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Sample records for fixed point unravelling

  1. Fixed points of quantum gravity.

    PubMed

    Litim, Daniel F

    2004-05-21

    Euclidean quantum gravity is studied with renormalization group methods. Analytical results for a nontrivial ultraviolet fixed point are found for arbitrary dimensions and gauge fixing parameters in the Einstein-Hilbert truncation. Implications for quantum gravity in four dimensions are discussed.

  2. Renormalization Group Trajectories Between Two Fixed Points

    NASA Astrophysics Data System (ADS)

    Abdesselam, Abdelmalek

    2010-03-01

    We report on our recent rigorous construction of complete renormalization group trajectories between two fixed points for the three-dimensional phi-four model with modified propagator considered by Brydges, Mitter and Scoppola (BMS). These are discrete critical trajectories which connect the ultraviolet Gaussian fixed point to the nontrivial BMS infrared fixed point which is an analogue of the Wilson-Fisher fixed point. The renormalization group map is defined rigorously and nonperturbatively, without using the hierarchical approximation. The trajectories are constructed by a fixed point argument in a suitable Banach space of sequences, where one perturbs a nonlinear one-dimensional iteration.

  3. Anderson Acceleration for Fixed-Point Iterations

    SciTech Connect

    Walker, Homer F.

    2015-08-31

    The purpose of this grant was to support research on acceleration methods for fixed-point iterations, with applications to computational frameworks and simulation problems that are of interest to DOE.

  4. Characterizations of fixed points of quantum operations

    SciTech Connect

    Li Yuan

    2011-05-15

    Let {phi}{sub A} be a general quantum operation. An operator B is said to be a fixed point of {phi}{sub A}, if {phi}{sub A}(B)=B. In this note, we shall show conditions under which B, a fixed point {phi}{sub A}, implies that B is compatible with the operation element of {phi}{sub A}. In particular, we offer an extension of the generalized Lueders theorem.

  5. Gravitational Fixed Points from Perturbation Theory

    SciTech Connect

    Niedermaier, Max R.

    2009-09-04

    The fixed point structure of the renormalization flow in higher derivative gravity is investigated in terms of the background covariant effective action using an operator cutoff that keeps track of powerlike divergences. Spectral positivity of the gauge fixed Hessian can be satisfied upon expansion in the asymptotically free higher derivative coupling. At one-loop order in this coupling strictly positive fixed points are found for the dimensionless Newton constant g{sub N} and the cosmological constant lambda, which are determined solely by the coefficients of the powerlike divergences. The renormalization flow is asymptotically safe with respect to this fixed point and settles on a lambda(g{sub N}) trajectory after O(10) units of the renormalization mass scale to accuracy 10{sup -7}.

  6. Gravitational fixed points from perturbation theory.

    PubMed

    Niedermaier, Max R

    2009-09-01

    The fixed point structure of the renormalization flow in higher derivative gravity is investigated in terms of the background covariant effective action using an operator cutoff that keeps track of powerlike divergences. Spectral positivity of the gauge fixed Hessian can be satisfied upon expansion in the asymptotically free higher derivative coupling. At one-loop order in this coupling strictly positive fixed points are found for the dimensionless Newton constant g(N) and the cosmological constant lambda, which are determined solely by the coefficients of the powerlike divergences. The renormalization flow is asymptotically safe with respect to this fixed point and settles on a lambda(g(N)) trajectory after O(10) units of the renormalization mass scale to accuracy 10(-7).

  7. Quantum entanglement and fixed-point bifurcations

    SciTech Connect

    Hines, Andrew P.; McKenzie, Ross H.; Milburn, G.J.

    2005-04-01

    How does the classical phase-space structure for a composite system relate to the entanglement characteristics of the corresponding quantum system? We demonstrate how the entanglement in nonlinear bipartite systems can be associated with a fixed-point bifurcation in the classical dynamics. Using the example of coupled giant spins we show that when a fixed point undergoes a supercritical pitchfork bifurcation, the corresponding quantum state--the ground state--achieves its maximum amount of entanglement near the critical point. We conjecture that this will be a generic feature of systems whose classical limit exhibits such a bifurcation.

  8. Precise Point Positioning with Partial Ambiguity Fixing

    PubMed Central

    Li, Pan; Zhang, Xiaohong

    2015-01-01

    Reliable and rapid ambiguity resolution (AR) is the key to fast precise point positioning (PPP). We propose a modified partial ambiguity resolution (PAR) method, in which an elevation and standard deviation criterion are first used to remove the low-precision ambiguity estimates for AR. Subsequently the success rate and ratio-test are simultaneously used in an iterative process to increase the possibility of finding a subset of decorrelated ambiguities which can be fixed with high confidence. One can apply the proposed PAR method to try to achieve an ambiguity-fixed solution when full ambiguity resolution (FAR) fails. We validate this method using data from 450 stations during DOY 021 to 027, 2012. Results demonstrate the proposed PAR method can significantly shorten the time to first fix (TTFF) and increase the fixing rate. Compared with FAR, the average TTFF for PAR is reduced by 14.9% for static PPP and 15.1% for kinematic PPP. Besides, using the PAR method, the average fixing rate can be increased from 83.5% to 98.2% for static PPP, from 80.1% to 95.2% for kinematic PPP respectively. Kinematic PPP accuracy with PAR can also be significantly improved, compared to that with FAR, due to a higher fixing rate. PMID:26067196

  9. Secure Computation with Fixed-Point Numbers

    NASA Astrophysics Data System (ADS)

    Catrina, Octavian; Saxena, Amitabh

    Secure computation is a promising approach to business problems in which several parties want to run a joint application and cannot reveal their inputs. Secure computation preserves the privacy of input data using cryptographic protocols, allowing the parties to obtain the benefits of data sharing and at the same time avoid the associated risks. These business applications need protocols that support all the primitive data types and allow secure protocol composition and efficient application development. Secure computation with rational numbers has been a challenging problem. We present in this paper a family of protocols for multiparty computation with rational numbers using fixed-point representation. This approach offers more efficient solutions for secure computation than other usual representations.

  10. Strongly coupled fixed point in φ 4 theory

    NASA Astrophysics Data System (ADS)

    Hegg, Anthony; Phillips, Philip W.

    2016-07-01

    We show explicitly how a fixed point can be constructed in scalar g\\varphi4 theory from the solutions to a nonlinear eigenvalue problem. The fixed point is unstable and characterized by ν=2/d (correlation length exponent), η=1/2-d/8 (anomalous dimension). For d = 2, these exponents reproduce to those of the Ising model which can be understood from the codimension of the critical point. The testable prediction of this fixed point is that the specific heat exponent vanishes. 2d critical Mott systems are well described by this new fixed point.

  11. Floating-to-Fixed-Point Conversion for Digital Signal Processors

    NASA Astrophysics Data System (ADS)

    Menard, Daniel; Chillet, Daniel; Sentieys, Olivier

    2006-12-01

    Digital signal processing applications are specified with floating-point data types but they are usually implemented in embedded systems with fixed-point arithmetic to minimise cost and power consumption. Thus, methodologies which establish automatically the fixed-point specification are required to reduce the application time-to-market. In this paper, a new methodology for the floating-to-fixed point conversion is proposed for software implementations. The aim of our approach is to determine the fixed-point specification which minimises the code execution time for a given accuracy constraint. Compared to previous methodologies, our approach takes into account the DSP architecture to optimise the fixed-point formats and the floating-to-fixed-point conversion process is coupled with the code generation process. The fixed-point data types and the position of the scaling operations are optimised to reduce the code execution time. To evaluate the fixed-point computation accuracy, an analytical approach is used to reduce the optimisation time compared to the existing methods based on simulation. The methodology stages are described and several experiment results are presented to underline the efficiency of this approach.

  12. Krasnoselski Mann iteration for hierarchical fixed-point problems

    NASA Astrophysics Data System (ADS)

    Moudafi, Abdellatif

    2007-08-01

    This paper deals with a method for approximating a solution of the following fixed-point problem: find \\tilde{x} \\in {\\cal H}; \\tilde{x} = (proj_{Fix(T)} \\circ P) \\tilde{x} , where {\\cal H} is a Hilbert space, P and T are two nonexpansive mappings on a closed convex subset D and projFix(T) denotes the metric projection on the set of fixed points of T. This amounts to saying that \\tilde{x} is the fixed point of T which satisfies a variational inequality depending on a given criterion P, namely: find \\tilde{x} \\in {\\cal H}; 0\\in (I-P)\\tilde{x}+N_{ Fix(T)}\\tilde{x} , where NFix(T) denotes the normal cone to the set of fixed points of T. Convergence results for the proposed method are proved. It should be noted that the proposed method can be regarded as a generalized version of Krasnoselski-Mann's iteration for solving a broader class of problems than the original KM algorithm, namely hierarchical fixed-point problems. This class is very interesting because it covers monotone variational inequality on fixed-point sets, minimization problems over equilibrium constraints, hierarchical minimization problems,.... The special aspect of the algorithm together with convergence results makes it an original and theoretically interesting scheme. On the other hand, the framework is general enough and permits us to treat in a unified way several iterative schemes, recovering, developing and improving some known related convergence results in this field.

  13. Fixed points for weakly inward mappings in Banach spaces

    NASA Astrophysics Data System (ADS)

    Xu, Shaoyuan; Jia, Baoguo; Li, Guo-Zhen

    2006-07-01

    S. Hu and Y. Sun [S. Hu, Y. Sun, Fixed point index for weakly inward mappings, J. Math. Anal. Appl. 172 (1993) 266-273] defined the fixed point index for weakly inward mappings, investigated its properties and studied the fixed points for such mappings. In this paper, following S. Hu and Y. Sun, we continue to investigate boundary conditions, under which the fixed point index for the completely continuous and weakly inward mapping, denoted by i(A,[Omega],P), is equal to 1 or 0. Correspondingly, we can obtain some new fixed point theorems of the completely continuous and weakly inward mappings and existence theorems of solutions for the equations Ax=[mu]x, which extend many famous theorems such as Leray-Schauder's theorem, Rothe's two theorems, Krasnoselskii's theorem, Altman's theorem, Petryshyn's theorem, etc., to the case of weakly inward mappings. In addition, our conclusions and methods are different from the ones in many recent works.

  14. A new compact fixed-point blackbody furnace

    SciTech Connect

    Hiraka, K.; Oikawa, H.; Shimizu, T.; Kadoya, S.; Kobayashi, T.; Yamada, Y.; Ishii, J.

    2013-09-11

    More and more NMIs are realizing their primary scale themselves with fixed-point blackbodies as their reference standard. However, commercially available fixed-point blackbody furnaces of sufficient quality are not always easy to obtain. CHINO Corp. and NMIJ, AIST jointly developed a new compact fixed-point blackbody furnace. The new furnace has such features as 1) improved temperature uniformity when compared to previous products, enabling better plateau quality, 2) adoption of the hybrid fixed-point cell structure with internal insulation to improve robustness and thereby to extend lifetime, 3) easily ejectable and replaceable heater unit and fixed-point cell design, leading to reduced maintenance cost, 4) interchangeability among multiple fixed points from In to Cu points. The replaceable cell feature facilitates long term maintenance of the scale through management of a group of fixed-point cells of the same type. The compact furnace is easily transportable and therefore can also function as a traveling standard for disseminating the radiation temperature scale, and for maintaining the scale at the secondary level and industrial calibration laboratories. It is expected that the furnace will play a key role of the traveling standard in the anticipated APMP supplementary comparison of the radiation thermometry scale.

  15. 47 CFR 101.137 - Interconnection of private operational fixed point-to-point microwave stations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... point-to-point microwave stations. 101.137 Section 101.137 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES FIXED MICROWAVE SERVICES Technical Standards § 101.137 Interconnection of private operational fixed point-to-point microwave stations....

  16. 47 CFR 101.137 - Interconnection of private operational fixed point-to-point microwave stations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... point-to-point microwave stations. 101.137 Section 101.137 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES FIXED MICROWAVE SERVICES Technical Standards § 101.137 Interconnection of private operational fixed point-to-point microwave stations....

  17. 47 CFR 101.137 - Interconnection of private operational fixed point-to-point microwave stations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... point-to-point microwave stations. 101.137 Section 101.137 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES FIXED MICROWAVE SERVICES Technical Standards § 101.137 Interconnection of private operational fixed point-to-point microwave stations....

  18. 47 CFR 101.137 - Interconnection of private operational fixed point-to-point microwave stations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... point-to-point microwave stations. 101.137 Section 101.137 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES FIXED MICROWAVE SERVICES Technical Standards § 101.137 Interconnection of private operational fixed point-to-point microwave stations....

  19. 47 CFR 101.137 - Interconnection of private operational fixed point-to-point microwave stations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Interconnection of private operational fixed point-to-point microwave stations. 101.137 Section 101.137 Telecommunication FEDERAL COMMUNICATIONS....137 Interconnection of private operational fixed point-to-point microwave stations....

  20. Towards a complete renormalization group trajectory between two fixed points

    NASA Astrophysics Data System (ADS)

    Abdesselam, Abdelmalek

    2007-12-01

    We give a rigorous nonperturbative construction of a massless discrete trajectory for Wilson’s exact renormalization group. The model is a three dimensional Euclidean field theory with a modified free propagator. The trajectory realizes the mean field to critical crossover from the ultraviolet Gaussian fixed point to an analog recently constructed by Brydges, Mitter and Scoppola of the Wilson-Fisher nontrivial fixed point.

  1. Image integrity authentication scheme based on fixed point theory.

    PubMed

    Li, Xu; Sun, Xingming; Liu, Quansheng

    2015-02-01

    Based on the fixed point theory, this paper proposes a new scheme for image integrity authentication, which is very different from digital signature and fragile watermarking. By the new scheme, the sender transforms an original image into a fixed point image (very close to the original one) of a well-chosen transform and sends the fixed point image (instead of the original one) to the receiver; using the same transform, the receiver checks the integrity of the received image by testing whether it is a fixed point image and locates the tampered areas if the image has been modified during the transmission. A realization of the new scheme is based on Gaussian convolution and deconvolution (GCD) transform, for which an existence theorem of fixed points is proved. The semifragility is analyzed via commutativity of transforms, and three commutativity theorems are found for the GCD transform. Three iterative algorithms are presented for finding a fixed point image with a few numbers of iterations, and for the whole procedure of image integrity authentication; a fragile authentication system and a semifragile one are separately built. Experiments show that both the systems have good performance in transparence, fragility, security, and tampering localization. In particular, the semifragile system can perfectly resist the rotation by a multiple of 90° flipping and brightness attacks.

  2. Contractive multifunctions, fixed point inclusions and iterated multifunction systems

    NASA Astrophysics Data System (ADS)

    Kunze, H. E.; La Torre, D.; Vrscay, E. R.

    2007-06-01

    We study the properties of multifunction operators that are contractive in the Covitz-Nadler sense. In this situation, such operators T possess fixed points satisfying the relation x[set membership, variant]Tx. We introduce an iterative method involving projections that guarantees convergence from any starting point x0[set membership, variant]X to a point x[set membership, variant]XT, the set of all fixed points of a multifunction operator T. We also prove a continuity result for fixed point sets XT as well as a "generalized collage theorem" for contractive multifunctions. These results can then be used to solve inverse problems involving contractive multifunctions. Two applications of contractive multifunctions are introduced: (i) integral inclusions and (ii) iterated multifunction systems.

  3. Stray thermal influences in zinc fixed-point cells

    SciTech Connect

    Rudtsch, S.; Aulich, A.; Monte, C.

    2013-09-11

    The influence of thermal effects is a major uncertainty contribution to the calibration of Standard Platinum Resistance Thermometers (SPRTs) in fixed-point cells. Axial heat losses strongly depend on the fixed-point temperature, constructional details of cells and SPRTs and the resulting heat transfer between cell, thermometer, furnace and environment. At the zinc point contributions by heat conduction and thermal radiation must be considered. Although the measurement of temperature gradients in the re-entrant well of a fixed-point cell provides very important information about the influence of axial heat losses, further investigations are required for a reliable estimate of the resulting uncertainty contribution. It is shown that specific modifications of a zinc fixed-point cell, following generally accepted principles, may result in systematic deviations of the measured fixed-point temperatures larger than typically stated in the uncertainty budget of National Metrology Institutes (NMIs). The underlying heat transport processes are investigated and the consequences for the construction of zinc cells are discussed.

  4. Border collisions inside the stability domain of a fixed point

    NASA Astrophysics Data System (ADS)

    Avrutin, Viktor; Zhusubaliyev, Zhanybai T.; Mosekilde, Erik

    2016-05-01

    Recent studies on a power electronic DC/AC converter (inverter) have demonstrated that such systems may undergo a transition from regular dynamics (associated with a globally attracting fixed point of a suitable stroboscopic map) to chaos through an irregular sequence of border-collision events. Chaotic dynamics of an inverter is not suitable for practical purposes. However, the parameter domain in which the stroboscopic map has a globally attracting fixed point has generally been considered to be uniform and suitable for practical use. In the present paper we show that this domain actually has a complicated interior structure formed by boundaries defined by persistence border collisions. We describe a simple approach that is based on symbolic dynamics and makes it possible to detect such boundaries numerically. Using this approach we describe several regions in the parameter space leading to qualitatively different output signals of the inverter although all associated with globally attracting fixed points of the corresponding stroboscopic map.

  5. Fixed-Rate Compressed Floating-Point Arrays.

    PubMed

    Lindstrom, Peter

    2014-12-01

    Current compression schemes for floating-point data commonly take fixed-precision values and compress them to a variable-length bit stream, complicating memory management and random access. We present a fixed-rate, near-lossless compression scheme that maps small blocks of 4(d) values in d dimensions to a fixed, user-specified number of bits per block, thereby allowing read and write random access to compressed floating-point data at block granularity. Our approach is inspired by fixed-rate texture compression methods widely adopted in graphics hardware, but has been tailored to the high dynamic range and precision demands of scientific applications. Our compressor is based on a new, lifted, orthogonal block transform and embedded coding, allowing each per-block bit stream to be truncated at any point if desired, thus facilitating bit rate selection using a single compression scheme. To avoid compression or decompression upon every data access, we employ a software write-back cache of uncompressed blocks. Our compressor has been designed with computational simplicity and speed in mind to allow for the possibility of a hardware implementation, and uses only a small number of fixed-point arithmetic operations per compressed value. We demonstrate the viability and benefits of lossy compression in several applications, including visualization, quantitative data analysis, and numerical simulation.

  6. Fixed-Rate Compressed Floating-Point Arrays.

    PubMed

    Lindstrom, Peter

    2014-12-01

    Current compression schemes for floating-point data commonly take fixed-precision values and compress them to a variable-length bit stream, complicating memory management and random access. We present a fixed-rate, near-lossless compression scheme that maps small blocks of 4(d) values in d dimensions to a fixed, user-specified number of bits per block, thereby allowing read and write random access to compressed floating-point data at block granularity. Our approach is inspired by fixed-rate texture compression methods widely adopted in graphics hardware, but has been tailored to the high dynamic range and precision demands of scientific applications. Our compressor is based on a new, lifted, orthogonal block transform and embedded coding, allowing each per-block bit stream to be truncated at any point if desired, thus facilitating bit rate selection using a single compression scheme. To avoid compression or decompression upon every data access, we employ a software write-back cache of uncompressed blocks. Our compressor has been designed with computational simplicity and speed in mind to allow for the possibility of a hardware implementation, and uses only a small number of fixed-point arithmetic operations per compressed value. We demonstrate the viability and benefits of lossy compression in several applications, including visualization, quantitative data analysis, and numerical simulation. PMID:26356981

  7. Measurement of thermodynamic temperature of high temperature fixed points

    SciTech Connect

    Gavrilov, V. R.; Khlevnoy, B. B.; Otryaskin, D. A.; Grigorieva, I. A.; Samoylov, M. L.; Sapritsky, V. I.

    2013-09-11

    The paper is devoted to VNIIOFI's measurements of thermodynamic temperature of the high temperature fixed points Co-C, Pt-C and Re-C within the scope of the international project coordinated by the Consultative Committee for Thermometry working group 5 'Radiation Thermometry'. The melting temperatures of the fixed points were measured by a radiance mode radiation thermometer calibrated against a filter radiometer with known irradiance spectral responsivity via a high temperature black body. This paper describes the facility used for the measurements, the results and estimated uncertainties.

  8. Fixed Point Problems for Linear Transformations on Pythagorean Triples

    ERIC Educational Resources Information Center

    Zhan, M.-Q.; Tong, J.-C.; Braza, P.

    2006-01-01

    In this article, an attempt is made to find all linear transformations that map a standard Pythagorean triple (a Pythagorean triple [x y z][superscript T] with y being even) into a standard Pythagorean triple, which have [3 4 5][superscript T] as their fixed point. All such transformations form a monoid S* under matrix product. It is found that S*…

  9. Fixed point theorems for generalized contractions in ordered metric spaces

    NASA Astrophysics Data System (ADS)

    O'Regan, Donal; Petrusel, Adrian

    2008-05-01

    The purpose of this paper is to present some fixed point results for self-generalized contractions in ordered metric spaces. Our results generalize and extend some recent results of A.C.M. Ran, M.C. Reurings [A.C.M. Ran, MEC. Reurings, A fixed point theorem in partially ordered sets and some applications to matrix equations, Proc. Amer. Math. Soc. 132 (2004) 1435-1443], J.J. Nieto, R. Rodríguez-López [J.J. Nieto, R. Rodríguez-López, Contractive mapping theorems in partially ordered sets and applications to ordinary differential equations, Order 22 (2005) 223-239; J.J. Nieto, R. Rodríguez-López, Existence and uniqueness of fixed points in partially ordered sets and applications to ordinary differential equations, Acta Math. Sin. (Engl. Ser.) 23 (2007) 2205-2212], J.J. Nieto, R.L. Pouso, R. Rodríguez-López [J.J. Nieto, R.L. Pouso, R. Rodríguez-López, Fixed point theorem theorems in ordered abstract sets, Proc. Amer. Math. Soc. 135 (2007) 2505-2517], A. Petrusel, I.A. Rus [A. Petrusel, I.A. Rus, Fixed point theorems in ordered L-spaces, Proc. Amer. Math. Soc. 134 (2006) 411-418] and R.P. Agarwal, M.A. El-Gebeily, D. O'Regan [R.P. Agarwal, M.A. El-Gebeily, D. O'Regan, Generalized contractions in partially ordered metric spaces, Appl. Anal., in press]. As applications, existence and uniqueness results for Fredholm and Volterra type integral equations are given.

  10. Non-thermal fixed point in a holographic superfluid

    NASA Astrophysics Data System (ADS)

    Ewerz, Carlo; Gasenzer, Thomas; Karl, Markus; Samberg, Andreas

    2015-05-01

    We study the far-from-equilibrium dynamics of a (2 + 1)-dimensional super-fluid at finite temperature and chemical potential using its holographic description in terms of a gravitational system in 3 + 1 dimensions. Starting from various initial conditions corresponding to ensembles of vortex defects we numerically evolve the system to long times. At intermediate times the system exhibits Kolmogorov scaling the emergence of which depends on the choice of initial conditions. We further observe a universal late- time regime in which the occupation spectrum and different length scales of the superfluid exhibit scaling behaviour. We study these scaling laws in view of superfluid turbulence and interpret the universal late-time regime as a non-thermal fixed point of the dynamical evolution. In the holographic superfluid the non-thermal fixed point can be understood as a stationary point of the classical equations of motion of the dual gravitational description.

  11. Fixed-rate compressed floating-point arrays

    SciTech Connect

    Lindstrom, P.

    2014-03-30

    ZFP is a library for lossy compression of single- and double-precision floating-point data. One of the unique features of ZFP is its support for fixed-rate compression, which enables random read and write access at the granularity of small blocks of values. Using a C++ interface, this allows declaring compressed arrays (1D, 2D, and 3D arrays are supported) that through operator overloading can be treated just like conventional, uncompressed arrays, but which allow the user to specify the exact number of bits to allocate to the array. ZFP also has variable-rate fixed-precision and fixed-accuracy modes, which allow the user to specify a tolerance on the relative or absolute error.

  12. Fixed-rate compressed floating-point arrays

    2014-03-30

    ZFP is a library for lossy compression of single- and double-precision floating-point data. One of the unique features of ZFP is its support for fixed-rate compression, which enables random read and write access at the granularity of small blocks of values. Using a C++ interface, this allows declaring compressed arrays (1D, 2D, and 3D arrays are supported) that through operator overloading can be treated just like conventional, uncompressed arrays, but which allow the user tomore » specify the exact number of bits to allocate to the array. ZFP also has variable-rate fixed-precision and fixed-accuracy modes, which allow the user to specify a tolerance on the relative or absolute error.« less

  13. Gravity Duals of Lifshitz-Like Fixed Points

    SciTech Connect

    Kachru, Shamit; Liu, Xiao; Mulligan, Michael; /Stanford U., Phys. Dept. /SLAC

    2008-11-05

    We find candidate macroscopic gravity duals for scale-invariant but non-Lorentz invariant fixed points, which do not have particle number as a conserved quantity. We compute two-point correlation functions which exhibit novel behavior relative to their AdS counterparts, and find holographic renormalization group flows to conformal field theories. Our theories are characterized by a dynamical critical exponent z, which governs the anisotropy between spatial and temporal scaling t {yields} {lambda}{sup z}t, x {yields} {lambda}x; we focus on the case with z = 2. Such theories describe multicritical points in certain magnetic materials and liquid crystals, and have been shown to arise at quantum critical points in toy models of the cuprate superconductors. This work can be considered a small step towards making useful dual descriptions of such critical points.

  14. Gravity duals of Lifshitz-like fixed points

    NASA Astrophysics Data System (ADS)

    Kachru, Shamit; Liu, Xiao; Mulligan, Michael

    2008-11-01

    We find candidate macroscopic gravity duals for scale-invariant but non-Lorentz invariant fixed points, which do not have particle number as a conserved quantity. We compute two-point correlation functions which exhibit novel behavior relative to their AdS counterparts, and find holographic renormalization group flows to conformal field theories. Our theories are characterized by a dynamical critical exponent z, which governs the anisotropy between spatial and temporal scaling t→λzt, x→λx; we focus on the case with z=2. Such theories describe multicritical points in certain magnetic materials and liquid crystals, and have been shown to arise at quantum critical points in toy models of the cuprate superconductors. This work can be considered a small step towards making useful dual descriptions of such critical points.

  15. Fixed points, stable manifolds, weather regimes, and their predictability

    SciTech Connect

    Deremble, Bruno; D'Andrea, Fabio; Ghil, Michael

    2009-10-27

    In a simple, one-layer atmospheric model, we study the links between low-frequency variability and the model’s fixed points in phase space. The model dynamics is characterized by the coexistence of multiple ''weather regimes.'' To investigate the transitions from one regime to another, we focus on the identification of stable manifolds associated with fixed points. We show that these manifolds act as separatrices between regimes. We track each manifold by making use of two local predictability measures arising from the meteorological applications of nonlinear dynamics, namely, ''bred vectors'' and singular vectors. These results are then verified in the framework of ensemble forecasts issued from clouds (ensembles) of initial states. The divergence of the trajectories allows us to establish the connections between zones of low predictability, the geometry of the stable manifolds, and transitions between regimes.

  16. Thermal analysis on the realization of the tin fixed point

    NASA Astrophysics Data System (ADS)

    Tsai, S. F.

    2013-09-01

    A study on the thermal analysis of a new tin fixed-point open cell within a new three-zone furnace was carried out. The stability at the setting temperatures of liquid-solid coexisting together with some degree Celsius lower and higher than the tin fixed point; and the axial uniformity of furnace while tin is still in solid phase were investigated and analyzed. The impurities effect on the depression in temperature was investigated in terms of ΔT (Tobserved-T1/F=0) and the inverse of the melted fraction (1/F) relationship during the melting and the following freezing realizations at various temperature settings of furnace. These thermal analysis results were also compared with those estimated by the CCT-WG1 recommended SIE (sum of individual estimates) method, which leads to a temperature correction along with a corresponding uncertainty through the individual impurity content detected by GDMS (glow discharge mass spectrometry).

  17. Fixed points, stable manifolds, weather regimes, and their predictability.

    PubMed

    Deremble, Bruno; D'Andrea, Fabio; Ghil, Michael

    2009-12-01

    In a simple, one-layer atmospheric model, we study the links between low-frequency variability and the model's fixed points in phase space. The model dynamics is characterized by the coexistence of multiple "weather regimes." To investigate the transitions from one regime to another, we focus on the identification of stable manifolds associated with fixed points. We show that these manifolds act as separatrices between regimes. We track each manifold by making use of two local predictability measures arising from the meteorological applications of nonlinear dynamics, namely, "bred vectors" and singular vectors. These results are then verified in the framework of ensemble forecasts issued from "clouds" (ensembles) of initial states. The divergence of the trajectories allows us to establish the connections between zones of low predictability, the geometry of the stable manifolds, and transitions between regimes.

  18. Fixed points, stable manifolds, weather regimes, and their predictability

    DOE PAGES

    Deremble, Bruno; D'Andrea, Fabio; Ghil, Michael

    2009-10-27

    In a simple, one-layer atmospheric model, we study the links between low-frequency variability and the model’s fixed points in phase space. The model dynamics is characterized by the coexistence of multiple ''weather regimes.'' To investigate the transitions from one regime to another, we focus on the identification of stable manifolds associated with fixed points. We show that these manifolds act as separatrices between regimes. We track each manifold by making use of two local predictability measures arising from the meteorological applications of nonlinear dynamics, namely, ''bred vectors'' and singular vectors. These results are then verified in the framework of ensemblemore » forecasts issued from clouds (ensembles) of initial states. The divergence of the trajectories allows us to establish the connections between zones of low predictability, the geometry of the stable manifolds, and transitions between regimes.« less

  19. The computational core and fixed point organization in Boolean networks

    NASA Astrophysics Data System (ADS)

    Correale, L.; Leone, M.; Pagnani, A.; Weigt, M.; Zecchina, R.

    2006-03-01

    In this paper, we analyse large random Boolean networks in terms of a constraint satisfaction problem. We first develop an algorithmic scheme which allows us to prune simple logical cascades and underdetermined variables, returning thereby the computational core of the network. Second, we apply the cavity method to analyse the number and organization of fixed points. We find in particular a phase transition between an easy and a complex regulatory phase, the latter being characterized by the existence of an exponential number of macroscopically separated fixed point clusters. The different techniques developed are reinterpreted as algorithms for the analysis of single Boolean networks, and they are applied in the analysis of and in silico experiments on the gene regulatory networks of baker's yeast (Saccharomyces cerevisiae) and the segment-polarity genes of the fruitfly Drosophila melanogaster.

  20. Fixed point structure of quenched, planar quantum electrodynamics

    SciTech Connect

    Love, S.T.

    1986-07-01

    Gauge theories exhibiting a hierarchy of fermion mass scales may contain a pseudo-Nambu-Boldstone boson of spontaneously broken scale invariance. The relation between scale and chiral symmetry breaking is studied analytically in quenched, planar quantum electrodynamics in four dimensions. The model possesses a novel nonperturbative ultraviolet fixed point governing its strong coupling phase which requires the mixing of four fermion operators. 12 refs.

  1. Assigning thermodynamic temperatures to high-temperature fixed-points

    NASA Astrophysics Data System (ADS)

    Woolliams, E. R.; Bloembergen, P.; Machin, G.

    2013-09-01

    Workpackage five of the High Temperature Fixed-Point research programme will determine the thermodynamic temperature for the equilibrium melting transition of the pure eutectic systems of Re-C, Pt-C and Co-C and, in addition, the freezing point of Cu. Measurements of four different cells of each type will be made by nine participating laboratories. This paper describes how the melt sensitivity to the rate of the previous freeze, furnace effects and cell impurities will be accounted for and how the results will be combined allowing for all existing correlations.

  2. Fate of CPN-1 fixed points with q monopoles.

    PubMed

    Block, Matthew S; Melko, Roger G; Kaul, Ribhu K

    2013-09-27

    We present an extensive quantum Monte Carlo study of the Néel to valence-bond solid (VBS) phase transition on rectangular- and honeycomb-lattice SU(N) antiferromagnets in sign-problem-free models. We find that in contrast to the honeycomb lattice and previously studied square-lattice systems, on the rectangular lattice for small N, a first-order Néel-VBS transition is realized. On increasing N≥4, we observe that the transition becomes continuous and with the same universal exponents as found on the honeycomb and square lattices (studied here for N=5, 7, 10), providing strong support for a deconfined quantum critical point. Combining our new results with previous numerical and analytical studies, we present a general phase diagram of the stability of CPN-1 fixed points with q monopoles. PMID:24116811

  3. Fixed-point error analysis of Winograd Fourier transform algorithms

    NASA Technical Reports Server (NTRS)

    Patterson, R. W.; Mcclellan, J. H.

    1978-01-01

    The quantization error introduced by the Winograd Fourier transform algorithm (WFTA) when implemented in fixed-point arithmetic is studied and compared with that of the fast Fourier transform (FFT). The effect of ordering the computational modules and the relative contributions of data quantization error and coefficient quantization error are determined. In addition, the quantization error introduced by the Good-Winograd (GW) algorithm, which uses Good's prime-factor decomposition for the discrete Fourier transform (DFT) together with Winograd's short length DFT algorithms, is studied. Error introduced by the WFTA is, in all cases, worse than that of the FFT. In general, the WFTA requires one or two more bits for data representation to give an error similar to that of the FFT. Error introduced by the GW algorithm is approximately the same as that of the FFT.

  4. Fixed Point Transformations Based Iterative Control of a Polymerization Reaction

    NASA Astrophysics Data System (ADS)

    Tar, József K.; Rudas, Imre J.

    As a paradigm of strongly coupled non-linear multi-variable dynamic systems the mathematical model of the free-radical polymerization of methyl-metachrylate with azobis (isobutyro-nitrile) as an initiator and toluene as a solvent taking place in a jacketed Continuous Stirred Tank Reactor (CSTR) is considered. In the adaptive control of this system only a single input variable is used as the control signal (the process input, i.e. dimensionless volumetric flow rate of the initiator), and a single output variable is observed (the process output, i.e. the number-average molecular weight of the polymer). Simulation examples illustrate that on the basis of a very rough and primitive model consisting of two scalar variables various fixed-point transformations based convergent iterations result in a novel, sophisticated adaptive control.

  5. Consistent Perturbative Fixed Point Calculations in QCD and Supersymmetric QCD.

    PubMed

    Ryttov, Thomas A

    2016-08-12

    We suggest how to consistently calculate the anomalous dimension γ_{*} of the ψ[over ¯]ψ operator in finite order perturbation theory at an infrared fixed point for asymptotically free theories. If the n+1 loop beta function and n loop anomalous dimension are known, then γ_{*} can be calculated exactly and fully scheme independently in a Banks-Zaks expansion through O(Δ_{f}^{n}), where Δ_{f}=N[over ¯]_{f}-N_{f}, N_{f} is the number of flavors, and N[over ¯]_{f} is the number of flavors above which asymptotic freedom is lost. For a supersymmetric theory, the calculation preserves supersymmetry order by order in Δ_{f}. We then compute γ_{*} through O(Δ_{f}^{2}) for supersymmetric QCD in the dimensional reduction scheme and find that it matches the exact known result. We find that γ_{*} is astonishingly well described in perturbation theory already at the few loops level throughout the entire conformal window. We finally compute γ_{*} through O(Δ_{f}^{3}) for QCD and a variety of other nonsupersymmetric fermionic gauge theories. Small values of γ_{*} are observed for a large range of flavors. PMID:27563948

  6. Consistent Perturbative Fixed Point Calculations in QCD and Supersymmetric QCD

    NASA Astrophysics Data System (ADS)

    Ryttov, Thomas A.

    2016-08-01

    We suggest how to consistently calculate the anomalous dimension γ* of the ψ ¯ ψ operator in finite order perturbation theory at an infrared fixed point for asymptotically free theories. If the n +1 loop beta function and n loop anomalous dimension are known, then γ* can be calculated exactly and fully scheme independently in a Banks-Zaks expansion through O (Δfn) , where Δf=N¯ f-Nf , Nf is the number of flavors, and N¯f is the number of flavors above which asymptotic freedom is lost. For a supersymmetric theory, the calculation preserves supersymmetry order by order in Δf. We then compute γ* through O (Δf2) for supersymmetric QCD in the dimensional reduction scheme and find that it matches the exact known result. We find that γ* is astonishingly well described in perturbation theory already at the few loops level throughout the entire conformal window. We finally compute γ* through O (Δf3) for QCD and a variety of other nonsupersymmetric fermionic gauge theories. Small values of γ* are observed for a large range of flavors.

  7. Comparison of three Co-C fixed points constructed using different crucible lining materials

    NASA Astrophysics Data System (ADS)

    Todd, A. D. W.; Woods, D. J.

    2013-09-01

    The melting plateaus of three Co-C fixed points for radiation thermometry with different constructions were measured and compared. Two of the fixed points were of the hybrid type and contained either carbon composite cloth or pyrolytic graphite sheet between the graphite sleeve and the crucible wall. The third fixed point contained only the graphite sleeve. Little difference was found in the shapes of the melting curves between the fixed points. Given a comparison uncertainty of 37 mK (k = 1), there were, however, significant differences in the melting temperatures determined for each of the fixed points. Over three days of measurement, the melting temperature of the fixed point filled using the pyrolytic sheet drifted up by nearly 140 mK.

  8. Existence and comparison results for fixed points of multifunctions with applications to normal-form games

    NASA Astrophysics Data System (ADS)

    Heikkila, S.

    2007-08-01

    In this paper we apply generalized iteration methods to prove comparison results which show how fixed points of a multifunction can be bounded by least and greatest fixed points of single-valued functions. As an application we prove existence and comparison results for fixed points of multifunctions. These results are applied to normal-form games, by proving existence and comparison results for pure and mixed Nash equilibria and their utilities.

  9. Copper Fixed-Point Measurements for Radiation Thermometry at National Research Council

    NASA Astrophysics Data System (ADS)

    Todd, A. D. W.; Woods, D. J.

    2014-07-01

    Due to its high transition temperature relative to other fixed points defined in the International Temperature Scale of 1990 (ITS-90) and its relatively low cost compared to silver and gold, copper is often chosen as the fixed point used to define the ITS-90 above 1235 K at national measurement institutes. Measurement of the copper freezing point can be done in a variety of furnaces. Although there are a large number of copper fixed-point designs, we expect the freezing temperatures to be the same. The difference between realizing different sized fixed points and the use of different furnaces in which to realize them is explored here. A traditional, large aperture fixed-point containing over 600 g of copper is compared to a hybrid-type fixed point containing only 15 g of copper and a commercial fixed point. Three types of furnaces including a heat-pipe furnace, a compact furnace, and a high-temperature blackbody were used to realize the copper freezing point. Between the fixed-point types, only the length of the plateau differed. However, a significant difference was found between the freezing temperatures determined in the different furnaces, and this difference was independent of cell type.

  10. Triple point of e-deuterium as an accurate thermometric fixed point

    SciTech Connect

    Pavese, F.; McConville, G.T.

    1986-01-01

    The triple point of deuterium (18.7/sup 0/K) is the only possibility for excluding vapor pressure measurements in the definition of a temperature scale based on fixed points between 13.81 and 24.562/sup 0/K. This paper reports an investigation made at the Istituto di Metrologia and Mound Laboratory, using extremely pure deuterium directly sealed at the production plant into small metal cells. The large contamination by HD of commercially available gas, that cannot be accounted and corrected for due to its increase in handling, was found to be very stable with time after sealing in IMGC cells. HD contamination can be limited to less than 100 ppM in Monsanto cells, both with n-D/sub 2/ and e-D/sub 2/, when filled directly from the thermal diffusion column and sealed at the factory. e-D/sub 2/ requires a special deuterated catalyst. The triple point temperature of e-D/sub 2/ has been determined to be: T(NPL-IPTS-68) = 18.7011 +- 0.002/sup 0/K. 20 refs., 3 figs., 2 tabs.

  11. Some fixed point theorems in generating space of b-quasi-metric family.

    PubMed

    Kumari, P Sumati; Sarwar, Muhammad

    2016-01-01

    The purpose of this work is to study some properties of "Generating space of b-quasi-metric family"(simply [Formula: see text]-family) and derive some fixed point theorems using some standard contractions. Presented theorems extend and generalize many well-known results in the literature of fixed point theory .

  12. Area law for fixed points of rapidly mixing dissipative quantum systems

    SciTech Connect

    Brandão, Fernando G. S. L.; Cubitt, Toby S.; Lucia, Angelo; Michalakis, Spyridon; Perez-Garcia, David

    2015-10-15

    We prove an area law with a logarithmic correction for the mutual information for fixed points of local dissipative quantum system satisfying a rapid mixing condition, under either of the following assumptions: the fixed point is pure or the system is frustration free.

  13. A New Co-C Eutectic Fixed-Point Cell for Thermocouple Calibration at

    NASA Astrophysics Data System (ADS)

    Failleau, G.; Deuzé, T.; Jouin, D.; Mokdad, S.; Briaudeau, S.; Sadli, M.

    2014-07-01

    The eutectic Co-C is a promising system to serve as a thermometric fixed point beyond the freezing point of copper (). Some national metrology institutes have developed, characterized, and compared their Co-C fixed-point cells based on conventional designs. Indeed, the fixed-point cells constructed are directly inspired by the technologies applied to the fixed points of the ITS-90 to the lower levels of temperature. By studying the eutectic metal-carbon systems, is appears that the high temperatures of implementation give a set of difficulties, such as the strong mechanical stresses on the graphite crucibles, due to the important thermal expansion of the eutectic alloys during their phase transitions. If these devices are suitable with research activities to serve like primary standards, it is not envisaged to propose them for a direct application to the calibration activities for the industry. As regards the limited robustness of the conventional fixed-point cells constructed, an intensive use of these device would not be reasonable, in term of cost for example. In this paper, a new Co-C fixed-point design is introduced. This low cost device has been developed specifically for intensive use in thermocouple calibration activities, with the aim of achieving the lowest level of uncertainties as is practicable. Thus, in this paper, the metrological characterization of this device is also presented, and a direct comparison to a primary Co-C fixed-point cell previously constructed is discussed.

  14. Design and Implementation of Numerical Linear Algebra Algorithms on Fixed Point DSPs

    NASA Astrophysics Data System (ADS)

    Nikolić, Zoran; Nguyen, Ha Thai; Frantz, Gene

    2007-12-01

    Numerical linear algebra algorithms use the inherent elegance of matrix formulations and are usually implemented using C/C++ floating point representation. The system implementation is faced with practical constraints because these algorithms usually need to run in real time on fixed point digital signal processors (DSPs) to reduce total hardware costs. Converting the simulation model to fixed point arithmetic and then porting it to a target DSP device is a difficult and time-consuming process. In this paper, we analyze the conversion process. We transformed selected linear algebra algorithms from floating point to fixed point arithmetic, and compared real-time requirements and performance between the fixed point DSP and floating point DSP algorithm implementations. We also introduce an advanced code optimization and an implementation by DSP-specific, fixed point C code generation. By using the techniques described in the paper, speed can be increased by a factor of up to 10 compared to floating point emulation on fixed point hardware.

  15. A fixed point theorem for certain operator valued maps

    NASA Technical Reports Server (NTRS)

    Brown, D. R.; Omalley, M. J.

    1978-01-01

    In this paper, we develop a family of Neuberger-like results to find points z epsilon H satisfying L(z)z = z and P(z) = z. This family includes Neuberger's theorem and has the additional property that most of the sequences q sub n converge to idempotent elements of B sub 1(H).

  16. Parameter Space of Fixed Points of the Damped Driven Pendulum Susceptible to Control of Chaos Algorithms

    NASA Astrophysics Data System (ADS)

    Dittmore, Andrew; Trail, Collin; Olsen, Thomas; Wiener, Richard J.

    2003-11-01

    We have previously demonstrated the experimental control of chaos in a Modified Taylor-Couette system with hourglass geometry( Richard J. Wiener et al), Phys. Rev. Lett. 83, 2340 (1999).. Identifying fixed points susceptible to algorithms for the control of chaos is key. We seek to learn about this process in the accessible numerical model of the damped, driven pendulum. Following Baker(Gregory L. Baker, Am. J. Phys. 63), 832 (1995)., we seek points susceptible to the OGY(E. Ott, C. Grebogi, and J. A. Yorke, Phys. Rev. Lett. 64), 1196 (1990). algorithm. We automate the search for fixed points that are candidates for control. We present comparisons of the space of candidate fixed points with the bifurcation diagrams and Poincare sections of the system. We demonstrate control at fixed points which do not appear on the attractor. We also show that the control algorithm may be employed to shift the system between non-communicating branches of the attractor.

  17. Implementation Considerations for Automotive Vision Systems on a Fixed-Point DSP

    NASA Astrophysics Data System (ADS)

    Nikolić, Zoran

    In this chapter we evaluate numerical requirements for implementation of camera-based lateral position detection algorithms, such as lane keep assistant (LKA) and lane departure warning (LDW) on a fixed-point DSP. We first present methods that address the challenges and requirements of fixed-point design process. The flow proposed is targeted at converting C/C++ code with floating-point operations into C code with integer operations that can then be fed through the native C compiler for a fixed-point DSP. Advanced code optimization and an implementation by DSP-specific, fixed-point C code generation are introduced. We then demonstrate the conversion flow on tracking example (extended Kalman filter) using synthetically generated data, and we analyze trade-offs for algorithm implementation in fixed-point arithmetic. By using the techniques described in this chapter speed can be increased by a factor of up to 10 compared to floating-point emulation on fixed-point hardware.

  18. Fixed point theorems for multi-valued contractive mappings and multi-valued Caristi type mappings

    NASA Astrophysics Data System (ADS)

    Feng, Yuqiang; Liu, Sanyang

    2006-05-01

    In this paper, the famous Banach contraction principle and Caristi's fixed point theorem are generalized to the case of multi-valued mappings. Our results are extensions of the well-known Nadler's fixed point theorem [S.B. Nadler Jr., Multi-valued contraction mappings, Pacific J. Math. 30 (1969) 475-487], as well as of some Caristi type theorems for multi-valued operators, see [N. Mizoguchi, W. Takahashi, Fixed point theorems for multivalued mappings on complete metric spaces, J. Math. Anal. Appl. 141 (1989) 177-188; J.P. Aubin, Optima and Equilibria. An Introduction to Nonlinear Analysis, Grad. Texts in Math., Springer-Verlag, Berlin, 1998, p. 17; S.S. Zhang, Q. Luo, Set-valued Caristi fixed point theorem and Ekeland's variational principle, Appl. Math. Mech. 10 (2) (1989) 111-113 (in Chinese), English translation: Appl. Math. Mech. (English Ed.) 10 (2) (1989) 119-121], etc.

  19. Error tolerance in an NMR implementation of Grover's fixed-point quantum search algorithm

    SciTech Connect

    Xiao Li; Jones, Jonathan A.

    2005-09-15

    We describe an implementation of Grover's fixed-point quantum search algorithm on a nuclear magnetic resonance quantum computer, searching for either one or two matching items in an unsorted database of four items. In this algorithm the target state (an equally weighted superposition of the matching states) is a fixed point of the recursive search operator, so that the algorithm always moves towards the desired state. The effects of systematic errors in the implementation are briefly explored.

  20. Conducting fixed points for inhomogeneous quantum wires: A conformally invariant boundary theory

    NASA Astrophysics Data System (ADS)

    Sedlmayr, N.; Morath, D.; Sirker, J.; Eggert, S.; Affleck, I.

    2014-01-01

    Inhomogeneities and junctions in wires are natural sources of scattering, and hence resistance. A conducting fixed point usually requires an adiabatically smooth system. One notable exception is "healing," which has been predicted in systems with special symmetries, where the system is driven to the homogeneous fixed point. Here we present theoretical results for a different type of conducting fixed point which occurs in inhomogeneous wires with an abrupt jump in hopping and interaction strength. We show that it is always possible to tune the system to an unstable conducting fixed point which does not correspond to translational invariance. We analyze the temperature scaling of correlation functions at and near this fixed point and show that two distinct boundary exponents appear, which correspond to different effective Luttinger liquid parameters. Even though the system consists of two separate interacting parts, the fixed point is described by a single conformally invariant boundary theory. We present details of the general effective bosonic field theory including the mode expansion and the finite size spectrum. The results are confirmed by numerical quantum Monte Carlo simulations on spinless fermions. We predict characteristic experimental signatures of the local density of states near junctions.

  1. Analysis of fixed point FFT for Fourier domain optical coherence tomography systems.

    PubMed

    Ali, Murtaza; Parlapalli, Renuka; Magee, David P; Dasgupta, Udayan

    2009-01-01

    Optical coherence tomography (OCT) is a new imaging modality gaining popularity in the medical community. Its application includes ophthalmology, gastroenterology, dermatology etc. As the use of OCT increases, the need for portable, low power devices also increases. Digital signal processors (DSP) are well suited to meet the signal processing requirements of such a system. These processors usually operate on fixed precision. This paper analyzes the issues that a system implementer faces implementing signal processing algorithms on fixed point processor. Specifically, we show the effect of different fixed point precisions in the implementation of FFT on the sensitivity of Fourier domain OCT systems. PMID:19965018

  2. Extending the Nonlinear-Beam-Dynamics Concept of 1D Fixed Points to 2D Fixed Lines.

    PubMed

    Franchetti, G; Schmidt, F

    2015-06-12

    The origin of nonlinear dynamics traces back to the study of the dynamics of planets with the seminal work of Poincaré at the end of the nineteenth century: Les Méthodes Nouvelles de la Mécanique Céleste, Vols. 1-3 (Gauthier Villars, Paris, 1899). In his work he introduced a methodology fruitful for investigating the dynamical properties of complex systems, which led to the so-called "Poincaré surface of section," which allows one to capture the global dynamical properties of a system, characterized by fixed points and separatrices with respect to regular and chaotic motion. For two-dimensional phase space (one degree of freedom) this approach has been extremely useful and applied to particle accelerators for controlling their beam dynamics as of the second half of the twentieth century. We describe here an extension of the concept of 1D fixed points to fixed lines in two dimensions. These structures become the fundamental entities for characterizing the nonlinear motion in the four-dimensional phase space (two degrees of freedom).

  3. Extending the Nonlinear-Beam-Dynamics Concept of 1D Fixed Points to 2D Fixed Lines

    NASA Astrophysics Data System (ADS)

    Franchetti, G.; Schmidt, F.

    2015-06-01

    The origin of nonlinear dynamics traces back to the study of the dynamics of planets with the seminal work of Poincaré at the end of the nineteenth century: Les Méthodes Nouvelles de la Mécanique Céleste, Vols. 1-3 (Gauthier Villars, Paris, 1899). In his work he introduced a methodology fruitful for investigating the dynamical properties of complex systems, which led to the so-called "Poincaré surface of section," which allows one to capture the global dynamical properties of a system, characterized by fixed points and separatrices with respect to regular and chaotic motion. For two-dimensional phase space (one degree of freedom) this approach has been extremely useful and applied to particle accelerators for controlling their beam dynamics as of the second half of the twentieth century. We describe here an extension of the concept of 1D fixed points to fixed lines in two dimensions. These structures become the fundamental entities for characterizing the nonlinear motion in the four-dimensional phase space (two degrees of freedom).

  4. Extending the Nonlinear-Beam-Dynamics Concept of 1D Fixed Points to 2D Fixed Lines.

    PubMed

    Franchetti, G; Schmidt, F

    2015-06-12

    The origin of nonlinear dynamics traces back to the study of the dynamics of planets with the seminal work of Poincaré at the end of the nineteenth century: Les Méthodes Nouvelles de la Mécanique Céleste, Vols. 1-3 (Gauthier Villars, Paris, 1899). In his work he introduced a methodology fruitful for investigating the dynamical properties of complex systems, which led to the so-called "Poincaré surface of section," which allows one to capture the global dynamical properties of a system, characterized by fixed points and separatrices with respect to regular and chaotic motion. For two-dimensional phase space (one degree of freedom) this approach has been extremely useful and applied to particle accelerators for controlling their beam dynamics as of the second half of the twentieth century. We describe here an extension of the concept of 1D fixed points to fixed lines in two dimensions. These structures become the fundamental entities for characterizing the nonlinear motion in the four-dimensional phase space (two degrees of freedom). PMID:26196806

  5. Slip instability development and earthquake nucleation as a dynamical system's fixed-point attraction

    NASA Astrophysics Data System (ADS)

    Viesca, R. C.

    2014-12-01

    A fault's transition from slow creep to the propagation of an earthquake-generating dynamic rupture is thought to start as a quasi-static slip instability. Here we examine how such an instability develops on a sliding interface whose strength is governed by a slip rate- and state-dependent friction, where the state variable evolves according to the aging law. We find that the development occurs as the attraction of a dynamical system to a fixed point. The fixed points are such that the state of slip and the rate at which velocity diverges (and its spatial distribution) are known. The fixed points are independent of the manner of external forcing and the values of slip rate and state before the onset of instability. For a fault under uniform normal stress and frictional properties, the sole parameter that determines the fixed point (to within a translational invariance) is the ratio of the frictional parameters, a/b (where, for steady-state rate weakening, 0fixed points are asymptotically stable; however, stability is lost for a/b above that value. Increasing a/b above this critical value leads to a series of Hopf bifurcations. This cascade of bifurcations signals a quasi-periodic route to chaos, implying the existence of a second, larger, critical value of a/b (corresponding to the value at which the third Hopf bifurcation occurs), above which the slip instability may develop in a chaotic fashion. The fixed-point solutions, as well as the critical thresholds concerning their stability, depend on the configuration of slip (e.g., in/anti-plane or mixed-mode slip) and the elastic environment in which the interface is embedded (e.g., a slip surface between elastic half-spaces or one lying below and parallel to a free surface); solving for a fixed point reduces to the solution of an equivalent problem of an equilibrium slip-weakening fracture; and fixed-point stability is determined by linear stability analysis. Solutions of

  6. Dark energy as a fixed point of the Einstein Yang-Mills Higgs equations

    NASA Astrophysics Data System (ADS)

    Rinaldi, Massimiliano

    2015-10-01

    We study the Einstein Yang-Mills Higgs equations in the SO(3) representation on a isotropic and homogeneous flat Universe, in the presence of radiation and matter fluids. We map the equations of motion into an autonomous dynamical system of first-order differential equations and we find the equilibrium points. We show that there is only one stable fixed point that corresponds to an accelerated expanding Universe in the future. In the past, instead, there is an unstable fixed point that implies a stiff-matter domination. In between, we find three other unstable fixed points, corresponding, in chronological order, to radiation domination, to matter domination, and, finally, to a transition from decelerated expansion to accelerated expansion. We solve the system numerically and we confirm that there are smooth trajectories that correctly describe the evolution of the Universe, from a remote past dominated by radiation to a remote future dominated by dark energy, passing through a matter-dominated phase.

  7. Side Effects in Time Discounting Procedures: Fixed Alternatives Become the Reference Point

    PubMed Central

    2016-01-01

    Typical research on intertemporal choice utilizes a two-alternative forced choice (2AFC) paradigm requiring participants to choose between a smaller sooner and larger later payoff. In the adjusting-amount procedure (AAP) one of the alternatives is fixed and the other is adjusted according to particular choices made by the participant. Such a method makes the alternatives unequal in status and is speculated to make the fixed alternative a reference point for choices, thereby affecting the decision made. The current study shows that fixing different alternatives in the AAP influences discount rates in intertemporal choices. Specifically, individuals’ (N = 283) choices were affected to just the same extent by merely fixing an alternative as when choices were preceded by scenarios explicitly imposing reference points. PMID:27768759

  8. Fixed-point bifurcation analysis in biological models using interval polynomials theory.

    PubMed

    Rigatos, Gerasimos G

    2014-06-01

    The paper proposes a systematic method for fixed-point bifurcation analysis in circadian cells and similar biological models using interval polynomials theory. The stages for performing fixed-point bifurcation analysis in such biological systems comprise (i) the computation of fixed points as functions of the bifurcation parameter and (ii) the evaluation of the type of stability for each fixed point through the computation of the eigenvalues of the Jacobian matrix that is associated with the system's nonlinear dynamics model. Stage (ii) requires the computation of the roots of the characteristic polynomial of the Jacobian matrix. This problem is nontrivial since the coefficients of the characteristic polynomial are functions of the bifurcation parameter and the latter varies within intervals. To obtain a clear view about the values of the roots of the characteristic polynomial and about the stability features they provide to the system, the use of interval polynomials theory and particularly of Kharitonov's stability theorem is proposed. In this approach, the study of the stability of a characteristic polynomial with coefficients that vary in intervals is equivalent to the study of the stability of four polynomials with crisp coefficients computed from the boundaries of the aforementioned intervals. The efficiency of the proposed approach for the analysis of fixed-point bifurcations in nonlinear models of biological neurons is tested through numerical and simulation experiments.

