Sample records for finnic case forms

  1. INTRODUCTION TO ESTONIAN LINGUISTICS.

    ERIC Educational Resources Information Center

    RAUN, ALO; SAARESTE, ANDRUS

    THIS TEXT COMPRISES A SURVEY OF THE ESTONIAN LANGUAGE, WHICH IS GROUPED HERE WITH LIVONIAN, VOTIC, AND A PART OF WESTERN FINNISH, TO FORM THE SOUTHWESTERN BRANCH OF THE FINNIC (OR BALTO-FINNIC) LANGUAGES. THE AUTHORS' CLASSIFICATIONS AND A HISTORY OF THE STUDIES WHICH HAVE BEEN CARRIED OUT IN ESTONIAN ARE PRESENTED, FOLLOWED BY A PRESENTATION OF…

  2. A Genome-Wide Analysis of Populations from European Russia Reveals a New Pole of Genetic Diversity in Northern Europe

    PubMed Central

    Khrunin, Andrey V.; Khokhrin, Denis V.; Filippova, Irina N.; Esko, Tõnu; Nelis, Mari; Bebyakova, Natalia A.; Bolotova, Natalia L.; Klovins, Janis; Nikitina-Zake, Liene; Rehnström, Karola; Ripatti, Samuli; Schreiber, Stefan; Franke, Andre; Macek, Milan; Krulišová, Veronika; Lubinski, Jan; Metspalu, Andres; Limborska, Svetlana A.

    2013-01-01

    Several studies examined the fine-scale structure of human genetic variation in Europe. However, the European sets analyzed represent mainly northern, western, central, and southern Europe. Here, we report an analysis of approximately 166,000 single nucleotide polymorphisms in populations from eastern (northeastern) Europe: four Russian populations from European Russia, and three populations from the northernmost Finno-Ugric ethnicities (Veps and two contrast groups of Komi people). These were compared with several reference European samples, including Finns, Estonians, Latvians, Poles, Czechs, Germans, and Italians. The results obtained demonstrated genetic heterogeneity of populations living in the region studied. Russians from the central part of European Russia (Tver, Murom, and Kursk) exhibited similarities with populations from central–eastern Europe, and were distant from Russian sample from the northern Russia (Mezen district, Archangelsk region). Komi samples, especially Izhemski Komi, were significantly different from all other populations studied. These can be considered as a second pole of genetic diversity in northern Europe (in addition to the pole, occupied by Finns), as they had a distinct ancestry component. Russians from Mezen and the Finnic-speaking Veps were positioned between the two poles, but differed from each other in the proportions of Komi and Finnic ancestries. In general, our data provides a more complete genetic map of Europe accounting for the diversity in its most eastern (northeastern) populations. PMID:23505534

  3. Noun and verb knowledge in monolingual preschool children across 17 languages: Data from Cross-linguistic Lexical Tasks (LITMUS-CLT).

    PubMed

    Haman, Ewa; Łuniewska, Magdalena; Hansen, Pernille; Simonsen, Hanne Gram; Chiat, Shula; Bjekić, Jovana; Blažienė, Agnė; Chyl, Katarzyna; Dabašinskienė, Ineta; Engel de Abreu, Pascale; Gagarina, Natalia; Gavarró, Anna; Håkansson, Gisela; Harel, Efrat; Holm, Elisabeth; Kapalková, Svetlana; Kunnari, Sari; Levorato, Chiara; Lindgren, Josefin; Mieszkowska, Karolina; Montes Salarich, Laia; Potgieter, Anneke; Ribu, Ingeborg; Ringblom, Natalia; Rinker, Tanja; Roch, Maja; Slančová, Daniela; Southwood, Frenette; Tedeschi, Roberta; Tuncer, Aylin Müge; Ünal-Logacev, Özlem; Vuksanović, Jasmina; Armon-Lotem, Sharon

    2017-01-01

    This article investigates the cross-linguistic comparability of the newly developed lexical assessment tool Cross-linguistic Lexical Tasks (LITMUS-CLT). LITMUS-CLT is a part the Language Impairment Testing in Multilingual Settings (LITMUS) battery (Armon-Lotem, de Jong & Meir, 2015). Here we analyse results on receptive and expressive word knowledge tasks for nouns and verbs across 17 languages from eight different language families: Baltic (Lithuanian), Bantu (isiXhosa), Finnic (Finnish), Germanic (Afrikaans, British English, South African English, German, Luxembourgish, Norwegian, Swedish), Romance (Catalan, Italian), Semitic (Hebrew), Slavic (Polish, Serbian, Slovak) and Turkic (Turkish). The participants were 639 monolingual children aged 3;0-6;11 living in 15 different countries. Differences in vocabulary size were small between 16 of the languages; but isiXhosa-speaking children knew significantly fewer words than speakers of the other languages. There was a robust effect of word class: accuracy was higher for nouns than verbs. Furthermore, comprehension was more advanced than production. Results are discussed in the context of cross-linguistic comparisons of lexical development in monolingual and bilingual populations.

  4. Cultural and climatic changes shape the evolutionary history of the Uralic languages.

    PubMed

    Honkola, T; Vesakoski, O; Korhonen, K; Lehtinen, J; Syrjänen, K; Wahlberg, N

    2013-06-01

    Quantitative phylogenetic methods have been used to study the evolutionary relationships and divergence times of biological species, and recently, these have also been applied to linguistic data to elucidate the evolutionary history of language families. In biology, the factors driving macroevolutionary processes are assumed to be either mainly biotic (the Red Queen model) or mainly abiotic (the Court Jester model) or a combination of both. The applicability of these models is assumed to depend on the temporal and spatial scale observed as biotic factors act on species divergence faster and in smaller spatial scale than the abiotic factors. Here, we used the Uralic language family to investigate whether both 'biotic' interactions (i.e. cultural interactions) and abiotic changes (i.e. climatic fluctuations) are also connected to language diversification. We estimated the times of divergence using Bayesian phylogenetics with a relaxed-clock method and related our results to climatic, historical and archaeological information. Our timing results paralleled the previous linguistic studies but suggested a later divergence of Finno-Ugric, Finnic and Saami languages. Some of the divergences co-occurred with climatic fluctuation and some with cultural interaction and migrations of populations. Thus, we suggest that both 'biotic' and abiotic factors contribute either directly or indirectly to the diversification of languages and that both models can be applied when studying language evolution. © 2013 The Authors. Journal of Evolutionary Biology © 2013 European Society For Evolutionary Biology.

  5. 76 FR 61725 - Agency Information Collection Activities: Case Submission Form, Case Assistance Form; (Form DHS...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-05

    ..., Case Assistance Form; (Form DHS-7001), Online Ombudsman Form DHS-7001 AGENCY: Office of the Citizenship... System'' to ``Online Ombudsman Form DHS-7001''. The instructions have been updated to reflect the... Services Ombudsman--001 Virtual Ombudsman System (March 2010) to reflect the name change to Online...

  6. 75 FR 6671 - Agency Forms Undergoing Paperwork Reduction Act Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-10

    ... Project Congenital Syphilis (CS) Case Investigation and Report Form (CDC73.126), OMB No. 0920-0128, (exp... ``Congenital Syphilis (CS) Case Investigation and Report Form'' (CDC73.126). The CS Form is currently approved... Health Departments Congenital Syphilis (CS) 10 11 20/60 Case Investigation and Report. Territorial Health...

  7. Leveraging public health's participation in a Health Information Exchange to improve communicable disease reporting.

    PubMed

    Painter, Ian; Revere, Debra; Gibson, P Joseph; Baseman, Janet

    2017-01-01

    Infectious diseases can appear and spread rapidly. Timely information about disease patterns and trends allows public health agencies to quickly investigate and efficiently contain those diseases. But disease case reporting to public health has traditionally been paper-based, resulting in somewhat slow, burdensome processes. Fortunately, the expanding use of electronic health records and health information exchanges has created opportunities for more rapid, complete, and easily managed case reporting and investigation. To assess how this new service might impact the efficiency and quality of a public health agency's case investigations, we compared the timeliness of usual case investigation to that of case investigations based on case report forms that were partially pre-populated with electronic data. Between September 2013-March 2014, chlamydia disease report forms for certain clinics in Indianapolis were electronically pre-populated with clinical, lab and patient data available through the Indiana Health Information Exchange, then provided to the patient’s doctor. Doctors could then sign the form and deliver it to public health for investigation and population-level disease tracking. Methods: We utilized a novel matched case analysis of timeliness changes in receipt and processing of communicable disease report forms. Each Chlamydia cases reported with the pre-populated form were matched to cases reported in usual ways. We assessed the time from receipt of the case at the public health agency: 1) inclusion of the case into the public health surveillance system and 2) to close to case. A hierarchical random effects model was used to compare mean difference in each outcome between the target cases and the matched cases, with random intercepts for case. Twenty-one Chlamydia cases were reported to the public health agency using the pre-populated form. Sixteen of these pre-populated form cases were matched to at least one other case, with a mean of 23 matches per case. The mean Reporting Lag for the pre-populated form cases was 2.5 days, which was 2.7 days shorter than the mean Reporting Lag for the matched controls (p = <0.001). The mean time to close a pre-populated form case was 4.7 days, which was 0.2 days shorter than time to close for the matched controls (p = 0.792). Use of pre-populated forms significantly decreased the time it took for the local public health agency to begin documenting and closing chlamydia case investigations. Thoughtful use of electronic health data for case reporting may decrease the per-case workload of public health agencies, and improve the timeliness of information about the pattern and spread of disease.

  8. MRI and clinical features of maple syrup urine disease: preliminary results in 10 cases.

    PubMed

    Cheng, Ailan; Han, Lianshu; Feng, Yun; Li, Huimin; Yao, Rong; Wang, Dengbin; Jin, Biao

    2017-01-01

    We aimed to evaluate the magnetic resonance imaging (MRI) and clinical features of maple syrup urine disease (MSUD). This retrospective study consisted of 10 MSUD patients confirmed by genetic testing. All patients underwent brain MRI. Phenotype, genotype, and areas of brain injury on MRI were retrospectively reviewed. Six patients (60%) had the classic form of MSUD with BCKDHB mutation, three patients (30%) had the intermittent form (two with BCKDHA mutations and one with DBT mutation), and one patient (10%) had the thiamine-responsive form with DBT mutation. On diffusion-weighted imaging, nine cases presented restricted diffusion in myelinated areas, and one intermittent case with DBT mutation was normal. The classic form of MSUD involved the basal ganglia in six cases; the cerebellum, mesencephalon, pons, and supratentorial area in five cases; and the thalamus in four cases, respectively. The intermittent form involved the cerebellum, pons, and supratentorial area in two cases. The thiamine-responsive form involved the basal ganglia and supratentorial area. Our preliminary results indicate that patients with MSUD presented more commonly in classic form with BCKDHB mutation and displayed extensive brain injury on MRI.

  9. MRI and clinical features of maple syrup urine disease: preliminary results in 10 cases

    PubMed Central

    Cheng, Ailan; Han, Lianshu; Feng, Yun; Li, Huimin; Yao, Rong; Wang, Dengbin; Jin, Biao

    2017-01-01

    PURPOSE We aimed to evaluate the magnetic resonance imaging (MRI) and clinical features of maple syrup urine disease (MSUD). METHODS This retrospective study consisted of 10 MSUD patients confirmed by genetic testing. All patients underwent brain MRI. Phenotype, genotype, and areas of brain injury on MRI were retrospectively reviewed. RESULTS Six patients (60%) had the classic form of MSUD with BCKDHB mutation, three patients (30%) had the intermittent form (two with BCKDHA mutations and one with DBT mutation), and one patient (10%) had the thiamine-responsive form with DBT mutation. On diffusion-weighted imaging, nine cases presented restricted diffusion in myelinated areas, and one intermittent case with DBT mutation was normal. The classic form of MSUD involved the basal ganglia in six cases; the cerebellum, mesencephalon, pons, and supratentorial area in five cases; and the thalamus in four cases, respectively. The intermittent form involved the cerebellum, pons, and supratentorial area in two cases. The thiamine-responsive form involved the basal ganglia and supratentorial area. CONCLUSION Our preliminary results indicate that patients with MSUD presented more commonly in classic form with BCKDHB mutation and displayed extensive brain injury on MRI. PMID:28830848

  10. Device for temporarily closing duct-formers in well completion apparatus

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zandmer, H.M.; Zandmer, S.M.

    A duct-forming device is disclosed for use in a well completion apparatus of the kind, wherein a bore hole casing is positioned in a bore hole and duct-forming devices of alkali- and acid resistant metal-such as steel-are secured at spaced levels to the casing in alignment with holes machined in the casing wall. In accordance with the invention, a closure device is arranged within the duct-forming device which permits flow of predetermined amounts of liquid, such as acid, from the interior of the casing through the duct-forming device and into the producing formation, while gradually being moved by the liquidmore » into a position in which such fluid flow is prevented. After the fluid flow has been stopped by the closure device and when the formation pressure exceeds the pressure within the duct-forming device and the casing, fluid from the formation then forces the closure device toward and into the casing space to permit thereafter free flow of formation fluid into the duct-forming device and the casing or of pressurized treatment liquid from the casing into the formation. The inventive arrangement permits inter alia the establishment of a sufficient and substantially uniform feeding rate of treatment liquid, such as acid, from the casing into the producing formation through all the duct-formers in preparation for subsequent acidification or other treatments, such as sand fracking.« less

  11. 77 FR 39346 - Proposed Information Collection (Statement of Accredited Representative in Appealed Case, VA Form...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-02

    ... in Appealed Case, VA Form 646. OMB Control Number: 2900-0042. Type of Review: Extension of a... (Statement of Accredited Representative in Appealed Case, VA Form 646) Activity: Comment Request AGENCY: The Board of Veterans' Appeals (BVA), Department of Veterans Affairs. ACTION: Notice. SUMMARY: The Board of...

  12. [Generalized congenital fibromatosis (author's transl)].

    PubMed

    Larrègue, M; Poitou, C; Bressieux, J P; de Giacomoni, P; Vant, F

    1977-05-01

    About a spontaneously regressive case of osteo-cutaneous congenital fibromatosis, the authors describe the characteristics of the disease (32 observations). Although the majority of cases are sporadic, 3 familial observations are in favour of a dominant autosomal transmission of low penetrance. Study of the familial cases and analysis of the different localisations demonstrate the unicity of the so-called diffuse forms with visceral involvement and of the so-called generalized forms without visceral involvement congenital fibromatosis is characterized by several fibromas at birth: in two-thirds of the cases, it is a purely cutaneous or osteocutaneous form, which disappears spontaneously; in one third of the cases, it is a cutaneous or osteo-cutaneous form with lethal visceral involvement.

  13. 26 CFR 1.6411-1 - Tentative carryback adjustments.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... adjustment shall be filed, in the case of a corporation, on Form 1139, and in the case of taxpayers other than corporations, on Form 1045. The application shall be filled out in accordance with the instructions accompanying the form, and all information required by the form and the instructions must be...

  14. 26 CFR 1.6411-1 - Tentative carryback adjustments.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... tentative carryback adjustment shall be filed, in the case of a corporation, on Form 1139, and in the case of taxpayers other than corporations, on Form 1045. The application shall be filled out in accordance with the instructions accompanying the form, and all information required by the form and the...

  15. 26 CFR 1.6411-1 - Tentative carryback adjustments.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... tentative carryback adjustment shall be filed, in the case of a corporation, on Form 1139, and in the case of taxpayers other than corporations, on Form 1045. The application shall be filled out in accordance with the instructions accompanying the form, and all information required by the form and the...

  16. 26 CFR 1.6411-1 - Tentative carryback adjustments.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... tentative carryback adjustment shall be filed, in the case of a corporation, on Form 1139, and in the case of taxpayers other than corporations, on Form 1045. The application shall be filled out in accordance with the instructions accompanying the form, and all information required by the form and the...

  17. 26 CFR 1.6411-1 - Tentative carryback adjustments.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... tentative carryback adjustment shall be filed, in the case of a corporation, on Form 1139, and in the case of taxpayers other than corporations, on Form 1045. The application shall be filled out in accordance with the instructions accompanying the form, and all information required by the form and the...

  18. [Implementation and (cost-)effectiveness of case management for people with dementia and their informal caregivers: results of the COMPAS study].

    PubMed

    van Mierlo, Lisa D; MacNeil-Vroomen, Janet; Meiland, Franka J M; Joling, Karlijn J; Bosmans, Judith E; Dröes, Rose Marie; Moll van Charante, Eric P; de Rooij, Sophia E J A; van Hout, Hein P J

    2016-12-01

    Different forms of case management for dementia have emerged over the past few years. In the COMPAS study (Collaborative dementia care for patients and caregivers study), two prominent Dutch case management forms were studied: the linkage and the integrated care form. Evaluation of the (cost)effectiveness of two dementia case management forms compared to usual care as well as factors that facilitated or impeded their implementation. A mixed methods design with a) a prospective, observational controlled cohort study with 2 years follow-up among 521 dyads of people with dementia and their primary informal caregiver with and without case management; b) interviews with 22 stakeholders on facilitating and impeding factors of the implementation and continuity of the two case management models. Outcome measures were severity and frequency of behavioural problems (NPI) for the person with dementia and mental health complaints (GHQ-12) for the informal caregiver, total met and unmet care needs (CANE) and quality adjusted life years (QALYs). Outcomes showed a better quality of life of informal caregivers in the integrated model compared to the linkage model. Caregivers in the control group reported more care needs than those in both case management groups. The independence of the case management provider in the integrated model facilitated the implementation, while the rivalry between multiple providers in the linkage model impeded the implementation. The costs of care were lower in the linkage model (minus 22 %) and integrated care model (minus 33 %) compared to the control group. The integrated care form was (very) cost-effective in comparison with the linkage form or no case management. The integrated care form is easy to implement.

  19. Subterranean barriers, methods, and apparatuses for forming, inspecting, selectively heating, and repairing same

    DOEpatents

    Nickelson, Reva A.; Sloan, Paul A.; Richardson, John G.; Walsh, Stephanie; Kostelnik, Kevin M.

    2009-04-07

    A subterranean barrier and method for forming same are disclosed, the barrier including a plurality of casing strings wherein at least one casing string of the plurality of casing strings may be affixed to at least another adjacent casing string of the plurality of casing strings through at least one weld, at least one adhesive joint, or both. A method and system for nondestructively inspecting a subterranean barrier is disclosed. For instance, a radiographic signal may be emitted from within a casing string toward an adjacent casing string and the radiographic signal may be detected from within the adjacent casing string. A method of repairing a barrier including removing at least a portion of a casing string and welding a repair element within the casing string is disclosed. A method of selectively heating at least one casing string forming at least a portion of a subterranean barrier is disclosed.

  20. 76 FR 42129 - Agency Information Collection Activities: Case Submission Form, Case Assistance Form

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-18

    ... is in the final phase of development with successful testing of a pilot version conducted in the 4th... will refer case specific issues to the Customer Assistance Office for USCIS for further research, and...

  1. [The clinico-epidemiological characteristics of Powassan encephalitis in the southern Soviet Far East].

    PubMed

    Leonova, G N; Sorokina, M N; Krugliak, S P

    1991-03-01

    The present communication deals with the analysis of 14 cases of Powassan encephalitis. As shown in this study, the course of this infection may be accompanied by symptoms indicating the presence of cerebral and meningeal lesions (in 7 cases meningoencephalitic forms with one fatal outcome and in 2 cases meningeal forms were registered) or take febrile and inapparent forms (5 cases). Powassan encephalitis was found to give characteristic symptoms of cerebellovestibular lesions, differentiating this disease from tick-borne encephalitis (TBE). The cases of mixed infections caused by TBE virus, Powassan encephalitis virus and tick-born Borrelia were found to be possible.

  2. 5 CFR 1320.8 - Agency collection of information responsibilities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... the case of forms, questionnaires, instructions, and other written collections of information sent or... included either on the form, questionnaire or other collection of information, as part of the instructions.... (ii) In the case of forms, questionnaires, instructions, and other written collections of information...

  3. [Writing and publication of a clinical case report].

    PubMed

    Târcoveanu, E; Roca, M; Mihăescu, T

    2011-01-01

    A case report represents a collection of detailed information about an individual patient, written with the purpose to disseminate clinical outcomes, not previously reported. Case reports provide a rich resource for teaching and research in medicine. Despite the limitation of case reports, these are useful to generate new hypothesis for future large scale clinical trials. A clinical case report should be well structured and convey a clear message. Elements of a case report are similar to all forms of medical scientific articles: title, structured abstract, introduction, case report, discussion, conclusion and references. A well written case report with literature support and a detailed description of management of the case has the greatest chances to be published. "Uniform Requirements for Manuscripts to Biomedical Journals" form the basis for most journal instructions regarding content and formatting and should be consulted when journal's instructions don't answer to author's questions. In this paper we present a case report check sheet to use as a form of self-evaluation, prior to submitting the articles.

  4. Prevention of Posttraumatic Contractures with Ketotifen (PERK)

    DTIC Science & Technology

    2016-10-01

    the Peer Reviewed Orthopaedic Research Program (PRORP) Clinical Trial Award (CTA), W81XWH-16-PRORP-CTA, was submitted. Database development and Pre...and Safety Months Identify database and partner – Clinical Research Unit 1-2 Completed Develop Case Report Forms, consent forms 6-12 Case...report forms completed, consent forms pending – 80% completed Develop database and multicenter submission process 12-18 In progress, 30% completed

  5. Child in a Form: The Definition of Normality and Production of Expertise in Teacher Statement Forms--The Case of Northern Finland, 1951-1990

    ERIC Educational Resources Information Center

    Koskela, Anne; Vehkalahti, Kaisa

    2017-01-01

    This article shows the importance of paying attention to the role of professional devices, such as standardised forms, as producers of normality and deviance in the history of education. Our case study focused on the standardised forms used by teachers during child guidance clinic referrals and transfers to special education in northern Finland,…

  6. Tool Mediation in Focus on Form Activities: Case Studies in a Grammar-Exploring Environment

    ERIC Educational Resources Information Center

    Karlstrom, Petter; Cerratto-Pargman, Teresa; Lindstrom, Henrik; Knutsson, Ola

    2007-01-01

    We present two case studies of two different pedagogical tasks in a Computer Assisted Language Learning environment called Grim. The main design principle in Grim is to support "Focus on Form" in second language pedagogy. Grim contains several language technology-based features for exploring linguistic forms (static, rule-based and statistical),…

  7. Occurrence of thyroxine tablet (Thyradin S(®)) - induced liver dysfunction in a patient with subclinical hypothyroidism.

    PubMed

    Kang, Shino; Amino, Nobuyuki; Kudo, Takumi; Nishihara, Eijun; Ito, Mitsuru; Hirokawa, Mitsuyoshi; Miyauchi, Akira; Tamada, Daisuke; Yasuda, Takenori

    2015-01-01

    A 54-year-old woman with subclinical hypothyroidism developed liver dysfunction after increasing dose of levothyroxine (L-T4) in tablet form (Thyradin S(®)) from 25μg to 50μg. Viral hepatitis, autoimmune hepatitis and NASH were ruled out with examinations. After cessation of levothyroxine in 50μg tablet form, liver enzymes gradually returned to normal. She was diagnosed levothyroxine-induced liver injury, based on criteria proposed in DDW-J 2004 workshop. Thyradin S(®) powder 0.01% (here in after referred to as L-T4 in powder form) was tried as an alternative, and liver enzymes have remained within normal range. As for Thyradin S(®) tablet, additives are different for each type of levothyroxine sodium content. The difference of additive is whether Fe2O3 is contained or not: it is not included in Thyradin S(®) 50μg tablet and powder form. Although there are two case reports in the Japanese literature and three case reports in the English literature of liver dysfunction suspected due to L-T4, we cannot find past reports about cases of drug induced liver dysfunction due to Fe2O3 free levothyroxine tablet form. This is a rare case report of drug induced liver injury due to Fe2O3 free levothyroxine tablet form, and administration of L-T4 in powder form may be useful for treatment of cases similar to this one.

  8. Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Standard Reporting and Evaluation Guidelines: Results of a National Institutes of Health Working Group.

    PubMed

    Maverakis, Emanual; Wang, Elizabeth A; Shinkai, Kanade; Mahasirimongkol, Surakameth; Margolis, David J; Avigan, Mark; Chung, Wen-Hung; Goldman, Jennifer; La Grenade, Lois; Pirmohamed, Munir; Shear, Neil H; Tassaeeyakul, Wichittra; Hoetzenecker, Wolfram; Klaewsongkram, Jettanong; Rerkpattanapipat, Ticha; Manuyakorn, Wiparat; Yasuda, Sally Usdin; Sharon, Victoria R; Sukhov, Andrea; Micheletti, Robert; Struewing, Jeff; French, Lars E; Cheng, Michelle Y

    2017-06-01

    Toxic epidermal necrolysis (TEN) and Stevens-Johnson Syndrome (SJS) are rare, acute, life-threatening dermatologic disorders involving the skin and mucous membranes. Research into these conditions is hampered by a lack of standardization of case reporting and data collection. To establish a standardized case report form to facilitate comparisons and maintain data quality based on an international panel of SJS/TEN experts who performed a Delphi consensus-building exercise. The elements presented for committee scrutiny were adapted from previous case report forms and from PubMed literature searches of highly cited manuscripts pertaining to SJS/TEN. The expert opinions and experience of the members of the consensus group were included in the discussion. Overall, 21 out of 29 experts who were invited to participate in the online Delphi exercise agreed to participate. Surveys at each stage were administered via an online survery software tool. For the first 2 Delphi rounds, results were analyzed using the Interpercentile Range Adjusted for Symmetry method and statements that passed consensus formulated a new case report form. For the third Delphi round, the case report form was presented to the committee, who agreed that it was "appropriate and useful" for documenting cases of SJS/TEN, making it more reliable and valuable for future research endeavors. With the consensus of international experts, a case report form for SJS/TEN has been created to help standardize the collection of patient information in future studies and the documentation of individual cases.

  9. Prescribing Errors Involving Medication Dosage Forms

    PubMed Central

    Lesar, Timothy S

    2002-01-01

    CONTEXT Prescribing errors involving medication dose formulations have been reported to occur frequently in hospitals. No systematic evaluations of the characteristics of errors related to medication dosage formulation have been performed. OBJECTIVE To quantify the characteristics, frequency, and potential adverse patient effects of prescribing errors involving medication dosage forms . DESIGN Evaluation of all detected medication prescribing errors involving or related to medication dosage forms in a 631-bed tertiary care teaching hospital. MAIN OUTCOME MEASURES Type, frequency, and potential for adverse effects of prescribing errors involving or related to medication dosage forms. RESULTS A total of 1,115 clinically significant prescribing errors involving medication dosage forms were detected during the 60-month study period. The annual number of detected errors increased throughout the study period. Detailed analysis of the 402 errors detected during the last 16 months of the study demonstrated the most common errors to be: failure to specify controlled release formulation (total of 280 cases; 69.7%) both when prescribing using the brand name (148 cases; 36.8%) and when prescribing using the generic name (132 cases; 32.8%); and prescribing controlled delivery formulations to be administered per tube (48 cases; 11.9%). The potential for adverse patient outcome was rated as potentially “fatal or severe” in 3 cases (0.7%), and “serious” in 49 cases (12.2%). Errors most commonly involved cardiovascular agents (208 cases; 51.7%). CONCLUSIONS Hospitalized patients are at risk for adverse outcomes due to prescribing errors related to inappropriate use of medication dosage forms. This information should be considered in the development of strategies to prevent adverse patient outcomes resulting from such errors. PMID:12213138

  10. Portable appliance security apparatus

    NASA Technical Reports Server (NTRS)

    Kerley, J. J. (Inventor)

    1981-01-01

    An apparatus for securing a small computer, or other portable appliance, against theft is described. It is comprised of a case having an open back through which the computer is installed or removed. Guide members in the form of slots are formed in a rear portion of opposite walls of the case for receiving a back plate to cover the opening and thereby secure the computer within the case. An opening formed in the top wall of the case exposes the keyboard and display of the computer. The back plate is locked in the closed position by a key-operated plug type lock. The lock is attached to one end of a hold down cable, the opposite end thereof being secured to a desk top or other stationary object. Thus, the lock simultaneously secures the back plate to the case and retains the case to the stationary object.

  11. Stimulus-induced, sleep-bound, focal seizures: a case report.

    PubMed

    Siclari, Francesca; Nobili, Lino; Lo Russo, Giorgio; Moscato, Alessio; Buck, Alfred; Bassetti, Claudio L; Khatami, Ramin

    2011-12-01

    In nocturnal frontal lobe epilepsy (NFLE), seizures occur almost exclusively during NREM sleep. Why precisely these seizures are sleep-bound remains unknown. Studies of patients with nonlesional familial forms of NFLE have suggested the arousal system may play a major role in their pathogenesis. We report the case of a patient with pharmaco-resistant, probably cryptogenic form of non-familial NFLE and strictly sleep-bound seizures that could be elicited by alerting stimuli and were associated with ictal bilateral thalamic and right orbital-insular hyperperfusion on SPECT imaging. Case report. University Hospital Zurich. One patient with pharmaco-resistant epilepsy. This case shows that the arousal system plays a fundamental role also in cryptogenic non-familial forms of NFLE.

  12. Cylindrically symmetric cosmological model of the universe in modified gravity

    NASA Astrophysics Data System (ADS)

    Mishra, B.; Vadrevu, Samhita

    2017-02-01

    In this paper, we have constructed the cosmological models of the universe in a cylindrically symmetric space time in two classes of f(R,T) gravity (Harko et al. in Phys. Rev. D 84:024020, 2011). We have discussed two cases: one in the linear form and the other in the quadratic form of R. The matter is considered to be in the form of perfect fluid. It is observed that in the first case, the pressure and energy density remain the same, which reduces to a Zeldovich fluid. In the second case we have studied the quadratic function of f(R,T) gravity in the form f(R)=λ(R+R2) and f(T)=λ T. In the second case the pressure is in the negative domain and the energy density is in the positive domain, which confirms that the equation of state parameter is negative. The physical properties of the constructed models are studied.

  13. 20 CFR 10.211 - What are the employer's responsibilities in COP cases?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... responsibilities in COP cases? Once the employer learns of a traumatic injury sustained by an employee, it shall: (a) Provide a Form CA-1 and Form CA-16 to authorize medical care in accordance with § 10.300. Failure.../or terminate pay, and the basis for doing so. (d) Complete Form CA-1 and transmit it, along with all...

  14. 20 CFR 10.211 - What are the employer's responsibilities in COP cases?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... responsibilities in COP cases? Once the employer learns of a traumatic injury sustained by an employee, it shall: (a) Provide a Form CA-1 and Form CA-16 to authorize medical care in accordance with § 10.300. Failure.../or terminate pay, and the basis for doing so. (d) Complete Form CA-1 and transmit it, along with all...

  15. 20 CFR 10.211 - What are the employer's responsibilities in COP cases?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... responsibilities in COP cases? Once the employer learns of a traumatic injury sustained by an employee, it shall: (a) Provide a Form CA-1 and Form CA-16 to authorize medical care in accordance with § 10.300. Failure.../or terminate pay, and the basis for doing so. (d) Complete Form CA-1 and transmit it, along with all...

  16. 20 CFR 10.211 - What are the employer's responsibilities in COP cases?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... responsibilities in COP cases? Once the employer learns of a traumatic injury sustained by an employee, it shall: (a) Provide a Form CA-1 and Form CA-16 to authorize medical care in accordance with § 10.300. Failure.../or terminate pay, and the basis for doing so. (d) Complete Form CA-1 and transmit it, along with all...

  17. 20 CFR 10.211 - What are the employer's responsibilities in COP cases?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... responsibilities in COP cases? Once the employer learns of a traumatic injury sustained by an employee, it shall: (a) Provide a Form CA-1 and Form CA-16 to authorize medical care in accordance with § 10.300. Failure.../or terminate pay, and the basis for doing so. (d) Complete Form CA-1 and transmit it, along with all...

  18. Enhancing Technology Education by Forming Links with Industry: A New Zealand Case Study

    ERIC Educational Resources Information Center

    Brunton, Margaret; Coll, Richard K.

    2005-01-01

    The New Zealand technology curriculum suggests that schools should seek to develop links with industry as a means of providing real-world examples of technology practice. However, if a school is to form links, what form might such links take, and with whom should they be made? The case study research reported here represents an investigation into…

  19. On the Functional Neuroanatomy of Visual Word Processing: Effects of Case and Letter Deviance

    ERIC Educational Resources Information Center

    Kronbichler, Martin; Klackl, Johannes; Richlan, Fabio; Schurz, Matthias; Staffen, Wolfgang; Ladurner, Gunther; Wimmer, Heinz

    2009-01-01

    This functional magnetic resonance imaging study contrasted case-deviant and letter-deviant forms with familiar forms of the same phonological words (e.g., "TaXi" and "Taksi" vs. "Taxi") and found that both types of deviance led to increased activation in a left occipito-temporal region, corresponding to the visual word form area (VWFA). The…

  20. Congenital Neonatal Hyperthyroidism Caused by Germline Mutations in the TSH Receptor Gene: Case Report and Review of the Literature

    PubMed Central

    Chester, Jeremy; Rotenstein, Deborah; Ringkananont, Usanee; Steuer, Guy; Carlin, Beatrice; Stewart, Lindsay; Grasberger, Helmut; Refetoff, Samuel

    2018-01-01

    Neonatal hyperthyroidism, a rare and serious disorder occurs in two forms. An autoimmune form associated with maternal Graves’ disease, resulting from transplacental passage of maternal thyroid-stimulating antibodies, and a nonautoimmune form, resulting from mutations in the stimulatory G protein or the thyrotropin receptor (TSHR) causing constitutive activation of intracellular signaling cascades. To date, 29 separate cases of thyrotoxicosis caused by germline mutations of the TSHR have been documented. These cases have expressed themselves in a range of clinical consequences. This report describes a new case of a newborn with nonautoimmune hyperthyroidism secondary to a constitutively active TSHR mutation (S281N) whose clinical course was complicated by severe respiratory compromise. Typical clinical findings in this disorder are discussed by a review of all previously published cases. PMID:18655531

  1. Meteorological conditions during the formation of ice on aircraft

    NASA Technical Reports Server (NTRS)

    Samuels, L T

    1932-01-01

    These are the results of a number of records recently secured from autographic meteorological instruments mounted on airplanes at times when ice formed. Ice is found to collect on an airplane only when the airplane is in some form of visible moisture, such as cloud, fog, mist, rain. etc., and the air temperature is within certain critical limits. Described here are the characteristics of clear ice and rime ice and the specific types of hazards they present to airplanes and lighter than air vehicles. The weather records are classified according to the two general types of formation (clear ice and rime) together with the respective temperatures, relative humidities, clouds, and elevations above ground at which formations occurred. This classification includes 108 cases where rime formed, 43 cases in which clear ice formed, and 4 cases when both rime and clear ice formed during the same flight. It is evident from the above figures that there was a preponderance of rime by the ratio of 2.5 to 1, while in only a few cases both types of ice formation occurred during the same flight.

  2. Evaluation of a problem-specific SBAR tool to improve after-hours nurse-physician phone communication: a randomized trial.

    PubMed

    Joffe, Erel; Turley, James P; Hwang, Kevin O; Johnson, Todd R; Johnson, Craig W; Bernstam, Elmer V

    2013-11-01

    After-hours telephone communications are common in patient management. Patterns of communication of key information during after-hours phone calls were evaluated, and the utility of problem-specific Situation, Background, Assessment, Recommendation (SBAR) forms in improving this communication was assessed. In a randomized trial using a simulated on-call setting, 20 nurses called physicians regarding six cases adapted from inpatient records and based on the six most common reasons for after-hours nurse-physician communication. Three of the cases were handled without the SBAR forms (control cases), and three cases were handled with the forms (SBAR cases). Two cue types of communication were evaluated: situation cues, which conveyed the patient's situation (for example, a patient is confused), and background cues, which conveyed problem-specific data indicated on the SBAR forms (for example, the patient has a low sodium level). Ninety-two phone calls were analyzed (43 SBAR/49 controls). Most of the nurses reported the situation cues (SBAR 88%, control 84%, p = .60) but not the background cues. There was a trend toward fewer background cues communicated in the SBAR cases (14% versus 31%, p = .08). In 14% of the cases, on average, nurses omitted information or reported wrong information regarding the background cue. Physicians asked questions that resulted in the communication of the cues in a minority of the cases when the background cues were not originally provided by the nurses (SBAR 6%, control 16%, p = .39). In after-hours phone communication between physicians and nurses, significant information was often not communicated and physicians did not elicit the necessary information. Simply providing an SBAR-based form did not ensure complete communication of key information.

  3. TRANSFORMER

    DOEpatents

    Baker, W.R.

    1959-08-25

    Transformers of a type adapted for use with extreme high power vacuum tubes where current requirements may be of the order of 2,000 to 200,000 amperes are described. The transformer casing has the form of a re-entrant section being extended through an opening in one end of the cylinder to form a coaxial terminal arrangement. A toroidal multi-turn primary winding is disposed within the casing in coaxial relationship therein. In a second embodiment, means are provided for forming the casing as a multi-turn secondary. The transformer is characterized by minimized resistance heating, minimized external magnetic flux, and an economical construction.

  4. THE LIABILITY FORMS OF THE MEDICAL PERSONNEL.

    PubMed

    Bărcan, Cristian

    2015-01-01

    Current legislation, namely Law no. 95/2006 on healthcare reform in the medical malpractice domain stipulates that medical staff can be held accountable in the following forms: disciplinary liability, administrative liability, civil liability and criminal liability. Each form of legal liability presents its features, aspects that are found mainly in the procedural rules. However, the differences between the various legal forms of liability are not met only in the procedural rules but also in their effects and consequences. It is necessary to know what the procedure for disciplinary responsibility, administrative liability, civil liability, or criminal liability is. In addition to the differentiation determined by the consequences that may arise from the different forms of legal liability, it is important to know the competent authorities to investigate a case further and the solutions which various public institutions can take regarding the medical staff. Depending on the type of legal liability, authorities have a specialized authority. If the Disciplinary Committee is encountered at the College of Physicians, it may not intervene in cases before the monitoring and competence for malpractice cases Committee. The latter two committees cannot intervene directly in the legal assessment of civil or criminal cases, as no criminal investigation authorities cannot intervene in strictly civilian cases. Therefore, the importance of knowing the competent institutions is imperative.

  5. [Epidemiology of familial prostatic cancer: 4-year assessment of French studies].

    PubMed

    Valeri, A; Drelon, E; Azzouzi, R; Delannoy, A; Teillac, P; Fournier, G; Mangin, P; Berthon, P; Cussenot, O

    1999-09-01

    (1) To determine the frequency of familial (at least 2 cases) and hereditary forms of prostate cancer (CaP), (2) to define the results according to the patient's age at diagnosis, as various epidemiological studies have demonstrated a possible familial aggregation of CaP in about 15 to 25% of cases. Carter's familial segregation study (P.N.A.S. 1992, 89, 3367-71) showed that a genetic predisposition, with autosomal dominant transmission, could be responsible for 9% of all cases of prostate cancer. We conducted a systematic genealogy study of patients suffering from newly diagnosed CaP or followed for known CaP in 3 French urological centres, by means of questionnaires completed by the patients. Subsequently, a national collection of families with at least 2 cases of CaP identified families with hereditary forms of CaP. Hereditary cases were considered to be those presenting at least: one CaP in three 1st degree relatives, or 3 cases over 3 generations in the same branch of the family (paternal or maternal), or finally 2 early cases before the age of 55 years. Statistical analysis used the univariate logistic regression test between family status and the medical centre or the patient's age at diagnosis. From July 1994 onwards, we included 801 patients (all stages combined) in the systematic study and 110 patients (13.7%) were excluded (refusal to participate, advanced age). For 691 of the families studied (Brest: 225, Nancy: 249, Paris St Louis: 217), we observed 32 (14.2%), 29 (11.6%), 37 (17.1%) of familial forms (mean: 14.2%) and 11 (4.9%), 6 (2.4%), 8 (3.7%) of hereditary forms (mean: 3.6%), respectively (no significant differences between centres). Analysis of the results according to age at diagnosis of CaP also showed a higher incidence of familial (significant difference) and hereditary forms (limit of significance) for CaP occurring at a younger age (before 65 years). The national collection collected a total of 624 familial forms of CaP, including 236 (37.8%) cases of hereditary forms; 115 families were informative for the genetic linkage study. These results confirm the data of earlier studies, revealing about 15 to 25% of familial forms of CaP and 5 to 10% of hereditary forms. Similarly, the systematic study confirmed the earlier onset of CaP in patients with a genetic predisposition. These data therefore encourage systematic questioning of patients for a family history of CaP in order to propose targeted screening of high-risk subjects in the families concerned and to intensify identification of hereditary forms in order to investigate the genes involved.

  6. Mechanism of concave ``tafoni'' and convex ``domal shape'' formation on TRIASSIC red sandstone of some old buildings, Chester City, UK, Case study

    NASA Astrophysics Data System (ADS)

    Kamh, G. M. E.

    2005-08-01

    The weathering factors act on the recent and archaeological sites through different processes based on the dominant environmental conditions. The net result of weathering is deformation of the original form of construction rock. In the current case study, the main aim is to find out the mechanism of formation of two different weathering forms recorded on many old buildings taking Chester City as a case study. The construction rock in the case study is arenitic sandstone with carbonate content ranging from 0.0 to 15.6%. The sandstone blocks are cemented together by hydraulic lime mortar that can easily be altered chemically to salts by acid rain that dominates at the study area. In case of mortar with worse geotechnical limits than the sandstone blocks, the net result is convex “domal” shape blocks, but in case of mortar with better geotechnical limits than the construction sandstone, the net result of weathering is tafoni “concave” weathering form.

  7. Atypical P. vivax and P. ovale morphology in two imported cases of malaria in Spain.

    PubMed

    Vasallo Matilla, F; Perez Santos, M J; Ortega Moreno, E; Ortega Torres, M G; Diaz Molina, M; de Zulueta, J

    1997-03-01

    The finding of two imported cases of malaria in Spain is reported. Although their origin, their age and their clinical history were different, they both showed parasites of atypical morphology. One was diagnosed as P. vivax and the other as P. ovale, but the morphology observed in both cases does not correspond to what is considered as normal in the two species. In the first case forms similar to those of P. ovale were observed and in the second case P. vivax-like forms. The findings reported confirm the overlapping morphological variability of the two species.

  8. [Enviromental factors in the pathogenesis of thyroid cancer].

    PubMed

    Gubetta, L; Costa, A

    1978-07-14

    Local factors with a possible influence on the frequency and histological type of thyroid cancer are examined in the light of cases observed at the Mauriziano Hospital in the last 10 years. The overall number of cases has been increasing and papilliferous forms have been more common than follicular forms. Iodine deficiency and thyrotropin hyper-stimulation encourage onset and account for the higher frequency of thyroid cancer in endemic areas, where, however, follicular forms are more common. Ironising radiation is a direct cause, particularly of papilliferous forms arising after exposure during youth.

  9. Elastic field of a spherical inclusion with non-uniform eigenfields in second strain gradient elasticity

    NASA Astrophysics Data System (ADS)

    Delfani, M. R.; Latifi Shahandashti, M.

    2017-09-01

    In this paper, within the complete form of Mindlin's second strain gradient theory, the elastic field of an isolated spherical inclusion embedded in an infinitely extended homogeneous isotropic medium due to a non-uniform distribution of eigenfields is determined. These eigenfields, in addition to eigenstrain, comprise eigen double and eigen triple strains. After the derivation of a closed-form expression for Green's function associated with the problem, two different cases of non-uniform distribution of the eigenfields are considered as follows: (i) radial distribution, i.e. the distributions of the eigenfields are functions of only the radial distance of points from the centre of inclusion, and (ii) polynomial distribution, i.e. the distributions of the eigenfields are polynomial functions in the Cartesian coordinates of points. While the obtained solution for the elastic field of the latter case takes the form of an infinite series, the solution to the former case is represented in a closed form. Moreover, Eshelby's tensors associated with the two mentioned cases are obtained.

  10. The clinical spectrum of late-onset Alexander disease: a systematic literature review.

    PubMed

    Balbi, Pietro; Salvini, Silvana; Fundarò, Cira; Frazzitta, Giuseppe; Maestri, Roberto; Mosah, Dibo; Uggetti, Carla; Sechi, GianPietro

    2010-12-01

    Following the discovery of glial fibrillary acidic protein (GFAP) mutations as the causative factor of Alexander disease (AxD), new case reports have recently increased, prompting a more detailed comprehension of the clinical features of the three disease subtypes (infantile, juvenile and adult). While the clinical pattern of the infantile form has been substantially confirmed, the late-onset subtypes (i.e., juvenile and adult), once considered rare manifestations of AxD, have displayed a wider clinical spectrum. Our aim was to evaluate the clinical phenotype of the adult and juvenile forms by reviewing the previously reported cases. Data were collected from previously published reports on 112 subjects affected by neuropathologically or genetically proven adult and juvenile Alexander disease. Although the late-onset forms of AxD show a wide clinical variability, a common pattern emerges from comparing previously reported cases, characterized by pseudo-bulbar signs, ataxia, and spasticity, associated with atrophy of the medulla and upper cervical cord on neuroimaging. Late-onset AxD cases can no longer be considered as rare manifestations of the disease. The clinical pattern usually reflects the topographic localization of the lesions, with adult cases displaying a predominant infratentorial localization of the lesions. Juvenile cases show clinical and radiological features which are intermediate between adult and infantile forms.

  11. [Selection of occlusal scheme on masticatory function in denture wearers].

    PubMed

    Koide, Kaoru

    2004-12-01

    The characteristics of full balanced occlusion (FBO) and lingualized occlusion (LO), which are occlusions that make up removable dentures, were investigated from the standpoint of masticatory function, and an attempt was made to clarify criteria for selecting and configuring occlusions to suit individual cases. Since there have been few studies that have quantitatively compared FBO and LO from the aspect of masticatory function, we decided to organize and present the characteristics of both in this paper based on our findings from studies carried out in our department. We found that LO offered a higher ability of food crushing, showed higher masticatory performance in the case of hard foods, displayed faster as well as smoother masticatory movement, and showed chewing patterns that were closer to the chopper type compared with FBO. Moreover, subjective evaluation by subjects indicated that "it was easier to eat and the food tasted better" with the LO compared with the FBO in the case of general foods. Furthermore, a comparison of anatomical form and bladed form of upper lingual cusps in the case of LO showed no difference between the anatomical form and the bladed form in terms of masticatory performance in the case of any of the test foods, but the bladed form offered a higher ability of food crushing, displayed faster and smoother masticatory movement, and showed chewing patterns that were closer to the chopper type. In addition, subjective evaluation by subjects showed that it was easier for them to eat raw carrots and pickled radish, which are hard foods generally thought to be difficult to eat with dentures, with the bladed form compared with the anatomical form.

  12. Energy conversion device with improved seal

    DOEpatents

    Miller, Gerald R.; Virkar, Anil V.

    1980-01-01

    An energy conversion device comprising an improved sealing member adapted to seal a cation-permeable casing to the remainder of the device. The sealing member comprises a metal substrate which (i) bears a nonconductive and corrosion resistant coating on the major surface to which said casing is sealed, and (ii) is corrugated so as to render it flexible, thereby allowing said member to move relative to said casing without cracking the seal therebetween. Corrugations may be circumferential, radial, or both radial and circumferential so as to form dimples. The corrugated member may be in form of a bellows or in a substantially flat form, such as a disc.

  13. Surgical treatment and histopathology of different forms of olecranon and presternal bursitis in cattle and buffalo

    PubMed Central

    Fathy, Ahmed

    2006-01-01

    Thirty seven cases of bursitis presented to our Veterinary Teaching Hospital from 2001 to 2005. There were 10 adult female buffalos with olecranon bursitis (one had bilateral bursitis) and 26 calves (7 cattle and 19 buffalos, 16 males and 10 females) with presternal bursitis. There were 10 out of 11 cases of olecranon bursitis and 21 out of 26 cases of presternal bursitis with different forms (cystic, proliferative and fibrous) that were removed surgically. The remaining 6 cases, cystic bursitis (olecranon = 1, presternal = 5), were treated by aspiration of their contents and injection of 4% iodine tincture intrabursally. Only 2 cases recovered, 3 cases progressed to fibrosis and required further surgical treatment 2 to 3 weeks later, and 1 case continued to have a cystic lesion. Histopathological examination of tissue specimens from different forms of bursitis revealed that the acquired bursae were generally lined with synovial-like membrane formed from 2-3 cellular layers that covered the connective tissue capsule. The connective tissue capsule differed from one type to another and consisted of fibrous tissues containing numerous small blood vessels, blood capillaries, lymphatics and nerves. There was also evidence for inflammation within the capsule represented by congestion of blood vessels and the presence of perivascular inflammatory cells, mostly mononuclear. In conclusion, surgical treatment was successful and effective for treatment of olecranon and presternal bursitis particularly for the chronic proliferative and fibrous form in cattle and buffalo. The histological structure of the acquired bursae was relatively similar consisting of a synovial-like membrane and a connective tissue capsule with varying degrees of the inflammatory process. PMID:16871025

  14. Integration of a Zero-footprint Cloud-based Picture Archiving and Communication System with Customizable Forms for Radiology Research and Education.

    PubMed

    Hostetter, Jason; Khanna, Nishanth; Mandell, Jacob C

    2018-06-01

    The purpose of this study was to integrate web-based forms with a zero-footprint cloud-based Picture Archiving and Communication Systems (PACS) to create a tool of potential benefit to radiology research and education. Web-based forms were created with a front-end and back-end architecture utilizing common programming languages including Vue.js, Node.js and MongoDB, and integrated into an existing zero-footprint cloud-based PACS. The web-based forms application can be accessed in any modern internet browser on desktop or mobile devices and allows the creation of customizable forms consisting of a variety of questions types. Each form can be linked to an individual DICOM examination or a collection of DICOM examinations. Several uses are demonstrated through a series of case studies, including implementation of a research platform for multi-reader multi-case (MRMC) studies and other imaging research, and creation of an online Objective Structure Clinical Examination (OSCE) and an educational case file. Copyright © 2018 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.

  15. 75 FR 82406 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-30

    ... interstate forms. 45 CFR 303.7 also requires CSE IV-D agencies to transmit child support case information on standard interstate forms when referring cases to other States and Territories for processing. During the... instructions have been clarified by highlighting policy information that was included with the instructions so...

  16. 29 CFR 2200.206 - Disclosure of information.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... working days after a case is designated for Simplified Proceedings, the Secretary shall provide the employer, free of charge, copies of the narrative (Form OSHA 1-A) and the worksheet (Form OSHA 1-B), or their equivalents. (2) Within 30 calendar days after a case is designated for Simplified Proceedings...

  17. 7 CFR 1822.267 - Special conditions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Board of Directors or similar governing body using a form entitled, “((Rural Housing Site) Loan to... any provisions are not appropriate to a particular case, proposed substitute language should be... housing. In all cases the following language will be added under “other conditions” on Form FmHA or its...

  18. 8 CFR 204.3 - Orphan cases under section 101(b)(1)(F) of the Act (non-Convention cases).

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... advanced processing application (or the advanced processing application concurrently with the orphan... home study preparer and/or fingerprint check. Advanced processing application means Form I-600A (Application for Advanced Processing of Orphan Petition) completed in accordance with the form's instructions...

  19. 8 CFR 204.3 - Orphan cases under section 101(b)(1)(F) of the Act (non-Convention cases).

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... advanced processing application (or the advanced processing application concurrently with the orphan... home study preparer and/or fingerprint check. Advanced processing application means Form I-600A (Application for Advanced Processing of Orphan Petition) completed in accordance with the form's instructions...

  20. 8 CFR 204.3 - Orphan cases under section 101(b)(1)(F) of the Act (non-Convention cases).

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... advanced processing application (or the advanced processing application concurrently with the orphan... home study preparer and/or fingerprint check. Advanced processing application means Form I-600A (Application for Advanced Processing of Orphan Petition) completed in accordance with the form's instructions...

  1. 8 CFR 204.3 - Orphan cases under section 101(b)(1)(F) of the Act (non-Convention cases).

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... advanced processing application (or the advanced processing application concurrently with the orphan... home study preparer and/or fingerprint check. Advanced processing application means Form I-600A (Application for Advanced Processing of Orphan Petition) completed in accordance with the form's instructions...

  2. 8 CFR 204.3 - Orphan cases under section 101(b)(1)(F) of the Act (non-Convention cases).

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... advanced processing application (or the advanced processing application concurrently with the orphan... home study preparer and/or fingerprint check. Advanced processing application means Form I-600A (Application for Advanced Processing of Orphan Petition) completed in accordance with the form's instructions...

  3. 7 CFR 1822.267 - Special conditions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Board of Directors or similar governing body using a form entitled, “((Rural Housing Site) Loan to... any provisions are not appropriate to a particular case, proposed substitute language should be... housing. In all cases the following language will be added under “other conditions” on Form FmHA or its...

  4. 7 CFR 1822.267 - Special conditions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Board of Directors or similar governing body using a form entitled, “((Rural Housing Site) Loan to... any provisions are not appropriate to a particular case, proposed substitute language should be... housing. In all cases the following language will be added under “other conditions” on Form FmHA or its...

  5. 77 FR 39709 - Proposed Information Collection Activity; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-05

    ... Individual Case Management Report and Financial Claim Form: Under Section 1113 of the Social Security Act... or more. Individual Case Management Report and Financial Claim Form: Estimated Total Annual Burden... U.S. because of destitution, illness, war, threat of war, or a similar crisis, and are without...

