point at which the wall becomes a lifetime component. This serves to reduce the power plant waste volume (and intensity) as well as increasing the plant availability. We find that a line density of {approx}1 m is needed to reduce the neutron displacement rate to acceptable levels. When a thick-liquid protection scheme is used, several phenomena give rise to significant liquid motion. These include venting, ablation and isochoric heating. Each can lead to strong shocks. Liquid motion and chamber pressurization can cause large stresses, against which the chamber must act. The liquid and chamber responses are covered in Section 3.« less
Gibbons, C D; Rodríguez, R A; Tallon, L; Sobsey, M D
2010-08-01
To evaluate the electropositive, alumina nanofibre (NanoCeram) cartridge filter as a primary concentration method for recovering adenovirus, norovirus and male-specific coliphages from natural seawater. Viruses were concentrated from 40 l of natural seawater using a NanoCeram cartridge filter and eluted from the filter either by soaking the filter in eluent or by recirculating the eluent continuously through the filter using a peristaltic pump. The elution solution consisted of 3% beef extract and 0.1 mol l(-1) of glycine. The method using a peristaltic pump was more effective in removing the viruses from the filter. High recoveries of norovirus and male-specific coliphages (>96%) but not adenovirus (<3%) were observed from seawater. High adsorption to the filter was observed for adenovirus and male-specific coliphages (>98%). The adsorption and recovery of adenovirus and male-specific coliphages were also determined for fresh finished water and source water. The NanoCeram cartridge filter was an effective primary concentration method for the concentration of norovirus and male-specific coliphages from natural seawater, but not for adenovirus, in spite of the high adsorption of adenovirus to the filter. This study demonstrates that NanoCeram cartridge filter is an effective primary method for concentrating noroviruses and male-specific coliphages from seawater, thereby simplifying collection and processing of water samples for virus recovery.
De Vos, Annemarie J B M; Cook, Angus; Devine, Brian; Thompson, Philip J; Weinstein, Philip
2009-01-01
Bushfire smoke contains a range of air toxics. To prevent inhalation of these toxics, fire fighters use respiratory equipment. Yet, little is known about the effectiveness of the equipment on the fire ground. Experimental trials in a smoke chamber demonstrated that, the particulate/organic vapor/formaldehyde (POVF) filter performed best under simulated conditions. This article reports on the field validation trials during prescribed burns in Western Australia. Sixty-seven career fire fighters from the Fire and Emergency Services Authority of Western Australia were allocated one of the three types of filters. Spirometry, oximetry, self-reported symptom, and personal air sampling data were collected before, during and after exposure to bushfire smoke from prescribed burns. Declines in FEV(1) and SaO(2) were demonstrated after 60 and 120 min exposure. A significant higher number of participants in the P filter group reported increases in respiratory symptoms after the exposure. Air sampling inside the respirators demonstrated formaldehyde levels significantly higher in the P filter group compared to the POV and the POVF filter group. The field validation trials during prescribed burns supported the findings from the controlled exposure trials in the smoke chamber. Testing the effectiveness of three types of different filters under bushfire smoke conditions in the field for up to 2 hr demonstrated that the P filter is ineffective in filtering out respiratory irritants. The performance of the POV and the POVF filter appears to be equally effective after 2 hr bushfire smoke exposure in the field.
Long-term effects on symptoms by reducing electric fields from visual display units.
Oftedal, G; Nyvang, A; Moen, B E
1999-10-01
The purpose of the study was to see whether the results of an earlier study [ie, that skin symptoms were reduced by reducing electric fields from visual display units (VDU)] could be reproduced or not. In addition, an attempt was made to determine whether eye symptoms and symptoms from the nervous system could be reduced by reducing VDU electric fields. The study was designed as a controlled double-blind intervention. The electric fields were reduced by using electric-conducting screen filters. Forty-two persons completed the study while working at their ordinary job, first 1 week with no filter, then 3 months with an inactive filter and then 3 months with an active filter (or in reverse order). The inactive filters were identical to the active ones, except that their ground cables were replaced by empty plastic insulation. The inactive filters did not reduce the fields from the VDU. The fields were significantly lower with active filters than with inactive filters. Most of the symptoms were statistically significantly less pronounced in the periods with the filters when compared with the period with no filter. This finding can be explained by visual effects and psychological effects. No statistically significant difference in symptom severeness was observed between the period with an inactive filter and the one with an active filter. The study does not support the hypothesis that skin, eye, or nervous system symptoms can be reduced by reducing VDU electric fields.
Clinical Sequelae of Thrombus in an Inferior Vena Cava Filter
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ahmad, Iftikhar; Yeddula, Kalpana; Wicky, Stephan
The purpose of this study was to assess the long-term clinical sequelae of inferior vena cava (IVC) filter thrombus and the effect of anticoagulation on filter thrombus. Of 1,718 patients who had IVC filters placed during 2001-2008, 598 (34.8%) had follow-up abdominal CT. Filter thrombus was seen in 111 of the 598 (18.6%). There were 44 men (39.6%). The mean age at filter placement was 64 years. The medical diseases included cancer in 64, trauma in 15, stroke in 12, and others in 20. The frequency of filter thrombus on CT and asymptomatic filter thrombus on CT was calculated. Themore » frequency of pulmonary embolism (PE) in patients with filter thrombus was calculated. The frequency of thrombus progression or regression (on CT, available in 56) was calculated. The effect of anticoagulation on filter thrombus regression/progression was evaluated using the Fisher exact test by comparing the group of patients who received anticoagulants versus those who did not. A P-value of <0.05 was considered significant. The overall frequency of filter thrombus was 18.6%. Total occlusion of the IVC filter was seen in 12 of 598 (2%). The filter thrombus was asymptomatic in 110 (18.3%). Filter thrombus was detected after a median of 35 days (range, 0-2082) following filter placement. Thrombus extended above the filter in 4 (3.6%); IVC thrombus below the filter was seen in 35(31.5%). Thrombus in the filter occluded <25% of the filter volume in 58 (52.3%), 25-50% in 21 (18.9%), and 50-75% in 20 (18%). Total IVC occlusion was seen in 12 (10.8%). Eighty-three patients received anticoagulation. Sixteen patients developed symptoms of PE. PE was confirmed on CT in 3 of 15 (2.7%). On follow-up, filter thrombus regressed completely in 19 (33.9%) after a median of 6 months. Filter thrombus decreased in size in 13 (23.2%) and it progressed without IVC occlusion in 7 (12.6%). In one (1.7%), filter thrombus progressed to IVC occlusion. Filter thrombus remained stable in 16 (28.6%). There was no significant difference in thrombus regression or progression rates whether or not the patients received anticoagulation for filter thrombus. In conclusion, asymptomatic thrombus in the filter is common and it rarely progresses to complete caval occlusion. Anticoagulation has little effect on the resolution of filter thrombosis and future occurrence of PE.« less
A recursive solution for a fading memory filter derived from Kalman filter theory
NASA Technical Reports Server (NTRS)
Statman, J. I.
1986-01-01
A simple recursive solution for a class of fading memory tracking filters is presented. A fading memory filter provides estimates of filter states based on past measurements, similar to a traditional Kalman filter. Unlike a Kalman filter, an exponentially decaying weight is applied to older measurements, discounting their effect on present state estimates. It is shown that Kalman filters and fading memory filters are closely related solutions to a general least squares estimator problem. Closed form filter transfer functions are derived for a time invariant, steady state, fading memory filter. These can be applied in loop filter implementation of the Deep Space Network (DSN) Advanced Receiver carrier phase locked loop (PLL).
Microbiological effectiveness of mineral pot filters in Cambodia.
Brown, Joe; Chai, Ratana; Wang, Alice; Sobsey, Mark D
2012-11-06
Mineral pot filters (MPFs) are household water treatment (HWT) devices that are manufactured and distributed by the private sector, with millions of users in Southeast Asia. Their effectiveness in reducing waterborne microbes has not been previously investigated. We purchased three types of MPFs available on the Cambodian market for systematic evaluation of bacteria, virus, and protozoan surrogate microbial reduction in laboratory challenge experiments following WHO recommended performance testing protocols. Results over the total 1500 L testing period per filter indicate that the devices tested were highly effective in reducing Esherichia coli (99.99%+), moderately effective in reducing bacteriophage MS2 (99%+), and somewhat effective against Bacillus atrophaeus, a spore-forming bacterium we used as a surrogate for protozoa (88%+). Treatment mechanisms for all filters included porous ceramic and activated carbon filtration. Our results suggest that these commercially available filters may be at least as effective against waterborne pathogens as other, locally available treatment options such as ceramic pot filters or boiling. More research is needed on the role these devices may play as interim solutions to the problem of unsafe drinking water in Cambodia and globally.
Ojofeitimi, E O
1984-01-01
One hundred and fourteen preschool school children and their 30 mothers from three selected villages in Ile-Ife, Nigeria were assessed for nutritional status using selected and sensitive anthropometric techniques. The mothers' dietary patterns, their perceptions as to components of a good quality of life, infants' immunization status and major cause of infant death were also examined. Approximately 56% of the children and 80% of the women were identified to be suffering from mild to moderate malnutrition. The major cause of infant death as reported by the mothers was high fever and convulsion. Practically all the children under 3 years had not received any form of immunization. Ability to have plenty of children, good health and money, were highly perceived as measures of essential components of quality of life by all the mothers, while 20% listed good feeding, housing, clothing, and only 7% listed potable water. The need for effective health services, regular home visits, supplementary feeding programmes for school children and an effective health education campaign on the importance of immunization and nutrition for rural people are discussed. The training of agricultural extension workers in the use of simple anthropometric techniques to identify covert malnutrition is also highlighted.
Klandima, Somphan; Kruatrachue, Anchalee; Wongtapradit, Lawan; Nithipanya, Narong; Ratanaprakarn, Warangkana
2014-06-01
The problem of image quality in a large number of upper airway obstructed patients is the superimposition of the airway over the bone of the spine on the AP view. This problem was resolved by increasing KVp to high KVp technique and adding extra radiographic filters (copper filter) to reduce the sharpness of the bone and increase the clarity of the airway. However, this raises a concern that patients might be receiving an unnecessarily higher dose of radiation, as well as the effectiveness of the invented filter compared to the traditional filter. To evaluate the level of radiation dose that patients receive with the use of multi-layer filter compared to non-filter and to evaluate the image quality of the upper airways between using the radiographic filter (multi-layer filter) and the traditional filter (copperfilter). The attenuation curve of both filter materials was first identified. Then, both the filters were tested with Alderson Rando phantom to determine the appropriate exposure. Using the method described, a new type of filter called the multi-layer filter for imaging patients was developed. A randomized control trial was then performed to compare the effectiveness of the newly developed multi-layer filter to the copper filter. The research was conducted in patients with upper airway obstruction treated at Queen Sirikit National Institute of Child Health from October 2006 to September 2007. A total of 132 patients were divided into two groups. The experimental group used high kVp technique with multi-layer filter, while the control group used copper filter. A comparison of film interpretation between the multi-layer filter and the copper filter was made by a number of radiologists who were blinded to both to the technique and type of filter used. Patients had less radiation from undergoing the kVp technique with copper filter and multi-layer filter compared to the conventional technique, where no filter is used. Patients received approximately 65.5% less radiation dose using high kVp technique with multi-layer filter compared to the conventional technique, and 25.9% less than using the traditional copper filter 45% of the radiologists who participated in this study reported that the high kVp technique with multi-layer filter was better for diagnosing stenosis, or narrowing of the upper airways. 33% reported that, both techniques were equal, while 22% reported that the traditional copper filter allowed for better details of airway obstruction. These findings showed that the multi-layered filter was comparable to the copper filter in terms of film interpretation. Using the multi-layer filter resulted in patients receiving a lower dose of radiation, as well as similar film interpretation when compared to the traditional copper filter.
Bacterial treatment effectiveness of point-of-use ceramic water filters.
Bielefeldt, Angela R; Kowalski, Kate; Summers, R Scott
2009-08-01
Laboratory experiments were conducted on six point-of-use (POU) ceramic water filters that were manufactured in Nicaragua; two filters were used by families for ca. 4 years and the other filters had limited prior use in our lab. Water spiked with ca. 10(6)CFU/mL of Escherichia coli was dosed to the filters. Initial disinfection efficiencies ranged from 3 - 4.5 log, but the treatment efficiency decreased with subsequent batches of spiked water. Silver concentrations in the effluent water ranged from 0.04 - 1.75 ppb. Subsequent experiments that utilized feed water without a bacterial spike yielded 10(3)-10(5)CFU/mL bacteria in the effluent. Immediately after recoating four of the filters with a colloidal silver solution, the effluent silver concentrations increased to 36 - 45 ppb and bacterial disinfection efficiencies were 3.8-4.5 log. The treatment effectiveness decreased to 0.2 - 2.5 log after loading multiple batches of highly contaminated water. In subsequent loading of clean water, the effluent water contained <20-41 CFU/mL in two of the filters. This indicates that the silver had some benefit to reducing bacterial contamination by the filter. In general these POU filters were found to be effective, but showed loss of effectiveness with time and indicated a release of microbes into subsequent volumes of water passed through the system.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Wang, Shuo; Maillet, Yoann; Wang, Fei
2010-01-01
High-frequency common-mode (CM) electromagnetic-interference (EMI) noise is difficult to suppress in electronics systems. EMI filters are used to suppress CM noise, but their performance is greatly affected by the parasitic effects of the grounding paths. In this paper, the parasitic effects of the grounding paths on an EMI filter's performance are investigated in a motor-drive system. The effects of the mutual inductance between two grounding paths are explored. Guidelines for the grounding of CM EMI filters are derived. Simulations and experiments are finally carried out to verify the theoretical analysis.
Wójcik, Paweł; Adamowski, Janusz
2017-01-01
The spin filtering effect in the bilayer nanowire with quantum point contact is investigated theoretically. We demonstrate the new mechanism of the spin filtering based on the lateral inter-subband spin-orbit coupling, which for the bilayer nanowires has been reported to be strong. The proposed spin filtering effect is explained as the joint effect of the Landau-Zener intersubband transitions caused by the hybridization of states with opposite spin (due to the lateral Rashba SO interaction) and the confinement of carriers in the quantum point contact region. PMID:28358141
Wu, Yan; Aarts, Ronald M.
2018-01-01
A recurring problem regarding the use of conventional comb filter approaches for elimination of periodic waveforms is the degree of selectivity achieved by the filtering process. Some applications, such as the gradient artefact correction in EEG recordings during coregistered EEG-fMRI, require a highly selective comb filtering that provides effective attenuation in the stopbands and gain close to unity in the pass-bands. In this paper, we present a novel comb filtering implementation whereby the iterative filtering application of FIR moving average-based approaches is exploited in order to enhance the comb filtering selectivity. Our results indicate that the proposed approach can be used to effectively approximate the FIR moving average filter characteristics to those of an ideal filter. A cascaded implementation using the proposed approach shows to further increase the attenuation in the filter stopbands. Moreover, broadening of the bandwidth of the comb filtering stopbands around −3 dB according to the fundamental frequency of the stopband can be achieved by the novel method, which constitutes an important characteristic to account for broadening of the harmonic gradient artefact spectral lines. In parallel, the proposed filtering implementation can also be used to design a novel notch filtering approach with enhanced selectivity as well. PMID:29599955
Suppression of Biodynamic Interference by Adaptive Filtering
NASA Technical Reports Server (NTRS)
Velger, M.; Merhav, S. J.; Grunwald, A. J.
1984-01-01
Preliminary experimental results obtained in moving base simulator tests are presented. Both for pursuit and compensatory tracking tasks, a strong deterioration in tracking performance due to biodynamic interference is found. The use of adaptive filtering is shown to substantially alleviate these effects, resulting in a markedly improved tracking performance and reduction in task difficulty. The effect of simulator motion and of adaptive filtering on human operator describing functions is investigated. Adaptive filtering is found to substantially increase pilot gain and cross-over frequency, implying a more tight tracking behavior. The adaptive filter is found to be effective in particular for high-gain proportional dynamics, low display forcing function power and for pursuit tracking task configurations.
Suzuki, T; Hirabayashi, M; Kobayashi, K
1984-01-01
Effects of analog high pass (HP) filtering were compared with those of zero phase-shift digital filtering on the auditory middle latency responses (MLR) from nine adults and 16 young children with normal hearing. Analog HP filtering exerted several prominent effects on the MLR waveforms in both adults and young children, such as suppression of Po (ABR), enhancement of Nb, enhancement or emergence of Pb, and latency decrements for Pa and the later components. Analog HP filtering at 20 Hz produced more pronounced waveform distortions in the responses from young children than from adults. Much greater latency decrements for Pa and Nb were observed for young children than for adults in the analog HP-filtered responses at 20 Hz. A large positive peak (Pb) emerged at about 65 ms after the stimulus onset. From these results, the use of digital HP filtering at 20 Hz is strongly recommended for obtaining unbiased and stable MLR in young children.
Brown, Kathleen Ward; Minegishi, Taeko; Allen, Joseph G; McCarthy, John F; Spengler, John D; MacIntosh, David L
2014-08-01
Many interventions to reduce allergen levels in the home are recommended to asthma and allergy patients. One that is readily available and can be highly effective is the use of high performing filters in forced air ventilation systems. We conducted a modeling analysis of the effectiveness of filter-based interventions in the home to reduce airborne asthma and allergy triggers. This work used "each pass removal efficiency" applied to health-relevant size fractions of particles to assess filter performance. We assessed effectiveness for key allergy and asthma triggers based on applicable particle sizes for cat allergen, indoor and outdoor sources of particles <2.5 µm in diameter (PM2.5), and airborne influenza and rhinovirus. Our analysis finds that higher performing filters can have significant impacts on indoor particle pollutant levels. Filters with removal efficiencies of >70% for cat dander particles, fine particulate matter (PM2.5) and respiratory virus can lower concentrations of those asthma triggers and allergens in indoor air of the home by >50%. Very high removal efficiency filters, such as those rated a 16 on the nationally recognized Minimum Efficiency Removal Value (MERV) rating system, tend to be only marginally more effective than MERV12 or 13 rated filters. The results of this analysis indicate that use of a MERV12 or higher performing air filter in home ventilation systems can effectively reduce indoor levels of these common asthma and allergy triggers. These reductions in airborne allergens in turn may help reduce allergy and asthma symptoms, especially if employed in conjunction with other environmental management measures recommended for allergy and asthma patients.
Minegishi, Taeko; Allen, Joseph G.; McCarthy, John F.; Spengler, John D.; MacIntosh, David L.
2014-01-01
Objective Many interventions to reduce allergen levels in the home are recommended to asthma and allergy patients. One that is readily available and can be highly effective is the use of high performing filters in forced air ventilation systems. Methods We conducted a modeling analysis of the effectiveness of filter-based interventions in the home to reduce airborne asthma and allergy triggers. This work used “each pass removal efficiency” applied to health-relevant size fractions of particles to assess filter performance. We assessed effectiveness for key allergy and asthma triggers based on applicable particle sizes for cat allergen, indoor and outdoor sources of particles <2.5 µm in diameter (PM2.5), and airborne influenza and rhinovirus. Results Our analysis finds that higher performing filters can have significant impacts on indoor particle pollutant levels. Filters with removal efficiencies of >70% for cat dander particles, fine particulate matter (PM2.5) and respiratory virus can lower concentrations of those asthma triggers and allergens in indoor air of the home by >50%. Very high removal efficiency filters, such as those rated a 16 on the nationally recognized Minimum Efficiency Removal Value (MERV) rating system, tend to be only marginally more effective than MERV12 or 13 rated filters. Conclusions The results of this analysis indicate that use of a MERV12 or higher performing air filter in home ventilation systems can effectively reduce indoor levels of these common asthma and allergy triggers. These reductions in airborne allergens in turn may help reduce allergy and asthma symptoms, especially if employed in conjunction with other environmental management measures recommended for allergy and asthma patients. PMID:24555523
PE Padgett
2010-01-01
Nylon and Teflon filter media are frequently used for monitoring ambient air pollutants. These media are subject to many environmental factors that may influence adsorption and retention of particulate and gaseous nitrogenous pollutants. This study evaluated the effects of ozone and humidity on the efficacy of nylon and Teflon filters used in the US dry deposition...
An optimal filter for short photoplethysmogram signals
Liang, Yongbo; Elgendi, Mohamed; Chen, Zhencheng; Ward, Rabab
2018-01-01
A photoplethysmogram (PPG) contains a wealth of cardiovascular system information, and with the development of wearable technology, it has become the basic technique for evaluating cardiovascular health and detecting diseases. However, due to the varying environments in which wearable devices are used and, consequently, their varying susceptibility to noise interference, effective processing of PPG signals is challenging. Thus, the aim of this study was to determine the optimal filter and filter order to be used for PPG signal processing to make the systolic and diastolic waves more salient in the filtered PPG signal using the skewness quality index. Nine types of filters with 10 different orders were used to filter 219 (2.1s) short PPG signals. The signals were divided into three categories by PPG experts according to their noise levels: excellent, acceptable, or unfit. Results show that the Chebyshev II filter can improve the PPG signal quality more effectively than other types of filters and that the optimal order for the Chebyshev II filter is the 4th order. PMID:29714722
LES with and without explicit filtering: comparison and assessment of various models
NASA Astrophysics Data System (ADS)
Winckelmans, Gregoire S.; Jeanmart, Herve; Wray, Alan A.; Carati, Daniele
2000-11-01
The proper mathematical formalism for large eddy simulation (LES) of turbulent flows assumes that a regular ``explicit" filter (i.e., a filter with a well-defined second moment, such as the gaussian, the top hat, etc.) is applied to the equations of fluid motion. This filter is then responsible for a ``filtered-scale" stress. Because of the discretization of the filtered equations, using the LES grid, there is also a ``subgrid-scale" stress. The global effective stress is found to be the discretization of a filtered-scale stress plus a subgrid-scale stress. The former can be partially reconstructed from an exact, infinite, series, the first term of which is the ``tensor-diffusivity" model of Leonard and is found, in practice, to be sufficient for modeling. Alternatively, sufficient reconstruction can also be achieved using the ``scale-similarity" model of Bardina. The latter corresponds to loss of information: it cannot be reconstructed; its effect (essentially dissipation) must be modeled using ad hoc modeling strategies (such as the dynamic version of the ``effective viscosity" model of Smagorinsky). Practitionners also often assume LES without explicit filtering: the effective stress is then only a subgrid-scale stress. We here compare the performance of various LES models for both approaches (with and without explicit filtering), and for cases without solid boundaries: (1) decay of isotropic turbulence; (2) decay of aircraft wake vortices in a turbulent atmosphere. One main conclusion is that better subgrid-scale models are still needed, the effective viscosity models being too active at the large scales.
A target detection multi-layer matched filter for color and hyperspectral cameras
NASA Astrophysics Data System (ADS)
Miyanishi, Tomoya; Preece, Bradley L.; Reynolds, Joseph P.
2018-05-01
In this article, a method for applying matched filters to a 3-dimentional hyperspectral data cube is discussed. In many applications, color visible cameras or hyperspectral cameras are used for target detection where the color or spectral optical properties of the imaged materials are partially known in advance. Therefore, the use of matched filtering with spectral data along with shape data is an effective method for detecting certain targets. Since many methods for 2D image filtering have been researched, we propose a multi-layer filter where ordinary spatially matched filters are used before the spectral filters. We discuss a way to layer the spectral filters for a 3D hyperspectral data cube, accompanied by a detectability metric for calculating the SNR of the filter. This method is appropriate for visible color cameras and hyperspectral cameras. We also demonstrate an analysis using the Night Vision Integrated Performance Model (NV-IPM) and a Monte Carlo simulation in order to confirm the effectiveness of the filtering in providing a higher output SNR and a lower false alarm rate.
Transport of nanoparticles with dispersant through biofilm coated drinking water sand filters.
Li, Zhen; Aly Hassan, Ashraf; Sahle-Demessie, Endalkachew; Sorial, George A
2013-11-01
This article characterizes, experimentally and theoretically, the transport and retention of engineered nanoparticles (NP) through sand filters at drinking water treatment plants (DWTPs) under realistic conditions. The transport of four commonly used NPs (ZnO, CeO2, TiO2, and Ag, with bare surfaces and coating agents) through filter beds filled with sands from either acid washed and calcined, freshly acquired filter media, and used filter media from active filter media, were investigated. The study was conducted using water obtained upstream of the sand filter at DWTP. The results have shown that capping agents have a determinant importance in the colloidal stability and transport of NPs through the different filter media. The presence of the biofilm in used filter media increased adsorption of NPs but its effects in retaining capped NPs was less significant. The data was used to build a mathematical model based on the advection-dispersion equation. The model was used to simulate the performance of a scale-up sand filter and the effects on filtration cycle of traditional sand filtration system used in DWTPs. Published by Elsevier Ltd.
EDC IMPACT: Chemical UV filters can affect human sperm function in a progesterone-like manner
Rehfeld, A; Egeberg, D L; Almstrup, K; Petersen, J H; Dissing, S
2018-01-01
Human sperm cell function must be precisely regulated to achieve natural fertilization. Progesterone released by the cumulus cells surrounding the egg induces a Ca2+ influx into human sperm cells via the CatSper Ca2+-channel and thereby controls sperm function. Multiple chemical UV filters have been shown to induce a Ca2+ influx through CatSper, thus mimicking the effect of progesterone on Ca2+ signaling. We hypothesized that these UV filters could also mimic the effect of progesterone on sperm function. We examined 29 UV filters allowed in sunscreens in the US and/or EU for their ability to affect acrosome reaction, penetration, hyperactivation and viability in human sperm cells. We found that, similar to progesterone, the UV filters 4-MBC, 3-BC, Meradimate, Octisalate, BCSA, HMS and OD-PABA induced acrosome reaction and 3-BC increased sperm penetration into a viscous medium. The capacity of the UV filters to induce acrosome reaction and increase sperm penetration was positively associated with the ability of the UV filters to induce a Ca2+ influx. None of the UV filters induced significant changes in the proportion of hyperactivated cells. In conclusion, chemical UV filters that mimic the effect of progesterone on Ca2+ signaling in human sperm cells can similarly mimic the effect of progesterone on acrosome reaction and sperm penetration. Human exposure to these chemical UV filters may impair fertility by interfering with sperm function, e.g. through induction of premature acrosome reaction. Further studies are needed to confirm the results in vivo. PMID:28874401
EDC IMPACT: Chemical UV filters can affect human sperm function in a progesterone-like manner.
Rehfeld, A; Egeberg, D L; Almstrup, K; Petersen, J H; Dissing, S; Skakkebæk, N E
2018-01-01
Human sperm cell function must be precisely regulated to achieve natural fertilization. Progesterone released by the cumulus cells surrounding the egg induces a Ca 2+ influx into human sperm cells via the CatSper Ca 2+ -channel and thereby controls sperm function. Multiple chemical UV filters have been shown to induce a Ca 2+ influx through CatSper, thus mimicking the effect of progesterone on Ca 2+ signaling. We hypothesized that these UV filters could also mimic the effect of progesterone on sperm function. We examined 29 UV filters allowed in sunscreens in the US and/or EU for their ability to affect acrosome reaction, penetration, hyperactivation and viability in human sperm cells. We found that, similar to progesterone, the UV filters 4-MBC, 3-BC, Meradimate, Octisalate, BCSA, HMS and OD-PABA induced acrosome reaction and 3-BC increased sperm penetration into a viscous medium. The capacity of the UV filters to induce acrosome reaction and increase sperm penetration was positively associated with the ability of the UV filters to induce a Ca 2+ influx. None of the UV filters induced significant changes in the proportion of hyperactivated cells. In conclusion, chemical UV filters that mimic the effect of progesterone on Ca 2+ signaling in human sperm cells can similarly mimic the effect of progesterone on acrosome reaction and sperm penetration. Human exposure to these chemical UV filters may impair fertility by interfering with sperm function, e.g. through induction of premature acrosome reaction. Further studies are needed to confirm the results in vivo . © 2018 The authors.
NASA Astrophysics Data System (ADS)
Michael, Ralph; Wegener, Alfred
2004-08-01
Hazards from the optical radiation of an operating microscope that cause damage at the corneal, lenticular, and retinal levels were investigated; we considered, in particular, ultraviolet radiation (UVR) and blue light. The spectral irradiance from a Zeiss operation microscope OPMI VISU 200 was measured in the corneal plane between 300 and 1100 nm. Effective irradiance and radiance were calculated with relative spectral effectiveness data from the American Conference for Governmental and Industrial Hygienists. Safe exposure time to avoid UVR injury to the lens and cornea was found to be 2 h without a filter, 4 h with a UVR filter, 200 h with a yellow filter, and 400 h with a filter combination. Safe exposure time to avoid retinal photochemical injury was found to be 3 min without a filter and with a UVR filter, 10 min with a yellow filter, and 49 min with a filter combination. The effective radiance limit for retinal thermal injury was not exceeded. The hazard due to the UVR component from the operating microscope is not critical, and operation time can be safely prolonged with the use of appropriate filters. The retinal photochemical hazard appears critical without appropriate filters, permitting only some minutes of safe exposure time. The calculated safe exposure times are for worst-case conditions and maximal light output and include a safety factor.
Michael, Ralph; Wegener, Alfred
2004-08-01
Hazards from the optical radiation of an operating microscope that cause damage at the corneal, lenticular, and retinal levels were investigated; we considered, in particular, ultraviolet radiation (UVR) and blue light. The spectral irradiance from a Zeiss operation microscope OPMI VISU 200 was measured in the corneal plane between 300 and 1100 nm. Effective irradiance and radiance were calculated with relative spectral effectiveness data from the American Conference for Governmental and Industrial Hygienists. Safe exposure time to avoid UVR injury to the lens and cornea was found to be 2 h without a filter, 4 h with a UVR filter, 200 a yellow filter, and 400 h with a filter combination. Safe exposure time to avoid retinal photochemical injury was found to be 3 min without a filter and with a UVR filter, 10 min with a yellow filter, and 49 min with a filter combination. The effective radiance limit for retinal thermal injury was not exceeded. The hazard due to the UVR component from the operating microscope is not critical, and operation time can be safely prolonged with the use of appropriate filters. The retinal photochemical hazard appears critical without appropriate filters, permitting only some minutes of safe exposure time. The calculated safe exposure times are for worst-case conditions and maximal light output and include a safety factor.
NASA Astrophysics Data System (ADS)
Delgado Ramos, Monica Fabiola
The purpose of this research is to design the best lighting that will minimize long term photochemical degradation of Old Master Drawings and/or other works of art, while maintaining the patron's appreciation of the object's color and detail. The present approach is a technological refinement to the basic underlying earlier work on fluorescent lighting by W. A. Thornton, W.A. at General Electric1. Thin-film dielectric, multi-coating technology is used to create filters that eliminate ultraviolet light, near infrared light and significant unnecessary parts from the visible spectrum, thus maximizing the reduction in photochemical degradation, while maintaining optimal color rendering. Three interference filters, were designed and manufactured successfully. The filters are designated Mark 1, Mark 2, & Mark 3. In this dissertation, the filters are analyzed with regard to their performance parameters. This includes color rendering, retardation in fading or color change, beam angle effects, filter stability, perceived brightness, and visual appreciation parameters. To a high confidence level, all three filters are perceived as being indistinguishable from Unfiltered light with regard to the color confusion index parameter (CCI). Subjective assessments by tests subjects suggest the Mark 3 filter may display some distinguishability with a confidence level for distinguishability of 35% for the overall satisfaction parameter. The Mark 3 filter is the most complex three-color type spectral profile and this might be expected due to beam angle effects or departures in accuracy of color theory. Beam angle affects suggest that the Mark 1 and Mark 2 filters do not display significant color rendering aberrations due to Newton's colors interference effects, except possibly at the periphery of the broadest (55-60+°) beam angle lamps. Filtered and Unfiltered light are effectively of the same perceived brightness, though to a low confidence level, Unfiltered light might be perceived brighter. Accelerated aging studies of the filters indicate useful mean time before failures of >20 years. In fact, no failure was observed in any of the accelerated studies, The Mark 2 and Mark 3 filters were evaluated in equal-luminosity studies with regard to their effect on limiting fading of both standard fading samples such as the ISO Blue Wool series, and also other commercial pigments or stains. Within experimental error, the Mark 2 filter either slowed fading or had no effect on fading for all pigments relative to Unfiltered light and OptivexRTM filtered light, OptivexRTM being a common commercial filter used to protect works of art. Mark 3 protected in many cases, but for some pigments it was less protective than OptivexRTM filtered light. This failure is interpreted in terms of the wavelength dependence of the excess light in certain wavelength regions on an equal luminosity condition, and suggests that more subtle wavelength dependent optimizations have to be undertaken for filters which possess significant band separation.
Recursive Implementations of the Consider Filter
NASA Technical Reports Server (NTRS)
Zanetti, Renato; DSouza, Chris
2012-01-01
One method to account for parameters errors in the Kalman filter is to consider their effect in the so-called Schmidt-Kalman filter. This work addresses issues that arise when implementing a consider Kalman filter as a real-time, recursive algorithm. A favorite implementation of the Kalman filter as an onboard navigation subsystem is the UDU formulation. A new way to implement a UDU consider filter is proposed. The non-optimality of the recursive consider filter is also analyzed, and a modified algorithm is proposed to overcome this limitation.
Cooper, Chris; Levay, Paul; Lorenc, Theo; Craig, Gillian M
2014-05-01
This article discusses how hard-to-reach population groups were conceptualized into a search filter. The objectives of this article were to (1) discuss how the authors designed a multistranded population search filter and (2) retrospectively test the effectiveness of the search filter in capturing all relevant populations (eg, homeless people, immigrants, substance misusers) in a public health systematic review. Systematic and retrospective analysis via a case study. Retrospective analysis of the search filter was conducted by comparing the MEDLINE search results retrieved without using the search filter against those retrieved with the search filter. A total of 5,465 additional results from the unfiltered search were screened to the same criteria as the filtered search. No additional populations were identified in the unfiltered sample. The search filter reduced the volume of MEDLINE hits to screen by 64%, with no impact on inclusion of populations. The results demonstrate the effectiveness of the filter in capturing all relevant UK populations for the review. This suggests that well-planned search filters can be written for reviews that analyze imprecisely defined population groups. This filter could be used in topic areas of associated comorbidities, for rapid clinical searches, or for investigating hard-to-reach populations. Copyright © 2014 Elsevier Inc. All rights reserved.
NASA Astrophysics Data System (ADS)
Simonis, J. J.; Basson, A. K.
Africa is one of the most water-scarce continents in the world but it is the lack of potable water which results in diarrhoea being the leading cause of death amongst children under the age of five in Africa (696 million children under 5 years old in Africa contract diarrhoea resulting in 2000 deaths per day: WHO and UNICEF, 2009). Most potable water treatment methods use bulk water treatment not suitable or available to the majority of rural poor in Sub-Saharan Africa. One simple but effective way of making sure that water is of good quality is by purifying it by means of a household ceramic water filter. The making and supply of water filters suitable for the removal of suspended solids, pathogenic bacteria and other toxins from drinking water is therefore critical. A micro-porous ceramic water filter with micron-sized pores was developed using the traditional slip casting process. This locally produced filter has the advantage of making use of less raw materials, cost, labour, energy and expertise and being more effective and efficient than other low cost produced filters. The filter is fitted with a silicone tube inserted into a collapsible bag that acts as container and protection for the filter. Enhanced flow is obtained through this filter system. The product was tested using water inoculated with high concentrations of different bacterial cultures as well as with locally polluted stream water. The filter is highly effective (log10 > 4 with 99.99% reduction efficiency) in providing protection from bacteria and suspended solids found in natural water. With correct cleaning and basic maintenance this filter technology can effectively provide drinking water to rural families affected by polluted surface water sources. This is an African solution for the more than 340 million people in Africa without access to clean drinking water (WHO and UNICEF, 2008).
Hu, Lian; Yang, Zhi; Pan, Xiaojie; Zhao, Na; Peng, Jianhua; Wan, Chengyan
2017-01-01
The effects of stocking both filter-feeding fish and piscivorous fish were compared to the effects of stocking only filter-feeding fish for suppressing algal blooms and improving water quality in the impoundment area of Xiaojiang River where catfish were dominant. Using only filter-feeding fish for algal suppression and water quality control was more effective in the short-term, but use of both filter-feeding fish and piscivorous fish was better in the long-term. Obvious suppression of phytoplankton biomass (PB) only occurred during the first 14 days regardless of the fish stocked. Adding fish to the enclosure clearly alters phytoplankton community structure and introducing piscivorous fish to an enclosure stocked with filter-feeding fish changed the relative densities of dominant algae species. While stocking filter-feeding fish decreased total nitrogen concentration by removing phytoplankton, it did not effectively decrease total phosphorus and Chlorophyll a concentrations. Introducing piscivorous fish to the enclosure weakened the relationship between nutrients and phytoplankton. Results indicate that stocking only filter-feeding fish to improve water quality and suppress phytoplankton in an impoundment area is insufficient and other technologies and means should be applied simultaneously.
Adapted all-numerical correlator for face recognition applications
NASA Astrophysics Data System (ADS)
Elbouz, M.; Bouzidi, F.; Alfalou, A.; Brosseau, C.; Leonard, I.; Benkelfat, B.-E.
2013-03-01
In this study, we suggest and validate an all-numerical implementation of a VanderLugt correlator which is optimized for face recognition applications. The main goal of this implementation is to take advantage of the benefits (detection, localization, and identification of a target object within a scene) of correlation methods and exploit the reconfigurability of numerical approaches. This technique requires a numerical implementation of the optical Fourier transform. We pay special attention to adapt the correlation filter to this numerical implementation. One main goal of this work is to reduce the size of the filter in order to decrease the memory space required for real time applications. To fulfil this requirement, we code the reference images with 8 bits and study the effect of this coding on the performances of several composite filters (phase-only filter, binary phase-only filter). The saturation effect has for effect to decrease the performances of the correlator for making a decision when filters contain up to nine references. Further, an optimization is proposed based for an optimized segmented composite filter. Based on this approach, we present tests with different faces demonstrating that the above mentioned saturation effect is significantly reduced while minimizing the size of the learning data base.
Experimental investigation of air pressure affecting filtration performance of fibrous filter sheet.
Xu, Bin; Yu, Xiao; Wu, Ya; Lin, Zhongping
2017-03-01
Understanding the effect of air pressure on their filtration performance is important for assessing the effectiveness of fibrous filters under different practical circumstances. The effectiveness of three classes of air filter sheets were investigated in laboratory-based measurements at a wide range of air pressures (60-130 KPa). The filtration efficiency was found most sensitive to the air pressure change at smaller particle sizes. As the air pressure increased from 60 to 130 KPa, significant decrease in filtration efficiency (up to 15%) and increase in pressure drop (up to 90 Pa) were observed. The filtration efficiency of the filter sheet with largest fiber diameter and smallest solid volume fraction was affected most, while the pressure drop of the filter sheet with smallest fiber diameter and largest solid volume fraction was affected most. The effect of air pressure on the filtration efficiency was slightly larger at greater filter face air velocity. However, the effect of air pressure on the pressure drop was negligible. The filtration efficiency and pressure drop were explicitly expressed as functions of the air pressure. Two coefficients were empirically derived and successfully accounted for the effects of air pressure on filtration efficiency and pressure drop.
NASA Astrophysics Data System (ADS)
Aguayo-Rodríguez, G.; Zaldívar-Huerta, I. E.; García-Juárez, A.; Rodríguez-Asomoza, J.; Larger, L.; Courjal, N.
2011-01-01
We demonstrate experimentally the efficiency of tuning of a photonic filter in the frequency range of 0.01 to 20 GHz. The presented work combines the use of a multimode optical source associated with a dispersive optical fiber to obtain the filtering effect. Tunability effect is achieved by the use of a Fabry-Perot filter that allows altering the spectral characteristics of the optical source. Experimental results are validated by means of numerical simulations. The scheme here proposed has a potential application in the field of optical telecommunications.
Tunable multimode-interference bandpass fiber filter.
Antonio-Lopez, J E; Castillo-Guzman, A; May-Arrioja, D A; Selvas-Aguilar, R; Likamwa, P
2010-02-01
We report on a wavelength-tunable filter based on multimode interference (MMI) effects. A typical MMI filter consists of a multimode fiber (MMF) spliced between two single-mode fibers (SMF). The peak wavelength response of the filter exhibits a linear dependence when the length of the MMF is modified. Therefore a capillary tube filled with refractive-index-matching liquid is used to effectively increase the length of the MMF, and thus wavelength tuning is achieved. Using this filter a ring-based tunable erbium-doped fiber laser is demonstrated with a tunability of 30 nm, covering the full C-band.