  9. Large- and Small-Aperture Fixed-Point Cells of Cu, Pt C, and Re C

    NASA Astrophysics Data System (ADS)

    Anhalt, Klaus; Wang, Yunfen; Yamada, Yoshiro; Hartmann, Jürgen

    2008-06-01

    Extending the application of metal (carbide) carbon eutectic fixed-point cells to radiometry, e.g., for measurements in irradiance mode, requires fixed-point cells with large apertures. In order to make large-aperture cells more readily usable in furnace systems with smaller furnace tubes commonly used for small-aperture fixed-point cells, a novel cell design was developed. For each of Cu, Pt C, and Re C fixed points, two types of fixed-point cells were manufactured, the small- and large-aperture cell. For Pt C and Re C, the large-aperture cells were filled with a hyper-eutectic metal carbon mixture; for the small cells, a hypo-eutectic mixture was used for filling. For each material, the small and large cells were compared with respect to radiometric differences. Whereas plateau shape and melting temperature are in good agreement for the small- and large-aperture Cu cells, a larger difference was observed between small- and large-aperture cells of Pt C and Re C, respectively. The origin of these observations, attributed to the temperature distribution inside the furnace, ingot contamination during manufacture, and non-uniform ingot formation for the larger cells, is discussed. The comparison of measurements by a radiation thermometer and filter radiometer of the Re C and Pt C large-aperture cells showed large differences that could be explained only by a strong radiance distribution across the cavity bottom. Further investigations are envisaged to clarify the cause.

  10. One-parameter semigroups of analytic functions, fixed points and the Koenigs function

    SciTech Connect

    Goryainov, Victor V; Kudryavtseva, Olga S

    2011-07-31

    Analogues of the Berkson-Porta formula for the infinitesimal generator of a one-parameter semigroup of holomorphic maps of the unit disc into itself are obtained in the case when, along with a Denjoy-Wolff point, there also exist other fixed points. With each one-parameter semigroup a so-called Koenigs function is associated, which is a solution, common for all elements of the one-parameter semigroup, of a certain functional equation (Schroeder's equation in the case of an interior Denjoy-Wolff point and Abel's equation in the case of a boundary Denjoy-Wolff point). A parametric representation for classes of Koenigs functions that takes account of the Denjoy-Wolff point and other fixed points of the maps in the one-parameter semigroup is presented. Bibliography: 19 titles.

  11. Existence and data dependence of fixed points for multivalued operators on gauge spaces

    NASA Astrophysics Data System (ADS)

    Espínola, Rafael; Petrusel, Adrian

    2005-09-01

    The purpose of this note is to present some fixed point and data dependence theorems in complete gauge spaces and in hyperconvex metric spaces for the so-called Meir-Keeler multivalued operators and admissible multivalued a[alpha]-contractions. Our results extend and generalize several theorems of Espínola and Kirk [R. Espínola, W.A. Kirk, Set-valued contractions and fixed points, Nonlinear Anal. 54 (2003) 485-494] and Rus, Petrusel, and Sîntamarian [I.A. Rus, A. Petrusel, A. Sîntamarian, Data dependence of the fixed point set of some multivalued weakly Picard operators, Nonlinear Anal. 52 (2003) 1947-1959].

  12. Fixed-point drift and hysteresis in frequency-scaled unimanual coordination.

    PubMed

    James, Eric G

    2012-01-01

    Research on human rhythmic coordination has shown that the in-phase and antiphase coordination modes are typically stable and that the coordination of asymmetric effectors frequently exhibits fixed-point drift. The author extended research on symmetry breaking in coordination dynamics by examining a frequency-scaled unimanual pronation-supination task. The results showed symmetry breaking and fixed-point drift, with the radioulnar joint increasingly more phase advanced than the shoulder with increments in movement frequency. Hysteresis was also observed, as the relative phase patterns produced at 3 of the 4 movement frequencies were lower in the upward frequency scaling direction than in the downward direction. These results showed that the dynamic properties of symmetry breaking and fixed-point drift in unimanual pronation-supination movements were consistent with prior research and modeling. The hysteresis effect was explained as potentially being due to the control structures that organize this redundant coordination task.

  13. Fe-C eutectic fixed-point cells for contact thermometry: an investigation and comparison

    NASA Astrophysics Data System (ADS)

    Elliott, C. J.; Pearce, J. V.; Failleau, G.; Deuzé, T.; Briaudeau, S.; Sadli, M.; Machin, G.

    2012-02-01

    Five iron-carbon (Fe-C) eutectic fixed-point cells have been constructed between NPL and LNE-Cnam to investigate the robustness and to measure the agreement of their melting temperatures. Each cell was constructed with a different selection of materials sourced by NPL and LNE-Cnam. The measured emfs at the Fe-C fixed-point temperature (~1153 °C), compared between cells, agree within around 1.98 µV (~90 mK), where the most important contribution to the uncertainty of each measurement is the inhomogeneity associated with the measuring Pt/Pd thermocouple. This demonstrates that these cells are suitable for use as secondary fixed-point cells in contact thermometry but the robustness of the presented cells is not found to be sufficient for maintaining their integrity during repeated cycling procedures.

  14. Normal form solutions of dynamical systems in the basin of attraction of their fixed points

    NASA Astrophysics Data System (ADS)

    Bountis, Tassos; Tsarouhas, George; Herman, Russell

    1998-10-01

    The normal form theory of Poincaré, Siegel and Arnol'd is applied to an analytically solvable Lotka-Volterra system in the plane, and a periodically forced, dissipative Duffing's equation with chaotic orbits in its 3-dimensional phase space. For the planar model, we determine exactly how the convergence region of normal forms about a nodal fixed point is limited by the presence of singularities of the solutions in the complex t-plane. Despite such limitations, however, we show, in the case of a periodically driven system, that normal forms can be used to obtain useful estimates of the basin of attraction of a stable fixed point of the Poincaré map, whose ``boundary'' is formed by the intersecting invariant manifolds of a second hyperbolic fixed point nearby.

  15. Miniature Fixed-Point Cell Approaches for Monitoring of Thermocouple Stability

    NASA Astrophysics Data System (ADS)

    Failleau, G.; Elliott, C. J.; Deuzé, T.; Pearce, J. V.; Machin, G.; Sadli, M.

    2014-07-01

    In the framework of the European Metrology Research Project ENG08 "MetroFission," LNE-Cnam and NPL have undertaken cooperative research into the development of temperature measurement solutions for the next generation of nuclear fission power plants. Currently, in-pile temperature monitoring is usually performed with nickel-based (Type K or N) thermocouples. When these thermocouples are exposed to a neutron flux, the thermoelements transmute, leading to large and unknown drifts in output. In addition, it is impossible to routinely recalibrate the thermocouples after irradiation for obvious reasons of safety. To alleviate this problem, both LNE-Cnam and NPL have developed, via differing approaches, in situ calibration methods for the thermocouples. The self-validating thermocouple methodologies are based on the principle of a miniature fixed-point cell to be co-located with the thermocouple measurement junction in use. The drift of the thermocouple can be monitored and corrected for by regular determination of the output at the phase transition of the fixed-point material: in effect performing regular in situ calibration checks. The two institutes have constructed miniature fixed-point cells for use at three different temperatures; the freezing point of silver ; LNE-Cnam), the freezing point of copper ; LNE-Cnam and NPL), and the melting point of Fe-C (; NPL). This paper introduces the construction and validation of the miniature fixed-point cells prior to use, to ensure traceability to the ITS-90. A comparison of the performance of the two cell designs is discussed, where typical industrial Type N thermocouples have been used for measurement of the fixed-point cells. Such initial measurements demonstrate the feasibility of each of these two approaches.

  16. Parallel fixed point implementation of a radial basis function network in an FPGA.

    PubMed

    de Souza, Alisson C D; Fernandes, Marcelo A C

    2014-01-01

    This paper proposes a parallel fixed point radial basis function (RBF) artificial neural network (ANN), implemented in a field programmable gate array (FPGA) trained online with a least mean square (LMS) algorithm. The processing time and occupied area were analyzed for various fixed point formats. The problems of precision of the ANN response for nonlinear classification using the XOR gate and interpolation using the sine function were also analyzed in a hardware implementation. The entire project was developed using the System Generator platform (Xilinx), with a Virtex-6 xc6vcx240t-1ff1156 as the target FPGA.

  17. Stability of the fixed points of the complex Swift-Hohenberg equation

    NASA Astrophysics Data System (ADS)

    Khairudin, N. I.; Abdullah, F. A.; Hassan, Y. A.

    2016-02-01

    We performed an investigation of the stability of fixed points in the complex Swift- Hohenberg equation using a variational formulation. The analysis is based on fixed points Euler-Lagrange equations and analytically showed that the Jacobian eigenvalues touched the imaginary axis and in general, Hopf bifurcation arises. The eigenvalues undergo a stability criterion in order to have Hopf's stability. Trial functions and linear loss dispersion parameter ε are responsible for the existence of stable pulse solutions in this system. We study behavior of the stable soliton-like solutions as we vary a bifurcation ε.

  18. High-Density Fixed Point for Radially Compressed Single-Component Plasmas

    SciTech Connect

    Danielson, J. R.; Surko, C. M.; O'Neil, T. M.

    2007-09-28

    Rotating electric fields are used to compress electron plasmas confined in a Penning-Malmberg trap. Bifurcation and hysteresis are observed between low-density and high-density steady states as a function of the applied electric field amplitude and frequency. These observations are explained in terms of torque-balanced fixed points using a simple model of the torques on the plasma. Perturbation experiments near the high-density fixed point are used to determine the magnitude, frequency, and voltage dependence of the drive torque. The broader implications of these results are discussed.

  19. Chiral symmetry breaking in three-dimensional quantum electrodynamics as fixed point annihilation

    NASA Astrophysics Data System (ADS)

    Herbut, Igor F.

    2016-07-01

    Spontaneous chiral symmetry breaking in three-dimensional (d =3 ) quantum electrodynamics is understood as annihilation of an infrared-stable fixed point that describes the large-N conformal phase by another unstable fixed point at a critical number of fermions N =Nc. We discuss the root of universality of Nc in this picture, together with some features of the phase boundary in the (d ,N ) plane. In particular, it is shown that as d →4 , Nc→0 with a constant slope, our best estimate of which suggests that Nc=2.89 in d =3 .

  20. Parallel Fixed Point Implementation of a Radial Basis Function Network in an FPGA

    PubMed Central

    de Souza, Alisson C. D.; Fernandes, Marcelo A. C.

    2014-01-01

    This paper proposes a parallel fixed point radial basis function (RBF) artificial neural network (ANN), implemented in a field programmable gate array (FPGA) trained online with a least mean square (LMS) algorithm. The processing time and occupied area were analyzed for various fixed point formats. The problems of precision of the ANN response for nonlinear classification using the XOR gate and interpolation using the sine function were also analyzed in a hardware implementation. The entire project was developed using the System Generator platform (Xilinx), with a Virtex-6 xc6vcx240t-1ff1156 as the target FPGA. PMID:25268918

  1. Fixed point results for G-α-contractive maps with application to boundary value problems.

    PubMed

    Hussain, Nawab; Parvaneh, Vahid; Roshan, Jamal Rezaei

    2014-01-01

    We unify the concepts of G-metric, metric-like, and b-metric to define new notion of generalized b-metric-like space and discuss its topological and structural properties. In addition, certain fixed point theorems for two classes of G-α -admissible contractive mappings in such spaces are obtained and some new fixed point results are derived in corresponding partially ordered space. Moreover, some examples and an application to the existence of a solution for the first-order periodic boundary value problem are provided here to illustrate the usability of the obtained results.

  2. Combined GPS/GLONASS precise point positioning with fixed GPS ambiguities.

    PubMed

    Pan, Lin; Cai, Changsheng; Santerre, Rock; Zhu, Jianjun

    2014-09-18

    Precise point positioning (PPP) technology is mostly implemented with an ambiguity-float solution. Its performance may be further improved by performing ambiguity-fixed resolution. Currently, the PPP integer ambiguity resolutions (IARs) are mainly based on GPS-only measurements. The integration of GPS and GLONASS can speed up the convergence and increase the accuracy of float ambiguity estimates, which contributes to enhancing the success rate and reliability of fixing ambiguities. This paper presents an approach of combined GPS/GLONASS PPP with fixed GPS ambiguities (GGPPP-FGA) in which GPS ambiguities are fixed into integers, while all GLONASS ambiguities are kept as float values. An improved minimum constellation method (MCM) is proposed to enhance the efficiency of GPS ambiguity fixing. Datasets from 20 globally distributed stations on two consecutive days are employed to investigate the performance of the GGPPP-FGA, including the positioning accuracy, convergence time and the time to first fix (TTFF). All datasets are processed for a time span of three hours in three scenarios, i.e., the GPS ambiguity-float solution, the GPS ambiguity-fixed resolution and the GGPPP-FGA resolution. The results indicate that the performance of the GPS ambiguity-fixed resolutions is significantly better than that of the GPS ambiguity-float solutions. In addition, the GGPPP-FGA improves the positioning accuracy by 38%, 25% and 44% and reduces the convergence time by 36%, 36% and 29% in the east, north and up coordinate components over the GPS-only ambiguity-fixed resolutions, respectively. Moreover, the TTFF is reduced by 27% after adding GLONASS observations. Wilcoxon rank sum tests and chi-square two-sample tests are made to examine the significance of the improvement on the positioning accuracy, convergence time and TTFF.

  3. Combined GPS/GLONASS Precise Point Positioning with Fixed GPS Ambiguities

    PubMed Central

    Pan, Lin; Cai, Changsheng; Santerre, Rock; Zhu, Jianjun

    2014-01-01

    Precise point positioning (PPP) technology is mostly implemented with an ambiguity-float solution. Its performance may be further improved by performing ambiguity-fixed resolution. Currently, the PPP integer ambiguity resolutions (IARs) are mainly based on GPS-only measurements. The integration of GPS and GLONASS can speed up the convergence and increase the accuracy of float ambiguity estimates, which contributes to enhancing the success rate and reliability of fixing ambiguities. This paper presents an approach of combined GPS/GLONASS PPP with fixed GPS ambiguities (GGPPP-FGA) in which GPS ambiguities are fixed into integers, while all GLONASS ambiguities are kept as float values. An improved minimum constellation method (MCM) is proposed to enhance the efficiency of GPS ambiguity fixing. Datasets from 20 globally distributed stations on two consecutive days are employed to investigate the performance of the GGPPP-FGA, including the positioning accuracy, convergence time and the time to first fix (TTFF). All datasets are processed for a time span of three hours in three scenarios, i.e., the GPS ambiguity-float solution, the GPS ambiguity-fixed resolution and the GGPPP-FGA resolution. The results indicate that the performance of the GPS ambiguity-fixed resolutions is significantly better than that of the GPS ambiguity-float solutions. In addition, the GGPPP-FGA improves the positioning accuracy by 38%, 25% and 44% and reduces the convergence time by 36%, 36% and 29% in the east, north and up coordinate components over the GPS-only ambiguity-fixed resolutions, respectively. Moreover, the TTFF is reduced by 27% after adding GLONASS observations. Wilcoxon rank sum tests and chi-square two-sample tests are made to examine the significance of the improvement on the positioning accuracy, convergence time and TTFF. PMID:25237901

  4. Fixed-point arithmetic for mobile devices: a fingerprinting verification case study

    NASA Astrophysics Data System (ADS)

    Moon, Yiu S.; Luk, Franklin T.; Ho, Ho C.; Tang, T. Y.; Chan, Kit C.; Leung, C. W.

    2002-12-01

    Mobile devices use embedded processors with low computing capabilities to reduce power consumption. Since floating-point arithmetic units are power hungry, computationally intensive jobs must be accomplished with either digital signal processors or hardware co-processors. In this paper, we propose to perform fixed-point arithmetic on an integer hardware unit. We illustrate the advantages of our approach by implementing fingerprint verification on mobile devices.

  5. Fixed Points of Contractive Mappings in b-Metric-Like Spaces

    PubMed Central

    Hussain, Nawab; Roshan, Jamal Rezaei

    2014-01-01

    We discuss topological structure of b-metric-like spaces and demonstrate a fundamental lemma for the convergence of sequences. As an application we prove certain fixed point results in the setup of such spaces for different types of contractive mappings. Finally, some periodic point results in b-metric-like spaces are obtained. Two examples are presented in order to verify the effectiveness and applicability of our main results. PMID:25143980

  6. Long-Term Stability of WC-C Peritectic Fixed Point

    NASA Astrophysics Data System (ADS)

    Khlevnoy, B. B.; Grigoryeva, I. A.

    2015-03-01

    The tungsten carbide-carbon peritectic (WC-C) melting transition is an attractive high-temperature fixed point with a temperature of . Earlier investigations showed high repeatability, small melting range, low sensitivity to impurities, and robustness of WC-C that makes it a prospective candidate for the highest fixed point of the temperature scale. This paper presents further study of the fixed point, namely the investigation of the long-term stability of the WC-C melting temperature. For this purpose, a new WC-C cell of the blackbody type was built using tungsten powder of 99.999 % purity. The stability of the cell was investigated during the cell aging for 50 h at the cell working temperature that tooks 140 melting/freezing cycles. The method of investigation was based on the comparison of the WC-C tested cell with a reference Re-C fixed-point cell that reduces an influence of the probable instability of a radiation thermometer. It was shown that after the aging period, the deviation of the WC-C cell melting temperature was with an uncertainty of.

  7. Intermediate fixed point in a Luttinger liquid with elastic and dissipative backscattering

    NASA Astrophysics Data System (ADS)

    Altland, Alexander; Gefen, Yuval; Rosenow, Bernd

    2015-08-01

    In a recent work [A. Altland, Y. Gefen, and B. Rosenow, Phys. Rev. Lett. 108, 136401 (2012), 10.1103/PhysRevLett.108.136401], we have addressed the problem of a Luttinger liquid with a scatterer that allows for both coherent and incoherent scattering channels. We have found that the physics associated with this model is qualitatively different from the elastic impurity setup analyzed by Kane and Fisher, and from the inelastic scattering scenario studied by Furusaki and Matveev, thus proposing a paradigmatic picture of Luttinger liquid with an impurity. Here we present an extensive study of the renormalization group flows for this problem, the fixed point landscape, and scaling near those fixed points. Our analysis is nonperturbative in the elastic tunneling amplitudes, employing an instanton calculation in one or two of the available elastic tunneling channels. Our analysis accounts for nontrivial Klein factors, which represent anyonic or fermionic statistics. These Klein factors need to be taken into account due to the fact that higher-order tunneling processes take place. In particular, we find a stable fixed point, where an incoming current is split 1/2 -1/2 between a forward and a backward scattered beams. This intermediate fixed point, between complete backscattering and full forward scattering, is stable for the Luttinger parameter g <1 .

  8. 47 CFR 90.473 - Operation of internal transmitter control systems through licensed fixed control points.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Operation of internal transmitter control... Transmitter Control Internal Transmitter Control Systems § 90.473 Operation of internal transmitter control systems through licensed fixed control points. An internal transmitter control system may be...

  9. Comparison of the copper blackbody fixed-point cavities between NIS and LNE-Cnam

    NASA Astrophysics Data System (ADS)

    Ahmed, M. G.; Ali, K.; Bourson, F.; Sadli, M.

    2013-09-01

    This paper describes the results of a bilateral comparison at the copper blackbody fixed point (1084.62 °C), one of the defining fixed points of the International Temperature Scale of 1990 in the high-temperature range. The ‘National Institute of Standards—Egypt (NIS)’ and the ‘Laboratoire Commun de Métrologie--France (LNE-Cnam)’ undertook such a comparison using an NIS linear pyrometer ‘LP4’ as a circulating radiation thermometer between the two laboratories. The main objective of this work was to compare the realizations of the copper blackbody fixed point for radiation thermometers and establish the level of agreement between the two laboratories in the high-temperature range. The comparison measurements revealed a slightly lower temperature of the NIS copper point than that of the LNE-Cnam copper point by about 0.08 °C. This difference is not significant with regard to the uncertainty and the stability of the pyrometer estimated as 0.15 °C. A second comparison was made a few months later by comparing simultaneously the two copper points at the LNE-Cnam premises. This comparison allowed determining a temperature difference of 0.045 ± 0.030 °C between the two cells, with the temperature of the LNE-Cnam cell being higher than that of NIS.

  10. Liquidus slopes of impurities in ITS-90 fixed points from the mercury point to the copper point in the low concentration limit

    NASA Astrophysics Data System (ADS)

    Pearce, Jonathan V.; Gisby, John A.; Steur, Peter P. M.

    2016-08-01

    A knowledge of the effect of impurities at the level of parts per million on the freezing temperature of very pure metals is essential for realisation of ITS-90 fixed points. New information has become available for use with the thermodynamic modelling software MTDATA, permitting calculation of liquidus slopes, in the low concentration limit, of a wider range of binary alloy systems than was previously possible. In total, calculated values for 536 binary systems are given. In addition, new experimental determinations of phase diagrams, in the low impurity concentration limit, have recently appeared. All available data have been combined to provide a comprehensive set of liquidus slopes for impurities in ITS-90 metal fixed points. In total, liquidus slopes for 838 systems are tabulated for the fixed points Hg, Ga, In, Sn, Zn, Al, Ag, Au, and Cu. It is shown that the value of the liquidus slope as a function of impurity element atomic number can be approximated using a simple formula, and good qualitative agreement with the existing data is observed for the fixed points Al, Ag, Au and Cu, but curiously the formula is not applicable to the fixed points Hg, Ga, In, Sn, and Zn. Some discussion is made concerning the influence of oxygen on the liquidus slopes, and some calculations using MTDATA are discussed. The BIPM’s consultative committee for thermometry has long recognised that the sum of individual estimates method is the ideal approach for assessing uncertainties due to impurities, but the community has been largely powerless to use the model due to lack of data. Here, not only is data provided, but a simple model is given to enable known thermophysical data to be used directly to estimate impurity effects for a large fraction of the ITS-90 fixed points.

  11. Bilateral Comparison of Mercury and Gallium Fixed-Point Cells Using Standard Platinum Resistance Thermometer

    NASA Astrophysics Data System (ADS)

    Bojkovski, J.; Veliki, T.; Zvizdić, D.; Drnovšek, J.

    2011-08-01

    The objective of project EURAMET 1127 (Bilateral comparison of triple point of mercury and melting point of gallium) in the field of thermometry is to compare realization of a triple point of mercury (-38.8344 °C) and melting point of gallium (29.7646 °C) between the Slovenian national laboratory MIRS/UL-FE/LMK and the Croatian national laboratory HMI/FSB-LPM using a long-stem 25 Ω standard platinum resistance thermometer (SPRT). MIRS/UL/FE-LMK participated in a number of intercomparisons on the level of EURAMET. On the other hand, the HMI/LPM-FSB laboratory recently acquired new fixed-point cells which had to be evaluated in the process of intercomparisons. A quartz-sheathed SPRT has been selected and calibrated at HMI/LPM-FSB at the triple point of mercury, the melting point of gallium, and the water triple point. A second set of measurements was made at MIRS/UL/FE-LMK. After its return, the SPRT was again recalibrated at HMI/LPM-FSB. In the comparison, the W value of the SPRT has been used. Results of the bilateral intercomparison confirmed that the new gallium cell of the HMI/LPM-FSB has a value that is within uncertainty limits of both laboratories that participated in the exercise, while the mercury cell experienced problems. After further research, a small leakage in the mercury fixed-point cell has been found.

  12. Searching for fixed point combinators by using automated theorem proving: A preliminary report

    SciTech Connect

    Wos, L.; McCune, W.

    1988-09-01

    In this report, we establish that the use of an automated theorem- proving program to study deep questions from mathematics and logic is indeed an excellent move. Among such problems, we focus mainly on that concerning the construction of fixed point combinators---a problem considered by logicians to be significant and difficult to solve, and often computationally intensive and arduous. To be a fixed point combinator, THETA must satisfy the equation THETAx = x(THETAx) for all combinators x. The specific questions on which we focus most heavily ask, for each chosen set of combinators, whether a fixed point combinator can be constructed from the members of that set. For answering questions of this type, we present a new, sound, and efficient method, called the kernel method, which can be applied quite easily by hand and very easily by an automated theorem-proving program. For the application of the kernel method by a theorem-proving program, we illustrate the vital role that is played by both paramodulation and demodulation---two of the powerful features frequently offered by an automated theorem-proving program for treating equality as if it is ''understood.'' We also state a conjecture that, if proved, establishes the completeness of the kernel method. From what we can ascertain, this method---which relies on the introduced concepts of kernel and superkernel---offers the first systematic approach for searching for fixed point combinators. We successfully apply the new kernel method to various sets of combinators and, for the set consisting of the combinators B and W, construct an infinite set of fixed point combinators such that no two of the combinators are equal even in the presence of extensionality---a law that asserts that two combinators are equal if they behave the same. 18 refs.

  13. Device-independent test of causal order and relations to fixed-points

    NASA Astrophysics Data System (ADS)

    Baumeler, Ämin; Wolf, Stefan

    2016-03-01

    Bell non-local correlations cannot be naturally explained in a fixed causal structure. This serves as a motivation for considering models where no global assumption is made beyond logical consistency. The assumption of a fixed causal order between a set of parties, together with free randomness, implies device-independent inequalities—just as the assumption of locality does. It is known that local validity of quantum theory is consistent with violating such inequalities. Moreover, for three parties or more, even the (stronger) assumption of local classical probability theory plus logical consistency allows for violating causal inequalities. Here, we show that a classical environment (with which the parties interact), possibly containing loops, is logically consistent if and only if whatever the involved parties do, there is exactly one fixed-point, the latter being representable as a mixture of deterministic fixed-points. We further show that the non-causal view allows for a model of computation strictly more powerful than computation in a world of fixed causal orders.

  14. Fully developed isotropic turbulence: Nonperturbative renormalization group formalism and fixed-point solution

    NASA Astrophysics Data System (ADS)

    Canet, Léonie; Delamotte, Bertrand; Wschebor, Nicolás

    2016-06-01

    We investigate the regime of fully developed homogeneous and isotropic turbulence of the Navier-Stokes (NS) equation in the presence of a stochastic forcing, using the nonperturbative (functional) renormalization group (NPRG). Within a simple approximation based on symmetries, we obtain the fixed-point solution of the NPRG flow equations that corresponds to fully developed turbulence both in d =2 and 3 dimensions. Deviations to the dimensional scalings (Kolmogorov in d =3 or Kraichnan-Batchelor in d =2 ) are found for the two-point functions. To further analyze these deviations, we derive exact flow equations in the large wave-number limit, and show that the fixed point does not entail the usual scale invariance, thereby identifying the mechanism for the emergence of intermittency within the NPRG framework. The purpose of this work is to provide a detailed basis for NPRG studies of NS turbulence; the determination of the ensuing intermittency exponents is left for future work.

  15. Fully developed isotropic turbulence: Nonperturbative renormalization group formalism and fixed-point solution.

    PubMed

    Canet, Léonie; Delamotte, Bertrand; Wschebor, Nicolás

    2016-06-01

    We investigate the regime of fully developed homogeneous and isotropic turbulence of the Navier-Stokes (NS) equation in the presence of a stochastic forcing, using the nonperturbative (functional) renormalization group (NPRG). Within a simple approximation based on symmetries, we obtain the fixed-point solution of the NPRG flow equations that corresponds to fully developed turbulence both in d=2 and 3 dimensions. Deviations to the dimensional scalings (Kolmogorov in d=3 or Kraichnan-Batchelor in d=2) are found for the two-point functions. To further analyze these deviations, we derive exact flow equations in the large wave-number limit, and show that the fixed point does not entail the usual scale invariance, thereby identifying the mechanism for the emergence of intermittency within the NPRG framework. The purpose of this work is to provide a detailed basis for NPRG studies of NS turbulence; the determination of the ensuing intermittency exponents is left for future work. PMID:27415353

  16. Many-Body Localization in One Dimension as a Dynamical Renormalization Group Fixed Point

    NASA Astrophysics Data System (ADS)

    Vosk, Ronen; Altman, Ehud

    2013-02-01

    We formulate a dynamical real space renormalization group (RG) approach to describe the time evolution of a random spin-1/2 chain, or interacting fermions, initialized in a state with fixed particle positions. Within this approach we identify a many-body localized state of the chain as a dynamical infinite randomness fixed point. Near this fixed point our method becomes asymptotically exact, allowing analytic calculation of time dependent quantities. In particular, we explain the striking universal features in the growth of the entanglement seen in recent numerical simulations: unbounded logarithmic growth delayed by a time inversely proportional to the interaction strength. This is in striking contrast to the much slower entropy growth as log⁡log⁡t found for noninteracting fermions with bond disorder. Nonetheless, even the interacting system does not thermalize in the long time limit. We attribute this to an infinite set of approximate integrals of motion revealed in the course of the RG flow, which become asymptotically exact conservation laws at the fixed point. Hence we identify the many-body localized state with an emergent generalized Gibbs ensemble.

  17. Indirect Determination of the Thermodynamic Temperature of a Gold Fixed-Point Cell

    NASA Astrophysics Data System (ADS)

    Battuello, M.; Girard, F.; Florio, M.

    2010-09-01

    Since the value T 90(Au) was fixed on the ITS-90, some determinations of the thermodynamic temperature of the gold point have been performed which form, with other renormalized results of previous measurements by radiation thermometry, the basis for the current best estimates of ( T - T 90)Au = 39.9 mK as elaborated by the CCT-WG4. Such a value, even if consistent with the behavior of T - T 90 differences at lower temperatures, is quite influenced by the low values of T Au as determined with few radiometric measurements. At INRIM, an independent indirect determination of the thermodynamic temperature of gold was performed by means of a radiation thermometry approach. A fixed-point technique was used to realize approximated thermodynamic scales from the Zn point up to the Cu point. A Si-based standard radiation thermometer working at 900 nm and 950 nm was used. The low uncertainty presently associated to the thermodynamic temperature of fixed points and the accuracy of INRIM realizations, allowed scales with an uncertainty lower than 0.03 K in terms of the thermodynamic temperature to be realized. A fixed-point cell filled with gold, 99.999 % in purity, was measured, and its freezing temperature was determined by both interpolation and extrapolation. An average T Au = 1337.395 K was found with a combined standard uncertainty of 23 mK. Such a value is 25 mK higher than the presently available value as derived by the CCT-WG4 value of ( T - T 90)Au = 39.9 mK.

  18. Bilateral Comparison Between NPL and INMETRO Using a High-Temperature Fixed Point of Unknown Temperature

    NASA Astrophysics Data System (ADS)

    Machin, G.; Teixeira, R.; Lu, X.; Lowe, D.

    2015-03-01

    There is an on-going requirement to perform scale comparisons above the silver point with reduced uncertainties. Previous comparisons have been performed with high stability lamps or radiation thermometers, neither of which were able to achieve the required uncertainty. Ideally a set of driftless unknown temperature fixed points would be used to compare scales, but up to now such artifacts did not exist. This study develops blind high-temperature comparison artifacts based on doped versions of the high-temperature fixed point (HTFP) Ni-C (nominal temperature ). At INMETRO three HTFP blackbodies were constructed, one of pure Ni-C and two doped with different levels of Cu. To ascertain the effect of doping on the transition temperature, the cells were compared to the reference pure Ni-C cell. The doped cells were then transported to NPL and their temperatures measured. NPL was not informed of the INMETRO result ensuring that the measurements remained blind. The cells were then returned to INMETRO and re-measured to establish their stability. The temperatures measured at INMETRO and NPL were then compared and showed very good equivalence of the scale at the fixed-point temperatures. The results of the comparison of the NPL and INMETRO temperature scale, at nominally , are reported, along with evidence of the stability of the artifacts determined from repeat measurements. These promising results indicate that it may be possible to make HTFPs with altered temperatures which are stable enough to serve as comparison artifacts.

  19. UV fixed-point structure of the three-dimensional Thirring model

    SciTech Connect

    Gies, Holger; Janssen, Lukas

    2010-10-15

    We investigate the UV fixed-point structure of the three-dimensional Thirring model by means of the functional renormalization group. We classify all possible 4-fermi interactions compatible with the present chiral and discrete symmetries and calculate the purely fermionic renormalization group flow using a full basis of fermionic four-point functions in the pointlike limit. Our results show that the UV complete (asymptotically safe) Thirring model lies in a two-dimensional coupling plane which reduces to the conventional Thirring coupling only in the strict large-N{sub f} limit. In addition to the Thirring universality class, which is characterized by one relevant direction (also at finite N{sub f}), two further interacting fixed points occur which may define new universality classes of second-order phase transitions also involving parity-broken phases. The N{sub f} dependence of the Thirring fixed point sheds further light on the existence of an N{sub f}-controlled quantum phase transition above which chiral symmetry remains unbroken for arbitrary large coupling, even though a definite answer will require a direct computation of competing orders.

  20. Tympanic thermometer performance validation by use of a body-temperature fixed point blackbody

    NASA Astrophysics Data System (ADS)

    Machin, Graham; Simpson, Robert

    2003-04-01

    The use of infrared tympanic thermometers within the medical community (and more generically in the public domain) has recently grown rapidly, displacing more traditional forms of thermometry such as mercury-in-glass. Besides the obvious health concerns over mercury the increase in the use of tympanic thermometers is related to a number of factors such as their speed and relatively non-invasive method of operation. The calibration and testing of such devices is covered by a number of international standards (ASTM1, prEN2, JIS3) which specify the design of calibration blackbodies. However these calibration sources are impractical for day-to-day in-situ validation purposes. In addition several studies (e.g. Modell et al4, Craig et al5) have thrown doubt on the accuracy of tympanic thermometers in clinical use. With this in mind the NPL is developing a practical, portable and robust primary reference fixed point source for tympanic thermometer validation. The aim of this simple device is to give the clinician a rapid way of validating the performance of their tympanic thermometer, enabling the detection of mal-functioning thermometers and giving confidence in the measurement to the clinician (and patient!) at point of use. The reference fixed point operates at a temperature of 36.3 °C (97.3 °F) with a repeatability of approximately +/- 20 mK. The fixed-point design has taken into consideration the optical characteristics of tympanic thermometers enabling wide-angled field of view devices to be successfully tested. The overall uncertainty of the device is estimated to be is less than 0.1°C. The paper gives a description of the fixed point, its design and construction as well as the results to date of validation tests.

  1. Experimental Investigation of the Cr3C2 C Peritectic Fixed Point

    NASA Astrophysics Data System (ADS)

    Zheng, W.; Yamada, Y.; Wang, Y.

    2008-06-01

    The Cr3C2 C (1,826°C) peritectic point was investigated for its performance as a high-temperature fixed point. Dependence on the impurity content was observed, although it was less severe for the higher of the two equilibrium temperatures obtained with the same cell, the Cr3C2 C peritectic point, than for the lower, the Cr7C3 Cr3C2 eutectic point. Thermal history had an effect on the melting plateau duration, but not on the point-of-inflection temperature nor on the melting range. The melting rate had no apparent effect. The repeatability evaluated as the standard deviation of the repeated melting plateaux within a day was 20 mK for the Cr3C2 C peritectic point, while for the Cr7C3 Cr3C2 eutectic point, this was 210 mK. For both the Cr3C2 C peritectic and the Cr7C3 Cr3C2 eutectic, the freezing plateaux often showed deep supercools, which made them unsuitable for use. The observed good repeatability shows the peritectic-point performance to be comparable to the best MC-eutectic high-temperature fixed points investigated so far. The insensitivity to thermal history constitutes an important and practical advantage. The low price of chromium is a clear benefit as compared to Pt C (1,738°C) or Ru C (1,953°C) eutectic points, the M C eutectic points in this temperature range.

  2. Comparisons between transect and fixed point in a oceanic turbulent flow: statistical analyses

    NASA Astrophysics Data System (ADS)

    Koziol, Lucie; Schmitt, Francois G.; Artigas, Felipe; Lizon, Fabrice

    2016-04-01

    Oceanological processes possess important fluctuations over large ranges of spatial and temporal scales. These fluctuations are related with the turbulence of the ocean. Usually, in turbulence, one considers fixed point Eulerian measurements, or Lagrangian measurements following an elements of fluid. On the other hand, in oceanography, measurements are often done from a boat operating over a transect, where the boat is moving in the medium at a fixed speed (relative to the flow). Here the aim of our study is to consider if such moving reference frame is modifying the statistics of the measurements. For this we compare two type of measurements at high frequency: fixed point measurements, and transect measurements, where the boat is moving at a fixed speed relative to the flow. 1 Hz fluorometer measurements are considered in both cases. Measurements have been done the same day, under similar conditions. Power spectra of time series are considered, as well as local mean and variance measurements along each transect. It is found that the spectral scaling slope of the measurement is not modified, but the variance is very different, being much larger for the moving frame. Such result needs theoretical understanding and has potential important consequence regarding the measurement that are done at high frequency on moving frames in oceanography.

  3. 2+1 flavor QCD with the fixed point action in the epsilon-regime

    NASA Astrophysics Data System (ADS)

    Hasenfratz, P.; Hierl, D.; Maillart, V.; Niedermayer, F.; Schafer, A.; Weiermann, C.; Weingart, M.

    We generated configurations with the approximate fixed-point Dirac operator $D_\\mathrm{FP}$ on a $12^4$ lattice with $a \\approx 0.13 $fm where the scale was set by $r_0$. The distributions of the low lying eigenvalues in different topological sectors were compared with those of the Random Matrix Theory which leads to a prediction of the chiral condensate.

  4. Long-Term Monitoring of Thermocouple Stability with Miniature Fixed-Point Cells

    NASA Astrophysics Data System (ADS)

    Elliott, C. J.; Failleau, G.; Deuzé, T.; Sadli, M.; Pearce, J. V.; Machin, G.

    2014-04-01

    In the framework of the European Metrology Research Programme ENG08 "MetroFission" project, two National Measurement Institutes, LNE-Cnam (France) and NPL (UK), have cooperatively developed methods of in situ validation of thermocouple output for application in next-generation nuclear fission power plants. Miniature fixed-point cells for use at three temperatures were constructed in the first step of this project: at the freezing point of silver (), the freezing point of copper (), and the melting point of the iron-carbon eutectic (). This paper reports the results of a second step in the study, where the robustness of the self-validation method has been investigated. Typical industrial Type N thermocouples have been employed with each of the miniature fixed-point devices installed, and repeatedly thermally cycled through the melting and freezing transitions of the fixed-point ingots. The devices have been exposed to a total of up to 90 h in the molten state. Furthermore, the LNE-Cnam devices were also subjected to fast cool-down rates, on five occasions, where the rate is estimated to have been between and . The devices are shown to be repeatable, reliable, and robust over the course of these tests. The drift of the Type N thermocouple has been identified separately to the behavior of the device. A reliable method for improving thermocouple performance and process control is therefore demonstrated. Requirements for implementation and the advantages of each approach for monitoring and correcting thermocouple drift are discussed, and an uncertainty budget for self-validation is presented.

  5. Fixed points of the SRG evolution and the on-shell limit of the nuclear force

    NASA Astrophysics Data System (ADS)

    Arriola, E. Ruiz; Szpigel, S.; Timóteo, V. S.

    2016-08-01

    We study the infrared limit of the similarity renormalization group (SRG) using a simple toy model for the nuclear force aiming to investigate the fixed points of the SRG evolution with both the Wilson and the Wegner generators. We show how a fully diagonal interaction at the similarity cutoff λ → 0 may be obtained from the eigenvalues of the Hamiltonian and quantify the diagonalness by means of operator norms. While the fixed points for both generators are equivalent when no bound-states are allowed by the interaction, the differences arising from the presence of the Deuteron bound-state can be disentangled very clearly by analyzing the evolved interactions in the infrared limit λ → 0 on a finite momentum grid. Another issue we investigate is the location on the diagonal of the Hamiltonian in momentum-space where the SRG evolution places the Deuteron bound-state eigenvalue once it reaches the fixed point. This finite momentum grid setup provides an alternative derivation of the celebrated trace identities, as a by product. The different effects due to either the Wilson or the Wegner generators on the binding energies of A = 2 , 3 , 4 systems are investigated and related to the occurrence of a Tjon-line which emerges as the minimum of an avoided crossing between Eα = 4Et - 3Ed and Eα = 2Et. All infrared features of the flow equations are illustrated using the toy model for the two-nucleon S-waves.

  6. Transient dynamics versus fixed points in odor representations by locust antennal lobe projection neurons.

    PubMed

    Mazor, Ofer; Laurent, Gilles

    2005-11-23

    Projection neurons (PNs) in the locust antennal lobe exhibit odor-specific dynamic responses. We studied a PN population, stimulated with five odorants and pulse durations between 0.3 and 10 s. Odor representations were characterized as time series of vectors of PN activity, constructed from the firing rates of all PNs in successive 50 ms time bins. Odor representations by the PN population can be described as trajectories in PN state space with three main phases: an on transient, lasting 1-2 s; a fixed point, stable for at least 8 s; and an off transient, lasting a few seconds as activity returns to baseline. Whereas all three phases are odor specific, optimal stimulus separation occurred during the transients rather than the fixed points. In addition, the PNs' own target neurons respond least when their PN-population input stabilized at a fixed point. Steady-state measures of activity thus seem inappropriate to understand the neural code in this system.

  7. Study on the Impurity Effect in the Realization of Silver Fixed Point

    NASA Astrophysics Data System (ADS)

    Tsai, S. F.

    2016-03-01

    The application of a thermal analysis model to estimate the temperature depression from the ideal fixed-point temperature is important, especially when the chemical analysis of the sample in a cell is insufficient or the cell might have been contaminated during fabrication. This study extends previous work, on thermal analysis with the tin point, to an investigation of the impurity dependence of the silver-point temperature. Close agreement was found between the temperature depression (-0.36 mK) inferred from the thermal analysis of the measured fixed-point plateau and the temperature depression (-0.32 mK) inferred using the sum of individual estimates (SIE) method with an impurity analysis based on glow discharge mass spectrometry. Additionally, the results of the thermal analysis manifest no significant dependence on the rate of solidification, and the scatter of observed gradients was within 0.36 mK among five plateaux with different temperature settings of the furnace. Although the results support the application of both the SIE method and thermal analysis for the silver point, further experiments with cell-to-cell comparisons linked to thermal analysis, a study of the thermometer-furnace systematic effects, the oxygen effect, and the locus of the freezing plateau should be investigated to reach a firm conclusion.

  8. Robust Optimization of Fixed Points of Nonlinear Discrete Time Systems with Uncertain Parameters

    NASA Astrophysics Data System (ADS)

    Kastsian, Darya; Monnigmann, Martin

    2010-01-01

    This contribution extends the normal vector method for the optimization of parametrically uncertain dynamical systems to a general class of nonlinear discrete time systems. Essentially, normal vectors are used to state constraints on dynamical properties of fixed points in the optimization of discrete time dynamical systems. In a typical application of the method, a technical dynamical system is optimized with respect to an economic profit function, while the normal vector constraints are used to guarantee the stability of the optimal fixed point. We derive normal vector systems for flip, fold, and Neimark-Sacker bifurcation points, because these bifurcation points constitute the stability boundary of a large class of discrete time systems. In addition, we derive normal vector systems for a related type of critical point that can be used to ensure a user-specified disturbance rejection rate in the optimization of parametrically uncertain systems. We illustrate the method by applying it to the optimization of a discrete time supply chain model and a discretized fermentation process model.

  9. SHORT COMMUNICATION: Metal carbide-carbon peritectic systems as high-temperature fixed points in thermometry

    NASA Astrophysics Data System (ADS)

    Yamada, Y.; Wang, Y.; Sasajima, N.

    2006-10-01

    WC-C, Cr3C2-C and Mn7C3-C peritectic systems were investigated for their potential of serving as high-temperature reference points in thermometry. Mixtures of high-purity graphite powder with W, Cr and Mn powder of 99.99%, 99.9% and 99.95% purity by mass, respectively, were placed in graphite blackbody crucibles and melting/freezing plateaus were observed by means of a radiation thermometer. The observed melting temperatures were 2749 °C (WC-C), 1826 °C (Cr3C2-C) and 1331 °C (Mn7C3-C), with a repeatability—in each case—of 0.02 K. The melting range for WC-C and Cr3C2-C peritectics was roughly 0.1 K. WC-C showed a flat freezing plateau that agreed with the melting plateau within the repeatability. The three fixed points are possible candidates, like the metal (carbide)-carbon eutectic fixed points, in the realization of an improved high-temperature scale above the copper point.

  10. Estimating the Contribution of Impurities to the Uncertainty of Metal Fixed-Point Temperatures

    NASA Astrophysics Data System (ADS)

    Hill, K. D.

    2014-04-01

    The estimation of the uncertainty component attributable to impurities remains a central and important topic of fixed-point research. Various methods are available for this estimation, depending on the extent of the available information. The sum of individual estimates method has considerable appeal where there is adequate knowledge of the sensitivity coefficients for each of the impurity elements and sufficiently low uncertainty regarding their concentrations. The overall maximum estimate (OME) forsakes the behavior of the individual elements by assuming that the cryoscopic constant adequately represents (or is an upper bound for) the sensitivity coefficients of the individual impurities. Validation of these methods using melting and/or freezing curves is recommended to provide confidence. Recent investigations of indium, tin, and zinc fixed points are reported. Glow discharge mass spectrometry was used to determine the impurity concentrations of the metals used to fill the cells. Melting curves were analyzed to derive an experimental overall impurity concentration (assuming that all impurities have a sensitivity coefficient equivalent to that of the cryoscopic constant). The two values (chemical and experimental) for the overall impurity concentrations were then compared. Based on the data obtained, the pragmatic approach of choosing the larger of the chemical and experimentally derived quantities as the best estimate of the influence of impurities on the temperature of the freezing point is suggested rather than relying solely on the chemical analysis and the OME method to derive the uncertainty component attributable to impurities.

  11. Uncertainty due to non-linearity in radiation thermometers calibrated by multiple fixed points

    SciTech Connect

    Yamaguchi, Y.; Yamada, Y.

    2013-09-11

    A new method to estimate the uncertainty due to non-linearity is described on the n= 3 scheme basis. The expression of uncertainty is mathematically derived applying the random walk method. The expression is simple and requires only the temperatures of the fixed points and a relative uncertainty value for each flux-doubling derived from the non-linearity measurement. We also present an example of the method, in which the uncertainty of temperature measurement by a radiation thermometer is calculated on the basis of non-linearity measurement.

  12. Standard map in magnetized relativistic systems: fixed points and regular acceleration.

    PubMed

    de Sousa, M C; Steffens, F M; Pakter, R; Rizzato, F B

    2010-08-01

    We investigate the concept of a standard map for the interaction of relativistic particles and electrostatic waves of arbitrary amplitudes, under the action of external magnetic fields. The map is adequate for physical settings where waves and particles interact impulsively, and allows for a series of analytical result to be exactly obtained. Unlike the traditional form of the standard map, the present map is nonlinear in the wave amplitude and displays a series of peculiar properties. Among these properties we discuss the relation involving fixed points of the maps and accelerator regimes.

  13. Unitarity violation at the Wilson-Fisher fixed point in 4 -ɛ dimensions

    NASA Astrophysics Data System (ADS)

    Hogervorst, Matthijs; Rychkov, Slava; van Rees, Balt C.

    2016-06-01

    We consider the continuation of free and interacting scalar field theory to noninteger spacetime dimension d . We find that the correlation functions in these theories are necessarily incompatible with unitarity (or with reflection positivity in Euclidean signature). In particular, the theories contain negative-norm states unless d is a positive integer. These negative-norm states can be obtained via the operator product expansion from simple positive-norm operators, and are therefore an integral part of the theory. At the Wilson-Fisher fixed point the nonunitarity leads to the existence of complex anomalous dimensions. We demonstrate that they appear already at leading order in the epsilon expansion.

  14. New Sealed Cells for Realization of Cryogenic Fixed Points at NMIJ/AIST

    NASA Astrophysics Data System (ADS)

    Nakano, Tohru; Tamura, Osamu; Sakurai, Hirohisa

    2003-09-01

    New sealed cells have been developed at the National Metrology Institute of Japan (NMIJ), which are used for realization of the cryogenic fixed points of the International Temperature Scale of 1990. A metal O-ring made of stainless steel is introduced as a sealing device for the sealed cells. The triple point of equilibrium hydrogen (e-H2) is realized using the new sealed cells containing hydrogen and ferric oxy-hydroxide as a catalyst for the ortho-para equilibration. Double anomalous peaks on the heat capacity curves are observed at temperatures just below the triple point, but they are suppressed by reducing the amount of the catalyst. The reduction of the amount of catalyst allows one to obtain more reliable melting curves for e-H2. The triple-point temperature of e-H2 obtained by the new sealed cells is in good agreement with those reported previously in measurements of open cells by assuming that the dependence of the triple-point temperature on the deuterium content is 5.4 μK per ppm of deuterium in hydrogen.

  15. Development of a new radiometer for the thermodynamic measurement of high temperature fixed points

    SciTech Connect

    Dury, M. R.; Goodman, T. M.; Lowe, D. H.; Machin, G.; Woolliams, E. R.

    2013-09-11

    The National Physical Laboratory (NPL) has developed a new radiometer to measure the thermodynamic melting point temperatures of high temperature fixed points with ultra-low uncertainties. In comparison with the NPL's Absolute Radiation Thermometer (ART), the 'THermodynamic Optical Radiometer' (THOR) is more portable and compact, with a much lower size-of-source effect and improved performance in other parameters such as temperature sensitivity. It has been designed for calibration as a whole instrument via the radiance method, removing the need to calibrate the individual subcomponents, as required by ART, and thereby reducing uncertainties. In addition, the calibration approach has been improved through a new integrating sphere that has been designed to have greater uniformity.

  16. Influence of Impurities and Filling Protocol on the Aluminum Fixed Point

    NASA Astrophysics Data System (ADS)

    Renaot, E.; Valin, M. H.; Elgourdou, M.

    2008-06-01

    To improve the uncertainty of the aluminum fixed point, a study was launched by LNE-INM/CNAM in the framework of the EUROMET Project 732 “Toward more accurate temperature fixed points” (Coordinating laboratory: LNE-INM/CNAM, 17 partner countries). A new open cell was filled with aluminum of 99.99995% purity. A French laboratory carried out elemental analysis of the sample using glow discharge-mass spectrometry (GD-MS). The values of the equilibrium distribution coefficient k and of the derivative {δ T_{{l}}/δ ci_{{l}}} of the temperature of the liquidus line with respect to the concentration of impurity i will be obtained through collaboration with a French physical and chemical laboratory. In the past, some aluminum cells were opened after several melts and freezes. The aluminum ingot was sticking to the graphite crucible, indicating that physicochemical reactions had likely occurred between Al and C. To avoid this reaction, an effort was made to draw benefit from the Al2O3 film that appears immediately on the surface of the aluminum ingot when it is exposed to oxygen. The open aluminum cell was tested in different furnaces and with different thermal insulator arrangements inside the fixed-point assembly. The observed drifts of the plateaux were always larger than the expected values. The cell was opened to inspect the aluminum ingot. The ingot was extracted easily, since no sticking to the crucible had occurred. The aluminum showed a very bright surface, but the presence of many “craters” throughout the thickness of the ingot was surprising. In some cases, the thermometer well was even apparent.

  17. Investigation of TiC C Eutectic and WC C Peritectic High-Temperature Fixed Points

    NASA Astrophysics Data System (ADS)

    Sasajima, Naohiko; Yamada, Yoshiro

    2008-06-01

    TiC C eutectic (2,761°C) and WC C peritectic (2,749°C) fixed points were investigated to compare their potential as high-temperature thermometric reference points. Two TiC C and three WC C fixed-point cells were constructed, and the melting and freezing plateaux were evaluated by means of radiation thermometry. The repeatability of the TiC C eutectic within a day was 60 mK with a melting range roughly 200 mK. The repeatability of the melting temperature of the WC C peritectic within 1 day was 17 mK with a melting range of ˜70 mK. The repeatability of the freezing temperature of the WC C peritectic was 21 mK with a freezing range less than 20 mK. One of the TiC C cells was constructed from a TiC and graphite powder mixture. The filling showed the reaction with the graphite crucible was suppressed and the ingot contained less voids, although the lack of high-purity TiC powder poses a problem. The WC C cells were easily constructed, like metal carbon eutectic cells, without any evident reaction with the crucible. From these results, it is concluded that the WC C peritectic has more potential than the TiC C eutectic as a high-temperature reference point. The investigation of the purification of the TiC C cell during filling and the plateau observation are also reported.

  18. Optimization of the thermogauge furnace for realizing high temperature fixed points

    SciTech Connect

    Wang, T.; Dong, W.; Liu, F.

    2013-09-11

    The thermogauge furnace was commonly used in many NMIs as a blackbody source for calibration of the radiation thermometer. It can also be used for realizing the high temperature fixed point(HTFP). According to our experience, when realizing HTFP we need the furnace provide relative good temperature uniformity to avoid the possible damage to the HTFP. To improve temperature uniformity in the furnace, the furnace tube was machined near the tube ends with a help of a simulation analysis by 'ansys workbench'. Temperature distributions before and after optimization were measured and compared at 1300 °C, 1700°C, 2500 °C, which roughly correspond to Co-C(1324 °C), Pt-C(1738 °C) and Re-C(2474 °C), respectively. The results clearly indicate that through machining the tube the temperature uniformity of the Thermogage furnace can be remarkably improved. A Pt-C high temperature fixed point was realized in the modified Thermogauge furnace subsequently, the plateaus were compared with what obtained using old heater, and the results were presented in this paper.

  19. Stability of cobalt-carbon high temperature fixed points doped with iron and platinum

    NASA Astrophysics Data System (ADS)

    Kňazovická, L.; Lowe, D.; Machin, G.; Davies, H.; Rani, A.

    2015-04-01

    High temperature fixed points (HTFPs) are stable and repeatable and make comparison of temperature scales possible at a level of uncertainty not previously possible. However, they potentially lack objectivity if the fixed-point temperature is known. Five HTFPs were constructed, one pure Co-C, two Co-C doped with Fe and two Co-C doped with Pt of differing concentrations. The candidate dopants were identified through thermochemical modelling as likely to give maximum temperature shift with minimum increase in melting range. The temperature differences of the doped systems from the pure system were determined and it was found that the addition of Fe depressed the melting temperature and the addition of Pt elevated the melting temperature, qualitatively in line with the thermochemical modelling. The higher concentration doped HTFPs were then aged for approximately 100 h with continuous melting-freezing cycles and the difference to the undoped Co-C HTFP remeasured. These differences were found to agree with those of the unaged results within the measurement uncertainties, confirming artefact stability. It is clear that the doping of HTFPs is a powerful way of constructing stable and reliable high temperature scale comparison artefacts of unknown temperature.

  20. Use of Eutectic Fixed Points to Characterize a Spectrometer for Earth Observations

    NASA Astrophysics Data System (ADS)

    Salim, Saber G. R.; Fox, Nigel P.; Woolliams, Emma R.; Winkler, Rainer; Pegrum, Heather M.; Sun, Tong; Grattan, Ken T. V.

