Effect of different wall injection schemes on the flow-field of hydrogen fuelled strut-based scramjet combustor

NASA Astrophysics Data System (ADS)

Choubey, Gautam; Pandey, K. M.

2018-04-01

The multi-strut injector is one of the most favourable perspectives for the mixing improvement in between the hydrogen and the high-speed air, and its parametric investigation has drawn an increasing attention among the researchers. Hence the flow-field aspects of a particular multi-strut based scramjet combustor have been investigated numerically with the addition of four wall injectors and at the same time, the influence of combination of different strut as well as wall injector scheme on the performance of multi-strut scramjet engine has also been explored. Moreover, the current computational approach has been validated against the experimental data present in the open literature in case of single strut scramjet engine. The attained results reveal that the collaboration of multi-strut along with 2 wall injectors' improves the efficiency of scramjet as compared to other multi-strut + wall injection scheme as this combination achieve higher penetration height which will boost to a wider temperature and robust combustion area adjacent to the wall. Again, the appearance of extra H2 in the separated flow region precisely ahead of the wall injection region is mainly reasonable for the abrupt decrease in the mixing as well combustion efficiency plot in all the multi-strut + wall injection strategy.

Detecting subsurface fluid leaks in real-time using injection and production rates

NASA Astrophysics Data System (ADS)

Singh, Harpreet; Huerta, Nicolas J.

2017-12-01

CO2 injection into geologic formations for either enhanced oil recovery or carbon storage introduces a risk for undesired fluid leakage into overlying groundwater or to the surface. Despite decades of subsurface CO2 production and injection, the technologies and methods for detecting CO2 leaks are still costly and prone to large uncertainties. This is especially true for pressure-based monitoring methods, which require the use of simplified geological and reservoir flow models to simulate the pressure behavior as well as background noise affecting pressure measurements. In this study, we propose a method to detect the time and volume of fluid leakage based on real-time measurements of well injection and production rates. The approach utilizes analogies between fluid flow and capacitance-resistance modeling. Unlike other leak detection methods (e.g. pressure-based), the proposed method does not require geological and reservoir flow models to simulate the behavior that often carry significant sources of uncertainty; therefore, with our approach the leak can be detected with greater certainty. The method can be applied to detect when a leak begins by tracking a departure in fluid production rate from the expected pattern. The method has been tuned to detect the effect of boundary conditions and fluid compressibility on leakage. To highlight the utility of this approach we use our method to detect leaks for two scenarios. The first scenario simulates a fluid leak from the storage formation into an above-zone monitoring interval. The second scenario simulates intra-reservoir migration between two compartments. We illustrate this method to detect fluid leakage in three different reservoirs with varying levels of geological and structural complexity. The proposed leakage detection method has three novelties: i) requires only readily-available data (injection and production rates), ii) accounts for fluid compressibility and boundary effects, and iii) in addition to detecting the time when a leak is activated and the volume of that leakage, this method provides an insight about the leak location, and reservoir connectivity. We are proposing this as a complementary method that can be used with other, more expensive, methods early on in the injection process. This will allow an operator to conduct more expensive surveys less often because the proposed method can show if there are no leaks on a monthly basis that is cheap and fast.

A computational investigation of fuel mixing in a hypersonic scramjet

NASA Technical Reports Server (NTRS)

Fathauer, Brett W.; Rogers, R. C.

1993-01-01

A parabolized, Navier-Stokes code, SHIP3D, is used to numerically investigate the mixing between air injection and hydrogen injection from a swept ramp injector configuration into either a mainstream low-enthalpy flow or a hypervelocity test flow. The mixing comparisons between air and hydrogen injection reveal the importance of matching injectant-to-mainstream mass flow ratios. In flows with the same injectant-to-mainstream dynamic pressure ratio, the mixing definition was altered for the air injection cases. Comparisons of the computed results indicate that the air injection cases overestimate the mixing performance associated with hydrogen injection simulation. A lifting length parameter, to account for the time a fluid particle transverses through the mixing region, is defined and used to establish a connection of injectant mixing in hypervelocity flows, based on nonreactive, low-enthalpy flows.

Probabilistic risk assessment for CO2 storage in geological formations: robust design and support for decision making under uncertainty

NASA Astrophysics Data System (ADS)

Oladyshkin, Sergey; Class, Holger; Helmig, Rainer; Nowak, Wolfgang

2010-05-01

CO2 storage in geological formations is currently being discussed intensively as a technology for mitigating CO2 emissions. However, any large-scale application requires a thorough analysis of the potential risks. Current numerical simulation models are too expensive for probabilistic risk analysis and for stochastic approaches based on brute-force repeated simulation. Even single deterministic simulations may require parallel high-performance computing. The multiphase flow processes involved are too non-linear for quasi-linear error propagation and other simplified stochastic tools. As an alternative approach, we propose a massive stochastic model reduction based on the probabilistic collocation method. The model response is projected onto a orthogonal basis of higher-order polynomials to approximate dependence on uncertain parameters (porosity, permeability etc.) and design parameters (injection rate, depth etc.). This allows for a non-linear propagation of model uncertainty affecting the predicted risk, ensures fast computation and provides a powerful tool for combining design variables and uncertain variables into one approach based on an integrative response surface. Thus, the design task of finding optimal injection regimes explicitly includes uncertainty, which leads to robust designs of the non-linear system that minimize failure probability and provide valuable support for risk-informed management decisions. We validate our proposed stochastic approach by Monte Carlo simulation using a common 3D benchmark problem (Class et al. Computational Geosciences 13, 2009). A reasonable compromise between computational efforts and precision was reached already with second-order polynomials. In our case study, the proposed approach yields a significant computational speedup by a factor of 100 compared to Monte Carlo simulation. We demonstrate that, due to the non-linearity of the flow and transport processes during CO2 injection, including uncertainty in the analysis leads to a systematic and significant shift of predicted leakage rates towards higher values compared with deterministic simulations, affecting both risk estimates and the design of injection scenarios. This implies that, neglecting uncertainty can be a strong simplification for modeling CO2 injection, and the consequences can be stronger than when neglecting several physical phenomena (e.g. phase transition, convective mixing, capillary forces etc.). The authors would like to thank the German Research Foundation (DFG) for financial support of the project within the Cluster of Excellence in Simulation Technology (EXC 310/1) at the University of Stuttgart. Keywords: polynomial chaos; CO2 storage; multiphase flow; porous media; risk assessment; uncertainty; integrative response surfaces

A multisyringe flow injection Winkler-based spectrophotometric analyzer for in-line monitoring of dissolved oxygen in seawater.

PubMed

Horstkotte, Burkhard; Alonso, Juan Carlos; Miró, Manuel; Cerdà, Víctor

2010-01-15

An integrated analyzer based on the multisyringe flow injection analysis approach is proposed for the automated determination of dissolved oxygen in seawater. The entire Winkler method including precipitation of manganese(II) hydroxide, fixation of dissolved oxygen, dissolution of the oxidized manganese hydroxide precipitate, and generation of iodine and tri-iodide ion are in-line effected within the flow network. Spectrophotometric quantification of iodine and tri-iodide at the isosbestic wavelength of 466nm renders enhanced method reliability. The calibration function is linear up to 19mgL(-1) dissolved oxygen and an injection frequency of 17 per hour is achieved. The multisyringe system features a highly satisfying signal stability with repeatabilities of 2.2% RSD that make it suitable for continuous determination of dissolved oxygen in seawater. Compared to the manual starch-end-point titrimetric Winkler method and early reported automated systems, concentrations and consumption of reagents and sample are reduced up to hundredfold. The versatility of the multisyringe assembly was exploited in the implementation of an ancillary automatic batch-wise Winkler titrator using a single syringe of the module for accurate titration of the released iodine/tri-iodide with thiosulfate.

Effect of injection screen slot geometry on hydraulic conductivity tests

NASA Astrophysics Data System (ADS)

Klammler, Harald; Nemer, Bassel; Hatfield, Kirk

2014-04-01

Hydraulic conductivity and its spatial variability are important hydrogeological parameters and are typically determined through injection tests at different scales. For injection test interpretation, shape factors are required to account for injection screen geometry. Shape factors act as proportionality constants between hydraulic conductivity and observed ratios of injection flow rate and injection head at steady-state. Existing results for such shape factors assume either an ideal screen (i.e., ignoring effects of screen slot geometry) or infinite screen length (i.e., ignoring effects of screen extremes). In the present work, we investigate the combined effects of circumferential screen slot geometry and finite screen length on injection shape factors. This is done in terms of a screen entrance resistance by solving a steady-state potential flow mixed type boundary value problem in a homogeneous axi-symmetric flow domain using a semi-analytical solution approach. Results are compared to existing analytical solutions for circumferential and longitudinal slots on infinite screens, which are found to be identical. Based on an existing approximation, an expression is developed for a dimensionless screen entrance resistance of infinite screens, which is a function of the relative slot area only. For anisotropic conditions, e.g., when conductivity is smaller in the vertical direction than in the horizontal, screen entrance losses for circumferential slots increase, while they remain unaffected for longitudinal slots. This work is not concerned with investigating the effects of (possibly turbulent) head losses inside the injection device including the passage through the injection slots prior to entering the porous aquifer.

Evaluating the reliability of the stream tracer approach to characterize stream-subsurface water exchange

USGS Publications Warehouse

Harvey, Judson W.; Wagner, Brian J.; Bencala, Kenneth E.

1996-01-01

Stream water was locally recharged into shallow groundwater flow paths that returned to the stream (hyporheic exchange) in St. Kevin Gulch, a Rocky Mountain stream in Colorado contaminated by acid mine drainage. Two approaches were used to characterize hyporheic exchange: sub-reach-scale measurement of hydraulic heads and hydraulic conductivity to compute streambed fluxes (hydrometric approach) and reachscale modeling of in-stream solute tracer injections to determine characteristic length and timescales of exchange with storage zones (stream tracer approach). Subsurface data were the standard of comparison used to evaluate the reliability of the stream tracer approach to characterize hyporheic exchange. The reach-averaged hyporheic exchange flux (1.5 mL s−1 m−1), determined by hydrometric methods, was largest when stream base flow was low (10 L s−1); hyporheic exchange persisted when base flow was 10-fold higher, decreasing by approximately 30%. Reliability of the stream tracer approach to detect hyporheic exchange was assessed using first-order uncertainty analysis that considered model parameter sensitivity. The stream tracer approach did not reliably characterize hyporheic exchange at high base flow: the model was apparently more sensitive to exchange with surface water storage zones than with the hyporheic zone. At low base flow the stream tracer approach reliably characterized exchange between the stream and gravel streambed (timescale of hours) but was relatively insensitive to slower exchange with deeper alluvium (timescale of tens of hours) that was detected by subsurface measurements. The stream tracer approach was therefore not equally sensitive to all timescales of hyporheic exchange. We conclude that while the stream tracer approach is an efficient means to characterize surface-subsurface exchange, future studies will need to more routinely consider decreasing sensitivities of tracer methods at higher base flow and a potential bias toward characterizing only a fast component of hyporheic exchange. Stream tracer models with multiple rate constants to consider both fast exchange with streambed gravel and slower exchange with deeper alluvium appear to be warranted.

Coupled Hydro-Mechanical Modeling of Fluid Geological Storage

NASA Astrophysics Data System (ADS)

Castelletto, N.; Garipov, T.; Tchelepi, H. A.

2013-12-01

The accurate modeling of the complex coupled physical processes occurring during the injection and the post-injection period is a key factor for assessing the safety and the feasibility of anthropogenic carbon dioxide (CO2) sequestration in subsurface formations. In recent years, it has become widely accepted the importance of the coupling between fluid flow and geomechanical response in constraining the sustainable pressure buildup caused by fluid injection relative to the caprock sealing capacity, induced seismicity effects and ground surface stability [e.g., Rutqvist, 2012; Castelletto et al., 2013]. Here, we present a modeling approach based on a suitable combination of Finite Volumes (FVs) and Finite Elements (FEs) to solve the coupled system of partial differential equations governing the multiphase flow in a deformable porous medium. Specifically, a FV method is used for the flow problem while the FE method is adopted to address the poro-elasto-plasticity equations. The aim of the present work is to compare the performance and the robustness of unconditionally stable sequential-implicit schemes [Kim et al., 2011] and the fully-implicit method in solving the algebraic systems arising from the discretization of the governing equations, for both normally conditioned and severely ill-conditioned problems. The two approaches are tested against well-known analytical solutions and experimented with in a realistic application of CO2 injection in a synthetic aquifer. References: - Castelletto N., G. Gambolati, and P. Teatini (2013), Geological CO2 sequestration in multi-compartment reservoirs: Geomechanical challenges, J. Geophys. Res. Solid Earth, 118, 2417-2428, doi:10.1002/jgrb.50180. - Kim J., H. A. Tchelepi, and R. Juanes (2011), Stability, accuracy and efficiency of sequential methods for coupled flow and geomechanics, SPE J., 16(2), 249-262. - Rutqvist J. (2012), The geomechanics of CO2 storage in deep sedimentary formations, Geotech. Geol. Eng., 30, 525-551.

Automated on-line renewable solid-phase extraction-liquid chromatography exploiting multisyringe flow injection-bead injection lab-on-valve analysis.

PubMed

Quintana, José Benito; Miró, Manuel; Estela, José Manuel; Cerdà, Víctor

2006-04-15

In this paper, the third generation of flow injection analysis, also named the lab-on-valve (LOV) approach, is proposed for the first time as a front end to high-performance liquid chromatography (HPLC) for on-line solid-phase extraction (SPE) sample processing by exploiting the bead injection (BI) concept. The proposed microanalytical system based on discontinuous programmable flow features automated packing (and withdrawal after single use) of a small amount of sorbent (<5 mg) into the microconduits of the flow network and quantitative elution of sorbed species into a narrow band (150 microL of 95% MeOH). The hyphenation of multisyringe flow injection analysis (MSFIA) with BI-LOV prior to HPLC analysis is utilized for on-line postextraction treatment to ensure chemical compatibility between the eluate medium and the initial HPLC gradient conditions. This circumvents the band-broadening effect commonly observed in conventional on-line SPE-based sample processors due to the low eluting strength of the mobile phase. The potential of the novel MSFI-BI-LOV hyphenation for on-line handling of complex environmental and biological samples prior to reversed-phase chromatographic separations was assessed for the expeditious determination of five acidic pharmaceutical residues (viz., ketoprofen, naproxen, bezafibrate, diclofenac, and ibuprofen) and one metabolite (viz., salicylic acid) in surface water, urban wastewater, and urine. To this end, the copolymeric divinylbenzene-co-n-vinylpyrrolidone beads (Oasis HLB) were utilized as renewable sorptive entities in the micromachined unit. The automated analytical method features relative recovery percentages of >88%, limits of detection within the range 0.02-0.67 ng mL(-1), and coefficients of variation <11% for the column renewable mode and gives rise to a drastic reduction in operation costs ( approximately 25-fold) as compared to on-line column switching systems.

Multi-fluid Dynamics for Supersonic Jet-and-Crossflows and Liquid Plug Rupture

NASA Astrophysics Data System (ADS)

Hassan, Ezeldin A.

Multi-fluid dynamics simulations require appropriate numerical treatments based on the main flow characteristics, such as flow speed, turbulence, thermodynamic state, and time and length scales. In this thesis, two distinct problems are investigated: supersonic jet and crossflow interactions; and liquid plug propagation and rupture in an airway. Gaseous non-reactive ethylene jet and air crossflow simulation represents essential physics for fuel injection in SCRAMJET engines. The regime is highly unsteady, involving shocks, turbulent mixing, and large-scale vortical structures. An eddy-viscosity-based multi-scale turbulence model is proposed to resolve turbulent structures consistent with grid resolution and turbulence length scales. Predictions of the time-averaged fuel concentration from the multi-scale model is improved over Reynolds-averaged Navier-Stokes models originally derived from stationary flow. The response to the multi-scale model alone is, however, limited, in cases where the vortical structures are small and scattered thus requiring prohibitively expensive grids in order to resolve the flow field accurately. Statistical information related to turbulent fluctuations is utilized to estimate an effective turbulent Schmidt number, which is shown to be highly varying in space. Accordingly, an adaptive turbulent Schmidt number approach is proposed, by allowing the resolved field to adaptively influence the value of turbulent Schmidt number in the multi-scale turbulence model. The proposed model estimates a time-averaged turbulent Schmidt number adapted to the computed flowfield, instead of the constant value common to the eddy-viscosity-based Navier-Stokes models. This approach is assessed using a grid-refinement study for the normal injection case, and tested with 30 degree injection, showing improved results over the constant turbulent Schmidt model both in mean and variance of fuel concentration predictions. For the incompressible liquid plug propagation and rupture study, numerical simulations are conducted using an Eulerian-Lagrangian approach with a continuous-interface method. A reconstruction scheme is developed to allow topological changes during plug rupture by altering the connectivity information of the interface mesh. Rupture time is shown to be delayed as the initial precursor film thickness increases. During the plug rupture process, a sudden increase of mechanical stresses on the tube wall is recorded, which can cause tissue damage.

A Resonant Pulse Detonation Actuator for High-Speed Boundary Layer Separation Control

NASA Technical Reports Server (NTRS)

Beck, B. T.; Cutler, A. D.; Drummond, J. P.; Jones, S. B.

2004-01-01

A variety of different types of actuators have been previously investigated as flow control devices. Potential applications include the control of boundary layer separation in external flows, as well as jet engine inlet and diffuser flow control. The operating principles for such devices are typically based on either mechanical deflection of control surfaces (which include MEMS flap devices), mass injection (which includes combustion driven jet actuators), or through the use of synthetic jets (diaphragm devices which produce a pulsating jet with no net mass flow). This paper introduces some of the initial flow visualization work related to the development of a relatively new type of combustion-driven jet actuator that has been proposed based on a pulse detonation principle. The device is designed to utilize localized detonation of a premixed fuel (Hydrogen)-air mixture to periodically inject a jet of gas transversely into the primary flow. Initial testing with airflow successfully demonstrated resonant conditions within the range of acoustic frequencies expected for the design. Schlieren visualization of the pulsating air jet structure revealed axially symmetric vortex flow, along with the formation of shocks. Flow visualization of the first successful sustained oscillation condition is also demonstrated for one configuration of the current test section. Future testing will explore in more detail the onset of resonant combustion and the approach to conditions of sustained resonant detonation.

Determination of tannin in green tea infusion by flow-injection analysis based on quenching the fluorescence of 3-aminophthalate.

PubMed

Chen, Richie L C; Lin, Chun-Hsun; Chung, Chien-Yu; Cheng, Tzong-Jih

2005-11-02

A flow-injection analytical system was developed to determine tannin content in green tea infusions. The flow-injection system is based on measuring the quenching effect of tannin on the fluorescence of 3-aminophthalate. Fluorophore was obtained by auto-oxidation of luminol during solution preparation. System performance was satisfactory for routine analysis (sample throughput >20 h(-1); linear dynamic range for tannic acid, 0.005-0.3 mg/mL; linear dynamic range for green tea tannin, 0.02-1.0 mg/mL; CV < 3%). The flow-injection method is immune from interference by coexisting ascorbate in green tea infusion. Analytical results were verified by the ferrous tartrate method, the Japanese official analytical method.

Simultaneous injection-effective mixing analysis of palladium.

PubMed

Teshima, Norio; Noguchi, Daisuke; Joichi, Yasutaka; Lenghor, Narong; Ohno, Noriko; Sakai, Tadao; Motomizu, Shoji

2010-01-01

A novel concept of simultaneous injection-effective mixing analysis (SIEMA) is proposed, and a SIEMA method applied to the spectrophotometric determination of palladium using a water-soluble chromogenic reagent has been demonstrated. The flow configuration of SIEMA is a hybrid format of flow injection analysis (FIA), sequential injection analysis (SIA) and multicommutation in flow-based analysis. Sample and reagent solutions are aspirated into each holding coil through each solenoid valve by a syringe pump, and then the zones are simultaneously dispensed (injected) into a mixing coil by reversed flow toward a detector through a confluence point. This results in effective mixing and rapid detection with low reagent consumption.

Predictions of spray combustion interactions

NASA Technical Reports Server (NTRS)

Shuen, J. S.; Solomon, A. S. P.; Faeth, G. M.

1984-01-01

Mean and fluctuating phase velocities; mean particle mass flux; particle size; and mean gas-phase Reynolds stress, composition and temperature were measured in stationary, turbulent, axisymmetric, and flows which conform to the boundary layer approximations while having well-defined initial and boundary conditions in dilute particle-laden jets, nonevaporating sprays, and evaporating sprays injected into a still air environment. Three models of the processes, typical of current practice, were evaluated. The local homogeneous flow and deterministic separated flow models did not provide very satisfactory predictions over the present data base. In contrast, the stochastic separated flow model generally provided good predictions and appears to be an attractive approach for treating nonlinear interphase transport processes in turbulent flows containing particles (drops).

Preliminary design of an intermittent smoke flow visualization system

NASA Technical Reports Server (NTRS)

Ward, Donald T.; Myatt, James H.

1993-01-01

A prototype intermittent flow visualization system that was designed to study vortex flow field dynamics has been constructed and tested through its ground test phase. It produces discrete pulses of dense white smoke consisting of particles of terephthalic acid by the pulsing action of a fast-acting three-way valve. The trajectories of the smoke pulses can be tracked by a video imaging system without intruding in the flow around in flight. Two methods of pulsing the smoke were examined. The simplest and safest approach is to simply divert the smoke between the two outlet ports on the valve; this approach should be particularly effective if it were desired to inject smoke at two locations during the same test event. The second approach involves closing off one of the outlet ports to momentarily block the flow. The second approach requires careful control of valve dwell times to avoid excessive pressure buildup within the cartridge container. This method also increases the velocity of the smoke injected into the flow. The flow of the smoke has been blocked for periods ranging from 30 to 80 milliseconds, depending on the system volume and the length of time the valve is allowed to remain open between valve closings.

Effect of cavitation in high-pressure direct injection

NASA Astrophysics Data System (ADS)

Aboulhasanzadeh, Bahman; Johnsen, Eric

2015-11-01

As we move toward higher pressures for Gasoline Direct Injection and Diesel Direct Injection, cavitation has become an important issue. To better understand the effect of cavitation on the nozzle flow and primary atomization, we use a high-order accurate Discontinuous Galerkin approach using multi-GPU parallelism to simulate the compressible flow inside and outside the nozzle. Phase change is included using the six-equations model. We investigate the effect of nozzle geometry on cavitation inside the injector and on primary atomization outside the nozzle.

Mathematical Investigation of Fluid Flow, Mass Transfer, and Slag-steel Interfacial Behavior in Gas-stirred Ladles

NASA Astrophysics Data System (ADS)

Cao, Qing; Nastac, Laurentiu

2018-06-01

In this study, the Euler-Euler and Euler-Lagrange modeling approaches were applied to simulate the multiphase flow in the water model and gas-stirred ladle systems. Detailed comparisons of the computational and experimental results were performed to establish which approach is more accurate for predicting the gas-liquid multiphase flow phenomena. It was demonstrated that the Euler-Lagrange approach is more accurate than the Euler-Euler approach. The Euler-Lagrange approach was applied to study the effects of the free surface setup, injected bubble size, gas flow rate, and slag layer thickness on the slag-steel interaction and mass transfer behavior. Detailed discussions on the flat/non-flat free surface assumption were provided. Significant inaccuracies in the prediction of the surface fluid flow characteristics were found when the flat free surface was assumed. The variations in the main controlling parameters (bubble size, gas flow rate, and slag layer thickness) and their potential impact on the multiphase fluid flow and mass transfer characteristics (turbulent intensity, mass transfer rate, slag-steel interfacial area, flow patterns, etc.,) in gas-stirred ladles were quantitatively determined to ensure the proper increase in the ladle refining efficiency. It was revealed that by injecting finer bubbles as well as by properly increasing the gas flow rate and the slag layer thickness, the ladle refining efficiency can be enhanced significantly.

Parametric effect on the mixing of the combination of a hydrogen porthole with an air porthole in transverse gaseous injection flow fields

NASA Astrophysics Data System (ADS)

Li, Lang-quan; Huang, Wei; Yan, Li; Li, Shi-bin

2017-10-01

The dual transverse injection system with a front hydrogen porthole and a rear air porthole arranged in tandem is proposed, and this is a realistic approach for mixing enhancement and penetration improvement of transverse injection in a scramjet combustor. The influence of this dual transverse injection system on mixing characteristics has been evaluated numerically based on grid independency analysis and code validation. The numerical approach employed in the current study has been validated against the available experimental data in the open literature, and the predicted wall static pressure distributions show reasonable agreement with the experimental data for the cases with different jet-to-crossflow pressure ratios. The obtained results predicted by the three-dimensional Reynolds-average Navier - Stokes (RANS) equations coupled with the two equation k-ω shear stress transport (SST) turbulence model show that the air pothole has an great impact on penetration depth and mixing efficiency, and the effect of air jet on flow field varies with different values of the aspect ratio. The air porthole with larger aspect ratio can increase the fuel penetration depth. However, when the aspect ratio is relatively small, the fuel penetration depth decreases, and even smaller than that of the single injection system. At the same time, the air pothole has a highly remarkable improvement on mixing efficiency, especially in the near field. The smaller the aspect ratio of the air porthole is, the higher the mixing efficiency in the near field is. This is due to its larger circulation in the near field. The dual injection system owns more losses of stagnation pressure than the single injection system.

LES of cavitating flow inside a Diesel injector including dynamic needle movement

NASA Astrophysics Data System (ADS)

Örley, F.; Hickel, S.; Schmidt, S. J.; Adams, N. A.

2015-12-01

We perform large-eddy simulations (LES) of the turbulent, cavitating flow inside a 9-hole solenoid common-rail injector including jet injection into gas during a full injection cycle. The liquid fuel, vapor, and gas phases are modelled by a homogeneous mixture approach. The cavitation model is based on a thermodynamic equilibrium assumption. The geometry of the injector is represented on a Cartesian grid by a conservative cut-element immersed boundary method. The strategy allows for the simulation of complex, moving geometries with sub-cell resolution. We evaluate the effects of needle movement on the cavitation characteristics in the needle seat and tip region during opening and closing of the injector. Moreover, we study the effect of cavitation inside the injector nozzles on primary jet break-up.

Phase Field Model of Hydraulic Fracturing in Poroelastic Media: Fracture Propagation, Arrest, and Branching Under Fluid Injection and Extraction

NASA Astrophysics Data System (ADS)

Santillán, David; Juanes, Ruben; Cueto-Felgueroso, Luis

2018-03-01

The simulation of fluid-driven fracture propagation in a porous medium is a major computational challenge, with applications in geosciences and engineering. The two main families of modeling approaches are those models that represent fractures as explicit discontinuities and solve the moving boundary problem and those that represent fractures as thin damaged zones, solving a continuum problem throughout. The latter family includes the so-called phase field models. Continuum approaches to fracture face validation and verification challenges, in particular grid convergence, well posedness, and physical relevance in practical scenarios. Here we propose a new quasi-static phase field formulation. The approach fully couples fluid flow in the fracture with deformation and flow in the porous medium, discretizes flow in the fracture on a lower-dimension manifold, and employs the fluid flux between the fracture and the porous solid as coupling variable. We present a numerical assessment of the model by studying the propagation of a fracture in the quarter five-spot configuration. We study the interplay between injection flow rate and rock properties and elucidate fracture propagation patterns under the leak-off toughness dominated regime as a function of injection rate, initial fracture length, and poromechanical properties. For the considered injection scenario, we show that the final fracture length depends on the injection rate, and three distinct patterns are observed. We also rationalize the system response using dimensional analysis to collapse the model results. Finally, we propose some simplifications that alleviate the computational cost of the simulations without significant loss of accuracy.

Material flow data for numerical simulation of powder injection molding

NASA Astrophysics Data System (ADS)

Duretek, I.; Holzer, C.

2017-01-01

The powder injection molding (PIM) process is a cost efficient and important net-shape manufacturing process that is not completely understood. For the application of simulation programs for the powder injection molding process, apart from suitable physical models, exact material data and in particular knowledge of the flow behavior are essential in order to get precise numerical results. The flow processes of highly filled polymers are complex. Occurring effects are very hard to separate, like shear flow with yield stress, wall slip, elastic effects, etc. Furthermore, the occurrence of phase separation due to the multi-phase composition of compounds is quite probable. In this work, the flow behavior of a 316L stainless steel feedstock for powder injection molding was investigated. Additionally, the influence of pre-shearing on the flow behavior of PIM-feedstocks under practical conditions was examined and evaluated by a special PIM injection molding machine rheometer. In order to have a better understanding of key factors of PIM during the injection step, 3D non-isothermal numerical simulations were conducted with a commercial injection molding simulation software using experimental feedstock properties. The simulation results were compared with the experimental results. The mold filling studies amply illustrate the effect of mold temperature on the filling behavior during the mold filling stage. Moreover, the rheological measurements showed that at low shear rates no zero shear viscosity was observed, but instead the viscosity further increased strongly. This flow behavior could be described with the Cross-WLF approach with Herschel-Bulkley extension very well.

Injectable Solid Peptide Hydrogel as Cell Carrier: Effects of Shear Flow on Hydrogel and Cell Payload

PubMed Central

Yan, Congqi; Mackay, Michael E.; Czymmek, Kirk; Nagarkar, Radhika P.; Schneider, Joel P.; Pochan, Darrin J.

2012-01-01

β-hairpin peptide-based hydrogels are a class of injectable solid hydrogels that can deliver encapsulated cells or molecular therapies to a target site via syringe or catheter injection as a carrier material. These physical hydrogels can shear-thin and consequently flow as a low-viscosity material under a sufficient shear stress but immediately recover back into a solid upon removal of the stress, allowing them to be injected as preformed gel solids. Hydrogel behavior during flow was studied in a cylindrical capillary geometry that mimicked the actual situation of injection through a syringe needle in order to quantify effects of shear-thin injection delivery on hydrogel flow behavior and encapsulated cell payloads. It was observed that all β-hairpin peptide hydrogels investigated displayed a promising flow profile for injectable cell delivery: a central wide plug flow region where gel material and cell payloads experienced little or no shear rate and a narrow shear zone close to the capillary wall where gel and cells were subject to shear deformation. The width of the plug flow region was found to be weakly dependent on hydrogel rigidity and flow rate. Live-dead assays were performed on encapsulated MG63 cells three hours after injection flow and revealed that shear-thin delivery through the capillary had little impact on cell viability and the spatial distribution of encapsulated cell payloads. These observations help us to fundamentally understand how the gels flow during injection through a thin catheter and how they immediately restore mechanically and morphologically relative to pre-flow, static gels. PMID:22390812

Spheromak plasma flow injection into a torus chamber and the HIST plasmas

NASA Astrophysics Data System (ADS)

Hatuzaki, Akinori

2005-10-01

The importance of plasma flow or two-fluid effect is recognized in understanding the relaxed states of high-beta torus plasmas, start-up and current drive by non-coaxial helicity injection, magnetic reconnection and plasma dynamo in fusion, laboratory and space plasmas. As a new approach to create a flowing two-fluid plasma equilibrium, we have tried to inject tangentially the plasma flow with spheromak-type magnetic configurations into a torus vacuum chamber with an external toroidal magnetic field (TF) coil. In the initial experiments, the RFP-like configuration with helical magnetic structures was realized in the torus vessel. The ion flow measurement with Mach probes showed that the ion flow keeps the same direction despite the reversal of the toroidal current and the axial electric field. The ion fluid comes to flow in the opposite direction to the electron fluid by the reversal of TF. This result suggests that not only electron but also ion flow contributes significantly on the reversed toroidal current. In this case, the ratio of ui to the electron flow velocity ue is estimated as ui/ue ˜ 1/2. We also will inject the spheromak flow into the HIST spherical torus plasmas to examine the possibilities to embedding the two-fluid effect in the ST plasmas.

Performance and stability analysis of gas-injection enhanced natural circulation in heavy-liquid-metal-cooled systems

NASA Astrophysics Data System (ADS)

Yoo, Yeon-Jong

The purpose of this study is to investigate the performance and stability of the gas-injection enhanced natural circulation in heavy-liquid-metal-cooled systems. The target system is STAR-LM, which is a 400-MWt-class advanced lead-cooled fast reactor under development by Argonne National Laboratory and Oregon State University. The primary loop of STAR-LM relies on natural circulation to eliminate main circulation pumps for enhancement of passive safety. To significantly increase the natural circulation flow rate for the incorporation of potential future power uprates, the injection of noncondensable gas into the coolant above the core is envisioned ("gas lift pump"). Reliance upon gas-injection enhanced natural circulation raises the concern of flow instability due to the relatively high temperature change in the reactor core and the two-phase flow condition in the riser. For this study, the one-dimensional flow field equations were applied to each flow section and the mixture models of two-phase flow, i.e., both the homogeneous and drift-flux equilibrium models were used in the two-phase region of the riser. For the stability analysis, the linear perturbation technique based on the frequency-domain approach was used by employing the Nyquist stability criterion and a numerical root search method. It has been shown that the thermal power of the STAR-LM natural circulation system could be increased from 400 up to 1152 MW with gas injection under the limiting void fraction of 0.30 and limiting coolant velocity of 2.0 m/s from the steady-state performance analysis. As the result of the linear stability analysis, it has turned out that the STAR-LM natural circulation system would be stable even with gas injection. In addition, through the parametric study, it has been found that the thermal inertia effects of solid structures such as fuel rod and heat exchanger tube should be considered in the stability analysis model. The results of this study will be a part of the optimized stable design of the gas-injection enhanced natural circulation of STAR-LM with substantially improved power level and economical competitiveness. Furthermore, combined with the parametric study, this research could contribute a guideline for the design of other similar heavy-liquid-metal-cooled natural circulation systems with gas injection.

Numerical simulation of water injection into vapor-dominated reservoirs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pruess, K.

1995-01-01

Water injection into vapor-dominated reservoirs is a means of condensate disposal, as well as a reservoir management tool for enhancing energy recovery and reservoir life. We review different approaches to modeling the complex fluid and heat flow processes during injection into vapor-dominated systems. Vapor pressure lowering, grid orientation effects, and physical dispersion of injection plumes from reservoir heterogeneity are important considerations for a realistic modeling of injection effects. An example of detailed three-dimensional modeling of injection experiments at The Geysers is given.

Injection characteristics study of high-pressure direct injector for Compressed Natural Gas (CNG) using experimental and analytical method

NASA Astrophysics Data System (ADS)

Taha, Z.; Rahim, MF Abdul; Mamat, R.

2017-10-01

The injection characteristics of direct injector affect the mixture formation and combustion processes. In addition, the injector is converted from gasoline operation for CNG application. Thus measurement of CNG direct injector mass flow rate was done by independently tested a single injector on a test bench. The first case investigated the effect of CNG injection pressure and the second case evaluate the effect of pulse-width of injection duration. An analytical model was also developed to predict the mass flow rate of the injector. The injector was operated in a choked condition in both the experiments and simulation studies. In case 1, it was shown that mass flow rate through the injector is affected by injection pressure linearly. Based on the tested injection pressure of 20 bar to 60 bar, the resultant mass flow rate are in the range of 0.4 g/s to 1.2 g/s which are met with theoretical flow rate required by the engine. However, in Case 2, it was demonstrated that the average mass flow rate at short injection durations is lower than recorded in Case 1. At injection pressure of 50 bar, the average mass flow rate for Case 2 and Case 1 are 0.7 g/s and 1.1 g/s respectively. Also, the measured mass flow rate at short injection duration showing a fluctuating data in the range of 0.2 g/s - 1.3 g/s without any noticeable trends. The injector model able to predict the trend of the mass flow rate at different injection pressure but unable to track the fluctuating trend at short injection duration.

Dynamic leaching and fractionation of trace elements from environmental solids exploiting a novel circulating-flow platform.

PubMed

Mori, Masanobu; Nakano, Koji; Sasaki, Masaya; Shinozaki, Haruka; Suzuki, Shiho; Okawara, Chitose; Miró, Manuel; Itabashi, Hideyuki

2016-02-01

A dynamic flow-through microcolumn extraction system based on extractant re-circulation is herein proposed as a novel analytical approach for simplification of bioaccessibility tests of trace elements in sediments. On-line metal leaching is undertaken in the format of all injection (AI) analysis, which is a sequel of flow injection analysis, but involving extraction under steady-state conditions. The minimum circulation times and flow rates required to determine the maximum bioaccessible pools of target metals (viz., Cu, Zn, Cd, and Pb) from lake and river sediment samples were estimated using Tessier's sequential extraction scheme and an acid single extraction test. The on-line AIA method was successfully validated by mass balance studies of CRM and real sediment samples. Tessier's test in on-line AI format demonstrated to be carried out by one third of extraction time (6h against more than 17 h by the conventional method), with better analytical precision (<9.2% against >15% by the conventional method) and significant decrease in blank readouts as compared with the manual batch counterpart. Copyright © 2015 Elsevier B.V. All rights reserved.

Pressure-controlled injection of guar gum stabilized microscale zerovalent iron for groundwater remediation.

PubMed

Luna, M; Gastone, F; Tosco, T; Sethi, R; Velimirovic, M; Gemoets, J; Muyshondt, R; Sapion, H; Klaas, N; Bastiaens, L

2015-10-01

The paper reports a pilot injection test of microsized zerovalent iron (mZVI) dispersed in a guar gum shear thinning solution. The test was performed in the framework of the EU research project AQUAREHAB in a site in Belgium contaminated by chlorinated aliphatic hydrocarbons (CAHs). The field application was aimed to overcome those critical aspects which hinder mZVI field injection, mainly due to the colloidal instability of ZVI-based suspensions. The iron slurry properties (iron particles size and concentration, polymeric stabilizer type and concentration, slurry viscosity) were designed in the laboratory based on several tests (reactivity tests towards contaminants, sedimentation tests and rheological measurements). The particles were delivered into the aquifer through an injection well specifically designed for controlled-pressure delivery (approximately 10 bars). The well characteristics and the critical pressure of the aquifer (i.e. the injection pressure above which fracturing occurs) were assessed via two innovative injection step rate tests, one performed with water and the other one with guar gum. Based on laboratory and field preliminary tests, a flow regime at the threshold between permeation and preferential flow was selected for mZVI delivery, as a compromise between the desired homogeneous distribution of the mZVI around the injection point (ensured by permeation flow) and the fast and effective injection of the slurry (guaranteed by high discharge rates and injection pressure, resulting in the generation of preferential flow paths). A monitoring setup was designed and installed for the real-time monitoring of relevant parameters during injection, and for a fast determination of the spatial mZVI distribution after injection via non-invasive magnetic susceptibility measurements. Copyright © 2015 Elsevier B.V. All rights reserved.

Modeling frictional melt injection to constrain coseismic physical conditions

NASA Astrophysics Data System (ADS)

Sawyer, William J.; Resor, Phillip G.