  6. SEGMENTAL NEUROFIBROMATOSIS: A REPORT OF 3 CASES

    PubMed Central

    Gabhane, Sushma Kashinath; Kotwal, Mrunmayi Nishikant; Bobhate, Sudhakar K

    2010-01-01

    Neurofibromatosis is a genetic disorder of neural crest-derived cells that primarily affect growth of neural tissues. It is broadly divided into three categories: (a) von Recklinghausen's neurofibromatosis or NF-1, (b) bilateral acoustic neuroma (NF-2), and (c) all other neurofibromatoses, including alternate or atypical forms of the disease. The patients with generalized form of NF1 are characterized by multiple café-au-lait spots and neurofibromas and diagnosed easily. But when an individual has small number of lesions in a limited region of the body it could be neglected by the patient or not be recognized by the clinicians as a segmental form of neurofibromatosis. We describe three cases of segmental neurofibromatosis (SNF). These cases have been classified as segmental NF according to Riccardi's definition of SNF and classification of neurofibromatosis. Segmental form of NF may evolve into a complete form over time. Also, this disorder may be transmitted to the offspring's of these individuals. Hence genetic counseling of these individuals must include these facts. PMID:20418991

  7. Pleural mesothelioma – case report

    PubMed Central

    Klawiter, Anna; Damaszke, Tomasz

    2010-01-01

    Summary Background: Pleural mesothelioma is a very rare neoplasm; especially the local form. The diagnostics is difficult and the prognosis unfavourable. Case Report: We presented a case of a man with dyspnoea and cough. His chest radiogram showed hydrothorax on the left side. Neither the examinations of the pleural liquid, nor the CT-guided fine needle biopsy established the diagnosis. CT showed features suggestive of pleural mesothelioma. The diagnosis was confirmed by thoracoscopy. Although no neoplastic cells were found in the thoracoscopic specimen from the supradiaphragmatic tumor, we assumed that to be a case of a diffuse, primarily local form of mesothelioma. Conclusions: Diagnostics of pleural mesothelioma is very difficult. CT and thoracoscopy seem to be very valuable diagnostic methods. It is worth remembering that pleural mesothelioma can have a local form which may transform into a diffuse one. PMID:22802809

  8. Using ITS to Create an Insurance Industry Application: A Joint Case Study.

    ERIC Educational Resources Information Center

    Boies, Stephen J.; And Others

    1993-01-01

    Presents an empirical case study of the use of ITS, a software development environment designed by IBM, by Continental Insurance for underwriting applications. Use of a rule-based user interface style that made electronic forms look like standard insurance industry paper forms and worked according to Continental's guidelines is described.…

  9. 77 FR 26511 - Announcing a National Cybersecurity Center of Excellence (NCCoE) Workshop

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-04

    ... possible case studies that are expected to form a central focus of collaborative efforts. The workshop will... possible case studies that are expected to form a central focus of collaborative efforts. The workshop will... together experts from industry, government and academia under one roof to develop practical, interoperable...

  10. [Epidermolysis bullosa in peru: clinical and epidemiological study of patients treated in a national reference pediatric hospital, 1993-2015].

    PubMed

    Torres-Iberico, Rosario; Palomo-Luck, Patricia; Torres-Ramos, Gilmer; Lipa-Chancolla, Roxana

    2017-01-01

    To describe the clinical and epidemiological characteristics of patients diagnosed with epidermolysis bullosa (EB) at the Instituto Nacional de Salud (INSN) in Lima, Peru; a National Reference Center for this disease. Observational, descriptive and transversal study. We reviewed the clinical histories and laboratory tests of patients diagnosed with EB treated in INSN from 1993 to 2015. 93 patients were registered. The average age was 7.9 ± 5.6 years; 53.8% (n = 50) were boys. Clinical forms corresponded to dystrophic EB with 41 (44.1%) cases, simple EB with 39 (41.9%), union EB cases with 8 (8.6%) and Kindler syndrome with 4 (4.3%) cases. The clinical form could not be identified in a case. A total of 48 cases (51.6%) came from Lima and Callao, and 45 cases (48.4%) from other provinces of the country. Extracutaneous manifestations involved gastrointestinal (44.1%), ocular (37.6%), odontogenic (87.1%), and nutritional (79.6%) involvement, as well as pseudosindactilia (16.1%). Chronic malnutrition (71.6%), acute malnutrition (17.6%) and anemia (62.4%) were found. Mortality corresponded to 6 cases (6.5%). 93 cases of EB were reported in INSN, the predominant clinical presentation was the dystrophic form.

  11. Renormalization group, normal form theory and the Ising model

    NASA Astrophysics Data System (ADS)

    Raju, Archishman; Hayden, Lorien; Clement, Colin; Liarte, Danilo; Sethna, James

    The results of the renormalization group are commonly advertised as the existence of power law singularities at critical points. Logarithmic and exponential corrections are seen as special cases and dealt with on a case-by-case basis. We propose to systematize computing the singularities in the renormalization group using perturbative normal form theory. This gives us a way to classify all such singularities in a unified framework and to generate a systematic machinery to do scaling collapses. We show that this procedure leads to some new results even in classic cases like the Ising model and has general applicability.

  12. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Falk, H.; Herbert, J.T.; Edmonds, L.

    Four cases of childhood hepatic angiosarcoma (HAS), representing the malignant form of infantile hemangioendothelioma, are described. The morphologic appearance of childhood HAS differs from the adult form in the following features: the associated presence of benign infantile hemagioendothelioma; the presence of dysontogenetic features; and an altered appearance of the angiosarcoma itself. It is postulated for these cases that the benigh infantile hemangioendothelioma progressed to the malignant angiosarcoma. One of the four cases had exposure to elevated levels of arsenic in the environment that may have contributed to this progression. This latter case adds to published reports associating arsenic exposure withmore » increased risk for hepatic angiosarcoma.« less

  13. The Diffuse Gamma-Ray Background from Type Ia Supernovae

    NASA Technical Reports Server (NTRS)

    Lien, Amy; Fields, Brian D.

    2012-01-01

    The origin of the diffuse extragalactic gamma-ray background (EGB) has been intensively studied but remains unsettled. Current popular source candidates include unresolved star-forming galaxies, starburst galaxies, and blazars. In this paper we calculate the EGB contribution from the interactions of cosmic rays accelerated by Type Ia supernovae, extending earlier work which only included core-collapse supernovae. We consider Type Ia events in star-forming galaxies, but also in quiescent galaxies that lack star formation. In the case of star-forming galaxies, consistently including Type Ia events makes little change to the star-forming EGB prediction, so long as both supernova types have the same cosmic-ray acceleration efficiencies in star-forming galaxies. Thus our updated EGB estimate continues to show that star-forming galaxies can represent a substantial portion of the signal measured by Fermi. In the case of quiescent galaxies, conversely, we find a wide range of possibilities for the EGB contribution. The dominant uncertainty we investigated comes from the mass in hot gas in these objects, which provides targets for cosmic rays: total gas masses are as yet poorly known, particularly at larger radii. Additionally, the EGB estimation is very sensitive to the cosmic-ray acceleration efficiency and confinement, especially in quiescent galaxies. In the most optimistic allowed scenarios, quiescent galaxies can be an important source of the EGB. In this case, star-forming galaxies and quiescent galaxies together will dominate the EGB and leave little room for other contributions. If other sources, such as blazars, are found to have important contributions to the EGB, then either the gas mass or cosmic-ray content of quiescent galaxies must be significantly lower than in their star-forming counterparts. In any case, improved Fermi EGB measurements will provide important constraints on hot gas and cosmic rays in quiescent galaxies.

  14. A rare case of isolated macronodular hepatic tuberculosis (Tuberculous) in an immunocompetent patient.

    PubMed

    Kayar, Yusuf; Ekinci, Iskender; Turkdogan, Figen Tunali; Atay, Musa; Soytas, Rabia Bag; Kayar, Nuket Bayram

    2015-11-01

    Tuberculosis is one of the most common and well described infectious diseases, with a world wide distribution and a vast spectrum of clinical manifestations. There are three forms of hepatic tuberculosis. Diffuse hepatic involvement with pulmonary or miliary tuberculosis, diffuse hepatic infiltration without recognizable pulmonary involvement is the second form and the third very rare form presents as a focal/local tuberculoma or abscess. In this case report we describe an unusual appearance of macronodular tuberculomas of the liver.

  15. The explicit form of the rate function for semi-Markov processes and its contractions

    NASA Astrophysics Data System (ADS)

    Sughiyama, Yuki; Kobayashi, Testuya J.

    2018-03-01

    We derive the explicit form of the rate function for semi-Markov processes. Here, the ‘random time change trick’ plays an essential role. Also, by exploiting the contraction principle of large deviation theory to the explicit form, we show that the fluctuation theorem (Gallavotti-Cohen symmetry) holds for semi-Markov cases. Furthermore, we elucidate that our rate function is an extension of the level 2.5 rate function for Markov processes to semi-Markov cases.

  16. The DISAM Journal of International Security Assistance Management. Volume 30, Number 1, March 2008

    DTIC Science & Technology

    2008-03-01

    annexation of a little patch of ground called Sudetenland? Or a French defeat at a place called Dien Bien Phu? Or the return of an obscure cleric to...chats on personal, non-work related subjects – including politics and religion. Family (children), sports, travel, and cuisine are safe...lieu of 2 standard forms can be approved on a case-by- forms or translated versions (Spanish, case basis. The request and forms French , etc.) need

  17. Two-point derivative dispersion relations

    NASA Astrophysics Data System (ADS)

    Ferreira, Erasmo; Sesma, Javier

    2013-03-01

    A new derivation is given for the representation, under certain conditions, of the integral dispersion relations of scattering theory through local forms. The resulting expressions have been obtained through an independent procedure to construct the real part and consist of new mathematical structures of double infinite summations of derivatives. In this new form the derivatives are calculated at the generic value of the energy E and separately at the reference point E = m that is the lower limit of the integration. This new form may be more interesting in certain circumstances and directly shows the origin of the difficulties in convergence that were present in the old truncated forms called standard-derivative dispersion relations (DDR). For all cases in which the reductions of the double to single sums were obtained in our previous work, leading to explicit demonstration of convergence, these new expressions are seen to be identical to the previous ones. We present, as a glossary, the most simplified explicit results for the DDR's in the cases of imaginary amplitudes of forms (E/m)λ[ln (E/m)]n that cover the cases of practical interest in particle physics phenomenology at high energies. We explicitly study the expressions for the cases with λ negative odd integers, that require identification of cancelation of singularities, and provide the corresponding final results.

  18. [Hemorrhagic rectocolitis or ulcerative colitis in the black Senegalese. Apropos of 14 cases].

    PubMed

    Aubry, P; Klotz, F; Oddes, B; Seurat, P L

    1984-01-01

    Ulcerative colitis is exceptional in Africa South of the Sahara. The first case was described in 1964: up to 1982, 46 cases were reported. We report on 14 cases (6 females and 8 males) observed in black Senegalese for three years and a half. The medium age of patients was 30 years. All of them had a high social standard of living. Four patients showed intestinal amebiasis in their previous medical history. Clinical and evolutive patterns of ulcerative colitis in Africa present few differences in comparison with the classical ones. The diagnosis is established by endoscopy (rectosigmoidoscopy and/or colonoscopy) and histopathology. Cryptic abscesses were found in only 2 out of 14 cases. Rectal dysplasia was noted in 2 cases. The course of the disease developed on a fulminating acute mode in one case, on a continuous chronic mode in another case and on a chronic mode with relapses in 11 cases. Irrespective to the clinical form observed, intestinal amebiasis represents the most pressing differential diagnosis. Treatment appears to be difficult in severe acute forms out of an intensive care department, as well as in advanced extensive chronic forms. For the later in black Africa endoscopic and histopathological surveillance appears to be preferable to a total colectomy, made necessary by the important rectal lesions, because the functional sequelae of an ileostomy.

  19. [Cutaneous tuberculosis in Bamako, Mali].

    PubMed

    Dicko, Adama; Faye, Ousmane; Fofana, Youssouf; Soumoutera, Moussa; Berthé, Siritio; Touré, Saidou; Traoré, Bekaye; Guindo, Binta; Tall, Koureissi; Keita, Alimata; Kéita, Lassine; Coulibaly, Karim; Keita, Somita

    2017-01-01

    Tuberculosis is the most common mycobacteriosis in sub-Saharan Africa. Cutaneous tuberculosis is rare and underdiagnosed due to its clinical polymorphism and to the smallness of technical equipment. This study aims to describe the epidemiological, clinical, histopathological aspects of cutaneous tuberculosis in Bamako (Mali). We conducted a cross-sectional descriptive study from January 1991 to December 2008. The study was performed in the Department of Dermatology at the National Center for Disease Control and in the Department of Pneumophtisiology at the Hospital of Point G. The patients with tuberculosis confirmed by histological and/or biological examination were included in the study. Out of 4269 patients? medical records, 61 cases of cutaneous tuberculosis were identified (1.43%). Men accounted for 59% of the cases (36 patients) and women 41% (25 cases); sex-ratio was 1.44. The age of the patients ranged from 3 months to 61 years, with an average age of 27.56 ± 36 years. The average length of follow-up was 10.9 ± 10 months. The identified clinical forms were scrofuloderma (41 cases), ulcerative form (13 cases), verrucous form (4 cases), and tuberculous Lupus (3 cases). Tuberculosis was associated with HIV in 7 cases, with leprosy in 3 cases. Cutaneous tuberculosis is underdiagnosed in Mali. Efforts are needed to improve the accessibility and the technical equipment available in the Departments, in order to conduct an extensive interdisciplinary study on this pathology.

  20. Reliability of Diagnostic Criteria for Neurocysticercosis for Patients with Ventricular Cystic Lesions or Granulomas: A systematic review.

    PubMed

    Bustos, Javier A; García, Hector H; Del Brutto, Oscar H

    2017-09-01

    Intraventricular neurocysticercosis (NCC) is a severe form of NCC requiring prompt diagnosis and treatment. We aimed to assess the reliability of the most recent version of diagnostic criteria for this form of NCC. Two systematic literature reviews were performed; one included case reports of patients with intraventricular cysticercosis and the other included case reports of patients with intraventricular cystic lesions or granulomas caused by infections other than NCC. All assessed cases were categorized according to the last revision of the long-standing Del Brutto's set of diagnostic criteria to determine its sensitivity, specificity, and predictive value for this form of NCC. The search disclosed 128 patients with intraventricular NCC and 41 with other infections. The set of diagnostic criteria classified as definitive NCC 93 cases with intraventricular NCC (sensitivity 72.7%, 95% CI, 63.9-79.9%), as well as four cases with other infections (specificity 90.2%, 95% CI, 75.9-96.8%). The positive and negative predictive values of the criteria were 0.96 (95% CI, 0.89-0.99) and 0.51 (95% CI, 0.39-0.63), respectively. The revised Del Brutto's set of diagnostic criteria for NCC is acceptably sensitive and highly specific for diagnosing patients with the ventricular form of the disease.

  1. Unilateral retinitis pigmentosa and cone-rod dystrophy

    PubMed Central

    Farrell, Donald F

    2009-01-01

    Purpose: The purpose of this paper is to report 14 new cases of unilateral retinitis pigmentosa and three new cases of cone-rod dystrophy and to compare the similarities and dissimilarities to those found in the bilateral forms of these disorders. Methods: A total of 272 cases of retinitis pigmentosa and 167 cases of cone-rod dystrophy were studied by corneal full field electroretinograms and electrooculograms. The student t-test was used to compare categories. Results: The percentage of familial and nonfamilial cases was the same for the bilateral and unilateral forms of the disease. In our series, unilateral retinitis pigmentosa makes up approximately 5% of the total population of retinitis pigmentosa, while unilateral cone-rod dystrophy makes up only about 2% of the total. In the familial forms of unilateral retinitis pigmentosa the most common inheritance pattern was autosomal dominant and all affected relatives had bilateral disease. Conclusion: Unilateral retinitis pigmentosa and cone-rod dystrophy appear to be directly related to the more common bilateral forms of these disorders. The genetic mechanisms which account for asymmetric disorders are not currently understood. It may be a different unidentified mutation at a single loci or it is possible that nonlinked mutations in multiple loci account for this unusual disorder. PMID:19668577

  2. Malignant fat-forming solitary fibrous tumor (so-called "lipomatous hemangiopericytoma"): clinicopathologic analysis of 14 cases.

    PubMed

    Lee, Jen-Chieh; Fletcher, Christopher D M

    2011-08-01

    Fat-forming solitary fibrous tumor is a rare variant of solitary fibrous tumor (SFT). Generally regarded as benign, very few fat-forming SFTs with malignant histologic features have been reported. Here, we report 14 histologically malignant fat-forming SFTs to better characterize this subset. Seven patients were female and 7 were male, with ages ranging 20 to 93 years (median, 57 y). Five tumors were located in the lower limb, 3 in the trunk, 3 in abdominopelvic locations, 2 in the head and neck region, and 1 in the upper limb. The tumor size ranged from 3.4 to 20 cm (median, 8.6 cm). Histologically, all exhibited at least focal hypercellularity; 12 tumors had mitoses >4/10 high-power fields (range, 2 to 37; median, 8), 12 showed at least moderate atypia, and 8 showed necrosis. It should be noted that 7 tumors contained only mature adipose tissue, whereas 5 contained multivacuolated lipoblasts and 2 had areas resembling atypical lipomatous tumor (ALT). Immunohistochemically, CD34 and CD99 were positive in most cases (11 of 14 and 8 of 10, respectively); MDM2 and CDK4 were both negative in all 4 cases tested (including both tumors with ALT-like areas). Follow-up data from 10 cases (median duration, 47.5 mo; range, 5 to 76) showed 2 patients with multiple metastases (both to lung and bones, and 1 each to breast and to soft tissue), both of whom died of disease. In conclusion, fat-forming SFTs exhibiting malignant histologic features have potential for aggressive behavior. The presence of lipoblasts and/or ALT-like areas, although described in some "benign" examples of fat-forming SFT, seems much more common in the malignant subset and may prompt a careful search for morphologic evidence of malignancy in any case of fat-forming SFT.

  3. 78 FR 56873 - Information Collection Being Reviewed by the Federal Communications Commission Under Delegated...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-16

    ... base stations that utilize multilateration technology to provide multilateration location service to....: 3060-0221. Title: Section 90.155, Time in Which Station Must Be Placed in Operation. Form No.: FCC Form... government entities to place their stations in operation on a case-by-case basis upon a showing of need. This...

  4. Applying Corpus-Based Findings to Form-Focused Instruction: The Case of Reported Speech

    ERIC Educational Resources Information Center

    Barbieri, Federica; Eckhardt, Suzanne E. B.

    2007-01-01

    Arguing that the introduction of corpus linguistics in teaching materials and the language classroom should be informed by theories and principles of SLA, this paper presents a case study illustrating how corpus-based findings on reported speech can be integrated into a form-focused model of instruction. After overviewing previous work which…

  5. Lasting Connections: A Case Study of Relationships Formed during a First-Year Seminar Course

    ERIC Educational Resources Information Center

    Enke, Kathryn A. E.

    2011-01-01

    This article investigates the evolution of friendships formed during a first-year seminar for honors students enrolled in a private liberal arts college. Through an electronic survey and interviews with former students who had participated in the seminar course six years prior to the research, this case study examined why some friendships were…

  6. 76 FR 82313 - Intent To Request Renewal From OMB of One Current Public Collection of Information...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-30

    ... Security Officer (TSO) to ensure their qualifications to perform TSO duties pursuant to 49 U.S.C 44965. In certain cases, TSO candidates' health care providers may be asked to complete supplemental forms. DATES... candidates and, in certain cases, supplemental forms completed by TSO candidates' health care providers. The...

  7. Visual Reasoning in Computational Environment: A Case of Graph Sketching

    ERIC Educational Resources Information Center

    Leung, Allen; Chan, King Wah

    2004-01-01

    This paper reports the case of a form six (grade 12) Hong Kong student's exploration of graph sketching in a computational environment. In particular, the student summarized his discovery in the form of two empirical laws. The student was interviewed and the interviewed data were used to map out a possible path of his visual reasoning. Critical…

  8. 17 CFR 229.601 - (Item 601) Exhibits.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... administered by the Commission. 2. In any case where two or more indentures, contracts, franchises, or other... computation of ratios X X X X X X X X (13) Annual report to security holders, Form 10-Q or quarterly report to... prospectus as permitted by the registration statement; or, in the case of the Form 10-K, where the annual...

  9. 17 CFR 229.601 - (Item 601) Exhibits.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... administered by the Commission. 2. In any case where two or more indentures, contracts, franchises, or other... computation of ratios X X X X X X X X (13) Annual report to security holders, Form 10-Q or quarterly report to... prospectus as permitted by the registration statement; or, in the case of the Form 10-K, where the annual...

  10. 17 CFR 229.601 - (Item 601) Exhibits.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... administered by the Commission. 2. In any case where two or more indentures, contracts, franchises, or other... computation of ratios X X X X X X X X (13) Annual report to security holders, Form 10-Q or quarterly report to... prospectus as permitted by the registration statement; or, in the case of the Form 10-K, where the annual...

  11. Janiceps conjoined twins with extreme asymmetry: case report with complete autopsy and histopathologic findings.

    PubMed

    Kastenbaum, Hannah A; McPherson, Elizabeth W; Murdoch, Geoffrey H; Ozolek, John A

    2009-01-01

    Conjoined twinning is a rare form of twinning, in which 2 bodies are attached, and is classified according to the anatomic place of attachment. An extremely rare form of conjoined twinning is janiceps conjoined twinning, in which 2 faces are attached but oriented in opposite directions. In this report, we present an unusual and difficult-to-classify case of conjoined male twins with partial duplication of craniofacial, upper oropharyngeal, and cardiac organs. We believe this to be one of the few reported cases of janiceps asymmetrus. We describe in detail the gross and microscopic pathology and offer some insights into the possible embryogenesis and distinction from the other rare form of conjoined twinning with facial duplication, diprosopus.

  12. The Role of Lattice Matching Techniques in the Characterization of Polymorphic Forms.

    PubMed

    Mighell, Alan D

    2011-01-01

    An inspection of the recent literature reveals that polymorphism is a frequently encountered phenomenon. The recognition of polymorphic forms plays a vital role in the materials sciences because such structures are characterized by different crystal packing and accordingly have different physical properties. In the pharmaceutical industry, recognition of polymorphic forms can be critical for, in certain cases, a polymorphic form of a drug may be an ineffective therapeutic agent due to its unfavorable physical properties. A check of the recent literature has revealed that in some cases new polymorphic forms are not recognized. In other instances, a supposedly new polymeric form is actually the result of an incorrect structure determination. Fortunately, lattice-matching techniques, which have proved invaluable in the identification and characterization of crystal structures, represent a powerful tool for analyzing polymorphic forms. These lattice-matching methods are based on either of two strategies: (a) the reduced cell strategy-the matching of reduced cells of the respective lattices or (b) the matrix strategy-the determination of a matrix or matrices relating the two lattices coupled with an analysis of the matrix elements. Herein, these techniques are applied to three typical cases-(a) the identification of a new polymorphic form, (b) the demonstration that a substance may not be a new polymorphic form due to missed symmetry, and (c) the evaluation of pseudo polymorphism because of a missed lattice. To identify new polymorphic forms and to prevent errors, it is recommended that these lattice matching techniques become an integral part of the editorial review process of crystallography journals.

  13. Grindability of alpha-case formed on cast titanium.

    PubMed

    Koike, Marie; Jacobson, David; Chan, Kwai S; Okabe, Toru

    2009-09-01

    The hardened alpha-case (alpha-case) layer inevitably forms on the surface of titanium castings when prepared by investment casting. Because the hardness of the alpha-case is incomparable to that of the interior structure, the perception exists that the alpha-case is difficult to remove during cutting, grinding and polishing. Grindability (ease of grinding) of cast cpTi and cast Ti-6Al-4V was evaluated by grinding cast specimens incrementally using a SiC abrasive wheel. The present study revealed that the presence of the brittle alpha-case with lower fracture toughness is beneficial in grinding titanium. The alpha-case on the ductile cpTi can be ground much easier than its bulk interior structure. In less ductile Ti-6Al-4V, the grinding rate is much higher than that of cpTi, and the alpha-case and its interior structure are at similar levels since the fracture toughness of its alpha-case and the bulk material is not large enough.

  14. 48 CFR 1913.505-2 - Board order forms in lieu of Optional and Standard Forms.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... BROADCASTING BOARD OF GOVERNORS CONTRACTING METHODS AND CONTRACT TYPES SMALL PURCHASES AND OTHER SIMPLIFIED...-case basis, in order to accommodate computer-generated purchase order forms. Exception approval for...

  15. 48 CFR 1913.505-2 - Board order forms in lieu of Optional and Standard Forms.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... BROADCASTING BOARD OF GOVERNORS CONTRACTING METHODS AND CONTRACT TYPES SMALL PURCHASES AND OTHER SIMPLIFIED...-case basis, in order to accommodate computer-generated purchase order forms. Exception approval for...

  16. Commutative semigroups of real and complex matrices. [with use of the jordan form

    NASA Technical Reports Server (NTRS)

    Brown, D. R.

    1974-01-01

    The computation of divergence is studied. Covariance matrices to be analyzed admit a common diagonalization, or even triangulation. Sufficient conditions are given for such phenomena to take place, the arguments cover both real and complex matrices, and are not restricted to Hermotian or other special forms. Specifically, it is shown to be sufficient that the matrices in question commute in order to admit a common triangulation. Several results hold in the case that the matrices in question form a closed and bounded set, rather than only in the finite case.

  17. 'Munchausen syndrome by proxy' presenting as battered child syndrome: a report of two cases.

    PubMed

    Sugandhan, Selvendran; Gupta, Somesh; Khandpur, Sujay; Khanna, Neena; Mehta, Manju; Inna, Prashanth

    2010-06-01

    Child abuse is a major public health crisis and is on the rise. Dermatologists are frequently involved in its evaluation in differentiating abusive injuries from accidental injuries and in excluding pathological conditions that may mimic abuse. Battered child syndrome or physical abuse is not only a common form of child abuse but can also result from a rarer form of child abuse known as Munchausen syndrome by proxy. In this form of abuse, mother, who is the usual perpetrator, induces an illness or abuses the child for her own self-serving psychological needs. We report two cases of battered child syndrome. In both the cases, Psychiatric evaluation was performed on both parents. Observation through one-way mirror was done with the mother and the child alone. Routine hematological and biochemical investigations were done. Diagnosis of Munchausen syndrome by proxy was firmly established in one case and was considered as a possibility in the other. A multidisciplinary team effort is essential in evaluating such cases, and dermatologists should be aware and be well informed about this condition that can be potentially lethal but easily overlooked.

  18. History repeating itself: Arnaud's case of pathological déjà vu.

    PubMed

    Bertrand, Julie M F; Martinon, Léa M; Souchay, Céline; Moulin, Chris J A

    2017-02-01

    We present a translation of Arnaud's (1896) case report of Patient Louis, a case he describes as having a pathological form of déjà vu. Louis has the delusional belief that the present moment is a repetition of an exact same previous event. Arnaud's paper is critical for two reasons. Firstly, it is amongst the first articles in the scientific literature to describe the déjà vu experience using the term 'déjà vu'. Secondly, the case report of someone with delusional and persistent déjà vu, anticipates recently reported cases with similar symptoms, which are beginning to gain interest as a particular form of memory disorder. We offer a contemporary analysis of Louis and conclude that, whilst the article was critical in the development of déjà vu as a scientific concern, Louis's distorted memory is not best described as déjà vu, but rather as a form of reduplicative paramnesia described as recollective confabulation. Copyright © 2016 Elsevier Ltd. All rights reserved.

  19. Nature and Role of Traditional Forms of Counselling in Zambia: A Case of Lusaka Province

    ERIC Educational Resources Information Center

    Chiboola, Hector; Munsaka, Sody M.

    2018-01-01

    The aim of this study was to determine the nature and role of traditional forms of counselling and the scope of common problems presented to traditional counsellors in Lusaka province. It used a qualitative research methodology and deployed a holistic single-case study design with multiple embedded units of analysis. The sample consisted of 80…

  20. Macrodystrophia lipomatosa. A case report.

    PubMed

    Loro, A; Francechi, F; Dal Lago, A

    1995-07-01

    Macrodystrophia lipomatosa, a rare form of localized gigantism of unknown cause, is characterized by a dramatic overgrowth of all the mesenchymal elements, particularly the fibroadipose tissue, of one or more digits of the foot or hand. Of the known forms, static and progressive (1), we report the case of an African patient, of Bantu origin, who had a progressive deformity of his left hand.

  1. Socio-Psychological Aspects of Animal Therapy in Treating Children Suffering from Forms of Dysontogenesis

    ERIC Educational Resources Information Center

    Nikolskaya, Anastasia V.

    2012-01-01

    Positive and negative aspects of animal therapy using are discussed. Research of 30 case studies is displayed that pet therapy is a good therapeutic tool in approximately 60% of cases. To diagnose possible problems in families which have got a dog as a "therapist" for the child suffering from some or other form of dysontogenesis, the…

  2. Deaths among women of reproductive age: a forensic autopsy study.

    PubMed

    Padubidri, Jagadish Rao; Menezes, Ritesh G; Pant, Sadip; Shetty, Soumya B

    2013-08-01

    Unnatural deaths in women of reproductive age (range 12-49 years) have a serious psychological and social impact on the family and community. Deaths among women of reproductive age reported as medico-legal cases were investigated to see the trend in terms of cause and manner of death. The study group consisted of a series of 328 consecutive forensic autopsies on women in the reproductive age group, performed between 2009 and 2011 at the Government Wenlock District Hospital, Mangalore, India by qualified specialist forensic medicine experts. Unnatural deaths formed 93.6% of the cohort. The top three causes of death included burns, poisoning and hanging forming 69.5% of the cases. The manner of death was suicide in 45.4% cases, accident in 43.6% cases and homicide in 4.6% cases. The circumstances of death were related to alleged medical negligence in 2.4% cases. Death in 4% cases was natural mannered with a disease being the cause of death. Three-fourths of the victims were married. Married women formed 63.1% of the suicidal victims. Homicidal deaths were not reported among unmarried women. The preponderant method of suicide was by poisoning at 42.3% (63 cases), followed by hanging (34.9%), burns (11.4%) and drowning (9.4%). These four methods comprised 98% of the total suicidal deaths in this study cohort. Accidental deaths were predominantly caused by burns (62.2%) and road traffic accident (23.1%). Two-thirds of the homicidal deaths were due to assault caused by blunt-force trauma, ligature strangulation and sharp-force trauma. One-third of the homicidal victims died due to burns. With a clear understanding of the cause and manner of death, it may be possible to predict, and hopefully prevent, future cases of unnatural deaths in women of reproductive age who form a very important group of society. Copyright © 2013 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.

  3. 75 FR 10022 - Proposed Collection; Comment Request For Form 4804

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-04

    ... file reports of this income with the IRS. In certain cases, this information must be filed on magnetic media. Form 4804 is a transmittal form for the magnetic media, which indicates the payer, type of...

  4. Algebraic Bethe ansatz for the XXZ Heisenberg spin chain with triangular boundaries and the corresponding Gaudin model

    NASA Astrophysics Data System (ADS)

    Manojlović, N.; Salom, I.

    2017-10-01

    The implementation of the algebraic Bethe ansatz for the XXZ Heisenberg spin chain in the case, when both reflection matrices have the upper-triangular form is analyzed. The general form of the Bethe vectors is studied. In the particular form, Bethe vectors admit the recurrent procedure, with an appropriate modification, used previously in the case of the XXX Heisenberg chain. As expected, these Bethe vectors yield the strikingly simple expression for the off-shell action of the transfer matrix of the chain as well as the spectrum of the transfer matrix and the corresponding Bethe equations. As in the XXX case, the so-called quasi-classical limit gives the off-shell action of the generating function of the corresponding trigonometric Gaudin Hamiltonians with boundary terms.

  5. Pleural mesothelioma - case report.

    PubMed

    Klawiter, Anna; Damaszke, Tomasz

    2010-10-01

    Pleural mesothelioma is a very rare neoplasm; especially the local form. The diagnostics is difficult and the prognosis unfavourable. We presented a case of a man with dyspnoea and cough. His chest radiogram showed hydrothorax on the left side. Neither the examinations of the pleural liquid, nor the CT-guided fine needle biopsy established the diagnosis. CT showed features suggestive of pleural mesothelioma. The diagnosis was confirmed by thoracoscopy. Although no neoplastic cells were found in the thoracoscopic specimen from the supradiaphragmatic tumor, we assumed that to be a case of a diffuse, primarily local form of mesothelioma. Diagnostics of pleural mesothelioma is very difficult. CT and thoracoscopy seem to be very valuable diagnostic methods. It is worth remembering that pleural mesothelioma can have a local form which may transform into a diffuse one.

  6. Tinea Capitis in the form of Concentric Rings in an HIV Positive Adult on Antiretroviral Treatment

    PubMed Central

    Narang, Kirti; Pahwa, Manish; Ramesh, V

    2012-01-01

    Dermatophyte infection may present in the form of concentric rings caused by Trichophyton concentricum, known as Tinea Imbricata. In immunosuppressed patients, there are reports of lesions in the form of concentric rings caused by dermatophytes other than Trichophyton concentricum too, mostly by Trichophyton tonsurans, known as Tinea indesiciva or Tinea pseudoimbricata. We report a case of tinea capitis in a HIV-positive adult woman on antiretroviral therapy, who presented with concentric rings of papules and pustules with slight scaling on the scalp along with diffuse thinning of hair. Both Potassium hydroxide mount and culture showed the presence of Dermatophytes. Tinea capitis is considered rare in adults, but new cases are being reported in immunocompromised as well as in immunocompetent patients. The pertinent features of this case are: HIV-positive adult female on antiretroviral therapy, presenting with tinea capitis in the form of concentric rings; culture from the lesion grew Microsporum audouinii; responding to oral Terbinafine. PMID:22837564

  7. Power and knowledge in psychiatry and the troubling case of Dr Osheroff.

    PubMed

    Robertson, Michael

    2005-12-01

    To consider the state of knowledge in psychiatry with reference to the 'Osheroff debate' about the treatment of depression. A review of the key philosophical issues regarding the nature of knowledge applied to the Osheroff case. There is an apparent dichotomy between knowledge derived from a reductionist scientific method, as manifest in evidence-based medicine, and that of a narrative form of knowledge derived from clinical experience. The Focauldian notion of knowledge/power and knowledge as discourse suggests that scientific knowledge dominates over narrative knowledge in psychiatry. The implication of this applied to the Osheroff case is the potential annihilation of all forms of knowledge other than science. Knowledge in psychiatry is a pluralist, rather than singularly scientific enterprise. In the Osheroff case, the potential for scientific knowledge to abolish other forms of knowledge posed a serious threat of weakening the profession. In the light of the current debate about best practice, there is a need for reconsideration of the implications of Osheroff.

  8. Interface properties of SiO2/GaN structures formed by chemical vapor deposition with remote oxygen plasma mixed with Ar or He

    NASA Astrophysics Data System (ADS)

    Truyen, Nguyen Xuan; Taoka, Noriyuki; Ohta, Akio; Makihara, Katsunori; Yamada, Hisashi; Takahashi, Tokio; Ikeda, Mitsuhisa; Shimizu, Mitsuaki; Miyazaki, Seiichi

    2018-06-01

    The impacts of noble gas species (Ar and He) on the formation of a SiO2/GaN structure formed by a remote oxygen plasma-enhanced chemical vapor deposition (ROPE-CVD) method were systematically investigated. Atomic force microscopy revealed that ROPE-CVD with He leads to a smooth SiO2 surface compared with the case of Ar. We found that no obvious oxidations of the GaN surfaces after the SiO2 depositions with the both Ar and He cases were observed. The capacitance–voltage (C–V) curves of the GaN MOS capacitors formed by ROPE-CVD with the Ar and He dilutions show good interface properties with no hysteresis and good agreement with the ideal C–V curves even after post deposition annealing at 800 °C. Besides, we found that the current density–oxide electric field characteristics shows a gate leakage current for the Ar case lower than the He case.

  9. A rare cause of abdominal lymphadenopathy--tularemia: report of two pediatric cases.

    PubMed

    Gülhan, Belgin; Tezer, Hasan; Kanık-Yüksek, Saliha; Kılıç, Selçuk; Senel, Emrah

    2014-01-01

    Tularemia caused by Francisella tularensis occurs worldwide in the northern hemisphere, with great variation in geographic and temporal occurrence. It generally presents as an acute febrile disease with the major clinical presentations including the six classic forms of tularemia: ulceroglandular, glandular, oculoglandular, oropharyngeal, typhoidal, and pneumonic. In contrast to European countries, where the ulceroglandular form is more prominent, the oropharyngeal form is the most common presentation in Turkey. We present rare cases of oropharyngeal tularemia in a 16-year-old boy and nine-year-old girl. To the best of our knowledge, these are the firstly described abdominal lymphadenopathy cases from Turkey. The second case was admitted with erythema nodosum, and abdominal lymphadenopathy was detected during the investigation. Excisional lymph node biopsy revealed abdominal tularemia. It is necessary to consider tularemia in the differential diagnosis of abdominal lymphadenopathy in tularemia regions. We also conclude that oropharyngeal tularemia can cause lymphadenopathy in any part of the gastrointestinal tract.

  10. The Typology and Function of Private Speech in a Young Man with Intellectual Disabilities: An Empirical Case Study

    ERIC Educational Resources Information Center

    Lechler, Suzanne; Hare, Dougal Julian

    2015-01-01

    A naturalistic observational single case study was carried out to investigate the form and function of private speech (PS) in a young man with Dandy-Walker variant syndrome and trisomy 22. Video recordings were observed, transcribed and coded to identify all combinations of type and form of PS. Through comparison between theories of PS and the…

  11. Monocephalus diprosopus, a rare form of conjoined twins, and associated congenital anomalies.

    PubMed

    Rodríguez-Morales, Edda L; Correa-Rivas, María S; Colón-Castillo, Lillian E

    2002-09-01

    Craniofacial duplication (diprosopus) is a rare form of conjoined twins. A case of monocephalus diprosopus with anencephaly, cervicothoracolumbar rachischisis, and duplication of the respiratory tract and upper gastrointestinal tract is reported. The cardiovascular system remained single but the heart showed transposition of the great vessels. We present this case due to its rarity, and compare our pathologic findings with those already reported.

  12. [Basic thoughts on psychopharmacological interventions through psychotherapy of severe forms of post-traumatic stress disorder: a case study].

    PubMed

    Joksimovic, Ljiljana; Wöller, Wolfgang; Kunzke, Dieter

    2013-01-01

    The present paper focuses on clinical issues concerning the psychopharmacological treatment of severe forms of post-traumatic stress disorder (PTSD).Using a case study, we discuss problems in this field against the background of psychodynamic and psychotraumatological theories. We also present strategies for the appropriate use of psychotropic drugs in the psychotherapy of PTSD.

  13. Dexamethasone as adjuvant therapy in the treatment of invasive meningococcal diseases.

    PubMed

    Tolaj, Ilir; Dreshaj, Shemsedin; Qehaja, Emine; Tolaj, Jasmina; Doda-Ejupi, Teuta; Mehmeti, Murat

    2010-01-01

    With this study we want to evaluate the role of dexamethasone adjuvant treatment in different clinical forms of invasive meningococcal diseases. WORK METHODS: This was a randomized, open label trial that was conducted in 147 individuals with meningococcal sepsis. All of the cases have been divided in two groups: (1) Cases with meningococcal disease and CNS infection, and (2) Cases with meningococcal disease and no affection of the CNS. Cases from both groups were treated with dexamethasone, 0.15 mg/kg, every 6 h, for 4 (four) days, as adjuvant therapy. Cases which were not treated with dexamethasone were used as control group. From overall number of cases, in 130 of them, the meningococcal disease was accompanied with meningitis; in other 17 cases only signs of sepsis were present. In both clinical forms, the dexamethasone was used in 92 cases. The higher mortality rate is registered among the cases without meningitis, 17.65%, compared with 6.92% which is registered among cases with meningitis. The overall mortality rate among all cases was 8.2%. The significant difference was recorded only on CSF sugar level between two groups (treated or not with dexamethasone) on the day 1-4 of the hospitalization. Our epidemiological data are in correlation with data from other epidemiological studies. Most of the cases 69.4%, were more than 12 hours sick at home before the hospitalization, 7.5 % of cases were hospitalized within 12 hours from the onset of the diseases, while 23.1% of cases data are missing. This is in correlation with similar data from other studies. Dexamethasone has a limited effect on outcome of the invasive meningococcal disease. Dexamethasone had some effect only during the days of administration in cases with clinical form of sepsis with meningitis, by normalizing the values of CSF sugar earlier.

  14. Evaluation of matrix metalloproteinases (MMP)-2 and MMP-9 activity in serum and biochemical and hematological parameters in spontaneous canine cutaneous tumors before and after surgical treatment.

    PubMed

    Fathipour, Vahid; Khaki, Zohreh; Nassiri, Seyyed Mehdi

    2018-01-01

    Recently, matrix metalloproteinases (MMP), in particular the gelatinases MMP-2 and MMP-9, generally considered as tumor markers for clinical applications. A longitudinal 2-years follow-up survey was performed on dogs with cutaneous tumor. Serum samples were obtained from 22 dogs with different cutaneous tumors and 22 health dogs at the time of surgery and one month, three months and one year after surgery. Gelatin zymography, hematological and biochemical assessment were performed for all serum samples. The serum alkaline phosphatase activity in dogs with malignant tumors was significantly higher than that in dogs with benign tumors and control cases. Latent forms of MMP-2 and MMP-9 were detected in all of the tumor cases. Gelatin zymography showed active form of MMP-9 in 12 cases (three benign and nine malignant tumors) and active form of MMP-2 in one fibrosarcoma case. Serum activity of active-MMP-9 and total MMP-9 was significantly higher in dogs with cutaneous tumors than those in controls. Tumor cases had higher serum activity of active-MMP-9 rather than controls. MMPs and alkaline phosphatase activities in serum were decreased significantly after surgery. Only one case with perianal gland adenoma showed recurrence of tumor four months after surgery in which active form of MMP-9 had identified one month before recurrence. According to the findings, it will be useful to measure ALP, MMP-2 and MMP-9 activities in the serum of dogs with cutaneous tumor for determination of tumor behavior before surgical treatment.

  15. Hidden symmetries and Lie algebra structures from geometric and supergravity Killing spinors

    NASA Astrophysics Data System (ADS)

    Açık, Özgür; Ertem, Ümit

    2016-08-01

    We consider geometric and supergravity Killing spinors and the spinor bilinears constructed out of them. The spinor bilinears of geometric Killing spinors correspond to the antisymmetric generalizations of Killing vector fields which are called Killing-Yano forms. They constitute a Lie superalgebra structure in constant curvature spacetimes. We show that the Dirac currents of geometric Killing spinors satisfy a Lie algebra structure up to a condition on 2-form spinor bilinears. We propose that the spinor bilinears of supergravity Killing spinors give way to different generalizations of Killing vector fields to higher degree forms. It is also shown that those supergravity Killing forms constitute a Lie algebra structure in six- and ten-dimensional cases. For five- and eleven-dimensional cases, the Lie algebra structure depends on an extra condition on supergravity Killing forms.

  16. [The discharge form: advantages and limits legionellosis cases individuation].

    PubMed

    Trerotoli, P; Montagna, M T; Borella, P; Romano Spica, V; Stancanelli, G; Triassi, M; Serio, G; Napoli, C; Soldano, S; Tatò, D; Vercilli, F; Gentile, C; Quaranta, G; Volpe, M; Ambrosio, A; Santarpia, R; Montegrosso, S

    2003-01-01

    Despite legionellosis surveillance is active in Italy since many years, the disease notification appears still undervalued. A multicentric survey was carried out among 5 big Italian hospitals. It examined 11,435 discharge forms (1999-2001), reporting pneumonia diagnosis. Legionellosis (II class of notify system for infectious disease) was studied among pneumonia diagnosis by discharge forms. According to the ICD9-CM, there's no specific code for legionellosis (this disease is included among "others gram-negative pneumonia"). So the presumed pneumonia imputable to Legionella spp were the 2.7% of the whole number of analyzed discharge forms. Besides, the data regarding the other pneumonia showed that the etiological agent was specified only in the 11.2% of the case. This situation could be rectified both introducing adequate discharge forms codes and promoting the etiological diagnosis during the hospital stay.

  17. Diffuse and disseminated cutaneous leishmaniasis: clinical cases experienced in Ecuador and a brief review.

    PubMed

    Hashiguchi, Yoshihisa; Gomez, Eduardo L; Kato, Hirotomo; Martini, Luiggi R; Velez, Lenin N; Uezato, Hiroshi

    2016-01-01

    In Ecuador, cutaneous leishmaniasis (CL) is prevalent countrywide, but only one case of diffuse-CL and two cases of disseminated-CL were experienced during our research activities more than 30 years from 1982 to date. These three patients suffered from multiple lesions distributed at a wide range of the body surface, revealing difficulty to clinically differentiate each other. There is a considerable confusion of the use and/or differentiation of the terminologies (terms) between the two disease forms, diffuse-CL and disseminated-CL. One of the aims of the present study is to clarify the difference between the two disease forms, mainly based on the cases experienced in Ecuador. The disseminated-CL case newly reported here was clinically very similar to the diffuse-CL case, but the former showed the following marked differences from the latter: (1) the organisms isolated were identified as the parasites of Leishmania (Viannia) guyanensis/panamensis, which are also known as the causative agents of disseminated-CL in different endemic countries of the New World; (2) the patient was sensitive against antimonials; and (3) mucosal involvement was observed, which is never observed in diffuse-CL. In the text, three clinical cases, one diffuse-CL and two disseminated-CL, were presented. Furthermore, a bibliographic comparison of the features between the two disease forms was made, and a brief comment was also given.

  18. Bacterial Biofilms in Chronic Rhinosinusitis and Their Implications for Clinical Management.

    PubMed

    Karunasagar, Abhilasha; Garag, Santosh S; Appannavar, Suma B; Kulkarni, Raghavendra D; Naik, Ashok S

    2018-03-01

    To study the microbiological profile in patients with chronic rhino-sinusitis. To correlate disease severity with the presence of biofilms and host risk factors. To assess outcome of Sinus Surgery 2 weeks post operatively in terms of presence of bacteria and their ability to form biofilm. Prospective study. 50 cases of chronic rhino-sinusitis requiring Functional Endoscopic Sinus Surgery admitted in SDM Hospital, Dharwad, Karnataka were studied using intra-operative mucosal samples for microbiological analysis. The organisms isolated were tested for biofilm forming ability using three in vitro tests. Severity of disease was assessed using SNOT 22 scoring system. Of 50 cases studied, 66% showed presence of chronic rhino-sinusitis with polyposis and had higher SNOT scores compared to those without polyps. Bacterial isolates were obtained from only 17 samples. Staphylococcus species was isolated from 16 samples and Klebsiella pneumoniae from one. 11 Staph spp. isolates showed biofilm forming ability in vitro. Postoperative events in 3 cases yielded biofilm-forming Staphylococcus. Staphylococcus was the most dominant organism isolated and 11 isolates were biofilm formers. Thus the detection of biofilm forming organisms can be considered as a negative prognostic indicator and should forewarn the surgeon about the risk of recurrence.

  19. Impact of building forms on thermal performance and thermal comfort conditions in religious buildings in hot climates: a case study in Sharjah city

    NASA Astrophysics Data System (ADS)

    Mushtaha, Emad; Helmy, Omar

    2017-11-01

    The common system used for thermal regulation in mosques of United Arab Emirates (UAE) is the heating, ventilating and air-conditioning (HVAC) system. This system increases demands on energy consumption and increases CO2 emission. A passive design approach is one of the measures to reduce these problems. This study involved an analytical examination of building forms, followed by testing the impact of these forms on its thermal performance and indoor thermal comfort. The tests were conducted using energy simulations software packages. Passive parameters such as shading devices, thermal insulation and natural ventilation were applied in six cases, including the baseline case within each form. The obtained results showed a significant effect of mosque forms as well as passive design techniques on the thermal comfort within the structures. The findings confirmed that the use of passive design alone would not help achieve thermal comfort, but reduce the annual energy consumption by10%. By integrating a hybrid air-conditioning system as another supporting approach, the annual energy consumption could be reduced by 67.5%, which allows for the designing of a much smaller HVAC system.

  20. The neurophysiology of language processing shapes the evolution of grammar: evidence from case marking.

    PubMed

    Bickel, Balthasar; Witzlack-Makarevich, Alena; Choudhary, Kamal K; Schlesewsky, Matthias; Bornkessel-Schlesewsky, Ina

    2015-01-01

    Do principles of language processing in the brain affect the way grammar evolves over time or is language change just a matter of socio-historical contingency? While the balance of evidence has been ambiguous and controversial, we identify here a neurophysiological constraint on the processing of language that has a systematic effect on the evolution of how noun phrases are marked by case (i.e. by such contrasts as between the English base form she and the object form her). In neurophysiological experiments across diverse languages we found that during processing, participants initially interpret the first base-form noun phrase they hear (e.g. she…) as an agent (which would fit a continuation like … greeted him), even when the sentence later requires the interpretation of a patient role (as in … was greeted). We show that this processing principle is also operative in Hindi, a language where initial base-form noun phrases most commonly denote patients because many agents receive a special case marker ("ergative") and are often left out in discourse. This finding suggests that the principle is species-wide and independent of the structural affordances of specific languages. As such, the principle favors the development and maintenance of case-marking systems that equate base-form cases with agents rather than with patients. We confirm this evolutionary bias by statistical analyses of phylogenetic signals in over 600 languages worldwide, controlling for confounding effects from language contact. Our findings suggest that at least one core property of grammar systematically adapts in its evolution to the neurophysiological conditions of the brain, independently of socio-historical factors. This opens up new avenues for understanding how specific properties of grammar have developed in tight interaction with the biological evolution of our species.

  1. Meningoceles, meningomyeloceles, and encephaloceles: a neuro-dermatopathologic study of 132 cases.

    PubMed

    Berry, A D; Patterson, J W

    1991-06-01

    Because there have been few comprehensive histopathologic studies of meningomyeloceles and related malformations, we undertook a systematic study of these lesions. One hundred and thirty two cases were obtained from our surgical pathology files; these included 38 meningoceles, 71 meningomyeloceles, and 23 encephaloceles. Tissue sections were stained with hematoxylin and eosin; special stains included trichrome, alcian blue, Fontana-Masson, Nissl, Holzer, and immunoperoxidase for glial fibrillary acidic protein. Epithelial changes included ulceration, atrophy, or nevoid hyperplasia of the epidermis, and loss of appendages. Mesodermal features included fibrous zones resembling dura, subarachnoid tissue or scar (99% of cases), increased numbers of blood vessels (83%), hypertrophy of arrector pili muscle (42%), lipoma formation (38%), and immature skeletal muscle fibers (5%) that rarely intermingled with neuropil-like matrix. The latter tissue was identified in 71% of cases and included neurons, astrocytes, oligodendroglia, and ependyma. Forty-eight percent of cases included peripheral nerve fibers or roots, and some fibers formed onion bulb or Pacinian corpuscle-like structures. Meningothelial cells were observed in 26% of cases and sometimes formed recognizable whorls. Choroid plexus was noted in 3 cases, one example showing an unusual dystrophic calcification that formed long parallel spicules. Pigmented dendritic cells were observed within zones of fibrous tissue in 10% of cases. These malformations involve complex arrangements of cutaneous, neuroectodermal, and mesodermal elements. Because they may be encountered by dermatopathologists, familiarity with the microscopic features of dysraphic lesions is essential.

  2. [Hansen's disease in the northern region of Brazil--1986].

    PubMed

    Britto, R da S

    1989-12-01

    Some general facts about Hansen's Disease are presented: in the world, in the Americas, in 1986, with the purpose to focalize on the Northern Region of Brazil (Amazon Valley) where an attempt is made to specify, State, the clinical forms in the active registry, the respective coefficients of Prevalence, about the cases detected during the year, by clinical forms and the correspondent Coefficient of Incidence, the age range of less than 15 years, and above 15 years; and to analyze according to the township in the State of Amazonas in a series of 8 years, from 1979 to 1986, the registered cases under control and also without control, the new cases, by clinical form and Coefficient of Incidence, the positive cases among students in the capital and also in the country, and with more details, still by township and by Public Health Registry, in 1986, with the population, new cases, and Coefficient of Incidence, cases of the active registry, cases under control, Coefficient of Incidence, the relationship between patients/inhabitants, cases according to the decreasing intensity as far as the Prevalence and Health Department Regions: all this to give an idea, in detail, inclusive statistics, of the real position of Hansen's Disease in the Northern Region (Amazon Valley), with the highest figures of Prevalence and even of Incidence, in comparison with other Regions of the country, and to stress the grave situation of the endemic proportions of the disease, in Brazil in general and in that Regions, in particular.

  3. Incomplete form of Primary Hypertrophic Osteoarthropathy (Touraine-Solente-Gole Syndrome) Masquerading as Polyartrhalgia Diagnosed in Technetium-99m-Methylene Diphosphonate Scintigraphy: An Interesting Case Report.

    PubMed

    Sivathapandi, Thangalakshmi; Amalachandran, Jaykanth; Simon, Shelley; Elangovan, Indirani

    2018-01-01

    The primary hypertrophic osteoarthropathy (PHOA) (pachydermoperiostosis) is a rare genetic/hereditary disease characterized by skin changes (pachydermia), clubbing of fingers and periosteal thickening (periostitis) with sub-periosteal new bone formation. Here we describe a case of an adolescent male who presented with clubbing and polyarthralgia. On evaluation with scintigraphy and SPECT-CT, he was diagnosed to have incomplete form of PHOA(skeletal manifestations without skin changes). The identification of incomplete form of primary hypertrophic osteoarthropathy which can be easily misdiagnosed as rheumatoid arthritis is discussed here.

  4. Glauber exchange amplitudes. [electron scattering from H atoms

    NASA Technical Reports Server (NTRS)

    Madan, R. N.

    1975-01-01

    The extrapolation method of Ochkur, valid for intermediate energies (about 50 eV), is applied to the exchange form of the Glauber amplitudes. In the case of elastic scattering of electrons from hydrogen atoms at 54.4 Ev the 'post' and 'prior' forms of the exchange amplitude are equivalent, whereas for the case of inelastic scattering there is a minute discrepancy between the two forms of the amplitude. The results are compared with the close-coupling calculation. The investigation is expected to be useful for optically forbidden exchange-allowed transitions due to electron impact at intermediate energies.

  5. Clean process to destroy arsenic-containing organic compounds with recovery of arsenic

    DOEpatents

    Upadhye, R.S.; Wang, F.T.