    2007-12-01

    A small palm-sized, reference spectrometer, mounted on a remote-controlled model helicopter is being developed and tested by the National Physical Laboratory (NPL) in conjunction with City University, London. The developed system will be used as a key element for field vicarious calibration of optical earth observation systems in the visible-near infrared (VNIR) region. The spectrometer is hand held, low weight, and uses a photodiode array. It has good stray light rejection and wide spectral coverage, allowing simultaneous measurements from 400 to 900 nm. The spectrometer is traceable to NPL’s primary standard cryogenic radiometer via a high-temperature metal-carbon eutectic fixed-point blackbody. Once the fixed-point temperature has been determined (using filter radiometry), the eutectic provides a high emissivity and high stability source of known spectral radiance over the emitted spectral range. All wavelength channels of the spectrometer can be calibrated simultaneously using the eutectic transition without the need for additional instrumentation. The spectrometer itself has been characterized for stray light performance and wavelength accuracy. Its long-term and transportation stability has been proven in an experiment that determined the “World’s Bluest Sky”—a process that involved 56 flights, covering 100,000 km in 72 days. This vicarious calibration methodology using a eutectic standard is presented alongside the preliminary results of an evaluation study of the spectrometer characteristics.

  1. Investigation of Furnace Uniformity and its Effect on High-Temperature Fixed-Point Performance

    NASA Astrophysics Data System (ADS)

    Khlevnoy, B.; Sakharov, M.; Ogarev, S.; Sapritsky, V.; Yamada, Y.; Anhalt, K.

    2008-02-01

    A large-area furnace BB3500YY was designed and built at the VNIIOFI as a furnace for high-temperature metal (carbide)-carbon (M(C)-C) eutectic fixed points and was then investigated at the NMIJ. The dependence of the temperature uniformity of the furnace on various heater and cell holder arrangements was investigated. After making some improvements, the temperature of the central part of the furnace was uniform to within 2K over a length of 40 mm—the length of the fixed-point cell—at a temperature of 2,500°C. With this furnace, the melting plateaux of Re-C and TiC-C were shown to be better than those observed in other furnaces. For instance, a Re-C cell showed melting plateaux with a 0.1K melting range and a duration of about 40 min. Furthermore, to verify the capability of the furnace to fill cells, one Re-C and one TiC-C cell were made using the BB3500YY. The cells were then compared to a Re-C cell made in a Nagano furnace and a TiC-C cell filled in a BB3200pg furnace. The agreement in plateau shapes demonstrates the capability of the BB3500YY furnace to also function as a filling furnace.

  2. Acoustic resonator providing fixed points of temperature between 0.1 and 2 K

    NASA Astrophysics Data System (ADS)

    Salmela, Anssi; Tuoriniemi, Juha; Pentti, Elias; Sebedash, Alexander; Rysti, Juho

    2009-02-01

    Below 2 K the speed of second sound in mixtures of liquid 3He and 4He first increases to a maximum of 30-40 m/s at about 1 K and then decreases again at lower temperatures to values below 15 m/s. The exact values depend on the concentration and pressure of the mixture. This can be exploited to provide fixed points in temperature by utilizing a resonator with appropriate dimensions and frequency to excite standing waves in the resonator cavity filled with helium mixture. We demonstrate that commercially mass produced quartz tuning forks can be used for this purpose. They are meant for frequency standards operating at 32 kHz. Their dimensions are typically of order 1 mm matching the wavelength of the second sound in helium mixtures at certain values of temperature. Due to the complicated geometry, we observe some 20 sharp acoustic resonances in the range 0.1ell 2 K having temperature resolution of order 1 μK. The quartz resonators are cheap, compact, simple to implement, easy to measure with great accuracy, and, above all, they are not sensitive to magnetic field, which is a great advantage compared to fixed point devices based on superconductivity transitions. The reproducibility of the resonance pattern upon thermal cycling remains to be verified.

  3. Dipeptide Aggregation in Aqueous Solution from Fixed Point-Charge Force Fields.

    PubMed

    Götz, Andreas W; Bucher, Denis; Lindert, Steffen; McCammon, J Andrew

    2014-04-01

    The description of aggregation processes with molecular dynamics simulations is a playground for testing biomolecular force fields, including a new generation of force fields that explicitly describe electronic polarization. In this work, we study a system consisting of 50 glycyl-l-alanine (Gly-Ala) dipeptides in solution with 1001 water molecules. Neutron diffraction experiments have shown that at this concentration, Gly-Ala aggregates into large clusters. However, general-purpose force fields in combination with established water models can fail to correctly describe this aggregation process, highlighting important deficiencies in how solute-solute and solute-solvent interactions are parametrized in these force fields. We found that even for the fully polarizable AMOEBA force field, the degree of association is considerably underestimated. Instead, a fixed point-charge approach based on the newly developed IPolQ scheme [Cerutti et al. J. Phys. Chem.2013, 117, 2328] allows for the correct modeling of the dipeptide aggregation in aqueous solution. This result should stimulate interest in novel fitting schemes that aim to improve the description of the solvent polarization effect within both explicitly polarizable and fixed point-charge frameworks.

  4. An optimized treatment for algorithmic differentiation of an important glaciological fixed-point problem

    NASA Astrophysics Data System (ADS)

    Goldberg, Daniel N.; Krishna Narayanan, Sri Hari; Hascoet, Laurent; Utke, Jean

    2016-05-01

    We apply an optimized method to the adjoint generation of a time-evolving land ice model through algorithmic differentiation (AD). The optimization involves a special treatment of the fixed-point iteration required to solve the nonlinear stress balance, which differs from a straightforward application of AD software, and leads to smaller memory requirements and in some cases shorter computation times of the adjoint. The optimization is done via implementation of the algorithm of Christianson (1994) for reverse accumulation of fixed-point problems, with the AD tool OpenAD. For test problems, the optimized adjoint is shown to have far lower memory requirements, potentially enabling larger problem sizes on memory-limited machines. In the case of the land ice model, implementation of the algorithm allows further optimization by having the adjoint model solve a sequence of linear systems with identical (as opposed to varying) matrices, greatly improving performance. The methods introduced here will be of value to other efforts applying AD tools to ice models, particularly ones which solve a hybrid shallow ice/shallow shelf approximation to the Stokes equations.

  5. Temperature determination of the Si-SiC eutectic fixed point using thermocouples

    NASA Astrophysics Data System (ADS)

    Suherlan; Kim, Yong-Gyoo; Joung, Wukchul; Yang, Inseok

    2015-04-01

    The temperature of the Si-SiC eutectic fixed point for use in thermocouple thermometry has been determined. Three Si-SiC cells were fabricated from pure silicon powder within separate graphite crucibles. Each of the three cells was cycled through 17 melt-freeze cycles and subjected to temperatures above 1400 °C for a period of approximately 73 h, and none showed any sign of mechanical failure. The melting transition was measured using three types of thermocouple: one type S, one type B, and two Pt/Pd thermocouples calibrated at the fixed points of Ag, Cu, Fe-C, Co-C, and Pd (only for type B). The transition temperature, measured using the type S and two Pt/Pd thermocouples, was (1410.0 ± 0.8) °C with k = 2. However, the measurement uncertainty using the type B thermocouple was as large as 1.5 °C (k = 2) due to the inhomogeneity of the thermocouple. The repeatability of the three Si-SiC cells was calculated to be 0.3 °C, and the extremes of the temperature measurement differed by 0.8 °C.

  6. Stability of a cubic fixed point in three dimensions: Critical exponents for generic N

    NASA Astrophysics Data System (ADS)

    Varnashev, K. B.

    2000-06-01

    The detailed analysis of the global structure of the renormalization-group (RG) flow diagram for a model with isotropic and cubic interactions is carried out in the framework of the massive field theory directly in three dimensions (3D) within an assumption of isotropic exchange. Perturbative expansions for RG functions are calculated for arbitrary N up to four-loop order and resummed by means of the generalized Padé-Borel-Leroy technique. Coordinates and stability matrix eigenvalues for the cubic fixed point are found under the optimal value of the transformation parameter. Critical dimensionality of the model is proved to be equal to Nc=2.89+/-0.02 that agrees well with the estimate obtained on the basis of the five-loop ɛ expansion [H. Kleinert and V. Schulte-Frohlinde, Phys. Lett. B 342, 284 (1995)] resummed by the above method. As a consequence, the cubic fixed point should be stable in 3D for N>=3, and the critical exponents controlling phase transitions in three-dimensional magnets should belong to the cubic universality class. The critical behavior of the random Ising model being the nontrivial particular case of the cubic model when N=0 is also investigated. For all physical quantities of interest the most accurate numerical estimates with their error bounds are obtained. The results achieved in the work are discussed along with the predictions given by other theoretical approaches and experimental data.

  7. Thermodynamic temperature assignment to the point of inflection of the melting curve of high-temperature fixed points.

    PubMed

    Woolliams, E R; Anhalt, K; Ballico, M; Bloembergen, P; Bourson, F; Briaudeau, S; Campos, J; Cox, M G; del Campo, D; Dong, W; Dury, M R; Gavrilov, V; Grigoryeva, I; Hernanz, M L; Jahan, F; Khlevnoy, B; Khromchenko, V; Lowe, D H; Lu, X; Machin, G; Mantilla, J M; Martin, M J; McEvoy, H C; Rougié, B; Sadli, M; Salim, S G R; Sasajima, N; Taubert, D R; Todd, A D W; Van den Bossche, R; van der Ham, E; Wang, T; Whittam, A; Wilthan, B; Woods, D J; Woodward, J T; Yamada, Y; Yamaguchi, Y; Yoon, H W; Yuan, Z

    2016-03-28

    The thermodynamic temperature of the point of inflection of the melting transition of Re-C, Pt-C and Co-C eutectics has been determined to be 2747.84 ± 0.35 K, 2011.43 ± 0.18 K and 1597.39 ± 0.13 K, respectively, and the thermodynamic temperature of the freezing transition of Cu has been determined to be 1357.80 ± 0.08 K, where the ± symbol represents 95% coverage. These results are the best consensus estimates obtained from measurements made using various spectroradiometric primary thermometry techniques by nine different national metrology institutes. The good agreement between the institutes suggests that spectroradiometric thermometry techniques are sufficiently mature (at least in those institutes) to allow the direct realization of thermodynamic temperature above 1234 K (rather than the use of a temperature scale) and that metal-carbon eutectics can be used as high-temperature fixed points for thermodynamic temperature dissemination. The results directly support the developing mise en pratique for the definition of the kelvin to include direct measurement of thermodynamic temperature.

  8. Thermodynamic temperature assignment to the point of inflection of the melting curve of high-temperature fixed points.

    PubMed

    Woolliams, E R; Anhalt, K; Ballico, M; Bloembergen, P; Bourson, F; Briaudeau, S; Campos, J; Cox, M G; del Campo, D; Dong, W; Dury, M R; Gavrilov, V; Grigoryeva, I; Hernanz, M L; Jahan, F; Khlevnoy, B; Khromchenko, V; Lowe, D H; Lu, X; Machin, G; Mantilla, J M; Martin, M J; McEvoy, H C; Rougié, B; Sadli, M; Salim, S G R; Sasajima, N; Taubert, D R; Todd, A D W; Van den Bossche, R; van der Ham, E; Wang, T; Whittam, A; Wilthan, B; Woods, D J; Woodward, J T; Yamada, Y; Yamaguchi, Y; Yoon, H W; Yuan, Z

    2016-03-28

    The thermodynamic temperature of the point of inflection of the melting transition of Re-C, Pt-C and Co-C eutectics has been determined to be 2747.84 ± 0.35 K, 2011.43 ± 0.18 K and 1597.39 ± 0.13 K, respectively, and the thermodynamic temperature of the freezing transition of Cu has been determined to be 1357.80 ± 0.08 K, where the ± symbol represents 95% coverage. These results are the best consensus estimates obtained from measurements made using various spectroradiometric primary thermometry techniques by nine different national metrology institutes. The good agreement between the institutes suggests that spectroradiometric thermometry techniques are sufficiently mature (at least in those institutes) to allow the direct realization of thermodynamic temperature above 1234 K (rather than the use of a temperature scale) and that metal-carbon eutectics can be used as high-temperature fixed points for thermodynamic temperature dissemination. The results directly support the developing mise en pratique for the definition of the kelvin to include direct measurement of thermodynamic temperature. PMID:26903099

  9. A Comparison of Visual Fields with Fixed and Moving Fixation Points. Volume I

    NASA Astrophysics Data System (ADS)

    McLean, William E.

    2002-09-01

    Four procedures were used to measure the extent of the detection fields of four primary meridians of the binocular visual fields of four subjects. Procedure I (Moving Target) used a horizontally moving target and a stationary fixation point. Procedure II (Fixed Target) used a stationary target and a horizontally moving fixation point. Procedure III (Saccadic Move) used a saccadic eye movement between two stationary horizontal fixation points and a stationary target. Procedure IV (Flashed Target) used a stationary fixation point and a .6 second flashed target. The results from the dynamic procedures (I and II) and the two static procedures (III and IV) were very similar for each subject. In the dynamic procedures, the relationship between a change in contrast and an equivalent change in velocity tends to support Bloch's Law (IxT=C) between 2 deg/s and 20 deg/s for a given retinal location. The relationship between the reciprocal of relative single glimpse probability of four subjects measured in this study and the mean detection times for comparable stimuli taken from Krendel and Wodinsky's study (1960) appear to be linear and highly correlated (.92 to .99). Volume I of this report details the technical report and volume II contains the appendices.

  10. The European Fixed point Open Ocean Observatory network (FixO3): Multidisciplinary observations from the air-sea interface to the deep seafloor

    NASA Astrophysics Data System (ADS)

    Lampitt, Richard; Cristini, Luisa; Alexiou, Sofia

    2015-04-01

    The Fixed point Open Ocean Observatory network (FixO3, http://www.fixo3.eu/ ) integrates 23 European open ocean fixed point observatories and improves access to these infrastructures for the broader community. These provide multidisciplinary observations in all parts of the oceans from the air-sea interface to the deep seafloor. Started in September 2013 with a budget of 7 Million Euros over 4 years, the project has 29 partners drawn from academia, research institutions and SME's coordinated by the National Oceanography Centre, UK. Here we present the programme's achievements in the 18 months and the activities of the 12 Work Packages which have the objectives to: • integrate and harmonise the current procedures and processes • offer free access to observatory infrastructures to those who do not have such access, and free and open data services and products • innovate and enhance the current capability for multidisciplinary in situ ocean observation Open ocean observation is a high priority for European marine and maritime activities. FixO3 provides important data and services to address the Marine Strategy Framework Directive and in support of the European Integrated Maritime Policy. FixO3 provides a strong integrated framework of open ocean facilities in the Atlantic from the Arctic to the Antarctic and throughout the Mediterranean, enabling an integrated, regional and multidisciplinary approach to understand natural and anthropogenic change in the ocean.

  11. New Filling Technique and Performance Evaluations of the Cr3C2-C Peritectic Fixed Point

    NASA Astrophysics Data System (ADS)

    Sasajima, N.; Lowe, D.; Bai, C.; Yamada, Y.; Ara, C.

    2011-12-01

    The Cr3C2-C peritectic fixed point was investigated to test its capability to serve as a practical high-temperature fixed point. An improved filling technique where C/C sheet works as a wick and graphite paper as a hopper was applied successfully, and the long-term stability of the peritectic cell was evaluated by means of radiation thermometry. The repeatability of the melting point in one day was 7 mK with a melting range of approximately 100 mK. The cell was aged for 7 days, and the evaluated 56 melting temperatures during this period all fall within 90 mK, with a standard deviation of 19 mK. X-ray transmission photos showed that the ingot was filled uniformly in the crucible. After the evaluation of long-term stability, no clear degradation of the ingot shape and no leakage of molten metal were observed. From these results, it can be concluded that the Cr3C2-C peritectic cell has good stability and robustness, and the new filling technique was established. The impurity effect on the Cr3C2-C peritectic cell was also investigated by adding tungsten powder to another cell as the impurity component. After the observation of melting and freezing plateaux, the cell was cut in half to analyze the microstructure by means of electron probe microanalysis (EPMA) and laser ablation inductively coupled plasma mass spectrometer (LA-ICP-MS). The high concentration of impurity was observed in the area of the chromium-rich domain (eutectic mixture of Cr7C3 and Cr3C2), which suggests that impurities were rejected from the Cr3C2 peritectic phase during the peritectic freezing and were accumulated in the Cr7C3-Cr3C2 eutectic phase. This explains why the impurity effect is more severe for the Cr7C3-Cr3C2 eutectic point than for the Cr3C2-C peritectic point.

  12. Hybrid algorithm for common solution of monotone inclusion problem and fixed point problem and applications to variational inequalities.

    PubMed

    Zhang, Jingling; Jiang, Nan

    2016-01-01

    The aim of this paper is to investigate hybrid algorithm for a common zero point of the sum of two monotone operators which is also a fixed point of a family of countable quasi-nonexpansive mappings. We point out two incorrect proof in paper (Hecai in Fixed Point Theory Appl 2013:11, 2013). Further, we modify and generalize the results of Hecai's paper, in which only a quasi-nonexpansive mapping was considered. In addition, two family of countable quasi-nonexpansive mappings with uniform closeness examples are provided to demonstrate our results. Finally, the results are applied to variational inequalities.

  13. Crustal deformation measurements in central Japan determined by a Global Positioning System fixed-point network

    NASA Technical Reports Server (NTRS)

    Shimada, Seiichi; Bock, Yehuda

    1992-01-01

    Results are presented from temporally dense measurements of crustal deformation associated with the convergence of the Eurasian (EUR), Pacific, North American, and Philippine Sea (PHS) plates, carried out in April 1988 by a 10-station GPS fixed-point network established in central Japan. Using regional orbit relaxation methods, the analysis of the first 17-month data revealed significant horizontal deformation across the Suruga trough. Namely, it was found that a site in the northern tip of PHS plate moved nearly westward with a velocity of 28 +/-5 mm per year, and a site at the southeastern tip of EUR plate moved south-southwestward with a velocity of 18 +/-5 mm per year. A significant vertical uplift with a velocity of 20 mm/yr was detected at a site inland of the Tokai district located in the Akaishi uplift zone and at a site on the Hatsushima Island in Sagami Bay.

  14. Investigation of Fixed Points Exceeding 2500 °C Using Metal Carbide-Carbon Eutectics

    NASA Astrophysics Data System (ADS)

    Sasajima, N.; Yamada, Y.; Sakuma, F.

    2003-09-01

    The melting and freezing plateaus of four metal carbide-carbon (MC-C) eutectics, B4C-C, δ(Mo carbide)-C, TiC-C and ZrC-C eutectics were investigated by radiation thermometry for the first time. The observed melting temperatures were 2386 °C, 2583 °C, 2761 °C and 2883 °C, respectively. The plateau shapes of δ(Mo carbide)-C, TiC-C and ZrC-C eutectics are relatively flat compared to the quite rounded plateau shape of the B4C-C eutectic. The results indicate that MC-C eutectics can establish a new series of high-temperature fixed points above 2500 °C.

  15. Point and Fixed Plot Sampling Inventory Estimates at the Savannah River Site, South Carolina.

    SciTech Connect

    Parresol, Bernard, R.

    2004-02-01

    This report provides calculation of systematic point sampling volume estimates for trees greater than or equal to 5 inches diameter breast height (dbh) and fixed radius plot volume estimates for trees < 5 inches dbh at the Savannah River Site (SRS), Aiken County, South Carolina. The inventory of 622 plots was started in March 1999 and completed in January 2002 (Figure 1). Estimates are given in cubic foot volume. The analyses are presented in a series of Tables and Figures. In addition, a preliminary analysis of fuel levels on the SRS is given, based on depth measurements of the duff and litter layers on the 622 inventory plots plus line transect samples of down coarse woody material. Potential standing live fuels are also included. The fuels analyses are presented in a series of tables.

  16. Density equalized map projections: a method for analysing clustering around a fixed point.

    PubMed

    Schulman, J; Selvin, S; Merrill, D W

    1988-04-01

    Cases plotted on a geopolitical map entail difficulties in interpretation and analysis because of variable population density in the study area. Density equalized map projections (DEMPs) eliminate the distribution of the resident population as an interfering influence by transforming map area to be proportional to population. This paper discusses a transformation algorithm, its properties, and develops statistical methods to detect clustering of cases around a fixed point for data plotted on DEMPs. We suggest two numeric methods where exact solutions are too complicated or do not exist. Finally, we illustrate these methods using data from Denver and Jefferson counties in Colorado to investigate whether lung cancer and leukaemia incidence patterns are associated with plutonium exposure from the Rocky Flats plant site. PMID:3368676

  17. Progress report for the CCT-WG5 high temperature fixed point research plan

    SciTech Connect

    Machin, G.; Woolliams, E. R.; Anhalt, K.; Bloembergen, P.; Sadli, M.; Yamada, Y.

    2013-09-11

    An overview of the progress in High Temperature Fixed Point (HTFP) research conducted under the auspices of the CCT-WG5 research plan is reported. In brief highlights are: Provisional long term stability of HTFPs has been demonstrated. Optimum construction methods for HTFPs have been established and high quality HTFPs of Co-C, Pt-C and Re-C have been constructed for thermodynamic temperature assignment. The major sources of uncertainty in the assignment of thermodynamic temperature have been identified and quantified. The status of absolute radiometric temperature measurement has been quantified through the circulation of a set of HTFPs. The measurement campaign to assign low uncertainty thermodynamic temperatures to a selected set of HTFPs will begin in mid-2012. It is envisaged that this will be complete by 2015 leading to HTFPs becoming routine reference standards for radiometry and high temperature metrology.

  18. On the fixed points of monotonic operators in the critical case

    NASA Astrophysics Data System (ADS)

    Engibaryan, N. B.

    2006-10-01

    We consider the problem of constructing positive fixed points x of monotonic operators \\varphi acting on a cone K in a Banach space E. We assume that \\Vert\\varphi x\\Vert\\le\\Vert x\\Vert+\\gamma, \\gamma>0, for all x\\in K. In the case when \\varphi has a so-called non-trivial dissipation functional we construct a solution in an extension of E, which is a Banach space or a Fréchet space. We consider examples in which we prove the solubility of a conservative integral equation on the half-line with a sum-difference kernel, and of a non-linear integral equation of Urysohn type in the critical case.

  19. Infrared cameras are potential traceable "fixed points" for future thermometry studies.

    PubMed

    Yap Kannan, R; Keresztes, K; Hussain, S; Coats, T J; Bown, M J

    2015-01-01

    The National physical laboratory (NPL) requires "fixed points" whose temperatures have been established by the International Temperature Scale of 1990 (ITS 90) be used for device calibration. In practice, "near" blackbody radiators together with the standard platinum resistance thermometer is accepted as a standard. The aim of this study was to report the correlation and limits of agreement (LOA) of the thermal infrared camera and non-contact infrared temporal thermometer against each other and the "near" blackbody radiator. Temperature readings from an infrared thermography camera (FLIR T650sc) and a non-contact infrared temporal thermometer (Hubdic FS-700) were compared to a near blackbody (Hyperion R blackbody model 982) at 0.5 °C increments between 20-40 °C. At each increment, blackbody cavity temperature was confirmed with the platinum resistance thermometer. Measurements were taken initially with the thermal infrared camera followed by the infrared thermometer, with each device mounted in turn on a stand at a fixed distance of 20 cm and 5 cm from the blackbody aperture, respectively. The platinum thermometer under-estimated the blackbody temperature by 0.015 °C (95% LOA: -0.08 °C to 0.05 °C), in contrast to the thermal infrared camera and infrared thermometer which over-estimated the blackbody temperature by 0.16 °C (95% LOA: 0.03 °C to 0.28 °C) and 0.75 °C (95% LOA: -0.30 °C to 1.79 °C), respectively. Infrared thermometer over-estimates thermal infrared camera measurements by 0.6 °C (95% LOA: -0.46 °C to 1.65 °C). In conclusion, the thermal infrared camera is a potential temperature reference "fixed point" that could substitute mercury thermometers. However, further repeatability and reproducibility studies will be required with different models of thermal infrared cameras.

  20. Correlation Between Immersion Profile and Measured Value of Fixed-Point Temperature

    NASA Astrophysics Data System (ADS)

    Shulgat, O. S.; Fuksov, V. M.; Ivanova, A. G.; Gerasimov, S. F.; Pokhodun, A. I.

    2014-04-01

    Assessment of thermal immersion effects in the melting and freezing points defined by the International Temperature Scale of 1990 is one of the vital issues of modern thermometry. In documents of the Consultative Committee for Thermometry, the deviation of the experimental immersion profile from the theoretical value of the hydrostatic effect at a height of about 3 cm to 5 cm from the thermometer well bottom is used for the estimation of the uncertainty due to unwanted thermal effects. This estimation assumes the occurrence of solely the hydrostatic effect all along the height of the well inner wall. Real distortions of the temperature gradient at the bottom and at the top part of the well caused by the change of heat-exchange conditions are not taken into account. To define more precisely the temperature gradient along the height of the well, a miniature PRT with a 30 mm sensitive element and a sheath length and diameter of about 60 mm and 6 mm, respectively, were used. Also, the measurements of fixed-points temperature at noticeably different slopes of immersion profiles due to variations of the thermometer heat exchange and phase transition realization conditions were produced by means of a standard platinum resistance thermometer (SPRT). The measurements were carried out at the tin and zinc freezing points. The immersion curves measured with a miniature thermometer demonstrated an increase of the temperature during its lifting in the first 1 cm to 3 cm above the bottom of the well. The measurement results at the zinc freezing point by means of the SPRT have not confirmed the correlation between the immersion curves, the received value of the Zn freezing temperature, and the estimation of its uncertainty.

  1. An InGaAs detector based radiation thermometer and fixed-point blackbodies for temperature scale realization at NIM

    SciTech Connect

    Hao, X.; Yuan, Z.; Wang, J.; Lu, X.

    2013-09-11

    In this paper, we describe an InGaAs detector based radiation thermometer (IRT) and new design of fixed-point blackbodies, including Sn, Zn, Al and Cu, for the establishment of a temperature scale from 200 °C to 1085 °C at the National Institute of Metrology of China. The construction and calibration of the IRT with the four fixed-point blackbodies are described. Characteristics of the IRT, such as the size-of-source effect, the amplifier performance and its stability are determined. The design of the four fixed-points, with 10 mm diameter of aperture and 0.9999 emissivity, is described. The uncertainty of the scale realization is elaborated.

  2. An InGaAs detector based radiation thermometer and fixed-point blackbodies for temperature scale realization at NIM

    NASA Astrophysics Data System (ADS)

    Hao, X.; Yuan, Z.; Wang, J.; Lu, X.

    2013-09-01

    In this paper, we describe an InGaAs detector based radiation thermometer (IRT) and new design of fixed-point blackbodies, including Sn, Zn, Al and Cu, for the establishment of a temperature scale from 200 °C to 1085 °C at the National Institute of Metrology of China. The construction and calibration of the IRT with the four fixed-point blackbodies are described. Characteristics of the IRT, such as the size-of-source effect, the amplifier performance and its stability are determined. The design of the four fixed-points, with 10 mm diameter of aperture and 0.9999 emissivity, is described. The uncertainty of the scale realization is elaborated.

  3. Thermodynamic temperature determinations of Co C, Pd C, Pt C and Ru C eutectic fixed-point cells

    NASA Astrophysics Data System (ADS)

    Anhalt, K.; Hartmann, J.; Lowe, D.; Machin, G.; Sadli, M.; Yamada, Y.

    2006-04-01

    Thermodynamic temperatures during the melt and the freeze of Co-C, Pd-C, Pt-C and Ru-C metal-carbon fixed-point cells manufactured by LNE-INM/CNAM, NMIJ and NPL were determined by absolutely calibrated filter radiometers traceable to the PTB cryogenic radiometer and a radiance comparison method using an IKE LP3 radiation thermometer. The measurement uncertainties were below 400 mK at temperatures up to 2250 K. The results are in agreement within the combined uncertainties with a study on relative temperature differences of the same set of fixed-point cells. For the fixed-point cells manufactured by NPL the results are compared with a previous thermodynamic temperature measurement.

  4. Assessment of tungsten/rhenium thermocouples with metal-carbon eutectic fixed points up to 1500°C

    SciTech Connect

    Gotoh, M.

    2013-09-11

    Four Type A thermocouples and two Type C thermocouples were calibrated at the Au fixed point and Co-C and Pd-C eutectic fixed points. The thermocouples were exposed to 1330 °C for a total of 100 hours. The maximum drift due to the exposure was found to be 4.8 °C. The fixed-point calibration EMF of these thermocouples deviated by less than 0.86% from the temperature specified by the standards ASTM E230-2003 for Type C and GOSTR 8.585-2001 for Type A. The length of one of Type A thermocouples A52 is longer than the others by 150mm. Making use of this provision it was possible to place annealed part of A52 to the temperature gradient part of calibration arrangement every time. Therefore observed aging effect was as low as 0.5 °C compared to the other thermocouples.

  5. Artifact Removal from Biosignal using Fixed Point ICA Algorithm for Pre-processing in Biometric Recognition

    NASA Astrophysics Data System (ADS)

    Mishra, Puneet; Singla, Sunil Kumar

    2013-01-01

    In the modern world of automation, biological signals, especially Electroencephalogram (EEG) and Electrocardiogram (ECG), are gaining wide attention as a source of biometric information. Earlier studies have shown that EEG and ECG show versatility with individuals and every individual has distinct EEG and ECG spectrum. EEG (which can be recorded from the scalp due to the effect of millions of neurons) may contain noise signals such as eye blink, eye movement, muscular movement, line noise, etc. Similarly, ECG may contain artifact like line noise, tremor artifacts, baseline wandering, etc. These noise signals are required to be separated from the EEG and ECG signals to obtain the accurate results. This paper proposes a technique for the removal of eye blink artifact from EEG and ECG signal using fixed point or FastICA algorithm of Independent Component Analysis (ICA). For validation, FastICA algorithm has been applied to synthetic signal prepared by adding random noise to the Electrocardiogram (ECG) signal. FastICA algorithm separates the signal into two independent components, i.e. ECG pure and artifact signal. Similarly, the same algorithm has been applied to remove the artifacts (Electrooculogram or eye blink) from the EEG signal.

  6. Resource and Performance Evaluations of Fixed Point QRD-RLS Systolic Array through FPGA Implementation

    NASA Astrophysics Data System (ADS)

    Yokoyama, Yoshiaki; Kim, Minseok; Arai, Hiroyuki

    At present, when using space-time processing techniques with multiple antennas for mobile radio communication, real-time weight adaptation is necessary. Due to the progress of integrated circuit technology, dedicated processor implementation with ASIC or FPGA can be employed to implement various wireless applications. This paper presents a resource and performance evaluation of the QRD-RLS systolic array processor based on fixed-point CORDIC algorithm with FPGA. In this paper, to save hardware resources, we propose the shared architecture of a complex CORDIC processor. The required precision of internal calculation, the circuit area for the number of antenna elements and wordlength, and the processing speed will be evaluated. The resource estimation provides a possible processor configuration with a current FPGA on the market. Computer simulations assuming a fading channel will show a fast convergence property with a finite number of training symbols. The proposed architecture has also been implemented and its operation was verified by beamforming evaluation through a radio propagation experiment.

  7. Holographic duals of a family of Script N = 1* fixed points

    NASA Astrophysics Data System (ADS)

    Halmagyi, Nick; Pilch, Krzysztof; Römelsberger, Christian; Warner, Nicholas P.

    2006-08-01

    We construct a family of warped AdS5 compactifications of IIB supergravity that are the holographic duals of the complete set of Script N = 1* fixed points of a Bbb Z2 quiver gauge theory. This family interpolates between the T1,1 compactification with no three-form flux and the Bbb Z2 orbifold of the Pilch-Warner geometry which contains three-form flux. This family of solutions is constructed by making the most general Ansatz allowed by the symmetries of the field theory. We use Killing spinor methods because the symmetries impose two simple projection conditions on the Killing spinors, and these greatly reduce the problem. We see that generic interpolating solution has a nontrivial dilaton in the internal five-manifold. We calculate the central charge of the gauge theories from the supergravity backgrounds and find that it is (27/32) of the parent Script N = 2, quiver gauge theory. We believe that the projection conditions that we derived here will be useful for a much larger class of Script N = 1 holographic RG-flows.

  8. Realization of the WC-C peritectic fixed point at NIM and NMIJ

    SciTech Connect

    Wang, T.; Bai, C.; Yuan, Z.; Dong, W.; Lu, X.; Sasajima, N.; Yamada, Y.; Ara, C.

    2013-09-11

    Three WC-C peritectic fixed point cells, constructed from different sources of tungsten with different nominal purities, were measured at NIM and NMIJ. The three cells were constructed at NMIJ by NIM and NMIJ staffs, and T{sub 90} values of the three cells were measured at NMIJ during the period 31 Aug. to 25 Dec. 2009. Thereafter, the three cells were then transported to NIM, and T{sub 90} values of these cells were measured from 7 Dec. 2011 to 9 Jan. 2012. The results showed that T{sub 90} values of the three cells measured at the two institutes agreed within 0.4 °C with the combined scale comparison uncertainty of 1.7 °C (k= 2). The main component of the uncertainty is not the uncertainty due to impurities of the cells but the scale uncertainty and the stability of the measurement system. From these results it can be concluded that the WC-C cell is stable enough to provide new means of international high-temperature scale comparison above 3000 K.

  9. SU(4) Kondo effect in coupled quantum dots in parallel: Evidence of marginal fixed point

    NASA Astrophysics Data System (ADS)

    Eto, Mikio

    2008-03-01

    We theoretically study the Kondo effect in coupled quantum dots in parallel, using the scaling and NRG methods. The double quantum dots are capacitively coupled to each other, whereas they are attached to separate leads.ootnotetextA. Huebel, J. Weis and K.von Klitzing, 17th International Conference on the Electronic Properties of Two-Dimensional Systems (EP2DS, 2007). The SU(4) Kondo effect is realized when the energy levels are matched between the quantum dots. We show that (i) the Kondo temperature TK decreases with increasing |δ|, where δ is the level separation between the dots, obeying a power law [crossover from SU(4) to SU(2) Kondo effect]. (ii) The exponent of the power law is not a universal value in general.ootnotetextM. Eto, J. Phys. Soc. Jpn.74, 95 (2005). This is an evidence of the marginal fixed point of SU(4) Kondo effect.ootnotetextL. Borda et al., Phys. Rev. Lett. 90, 026602 (2003) (iii) The conductance through one of the quantum dots may show a non-monotonic behavior as a function of temperature T although the total conductance is a universal function of T/TK.

  10. Convergence analysis and numerical study of a fixed-point iterative method for solving systems of nonlinear equations.

    PubMed

    Huang, Na; Ma, Changfeng

    2014-01-01

    We present a fixed-point iterative method for solving systems of nonlinear equations. The convergence theorem of the proposed method is proved under suitable conditions. In addition, some numerical results are also reported in the paper, which confirm the good theoretical properties of our approach.

  11. Solving a system of Volterra-Fredholm integral equations of the second kind via fixed point method

    NASA Astrophysics Data System (ADS)

    Hasan, Talaat I.; Salleh, Shaharuddin; Sulaiman, Nejmaddin A.

    2015-12-01

    In this paper, we consider the system of Volterra-Fredholm integral equations of the second kind (SVFI-2). We propose fixed point method (FPM) to solve SVFI-2. In addition, a few theorems and new algorithm is introduced. They are supported by numerical examples and simulations using Matlab. The results are reasonably good when compared with the exact solutions.

  12. Vibrational eigen-modes of the 7.5-m thin meniscus mirror with axial and lateral fixed points.

    NASA Astrophysics Data System (ADS)

    Yamashita, Y.; Nishino, Y.

    Eigen-frequencies and modes are calculated for a thin meniscus mirror of diameter 7.5 m and thickness 20 cm, whose six degrees of freedom are confined by three axial and three lateral fixed points. The patterns calculated up to mode 25 are presented.

  13. Analysis of stability and bifurcations of fixed points and periodic solutions of a lumped model of neocortex with two delays

    PubMed Central

    2012-01-01

    A lumped model of neural activity in neocortex is studied to identify regions of multi-stability of both steady states and periodic solutions. Presence of both steady states and periodic solutions is considered to correspond with epileptogenesis. The model, which consists of two delay differential equations with two fixed time lags is mainly studied for its dependency on varying connection strength between populations. Equilibria are identified, and using linear stability analysis, all transitions are determined under which both trivial and non-trivial fixed points lose stability. Periodic solutions arising at some of these bifurcations are numerically studied with a two-parameter bifurcation analysis. PMID:22655859

  14. Unraveling expressionism

    NASA Astrophysics Data System (ADS)

    Truscott, Tadd; Darbois-Texier, Baptiste; Lovett, Benjamin; Brandenbourger, Martin; Maquet, Laurent; Pan, Zhao; Gilet, Tristan; Strivay, David; Dorbolo, Stéphane

    2015-11-01

    From the large facades of our buildings to the refinement of art canvas, paintings literally surround us and make our lives colorful. Artists are continually looking for novel methods to complement their expression and ideas, while instinctively manipulating the underlying physics. We attempt to unravel a phenomenon common to many modern canvas artists. In some paintings small droplets (0.1 - 5 mm) appear as a single color, however, on closer inspection are actually composed of multicolored spiral patterns (e.g., non-newtonian acrylic paint). High-speed imaging reveals that these assemblies occur when a droplet impinges on the edge of a small pool of paint. Upon impact, the droplet creates a crown with the falling droplet color on the inside of the crown and the pool colors on the outside. Ripping occurs in thin film feeding a rapid roll-up in the thicker ridge-line regions. These twisted formations are projected outward and break into small droplets that form the paint spirals. These beautiful formations, appreciated in their static form on canvas in museums around the world, are formed by equally beautiful physical phenomena.

  15. Formalin Fixed Paraffin Embedded Tissue as a Starting Point for PrPSc Detection by ELISA

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Introduction: Formalin fixed paraffin embedded tissue are regularly employed in TSE diagnosis by IHC, the standard by which all other diagnostic protocols are currently judged. While IHC affords advantages over diagnostic approaches that typically utilize fresh or frozen tissue, such as Western blot...

  16. Construction and in-situ characterisation of high-temperature fixed point cells devoted to industrial applications

    NASA Astrophysics Data System (ADS)

    Sadli, Mohamed; Bourson, Frédéric; Diril, Ahmet; Journeau, Christophe; Lowe, Dave; Parga, Clemente

    2014-08-01

    Among the activities of the European Metrology Research Programme (EMRP) project HiTeMS one work package is devoted to the development and testing of industrial solutions for long-standing temperature measurement problems at the highest temperatures. LNE-Cnam, NPL, TUBITAK-UME have worked on the design of high temperature fixed points (HTFP) suitable for in-situ temperature monitoring to be implemented in the facilities of CEA (Commissariat à l'énergie atomique et aux énergies alternatives). Several high temperature fixed point cells were constructed in these three national metrology institutes (NMIs) using a rugged version of cells based on the hybrid design of the laboratory HTFP developed and continuously improved at LNE-Cnam during the last years. The fixed points of interest were Co-C, Ru-C and Re-C corresponding to melting temperatures of 1324 °C, 1953 °C and 2474 °C respectively. The cells were characterised at the NMIs after their construction. Having proved robust enough, they were transported to CEA and tested in an induction furnace and cycled from room temperature to temperatures much above the melting temperatures (> +400 °C) with extremely high heating and cooling rates (up to 10 000 K/h). All the cells withstood the tests and the melting plateaus could be observed in all cases.

  17. The EuroSITES network: Integrating and enhancing fixed-point open ocean observatories around Europe

    NASA Astrophysics Data System (ADS)

    Lampitt, Richard S.; Larkin, Kate E.; EuroSITES Consortium

    2010-05-01

    EuroSITES is a 3 year (2008-2011) EU collaborative project (3.5MEuro) with the objective to integrate and enhance the nine existing open ocean fixed point observatories around Europe (www.eurosites.info). These observatories are primarily composed of full depth moorings and make multidisciplinary in situ observations within the water column as the European contribution to the global array OceanSITES (www.oceansites.org). In the first 18 months, all 9 observatories have been active and integration has been significant through the maintenance and enhancement of observatory hardware. Highlights include the enhancement of observatories with sensors to measure O2, pCO2, chlorophyll, and nitrate in near real-time from the upper 1000 m. In addition, some seafloor missions are also actively supported. These include seafloor platforms currently deployed in the Mediterranean, one for tsunami detection and one to monitor fluid flow related to seismic activity and slope stability. Upcoming seafloor science missions in 2010 include monitoring benthic biological communities and associated biogeochemistry as indicators of climate change in both the Northeast Atlantic and Mediterranean. EuroSITES also promotes the development of innovative sensors and samplers in order to progress capability to measure climate-relevant properties of the ocean. These include further developing current technologies for autonomous long-term monitoring of oxygen consumption in the mesopelagic, pH and mesozooplankton abundance. Many of these science missions are directly related to complementary activities in other European projects such as EPOCA, HYPOX and ESONET. In 2010 a direct collaboration including in situ field work will take place between ESONET and EuroSITES. The demonstration mission MODOO (funded by ESONET) will be implemented in 2010 at the EuroSITES PAP observatory. Field work will include deployment of a seafloor lander system with various sensors which will send data to shore in real

  18. Two-stage fixed-bed gasifier with selectable middle gas off-take point

    DOEpatents

    Strickland, Larry D.; Bissett, Larry A.

    1992-01-01

    A two-stage fixed bed coal gasifier wherein an annular region is in registry with a gasification zone underlying a devolatilization zone for extracting a side stream of high temperature substantially tar-free gas from the gasifier. A vertically displaceable skirt means is positioned within the gasifier to define the lower portion of the annular region so that vertical displacement of the skirt means positions the inlet into the annular region in a selected location within or in close proximity to the gasification zone for providing a positive control over the composition of the side stream gas.

  19. Criticality governed by the stable renormalization fixed point of the Ising model in the hierarchical small-world network.

    PubMed

    Nogawa, Tomoaki; Hasegawa, Takehisa; Nemoto, Koji

    2012-09-01

    We study the Ising model in a hierarchical small-world network by renormalization group analysis and find a phase transition between an ordered phase and a critical phase, which is driven by the coupling strength of the shortcut edges. Unlike ordinary phase transitions, which are related to unstable renormalization fixed points (FPs), the singularity in the ordered phase of the present model is governed by the FP that coincides with the stable FP of the ordered phase. The weak stability of the FP yields peculiar criticalities, including logarithmic behavior. On the other hand, the critical phase is related to a nontrivial FP, which depends on the coupling strength and is continuously connected to the ordered FP at the transition point. We show that this continuity indicates the existence of a finite correlation-length-like quantity inside the critical phase, which diverges upon approaching the transition point.

  20. On combining Thole's induced point dipole model with fixed charge distributions in molecular mechanics force fields.

    PubMed

    Antila, Hanne S; Salonen, Emppu

    2015-04-15

    The Thole induced point dipole model is combined with three different point charge fitting methods, Merz-Kollman (MK), charges from electrostatic potentials using a grid (CHELPG), and restrained electrostatic potential (RESP), and two multipole algorithms, distributed multipole analysis (DMA) and Gaussian multipole model (GMM), which can be used to describe the electrostatic potential (ESP) around molecules in molecular mechanics force fields. This is done to study how the different methods perform when intramolecular polarizability contributions are self-consistently removed from the fitting done in the force field parametrization. It is demonstrated that the polarizable versions of the partial charge models provide a good compromise between accuracy and computational efficiency in describing the ESP of small organic molecules undergoing conformational changes. For the point charge models, the inclusion of polarizability reduced the the average root mean square error of ESP over the test set by 4-10%.

  1. Investigations on Two Co-C Fixed-Point Cells Prepared at INRIM and LNE-Cnam

    NASA Astrophysics Data System (ADS)

    Battuello, M.; Florio, M.; Sadli, M.; Bourson, F.

    2011-08-01

    INRIM and LNE-Cnam agreed to undertake a collaboration aimed to verify, through the use of metal-carbon eutectic fixed-point cells, methods and facilities used for defining the transition temperature of eutectic fixed points and manufacturing procedures of cells. To this purpose and as a first step of the cooperation, a Co-C cell manufactured at LNE-Cnam was measured at INRIM and compared with a local cell. The two cells were of different designs: the INRIM cell of 10 cm3 inner volume and the LNE-Cnam one of 3.9 cm3. The external dimensions of the two cells were noticeably different, namely, 40 mm in length and 24 mm in diameter for the LNE-Cnam cell 3Co4 and 110 mm in length and 42 mm in diameter for the INRIM cell. Consequently, the investigation of the effect of temperature distributions in the heating furnace was undertaken by implementing the cells inside single-zone and three-zone furnaces. The transition temperature of the cell was determined at the two institutes making use of different techniques: at INRIM radiation scales at 900 nm, 950 nm, and 1.6 μm were realized from In to Cu and then used to define T 90(Co-C) by extrapolation. At LNE-Cnam, a radiance comparator based on a grating monochromator was used for the extrapolation from the Cu fixed point. This paper presents a comparative description of the cells and the manufacturing methods and the results in terms of equivalence between the two cells and melting temperatures determined at INRIM and LNE-Cnam.

  2. Generating functionals for harmonic expectation values of paths with fixed end points: Feynman diagrams for nonpolynomial interactions.

    PubMed

    Kleinert, H; Pelster, A; Bachmann, M

    1999-09-01

    We introduce a general class of generating functionals for the calculation of quantum-mechanical expectation values of arbitrary functionals of fluctuating paths with fixed end points in configuration or momentum space. The generating functionals are calculated explicitly for the harmonic oscillator with time-dependent frequency, and used to derive a smearing formula for correlation functions of polynomial and nonpolynomial functions of time-dependent positions and momenta. This formula summarizes the effect of quantum fluctuations, and serves to derive generalized Wick rules and Feynman diagrams for perturbation expansions of nonpolynomial interactions.

  3. SU-E-T-539: Fixed Versus Variable Optimization Points in Combined-Mode Modulated Arc Therapy Planning

    SciTech Connect

    Kainz, K; Prah, D; Ahunbay, E; Li, X

    2014-06-01

    Purpose: A novel modulated arc therapy technique, mARC, enables superposition of step-and-shoot IMRT segments upon a subset of the optimization points (OPs) of a continuous-arc delivery. We compare two approaches to mARC planning: one with the number of OPs fixed throughout optimization, and another where the planning system determines the number of OPs in the final plan, subject to an upper limit defined at the outset. Methods: Fixed-OP mARC planning was performed for representative cases using Panther v. 5.01 (Prowess, Inc.), while variable-OP mARC planning used Monaco v. 5.00 (Elekta, Inc.). All Monaco planning used an upper limit of 91 OPs; those OPs with minimal MU were removed during optimization. Plans were delivered, and delivery times recorded, on a Siemens Artiste accelerator using a flat 6MV beam with 300 MU/min rate. Dose distributions measured using ArcCheck (Sun Nuclear Corporation, Inc.) were compared with the plan calculation; the two were deemed consistent if they agreed to within 3.5% in absolute dose and 3.5 mm in distance-to-agreement among > 95% of the diodes within the direct beam. Results: Example cases included a prostate and a head-and-neck planned with a single arc and fraction doses of 1.8 and 2.0 Gy, respectively. Aside from slightly more uniform target dose for the variable-OP plans, the DVHs for the two techniques were similar. For the fixed-OP technique, the number of OPs was 38 and 39, and the delivery time was 228 and 259 seconds, respectively, for the prostate and head-and-neck cases. For the final variable-OP plans, there were 91 and 85 OPs, and the delivery time was 296 and 440 seconds, correspondingly longer than for fixed-OP. Conclusion: For mARC, both the fixed-OP and variable-OP approaches produced comparable-quality plans whose delivery was successfully verified. To keep delivery time per fraction short, a fixed-OP planning approach is preferred.

  4. Mechanical behavior analysis of a submerged fixed point anchoring system for a hydroacoustic signature measuring sensor for divers and ships

    NASA Astrophysics Data System (ADS)

    Slamnoiu, G.; Radu, O.; Surdu, G.; Roşca, V.; Damian, R.; Pascu, C.; Curcă, E.; Rădulescu, A.

    2016-08-01

    The paper has as its main objectives the presentation and the analysis of the numerical analysis results for the study of a fixed point anchoring system for a hydroacoustic sensor when measuring the hydroacoustic signature of divers and ships in real sea conditions. The study of the mechanical behavior of this system has as main objectives the optimization of the shape and weight of the anchorage ballast for the metallic structure while considering the necessity to maintain the sensor in a fixed point and the analysis of the sensor movements and the influences on the measurements caused by the sea current streams. The study was focused on the 3D model of metallic structure design; numerical modeling of the water flow around the sensor anchoring structure using volume of fluid analysis and the analysis of the forces and displacements using FEM when needed for the study. In this paper we have used data for the sea motion dynamics and in particular the velocity of the sea current streams as determined by experimental measurements that have been conducted for the western area of the Black Sea.

  5. Low-energy fixed points of the σ-τ and the O(3) symmetric Anderson models

    NASA Astrophysics Data System (ADS)

    Bulla, R.; Hewson, A. C.; Zhang, G.-M.

    1997-11-01

    We study the single-channel (compactified) models, the σ-τ model, and the O(3) symmetric Anderson model, which were introduced by Coleman et al., and Coleman and Schofield, as a simplified way to understand the low-energy behavior of the isotropic and anisotropic two-channel Kondo systems. These models display both Fermi-liquid and marginal-Fermi-liquid behavior and an understanding of the nature of their low-energy fixed points may give some general insights into the low-energy behavior of other strongly correlated systems. We calculate the excitation spectrum at the non-Fermi-liquid fixed point of the σ-τ model using conformal field theory, and show that the results are in agreement with those obtained in recent numerical renormalization group (NRG) calculations. For the O(3) Anderson model we find further logarithmic corrections in the weak-coupling perturbation expansion to those obtained in earlier calculations, such that the renormalized interaction term now becomes marginally stable rather than marginally unstable. We derive a Ward identity and a renormalized form of the perturbation theory that encompasses both the weak- and strong-coupling regimes and show that the χ/γ ratio is 8/3 (χ is the total susceptibility, spin plus isospin), independent of the interaction U and in agreement with the NRG calculations.

  6. Audio video based fast fixed-point independent vector analysis for multisource separation in a room environment

    NASA Astrophysics Data System (ADS)

    Liang, Yanfeng; Naqvi, Syed Mohsen; Chambers, Jonathon A.

    2012-12-01

    Fast fixed-point independent vector analysis (FastIVA) is an improved independent vector analysis (IVA) method, which can achieve faster and better separation performance than original IVA. As an example IVA method, it is designed to solve the permutation problem in frequency domain independent component analysis by retaining the higher order statistical dependency between frequencies during learning. However, the performance of all IVA methods is limited due to the dimensionality of the parameter space commonly encountered in practical frequency-domain source separation problems and the spherical symmetry assumed with the source model. In this article, a particular permutation problem encountered in using the FastIVA algorithm is highlighted, namely the block permutation problem. Therefore a new audio video based fast fixed-point independent vector analysis algorithm is proposed, which uses video information to provide a smart initialization for the optimization problem. The method cannot only avoid the ill convergence resulting from the block permutation problem but also improve the separation performance even in noisy and high reverberant environments. Different multisource datasets including the real audio video corpus AV16.3 are used to verify the proposed method. For the evaluation of the separation performance on real room recordings, a new pitch based evaluation criterion is also proposed.

  7. Typical Orbits of Quadratic Polynomials with a Neutral Fixed Point: Brjuno Type

    NASA Astrophysics Data System (ADS)

    Cheraghi, Davoud

    2013-09-01

    We describe the topological behavior of typical orbits of complex quadratic polynomials {P_{α}(z) = e^{2 π α {i}} z + z2}, with α of high return type. Here we prove that for such Brjuno values of α the closure of the critical orbit, which is the measure theoretic attractor of the map, has zero area. Then we show that the limit set of the orbit of a typical point in the Julia set of P α is equal to the closure of the critical orbit. Our method is based on the near parabolic renormalization of Inou-Shishikura, and a uniform optimal estimate on the derivative of the Fatou coordinate that we prove here.

  8. Construction of Home-Made Tin Fixed-Point Cell at TUBITAK UME

    NASA Astrophysics Data System (ADS)

    Kalemci, M.; Arifovic, N.; Bağçe, A.; Aytekin, S. O.; Ince, A. T.

    2015-08-01

    TUBITAK UME Temperature Laboratory initiated a new study which focuses on the construction of a tin freezing-point cell as a primary temperature standard. The design is an open-cell type similar to the National Institute of Standards and Technology design. With this aim, a brand new vacuum and filling line employing an oil diffusion pump and two cold traps (liquid nitrogen and dry ice) was set-up. The graphite parts (crucible, thermometer well, etc.) have been baked at high temperature under vacuum. Each cell was filled with approximately 1 kg of high-purity tin (99.9999 %) in a three-zone furnace. Then several melting and freezing curves were obtained to assess the quality of the home-made cell, and also the new cell was compared with the existing reference cell of the laboratory. The results obtained are very close to the reference cell of UME, indicating that the method used for fabrication was promising and satisfactory and also seems to meet the requirements to have a primary level temperature standard.

  9. A Phase-Field Solidification Model of Almost Pure ITS-90 Fixed Points

    NASA Astrophysics Data System (ADS)

    Large, M. J.; Pearce, J. V.

    2014-07-01

    A two-dimensional axisymmetric phase-field model of thermo-solutal solidification in freezing-point cells used for calibrating standard platinum resistance thermometers for realization and dissemination of the International Temperature Scale of 1990 is presented. The cell is essentially a graphite crucible containing an ingot of very pure metal (of order 99.9999 %). A graphite tube is inserted along the axis of the ingot to enable immersion of the thermometer in the metal. In this study, the metal is tin (freezing temperature of ). During the freezing of these cells, a steady, reproducible temperature is realized, with a defined temperature that can be used to calibrate thermometers with uncertainties mK. The model is applied to understand the effect of experimental parameters, such as initiation technique and furnace homogeneity, on the measured freezing curve. Results show that freezing curves whose behavior is consistent with the Scheil theory of solidification can be obtained with a specific furnace temperature profile, and provided that the freeze is of a long duration, the results are consistent with previous one-dimensional models and experiments. Morphological instability is observed with the inner interface initiation technique, causing the interface to adopt a cellular structure. This elevates the measured temperature, in accordance with the Gibbs-Thomson effect. In addition, the influence of initiation techniques on the solidification behavior is examined. The model indicates that an initially smooth inner mantle can `de-wet' from the thermometer well-forming agglomerated solid droplets, following recalescence, under certain conditions. This manifests as a measured temperature depression due to the Gibbs-Thomson effect, with a magnitude of to in simulations. The temperature rises to that of the stable outer mantle as freezing progresses and the droplets re-melt. It is demonstrated that the effect occurs below a critical mantle thickness. A physical

  10. Characterizing the size distribution of particles in urban stormwater by use of fixed-point sample-collection methods

    USGS Publications Warehouse

    Selbig, William R.; Bannerman, Roger T.

    2011-01-01

    The U.S Geological Survey, in cooperation with the Wisconsin Department of Natural Resources (WDNR) and in collaboration with the Root River Municipal Stormwater Permit Group monitored eight urban source areas representing six types of source areas in or near Madison, Wis. in an effort to improve characterization of particle-size distributions in urban stormwater by use of fixed-point sample collection methods. The types of source areas were parking lot, feeder street, collector street, arterial street, rooftop, and mixed use. This information can then be used by environmental managers and engineers when selecting the most appropriate control devices for the removal of solids from urban stormwater. Mixed-use and parking-lot study areas had the lowest median particle sizes (42 and 54 (u or mu)m, respectively), followed by the collector street study area (70 (u or mu)m). Both arterial street and institutional roof study areas had similar median particle sizes of approximately 95 (u or mu)m. Finally, the feeder street study area showed the largest median particle size of nearly 200 (u or mu)m. Median particle sizes measured as part of this study were somewhat comparable to those reported in previous studies from similar source areas. The majority of particle mass in four out of six source areas was silt and clay particles that are less than 32 (u or mu)m in size. Distributions of particles ranging from 500 (u or mu)m were highly variable both within and between source areas. Results of this study suggest substantial variability in data can inhibit the development of a single particle-size distribution that is representative of stormwater runoff generated from a single source area or land use. Continued development of improved sample collection methods, such as the depth-integrated sample arm, may reduce variability in particle-size distributions by mitigating the effect of sediment bias inherent with a fixed-point sampler.