2017-07-01

Pseudotachylyte, a fault rock formed through coseismic frictional melting, provides an important record of coseismic mechanics. In particular, injection veins formed at a high angle to the fault surface have been used to estimate rupture directivity, velocity, pulse length, stress drop, as well as slip weakening distance and wall rock stiffness. These studies have generally treated injection vein formation as a purely elastic process and have assumed that processes of melt generation, transport, and solidification have little influence on the final vein geometry. Using a pressurized crack model, an analytical approximation of injection vein formation based on dike intrusion, we find that the timescales of quenching and flow propagation may be similar for a subset of injection veins compiled from the Asbestos Mountain Fault, USA, Gole Larghe Fault Zone, Italy, and the Fort Foster Brittle Zone, USA under minimum melt temperature conditions. 34% of the veins are found to be flow limited, with a final geometry that may reflect cooling of the vein before it reaches an elastic equilibrium with the wall rock. Formation of these veins is a dynamic process whose behavior is not fully captured by the analytical approach. To assess the applicability of simplifying assumptions of the pressurized crack we employ a time-dependent finite-element model of injection vein formation that couples elastic deformation of the wall rock with the fluid dynamics and heat transfer of the frictional melt. This finite element model reveals that two basic assumptions of the pressurized crack model, self-similar growth and a uniform pressure gradient, are false. The pressurized crack model thus underestimates flow propagation time by 2-3 orders of magnitude. Flow limiting may therefore occur under a wider range of conditions than previously thought. Flow-limited veins may be recognizable in the field where veins have tapered profiles or smaller aspect ratios than expected. The occurrence and shape of injection veins can be coupled with modeling to provide an independent estimate of minimum melt temperature. Finally, the large aspect ratio observed for all three populations of injection veins may be best explained by a large reduction in stiffness associated with coseismic damage, as injection vein growth is likely to far exceed the lifetime of dynamic stresses at any location along a fault.

Assessment of the Partially Resolved Numerical Simulation (PRNS) Approach in the National Combustion Code (NCC) for Turbulent Nonreacting and Reacting Flows

NASA Technical Reports Server (NTRS)

Shih, Tsan-Hsing; Liu, Nan-Suey

2008-01-01

This paper describes an approach which aims at bridging the gap between the traditional Reynolds-averaged Navier-Stokes (RANS) approach and the traditional large eddy simulation (LES) approach. It has the characteristics of the very large eddy simulation (VLES) and we call this approach the partially-resolved numerical simulation (PRNS). Systematic simulations using the National Combustion Code (NCC) have been carried out for fully developed turbulent pipe flows at different Reynolds numbers to evaluate the PRNS approach. Also presented are the sample results of two demonstration cases: nonreacting flow in a single injector flame tube and reacting flow in a Lean Direct Injection (LDI) hydrogen combustor.

An innovative computationally efficient hydromechanical coupling approach for fault reactivation in geological subsurface utilization

NASA Astrophysics Data System (ADS)

Adams, M.; Kempka, T.; Chabab, E.; Ziegler, M.

2018-02-01

Estimating the efficiency and sustainability of geological subsurface utilization, i.e., Carbon Capture and Storage (CCS) requires an integrated risk assessment approach, considering the occurring coupled processes, beside others, the potential reactivation of existing faults. In this context, hydraulic and mechanical parameter uncertainties as well as different injection rates have to be considered and quantified to elaborate reliable environmental impact assessments. Consequently, the required sensitivity analyses consume significant computational time due to the high number of realizations that have to be carried out. Due to the high computational costs of two-way coupled simulations in large-scale 3D multiphase fluid flow systems, these are not applicable for the purpose of uncertainty and risk assessments. Hence, an innovative semi-analytical hydromechanical coupling approach for hydraulic fault reactivation will be introduced. This approach determines the void ratio evolution in representative fault elements using one preliminary base simulation, considering one model geometry and one set of hydromechanical parameters. The void ratio development is then approximated and related to one reference pressure at the base of the fault. The parametrization of the resulting functions is then directly implemented into a multiphase fluid flow simulator to carry out the semi-analytical coupling for the simulation of hydromechanical processes. Hereby, the iterative parameter exchange between the multiphase and mechanical simulators is omitted, since the update of porosity and permeability is controlled by one reference pore pressure at the fault base. The suggested procedure is capable to reduce the computational time required by coupled hydromechanical simulations of a multitude of injection rates by a factor of up to 15.

Double injection/single detection asymmetric flow injection manifold for spectrophotometric determination of ascorbic acid and uric acid: Selection the optimal conditions by MCDM approach based on different criteria weighting methods.

PubMed

Boroumand, Samira; Chamjangali, Mansour Arab; Bagherian, Ghadamali

2017-03-05

A simple and sensitive double injection/single detector flow injection analysis (FIA) method is proposed for the simultaneous kinetic determination of ascorbic acid (AA) and uric acid (UA). This method is based upon the difference between the rates of the AA and UA reactions with Fe 3+ in the presence of 1, 10-phenanthroline (phen). The absorbance of Fe 2+ /1, 10-phenanthroline (Fe-phen) complex obtained as the product was measured spectrophotometrically at 510nm. To reach a good accuracy in the differential kinetic determination via the mathematical manipulations of the transient signals, different criteria were considered in the selection of the optimum conditions. The multi criteria decision making (MCDM) approach was applied for the selection of the optimum conditions. The importance weights of the evaluation criteria were determined using the analytic hierarchy process, entropy method, and compromised weighting (CW). The experimental conditions (alternatives) were ranked by the technique for order preference by similarity to an ideal solution. Under the selected optimum conditions, the obtained analytical signals were linear in the ranges of 0.50-5.00 and 0.50-4.00mgL -1 for AA and UA, respectively. The 3σ detection limits were 0.07mgL -1 for AA and 0.12mgL -1 for UA. The relative standard deviations for four replicate determinations of AA and UA were 2.03% and 3.30% respectively. The method was also applied for the analysis of analytes in the blood serum, Vitamine C tablets, and tap water with satisfactory results. Copyright © 2016. Published by Elsevier B.V.

Double injection/single detection asymmetric flow injection manifold for spectrophotometric determination of ascorbic acid and uric acid: Selection the optimal conditions by MCDM approach based on different criteria weighting methods

NASA Astrophysics Data System (ADS)

Boroumand, Samira; Chamjangali, Mansour Arab; Bagherian, Ghadamali

2017-03-01

A simple and sensitive double injection/single detector flow injection analysis (FIA) method is proposed for the simultaneous kinetic determination of ascorbic acid (AA) and uric acid (UA). This method is based upon the difference between the rates of the AA and UA reactions with Fe3 + in the presence of 1, 10-phenanthroline (phen). The absorbance of Fe2 +/1, 10-phenanthroline (Fe-phen) complex obtained as the product was measured spectrophotometrically at 510 nm. To reach a good accuracy in the differential kinetic determination via the mathematical manipulations of the transient signals, different criteria were considered in the selection of the optimum conditions. The multi criteria decision making (MCDM) approach was applied for the selection of the optimum conditions. The importance weights of the evaluation criteria were determined using the analytic hierarchy process, entropy method, and compromised weighting (CW). The experimental conditions (alternatives) were ranked by the technique for order preference by similarity to an ideal solution. Under the selected optimum conditions, the obtained analytical signals were linear in the ranges of 0.50-5.00 and 0.50-4.00 mg L- 1 for AA and UA, respectively. The 3σ detection limits were 0.07 mg L- 1 for AA and 0.12 mg L- 1 for UA. The relative standard deviations for four replicate determinations of AA and UA were 2.03% and 3.30% respectively. The method was also applied for the analysis of analytes in the blood serum, Vitamine C tablets, and tap water with satisfactory results.

Approach to solution of coupled heat transfer problem on the surface of hypersonic vehicle of arbitrary shape

NASA Astrophysics Data System (ADS)

Bocharov, A. N.; Bityurin, V. A.; Golovin, N. N.; Evstigneev, N. M.; Petrovskiy, V. P.; Ryabkov, O. I.; Teplyakov, I. O.; Shustov, A. A.; Solomonov, Yu S.; Fortov, V. E.

2016-11-01

In this paper, an approach to solve conjugate heat- and mass-transfer problems is considered to be applied to hypersonic vehicle surface of arbitrary shape. The approach under developing should satisfy the following demands. (i) The surface of the body of interest may have arbitrary geometrical shape. (ii) The shape of the body can change during calculation. (iii) The flight characteristics may vary in a wide range, specifically flight altitude, free-stream Mach number, angle-of-attack, etc. (iv) The approach should be realized with using the high-performance-computing (HPC) technologies. The approach is based on coupled solution of 3D unsteady hypersonic flow equations and 3D unsteady heat conductance problem for the thick wall. Iterative process is applied to account for ablation of wall material and, consequently, mass injection from the surface and changes in the surface shape. While iterations, unstructured computational grids both in the flow region and within the wall interior are adapted to the current geometry and flow conditions. The flow computations are done on HPC platform and are most time-consuming part of the whole problem, while heat conductance problem can be solved on many kinds of computers.

Novel approaches to analysis by flow injection gradient titration.

PubMed

Wójtowicz, Marzena; Kozak, Joanna; Kościelniak, Paweł

2007-09-26

Two novel procedures for flow injection gradient titration with the use of a single stock standard solution are proposed. In the multi-point single-line (MP-SL) method the calibration graph is constructed on the basis of a set of standard solutions, which are generated in a standard reservoir and subsequently injected into the titrant. According to the single-point multi-line (SP-ML) procedure the standard solution and a sample are injected into the titrant stream from four loops of different capacities, hence four calibration graphs are able to be constructed and the analytical result is calculated on the basis of a generalized slope of these graphs. Both approaches have been tested on the example of spectrophotometric acid-base titration of hydrochloric and acetic acids with using bromothymol blue and phenolphthalein as indicators, respectively, and sodium hydroxide as a titrant. Under optimized experimental conditions the analytical results of precision less than 1.8 and 2.5% (RSD) and of accuracy less than 3.0 and 5.4% (relative error (RE)) were obtained for MP-SL and SP-ML procedures, respectively, in ranges of 0.0031-0.0631 mol L(-1) for samples of hydrochloric acid and of 0.1680-1.7600 mol L(-1) for samples of acetic acid. The feasibility of both methods was illustrated by applying them to the total acidity determination in vinegar samples with precision lower than 0.5 and 2.9% (RSD) for MP-SL and SP-ML procedures, respectively.

Multiphasic modelling of bone-cement injection into vertebral cancellous bone.

PubMed

Bleiler, Christian; Wagner, Arndt; Stadelmann, Vincent A; Windolf, Markus; Köstler, Harald; Boger, Andreas; Gueorguiev-Rüegg, Boyko; Ehlers, Wolfgang; Röhrle, Oliver

2015-01-01

Percutaneous vertebroplasty represents a current procedure to effectively reinforce osteoporotic bone via the injection of bone cement. This contribution considers a continuum-mechanically based modelling approach and simulation techniques to predict the cement distributions within a vertebra during injection. To do so, experimental investigations, imaging data and image processing techniques are combined and exploited to extract necessary data from high-resolution μCT image data. The multiphasic model is based on the Theory of Porous Media, providing the theoretical basis to describe within one set of coupled equations the interaction of an elastically deformable solid skeleton, of liquid bone cement and the displacement of liquid bone marrow. The simulation results are validated against an experiment, in which bone cement was injected into a human vertebra under realistic conditions. The major advantage of this comprehensive modelling approach is the fact that one can not only predict the complex cement flow within an entire vertebra but is also capable of taking into account solid deformations in a fully coupled manner. The presented work is the first step towards the ultimate and future goal of extending this framework to a clinical tool allowing for pre-operative cement distribution predictions by means of numerical simulations. Copyright © 2015 John Wiley & Sons, Ltd.

Fracture Propagation, Fluid Flow, and Geomechanics of Water-Based Hydraulic Fracturing in Shale Gas Systems and Electromagnetic Geophysical Monitoring of Fluid Migration

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, Jihoon; Um, Evan; Moridis, George

2014-12-01

We investigate fracture propagation induced by hydraulic fracturing with water injection, using numerical simulation. For rigorous, full 3D modeling, we employ a numerical method that can model failure resulting from tensile and shear stresses, dynamic nonlinear permeability, leak-off in all directions, and thermo-poro-mechanical effects with the double porosity approach. Our numerical results indicate that fracture propagation is not the same as propagation of the water front, because fracturing is governed by geomechanics, whereas water saturation is determined by fluid flow. At early times, the water saturation front is almost identical to the fracture tip, suggesting that the fracture is mostlymore » filled with injected water. However, at late times, advance of the water front is retarded compared to fracture propagation, yielding a significant gap between the water front and the fracture top, which is filled with reservoir gas. We also find considerable leak-off of water to the reservoir. The inconsistency between the fracture volume and the volume of injected water cannot properly calculate the fracture length, when it is estimated based on the simple assumption that the fracture is fully saturated with injected water. As an example of flow-geomechanical responses, we identify pressure fluctuation under constant water injection, because hydraulic fracturing is itself a set of many failure processes, in which pressure consistently drops when failure occurs, but fluctuation decreases as the fracture length grows. We also study application of electromagnetic (EM) geophysical methods, because these methods are highly sensitive to changes in porosity and pore-fluid properties due to water injection into gas reservoirs. Employing a 3D finite-element EM geophysical simulator, we evaluate the sensitivity of the crosswell EM method for monitoring fluid movements in shaly reservoirs. For this sensitivity evaluation, reservoir models are generated through the coupled flow-geomechanical simulator and are transformed via a rock-physics model into electrical conductivity models. It is shown that anomalous conductivity distribution in the resulting models is closely related to injected water saturation, but not closely related to newly created unsaturated fractures. Our numerical modeling experiments demonstrate that the crosswell EM method can be highly sensitive to conductivity changes that directly indicate the migration pathways of the injected fluid. Accordingly, the EM method can serve as an effective monitoring tool for distribution of injected fluids (i.e., migration pathways) during hydraulic fracturing operations« less

Simplified Physics Based Models Research Topical Report on Task #2

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mishra, Srikanta; Ganesh, Priya

We present a simplified-physics based approach, where only the most important physical processes are modeled, to develop and validate simplified predictive models of CO2 sequestration in deep saline formation. The system of interest is a single vertical well injecting supercritical CO2 into a 2-D layered reservoir-caprock system with variable layer permeabilities. We use a set of well-designed full-physics compositional simulations to understand key processes and parameters affecting pressure propagation and buoyant plume migration. Based on these simulations, we have developed correlations for dimensionless injectivity as a function of the slope of fractional-flow curve, variance of layer permeability values, and themore » nature of vertical permeability arrangement. The same variables, along with a modified gravity number, can be used to develop a correlation for the total storage efficiency within the CO2 plume footprint. Similar correlations are also developed to predict the average pressure within the injection reservoir, and the pressure buildup within the caprock.« less

Determination of Hypochlorite in Bleaching Products with Flower Extracts to Demonstrate the Principles of Flow Injection Analysis

ERIC Educational Resources Information Center

Ramos, Luiz Antonio; Prieto, Katia Roberta; Carvalheiro, Eder Tadeu Gomes; Carvalheiro, Carla Cristina Schmitt

2005-01-01

The use of crude flower extracts to the principle of analytical chemistry automation, with the flow injection analysis (FIA) procedure developed to determine hypochlorite in household bleaching products was performed. The FIA comprises a group of techniques based on injection of a liquid sample into a moving, nonsegmented carrier stream of a…

Encapsulation of Fluidic Tubing and Microelectrodes in Microfluidic Devices: Integrating Off-Chip Process and Coupling Conventional Capillary Electrophoresis with Electrochemical Detection

PubMed Central

Becirovic, Vedada; Doonan, Steven R.; Martin, R. Scott

2013-01-01

In this paper, an approach to fabricate epoxy or polystyrene microdevices with encapsulated tubing and electrodes is described. Key features of this approach include a fixed alignment between the fluidic tubing and electrodes, the ability to polish the device when desired, and the low dead volume nature of the fluidic interconnects. It is shown that a variety of tubing can be encapsulated with this approach, including fused silica capillary, polyetheretherketone (PEEK), and perfluoroalkoxy (PFA), with the resulting tubing/microchip interface not leading to significant band broadening or plug dilution. The applicability of the devices with embedded tubing is demonstrated by integrating several off-chip analytical methods to the microchip. This includes droplet transfer, droplet desegmentation, and microchip-based flow injection analysis. Off-chip generated droplets can be transferred to the microchip with minimal coalescence, while flow injection studies showed improved peak shape and sensitivity when compared to the use of fluidic interconnects with an appreciable dead volume. Importantly, it is shown that this low dead volume approach can be extended to also enable the integration of conventional capillary electrophoresis (CE) with electrochemical detection. This is accomplished by embedding fused silica capillary along with palladium (for grounding the electrophoresis voltage) and platinum (for detection) electrodes. With this approach, up to 128,000 theoretical plates for dopamine was possible. In all cases, the tubing and electrodes are housed in a rigid base; this results in extremely robust devices that will be of interest to researchers wanting to develop microchips for use by non-experts. PMID:24159363

Encapsulation of Fluidic Tubing and Microelectrodes in Microfluidic Devices: Integrating Off-Chip Process and Coupling Conventional Capillary Electrophoresis with Electrochemical Detection.

PubMed

Becirovic, Vedada; Doonan, Steven R; Martin, R Scott

2013-08-21

In this paper, an approach to fabricate epoxy or polystyrene microdevices with encapsulated tubing and electrodes is described. Key features of this approach include a fixed alignment between the fluidic tubing and electrodes, the ability to polish the device when desired, and the low dead volume nature of the fluidic interconnects. It is shown that a variety of tubing can be encapsulated with this approach, including fused silica capillary, polyetheretherketone (PEEK), and perfluoroalkoxy (PFA), with the resulting tubing/microchip interface not leading to significant band broadening or plug dilution. The applicability of the devices with embedded tubing is demonstrated by integrating several off-chip analytical methods to the microchip. This includes droplet transfer, droplet desegmentation, and microchip-based flow injection analysis. Off-chip generated droplets can be transferred to the microchip with minimal coalescence, while flow injection studies showed improved peak shape and sensitivity when compared to the use of fluidic interconnects with an appreciable dead volume. Importantly, it is shown that this low dead volume approach can be extended to also enable the integration of conventional capillary electrophoresis (CE) with electrochemical detection. This is accomplished by embedding fused silica capillary along with palladium (for grounding the electrophoresis voltage) and platinum (for detection) electrodes. With this approach, up to 128,000 theoretical plates for dopamine was possible. In all cases, the tubing and electrodes are housed in a rigid base; this results in extremely robust devices that will be of interest to researchers wanting to develop microchips for use by non-experts.

Active Flow Separation Control of a Stator Vane Using Surface Injection in a Multistage Compressor Experiment

NASA Technical Reports Server (NTRS)

Culley, Dennis E.; Bright, Michelle M.; Prahst, Patricia S.; Strazisar, Anthony J.

2003-01-01

Micro-flow control actuation embedded in a stator vane was used to successfully control separation and improve near stall performance in a multistage compressor rig at NASA Glenn. Using specially designed stator vanes configured with internal actuation to deliver pulsating air through slots along the suction surface, a research study was performed to identify performance benefits using this microflow control approach. Pressure profiles and unsteady pressure measurements along the blade surface and at the shroud provided a dynamic look at the compressor during microflow air injection. These pressure measurements lead to a tracking algorithm to identify the onset of separation. The testing included steady air injection at various slot locations along the vane. The research also examined the benefit of pulsed injection and actively controlled air injection along the stator vane. Two types of actuation schemes were studied, including an embedded actuator for on-blade control. Successful application of an online detection and flow control scheme will be discussed. Testing showed dramatic performance benefit for flow reattachment and subsequent improvement in diffusion through the use of pulsed controlled injection. The paper will discuss the experimental setup, the blade configurations, and preliminary CFD results which guided the slot location along the blade. The paper will also show the pressure profiles and unsteady pressure measurements used to track flow control enhancement, and will conclude with the tracking algorithm for adjusting the control.

Transverse injection into Mach 2 flow behind a rearward-facing step - A 3-D, compressible flow test case for hypersonic combustor CFD validation

NASA Technical Reports Server (NTRS)

Mcdaniel, James C.; Fletcher, Douglas G.; Hartfield, Roy J.; Hollo, Steven D.

1991-01-01

A spatially-complete data set of the important primitive flow variables is presented for the complex, nonreacting, 3D unit combustor flow field employing transverse injection into a Mach 2 flow behind a rearward-facing step. A unique wind tunnel facility providing the capability for iodine seeding was built specifically for these measurements. Two optical techniques based on laser-induced-iodine fluorescence were developed and utilized for nonintrusive, in situ flow field measurements. LDA provided both mean and fluctuating velocity component measurements. A thermographic phosphor wall temperature measurement technique was developed and employed. Data from the 2D flow over a rearward-facing step and the complex 3D mixing flow with injection are reported.

Effects of injection pressure variation on mixing in a cold supersonic combustor with kerosene fuel

NASA Astrophysics Data System (ADS)

Liu, Wei-Lai; Zhu, Lin; Qi, Yin-Yin; Ge, Jia-Ru; Luo, Feng; Zou, Hao-Ran; Wei, Min; Jen, Tien-Chien

2017-10-01

Spray jet in cold kerosene-fueled supersonic flow has been characterized under different injection pressures to assess the effects of the pressure variation on the mixing between incident shock wave and transverse cavity injection. Based on the real scramjet combustor, a detailed computational fluid dynamics model is developed. The injection pressures are specified as 0.5, 1.0, 2.0, 3.0 and 4.0 MPa, respectively, with the other constant operation parameters (such as the injection diameter, angle and velocity). A three dimensional Couple Level Set & Volume of Fluids approach incorporating an improved Kelvin-Helmholtz & Rayleigh-Taylor model is used to investigate the interaction between kerosene and supersonic air. The numerical simulations primarily concentrate on penetration depth, span expansion area, angle of shock wave and sauter mean diameter distribution of the kerosene droplets with/without evaporation. Validation has been implemented by comparing the calculated against the measured in literature with good qualitative agreement. Results show that the penetration depth, span-wise angle and expansion area of the transverse cavity jet are all increased with the injection pressure. However, when the injection pressure is further increased, the value in either penetration depth or expansion area increases appreciably. This study demonstrates the feasibility and effectiveness of the combination of Couple Level Set & Volume of Fluids approach and an improved Kelvin-Helmholtz & Rayleigh-Taylor model, in turn providing insights into scramjet design improvement.

A volumetric flow sensor for automotive injection systems

NASA Astrophysics Data System (ADS)

Schmid, U.; Krötz, G.; Schmitt-Landsiedel, D.

2008-04-01

For further optimization of the automotive power train of diesel engines, advanced combustion processes require a highly flexible injection system, provided e.g. by the common rail (CR) injection technique. In the past, the feasibility to implement injection nozzle volumetric flow sensors based on the thermo-resistive measurement principle has been demonstrated up to injection pressures of 135 MPa (1350 bar). To evaluate the transient behaviour of the system-integrated flow sensors as well as an injection amount indicator used as a reference method, hydraulic simulations on the system level are performed for a CR injection system. Experimentally determined injection timings were found to be in good agreement with calculated values, especially for the novel sensing element which is directly implemented into the hydraulic system. For the first time pressure oscillations occurring after termination of the injection pulse, predicted theoretically, could be verified directly in the nozzle. In addition, the injected amount of fuel is monitored with the highest resolution ever reported in the literature.

Evaluation of Flow-Injection Tandem Mass Spectrometry for Rapid and High-Throughput Quantitative Determination of B-Vitamins in Nutritional Supplements

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bhandari, Deepak; Van Berkel, Gary J

2012-01-01

The use of flow-injection electrospray ionization tandem mass spectrometry for rapid and high-throughput mass spectral analysis of selected B-vitamins, viz. B1, B2, B3, B5, and B6, in nutritional formulations was demonstrated. A simple and rapid (~5 min) in-tube sample preparation was performed by adding extraction solvent to a powdered sample aliquot followed by agitation, centrifugation, and filtration to recover an extract for analysis. Automated flow injection introduced 1 L of the extracts directly into the mass spectrometer ion source without chromatographic separation. Sample-to-sample analysis time was 60 s representing significant improvement over conventional liquid chromatography approaches which typically require 25-45more » min, and often require more significant sample preparation procedures. Quantitative capabilities of the flow-injection analysis were tested using the method of standard additions and NIST standard reference material (SRM 3280) multivitamin/multielement tablets. The quantity determined for each B-vitamin in SRM 3280 was within the statistical range provided for the respective certified values. The same sample preparation and analysis approach was also applied to two different commercial vitamin supplement tablets and proved to be successful in the quantification of the selected B-vitamins as evidenced by an agreement with the labels values and the results obtained using isotope dilution liquid chromatography/mass spectrometry.« less

Modeling contrast agent flow in cerebral aneurysms: comparison of CFD with medical imaging

NASA Astrophysics Data System (ADS)

Rayz, Vitaliy; Vali, Alireza; Sigovan, Monica; Lawton, Michael; Saloner, David; Boussel, Loic

2016-11-01

PURPOSE: The flow in cerebral aneurysms is routinely assessed with X-ray angiography, an imaging technique based on a contrast agent injection. In addition to requiring a patient's catheterization and radiation exposure, the X-ray angiography may inaccurately estimate the flow residence time, as the injection alters the native blood flow patterns. Numerical modeling of the contrast transport based on MRI imaging, provides a non-invasive alternative for the flow diagnostics. METHODS: The flow in 3 cerebral aneurysms was measured in vivo with 4D PC-MRI, which provides time-resolved, 3D velocity field. The measured velocities were used to simulate a contrast agent transport by solving the advection-diffusion equation. In addition, the flow in the same patient-specific geometries was simulated with CFD and the velocities obtained from the Navier-Stokes solution were used to model the transport of a virtual contrast. RESULTS: Contrast filling and washout patterns obtained in simulations based on MRI-measured velocities were in agreement with those obtained using the Navier-Stokes solution. Some discrepancies were observed in comparison to the X-ray angiography data, as numerical modeling of the contrast transport is based on the native blood flow unaffected by the contrast injection. NIH HL115267.

Planning and Analysis of Fractured Rock Injection Tests in the Cerro Brillador Underground Laboratory, Northern Chile

NASA Astrophysics Data System (ADS)

Fairley, J. P., Jr.; Oyarzún L, R.; Villegas, G.

2015-12-01

Early theories of fluid migration in unsaturated fractured rock hypothesized that matrix suction would dominate flow up to the point of matrix saturation. However, experiments in underground laboratories such as the ESF (Yucca Mountain, NV) have demonstrated that liquid water can migrate significant distances through fractures in an unsaturated porous medium, suggesting limited interaction between fractures and unsaturated matrix blocks and potentially rapid transmission of recharge to the sat- urated zone. Determining the conditions under which this rapid recharge may take place is an important factor in understanding deep percolation processes in arid areas with thick unsaturated zones. As part of an on-going, Fondecyt-funded project (award 11150587) to study mountain block hydrological processes in arid regions, we are plan- ning a series of in-situ fracture flow injection tests in the Cerro Brillador/Mina Escuela, an underground laboratory and teaching facility belonging to the Universidad la Serena, Chile. Planning for the tests is based on an analytical model and curve-matching method, originally developed to evaluate data from injection tests at Yucca Mountain (Fairley, J.P., 2010, WRR 46:W08542), that uses a known rate of liquid injection to a fracture (for example, from a packed-off section of borehole) and the observed rate of seepage discharging from the fracture to estimate effective fracture aperture, matrix sorptivity, fracture/matrix flow partitioning, and the wetted fracture/matrix interac- tion area between the injection and recovery points. We briefly review the analytical approach and its application to test planning and analysis, and describe the proposed tests and their goals.

Object-based inversion of crosswell radar tomography data to monitor vegetable oil injection experiments

USGS Publications Warehouse

Lane, John W.; Day-Lewis, Frederick D.; Versteeg, Roelof J.; Casey, Clifton C.

2004-01-01

Crosswell radar methods can be used to dynamically image ground-water flow and mass transport associated with tracer tests, hydraulic tests, and natural physical processes, for improved characterization of preferential flow paths and complex aquifer heterogeneity. Unfortunately, because the raypath coverage of the interwell region is limited by the borehole geometry, the tomographic inverse problem is typically underdetermined, and tomograms may contain artifacts such as spurious blurring or streaking that confuse interpretation.We implement object-based inversion (using a constrained, non-linear, least-squares algorithm) to improve results from pixel-based inversion approaches that utilize regularization criteria, such as damping or smoothness. Our approach requires pre- and post-injection travel-time data. Parameterization of the image plane comprises a small number of objects rather than a large number of pixels, resulting in an overdetermined problem that reduces the need for prior information. The nature and geometry of the objects are based on hydrologic insight into aquifer characteristics, the nature of the experiment, and the planned use of the geophysical results.The object-based inversion is demonstrated using synthetic and crosswell radar field data acquired during vegetable-oil injection experiments at a site in Fridley, Minnesota. The region where oil has displaced ground water is discretized as a stack of rectangles of variable horizontal extents. The inversion provides the geometry of the affected region and an estimate of the radar slowness change for each rectangle. Applying petrophysical models to these results and porosity from neutron logs, we estimate the vegetable-oil emulsion saturation in various layers.Using synthetic- and field-data examples, object-based inversion is shown to be an effective strategy for inverting crosswell radar tomography data acquired to monitor the emplacement of vegetable-oil emulsions. A principal advantage of object-based inversion is that it yields images that hydrologists and engineers can easily interpret and use for model calibration.

Determination of Reaction Stoichiometries by Flow Injection Analysis.

ERIC Educational Resources Information Center

Rios, Angel; And Others

1986-01-01

Describes a method of flow injection analysis intended for calculation of complex-formation and redox reaction stoichiometries based on a closed-loop configuration. The technique is suitable for use in undergraduate laboratories. Information is provided for equipment, materials, procedures, and sample results. (JM)

A Nonlinear Dynamic Subscale Model for Partially Resolved Numerical Simulation (PRNS)/Very Large Eddy Simulation (VLES) of Internal Non-Reacting Flows

NASA Technical Reports Server (NTRS)

Shih, Tsan-Hsing; Liu, nan-Suey

2010-01-01

A brief introduction of the temporal filter based partially resolved numerical simulation/very large eddy simulation approach (PRNS/VLES) and its distinct features are presented. A nonlinear dynamic subscale model and its advantages over the linear subscale eddy viscosity model are described. In addition, a guideline for conducting a PRNS/VLES simulation is provided. Results are presented for three turbulent internal flows. The first one is the turbulent pipe flow at low and high Reynolds numbers to illustrate the basic features of PRNS/VLES; the second one is the swirling turbulent flow in a LM6000 single injector to further demonstrate the differences in the calculated flow fields resulting from the nonlinear model versus the pure eddy viscosity model; the third one is a more complex turbulent flow generated in a single-element lean direct injection (LDI) combustor, the calculated result has demonstrated that the current PRNS/VLES approach is capable of capturing the dynamically important, unsteady turbulent structures while using a relatively coarse grid.

Droplet-based microfluidic flow injection system with large-scale concentration gradient by a single nanoliter-scale injection for enzyme inhibition assay.

PubMed

Cai, Long-Fei; Zhu, Ying; Du, Guan-Sheng; Fang, Qun

2012-01-03

We described a microfluidic chip-based system capable of generating droplet array with a large scale concentration gradient by coupling flow injection gradient technique with droplet-based microfluidics. Multiple modules including sample injection, sample dispersion, gradient generation, droplet formation, mixing of sample and reagents, and online reaction within the droplets were integrated into the microchip. In the system, nanoliter-scale sample solution was automatically injected into the chip under valveless flow injection analysis mode. The sample zone was first dispersed in the microchannel to form a concentration gradient along the axial direction of the microchannel and then segmented into a linear array of droplets by immiscible oil phase. With the segmentation and protection of the oil phase, the concentration gradient profile of the sample was preserved in the droplet array with high fidelity. With a single injection of 16 nL of sample solution, an array of droplets with concentration gradient spanning 3-4 orders of magnitude could be generated. The present system was applied in the enzyme inhibition assay of β-galactosidase to preliminarily demonstrate its potential in high throughput drug screening. With a single injection of 16 nL of inhibitor solution, more than 240 in-droplet enzyme inhibition reactions with different inhibitor concentrations could be performed with an analysis time of 2.5 min. Compared with multiwell plate-based screening systems, the inhibitor consumption was reduced 1000-fold. © 2011 American Chemical Society

An initial investigation of multidimensional flow and transverse mixing characteristics of the Ohio River near Cincinnati, Ohio

USGS Publications Warehouse

Holtschlag, David J.

2009-01-01

Two-dimensional hydrodynamic and transport models were applied to a 34-mile reach of the Ohio River from Cincinnati, Ohio, upstream to Meldahl Dam near Neville, Ohio. The hydrodynamic model was based on the generalized finite-element hydrodynamic code RMA2 to simulate depth-averaged velocities and flow depths. The generalized water-quality transport code RMA4 was applied to simulate the transport of vertically mixed, water-soluble constituents that have a density similar to that of water. Boundary conditions for hydrodynamic simulations included water levels at the U.S. Geological Survey water-level gaging station near Cincinnati, Ohio, and flow estimates based on a gate rating at Meldahl Dam. Flows estimated on the basis of the gate rating were adjusted with limited flow-measurement data to more nearly reflect current conditions. An initial calibration of the hydrodynamic model was based on data from acoustic Doppler current profiler surveys and water-level information. These data provided flows, horizontal water velocities, water levels, and flow depths needed to estimate hydrodynamic parameters related to channel resistance to flow and eddy viscosity. Similarly, dye concentration measurements from two dye-injection sites on each side of the river were used to develop initial estimates of transport parameters describing mixing and dye-decay characteristics needed for the transport model. A nonlinear regression-based approach was used to estimate parameters in the hydrodynamic and transport models. Parameters describing channel resistance to flow (Manning’s “n”) were estimated in areas of deep and shallow flows as 0.0234, and 0.0275, respectively. The estimated RMA2 Peclet number, which is used to dynamically compute eddy-viscosity coefficients, was 38.3, which is in the range of 15 to 40 that is typically considered appropriate. Resulting hydrodynamic simulations explained 98.8 percent of the variability in depth-averaged flows, 90.0 percent of the variability in water levels, 93.5 percent of the variability in flow depths, and 92.5 percent of the variability in velocities. Estimates of the water-quality-transport-model parameters describing turbulent mixing characteristics converged to different values for the two dye-injection reaches. For the Big Indian Creek dye-injection study, an RMA4 Peclet number of 37.2 was estimated, which was within the recommended range of 15 to 40, and similar to the RMA2 Peclet number. The estimated dye-decay coefficient was 0.323. Simulated dye concentrations explained 90.2 percent of the variations in measured dye concentrations for the Big Indian Creek injection study. For the dye-injection reach starting downstream from Twelvemile Creek, however, an RMA4 Peclet number of 173 was estimated, which is far outside the recommended range. Simulated dye concentrations were similar to measured concentration distributions at the first four transects downstream from the dye-injection site that were considered vertically mixed. Farther downstream, however, simulated concentrations did not match the attenuation of maximum concentrations or cross-channel transport of dye that were measured. The difficulty of determining a consistent RMA4 Peclet was related to the two-dimension model assumption that velocity distributions are closely approximated by their depth-averaged values. Analysis of velocity data showed significant variations in velocity direction with depth in channel reaches with curvature. Channel irregularities (including curvatures, depth irregularities, and shoreline variations) apparently produce transverse currents that affect the distribution of constituents, but are not fully accounted for in a two-dimensional model. The two-dimensional flow model, using channel resistance to flow parameters of 0.0234 and 0.0275 for deep and shallow areas, respectively, and an RMA2 Peclet number of 38.3, and the RMA4 transport model with a Peclet number of 37.2, may have utility for emergency-planning purposes. Emergency-response efforts would be enhanced by continuous streamgaging records downstream from Meldahl Dam, real-time water-quality monitoring, and three-dimensional modeling. Decay coefficients are constituent specific.

Modeling of coulpled deformation and permeability evolution during fault reactivation induced by deep underground injection of CO2

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cappa, F.; Rutqvist, J.

2010-06-01

The interaction between mechanical deformation and fluid flow in fault zones gives rise to a host of coupled hydromechanical processes fundamental to fault instability, induced seismicity, and associated fluid migration. In this paper, we discuss these coupled processes in general and describe three modeling approaches that have been considered to analyze fluid flow and stress coupling in fault-instability processes. First, fault hydromechanical models were tested to investigate fault behavior using different mechanical modeling approaches, including slip interface and finite-thickness elements with isotropic or anisotropic elasto-plastic constitutive models. The results of this investigation showed that fault hydromechanical behavior can be appropriatelymore » represented with the least complex alternative, using a finite-thickness element and isotropic plasticity. We utilized this pragmatic approach coupled with a strain-permeability model to study hydromechanical effects on fault instability during deep underground injection of CO{sub 2}. We demonstrated how such a modeling approach can be applied to determine the likelihood of fault reactivation and to estimate the associated loss of CO{sub 2} from the injection zone. It is shown that shear-enhanced permeability initiated where the fault intersects the injection zone plays an important role in propagating fault instability and permeability enhancement through the overlying caprock.« less

Simple flow injection for determination of sulfite by amperometric detection using glassy carbon electrode modified with carbon nanotubes-PDDA-gold nanoparticles.

PubMed

Amatatongchai, Maliwan; Sroysee, Wongduan; Chairam, Sanoe; Nacapricha, Duangjai

2015-02-01

A new approach is presented for sensitive and selective measurement of sulfite (SO3(2-)) in beverages based on a simple flow injection system with amperometric detection. In this work, the sulfite sensor was a glassy carbon electrode modified with multiwall carbon nanotubes-poly(diallyldimethylammonium chloride)-gold nanoparticles composites (CNTs-PDDA-AuNPs/GC). Electrochemical oxidation of sulfite with this electrode was first studied in 0.1M phosphate buffer (pH 7.0) using cyclic voltammetry. The results indicated that the CNTs-PDDA-AuNPs/GC electrode possesses electrocatalytic activity for the oxidation of sulfite with high sensitivity and selectivity. Sulfite was quantified using amperometric measurement with the new sensor at +0.4V vs Ag/AgCl in conjunction with flow injection. The linear working range for the quantitation of sulfite was 2-200 mg L(-1) (r(2)=0.998) with a detection limit of 0.03 mg L(-1) (3σ of blank) and an estimated precision of 1.5%.The proposed method was successfully applied to the determination of sulfite in fruit juices and wines with a sample throughput of 23 samples per hour. Copyright © 2014 Elsevier B.V. All rights reserved.

CFD Modeling of Swirl and Nonswirl Gas Injections into Liquid Baths Using Top Submerged Lances

NASA Astrophysics Data System (ADS)

Huda, Nazmul; Naser, J.; Brooks, G.; Reuter, M. A.; Matusewicz, R. W.