    1996-08-13

    A reduction method is provided for the treatment of arsenic-containing organic compounds with simultaneous recovery of pure arsenic. Arsenic-containing organic compounds include pesticides, herbicides, and chemical warfare agents such as Lewisite. The arsenic-containing compound is decomposed using a reducing agent. Arsine gas may be formed directly by using a hydrogen-rich reducing agent, or a metal arsenide may be formed using a pure metal reducing agent. In the latter case, the arsenide is reacted with an acid to form arsine gas. In either case, the arsine gas is then reduced to elemental arsenic. 1 fig.

  6. Clean process to destroy arsenic-containing organic compounds with recovery of arsenic

    DOEpatents

    Upadhye, Ravindra S.; Wang, Francis T.

    1996-01-01

    A reduction method is provided for the treatment of arsenic-containing organic compounds with simultaneous recovery of pure arsenic. Arsenic-containing organic compounds include pesticides, herbicides, and chemical warfare agents such as Lewisite. The arsenic-containing compound is decomposed using a reducing agent. Arsine gas may be formed directly by using a hydrogen-rich reducing agent, or a metal arsenide may be formed using a pure metal reducing agent. In the latter case, the arsenide is reacted with an acid to form arsine gas. In either case, the arsine gas is then reduced to elemental arsenic.

  7. Case Meetings for Teaching English for Specific Academic Purposes in a Tertiary Aeronautical Engineering Programme

    ERIC Educational Resources Information Center

    Tatzl, Dietmar

    2015-01-01

    This article presents an innovative adaptation of the case method to teaching English for specific academic purposes. Widespread in its traditional form in various content disciplines, the case method bears the potential for truly student-centred language instruction. The current application transforms learners from case analysts to case authors…

  8. Laparoscopic cholecystectomy in a patient with Steinert myotonic dystrophy. Case report.

    PubMed

    Agrusa, A; Mularo, S; Alessi, R; Di Paola, P; Mularo, A; Amato, G; Romano, G

    2011-01-01

    Myotonic dystrophy (MD) is a serious multi-systemic autosomal dominant disease. The estimated incidence is 1 in every 8000 births, with an estimated prevalence of between 2.1 and 14.3 cases per 100,000 inhabitants. Signs and symptoms vary from a severe form of congenital myopathy, present from birth and often fatal, to a classic form and a delayed form, which generally presents after the age of 50 and in which the only sign is a cataract and life expectancy is completely normal. We describe the clinical case of a 40-year-old woman with Steinert myotonic dystrophy who underwent laparoscopic cholecystectomy (under general anesthesia) for symptomatic gallbladder stones. The conduct of anesthesia in such patients must be carefully considered, as hypothermia, shivering, electrical and mechanical stimulation, and the drugs used can all trigger myotonia.

  9. [Juvenile form of Sandhoff disease: first case reported in Argentina].

    PubMed

    Mugnaini, Julia; Pereyra, Marcela; Dodelson de Kremer, Raquel; Gamboni, Beatriz; Argaraña, Carlos E; Oller Ramírez, Ana M

    2017-10-01

    Sandhoff disease is a neurodegenerative, lysosomal and autosomal recessive disease caused by mutations in the HEXB gene. Three forms are recognized: infantile, juvenile and adult. Previously, an endogamous population in Córdoba, Argentina, was identified with a high incidence of Sandhoff disease, all reported cases were of the infantile type. In this work, we describe a child with the juvenile form of Sandhoff disease, the first case reported in Argentina. The patient is a 7-year-old boy presenting with ataxia, speech disturbances and global developmental delay, symptoms starting at the age of 2 years. Diagnosis was based on the hexosaminidase deficiency. Sequencing of genomic DNA revealed compound heterozygosity for two HEXB gene mutations: c.796T>G (p.Y266D) and c.1615C>T (p.R539C), both already reported. Sociedad Argentina de Pediatría.

  10. 21 CFR 312.62 - Investigator recordkeeping and record retention.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... provide for disposition of the unused supplies of the drug under § 312.59. (b) Case histories. An investigator is required to prepare and maintain adequate and accurate case histories that record all... drug or employed as a control in the investigation. Case histories include the case report forms and...

  11. Acquired toxoplasmosis of a submandibular lymph node in a 13-year-old boy: case report.

    PubMed

    Azaz, B; Milhem, I; Hasson, O; Kirsch, G

    1994-01-01

    Toxoplasmosis is a parasitic infection divided into congenital and acquired forms. In the latter form, malaise, fatigue, and lymphadenopathy are commonly found, and submandibular lymphadenopathy is sometimes a manifestation. In children, cervical lymph nodes usually are affected. This is a case of a 13-year-old boy suffering from acquired toxoplasmosis, in which submandibular lymphadenopathy was the only clinical sign of the disease. Meticulous history taking, clinical examination, and specific serological tests should be performed in these cases. Positive serological results will confirm toxoplasmosis infections. Conservative treatment must be attempted initially.

  12. Gunshot wound causing complete spinal cord injury without mechanical violation of spinal axis: Case report with review of literature

    PubMed Central

    Patil, Rahul; Jaiswal, Gaurav; Gupta, Tarun Kumar

    2015-01-01

    Penetrating spine injury (PSI) forms the third most common cause of spine injury, only next to road traffic accidents and fall. Gunshot wound (GSW) forms the major bulk of PSI. Due to easy availability of firearms and antisocial behavior, GSW which were predominant in military population is now increasingly seen in civilized society. Here, we present a detail case review of unique case of civilian GSW indirectly causing complete spinal cord injury due to shock wave generated by the bullet, along with its systematic management. PMID:26692690

  13. Closed-form solution of the Ogden-Hill's compressible hyperelastic model for ramp loading

    NASA Astrophysics Data System (ADS)

    Berezvai, Szabolcs; Kossa, Attila

    2017-05-01

    This article deals with the visco-hyperelastic modelling approach for compressible polymer foam materials. Polymer foams can exhibit large elastic strains and displacements in case of volumetric compression. In addition, they often show significant rate-dependent properties. This material behaviour can be accurately modelled using the visco-hyperelastic approach, in which the large strain viscoelastic description is combined with the rate-independent hyperelastic material model. In case of polymer foams, the most widely used compressible hyperelastic material model, the so-called Ogden-Hill's model, was applied, which is implemented in the commercial finite element (FE) software Abaqus. The visco-hyperelastic model is defined in hereditary integral form, therefore, obtaining a closed-form solution for the stress is not a trivial task. However, the parameter-fitting procedure could be much faster and accurate if closed-form solution exists. In this contribution, exact stress solutions are derived in case of uniaxial, biaxial and volumetric compression loading cases using ramp-loading history. The analytical stress solutions are compared with the stress results in Abaqus using FE analysis. In order to highlight the benefits of the analytical closed-form solution during the parameter-fitting process experimental work has been carried out on a particular open-cell memory foam material. The results of the material identification process shows significant accuracy improvement in the fitting procedure by applying the derived analytical solutions compared to the so-called separated approach applied in the engineering practice.

  14. Coherent structures and flow topology of transitional separated-reattached flow over two and three dimensional geometrical shapes

    NASA Astrophysics Data System (ADS)

    Diabil, Hayder Azeez; Li, Xin Kai; Abdalla, Ibrahim Elrayah

    2017-09-01

    Large-scale organized motions (commonly referred to coherent structures) and flow topology of a transitional separated-reattached flow have been visualised and investigated using flow visualisation techniques. Two geometrical shapes including two-dimensional flat plate with rectangular leading edge and three-dimensional square cylinder are chosen to shed a light on the flow topology and present coherent structures of the flow over these shapes. For both geometries and in the early stage of the transition, two-dimensional Kelvin-Helmholtz rolls are formed downstream of the leading edge. They are observed to be twisting around the square cylinder while they stay flat in the case of the two-dimensional flat plate. For both geometrical shapes, the two-dimensional Kelvin-Helmholtz rolls move downstream of the leading edge and they are subjected to distortion to form three-dimensional hairpin structures. The flow topology in the flat plate is different from that in the square cylinder. For the flat plate, there is a merging process by a pairing of the Kelvin-Helmholtz rolls to form a large structure that breaks down directly into many hairpin structures. For the squire cylinder case, the Kelvin-Helmholtz roll evolves topologically to form a hairpin structure. In the squire cylinder case, the reattachment length is much shorter and a forming of the three-dimensional structures is closer to the leading edge than that in the flat plate case.

  15. Flow and coherent structures around circular cylinders in shallow water

    NASA Astrophysics Data System (ADS)

    Zeng, Jie; Constantinescu, George

    2017-06-01

    Eddy-resolving numerical simulations are conducted to investigate the dynamics of the large-scale coherent structures around a circular cylinder in an open channel under very shallow flow conditions where the bed friction significantly affects the wake structure. Results are reported for three test cases, for which the ratio between the cylinder diameter, D, and the channel depth, H, is D/H = 10, 25, and 50, respectively. Simulation results show that a horseshoe vortex system forms in all test cases and the dynamics of the necklace vortices is similar to that during the breakaway sub-regime observed for cases when a laminar horseshoe vortex forms around the base of the cylinder. Given the shallow conditions and turbulence in the incoming channel flow, the necklace vortices occupy a large fraction of the flow depth (they penetrate until the free surface in the shallower cases with D/H = 25 and 50). The oscillations of the necklace vortices become less regular with increasing polar angle magnitude and can induce strong amplification of the bed shear stress beneath their cores. Strong interactions are observed between the legs of the necklace vortices and the eddies shed in the separated shear layers in the cases with D/H = 25 and 50. In these two cases, a vortex-street type wake is formed and strong three-dimensional effects are observed in the near-wake flow. A secondary instability in the form of arrays of co-rotating parallel horizontal vortices develops. Once the roller vortices get away from the cylinder, the horizontal vortices in the array orient themselves along the streamwise direction. This instability is not present for moderately shallow conditions (e.g., D/H ≈ 1) nor for very shallow cases when the wake changes to an unsteady bubble type (e.g., D/H = 50). For cases when this secondary instability is present, the horizontal vortices extend vertically over a large fraction of the flow depth and play an important role in the vertical mixing of fluid situated at the wake edges (e.g., by transporting the near-bed, lower-velocity fluid toward the free surface and vice versa). The largest amplification of the bed shear stress in the near-wake region is observed beneath these horizontal vortices, which means that they would play an important role in promoting bed erosion behind the cylinder in the case of a loose bed. Simulation results suggest that these co-rotating vortices form as a result of the interactions between the legs of the main necklace vortices and the vortical eddies contained into the newly forming roller at the back of the cylinder. The paper also analyzes how D/H affects the separation angle on the cylinder, the size of the recirculation bubble, the bed friction velocity distributions, and turbulence statistics.

  16. [Obsessive-compulsive symptoms, tics, stereotypic movements or need for absolute consistency? The occurrence of repetitive activities in patients with pervasive developmental disorders--case studies].

    PubMed

    Bryńska, Anita; Lipińska, Elzbieta; Matelska, Monika

    2011-01-01

    Repetitive and stereotyped behaviours in the form of stereotyped interests or specific routine activities are one ofthe diagnostic criteria in pervasive developmental disorders. The occurrence of repetitive behaviours in patients with pervasive developmental disorders is a starting point for questions about the type and classification criteria of such behaviours. The aim of the article is to present case studies of patients with pervasive developmental disorders and co-morbid symptoms in the form of routine activities, tics, obsessive-compulsive symptoms or stereotyped behaviours. The first case study describes a patient with Asperger's syndrome and obsessive compulsive symptoms. The diagnostic problems regarding complex motor tics are discussed in the second case study which describes a patient with Asperger's syndrome and Gilles de la Tourette syndrome. The third and fourth case study describes mono-zygotic twins with so called High Functioning Autism whose repetitive activities point to either obsessive compulsive symptoms, stereotypic movements, need for absolute consistency or echopraxia. The possible comorbidity of pervasive developmental disorders and symptoms in the form of repetitive behaviours, possible interactions as well as diagnostic challenges is discussed in the article.

  17. 26 CFR 1.6081-5 - Extensions of time in the case of certain partnerships, corporations and U.S. citizens and...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... year and check the appropriate box on Form 4868, “Application for Automatic Extension of Time To File a U.S. Individual Income Tax Return,” or Form 7004, “Application for Automatic Extension of Time to... 26 Internal Revenue 13 2011-04-01 2011-04-01 false Extensions of time in the case of certain...

  18. Absent circle of Willis with vascular pollarding in an adult with colpocephaly: A developmental perspective

    PubMed Central

    Verghese, Renjan; Paul, Divyan

    2015-01-01

    Absent circle of Willis (COW) has been described in cases of severe forms of cerebral developmental anomalies such as alobar prosencephaly. However, there are no reports of absent COW in patients with a milder form of cerebral abnormality such as colpocephaly. We report a unique case of an adult with colpocephaly and absent COW and discuss their association from a developmental perspective. PMID:26443299

  19. Clinical specificities of Tinea capitis in Georgia population.

    PubMed

    Kudava, Kh

    2013-11-01

    The aim of the study was to reveal peculiarities of the clinical symptoms and forms of Tinea capitis caused by etiological agents that are common in our country. The study was conducted on 176 ambulatory patients who approached the National Centre in 2009-2013. Inclusion criterion was simultaneous presence of clinical symptoms and positive result of microscopic study. For cultural examination was used Sabouraud's dextrose agar with the antibiotic chloramphenicol. Clinical manifestations were divided into inflammatory and non-inflammatory (i.e. slightly manifested inflammatory signs) lesions. 85(48,3%) inflammatory and 91(51,7%) non-inflammatory cases of Tinea capitis were revealed. Clinical forms were distributed in following way: kerion 73 (41,5%), grey patch with single lesions 71 (40,3%), seborrheic dermatitis-like form 14 (8%), agminate folliculites 12 (6,8%) and black-dot dermatophytosis 6 (3,4%). In 41(89,1%) of the cases etiological agent of the kerion was Trichophyton mentagrophytes; in 41(85,4%) of the cases etiological agent for the grey patch with single lesions was Microsporum canis. Important clinical and etiological relationship was revealed between kerion and Trichophyton mentagrophytes, as well as between grey patch with single lesions and Microsporum canis. In case of inflammatory forms (predominantly kerion) caused by Trichophyton verrucosum and Trichophyton mentagrophytes ID reaction was manifested by disseminated follicular papules.

  20. A mixed-methods evaluation of health-related quality of life for male veterans with and without intestinal stomas.

    PubMed

    Krouse, Robert S; Grant, Marcia; Wendel, Christopher S; Mohler, M Jane; Rawl, Susan M; Baldwin, Carol M; Coons, Stephen Joel; McCorkle, Ruth; Ko, Clifford Y; Schmidt, C Max

    2007-12-01

    Intestinal stomas have a major impact on Cases' lives. It is essential to better understand the areas in which interventions may help to minimize the negative consequences. This was a case-control survey study using validated instruments (City of Hope Quality of Life-Ostomy and Short Form 36 for Veterans). Cases were accrued from Veterans Affairs Medical Centers in Tucson, Indianapolis, and Los Angeles. Eligibility included a major intra-abdominal surgical procedure that led to an ostomy (cases), or a similar procedure that did not mandate a stoma (controls). Analysis included quantitative and qualitative responses. The response rate was 48 percent (511/1,063). Cases and controls had relatively similar demographic characteristics. Because of low numbers of female respondents (13 cases and 11 controls), only results for males are reported. Based on both the City of Hope Quality of Life-Ostomy and Short Form 36 for Veterans, cases reported significantly poorer scores on scales/domains reflecting psychologic and social functioning and well being. Additionally, cases reported poorer scores on Short Form 36 for Veterans scales reflecting physical functioning and significantly lower scores on multiple items in the social domain of the City of Hope Quality of Life-Ostomy compared with controls. Two-thirds of cases replied to an open-ended question on their "greatest challenge" related to their ostomy, which led to further clarification of major issues. Multiple health-related quality of life problems were reported by male veterans with intestinal stomas. The greatest differences between cases and controls were observed in the social and psychologic domains/scales. Findings from this study provide a greater understanding of the challenges faced by ostomates and will inform the development and evaluation of urgently needed intervention strategies.

  1. Refractory Depressed and Anxious States in Hyperthymic Women: A Case Series Generated by a Speaking Engagement

    PubMed Central

    Manning, J. Sloan

    2000-01-01

    The author discusses 4 referrals that were the direct result of a case description from his own practice that he presented during a lecture on the treatment of mixed anxious and depressive illness in primary care. The cases depict energetic, productive women who suffer fatigue and episodic depressions. These cases suggest that hyperthymic temperaments complicated by depressive episodes represent a form of mood disorder presentation that is highly recognizable and responsive to pharmacologic intervention. Such premorbid temperamental hypomanic tendencies may represent a soft form of bipolar illness that requires somatic strategies in line with those of classic manic depressive illness. The cases underscore the challenge of treating mood disorders and the need for treatment research to reach primary care practitioners, who see the majority of depressed and anxious patients. PMID:15014663

  2. Exploring Equivalent Forms Reliability Using a Key Stage 2 Reading Test

    ERIC Educational Resources Information Center

    Benton, Tom

    2013-01-01

    This article outlines an empirical investigation into equivalent forms reliability using a case study of a national curriculum reading test. Within the situation being studied, there has been a genuine attempt to create several equivalent forms and so it is of interest to compare the actual behaviour of the relationship between these forms to the…

  3. 49 CFR 31.26 - Filing, form, and service of papers.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 1 2011-10-01 2011-10-01 false Filing, form, and service of papers. 31.26 Section... Filing, form, and service of papers. (a) Filing and form. (1) A party filing any document under this part... paper filed in the proceeding shall contain a caption setting forth the title of the action, the case...

  4. 20 CFR 498.211 - Form, filing and service of papers.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Form, filing and service of papers. 498.211... AND RECOMMENDED EXCLUSIONS § 498.211 Form, filing and service of papers. (a) Form. (1) Unless the ALJ... action, the case number, and a designation of the pleading or paper. (3) Every document will be signed by...

  5. 43 CFR 35.26 - Form, filing and service of papers.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 43 Public Lands: Interior 1 2011-10-01 2011-10-01 false Form, filing and service of papers. 35.26... FRAUDULENT CLAIMS AND STATEMENTS § 35.26 Form, filing and service of papers. (a) Form. (1) Every pleading and paper filed in the proceeding shall contain a caption setting forth the title of the action, the case...

  6. The topological pressure-temperature phase diagram of ritonavir, an extraordinary case of crystalline dimorphism.

    PubMed

    Céolin, R; Rietveld, I B

    2015-01-01

    A topological pressure-temperature phase diagram involving the phase relationships of ritonavir forms I and II has been constructed using experimental calorimetric and volumetric data available from the literature. The triple point I-II-liquid is located at a temperature of about 407 K and a pressure as extraordinarily small as 17.5 MPa (175 bar). Thus, the less soluble solid phase (form II) will become metastable on increasing pressure. At room temperature, form I becomes stable around 100 MPa indicating that form II may turn into form I at a relatively low pressure of 1000 bar, which may occur under processing conditions such as mixing or grinding. This case is a good example for which a proper thermodynamic evaluation trumps "rules of thumb" such as the density rule. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  7. Symmetric and antisymmetric forms of the Pauli master equation.

    PubMed

    Klimenko, A Y

    2016-07-21

    When applied to matter and antimatter states, the Pauli master equation (PME) may have two forms: time-symmetric, which is conventional, and time-antisymmetric, which is suggested in the present work. The symmetric and antisymmetric forms correspond to symmetric and antisymmetric extensions of thermodynamics from matter to antimatter - this is demonstrated by proving the corresponding H-theorem. The two forms are based on the thermodynamic similarity of matter and antimatter and differ only in the directions of thermodynamic time for matter and antimatter (the same in the time-symmetric case and the opposite in the time-antisymmetric case). We demonstrate that, while the symmetric form of PME predicts an equibalance between matter and antimatter, the antisymmetric form of PME favours full conversion of antimatter into matter. At this stage, it is impossible to make an experimentally justified choice in favour of the symmetric or antisymmetric versions of thermodynamics since we have no experience of thermodynamic properties of macroscopic objects made of antimatter, but experiments of this kind may become possible in the future.

  8. In Case You Are Interested: Results of a Survey of Case Study Teachers

    ERIC Educational Resources Information Center

    Herreid, Clyde Freeman; Schiller, Nancy A.; Herreid, Ky F.; Wright, Carolyn

    2011-01-01

    Case study teaching had a long tradition in law and business before it made the jump to medical school education in the form of Problem-Based Learning (PBL) in the 1970s. Today, both the University of Delaware's Clearinghouse and the University of Buffalo's National Center for Case Study Teaching in Science (NCCSTS) have hundreds of cases and…

  9. Cutaneous double-hit B-cell lymphoma: an aggressive form of B-cell lymphoma with a propensity for cutaneous dissemination.

    PubMed

    Magro, Cynthia M; Wang, Xuan; Subramaniyam, Shivakumar; Darras, Natasha; Mathew, Susan

    2014-04-01

    Diffuse large cell B-cell lymphoma of the skin is most commonly represented by diffuse large cell variants of primary cutaneous follicle center cell lymphoma and the leg-type lymphoma. In a minority of cases, the infiltrates are an expression of stage 4 disease of established extracutaneous B-cell lymphoma. We describe 3 patients with an aggressive form of B-cell lymphoma secondarily involving the skin. Two of the patients were in the ninth decade of life, whereas 1 patient was 34 years of age. In the elderly patients, there was an antecedent and/or concurrent history of follicular lymphoma, whereas in the younger patient, the tumor was a de novo presentation of this aggressive form of lymphoma. The elderly patients succumbed to their disease within less than a year from the time of diagnosis, whereas 1 patient is alive but with persistent and progressive disease despite chemotherapeutic intervention. The infiltrates in all 3 cases were diffuse and composed of large malignant hematopoietic cells that exhibited a round nucleus with a finely dispersed chromatin. Phenotypically, the tumor cells were Bcl-2 and CD10 positive, whereas Bcl-6 and Mum-1 showed variable positivity. One case showed combined Mum-1 positivity along with an acute lymphoblastic lymphoma phenotype, including the absence of CD20 expression. In each case, there was a c-MYC and BCL2/IGH rearrangement diagnostic of double-hit lymphoma. In one case, there was an additional BCL6 rearrangement, defining what is in essence triple-hit lymphoma. In conclusion, double-hit lymphoma is an aggressive form of B-cell neoplasia resistant to standard chemotherapy regimens, which in many but not all cases represents tumor progression in the setting of a lower grade B-cell malignancy.

  10. Family history is under-estimated in children with isolated hypospadias: a French multicenter report of 88 families.

    PubMed

    Ollivier, Margot; Paris, Francoise; Philibert, Pascal; Garnier, Sarah; Coffy, Amandine; Fauconnet-Servant, Nadège; Haddad, Mirna; Guys, Jean Michel; Reynaud, Rachel; Faure, Alice; Merrot, Thierry; Wagner, Kathy; Bréaud, Jean; Valla, Jean Stéphane; Dobremez, Eric; Gaspari, Laura; Daures, Jean-Pierre; Sultan, Charles; Kalfa, Nicolas

    2018-04-30

    Whereas familial forms of complex disorders/differences of sex development have been widely reported, data regarding isolated hypospadias are sparse and a family history is thought to be less frequent. We aimed 1-to determine the frequency of hypospadias in families of hypospadiac boys 2-to determine if theses familial forms exhibit a particular phenotype 3-to evaluate the prevalence of genetic defects of the main candidate genes. A prospective inclusion of 395 hypospadiac boys screened for family history with a standardized questionnaire, extensive clinical description, family tree and sequencing of AR, SF1, SRD5A2 and MAMLD1 was performed. Family history of hypospadias was more frequent than expected (22.3%, n=88). In 19.3% of cases, the familial cases were multiple (n=17). Familial hypospadias were related to the paternal side in 59.1% of cases including the father himself (30.7%), paternal uncles and cousins. Prematurity, assisted-reproductive techniques, other congenital abnormalities and growth retardation were not more frequent in familial hypospadias than in sporadic cases. The severity of phenotype was similar in both groups. The results of the genetic analysis combined to previous data on AR sequencing showed that familial cases tend to reveal more frequently genetic defects than sporadic cases (5.68% vs 1,63%, p=0,048). Familial forms of hypospadias are far more frequent than previously reported. Even minor and isolated hypospadias justify a full clinical investigation of the family history. Detecting these hereditary forms may help to find out the underlying genetic defects and may improve the follow-up and counseling of these patients. Copyright © 2018 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

  11. An eCommerce Development Case: Your Company's eCommerce Web Site

    ERIC Educational Resources Information Center

    Ballenger, Robert M.

    2007-01-01

    This case provides a real-world semester long project-oriented case study for students enrolled in an electronic commerce course that has a significant development component. The case provides the technical framework in the form of functional requirements for students to design and build a fully functional transaction processing e-commerce Web…

  12. THE RESERVE MINING CASE: SCIENTIFIC ISSUES THAT CREATED AND TRANSFORMED THE LANDMARK CASE AND STILL PERSIST TODAY

    EPA Science Inventory

    The Reserve Mining Case is regarded as the first landmark environmental and public health case and originated from Lake Superior Enforcement Conferences conducted under the Federal Water Pollution Control Act before U.S. EPA was formed. In 1973 just before the federal trial bega...

  13. Fat-forming Solitary Fibrous Tumor of the Kidney - A Case Report and Literature Review.

    PubMed

    Bacalbasa, Nicolae; Balescu, Irina; Jinescu, George; Marcu, Madalina; Contolenco, Andreea; Pop, Doina; Dobritoiu, Dragos; Ionescu, Olivia; Ionescu, Paris; Stoica, Claudia

    2018-01-01

    Fat-forming solitary fibrous tumors arising from the kidney are extremely rare, with only few cases reported so far. We report the case of a 49-year-old patient investigated for lumbar pain and diagnosed preoperatively with a large retroperitoneal tumor destroying the right kidney. The patient was submitted to surgery, the tumor being resected en bloc with right nephrectomy. The histopathological studies demonstrated the presence of a hemangiopericytoma-like tumor with adipocytary component; the immunohistochemical studies demonstrated the presence of cluster of differentiation 34 (CD34), while human melanoma black (HMB45) staining was negative. Therefore, the diagnostic of fat-forming solitary fibrous tumor of the kidney was established. The postoperative outcome was uneventful, the patient being discharged on the sixth postoperative day. In conclusion, although fat-forming solitary fibrous tumor of the kidney is a very rare entity, this diagnosis should be taken into consideration whenever a large retroperitoneal mass with high adipose content and renal invasion is described at the preoperative studies. Copyright© 2018, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

  14. Feline sporotrichosis: histopathological profile of cutaneous lesions and their correlation with clinical presentation.

    PubMed

    Miranda, Luisa H M; Conceição-Silva, Fátima; Quintella, Leonardo P; Kuraiem, Bianca P; Pereira, Sandro A; Schubach, Tânia M P

    2013-07-01

    Cutaneous lesions of feline sporotrichosis show high fungal load and are associated with severe disease and elevated zoonotic potential. The present study describes the histopathology and fungal load of the lesions in different clinical presentations of feline sporotrichosis. Cats with sporotrichosis were separated into groups L1, L2 and L3 (lesions in one, two and three or more locations, respectively) and subjected to skin biopsies for histopathology. Eighty-six cats were included in the study. Lesions were suppurative granulomatous in 84 cases and poorly formed granulomas were predominant. The well-formed granulomas were associated with group L1. The high fungal load was predominant in group L3 and in poorly formed granuloma cases and did not occur in well-formed granulomas cases. The good general condition was associated with low fungal load. These findings suggest that the fungal load control in animals with more localized lesions and well-organized response is linked with the improvement in the outcome of infected cats. Copyright © 2013 Elsevier Ltd. All rights reserved.

  15. [Prosthetic rehabilitation of patients with parodontitis based upon the use of 3D-technologies--clinical case example].

    PubMed

    Riakhovskiĭ, A N

    2011-01-01

    Clinical case of prosthetic rehabilitation of patient (female) with generalized parodontitis complicated by defects and deformations of dentitions was offered. Using 3D-technologies position of teeth was corrected with the help of a series of temporary transparent splints-modifiers with subsequent guy splintage and esthetic 3D-planning of front teeth forms. Teeth forms correction was made by composite using preliminary prepared templet.

  16. Restoration of the central slip in congenital form of boutonniere deformity: case report.

    PubMed

    Kim, Jong-Pil; Go, Jai-Hyang; Hwang, Chang-Hwan; Shin, Won-Jeong

    2014-10-01

    We present a case of a congenital form of a boutonniere deformity involving both little fingers with a poorly differentiated extensor mechanism and the absence of the tendinous attachment on the dorsal aspect of the middle phalanx. This complex deformity was evaluated histologically followed by successful reconstruction of the central slip. Copyright © 2014 American Society for Surgery of the Hand. Published by Elsevier Inc. All rights reserved.

  17. An initial study of void formation during solidification of aluminum in normal and reduced-gravity

    NASA Technical Reports Server (NTRS)

    Chiaramonte, Francis P.; Foerster, George; Gotti, Daniel J.; Neumann, Eric S.; Johnston, J. C.; De Witt, Kenneth J.

    1992-01-01

    Void formation due to volumetric shrinkage during aluminum solidification was observed in real time using a radiographic viewing system in normal and reduced gravity. An end chill directional solidification furnace with water quench was developed to solidify aluminum samples during the approximately 16 seconds of reduced gravity (+/- 0.02g) achieved by flying an aircraft through a parabolic trajectory. Void formation was recorded for two cases: first a nonwetting system; and second, a wetting system where wetting occurs between the aluminum and crucible lid. The void formation in the nonwetting case is similar in normal and reduced gravity, with a single vapor cavity forming at the top of the crucible. In the wetting case in reduced gravity, surface tension causes two voids to form in the top corners of the crucible, but in normal gravity only one large voids forms across the top.

  18. Design of case report forms based on a public metadata registry: re-use of data elements to improve compatibility of data.

    PubMed

    Dugas, Martin

    2016-11-29

    Clinical trials use many case report forms (CRFs) per patient. Because of the astronomical number of potential CRFs, data element re-use at the design stage is attractive to foster compatibility of data from different trials. The objective of this work is to assess the technical feasibility of a CRF editor with connection to a public metadata registry (MDR) to support data element re-use. Based on the Medical Data Models portal, an ISO/IEC 11179-compliant MDR was implemented and connected to a web-based CRF editor. Three use cases were implemented: re-use at the form, item group and data element levels. CRF design with data element re-use from a public MDR is feasible. A prototypic system is available. The main limitation of the system is the amount of available MDR content.

  19. Canonical multi-valued input Reed-Muller trees and forms

    NASA Technical Reports Server (NTRS)

    Perkowski, M. A.; Johnson, P. D.

    1991-01-01

    There is recently an increased interest in logic synthesis using EXOR gates. The paper introduces the fundamental concept of Orthogonal Expansion, which generalizes the ring form of the Shannon expansion to the logic with multiple-valued (mv) inputs. Based on this concept we are able to define a family of canonical tree circuits. Such circuits can be considered for binary and multiple-valued input cases. They can be multi-level (trees and DAG's) or flattened to two-level AND-EXOR circuits. Input decoders similar to those used in Sum of Products (SOP) PLA's are used in realizations of multiple-valued input functions. In the case of the binary logic the family of flattened AND-EXOR circuits includes several forms discussed by Davio and Green. For the case of the logic with multiple-valued inputs, the family of the flattened mv AND-EXOR circuits includes three expansions known from literature and two new expansions.

  20. [Study of leprosy at the "Emilio d'Audinot" polyclinic].

    PubMed

    Guerra Núñez, M; Mora Castillo, N; Abijana Damien, G

    1993-01-01

    A study on the prevalence of leprosy is performed in "Emilio Daudinot" polyclinics, Guantanamo. The behaviour of leprosy according to clinical manifestations and results showing that lepromatous leprosy is the most frequent form, as well as the number of positive patients and the ones who present reactional status, are reported. The clinical course according to skin and general manifestations is analyzed, and it was determined that the greatest number of cases improved with treatment. Likewise, it was found that the greatest number of positive patients require a 1-4 year period for becoming negative. The immunologic status of cases studied according to the different clinical forms is reported and it was observed that the greatest number of cases are immunologically depressed which agrees with the fact that most of patients have the lepromatous form. Nurses play a very important role for the control and treatment of these patients.

  1. An exact closed form solution for constant area compressible flow with friction and heat transfer

    NASA Technical Reports Server (NTRS)

    Sturas, J. I.

    1971-01-01

    The well-known differential equation for the one-dimensional flow of a compressible fluid with heat transfer and wall friction has no known solution in closed form for the general case. This report presents a closed form solution for the special case of constant heat flux per unit length and constant specific heat. The solution was obtained by choosing the square of a dimensionless flow parameter as one of the independent variables to describe the flow. From this exact solution, an approximate simplified form is derived that is applicable for predicting subsonic flow performance characteristics for many types of constant area passages in internal flow. The data included in this report are considered sufficiently accurate for use as a guide in analyzing and designing internal gas flow systems.

  2. Mitochondrial gene rearrangements confirm the parallel evolution of the crab-like form.

    PubMed Central

    Morrison, C L; Harvey, A W; Lavery, S; Tieu, K; Huang, Y; Cunningham, C W

    2002-01-01

    The repeated appearance of strikingly similar crab-like forms in independent decapod crustacean lineages represents a remarkable case of parallel evolution. Uncertainty surrounding the phylogenetic relationships among crab-like lineages has hampered evolutionary studies. As is often the case, aligned DNA sequences by themselves were unable to fully resolve these relationships. Four nested mitochondrial gene rearrangements--including one of the few reported movements of an arthropod protein-coding gene--are congruent with the DNA phylogeny and help to resolve a crucial node. A phylogenetic analysis of DNA sequences, and gene rearrangements, supported five independent origins of the crab-like form, and suggests that the evolution of the crab-like form may be irreversible. This result supports the utility of mitochondrial gene rearrangements in phylogenetic reconstruction. PMID:11886621

  3. [Pyoderma gangrenosum following hematopoietic stem cell transplantation].

    PubMed

    Eddou, H; Ennouhi, A; Sina, M; Zinebi, A; El Benaye, J; Moudden, M K; Doghmi, K; Malfuson, J-V; Mikdame, M; El Baaj, M

    2018-05-07

    Pyoderma gangrenosum (PG) is a rare form of neutrophilic dermatosis and is a potential complication in a number of systemic diseases. These include blood diseases, which represent 3.5% of cases, with the main forms being monoclonal gammopathy and acute myeloid leukemia. Herein we report a case of pyoderma gangrenosum in a female patient who had undergone haematopoietic stem cell allograft six months earlier as part of her treatment for acute T-cell leukemia. This condition forms one of the general disorders potentially associated with PG and is a dermatological disorder that can occur in marrow graft patients. Copyright © 2018 Elsevier Masson SAS. All rights reserved.

  4. GhostWriter-2.0: Product Reviews with Case-Based Support

    NASA Astrophysics Data System (ADS)

    Bridge, Derek; Healy, Paul

    A lot of user-generated content on the Web takes the form of records of personal experiences. Case-Based Reasoning offers a way of helping one user to reuse another's experiences from the Web. In this paper, we present GhostWriter-2.0, a Case-Based Reasoning system that supports a user who is writing a product review. GhostWriter-2.0 makes suggestions to the user, in the form of short phrases that are mined from other reviews. The purpose of the suggestions is to prompt the user to write a more comprehensive and helpful review than she might otherwise have done. We explain how GhostWriter-2.0's case base is populated with relevant and helpful reviews from Amazon. We show how it extracts and scores phrases in these reviews to decide which to suggest to the user.We report a trial with real users, in which users made greater use of GhostWriter-2.0's suggested phrases than they did of phrases suggested by a system that used a more random form of selection.

  5. Papular sarcoidosis of the knees. A frequent form of presentation of systemic sarcoidosis.

    PubMed

    Marcoval, Joaquim; Mañá, Juan

    2016-03-29

    In recent years we have observed with increasing frequency granulomatous papular lesions involving the knees, for which we proposed the term papular sarcoidosis of knees. To evaluate the clinicopathological features of papular sarcoidosis of the knees. Patients with papular lesions of the knees and histopathologically sarcoid granulomas were included in the study. Systemic sarcoidosis was investigated in all cases. Clinical charts were retrospectively retrieved. Biopsy specimens were evaluated under polarized light to detect foreign bodies. Fifty-three patients fulfilled inclusion criteria. In 36 cases systemic sarcoidosis was diagnosed and these cases were considered as papular sarcoidosis of the knees. Foreign particles were observed in 21 of these 36 patients. In only 9/36 patients did the activity of systemic disease persist over two years. In 17 cases sarcoidosis could not be demonstrated during follow-up. Papular sarcoidosis of the knees can be considered a relatively frequent form of cutaneous sarcoidosis usually present at the beginning of the disease that can be useful for the diagnosis of sarcoidosis. It is mainly observed in acute forms of sarcoidosis and can be considered a sign of good prognosis.

  6. Antioxidant enzymes levels in children with juvenile rheumatoid arthritis.

    PubMed

    Goţia, S; Popovici, I; Hermeziu, B

    2001-01-01

    Pathogenic mechanism of chronic inflammation is associated with increased production of superoxide anion and hydrogen peroxide. In the neutralization process of that anions, superoxid dismutase (SOD), catalase (CAT), and glutation peroxidase (GPx) are key enzymes. Aim of study consists of establishing of some clinic-biological correlations in JRA chronic inflammation in childhood between clinical status and determination of lipoperoxidation products and antioxidative enzymes in the blood. Blood samples were obtained from 20 patients admitted in 2nd Clinic of Pediatrics, 4-6 months after onset of disease, diagnosed with JRA, oligoarticular form (6 cases), poliarticular form (9 cases) and systemic form (5 cases), as compared to 10 control subjects. SOD, CAT, GPx were measured comparing with malonildialdehyde (MDA), seric glutation (GSH) and usual inflammatory tests (ESR, fibrinogen, CRP). Determinations were repeated after 6 weeks of treatment. In all our cases, level of antioxidant enzymes (CAT, GPx) was decreased at time of diagnosis, concomitant with increased MDA, SOD and inflammatory tests. In most of cases, after 6 weeks of correct anti-inflammatory treatment, levels of enzymatic antioxidant markers were still decreased, as compared to usual inflammatory tests that came back to normal. Persistent decreased antioxidant enzymatic activity was found in cases that need immunomodulatory activity (Methotrexat). Determination of antioxidant enzymes level can be considered an evolution marker in JRA. More studies are necessary to find if antioxidant potential of blood can be used as following marker for immunosuppressive therapy.

  7. 20 CFR 655.740 - What actions are taken on labor condition applications?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... employer, a determination shall be made by the ETA Certifying Officer whether to certify the labor... application. Where all items on Form ETA 9035 or Form ETA 9035E have been completed, the form is not obviously inaccurate, and in the case of Form ETA 9035, it contains the signature of the employer or its authorized...

  8. A Case of Inconsistent Equatings: How the Man with Four Watches Decides What Time It Is

    ERIC Educational Resources Information Center

    Livingston, Samuel A.; Antal, Judit

    2010-01-01

    A simultaneous equating of four new test forms to each other and to one previous form was accomplished through a complex design incorporating seven separate equating links. Each new form was linked to the reference form by four different paths, and each path produced a different score conversion. The procedure used to resolve these inconsistencies…

  9. Developing an experimental case in aluminium foils 1100 to determine the maximum angle of formability in a piece by Dieless-SPIF process

    NASA Astrophysics Data System (ADS)

    Gabriel, Paramo; Adrian, Benitez

    2014-07-01

    Incremental sheet forming by the method of single point incremental forming Dieless-SPIF, is a widely studied process, experimented and developed in countries with high manufacturing technologies, with friendly costs when the productive configuration in a productivity system is based in small production batches. United states, United kingdom and France lead this type of studies and cases, developing various proof with experimental geometries, different from the national environment such as Colombia, Bolivia, Chile, Ecuador and Peru where this process where discretely studied. Previously mentioned, it pretends develop an experimental case of a particular geometry, identifying the maximum formability angle of material permissible for the forming of a piece in one pass, the analysis of forming limit curve (FLC), with the objective to emphasizes in this innovative method based in CAD-CAM technologies, compare with other analogous process of deformation sheet metal like embossing, take correct decisions about the viability and applicability of this process (Dieless) in a particular industrial piece, which responses to the necessities of productive configurations mentioned and be highly taken like a manufacturing alternative to the other conventional process of forming sheet metal like embossing, for systems with slow batches production.

  10. Clinico-pathological Characteristics of Congenital Pulmonary Lymphangiectasis: Report of Two Cases

    PubMed Central

    Eom, Minseob; Choi, Yoo Duk; Kim, Youn Shin; Cho, Mee-Yon; Lee, Han Young

    2007-01-01

    Congenital pulmonary lymphangiectasis (CPL) is a rare, poorly documented disease, characterized by abnormal dilatation of pulmonary lymphatics without lymphatic proliferation. This disease is seen almost exclusively in infancy and early childhood. It can usually be divided into primary (congenital) and secondary forms. The primary form presents in neonates, and the patients mostly die due to the respiratory distress, shortly after birth. The authors experienced two cases of primary CPL in a 13-day-old male neonate and a one-day-old male neonate, showing prominent lymphatic dilatation in the septal, subpleural, and peri-bronchial tissue throughout both lungs. The latter case was associated with congenital cardiac anomaly including single ventricle. These are unique cases of CPL in Korea of which the diagnosis was established through post-mortem examination. Therefore, the authors report these two cases with primary CPL with a review of the literature. PMID:17728521

  11. [Subcutaneous phaeohyphomycosis caused by Phaeoacremonium parasiticum].

    PubMed

    Alayeto Ortega, Jose; Alier Fabregó, Albert; Puig Verdie, Lluis; Sorli Redo, Maria Luisa; Horcajada Gallego, Juan Pablo; Portillo Bordonabe, M Eugenia

    2015-01-01

    From the available literature, it is demonstrated that dematiaceous fungal infections mostly affect immunosuppressed patients. These infections can occur in different forms, from subcutaneous infection to disseminated forms that may compromise the life of the patient. In many cases the infection is related to the inoculation of the microorganism by diverse traumatic mechanisms, which determines the course of the infection to be slower in some cases. We describe two cases of phaeohyphomycosis caused by Phaeoacremonium parasiticum: A cancer patient with subcutaneous lesions affecting the left hand and forearm, and a patient who presented with subcutaneous abscesses in the left leg. These cases confirm the presence of this type of fungus in Spain. In the second case a combination of amphotericin B lipid complex and posaconazole, together with several surgical resections, were necessary in order to overcome the infection. Copyright © 2013 Revista Iberoamericana de Micología. Published by Elsevier Espana. All rights reserved.

  12. Apparatuses for interaction with a subterranean formation, and methods of use thereof

    DOEpatents

    Clark, Don T.; Jones, Richard L.; Turner, Terry D.; Hubbell, Joel M.; Sisson, James B.

    2007-12-25

    An access casing assembly structured for placement at least partially within a subterranean formation by forcing the access casing assembly thereinto, comprising a plurality of casing sections operably coupled to form a central elongated cavity for providing access to the subterranean region is disclosed. Further, a tip portion of the access casing assembly may include a porous filter through which liquid or gas may communicate with the central elongated cavity. Also, a receiving member or at least one engagement hub may form a portion of the central elongated cavity and may include an engagement feature configured for selectively and lockingly engaging a locking structure of a device to be positioned within the access casing assembly. Methods of use are disclosed. A tensiometer is disclosed including a chamber structured for allowing at least partially filling with a fluid subsequent to contact therewith.

  13. Sarcoid-like cutaneous lesions in chronic adult paracoccidioidomycosis: report of two cases

    PubMed Central

    Fernandes, Nurimar C.; Côrtes, Júlia Gomes; Akitti, Tiyomi; Quintella, Danielle Carvalho; Cuzzi, Tulia

    2017-01-01

    ABSTRACT This study reports two cases of chronic paracoccidioidomycosis with sarcoid-like cutaneous lesions. The patients began the treatment in 2013 at Hospital Universitário Clementino Fraga Filho (HUCFF) of the Universidade Federal do Rio de Janeiro (UFRJ). The first case (mild form) was treated with trimethoprim-sulfamethoxazole (8 mg /kg per day, orally) for three months and, then, with half the dose for nine months; the second (moderate form), with itraconazole (200 mg per day, orally) for 12 months. We point out the rareness of the sarcoid-like cutaneous lesions and the differential diagnoses for other granulomatous diseases. PMID:28591264

  14. Fat embolism syndrome.

    PubMed

    Dhar, Dinesh

    2012-12-01

    Nearly all patients following fractures of bones develop sub-clinical form of fat embolism but the classical form of fat embolism syndrome (FES) presents with triad of respiratory, neurologic and dermal manifestations. Non-traumatic conditions can also have fat embolism, but the incidence is very low. The diagnosis is mainly clinical supported by laboratory and radiological finding. Treatment is mainly supportive with early stabilization of fractured bones. In most cases, prognosis is good if the condition is detected and treated early. High index of suspicion in polytrauma patient is the key to early diagnosis of this condition. This report describes two cases of FES, the second case being fulminant fat embolism with added mortality.

  15. Permission Forms

    ERIC Educational Resources Information Center

    Zirkel, Perry A.

    2005-01-01

    The prevailing practice in public schools is to routinely require permission or release forms for field trips and other activities that pose potential for liability. The legal status of such forms varies, but they are generally considered to be neither rock-solid protection nor legally valueless in terms of immunity. The following case and the…

  16. When Permission Forms Work Best

    ERIC Educational Resources Information Center

    Zirkel, Perry A.

    2005-01-01

    Public schools routinely require permission or release forms for field trips and other activities of potential liability. The legal status of such forms varies, but they are generally considered neither rock-solid protection nor legally valueless in terms of immunity. This article presents a case involving a student who sustained bicycle injuries…

  17. Prediction of Disease Case Severity Level To Determine INA CBGs Rate

    NASA Astrophysics Data System (ADS)

    Puspitorini, Sukma; Kusumadewi, Sri; Rosita, Linda

    2017-03-01

    Indonesian Case-Based Groups (INA CBGs) is case-mix payment system using software grouper application. INA CBGs consisting of four digits code where the last digits indicating the severity level of disease cases. Severity level influence by secondary diagnosis (complications and co-morbidity) related to resource intensity level. It is medical resources used to treat a hospitalized patient. Objectives of this research is developing decision support system to predict severity level of disease cases and illustrate INA CBGs rate by using data mining decision tree classification model. Primary diagnosis (DU), first secondary diagnosis (DS 1), and second secondary diagnosis (DS 2) are attributes that used as input of severity level. The training process using C4.5 algorithm and the rules will represent in the IF-THEN form. Credibility of the system analyzed through testing process and confusion matrix present the results. Outcome of this research shows that first secondary diagnosis influence significant to form severity level predicting rules from new disease cases and INA CBGs rate illustration.

  18. The Effects of Successful versus Failure-Based Cases on Argumentation while Solving Decision-Making Problems

    ERIC Educational Resources Information Center

    Tawfik, Andrew; Jonassen, David

    2013-01-01

    Solving complex, ill-structured problems may be effectively supported by case-based reasoning through case libraries that provide just-in-time domain-specific principles in the form of stories. The cases not only articulate previous experiences of practitioners, but also serve as problem-solving narratives from which learners can acquire meaning.…

  19. Electronic case report forms and electronic data capture within clinical trials and pharmacoepidemiology.

    PubMed

    Rorie, David A; Flynn, Robert W V; Grieve, Kerr; Doney, Alexander; Mackenzie, Isla; MacDonald, Thomas M; Rogers, Amy

    2017-09-01

    Researchers in clinical and pharmacoepidemiology fields have adopted information technology (IT) and electronic data capture, but these remain underused despite the benefits. This review discusses electronic case report forms and electronic data capture, specifically within pharmacoepidemiology and clinical research. The review used PubMed and the Institute of Electrical and Electronic Engineers library. Search terms used were agreed by the authors and documented. PubMed is medical and health based, whereas Institute of Electrical and Electronic Engineers is technology based. The review focuses on electronic case report forms and electronic data capture, but briefly considers other relevant topics; consent, ethics and security. There were 1126 papers found using the search terms. Manual filtering and reviewing of abstracts further condensed this number to 136 relevant manuscripts. The papers were further categorized: 17 contained study data; 40 observational data; 27 anecdotal data; 47 covering methodology or design of systems; one case study; one literature review; two feasibility studies; and one cost analysis. Electronic case report forms, electronic data capture and IT in general are viewed with enthusiasm and are seen as a cost-effective means of improving research efficiency, educating participants and improving trial recruitment, provided concerns about how data will be protected from misuse can be addressed. Clear operational guidelines and best practises are key for healthcare providers, and researchers adopting IT, and further work is needed on improving integration of new technologies with current systems. A robust method of evaluation for technical innovation is required. © 2017 The Authors. British Journal of Clinical Pharmacology published by John Wiley & Sons Ltd on behalf of British Pharmacological Society.

  20. Electronic case report forms and electronic data capture within clinical trials and pharmacoepidemiology

    PubMed Central

    Flynn, Robert W. V.; Grieve, Kerr; Doney, Alexander; Mackenzie, Isla; MacDonald, Thomas M.; Rogers, Amy

    2017-01-01

    Aims Researchers in clinical and pharmacoepidemiology fields have adopted information technology (IT) and electronic data capture, but these remain underused despite the benefits. This review discusses electronic case report forms and electronic data capture, specifically within pharmacoepidemiology and clinical research. Methods The review used PubMed and the Institute of Electrical and Electronic Engineers library. Search terms used were agreed by the authors and documented. PubMed is medical and health based, whereas Institute of Electrical and Electronic Engineers is technology based. The review focuses on electronic case report forms and electronic data capture, but briefly considers other relevant topics; consent, ethics and security. Results There were 1126 papers found using the search terms. Manual filtering and reviewing of abstracts further condensed this number to 136 relevant manuscripts. The papers were further categorized: 17 contained study data; 40 observational data; 27 anecdotal data; 47 covering methodology or design of systems; one case study; one literature review; two feasibility studies; and one cost analysis. Conclusion Electronic case report forms, electronic data capture and IT in general are viewed with enthusiasm and are seen as a cost‐effective means of improving research efficiency, educating participants and improving trial recruitment, provided concerns about how data will be protected from misuse can be addressed. Clear operational guidelines and best practises are key for healthcare providers, and researchers adopting IT, and further work is needed on improving integration of new technologies with current systems. A robust method of evaluation for technical innovation is required. PMID:28276585

  1. Comparison of hydrocephalus appearance at spinaldysraphia.

    PubMed

    Elshani, Besnik; Lenjani, Basri

    2013-01-01

    Congenital malformation of spinal dysraphism followed by hydrocephalus are phenomenon reveals during intrauterine child growth. Prime objective of this work was to present Comparison of hydrocephalus appearance at spinal dysraphism respectively at its meningocele and myelomeningocele forms in Neurosurgery Clinic in UCC in Prishtina. It is perfected with retrospective and prospective method precisely of its epidemiologic part summarizing notices from patients' histories which in 2000-2006 are hospitalized in Neurosurgery Clinic from (QFLPK)--Pediatric Clinic and Children Box (Department)--Gynecology Clinic and from Sanitary Regional Center throughout Kosova. Our study objects were two groups, as the first group 90 patients with spinal dysraphism where neurosurgery operations were done and classified types of dysraphism. At myelomeningocele hydrocephalus has dominated and in a percent of appearance and as acute of its active form was 97% of hydrocephalus form where subjected to cerebrospinal liquid derivation with ventriculo -peritoneal shunt in comparison with meningocele we do not have involvation of spinal nerve element, hydrocephalus takes active form with intervention indication in 60% of cases. Reflection in shown deficit aspect is totally different at myelomeningoceles where lower paraplegia dominate more than paraparesis. The second patient operative technique developed by hydrocephalus with neurosurgical intervention indication has to do with placing of (VP) ventriculo- peritoneal system (shant) at myelomeningoceles with hydrocephalus 58 cases and 12 cases meningoceles with hydrocephalus. Post operative meningitis (shant meningitis): from 70 operated cases of hydrocephalus with spinal dysraphism shunts complications from all types are just cases. Finally that appearance of hydrocephalus compared at spinal dysraphism dominate at myellomeningoceles as in notice time aspect, it is persisting and further acute, with vital motivation for neurosurgical intervention.

  2. [Nonsurgical and surgical treatment of an urachal fistula in an alpaca cria. A case report].

    PubMed

    Kubus, K; Wöckel, A; Felton, C; Schwarzenberger, J; Sobiraj, A

    2015-01-01

    Urachal fistula is a neonatal condition. There are two reported forms: a congenital and an acquired form. We describe the case of a 6-hour-old female alpaca cria that was presented with a damp umbilicus and a meconium impaction. Conservative treatment of the urachal fistula with local and systemic medication was unsuccessful after 6 days; therefore, a resection of the umbilicus under general anaesthesia was performed. Reconvalescence was uneventful.

  3. Supergravity backgrounds for deformations of AdS n × S n supercoset string models

    DOE PAGES

    Lunin, O.; Roiban, R.; Tseytlin, A. A.

    2014-12-11

    We considermore » type IIB supergravity backgrounds corresponding to the deformed AdS n × S n × T 10 - 2 n supercoset string models of the type constructed in arXiv:1309.5850[2] which depend on one deformation parameter κ. In AdS 2 × S 2 case we find that the deformed metric can be extended to a full supergravity solution with non-trivial dilaton, RR scalar and RR 5-form strength. The solution depends on a free parameter a that should be chosen as a particular function of κ to correspond to the deformed supercoset model. In AdS 3 × S 3 case the full solution supported by the dilaton, RR scalar and RR 3-form strength exists only in the two special cases, a = 0 and a = 1 . We conjecture that there may be a more general one-parameter solution supported by several RR fields that for particular a = a ( κ ) corresponds to the supercoset model. In the most complicated deformed AdS 5 × S 5 case we were able to find only the expressions for the dilaton and the RR scalar. The full solution is likely to be supported by a combination of the 5-form and 3-form field strengths. We comment on the singularity structure of the resulting metric and exact dilaton field.« less

  4. Supergravity backgrounds for deformations of AdS n × S n supercoset string models

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lunin, O.; Roiban, R.; Tseytlin, A. A.