  11. Experiments with powdered CMN thermometers between 10 mK and 4K, and a comparison with an NBS SRM 768 fixed-point device

    SciTech Connect

    Fogle, W.E.; Hornung, E.W.; Mayberry, M.C.; Phillips, N.E.

    1981-08-01

    Comparison of a powdered CMN thermometer with an NBS fixed point device demonstrates an internal inconsistency in the T/sub c/'s assigned to the fixed point device. T/sub c/'s between 100 and 200 mK are in excellent agreement with a temperature scale interpolated between He vapor pressure temperatures and nuclear orientation temperatures, but there is a discrepancy of 8% at the 15 mK point. Evidence for different susceptibility-temperature relations for superficially similar CMN thermometers is also presented.

  12. Investigation of ternary and quaternary high-temperature fixed-point cells, based on platinum–carbon-X, as blind comparison artefacts

    NASA Astrophysics Data System (ADS)

    Dong, W.; Machin, G.; Bloembergen, P.; Lowe, D.; Wang, T.

    2016-11-01

    Extensive studies of platinum–carbon eutectic alloy based high temperature fixed point cells have shown that this alloy has extremely good metrological potential as a temperature reference. However, it’s possible adoption as an accepted reference standard means that its eutectic temperature value will soon be agreed with an uncertainty less than most radiation thermometry scales at that temperature. Thus it will lack credibility if used as a future scale comparison artefact. To avoid this, the fixed-point cell can be deliberately doped with an impurity to change its transition temperature by an amount sufficient to test the accuracy of the scales of the institutes, involved in the comparison. In this study dopants of palladium and iridium were added to platinum–carbon to produce ternary alloy and quaternary alloy fixed-point cells. The stability of these artefacts was demonstrated and the fixed-point cells were used to compare the ITS-90 scales of NIM and NPL. It was found that the fixed point temperatures could be changed by an appreciable amount while retaining the stability and repeatability required for comparison artefacts.

  13. A comparison of the NPL and LNE-Cnam silver and copper fixed-point blackbody sources, and measurement of the silver/copper temperature interval

    NASA Astrophysics Data System (ADS)

    McEvoy, H. C.; Sadli, M.; Bourson, F.; Briaudeau, S.; Rougié, B.

    2013-12-01

    The silver and copper fixed-point blackbody sources of NPL were directly compared with those of LNE-Cnam using an IKE LP3 and an IKE LP5 at three wavelengths (650 nm, 795 nm and 903 nm). The two silver fixed points and the two copper fixed points were in excellent agreement with each other, with a difference of 11 mK for the silver and within 16 mK for the copper, with an expanded measurement uncertainty of between 10 mK and 20 mK depending on the pyrometer used. The temperature interval between the silver and copper freezing points was also measured using combinations of all four fixed points. The results with the NPL LP3 gave a value for the silver-copper temperature interval of 122.89 °C with an expanded uncertainty of 30 mK those with the LNE-Cnam LP5 gave a temperature interval of 122.87 °C also with an expanded uncertainty of 30 mK this compares with the ITS-90 value of 122.84 °C.

  14. A Comparison of Deterministic and Stochastic Modeling Approaches for Biochemical Reaction Systems: On Fixed Points, Means, and Modes

    PubMed Central

    Hahl, Sayuri K.; Kremling, Andreas

    2016-01-01

    In the mathematical modeling of biochemical reactions, a convenient standard approach is to use ordinary differential equations (ODEs) that follow the law of mass action. However, this deterministic ansatz is based on simplifications; in particular, it neglects noise, which is inherent to biological processes. In contrast, the stochasticity of reactions is captured in detail by the discrete chemical master equation (CME). Therefore, the CME is frequently applied to mesoscopic systems, where copy numbers of involved components are small and random fluctuations are thus significant. Here, we compare those two common modeling approaches, aiming at identifying parallels and discrepancies between deterministic variables and possible stochastic counterparts like the mean or modes of the state space probability distribution. To that end, a mathematically flexible reaction scheme of autoregulatory gene expression is translated into the corresponding ODE and CME formulations. We show that in the thermodynamic limit, deterministic stable fixed points usually correspond well to the modes in the stationary probability distribution. However, this connection might be disrupted in small systems. The discrepancies are characterized and systematically traced back to the magnitude of the stoichiometric coefficients and to the presence of nonlinear reactions. These factors are found to synergistically promote large and highly asymmetric fluctuations. As a consequence, bistable but unimodal, and monostable but bimodal systems can emerge. This clearly challenges the role of ODE modeling in the description of cellular signaling and regulation, where some of the involved components usually occur in low copy numbers. Nevertheless, systems whose bimodality originates from deterministic bistability are found to sustain a more robust separation of the two states compared to bimodal, but monostable systems. In regulatory circuits that require precise coordination, ODE modeling is thus still

  15. A Comparison of Deterministic and Stochastic Modeling Approaches for Biochemical Reaction Systems: On Fixed Points, Means, and Modes

    PubMed Central

    Hahl, Sayuri K.; Kremling, Andreas

    2016-01-01

    In the mathematical modeling of biochemical reactions, a convenient standard approach is to use ordinary differential equations (ODEs) that follow the law of mass action. However, this deterministic ansatz is based on simplifications; in particular, it neglects noise, which is inherent to biological processes. In contrast, the stochasticity of reactions is captured in detail by the discrete chemical master equation (CME). Therefore, the CME is frequently applied to mesoscopic systems, where copy numbers of involved components are small and random fluctuations are thus significant. Here, we compare those two common modeling approaches, aiming at identifying parallels and discrepancies between deterministic variables and possible stochastic counterparts like the mean or modes of the state space probability distribution. To that end, a mathematically flexible reaction scheme of autoregulatory gene expression is translated into the corresponding ODE and CME formulations. We show that in the thermodynamic limit, deterministic stable fixed points usually correspond well to the modes in the stationary probability distribution. However, this connection might be disrupted in small systems. The discrepancies are characterized and systematically traced back to the magnitude of the stoichiometric coefficients and to the presence of nonlinear reactions. These factors are found to synergistically promote large and highly asymmetric fluctuations. As a consequence, bistable but unimodal, and monostable but bimodal systems can emerge. This clearly challenges the role of ODE modeling in the description of cellular signaling and regulation, where some of the involved components usually occur in low copy numbers. Nevertheless, systems whose bimodality originates from deterministic bistability are found to sustain a more robust separation of the two states compared to bimodal, but monostable systems. In regulatory circuits that require precise coordination, ODE modeling is thus still

  16. A Comparison of Deterministic and Stochastic Modeling Approaches for Biochemical Reaction Systems: On Fixed Points, Means, and Modes.

    PubMed

    Hahl, Sayuri K; Kremling, Andreas

    2016-01-01

    In the mathematical modeling of biochemical reactions, a convenient standard approach is to use ordinary differential equations (ODEs) that follow the law of mass action. However, this deterministic ansatz is based on simplifications; in particular, it neglects noise, which is inherent to biological processes. In contrast, the stochasticity of reactions is captured in detail by the discrete chemical master equation (CME). Therefore, the CME is frequently applied to mesoscopic systems, where copy numbers of involved components are small and random fluctuations are thus significant. Here, we compare those two common modeling approaches, aiming at identifying parallels and discrepancies between deterministic variables and possible stochastic counterparts like the mean or modes of the state space probability distribution. To that end, a mathematically flexible reaction scheme of autoregulatory gene expression is translated into the corresponding ODE and CME formulations. We show that in the thermodynamic limit, deterministic stable fixed points usually correspond well to the modes in the stationary probability distribution. However, this connection might be disrupted in small systems. The discrepancies are characterized and systematically traced back to the magnitude of the stoichiometric coefficients and to the presence of nonlinear reactions. These factors are found to synergistically promote large and highly asymmetric fluctuations. As a consequence, bistable but unimodal, and monostable but bimodal systems can emerge. This clearly challenges the role of ODE modeling in the description of cellular signaling and regulation, where some of the involved components usually occur in low copy numbers. Nevertheless, systems whose bimodality originates from deterministic bistability are found to sustain a more robust separation of the two states compared to bimodal, but monostable systems. In regulatory circuits that require precise coordination, ODE modeling is thus still

  17. A Comparison of Deterministic and Stochastic Modeling Approaches for Biochemical Reaction Systems: On Fixed Points, Means, and Modes.

    PubMed

    Hahl, Sayuri K; Kremling, Andreas

    2016-01-01

    In the mathematical modeling of biochemical reactions, a convenient standard approach is to use ordinary differential equations (ODEs) that follow the law of mass action. However, this deterministic ansatz is based on simplifications; in particular, it neglects noise, which is inherent to biological processes. In contrast, the stochasticity of reactions is captured in detail by the discrete chemical master equation (CME). Therefore, the CME is frequently applied to mesoscopic systems, where copy numbers of involved components are small and random fluctuations are thus significant. Here, we compare those two common modeling approaches, aiming at identifying parallels and discrepancies between deterministic variables and possible stochastic counterparts like the mean or modes of the state space probability distribution. To that end, a mathematically flexible reaction scheme of autoregulatory gene expression is translated into the corresponding ODE and CME formulations. We show that in the thermodynamic limit, deterministic stable fixed points usually correspond well to the modes in the stationary probability distribution. However, this connection might be disrupted in small systems. The discrepancies are characterized and systematically traced back to the magnitude of the stoichiometric coefficients and to the presence of nonlinear reactions. These factors are found to synergistically promote large and highly asymmetric fluctuations. As a consequence, bistable but unimodal, and monostable but bimodal systems can emerge. This clearly challenges the role of ODE modeling in the description of cellular signaling and regulation, where some of the involved components usually occur in low copy numbers. Nevertheless, systems whose bimodality originates from deterministic bistability are found to sustain a more robust separation of the two states compared to bimodal, but monostable systems. In regulatory circuits that require precise coordination, ODE modeling is thus still

  18. Strong convergence theorems for a common fixed point of a finite family of Bregman weak relativity nonexpansive mappings in reflexive Banach spaces.

    PubMed

    Zegeye, Habtu; Shahzad, Naseer

    2014-01-01

    We introduce an iterative process for finding an element of a common fixed point of a finite family of Bregman weak relatively nonexpansive mappings. Our theorems improve and unify most of the results that have been proved for this important class of nonlinear operators.

  19. Strong Convergence Theorems for a Common Fixed Point of a Finite Family of Bregman Weak Relativity Nonexpansive Mappings in Reflexive Banach Spaces

    PubMed Central

    2014-01-01

    We introduce an iterative process for finding an element of a common fixed point of a finite family of Bregman weak relatively nonexpansive mappings. Our theorems improve and unify most of the results that have been proved for this important class of nonlinear operators. PMID:24757423

  20. Analogies between the Torque-Free Motion of a Rigid Body about a Fixed Point and Light Propagation in Anisotropic Media

    ERIC Educational Resources Information Center

    Bellver-Cebreros, Consuelo; Rodriguez-Danta, Marcelo

    2009-01-01

    An apparently unnoticed analogy between the torque-free motion of a rotating rigid body about a fixed point and the propagation of light in anisotropic media is stated. First, a new plane construction for visualizing this torque-free motion is proposed. This method uses an intrinsic representation alternative to angular momentum and independent of…

  1. Centrifugal multiplexing fixed-volume dispenser on a plastic lab-on-a-disk for parallel biochemical single-end-point assays.

    PubMed

    La, Moonwoo; Park, Sang Min; Kim, Dong Sung

    2015-01-01

    In this study, a multiple sample dispenser for precisely metered fixed volumes was successfully designed, fabricated, and fully characterized on a plastic centrifugal lab-on-a-disk (LOD) for parallel biochemical single-end-point assays. The dispenser, namely, a centrifugal multiplexing fixed-volume dispenser (C-MUFID) was designed with microfluidic structures based on the theoretical modeling about a centrifugal circumferential filling flow. The designed LODs were fabricated with a polystyrene substrate through micromachining and they were thermally bonded with a flat substrate. Furthermore, six parallel metering and dispensing assays were conducted at the same fixed-volume (1.27 μl) with a relative variation of ±0.02 μl. Moreover, the samples were metered and dispensed at different sub-volumes. To visualize the metering and dispensing performances, the C-MUFID was integrated with a serpentine micromixer during parallel centrifugal mixing tests. Parallel biochemical single-end-point assays were successfully conducted on the developed LOD using a standard serum with albumin, glucose, and total protein reagents. The developed LOD could be widely applied to various biochemical single-end-point assays which require different volume ratios of the sample and reagent by controlling the design of the C-MUFID. The proposed LOD is feasible for point-of-care diagnostics because of its mass-producible structures, reliable metering/dispensing performance, and parallel biochemical single-end-point assays, which can identify numerous biochemical.

  2. Centrifugal multiplexing fixed-volume dispenser on a plastic lab-on-a-disk for parallel biochemical single-end-point assays

    PubMed Central

    La, Moonwoo; Park, Sang Min; Kim, Dong Sung

    2015-01-01

    In this study, a multiple sample dispenser for precisely metered fixed volumes was successfully designed, fabricated, and fully characterized on a plastic centrifugal lab-on-a-disk (LOD) for parallel biochemical single-end-point assays. The dispenser, namely, a centrifugal multiplexing fixed-volume dispenser (C-MUFID) was designed with microfluidic structures based on the theoretical modeling about a centrifugal circumferential filling flow. The designed LODs were fabricated with a polystyrene substrate through micromachining and they were thermally bonded with a flat substrate. Furthermore, six parallel metering and dispensing assays were conducted at the same fixed-volume (1.27 μl) with a relative variation of ±0.02 μl. Moreover, the samples were metered and dispensed at different sub-volumes. To visualize the metering and dispensing performances, the C-MUFID was integrated with a serpentine micromixer during parallel centrifugal mixing tests. Parallel biochemical single-end-point assays were successfully conducted on the developed LOD using a standard serum with albumin, glucose, and total protein reagents. The developed LOD could be widely applied to various biochemical single-end-point assays which require different volume ratios of the sample and reagent by controlling the design of the C-MUFID. The proposed LOD is feasible for point-of-care diagnostics because of its mass-producible structures, reliable metering/dispensing performance, and parallel biochemical single-end-point assays, which can identify numerous biochemical. PMID:25610516

  3. Modification and fixed-point analysis of a Kalman filter for orientation estimation based on 9D inertial measurement unit data.

    PubMed

    Brückner, Hans-Peter; Spindeldreier, Christian; Blume, Holger

    2013-01-01

    A common approach for high accuracy sensor fusion based on 9D inertial measurement unit data is Kalman filtering. State of the art floating-point filter algorithms differ in their computational complexity nevertheless, real-time operation on a low-power microcontroller at high sampling rates is not possible. This work presents algorithmic modifications to reduce the computational demands of a two-step minimum order Kalman filter. Furthermore, the required bit-width of a fixed-point filter version is explored. For evaluation real-world data captured using an Xsens MTx inertial sensor is used. Changes in computational latency and orientation estimation accuracy due to the proposed algorithmic modifications and fixed-point number representation are evaluated in detail on a variety of processing platforms enabling on-board processing on wearable sensor platforms. PMID:24110597

  4. The Humanities, Unraveled

    ERIC Educational Resources Information Center

    Berube, Michael

    2013-01-01

    Graduate education in the humanities is in crisis. Every aspect, from the most specific details of the curriculum to the broadest questions about its purpose, is in crisis. It is a seamless garment of crisis: If one pulls on any one thread, the entire thing unravels. It is therefore exceptionally difficult to discuss any one aspect of graduate…

  5. Co-C and Pd-C Fixed Points for the Evaluation of Facilities and Scales Realization at INRIM and NMC

    NASA Astrophysics Data System (ADS)

    Battuello, M.; Wang, L.; Girard, F.; Ang, S. H.

    2014-04-01

    Two hybrid cells for realizing the Co-C and Pd-C fixed points and constructed at Istituto Nazionale di Ricerca Metrologica (INRIM) were used for an evaluation of facilities and procedures adopted by INRIM and National Metrology Institute of Singapore (NMC) for the realization of the solid-liquid phase transitions of high-temperature fixed points and for determining their transition temperatures. Four different furnaces were used for the investigations, i.e., two single-zone furnaces, one of them of the direct-heating type, and two identical three-zone furnaces. The transition temperatures were measured at both institutes by adopting different procedures for realizing the radiation scales, i.e., at INRIM a scheme based on the extrapolation of fixed-point interpolated scales and an International Temperature Scale of 1990 (ITS-90) approach at NMC. The point of inflection (POI) of the melting curves was determined and assumed as a practical representation of the melting temperature. Different methods for deriving the POI were used, and differences as large as some hundredths of a kelvin were found with the different approaches. The POIs of the different melting curves were analyzed with respect to the different possible operative conditions with the aim of deriving reproducibility figures to improve the estimated uncertainty. As regard to the institutes inter-comparison, differences of 0.13 K and 0.29 K were found between INRIM and NMC determinations at the Co-C and Pd-C points, respectively. Such differences are compatible with the combined standard uncertainties of the comparison, which are estimated to be 0.33 K and 0.36 K at the Co-C and Pd-C points, respectively.

  6. A Nondestructive Evaluation Method: Measuring the Fixed Strength of Spot-Welded Joint Points by Surface Electrical Resistivity.

    PubMed

    Shimamoto, Akira; Yamashita, Keitaro; Inoue, Hirofumi; Yang, Sung-Mo; Iwata, Masahiro; Ike, Natsuko

    2013-04-01

    Destructive tests are generally applied to evaluate the fixed strength of spot-welding nuggets of zinc-plated steel (which is a widely used primary structural material for automobiles). These destructive tests, however, are expensive and time-consuming. This paper proposes a nondestructive method for evaluating the fixed strength of the welded joints using surface electrical resistance. A direct current nugget-tester and probes have been developed by the authors for this purpose. The proposed nondestructive method uses the relative decrease in surface electrical resistance, α. The proposed method also considers the effect of the corona bond. The nugget diameter is estimated by two factors: R Quota, which is calculated from variation of resistance, and a constant that represents the area of the corona bond. Since the maximum tensile strength is correlated with the nugget diameter, it can be inferred from the estimated nugget diameter. When appropriate measuring conditions for the surface electrical resistance are chosen, the proposed method can effectively evaluate the fixed strength of the spot-welded joints even if the steel sheet is zinc-plated.

  7. The NIST eutectic project: construction of Co C, Pt C and Re C fixed-point cells and their comparison with the NMIJ

    NASA Astrophysics Data System (ADS)

    Sasajima, N.; Yoon, H. W.; Gibson, C. E.; Khromchenko, V.; Sakuma, F.; Yamada, Y.

    2006-04-01

    The National Institute of Standards and Technology (NIST) has initiated a project on novel high-temperature fixed-points by use of metal (carbide)-carbon eutectics to lower uncertainties in thermodynamic temperature measurement. As the first stage of the NIST eutectic project, a comparison of Co-C, Pt-C and Re-C eutectic fixed-point cells was conducted between the NIST and the National Metrology Institute of Japan (NMIJ) at the NIST to verify the quality of the NIST eutectic cells in addition to checking for possible furnace and radiation thermometer effects on the eutectic fixed-point realizations. In the comparison, two high-temperature furnaces, two radiation thermometers and one gold-point blackbody were used. A Nagano M furnace and a Linear Pyrometer 3 radiation thermometer were transferred from NMIJ and were used in conjunction with a Thermo Gauge furnace and an Absolute Pyrometer 1 radiation thermometer of NIST to check the dependence on the measurement equipment. The results showed that Co-C cells agreed to 73 mK. The melting temperature of the NIST Pt-C cell was approximately 270 mK lower than that of the NMIJ cell, with a comparison uncertainty of roughly 110 mK (k = 2), due to the poor purity of Pt powder. Although the Re-C comparison showed instability of the comparison system, they agreed within 100 mK. Though further improvement is necessary for the Pt-C cell, such as the use of higher purity Pt, the filling and measuring technique has been established at the NIST.

  8. The optimal launching of a space vehicle from the surface of the moon to a fixed point on the circular orbit of its artificial satellite

    NASA Astrophysics Data System (ADS)

    Grigor'ev, K. G.; Zapletina, E. V.; Zapletin, M. P.

    1992-06-01

    The paper presents an analysis and results of a numerical solution, based on the maximum principle, of three types of problems concerning the optimal launching of a space vehicle with a high-thrust rocket engine from the lunar surface to a fixed point on the circular orbit of a lunar artificial satellite. Attention is given to the problems of the fastest possible launching time, launching with minimal mass expenditure, and minimal trade-off functional (a compromise between expenditures for launch time and mass). The shooting method is used to obtain exact numerical solutions for the appropriate maximum principle boundary problems.

  9. Zinc-Bismuth and Aluminum-Indium Monotectic Alloy-Based Fixed-Point Cells with Double Phase Transition for In Situ Calibration of Thermocouples

    NASA Astrophysics Data System (ADS)

    Lowe, Dave; Kodwani, Darsh

    2015-11-01

    Re-calibration of a thermocouple after it has been installed in a process is often not practical. In situ monitoring of performance is desirable and can be done with built-in reference standards based on melting or freezing phase transitions. Binary alloys with a monotectic reaction frequently have two invariant melt/freeze phase transitions taking place in the same material over a range of compositions. This makes them potentially well suited to be in situ temperature calibration artifacts, enabling correction for thermocouple drift without the need to disturb the thermocouple. A zinc-bismuth fixed-point cell was constructed and has been shown to be stable with two well-defined melting plateaus at nominally 255°C and 415°C. Two miniature fixed-point cells (each designed to be permanently installed with a thermocouple) based on zinc-bismuth and aluminum-indium alloys were made. Measurements have shown that the phase transitions can be identified despite the small quantity of metals used and that the alloys were sufficiently stable to have the potential to provide improved long-term confidence in process control and monitoring.

  10. Aluminum Fixed Point: Impact of the Time Spent in the Liquid Phase on the Liquid-Solid Transition and Obviousness of the Pollution of the Ingot

    NASA Astrophysics Data System (ADS)

    Renaot, E.; Martin, C.

    2011-08-01

    In order to improve the uncertainty on the aluminum fixed point, a study was launched by Laboratoire Commun de Métrologie LNE-CNAM in the frame of the EURAMET Project 732 "Toward more accurate temperature fixed points" (coordinating laboratory: France, 17 partner countries). An earlier study completed in this laboratory showed that in regular realization of the melting-freezing plateaus, there is no diffusion of impurities in the thickness of the ingot, or the diffusion is excessively slow and cannot allow a uniform distribution of the impurities. On the other hand, it is frequently noticed that the experimental conditions before the freezing plateau have an impact on its characteristics (value, slope,…). Up to now, no systematic study was performed on the influence of this parameter. So, the objective of the task started recently in this laboratory is to investigate the influence of the time spent in the liquid phase on the phase transition. As a final result, it is demonstrated that in order to reach the equilibrium of the concentration of impurities, it is necessary to ensure that the metal remains in the liquid phase at least 24 h before initiating the freeze. At the end of the process, the aluminum ingot was chemically analyzed. The analyses reveal large contaminations of the surface of the ingot (sodium, sulfur, and phosphorus). One of the important outputs of this study is that the conditions of usage of the cells should be given important attention since large contaminations can be brought by the furnace.

  11. Infrared quasi-fixed-point structure in extended Yukawa sectors and application to R-parity violation

    NASA Astrophysics Data System (ADS)

    Mambrini, Y.; Moultaka, G.

    2002-06-01

    We investigate the one-loop renormalization-group evolution of extended sectors of Yukawa-type couplings. It is shown that Landau poles, which usually provide the necessary low-energy upper bounds that saturate quickly with increasing initial value conditions, lead in some cases to the opposite behavior: some of the low-energy couplings decrease and become vanishingly small for increasingly large initial conditions. We write down the general criteria for this to happen in typical situations, highlighting a concept of repulsive quasifixed points, and illustrate the case both within a two-Yukawa toy model as well as in the minimal supersymmetric standard model with R-parity violation. In the latter case, we consider the theoretical upper bounds on the various couplings, identifying regimes where λkl3,λ'kkk,λ″3kl are dynamically suppressed due to the Landau pole. We stress the importance of considering a large number of couplings simultaneously. This leads altogether to a phenomenologically interesting seesaw effect in the magnitudes of the various R-parity violating couplings, complementing and in some cases improving the existing limits.

  12. Field-Enhanced Kondo Correlations in a Half-Filling Nanotube Dot: Evolution of an SU(N) Fermi-Liquid Fixed Point

    NASA Astrophysics Data System (ADS)

    Teratani, Yoshimichi; Sakano, Rui; Fujiwara, Ryo; Hata, Tokuro; Arakawa, Tomonori; Ferrier, Meydi; Kobayashi, Kensuke; Oguri, Akira

    2016-09-01

    Carbon nanotube quantum dot has four-fold degenerate one-particle levels, which bring a variety to the Kondo effects taking place in a wide tunable-parameter space. We theoretically study an emergent SU(2) symmetry that is suggested by recent magneto-transport measurements, carried out near two electrons filling. It does not couple with the magnetic field, and emerges in the case where the spin and orbital Zeeman splittings cancel each other out in two of the one-particle levels among four. This situation seems to be realized in the recent experiment. Using the Wilson numerical renormalization group, we show that a crossover from the SU(4) to SU(2) Fermi-liquid behavior occurs as magnetic field increases at two impurity-electrons filling. We also find that the quasiparticles are significantly renormalized as the remaining two one-particle levels move away from the Fermi level and are frozen at high magnetic fields. Furthermore, we consider how the singlet ground state evolves during such a crossover. Specifically, we reexamine the SU(N) Kondo singlet for M impurity-electrons filling in the limit of strong exchange interactions. We find that the nondegenerate Fermi-liquid fixed point of Nozières and Blandin can be described as abosonic Perron-Frobenius vector for M composite pairs, each of which consists of one impurity-electron and one conduction-hole. This interpretation in terms of the Perron-Frobenius theorem can also be extended to the Fermi-liquid fixed-point without the SU(N) symmetry.

  13. Tightly Coupled Integration of GPS Ambiguity Fixed Precise Point Positioning and MEMS-INS through a Troposphere-Constrained Adaptive Kalman Filter

    PubMed Central

    Han, Houzeng; Xu, Tianhe; Wang, Jian

    2016-01-01

    Precise Point Positioning (PPP) makes use of the undifferenced pseudorange and carrier phase measurements with ionospheric-free (IF) combinations to achieve centimeter-level positioning accuracy. Conventionally, the IF ambiguities are estimated as float values. To improve the PPP positioning accuracy and shorten the convergence time, the integer phase clock model with between-satellites single-difference (BSSD) operation is used to recover the integer property. However, the continuity and availability of stand-alone PPP is largely restricted by the observation environment. The positioning performance will be significantly degraded when GPS operates under challenging environments, if less than five satellites are present. A commonly used approach is integrating a low cost inertial sensor to improve the positioning performance and robustness. In this study, a tightly coupled (TC) algorithm is implemented by integrating PPP with inertial navigation system (INS) using an Extended Kalman filter (EKF). The navigation states, inertial sensor errors and GPS error states are estimated together. The troposphere constrained approach, which utilizes external tropospheric delay as virtual observation, is applied to further improve the ambiguity-fixed height positioning accuracy, and an improved adaptive filtering strategy is implemented to improve the covariance modelling considering the realistic noise effect. A field vehicular test with a geodetic GPS receiver and a low cost inertial sensor was conducted to validate the improvement on positioning performance with the proposed approach. The results show that the positioning accuracy has been improved with inertial aiding. Centimeter-level positioning accuracy is achievable during the test, and the PPP/INS TC integration achieves a fast re-convergence after signal outages. For troposphere constrained solutions, a significant improvement for the height component has been obtained. The overall positioning accuracies of the height

  14. Tightly Coupled Integration of GPS Ambiguity Fixed Precise Point Positioning and MEMS-INS through a Troposphere-Constrained Adaptive Kalman Filter.

    PubMed

    Han, Houzeng; Xu, Tianhe; Wang, Jian

    2016-01-01

    Precise Point Positioning (PPP) makes use of the undifferenced pseudorange and carrier phase measurements with ionospheric-free (IF) combinations to achieve centimeter-level positioning accuracy. Conventionally, the IF ambiguities are estimated as float values. To improve the PPP positioning accuracy and shorten the convergence time, the integer phase clock model with between-satellites single-difference (BSSD) operation is used to recover the integer property. However, the continuity and availability of stand-alone PPP is largely restricted by the observation environment. The positioning performance will be significantly degraded when GPS operates under challenging environments, if less than five satellites are present. A commonly used approach is integrating a low cost inertial sensor to improve the positioning performance and robustness. In this study, a tightly coupled (TC) algorithm is implemented by integrating PPP with inertial navigation system (INS) using an Extended Kalman filter (EKF). The navigation states, inertial sensor errors and GPS error states are estimated together. The troposphere constrained approach, which utilizes external tropospheric delay as virtual observation, is applied to further improve the ambiguity-fixed height positioning accuracy, and an improved adaptive filtering strategy is implemented to improve the covariance modelling considering the realistic noise effect. A field vehicular test with a geodetic GPS receiver and a low cost inertial sensor was conducted to validate the improvement on positioning performance with the proposed approach. The results show that the positioning accuracy has been improved with inertial aiding. Centimeter-level positioning accuracy is achievable during the test, and the PPP/INS TC integration achieves a fast re-convergence after signal outages. For troposphere constrained solutions, a significant improvement for the height component has been obtained. The overall positioning accuracies of the height

  15. Tightly Coupled Integration of GPS Ambiguity Fixed Precise Point Positioning and MEMS-INS through a Troposphere-Constrained Adaptive Kalman Filter.

    PubMed

    Han, Houzeng; Xu, Tianhe; Wang, Jian

    2016-07-08

    Precise Point Positioning (PPP) makes use of the undifferenced pseudorange and carrier phase measurements with ionospheric-free (IF) combinations to achieve centimeter-level positioning accuracy. Conventionally, the IF ambiguities are estimated as float values. To improve the PPP positioning accuracy and shorten the convergence time, the integer phase clock model with between-satellites single-difference (BSSD) operation is used to recover the integer property. However, the continuity and availability of stand-alone PPP is largely restricted by the observation environment. The positioning performance will be significantly degraded when GPS operates under challenging environments, if less than five satellites are present. A commonly used approach is integrating a low cost inertial sensor to improve the positioning performance and robustness. In this study, a tightly coupled (TC) algorithm is implemented by integrating PPP with inertial navigation system (INS) using an Extended Kalman filter (EKF). The navigation states, inertial sensor errors and GPS error states are estimated together. The troposphere constrained approach, which utilizes external tropospheric delay as virtual observation, is applied to further improve the ambiguity-fixed height positioning accuracy, and an improved adaptive filtering strategy is implemented to improve the covariance modelling considering the realistic noise effect. A field vehicular test with a geodetic GPS receiver and a low cost inertial sensor was conducted to validate the improvement on positioning performance with the proposed approach. The results show that the positioning accuracy has been improved with inertial aiding. Centimeter-level positioning accuracy is achievable during the test, and the PPP/INS TC integration achieves a fast re-convergence after signal outages. For troposphere constrained solutions, a significant improvement for the height component has been obtained. The overall positioning accuracies of the height

  16. Fixed-point observation of mixed layer evolution in seasonally ice-free Chukchi Sea: Turbulent mixing due to gale winds and internal gravity waves

    NASA Astrophysics Data System (ADS)

    Kawaguchi, Y.; Inoue, J.; Nishino, S.

    2015-12-01

    A fixed-point observation using the R/V Mirai was conducted in the ice-free northern Chukchi Sea of the Arctic Ocean during September of 2013. During the program the authors performed repeated microstructure measurements to reveal the temporal evolution of the surface mixed layer and mixing processes in the upper water column. The shelf region was initially characterized by a distinct two-layer system comprising a warmer/ fresher top layer and a colder/saltier bottom layer. During the two-week observation period, the top-layer water showed two types of mixing processes: near-surface turbulence due to strong wind forcing and subsurface mixing due to internal gravity waves. In the first week, when the top layer was stratified with fresh sea ice meltwater, turbulent energy related to internal waves propagated through the subsurface stratification, resulting in a mechanical overturning near the pycnocline, followed by enhanced mixing there. In the second week, gale winds directly stirred up the upper water and then established a deeper homogenous layer. The combination of internal wave mixing and wind-driven turbulence may contribute to releasing the oceanic heat into the atmosphere, consequently promoting the preconditioning of surface water freezing.

  17. Performance of Pt-C, CrC-CrC, CrC-C, and Ru-C Fixed Points for Thermocouple Calibrations Above 1600 C

    NASA Astrophysics Data System (ADS)

    Pearce, J. V.; Elliott, C. J.; Lowe, D. H.; Failleau, G.; Deuzé, T.; Bourson, F.; Sadli, M.; Machin, G.

    2014-04-01

    A series of high-temperature fixed points (HTFPs) Pt-C (1738 , and Ru-C (1953 ) have been constructed at the National Physical Laboratory (NPL) and the Laboratoire National de métrologie et d'Essais and Conservatoire national des arts et métiers (LNE-Cnam). These are required for the calibration of high-temperature thermocouples in the framework of work package 6 of the European Metrology Research Programme IND01 project "HiTeMS." The goal of this work package is to establish a European capability that can determine low-uncertainty reference functions of non-standard high-temperature thermocouples. For reference functions to be widely applicable, measurements must be performed by more than one institute and preferably by more than one method. Due to the high price of the ingot materials, miniature HTFP cells are used. NPL and LNE-Cnam constructed their HTFP cells with different designs; these are described here, together with the performance of the cells using both radiation thermometry and thermocouples. The melting temperature of the Ru-C cells (for thermocouple calibrations) was determined using radiation thermometry at both NPL and LNE-Cnam, and the two results are compared. The suitability of the cells for calibration of W-Re and Rh-Ir thermocouples is evaluated, and some results are presented. Some discussion is given regarding the materials challenges when calibrating Rh-Ir thermocouples up to 2000 C.

  18. Influences of diurnal sampling bias on fixed-point monitoring of plankton biodiversity determined using a massively parallel sequencing-based technique.

    PubMed

    Nagai, Satoshi; Hida, Kohsuke; Urushizaki, Shingo; Onitsuka, Goh; Yasuike, Motoshige; Nakamura, Yoji; Fujiwara, Atushi; Tajimi, Seisuke; Kimoto, Katsunori; Kobayashi, Takanori; Gojobori, Takashi; Ototake, Mitsuru

    2016-02-01

    In this study, we investigated the influence of diurnal sampling bias on the community structure of plankton by comparing the biodiversity among seawater samples (n=9) obtained every 3h for 24h by using massively parallel sequencing (MPS)-based plankton monitoring at a fixed point conducted at Himedo seaport in Yatsushiro Sea, Japan. The number of raw operational taxonomy units (OTUs) and OTUs after re-sampling was 507-658 (558 ± 104, mean ± standard deviation) and 448-544 (467 ± 81), respectively, indicating high plankton biodiversity at the sampling location. The relative abundance of the top 20 OTUs in the samples from Himedo seaport was 48.8-67.7% (58.0 ± 5.8%), and the highest-ranked OTU was Pseudo-nitzschia species (Bacillariophyta) with a relative abundance of 17.3-39.2%, followed by Oithona sp. 1 and Oithona sp. 2 (Arthropoda). During seawater sampling, the semidiurnal tidal current having an amplitude of 0.3ms(-1) was dominant, and the westward residual current driven by the northeasterly wind was continuously observed during the 24-h monitoring. Therefore, the relative abundance of plankton species apparently fluctuated among the samples, but no significant difference was noted according to G-test (p>0.05). Significant differences were observed between the samples obtained from a different locality (Kusuura in Yatsushiro Sea) and at different dates, suggesting that the influence of diurnal sampling bias on plankton diversity, determined using the MPS-based survey, was not significant and acceptable.

  19. Carbonate chemistry and air-sea CO2 flux at a fixed point in a NW Mediterranean Bay, Villefranche-sur-Mer, France

    NASA Astrophysics Data System (ADS)

    De Carlo, E. H.; Mousseau, L.; Passafiume, O.; Drupp, P. S.; Gattuso, J.

    2011-12-01

    The purpose of the Service d'Observation de la Rade de Villefranche-sur-Mer (SO-RADE) is to study the temporal variability of hydrological conditions as well as the abundance and composition of holo- and meroplankton at a fixed station in the bay of Villefranche-sur-Mer, North West Mediterranean. The weekly data collected at this site, designated as "Point B (43° 41.10'N - 7° 18.94'E), since 1957 are recognized as a long-term time series describing the evolution of the hydrological conditions in a coastal environment. Since 2007, historical measurements of hydrological and biological conditions have been complemented by measurements of the CO2-carbonate system parameters. In this contribution we present CO2-carbonate system parameters and ancillary data for the period 2007-2010. The data are evaluated in the context of the physical and biogeochemical processes that contribute to the fluxes of CO2 between the ocean and atmosphere. Seasonal cycles of seawater pCO2 are controlled principally by variations in temperature, showing maxima in the summer and minima during the winters. Normalization of pCO2 to the mean seawater temperature (18oC) results in an apparent reversal of the seasonal cycle with maxima observed in the winters and minima in the summers, consistent with a control of pCO2 by primary productivity. Calculations of "instantaneous fluxes" of CO2 between the ocean and atmosphere show this area to be primarily a weak source of CO2 to the atmosphere during the summer and a weak sink during the winter and near neutral overall (range: -0.3 to +0.3 mmol CO2 m-2 h-1, average: 0.02 mmol CO2 m-2 h-1). We will also provide projections of errors incurred from the estimation of annualized fluxes of CO2 based on weekly measurements relative to daily and high-frequency (3 h) data such as those obtained at the Hawaii Kilo Nalu coastal time series station, which shows similar behavior to the Point B location despite significant differences in climate and hydrological

  20. NASA's SDO Sees Unraveling Solar Prominence

    NASA Video Gallery

    An elongated solar prominence rose up above the sun’s surface and slowly unraveled on Feb. 3, 2016, as seen in this video by NASA’s Solar Dynamics Observatory, or SDO. The sun appears to move in th...

  1. Research and operational products from the combination of a monthly hydrographic station and an oceanic buoy: The Biscay AGL fixed-point water column observatory.

    NASA Astrophysics Data System (ADS)

    Lavin, Alicia; Cano, Daniel; González-Pola, Cesar; Tel, Elena; Rodriguez, Carmen; Ruiz, Manuel; Somavilla, Raquel

    2015-04-01

    , but Dissolved Oxygen sensor is also problematic. Periods of realistic smooth variations present strong offset that is corrected based on the Winkler analysis of water samples. The incorporation of these observatories on larger scale research programs, as done in 2003 in the framework of the VACLAN and COVACLAN projects, is important in order to provide them with a larger spatial dimension and maximize its utility for process-oriented studies. In 2003, the Santander section was extended 90 miles offshore in the framework of a large-scale hydrographic and circulation monitoring program. Partnerships in a large EU project as FixO3 has provided tools for coordination, homogenization and data validation as well as improve the use of chemical-biological data.

  2. Primitive models of chemical association. III. Totally flexible sticky two-point model for multicomponent heteronuclear fixed-chain-length polymerization

    SciTech Connect

    Lin, C.; Kalyuzhnyi, Y.V. |; Stell, G.

    1998-04-01

    A multidensity integral-equation theory for polymerization into freely jointed hard-sphere homonuclear chain fluids proposed earlier [J. Chem. Phys. {bold 106}, 1940 (1997)] is extended to the case of multicomponent heteronuclear chain polymerization. The theory is based on the analytical solution of the polymer Percus{endash}Yevick (PPY) approximation for the totally flexible sticky two-point (S2P) model of associating fluids. The model consists of an n-component mixture of hard spheres of different sizes with species 2,{hor_ellipsis},n{minus}1 bearing two sticky sites A and B, randomly distributed on its surface, and species 1 and n with only one B and A site per particle, respectively. Due to some specific restrictions imposed on the possibility of forming bonds between particles of various species, the present version of the S2P model represents an associating fluid that is able to polymerize into a mixture of heteronuclear chain macromolecules. The structural properties of such a model are studied in the complete-association limit and compared with computer-simulation results for homonuclear hard-sphere chain mixtures, symmetrical diblock copolymers, alternating copolymers, and homonuclear hard-sphere chains in a hard-sphere solvent. Some results for the case of partial association are also presented. The PPY theory represents a quantitatively successful theory for the mixtures of short homonuclear chains and the short copolymer systems studied here. We also expect that the theory will prove to be of the same order of accuracy in investigating the case of partial association. {copyright} {ital 1998 American Institute of Physics.}

  3. Doing Class Analysis in Singapore's Elite Education: Unravelling the Smokescreen of "Meritocratic Talk"

    ERIC Educational Resources Information Center

    Koh, Aaron

    2014-01-01

    This paper examines the specificity of the education-class nexus in an elite independent school in Singapore. It seeks to unravel the puzzle that meritocracy is dogmatically believed in Singapore in spite of evidences that point to the contrary. The paper draws on discursive (analysis of media materials) and institutional (analysis of interview…

  4. Unraveling the riddle of syringomyelia.

    PubMed

    Greitz, Dan

    2006-10-01

    The pathophysiology of syringomyelia development is not fully understood. Current prevailing theories suggest that increased pulse pressure in the subarachnoid space forces cerebrospinal fluid (CSF) through the spinal cord into the syrinx. It is generally accepted that the syrinx consists of CSF. The here-proposed intramedullary pulse pressure theory instead suggests that syringomyelia is caused by increased pulse pressure in the spinal cord and that the syrinx consists of extracellular fluid. A new principle is introduced implying that the distending force in the production of syringomyelia is a relative increase in pulse pressure in the spinal cord compared to that in the nearby subarachnoid space. The formation of a syrinx then occurs by the accumulation of extracellular fluid in the distended cord. A previously unrecognized mechanism for syrinx formation, the Bernoulli theorem, is also described. The Bernoulli theorem or the Venturi effect states that the regional increase in fluid velocity in a narrowed flow channel decreases fluid pressure. In Chiari I malformations, the systolic CSF pulse pressure and downward motion of the cerebellar tonsils are significantly increased. This leads to increased spinal CSF velocities and, as a consequence of the Bernoulli theorem, decreased fluid pressure in narrow regions of the spinal CSF pathways. The resulting relatively low CSF pressure in the narrowed CSF pathway causes a suction effect on the spinal cord that distends the cord during each systole. Syringomyelia develops by the accumulation of extracellular fluid in the distended cord. In posttraumatic syringomyelia, the downwards directed systolic CSF pulse pressure is transmitted and reflected into the spinal cord below and above the traumatic subarachnoid blockage, respectively. The ensuing increase in intramedullary pulse pressure distends the spinal cord and causes syringomyelia on both sides of the blockage. The here-proposed concept has the potential to unravel

  5. Fixed memory least squares filtering

    NASA Technical Reports Server (NTRS)

    Bierman, G. J.

    1975-01-01

    Buxbaum has reported on three algorithms for computing least squares estimates that are based on fixed amounts of data. In this correspondence, the filter is arranged as a point-deleting Kalman filter concatenated with the standard point-inclusion Kalman filter. The resulting algorithm is couched in a square root framework for greater numerical stability, and special attention is given to computer implementation.

  6. Alarm points for fixed oxygen monitors

    SciTech Connect

    Miller, G.C.

    1987-05-01

    Oxygen concentration monitors were installed in a vault where numerous pipes carried inert cryogens and gases to the Mirror Fusion Test Facility (MFTF-B) experimental vessel at Lawrence Livermore National Laboratory (LLNL). The problems associated with oxygen-monitoring systems and the reasons why such monitors were installed were reviewed. As a result of this review, the MFTF-B monitors were set to sound an evacuation alarm when the oxygen concentration fell below 18%. We chose the 18% alarm criterion to minimize false alarms and to allow time for personnel to escape in an oxygen-deficient environment.

  7. Algorithmic-Reducibility = Renormalization-Group Fixed-Points; ``Noise''-Induced Phase-Transitions (NITs) to Accelerate Algorithmics (``NIT-Picking'') Replacing CRUTCHES!!!: Gauss Modular/Clock-Arithmetic Congruences = Signal X Noise PRODUCTS..

    NASA Astrophysics Data System (ADS)

    Siegel, J.; Siegel, Edward Carl-Ludwig

    2011-03-01

    Cook-Levin computational-"complexity"(C-C) algorithmic-equivalence reduction-theorem reducibility equivalence to renormalization-(semi)-group phase-transitions critical-phenomena statistical-physics universality-classes fixed-points, is exploited with Gauss modular/clock-arithmetic/model congruences = signal X noise PRODUCT reinterpretation. Siegel-Baez FUZZYICS=CATEGORYICS(SON of ``TRIZ''): Category-Semantics(C-S) tabular list-format truth-table matrix analytics predicts and implements "noise"-induced phase-transitions (NITs) to accelerate versus to decelerate Harel [Algorithmics(1987)]-Sipser[Intro. Theory Computation(1997) algorithmic C-C: "NIT-picking" to optimize optimization-problems optimally(OOPO). Versus iso-"noise" power-spectrum quantitative-only amplitude/magnitude-only variation stochastic-resonance, this "NIT-picking" is "noise" power-spectrum QUALitative-type variation via quantitative critical-exponents variation. Computer-"science" algorithmic C-C models: Turing-machine, finite-state-models/automata, are identified as early-days once-workable but NOW ONLY LIMITING CRUTCHES IMPEDING latter-days new-insights!!!

  8. Unraveling photosystems. Final technical report

    SciTech Connect

    1997-09-01

    This report highlights four main points. (1) A residue substitution in phosphoribulokinase of Synechocystis PCC 6803 renders the mutant light-sensitive. The authors isolated a light-sensitive mutant (BRLS) of the photosynthetic cyanobacterium Synechocystis 6803 that does not survive exposure to bright light; 70% of BRLS cells die upon exposure to light of > 3000 lux for 2 hr. (2) Excitation energy transfer from phycocyanin to chlorophyll in an apcA-defective mutant of Synechocystis sp. PCC 6803. A greenish mutant of the normally bule-green cyanobacterium Synechocystis sp. PC 6803, designated UV6p, was isolated and characterized. UV6p possesses functional photosystems I and II but lacks normal light harvesting phycobilisomes because allophycocyanin is absent and core-specific linker proteins are almost entirely absent. (3) Deletion of the psbG1 gene of the cyanobacterium Synechocystis sp. PCC 6803 leads to the activation of the cryptic psbG2 gene. The genes psbG1 and psbG2 in cyanobacterium Synechocystis sp. PCC 6803 are homologous. The psbG1 gene is located on the chromosome and is part of the ndhC-psbG1-ORF157 operon, while psbG2 is located on a plasmid and is not flanked by equivalent ndhC or ORF157 genes. (4) Deletion of the structural gene for the NADH-dehydrogenase subunit 4 of Synechocystis 6803 alters respiratory properties. Chloroplasts and cyanobacteria contain genes encoding polypeptides homologous to some subunits of the mitochondrial respiratory NADH-ubiquinol oxidoreductase complex (NADH dehydrogenase). Nothing is known of the role of the NADH dehydrogenase complex in photosynthesis, respiration, or other functions in chloroplasts, and little is known about their specific roles in the perhaps 42 subunits of this complex in the mitochondrion.

  9. Full and partial gauge fixing

    SciTech Connect

    Shirzad, A.

    2007-08-15

    Gauge fixing may be done in different ways. We show that using the chain structure to describe a constrained system enables us to use either a full gauge, in which all gauged degrees of freedom are determined, or a partial gauge, in which some first class constraints remain as subsidiary conditions to be imposed on the solutions of the equations of motion. We also show that the number of constants of motion depends on the level in a constraint chain in which the gauge fixing condition is imposed. The relativistic point particle, electromagnetism, and the Polyakov string are discussed as examples and full or partial gauges are distinguished.

  10. Jump-diffusion unravelling of a non-Markovian generalized Lindblad master equation

    SciTech Connect

    Barchielli, A.; Pellegrini, C.

    2010-11-15

    The ''correlated-projection technique'' has been successfully applied to derive a large class of highly non-Markovian dynamics, the so called non-Markovian generalized Lindblad-type equations or Lindblad rate equations. In this article, general unravelings are presented for these equations, described in terms of jump-diffusion stochastic differential equations for wave functions. We show also that the proposed unraveling can be interpreted in terms of measurements continuous in time but with some conceptual restrictions. The main point in the measurement interpretation is that the structure itself of the underlying mathematical theory poses restrictions on what can be considered as observable and what is not; such restrictions can be seen as the effect of some kind of superselection rule. Finally, we develop a concrete example and discuss possible effects on the heterodyne spectrum of a two-level system due to a structured thermal-like bath with memory.

  11. Unraveling the Miswired Connectome: A Developmental Perspective

    PubMed Central

    Di Martino, Adriana; Fair, Damien A.; Kelly, Clare; Satterthwaite, Theodore D.; Castellanos, F. Xavier; Thomason, Moriah E.; Craddock, R. Cameron; Luna, Beatriz; Leventhal, Bennett L.; Zuo, Xi-Nian; Milham, Michael P.

    2014-01-01

    Summary The vast majority of mental illnesses can be conceptualized as developmental disorders of neural interactions within the connectome, or developmental miswiring. The recent maturation of pediatric in vivo brain imaging is bringing within reach the identification of clinically meaningful brain-based biomarkers of developmental disorders. Even more auspicious, is the ability to study the evolving connectome throughout life, beginning in utero, which promises to move the field from topological phenomenology to etiological nosology. Here, we scope advances in pediatric imaging of the brain connectome as the field faces the challenge of unraveling developmental miswiring. We highlight promises while also providing a pragmatic review of the many obstacles ahead that must be overcome to significantly impact public health. PMID:25233316

  12. 30 CFR 56.11026 - Protection for inclined fixed ladders.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Protection for inclined fixed ladders. 56.11026... § 56.11026 Protection for inclined fixed ladders. Fixed ladders 70 degrees to 90 degrees from the... point not more than seven feet from the bottom of the ladders....

  13. 30 CFR 56.11026 - Protection for inclined fixed ladders.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Protection for inclined fixed ladders. 56.11026... § 56.11026 Protection for inclined fixed ladders. Fixed ladders 70 degrees to 90 degrees from the... point not more than seven feet from the bottom of the ladders....

  14. Geometric phase for open quantum systems and stochastic unravelings

    SciTech Connect

    Bassi, Angelo; Ippoliti, Emiliano

    2006-06-15

    We analyze the geometric phase for an open quantum system when computed by resorting to a stochastic unraveling of the reduced density matrix (quantum jump approach or stochastic Schroedinger equations). We show that the resulting phase strongly depends on the type of unraveling used for the calculations: as such, this phase is not a geometric object since it depends on nonphysical parameters, which are not related to the path followed by the density matrix during the evolution of the system.

  15. Unraveling the complex metabolic nature of astrocytes.

    PubMed

    Bouzier-Sore, Anne-Karine; Pellerin, Luc

    2013-01-01

    Since the initial description of astrocytes by neuroanatomists of the nineteenth century, a critical metabolic role for these cells has been suggested in the central nervous system. Nonetheless, it took several technological and conceptual advances over many years before we could start to understand how they fulfill such a role. One of the important and early recognized metabolic function of astrocytes concerns the reuptake and recycling of the neurotransmitter glutamate. But the description of this initial property will be followed by several others including an implication in the supply of energetic substrates to neurons. Indeed, despite the fact that like most eukaryotic non-proliferative cells, astrocytes rely on oxidative metabolism for energy production, they exhibit a prominent aerobic glycolysis capacity. Moreover, this unusual metabolic feature was found to be modulated by glutamatergic activity constituting the initial step of the neurometabolic coupling mechanism. Several approaches, including biochemical measurements in cultured cells, genetic screening, dynamic cell imaging, nuclear magnetic resonance spectroscopy and mathematical modeling, have provided further insights into the intrinsic characteristics giving rise to these key features of astrocytes. This review will provide an account of the different results obtained over several decades that contributed to unravel the complex metabolic nature of astrocytes that make this cell type unique.

  16. Unraveling the complex metabolic nature of astrocytes

    PubMed Central

    Bouzier-Sore, Anne-Karine; Pellerin, Luc

    2013-01-01

    Since the initial description of astrocytes by neuroanatomists of the nineteenth century, a critical metabolic role for these cells has been suggested in the central nervous system. Nonetheless, it took several technological and conceptual advances over many years before we could start to understand how they fulfill such a role. One of the important and early recognized metabolic function of astrocytes concerns the reuptake and recycling of the neurotransmitter glutamate. But the description of this initial property will be followed by several others including an implication in the supply of energetic substrates to neurons. Indeed, despite the fact that like most eukaryotic non-proliferative cells, astrocytes rely on oxidative metabolism for energy production, they exhibit a prominent aerobic glycolysis capacity. Moreover, this unusual metabolic feature was found to be modulated by glutamatergic activity constituting the initial step of the neurometabolic coupling mechanism. Several approaches, including biochemical measurements in cultured cells, genetic screening, dynamic cell imaging, nuclear magnetic resonance spectroscopy and mathematical modeling, have provided further insights into the intrinsic characteristics giving rise to these key features of astrocytes. This review will provide an account of the different results obtained over several decades that contributed to unravel the complex metabolic nature of astrocytes that make this cell type unique. PMID:24130515

  17. Finite volume QCD at fixed topological charge

    SciTech Connect

    Aoki, Sinya; Fukaya, Hidenori; Hashimoto, Shoji; Onogi, Tetsuya

    2007-09-01

    In finite volume the partition function of QCD with a given {theta} is a sum of different topological sectors with a weight primarily determined by the topological susceptibility. If a physical observable is evaluated only in a fixed topological sector, the result deviates from the true expectation value by an amount proportional to the inverse space-time volume 1/V. Using the saddle point expansion, we derive formulas to express the correction due to the fixed topological charge in terms of a 1/V expansion. Applying this formula, we propose a class of methods to determine the topological susceptibility in QCD from various correlation functions calculated in a fixed topological sector.

  18. Unraveling Researcher Subjectivity through Multivocality in Autoethnography

    ERIC Educational Resources Information Center

    Mizzi, Robert

    2010-01-01

    This article analyzes and discusses the notion of including multivocality as an autoethnographic method to: (a) illustrate that there is no single and temporally-fixed voice that a researcher possesses, (b) unfix identity in a way that exposes the fluid nature of identity as it moves through particular contexts, and (c) deconstruct competing…

  19. [Advantages of fixed combinations].

    PubMed

    Lachkar, Y

    2008-07-01

    Fixed combinations are indicated in the treatment of glaucoma and ocular hypertension when monotherapy does not sufficiently reduce IOP. Fixed combinations show better efficacy than the instillation of each separate component and are at least equivalent to the administration of both components in a separate association. They simplify treatment, increase compliance and quality of life, and decrease exposure to preservatives. Although they are less aggressive for patients when a new drug needs to be added, the use of fixed combinations should not decrease the follow-up. PMID:18957922

  20. Fixed Exit Monochromator with fixed Rotation Axis

    SciTech Connect

    Caliebe, W.A.; Cheung, S.; Lenhard, A.; Siddons, D.P.

    2004-05-12

    A new simple design for a fixed-exit monochromator has been developed. The set-up uses a linear slide to couple the rotation of the crystals to a translation of the second one to compensate for the 2hcos{theta} dependence of the beam-offset in a double crystal monochromator. This set-up requires just one motor for the rotation of the monochromator, and three piezo-actuators to tune the second crystal.The monochromator has been tested for Bragg-angles between 7 deg. and 70 deg.