2010-02-01

Fluid flow phenomena in a cylindrical bath stirred by a top submerged lance (TSL) gas injection was investigated by using the computational fluid dynamic (CFD) modeling technique for an isothermal air-water system. The multiphase flow simulation, based on the Euler-Euler approach, elucidated the effect of swirl and nonswirl flow inside the bath. The effects of the lance submergence level and the air flow rate also were investigated. The simulation results for the velocity fields and the generation of turbulence in the bath were validated against existing experimental data from the previous water model experimental study by Morsi et al.[1] The model was extended to measure the degree of the splash generation for different liquid densities at certain heights above the free surface. The simulation results showed that the two-thirds lance submergence level provided better mixing and high liquid velocities for the generation of turbulence inside the water bath. However, it is also responsible for generating more splashes in the bath compared with the one-third lance submergence level. An approach generally used by heating, ventilation, and air conditioning (HVAC) system simulations was applied to predict the convective mixing phenomena. The simulation results for the air-water system showed that mean convective mixing for swirl flow is more than twice than that of nonswirl in close proximity to the lance. A semiempirical equation was proposed from the results of the present simulation to measure the vertical penetration distance of the air jet injected through the annulus of the lance in the cylindrical vessel of the model, which can be expressed as L_{va} = 0.275( {do - di } )Frm^{0.4745} . More work still needs to be done to predict the detail process kinetics in a real furnace by considering nonisothermal high-temperature systems with chemical reactions.

Droplet-based magnetically activated cell separation: analysis of separation efficiency based on the variation of flow-induced circulation in a pendent drop.

PubMed

Kim, Youngho; Lee, Sang Ho; Kim, Byungkyu

2009-12-01

Under the assumption that separation efficiencies are mainly affected by the velocity of flow-induced circulation due to buffer injection in a pendent drop, this paper describes an analysis of the separation efficiency of a droplet-based magnetically activated cell separation (DMACS) system. To investigate the velocity of the flow-induced circulation, we supposed that numerous flows in a pendent drop could be considered as a "theoretically normalized" flow (or conceptually normalized flow, CNF) based on the Cauchy-Goursat theorem. With the morphological characteristics (length and duration time) of a pendent drop depending on the initial volume, we obtained the velocities of the CNF. By measuring the separation efficiencies for different initial volumes and by analyzing the separation efficiency in terms of the velocity of the CNF, we found that the separation efficiencies (in the case of a low rate of buffer injection; 5 and 15 microl x min(-1)) are mainly affected by the velocity of the CNF. Moreover, we confirmed that the phenomenological features of a pendent drop cause a fluctuation of its separation efficiencies over a range of specific volumes (initial volumes ranging from 40 to 80 microl), because of the "sweeping-off" phenomenon, that is, positive cells gathered into the positive fraction are forced to move away from the magnetic side by flow-induced circulation due to buffer injection. In addition, from the variation of the duration time, that is, the interval between the beginning of injection of the buffer solution and the time at which a pendent drop detaches, it could also be confirmed that a shorter duration time leads to decrease of the number of positive cells in negative fraction regardless of the rate of buffer injection (5, 15, and 50 microl x min(-1)). Therefore, if a DMACS system is operated with a 15 microl x min(-1) buffer injection flow rate and an initial volume of 80 microl or more, we would have the best efficiency of separation in the negative fraction.

A new approach to tracer transport analysis: From fracture systems to strongly heterogeneous porous media

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tsang, Chin-Fu

Many current development and utilization of groundwater resources include a study of their flow and transport properties. These properties are needed in evaluating possible changes in groundwater quality and potential transport of hazardous solutes through the groundwater system. Investigation of transport properties of fractured rocks is an active area of research. Most of the current approaches to the study of flow and transport in fractured rocks cannot be easily used for analysis of tracer transport field data. A new approach is proposed based on a detailed study of transport through a fracture of variable aperture. This is a two-dimensional stronglymore » heterogeneous permeable system. It is suggested that tracer breakthrough curves can be analyzed based on an aperture or permeability probability distribution function that characterizes the tracer flow through the fracture. The results are extended to a multi-fracture system and can be equally applied to a strongly heterogeneous porous medium. Finally, the need for multi-point or line and areal tracer injection and observation tests is indicated as a way to avoid the sensitive dependence of point measurements on local permeability variability. 30 refs., 15 figs.« less

Vortex dynamics studies in supersonic flow

NASA Astrophysics Data System (ADS)

Vergine, Fabrizio

This dissertation covers the study of selected vortex interaction scenarios both in cold and high enthalpy reacting flows. Specifically, the experimental results and the analysis of the flowfields resulting from two selected supersonic vortex interaction modes in a Mach 2.5 cold flow are presented. Additionally, the experiment design, based on vortex dynamics concepts, and the reacting plume survey of two pylon injectors in a Mach 2.4 high enthalpy flow are shown. All the cold flow experiments were conducted in the supersonic wind tunnel of the Aerodynamics Research Center at the University of Texas at Arlington. A strut injector equipped with specified ramp configurations was designed and used to produce the flowfields of interest. The reacting flow experiments were conducted in the the Expansion Tube Facility located in the High Temperature Gasdynamics Laboratory of Stanford University. A detailed description of the supersonic wind tunnel, the instrumentation, the strut injector and the supersonic wake flow downstream is shown as part of the characterization of the facility. As Stereoscopic Particle Image Velocimetry was the principal flow measurement technique used in this work to probe the streamwise vortices shed from ramps mounted on the strut, this dissertation provides a deep overview of the challenges and the application of the aforementioned technique to the survey of vortical flows. Moreover, the dissertation provides the comprehensive analysis of the mean and fluctuating velocity flowfields associated with two distinct vortex dynamics scenarios, as chosen by means of the outcomes of the simulations of a reduced order model developed in the research group. Specifically, the same streamwise vortices (strength, size and Reynolds number) were used experimentally to investigate both a case in which the resulting dynamics evolve in a vortex merging scenario and a case where the merging process is voluntarily avoided in order to focus the analysis on the fundamental differences associated with the amalgamation processes alone. The results from the mean flow highlight major differences between the two cases and will justify the use of the inviscid reduced order model used to predict the main flow physics. The analysis of the turbulence quantities based on concepts borrowed from incompressible turbulence theory explains interesting features of the fluctuating flowfields, suggesting that turbulence associated with the inspected flow conditions is essentially incompressible. Once the interactions among the vortical structures in cold flow were assessed, these vortex dynamics concepts were probed in a reacting environment. The dissertation describes the design phase of two pylon injectors based on the prediction capabilities of the aforementioned model. Then, the results of a set of combustion experiments conducted utilizing hydrogen fuel injected into Mach 2.4, high-enthalpy (2.8˜MJ/kg) air flow are discussed. The results show that, for the heat release levels considered in this study, the morphology of the plume and its evolution is very similar to the results produced by the code, enabling an interpretation of the phenomena based on vortex dynamics considerations. The persistence of the streamwise vortical structures created by the selected ramp configurations is shown together with the effectiveness of the coherent structures in successfully anchoring the flame very close to the injection point. The work shows the possibility of a new approach in the design of injection strategies (i.e., not limited to injection devices) suitable for adoption in scramjet combustors based on the ability to predict, with basic vortex dynamics concepts and a highly reduced computational cost, the main features of flows of technological interest.

Modeling of short fiber reinforced injection moulded composite

NASA Astrophysics Data System (ADS)

Kulkarni, A.; Aswini, N.; Dandekar, C. R.; Makhe, S.

2012-09-01

A micromechanics based finite element model (FEM) is developed to facilitate the design of a new production quality fiber reinforced plastic injection molded part. The composite part under study is composed of a polyetheretherketone (PEEK) matrix reinforced with 30% by volume fraction of short carbon fibers. The constitutive material models are obtained by using micromechanics based homogenization theories. The analysis is carried out by successfully coupling two commercial codes, Moldflow and ANSYS. Moldflow software is used to predict the fiber orientation by considering the flow kinetics and molding parameters. Material models are inputted into the commercial software ANSYS as per the predicted fiber orientation and the structural analysis is carried out. Thus in the present approach a coupling between two commercial codes namely Moldflow and ANSYS has been established to enable the analysis of the short fiber reinforced injection moulded composite parts. The load-deflection curve is obtained based on three constitutive material model namely an isotropy, transversely isotropy and orthotropy. Average values of the predicted quantities are compared to experimental results, obtaining a good correlation. In this manner, the coupled Moldflow-ANSYS model successfully predicts the load deflection curve of a composite injection molded part.

From medium heterogeneity to flow and transport: A time-domain random walk approach

NASA Astrophysics Data System (ADS)

Hakoun, V.; Comolli, A.; Dentz, M.

2017-12-01

The prediction of flow and transport processes in heterogeneous porous media is based on the qualitative and quantitative understanding of the interplay between 1) spatial variability of hydraulic conductivity, 2) groundwater flow and 3) solute transport. Using a stochastic modeling approach, we study this interplay through direct numerical simulations of Darcy flow and advective transport in heterogeneous media. First, we study flow in correlated hydraulic permeability fields and shed light on the relationship between the statistics of log-hydraulic conductivity, a medium attribute, and the flow statistics. Second, we determine relationships between Eulerian and Lagrangian velocity statistics, this means, between flow and transport attributes. We show how Lagrangian statistics and thus transport behaviors such as late particle arrival times are influenced by the medium heterogeneity on one hand and the initial particle velocities on the other. We find that equidistantly sampled Lagrangian velocities can be described by a Markov process that evolves on the characteristic heterogeneity length scale. We employ a stochastic relaxation model for the equidistantly sampled particle velocities, which is parametrized by the velocity correlation length. This description results in a time-domain random walk model for the particle motion, whose spatial transitions are characterized by the velocity correlation length and temporal transitions by the particle velocities. This approach relates the statistical medium and flow properties to large scale transport, and allows for conditioning on the initial particle velocities and thus to the medium properties in the injection region. The approach is tested against direct numerical simulations.

The Optimisation of Processing Condition for Injected Mould Polypropylene-Nanoclay-Gigantochloa Scortechinii based on Melt Flow Index

NASA Astrophysics Data System (ADS)

Othman, M. H.; Rosli, M. S.; Hasan, S.; Amin, A. M.; Hashim, M. Y.; Marwah, O. M. F.; Amin, S. Y. M.

2018-03-01

The fundamental knowledge of flow behaviour is essential in producing various plastic parts injection moulding process. Moreover, the adaptation of advanced polymer-nanocomposites such as polypropylene-nanoclay with natural fibres, for instance Gigantochloa Scortechinii may boost up the mechanical properties of the parts. Therefore, this project was proposed with the objective to optimise the processing condition of injected mould polypropylene-nanoclay-Gigantochloa Scortechini fibres based on the flow behaviour, which was melt flow index. At first, Gigantochloa Scortechinii fibres have to be preheated at temperature 120°C and then mixed with polypropylene, maleic anhydride modified polypropylene oligomers (PPgMA) and nanoclay by using Brabender Plastograph machine. Next, forms of pellets were produced from the samples by using Granulator machine for use in the injection moulding process. The design of experiments that was used in the injection moulding process was Taguchi Method Orthogonal Array -L934. Melt Flow Index (MF) was selected as the response. Based on the results, the value of MFI increased when the fiber content increase from 0% to 3%, which was 17.78 g/10min to 22.07 g/10min and decreased from 3% to 6%, which was 22.07 g/10min to 20.05 g/10min and 3%, which gives the highest value of MFI. Based on the signal to ratio analysis, the most influential parameter that affects the value of MFI was the melt temperature. The optimum parameter for 3% were 170°C melt temperature, 35% packing pressure, 30% screw speed and 3 second filling time.

Study on the Effect of water Injection Momentum on the Cooling Effect of Rocket Engine Exhaust Plume

NASA Astrophysics Data System (ADS)

Yang, Kan; Qiang, Yanhui; Zhong, Chenghang; Yu, Shaozhen

2017-10-01

For the study of water injection momentum factors impact on flow field of the rocket engine tail flame, the numerical computation model of gas-liquid two phase flow in the coupling of high temperature and high speed gas flow and low temperature liquid water is established. The accuracy and reliability of the numerical model are verified by experiments. Based on the numerical model, the relationship between the flow rate and the cooling effect is analyzed by changing the water injection momentum of the water spray pipes. And the effective mathematical expression is obtained. What’s more, by changing the number of the water spray and using small flow water injection, the cooling effect is analyzed to check the application range of the mathematical expressions. The results show that: the impact and erosion of the gas flow field could be reduced greatly by water injection, and there are two parts in the gas flow field, which are the slow cooling area and the fast cooling area. In the fast cooling area, the influence of the water flow momentum and nozzle quantity on the cooling effect can be expressed by mathematical functions without causing bifurcation flow for the mainstream gas. The conclusion provides a theoretical reference for the engineering application.

Determination of Acidity Constants by Gradient Flow-Injection Titration

ERIC Educational Resources Information Center

Conceicao, Antonio C. L.; Minas da Piedade, Manuel E.

2006-01-01

A three-hour laboratory experiment, designed for an advanced undergraduate course in instrumental analysis that illustrates the application of the gradient chamber flow-injection titration (GCFIT) method with spectrophotometric detection to determine acidity constants is presented. The procedure involves the use of an acid-base indicator to obtain…

Rapid and Automated Analytical Methods for Redox Species Based on Potentiometric Flow Injection Analysis Using Potential Buffers

PubMed Central

Ohura, Hiroki; Imato, Toshihiko

2011-01-01

Two analytical methods, which prove the utility of a potentiometric flow injection technique for determining various redox species, based on the use of some redox potential buffers, are reviewed. The first is a potentiometric flow injection method in which a redox couple such as Fe(III)-Fe(II), Fe(CN)6 3−-Fe(CN)(CN)6 4−, and bromide-bromine and a redox electrode or a combined platinum-bromide ion selective electrode are used. The analytical principle and advantages of the method are discussed, and several examples of its application are reported. Another example is a highly sensitive potentiometric flow injection method, in which a large transient potential change due to bromine or chlorine as an intermediate, generated during the reaction of the oxidative species with an Fe(III)-Fe(II) potential buffer containing bromide or chloride, is utilized. The analytical principle and details of the proposed method are described, and examples of several applications are described. The determination of trace amounts of hydrazine, based on the detection of a transient change in potential caused by the reaction with a Ce(IV)-Ce(III) potential buffer, is also described. PMID:21584280

A flow system for the spectrophotometric determination of lead in different types of waters using ion-exchange for pre-concentration and elimination of interferences.

PubMed

Mesquita, Raquel B R; Fernandes, Sílvia M V; Rangel, António O S S

2004-02-06

A flow system for the spectrophotometric determination of lead in natural and waste waters is proposed. The determination is based on the colorimetric reaction between malachite green and iodide, followed by the formation of a ternary complex between those reagents and lead cations. The developed flow system includes a lead pre-concentration step in a column packed with a cationic resin (Chelex 100) operating in a sequential injection mode. To improve the mixture of sample and reagents, a flow injection approach was adopted for the colorimetric determination. This way a hybrid flow system, involving both sequential and flow injection concepts was designed. Another feature of the proposed system is the efficient elimination of major interferent species, such as cadmium and copper. The elimination of cadmium interference is obtained by complexing Cd(2+) with chloride and retaining the formed negatively charged complexes in an anionic resin, AG1 X-8. As for copper, with the presence of both ionic resins as well as the conditions for cadmium elimination, it no longer acts as an interferent. Different ranges of lead concentration (50-300 and 300-1000mugl(-1)) can be determined with minor changes in the controlling software, useful for application to both natural and waste waters. Therefore, a detection limit of 25mugl(-1) was achieved. Repeatability was evaluated from 10 consecutive determinations being the results better than 4%. The recoveries of lead spikes added to the samples ranged from 93 to 102%. The sampling frequency was 17 and 24 determinations per hour, for 50-300 and 300-1000mugl(-1) ranges, respectively.

Flow injection method for sulphide determination using an organic mercury compound

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yaqoob, M.; Anwar, M.; Masood, A.S.

1991-04-01

A simple flow injection analysis method is described for the determination of soluble sulfide, based on the complexation of sulfide with p-hydroxymercurbenzoic acid, in the presence of dithizone used as an indicator. The reaction is very rapid, with a sampling rate of 90/hr. and requires a very short length post injection reaction coil. The detection limit and precision are 0.01 mM and 0.7%, respectively.

A multi-commuted flow injection system with a multi-channel propulsion unit placed before detection: Spectrophotometric determination of ammonium.

PubMed

Oliveira, Sara M; Lopes, Teresa I M S; Tóth, Ildikó V; Rangel, António O S S

2007-09-26

A flow system with a multi-channel peristaltic pump placed before the solenoid valves is proposed to overcome some limitations attributed to multi-commuted flow injection systems: the negative pressure can lead to the formation of unwanted air bubbles and limits the use of devices for separation processes (gas diffusion, dialysis or ion-exchange). The proposed approach was applied to the colorimetric determination of ammonium nitrogen. In alkaline medium, ammonium is converted into ammonia, which diffuses over the membrane, causing a pH change and subsequently a colour change in the acceptor stream (bromothymol blue solution). The system allowed the re-circulation of the acceptor solution and was applied to ammonium determination in surface and tap water, providing relative standard deviations lower than 1.5%. A stopped flow approach in the acceptor stream was adopted to attain a low quantification limit (42 microgL(-1)) and a linear dynamic range of 50-1000 microgL(-1) with a determination rate of 20 h(-1).

Theoretical aspects for estimating anisotropic saturated hydraulic conductivity from in-well or direct-push probe injection tests in uniform media

NASA Astrophysics Data System (ADS)

Klammler, Harald; Layton, Leif; Nemer, Bassel; Hatfield, Kirk; Mohseni, Ana

2017-06-01

Hydraulic conductivity and its anisotropy are fundamental aquifer properties for groundwater flow and transport modeling. Current in-well or direct-push field measurement techniques allow for relatively quick determination of general conductivity profiles with depth. However, capabilities for identifying local scale conductivities in the horizontal and vertical directions are very limited. Here, we develop the theoretical basis for estimating horizontal and vertical conductivities from different types of steady-state single-well/probe injection tests under saturated conditions and in the absence of a well skin. We explore existing solutions and a recent semi-analytical solution approach to the flow problem under the assumption that the aquifer is locally homogeneous. The methods are based on the collection of an additional piece of information in the form of a second injection (or recirculation) test at a same location, or in the form of an additional head or flow observation along the well/probe. Results are represented in dimensionless charts for partial validation against approximate solutions and for practical application to test interpretation. The charts further allow for optimization of a test configuration to maximize sensitivity to anisotropy ratio. The two methods most sensitive to anisotropy are found to be (1) subsequent injection from a lateral screen and from the bottom of an otherwise cased borehole, and (2) single injection from a lateral screen with an additional head observation along the casing. Results may also be relevant for attributing consistent divergences in conductivity measurements from different testing methods applied at a same site or location to the potential effects of anisotropy. Some practical aspects are discussed and references are made to existing methods, which appear easily compatible with the proposed procedures.

Numerical analysis of combustion characteristics of hybrid rocket motor with multi-section swirl injection

NASA Astrophysics Data System (ADS)

Li, Chengen; Cai, Guobiao; Tian, Hui

2016-06-01

This paper is aimed to analyse the combustion characteristics of hybrid rocket motor with multi-section swirl injection by simulating the combustion flow field. Numerical combustion flow field and combustion performance parameters are obtained through three-dimensional numerical simulations based on a steady numerical model proposed in this paper. The hybrid rocket motor adopts 98% hydrogen peroxide and polyethylene as the propellants. Multiple injection sections are set along the axis of the solid fuel grain, and the oxidizer enters the combustion chamber by means of tangential injection via the injector ports in the injection sections. Simulation results indicate that the combustion flow field structure of the hybrid rocket motor could be improved by multi-section swirl injection method. The transformation of the combustion flow field can greatly increase the fuel regression rate and the combustion efficiency. The average fuel regression rate of the motor with multi-section swirl injection is improved by 8.37 times compared with that of the motor with conventional head-end irrotational injection. The combustion efficiency is increased to 95.73%. Besides, the simulation results also indicate that (1) the additional injection sections can increase the fuel regression rate and the combustion efficiency; (2) the upstream offset of the injection sections reduces the combustion efficiency; and (3) the fuel regression rate and the combustion efficiency decrease with the reduction of the number of injector ports in each injection section.

Efficient and robust compositional two-phase reservoir simulation in fractured media

NASA Astrophysics Data System (ADS)

Zidane, A.; Firoozabadi, A.

2015-12-01

Compositional and compressible two-phase flow in fractured media has wide applications including CO2 injection. Accurate simulations are currently based on the discrete fracture approach using the cross-flow equilibrium model. In this approach the fractures and a small part of the matrix blocks are combined to form a grid cell. The major drawback is low computational efficiency. In this work we use the discrete-fracture approach to model the fractures where the fracture entities are described explicitly in the computational domain. We use the concept of cross-flow equilibrium in the fractures (FCFE). This allows using large matrix elements in the neighborhood of the fractures. We solve the fracture transport equations implicitly to overcome the Courant-Freidricks-Levy (CFL) condition in the small fracture elements. Our implicit approach is based on calculation of the derivative of the molar concentration of component i in phase (cαi ) with respect to the total molar concentration (ci ) at constant volume V and temperature T. This contributes to significant speed up of the code. The hybrid mixed finite element method (MFE) is used to solve for the velocity in both the matrix and the fractures coupled with the discontinuous Galerkin (DG) method to solve the species transport equations in the matrix, and a finite volume (FV) discretization in the fractures. In large scale problems the proposed approach is orders of magnitude faster than the existing models.

Flow behaviour of negatively buoyant jets in immiscible ambient fluid

NASA Astrophysics Data System (ADS)

Geyer, A.; Phillips, J. C.; Mier-Torrecilla, M.; Idelsohn, S. R.; Oñate, E.

2012-01-01

In this paper we investigate experimentally the injection of a negatively buoyant jet into a homogenous immiscible ambient fluid. Experiments are carried out by injecting a jet of dyed fresh water through a nozzle in the base of a cylindrical tank containing rapeseed oil. The fountain inlet flow rate and nozzle diameter were varied to cover a wide range of Richardson Ri (8 × 10-4 < Ri < 1.98), Reynolds Re (467 < Re < 5,928) and Weber We (2.40 < We < 308.56) numbers. Based on the Re, Ri and We values for the experiments, we have determined a regime map to define how these values may control the occurrence of the observed flow types. Whereas Ri plays a stronger role when determining the maximum penetration height, the effect of the Reynolds number is stronger predicting the flow behaviour for a specific nozzle diameter and injection velocity.

Continuous-Flow Production of Injectable Liposomes via a Microfluidic Approach

PubMed Central

Zizzari, Alessandra; Bianco, Monica; Perrone, Elisabetta; Amato, Francesco; Maruccio, Giuseppe; Rendina, Filippo; Arima, Valentina

2017-01-01

Injectable liposomes are characterized by a suitable size and unique lipid mixtures, which require time-consuming and nonstraightforward production processes. The complexity of the manufacturing methods may affect liposome solubility, the phase transition temperatures of the membranes, the average particle size, and the associated particle size distribution, with a possible impact on the drug encapsulation and release. By leveraging the precise steady-state control over the mixing of miscible liquids and a highly efficient heat transfer, microfluidic technology has proved to be an effective and direct methodology to produce liposomes. This approach results particularly efficient in reducing the number of the sizing steps, when compared to standard industrial methods. Here, Microfluidic Hydrodynamic Focusing chips were produced and used to form liposomes upon tuning experimental parameters such as lipids concentration and Flow-Rate-Ratios (FRRs). Although modelling evidenced the dependence of the laminar flow on the geometric constraints and the FRR conditions, for the specific formulation investigated in this study, the lipids concentration was identified as the primary factor influencing the size of the liposomes and their polydispersity index. This was attributed to a predominance of the bending elasticity modulus over the vesiculation index in the lipid mixture used. Eventually, liposomes of injectable size were produced using microfluidic one-pot synthesis in continuous flow. PMID:29232873

Fluid flow characteristics during polymer flooding

NASA Astrophysics Data System (ADS)

Yao, S. L.; Dou, H. E.; Wu, M.; Zhang, H. J.

2018-05-01

At present the main problems of polymer flooding is the high injection pressure which could not guarantee the later injection. In this paper the analyses of polymer’s physical properties and its solution’s variable movement characteristics in porous media reveal the inevitable trend of decrease in injection capacity and liquid production due to the increase of fluid viscosity and flow rate with more flow resistance. The injection rate makes the primary contribution to the active viscosity of the polymer solution in porous media. The higher injection rate, the greater shearing degradation and the more the viscosity loss. Besides the quantitative variation, the rate also changes qualitatively as that the injection rate demonstrates composite change of injection intensity and density. Due to the different adjustment function of the polymer solution on its injection profile, there should be different adjustment model of rates in such stages. Here in combination of the on-site recognitions, several conclusions and recommendations are made based on the study of the injection pattern adjustment during polymer flooding to improve the pressure distribution system, which would be a meaningful reference for extensive polymer flooding in the petroleum industry.

Analytical solutions to non-Fickian subsurface dispersion in uniform groundwater flow

USGS Publications Warehouse

Zou, S.; Xia, J.; Koussis, Antonis D.

1996-01-01

Analytical solutions are obtained by the Fourier transform technique for the one-, two-, and three-dimensional transport of a conservative solute injected instantaneously in a uniform groundwater flow. These solutions account for dispersive non-linearity caused by the heterogeneity of the hydraulic properties of aquifer systems and can be used as building blocks to construct solutions by convolution (principle of superposition) for source conditions other than slug injection. The dispersivity is assumed to vary parabolically with time and is thus constant for the entire system at any given time. Two approaches for estimating time-dependent dispersion parameters are developed for two-dimensional plumes. They both require minimal field tracer test data and, therefore, represent useful tools for assessing real-world aquifer contamination sites. The first approach requires mapped plume-area measurements at two specific times after the tracer injection. The second approach requires concentration-versus-time data from two sampling wells through which the plume passes. Detailed examples and comparisons with other procedures show that the methods presented herein are sufficiently accurate and easier to use than other available methods.

Simulation of Reclaimed-Water Injection and Pumping Scenarios and Particle-Tracking Analysis near Mount Pleasant, South Carolina

USGS Publications Warehouse

Petkewich, Matthew D.; Campbell, Bruce G.

2009-01-01

The effect of injecting reclaimed water into the Middendorf aquifer beneath Mount Pleasant, South Carolina, was simulated using a groundwater-flow model of the Coastal Plain Physiographic Province of South Carolina and parts of Georgia and North Carolina. Reclaimed water, also known as recycled water, is wastewater or stormwater that has been treated to an appropriate level so that the water can be reused. The scenarios were simulated to evaluate potential changes in groundwater flow and groundwater-level conditions caused by injecting reclaimed water into the Middendorf aquifer. Simulations included a Base Case and two injection scenarios. Maximum pumping rates were simulated as 6.65, 8.50, and 10.5 million gallons per day for the Base Case, Scenario 1, and Scenario 2, respectively. The Base Case simulation represents a non-injection estimate of the year 2050 groundwater levels for comparison purposes for the two injection scenarios. For Scenarios 1 and 2, the simulated injection of reclaimed water at 3 million gallons per day begins in 2012 and continues through 2050. The flow paths and time of travel for the injected reclaimed water were simulated using particle-tracking analysis. The simulations indicated a general decline of groundwater altitudes in the Middendorf aquifer in the Mount Pleasant, South Carolina, area between 2004 and 2050 for the Base Case and two injection scenarios. For the Base Case, groundwater altitudes generally declined about 90 feet from the 2004 groundwater levels. For Scenarios 1 and 2, although groundwater altitudes initially increased in the Mount Pleasant area because of the simulated injection, these higher groundwater levels declined as Mount Pleasant Waterworks pumping increased over time. When compared to the Base Case simulation, 2050 groundwater altitudes for Scenario 1 are between 15 feet lower to 23 feet higher for production wells, between 41 and 77 feet higher for the injection wells, and between 9 and 23 feet higher for observation wells in the Mount Pleasant area. When compared to the Base Case simulation, 2050 groundwater altitudes for Scenario 2 are between 2 and 106 feet lower for production wells and observation wells and between 11 and 27 feet higher for the injection wells in the Mount Pleasant area. Water budgets for the model area immediately surrounding the Mount Pleasant area were calculated for 2011 and for 2050. The largest flow component for the 2050 water budget in the Mount Pleasant area is discharge through wells at rates between 7.1 and 10.9 million gallons of water per day. This groundwater is replaced predominantly by between 6.0 and 7.8 million gallons per day of lateral groundwater flow within the Middendorf aquifer for the Base Case and two scenarios and through reclaimed-water injection of 3 million gallons per day for Scenarios 1 and 2. In addition, between 175,000 and 319,000 gallons of groundwater are removed from this area per day because of the regional hydraulic gradient. Additional sources of water to this area are groundwater storage releases at rates between 86,800 and 116,000 gallons per day and vertical flow from over- and underlying confining units at rates between 69,100 and 150,000 gallons per day. Reclaimed water injected into the Middendorf aquifer at three hypothetical injection wells moved to the Mount Pleasant Waterworks production wells in 18 to 256 years as indicated by particle-tracking simulations. Time of travel varied from 18 to 179 years for simulated conditions of 20 percent uniform aquifer porosity and between 25 to 256 years for 30 percent uniform aquifer porosity.

A two-dimensional cascade solution using minimized surface singularity density distributions - with application to film cooled turbine blades

NASA Technical Reports Server (NTRS)

Mcfarland, E.; Tabakoff, W.; Hamed, A.

1977-01-01

An investigation of the effects of coolant injection on the aerodynamic performance of cooled turbine blades is presented. The coolant injection is modeled in the inviscid irrotational adiabatic flow analysis through the cascade using the distributed singularities approach. The resulting integral equations are solved using a minimized surface singularity density criteria. The aerodynamic performance was evaluated using this solution in conjunction with an existing mixing theory analysis. The results of the present analysis are compared with experimental measurements in cold flow tests.

A microfluidic flow injection system for DNA assay with fluids driven by an on-chip integrated pump based on capillary and evaporation effects.

PubMed

Xu, Zhang-Run; Zhong, Chong-Hui; Guan, Yan-Xia; Chen, Xu-Wei; Wang, Jian-Hua; Fang, Zhao-Lun

2008-10-01

A miniaturized flow injection analysis (FIA) system integrating a micropump on a microfluidic chip based on capillary and evaporation effects was developed. The pump was made by fixing a filter paper plug with a vent tube at the channel end, it requires no peripheral equipment and provides steady flow in the microl min(-1) range for FIA operation. Valve-free sample injection was achieved at nanolitre level using an array of slotted vials. The practical applicability of the system was demonstrated by DNA assay with laser-induced fluorescence (LIF) detection. A precision of 1.6% RSD (10.0 ng microl(-1), n=15) was achieved with a sampling throughput of 76 h(-1) and sample consumption of 95 nl.

Exogenous factors contributing to column bed heterogeneity: Part 1: Consequences of 'air' injections in liquid chromatography.

PubMed

Samuelsson, Jörgen; Fornstedt, Torgny; Shalliker, Andrew

2015-08-07

It has been shown that not only the packing homogeneity, but also factors external to the column bed, such as, frits and distributors can have important effects on the column performance. This current communication is the first in a series focusing on the impact of exogenous factors on the column bed heterogeneity. This study is based on several observations by us and others that chromatographic runs often, for technical reasons, include more or less portions of air in the injections. It is therefore extremely important to find out the impact of air on the column performance, the reliability of the results derived from analyses where air was injected, and the effect on the column homogeneity. We used a photographic approach for visualising the air transport phenomena, and found that the air transport through the column is comprised of many different types of transport phenomena, such as laminal flow, viscous fingering like flows, channels and bulbs, and pulsations. More particularly, the air clouds within the column definitely interact in the adsorption, i.e. mobile phase adsorbed to the column surface is displaced. In addition, irrespective of the type of air transport phenomena, the air does not penetrate the column homogeneously. This process is strongly flow dependent. In this work we study air transport both in an analytical scale and a semi-prep column. Copyright © 2015. Published by Elsevier B.V.

Topology of Flow Separation on Three-Dimensional Bodies

NASA Technical Reports Server (NTRS)

Chapman, Gary T.; Yates, Leslie A.

1991-01-01

In recent years there has been extensive research on three-dimensional flow separation. There are two different approaches: the phenomenological approach and a mathematical approach using topology. These two approaches are reviewed briefly and the shortcomings of some of the past works are discussed. A comprehensive approach applicable to incompressible and compressible steady-state flows as well as incompressible unsteady flow is then presented. The approach is similar to earlier topological approaches to separation but is more complete and in some cases adds more emphasis to certain points than in the past. To assist in the classification of various types of flow, nomenclature is introduced to describe the skin-friction portraits on the surface. This method of classification is then demonstrated on several categories of flow to illustrate particular points as well as the diversity of flow separation. The categories include attached, two-dimensional separation and three different types of simple, three-dimensional primary separation, secondary separation, and compound separation. Hypothetical experiments are utilized to illustrate the topological terminology and its role in characterizing these flows. These hypothetical experiments use colored oil injected onto the surface at singular points in the skin-friction portrait. Actual flow-visualization information, if available, is used to corroborate the hypothetical examples.

Application of nanoscale zero-valent iron tracer to delineate groundwater flow paths between a screened well and an open well in fractured rock

NASA Astrophysics Data System (ADS)

Chuang, P. Y.; Chiu, Y.; Liou, Y. H.; Teng, M. H.; Chia, Y.

2016-12-01

Fracture flow is of importance for water resources as well as the investigation of contaminant pathways. In this study, a novel characterization approach of nanoscale zero-valent iron (nZVI) tracer test was developed to accurately identify the connecting fracture zones of preferential flow between a screened well and an open well. Iron nanoparticles are magnetic and can be attracted by a magnet. This feature make it possible to design a magnet array for attracting nZVI particles at the tracer inlet to characterize the location of incoming tracer in the observation well. This novel approach was tested at two experiment wells with well hydraulic connectivity in a hydrogeological research station in central Taiwan. A heat-pulse flowmeter can be used to detect changes in flow velocity for delineating permeable fracture zones in the borehole and providing the design basis for the tracer test. Then, the most permeable zone in the injection well was hydraulically isolated by well screen to prevent the injected nZVI particles from being stagnated at the hole bottom. Afterwards, another hydraulic test was implemented to re-examine the hydraulic connectivity between the two wells. When nZVI slurry was injected in the injection well, they migrated through connected permeable fractures to the observation well. A breakthrough curve, observed by the fluid conductivity sensor in the observation well, indicated the arrival of nZVI slurry. The iron nanoparticles attracted to the magnets in the observation well provide the position of tracer inlet, which corroborates well with the depth of a permeable zone delineated by the flowmeter. This article demonstrates the potential of nano-iron tracer test to provide the quantitative information of fracture flow paths in fractured rock.

Computational Investigation of Novel Tip Leakage Mitigation Methods for High Pressure Turbine Blades

NASA Technical Reports Server (NTRS)

Ibrahim, Mounir; Gupta, Abhinav; Shyam, Vikram

2014-01-01

This paper presents preliminary findings on a possible approach to reducing tip leakage losses. In this paper a computational study was conducted on the Energy Efficient Engine (EEE) High Pressure Turbine (HPT) rotor tip geometry using the commercial numerical solver ANSYS FLUENT. The flow solver was validated against aerodynamic data acquired in the NASA Transonic Turbine Blade Cascade facility. The scope of the ongoing study is to computationally investigate how the tip leakage and overall blade losses are affected by (1) injection from the tip near the pressure side, (2) injection from the tip surface at the camber line, and (3) injection from the tip surface into the tip separation bubble. The objective is to identify the locations on the tip surface at which to place appropriately configured blowing keeping in mind the film cooling application of tip blowing holes. The validation was conducted at Reynolds numbers of 85,000, 343,000, and 685,000 and at engine realistic flow conditions. The coolant injection simulations were conducted at a Reynolds number of 343,000 based on blade chord and inlet velocity and utilized the SST turbulence model in FLUENT. The key parameters examined are the number of jets, jet angle and jet location. A coolant to inlet pressure ratio of 1.0 was studied for angles of +30 deg, -30 deg, and 90 deg to the local free stream on the tip. For the 3 hole configuration, 3 holes spaced 3 hole diameters apart with length to diameter ratio of 1.5 were used. A simulation including 11 holes along the entire mean camber line is also presented (30 deg toward suction side). In addition, the effect of a single hole is also compared to a flat tip with no injection. The results provide insight into tip flow control methods and can be used to guide further investigation into tip flow control. As noted in past research it is concluded that reducing leakage flow is not necessarily synonymous with reducing losses due to leakage.

Computational Investigation of Novel Tip Leakage Mitigation Methods for High Pressure Turbine Blades

NASA Technical Reports Server (NTRS)

Ibrahim, Mounir; Gupta, Abhinav; Shyam, Vikram

2014-01-01

This paper presents preliminary findings on a possible approach to reducing tip leakage losses. In this paper a computational study was conducted on the EEE (Energy Efficient Engine) HPT (High Pressure Turbine) rotor tip geometry using the commercial numerical solver ANSYS FLUENT. The flow solver was validated against aerodynamic data acquired in the NASA Transonic Turbine Blade Cascade facility. The scope of the ongoing study is to computationally investigate how the tip leakage and overall blade losses are affected by 1. injection from the tip near the pressure side, 2. injection from the tip surface at the camber line, and 3. injection from the tip surface into the tip separation bubble. The objective is to identify the locations on the tip surface at which to place appropriately configured blowing keeping in mind the film cooling application of tip blowing holes. The validation was conducted at Reynolds numbers of 85,000, 343,000 and 685,000 and at engine realistic flow conditions. The coolant injection simulations were conducted at a Reynolds number of 343,000 based on blade chord and inlet velocity and utilized the SST turbulence model in FLUENT. The key parameters examined are the number of jets, jet angle and jet location. A coolant to inlet pressure ratio of 1.0 was studied for angles of +30 deg., -30 deg. and 90 deg. to the local free stream on the tip. For the 3 hole configuration, 3 holes spaced 3 hole diameters apart with length to diameter ratio of 1.5 were used. A simulation including 11 holes along the entire mean camber line is also presented (30 degrees toward suction side). In addition, the effect of a single hole is also compared to a flat tip with no injection. The results provide insight into tip flow control methods and can be used to guide further investigation into tip flow control. As noted in past research it is concluded that reducing leakage flow is not necessarily synonymous with reducing losses due to leakage.

Comparison of Series of Vugs and Non-vuggy Synthetic Porous Media on Formation Damage

NASA Astrophysics Data System (ADS)

Khan, H.; DiCarlo, D. A.; Prodanovic, M.