    We considermore » type IIB supergravity backgrounds corresponding to the deformed AdS n × S n × T 10 - 2 n supercoset string models of the type constructed in arXiv:1309.5850[2] which depend on one deformation parameter κ. In AdS 2 × S 2 case we find that the deformed metric can be extended to a full supergravity solution with non-trivial dilaton, RR scalar and RR 5-form strength. The solution depends on a free parameter a that should be chosen as a particular function of κ to correspond to the deformed supercoset model. In AdS 3 × S 3 case the full solution supported by the dilaton, RR scalar and RR 3-form strength exists only in the two special cases, a = 0 and a = 1 . We conjecture that there may be a more general one-parameter solution supported by several RR fields that for particular a = a ( κ ) corresponds to the supercoset model. In the most complicated deformed AdS 5 × S 5 case we were able to find only the expressions for the dilaton and the RR scalar. The full solution is likely to be supported by a combination of the 5-form and 3-form field strengths. We comment on the singularity structure of the resulting metric and exact dilaton field.« less

  5. Primary Spinal Intramedullary Neurocysticercosis: A Report of 3 Cases.

    PubMed

    Datta, Subramanya G S; Mehta, Ritu; Macha, Shrikant; Tripathi, Sanjog

    2017-09-01

    We describe a series of 3 cases of the rare intramedullary form of primary spinal neurocysticercosis. The cases were seen in varied age groups and showed different profiles at presentation. All the cases were thoroughly evaluated clinically and radiologically. Serologic tests were not conducted. In all cases, magnetic resonance imaging showed a large intramedullary lesion in the thoracic spinal cord consisting of a cystic lesion with a well-defined intramural nodule. One case was managed with steroids and cysticidal therapy, a second case was managed with steroids and surgery (2 emergency procedures), while the third case was managed without any medical or surgical intervention, as the patient was unwilling for either. All cases showed good neurologic recovery. In the second case where surgery was done, histologic examination of the resected specimen demonstrated the cysticercal parasite surrounded by mixed inflammatory infiltrate. As there were no intracranial lesions in all 3 cases, the final diagnosis was primary isolated intramedullary neurocysticercosis. Primary isolated intramedullary-neurocysticercosis remains a rare condition afflicting the spinal cord. It forms a small subset of cysticercal infestation of the neuraxis. Such evidence is rare, and only anecdotal reports are available. Our case series captures the wide spectrum of presentations, as well as the management options, and highlights the varied ways in which these cases were managed. Copyright © 2017 Elsevier Inc. All rights reserved.

  6. Morbidity of mansoni schistosomiasis in Pernambuco-Brazil: Analysis on the temporal evolution of deaths, hospital admissions and severe clinical forms (1999-2014).

    PubMed

    Barbosa, Constança Simões; de Souza Gomes, Elainne Christine; Campos, Julyana Viegas; de Oliveira, Fernando José Moreira; da Silva Mesquita, Millena Carla; de Oliveira, Emilia Carolle Azevedo; Domingues, Ana Lucia Coutinho

    2016-12-01

    Current scientific information reported that due to successive treatments of schistosomiasis cases in endemic areas of Brazil in the last 30 years, there has been a decrease in severe clinical form (hepatosplenic) and mortality from upper gastrointestinal bleeding due to this disease. Against this information, literature data show that the state of Pernambuco presents significant percentage of deaths and hospitalizations due to schistosomiasis, and occurrence of severe clinical forms as schistosomiasis myeloradiculopathy and persistence of localities with high parasite loads. This scenario justified this research which seeking to update the morbidity and mortality of schistosomiasis in Pernambuco. To conduct a temporal analysis on the evolution of deaths, hospital admissions and severe forms of Manson's schistosomiasis over the last 16 years in Pernambuco, Brazil. It was performed a gathering secondary data on schistosomiasis, from healthcare information systems and from the records of Hospital das Clínicas, Federal University of Pernambuco (HC-UFPE), covering the period from 1999 to 2014. From 1999 to 2013 were registred 2578 deaths due to schistosomiasis and between 2008 and 2014 were recorded 473 hospitalizations for this disease. Among 1999-2014 were identified 1943 cases of schistosomiasis treated at the Hospital das Clínicas of Pernambuco. Among these cases, 72.6% (n. 1411) of the individuals presented the hepatosplenic clinical form (HE), 60.8% (n. 858) were at the age group 30-59 years (adults) and 58% were female. Among the HE cases, 4.6% (n. 58) had ascites, 43.2% (n. 556) had upper gastrointestinal bleeding and 39.1% (n. 489) had collateral circulation. The pattern of fibrosis in the liver E/EC (advanced fibrosis) and F/FC (very advanced fibrosis) occurred in 65.5% (n. 793) of cases. Between 1999-2014 the evolution curve of severe clinical forms of schistosomiasis remained stable, showing a tendency to decline from 2012. When compared to other states of Brazil, Pernambuco shows high numbers of deaths and hospital admissions due to schistosomiasis. The actions of the Schistosomiasis Control Program (PCE) have been developed in a disintegrated, disjointed and discontinuous way, which may explain the magnitude of deaths, hospitalizations and severe forms of the disease in Pernambuco, showing a lack of control and the maintenance of severe frame morbidity of schistosomiasis in this state. Copyright © 2016 Elsevier B.V. All rights reserved.

  7. Genetics Home Reference: paroxysmal nocturnal hemoglobinuria

    MedlinePlus

    ... at increased risk of developing cancer in blood-forming cells (leukemia). In some cases, people who have ... mutations of the PIGA gene occur in blood-forming cells called hematopoietic stem cells, which are found ...

  8. Cooperation or Separation?--Part 1

    ERIC Educational Resources Information Center

    Rowan, Patricia

    1977-01-01

    Describes one of the first examples in the Inner London Education Authority of how cooperation between sixth forms might be made to work, in this case the successful sixth-form center in Tower Hamlets. (Author/RK)

  9. Algebra of implicitly defined constraints for gravity as the general form of embedding theory

    NASA Astrophysics Data System (ADS)

    Paston, S. A.; Semenova, E. N.; Franke, V. A.; Sheykin, A. A.

    2017-01-01

    We consider the embedding theory, the approach to gravity proposed by Regge and Teitelboim, in which 4D space-time is treated as a surface in high-dimensional flat ambient space. In its general form, which does not contain artificially imposed constraints, this theory can be viewed as an extension of GR. In the present paper we study the canonical description of the embedding theory in this general form. In this case, one of the natural constraints cannot be written explicitly, in contrast to the case where additional Einsteinian constraints are imposed. Nevertheless, it is possible to calculate all Poisson brackets with this constraint. We prove that the algebra of four emerging constraints is closed, i.e., all of them are first-class constraints. The explicit form of this algebra is also obtained.

  10. Short form of Demodex species mite in the dog: occurrence and measurements.

    PubMed

    Chesney, C J

    1999-02-01

    A form of Demodex species mite shorter in length than Demodex canis was found in six consecutive cases of canine demodicosis. The mean length of the parasite was 122.6 microns (SD 12.0 microns, 39 mites counted), significantly shorter than either male or female forms of D canis (P < 0.0001). The proportion of short to long mites in each case varied from 0.5 to 22 per 100. In young dogs, skin signs associated with the presence of mites were first noted after about seven months, while in the oldest subject the disease became apparent at 10 years of age. This form of mite has now been found in four countries over three continents, the findings suggesting that it is not uncommon and is acquired in puppyhood, although it may be carried unnoticed for many years.

  11. How novice, skilled and advanced clinical researchers include variables in a case report form for clinical research: a qualitative study

    PubMed Central

    Chu, Hongling; Zeng, Lin; Fetters, Micheal D; Li, Nan; Tao, Liyuan; Shi, Yanyan; Zhang, Hua; Wang, Xiaoxiao; Li, Fengwei; Zhao, Yiming

    2017-01-01

    Objectives Despite varying degrees in research training, most academic clinicians are expected to conduct clinical research. The objective of this research was to understand how clinical researchers of different skill levels include variables in a case report form for their clinical research. Setting The setting for this research was a major academic institution in Beijing, China. Participants The target population was clinical researchers with three levels of experience, namely, limited clinical research experience, clinicians with rich clinical research experience and clinical research experts. Methods Using a qualitative approach, we conducted 13 individual interviews (face to face) and one group interview (n=4) with clinical researchers from June to September 2016. Based on maximum variation sampling to identify researchers with three levels of research experience: eight clinicians with limited clinical research experience, five clinicians with rich clinical research experience and four clinical research experts. These 17 researchers had diverse hospital-based medical specialties and or specialisation in clinical research. Results Our analysis yields a typology of three processes developing a case report form that varies according to research experience level. Novice clinician researchers often have an incomplete protocol or none at all, and conduct data collection and publication based on a general framework. Experienced clinician researchers include variables in the case report form based on previous experience with attention to including domains or items at risk for omission and by eliminating unnecessary variables. Expert researchers consider comprehensively in advance data collection and implementation needs and plan accordingly. Conclusion These results illustrate increasing levels of sophistication in research planning that increase sophistication in selection for variables in the case report form. These findings suggest that novice and intermediate-level researchers could benefit by emulating the comprehensive planning procedures such as those used by expert clinical researchers. PMID:28928184

  12. How novice, skilled and advanced clinical researchers include variables in a case report form for clinical research: a qualitative study.

    PubMed

    Chu, Hongling; Zeng, Lin; Fetters, Micheal D; Li, Nan; Tao, Liyuan; Shi, Yanyan; Zhang, Hua; Wang, Xiaoxiao; Li, Fengwei; Zhao, Yiming

    2017-09-18

    Despite varying degrees in research training, most academic clinicians are expected to conduct clinical research. The objective of this research was to understand how clinical researchers of different skill levels include variables in a case report form for their clinical research. The setting for this research was a major academic institution in Beijing, China. The target population was clinical researchers with three levels of experience, namely, limited clinical research experience, clinicians with rich clinical research experience and clinical research experts. Using a qualitative approach, we conducted 13 individual interviews (face to face) and one group interview (n=4) with clinical researchers from June to September 2016. Based on maximum variation sampling to identify researchers with three levels of research experience: eight clinicians with limited clinical research experience, five clinicians with rich clinical research experience and four clinical research experts. These 17 researchers had diverse hospital-based medical specialties and or specialisation in clinical research. Our analysis yields a typology of three processes developing a case report form that varies according to research experience level. Novice clinician researchers often have an incomplete protocol or none at all, and conduct data collection and publication based on a general framework. Experienced clinician researchers include variables in the case report form based on previous experience with attention to including domains or items at risk for omission and by eliminating unnecessary variables. Expert researchers consider comprehensively in advance data collection and implementation needs and plan accordingly. These results illustrate increasing levels of sophistication in research planning that increase sophistication in selection for variables in the case report form. These findings suggest that novice and intermediate-level researchers could benefit by emulating the comprehensive planning procedures such as those used by expert clinical researchers. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  13. Diclofenac Salts. V. Examples of Polymorphism among Diclofenac Salts with Alkyl-hydroxy Amines Studied by DSC and HSM

    PubMed Central

    Fini, Adamo; Cavallari, Cristina; Ospitali, Francesca

    2010-01-01

    Nine diclofenac salts prepared with alkyl-hydroxy amines were analyzed for their properties to form polymorphs by DSC and HSM techniques. Thermograms of the forms prepared from water or acetone are different in most cases, suggesting frequent examples of polymorphism among these salts. Polymorph transition can be better highlighted when analysis is carried out by thermo-microscopy, which in most cases made it possible to observe the processes of melting of the metastable form and re-crystallization of the stable one. Solubility values were qualitatively related to the crystal structure of the salts and the molecular structure of the cation. PMID:27721347

  14. Finite elements and finite differences for transonic flow calculations

    NASA Technical Reports Server (NTRS)

    Hafez, M. M.; Murman, E. M.; Wellford, L. C.

    1978-01-01

    The paper reviews the chief finite difference and finite element techniques used for numerical solution of nonlinear mixed elliptic-hyperbolic equations governing transonic flow. The forms of the governing equations for unsteady two-dimensional transonic flow considered are the Euler equation, the full potential equation in both conservative and nonconservative form, the transonic small-disturbance equation in both conservative and nonconservative form, and the hodograph equations for the small-disturbance case and the full-potential case. Finite difference methods considered include time-dependent methods, relaxation methods, semidirect methods, and hybrid methods. Finite element methods include finite element Lax-Wendroff schemes, implicit Galerkin method, mixed variational principles, dual iterative procedures, optimal control methods and least squares.

  15. Vitrectomy for epiretinal membrane in adult-onset Coats' disease.

    PubMed

    Kumar, Pradeep; Kumar, Vinod

    2017-10-01

    Coats' disease is characterized by retinal vascular telangiectasia and subretinal and intraretinal exudation. A relatively benign form of the disease that occurs in adults is referred to as adult-onset Coats' disease. Involvement of macula in the form of macular edema and exudation are the common presenting features in both forms of the disease. We describe a rare case of adult-onset Coats' disease that presented with epiretinal membrane (ERM). Laser photocoagulation of retinal vascular telangiectasia resulted in worsening of patient's symptoms and ERM. Early pars plana vitrectomy resulted in resolution of the patient's symptoms. Utility of ultra-wide-field imaging and rationale of early vitrectomy in such cases are discussed.

  16. Vitrectomy for epiretinal membrane in adult-onset Coats’ disease

    PubMed Central

    Kumar, Pradeep; Kumar, Vinod

    2017-01-01

    Coats’ disease is characterized by retinal vascular telangiectasia and subretinal and intraretinal exudation. A relatively benign form of the disease that occurs in adults is referred to as adult-onset Coats’ disease. Involvement of macula in the form of macular edema and exudation are the common presenting features in both forms of the disease. We describe a rare case of adult-onset Coats’ disease that presented with epiretinal membrane (ERM). Laser photocoagulation of retinal vascular telangiectasia resulted in worsening of patient's symptoms and ERM. Early pars plana vitrectomy resulted in resolution of the patient's symptoms. Utility of ultra-wide-field imaging and rationale of early vitrectomy in such cases are discussed. PMID:29044085

  17. Current-sheet formation in two-dimensional coronal fields

    NASA Astrophysics Data System (ADS)

    Billinghurst, M. N.; Craig, I. J. D.; Sneyd, A. D.

    1993-11-01

    The formation of current sheets by shearing motions in line-tied twin-lobed fields is examined. A general analytic argument shows that current sheets form along the fieldline bounding the two lobes in the case of both symmetric and asymmetric footpoint motions. In the case of strictly antisymmetric motions however no current sheets can form. These findings are reinforced by magnetic relaxation experiments involving sheared two-lobed fields represented by Clebsh variables. It is pointed out that, although current singularites cannot be expected to form when the line-tying assumption is relaxed, the two-lobed geometry is still consistent with the formation of highly localised currents - and strong resistive dissipation - along field lines close to the bounding fieldline.

  18. Apparatus for forming adobe bricks and drilling wells

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kinnamon, H. D.

    1985-02-12

    An improved apparatus for the continuous and relatively labor-free fabrication of adobe bricks and the forcing of well casings into the earth. With regard to forming adobe bricks, a rotating table carries the bricks being processed from one station to the next and a novel means for applying unusually high forming pressures permits immediate forming and ejection of the bricks from the forms while at the same time producing adobe bricks of improved quality and hardness characteristics.

  19. Heavy quark form factors at two loops

    NASA Astrophysics Data System (ADS)

    Ablinger, J.; Behring, A.; Blümlein, J.; Falcioni, G.; De Freitas, A.; Marquard, P.; Rana, N.; Schneider, C.

    2018-05-01

    We compute the two-loop QCD corrections to the heavy quark form factors in the case of the vector, axial-vector, scalar and pseudoscalar currents up to second order in the dimensional parameter ɛ =(4 -D )/2 . These terms are required in the renormalization of the higher-order corrections to these form factors.

  20. 47 CFR 1.2107 - Submission of down payment and filing of long-form applications.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...-form applications. 1.2107 Section 1.2107 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL... payment and filing of long-form applications. (a) After bidding has ended, the Commission will identify... remaining balance due on the license or authorization, in which case it will not be returned, or until the...

  1. Separability of Item and Person Parameters in Response Time Models.

    ERIC Educational Resources Information Center

    Van Breukelen, Gerard J. P.

    1997-01-01

    Discusses two forms of separability of item and person parameters in the context of response time models. The first is "separate sufficiency," and the second is "ranking independence." For each form a theorem stating sufficient conditions is proved. The two forms are shown to include several cases of models from psychometric…

  2. The Synchrony and Diachrony of Bosnian-Croatian-Serbian Adjectival Long-Form Allomorphy (ALFA)

    ERIC Educational Resources Information Center

    Pennington, James Joshua

    2010-01-01

    In Bosnian-Croatian-Serbian (BCS), the gentive (G) and dative/locative (DL) cases exhibit adjectival long-form allomorphy (ALFA). The genitive -"og" -"oga" and the DL -"om" -"ome" -"omu" stand in free variation, inasmuch as when one form is substituted for another the truth value of an utterance…

  3. Symmetric and antisymmetric forms of the Pauli master equation

    PubMed Central

    Klimenko, A. Y.

    2016-01-01

    When applied to matter and antimatter states, the Pauli master equation (PME) may have two forms: time-symmetric, which is conventional, and time-antisymmetric, which is suggested in the present work. The symmetric and antisymmetric forms correspond to symmetric and antisymmetric extensions of thermodynamics from matter to antimatter — this is demonstrated by proving the corresponding H-theorem. The two forms are based on the thermodynamic similarity of matter and antimatter and differ only in the directions of thermodynamic time for matter and antimatter (the same in the time-symmetric case and the opposite in the time-antisymmetric case). We demonstrate that, while the symmetric form of PME predicts an equibalance between matter and antimatter, the antisymmetric form of PME favours full conversion of antimatter into matter. At this stage, it is impossible to make an experimentally justified choice in favour of the symmetric or antisymmetric versions of thermodynamics since we have no experience of thermodynamic properties of macroscopic objects made of antimatter, but experiments of this kind may become possible in the future. PMID:27440454

  4. TRASYS form factor matrix normalization

    NASA Technical Reports Server (NTRS)

    Tsuyuki, Glenn T.

    1992-01-01

    A method has been developed for adjusting a TRASYS enclosure form factor matrix to unity. This approach is not limited to closed geometries, and in fact, it is primarily intended for use with open geometries. The purpose of this approach is to prevent optimistic form factors to space. In this method, nodal form factor sums are calculated within 0.05 of unity using TRASYS, although deviations as large as 0.10 may be acceptable, and then, a process is employed to distribute the difference amongst the nodes. A specific example has been analyzed with this method, and a comparison was performed with a standard approach for calculating radiation conductors. In this comparison, hot and cold case temperatures were determined. Exterior nodes exhibited temperature differences as large as 7 C and 3 C for the hot and cold cases, respectively when compared with the standard approach, while interior nodes demonstrated temperature differences from 0 C to 5 C. These results indicate that temperature predictions can be artificially biased if the form factor computation error is lumped into the individual form factors to space.

  5. The Trade-Offs of Developing a Case Management Model for Chronically Mentally Ill People.

    ERIC Educational Resources Information Center

    Belcher, John R.

    1993-01-01

    Addresses role of case management in care of chronically mentally ill persons. Notes that case management can be effective if designed so that services match client needs and service costs are measured accurately. Contends that profit-maximizing nature of U.S. health care system makes some form of capitation likely in design of case management…

  6. Case Report Writing in a Doctor of Physical Therapy Education Program: A Case Study

    ERIC Educational Resources Information Center

    Fillyaw, Michael J.

    2011-01-01

    Case reports are an established form of scholarship used for teaching and learning in medicine and health care, but there are few examples of the teaching and learning activities used to prepare students to write a case report. This report describes the implementation of two courses that prepare physical therapy students to write and disseminate a…

  7. Gleason grade 4 prostate adenocarcinoma patterns: an interobserver agreement study among genitourinary pathologists.

    PubMed

    Kweldam, Charlotte F; Nieboer, Daan; Algaba, Ferran; Amin, Mahul B; Berney, Dan M; Billis, Athanase; Bostwick, David G; Bubendorf, Lukas; Cheng, Liang; Compérat, Eva; Delahunt, Brett; Egevad, Lars; Evans, Andrew J; Hansel, Donna E; Humphrey, Peter A; Kristiansen, Glen; van der Kwast, Theodorus H; Magi-Galluzzi, Cristina; Montironi, Rodolfo; Netto, George J; Samaratunga, Hemamali; Srigley, John R; Tan, Puay H; Varma, Murali; Zhou, Ming; van Leenders, Geert J L H

    2016-09-01

    To assess the interobserver reproducibility of individual Gleason grade 4 growth patterns. Twenty-three genitourinary pathologists participated in the evaluation of 60 selected high-magnification photographs. The selection included 10 cases of Gleason grade 3, 40 of Gleason grade 4 (10 per growth pattern), and 10 of Gleason grade 5. Participants were asked to select a single predominant Gleason grade per case (3, 4, or 5), and to indicate the predominant Gleason grade 4 growth pattern, if present. 'Consensus' was defined as at least 80% agreement, and 'favoured' as 60-80% agreement. Consensus on Gleason grading was reached in 47 of 60 (78%) cases, 35 of which were assigned to grade 4. In the 13 non-consensus cases, ill-formed (6/13, 46%) and fused (7/13, 54%) patterns were involved in the disagreement. Among the 20 cases where at least one pathologist assigned the ill-formed growth pattern, none (0%, 0/20) reached consensus. Consensus for fused, cribriform and glomeruloid glands was reached in 2%, 23% and 38% of cases, respectively. In nine of 35 (26%) consensus Gleason grade 4 cases, participants disagreed on the growth pattern. Six of these were characterized by large epithelial proliferations with delicate intervening fibrovascular cores, which were alternatively given the designation fused or cribriform growth pattern ('complex fused'). Consensus on Gleason grade 4 growth pattern was predominantly reached on cribriform and glomeruloid patterns, but rarely on ill-formed and fused glands. The complex fused glands seem to constitute a borderline pattern of unknown prognostic significance on which a consensus could not be reached. © 2016 John Wiley & Sons Ltd.

  8. Somatic mosaicism in a case of apparently sporadic Creutzfeldt-Jakob disease carrying a de novo D178N mutation in the PRNP gene.

    PubMed

    Alzualde, A; Moreno, F; Martínez-Lage, P; Ferrer, I; Gorostidi, A; Otaegui, D; Blázquez, L; Atares, B; Cardoso, S; Martínez de Pancorbo, M; Juste, R; Rodríguez-Martínez, A B; Indakoetxea, B; López de Munain, A

    2010-10-05

    Transmissible spongiform encephalopathies (TSEs) are a group of rare fatal neurodegenerative disorders. Creutzfeldt-Jakob disease (CJD) represents the most common form of TSE and can be classified into sporadic, genetic, iatrogenic and variant forms. Genetic cases are related to prion protein gene mutations but they only account for 10-20% of cases. Here we report an apparently sporadic CJD case with negative family history carrying a mutation at codon 178 of prion protein gene. This mutation is a de novo mutation as the parents of the case do not show it. Furthermore the presence of three different alleles (wild type 129M-178D and 129V-178D and mutated 129V-178N), confirmed by different methods, indicates that this de novo mutation is a post-zygotic mutation that produces somatic mosaicism. The proportion of mutated cells in peripheral blood cells and in brain tissue was similar and was estimated at approximately 97%, suggesting that the mutation occurred at an early stage of embryogenesis. Neuropathological examination disclosed spongiform change mainly involving the caudate and putamen, and the cerebral cortex, together with proteinase K-resistant PrP globular deposits in the cerebrum and cerebellum. PrP typing was characterized by a lower band of 21 kDa. This is the first case of mosaicism described in prion diseases and illustrates a potential etiology for apparently sporadic neurodegenerative diseases. In light of this case, genetic counseling for inherited and sporadic forms of transmissible encephalopathies should take into account this possibility for genetic screening procedures.

  9. Lexical enhancement during prime-target integration: ERP evidence from matched-case identity priming.

    PubMed

    Vergara-Martínez, Marta; Gómez, Pablo; Jiménez, María; Perea, Manuel

    2015-06-01

    A number of experiments have revealed that matched-case identity PRIME-TARGET pairs are responded to faster than mismatched-case identity prime-TARGET pairs for pseudowords (e.g., JUDPE-JUDPE < judpe-JUDPE), but not for words (JUDGE-JUDGE = judge-JUDGE). These findings suggest that prime-target integration processes are enhanced when the stimuli tap onto lexical representations, overriding physical differences between the stimuli (e.g., case). To track the time course of this phenomenon, we conducted an event-related potential (ERP) masked-priming lexical decision experiment that manipulated matched versus mismatched case identity in words and pseudowords. The behavioral results replicated previous research. The ERP waves revealed that matched-case identity-priming effects were found at a very early time epoch (N/P150 effects) for words and pseudowords. Importantly, around 200 ms after target onset (N250), these differences disappeared for words but not for pseudowords. These findings suggest that different-case word forms (lower- and uppercase) tap into the same abstract representation, leading to prime-target integration very early in processing. In contrast, different-case pseudoword forms are processed as two different representations. This word-pseudoword dissociation has important implications for neural accounts of visual-word recognition.

  10. 77 FR 56714 - Agency Information Collection (Statement of Accredited Representative in Appealed Case...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-13

    ... Representative in Appealed Case, VA Form 646. OMB Control Number: 2900-0042. Type of Review: Extension of a... (Statement of Accredited Representative in Appealed Case) Activities Under OMB Review AGENCY: Board of Veterans' Appeals, Department of Veterans Affairs. ACTION: Notice. SUMMARY: In compliance with the...

  11. 29 CFR 1904.11 - Recording criteria for work-related tuberculosis cases.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 5 2010-07-01 2010-07-01 false Recording criteria for work-related tuberculosis cases... Forms and Recording Criteria § 1904.11 Recording criteria for work-related tuberculosis cases. (a) Basic... tuberculosis (TB), and that employee subsequently develops a tuberculosis infection, as evidenced by a positive...

  12. 75 FR 65355 - Agency Forms Undergoing Paperwork Reduction Act Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-22

    ... Project Case Studies of Communities and States Funded under Community Activities under the Communities..., system, and environmental changes. Intensive case studies will be conducted with 24 sites: Six ARRA... Act. The case study sites will be selected to include a mix of State or community characteristics...

  13. 29 CFR 1904.11 - Recording criteria for work-related tuberculosis cases.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 5 2013-07-01 2013-07-01 false Recording criteria for work-related tuberculosis cases... Forms and Recording Criteria § 1904.11 Recording criteria for work-related tuberculosis cases. (a) Basic... tuberculosis (TB), and that employee subsequently develops a tuberculosis infection, as evidenced by a positive...

  14. 29 CFR 1904.11 - Recording criteria for work-related tuberculosis cases.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 5 2012-07-01 2012-07-01 false Recording criteria for work-related tuberculosis cases... Forms and Recording Criteria § 1904.11 Recording criteria for work-related tuberculosis cases. (a) Basic... tuberculosis (TB), and that employee subsequently develops a tuberculosis infection, as evidenced by a positive...

  15. 29 CFR 1904.11 - Recording criteria for work-related tuberculosis cases.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 5 2014-07-01 2014-07-01 false Recording criteria for work-related tuberculosis cases... Forms and Recording Criteria § 1904.11 Recording criteria for work-related tuberculosis cases. (a) Basic... tuberculosis (TB), and that employee subsequently develops a tuberculosis infection, as evidenced by a positive...

  16. 29 CFR 1904.11 - Recording criteria for work-related tuberculosis cases.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 5 2011-07-01 2011-07-01 false Recording criteria for work-related tuberculosis cases... Forms and Recording Criteria § 1904.11 Recording criteria for work-related tuberculosis cases. (a) Basic... tuberculosis (TB), and that employee subsequently develops a tuberculosis infection, as evidenced by a positive...

  17. A Rare Case of FAP in Kashmir Valley.

    PubMed

    Sameer, A Syed; Pandith, Arshad A; Syeed, Nidda; Siddiqi, Mushtaq A; Chowdri, Nissar A

    2011-06-01

    Familial adenomatous polyposis (FAP) is the commonest form of inherited form of CRC. It comprises of about 5% of all the colorectal cancers (CRCs). FAP patients have a family history of CRC that suggests a genetic contribution, common exposures among family members, or a combination of both. This case report gives a glimpse of the phenotypic manifestation of FAP and the underlying molecular mechanism which leads to FAP, in addition it also sheds a light on the management of FAP in early stages of life.

  18. Infography use to requirements specification for the design of the building

    NASA Astrophysics Data System (ADS)

    Losev, Konstantin; Sinenko, Sergey

    2017-10-01

    The study contributes to a growing body of research Transport infrastructure in a construction object life cycle management and presents areas in which further investigation is needed. The object of study are Railway buildings and structures and the Employer’s information requirements (EIR) for design of individual residential building. The task of the study was to determine necessary and sufficient scope of parameters which contained in inforaphic form of EIR comparing with traditional text form of EIR. Also, the task was to determine what categories of the traditional EIR are transferred to an infographic representation form and what categories are ignored in case of a relatively low complexity building. Methods that have been used in the study were infographical representation of text and further expert evaluation. Conclusions of the study present the necessary and sufficient scope of parameters for inforaphic form of EIR, the relations between infographic parameters and categories of the EIR traditional form and subcategories of the traditional EIR that are ignored in case of a relatively low complexity building.

  19. 32 CFR 881.8 - Disposition of documents.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... documents. (a) File a copy of the application, supporting evidence, and DD Form 214 in the Master Personnel... cases. Send copies of DD Form 214 to: (1) The applicant. (2) The Veterans' Administration. (3) HQ AFPC...

  20. 32 CFR 644.70 - Closing of cases.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... made before satisfaction of all tax liens. The tax receipt should be forwarded to HQDA (DAEN-REP-S... Department of the Treasury Form and completed ENG Forms 1569 and 1571. (x) Certified copy of any waiver...

  1. 32 CFR 644.70 - Closing of cases.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... made before satisfaction of all tax liens. The tax receipt should be forwarded to HQDA (DAEN-REP-S... Department of the Treasury Form and completed ENG Forms 1569 and 1571. (x) Certified copy of any waiver...

  2. 32 CFR 644.70 - Closing of cases.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... made before satisfaction of all tax liens. The tax receipt should be forwarded to HQDA (DAEN-REP-S... Department of the Treasury Form and completed ENG Forms 1569 and 1571. (x) Certified copy of any waiver...

  3. 32 CFR 644.70 - Closing of cases.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... made before satisfaction of all tax liens. The tax receipt should be forwarded to HQDA (DAEN-REP-S... Department of the Treasury Form and completed ENG Forms 1569 and 1571. (x) Certified copy of any waiver...

  4. Asbestos bodies and the diagnosis of asbestosis in chrysotile workers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Holden, J.; Churg, A.

    1986-01-01

    It has been suggested that because chrysotile asbestos forms asbestos bodies poorly, use of the traditional histologic requirements (diffuse interstitial fibrosis plus asbestos bodies) for the diagnosis of asbestosis, may lead to an underdiagnosis of this condition in workers exposed only to chrysotile. Lungs from 25 chrysotile miners with diffuse interstitial fibrosis were examined. Asbestos bodies were found easily in histologic section using hematoxylin and eosin stains in all cases. Mineralogic analysis of four cases showed that 46 of 72 (64%) bodies isolated and examined contained chrysotile cores, and 21 of 72 (29%) bodies contained cores of the amphiboles tremolitemore » and actinolite. By contrast, tremolite and actinolite constituted the majority of uncoated fibers in these cases. The mean length for bodies formed on chrysotile was 35 ..mu..m, and for bodies formed on tremolite or actinolite, 36 ..mu..m. The authors conclude that (1) the usual histologic criteria for the diagnosis of asbestos are applicable to chrysotile-exposed workers; (2) in workers with occupational chrysotile exposure, bodies form readily on this mineral; and (3) asbestos bodies in these lungs reflect the presence of long asbestos fibers.« less

  5. Completeness of tuberculosis reporting forms for disease control in individuals with HIV/AIDS in priority cities of Bahia state.

    PubMed

    Lírio, Monique; dos Santos, Normeide Pedreira; Passos, Louran Andrade Reis; Kritski, Afrânio; Galvão-Castro, Bernardo; Grassi, Maria Fernanda Rios

    2015-04-01

    The control of HIV / Tuberculosis (TB) co -infection remains a challenge for public health. Notification is mandatory for both diseases and the National Case Registry Database (Sinan) is responsible for the collection and processing of individual forms of reporting and monitoring. The adequate fulfillment of these fields chips (completeness) is essential to follow the dynamics of the disease and set priorities for intervention. The aim of this study was to evaluate the completeness of the notification forms of tuberculosis in the priority municipalities of Bahia (Camaçari , Feira de Santana , Ilhéus , Itabuna, Jequié, Lauro de Freitas , Porto Seguro , Teixeira de Freitas , Paulo Afonso, Barreiras and Salvador) to control the disease in individuals with HIV/AIDS using tabulations obtained from the Sinan in the period from 2001 to 2010. The results showed that despite the completeness of the field HIV be above 50 %, more than half the cases were met as "undone" or "being processed" in all municipalities assessed in the period. The low completeness of reporting forms may compromise the quality of surveillance of TB cases. The results suggest the need for greater availability of HIV testing in these individuals.

  6. Characterization of welded HP 9-4-30 steel for the advanced solid rocket motor

    NASA Technical Reports Server (NTRS)

    Watt, George William

    1990-01-01

    Solid rocket motor case materials must be high-strength, high-toughness, weldable alloys. The Advanced Solid Rocket Motor (ASRM) cases currently being developed will be made from a 9Ni-4Co quench and temper steel called HP 9-4-30. These ultra high-strength steels must be carefully processed to give a very clean material and a fine grained microstructure, which insures excellent ductility and toughness. The HP 9-4-30 steels are vacuum arc remelted and carbon deoxidized to give the cleanliness required. The ASRM case material will be formed into rings and then welded together to form the case segments. Welding is the desired joining technique because it results in a lower weight than other joining techniques. The mechanical and corrosion properties of the weld region material were fully studied.

  7. [Association of Kaposi sarcoma--multiple myeloma. A new case].

    PubMed

    Cohen, J D; Thomas, E; Garnier, N; Hellier, I; Durand, L; Guilhou, J J; Baldet, P; Blotman, F

    2000-11-01

    Kaposi's disease is an angiogenic multifocal cancer process that has several forms, namely Mediterranean, African, HIV-associated, and secondary to a preexisting immunodepressive state (hematological disorder, corticosteroid therapy, immunodepressive treatment). Whatever its form, Kaposi's sarcoma is probably associated with a chronic viral human herpes type 8 infection (HHV8). This virus has been implicated in the pathogenesis of multiple myeloma (17 cases recorded to date). In the present study, a further case of Kaposi's sarcoma associated with multiple myeloma has been reported. However, Epstein-Barr virus, cytomegalovirus, hepatitis B and C, HIV and HHV8 serologies were negative. Radiotherapy on the lower limbs was initiated. It is concluded that HHV8 does not appear to play a pathogenic role in cases of multiple myeloma, given the rarity of the association between Kaposi's sarcoma/multiple myeloma/HHV8.

  8. Filament wound data base development, revision 1, appendix A

    NASA Technical Reports Server (NTRS)

    Sharp, R. Scott; Braddock, William F.

    1985-01-01

    Data are presented in tabular form for the High Performance Nozzle Increments, Filament Wound Case (FWC) Systems Tunnel Increments, Steel Case Systems Tunnel Increments, FWC Stiffener Rings Increments, Steel Case Stiffener Rings Increments, FWC External Tank (ET) Attach Ring Increments, Steel Case ET Attach Ring Increments, and Data Tape 8. The High Performance Nozzle are also presented in graphical form. The tabular data consist of six-component force and moment coefficients as they vary with angle of attack at a specific Mach number and roll angle. The six coefficients are normal force, pitching moment, side force, yawing moment, axial force, and rolling moment. The graphical data for the High Performance Nozzle Increments consist of a plot of a coefficient increment as a function of angle of attack at a specific Mach number and at a roll angle of 0 deg.

  9. Pathophysiology and management of intracranial arterial stenosis around the circle of Willis associated with hyperthyroidism: case reports and literature review.

    PubMed

    Matano, Fumihiro; Murai, Yasuo; Adachi, Koji; Kitamura, Takayuki; Teramoto, Akira

    2014-04-01

    Cases of moyamoya disease or intracranial arterial stenosis around the circle of Willis (M/IAS) associated with hyperthyroidism have been reported. However, most of these previous reports were of the ischemic form of M/IAS and primary hyperthyroidism. To the best of our knowledge, no studies have documented therapy for M/IAS associated with hyperthyroidism. We discuss four previously unreported cases, including those involving the intracerebral hemorrhage form and thyroid-stimulating hormone (TSH) secretion from a pituitary adenoma (secondary hyperthyroidism). We analyzed data from 52 previously reported cases, including the 4 cases presented here, and discuss M/IAS associated with hyperthyroidism, treatment options, pathophysiology, the ischemic and hemorrhagic forms, secondary hyperthyroidism, and the relevant literature. Hyperthyroidism results in thyrotoxicosis and the stimulation of the superior cervical ganglion by TSH antibodies and f-T3/f-T4. Consequently, hypercoagulability and stenosis of the cerebral artery can occur. There are many reports of ischemic M/IAS associated with hyperthyroidism. A conservative approach to treatment is important in such cases; for example, antithyroid therapy should be the first choice to treat ischemic M/IAS. There have been only a limited number of reports on hemorrhagic M/IAS. We presume that hemorrhagic M/IAS tears the weakened vasculature in a manner similar to that of normal M/IAS (with no complicating hyperthyroidism). The authors also reported M/IAS associated with secondary hyperthyroidism due to pituitary thyroid secreting hormone secreting adenoma.

  10. No more CKY two-forms in the NHEK

    NASA Astrophysics Data System (ADS)

    Mitsuka, Yoshihiro; Moutsopoulos, George

    2012-02-01

    We show that in the near-horizon limit of a Kerr-NUT-AdS black hole, the space of conformal Killing-Yano two-forms does not enhance and remains of dimension 2. The same holds for an analogous polar limit in the case of extremal NUT charge. We also derive the conformal Killing-Yano p-form equation for any background in an arbitrary dimension in the form of parallel transport.

  11. The ε-form of the differential equations for Feynman integrals in the elliptic case

    NASA Astrophysics Data System (ADS)

    Adams, Luise; Weinzierl, Stefan

    2018-06-01

    Feynman integrals are easily solved if their system of differential equations is in ε-form. In this letter we show by the explicit example of the kite integral family that an ε-form can even be achieved, if the Feynman integrals do not evaluate to multiple polylogarithms. The ε-form is obtained by a (non-algebraic) change of basis for the master integrals.

  12. Kinetics and mechanism of corrosion of SiC by molten salts

    NASA Technical Reports Server (NTRS)

    Jacobson, N. S.

    1986-01-01

    Corrosion of sintered alpha-SiC under thin films of Na2CO3/CO2, Na2SO4/O2, and Na2SO4/SO3 was investigated at 1000 C. Chemical analysis was used to follow silicate and silica evolution as a function of time. This information coupled with morphology observations leads to a detailed corrosion mechanism. In all cases the corrosion reactions occur primarily in the first few hours. In the Na2CO3/CO2 case, rapid oxidation and dissolution lead to a thick layer of silicate melt in about 0.25 h. After this, silica forms a protective layer on the carbide. In the Na2SO4/O2 case, a similar mechanism occurs. In the Na2SO4/SO3 case, a porous nonprotective layer of SiO2 grows directly on the carbide, and a silicate melt forms above this. In addition, SiO2 and regenerated Na2SO4 form at the melt/gas interface due to reaction of silicate with SO3 and SO2 + O2. The reaction slows when the lower silica layer becomes nonporous.

  13. Symmetry classes of the anisotropy tensors of quasielastic materials and a generalized Kelvin approach

    NASA Astrophysics Data System (ADS)

    Ostrosablin, N. I.

    2017-05-01

    The anisotropy matrices (tensors) of quasielastic (Cauchy-elastic) materials were obtained for all classes of crystallographic symmetries in explicit form. The fourth-rank anisotropy tensors of such materials do not have the main symmetry, in which case the anisotropy matrix is not symmetric. As a result of introducing various bases in the space of symmetric stress and strain tensors, the linear relationship between stresses and strains is represented in invariant form similar to the form in which generalized Hooke's law is written for the case of anisotropic hyperelastic materials and contains six positive Kelvin eigen moduli. It is shown that the introduction of modified rotation-induced deformation in the strain space can cause a transition to the symmetric anisotropy matrix observed in the case of hyperelasticity. For the case of transverse isotropy, there are examples of determination of the Kelvin eigen moduli and eigen bases and the rotation matrix in the strain space. It is shown that there is a possibility of existence of quasielastic media with a skew-symmetric anisotropy matrix with no symmetric part. Some techniques for the experimental testing of the quasielasticity model are proposed.

  14. Sporotrichosis in HIV-infected patients: report of 21 cases of endemic sporotrichosis in Rio de Janeiro, Brazil.

    PubMed

    Freitas, Dayvison Francis Saraiva; de Siqueira Hoagland, Brenda; do Valle, Antonio Carlos Francesconi; Fraga, Beatriz Barros; de Barros, Mônica Bastos; de Oliveira Schubach, Armando; de Almeida-Paes, Rodrigo; Cuzzi, Tullia; Rosalino, Cláudia Maria Valete; Zancopé-Oliveira, Rosely Maria; Gutierrez-Galhardo, Maria Clara

    2012-02-01

    Sporotrichosis is endemic in Rio de Janeiro, Brazil, and cases have been reported to be associated with HIV. This article describes the clinical manifestations and evolution of sporotrichosis in HIV-positive patients and constitutes the largest case series reported to date. There were 21 HIV-positive patients with sporotrichosis diagnosed by the recovery of the etiologic agent from 1999-2009. Sixteen patients (76.2%) were men and five (23.8%) were women, with a mean age of 41.2 years. Seven of these individuals were previously unaware of their HIV infection. Mean CD4 count was 346.4 cells/μl. The most frequent clinical presentations of sporotrichosis in these patients were the lymphocutaneous and disseminated form (seven patients each, 33.3%), followed by the widespread cutaneous form in five (23.8%), and fixed form in the remaining two (9.5%). In patients with the disseminated forms, clinical manifestations involved the skin in six, mucosa (nasal, oral, or conjunctival) in four, bone in two, and meninges in two. Eleven (52.4%) patients received itraconazole and eight (38.1%) amphotericin B contributing to an overall cure rate of 81%. Spontaneous cure was observed in one patient. The clinical forms of sporotrichosis varied according to the patients' immune status. The results demonstrate the importance of sporotrichosis as an opportunistic infection associated with AIDS in countries where the mycosis occurs.

  15. Lie algebra of conformal Killing-Yano forms

    NASA Astrophysics Data System (ADS)

    Ertem, Ümit

    2016-06-01

    We provide a generalization of the Lie algebra of conformal Killing vector fields to conformal Killing-Yano forms. A new Lie bracket for conformal Killing-Yano forms that corresponds to slightly modified Schouten-Nijenhuis bracket of differential forms is proposed. We show that conformal Killing-Yano forms satisfy a graded Lie algebra in constant curvature manifolds. It is also proven that normal conformal Killing-Yano forms in Einstein manifolds also satisfy a graded Lie algebra. The constructed graded Lie algebras reduce to the graded Lie algebra of Killing-Yano forms and the Lie algebras of conformal Killing and Killing vector fields in special cases.

  16. Scholarship improved by case report curriculum.

    PubMed

    Stephens, John; Wardrop, Richard

    2016-12-01

    The Accreditation Council for Graduate Medical Education (ACGME) requires that residents participate in scholarly activity. Case reports are an accessible form of resident scholarship, given the time required relative to other forms of research. Our paediatric residency lacked a curriculum for writing and presenting case reports. We created and implemented a brief curriculum for writing case reports and scientific posters. The curriculum consisted of two 1-hour didactic sessions, followed by mentoring during the writing process. The impact of the curriculum was measured via resident surveys about the material presented and by the rate of presentations of case reports made by residents at our departmental research day, before and after implementation. In the year of curriculum implementation, there were 15 case reports presented at the departmental research day, compared with an average of 4.7 per year in the three prior years. The resident (n = 85) participation rate increased from an average of 0.06 case reports per resident per year before implementation to 0.18 case reports per resident per year after implementation (p = 0.0023). Implementation of a case report curriculum with subsequent mentoring was associated with a marked increase in resident case report presentations at the departmental research day. These results suggest that even brief instruction and subsequent faculty mentorship in preparation of case reports can significantly improve resident participation in scholarly activity. © 2016 John Wiley & Sons Ltd.

  17. Various Forms of BRST Symmetry in Abelian 2-FORM Gauge Theory

    NASA Astrophysics Data System (ADS)

    Rai, Sumit Kumar; Mandal, Bhabani Prasad

    We derive the various forms of BRST symmetry using Batalin-Fradkin-Vilkovisky approach in the case of Abelian 2-form gauge theory. We show that the so-called dual BRST symmetry is not an independent symmetry but the generalization of BRST symmetry obtained from the canonical transformation in the bosonic and ghost sector. We further obtain the new forms of both BRST and dual-BRST symmetry by making a general transformation in the Lagrange multipliers of the bosonic and ghost sector of the theory.

  18. Kikuchi-Fujimoto Disease

    PubMed Central

    Dumas, Guillaume; Prendki, Virginie; Haroche, Julien; Amoura, Zahir; Cacoub, Patrice; Galicier, Lionel; Meyer, Olivier; Rapp, Christophe; Deligny, Christophe; Godeau, Bertrand; Aslangul, Elisabeth; Lambotte, Olivier; Papo, Thomas; Pouchot, Jacques; Hamidou, Mohamed; Bachmeyer, Claude; Hachulla, Eric; Carmoi, Thierry; Dhote, Robin; Gerin, Magdalena; Mekinian, Arsene; Stirnemann, Jérôme; Charlotte, Fréderic; Farge, Dominique; Molina, Thierry; Fain, Olivier

    2014-01-01

    Abstract Kikuchi-Fujimoto disease (KFD) is a rare cause of lymphadenopathy, most often cervical. It has been mainly described in Asia. There are few data available on this disease in Europe. We conducted this retrospective, observational, multicenter study to describe KFD in France and to determine the characteristics of severe forms of the disease and forms associated with systemic lupus erythematosus (SLE). We included 91 cases of KFD, diagnosed between January 1989 and January 2011 in 13 French hospital centers (median age, 30 ± 10.4 yr; 77% female). The ethnic origins of the patients were European (33%), Afro-Caribbean (32%), North African (15.4%), and Asian (13%). Eighteen patients had a history of systemic disease, including 11 with SLE. Lymph node involvement was cervical (90%), often in the context of polyadenopathy (52%), and it was associated with hepatomegaly and splenomegaly in 14.8% of cases. Deeper sites of involvement were noted in 18% of cases. Constitutional signs consisted mainly of fever (67%), asthenia (74.4%), and weight loss (51.2%). Other manifestations included skin rash (32.9%), arthromyalgia (34.1%), 2 cases of aseptic meningitis, and 3 cases of hemophagocytic lymphohistiocytosis. Biological signs included lymphocytopenia (63.8%) and increase of acute phase reactants (56.4%). Antinuclear antibodies (ANAs) and anti-DNA antibodies were present in 45.2% and 18% of the patients sampled, respectively. Concomitant viral infection was detected in 8 patients (8.8%). Systemic corticosteroids were prescribed in 32% of cases, hydroxychloroquine in 17.6%, and intravenous immunoglobulin in 3 patients. The disease course was always favorable. Recurrence was observed in 21% of cases. In the 33 patients with ANA at diagnosis, SLE was known in 11 patients, diagnosed concomitantly in 10 cases and in the year following diagnosis in 2 cases; 6 patients did not have SLE, and 4 patients were lost to follow-up (median follow-up, 19 mo; range, 3–39 mo). The presence of weight loss, arthralgia, skin lesions, and ANA was associated with the development of SLE (p < 0.05). Male sex and lymphopenia were associated with severe forms of KFD (p < 0.05). KFD can occur in all populations, irrespective of ethnic origin. Deep forms are common. An association with SLE should be investigated. A prospective study is required to determine the risk factors for the development of SLE. PMID:25500707

  19. Clinical Forms of Chikungunya in Gabon, 2010

    PubMed Central

    Caron, Mélanie; Grard, Gilda; Mombo, Illich; Bikié, Branly; Paupy, Christophe; Becquart, Pierre; Bisvigou, Ulrich; Leroy, Eric Maurice

    2012-01-01

    Background Chikungunya virus (CHIKV) has caused multiple outbreaks in tropical and temperate areas worldwide, but the clinical and biological features of this disease are poorly described, particularly in Africa. We report a prospective study of clinical and biological features during an outbreak that occurred in Franceville, Gabon in 2010. Methodology/Principal Findings We collected, in suspect cases (individuals presenting with at least one of the following symptoms or signs: fever, arthralgias, myalgias, headaches, rash, fatigue, nausea, vomiting, diarrhea, bleeding, or jaundice), blood samples, demographic and clinical characteristics and outcome. Hematological and biochemical tests, blood smears for malaria parasites and quantitative PCR for CHIKV then dengue virus were performed. CHIKV+ patients with concomitant malaria and/or dengue were excluded from the study. From May to July 2010, data on 270 laboratory-confirmed CHIK patients were recorded. Fever and arthralgias were reported by respectively 85% and 90% of patients, while myalgias, rash and hemorrhage were noted in 73%, 42% and 2% of patients. The patients were grouped into 4 clinical categories depending on the existence of fever and/or joint pain. On this basis, mixed forms accounted for 78.5% of cases, arthralgic forms 12.6%, febrile forms 6.7% and unusual forms (without fever and arthralgias) 2.2%. No cases of organ failure or death were reported. Elevated liver enzyme and creatinine levels, anemia and lymphocytopenia were the predominant biological abnormalities, and lymphocytopenia was more severe in patients with high viral loads (p = 0.01). Conclusions/Significance During CHIK epidemics, some patients may not have classical symptoms. The existence of unusual forms and the absence of severe forms of CHIK call for surveillance to detect any change in pathogenicity. PMID:22348166

  20. Organogels resulting from competing self-assembly units in the gelator: Structure, dynamics, and photophysical behavior of gels formed from cholesterol-stilbene and cholesterol-squaraine gelators

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Geiger, C.; Stanescu, M.; Chen, L.

    1999-03-30

    Organogels formed from novel organic gelators containing a cholesterol tethered to squaraine dyes or trans-stilbene derivatives have been studied from several different perspectives. The two types of molecules are active toward several organic liquids, gelling in some cases at w/w percentages as low as 0.1. While relatively robust, macroscopically dry gels are formed in several cases, studies with a variety of probes indicate that much of the solvent may exist in domains that are essentially liquid-like in terms of their microenvironment. The gels have been imaged by atomic force microscopy and conventional and fluorescence microscopy, monitoring both the gelator fluorescencemore » in the case of the stilbene-cholesterol gels and, the fluorescence of solutes dissolved in the solvent. Remarkably, findings show that several of the gels are composed of similarly appearing fibrous structures visible at the nano-, micro-, and macroscale.« less

  1. Somatic GNAQ mutation in the forme fruste of Sturge-Weber syndrome

    PubMed Central

    Harvey, A. Simon; Malone, Stephen; Damiano, John A.; Do, Hongdo; Ye, Zimeng; McQuillan, Lara; Maixner, Wirginia; Kalnins, Renate; Nolan, Bernadette; Wood, Martin; Ozturk, Ezgi; Jones, Nigel C.; Gillies, Greta; Pope, Kate; Lockhart, Paul J.; Dobrovic, Alexander; Leventer, Richard J.; Scheffer, Ingrid E.

    2018-01-01

    Objective To determine whether the GNAQ R183Q mutation is present in the forme fruste cases of Sturge-Weber syndrome (SWS) to establish a definitive molecular diagnosis. Methods We used sensitive droplet digital PCR (ddPCR) to detect and quantify the GNAQ mutation in tissues from epilepsy surgery in 4 patients with leptomeningeal angiomatosis; none had ocular or cutaneous manifestations. Results Low levels of the GNAQ mutation were detected in the brain tissue of all 4 cases—ranging from 0.42% to 7.1% frequency—but not in blood-derived DNA. Molecular evaluation confirmed the diagnosis in 1 case in which the radiologic and pathologic data were equivocal. Conclusions We detected the mutation at low levels, consistent with mosaicism in the brain or skin (1.0%–18.1%) of classic cases. Our data confirm that the forme fruste is part of the spectrum of SWS, with the same molecular mechanism as the classic disease and that ddPCR is helpful where conventional diagnosis is uncertain. PMID:29725622

  2. [A prognostic assessment of louse-borne typhus (Rickettsia prowazekii infection) in Russia].

    PubMed

    Onishchenko, G G; Lukin, E P; Syskova, T G

    1997-01-01

    From the 1950s to 1974 R.prowazekii infection was registered on the territory of Russia, mainly in the form of Brill's disease, represented by some individual cases in the focus of infection. In 0.25% of all of cases rickettsiosis was linked with group outbreaks of the family character (14 events), reflecting the epidemic form of the disease. From 1974 until the present time the correlation between the sources of infection and the infestation of the population with lice dropped below the critical level, ensuring the transmission of the infective agent among the susceptible human population. This led to the steady disappearance of rickettsiosis (a decrease in the number of rickettsiosis cases from several thousand in the 60s to less than 100 in 1991) due to natural demographic processes. After the disintegration of the USSR, the migration of the population from some regions, especially from those where military conflicts took place, did not affect this process. The return of the epidemic form of rickettsiosis in Russia is impossible.

  3. Advanced Containment System

    DOEpatents

    Kostelnik, Kevin M.; Kawamura, Hideki; Richardson, John G.; Noda, Masaru

    2005-02-08

    An advanced containment system for containing buried waste and associated leachate. The advanced containment system comprises a plurality of casing sections with each casing section interlocked to an adjacent casing section. Each casing section includes a complementary interlocking structure that interlocks with the complementary interlocking structure on an adjacent casing section. A barrier filler substantially fills the casing sections and may substantially fill the spaces of the complementary interlocking structure to form a substantially impermeable barrier. Some of the casing sections may include sensors so that the casing sections and the zone of interest may be remotely monitored after the casing sections are emplaced in the ground.