Research on spectroscopic imaging. Volume 1: Technical discussion. [birefringent filters
NASA Technical Reports Server (NTRS)
Title, A.; Rosenberg, W.
1979-01-01
The principals of operation and the capabilities of birefringent filters systems are examined. Topics covered include: Lyot, Solc, and partial polarizer filters; transmission profile management; tuning birefringent filters; field of view; bandpass control; engineering considerations; and recommendations. Improvements for field of view effects, and the development of birefringent filters for spaceflight are discussed in appendices.
Accuracy of telemetry signal power loss in a filter as an estimate for telemetry degradation
NASA Technical Reports Server (NTRS)
Koerner, M. A.
1989-01-01
When telemetry data is transmitted through a communication link, some degradation in telemetry performance occurs as a result of the imperfect frequency response of the channel. The term telemetry degradation as used here is the increase in received signal power required to offset this filtering. The usual approach to assessing this degradation is to assume that it is equal to the signal power loss in the filtering, which is easily calculated. However, this approach neglects the effects of the nonlinear phase response of the filter, the effect of any reduction of the receiving system noise due to the filter, and intersymbol interference. Here, an exact calculation of the telemetry degradation, which includes all of the above effects, is compared with the signal power loss calculation for RF filtering of NRZ data on a carrier. The signal power loss calculation is found to be a reasonable approximation when the filter follows the point at which the receiving system noise is introduced, especially if the signal power loss is less than 0.5 dB. The signal power loss approximation is less valid when the receiving system noise is not filtered.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Medin, Stanislav A.; Basko, Mikhail M.; Orlov, Yurii N.
2012-07-11
Radiation hydrodynamics 1D simulations were performed with two concurrent codes, DEIRA and RAMPHY. The DEIRA code was used for DT capsule implosion and burn, and the RAMPHY code was used for computation of X-ray and fast ions deposition in the first wall liquid film of the reactor chamber. The simulations were run for 740 MJ direct drive DT capsule and Pb thin liquid wall reactor chamber of 10 m diameter. Temporal profiles for DT capsule leaking power of X-rays, neutrons and fast {sup 4}He ions were obtained and spatial profiles of the liquid film flow parameter were computed and analyzed.
SEM Analysis Techniques for LSI Microcircuits. Volume 1
1980-08-01
CHIP, EBIC 70 1-40 COLUMN DECODE FAILURE, VOLTAGE CONTRAST 71 1-41 COLUMN DECODE FAILURE, VOLTAGE CONTRAST 72 1-42 OUTPUT FAILURE, VOLTAGE CONTRAST 73...317 5-22 DATA OUTPUT BUFFER, LIGHT PHOTO 318 5-23 DATA OUTPUT BUFFER, VOLTAGE CONTRAST 319 5-24 OVERALL CHIP FUNCTION, LIGHT PHOTO 320 5-25 ROW...34.. 91 75 87 80 99 93’ 76 71 0.4mA 1 IFA "0" 85 76 88 80 99 94 76 72 0.4mA 15 ’FA Ŕ" 58 42 60 58 64 66 52 48 0.4mA 13 IFE (A) 1101" 54 51 56 60 65 58 47
Next-generation laser for inertial confinement fusion
DOE Office of Scientific and Technical Information (OSTI.GOV)
Marshall, C; Bibeau, C; Bayramian, A
1998-03-13
We are developing and building the ''Mercury'' laser system as the first in a series of a new generation of diode-pumped solid-state lasers (DPSSL) for advanced high energy density (HED) physics experiments at LLNL. Mercury will be the first integrated demonstration of a scalable laser architecture compatible with advanced Inertial Confinement Fusion (ICF) goals. Primary performance goals include 10% efficiencies at 10 Hz and a <10 ns pulse with l {omega} energies of 100 J and with 2 {omega}/3 {omega} frequency conversion. Achieving this performance will provide a near term capability for HED experiments and prove the potential of DPSSLsmore » for inertial fusion energy (IFE).« less
USDA-ARS?s Scientific Manuscript database
Grass filter strips are a widely used conservation practice in the Midwestern United States for reducing nutrient, pesticide, and sediment inputs into agricultural streams. Previous studies have documented the effectiveness of grass filter strips in reducing the input of agricultural pollutants, bu...
USDA-ARS?s Scientific Manuscript database
The cost and effectiveness of three solids thickening processes, i.e., gravity thickening settlers (GTS), inclined belt filters (IBF), geotextile bag filters (GBF), were individually evaluated with the biosolids backwash produced in intensive aquaculture systems equipped with microscreen drum filter...
A P-band SAR interference filter
NASA Technical Reports Server (NTRS)
Taylor, Victor B.
1992-01-01
The synthetic aperture radar (SAR) interference filter is an adaptive filter designed to reduce the effects of interference while minimizing the introduction of undesirable side effects. The author examines the adaptive spectral filter and the improvement in processed SAR imagery using this filter for Jet Propulsion Laboratory Airborne SAR (JPL AIRSAR) data. The quality of these improvements is determined through several data fidelity criteria, such as point-target impulse response, equivalent number of looks, SNR, and polarization signatures. These parameters are used to characterize two data sets, both before and after filtering. The first data set consists of data with the interference present in the original signal, and the second set consists of clean data which has been coherently injected with interference acquired from another scene.
Signal Processing Equipment and Techniques for Use in Measuring Ocean Acoustic Multipath Structures
1983-12-01
Demodulator 3.4 Digital Demodulator 3.4.1 Number of Bits in the Input A/D Converter Quantization Effects The Demodulator Output Filter Effects of... power caused by ignoring cross spectral term a) First order Butterworth filter b) Second order Butterworth filter 48 3.4 Ordering of e...spectrum 59 3.7 Multiplying D/A Converter input and output spectra a) Input b) Output 60 3.8 Demodulator output spectrum prior to filtering 63
Bowtie filters for dedicated breast CT: Theory and computational implementation
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kontson, Kimberly, E-mail: Kimberly.Kontson@fda.hhs.gov; Jennings, Robert J.
Purpose: To design bowtie filters with improved properties for dedicated breast CT to improve image quality and reduce dose to the patient. Methods: The authors present three different bowtie filters designed for a cylindrical 14-cm diameter phantom with a uniform composition of 40/60 breast tissue, which vary in their design objectives and performance improvements. Bowtie design #1 is based on single material spectral matching and produces nearly uniform spectral shape for radiation incident upon the detector. Bowtie design #2 uses the idea of basis material decomposition to produce the same spectral shape and intensity at the detector, using two differentmore » materials. Bowtie design #3 eliminates the beam hardening effect in the reconstructed image by adjusting the bowtie filter thickness so that the effective attenuation coefficient for every ray is the same. All three designs are obtained using analytical computational methods and linear attenuation coefficients. Thus, the designs do not take into account the effects of scatter. The authors considered this to be a reasonable approach to the filter design problem since the use of Monte Carlo methods would have been computationally intensive. The filter profiles for a cone-angle of 0° were used for the entire length of each filter because the differences between those profiles and the correct cone-beam profiles for the cone angles in our system are very small, and the constant profiles allowed construction of the filters with the facilities available to us. For evaluation of the filters, we used Monte Carlo simulation techniques and the full cone-beam geometry. Images were generated with and without each bowtie filter to analyze the effect on dose distribution, noise uniformity, and contrast-to-noise ratio (CNR) homogeneity. Line profiles through the reconstructed images generated from the simulated projection images were also used as validation for the filter designs. Results: Examples of the three designs are presented. Initial verification of performance of the designs was done using analytical computations of HVL, intensity, and effective attenuation coefficient behind the phantom as a function of fan-angle with a cone-angle of 0°. The performance of the designs depends only weakly on incident spectrum and tissue composition. For all designs, the dynamic range requirement on the detector was reduced compared to the no-bowtie-filter case. Further verification of the filter designs was achieved through analysis of reconstructed images from simulations. Simulation data also showed that the use of our bowtie filters can reduce peripheral dose to the breast by 61% and provide uniform noise and CNR distributions. The bowtie filter design concepts validated in this work were then used to create a computational realization of a 3D anthropomorphic bowtie filter capable of achieving a constant effective attenuation coefficient behind the entire field-of-view of an anthropomorphic breast phantom. Conclusions: Three different bowtie filter designs that vary in performance improvements were described and evaluated using computational and simulation techniques. Results indicate that the designs are robust against variations in breast diameter, breast composition, and tube voltage, and that the use of these filters can reduce patient dose and improve image quality compared to the no-bowtie-filter case.« less
Evaluation of Eye Protection Filters Used with Broad-Spectrum and Conventional LED Curing Lights.
Soares, Carlos José; Rodrigues, Monise de Paula; Vilela, Andomar Bruno Fernandes; Rizo, Erick René Cerda; Ferreira, Lorraine Braga; Giannini, Marcelo; Price, Richard Bengt
2017-01-01
The high irradiance and the different emission spectra from contemporary light curing units (LCU) may cause ocular damage. This study evaluated the ability of 15 eye protection filters: 2 glasses, 1 paddle design, and 12 dedicated filters to block out harmful light from a monowave (HP-3M ESPE) and a broad-spectrum (Valo, Ultradent) LED LCU. Using the anterior sensor in the MARC-Patient Simulator (BlueLight Analytics) the irradiance that was delivered through different eye protection filters was measured three times. The LCUs delivered a similar irradiance to the top of the filter. The mean values of the light that passed through the filters as percent of the original irradiance were analyzed using two-way ANOVA followed by Tukey test (a= 0.05). The emission spectra from the LCUs and through the filters were also obtained. Two-way ANOVA showed that the interaction between protective filters and LCUs significantly influenced the amount of light transmitted (p< 0.001). Tukey test showed that the amount of light transmitted through the protective filters when using the HP-3M-ESPE was significantly greater compared to when using the Valo, irrespective of the protective filter tested. When using the HP-3M-ESPE, the Glasses filter allowed significantly more light through, followed by XL 3000, ORTUS, Google Professional, Gnatus filters. The Valo filter was the most effective at blocking out the harmful light. Some protective filters were less effective at blocking the lower wavelengths of light (<420 nm). However, even in the worst scenario, the filters were able to block at least 97% of the irradiance.
Xiao, Mengli; Zhang, Yongbo; Wang, Zhihua; Fu, Huimin
2018-04-01
Considering the performances of conventional Kalman filter may seriously degrade when it suffers stochastic faults and unknown input, which is very common in engineering problems, a new type of adaptive three-stage extended Kalman filter (AThSEKF) is proposed to solve state and fault estimation in nonlinear discrete-time system under these conditions. The three-stage UV transformation and adaptive forgetting factor are introduced for derivation, and by comparing with the adaptive augmented state extended Kalman filter, it is proven to be uniformly asymptotically stable. Furthermore, the adaptive three-stage extended Kalman filter is applied to a two-dimensional radar tracking scenario to illustrate the effect, and the performance is compared with that of conventional three stage extended Kalman filter (ThSEKF) and the adaptive two-stage extended Kalman filter (ATEKF). The results show that the adaptive three-stage extended Kalman filter is more effective than these two filters when facing the nonlinear discrete-time systems with information of unknown inputs not perfectly known. Copyright © 2018 ISA. Published by Elsevier Ltd. All rights reserved.
NASA Astrophysics Data System (ADS)
Buzzicotti, M.; Linkmann, M.; Aluie, H.; Biferale, L.; Brasseur, J.; Meneveau, C.
2018-02-01
The effects of different filtering strategies on the statistical properties of the resolved-to-subfilter scale (SFS) energy transfer are analysed in forced homogeneous and isotropic turbulence. We carry out a-priori analyses of the statistical characteristics of SFS energy transfer by filtering data obtained from direct numerical simulations with up to 20483 grid points as a function of the filter cutoff scale. In order to quantify the dependence of extreme events and anomalous scaling on the filter, we compare a sharp Fourier Galerkin projector, a Gaussian filter and a novel class of Galerkin projectors with non-sharp spectral filter profiles. Of interest is the importance of Galilean invariance and we confirm that local SFS energy transfer displays intermittency scaling in both skewness and flatness as a function of the cutoff scale. Furthermore, we quantify the robustness of scaling as a function of the filtering type.
Sadeghpour, Naser; Alishiri, Ali Agha; Ajudani, Reza; Khosravi, Mohammad Hossein; Amiri, Mohammad Aghazadeh; Sadeghpour, Omid
2015-01-01
To investigate the effect of tinted filters on visual acuity (VA), contrast sensitivity and patient satisfaction in diabetic retinopathy associated with low vision. In a prospective study, 51 patients with diabetic retinopathy and low vision were assessed. We chose a simple random sampling method and used the patient's files for data collection. LogMAR notations were applied for assessing VA and a contrast sensitivity chart (CSV-1000) was employed for measuring contrast sensitivity. First, measurements were performed without tinted filters and then using them. Appropriate lenses were given to the patients for 2 days, and they were questioned about their satisfaction using them in different places. A total of 20 male and 31 female patients with mean age of 57.3 years participated in the study. With a 527 ± 10 nm filter, mean VA improved significantly (P ≤ 0.05). Using the 527 ± 10 nm and 511 ± 10 nm filters, mean contrast sensitivity was improved significantly at 3 and 6 cycles/degree frequencies (P < 0.05). The effect of other filters on VA and contrast sensitivity was not significant. Patient satisfaction rate was generally high. Tinted filters are able to rehabilitate low-vision patients due to diabetic retinopathy. The 527 ± 10 and 511 ± 10 nm wavelength filters improved contrast sensitivity and the 527 ± 10 nm filter improved VA to some extent. Further investigations are recommended to assess the effect of these filters in patients with other causes of low-vision.
Modeling the Sustainability of a Ceramic Water Filter Intervention
Mellor, Jonathan; Abebe, Lydia; Ehdaie, Beeta; Dillingham, Rebecca; Smith, James
2014-01-01
Ceramic water filters (CWFs) are a point-of-use water treatment technology that has shown promise in preventing early childhood diarrhea (ECD) in resource-limited settings. Despite this promise, some researchers have questioned their ability to reduce ECD incidences over the long term since most effectiveness trials conducted to date are less than one year in duration limiting their ability to assess long-term sustainability factors. Most trials also suffer from lack of blinding making them potentially biased. This study uses an agent-based model (ABM) to explore factors related to the long-term sustainability of CWFs in preventing ECD and was based on a three year longitudinal field study. Factors such as filter user compliance, microbial removal effectiveness, filter cleaning and compliance declines were explored. Modeled results indicate that broadly defined human behaviors like compliance and declining microbial effectiveness due to improper maintenance are primary drivers of the outcome metrics of household drinking water quality and ECD rates. The model predicts that a ceramic filter intervention can reduce ECD incidence amongst under two year old children by 41.3%. However, after three years, the average filter is almost entirely ineffective at reducing ECD incidence due to declining filter microbial removal effectiveness resulting from improper maintenance. The model predicts very low ECD rates are possible if compliance rates are 80-90%, filter log reduction efficiency is 3 or greater and there are minimal long-term compliance declines. Cleaning filters at least once every 4 months makes it more likely to achieve very low ECD rates as does the availability of replacement filters for purchase. These results help to understand the heterogeneity seen in previous intervention-control trials and reemphasize the need for researchers to accurately measure confounding variables and ensure that field trials are at least 2-3 years in duration. In summary, the CWF can be a highly effective tool in the fight against ECD, but every effort should be made by implementing agencies to ensure consistent use and maintenance. PMID:24355289
NASA Technical Reports Server (NTRS)
Bailey, R. E.; Smith, R. E.
1982-01-01
An investigation of pilot-induced oscillation suppression (PIOS) filters was performed using the USAF/Flight Dynamics Laboratory variable stability NT-33 aircraft, modified and operated by Calspan. This program examined the effects of PIOS filtering on the longitudinal flying qualities of fighter aircraft during the visual approach and landing task. Forty evaluations were flown to test the effects of different PIOS filters. Although detailed analyses were not undertaken, the results indicate that PIOS filtering can improve the flying qualities of an otherwise unacceptable aircraft configuration (Level 3 flying qualities). However, the ability of the filters to suppress pilot-induced oscillations appears to be dependent upon the aircraft configuration characteristics. Further, the data show that the filters can adversely affect landing flying qualities if improperly designed. The data provide an excellent foundation from which detail analyses can be performed.
Arbitrary-shaped Brillouin microwave photonic filter by manipulating a directly modulated pump.
Wei, Wei; Yi, Lilin; Jaouën, Yves; Hu, Weisheng
2017-10-15
We present a cost-effective gigahertz-wide arbitrary-shaped microwave photonic filter based on stimulated Brillouin scattering in fiber using a directly modulated laser (DML). After analyzing the relationship between the spectral power density and the modulation current of the DML, we manage to precisely adjust the optical spectrum of the DML, thereby controlling the Brillouin filter response arbitrarily for the first time, to the best of our knowledge. The filter performance is evaluated by amplifying a 500 Mb/s non-return-to-zero on-off keying signal using a 1 GHz rectangular filter. The comparison between the proposed DML approach and the previous approach adopting a complex IQ modulator shows similar filter flexibility, shape fidelity, and noise performance, proving that the DML-based Brillouin filter technique is a cost-effective and valid solution for microwave photonic applications.
NASA Technical Reports Server (NTRS)
Full, William E.; Eppler, Duane T.
1993-01-01
The effectivity of multichannel Wiener filters to improve images obtained with passive microwave systems was investigated by applying Wiener filters to passive microwave images of first-year sea ice. Four major parameters which define the filter were varied: the lag or pixel offset between the original and the desired scenes, filter length, the number of lines in the filter, and the weight applied to the empirical correlation functions. The effect of each variable on the image quality was assessed by visually comparing the results. It was found that the application of multichannel Wiener theory to passive microwave images of first-year sea ice resulted in visually sharper images with enhanced textural features and less high-frequency noise. However, Wiener filters induced a slight blocky grain to the image and could produce a type of ringing along scan lines traversing sharp intensity contrasts.
The Entrance and Exit Effects in Small Electrochemical Filter-Press Reactors Used in the Laboratory
ERIC Educational Resources Information Center
Frias-Ferrer, Angel; Gonzalez-Garcia, Jose; Saez, Veronica; Exposito, Eduardo; Sanchez-Sanchez, Carlos M.; Mantiel, Vicente; Walsh, Frank C.; Aldaz, Antonio; Walsh, Frank C.
2005-01-01
A laboratory experiment designed to examine the entrance and exit effects in small electrochemical filter-press reactors used in the laboratory is presented. The single compartment of the filter-press reactor is filled with different turbulence promoters to study their influence as compared to the empty configuration.
Equalizing secondary path effects using the periodicity of fMRI acoustic noise.
Kannan, Govind; Milani, Ali A; Panahi, Issa; Briggs, Richard
2008-01-01
Non-minimum phase secondary path has a direct effect on achieving a desired noise attenuation level in active noise control (ANC) systems. The adaptive noise canceling filter is often a causal FIR filter which may not be able to sufficiently equalize the effect of a non-minimum phase secondary path, since in theory only a non-causal filter can equalize it. However a non-causal stable filter can be found to equalize the non-minimum phase effect of secondary path. Realization of non-causal stable filters requires knowledge of future values of input signal. In this paper we develop methods for equalizing the non-minimum phase property of the secondary path and improving the performance of an ANC system by exploiting the periodicity of fMRI acoustic noise. It has been shown that the scanner noise component is highly periodic and hence predictable which enables easy realization of non-causal filtering. Improvement in performance due to the proposed methods (with and without the equalizer) is shown for periodic fMRI acoustic noise.
The Effects of Filter Cutoff Frequency on Musculoskeletal Simulations of High-Impact Movements.
Tomescu, Sebastian; Bakker, Ryan; Beach, Tyson A C; Chandrashekar, Naveen
2018-02-12
Estimation of muscle forces through musculoskeletal simulation is important in understanding human movement and injury. Unmatched filter frequencies used to low-pass filter marker and force platform data can create artifacts during inverse dynamics analysis, but their effects on muscle force calculations are unknown. The objective of this study was to determine the effects of filter cutoff frequency on simulation parameters and magnitudes of lower extremity muscle and resultant joint contact forces during a high-impact maneuver. Eight participants performed a single leg jump-landing. Kinematics were captured with a 3D motion capture system and ground reaction forces were recorded with a force platform. The marker and force platform data were filtered using two matched filter frequencies (10-10Hz, 15-15Hz) and two unmatched frequencies (10-50Hz, 15-50Hz). Musculoskeletal simulations using Computed Muscle Control were performed in OpenSim. The results revealed significantly higher peak quadriceps (13%), hamstrings (48%), and gastrocnemius forces (69%) in the unmatched (10-50Hz, 15-50Hz) conditions than in the matched (10-10Hz, 15-15Hz) conditions (p<0.05). Resultant joint contact forces and reserve (non-physiologic) moments were similarly larger in the unmatched filter categories (p<0.05). This study demonstrated that artifacts created from filtering with unmatched filter cutoffs result in altered muscle forces and dynamics which are not physiologic.
NASA Astrophysics Data System (ADS)
Ren, Zhong; Liu, Guodong; Huang, Zhen
2012-11-01
The image reconstruction is a key step in medical imaging (MI) and its algorithm's performance determinates the quality and resolution of reconstructed image. Although some algorithms have been used, filter back-projection (FBP) algorithm is still the classical and commonly-used algorithm in clinical MI. In FBP algorithm, filtering of original projection data is a key step in order to overcome artifact of the reconstructed image. Since simple using of classical filters, such as Shepp-Logan (SL), Ram-Lak (RL) filter have some drawbacks and limitations in practice, especially for the projection data polluted by non-stationary random noises. So, an improved wavelet denoising combined with parallel-beam FBP algorithm is used to enhance the quality of reconstructed image in this paper. In the experiments, the reconstructed effects were compared between the improved wavelet denoising and others (directly FBP, mean filter combined FBP and median filter combined FBP method). To determine the optimum reconstruction effect, different algorithms, and different wavelet bases combined with three filters were respectively test. Experimental results show the reconstruction effect of improved FBP algorithm is better than that of others. Comparing the results of different algorithms based on two evaluation standards i.e. mean-square error (MSE), peak-to-peak signal-noise ratio (PSNR), it was found that the reconstructed effects of the improved FBP based on db2 and Hanning filter at decomposition scale 2 was best, its MSE value was less and the PSNR value was higher than others. Therefore, this improved FBP algorithm has potential value in the medical imaging.
Comparison of Filters Dedicated to Speckle Suppression in SAR Images
NASA Astrophysics Data System (ADS)
Kupidura, P.
2016-06-01
This paper presents the results of research on the effectiveness of different filtering methods dedicated to speckle suppression in SAR images. The tests were performed on RadarSat-2 images and on an artificial image treated with simulated speckle noise. The research analysed the performance of particular filters related to the effectiveness of speckle suppression and to the ability to preserve image details and edges. Speckle is a phenomenon inherent to radar images - a deterministic noise connected with land cover type, but also causing significant changes in digital numbers of pixels. As a result, it may affect interpretation, classification and other processes concerning radar images. Speckle, resembling "salt and pepper" noise, has the form of a set of relatively small groups of pixels of values markedly different from values of other pixels representing the same type of land cover. Suppression of this noise may also cause suppression of small image details, therefore the ability to preserve the important parts of an image, was analysed as well. In the present study, selected filters were tested, and methods dedicated particularly to speckle noise suppression: Frost, Gamma-MAP, Lee, Lee-Sigma, Local Region, general filtering methods which might be effective in this respect: Mean, Median, in addition to morphological filters (alternate sequential filters with multiple structuring element and by reconstruction). The analysis presented in this paper compared the effectiveness of different filtering methods. It proved that some of the dedicated radar filters are efficient tools for speckle suppression, but also demonstrated a significant efficiency of the morphological approach, especially its ability to preserve image details.
New Predictive Filters for Compensating the Transport Delay on a Flight Simulator
NASA Technical Reports Server (NTRS)
Guo, Liwen; Cardullo, Frank M.; Houck, Jacob A.; Kelly, Lon C.; Wolters, Thomas E.
2004-01-01
The problems of transport delay in a flight simulator, such as its sources and effects, are reviewed. Then their effects on a pilot-in-the-loop control system are investigated with simulations. Three current prominent delay compensators the lead/lag filter, McFarland filter, and the Sobiski/Cardullo filter were analyzed and compared. This paper introduces two novel delay compensation techniques an adaptive predictor using the Kalman estimator and a state space predictive filter using a reference aerodynamic model. Applications of these two new compensators on recorded data from the NASA Langley Research Center Visual Motion Simulator show that they achieve better compensation over the current ones.
A Structural and Content-Based Analysis for Web Filtering.
ERIC Educational Resources Information Center
Lee, P. Y.; Hui, S. C.; Fong, A. C. M.
2003-01-01
Presents an analysis of the distinguishing features of pornographic Web pages so that effective filtering techniques can be developed. Surveys the existing techniques for Web content filtering and describes the implementation of a Web content filtering system that uses an artificial neural network. (Author/LRW)
The effect of spectral filters on VEP and alpha-wave responses.
Willeford, Kevin T; Fimreite, Vanessa; Ciuffreda, Kenneth J
2016-01-01
Spectral filters are used to treat light sensitivity in individuals with traumatic brain injury (TBI); however, the effect of these filters on normal visual function has not been elucidated. Thus, the current study aimed to determine the effect of spectral filters on objectively-measured visual-evoked potential (VEP) and alpha-wave responses in the visually-normal population. The full-field (15°H×17°V), pattern-reversal VEP (20' check size, mean luminance 52cd/m(2)) was administered to 20 visually-normal individuals. They were tested with four Intuitive-Colorimeter-derived, broad-band, spectral filters (i.e., gray/neutral density, blue, yellow, and red), which produced similar luminance values for the test stimulus. The VEP N75 and P100 latencies, and VEP amplitude, were recorded. Power spectrum analysis was used to derive the respective powers at each frequency, and peak frequency, for the selected 9-11Hz components of the alpha band. Both N75 and P100 latencies increased with the addition of each filter when compared to baseline. Additionally, each filter numerically reduced intra-session amplitude variability relative to baseline. There were no significant effects on either the mean VEP amplitude or alpha wave parameters. The Intuitive Colorimeter filters significantly increased both N75 and P100 latencies, an effect which is primarily attributable (∼75%) to luminance, and in some cases, specific spectral effects (e.g., blue and red). VEP amplitude and alpha power were not significantly affected. These findings provide an important reference to which either amplitude or power changes in light-sensitive, younger clinical groups can be compared. Copyright © 2015 Spanish General Council of Optometry. Published by Elsevier Espana. All rights reserved.
The effect of spectral filters on VEP and alpha-wave responses
Willeford, Kevin T.; Fimreite, Vanessa; Ciuffreda, Kenneth J.
2015-01-01
Purpose Spectral filters are used to treat light sensitivity in individuals with traumatic brain injury (TBI); however, the effect of these filters on normal visual function has not been elucidated. Thus, the current study aimed to determine the effect of spectral filters on objectively-measured visual-evoked potential (VEP) and alpha-wave responses in the visually-normal population. Methods The full-field (15°H × 17°V), pattern-reversal VEP (20′ check size, mean luminance 52 cd/m2) was administered to 20 visually-normal individuals. They were tested with four Intuitive-Colorimeter-derived, broad-band, spectral filters (i.e., gray/neutral density, blue, yellow, and red), which produced similar luminance values for the test stimulus. The VEP N75 and P100 latencies, and VEP amplitude, were recorded. Power spectrum analysis was used to derive the respective powers at each frequency, and peak frequency, for the selected 9–11 Hz components of the alpha band. Results Both N75 and P100 latencies increased with the addition of each filter when compared to baseline. Additionally, each filter numerically reduced intra-session amplitude variability relative to baseline. There were no significant effects on either the mean VEP amplitude or alpha wave parameters. Conclusions The Intuitive Colorimeter filters significantly increased both N75 and P100 latencies, an effect which is primarily attributable (∼75%) to luminance, and in some cases, specific spectral effects (e.g., blue and red). VEP amplitude and alpha power were not significantly affected. These findings provide an important reference to which either amplitude or power changes in light-sensitive, younger clinical groups can be compared. PMID:26293969
Infiltration of forest fire and residential wood smoke: an evaluation of air cleaner effectiveness.
Barn, Prabjit; Larson, Timothy; Noullett, Melanie; Kennedy, Susan; Copes, Ray; Brauer, Michael
2008-09-01
Communities impacted by fine-particle air pollution (particles with an aerodynamic diameter less than 2.5 microm; PM(2.5)) from forest fires and residential wood burning require effective, evidence-based exposure-reduction strategies. Public health recommendations during smoke episodes typically include advising community members to remain indoors and the use of air cleaners, yet little information is available on the effectiveness of these measures. Our study attempted to address the following objectives: to measure indoor infiltration factor (F(inf)) of PM(2.5) from forest fires/wood smoke, to determine the effectiveness of high-efficiency particulate air (HEPA) filter air cleaners in reducing indoor PM(2.5), and to analyze the home determinants of F(inf) and air cleaner effectiveness (ACE). We collected indoor/outdoor 1-min PM(2.5) averages and 48-h outdoor PM(2.5) filter samples for 21 winter and 17 summer homes impacted by wood burning and forest fire smoke, respectively, during 2004-2005. A portable HEPA filter air cleaner was operated indoors with the filter removed for one of two sampling days. Particle F(inf) and ACE were calculated for each home using a recursive model. We found mean F(inf)+/-SD was 0.27+/-0.18 and 0.61+/-0.27 in winter (n=19) and summer (n=13), respectively, for days when HEPA filters were not used. Lower F(inf)+/-SD values of 0.10+/-0.08 and 0.19+/-0.20 were found on corresponding days when HEPA filters were in place. Mean+/-SD ACE ([F(inf) without filter-F(inf) with filter]/F(inf) without filter) in winter and summer were 55+/-38% and 65+/-35%, respectively. Number of windows and season predicted F(inf) (P<0.001). No significant predictors of ACE were identified. Our findings show that remaining indoors combined with use of air cleaner can effectively reduce PM(2.5) exposure during forest fires and residential wood burning.
Effect of Intake Air Filter Condition on Light-Duty Gasoline Vehicles
DOE Office of Scientific and Technical Information (OSTI.GOV)
Thomas, John F; Huff, Shean P; West, Brian H
2012-01-01
Proper maintenance can help vehicles perform as designed, positively affecting fuel economy, emissions, and the overall drivability. This effort investigates the effect of one maintenance factor, intake air filter replacement, with primary focus on vehicle fuel economy, but also examining emissions and performance. Older studies, dealing with carbureted gasoline vehicles, have indicated that replacing a clogged or dirty air filter can improve vehicle fuel economy and conversely that a dirty air filter can be significantly detrimental to fuel economy. The effect of clogged air filters on the fuel economy, acceleration and emissions of five gasoline fueled vehicles is examined. Fourmore » of these were modern vehicles, featuring closed-loop control and ranging in model year from 2003 to 2007. Three vehicles were powered by naturally aspirated, port fuel injection (PFI) engines of differing size and cylinder configuration: an inline 4, a V6 and a V8. A turbocharged inline 4-cylinder gasoline direct injection (GDI) engine powered vehicle was the fourth modern gasoline vehicle tested. A vintage 1972 vehicle equipped with a carburetor (open-loop control) was also examined. Results reveal insignificant fuel economy and emissions sensitivity of modern vehicles to air filter condition, but measureable effects on the 1972 vehicle. All vehicles experienced a measured acceleration performance penalty with clogged intake air filters.« less
Resolution Enhancement In Ultrasonic Imaging By A Time-Varying Filter
NASA Astrophysics Data System (ADS)
Ching, N. H.; Rosenfeld, D.; Braun, M.
1987-09-01
The study reported here investigates the use of a time-varying filter to compensate for the spreading of ultrasonic pulses due to the frequency dependence of attenuation by tissues. The effect of this pulse spreading is to degrade progressively the axial resolution with increasing depth. The form of compensation required to correct for this effect is impossible to realize exactly. A novel time-varying filter utilizing a bank of bandpass filters is proposed as a realizable approximation of the required compensation. The performance of this filter is evaluated by means of a computer simulation. The limits of its application are discussed. Apart from improving the axial resolution, and hence the accuracy of axial measurements, the compensating filter could be used in implementing tissue characterization algorithms based on attenuation data.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bache, C.A.; Lisk, D.J.; Shane, B.S.
The effectiveness of filter tips for reducing cadmium, tar, nicotine, carbon monoxide and carbon dioxide in cigarettes was studied. The cigarettes were made from tobacco grown on municipal sewage sludge-amended soil and were therefore high in cadmium. When machine-smoked, filter tips did not result in a significant reduction of cadmium deposited on Cambridge filters. This may indicate that a considerable fraction of cadmium is present in the vapor phase of the smoke and therefore not reduced to the same extent as the tar by certain filters. Nicotine and carbon monoxide were reduced to a lesser extent than tar. This indicatesmore » that the filter tip has influenced the combustion of the tobacco column during smoking.« less
Factors Affecting the Levels of Heavy Metals in Juices Processed with Filter Aids.
Wang, Zhengfang; Jackson, Lauren S; Jablonski, Joseph E
2017-06-01
This study investigated factors that may contribute to the presence of arsenic and other heavy metals in apple and grape juices processed with filter aids. Different types and grades of filter aids were analyzed for arsenic, lead, and cadmium with inductively coupled plasma-tandem mass spectrometry. Potential factors affecting the transfer of heavy metals to juices during filtration treatments were evaluated. Effects of washing treatments on removal of heavy metals from filter aids were also determined. Results showed that diatomaceous earth (DE) generally contained a higher level of arsenic than perlite, whereas perlite had a higher lead content than DE. Cellulose contained the lowest level of arsenic among the surveyed filter aids. All samples of food-grade filter aids contained arsenic and lead levels that were below the U.S. Pharmacopeia and National Formulary limits of 10 ppm of total leachable arsenic and lead for food-grade DE filter aids. Two samples of arsenic-rich (>3 ppm) food-grade filter aids raised the level of arsenic in apple and grape juices during laboratory-scale filtration treatments, whereas three samples of low-arsenic (<1 ppm) food-grade filter aids did not affect arsenic levels in filtered juices. Filtration tests with simulated juices (pH 2.9 to 4.1, Brix [°Bx] 8.2 to 18.1, total suspended solids [TSS] 0.1 to 0.5%) showed that pH or sugar content had no effect on arsenic levels of filtered juices, whereas arsenic content of filtered juice was elevated when higher amounts of filter aid were used for filtration. Authentic unfiltered apple juice (pH 3.6, °Bx 12.9, TSS 0.4%) and grape juice (pH 3.3, °Bx 16.2, TSS 0.05%) were used to verify results obtained with simulated juices. However, body feed ratio did not affect the arsenic content of filtered authentic juices. Washing treatments were effective at reducing arsenic, but not cadmium or lead, concentrations in a DE filter aid. This study identified ways to reduce the amount of arsenic transferred to juices during filtration.
Silkwood, Justin D; Matthews, Kenneth L; Shikhaliev, Polad M
2013-05-01
Photon counting spectral (PCS) computed tomography (CT) shows promise for breast imaging. An issue with current photon-counting detectors is low count rate capabilities, artifacts resulting from nonuniform count rate across the field of view, and suboptimal spectral information. These issues are addressed in part by using tissue-equivalent adaptive filtration of the x-ray beam. The purpose of the study was to investigate the effect of adaptive filtration on different aspects of PCS breast CT. The theoretical formulation for the filter shape was derived for different filter materials and evaluated by simulation and an experimental prototype of the filter was fabricated from a tissue-like material (acrylic). The PCS CT images of a glandular breast phantom with adipose and iodine contrast elements were simulated at 40, 60, 90, and 120 kVp tube voltages, with and without adaptive filter. The CT numbers, CT noise, and contrast-to-noise ratio (CNR) were compared for spectral CT images acquired with and without adaptive filters. Similar comparison was made for material-decomposed PCS CT images. The adaptive filter improved the uniformity of CT numbers, CT noise, and CNR in both ordinary and material decomposed PCS CT images. At the same tube output the average CT noise with adaptive filter, although uniform, was higher than the average noise without adaptive filter due to x-ray absorption by the filter. Increasing tube output, so that average skin exposure with the adaptive filter was same as without filter, made the noise with adaptive filter comparable to or lower than that without adaptive filter. Similar effects were observed when energy weighting was applied, and when material decompositions were performed using energy selective CT data. An adaptive filter decreases count rate requirements to the photon counting detectors which enables PCS breast CT based on commercially available detector technologies. Adaptive filter also improves image quality in PCS breast CT by decreasing beam hardening artifacts and by eliminating spatial nonuniformities of CT numbers, noise, and CNR.
Numerical studies on the performance of an aerosol respirator with faceseal leakage
NASA Astrophysics Data System (ADS)
Zaripov, S. K.; Mukhametzanov, I. T.; Grinshpun, S. A.
2016-11-01
We studied the efficiency of a facepiece filtering respirator (FFR) in presence of a measurable faceseal leakage using the previously developed model of a spherical sampler with porous layer. In our earlier study, the model was validated for a specific filter permeability value. In this follow-up study, we investigated the effect of permeability on the overall respirator performance accounting for the faceseal leakage. The Total Inward Leakage (TIL) was calculated as a function of the leakage-to-filter surface ratio and the particle diameter. A good correlation was found between the theoretical and experimental TIL values. The TIL value was shown to increase and the effect of particle size on TIL to decrease as the leakage-to- filter surface ratio grows. The model confirmed that within the most penetrating particle size range (∼50 nm) and at relatively low leakage-to-filter surface ratios, an FFR performs better (TIL is lower) when the filter has a lower permeability which should be anticipated as long as the flow through the filter represents the dominant particle penetration pathway. An increase in leak size causes the TIL to rise; furthermore, under certain leakage-to-filter surface ratios, TIL for ultrafine particles becomes essentially independent on the filter properties due to a greater contribution of the aerosol flow through the faceseal leakage. In contrast to the ultrafine fraction, the larger particles (e.g., 800 nm) entering a typical high- or medium-quality respirator filter are almost fully collected by the filter medium regardless of its permeability; at the same time, the fraction penetrated through the leakage appears to be permeability- dependent: higher permeability generally results in a lower pressure drop through the filter which increases the air flow through the filter at the expense of the leakage flow. The latter reduces the leakage effect thus improving the overall respiratory protection level. The findings of this study provide valuable information for developing new respirators with a predictable actual workplace protection factor.
42 CFR 84.87 - Compressed gas filters; minimum requirements.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 42 Public Health 1 2010-10-01 2010-10-01 false Compressed gas filters; minimum requirements. 84.87...-Contained Breathing Apparatus § 84.87 Compressed gas filters; minimum requirements. All self-contained breathing apparatus using compressed gas shall have a filter downstream of the gas source to effectively...
42 CFR 84.87 - Compressed gas filters; minimum requirements.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 42 Public Health 1 2013-10-01 2013-10-01 false Compressed gas filters; minimum requirements. 84.87...-Contained Breathing Apparatus § 84.87 Compressed gas filters; minimum requirements. All self-contained breathing apparatus using compressed gas shall have a filter downstream of the gas source to effectively...
42 CFR 84.87 - Compressed gas filters; minimum requirements.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 42 Public Health 1 2011-10-01 2011-10-01 false Compressed gas filters; minimum requirements. 84.87...-Contained Breathing Apparatus § 84.87 Compressed gas filters; minimum requirements. All self-contained breathing apparatus using compressed gas shall have a filter downstream of the gas source to effectively...
42 CFR 84.87 - Compressed gas filters; minimum requirements.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 42 Public Health 1 2012-10-01 2012-10-01 false Compressed gas filters; minimum requirements. 84.87...-Contained Breathing Apparatus § 84.87 Compressed gas filters; minimum requirements. All self-contained breathing apparatus using compressed gas shall have a filter downstream of the gas source to effectively...
42 CFR 84.87 - Compressed gas filters; minimum requirements.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 42 Public Health 1 2014-10-01 2014-10-01 false Compressed gas filters; minimum requirements. 84.87...-Contained Breathing Apparatus § 84.87 Compressed gas filters; minimum requirements. All self-contained breathing apparatus using compressed gas shall have a filter downstream of the gas source to effectively...