2017-12-01

Produced water reinjection (PWRI) is an established cost-effective oil field practice where produced water is injected without any cleanup, for water flooding or disposal. Resultantly the cost of fresh injection fluid and/or processing produced water is saved. A common problem with injection of unprocessed water is formation damage in the near injection zone due to solids (fines) entrapment, causing a reduction in permeability and porosity of the reservoir. Most studies have used homogeneous porous media with unimodal grain sizes, while real world porous media often has a wide range of pores, up to and including vugs in carbonaceous rocks. Here we fabricate a series of vugs in synthetic porous media by sintering glass beads with large dissolvable inclusions. The process is found to be repeatable, allowing a similar vug configuration to be tested for different flow conditions. Bi-modal glass bead particles (25 & 100 micron) are injected at two different flow rates and three different injection concentrations. Porosity, permeability and effluent concentration are determined using CT scanning, pressure measurements and particle counting (Coulter counter), respectively. Image analysis is performed on the CT images to determine the change in vug size for each flow condition. We find that for the same flow conditions, heterogeneous media with series of vugs have an equal or greater permeability loss compared to homogeneous porous media. A significant change in permeability is observed at the highest concentration and flow rate as more particles approach the filter quickly, resulting in a greater loss in permeability in the lower end of the core. Image analysis shows the highest loss in vug size occurs at the low flow rate and highest concentration. The lower vug is completely blocked for this flow case. For all flow cases lower values of porosity are observed after the core floods. At low flow rate and medium concentration, a drastic loss in porosity is observed in the lower part of the core, after the vuggy zone. This trough is also distinctly clear in the homogeneous core for the same flow conditions. This study focuses on understanding the effect of pore heterogeneity on formation damage. We conclude that more damage is done deeper in vuggy formations at high flow rates, resulting in shorter injection cycle prior to clean up.

Multiphase and multiscale approaches for modelling the injection of textured moulds

NASA Astrophysics Data System (ADS)

Nakhoul, Rebecca; Laure, Patrice; Silva, Luisa; Vincent, Michel

2016-10-01

Micro-injection moulding is frequently used for the mass production of devices in micro-medical technologies, micro-optics and micro-mechanics. This work focuses mainly on offering numerical tools to model the injection of micro-textured moulds. Such tools can predict the different filling scenarios of the micro-details and consequently offer optimal operating conditions (mould and melt temperatures, melt flow, stresses, etc.) to analyse the final part quality. To do so, a full Eulerian approach is used to model the injection of textured moulds at both the macroscopic and microscopic scales as usual industrial software cannot handle the filling of micro details. Since heat transfers with the mould are very relevant due to high cooling rates, the coupling between micro- and macro- simulations is primordial to insure a complete and accurate representation of textured mould injection.

Numerical Simulations of Two-Phase Reacting Flow in a Single-Element Lean Direct Injection (LDI) Combustor Using NCC

NASA Technical Reports Server (NTRS)

Liu, Nan-Suey; Shih, Tsan-Hsing; Wey, C. Thomas

2011-01-01

A series of numerical simulations of Jet-A spray reacting flow in a single-element lean direct injection (LDI) combustor have been conducted by using the National Combustion Code (NCC). The simulations have been carried out using the time filtered Navier-Stokes (TFNS) approach ranging from the steady Reynolds-averaged Navier-Stokes (RANS), unsteady RANS (URANS), to the dynamic flow structure simulation (DFS). The sub-grid model employed for turbulent mixing and combustion includes the well-mixed model, the linear eddy mixing (LEM) model, and the filtered mass density function (FDF/PDF) model. The starting condition of the injected liquid spray is specified via empirical droplet size correlation, and a five-species single-step global reduced mechanism is employed for fuel chemistry. All the calculations use the same grid whose resolution is of the RANS type. Comparisons of results from various models are presented.

Combustion of hydrogen injected into a supersonic airstream (a guide to the HISS computer program)

NASA Technical Reports Server (NTRS)

Dyer, D. F.; Maples, G.; Spalding, D. B.

1976-01-01

A computer program based on a finite-difference, implicit numerical integration scheme is described for the prediction of hydrogen injected into a supersonic airstream at an angle ranging from normal to parallel to the airstream main flow direction. Results of calculations for flow and thermal property distributions were compared with 'cold flow data' taken by NASA/Langley and show excellent correlation. Typical results for equilibrium combustion are presented and exhibit qualitatively plausible behavior. Computer time required for a given case is approximately one minute on a CDC 7600. A discussion of the assumption of parabolic flow in the injection region is given which demonstrates that improvement in calculation in this region could be obtained by a partially-parabolic procedure which has been developed. It is concluded that the technique described provides an efficient and reliable means for analyzing hydrogen injection into supersonic airstreams and the subsequent combustion.

Deposition and fine particle production during dynamic flow in a dry powder inhaler: a CFD approach.

PubMed

Milenkovic, J; Alexopoulos, A H; Kiparissides, C

2014-01-30

In this work the dynamic flow as well as the particle motion and deposition in a commercial dry powder inhaler, DPI (i.e., Turbuhaler) is described using computational fluid dynamics, CFD. The dynamic flow model presented here is an extension of a steady flow model previously described in Milenkovic et al. (2013). The model integrates CFD simulations for dynamic flow, an Eulerian-fluid/Lagrangian-particle description of particle motion as well as a particle/wall interaction model providing the sticking efficiency of particles colliding with the DPI walls. The dynamic flow is imposed by a time varying outlet pressure and the particle injections into the DPI are assumed to occur instantaneously and follow a prescribed particle size distribution, PSD. The total particle deposition and the production of fine particles in the DPI are determined for different peak inspiratory flow rates, PIFR, flow increase rates, FIR, and particle injection times. The simulation results for particle deposition are found to agree well with available experimental data for different values of PIFR and FIR. The predicted values of fine particle fraction are in agreement with available experimental results when the mean size of the injected PSD is taken to depend on the PIFR. Copyright © 2013 Elsevier B.V. All rights reserved.

Normal and reverse flow injection–spectrophotometric determination of thiamine hydrochloride in pharmaceutical preparations using diazotized metoclopramide

PubMed Central

Al Abachi, Mouayed Q.; Hadi, Hind

2012-01-01

Simple and sensitive normal and reverse flow injection methods for spectrophotometric determination of thiamine hydrochloride (THC) at the microgram level were proposed and optimized. Both methods are based on the reaction between THC and diazotized metoclopramide in alkaline medium. Beer’s law was obeyed over the range of 10–300 and 2–90 μg/mL, the limits of detection were 2.118 and 0.839 μg/mL and the sampling rates were 80 and 95 injections per hour for normal and reverse flow injection methods respectively. The application of both methods to commercially available pharmaceuticals produced acceptable results. The flow system is suitable for application in quality control processes. PMID:29403765

Non-Darcian flow of shear-thinning fluids through packed beads: Experiments and predictions using Forchheimer's law and Ergun's equation

NASA Astrophysics Data System (ADS)

Rodríguez de Castro, Antonio; Radilla, Giovanni

2017-02-01

The flow of shear-thinning fluids through unconsolidated porous media is present in a number of important industrial applications such as soil depollution, Enhanced Oil Recovery or filtration of polymeric liquids. Therefore, predicting the pressure drop-flow rate relationship in model porous media has been the scope of major research efforts during the last decades. Although the flow of Newtonian fluids through packs of spherical particles is well understood in most cases, much less is known regarding the flow of shear-thinning fluids as high molecular weight polymer aqueous solutions. In particular, the experimental data for the non-Darcian flow of shear-thinning fluids are scarce and so are the current approaches for their prediction. Given the relevance of non-Darcian shear-thinning flow, the scope of this work is to perform an experimental study to systematically evaluate the effects of fluid shear rheology on the flow rate-pressure drop relationships for the non-Darcian flow through different packs of glass spheres. To do so, xanthan gum aqueous solutions with different polymer concentrations are injected through four packs of glass spheres with uniform size under Darcian and inertial flow regimes. A total of 1560 experimental data are then compared with predictions coming from different methods based on the extension of widely used Ergun's equation and Forchheimer's law to the case of shear thinning fluids, determining the accuracy of these predictions. The use of a proper definition for Reynolds number and a realistic model to represent the rheology of the injected fluids results in the porous media are shown to be key aspects to successfully predict pressure drop-flow rate relationships for the inertial shear-thinning flow in packed beads.

Composite time-lapse computed tomography and micro finite element simulations: A new imaging approach for characterizing cement flows and mechanical benefits of vertebroplasty.

PubMed

Stadelmann, Vincent A; Zderic, Ivan; Baur, Annick; Unholz, Cynthia; Eberli, Ursula; Gueorguiev, Boyko

2016-02-01

Vertebroplasty has been shown to reinforce weak vertebral bodies and reduce fracture risks, yet cement leakage is a major problem that can cause severe complications. Since cement flow is nearly impossible to control during surgery, small volumes of cement are injected, but then mechanical benefits might be limited. A better understanding of cement flows within bone structure is required to further optimize vertebroplasty and bone augmentation in general. We developed a novel imaging method, composite time-lapse CT, to characterize cement flow during injection. In brief, composite-resolution time-lapse CT exploits the qualities of microCT and clinical CT. The method consists in overlaying low-resolution time-lapse CT scans acquired during injection onto pre-operative high-resolution microCT scans, generating composite-resolution time-lapse CT series of cement flow within bone. In this in vitro study, composite-resolution time-lapse CT was applied to eight intact and five artificially fractured cadaveric vertebrae during vertebroplasty. The time-lapse scans were acquired at one-milliliter cement injection steps until a total of 10 ml cement was injected. The composite-resolution series were then converted into micro finite element models to compute strains distribution under virtual axial loading. Relocation of strain energy density within bone structure was observed throughout the progression of the procedure. Interestingly, the normalized effect of cement injection on the overall stiffness of the vertebrae was similar between intact and fractured specimens, although at different orders of magnitude. In conclusion, composite time-lapse CT can picture cement flows during bone augmentation. The composite images can also be easily converted into finite element models to compute virtual strain distributions under loading at every step of an injection, providing deeper understanding on the biomechanics of vertebroplasty. Copyright © 2015 IPEM. Published by Elsevier Ltd. All rights reserved.

Fractal continuum model for tracer transport in a porous medium.

PubMed

Herrera-Hernández, E C; Coronado, M; Hernández-Coronado, H

2013-12-01

A model based on the fractal continuum approach is proposed to describe tracer transport in fractal porous media. The original approach has been extended to treat tracer transport and to include systems with radial and uniform flow, which are cases of interest in geoscience. The models involve advection due to the fluid motion in the fractal continuum and dispersion whose mathematical expression is taken from percolation theory. The resulting advective-dispersive equations are numerically solved for continuous and for pulse tracer injection. The tracer profile and the tracer breakthrough curve are evaluated and analyzed in terms of the fractal parameters. It has been found in this work that anomalous transport frequently appears, and a condition on the fractal parameter values to predict when sub- or superdiffusion might be expected has been obtained. The fingerprints of fractality on the tracer breakthrough curve in the explored parameter window consist of an early tracer breakthrough and long tail curves for the spherical and uniform flow cases, and symmetric short tailed curves for the radial flow case.

Determination of ambroxol hydrochloride, methylparaben and benzoic acid in pharmaceutical preparations based on sequential injection technique coupled with monolithic column.

PubMed

Satínský, Dalibor; Huclová, Jitka; Ferreira, Raquel L C; Montenegro, Maria Conceição B S M; Solich, Petr

2006-02-13

The porous monolithic columns show high performance at relatively low pressure. The coupling of short monoliths with sequential injection technique (SIA) results in a new approach to implementation of separation step to non-separation low-pressure method. In this contribution, a new separation method for simultaneous determination of ambroxol, methylparaben and benzoic acid was developed based on a novel reversed-phase sequential injection chromatography (SIC) technique with UV detection. A Chromolith SpeedROD RP-18e, 50-4.6 mm column with 10 mm precolumn and a FIAlab 3000 system with a six-port selection valve and 5 ml syringe were used for sequential injection chromatographic separations in our study. The mobile phase used was acetonitrile-tetrahydrofuran-0.05M acetic acid (10:10:90, v/v/v), pH 3.75 adjusted with triethylamine, flow rate 0.48 mlmin(-1), UV-detection was at 245 nm. The analysis time was <11 min. A new SIC method was validated and compared with HPLC. The method was found to be useful for the routine analysis of the active compounds ambroxol and preservatives (methylparaben or benzoic acid) in various pharmaceutical syrups and drops.

Induced seismicity closed-form traffic light system for actuarial decision-making during deep fluid injections.

PubMed

Mignan, A; Broccardo, M; Wiemer, S; Giardini, D

2017-10-19

The rise in the frequency of anthropogenic earthquakes due to deep fluid injections is posing serious economic, societal, and legal challenges to many geo-energy and waste-disposal projects. Existing tools to assess such problems are still inherently heuristic and mostly based on expert elicitation (so-called clinical judgment). We propose, as a complementary approach, an adaptive traffic light system (ATLS) that is function of a statistical model of induced seismicity. It offers an actuarial judgement of the risk, which is based on a mapping between earthquake magnitude and risk. Using data from six underground reservoir stimulation experiments, mostly from Enhanced Geothermal Systems, we illustrate how such a data-driven adaptive forecasting system could guarantee a risk-based safety target. The proposed model, which includes a linear relationship between seismicity rate and flow rate, as well as a normal diffusion process for post-injection, is first confirmed to be representative of the data. Being integrable, the model yields a closed-form ATLS solution that is both transparent and robust. Although simulations verify that the safety target is consistently ensured when the ATLS is applied, the model from which simulations are generated is validated on a limited dataset, hence still requiring further tests in additional fluid injection environments.

The role of flow injection analysis within the framework of an automated laboratory

PubMed Central

Stockwell, Peter B.

1990-01-01

Flow Injection Analysis (FIA) was invented at roughly the same time by two quite dissimilar research groups [1,2]. FIA was patented by both groups in 1974; a year also marked by the publication of the first book on automatic chemical analysis [3]. This book was a major undertaking for its authors and it is hoped that it has added to the knowledge of those analysts attempting to automate their work or to increase the level of computerization/automation and thus reduce staffing commitments. This review discusses the role of FIA in laboratory automation, the advantages and disadvantages of the FIA approach, and the part it could play in future developments. It is important to stress at the outset that the FIA approach is all too often closely paralleled with convention al continuous flow analysis (CFA). This is a mistake for many reasons, none the least of which because of the considerable success of the CFA approach in contrast to the present lack of penetration in the commercial market-place of FIA instrumentation. PMID:18925262

Technique for predicting high-frequency stability characteristics of gaseous-propellant combustors

NASA Technical Reports Server (NTRS)

Priem, R. J.; Jefferson, Y. S. Y.

1973-01-01

A technique for predicting the stability characteristics of a gaseous-propellant rocket combustion system is developed based on a model that assumes coupling between the flow through the injector and the oscillating chamber pressure. The theoretical model uses a lumped parameter approach for the flow elements in the injection system plus wave dynamics in the combustion chamber. The injector flow oscillations are coupled to the chamber pressure oscillations with a delay time. Frequency and decay (or growth) rates are calculated for various combustor design and operating parameters to demonstrate the influence of various parameters on stability. Changes in oxidizer design parameters had a much larger influence on stability than a similar change in fuel parameters. A complete description of the computer program used to make these calculations is given in an appendix.

Characterization and optimization of low cost microfluidic thread based electroanalytical device for micro flow injection analysis.

PubMed

Agustini, Deonir; Bergamini, Márcio F; Marcolino-Junior, Luiz Humberto

2017-01-25

The micro flow injection analysis (μFIA) is a powerful technique that uses the principles of traditional flow analysis in a microfluidic device and brings a number of improvements related to the consumption of reagents and samples, speed of analysis and portability. However, the complexity and cost of manufacturing processes, difficulty in integrating micropumps and the limited performance of systems employing passive pumps are challenges that must be overcome. Here, we present the characterization and optimization of a low cost device based on cotton threads as microfluidic channel to perform μFIA based on passive pumps with good analytical performance in a simple, easy and inexpensive way. The transport of solutions is made through cotton threads by capillary force facilitated by gravity. After studying and optimizing several features related to the device, were obtained a flow rate of 2.2 ± 0.1 μL s -1 , an analytical frequency of 208 injections per hour, a sample injection volume of 2.0 μL and a waste volume of approximately 40 μL per analysis. For chronoamperometric determination of naproxen, a detection limit of 0.29 μmol L -1 was reached, with a relative standard deviation (RSD) of 1.69% between injections and a RSD of 3.79% with five different devices. Thus, based on the performance presented by proposed microfluidic device, it is possible to overcome some limitations of the μFIA systems based on passive pumps and allow expansion in the use of this technique. Copyright © 2016 Elsevier B.V. All rights reserved.

Fast cholesterol detection using flow injection microfluidic device with functionalized carbon nanotubes based electrochemical sensor.

PubMed

Wisitsoraat, A; Sritongkham, P; Karuwan, C; Phokharatkul, D; Maturos, T; Tuantranont, A

2010-12-15

This work reports a new cholesterol detection scheme using functionalized carbon nanotube (CNT) electrode in a polydimethylsiloxane/glass based flow injection microfluidic chip. CNTs working, silver reference and platinum counter electrode layers were fabricated on the chip by sputtering and low temperature chemical vapor deposition methods. Cholesterol oxidase prepared in polyvinyl alcohol solution was immobilized on CNTs by in-channel flow technique. Cholesterol analysis based on flow injection chronoamperometric measurement was performed in 150-μm-wide and 150-μm-deep microchannels. Fast and sensitive real-time detection was achieved with high throughput of more than 60 samples per hour and small sample volume of 15 μl. The cholesterol sensor had a linear detection range between 50 and 400 mg/dl. In addition, low cross-sensitivities toward glucose, ascorbic acid, acetaminophen and uric acid were confirmed. The proposed system is promising for clinical diagnostics of cholesterol with high speed real-time detection capability, very low sample consumption, high sensitivity, low interference and good stability. Copyright © 2010 Elsevier B.V. All rights reserved.

Two-column sequential injection chromatography--new approach for fast and effective analysis and its comparison with gradient elution chromatography.

PubMed

Chocholous, Petr; Satínský, Dalibor; Sklenárová, Hana; Solich, Petr

2010-05-23

This work presents novel approach in low-pressure chromatography flow systems--two-column Sequential Injection Chromatography (2-C SIC) and its comparison with gradient elution chromatography on the same instrument. The system was equipped with two different chromatographic columns (connected to selection valve in parallel design) for isocratic separation and determination of all components in composed anti-inflammatory pharmaceutical preparation (tablets). The sample was first injected on the first column of length 30 mm where less retained analytes were separated and then the sample was injected on the second column of length 10 mm where more retained analytes were separated. The SIC system was based on a commercial SIChrom manifold (8-port high-pressure selection valve and medium-pressure syringe pump with 4 mL reservoir) (FIAlab, USA) with two commercially available monolithic columns the "first column" Chromolith Flash RP-18e (25 mm x 4.6 mm i.d. with guard column 5 mm x 4.6 mm i.d.) and the "second column" Chromolith RP-18e (10 mm x 4.6 mm i.d.) and CCD UV-vis detector USB 4000 with micro-volume 1.0 cm Z flow cell. Two mobile phases were used for analysis (one for each column). The mobile phase 1 used for elution of paracetamol, caffeine and salicylic acid (internal standard) was acetonitrile/water (10:90, v/v, the water part of pH 3.5 adjusted with acetic acid), flow rate was 0.9 mL min(-1) (volume 3.0 mL of mobile phase per analysis). The mobile phase 2 used for elution of propyphenazone was acetonitrile/water (30:70, v/v); flow rate was 1.2 mL min(-1) (volume 1.5 mL of mobile phase per analysis). Absorbance was monitored at 210 nm. Samples were prepared by dissolving of one tablet in 30% acetonitrile and 10 microL of filtered supernatant was injected on each column (2 x 10 microL). The chromatographic resolution between all compounds was >1.45 and analysis time was 5.5 min under the optimal conditions. Limits of detection were determined at 0.4 microg mL(-1) for paracetamol, at 0.5 microg mL(-1) for caffeine and at 0.7 microg mL(-1) for propyphenazone. The new two-column chromatographic set-up developed as an alternative approach to gradient elution chromatography shows evident advantages (time and solvent reduction more than one-third) as compared with single-column gradient SIC method with Chromolith Flash RP-18 (25 mm x 4.6 mm i.d. with guard column 5 mm x 4.6 mm i.d.). Copyright 2010 Elsevier B.V. All rights reserved.

Time-resolved fuel injector flow characterisation based on 3D laser Doppler vibrometry

NASA Astrophysics Data System (ADS)

Crua, Cyril; Heikal, Morgan R.

2014-12-01

Hydrodynamic turbulence and cavitation are known to play a significant role in high-pressure atomizers, but the small geometries and extreme operating conditions hinder the understanding of the flow’s characteristics. Diesel internal flow experiments are generally conducted using x-ray techniques or on transparent, and often enlarged, nozzles with different orifice geometries and surface roughness to those found in production injectors. In order to enable investigations of the fuel flow inside unmodified injectors, we have developed a new experimental approach to measure time-resolved vibration spectra of diesel nozzles using a 3D laser vibrometer. The technique we propose is based on the triangulation of the vibrometer and fuel pressure transducer signals, and enables the quantitative characterisation of quasi-cyclic internal flows without requiring modifications to the injector, the working fluid, or limiting the fuel injection pressure. The vibrometer, which uses the Doppler effect to measure the velocity of a vibrating object, was used to scan injector nozzle tips during the injection event. The data were processed using a discrete Fourier transform to provide time-resolved spectra for valve-closed-orifice, minisac and microsac nozzle geometries, and injection pressures ranging from 60 to 160 MPa, hence offering unprecedented insight into cyclic cavitation and internal mechanical dynamic processes. A peak was consistently found in the spectrograms between 6 and 7.5 kHz for all nozzles and injection pressures. Further evidence of a similar spectral peak was obtained from the fuel pressure transducer and a needle lift sensor mounted into the injector body. Evidence of propagation of the nozzle oscillations to the liquid sprays was obtained by recording high-speed videos of the near-nozzle diesel jet, and computing the fast Fourier transform for a number of pixel locations at the interface of the jets. This 6-7.5 kHz frequency peak is proposed to be the natural frequency for the injector’s main internal fuel line. Other spectral peaks were found between 35 and 45 kHz for certain nozzle geometries, suggesting that these particular frequencies may be linked to nozzle dependent cavitation phenomena.

On the application of the PFEM to droplet dynamics modeling in fuel cells

NASA Astrophysics Data System (ADS)

Ryzhakov, Pavel B.; Jarauta, Alex; Secanell, Marc; Pons-Prats, Jordi

2017-07-01

The Particle Finite Element Method (PFEM) is used to develop a model to study two-phase flow in fuel cell gas channels. First, the PFEM is used to develop the model of free and sessile droplets. The droplet model is then coupled to an Eulerian, fixed-grid, model for the airflow. The resulting coupled PFEM-Eulerian algorithm is used to study droplet oscillations in an air flow and droplet growth in a low-temperature fuel cell gas channel. Numerical results show good agreement with predicted frequencies of oscillation, contact angle, and deformation of injected droplets in gas channels. The PFEM-based approach provides a novel strategy to study droplet dynamics in fuel cells.

Determination of chloride in admixtures and aggregates for cement by a simple flow injection potentiometric system.

PubMed

Junsomboon, Jaroon; Jakmunee, Jaroon

2008-07-15

A simple flow injection system using three 3-way solenoid valves as an electric control injection valve and with a simple home-made chloride ion selective electrode based on Ag/AgCl wire as a sensor for determination of water soluble chloride in admixtures and aggregates for cement has been developed. A liquid sample or an extract was injected into a water carrier stream which was then merged with 0.1M KNO(3) stream and flowed through a flow cell where the solution will be in contact with the sensor, producing a potential change recorded as a peak. A calibration graph in range of 10-100 mg L(-1) was obtained with a detection limit of 2 mg L(-1). Relative standard deviations for 7 replicates injecting of 20, 60 and 90 mg L(-1) chloride solutions were 1.0, 1.2 and 0.6%, respectively. Sample throughput of 60 h(-1) was achieved with the consumption of 1 mL each of electrolyte solution and water carrier. The developed method was validated by the British Standard methods.

Study of Injection of Helium into Supersonic Air Flow Using Rayleigh Scattering

NASA Technical Reports Server (NTRS)

Seaholtz, Richard G.; Buggele, Alvin E.

1997-01-01

A study of the transverse injection of helium into a Mach 3 crossflow is presented. Filtered Rayleigh scattering is used to measure penetration and helium mole fraction in the mixing region. The method is based on planar molecular Rayleigh scattering using an injection-seeded, frequency-doubled ND:YAG pulsed laser and a cooled CCD camera. The scattered light is filtered with an iodine absorption cell to suppress stray laser light. Preliminary data are presented for helium mole fraction and penetration. Flow visualization images obtained with a shadowgraph and wall static pressure data in the vicinity of the injection are also presented.

Performance of J-33-A-21 and J-33-A-23 Compressors with and without Water Injection

NASA Technical Reports Server (NTRS)

Beede, William L.

1948-01-01

In an investigation of the J-33-A-21 and the J-33-A-23 compressors with and without water injection, it was discovered that the compressors reacted differently to water injection although they were physically similar. An analysis of the effect of water injection on compressor performance and the consequent effect on matching of the compressor and turbine components in the turbojet engine was made. The analysis of component matching is based on a turbine flow function defined as the product of the equivalent weight flow and the reciprocal of the compressor pressure ratio.

Flow injection analysis simulations and diffusion coefficient determination by stochastic and deterministic optimization methods.

PubMed

Kucza, Witold

2013-07-25

Stochastic and deterministic simulations of dispersion in cylindrical channels on the Poiseuille flow have been presented. The random walk (stochastic) and the uniform dispersion (deterministic) models have been used for computations of flow injection analysis responses. These methods coupled with the genetic algorithm and the Levenberg-Marquardt optimization methods, respectively, have been applied for determination of diffusion coefficients. The diffusion coefficients of fluorescein sodium, potassium hexacyanoferrate and potassium dichromate have been determined by means of the presented methods and FIA responses that are available in literature. The best-fit results agree with each other and with experimental data thus validating both presented approaches. Copyright © 2013 The Author. Published by Elsevier B.V. All rights reserved.

a Marker-Based Eulerian-Lagrangian Method for Multiphase Flow with Supersonic Combustion Applications

NASA Astrophysics Data System (ADS)

Fan, Xiaofeng; Wang, Jiangfeng

2016-06-01

The atomization of liquid fuel is a kind of intricate dynamic process from continuous phase to discrete phase. Procedures of fuel spray in supersonic flow are modeled with an Eulerian-Lagrangian computational fluid dynamics methodology. The method combines two distinct techniques and develops an integrated numerical simulation method to simulate the atomization processes. The traditional finite volume method based on stationary (Eulerian) Cartesian grid is used to resolve the flow field, and multi-component Navier-Stokes equations are adopted in present work, with accounting for the mass exchange and heat transfer occupied by vaporization process. The marker-based moving (Lagrangian) grid is utilized to depict the behavior of atomized liquid sprays injected into a gaseous environment, and discrete droplet model 13 is adopted. To verify the current approach, the proposed method is applied to simulate processes of liquid atomization in supersonic cross flow. Three classic breakup models, TAB model, wave model and K-H/R-T hybrid model, are discussed. The numerical results are compared with multiple perspectives quantitatively, including spray penetration height and droplet size distribution. In addition, the complex flow field structures induced by the presence of liquid spray are illustrated and discussed. It is validated that the maker-based Eulerian-Lagrangian method is effective and reliable.

Efficient flow injection and sequential injection methods for spectrophotometric determination of oxybenzone in sunscreens based on reaction with Ni(II).

PubMed

Chisvert, A; Salvador, A; Pascual-Martí, M C; March, J G

2001-04-01

Spectrophotometric determination of a widely used UV-filter, such as oxybenzone, is proposed. The method is based on the complexation reaction between oxybenzone and Ni(II) in ammoniacal medium. The stoichiometry of the reaction, established by the Job method, was 1:1. Reaction conditions were studied and the experimental parameters were optimized, for both flow injection (FI) and sequential injection (SI) determinations, with comparative purposes. Sunscreen formulations containing oxybenzone were analyzed by the proposed methods and results compared with those obtained by HPLC. Data show that both FI and SI procedures provide accurate and precise results. The ruggedness, sensitivity and LOD are adequate to the analysis requirements. The sample frequency obtained by FI is three-fold higher than that of SI analysis. SI is less reagent-consuming than FI.

Determination of dipyrone in pharmaceutical preparations based on the chemiluminescent reaction of the quinolinic hydrazide-H2O2-vanadium(IV) system and flow-injection analysis.

PubMed

Pradana Pérez, Juan A; Durand Alegría, Jesús S; Hernando, Pilar Fernández; Sierra, Adolfo Narros

2012-01-01

A rapid, economic and sensitive chemiluminescent method involving flow-injection analysis was developed for the determination of dipyrone in pharmaceutical preparations. The method is based on the chemiluminescent reaction between quinolinic hydrazide and hydrogen peroxide in a strongly alkaline medium, in which vanadium(IV) acts as a catalyst. Principal chemical and physical variables involved in the flow-injection system were optimized using a modified simplex method. The variations in the quantum yield observed when dipyrone was present in the reaction medium were used to determine the concentration of this compound. The proposed method requires no preconcentration steps and reliably quantifies dipyrone over the linear range 1-50 µg/mL. In addition, a sample throughput of 85 samples/h is possible. Copyright © 2011 John Wiley & Sons, Ltd.

Constructive Activation of Reservoir-Resident Microbes for Enhanced Oil Recovery

NASA Astrophysics Data System (ADS)

DeBruyn, R. P.

2017-12-01

Microbial communities living in subsurface oil reservoirs biodegrade oil, producing methane. If this process could create methane within the waterflooded pore spaces of an oilfield, the methane would be expected to remain and occupy pore space, decreasing water relative permeability, diverting water flow, and increasing oil recovery by expanding the swept zone of the waterflood. This approach was tested in an oilfield in northern Montana. Preliminary assessments were made of geochemical conditions and microbiological habitations. Then, a formulation of microbial activators, with composition tailored for the reservoir's conditions, was metered at low rates into the existing injection water system for one year. In the field, the responses observed included improved oil production performance; a slight increase in injection pressure; and increased time needed for tracers to move between injection and producing wells. We interpret these results to confirm that successful stimulation of the microbial community caused more methane to be created within the swept zone of the waterflooded reservoir. When the methane exsolved as water flowed between high-pressure injection and low-pressure production wells, the bubbles occupied pore space, reducing water saturation and relative permeability, and re-directing some water flow to "slower" unswept rock with lower permeability and higher oil saturation. In total, the waterflood's swept zone had been expanded to include previously-unflooded rock. This technology was applied in this field after screening based on careful anaerobic sampling, advanced microbiological analysis, and the ongoing success of its waterflood. No reservoir or geological or geophysical simulation models were employed, and physical modifications to field facilities were minor. This technology of utilizing existing microbial populations for enhanced oil recovery can therefore be considered for deployment into waterfloods where small scale, advanced maturity, or insufficiency of data make other technologies too expensive.

Significant association between sulfate-reducing bacteria and uranium-reducing microbial communities as revealed by a combined massively parallel sequencing-indicator species approach.

PubMed

Cardenas, Erick; Wu, Wei-Min; Leigh, Mary Beth; Carley, Jack; Carroll, Sue; Gentry, Terry; Luo, Jian; Watson, David; Gu, Baohua; Ginder-Vogel, Matthew; Kitanidis, Peter K; Jardine, Philip M; Zhou, Jizhong; Criddle, Craig S; Marsh, Terence L; Tiedje, James M

2010-10-01

Massively parallel sequencing has provided a more affordable and high-throughput method to study microbial communities, although it has mostly been used in an exploratory fashion. We combined pyrosequencing with a strict indicator species statistical analysis to test if bacteria specifically responded to ethanol injection that successfully promoted dissimilatory uranium(VI) reduction in the subsurface of a uranium contamination plume at the Oak Ridge Field Research Center in Tennessee. Remediation was achieved with a hydraulic flow control consisting of an inner loop, where ethanol was injected, and an outer loop for flow-field protection. This strategy reduced uranium concentrations in groundwater to levels below 0.126 μM and created geochemical gradients in electron donors from the inner-loop injection well toward the outer loop and downgradient flow path. Our analysis with 15 sediment samples from the entire test area found significant indicator species that showed a high degree of adaptation to the three different hydrochemical-created conditions. Castellaniella and Rhodanobacter characterized areas with low pH, heavy metals, and low bioactivity, while sulfate-, Fe(III)-, and U(VI)-reducing bacteria (Desulfovibrio, Anaeromyxobacter, and Desulfosporosinus) were indicators of areas where U(VI) reduction occurred. The abundance of these bacteria, as well as the Fe(III) and U(VI) reducer Geobacter, correlated with the hydraulic connectivity to the substrate injection site, suggesting that the selected populations were a direct response to electron donor addition by the groundwater flow path. A false-discovery-rate approach was implemented to discard false-positive results by chance, given the large amount of data compared.

Preliminary assessment of injection, storage, and recovery of freshwater in the lower Hawthorn aquifer, Cape Coral, Florida

USGS Publications Warehouse

Quinones-Aponte, Vicente; Wexler, Eliezer J.

1995-01-01

A preliminary assessment of subsurface injection, storage and recovery of fresh canal water was made in the naturally brackish lower Hawthorn aquifer in Cape Coral, southwestern Florida. A digital modeling approach was used for this preliminary assessment, incorporating available data on hydrologic conditions, aquifer properties, and water quality to simulate density-dependent ground-water flow and advective-dispersive transport of a conservative ground-water solute (chloride ion). A baseline simulation was used as reference to compare the effects of changing various operational factors on the recovery efficiency. A recovery efficiency of 64 percent was estimated for the baseline simulation. Based on the model, the recovery efficiency increases if the injection rate and recovery rates are increased and if the ratio of recovery rate to injection rate is increased. Recovery efficiency decreases if the amount of water injected is increased; slightly decreases if the storage time is increased; is not changed significantly if the water is injected to a specific flow zone; increases with successive cycles of injection, storage, and recovery; and decreases if the chloride concentrations in either the injection water or native aquifer water are increased. In everal hypothetical tests, the recovery efficiency fluctuated between 22 and about 100 percent. Two successive cycles could bring the recovery efficiency from 60 to about 80 percent. Interlayer solute mass movement across the upper and lower boundaries seems to be the most important factor affecting the recovery efficiency. A sensitivity analysis was performed applying a technique in which the change in the various factors and the corresponding model responses are normalized so that meaningful comparisons among the responses could be made. The general results from the sensitivity analysis indicated that the permeabilities of the upper and lower flow zones were the most important factors that produced the greatest changes in the relative sensitivity of the recovery efficiency. Almost equally significant changes occurred in the relative sensitivity of the recovery efficiency when all porosity values of the upper and lower flow zones and the leaky confining units and the vertical anisotropy ratio were changed. The advective factors are the most important in the Cape Coral area according to the sensitivity analysis. However, the dispersivity values used in the model were extrapolated from studies conducted at the nearby Lee County Water Treatment Plant, and these values might not be representative of the actual dispersive characteristics of the lower Hawthorn aquifer in the Cape Coral area.

Design and characterization of poly(dimethylsiloxane)-based valves for interfacing continuous-flow sampling to microchip electrophoresis.

PubMed

Li, Michelle W; Huynh, Bryan H; Hulvey, Matthew K; Lunte, Susan M; Martin, R Scott

2006-02-15

This work describes the fabrication and evaluation of a poly(dimethyl)siloxane (PDMS)-based device that enables the discrete injection of a sample plug from a continuous-flow stream into a microchannel for subsequent analysis by electrophoresis. Devices were fabricated by aligning valving and flow channel layers followed by plasma sealing the combined layers onto a glass plate that contained fittings for the introduction of liquid sample and nitrogen gas. The design incorporates a reduced-volume pneumatic valve that actuates (on the order of hundreds of milliseconds) to allow analyte from a continuously flowing sampling channel to be injected into a separation channel for electrophoresis. The injector design was optimized to include a pushback channel to flush away stagnant sample associated with the injector dead volume. The effect of the valve actuation time, the pushback voltage, and the sampling stream flow rate on the performance of the device was characterized. Using the optimized design and an injection frequency of 0.64 Hz showed that the injection process is reproducible (RSD of 1.77%, n = 15). Concentration change experiments using fluorescein as the analyte showed that the device could achieve a lag time as small as 14 s. Finally, to demonstrate the potential uses of this device, the microchip was coupled to a microdialysis probe to monitor a concentration change and sample a fluorescein dye mixture.

Filling of high aspect ratio micro features of a microfluidic flow cytometer chip using micro injection moulding

NASA Astrophysics Data System (ADS)

Zhang, Haoyang; Fang, Fengzhou; Gilchrist, Michael D.; Zhang, Nan

2018-07-01

Micro injection moulding has been demonstrated as one of the most efficient mass production technologies for manufacturing polymeric microfluidic devices, which have been widely used in life sciences, environmental and analytical fields and agro-food industries. However, the filling of micro features for typical microfluidic devices is complicated and not yet fully understood, which consequently restricts the chip development. In the present work, a microfluidic flow cytometer chip with essential high aspect ratio micro features was used as a typical model to study their filling process. Short-shot experiments and single factor experiments were performed to examine the filling progress of such features during the injection and packing stages of the micro injection moulding process. The influence of process parameters such as shot size, packing pressure, packing time and mould temperature were systematically monitored, characterised and correlated with 3D measurements and real response of the machine such as screw velocity and screw position. A combined melt flow and creep deformation model was proposed to explain the complex influence of process on replication. An approach of over-shot micro injection moulding was proposed and was shown to be effective at improving the replication quality of high aspect ratio micro features.

Implicit Coupling Approach for Simulation of Charring Carbon Ablators

NASA Technical Reports Server (NTRS)

Chen, Yih-Kanq; Gokcen, Tahir

2013-01-01

This study demonstrates that coupling of a material thermal response code and a flow solver with nonequilibrium gas/surface interaction for simulation of charring carbon ablators can be performed using an implicit approach. The material thermal response code used in this study is the three-dimensional version of Fully Implicit Ablation and Thermal response program, which predicts charring material thermal response and shape change on hypersonic space vehicles. The flow code solves the reacting Navier-Stokes equations using Data Parallel Line Relaxation method. Coupling between the material response and flow codes is performed by solving the surface mass balance in flow solver and the surface energy balance in material response code. Thus, the material surface recession is predicted in flow code, and the surface temperature and pyrolysis gas injection rate are computed in material response code. It is demonstrated that the time-lagged explicit approach is sufficient for simulations at low surface heating conditions, in which the surface ablation rate is not a strong function of the surface temperature. At elevated surface heating conditions, the implicit approach has to be taken, because the carbon ablation rate becomes a stiff function of the surface temperature, and thus the explicit approach appears to be inappropriate resulting in severe numerical oscillations of predicted surface temperature. Implicit coupling for simulation of arc-jet models is performed, and the predictions are compared with measured data. Implicit coupling for trajectory based simulation of Stardust fore-body heat shield is also conducted. The predicted stagnation point total recession is compared with that predicted using the chemical equilibrium surface assumption

Predicting ESI/MS Signal Change for Anions in Different Solvents.