  4. A 10-session cognitive-behavioral therapy (CBT-T) for eating disorders: Outcomes from a case series of nonunderweight adult patients.

    PubMed

    Waller, Glenn; Tatham, Madeleine; Turner, Hannah; Mountford, Victoria A; Bennetts, Alison; Bramwell, Kate; Dodd, Julie; Ingram, Lauren

    2018-03-01

    Existing forms of evidence-based cognitive behavior therapy for eating disorders (CBT-ED) are relatively effective for nonunderweight cases. However, they are also expensive compared to CBT for other disorders. This study reports the first outcomes for a shorter, 10-session form of CBT-ED (CBT-T) for such cases, designed to be less demanding of resources. A case series of 106 nonunderweight eating disordered cases were considered for this effectiveness study. A protocolized 10-session version of CBT-ED was delivered by clinical assistants, under supervision. Measures assessed eating attitudes and behaviors, anxiety, depression, personality pathology, and the working alliance. Intention-to-treat analyses were used. Suitability, acceptability, working alliance ratings, and retention were all positive. Outcomes by the end of therapy and at three-month follow-up were positive for all symptoms, with levels of change, abstinence and remission that were comparable to those from effectiveness studies of longer forms of CBT. Higher levels of pretreatment anxiety predicted retention in treatment, but no factors predicted poorer response. Early change in eating attitudes and the working alliance were the strongest predictors of a positive response. This 10-session form of CBT-ED for nonunderweight eating disorders performed at a level that is comparable to versions of CBT-ED that are twice as long, despite being delivered by nonspecialist therapists. Replication and longer-term follow-ups are needed to ensure retained effects. However, CBT-T has promise as a therapy for use in a range of healthcare settings, to enhance access to treatment for such eating disorders. © 2018 Wiley Periodicals, Inc.

  5. Color picture drawings without form and eye movements: a case report of visual form agnosia in a girl.

    PubMed

    Kaga, Kimitaka; Shindo, Mitsuko

    2012-04-01

    The case of an 8-year-old girl who manifested cortical blindness and whose color drawings of faces and objects were without outlines is reported. Her birth was uneventful. When she was 10 months old, she fell down to the floor from a chair, resulting in a subarachnoidal hemorrhage. A repeat brain MRI revealed localized lesions in the visual cortices in the right and left hemispheres. As she grew older she was found to have visual imperceptions. She was found to have difficulties in learning visually the names of objects with form and letters, and in recognizing faces of her family. However, she was able to discriminate well the colors of faces and objects and learn easily the names of the objects with form by touching. She seemed to utilize subcortical vision for seeing colors of faces and objects.

  6. Disaster media coverage and psychological outcomes: descriptive findings in the extant research.

    PubMed

    Pfefferbaum, Betty; Newman, Elana; Nelson, Summer D; Nitiéma, Pascal; Pfefferbaum, Rose L; Rahman, Ambreen

    2014-09-01

    This review of the literature on disaster media coverage describes the events, samples, and forms of media coverage (television, newspapers, radio, internet) studied and examines the association between media consumption and psychological outcomes. A total of 36 studies representing both man-made and natural events met criteria for review in this analysis. Most studies examined disaster television viewing in the context of terrorism and explored a range of outcomes including posttraumatic stress disorder (PTSD) caseness and posttraumatic stress (PTS), depression, anxiety, stress reactions, and substance use. There is good evidence establishing a relationship between disaster television viewing and various psychological outcomes, especially PTSD caseness and PTS, but studies are too few to draw definitive conclusions about the other forms of media coverage that have been examined. As media technology continues to advance, future research is needed to investigate these additional media forms especially newer forms such as social media.

  7. Terra firma-forme dermatosis: a retrospective review of 31 patients.

    PubMed

    Berk, David R

    2012-01-01

    Terra firma-forme dermatosis is an idiopathic condition characterized by acquired, dirtlike plaques despite normal hygiene. A diagnosis can be reached by removing lesions with gentle alcohol swabbing. Although Terra firma-forme dermatosis was first described more than 20 years ago and is thought to be not uncommon in clinical practice, it has never been systematically studied. There are few publications about this condition, including no case series of more than six patients. In particular, little is known about the incidence, peak age groups, and most common locations of Terra firma-forme dermatosis. A retrospective review was conducted to identify cases of Terra firma-forme dermatosis in a single-provider practice consisting of 55% pediatric and 45% adult patients. Thirty-one patients with Terra firma-forme dermatosis were identified, including 10 who presented with Terra firma-forme dermatosis as their primary concern. Only two patients were older than 17 years. The median duration of lesions was 4 months. The most common lesion locations were the neck, ankles, and face. Before presenting to the dermatology clinic, three patients had undergone endocrine evaluations, and four had been prescribed topical corticosteroids. Terra firma-forme dermatosis is relatively common and most often occurs in children on the neck or posterior malleolus. This series exemplifies the importance of recognizing Terra firma-forme dermatosis so as to provide rapid relief for patients and avoid unnecessary tests and treatments. © 2011 Wiley Periodicals, Inc.

  8. Al-Qaeda-Syria (AQS): An Al-Qaeda Affiliate Case Study

    DTIC Science & Technology

    2017-10-01

    comparative methodology that included eight case studies on groups affiliated or associated with Al-Qaeda. These case studies were then used as a...Case Study Zack Gold With contributions from Pamela G. Faber October 2017 This work was performed under Federal Government...for Stability and Development Center for Strategic Studies REPORT DOCUMENTATION PAGE Form Approved OMB No. 0704-0188 Public reporting burden

  9. 76 FR 64377 - Agency Information Collection Activities: Proposed Collection; Comments Requested: Alien's Change...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-18

    ... Collection; Comments Requested: Alien's Change of Address Forms: 33/BIA Board of Immigration Appeals and 33... approved collection. (2) Title of the Form/Collection: Alien's Change of Address Forms: 33/BIA Board of... determine where to send notices of the next administrative action or of any decisions in an alien's case. (5...

  10. 76 FR 80403 - Agency Information Collection Activities; Proposed collection; Comments Request: Alien's Change...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-23

    ... collection; Comments Request: Alien's Change of Address Form: 33/BIA Board of Immigration Appeal; 33/IC... Collection. (2) Title of the Form/Collection: Alien's Change of Address Forms 33/BIA Board of Immigration... send notices of the next administrative action or of any decisions in an alien's case. (5) An estimate...

  11. 26 CFR 601.503 - Requirements of power of attorney, signatures, fiduciaries and Commissioner's authority to...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... taxpayer. In the case of an insolvent taxpayer, form 56, “Notice Concerning Fiduciary Relationship,” should... and effect at the time the form 56, “Notice Concerning Fiduciary Relationship,” is filed. (ii... form 56, “Notice Concerning Fiduciary Relationship,” should be filed by the residuary legatee(s...

  12. 26 CFR 601.503 - Requirements of power of attorney, signatures, fiduciaries and Commissioner's authority to...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... taxpayer. In the case of an insolvent taxpayer, form 56, “Notice Concerning Fiduciary Relationship,” should... and effect at the time the form 56, “Notice Concerning Fiduciary Relationship,” is filed. (ii... form 56, “Notice Concerning Fiduciary Relationship,” should be filed by the residuary legatee(s...

  13. 26 CFR 601.503 - Requirements of power of attorney, signatures, fiduciaries and Commissioner's authority to...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... taxpayer. In the case of an insolvent taxpayer, form 56, “Notice Concerning Fiduciary Relationship,” should... and effect at the time the form 56, “Notice Concerning Fiduciary Relationship,” is filed. (ii... form 56, “Notice Concerning Fiduciary Relationship,” should be filed by the residuary legatee(s...

  14. Selective Attention in Web Forms: An Exploratory Case Study with Older People

    ERIC Educational Resources Information Center

    Sayago, Sergio; Guijarro, Jose-Maria; Blat, Josep

    2012-01-01

    This article reports on an exploratory study aimed to identify which ways of marking required and optional fields help older people fill in web forms correctly. Drawing on a pilot study and selective attention research in ageing, modified versions of widely used forms were created, in which standard asterisks were replaced with one of three…

  15. A Case Study: A Teacher's Instruction of Writing in Rural Northeast Mississippi

    ERIC Educational Resources Information Center

    Anderson-Crane, Betty

    2008-01-01

    When writing instructors use form (essay form) based upon state testing standards on the state rubric to guide students in writing, they may be teaching form to limit higher level thinking content (Albertson, 2004). Instructors may not feel confident enough in their teaching of writing for high-stakes' testing; therefore, they may instruct…

  16. 31 CFR 1024.320 - Reports by mutual funds of suspicious transactions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... the Financial Crimes Enforcement Network in accordance with the instructions to the Form SAR-SF. (3... delay filing a Form SAR-SF for an additional 30 calendar days to identify a suspect, but in no case...-866-556-3974 in addition to filing timely a Form SAR-SF if required by this section. The mutual fund...

  17. 31 CFR 1024.320 - Reports by mutual funds of suspicious transactions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... the Financial Crimes Enforcement Network in accordance with the instructions to the Form SAR-SF. (3... delay filing a Form SAR-SF for an additional 30 calendar days to identify a suspect, but in no case...-866-556-3974 in addition to filing timely a Form SAR-SF if required by this section. The mutual fund...

  18. 31 CFR 1024.320 - Reports by mutual funds of suspicious transactions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... the Financial Crimes Enforcement Network in accordance with the instructions to the Form SAR-SF. (3... delay filing a Form SAR-SF for an additional 30 calendar days to identify a suspect, but in no case...-866-556-3974 in addition to filing timely a Form SAR-SF if required by this section. The mutual fund...

  19. 7 CFR 1.325 - Form, filing and service of papers.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Form, filing and service of papers. 1.325 Section 1... and service of papers. (a) Form. (1) The original and two copies of all papers in a proceeding conducted under this subpart shall be filed with the ALJ assigned to the case. (2) Every pleading and paper...

  20. 75 FR 54149 - Agency Information Collection Activities: Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-03

    ... current basic case-mix adjusted composite payment system and the methodologies for the reimbursement of... during the transition will be paid under the basic case-mix adjusted composite payment system. Form...

  1. [Digital angiography and lipiodol computerized tomography in the anatomopathological framework of hepatocarcinoma].

    PubMed

    Pozzi-Mucelli, R; Pozzi-Mucelli, R; Pagnan, L; Dalla Palma, L

    1994-12-01

    The introduction of therapies other than conventional surgery of hepatocellular carcinoma (HCC) requires an accurate pathologic classification, which is important because it is well known that HCC may have multicentric growth. The Liver Cancer Study Group of Japan has proposed a classification dividing HCCs into three macroscopic forms from the pathologic point of view: nodular, massive and infiltrating HCCs. The nodular type is subdivided into four types: single nodular type, single nodular type with surrounding proliferation, multinodular fused type and multinodular type. Forty-six HCC patients were examined with Lipiodol Computed Tomography (LCT) to investigate the agreement between pathologic and imaging findings. LCT proved to be in close agreement with pathologic findings. Sixteen cases were classified as type I (single nodular type), 8 as type II (single nodular type with limited foci), 1 as type III (multinodular fused type), 18 as type IV (multiple nodular type with diffuse foci) and 3 cases as type V (massive form). No cases of infiltrative forms were observed in our series. Based on LCT findings, the capabilities of digital subtraction angiography (DSA) were studied in the pathologic classification of HCCs. DSA exhibited some limitations in the pathologic classification of HCCs in 5 of 16 patients with type I lesions. In these cases DSA suggested false-positive diagnoses because of regenerative nodules in cirrhotic liver in 3 cases and of daughter nodules (not confirmed at LCT) in 2 cases. In 7 of 8 patients with type II HCCs, DSA failed to show the daughter nodules surrounding the main nodule. In the 18 patients with multiple distant nodules (type IV), DSA was less sensitive in defining nodule number and site. In the massive form, the information obtained with LCT and DSA was comparable. In conclusion, LCT should be considered a basic examination in the study of HCC extent. Based on LCT findings, the most appropriate treatment can be selected, be it surgery, alcohol injection, or intraarterial chemoembolization.

  2. Discrimination of bed form scales using robust spline filters and wavelet transforms: Methods and application to synthetic signals and bed forms of the Río Paraná, Argentina

    NASA Astrophysics Data System (ADS)

    Gutierrez, Ronald R.; Abad, Jorge D.; Parsons, Daniel R.; Best, James L.

    2013-09-01

    There is no standard nomenclature and procedure to systematically identify the scale and magnitude of bed forms such as bars, dunes, and ripples that are commonly present in many sedimentary environments. This paper proposes a standardization of the nomenclature and symbolic representation of bed forms and details the combined application of robust spline filters and continuous wavelet transforms to discriminate these morphodynamic features, allowing the quantitative recognition of bed form hierarchies. Herein the proposed methodology for bed form discrimination is first applied to synthetic bed form profiles, which are sampled at a Nyquist ratio interval of 2.5-50 and a signal-to-noise ratio interval of 1-20 and subsequently applied to a detailed 3-D bed topography from the Río Paraná, Argentina, which exhibits large-scale dunes with superimposed, smaller bed forms. After discriminating the synthetic bed form signals into three-bed form hierarchies that represent bars, dunes, and ripples, the accuracy of the methodology is quantified by estimating the reproducibility, the cross correlation, and the standard deviation ratio of the actual and retrieved signals. For the case of the field measurements, the proposed method is used to discriminate small and large dunes and subsequently obtain and statistically analyze the common morphological descriptors such as wavelength, slope, and amplitude of both stoss and lee sides of these different size bed forms. Analysis of the synthetic signals demonstrates that the Morlet wavelet function is the most efficient in retrieving smaller periodicities such as ripples and smaller dunes and that the proposed methodology effectively discriminates waves of different periods for Nyquist ratios higher than 25 and signal-to-noise ratios higher than 5. The analysis of bed forms in the Río Paraná reveals that, in most cases, a Gamma probability distribution, with a positive skewness, best describes the dimensionless wavelength and amplitude for both the lee and stoss sides of large dunes. For the case of smaller superimposed dunes, the dimensionless wavelength shows a discrete behavior that is governed by the sampling frequency of the data, and the dimensionless amplitude better fits the Gamma probability distribution, again with a positive skewness. This paper thus provides a robust methodology for systematically identifying the scales and magnitudes of bed forms in a range of environments.

  3. 21 CFR 312.62 - Investigator recordkeeping and record retention.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... provide for disposition of the unused supplies of the drug under § 312.59. (b) Case histories. An... drug or employed as a control in the investigation. Case histories include the case report forms and... 21 Food and Drugs 5 2014-04-01 2014-04-01 false Investigator recordkeeping and record retention...

  4. 21 CFR 312.62 - Investigator recordkeeping and record retention.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... provide for disposition of the unused supplies of the drug under § 312.59. (b) Case histories. An... drug or employed as a control in the investigation. Case histories include the case report forms and... 21 Food and Drugs 5 2012-04-01 2012-04-01 false Investigator recordkeeping and record retention...

  5. 21 CFR 312.62 - Investigator recordkeeping and record retention.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... provide for disposition of the unused supplies of the drug under § 312.59. (b) Case histories. An... drug or employed as a control in the investigation. Case histories include the case report forms and... 21 Food and Drugs 5 2011-04-01 2011-04-01 false Investigator recordkeeping and record retention...

  6. 21 CFR 312.62 - Investigator recordkeeping and record retention.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... provide for disposition of the unused supplies of the drug under § 312.59. (b) Case histories. An... drug or employed as a control in the investigation. Case histories include the case report forms and... 21 Food and Drugs 5 2013-04-01 2013-04-01 false Investigator recordkeeping and record retention...

  7. Fall about laughing: a case of laughter syncope.

    PubMed

    Bragg, Matthew J

    2006-01-01

    Laughter syncope is an unusual but recognized form of situational syncope likely to have a similar pathophysiological origin to tussive syncope. There are few case reports of this syndrome in the literature. Patients, as in this case, might present initially to the ED, and laughter should be considered among the numerous differentials for syncope.

  8. Case Study: Camptocormia, a Rare Conversion Disorder.

    ERIC Educational Resources Information Center

    Rajmohan, Velayudhan; Thomas, Biju; Sreekumar, Kumaran

    2004-01-01

    Camptocormia is a condition characterized by severe frontal flexion of the spinal cord and knees, with passive drooping of both arms. It occurs as a form of conversion disorder. Some cases are associated with behavioral problems. A case of camptocormia of 2-year duration in a south Indian adolescent girl with oppositional defiant disorder and…

  9. Cases on Global E-Learning Practices: Successes and Pitfalls

    ERIC Educational Resources Information Center

    Sharma, Ramesh C., Ed.; Mishra, Sanjaya, Ed.

    2007-01-01

    "Cases on Global E-Learning Practices: Successes and Pitfalls" looks into global practices of e-learning, examining the successes and failures of e-learning professionals. It provides a judicious mix of practical experiences and research in the form of case studies. Written by experts from all over the globe, this book shows how to…

  10. Teaching Case: Enterprise Architecture Specification Case Study

    ERIC Educational Resources Information Center

    Steenkamp, Annette Lerine; Alawdah, Amal; Almasri, Osama; Gai, Keke; Khattab, Nidal; Swaby, Carval; Abaas, Ramy

    2013-01-01

    A graduate course in enterprise architecture had a team project component in which a real-world business case, provided by an industry sponsor, formed the basis of the project charter and the architecture statement of work. The paper aims to share the team project experience on developing the architecture specifications based on the business case…

  11. [Pain management in home hospice care].

    PubMed

    Sakai, T; Sato, A

    1998-12-01

    Among 35 cases with terminal home care cancer patients, 23 (65.7%) cases developed pain. Twenty of these cases (87%) were treated with morphine. MS-contin and Anpec (suppositorium) were given to the patients. The two forms were jointly administered in 20% of them. NSAIDS and other adjuvant analgesics were given to 85% of them. Average dose of morphine were 173.5 +/- 357.5 mg. Adverse morphine side effects were treated with medication. In any case morphine administration was not discontinued due to its adverse effects. Some 82% of the patients died at home. No case dropped out of home care due to unsuccessful pain management. Successful pain management is necessary to implement home terminal care, and both patient and family should fully understand the status and prognosis of the incurable disease. Moreover, medical professionals (home care doctors, home care nurses and hospital doctors) should collaborate to form the temporal, adequate and seamless networking in caring and supporting terminal patients and their families.

  12. Computed tomography of lobar collapse: 2. Collapse in the absence of endobronchial obstruction

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Naidich, D.P.; McCauley, D.I.; Khouri, N.F.

    1983-10-01

    The computed tomographic appearance of collapse without endobronchial obstruction is reviewed. These 57 cases were classified by the etiology of collapse. The largest group consisted of 29 patients with passive atelectasis, i.e., collapse secondary to fluid, air, or both in the pleural space. Twenty-three of 29 proved secondary to malignant pleural disease. Computed tomography accurately predicted a malignant etiology in 22 of 23 cases. The second largest group of patients had lobar collapse secondary to cicatrization from chronic inflammation. In all cases the underlying etiology was tuberculosis. Radiation caused adhesive atelectasis in six patients secondary to a lack of productionmore » of surfactant. In each case a sharp line of demarcation could be defined between normal and abnormal collapsed pulmonary parenchyma. Three cases of unchecked tumor growth caused a peripheral form of collapse (replacement atelectasis). This form of collapse was characterized by an absence of endobronchial obstruction and extensive tumor not delineated by the normal boundaries of the pulmonary lobes.« less

  13. Granulomatous Lobular Mastitis Following Drug-Induced Galactorrhea and Blunt Trauma.

    PubMed

    Cserni, Gábor; Szajki, Károly

    1999-11-01

    We report a single case of chronic granulomatous lobular mastitis following metoclopramide-related galactorrhea and a blunt trauma in a young parous woman who underwent two conservative operations before becoming symptom-free. We have found only two other literature cases associated with hyperprolactinemia, and our case could be another of this etiologic group. The absence of well-formed granulomas in the first histology specimen in the present case was misleading; it was reinterpreted as granulomatous mastitis only after the second specimen was examined. Reinterpretation was based on the lobular distribution of a lymphoplasmocytic infiltrate (nonspecific chronic lobulitis) and the presence of epithelioid cell sheets and neutrophils in the absence of well-formed granulomas. The case lends further support to the theory of a local immune response initiated by the secreted material or by one of its components in the formation of granulomas. However, contributory factors such as the trauma in this case (a blow from a shovel handle) or systemic disease in others may play a role in the development of the disease, which in some instances may represent a pattern of tissue reactions to different noxious agents.

  14. [Poliomyelitis case surveillance data management in Burkina Faso].

    PubMed

    Drabo, Koiné Maxime; Nana, Félicité; Kouassi, Kouassi Lazare; Konfé, Salifou; Hien, Hervé; Saizonou, Jacques; Ouedraogo, Tinoaga Laurent

    2015-01-01

    The global initiative for poliomyelitis eradication can only remain relevant if survey systems are regularly assessed. In order to identify shortcomings and to propose improvement, the data collection and transmission during case investigation were assessed in the Banfora health district in Burkina Faso. The survey targeted six (6) primary health centres, the district laboratory and the national laboratory, all involved in the poliomyelitis surveillance system. Data from registers, forms documenting suspected cases, stool sample forms and weekly reports were collected by means of a data grid. Data from actors involved in the poliomyelitis case investigation system were collected by means of an individual questionnaire. The reactivity of investigating suspected cases was satisfactory with a median alert questionnaire notification time of 18 hours. The completeness of the reporting system was satisfactory. Nevertheless, the promptness of data management by primary heath centres and the national laboratory remained unsatisfactory. Evaluation of data management revealed logistic and organization shortcomings. The overall efficacy of the poliomyelitis surveillance could be improved by using management tools for laboratory supplies, collecting data related to the homes of suspected cases and implementing a cold chain maintenance plan.

  15. Interface Instabilities in the Interstellar Medium

    NASA Technical Reports Server (NTRS)

    Hunter, J. H., Jr.; Siopis, C.; Whitaker, R. W.; Lovelace, R. V. E.

    1995-01-01

    In the present communication, we reexamine two limiting cases of star-forming mechanisms involving self-gravity, thermodynamics, and velocity fields, that we believe must be ubiquitous in the ISM -- the generally oblique collision of supersonic gas streams or turbulent eddies. The general case of oblique collisions has not yet been examined. However, two limiting cases have been studied in detail: (1) The head-on collision of two identical gas streams that form dense, cool accretion shocks that become unstable and may form Jeans mass clouds, which subsequently undergo collapse. (2) Linearly unstable tangential velocity discontinuities, which result in Kelvin-Helmholtz (K-H) instabilities and related phenomena. The compressible K-H instabilities exhibit rich and unexpected behaviors. Moreover a new thermal-dynamic (T-D) mode was discovered that arises from the coupling of the perturbed thermal behavior and the unperturbed flow. The T-D mode has the curious characteristic that it may be strongly unstable to interface modes when the global modes in either medium are absolutely thermally stable. In the present communication additional models of case 1 are described and discussed, and self-gravity is added in the linear theory of tangential discontinuities, case 2. We prove that self-gravity fundamentally changes the behavior of interfacial modes -- density discontinuities (or steps) are inherently unstable on roughly the free-fall timescale of the denser medium to perturbations of all wavelengths.

  16. Urinary excretion of glycosaminoglycans in the various forms of gargoylism

    PubMed Central

    Manley, G.; Williams, U.

    1969-01-01

    The urinary excretion of glycosaminoglycans in 28 cases of gargoylism, embracing the Hurler, Hunter, Sanfilippo, Morquio, and Scheie syndromes (McKusick, 1966), has been examined using the cetylpyridinium chloride (CPC) turbidity test, the uronic acid/creatinine ratio, and the electrophoretic pattern of urine concentrates, as routine procedures. Ion-exchange column chromatographic techniques were also employed for the fractionation of glycosaminoglycans and aminosugars. Molecular weights were investigated by gel filtration and ultracentrifugation. The CPC turbidity test was positive in every case. The uronic acid/creatinine ratio provided a sensitive index of increased glycosaminoglycan excretion. Cases of the Hurler syndrome showed the highest, and cases of the Morquio and Scheie syndromes the lowest, ratios. A correlation was observed between the uronic acid/creatinine ratio and the clinical severity of the disease. Cellulose acetate electrophoresis differentiated clearly between the two major forms of gargoylism, the Hurler and Sanfilippo syndromes, but differentiation between the Hurler, Hunter, and Scheie syndromes was more difficult on electrophoretic data alone. Results obtained with cases diagnosed as the Morquio syndrome were disappointing. The existence of formes frustes of the Sanfilippo syndrome among the mentally subnormal is predicted. Errors caused by bacterial contamination of urine samples are emphasized. The atypical behaviour of urinary glycosaminoglycans in analytical procedures is discussed. Molecular weight studies suggested heterogeneity. The nature of the basic defect in gargoylism is discussed. Images PMID:4239429

  17. [Guillain-Barré syndrome with preserved reflexes].

    PubMed

    Zouiri, G; Abilkassem, R; Zerhouni, A; Dini, N; Agadr, A

    2016-05-01

    Guillain-Barré is a rare, autoimmune disease of the peripheral nervous system. It can affect all ages beginning in the intrauterine or neonatal period. Clinical forms are diverse and include acute motor axonal neuropathy (AMAN). We report on a pediatric case of AMAN. A 2.5-year-old child presented with acute flaccid paralysis and preserved reflexes. Etiologic investigations argued in favor of Guillain-Barré syndrome in its AMAN form. Treatment based on IV immunoglobulins resulted in a total decline of paralysis and motor recovery. The AMAN form of Guillain-Barré syndrome should be considered as a potential diagnosis in all cases of acute flaccid paralysis with preserved reflexes. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

  18. A web-based endodontic case difficulty assessment tool.

    PubMed

    Shah, P K; Chong, B S

    2018-07-01

    To develop a web-based tool to facilitate identification, evaluation and management of teeth requiring endodontic treatment. Following a literature search and thorough analysis of existing case difficulty assessment forms, the web-based tool was developed using an online survey builder (Qualtrics, Qualtrics Lab, UT, USA). Following feedback from a pilot study, it was refined and improved. A study was performed, using the updated version (EndoApp) on a cohort (n = 53) of dental professionals and dental students. The participants were e-mailed instructions detailing the assessment of five test cases using EndoApp, followed by completion of a structured feedback form. Analysis of the EndoApp responses was used to evaluate usage times, whereas the results of the feedback forms were used to assess user experience and relevance, other potential applications and comments on further improvement/s. The average usage time was 2 min 7 s; the average times needed for the last three (Cases 3-5) were significantly less than the preceding two (Cases 1 & 2) test cases. An overwhelming majority of participants expressed favourable views on user experience and relevance of the web-based case difficulty assessment tool. Only two participants (4%) were unlikely or very unlikely to use EndoApp again. The potential application of EndoApp as an 'educational tool' and for 'primary care triage' was deemed the most popular features and of greater importance than the secondary options of 'fee setting' and as a 'dento-legal justification tool'. Within the study limitations, owing to its ability to quantify the level of difficulty and provide guidance, EndoApp was considered user-friendly and helped facilitate endodontic case difficulty assessment. From the feedback, further improvements and the development of a Smartphone App version are in progress. EndoApp may facilitate treatment planning, improve treatment cost-effectiveness and reduce frequency of procedural errors by providing appropriate guidance on endodontic case management.

  19. [Tuberculous pyopneumothorax: about 18 cases].

    PubMed

    Hicham, Souhi; Hanane, El Ouazzani; Hicham, Janah; Ismaïl, Rhorfi; Ahmed, Abid

    2016-01-01

    Tuberculous pyopneumothorax is a rare but serious complication of evolutive pulmonary tuberculosis. We report a series of 18 cases with tuberculous pyopneumothorax admitted to the Pneumo-Phthisiology Department of the Mohammed V Military Teaching Hospital in Rabat between January 2005 and December 2009. Our study included 15 men and 3 women, the average age was 35 ± 7 years. 4 patients were diabetic. Smoking was found in 9 cases. Right-sided pneumothorax was found in 13 cases. Chest radiograph showed cavitary lesions in 15 patients and extensive bilateral lesions in 8 cases. The search for Mycobacterium tuberculosis in the fluid from the gastric tube was positive in 16 cases. Chest drainage associated with antituberculosis treatment according to the 2SRHZ/7RH regimen and respiratory kinesitherapy were performed in all cases. The average duration of pleural drainage was 4 weeks. In 3 cases we noted persistent pleural suppuration requiring pleural toilet using thoracoscopy with pleurectomy and limited pulmonary resection to eliminate tuberculous parenchymal lesions and the persistence of a large pleural pocket with restrictive ventilatory defect that required surgery for pleural decortication in two cases. The outcome was favorable with minimal pachypleuritis as sequelae in the remaining cases. Tuberculous pyopneumothorax is a severe form, which is often associated with active cavitary tuberculosis. Evolution is generally progressive despite antituberculosis treatment and thoracic drainage, hence the need for early diagnosis and treatment of all forms of tuberculosis.

  20. 31 CFR 341.10 - Reissue.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... the case of a bond registered in beneficiary form upon the owner's request on Form PD 3564. No consent..., Parkersburg, WV 26101. [28 FR 405, Jan 16, 1963, as amended at 42 FR 21611, Apr. 28, 1977; 42 FR 57123, Nov. 1...

  1. 31 CFR 341.10 - Reissue.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... the case of a bond registered in beneficiary form upon the owner's request on Form PD 3564. No consent..., Parkersburg, WV 26101. [28 FR 405, Jan 16, 1963, as amended at 42 FR 21611, Apr. 28, 1977; 42 FR 57123, Nov. 1...

  2. 31 CFR 341.10 - Reissue.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... the case of a bond registered in beneficiary form upon the owner's request on Form PD 3564. No consent..., Parkersburg, WV 26101. [28 FR 405, Jan 16, 1963, as amended at 42 FR 21611, Apr. 28, 1977; 42 FR 57123, Nov. 1...

  3. A young woman who killed 5 of her own babies: A case of multiple neonaticide.

    PubMed

    Huchzermeier, Christian; Heinzen, Hanna

    2015-10-01

    Neonaticide is a rare form of homicide. It is generally classed as manslaughter but differs from other forms of homicide in many respects. The factors favouring its occurrence and the legal position of neonaticide in Germany are discussed. The case is presented of a mother who committed five neonaticides within 8 years. While she was a caring mother for her two oldest children, she killed the five subsequent offspring immediately after giving birth. In the scarce literature on neonaticides, a case of multiple offending is particularly rare. Similarities to, and differences from, other cases of neonaticide in the literature are considered. The psychodynamic context of the offences is examined in order to identify contributing features which could be used to help prevent future occurrences. Copyright © 2015 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.

  4. Extranodal posttransplant plasmacytic hyperplasia with subsequent posttransplant plasmacytic malignancy: six-year interval case report and review of the literature.

    PubMed

    Dunphy, Cherie H; Galambos, Csaba; Polski, Jacek M; Evans, H Lance; Gardner, Laura J; Grosso, Leonard E; Montone, Kathleen T

    2002-03-01

    Posttransplant lymphoproliferative disorders (PTLDs) represent a morphologic, immunophenotypic, and genotypic spectrum of disease. Most recently, Knowles et al divided PTLDs into 3 distinct categories: (1) plasmacytic hyperplasia, (2) polymorphic B-cell hyperplasia and polymorphic B-cell lymphoma, and (3) immunoblastic lymphoma and multiple myeloma. Although one form of PTLD may progress to another form, only 1 previous case has been reported in which multiple myeloma developed 14 months after an original diagnosis of plasmacytic hyperplasia. The type of solid organ transplant was not specified in that case. We report a post--cardiac transplant plasmacytic hyperplasia developing 7 years posttransplant. Six years subsequent to the plasmacytic hyperplasia, the patient developed a posttransplant plasmacytic malignancy, supported by morphology, flow cytometric immunophenotyping, and genotypic studies. Since we have no data to support disseminated bony disease or an abnormal serum protein, we have not used the term "multiple myeloma" for this case.

  5. Treatment of ligneous conjunctivitis with amniotic membrane transplantation and topical cyclosporine

    PubMed Central

    Tok, Ozlem Yalcin; Kocaoglu, Fatma Akbas; Tok, Levent; Burcu, Ayse; Ornek, Firdevs

    2012-01-01

    Ligneous conjunctivitis (LC) is a rare form of bilateral chronic recurrent disease in which thick membranes form on the palpebral conjunctiva and other mucosal sites. We report the clinical features and describe the management of two cases. Case 1 was an 8-month-old patient with bilateral membranous conjunctivitis. Case 2 was a 5-year-old patient with unilateral membranous conjunctivitis, esotropia, mechanical ptosis and complicated cataract, and had been treated with a number of medications. Histological investigation of the membrane in both cases showed LC. Treatments with amniotic membrane transplantation and institution of topical cyclosporine have shown good response. There has been complete resolution of the membranes with no recurrence at the end of 40- and 28-month follow-ups, respectively. No treatment related side effects were seen. Thus, it appears that amniotic membrane transplantation and topical cyclosporine are effective alternatives for the treatment of LC. PMID:23202401

  6. [No X-chromosome linked juvenile foveal retinoschisis].

    PubMed

    Pérez Alvarez, M J; Clement Fernández, F

    2002-08-01

    To describe the clinical characteristics of two cases of juvenile foveal retinoschisis in women with an atypical hereditary pattern, no X-chromosome linked. An autosomal recessive inheritance is proposed. Two generations of a family (5 members) in which only two sisters were evaluated. The complete examination of these two cases includes retinography, fluorescein angiography, automated perimetry, color vision testing, electroretinogram, electrooculogram and visually evoked potentials. Comparing our cases with the classic form of X-linked juvenile retinoschisis, they are less severely affected. The best visual acuity and the less disturbed or even normal electroretinogram confirm this fact. We emphasise the existence of isolated plaques of retinal pigment epithelium atrophy with perivascular pigment clumps without foveal schisis in one patient, which could represent an evolved form of this entity. The hereditary foveal juvenile retinoschisis in women suggests an autosomal inheritance (autosomal recessive in our cases) and presents less severe involvement (Arch Soc Esp Oftalmol 2002; 77: 443-448).

  7. Hypertrophic gastropathy with gastric adenocarcinoma: Menetrier's disease and lymphocytic gastritis?

    PubMed Central

    Mosnier, J F; Flejou, J F; Amouyal, G; Gayet, B; Molas, G; Henin, D; Potet, F

    1991-01-01

    Lymphocytic gastritis is a form of gastric inflammation characterised by a pronounced increase in lymphocytes in gastric surface and foveolar epithelium. Lymphocytic gastritis is often associated with endoscopic evidence of 'varioliform gastritis'. Lymphocytic gastritis has recently been reported to be associated with other forms of hypertrophic gastropathies. We present a case of hypertrophic gastropathy with gastric adenocarcinoma, with both Menetrier's disease and lymphocyte gastritis. Immunohistochemical studies showed that the intraepithelial lymphocytes were predominantly alpha/beta T cells as in the normal stomach and not gamma/delta T cells as in coeliac sprue. This case together with the six recently published cases suggests that Menetrier's disease and lymphocytic gastritis may be part of the same disease spectrum. Images Figure 1 Figure 2 PMID:1773969

  8. Anomalous pulmonary venous connection: An underestimated entity.

    PubMed

    Magalhães, Sara P; Moreno, Nuno; Loureiro, Marília; França, Manuela; Reis, Fernanda; Alvares, Sílvia; Ribeiro, Manuel

    2016-12-01

    Anomalous pulmonary venous connection is an uncommon congenital anomaly in which all (total form) or some (partial form) pulmonary veins drain into a systemic vein or into the right atrium rather than into the left atrium. The authors present one case of total anomalous pulmonary venous connection and two cases of partial anomalous pulmonary venous connection, one of supracardiac drainage into the brachiocephalic vein, and the other of infracardiac anomalous venous drainage (scimitar syndrome). Through the presentation of these cases, this article aims to review the main pulmonary venous developmental defects, highlighting the role of imaging techniques in the assessment of these anomalies. Copyright © 2016 Sociedade Portuguesa de Cardiologia. Publicado por Elsevier España, S.L.U. All rights reserved.

  9. Effect of the 80-hour work week on resident case coverage: corrected article.

    PubMed

    Shin, Susanna; Britt, Rebecca; Britt, L D

    2008-07-01

    On July 1, 2003, residency training programs were required to institute restricted duty hours as mandated by the Accreditation Council for Graduate Medical Education. A major concern,voiced by both surgical residents and faculty, was an expectation that this would result in a decrease in operative experience. We hypothesized that implementing restricted duty hours would decrease case coverage by resident trainees. A retrospective study was per formed of operative and endoscopic cases scheduled for a single general surgery practice for a year before and after July 1, 2003. Data collected included operation per formed, number of attending surgeons present, whether a resident was present,and level of resident. From July 2002 to June 2003, there were 1,278 cases scheduled; 890 records were available. From July 2004 to June 2005, there were 1,182 cases scheduled; 960 records were available. Before institution of the restricted duty hours, 24.6% of junior-level (PGY1 and 2) cases, 21.7%of intermediate-level (PGY3) cases, and 6.2% of senior-level (PGY4 and 5) cases were not covered by residents. After restricted duty hours were implemented, 27.3% of junior-level cases,15.9% of intermediate-level cases, and 8.1% of senior-level cases were not covered by residents. Overall 20.8% (185 of 890) and 20.4% (196 of 960) of cases were not covered by residents before and after instituting restricted duty hours, respectively. No difference in case coverage was statistically significant in each category or overall. Restricted duty hours have not affected resident case coverage.

  10. Covariant symplectic structure of the complex Monge-Ampère equation

    NASA Astrophysics Data System (ADS)

    Nutku, Y.

    2000-04-01

    The complex Monge-Ampère equation is invariant under arbitrary holomorphic changes of the independent variables with unit Jacobian. We present its variational formulation where the action remains invariant under this infinite group. The new Lagrangian enables us to obtain the first symplectic 2-form for the complex Monge-Ampère equation in the framework of the covariant Witten-Zuckerman approach to symplectic structure. We base our considerations on a reformulation of the Witten-Zuckerman theory in terms of holomorphic differential forms. The first closed and conserved Witten-Zuckerman symplectic 2-form for the complex Monge-Ampère equation is obtained in arbitrary dimension and for all cases elliptic, hyperbolic and homogeneous. The connection of the complex Monge-Ampère equation with Ricci-flat Kähler geometry suggests the use of the Hilbert action principle as an alternative variational formulation. However, we point out that Hilbert's Lagrangian is a divergence for Kähler metrics and serves as a topological invariant rather than yielding the Euclideanized Einstein field equations. Nevertheless, since the Witten-Zuckerman theory employs only the boundary terms in the first variation of the action, Hilbert's Lagrangian can be used to obtain the second Witten-Zuckerman symplectic 2-form. This symplectic 2-form vanishes on shell, thus defining a Lagrangian submanifold. In its derivation the connection of the second symplectic 2-form with the complex Monge-Ampère equation is indirect but we show that it satisfies all the properties required of a symplectic 2-form for the complex elliptic, or hyperbolic Monge-Ampère equation when the dimension of the complex manifold is 3 or higher. The complex Monge-Ampère equation admits covariant bisymplectic structure for complex dimension 3, or higher. However, in the physically interesting case of n=2 we have only one symplectic 2-form. The extension of these results to the case of complex Monge-Ampère-Liouville equation is also presented.

  11. Reexamining Ground SOF Command and Control: Does One Size Fit All

    DTIC Science & Technology

    2016-12-01

    Case studies covering varying methods of employment of special operations forces in limited contingencies will be utilized. The case studies focus on ...operating environment, much like an open organization. This research examines three case studies including operation JUST CAUSE in Panama, RESTORE HOPE in... case studies , the HQ elements formed around existing homogenous commands and not a Theater Special Operations Command (TSOC) staff with limited

  12. Effect of digital problem-based learning cases on student learning outcomes in ophthalmology courses.

    PubMed

    Kong, Jun; Li, Xiaoyan; Wang, Youdong; Sun, Wei; Zhang, Jinsong

    2009-09-01

    To assess the impact of digital problem-based learning (PBL) cases on student learning in ophthalmology courses. Ninety students were randomly divided into 3 classes (30 students per class). The first class studied under a didactic model. The other 2 classes were divided into 6 groups (10 students per group) and received PBL teaching; 3 groups studied via cases presented in digital form and the others studied via paper-form cases. The results of theoretical and case analysis examinations were analyzed using the chi(2) test. Student performance on the interval practice was analyzed using the Kruskal-Wallis test. Questionnaires were used to evaluate student and facilitator perceptions. Students in the digital groups exhibited better performance in the practice procedures according to tutorial evaluations compared with the other groups (P < .05). The 2 PBL classes had significantly higher mean results of theoretical and case analysis examinations (P < .001), but there was no significant difference between the 2 PBL classes. Ninety-three percent of students in the digital groups (vs 73% in the paper groups) noted that the cases greatly stimulated their interest. Introducing PBL into ophthalmology could improve educational quality and effectiveness. Digital PBL cases stimulate interest and motivate students to further improve diagnosis and problem-handling skills.

  13. Exact solutions for the selection-mutation equilibrium in the Crow-Kimura evolutionary model.

    PubMed

    Semenov, Yuri S; Novozhilov, Artem S

    2015-08-01

    We reformulate the eigenvalue problem for the selection-mutation equilibrium distribution in the case of a haploid asexually reproduced population in the form of an equation for an unknown probability generating function of this distribution. The special form of this equation in the infinite sequence limit allows us to obtain analytically the steady state distributions for a number of particular cases of the fitness landscape. The general approach is illustrated by examples; theoretical findings are compared with numerical calculations. Copyright © 2015. Published by Elsevier Inc.

  14. [Presentation of 2 cases of sudden deafness in patients with sickle-cell anemia and trait].

    PubMed

    García Callejo, F J; Sebastián Gil, E; Morant Ventura, A; Marco Algarra, J

    2002-05-01

    We report two cases of sudden deafness which appeared during vaso-occlusive crisis of a sickle cell anaemia (homozygous form of disease) and a sickle cell trait (heterozygous form) in two males aged sixteen and twenty-two, respectively. A high erythrocyte aggregability and low deformability were proved in both young men. Although hearing disorders have been reported in this disease, a sudden onset is not common. The treatment used was useful in the removal of painful crisis and infections, but deafness did not improve in either of then.

  15. Geometric approach to nuclear pasta phases

    NASA Astrophysics Data System (ADS)

    Kubis, Sebastian; Wójcik, Włodzimierz

    2016-12-01

    By use of the variational methods and differential geometry in the framework of the liquid drop model we formulate appropriate equilibrium equations for pasta phases with imposed periodicity. The extension of the Young-Laplace equation in the case of charged fluid is obtained. The β equilibrium and virial theorem are also generalized. All equations are shown in gauge invariant form. For the first time, the pasta shape stability analysis is carried out. The proper stability condition in the form of the generalized Jacobi equation is derived. The presented formalism is tested on some particular cases.

  16. Structure Analysis of Jungle-Gym-Type Gels by Brownian Dynamics Simulation

    NASA Astrophysics Data System (ADS)

    Ohta, Noriyoshi; Ono, Kohki; Takasu, Masako; Furukawa, Hidemitsu

    2008-02-01

    We investigated the structure and the formation process of two kinds of gels by Brownian dynamics simulation. The effect of flexibility of main chain oligomer was studied. From our results, hard gel with rigid main chain forms more homogeneous network structure than soft gel with flexible main chain. In soft gel, many small loops are formed, and clusters tend to shrink. This heterogeneous network structure may be caused by microgels. In the low density case, soft gel shows more heterogeneity than the high density case.

  17. The longest faun tail forming dreadlocks with underlying spina bifida occulta.

    PubMed

    Brar, Balvinder Kaur; Mahajan, Bharat Bhushan; Mittal, Jyotisterna

    2013-04-15

    Spina bifida is a developmental anomaly characterized by defective closure of the bony encasement of the spinal cord through which the spinal cord and meninges may or may not protrude. We report a rare case of a very long faun tail, which was in the form of a 20 inch long tail originating from the lumbosacral area in a rhomboidal pattern, measuring 10 x 8 inches. The case is being reported for its rare presentation of a 20 inch long faun tail with underlying spina bifida occulta.

  18. Summary of EASM Turbulence Models in CFL3D With Validation Test Cases

    NASA Technical Reports Server (NTRS)

    Rumsey, Christopher L.; Gatski, Thomas B.

    2003-01-01

    This paper summarizes the Explicit Algebraic Stress Model in k-omega form (EASM-ko) and in k-epsilon form (EASM-ke) in the Reynolds-averaged Navier-Stokes code CFL3D. These models have been actively used over the last several years in CFL3D, and have undergone some minor modifications during that time. Details of the equations and method for coding the latest versions of the models are given, and numerous validation cases are presented. This paper serves as a validation archive for these models.

  19. Gunshot residue particles formed by using ammunitions that have mercury fulminate based primers.

    PubMed

    Zeichner, A; Levin, N; Dvorachek, M

    1992-11-01

    Ammunition having mercury fulminate-based primers are commonly manufactured by Eastern Bloc countries and used extensively in the Middle East. Gunshot residue (GSR) particles formed by firing these types of ammunition were examined. It was observed that much lower percentage of mercury-containing GSR particles were found in samples taken from a shooter as compared to the percentage of such particles in samples from cartridge cases. This fact must therefore be taken into account when interpreting case results. A plausible explanation for the results described is proposed.

  20. Bilateral macrodystrophia lipomatosa with syndactyly: a case report and literature review.

    PubMed

    Albright, Steven B; Wolfswinkel, Erik M; Caceres, Kevin J; Weathers, William M; Hollier, Larry H

    2013-01-01

    Macrodystrophia lipomatosa is a rare, non-hereditary form of congenital local gigantism characterised by enlargement and hypertrophy of all mesenchymal tissue components with a disproportionate increase in adipose tissue. This form of macrodactyly has been reported in association with other anomalies including polydactyly, brachydactyly, syndactyly, and symphalangism. We describe a previously unreported case of bilateral upper extremity macrodystrophia lipomatosa with syndactyly in a 23-month-old boy. In this report, we emphasise the importance of establishing a diagnosis with imaging and review the described surgical approaches to treating this difficult condition.

  1. Working Boards in Tertiary Education: Lessons from Three Case Studies. Professional File. Number 25

    ERIC Educational Resources Information Center

    Lang, Daniel W.

    2005-01-01

    There are a number of studies that classify governing boards into different types. Some classifications are based on management form. Some are based on the form in which authority is exercised. Some are based on the form of institution that the board serves. Most of these classifications include "working boards," but few offer a clear…

  2. 27 CFR 26.79 - Inspection or gauge and computation of tax.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... shall: (a) In the case of spirits in packages, prepare a gauge record as provided in § 26.164a in... quantity of spirits described on Form 5110.51, he shall amend and initial the data in part I of the form. The revenue agent shall deliver all copies of Form 5110.51 and any accompanying package gauge record...

  3. 27 CFR 26.79 - Inspection or gauge and computation of tax.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... shall: (a) In the case of spirits in packages, prepare a gauge record as provided in § 26.164a in... quantity of spirits described on Form 5110.51, he shall amend and initial the data in part I of the form. The revenue agent shall deliver all copies of Form 5110.51 and any accompanying package gauge record...

  4. 27 CFR 26.79 - Inspection or gauge and computation of tax.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... shall: (a) In the case of spirits in packages, prepare a gauge record as provided in § 26.164a in... quantity of spirits described on Form 5110.51, he shall amend and initial the data in part I of the form. The revenue agent shall deliver all copies of Form 5110.51 and any accompanying package gauge record...

  5. 27 CFR 26.79 - Inspection or gauge and computation of tax.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... shall: (a) In the case of spirits in packages, prepare a gauge record as provided in § 26.164a in... quantity of spirits described on Form 5110.51, he shall amend and initial the data in part I of the form. The revenue agent shall deliver all copies of Form 5110.51 and any accompanying package gauge record...

  6. 27 CFR 26.79 - Inspection or gauge and computation of tax.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... shall: (a) In the case of spirits in packages, prepare a gauge record as provided in § 26.164a in... quantity of spirits described on Form 5110.51, he shall amend and initial the data in part I of the form. The revenue agent shall deliver all copies of Form 5110.51 and any accompanying package gauge record...

  7. 26 CFR 20.2053-4 - Deduction for claims against the estate.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... defendant in the suit. D's Form 706 is due before a judgment is reached in the case. D's gross estate... Estate (and Generation-Skipping Transfer) Tax Return (Form 706) the current value of the claim or claims... deduction is claimed on Form 706 for a claim against the estate and, during the period described in § 20...

  8. On determinant representations of scalar products and form factors in the SoV approach: the XXX case

    NASA Astrophysics Data System (ADS)

    Kitanine, N.; Maillet, J. M.; Niccoli, G.; Terras, V.

    2016-03-01

    In the present article we study the form factors of quantum integrable lattice models solvable by the separation of variables (SoVs) method. It was recently shown that these models admit universal determinant representations for the scalar products of the so-called separate states (a class which includes in particular all the eigenstates of the transfer matrix). These results permit to obtain simple expressions for the matrix elements of local operators (form factors). However, these representations have been obtained up to now only for the completely inhomogeneous versions of the lattice models considered. In this article we give a simple algebraic procedure to rewrite the scalar products (and hence the form factors) for the SoV related models as Izergin or Slavnov type determinants. This new form leads to simple expressions for the form factors in the homogeneous and thermodynamic limits. To make the presentation of our method clear, we have chosen to explain it first for the simple case of the XXX Heisenberg chain with anti-periodic boundary conditions. We would nevertheless like to stress that the approach presented in this article applies as well to a wide range of models solved in the SoV framework.

  9. [Pathological form in breast cancer: setting and evaluation of a professional pratice].

    PubMed

    Barré, Maxime; Classe, Jean-Marc; Dravet, François; Dupré, Pierre-François; Loussouarn, Delphine; Toquet, Claire; Sagan, Christine

    2009-06-01

    According to national recommendations, the surgical oncologic specimens addressed to a pathology department must have the required clinical information. The objectives of this study are to evaluate the quality of filling out a pathology form used in breast pathology, to specify the nonconformity consequences on breast management, on histology report and to define modes of action in order to obtain an increase in the number of correct pathology forms. It is a prospective study on pathology forms transmitted with tumorectomy for cancers or microcalcifications filled out by three surgeons from the 1st October, 2004 to the 31st April, 2005. Two hundred and fifty-nine pathology forms were analyzed. There were not correctly filled out in a third of the cases. Nonconformity concerns only one preset information in 69% of pathology forms and is variable according to the surgeons (14 to 31%). The chapters least informed are "lesion" and "type of surgery". These nonconformities involve additional work for the pathologist either because the missing information must be found or because the specimen management must be modified. The prefilled pathology form is a guarantee of quality control. In our study, in 70% of cases, they are accurate. To improve this conformity rate, quality improvement plans must be implemented.

  10. Mycelial forms of Coccidioides spp. in the parasitic phase associated to pulmonary coccidioidomycosis with type 2 diabetes mellitus.

    PubMed

    Muñoz-Hernández, B; Martínez-Rivera, M A; Palma Cortés, G; Tapia-Díaz, A; Manjarrez Zavala, M E

    2008-09-01

    Pulmonary coccidioidomycosis shares characteristics with other pulmonary pathologies. In tissue, spherules containing endospores are markers of Coccidioides immitis and C. posadasii infection. Mycelial forms presenting without classical parasitic structures are often misdiagnosed. The study was performed at the National Institute of Respiratory Diseases (INER) of Mexico between September 1991 and June 2005 and analyzed the association between cases, controls, and risk factors, including co-morbidity. A case was defined as any patient who presented mycelial forms and a control as any patient who presented only spherules or no parasitic forms. All patients (n = 44) with pulmonary coccidioidomycosis were diagnosed by culture, histopathology, cytology, and immunology. Type 2 diabetic patients with pulmonary coccidioidomycosis were four times more likely than non-diabetics to develop parasitic mycelial forms (95% confidence interval [CI], 0.85-20.10; P < 0.01). We formulated a comprehensive definition based on the results as follows: patients with pulmonary coccidioidomycosis with an evolution longer than 8 months, cough, hemoptysis, radiological evidence of a cavitary lesion, and type 2 diabetes mellitus, develop parasitic mycelial forms of Coccidioides spp. Based on microscopic images of patient specimens, we propose incorporating mycelial forms into the parasitic phase of Coccidioides spp. in patients with type 2 diabetes mellitus and chronic and cavitary pulmonary coccidioidomycosis.

  11. Tubular forms of papova viruses in human laryngeal papilloma.

    PubMed

    Arnold, W

    1979-01-01

    In two cases of recurrent laryngeal papillomatosis tubular forms of papova viruses could be observed. The same material revealed the close relation between nuclear chromatine and the release of particles, as well as a capsomere like substructure of the virions.

  12. Sixth-Form Projects in Biology: A Case History.

    ERIC Educational Resources Information Center

    Robinson, P. M.; Parker, R. E.

    1981-01-01

    Some of the problems encountered in devising sixth-form projects are discussed and a detailed account given of one project in which a study was made of the effect of onion bulb volatiles on the germination of lettuce seed. (Author)

  13. An Evaluation of Gender Differences in Computer-Based Case Simulations.

    ERIC Educational Resources Information Center

    Scheuneman, Janice Dowd; And Others

    As part of the research leading to the implementation of computer-based case simulations (CCS) for the licensing examinations of the National Board of Medical Examiners, gender differences in performance were studied for one form consisting of 18 cases. A secondary purpose of the study was to note differences in style or approach that might…

  14. Individualization of Instruction: High School Chemistry - A Case Study.

    ERIC Educational Resources Information Center

    Altieri, Donald; Becht, Paul

    This publication contains information on the individualization of instruction in high school chemistry in the form of a case study. The subject of the case study is the P. K. Yonge Laboratory School of the University of Florida, Gainesville. The instructional model, however, was also field-tested in 18 schools during 1971-72 and 1972-73. The…

  15. Therapist concerns and process issues in grappling with functional autobiographical amnesia.

    PubMed

    Tripathi, Ravikesh; Bharath, Srikala; Desai, Geetha; Mehrotra, Seema

    2013-07-01

    Dissociative amnesia is relatively rare form of the dissociative disorder. This paper aims at describing the salient features of a case of functional autobiographical amnesia in a young adult and the approach adopted in the psychological management of this case. The case highlights concerns of the therapist at various stages of the therapy process.