Boladale, Mapayi; Yetunde, Oladimeji; Adesanmi, Akinsulore; Olutayo, Aloba; Olanrewaju, Ibigbami
2015-01-01
Dating violence is a complex phenomenon, and researchers continue to examine a wide range of precursors and contributing factors. Evidence indicates that violent intimate partners may be more likely to have personality disorders and dependency and attachment problems compared with non-violent ones. The aim of the present study is to evaluate the interaction between the personality profiles, pattern of psychopathology, and dating violence among university students in Obafemi Awolowo University, Ile-Ife. The study utilized a cross-sectional survey design with a total of 400 students selected using a multistage sampling technique. They completed the Sociodemographic Data Schedule, the Conflict Tactic Scale (CTS), Eysenck Personality Questionnaire (EPQ), and the General Health Questionnaire (GHQ). Univariate analysis was used to determine the prevalence of dating violence, psychopathology, and personality traits, and these were expressed in percentages. Association at bivariate level was assessed using chi-square and at multivariate level using logistic regression and correlations as was appropriate depending on the type of variable. The age of the respondents ranged between 18 and 35 years (M = 21.44, SD = 2.99). The prevalence of dating violence in the previous 12 months was 34%, and the prevalence of psychopathology was 15%. In the logistic regression model constructed, it was found that the significant predictors of dating violence were the psychoticism and neuroticism personality traits, which were also found to be positive correlates of psychopathology. The magnitude of dating violence found in this study is comparable with those found in other countries of the world. This study found an association between dating violence and personality in the study population and also between certain personality traits and psychopathology. The personality profiles of students could affect their interpersonal relationships greatly, and this fact must feature in dating violence prevention programs. © The Author(s) 2014.
Bello, Bamidele M; Fatusi, Adesegun O; Adepoju, Oluwatomi E; Maina, Beatrice W; Kabiru, Caroline W; Sommer, Marni; Mmari, Kristin
2017-10-01
This qualitative study assesses the cross-cultural and intergenerational reactions of young adolescents and parents to puberty in Ile-Ife, Nigeria, and Nairobi, Kenya. Sixty-six boys and girls (aged 11-13 years) and their parents participated in narrative interviews conducted in English or local languages in two urban poor settings in Ile-Ife and Nairobi. All interviews were recorded, transcribed, translated, and uploaded into Atlas.ti software for coding and analysis. Reactions of parents and adolescents to puberty were similar across both sites, with few exceptions. Adolescents' reactions to bodily changes varied from anxiety to pride. Adolescents generally tend to desire greater privacy; trying to hide their developing bodies from others. Most female adolescents emphasized breast development as compared with menstruation as the mark for pubertal initiation, while males emphasized voice changes. Among some ethnic groups in Nairobi, parents and adolescents view male circumcision as the hallmark of adolescence. Parents in both sites reported that with pubertal changes, adolescents tend to become arrogant and engaged in sexual relationships. Parents' reported responses to puberty include: educating adolescents on bodily changes; counseling on sexual relationships; and, provision of sanitary towels to females. Parents' responses are generally focused more on daughters. Approaches used by mothers in educating adolescents varied from the provision of factual information to fear/scare tactics. Compared with their own generation, parents perceive that their own children achieve pubertal development earlier, receive more puberty-related education from mothers, and are more exposed to and influenced by media and information technologies. Adolescents' responses to their pubertal bodily changes include anxiety, shame, and pride. Adolescents desire greater privacy. Parents' reactions were broadly supportive of their children's pubertal transition, but mothers' communication approaches may sometimes be inappropriate in terms of using fear/scare tactics. Copyright © 2017 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.
Modeling for free surface flow with phase change and its application to fusion technology
NASA Astrophysics Data System (ADS)
Luo, Xiaoyong
The development of predictive capabilities for free surface flow with phase change is essential to evaluate liquid wall protection schemes for various fusion chambers. With inertial fusion energy (IFE) concepts such as HYLIFE-II, rapid condensation into cold liquid surfaces is required when using liquid curtains for protecting reactor walls from blasts and intense neutron radiation. With magnetic fusion energy (MFE) concepts, droplets are injected onto the free surface of the liquid to minimize evaporation by minimizing the surface temperature. This dissertation presents a numerical methodology for free surface flow with phase change to help resolve feasibility issues encountered in the aforementioned fusion engineering fields, especially spray droplet condensation efficiency in IFE and droplet heat transfer enhancement on free surface liquid divertors in MFE. The numerical methodology is being conducted within the framework of the incompressible flow with the phase change model. A new second-order projection method is presented in conjunction with Approximate-Factorization techniques (AF method) for incompressible Navier-Stokes equations. A sub-cell conception is introduced and the Ghost Fluid Method in extended in a modified mass transfer model to accurately calculate the mass transfer across the interface. The Crank-Nicholson method is used for the diffusion term to eliminate the numerical viscous stability restriction. The third-order ENO scheme is used for the convective term to guarantee the accuracy of the method. The level set method is used to capture accurately the free surface of the flow and the deformation of the droplets. This numerical investigation identifies the physics characterizing transient heat and mass transfer of the droplet and the free surface flow. The results show that the numerical methodology is quite successful in modeling the free surface with phase change even though some severe deformations such as breaking and merging occur. The versatility of the numerical methodology shows that the work can easily handle complex physical conditions that occur in the fusion science and engineering.
Co-endemicity of loiasis and onchocerciasis in rain forest communities in southwestern Nigeria.
Ojurongbe, Olusola; Akindele, Akeem Abiodun; Adeleke, Monsuru Adebayo; Oyedeji, Matthew Oyebode; Adedokun, Samuel Adeyinka; Ojo, Josephine Folashade; Akinleye, Callistus Adewale; Bolaji, Oloyede Samuel; Adefioye, Olusegun Adelowo; Adeyeba, Oluwaseyi Adegboyega
2015-03-01
Loiasis is currently receiving attention as a disease of public health importance because of the possibility of increased risk of developing neurologic serious adverse event following mass ivermectin treatment against onchocerciasis in individual co-infected with Onchocerca volvulus and Loa loa. Rapid assessment procedure for loiasis (RAPLOA) was conducted in 12 communities covering the 3 senatorial districts of Osun State, Nigeria. A total of 960 people were interviewed for history of eye worm using the WHO guidelines for rapid assessment. The survey confirmed the presence of loiasis in all the 12 communities with 4 in Osun East/Ife south senatorial district being at high risk with a prevalence of over 40%. Based on the RAPLOA results, communities within Osun East/Ife south senatorial district were selected for microfilaraemic assessment of L. loa and O. volvulus. A total of 1115 and 1091 individuals were screened for L. loa and O. volvulus microfilaria worms respectively. 160 (14.3%) had L. loa microfilaria detected in their blood with 8 (5.0%) individuals having L. loa loads above 8000 mf/ml. 166 (15.2%) subjects had O. volvulus microfilaria (range 4-504 mf/ml) detected in their skin snip. 30 (2.69%) subjects were co-infected with both L. loa and O. volvulus. There was a significant variation in the prevalence (2.1% to 33.3%) of onchocerciasis in the communities studied (p = 0.001). Five (41.7%) of the studied communities had a prevalence that is equal to or greater than 20%. Low prevalence of onchocerciasis and loiasis co-infection in this study suggests that loiasis may not pose a serious epidemiological threat to the continuous distribution and sustainability of ivermectin for the treatment of onchocerciasis. Evaluation of the interruption of onchocerciasis transmissions in this region using all the indicators set forth by WHO is therefore suggested.
NASA Astrophysics Data System (ADS)
Gerst, M.; Cox, M. E.; Laser, M.; Locke, K. A.; Kapuscinski, A. R.
2017-12-01
Policy- and decision-making at the food-energy-water (FEW) nexus entails additional complexities due to the multi-objective nature of FEW socio-technical systems: policies and decisions meant to improve one facet of the nexus might be less beneficial, or even detrimental, to achieving goals for other facets. In addition, implementing policies and decisions may be more difficult due to increasing coordination required among stakeholders across each nexus facet. We highlight these issues in an economic, material/energy flow, and institutional assessment of dairy farms that produce power from anaerobic digestion of cow manure. This socio-technical system is an example of an integrated food-energy system (IFES), which co-produces food and energy. In the case of dairy farms, water is also a significant consideration because cow manure, if improperly managed, can negatively impact water bodies. Our assessment asks the questions (i) of whether or not adopting an IFES improves farm resilience under potential economic and environment futures and (ii) how decisions, policies, and information can best be tailored to the FEW nexus. Our study consists of semi-structured interviews of 60 farms split between the US states of New York and Vermont, both of which have enacted policies to encourage digester adoption. Each interview asks farmers about their material and energy flows, costs, and decision-making process for adopting (or not) an anaerobic digester. In addition, farmers are asked questions about challenges and barriers they might have faced and future drivers of change. Preliminary results highlight important interactions between policy and decision-making. Foremost, an analysis of policy cohesion shows that environmental objectives cross sectors and governance levels, as state-level greenhouse gas mitigation policies interact with federal-level nutrient management policies. This form of potential policy incoherence may introduce additional problems that hinder digester adoption and operation because technology options might be constrained and information needs may be too great for farmer's to consider adopting a digester.
UV Filters, Ingredients with a Recognized Anti-Inflammatory Effect
Couteau, Céline; Chauvet, Catherine; Paparis, Eva; Coiffard, Laurence
2012-01-01
Background To explain observed differences during SPF determination using either an in vivo or in vitro method, we hypothesized on the presence of ingredients having anti-inflammatory properties. Methodology/Principal Findings To research our hypothesis, we studied the 21 UV filters both available on the market and authorized by European regulations and subjected these filters to the phorbol-myristate-acetate test using mice. We then catalogued the 13 filters demonstrating a significant anti-inflammatory effect with edema inhibition percentages of more than 70%. The filters are: diethylhexyl butamido triazone (92%), benzophenone-5 and titanium dioxide (90%), benzophenone-3 (83%), octocrylène and isoamyl p-methoxycinnamate (82%), PEG-25 PABA and homosalate (80%), octyl triazone and phenylbenzimidazole sulfonic acid (78%), octyl dimethyl PABA (75%), bis-ethylhexyloxyphenol methoxyphenyl triazine and diethylamino hydroxybenzoyl hexylbenzoate (70%). These filters were tested at various concentrations, including their maximum authorized dose. We detected a dose-response relationship. Conclusions/Significance The anti-inflammatory effect of a sunscreen ingredient may affect the in vivo SPF value. PMID:23284607
DOE Office of Scientific and Technical Information (OSTI.GOV)
De Diego, J. A.; De Leo, M. A.; Cepa, J.
Lyα emitter (LAE) surveys have successfully used the excess in a narrowband filter compared to a nearby broadband image to find candidates. However, the odd spectral energy distribution (SED) of LAEs combined with the instrumental profile has important effects on the properties of the candidate samples extracted from these surveys. We investigate the effect of the bandpass width and the transmission profile of the narrowband filters used for extracting LAE candidates at redshifts z ≅ 6.5 through Monte Carlo simulations, and we present pilot observations to test the performance of tunable filters to find LAEs and other emission-line candidates. Wemore » compare the samples obtained using a narrow ideal rectangular filter, the Subaru NB921 narrowband filter, and sweeping across a wavelength range using the ultra-narrow-band tunable filters of the instrument OSIRIS, installed at the 10.4 m Gran Telescopio Canarias. We use this instrument for extracting LAE candidates from a small set of real observations. Broadband data from the Subaru, Hubble Space Telescope, and Spitzer databases were used for fitting SEDs to calculate photometric redshifts and to identify interlopers. Narrowband surveys are very efficient in finding LAEs in large sky areas, but the samples obtained are not evenly distributed in redshift along the filter bandpass, and the number of LAEs with equivalent widths <60 Å can be underestimated. These biased results do not appear in samples obtained using ultra-narrow-band tunable filters. However, the field size of tunable filters is restricted because of the variation of the effective wavelength across the image. Thus, narrowband and ultra-narrow-band surveys are complementary strategies to investigate high-redshift LAEs.« less
The intractable cigarette 'filter problem'.
Harris, Bradford
2011-05-01
When lung cancer fears emerged in the 1950s, cigarette companies initiated a shift in cigarette design from unfiltered to filtered cigarettes. Both the ineffectiveness of cigarette filters and the tobacco industry's misleading marketing of the benefits of filtered cigarettes have been well documented. However, during the 1950s and 1960s, American cigarette companies spent millions of dollars to solve what the industry identified as the 'filter problem'. These extensive filter research and development efforts suggest a phase of genuine optimism among cigarette designers that cigarette filters could be engineered to mitigate the health hazards of smoking. This paper explores the early history of cigarette filter research and development in order to elucidate why and when seemingly sincere filter engineering efforts devolved into manipulations in cigarette design to sustain cigarette marketing and mitigate consumers' concerns about the health consequences of smoking. Relevant word and phrase searches were conducted in the Legacy Tobacco Documents Library online database, Google Patents, and media and medical databases including ProQuest, JSTOR, Medline and PubMed. 13 tobacco industry documents were identified that track prominent developments involved in what the industry referred to as the 'filter problem'. These reveal a period of intense focus on the 'filter problem' that persisted from the mid-1950s to the mid-1960s, featuring collaborations between cigarette producers and large American chemical and textile companies to develop effective filters. In addition, the documents reveal how cigarette filter researchers' growing scientific knowledge of smoke chemistry led to increasing recognition that filters were unlikely to offer significant health protection. One of the primary concerns of cigarette producers was to design cigarette filters that could be economically incorporated into the massive scale of cigarette production. The synthetic plastic cellulose acetate became the fundamental cigarette filter material. By the mid-1960s, the meaning of the phrase 'filter problem' changed, such that the effort to develop effective filters became a campaign to market cigarette designs that would sustain the myth of cigarette filter efficacy. This study indicates that cigarette designers at Philip Morris, British-American Tobacco, Lorillard and other companies believed for a time that they might be able to reduce some of the most dangerous substances in mainstream smoke through advanced engineering of filter tips. In their attempts to accomplish this, they developed the now ubiquitous cellulose acetate cigarette filter. By the mid-1960s cigarette designers realised that the intractability of the 'filter problem' derived from a simple fact: that which is harmful in mainstream smoke and that which provides the smoker with 'satisfaction' are essentially one and the same. Only in the wake of this realisation did the agenda of cigarette designers appear to transition away from mitigating the health hazards of smoking and towards the perpetuation of the notion that cigarette filters are effective in reducing these hazards. Filters became a marketing tool, designed to keep and recruit smokers as consumers of these hazardous products.
Change in filter strip performance over ten years
M.G. Dosskey; K.D. Hoagland; J.R. Brandle
2007-01-01
Effectiveness of filter strips may change over a period of years because key soil and vegetation conditions change after conversion of cultivated farmland to permanent vegetation. the main objectives of this study were to : 1) determine if effectiveness of a filter strip changes over years since establishment, and 2) determine if temporal change depends on vegetation...
The Effectiveness of Irlen Filters for Improving Reading Performance: A Pilot Study.
ERIC Educational Resources Information Center
Blaskey, Penni; And Others
1990-01-01
The study compared the effectiveness of Irlen filters and traditional optometric intervention with 30 volunteers (ages 9-51). Pre- and posttesting revealed that subjects in both treatment groups were more comfortable after treatment, that only the vision therapy group showed improved visual functioning, and that the Irlen filter group did not show…
DOE Office of Scientific and Technical Information (OSTI.GOV)
Cui, Li-Ling; School of Science, Hunan University of Technology, Zhuzhou 412007; Yang, Bing-Chu, E-mail: bingchuyang@csu.edu.cn
2014-07-21
Spin-dependent transport properties of nanodevices constructed by iron-phthalocyanine (FePc) molecule sandwiched between two zigzag graphene nanoribbon electrodes are studied using first-principles quantum transport calculations. The effects of the symmetry and spin configuration of electrodes have been taken into account. It is found that large magnetoresistance, large spin polarization, dual spin-filtering, and negative differential resistance (NDR) can coexist in these devices. Our results show that 5Z-FePc system presents well conductive ability in both parallel (P) and anti-parallel (AP) configurations. For 6Z-FePc-P system, spin filtering effect and large spin polarization can be found. A dual spin filtering and NDR can also bemore » shown in 6Z-FePc-AP. Our studies indicate that the dual spin filtering effect depends on the orbitals symmetry of the energy bands and spin mismatching of the electrodes. And all the effects would open up possibilities for their applications in spin-valve, spin-filter as well as effective spin diode devices.« less
Hwang, Gi Byoung; Lee, Jung Eun; Nho, Chu Won; Lee, Byung Uk; Lee, Seung Jae; Jung, Jae Hee; Bae, Gwi-Nam
2012-04-01
Bioaerosols have received social and scientific attention because they can be hazardous to human health. Recently, antimicrobial treatments using natural products have been used to improve indoor air quality (IAQ) since they are typically less toxic to humans compared to other antimicrobial substances such as silver, carbon nanotubes, and metal oxides. Few studies, however, have examined how environmental conditions such as the relative humidity (RH), surrounding temperature, and retention time of bacteria on filters affect the filtration and antimicrobial characteristics of a filter treated with such natural products. In this study, we investigated changes in the morphology of the natural nanoparticles, pressure drop, filtration efficiency, and the inactivation rate caused by the short-term effect of humid airflow on antimicrobial fiber filters. Nanoparticles of Sophora flavescens were deposited on the filter media surface using an aerosol process. We observed coalescence and morphological changes of the nanoparticles on fiber filters under humid conditions of an RH >50%. The level of coalescence in these nanoparticles increased with increasing RH. Filters exposed to an RH of 25% have a higher pressure drop than those exposed to an RH >50%. In an inactivation test against Staphylococcus epidermidis bacterial aerosol, the inactivation efficiency at an RH of 25% was higher than that at an RH of 57% or 82%. To effectively apply antimicrobial filters using natural products in the environment, one must characterize the filters under various environmental conditions. Thus, this study provides important information on the use of antimicrobial filters made of natural products. Copyright © 2012 Elsevier B.V. All rights reserved.
Method for reducing pressure drop through filters, and filter exhibiting reduced pressure drop
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sappok, Alexander; Wong, Victor
Methods for generating and applying coatings to filters with porous material in order to reduce large pressure drop increases as material accumulates in a filter, as well as the filter exhibiting reduced and/or more uniform pressure drop. The filter can be a diesel particulate trap for removing particulate matter such as soot from the exhaust of a diesel engine. Porous material such as ash is loaded on the surface of the substrate or filter walls, such as by coating, depositing, distributing or layering the porous material along the channel walls of the filter in an amount effective for minimizing ormore » preventing depth filtration during use of the filter. Efficient filtration at acceptable flow rates is achieved.« less
An Intrinsically Switchable Ladder-Type Ferroelectric BST-on-Si Composite FBAR Filter.
Lee, Seungku; Mortazawi, Amir
2016-03-01
This paper presents a ladder-type bulk acoustic wave (BAW) intrinsically switchable filter based on ferroelectric thin-film bulk acoustic resonators (FBARs). The switchable filter can be turned on and off by the application of an external bias voltage due to the electrostrictive effect in thin-film ferroelectrics. In this paper, Barium Strontium Titanate (BST) is used as the ferroelectric material. A systematic design approach for switchable ladder-type ferroelectric filters is provided based on required filter specifications. A switchable filter is implemented in the form of a BST-on-Si composite structure to control the effective electromechanical coupling coefficient of FBARs. As an experimental verification, a 2.5-stage intrinsically switchable BST-on-Si composite FBAR filter is designed, fabricated, and measured. Measurement results for a typical BST-on-Si composite FBAR show a resonator mechanical quality factor (Q(m)) of 971, as well as a (Q(m)) × f of 2423 GHz. The filter presented here provides a measured insertion loss of 7.8 dB, out-of-band rejection of 26 dB, and fractional bandwidth of 0.33% at 2.5827 GHz when the filter is in the on state at a dc bias of 40 V. In its off state, the filter exhibits an isolation of 31 dB.
Correction of ultrasonic wave aberration with a time delay and amplitude filter.
Måsøy, Svein-Erik; Johansen, Tonni F; Angelsen, Bjørn
2003-04-01
Two-dimensional simulations with propagation through two different heterogeneous human body wall models have been performed to analyze different correction filters for ultrasonic wave aberration due to forward wave propagation. The different models each produce most of the characteristic aberration effects such as phase aberration, relatively strong amplitude aberration, and waveform deformation. Simulations of wave propagation from a point source in the focus (60 mm) of a 20 mm transducer through the body wall models were performed. Center frequency of the pulse was 2.5 MHz. Corrections of the aberrations introduced by the two body wall models were evaluated with reference to the corrections obtained with the optimal filter: a generalized frequency-dependent phase and amplitude correction filter [Angelsen, Ultrasonic Imaging (Emantec, Norway, 2000), Vol. II]. Two correction filters were applied, a time delay filter, and a time delay and amplitude filter. Results showed that correction with a time delay filter produced substantial reduction of the aberration in both cases. A time delay and amplitude correction filter performed even better in both cases, and gave correction close to the ideal situation (no aberration). The results also indicated that the effect of the correction was very sensitive to the accuracy of the arrival time fluctuations estimate, i.e., the time delay correction filter.
Allen, Todd L; Carter, Jody L; Morris, Brad J; Harker, Colleen P; Stevens, Mark H
2005-06-01
Venous thromboembolic (VTE) disease remains a significant cause of morbidity for trauma patients because many patients have injuries that may preclude effective VTE prevention and treatment. Retrievable vena cava filters may prove beneficial in this subset of trauma patients. Trauma patients at risk for VTE were identified and managed by institutional protocol. Patients who required a vena cava filter were managed with a device that could be retrieved or left in situ. A retrospective review of medical records was used to identify the use, indications, and complications associated with a retrievable filter. Fifty-three retrievable filters were placed in 51 patients. Two of these patients received a second filter, and 1 received a filter in the superior vena cava. Thirty-two filters were placed prophylactically, whereas 21 were placed for demonstrated venous thromboembolism (VTE). Retrieval was successful in 24 of 25 attempts. Twenty-nine filters became permanent: 10 for continued contraindications to anticoagulation without known VTE, 12 for known VTE and continued contraindications to anticoagulation, 1 for technical reasons, and 6 because of patient death. There were no complications of bleeding, device migration or thrombosis, infection, or pulmonary embolism. A retrievable vena cava filter appears safe and effective for the prevention of pulmonary embolism in the high-risk trauma patient who cannot receive anticoagulation.
Comparison of sand-based water filters for point-of-use arsenic removal in China.
Smith, Kate; Li, Zhenyu; Chen, Bohan; Liang, Honggang; Zhang, Xinyi; Xu, Ruifei; Li, Zhilin; Dai, Huanfang; Wei, Caijie; Liu, Shuming
2017-02-01
Contamination of groundwater wells by arsenic is a major problem in China. This study compared arsenic removal efficiency of five sand-based point-of-use filters with the aim of selecting the most effective filter for use in a village in Shanxi province, where the main groundwater source had arsenic concentration >200 μg/L. A biosand filter, two arsenic biosand filters, a SONO-style filter and a version of the biosand filter with nails embedded in the sand were tested. The biosand filter with embedded nails was the most consistent and effective under the study conditions, likely due to increased contact time between water and nails and sustained corrosion. Effluent arsenic was below China's standard of 50 μg/L for more than six months after construction. The removal rate averaged 92% and was never below 86%. In comparison, arsenic removal for the nail-free biosand filter was never higher than 53% and declined with time. The arsenic biosand filter, in which nails sit in a diffuser basin above the sand, performed better but effluent arsenic almost always exceeded the standard. This highlights the positive impact on arsenic removal of embedding nails within the top layer of biosand filter sand and the promise of this low-cost filtration method for rural areas affected by arsenic contamination. Copyright © 2016 Elsevier Ltd. All rights reserved.
Effect of filters and reconstruction algorithms on I-124 PET in Siemens Inveon PET scanner
NASA Astrophysics Data System (ADS)
Ram Yu, A.; Kim, Jin Su
2015-10-01
Purpose: To assess the effects of filtering and reconstruction on Siemens I-124 PET data. Methods: A Siemens Inveon PET was used. Spatial resolution of I-124 was measured to a transverse offset of 50 mm from the center FBP, 2D ordered subset expectation maximization (OSEM2D), 3D re-projection algorithm (3DRP), and maximum a posteriori (MAP) methods were tested. Non-uniformity (NU), recovery coefficient (RC), and spillover ratio (SOR) parameterized image quality. Mini deluxe phantom data of I-124 was also assessed. Results: Volumetric resolution was 7.3 mm3 from the transverse FOV center when FBP reconstruction algorithms with ramp filter was used. MAP yielded minimal NU with β =1.5. OSEM2D yielded maximal RC. SOR was below 4% for FBP with ramp, Hamming, Hanning, or Shepp-Logan filters. Based on the mini deluxe phantom results, an FBP with Hanning or Parzen filters, or a 3DRP with Hanning filter yielded feasible I-124 PET data.Conclusions: Reconstruction algorithms and filters were compared. FBP with Hanning or Parzen filters, or 3DRP with Hanning filter yielded feasible data for quantifying I-124 PET.
In vitro assessment of six aspiration catheters using a distal protection filter.
Fujimura, Tatsuhiro; Okamura, Takayuki; Ando, Miyuki; Uchida, Kousuke; Tone, Takashi; Yonezawa, Fumio; Yano, Masafumi
2016-01-01
We assessed performance of 6 aspiration catheters for distal embolization using a distal protection filter in an in vitro experiment. In acute myocardial infarction, a distal protection filter is used for lesions likely to induce a distal embolism. Which aspiration cathether is most effective when used with a distal protection filter remains still unclear. A 0.5-cm3 bolus of gelatin as a model of stagnant pools of coronary plaque debris was captured in the distal protection filter and aspirated by 6 aspiration catheters. We measured and compared the length of the suspended embolus matter. Among the 6 catheters evaluated, the use of the Export Advance catheter (Medtronic) resulted in significantly shorter lengths of the suspended embolus matter compared to the use of the TVAC II (Nipro), Thrombuster III SL (Kaneka), and Rebirth Pro (Goodman) catheters (p < 0.01). The residual embolus matter in all cases had drained distally to the distal protection filter when the filter was retrieved. The use of the Export Advance catheter showed better performance using a distal protection filter in this in vitro experiment, and its use might be more effective in preventing distal embolisms in combination with a distal protection filter.
Speckle noise reduction in SAR images ship detection
NASA Astrophysics Data System (ADS)
Yuan, Ji; Wu, Bin; Yuan, Yuan; Huang, Qingqing; Chen, Jingbo; Ren, Lin
2012-09-01
At present, there are two types of method to detect ships in SAR images. One is a direct detection type, detecting ships directly. The other is an indirect detection type. That is, it firstly detects ship wakes, and then seeks ships around wakes. The two types all effect by speckle noise. In order to improve the accuracy of ship detection and get accurate ship and ship wakes parameters, such as ship length, ship width, ship area, the angle of ship wakes and ship outline from SAR images, it is extremely necessary to remove speckle noise in SAR images before data used in various SAR images ship detection. The use of speckle noise reduction filter depends on the specification for a particular application. Some common filters are widely used in speckle noise reduction, such as the mean filter, the median filter, the lee filter, the enhanced lee filter, the Kuan filter, the frost filter, the enhanced frost filter and gamma filter, but these filters represent some disadvantages in SAR image ship detection because of the various types of ship. Therefore, a mathematical function known as the wavelet transform and multi-resolution analysis were used to localize an SAR ocean image into different frequency components or useful subbands, and effectively reduce the speckle in the subbands according to the local statistics within the bands. Finally, the analysis of the statistical results are presented, which demonstrates the advantages and disadvantages of using wavelet shrinkage techniques over standard speckle filters.
NASA Technical Reports Server (NTRS)
Mckeown, Anderson B; Hibbard, Robert R
1955-01-01
The effect of dissolved oxygen in the filter-clogging characteristics of three JP-4 and two JP-5 fuels was studied at 300 degrees to 400 degrees F in a bench- scale rig, employing filter paper as the filter medium. The residence time of the fuel at the high temperature was approximately 6 seconds. For these conditions, the clogging characteristics of the fuels increased with both increasing temperature and increasing concentration of dissolved oxygen. The amount of insoluble material formed at high temperatures necessary to produce clogging of filters was very small, of the order of 1 milligram per gallon of fuel.
A 10-Gbit/s EML link using detuned narrowband optical filtering.
Ebrahimi, P; Jones, R; Wang, Y; Yan, L; Mader, T; Paniccia, M; Willner, A E; Paraschis, L
2007-08-20
In this paper, the effects of asymmetric narrowband optical filtering are investigated in a 10-Gbit/s optical communication link using integrated electro-absorption modulated lasers (EML). We investigate the effect of EML chirp on link performance as well as the optimal filter bandwidth and wavelength detuning. We show that both the phase response and the spectral narrowing of the filter will enable a longer distance transmission by interacting with the EML transient chirp and compensating for the fiber chromatic dispersion. Experimentally, an 8.75-GHz filter is shown to improve the link distance by 40 km from 65 to 105 km, when transmitting over standard single mode fiber.
Electric control of wave vector filtering in a hybrid magnetic-electric-barrier nanostructure
NASA Astrophysics Data System (ADS)
Kong, Yong-Hong; Lu, Ke-Yu; He, Ya-Ping; Liu, Xu-Hui; Fu, Xi; Li, Ai-Hua
2018-06-01
We theoretically investigate how to manipulate the wave vector filtering effect by a traverse electric field for electrons across a hybrid magnetic-electric-barrier nanostructure, which can be experimentally realized by depositing a ferromagnetic stripe and a Schottky-metal stripe on top and bottom of a GaAs/Al x Ga1- x As heterostructure, respectively. The wave vector filtering effect is found to be related closely to the applied electric field. Moreover, the wave vector filtering efficiency can be manipulated by changing direction or adjusting strength of the traverse electric field. Therefore, such a nanostructure can be employed as an electrically controllable electron-momentum filter for nanoelectronics applications.
Faculty Experiences of Internet Filtering at a Proprietary Higher Education Institution
ERIC Educational Resources Information Center
Rzemyk, Thomas J.
2011-01-01
Despite widespread acknowledgement that Internet access in libraries and schools is filtered, the effects of that filtering on faculty who must utilize such a system for research, teaching, and curriculum development in American higher education are not known. This qualitative case study explored faculty experiences of Internet filtering in terms…
NASA Technical Reports Server (NTRS)
1987-01-01
A compact, lightweight electrolytic water filter generates silver ions in concentrations of 50 to 100 parts per billion in the water flow system. Silver ions serve as effective bactericide/deodorizers. Ray Ward requested and received from NASA a technical information package on the Shuttle filter, and used it as basis for his own initial development, a home use filter.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kolb, T.E.; Skelly, J.M.; Steiner, K.C.
1993-06-01
Black cherry seedlings of two open-pollinated families were exposed to ambient ozone in open plots (100%) and plots receiving non-filtered (95%), half-filtered (60%) and full-filtered (40%) concentrations via open-top chambers between early June and late-September 1992 in a replicated field experiment in central Pennsylvania. Seasonal 24-hour ambient ozone concentration averaged 34 ppb with a peak 1-hour concentration of 110 ppb. Foliar symptoms of ozone damage (adaxial stipple) occurred most prominently in open and non-filtered plots and differed between families. Net photosynthetic rate for both families was significantly lower in open and non-filtered plots compared with half- and full-filtered plots onmore » most dates, while ozone concentration had no consistent effect on leaf conductance or dark respiration. Leaf conductance of the ozone sensitive family was significantly greater than the ozone tolerant family on most dates. First-year height and diameter growth were significantly lower in open and non-filtered plots compared with half- and full-filtered plots for both families.« less
Effects of antimicrobial treatment on fiberglass-acrylic filters.
Cecchini, C; Verdenelli, M C; Orpianesi, C; Dadea, G M; Cresci, A
2004-01-01
The aims of the present study were to: (i) analyse a group of antimicrobial agents and to select the most active against test microbial strains; (ii) test the effect of the antimicrobial treatment on air filters in order to reduce microbial colonization. Different kinds of antimicrobial agents were analysed to assess their compatibility with the production process of air filter media. The minimal inhibitory concentration for each antimicrobial agent was determined against a defined list of microbial strains, and an antimicrobial activity assay of filter prototypes was developed to determine the most active agent among the compatible antimicrobials. Then, the most active was chosen and added directly to the filter during the production process. The microbial colonization of treated and untreated filter media was assessed at different working times for different incubation times by stereomicroscope and scanning electron microscope analysis. Some of the antimicrobial agents analysed were more active against microbial test strains and compatible with the production process of the filter media. Filter sections analysis of treated filter media showed a significantly lower microbial colonization than those untreated, a reduction of species both in density and varieties and of the presence of bacteria and fungal hyphae with reproductive structures. This study demonstrated the ability of antimicrobial treatments to inhibit the growth of micro-organisms in filter media and subsequently to increase indoor air quality (IAQ), highlighting the value of adding antimicrobials to filter media. To make a contribution to solving the problem of microbial contamination of air filters, by demonstrating the efficacy of incorporating antimicrobial agents in the filter media to improve IAQ and health.
Safety and Effectiveness of the Denali Inferior Vena Cava Filter: Intermediate Follow-Up Results.
Reis, Stephen P; Kovoor, Jerry; Sutphin, Patrick D; Toomay, Seth; Trimmer, Clayton; Pillai, Anil; Reddick, Mark; Kalva, Sanjeeva P
2016-08-01
The purpose of the study is to evaluate the clinical safety and effectiveness of the Denali (Bard, Tempe, Arizona) retrievable inferior vena cava (IVC) filter. In this retrospective study, authors reviewed the data of Denali IVC filters placed at their institution between 2013 and 2015. The clinical presentation, indications, and procedure-related complications during placement and retrieval were evaluated. The frequency of post filter pulmonary embolism (PE) and filter-related complications was assessed. Denali filters were placed in 87 patients (47 males; mean age: 56 years). Twenty patients presented with PE, 45 with deep vein thrombosis (DVT), and 21 with both PE and DVT, 1 filter was placed prophylactically before surgery. Indications for filter placement included contraindications to anticoagulation (AC; n = 80), failure of AC (n = 4), and complications of AC (n = 3). No patients had PE on follow-up imaging after filter placement. Retrieval was attempted in 31 patients after a mean period of 125 days (range: 34-324 days). The filter was successfully removed in 31 (100%) patients. Follow-up imaging, available in 71 (82%) patients (range: 2-538 days), demonstrated penetration of 15 legs in 5 patients, caval thrombus in 3, 1 resulting in caval occlusion, <15° filter tilt in 5, and no leg fractures or crossed legs. The Denali filter is safe during deployment and readily retrievable. The overall safety following deployment is similar to those reported in the literature, and the incidence of filter fractures and migration appears to be less than the previous generation of Bard devices. © The Author(s) 2016.
Gregori, Josep; Villarreal, Laura; Sánchez, Alex; Baselga, José; Villanueva, Josep
2013-12-16
The microarray community has shown that the low reproducibility observed in gene expression-based biomarker discovery studies is partially due to relying solely on p-values to get the lists of differentially expressed genes. Their conclusions recommended complementing the p-value cutoff with the use of effect-size criteria. The aim of this work was to evaluate the influence of such an effect-size filter on spectral counting-based comparative proteomic analysis. The results proved that the filter increased the number of true positives and decreased the number of false positives and the false discovery rate of the dataset. These results were confirmed by simulation experiments where the effect size filter was used to evaluate systematically variable fractions of differentially expressed proteins. Our results suggest that relaxing the p-value cut-off followed by a post-test filter based on effect size and signal level thresholds can increase the reproducibility of statistical results obtained in comparative proteomic analysis. Based on our work, we recommend using a filter consisting of a minimum absolute log2 fold change of 0.8 and a minimum signal of 2-4 SpC on the most abundant condition for the general practice of comparative proteomics. The implementation of feature filtering approaches could improve proteomic biomarker discovery initiatives by increasing the reproducibility of the results obtained among independent laboratories and MS platforms. Quality control analysis of microarray-based gene expression studies pointed out that the low reproducibility observed in the lists of differentially expressed genes could be partially attributed to the fact that these lists are generated relying solely on p-values. Our study has established that the implementation of an effect size post-test filter improves the statistical results of spectral count-based quantitative proteomics. The results proved that the filter increased the number of true positives whereas decreased the false positives and the false discovery rate of the datasets. The results presented here prove that a post-test filter applying a reasonable effect size and signal level thresholds helps to increase the reproducibility of statistical results in comparative proteomic analysis. Furthermore, the implementation of feature filtering approaches could improve proteomic biomarker discovery initiatives by increasing the reproducibility of results obtained among independent laboratories and MS platforms. This article is part of a Special Issue entitled: Standardization and Quality Control in Proteomics. Copyright © 2013 Elsevier B.V. All rights reserved.
AIRTV: Broadband Direct to Aircraft
NASA Astrophysics Data System (ADS)
Sorbello, R.; Stone, R.; Bennett, S. B.; Bertenyi, E.
2002-01-01
Airlines have been continuously upgrading their wide-body, long-haul aircraft with IFE (in-flight entertainment) systems that can support from 12 to 24 channels of video entertainment as well as provide the infrastructure to enable in-seat delivery of email and internet services. This is a direct consequence of increased passenger demands for improved in-flight services along with the expectations that broadband delivery systems capable of providing live entertainment (news, sports, financial information, etc.) and high speed data delivery will soon be available. The recent events of Sept. 11 have slowed the airline's upgrade of their IFE systems, but have also highlighted the compelling need for broadband aeronautical delivery systems to include operational and safety information. Despite the impact of these events, it is estimated that by 2005 more than 3000 long haul aircraft (servicing approximately 1 billion passengers annually) will be fully equipped with modern IFE systems. Current aircraft data delivery systems, which use either Inmarsat or NATS, are lacking in bandwidth and consequently are unsuitable to satisfy passenger demands for broadband email/internet services or the airlines' burgeoning data requirements. Present live video delivery services are limited to regional coverage and are not readily expandable to global or multiregional service. Faced with a compelling market demand for high data transport to aircraft, AirTV has been developing a broadband delivery system that will meet both passengers' and airlines' needs. AirTV is a global content delivery system designed to provide a range of video programming and data services to commercial airlines. When AirTV is operational in 2004, it will provide a broadband connection directly to the aircraft, delivering live video entertainment, internet/email service and essential operational and safety data. The system has been designed to provide seamless global service to all airline routes except for those over the poles. The system consists of a constellation of 4 geostationary satellites covering the earth and delivering its signals to the aircraft at S band (2.52 -2.67 GHz). The S-band spectrum is ideal for this application since it is allocated on a primary basis by the ITU for global broadcast service. The AirTV service is expected to begin in 2004 and should be unencumbered by adjacent satellite interference due to near completion of the ITU coordination process. Each satellite will deliver four 20 Mbps QPSK data streams consisting of multiplexed compressed digital video channels and IP data over the full global beam coverage. The 80 Mbps capacity of each satellite will provide approximately 60 video channels while still allocating 40 Mbits to data services. The combined constellation capacity of 320 Mbits will significantly exceed the capacity of any similar existing or currently planned global satellite system. In addition, the simplicity of the 4-satellite approach is the most cost effective means to deliver high bandwidth globally. Return links, which are required for internet service, will be provided through the existing Inmarsat Aero-H system already onboard virtually all long haul aircraft and will provide return data rates from the aircraft as high as 432 kbps. integrated receiver/decoder (IRD) assembly. The phased array antenna, a key technology element, is being developed by AirTV's strategic partner, CMC Electronics. This antenna is a scaled version of CMC's Inmarsat Aero H antenna and is capable of scanning to 5 degrees above the horizon. Wide angle scanning up to 85 degrees from zenith is necessary for aircraft traversing the northernmost latitudes on transoceanic routes. AirTV has designed both the satellite coverage and aircraft antenna performance to ensure that high signal quality is maintained along all non-polar airline routes. AirTV will be the future of aeronautical broadband delivery. It has been designed specifically for global services and uses the ideal spectrum for this application. It will revolutionize the delivery of content to aircraft. This paper will describe the AirTV system and highlight its advanced service capabilities.
Widely tunable erbium-doped fiber laser based on multimode interference effect.
Castillo-Guzman, A; Antonio-Lopez, J E; Selvas-Aguilar, R; May-Arrioja, D A; Estudillo-Ayala, J; LiKamWa, P
2010-01-18
A widely tunable erbium-doped all-fiber laser has been demonstrated. The tunable mechanism is based on a novel tunable filter using multimode interference effects (MMI). The tunable MMI filter was applied to fabricate a tunable erbium-doped fiber laser via a standard ring cavity. A tuning range of 60 nm was obtained, ranging from 1549 nm to 1609 nm, with a signal to noise ratio of 40 dB. The tunable MMI filter mechanism is very simple and inexpensive, but also quite efficient as a wavelength tunable filter.
Identifying and mitigating batch effects in whole genome sequencing data.