  1. Unravelling the chemical characteristics of YSOs

    NASA Astrophysics Data System (ADS)

    van Dishoeck, Ewine F.

    1999-10-01

    The formation of stars is accompanied by orders of magnitude changes in the physical conditions, with densities in the envelopes and disks increasing from 104 cm-3 to > 1013 cm-3 and temperatures from ~ 10 K in the cold quiescent gas to 10,000 K in shocked regions. The abundances and excitation of the various molecules respond to these changes, and are therefore excellent probes of the physical evolution of YSOs. Moreover, a comprehensive inventory of the chemical composition of envelopes and disks at different evolutionary stages is essential to study the chemistry of matter as it is incorporated into new solar systems. Recent observations of the envelopes of YSOs using single-dish telescopes and millimeter interferometers clearly reveal the potential of submillimeter lines to probe these physical and chemical changes. However, the existing data generally lack the spatial resolution to separate the different physical components, such as the warm inner envelope or `hot core', the region of interaction of the outflow with the envelope and any possible circumstellar disk. ALMA will be essential to provide an `unblurred' view of the YSO environment and unravel the chemical evolution during star formation. In this talk, an overview will be given of recent single-dish and interferometer results of the chemistry in the envelopes and disks around low- and high-mass young stellar objects. Together with ISO data on solid-state material, these observations lead to a chemical scenario in which both gas-phase and gas-grain chemistry (in particular freeze-out and evaporation) play an important role. The evaporated molecules drive a rich chemistry in the warm gas, which can result in complex organic molecules. The potential of ALMA to test chemical theories and determine the composition of gas and dust as it enters forming planetary systems will be illustrated.

  2. Fixing Dataset Search

    NASA Technical Reports Server (NTRS)

    Lynnes, Chris

    2014-01-01

    Three current search engines are queried for ozone data at the GES DISC. The results range from sub-optimal to counter-intuitive. We propose a method to fix dataset search by implementing a robust relevancy ranking scheme. The relevancy ranking scheme is based on several heuristics culled from more than 20 years of helping users select datasets.

  3. Fixed mount wavefront sensor

    DOEpatents

    Neal, Daniel R.

    2000-01-01

    A rigid mount and method of mounting for a wavefront sensor. A wavefront dissector, such as a lenslet array, is rigidly mounted at a fixed distance relative to an imager, such as a CCD camera, without need for a relay imaging lens therebetween.

  4. Unraveling "Braid": Puzzle Games and Storytelling in the Imperative Mood

    ERIC Educational Resources Information Center

    Arnott, Luke

    2012-01-01

    "Unraveling Braid" analyzes how unconventional, non-linear narrative fiction can help explain the ways in which video games signify. Specifically, this essay looks at the links between the semiotic features of Jonathan Blow's 2008 puzzle-platform video game Braid and similar elements in Georges Perec's 1978 novel "Life A User's Manual," as well as…

  5. Unraveling of a detailed-balance-preserved quantum master equation and continuous feedback control of a measured qubit

    NASA Astrophysics Data System (ADS)

    Luo, JunYan; Jin, Jinshuang; Wang, Shi-Kuan; Hu, Jing; Huang, Yixiao; He, Xiao-Ling

    2016-03-01

    We present a generic unraveling scheme for a detailed-balance-preserved quantum master equation applicable for stochastic point processes in mesoscopic transport. It enables us to investigate continuous measurement of a qubit on the level of single quantum trajectories, where essential correlations between the inherent dynamics of the qubit and detector current fluctuations are revealed. Based on this unraveling scheme, feedback control of the charge qubit is implemented to achieve a desired pure state in the presence of the detailed-balance condition. With sufficient feedback strength, coherent oscillations of the measured qubit can be maintained for arbitrary qubit-detector coupling. Competition between the loss and restoration of coherence entailed, respectively, by measurement back action and feedback control is reflected in the noise power spectrum of the detector's output. It is demonstrated unambiguously that the signal-to-noise ratio is significantly enhanced with increasing feedback strength and could even exceed the well-known Korotkov-Averin bound in quantum measurement. The proposed unraveling and feedback scheme offers a transparent and straightforward approach to effectively sustaining ideal coherent oscillations of a charge qubit in the field of quantum computation.

  6. THE DYNAMICS OF CATEGORIZATION: UNRAVELING RAPID CATEGORIZATION

    PubMed Central

    Mack, Michael L.; Palmeri, Thomas J.

    2015-01-01

    We explore a puzzle of visual object categorization: Under normal viewing conditions, you spot something as a dog fastest, but at a glance, you spot it faster as an animal. During speeded category verification, a classic basic-level advantage is commonly observed (Rosch, Mervis, Gray, Johnson, & Boyes-Braem, 1976), with categorization as a dog faster than as an animal (superordinate) or Golden Retriever (subordinate). A different story emerges during ultra-rapid categorization with limited exposure duration (<30ms), with superordinate categorization faster than basic or subordinate categorization (Thorpe, Fize, & Marlot, 1996). These two widely cited findings paint contrary theoretical pictures about the time course of object categorization, yet no study has previously investigated them together. Over five experiments, we systematically examined two experimental factors that could explain the qualitative difference in categorization across the two paradigms: exposure duration and category trial context. Mapping out the time course of object categorization by manipulating exposure duration and the timing of a post-stimulus mask revealed that brief exposure durations favor superordinate-level categorization, but with more time a basic-level advantage emerges. But this superordinate advantage was modulated significantly by target category trial context. With randomized target categories, the superordinate advantage was eliminated; and with “blocks” of only four repetitions of superordinate categorization within an otherwise randomized context, the advantage for the basic-level was eliminated. Contrary to some theoretical accounts that dictate a fixed priority for certain levels of abstraction in visual processing and access to semantic knowledge, the dynamics of object categorization are flexible, depending jointly on the level of abstraction, time for perceptual encoding, and category context. PMID:25938178

  7. Fixed target facility at the SSC

    SciTech Connect

    Loken, S.C.; Morfin, J.G.

    1985-01-01

    The question of whether a facility for fixed target physics should be provided at the SSC must be answered before the final technical design of the SSC can be completed, particularly if the eventual form of extraction would influence the magnet design. To this end, an enthusiastic group of experimentalists, theoreticians and accelerator specialists have studied this point. The accelerator physics issues were addressed by a group led by E. Colton whose report is contained in these proceedings. The physics addressable by fixed target was considered by many of the Physics area working groups and in particular by the Structure Function Group. This report is the summary of the working group which considered various SSC fixed target experiments and determined which types of beams and detectors would be required. 13 references, 5 figures.

  8. 22. VIEW OF FIXED SPAN SUBSTRUCTURE, EAST SPAN, SHOWING CANTILEVEREDBEAM ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    22. VIEW OF FIXED SPAN SUBSTRUCTURE, EAST SPAN, SHOWING CANTILEVERED-BEAM SIDEWALK SUPPORTS, LONGITUDINAL GIRDER AND TRANSVERSE ROADBED BEAMS, LOOKING SOUTHEAST - Congress Street Bascule Bridge, Spanning Fort Point Channel at Congress Street, Boston, Suffolk County, MA

  9. Event parameters - fixed target

    SciTech Connect

    Poskanzer, A.; Ritter, H.G.; Ludewigt, B.; Foley, K.; Borenstein, S.; Platner, E.; Love, W.; Keane, D.; Plasil, F.

    1984-06-15

    This subgroup has focussed on detectors for fixed target experiments which have full azimuthal coverage. The general scope of the working group was to consider (1) the configuration of an idealized detector, and (2) various configurations of practical detectors that could be implemented on a relatively short time scale. The second category includes possible upgrades and modifications of existing experimental facilities. Beams of both 15 GeV/A sulphur at the AGS and 200 GeV/A oxygen at the SPS were considered.

  10. Unravelling emotional viewpoints on a bio-based economy using Q methodology.

    PubMed

    Sleenhoff, Susanne; Cuppen, Eefje; Osseweijer, Patricia

    2015-10-01

    A transition to a bio-based economy will affect society and requires collective action from a broad range of stakeholders. This includes the public, who are largely unaware of this transition. For meaningful public engagement people's emotional viewpoints play an important role. However, what the public's emotions about the transition are and how they can be taken into account is underexposed in public engagement literature and practice. This article aims to unravel the public's emotional views of the bio-based economy as a starting point for public engagement. Using Q methodology with visual representations of a bio-based economy we found four emotional viewpoints: (1) compassionate environmentalist, (2) principled optimist, (3) hopeful motorist and (4) cynical environmentalist. These provide insight into the distinct and shared ways through which members of the public connect with the transition. Implications for public engagement are discussed.

  11. Unraveling liver complexity from molecular to organ level: challenges and perspectives.

    PubMed

    D'Alessandro, L A; Hoehme, S; Henney, A; Drasdo, D; Klingmüller, U

    2015-01-01

    Biological responses are determined by information processing at multiple and highly interconnected scales. Within a tissue the individual cells respond to extracellular stimuli by regulating intracellular signaling pathways that in turn determine cell fate decisions and influence the behavior of neighboring cells. As a consequence the cellular responses critically impact tissue composition and architecture. Understanding the regulation of these mechanisms at different scales is key to unravel the emergent properties of biological systems. In this perspective, a multidisciplinary approach combining experimental data with mathematical modeling is introduced. We report the approach applied within the Virtual Liver Network to analyze processes that regulate liver functions from single cell responses to the organ level using a number of examples. By facilitating interdisciplinary collaborations, the Virtual Liver Network studies liver regeneration and inflammatory processes as well as liver metabolic functions at multiple scales, and thus provides a suitable example to identify challenges and point out potential future application of multi-scale systems biology.

  12. Unraveling liver complexity from molecular to organ level: challenges and perspectives.

    PubMed

    D'Alessandro, L A; Hoehme, S; Henney, A; Drasdo, D; Klingmüller, U

    2015-01-01

    Biological responses are determined by information processing at multiple and highly interconnected scales. Within a tissue the individual cells respond to extracellular stimuli by regulating intracellular signaling pathways that in turn determine cell fate decisions and influence the behavior of neighboring cells. As a consequence the cellular responses critically impact tissue composition and architecture. Understanding the regulation of these mechanisms at different scales is key to unravel the emergent properties of biological systems. In this perspective, a multidisciplinary approach combining experimental data with mathematical modeling is introduced. We report the approach applied within the Virtual Liver Network to analyze processes that regulate liver functions from single cell responses to the organ level using a number of examples. By facilitating interdisciplinary collaborations, the Virtual Liver Network studies liver regeneration and inflammatory processes as well as liver metabolic functions at multiple scales, and thus provides a suitable example to identify challenges and point out potential future application of multi-scale systems biology. PMID:25433231

  13. Unravelling emotional viewpoints on a bio-based economy using Q methodology.

    PubMed

    Sleenhoff, Susanne; Cuppen, Eefje; Osseweijer, Patricia

    2015-10-01

    A transition to a bio-based economy will affect society and requires collective action from a broad range of stakeholders. This includes the public, who are largely unaware of this transition. For meaningful public engagement people's emotional viewpoints play an important role. However, what the public's emotions about the transition are and how they can be taken into account is underexposed in public engagement literature and practice. This article aims to unravel the public's emotional views of the bio-based economy as a starting point for public engagement. Using Q methodology with visual representations of a bio-based economy we found four emotional viewpoints: (1) compassionate environmentalist, (2) principled optimist, (3) hopeful motorist and (4) cynical environmentalist. These provide insight into the distinct and shared ways through which members of the public connect with the transition. Implications for public engagement are discussed. PMID:24928568

  14. Fixed sagittal plane imbalance.

    PubMed

    Savage, Jason W; Patel, Alpesh A

    2014-12-01

    Study Design Literature review. Objective To discuss the evaluation and management of fixed sagittal plane imbalance. Methods A comprehensive literature review was performed on the preoperative evaluation of patients with sagittal plane malalignment, as well as the surgical strategies to address sagittal plane deformity. Results Sagittal plane imbalance is often caused by de novo scoliosis or iatrogenic flat back deformity. Understanding the etiology and magnitude of sagittal malalignment is crucial in realignment planning. Objective parameters have been developed to guide surgeons in determining how much correction is needed to achieve favorable outcomes. Currently, the goals of surgery are to restore a sagittal vertical axis < 5 cm, pelvic tilt < 20 degrees, and lumbar lordosis equal to pelvic incidence ± 9 degrees. Conclusion Sagittal plane malalignment is an increasingly recognized cause of pain and disability. Treatment of sagittal plane imbalance varies according to the etiology, location, and severity of the deformity. Fixed sagittal malalignment often requires complex reconstructive procedures that include osteotomy correction. Reestablishing harmonious spinopelvic alignment is associated with significant improvement in health-related quality-of-life outcome measures and patient satisfaction.

  15. Fixed and Sunk Costs Revisited.

    ERIC Educational Resources Information Center

    Wang, X. Henry; Yang, Bill Z.

    2001-01-01

    Attempts to clarify the concepts of, and the link between, fixed costs and sunk costs. Argues that the root of confusion is the inconsistency in defining the term fixed costs. Consistently defines fixed and sunk costs, and describes how instructors must teach under these definitions. (RLH)

  16. Soft Crystals in Flatland: Unraveling Epitaxial Growth.

    PubMed

    Ward, Michael D

    2016-07-26

    Thin film epitaxy typically invokes a superposition of a pair of rigid two-dimensional lattices with a well-defined orientation governed by some form of commensurism. A report by Meissner et al. in this issue of ACS Nano demonstrates that the organization of organic molecules on substrates may not be that simple, as static distortion waves involving miniscule shifts of atomic positions from substrate lattice points can lead to orientations of a molecular film that cannot be described by often used models. Herein, we provide some highlights of epitaxy, with a focus on configurations that reflect the delicate balance between intermolecular interactions within a molecular film and molecule-substrate interactions. Although geometric models for explaining and predicting epitaxial configurations can be used to guide synthesis of materials, their use must recognize energetic factors and the possibility of more complex, and possibly less predictable, interface structures.

  17. Cancer Cell Fusion: Mechanisms Slowly Unravel

    PubMed Central

    Noubissi, Felicite K.; Ogle, Brenda M.

    2016-01-01

    Although molecular mechanisms and signaling pathways driving invasion and metastasis have been studied for many years, the origin of the population of metastatic cells within the primary tumor is still not well understood. About a century ago, Aichel proposed that cancer cell fusion was a mechanism of cancer metastasis. This hypothesis gained some support over the years, and recently became the focus of many studies that revealed increasing evidence pointing to the possibility that cancer cell fusion probably gives rise to the metastatic phenotype by generating widespread genetic and epigenetic diversity, leading to the emergence of critical populations needed to evolve resistance to the treatment and development of metastasis. In this review, we will discuss the clinical relevance of cancer cell fusion, describe emerging mechanisms of cancer cell fusion, address why inhibiting cancer cell fusion could represent a critical line of attack to limit drug resistance and to prevent metastasis, and suggest one new modality for doing so. PMID:27657058

  18. Unraveling proteins: a molecular mechanics study.

    PubMed Central

    Rohs, R; Etchebest, C; Lavery, R

    1999-01-01

    An internal coordinate molecular mechanics study of unfolding peptide chains by external stretching has been carried out to predict the type of force spectra that may be expected from single-molecule manipulation experiments currently being prepared. Rather than modeling the stretching of a given protein, we have looked at the behavior of simple secondary structure elements (alpha-helix, beta-ribbon, and interacting alpha-helices) to estimate the magnitude of the forces involved in their unfolding or separation and the dependence of these forces on the way pulling is carried out as well as on the length of the structural elements. The results point to a hierarchy of forces covering a surprisingly large range and to important orientational effects in the response to external stress. PMID:10233091

  19. Stability analysis of fixed points via chaos control.

    PubMed

    Locher, M.; Johnson, G. A.; Hunt, E. R.

    1997-12-01

    This paper reviews recent advances in the application of chaos control techniques to the stability analysis of two-dimensional dynamical systems. We demonstrate how the system's response to one or multiple feedback controllers can be utilized to calculate the characteristic multipliers associated with an unstable periodic orbit. The experimental results, obtained for a single and two coupled diode resonators, agree well with the presented theory. (c) 1997 American Institute of Physics. PMID:12779684

  20. Using a Card Trick to Illustrate Fixed Points and Stability

    ERIC Educational Resources Information Center

    Champanerkar, Jyoti; Jani, Mahendra

    2015-01-01

    Mathematical ideas from number theory, group theory, dynamical systems, and computer science have often been used to explain card tricks. Conversely, playing cards have been often used to illustrate the mathematical concepts of probability distributions and group theory. In this paper, we describe how the 21-card trick may be used to illustrate…

  1. Unraveling chromatin structure using magnetic tweezers

    NASA Astrophysics Data System (ADS)

    van Noort, John

    2010-03-01

    The compact, yet dynamic organization of chromatin plays an essential role in regulating gene expression. Although the static structure of chromatin fibers has been studied extensively, the controversy about the higher order folding remains. The compaction of eukaryotic DNA into chromatin has been implicated in the regulation of all DNA processes. To understand the relation between gene regulation and chromatin structure it is essential to uncover the mechanisms by which chromatin fibers fold and unfold. We used magnetic tweezers to probe the mechanical properties of individual nucleosomes and chromatin fibers consisting of a single, well-defined array of 25 nucleosomes. From these studies five major features appeared upon forced extension of chromatin fibers: the elastic stretching of chromatin's higher order structure, the breaking of internucleosomal contacts, unwrapping of the first turn of DNA, unwrapping of the second turn of DNA, and the dissociation of histone octamers. These events occur sequentially at the increasing force. Neighboring nucleosomes stabilize DNA folding into a nucleosome relative to isolated nucleosomes. When an array of nucleosomes is folded into a 30 nm fiber, representing the first level of chromatin condensation, the fiber stretched like a Hookian spring at forces up to 4 pN. Together with a nucleosome-nucleosome stacking energy of 14 kT this points to a solenoid as the underlying topology of the 30 nm fiber. Surprisingly, linker histones do not affect the length or stiffness of the fibers, but stabilize fiber folding up to forces of 7 pN. The stiffness of the folded chromatin fiber points at histone tails that mediate nucleosome stacking. Fibers with a nucleosome repeat length of 167 bp instead of 197 bp are significantly stiffer, consistent with a two-start helical arrangement. The extensive thermal breathing of the chromatin fiber that is a consequence of the observed high compliance provides a structural basis for understanding the

  2. Apparatus for fixing latency

    DOEpatents

    Hall, David R.; Bartholomew, David B.; Moon, Justin; Koehler, Roger O.

    2009-09-08

    An apparatus for fixing computational latency within a deterministic region on a network comprises a network interface modem, a high priority module and at least one deterministic peripheral device. The network interface modem is in communication with the network. The high priority module is in communication with the network interface modem. The at least one deterministic peripheral device is connected to the high priority module. The high priority module comprises a packet assembler/disassembler, and hardware for performing at least one operation. Also disclosed is an apparatus for executing at least one instruction on a downhole device within a deterministic region, the apparatus comprising a control device, a downhole network, and a downhole device. The control device is near the surface of a downhole tool string. The downhole network is integrated into the tool string. The downhole device is in communication with the downhole network.

  3. [Fixed-dose combination].

    PubMed

    Nagai, Yoshio

    2015-03-01

    Many patients with type 2 diabetes mellitus(T2DM) do not achieve satisfactory glycemic control by monotherapy alone, and often require multiple oral hypoglycemic agents (OHAs). Combining OHAs with complementary mechanisms of action is fundamental to the management of T2DM. Fixed-dose combination therapy(FDC) offers a method of simplifying complex regimens. Efficacy and tolerability appear to be similar between FDC and treatment with individual agents. In addition, FDC can enhance adherence and improved adherence may result in improved glycemic control. Four FDC agents are available in Japan: pioglitazone-glimepiride, pioglitazone-metformin, pioglitazone-alogliptin, and voglibose-mitiglinide. In this review, the advantages and disadvantages of these four combinations are identified and discussed. PMID:25812374

  4. Fixed Access Network Sharing

    NASA Astrophysics Data System (ADS)

    Cornaglia, Bruno; Young, Gavin; Marchetta, Antonio

    2015-12-01

    Fixed broadband network deployments are moving inexorably to the use of Next Generation Access (NGA) technologies and architectures. These NGA deployments involve building fiber infrastructure increasingly closer to the customer in order to increase the proportion of fiber on the customer's access connection (Fibre-To-The-Home/Building/Door/Cabinet… i.e. FTTx). This increases the speed of services that can be sold and will be increasingly required to meet the demands of new generations of video services as we evolve from HDTV to "Ultra-HD TV" with 4k and 8k lines of video resolution. However, building fiber access networks is a costly endeavor. It requires significant capital in order to cover any significant geographic coverage. Hence many companies are forming partnerships and joint-ventures in order to share the NGA network construction costs. One form of such a partnership involves two companies agreeing to each build to cover a certain geographic area and then "cross-selling" NGA products to each other in order to access customers within their partner's footprint (NGA coverage area). This is tantamount to a bi-lateral wholesale partnership. The concept of Fixed Access Network Sharing (FANS) is to address the possibility of sharing infrastructure with a high degree of flexibility for all network operators involved. By providing greater configuration control over the NGA network infrastructure, the service provider has a greater ability to define the network and hence to define their product capabilities at the active layer. This gives the service provider partners greater product development autonomy plus the ability to differentiate from each other at the active network layer.

  5. Colligative Properties of Solutions: I. Fixed Concentrations

    NASA Astrophysics Data System (ADS)

    Alexander, Kenneth S.; Biskup, Marek; Chayes, Lincoln

    2005-05-01

    Using the formalism of rigorous statistical mechanics, we study the phenomena of phase separation and freezing-point depression upon freezing of solutions. Specifically, we devise an Ising-based model of a solvent--solute system and show that, in the ensemble with a fixed amount of solute, a macroscopic phase separation occurs in an interval of values of the chemical potential of the solvent. The boundaries of the phase separation domain in the phase diagram are characterized and shown to asymptotically agree with the formulas used in heuristic analyses of freezing-point depression. The limit of infinitesimal concentrations is described in a subsequent paper.

  6. Unraveling Executive Functioning in Dual Diagnosis

    PubMed Central

    Duijkers, Judith C. L. M.; Vissers, Constance Th. W. M.; Egger, Jos I. M.

    2016-01-01

    In mental health, the term dual-diagnosis is used for the co-occurrence of Substance Use Disorder (SUD) with another mental disorder. These co-occurring disorders can have a shared cause, and can cause/intensify each other’s expression. Forming a threat to health and society, dual-diagnosis is associated with relapses in addiction-related behavior and a destructive lifestyle. This is due to a persistent failure to control impulses and the maintaining of inadequate self-regulatory behavior in daily life. Thus, several aspects of executive functioning like inhibitory, shifting and updating processes seem impaired in dual-diagnosis. Executive (dys-)function is currently even seen as a shared underlying key component of most mental disorders. However, the number of studies on diverse aspects of executive functioning in dual-diagnosis is limited. In the present review, a systematic overview of various aspects of executive functioning in dual-diagnosis is presented, striving for a prototypical profile of patients with dual-diagnosis. Looking at empirical results, inhibitory and shifting processes appear to be impaired for SUD combined with schizophrenia, bipolar disorder or cluster B personality disorders. Studies involving updating process tasks for dual-diagnosis were limited. More research that zooms in to the full diversity of these executive functions is needed in order to strengthen these findings. Detailed insight in the profile of strengths and weaknesses that underlies one’s behavior and is related to diagnostic classifications, can lead to tailor-made assessment and indications for treatment, pointing out which aspects need attention and/or training in one’s self-regulative abilities. PMID:27445939

  7. Unraveling Executive Functioning in Dual Diagnosis.

    PubMed

    Duijkers, Judith C L M; Vissers, Constance Th W M; Egger, Jos I M

    2016-01-01

    In mental health, the term dual-diagnosis is used for the co-occurrence of Substance Use Disorder (SUD) with another mental disorder. These co-occurring disorders can have a shared cause, and can cause/intensify each other's expression. Forming a threat to health and society, dual-diagnosis is associated with relapses in addiction-related behavior and a destructive lifestyle. This is due to a persistent failure to control impulses and the maintaining of inadequate self-regulatory behavior in daily life. Thus, several aspects of executive functioning like inhibitory, shifting and updating processes seem impaired in dual-diagnosis. Executive (dys-)function is currently even seen as a shared underlying key component of most mental disorders. However, the number of studies on diverse aspects of executive functioning in dual-diagnosis is limited. In the present review, a systematic overview of various aspects of executive functioning in dual-diagnosis is presented, striving for a prototypical profile of patients with dual-diagnosis. Looking at empirical results, inhibitory and shifting processes appear to be impaired for SUD combined with schizophrenia, bipolar disorder or cluster B personality disorders. Studies involving updating process tasks for dual-diagnosis were limited. More research that zooms in to the full diversity of these executive functions is needed in order to strengthen these findings. Detailed insight in the profile of strengths and weaknesses that underlies one's behavior and is related to diagnostic classifications, can lead to tailor-made assessment and indications for treatment, pointing out which aspects need attention and/or training in one's self-regulative abilities.

  8. Unraveling Executive Functioning in Dual Diagnosis.

    PubMed

    Duijkers, Judith C L M; Vissers, Constance Th W M; Egger, Jos I M

    2016-01-01

    In mental health, the term dual-diagnosis is used for the co-occurrence of Substance Use Disorder (SUD) with another mental disorder. These co-occurring disorders can have a shared cause, and can cause/intensify each other's expression. Forming a threat to health and society, dual-diagnosis is associated with relapses in addiction-related behavior and a destructive lifestyle. This is due to a persistent failure to control impulses and the maintaining of inadequate self-regulatory behavior in daily life. Thus, several aspects of executive functioning like inhibitory, shifting and updating processes seem impaired in dual-diagnosis. Executive (dys-)function is currently even seen as a shared underlying key component of most mental disorders. However, the number of studies on diverse aspects of executive functioning in dual-diagnosis is limited. In the present review, a systematic overview of various aspects of executive functioning in dual-diagnosis is presented, striving for a prototypical profile of patients with dual-diagnosis. Looking at empirical results, inhibitory and shifting processes appear to be impaired for SUD combined with schizophrenia, bipolar disorder or cluster B personality disorders. Studies involving updating process tasks for dual-diagnosis were limited. More research that zooms in to the full diversity of these executive functions is needed in order to strengthen these findings. Detailed insight in the profile of strengths and weaknesses that underlies one's behavior and is related to diagnostic classifications, can lead to tailor-made assessment and indications for treatment, pointing out which aspects need attention and/or training in one's self-regulative abilities. PMID:27445939

  9. Temporal control in fixed-interval schedules.

    PubMed

    Zeiler, M D; Powell, D G

    1994-01-01

    The peak procedure was used to study temporal control in pigeons exposed to seven fixed-interval schedules ranging from 7.5 to 480 s. The focus was on behavior in individual intervals. Quantitative properties of temporal control depended on whether the aspect of behavior considered was initial pause duration, the point of maximum acceleration in responding, the point of maximum deceleration, the point at which responding stopped, or several different statistical derivations of a point of maximum responding. Each aspect produced different conclusions about the nature of temporal control, and none conformed to what was known previously about the way ongoing responding was controlled by time under conditions of differential reinforcement. Existing theory does not explain why Weber's law so rarely fit the results or why each type of behavior seemed unique. These data fit with others suggesting that principles of temporal control may depend on the role played by the particular aspect of behavior in particular situations.

  10. Unraveling multiple changes in complex climate time series using Bayesian inference

    NASA Astrophysics Data System (ADS)

    Berner, Nadine; Trauth, Martin H.; Holschneider, Matthias

    2016-04-01

    Change points in time series are perceived as heterogeneities in the statistical or dynamical characteristics of observations. Unraveling such transitions yields essential information for the understanding of the observed system. The precise detection and basic characterization of underlying changes is therefore of particular importance in environmental sciences. We present a kernel-based Bayesian inference approach to investigate direct as well as indirect climate observations for multiple generic transition events. In order to develop a diagnostic approach designed to capture a variety of natural processes, the basic statistical features of central tendency and dispersion are used to locally approximate a complex time series by a generic transition model. A Bayesian inversion approach is developed to robustly infer on the location and the generic patterns of such a transition. To systematically investigate time series for multiple changes occurring at different temporal scales, the Bayesian inversion is extended to a kernel-based inference approach. By introducing basic kernel measures, the kernel inference results are composed into a proxy probability to a posterior distribution of multiple transitions. Thus, based on a generic transition model a probability expression is derived that is capable to indicate multiple changes within a complex time series. We discuss the method's performance by investigating direct and indirect climate observations. The approach is applied to environmental time series (about 100 a), from the weather station in Tuscaloosa, Alabama, and confirms documented instrumentation changes. Moreover, the approach is used to investigate a set of complex terrigenous dust records from the ODP sites 659, 721/722 and 967 interpreted as climate indicators of the African region of the Plio-Pleistocene period (about 5 Ma). The detailed inference unravels multiple transitions underlying the indirect climate observations coinciding with established

  11. Cook-Levin Theorem Algorithmic-Reducibility/Completeness = Wilson Renormalization-(Semi)-Group Fixed-Points; ``Noise''-Induced Phase-Transitions (NITs) to Accelerate Algorithmics (``NIT-Picking'') REPLACING CRUTCHES!!!: Models: Turing-machine, finite-state-models, finite-automata

    NASA Astrophysics Data System (ADS)

    Young, Frederic; Siegel, Edward

    Cook-Levin theorem theorem algorithmic computational-complexity(C-C) algorithmic-equivalence reducibility/completeness equivalence to renormalization-(semi)-group phase-transitions critical-phenomena statistical-physics universality-classes fixed-points, is exploited via Siegel FUZZYICS =CATEGORYICS = ANALOGYICS =PRAGMATYICS/CATEGORY-SEMANTICS ONTOLOGY COGNITION ANALYTICS-Aristotle ``square-of-opposition'' tabular list-format truth-table matrix analytics predicts and implements ''noise''-induced phase-transitions (NITs) to accelerate versus to decelerate Harel [Algorithmics (1987)]-Sipser[Intro.Thy. Computation(`97)] algorithmic C-C: ''NIT-picking''(!!!), to optimize optimization-problems optimally(OOPO). Versus iso-''noise'' power-spectrum quantitative-only amplitude/magnitude-only variation stochastic-resonance, ''NIT-picking'' is ''noise'' power-spectrum QUALitative-type variation via quantitative critical-exponents variation. Computer-''science''/SEANCE algorithmic C-C models: Turing-machine, finite-state-models, finite-automata,..., discrete-maths graph-theory equivalence to physics Feynman-diagrams are identified as early-days once-workable valid but limiting IMPEDING CRUTCHES(!!!), ONLY IMPEDE latter-days new-insights!!!

  12. Inhibitory avoidance learning in zebrafish (Danio rerio): effects of shock intensity and unraveling differences in task performance.

    PubMed

    Manuel, Remy; Gorissen, Marnix; Roca, Carme Piza; Zethof, Jan; van de Vis, Hans; Flik, Gert; van den Bos, Ruud

    2014-08-01

    The zebrafish (Danio rerio) is increasingly used as a model in neurobehavioral and neuroendocrine studies. The inhibitory avoidance paradigm has been proposed as tool to study mechanisms underlying learning and memory in zebrafish. In this paradigm subjects receive a shock after entering the black compartment of a black-white box. On the next day, latency to enter the black compartment is assessed; higher latencies are indicative of increased avoidance learning. Here, we aimed to understand the effects of different shock intensities (0, 1, 3, and 9 V) and to unravel variation in inhibitory avoidance learning in an in-house reared Tuebingen Long-Fin zebrafish (D. rerio) strain. While median latencies had increased in the 1, 3, and 9 V groups, no increase in median latency was found in the 0 V group. In addition, higher shock intensities resulted in a higher number of avoiders (latency ≥180 s) over nonavoiders (latency <60 s). Both changes are indicative of increased avoidance learning. We assessed whole-body cortisol content and the expression levels of genes relevant to stress, anxiety, fear, and learning 2 h after testing. Shock intensity was associated with whole-body cortisol content and the expression of glucocorticoid receptor alpha [nr3c1(alpha)], cocaine- and amphetamine-regulated transcript (cart4), and mineralocorticoid receptor (nr3c2), while avoidance behavior was associated with whole-body cortisol content only. The inhibitory avoidance paradigm in combination with measuring whole-body cortisol content and gene expression is suitable to unravel (genetic) mechanisms of fear avoidance learning. Our data further show differences in brain-behavior relationships underlying fear avoidance learning and memory in zebrafish. These findings serve as starting point for further unraveling differences in brain-behavior relationships underlying (fear avoidance) learning and memory in zebrafish.

  13. Inhibitory Avoidance Learning in Zebrafish (Danio Rerio): Effects of Shock Intensity and Unraveling Differences in Task Performance

    PubMed Central

    Gorissen, Marnix; Piza Roca, Carme; Zethof, Jan; van de Vis, Hans; Flik, Gert; van den Bos, Ruud

    2014-01-01

    Abstract The zebrafish (Danio rerio) is increasingly used as a model in neurobehavioral and neuroendocrine studies. The inhibitory avoidance paradigm has been proposed as tool to study mechanisms underlying learning and memory in zebrafish. In this paradigm subjects receive a shock after entering the black compartment of a black-white box. On the next day, latency to enter the black compartment is assessed; higher latencies are indicative of increased avoidance learning. Here, we aimed to understand the effects of different shock intensities (0, 1, 3, and 9 V) and to unravel variation in inhibitory avoidance learning in an in-house reared Tuebingen Long-Fin zebrafish (D. rerio) strain. While median latencies had increased in the 1, 3, and 9 V groups, no increase in median latency was found in the 0 V group. In addition, higher shock intensities resulted in a higher number of avoiders (latency ≥180 s) over nonavoiders (latency <60 s). Both changes are indicative of increased avoidance learning. We assessed whole-body cortisol content and the expression levels of genes relevant to stress, anxiety, fear, and learning 2 h after testing. Shock intensity was associated with whole-body cortisol content and the expression of glucocorticoid receptor alpha [nr3c1(alpha)], cocaine- and amphetamine-regulated transcript (cart4), and mineralocorticoid receptor (nr3c2), while avoidance behavior was associated with whole-body cortisol content only. The inhibitory avoidance paradigm in combination with measuring whole-body cortisol content and gene expression is suitable to unravel (genetic) mechanisms of fear avoidance learning. Our data further show differences in brain-behavior relationships underlying fear avoidance learning and memory in zebrafish. These findings serve as starting point for further unraveling differences in brain-behavior relationships underlying (fear avoidance) learning and memory in zebrafish. PMID:25004302

  14. Why to treat subjects as fixed effects.

    PubMed

    Adelman, James S; Estes, Zachary

    2015-09-01

    Adelman, Marquis, Sabatos-DeVito, and Estes (2013) collected word naming latencies from 4 participants who read 2,820 words 50 times each. Their recommendation and practice was that R² targets set for models should take into account subject idiosyncrasies as replicable patterns, equivalent to a subjects-as-fixed-effects assumption. In light of an interaction involving subjects, they broke down the interaction into individual subject data. Courrieu and Rey's (2015) commentary argues that (a) single-subject data need not be more reliable than subject-average data, and (b) anyway, treating groups of subjects as random samples leads to valid conclusions about general mechanisms of reading. Point (a) was not part of Adelman et al.'s claim. In this reply, we examine the consequences of using the fixed-effect assumption. It (a) produces the correct target to check if by-items regression models contain all necessary variables, (b) more accurately constrains cognitive models, (c) more accurately reveals general mechanisms, and (d) can offer more powerful tests of effects. Even when individual differences are not the primary focus of a study, the fixed-effect analysis is often preferable to the random-effects analysis. PMID:26348203

  15. Microbiome to Brain: Unravelling the Multidirectional Axes of Communication.

    PubMed

    El Aidy, Sahar; Stilling, Roman; Dinan, Timothy G; Cryan, John F

    2016-01-01

    The gut microbiome plays a crucial role in host physiology. Disruption of its community structure and function can have wide-ranging effects making it critical to understand exactly how the interactive dialogue between the host and its microbiota is regulated to maintain homeostasis. An array of multidirectional signalling molecules is clearly involved in the host-microbiome communication. This interactive signalling not only impacts the gastrointestinal tract, where the majority of microbiota resides, but also extends to affect other host systems including the brain and liver as well as the microbiome itself. Understanding the mechanistic principles of this inter-kingdom signalling is fundamental to unravelling how our supraorganism function to maintain wellbeing, subsequently opening up new avenues for microbiome manipulation to favour desirable mental health outcome.

  16. Procrastination by pigeons with fixed-interval response requirements.

    PubMed

    Mazur, J E

    1998-03-01

    Two experiments studied the phenomenon of procrastination, in which pigeons chose a larger, more delayed response requirement over a smaller, more immediate response requirement. The response requirements were fixed-interval schedules that did not lead to an immediate food reinforcer, but that interrupted a 55-s period in which food was delivered at random times. The experiments used an adjusting-delay procedure in which the delay to the start of one fixed-interval requirement was varied over trials to estimate an indifference point--a delay at which the two alternatives were chosen about equally often. Experiment 1 found that as the delay to a shorter fixed-interval requirement was increased, the adjusting delay to a longer fixed-interval requirement also increased, and the rate of increase depended on the duration of the longer fixed-interval requirement. Experiment 2 found a strong preference for a fixed delay of 10 s to the start of a fixed-interval requirement compared to a mixed delay of either 0 or 20 s. The results help to distinguish among different equations that might describe the decreasing effectiveness of a response requirement with increasing delay, and they suggest that delayed reinforcers and delayed response requirements have symmetrical but opposite effects on choice.

  17. A Comparison Simulation of Fixed-fixed Type MEMS Switches

    NASA Astrophysics Data System (ADS)

    Rezazadeh, G.; Sadeghian, H.; Malekpour, E.

    2006-04-01

    In the present work pull-in voltage of fixed-fixed end type MEMS switches with variative electrostatic area has been calculated using a distributed model and applying a full nonlinear finite difference discretizing method. The governing nonlinear differential equation has been derived using of the variational principle for multi domain electromechanical coupled system. The numerical results of the beam with variative electrostatic area with the results of Coupled-Domain Finite Element method have been compared and very good agreement has been achieved.

  18. Tipping Points

    NASA Astrophysics Data System (ADS)

    Hansen, J.

    2007-12-01

    A climate tipping point, at least as I have used the phrase, refers to a situation in which a changing climate forcing has reached a point such that little additional forcing (or global temperature change) is needed to cause large, relatively rapid, climate change. Present examples include potential loss of all Arctic sea ice and instability of the West Antarctic and Greenland ice sheets. Tipping points are characterized by ready feedbacks that amplify the effect of forcings. The notion that these may be runaway feedbacks is a misconception. However, present "unrealized" global warming, due to the climate system's thermal inertia, exacerbates the difficulty of avoiding global warming tipping points. I argue that prompt efforts to slow CO2 emissions and absolutely reduce non-CO2 forcings are both essential if we are to avoid tipping points that would be disastrous for humanity and creation, the planet as civilization knows it.

  19. Evidence of the big fix

    NASA Astrophysics Data System (ADS)

    Hamada, Yuta; Kawai, Hikaru; Kawana, Kiyoharu

    2014-06-01

    We give an evidence of the Big Fix. The theory of wormholes and multiverse suggests that the parameters of the Standard Model are fixed in such a way that the total entropy at the late stage of the universe is maximized, which we call the maximum entropy principle. In this paper, we discuss how it can be confirmed by the experimental data, and we show that it is indeed true for the Higgs vacuum expectation value vh. We assume that the baryon number is produced by the sphaleron process, and that the current quark masses, the gauge couplings and the Higgs self-coupling are fixed when we vary vh. It turns out that the existence of the atomic nuclei plays a crucial role to maximize the entropy. This is reminiscent of the anthropic principle, however it is required by the fundamental law in our case.

  20. Fixed Schedules Can Support 21st-Century Skills

    ERIC Educational Resources Information Center

    Formanack, Gail; Pietsch, Laura

    2011-01-01

    The common belief among school librarians is that a flexibly scheduled school library program as opposed to a fixed schedule program is the best choice. After all, there are distinct advantages to the flexible program: students are served at the point of need, skills are not taught in isolation, and collaborative lessons are developed with…

  1. Unravelling the community structure of the climate system by using lags and symbolic time-series analysis

    PubMed Central

    Tirabassi, Giulio; Masoller, Cristina

    2016-01-01

    Many natural systems can be represented by complex networks of dynamical units with modular structure in the form of communities of densely interconnected nodes. Unraveling this community structure from observed data requires the development of appropriate tools, particularly when the nodes are embedded in a regular space grid and the datasets are short and noisy. Here we propose two methods to identify communities, and validate them with the analysis of climate datasets recorded at a regular grid of geographical locations covering the Earth surface. By identifying mutual lags among time-series recorded at different grid points, and by applying symbolic time-series analysis, we are able to extract meaningful regional communities, which can be interpreted in terms of large-scale climate phenomena. The methods proposed here are valuable tools for the study of other systems represented by networks of dynamical units, allowing the identification of communities, through time-series analysis of the observed output signals. PMID:27406342

  2. Unravelling the community structure of the climate system by using lags and symbolic time-series analysis

    NASA Astrophysics Data System (ADS)

    Tirabassi, Giulio; Masoller, Cristina

    2016-07-01

    Many natural systems can be represented by complex networks of dynamical units with modular structure in the form of communities of densely interconnected nodes. Unraveling this community structure from observed data requires the development of appropriate tools, particularly when the nodes are embedded in a regular space grid and the datasets are short and noisy. Here we propose two methods to identify communities, and validate them with the analysis of climate datasets recorded at a regular grid of geographical locations covering the Earth surface. By identifying mutual lags among time-series recorded at different grid points, and by applying symbolic time-series analysis, we are able to extract meaningful regional communities, which can be interpreted in terms of large-scale climate phenomena. The methods proposed here are valuable tools for the study of other systems represented by networks of dynamical units, allowing the identification of communities, through time-series analysis of the observed output signals.

  3. Gold mining on Mayan-Mam territory: social unravelling, discord and distress in the Western highlands of Guatemala.

    PubMed

    Caxaj, C Susana; Berman, Helene; Varcoe, Colleen; Ray, Susan L; Restoulec, Jean-Paul

    2014-06-01

    This article examines the influence of a large-scale mining operation on the health of the community of San Miguel Ixtahuacán, Guatemala. An anti-colonial narrative approach informed by participatory action research principles was employed. Data collection included focus groups and one-on-one interviews from August to November of 2011. Over this period, we interviewed 15 Mam Mayan men and 41 women (n = 56) between the ages of 18 and 64 including health care workers, educators, spiritual leaders, agricultural workers and previous mine employees from 13 villages within the municipality. Participants' accounts pointed to community health experiences of social unravelling characterized by overlapping narratives of a climate of fear and discord and embodied expressions of distress. These findings reveal the interconnected mechanisms by which local mining operations influenced the health of the community, specifically, by introducing new threats to the safety and mental wellbeing of local residents.

  4. Tipping Point

    MedlinePlus

    ... Tipping Point by CPSC Blogger September 22 appliance child Childproofing CPSC danger death electrical fall furniture head injury product safety television tipover tv Watch the video in Adobe Flash format. Almost weekly, we see ...

  5. Spontaneous unraveling of hagfish slime thread skeins is mediated by a seawater-soluble protein adhesive.

    PubMed

    Bernards, Mark A; Oke, Isdin; Heyland, Andreas; Fudge, Douglas S

    2014-04-15

    Hagfishes are known for their ability to rapidly produce vast quantities of slime when provoked. The slime is formed via the interaction between seawater and two components released by the slime glands: mucin vesicles from gland mucous cells, which swell and rupture in seawater to form a network of mucus strands, and intermediate filament-rich threads, which are produced within gland thread cells as tightly coiled bundles called skeins. A previous study showed that the unraveling of skeins from Atlantic hagfish (Myxine glutinosa) requires both the presence of mucins and hydrodynamic mixing. In contrast, skeins from Pacific hagfish (Eptatretus stoutii) unravel in the absence of both mucins and mixing. We tested the hypothesis that spontaneous unraveling of E. stoutii skeins is triggered by the dissolution of a seawater-soluble protein adhesive and the release of stored strain energy within the coiled thread. Here we show that, as predicted by this hypothesis, unraveling can be initiated by a protease under conditions in which unraveling does not normally occur. We also demonstrate, using high resolution scanning electron microscopy, that the treatment of skeins with solutions that cause unraveling also leads to the disappearance of surface and inter-thread features that remain when skeins are washed with stabilizing solutions. Our study provides a mechanism for the deployment of thread skeins in Pacific hagfish slime, and raises the possibility of producing novel biomimetic protein adhesives that are salt, temperature and kosmotrope sensitive.

  6. Fixed Costs and Hours Constraints

    ERIC Educational Resources Information Center

    Johnson, William R.

    2011-01-01

    Hours constraints are typically identified by worker responses to questions asking whether they would prefer a job with more hours and more pay or fewer hours and less pay. Because jobs with different hours but the same rate of pay may be infeasible when there are fixed costs of employment or mandatory overtime premia, the constraint in those…

  7. 29 CFR 1917.120 - Fixed stairways.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 7 2014-07-01 2014-07-01 false Fixed stairways. 1917.120 Section 1917.120 Labor... (CONTINUED) MARINE TERMINALS Terminal Facilities § 1917.120 Fixed stairways. (a) Definition. “Fixed stairway... intergral part of machinery. (b) New installations. (1) Fixed stairs installed after October 3, 1983...

  8. 46 CFR 170.235 - Fixed ballast.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Fixed ballast. 170.235 Section 170.235 Shipping COAST... ALL INSPECTED VESSELS Special Installations § 170.235 Fixed ballast. (a) Fixed ballast, if used, must... shifting of position. (b) Fixed ballast may not be removed from a vessel or relocated unless approved...

  9. 46 CFR 170.235 - Fixed ballast.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Fixed ballast. 170.235 Section 170.235 Shipping COAST... ALL INSPECTED VESSELS Special Installations § 170.235 Fixed ballast. (a) Fixed ballast, if used, must... shifting of position. (b) Fixed ballast may not be removed from a vessel or relocated unless approved...

  10. 29 CFR 1917.120 - Fixed stairways.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 7 2012-07-01 2012-07-01 false Fixed stairways. 1917.120 Section 1917.120 Labor... (CONTINUED) MARINE TERMINALS Terminal Facilities § 1917.120 Fixed stairways. (a) Definition. “Fixed stairway... intergral part of machinery. (b) New installations. (1) Fixed stairs installed after October 3, 1983...

  11. 46 CFR 170.235 - Fixed ballast.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Fixed ballast. 170.235 Section 170.235 Shipping COAST... ALL INSPECTED VESSELS Special Installations § 170.235 Fixed ballast. (a) Fixed ballast, if used, must... shifting of position. (b) Fixed ballast may not be removed from a vessel or relocated unless approved...

  12. 29 CFR 1917.120 - Fixed stairways.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 7 2011-07-01 2011-07-01 false Fixed stairways. 1917.120 Section 1917.120 Labor... (CONTINUED) MARINE TERMINALS Terminal Facilities § 1917.120 Fixed stairways. (a) Definition. “Fixed stairway... intergral part of machinery. (b) New installations. (1) Fixed stairs installed after October 3, 1983...

  13. 46 CFR 170.235 - Fixed ballast.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Fixed ballast. 170.235 Section 170.235 Shipping COAST... ALL INSPECTED VESSELS Special Installations § 170.235 Fixed ballast. (a) Fixed ballast, if used, must... shifting of position. (b) Fixed ballast may not be removed from a vessel or relocated unless approved...

  14. 29 CFR 1917.120 - Fixed stairways.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 7 2010-07-01 2010-07-01 false Fixed stairways. 1917.120 Section 1917.120 Labor... (CONTINUED) MARINE TERMINALS Terminal Facilities § 1917.120 Fixed stairways. (a) Definition. “Fixed stairway... intergral part of machinery. (b) New installations. (1) Fixed stairs installed after October 3, 1983...

  15. 46 CFR 170.235 - Fixed ballast.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Fixed ballast. 170.235 Section 170.235 Shipping COAST... ALL INSPECTED VESSELS Special Installations § 170.235 Fixed ballast. (a) Fixed ballast, if used, must... shifting of position. (b) Fixed ballast may not be removed from a vessel or relocated unless approved...

  16. Unraveling shock-induced chemistry using ultrafast lasers

    SciTech Connect

    Moore, David S

    2009-01-01

    The exquisite time synchronicity between shock and diagnostics needed to unravel chemical events occurring in picoseconds has been achieved using a shaped ultrafast laser pulse to both drive the shocks and interrogate the sample via a multiplicity of optical diagnostics. The shaped laser drive pulse can produce well-controlled shock states of sub-ns duration with sub-10 ps risetimes, sufficient for investigation of fast reactions or phase transformations in a thin layer with picosecond time resolution. The shock state is characterized using ultrafast dynamic ellipsometry (UDE) in either planar or Gaussian spatial geometries, the latter allowing measurements of the equation of state of materials at a range of stresses in a single laser pulse. Time-resolved processes in materials are being interrogated using UDE, ultrafast infrared absorption, ultrafast UV/visible absorption, and femtosecond stimulated Raman spectroscopy. Using these tools we showed that chemistry in an energetic thin film starts only after an induction time of a few tens of ps, an observation that allows differentiation between proposed shock-induced reaction mechanisms. These tools are presently being applied to a variety of energetic and reactive sample systems, from nitromethane and carbon disulfide, to micro-engineered interfaces in tunable energetic mixtures.

  17. Unraveling shock-induced chemistry using ultrafast lasers

    SciTech Connect

    Moore, David Steven

    2010-12-06

    The exquisite time synchronicity between shock and diagnostics needed to unravel chemical events occurring in picoseconds has been achieved using a shaped ultrafast laser pulse to both drive the shocks and interrogate the sample via a multiplicity of optical diagnostics. The shaped laser drive pulse can produce well-controlled shock states of sub-ns duration with sub-10 ps risetimes, sufficient for investigation offast reactions or phase transformations in a thin layer with picosecond time resolution. The shock state is characterized using ultrafast dynamic ellipsometry (UDE) in either planar or Gaussian spatial geometries, the latter allowing measurements of the equation of state of materials at a range of stresses in a single laser pulse. Time-resolved processes in materials are being interrogated using UDE, ultrafast infrared absorption, ultrafast UV/visible absorption, and femtosecond stimulated Raman spectroscopy. Using these tools we showed that chemistry in an energetic thin film starts only after an induction time of a few tens of ps, an observation that allows differentiation between proposed shock-induced reaction mechanisms. These tools are presently being applied to a variety of energetic and reactive sample systems, from nitromethane and carbon disulfide, to microengineered interfaces in tunable energetic mixtures. Recent results will be presented, and future trends outlined.

  18. Unraveling the Determinants of Cancer Patients' Intention to Express Concerns.

    PubMed

    Brandes, Kim; Linn, Annemiek J; Smit, Edith G; van Weert, Julia C M

    2016-01-01

    Little is known about the behavioral determinants that underlie cancer patients' intention to express concerns during a consultation. This information can be relevant to developing effective interventions for cancer patients. In this study, the integrative model of behavioral prediction (IMBP) is used as a framework to unravel the determinants of patients' intention to express concerns. The objectives of this study are to examine which of the IMBP determinants (attitude, perceived social norm, and/or self-efficacy) are significantly related to intention and what content of these determinants can be targeted to effect a change in patients' intention. An online survey based on the IMBP determinants was distributed. A total of 236 cancer patients and cancer survivors participated. The results of the survey showed that patients' attitudes and perceived social norm were the most important determinants of their intention to express concerns. The largest change in patients' intention might be achieved by targeting the affective attitude, referring to the extent to which patients believe that expressing concerns is (un)pleasant, and the social norm, referring to the extent to which patients feel (un)supported by significant others in expressing concerns. PMID:26735084

  19. The triple point of sulfur hexafluoride

    NASA Astrophysics Data System (ADS)

    Rourke, P. M. C.

    2016-04-01

    A cryogenic fixed point cell has been filled with high purity (99.999%) sulfur hexafluoride (SF6) and measured in an adiabatic closed-cycle cryostat system. Temperature measurements of the SF6 melting curve were performed using a capsule-type standard platinum resistance thermometer (CSPRT) calibrated over the International Temperature Scale of 1990 (ITS-90) subrange from the triple point of equilibrium hydrogen to the triple point of water. The measured temperatures were corrected by 0.37 mK for the effects of thermometer self-heating, and the liquidus-point temperature estimated by extrapolation to melted fraction F  =  1 of a simple linear regression versus melted fraction F in the range F  =  0.53 to 0.84. Based on this measurement, the temperature of the triple point of sulfur hexafluoride is shown to be 223.555 23(49) K (k  =  1) on the ITS-90. This value is in excellent agreement with the best prior measurements reported in the literature, but with considerably smaller uncertainty. An analysis of the detailed uncertainty budget of this measurement suggests that if the triple point of sulfur hexafluoride were to be included as a defining fixed point of the next revision of the International Temperature Scale, it could do so with a total realization uncertainty of approximately 0.43 mK, slightly larger than the realization uncertainties of the defining fixed points of the ITS-90. Since the combined standard uncertainty of this SF6 triple point temperature determination is dominated by chemical impurity effects, further research exploring gas purification techniques and the influence of specific impurity species on the SF6 triple point temperature may bring the realization uncertainty of SF6 as a fixed point material into the range of the defining fixed points of the ITS-90.

  20. Variable delivery, fixed displacement pump

    DOEpatents

    Sommars, Mark F.

    2001-01-01

    A variable delivery, fixed displacement pump comprises a plurality of pistons reciprocated within corresponding cylinders in a cylinder block. The pistons are reciprocated by rotation of a fixed angle swash plate connected to the pistons. The pistons and cylinders cooperate to define a plurality of fluid compression chambers each have a delivery outlet. A vent port is provided from each fluid compression chamber to vent fluid therefrom during at least a portion of the reciprocal stroke of the piston. Each piston and cylinder combination cooperates to close the associated vent port during another portion of the reciprocal stroke so that fluid is then pumped through the associated delivery outlet. The delivery rate of the pump is varied by adjusting the axial position of the swash plate relative to the cylinder block, which varies the duration of the piston stroke during which the vent port is closed.

  1. Fixed target flammable gas upgrades

    SciTech Connect

    Schmitt, R.; Squires, B.; Gasteyer, T.; Richardson, R.

    1996-12-01

    In the past, fixed target flammable gas systems were not supported in an organized fashion. The Research Division, Mechanical Support Department began to support these gas systems for the 1995 run. This technical memo describes the new approach being used to supply chamber gasses to fixed target experiments at Fermilab. It describes the engineering design features, system safety, system documentation and performance results. Gas mixtures provide the medium for electron detection in proportional and drift chambers. Usually a mixture of a noble gas and a polyatomic quenching gas is used. Sometimes a small amount of electronegative gas is added as well. The mixture required is a function of the specific chamber design, including working voltage, gain requirements, high rate capability, aging and others. For the 1995 fixed target run all the experiments requested once through gas systems. We obtained a summary of problems from the 1990 fixed target run and made a summary of the operations logbook entries from the 1991 run. These summaries primarily include problems involving flammable gas alarms, but also include incidents where Operations was involved or informed. Usually contamination issues were dealt with by the experimenters. The summaries are attached. We discussed past operational issues with the experimenters involved. There were numerous incidents of drift chamber failure where contaminated gas was suspect. However analyses of the gas at the time usually did not show any particular problems. This could have been because the analysis did not look for the troublesome component, the contaminant was concentrated in the gas over the liquid and vented before the sample was taken, or that contaminants were drawn into the chambers directly through leaks or sub-atmospheric pressures. After some study we were unable to determine specific causes of past contamination problems, although in argon-ethane systems the problems were due to the ethane only.