PubMed

Kruve, Anneli; Kaupmees, Karl

2017-05-02

LC/ESI/MS is a technique widely used for qualitative and quantitative analysis in various fields. However, quantification is currently possible only for compounds for which the standard substances are available, as the ionization efficiency of different compounds in ESI source differs by orders of magnitude. In this paper we present an approach for quantitative LC/ESI/MS analysis without standard substances. This approach relies on accurately predicting the ionization efficiencies in ESI source based on a model, which uses physicochemical parameters of analytes. Furthermore, the model has been made transferable between different mobile phases and instrument setups by using a suitable set of calibration compounds. This approach has been validated both in flow injection and chromatographic mode with gradient elution.

A self-contained, automated methodology for optimal flow control validated for transition delay

NASA Technical Reports Server (NTRS)

Joslin, Ronald D.; Gunzburger, Max D.; Nicolaides, R. A.; Erlebacher, Gordon; Hussaini, M. Yousuff

1995-01-01

This paper describes a self-contained, automated methodology for flow control along with a validation of the methodology for the problem of boundary layer instability suppression. The objective of control is to match the stress vector along a portion of the boundary to a given vector; instability suppression is achieved by choosing the given vector to be that of a steady base flow, e.g., Blasius boundary layer. Control is effected through the injection or suction of fluid through a single orifice on the boundary. The present approach couples the time-dependent Navier-Stokes system with an adjoint Navier-Stokes system and optimality conditions from which optimal states, i.e., unsteady flow fields, and control, e.g., actuators, may be determined. The results demonstrate that instability suppression can be achieved without any a priori knowledge of the disturbance, which is significant because other control techniques have required some knowledge of the flow unsteadiness such as frequencies, instability type, etc.

Mathematical Modeling of Fluid Flow in a Water Physical Model of an Aluminum Degassing Ladle Equipped with an Impeller-Injector

NASA Astrophysics Data System (ADS)

Gómez, Eudoxio Ramos; Zenit, Roberto; Rivera, Carlos González; Trápaga, Gerardo; Ramírez-Argáez, Marco A.

2013-04-01

In this work, a 3D numerical simulation using a Euler-Euler-based model implemented into a commercial CFD code was used to simulate fluid flow and turbulence structure in a water physical model of an aluminum ladle equipped with an impeller for degassing treatment. The effect of critical process parameters such as rotor speed, gas flow rate, and the point of gas injection (conventional injection through the shaft vs a novel injection through the bottom of the ladle) on the fluid flow and vortex formation was analyzed with this model. The commercial CFD code PHOENICS 3.4 was used to solve all conservation equations governing the process for this two-phase fluid flow system. The mathematical model was reasonably well validated against experimentally measured liquid velocity and vortex sizes in a water physical model built specifically for this investigation. From the results, it was concluded that the angular speed of the impeller is the most important parameter in promoting better stirred baths and creating smaller and better distributed bubbles in the liquid. The pumping effect of the impeller is increased as the impeller rotation speed increases. Gas flow rate is detrimental to bath stirring and diminishes the pumping effect of the impeller. Finally, although the injection point was the least significant variable, it was found that the "novel" injection improves stirring in the ladle.

[Application of fingerprint chromatogram in quality control of Shen-Mai injection].

PubMed

Shi, Xian-zhe; Yang, Jun; Zhao, Chun-xia; Xiong, Jian-hui; Xu, Guo-wang

2002-07-01

The theory and practice of traditional Chinese medicine require some comprehensive methods to assess quality of the Chinese herbal medication. Fingerprint chromatogram is one of the feasible approaches to evaluate the quality of Chinese herbal medication. So the fingerprint chromatogram of Shen-Mai injection was established by using reversed-phase high performance liquid chromatography. The chromatographic conditions were as follows: a Hypersil C18 column was used; the mobile phase was composed of water (A) and acetontrile (B) with linear gradient elution (0-50 min, 5%-95% B, volume fraction); the flow rate was 1.0 mL/min and the UV absorbance detection was set at 202 nm. The peak-area ratios of twenty-three fingerprint peaks and internal standard (diphenyl) were taken as the criteria for quality control. The quality differences in various batches and various manufacturers of Shen-Mai injections were investigated by projection discriminance based on principal component analysis. The results show the method developed is convenient, reliable and applicable for the quality control analysis of Shen-Mai injection.

Effect of Trailing Edge Flow Injection on Fan Noise and Aerodynamic Performance

NASA Technical Reports Server (NTRS)

Fite, E. Brian; Woodward, Richard P.; Podboy, Gary G.

2006-01-01

An experimental investigation using trailing edge blowing for reducing fan rotor/guide vane wake interaction noise was completed in the NASA Glenn 9- by 15-foot Low Speed Wind Tunnel. Data were acquired to measure noise, aerodynamic performance, and flow features for a 22" tip diameter fan representative of modern turbofan technology. The fan was designed to use trailing edge blowing to reduce the fan blade wake momentum deficit. The test objective was to quantify noise reductions, measure impacts on fan aerodynamic performance, and document the flow field using hot-film anemometry. Measurements concentrated on approach, cutback, and takeoff rotational speeds as those are the primary conditions of acoustic interest. Data are presented for a 2% (relative to overall fan flow) trailing edge injection rate and show a 2 dB reduction in Overall Sound Power Level (OAPWL) at all fan test speeds. The reduction in broadband noise is nearly constant and is approximately 1.5 dB up to 20 kHz at all fan speeds. Measurements of tone noise show significant variation, as evidenced by reductions of up to 6 dB in the 2 BPF tone at 6700 rpm.: and increases of nearly 2 dB for the 4 BPF tone at approach speed. Aerodynamic performance measurements show the fan with 2 % injection has an overall efficiency that is comparable to the baseline fan and operates, as intended, with nearly the same pressure ratio and mass flow parameters. Hot-film measurements obtained at the approach operating condition indicate that mean blade wake filling in the tip region was not as significant as expected. This suggests that additional acoustic benefits could be realized if the trailing edge blowing could be modified to provide better filling of the wake momentum deficit. Nevertheless, the hot-film measurements indicate that the trailing edge blowing provided significant reductions in blade wake turbulence. Overall, these results indicate that further work may be required to fully understand the proper implementation of injecting flow at/near the trailing edge as a wake filling strategy. However, data do support the notion that noise reductions can be realized not only for tones but perhaps more importantly, also for broadband. Furthermore, the technique can be implemented without adversely effecting overall fan aerodynamic performance.

Optimized and validated flow-injection spectrophotometric analysis of topiramate, piracetam and levetiracetam in pharmaceutical formulations.

PubMed

Hadad, Ghada M; Abdel-Salam, Randa A; Emara, Samy

2011-12-01

Application of a sensitive and rapid flow injection analysis (FIA) method for determination of topiramate, piracetam, and levetiracetam in pharmaceutical formulations has been investigated. The method is based on the reaction with ortho-phtalaldehyde and 2-mercaptoethanol in a basic buffer and measurement of absorbance at 295 nm under flow conditions. Variables affecting the determination such as sample injection volume, pH, ionic strength, reagent concentrations, flow rate of reagent and other FIA parameters were optimized to produce the most sensitive and reproducible results using a quarter-fraction factorial design, for five factors at two levels. Also, the method has been optimized and fully validated in terms of linearity and range, limit of detection and quantitation, precision, selectivity and accuracy. The method was successfully applied to the analysis of pharmaceutical preparations.

The Stability and Interfacial Motion of Multi-layer Radial Porous Media and Hele-Shaw Flows

NASA Astrophysics Data System (ADS)

Gin, Craig; Daripa, Prabir

2017-11-01

In this talk, we will discuss viscous fingering instabilities of multi-layer immiscible porous media flows within the Hele-Shaw model in a radial flow geometry. We study the motion of the interfaces for flows with both constant and variable viscosity fluids. We consider the effects of using a variable injection rate on multi-layer flows. We also present a numerical approach to simulating the interface motion within linear theory using the method of eigenfunction expansion. We compare these results with fully non-linear simulations.

Re-injection feasibility study of fracturing flow-back fluid in shale gas mining

NASA Astrophysics Data System (ADS)

Kang, Dingyu; Xue, Chen; Chen, Xinjian; Du, Jiajia; Shi, Shengwei; Qu, Chengtun; Yu, Tao

2018-02-01

Fracturing flow-back fluid in shale gas mining is usually treated by re-injecting into formation. After treatment, the fracturing flow-back fluid is injected back into the formation. In order to ensure that it will not cause too much damage to the bottom layer, feasibility evaluations of re-injection of two kinds of fracturing fluid with different salinity were researched. The experimental research of the compatibility of mixed water samples based on the static simulation method was conducted. Through the analysis of ion concentration, the amount of scale buildup and clay swelling rate, the feasibility of re-injection of different fracturing fluid were studied. The result shows that the swelling of the clay expansion rate of treated fracturing fluid is lower than the mixed water of treated fracturing fluid and the distilled water, indicating that in terms of clay expansion rate, the treated fracturing flow-back fluid is better than that of water injection after re-injection. In the compatibility test, the maximum amount of fouling in the Yangzhou oilfield is 12mg/L, and the maximum value of calcium loss rate is 1.47%, indicating that the compatibility is good. For the fracturing fluid with high salinity in the Yanchang oilfield, the maximum amount of scaling is 72mg/L, and the maximum calcium loss rate is 3.50%, indicating that the compatibility is better.

An analytical study on groundwater flow in drainage basins with horizontal wells

NASA Astrophysics Data System (ADS)

Wang, Jun-Zhi; Jiang, Xiao-Wei; Wan, Li; Wang, Xu-Sheng; Li, Hailong

2014-06-01

Analytical studies on release/capture zones are often limited to a uniform background groundwater flow. In fact, for basin-scale problems, the undulating water table would lead to the development of hierarchically nested flow systems, which are more complex than a uniform flow. Under the premise that the water table is a replica of undulating topography and hardly influenced by wells, an analytical solution of hydraulic head is derived for a two-dimensional cross section of a drainage basin with horizontal injection/pumping wells. Based on the analytical solution, distributions of hydraulic head, stagnation points and flow systems (including release/capture zones) are explored. The superposition of injection/pumping wells onto the background flow field leads to the development of new internal stagnation points and new flow systems (including release/capture zones). Generally speaking, the existence of n injection/pumping wells would result in up to n new internal stagnation points and up to 2n new flow systems (including release/capture zones). The analytical study presented, which integrates traditional well hydraulics with the theory of regional groundwater flow, is useful in understanding basin-scale groundwater flow influenced by human activities.

Low gravity quenching of hot tubes with cryogens

NASA Technical Reports Server (NTRS)

Antar, Basil N.; Collins, Frank G.; Kawaji, M.

1992-01-01

An experimental proceedure for examining flow boiling in low gravity environment is presented. The proceedure involves both ground based and KC-135 flight experiments. Two experimental apparati were employed, one for studying subcooled liquid boiling and another for examining saturated liquid boiling. For the saturated flow experiments, liquid nitrogen was used while freon 113 was used for the subcooled flow experiments. The boiling phenomenon was investigated in both cases using flow visualization techniques as well as tube wall temperature measurements. The flow field in both cases was established by injecting cold liquid in a heated tube whose temperature was set above the saturation values. The tubes were both vertically and horizontally supported with the liquid injected from the lower end of the tube. The results indicate substantial differences in the flow patterns established during boiling between the ground based, (1-g), experiments and the flight experiments, (low-g). These differences in the flow patterns will be discussed and some explanations will be offered.

Statistical analysis of the induced Basel 2006 earthquake sequence: introducing a probability-based monitoring approach for Enhanced Geothermal Systems

NASA Astrophysics Data System (ADS)

Bachmann, C. E.; Wiemer, S.; Woessner, J.; Hainzl, S.

2011-08-01

Geothermal energy is becoming an important clean energy source, however, the stimulation of a reservoir for an Enhanced Geothermal System (EGS) is associated with seismic risk due to induced seismicity. Seismicity occurring due to the water injection at depth have to be well recorded and monitored. To mitigate the seismic risk of a damaging event, an appropriate alarm system needs to be in place for each individual experiment. In recent experiments, the so-called traffic-light alarm system, based on public response, local magnitude and peak ground velocity, was used. We aim to improve the pre-defined alarm system by introducing a probability-based approach; we retrospectively model the ongoing seismicity in real time with multiple statistical forecast models and then translate the forecast to seismic hazard in terms of probabilities of exceeding a ground motion intensity level. One class of models accounts for the water injection rate, the main parameter that can be controlled by the operators during an experiment. By translating the models into time-varying probabilities of exceeding various intensity levels, we provide tools which are well understood by the decision makers and can be used to determine thresholds non-exceedance during a reservoir stimulation; this, however, remains an entrepreneurial or political decision of the responsible project coordinators. We introduce forecast models based on the data set of an EGS experiment in the city of Basel. Between 2006 December 2 and 8, approximately 11 500 m3 of water was injected into a 5-km-deep well at high pressures. A six-sensor borehole array, was installed by the company Geothermal Explorers Limited (GEL) at depths between 300 and 2700 m around the well to monitor the induced seismicity. The network recorded approximately 11 200 events during the injection phase, more than 3500 of which were located. With the traffic-light system, actions where implemented after an ML 2.7 event, the water injection was reduced and then stopped after another ML 2.5 event. A few hours later, an earthquake with ML 3.4, felt within the city, occurred, which led to bleed-off of the well. A risk study was later issued with the outcome that the experiment could not be resumed. We analyse the statistical features of the sequence and show that the sequence is well modelled with the Omori-Utsu law following the termination of water injection. Based on this model, the sequence will last 31+29/-14 years to reach the background level. We introduce statistical models based on Reasenberg and Jones and Epidemic Type Aftershock Sequence (ETAS) models, commonly used to model aftershock sequences. We compare and test different model setups to simulate the sequences, varying the number of fixed and free parameters. For one class of the ETAS models, we account for the flow rate at the injection borehole. We test the models against the observed data with standard likelihood tests and find the ETAS model accounting for the on flow rate to perform best. Such a model may in future serve as a valuable tool for designing probabilistic alarm systems for EGS experiments.

Coupling Hydraulic Fracturing Propagation and Gas Well Performance for Simulation of Production in Unconventional Shale Gas Reservoirs

NASA Astrophysics Data System (ADS)

Wang, C.; Winterfeld, P. H.; Wu, Y. S.; Wang, Y.; Chen, D.; Yin, C.; Pan, Z.

2014-12-01

Hydraulic fracturing combined with horizontal drilling has made it possible to economically produce natural gas from unconventional shale gas reservoirs. An efficient methodology for evaluating hydraulic fracturing operation parameters, such as fluid and proppant properties, injection rates, and wellhead pressure, is essential for the evaluation and efficient design of these processes. Traditional numerical evaluation and optimization approaches are usually based on simulated fracture properties such as the fracture area. In our opinion, a methodology based on simulated production data is better, because production is the goal of hydraulic fracturing and we can calibrate this approach with production data that is already known. This numerical methodology requires a fully-coupled hydraulic fracture propagation and multi-phase flow model. In this paper, we present a general fully-coupled numerical framework to simulate hydraulic fracturing and post-fracture gas well performance. This three-dimensional, multi-phase simulator focuses on: (1) fracture width increase and fracture propagation that occurs as slurry is injected into the fracture, (2) erosion caused by fracture fluids and leakoff, (3) proppant subsidence and flowback, and (4) multi-phase fluid flow through various-scaled anisotropic natural and man-made fractures. Mathematical and numerical details on how to fully couple the fracture propagation and fluid flow parts are discussed. Hydraulic fracturing and production operation parameters, and properties of the reservoir, fluids, and proppants, are taken into account. The well may be horizontal, vertical, or deviated, as well as open-hole or cemented. The simulator is verified based on benchmarks from the literature and we show its application by simulating fracture network (hydraulic and natural fractures) propagation and production data history matching of a field in China. We also conduct a series of real-data modeling studies with different combinations of hydraulic fracturing parameters and present the methodology to design these operations with feedback of simulated production data. The unified model aids in the optimization of hydraulic fracturing design, operations, and production.

Vertical gas injection into liquid cross-stream beneath horizontal surfaces

NASA Astrophysics Data System (ADS)

Lee, In-Ho; Makiharju, Simo; Lee, Inwon; Perlin, Marc; Ceccio, Steve

2013-11-01

Skin friction drag reduction on flat bottomed ships and barges can be achieved by creating an air layer immediately beneath the horizontal surface. The simplest way of introducing the gas is through circular orifices; however the dynamics of gas injection into liquid cross-streams under horizontal surfaces is not well understood. Experiments were conducted to investigate the development of the gas topology following its vertical injection through a horizontal surface. The liquid cross-flow, orifice diameter and gas flow rate were varied to investigate the effect of different ratios of momentum fluxes. The testing was performed on a 4.3 m long and 0.73 m wide barge model with air injection through a hole in the transparent bottom hull. The incoming boundary layer was measured via a pitot tube. Downstream distance based Reynolds number at the injection location was 5 × 105 through 4 × 106 . To observe the flow topology, still images and video were recorded from above the model (i.e. through the transparent hull), from beneath the bottom facing upward, and from the side at an oblique angle. The transition point of the flow topology was determined and analyzed.

Electrochemical biotin detection based on magnetic beads and a new magnetic flow cell for screen printed electrode.

PubMed

Biscay, Julien; González García, María Begoña; Costa García, Agustín

2015-01-01

The use of the first flow-cell for magnetic assays with an integrated magnet is reported here. The flow injection analysis system (FIA) is used for biotin determination. The reaction scheme is based on a one step competitive assay between free biotin and biotin labeled with horseradish peroxidase (B-HRP). The mixture of magnetic beads modified with streptavidin (Strep-MB), biotin and B-HRP is left 15 min under stirring and then a washing step is performed. After that, 100 μL of the mixture is injected and after 30s 100 μL of 3,3',5,5'-Tetramethylbenzidine (TMB) is injected and the FIAgram is recorded applying a potential of -0.2V. The linear range obtained is from 0.01 to 1 nM of biotin and the sensitivity is 758 nA/nM. The modification and cleaning of the electrode are performed in an easy way due to the internal magnet of the flow cell. Copyright © 2014 Elsevier B.V. All rights reserved.

Simultaneous determination of choline and acetylcholine based on a trienzyme chemiluminometric biosensor in a single line flow injection system.

PubMed

Kiba, Nobutoshi; Ito, Seiji; Tachibana, Masaki; Tani, Kazue; Koizumi, Hitoshi

2003-12-01

A detector for the simultaneous determination of choline (Ch) and acetylcholine (ACh) based on a sensitive trienzyme chemiluminometric biosensor in a single line flow injection (FI) system is described. Immobilized choline oxidase (ChOx), immobilized peroxidase (POx), immobilized acetylcholinesterase, and coimmobilized ChOx/POx were packed, in turn, in a transparent ETFE tube (1 mm i.d., 75 cm) and the tube was placed in front of a photomultipier tube as a flow cell. Two-peak response was obtained by one injection of the sample solution. The first and second peaks were dependent on the concentrations of Ch and ACh, respectively. The influence of some experimental parameters such as flow rate, amounts of immobilized enzymes on the behavior of the sensor was studied in order to optimize the sensitivity, sample throughput and resolution. Calibration curves were linear at 1 - 1000 nM for Ch and 3 - 3000 nM for ACh. The sample throughput was 25/h without carryover. The FI system was applied to the simultaneous determination of Ch and ACh in rabbit brain tissue homogenates.

Pressure and Flow Rate Changes During Contrast Injections in Cerebral Angiography: Correlation to Reflux Length.

PubMed

Kovarovic, Brandon; Woo, Henry H; Fiorella, David; Lieber, Baruch B; Sadasivan, Chander

2018-03-01

Cerebral angiography involves the antegrade injection of contrast media through a catheter into the vasculature to visualize the region of interest under X-ray imaging. Depending on the injection and blood flow parameters, the bolus of contrast can propagate in the upstream direction and proximal to the catheter tip, at which point contrast is said to have refluxed. In this in vitro study, we investigate the relationship of fundamental hemodynamic variables to this phenomenon. Contrast injections were carried out under steady and pulsatile flow using various vessel diameters, catheter sizes, working fluid flow rates, and injection rates. The distance from the catheter tip to the proximal edge of the contrast bolus, called reflux length, was measured on the angiograms; the relation of this reflux length to different hemodynamic parameters was evaluated. Results show that contrast reflux occurs when the pressure distal to the catheter tip increases to be greater than the pressure proximal to the catheter tip. The ratio of this pressure difference to the baseline flow rate, called reflux resistance here, was linearly correlated to the normalized reflux length (reflux length/vessel diameter). Further, the ratio of blood flow to contrast fluid momentums, called the Craya-Curtet number, was correlated to the normalized reflux length via a sigmoid function. A sigmoid function was also found to be representative of the relationship between the ratio of the Reynolds numbers of blood flow to contrast and the normalized reflux length. As described by previous reports, catheter based contrast injections cause substantial increases in local flow and pressure. Contrast reflux should generally be avoided during standard antegrade angiography. Our study shows two specific correlations between contrast reflux length and baseline and intra-injection parameters that have not been published previously. Further studies need to be conducted to fully characterize the phenomena and to extract reliable indicators of clinical utility. Parameters relevant to cerebral angiography are studied here, but the essential principles are applicable to all angiographic procedures involving antegrade catheter injections.

A Novel Thermal Management Approach for Radial Foil Air Bearings

DTIC Science & Technology

2010-07-01

injection air. The tests were conducted at room temperature with the bearing operating at speeds from 20 to 50 krpm while supporting 222N. Two different...14  List of Tables Table 1. Bearing temperature results for the two injection air flows at three different operating...no further than the research stage (3, 4). However, during the last 15 years, more advanced, higher load capacity bearings and high temperature

A Very Large Eddy Simulation of the Nonreacting Flow in a Single-Element Lean Direct Injection Combustor Using PRNS with a Nonlinear Subscale Model

NASA Technical Reports Server (NTRS)

Shih, Tsan-Hsing; Liu, Nan-Suey

2009-01-01

Very large eddy simulation (VLES) of the nonreacting turbulent flow in a single-element lean direct injection (LDI) combustor has been successfully performed via the approach known as the partially resolved numerical simulation (PRNS/VLES) using a nonlinear subscale model. The grid is the same as the one used in a previous RANS simulation, which was considered as too coarse for a traditional LES simulation. In this study, we first carry out a steady RANS simulation to provide the initial flow field for the subsequent PRNS/VLES simulation. We have also carried out an unsteady RANS (URANS) simulation for the purpose of comparing its results with that of the PRNS/VLES simulation. In addition, these calculated results are compared with the experimental data. The present effort has demonstrated that the PRNS/VLES approach, while using a RANS type of grid, is able to reveal the dynamically important, unsteady large-scale turbulent structures occurring in the flow field of a single-element LDI combustor. The interactions of these coherent structures play a critical role in the dispersion of the fuel, hence, the mixing between the fuel and the oxidizer in a combustor.

Examination of the effect of blowing on the near-surface flow structure over a dimpled surface

NASA Astrophysics Data System (ADS)

Borchetta, C. G.; Martin, A.; Bailey, S. C. C.

2018-03-01

The near surface flow over a dimpled surface with flow injection through it was documented using time-resolved particle image velocimetry. The instantaneous flow structure, time-averaged statistics, and results from snapshot proper orthogonal decomposition were used to examine the coherent structures forming near the dimpled surface. In particular, the modifications made to the flow structures by the addition of flow injection through the surface were studied. It was observed that without flow injection, inclined flow structures with alternating vorticity from neighboring dimples are generated by the dimples and advect downstream. This behavior is coupled with fluid becoming entrained inside the dimples, recirculating and ejecting away from the surface. When flow injection was introduced through the surface, the flow structures became more disorganized, but some of the features of the semi-periodic structures observed without flow injection were preserved. The structures with flow injection appear in multiple wall-normal layers, formed from vortical structures shed from upstream dimples, with a corresponding increase in the size of the advecting structures. As a result of the more complex flow field observed with flow injection, there was an increase in turbulent kinetic energy and Reynolds shear stress, with the Reynolds shear stress representing an increase in vertical transport of momentum by sweeping and ejecting motions that were not present without flow injection.

Measurements of Skin Friction of the Compressible Turbulent Boundary Layer on a Cone with Foreign Gas Injection

NASA Technical Reports Server (NTRS)

Pappas, Constantine C.; Ukuno, Arthur F.

1960-01-01

Measurements of average skin friction of the turbulent boundary layer have been made on a 15deg total included angle cone with foreign gas injection. Measurements of total skin-friction drag were obtained at free-stream Mach numbers of 0.3, 0.7, 3.5, and 4.7 and within a Reynolds number range from 0.9 x 10(exp 6) to 5.9 x 10(exp 6) with injection of helium, air, and Freon-12 (CCl2F2) through the porous wall. Substantial reductions in skin friction are realized with gas injection within the range of Mach numbers of this test. The relative reduction in skin friction is in accordance with theory-that is, the light gases are most effective when compared on a mass flow basis. There is a marked effect of Mach number on the reduction of average skin friction; this effect is not shown by the available theories. Limited transition location measurements indicate that the boundary layer does not fully trip with gas injection but that the transition point approaches a forward limit with increasing injection. The variation of the skin-friction coefficient, for the lower injection rates with natural transition, is dependent on the flow Reynolds number and type of injected gas; and at the high injection rates the skin friction is in fair agreement with the turbulent boundary layer results.

Bubble Generation in a Continuous Liquid Flow Under Reduced Gravity Conditions

NASA Technical Reports Server (NTRS)

Pais, Salvatore Cezar

1999-01-01

The present work reports a study of bubble generation under reduced gravity conditions for both co-flow and cross-flow configurations. Experiments were performed aboard the DC-9 Reduced Gravity Aircraft at NASA Glenn Research Center, using an air-water system. Three different flow tube diameters were used: 1.27, 1.9, and 2.54 cm. Two different ratios of air injection nozzle to tube diameters were considered: 0.1 and 0.2. Gas and liquid volumetric flow rates were varied from 10 to 200 ml/s. It was experimentally observed that with increasing superficial liquid velocity, the bubbles generated decreased in size. The bubble diameter was shown to increase with increasing air injection nozzle diameters. As the tube diameter was increased, the size of the detached bubbles increased. Likewise, as the superficial liquid velocity was increased, the frequency of bubble formation increased and thus the time to detach forming bubbles decreased. Independent of the flow configuration (for either single nozzle or multiple nozzle gas injection), void fraction and hence flow regime transition can be controlled in a somewhat precise manner by solely varying the gas and liquid volumetric flow rates. On the other hand, it is observed that uniformity of bubble size can be controlled more accurately by using single nozzle gas injection than by using multiple port injection, since this latter system gives rise to unpredictable coalescence of adjacent bubbles. A theoretical model, based on an overall force balance, is employed to study single bubble generation in the dynamic and bubbly flow regime. Under conditions of reduced gravity, the gas momentum flux enhances bubble detachment; however, the surface tension forces at the nozzle tip inhibits bubble detachment. Liquid drag and inertia can act either as attaching or detaching force, depending on the relative velocity of the bubble with respect to the surrounding liquid. Predictions of the theoretical model compare well with performed experiments. However, at higher superficial,liquid velocities, the bubble neck length begins to significantly deviate from the value of the air injection nozzle diameter and thus the theory no longer predicts the experiment behavior. Effects of fluid properties, injection geometry and flow conditions on generated bubble size are investigated using the theoretical model. It is shown that bubble diameter is larger in a reduced gravity environment than in a normal gravity environment at similar flow condition and flow geometry.

Solute transport characterization in karst aquifers by tracer injection tests for a sustainable water resource management

NASA Astrophysics Data System (ADS)

Morales, T.; Angulo, B.; Uriarte, J. A.; Olazar, M.; Arandes, J. M.; Antiguedad, I.

2017-04-01

Protection of water resources is a major challenge today, given that territory occupation and land use are continuously increasing. In the case of karst aquifers, its dynamic complexity requires the use of specific methodologies that allow establishing local and regional flow and transport patterns. This information is particularly necessary when springs and wells harnessed for water supply are concerned. In view of the present state of the art, this work shows a new approach based on the use of a LiCl based tracer injection test through a borehole for transport characterization from a local to a regional scale. Thus a long term tracer injection test was conducted in a particularly sensitive sector of the Egino karst massif (Basque Country, Spain). The initial displacement of tracer in the vicinity of the injection was monitored in a second borehole at a radial distance of 10.24 m. This first information, assessed by a radial divergent model, allows obtaining transport characteristic parameters in this immediate vicinity during injection. At a larger (regional) scale, the tracer reaches a highly transmissive network with mean traveling velocities to the main springs being from 4.3 to 13.7 m/h. The responses obtained, particularly clear in the main spring used for water supply, and the persistence of part of the tracer in the injection zone, pose reconsidering the need for their protection. Thus, although the test allows establishing the 24-h isochrone, which is the ceiling value in present European vulnerability approaches, the results obtained advise widening the zone to protect in order to guarantee water quality in the springs. Overall, this stimulus-response test allows furthering the knowledge on the dynamics of solute transport in karst aquifers and is a particularly useful tool in studies related to source vulnerability and protection in such a complex medium.

Feasibility of utilizing bioindicators for testing microbial inactivation in sweetpotato purees processed with a continuous-flow microwave system.

PubMed

Brinley, T A; Dock, C N; Truong, V-D; Coronel, P; Kumar, P; Simunovic, J; Sandeep, K P; Cartwright, G D; Swartzel, K R; Jaykus, L-A

2007-06-01

Continuous-flow microwave heating has potential in aseptic processing of various food products, including purees from sweetpotatoes and other vegetables. Establishing the feasibility of a new processing technology for achieving commercial sterility requires evaluating microbial inactivation. This study aimed to assess the feasibility of using commercially available plastic pouches of bioindicators containing spores of Geobacillius stearothermophilus ATCC 7953 and Bacillus subtilis ATCC 35021 for evaluating the degree of microbial inactivation achieved in vegetable purees processed in a continuous-flow microwave heating unit. Sweetpotato puree seeded with the bioindicators was subjected to 3 levels of processing based on the fastest particles: undertarget process (F(0) approximately 0.65), target process (F(0) approximately 2.8), and overtarget process (F(0) approximately 10.10). After initial experiments, we found it was necessary to engineer a setup with 2 removable tubes connected to the continuous-flow microwave system to facilitate the injection of indicators into the unit without interrupting the puree flow. Using this approach, 60% of the indicators injected into the system could be recovered postprocess. Spore survival after processing, as evaluated by use of growth indicator dyes and standard plating methods, verified inactivation of the spores in sweetpotato puree. The log reduction results for B. subtilis were equivalent to the predesigned degrees of sterilization (F(0)). This study presents the first report suggesting that bioindicators such as the flexible, food-grade plastic pouches can be used for microbial validation of commercial sterilization in aseptic processing of foods using a continuous-flow microwave system.

Intramuscular injection technique: an evidence-based approach.

PubMed

Ogston-Tuck, Sherri

2014-09-30

Intramuscular injections require a thorough and meticulous approach to patient assessment and injection technique. This article, the second in a series of two, reviews the evidence base to inform safer practice and to consider the evidence for nursing practice in this area. A framework for safe practice is included, identifying important points for safe technique, patient care and clinical decision making. It also highlights the ongoing debate in selection of intramuscular injection sites, predominately the ventrogluteal and dorsogluteal muscles.

Enzymatic amplification of a flow-injected thermometric enzyme-linked immunoassay for human insulin.

PubMed

Mecklenburg, M; Lindbladh, C; Li, H; Mosbach, K; Danielsson, B

1993-08-01

A flow-injected thermometric enzyme linked immunoassay for human insulin which employs the lactate dehydrogenase/lactate oxidase (LDH/LOD) substrate recycling system for signal amplification is described. The system is composed of two columns, an immunosorbent column containing immobilized anti-insulin antibodies for sensing and a recycling column containing immobilized LDH/LOD/Catalase for detection. The effect of flow rates, conjugate concentrations, and chromatographic support material upon the sensitivity of the assay are investigated. The assay has a detection limit of 0.025 microgram/ml and a linear range from 0.05 to 2 micrograms/ml. This corresponds to a 10-fold increase in sensitivity over the unamplified system. A recombinant human insulin-proinsulin conjugate was also tested. The results show that enzymatic amplification can be employed to increase the sensitivity and reproducibility of flow injection assay-based biosensors. The implications of these results upon on-line analysis are discussed.

Application of Synthetic Jets to Reduce Stator Flow Separation in a Low Speed Axial Compressor

NASA Technical Reports Server (NTRS)

Braunscheidel, Edward P.; Culley, Dennis E.; Zaman, Khairul B.M.Q.

2008-01-01

Flow control using synthetic jet injection has been applied in a low speed axial compressor. The synthetic jets were applied from the suction surface of a stator vane via a span-wise row of slots pitched in the streamwise direction. Actuation was provided externally from acoustic drivers coupled to the vane tip via flexible tubing. The acoustic resonance characteristics of the system, and the resultant jet velocities were obtained. The effects on the separated flow field for various jet velocities and frequencies were explored. Total pressure loss reductions across the vane passage were measured. The effect of synthetic jet injection was shown to be comparable to that of pulsatory injection with mass addition for stator vanes which had separated flow. While only a weak dependence of the beneficial effect was noted based on the excitation frequency, a strong dependence on the amplitude was observed at all frequencies.

Coupled Viscous Fluid Flow and Joint Deformation Analysis for Grout Injection in a Rock Joint

NASA Astrophysics Data System (ADS)

Kim, Hyung-Mok; Lee, Jong-Won; Yazdani, Mahmoud; Tohidi, Elham; Nejati, Hamid Reza; Park, Eui-Seob

2018-02-01

Fluid flow modeling is a major area of interest within the field of rock mechanics. The main objective of this study is to gain insight into the performance of grout injection inside jointed rock masses by numerical modeling of grout flow through a single rock joint. Grout flow has been widely simulated using non-Newtonian Bingham fluid characterized by two main parameters of dynamic viscosity and shear yield strength both of which are time dependent. The increasing value of these properties with injection time will apparently affect the parameters representing the grouting performance including grout penetration length and volumetric injection rate. In addition, through hydromechanical coupling a mutual influence between the injection pressure from the one side and the joint opening/closing behavior and the aperture profile variation on the other side is anticipated. This is capable of producing a considerable impact on grout spread within the rock joints. In this study based on the Bingham fluid model, a series of numerical analysis has been conducted using UDEC to simulate the flow of viscous grout in a single rock joint with smooth parallel surfaces. In these analyses, the time-dependent evolution of the grout fluid properties and the hydromechanical coupling have been considered to investigate their impact on grouting performance. In order to verify the validity of these simulations, the results of analyses including the grout penetration length and the injection flow rate were compared with a well-known analytical solution which is available for the simple case of constant grout properties and non-coupled hydraulic analysis. The comparison demonstrated that the grout penetration length can be overestimated when the time-dependent hardening of grout material is not considered. Moreover, due to the HM coupling, it was shown that the joint opening induced by injection pressure may have a considerable increasing impression on the values of penetration length and injected grout volume.

Mixing enhancement strategies and their mechanisms in supersonic flows: A brief review

NASA Astrophysics Data System (ADS)

Huang, Wei

2018-04-01

Achieving efficient fuel-air mixing is a crucial issue in the design of the scramjet engine due to the compressibility effect on the mixing shear layer growth and the stringent flow residence time limitation induced by the high-speed crossflow, and the potential solution is to enhance mixing between air and fuel by introducing of streamwise vortices in the flow field. In this survey, some mixing enhancement strategies based on the traditional transverse injection technique proposed in recent years, as well as their mixing augmentation mechanisms, were reviewed in detail, namely the pulsed transverse injection scheme, the traditional transverse injection coupled with the vortex generator, and the dual transverse injection system with a front porthole and a rear air porthole arranged in tandem. The streamwise vortices, through the large-scale stirring motion that they introduce, are responsible for the extraction of large amounts of energy from the mean flow that can be converted into turbulence, ultimately leading to increased mixing effectiveness. The streamwise vortices may be obtained by taking advantage of the shear layer between a jet and the cross stream or by employing intrusive physical devices. Finally, a promising mixing enhancement strategy in supersonic flows was proposed, and some remarks were provided.

Nonlinear MHD simulation of current drive by multi-pulsed coaxial helicity injection in spherical torus

NASA Astrophysics Data System (ADS)

Kanki, Takashi; Nagata, Masayoshi; Kagei, Yasuhiro

2011-10-01

The dynamics of structures of magnetic field, current density, and plasma flow generated during multi-pulsed coaxial helicity injection in spherical torus is investigated by 3-D nonlinear MHD simulations. During the driven phase, the flux and current amplifications occur due to the merging and magnetic reconnection between the preexisting plasma in the confinement region and the ejected plasma from the gun region involving the n = 1 helical kink distortion of the central open flux column (COFC). Interestingly, the diamagnetic poloidal flow which tends toward the gun region is then observed due to the steep pressure gradients of the COFC generated by ohmic heating through an injection current winding around the inboard field lines, resulting in the formation of the strong poloidal flow shear at the interface between the COFC and the core region. This result is consistent with the flow shear observed in the HIST. During the decay phase, the configuration approaches the axisymmetric MHD equilibrium state without flow because of the dissipation of magnetic fluctuation energy to increase the closed flux surfaces, suggesting the generation of ordered magnetic field structure. The parallel current density λ concentrated in the COFC then diffuses to the core region so as to reduce the gradient in λ, relaxing in the direction of the Taylor state.

Trends in Flow-based Biosensing Systems for Pesticide Assessment

PubMed Central

Prieto-Simón, Beatriz; Campàs, Mònica; Andreescu, Silvana; Marty, Jean-Louis

2006-01-01

This review gives a survey on the state of the art of pesticide detection using flow-based biosensing systems for sample screening. Although immunosensor systems have been proposed as powerful pesticide monitoring tools, this review is mainly focused on enzyme-based biosensors, as they are the most commonly employed when using a flow system. Among the different detection methods able to be integrated into flow-injection analysis (FIA) systems, the electrochemical ones will be treated in more detail, due to their high sensitivity, simple sample pretreatment, easy operational procedures and real-time detection. During the last decade, new trends have been emerging in order to increase the enzyme stability, the sensitivity and selectivity of the measurements, and to lower the detection limits. These approaches are based on (i) the design of novel matrices for enzyme immobilisation, (ii) new manifold configurations of the FIA system, sometimes including miniaturisation or lab-on-chip protocols thanks to micromachining technology, (iii) the use of cholinesterase enzymes either from various commercial sources or genetically modified with the aim of being more sensitive, (iv) the incorporation of other highly specific enzymes, such as organophosphate hydrolase (OPH) or parathion hydrolase (PH) and (v) the combination of different electrochemical methods of detection. This article discusses these novel strategies and their advantages and limitations.