Tom, Jennifer A; Reeder, Jens; Forrest, William F; Graham, Robert R; Hunkapiller, Julie; Behrens, Timothy W; Bhangale, Tushar R
2017-07-24
Large sample sets of whole genome sequencing with deep coverage are being generated, however assembling datasets from different sources inevitably introduces batch effects. These batch effects are not well understood and can be due to changes in the sequencing protocol or bioinformatics tools used to process the data. No systematic algorithms or heuristics exist to detect and filter batch effects or remove associations impacted by batch effects in whole genome sequencing data. We describe key quality metrics, provide a freely available software package to compute them, and demonstrate that identification of batch effects is aided by principal components analysis of these metrics. To mitigate batch effects, we developed new site-specific filters that identified and removed variants that falsely associated with the phenotype due to batch effect. These include filtering based on: a haplotype based genotype correction, a differential genotype quality test, and removing sites with missing genotype rate greater than 30% after setting genotypes with quality scores less than 20 to missing. This method removed 96.1% of unconfirmed genome-wide significant SNP associations and 97.6% of unconfirmed genome-wide significant indel associations. We performed analyses to demonstrate that: 1) These filters impacted variants known to be disease associated as 2 out of 16 confirmed associations in an AMD candidate SNP analysis were filtered, representing a reduction in power of 12.5%, 2) In the absence of batch effects, these filters removed only a small proportion of variants across the genome (type I error rate of 3%), and 3) in an independent dataset, the method removed 90.2% of unconfirmed genome-wide SNP associations and 89.8% of unconfirmed genome-wide indel associations. Researchers currently do not have effective tools to identify and mitigate batch effects in whole genome sequencing data. We developed and validated methods and filters to address this deficiency.
Presser, Cary; Nazarian, Ashot; Conny, Joseph M.; Chand, Duli; Sedlacek, Arthur; Hubbe, John M.
2017-01-01
Absorptivity measurements with a laser-heating approach, referred to as the laser-driven thermal reactor (LDTR), were carried out in the infrared and applied at ambient (laboratory) non-reacting conditions to particle-laden filters from a three-wavelength (visible) particle/soot absorption photometer (PSAP). The particles were obtained during the Biomass Burning Observation Project (BBOP) field campaign. The focus of this study was to determine the particle absorption coefficient from field-campaign filter samples using the LDTR approach, and compare results with other commercially available instrumentation (in this case with the PSAP, which has been compared with numerous other optical techniques). Advantages of the LDTR approach include 1) direct estimation of material absorption from temperature measurements (as opposed to resolving the difference between the measured reflection/scattering and transmission), 2) information on the filter optical properties, and 3) identification of the filter material effects on particle absorption (e.g., leading to particle absorption enhancement or shadowing). For measurements carried out under ambient conditions, the particle absorptivity is obtained with a thermocouple placed flush with the filter back surface and the laser probe beam impinging normal to the filter particle-laden surface. Thus, in principle one can employ a simple experimental arrangement to measure simultaneously both the transmissivity and absorptivity (at different discrete wavelengths) and ascertain the particle absorption coefficient. For this investigation, LDTR measurements were carried out with PSAP filters (pairs with both blank and exposed filters) from eight different days during the campaign, having relatively light but different particle loadings. The observed particles coating the filters were found to be carbonaceous (having broadband absorption characteristics). The LDTR absorption coefficient compared well with results from the PSAP. The analysis was also expanded to account for the filter fiber scattering on particle absorption in assessing particle absorption enhancement and shadowing effects. The results indicated that absorption enhancement effects were significant, and diminished with increased filter particle loading. PMID:28690360
Presser, Cary; Nazarian, Ashot; Conny, Joseph M; Chand, Duli; Sedlacek, Arthur; Hubbe, John M
2017-01-01
Absorptivity measurements with a laser-heating approach, referred to as the laser-driven thermal reactor (LDTR), were carried out in the infrared and applied at ambient (laboratory) non-reacting conditions to particle-laden filters from a three-wavelength (visible) particle/soot absorption photometer (PSAP). The particles were obtained during the Biomass Burning Observation Project (BBOP) field campaign. The focus of this study was to determine the particle absorption coefficient from field-campaign filter samples using the LDTR approach, and compare results with other commercially available instrumentation (in this case with the PSAP, which has been compared with numerous other optical techniques). Advantages of the LDTR approach include 1) direct estimation of material absorption from temperature measurements (as opposed to resolving the difference between the measured reflection/scattering and transmission), 2) information on the filter optical properties, and 3) identification of the filter material effects on particle absorption (e.g., leading to particle absorption enhancement or shadowing). For measurements carried out under ambient conditions, the particle absorptivity is obtained with a thermocouple placed flush with the filter back surface and the laser probe beam impinging normal to the filter particle-laden surface. Thus, in principle one can employ a simple experimental arrangement to measure simultaneously both the transmissivity and absorptivity (at different discrete wavelengths) and ascertain the particle absorption coefficient. For this investigation, LDTR measurements were carried out with PSAP filters (pairs with both blank and exposed filters) from eight different days during the campaign, having relatively light but different particle loadings. The observed particles coating the filters were found to be carbonaceous (having broadband absorption characteristics). The LDTR absorption coefficient compared well with results from the PSAP. The analysis was also expanded to account for the filter fiber scattering on particle absorption in assessing particle absorption enhancement and shadowing effects. The results indicated that absorption enhancement effects were significant, and diminished with increased filter particle loading.
Su, Wen-jin; Wang, Li-min; Weng, Shao-fan; Wang, Hai-jiao; Du, Li-li; Liu, Yue-wei; Yang, Lei; Chen, Wei-hong
2008-04-01
To assess the effects of the alteration of humidity and (or) temperature on weight of filters without and with ambient particulate matter in a balance room. The mass of blank dust sampling filters were weighed under (18 +/- 1) degrees C and (28 +/- 1) degrees C respectively, with the humidity varying from 35% relative humidity (RH) to 100% RH in a balance room. Then the blank filters were divided into two groups and were used to sample total dust and respirable dust. After sampling, the loaded filters were re-weighed under above conditions and the mass difference before and after the sampling were compared and analyzed. The vibration of the average mass of filters varied from 0.10 to 0.13 mg and from 0.06 to 0.09 mg under the temperatures of (18 +/- 1) degrees C and (28 +/- 1) degrees C respectively; When both the temperature and humidity changed, it varied from 0.12 to 0.16 mg. The deviation of average mass difference ranged from 0.07 to 0.10 mg and from 0.04 to 0.08 mg under the two temperatures mentioned above; When both the temperature and humidity changed, it varied from 0.09 to 0.14 mg. The average mass of blank filters and loaded filters were all positively correlated with the change of humidity (P < 0.01). No effects of humidity on the average mass difference of the loaded filters were observed. The average mass differences of loaded filters and blank filters under (18 +/- 1) degrees C were significantly higher than that under (28 +/- 1) degrees C (P < 0.01) when humidity was not changed. The alteration of humidity and (or) temperature in a balance room attributes to the deviation of the measurement of the mass of filters and thus affects the gravimetric measurements of ambient particulate matter.
Monte-Carlo modelling to determine optimum filter choices for sub-microsecond optical pyrometry.
Ota, Thomas A; Chapman, David J; Eakins, Daniel E
2017-04-01
When designing a spectral-band pyrometer for use at high time resolutions (sub-μs), there is ambiguity regarding the optimum characteristics for a spectral filter(s). In particular, while prior work has discussed uncertainties in spectral-band pyrometry, there has been little discussion of the effects of noise which is an important consideration in time-resolved, high speed experiments. Using a Monte-Carlo process to simulate the effects of noise, a model of collection from a black body has been developed to give insights into the optimum choices for centre wavelength and passband width. The model was validated and then used to explore the effects of centre wavelength and passband width on measurement uncertainty. This reveals a transition centre wavelength below which uncertainties in calculated temperature are high. To further investigate system performance, simultaneous variation of the centre wavelength and bandpass width of a filter is investigated. Using data reduction, the effects of temperature and noise levels are illustrated and an empirical approximation is determined. The results presented show that filter choice can significantly affect instrument performance and, while best practice requires detailed modelling to achieve optimal performance, the expression presented can be used to aid filter selection.
Choi, Dong Yun; An, Eun Jeong; Jung, Soo-Ho; Song, Dong Keun; Oh, Yong Suk; Lee, Hyung Woo; Lee, Hye Moon
2018-04-10
Through the direct decomposition of an Al precursor ink AlH 3 {O(C 4 H 9 ) 2 }, we fabricated an Al-coated conductive fiber filter for the efficient electrostatic removal of airborne particles (>99%) with a low pressure drop (~several Pascals). The effects of the electrical and structural properties of the filters were investigated in terms of collection efficiency, pressure drop, and particle deposition behavior. The collection efficiency did not show a significant correlation with the extent of electrical conductivity, as the filter is electrostatically charged by the metallic Al layers forming electrical networks throughout the fibers. Most of the charged particles were collected via surface filtration by Coulombic interactions; consequently, the filter thickness had little effect on the collection efficiency. Based on simulations of various fiber structures, we found that surface filtration can transition to depth filtration depending on the extent of interfiber distance. Therefore, the effects of structural characteristics on collection efficiency varied depending on the degree of the fiber packing density. This study will offer valuable information pertaining to the development of a conductive metal/polymer composite air filter for an energy-efficient and high-performance electrostatic filtration system.
Spatial optical crosstalk in CMOS image sensors integrated with plasmonic color filters.
Yu, Yan; Chen, Qin; Wen, Long; Hu, Xin; Zhang, Hui-Fang
2015-08-24
Imaging resolution of complementary metal oxide semiconductor (CMOS) image sensor (CIS) keeps increasing to approximately 7k × 4k. As a result, the pixel size shrinks down to sub-2μm, which greatly increases the spatial optical crosstalk. Recently, plasmonic color filter was proposed as an alternative to conventional colorant pigmented ones. However, there is little work on its size effect and the spatial optical crosstalk in a model of CIS. By numerical simulation, we investigate the size effect of nanocross array plasmonic color filters and analyze the spatial optical crosstalk of each pixel in a Bayer array of a CIS with a pixel size of 1μm. It is found that the small pixel size deteriorates the filtering performance of nanocross color filters and induces substantial spatial color crosstalk. By integrating the plasmonic filters in the low Metal layer in standard CMOS process, the crosstalk reduces significantly, which is compatible to pigmented filters in a state-of-the-art backside illumination CIS.
Spatial filter with volume gratings for high-peak-power multistage laser amplifiers
NASA Astrophysics Data System (ADS)
Tan, Yi-zhou; Yang, Yi-sheng; Zheng, Guang-wei; Shen, Ben-jian; Pan, Heng-yue; Liu, Li
2010-08-01
The regular spatial filters comprised of lens and pinhole are essential component in high power laser systems, such as lasers for inertial confinement fusion, nonlinear optical technology and directed-energy weapon. On the other hand the pinhole is treated as a bottleneck of high power laser due to harmful plasma created by the focusing beam. In this paper we present a spatial filter based on angular selectivity of Bragg diffraction grating to avoid the harmful focusing effect in the traditional pinhole filter. A spatial filter consisted of volume phase gratings in two-pass amplifier cavity were reported. Two-dimensional filter was proposed by using single Pi-phase-shifted Bragg grating, numerical simulation results shown that its angular spectrum bandwidth can be less than 160urad. The angular selectivity of photo-thermorefractive glass and RUGATE film filters, construction stability, thermal stability and the effects of misalignments of gratings on the diffraction efficiencies under high-pulse-energy laser operating condition are discussed.
CUDA-based acceleration of collateral filtering in brain MR images
NASA Astrophysics Data System (ADS)
Li, Cheng-Yuan; Chang, Herng-Hua
2017-02-01
Image denoising is one of the fundamental and essential tasks within image processing. In medical imaging, finding an effective algorithm that can remove random noise in MR images is important. This paper proposes an effective noise reduction method for brain magnetic resonance (MR) images. Our approach is based on the collateral filter which is a more powerful method than the bilateral filter in many cases. However, the computation of the collateral filter algorithm is quite time-consuming. To solve this problem, we improved the collateral filter algorithm with parallel computing using GPU. We adopted CUDA, an application programming interface for GPU by NVIDIA, to accelerate the computation. Our experimental evaluation on an Intel Xeon CPU E5-2620 v3 2.40GHz with a NVIDIA Tesla K40c GPU indicated that the proposed implementation runs dramatically faster than the traditional collateral filter. We believe that the proposed framework has established a general blueprint for achieving fast and robust filtering in a wide variety of medical image denoising applications.
Takahashi, Shigetoshi; Hwang, In-Hee; Matsuto, Toshihiko
2016-06-01
Fabric filters are widely used to remove dust from flue gas generated by waste incineration. However, a pressure drop occurs at the filters, caused by growth of a dust layer on the filter fabric despite regular cleaning by pulsed-jet air. The pressure drop at the fabric filters leads to energy consumption at induced draft fan to keep the incinerator on negative pressure, so that its proper control is important to operate incineration facility efficiently. The pressure drop at fabric filters decreased whenever phosphoric acid wastewater (PAW) was sprayed into an incinerator for treating industrial waste. Operational data obtained from the incineration facility were analyzed to determine the short- and long-term effects of PAW spraying on the pressure drop. For the short-term effect, it was confirmed that the pressure drop at the fabric filters always decreased to 0.3-1.2kPa within about 5h after spraying PAW. This effect was expected to be obtained by about one third of present PAW spraying amount. However, from the long-term perspective, the pressure drop showed an increase in the periods of PAW spraying compared with periods for which PAW spraying was not performed. The pressure drop increase was particularly noticeable after the initial PAW spraying, regardless of the age and type of fabric filters used. These results suggest that present PAW spraying causes a temporary pressure drop reduction, leading to short-term energy consumption savings; however, it also causes an increase of the pressure drop over the long-term, degrading the overall operating conditions. Thus, appropriate PAW spraying conditions are needed to make effective use of PAW to reduce the pressure drop at fabric filters from a short- and long-term point of view. Copyright © 2016 Elsevier Ltd. All rights reserved.
The effect of UV-filters on the viability of neuroblastoma (SH-SY5Y) cell line.
Broniowska, Żaneta; Pomierny, Bartosz; Smaga, Irena; Filip, Małgorzata; Budziszewska, Bogusława
2016-05-01
Topical application of cosmetic products, containing ultraviolet filters (UV filters) are recommended as a protection against sunburns and in order to reduce the risk of skin cancer. However, some UV filters can be absorbed through skin and by consuming contaminated food. Among the chemical UV filters, benzophenone-3 (BP-3), 3-(4-methylbenzylidene)camphor (4-MBC) and 2-ethylhexyl-4-methoxycinnamate (OMC) are absorbed through the skin to the greatest extent. So far, these lipophilic compounds were demonstrated to influence the gonadal and thyroid hormone function, but their effect on central nervous system cells has not been investigated, yet. In the present study, we investigated the effect of some UV filters on cell viability and caspase-3 activity in SH-SY5Y cells. It has been found that benzophenone-2 (BP-2), BP-3, 4-methylbenzophenone (4-MBP) and OMC present in the culture medium for 72h in high concentration (10(-5) and 10(-4)M) and 4-MBC only 10(-4)M produced a significant cytotoxic effect, as determined both by the MTT reduction test and LDH release assay. In contrast to necrotic changes, all tested UV filters increased caspase-3 activity in much lower concentrations (from 10(-8) to 10(-7)M). Proapoptotic properties of the test compounds were positively verified by Hoechst staining. The obtained results indicated that UV filters adversely affected the viability of nerve cells, most likely by enhancing the process of apoptosis. The most potent effect was exerted by BP-3 and 4-MBC and at concentrations that may be reached in vivo. Since human exposure to UV filters is significant these compound should be taken into consideration as one of the possible factors involved in pathogenesis of neurodegenerative diseases. Copyright © 2016 Elsevier Inc. All rights reserved.
[Continuum based fast Fourier transform processing of infrared spectrum].
Liu, Qing-Jie; Lin, Qi-Zhong; Wang, Qin-Jun; Li, Hui; Li, Shuai
2009-12-01
To recognize ground objects with infrared spectrum, high frequency noise removing is one of the most important phases in spectrum feature analysis and extraction. A new method for infrared spectrum preprocessing was given combining spectrum continuum processing and Fast Fourier Transform (CFFT). Continuum was firstly removed from the noise polluted infrared spectrum to standardize hyper-spectra. Then the spectrum was transformed into frequency domain (FD) with fast Fourier transform (FFT), separating noise information from target information After noise eliminating from useful information with a low-pass filter, the filtered FD spectrum was transformed into time domain (TD) with fast Fourier inverse transform. Finally the continuum was recovered to the spectrum, and the filtered infrared spectrum was achieved. Experiment was performed for chlorite spectrum in USGS polluted with two kinds of simulated white noise to validate the filtering ability of CFFT by contrast with cubic function of five point (CFFP) in time domain and traditional FFT in frequency domain. A circle of CFFP has limited filtering effect, so it should work much with more circles and consume more time to achieve better filtering result. As for conventional FFT, Gibbs phenomenon has great effect on preprocessing result at edge bands because of special character of rock or mineral spectra, while works well at middle bands. Mean squared error of CFFT is 0. 000 012 336 with cut-off frequency of 150, while that of FFT and CFFP is 0. 000 061 074 with cut-off frequency of 150 and 0.000 022 963 with 150 working circles respectively. Besides the filtering result of CFFT can be improved by adjusting the filter cut-off frequency, and has little effect on working time. The CFFT method overcomes the Gibbs problem of FFT in spectrum filtering, and can be more convenient, dependable, and effective than traditional TD filter methods.
Noll, J.D.; Cecala, A.B.; J.A.Organiscak; Rider, J.P.
2015-01-01
An effective technique to minimize miners’ respirable dust and diesel exposure on mobile mining equipment is to place mine operators in enclosed cabs with designed filtration and pressurization systems. Many factors affect the performance of these enclosed cab systems, and one of the most significant factors is the effectiveness of the filtration system. High-efficiency particulate air (HEPA)-type filters are typically used because they are highly efficient at capturing all types and sizes of particles, including those in the submicron range such as diesel particulate matter (DPM). However, in laboratory tests, minimum efficiency reporting value (MERV) 16 filters have proven to be highly efficient for capturing DPM and respirable dust. Also, MERV 16 filters can be less restrictive to cab airflow and less expensive than HEPA filters. To verify their effectiveness in the field, MERV 16 filters were used in the enclosed cab filtration system on a face drill and roof bolting mining machine and tested at an underground limestone mine. Test results showed that DPM and respirable dust concentrations were reduced by more than 90% when the cabs were properly sealed. However, when the cab door was opened periodically throughout the shift, the reduction efficiency of the MERV 16 filters was reduced to 80% on average. PMID:26236044
Huang, Jing; Huang, Guohe; An, Chunjiang; He, Yuan; Yao, Yao; Zhang, Peng; Shen, Jian
2018-07-01
Global water safety is facing great challenges due to increased population and demand. There is an urgent need to develop suitable water treatment strategy for small rural and remote communities in low-income developing countries. In order to find a low-cost solution, the reduction of E. coli using ceramic water disk coated with nano ZnO was investigated in this study. The performance of modified ceramic disk filters was influenced by several factors in the filter production process. Based on the factorial analysis, the pore size of the disk filters was the most significant factor for influencing E. coli removal efficiency and the clay content was the most significant one for influencing flow rate of modified disk filters. The coating of nano ZnO led to the change of disk filter surface and porosity. The reduction of E. coli could be attributed to both filter retention and photocatalytic antibacterial activity of nano ZnO. The effects of filter operation factors including initial E. coli concentration, illumination time and lamp power on E. coli removal effectiveness were also revealed. The results can help find a safe and cost-effective approach to solve drinking water problems in small rural and remote communities of developing regions. Copyright © 2018 Elsevier Ltd. All rights reserved.
Dee, Scott; Cano, Jean Paul; Spronk, Gordon; Reicks, Darwin; Ruen, Paul; Pitkin, Andrea; Polson, Dale
2012-01-01
Airborne transmission of porcine reproductive and respiratory syndrome virus (PRRSV) is a risk factor for the infection of susceptible populations. Therefore, a long‑term sustainability study of air filtration as a means to reduce this risk was conducted. Participating herds (n = 38) were organized into 4 independent cohorts and the effect of air filtration on the occurrence of new PRRSV infections was analyzed at 3 different levels from September 2008 to January 2012 including the likelihood of infection in contemporary filtered and non-filtered herds, the likelihood of infection before and after implementation of filtration and the time to failure in filtered and non-filtered herds. Results indicated that new PRRSV infections in filtered breeding herds were significantly lower than in contemporary non-filtered control herds (P < 0.01), the odds for a new PRRSV infection in breeding herds before filtration was 7.97 times higher than the odds after filtration was initiated (P < 0.01) and the median time to new PRRSV infections in filtered breeding herds of 30 months was significantly longer than the 11 months observed in non-filtered herds (P < 0.01). In conclusion, across all 3 levels of analysis, the long-term effect of air filtration on reducing the occurrence of new PRRSV infections in the study population was demonstrated. PMID:22754642
Relativistic tests with lunar laser ranging
NASA Astrophysics Data System (ADS)
Hofmann, F.; Müller, J.
2018-02-01
This paper presents the recent version of the lunar laser ranging (LLR) analysis model at the Institut für Erdmessung (IfE), Leibniz Universität Hannover and highlights a few tests of Einstein’s theory of gravitation using LLR data. Investigations related to a possible temporal variation of the gravitational constant, the equivalence principle, the PPN parameters β and γ as well as the geodetic precession were carried out. The LLR analysis model was updated by gravitational effects of the Sun and planets with the Moon as extended body. The higher-order gravitational interaction between Earth and Moon as well as effects of the solid Earth tides on the lunar motion were refined. The basis for the modeled lunar rotation is now a 2-layer core/mantle model according to the DE430 ephemeris. The validity of Einstein’s theory was studied using this updated analysis model and an LLR data set from 1970 to January 2015. Within the estimated accuracies, no deviations from Einstein’s theory are detected. A relative temporal variation of the gravitational constant is estimated as \\dot{G}/G_0=(7.1+/-7.6)×10-14~yr-1 , the test of the equivalence principle gives Δ(m_g/m_i)EM=(-3+/-5)×10-14 and the Nordtvedt parameter \
Development of Navy Methodologies for Relating Logistics Resources to Materiel Readiness.
1984-04-08
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Optimised design for a 1 kJ diode-pumped solid-state laser system
NASA Astrophysics Data System (ADS)
Mason, Paul D.; Ertel, Klaus; Banerjee, Saumyabrata; Phillips, P. Jonathan; Hernandez-Gomez, Cristina; Collier, John L.
2011-06-01
A conceptual design for a kJ-class diode-pumped solid-state laser (DPSSL) system based on cryogenic gas-cooled multislab ceramic Yb:YAG amplifier technology has been developed at the STFC as a building block towards a MJ-class source for inertial fusion energy (IFE) projects such as HiPER. In this paper, we present an overview of an amplifier design optimised for efficient generation of 1 kJ nanosecond pulses at 10 Hz repetition rate. In order to confirm the viability of this technology, a prototype version of this amplifier scaled to deliver 10 J at 10 Hz, DiPOLE, is under development at the Central Laser Facility. A progress update on the status of this system is also presented.
Modeling the sustainability of a ceramic water filter intervention.
Mellor, Jonathan; Abebe, Lydia; Ehdaie, Beeta; Dillingham, Rebecca; Smith, James
2014-02-01
Ceramic water filters (CWFs) are a point-of-use water treatment technology that has shown promise in preventing early childhood diarrhea (ECD) in resource-limited settings. Despite this promise, some researchers have questioned their ability to reduce ECD incidences over the long term since most effectiveness trials conducted to date are less than one year in duration limiting their ability to assess long-term sustainability factors. Most trials also suffer from lack of blinding making them potentially biased. This study uses an agent-based model (ABM) to explore factors related to the long-term sustainability of CWFs in preventing ECD and was based on a three year longitudinal field study. Factors such as filter user compliance, microbial removal effectiveness, filter cleaning and compliance declines were explored. Modeled results indicate that broadly defined human behaviors like compliance and declining microbial effectiveness due to improper maintenance are primary drivers of the outcome metrics of household drinking water quality and ECD rates. The model predicts that a ceramic filter intervention can reduce ECD incidence amongst under two year old children by 41.3%. However, after three years, the average filter is almost entirely ineffective at reducing ECD incidence due to declining filter microbial removal effectiveness resulting from improper maintenance. The model predicts very low ECD rates are possible if compliance rates are 80-90%, filter log reduction efficiency is 3 or greater and there are minimal long-term compliance declines. Cleaning filters at least once every 4 months makes it more likely to achieve very low ECD rates as does the availability of replacement filters for purchase. These results help to understand the heterogeneity seen in previous intervention-control trials and reemphasize the need for researchers to accurately measure confounding variables and ensure that field trials are at least 2-3 years in duration. In summary, the CWF can be a highly effective tool in the fight against ECD, but every effort should be made by implementing agencies to ensure consistent use and maintenance. Copyright © 2013 Elsevier Ltd. All rights reserved.
Accurate mask-based spatially regularized correlation filter for visual tracking
NASA Astrophysics Data System (ADS)
Gu, Xiaodong; Xu, Xinping
2017-01-01
Recently, discriminative correlation filter (DCF)-based trackers have achieved extremely successful results in many competitions and benchmarks. These methods utilize a periodic assumption of the training samples to efficiently learn a classifier. However, this assumption will produce unwanted boundary effects, which severely degrade the tracking performance. Correlation filters with limited boundaries and spatially regularized DCFs were proposed to reduce boundary effects. However, their methods used the fixed mask or predesigned weights function, respectively, which was unsuitable for large appearance variation. We propose an accurate mask-based spatially regularized correlation filter for visual tracking. Our augmented objective can reduce the boundary effect even in large appearance variation. In our algorithm, the masking matrix is converted into the regularized function that acts on the correlation filter in frequency domain, which makes the algorithm fast convergence. Our online tracking algorithm performs favorably against state-of-the-art trackers on OTB-2015 Benchmark in terms of efficiency, accuracy, and robustness.
NASA Technical Reports Server (NTRS)
Schlesinger, R. E.; Johnson, D. R.; Uccellini, L. W.
1983-01-01
In the present investigation, a one-dimensional linearized analysis is used to determine the effect of Asselin's (1972) time filter on both the computational stability and phase error of numerical solutions for the shallow water wave equations, in cases with diffusion but without rotation. An attempt has been made to establish the approximate optimal values of the filtering parameter nu for each of the 'lagged', Dufort-Frankel, and Crank-Nicholson diffusion schemes, suppressing the computational wave mode without materially altering the physical wave mode. It is determined that in the presence of diffusion, the optimum filter length depends on whether waves are undergoing significant propagation. When moderate propagation is present, with or without diffusion, the Asselin filter has little effect on the spatial phase lag of the physical mode for the leapfrog advection scheme of the three diffusion schemes considered.
Self-aligned spatial filtering using laser optical tweezers.
Birkbeck, Aaron L; Zlatanovic, Sanja; Esener, Sadik C
2006-09-01
We present an optical spatial filtering device that has been integrated into a microfluidic system and whose motion and alignment is controlled using a laser optical tweezer. The lithographically patterned micro-optical spatial filter device filters out higher frequency additive noise components by automatically aligning itself in three dimensions to the focus of the laser beam. This self-alignment capability is achieved through the attachment of a refractive optical element directly over the circular aperture or pinhole of the spatial filter. A discussion of two different spatial filter designs is presented along with experimental results that demonstrate the effectiveness of the self-aligned micro-optic spatial filter.
Boundary implications for frequency response of interval FIR and IIR filters
NASA Technical Reports Server (NTRS)
Bose, N. K.; Kim, K. D.
1991-01-01
It is shown that vertex implication results in parameter space apply to interval trigonometric polynomials. Subsequently, it is shown that the frequency responses of both interval FIR and IIR filters are bounded by the frequency responses of certain extreme filters. The results apply directly in the evaluation of properties of designed filters, especially because it is more realistic to bound the filter coefficients from above and below instead of determining those with infinite precision because of finite arithmetic effects. Illustrative examples are provided to show how the extreme filters might be easily derived in any specific interval FIR or IIR filter design problem.
The intractable cigarette ‘filter problem’
2011-01-01
Background When lung cancer fears emerged in the 1950s, cigarette companies initiated a shift in cigarette design from unfiltered to filtered cigarettes. Both the ineffectiveness of cigarette filters and the tobacco industry's misleading marketing of the benefits of filtered cigarettes have been well documented. However, during the 1950s and 1960s, American cigarette companies spent millions of dollars to solve what the industry identified as the ‘filter problem’. These extensive filter research and development efforts suggest a phase of genuine optimism among cigarette designers that cigarette filters could be engineered to mitigate the health hazards of smoking. Objective This paper explores the early history of cigarette filter research and development in order to elucidate why and when seemingly sincere filter engineering efforts devolved into manipulations in cigarette design to sustain cigarette marketing and mitigate consumers' concerns about the health consequences of smoking. Methods Relevant word and phrase searches were conducted in the Legacy Tobacco Documents Library online database, Google Patents, and media and medical databases including ProQuest, JSTOR, Medline and PubMed. Results 13 tobacco industry documents were identified that track prominent developments involved in what the industry referred to as the ‘filter problem’. These reveal a period of intense focus on the ‘filter problem’ that persisted from the mid-1950s to the mid-1960s, featuring collaborations between cigarette producers and large American chemical and textile companies to develop effective filters. In addition, the documents reveal how cigarette filter researchers' growing scientific knowledge of smoke chemistry led to increasing recognition that filters were unlikely to offer significant health protection. One of the primary concerns of cigarette producers was to design cigarette filters that could be economically incorporated into the massive scale of cigarette production. The synthetic plastic cellulose acetate became the fundamental cigarette filter material. By the mid-1960s, the meaning of the phrase ‘filter problem’ changed, such that the effort to develop effective filters became a campaign to market cigarette designs that would sustain the myth of cigarette filter efficacy. Conclusions This study indicates that cigarette designers at Philip Morris, British-American Tobacco, Lorillard and other companies believed for a time that they might be able to reduce some of the most dangerous substances in mainstream smoke through advanced engineering of filter tips. In their attempts to accomplish this, they developed the now ubiquitous cellulose acetate cigarette filter. By the mid-1960s cigarette designers realised that the intractability of the ‘filter problem’ derived from a simple fact: that which is harmful in mainstream smoke and that which provides the smoker with ‘satisfaction’ are essentially one and the same. Only in the wake of this realisation did the agenda of cigarette designers appear to transition away from mitigating the health hazards of smoking and towards the perpetuation of the notion that cigarette filters are effective in reducing these hazards. Filters became a marketing tool, designed to keep and recruit smokers as consumers of these hazardous products. PMID:21504917
A design aid for determining width of filter strips
M.G. Dosskey; M.J. Helmers; D.E. Eisenhauer
2008-01-01
watershed planners need a tool for determining width of filter strips that is accurate enough for developing cost-effective site designs and easy enough to use for making quick determinations on a large number and variety of sites.This study employed the process-based Vegetative Filter Strip Model to evaluate the relationship between filter strip width and trapping...
Apparatus and method for removing mercury vapor from a gas stream
Ganesan, Kumar [Butte, MT
2008-01-01
A metallic filter effectively removes mercury vapor from gas streams. The filter captures the mercury which then can be released and collected as product. The metallic filter is a copper mesh sponge plated with a six micrometer thickness of gold. The filter removes up to 90% of mercury vapor from a mercury contaminated gas stream.
The effect of sampling rate and lowpass filters on saccades - A modeling approach.
Mack, David J; Belfanti, Sandro; Schwarz, Urs
2017-12-01
The study of eye movements has become popular in many fields of science. However, using the preprocessed output of an eye tracker without scrutiny can lead to low-quality or even erroneous data. For example, the sampling rate of the eye tracker influences saccadic peak velocity, while inadequate filters fail to suppress noise or introduce artifacts. Despite previously published guiding values, most filter choices still seem motivated by a trial-and-error approach, and a thorough analysis of filter effects is missing. Therefore, we developed a simple and easy-to-use saccade model that incorporates measured amplitude-velocity main sequences and produces saccades with a similar frequency content to real saccades. We also derived a velocity divergence measure to rate deviations between velocity profiles. In total, we simulated 155 saccades ranging from 0.5° to 60° and subjected them to different sampling rates, noise compositions, and various filter settings. The final goal was to compile a list with the best filter settings for each of these conditions. Replicating previous findings, we observed reduced peak velocities at lower sampling rates. However, this effect was highly non-linear over amplitudes and increasingly stronger for smaller saccades. Interpolating the data to a higher sampling rate significantly reduced this effect. We hope that our model and the velocity divergence measure will be used to provide a quickly accessible ground truth without the need for recording and manually labeling saccades. The comprehensive list of filters allows one to choose the correct filter for analyzing saccade data without resorting to trial-and-error methods.
Nguyen, Dinh Duc; Ngo, Huu Hao; Yoon, Yong Soo; Chang, Soon Woong; Bui, Hong Ha
2016-09-01
The purpose of this paper is to provide a green technology that can clean turbine engine oil filters effectively in ships using ultrasound, with ultrasonic devices having a frequency of 25kHz and different powers of 300W and 600W, respectively. The effects of temperature, ultrasonic cleaning times, pressure losses through the oil filter, solvent washing, and ultrasonic power devices were investigated. In addition, the cleaning efficiency of three modes (hand washing, preliminary washing and ultrasonic washing) were compared to assess their relative effectiveness. Experimental results revealed that the necessary ultrasonic time varied significantly depending on which solvent was used for washing. For instance, the optimum ultrasonic cleaning time was 50-60min when the oil filter was cleaned in a solvent of kerosene oil (KO) and over 80min when in a solvent of diesel oil (DO) using the same ultrasonic generator device (25kHz, 600W) and experimental conditions. Furthermore, microscopic examination did not reveal any damage or breakdown on or within the structure of the filter after ultrasonic cleaning, even in the filter's surfaces at a constantly low frequency of 25kHz and power specific capacity (100W/gal). Overall, it may be concluded that ultrasound-assisted oil filter washing is effective, requiring a significantly shorter time than manual washing. This ultrasonic method also shows promise as a green technology for washing oil filters in turbine engines in general and Vietnamese navy ships in particular, because of its high cleaning efficiency, operational simplicity and savings. Copyright © 2016 Elsevier B.V. All rights reserved.
Tunable Optical Filters Having Electro-optic Whispering-gallery-mode Resonators
NASA Technical Reports Server (NTRS)
Savchenkov, Anatoliy (Inventor); Ilchenko, Vladimir (Inventor); Matsko, Andrey B. (Inventor); Maleki, Lutfollah (Inventor)
2006-01-01
Tunable optical filters using whispering-gallery-mode (WGM) optical resonators are described. The WGM optical resonator in a filter exhibits an electro-optical effect and hence is tunable by applying a control electrical signal.
NASA Astrophysics Data System (ADS)
Khaksar, A.; Fatemi, H.
2012-08-01
To model the filtering behavior of a multi-tooth plasmonic nano-filter (multi-TPNF), an equivalent circuitry composed of a set of serried impedances is considered. The changes caused in its filtering behavior are proposed as a measuring tool to investigate the effect of the geometrical imperfections occurring during the manufacture of the device. Consequently, the effects of changes in the nominal size of each of the geometrical parameters of a multi-TPNF sample, such as its tooth height, d, its tooth width, w, and the separation between two successive teeth, Δ, on its transmittance are investigated. It is observed that each single tooth of the multi-TPNF and also the waveguide between any of its two successive teeth exhibit a very Fabry-Perot interferometer like behavior. The variation of the transmission spectra of a multi-TPNF whose geometrical parameters are imperfect is compared with the desired filter, and also the effect of the number of geometrically imperfect teeth of the multi-TPNF on the filtering spectra is examined.
Transparent air filter for high-efficiency PM2.5 capture.
Liu, Chong; Hsu, Po-Chun; Lee, Hyun-Wook; Ye, Meng; Zheng, Guangyuan; Liu, Nian; Li, Weiyang; Cui, Yi
2015-02-16
Particulate matter (PM) pollution has raised serious concerns for public health. Although outdoor individual protection could be achieved by facial masks, indoor air usually relies on expensive and energy-intensive air-filtering devices. Here, we introduce a transparent air filter for indoor air protection through windows that uses natural passive ventilation to effectively protect the indoor air quality. By controlling the surface chemistry to enable strong PM adhesion and also the microstructure of the air filters to increase the capture possibilities, we achieve transparent, high air flow and highly effective air filters of ~90% transparency with >95.00% removal of PM2.5 under extreme hazardous air-quality conditions (PM2.5 mass concentration >250 μg m(-3)). A field test in Beijing shows that the polyacrylonitrile transparent air filter has the best PM2.5 removal efficiency of 98.69% at high transmittance of ~77% during haze occurrence.
Design of multi-wavelength tunable filter based on Lithium Niobate
NASA Astrophysics Data System (ADS)
Zhang, Ailing; Yao, Yuan; Zhang, Yue; Song, Hongyun
2018-05-01
A multi-wavelength tunable filter is designed. It consists of multiple waveguides among multiple waveguide gratings. A pair of electrodes were placed on both sides of each waveguide. The tunable filter uses the electro-optic effect of Lithium Niobate to tune the phase caused by each waveguide. Consequently, the wavelength and wavelength spacing of the filter are tuned by changing external voltages added on the electrode pairs. The tunable property of the filter is analyzed by phase matching condition and transfer-matrix method. Numerical results show that not only multiple wavelengths with narrow bandwidth are tuned with nearly equal spacing by synchronously changing the voltages added on all electrode pairs, but also the number of wavelengths is determined by the number of phase shifts caused by electrode pairs. Furthermore, due to the electro-optic effect of Lithium Niobate, the tuning speed of the filter can reach the order of ns.
Ding, Tingting; Zheng, Yuanlin; Chen, Xianfeng
2018-04-30
Configurable narrow bandwidth filters are indispensable components in optical communication networks. Here, we present an easily-integrated compact tunable filtering based on polarization-coupling process in a thin periodically poled lithium niobate (PPLN) in a reflective geometry via the transverse electro-optic (EO) effect. The structure, composed of an in-line polarizer and a thinned PPLN chip, forms a phase-shift Solc-type filter with similar mechanism to defected Bragg gratings. The filtering effect can be dynamically switched on and off by a transverse electric filed. Analogy of electromagnetically induced transparency (EIT) transmission spectrum and electrically controllable group delay is experimentally observed. The mechanism features tunable center wavelength in a wide range with respect to temperature and tunable optical delay to the applied voltage, which may offer another way for optical tunable filters or delay lines.
Transparent air filter for high-efficiency PM2.5 capture
NASA Astrophysics Data System (ADS)
Liu, Chong; Hsu, Po-Chun; Lee, Hyun-Wook; Ye, Meng; Zheng, Guangyuan; Liu, Nian; Li, Weiyang; Cui, Yi
2015-02-01
Particulate matter (PM) pollution has raised serious concerns for public health. Although outdoor individual protection could be achieved by facial masks, indoor air usually relies on expensive and energy-intensive air-filtering devices. Here, we introduce a transparent air filter for indoor air protection through windows that uses natural passive ventilation to effectively protect the indoor air quality. By controlling the surface chemistry to enable strong PM adhesion and also the microstructure of the air filters to increase the capture possibilities, we achieve transparent, high air flow and highly effective air filters of ~90% transparency with >95.00% removal of PM2.5 under extreme hazardous air-quality conditions (PM2.5 mass concentration >250 μg m-3). A field test in Beijing shows that the polyacrylonitrile transparent air filter has the best PM2.5 removal efficiency of 98.69% at high transmittance of ~77% during haze occurrence.
NASA Astrophysics Data System (ADS)
Shen, Yuxuan; Wang, Zidong; Shen, Bo; Alsaadi, Fuad E.
2018-07-01
In this paper, the recursive filtering problem is studied for a class of time-varying nonlinear systems with stochastic parameter matrices. The measurement transmission between the sensor and the filter is conducted through a fading channel characterized by the Rice fading model. An event-based transmission mechanism is adopted to decide whether the sensor measurement should be transmitted to the filter. A recursive filter is designed such that, in the simultaneous presence of the stochastic parameter matrices and fading channels, the filtering error covariance is guaranteed to have an upper bound and such an upper bound is then minimized by appropriately choosing filter gain matrix. Finally, a simulation example is presented to demonstrate the effectiveness of the proposed filtering scheme.
Gralewicz, Grzegorz; Owczarek, Grzegorz
2016-09-01
The paper analyses the selected optical parameters of protective optic filters used for protection of the eyes against hazardous radiation within the visible (VIS) and near infrared (NIR) spectrum range. The indexes characterizing transmission and reflection of optic radiation incident on the filter are compared. As it follows from the completed analysis, the newly developed interference filters provide more effective blocking of infrared radiation in comparison with the currently used protective filters.