  2. Unravelling genetics at the top: mountain islands or isolated belts?

    PubMed Central

    García-Fernández, Alfredo; Segarra-Moragues, Jose Gabriel; Widmer, Alex; Escudero, Adrian; Iriondo, José María

    2012-01-01

    Background and Aims In mountain plant populations, local adaptation has been described as one of the main responses to climate warming, allowing plants to persist under stressful conditions. This is especially the case for marginal populations at their lowest elevation, as they are highly vulnerable. Adequate levels of genetic diversity are required for selection to take place, while high levels of altitudinal gene flow are seen as a major limiting factor potentially precluding local adaptation processes. Thus, a compromise between genetic diversity and gene flow seems necessary to guarantee persistence under oncoming conditions. It is therefore critical to determine if gene flow occurs preferentially between mountains at similar altitudinal belts, promoting local adaptation at the lowest populations, or conversely along altitude within each mountain. Methods Microsatellite markers were used to unravel genetic diversity and population structure, inbreeding and gene flow of populations at two nearby altitudinal gradients of Silene ciliata, a Mediterranean high-mountain cushion plant. Key Results Genetic diversity and inbreeding coefficients were similar in all populations. Substantial gene flow was found both along altitudinal gradients and horizontally within each elevation belt, although greater values were obtained along altitudinal gradients. Gene flow may be responsible for the homogeneous levels of genetic diversity found among populations. Bayesian cluster analyses also suggested that shifts along altitudinal gradients are the most plausible scenario. Conclusions Past population shifts associated with glaciations and interglacial periods in temperate mountains may partially explain current distributions of genetic diversity and population structure. In spite of the predominance of gene flow along the altitudinal gradients, local genetic differentiation of one of the lower populations together with the detection of one outlier locus might support the existence

  3. 47 CFR 74.644 - Minimum path lengths for fixed links.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false Minimum path lengths for fixed links. 74.644... Auxiliary Stations § 74.644 Minimum path lengths for fixed links. (a) The distance between end points of a... accordance with the equation set forth below. Frequency band(MHz) Minimum path length(km) Below 1,990 n/a...

  4. 47 CFR 74.644 - Minimum path lengths for fixed links.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 4 2013-10-01 2013-10-01 false Minimum path lengths for fixed links. 74.644... Auxiliary Stations § 74.644 Minimum path lengths for fixed links. (a) The distance between end points of a... accordance with the equation set forth below. Frequency band(MHz) Minimum path length(km) Below 1,990 n/a...

  5. 47 CFR 74.644 - Minimum path lengths for fixed links.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 4 2014-10-01 2014-10-01 false Minimum path lengths for fixed links. 74.644... Auxiliary Stations § 74.644 Minimum path lengths for fixed links. (a) The distance between end points of a... accordance with the equation set forth below. Frequency band(MHz) Minimum path length(km) Below 1,990 n/a...

  6. Unraveling the reaction mechanisms governing methanol-to-olefins catalysis by theory and experiment.

    PubMed

    Hemelsoet, Karen; Van der Mynsbrugge, Jeroen; De Wispelaere, Kristof; Waroquier, Michel; Van Speybroeck, Veronique

    2013-06-01

    The conversion of methanol to olefins (MTO) over a heterogeneous nanoporous catalyst material is a highly complex process involving a cascade of elementary reactions. The elucidation of the reaction mechanisms leading to either the desired production of ethene and/or propene or undesired deactivation has challenged researchers for many decades. Clearly, catalyst choice, in particular topology and acidity, as well as the specific process conditions determine the overall MTO activity and selectivity; however, the subtle balances between these factors remain not fully understood. In this review, an overview of proposed reaction mechanisms for the MTO process is given, focusing on the archetypal MTO catalysts, H-ZSM-5 and H-SAPO-34. The presence of organic species, that is, the so-called hydrocarbon pool, in the inorganic framework forms the starting point for the majority of the mechanistic routes. The combination of theory and experiment enables a detailed description of reaction mechanisms and corresponding reaction intermediates. The identification of such intermediates occurs by different spectroscopic techniques, for which theory and experiment also complement each other. Depending on the catalyst topology, reaction mechanisms proposed thus far involve aromatic or aliphatic intermediates. Ab initio simulations taking into account the zeolitic environment can nowadays be used to obtain reliable reaction barriers and chemical kinetics of individual reactions. As a result, computational chemistry and by extension computational spectroscopy have matured to the level at which reliable theoretical data can be obtained, supplying information that is very hard to acquire experimentally. Special emphasis is given to theoretical developments that open new perspectives and possibilities that aid to unravel a process as complex as methanol conversion over an acidic porous material.

  7. Unraveling the reaction mechanisms governing methanol-to-olefins catalysis by theory and experiment.

    PubMed

    Hemelsoet, Karen; Van der Mynsbrugge, Jeroen; De Wispelaere, Kristof; Waroquier, Michel; Van Speybroeck, Veronique

    2013-06-01

    The conversion of methanol to olefins (MTO) over a heterogeneous nanoporous catalyst material is a highly complex process involving a cascade of elementary reactions. The elucidation of the reaction mechanisms leading to either the desired production of ethene and/or propene or undesired deactivation has challenged researchers for many decades. Clearly, catalyst choice, in particular topology and acidity, as well as the specific process conditions determine the overall MTO activity and selectivity; however, the subtle balances between these factors remain not fully understood. In this review, an overview of proposed reaction mechanisms for the MTO process is given, focusing on the archetypal MTO catalysts, H-ZSM-5 and H-SAPO-34. The presence of organic species, that is, the so-called hydrocarbon pool, in the inorganic framework forms the starting point for the majority of the mechanistic routes. The combination of theory and experiment enables a detailed description of reaction mechanisms and corresponding reaction intermediates. The identification of such intermediates occurs by different spectroscopic techniques, for which theory and experiment also complement each other. Depending on the catalyst topology, reaction mechanisms proposed thus far involve aromatic or aliphatic intermediates. Ab initio simulations taking into account the zeolitic environment can nowadays be used to obtain reliable reaction barriers and chemical kinetics of individual reactions. As a result, computational chemistry and by extension computational spectroscopy have matured to the level at which reliable theoretical data can be obtained, supplying information that is very hard to acquire experimentally. Special emphasis is given to theoretical developments that open new perspectives and possibilities that aid to unravel a process as complex as methanol conversion over an acidic porous material. PMID:23595911

  8. Widespread bullous fixed drug eruption

    PubMed Central

    Patell, Rushad D; Dosi, Rupal V; Shah, Purav C; Joshi, Harshal S

    2014-01-01

    A 53-year-old man developed a widespread erythematous eruption which rapidly evolved into fluid-filled bulla mostly involving the distal areas of all four limbs and erosions on the oral as well as anogenital mucosa. Based on clinical presentation, chronology of drug exposure, past events and histopathology as diagnosis of widespread bullous fixed drug eruption was made over Steven Johnson-toxic epidermal necrolysis syndrome. Steroids were deferred and the lesions healed with minimal pigmentation within a week. Differentiating between the two entities has been historically difficult, and yet can have significant therapeutic and prognostic implications. PMID:24510691

  9. Widespread bullous fixed drug eruption.

    PubMed

    Patell, Rushad D; Dosi, Rupal V; Shah, Purav C; Joshi, Harshal S

    2014-02-07

    A 53-year-old man developed a widespread erythematous eruption which rapidly evolved into fluid-filled bulla mostly involving the distal areas of all four limbs and erosions on the oral as well as anogenital mucosa. Based on clinical presentation, chronology of drug exposure, past events and histopathology as diagnosis of widespread bullous fixed drug eruption was made over Steven Johnson-toxic epidermal necrolysis syndrome. Steroids were deferred and the lesions healed with minimal pigmentation within a week. Differentiating between the two entities has been historically difficult, and yet can have significant therapeutic and prognostic implications.

  10. Unraveling the chemical space of terrestrial and meteoritic organic matter

    NASA Astrophysics Data System (ADS)

    Schmitt-Kopplin, Philippe; Harir, Mourad; Hertkorn, Norbert; Kanawati, Basem; Ruf, Alexander; Quirico, Eric; Bonal, Lydie; Beck, Pierre; Gabelica, Zelimir

    2015-04-01

    )High resolution analytical approaches will be presented in their application to unravel the chemical nature and organic signatures in bio-geosystems and especially in selected chondritic (organic and ordinary) and achondritic meteorites. We will focus on thermal effects in CM types of materials and describe the effect of shock events on the changes in chemodiversity and the formation of unique novel organic compounds using high magnetic field ultrahigh resolution mass spectrometry (12 Tesla ion cyclotron resonance Fourier transform mass spectrometry - ICR-FT/MS) and nuclear magnetic resonance spectroscopy (Cryo 800MHz NMR).

  11. FixO3 Network Project: Integration, harmonization and innovation

    NASA Astrophysics Data System (ADS)

    Lampitt, Richard; Cristini, Luisa

    2016-04-01

    The Fixed point Open Ocean Observatory network (FixO3, http://www.fixo3.eu/) seeks to integrate 23 European open ocean fixed point observatories in the Atlantic Ocean and Mediterranean Sea and to improve access to these infrastructures for the broader community. These provide multidisciplinary observations from the air-sea interface to the deep seafloor. Started in September 2013 with a budget of 7 Million Euros over 4 years, the project has 29 partners drawn from academia, research institutions and SME's coordinated by the National Oceanography Centre, UK. The project is structured in 12 Work Packages aimed to: • integrate and harmonise the current infrastructures and processes • offer free access to observatory infrastructures to those who do not have such access, and free and open data services and products • innovate and enhance the current capability for multidisciplinary in situ ocean observation Here we present the programme's key achievements mid-way, the current activities and expected results. Emphasis will be on FixO3-generated tools and products and their applications for the wider oceanographic community for the benefit of science, industry and policy.

  12. Global Positioning System Antenna Fixed Height Tripod Adapter

    NASA Technical Reports Server (NTRS)

    Dinardo, Steven J.; Smith, Mark A.

    1997-01-01

    An improved Global Positioning em antenna adaptor allows fixed antenna height measurements by removably attaching an adaptor plate to a conventional surveyor's tripod. Antenna height is controlled by an antenna boom which is a fixed length rod. The antenna is attached to one end of the boom. The opposite end of the boom tapers to a point sized to fit into a depression at the center of survey markers. The boom passes through the hollow center of a universal ball joint which is mounted at the center of the adaptor plate so that the point of the rod can be fixed in the marker's central depression. The mountains of the ball joint allow the joint to be moved horizontally in any direction relative to the tripod. When the ball joint is moved horizontally, the angle between the boom and the vertical changes because the boom's position is fixed at its lower end. A spirit level attached to the rod allows an operator to determine when the boom is plumb. The position of the ball joint is adjusted horizontally until the boom is plumb. At that time the antenna is positioned exactly over the center of the monument and the elevation of the antenna is precisely set by the length of the boom.

  13. 29 CFR 1917.118 - Fixed ladders.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 7 2011-07-01 2011-07-01 false Fixed ladders. 1917.118 Section 1917.118 Labor Regulations...) MARINE TERMINALS Terminal Facilities § 1917.118 Fixed ladders. (a) Scope and applicability. This section applies to all fixed ladders except: (1) Ladders forming an integral part of railway cars,...

  14. 29 CFR 1910.27 - Fixed ladders.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 5 2013-07-01 2013-07-01 false Fixed ladders. 1910.27 Section 1910.27 Labor Regulations... OCCUPATIONAL SAFETY AND HEALTH STANDARDS Walking-Working Surfaces § 1910.27 Fixed ladders. (a) Design... those specified in § 1910.25. All wood parts of fixed ladders shall meet the requirements of §...

  15. 29 CFR 1910.27 - Fixed ladders.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 5 2012-07-01 2012-07-01 false Fixed ladders. 1910.27 Section 1910.27 Labor Regulations... OCCUPATIONAL SAFETY AND HEALTH STANDARDS Walking-Working Surfaces § 1910.27 Fixed ladders. (a) Design... those specified in § 1910.25. All wood parts of fixed ladders shall meet the requirements of §...

  16. 29 CFR 1910.27 - Fixed ladders.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 5 2014-07-01 2014-07-01 false Fixed ladders. 1910.27 Section 1910.27 Labor Regulations... OCCUPATIONAL SAFETY AND HEALTH STANDARDS Walking-Working Surfaces § 1910.27 Fixed ladders. (a) Design... those specified in § 1910.25. All wood parts of fixed ladders shall meet the requirements of §...

  17. Removal of well-fixed fixed femoral stems.

    PubMed

    Laffosse, J-M

    2016-02-01

    The removal of a well-fixed prosthetic stem raises technical challenges. The objective is not only to remove the material, but also to prepare the implantation of a new prosthesis. Cemented stems are only very rarely unremovable; extraction of the cement mantle and plug raises the greatest difficulties. The main risk is cortex perforation, and a radiograph should be obtained at the slightest doubt. The removal of cementless stems carries a higher risk of fracture. Difficulties should be anticipated based on thorough familiarity with the implant design and on evaluations of implant fixation and bone stock. The intramedullary approach is usually sufficient to extract a cemented or cementless, well fixed, standard stem. Routine use of a transfemoral approach is warranted only in the following situations: revision surgery for infection, S-shaped stem, long stem, curvature or angulation of the femoral shaft, or unfeasible hip dislocation. However, the possibility that the intramedullary approach may need to be converted to a transfemoral approach should be anticipated. Thus, preoperative planning must include determination of the optimal length of a femoral osteotomy or femoral flap, should one be needed, and the surgeon must have access to all the revision implants and tools that might be needed for re-implantation. Experience with the various techniques is indispensable, as a well-performed extensive approach is associated with less morbidity than a fracture or trajectory error. There are three main techniques, which are described here: intramedullary extraction of a cementless stem, intramedullary extraction of a cemented stem, and transfemoral extraction through an extended trochanterotomy. The patients should receive detailed information on the difficulties of femoral stem removal and on the available solutions. PMID:26797009

  18. Holographic Investigation Of Different Types Of Surgical Fixing Devices

    NASA Astrophysics Data System (ADS)

    Podbielska, Halina; Kasprzak, Henryk; von Bally, Gert

    1989-01-01

    The method of double-exposure holographic interferometry was applied to study the behavior of lower leg bones supported with different fixing devices. The torsion and bending was examined for both types of fixators: an external one (Orthofix type 10000) and an internal one (osteosynthesis AO plate, Howmedica). The influence of the fixation on the mechanical response to the external load of the supported tibial shaft is discussed. The advantages of holographic interferometry in the above investigation are pointed out.

  19. Simple Fixed Functional Space Maintainer

    PubMed Central

    Sarawgi, Aditi; Marwah, Nikhil; Gumber, Parvind; Dutta, Samir

    2014-01-01

    ABSTRACT% Premature loss of a primary tooth is one of the most common etiology for malocclusion. Space maintainers are employed to prevent this complication. In anterior region, esthetics is an important concern along with function and space management. Fiber-reinforced composite (FRC) retained space maintainer solves all these purposes ef ficiently and ef fectively. In addition, the technique is simple and the appliance is very comfortable inside the oral cavity. Here is a case of premature loss of anterior primary tooth which was replaced by FRC retained esthetic functional space maintainer. The appliance was found to be functioning satisfactorily inside the oral cavity till the last visit (1 Year). How to cite this article: Goenka P, Sarawgi A, Marwah N, Gumber P, Dutta S. Simple Fixed Functional Space Maintainer. Int J Clin Pediatr Dent 2014;7(3):225-228. PMID:25709309

  20. Simple fixed functional space maintainer.

    PubMed

    Goenka, Puneet; Sarawgi, Aditi; Marwah, Nikhil; Gumber, Parvind; Dutta, Samir

    2014-01-01

    Premature loss of a primary tooth is one of the most common etiology for malocclusion. Space maintainers are employed to prevent this complication. In anterior region, esthetics is an important concern along with function and space management. Fiber-reinforced composite (FRC) retained space maintainer solves all these purposes ef ficiently and ef fectively. In addition, the technique is simple and the appliance is very comfortable inside the oral cavity. Here is a case of premature loss of anterior primary tooth which was replaced by FRC retained esthetic functional space maintainer. The appliance was found to be functioning satisfactorily inside the oral cavity till the last visit (1 Year). How to cite this article: Goenka P, Sarawgi A, Marwah N, Gumber P, Dutta S. Simple Fixed Functional Space Maintainer. Int J Clin Pediatr Dent 2014;7(3):225-228.

  1. Controlling superconductivity by tunable quantum critical points.

    PubMed

    Seo, S; Park, E; Bauer, E D; Ronning, F; Kim, J N; Shim, J-H; Thompson, J D; Park, Tuson

    2015-03-04

    The heavy fermion compound CeRhIn5 is a rare example where a quantum critical point, hidden by a dome of superconductivity, has been explicitly revealed and found to have a local nature. The lack of additional examples of local types of quantum critical points associated with superconductivity, however, has made it difficult to unravel the role of quantum fluctuations in forming Cooper pairs. Here, we show the precise control of superconductivity by tunable quantum critical points in CeRhIn5. Slight tin-substitution for indium in CeRhIn5 shifts its antiferromagnetic quantum critical point from 2.3 GPa to 1.3 GPa and induces a residual impurity scattering 300 times larger than that of pure CeRhIn5, which should be sufficient to preclude superconductivity. Nevertheless, superconductivity occurs at the quantum critical point of the tin-doped metal. These results underline that fluctuations from the antiferromagnetic quantum criticality promote unconventional superconductivity in CeRhIn5.

  2. Controlling superconductivity by tunable quantum critical points.

    PubMed

    Seo, S; Park, E; Bauer, E D; Ronning, F; Kim, J N; Shim, J-H; Thompson, J D; Park, Tuson

    2015-01-01

    The heavy fermion compound CeRhIn5 is a rare example where a quantum critical point, hidden by a dome of superconductivity, has been explicitly revealed and found to have a local nature. The lack of additional examples of local types of quantum critical points associated with superconductivity, however, has made it difficult to unravel the role of quantum fluctuations in forming Cooper pairs. Here, we show the precise control of superconductivity by tunable quantum critical points in CeRhIn5. Slight tin-substitution for indium in CeRhIn5 shifts its antiferromagnetic quantum critical point from 2.3 GPa to 1.3 GPa and induces a residual impurity scattering 300 times larger than that of pure CeRhIn5, which should be sufficient to preclude superconductivity. Nevertheless, superconductivity occurs at the quantum critical point of the tin-doped metal. These results underline that fluctuations from the antiferromagnetic quantum criticality promote unconventional superconductivity in CeRhIn5. PMID:25737108

  3. Unraveling topography around subduction zones from laboratory models

    NASA Astrophysics Data System (ADS)

    Husson, Laurent; Guillaume, Benjamin; Funiciello, Francesca; Faccenna, Claudio; Royden, Leigh H.

    2012-03-01

    The relief around subduction zones results from the interplay of dynamic processes that may locally exceed the (iso)static contributions. The viscous dissipation of the energy in and around subduction zones is capable of generating kilometer scale vertical ground movements. In order to evaluate dynamic topography in a self-consistent subduction system, we carried out a set of laboratory experiments, wherein the lithosphere and mantle are simulated by means of Newtonian viscous materials, namely silicone putty and glucose syrup. Models are kept in their most simple form and are made of negative buoyancy plates, of variable width and thickness, freely plunging into the syrup. The surface of the model and the top of the slab are scanned in three dimensions. A forebulge systematically emerges from the bending of the viscous plate, adjacent to the trench. With a large wavelength, dynamic pressure offsets the foreside and backside of the slab by ~ 500 m on average. The suction, that accompanies the vertical descent of the slab depresses the surface on both sides. At a distance equal to the half-width of the slab, the topographic depression amounts to ~ 500 m on average and becomes negligible at a distance that equals the width of the slab. In order to explore the impact of slab rollback on the topography, the trailing edge of the plates is alternatively fixed to (fixed mode) and freed from (free mode) the end wall of the tank. Both the pressure and suction components of the topography are ~ 30% lower in the free mode, indicating that slab rollback fosters the dynamic subsidence of upper plates. Our models are compatible with first order observations of the topography around the East Scotia, Tonga, Kermadec and Banda subduction zones, which exhibit anomalous depths of nearly 1 km as compared to adjacent sea floor of comparable age.

  4. Expanding the regulatory network that controls nitrogen fixation in Sinorhizobium meliloti: elucidating the role of the two-component system hFixL-FxkR.

    PubMed

    Reyes-González, Alma; Talbi, Chouhra; Rodríguez, Susana; Rivera, Patricia; Zamorano-Sánchez, David; Girard, Lourdes

    2016-06-01

    In Sinorhizobium meliloti, nitrogen fixation is regulated in response to oxygen concentration through the FixL-FixJ two-component system (TCS). Besides this conserved TCS, the field isolate SM11 also encodes the hFixL-FxkR TCS, which is responsible for the microoxic response in Rhizobium etli. Through genetic and physiological assays, we evaluated the role of the hFixL-FxkR TCS in S. meliloti SM11. Our results revealed that this regulatory system activates the expression of a fixKf orthologue (fixKa), in response to low oxygen concentration. Null mutations in either hFixL or FxkR promote upregulation of fixK1, a direct target of FixJ. Furthermore, the absence of this TCS translates into higher nitrogen fixation values as well as higher expression of fixN1 in nodules. Individual mutations in each of the fixK-like regulators encoded in the S. meliloti SM11 genome do not completely restrict fixN1 or fixN2 expression, pointing towards redundancy among these regulators. Both copies of fixN are necessary to achieve optimal levels of nitrogen fixation. This work provides evidence that the hFixL-FxkR TCS is activated in response to low oxygen concentration in S. meliloti SM11 and that it negatively regulates the expression of fixK1, fixN1 and nitrogen fixation. PMID:27010660

  5. Expanding the regulatory network that controls nitrogen fixation in Sinorhizobium meliloti: elucidating the role of the two-component system hFixL-FxkR.

    PubMed

    Reyes-González, Alma; Talbi, Chouhra; Rodríguez, Susana; Rivera, Patricia; Zamorano-Sánchez, David; Girard, Lourdes

    2016-06-01

    In Sinorhizobium meliloti, nitrogen fixation is regulated in response to oxygen concentration through the FixL-FixJ two-component system (TCS). Besides this conserved TCS, the field isolate SM11 also encodes the hFixL-FxkR TCS, which is responsible for the microoxic response in Rhizobium etli. Through genetic and physiological assays, we evaluated the role of the hFixL-FxkR TCS in S. meliloti SM11. Our results revealed that this regulatory system activates the expression of a fixKf orthologue (fixKa), in response to low oxygen concentration. Null mutations in either hFixL or FxkR promote upregulation of fixK1, a direct target of FixJ. Furthermore, the absence of this TCS translates into higher nitrogen fixation values as well as higher expression of fixN1 in nodules. Individual mutations in each of the fixK-like regulators encoded in the S. meliloti SM11 genome do not completely restrict fixN1 or fixN2 expression, pointing towards redundancy among these regulators. Both copies of fixN are necessary to achieve optimal levels of nitrogen fixation. This work provides evidence that the hFixL-FxkR TCS is activated in response to low oxygen concentration in S. meliloti SM11 and that it negatively regulates the expression of fixK1, fixN1 and nitrogen fixation.

  6. Unraveling the Relationship between Organizational Career Management and the Need for External Career Counseling

    ERIC Educational Resources Information Center

    Verbruggen, Marijke; Sels, Luc; Forrier, Anneleen

    2007-01-01

    This article unravels the relationship between organizational career management and the need for external career counseling. We conducted a path analysis using data of 803 Flemish employees. The results indicate a three-way relationship between organizational career management and external career counseling. First, experiencing organizational…

  7. Unraveling the Complexity of Student Teachers' Learning in and from the Workplace

    ERIC Educational Resources Information Center

    Leeferink, Han; Koopman, Maaike; Beijaard, Douwe; Ketelaar, Evelien

    2015-01-01

    This study reports on how student teachers' workplace experiences were transformed into learning experiences. In total, 26 stories from 10 student teachers were collected by means of digital logs and in-depth interviews and unraveled using a new technique of reconstructing stories into webs. In these webs, the factors that played a role in student…

  8. Unraveling the Effects of Critical Thinking Instructions, Practice, and Self-Explanation on Students' Reasoning Performance

    ERIC Educational Resources Information Center

    Heijltjes, Anita; van Gog, Tamara; Leppink, Jimmie; Paas, Fred

    2015-01-01

    Acquisition of critical thinking skills is considered an important goal in higher education, but it is still unclear which specific instructional techniques are effective for fostering it. The main aim of this study was to unravel the impact of critical thinking instructions, practice, and self-explanation prompts during practice, on students'…

  9. Unravelling the Sources of Adolescent Substance Use: A Test of Rival Theories

    ERIC Educational Resources Information Center

    Jonson, Cheryl Lero; McArthur, Rachel; Cullen, Francis T.; Wilcox, Pamela

    2012-01-01

    Among any cohort of American youths, some will use drugs and alcohol whereas others will not. Further, some youngsters will not only use these illegal substances but also abuse them, at times wreaking havoc with their lives and ruining their futures. The purpose of this study is to attempt to unravel this heterogeneity of substance abuse; that is,…

  10. Fixed drug eruption in Nigeria.

    PubMed

    Nnoruka, Edith N; Ikeh, V O; Mbah, A U

    2006-09-01

    Fixed drug eruption (FDE) causes cosmetic embarrassment in Nigerian patients, particularly when the characteristic hyperpigmented patches affect the face and lips. Drugs that have been implicated in the etiology of FDE, and the sites of lesions, may vary from country to country. Antimalarials, such as Fansidar, Fancimef, Maloxine, Amalar, and Metakelfin, were the most common offending agents, accounting for 38% of FDEs, followed by trimethoprim + sulfamethoxazole (co-trimoxazole) (28%), dipyrones (10%), Butazolidin (6%), thiacetazone (6%), metronidazole (4%), paracetamol (3%), and naproxen (3%). Lesions induced by the combination of sulfadoxine and pyrimethamine (in antimalarials) mainly involved the face and lips. In most cases, patients took these sulfa-containing antimalarials in combination with numerous other drugs, particularly analgesics. Unlike chloroquine-induced pruritus, which affects most Africans, the association between antimalarials and FDE has not been well documented in our region. Co-trimoxazole was associated more often than antimalarials with FDEs involving the mucocutaneous junctions of the genitalia and lips. Males with genital lesions on the glans penis represented 11 (48%) of those with co-trimoxazole hypersensitivity. The trunk and limbs were affected mainly by pyrazoles and Butazolidin, respectively; however, solitary lesions on the trunk were usually due to co-trimoxazole, whereas solitary lesions on the limbs were associated with Butazolidin.

  11. Updraft Fixed Bed Gasification Aspen Plus Model

    SciTech Connect

    2007-09-27

    The updraft fixed bed gasification model provides predictive modeling capabilities for updraft fixed bed gasifiers, when devolatilization data is available. The fixed bed model is constructed using Aspen Plus, process modeling software, coupled with a FORTRAN user kinetic subroutine. Current updraft gasification models created in Aspen Plus have limited predictive capabilities and must be "tuned" to reflect a generalized gas composition as specified in literature or by the gasifier manufacturer. This limits the applicability of the process model.

  12. 29 CFR 1917.118 - Fixed ladders.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... applies to all fixed ladders except: (1) Ladders forming an integral part of railway cars, highway..., microwave communications, electrical power and similar towers, poles and structures, including stacks...

  13. 29 CFR 1917.118 - Fixed ladders.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... applies to all fixed ladders except: (1) Ladders forming an integral part of railway cars, highway..., microwave communications, electrical power and similar towers, poles and structures, including stacks...

  14. NASA's Great Observatories May Unravel 400-Year Old Supernova Mystery

    NASA Astrophysics Data System (ADS)

    2004-10-01

    Four hundred years ago, sky watchers, including the famous astronomer Johannes Kepler, best known as the discoverer of the laws of planetary motion, were startled by the sudden appearance of a "new star" in the western sky, rivaling the brilliance of the nearby planets. Kepler's Supernova Remnant Multiple Images of Kepler's Supernova Remnant Modern astronomers, using NASA's three orbiting Great Observatories, are unraveling the mysteries of the expanding remains of Kepler's supernova, the last such object seen to explode in our Milky Way galaxy. When a new star appeared Oct. 9, 1604, observers could use only their eyes to study it. The telescope would not be invented for another four years. A team of modern astronomers has the combined abilities of NASA's Great Observatories, the Spitzer Space Telescope (SST), Hubble Space Telescope (HST), and Chandra X-ray Observatory, to analyze the remains in infrared radiation, visible light, and X-rays. Ravi Sankrit and William Blair of the Johns Hopkins University in Baltimore lead the team. The combined image unveils a bubble-shaped shroud of gas and dust, 14 light-years wide and expanding at 4 million mph. Observations from each telescope highlight distinct features of the supernova, a fast-moving shell of iron-rich material, surrounded by an expanding shock wave sweeping up interstellar gas and dust. Interview with Dr. Ravi Sankrit Interview with Dr. Ravi Sankrit "Multi-wavelength studies are absolutely essential for putting together a complete picture of how supernova remnants evolve," Sankrit said. Sankrit is an associate research scientist, Center for Astrophysical Sciences at Hopkins and lead for HST astronomer observations. "For instance, the infrared data are dominated by heated interstellar dust, while optical and X-ray observations sample different temperatures of gas," Blair added. Blair is a research professor, Physics and Astronomy Department at Hopkins and lead astronomer for SST observations. "A range of

  15. NASA's Great Observatories May Unravel 400-Year Old Supernova Mystery

    NASA Astrophysics Data System (ADS)

    2004-10-01

    Four hundred years ago, sky watchers, including the famous astronomer Johannes Kepler, best known as the discoverer of the laws of planetary motion, were startled by the sudden appearance of a "new star" in the western sky, rivaling the brilliance of the nearby planets. Kepler's Supernova Remnant Multiple Images of Kepler's Supernova Remnant Modern astronomers, using NASA's three orbiting Great Observatories, are unraveling the mysteries of the expanding remains of Kepler's supernova, the last such object seen to explode in our Milky Way galaxy. When a new star appeared Oct. 9, 1604, observers could use only their eyes to study it. The telescope would not be invented for another four years. A team of modern astronomers has the combined abilities of NASA's Great Observatories, the Spitzer Space Telescope (SST), Hubble Space Telescope (HST), and Chandra X-ray Observatory, to analyze the remains in infrared radiation, visible light, and X-rays. Ravi Sankrit and William Blair of the Johns Hopkins University in Baltimore lead the team. The combined image unveils a bubble-shaped shroud of gas and dust, 14 light-years wide and expanding at 4 million mph. Observations from each telescope highlight distinct features of the supernova, a fast-moving shell of iron-rich material, surrounded by an expanding shock wave sweeping up interstellar gas and dust. Interview with Dr. Ravi Sankrit Interview with Dr. Ravi Sankrit "Multi-wavelength studies are absolutely essential for putting together a complete picture of how supernova remnants evolve," Sankrit said. Sankrit is an associate research scientist, Center for Astrophysical Sciences at Hopkins and lead for HST astronomer observations. "For instance, the infrared data are dominated by heated interstellar dust, while optical and X-ray observations sample different temperatures of gas," Blair added. Blair is a research professor, Physics and Astronomy Department at Hopkins and lead astronomer for SST observations. "A range of

  16. The VLT Unravels the Nature of the Fastest Binary Star

    NASA Astrophysics Data System (ADS)

    2002-03-01

    Two Hot White Dwarfs Perform a Tight Dance Summary Observations with ESO's Very Large Telescope (VLT) in Chile and the Italian Telescopio Nazionale Galileo (TNG) on the Canary Islands during the past two years have enabled an international group of astronomers [1] to unravel the true nature of an exceptional binary stellar system. This system, designated RX J0806.3+1527 , was first discovered as an X-ray source of variable brightness - once every five minutes, it "switches off" for a short moment. The new observations have shown beyond doubt that this period reflects the orbital motion of two "white dwarf" stars that revolve around each other at a distance of only 80,000 km . Each of the stars is about as large as the Earth and this is the shortest orbital period known for any binary stellar system. The VLT spectrum displays lines of ionized helium, indicating that the presence of an exceedingly hot area on one of the stars - a "hot spot" with a temperature of approx. 250,000 degrees. The system is currently in a rarely seen, transitory evolutionary state . PR Photo 10a/02 : U- and R-band images of RX J0806.3+1527. PR Photo 10b/02 : Spectrum of RX J0806.3+1527 An amazing stellar binary system ESO PR Photo 10a/02 ESO PR Photo 10a/02 [Preview - JPEG: 800 x 400 pix - 440k] [Normal - JPEG: 1600 x 800 pix - 1.1M] Caption : PR Photo 10a/02 shows U and R filter images of the sky field around RX J0806.3+1527 (at centre of circle), obtained with the FORS2 multi-mode instrument on VLT KUEYEN. The object is brightest at the shorter wavelength (U-band) - reflecting its very high temperature. Technical information about the photo is available below. One year is the time it takes the Earth to move once around the Sun, our central star. This may seem quite fast when measured on the scale of the Universe, but this is a snail's motion compared to the the speed of two recently discovered stars. They revolve around each other 100,000 times faster; one full revolution takes only 321

  17. Unravelling the impact of inheritance within the Wilson Cycle: a combined mapping and numerical modelling approach

    NASA Astrophysics Data System (ADS)

    Chenin, Pauline; Manatschal, Gianreto; Lavier, Luc

    2015-04-01

    Our study aims to unravel how structural, lithological and thermal heterogeneities may influence both orogenic and rift systems within the Wilson Cycle. To do this, we map first-order rift structural domains, timing of the main rift events as well as major heterogeneities and structures inherited from previous orogenies. Besides, we design numerical modelling experiments to investigate the relationships highlighted from the comparison of these maps. We apply this approach to the North Atlantic region, which underwent two major orogenic phases during the Palaeozoic: (1) the Caledonian orogeny - now extending from United-Kingdom to northern Norway and Eastern Greenland - resulted from the Late Ordovician closure of the large Iapetus ocean (> 2 000 km) and smaller Tornquist Seaway. It was followed by purely mechanical extensional orogenic collapse; (2) the Variscides of Southwestern Europe were essentially built from the Devono-Carboniferous suturing of several small oceanic basins (< 200 km) in addition to the large Rheic Ocean. The subsequent orogenic collapse was accompanied by significant magmatic activity, which resulted in mafic underplating and associated mantle depletion over the whole orogenic area. Our study is twofolds: On the one hand, we investigate how the size and maturity of the intervening oceanic basins affect subduction and orogeny, considering two end-members: (a) immature oceanic basins defined as hyperextended rift systems that never achieved steady state seafloor spreading; and (b) mature oceans characterized by a self-sustained magmatic system forming homogeneous oceanic crust. On the other hand, we study how post-orogenic collapse-related underplating and associated mantle depletion may impact subsequent rifting depending on the thermal state (e.g. the duration of relaxation time between the magmatic episode and the onset of rifting). Our results highlight a very different behaviour of the North Atlantic rift with respect to the Caledonian and

  18. ON LYAPUNOV FAMILIES AROUND COLLINEAR LIBRATION POINTS

    SciTech Connect

    Hou, X. Y.; Liu, L.

    2009-06-15

    Evolution details of the planar and vertical Lyapunov families around the three collinear libration points in the restricted three-body problem were studied. Researches before were generally restricted to be within the colliding orbits with the primaries and for fixed mass parameters {mu}. In this paper, members after colliding orbits were computed. With increasing {mu}, how these families evolve was studied.

  19. Fixed-sample optimization using a probability density function

    SciTech Connect

    Barnett, R.N.; Sun, Zhiwei; Lester, W.A. Jr. |

    1997-12-31

    We consider the problem of optimizing parameters in a trial function that is to be used in fixed-node diffusion Monte Carlo calculations. We employ a trial function with a Boys-Handy correlation function and a one-particle basis set of high quality. By employing sample points picked from a positive definite distribution, parameters that determine the nodes of the trial function can be varied without introducing singularities into the optimization. For CH as a test system, we find that a trial function of high quality is obtained and that this trial function yields an improved fixed-node energy. This result sheds light on the important question of how to improve the nodal structure and, thereby, the accuracy of diffusion Monte Carlo.

  20. Fixed-Response Questions with a Difference.

    ERIC Educational Resources Information Center

    Johnstone, Alex H.; Ambusaidi, Abdullah

    2002-01-01

    Offers three types of fixed-response questions that are designed to overcome drawbacks appearing in the conventional forms of fixed-response questions such as not allowing the examiner to investigate reasoning, background, or prevent guessing. (Contains 14 references.) (Author/YDS)

  1. 29 CFR 1910.27 - Fixed ladders.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 5 2011-07-01 2011-07-01 false Fixed ladders. 1910.27 Section 1910.27 Labor Regulations... OCCUPATIONAL SAFETY AND HEALTH STANDARDS Walking-Working Surfaces § 1910.27 Fixed ladders. (a) Design requirements—(1) Design considerations. All ladders, appurtenances, and fastenings shall be designed to...

  2. 78 FR 20705 - Fixed Income Roundtable

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-05

    ... From the Federal Register Online via the Government Publishing Office SECURITIES AND EXCHANGE COMMISSION Fixed Income Roundtable AGENCY: Securities and Exchange Commission. ACTION: Notice of roundtable..., efficiency, and other aspects of fixed income markets. The roundtable will focus on the municipal...

  3. Gaining Insight into an Organization's Fixed Assets.

    ERIC Educational Resources Information Center

    Hardy, Elisabet

    2003-01-01

    Discusses issues related to school district implementation of June 2001 Government Accounting Standards Board (GASB) Statement 34 designed to change how schools report fixed assets. Includes planning for GASB implementation, conducting fixed-asset inventories, and making time for GASB reporting. (PKP)

  4. Negotiating a Fixed-Unit Price Contract.

    ERIC Educational Resources Information Center

    Pasquale, Mathew; Morrison, Wade

    1986-01-01

    Discusses the concept of "fixed-unit price contracting," an arrangement that is becoming popular with private industry councils (PICs). Guidelines include (1) find out as much as you can about the PIC's requirements; (2) figure out whether you can meet the PIC's requirements; and (3) keep in mind that most elements of a fixed-unit price contract…

  5. Unraveled mechanism in silk engineering: Fast reeling induced silk toughening

    NASA Astrophysics Data System (ADS)

    Wu, Xiang; Liu, Xiang-Yang; Du, Ning; Xu, Gangqin; Li, Baowen

    2009-08-01

    We theoretically and experimentally study the mechanical response of silkworm and spider silks against stretching and the relationship with the underlying structural factors. It is found that the typical stress-strain profiles are predicted in good agreement with experimental measurements by implementing the "β-sheet splitting" mechanism we discovered and verified, primarily varying the secondary structure of protein macromolecules. The functions of experimentally observed structural factors responding to the external stress have been clearly addressed, and optimization of the microscopic structures to enhance the mechanical strength will be pointed out, beneficial to their biomedical and textile applications.

  6. Spatial Correlation of Solar-Wind Turbulence from Two-Point Measurements

    NASA Technical Reports Server (NTRS)

    Matthaeus, W. H.; Milano, L. J.; Dasso, S.; Weygand, J. M.; Smith, C. W.; Kivelson, M. G.

    2005-01-01

    Interplanetary turbulence, the best studied case of low frequency plasma turbulence, is the only directly quantified instance of astrophysical turbulence. Here, magnetic field correlation analysis, using for the first time only proper two-point, single time measurements, provides a key step in unraveling the space-time structure of interplanetary turbulence. Simultaneous magnetic field data from the Wind, ACE, and Cluster spacecraft are analyzed to determine the correlation (outer) scale, and the Taylor microscale near Earth's orbit.

  7. Stimulus properties of fixed-interval responses.

    PubMed

    Buchman, I B; Zeiler, M D

    1975-11-01

    Responses in the first component of a chained schedule produced a change to the terminal component according to a fixed-interval schedule. The number of responses emitted in the fixed interval determined whether a variable-interval schedule of food presentation or extinction prevailed in the terminal component. In one condition, the variable-interval schedule was in effect only if the number of responses during the fixed interval was less than that specified; in another condition, the number of responses had to exceed that specified. The number of responses emitted in the fixed interval did not shift markedly in the direction required for food presentation. Instead, responding often tended to change in the opposite direction. Such an effect indicated that differential food presentation did not modify the reference behavior in accord with the requirement, but it was consistent with other data on fixed-interval schedule performance. Behavior in the terminal component, however, did reveal sensitivity to the relation between total responses emitted in the fixed interval and the availability of food. Response rate in the terminal component was a function of the proximity of the response number emitted in the fixed interval to that required for food presentation. Thus, response number served as a discriminative stimulus controlling subsequent performance.

  8. Enhancing vitamin E in oilseeds: unraveling tocopherol and tocotrienol biosynthesis.

    PubMed

    Hunter, Sarah C; Cahoon, Edgar B

    2007-03-01

    Naturally occurring vitamin E, comprised of four forms each of tocopherols and tocotrienols, are synthesized solely by photosynthetic organisms and function primarily as antioxidants. These different forms vary in their biological availability and in their physiological and chemical activities. Tocopherols and tocotrienols play important roles in the oxidative stability of vegetable oils and in the nutritional quality of crop plants for human and livestock diets. The isolation of genes for nearly all the steps in tocopherol and tocotrienol biosynthesis has facilitated efforts to alter metabolic flux through these pathways in plant cells. Herein we review the recent work done in the field, focusing on branch points and metabolic engineering to enhance and alter vitamin E content and composition in oilseed crops.

  9. Metagenomics meets time series analysis: unraveling microbial community dynamics.

    PubMed

    Faust, Karoline; Lahti, Leo; Gonze, Didier; de Vos, Willem M; Raes, Jeroen

    2015-06-01

    The recent increase in the number of microbial time series studies offers new insights into the stability and dynamics of microbial communities, from the world's oceans to human microbiota. Dedicated time series analysis tools allow taking full advantage of these data. Such tools can reveal periodic patterns, help to build predictive models or, on the contrary, quantify irregularities that make community behavior unpredictable. Microbial communities can change abruptly in response to small perturbations, linked to changing conditions or the presence of multiple stable states. With sufficient samples or time points, such alternative states can be detected. In addition, temporal variation of microbial interactions can be captured with time-varying networks. Here, we apply these techniques on multiple longitudinal datasets to illustrate their potential for microbiome research.

  10. Unraveling the Labyrinth of Star Formation with Herschel

    NASA Astrophysics Data System (ADS)

    André, Philippe; Könyves, Vera; Arzoumanian, Doris; Palmeirim, Pedro

    Recent studies of nearby interstellar clouds with the Herschel Space Observatory have provided us with unprecedented images of the initial conditions and early phases of the star formation process. The Herschel images point to the central role of filaments in star formation and to their likely connection to interstellar turbulence. Overall, the Herschel results suggest that it may be possible to understand both the IMF and the global rate of star formation in galaxies by studying the physics of how dense structures (e.g. filaments, cores) form and grow in the ISM of our own Galaxy. Despite an apparent complexity, global star formation may be governed by relatively simple universal laws from filament to galactic scales.

  11. Updraft Fixed Bed Gasification Aspen Plus Model

    2007-09-27

    The updraft fixed bed gasification model provides predictive modeling capabilities for updraft fixed bed gasifiers, when devolatilization data is available. The fixed bed model is constructed using Aspen Plus, process modeling software, coupled with a FORTRAN user kinetic subroutine. Current updraft gasification models created in Aspen Plus have limited predictive capabilities and must be "tuned" to reflect a generalized gas composition as specified in literature or by the gasifier manufacturer. This limits the applicability ofmore » the process model.« less

  12. The 1994 Fermilab Fixed Target Program

    SciTech Connect

    Conrad, J. |

    1994-11-01

    This paper highlights the results of the Fermilab Fixed Target Program that were announced between October, 1993 and October, 1994. These results are drawn from 18 experiments that took data in the 1985, 1987 and 1990/91 fixed target running periods. For this discussion, the Fermilab Fixed Target Program is divided into 5 major topics: hadron structure, precision electroweak measurements, heavy quark production, polarization and magnetic moments, and searches for new phenomena. However, it should be noted that most experiments span several subtopics. Also, measurements within each subtopic often affect the results in other subtopics. For example, parton distributions from hadron structure measurements are used in the studies of heavy quark production.

  13. [FIXED COMBINATION ATORVASTATIN-EZETIMIBE (ATOZET®)].

    PubMed

    Scheen, A J

    2016-01-01

    Cardiovascular prevention in subjects at high or very high risk requires a drastic reduction in LDL cholesterol according to the concept "the lower, the better". The combination of an inhibitor of cholesterol synthesis and a selective inhibitor of intestinal absorption results in a complementary and synergistic LDL-lowering activity. Besides a first fixed combination ezetimibe-simvastatin (Inegy®), a new fixed combination is presented, Atozet® that combines atorvastatin and ezetimibe. Because atorvastatin is more potent than simvastatin, this novel fixed combination should facilitate reaching therapeutic goals in terms of LDL cholesterol amongst patients with severe hypercholesterolaemia and/or at high or very high cardiovascular risk.

  14. The VLT Unravels the Nature of the Fastest Binary Star

    NASA Astrophysics Data System (ADS)

    2002-03-01

    Two Hot White Dwarfs Perform a Tight Dance Summary Observations with ESO's Very Large Telescope (VLT) in Chile and the Italian Telescopio Nazionale Galileo (TNG) on the Canary Islands during the past two years have enabled an international group of astronomers [1] to unravel the true nature of an exceptional binary stellar system. This system, designated RX J0806.3+1527 , was first discovered as an X-ray source of variable brightness - once every five minutes, it "switches off" for a short moment. The new observations have shown beyond doubt that this period reflects the orbital motion of two "white dwarf" stars that revolve around each other at a distance of only 80,000 km . Each of the stars is about as large as the Earth and this is the shortest orbital period known for any binary stellar system. The VLT spectrum displays lines of ionized helium, indicating that the presence of an exceedingly hot area on one of the stars - a "hot spot" with a temperature of approx. 250,000 degrees. The system is currently in a rarely seen, transitory evolutionary state . PR Photo 10a/02 : U- and R-band images of RX J0806.3+1527. PR Photo 10b/02 : Spectrum of RX J0806.3+1527 An amazing stellar binary system ESO PR Photo 10a/02 ESO PR Photo 10a/02 [Preview - JPEG: 800 x 400 pix - 440k] [Normal - JPEG: 1600 x 800 pix - 1.1M] Caption : PR Photo 10a/02 shows U and R filter images of the sky field around RX J0806.3+1527 (at centre of circle), obtained with the FORS2 multi-mode instrument on VLT KUEYEN. The object is brightest at the shorter wavelength (U-band) - reflecting its very high temperature. Technical information about the photo is available below. One year is the time it takes the Earth to move once around the Sun, our central star. This may seem quite fast when measured on the scale of the Universe, but this is a snail's motion compared to the the speed of two recently discovered stars. They revolve around each other 100,000 times faster; one full revolution takes only 321

  15. Unravelling and controlling hidden imprint fields in ferroelectric capacitors.

    PubMed

    Liu, Fanmao; Fina, Ignasi; Bertacco, Riccardo; Fontcuberta, Josep

    2016-04-28

    Ferroelectric materials have a spontaneous polarization that can point along energetically equivalent, opposite directions. However, when ferroelectric layers are sandwiched between different metallic electrodes, asymmetric electrostatic boundary conditions may induce the appearance of an electric field (imprint field, Eimp) that breaks the degeneracy of the polarization directions, favouring one of them. This has dramatic consequences on functionality of ferroelectric-based devices such as ferroelectric memories or photodetectors. Therefore, to cancel out the Eimp, ferroelectric components are commonly built using symmetric contact configuration. Indeed, in this symmetric contact configuration, when measurements are done under time-varying electric fields of relatively low frequency, an archetypical symmetric single-step switching process is observed, indicating Eimp ≈ 0. However, we report here on the discovery that when measurements are performed at high frequency, a well-defined double-step switching is observed, indicating the presence of Eimp. We argue that this frequency dependence originates from short-living head-to-head or tail-to-tail ferroelectric capacitors in the device. We demonstrate that we can modulate Eimp and the life-time of head-to-head or tail-to-tail polarization configurations by adjusting the polarization screening charges by suitable illumination. These findings are of relevance to understand the effects of internal electric fields on pivotal ferroelectric properties, such as memory retention and photoresponse.

  16. Unravelling and controlling hidden imprint fields in ferroelectric capacitors

    NASA Astrophysics Data System (ADS)

    Liu, Fanmao; Fina, Ignasi; Bertacco, Riccardo; Fontcuberta, Josep

    2016-04-01

    Ferroelectric materials have a spontaneous polarization that can point along energetically equivalent, opposite directions. However, when ferroelectric layers are sandwiched between different metallic electrodes, asymmetric electrostatic boundary conditions may induce the appearance of an electric field (imprint field, Eimp) that breaks the degeneracy of the polarization directions, favouring one of them. This has dramatic consequences on functionality of ferroelectric-based devices such as ferroelectric memories or photodetectors. Therefore, to cancel out the Eimp, ferroelectric components are commonly built using symmetric contact configuration. Indeed, in this symmetric contact configuration, when measurements are done under time-varying electric fields of relatively low frequency, an archetypical symmetric single-step switching process is observed, indicating Eimp ≈ 0. However, we report here on the discovery that when measurements are performed at high frequency, a well-defined double-step switching is observed, indicating the presence of Eimp. We argue that this frequency dependence originates from short-living head-to-head or tail-to-tail ferroelectric capacitors in the device. We demonstrate that we can modulate Eimp and the life-time of head-to-head or tail-to-tail polarization configurations by adjusting the polarization screening charges by suitable illumination. These findings are of relevance to understand the effects of internal electric fields on pivotal ferroelectric properties, such as memory retention and photoresponse.

  17. Unraveling the nature of interaction between substituted phenol and amiodarone.

    PubMed

    Hassan, Walid M I; Abo Dena, Ahmed S

    2014-02-01

    A comprehensive study of the interaction between nitrophenols (π-acceptors) and amiodarone (AM) was performed using electronic absorption spectra. The key point is to clarify the erroneous interpretation of the interaction between nitrophenols and one of the basic organic drugs. Matching of the experimental UV-vis spectra and the theoretical ones obtained by DFT calculations revealed that the tertiary amino group of AM reacts with the phenol compounds under investigation via proton-transfer but not charge-transfer (C.T.) mechanisms, unlike what is commonly known about this type of interaction. The interaction was carried out in solutions of different basic pH values to study the effect of hydrogen ion concentration on the reaction. The results show that the reaction is a simple acid-base reaction. As a result, this reaction cannot be used by analytical chemists for determination of one of the studied compounds due to its very low selectivity. TD-DFT as well as geometry optimization of the nitrophenols were calculated with the B3LYP functional, using aug-cc-pvDZ and LanL2DZ as basis sets for ionic and neutral compounds, respectively. The theoretical spectra of possible interactions between AM and nitrophenols result in the same spectra of ionized nitrophenols alone, indicating no possibility for the formation of charge-transfer complexes. PMID:24428617

  18. Unravelling and controlling hidden imprint fields in ferroelectric capacitors

    PubMed Central

    Liu, Fanmao; Fina, Ignasi; Bertacco, Riccardo; Fontcuberta, Josep

    2016-01-01

    Ferroelectric materials have a spontaneous polarization that can point along energetically equivalent, opposite directions. However, when ferroelectric layers are sandwiched between different metallic electrodes, asymmetric electrostatic boundary conditions may induce the appearance of an electric field (imprint field, Eimp) that breaks the degeneracy of the polarization directions, favouring one of them. This has dramatic consequences on functionality of ferroelectric-based devices such as ferroelectric memories or photodetectors. Therefore, to cancel out the Eimp, ferroelectric components are commonly built using symmetric contact configuration. Indeed, in this symmetric contact configuration, when measurements are done under time-varying electric fields of relatively low frequency, an archetypical symmetric single-step switching process is observed, indicating Eimp ≈ 0. However, we report here on the discovery that when measurements are performed at high frequency, a well-defined double-step switching is observed, indicating the presence of Eimp. We argue that this frequency dependence originates from short-living head-to-head or tail-to-tail ferroelectric capacitors in the device. We demonstrate that we can modulate Eimp and the life-time of head-to-head or tail-to-tail polarization configurations by adjusting the polarization screening charges by suitable illumination. These findings are of relevance to understand the effects of internal electric fields on pivotal ferroelectric properties, such as memory retention and photoresponse. PMID:27122309

  19. Unravelling and controlling hidden imprint fields in ferroelectric capacitors.

    PubMed

    Liu, Fanmao; Fina, Ignasi; Bertacco, Riccardo; Fontcuberta, Josep

    2016-01-01

    Ferroelectric materials have a spontaneous polarization that can point along energetically equivalent, opposite directions. However, when ferroelectric layers are sandwiched between different metallic electrodes, asymmetric electrostatic boundary conditions may induce the appearance of an electric field (imprint field, Eimp) that breaks the degeneracy of the polarization directions, favouring one of them. This has dramatic consequences on functionality of ferroelectric-based devices such as ferroelectric memories or photodetectors. Therefore, to cancel out the Eimp, ferroelectric components are commonly built using symmetric contact configuration. Indeed, in this symmetric contact configuration, when measurements are done under time-varying electric fields of relatively low frequency, an archetypical symmetric single-step switching process is observed, indicating Eimp ≈ 0. However, we report here on the discovery that when measurements are performed at high frequency, a well-defined double-step switching is observed, indicating the presence of Eimp. We argue that this frequency dependence originates from short-living head-to-head or tail-to-tail ferroelectric capacitors in the device. We demonstrate that we can modulate Eimp and the life-time of head-to-head or tail-to-tail polarization configurations by adjusting the polarization screening charges by suitable illumination. These findings are of relevance to understand the effects of internal electric fields on pivotal ferroelectric properties, such as memory retention and photoresponse. PMID:27122309

  20. Event Display for the Fixed Target Experiment BM@N

    NASA Astrophysics Data System (ADS)

    Gertsenberger, Konstantin

    2016-02-01

    One of the main problems to be solved in modern high energy physics experiments on particle collisions with a fixed target is the visual representation of the events during the experiment run. The article briefly describes the structure of the BM@N facility at the Nuclotron being under construction at the Joint Institute for Nuclear Research with the aim to study properties of the baryonic matter in collisions of ions with fixed target at energies up to 4 GeV/nucleon (for Au79+). Aspects concerning the visualization of data and detector details at the modern experiments and possibilities of practical applications are discussed. We present event display system intended to visualize the detector geometries and events of particle collisions with the fixed target, its options and features as well as integration with BMNRoot software. The examples of graphical representation of simulated and reconstructed points and particle tracks with BM@N geometry are given for central collisions of Au79+ ions with gold target and deuterons with carbon target.

  1. Applications of fixed-time flow cytometry in cell biology

    NASA Astrophysics Data System (ADS)

    Tarnok, Attila

    1998-04-01

    Flow cytometric (FCM) measurement of intracellular free calcium [Ca2+]i, transients is usually done by two methods: (a) after a short prerun period to assess the baseline the measurement is stopped, stimulus is added and the measurement continued or (b) stimulus is injected during measurement and the sample pressure briefly increased to deliver cells rapidly to the detection point. In (a) measurement of very short transients [Ca2+]i is impeded by the lag time between stimulus addition and restart of acquisition. In (b) response of pressure sensitive cells is hard to analyze. Furthermore, (a) and (b) do not allow to quantify and sort rare responders. A simple Fixed- Time device has been developed. Ca2+ sensitive fluorescent dye labeled cells and a stimulus are placed in different vials. Both fluids are forced by the same pressure through tubing that merges into a T-junction where they mix and are delivered through a connecting tube to the FCM: [Ca2+]i is measured at a certain time after stimulation that is adjusted by sample flow rate and length of the connecting tube. With Fixed-Time, the pressure sensitive neuronal NH15-CA2 cell was analyzed. Furthermore, rare neurotransmitter responsive fibroblast from normal and transfected cultures were sorted and cloned and their dose response characterized. The results demonstrate that fixed- time FCM is an important tool for the analysis of the cells physiology and the preparation of responders.