Quantification of the transient mass flow rate in a simplex swirl injector

NASA Astrophysics Data System (ADS)

Khil, Taeock; Kim, Sunghyuk; Cho, Seongho; Yoon, Youngbin

2009-07-01

When a heat release and acoustic pressure fluctuations are generated in a combustor by irregular and local combustions, these fluctuations affect the mass flow rate of the propellants injected through the injectors. In addition, variations of the mass flow rate caused by these fluctuations bring about irregular combustion, which is associated with combustion instability, so it is very important to identify a mass variation through the pressure fluctuation on the injector and to investigate its transfer function. Therefore, quantification of the variation of the mass flow rate generated in a simplex swirl injector via the injection pressure fluctuation was the subject of an initial study. To acquire the transient mass flow rate in the orifice with time, the axial velocity of flows and the liquid film thickness in the orifice were measured. The axial velocity was acquired through a theoretical approach after measuring the pressure in the orifice. In an effort to understand the flow area in the orifice, the liquid film thickness was measured by an electric conductance method. In the results, the mass flow rate calculated from the axial velocity and the liquid film thickness measured by the electric conductance method in the orifice was in good agreement with the mass flow rate acquired by the direct measuring method in a small error range within 1% in the steady state and within 4% for the average mass flow rate in a pulsated state. Also, the amplitude (gain) of the mass flow rate acquired by the proposed direct measuring method was confirmed using the PLLIF technique in the low pressure fluctuation frequency ranges with an error under 6%. This study shows that our proposed method can be used to measure the mass flow rate not only in the steady state but also in the unsteady state (or the pulsated state). Moreover, this method shows very high accuracy based on the experimental results.

Investigation of Wall Shear Stress Behavior for Rough Surfaces with Blowing

NASA Astrophysics Data System (ADS)

Helvey, Jacob; Borchetta, Colby; Miller, Mark; Martin, Alexandre; Bailey, Sean

2014-11-01

We present an experimental study conducted in a turbulent channel flow wind tunnel to determine the modifications made to the turbulent flow over rough surfaces with flow injection through the surfaces. Hot-wire profile results from a quasi-two-dimensional, sinusoidally-rough surface indicate that the effects of roughness are enhanced by momentum injection through the surface. In particular, the wall shear stress was found to show behavior consistent with increased roughness height when surface blowing was increased. This observed behavior contradicts previously reported results for regular three-dimensional roughness which show a decrease in wall shear stress with additional blowing. It is unclear whether this discrepancy is due to differences in the roughness geometry under consideration or the use of the Clauser fit to estimate wall shear stress. Additional PIV experiments are being conducted for a three-dimensional fibrous surface to obtain Reynolds shear stress profiles. These results provide an additional method for estimation of wall-shear stress and thus allow verification of the use of the Clauser chart approach for flows with momentum injection through the surface. This research is supported by NASA Kentucky EPSCoR Award NNX10AV39A, and NASA RA Award NNX13AN04A.

Determination of albumin in bronchoalveolar lavage fluid by flow-injection fluorometry using chromazurol S.

PubMed

Sato, Takaji; Saito, Yoshihiro; Chikuma, Masahiko; Saito, Yutaka; Nagai, Sonoko

2008-03-01

A highly sensitive flow injection fluorometry for the determination of albumin was developed and applied to the determination of albumin in human bronchoalveolar lavage fluids (BALF). This method is based on binding of chromazurol S (CAS) to albumin. The calibration curve was linear in the range of 5-200 microg/ml of albumin. A highly linear correlation (r=0.986) was observed between the albumin level in BALF samples (n=25) determined by the proposed method and by a conventional fluorometric method using CAS (CAS manual method). The IgG interference was lower in the CAS flow injection method than in the CAS manual method. The albumin level in BALF collected from healthy volunteers (n=10) was 58.5+/-13.1 microg/ml. The albumin levels in BALF samples obtained from patients with sarcoidosis and idiopathic pulmonary fibrosis were increased. This finding shows that the determination of albumin levels in BALF samples is useful for investigating lung diseases and that CAS flow injection method is promising in the determination of trace albumin in BALF samples, because it is sensitive and precise.

Development of a split-flow system for high precision variable sample introduction in supercritical fluid chromatography.

PubMed

Sakai, Miho; Hayakawa, Yoshihiro; Funada, Yasuhiro; Ando, Takashi; Fukusaki, Eiichiro; Bamba, Takeshi

2017-09-15

In this study, we propose a novel variable sample injection system based on full-loop injection, named the split-flow sample introduction system, for application in supercritical fluid chromatography (SFC). In this system, the mobile phase is split by the differential pressure between two back pressure regulators (BPRs) after full-loop injection suitable for SFC, and this differential pressure determines the introduction rate. Nine compounds with a wide range of characteristics were introduced with high reproducibility and universality, confirming that a robust variable sample injection system was achieved. We also investigated the control factors of our proposed system. Sample introduction was controlled by the ratio between the column-side pressure drops in splitless and split flow, ΔP columnsideinsplitless and ΔP columnsideinsplit , respectively, where ΔP columnsideinsplitless is related to the mobile phase flow rate and composition and the column resistance. When all other conditions are kept constant, increasing the make-up flow induces an additional pressure drop on the column side of the system, which leads to a reduced column-side flow rate, and hence decreased the amount of sample injected, even when the net pressure drop on the column side remains the same. Thus, sample introduction could be highly controlled at low sample introduction rate, regardless of the introduction conditions. This feature is advantageous because, as a control factor, the solvent in the make-up pump is independent of the column-side pressure drop. Copyright © 2017. Published by Elsevier B.V.

Experimental investigation of a supersonic swept ramp injector using laser-induced iodine fluorescence

NASA Technical Reports Server (NTRS)

Hartfield, Roy J.; Hollo, Steven D.; Mcdaniel, James C.

1990-01-01

Planar measurements of injectant mole fraction and temperature have been conducted in a nonreacting supersonic combustor configured with underexpanded injection in the base of a swept ramp. The temperature measurements were conducted with a Mach 2 test section inlet in streamwise planes perpendicular to the test section wall on which the ramp was mounted. Injection concentration measurements, conducted in cross flow planes with both Mach 2 and Mach 2.9 free stream conditions, dramatically illustrate the domination of the mixing process by streamwise vorticity generated by the ramp. These measurements, conducted using a nonintrusive optical technique (laser-induced iodine fluorescence), provide an accurate and extensive experimental data base for the validation of computation fluid dynamic codes for the calculation of highly three-dimensional supersonic combustor flow fields.

Photo-actuation of liquids for light-driven microfluidics: state of the art and perspectives.

PubMed

Baigl, Damien

2012-10-07

Using light to control liquid motion is a new paradigm for the actuation of microfluidic systems. We review here the different principles and strategies to induce or control liquid motion using light, which includes the use of radiation pressure, optical tweezers, light-induced wettability gradients, the thermocapillary effect, photosensitive surfactants, the chromocapillary effect, optoelectrowetting, photocontrolled electroosmotic flows and optical dielectrophoresis. We analyze the performance of these approaches to control using light many kinds of microfluidic operations involving discrete pL- to μL-sized droplets (generation, driving, mixing, reaction, sorting) or fluid flows in microchannels (valve operation, injection, pumping, flow rate control). We show that a complete toolbox is now available to control microfluidic systems by light. We finally discuss the perspectives of digital optofluidics as well as microfluidics based on all optical fluidic chips and optically reconfigurable devices.

Integrating a dual-silicon photoelectrochemical cell into a redox flow battery for unassisted photocharging.

PubMed

Liao, Shichao; Zong, Xu; Seger, Brian; Pedersen, Thomas; Yao, Tingting; Ding, Chunmei; Shi, Jingying; Chen, Jian; Li, Can

2016-05-04

Solar rechargeable flow cells (SRFCs) provide an attractive approach for in situ capture and storage of intermittent solar energy via photoelectrochemical regeneration of discharged redox species for electricity generation. However, overall SFRC performance is restricted by inefficient photoelectrochemical reactions. Here we report an efficient SRFC based on a dual-silicon photoelectrochemical cell and a quinone/bromine redox flow battery for in situ solar energy conversion and storage. Using narrow bandgap silicon for efficient photon collection and fast redox couples for rapid interface charge injection, our device shows an optimal solar-to-chemical conversion efficiency of ∼5.9% and an overall photon-chemical-electricity energy conversion efficiency of ∼3.2%, which, to our knowledge, outperforms previously reported SRFCs. The proposed SRFC can be self-photocharged to 0.8 V and delivers a discharge capacity of 730 mAh l(-1). Our work may guide future designs for highly efficient solar rechargeable devices.

A dilute-and-shoot flow-injection tandem mass spectrometry method for quantification of phenobarbital in urine.

PubMed

Alagandula, Ravali; Zhou, Xiang; Guo, Baochuan

2017-01-15

Liquid chromatography/tandem mass spectrometry (LC/MS/MS) is the gold standard of urine drug testing. However, current LC-based methods are time consuming, limiting the throughput of MS-based testing and increasing the cost. This is particularly problematic for quantification of drugs such as phenobarbital, which is often analyzed in a separate run because they must be negatively ionized. This study examined the feasibility of using a dilute-and-shoot flow-injection method without LC separation to quantify drugs with phenobarbital as a model system. Briefly, a urine sample containing phenobarbital was first diluted by 10 times, followed by flow injection of the diluted sample to mass spectrometer. Quantification and detection of phenobarbital were achieved by an electrospray negative ionization MS/MS system operated in the multiple reaction monitoring (MRM) mode with the stable-isotope-labeled drug as internal standard. The dilute-and-shoot flow-injection method developed was linear with a dynamic range of 50-2000 ng/mL of phenobarbital and correlation coefficient > 0.9996. The coefficients of variation and relative errors for intra- and inter-assays at four quality control (QC) levels (50, 125, 445 and 1600 ng/mL) were 3.0% and 5.0%, respectively. The total run time to quantify one sample was 2 min, and the sensitivity and specificity of the method did not deteriorate even after 1200 consecutive injections. Our method can accurately and robustly quantify phenobarbital in urine without LC separation. Because of its 2 min run time, the method can process 720 samples per day. This feasibility study shows that the dilute-and-shoot flow-injection method can be a general way for fast analysis of drugs in urine. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

Dynamic cone beam CT angiography of carotid and cerebral arteries using canine model

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cai Weixing; Zhao Binghui; Conover, David

2012-01-15

Purpose: This research is designed to develop and evaluate a flat-panel detector-based dynamic cone beam CT system for dynamic angiography imaging, which is able to provide both dynamic functional information and dynamic anatomic information from one multirevolution cone beam CT scan. Methods: A dynamic cone beam CT scan acquired projections over four revolutions within a time window of 40 s after contrast agent injection through a femoral vein to cover the entire wash-in and wash-out phases. A dynamic cone beam CT reconstruction algorithm was utilized and a novel recovery method was developed to correct the time-enhancement curve of contrast flow.more » From the same data set, both projection-based subtraction and reconstruction-based subtraction approaches were utilized and compared to remove the background tissues and visualize the 3D vascular structure to provide the dynamic anatomic information. Results: Through computer simulations, the new recovery algorithm for dynamic time-enhancement curves was optimized and showed excellent accuracy to recover the actual contrast flow. Canine model experiments also indicated that the recovered time-enhancement curves from dynamic cone beam CT imaging agreed well with that of an IV-digital subtraction angiography (DSA) study. The dynamic vascular structures reconstructed using both projection-based subtraction and reconstruction-based subtraction were almost identical as the differences between them were comparable to the background noise level. At the enhancement peak, all the major carotid and cerebral arteries and the Circle of Willis could be clearly observed. Conclusions: The proposed dynamic cone beam CT approach can accurately recover the actual contrast flow, and dynamic anatomic imaging can be obtained with high isotropic 3D resolution. This approach is promising for diagnosis and treatment planning of vascular diseases and strokes.« less

Bio-mimetic Flow Control

NASA Astrophysics Data System (ADS)

Choi, Haecheon

2009-11-01

Bio-mimetic engineering or bio-mimetics is the application of biological methods and systems found in nature to the study and design of engineering systems and modern technology (from Wikipedia). The concept itself is old, but successful developments have been made recently, especially in the research field of flow control. The objective of flow control based on the bio-mimetic approach is to develop novel concepts for reducing drag, increasing lift and enhancing aerodynamic performance. For skin friction reduction, a few ideas have been suggested such as the riblet from shark, compliant surface from dolphin, microbubble injection and multiple front-body curvature from penguin, and V-shaped protrusion from sailfish. For form drag reduction, several new attempts have been also made recently. Examples include the V-shaped spanwise grooves from saguaro cactus, overall shape of box fish, longitudinal grooves on scallop shell, bill of swordfish, hooked comb on owl wing, trailing-edge protrusion on dragonfly wing, and fillet. For the enhancement of aerodynamic performance, focuses have been made on the birds, fish and insects: e.g., double layered feather of landing bird, leading-edge serration of humpback-whale flipper, pectoral fin of flying fish, long tail on swallowtail-butterfly wing, wing flapping motion of dragonfly, and alula in birds. Living animals adapt their bodies to better performance in multi purposes, but engineering requires single purpose in most cases. Therefore, bio-mimetic approaches often produce excellent results more than expected. However, they are sometimes based on people's wrong understanding of nature and produce unwanted results. Successes and failures from bio-mimetic approaches in flow control will be discussed in the presentation.

The evolution of cooling flows. I - Self-similar cluster flows. [of gas in intergalactic medium

NASA Technical Reports Server (NTRS)

Chevalier, Roger A.

1987-01-01

The evolution of a cooling flow from an initial state of hydrostatic equilibrium in a cluster of galaxies is investigated. After gas mass and energy are injected into the cluster at an early phase, the gas approaches hydrostatic equilibrium over most of the cluster and cooling becomes important in the dense central regions. As time passes, cooling strongly affects an increasing amount of gas. The effects of mass removal from the flow, the inclusion of magnetic or cosmic-ray pressure, and heat conduction are considered individually.

Modified Beer-Lambert law for blood flow

NASA Astrophysics Data System (ADS)

Baker, Wesley B.; Parthasarathy, Ashwin B.; Busch, David R.; Mesquita, Rickson C.; Greenberg, Joel H.; Yodh, A. G.

2015-03-01

The modified Beer-Lambert law is among the most widely used approaches for analysis of near-infrared spectroscopy (NIRS) reflectance signals for measurements of tissue blood volume and oxygenation. Briefly, the modified Beer-Lambert paradigm is a scheme to derive changes in tissue optical properties based on continuous-wave (CW) diffuse optical intensity measurements. In its simplest form, the scheme relates differential changes in light transmission (in any geometry) to differential changes in tissue absorption. Here we extend this paradigm to the measurement of tissue blood flow by diffuse correlation spectroscopy (DCS). In the new approach, differential changes of the intensity temporal auto-correlation function at a single delay-time are related to differential changes in blood flow. The key theoretical results for measurement of blood flow changes in any tissue geometry are derived, and we demonstrate the new method to monitor cerebral blood flow in a pig under conditions wherein the semi-infinite geometry approximation is fairly good. Specifically, the drug dinitrophenol was injected in the pig to induce a gradual 200% increase in cerebral blood flow, as measured with MRI velocity flow mapping and by DCS. The modified Beer-Lambert law for flow accurately recovered these flow changes using only a single delay-time in the intensity auto-correlation function curve. The scheme offers increased DCS measurement speed of blood flow. Further, the same techniques using the modified Beer-Lambert law to filter out superficial tissue effects in NIRS measurements of deep tissues can be applied to the DCS modified Beer-Lambert law for blood flow monitoring of deep tissues.

Advantageous new conic cannula for spine cement injection.

PubMed

González, Sergio Gómez; Vlad, María Daniela; López, José López; Aguado, Enrique Fernández

2014-09-01

Experimental study to characterize the influence of the cannula geometry on both, the pressure drop and the cement flow velocity established along the cannula. To investigate how the new experimental geometry of cannulas can affect the extravertebral injection pressure and the velocity profiles established along the cannula during the injection process. Vertebroplasty procedure is being used to treat vertebral compression fractures. Vertebra infiltration is favored by the use of suitable: (1) syringes or injector devices; (2) polymer or ceramic bone cements; and (3) cannulas. However, the clinical use of ceramic bone cement has been limited due to press-filtering problems. Thus, new approaches concerning the cannula geometry are needed to minimize the press-filtering of calcium phosphate-based bone cements and thereby broaden its possible applications. Straight, conic, and combined conic-straight new cannulas with different proximal and distal both length and diameter ratios were drawn with computer-assisted design software. The new geometries were theoretically analyzed by: (1) Hagen-Poisseuille law; and (2) computational fluid dynamics. Some experimental models were manufactured and tested for extrusion in order to confirm and further advance the theoretical results. The results confirm that the totally conic cannula model, having proximal to distal diameter ratio equal 2, requires the lowest injection pressure. Furthermore, its velocity profile showed no discontinuity at all along the cannula length, compared with other known combined proximal and distal straight cannulas, where discontinuity was produced at the proximal-distal transition zone. The conclusion is that the conic cannulas: (a) further reduced the extravertebral pressure during the injection process; (b) showed optimum fluid flow velocity profiles to minimize filter-pressing problems, especially when ceramic cements are used; and (c) can be easily manufactured. In this sense, the new conic cannulas should favor the use of calcium phosphate bone cements in the spine. N/A.

Modeling of time-lapse multi-scale seismic monitoring of CO2 injected into a fault zone to enhance the characterization of permeability in enhanced geothermal systems

NASA Astrophysics Data System (ADS)

Zhang, R.; Borgia, A.; Daley, T. M.; Oldenburg, C. M.; Jung, Y.; Lee, K. J.; Doughty, C.; Altundas, B.; Chugunov, N.; Ramakrishnan, T. S.

2017-12-01

Subsurface permeable faults and fracture networks play a critical role for enhanced geothermal systems (EGS) by providing conduits for fluid flow. Characterization of the permeable flow paths before and after stimulation is necessary to evaluate and optimize energy extraction. To provide insight into the feasibility of using CO2 as a contrast agent to enhance fault characterization by seismic methods, we model seismic monitoring of supercritical CO2 (scCO2) injected into a fault. During the CO2 injection, the original brine is replaced by scCO2, which leads to variations in geophysical properties of the formation. To explore the technical feasibility of the approach, we present modeling results for different time-lapse seismic methods including surface seismic, vertical seismic profiling (VSP), and a cross-well survey. We simulate the injection and production of CO2 into a normal fault in a system based on the Brady's geothermal field and model pressure and saturation variations in the fault zone using TOUGH2-ECO2N. The simulation results provide changing fluid properties during the injection, such as saturation and salinity changes, which allow us to estimate corresponding changes in seismic properties of the fault and the formation. We model the response of the system to active seismic monitoring in time-lapse mode using an anisotropic finite difference method with modifications for fracture compliance. Results to date show that even narrow fault and fracture zones filled with CO2 can be better detected using the VSP and cross-well survey geometry, while it would be difficult to image the CO2 plume by using surface seismic methods.

Comparison of two methods for selegiline determination: A flow-injection chemiluminescence method using cadmium sulfide quantum dots and corona discharge ion mobility spectrometry.

PubMed

Khataee, Alireza; Lotfi, Roya; Hasanzadeh, Aliyeh; Iranifam, Mortaza; Zarei, Mahmoud; Joo, Sang Woo

2016-01-15

Two analytical approaches including chemiluminescence (CL) and corona discharge ionization ion mobility spectrometry (CD-IMS) were developed for sensitive determination of selegiline (SG). We found that the CL intensity of the KMnO4-Na2S2O3 CL system was significantly enhanced in the presence of L-cysteine capped CdS quantum dots (QDs). A possible CL mechanism for this CL reaction is proposed. In the presence of SG, the enhanced CL system was inhibited. Based on this inhibition, a simple and sensitive flow-injection CL method was proposed for the determination of SG. Under optimum experimental conditions, the decreased CL intensity was proportional to SG concentration in the range of 0.01 to 30.0 mg L(-1). The detection limit (3σ) was 0.004 mg L(-1). Also, SG was determined using CD-IMS, and under optimum conditions of CD-IMS, calibration curves were linear in the range of 0.15 to 42.0 mg L(-1), with a detection limit (3σ) of 0.03 mg L(-1). The precision of the two methods was calculated by analyzing samples containing 5.0 mg L(-1) of SG (n=11). The relative standard deviations (RSDs%) of the flow-injection CL and CD-IMS methods are 2.17% and 3.83%, respectively. The proposed CL system exhibits a higher sensitivity and precision than the CD-IMS method for the determination of SG. Copyright © 2015. Published by Elsevier B.V.

A simplified computational fluid-dynamic approach to the oxidizer injector design in hybrid rockets

NASA Astrophysics Data System (ADS)

Di Martino, Giuseppe D.; Malgieri, Paolo; Carmicino, Carmine; Savino, Raffaele

2016-12-01

Fuel regression rate in hybrid rockets is non-negligibly affected by the oxidizer injection pattern. In this paper a simplified computational approach developed in an attempt to optimize the oxidizer injector design is discussed. Numerical simulations of the thermo-fluid-dynamic field in a hybrid rocket are carried out, with a commercial solver, to investigate into several injection configurations with the aim of increasing the fuel regression rate and minimizing the consumption unevenness, but still favoring the establishment of flow recirculation at the motor head end, which is generated with an axial nozzle injector and has been demonstrated to promote combustion stability, and both larger efficiency and regression rate. All the computations have been performed on the configuration of a lab-scale hybrid rocket motor available at the propulsion laboratory of the University of Naples with typical operating conditions. After a preliminary comparison between the two baseline limiting cases of an axial subsonic nozzle injector and a uniform injection through the prechamber, a parametric analysis has been carried out by varying the oxidizer jet flow divergence angle, as well as the grain port diameter and the oxidizer mass flux to study the effect of the flow divergence on heat transfer distribution over the fuel surface. Some experimental firing test data are presented, and, under the hypothesis that fuel regression rate and surface heat flux are proportional, the measured fuel consumption axial profiles are compared with the predicted surface heat flux showing fairly good agreement, which allowed validating the employed design approach. Finally an optimized injector design is proposed.

Regimes of Micro-bubble Formation Using Gas Injection into Ladle Shroud

NASA Astrophysics Data System (ADS)

Chang, Sheng; Cao, Xiangkun; Zou, Zongshu

2018-03-01

Gas injection into a ladle shroud is a practical approach to produce micro-bubbles in tundishes, to promote inclusion removal from liquid steel. A semi-empirical model was established to characterize the bubble formation considering the effect of shearing action combined with the non-fully bubble break-up by turbulence. The model shows a good accuracy in predicting the size of bubbles formed in complex flow within the ladle shroud.

Regimes of Micro-bubble Formation Using Gas Injection into Ladle Shroud

NASA Astrophysics Data System (ADS)

Chang, Sheng; Cao, Xiangkun; Zou, Zongshu

2018-06-01

Gas injection into a ladle shroud is a practical approach to produce micro-bubbles in tundishes, to promote inclusion removal from liquid steel. A semi-empirical model was established to characterize the bubble formation considering the effect of shearing action combined with the non-fully bubble break-up by turbulence. The model shows a good accuracy in predicting the size of bubbles formed in complex flow within the ladle shroud.

Field demonstration of foam injection to confine a chlorinated solvent source zone.

PubMed

Portois, Clément; Essouayed, Elyess; Annable, Michael D; Guiserix, Nathalie; Joubert, Antoine; Atteia, Olivier

2018-05-01

A novel approach using foam to manage hazardous waste was successfully demonstrated under active site conditions. The purpose of the foam was to divert groundwater flow, that would normally enter the source zone area, to reduce dissolved contaminant release to the aquifer. During the demonstration, foam was pre generated and directly injected surrounding the chlorinated solvent source zone. Despite the constraints related to the industrial activities and non-optimal position of the injection points, the applicability and effectiveness of the approach have been highlighted using multiple metrics. A combination of measurements and modelling allowed definition of the foam extent surrounding each injection point, and this appears to be the critical metric to define the success of the foam injection approach. Information on the transport of chlorinated solvents in groundwater showed a decrease of contaminant flux by a factor of 4.4 downstream of the confined area. The effective permeability reduction was maintained over a period of three months. The successful containment provides evidence for consideration of the use of foam to improve traditional flushing techniques, by increasing the targeting of contaminants by remedial agents. Copyright © 2018 Elsevier B.V. All rights reserved.

97% accuracy of intra-articular glenohumeral injection with a modified (Delaware) posterior bone touch technique.

PubMed

Axe, Jeremie M; Axe, Michael J

2013-10-01

Unguided approaches have not demonstrated evidence of highly accurate intra-articular glenohumeral injections. The purpose of this study was to assess the accuracy of a posterior approach bone touch technique in conscious subjects without shoulder pathology as a first step in developing an accurate, reliable technique for use in patients. Twenty-six young subjects (age 22-26) without shoulder pathology (BMI 24 +/- 3), had bilateral shoulders injected while awake and seated. A 20 gauge 3.5-inch needle was introduced 1.5 cm below the scapular spine mid-way between the posterior lateral acromial corner and the posterior axillary crease. In Trial I, 20 shoulders were injected. After touching the humerus, the arm was oscillated. The needle advanced to 4-5 cm and 10 mL of dye injected. Pop and ease of flow were recorded. Immediate room change, spot fluoroscopy, and independent experienced radiology reading followed. In Trial II, 32 shoulders were injected. The technique was modified to touching the humerus, externally rotating the arm 25 degrees, and while remaining in bone contact, delivering 10 mL of dye. The same data as Trial I was recorded. In Trial I, 14/20 (70 percent) had dye within the glenohumeral joint. Five of seven failures were too anterior showing dye around the subscapularis muscle and all were associated with a pop. In Trial II, 31/32 (97 percent) had dye within glenohumeral joint. Twenty-three of 32 (72 percent) had a "pop," including the failure. Overall, 45/52 (87 percent) had dye within glenohumeral joint. Thirty-one of 52 (71 percent) of all shoulders had a "pop." Twenty-three of 52 (44 percent) shoulders had pain, resolving within 24 hours. A modified (Delaware) posterior bone touch technique for glenohumeral joint injection is 97 percent accurate in conscious healthy young subjects. Pop and ease of flow are not always indicative of correct needle placement. This study serves as an important first step in determining an optimum approach for injecting pathologic glenohumeral joints with corticosteroids or hyaluronic acid. IV Case Series.

A Computational Model of Coupled Multiphase Flow and Geomechanics to Study Fault Slip and Induced Seismicity

NASA Astrophysics Data System (ADS)

Juanes, R.; Jha, B.

2014-12-01

The coupling between subsurface flow and geomechanical deformation is critical in the assessment of the environmental impacts of groundwater use, underground liquid waste disposal, geologic storage of carbon dioxide, and exploitation of shale gas reserves. In particular, seismicity induced by fluid injection and withdrawal has emerged as a central element of the scientific discussion around subsurface technologies that tap into water and energy resources. Here we present a new computational approach to model coupled multiphase flow and geomechanics of faulted reservoirs. We represent faults as surfaces embedded in a three-dimensional medium by using zero-thickness interface elements to accurately model fault slip under dynamically evolving fluid pressure and fault strength. We incorporate the effect of fluid pressures from multiphase flow in the mechanical stability of faults and employ a rigorous formulation of nonlinear multiphase geomechanics that is capable of handling strong capillary effects. We develop a numerical simulation tool by coupling a multiphase flow simulator with a mechanics simulator, using the unconditionally stable fixed-stress scheme for the sequential solution of two-way coupling between flow and geomechanics. We validate our modeling approach using several synthetic, but realistic, test cases that illustrate the onset and evolution of earthquakes from fluid injection and withdrawal. We also present the application of the coupled flow-geomechanics simulation technology to the post mortem analysis of the Mw=5.1, May 2011 Lorca earthquake in south-east Spain, and assess the potential that the earthquake was induced by groundwater extraction.

Coupled Mechanical and Thermal Modeling of Frictional Melt Injection to Constrain Physical Conditions of the Earthquake Source Region

NASA Astrophysics Data System (ADS)

Sawyer, W.; Resor, P. G.

2016-12-01

Pseudotachylyte, a fault rock formed through coseismic frictional melting, provides an important record of coseismic mechanics. In particular, injection veins formed at a high angle to the fault surface have been used to estimate rupture directivity, velocity, pulse length, stress and strength drop, as well as slip weakening distance and wall rock stiffness. These studies, however, have generally treated injection vein formation as a purely elastic process and have assumed that processes of melt generation, transport, and solidification have little influence on the final vein geometry. Using a modified analytical approximation of injection vein formation based on a dike intrusion model we find that the timescales of quenching and flow propagation are similar for a composite set of injection veins compiled from the Asbestos Mountain Fault, USA (Rowe et al., 2012), Gole Larghe Fault Zone, Italy (Griffith et al., 2012) and the Fort Foster Brittle Zone. This indicates a complex, dynamic process whose behavior is not fully captured by the current approach. To assess the applicability of the simplifying assumptions of the dike model when applied to injection veins we employ a finite-element time-dependent model of injection vein formation. This model couples elastic deformation of the wall rock with the fluid dynamics and heat transfer of the frictional melt. The final geometry of many injection veins is unaffected by the inclusion of these processes. However, some injection veins are found to be flow limited, with a final geometry reflecting cooling of the vein before it reaches an elastic equilibrium with the wall rock. In these cases, numerical results are significantly different from the dike model, and two basic assumptions of the dike model, self-similar growth and a uniform pressure gradient, are shown to be false. Additionally, we apply the finite-element model to provide two new constraints on the Fort Foster coseismic environment: a lower limit on the initial melt temperature of 1400 *C, and either significant coseismic wall rock softening or high transient tensile stress.

Modeling CO2 distribution in a heterogeneous sandstone reservoir: the Johansen Formation, northern North Sea

NASA Astrophysics Data System (ADS)

Sundal, Anja; Miri, Rohaldin; Petter Nystuen, Johan; Dypvik, Henning; Aagaard, Per

2013-04-01

The last few years there has been broad attention towards finding permanent storage options for CO2. The Norwegian continental margin holds great potential for storage in saline aquifers. Common for many of these reservoir candidates, however, is that geological data are sparse relative to thoroughly mapped hydrocarbon reservoirs in the region. Scenario modeling provides a method for estimating reservoir performances for potential CO2 storage sites and for testing injection strategies. This approach is particularly useful in the evaluation of uncertainties related to reservoir properties and geometry. In this study we have tested the effect of geological heterogeneities in the Johansen Formation, which is a laterally extensive sandstone and saline aquifer at burial depths of 2 - 4 km, proposed as a suitable candidate for CO2 storage by Norwegian authorities. The central parts of the Johansen Formation are underlying the operating hydrocarbon field Troll. In order not to interfere with ongoing gas production, a potential CO2 injection well should be located at a safe distance from the gas reservoir, which consequently implies areas presently without well control. From 3D seismic data, prediction of spatial extent of sandstone is possible to a certain degree, whereas intra-reservoir flow baffles such as draping mudstone beds and calcite cemented layers are below seismic resolution. The number and lateral extent of flow baffles, as well as porosity- and permeability distributions are dependent of sedimentary facies and diagenesis. The interpretation of depositional environment and burial history is thus of crucial importance. A suite of scenario models was established for a potential injection area south of the Troll field. The model grids where made in Petrel based on our interpretations of seismic data, wire line logs, core and cuttings samples. Using Eclipse 300 the distribution of CO2 is modeled for different geological settings; with and without the presence of pervasive low permeability draping mudstone layers, and with varying lateral extent of potential calcite cemented layers in 8 to 15 intra-reservoir depth levels. The modeled area covers 10 x 15.8 km, with a thickness of 110 m at the injection point. Simulations were run with an injection phase of 30 years plus 100 years of migration. The presence of meso-scale flow baffles causes a reduction in vertical permeability in addition to the facies related variation on the micro-scale. Scenarios including potential flow baffles as separate layers in the model grids were compared to scenarios in which the effect of flow baffles were included using harmonic mean average of vertical permeability. The subsequent differences in CO2 distribution are important in estimating the contact area between the plume front and reservoir brine. A heterogeneous reservoir with internal flow baffles is not necessarily a disadvantage as long as sufficient injectivity is maintained within individual sandstone bodies. In each scenario we aim to adapt a suitable injection strategy with respect to utilizing local effects such as the delimitation of gravitational flow, in order to increase reservoir sweep and maximize the effect of trapping mechanisms (i.e. residual, stratigraphic, mineral and dissolution).

A Multi-scale Approach for CO2 Accounting and Risk Analysis in CO2 Enhanced Oil Recovery Sites

NASA Astrophysics Data System (ADS)

Dai, Z.; Viswanathan, H. S.; Middleton, R. S.; Pan, F.; Ampomah, W.; Yang, C.; Jia, W.; Lee, S. Y.; McPherson, B. J. O. L.; Grigg, R.; White, M. D.

2015-12-01

Using carbon dioxide in enhanced oil recovery (CO2-EOR) is a promising technology for emissions management because CO2-EOR can dramatically reduce carbon sequestration costs in the absence of greenhouse gas emissions policies that include incentives for carbon capture and storage. This study develops a multi-scale approach to perform CO2 accounting and risk analysis for understanding CO2 storage potential within an EOR environment at the Farnsworth Unit of the Anadarko Basin in northern Texas. A set of geostatistical-based Monte Carlo simulations of CO2-oil-water flow and transport in the Marrow formation are conducted for global sensitivity and statistical analysis of the major risk metrics: CO2 injection rate, CO2 first breakthrough time, CO2 production rate, cumulative net CO2 storage, cumulative oil and CH4 production, and water injection and production rates. A global sensitivity analysis indicates that reservoir permeability, porosity, and thickness are the major intrinsic reservoir parameters that control net CO2 injection/storage and oil/CH4 recovery rates. The well spacing (the distance between the injection and production wells) and the sequence of alternating CO2 and water injection are the major operational parameters for designing an effective five-spot CO2-EOR pattern. The response surface analysis shows that net CO2 injection rate increases with the increasing reservoir thickness, permeability, and porosity. The oil/CH4 production rates are positively correlated to reservoir permeability, porosity and thickness, but negatively correlated to the initial water saturation. The mean and confidence intervals are estimated for quantifying the uncertainty ranges of the risk metrics. The results from this study provide useful insights for understanding the CO2 storage potential and the corresponding risks of commercial-scale CO2-EOR fields.

Distribution of injected power fluctuations in electroconvection.

PubMed

Tóth-Katona, Tibor; Gleeson, J T

2003-12-31

We report on the distribution spectra of the fluctations in the amount of power injected into a liquid crystal undergoing electroconvective flow. The probability distribution functions (PDFs) of the fluc-tuations as well as the magnitude of the fluctuations have been determined in a wide range of imposed stress both for unconfined and confined flow geometries. These spectra are compared to those found in other systems held far from equilibrium, and find that in certain conditions we obtain the universal PDF form reported by Phys. Rev. Lett. 84, 3744 (2000)]. Moreover, the PDF approaches this universal form via an interesting mechanism whereby the distribution's negative tail evolves towards form in a different manner than the positive tail.

Coupled Multi-physics analysis of Caprock Integrity and Fault Reactivation during CO2 Sequestration*

NASA Astrophysics Data System (ADS)

Newell, P.; Martinez, M. J.; Bishop, J.

2012-12-01

Structural/stratigraphic trapping beneath a low-permeable caprock layer is the primary trapping mechanism for long-term subsurface sequestration of CO2. Pre-existing fracture networks, injection induced fractures, and faults are of concern for possible CO2 leakage both during and after injection. In this work we model the effects of both caprock jointing and a fault on the caprock sealing integrity during various injection scenarios. The modeling effort uses a three-dimensional finite-element based coupled multiphase flow and geomechanics simulator. The joints within the caprock are idealized as equally spaced and parallel. Both the mechanical and flow behavior of the joint network are treated within an effective continuum formulation. The mechanical behavior of the joint network is linear elastic in shear and nonlinear elastic in the normal direction. The flow behavior of the joint network is treated using the classical cubic-law relating flow rate and aperture. The flow behavior is then upscaled to obtain an effective permeability. The fault is modeled as a finite-thickness layer with multiple joint sets. The joint sets within the fault region are modeled following the same mechanical and flow formulation as the joints within the caprock. Various injection schedules as well as fault and caprock jointing configurations within a proto-typical sequestration site have been investigated. The resulting leakage rates through the caprock and fault are compared to those assuming intact material. The predicted leakage rates are a strong nonlinear function of the injection rate. *This material is based upon work supported as part of the Center for Frontiers of Subsurface Energy Security, an Energy Frontier Research Center funded by the U.S. Department of Energy, Office of Science, Office of Basic Energy Sciences under Award Number DE-SC0001114. Sandia is a multi-program laboratory operated by Sandia Corporation, a Lockheed Martin Company, for the United States Department of Energys National Nuclear Security Administration under Contract DE-AC04-94AL85000.

Pre-Test CFD for the Design and Execution of the Enhanced Injection and Mixing Project at NASA Langley Research Center

NASA Technical Reports Server (NTRS)

Drozda, Tomasz G.; Axdahl, Erik L.; Cabell, Karen F.

2014-01-01

With the increasing costs of physics experiments and simultaneous increase in availability and maturity of computational tools it is not surprising that computational fluid dynamics (CFD) is playing an increasingly important role, not only in post-test investigations, but also in the early stages of experimental planning. This paper describes a CFD-based effort executed in close collaboration between computational fluid dynamicists and experimentalists to develop a virtual experiment during the early planning stages of the Enhanced Injection and Mixing project at NASA Langley Research Center. This projects aims to investigate supersonic combustion ramjet (scramjet) fuel injection and mixing physics, improve the understanding of underlying physical processes, and develop enhancement strategies and functional relationships relevant to flight Mach numbers greater than 8. The purpose of the virtual experiment was to provide flow field data to aid in the design of the experimental apparatus and the in-stream rake probes, to verify the nonintrusive measurements based on NO-PLIF, and to perform pre-test analysis of quantities obtainable from the experiment and CFD. The approach also allowed for the joint team to develop common data processing and analysis tools, and to test research ideas. The virtual experiment consisted of a series of Reynolds-averaged simulations (RAS). These simulations included the facility nozzle, the experimental apparatus with a baseline strut injector, and the test cabin. Pure helium and helium-air mixtures were used to determine the efficacy of different inert gases to model hydrogen injection. The results of the simulations were analyzed by computing mixing efficiency, total pressure recovery, and stream thrust potential. As the experimental effort progresses, the simulation results will be compared with the experimental data to calibrate the modeling constants present in the CFD and validate simulation fidelity. CFD will also be used to investigate different injector concepts, improve understanding of the flow structure and flow physics, and develop functional relationships. Both RAS and large eddy simulations (LES) are planned for post-test analysis of the experimental data.

3D-printed and CNC milled flow-cells for chemiluminescence detection.

PubMed

Spilstead, Kara B; Learey, Jessica J; Doeven, Egan H; Barbante, Gregory J; Mohr, Stephan; Barnett, Neil W; Terry, Jessica M; Hall, Robynne M; Francis, Paul S

2014-08-01

Herein we explore modern fabrication techniques for the development of chemiluminescence detection flow-cells with features not attainable using the traditional coiled tubing approach. This includes the first 3D-printed chemiluminescence flow-cells, and a milled flow-cell designed to split the analyte stream into two separate detection zones within the same polymer chip. The flow-cells are compared to conventional detection systems using flow injection analysis (FIA) and high performance liquid chromatography (HPLC), with the fast chemiluminescence reactions of an acidic potassium permanganate reagent with morphine and a series of adrenergic phenolic amines. Copyright © 2014 Elsevier B.V. All rights reserved.