Ma, Huan; Shen, Henggen; Shui, Tiantian; Li, Qing; Zhou, Liuke
2016-01-01
Size- and time-dependent aerodynamic behaviors of indoor particles, including PM1.0, were evaluated in a school office in order to test the performance of air-cleaning devices using different filters. In-situ real-time measurements were taken using an optical particle counter. The filtration characteristics of filter media, including single-pass efficiency, volume and effectiveness, were evaluated and analyzed. The electret filter (EE) medium shows better initial removal efficiency than the high efficiency (HE) medium in the 0.3–3.5 μm particle size range, while under the same face velocity, the filtration resistance of the HE medium is several times higher than that of the EE medium. During service life testing, the efficiency of the EE medium decreased to 60% with a total purifying air flow of 25 × 104 m3/m2. The resistance curve rose slightly before the efficiency reached the bottom, and then increased almost exponentially. The single-pass efficiency of portable air cleaner (PAC) with the pre-filter (PR) or the active carbon granule filter (CF) was relatively poor. While PAC with the pre-filter and the high efficiency filter (PR&HE) showed maximum single-pass efficiency for PM1.0 (88.6%), PAC with the HE was the most effective at removing PM1.0. The enhancement of PR with HE and electret filters augmented the single-pass efficiency, but lessened the airflow rate and effectiveness. Combined with PR, the decay constant of large-sized particles could be greater than for PACs without PR. Without regard to the lifetime, the electret filters performed better with respect to resource saving and purification improvement. A most penetrating particle size range (MPPS: 0.4–0.65 μm) exists in both HE and electret filters; the MPPS tends to become larger after HE and electret filters are combined with PR. These results serve to provide a better understanding of the indoor particle removal performance of PACs when combined with different kinds of filters in school office buildings. PMID:26742055
Ranking filter methods for concentrating pathogens in lake water
USDA-ARS?s Scientific Manuscript database
Accurately comparing filtration methods for concentrating waterborne pathogens is difficult because of two important water matrix effects on recovery measurements, the effect on PCR quantification and the effect on filter performance. Regarding the first effect, we show how to create a control water...
Charalel, Resmi A; Durack, Jeremy C; Mao, Jialin; Ross, Joseph S; Meltzer, Andrew J; Sedrakyan, Art
2018-03-01
Public awareness of inferior vena cava (IVC) filter-related controversies has been elevated by the Food and Drug Administration (FDA) safety communication in 2010. To examine population level trends in IVC filter utilization, complications, retrieval rates, and subsequent pulmonary embolism (PE) risk. A retrospective cohort study. Patients receiving IVC filters during 2005-2014 in New York State. IVC filter-specific complications, new PE occurrences and IVC filter retrievals were evaluated as time-to-event data using Kaplan-Meier analysis. Estimated cumulative risks were obtained at various timepoints during follow-up. There were 91,873 patients receiving IVC filters between 2005 and 2014 in New York State included in the study. The average patient age was 67 years and 46.6% were male. Age-adjusted rates of IVC filter placement increased from 48 cases/100,000 in 2005 to 52 cases/100,000 in 2009, and decreased afterwards to 36 cases/100,000 in 2014. The estimated risks of having an IVC filter-related complication and filter retrieval within 1 year was 1.5% [95% confidence interval (CI), 1.4%-1.6%] and 3.5% (95% CI, 3.4%-3.6%). One-year retrieval rate was higher post-2010 when compared with pre-2010 years (hazard ratio, 2.70; 95% CI, 2.50-2.91). Among the 58,176 patients who did not have PE events before or at the time of IVC filter placement, the estimated risk of developing subsequent PE at 1 year was 2.0% (95% CI, 1.9%-2.1%). Our findings suggest that FDA communications may be effective in modifying statewide clinical practices. Given the 2% observed PE rate following prophylactic IVC filter placement, large scale pragmatic studies are needed to determine contemporary safety and effectiveness of IVC filters.
Galetti, Valeria; Kujinga, Prosper; Mitchikpè, Comlan Evariste S; Zeder, Christophe; Tay, Fabian; Tossou, Félicien; Hounhouigan, Joseph D; Zimmermann, Michael B; Moretti, Diego
2015-11-01
Zinc deficiency and contaminated water are major contributors to diarrhea in developing countries. Food fortification with zinc has not shown clear benefits, possibly because of low zinc absorption from inhibitory food matrices. We used a novel point-of-use water ultrafiltration device configured with glass zinc plates to produce zinc-fortified, potable water. The objective was to determine zinc bioavailability from filtered water and the efficacy of zinc-fortified water in improving zinc status. In a crossover balanced study, we measured fractional zinc absorption (FAZ) from the zinc-fortified water in 18 healthy Swiss adults using zinc stable isotopes and compared it with zinc-fortified maize porridge. We conducted a 20-wk double-blind randomized controlled trial (RCT) in 277 Beninese school children from rural settings who were randomly assigned to receive a daily portion of zinc-fortified filtered water delivering 2.8 mg Zn (Zn+filter), nonfortified filtered water (Filter), or nonfortified nonfiltered water (Pump) from the local improved supply, acting as the control group. The main outcome was plasma zinc concentration (PZn), and the 3 groups were compared by using mixed-effects models. Secondary outcomes were prevalence of zinc deficiency, diarrhea prevalence, and growth. Geometric mean (-SD, +SD) FAZ was 7-fold higher from fortified water (65.9%; 42.2, 102.4) than from fortified maize (9.1%; 6.0, 13.7; P < 0.001). In the RCT, a significant time-by-treatment effect on PZn (P = 0.026) and on zinc deficiency (P = 0.032) was found; PZn in the Zn+filter group was significantly higher than in the Filter (P = 0.006) and Pump (P = 0.025) groups. We detected no effect on diarrhea or growth, but our study did not have the duration and power to detect such effects. Consumption of filtered water fortified with a low dose of highly bioavailable zinc is an effective intervention in children from rural African settings. Large community-based trials are needed to assess the effectiveness of zinc-fortified filtered water on diarrhea and growth. These trials were registered at clinicaltrials.gov as NCT01636583 and NCT01790321. © 2015 American Society for Nutrition.
Ge, Jia; Feng, Hanlin; Scott, Guy; Fok, Mable P
2015-01-01
A high-speed tunable microwave photonic notch filter with ultrahigh rejection ratio is presented, which is achieved by semiconductor optical amplifier (SOA)-based single-sideband modulation and optical spectral filtering with a phase modulator-incorporated Lyot (PM-Lyot) filter. By varying the birefringence of the phase modulator through electro-optic effect, electrically tuning of the microwave photonic notch filter is experimentally achieved at tens of gigahertz speed. The use of SOA-polarizer based single-sideband modulation scheme provides good sideband suppression over a wide frequency range, resulting in an ultrahigh rejection ratio of the microwave photonic notch filter. Stable filter spectrum with bandstop rejection ratio over 60 dB is observed over a frequency tuning range from 1.8 to 10 GHz. Compare with standard interferometric notch filter, narrower bandwidth and sharper notch profile are achieved with the unique PM-Lyot filter, resulting in better filter selectivity. Moreover, bandwidth tuning is also achieved through polarization adjustment inside the PM-Lyot filter, that the 10-dB filter bandwidth is tuned from 0.81 to 1.85 GHz.
Entropy-guided switching trimmed mean deviation-boosted anisotropic diffusion filter
NASA Astrophysics Data System (ADS)
Nnolim, Uche A.
2016-07-01
An effective anisotropic diffusion (AD) mean filter variant is proposed for filtering of salt-and-pepper impulse noise. The implemented filter is robust to impulse noise ranging from low to high density levels. The algorithm involves a switching scheme in addition to utilizing the unsymmetric trimmed mean/median deviation to filter image noise while greatly preserving image edges, regardless of impulse noise density (ND). It operates with threshold parameters selected manually or adaptively estimated from the image statistics. It is further combined with the partial differential equations (PDE)-based AD for edge preservation at high NDs to enhance the properties of the trimmed mean filter. Based on experimental results, the proposed filter easily and consistently outperforms the median filter and its other variants ranging from simple to complex filter structures, especially the known PDE-based variants. In addition, the switching scheme and threshold calculation enables the filter to avoid smoothing an uncorrupted image, and filtering is activated only when impulse noise is present. Ultimately, the particular properties of the filter make its combination with the AD algorithm a unique and powerful edge-preservation smoothing filter at high-impulse NDs.
The effect of ultraviolet radiation on the anti-inflammatory effect of filters.
Couteau, C; Couteau, O; Chauvet, C; Paparis, E; Coiffard, L J M
2013-08-16
A certain number of filters have notable anti-inflammatory properties with percentage inhibition of PMA-induced edema in mice at over 70%. The question arose as to whether this effect was likely to continue after UV irradiation. It can be noted that 7 filters retain an equivalent anti-inflammatory effect before and after 2h of irradiation in a Suntest device (650 W/m(2)). For 9 filters, the anti-inflammatory effect decreases and for 5 filters, the anti-inflammatory effect increases. Various behaviors should be noted. 3 groups of substances can be distinguished: such as phenylbenzimidazole sulfonic acid which loses its anti-inflammatory character after irradiation (the percentage inhibition falls from 80 to 44%), oxybenzone which retains a constant anti-inflammatory character (89% inhibition before and after irradiation and also octyl methoxycinnamate which becomes very anti-inflammatory (with a percentage inhibition of 93%). The same phenomenon is observed in the case of commercial products. This should be made known as it can have a considerable impact on the results which are displayed on the packaging of sun products. Copyright © 2013 Elsevier B.V. All rights reserved.
Ge, Xiaochen; Shi, Yaocheng; He, Sailing
2014-12-15
The design, fabrication, and characterization of a compact photonic crystal nanobeam drop filter based on the tunneling effect of the degenerate modes are presented. The degeneracy was achieved by tuning the coupling distance between the nanobeam and input/output waveguides. The tunneling effect of degenerate resonances with different symmetries has been verified experimentally. Channel drop filters with an extinction ratio larger than 10 dB and a quality factor of ∼5000 have been experimentally demonstrated.
A deblocking algorithm based on color psychology for display quality enhancement
NASA Astrophysics Data System (ADS)
Yeh, Chia-Hung; Tseng, Wen-Yu; Huang, Kai-Lin
2012-12-01
This article proposes a post-processing deblocking filter to reduce blocking effects. The proposed algorithm detects blocking effects by fusing the results of Sobel edge detector and wavelet-based edge detector. The filtering stage provides four filter modes to eliminate blocking effects at different color regions according to human color vision and color psychology analysis. Experimental results show that the proposed algorithm has better subjective and objective qualities for H.264/AVC reconstructed videos when compared to several existing methods.
Wang, Fei; Zhang, Hui; Liang, Jinsheng; Tang, Qingguo; Li, Yanxia; Shang, Zengyao
2017-01-01
In this work, a new organic-inorganic composite filter was prepared. The thickness, pore size, air permeability, bursting strength and microstructure were characterized systematically, proving that coatings had regulatory effect on filters physical properties. Benefitting from the distinct coatings containing 5% sepiolite nanofibers after five times dilution, the physical properties of corresponding air filter exhibits the most favorable performance and meet the standard of air filter. When used as fuel filter, it satisfies the fuel filter standard and achieves the best performance after six times dilution. The contrast test on engine emission was taken based on auto filters coated with/without as prepared nanofibers. An obvious decrease in the emission of carbon monoxide (CO), hydrocarbons (HC) and nitrogen oxide (NOx) can be observed after installation of composite filter on vehicles. Under the high idle condition, gasoline engine emission decreased by 8.13%, 11.35% and 44.91% for CO, HC and NOx, respectively. When tested in the low idle condition, engine emission reduced by 0.43%, 1.14% and 85.67% for CO, HC and NOx, respectively. The diesel engine emissions of CO, NOx and total amount of HC and NOx decreased by 32.26%, 3.28% and 4.66%, respectively. The results illustrate the composite installation exhibits satisfactory emission reduction effect. PMID:28252034
NASA Astrophysics Data System (ADS)
Wang, Fei; Zhang, Hui; Liang, Jinsheng; Tang, Qingguo; Li, Yanxia; Shang, Zengyao
2017-03-01
In this work, a new organic-inorganic composite filter was prepared. The thickness, pore size, air permeability, bursting strength and microstructure were characterized systematically, proving that coatings had regulatory effect on filters physical properties. Benefitting from the distinct coatings containing 5% sepiolite nanofibers after five times dilution, the physical properties of corresponding air filter exhibits the most favorable performance and meet the standard of air filter. When used as fuel filter, it satisfies the fuel filter standard and achieves the best performance after six times dilution. The contrast test on engine emission was taken based on auto filters coated with/without as prepared nanofibers. An obvious decrease in the emission of carbon monoxide (CO), hydrocarbons (HC) and nitrogen oxide (NOx) can be observed after installation of composite filter on vehicles. Under the high idle condition, gasoline engine emission decreased by 8.13%, 11.35% and 44.91% for CO, HC and NOx, respectively. When tested in the low idle condition, engine emission reduced by 0.43%, 1.14% and 85.67% for CO, HC and NOx, respectively. The diesel engine emissions of CO, NOx and total amount of HC and NOx decreased by 32.26%, 3.28% and 4.66%, respectively. The results illustrate the composite installation exhibits satisfactory emission reduction effect.
Liu, Jui-Nung; Schulmerich, Matthew V.; Bhargava, Rohit; Cunningham, Brian T.
2011-01-01
An alternative to the well-established Fourier transform infrared (FT-IR) spectrometry, termed discrete frequency infrared (DFIR) spectrometry, has recently been proposed. This approach uses narrowband mid-infrared reflectance filters based on guided-mode resonance (GMR) in waveguide gratings, but filters designed and fabricated have not attained the spectral selectivity (≤ 32 cm−1) commonly employed for measurements of condensed matter using FT-IR spectroscopy. With the incorporation of dispersion and optical absorption of materials, we present here optimal design of double-layer surface-relief silicon nitride-based GMR filters in the mid-IR for various narrow bandwidths below 32 cm−1. Both shift of the filter resonance wavelengths arising from the dispersion effect and reduction of peak reflection efficiency and electric field enhancement due to the absorption effect show that the optical characteristics of materials must be taken into consideration rigorously for accurate design of narrowband GMR filters. By incorporating considerations for background reflections, the optimally designed GMR filters can have bandwidth narrower than the designed filter by the antireflection equivalence method based on the same index modulation magnitude, without sacrificing low sideband reflections near resonance. The reported work will enable use of GMR filters-based instrumentation for common measurements of condensed matter, including tissues and polymer samples. PMID:22109445
Ilmiawati, Cimi; Thang, Nguyen Dinh; Iida, Machiko; Maeda, Masao; Ohnuma, Shoko; Yajima, Ichiro; Ohgami, Nobutaka; Oshino, Reina; Al Hossain, M M Aeorangajeb; Ninomiya, Hiromasa; Kato, Masashi
2016-12-01
Since well water utilized for domestic purposes in the Red River Delta of North Vietnam has been reported to be polluted by arsenic, barium, iron, and manganese, household sand filters consisting of various components are used. Information regarding the effectiveness of various sand filters for removal of the four toxic elements in well water is limited. In this study, arsenic levels in 13/20 of well water samples and 1/7 of tap water samples exceeded World Health Organization (WHO) health-based guideline value for drinking water. Moreover, 2/20, 6/20, and 4/20 of well water samples had levels exceeding the present and previous guideline levels for barium, iron, and manganese, respectively. Levels of iron and manganese, but not arsenic, in well water treated by sand filters were lower than those in untreated water, although previous studies showed that sand filters removed all of those elements from water. A low ratio of iron/arsenic in well water may not be sufficient for efficient removal of arsenic from household sand filters. The levels of barium in well water treated by sand filters, especially a filter composed of sand and charcoal, were significantly lower than those in untreated water. Thus, we demonstrated characteristics of sand filters in North Vietnam.
Effect of filter designs on hydraulic properties and well efficiency.
Kim, Byung-Woo
2014-09-01
To analyze the effect of filter pack arrangement on the hydraulic properties and the well efficiency of a well design, a step drawdown was conducted in a sand-filled tank model. Prior to the test, a single filter pack (SFP), granule only, and two dual filter packs (DFPs), type A (granule-pebble) and type B (pebble-granule), were designed to surround the well screen. The hydraulic properties and well efficiencies related to the filter packs were evaluated using the Hazen's, Eden-Hazel's, Jacob's, and Labadie-Helweg's methods. The results showed that the hydraulic properties and well efficiency of the DFPs were higher than those of a SFP, and the clogging effect and wellhead loss related to the aquifer material were the lowest owing to the grain size and the arrangement of the filter pack. The hydraulic conductivity of the DFPs types A and B was about 1.41 and 6.43 times that of a SFP, respectively. In addition, the well efficiency of the DFPs types A and B was about 1.38 and 1.60 times that of the SFP, respectively. In this study, hydraulic property and well efficiency changes were observed according to the variety of the filter pack used. The results differed from the predictions of previous studies on the grain-size ratio. Proper pack-aquifer ratios and filter pack arrangements are primary factors in the construction of efficient water wells, as is the grain ratio, intrinsic permeability (k), and hydraulic conductivity (K) between the grains of the filter packs and the grains of the aquifer. © 2014, National Ground Water Association.
Filter frequency response of time dependent signal using Laplace transform
DOE Office of Scientific and Technical Information (OSTI.GOV)
Shestakov, Aleksei I.
We analyze the effect a filter has on a time dependent signal x(t). If X(s) is the Laplace transform of x and H (s) is the filter Transfer function, the response in frequency space is X (s) H (s). Consequently, in real space, the response is the convolution (x*h) (t), where hi is the Laplace inverse of H. Effects are analyzed and analytically for functions such as (t/t c) 2 e -t/tmore » $$_c$$, where t c = const. We consider lowpass, highpass and bandpass filters.« less
Design of order statistics filters using feedforward neural networks
NASA Astrophysics Data System (ADS)
Maslennikova, Yu. S.; Bochkarev, V. V.
2016-08-01
In recent years significant progress have been made in the development of nonlinear data processing techniques. Such techniques are widely used in digital data filtering and image enhancement. Many of the most effective nonlinear filters based on order statistics. The widely used median filter is the best known order statistic filter. Generalized form of these filters could be presented based on Lloyd's statistics. Filters based on order statistics have excellent robustness properties in the presence of impulsive noise. In this paper, we present special approach for synthesis of order statistics filters using artificial neural networks. Optimal Lloyd's statistics are used for selecting of initial weights for the neural network. Adaptive properties of neural networks provide opportunities to optimize order statistics filters for data with asymmetric distribution function. Different examples demonstrate the properties and performance of presented approach.
Effectiveness of two synthetic fiber filters for removing white cells from AS-1 red cells.
Pikul, F J; Farrar, R P; Boris, M B; Estok, L; Marlo, D; Wildgen, M; Chaplin, H
1989-09-01
Two commercially available synthetic fiber filters were studied for their effectiveness at removing white cells (WBCs) from AS-1-preserved red cells (RBCs) stored less than or equal to 14 days. In all, 65 filtrations were performed. An automated microprocessor-controlled hydraulic system designed for use with cellulose acetate fiber filters was employed to prepare filtered RBCs before release for transfusion. Studies were also carried out on polyester fiber filters, which are designed to be used in-line during transfusion. Residual WBCs were below the accurate counting range of Coulter counters and of conventional manual chamber counts. An isosmotic ammonium chloride RBC lysis method, plus a modified chamber counting technique, permitted a 270-fold increase over the number of WBCs counted by the conventional manual method. For the polyester fiber-filtered products, residual WBCs per unit were not affected by speed of filtration, prior length of storage, or mechanical tapping during filtration. The effectiveness of WBC removal (mean 99.7%), total residual WBCs (means, 4.8 and 5.5 x 10(6], and RBC recovery (mean, 93%) was the same for both filters. The majority of residual WBCs were lymphocytes. WBC removal and RBC recovery were strikingly superior to results reported with nonfiltration methods.
NASA Astrophysics Data System (ADS)
Zheng, Jian-Gang; Yan, Xiongwei; Jiang, Xinying; Wang, Zhenguo; Li, Mingzhong; Zhang, Jun; Zhu, Qihua; Zheng, Wanguo
2017-05-01
Laser Inertial Fusion Energy (IFE) has been attracting the interests of the researchers around the world, because of the promising to the future energy. The Yb:YAG was broadly used in the research field of high-peak power and large energy laser with repetition-rate for IFE because of its outstanding performance, including significant thermal and mechanical capacities, long upper energy level lifetime, high quantum efficiency and highly doping capacity. But it exhibits high saturation fluence at room temperature because of the small emission and absorption cross-section. And at the same time this gain material exhibits self-absorption of laser because of the thermal population at lower laser level at room temperature. Ant it appears to have been solved by means of the cryogenic temperature, but the total efficiency of the laser system will be decreased as the use of cryogenic temperature. The amplified spontaneous emission (ASE) effect of the amplifier can be relaxed by means of edge-cladded absorption material. And the difficulties of edge cladding can be will solved as the emergence of ceramics. But at present the ceramics exhibits high scattering and many disfigurements, which limited the application in the high-power large-energy laser system. So the edge-cladding of Yb:YAG crystal will be a key issue for solution the ASE in amplifier. In this paper, we will introduce a 10J water-cooled DPSSL system, based on Yb:YAG crystal at room temperature. In this system a new edge cladding method has been used, that the Yb:YAG crystal was edge cladded by Cr:YAG ceramics, which was used as the absorption material of ASE. The amplifier was an active mirror water-cooled room temperature amplifier. With the help of this edge cladding the ASE has been lowered, and about 5 times small signal gain has been obtained in a single pass amplification, which was much higher than the earlier of 2 times. And the wavefront aberrance of the laser beam was also reduced due to the thermal equilibrium between the edge cladding and the gain region. the amplifiers can be stably operated under 10Hz. Finally the output of the laser system was about 7.15J@10Hz and 10.8J@1-2Hz. The total optical-to-optical efficiency was about 8.3% for 1-2Hz (under the condition of 120kW/1ms pumping, 880mJ input and 10.8J output) and 5.6% for 10Hz.
Multispectral Image Enhancement Through Adaptive Wavelet Fusion
2016-09-14
13. SUPPLEMENTARY NOTES 14. ABSTRACT This research developed a multiresolution image fusion scheme based on guided filtering . Guided filtering can...effectively reduce noise while preserving detail boundaries. When applied in an iterative mode, guided filtering selectively eliminates small scale...details while restoring larger scale edges. The proposed multi-scale image fusion scheme achieves spatial consistency by using guided filtering both at
Faraday anomalous dispersion optical filters
NASA Technical Reports Server (NTRS)
Shay, T. M.; Yin, B.; Alvarez, L. S.
1993-01-01
The effect of Faraday anomalous dispersion optical filters on infrared and blue transitions of some alkali atoms is calculated. A composite system is designed to further increase the background noise rejection. The measured results of the solar background rejection and image quality through the filter are presented. The results show that the filter may provide high transmission and high background noise rejection with excellent image quality.
NASA Astrophysics Data System (ADS)
Nazifah, A.; Norhanna, S.; Shah, S. I.; Zakaria, A.
2014-11-01
This study aimed to investigate the effects of material filter technique on Tc-99m spectra and performance parameters of Philip ADAC forte dual head gamma camera. Thickness of material filter was selected on the basis of percentage attenuation of various gamma ray energies by different thicknesses of zinc material. A cylindrical source tank of NEMA single photon emission computed tomography (SPECT) Triple Line Source Phantom filled with water and Tc-99m radionuclide injected was used for spectra, uniformity and sensitivity measurements. Vinyl plastic tube was used as a line source for spatial resolution. Images for uniformity were reconstructed by filtered back projection method. Butterworth filter of order 5 and cut off frequency 0.35 cycles/cm was selected. Chang's attenuation correction method was applied by selecting 0.13/cm linear attenuation coefficient. Count rate was decreased with material filter from the compton region of Tc-99m energy spectrum, also from the photopeak region. Spatial resolution was improved. However, uniformity of tomographic image was equivocal, and system volume sensitivity was reduced by material filter. Material filter improved system's spatial resolution. Therefore, the technique may be used for phantom studies to improve the image quality.
Napotnik, Julie A; Baker, Derek; Jellison, Kristen L
2017-03-21
The main objective of this study was to build several full-scale biosand filters (BSFs) and assess the long-term (9 month) efficacy for particulate and Escherichia coli removal under simulated real-world usage. Four replicates of three different filter designs were built: the traditional concrete BSF and two scaled-down versions that use a 5 or 2 gal bucket as the casing material. The smaller sand bed depths in the bucket-sized filters did not impact filter performance with respect to (i) turbidity and E. coli removal or (ii) effluent levels of turbidity and E. coli. All filters produced effluents with a mean turbidity of <0.6 nephelometric turbidity unit. In addition, 78, 74, and 72% of effluent samples for the concrete, 5 gal, and 2 gal filters, respectively, had E. coli concentrations of <1 colony-forming unit/100 mL. The bucket-sized filters were found to be a potential alternative to the concrete BSFs for the removal of E. coli and turbidity from drinking water. Because smaller BSFs must be filled more frequently than larger BSFs to produce comparable water volumes, the effect of shorter pause periods on BSF performance should be investigated.
Herrmann, Inga; Jourak, Amir; Hedström, Annelie; Lundström, T. Staffan; Viklander, Maria
2013-01-01
Sorption by active filter media can be a convenient option for phosphorus (P) removal and recovery from wastewater for on-site treatment systems. There is a need for a robust laboratory method for the investigation of filter materials to enable a reliable estimation of their longevity. The objectives of this study were to (1) investigate and (2) quantify the effect of hydraulic loading rate and influent source (secondary wastewater and synthetic phosphate solution) on P binding capacity determined in laboratory column tests and (3) to study how much time is needed for the P to react with the filter material (reaction time). To study the effects of these factors, a 22 factorial experiment with 11 filter columns was performed. The reaction time was studied in a batch experiment. Both factors significantly (α = 0.05) affected the P binding capacity negatively, but the interaction of the two factors was not significant. Increasing the loading rate from 100 to 1200 L m−2 d−1 decreased P binding capacity from 1.152 to 0.070 g kg−1 for wastewater filters and from 1.382 to 0.300 g kg−1 for phosphate solution filters. At a loading rate of 100 L m−2 d−1, the average P binding capacity of wastewater filters was 1.152 g kg−1 as opposed to 1.382 g kg−1 for phosphate solution filters. Therefore, influent source or hydraulic loading rate should be carefully controlled in the laboratory. When phosphate solution and wastewater were used, the reaction times for the filters to remove P were determined to be 5 and 15 minutes, respectively, suggesting that a short residence time is required. However, breakthrough in this study occurred unexpectedly quickly, implying that more time is needed for the P that has reacted to be physically retained in the filter. PMID:23936313
Li, Sui-Xian
2018-05-07
Previous research has shown that the effectiveness of selecting filter sets from among a large set of commercial broadband filters by a vector analysis method based on maximum linear independence (MLI). However, the traditional MLI approach is suboptimal due to the need to predefine the first filter of the selected filter set to be the maximum ℓ₂ norm among all available filters. An exhaustive imaging simulation with every single filter serving as the first filter is conducted to investigate the features of the most competent filter set. From the simulation, the characteristics of the most competent filter set are discovered. Besides minimization of the condition number, the geometric features of the best-performed filter set comprise a distinct transmittance peak along the wavelength axis of the first filter, a generally uniform distribution for the peaks of the filters and substantial overlaps of the transmittance curves of the adjacent filters. Therefore, the best-performed filter sets can be recognized intuitively by simple vector analysis and just a few experimental verifications. A practical two-step framework for selecting optimal filter set is recommended, which guarantees a significant enhancement of the performance of the systems. This work should be useful for optimizing the spectral sensitivity of broadband multispectral imaging sensors.
Effect of high latitude filtering on NWP skill
NASA Technical Reports Server (NTRS)
Kalnay, E.; Takacs, L. L.; Hoffman, R. N.
1984-01-01
The high latitude filtering techniques commonly employed in global grid point models to eliminate the high frequency waves associated with the convergence of meridians, can introduce serious distortions which ultimately affect the solution at all latitudes. Experiments completed so far with the 4 deg x 5 deg, 9-level GLAS Fourth Order Model indicate that the high latitude filter currently in operation affects only minimally its forecasting skill. In one case, however, the use of pressure gradient filter significantly improved the forecast. Three day forecasts with the pressure gradient and operational filters are compared as are 5-day forecasts with no filter.
Examination of cryogenic filters for multistage RF filtering in ultralow temperature experiments
NASA Astrophysics Data System (ADS)
Zavyalov, V. V.; Chernyaev, S. A.; Shein, K. V.; Shukaleva, A. G.; Arutyunov, K. Yu
2018-03-01
Cryo-filters are essential while studying electronic properties of nanoscale structures at very low temperatures. In this report we present the simple measuring methodology and experimental impedance characteristics of customized lumped filters cooled down to 4.2K in the 10 Hz-500 MHz frequency range. In particular, we tested the home-made permalloy-core RL filters, the MurataTMChip Ferrite Bead filter, and the ToshibaTMAmobeadsTMcores. We use the high-frequency generalization of four-terminal sensing method to account for the wiring retardation effects, which are important when working with ultralow temperature systems.
Photon counting x-ray imaging with K-edge filtered x-rays: A simulation study.
Atak, Haluk; Shikhaliev, Polad M
2016-03-01
In photon counting (PC) x-ray imaging and computed tomography (CT), the broad x-ray spectrum can be split into two parts using an x-ray filter with appropriate K-edge energy, which can improve material decomposition. Recent experimental study has demonstrated substantial improvement in material decomposition with PC CT when K-edge filtered x-rays were used. The purpose of the current work was to conduct further investigations of the K-edge filtration method using comprehensive simulation studies. The study was performed in the following aspects: (1) optimization of the K-edge filter for a particular imaging configuration, (2) effects of the K-edge filter parameters on material decomposition, (3) trade-off between the energy bin separation, tube load, and beam quality with K-edge filter, (4) image quality of general (unsubtracted) images when a K-edge filter is used to improve dual energy (DE) subtracted images, and (5) improvements with K-edge filtered x-rays when PC detector has limited energy resolution. The PC x-ray images of soft tissue phantoms with 15 and 30 cm thicknesses including iodine, CaCO3, and soft tissue contrast materials, were simulated. The signal to noise ratio (SNR) of the contrast elements was determined in general and material-decomposed images using K-edge filters with different atomic numbers and thicknesses. The effect of the filter atomic number and filter thickness on energy separation factor and SNR was determined. The boundary conditions for the tube load and halfvalue layer were determined when the K-edge filters are used. The material-decomposed images were also simulated using PC detector with limited energy resolution, and improvements with K-edge filtered x-rays were quantified. The K-edge filters with atomic numbers from 56 to 71 and K-edge energies 37.4-63.4 keV, respectively, can be used for tube voltages from 60 to 150 kVp, respectively. For a particular tube voltage of 120 kVp, the Gd and Ho were the optimal filter materials to achieve highest SNR. For a particular K-edge filter of Gd and tube voltage of 120 kVp, the filter thickness 0.6 mm provided maximum SNR for considered imaging applications. While K-edge filtration improved SNR of CaCO3 and iodine by 41% and 36%, respectively, in DE subtracted images, it did not deteriorate SNR in general images. For x-ray imaging with nonideal PC detector, the positive effect of the K-edge filter was increased when FWHM energy resolution was degraded, and maximum improvement was at 60% FWHM. This study has shown that K-edge filtered x-rays can provide substantial improvements of material selective PC x-ray and CT imaging for nearly all imaging applications using 60-150 kVp tube voltages. Potential limitations such as tube load, beam hardening, and availability of filter material were shown to not be critical.
NASA Technical Reports Server (NTRS)
Montgomery, R. C.; Tabak, D.
1979-01-01
The study involves the bank of filters approach to analytical redundancy management since this is amenable to microelectronic implementation. Attention is given to a study of the UD factorized filter to determine if it gives more accurate estimates than the standard Kalman filter when data processing word size is reduced. It is reported that, as the word size is reduced, the effect of modeling error dominates the filter performance of the two filters. However, the UD filter is shown to maintain a slight advantage in tracking performance. It is concluded that because of the UD filter's stability in the serial processing mode, it remains the leading candidate for microelectronic implementation.
System identification of jet engines
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sugiyama, N.
2000-01-01
System identification plays an important role in advanced control systems for jet engines, in which controls are performed adaptively using data from the actual engine and the identified engine. An identification technique for jet engine using the Constant Gain Extended Kalman Filter (CGEKF) is described. The filter is constructed for a two-spool turbofan engine. The CGEKF filter developed here can recognize parameter change in engine components and estimate unmeasurable variables over whole flight conditions. These capabilities are useful for an advanced Full Authority Digital Electric Control (FADEC). Effects of measurement noise and bias, effects of operating point and unpredicted performancemore » change are discussed. Some experimental results using the actual engine are shown to evaluate the effectiveness of CGEKF filter.« less
Solar Rejection Filter for Large Telescopes
NASA Technical Reports Server (NTRS)
Hemmati, Hamid; Lesh, James
2009-01-01
To reject solar radiation photons at the front aperture for large telescopes, a mosaic of large transmission mode filters is placed in front of the telescope or at the aperture of the dome. Filtering options for effective rejection of sunlight include a smaller filter down-path near the focus of the telescope, and a large-diameter filter located in the front of the main aperture. Two types of large filters are viable: reflectance mode and transmittance mode. In the case of reflectance mode, a dielectric coating on a suitable substrate (e.g. a low-thermal-expansion glass) is arranged to reflect only a single, narrow wavelength and to efficiently transmit all other wavelengths. These coatings are commonly referred to as notch filter. In this case, the large mirror located in front of the telescope aperture reflects the received (signal and background) light into the telescope. In the case of transmittance mode, a dielectric coating on a suitable substrate (glass, sapphire, clear plastic, membrane, and the like) is arranged to transmit only a single wavelength and to reject all other wavelengths (visible and near IR) of light. The substrate of the large filter will determine its mass. At first glance, a large optical filter with a diameter of up to 10 m, located in front of the main aperture, would require a significant thickness to avoid sagging. However, a segmented filter supported by a structurally rugged grid can support smaller filters. The obscuration introduced by the grid is minimal because the total area can be made insignificant. This configuration can be detrimental to a diffraction- limited telescope due to diffraction effects at the edges of each sub-panel. However, no discernable degradation would result for a 20 diffraction-limit telescope (a photon bucket). Even the small amount of sagging in each subpanel should have minimal effect in the performance of a non-diffraction limited telescope because the part has no appreciable optical power. If the front aperture filter is integrated with the telescope dome, it will reject heat from the dome and will significantly reduce dome temperature regulation requirements and costs. Also, the filter will protect the telescope optics from dust and other contaminants in the atmosphere. It will be simpler to clean or replace this filter than the telescope primary mirror. It may be necessary to paint the support grid with a highly reflective material to avoid overheating.
Toxicity of organic UV-filters to the aquatic midge Chironomus riparius.
Campos, Diana; Gravato, Carlos; Quintaneiro, Carla; Golovko, Oksana; Žlábek, Vladimír; Soares, Amadeu M V M; Pestana, João L T
2017-09-01
Despite the frequent detection of organic ultraviolet-filters (UV-filters) in freshwater sediments, there is a lack of ecotoxicological data undermining a correct risk assessment for these emerging contaminants. The present study assessed the effects of three of the most commonly used UV-filters (benzophenone-3 - BP3; 3-(4-methylbenzylidene)camphor - 4-MBC and octocrylene - OC) on Chironomus riparius life history and biochemical responses. Standard ecotoxicological assays confirmed that all compounds impaired growth of C. riparius larvae and induced developmental effects such as delayed emergence and a reduction of imagoes weight. Concerning the biochemical responses analysed no evidences of oxidative damage in lipids or neurotoxicity (tested assessing acetylcholinesterase activity) were observed for any of the tested compounds. However, 4-MBC exposure induced a decrease in catalase activity and an increase in glutathione-S-transferase activity at 14.13mg/Kg while OC exposure caused an increase in total glutathione levels at 0.23 and 18.23mg/Kg. Exposure to all UV-filters tested, increased energy consumption on C. riparius with significant differences above 1.00mg/Kg for BP3, 0.09mg/Kg for 4-MBC and 2.13mg/Kg for OC. These results suggest that environmental relevant concentrations of UV-filters can cause deleterious effects to aquatic benthic species, such as C. riparius, and call for further research concerning effects of organic UV-filters on natural invertebrate communities and ecosystem functioning. Copyright © 2017 Elsevier Inc. All rights reserved.
Modulation of Radio Frequency Signals by Nonlinearly Generated Acoustic Fields
2014-01-01
roll -off in attenuation, known as the filter skirt. Therefore, the use of filters can be inadequate if the small signals are close in frequency to the...effect can be avoided by introducing filters into the nonlinear measurement system that have much smaller bandwidths, capable of isolating narrow...contribution from each source of modulation has not been done as isolating each effect during measurement is currently infeasible. To better
BMP FILTERS: UPFLOW VS. DOWNFLOW
Filtration methods have been found to be effective in reducing pollutant levels in stormwater. The main drawback of these methods is that the filters get clogged frequently and require periodical maintenance. In stormwater treatment, because of the cost of pumping, the filters ar...
Bowtie filters for dedicated breast CT: Analysis of bowtie filter material selection.
Kontson, Kimberly; Jennings, Robert J
2015-09-01
For a given bowtie filter design, both the selection of material and the physical design control the energy fluence, and consequently the dose distribution, in the object. Using three previously described bowtie filter designs, the goal of this work is to demonstrate the effect that different materials have on the bowtie filter performance measures. Three bowtie filter designs that compensate for one or more aspects of the beam-modifying effects due to the differences in path length in a projection have been designed. The nature of the designs allows for their realization using a variety of materials. The designs were based on a phantom, 14 cm in diameter, composed of 40% fibroglandular and 60% adipose tissue. Bowtie design #1 is based on single material spectral matching and produces nearly uniform spectral shape for radiation incident upon the detector. Bowtie design #2 uses the idea of basis-material decomposition to produce the same spectral shape and intensity at the detector, using two different materials. With bowtie design #3, it is possible to eliminate the beam hardening effect in the reconstructed image by adjusting the bowtie filter thickness so that the effective attenuation coefficient for every ray is the same. Seven different materials were chosen to represent a range of chemical compositions and densities. After calculation of construction parameters for each bowtie filter design, a bowtie filter was created using each of these materials (assuming reasonable construction parameters were obtained), resulting in a total of 26 bowtie filters modeled analytically and in the penelope Monte Carlo simulation environment. Using the analytical model of each bowtie filter, design profiles were obtained and energy fluence as a function of fan-angle was calculated. Projection images with and without each bowtie filter design were also generated using penelope and reconstructed using FBP. Parameters such as dose distribution, noise uniformity, and scatter were investigated. Analytical calculations with and without each bowtie filter show that some materials for a given design produce bowtie filters that are too large for implementation in breast CT scanners or too small to accurately manufacture. Results also demonstrate the ability to manipulate the energy fluence distribution (dynamic range) by using different materials, or different combinations of materials, for a given bowtie filter design. This feature is especially advantageous when using photon counting detector technology. Monte Carlo simulation results from penelope show that all studied material choices for bowtie design #2 achieve nearly uniform dose distribution, noise uniformity index less than 5%, and nearly uniform scatter-to-primary ratio. These same features can also be obtained using certain materials with bowtie designs #1 and #3. With the three bowtie filter designs used in this work, the selection of material is an important design consideration. An appropriate material choice can improve image quality, dose uniformity, and dynamic range.
Bowtie filters for dedicated breast CT: Analysis of bowtie filter material selection
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kontson, Kimberly, E-mail: Kimberly.Kontson@fda.hhs.gov; Jennings, Robert J.