  2. Stabilising Springs for Fixed Lingual Retainer

    PubMed Central

    Karthikeyan, M.K.; Ramachandraprabhakar; Saravanan, R.; Rajvikram, N.; Kuppuchamy

    2013-01-01

    Most treated malocclusion needs fixed lingual retention. To stabilise fixed lingual retainer in the exact location needs proper stabilisation. Proper stabilization requires a holding spring. This Stabilising Spring should be easy to fabricate and help the clinician to stabilise the retainer quickly and save the chair side time. More over it should not irritate the mucosa and should be easy to insert and remove. PMID:24392431

  3. DNA extraction from formalin-fixed material.

    PubMed

    Campos, Paula F; Gilbert, Thomas M P

    2012-01-01

    The principal challenges facing PCR-based analyses of DNA extracted from formalin-fixed materials are fragmentation of the DNA and cross-linked protein-DNA complexes. Here, we present an efficient protocol to extract DNA from formalin-fixed or paraffin-embedded tissues (FFPE). In this protocol, protein-DNA cross-links are reversed using heat and alkali treatment, yielding significantly longer fragments and larger amounts of PCR-amplifiable DNA than standard DNA extraction protocols.

  4. Fixed-target physics at Fermilab

    SciTech Connect

    Bjorken, J.D.

    1985-03-01

    The Fermilab Energy Saver is now successfully commissioned and fixed-target experimentation at high energy (800 GeV) has begun. In addition, a number of new experiments designed to exploit the unique features of the Tevatron are yet to come on-line. In this talk, we will review recent accomplishments in the fixed-target program and describe experiments in progress and others yet to come.

  5. Regulation of the fixA gene and fixBC operon in Bradyrhizobium japonicum.

    PubMed Central

    Gubler, M; Hennecke, H

    1988-01-01

    The transcriptional start site of the Bradyrhizobium japonicum fixBC operon was identified by nuclease S1 mapping. It was located approximately 700 base pairs upstream of fixB and was preceded by a promoter sequence that showed strong homology to the B. japonicum fixA promoter and thus to the general nif consensus promoter sequence. Further transcript mapping experiments revealed that fixA and fixBC transcription in B. japonicum strictly depended on the presence of the regulatory gene nifA and on low oxygen partial pressure. Consistent with these data, chromosomally integrated fixA- and fixB-lacZ fusions expressed beta-galactosidase activity only in the wild type but not in a nifA mutant and only under microaerobic but not aerobic growth conditions. The presence of nifA accounted for a 19-fold and 44-fold activation of the fixA and fixB promoters, respectively. These results show that the fixA and fixBC genes are regulated in a way similar to that of the nitrogenase genes nifH and nifDK. A very peculiar finding was that the fixA and fixB promoters, when they were located on plasmids, could hardly be activated by the NifA protein, irrespective of whether this was tested in Escherichia coli or B. japonicum backgrounds. This is in clear contrast to the situation with nifH and nifD promoters. Images PMID:3343218

  6. Unravelling The Chemical History Of The Solar Neighborhood With Giants

    NASA Astrophysics Data System (ADS)

    Feuillet, Diane; Holtzman, Jon A.; Girardi, Leo; Apogee Team

    2015-01-01

    In the age of high-resolution spectroscopic surveys, elemental abundance measurements for large samples of stars allow us to identify individual populations within the Milky Way disk, however; absolute age measurements are needed to put the evolution of the stellar disk populations in a Galactic context. We present a sample of 700 local (d <400 pc) red giant stars observed using the New Mexico State University 1m telescope with the SDSS-III Apache Point Observatory Galactic Evolution Experiment (APOGEE) spectrograph, for which we estimate ages from the high-resolution spectroscopic stellar parameters and accurate distance measurements from Hipparcos. The high-resolution (R ˜ 23,000), near infrared (H-band, 1.5-1.7 μ m) APOGEE spectra provide measurements of the stellar atmospheric parameters (temperature, surface gravity, and overall metallicity), as well as abundances of 15 individual elements. Due to the smaller uncertainties in surface gravity possible with high-resolution spectra and accurate Hipparcos distance measurements, we are able to calculate the masses of our stars to within 40%. We target giants because the relatively rapid evolution of stars up the red giant branch allows an age to be estimated based on the mass using a mass-age relation of evolved stars from model isochrones. Using these age estimates and the APOGEE abundances, we examine the abundance trends of individual elements with age in the solar neighborhood. As with other recent surveys of disk stars, we find older stars to be enhanced in α-elements, while younger stars have solar α-abundances. We find a flat age-metallicity relation with a large spread in metallicity at a given age, however; we note that our sample lacks metal-poor stars. This method of estimating ages of red giants is developed with the intent of estimating ages for the much larger sample of >10,000 APOGEE survey giants that will have parallax measurements from Gaia.

  7. 48 CFR 16.204 - Fixed-price incentive contracts.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Fixed-price incentive... CONTRACTING METHODS AND CONTRACT TYPES TYPES OF CONTRACTS Fixed-Price Contracts 16.204 Fixed-price incentive contracts. A fixed-price incentive contract is a fixed-price contract that provides for adjusting profit...

  8. 48 CFR 16.204 - Fixed-price incentive contracts.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Fixed-price incentive... CONTRACTING METHODS AND CONTRACT TYPES TYPES OF CONTRACTS Fixed-Price Contracts 16.204 Fixed-price incentive contracts. A fixed-price incentive contract is a fixed-price contract that provides for adjusting profit...

  9. 48 CFR 16.204 - Fixed-price incentive contracts.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Fixed-price incentive... CONTRACTING METHODS AND CONTRACT TYPES TYPES OF CONTRACTS Fixed-Price Contracts 16.204 Fixed-price incentive contracts. A fixed-price incentive contract is a fixed-price contract that provides for adjusting profit...

  10. 48 CFR 16.204 - Fixed-price incentive contracts.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Fixed-price incentive... CONTRACTING METHODS AND CONTRACT TYPES TYPES OF CONTRACTS Fixed-Price Contracts 16.204 Fixed-price incentive contracts. A fixed-price incentive contract is a fixed-price contract that provides for adjusting profit...

  11. 48 CFR 16.204 - Fixed-price incentive contracts.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Fixed-price incentive... CONTRACTING METHODS AND CONTRACT TYPES TYPES OF CONTRACTS Fixed-Price Contracts 16.204 Fixed-price incentive contracts. A fixed-price incentive contract is a fixed-price contract that provides for adjusting profit...

  12. Optical simulation for a fixed spherical solar collector.

    PubMed

    Authier, B; Hill, L; Duban, M; Trarieux, P; Sarazin, M; Nadeau, P

    1979-09-15

    To calculate the absorber dimensions for a fixed spherical solar collector, an optical simulation of the raytracing type is proposed. The physical quantities, which have an effect upon these dimensions, are described as well as the measurement methods. Once the dimensions are determined, the incident flux on the absorber surface can be calculated by the same program in terms of different zenith distances. These calculations can be checked by comparing the calculated flux on the surface of the absorber with the measured flux at different points along the absorber aimed at the full moon instead of at the sun. Through the data obtained from the measurements, fluctuating points of high flux and permanent zones which receive double and triple reflection rays have been studied. PMID:20212809

  13. Vibrational spectroscopy studies of formalin-fixed cervix tissues.

    PubMed

    Krishna, C M; Sockalingum, G D; Vadhiraja, B M; Maheedhar, K; Rao, A C K; Rao, L; Venteo, L; Pluot, M; Fernandes, D J; Vidyasagar, M S; Kartha, V B; Manfait, M

    2007-02-15

    Optical histopathology is fast emerging as a potential tool in cancer diagnosis. Fresh tissues in saline are ideal samples for optical histopathology. However, evaluation of suitability of ex vivo handled tissues is necessitated because of severe constraints in sample procurement, handling, and other associated problems with fresh tissues. Among these methods, formalin-fixed samples are shown to be suitable for optical histopathology. However, it is necessary to further evaluate this method from the point of view discriminating tissues with minute biochemical variations. A pilot Raman and Fourier transform infrared (FTIR) microspectroscopic studies of formalin-fixed tissues normal, malignant, and after-2-fractions of radiotherapy from the same malignant cervix subjects were carried out, with an aim to explore the feasibility of discriminating these tissues, especially the tissues after-2-fractions of radiotherapy from other two groups. Raman and FTIR spectra exhibit large differences for normal and malignant tissues and subtle differences are seen between malignant and after-2-fractions of radiotherapy tissues. Spectral data were analyzed by principal component analysis (PCA) and it provided good discrimination of normal and malignant tissues. PCA of data of three tissues, normal, malignant, and 2-fractions after radiotherapy, gave two clusters corresponding to normal and malignant + after-2-fractions of radiotherapy tissues. A second step of PCA was required to achieve discrimination between malignant and after-2-fractions of radiotherapy tissues. Hence, this study not only further supports the use of formalin-fixed tissues in optical histopathology, especially from Raman spectroscopy point of view, it also indicates feasibility of discriminating tissues with minute biochemical differences such as malignant and after-2-fractions of radiotherapy.

  14. Combined Label-Free Quantitative Proteomics and microRNA Expression Analysis of Breast Cancer Unravel Molecular Differences with Clinical Implications.

    PubMed

    Gámez-Pozo, Angelo; Berges-Soria, Julia; Arevalillo, Jorge M; Nanni, Paolo; López-Vacas, Rocío; Navarro, Hilario; Grossmann, Jonas; Castaneda, Carlos A; Main, Paloma; Díaz-Almirón, Mariana; Espinosa, Enrique; Ciruelos, Eva; Fresno Vara, Juan Ángel

    2015-06-01

    Better knowledge of the biology of breast cancer has allowed the use of new targeted therapies, leading to improved outcome. High-throughput technologies allow deepening into the molecular architecture of breast cancer, integrating different levels of information, which is important if it helps in making clinical decisions. microRNA (miRNA) and protein expression profiles were obtained from 71 estrogen receptor-positive (ER(+)) and 25 triple-negative breast cancer (TNBC) samples. RNA and proteins obtained from formalin-fixed, paraffin-embedded tumors were analyzed by RT-qPCR and LC/MS-MS, respectively. We applied probabilistic graphical models representing complex biologic systems as networks, confirming that ER(+) and TNBC subtypes are distinct biologic entities. The integration of miRNA and protein expression data unravels molecular processes that can be related to differences in the genesis and clinical evolution of these types of breast cancer. Our results confirm that TNBC has a unique metabolic profile that may be exploited for therapeutic intervention. PMID:25883093

  15. Controlling Cyanobacterial Blooms in Hypertrophic Lake Taihu, China: Will Nitrogen Reductions Cause Replacement of Non-N2 Fixing by N2 Fixing Taxa?

    PubMed Central

    Paerl, Hans W.; Xu, Hai; Hall, Nathan S.; Zhu, Guangwei; Qin, Boqiang; Wu, Yali; Rossignol, Karen L.; Dong, Linghan; McCarthy, Mark J.; Joyner, Alan R.

    2014-01-01

    Excessive anthropogenic nitrogen (N) and phosphorus (P) inputs have caused an alarming increase in harmful cyanobacterial blooms, threatening sustainability of lakes and reservoirs worldwide. Hypertrophic Lake Taihu, China’s third largest freshwater lake, typifies this predicament, with toxic blooms of the non-N2 fixing cyanobacteria Microcystis spp. dominating from spring through fall. Previous studies indicate N and P reductions are needed to reduce bloom magnitude and duration. However, N reductions may encourage replacement of non-N2 fixing with N2 fixing cyanobacteria. This potentially counterproductive scenario was evaluated using replicate, large (1000 L), in-lake mesocosms during summer bloom periods. N+P additions led to maximum phytoplankton production. Phosphorus enrichment, which promoted N limitation, resulted in increases in N2 fixing taxa (Anabaena spp.), but it did not lead to significant replacement of non-N2 fixing with N2 fixing cyanobacteria, and N2 fixation rates remained ecologically insignificant. Furthermore, P enrichment failed to increase phytoplankton production relative to controls, indicating that N was the most limiting nutrient throughout this period. We propose that Microcystis spp. and other non-N2 fixing genera can maintain dominance in this shallow, highly turbid, nutrient-enriched lake by outcompeting N2 fixing taxa for existing sources of N and P stored and cycled in the lake. To bring Taihu and other hypertrophic systems below the bloom threshold, both N and P reductions will be needed until the legacy of high N and P loading and sediment nutrient storage in these systems is depleted. At that point, a more exclusive focus on P reductions may be feasible. PMID:25405474

  16. 30 CFR 57.11026 - Protection for inclined fixed ladders.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Protection for inclined fixed ladders. 57.11026... and Escapeways Travelways-Surface Only § 57.11026 Protection for inclined fixed ladders. Fixed ladders... ladders....

  17. 30 CFR 57.11026 - Protection for inclined fixed ladders.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Protection for inclined fixed ladders. 57.11026... and Escapeways Travelways-Surface Only § 57.11026 Protection for inclined fixed ladders. Fixed ladders... ladders....

  18. Melting point, boiling point, and symmetry.

    PubMed

    Abramowitz, R; Yalkowsky, S H

    1990-09-01

    The relationship between the melting point of a compound and its chemical structure remains poorly understood. The melting point of a compound can be related to certain of its other physical chemical properties. The boiling point of a compound can be determined from additive constitutive properties, but the melting point can be estimated only with the aid of nonadditive constitutive parameters. The melting point of some non-hydrogen-bonding, rigid compounds can be estimated by the equation MP = 0.772 * BP + 110.8 * SIGMAL + 11.56 * ORTHO + 31.9 * EXPAN - 240.7 where MP is the melting point of the compound in Kelvin, BP is the boiling point, SIGMAL is the logarithm of the symmetry number, EXPAN is the cube of the eccentricity of the compound, and ORTHO indicates the number of groups that are ortho to another group.

  19. The Hilbert scheme of points for supersingular abelian surfaces

    NASA Astrophysics Data System (ADS)

    Schröer, Stefan

    2009-04-01

    We study the geometry of Hilbert schemes of points on abelian surfaces and Beauville’s generalized Kummer varieties in positive characteristics. The main result is that, in characteristic two, the addition map from the Hilbert scheme of two points to the abelian surface is a quasifibration such that all fibers are nonsmooth. In particular, the corresponding generalized Kummer surface is nonsmooth, and minimally elliptic singularities occur in the supersingular case. We unravel the structure of the singularities in dependence of p-rank and a-number of the abelian surface. To do so, we establish a McKay Correspondence for Artin’s wild involutions on surfaces. Along the line, we find examples of canonical singularities that are not rational singularities.

  20. Unraveling the complexities of disaster management: a framework for critical social infrastructure to promote population health and resilience.

    PubMed

    O'Sullivan, Tracey L; Kuziemsky, Craig E; Toal-Sullivan, Darene; Corneil, Wayne

    2013-09-01

    Complexity is a useful frame of reference for disaster management and understanding population health. An important means to unraveling the complexities of disaster management is to recognize the interdependencies between health care and broader social systems and how they intersect to promote health and resilience before, during and after a crisis. While recent literature has expanded our understanding of the complexity of disasters at the macro level, few studies have examined empirically how dynamic elements of critical social infrastructure at the micro level influence community capacity. The purpose of this study was to explore empirically the complexity of disasters, to determine levers for action where interventions can be used to facilitate collaborative action and promote health among high risk populations. A second purpose was to build a framework for critical social infrastructure and develop a model to identify potential points of intervention to promote population health and resilience. A community-based participatory research design was used in nine focus group consultations (n = 143) held in five communities in Canada, between October 2010 and March 2011, using the Structured Interview Matrix facilitation technique. The findings underscore the importance of interconnectedness of hard and soft systems at the micro level, with culture providing the backdrop for the social fabric of each community. Open coding drawing upon the tenets of complexity theory was used to develop four core themes that provide structure for the framework that evolved; they relate to dynamic context, situational awareness and connectedness, flexible planning, and collaboration, which are needed to foster adaptive responses to disasters. Seven action recommendations are presented, to promote community resilience and population health.

  1. Pigeons' choices in situations of diminishing returns: fixed- versus progressive-ratio schedules.

    PubMed

    Wanchisen, B A; Tatham, T A; Hineline, P N

    1988-11-01

    In two different discrete-trial procedures, pigeons were faced with choices between fixed-ratio and progressive-ratio schedules. The latter schedules entail diminishing returns, a feature analogous to foraging situations in the wild. In the first condition (no reset), subjects chose between a progressive-ratio schedule that increased in increments of 20 throughout a session and a fixed-ratio schedule that was constant across blocks of sessions. The size of the fixed ratio was varied parametrically through an ascending and then a descending series. In the reset condition, the same fixed-ratio values were used, but each selection (and completion) of the fixed ratio reset the progressive-ratio schedule back to its minimal value. In the no-reset procedure, the pigeons tended to cease selecting the progressive ratio when it equaled or slightly exceeded the fixed-ratio value, whereas in reset, they chose the fixed ratio well in advance of that equality point. These results indicate sensitivity to molar as well as to molecular reinforcement rates, and those molar relationships are similar to predictions based on the marginal value theorem of optimal foraging theory (e.g., Charnov, 1976). However, although previous results with monkeys (Hineline & Sodetz, 1987) appeared to minimize responses per reinforcement, the present results corresponded more closely to predictions based on sums-of-reciprocals of distance from point of choice to each of the next four reinforcers. Results obtained by Hodos and Trumbule (1967) with chimpanzees in a similar procedure were intermediate between these two relationships. Variability of choices, as well as median choice points, differed between the reset and no-reset conditions.(ABSTRACT TRUNCATED AT 250 WORDS)

  2. Unravelling Thiol's Role in Directing Asymmetric Growth of Au Nanorod-Au Nanoparticle Dimers.

    PubMed

    Huang, Jianfeng; Zhu, Yihan; Liu, Changxu; Shi, Zhan; Fratalocchi, Andrea; Han, Yu

    2016-01-13

    Asymmetric nanocrystals have practical significance in nanotechnologies but present fundamental synthetic challenges. Thiol ligands have proven effective in breaking the symmetric growth of metallic nanocrystals but their exact roles in the synthesis remain elusive. Here, we synthesized an unprecedented Au nanorod-Au nanoparticle (AuNR-AuNP) dimer structure with the assistance of a thiol ligand. On the basis of our experimental observations, we unraveled for the first time that the thiol could cause an inhomogeneous distribution of surface strains on the seed crystals as well as a modulated reduction rate of metal precursors, which jointly induced the asymmetric growth of monometallic dimers.

  3. Carbon-Fixing Reactions of Photosynthesis.

    PubMed

    2016-07-01

    Summaryplantcell;28/7/tpc.116.tt0716/FIG1F1fig1Photosynthesis in plants converts the energy of sunlight into chemical energy. Although photosynthesis involves many proteins and catalytic processes, it often is described as two sets of reactions, the light-dependent reactions and the carbon-fixing reactions. This lesson introduces the core biochemistry of the carbon-fixing reactions of photosynthesis, as well as its variations, C4 and CAM. Finally, it addresses how and why plants are affected by rising atmospheric CO2 levels, and research efforts to increase photosynthetic efficiency in current and future conditions.

  4. Carbon-Fixing Reactions of Photosynthesis.

    PubMed

    2016-07-01

    Summaryplantcell;28/7/tpc.116.tt0716/FIG1F1fig1Photosynthesis in plants converts the energy of sunlight into chemical energy. Although photosynthesis involves many proteins and catalytic processes, it often is described as two sets of reactions, the light-dependent reactions and the carbon-fixing reactions. This lesson introduces the core biochemistry of the carbon-fixing reactions of photosynthesis, as well as its variations, C4 and CAM. Finally, it addresses how and why plants are affected by rising atmospheric CO2 levels, and research efforts to increase photosynthetic efficiency in current and future conditions. PMID:27493209

  5. Reading with fixed and variable character pitch.

    PubMed

    Arditi, A; Knoblauch, K; Grunwald, I

    1990-10-01

    We compared the effects of fixed and variable (proportional) spacing on reading speeds and found variable pitch to yield better performance at medium and large character sizes and fixed pitch to be superior for character sizes approaching the acuity limit. The data indicate at least two crowding effects at the smallest sizes: one that interferes with individual character identification and one that interferes with word identification. A control experiment using rapid serial visual presentation suggests that it is the greater horizontal compression and consequently reduced eye-movement requirements of variable pitch that are responsible for its superiority at medium and large character sizes.

  6. Vibration suppression of fixed-time jib crane maneuvers

    SciTech Connect

    Parker, G.G.; Petterson, B.; Dohrmann, C.R.; Robinett, R.D.

    1995-02-01

    A jib crane consists of a pendulum-like end line attached to a rotatable jib. Within this general category of cranes there exist devices with multiple degrees of freedom including variable load-line length and variable jib length. These cranes are commonly used for construction and transportation applications. Point-to-point payload maneuvers using jib cranes are performed so as not to excite the spherical pendulum modes of their cable and payload assemblies. Typically, these pendulum modes, although time-varying, exhibit low frequencies. The resulting maneuvers are therefore performed slowly, contributing to high construction and transportation costs. The crane considered here consists of a spherical pendulum attached to a rigid jib. The other end of the jib is attached to a direct drive motor for generating rotational motion. A general approach is presented for determining the open-loop trajectories for the jib rotation for accomplishing fixed-time, point-to-point, residual oscillation free, symmetric maneuvers. These residual oscillation free trajectories purposely excite the pendulum modes in such a way that at the end of the maneuver the oscillatory degrees of freedom are quiescent. Simulation results are presented with experimental verification.

  7. Exterior building details of Building A; east façade: fixed fiveoverfive ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Exterior building details of Building A; east façade: fixed five-over-five wood windows with five-light hoppers with concrete sills; westerly view - San Quentin State Prison, Building 22, Point San Quentin, San Quentin, Marin County, CA

  8. Completion Rates and Accuracy of Performance Under Fixed and Variable Token Exchange Periods.

    ERIC Educational Resources Information Center

    McLaughlin, T. F.; Malaby, J. E.

    This research investigated the effects of employing fixed, variable, and extended token exchange periods for back-ups on the completion and accuracy of daily assignments for a total fifth and sixth-grade class. The results indicated that, in general, a higher percentage of assignments was completed when the number of days between point exchanges…

  9. Determinants of Human Fixed-Interval Performance Following Varied Exposure to Reinforcement Schedules

    ERIC Educational Resources Information Center

    Torgrud, Laine J.; Holborn, Stephen W.; Zak, Robert D.

    2006-01-01

    Undergraduates given accurate instructions pressed keys for token points under either a variety of reinforcement schedules (variety training) or under a single schedule. Response rates on a fixed-interval (FI) test schedule then were assessed. Experiment 1 compared variety training inclusive of FI-optimal rates (functional) to training excluding…

  10. Route Optimization for Offloading Congested Meter Fixes

    NASA Technical Reports Server (NTRS)

    Xue, Min; Zelinski, Shannon

    2016-01-01

    The Optimized Route Capability (ORC) concept proposed by the FAA facilitates traffic managers to identify and resolve arrival flight delays caused by bottlenecks formed at arrival meter fixes when there exists imbalance between arrival fixes and runways. ORC makes use of the prediction capability of existing automation tools, monitors the traffic delays based on these predictions, and searches the best reroutes upstream of the meter fixes based on the predictions and estimated arrival schedules when delays are over a predefined threshold. Initial implementation and evaluation of the ORC concept considered only reroutes available at the time arrival congestion was first predicted. This work extends previous work by introducing an additional dimension in reroute options such that ORC can find the best time to reroute and overcome the 'firstcome- first-reroute' phenomenon. To deal with the enlarged reroute solution space, a genetic algorithm was developed to solve this problem. Experiments were conducted using the same traffic scenario used in previous work, when an arrival rush was created for one of the four arrival meter fixes at George Bush Intercontinental Houston Airport. Results showed the new approach further improved delay savings. The suggested route changes from the new approach were on average 30 minutes later than those using other approaches, and fewer numbers of reroutes were required. Fewer numbers of reroutes reduce operational complexity and later reroutes help decision makers deal with uncertain situations.

  11. Stress tolerant crops from nitrogen fixing trees

    SciTech Connect

    Becker, R.; Saunders, R.M.

    1983-01-01

    Notes are given on the nutritional quality and uses of: pods of Geoffroea decorticans, a species tolerant of saline and limed soils and saline water; seeds of Olneya tesota which nodulates readily and fixes nitrogen and photosynthesizes at low water potential; and pods of Prosopis chilensis and P. tamarugo which tolerate long periods without rain. 3 references.

  12. Fixing Advising: A Model for Faculty Advising

    ERIC Educational Resources Information Center

    Crocker, Robert M.; Kahla, Marlene; Allen, Charlotte

    2014-01-01

    This paper addresses mandates to fix the advising process with a focus on faculty advising systems. Measures of student success and satisfaction, administrative issues, and faculty concerns are among the many factors discussed. Regression analysis is used to explore long-voiced faculty complaints that students do not follow advice. A case study is…

  13. Why to Treat Subjects as Fixed Effects

    ERIC Educational Resources Information Center

    Adelman, James S.; Estes, Zachary

    2015-01-01

    Adelman, Marquis, Sabatos-DeVito, and Estes (2013) collected word naming latencies from 4 participants who read 2,820 words 50 times each. Their recommendation and practice was that R2 targets set for models should take into account subject idiosyncrasies as replicable patterns, equivalent to a subjects-as-fixed-effects assumption. In light of an…

  14. Force dynamics in fixed-ratio schedules.

    PubMed

    Pinkston, Jonathan W; McBee, Lindsey N

    2014-03-01

    Fixed-ratio schedules are widely used in behavioral research. Although fixed-ratio schedules often conjure up relationships to work and effort, little is known about effort-related measures in these schedules. Early research had shown that force and effort of operant behavior vary systematically during the execution of ratio schedules, and the goal of the present study was to revisit early research on force dynamics in fixed-ratio schedules. Four rats earned sucrose by pressing an isometric force transducer. Presses produced sucrose after ten or twenty responses. In general, the force of responses increased then decreased systematically across the ratio. The possibility that decreases in force during ratio execution was due to a trade-off with the differential reinforcement of short inter-response times (IRT) was investigated in an additional condition where sucrose was made available according to a tandem fixed-ratio 19 inter-response (IRT)> t schedule. The tandem IRT requirement did not eliminate decreasing trends in force across the ratio; unexpectedly, the tandem requirement did eliminate increases in force early in the ratio, which may reflect sequence-level organization operating in the control of force dynamics. PMID:24315798

  15. Fixed drug eruption related to fluconazole.

    PubMed

    Lai, Olivia; Hsu, Sylvia

    2016-01-01

    Fixed drug eruption (FDE) is a type of cutaneous drug reaction that occurs at the same sites upon re-exposure to specific medications. Herein we discuss the case of a 23-year-old man with a FDE to fluconazole. PMID:27617471

  16. The microanalysis of fixed-interval responding

    PubMed Central

    Gentry, G. David; Weiss, Bernard; Laties, Victor G.

    1983-01-01

    The fixed-interval schedule of reinforcement is one of the more widely studied schedules in the experimental analysis of behavior and is also a common baseline for behavior pharmacology. Despite many intensive studies, the controlling variables and the pattern of behavior engendered are not well understood. The present study examined the microstructure and superstructure of the behavior engendered by a fixed-interval 5- and a fixed-interval 15-minute schedule of food reinforcement in the pigeon. Analysis of performance typical of fixed-interval responding indicated that the scalloped pattern does not result from smooth acceleration in responding, but, rather, from renewed pausing early in the interval. Individual interresponse-time (IRT) analyses provided no evidence of acceleration. There was a strong indication of alternation in shorter-longer IRTs, but these shorter-longer IRTs did not occur at random, reflecting instead a sequential dependency in successive IRTs. Furthermore, early in the interval there was a high relative frequency of short IRTs. Such a pattern of early pauses and short IRTs does not suggest behavior typical of reinforced responding as exemplified by the pattern found near the end of the interval. Thus, behavior from clearly scalloped performance can be classified into three states: postreinforcement pause, interim behavior, and terminal behavior. PMID:16812324

  17. Fixed Drug Eruption Due to Ornidazole

    PubMed Central

    Gupta, Ramji

    2014-01-01

    A 56-year-old male developed an ulcer on his glans penis and mucosae of upper and lower lips 3 days after taking ofloxacin, cephalexin, and ornidazole. Clinically, a provisional diagnosis of fixed drug eruption was made. The causative drug was confirmed by an oral provocation test which triggered a reactivation of all lesions only with ornidazole. PMID:25484435

  18. Microanalysis of fixed-interval responding

    SciTech Connect

    Gentry, G.D.; Weiss, B.; Laties, V.G.

    1983-03-01

    The fixed-interval schedule of reinforcement is one of the more widely studied schedules in the experimental analysis of behavior and is also a common baseline for behavior pharmacology. Despite many intensive studies, the controlling variables and the pattern of behavior engendered are not well understood. The present study examined the microstructure and superstructure of the behavior engendered by a fixed-interval 5- and a fixed-interval 15-minute schedule of food reinforcement in the pigeon. Analysis of performance typical of fixed-interval responding indicated that the scalloped pattern does not result from smooth acceleration in responding, but, rather, from renewed pausing early in the interval. Individual interresponse-time (IRT) analyses provided no evidence of acceleration. There was a strong indication of alternation is shorter-longer IRTs, but these shorter-longer IRTs did not occur at random, reflecting instead a sequential dependency in successive IRTs. Furthermore, early in the interval there was a high relative frequency of short IRTs. Such a pattern of early pauses and short IRTs does not suggest behavior typical of reinforced responding as exemplified by the pattern found near the end of the interval. Thus, behavior from clearly scalloped performance can be classified into three states: postreinforcement pause, interim behavior, and terminal behavior. 31 references, 11 figures, 4 tables.

  19. 29 CFR 1917.118 - Fixed ladders.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... and fastened to one or both of the ladder's side rails or to another structure. (2) Fixed ladder means a ladder, including individual rung ladders, permanently attached to a structure, building or piece..., microwave communications, electrical power and similar towers, poles and structures, including stacks...

  20. 29 CFR 1917.118 - Fixed ladders.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... and fastened to one or both of the ladder's side rails or to another structure. (2) Fixed ladder means a ladder, including individual rung ladders, permanently attached to a structure, building or piece..., microwave communications, electrical power and similar towers, poles and structures, including stacks...

  1. Fixing the Shadows While Moving the Gnomon

    ERIC Educational Resources Information Center

    Gangui, Alejandro

    2015-01-01

    It is a common practice to fix a vertical gnomon and study the moving shadow cast by it. This shows our local solar time and gives us a hint regarding the season in which we perform the observation. The moving shadow can also tell us our latitude with high precision. In this paper we propose to exchange the roles and while keeping the shadows…

  2. Unraveling dual feeding associated molecular complexity of salivary glands in the mosquito Anopheles culicifacies

    PubMed Central

    Sharma, Punita; Sharma, Swati; Mishra, Ashwani Kumar; Thomas, Tina; Das De, Tanwee; Rohilla, Suman Lata; Singh, Namita; Pandey, Kailash C.; Valecha, Neena; Dixit, Rajnikant

    2015-01-01

    ABSTRACT Mosquito salivary glands are well known to facilitate meal acquisition, however the fundamental question on how adult female salivary gland manages molecular responses during sugar versus blood meal uptake remains unanswered. To investigate these responses, we analyzed a total of 58.5 million raw reads generated from two independent RNAseq libraries of the salivary glands collected from 3–4 day-old sugar and blood fed Anopheles culicifacies mosquitoes. Comprehensive functional annotation analysis of 10,931 contigs unraveled that salivary glands may encode diverse nature of proteins in response to distinct physiological feeding status. Digital gene expression analysis and PCR validation indicated that first blood meal significantly alters the molecular architecture of the salivary glands. Comparative microscopic analysis also revealed that first blood meal uptake not only causes an alteration of at least 12–22% of morphological features of the salivary glands but also results in cellular changes e.g. apoptosis, confirming together that adult female salivary glands are specialized organs to manage meal specific responses. Unraveling the underlying mechanism of mosquito salivary gene expression, controlling dual feeding associated responses may provide a new opportunity to control vector borne diseases. PMID:26163527

  3. Unraveling protein-protein interactions in clathrin assemblies via atomic force spectroscopy.

    PubMed

    Jin, Albert J; Lafer, Eileen M; Peng, Jennifer Q; Smith, Paul D; Nossal, Ralph

    2013-03-01

    Atomic force microscopy (AFM), single molecule force spectroscopy (SMFS), and single particle force spectroscopy (SPFS) are used to characterize intermolecular interactions and domain structures of clathrin triskelia and clathrin-coated vesicles (CCVs). The latter are involved in receptor-mediated endocytosis (RME) and other trafficking pathways. Here, we subject individual triskelia, bovine-brain CCVs, and reconstituted clathrin-AP180 coats to AFM-SMFS and AFM-SPFS pulling experiments and apply novel analytics to extract force-extension relations from very large data sets. The spectroscopic fingerprints of these samples differ markedly, providing important new information about the mechanism of CCV uncoating. For individual triskelia, SMFS reveals a series of events associated with heavy chain alpha-helix hairpin unfolding, as well as cooperative unraveling of several hairpin domains. SPFS of clathrin assemblies exposes weaker clathrin-clathrin interactions that are indicative of inter-leg association essential for RME and intracellular trafficking. Clathrin-AP180 coats are energetically easier to unravel than the coats of CCVs, with a non-trivial dependence on force-loading rate.

  4. 46 CFR 184.410 - Electronic position fixing devices.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false Electronic position fixing devices. 184.410 Section 184... Electronic position fixing devices. A vessel on an oceans route must be equipped with an electronic position fixing device, capable of providing accurate fixes for the area in which the vessel operates, to...

  5. 46 CFR 184.410 - Electronic position fixing devices.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false Electronic position fixing devices. 184.410 Section 184... Electronic position fixing devices. A vessel on an oceans route must be equipped with an electronic position fixing device, capable of providing accurate fixes for the area in which the vessel operates, to...

  6. 46 CFR 184.410 - Electronic position fixing devices.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false Electronic position fixing devices. 184.410 Section 184... Electronic position fixing devices. A vessel on an oceans route must be equipped with an electronic position fixing device, capable of providing accurate fixes for the area in which the vessel operates, to...

  7. 46 CFR 184.410 - Electronic position fixing devices.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false Electronic position fixing devices. 184.410 Section 184... Electronic position fixing devices. A vessel on an oceans route must be equipped with an electronic position fixing device, capable of providing accurate fixes for the area in which the vessel operates, to...

  8. 46 CFR 184.410 - Electronic position fixing devices.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Electronic position fixing devices. 184.410 Section 184... Electronic position fixing devices. A vessel on an oceans route must be equipped with an electronic position fixing device, capable of providing accurate fixes for the area in which the vessel operates, to...

  9. 50 CFR 660.219 - Fixed gear identification and marking.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 11 2011-10-01 2011-10-01 false Fixed gear identification and marking... West Coast Groundfish-Limited Entry Fixed Gear Fisheries § 660.219 Fixed gear identification and marking. (a) Gear identification. (1) Limited entry fixed gear (longline, trap or pot) must be marked...

  10. 50 CFR 660.219 - Fixed gear identification and marking.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 13 2012-10-01 2012-10-01 false Fixed gear identification and marking... West Coast Groundfish-Limited Entry Fixed Gear Fisheries § 660.219 Fixed gear identification and marking. (a) Gear identification. (1) Limited entry fixed gear (longline, trap or pot) must be marked...

  11. 40 CFR 63.902 - Standards-Tank fixed roof.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 11 2013-07-01 2013-07-01 false Standards-Tank fixed roof. 63.902...) National Emission Standards for Tanks-Level 1 § 63.902 Standards—Tank fixed roof. (a) This section applies... fixed roof. This section does not apply to a fixed-roof tank that is also equipped with an...

  12. 48 CFR 1852.216-75 - Payment of fixed fee.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Payment of fixed fee. 1852... 1852.216-75 Payment of fixed fee. As prescribed in 1816.307-70(c), insert the following clause: Payment of Fixed Fee (DEC 1988) The fixed fee shall be paid in monthly installments based upon the...

  13. 48 CFR 1852.216-75 - Payment of fixed fee.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false Payment of fixed fee. 1852... 1852.216-75 Payment of fixed fee. As prescribed in 1816.307-70(c), insert the following clause: Payment of Fixed Fee (DEC 1988) The fixed fee shall be paid in monthly installments based upon the...

  14. 48 CFR 16.403 - Fixed-price incentive contracts.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Fixed-price incentive... CONTRACTING METHODS AND CONTRACT TYPES TYPES OF CONTRACTS Incentive Contracts 16.403 Fixed-price incentive contracts. (a) Description. A fixed-price incentive contract is a fixed-price contract that provides...

  15. 48 CFR 52.216-9 - Fixed Fee-Construction.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Fixed Fee-Construction. 52....216-9 Fixed Fee—Construction. As prescribed in 16.307(c), insert the following clause in solicitations and contracts when a cost-plus-fixed-fee construction contract is contemplated: Fixed...

  16. 47 CFR 90.235 - Secondary fixed signaling operations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 5 2011-10-01 2011-10-01 false Secondary fixed signaling operations. 90.235... fixed signaling operations. Fixed operations may, subject to the following conditions, be authorized on... function is repeated consecutively more than five times. (h) Fixed stations authorized pursuant to...

  17. 47 CFR 90.637 - Restrictions on operational fixed stations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Restrictions on operational fixed stations. 90... operational fixed stations. (a) Except for control stations, operational fixed operations will not be... secondary fixed tone signaling and alarm operations authorized in § 90.235 or in paragraph (c) of...

  18. 48 CFR 52.216-9 - Fixed Fee-Construction.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 2 2013-10-01 2013-10-01 false Fixed Fee-Construction. 52....216-9 Fixed Fee—Construction. As prescribed in 16.307(c), insert the following clause in solicitations and contracts when a cost-plus-fixed-fee construction contract is contemplated: Fixed...

  19. 47 CFR 90.235 - Secondary fixed signaling operations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Secondary fixed signaling operations. 90.235... fixed signaling operations. Fixed operations may, subject to the following conditions, be authorized on... function is repeated consecutively more than five times. (h) Fixed stations authorized pursuant to...

  20. 10 CFR 600.29 - Fixed obligation awards.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false Fixed obligation awards. 600.29 Section 600.29 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS FINANCIAL ASSISTANCE RULES General § 600.29 Fixed... assistance instruments on a fixed amount basis. Under a fixed obligation award, funds are issued in...

  1. 40 CFR 63.902 - Standards-Tank fixed roof.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 10 2011-07-01 2011-07-01 false Standards-Tank fixed roof. 63.902...) National Emission Standards for Tanks-Level 1 § 63.902 Standards—Tank fixed roof. (a) This section applies... fixed roof. This section does not apply to a fixed-roof tank that is also equipped with an...

  2. 40 CFR 63.902 - Standards-Tank fixed roof.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 11 2012-07-01 2012-07-01 false Standards-Tank fixed roof. 63.902...) National Emission Standards for Tanks-Level 1 § 63.902 Standards—Tank fixed roof. (a) This section applies... fixed roof. This section does not apply to a fixed-roof tank that is also equipped with an...

  3. 48 CFR 1852.216-78 - Firm fixed price.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Firm fixed price. 1852.216... 1852.216-78 Firm fixed price. As prescribed in 1816.202-70, insert the following clause: Firm Fixed Price (DEC 1988) The total firm fixed price of this contract is $ . (End of clause)...

  4. 10 CFR 600.29 - Fixed obligation awards.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false Fixed obligation awards. 600.29 Section 600.29 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS FINANCIAL ASSISTANCE RULES General § 600.29 Fixed... assistance instruments on a fixed amount basis. Under a fixed obligation award, funds are issued in...

  5. 47 CFR 90.235 - Secondary fixed signaling operations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 5 2014-10-01 2014-10-01 false Secondary fixed signaling operations. 90.235... fixed signaling operations. Fixed operations may, subject to the following conditions, be authorized on... function is repeated consecutively more than five times. (h) Fixed stations authorized pursuant to...

  6. 10 CFR 600.29 - Fixed obligation awards.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Fixed obligation awards. 600.29 Section 600.29 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS FINANCIAL ASSISTANCE RULES General § 600.29 Fixed... assistance instruments on a fixed amount basis. Under a fixed obligation award, funds are issued in...

  7. 48 CFR 1852.216-75 - Payment of fixed fee.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Payment of fixed fee. 1852... 1852.216-75 Payment of fixed fee. As prescribed in 1816.307-70(c), insert the following clause: Payment of Fixed Fee (DEC 1988) The fixed fee shall be paid in monthly installments based upon the...

  8. 48 CFR 1852.216-78 - Firm fixed price.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Firm fixed price. 1852.216... 1852.216-78 Firm fixed price. As prescribed in 1816.202-70, insert the following clause: Firm Fixed Price (DEC 1988) The total firm fixed price of this contract is $ . (End of clause)...

  9. 48 CFR 16.403 - Fixed-price incentive contracts.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Fixed-price incentive... CONTRACTING METHODS AND CONTRACT TYPES TYPES OF CONTRACTS Incentive Contracts 16.403 Fixed-price incentive contracts. (a) Description. A fixed-price incentive contract is a fixed-price contract that provides...

  10. 47 CFR 90.637 - Restrictions on operational fixed stations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 5 2013-10-01 2013-10-01 false Restrictions on operational fixed stations. 90... operational fixed stations. (a) Except for control stations, operational fixed operations will not be... secondary fixed tone signaling and alarm operations authorized in § 90.235 or in paragraph (c) of...

  11. 48 CFR 1852.216-78 - Firm fixed price.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Firm fixed price. 1852.216... 1852.216-78 Firm fixed price. As prescribed in 1816.202-70, insert the following clause: Firm Fixed Price (DEC 1988) The total firm fixed price of this contract is $ . (End of clause)...

  12. 2 CFR 200.45 - Fixed amount awards.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Fixed amount awards. 200.45 Section 200.45... REQUIREMENTS FOR FEDERAL AWARDS Acronyms and Definitions Acronyms § 200.45 Fixed amount awards. Fixed amount... primarily on performance and results. See §§ 200.201 Use of grant agreements (including fixed amount...

  13. 40 CFR 63.902 - Standards-Tank fixed roof.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 10 2010-07-01 2010-07-01 false Standards-Tank fixed roof. 63.902...) National Emission Standards for Tanks-Level 1 § 63.902 Standards—Tank fixed roof. (a) This section applies... fixed roof. This section does not apply to a fixed-roof tank that is also equipped with an...

  14. 47 CFR 90.235 - Secondary fixed signaling operations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 5 2012-10-01 2012-10-01 false Secondary fixed signaling operations. 90.235... fixed signaling operations. Fixed operations may, subject to the following conditions, be authorized on... function is repeated consecutively more than five times. (h) Fixed stations authorized pursuant to...

  15. 47 CFR 90.637 - Restrictions on operational fixed stations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 5 2014-10-01 2014-10-01 false Restrictions on operational fixed stations. 90... operational fixed stations. (a) Except for control stations, operational fixed operations will not be... secondary fixed tone signaling and alarm operations authorized in § 90.235 or in paragraph (c) of...

  16. 48 CFR 16.403 - Fixed-price incentive contracts.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Fixed-price incentive... CONTRACTING METHODS AND CONTRACT TYPES TYPES OF CONTRACTS Incentive Contracts 16.403 Fixed-price incentive contracts. (a) Description. A fixed-price incentive contract is a fixed-price contract that provides...

  17. 48 CFR 16.403 - Fixed-price incentive contracts.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Fixed-price incentive... CONTRACTING METHODS AND CONTRACT TYPES TYPES OF CONTRACTS Incentive Contracts 16.403 Fixed-price incentive contracts. (a) Description. A fixed-price incentive contract is a fixed-price contract that provides...

  18. 47 CFR 90.235 - Secondary fixed signaling operations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 5 2013-10-01 2013-10-01 false Secondary fixed signaling operations. 90.235... fixed signaling operations. Fixed operations may, subject to the following conditions, be authorized on... function is repeated consecutively more than five times. (h) Fixed stations authorized pursuant to...

  19. 47 CFR 90.637 - Restrictions on operational fixed stations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 5 2011-10-01 2011-10-01 false Restrictions on operational fixed stations. 90... operational fixed stations. (a) Except for control stations, operational fixed operations will not be... secondary fixed tone signaling and alarm operations authorized in § 90.235 or in paragraph (c) of...

  20. 40 CFR 63.902 - Standards-Tank fixed roof.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 11 2014-07-01 2014-07-01 false Standards-Tank fixed roof. 63.902...) National Emission Standards for Tanks-Level 1 § 63.902 Standards—Tank fixed roof. (a) This section applies... fixed roof. This section does not apply to a fixed-roof tank that is also equipped with an...

  1. 10 CFR 600.29 - Fixed obligation awards.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Fixed obligation awards. 600.29 Section 600.29 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS FINANCIAL ASSISTANCE RULES General § 600.29 Fixed... assistance instruments on a fixed amount basis. Under a fixed obligation award, funds are issued in...

  2. 48 CFR 1852.216-78 - Firm fixed price.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Firm fixed price. 1852.216... 1852.216-78 Firm fixed price. As prescribed in 1816.202-70, insert the following clause: Firm Fixed Price (DEC 1988) The total firm fixed price of this contract is $ . (End of clause)...

  3. 50 CFR 660.219 - Fixed gear identification and marking.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 50 Wildlife and Fisheries 13 2014-10-01 2014-10-01 false Fixed gear identification and marking... West Coast Groundfish-Limited Entry Fixed Gear Fisheries § 660.219 Fixed gear identification and marking. (a) Gear identification. (1) Limited entry fixed gear (longline, trap or pot) must be marked...

  4. 48 CFR 52.216-9 - Fixed Fee-Construction.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 2 2011-10-01 2011-10-01 false Fixed Fee-Construction. 52....216-9 Fixed Fee—Construction. As prescribed in 16.307(c), insert the following clause in solicitations and contracts when a cost-plus-fixed-fee construction contract is contemplated: Fixed...

  5. 48 CFR 52.216-9 - Fixed Fee-Construction.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 2 2012-10-01 2012-10-01 false Fixed Fee-Construction. 52....216-9 Fixed Fee—Construction. As prescribed in 16.307(c), insert the following clause in solicitations and contracts when a cost-plus-fixed-fee construction contract is contemplated: Fixed...

  6. 48 CFR 52.216-9 - Fixed Fee-Construction.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 2 2014-10-01 2014-10-01 false Fixed Fee-Construction. 52....216-9 Fixed Fee—Construction. As prescribed in 16.307(c), insert the following clause in solicitations and contracts when a cost-plus-fixed-fee construction contract is contemplated: Fixed...

  7. 48 CFR 1852.216-75 - Payment of fixed fee.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Payment of fixed fee. 1852... 1852.216-75 Payment of fixed fee. As prescribed in 1816.307-70(c), insert the following clause: Payment of Fixed Fee (DEC 1988) The fixed fee shall be paid in monthly installments based upon the...

  8. 48 CFR 16.403 - Fixed-price incentive contracts.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Fixed-price incentive... CONTRACTING METHODS AND CONTRACT TYPES TYPES OF CONTRACTS Incentive Contracts 16.403 Fixed-price incentive contracts. (a) Description. A fixed-price incentive contract is a fixed-price contract that provides...

  9. 48 CFR 1852.216-78 - Firm fixed price.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false Firm fixed price. 1852.216... 1852.216-78 Firm fixed price. As prescribed in 1816.202-70, insert the following clause: Firm Fixed Price (DEC 1988) The total firm fixed price of this contract is $ . (End of clause)...

  10. 48 CFR 1852.216-75 - Payment of fixed fee.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Payment of fixed fee. 1852... 1852.216-75 Payment of fixed fee. As prescribed in 1816.307-70(c), insert the following clause: Payment of Fixed Fee (DEC 1988) The fixed fee shall be paid in monthly installments based upon the...

  11. 10 CFR 600.29 - Fixed obligation awards.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Fixed obligation awards. 600.29 Section 600.29 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS FINANCIAL ASSISTANCE RULES General § 600.29 Fixed... assistance instruments on a fixed amount basis. Under a fixed obligation award, funds are issued in...

  12. Procedures for Behavioral Experiments in Head-Fixed Mice

    PubMed Central

    Guo, Zengcai V.; Hires, S. Andrew; Li, Nuo; O'Connor, Daniel H.; Komiyama, Takaki; Ophir, Eran; Huber, Daniel; Bonardi, Claudia; Morandell, Karin; Gutnisky, Diego; Peron, Simon; Xu, Ning-long; Cox, James; Svoboda, Karel

    2014-01-01

    The mouse is an increasingly prominent model for the analysis of mammalian neuronal circuits. Neural circuits ultimately have to be probed during behaviors that engage the circuits. Linking circuit dynamics to behavior requires precise control of sensory stimuli and measurement of body movements. Head-fixation has been used for behavioral research, particularly in non-human primates, to facilitate precise stimulus control, behavioral monitoring and neural recording. However, choice-based, perceptual decision tasks by head-fixed mice have only recently been introduced. Training mice relies on motivating mice using water restriction. Here we describe procedures for head-fixation, water restriction and behavioral training for head-fixed mice, with a focus on active, whisker-based tactile behaviors. In these experiments mice had restricted access to water (typically 1 ml/day). After ten days of water restriction, body weight stabilized at approximately 80% of initial weight. At that point mice were trained to discriminate sensory stimuli using operant conditioning. Head-fixed mice reported stimuli by licking in go/no-go tasks and also using a forced choice paradigm using a dual lickport. In some cases mice learned to discriminate sensory stimuli in a few trials within the first behavioral session. Delay epochs lasting a second or more were used to separate sensation (e.g. tactile exploration) and action (i.e. licking). Mice performed a variety of perceptual decision tasks with high performance for hundreds of trials per behavioral session. Up to four months of continuous water restriction showed no adverse health effects. Behavioral performance correlated with the degree of water restriction, supporting the importance of controlling access to water. These behavioral paradigms can be combined with cellular resolution imaging, random access photostimulation, and whole cell recordings. PMID:24520413

  13. Final Report for "Infrared Fixed Points in Multiflavor Lattice Gauge Theory"

    SciTech Connect

    Meurice, Yannick; Sinclair, Donald K.

    2013-09-27

    The goal of the grant was to apply methods that we have developed with spin and pure gauge models to models with dynamical fermions which are considered as candidates for an alternative to the Higgs mechanism. The work on SU(3) with fundamental quarks and with sextet quarks is described.

  14. Fixed points and limit cycles in the population dynamics of lysogenic viruses and their hosts.

    PubMed

    Wang, Zhenyu; Goldenfeld, Nigel

    2010-07-01

    Starting with stochastic rate equations for the fundamental interactions between microbes and their viruses, we derive a mean-field theory for the population dynamics of microbe-virus systems, including the effects of lysogeny. In the absence of lysogeny, our model is a generalization of that proposed phenomenologically by Weitz and Dushoff. In the presence of lysogeny, we analyze the possible states of the system, identifying a limit cycle, which we interpret physically. To test the robustness of our mean-field calculations to demographic fluctuations, we have compared our results with stochastic simulations using the Gillespie algorithm. Finally, we estimate the range of parameters that delineate the various steady states of our model. PMID:20866659

  15. Fixed points and limit cycles in the population dynamics of lysogenic viruses and their hosts

    NASA Astrophysics Data System (ADS)

    Wang, Zhenyu; Goldenfeld, Nigel

    2010-07-01

    Starting with stochastic rate equations for the fundamental interactions between microbes and their viruses, we derive a mean-field theory for the population dynamics of microbe-virus systems, including the effects of lysogeny. In the absence of lysogeny, our model is a generalization of that proposed phenomenologically by Weitz and Dushoff. In the presence of lysogeny, we analyze the possible states of the system, identifying a limit cycle, which we interpret physically. To test the robustness of our mean-field calculations to demographic fluctuations, we have compared our results with stochastic simulations using the Gillespie algorithm. Finally, we estimate the range of parameters that delineate the various steady states of our model.

  16. On equivalence of generalized multi-valued contractions and Nadler's fixed point theorem

    NASA Astrophysics Data System (ADS)

    Eldred, A. Anthony; Anuradha, J.; Veeramani, P.

    2007-12-01

    We consider two generalizations of Nadler's theorem, one proved by Mizoguchi and Takahashi in response to the Reich conjecture and another theorem proved by Kaneko. We show that due to the additional conditions of these theorems the given multi-valued map reduces to a multi-valued contraction mapE We prove this result by showing that the orbit of the multi-valued map is bounded under the contractive conditions of the two generalizations.

  17. Competition Between Transients in the Rate of Approach to a Fixed Point.

    PubMed

    Day, Judy; Rubin, Jonathan E; Chow, Carson C

    2009-11-20

    The goal of this paper is to provide and apply tools for analyzing a specific aspect of transient dynamics not covered by previous theory. The question we address is whether one component of a perturbed solution to a system of differential equations can overtake the corresponding component of a reference solution as both converge to a stable node at the origin, given that the perturbed solution was initially farther away and that both solutions are nonnegative for all time. We call this phenomenon tolerance, for its relation to a biological effect. We show using geometric arguments that tolerance will exist in generic linear systems with a complete set of eigenvectors and in excitable nonlinear systems. We also define a notion of inhibition that may constrain the regions in phase space where the possibility of tolerance arises in general systems. However, these general existence theorems do not not yield an assessment of tolerance for specific initial conditions. To address that issue, we develop some analytical tools for determining if particular perturbed and reference solution initial conditions will exhibit tolerance.

  18. Absence of the Kosterlitz-Thouless fixed points in the Migdal-Kadanoff recursion formulas

    SciTech Connect

    Ito, K.R.

    1985-06-03

    It is shown that the Migdal approximate-renormalization recursion formulas always bring the initial state into the high-temperature region for the U(1)-invariant models at the critical dimensions. This means that the Migdal recursion formulas fail to exhibit the Kosterlitz-Thouless transitions. This is also the case for the recursion formulas of Kadanoff type. The method developed here is extended to non-Abelian systems by some additional tricks.

  19. Competition Between Transients in the Rate of Approach to a Fixed Point

    NASA Astrophysics Data System (ADS)

    Day, Judy; Rubin, Jonathan E.; Chow, Carson C.

    2009-01-01

    The goal of this paper is to provide and apply tools for analyzing a specific aspect of transient dynamics not covered by previous theory. The question we address is whether one component of a perturbed solution to a system of differential equations can overtake the corresponding component of a reference solution as both converge to a stable node at the origin, given that the perturbed solution was initially farther away and that both solutions are nonnegative for all time. We call this phenomenon tolerance, for its relation to a biological effect. We show using geometric arguments that tolerance will exist in generic linear systems with a complete set of eigenvectors and in excitable nonlinear systems. We also define a notion of inhibition that may constrain the regions in phase space where the possibility of tolerance arises in general systems. However, these general existence theorems do not not yield an assessment of tolerance for specific initial conditions. To address that issue, we develop some analytical tools for determining if particular perturbed and reference solution initial conditions will exhibit tolerance.

  20. Periodic solutions in the Kovalevskaya case of a rigid body in rotation about a fixed point

    NASA Astrophysics Data System (ADS)

    El-Sabaa, F. M. F.

    1992-07-01

    The method of small parameters introduced by Poincare is used to obtain the period solution of the problem of a rigid body in the Kovalevskaya case with k (the Kovalevskaya constant of integration) as a small parameter. The asymptotic solution is obtained in terms of elliptic integrals for the (complete integrable) Kovalevskaya top.

  1. Floating Point Control Library

    2007-08-02

    Floating Point Control is a Library that allows for the manipulation of floating point unit exception masking funtions control exceptions in both the Streaming "Single Instruction, Multiple Data" Extension 2 (SSE2) unit and the floating point unit simultaneously. FPC also provides macros to set floating point rounding and precision control.