  16. Applications of a Case Library of Technology Integration Stories for Teachers

    ERIC Educational Resources Information Center

    Wang, Feng-Kwei; Jonassen, David H.; Strobel, Johannes; Cernusca, Dawn

    2003-01-01

    Stories are the most natural form of communication and learning among humans. In this paper, we describe how we have designed and implemented an case library of technology integration stories to support pre-service and in-service teachers learning how to integrate technologies into their teaching. The case library was built using the artificial…

  17. Singularly Perturbed Equations in the Critical Case.

    DTIC Science & Technology

    1980-02-01

    asymptotic properties of the differential equation (1) in the noncritical case (all ReXi (t) ɘ) . We will consider the critical case (k 0) ; the...the inequality (3), that is, ReXi (t,a) < 0 (58) The matrix ca(t,a) , consisting of the eigenvectors corresponding to w 0 , now has the form I (P -(t

  18. Task-Based Language Teaching with Smartphones: A Case Study in Pakistan

    ERIC Educational Resources Information Center

    Rashid, Shaista; Cunningham, Una; Watson, Kevin

    2017-01-01

    Integration of technology in task-based language teaching (TBLT) has long been a source of attraction for language teachers (Pierson, 2015). In the case of developing countries, such as Pakistan, mobile phones are the modern form of technology commonly available at low cost to individuals as well as institutions. The present descriptive case study…

  19. A Case Study of Autonomy and Motivation in a Student-Led Game Development Project

    ERIC Educational Resources Information Center

    Prigmore, M.; Taylor, R.; De Luca, D.

    2016-01-01

    This paper presents the findings of an exploratory case study into the relationship between student autonomy and motivation in project based learning, using Self-Determination Theory (SDT) to frame the investigation. The case study explores how different forms of motivation affect the students' response to challenges and their intention to…

  20. Methodological Considerations for an Evolving Model of Institutional Research.

    ERIC Educational Resources Information Center

    Jones, Timothy B.; Essien-Barrett, Barbara; Gill, Peggy B.

    A multi-case study was used in the self-study of three programs within an academic department of a mid-sized Southern university. Multi-case methodology as a form of self-study encourages a process of self-renewal and programmatic change as it defines an active stakeholder role. The participants in the three case studies were university faculty…

  1. "It's All Connected!" Nursing Students' Experiences of a New Form of Case Seminar Integrating Medical and Nursing Science

    ERIC Educational Resources Information Center

    Turunen Olsson, Pernilla; Weurlander, Maria; Mattiasson, Anne-Cathrine; Wärn Hede, Gunnel; Panagiotidis, Georgios; Broberger, Eva; Hult, Håkan; Wernerson, Annika

    2016-01-01

    Traditionally, nursing students learn medical subjects and nursing separately, which makes it difficult to develop an integrated understanding. This study aimed to explore nursing students' experiences of participating in a case seminar integrating medical and nursing sciences and if, and how, it contributed to their learning. A case seminar…

  2. Racism in the Classroom: Case Studies.

    ERIC Educational Resources Information Center

    Duhon, Gwendolyn M.

    This book presents 20 cases that address racism in one form or another. Many of the cases are from actual experience. They are intended to bring out actual or possible solutions so that student teachers, novice teachers, and seasoned teachers can find ideas for solving racist problems in their classrooms. The first part focuses on the early years,…

  3. A benefit/risk approach towards selecting appropriate pharmaceutical dosage forms - an application for paediatric dosage form selection.

    PubMed

    Sam, Tom; Ernest, Terry B; Walsh, Jennifer; Williams, Julie L

    2012-10-05

    The design and selection of new pharmaceutical dosage forms involves the careful consideration and balancing of a quality target product profile against technical challenges and development feasibility. Paediatric dosage forms present particular complexity due to the diverse patient population, patient compliance challenges and safety considerations of this vulnerable population. This paper presents a structured framework for assessing the comparative benefits and risks of different pharmaceutical design options against pre-determined criteria relating to (1) efficacy, (2) safety and (3) patient access. This benefit/risk framework has then been applied to three hypothetical, but realistic, scenarios for paediatric dosage forms in order to explore its utility in guiding dosage form design and formulation selection. The approach allows a rigorous, systematic and qualitative assessment of the merits and disadvantages of each dosage form option and helps identify mitigating strategies to modify risk. The application of a weighting and scoring system to the criteria depending on the specific case could further refine the analysis and aid decision-making. In this paper, one case study is scored for illustrative purposes. However, it is acknowledged that in real development scenarios, the generation of actual data considering the very specific situation for the patient/product/developer would come into play to drive decisions on the most appropriate dosage form strategy. Copyright © 2012 Elsevier B.V. All rights reserved.

  4. Design criteria monograph for pressurized metal cases

    NASA Technical Reports Server (NTRS)

    1972-01-01

    Organiation and presentation of data pertaining to design of solid propellant rocket engine cases are discussed. Design criteria are presented in form of monograph based on accumulated experience and knowledge. Improvements in reliability, cost effectiveness, and engine efficiency are stressed.

  5. Craniofacial duplication (diprosopus): report of a case with a review of the literature.

    PubMed

    Amr, S S; Hammouri, M F

    1995-01-01

    A case of craniofacial duplication (diprosopus) is presented. Details on this rare form of conjoined twins are described, and the proposed theories of its embryogenesis are discussed with brief review of the pertinent literature.

  6. Incubation Period and Early Natural History Events of the Acute Form of Paracoccidioidomycosis: Lessons from Patients with a Single Paracoccidioides spp. Exposure.

    PubMed

    Buccheri, Renata; Khoury, Zarifa; Barata, Luis Carlos Barradas; Benard, Gil

    2016-06-01

    Several aspects of the natural history of paracoccidioidomycosis are still poorly understood. Different from the most prevalent, chronic form of the disease, the acute form represents a continuum from the initial respiratory infection to the full-blown disease, thus providing an opportunity to elucidate the pathogenesis of the early phase of this mycosis. We describe, for the first time, two patients with a single time point exposure to Paracoccidioides spp., for whom we were able to determine the time lapsed between exposure to the fungus Paracoccidioides spp. and the onset of signs and symptoms. In case 1, the pulmonary infection was unapparent, and the first manifestations of the acute/subacute form of the disease presented 4 months after Paracoccidioides spp. In case 2, self-limited, non-specific respiratory and systemic symptoms presented 45 days after infection. Thus, our patients confirm that, within a few weeks of infection, Paracoccidioides spp. affects the pulmonary lymphatic system and initially causes no or mild-to-moderate self-limited symptoms, eventually causing abnormalities on a chest X-ray, all of which spontaneously subside. These cases provide some insight into the natural history of this mycosis, the extent of the host exposure to the fungus, and the determination of its incubation period.

  7. [A case with apraxia of tool use: selective inability to form a hand posture for a tool].

    PubMed

    Hayakawa, Yuko; Fujii, Toshikatsu; Yamadori, Atsushi; Meguro, Kenichi; Suzuki, Kyoko

    2015-03-01

    Impaired tool use is recognized as a symptom of ideational apraxia. While many studies have focused on difficulties in producing gestures as a whole, using tools involves several steps; these include forming hand postures appropriate for the use of certain tool, selecting objects or body parts to act on, and producing gestures. In previously reported cases, both producing and recognizing hand postures were impaired. Here we report the first case showing a selective impairment of forming hand postures appropriate for tools with preserved recognition of the required hand postures. A 24-year-old, right-handed man was admitted to hospital because of sensory impairment of the right side of the body, mild aphasia, and impaired tool use due to left parietal subcortical hemorrhage. His ability to make symbolic gestures, copy finger postures, and orient his hand to pass a slit was well preserved. Semantic knowledge for tools and hand postures was also intact. He could flawlessly select the correct hand postures in recognition tasks. He only demonstrated difficulties in forming a hand posture appropriate for a tool. Once he properly grasped a tool by trial and error, he could use it without hesitation. These observations suggest that each step of tool use should be thoroughly examined in patients with ideational apraxia.

  8. Clinical forms of actinic keratosis and levels of dysplasia of the epidermis.

    PubMed

    Oshyvalova, Olena O; Kaliuzhna, Lydia D; Kropelnytskyi, Vladislav O

    Introduction: Actinic keratosis (AK) is precancerous skin lesion that occurs in the sun-exposedskin areas characterized by local intraepidermal dysplasia of different severity (KIN I, KIN II and KIN III). The aim of this research was to study distribution patterns and morphological features of AK histological types. Materials and Methods: The study included skin biopsy material from 68 patients with different clinical forms of AK. The diagnosis of AK was histologically confirmed in 100% of cases. Results: There were 63.21% of men and 36.8% of women among all patients with AK. The average age of patients was 73.3 ± 8.3.The most common clinico-histological forms of actinic keratosis were typical (41.2%), hypertrophic (16.2%), atrophic (14.7%) and pigmentary (11.7%), bowenoid (8.8%), acantholytic (7.4%). Among the rate of epidermal dysplasia there diagnosed cases of KIN І (50%), KIN ІІ (36.8%) and KIN III (13.2%). Conclusions: It was found a direct correlation between KIN I and typical and pigment forms of AK, KIN II and hypertrophic and bowenoid forms of AK.

  9. Formation, Physicochemical Characterization, and Thermodynamic Stability of the Amorphous State of Drugs and Excipients.

    PubMed

    Martino, Piera Di; Magnoni, Federico; Peregrina, Dolores Vargas; Gigliobianco, Maria Rosa; Censi, Roberta; Malaj, Ledjan

    2016-01-01

    Drugs and excipients used for pharmaceutical applications generally exist in the solid (crystalline or amorphous) state, more rarely as liquid materials. In some cases, according to the physicochemical nature of the molecule, or as a consequence of specific technological processes, a compound may exist exclusively in the amorphous state. In other cases, as a consequence of specific treatments (freezing and spray drying, melting and co-melting, grinding and compression), the crystalline form may convert into a completely or partially amorphous form. An amorphous material shows physical and thermodynamic properties different from the corresponding crystalline form, with profound repercussions on its technological performance and biopharmaceutical properties. Several physicochemical techniques such as X-ray powder diffraction, thermal methods of analysis, spectroscopic techniques, gravimetric techniques, and inverse gas chromatography can be applied to characterize the amorphous form of a compound (drug or excipient), and to evaluate its thermodynamic stability. This review offers a survey of the technologies used to convert a crystalline solid into an amorphous form, and describes the most important techniques for characterizing the amorphous state of compounds of pharmaceutical interest.

  10. Die Deformation Measurement System during Sheet Metal Forming

    NASA Astrophysics Data System (ADS)

    Funada, J.; Takahashi, S.; Fukiharu, H.

    2011-08-01

    In order to reduce affection to the earth environment, it is necessary to lighten the vehicles. For this purpose, high tensile steels are applied. Because of high strength, high forming force is required for producing automotive sheet metal parts. In this situation, since the dies are elastic, they are deformed during forming parts. For reducing die developing period, sheet metal forming simulation is widely applied. In the numerical simulation, rigid dies are usually used for shortening computing time. It means that the forming conditions in the actual forming and the simulation are different. It will make large errors in the results between actual forming and simulation. It can be said that if contact pressure between dies and a sheet metal in the simulation can be reproduced in the actual forming, the differences of forming results between them can also been reduced. The basic idea is to estimate die shape which can produce the same distribution as computed from simulation with rigid dies. In this study, die deformation analyses with Finite Element Method as basic technologies are evaluated. For example, simple shape and actual dies elastic contact problems were investigated. The contact width between simple shape dies was investigated. The computed solutions were in good agreement with experimental results. The one case of the actual dies in two cases was also investigated. Bending force was applied to the blank holder with a mechanical press machine. The methodology shown with applying inductive displacement sensor for measuring die deformation during applying force was also proposed.

  11. A case of Munchausen syndrome by proxy with subsequent suicide of the mother.

    PubMed

    Vennemann, B; Perdekamp, M Grosse; Weinmann, W; Faller-Marquardt, M; Pollak, S; Brandis, M

    2006-05-10

    Munchausen syndrome by proxy is a subtle and difficult to diagnose form of child abuse in which the carer (usually the mother) simulates, manipulates or produces symptoms of illness in the victim. In most cases the detrimental effect is caused by applying foreign substances or by airway obstruction. In the presented case a 20-month-old girl developed a spreading soft-tissue infection resistant to treatment on the left upper arm after vaccination, which required a number of surgical interventions. Repeatedly, microorganisms from the intestinal flora were isolated from the wound secretion. After the girl suffered respiratory and circulatory arrest, which required resuscitation measures, chemical toxicological tests revealed not medically prescribed benzodiazepines in serum and urine. When the mother, a trained nurse, was confronted with the allegation to have manipulated the symptoms of the illness she committed suicide. The forensic autopsy of the suicide produced numerous hints suggesting chronic self-damaging behaviour described as Munchausen syndrome. This case shows a number of manipulation forms with the maintenance of a chronic skin and soft tissue infection belonging to the rarer forms of inflicting damage to the child. It also illustrates that confrontation with the allegation of Munchausen syndrome by proxy creates a very stressful emotional situation that may lead to a suicidal act.

  12. Peripheral dysgraphia characterized by the co-occurrence of case substitutions in uppercase and letter substitutions in lowercase writing.

    PubMed

    Di Pietro, M; Schnider, A; Ptak, R

    2011-10-01

    Patients with peripheral dysgraphia due to impairment at the allographic level produce writing errors that affect the letter-form and are characterized by case confusions or the failure to write in a specific case or style (e.g., cursive). We studied the writing errors of a patient with pure peripheral dysgraphia who had entirely intact oral spelling, but produced many well-formed letter errors in written spelling. The comparison of uppercase print and lowercase cursive spelling revealed an uncommon pattern: while most uppercase errors were case substitutions (e.g., A - a), almost all lowercase errors were letter substitutions (e.g., n - r). Analyses of the relationship between target letters and substitution errors showed that errors were neither influenced by consonant-vowel status nor by letter frequency, though word length affected error frequency in lowercase writing. Moreover, while graphomotor similarity did not predict either the occurrence of uppercase or lowercase errors, visuospatial similarity was a significant predictor of lowercase errors. These results suggest that lowercase representations of cursive letter-forms are based on a description of entire letters (visuospatial features) and are not - as previously found for uppercase letters - specified in terms of strokes (graphomotor features). Copyright © 2010 Elsevier Srl. All rights reserved.

  13. Severe invasive listeriosis--case report.

    PubMed

    Teodor, Andra; Teodor, D; Miftode, Egidia; Prisăcaru, D; Leca, Daniela; Petrovici, Cristina; Dorneanu, Olivia; Dorobăt, Carmen-Mihaela

    2012-01-01

    Listeriosis is a rare food borne infection which, in the invasive form, presents as bloodstream infection, central nervous system infection, materno-fetal infection, or focal infection. Certain immunosuppressive conditions have been identified as risk factors for severe invasive disease. The invasive forms of listeriosis are associated with a high case fatality rate. We present the case of a 62-year-old male with an unremarkable medical history admitted to the Iasi Infectious Diseases Hospital for fever. headache, ataxia, and diplopia. Physical examination revealed high temperature, confusion, relative bradycardia, and signs of meningeal irritation. Laboratory test showed leukocyt osis with neutrophilia. pathological CSF findings (high WBC count with predominance of neutrophils, low glucose and high protein levels), increased liver enzymes (ALAT, ASAT, AP, gammaGT), and important renal impairment (normal levels at presentation). No abnormalities at chest x-ray, cranial CT and abdominal ultrasound. CSF and blood cultures were positive for Listeria monocytogenes. Under antibiotics (ampicillin and ciprofloxacin), the course was marked by respiratory failure requiring mechanical ventilation, coma, hypotension, tachycardia. and death 12 days after admission. The particularity of this case consists in the association of the two classical forms of invasive listeriosis, meningitis and bacteriemia, with a focal infection. acute hepatitis, and a course marked by multiple organ dysfunction syndromes and exitus in a previously apparently healthy individual.

  14. MALIGNANT PLEURAL MESOTHELIOMA TREATED IN CLINIC FOR PULMONARY DISEASES AND TUBERCULOSIS “PODHRASTOVI” IN TEN-YEAR PERIOD (FROM 1998 TO 2007)

    PubMed Central

    Čukić, Vesna; Ustamujić, Aida; Lovre, VLAdimir; Žutić, Hasan; Genjac, Sadika; Mašić - Zečević, Mína

    2008-01-01

    Malignant pleural mesothelioma (MPM) is the most common primary malign tumour of pleura. The aim of this study was to evaluate cases of MPM diagnosed and treated in Clinic for Pulmonary Diseases and Tuberculosis “Podhrastovi” during ten-year period (1998-2007). Study is retrospective. The patients were analysed according to age, sex, histopathologic type of the tumour, cantonal distribution in Federation of Bosnia and Herzegovina and regimen of treatment. MPM presented 0,72% (0-1,56% per year) of all hospitalised malignant patients, and the greatest number of registered cases was in the year of 2007. The series included 16 male (57,14%) and 12 female (42,86%). Cases over 64 years old were the most frequent (14-50%) than 45-54 years (7--25%). Histopathology types of hospitalised cases of MPM: epitheloid form (8- 28,57%); sarcomatoid form (2- 7,14 %); other forms (18-64,29%). The most patients came from Canton Sarajevo (12-42,86%); ZE-DO canton (8-28,57%) and the UNA-SANA canton (5-17,86%). The therapy applied: chemotherapy (11-39,29%); radiotherapy (3-10,71%); chemotherapy + radiotherapy (4-14,29%); symptomatic therapy (10-35,71 %). PMID:19125709

  15. Abel's theorem in the noncommutative case

    NASA Astrophysics Data System (ADS)

    Leitenberger, Frank

    2004-03-01

    We define noncommutative binary forms. Using the typical representation of Hermite we prove the fundamental theorem of algebra and we derive a noncommutative Cardano formula for cubic forms. We define quantized elliptic and hyperelliptic differentials of the first kind. Following Abel we prove Abel's theorem.

  16. 32 CFR Appendix A to Part 636 - References

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... INVESTIGATIONS MOTOR VEHICLE TRAFFIC SUPERVISION (SPECIFIC INSTALLATIONS) Pt. 636, App. A Appendix A to Part 636... 3946, Military Police Traffic Accident Report DA Form 3975, Military Police Report DD Form 1920... Understanding, Subject: Seizure of Assets for Administrative Forfeiture in Drug Related Cases. ...

  17. 32 CFR Appendix A to Part 636 - References

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... INVESTIGATIONS MOTOR VEHICLE TRAFFIC SUPERVISION (SPECIFIC INSTALLATIONS) Pt. 636, App. A Appendix A to Part 636... 3946, Military Police Traffic Accident Report DA Form 3975, Military Police Report DD Form 1920... Understanding, Subject: Seizure of Assets for Administrative Forfeiture in Drug Related Cases. ...

  18. [A case of groove pancreatitis (segmental form) presented with obstructive jaundice associated with pancreatobiliary maljunction].

    PubMed

    Hiramatsu, Kiyoshi; Ito, Takaaki; Kaburagi, Daisuke; Arai, Riki; Maruyama, Hideki; Naganuma, Atsushi; Kato, Kenji

    2008-09-01

    A 52-year-old-man was admitted to our hospital for obstructive jaundice. Percutaneous transhepatic cholangio drainage (PTCD) and endscopic retrograde cholangiopancreatography (ERCP) were performed, and pointed out stenosis of lower common bile duct (CBD) and pancreatobiliary maljunction. Brushing cytology of this lesion was negative for malignancy. CT and MRI revealed chronic inflammatory change in groove lesion with no mass formation suggesting tumor. So we diagnosed groove pancreatitis (segmental form) associated with pancreatobiliary maljunction, and operation (resection of the bile duct and biliary reconstruction by Roux-en-Y) was done. Resected specimen was revealed stenosis of the bile duct formed by fibrous tissue with no malignancy compatible to groove pancreatitis pathologically. This is first reported case of groove pancreatits associated with pancreatobiliary maljunction.

  19. Severe Cutaneous Drug Reactions: Do Overlapping Forms Exist?

    PubMed

    Horcajada-Reales, C; Pulido-Pérez, A; Suárez-Fernández, R

    2016-01-01

    Acute generalized exanthematous pustulosis, Stevens-Johnson syndrome, toxic epidermal necrolysis, and drug reaction with eosinophilia and systemic symptoms are all severe hypersensitivity reactions to medications. While each of these reactions is a well-established entity with specific diagnostic criteria, clinicians see cases that fulfill criteria for more than one form, prompting discussion on the possibility of combined forms. Such overlapping clinical pictures meeting the criteria for 2 conditions have thus become a topic of debate in dermatology in recent years. We describe 2 patients with cutaneous drug reactions having the characteristics of both acute generalized exanthematous pustulosis and Stevens-Johnson syndrome -toxic epidermal necrolysis. We also review previously published cases and current thinking on such overlapping conditions. Copyright © 2015 Elsevier España, S.L.U. and AEDV. All rights reserved.

  20. Poisson structure of dynamical systems with three degrees of freedom

    NASA Astrophysics Data System (ADS)

    Gümral, Hasan; Nutku, Yavuz

    1993-12-01

    It is shown that the Poisson structure of dynamical systems with three degrees of freedom can be defined in terms of an integrable one-form in three dimensions. Advantage is taken of this fact and the theory of foliations is used in discussing the geometrical structure underlying complete and partial integrability. Techniques for finding Poisson structures are presented and applied to various examples such as the Halphen system which has been studied as the two-monopole problem by Atiyah and Hitchin. It is shown that the Halphen system can be formulated in terms of a flat SL(2,R)-valued connection and belongs to a nontrivial Godbillon-Vey class. On the other hand, for the Euler top and a special case of three-species Lotka-Volterra equations which are contained in the Halphen system as limiting cases, this structure degenerates into the form of globally integrable bi-Hamiltonian structures. The globally integrable bi-Hamiltonian case is a linear and the SL(2,R) structure is a quadratic unfolding of an integrable one-form in 3+1 dimensions. It is shown that the existence of a vector field compatible with the flow is a powerful tool in the investigation of Poisson structure and some new techniques for incorporating arbitrary constants into the Poisson one-form are presented herein. This leads to some extensions, analogous to q extensions, of Poisson structure. The Kermack-McKendrick model and some of its generalizations describing the spread of epidemics, as well as the integrable cases of the Lorenz, Lotka-Volterra, May-Leonard, and Maxwell-Bloch systems admit globally integrable bi-Hamiltonian structure.

  1. Al Qaeda in the Indian Subcontinent (AQIS): An Al Qaeda Affiliate Case Study

    DTIC Science & Technology

    2017-10-01

    conduct this assessment, CNA used a comparative methodology that included eight case studies on groups affiliated or associated with Al-Qaeda. These case...Case Study Pamela G. Faber and Alexander Powell October 2017 This work was performed under Federal Government Contract No. N00014-16-D-5003. Copyright...Director Center for Stability and Development Center for Strategic Studies REPORT DOCUMENTATION PAGE Form ApprovedOMB No. 0704-0188 Public reporting burden

  2. Trichotillomania in a dementia case

    PubMed Central

    Caixeta, Leonardo; Lopes, Danielly Bandeira

    2011-01-01

    We report an 87-year-old male case of hair pulling associated with a white-matter vascular dementia (Binswanger’s disease). Trichotillomania in our case did not resolve using mirtazapine or anticholinesterasic medication. Trichotillomania seems to be related to a form of perseveration associated with dementia. The findings in this case suggest the abnormality involving white matter in the pathogenesis of trichotillomania, may constitute a defect in connectivity in the right frontal-subcortical circuit. PMID:29213722

  3. Corneal ulcer due to a rare coelomycetes fungus Chaetomium strumarium: Case report and global review of Chaetomium keratomycosis.

    PubMed

    Reddy, Mamatha; Venugopal, Ramya; Prakash, Peralam Yegneswaran; Kamath, Yogish Subraya

    2017-09-01

    We present a rare case of corneal ulcer caused by a species of a coelomycetes fungus, Chaetomium strumarium. This fungal genus is a rare causative agent of keratomycosis, with only a handful of cases reported. The clinical presentation, investigative techniques, and preliminary management of our patient are reported. The cases reported in global literature are also summarized in a tabular form in the discussion.

  4. Let’s agree on the casing of Lidar

    USGS Publications Warehouse

    Deering, Carol; Stoker, Jason M.

    2014-01-01

    Is it lidar, Lidar, LiDAR, LIDAR, LiDar, LiDaR, or liDAR? A comprehensive review of the scientific/technical literature reveals seven different casings of this short form for light detection and ranging. And there could be more.

  5. Cow Dung Ingestion and Inhalation Dependence: A Case Report

    ERIC Educational Resources Information Center

    Khairkar, Praveen; Tiple, Prashant; Bang, Govind

    2009-01-01

    Although abuse of several unusual inhalants had been documented, addiction to cow dung fumes or their ashes has not been reported in medical literature as yet. We are reporting a case of cow dung dependence in ingestion and inhalational form.

  6. An ontological case base engineering methodology for diabetes management.

    PubMed

    El-Sappagh, Shaker H; El-Masri, Samir; Elmogy, Mohammed; Riad, A M; Saddik, Basema

    2014-08-01

    Ontology engineering covers issues related to ontology development and use. In Case Based Reasoning (CBR) system, ontology plays two main roles; the first as case base and the second as domain ontology. However, the ontology engineering literature does not provide adequate guidance on how to build, evaluate, and maintain ontologies. This paper proposes an ontology engineering methodology to generate case bases in the medical domain. It mainly focuses on the research of case representation in the form of ontology to support the case semantic retrieval and enhance all knowledge intensive CBR processes. A case study on diabetes diagnosis case base will be provided to evaluate the proposed methodology.

  7. Report of 457 sporotrichosis cases from Jilin province, northeast China, a serious endemic region.

    PubMed

    Song, Y; Li, S-S; Zhong, S-X; Liu, Y-Y; Yao, L; Huo, S-S

    2013-03-01

    Most reported sporotrichosis cases came from South American countries, the USA, India and Japan. This mycosis is also endemic in Northeast China. However, the situation is not clear for international researchers due to lack of large series reported in English. To report and analyse 457 sporotrichosis cases. Retrospective study of 457 cases of sporotrichosis diagnosed by fungal culture at the First Hospital of Jilin University from 1 January 2007 to 31 December 2009. In this series, the male: female ratio was 1:1.42. Mean age was 41.2 years. Cases from age group 51-60 years accounted for most of the cases (22.54%). A total of 434 patients lived in rural areas (94.97%). The onset of symptoms in 67.61% cases happened in cold seasons (winter and spring). History of trauma presented in 133 cases (29.1%). The mean duration of the symptoms before the presentation was 6.41 months. A total of 190 (41.58%) showed lymphocutaneous form, 252 patients (55.14%) showed fixed form, 8 patients (1.75%) showed disseminated cutaneous sporotrichosis and the clinical form of 7 patients (1.53%) could not be defined. Extremities and nodules were the most frequently involved sites and founded manifestation. Main histopathology findings were suppurative granuloma, tuberculoid granuloma and mixed inflammatory granuloma. A total of 75 cases (19.74%) had fungal elements revealed by Periodic Acid-Schiff staining. Patients responded well to potassium iodide (KI), itraconazole, terbinafine and combinations of these agents with a mean course of 2.17 months to resolve. As the first report of a large series of sporotrichosis cases from China to be published in English literature, our study indicated a serious sporotrichosis endemic situation in Jilin province, Northeast China, with epidemiological and clinical characteristics similar to those of previous Chinese reports, but different from those in other countries. KI, itraconazole and terbinafine are effective for the treatment. © 2011 The Authors. Journal of the European Academy of Dermatology and Venereology © 2011 European Academy of Dermatology and Venereology.

  8. Towards leprosy elimination by 2020: forecasts of epidemiological indicators of leprosy in Corrientes, a province of northeastern Argentina that is a pioneer in leprosy elimination

    PubMed Central

    de Odriozola, Elisa Petri; Quintana, Ana María; González, Victor; Pasetto, Roque Antonio; Utgés, María Eugenia; Bruzzone, Octavio Augusto; Arnaiz, María Rosa

    2017-01-01

    BACKGROUND Corrientes, a province of northeastern Argentina with endemic leprosy, has improved its epidemiological indicators, however, a study of the dynamics over time is lacking. OBJECTIVES We analysed data of 1308 leprosy patients between 1991 to 2014, and the forecast for 2020. METHODS Descriptive statistics and stepwise Bayesian model selection were performed. Forecasts were made using the median of 100,000 projections using the parameters calculated via Monte Carlo methods. RESULTS We found a decreasing number of new leprosy cases (-2.04 cases/year); this decrease is expected to continue by an estimated 20.28 +/- 10.00 cases by 2020, evidenced by a sustained decline in detection rate (from 11 to 2.9/100,000 inhabitants). Age groups that were most affected were 15-44 (40.13%) and 45-64 (38.83%) year olds. Multibacillary forms (MB) predominated (70.35%) and while gradually declining, between 10 and 30% developed disability grade 2 (DG2) (0.175 (0.110 - 0.337) DG2/MB cases), with a time delay between 0 to 15 years (median = 0). The proportion of MB clinic forms and DG2 increased and will continuously increase in the short term (0.036 +/- 0.018 logit (MB/total of cases). MAIN CONCLUSIONS Corrientes is on the way to eliminating leprosy by 2020, however the increased proportion of MB clinical forms and DG2 signals a warning for disease control efforts. PMID:28591402

  9. Towards leprosy elimination by 2020: forecasts of epidemiological indicators of leprosy in Corrientes, a province of northeastern Argentina that is a pioneer in leprosy elimination.

    PubMed

    Odriozola, Elisa Petri de; Quintana, Ana María; González, Victor; Pasetto, Roque Antonio; Utgés, María Eugenia; Bruzzone, Octavio Augusto; Arnaiz, María Rosa

    2017-06-01

    Corrientes, a province of northeastern Argentina with endemic leprosy, has improved its epidemiological indicators, however, a study of the dynamics over time is lacking. We analysed data of 1308 leprosy patients between 1991 to 2014, and the forecast for 2020. Descriptive statistics and stepwise Bayesian model selection were performed. Forecasts were made using the median of 100,000 projections using the parameters calculated via Monte Carlo methods. We found a decreasing number of new leprosy cases (-2.04 cases/year); this decrease is expected to continue by an estimated 20.28 +/- 10.00 cases by 2020, evidenced by a sustained decline in detection rate (from 11 to 2.9/100,000 inhabitants). Age groups that were most affected were 15-44 (40.13%) and 45-64 (38.83%) year olds. Multibacillary forms (MB) predominated (70.35%) and while gradually declining, between 10 and 30% developed disability grade 2 (DG2) (0.175 (0.110 - 0.337) DG2/MB cases), with a time delay between 0 to 15 years (median = 0). The proportion of MB clinic forms and DG2 increased and will continuously increase in the short term (0.036 +/- 0.018 logit (MB/total of cases). Corrientes is on the way to eliminating leprosy by 2020, however the increased proportion of MB clinical forms and DG2 signals a warning for disease control efforts.

  10. Zwischen Gesetz und Fall. Mutmassungen uber Typologien als Padagogische Wissensform (Between General Law and the Individual Case. Conjectures Concerning Typologies as a Form of Pedagogical Knowledge).

    ERIC Educational Resources Information Center

    Herzog, Walter

    2003-01-01

    Considers the mediation between scientific knowledge and practical action as a crucial feature of professional teaching. Investigates the assumption that typologies represent a form of knowledge which can bridge the gap between theory and practice. Differentiates between two forms of typological thinking and discusses reservations concerning…

  11. 29 CFR 2520.104-48 - Alternative method of compliance for model simplified employee pensions-IRS Form 5305-SEP.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... employee pensions-IRS Form 5305-SEP. 2520.104-48 Section 2520.104-48 Labor Regulations Relating to Labor... compliance for model simplified employee pensions—IRS Form 5305-SEP. Under the authority of section 110 of... Security Act of 1974 in the case of a simplified employee pension (SEP) described in section 408(k) of the...

  12. Reconciling Hierarchical and Edge Organizations: 9-11 Revisited

    DTIC Science & Technology

    2014-06-01

    the hierarchical structure, despite claiming to be networked. Hence, our research asks whether these two archetypal forms can be reconciled with one...asks whether these two archetypal forms can be reconciled with one another. By revisiting a case study of the events of September 11th, 2001...organizational form best suited to network-centric operations. Drawing on Mintzberg’s (1979) work on organizational archetypes , five classic organizational

  13. Readability and Content Assessment of Informed Consent Forms for Medical Procedures in Croatia

    PubMed Central

    Vučemilo, Luka; Borovečki, Ana

    2015-01-01

    Background High quality of informed consent form is essential for adequate information transfer between physicians and patients. Current status of medical procedure consent forms in clinical practice in Croatia specifically in terms of the readability and the content is unknown. The aim of this study was to assess the readability and the content of informed consent forms for diagnostic and therapeutic procedures used with patients in Croatia. Methods 52 informed consent forms from six Croatian hospitals on the secondary and tertiary health-care level were tested for reading difficulty using Simple Measure of Gobbledygook (SMOG) formula adjusted for Croatian language and for qualitative analysis of the content. Results The averaged SMOG grade of analyzed informed consent forms was 13.25 (SD 1.59, range 10–19). Content analysis revealed that informed consent forms included description of risks in 96% of the cases, benefits in 81%, description of procedures in 78%, alternatives in 52%, risks and benefits of alternatives in 17% and risks and benefits of not receiving treatment or undergoing procedures in 13%. Conclusions Readability of evaluated informed consent forms is not appropriate for the general population in Croatia. The content of the forms failed to include in high proportion of the cases description of alternatives, risks and benefits of alternatives, as well as risks and benefits of not receiving treatments or undergoing procedures. Data obtained from this research could help in development and improvement of informed consent forms in Croatia especially now when Croatian hospitals are undergoing the process of accreditation. PMID:26376183

  14. Molecular approach to genetic and epigenetic pathogenesis of early-onset colorectal cancer

    PubMed Central

    Tezcan, Gulcin; Tunca, Berrin; Ak, Secil; Cecener, Gulsah; Egeli, Unal

    2016-01-01

    Colorectal cancer (CRC) is the third most frequent cancer type and the incidence of this disease is increasing gradually per year in individuals younger than 50 years old. The current knowledge is that early-onset CRC (EOCRC) cases are heterogeneous population that includes both hereditary and sporadic forms of the CRC. Although EOCRC cases have some distinguishing clinical and pathological features than elder age CRC, the molecular mechanism underlying the EOCRC is poorly clarified. Given the significance of CRC in the world of medicine, the present review will focus on the recent knowledge in the molecular basis of genetic and epigenetic mechanism of the hereditary forms of EOCRC, which includes Lynch syndrome, Familial CRC type X, Familial adenomatous polyposis, MutYH-associated polyposis, Juvenile polyposis syndrome, Peutz-Jeghers Syndrome and sporadic forms of EOCRC. Recent findings about molecular genetics and epigenetic basis of EOCRC gave rise to new alternative therapy protocols. Although exact diagnosis of these cases still remains complicated, the present review paves way for better predictions and contributes to more accurate diagnostic and therapeutic strategies into clinical approach. PMID:26798439

  15. Munchausen Syndrome by Proxy: Mother Fabricates Infant's Hearing Impairment.

    ERIC Educational Resources Information Center

    Kahn, Gerri; Goldman, Ellen

    1991-01-01

    Case study reports a case of Munchausen Syndrome by Proxy, a form of child abuse in which the mother presents a child for treatment for a condition she herself has invented or created. This case study describes the ways in which a mother obtained a diagnosis of sensorineural hearing loss as well as amplification for her normally hearing infant.…

  16. 26 CFR 1.6017-1 - Self-employment tax returns.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Revenue Service to such resident for use in lieu of Form 1040SS. (b) Joint returns. (1) In the case of a.... The requirement of section 6013(d)(3) that in the case of a joint return the tax is computed on the... tax in the case of a joint return is joint and several. (c) Social security account numbers. (1) Every...

  17. [Ultrasound semiotics in recurrent ovarian cancer after optimal cytoreductive surgery].

    PubMed

    Baklanova, N S; Kolomiets, L A; Frolova, I G; Viatkina, N V; Krasil'nikov, S É

    2014-01-01

    Features of ultrasound picture of morphologically verified recurrence of ovarian cancer in 21 patients are presented, who received combined treatment including cytoreductive surgery in the form of hysterectomy with oophorectomy, resection of the greater omentum and 6 courses of chemotherapy CAP for ovarian cancer stage III (FIGO). In all patients cytoreductive surgery was optimal--without residual tumor. Recurrence of the disease was detected in 12-48 months in 80.9% of the cases. Three variants of recurrence was revealed by ultrasonography: isolated peritoneal dissemination, in 14.2% of the cases, which was mainly detected during the first 12 months; single entities in the projection of the small pelvis (61.9%) and mixed form (local lesions of small pelvis and peritoneal dissemination) in 23.8% of the cases.

  18. Hepatoerythropoietic porphyria precipitated by viral hepatitis.

    PubMed Central

    Hift, R J; Meissner, P N; Todd, G

    1993-01-01

    Porphyria cutanea tarda (PCT), the condition resulting from a deficiency of hepatic uroporphyrinogen decarboxylase activity, is the commonest form of porphyria. Both acquired and familial form exist and are commonly associated in adults with liver disease and hepatic iron overload. The condition is extremely rare in children; most cases of childhood PCT are familial and some particularly severe cases have been shown to have a hepatoerythropoietic porphyria or homozygous uroporphyrinogen decarboxylase deficiency. A case is described of hepatoerythropoietic porphyria in which the disease was first precipitated at the age of two by a coincidental hepatitis A infection and improved as the hepatitis cleared. This paper reviews the evidence that viral hepatitis may precipitate overt PCT in children in a manner analogous to the precipitation of PCT in adults by alcohol associated liver disease. PMID:7902313

  19. Super periodic potential

    NASA Astrophysics Data System (ADS)

    Hasan, Mohammd; Mandal, Bhabani Prasad

    2018-04-01

    In this paper we introduce the concept of super periodic potential (SPP) of arbitrary order n, n ∈I+, in one dimension. General theory of wave propagation through SPP of order n is presented and the reflection and transmission coefficients are derived in their closed analytical form by transfer matrix formulation. We present scattering features of super periodic rectangular potential and super periodic delta potential as special cases of SPP. It is found that the symmetric self-similarity is the special case of super periodicity. Thus by identifying a symmetric fractal potential as special cases of SPP, one can obtain the tunnelling amplitude for a particle from such fractal potential. By using the formalism of SPP we obtain the close form expression of tunnelling amplitude of a particle for general Cantor and Smith-Volterra-Cantor potentials.

  20. Small-intestine pneumocystis jiroveci pseudotumor as an acquired immunodeficiency syndrome-presenting illness: report of a case and review of the literature.

    PubMed

    Zhou, Yi; Shetty, Jayarama; Pins, Michael R

    2012-09-01

    A Pneumocystis jiroveci infection-associated mass clinically mimicking a malignancy (ie, pseudotumor) is rare and usually occurs in the lung in association with Pneumocystis pneumonia. Pneumocystis jiroveci pseudotumors of the small intestine are extremely rare and represent an unusual form of disseminated P jiroveci infection. We present a case of small-intestine P jiroveci pseudotumor as an acquired immunodeficiency syndrome-presenting illness in a patient with coinfection with cytomegalovirus, no pulmonary symptoms, and no known risk factors for human immunodeficiency virus infection. This case reinforces the potential importance of cytomegalovirus coinfection in the disseminated form of Pneumocystis infection and illustrates the importance of an expanded differential diagnosis when confronted with a clinically atypical mass lesion.

  1. [APPLICATION OF COMPRESSION MINI-SCREWS IN TREATMENT OF PATIENTS WITH INJURY OF ELBOW JOINT BONES].

    PubMed

    Neverov, V A; Egorov, K S

    2015-01-01

    A case report presents the experience of application of compression pileateless mini-screws (Gerbert's screws) in treatment of intra-articular fractures, which formed the elbow joint (44 cases). There were performed 32 operations concerning fracture of head of radius, 10 operations on the occasion of fractures of distal section of the humerus and 2 operations on the coronoid process. Long-term treatment results were followed-up in 31 patients during more than 6 months. On basis of analysis of treatment results the authors made a conclusion that the application of mini-screws in case of bone fractures, which formed the elbow joint, allowed realization of stable osteosynthesis after anatomic reposition of articular surfaces, obtaining good anatomical and functional result and shortened the terms of patient's treatment.

  2. [Delayed diagnosis of neurocysticercosis: two case reports].

    PubMed

    Vandenbos, F; Boscagli-Melaine, A; Roth, S; Mondain-Miton, V; Paquis, P; Gari-Toussaint, M; Saint-Paul, M C; Montagne, N

    2002-04-01

    Neurocysticercosis is the most frequently encountered cerebral parasitic infection worldwide. It is due to infection of the central nervous system by Taenia solium larval form. According to the location of the cysts, parenchymal and extra-parenchymal forms may be identified, with different clinical expressions. We report two cases of neurocysticercosis, one with typical parenchymal involvement and the second with extra-parenchymal involvement revealed by increased intra-cranial pressure. In both cases, the diagnosis was established over 10 years after the onset of symptoms. Neurocysticercosis is very frequent in non-Islamic developing countries, and its incidence is increasing in industrialized nations in relation to tourism and immigration from highly endemic areas. Symptoms usually appear several years after infection and this accounts for the frequent delays before the diagnosis is established.

  3. Coexistence of brenner tumor and struma ovarii: case report.

    PubMed

    Takeuchi, K; Ohbayashi, C; Kitazawa, S; Ohara, N; Maruo, T

    2005-01-01

    There has been controversy regarding the histogenesis of Brenner tumors. It is generally accepted that Brenner tumors are derived directly from ovarian surface epithelium, which undergoes metaplasia to form the typical urothelial-like components, whereas some investigators assume that Brenner tumors arise from immature germ cells. We describe a well-documented case of the coexistence of struma ovarii regarded as a form of teratoma and Brenner tumor in the same ovary. Immunohistologically, not only columnar cells of thyroid follicles, but also transitional cells of Brenner nests were positive for thyroglobulin. In the present case, Brenner tumors and thyroid elements coexisted and were positive for thyroglobulin. While there is strong evidence that pure Brenner tumors originate mostly from the ovarian surface, at least Brenner tumors associated with teratomatous elements may have a germ cell origin.

  4. Travel history key to picking up on signs of bubonic plague.

    PubMed

    2015-11-01

    Health officials note an uptick in cases of bubonic plague in the United States this year, with at least 12 reported human cases reported since April 1. The CDC notes that healthcare providers should consider plague in patients who have traveled to plague-endemic areas and exhibit fever, headache, chills, weakness, and one or more swollen or tender and painful lymph nodes, referred to as buboes. Officials note that the disease rarely passes from person to person, but that this is a concern with patients who have developed the pneumonic form of the disease. Health officials note that in recent years there has been an average of seven cases of human plague each year in the United States, and that most of these cases are the bubonic form of the illness. Four patients confirmed to have plague this year have died, including the most recent case, a Utah man in his 70s. Most cases of plague in the United States occur in two regions. The first includes northern New Mexico, northern Arizona, and southern Colorado, and the second includes California, southern Oregon, and far western Nevada. When plague is suspected, treatment with antibiotics should begin immediately.

  5. Pneumonic tularaemia: experience of 58 cases from 2000 to 2012 in Northern Finland.

    PubMed

    Väyrynen, Sara A; Saarela, Elina; Henry, Janne; Lahti, Sini; Harju, Terttu; Kauma, Heikki

    2017-10-01

    Pneumonic tularaemia is less common clinical form of tularaemia compared with the ulceroglandular form, with only a limited number of case reports and case series in Europe. In Finland, Northern Ostrobothnia is an endemic area of tularaemia with occasional seasonal outbreaks. In our study, a consecutive series of 58 pneumonic tularaemia cases diagnosed and treated in Oulu University Hospital in 2000-2012 were retrospectively analysed in terms of epidemiology, clinical course, and prognosis. The incidence of pneumonic tularaemia showed peaks in cycles of a few years and most cases were diagnosed in late summer or early autumn. Respiratory symptoms were absent in 47% of patients, and 7% had normal chest X-ray. The chest computed tomography (CT) was performed in 81% of patients, demonstrating variable findings associated with pneumonic tularaemia. Bronchoscopy was performed for 22 (38%) patients and four (18%) of these also proceeded into mediastinoscopy. Moreover, thoracoscopy was performed for one (2%) patient. Two (3%) patients were treated shortly in the intensive care unit (ICU) during their stay in hospital. No mortality was observed. Most cases of pneumonic tularaemia are diagnosed during the seasonal outbreaks. The lack of specific symptoms often complicates the diagnosis and leads to unnecessarily invasive examinations.

  6. Comparative dermatology: elephantiasis nostra in verrucous form comparable to coral.

    PubMed

    Fernandes, Lana Bezerra; Fleury Junior, Luiz Fernando Fróes

    2011-01-01

    Study of a rare case of Elephantiasis Nostra in verrucous form on the dorsum of the foot of an 80 year-old male with a history of recurrent erysipelas infection. The vegetant, confluent lesions on the foot resemble Trumpet Coral (Caulastrea curvata).

  7. 7 CFR 1205.520 - Procedure for obtaining reimbursement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... application forms may be filed. In any such case, the reimbursement application shall show the names... Cotton Board shall make reimbursement to the importer. For joint applications, the reimbursement shall be... procedures prescribed in this section. (a) Application form. An importer shall obtain a reimbursement...

  8. 29 CFR 2520.104b-1 - Disclosure.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... documents furnished in electronic form at any location where the participant is reasonably expected to... or non-electronic form, to receiving documents through electronic media and has not withdrawn such consent; (B) In the case of documents to be furnished through the Internet or other electronic...

  9. 29 CFR 2520.104b-1 - Disclosure.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... documents furnished in electronic form at any location where the participant is reasonably expected to... or non-electronic form, to receiving documents through electronic media and has not withdrawn such consent; (B) In the case of documents to be furnished through the Internet or other electronic...

  10. 29 CFR 2520.104b-1 - Disclosure.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... documents furnished in electronic form at any location where the participant is reasonably expected to... or non-electronic form, to receiving documents through electronic media and has not withdrawn such consent; (B) In the case of documents to be furnished through the Internet or other electronic...

  11. 29 CFR 2520.104b-1 - Disclosure.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... documents furnished in electronic form at any location where the participant is reasonably expected to... or non-electronic form, to receiving documents through electronic media and has not withdrawn such consent; (B) In the case of documents to be furnished through the Internet or other electronic...

  12. STD Symptoms: Common STDs and Their Symptoms

    MedlinePlus

    ... groin. In some cases, the infection can be active and contagious even when sores aren't present. HPV infection is one of the most common types of STIs. Some forms put women at high risk of cervical cancer. Other forms cause genital warts. HPV usually has ...

  13. Canonical forms of multidimensional steady inviscid flows

    NASA Technical Reports Server (NTRS)

    Taasan, Shlomo

    1993-01-01

    Canonical forms and canonical variables for inviscid flow problems are derived. In these forms the components of the system governed by different types of operators (elliptic and hyperbolic) are separated. Both the incompressible and compressible cases are analyzed, and their similarities and differences are discussed. The canonical forms obtained are block upper triangular operator form in which the elliptic and non-elliptic parts reside in different blocks. The full nonlinear equations are treated without using any linearization process. This form enables a better analysis of the equations as well as better numerical treatment. These forms are the analog of the decomposition of the one dimensional Euler equations into characteristic directions and Riemann invariants.

  14. Thermal evolution of the metastable r8 and bc8 polymorphs of silicon

    DOE PAGES

    Haberl, Bianca; Guthrie, Malcolm; Sinogeikin, Stanislav V.; ...

    2015-01-28

    The kinetics of two metastable polymorphs of silicon under thermal annealing was investigated. These phases with body-centered cubic bc8 and rhombohedral r8 structures can be formed upon pressure release from metallic silicon.We study these metastable polymorphs were formed by two different methods, via point loading and in a diamond anvil cell (DAC). Upon thermal annealing different transition pathways were detected. In the point loading case, the previously reported Si-XIII formed and was confirmed as a new phase with an as-yet-unidentified structure. In the DAC case, bc8-Si transformed to the hexagonal-diamond structure at elevated pressure, consistent with previous studies at ambientmore » pressure. In contrast, r8-Si transformed directly to diamond-cubic Si at a temperature of 255⁰C. In conclusion, these data were used to construct diagrams of the metastability regimes of the polymorphs formed in a DAC and may prove useful for potential technological applications of these metastable polymorphs.« less

  15. Thermal evolution of the metastable r8 and bc8 polymorphs of silicon

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Haberl, Bianca; Guthrie, Malcolm; Sinogeikin, Stanislav V.

    The kinetics of two metastable polymorphs of silicon under thermal annealing was investigated. These phases with body-centered cubic bc8 and rhombohedral r8 structures can be formed upon pressure release from metallic silicon.We study these metastable polymorphs were formed by two different methods, via point loading and in a diamond anvil cell (DAC). Upon thermal annealing different transition pathways were detected. In the point loading case, the previously reported Si-XIII formed and was confirmed as a new phase with an as-yet-unidentified structure. In the DAC case, bc8-Si transformed to the hexagonal-diamond structure at elevated pressure, consistent with previous studies at ambientmore » pressure. In contrast, r8-Si transformed directly to diamond-cubic Si at a temperature of 255⁰C. In conclusion, these data were used to construct diagrams of the metastability regimes of the polymorphs formed in a DAC and may prove useful for potential technological applications of these metastable polymorphs.« less

  16. H theorem for generalized entropic forms within a master-equation framework

    NASA Astrophysics Data System (ADS)

    Casas, Gabriela A.; Nobre, Fernando D.; Curado, Evaldo M. F.

    2016-03-01

    The H theorem is proven for generalized entropic forms, in the case of a discrete set of states. The associated probability distributions evolve in time according to a master equation, for which the corresponding transition rates depend on these entropic forms. An important equation describing the time evolution of the transition rates and probabilities in such a way as to drive the system towards an equilibrium state is found. In the particular case of Boltzmann-Gibbs entropy, it is shown that this equation is satisfied in the microcanonical ensemble only for symmetric probability transition rates, characterizing a single path to the equilibrium state. This equation fulfils the proof of the H theorem for generalized entropic forms, associated with systems characterized by complex dynamics, e.g., presenting nonsymmetric probability transition rates and more than one path towards the same equilibrium state. Some examples considering generalized entropies of the literature are discussed, showing that they should be applicable to a wide range of natural phenomena, mainly those within the realm of complex systems.

  17. [Spontaneous hypoglycemia].

    PubMed

    Ellorhaoui, M; Schultze, W

    1977-01-15

    On the basis of a survey is attempted to describe mode of development, symptomatology, individual forms and the different possibilities of therapy of the spontaneous hypoglycaemias. A particularly broad range was devoted to the cerebral sequelae, since in these cases--according to our experience--on account of simulation of neurologico-psychiatric symptoms at the soonest wrong diagnoses are to be expected. Furthermore, it is attempted to classify the hypoglycemias according to their development, in which cases their incompleteness was evident from the very beginning. The individual forms of appearance are treated according their to significance. Out of the inducible hypoglycaemias a particular attention is devoted to the forms caused by insulin and oral antidiabetics, since these most frequently participate in the development. Finally the author inquires into diagnostic measures for recognition of special forms of hypoglycaemia. In this place the diagnostics of hyperinsulinism conditioned by adenomatosis or tumours of other kinds is of particular importance. Finally conservative and operative possibilities of the therapy of these tumours are discussed,whereby the only recently tested treatment with streptotocin is mentioned.

  18. Global alliances effect in coalition forming

    NASA Astrophysics Data System (ADS)

    Vinogradova, Galina; Galam, Serge

    2014-11-01

    Coalition forming is investigated among countries, which are coupled with short range interactions, under the influence of externally-set opposing global alliances. The model extends a recent Natural Model of coalition forming inspired from Statistical Physics, where instabilities are a consequence of decentralized maximization of the individual benefits of actors. In contrast to physics where spins can only evaluate the immediate cost/benefit of a flip of orientation, countries have a long horizon of rationality, which associates with the ability to envision a way up to a better configuration even at the cost of passing through intermediate loosing states. The stabilizing effect is produced through polarization by the global alliances of either a particular unique global interest factor or multiple simultaneous ones. This model provides a versatile theoretical tool for the analysis of real cases and design of novel strategies. Such analysis is provided for several real cases including the Eurozone. The results shed a new light on the understanding of the complex phenomena of planned stabilization in the coalition forming.

  19. Effect of forming gas annealing on the degradation properties of Ge-based MOS stacks

    NASA Astrophysics Data System (ADS)

    Aguirre, F.; Pazos, S.; Palumbo, F. R. M.; Fadida, S.; Winter, R.; Eizenberg, M.

    2018-04-01

    The influence of forming gas annealing on the degradation at a constant stress voltage of multi-layered germanium-based Metal-Oxide-Semiconductor capacitors (p-Ge/GeOx/Al2O3/High-K/Metal Gate) has been analyzed in terms of the C-V hysteresis and flat band voltage as a function of both negative and positive stress fields. Significant differences were found for the case of negative voltage stress between the annealed and non-annealed samples, independently of the stressing time. It was found that the hole trapping effect decreases in the case of the forming gas annealed samples, indicating strong passivation of defects with energies close to the valence band existing in the oxide-semiconductor interface during the forming gas annealing. Finally, a comparison between the degradation dynamics of Germanium and III-V (n-InGaAs) MOS stacks is presented to summarize the main challenges in the integration of reliable Ge-III-V hybrid devices.