Purpose: For a given bowtie filter design, both the selection of material and the physical design control the energy fluence, and consequently the dose distribution, in the object. Using three previously described bowtie filter designs, the goal of this work is to demonstrate the effect that different materials have on the bowtie filter performance measures. Methods: Three bowtie filter designs that compensate for one or more aspects of the beam-modifying effects due to the differences in path length in a projection have been designed. The nature of the designs allows for their realization using a variety of materials. The designsmore » were based on a phantom, 14 cm in diameter, composed of 40% fibroglandular and 60% adipose tissue. Bowtie design #1 is based on single material spectral matching and produces nearly uniform spectral shape for radiation incident upon the detector. Bowtie design #2 uses the idea of basis-material decomposition to produce the same spectral shape and intensity at the detector, using two different materials. With bowtie design #3, it is possible to eliminate the beam hardening effect in the reconstructed image by adjusting the bowtie filter thickness so that the effective attenuation coefficient for every ray is the same. Seven different materials were chosen to represent a range of chemical compositions and densities. After calculation of construction parameters for each bowtie filter design, a bowtie filter was created using each of these materials (assuming reasonable construction parameters were obtained), resulting in a total of 26 bowtie filters modeled analytically and in the PENELOPE Monte Carlo simulation environment. Using the analytical model of each bowtie filter, design profiles were obtained and energy fluence as a function of fan-angle was calculated. Projection images with and without each bowtie filter design were also generated using PENELOPE and reconstructed using FBP. Parameters such as dose distribution, noise uniformity, and scatter were investigated. Results: Analytical calculations with and without each bowtie filter show that some materials for a given design produce bowtie filters that are too large for implementation in breast CT scanners or too small to accurately manufacture. Results also demonstrate the ability to manipulate the energy fluence distribution (dynamic range) by using different materials, or different combinations of materials, for a given bowtie filter design. This feature is especially advantageous when using photon counting detector technology. Monte Carlo simulation results from PENELOPE show that all studied material choices for bowtie design #2 achieve nearly uniform dose distribution, noise uniformity index less than 5%, and nearly uniform scatter-to-primary ratio. These same features can also be obtained using certain materials with bowtie designs #1 and #3. Conclusions: With the three bowtie filter designs used in this work, the selection of material is an important design consideration. An appropriate material choice can improve image quality, dose uniformity, and dynamic range.« less
[Micropore filters for measuring red blood cell deformability and their pore diameters].
Niu, X; Yan, Z
2001-09-01
Micropore filters are the most important components in micropore filtration testes for assessing red blood cell (RBC) deformability. With regard to their appearance and filtration behaviors, comparisons are made for different kinds of filters currently in use. Nickel filters with regular geometric characteristics are found to be more sensitive to the effects of physical, chemical, especially pathological factors on the RBC deformability. We have critically reviewed the following viewpoint that filters with 3 microns pore diameter are more sensitive to cell volume than to internal viscosity while filters with 5 microns pore diameter are just the opposite. After analyzing the experiment results with 3 microns and 5 microns filters, we point out that filters with smaller pore diameters are more suitable for assessing the RBC deformability.
Glass Frit Filters for Collecting Metal Oxide Nanoparticles
NASA Technical Reports Server (NTRS)
Ackerman, John; Buttry, Dan; Irvine, Geoffrey; Pope, John
2005-01-01
Filter disks made of glass frit have been found to be effective as means of high-throughput collection of metal oxide particles, ranging in size from a few to a few hundred nanometers, produced in gas-phase condensation reactors. In a typical application, a filter is placed downstream of the reactor and a valve is used to regulate the flow of reactor exhaust through the filter. The exhaust stream includes a carrier gas, particles, byproducts, and unreacted particle-precursor gas. The filter selectively traps the particles while allowing the carrier gas, the byproducts, and, in some cases, the unreacted precursor, to flow through unaffected. Although the pores in the filters are much larger than the particles, the particles are nevertheless trapped to a high degree: Anecdotal information from an experiment indicates that 6-nm-diameter particles of MnO2 were trapped with greater than 99-percent effectiveness by a filtering device comprising a glass-frit disk having pores 70 to 100 micrometer wide immobilized in an 8-cm-diameter glass tube equipped with a simple twist valve at its downstream end.
Color filter array pattern identification using variance of color difference image
NASA Astrophysics Data System (ADS)
Shin, Hyun Jun; Jeon, Jong Ju; Eom, Il Kyu
2017-07-01
A color filter array is placed on the image sensor of a digital camera to acquire color images. Each pixel uses only one color, since the image sensor can measure only one color per pixel. Therefore, empty pixels are filled using an interpolation process called demosaicing. The original and the interpolated pixels have different statistical characteristics. If the image is modified by manipulation or forgery, the color filter array pattern is altered. This pattern change can be a clue for image forgery detection. However, most forgery detection algorithms have the disadvantage of assuming the color filter array pattern. We present an identification method of the color filter array pattern. Initially, the local mean is eliminated to remove the background effect. Subsequently, the color difference block is constructed to emphasize the difference between the original pixel and the interpolated pixel. The variance measure of the color difference image is proposed as a means of estimating the color filter array configuration. The experimental results show that the proposed method is effective in identifying the color filter array pattern. Compared with conventional methods, our method provides superior performance.
Johnson, Christopher M; Pate, Mariah B; Postma, Gregory N
2018-04-01
Standard KTP laser (potassium titanyl phosphate) wavelength-specific protective eyewear often impairs visualization of tissue changes during laser treatment. This sometimes necessitates eyewear removal to evaluate tissue effects, which wastes time and poses safety concerns. The objective was to determine if "virtual" or "electronic" chromoendoscopy filters, as found on some endoscopy platforms, could alleviate the restricted visualization inherent to protective eyewear. A KTP laser was applied to porcine laryngeal tissue and recorded via video laryngoscopy with 1 optical (Olympus Narrow Band Imaging) and 8 digital (Pentax Medical I-scan) chromoendoscopy filters. Videos were viewed by 11 otolaryngologists wearing protective eyewear. Using a discrete visual analog scale, they rated each filter on its ability to improve visualization,. No filter impaired visualization; 5 of 9 improved visualization. Based on statistical significance, the number of positive responses, and the lack of negative responses, narrow band imaging and the I-scan tone enhancement filter for leukoplakia performed best. These filters could shorten procedure time and improve safety; therefore, further clinical evaluation is warranted.
NASA Technical Reports Server (NTRS)
Subramanyam, Guru; Vignesparamoorthy, Sivaruban; Mueller, Carl; VanKeuls, Fred; Warner, Joseph; Miranda, Felix A.
2001-01-01
The main purpose of this work is to study the effect of a selectively etched ferroelectric thin film layer on the performance of an electrically tunable filter. An X-band tunable filter was designed, fabricated and tested on a selectively etched Barium Strontium Titanate (BSTO) ferroelectric thin film layer. Tunable filters with varying lengths of BSTO thin-film in the input and output coupling gaps were modeled, as well as experimentally tested. Experimental results showed that filters with coupling gaps partially filled with BSTO maintained frequency tunability and improved the insertion loss by approx. 2dB. To the best of our knowledge, these results represent the first experimental demonstration of the advantages of selective etching in the performance of thin film ferroelectric-based tunable microwave components.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Noble, J.H.; Davie, R.L.
1961-05-01
Filter tests were conducted to determine the most suitable filter for removing large quantities of aluminum corrosion product (boehmite) from reactor water. Filters tested included the following: wire-wound, sintered filter elements, sintered ceramic fllter elements, cotton stringwound filter elements, felted-cotton filter elements, cation resin, adsorption resin, diatomaceous earth precoat filter, and a wood-cellulose precoat filter. Parameters measured were flow rate, filter-influent and -effluent boehmite concentration, pressure drop, and final filter load. The pressure drop and efficiency of the filters was correlated with boehmite load. Boehmite deposits on filters as a nonporous gelatinous cake, and causes a rapidly increasing pressure drop.more » Tests indicate that the optimum load with filter elements and precoat filters is achieved at a pressure drop of 25 psi. Very little additional load can be obtained by operating to a higher pressure drop. Of the filters tested, the precoat filter snd 40 to 60 mesh cation resin were the more effective in removing boehmite. The efficiency of the precoat filter was in excess of 99%, and the efficiency of the cation resin was for the most part in excess of 95%. For various reasons, the other filters were eliminated from final consideration. The test program and available literature indicated that an element type precoat filter using wood cellulose as the precoat media would be most suitable for the proposed application. (auth)« less
Ruppelt, Jan P; Tondera, Katharina; Schreiber, Christiane; Kistemann, Thomas; Pinnekamp, Johannes
2018-05-01
Combined sewer overflows (CSOs) introduce numerous pathogens from fecal contamination, such as bacteria and viruses, into surface waters, thus endangering human health. In Germany, retention soil filters (RSFs) treat CSOs at sensitive discharge points and can contribute to reducing these hygienically relevant microorganisms. In this study, we evaluated the extent of how dry period, series connection and filter layer thickness influence the reduction efficiency of RSFs for Escherichia coli (E. coli), intestinal enterococci (I. E.) and somatic coliphages. To accomplish this, we had four pilot scale RSFs built on a test field at the wastewater treatment plant Aachen-Soers. While two filters were replicates, the other two filters were installed in a series connection. Moreover, one filter had a thinner filtration layer than the other three. Between April 2015 and December 2016, the RSFs were loaded in 37 trials with pre-conditioned CSO after dry periods ranging from 4 to 40 days. During 17 trials, samples for microbial analysis were taken and analyzed. The series connection of two filters showed that the removal increases when two systems with a filter layer of the same height are operated in series. Since the microorganisms are exposed twice to the environmental conditions on the filter surface and in the upper filter layers, there is a greater chance for abiotic adsorption increase. The same effect could be shown when filters with different depths were compared: the removal efficiency increases as filter thickness increases. This study provides new evidence that regardless of seasonal effects and dry period, RSFs can improve hygienic situation significantly. Copyright © 2018 Elsevier GmbH. All rights reserved.
The effect of bandwidth on filter instrument total ozone accuracy
NASA Technical Reports Server (NTRS)
Basher, R. E.
1977-01-01
The effect of the width and shape of the New Zealand filter instrument's passbands on measured total-ozone accuracy is determined using a numerical model of the spectral measurement process. The model enables the calculation of corrections for the 'bandwidth-effect' error and shows that highly attenuating passband skirts and well-suppressed leakage bands are at least as important as narrow half-bandwidths. Over typical ranges of airmass and total ozone, the range in the bandwidth-effect correction is about 2% in total ozone for the filter instrument, compared with about 1% for the Dobson instrument.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bozlar, Ugur; Edmunds, J. Stewart; Turba, Ulku C.
The objective of this study was to explore the role of three-dimensional (3-D) rotational angiography (RA) of the inferior vena cava (IVC; 3-D CV) before filter retrieval and its impact on treatment planning compared with standard anteroposterior cavography (sCV). Thirty patients underwent sCV and 3-D CV before IVC filter retrieval. Parameters assessed were: projection of filter arms or legs beyond the caval lumen, thrombus burden within the filter and IVC, and orientation of the filter within IVC. Skin and effective radiation doses were calculated. Statistical analysis was performed using paired Student t test and nonparametric McNemar's test. Standard anteroposterior cavographymore » detected 49 filter arms or legs projecting beyond the caval lumen in 25 patients. Three-dimensional CV demonstrated 89 filter arms or legs projecting beyond the caval lumen in 28 patients. Twenty-two patients had additional filter arms or legs projecting beyond the caval lumen detected on 3-D CV that were not detected on sCV (p < 0.001). Filter apex tilt detection differed significantly (p < 0.001) between sCV and 3-D CV, with 3-D CV being more accurate. The filter apex abutted the IVC wall in 10 patients (33%) on 3-D CV, but this was diagnosed in only 3 patients (10%) with sCV. Thrombus was detected in 8 patients (27%), 1 thrombus of which was seen only on 3-D CV, and treatment was changed in this patient because of thrombus size. Mean effective radiation doses for 3-D CV were approximately two times higher than for sCV (1.68 vs. 0.86 mSv), whereas skin doses were three times lower (12.87 vs. 35.86 mGy). Compared with sCV, performing 3-D CV before optional IVC filter retrieval has the potential to improve assessment of filter arms or legs projecting beyond the caval lumen, filter orientation, and thrombus burden.« less
NASA Astrophysics Data System (ADS)
Li, Zhong-xiao; Li, Zhen-chun
2016-09-01
The multichannel predictive deconvolution can be conducted in overlapping temporal and spatial data windows to solve the 2D predictive filter for multiple removal. Generally, the 2D predictive filter can better remove multiples at the cost of more computation time compared with the 1D predictive filter. In this paper we first use the cross-correlation strategy to determine the limited supporting region of filters where the coefficients play a major role for multiple removal in the filter coefficient space. To solve the 2D predictive filter the traditional multichannel predictive deconvolution uses the least squares (LS) algorithm, which requires primaries and multiples are orthogonal. To relax the orthogonality assumption the iterative reweighted least squares (IRLS) algorithm and the fast iterative shrinkage thresholding (FIST) algorithm have been used to solve the 2D predictive filter in the multichannel predictive deconvolution with the non-Gaussian maximization (L1 norm minimization) constraint of primaries. The FIST algorithm has been demonstrated as a faster alternative to the IRLS algorithm. In this paper we introduce the FIST algorithm to solve the filter coefficients in the limited supporting region of filters. Compared with the FIST based multichannel predictive deconvolution without the limited supporting region of filters the proposed method can reduce the computation burden effectively while achieving a similar accuracy. Additionally, the proposed method can better balance multiple removal and primary preservation than the traditional LS based multichannel predictive deconvolution and FIST based single channel predictive deconvolution. Synthetic and field data sets demonstrate the effectiveness of the proposed method.
The Mid-Term Efficacy and Safety of a Permanent Nitinol IVC Filter (TrapEase)
Liu, Wei Chiang; Choo, Sung Wook; Kim, Dong-Ik; Kim, Young Wook; Kim, Duk-Kyung; Shin, Sung Wook; Park, Kwang Bo; Jeon, Yong Hwan; Choo, In-Wook
2005-01-01
Objective 1) To evaluate the mid-term efficacy and safety of a permanent nitinol inferior vena cava (IVC) filter; 2) to evaluate filter effectiveness, filter stability and caval occlusion. Materials and Methods A prospective evaluation of the TrapEase IVC filter was performed on 42 patients (eight men, 34 women) ranging in age from 22 to 78 years (mean age 66 years). All patients were ill with a high risk of pulmonary embolism (PE). Indications for filter placement were: 1) deep vein thrombosis with recurrent thromboembolism; 2) and/or free-floating thrombus with contraindication to anticoagulation; and 3) complications in achieving adequate anticoagulation. Follow-up evaluations (mean: 15.4 months, range: 2 to 28 months) were performed at 6- and 12-month intervals after the procedure and included clinical histories, chart reviews, plain film, Doppler ultrasounds, and contrasted abdominal CT scans. Results In follow-up evaluations, the data analysis revealed no cases of symptomatic PE. There were no cases of filter migration, insertion site thrombosis, filter fracture, or vessel wall perforation. During the study, there was one case of filter thrombosis; early symptomatic thrombosis that was successfully treated in the hospital. Of the 42 subjects, eight died. These deaths were not related to the filter device or the implantation procedure, but to the underlying disease. Conclusion This study demonstrates that the TrapEase permanent IVC filter is a safe and an effective device with low complication rates and is best used in patients with thromboembolic disease with a high risk of PE. PMID:15968150
Engineering Filters for Reducing Spontaneous Emission in cQED
NASA Astrophysics Data System (ADS)
Bronn, Nicholas; Masluk, Nicholas; Srinivasan, Srikanth; Chow, Jerry; Abraham, David; Rothwell, Mary; Keefe, George; Gambetta, Jay; Steffen, Matthias; Lirakis, Chris
2014-03-01
Inserting a notch filter between a qubit and the external environment at the qubit frequency can significantly suppress spontaneous emission mediated by the cavity (``Purcell effect''). In order to realize this filtering in multi-qubit architectures, where space comes at a premium, we will present a filter with minimal space requirements. We acknowledge support from IARPA under contract W911NF-10-1-0324.
Ijadunola, Macellina Y; Ojo, Temitope O; Babatunde, Adelekan; Olatunji, Gbajumo J; Owolabi, Gbolagade K; Adewale, Ibiyemi A; Ifedayo, Ibukun F; Friday, Ijuewe S
2015-02-01
Street hawking is the commonest form of child labor in Nigeria. Although street hawking is very pervasive, there is the increasing need to fully understand its pattern and effects on those involved in hawking particularly adolescents who combine schooling with hawking. In Nigeria, data on the effects of street hawking on in-school adolescents are generally scanty. Therefore, the present study was undertaken in Ife Central Local Government Area (LGA) of Osun State, Nigeria to assess the pattern, determinants of street hawking among in-school adolescents and its effect on school performance. A cross-sectional study of 435 adolescents (aged 10-19) attending public secondary schools was done. Data were collected using facilitated self-administered questionnaires alongside a review of class records. Appropriate statistical analysis including multiple regression was done. Results showed mean age of respondents to be 14.6±2.1 years with prevalence of street hawking at 37.2%. Early adolescents (10-13 years) were more likely to engage in street hawking compared to their counterparts in late adolescence (aged 17-19). Female adolescents and students of trading mothers were significantly more likely to engage in street hawking. Respondents engaged in street hawking were significantly more likely to have failed the last academic term examination. The findings from this study will be useful for stakeholders as they develop policies and programmes to address the challenge of street hawking among adolescent school goers.
Photodegradation of avobenzone: stabilization effect of antioxidants.
Afonso, S; Horita, K; Sousa e Silva, J P; Almeida, I F; Amaral, M H; Lobão, P A; Costa, P C; Miranda, Margarida S; Esteves da Silva, Joaquim C G; Sousa Lobo, J M
2014-11-01
Avobenzone is one of the most common UVA-filters in sunscreens, and is known to be photounstable. Some of the strategies used to stabilize this filter present some drawbacks like photosensitization reactions. Antioxidants are widely used as cosmetic ingredients that prevent photoageing and complement the photoprotection offered by the UV-filters preventing or reducing photogenerated reactive species. The purpose of this work was to study the effect of antioxidants in the photostabilization of avobenzone. The filter dissolved in dimethyl sulfoxide or incorporated in a sunscreen formulation was irradiated with simulated solar radiation (750 W/m(2)). The tested antioxidants were vitamin C, vitamin E, and ubiquinone. The area under the curve of the absorption spectrum for UVA range and the sun protection factor (SPF) were calculated. Vitamin E (1:2), vitamin C (1:0.5) and ubiquinone (1:0.5) were the more effective concentrations increasing the photostability of avobenzone. In sunscreen formulations, the most effective photostabilizer was ubiquinone which also promoted an increase in SPF. This knowledge is important to improve effectiveness of sunscreen formulation. Antioxidants can be valuable ingredients for sunscreens with a triple activity of filter stabilization, SPF boosting and photoageing prevention. Copyright © 2014 Elsevier B.V. All rights reserved.
Wagner, Florian B; Nielsen, Peter Borch; Boe-Hansen, Rasmus; Albrechtsen, Hans-Jørgen
2016-05-15
Incomplete nitrification in biological filters during drinking water treatment is problematic, as it compromises drinking water quality. Nitrification problems can be caused by a lack of nutrients for the nitrifying microorganisms. Since copper is an important element in one of the essential enzymes in nitrification, we investigated the effect of copper dosing on nitrification in different biological rapid sand filters treating groundwater. A lab-scale column assay with filter material from a water works demonstrated that addition of a trace metal mixture, including copper, increased ammonium removal compared to a control without addition. Subsequently, another water works was investigated in full-scale, where copper influent concentrations were below 0.05 μg Cu L(-1) and nitrification was incomplete. Copper dosing of less than 5 μg Cu L(-1) to a full-scale filter stimulated ammonium removal within one day, and doubled the filter's removal from 0.22 to 0.46 g NH4-N m(-3) filter material h(-1) within 20 days. The location of ammonium and nitrite oxidation shifted upwards in the filter, with an almost 14-fold increase in ammonium removal rate in the filter's top 10 cm, within 57 days of dosing. To study the persistence of the stimulation, copper was dosed to another filter at the water works for 42 days. After dosing was stopped, nitrification remained complete for at least 238 days. Filter effluent concentrations of up to 1.3 μg Cu L(-1) confirmed that copper fully penetrated the filters, and determination of copper content on filter media revealed a buildup of copper during dosing. The amount of copper stored on filter material gradually decreased after dosing stopped; however at a slower rate than it accumulated. Continuous detection of copper in the filter effluent confirmed a release of copper to the bulk phase. Overall, copper dosing to poorly performing biological rapid sand filters increased ammonium removal rates significantly, achieving effluent concentrations of below 0.01 mg NH4-N L(-1), and had a long-term effect on nitrification performance. Copyright © 2016 Elsevier Ltd. All rights reserved.
Leukocyte-reduced blood components: patient benefits and practical applications.
Higgins, V L
1996-05-01
To review the various types of filters used for red blood cell and platelet transfusions and to explain the trend in the use of leukocyte removal filters, practical information about their use, considerations in the selection of a filtration method, and cost-effectiveness issues. Published articles, books, and the author's experience. Leukocyte removal filters are used to reduce complications associated with transfused white blood cells that are contained in units of red blood cells and platelets. These complications include nonhemolytic febrile transfusion reactions (NHFTRs), alloimmunization and refractoriness to platelet transfusion, transfusion-transmitted cytomegalovirus (CMV), and immunomodulation. Leukocyte removal filters may be used at the bedside, in a hospital blood bank, or in a blood collection center. Factors that affect the flow rate of these filters include the variations in the blood component, the equipment used, and filter priming. Studies on the cost-effectiveness of using leukocyte-reduced blood components demonstrate savings based on the reduction of NHFTRs, reduction in the number of blood components used, and the use of filtered blood components as the equivalent of CMV seronegative-screened products. The use of leukocyte-reduced blood components significantly diminishes or prevents many of the adverse transfusion reactions associated with donor white blood cells. Leukocyte removal filters are cost-effective, and filters should be selected based on their ability to consistently achieve low leukocyte residual levels as well as their ease of use. Physicians may order leukocyte-reduced blood components for specific patients, or the components may be used because of an established institutional transfusion policy. Nurses often participate in deciding on a filtration method, primarily based on ease of use. Understanding the considerations in selecting a filtration method will help nurses make appropriate decisions to ensure quality patient care.
Dynamic State Estimation of Power Systems With Quantization Effects: A Recursive Filter Approach.
Hu, Liang; Wang, Zidong; Liu, Xiaohui
2016-08-01
In this paper, a recursive filter algorithm is developed to deal with the state estimation problem for power systems with quantized nonlinear measurements. The measurements from both the remote terminal units and the phasor measurement unit are subject to quantizations described by a logarithmic quantizer. Attention is focused on the design of a recursive filter such that, in the simultaneous presence of nonlinear measurements and quantization effects, an upper bound for the estimation error covariance is guaranteed and subsequently minimized. Instead of using the traditional approximation methods in nonlinear estimation that simply ignore the linearization errors, we treat both the linearization and quantization errors as norm-bounded uncertainties in the algorithm development so as to improve the performance of the estimator. For the power system with such kind of introduced uncertainties, a filter is designed in the framework of robust recursive estimation, and the developed filter algorithm is tested on the IEEE benchmark power system to demonstrate its effectiveness.
Enhancing Spin Filters by Use of Bulk Inversion Asymmetry
NASA Technical Reports Server (NTRS)
Ting, David; Cartoixa,Xavier
2007-01-01
Theoretical calculations have shown that the degrees of spin polarization in proposed nonmagnetic semiconductor resonant tunneling spin filters could be increased through exploitation of bulk inversion asymmetry (BIA). These enhancements would be effected through suitable orientation of spin collectors (or spin-polarization- inducing lateral electric fields), as described below. Spin filters -- more precisely, sources of spin-polarized electron currents -- have been sought for research on, and development of, the emerging technological discipline of spintronics (spin-transport electronics). The proposed spin filters were to be based on the Rashba effect, which is an energy splitting of what would otherwise be degenerate quantum states, caused by a spinorbit interaction in conjunction with a structural-inversion asymmetry (SIA) in the presence of interfacial electric fields in a semiconductor heterostructure. The magnitude of the energy split is proportional to the electron wave number. In a spin filter, the spin-polarized currents produced by the Rashba effect would be extracted by quantum-mechanical resonant tunneling.
Effect of ECG filter settings on J-waves.
Nakagawa, Mikiko; Tsunemitsu, Chie; Katoh, Sayo; Kamiyama, Yukari; Sano, Nario; Ezaki, Kaori; Miyazaki, Hiroko; Teshima, Yasushi; Yufu, Kunio; Takahashi, Naohiko; Saikawa, Tetsunori
2014-01-01
While J-waves were observed in healthy populations, variations in their reported incidence may be partly explicable by the ECG filter setting. We obtained resting 12-lead ECG recordings in 665 consecutive patients and enrolled 112 (56 men, 56 women, mean age 59.3±16.1years) who manifested J-waves on ECGs acquired with a 150-Hz low-pass filter. We then studied the J-waves on individual ECGs to look for morphological changes when 25-, 35-, 75-, 100-, and 150Hz filters were used. The notching observed with the 150-Hz filter changed to slurring (42%) or was eliminated (28%) with the 25-Hz filter. Similarly, the slurring seen with the 150-Hz filter was eliminated on 71% of ECGs recorded with the 25-Hz filter. The amplitude of J-waves was significantly lower with 25- and 35-Hz than 75-, 100-, and 150-Hz filters (p<0.0001). The ECG filter setting significantly affects the J-wave morphology. © 2013.
Evaluation of a Shaker Dust Collector for Use in a Recirculating Ventilation System
Sawvel, Russell A.; Park, Jae Hong; Anthony, T. Renée
2016-01-01
General ventilation with recirculated air may be cost-effective to control the concentration of low-toxicity, contaminants in workplaces with diffuse, dusty operations, such as in agriculture. Such systems are, however, rarely adopted with little evidence showing improved air quality and ability to operate under harsh conditions. The goal of this work was to examine the initial and long-term performance of a fabric-filter shaker dust collector (SDC) in laboratory tests and as deployed within a recirculating ventilation system in an agricultural building. In laboratory tests, collection efficiency and pressure drop were tracked over several filter loading cycles, and the recovery of filter capacity (pressure drop) from filter shaking was examined. Collection efficiencies of particles larger than 5 μm was high (>95%) even when the filter was pristine, showing effective collection of large particles that dominate inhalable concentrations typical of agricultural dusts. For respirable-sized particles, collection efficiencies were low when the filter was pristine (e.g., 27% for 1 μm) but much higher when a dust cake developed on the filter (>99% for all size particles), even after shaking (e.g., 90% for 1 μm). The first shake of a filter was observed to recovery a substantial fraction of filter capacity, with subsequent shakes providing little benefit. In field tests, the SDC performed effectively over a period of three months in winter when incorporated in a recirculating ventilation system of a swine farrowing room. Trends in collection efficiency and pressure drop with loading were similar to those observed in the laboratory with overall collection efficiencies high (>80%) when pressure drop exceeded 230 Pa, or 23% of the maximum loading recommended by the manufacturer. This work shows that the SDC can function effectively over the harsh winter in swine rearing operations. Together with findings of improved air quality in the farrowing room reported in a companion manuscript, this article provides evidence that an SDC represents a cost-effective solution to improve air quality in agricultural settings. PMID:25955507
NASA Astrophysics Data System (ADS)
Wallace, Lance A.; Emmerich, Steven J.; Howard-Reed, Cynthia
Airborne particles are implicated in morbidity and mortality of certain high-risk subpopulations. Exposure to particles occurs mostly indoors, where a main removal mechanism is deposition to surfaces. Deposition can be affected by the use of forced-air circulation through ducts or by air filters. In this study, we calculate the deposition rates of particles in an occupied house due to forced-air circulation and the use of in-duct filters such as electrostatic precipitators (ESP) and fibrous mechanical filters (MECH). Deposition rates are calculated for 128 size categories ranging from 0.01 to 2.5 μm. More than 110 separate "events" (mostly cooking, candle burning, and pouring kitty litter) were used to calculate deposition rates for four conditions: fan off, fan on, MECH installed, ESP installed. For all cases, deposition rates varied in a "U"-shaped distribution with the minimum occurring near 0.1 μm, as predicted by theory. The use of the central fan with no filter or with a standard furnace filter increased deposition rates by amounts on the order of 0.1-0.5 h -1. The MECH increased deposition rates by up to 2 h -1 for ultrafine and fine particles but was ineffective for particles in the 0.1-0.5 μm range. The ESP increased deposition rates by 2-3 h -1 and was effective for all sizes. However, the ESP lost efficiency after several weeks and needed regular cleaning to maintain its effectiveness. A reduction of particle levels by 50% or more could be achieved by use of the ESP when operating properly. Since the use of fans and filters reduces particle concentrations from both indoor and outdoor sources, it is more effective than the alternative approach of reducing ventilation by closing windows or insulating homes more tightly. For persons at risk, use of an air filter may be an effective method of reducing exposure to particles.
Assessing the anti-fungal efficiency of filters coated with zinc oxide nanoparticles
NASA Astrophysics Data System (ADS)
Decelis, Stephen; Sardella, Davide; Triganza, Thomas; Brincat, Jean-Pierre; Gatt, Ruben; Valdramidis, Vasilis P.
2017-05-01
Air filters support fungal growth, leading to generation of conidia and volatile organic compounds, causing allergies, infections and food spoilage. Filters that inhibit fungi are therefore necessary. Zinc oxide (ZnO) nanoparticles have anti-fungal properties and therefore are good candidates for inhibiting growth. Two concentrations (0.012 M and 0.12 M) were used to coat two types of filters (melt-blown and needle-punched) for three different periods (0.5, 5 and 50 min). Rhizopus stolonifer and Penicillium expansum isolated from spoiled pears were used as test organisms. Conidial suspensions of 105 to 103 spores ml-1 were prepared in Sabouraud dextrose agar at 50°C, and a modified slide-culture technique was used to test the anti-fungal properties of the filters. Penicillium expansum was the more sensitive organism, with inhibition at 0.012 M at only 0.5 min coating time on the needle-punched filter. The longer the coating time, the more effective inhibition was for both organisms. Furthermore, it was also determined that the coating process had only a slight effect on the Young's Moduli of the needle-punched filters, while the Young's Moduli of the melt-blown filters is more susceptible to the coating method. This work contributes to the assessment of the efficacy of filter coating with ZnO nanopaticles aimed at inhibiting fungal growth.
Assessing the anti-fungal efficiency of filters coated with zinc oxide nanoparticles
Decelis, Stephen; Sardella, Davide; Triganza, Thomas; Brincat, Jean-Pierre; Gatt, Ruben
2017-01-01
Air filters support fungal growth, leading to generation of conidia and volatile organic compounds, causing allergies, infections and food spoilage. Filters that inhibit fungi are therefore necessary. Zinc oxide (ZnO) nanoparticles have anti-fungal properties and therefore are good candidates for inhibiting growth. Two concentrations (0.012 M and 0.12 M) were used to coat two types of filters (melt-blown and needle-punched) for three different periods (0.5, 5 and 50 min). Rhizopus stolonifer and Penicillium expansum isolated from spoiled pears were used as test organisms. Conidial suspensions of 105 to 103 spores ml−1 were prepared in Sabouraud dextrose agar at 50°C, and a modified slide-culture technique was used to test the anti-fungal properties of the filters. Penicillium expansum was the more sensitive organism, with inhibition at 0.012 M at only 0.5 min coating time on the needle-punched filter. The longer the coating time, the more effective inhibition was for both organisms. Furthermore, it was also determined that the coating process had only a slight effect on the Young's Moduli of the needle-punched filters, while the Young's Moduli of the melt-blown filters is more susceptible to the coating method. This work contributes to the assessment of the efficacy of filter coating with ZnO nanopaticles aimed at inhibiting fungal growth. PMID:28572995
Assessing the anti-fungal efficiency of filters coated with zinc oxide nanoparticles.
Decelis, Stephen; Sardella, Davide; Triganza, Thomas; Brincat, Jean-Pierre; Gatt, Ruben; Valdramidis, Vasilis P
2017-05-01
Air filters support fungal growth, leading to generation of conidia and volatile organic compounds, causing allergies, infections and food spoilage. Filters that inhibit fungi are therefore necessary. Zinc oxide (ZnO) nanoparticles have anti-fungal properties and therefore are good candidates for inhibiting growth. Two concentrations (0.012 M and 0.12 M) were used to coat two types of filters (melt-blown and needle-punched) for three different periods (0.5, 5 and 50 min). Rhizopus stolonifer and Penicillium expansum isolated from spoiled pears were used as test organisms. Conidial suspensions of 10 5 to 10 3 spores ml -1 were prepared in Sabouraud dextrose agar at 50°C, and a modified slide-culture technique was used to test the anti-fungal properties of the filters. Penicillium expansum was the more sensitive organism, with inhibition at 0.012 M at only 0.5 min coating time on the needle-punched filter. The longer the coating time, the more effective inhibition was for both organisms. Furthermore, it was also determined that the coating process had only a slight effect on the Young's Moduli of the needle-punched filters, while the Young's Moduli of the melt-blown filters is more susceptible to the coating method. This work contributes to the assessment of the efficacy of filter coating with ZnO nanopaticles aimed at inhibiting fungal growth.
Radical protection by differently composed creams in the UV/VIS and IR spectral ranges.
Meinke, Martina C; Syring, Felicia; Schanzer, Sabine; Haag, Stefan F; Graf, Rüdiger; Loch, Manuela; Gersonde, Ingo; Groth, Norbert; Pflücker, Frank; Lademann, Jürgen
2013-01-01
Modern sunscreens are well suited to provide sufficient protection in the UV range because the filter substances absorb or scatter UV radiation. Although up to 50% of radicals are formed in the visible and infrared spectral range during solar radiation protection strategies are not provided in this range. Previous investigations of commercially available products have shown that in addition to physical filters, antioxidants (AO) are necessary to provide protective effects in the infrared range by neutralizing already formed radicals. In this study, the efficacy of filter substances and AO to reduce radical formation in both spectral ranges was investigated after UV/VIS or IR irradiation. Optical properties and radical protection were determined for the investigated creams. It was found that organic UV filters lower radical formation in the UV/VIS range to 35% compared to untreated skin, independent of the presence of AO. Further reduction to 14% was reached by addition of 2% physical filters, whereas physical filters alone were ineffective in the UV/VIS range due to the low concentration. In contrast, this filter type reduced radical formation in the IR range significantly to 65%; similar effects were aroused after application of AO. Sunscreens which contain organic UV filters, physical filters and AO ensure protection in the complete solar spectrum. © 2013 The American Society of Photobiology.
Effects of spatial frequency content on classification of face gender and expression.
Aguado, Luis; Serrano-Pedraza, Ignacio; Rodríguez, Sonia; Román, Francisco J
2010-11-01
The role of different spatial frequency bands on face gender and expression categorization was studied in three experiments. Accuracy and reaction time were measured for unfiltered, low-pass (cut-off frequency of 1 cycle/deg) and high-pass (cutoff frequency of 3 cycles/deg) filtered faces. Filtered and unfiltered faces were equated in root-mean-squared contrast. For low-pass filtered faces reaction times were higher than unfiltered and high-pass filtered faces in both categorization tasks. In the expression task, these results were obtained with expressive faces presented in isolation (Experiment 1) and also with neutral-expressive dynamic sequences where each expressive face was preceded by a briefly presented neutral version of the same face (Experiment 2). For high-pass filtered faces different effects were observed on gender and expression categorization. While both speed and accuracy of gender categorization were reduced comparing to unfiltered faces, the efficiency of expression classification remained similar. Finally, we found no differences between expressive and non expressive faces in the effects of spatial frequency filtering on gender categorization (Experiment 3). These results show a common role of information from the high spatial frequency band in the categorization of face gender and expression.
LLSURE: local linear SURE-based edge-preserving image filtering.
Qiu, Tianshuang; Wang, Aiqi; Yu, Nannan; Song, Aimin
2013-01-01
In this paper, we propose a novel approach for performing high-quality edge-preserving image filtering. Based on a local linear model and using the principle of Stein's unbiased risk estimate as an estimator for the mean squared error from the noisy image only, we derive a simple explicit image filter which can filter out noise while preserving edges and fine-scale details. Moreover, this filter has a fast and exact linear-time algorithm whose computational complexity is independent of the filtering kernel size; thus, it can be applied to real time image processing tasks. The experimental results demonstrate the effectiveness of the new filter for various computer vision applications, including noise reduction, detail smoothing and enhancement, high dynamic range compression, and flash/no-flash denoising.
NASA Technical Reports Server (NTRS)
Hawkins, Gary J.; Seeley, John S.; Hunneman, Roger
1992-01-01
Infrared optical multilayer filters and materials were exposed to the space environment of low Earth orbit on LDEF. The effects are summarized of that environment on the physical and optical properties of the filters and materials flown.
Polymer based resonant waveguide grating photonic filter with on-chip thermal tuning
NASA Astrophysics Data System (ADS)
Chaudhuri, Ritesh Ray; Enemuo, Amarachukwu N.; Song, Youngsik; Seo, Sang-Woo
2018-07-01
In this paper, we present the development of a multilayer polymer resonant waveguide grating (RWG)-based optical filter with an integrated microheater for on-chip thermal spectral tuning. RWG optical filter is fabricated using polymer-based materials. Therefore, its integration can be applied to different material platforms. Typical RWG structure is sensitive to back optical reflection from the structures below. To reduce the effect of back reflection from the metal heater and improve the quality of the integrated RWG filter output, an intermediate absorption layer was implemented utilizing an epoxy based carbon coating. This approach effectively suppresses the background noise in the RWG characteristics. The central wavelength of the reported filter was designed around 1550 nm. Experimentally, wavelength tuning of 21.96 nm was achieved for operating temperature range of 81 °C with approximately 150mW power consumption. Based on the layer-by-layer fabrication approach, the presented thermally tunable RWG filter on a chip has potential for use in low cost hybrid communication systems and spectral sensing applications.
Effects of Ultra-Clean and centrifugal filtration on rolling-element bearing life
NASA Technical Reports Server (NTRS)
Loewenthal, S. H.; Moyer, D. W.; Needelman, W. M.
1981-01-01
Fatigue tests were conducted on groups of 65-millimeter bore diameter deep-groove ball bearings in a MIL-L-23699 lubricant under two levels of filtration. In one test series, the oil cleanliness was maintained at an exceptionally high level (better than a class "000" per NAS 1638) with a 3 micron absolute barrier filter. These tests were intended to determine the "upper limit" in bearing life under the strictest possible lubricant cleanliness conditions. In the tests using a centrifugal oil filter, contaminants of the type found in aircraft engine filters were injected into the filters' supply line at 125 milligrams per bearing-hour. "Ultra-clean" lubrication produced bearing fatigue lives that were approximately twice that obtained in previous tests with contaminated oil using 3 micron absolute filtration and approximately three times that obtained with 49 micron filtration. It was also observed that the centrifugal oil filter had approximately the same effectiveness as a 30 micron absolute filter in preventing bearing surface damage.
Signal identification in acoustic emission monitoring of fatigue cracking in steel bridges
NASA Astrophysics Data System (ADS)
Yu, Jianguo P.; Ziehl, Paul; Pollock, Adrian
2012-04-01
Signal identification including noise filtering and reduction of acquired signals is needed to achieve efficient and accurate data interpretation for remote acoustic emission (AE) monitoring of in-service steel bridges. Noise filtering may ensure that genuine hits from crack growth are involved in the estimation of fatigue damage and remaining fatigue life. Reduction of the data quantity is desirable for the sensing system to conserve energy in the data transmission and processing procedures. Identification and categorization of acquired signals is a promising approach to effectively filter and reduce AE data in the application of bridge monitoring. In this study an investigation on waveform features (time domain and frequency domain) and relevant filters is carried out using the results from AE monitored fatigue tests. It is verified that duration-amplitude (D-A) filters are effective to discriminate against noise for results of steel fatigue tests. The study is helpful to find an appropriate AE data filtering protocol for field implementations.
Spectral filtering for plant production
DOE Office of Scientific and Technical Information (OSTI.GOV)
Young, R.E.; McMahon, M.J.; Rajapakse, N.C.
1994-12-31
Research to date suggests that spectral filtering can be an effective alternative to chemical growth regulators for altering plant development. If properly implemented, it can be nonchemical and environmentally friendly. The aqueous CuSO{sub 4}, and CuCl{sub 2} solutions in channelled plastic panels have been shown to be effective filters, but they can be highly toxic if the solutions contact plants. Some studies suggest that spectral filtration limited to short EOD intervals can also alter plant development. Future research should be directed toward confirmation of the influence of spectral filters and exposure times on a broader range of plant species andmore » cultivars. Efforts should also be made to identify non-noxious alternatives to aqueous copper solutions and/or to incorporate these chemicals permanently into plastic films and panels that can be used in greenhouse construction. It would also be informative to study the impacts of spectral filters on insect and microbal populations in plant growth facilities. The economic impacts of spectral filtering techniques should be assessed for each delivery methodology.« less
Uchida, Yumiko; Morimoto, Yukihiro; Uchiike, Takao; Kamamoto, Tomoyuki; Hayashi, Tamaki; Arai, Ikuyo; Nishikubo, Toshiya; Takahashi, Yukihiro
2015-07-01
Phototherapy using blue light-emitting diodes (LED) is effective against neonatal jaundice. However, green light phototherapy also reduces unconjugated jaundice. We aimed to determine whether mixed blue and green light can relieve jaundice with minimal oxidative stress as effectively as either blue or green light alone in a rat model. Gunn rats were exposed to phototherapy with blue (420-520 nm), filtered blue (FB; 440-520 nm without<440-nm wavelengths, FB50 (half the irradiance of filtered blue), mixed (filtered 50% blue and 50% green), and green (490-590 nm) LED irradiation for 24h. The effects of phototherapy are expressed as ratios of serum total (TB) and unbound (UB) bilirubin before and after exposure to each LED. Urinary 8-hydroxy-2'-deoxyguanosine (8-OHdG) was measured by HPLC before and after exposure to each LED to determine photo-oxidative stress. Values < 1.00 indicate effective phototherapy. The ratios of TB and UB were decreased to 0.85, 0.89, 1.07, 0.90, and 1.04, and 0.85, 0.94, 0.93, 0.89, and 1.09 after exposure to blue, filtered blue, FB50, and filtered blue mixed with green LED, respectively. In contrast, urinary 8-OHdG increased to 2.03, 1.25, 0.96, 1.36, 1.31, and 1.23 after exposure to blue, filtered blue, FB50, mixed, green LED, and control, indicating side-effects (> 1.00), respectively. Blue plus green phototherapy is as effective as blue phototherapy and it attenuates irradiation-induced oxidative stress. Combined blue and green spectra might be effective against neonatal hyperbilirubinemia. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.