  2. SPS antenna pointing control

    NASA Technical Reports Server (NTRS)

    Hung, J. C.

    1980-01-01

    The pointing control of a microwave antenna of the Satellite Power System was investigated emphasizing: (1) the SPS antenna pointing error sensing method; (2) a rigid body pointing control design; and (3) approaches for modeling the flexible body characteristics of the solar collector. Accuracy requirements for the antenna pointing control consist of a mechanical pointing control accuracy of three arc-minutes and an electronic phased array pointing accuracy of three arc-seconds. Results based on the factors considered in current analysis, show that the three arc-minute overall pointing control accuracy can be achieved in practice.

  3. Suppression of fixed pattern noise for infrared image system

    NASA Astrophysics Data System (ADS)

    Park, Changhan; Han, Jungsoo; Bae, Kyung-Hoon

    2008-04-01

    In this paper, we propose suppression of fixed pattern noise (FPN) and compensation of soft defect for improvement of object tracking in cooled staring infrared focal plane array (IRFPA) imaging system. FPN appears an observable image which applies to non-uniformity compensation (NUC) by temperature. Soft defect appears glittering black and white point by characteristics of non-uniformity for IR detector by time. This problem is very important because it happen serious problem for object tracking as well as degradation for image quality. Signal processing architecture in cooled staring IRFPA imaging system consists of three tables: low, normal, high temperature for reference gain and offset values. Proposed method operates two offset tables for each table. This is method which operates six term of temperature on the whole. Proposed method of soft defect compensation consists of three stages: (1) separates sub-image for an image, (2) decides a motion distribution of object between each sub-image, (3) analyzes for statistical characteristic from each stationary fixed pixel. Based on experimental results, the proposed method shows an improved image which suppresses FPN by change of temperature distribution from an observational image in real-time.

  4. [Definition and clinical significance of oscillation parameters (fixed frequency technic)].

    PubMed

    Pleger, E; Vogel, J

    1990-01-01

    Starting from the polyvalent sense of a limitation of the maximum available respiratory flow there is to be pointed to the necessity of the decentralized measurement of resistance. The instrument IfM E1 permits the use of the simple forced oscillation technique for estimations of ROS and the derived values delta ROS and STAV all over the country. The advanced forced oscillation method, based on the fixed frequency technique, contained the option for estimation of the residual volume and especially the phase-angle. The knowledge of psi, Re and phi can make the oscillatory testing of airways resistance more surely. Taking into consideration the dependence of the phase signal on lung volume can state noninvasive different facts about the compliance of the lung-thoracic-diaphragm system.

  5. Voltage controlled core reversal of fixed magnetic skyrmions without a magnetic field

    NASA Astrophysics Data System (ADS)

    Bhattacharya, Dhritiman; Al-Rashid, Md Mamun; Atulasimha, Jayasimha

    2016-08-01

    Using micromagnetic simulations we demonstrate core reversal of a fixed magnetic skyrmion by modulating the perpendicular magnetic anisotropy of a nanomagnet with an electric field. We can switch reversibly between two skyrmion states and two ferromagnetic states, i.e. skyrmion states with the magnetization of the core pointing down/up and periphery pointing up/down, and ferromagnetic states with magnetization pointing up/down, by sequential increase and decrease of the perpendicular magnetic anisotropy. The switching between these states is explained by the fact that the spin texture corresponding to each of these stable states minimizes the sum of the magnetic anisotropy, demagnetization, Dzyaloshinskii-Moriya interaction (DMI) and exchange energies. This could lead to the possibility of energy efficient nanomagnetic memory and logic devices implemented with fixed skyrmions without using a magnetic field and without moving skyrmions with a current.

  6. Voltage controlled core reversal of fixed magnetic skyrmions without a magnetic field.

    PubMed

    Bhattacharya, Dhritiman; Al-Rashid, Md Mamun; Atulasimha, Jayasimha

    2016-01-01

    Using micromagnetic simulations we demonstrate core reversal of a fixed magnetic skyrmion by modulating the perpendicular magnetic anisotropy of a nanomagnet with an electric field. We can switch reversibly between two skyrmion states and two ferromagnetic states, i.e. skyrmion states with the magnetization of the core pointing down/up and periphery pointing up/down, and ferromagnetic states with magnetization pointing up/down, by sequential increase and decrease of the perpendicular magnetic anisotropy. The switching between these states is explained by the fact that the spin texture corresponding to each of these stable states minimizes the sum of the magnetic anisotropy, demagnetization, Dzyaloshinskii-Moriya interaction (DMI) and exchange energies. This could lead to the possibility of energy efficient nanomagnetic memory and logic devices implemented with fixed skyrmions without using a magnetic field and without moving skyrmions with a current. PMID:27506159

  7. Voltage controlled core reversal of fixed magnetic skyrmions without a magnetic field

    PubMed Central

    Bhattacharya, Dhritiman; Al-Rashid, Md Mamun; Atulasimha, Jayasimha

    2016-01-01

    Using micromagnetic simulations we demonstrate core reversal of a fixed magnetic skyrmion by modulating the perpendicular magnetic anisotropy of a nanomagnet with an electric field. We can switch reversibly between two skyrmion states and two ferromagnetic states, i.e. skyrmion states with the magnetization of the core pointing down/up and periphery pointing up/down, and ferromagnetic states with magnetization pointing up/down, by sequential increase and decrease of the perpendicular magnetic anisotropy. The switching between these states is explained by the fact that the spin texture corresponding to each of these stable states minimizes the sum of the magnetic anisotropy, demagnetization, Dzyaloshinskii-Moriya interaction (DMI) and exchange energies. This could lead to the possibility of energy efficient nanomagnetic memory and logic devices implemented with fixed skyrmions without using a magnetic field and without moving skyrmions with a current. PMID:27506159

  8. Choice between delayed reinforcers and fixed-ratio schedules requiring forceful responding.

    PubMed

    Mazur, J E; Kralik, J D

    1990-01-01

    This experiment measured pigeons' choices between delayed reinforcers and fixed-ratio schedules in which a force of approximately 0.48 N was needed to operate the response key. In ratio-delay conditions, subjects chose between a fixed-ratio schedule and an adjusting delay. The delay was increased or decreased several times a session in order to estimate an indifference point--a delay duration at which the two alternatives were chosen about equally often. Each ratio-delay condition was followed by a delay-delay condition in which subjects chose between the adjusting delay and a variable-time schedule, with the components of this schedule selected to match the ratio completion times of the preceding ratio-delay condition. The adjusting delays at the indifference point were longer when the alternative was a fixed-ratio schedule than when it was a matched variable-time schedule, which indicated a preference for the matched variable-time schedules over the fixed-ratio schedules. This preference increased in a nonlinear manner with increasing ratio size. This nonlinearity was inconsistent with a theory that states that indifference points for both time and ratio schedules can be predicted by multiplying the choice response-reinforcer intervals of the two types of schedules by different multiplicative constants. Two other theories, which predict nonlinear increases in preference for the matched variable-time schedules, are discussed.

  9. Many-body localization in one dimension as a dynamical renormalization group fixed poin

    NASA Astrophysics Data System (ADS)

    Vosk, Ronen; Altman, Ehud

    2013-03-01

    We formulate a dynamical real space renormalization group approach to describe the time evolution of a random spin-1/2 chain, or interacting fermions, initialized in a state with fixed particle positions. Within this approach we identify a many-body localized state of the chain as a dynamical infinite randomness fixed point. Near this fixed point our method becomes asymptotically exact, allowing analytic calculation of time dependent quantities. In particular we explain the striking universal features in the growth of the entanglement seen in recent numerical simulations: unbounded logarithmic growth delayed by a time inversely proportional to the interaction strength. Lack of true thermalization in the long time limit is attributed to an infinite set of approximate integrals of motion revealed in the course of the RG flow, which become asymptotically exact conservation laws at the fixed point. Hence we identify the many-body localized state with an emergent generalized Gibbs ensemble. Within the RG framework we show that long range resonances are irrelevant at strong randomness, and formulate a criterion for when they do become relevant and may cause a delocalization transition.

  10. A proper fixed functional for four-dimensional Quantum Einstein Gravity

    NASA Astrophysics Data System (ADS)

    Demmel, Maximilian; Saueressig, Frank; Zanusso, Omar

    2015-08-01

    Realizing a quantum theory for gravity based on Asymptotic Safety hinges on the existence of a non-Gaussian fixed point of the theory's renormalization group flow. In this work, we use the functional renormalization group equation for the effective average action to study the fixed point underlying Quantum Einstein Gravity at the functional level including an infinite number of scale-dependent coupling constants. We formulate a list of guiding principles underlying the construction of a partial differential equation encoding the scale-dependence of f( R)-gravity. We show that this equation admits a unique, globally well-defined fixed functional describing the non-Gaussian fixed point at the level of functions of the scalar curvature. This solution is constructed explicitly via a numerical double-shooting method. In the UV, this solution is in good agreement with results from polynomial expansions including a finite number of coupling constants, while it scales proportional to R 2, dressed up with non-analytic terms, in the IR. We demonstrate that its structure is mainly governed by the conformal sector of the flow equation. The relation of our work to previous, partial constructions of similar scaling solutions is discussed.

  11. Fixed-Cell Imaging of Schizosaccharomyces pombe.

    PubMed

    Hagan, Iain M; Bagley, Steven

    2016-01-01

    The acknowledged genetic malleability of fission yeast has been matched by impressive cytology to drive major advances in our understanding of basic molecular cell biological processes. In many of the more recent studies, traditional approaches of fixation followed by processing to accommodate classical staining procedures have been superseded by live-cell imaging approaches that monitor the distribution of fusion proteins between a molecule of interest and a fluorescent protein. Although such live-cell imaging is uniquely informative for many questions, fixed-cell imaging remains the better option for others and is an important-sometimes critical-complement to the analysis of fluorescent fusion proteins by live-cell imaging. Here, we discuss the merits of fixed- and live-cell imaging as well as specific issues for fluorescence microscopy imaging of fission yeast. PMID:27371603

  12. Fixed-rate layered multicast congestion control

    NASA Astrophysics Data System (ADS)

    Bing, Zhang; Bing, Yuan; Zengji, Liu

    2006-10-01

    A new fixed-rate layered multicast congestion control algorithm called FLMCC is proposed. The sender of a multicast session transmits data packets at a fixed rate on each layer, while receivers each obtain different throughput by cumulatively subscribing to deferent number of layers based on their expected rates. In order to provide TCP-friendliness and estimate the expected rate accurately, a window-based mechanism implemented at receivers is presented. To achieve this, each receiver maintains a congestion window, adjusts it based on the GAIMD algorithm, and from the congestion window an expected rate is calculated. To measure RTT, a new method is presented which combines an accurate measurement with a rough estimation. A feedback suppression based on a random timer mechanism is given to avoid feedback implosion in the accurate measurement. The protocol is simple in its implementation. Simulations indicate that FLMCC shows good TCP-friendliness, responsiveness as well as intra-protocol fairness, and provides high link utilization.

  13. Earth stations for fixed and mobile services

    NASA Astrophysics Data System (ADS)

    Charyk, J. V.; Metzger, S.

    1984-07-01

    Communication service provided with the aid of commercial satellites began 18 years ago with the launch of Early Bird (Inselsat I). The present investigation is concerned with the evolution of the earth stations used in the Intelsat system, taking into account the technical, political, and operational factors which have influenced the design of the stations. The success of the Intelsat system led to the use of communication satellites for domestic, maritime, and direct broadcast use. More than 2000 commercial ships communicate via satellite, and by the end of the 1980s, there should be missions of home receivers for direct broadcast satellite television reception. Fixed international service stations are discussed, taking into account overall considerations, antennas, high power amplifiers, low noise amplifiers, multiplex systems, and small earth stations. Attention is also given to fixed domestic service stations, direct broadcast stations, and maritime service.

  14. Fixed flexion deformity and total knee arthroplasty.

    PubMed

    Su, E P

    2012-11-01

    Fixed flexion deformities are common in osteoarthritic knees that are indicated for total knee arthroplasty. The lack of full extension at the knee results in a greater force of quadriceps contracture and energy expenditure. It also results in slower walking velocity and abnormal gait mechanics, overloading the contralateral limb. Residual flexion contractures after TKA have been associated with poorer functional scores and outcomes. Although some flexion contractures may resolve with time after surgery, a substantial percentage will become permanent. Therefore, it is essential to correct fixed flexion deformities at the time of TKA, and be vigilant in the post-operative course to maintain the correction. Surgical techniques to address pre-operative flexion contractures include: adequate bone resection, ligament releases, removal of posterior osteophytes, and posterior capsular releases. Post-operatively, extension can be maintained with focused physiotherapy, a specially modified continuous passive motion machine, a contralateral heel lift, and splinting.

  15. A complete and explicit solution to the three-dimensional problem of two fixed centres

    NASA Astrophysics Data System (ADS)

    Biscani, Francesco; Izzo, Dario

    2016-02-01

    We present for the first time an explicit, complete and closed-form solution to the three-dimensional problem of two fixed centres, based on Weierstrass elliptic and related functions. With respect to previous treatments of the problem, our solution is exact, valid for all initial conditions and physical parameters of the system (including unbounded orbits and repulsive forces), and expressed via a unique set of formulae. Various properties of the three-dimensional problem of two fixed centres are investigated and analysed, with a particular emphasis on quasi-periodic and periodic orbits, regions of motion and equilibrium points.

  16. When water does not boil at the boiling point.

    PubMed

    Chang, Hasok

    2007-03-01

    Every schoolchild learns that, under standard pressure, pure water always boils at 100 degrees C. Except that it does not. By the late 18th century, pioneering scientists had already discovered great variations in the boiling temperature of water under fixed pressure. So, why have most of us been taught that the boiling point of water is constant? And, if it is not constant, how can it be used as a 'fixed point' for the calibration of thermometers? History of science has the answers.

  17. Integrating fixed and removable provisional restorations.

    PubMed

    Curtis, S R

    1993-10-01

    When both fixed and removable components are required, provisional restorations can be difficult. This article describes a technique where provisional restoration "shells" are made with a plastic stent of the diagnostic wax-up on lightly prepared teeth of a diagnostic cast. An acrylic removable partial denture is then waxed to the shells. The shells are relined intraorally after tooth preparation with the partial denture in place.

  18. Coating removal systems - Mobile or fixed?

    NASA Astrophysics Data System (ADS)

    Mangold, Vernon L., Jr.

    1992-04-01

    Various coating removal technologies are discussed from the viewpoint of the process and delivery, with emphasis placed on the mobile Large Aircraft Robot Paint Stripping (LARPS) concept. LARPS is a combined and integrated package of a delivery system and the process media, representing the alternative to the fixed-frame or gantry robot style delivery systems. The paper describes details of the LARPS system design and performance, and presents design diagrams of LARPS.

  19. Fixed drug eruptions with intraoral presentation

    PubMed Central

    Srivastava, Rahul; Bihari, Manorama; Bhuvan, Jyoti; Saad, Ahmed

    2015-01-01

    Fixed-drug eruption (FDE) is an unusual and rare adverse drug reaction. This type of reaction is actually a delayed type of hypersensitivity reaction that occurs as lesions recurring at the same skin site due to repeated intake of an offending drug. Here is a case report of a 58-year-old male patient who developed intraoral FDEs after ingestion of the first dose of ornidazole. PMID:26097341

  20. Unraveling the Motivational Effects and Challenges of Web-Based Collaborative Inquiry Learning across Different Groups of Learners

    ERIC Educational Resources Information Center

    Raes, Annelies; Schellens, Tammy

    2015-01-01

    This study deals with the implementation of a web-based collaborative inquiry (WISE) project in secondary science education and unravels the contribution and challenges of this learning approach to foster students' motivation to learn science, and its relation with student and class-level characteristics. An empirical mixed methods study in 13…

  1. Fixed-combination and emerging glaucoma therapies.

    PubMed

    Woodward, David F; Chen, June

    2007-05-01

    Ocular hypotensive agents are the only approved pharmacotherapy for glaucoma. Despite significant advances during the past two decades, a large proportion of glaucoma patients require more than one drug. The most recent additions to the armamentarium of antiglaucoma drugs are fixed-combination products for the glaucoma patient who is insufficiently responsive to monotherapy. Fixed-combination products have the combined efficacy of two ocular hypotensive drugs, and the convenience of a two-drug treatment regimen in a single container, which may aid patient adherence to treatment. Available fixed-combination products consist of timolol 0.5% as an invariant with brimonidine 0.2%, dorzolamide 2%, travoprost 0.004%, latanoprost 0.005% or bimatoprost 0.03%. Research on more advanced antiglaucoma medications continues. Promising new directions appear to be the Rho-kinase inhibitors, microtubule-disrupting agents, serotonergics and cannabimimetics. Efforts continue to improve existing antiglaucoma drugs in an attempt to design second-generation cholinomimetics, adrenergics, prostaglandins and prostamides. PMID:17604504

  2. Zirconia in fixed prosthesis. A literature review

    PubMed Central

    Román-Rodríguez, Juan L.; Ferreiroa, Alberto; Solá-Ruíz, María F.; Fons-Font, Antonio

    2014-01-01

    Statement of problem: Evidence is limited on the efficacy of zirconia-based fixed dental prostheses. Objective: To carry out a literature review of the behavior of zirconium oxide dental restorations. Material and Methods: This literature review searched the Pubmed, Scopus, Medline and Cochrane Library databases using key search words “zirconium oxide,” “zirconia,” “non-metal restorations,” “ceramic oxides,” “veneering ceramic,” “zirconia-based fixed dental prostheses”. Both in vivo and in vitro studies into zirconia-based prosthodontic restoration behavior were included. Results: Clinical studies have revealed a high rate of fracture for porcelain-veneered zirconia-based restorations that varies between 6% and 15% over a 3- to 5-year period, while for ceramo-metallic restorations the fracture rate ranges between 4 and 10% over ten years. These results provoke uncertainty as to the long-term prognosis for this material in the oral medium. The cause of veneering porcelain fractures is unknown but hypothetically they could be associated with bond failure between the veneer material and the zirconia sub-structure. Key words:Veneering ceramic, zirconia-based ceramic restoration, crown, zirconia, tooth-supported fixed prosthesis. PMID:24596638

  3. RSRM nozzle fixed housing cooldown test

    NASA Technical Reports Server (NTRS)

    Bolieau, D. J.

    1989-01-01

    Flight 5 aft segments with nozzles were exposed to -17 F temperatures while awaiting shipment to KSC in February, 1989. No records were found which show that any previous nozzles were exposed to air temperatures as low as those seen by the Flight 5 nozzles. Thermal analysis shows that the temperature of the fixed housing, and forward and aft exit cone components dropped as low as -10 F. Structural analysis of the nozzles at these low temperatures show the forward and aft exit cone adhesive bonds to have a positive margin of safety, based on a 2.0 safety factor. These analyses show the normal and shear stresses in the fixed housing bond as low values. However, the hoop and meridinal stresses were predicted to be in the 4000 psi range; the failure stress allowable of EA913NA adhesive at -7 F. If the bonds did break in directions perpendicular to the surfaces, called bond crazing, no normal bond strength would be lost. Testing was conducted in two phases, showing that no degradation to the adhesive bonds occurred while the Flight 5 nozzles were subjected to subzero temperatures. The results of these tests are documented. Phase 1 testing cooled a full-scale RSRM insulated fixed housing to -13 F, with extensive bondline inspections. Phase 2 testing cooled the witness panel adhesive tensile buttions to -13 F, with failure strengths recorded before, during, and after the cooldown.

  4. Improvements in the realization of the ITS-90 over the temperature range from the melting point of gallium to the freezing point of silver at NIM

    SciTech Connect

    Sun, J.; Zhang, J. T.; Ping, Q.

    2013-09-11

    The temperature primary standard over the range from the melting point of gallium to the freezing point of silver in National institute of Metrology (NIM), China, was established in the early 1990s. The performance of all of fixed-point furnaces degraded and needs to be updated due to many years of use. Nowadays, the satisfactory fixed point materials can be available with the development of the modern purification techniques. NIM plans to use a group of three cells for each defining fixed point temperature. In this way the eventual drift of individual cells can be evidenced by periodic intercomparison and this will increase the reliability in disseminating the ITS-90 in China. This article describes the recent improvements in realization of ITS-90 over temperature range from the melting point of gallium to the freezing point of silver at NIM. Taking advantages of the technological advances in the design and manufacture of furnaces, the new three-zone furnaces and the open-type fixed points were developed from the freezing point of indium to the freezing point of silver, and a furnace with the three-zone semiconductor cooling was designed to automatically realize the melting point of gallium. The reproducibility of the new melting point of gallium and the new open-type freezing points of In, Sn, Zn. Al and Ag is improved, especially the freezing points of Al and Ag with the reproducibility of 0.2mK and 0.5mK respectively. The expanded uncertainty in the realization of these defining fixed point temperatures is 0.34mK, 0.44mK, 0.54mK, 0.60mK, 1.30mK and 1.88mK respectively.

  5. Unraveling the storage mechanism in organic carbonyl electrodes for sodium-ion batteries

    PubMed Central

    Wu, Xiaoyan; Jin, Shifeng; Zhang, Zhizhen; Jiang, Liwei; Mu, Linqin; Hu, Yong-Sheng; Li, Hong; Chen, Xiaolong; Armand, Michel; Chen, Liquan; Huang, Xuejie

    2015-01-01

    Organic carbonyl compounds represent a promising class of electrode materials for secondary batteries; however, the storage mechanism still remains unclear. We take Na2C6H2O4 as an example to unravel the mechanism. It consists of alternating Na-O octahedral inorganic layer and π-stacked benzene organic layer in spatial separation, delivering a high reversible capacity and first coulombic efficiency. The experiment and calculation results reveal that the Na-O inorganic layer provides both Na+ ion transport pathway and storage site, whereas the benzene organic layer provides electron transport pathway and redox center. Our contribution provides a brand-new insight in understanding the storage mechanism in inorganic-organic layered host and opens up a new exciting direction for designing new materials for secondary batteries. PMID:26601260

  6. Unraveling chaotic attractors by complex networks and measurements of stock market complexity.

    PubMed

    Cao, Hongduo; Li, Ying

    2014-03-01

    We present a novel method for measuring the complexity of a time series by unraveling a chaotic attractor modeled on complex networks. The complexity index R, which can potentially be exploited for prediction, has a similar meaning to the Kolmogorov complexity (calculated from the Lempel-Ziv complexity), and is an appropriate measure of a series' complexity. The proposed method is used to research the complexity of the world's major capital markets. None of these markets are completely random, and they have different degrees of complexity, both over the entire length of their time series and at a level of detail. However, developing markets differ significantly from mature markets. Specifically, the complexity of mature stock markets is stronger and more stable over time, whereas developing markets exhibit relatively low and unstable complexity over certain time periods, implying a stronger long-term price memory process.

  7. Unraveling the storage mechanism in organic carbonyl electrodes for sodium-ion batteries.

    PubMed

    Wu, Xiaoyan; Jin, Shifeng; Zhang, Zhizhen; Jiang, Liwei; Mu, Linqin; Hu, Yong-Sheng; Li, Hong; Chen, Xiaolong; Armand, Michel; Chen, Liquan; Huang, Xuejie

    2015-09-01

    Organic carbonyl compounds represent a promising class of electrode materials for secondary batteries; however, the storage mechanism still remains unclear. We take Na2C6H2O4 as an example to unravel the mechanism. It consists of alternating Na-O octahedral inorganic layer and π-stacked benzene organic layer in spatial separation, delivering a high reversible capacity and first coulombic efficiency. The experiment and calculation results reveal that the Na-O inorganic layer provides both Na(+) ion transport pathway and storage site, whereas the benzene organic layer provides electron transport pathway and redox center. Our contribution provides a brand-new insight in understanding the storage mechanism in inorganic-organic layered host and opens up a new exciting direction for designing new materials for secondary batteries.

  8. Unraveling Markov Processes in Movement Patterns of Indicator Species in Response to Chemical Stressors

    NASA Astrophysics Data System (ADS)

    Nguyen, Tuyen Van; Liu, Yuedan; Jung, Il-Hyo; Chon, Tae-Soo; Lee, Sang-Hee

    Revealing biological responses of organisms in responding to environmental stressors is the critical issue in contemporary ecological sciences. Markov processes in behavioral data were unraveled by utilizing the hidden Markov model (HMM). Individual organisms of daphnia (Daphnia magna) and zebrafish (Danio rerio) were exposed to diazinon at low concentrations. The transition probability matrix (TPM) and the emission probability matrix (EPM) were accordingly estimated by training with the HMM and were verified before and after the treatments with 10-6 tolerance in 103 iterations. Structured property in behavioral changes was accordingly revealed to characterize dynamic processes in movement patterns. Parameters and sequences produced through the HMM training could be a suitable means of monitoring toxic chemicals in environment.

  9. Unraveling the complexity of mitochondrial complex I assembly: A dynamic process.

    PubMed

    Sánchez-Caballero, Laura; Guerrero-Castillo, Sergio; Nijtmans, Leo

    2016-07-01

    Mammalian complex I is composed of 44 different subunits and its assembly requires at least 13 specific assembly factors. Proper function of the mitochondrial respiratory chain enzyme is of crucial importance for cell survival due to its major participation in energy production and cell signaling. Complex I assembly depends on the coordination of several crucial processes that need to be tightly interconnected and orchestrated by a number of assembly factors. The understanding of complex I assembly evolved from simple sequential concept to the more sophisticated modular assembly model describing a convoluted process. According to this model, the different modules assemble independently and associate afterwards with each other to form the final enzyme. In this review, we aim to unravel the complexity of complex I assembly and provide the latest insights in this fundamental and fascinating process. This article is part of a Special Issue entitled Respiratory complex I, edited by Volker Zickermann and Ulrich Brandt.

  10. Unraveling the Mechanism of Nanoscale Mechanical Reinforcement in Glassy Polymer Nanocomposites

    DOE PAGES

    Cheng, Shiwang; Bocharova, Vera; Belianinov, Alex; Xiong, Shaomin; Kisliuk, Alexander; Somnath, Suhas; Holt, Adam P.; Ovchinnikova, Olga S.; Jesse, Stephen; Martin, Halie J.; et al

    2016-05-20

    The mechanical reinforcement of polymer nanocomposites (PNCs) above the glass transition temperature, Tg, has been extensively researched. However, not much is known about the origin of this effect below Tg. In this paper, we unravel the mechanism of PNC reinforcement within the glassy state by directly probing nanoscale mechanical properties with atomic force microscopy and macroscopic properties with Brillouin light scattering. Our results unambiguously show that the "glassy" Young's modulus in the interfacial polymer layer of PNCs is two-times higher than in the bulk polymer, which results in significant reinforcement below Tg. We ascribe this phenomenon to a high stretchingmore » of the chains within the interfacial layer. Since the interfacial chain packing is essentially temperature independent, these findings provide a new insight into the mechanical reinforcement of PNCs also above Tg.« less

  11. Unraveling the effect of polymer dots doping in inverted low bandgap organic solar cells.

    PubMed

    Zhang, Xinyuan; Liu, Chunyu; Li, Jinfeng; He, Yeyuan; Li, Zhiqi; Li, Hao; Shen, Liang; Guo, Wenbin; Ruan, Shengping

    2015-06-28

    In this study, molecular doping with polymer dots was designed to unravel its effect on the photoconductivity in organic solar cells. The photocurrent in organic solar cells exhibited a considerable increase under optimal doping concentration, leading to an ultimate enhancement of power conversion efficiency from 2.30% to 3.64%. This can be attributed primarily to the improvement of the initial boost in charge carriers due to the background carriers induced by the polymer dots and increased tail absorption by the active layer. Based on single carrier device and impedance measurements, polymer dopant can efficiently decrease charge recombination and improve charge carriers mobilities. The obtained achievements pave an approach of molecular doping in affecting the operation of organic solar cells.

  12. Unravelling the nature of non-specific effects of vaccines-A challenge for innate immunologists.

    PubMed

    Jensen, Kristoffer Jarlov; Benn, Christine Stabell; van Crevel, Reinout

    2016-08-01

    Epidemiological observations have shown that vaccines can influence morbidity and mortality more than can be ascribed to target-disease immunity. A growing number of immunological studies have helped identify possible biological mechanisms to explain these so-called nonspecific effects (NSE) of vaccines, including heterologous T-cell reactivity and innate immune memory or 'trained innate immunity', which involves epigenetic reprogramming of innate immune cells. Here, we review the epidemiological evidence for NSE as well as human, animal and in vitro immunological data that could explain these NSE, and discuss priorities for future epidemiologic and immunologic studies to further unravel the biology and optimize the benefits of current and new vaccines. PMID:27354354

  13. Unraveling the complex regulatory relationships between metabolism and signal transduction in cancer

    PubMed Central

    Wynn, Michelle L.; Merajver, Sofia D.; Schnell, Santiago

    2013-01-01

    Cancer cells exhibit an altered metabolic phenotype, known as the Warburg effect, which is characterized by high rates of glucose uptake and glycolysis, even under aerobic conditions. The Warburg effect appears to be an intrinsic component of most cancers and there is evidence linking cancer progression to mutations, translocations, and alternative splicing of genes that directly code for or have downstream effects on key metabolic enzymes. Many of the same signaling pathways are routinely dysregulated in cancer and a number of important oncogenic signaling pathways play important regulatory roles in central carbon metabolism. Unraveling the complex regulatory relationship between cancer metabolism and signaling requires the application of systems biology approaches. Here we discuss computational approaches for modeling protein signal transduction and metabolism as well as how the regulatory relationship between these two important cellular processes can be combined into hybrid models. PMID:22161328

  14. Unravelling a 'miner's myth' that environmental contamination in mining towns is naturally occurring.

    PubMed

    Kristensen, Louise Jane; Taylor, Mark Patrick

    2016-08-01

    Australia has a long history of metal mining and smelting. Extraction and processing have resulted in elevated levels of toxic metals surrounding mining operations, which have adverse health effects, particularly to children. Resource companies, government agencies and employees often construct 'myths' to down play potential exposure risks and responsibility arising from operating emissions. Typical statements include: contaminants are naturally occurring, the wind blows emissions away from residential areas, contaminants are not bioavailable, or the problem is a legacy issue and not related to current operations. Evidence from mining and smelting towns shows that such 'myths' are exactly that. In mining towns, the default and primary defence against contamination is that elevated metals in adjacent urban environments are from the erosion and weathering of the ore bodies over millennia-hence 'naturally occurring'. Not only is this a difficult argument to unravel from an evidence-based perspective, but also it causes confusion and delays remediation work, hindering efforts to reduce harmful exposures to children. An example of this situation is from Broken Hill, New South Wales, home to one of the world's largest lead-zinc-silver ore body, which has been mined continuously for over 130 years. Environmental metal concentration and lead isotopic data from soil samples collected from across Broken Hill are used to establish the nature and timing of lead contamination. We use multiple lines of evidence to unravel a 'miner's myth' by evaluating current soil metal concentrations and lead isotopic compositions, geological data, historical environmental assessments and old photographic evidence to assess the impacts from early smelting along with mining to the surface soils in the city. PMID:26919836

  15. Unravelling a 'miner's myth' that environmental contamination in mining towns is naturally occurring.

    PubMed

    Kristensen, Louise Jane; Taylor, Mark Patrick

    2016-08-01

    Australia has a long history of metal mining and smelting. Extraction and processing have resulted in elevated levels of toxic metals surrounding mining operations, which have adverse health effects, particularly to children. Resource companies, government agencies and employees often construct 'myths' to down play potential exposure risks and responsibility arising from operating emissions. Typical statements include: contaminants are naturally occurring, the wind blows emissions away from residential areas, contaminants are not bioavailable, or the problem is a legacy issue and not related to current operations. Evidence from mining and smelting towns shows that such 'myths' are exactly that. In mining towns, the default and primary defence against contamination is that elevated metals in adjacent urban environments are from the erosion and weathering of the ore bodies over millennia-hence 'naturally occurring'. Not only is this a difficult argument to unravel from an evidence-based perspective, but also it causes confusion and delays remediation work, hindering efforts to reduce harmful exposures to children. An example of this situation is from Broken Hill, New South Wales, home to one of the world's largest lead-zinc-silver ore body, which has been mined continuously for over 130 years. Environmental metal concentration and lead isotopic data from soil samples collected from across Broken Hill are used to establish the nature and timing of lead contamination. We use multiple lines of evidence to unravel a 'miner's myth' by evaluating current soil metal concentrations and lead isotopic compositions, geological data, historical environmental assessments and old photographic evidence to assess the impacts from early smelting along with mining to the surface soils in the city.

  16. Non-Gimbaled Antenna Pointing

    NASA Technical Reports Server (NTRS)

    Vigil, Jeannine S.

    1997-01-01

    The small satellite community has been interested in accessing fixed ground stations for means of space-to-ground transmissions, although a problem arises from the limited global coverage. There is a growing interest for using the Space Network (SN) or Tracking and Data Relay Satellites (TDRS) as the primary support for communications because of the coverage it provides. This thesis will address the potential for satellite access of the Space Network with a non-gimbaled antenna configuration and low-power, coded transmission. The non-gimbaled antenna and the TDRS satellites, TDRS-East, TDRS-West, and TDRS-Zone of Exclusion, were configured in an orbital analysis software package called Satellite Tool Kit to emulate the three-dimensional position of the satellites. The access potential, which is the average number of contacts per day and the average time per contact, were obtained through simulations run over a 30-day period to gain all the possible orientations. The orbital altitude was varied from 600 km through 1200 km with the results being a function of orbital inclination angles varying from 20 deg through 100 deg and pointing half-angles of I0 deg through 40 deg. To compare the validity of the simulations, Jet Propulsion Laboratory granted the use of the TOPEX satellite. The TOPEX satellite was configured to emulate a spin-stabilized antenna with its communications antenna stowed in the zenith-pointing direction. This mimicked the antenna pointing spin-stabilized satellite in the simulations. To make valid comparisons, the TOPEX orbital parameters were entered into Satellite Tool Kit and simulated over five test times provided by Jet Propulsion Laboratory.

  17. Reciprocating and fixed probe measurements of density and temperature in the DIII-D divertor

    NASA Astrophysics Data System (ADS)

    Watkins, J. G.; Moyer, R. A.; Cuthbertson, J. W.; Buchenauer, D. A.; Carlstrom, T. N.; Hill, D. N.; Ulrickson, M.

    1997-02-01

    This paper describes divertor density and temperature measurements using both a new reciprocating Langmuir probe (XPT-RCP) which plunges vertically above the divertor floor up to the X-point height and swept, single, Langmuir probes fixed horizontally across the divertor floor. These types of measurements are important for testing models of the SOL and divertor which then are used to determine engineering design criteria for plasma facing components in reactor size tokamaks. The 6 mm diameter fixed single probes (19 domed and 2 flat at radially equivalent locations) are incorporated into the lower divertor floor at 19 radial locations and swept at 250 Hz. These probes are critical for determining plasma detachment from the floor during operation with high density, highly radiating divertors. By sweeping the divertor strike point across the fixed probes, different regions of the target plate incident flux profile can be sampled and a high resolution spatial profile can be obtained from each probe tip as the strike point moves past. The X-point reciprocating probe (XPT-RCP) provides ne and Te profiles with high spatial (2 mm) and temporal (0.5 ms) resolution from the target plate to the X-point along a single vertical chord at the same radial location as a fixed probe tip at a different azimuthal location. The probe ne and Te are compared to the divertor Thomson scattering (DTS) ne and Te (eight vertical points at 20 Hz, RThomson = RX- point- rcp). Recent observations have also shown divertor densities from 3 × 10 19to 4 × 10 20m-3 near the target plate with the highest densities observed with D 2 gas puffing. Electron temperature is typically of the order of 15-25 eV at the target rising to about 70 eV near the X-point. Lower temperature, higher density plasmas are observed along the inner leg. Generally good agreement among the XPT-RCP, the fixed floor probes, and the DTS is observed. Differences between these diagnostic measurements will also be discussed with

  18. Point by Point: Adding up Motivation

    ERIC Educational Resources Information Center

    Marchionda, Denise

    2010-01-01

    Students often view their course grades as a mysterious equation of teacher-given grades, teacher-given grace, and some other ethereal components based on luck. However, giving students the power to earn points based on numerous daily/weekly assignments and attendance makes the grading process objective and personal, freeing the instructor to…

  19. 76 FR 65118 - Drawbridge Operation Regulation; Bear Creek, Sparrows Point, MD

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-20

    ... SECURITY Coast Guard 33 CFR Part 117 RIN 1625-AA09 Drawbridge Operation Regulation; Bear Creek, Sparrows... Avenue) highway toll drawbridge across Bear Creek, mile 1.5, Sparrows Point, MD was replaced with a fixed... Bear Creek, mile 1.5 was removed and replaced with a fixed bridge in 1998. Prior to 1998, a...

  20. Point specificity in acupuncture

    PubMed Central

    2012-01-01

    The existence of point specificity in acupuncture is controversial, because many acupuncture studies using this principle to select control points have found that sham acupoints have similar effects to those of verum acupoints. Furthermore, the results of pain-related studies based on visual analogue scales have not supported the concept of point specificity. In contrast, hemodynamic, functional magnetic resonance imaging and neurophysiological studies evaluating the responses to stimulation of multiple points on the body surface have shown that point-specific actions are present. This review article focuses on clinical and laboratory studies supporting the existence of point specificity in acupuncture and also addresses studies that do not support this concept. Further research is needed to elucidate the point-specific actions of acupuncture. PMID:22373514

  1. Metabolic syndrome in fixed-shift workers

    PubMed Central

    Canuto, Raquel; Pattussi, Marcos Pascoal; Macagnan, Jamile Block Araldi; Henn, Ruth Liane; Olinto, Maria Teresa Anselmo

    2015-01-01

    OBJECTIVE To analyze if metabolic syndrome and its altered components are associated with demographic, socioeconomic and behavioral factors in fixed-shift workers. METHODS A cross-sectional study was conducted on a sample of 902 shift workers of both sexes in a poultry processing plant in Southern Brazil in 2010. The diagnosis of metabolic syndrome was determined according to the recommendations from Harmonizing the Metabolic Syndrome. Its frequency was evaluated according to the demographic (sex, skin color, age and marital status), socioeconomic (educational level, income and work shift), and behavioral characteristics (smoking, alcohol intake, leisure time physical activity, number of meals and sleep duration) of the sample. The multivariate analysis followed a theoretical framework for identifying metabolic syndrome in fixed-shift workers. RESULTS The prevalence of metabolic syndrome in the sample was 9.3% (95%CI 7.4;11.2). The most frequently altered component was waist circumference (PR 48.4%; 95%CI 45.5;51.2), followed by high-density lipoprotein. Work shift was not associated with metabolic syndrome and its altered components. After adjustment, the prevalence of metabolic syndrome was positively associated with women (PR 2.16; 95%CI 1.28;3.64), workers aged over 40 years (PR 3.90; 95%CI 1.78;8.93) and those who reported sleeping five hours or less per day (PR 1.70; 95%CI 1.09;2.24). On the other hand, metabolic syndrome was inversely associated with educational level and having more than three meals per day (PR 0.43; 95%CI 0.26;0.73). CONCLUSIONS Being female, older and deprived of sleep are probable risk factors for metabolic syndrome, whereas higher educational level and higher number of meals per day are protective factors for metabolic syndrome in fixed-shift workers. PMID:26061455

  2. Quorum Sensing in Nitrogen-Fixing Rhizobia

    PubMed Central

    González, Juan E.; Marketon, Melanie M.

    2003-01-01

    Members of the rhizobia are distinguished for their ability to establish a nitrogen-fixing symbiosis with leguminous plants. While many details of this relationship remain a mystery, much effort has gone into elucidating the mechanisms governing bacterium-host recognition and the events leading to symbiosis. Several signal molecules, including plant-produced flavonoids and bacterially produced nodulation factors and exopolysaccharides, are known to function in the molecular conversation between the host and the symbiont. Work by several laboratories has shown that an additional mode of regulation, quorum sensing, intercedes in the signal exchange process and perhaps plays a major role in preparing and coordinating the nitrogen-fixing rhizobia during the establishment of the symbiosis. Rhizobium leguminosarum, for example, carries a multitiered quorum-sensing system that represents one of the most complex regulatory networks identified for this form of gene regulation. This review focuses on the recent stream of information regarding quorum sensing in the nitrogen-fixing rhizobia. Seminal work on the quorum-sensing systems of R. leguminosarum bv. viciae, R. etli, Rhizobium sp. strain NGR234, Sinorhizobium meliloti, and Bradyrhizobium japonicum is presented and discussed. The latest work shows that quorum sensing can be linked to various symbiotic phenomena including nodulation efficiency, symbiosome development, exopolysaccharide production, and nitrogen fixation, all of which are important for the establishment of a successful symbiosis. Many questions remain to be answered, but the knowledge obtained so far provides a firm foundation for future studies on the role of quorum-sensing mediated gene regulation in host-bacterium interactions. PMID:14665677

  3. Impaired Inhibitory Force Feedback in Fixed Dystonia.

    PubMed

    Mugge, Winfred; Schouten, Alfred C; van Hilten, Jacobus J; van der Helm, Frans C T

    2016-04-01

    Complex regional pain syndrome (CRPS) is a multifactorial disorder associated with an aberrant host response to tissue injury. About 25% of CRPS patients suffer poorly understood involuntary sustained muscle contractions associated with dysfunctional reflexes that result in abnormal postures (fixed dystonia). A recent modeling study simulated fixed dystonia (FD) caused by aberrant force feedback. The current study aims to validate this hypothesis by experimentally recording the modulation of reflexive force feedback in patients with FD. CRPS patients with and without FD, patients with FD but without CRPS, as well as healthy controls participated in the experiment. Three task instructions and three perturbation characteristics were used to evoke a wide range of responses to force perturbations. During position tasks ("maintain posture"), healthy subjects as well as patients resisted the perturbations, becoming more stiff than when being relaxed (i.e., the relax task). Healthy subjects and CRPS patients without FD were both more compliant during force tasks ("maintain force") than during relax tasks, meaning they actively gave way to the imposed forces. Remarkably, the patients with FD failed to do so. A neuromuscular model was fitted to the experimental data to separate the distinct contributions of position, velocity and force feedback, as well as co-contraction to the motor behavior. The neuromuscular modeling indicated that inhibitory force feedback is deregulated in patients with FD, for both CRPS and non-CRPS patients. From previously published simulation results and the present experimental study, it is concluded that aberrant force feedback plays a role in fixed dystonia. PMID:25955788

  4. Finally, fixing health care: what's different now?

    PubMed

    Wyden, Ron; Bennett, Bob

    2008-01-01

    Is now the time to fix the U.S. health care system? Those who remember the failed attempts of the past would say no. We see it differently. Our optimism is rooted in new developments that didn't exist the last time Congress addressed health care. These include bipartisan support for our Healthy Americans Act; an ideological truce over the role of government in health care; common ground between business and labor; the realization that states can't go it alone on health care; the plight of employers in a global marketplace; and the need for coverage that is affordable, accessible, and portable.

  5. Fixed drug eruption due to methaqualone.

    PubMed

    Slazinski, L; Knox, D W

    1984-08-01

    We report three cases of fixed drug eruption due to methaqualone. Eruptions from methaqualone have been rarely reported since the drug's introduction in 1963. Our discovery of these three cases during a two-year period suggests that dermatologic reactions from methaqualone may be much more common than has been appreciated. This may be related to the reluctance of the patient to admit to the use or abuse of methaqualone, and physicians' lack of recognition of the widespread abuse of this drug and its possible cutaneous complications.

  6. Fixed Target Beauty Physics Experimental Programs

    SciTech Connect

    Garbincius, P.H.

    1987-11-01

    The current and near term future fixed target physics efforts in observing particles with open beauty are reviewed. This includes a compilation of the non-observation upper limits and the observation of both upsilon and b-states. A short discussion of the theoretical predictions for the hadro-produced beauty pairs is included. The major part of this review is devoted to the techniques and tricks employed, a survey of the current and proposed experiments. A personal summary of the experimental prospects concludes this report. 28 refs., 26 figs.

  7. [Fixed appliances current state of the art].

    PubMed

    Droschl, H; Eskici, A; Bantleon, H P; Muchitsch, A P

    1989-11-01

    Recent advances in fixed appliances are reviewed and discussed. These include cosmetically more appealing brackets (ceramic, lingual); new wires (nickel-titanium and titanium-molybdenum alloys); new biomechanical approaches (accurate computation of forces and torques according to Burstone resulting in the use of new mechanical concepts); experiences in the treatment of transplanted teeth made in the past 15 years; new approaches to the orthodontic finish (implementation of Andrews' "six keys to normal occlusion" with straight wires, accurate positioning of brackets, and gnathological positioners). Cases will be demonstrated.

  8. ESCAPE FROM SD ASSOCIATED WITH FIXED-RATIO REINFORCEMENT.

    PubMed

    THOMPSON, D M

    1964-01-01

    Throughout ascending and descending fixed-ratio (FR) sequences, rats were allowed to terminate the FR stimulus control by pressing a time-out (TO) lever. To minimize chance or accidental responses on this second lever, three presses were required to produce the 30-sec S(Delta) period. As FR performance became more "strained," there was an increased predisposition to escape from the time-in stimulus complex. The generality of this finding was extended by obtaining recoverability (independent of the direction of stimulus change) of the FR-TO function in the descending series. Typically, escapes were produced only during the post-reinforcement pause; however, under a mixed FR FR schedule, their occurrence shifted to a point within the inter-reinforcement interval corresponding to the unreinforced completion of the lower ratio component. It appears that the point where the rat can discriminate the size of the ratio requirement will be the place where TOs are imposed. This inference was supported by a substantial increase in TO frequency accompanying a shift from CRF to extinction on the FR lever. Finally, the escape lever was placed on a progressively increasing FR schedule and later extinguished to demonstrate that the TO condition was in fact reinforcing.

  9. Ash level meter for a fixed-bed coal gasifier

    DOEpatents

    Fasching, George E.

    1984-01-01

    An ash level meter for a fixed-bed coal gasifier is provided which utilizes the known ash level temperature profile to monitor the ash bed level. A bed stirrer which travels up and down through the extent of the bed ash level is modified by installing thermocouples to measure the bed temperature as the stirrer travels through the stirring cycle. The temperature measurement signals are transmitted to an electronic signal process system by an FM/FM telemetry system. The processing system uses the temperature signals together with an analog stirrer position signal, taken from a position transducer disposed to measure the stirrer position to compute the vertical location of the ash zone upper boundary. The circuit determines the fraction of each total stirrer cycle time the stirrer-derived bed temperature is below a selected set point, multiplies this fraction by the average stirrer signal level, multiplies this result by an appropriate constant and adds another constant such that a 1 to 5 volt signal from the processor corresponds to a 0 to 30 inch span of the ash upper boundary level. Three individual counters in the processor store clock counts that are representative of: (1) the time the stirrer temperature is below the set point (500.degree. F.), (2) the time duration of the corresponding stirrer travel cycle, and (3) the corresponding average stirrer vertical position. The inputs to all three counters are disconnected during any period that the stirrer is stopped, eliminating corruption of the measurement by stirrer stoppage.

  10. Mixed quantum/classical theory of rotationally and vibrationally inelastic scattering in space-fixed and body-fixed reference frames

    SciTech Connect

    Semenov, Alexander; Babikov, Dmitri

    2013-11-07

    We formulated the mixed quantum/classical theory for rotationally and vibrationally inelastic scattering process in the diatomic molecule + atom system. Two versions of theory are presented, first in the space-fixed and second in the body-fixed reference frame. First version is easy to derive and the resultant equations of motion are transparent, but the state-to-state transition matrix is complex-valued and dense. Such calculations may be computationally demanding for heavier molecules and/or higher temperatures, when the number of accessible channels becomes large. In contrast, the second version of theory requires some tedious derivations and the final equations of motion are rather complicated (not particularly intuitive). However, the state-to-state transitions are driven by real-valued sparse matrixes of much smaller size. Thus, this formulation is the method of choice from the computational point of view, while the space-fixed formulation can serve as a test of the body-fixed equations of motion, and the code. Rigorous numerical tests were carried out for a model system to ensure that all equations, matrixes, and computer codes in both formulations are correct.

  11. Critical two-dimensional Ising model with free, fixed ferromagnetic, fixed antiferromagnetic, and double antiferromagnetic boundaries.

    PubMed

    Wu, Xintian; Izmailyan, Nickolay

    2015-01-01

    The critical two-dimensional Ising model is studied with four types boundary conditions: free, fixed ferromagnetic, fixed antiferromagnetic, and fixed double antiferromagnetic. Using bond propagation algorithms with surface fields, we obtain the free energy, internal energy, and specific heat numerically on square lattices with a square shape and various combinations of the four types of boundary conditions. The calculations are carried out on the square lattices with size N×N and 30

  12. Thermal conductivity at a disordered quantum critical point

    NASA Astrophysics Data System (ADS)

    Hartnoll, Sean A.; Ramirez, David M.; Santos, Jorge E.

    2016-04-01

    Strongly disordered and strongly interacting quantum critical points are difficult to access with conventional field theoretic methods. They are, however, both experimentally important and theoretically interesting. In particular, they are expected to realize universal incoherent transport. Such disordered quantum critical theories have recently been constructed holographically by deforming a CFT by marginally relevant disorder. In this paper we find additional disordered fixed points via relevant disordered deformations of a holographic CFT. Using recently developed methods in holographic transport, we characterize the thermal conductivity in both sets of theories in 1+1 dimensions. The thermal conductivity is found to tend to a constant at low temperatures in one class of fixed points, and to scale as T 0.3 in the other. Furthermore, in all cases the thermal conductivity exhibits discrete scale invariance, with logarithmic in temperature oscillations superimposed on the low temperature scaling behavior. At no point do we use the replica trick.

  13. FixO3 : Early progress towards Open Ocean observatory Data Management Harmonisation

    NASA Astrophysics Data System (ADS)

    Pagnani, Maureen; Huber, Robert; Lampitt, Richard

    2014-05-01

    . The data management efforts are central to FixO3. Combined with the procedural and technological harmonisation, tackled in separate work packages, the FixO3 network of observatories will efficiently and cost effectively provide a consistent resource of quality controlled accessible oceanographic data The project website www.fixo3.eu is being developed as both a data showcase and single distribution point, and with database driven tools will enable the sharing of information between the observatories in the most smart and cost effective way. The network of knowledge built throughout the project will become a legacy resource that will ensure access to the unique ensemble data sets only achievable at these key observatories.

  14. Treatment of vertebrobasilar insufficiency--associated vertigo with a fixed combination of cinnarizine and dimenhydrinate.

    PubMed

    Otto, Volker; Fischer, Bernhard; Schwarz, Mario; Baumann, Wolfgang; Preibisch-Effenberger, Rudolf

    2008-01-01

    Thirty-seven patients suffering from vertigo associated with vertebrobasilar insufficiency participated in our prospective, single-center, double-blind, comparative study. Patients were randomly allocated to treatment with placebo; betahistine (12 mg betahistine dimesylate, one tablet three times daily); or the fixed combination of 20 mg cinnarizine and 40 mg dimenhydrinate (one tablet three times daily) for 4 weeks. The primary efficacy end point was the decrease of the mean vertigo score (S(M)), which was based on the patients' assessments of 12 individual vertigo symptoms after 4 weeks of treatment. Patients treated with the fixed combination showed significantly greater reductions of S(M) as compared to patients receiving placebo (p < .001) or the reference therapy betahistine (p < .01). The vestibulospinal parameter lateral sway (Unterberger's test) improved to a significantly greater extent in patients taking the fixed combination as compared to those receiving placebo (p < .001). No serious adverse event was reported in any therapy group. The tolerability of the fixed combination was judged as very good or good by 91% (betahistine, 73%; placebo, 82%). In conclusion, the fixed combination proved to be statistically more effective than the common antivertiginous drug betahistine in reducing vertebrobasilar insufficiency-associated vertigo symptoms. PMID:18616088

  15. 49 CFR 587.18 - Dimensions of fixed rigid barrier.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 7 2012-10-01 2012-10-01 false Dimensions of fixed rigid barrier. 587.18 Section... Deformable Barrier § 587.18 Dimensions of fixed rigid barrier. (a) The fixed rigid barrier has a mass of not less than 7 × 104 kg (154,324 lb). (b) The height of the fixed rigid barrier is at least as high as...

  16. 49 CFR 587.18 - Dimensions of fixed rigid barrier.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 7 2014-10-01 2014-10-01 false Dimensions of fixed rigid barrier. 587.18 Section... Deformable Barrier § 587.18 Dimensions of fixed rigid barrier. (a) The fixed rigid barrier has a mass of not less than 7 × 104 kg (154,324 lb). (b) The height of the fixed rigid barrier is at least as high as...

  17. 49 CFR 587.18 - Dimensions of fixed rigid barrier.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 7 2013-10-01 2013-10-01 false Dimensions of fixed rigid barrier. 587.18 Section... Deformable Barrier § 587.18 Dimensions of fixed rigid barrier. (a) The fixed rigid barrier has a mass of not less than 7 × 104 kg (154,324 lb). (b) The height of the fixed rigid barrier is at least as high as...

  18. Experimental Study on Nonlinear Vibrations of Fixed-Fixed Curved Beams

    NASA Astrophysics Data System (ADS)

    Kumar, Ajay; Patel, B. P.

    2016-07-01

    Nonlinear dynamic behavior of fixed-fixed shallow and deep curved beams is studied experimentally using non-contact type of electromagnetic shaker and acceleration measurements. The frequency response obtained from acceleration measurements is found to be in fairly good agreement with the computational response. The travellingwave phenomenon along with participation of higher harmonics and softening nonlinearity are observed. The experimental results on the internal resonance of curved beams due to direct excitation of anti-symmetric mode are reported for the first time. The deep curved beam depicts chaotic response at higher excitation amplitude.

  19. Fixed Drug Eruption due to Achiote Dye.

    PubMed

    Tattersall, Ian; Reddy, Bobby Y

    2016-01-01

    Fixed drug eruption (FDE) is a localized type IV sensitivity reaction to a systemically introduced allergen. It usually occurs as a result of new medication, making identification and avoidance of the trigger medication straightforward; however, in a rare subset of cases no pharmacological source is identified. In such cases, the causative agent is often a food or food additive. In this report we describe a case of a FDE in a 12-year-old girl recently immigrated to the United States from Ecuador who had no medication exposure over the course of her illness. Through an exhaustive patient history and literature review, we were able to hypothesize that her presentation was caused by a dietary change of the natural achiote dye used in the preparation of yellow rice to a locally available commercial dye mix containing tartrazine, or Yellow 5, which has previously been implicated in both systemic hypersensitivity reactions and specifically in FDE. This report adds to the small body of available literature on non-pharmacological fixed hypersensitivity eruptions and illustrates an effective approach to the management of such a presentation when history is not immediately revealing.

  20. Fixed Drug Eruption due to Achiote Dye

    PubMed Central

    Tattersall, Ian; Reddy, Bobby Y.

    2016-01-01

    Fixed drug eruption (FDE) is a localized type IV sensitivity reaction to a systemically introduced allergen. It usually occurs as a result of new medication, making identification and avoidance of the trigger medication straightforward; however, in a rare subset of cases no pharmacological source is identified. In such cases, the causative agent is often a food or food additive. In this report we describe a case of a FDE in a 12-year-old girl recently immigrated to the United States from Ecuador who had no medication exposure over the course of her illness. Through an exhaustive patient history and literature review, we were able to hypothesize that her presentation was caused by a dietary change of the natural achiote dye used in the preparation of yellow rice to a locally available commercial dye mix containing tartrazine, or Yellow 5, which has previously been implicated in both systemic hypersensitivity reactions and specifically in FDE. This report adds to the small body of available literature on non-pharmacological fixed hypersensitivity eruptions and illustrates an effective approach to the management of such a presentation when history is not immediately revealing. PMID:26933409