  20. Naked singularity resolution in cylindrical collapse

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kurita, Yasunari; Yukawa Institute for Theoretical Physics, Kyoto University, Kyoto, 606-8502; Nakao, Ken-ichi

    In this paper, we study the gravitational collapse of null dust in cylindrically symmetric spacetime. The naked singularity necessarily forms at the symmetry axis. We consider the situation in which null dust is emitted again from the naked singularity formed by the collapsed null dust and investigate the backreaction by this emission for the naked singularity. We show a very peculiar but physically important case in which the same amount of null dust as that of the collapsed one is emitted from the naked singularity as soon as the ingoing null dust hits the symmetry axis and forms the nakedmore » singularity. In this case, although this naked singularity satisfies the strong curvature condition by Krolak (limiting focusing condition), geodesics which hit the singularity can be extended uniquely across the singularity. Therefore, we may say that the collapsing null dust passes through the singularity formed by itself and then leaves for infinity. Finally, the singularity completely disappears and the flat spacetime remains.« less

  1. The influence of averaging procedure on the accuracy of IVIVC predictions: immediate release dosage form case study.

    PubMed

    Ostrowski, Michalł; Wilkowska, Ewa; Baczek, Tomasz

    2010-12-01

    In vivo-in vitro correlation (IVIVC) is an effective tool to predict absorption behavior of active substances from pharmaceutical dosage forms. The model for immediate release dosage form containing amoxicillin was used in the presented study to check if the calculation method of absorption profiles can influence final results achieved. The comparison showed that an averaging of individual absorption profiles performed by Wagner-Nelson (WN) conversion method can lead to lose the discrimination properties of the model. The approach considering individual plasma concentration versus time profiles enabled to average absorption profiles prior WN conversion. In turn, that enabled to find differences between dispersible tablets and capsules. It was concluded that in the case of immediate release dosage form, the decision to use averaging method should be based on an individual situation; however, it seems that the influence of such a procedure on the discrimination properties of the model is then more significant. © 2010 Wiley-Liss, Inc. and the American Pharmacists Association

  2. Case Report: Laparoscopic Approach for Orchiopexy in a 26-Year-Old Man with Accidentally Discovered Persistent Müllerian Duct Syndrome and Bilateral Undescended Testis.

    PubMed

    Noureldin, Mohamed Essam; Tawfik, Ahmed Mohamed; Shaker, Hassan S

    2018-01-01

    Background: Persistent Müllerian duct syndrome (PMDS) is not a common form of disorder of sex development in which Müllerian duct derivatives (fallopian tubes, uterus, and the proximal vagina) are present in an otherwise normally differentiated 46 XY male. In most of cases, the challenge comes in the procedure of orchiopexy. Case Presentation: We report a case of a 26-year-old man with PMDS. It was accidentally discovered when the patient presented to our outpatient clinic concerning about his empty scrotum as a premarital check. Diagnostic laparoscopy discovered Mullerian remnants in the form of uterus, cervix, and fallopian tubes with two attached testes to the fallopian tubes. Staged laparoscopic orchiopexy was done. We discuss the presentation, the management of this case in the literature, and our intervention. Conclusion: PMDS is not a common condition. Several concerns present in the management of these cases. Malignant transformation of the testis is the main risk facing those patients. Few literature studies discussed the risk of changing of these remnants into malignant tissue. Thus discussion with the patient, tissue histopathology, expert opinions, and literature review are the main clues in management of such cases.

  3. Use of kangri (a traditional firepot) as a weapon.

    PubMed

    Rashid, Arsalaan F; Fazili, Rifat; Aggarwal, Akash D

    2014-08-01

    Kangri an earthenware firepot has been traditionally used by people of Kashmir for protecting themselves for harsh winter weather. This study done on patients admitted in the burns ward and general emergency ward of a tertiary care hospital, is perhaps the first of its kind. It analyses the use of this very traditional and useful art form as a weapon that can cause significant damage during interpersonal conflicts. As is clear from the study its use as weapon can inflict considerable damage and can lead to lifelong disabilities. Out of the 20 cases studied over a period of one year 2 cases received grievous injuries over head and face region in form of permanent disfigurement. Almost half of the injuries i.e. 7 cases were mechanical in nature whereas rest 13 cases belong to thermal category. Most of the injuries were simple and healed with preliminary medical attention but in 2 cases there was permanent disfigurement and both were because of deep burns. Copyright © 2014 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.

  4. [Ocular tuberculosis : A case series].

    PubMed

    Koubaa, M; Smaoui, F; Gargouri, S; Ben Ayed, H; Rekik, K; Abid, I; Maaloul, I; Feki, J; Marrakchi, C; Ben Jemaa, M

    2018-05-01

    Ocular tuberculosis is a rare form of extra pulmonary tuberculosis. It represents 1-2% of all clinical forms. The aim of this work was to focus on diagnostic and therapeutic characteristics of ocular tuberculosis. We report a case series of 14 patients with ocular tuberculosis seen in an infectious diseases department between 2006 and 2015. The diagnosis was retained on clinical data and a positive tuberculin skin test or interferon-gamma release assay. The patient's mean age was 40.7±9years. The most common clinical presentation was uveitis (11 patients and 16 eyes). An extra ocular involvement was associated in three patients. The mean duration of antitubercular therapy was 10±2.5 months. Corticosteroid therapy was associated in 11 cases. The outcome was favorable in all cases. Two patients had maintained visual sequelae. Ocular tuberculosis is a rare disease but still remains a diagnostic problem. It should be considered in case of any chronic ocular symptoms, especially in endemic countries. Early management can improve the visual prognosis. Copyright © 2018 Société Nationale Française de Médecine Interne (SNFMI). Published by Elsevier SAS. All rights reserved.

  5. Esophageal Perforation Following Anterior Cervical Spine Surgery: Case Report and Review of the Literature

    PubMed Central

    Hershman, Stuart H.; Kunkle, William A.; Kelly, Michael P.; Buchowski, Jacob M.; Ray, Wilson Z.; Bumpass, David B.; Gum, Jeffrey L.; Peters, Colleen M.; Singhatanadgige, Weerasak; Kim, Jin Young; Smith, Zachary A.; Hsu, Wellington K.; Nassr, Ahmad; Currier, Bradford L.; Rahman, Ra’Kerry K.; Isaacs, Robert E.; Smith, Justin S.; Shaffrey, Christopher; Thompson, Sara E.; Wang, Jeffrey C.; Lord, Elizabeth L.; Buser, Zorica; Arnold, Paul M.; Fehlings, Michael G.; Mroz, Thomas E.

    2017-01-01

    Study Design: Multicenter retrospective case series and review of the literature. Objective: To determine the rate of esophageal perforations following anterior cervical spine surgery. Methods: As part of an AOSpine series on rare complications, a retrospective cohort study was conducted among 21 high-volume surgical centers to identify esophageal perforations following anterior cervical spine surgery. Staff at each center abstracted data from patients’ charts and created case report forms for each event identified. Case report forms were then sent to the AOSpine North America Clinical Research Network Methodological Core for data processing and analysis. Results: The records of 9591 patients who underwent anterior cervical spine surgery were reviewed. Two (0.02%) were found to have esophageal perforations following anterior cervical spine surgery. Both cases were detected and treated in the acute postoperative period. One patient was successfully treated with primary repair and debridement. One patient underwent multiple debridement attempts and expired. Conclusions: Esophageal perforation following anterior cervical spine surgery is a relatively rare occurrence. Prompt recognition and treatment of these injuries is critical to minimizing morbidity and mortality. PMID:28451488

  6. Esophageal Perforation Following Anterior Cervical Spine Surgery: Case Report and Review of the Literature.

    PubMed

    Hershman, Stuart H; Kunkle, William A; Kelly, Michael P; Buchowski, Jacob M; Ray, Wilson Z; Bumpass, David B; Gum, Jeffrey L; Peters, Colleen M; Singhatanadgige, Weerasak; Kim, Jin Young; Smith, Zachary A; Hsu, Wellington K; Nassr, Ahmad; Currier, Bradford L; Rahman, Ra'Kerry K; Isaacs, Robert E; Smith, Justin S; Shaffrey, Christopher; Thompson, Sara E; Wang, Jeffrey C; Lord, Elizabeth L; Buser, Zorica; Arnold, Paul M; Fehlings, Michael G; Mroz, Thomas E; Riew, K Daniel

    2017-04-01

    Multicenter retrospective case series and review of the literature. To determine the rate of esophageal perforations following anterior cervical spine surgery. As part of an AOSpine series on rare complications, a retrospective cohort study was conducted among 21 high-volume surgical centers to identify esophageal perforations following anterior cervical spine surgery. Staff at each center abstracted data from patients' charts and created case report forms for each event identified. Case report forms were then sent to the AOSpine North America Clinical Research Network Methodological Core for data processing and analysis. The records of 9591 patients who underwent anterior cervical spine surgery were reviewed. Two (0.02%) were found to have esophageal perforations following anterior cervical spine surgery. Both cases were detected and treated in the acute postoperative period. One patient was successfully treated with primary repair and debridement. One patient underwent multiple debridement attempts and expired. Esophageal perforation following anterior cervical spine surgery is a relatively rare occurrence. Prompt recognition and treatment of these injuries is critical to minimizing morbidity and mortality.

  7. Linking case management and community development.

    PubMed

    Austin, Carol D; McClelland, Robert W; Gursansky, Di

    2006-01-01

    Case management, in various forms, is now institutionalized as a core part of policy and programs designed to deliver home- and community-based services to older adults. The case management role, in theory, requires attention to both client and system goals, although in practice the system goals that have received most attention have been gatekeeping and resource allocation. While case managers have been admonished to find and develop resources in the community, this has primarily taken the form of including informal services in individual client care plans. What has been missing is focused attention to the potential of the community as a nurturing environment with the capacity to support older adults and their caregivers. Sustainable care for older adults cannot be achieved by formal service and family support alone. This article proposes the creation of linkages between case managers, who build the service arrangements for older people, and community developers, who are responsible for building community capacity and social capital. It is argued that this linkage is essential for establishing the foundations of a caring community with the capacity to support older people.

  8. [Bone hydatidosis. 12 cases].

    PubMed

    Jlidi, R; Yaakoubi, M T; Ladeb, M F; Ben Ayeche, M L; Ghannouchi, G; Moula, T

    1992-01-01

    The hydatic cyst is a parasitic disease caused by the development in man of the larval form of echinococcus granulosus. All parts of the body may be involved, but the liver and lungs are the main locations of the disease. The bone site is rare, accounting for 0.9 to 2% of all hydatic lesions. Between 1982 and 1988, we have compiled 12 cases of hydatic disease of bone. They were located in the skull (4 cases), the iliac bone (4 cases), the omoplate (1 case), the ribs (1 case), the femur (1 case) and the fibula (1 case). These lesions are generally considered as primary, but association with visceral locations was noted in 3 cases in our series.

  9. Memorandum "Open Metadata". Open Access to Documentation Forms and Item Catalogs in Healthcare.

    PubMed

    Dugas, M; Jöckel, K-H; Friede, T; Gefeller, O; Kieser, M; Marschollek, M; Ammenwerth, E; Röhrig, R; Knaup-Gregori, P; Prokosch, H-U

    2015-01-01

    At present, most documentation forms and item catalogs in healthcare are not accessible to the public. This applies to assessment forms of routine patient care as well as case report forms (CRFs) of clinical and epidemiological studies. On behalf of the German chairs for Medical Informatics, Biometry and Epidemiology six recommendations to developers and users of documentation forms in healthcare were developed. Open access to medical documentation forms could substantially improve information systems in healthcare and medical research networks. Therefore these forms should be made available to the scientific community, their use should not be unduly restricted, they should be published in a sustainable way using international standards and sources of documentation forms should be referenced in scientific publications.

  10. 48 CFR 952.227-11 - Patent rights-retention by the contractor (short form).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... process or method; or to operate, in the case of a machine or system; and, in each case, under such... 60 days after learning of the failure of the Contractor to disclose or elect within the specified...

  11. 48 CFR 952.227-11 - Patent rights-retention by the contractor (short form).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... process or method; or to operate, in the case of a machine or system; and, in each case, under such... 60 days after learning of the failure of the Contractor to disclose or elect within the specified...

  12. 48 CFR 952.227-11 - Patent rights-retention by the contractor (short form).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... process or method; or to operate, in the case of a machine or system; and, in each case, under such... 60 days after learning of the failure of the Contractor to disclose or elect within the specified...

  13. 48 CFR 952.227-11 - Patent rights-retention by the contractor (short form).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... process or method; or to operate, in the case of a machine or system; and, in each case, under such... 60 days after learning of the failure of the Contractor to disclose or elect within the specified...

  14. The protein folds as platonic forms: new support for the pre-Darwinian conception of evolution by natural law.

    PubMed

    Denton, Michael J; Marshall, Craig J; Legge, Michael

    2002-12-07

    Before the Darwinian revolution many biologists considered organic forms to be determined by natural law like atoms or crystals and therefore necessary, intrinsic and immutable features of the world order, which will occur throughout the cosmos wherever there is life. The search for the natural determinants of organic form-the celebrated "Laws of Form"-was seen as one of the major tasks of biology. After Darwin, this Platonic conception of form was abandoned and natural selection, not natural law, was increasingly seen to be the main, if not the exclusive, determinant of organic form. However, in the case of one class of very important organic forms-the basic protein folds-advances in protein chemistry since the early 1970s have revealed that they represent a finite set of natural forms, determined by a number of generative constructional rules, like those which govern the formation of atoms or crystals, in which functional adaptations are clearly secondary modifications of primary "givens of physics." The folds are evidently determined by natural law, not natural selection, and are "lawful forms" in the Platonic and pre-Darwinian sense of the word, which are bound to occur everywhere in the universe where the same 20 amino acids are used for their construction. We argue that this is a major discovery which has many important implications regarding the origin of proteins, the origin of life and the fundamental nature of organic form. We speculate that it is unlikely that the folds will prove to be the only case in nature where a set of complex organic forms is determined by natural law, and suggest that natural law may have played a far greater role in the origin and evolution of life than is currently assumed.

  15. Couplings of gravitational currents with Chern-Simons gravities

    NASA Astrophysics Data System (ADS)

    Ertem, Ümit; Açık, Özgür

    2013-02-01

    The coupling of conserved p-brane currents with non-Abelian gauge theories is done consistently by using Chern-Simons forms. Conserved currents localized on p-branes that have a gravitational origin can be constructed from Killing-Yano forms of the underlying spacetime. We propose a generalization of the coupling procedure with Chern-Simons gravities to the case of gravitational conserved currents. In odd dimensions, the field equations of coupled Chern-Simons gravities that describe the local curvature on p-branes are obtained. In special cases of three and five dimensions, the field equations are investigated in detail.

  16. Psychogenic and organic amnesia: a multidimensional assessment of clinical, neuroradiological, neuropsychological and psychopathological features.

    PubMed

    Serra, Laura; Fadda, Lucia; Buccione, Ivana; Caltagirone, Carlo; Carlesimo, Giovanni A

    2007-01-01

    Psychogenic amnesia is a complex disorder characterised by a wide variety of symptoms. Consequently, in a number of cases it is difficult distinguish it from organic memory impairment. The present study reports a new case of global psychogenic amnesia compared with two patients with amnesia underlain by organic brain damage. Our aim was to identify features useful for distinguishing between psychogenic and organic forms of memory impairment. The findings show the usefulness of a multidimensional evaluation of clinical, neuroradiological, neuropsychological and psychopathological aspects, to provide convergent findings useful for differentiating the two forms of memory disorder.

  17. Cryotherapy as a conservative treatment modality for gingival enlargement in a patient with Sturge-Weber Syndrome

    PubMed Central

    Yadav, Vikender Singh; Chakraborty, Souvik; Tewari, Shikha; Tewari, Nitesh; Ghosh, Tuhina

    2017-01-01

    Summary This case report describes a case of Sturge-Weber syndrome reported for unilateral gingival enlargement and bleeding from gingiva in maxillary left region. Initial treatment in the form of scaling and root planing was done but recurrence was observed after one year of follow up. Instead of performing conventional surgery, an alternative conservative treatment was planned in the form of cryotherapy with the help of closed nitrous oxide probe. Seeing the satisfactory results obtained, cryotherapy can be suggested as an atraumatic, bloodless and effective chair side procedure for treating vascular gingival enlargement. PMID:28580218

  18. Comment on ‘Special-case closed form of the Baker-Campbell-Hausdorff formula’

    NASA Astrophysics Data System (ADS)

    Lo, C. F.

    2016-05-01

    Recently Van-Brunt and Visser (2015 J. Phys. A: Math. Theor. 48 225207) succeeded in explicitly evaluating the Baker-Campbell-Hausdorff (BCH) expansion series for the noncommuting operators X and Y, provided that the two operators satisfy the commutation relation: [X,Y]={uX}+{vY}+{cI}, and the operator I commutes with both of them. In this comment we show that the closed-form BCH formula of this special case can be straightforwardly derived by the means of the Wei-Norman theorem and no summation of the infinite series is needed.

  19. The statistical theory of the fracture of fragile bodies. Part 2: The integral equation method

    NASA Technical Reports Server (NTRS)

    Kittl, P.

    1984-01-01

    It is demonstrated how with the aid of a bending test, the Weibull fracture risk function can be determined - without postulating its analytical form - by resolving an integral equation. The respective solutions for rectangular and circular section beams are given. In the first case the function is expressed as an algorithm and in the second, in the form of series. Taking into account that the cumulative fracture probability appearing in the solution to the integral equation must be continuous and monotonically increasing, any case of fabrication or selection of samples can be treated.

  20. High Bone Mass is associated with bone-forming features of osteoarthritis in non-weight bearing joints independent of body mass index.

    PubMed

    Gregson, C L; Hardcastle, S A; Murphy, A; Faber, B; Fraser, W D; Williams, M; Davey Smith, G; Tobias, J H

    2017-04-01

    High Bone Mass (HBM) is associated with (a) radiographic knee osteoarthritis (OA), partly mediated by increased BMI, and (b) pelvic enthesophytes and hip osteophytes, suggestive of a bone-forming phenotype. We aimed to establish whether HBM is associated with radiographic features of OA in non-weight-bearing (hand) joints, and whether such OA demonstrates a bone-forming phenotype. HBM cases (BMD Z-scores≥+3.2) were compared with family controls. A blinded assessor graded all PA hand radiographs for: osteophytes (0-3), joint space narrowing (JSN) (0-3), subchondral sclerosis (0-1), at the index Distal Interphalangeal Joint (DIPJ) and 1st Carpometacarpal Joint (CMCJ), using an established atlas. Analyses used a random effects logistic regression model, adjusting a priori for age and gender. Mediating roles of BMI and bone turnover markers (BTMs) were explored by further adjustment. 314 HBM cases (mean age 61.1years, 74% female) and 183 controls (54.3years, 46% female) were included. Osteophytes (grade≥1) were more common in HBM (DIPJ: 67% vs. 45%, CMCJ: 69% vs. 50%), with adjusted OR [95% CI] 1.82 [1.11, 2.97], p=0.017 and 1.89 [1.19, 3.01], p=0.007 respectively; no differences were seen in JSN. Further adjustment for BMI failed to attenuate ORs for osteophytes in HBM cases vs. controls; DIPJ 1.72 [1.05, 2.83], p=0.032, CMCJ 1.76 [1.00, 3.06], p=0.049. Adjustment for BTMs (concentrations lower amongst HBM cases) did not attenuate ORs. HBM is positively associated with OA in non-weight-bearing joints, independent of BMI. HBM-associated OA is characterised by osteophytes, consistent with a bone-forming phenotype, rather than JSN reflecting cartilage loss. Systemic factors (e.g. genetic architecture) which govern HBM may also increase bone-forming OA risk. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  1. Chilblains in Southern California: two case reports and a review of the literature.

    PubMed

    Gordon, Rebecca; Arikian, Anne M; Pakula, Anita S

    2014-11-22

    Chilblains or perniosis is an acrally located cutaneous eruption that occurs with exposure to cold. Chilblains can be classified into primary and secondary forms. The primary or idiopathic form is not associated with an underlying disease and is clinically indistinguishable from the secondary form. The secondary form is associated with an underlying condition such as connective tissue disease, monoclonal gammopathy, cryoglobulinemia, or chronic myelomonocytic leukemia. Histopathology cannot accurately help distinguish the primary from secondary forms of chilblains. This article will raise the awareness of chilblains by presenting two unusual case reports of chilblains in men from Southern California with discussion of the appropriate evaluation and treatment of this condition. Case 1: A 56-year-old Caucasian man presented in January to a Southern California primary care clinic with a report of tingling and burning in both feet, followed by bluish discoloration and swelling as well as blistering. He had no unusual cold exposure prior to the onset of his symptoms. He had a history of "white attacks" in his hands consistent with Raynaud's phenomenon. His symptoms gradually resolved over a 3-week period. Case 2: A 53-year-old Caucasian man also presented to a Southern California clinic in January with a 3-week history of painful tingling in his toes, and subsequent purplish-black discoloration of the toes in both feet. His symptoms occurred 1 week after a skiing trip. He had partial improvement with warming measures. His symptoms resolved 2 weeks after his initial presentation. Chilblains is a relatively uncommon entity in warmer climates but can present during the winter months. Primary care providers in warmer climates such as Southern California in the USA may be unfamiliar with its presentation. It can be diagnosed clinically by the appearance of typical lesions during the cold damp season. Through a thorough history, physical examination and selected laboratory evaluation, underlying connective tissue disease or a mimic such as vasculitis or cutaneous leukemia can be excluded.

  2. Corneal ulcer due to a rare coelomycetes fungus Chaetomium strumarium: Case report and global review of Chaetomium keratomycosis

    PubMed Central

    Reddy, Mamatha; Venugopal, Ramya; Prakash, Peralam Yegneswaran; Kamath, Yogish Subraya

    2017-01-01

    We present a rare case of corneal ulcer caused by a species of a coelomycetes fungus, Chaetomium strumarium. This fungal genus is a rare causative agent of keratomycosis, with only a handful of cases reported. The clinical presentation, investigative techniques, and preliminary management of our patient are reported. The cases reported in global literature are also summarized in a tabular form in the discussion. PMID:28905835

  3. Dermatophyte infections mimicking other skin diseases: a 154-person case survey of tinea atypica in the district of Cagliari (Italy).

    PubMed

    Atzori, Laura; Pau, Monica; Aste, Natalia; Aste, Nicola

    2012-04-01

    Although usually simple, the diagnosis of dermatophyte infection is sometimes neglected. An observational study has been realized to evaluate the role of corticosteroid exposure (tinea incognito) and of other primary characteristics of the dermatophytosis that from onset mimic other diseases and mislead an unexperienced physician. Between 1990 and 2009, all cases of atypical dermatophytosis mimicking other skin diseases were collected from the more general number of dermatophyte infections diagnosed at the Dermatology Department of Cagliari University, Italy. One-hundred and fifty-four cases (71 male/83 female, 2-81 years old) were studied, with a median of 7 cases/year. The most observed clinical forms were those mimicking impetigo, eczematous dermatitis, lupus erythematosus, polymorphous light eruption, psoriasis, and rosacea. The identified dermatophytes were: Microsporum canis (70 cases), Trichophyton rubrum (43 cases), Trichophyton mentagrophytes var. mentagrophytes (29 cases), Trichophyton mentagrophytes var. interdigitale (six cases), Microsporum gypseum (three cases), Epidermophyton floccosum (two cases), and Trichophyton verrucosum (one case). Diagnostic difficulties are discussed, with special attention to the origin of the pathomorphosis. In our experience, clinical atypia is not a mere consequence of corticosteroid therapy but present at the very onset of the illness, due to the variable dermatophyte invasive capacity, the site of invasion, physiological individual, and/or acquired condition, such as excessive washing or sun exposure. Therefore, we suggest using the term "tinea atypica" rather than "tinea incognito" to include all forms of dermatophytosis that do not present the classic features for both primary and secondary pathomorphosis. © 2012 The International Society of Dermatology.

  4. Ten years' experience of Directly Observed Treatment Short-course (DOTS) in Gambella Regional State, Ethiopia: An evaluation of tuberculosis control program.

    PubMed

    Sisay, Solomon; Mengistu, Belete; Erku, Woldargay; Woldeyohannes, Desalegne

    2016-12-01

    World Health Organization (WHO) declared tuberculosis (TB) as a global public health emergency and recommended DOTS as a standard strategy for controlling the disease. TB is one of the major causes of infectious diseases in the world, and 25% of all avoidable deaths in developing countries. About a third of the world's population is estimated to be infected with tubercle bacilli, and hence at risk of developing active disease. The objective of the study was, therefore, to evaluate the impact of DOTS strategy on smear-positive pulmonary tuberculosis case finding and their treatment outcomes in Gambella Regional State, Ethiopia. A retrospective health facility-based descriptive study was employed. Quarterly data were collected by using WHO structured reporting format for TB case finding and treatment outcome from all DOTS implementing health facilities in the region. A total of 10,024 TB cases (all forms) were registered and reported between the periods from 2003 up to 2012. Out of these, 4100 (40.9%) were smear-positive pulmonary TB, 3164 (31.6%) were smear-negative pulmonary TB and 2760 (27.5%) had extra-pulmonary TB. An average case detection rate (CDR) 1 of 40.9% (SD=0.1) and treatment success rate (TSR) 2 of 55.7% (SD=0.28) for smear-positive pulmonary TB including other forms of TB were reported for the specified years period. Additionally, the average mean values of treatment defaulter and treatment failure rates were 4.2% and 0.3%, respectively. The recommended TSR set by WHO was achieved as it was already been fulfilled more than 85% from 2009 up to 2011 in the region and the reported CDR was far below (40.9%) for smear-positive pulmonary TB including other forms of TB from the target. Therefore, extensive efforts should be established to maintain the achieved TSR and to increase the low level of CDR for all forms of TB cases through implementing alternative case finding strategies. Copyright © 2016.

  5. Standardizing data exchange for clinical research protocols and case report forms: An assessment of the suitability of the Clinical Data Interchange Standards Consortium (CDISC) Operational Data Model (ODM).

    PubMed

    Huser, Vojtech; Sastry, Chandan; Breymaier, Matthew; Idriss, Asma; Cimino, James J

    2015-10-01

    Efficient communication of a clinical study protocol and case report forms during all stages of a human clinical study is important for many stakeholders. An electronic and structured study representation format that can be used throughout the whole study life-span can improve such communication and potentially lower total study costs. The most relevant standard for representing clinical study data, applicable to unregulated as well as regulated studies, is the Operational Data Model (ODM) in development since 1999 by the Clinical Data Interchange Standards Consortium (CDISC). ODM's initial objective was exchange of case report forms data but it is increasingly utilized in other contexts. An ODM extension called Study Design Model, introduced in 2011, provides additional protocol representation elements. Using a case study approach, we evaluated ODM's ability to capture all necessary protocol elements during a complete clinical study lifecycle in the Intramural Research Program of the National Institutes of Health. ODM offers the advantage of a single format for institutions that deal with hundreds or thousands of concurrent clinical studies and maintain a data warehouse for these studies. For each study stage, we present a list of gaps in the ODM standard and identify necessary vendor or institutional extensions that can compensate for such gaps. The current version of ODM (1.3.2) has only partial support for study protocol and study registration data mainly because it is outside the original development goal. ODM provides comprehensive support for representation of case report forms (in both the design stage and with patient level data). Inclusion of requirements of observational, non-regulated or investigator-initiated studies (outside Food and Drug Administration (FDA) regulation) can further improve future revisions of the standard. Published by Elsevier Inc.

  6. Prader-Willi syndrome: intellectual abilities and behavioural features by genetic subtype.

    PubMed

    Milner, Katja M; Craig, Ellen E; Thompson, Russell J; Veltman, Marijcke W M; Thomas, N Simon; Roberts, Sian; Bellamy, Margaret; Curran, Sarah R; Sporikou, Caroline M J; Bolton, Patrick F

    2005-10-01

    Studies of chromosome 15 abnormality have implicated over-expression of paternally imprinted genes in the 15q11-13 region in the aetiology of autism. To test this hypothesis we compared individuals with Prader-Willi syndrome (PWS) due to uniparental disomy (UPD--where paternally imprinted genes are over-expressed) to individuals with the 15q11-13 deletion form of the syndrome (where paternally imprinted genes are not over-expressed). We also tested reports that PWS cases due to the larger type I (TI) form of deletion show differences to cases with the smaller type II (TII) deletion. Ninety-six individuals with PWS were recruited from genetic centres and the PWS association. Forty-nine individuals were confirmed as having maternal UPD of chromosome 15 and were age and sex matched to 47 individuals with a deletion involving 15q11-13 (32 had the shorter (T II) deletion, and 14 had the longer (TI) deletion). Behavioural assessments were carried out blind to genetic status, using the Autism Diagnostic Observation Schedule (ADOS), the Autism Diagnostic Interview (ADI), the Autism Screening Questionnaire (ASQ), the Children's Yale-Brown Obsessive-Compulsive Scale (CY-BOCS), the Vineland Adaptive Behaviour Scales (VABS), and measurements of intellectual ability, including the Wechsler and Mullen Scales and Raven's Matrices. UPD cases exhibited significantly more autistic-like impairments in reciprocal social interaction on questionnaire, interview and standardised observational measures. Comparison of TI and TII deletion cases revealed few differences, but ability levels tended to be lower in the TI deletion cases. Findings from a large study comparing deletion and UPD forms of Prader-Willi syndrome were consistent with other evidence in indicating that paternally imprinted genes in the 15q11-13 region constitute a genetic risk factor for aspects of autistic symptomatology. These genes may therefore play a role in the aetiology of autism. By contrast with another report, there was no clear-cut relationship between the size of the deletion and the form of cognitive and behavioural phenotype.

  7. 78 FR 40151 - Agency Forms Undergoing Paperwork Reduction Act Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-03

    .... 0920-0852, All Age Influenza Hospitalization Surveillance); however this request seeks to have these... 10 60/60 Influenza Hospitalization 10 400 15/60 Surveillance Project Case Report Form. Influenza Hospitalization 10 100 5/60 Surveillance Project Vaccination Telephone Survey. Influenza Hospitalization 10 100 5...

  8. 16 CFR 1130.6 - Requirements for format of registration forms.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... manufacturer's name and mailing address where registration information is to be collected. (c) Font size and typeface. The registration form shall use bold black typeface. The size of the type shall be at least 12... information shall be in capital and lower case type. ...

  9. Cryptococcus neoformans of Unusual Morphology

    PubMed Central

    Cruickshank, J. G.; Cavill, R.; Jelbert, M.

    1973-01-01

    A case of primary cryptococcosis of the lungs was caused by an isolate of Cryptococcus neoformans that assumes a giant form in tissue but which has a normal appearance on artificial culture. Electron microscopy revealed gross enlargement of the capsule and plasma membranes in the tissue form. Images PMID:4121033

  10. Pseudo-Equivalent Groups and Linking

    ERIC Educational Resources Information Center

    Haberman, Shelby J.

    2015-01-01

    Adjustment by minimum discriminant information provides an approach to linking test forms in the case of a nonequivalent groups design with no satisfactory common items. This approach employs background information on individual examinees in each administration so that weighted samples of examinees form pseudo-equivalent groups in the sense that…

  11. Method of producing an integral resonator sensor and case

    NASA Technical Reports Server (NTRS)

    Challoner, A. Dorian (Inventor); Yee, Karl Y. (Inventor); Shcheglov, Kirill V. (Inventor); Hayworth, Ken J. (Inventor); Wiberg, Dean V. (Inventor)

    2005-01-01

    The present invention discloses an inertial sensor having an integral resonator. A typical sensor comprises a planar mechanical resonator for sensing motion of the inertial sensor and a case for housing the resonator. The resonator and a wall of the case are defined through an etching process. A typical method of producing the resonator includes etching a baseplate, bonding a wafer to the etched baseplate, through etching the wafer to form a planar mechanical resonator and the wall of the case and bonding an end cap wafer to the wall to complete the case.

  12. [Case and studies].

    PubMed

    Schubert, András

    2015-11-15

    Case studies and case reports form an important and ever growing part of scientific and scholarly literature. The paper deals with the share and citation rate of these publication types on different fields of research. In general, evidence seems to support the opinion that an excessive number of such publications may negatively influence the impact factor of the journal. In the literature of scientometrics, case studies (at least the presence of the term "case study" in the titles of the papers) have a moderate share, but their citation rate is practically equal to that of other publication types.

  13. The virtual-casing principle and Helmholtz's theorem

    DOE PAGES

    Hanson, J. D.

    2015-09-10

    The virtual-casing principle is used in plasma physics to convert a Biot–Savart integration over a current distribution into a surface integral over a surface that encloses the current. In many circumstances, use of virtual casing can significantly speed up the computation of magnetic fields. In this paper, a virtual-casing principle is derived for a general vector field with arbitrary divergence and curl. This form of the virtual-casing principle is thus applicable to both magnetostatic fields and electrostatic fields. The result is then related to Helmholtz's theorem.

  14. The virtual-casing principle and Helmholtz’s theorem

    DOE PAGES

    Hanson, J. D.

    2015-09-10

    The virtual-casing principle is used in plasma physics to convert a Biot–Savart integration over a current distribution into a surface integral over a surface that encloses the current. In many circumstances, use of virtual casing can significantly speed up the computation of magnetic fields. In this paper, a virtual-casing principle is derived for a general vector field with arbitrary divergence and curl. This form of the virtual-casing principle is thus applicable to both magnetostatic fields and electrostatic fields. The result is then related to Helmholtz’s theorem.

  15. Regularity Results for a Class of Functionals with Non-Standard Growth

    NASA Astrophysics Data System (ADS)

    Acerbi, Emilio; Mingione, Giuseppe

    We consider the integral functional under non-standard growth assumptions that we call p(x) type: namely, we assume that a relevant model case being the functional Under sharp assumptions on the continuous function p(x)>1 we prove regularity of minimizers. Energies exhibiting this growth appear in several models from mathematical physics.

  16. Multiple forms of rhythmic movements in an adolescent boy with rhythmic movement disorder.

    PubMed

    Su, Changjun; Miao, Jianting; Liu, Yu; Liu, Rui; Lei, Gesheng; Zhang, Wei; Yang, Ting; Li, Zhuyi

    2009-12-01

    Rhythmic movement disorder (RMD) refers to a group of stereotyped, repetitive movements involving large muscles, usually occurring prior to the onset of sleep and persisting into sleep. RMD more commonly exhibits only one or two forms of rhythmic movements (RM) in most reported cases. However, multiple RM forms of RMD occurring in a patient in the same night have rarely been reported. In this report, we present the unique case of a 15-year-old boy with RMD affected by multiple forms of RM in the same night, including four known forms (i.e., body rocking, head banging, leg rolling, and rhythmic feet movements) and two new kinds of RM (bilateral rhythmic arm rocking and rhythmic hands movements). Two video-polysomnographic recordings were performed in this patient before starting pharmacologic treatment and after long-term oral clonazepam treatment (1.0mg nightly for 3 months). The characteristics of RMD with multiple RM forms and the effectiveness of clonazepam on the RM episodes and polysomnographic findings observed in our patient are discussed. This report raises the fact that a patient with RMD may present with multiple complex rhythmic movements disrupting sleep, which emphasizes that better understanding of the clinical features of complex rhythmic movements during sleep in primary care settings is essential for early clinical diagnosis and optimal management.

  17. Chronic thrombotic obstruction of major pulmonary arteries : report of a case successfully treated by thrombendarterectomy, and a review of the literature.

    DOT National Transportation Integrated Search

    1963-08-01

    A case is reported of chronic massive thromboembolic occlusion of major pulmonary arterial branches successfully treated with embolectomy and endarterectomy. The historic features, physical signs and pathophysiologic alterations which form the basis ...

  18. Neurofibromatosis, pathological fracture and hypervitaminosis-D.

    PubMed

    Mondal, Rakesh; Nandi, Madhumita; Chandra, P K

    2010-10-01

    Pathologic fractures in children may be due to various causes. Rarely, it may be the presenting symptom of neurofibromatosis. A misdiagnosis of Rickets and Vitamin D supplementation in such a case may wreak havoc in the form of iatrogenic hypervitaminosis D. We report one such case.

  19. Foreign bodies retained in the vagina: a case report.

    PubMed

    Nanda, Smiti; Singhal, Savita Rani; Marya, Ashima

    2006-04-01

    Foreign bodies have been found in the vagina in a variety of forms. A 3-year-old girl had a variety of foreign bodies in her vagina. One should always think of foreign bodies in the vagina in cases of vaginal discharge in childhood.

  20. Cultural Identity and Regional Security in the Western Balkans

    DTIC Science & Technology

    2013-06-13

    possible. Case Study as Qualitative Approach Creswell and other experts of the social research methodology suggest at least five forms of...descriptive research approach, and the main method is case study of the Western Balkans. This thesis utilizes the analytical frameworks of securitization

  1. Knowledge Co-production at the Research-Practice Interface: Embedded Case Studies from Urban Forestry.

    PubMed

    Campbell, Lindsay K; Svendsen, Erika S; Roman, Lara A

    2016-06-01

    Cities are increasingly engaging in sustainability efforts and investment in green infrastructure, including large-scale urban tree planting campaigns. In this context, researchers and practitioners are working jointly to develop applicable knowledge for planning and managing the urban forest. This paper presents three case studies of knowledge co-production in the field of urban forestry in the United States. These cases were selected to span a range of geographic scales and topical scopes; all three are examples of urban researcher-practitioner networks in which the authors are situated to comment on reflexively. The three cases resemble institutional structures described in the knowledge co-production literature, including participatory research, a hybrid organization of scientists and managers, and a community of practice. We find that trust, embeddedness, new approaches by both practitioners and researchers, and blending of roles all serve to recognize multiple forms of capability, expertise, and ways of knowing. We discuss the impacts of knowledge co-production and the ways in which hybrid institutional forms can enable its occurrence.

  2. [Atypical cerebellar neurocytoma resembling a hemangioblastoma. A case report].

    PubMed

    Lista Martínez, Olalla; Rivas López, Luis Alfredo; Pombo Otero, Jorge Francisco; Amaro Cendón, Santiago; Bravo García, Christian; Villa Fernández, Juan Manuel

    2014-01-01

    Through August 2013, 105 cases of intracranial extraventricular neurocytoma (EVN) had been described; 6% were located in cerebellum and 22% were atypical EVN. A rare morphologic form of neurocytoma, atypical EVN has had only 24 cases reported to date. Its prognosis is poorer than the typical central neurocytoma. This case report describes an atypical cerebellar EVN, a form that has not been reported yet, hence the interest of this article. We emphasise its cystic nature and mural nodule, in an infrequent presentation. EVN are low-incidence tumours that we need to take into consideration when making the differential diagnosis of cystic cerebellar lesions with mural nodule. Given that the prognosis of atypical EVNs depends on the atypical nature and on the grade of resection, medical follow up has to be more constant, due to the greater degree of recurrence. Copyright © 2013 Sociedad Española de Neurocirugía. Published by Elsevier España. All rights reserved.

  3. A Gel Formulation Containing a New Recombinant Form of Manganese Superoxide Dismutase: A Clinical Experience Based on Compassionate Use-Safety of a Case Report

    PubMed Central

    Prete, Antonio Del; Ortosecco, Giovanni; Borrelli, Antonella; Prete, Salvatore Del; Mancini, Aldo

    2016-01-01

    Background. We report a case of bilateral posterior subcapsular cataracts (PSCs) in a 24-year-old man with an allergic conjunctivitis history caused by a long-term therapy with glucocorticoids. Case Presentation. The patient showed a visual acuity of 9/10 for both eyes. He followed a therapy with ketotifen and bilastine for four years. During the last six months before our evaluation, he was treated with chloramphenicol and betamethasone, interrupted for onset of cataracts and increased intraocular pressure. We treated him with ophthalmic gel preparation containing a new recombinant form of manganese superoxide dismutase (rMnSOD) at a concentration of 12.5 μg/mL, only for the right eye, while left eye was treated with standard protocol of Bendazac-lysine g 0.5. Conclusion. This case report shows the protective effects of rMnSOD versus PSC disease, probably due to the capacity of rMnSOD of countering free radical species. PMID:27610257

  4. Scombroid poisoning. Case series of 10 incidents involving 22 patients.

    PubMed

    Müller, G J; Lamprecht, J H; Barnes, J M; De Villiers, R V; Honeth, B R; Hoffman, B A

    1992-04-18

    Scombroid poisoning is a form of ichthyosarcotoxism caused by the consumption of 'spoiled' fish of the dark meat varieties. It can be considered a mild-to-moderate form of 'food poisoning' and it occurs world-wide. Ten incidents, involving 22 patients, were reported to Tygerberg Hospital Pharmacology and Toxicology Consultation Centre in the first quarter of 1990. Cape yellowtail (Seriola lalandii) was involved in all the cases. The presenting symptoms and signs (in order of frequency) were: skin rash, diarrhoea, palpitations, headache, nausea and abdominal cramps, paraesthesia, an unusual taste sensation and breathing difficulties. The patients responded well to anti-histamines and, in most, the condition resolved within 12-24 hours. Although histamine plays an important role in the pathogenesis of scombroid poisoning, the exact mechanism is still unresolved. The condition should be recognised and not confused with a true seafood allergy. Health workers are urged to alert the authorities when outbreaks of suspected cases of scombroid poisoning are encountered in order to establish the possible cause and to prevent further cases.

  5. A Gel Formulation Containing a New Recombinant Form of Manganese Superoxide Dismutase: A Clinical Experience Based on Compassionate Use-Safety of a Case Report.

    PubMed

    Grumetto, Lucia; Prete, Antonio Del; Ortosecco, Giovanni; Borrelli, Antonella; Prete, Salvatore Del; Mancini, Aldo

    2016-01-01

    Background. We report a case of bilateral posterior subcapsular cataracts (PSCs) in a 24-year-old man with an allergic conjunctivitis history caused by a long-term therapy with glucocorticoids. Case Presentation. The patient showed a visual acuity of 9/10 for both eyes. He followed a therapy with ketotifen and bilastine for four years. During the last six months before our evaluation, he was treated with chloramphenicol and betamethasone, interrupted for onset of cataracts and increased intraocular pressure. We treated him with ophthalmic gel preparation containing a new recombinant form of manganese superoxide dismutase (rMnSOD) at a concentration of 12.5 μg/mL, only for the right eye, while left eye was treated with standard protocol of Bendazac-lysine g 0.5. Conclusion. This case report shows the protective effects of rMnSOD versus PSC disease, probably due to the capacity of rMnSOD of countering free radical species.

  6. Relationship between Human Papilloma Virus and Subungual Keratoacanthoma: Two Case Reports and the Outcomes of Surgical Treatment.

    PubMed

    Göktay, Fatih; Kaynak, Emre; Güneş, Pembegül; Yaşar, Şirin; Küçükodacı, Zafer; Aytekin, Sema

    2017-01-01

    Subungual keratoacanthoma (SUKA) is a rare form of keratoacanthoma, with the majority of the lesions appearing as rapidly growing, painful hyperkeratotic masses located under the distal nail plate of the thumb. In some cases, SUKA causes damage to the underlying bone. The first case presented here was treated by surgical excision alone, and human papilloma virus (HPV) type 6 was detected in the tissue samples. The second case was treated by surgical excision plus curettage; however, HPV was not detected, and tumor cells were not found in the curettage material. There was near complete improvement in both the clinical appearance and the distal phalanx destruction, with no recurrence at the final follow-up in either patient (30 and 14 months, respectively). Overall, simple excision alone or in combination with curettage seemed to be sufficient in the treatment of SUKA; however, the etiopathogenetic role of HPV in SUKA remains controversial, as in its classical form.

  7. Knowledge Co-production at the Research-Practice Interface: Embedded Case Studies from Urban Forestry

    NASA Astrophysics Data System (ADS)

    Campbell, Lindsay K.; Svendsen, Erika S.; Roman, Lara A.

    2016-06-01

    Cities are increasingly engaging in sustainability efforts and investment in green infrastructure, including large-scale urban tree planting campaigns. In this context, researchers and practitioners are working jointly to develop applicable knowledge for planning and managing the urban forest. This paper presents three case studies of knowledge co-production in the field of urban forestry in the United States. These cases were selected to span a range of geographic scales and topical scopes; all three are examples of urban researcher-practitioner networks in which the authors are situated to comment on reflexively. The three cases resemble institutional structures described in the knowledge co-production literature, including participatory research, a hybrid organization of scientists and managers, and a community of practice. We find that trust, embeddedness, new approaches by both practitioners and researchers, and blending of roles all serve to recognize multiple forms of capability, expertise, and ways of knowing. We discuss the impacts of knowledge co-production and the ways in which hybrid institutional forms can enable its occurrence.

  8. Characterizing dense suspensions: two case studies from the pharmaceutical industry

    NASA Astrophysics Data System (ADS)

    Goldfarb, David J.; Khawaja, Nazia; Kazakevich, Irina; Bhattacharjee, Himanshu; Heslinga, Michael; Dalton, Chad

    2015-11-01

    Liquid suspensions of Active Pharmaceutical Ingredient powders are present as pharmaceutical dosage forms in the form of oral suspensions and injectables. We present two case studies, both dense (~ 30-40%) suspensions, in which the physical characterization of the product, specifically, particle size & shape and rheology were key to understanding the key product attributes as pertaining to the manufacturing process and to patient administration. For the one case study, an oral suspension, identifying variations in particle morphology during the wet milling of the product was key to the product understanding necessary to modify the milling process. Rheological measurements were applied as well. For the second case study, an injectable, results from different particle size measurement techniques and rheological measurements indicated the possibility of flocculation in a formulation. Additionally, measurements were obtained to assess the ``injectability'' of the product via rheometer and texture analyzer measurements and Poiseuille flow modeling. As a result, the relevant shear rate regime for this drug product administration was identified.

  9. [Neurological complications of infectious mononucleosis (author's transl)].

    PubMed

    Rousseau, J J; Franck, G

    1977-01-01

    The authors report three different and rare forms of neurological complication associated with infectious mononucleosis. The first two, which are faily unusual in their clinical signs, occurred during the course of two typical cases of mononucleosis, one in the form of progressively regressive myelitis and the other in that of amyotrophic paralysis of the shoulder. The third occurred in isolation, after an encephalitic attack combined with a state of epileptic mal, with no other accompanying infectious sign. On the basis of these three single cases, and recent data in the literature about the Epstein-Barr virus, the authors briefly recapitulate the neurological clinical forms of infectious monouncleosis and the means of serological diagnosis; they discuss the frequency and pathogeny of these complications and tentatively suggest certain similarities with other nervous disorders observed in the course of proliferative or dysglobulinaemic diseases.

  10. A linear biopolymer in the vicinity of the triple point. The homopolymer case.

    PubMed

    Frank-Kamenetskii, M D; Chogovadze, G I

    1984-06-01

    This is a theoretical study of a situation where each residue of a linear biopolymer may adopt one of three conformational states. Such a situation exists in the case of DNA, since it may be in helical A, B, . . ., Z forms as well as the melted state. In the vicinity of the triple point in the phrase diagram three states, e.g. the A form, the B form and the denatured state, co-exist within a given molecule. We present an exact analytical solution of the simplest homopolymer model. Theory predicts that the presence of two helical states in one molecule should affect the helix-coil transition in two ways. The melting temperature experiences an upward shift and the melting range width is increased, by a factor of square root of two as a maximum.

  11. Completeness of tuberculosis reporting forms in five Brazilian capitals with a high incidence of the disease.

    PubMed

    Santos, Normeide Pedreira dos; Lírio, Monique; Passos, Louran Andrade Reis; Dias, Juarez Pereira; Kritski, Afrânio Lineu; Galvão-Castro, Bernardo; Grassi, Maria Fernanda Rios

    2013-01-01

    The aim of this study was to evaluate the completeness of tuberculosis reporting forms in the greater metropolitan areas of five Brazilian capitals where the incidence of tuberculosis was high in 2010 - Salvador, Rio de Janeiro, Cuiabá, Porto Alegre, and Belém - using tabulations obtained from the Sistema Nacional de Informação de Agravos de Notificação (National Case Registry Database). The degree of completeness was highest in Porto Alegre and Cuiabá, whereas it was lowest in Rio de Janeiro, where there are more reported cases of tuberculosis than in any other Brazilian capital. A low degree of completeness of these forms can affect the quality of the Brazilian National Tuberculosis Control Program, which will have negative consequences for health care and decision-making processes.

  12. Thin oblique airfoils at supersonic speed

    NASA Technical Reports Server (NTRS)

    Jone, Robert T

    1946-01-01

    The well-known methods of thin-airfoil theory have been extended to oblique or sweptback airfoils of finite aspect ratio moving at supersonic speeds. The cases considered thus far are symmetrical airfoils at zero lift having plan forms bounded by straight lines. Because of the conical form of the elementary flow fields, the results are comparable in simplicity to the results of the two-dimensional thin-airfoil theory for subsonic speeds. In the case of untapered airfoils swept back behind the Mach cone the pressure distribution at the center section is similar to that given by the Ackeret theory for a straight airfoil. With increasing distance from the center section the distribution approaches the form given by the subsonic-flow theory. The pressure drag is concentrated chiefly at the center section and for long wings a slight negative drag may appear on outboard sections. (author)

  13. Functional form for plasma velocity in a rapidly rotating tokamak discharge

    DOE PAGES

    Burrell, Keith H.; Chrystal, C. olin

    2014-07-25

    A recently developed technique using charge exchange spectroscopy determines the ion poloidal rotation in tokamak plasmas from the poloidal variation in the toroidal angular rotation speed. The basis for this technique is the functional form for the plasma velocity calculated from the equilibrium equations. The initial development of this technique utilized the functional form determined for conditions where the ion toroidal rotation speed is much smaller than the ion thermal speed. There are cases, however, where the toroidal rotation can be comparable to the ion thermal speed, especially for high atomic number impurities. Furthermore, the present paper extends the previousmore » analysis to this high rotation speed case and demonstrates how to extract the poloidal rotation speed from measurements of the toroidal angular rotation speed at two points on a flux surface.« less

  14. Morphometric investigations on the portal tracts of the liver, the differentiation of variable progression in chronic persistent hepatitis.

    PubMed

    Volmer, J; Lüders, C J

    1981-01-01

    Morphometric investigations were carried out on the portal tracts of the liver in different forms of chronic hepatitis. The investigation groups each contained 25 liver biopsies, which were subdivided into cases with normal liver, a subsiding acute virus hepatitis, three different forms of chronic persistent hepatitis (CPH) and chronic aggressive hepatitis type IIa (CAH IIa). Determinations of the volume and surface of the portal tracts and their components enabled three forms of COH (type Ia, Ib, Ic) to be characterised. Preliminary clinical and semiquantitative histological investigations were correlated with a significant difference in the histological characteristics and prognosis. HBsAg-positive and HBsAg-negative cases showed no significant morphologically detectable differences in all grups investigated. Morphometry is suitable for investigation of pathological changes in liver tissue, especially the portal tracts.

  15. Completeness of tuberculosis reporting forms in five Brazilian capitals with a high incidence of the disease *

    PubMed Central

    dos Santos, Normeide Pedreira; Lírio, Monique; Passos, Louran Andrade Reis; Dias, Juarez Pereira; Kritski, Afrânio Lineu; Galvão-Castro, Bernardo; Grassi, Maria Fernanda Rios

    2013-01-01

    The aim of this study was to evaluate the completeness of tuberculosis reporting forms in the greater metropolitan areas of five Brazilian capitals where the incidence of tuberculosis was high in 2010-Salvador, Rio de Janeiro, Cuiabá, Porto Alegre, and Belém-using tabulations obtained from the Sistema Nacional de Informação de Agravos de Notificação (National Case Registry Database). The degree of completeness was highest in Porto Alegre and Cuiabá, whereas it was lowest in Rio de Janeiro, where there are more reported cases of tuberculosis than in any other Brazilian capital. A low degree of completeness of these forms can affect the quality of the Brazilian National Tuberculosis Control Program, which will have negative consequences for health care and decision-making processes. PMID:23670508

  16. Rules vs. Statistics: Insights from a Highly Inflected Language

    PubMed Central

    Mirković, Jelena; Seidenberg, Mark S.; Joanisse, Marc F.

    2011-01-01

    Inflectional morphology has been taken as a paradigmatic example of rule-governed grammatical knowledge (Pinker, 1999). The plausibility of this claim may be related to the fact that it is mainly based on studies of English, which has a very simple inflectional system. We examined the representation of inflectional morphology in Serbian, which encodes number, gender and case for nouns. Linguists standardly characterize this system as a complex set of rules, with disagreements about their exact form. We present analyses of a large corpus of nouns which showed that, as in English, Serbian inflectional morphology is quasiregular: it exhibits numerous partial regularities creating neighborhoods that vary in size and consistency. We then asked whether a simple connectionist network could encode this statistical information in a manner that also supported generalization. A network trained on 3,244 Serbian nouns learned to produce correctly inflected phonological forms from a specification of a word’s lemma, gender, number and case, and generalized to untrained cases. The model’s performance was sensitive to variables that also influence human performance, including surface and lemma frequency. It was also influenced by inflectional neighborhood size, a novel measure of the consistency of meaning to form mapping. A word naming experiment with native Serbian speakers showed that this measure also affects human performance. The results suggest that, as in English, generating correctly inflected forms involves satisfying a small number of simultaneous probabilistic constraints relating form and meaning. Thus, common computational mechanisms may govern the representation and use of inflectional information across typologically diverse languages. PMID:21564267

  17. Impact of inhomogeneity on SH-type wave propagation in an initially stressed composite structure

    NASA Astrophysics Data System (ADS)

    Saha, S.; Chattopadhyay, A.; Singh, A. K.

    2018-02-01

    The present analysis has been made on the influence of distinct form of inhomogeneity in a composite structure comprised of double superficial layers lying over a half-space, on the phase velocity of SH-type wave propagating through it. Propagation of SH-type wave in the said structure has been examined in four distinct cases of inhomogeneity viz. when inhomogeneity in double superficial layer is due to exponential variation in density only (Case I); when inhomogeneity in double superficial layers is due to exponential variation in rigidity only (Case II); when inhomogeneity in double superficial layer is due to exponential variation in rigidity, density and initial stress (Case III) and when inhomogeneity in double superficial layer is due to linear variation in rigidity, density and initial stress (Case IV). Closed-form expression of dispersion relation has been accomplished for all four aforementioned cases through extensive application of Debye asymptotic analysis. Deduced dispersion relations for all the cases are found in well-agreement to the classical Love-wave equation. Numerical computation has been carried out to graphically demonstrate the effect of inhomogeneity parameters, initial stress parameters as well as width ratio associated with double superficial layers in the composite structure for each of the four aforesaid cases on dispersion curve. Meticulous examination of distinct cases of inhomogeneity and initial stress in context of considered problem has been carried out with detailed analysis in a comparative approach.