Chatelain, E; Gabard, B
2001-09-01
It is now well documented that chronic UVA exposure induces damage to human skin. Therefore, modern sunscreens should not only provide protection from both UVB and UVA radiation but also maintain this protection during the entire period of exposure to the sun. UVA filters, however, are rare and not sufficiently photostable. We investigated the effect of the introduction of a new UV filter, bis-ethylhexyloxyphenol methoxyphenyl triazine (Tinosorb S), in oil in water sunscreen formulations on the photostability of butyl methoxydibenzoylmethane (Avobenzone [AVB]) after irradiation with an optically filtered Xenon arc source (UV irradiance adjusted at 1 mean effective dose [MED]/min). With spectrophotometrical methods to assess the sun protection factor (SPF) and UVA ratio and chromatographical methods to determine the amount of UV filters recovered after irradiation we showed that Tinosorb S prevented the photodegradation of AVB in a concentration-dependent way, leading to a sustained SPF and UVA ratio even after irradiation with doses of up to 30 MED. Since AVB was shown to destabilize ethylhexyl methoxycinnamate (EHM) we tested the effect of Tinosorb S in sunscreens containing this UV filter combination. Here too Tinosorb S showed photoprotective properties toward both UV filters. Thus, Tinosorb S can be used successfully to improve the photostability and efficiency of sunscreens containing AVB and EHM.
Carrasco-Turigas, Glòria; Villanueva, Cristina M.; Goñi, Fernando; Rantakokko, Panu; Nieuwenhuijsen, Mark J.
2013-01-01
Disinfection by-products (DBPs) are ubiquitous contaminants in tap drinking water with the potential to produce adverse health effects. Filtering and boiling tap water can lead to changes in the DBP concentrations and modify the exposure through ingestion. Changes in the concentration of 4 individual trihalomethanes (THM4) (chloroform (TCM), bromodichloromethane (BDCM), dibromochloromethane (DBCM), and bromoform (TBM)), MX, and bromate were tested when boiling and filtering high bromine-containing tap water from Barcelona. For filtering, we used a pitcher-type filter and a household reverse osmosis filter; for boiling, an electric kettle, a saucepan, and a microwave were used. Samples were taken before and after each treatment to determine the change in the DBP concentration. pH, conductivity, and free/total chlorine were also measured. A large decrease of THM4 (from 48% to 97%) and MX concentrations was observed for all experiments. Bromine-containing trihalomethanes were mostly eliminated when filtering while chloroform when boiling. There was a large decrease in the concentration of bromate with reverse osmosis, but there was a little effect in the other experiments. These findings suggest that the exposure to THM4 and MX through ingestion is reduced when using these household appliances, while the decrease of bromate is device dependent. This needs to be considered in the exposure assessment of the epidemiological studies. PMID:23476675
The Joint Adaptive Kalman Filter (JAKF) for Vehicle Motion State Estimation.
Gao, Siwei; Liu, Yanheng; Wang, Jian; Deng, Weiwen; Oh, Heekuck
2016-07-16
This paper proposes a multi-sensory Joint Adaptive Kalman Filter (JAKF) through extending innovation-based adaptive estimation (IAE) to estimate the motion state of the moving vehicles ahead. JAKF views Lidar and Radar data as the source of the local filters, which aims to adaptively adjust the measurement noise variance-covariance (V-C) matrix 'R' and the system noise V-C matrix 'Q'. Then, the global filter uses R to calculate the information allocation factor 'β' for data fusion. Finally, the global filter completes optimal data fusion and feeds back to the local filters to improve the measurement accuracy of the local filters. Extensive simulation and experimental results show that the JAKF has better adaptive ability and fault tolerance. JAKF enables one to bridge the gap of the accuracy difference of various sensors to improve the integral filtering effectivity. If any sensor breaks down, the filtered results of JAKF still can maintain a stable convergence rate. Moreover, the JAKF outperforms the conventional Kalman filter (CKF) and the innovation-based adaptive Kalman filter (IAKF) with respect to the accuracy of displacement, velocity, and acceleration, respectively.
? filtering for stochastic systems driven by Poisson processes
NASA Astrophysics Data System (ADS)
Song, Bo; Wu, Zheng-Guang; Park, Ju H.; Shi, Guodong; Zhang, Ya
2015-01-01
This paper investigates the ? filtering problem for stochastic systems driven by Poisson processes. By utilising the martingale theory such as the predictable projection operator and the dual predictable projection operator, this paper transforms the expectation of stochastic integral with respect to the Poisson process into the expectation of Lebesgue integral. Then, based on this, this paper designs an ? filter such that the filtering error system is mean-square asymptotically stable and satisfies a prescribed ? performance level. Finally, a simulation example is given to illustrate the effectiveness of the proposed filtering scheme.
Robust Lee local statistic filter for removal of mixed multiplicative and impulse noise
NASA Astrophysics Data System (ADS)
Ponomarenko, Nikolay N.; Lukin, Vladimir V.; Egiazarian, Karen O.; Astola, Jaakko T.
2004-05-01
A robust version of Lee local statistic filter able to effectively suppress the mixed multiplicative and impulse noise in images is proposed. The performance of the proposed modification is studied for a set of test images, several values of multiplicative noise variance, Gaussian and Rayleigh probability density functions of speckle, and different characteris-tics of impulse noise. The advantages of the designed filter in comparison to the conventional Lee local statistic filter and some other filters able to cope with mixed multiplicative+impulse noise are demonstrated.
Effect of causal and acausal filters on elastic and inelastic response spectra
Boore, D.M.; Akkar, Sinan
2003-01-01
With increasing interest in displacement spectra and long-period motions, it is important to check the sensitivity of both elastic and inelastic response spectra to the filtering that is often necessary to remove long period artifacts, even from many modern digital recordings. Using two records of very different character from the M=7.1, 1999 Hector Mine, California, earthquake, we find that the response spectra can be sensitive to the corner periods used in causal filtering, even for oscillator periods much less than the filter corner periods. The effect is most pronounced for inelastic response spectra, where the ratio of response spectra computed from accelerations filtered at 25 and 200 sec can be close to a factor of 2 for oscillator periods less than 5 sec. Published in 2003 by John Wiley and Sons, Ltd.
An approach of point cloud denoising based on improved bilateral filtering
NASA Astrophysics Data System (ADS)
Zheng, Zeling; Jia, Songmin; Zhang, Guoliang; Li, Xiuzhi; Zhang, Xiangyin
2018-04-01
An omnidirectional mobile platform is designed for building point cloud based on an improved filtering algorithm which is employed to handle the depth image. First, the mobile platform can move flexibly and the control interface is convenient to control. Then, because the traditional bilateral filtering algorithm is time-consuming and inefficient, a novel method is proposed which called local bilateral filtering (LBF). LBF is applied to process depth image obtained by the Kinect sensor. The results show that the effect of removing noise is improved comparing with the bilateral filtering. In the condition of off-line, the color images and processed images are used to build point clouds. Finally, experimental results demonstrate that our method improves the speed of processing time of depth image and the effect of point cloud which has been built.
Pompei, Caroline M E; Ciric, Lena; Canales, Melisa; Karu, Kersti; Vieira, Eny M; Campos, Luiza C
2017-03-01
Removal of pharmaceuticals and personal care products (PPCPs) from drinking water is usually enhanced by advanced oxidation which is not affordable in low income countries. Slow sand filtration has been found to be capable of removing anti-inflammatory compounds, and its low maintenance costs and easy operation make it an attractive technology for treating drinking water in many parts of the world. In addition, slow sand filters can be used at both large and household scales. The biofilm (i.e. schmutzdecke) developed on the top of the sand and within the upper layers of the sand is acknowledged to be responsible for the water purification. However, it is possible that the PPCPs may affect the schmutzdecke development and microbial community within the filters, and consequently the performance of the filter. This study investigated two household slow sand filters (for water purification) operated intermittently with and without contamination by six PPCPs. Eleven parameters were monitored in the affluent and effluent water, including bacterial species present and schmutzdecke biomass development. Results demonstrated that the household slow sand filter performance was not affected by the 2μgL -1 of PPCPs in the water. There was no significant difference between filters for total coliforms and E. coli removal, but there was considerable difference between sampling times. Biomass considerably increased with the number of filtrations in both filters and there was no significant difference between filter biomass. However, it was found that more bacterial species were present in the period with no contamination than during the contamination period. Bacillus anthracis and Exiguobacterium sp. showed to be resistant to the effects of the PPCPs. These suggest there are effects of PPCPs on bacterial species within the filter. However, the effect of the PPCPs on biomass was not conclusive in this study and needs to be further investigated. Copyright © 2016 Elsevier B.V. All rights reserved.
Effect of NPK fertilizer on chemical composition of pumpkin (Cucurbita pepo Linn.) seeds.
Oloyede, F M; Obisesan, I O; Agbaje, G O; Obuotor, E M
2012-01-01
An investigation of the proximate composition and antioxidant profile of pumpkin seeds obtained from different levels of NPK 15 : 15 : 15 compound fertilizer application at the Obafemi Awolowo University, Ile-Ife, Nigeria was carried out. Pumpkin seeds were grown in 2010 for two cropping seasons (May to August and August to November), and the following fertilizer rates were applied: 0, 50, 100, 150, 200, and 250 kg/ha. Standard analytical methods were used to determine protein, crude fibre, ash, fat, carbohydrate, antioxidant activities, phenol, flavonoid, proanthocyanidin, and anthocyanin. The highest concentrations of the proximate and antioxidants analysed were found from the seeds of control and those treated with lower NPK rates. The mean protein, ash, crude fibre, and carbohydrate values of pumpkin seeds at zero to 100 kg NPK/ha were 27%, 1.56%, 0.56%, and 11.7% respectively. At these same levels of fertilizer, pumpkin seed oil yield was 59%. Antioxidant activities ranged from 89.9 to 90.4% while total phenol was 47 mg/100 g. Except for carbohydrate, the % concentration of nutrients and antioxidants in pumpkin seeds was significantly (P = 0.05) depressed with fertilizer rates above 100 g/ha.
Thermal management in inertial fusion energy slab amplifiers
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sutton, S.B.; Albrecht, G.F.
As the technology associated with the development of solid-state drivers for inertial fusion energy (IFE) has evolved, increased emphasis has been placed on the development of an efficient approach for managing the waste heat generated in the laser media. This paper addresses the technical issues associated with the gas cooling of large aperture slabs, where the laser beam propagates through the cooling fluid. It is shown that the major consequence of proper thermal management is the introduction of simple wedge, or beam steering, into the system. Achieving proper thermal management requires careful consideration of the geometry, cooling fluid characteristics, coolingmore » flow characteristics, as well as the thermal/mechanical/optical characteristics of the laser media. Particularly important are the effects of cooling rate variation and turbulent scattering on the system optical performance. Helium is shown to have an overwhelming advantage with respect to turbulent scattering losses. To mitigate cooling rate variations, the authors introduce the concept of flow conditioning. Finally, optical path length variations across the aperture are calculated. A comparison of two laser materials (S-FAP and YAG) shows the benefit of a nearly a-thermal material on optical variations in the system.« less
Modeling vegetative filter performance with VFSMOD
Matthew J. Helmers; Dean E. Eisenhauer; Michael G. Dosskey; Thomas G. Franti
2002-01-01
The model VFSMOD was used to investigate the effect of varying watershed characteristics and buffer dimensions on the sediment trapping efficiency of vegetative filters. This investigation allows for a better understanding of how watershed characteristics, buffer dimensions, and storm characteristics impact the performance of vegetative filters. Using VFSMOD,...
EFFECT OF ANAEROBIOSIS ON FILTER MEDIA POLLUTANT RETENTION
One of the primary problems with downflow filtration of stormwater runoff is the clogging of the filter prior to the medium's exhaustion of its chemical capacity. Upflow filtration using a siphon control may be a possibility for improving the life of the filters. However, for upf...
2011-12-30
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Assessment of intermittently loaded woodchip and sand filters to treat dairy soiled water.
Murnane, J G; Brennan, R B; Healy, M G; Fenton, O
2016-10-15
Land application of dairy soiled water (DSW) is expensive relative to its nutrient replacement value. The use of aerobic filters is an effective alternative method of treatment and potentially allows the final effluent to be reused on the farm. Knowledge gaps exist concerning the optimal design and operation of filters for the treatment of DSW. To address this, 18 laboratory-scale filters, with depths of either 0.6 m or 1 m, were intermittently loaded with DSW over periods of up to 220 days to evaluate the impacts of depth (0.6 m versus 1 m), organic loading rates (OLRs) (50 versus 155 g COD m(-2) d(-1)), and media type (woodchip versus sand) on organic, nutrient and suspended solids (SS) removals. The study found that media depth was important in contaminant removal in woodchip filters. Reductions of 78% chemical oxygen demand (COD), 95% SS, 85% total nitrogen (TN), 82% ammonium-nitrogen (NH4N), 50% total phosphorus (TP), and 54% dissolved reactive phosphorus (DRP) were measured in 1 m deep woodchip filters, which was greater than the reductions in 0.6 m deep woodchip filters. Woodchip filters also performed optimally when loaded at a high OLR (155 g COD m(-2) d(-1)), although the removal mechanism was primarily physical (i.e. straining) as opposed to biological. When operated at the same OLR and when of the same depth, the sand filters had better COD removals (96%) than woodchip (74%), but there was no significant difference between them in the removal of SS and NH4N. However, the likelihood of clogging makes sand filters less desirable than woodchip filters. Using the optimal designs of both configurations, the filter area required per cow for a woodchip filter is more than four times less than for a sand filter. Therefore, this study found that woodchip filters are more economically and environmentally effective in the treatment of DSW than sand filters, and optimal performance may be achieved using woodchip filters with a depth of at least 1 m, operated at an OLR of 155 g COD m(-2) d(-1). Copyright © 2016 Elsevier Ltd. All rights reserved.
Temporary Inferior Vena Cava Filters: How Do We Move Forward?
Arous, Edward J; Messina, Louis M
2016-05-01
Despite their widespread use, the indications for the selective use of temporary inferior vena cava (IVC) filters remains uncertain with few trials supporting their use. Additionally, the risks of long-term temporary IVC filter insertion are being increasingly discussed amongst the mainstream media and through multiple class action lawsuits. Retrievable IVC filters were specifically designed to have a less secure implantation in order to facilitate retrieval. However, multiple reports have demonstrated significant filter-related complications, most commonly related to duration of implantation. Furthermore, the risk is not isolated to one manufacturer alone. The incidence of filter-related complications is linearly related to its duration of time on the market. Currently, the FDA recommends that IVC filters be removed within 25-54 days of their implantation. Unfortunately, little evidence exists to show that this recommendation is followed routinely. Recently, the PRESERVE Trial (NCT02381509) was initiated as a multicenter non-randomized open label study to determine the safety and effectiveness of commercially available IVC filters (both temporary and permanent) in individuals who require mechanical prophylaxis against pulmonary embolism. Until such evidence is developed, temporary IVC filters should be implanted based on best available evidence and routinely removed within the guidelines of the FDA of 25-54 days. A fair question at this point is whether the design features themselves that are required to manufacture a low profile removable IVC filter can achieve effective prophylaxis against pulmonary embolism at a low rate of short and long-term complications. Copyright © 2016 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.
Shaper-Based Filters for the compensation of the load cell response in dynamic mass measurement
NASA Astrophysics Data System (ADS)
Richiedei, Dario; Trevisani, Alberto
2018-01-01
This paper proposes a novel model-based signal filtering technique for dynamic mass measurement through load cells. Load cells are sensors with an underdamped oscillatory response which usually imposes a long settling time. Real-time filtering is therefore necessary to compensate for such a dynamics and to quickly retrieve the mass of the measurand (which is the steady state value of the load cell response) before the measured signal actually settles. This problem has a big impact on the throughput of industrial weighing machines. In this paper a novel solution to this problem is developed: a model-based filtering technique is proposed to ensure accurate, robust and rapid estimation of the mass of the measurand. The digital filters proposed are referred to as Shaper-Based Filters (SBFs) and are based on the convolution of the load cell output signal with a sequence of few impulses (typically, between 2 and 5). The amplitudes and the instants of application of such impulses are computed through the analytical development of the load cell step response, by imposing the admissible residual oscillation in the steady-state filtered signal and by requiring the desired sensitivity of the filter. The inclusion of robustness specifications tackles effectively the unavoidable uncertainty and variability in the load cell frequency and damping. The effectiveness of the proposed filters is proved experimentally through an industrial set up: the load-cell-instrumented weigh bucket of a multihead weighing machine for packaging. A performance comparison with other benchmark filters is provided and discussed too.
Extracting tissue deformation using Gabor filter banks
NASA Astrophysics Data System (ADS)
Montillo, Albert; Metaxas, Dimitris; Axel, Leon
2004-04-01
This paper presents a new approach for accurate extraction of tissue deformation imaged with tagged MR. Our method, based on banks of Gabor filters, adjusts (1) the aspect and (2) orientation of the filter"s envelope and adjusts (3) the radial frequency and (4) angle of the filter"s sinusoidal grating to extract information about the deformation of tissue. The method accurately extracts tag line spacing, orientation, displacement and effective contrast. Existing, non-adaptive methods often fail to recover useful displacement information in the proximity of tissue boundaries while our method works in the proximity of the boundaries. We also present an interpolation method to recover all tag information at a finer resolution than the filter bank parameters. Results are shown on simulated images of translating and contracting tissue.
NASA Technical Reports Server (NTRS)
Stapleton, Thomas J. (Inventor)
2015-01-01
A concentric split flow filter may be configured to remove odor and/or bacteria from pumped air used to collect urine and fecal waste products. For instance, filter may be designed to effectively fill the volume that was previously considered wasted surrounding the transport tube of a waste management system. The concentric split flow filter may be configured to split the air flow, with substantially half of the air flow to be treated traveling through a first bed of filter media and substantially the other half of the air flow to be treated traveling through the second bed of filter media. This split flow design reduces the air velocity by 50%. In this way, the pressure drop of filter may be reduced by as much as a factor of 4 as compare to the conventional design.
Blind Source Parameters for Performance Evaluation of Despeckling Filters.
Biradar, Nagashettappa; Dewal, M L; Rohit, ManojKumar; Gowre, Sanjaykumar; Gundge, Yogesh
2016-01-01
The speckle noise is inherent to transthoracic echocardiographic images. A standard noise-free reference echocardiographic image does not exist. The evaluation of filters based on the traditional parameters such as peak signal-to-noise ratio, mean square error, and structural similarity index may not reflect the true filter performance on echocardiographic images. Therefore, the performance of despeckling can be evaluated using blind assessment metrics like the speckle suppression index, speckle suppression and mean preservation index (SMPI), and beta metric. The need for noise-free reference image is overcome using these three parameters. This paper presents a comprehensive analysis and evaluation of eleven types of despeckling filters for echocardiographic images in terms of blind and traditional performance parameters along with clinical validation. The noise is effectively suppressed using the logarithmic neighborhood shrinkage (NeighShrink) embedded with Stein's unbiased risk estimation (SURE). The SMPI is three times more effective compared to the wavelet based generalized likelihood estimation approach. The quantitative evaluation and clinical validation reveal that the filters such as the nonlocal mean, posterior sampling based Bayesian estimation, hybrid median, and probabilistic patch based filters are acceptable whereas median, anisotropic diffusion, fuzzy, and Ripplet nonlinear approximation filters have limited applications for echocardiographic images.
Hamamoto, Ryo; Ito, Hidemi; Hirohara, Makoto; Chang, Ryongsok; Hongo-Hirasaki, Tomoko; Hayashi, Tomohiro
2018-03-01
Membrane fouling commonly occurs in all filter types during virus filtration in protein-based biopharmaceutical manufacturing. Mechanisms of decline in virus filter performance due to membrane fouling were investigated using a cellulose-based virus filter as a model membrane. Filter performance was critically dependent on solution conditions; specifically, ionic strength. To understand the interaction between immunoglobulin G (IgG) and cellulose, sensors coated with cellulose were fabricated for surface plasmon resonance and quartz crystal microbalance with energy dissipation measurements. The primary cause of flux decline appeared to be irreversible IgG adsorption on the surface of the virus filter membrane. In particular, post-adsorption conformational changes in the IgG molecules promoted further irreversible IgG adsorption, a finding that could not be adequately explained by DLVO theory. Analyses of adsorption and desorption and conformational changes in IgG molecules on cellulose surfaces mimicking cellulose-based virus removal membranes provide an effective approach for identifying ways of optimizing solution conditions to maximize virus filter performance. © 2017 American Institute of Chemical Engineers Biotechnol. Prog., 34:379-386, 2018. © 2017 American Institute of Chemical Engineers.
Hall, G.E.M.; Bonham-Carter, G. F.; Horowitz, A.J.; Lum, K.; Lemieux, C.; Quemerais, B.; Garbarino, J.R.
1996-01-01
The effect of 4 different 0.45 ??m pore size filter membrane systems on the 'dissolved' concentration of 28 elements in 5 natural water samples of varying matrix is reported. In 3 of the 5 waters, consistently higher concentrations of most elements (minor and trace) are obtained using Nucleopore 47 mm filter and the cellulose acetate/nitrate 47 mm filter than those measured using the 142 mm cellulose nitrate MFS filter or the Gelman capsule 47 mm filter. These distinct and coherent patterns in elemental behaviour disappear for the other 2 samples, an organic-rich peat water of high suspended load and a mineralised sample high in Si and Ca. Thus the nature and degree of filtration artifacts is matrix-dependent. These trends are evident in both data sets produced by 2 independent laboratories using different instrumentation, techniques and calibrating procedures. The average relative standard deviation in elemental concentration across the 4 filter types is in the range 9-21%. The presence of such filtration artifacts must be considered in projects where, for example, seasonal variability of water composition is under examination, data from various sources are being merged or hydrogeochemical surveys are being conducted.
Sánchez Rodríguez, A; Rodrigo Sanz, M; Betancort Rodríguez, J R
2015-07-01
Due to the growing concern about human health effects of ultraviolet (UV) radiation, the use of UV filters has increased in recent decades. Unfortunately, some common UV filters are bioaccumulated in aquatic organisms and show a potential for estrogenic activity. The aim of the present study is to determine the presence of some UV filters in the coastal waters of six beaches around Gran Canaria Island as consequence of recreational seaside activities. Eight commonly used UV filters: benzophenone-3 (BP-3), octocrylene (OC), octyl-dimethyl-PABA (OD-PABA), ethylhexyl methoxy cinnamate (EHMC), homosalate (HMS), butyl methoxydibenzoyl methane (BMDBM), 4-methylbenzylidene camphor (4-MBC) and diethylamino hydroxybenzoyl hexyl benzoate (DHHB), were monitored and, with the exception of OD-PABA, all were detected in the samples collected. 99% of the samples showed some UV filters and concentration levels reached up to 3316.7 ng/L for BP-3. Environmental risk assessment (ERA) approach showed risk quotients (RQ) higher than 10, which means that there is a significant potential for adverse effects, for 4-MBC and EHMC for those samples with highest levels of UV filters. Copyright © 2015 Elsevier Ltd. All rights reserved.
Collisional considerations in axial-collection plasma mass filters
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ochs, I. E.; Gueroult, R.; Fisch, N. J.
The chemical inhomogeneity of nuclear waste makes chemical separations difficult, while the correlation between radioactivity and nuclear mass makes mass-based separation, and in particular plasma-based separation, an attractive alternative. Here, we examine a particular class of plasma mass filters, namely filters in which (a) species of different masses are collected along magnetic field lines at opposite ends of an open-field-line plasma device and (b) gyro-drift effects are important for the separation process. Using an idealized cylindrical model, we derive a set of dimensionless parameters which provide minimum necessary conditions for an effective mass filter function in the presence of ion-ionmore » and ion-neutral collisions. Through simulations of the constant-density profile, turbulence-free devices, we find that these parameters accurately describe the mass filter performance in more general magnetic geometries. We then use these parameters to study the design and upgrade of current experiments, as well as to derive general scalings for the throughput of production mass filters. Most importantly, we find that ion temperatures above 3 eV and magnetic fields above 104 G are critical to ensure a feasible mass filter function when operating at an ion density of 10 13 cm –3.« less
Collisional considerations in axial-collection plasma mass filters
Ochs, I. E.; Gueroult, R.; Fisch, N. J.; ...
2017-04-01
The chemical inhomogeneity of nuclear waste makes chemical separations difficult, while the correlation between radioactivity and nuclear mass makes mass-based separation, and in particular plasma-based separation, an attractive alternative. Here, we examine a particular class of plasma mass filters, namely filters in which (a) species of different masses are collected along magnetic field lines at opposite ends of an open-field-line plasma device and (b) gyro-drift effects are important for the separation process. Using an idealized cylindrical model, we derive a set of dimensionless parameters which provide minimum necessary conditions for an effective mass filter function in the presence of ion-ionmore » and ion-neutral collisions. Through simulations of the constant-density profile, turbulence-free devices, we find that these parameters accurately describe the mass filter performance in more general magnetic geometries. We then use these parameters to study the design and upgrade of current experiments, as well as to derive general scalings for the throughput of production mass filters. Most importantly, we find that ion temperatures above 3 eV and magnetic fields above 104 G are critical to ensure a feasible mass filter function when operating at an ion density of 10 13 cm –3.« less
Blind Source Parameters for Performance Evaluation of Despeckling Filters
Biradar, Nagashettappa; Dewal, M. L.; Rohit, ManojKumar; Gowre, Sanjaykumar; Gundge, Yogesh
2016-01-01
The speckle noise is inherent to transthoracic echocardiographic images. A standard noise-free reference echocardiographic image does not exist. The evaluation of filters based on the traditional parameters such as peak signal-to-noise ratio, mean square error, and structural similarity index may not reflect the true filter performance on echocardiographic images. Therefore, the performance of despeckling can be evaluated using blind assessment metrics like the speckle suppression index, speckle suppression and mean preservation index (SMPI), and beta metric. The need for noise-free reference image is overcome using these three parameters. This paper presents a comprehensive analysis and evaluation of eleven types of despeckling filters for echocardiographic images in terms of blind and traditional performance parameters along with clinical validation. The noise is effectively suppressed using the logarithmic neighborhood shrinkage (NeighShrink) embedded with Stein's unbiased risk estimation (SURE). The SMPI is three times more effective compared to the wavelet based generalized likelihood estimation approach. The quantitative evaluation and clinical validation reveal that the filters such as the nonlocal mean, posterior sampling based Bayesian estimation, hybrid median, and probabilistic patch based filters are acceptable whereas median, anisotropic diffusion, fuzzy, and Ripplet nonlinear approximation filters have limited applications for echocardiographic images. PMID:27298618
Consequences of broad auditory filters for identification of multichannel-compressed vowels
Souza, Pamela; Wright, Richard; Bor, Stephanie
2012-01-01
Purpose In view of previous findings (Bor, Souza & Wright, 2008) that some listeners are more susceptible to spectral changes from multichannel compression (MCC) than others, this study addressed the extent to which differences in effects of MCC were related to differences in auditory filter width. Method Listeners were recruited in three groups: listeners with flat sensorineural loss, listeners with sloping sensorineural loss, and a control group of listeners with normal hearing. Individual auditory filter measurements were obtained at 500 and 2000 Hz. The filter widths were related to identification of vowels processed with 16-channel MCC and with a control (linear) condition. Results Listeners with flat loss had broader filters at 500 Hz but not at 2000 Hz, compared to listeners with sloping loss. Vowel identification was poorer for MCC compared to linear amplification. Listeners with flat loss made more errors than listeners with sloping loss, and there was a significant relationship between filter width and the effects of MCC. Conclusions Broadened auditory filters can reduce the ability to process amplitude-compressed vowel spectra. This suggests that individual frequency selectivity is one factor which influences benefit of MCC, when a high number of compression channels are used. PMID:22207696
Brown, Joe; Sobsey, Mark D
2010-03-01
Low-cost options for the treatment of drinking water at the household level are being explored by the Cambodian government and non-governmental organizations (NGOs) working in Cambodia, where many lack access to improved drinking water sources and diarrhoeal diseases are the most prevalent cause of death in children under 5 years of age. The ceramic water purifier (CWP), a locally produced, low-cost ceramic filter, is now being implemented by several NGOs, and an estimated 100,000+households in the country now use them for drinking water treatment. Two candidate filters were tested for the reduction of bacterial and viral surrogates for waterborne pathogens using representative Cambodian drinking water sources (rainwater and surface water) spiked with Escherichia coli and bacteriophage MS2. Results indicate that filters were capable of reducing key microbes in the laboratory with mean reductions of E. coli of approximately 99% and mean reduction of bacteriophages of 90-99% over >600 litres throughput. Increased effectiveness was not observed in filters with an AgNO3 amendment. At under US$10 per filter, locally produced ceramic filters may be a promising option for drinking water treatment and safe storage at the household level.
Wet particle source identification and reduction using a new filter cleaning process
NASA Astrophysics Data System (ADS)
Umeda, Toru; Morita, Akihiko; Shimizu, Hideki; Tsuzuki, Shuichi
2014-03-01
Wet particle reduction during filter installation and start-up aligns closely with initiatives to reduce both chemical consumption and preventative maintenance time. The present study focuses on the effects of filter materials cleanliness on wet particle defectivity through evaluation of filters that have been treated with a new enhanced cleaning process focused on organic compounds reduction. Little difference in filter performance is observed between the two filter types at a size detection threshold of 60 nm, while clear differences are observed at that of 26 nm. It can be suggested that organic compounds can be identified as a potential source of wet particles. Pall recommends filters that have been treated with the special cleaning process for applications with a critical defect size of less than 60 nm. Standard filter products are capable to satisfy wet particle defect performance criteria in less critical lithography applications.
Kalman and particle filtering methods for full vehicle and tyre identification
NASA Astrophysics Data System (ADS)
Bogdanski, Karol; Best, Matthew C.
2018-05-01
This paper considers identification of all significant vehicle handling dynamics of a test vehicle, including identification of a combined-slip tyre model, using only those sensors currently available on most vehicle controller area network buses. Using an appropriately simple but efficient model structure, all of the independent parameters are found from test vehicle data, with the resulting model accuracy demonstrated on independent validation data. The paper extends previous work on augmented Kalman Filter state estimators to concentrate wholly on parameter identification. It also serves as a review of three alternative filtering methods; identifying forms of the unscented Kalman filter, extended Kalman filter and particle filter are proposed and compared for effectiveness, complexity and computational efficiency. All three filters are suited to applications of system identification and the Kalman Filters can also operate in real-time in on-line model predictive controllers or estimators.
A superior edge preserving filter with a systematic analysis
NASA Technical Reports Server (NTRS)
Holladay, Kenneth W.; Rickman, Doug
1991-01-01
A new, adaptive, edge preserving filter for use in image processing is presented. It had superior performance when compared to other filters. Termed the contiguous K-average, it aggregates pixels by examining all pixels contiguous to an existing cluster and adding the pixel closest to the mean of the existing cluster. The process is iterated until K pixels were accumulated. Rather than simply compare the visual results of processing with this operator to other filters, some approaches were developed which allow quantitative evaluation of how well and filter performs. Particular attention is given to the standard deviation of noise within a feature and the stability of imagery under iterative processing. Demonstrations illustrate the performance of several filters to discriminate against noise and retain edges, the effect of filtering as a preprocessing step, and the utility of the contiguous K-average filter when used with remote sensing data.
NASA Astrophysics Data System (ADS)
Wang, Fan; Liang, Jinling; Dobaie, Abdullah M.
2018-07-01
The resilient filtering problem is considered for a class of time-varying networks with stochastic coupling strengths. An event-triggered strategy is adopted to save the network resources by scheduling the signal transmission from the sensors to the filters based on certain prescribed rules. Moreover, the filter parameters to be designed are subject to gain perturbations. The primary aim of the addressed problem is to determine a resilient filter that ensures an acceptable filtering performance for the considered network with event-triggering scheduling. To handle such an issue, an upper bound on the estimation error variance is established for each node according to the stochastic analysis. Subsequently, the resilient filter is designed by locally minimizing the derived upper bound at each iteration. Moreover, rigorous analysis shows the monotonicity of the minimal upper bound regarding the triggering threshold. Finally, a simulation example is presented to show effectiveness of the established filter scheme.
MANUFACTURING FACILITY FOR ACTIVATED CARBON AND CERAMIC WATER FILTERS AT THE SONGHAI CENTER, BENIN
Ceramic filters will be manufactured at the Songhai Center in Porto-Novo, Benin for cost-effective drinking water treatment. The efficiency of the ceramic filters will be improved by adding activated carbon cartridges to remove organic and inorganic impurities. The activate...
USDA-ARS?s Scientific Manuscript database
Grass filter strips are a widely used conservation practice in the Midwestern United States for reducing nutrient, pesticide, and sediment inputs into agricultural streams. Only a limited amount of information is available on the ecological effects of planting grass filter strips adjacent to channe...
The detection of enteric viruses in environmental water usually requires the concentration of viruses from large volumes of water. The 1MDS electropositive filter is commonly used for concentrating enteric viruses from water but unfortunately these filters are not cost-effective...
Theoretical model for a Faraday anomalous dispersion optical filter
NASA Technical Reports Server (NTRS)
Yin, B.; Shay, T. M.
1991-01-01
A model for the Faraday anomalous dispersion optical filter is presented. The model predicts a bandwidth of 0.6 GHz and a transmission peak of 0.98 for a filter operating on the Cs (D2) line. The model includes hyperfine effects and is valid for arbitrary magnetic fields.
Preprocessing of PHERMEX flash radiographic images with Haar and adaptive filtering
DOE Office of Scientific and Technical Information (OSTI.GOV)
Brolley, J.E.
1978-11-01
Work on image preparation has continued with the application of high-sequency boosting via Haar filtering. This is useful in developing line or edge structures. Widrow LMS adaptive filtering has also been shown to be useful in developing edge structure in special problems. Shadow effects can be obtained with the latter which may be useful for some problems. Combined Haar and adaptive filtering is illustrated for a PHERMEX image.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Jacks, Robert; Stormo, Julie; Rose, Coralie
Data have demonstrated that filter media lose tensile strength and the ability to resist the effects of moisture as a function of age. Testing of new and aged filters needs to be conducted to correlate reduction of physical strength of HEPA media to the ability of filters to withstand upset conditions. Appendix C of the Nuclear Air Cleaning Handbook provides the basis for DOE’s HEPA filter service life guidance. However, this appendix also points out the variability of data, and it does not correlate performance of aged filters to degradation of media due to age. Funding awarded by NSR&D tomore » initiate full-scale testing of aged HEPA filters addresses the issue of correlating media degradation due to age with testing of new and aged HEPA filters under a generic design basis event set of conditions. This funding has accelerated the process of describing this study via: (1) establishment of a Technical Working Group of all stakeholders, (2) development and approval of a test plan, (3) development of testing and autopsy procedures, (4) acquiring an initial set of aged filters, (5) testing the initial set of aged filters, and (6) developing the filter test report content for each filter tested. This funding was very timely and has moved the project forward by at least three years. Activities have been correlated with testing conducted under DOE-EM funding for evaluating performance envelopes for AG-1 Section FC Separator and Separatorless filters. This coordination allows correlation of results from the NSR&D Aged Filter Study with results from testing new filters of the Separator and Separatorless Filter Study. DOE-EM efforts have identified approximately 100 more filters of various ages that have been stored under Level B conditions. NSR&D funded work allows a time for rigorous review among subject matter experts before moving forward with development of the testing matrix that will be used for additional filters. The NSR&D data sets are extremely valuable in as much as establishing a selfimproving, NQA-1 program capable of advancing the service lifetime study of HEPA filters. The data and reports are available for careful and critical review by subject matter experts before the next set of filters is tested and can be found in the appendices of this final report. NSR&D funds have not only initiated the Aged HEPA Filter Study alluded to in Appendix C of the NACH, but have also enhanced the technical integrity and effectiveness of all of the follow-on testing for this long-term study.« less
NASA Technical Reports Server (NTRS)
Takacs, Lawrence L.; Sawyer, William; Suarez, Max J. (Editor); Fox-Rabinowitz, Michael S.
1999-01-01
This report documents the techniques used to filter quantities on a stretched grid general circulation model. Standard high-latitude filtering techniques (e.g., using an FFT (Fast Fourier Transformations) to decompose and filter unstable harmonics at selected latitudes) applied on a stretched grid are shown to produce significant distortions of the prognostic state when used to control instabilities near the pole. A new filtering technique is developed which accurately accounts for the non-uniform grid by computing the eigenvectors and eigenfrequencies associated with the stretching. A filter function, constructed to selectively damp those modes whose associated eigenfrequencies exceed some critical value, is used to construct a set of grid-spaced weights which are shown to effectively filter without distortion. Both offline and GCM (General Circulation Model) experiments are shown using the new filtering technique. Finally, a brief examination is also made on the impact of applying the Shapiro filter on the stretched grid.
Real-Time Wavelength Discrimination for Improved Neutron Discrimination in CLYC
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hornback, Donald Eric; Hu, Michael Z.; Bell, Zane W.
We investigated the effects of optical filters on the pulse shape discrimination properties of Cs 2LiYCl 6:Ce (CLYC) scintillator crystals. By viewing the scintillation light through various optical filters, we attempted to better distinguish between neutron and gamma ray events in the crystal. We applied commercial interference and colored glass filters in addition to fabricating quantum dot (QD) filters by suspending QDs in plastic films and glass. QD filters ultimately failed because of instability of the QDs with respect to oxidation when exposed to ambient air, and the tendency of the QDs to aggregate in the plastic. Of the commercialmore » filters, the best results were obtained with a bandpass interference filter covering the spectral region containing core-valence luminescence (CVL) light. However, the PSD response of filtered CLYC light was always poorer than the response exhibited by unfiltered light because filters always reduced the amount of light available for signal processing.« less
NASA Astrophysics Data System (ADS)
Jia, Xiaodong; Zhao, Ming; Di, Yuan; Jin, Chao; Lee, Jay
2017-01-01
Minimum Entropy Deconvolution (MED) filter, which is a non-parametric approach for impulsive signature detection, has been widely studied recently. Although the merits of the MED filter are manifold, this method tends to over highlight the dominant peaks and its performance becomes less stable when strong noise exists. In order to better understand the behavior of the MED filter, this study first investigated the mathematical fundamentals of the MED filter and then explained the reason why the MED filter tends to over highlight the dominant peaks. In order to pursue finer solutions for weak impulsive signature enhancement, the Convolutional Sparse Filter (CSF) is originally proposed in this work and the derivation of the CSF is presented in details. The superiority of the proposed CSF over the MED filter is validated by both simulated data and experimental data. The results demonstrate that CSF is an effective method for impulsive signature enhancement that could be applied in rotating machines for incipient fault detection.
Uncertainties in the measurements of water-soluble organic nitrogen in the aerosol
NASA Astrophysics Data System (ADS)
Matsumoto, Kiyoshi; Yamato, Koki
2016-11-01
In order to evaluate the positive and negative artifacts in the measurements of the water-soluble organic nitrogen (WSON) in the aerosols by filter sampling, comparative experiments between the filter sampling and denuder-filter sampling were conducted during both the warm and cold seasons. The results suggest that the traditional filter sampling underestimates the concentrations of the particulate WSON due to its volatilization loss, but this effect on the ratio of the WSON to the water-soluble total nitrogen (WSTN) was small probably because inorganic nitrogen species were also lost during the filter sampling. Approximately 32.5% of the WSON in the PM2.5 was estimated to be lost during the filter sampling. The denuder-filter sampling also demonstrated the existence of the WSON in the gas phase with approximately quarter concentrations of the WSON in the PM2.5. On the other hand, the filter sampling would overestimate the gaseous WSON concentration due to the loss of the WSON from the aerosol collection filter.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Poirier, M. R.; Burket, P. R.; Duignan, M. R.