Linking Chaotic Advection with Subsurface Biogeochemical Processes

NASA Astrophysics Data System (ADS)

Mays, D. C.; Freedman, V. L.; White, S. K.; Fang, Y.; Neupauer, R.

2017-12-01

This work investigates the extent to which groundwater flow kinematics drive subsurface biogeochemical processes. In terms of groundwater flow kinematics, we consider chaotic advection, whose essential ingredient is stretching and folding of plumes. Chaotic advection is appealing within the context of groundwater remediation because it has been shown to optimize plume spreading in the laminar flows characteristic of aquifers. In terms of subsurface biogeochemical processes, we consider an existing model for microbially-mediated reduction of relatively mobile uranium(VI) to relatively immobile uranium(IV) following injection of acetate into a floodplain aquifer beneath a former uranium mill in Rifle, Colorado. This model has been implemented in the reactive transport code eSTOMP, the massively parallel version of STOMP (Subsurface Transport Over Multiple Phases). This presentation will report preliminary numerical simulations in which the hydraulic boundary conditions in the eSTOMP model are manipulated to simulate chaotic advection resulting from engineered injection and extraction of water through a manifold of wells surrounding the plume of injected acetate. This approach provides an avenue to simulate the impact of chaotic advection within the existing framework of the eSTOMP code.

Bubble Generation in a Flowing Liquid Medium and Resulting Two-Phase Flow in Microgravity

NASA Technical Reports Server (NTRS)

Pais, S. C.; Kamotani, Y.; Bhunia, A.; Ostrach, S.

1999-01-01

The present investigation reports a study of bubble generation under reduced gravity conditions, using both a co-flow and a cross-flow configuration. This study may be used in the conceptual design of a space-based thermal management system. Ensuing two-phase flow void fraction can be accurately monitored using a single nozzle gas injection system within a continuous liquid flow conduit, as utilized in the present investigation. Accurate monitoring of void fraction leads to precise control of heat and mass transfer coefficients related to a thermal management system; hence providing an efficient and highly effective means of removing heat aboard spacecraft or space stations. Our experiments are performed in parabolic flight aboard the modified DC-9 Reduced Gravity Research Aircraft at NASA Lewis Research Center, using an air-water system. For the purpose of bubble dispersion in a flowing liquid, we use both a co-flow and a cross-flow configuration. In the co-flow geometry, air is introduced through a nozzle in the same direction with the liquid flow. On the other hand, in the cross-flow configuration, air is injected perpendicular to the direction of water flow, via a nozzle protruding inside the two-phase flow conduit. Three different flow conduit (pipe) diameters are used, namely, 1.27 cm, 1.9 cm and 2.54 cm. Two different ratios of nozzle to pipe diameter (D(sub N))sup * are considered, namely (D(sub N))sup * = 0.1 and 0.2, while superficial liquid velocities are varied from 8 to 70 cm/s depending on flow conduit diameter. It is experimentally observed that by holding all other flow conditions and geometry constant, generated bubbles decrease in size with increase in superficial liquid velocity. Detached bubble diameter is shown to increase with air injection nozzle diameter. Likewise, generated bubbles grow in size with increasing pipe diameter. Along the same lines, it is shown that bubble frequency of formation increases and hence the time to detachment of a forming bubble decreases, as the superficial liquid velocity is in-creased. Furthermore, it is shown that the void fraction of the resulting two-phase flow increases with volumetric gas flow rate Q(sub d), pipe diameter and gas injection nozzle diameter, while they decrease with surrounding liquid flow. The important role played by flowing liquid in detaching bubbles in a reduced gravity environment is thus emphasized. We observe that the void fraction can be accurately controlled by using single nozzle gas injection, rather than by employing multiple port injection, since the later system gives rise to unpredictable coalescence of adjacent bubbles. It is of interest to note that empirical bubble size and corresponding void fraction are somewhat smaller for the co-flow geometry than the cross-flow configuration at similar flow conditions with similar pipe and nozzle diameters. In order to supplement the empirical data, a theoretical model is employed to study single bubble generation in the dynamic (Q(sub d) = 1 - 1000 cu cm/s) and bubbly flow regime within the framework of the co-flow configuration. This theoretical model is based on an overall force balance acting on the bubble during the two stages of generation, namely the expansion and the detachment stage. Two sets of forces, one aiding and the other inhibiting bubble detachment are identified. Under conditions of reduced gravity, gas momentum flux enhances, while the surface tension force at the air injection nozzle tip inhibits bubble detachment. In parallel, liquid drag and inertia can act as both attaching and detaching forces, depending on the relative velocity of the bubble with respect to the surrounding liquid. Predictions of the theoretical model compare well with our experimental results. However, at higher superficial liquid velocities, as the bubble loses its spherical form, empirical bubble size no longer matches the theoretical predictions. In summary, we have developed a combined experimental and theoretical work, which describes the complex process of bubble generation and resulting two-phase flow in a microgravity environment. Results of the present study can be used in a wide range of space-based applications, such as thermal energy and power generation, propulsion, cryogenic storage and long duration life support systems, necessary for programs such as NASA's Human Exploration for the Development of Space (HEDS).

Delineating Fecal Contaminant Sources and Travel Times in a Karst Groundwater Basin, Inner Bluegrass Region, Kentucky

NASA Astrophysics Data System (ADS)

Ward, J. W.; Reed, T. M.; Fryar, A. E.; Brion, G. M.

2006-12-01

Because of preferential flowpaths via features such as sinkholes and conduits, karst aquifers are susceptible to non-point-source pollution from agricultural and urban drainage. With many karst aquifers being drinking- water sources, pathogens are contaminants of public health concern. Monitoring of microbial parameters (total coliforms [TC], atypical colonies [AC] and fecal coliform bacteria [FC]) transpired biweekly from December 2002 March 2004 and weekly from February October 2005 at Blue Hole Spring, which drains outlying farm lands and the town of Versailles in the Inner Bluegrass Region of Kentucky. Physicochemical parameters (discharge, temperature, specific conductance, and pH) were measured continuously during the entire period. The AC/TC ratio, which had been employed only in surface water-quality studies, was used with FC counts, precipitation and discharge data to determine sources of fecal loading to ground water as result of land-use practices. An AC/TC ratio < 10 demonstrates fresh input of fecal matter, while a larger ratio can represent a variety of occurrences, including aged fecal material input and/or lack of nutrient input into the system. AC/TC ratio data in the 2002 04 dataset behaved similarly to surface waters, with ratios > 10 during dry periods and < 10 during wet periods, while the 2005 data demonstrated a very irregular pattern. The difference in these two data sets indicated a compositional change within the groundwater basin between the two sampling periods, perhaps as a result of construction at a sewage treatment plant adjoining the spring. Solute (rhodamine WT fluorescent dye and bromide) and particle (1-μm diameter fluorescent latex microspheres) tracer tests were conducted during summer 2006 to examine contaminant mobility within the system under base-flow and storm-flow conditions. Rainfall was limited prior to the base-flow trace, totaling 0.025 cm within 2 weeks prior to the slug injection. Base-flow discharge averaged 400 m3/s and solute breakthrough began ~ 7.5 hours post injection and cleared the system after 77 hours. For the storm-flow trace, rainfall totaled 3.12 cm prior to injection, with another 9.35 cm of rainfall occurring over the two week monitoring period. Spring discharge during the storm-flow trace averaged 0.443 m3/s, with a maximum of 0.503 m3/s. Under storm-flow conditions solute breakthrough began ~ 2.33 hours post injection, with particle breakthrough beginning ~ 2.5 hours post injection. Bromide concentrations at the spring were < 0.1 ppm (the detection limit, or DL) 5.5 hours after injection, while rhodamine WT concentrations were < DL (0.1 ppb) 14 hours post injection. Microspheres were detected at the spring until 164 hours after injection. These traces demonstrate that storms in this karst basin can accelerate solute movement, and particles can remain mobile for as long as 1 week after introduction.

Subwavelength prestressed microcantilevers based metamaterials for efficient manipulation of terahertz waves

DTIC Science & Technology

2015-07-01

for the fluid flow controlled MEMS metamaterial with PDMS chamber. (b)-(d) shows the cantilever deformation with respect to increasing fluid flow...Firstly the metamaterial was integrated with a polydimethylsiloxane fluidic channel and the injection flow rate was varied from 0 to 5 ml/min

Effects of Wall-Normal and Angular Momentum Injections in Airfoil Separation Control

NASA Astrophysics Data System (ADS)

Munday, Phillip M.; Taira, Kunihiko

2018-05-01

The objective of this computational study is to quantify the influence of wall-normal and angular momentum injections in suppressing laminar flow separation over a canonical airfoil. Open-loop control of fully separated, incompressible flow over a NACA 0012 airfoil at $\\alpha = 9^\\circ$ and $Re = 23,000$ is examined with large-eddy simulations. This study independently introduces wall-normal momentum and angular momentum into the separated flow using swirling jets through model boundary conditions. The response of the flow field and the surface vorticity fluxes to various combinations of actuation inputs are examined in detail. It is observed that the addition of angular momentum input to wall-normal momentum injection enhances the suppression of flow separation. Lift enhancement and suppression of separation with the wall-normal and angular momentum inputs are characterized by modifying the standard definition of the coefficient of momentum. The effect of angular momentum is incorporated into the modified coefficient of momentum by introducing a characteristic swirling jet velocity based on the non-dimensional swirl number. With this single modified coefficient of momentum, we are able to categorize each controlled flow into separated, transitional, and attached flows.

Satellite-based measurements of surface deformation reveal fluid flow associated with the geological storage of carbon dioxide

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vasco, D.W.; Rucci, A.; Ferretti, A.

2009-10-15

Interferometric Synthetic Aperture Radar (InSAR), gathered over the In Salah CO{sub 2} storage project in Algeria, provides an early indication that satellite-based geodetic methods can be effective in monitoring the geological storage of carbon dioxide. An injected volume of 3 million tons of carbon dioxide, from one of the first large-scale carbon sequestration efforts, produces a measurable surface displacement of approximately 5 mm/year. Using geophysical inverse techniques we are able to infer flow within the reservoir layer and within a seismically detected fracture/ fault zone intersecting the reservoir. We find that, if we use the best available elastic Earth model,more » the fluid flow need only occur in the vicinity of the reservoir layer. However, flow associated with the injection of the carbon dioxide does appear to extend several kilometers laterally within the reservoir, following the fracture/fault zone.« less

Mathematical modeling of the in-mold coating process for injection-molded thermoplastic parts

NASA Astrophysics Data System (ADS)

Chen, Xu

In-Mold Coating (IMC) has been successfully used for many years for exterior body panels made from compression molded Sheet Molding Compound (SMC). The coating material is a single component reactive fluid, designed to improve the surface quality of SMC moldings in terms of functional and cosmetic properties. When injected onto a cured SMC part, IMC cures and bonds to provide a pain-like surface. Because of its distinct advantages, IMC is being considered for application to injection molded thermoplastic parts. For a successful in mold coating operation, there are two key issues related to the flow of the coating. First, the injection nozzle should be located such that the thermoplastic substrate is totally covered and the potential for air trapping is minimized. The selected location should be cosmetically acceptable since it most likely will leave a mark on the coated surface. The nozzle location also needs to be accessible for easy of maintenance. Secondly, the hydraulic force generated by the coating injection pressure should not exceed the available clamping tonnage. If the clamping force is exceeded, coating leakage will occur. In this study, mathematical models for IMC flow on the compressible thermoplastic substrate have been developed. Finite Difference Method (FDM) is first used to solve the 1 dimensional (1D) IMC flow problem. In order to investigate the application of Control Volume based Finite Element Method (CV/FEM) to more complicated two dimensional IMC flow, that method is first evaluated by solving the 1D IMC flow problem. An analytical solution, which can be obtained when a linear relationship between the coating thickness and coating injection pressure is assumed, is used to verify the numerical results. The mathematical models for the 2 dimensional (2D) IMC flow are based on the generalized Hele-Shaw approximation. It has been found experimentally that the power law viscosity model adequately predicts the rheological behavior of the coating. The compressibility of the substrate is modeled by the 2-domain Tait PVT equation. CV/FEM is used to solve the discretized governing equations. A computer code has been developed to predict the fill pattern of the coating and the injection pressure. A number of experiments have been conducted to verify the numerical predictions of the computer code. It has been found both numerically and experimentally that the substrate thickness plays a significant role on the IMC fill pattern.

A line source tracer test - a better method for assessing high groundwater velocity

NASA Astrophysics Data System (ADS)

Magal, E.; Weisbrod, N.; Yakirevich, A.; Kurtzman, D.; Yechieli, Y.

2009-12-01

A line source injection is suggested as an effective method for assessing groundwater velocities and flow directions in subsurface characterized by high water fluxes. Modifying the common techniques of injecting a tracer into a well was necessary after frequently-used methods of natural and forced gradient tracer tests ended with no reliable information on the local groundwater flow. In a field experiment, tracers were injected into 8-m long line injection system constructed below the water table almost perpendicular to the assumed flow direction. The injection system was divided to four separate segments (each 2 m long) enabling the injection of four different tracers along the line source. An array of five boreholes located in an area of 10x10 m downstream was used for monitoring the tracers' transport. Two dye tracers (Uranine and Na Naphthionate) were injected in a long pulse of several hours into two of the injection pipe segments and two tracers (Rhenium oxide and Gd-DTPA) were instantaneously injected to the other two segments. The tracers were detected 0.7 to 2.3 hours after injection in four of the five observation wells, located 2.3 to 10 m from the injection system, respectively. Groundwater velocities were calculated directly from the tracers' arrival times and by fitting the observed breakthrough curves to simulations with one and two dimensions analytical solutions for conservative tracer transport. The groundwater velocity was determined to be ~100 m/d. The longitudinal dispersivity value, generated from fitting the tracer breakthrough curves, was in a range of 0.2-3m. The groundwater flow direction was derived based on the arrival of the tracers and was found to be consistent with the apparent direction of the hydraulic gradient. The hydraulic conductivity derived from the groundwater velocity was ~1200 m/d, which is in the upper range of gravel sediment.

Aquifer-test data and borehole flow test results from monitoring well 16P52 at the South Trend development area number 1, McKinley County, New Mexico

USGS Publications Warehouse

Stevens, Ken

1984-01-01

Mobil Oil Corporation personnel have designated at least four sandstone intervals, A-D (top to bottom), on the single-point resistivity logs of wells drilled in the South Trend Development Area. This report presents time-drawdown data reported by Mobil Oil Corporation from singly (A or B or C or D sandstone interval) and multiply (A, B, C, and D sandstone Intervals) completed wells for the August 16-17, 1982 aquifer test at the South Trend Development Area Site 1. This report also describes the results of flowmeter and brine-injection tests by the U.S. Geological Survey in monitoring well 16P52. Well 16P52 is open to sandstone intervals A, B, C, and D. On July 26, 1982, water was injected at a rate of 1.43 cubic feet per minute above the A sandstone interval in well 16P52. Based on flowmeter data, the calculated rates of flow were 1.23 cubic feet per minute between the A and B sandstone intervals, 0.63 cubic foot per minute between the B and C sandstone intervals, and less than 0.17 cubic foot per minute between the C and D sandstone intervals. Based upon brine-slug-injection tests conducted during August 1982, the calculated flow rates between sandstone intervals A and B are as follows: 0.01 cubic foot per minute upward flow (B to A) about 5 hours after pumping began for the aquifer test; 0.004 cubic foot per minute upward flow (B to A) about 21 hours after pumping began; and 0.0 cubic foot per minute about 46 hours after the pump was turned off. All other brine-slug-injection tests measured no flow.

A rapid, automated approach to optimisation of multiple reaction monitoring conditions for quantitative bioanalytical mass spectrometry.

PubMed

Higton, D M

2001-01-01

An improvement to the procedure for the rapid optimisation of mass spectrometry (PROMS), for the development of multiple reaction methods (MRM) for quantitative bioanalytical liquid chromatography/tandem mass spectrometry (LC/MS/MS), is presented. PROMS is an automated protocol that uses flow-injection analysis (FIA) and AppleScripts to create methods and acquire the data for optimisation. The protocol determines the optimum orifice potential, the MRM conditions for each compound, and finally creates the MRM methods needed for sample analysis. The sensitivities of the MRM methods created by PROMS approach those created manually. MRM method development using PROMS currently takes less than three minutes per compound compared to at least fifteen minutes manually. To further enhance throughput, approaches to MRM optimisation using one injection per compound, two injections per pool of five compounds and one injection per pool of five compounds have been investigated. No significant difference in the optimised instrumental parameters for MRM methods were found between the original PROMS approach and these new methods, which are up to ten times faster. The time taken for an AppleScript to determine the optimum conditions and build the MRM methods is the same with all approaches. Copyright 2001 John Wiley & Sons, Ltd.

Experimental Investigation of Diffuser Hub Injection to Improve Centrifugal Compressor Stability

NASA Technical Reports Server (NTRS)

Skoch, Gary J.

2004-01-01

Results from a series of experiments to investigate whether centrifugal compressor stability could be improved by injecting air through the diffuser hub surface are reported. The research was conducted in a 4:1 pressure ratio centrifugal compressor configured with a vane-island diffuser. Injector nozzles were located just upstream of the leading edge of the diffuser vanes. Nozzle orientations were set to produce injected streams angled at 8, 0 and +8 degrees relative to the vane mean camber line. Several injection flow rates were tested using both an external air supply and recirculation from the diffuser exit. Compressor flow range did not improve at any injection flow rate that was tested. Compressor flow range did improve slightly at zero injection due to the flow resistance created by injector openings on the hub surface. Leading edge loading and semi-vaneless space diffusion showed trends similar to those reported earlier from shroud surface experiments that did improve compressor flow range. Opposite trends are seen for hub injection cases where compressor flow range decreased. The hub injection data further explain the range improvement provided by shroud-side injection and suggest that different hub-side techniques may produce range improvement in centrifugal compressors.

Influence of G-jitter on the characteristics of a non-premixed flame: Experimental approach

NASA Astrophysics Data System (ADS)

Joulain, Pierre; Cordeiro, Pierre; Rouvreau, Sébastien; Legros, Guillaume; Fuentes, Andres; Torero, José L.

2005-03-01

The combustion of a flat plate in a boundary layer under microgravity conditions, which was first described by Emmons, is studied using a gas burner. Magnitude of injection and blowing velocities are chosen to be characteristic of pyrolyzing velocity of solid fuels, and of ventilation systems in space stations. These velocities are about 0.1 m/s for oxidiser flow and 0.004m/s for fuel flow. In this configuration, flame layout results from a coupled interaction between oxidiser flow, fuel flow and thermal expansion. Influences of these parameters are studied experimentally by means of flame length and standoff distance measurements using CH* chemiluminescence's and visible emission of the flame. Flow was also studied with Particle Image Velocimetry (PIV). Inert flows, with and without injection, and reacting flow in a microgravity environment were considered to distinguish aerodynamic from thermal effect. Thermal expansion effects have been shown by means of the acceleration of oxidiser flow. Three-dimensional effects, which are strongly marked for high injection velocities were studied. Three-dimensional tools adaptability to parabolic flights particular conditions were of concern. Flame sensitivity to g-jitters was investigated according to g-jitters frequency and range involved by parabolic flights. It appears that flame location (standoff distance), flame characteristics (length, thickness, brightness) and the aerodynamic field of the low velocity reacting flow are very much affected by the fluctuation of the gravity level or g-jitter. The lower the g-jitter frequency is, the higher the perturbation. Consequently it is difficult to perform relevant experiments for a main flow velocity lower than 0.05m/s. DNS calculations confirm the present observations, but most of the results are presented elsewhere.

Assessment of key transport parameters in a karst system under different dynamic conditions based on tracer experiments: the Jeita karst system, Lebanon

NASA Astrophysics Data System (ADS)

Doummar, Joanna; Margane, Armin; Geyer, Tobias; Sauter, Martin

2018-03-01

Artificial tracer experiments were conducted in the mature karst system of Jeita (Lebanon) under various flow conditions using surface and subsurface tracer injection points, to determine the variation of transport parameters (attenuation of peak concentration, velocity, transit times, dispersivity, and proportion of immobile and mobile regions) along fast and slow flow pathways. Tracer breakthrough curves (TBCs) observed at the karst spring were interpreted using a two-region nonequilibrium approach (2RNEM) to account for the skewness in the TBCs' long tailings. The conduit test results revealed a discharge threshold in the system dynamics, beyond which the transport parameters vary significantly. The polynomial relationship between transport velocity and discharge can be related to the variation of the conduit's cross-sectional area. Longitudinal dispersivity in the conduit system is not a constant value (α = 7-10 m) and decreases linearly with increasing flow rate because of dilution effects. Additionally, the proportion of immobile regions (arising from conduit irregularities) increases with decreasing water level in the conduit system. From tracer tests with injection at the surface, longitudinal dispersivity values are found to be large (8-27 m). The tailing observed in some TBCs is generated in the unsaturated zone before the tracer actually arrives at the major subsurface conduit draining the system. This work allows the estimation and prediction of the key transport parameters in karst aquifers. It shows that these parameters vary with time and flow dynamics, and they reflect the geometry of the flow pathway and the origin of infiltrating (potentially contaminated) recharge.

Characterization of electrokinetic gating valve in microfluidic channels.

PubMed

Zhang, Guiseng; Du, Wei; Liu, Bi-Feng; Hisamoto, Hideaki; Terabe, Shigeru

2007-02-12

Electrokinetic gating, functioning as a micro-valve, has been widely employed in microfluidic chips for sample injection and flow switch. Investigating its valving performance is fundamentally vital for microfluidics and microfluidics-based chemical analysis. In this paper, electrokinetic gating valve in microchannels was evaluated using optical imaging technique. Microflow profiles at channels junction were examined, revealing that molecular diffusion played a significant role in the valving disable; which could cause analyte leakage in sample injection. Due to diffusion, the analyte crossed the interface of the analyte flow and gating flow, and then formed a cometic tail-like diffusion area at channels junction. From theoretical calculation and some experimental evidences, the size of the area was related to the diffusion coefficient and the velocity of analytes. Additionally, molecular diffusion was also believed to be another reason of sampling bias in gated injection.

Recent Development in Optical Chemical Sensors Coupling with Flow Injection Analysis

PubMed Central

Ojeda, Catalina Bosch; Rojas, Fuensanta Sánchez

2006-01-01

Optical techniques for chemical analysis are well established and sensors based on these techniques are now attracting considerable attention because of their importance in applications such as environmental monitoring, biomedical sensing, and industrial process control. On the other hand, flow injection analysis (FIA) is advisable for the rapid analysis of microliter volume samples and can be interfaced directly to the chemical process. The FIA has become a widespread automatic analytical method for more reasons; mainly due to the simplicity and low cost of the setups, their versatility, and ease of assembling. In this paper, an overview of flow injection determinations by using optical chemical sensors is provided, and instrumentation, sensor design, and applications are discussed. This work summarizes the most relevant manuscripts from 1980 to date referred to analysis using optical chemical sensors in FIA.

Performance of Pylons Upstream of a Cavity-Based Flameholder in Non-Reacting Supersonic Flow (Postprint)

DTIC Science & Technology

2006-10-01

examine the flow field at an axial location of 0.75 inches. Measurements are performed using a pitot , cone-static probe and total temperature probe ...is the injection port, and the origin of the transverse direction (y/d = 0.0) is the upstream lip of the cavity. In each figure, the bow shock ...originates just upstream of the injection port and tends to be the strongest shock feature. In the baseline configurations, the bow shock initially

Tracer-monitored flow titrations.

PubMed

Sasaki, Milton K; Rocha, Diogo L; Rocha, Fábio R P; Zagatto, Elias A G

2016-01-01

The feasibility of implementing tracer-monitored titrations in a flow system is demonstrated. A dye tracer is used to estimate the instant sample and titrant volumetric fractions without the need for volume, mass or peak width measurements. The approach was applied to spectrophotometric flow titrations involving variations of sample and titrant flow-rates (i.e. triangle programmed technique) or concentration gradients established along the sample zone (i.e. flow injection system). Both strategies required simultaneous monitoring of two absorbing species, namely the titration indicator and the dye tracer. Mixing conditions were improved by placing a chamber with mechanical stirring in the analytical path aiming at to minimize diffusional effects. Unlike most of flow-based titrations, the innovation is considered as a true titration, as it does not require a calibration curve thus complying with IUPAC definition. As an application, acidity evaluation in vinegars involving titration with sodium hydroxide was selected. Phenolphthalein and brilliant blue FCF were used as indicator and dye tracer, respectively. Effects of sample volume, titrand/titrant concentrations and flow rates were investigated aiming at improved accuracy and precision. Results were reliable and in agreement with those obtained by a reference titration procedure. Copyright © 2015 Elsevier B.V. All rights reserved.

Multiphase modeling of geologic carbon sequestration in saline aquifers.

PubMed

Bandilla, Karl W; Celia, Michael A; Birkholzer, Jens T; Cihan, Abdullah; Leister, Evan C

2015-01-01

Geologic carbon sequestration (GCS) is being considered as a climate change mitigation option in many future energy scenarios. Mathematical modeling is routinely used to predict subsurface CO2 and resident brine migration for the design of injection operations, to demonstrate the permanence of CO2 storage, and to show that other subsurface resources will not be degraded. Many processes impact the migration of CO2 and brine, including multiphase flow dynamics, geochemistry, and geomechanics, along with the spatial distribution of parameters such as porosity and permeability. In this article, we review a set of multiphase modeling approaches with different levels of conceptual complexity that have been used to model GCS. Model complexity ranges from coupled multiprocess models to simplified vertical equilibrium (VE) models and macroscopic invasion percolation models. The goal of this article is to give a framework of conceptual model complexity, and to show the types of modeling approaches that have been used to address specific GCS questions. Application of the modeling approaches is shown using five ongoing or proposed CO2 injection sites. For the selected sites, the majority of GCS models follow a simplified multiphase approach, especially for questions related to injection and local-scale heterogeneity. Coupled multiprocess models are only applied in one case where geomechanics have a strong impact on the flow. Owing to their computational efficiency, VE models tend to be applied at large scales. A macroscopic invasion percolation approach was used to predict the CO2 migration at one site to examine details of CO2 migration under the caprock. © 2015, National Ground Water Association.

Spike-Nosed Bodies and Forward Injected Jets in Supersonic Flow

NASA Technical Reports Server (NTRS)

Gilinsky, M.; Washington, C.; Blankson, I. M.; Shvets, A. I.

2002-01-01

The paper contains new numerical simulation and experimental test results of blunt body drag reduction using thin spikes mounted in front of a body and one- or two-phase jets injected against a supersonic flow. Numerical simulations utilizing the NASA CFL3D code were conducted at the Hampton University Fluid Mechanics and Acoustics Laboratory (FM&AL) and experimental tests were conducted using the facilities of the IM/MSU Aeromechanics and Gas Dynamics Laboratory. Previous results were presented at the 37th AIAA/ASME/SAE/ASEE Joint Propulsion Conference. Those results were based on some experimental and numerical simulation tests for supersonic flow around spike-nosed or shell-nosed bodies, and numerical simulations were conducted only for a single spike-nosed or shell-nosed body at zero attack angle, alpha=0. In this paper, experimental test results of gas, liquid and solid particle jet injection against a supersonic flow are presented. In addition, numerical simulation results for supersonic flow around a multiple spike-nosed body with non-zero attack angles and with a gas and solid particle forward jet injection are included. Aerodynamic coefficients: drag, C(sub D), lift, C(sub L), and longitudinal momentum, M(sub z), obtained by numerical simulation and experimental tests are compared and show good agreement.

Spike-Nosed Bodies and Forward Injected Jets in Supersonic Flow

NASA Technical Reports Server (NTRS)

Gilinsky, M.; Washington, C.; Blankson, I. M.; Shvets, A. I.

2002-01-01

The paper contains new numerical simulation and experimental test results of blunt body drag reduction using thin spikes mounted in front of a body and one- or two-phase jets injected against a supersonic flow. Numerical simulations utilizing the NASA CFL3D code were conducted at the Hampton University Fluid Mechanics and Acoustics Laboratory (FM&AL) and experimental tests were conducted using the facilities of the IM/MSU Aeromechanics and Gas Dynamics Laboratory. Previous results were presented at the 37th AIAA/ASME/SAE/ASEE Joint Propulsion Conference. Those results were based on some experimental and numerical simulation tests for supersonic flow around spike-nosed or shell-nosed bodies, and numerical simulations were conducted only for a single spike-nosed or shell-nosed body at zero attack angle, alpha = 0 degrees. In this paper, experimental test results of gas, liquid and solid particle jet injection against a supersonic flow are presented. In addition, numerical simulation results for supersonic flow around a multiple spike-nosed body with non-zero attack angles and with a gas and solid particle forward jet injection are included. Aerodynamic coefficients: drag, C (sub D), lift, C(sub L), and longitudinal momentum, M(sub z), obtained by numerical simulation and experimental tests are compared and show good agreement.

Dual-domain mass-transfer parameters from electrical hysteresis: theory and analytical approach applied to laboratory, synthetic streambed, and groundwater experiments

USGS Publications Warehouse

Briggs, Martin A.; Day-Lewis, Frederick D.; Ong, John B.; Harvey, Judson W.; Lane, John W.

2014-01-01

Models of dual-domain mass transfer (DDMT) are used to explain anomalous aquifer transport behavior such as the slow release of contamination and solute tracer tailing. Traditional tracer experiments to characterize DDMT are performed at the flow path scale (meters), which inherently incorporates heterogeneous exchange processes; hence, estimated “effective” parameters are sensitive to experimental design (i.e., duration and injection velocity). Recently, electrical geophysical methods have been used to aid in the inference of DDMT parameters because, unlike traditional fluid sampling, electrical methods can directly sense less-mobile solute dynamics and can target specific points along subsurface flow paths. Here we propose an analytical framework for graphical parameter inference based on a simple petrophysical model explaining the hysteretic relation between measurements of bulk and fluid conductivity arising in the presence of DDMT at the local scale. Analysis is graphical and involves visual inspection of hysteresis patterns to (1) determine the size of paired mobile and less-mobile porosities and (2) identify the exchange rate coefficient through simple curve fitting. We demonstrate the approach using laboratory column experimental data, synthetic streambed experimental data, and field tracer-test data. Results from the analytical approach compare favorably with results from calibration of numerical models and also independent measurements of mobile and less-mobile porosity. We show that localized electrical hysteresis patterns resulting from diffusive exchange are independent of injection velocity, indicating that repeatable parameters can be extracted under varied experimental designs, and these parameters represent the true intrinsic properties of specific volumes of porous media of aquifers and hyporheic zones.

Dual-domain mass-transfer parameters from electrical hysteresis: Theory and analytical approach applied to laboratory, synthetic streambed, and groundwater experiments

NASA Astrophysics Data System (ADS)

Briggs, Martin A.; Day-Lewis, Frederick D.; Ong, John B.; Harvey, Judson W.; Lane, John W.

2014-10-01

Models of dual-domain mass transfer (DDMT) are used to explain anomalous aquifer transport behavior such as the slow release of contamination and solute tracer tailing. Traditional tracer experiments to characterize DDMT are performed at the flow path scale (meters), which inherently incorporates heterogeneous exchange processes; hence, estimated "effective" parameters are sensitive to experimental design (i.e., duration and injection velocity). Recently, electrical geophysical methods have been used to aid in the inference of DDMT parameters because, unlike traditional fluid sampling, electrical methods can directly sense less-mobile solute dynamics and can target specific points along subsurface flow paths. Here we propose an analytical framework for graphical parameter inference based on a simple petrophysical model explaining the hysteretic relation between measurements of bulk and fluid conductivity arising in the presence of DDMT at the local scale. Analysis is graphical and involves visual inspection of hysteresis patterns to (1) determine the size of paired mobile and less-mobile porosities and (2) identify the exchange rate coefficient through simple curve fitting. We demonstrate the approach using laboratory column experimental data, synthetic streambed experimental data, and field tracer-test data. Results from the analytical approach compare favorably with results from calibration of numerical models and also independent measurements of mobile and less-mobile porosity. We show that localized electrical hysteresis patterns resulting from diffusive exchange are independent of injection velocity, indicating that repeatable parameters can be extracted under varied experimental designs, and these parameters represent the true intrinsic properties of specific volumes of porous media of aquifers and hyporheic zones.

Development of an automated flow injection analysis system for determination of phosphate in nutrient solutions.

PubMed

Karadağ, Sevinç; Görüşük, Emine M; Çetinkaya, Ebru; Deveci, Seda; Dönmez, Koray B; Uncuoğlu, Emre; Doğu, Mustafa

2018-01-25

A fully automated flow injection analysis (FIA) system was developed for determination of phosphate ion in nutrient solutions. This newly developed FIA system is a portable, rapid and sensitive measuring instrument that allows on-line analysis and monitoring of phosphate ion concentration in nutrient solutions. The molybdenum blue method, which is widely used in FIA phosphate analysis, was adapted to the developed FIA system. The method is based on the formation of ammonium Mo(VI) ion by reaction of ammonium molybdate with the phosphate ion present in the medium. The Mo(VI) ion then reacts with ascorbic acid and is reduced to the spectrometrically measurable Mo(V) ion. New software specific for flow analysis was developed in the LabVIEW development environment to control all the components of the FIA system. The important factors affecting the analytical signal were identified as reagent flow rate, injection volume and post-injection flow path length, and they were optimized using Box-Behnken experimental design and response surface methodology. The optimum point for the maximum analytical signal was calculated as 0.50 mL min -1 reagent flow rate, 100 µL sample injection volume and 60 cm post-injection flow path length. The proposed FIA system had a sampling frequency of 100 samples per hour over a linear working range of 3-100 mg L -1 (R 2  = 0.9995). The relative standard deviation (RSD) was 1.09% and the limit of detection (LOD) was 0.34 mg L -1 . Various nutrient solutions from a tomato-growing hydroponic greenhouse were analyzed with the developed FIA system and the results were found to be in good agreement with vanadomolybdate chemical method findings. © 2018 Society of Chemical Industry. © 2018 Society of Chemical Industry.

Rapid Quantitation of Ascorbic and Folic Acids in SRM 3280 Multivitamin/Multielement Tablets using Flow-Injection Tandem Mass Spectrometry

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bhandari, Deepak; Kertesz, Vilmos; Van Berkel, Gary J

RATIONALE: Ascorbic acid (AA) and folic acid (FA) are water-soluble vitamins and are usually fortified in food and dietary supplements. For the safety of human health, proper intake of these vitamins is recommended. Improvement in the analysis time required for the quantitative determination of these vitamins in food and nutritional formulations is desired. METHODS: A simple and fast (~5 min) in-tube sample preparation was performed, independently for FA and AA, by mixing extraction solvent with a powdered sample aliquot followed by agitation, centrifugation, and filtration to recover an extract for analysis. Quantitative detection was achieved by flow-injection (1 L injectionmore » volume) electrospray ionization tandem mass spectrometry (ESI-MS/MS) in negative ion mode using the method of standard addition. RESULTS: Method of standard addition was employed for the quantitative estimation of each vitamin in a sample extract. At least 2 spiked and 1 non-spiked sample extract were injected in triplicate for each quantitative analysis. Given an injection-to-injection interval of approximately 2 min, about 18 min was required to complete the quantitative estimation of each vitamin. The concentration values obtained for the respective vitamins in the standard reference material (SRM) 3280 using this approach were within the statistical range of the certified values provided in the NIST Certificate of Analysis. The estimated limit of detections of FA and AA were 13 and 5.9 ng/g, respectively. CONCLUSIONS: Flow-injection ESI-MS/MS was successfully applied for the rapid quantitation of FA and AA in SRM 3280 multivitamin/multielement tablets.« less

Modeling GPR data to interpret porosity and DNAPL saturations for calibration of a 3-D multiphase flow simulation

USGS Publications Warehouse

Sneddon, Kristen W.; Powers, Michael H.; Johnson, Raymond H.; Poeter, Eileen P.

2002-01-01

Dense nonaqueous phase liquids (DNAPLs) are a pervasive and persistent category of groundwater contamination. In an effort to better understand their unique subsurface behavior, a controlled and carefully monitored injection of PCE (perchloroethylene), a typical DNAPL, was performed in conjunction with the University of Waterloo at Canadian Forces Base Borden in 1991. Of the various geophysical methods used to monitor the migration of injected PCE, the U.S. Geological Survey collected 500-MHz ground penetrating radar (GPR) data. These data are used in determining calibration parameters for a multiphase flow simulation. GPR data were acquired over time on a fixed two-dimensional surficial grid as the DNAPL was injected into the subsurface. Emphasis is on the method of determining DNAPL saturation values from this time-lapse GPR data set. Interactive full-waveform GPR modeling of regularized field traces resolves relative dielectric permittivity versus depth profiles for pre-injection and later-time data. Modeled values are end members in recursive calculations of the Bruggeman-Hanai-Sen (BHS) mixing formula, yielding interpreted pre-injection porosity and post-injection DNAPL saturation values. The resulting interpreted physical properties of porosity and DNAPL saturation of the Borden test cell, defined on a grid spacing of 50 cm with 1-cm depth resolution, are used as observations for calibration of a 3-D multiphase flow simulation. Calculated values of DNAPL saturation in the subsurface at 14 and 22 hours after the start of injection, from both the GPR and the multiphase flow modeling, are interpolated volumetrically and presented for visual comparison.

Regional myocardial flow and capillary permeability-surface area products are nearly proportional.

PubMed

Caldwell, J H; Martin, G V; Raymond, G M; Bassingthwaighte, J B

1994-08-01

Analyses of data on the transcapillary exchange and cellular uptake in the normal heart have generally been based on the assumption that local membrane conductances and volumes of distribution are everywhere the same. The question is whether such an assumption is justified in view of the marked (sixfold) heterogeneity of local blood flows per gram tissue. The method was to estimate both flow and capillary membrane permeability-surface area products (PS) locally in the heart. For each of five dogs running on a sloped treadmill, the deposition of tracer microspheres and of [131I]iodophenylpentadecanoic acid (IPPA), after left atrial injection, was determined in 256 pieces of left ventricular myocardium by killing the animals at approximately 100 s after radiotracer injection. A hydraulic occluder stopped the flow to a portion of the myocardium supplied by the left circumflex coronary artery 30 s before tracer injection. Regional flows ranged from 0.1 to 7.0 ml.g-1.min-1. IPPA extractions ranged from 20 to 49%. Using the known flows, we assumed the applicability of an axially distributed blood-tissue exchange model to estimate the PS for the capillary (PSc) and the parenchymal cell. It was impossible to explain the data if the PSc values for membrane transport were uniform throughout the organ. Rather, the only reasonable descriptors of the data required that local PSc values increase with local flow, almost in proportion. Current methods of analysis using data based on deposition methods need to be revised to take into account the near proportionality of PS to flow for at least some substrates.