  18. The Case Study: I'm Looking over a White-Striped Clover--A Case of Natural Selection

    ERIC Educational Resources Information Center

    Krufka, Alison; Evarts, Susan; Wilson, Chester

    2007-01-01

    The case presented in this article is an exploration of the process of natural selection using white clover ("Trifolium repens") as an example. In general, two forms of white clover can be found around the world in various habitats. One type has plain green leaves and the other type produces cyanide as a defense against herbivores and…

  19. Cyclosporine in the Treatment of a Case of Fulminant and Refractory Acute Disseminated Encephalomyelitis

    PubMed Central

    Taghdiri, Mohammd-Mehdi; Amanati, Ali; Abdolkarimi, Babak

    2011-01-01

    Background Acute disseminated encephalomyelitis (ADEM) is a rare, monophasic, demyelinating disease of the CNS which sometimes could be refractory to traditional treatment. Case Presentation We present a case of fulminant ADEM which is treated with combination of corticosteroid, intravenous immunoglobulin and cyclosporine. Conclusion Immunosuppressive agents such as cyclosporine may be effective especially in fulminant form of the disease. PMID:23056845

  20. Small Data, Online Learning and Assessment Practices in Higher Education: A Case Study of Failure?

    ERIC Educational Resources Information Center

    Watson, Cate; Wilson, Anna; Drew, Valerie; Thompson, Terrie Lynn

    2017-01-01

    In this paper, we present an in-depth case study of a single student who failed an online module which formed part of a master's programme in Professional Education and Leadership. We use this case study to examine assessment practices in higher education in the online environment. In taking this approach, we go against the current predilection…

  1. Intellectual Property Rights and International Trade

    DTIC Science & Technology

    2009-02-05

    case . The WTO panel ruled in the United States’ favor that China’s denial of copyright protection to works that do not have censorship approval is...In the case of patents, infringement of a patent owner’s exclusive rights (as afforded by patent laws) involves a third party’s unauthorized...3 Counterfeit goods should be distinguished from generic goods, i.e., in the case of generic forms of pharmaceutical

  2. Experimental study of void formation during aluminum solidification in reduced gravity. Ph.D. Thesis - Toledo Univ.

    NASA Technical Reports Server (NTRS)

    Chiaramonte, Francis Paul, III

    1993-01-01

    Void formation due to volumetric shrinkage and liquid/vapor reorientation during aluminum solidification was observed in real time by using a radiographic viewing system in normal and reduced gravity. An end-chill directional solidification furnace with water quench was designed and constructed to solidify aluminum samples during the approximately 16 sec of reduced gravity (+/-0.02g) achieved by flying an aircraft through a parabolic trajectory. In the first series of tests the aluminum was contained in a vacuum sealed, pyrolytic boron nitride crucible. An ullage space was present during each test. Void formation was recorded for two cases: a nonwetting system, and a wetting system where wetting occurred between the aluminum and the crucible lid. The void formation in the nonwetting case was similar in normal and reduced gravity, with a single vapor cavity forming at the top of the crucible. In the wetting case during reduced gravity surface tension caused two voids to form in the top corners of the crucible, but during normal gravity only one large void formed across the top. In the second series of tests the aluminum was contained in a pyrolytic boron nitride crucible that was placed in a stainless steel container and sealed in an environment of argon plus 4 percent hydrogen. An ullage space was present during each test. Void formation was recorded for two cases: a nonwetting system, and a wetting system where wetting occurred between the aluminum and one side wall and the lid. The void for nation in the nonwetting case was similar in normal and reduced gravity, with a single vapor cavity forming at the top of the crucible, although the meniscus became more convex in reduced gravity. In the wetting case the aluminum did not climb up the corners in 1g, and one large symmetric void resulted at the top when the aluminum had solidified. In the wetting case during reduced gravity the molten aluminum was drawn up the wetted wall and partially across the lid by a capillary underpressure; however, on the nonwetting wall the aluminum moved down. One void resulted along the nonwetting side of the container continuing to the top on the same side.

  3. Visual form-processing deficits: a global clinical classification.

    PubMed

    Unzueta-Arce, J; García-García, R; Ladera-Fernández, V; Perea-Bartolomé, M V; Mora-Simón, S; Cacho-Gutiérrez, J

    2014-10-01

    Patients who have difficulties recognising visual form stimuli are usually labelled as having visual agnosia. However, recent studies let us identify different clinical manifestations corresponding to discrete diagnostic entities which reflect a variety of deficits along the continuum of cortical visual processing. We reviewed different clinical cases published in medical literature as well as proposals for classifying deficits in order to provide a global perspective of the subject. Here, we present the main findings on the neuroanatomical basis of visual form processing and discuss the criteria for evaluating processing which may be abnormal. We also include an inclusive diagram of visual form processing deficits which represents the different clinical cases described in the literature. Lastly, we propose a boosted decision tree to serve as a guide in the process of diagnosing such cases. Although the medical community largely agrees on which cortical areas and neuronal circuits are involved in visual processing, future studies making use of new functional neuroimaging techniques will provide more in-depth information. A well-structured and exhaustive assessment of the different stages of visual processing, designed with a global view of the deficit in mind, will give a better idea of the prognosis and serve as a basis for planning personalised psychostimulation and rehabilitation strategies. Copyright © 2011 Sociedad Española de Neurología. Published by Elsevier Espana. All rights reserved.

  4. The development of proliferative verrucous leukoplakia in oral lichen planus. A preliminary study

    PubMed Central

    Llorente-Pendás, Santiago; González-Garcia, Manuel; García-Martín, José-Manuel

    2016-01-01

    Background Was to describe 14 cases of a proliferative verrucous leukoplakia as a clinical evolution of oral lichen planus. Material and Methods The clinical and histopathological characteristics of 14 cases of OLP that progress towards a plaque-like and verrucous form were indicated, with monitoring over a period of six to 24.3 years. Results The female/male ratio was 11/3, (78.6 and 21.4%). The mean age when the first biopsy was undertaken was 56.4 years old. None of the patients smoked during the study. As bilateral reticular was clinically diagnostic criterion, the second most frequent clinical form was the plaque form (n=10; 71.4%), followed by the atrophic (n=6; 42.8%), and erosive forms (n=4; 28.5%). Clinically it spread towards attached gingival mucosa and the hard palate. In the histopathologic study, there were a predominance of hyperkeratosis and verrucous epithelial hyperplasia. Three of the cases progressed to a squamous cell carcinoma, and one patient developed two verrucous carcinoma. Conclusions Further research is needed to demonstrate if proliferative multifocal oral lichen planus and proliferative multifocal oral leukoplakia are the same disorder but have different behaviour of malignancy for reasons of origin. Key words:Oral lichen planus, proliferative verrucous oral leukoplakia, malignant oral lichen planus, multifocal verrucous oral lichen planus, proliferative verrucous oral lichen planus. PMID:27031060

  5. [Frequency of opportunistic infections in children with immune neutropenia and their mothers].

    PubMed

    Kalugina, M Iu; Karazhas, N V; Rybalkina, T N; Bosh'ian, R E; Mamedova, E A; Polovtseva, T V; Finogenova, N A

    2012-01-01

    Determine the frequency of opportunistic infections among children with immune neutropenia and their mothers. 66 mothers and 66 children with immune neutropenia diagnosis were examined for the presence of herpes (HV) and pneumocystic infection. Opportunistic infections markers (IgM, IgG, early and late antigens, virus reproduction) were determined by enzyme immunoassay, immunofluorescence reaction and rapid culture method (vero, u937, human fibroblasts). Pneumocystosis was the most active infection in the group. Among mothers 26 (39.3%) cases of pneumocystic infection in acute form were detected, among children - 18 (27.3%) cases. Infection occurred only in acute form during primary infection; there were no cases of its reactivation, which is an indication of recent pneumocystosis infection. Analysis of data on detection of acute and recent herpes infections showed that HV infection markers were determined in a relatively large number of mothers and their children: herpes simplex virus - 21.2%, Epstein-Barr virus - 12.0%, cytomegalovirus - 15.0%, Human herpesvirus 6 - 10.6%, Pneumocystis carinii - 21.2%. The data provided give evidence on a possible family pattern of the infection. A necessity of examination of mothers and their children suffering from immune neutropenia was shown because the specified opportunistic infections can form intra-family foci. The presence of acute form of infection in mother may be one of the conditions of development of this infection in the child.

  6. The role of semantics, pre-emption and skew in linguistic distributions: the case of the un-construction

    PubMed Central

    Ibbotson, Paul

    2013-01-01

    We use the Google Ngram database, a corpus of 5,195,769 digitized books containing ~4% of all books ever published, to test three ideas that are hypothesized to account for linguistic generalizations: verbal semantics, pre-emption and skew. Using 828,813 tokens of un-forms as a test case for these mechanisms, we found verbal semantics was a good predictor of the frequency of un-forms in the English language over the past 200 years—both in terms of how the frequency changed over time and their frequency rank. We did not find strong evidence for the direct competition of un-forms and their top pre-emptors, however the skew of the un-construction competitors was inversely correlated with the acceptability of the un-form. We suggest a cognitive explanation for this, namely, that the more the set of relevant pre-emptors is skewed then the more easily it is retrieved from memory. This suggests that it is not just the frequency of pre-emptive forms that must be taken into account when trying to explain usage patterns but their skew as well. PMID:24399991

  7. Phonologically Driven Variability: The Case of Determiners

    ERIC Educational Resources Information Center

    Bürki, Audrey; Laganaro, Marina; Alario, F.-Xavier

    2014-01-01

    Speakers usually produce words in connected speech. In such contexts, the form in which many words are uttered is influenced by the phonological properties of neighboring words. The current article examines the representations and processes underlying the production of phonologically constrained word form variations. For this purpose, we consider…

  8. Defamation of and by Principals. A Legal Memorandum.

    ERIC Educational Resources Information Center

    Zirkel, Perry A.

    Defamation is a common-law claim for liability that encompasses "libel," which is the written form, and "slander," which is the oral form. School principals can be plaintiffs or defendants in defamation suits. Relevant case law provides illustrations of the various elements of defamation for both roles of the principal. Court…

  9. 78 FR 15368 - Agency Forms Undergoing Paperwork Reduction Act Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-11

    ..., Legionellosis, Lyme disease, Malaria, Plague, Q Fever, Reye Syndrome, Tickborne Rickettsial Disease, Trichinosis, Tularemia, Typhoid Fever, and Viral Hepatitis. Case report forms from state and territorial health... Epidemiologist Trichinosis 25 1 20/60 Epidemiologist Tularemia 55 2 20/60 Epidemiologist Typhoid Fever 55 6 20/60...

  10. Superconductivity as a Synchronous Spatial Alternation of Valence Bonds.

    DTIC Science & Technology

    1987-04-01

    approach. 9 This is likely to be the case in three-dimensions as well. As pair breaking excitations ( magnons ) can be formed at essentially no energy...cost (remember the form of the magnon dispersion curve of 1-D Heisenberg model), superconductivity cannot be achieved. In principle, these metals can be

  11. Evaluation of the fatigue and toughness of fiber reinforced concrete for use as a new highway pavement design.

    DOT National Transportation Integrated Search

    2016-04-01

    Concrete pavement design is currently centered on steel reinforcement, whether that reinforcement be in the : form of dowel bars, as is the case in jointed plain concrete pavement (JPCP), or in the form of continuous rebar : reinforcement, continuous...

  12. Market Segmentation in Higher Education: A Case Study.

    ERIC Educational Resources Information Center

    Muffo, John A.

    1987-01-01

    A survey of applicants accepted by a major research university found that among the most sought-after applicants, academic scholarships and other forms of forms of financial aid were more likely to have influenced college choice, putting the institution with minimal non-need-based financial aid at a competitive disadvantage. (MSE)

  13. 27 CFR 478.144 - Relief from disabilities under the Act.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... discharged from the Armed Forces under dishonorable conditions, a copy of the applicant's summary of service record (Department of Defense Form 214), charge sheet (Department of Defense Form 458), and final court... the conviction was rendered nugatory or that civil rights were restored; (5) In the case of an...

  14. 27 CFR 478.144 - Relief from disabilities under the Act.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... discharged from the Armed Forces under dishonorable conditions, a copy of the applicant's summary of service record (Department of Defense Form 214), charge sheet (Department of Defense Form 458), and final court... the conviction was rendered nugatory or that civil rights were restored; (5) In the case of an...

  15. Forms of Mediation: The Case of Interpreter-Mediated Interactions in Medical Systems

    ERIC Educational Resources Information Center

    Baraldi, Claudio

    2009-01-01

    This paper analyses the forms of mediation in interlinguistic interactions performed in Italian healthcare services and in contexts of migration. The literature encourages dialogic transformative mediation, empowering participants' voices and changing cultural presuppositions in social systems. It may be doubtful, however, whether mediation can…

  16. 32 CFR Appendix A to Part 651 - References

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... publications and forms are accessible from a variety of sources through the use of electronic media or paper products. In most cases, electronic publications and forms that are associated with military organizations can be accessed at various address or web sites on the Internet. Since electronic addresses can...

  17. 32 CFR Appendix A to Part 651 - References

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... publications and forms are accessible from a variety of sources through the use of electronic media or paper products. In most cases, electronic publications and forms that are associated with military organizations can be accessed at various address or web sites on the Internet. Since electronic addresses can...

  18. 32 CFR Appendix A to Part 651 - References

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... publications and forms are accessible from a variety of sources through the use of electronic media or paper products. In most cases, electronic publications and forms that are associated with military organizations can be accessed at various address or web sites on the Internet. Since electronic addresses can...

  19. Transient Structured Distance as a Maneuver in Marital Therapy

    ERIC Educational Resources Information Center

    Greene, Bernard L.; And Others

    1973-01-01

    Experience with 73 cases has shown the value of Transient Structured Distance as a maneuver in marriage therapy. While the TSD is a radical form of intervention with risks of anxiety reactions, homosexual panic, or divorce, it has proved effective with difficult forms of acute or chronic marital disharmony. (Author)

  20. Emergency Planning and Community Right-to-Know Act Section 312 Tier Two report forms

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Evans, R.A.

    2000-02-01

    The report contains forms for the chemical description, physical and health hazards, inventory volumes, and storage codes and locations for all hazardous chemicals located at the Y-12 Plant. These can be used by local emergency response teams in case of an accident.

  1. 78 FR 38341 - Federal Acquisition Regulation; Information Collection; Preaward Survey Forms (Standard Forms...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-26

    ... Contractor Accounting System Respondents: 708. Responses annually: 1. Total Responses: 708. Hours per... contractor responsibility in each case. B. Annual Reporting Burden There are no Governmentwide systems for... Procurement Data System (FPDS) ad hoc report was completed identifying that in Fiscal Year (FY) 2012 an...

  2. Emergency Planning and Community Right-To-Know Act Section 312 Tier Two report forms

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Evans, R.A.

    2000-02-01

    The report contains forms for the chemical description, physical and health hazards, inventory volumes, and storage codes and locations for all hazardous chemicals located at the Y-12 Plant. These can be used by local emergency response teams in case of an accident.

  3. Collaborative Approach in Software Engineering Education: An Interdisciplinary Case

    ERIC Educational Resources Information Center

    Vicente, Aileen Joan; Tan, Tiffany Adelaine; Yu, Alvin Ray

    2018-01-01

    Aim/Purpose: This study was aimed at enhancing students' learning of software engineering methods. A collaboration between the Computer Science, Business Management, and Product Design programs was formed to work on actual projects with real clients. This interdisciplinary form of collaboration simulates the realities of a diverse Software…

  4. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hanson, J. D.

    The virtual-casing principle is used in plasma physics to convert a Biot–Savart integration over a current distribution into a surface integral over a surface that encloses the current. In many circumstances, use of virtual casing can significantly speed up the computation of magnetic fields. In this paper, a virtual-casing principle is derived for a general vector field with arbitrary divergence and curl. This form of the virtual-casing principle is thus applicable to both magnetostatic fields and electrostatic fields. The result is then related to Helmholtz's theorem.

  5. Gestational diabetes insipidus: a morphological study of the placenta.

    PubMed

    Castiglione, F; Buccoliero, A M; Garbini, F; Gheri, C F; Moncini, D; Poggi, G; Saladino, V; Rossi Degl'Innocenti, D; Gheri, R G; Taddei, G L

    2009-12-01

    Gestational diabetes insipidus (GDI) refers to the state of excessive water intake and hypotonic polyuria. Those cases manifesting in pregnancy and referred to as GDI may persist thereafter or may be a transient latent form that resolves after delivery. Microscopic examination of affected subjects has not been previously reported. In the literature, there are various case reports and case series on diabetes insipidus in pregnancy. In this study, we present a case that had transient diabetes insipidus during pregnancy in which the placenta was examined.

  6. The impact of the form of the Euler equations for radial flow in cylindrical and spherical coordinates on numerical conservation and accuracy

    NASA Astrophysics Data System (ADS)

    Crittenden, P. E.; Balachandar, S.

    2018-07-01

    The radial one-dimensional Euler equations are often rewritten in what is known as the geometric source form. The differential operator is identical to the Cartesian case, but source terms result. Since the theory and numerical methods for the Cartesian case are well-developed, they are often applied without modification to cylindrical and spherical geometries. However, numerical conservation is lost. In this article, AUSM^+-up is applied to a numerically conservative (discrete) form of the Euler equations labeled the geometric form, a nearly conservative variation termed the geometric flux form, and the geometric source form. The resulting numerical methods are compared analytically and numerically through three types of test problems: subsonic, smooth, steady-state solutions, Sedov's similarity solution for point or line-source explosions, and shock tube problems. Numerical conservation is analyzed for all three forms in both spherical and cylindrical coordinates. All three forms result in constant enthalpy for steady flows. The spatial truncation errors have essentially the same order of convergence, but the rate constants are superior for the geometric and geometric flux forms for the steady-state solutions. Only the geometric form produces the correct shock location for Sedov's solution, and a direct connection between the errors in the shock locations and energy conservation is found. The shock tube problems are evaluated with respect to feature location using an approximation with a very fine discretization as the benchmark. Extensions to second order appropriate for cylindrical and spherical coordinates are also presented and analyzed numerically. Conclusions are drawn, and recommendations are made. A derivation of the steady-state solution is given in the Appendix.

  7. The different molecular forms of urine neutrophil gelatinase-associated lipocalin present in dogs with urinary diseases.

    PubMed

    Hsu, Wei-Li; Chiou, Hsiao-Chi; Tung, Kwong-Chung; Belot, Guillaume; Virilli, Anais; Wong, Min-Liang; Lin, Fong-Yuan; Lee, Ya-Jane

    2014-08-27

    Neutrophil gelatinase-associated lipocalin (NGAL) is a useful biomarker for the early prediction of renal diseases. NGAL may exist as monomer, dimer and/or NGAL/MMP-9 complex forms in humans. In this study, the existence of various forms of NGAL in urine (uNGAL) was determined and whether these forms are related to the different urinary diseases found in dogs is further discussed. Eighty-one urine samples from dogs with different forms of renal disease (41), pyuria (19) and a number of non-renal related diseases (10), as well as healthy dogs (11), were collected. uNGAL concentrations and their molecular forms in dogs were measured by ELISA and Western blot analysis, respectively. The uNGAL concentrations of dogs with pyuria (median: 15.35 ng/mL) were significantly higher than those of the healthy control animals (median: 3.92 ng/mL) (p < 0.01), but lower than those of dogs with renal diseases (median: 23.77 ng/mL). Each NGAL molecular form could be detected in dog urine. In particular, monomer was detected more frequently in patients with renal disease than those with non-renal diseases; while the dimer form appeared in a significantly higher percentage of cases with pyuria compared to those without pyuria. The NGAL/MMP-9 complex was found to exist not only in the patients with cystitis, but also in the cases with renal injury. Different molecular forms of uNGAL can indicate different origins of the urinary abnormalities. Determining the molecular forms of uNGAL present in diseased dogs may provide clinical workers with a tool that will help the early and more precise detection of different urinary diseases.

  8. The impact of the form of the Euler equations for radial flow in cylindrical and spherical coordinates on numerical conservation and accuracy

    NASA Astrophysics Data System (ADS)

    Crittenden, P. E.; Balachandar, S.

    2018-03-01

    The radial one-dimensional Euler equations are often rewritten in what is known as the geometric source form. The differential operator is identical to the Cartesian case, but source terms result. Since the theory and numerical methods for the Cartesian case are well-developed, they are often applied without modification to cylindrical and spherical geometries. However, numerical conservation is lost. In this article, AUSM^+ -up is applied to a numerically conservative (discrete) form of the Euler equations labeled the geometric form, a nearly conservative variation termed the geometric flux form, and the geometric source form. The resulting numerical methods are compared analytically and numerically through three types of test problems: subsonic, smooth, steady-state solutions, Sedov's similarity solution for point or line-source explosions, and shock tube problems. Numerical conservation is analyzed for all three forms in both spherical and cylindrical coordinates. All three forms result in constant enthalpy for steady flows. The spatial truncation errors have essentially the same order of convergence, but the rate constants are superior for the geometric and geometric flux forms for the steady-state solutions. Only the geometric form produces the correct shock location for Sedov's solution, and a direct connection between the errors in the shock locations and energy conservation is found. The shock tube problems are evaluated with respect to feature location using an approximation with a very fine discretization as the benchmark. Extensions to second order appropriate for cylindrical and spherical coordinates are also presented and analyzed numerically. Conclusions are drawn, and recommendations are made. A derivation of the steady-state solution is given in the Appendix.

  9. 'Do Not Attempt Cardiopulmonary Resuscitation' discussions at the point of discharge: a case note review of hospice practice following local integrated policy implementation.

    PubMed

    Hall, Charlie Christopher; Mark, Kathleen; Oxenham, David; Spiller, Juliet Anne

    2011-09-01

    An integrated 'Do Not Attempt Cardiopulmonary Resuscitation' (DNACPR) policy was implemented across Lothian in 2006 (for ease of reading the terminology 'DNACPR' has been used throughout the paper where the original Lothian Policy used 'DNAR'). Patients were, for the first time, able to be discharged home with their DNACPR form after discussion about cardiopulmonary resuscitation (CPR). To ascertain the number of patients who, following a discussion, were discharged with a DNACPR form and the reasons for not holding discussions with certain patients. Two retrospective case note reviews of 50 patients discharged over two 4-month periods (2007 and 2009). There was a high proportion (78-80%) of CPR discussions for patients discharged from the hospice. Reasons for not discussing CPR were: potential for excess distress (10-12% 2007 and 2009) and lack of time (4% both years). Of those discussing CPR on discharge, 90% took forms home in both years. The reasons patients did not take forms home were: form not taken in error (two patients in 2007); patients refusing a form at home (one and three patients in 2007 and 2009); form to be arranged by general practitioner and one incomplete discussion. The proportion of patients with forms already at home increased from 10% (2007) to 28% (2009). It is possible to discuss CPR with a high proportion of hospice patients prior to discharge from a hospice. Following the introduction of an integrated policy, more patients have DNACPR forms prior to admission. Most patients receiving specialist palliative care find DNACPR discussions acceptable and understand the benefits of having a DNACPR form.

  10. Fortune telling addiction: Unfortunately a serious topic about a case report.

    PubMed

    Grall-Bronnec, Marie; Bulteau, Samuel; Victorri-Vigneau, Caroline; Bouju, Gaëlle; Sauvaget, Anne

    2015-03-01

    Constant social change brings about new forms of behavior, such as smartphone use, social networking,indoor tanning, cosmetic surgery, etc., that could become excessive or even lead to new forms of addictive disorders. We report the case of a woman who starts consulting for “clairvoyance addiction”. We then discuss the addictive nature of her disorder, based on several classifications of addiction. The patient fulfilled the criteria for addiction and her clinical features were typical of that of addicted people. Other differential diagnoses were discussed. As for any addictive behavior, the interaction of several risk factors should be considered.They are related to the individual himself, but also to the object of addiction and to the socio-environmental context. In this case, all the conditions were met for fortune telling use to become addictive.

  11. The general Lie group and similarity solutions for the one-dimensional Vlasov-Maxwell equations

    NASA Technical Reports Server (NTRS)

    Roberts, D.

    1985-01-01

    The general Lie point transformation group and the associated reduced differential equations and similarity forms for the solutions are derived here for the coupled (nonlinear) Vlasov-Maxwell equations in one spatial dimension. The case of one species in a background is shown to admit a larger group than the multispecies case. Previous exact solutions are shown to be special cases of the above solutions, and many of the new solutions are found to constrain the form of the distribution function much more than, for example, the BGK solutions do. The individual generators of the Lie group are used to find the possible subgroups. Finally, a simple physical argument is given to show that the asymptotic solution for a one-species, one-dimensional plasma is one of the general similarity solutions.

  12. Lumbosacral transitional vertebra causing Bertolotti’s syndrome: a case report and review of the literature

    PubMed Central

    Koutras, Georgios; Natsis, Konstantinos

    2009-01-01

    Introduction Lumbosacral transitional vertebra is an anatomical variation of the fifth lumbar vertebra in which an enlarged transverse process can form a joint or fusion with the sacrum or ilium. The association of that variant with low back pain and the change in the biomechanical properties of the lumbar spine is called Bertolotti’s syndrome. Case presentation We report a case of a 40-year-old male patient with chronic low back pain extending to the left buttock, just above the ipsilateral sacroiliac joint. Radiographic investigation revealed an anomalous enlargement of the left transverse process of the fifth lumbar vertebra forming a pseudarthrosis with the infrajacent ala of the sacrum. Conclusion In young patients with back pain the possibility of Bertolotti’s syndrome should always be taken in account. PMID:19830065

  13. On equations of motion of a nonlinear hydroelastic structure

    NASA Astrophysics Data System (ADS)

    Plotnikov, P. I.; Kuznetsov, I. V.

    2008-07-01

    Formal derivation of equations of a nonlinear hydroelastic structure, which is a volume of an ideal incompressible fluid covered by a shell, is proposed. The study is based on two assumptions. The first assumption implies that the energy stored in the shell is completely determined by the mean curvature and by the elementary area. In a three-dimensional case, the energy stored in the shell is chosen in the form of the Willmore functional. In a two-dimensional case, a more generic form of the functional can be considered. The second assumption implies that the equations of motionhave a Hamiltonian structure and can be obtained from the Lagrangian variational principle. In a two-dimensional case, a condition for the hydroelastic structure is derived, which relates the external pressure and the curvature of the elastic shell.

  14. Fortune telling addiction: Unfortunately a serious topic. About a case report

    PubMed Central

    BULTEAU, SAMUEL; VICTORRI-VIGNEAU, CAROLINE; BOUJU, GAËLLE; SAUVAGET, ANNE

    2015-01-01

    Background Constant social change brings about new forms of behavior, such as smartphone use, social networking, indoor tanning, cosmetic surgery, etc., that could become excessive or even lead to new forms of addictive disorders. Methods We report the case of a woman who starts consulting for “clairvoyance addiction”. We then discuss the addictive nature of her disorder, based on several classifications of addiction. Results The patient fulfilled the criteria for addiction and her clinical features were typical of that of addicted people. Other differential diagnoses were discussed. Conclusion As for any addictive behavior, the interaction of several risk factors should be considered. They are related to the individual himself, but also to the object of addiction and to the socio-environmental context. In this case, all the conditions were met for fortune telling use to become addictive. PMID:25786497

  15. [Genetic approaches to Itsenko-Cushing disease].

    PubMed

    Kalinin, A P; Andrusenko, A B; Novikov, A V; Bogatyrev, O P; Donskov, S I; Borisova, M G; Kriukov, V F; Riazanova, L A; Manichkin, V N

    1993-01-01

    107 patients with Itsenko-Cushing disease were examined for heredity: family history was analyzed in 75 cases, dermatoglyphics was assessed in 44 cases, I- and II-class HLA antigens were studied in 68 cases. The patients were found to have hereditary loading both by Itsenko-Cushing and other diseases (hypertension, atherosclerosis, autoimmune disorders). Clinico-genealogical evaluation made it possible to identify forms of the disease which are inherited autosome-recessively and autosome-dominantly. However, in the majority of patients the disease onset had multifactorial nature, as there were HLA-antigen associations by DR4, DR5, DR7, DRw53, DQw3. Pilot experience with genetic study of the disease showed its genetic determination in some forms, its association with hypertension and atherosclerosis, approaches to prevention, prognosis, classification. Practical recommendations on detailed family history collection in patients with Itsenko-Cushing disease have been developed.

  16. Splash lubricating system for an engine

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nakano, K.; Tani, Y.; Umeda, T.

    1986-12-16

    A splash lubrication system is described for an engine comprising a crank case, a crank room formed in the crank case, an oil reserving room formed in a lower part of the crank case for lubricating oil, and an oil splasher. The splasher extends from a big end of a connecting rod downward so as to splash oil from the oil reserving room to the crank room on its way from a front side to a back side along the lower part of its orbit. The improvement described here comprises: a transverse partition substantially covering the oil reserving room, disposedmore » at an upper space thereof, having an opening which allows the oil splasher to move therein. It includes three buffer plates covering front, right and left sides of the opening respectively for controlling oil level thereunder.« less

  17. Generalized peeling skin syndrome: Case report and review of the literature.

    PubMed

    Kharfi, Monia; Khaled, Aida; Ammar, Donia; Ezzine, Nadia; El Fekih, Nadia; Fazaa, Becima; Jaafoura, Hiabib; Kamoun, Mohamed Ridha

    2010-03-15

    Peeling skin syndrome (PSS) is a rare form of ichthyosis with a probable autosomal recessive inheritance that exhibits superficial, painless, continual, or seasonal cutaneous exfoliation. The syndrome generally appears at birth or in infancy. We report a case of generalized PSS and provide a literature review. A 34-year-old woman reported a lifelong history of generalized and painless peeling of the skin that worsened in summer. Her parents were third degree cousins. Her twin sister and her two cousins presented with the same condition. Physical examination showed widespread superficial sheets of variable size that could be easily removed without bleeding or pain. No underlying erythema was noted. Otherwise, the patient was in good health. Histological findings showed an epidermal cleavage within the stratum corneum. The generalized form of PSS is classified into 3 types, A, B, and C, according to the classification system of Traupe and Mevorah. We have tried to classify the cases of generalized PSS already reported in the literature into one of these three types. Thirteen reported cases probably presented PSS-type A. Sixteen patients are best described as PSS-type B. Two patients exhibit PSS-type C. Fifteen reported patients had an acral form of peeling skin syndrome. The classification of the eleven remaining patients was difficult to determine. Our patient presented clinical and histological features of generalized PSS-type A.

  18. Identification of the first intragenic deletion of the PITX2 gene causing an Axenfeld-Rieger Syndrome: case report

    PubMed Central

    de la Houssaye, Guillaume; Bieche, Ivan; Roche, Olivier; Vieira, Véronique; Laurendeau, Ingrid; Arbogast, Laurence; Zeghidi, Hatem; Rapp, Philippe; Halimi, Philippe; Vidaud, Michel; Dufier, Jean-Louis; Menasche, Maurice; Abitbol, Marc

    2006-01-01

    Background Axenfeld-Rieger syndrome (ARS) is characterized by bilateral congenital abnormalities of the anterior segment of the eye associated with abnormalities of the teeth, midface, and umbilicus. Most cases of ARS are caused by mutations in the genes encoding PITX2 or FOXC1. Here we describe a family affected by a severe form of ARS. Case presentation Two members of this family (father and daughter) presented with typical ARS and developed severe glaucoma. The ocular phenotype was much more severe in the daughter than in the father. Magnetic resonance imaging (MRI) detected an aggressive form of meningioma in the father. There was no mutation in the PITX2 gene, determined by exon screening. We identified an intragenic deletion by quantitative genomic PCR analysis and characterized this deletion in detail. Conclusion Our findings implicate the first intragenic deletion of the PITX2 gene in the pathogenesis of a severe form of ARS in an affected family. This study stresses the importance of a systematic search for intragenic deletions in families affected by ARS and in sporadic cases for which no mutations in the exons or introns of PITX2 have been found. The molecular genetics of some ARS pedigrees should be re-examined with enzymes that can amplify medium and large genomic fragments. PMID:17134502

  19. Stamping of Thin-Walled Structural Components with Magnesium Alloy AZ31 Sheets

    NASA Astrophysics Data System (ADS)

    Chen, Fuh-Kuo; Chang, Chih-Kun

    2005-08-01

    In the present study, the stamping process for manufacturing cell phone cases with magnesium alloy AZ31 sheets was studied using both the experimental approach and the finite element analysis. In order to determine the proper forming temperature and set up a fracture criterion, tensile tests and forming limit tests were first conducted to obtain the mechanical behaviors of AZ31 sheets at various elevated temperatures. The mechanical properties of Z31 sheets obtained from the experiments were then adopted in the finite element analysis to investigate the effects of the process parameters on the formability of the stamping process of cell phone cases. The finite element simulation results revealed that both the fracture and wrinkle defects could not be eliminated at the same time by adjusting blank-holder force or blank size. A drawbead design was then performed using the finite element simulations to determine the size and the location of drawbead required to suppress the wrinkle defect. An optimum stamping process, including die geometry, forming temperature, and blank dimension, was then determined for manufacturing the cell phone cases. The finite element analysis was validated by the good agreement between the simulation results and the experimental data. It confirms that the cell phone cases can be produced with magnesium alloy AZ31 sheet by the stamping process at elevated temperatures.

  20. Multicentric Castleman's disease in human immunodeficiency virus infection: two case reports.

    PubMed

    Caroline Ribeiro Sales, Amanda; Romão de Souza Junior, Valter; Iglis de Oliveira, Marta; Azevedo Braga Albuquerque, Claudia; de Barros Campelo Júnior, Evônio; Sérgio Ramos de Araújo, Paulo

    2018-05-05

    Castleman's Disease is a rare B-cell lymphoproliferative disease. It is mostly benign and is characterized by non-neoplastic lymph node hypertrophy, associated with infection by human herpesvirus-8 in people with the human immunodeficiency virus/acquired immunodeficiency syndrome. Although the unicentric or localized form presents as benign, the multifocal form can manifest severe systemic symptoms. We report two unusual cases of men presenting cervical enlarged lymph nodes that were believed to be infectious. The first case is a 41-year-old feoderm man who presented to the Department of Infectious Diseases of the Hospital das Clínicas in May 2015, with irregular fever history (38-39 °C), dyspnea, weight loss (8 kg/1 year), and asthenia with increased cervical lymph nodes of 1-year duration. His immunohistochemical diagnosis presented Castleman's disease in plasmacytic/diffuse form. In the second case, a 35-year-old feoderm man presented at the same hospital with multiple cervical enlarged lymph nodes and histopathological evidence of Castleman's disease associated with human herpesvirus-8. Considering the importance of differential diagnosis of lymphoid disorders, Castleman's disease is a challenging diagnosis in people living with human immunodeficiency virus/acquired immunodeficiency syndrome and can be easily misdiagnosed when lymphoid disorders are present in the human immunodeficiency virus/acquired immunodeficiency syndrome population due to nonspecific symptoms and signs.

  1. Teaching Integer Operations Using Ring Theory

    ERIC Educational Resources Information Center

    Hirsch, Jenna

    2012-01-01

    A facility with signed numbers forms the basis for effective problem solving throughout developmental mathematics. Most developmental mathematics textbooks explain signed number operations using absolute value, a method that involves considering the problem in several cases (same sign, opposite sign), and in the case of subtraction, rewriting the…

  2. 14 CFR 16.223 - Evidence.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... shall be submitted in written form in advance of the oral hearing pursuant to the schedule established in the hearing officer's prehearing conference report. Written direct and rebuttal fact testimony... written testimony and evidence. Except in the case of evidence obtained by subpoena, or in the case of a...

  3. Prosecution's Power, Procedural Rights, and Pleading Guilty: The Problem of Coercion in Plea Bargaining Drug Cases.

    ERIC Educational Resources Information Center

    Cloyd, Jerald W.

    1979-01-01

    The forms of psychological pressure placed on the defendant's pleading in drug cases are examined, with emphasis on the interplay between rational and emotional aspects of such situations. Three stages in plea bargaining negotiations are outlined. (Author/MC)

  4. Acute polyradiculoneuritis in Sarajevo during the war.

    PubMed

    Delilović-Vranić, Jasminka; Dautović-Krkić, Sajma

    2006-02-01

    Acute polyradiuloneuritis is acute inflammatory demyelinizing polyneuropathy, with still unknown cause, and which main pathophysiological disorder is degeneration of axons which affects peripheral nerves. Most frequently it occurs as acute, several days or weeks after viral, respiratory or gastrointestinal infections. Survival rate is in the world between 95-98% of cases. The goal of the research is to determine by retrospective study number of cases of acute polyradiculoneuritis during the war in the Sarajevo under the siege and their outcome. In this paper we have analyzed total number of acute polyradiculoneuritis cases within the period since April 1992 until April 1996, when the city of Sarajevo was completely under siege. Diagnostic criteria's besides anamnesis was detailed neurological exam, blood tests, analysis of the cerebrospinal liquor, EMG, ECG and cardiac tests. Within the above mentioned period there was 17 cases of polyradiculoneuritis, 13 male and 4 females, age between 14-65 years. Motor weakness and parestesias was most dominant in clinical image. Number of cases increased during the years and it was greatest during 1995. Previous infections were noted in 6 cases, and 5 of those respiratory, and one case of gastrointestinal. Proteinorahia in liquor was found among 10 cases (4 during first and 6 during the second week of illness). Pathological EMG was found in 8 cases. Milder form of illness had 4 patients, while 13 patients had more severe form. In total 7 patients survived, 2 of them without consequences, 3 with milder and 2 with more severe consequences while in 10 cases there was a lethal outcome.

  5. HLA-DR-, CD33+, CD56+, CD16- myeloid/natural killer cell acute leukemia: a previously unrecognized form of acute leukemia potentially misdiagnosed as French-American-British acute myeloid leukemia-M3.

    PubMed

    Scott, A A; Head, D R; Kopecky, K J; Appelbaum, F R; Theil, K S; Grever, M R; Chen, I M; Whittaker, M H; Griffith, B B; Licht, J D

    1994-07-01

    We have identified and characterized a previously unrecognized form of acute leukemia that shares features of both myeloid and natural killer (NK) cells. From a consecutive series of 350 cases of adult de novo acute myeloid leukemia (AML), we identified 20 cases (6%) with a unique immunophenotype: CD33+, CD56+, CD11a+, CD13lo, CD15lo, CD34+/-, HLA-DR-, CD16-. Multicolor flow cytometric assays confirmed the coexpression of myeloid (CD33, CD13, CD15) and NK cell-associated (CD56) antigens in each case, whereas reverse transcription polymerase chain reaction (RT-PCR) assays confirmed the identity of CD56 (neural cell adhesion molecule) in leukemic blasts. Although two cases expressed CD4, no case expressed CD2, CD3, or CD8 and no case showed clonal rearrangement of genes encoding the T-cell receptor (TCR beta, gamma, delta). Leukemic blasts in the majority of cases shared unique morphologic features (deeply invaginated nuclear membranes, scant cytoplasm with fine azurophilic granularity, and finely granular Sudan black B and myeloperoxidase cytochemical reactivity) that were remarkably similar to those of acute promyelocytic leukemia (APL); particularly the microgranular variant (FAB AML-M3v). However, all 20 cases lacked the t(15;17) and 17 cases tested lacked the promyelocytic/retinoic acid receptor alpha (RAR alpha) fusion transcript in RT-PCR assays; 12 cases had 46,XX or 46,XY karyotypes, whereas 2 cases had abnormalities of chromosome 17q: 1 with del(17)(q25) and the other with t(11;17)(q23;q21) and the promyelocytic leukemia zinc finger/RAR alpha fusion transcript. All cases tested (6/20), including the case with t(11;17), failed to differentiate in vitro in response to all-trans retinoic acid (ATRA), suggesting that these cases may account for some APLs that have not shown a clinical response to ATRA. Four of 6 cases tested showed functional NK cell-mediated cytotoxicity, suggesting a relationship between these unique CD33+, CD56+, CD16- acute leukemias and normal CD56+, CD16- NK precursor cells. Using a combination of panning and multiparameter flow cytometric sorting, we identified a normal CD56+, CD33+, CD16- counterpart cell at a frequency of 1% to 2% in the peripheral blood of healthy individuals. Our studies suggest that this form of acute leukemia may arise from transformation of a precursor cell common to both the myeloid and NK cell lineages; thus we propose the designation myeloid/NK acute leukemia. Recognition of this new leukemic entity will be important in distinguishing these ATRA-nonresponsive cases from ATRA-responsive true APL.

  6. Business Case Analysis Of Small Modular Reactors (SMR) For DOD Assured Power

    DTIC Science & Technology

    2017-12-01

    Smith Second Reader: Thomas L. Albright THIS PAGE INTENTIONALLY LEFT BLANK i REPORT DOCUMENTATION PAGE Form Approved OMB No. 0704-0188 Public...SECURITY CLASSIFICATION OF ABSTRACT Unclassified 20. LIMITATION OF ABSTRACT UU NSN 7540-01-280-5500 Standard Form 298 (Rev. 2-89...attack (EMP) represents one of the most devastating forms of attack on the power grid. Because the North American grid is made up of three major

  7. Correction of high amounts of astigmatism through orthokeratology. A case report

    PubMed Central

    Baertschi, Michael; Wyss, Michael

    2011-01-01

    The purpose of this case report is to introduce a method for a successful treatment of high astigmatism with a new orthokeratology design, called FOKX (Falco Kontaktlinsen, Switzerland). This novel toric orthokeratology contact lens design, the fitting approach and the performance of FOKX lenses will be illustrated in the form of a case report. Correcting astigmatism with orthokeratology offers a new perspective for all patients suffering astigmatism.

  8. Pan-brachial plexus neuropraxia following lightning: A rare case report.

    PubMed

    Patnaik, Ashis; Mahapatra, Ashok Kumar; Jha, Menka

    2015-01-01

    Neurological complications following lightning are rare and occur in form of temporary neurological deficits of central origin. Involvement of peripheral nervous system is extremely rare and only a few cases have been described in the literature. Isolated unilateral pan-brachial plexus neuropraxia has never been reported in the literature. Steroids have long been used for treatment of neuropraxia. However, their use in lightning neural injury is unique and requires special mention. We report a rare case of lightning-induced unilateral complete flaccid paralysis along with sensory loss in a young patient. Lightning typically causes central nervous involvement in various types of motor and sensory deficit. Surprisingly, the nerve conduction study showed the involvement of peripheral nervous system involvement. Steroids were administered and there was significant improvement in neurological functions within a short span of days. Patients' functions in the affected limb were normal in one month. Our case was interesting since it is the first such case in the literature where lightning has caused such a rare instance of unilateral pan-brachial plexus lesion. Such cases when seen, raises the possibility of more common central nervous system pathology rather than peripheral involvement. However, such lesions can be purely benign forms of peripheral nerve neuropraxia, which can be managed by steroid treatment without leaving any long-term neurological deficits.

  9. Caspase-6 Activation in Familial Alzheimer Disease Brains Carrying Amyloid Precursor Protein, Presenilin I or Presenilin II Mutations

    PubMed Central

    Albrecht, Steffen; Bogdanovic, Nenad; Ghetti, Bernardino; Winblad, Bengt; LeBlanc, Andréa C.

    2010-01-01

    We previously demonstrated the activation of Caspase-6 in the hippocampus and cortex in cases of mild, moderate, severe and very severe Alzheimer disease (AD). To determine whether Caspase-6 is also activated in familial AD, we performed an immunohistochemical analysis of active Caspase-6 and Tau cleaved by Caspase-6 in temporal cortex and hippocampal tissue sections from cases of familial AD. The cases included 5 carrying the amyloid precursor protein K670N, M671L Swedish mutation, 1 carrying the amyloid precursor protein E693G Arctic mutation, 2 each carrying the Presenilin I M146V, F105L, A431E, V261F, Y115C mutations, and 1 with the Presenilin II N141I mutation. Active Caspase-6 immunoreactivity was found in all cases. Caspase-6 immunoreactivity was observed in neuritic plaques or cotton wool plaques in some cases, neuropil threads and neurofibrillary tangles. These results indicate that Caspase-6 is activated in familial forms of AD, as previously observed in sporadic forms. Since sporadic and familial AD cases have similar pathological features, these results support a fundamental role of Caspase-6 in the pathophysiology of both familial and sporadic AD. PMID:19915487

  10. A closed form slug test theory for high permeability aquifers.

    PubMed

    Ostendorf, David W; DeGroot, Don J; Dunaj, Philip J; Jakubowski, Joseph

    2005-01-01

    We incorporate a linear estimate of casing friction into the analytical slug test theory of Springer and Gelhar (1991) for high permeability aquifers. The modified theory elucidates the influence of inertia and casing friction on consistent, closed form equations for the free surface, pressure, and velocity fluctuations for overdamped and underdamped conditions. A consistent, but small, correction for kinetic energy is included as well. A characteristic velocity linearizes the turbulent casing shear stress so that an analytical solution for attenuated, phase shifted pressure fluctuations fits a single parameter (damping frequency) to transducer data from any depth in the casing. Underdamped slug tests of 0.3, 0.6, and 1 m amplitudes at five transducer depths in a 5.1 cm diameter PVC well 21 m deep in the Plymouth-Carver Aquifer yield a consistent hydraulic conductivity of 1.5 x 10(-3) m/s. The Springer and Gelhar (1991) model underestimates the hydraulic conductivity for these tests by as much as 25% by improperly ascribing smooth turbulent casing friction to the aquifer. The match point normalization of Butler (1998) agrees with our fitted hydraulic conductivity, however, when friction is included in the damping frequency. Zurbuchen et al. (2002) use a numerical model to establish a similar sensitivity of hydraulic conductivity to nonlinear casing friction.

  11. Characterizing AISI 1045 steel surface duplex-treated by alternating current field enhanced pack aluminizing and nitriding

    NASA Astrophysics Data System (ADS)

    Xie, Fei; Zhang, Ge; Pan, Jianwei

    2018-02-01

    Thin cases and long treating time are shortcomings of conventional duplex treatment of aluminizing followed by nitriding (DTAN). Alternating current field (ACF) enhanced DTAN was carried out on AISI 1045 steel by applying an ACF to treated samples and treating agents with a pair of electrodes for overcoming those shortcomings. By investigating cases' structures, phases, composition and hardness distributions of differently treated samples, preliminary studies were made on characterizations of the ACF enhanced duplex treatment to AISI 1045 steel. The results show that, with the help of the ACF, the surface Al-rich phase Al5Fe2 formed in conventional pack aluminizing can be easily avoided and the aluminizing process is dramatically promoted. The aluminizing case can be nitrided either with conventional pack nitriding or ACF enhanced pack nitriding. By applying ACF to pack nitriding, the diffusion of nitrogen into the aluminizing case is promoted. AlN, Fe2∼3N and solid solution of N in iron are efficiently formed as a result of reactions of N with the aluminizing case. A duplex treated case with an effective thickness of more than 170 μm can be obtained by the alternating current field enhanced 4 h pack aluminizing plus 4 h pack nitriding.

  12. Solid intraocular xanthogranuloma in three Miniature Schnauzer dogs.

    PubMed

    Zarfoss, Mitzi K; Dubielzig, Richard R

    2007-01-01

    Macrophages that contain abundant intracytoplasmic lipid are called 'foam cells'. In four canine globes submitted to the Comparative Ocular Pathology Laboratory of Wisconsin (COPLOW), foam cells formed a solid intraocular mass. The purpose of this study was to describe the histopathologic findings in these cases. The electronic COPLOW database (1993-2006) was searched for the diagnosis of 'foam cell tumor'. Clinical history, gross pathology and histopathology (5-micron sections, hematoxylin and eosin and Alcian blue periodic acid Schiff) were reviewed in all cases. Cases were included if the globe was grossly filled by a solid mass and if all intraocular structures were effaced by lipid-laden foam cell macrophages admixed with birefringent, Alcian blue-positive crystals oriented in stellate patterns. All three patients (four globes) satisfying the selection criteria were Miniature Schnauzers. In all cases the clinical history included diabetes mellitus, hyperlipidemia and chronic bilateral uveitis that was interpreted to be lens-induced. All globes were enucleated because of glaucoma. The term solid intraocular xanthogranuloma was used to describe these cases because the intraocular contents were effaced by a solid mass of foam cells and birefringent crystals. The cases in this report suggest that diabetic Miniature Schnauzers with hyperlipidemia are at risk for lipid and macrophage-rich uveitis, which may in some cases form a solid inflammatory intraocular mass, precipitate glaucoma, and lead to enucleation.

  13. Uses of chitosan for treating different forms of serious obstetrics hemorrhages.

    PubMed

    Carles, G; Dabiri, C; Mchirgui, A; Saoudi, E O; Hcini, N; Pouget, K; Seve, B; de Matteis, B

    2017-11-01

    Postpartum hemorrhage is a major cause of maternal death worldwide. Many therapeutic strategies have been developed to reduce maternal morbidity and mortality like oxytocin, prostaglandin, and uterine balloons. A new member of the therapeutic arsenal has recently emerged, the chitosan (Celox ® ), used since several years by military doctors to stop bleeding of combat wounds. In 2012, a first study was reported with the successful use of chitosan-coated gauze to treat severe postpartum hemorrhage. We report here four cases of the use of chitosan to treat life-threatening obstetric bleeding. In the first case, a pelvic packing with chitosan gauze after hemostatic hysterectomy with persistent bleeding. In the second case, the use of chitosan powder in a case of severe bleeding from multiple vaginal tears. In the third case, the use of chitosan gauze in uterine packing for postpartum hemorrhage by atonia. In the fourth case, the use of chitosan powder for stop bleeding during a hemorrhagic cesarean section. Postpartum hemorrhage of uterine origin resistant to treatment with prostaglandins can be treated with chitosan-coated gauze. This treatment requires no training and its costs are one fifth those of a Bakri ® intrauterine balloon. Using these two forms of chitosan, powder and gauze, we have a new therapeutic method at our disposal for dealing with the most serious cases of bleeding. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  14. Update: Dura Mater Graft-Associated Creutzfeldt-Jakob Disease - Japan, 1975-2017.

    PubMed

    Ae, Ryusuke; Hamaguchi, Tsuyoshi; Nakamura, Yosikazu; Yamada, Masahito; Tsukamoto, Tadashi; Mizusawa, Hidehiro; Belay, Ermias D; Schonberger, Lawrence B

    2018-03-09

    Creutzfeldt-Jakob disease (CJD) is a fatal neurodegenerative disorder that, according to the most well accepted hypothesis (1), is caused by replicating, transmissible, abnormal forms of a host-encoded prion protein (prions). Most CJD cases occur spontaneously (sporadic CJD) or are inherited (genetic CJD). Iatrogenic CJD can occur after exposure to prion-contaminated instruments or products in medical/surgical settings. Cadaveric dura mater graft-associated CJD (dCJD) accounts for a common form of iatrogenic CJD. This report summarizes the epidemiologic features of 154 cases of dCJD identified in Japan during 1975-2017; these cases account for >60% of dCJD cases reported worldwide (1,2). The unusually high prevalence of dCJD in Japan was first reported in 1997 (3). In 2008, a single brand of graft (Lyodura [B. Braun Melsungen AG, Melsungen, Germany]), frequently used as a patch in neurosurgical procedures, was identified as the probable vehicle of transmission (4). No international recall of the implicated Lyodura occurred, the product had a relatively long shelf life, and the grafts were used frequently in Japanese patients with non-life-threatening conditions (4,5). Since 2008, additional cases have been ascertained, reflecting the identification of previously missed cases and the occurrence of new cases with longer latency periods (interval from exposure to symptom onset) for dCJD (up to 30 years), underscoring the importance of maintaining surveillance for dCJD.

  15. Torts.

    ERIC Educational Resources Information Center

    Evans, William J., Jr.

    This chapter examines cases reported during 1990 that involved tort claims within the school context. A tort is a civil wrong, other than breach of contract, for which a court provides relief in the form of damages. Included are cases involving school officials, school employees, students, and in some instances others visiting school grounds. Tort…

  16. The Case for Common Examinations. Carnegie Perspectives

    ERIC Educational Resources Information Center

    Bond, Lloyd

    2007-01-01

    Through an examination of one institution's efforts to strengthen teaching and learning on campus, the author makes a strong case for the use of common examinations as a powerful form of assessment as well as a fruitful context for faculty deliberations. Providing a continuing occasion for faculty inquiry and discussion, insuring grade…

  17. 26 CFR 1.6091-4 - Exceptional cases.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...) INCOME TAXES Place for Filing Returns Or Other Documents § 1.6091-4 Exceptional cases. (a) Permission to... proper attachment to, or is, a return which the service center is expressly authorized to receive, such... corporation with its principal place of business in Greensboro, North Carolina, is required to file its Form...

  18. Team Assessment of Geriatric Mental Patients: The Care of Functional Dementia Produced by Hysterical Behavior.

    ERIC Educational Resources Information Center

    Kirby, Henry B.; Harper, Robert G.

    1987-01-01

    Multidisciplinary team identified hysterical behavior, rather than depression, as one form of pseudodementia in many cases of cognitive impairment observed in geriatric patients. Seven cases required thorough medical and neuropsychological assessment and careful functional analysis of patients' behavior patterns to determine the adaptive utility…

  19. 7 CFR 765.205 - Subordination of liens.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... time and has a definite maturity date; (13) In the case of real property purchase or exchange, the... Subordination of liens. (a) Borrower application requirements. The borrower must submit the following, unless it... application for subordination form; (2) A current financial statement, including, in the case of an entity...

  20. Issues in Retrospective Conversion for a Small Special Collection: A Case Study.

    ERIC Educational Resources Information Center

    Hieb, Fern

    1997-01-01

    Small special collections present unique problems for retrospective conversion of catalogs to machine-readable form. Examines retrospective conversion using the Moravian Music Foundation as a case study. Discusses advantages to automation, options for conversion process, quantifying conversion effort, costs, in-house conversion, national standards…

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