2015-03-12
The Savannah River Site (SRS) is currently treating radioactive liquid waste with the Actinide Removal Process (ARP) and the Modular Caustic Side Solvent Extraction Unit (MCU). The low filter flux through the ARP has limited the rate at which radioactive liquid waste can be treated. Recent filter flux has averaged approximately 5 gallons per minute (gpm). Salt Batch 6 has had a lower processing rate and required frequent filter cleaning. Savannah River Remediation (SRR) has a desire to understand the causes of the low filter flux and to increase ARP/MCU throughput. In addition, at the time the testing started, SRRmore » was assessing the impact of replacing the 0.1 micron filter with a 0.5 micron filter. This report describes testing of MST filterability to investigate the impact of filter pore size and MST particle size on filter flux and testing of filter enhancers to attempt to increase filter flux. The authors constructed a laboratory-scale crossflow filter apparatus with two crossflow filters operating in parallel. One filter was a 0.1 micron Mott sintered SS filter and the other was a 0.5 micron Mott sintered SS filter. The authors also constructed a dead-end filtration apparatus to conduct screening tests with potential filter aids and body feeds, referred to as filter enhancers. The original baseline for ARP was 5.6 M sodium salt solution with a free hydroxide concentration of approximately 1.7 M.3 ARP has been operating with a sodium concentration of approximately 6.4 M and a free hydroxide concentration of approximately 2.5 M. SRNL conducted tests varying the concentration of sodium and free hydroxide to determine whether those changes had a significant effect on filter flux. The feed slurries for the MST filterability tests were composed of simple salts (NaOH, NaNO 2, and NaNO 3) and MST (0.2 – 4.8 g/L). The feed slurry for the filter enhancer tests contained simulated salt batch 6 supernate, MST, and filter enhancers.« less
Ozáez, Irene; Morcillo, Gloria; Martínez-Guitarte, José-Luis
2016-07-01
Several organic UV filters have hormonal activity in vertebrates, as demonstrated in fishes, rodents and human cells. Despite the accumulation of filter contaminants in aquatic systems, research on their effects on the endocrine systems of freshwaters invertebrates is scarce. In this work, the effects of five frequently used UV filters were investigated in embryos and larvae of Chironomus riparius, which is a reference organism in ecotoxicology. LC50 values for larvae as well as the percentage of eclosion of eggs were determined following exposures to: octyl-p-methoxycinnamate (OMC) also known as 2-ethylhexyl-4-methoxycinnamate (EHMC); 4-methylbenzylidene camphor (4MBC); 4-hydroxybenzophenone (4HB); octocrylene (OC); and octyldimethyl-p-aminobenzoate (OD-PABA). To assess sublethal effects, expression levels of the genes coding for the ecdysone receptor (EcR) and heat shock protein HSP70 were investigated as biomarkers for endocrine and stress effects at the cellular level. Life-stage-dependent sensitivity was found. In embryos, all of the UV filters provoked a significant overexpression of EcR at 24h after exposure. OC, 4MBC and OD-PABA also triggered transcriptional activation of the hsp70 stress gene in embryos. In contrast, in larvae, only 4MBC and OMC/EHMC increased EcR and hsp70 mRNA levels and OD-PABA upregulated only the EcR gene. These results revealed that embryos are particularly sensitive to UV filters, which affect endocrine regulation during development. Most UV filters also triggered the cellular stress response, and thus exhibit proteotoxic effects. The differences observed between embryos and larvae and the higher sensitivity of embryos highlight the importance of considering different life stages when evaluating the environmental risks of pollutants, particularly when analyzing endocrine effects. Copyright © 2016 Elsevier B.V. All rights reserved.
A comparison of the static and flow methods for the detection of ice nuclei
NASA Astrophysics Data System (ADS)
Hussain, K.; Kayani, S. A.
The use of the membrane-filter processing chamber to study ice nuclei concentrations has become wide-spread since its introduction by Bigg et al. in 1961. The technique is convenient because of the simplicity of its operation and because it could be run remote from the place of field study. It has however been found to suffer from a number of drawbacks, namely, the volume effect, the chamber height effect, the vapour depletion effect, etc. Comparison of the results obtained by running a traditional filter processor and a continuous flow chamber under identical temperature and humidity conditions for polluted Manchester air has shown that the latter technique detects more ice nuclei than the former one by a factor of about 14±4. These results confirm that the filter technique suffers from the vapour depletion effect. The present results are in agreement with Bigg et al., Mossop and Thorndike, and King. In the light of our findings the filter technique does not appear to be a standard method. Therefore the ice nuclei data obtained with the filter method should not be extended to clouds in order to study their microphysical properties.
Byers, Stephanie; Vinyard, Gary L
1990-06-01
A series of mesocosm experiments was performed to assess the effects on the plankton community of filter-feeding Sacramento blackfish (Cyprinidae; Orthodon microlepidotus). Phytoplankton size-frequency distribution, zooplankton abundance, primary production, potential secondary production, and nutrient concentrations were measured. Blackfish reduce numbers of both evasive and nonevasive zooplankton and large phytoplankton while enhancing nanoplankton densities. Blackfish also significantly increase primary production and potential secondary community production. Levels of dissolved inorganic phosphorus and ammonia-nitrogen also increase. The effects of blackfish are generally similar to those reported for other filter-feeding fish.
Conditions for successful data assimilation
NASA Astrophysics Data System (ADS)
Morzfeld, M.; Chorin, A. J.
2013-12-01
Many applications in science and engineering require that the predictions of uncertain models be updated by information from a stream of noisy data. The model and the data jointly define a conditional probability density function (pdf), which contains all the information one has about the process of interest and various numerical methods can be used to study and approximate this pdf, e.g. the Kalman filter, variational methods or particle filters. Given a model and data, each of these algorithms will produce a result. We are interested in the conditions under which this result is reasonable, i.e. consistent with the real-life situation one is modeling. In particular, we show, using idealized models, that numerical data assimilation is feasible in principle only if a suitably defined effective dimension of the problem is not excessive. This effective dimension depends on the noise in the model and the data, and in physically reasonable problems it can be moderate even when the number of variables is huge. In particular, we find that the effective dimension being moderate induces a balance condition between the noises in the model and the data; this balance condition is often satisfied in realistic applications or else the noise levels are excessive and drown the underlying signal. We also study the effects of the effective dimension on particle filters in two instances, one in which the importance function is based on the model alone, and one in which it is based on both the model and the data. We have three main conclusions: (1) the stability (i.e., non-collapse of weights) in particle filtering depends on the effective dimension of the problem. Particle filters can work well if the effective dimension is moderate even if the true dimension is large (which we expect to happen often in practice). (2) A suitable choice of importance function is essential, or else particle filtering fails even when data assimilation is feasible in principle with a sequential algorithm. (3) There is a parameter range in which the model noise and the observation noise are roughly comparable, and in which even the optimal particle filter collapses, even under ideal circumstances. We further study the role of the effective dimension in variational data assimilation and particle smoothing, for both the weak and strong constraint problem. It was found that these methods too require a moderate effective dimension or else no accurate predictions can be expected. Moreover, variational data assimilation or particle smoothing may be applicable in the parameter range where particle filtering fails, because the use of more than one consecutive data set helps reduce the variance which is responsible for the collapse of the filters.
Lyu, Weiwei; Cheng, Xianghong
2017-11-28
Transfer alignment is always a key technology in a strapdown inertial navigation system (SINS) because of its rapidity and accuracy. In this paper a transfer alignment model is established, which contains the SINS error model and the measurement model. The time delay in the process of transfer alignment is analyzed, and an H∞ filtering method with delay compensation is presented. Then the H∞ filtering theory and the robust mechanism of H∞ filter are deduced and analyzed in detail. In order to improve the transfer alignment accuracy in SINS with time delay, an adaptive H∞ filtering method with delay compensation is proposed. Since the robustness factor plays an important role in the filtering process and has effect on the filtering accuracy, the adaptive H∞ filter with delay compensation can adjust the value of robustness factor adaptively according to the dynamic external environment. The vehicle transfer alignment experiment indicates that by using the adaptive H∞ filtering method with delay compensation, the transfer alignment accuracy and the pure inertial navigation accuracy can be dramatically improved, which demonstrates the superiority of the proposed filtering method.
Zhang, Tao; Zhu, Yongyun; Zhou, Feng; Yan, Yaxiong; Tong, Jinwu
2017-06-17
Initial alignment of the strapdown inertial navigation system (SINS) is intended to determine the initial attitude matrix in a short time with certain accuracy. The alignment accuracy of the quaternion filter algorithm is remarkable, but the convergence rate is slow. To solve this problem, this paper proposes an improved quaternion filter algorithm for faster initial alignment based on the error model of the quaternion filter algorithm. The improved quaternion filter algorithm constructs the K matrix based on the principle of optimal quaternion algorithm, and rebuilds the measurement model by containing acceleration and velocity errors to make the convergence rate faster. A doppler velocity log (DVL) provides the reference velocity for the improved quaternion filter alignment algorithm. In order to demonstrate the performance of the improved quaternion filter algorithm in the field, a turntable experiment and a vehicle test are carried out. The results of the experiments show that the convergence rate of the proposed improved quaternion filter is faster than that of the tradition quaternion filter algorithm. In addition, the improved quaternion filter algorithm also demonstrates advantages in terms of correctness, effectiveness, and practicability.
A periodic spatio-spectral filter for event-related potentials.
Ghaderi, Foad; Kim, Su Kyoung; Kirchner, Elsa Andrea
2016-12-01
With respect to single trial detection of event-related potentials (ERPs), spatial and spectral filters are two of the most commonly used pre-processing techniques for signal enhancement. Spatial filters reduce the dimensionality of the data while suppressing the noise contribution and spectral filters attenuate frequency components that most likely belong to noise subspace. However, the frequency spectrum of ERPs overlap with that of the ongoing electroencephalogram (EEG) and different types of artifacts. Therefore, proper selection of the spectral filter cutoffs is not a trivial task. In this research work, we developed a supervised method to estimate the spatial and finite impulse response (FIR) spectral filters, simultaneously. We evaluated the performance of the method on offline single trial classification of ERPs in datasets recorded during an oddball paradigm. The proposed spatio-spectral filter improved the overall single-trial classification performance by almost 9% on average compared with the case that no spatial filters were used. We also analyzed the effects of different spectral filter lengths and the number of retained channels after spatial filtering. Copyright © 2016. Published by Elsevier Ltd.
Methodology for modeling the microbial contamination of air filters.
Joe, Yun Haeng; Yoon, Ki Young; Hwang, Jungho
2014-01-01
In this paper, we propose a theoretical model to simulate microbial growth on contaminated air filters and entrainment of bioaerosols from the filters to an indoor environment. Air filter filtration and antimicrobial efficiencies, and effects of dust particles on these efficiencies, were evaluated. The number of bioaerosols downstream of the filter could be characterized according to three phases: initial, transitional, and stationary. In the initial phase, the number was determined by filtration efficiency, the concentration of dust particles entering the filter, and the flow rate. During the transitional phase, the number of bioaerosols gradually increased up to the stationary phase, at which point no further increase was observed. The antimicrobial efficiency and flow rate were the dominant parameters affecting the number of bioaerosols downstream of the filter in the transitional and stationary phase, respectively. It was found that the nutrient fraction of dust particles entering the filter caused a significant change in the number of bioaerosols in both the transitional and stationary phases. The proposed model would be a solution for predicting the air filter life cycle in terms of microbiological activity by simulating the microbial contamination of the filter.
Nonlinear estimation theory applied to orbit determination
NASA Technical Reports Server (NTRS)
Choe, C. Y.
1972-01-01
The development of an approximate nonlinear filter using the Martingale theory and appropriate smoothing properties is considered. Both the first order and the second order moments were estimated. The filter developed can be classified as a modified Gaussian second order filter. Its performance was evaluated in a simulated study of the problem of estimating the state of an interplanetary space vehicle during both a simulated Jupiter flyby and a simulated Jupiter orbiter mission. In addition to the modified Gaussian second order filter, the modified truncated second order filter was also evaluated in the simulated study. Results obtained with each of these filters were compared with numerical results obtained with the extended Kalman filter and the performance of each filter is determined by comparison with the actual estimation errors. The simulations were designed to determine the effects of the second order terms in the dynamic state relations, the observation state relations, and the Kalman gain compensation term. It is shown that the Kalman gain-compensated filter which includes only the Kalman gain compensation term is superior to all of the other filters.
Neural control of enhanced filtering demands in a combined Flanker and Garner conflict task.
Berron, David; Frühholz, Sascha; Herrmann, Manfred
2015-01-01
Several studies demonstrated that visual filtering mechanisms might underlie both conflict resolution of the Flanker conflict and the control of the Garner effect. However, it remains unclear whether the mechanisms involved in the processing of both effects depend on similar filter mechanisms, such that especially the Garner effect is able to modulate filtering needs in the Flanker conflict. In the present experiment twenty-four subjects participated in a combined Garner and Flanker task during two runs of functional magnetic resonance imaging (fMRI) recordings. Behavioral data showed a significant Flanker but no Garner effect. A run-wise analysis, however, revealed a Flanker effect in the Garner filtering condition in the first experimental run, while we found a Flanker effect in the Garner baseline condition in the second experimental run. The fMRI data revealed a fronto-parietal network involved in the processing of both types of effects. Flanker interference was associated with activity in the inferior frontal gyrus, the anterior cingulate cortex, the precuneus as well as the inferior (IPL) and superior parietal lobule (SPL). Garner interference was associated with activation in middle frontal and middle temporal gyrus, the lingual gyrus as well as the IPL and SPL. Interaction analyses between the Garner and the Flanker effect additionally revealed differences between the two experimental runs. In the first experimental run, activity specifically related to the interaction of effects was found in frontal and parietal regions, while in the second run we found activity in the hippocampus, the parahippocampal cortex and the basal ganglia. This shift in activity for the interaction effects might be associated with a task-related learning process to control filtering demands. Especially perceptual learning mechanisms might play a crucial role in the present Flanker and Garner task design and, therefore, increased performance in the second experimental run could be the reason for the lack of behavioral Garner interference on the level of the whole experiment.
Switching non-local median filter
NASA Astrophysics Data System (ADS)
Matsuoka, Jyohei; Koga, Takanori; Suetake, Noriaki; Uchino, Eiji
2015-06-01
This paper describes a novel image filtering method for removal of random-valued impulse noise superimposed on grayscale images. Generally, it is well known that switching-type median filters are effective for impulse noise removal. In this paper, we propose a more sophisticated switching-type impulse noise removal method in terms of detail-preserving performance. Specifically, the noise detector of the proposed method finds out noise-corrupted pixels by focusing attention on the difference between the value of a pixel of interest (POI) and the median of its neighboring pixel values, and on the POI's isolation tendency from the surrounding pixels. Furthermore, the removal of the detected noise is performed by the newly proposed median filter based on non-local processing, which has superior detail-preservation capability compared to the conventional median filter. The effectiveness and the validity of the proposed method are verified by some experiments using natural grayscale images.
Filter and Grid Resolution in DG-LES
NASA Astrophysics Data System (ADS)
Miao, Ling; Sammak, Shervin; Madnia, Cyrus K.; Givi, Peyman
2017-11-01
The discontinuous Galerkin (DG) methodology has proven very effective for large eddy simulation (LES) of turbulent flows. Two important parameters in DG-LES are the grid resolution (h) and the filter size (Δ). In most previous work, the filter size is usually set to be proportional to the grid spacing. In this work, the DG method is combined with a subgrid scale (SGS) closure which is equivalent to that of the filtered density function (FDF). The resulting hybrid scheme is particularly attractive because a larger portion of the resolved energy is captured as the order of spectral approximation increases. Different cases for LES of a three-dimensional temporally developing mixing layer are appraised and a systematic parametric study is conducted to investigate the effects of grid resolution, the filter width size, and the order of spectral discretization. Comparative assessments are also made via the use of high resolution direct numerical simulation (DNS) data.
Removal of ozone on clean, dusty and sooty supply air filters
NASA Astrophysics Data System (ADS)
Hyttinen, Marko; Pasanen, Pertti; Kalliokoski, Pentti
The removal of ozone (O 3) on supply air filters was studied. Especially, the effects of dust load, diesel soot, relative humidity (RH), and exposure time on the removal of O 3 were investigated. Some loss of O 3 was observed in all the filters, except in an unused G3 pre-filter made of polyester. Dust load and quality influenced the reduction of O 3; especially, diesel soot removed O 3 effectively. Increasing the RH resulted in a larger O 3 removal. The removal of O 3 was highest in the beginning of the test, but it declined within 2 h reaching almost a steady state as the exposure continued. However, the sooty filters continued to remove as much as 25-30% of O 3. Up to 11% of O 3 removed participated in the production of formaldehyde. Small amounts of other oxidation products were also detected.
Temporal processing and adaptation in the songbird auditory forebrain.
Nagel, Katherine I; Doupe, Allison J
2006-09-21
Songbird auditory neurons must encode the dynamics of natural sounds at many volumes. We investigated how neural coding depends on the distribution of stimulus intensities. Using reverse-correlation, we modeled responses to amplitude-modulated sounds as the output of a linear filter and a nonlinear gain function, then asked how filters and nonlinearities depend on the stimulus mean and variance. Filter shape depended strongly on mean amplitude (volume): at low mean, most neurons integrated sound over many milliseconds, while at high mean, neurons responded more to local changes in amplitude. Increasing the variance (contrast) of amplitude modulations had less effect on filter shape but decreased the gain of firing in most cells. Both filter and gain changes occurred rapidly after a change in statistics, suggesting that they represent nonlinearities in processing. These changes may permit neurons to signal effectively over a wider dynamic range and are reminiscent of findings in other sensory systems.
NASA Technical Reports Server (NTRS)
Seeley, J. S.; Hunneman, R.; Whatley, A.; Lipscombe, D. R.
1984-01-01
Infrared multilayer interface filter which were used in satellite radiometers were examined. The ability of the filters to withstand the space environment in these applications is critical. An experiment on the LDEF subjects the filters to authoritative spectral measurements following space exposure to ascertain their suitability for spacecraft use and to permit an understanding of degradation mechanisms. The understanding of the effects of prolonged space exposure on spacecraft materials, surface finishes, and adhesive systems is important to the spacecraft designer. Materials technology experiments and experiment on infrared multilayer filters are discussed.
Kotb, Hussein; Abdelalim, Mohamed A; Anis, Hanan
2015-11-16
A significant change in active similariton characteristics, both numerically and experimentally, is observed as a function of the location of the lumped spectral filter. The closer the spectral filter is to the input of the Yb(3+)-doped fiber, the shorter the de-chirped pulse width. The peak power of the de-chirped pulse has its maximum value at a certain location of the spectral filter. Four different positions of the spectral filter inside the laser cavity have been theoretically studied and two of them have been verified experimentally.
Ammonia-nitrogen and Phosphate Reduction by Bio-Filter using Factorial Design
NASA Astrophysics Data System (ADS)
Kasmuri, Norhafezah; Ashikin Mat Damin, Nur; Omar, Megawati
2018-02-01
Untreated landfill leachate is known to have endangered the environment. As such new treatment must be sought to ensure its cost-effective and sustainable treatment. Thus this paper reports the effectiveness of bio-filter to remove pollutants. In this research, the reduction of nutrients concentration was evaluated in two conditions: using bio-filter and without bio-filter. Synthetic wastewater was used in the batch culture. It was conducted within 21 days in the initial mediums of 100 mg/L ammonia-nitrogen. The nitrification medium consisted of 100 mg/L of ammonia-nitrogen while the nitrite assay had none. The petri dish experiment was also conducted to observe the existence of any colony. The results showed 22% of ammonia- nitrogen reduction and 33% phosphate in the nitrification medium with the bio-filter. The outcome showed that the bio-filter was capable to reduce the concentration of pollutants by retaining the slow growing bacteria (AOB and NOB) on the plastic carrier surface. The factorial design was applied to study the effect of the initial ammonia-nitrogen concentration and duration on nitrite-nitrogen removal. Finally, a regression equation was produced to predict the rate of nitrite-nitrogen removal without conducting extended experiments and to reduce the number of trials experiment.
Adaptive Estimation of Multiple Fading Factors for GPS/INS Integrated Navigation Systems.
Jiang, Chen; Zhang, Shu-Bi; Zhang, Qiu-Zhao
2017-06-01
The Kalman filter has been widely applied in the field of dynamic navigation and positioning. However, its performance will be degraded in the presence of significant model errors and uncertain interferences. In the literature, the fading filter was proposed to control the influences of the model errors, and the H-infinity filter can be adopted to address the uncertainties by minimizing the estimation error in the worst case. In this paper, a new multiple fading factor, suitable for the Global Positioning System (GPS) and the Inertial Navigation System (INS) integrated navigation system, is proposed based on the optimization of the filter, and a comprehensive filtering algorithm is constructed by integrating the advantages of the H-infinity filter and the proposed multiple fading filter. Measurement data of the GPS/INS integrated navigation system are collected under actual conditions. Stability and robustness of the proposed filtering algorithm are tested with various experiments and contrastive analysis are performed with the measurement data. Results demonstrate that both the filter divergence and the influences of outliers are restrained effectively with the proposed filtering algorithm, and precision of the filtering results are improved simultaneously.
Irrelevant Singletons in Pop-Out Search: Attentional Capture or Filtering Costs?
ERIC Educational Resources Information Center
Becker, Stefanie I.
2007-01-01
The aim of the present study was to investigate whether costs invoked by the presence of an irrelevant singleton distractor in a visual search task are due to attentional capture by the irrelevant singleton or spatially unrelated filtering costs. Measures of spatial effects were based on distance effects, compatibility effects, and differences…
Ecotoxicity of two organic UV-filters to the freshwater caddisfly Sericostoma vittatum.
Campos, Diana; Gravato, Carlos; Fedorova, Ganna; Burkina, Viktoriia; Soares, Amadeu M V M; Pestana, João L T
2017-09-01
Organic ultraviolet filters (UV-filters) used for protection against radiation in personal care products and other materials (e.g. textiles, plastic products) are considered emerging contaminants of aquatic ecosystem. Benzophenone-3 (BP3) and 3-(4-methylbenzylidene)camphor (4-MBC) are the most commonly used organic UV-filters and have been reported in freshwater environments due to contamination through discharges from wastewater treatment plants and swimming pools or by direct contamination from recreational activities. Our aim was to evaluate the ecotoxicological effects of these UV-filters using the freshwater caddisfly Sericostoma vittatum' biochemical biomarkers and energy processing related endpoints (feeding behaviour, energy reserves and cellular metabolism). In laboratory trials, both compounds induced feeding inhibition of S. vittatum at 3.55 mg/kg of BP3 and at concentrations ≥2.57 mg/kg of 4-MBC, decreased carbohydrates content at 3.55 and 6.95 mg/kg of BP3 and 4-MBC respectively, and increased total glutathione levels at concentrations ≥1.45 and 1.35 mg/kg of BP3 and 4-MBC respectively. No significant effects were observed on endpoints associated with oxidative stress, antioxidant defences, phase II biotransformation or neurotoxicity after exposure to the two UV-filters. Our results show that environmental relevant concentrations of BP3 and 4-MBC, can negatively impact freshwater insects and demonstrate the importance of monitoring the ecological effects of organic UV-filters using non-model invertebrate species. Copyright © 2017 Elsevier Ltd. All rights reserved.
Motegi, Toshinori; Nabika, Hideki; Fu, Yingqiang; Chen, Lili; Sun, Yinlu; Zhao, Jianwei; Murakoshi, Kei
2014-07-01
A new molecular manipulation method in the self-spreading lipid bilayer membrane by combining Brownian ratchet and molecular filtering effects is reported. The newly designed ratchet obstacle was developed to effectively separate dye-lipid molecules. The self-spreading lipid bilayer acted as both a molecular transport system and a manipulation medium. By controlling the size and shape of ratchet obstacles, we achieved a significant increase in the separation angle for dye-lipid molecules compared to that with the previous ratchet obstacle. A clear difference was observed between the experimental results and the simple random walk simulation that takes into consideration only the geometrical effect of the ratchet obstacles. This difference was explained by considering an obstacle-dependent local decrease in molecular diffusivity near the obstacles, known as the molecular filtering effect at nanospace. Our experimental findings open up a novel controlling factor in the Brownian ratchet manipulation that allow the efficient separation of molecules in the lipid bilayer based on the combination of Brownian ratchet and molecular filtering effects.
Wang, Hongyu; He, Jiajie; Yang, Kai
2010-01-01
This study evaluated the partial nitrification performances of two biofilm filters over a synthetic non-ammonium-rich wastewater at a 20°C room temperature under both limited DO (∼2.0 mg/L) and unlimited DO (∼4.0 mg/L) conditions. The two filters were each of 80 cm long and used different biofilm carriers: activated carbon and ceramic granule. Results showed that partial nitrification was accomplished for both filters under the limited DO condition. However, the effluent NO(2)-N was higher in the ceramic granule filter than in the activated carbon filter, and was less susceptible to the influent COD/N changes. Further investigation into the water phase COD and NH(4)-N depth profiles and bacteria population within the two filters showed that by putting upper filter layer (upstream) to confront relatively higher influent COD/N ratios, the filtration process naturally put lower filter layers (downstream) relatively more favorable for nitrifying bacteria (ammonia oxidizing bacteria in this study) to prosper, making the filter depth left for nitrification a crucial factor for the effectiveness of nitrification with a filter. The potentially different porous flow velocities of the two filters might be the reason to cause their different partial nitrification performances, with a lower porous flow velocity (the ceramic granule filter) favoring partial nitrification more. In summation, DO, filter depth, and filtration speed should be played together to successfully operate a biofilm filter for partial nitrification.
Parallel Digital Phase-Locked Loops
NASA Technical Reports Server (NTRS)
Sadr, Ramin; Shah, Biren N.; Hinedi, Sami M.
1995-01-01
Wide-band microwave receivers of proposed type include digital phase-locked loops in which band-pass filtering and down-conversion of input signals implemented by banks of multirate digital filters operating in parallel. Called "parallel digital phase-locked loops" to distinguish them from other digital phase-locked loops. Systems conceived as cost-effective solution to problem of filtering signals at high sampling rates needed to accommodate wide input frequency bands. Each of M filters process 1/M of spectrum of signal.
Ke He; Anne Timm; Lee Blaney
2017-01-01
tUltraviolet-filters (UV-filters) and estrogens have attracted increased attention as contaminants of emerging concern (CECs) due to their widespread occurrence in the environment. Most of these CECs are hydrophobic and have the potential to accumulate in aquatic organisms. To date, co-analysis of UV-filters and estrogens has not been reported due, in part, to the...
Tunable-optical-filter-based white-light interferometry for sensing.
Yu, Bing; Wang, Anbo; Pickrell, Gary; Xu, Juncheng
2005-06-15
We describe tunable-optical-filter-based white-light interferometry for sensor interrogation. By introducing a tunable optical filter into a white-light interferometry system, one can interrogate an interferometer with either quadrature demodulation or spectral-domain detection at low cost. To demonstrate the feasibility of effectively demodulating various types of interferometric sensor, experiments have been performed using an extrinsic Fabry-Perot tunable filter to interrogate two extrinsic Fabry-Perot interferometric temperature sensors and a diaphragm-based pressure sensor.
FIR Filter of DS-CDMA UWB Modem Transmitter
NASA Astrophysics Data System (ADS)
Kang, Kyu-Min; Cho, Sang-In; Won, Hui-Chul; Choi, Sang-Sung
This letter presents low-complexity digital pulse shaping filter structures of a direct sequence code division multiple access (DS-CDMA) ultra wide-band (UWB) modem transmitter with a ternary spreading code. The proposed finite impulse response (FIR) filter structures using a look-up table (LUT) have the effect of saving the amount of memory by about 50% to 80% in comparison to the conventional FIR filter structures, and consequently are suitable for a high-speed parallel data process.
Manga, M; Evans, B E; Camargo-Valero, M A; Horan, N J
2016-12-01
The effect of sand filter media thickness on the performance of faecal sludge (FS) drying beds was determined in terms of: dewatering time, contaminant load removal efficiency, solids generation rate, nutrient content and helminth eggs viability in the dried sludge. A mixture of ventilated improved pit latrine sludge and septage in the ratio 1:2 was dewatered using three pilot-scale sludge drying beds with sand media thicknesses of 150, 250 and 350 mm. Five dewatering cycles were conducted and monitored for each drying bed. Although the 150 mm filter had the shortest average dewatering time of 3.65 days followed by 250 mm and 350 mm filters with 3.83 and 4.02 days, respectively, there was no significant difference (p > 0.05) attributable to filter media thickness configurations. However, there was a significant difference for the percolate contaminant loads in the removal and recovery efficiency of suspended solids, total solids, total volatile solids, nitrogen species, total phosphorus, chemical oxygen demand, dissolved chemical oxygen demand and biochemical oxygen demand, with the highest removal efficiency for each parameter achieved by the 350 mm filter. There were also significant differences in the nutrient content (NPK) and helminth eggs viability of the solids generated by the tested filters. Filtering media configurations similar to 350 mm have the greatest potential for optimising nutrient recovery from FS.
Initial experience using the rigid forceps technique to remove wall-embedded IVC filters.
Avery, Allan; Stephens, Maximilian; Redmond, Kendal; Harper, John
2015-06-01
Severely tilted and embedded inferior vena cava (IVC) filters remain the most challenging IVC filters to remove. Heavy endothelialisation over the filter hook can prevent engagement with standard snare and cone recovery techniques. The rigid forceps technique offers a way to dissect the endothelial cap and reliably retrieve severely tilted and embedded filters. By developing this technique, failed IVC retrieval rates can be significantly reduced and the optimum safety profile offered by temporary filters can be achieved. We present our initial experience with the rigid forceps technique described by Stavropoulos et al. for removing wall-embedded IVC filters. We retrospectively reviewed the medical imaging and patient records of all patients who underwent a rigid forceps filter removal over a 22-month period across two tertiary referral institutions. The rigid forceps technique had a success rate of 85% (11/13) for IVC filter removals. All filters in the series showed evidence of filter tilt and embedding of the filter hook into the IVC wall. Average filter tilt from the Z-axis was 19 degrees (range 8-56). Filters observed in the case study were either Bard G2X (n = 6) or Cook Celect (n = 7). Average filter dwell time was 421 days (range 47-1053). There were no major complications observed. The rigid forceps technique can be readily emulated and is a safe and effective technique to remove severely tilted and embedded IVC filters. The development of this technique across both institutions has increased the successful filter removal rate, with perceived benefits to the safety profile of our IVC filter programme. © 2015 The Royal Australian and New Zealand College of Radiologists.
NASA Astrophysics Data System (ADS)
Floberg, J. M.; Holden, J. E.
2013-02-01
We introduce a method for denoising dynamic PET data, spatio-temporal expectation-maximization (STEM) filtering, that combines four-dimensional Gaussian filtering with EM deconvolution. The initial Gaussian filter suppresses noise at a broad range of spatial and temporal frequencies and EM deconvolution quickly restores the frequencies most important to the signal. We aim to demonstrate that STEM filtering can improve variance in both individual time frames and in parametric images without introducing significant bias. We evaluate STEM filtering with a dynamic phantom study, and with simulated and human dynamic PET studies of a tracer with reversible binding behaviour, [C-11]raclopride, and a tracer with irreversible binding behaviour, [F-18]FDOPA. STEM filtering is compared to a number of established three and four-dimensional denoising methods. STEM filtering provides substantial improvements in variance in both individual time frames and in parametric images generated with a number of kinetic analysis techniques while introducing little bias. STEM filtering does bias early frames, but this does not affect quantitative parameter estimates. STEM filtering is shown to be superior to the other simple denoising methods studied. STEM filtering is a simple and effective denoising method that could be valuable for a wide range of dynamic PET applications.
Fabrication of TiO2/EP super-hydrophobic thin film on filter paper surface.
Gao, Zhengxin; Zhai, Xianglin; Liu, Feng; Zhang, Ming; Zang, Deli; Wang, Chengyu
2015-09-05
A composite filter paper with super-hydrophobicity was obtained by adhering micro/nano structure of amorphous titanium dioxide on the filter paper surface with modifying low surface energy material. By virtue of the coupling agent, which plays an important part in bonding amorphous titanium dioxide and epoxy resin, the structure of super-hydrophobic thin film on the filter paper surface is extremely stable. The microstructure of super-hydrophobic filter paper was characterized by scanning electron microscopy (SEM), the images showed that the as-prepared filter paper was covered with uniform amorphous titanium dioxide particles, generating a roughness structure on the filter paper surface. The super-hydrophobic performance of the filter paper was characterized by water contact angle measurements. The observations showed that the wettability of filter paper samples transformed from super-hydrophilicity to super-hydrophobicity with the water contact angle of 153 ± 1°. Some experiments were also designed to test the effect of water-oil separation and UV-resistant by the super-hydrophobic filter paper. The prepared super-hydrophobic filter paper worked efficiently and simply in water-oil separation as well as enduringly in anti-UV property after the experiments. This method offers an opportunity to the practical applications of the super-hydrophobic filter paper. Copyright © 2015 Elsevier Ltd. All rights reserved.
Influence of size, shape, and flexibility on bacterial passage through micropore membrane filters.
Wang, Yingying; Hammes, Frederik; Düggelin, Marcel; Egli, Thomas
2008-09-01
Sterilization of fluids by means of microfiltration is commonly applied in research laboratories as well as in pharmaceutical and industrial processes. Sterile micropore filters are subject to microbiological validation, where Brevundimonas diminuta is used as a standard test organism. However, several recent reports on the ubiquitous presence of filterable bacteria in aquatic environments have cast doubt on the accuracy and validity of the standard filter-testing method. Six different bacterial species of various sizes and shapes (Hylemonella gracilis, Escherichia coli, Sphingopyxis alaskensis, Vibrio cholerae, Legionella pneumophila, and B. diminuta) were tested for their filterability through sterile micropore filters. In all cases, the slender spirillum-shaped Hylemonella gracilis cells showed a superior ability to pass through sterile membrane filters. Our results provide solid evidence that the overall shape (including flexibility), instead of biovolume, is the determining factor for the filterability of bacteria, whereas cultivation conditions also play a crucial role. Furthermore, the filtration volume has a more important effect on the passage percentage in comparison with other technical variables tested (including flux and filter material). Based on our findings, we recommend a re-evaluation of the grading system for sterile filters, and suggest that the species Hylemonella should be considered as an alternative filter-testing organism for the quality assessment of micropore filters.
Examination of pulverized waste recycled glass as filter media in slow sand filtration. Final report
DOE Office of Scientific and Technical Information (OSTI.GOV)
Piccirillo, J.B.; Letterman, R.D.
1997-10-01
The purpose of this study was to investigate the pulverization of waste recycled glass to produce glass sand for slow sand filters. Pulverization experiments were performed using a fail mill pulverizer. The glass sand product from the pulverizer meets the size distribution requirements of ASTM-C-33 without size distribution adjustment. The size distribution must be adjusted to meet the grain size distribution requirements of the Ten States Standards and the USEPA for filter media used in slow sand filters. Pulverized glass that meet slow sand filter media specifications is an effective alternative to silica sand as a filter media for slowmore » sand filtration. Three pilot plant slow sand filters with glass sand filter media were compared to a fourth filter containing silica sand filter media. Over an 8 month period of continuous operation, the performance of the glass sand filter media was as good or better than the silica sands, with removals of 56% to 96% for turbidity; 99.78% to 100.0% for coliform bacteria; 99.995% to 99.997% for giardia cysts; 99.92% and 99.97% for cryptosporidium oocysts. Based on a cost-benefit analysis, converting waste glass into filter media may be economically advantageous for recycling facilities.« less
Fransz, Duncan P; Huurnink, Arnold; de Boode, Vosse A; Kingma, Idsart; van Dieën, Jaap H
2015-01-01
Time to stabilization (TTS) is the time it takes for an individual to return to a baseline or stable state following a jump or hop landing. A large variety exists in methods to calculate the TTS. These methods can be described based on four aspects: (1) the input signal used (vertical, anteroposterior, or mediolateral ground reaction force) (2) signal processing (smoothed by sequential averaging, a moving root-mean-square window, or fitting an unbounded third order polynomial), (3) the stable state (threshold), and (4) the definition of when the (processed) signal is considered stable. Furthermore, differences exist with regard to the sample rate, filter settings and trial length. Twenty-five healthy volunteers performed ten 'single leg drop jump landing' trials. For each trial, TTS was calculated according to 18 previously reported methods. Additionally, the effects of sample rate (1000, 500, 200 and 100 samples/s), filter settings (no filter, 40, 15 and 10 Hz), and trial length (20, 14, 10, 7, 5 and 3s) were assessed. The TTS values varied considerably across the calculation methods. The maximum effect of alterations in the processing settings, averaged over calculation methods, were 2.8% (SD 3.3%) for sample rate, 8.8% (SD 7.7%) for filter settings, and 100.5% (SD 100.9%) for trial length. Differences in TTS calculation methods are affected differently by sample rate, filter settings and trial length. The effects of differences in sample rate and filter settings are generally small, while trial length has a large effect on TTS values. Copyright © 2014 Elsevier B.V. All rights reserved.
Ozáez, Irene; Aquilino, Mónica; Morcillo, Gloria; Martínez-Guitarte, José-Luis
2016-07-01
Organic ultraviolet (UV) filters are emerging contaminants that are ubiquitous in fresh and marine aquatic systems due to their extensive use in cosmetics, plastics, paints, textiles, and many other industrial products. The estrogenic effects of organic UV filters have been long demonstrated in vertebrates, and other hormonal activities may be altered, according to more recent reports. The impact of UV filters on the endocrine system of invertebrates is largely unknown. We have previously reported that some UV filters may affect ecdysone-related genes in the aquatic insect Chironomus riparius, an ecotoxicologically important model organism. To further analyze other possible effects on endocrine pathways, we first characterized four pivotal genes related with hormonal pathways in insects; thereafter, these genes were assessed for alterations in transcriptional activity after exposure to 4-methylbenzylidene camphor (4MBC) or benzophenone-3 (BP-3), two extensively used sunscreens. We found that both chemicals disturbed the expression of all four genes analyzed: hormonal receptor 38 (HR38), methoprene-tolerant (Met), membrane-associate progesterone receptor (MAPR) and insulin-like receptor (INSR), measured by changes in mRNA levels by real-time PCR. An upregulatory effect at the genomic level was detected in different developmental stages. Interestingly, embryos appeared to be more sensitive to the action of the UV filters than larvae. Our results suggest that the risk of disruption through different endocrine routes is not negligible, considering the significant effects of UV filters on key hormonal receptor and regulatory genes. Further effort is needed to develop environmental risk assessment studies on these pollutants, particularly for aquatic invertebrate model organisms. Copyright © 2016 Elsevier Ltd. All rights reserved.
Moyer, E S; Bergman, M S
2000-08-01
The effects of intermittently loading small masses of sodium chloride aerosol on the filtration efficiency of N-95 filtering facepiece respirators was investigated. The National Institute for Occupational Safety and Health (NIOSH) certifies that N-95 respirators must provide at least 95 percent filtration efficiency against a sodium chloride aerosol challenge as per the respirator certification (42 CFR 84) test criteria. N-95 respirators are specified for protection against solid and water-based particulates (i.e., non-oil aerosols). New N-95 respirators from three different manufacturers were loaded with 5 +/- 1 mg of sodium chloride aerosol one day a week, over a period of weeks. Aerosol loading and penetration measurements were performed using the TSI 8130 Filter Tester. Respirators were stored uncovered on an office desktop outside the laboratory. To investigate environmental and temporal effects of filters being stored without sodium chloride exposure, control respirators were stored on the desk for various lengths of time before being initiated into weekly testing. For all manufacturers' respirators, the controls showed similar initial penetrations on their day of initiation (day zero) to those of the study samples on day zero. As the controls were tested weekly, they showed similar degradation rates to those of the study samples. Results show that some of the manufacturers' models had penetrations of greater than 5 percent when intermittently exposed to sodium chloride aerosol. It is concluded that intermittent, low-level sodium chloride aerosol loading of N-95 respirators has a degrading effect on filter efficiency. This reduction in filter efficiency was not accompanied by a significant increase in breathing resistance that would signal the user that the filter needs to be replaced. Furthermore, it was noted that the effect of room storage time prior to initial exposure was much less significant.