Flow injection method for the determination of silver concentration in drinking water for spacecrafts.

PubMed

Bruzzoniti, Maria Concetta; Kobylinska, Dorota Korte; Franko, Mladen; Sarzanini, Corrado

2010-04-14

A flow injection method has been developed for determination of silver. The method is based on a reduction reaction with sodium borohydride which leads to the formation of a colloidal species which is monitored at a wavelength of 390 nm. The reaction variables flow rate, sodium borohydride concentration and pH, which affect sensitivity, were investigated and their effects were established using a two-levels, three-factor experimental design. Further optimization of manifold variables (reaction coil and injection volume) allowed us to determine silver in the range 0.050-5.0 mg L(-1) with a minimum detectable concentration of 0.050 mg L(-1). Silver is added, as biocide, to drinking water for spacecrafts. The chemical species of silver, present in this kind of sample, were characterized by a procedure based on the selective retention of Ag(+) onto a 2.2.2. cryptand based substrate followed by determination of the non-bound and bound (after elution) Ag(+) by the FIA method. The method optimized was applied to a drinking water sample provided for the launch with the Automated Transfer Vehicle (ATV) module Jule Verne to the International Space Station (March 9, 2008). Copyright 2010 Elsevier B.V. All rights reserved.

Two dissimilar approaches to dynamical systems on hyper MV -algebras and their information entropy

NASA Astrophysics Data System (ADS)

Mehrpooya, Adel; Ebrahimi, Mohammad; Davvaz, Bijan

2017-09-01

Measuring the flow of information that is related to the evolution of a system which is modeled by applying a mathematical structure is of capital significance for science and usually for mathematics itself. Regarding this fact, a major issue in concern with hyperstructures is their dynamics and the complexity of the varied possible dynamics that exist over them. Notably, the dynamics and uncertainty of hyper MV -algebras which are hyperstructures and extensions of a central tool in infinite-valued Lukasiewicz propositional calculus that models many valued logics are of primary concern. Tackling this problem, in this paper we focus on the subject of dynamical systems on hyper MV -algebras and their entropy. In this respect, we adopt two varied approaches. One is the set-based approach in which hyper MV -algebra dynamical systems are developed by employing set functions and set partitions. By the other method that is based on points and point partitions, we establish the concept of hyper injective dynamical systems on hyper MV -algebras. Next, we study the notion of entropy for both kinds of systems. Furthermore, we consider essential ergodic characteristics of those systems and their entropy. In particular, we introduce the concept of isomorphic hyper injective and hyper MV -algebra dynamical systems, and we demonstrate that isomorphic systems have the same entropy. We present a couple of theorems in order to help calculate entropy. In particular, we prove a contemporary version of addition and Kolmogorov-Sinai Theorems. Furthermore, we provide a comparison between the indispensable properties of hyper injective and semi-independent dynamical systems. Specifically, we present and prove theorems that draw comparisons between the entropies of such systems. Lastly, we discuss some possible relationships between the theories of hyper MV -algebra and MV -algebra dynamical systems.

A Customizable Flow Injection System for Automated, High Throughput, and Time Sensitive Ion Mobility Spectrometry and Mass Spectrometry Measurements

DOE Office of Scientific and Technical Information (OSTI.GOV)

Orton, Daniel J.; Tfaily, Malak M.; Moore, Ronald J.

To better understand disease conditions and environmental perturbations, multi-omic studies (i.e. proteomic, lipidomic, metabolomic, etc. analyses) are vastly increasing in popularity. In a multi-omic study, a single sample is typically extracted in multiple ways and numerous analyses are performed using different instruments. Thus, one sample becomes many analyses, making high throughput and reproducible evaluations a necessity. One way to address the numerous samples and varying instrumental conditions is to utilize a flow injection analysis (FIA) system for rapid sample injection. While some FIA systems have been created to address these challenges, many have limitations such as high consumable costs, lowmore » pressure capabilities, limited pressure monitoring and fixed flow rates. To address these limitations, we created an automated, customizable FIA system capable of operating at diverse flow rates (~50 nL/min to 500 µL/min) to accommodate low- and high-flow instrument sources. This system can also operate at varying analytical throughputs from 24 to 1200 samples per day to enable different MS analysis approaches. Applications ranging from native protein analyses to molecular library construction were performed using the FIA system. The results from these studies showed a highly robust platform, providing consistent performance over many days without carryover as long as washing buffers specific to each molecular analysis were utilized.« less

Three-dimensional numerical simulation for plastic injection-compression molding

NASA Astrophysics Data System (ADS)

Zhang, Yun; Yu, Wenjie; Liang, Junjie; Lang, Jianlin; Li, Dequn

2018-03-01

Compared with conventional injection molding, injection-compression molding can mold optical parts with higher precision and lower flow residual stress. However, the melt flow process in a closed cavity becomes more complex because of the moving cavity boundary during compression and the nonlinear problems caused by non-Newtonian polymer melt. In this study, a 3D simulation method was developed for injection-compression molding. In this method, arbitrary Lagrangian- Eulerian was introduced to model the moving-boundary flow problem in the compression stage. The non-Newtonian characteristics and compressibility of the polymer melt were considered. The melt flow and pressure distribution in the cavity were investigated by using the proposed simulation method and compared with those of injection molding. Results reveal that the fountain flow effect becomes significant when the cavity thickness increases during compression. The back flow also plays an important role in the flow pattern and redistribution of cavity pressure. The discrepancy in pressures at different points along the flow path is complicated rather than monotonically decreased in injection molding.

Determination of mercury by multisyringe flow injection system with cold-vapor atomic absorption spectrometry.

PubMed

Leal, L O; Elsholz, O; Forteza, R; Cerdà, V

2006-07-28

A new software-controlled time-based multisyringe flow injection system for mercury determination by cold-vapor atomic absorption spectrometry is proposed. Precise known volumes of sample, reducing agent (1.1% SnCl2 in 3% HCl) and carrier (3% HCl) are dispensed into a gas-liquid separation cell with a multisyringe burette coupled with one three-way solenoid valve. An argon flow delivers the reduced mercury to the spectrometer. The optimization of the system was carried out testing reaction coils and gas-liquid separators of different design as well as changing parameters, such as sample and reagents volumes, reagent concentrations and carrier gas flow rate, among others. The analytical curves were obtained within the range 50-5000 ng L(-1). The detection limit (3sigma(b)/S) achieved is 5 ng L(-1). The relative standard deviation (R.S.D.) was 1.4%, evaluated from 16 successive injections of 250 ng L(-1) Hg standard solution. The injection and sample throughput per hour were 44 and 11, respectively. This technique was validated by means of solid and water reference materials with good agreement with the certified values and was successfully applied to fish samples.

Integration of a Capacitive EIS Sensor into a FIA System for pH and Penicillin Determination

PubMed Central

Rolka, David; Poghossian, Arshak; Schöning, Michael J.

2004-01-01

A field-effect based capacitive EIS (electrolyte-insulator-semiconductor) sensor with a p-Si-SiO2-Ta2O5 structure has been successfully integrated into a commercial FIA (flow-injection analysis) system and system performances have been proven and optimised for pH and penicillin detection. A flow-through cell was designed taking into account the requirement of a variable internal volume (from 12 μl up to 48 μl) as well as an easy replacement of the EIS sensor. FIA parameters (sample volume, flow rate, distance between the injection valve and the EIS sensor) have been optimised in terms of high sensitivity and reproducibility as well as a minimum dispersion of the injected sample zone. An acceptable compromise between different FIA parameters has been found. For the cell design used in this study, best results have been achieved with a flow rate of 1.4 ml/min, distance between the injection valve and the EIS sensor of 6.5 cm, probe volume of 0.75 ml, cell internal volume of 12 μl. A sample throughput of at least 15 samples/h was typically obtained.

Injection System for Multi-Well Injection Using a Single Pump

PubMed Central

Wovkulich, Karen; Stute, Martin; Protus, Thomas J.; Mailloux, Brian J.; Chillrud, Steven N.

2015-01-01

Many hydrological and geochemical studies rely on data resulting from injection of tracers and chemicals into groundwater wells. The even distribution of liquids to multiple injection points can be challenging or expensive, especially when using multiple pumps. An injection system was designed using one chemical metering pump to evenly distribute the desired influent simultaneously to 15 individual injection points through an injection manifold. The system was constructed with only one metal part contacting the fluid due to the low pH of the injection solutions. The injection manifold system was used during a three-month pilot scale injection experiment at the Vineland Chemical Company Superfund site. During the two injection phases of the experiment (Phase I = 0.27 L/min total flow, Phase II = 0.56 L/min total flow), flow measurements were made 20 times over three months; an even distribution of flow to each injection well was maintained (RSD <4%). This durable system is expandable to at least 16 injection points and should be adaptable to other injection experiments that require distribution of air-stable liquids to multiple injection points with a single pump. PMID:26140014

Numerical Simulation of Atomization in Nozzle Injection Flow

NASA Astrophysics Data System (ADS)

Fan, Qinyin; Guo, Chenhai; Takagi, Tosimi; Narumiya, Kikuo; Hattori, Hiroshi

At the initial stage of injection, the injection flow has not yet broken up and in a range of small atmosphere pressure (16˜500KPa), the tip of the injection flow always forms a shape of mushroom. [1] [2] Moreover, the umbrella of the mushroom is always very big and its root is always very thin, especially when the atmosphere pressure is relatively low (88KPa, or 100mmHg). These phenomena are not known popularly and the reason of mushroom formation is not clear. In this paper, with the MARS method for simulating free surface, analysis of injection flow is practiced. The phenomena are reproduced and the reason is cleared that the formation of the mushroom is induced by the momentum exchange between the injection fuel flow with very high speed and the very complex flow of the air.

A novel approach for determination of free fatty acids in vegetable oils by a flow injection system with manual injection.

PubMed

Ayyildiz, H Filiz; Kara, Huseyin; Sherazi, S T H

2011-12-01

A non-aqueous flow injection method for determining free fatty acid (FFA) content in corn and sunflower oil samples was developed. A single-line manifold system was built by modification of an HPLC for flow injection analysis (FIA). Without pre-treatment, oil samples were injected into a n-propanol solution containing KOH and phenolphthalein (PHP). The main parameters, such as flow rate of carrier phase, length, geometry, inner diameters of the coils and reagent concentration were all optimized. The proposed FIA method was validated for precision, accuracy, linear region, limit of detection (LOD) and limit of quantification (LOQ). The intra- and inter-day measurements of the precision of the method were found to be within the limits of acceptance criteria (RSD < 1%), and were rugged when the method was performed by a different analyst. The linear concentration range was calculated as 0.09-1.50 and 0.07-1.40 FFA% for corn and sunflower oils, correspondingly. The LOD and LOQ were found to be 7.53 × 10(-4)-2.28 × 10(-3) oleic acid % and 7.11 × 10(-4)-2.23 × 10(-3) oleic acid % for corn and sunflower oils, respectively. The results were compared with those obtained by the AOCS (Ca-5a-40) method using statistical t and F tests, and a significant difference was not observed between the methods at a 95% confidence level. The proposed method is suitable for quality control of routine applications due to its simplicity, high sample throughput, and economy of solvents and sample, offering considerable promise as a low cost analytical system that needs minimum human intervention over long periods of time.

Investigation of combustion characteristics in a scramjet combustor using a modified flamelet model

NASA Astrophysics Data System (ADS)

Zhao, Guoyan; Sun, Mingbo; Wang, Hongbo; Ouyang, Hao

2018-07-01

In this study, the characteristics of supersonic combustion inside an ethylene-fueled scramjet combustor equipped with multi-cavities were investigated with different injection schemes. Experimental results showed that the flames concentrated in the cavity and separated boundary layer downstream of the cavity, and they occupied the flow channel further enhancing the bulk flow compression. The flame structure in distributed injection scheme differed from that in centralized injection scheme. In numerical simulations, a modified flamelet model was introduced to consider that the pressure distribution is far from homogenous inside the scramjet combustor. Compared with original flamelet model, numerical predictions based on the modified model showed better agreement with the experimental results, validating the reliability of the calculations. Based on the modified model, the simulations with different injection schemes were analysed. The predicted flame agreed reasonably with the experimental observations in structure. The CO masses were concentrated in cavity and subsonic region adjacent to the cavity shear layer leading to intense heat release. Compared with centralized scheme, the higher jet mixing efficiency in distributed scheme induced an intense combustion in posterior upper cavity and downstream of the cavity. From streamline and isolation surfaces, the combustion at trail of lower cavity was depressed since the bulk flow downstream of the cavity is pushed down.

Large-Eddy/Lattice Boltzmann Simulations of Micro-blowing Strategies for Subsonic and Supersonic Drag Control

NASA Technical Reports Server (NTRS)

Menon, Suresh

2003-01-01

This report summarizes the progress made in the first 8 to 9 months of this research. The Lattice Boltzmann Equation (LBE) methodology for Large-eddy Simulations (LES) of microblowing has been validated using a jet-in-crossflow test configuration. In this study, the flow intake is also simulated to allow the interaction to occur naturally. The Lattice Boltzmann Equation Large-eddy Simulations (LBELES) approach is capable of capturing not only the flow features associated with the flow, such as hairpin vortices and recirculation behind the jet, but also is able to show better agreement with experiments when compared to previous RANS predictions. The LBELES is shown to be computationally very efficient and therefore, a viable method for simulating the injection process. Two strategies have been developed to simulate multi-hole injection process as in the experiment. In order to allow natural interaction between the injected fluid and the primary stream, the flow intakes for all the holes have to be simulated. The LBE method is computationally efficient but is still 3D in nature and therefore, there may be some computational penalty. In order to study a large number or holes, a new 1D subgrid model has been developed that will simulate a reduced form of the Navier-Stokes equation in these holes.

Numerical modeling of experimental observations on gas formation and multi-phase flow of carbon dioxide in subsurface formations

NASA Astrophysics Data System (ADS)

Pawar, R.; Dash, Z.; Sakaki, T.; Plampin, M. R.; Lassen, R. N.; Illangasekare, T. H.; Zyvoloski, G.

2011-12-01

One of the concerns related to geologic CO2 sequestration is potential leakage of CO2 and its subsequent migration to shallow groundwater resources leading to geochemical impacts. Developing approaches to monitor CO2 migration in shallow aquifer and mitigate leakage impacts will require improving our understanding of gas phase formation and multi-phase flow subsequent to CO2 leakage in shallow aquifers. We are utilizing an integrated approach combining laboratory experiments and numerical simulations to characterize the multi-phase flow of CO2 in shallow aquifers. The laboratory experiments involve a series of highly controlled experiments in which CO2 dissolved water is injected in homogeneous and heterogeneous soil columns and tanks. The experimental results are used to study the effects of soil properties, temperature, pressure gradients and heterogeneities on gas formation and migration. We utilize the Finite Element Heat and Mass (FEHM) simulator (Zyvoloski et al, 2010) to numerically model the experimental results. The numerical models capture the physics of CO2 exsolution, multi-phase fluid flow as well as sand heterogeneity. Experimental observations of pressure, temperature and gas saturations are used to develop and constrain conceptual models for CO2 gas-phase formation and multi-phase CO2 flow in porous media. This talk will provide details of development of conceptual models based on experimental observation, development of numerical models for laboratory experiments and modelling results.

Determination of 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride by flow-injection analysis based on a specific condensation reaction between malonic acid and ethylenediamine.

PubMed

Seno, Kunihiko; Matumura, Kazuki; Oshita, Koji; Oshima, Mitsuko; Motomizu, Shoji

2009-03-01

A sensitive and rapid flow-injection analysis was developed for the determination of 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC.HCl), which was used for the formation of amide (peptide) and esters as a dehydration or condensation reagent. The EDC.HCl could be determined by the flow-injection analysis based on a specific condensation reaction between malonic acid and ethylenediamine in aquatic media. The reaction was accelerated at 60 degrees C, and the absorbance of the product was detected at 262 nm. The calibration graph of EDC.HCl showed good linearity in the range from 0 to 0.1% (0 to 0.0005 M), whose regression equation was y = 1.52 x 10(9)x (y, peak area; x, % concentration of EDC.HCl). The proposed method allowed high-throughput analysis; the sample throughput was 12 samples per hour. The limit of detection (LOD) and the relative standard deviation (RSD) were 2 x 10(-6) M and 1.0%, respectively. This reaction is proceeded in aqueous solution and specific for EDC.HCl.

Chemometrics-assisted simultaneous determination of cobalt(II) and chromium(III) with flow-injection chemiluminescence method

NASA Astrophysics Data System (ADS)

Li, Baoxin; Wang, Dongmei; Lv, Jiagen; Zhang, Zhujun

2006-09-01

In this paper, a flow-injection chemiluminescence (CL) system is proposed for simultaneous determination of Co(II) and Cr(III) with partial least squares calibration. This method is based on the fact that both Co(II) and Cr(III) catalyze the luminol-H 2O 2 CL reaction, and that their catalytic activities are significantly different on the same reaction condition. The CL intensity of Co(II) and Cr(III) was measured and recorded at different pH of reaction medium, and the obtained data were processed by the chemometric approach of partial least squares. The experimental calibration set was composed with nine sample solutions using orthogonal calibration design for two component mixtures. The calibration curve was linear over the concentration range of 2 × 10 -7 to 8 × 10 -10 and 2 × 10 -6 to 4 × 10 -9 g/ml for Co(II) and Cr(III), respectively. The proposed method offers the potential advantages of high sensitivity, simplicity and rapidity for Co(II) and Cr(III) determination, and was successfully applied to the simultaneous determination of both analytes in real water sample.

Iodine speciation in coastal and inland bathing waters and seaweeds extracts using a sequential injection standard addition flow-batch method.

PubMed

Santos, Inês C; Mesquita, Raquel B R; Bordalo, Adriano A; Rangel, António O S S

2015-02-01

The present work describes the development of a sequential injection standard addition method for iodine speciation in bathing waters and seaweeds extracts without prior sample treatment. Iodine speciation was obtained by assessing the iodide and iodate content, the two inorganic forms of iodine in waters. For the determination of iodide, an iodide ion selective electrode (ISE) was used. The indirect determination of iodate was based on the spectrophotometric determination of nitrite (Griess reaction). For the iodate measurement, a mixing chamber was employed (flow batch approach) to explore the inherent efficient mixing, essential for the indirect determination of iodate. The application of the standard addition method enabled detection limits of 0.14 µM for iodide and 0.02 µM for iodate, together with the direct introduction of the target water samples, coastal and inland bathing waters. The results obtained were in agreement with those obtained by ICP-MS and a colorimetric reference procedure. Recovery tests also confirmed the accuracy of the developed method which was effectively applied to bathing waters and seaweed extracts. Copyright © 2014 Elsevier B.V. All rights reserved.

Design, fabrication and delivery of a prototype saturator for ACPL

NASA Technical Reports Server (NTRS)

Keyser, G.; Rogers, C. F.; Squires, P.

1979-01-01

The design configuration and performance characteristics of a saturator developed to provide ground-based simulation for some of the experiments for ACPL-1 first flights of Spacelab are described, some difficulties encountered with the apparatus are discussed, and recommendations concerning testing of this type of instrument are presented. The saturators provide a means of accurately fixing the water vapor mixing ratio of an aerosol sample. Dew point temperatures from almost freezing to ambient room temperatures can be attained with high precision. The instruments can accommodate aerosol flow rates approaching 1000 cc/s. Provisions were made to inject aerosols upstream of these saturators, although downstream injection can be accomplished as well. A device of this type will be used in the ACPL-1 to condition various aerosols delivered concurrently to a CFD, expansion chamber, and static diffusion chamber used in zero gravity cloud-forming experiments. The saturator was designed to meet the requirements projected for the flight instrument.

Stream-wise distribution of skin-friction drag reduction on a flat plate with bubble injection

NASA Astrophysics Data System (ADS)

Qin, Shijie; Chu, Ning; Yao, Yan; Liu, Jingting; Huang, Bin; Wu, Dazhuan

2017-03-01

To investigate the stream-wise distribution of skin-friction drag reduction on a flat plate with bubble injection, both experiments and simulations of bubble drag reduction (BDR) have been conducted in this paper. Drag reductions at various flow speeds and air injection rates have been tested in cavitation tunnel experiments. Visualization of bubble flow pattern is implemented synchronously. The computational fluid dynamics (CFD) method, in the framework of Eulerian-Eulerian two fluid modeling, coupled with population balance model (PBM) is used to simulate the bubbly flow along the flat plate. A wide range of bubble sizes considering bubble breakup and coalescence is modeled based on experimental bubble distribution images. Drag and lift forces are fully modeled based on applicable closure models. Both predicted drag reductions and bubble distributions are in reasonable concordance with experimental results. Stream-wise distribution of BDR is revealed based on CFD-PBM numerical results. In particular, four distinct regions with different BDR characteristics are first identified and discussed in this study. Thresholds between regions are extracted and discussed. And it is highly necessary to fully understand the stream-wise distribution of BDR in order to establish a universal scaling law. Moreover, mechanism of stream-wise distribution of BDR is analysed based on the near-wall flow parameters. The local drag reduction is a direct result of near-wall max void fraction. And the near-wall velocity gradient modified by the presence of bubbles is considered as another important factor for bubble drag reduction.

Integration of continuous-flow sampling with microchip electrophoresis using poly(dimethylsiloxane)-based valves in a reversibly sealed device.

PubMed

Li, Michelle W; Martin, R Scott

2007-07-01

Here we describe a reversibly sealed microchip device that incorporates poly(dimethylsiloxane) (PDMS)-based valves for the rapid injection of analytes from a continuously flowing stream into a channel network for analysis with microchip electrophoresis. The microchip was reversibly sealed to a PDMS-coated glass substrate and microbore tubing was used for the introduction of gas and fluids to the microchip device. Two pneumatic valves were incorporated into the design and actuated on the order of hundreds of milliseconds, allowing analyte from a continuously flowing sampling stream to be injected into an electrophoresis separation channel. The device was characterized in terms of the valve actuation time and pushback voltage. It was also found that the addition of sodium dodecyl sulfate (SDS) to the buffer system greatly increased the reproducibility of the injection scheme and enabled the analysis of amino acids derivatized with naphthalene-2,3-dicarboxaldehyde/cyanide. Results from continuous injections of a 0.39 nL fluorescein plug into the optimized system showed that the injection process was reproducible (RSD of 0.7%, n = 10). Studies also showed that the device was capable of monitoring off-chip changes in concentration with a device lag time of 90 s. Finally, the ability of the device to rapidly monitor on-chip concentration changes was demonstrated by continually sampling from an analyte plug that was derivatized upstream from the electrophoresis/continuous flow interface. A reversibly sealed device of this type will be useful for the continuous monitoring and analysis of processes that occur either off-chip (such as microdialysis sampling) or on-chip from other integrated functions.

Hydraulic and Mechanical Effects from Gas Hydrate Conversion and Secondary Gas Hydrate Formation during Injection of CO2 into CH4-Hydrate-Bearing Sediments

NASA Astrophysics Data System (ADS)

Bigalke, N.; Deusner, C.; Kossel, E.; Schicks, J. M.; Spangenberg, E.; Priegnitz, M.; Heeschen, K. U.; Abendroth, S.; Thaler, J.; Haeckel, M.

2014-12-01

The injection of CO2 into CH4-hydrate-bearing sediments has the potential to drive natural gas production and simultaneously sequester CO2 by hydrate conversion. The process aims at maintaining the in situ hydrate saturation and structure and causing limited impact on soil hydraulic properties and geomechanical stability. However, to increase hydrate conversion yields and rates it must potentially be assisted by thermal stimulation or depressurization. Further, secondary formation of CO2-rich hydrates from pore water and injected CO2 enhances hydrate conversion and CH4 production yields [1]. Technical stimulation and secondary hydrate formation add significant complexity to the bulk conversion process resulting in spatial and temporal effects on hydraulic and geomechanical properties that cannot be predicted by current reservoir simulation codes. In a combined experimental and numerical approach, it is our objective to elucidate both hydraulic and mechanical effects of CO2 injection and CH4-CO2-hydrate conversion in CH4-hydrate bearing soils. For the experimental approach we used various high-pressure flow-through systems equipped with different online and in situ monitoring tools (e.g. Raman microscopy, MRI and ERT). One particular focus was the design of triaxial cell experimental systems, which enable us to study sample behavior even during large deformations and particle flow. We present results from various flow-through high-pressure experimental studies on different scales, which indicate that hydraulic and geomechanical properties of hydrate-bearing sediments are drastically altered during and after injection of CO2. We discuss the results in light of the competing processes of hydrate dissociation, hydrate conversion and secondary hydrate formation. Our results will also contribute to the understanding of effects of temperature and pressure changes leading to dissociation of gas hydrates in ocean and permafrost systems. [1] Deusner C, Bigalke N, Kossel E, Haeckel M. Methane Production from Gas Hydrate Deposits through Injection of Supercritical CO2. Energies 2012:5(7): 2112-2140.

THERMO-HYDRO-MECHANICAL MODELING OF WORKING FLUID INJECTION AND THERMAL ENERGY EXTRACTION IN EGS FRACTURES AND ROCK MATRIX

DOE Office of Scientific and Technical Information (OSTI.GOV)

Robert Podgorney; Chuan Lu; Hai Huang

2012-01-01

Development of enhanced geothermal systems (EGS) will require creation of a reservoir of sufficient volume to enable commercial-scale heat transfer from the reservoir rocks to the working fluid. A key assumption associated with reservoir creation/stimulation is that sufficient rock volumes can be hydraulically fractured via both tensile and shear failure, and more importantly by reactivation of naturally existing fractures (by shearing), to create the reservoir. The advancement of EGS greatly depends on our understanding of the dynamics of the intimately coupled rock-fracture-fluid-heat system and our ability to reliably predict how reservoirs behave under stimulation and production. Reliable performance predictions ofmore » EGS reservoirs require accurate and robust modeling for strongly coupled thermal-hydrological-mechanical (THM) processes. Conventionally, these types of problems have been solved using operator-splitting methods, usually by coupling a subsurface flow and heat transport simulators with a solid mechanics simulator via input files. An alternative approach is to solve the system of nonlinear partial differential equations that govern multiphase fluid flow, heat transport, and rock mechanics simultaneously, using a fully coupled, fully implicit solution procedure, in which all solution variables (pressure, enthalpy, and rock displacement fields) are solved simultaneously. This paper describes numerical simulations used to investigate the poro- and thermal- elastic effects of working fluid injection and thermal energy extraction on the properties of the fractures and rock matrix of a hypothetical EGS reservoir, using a novel simulation software FALCON (Podgorney et al., 2011), a finite element based simulator solving fully coupled multiphase fluid flow, heat transport, rock deformation, and fracturing using a global implicit approach. Investigations are also conducted on how these poro- and thermal-elastic effects are related to fracture permeability evolution.« less

Demonstration of An Integrated Approach to Mercury Control at Lee Station

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vitali Lissianski; Pete Maly

2007-12-31

General Electric (GE) has developed an approach whereby native mercury reduction on fly ash can be improved by optimizing the combustion system. This approach eliminates carbon-rich areas in the combustion zone, making the combustion process more uniform, and allows increasing carbon content in fly ash without significant increase in CO emissions. Since boiler excess O{sub 2} can be also reduced as a result of optimized combustion, this process reduces NO{sub x} emissions. Because combustion optimization improves native mercury reduction on fly ash, it can reduce requirements for activated carbon injection (ACI) when integrated with sorbent injection for more efficient mercurymore » control. The approach can be tailored to specific unit configurations and coal types for optimal performance. This report describes results of a U.S. DOE sponsored project designed to evaluate the effect of combustion conditions on 'native' mercury capture on fly ash and integrate combustion optimization for improved mercury and NO{sub x} reduction with ACI. The technology evaluation took place in Lee Station Unit 3 located in Goldsboro, NC and operated by Progress Energy. Unit 3 burns a low-sulfur Eastern bituminous coal and is a 250 MW opposed-wall fired unit equipped with an ESP with a specific collection area of 249 ft{sup 2}/kacfm. Unit 3 is equipped with SO{sub 3} injection for ESP conditioning. The technical goal of the project was to evaluate the technology's ability to achieve 70% mercury reduction below the baseline emission value of 2.9 lb/TBtu, which was equivalent to 80% mercury reduction relative to the mercury concentration in the coal. The strategy to achieve the 70% incremental improvement in mercury removal in Unit 3 was (1) to enhance 'naturally' occurring fly ash mercury capture by optimizing the combustion process and using duct humidification to reduce flue gas temperatures at the ESP inlet, and (2) to use ACI in front of the ESP to further reduce mercury emissions. The program was comprised of field and pilot-scale tests, engineering studies and consisted of eight tasks. As part of the program, GE conducted pilot-scale evaluation of sorbent effect on mercury reduction, supplied and installed adjustable riffle boxes to assist in combustion optimization, performed combustion optimization, supplied mobile sorbent injection and flue gas humidification systems, conducted CFD modeling of sorbent injection and flue gas humidification, and performed mercury testing including a continuous 30-day sorbent injection trial. Combustion optimization was the first step in reduction of mercury emissions. Goals of combustion optimization activities were to improve 'native' mercury capture on fly ash and reduce NO{sub x}. Combustion optimization included balancing of coal flow through individual burners to eliminate zones of carbon-rich combustion, air flow balancing, and burner adjustments. As part of the project, the original riffle boxes were replaced with Foster-Wheeler's adjustable riffle boxes to allow for biasing the coal flow between the coal pipes. A 10-point CO/O{sub 2}/NO{sub x} grid was installed in the primary superheater region of the back pass to assist in these activities. Testing of mercury emissions before and after combustion optimization demonstrated that mercury emissions were reduced from 2.9 lb/TBtu to 1.8 lb/TBtu due to boiler operation differences in conjunction with combustion optimization, a 38% improvement in 'native' mercury capture on fly ash. Native mercury reduction from coal was {approx}42% at baseline conditions and 64% at optimized combustion conditions. As a result of combustion optimization NO{sub x} emissions were reduced by 18%. A three-dimensional CFD model was developed to study the flow distribution and sorbent injection in the post air heater duct in Lee Station Unit 3. Modeling of the flow pattern exiting the air pre-heater demonstrated that because of the duct transition from a circular opening at the exit of air-pre-heater to a rectangular ESP inlet duct, flow separation occurred at the corners after the transition. Modeling also demonstrated that the flow was severely biased from the South side to the North side due to the bend of the duct. Results of CFD modeling were used to design lances for better sorbent distribution across the ESP inlet duct. Modeling of water injection demonstrated that because of flue gas temperature biasing, the droplet evaporation rate was slower on the North side than that on the South side of the duct. Modeling suggested that an improvement of water droplet evaporation could be achieved by closing the lance on the North side where flue gas temperatures were lower. Preliminary evaluation of the effect of carbon-based sorbents on mercury reduction took place in a 1 MBtu/hr (300 kW) Boiler Simulator Facility using the same coal as fired at Lee Station.« less

Chemiluminescence determination of ferulic acid by flow-injection analysis using cerium(IV) sensitized by rhodamine 6G.

PubMed

Wang, Ju Peng; Li, Nian Bing; Luo, Hong Qun

2008-11-01

A simple, sensitive and rapid flow-injection chemiluminescence method has been developed for the determination of ferulic acid based on the chemiluminescence reaction of ferulic acid with rhodamine 6G and ceric sulfate in sulphuric acid medium. Strong chemiluminescence signal was observed when ferulic acid was injected into the acidic ceric sulfate solution in a flow-cell. The present method allowed the determination of ferulic acid in the concentration range of 8.0 x 10(-6) to 1.0 x 10(-4) mol l(-1) and the detection limit for ferulic acid was 8.7 x 10(-9) mol l(-1). The relative standard deviation was 2.4% for 10 replicate analyses of 1.0 x 10(-5) mol l(-1) ferulic acid. The proposed method was applied to the determination of ferulic acid in Taita Beauty Essence samples with satisfactory results.

Chemiluminescence determination of ferulic acid by flow-injection analysis using cerium(IV) sensitized by rhodamine 6G

NASA Astrophysics Data System (ADS)

Wang, Ju Peng; Li, Nian Bing; Luo, Hong Qun

2008-11-01

A simple, sensitive and rapid flow-injection chemiluminescence method has been developed for the determination of ferulic acid based on the chemiluminescence reaction of ferulic acid with rhodamine 6G and ceric sulfate in sulphuric acid medium. Strong chemiluminescence signal was observed when ferulic acid was injected into the acidic ceric sulfate solution in a flow-cell. The present method allowed the determination of ferulic acid in the concentration range of 8.0 × 10 -6 to 1.0 × 10 -4 mol l -1 and the detection limit for ferulic acid was 8.7 × 10 -9 mol l -1. The relative standard deviation was 2.4% for 10 replicate analyses of 1.0 × 10 -5 mol l -1 ferulic acid. The proposed method was applied to the determination of ferulic acid in Taita Beauty Essence samples with satisfactory results.

Nonlinear Acoustic Processes in a Solid Rocket Engine

DTIC Science & Technology

1994-03-29

conceptual framwork for the study number (M), weakly viscous internal flow sustained of solid rocket engine chamber flow dynamics which by mass...same magnitude. The formulation and results provide a conceptual framwork for the study of injected cylinder flow dynamics which supplements traditional...towards the axial direction. Until recently, conceptual understanding of this flow turning process has been based largely on the viscous properties of the

Simulation of the injection of colloidal suspensions for the remediation of contaminated aquifer systems

NASA Astrophysics Data System (ADS)

Tosco, Tiziana; Gastone, Francesca; Sethi, Rajandrea

2014-05-01

Concentrated suspensions of microscale and nanoscale zerovalent iron particles (MZVI and NZVI) have been studied in recent years for the remediation of contaminated aquifers. The suspensions are injected into the subsurface to generate a reactive zone, and consequently the prediction of the particles distribution during the injection is a key aspect in the design of a field-scale injection. Colloidal dispersions of MZVI and NZVI are not stable in pure water, and shear thinning, environmentally friendly fluids (guar gum and xanthan gum solutions) were found to be effective in improving colloidal stability, thus greatly improving handling and injectability (1 - 3). Shear thinning fluids exhibit high viscosity in static conditions, improving the colloidal stability, and lower viscosity at high flow rates enabling the injection at limited pressures. Shear thinning fluids exhibit high viscosity in static conditions, improving the colloidal stability, and lower viscosity at high flow rates enabling the injection at limited pressures. In this work, co-funded by European Union project AQUAREHAB (FP7 - Grant Agreement Nr. 226565), laboratory and pilot field tests for MZVI injection in saturated porous media are reported. MZVI was dispersed in guar gum solutions, and the transport behaviour under several polymer concentrations and injection rates was assessed in column tests (4). Based on the experimental results, a modelling approach is proposed to simulate the transport in porous media of nanoscale iron slurries, implemented in E-MNM1D (www.polito.it/groundwater/software). Colloid transport mechanisms are controlled by particle-collector and particle-particle interactions, usually modelled by a non equilibrium kinetic model accounting for deposition and release processes. The key aspects included in the E-MNM1D are clogging phenomena (i.e. reduction of porosity and permeability due to particles deposition), and the rheological properties of the carrier fluid (in this project, guar gum solution). The influence of colloid transport on porosity, permeability, and fluid viscosity is explicitly lumped into the model and the shear-thinning nature of the iron slurries is described by a modified Darcy law generalized for non Newtonian fluids. Since during the injection in wells the velocity field is not constant over the distance, E-MNM1D was modified in order to account for variable colloidal transport coefficients on flow rate thus allowing the estimation of the radius of influence during a full scale intervention. The flow and transport of MZVI slurries is solved in a radial domain for the simulation of field-scale injection, incorporating the abovementioned relevant mechanisms. The governing equations and model implementation are presented and discussed, along with examples of injection simulations. References 1. Tiraferri, A.; Sethi, R. Enhanced transport of zerovalent iron nanoparticles in saturated porous media by guar gum. J Nanopart Res 2009, 11(3), 635-645. 2. Tiraferri, A.; Chen, K.L.; Sethi, R.; Elimelech, M. Reduced aggregation and sedimentation of zero-valent iron nanoparticles in the presence of guar gum. Journal of Colloid and Interface Science 2008, 324(1-2), 71-79. 3. Dalla Vecchia, E.; Luna, M.; Sethi, R. Transport in Porous Media of Highly Concentrated Iron Micro- and Nanoparticles in the Presence of Xanthan Gum. Environmental Science & Technology 2009, 43(23), 8942-8947. 4. Tosco, T.; Gastone, F.; Sethi, R. Guar gum solutions for improved delivery of iron particles in porous media (Part 2): iron transport tests and modelling in radial geometry. Journal of Contaminant Hydrology (submitted).

Multi-scale approach to the modeling of fission gas discharge during hypothetical loss-of-flow accident in gen-IV sodium fast reactor

DOE Office of Scientific and Technical Information (OSTI.GOV)

Behafarid, F.; Shaver, D. R.; Bolotnov, I. A.

The required technological and safety standards for future Gen IV Reactors can only be achieved if advanced simulation capabilities become available, which combine high performance computing with the necessary level of modeling detail and high accuracy of predictions. The purpose of this paper is to present new results of multi-scale three-dimensional (3D) simulations of the inter-related phenomena, which occur as a result of fuel element heat-up and cladding failure, including the injection of a jet of gaseous fission products into a partially blocked Sodium Fast Reactor (SFR) coolant channel, and gas/molten sodium transport along the coolant channels. The computational approachmore » to the analysis of the overall accident scenario is based on using two different inter-communicating computational multiphase fluid dynamics (CMFD) codes: a CFD code, PHASTA, and a RANS code, NPHASE-CMFD. Using the geometry and time history of cladding failure and the gas injection rate, direct numerical simulations (DNS), combined with the Level Set method, of two-phase turbulent flow have been performed by the PHASTA code. The model allows one to track the evolution of gas/liquid interfaces at a centimeter scale. The simulated phenomena include the formation and breakup of the jet of fission products injected into the liquid sodium coolant. The PHASTA outflow has been averaged over time to obtain mean phasic velocities and volumetric concentrations, as well as the liquid turbulent kinetic energy and turbulence dissipation rate, all of which have served as the input to the core-scale simulations using the NPHASE-CMFD code. A sliding window time averaging has been used to capture mean flow parameters for transient cases. The results presented in the paper include testing and validation of the proposed models, as well the predictions of fission-gas/liquid-sodium transport along a multi-rod fuel assembly of SFR during a partial loss-of-flow accident. (authors)« less

Fuel cell membrane hydration and fluid metering

DOEpatents

Jones, Daniel O.; Walsh, Michael M.

2003-01-01

A hydration system includes fuel cell fluid flow plate(s) and injection port(s). Each plate has flow channel(s) with respective inlet(s) for receiving respective portion(s) of a given stream of reactant fluid for a fuel cell. Each injection port injects a portion of liquid water directly into its respective flow channel. This serves to hydrate at least corresponding part(s) of a given membrane of the corresponding fuel cell(s). The hydration system may be augmented by a metering system including flow regulator(s). Each flow regulator meters an injecting at inlet(s) of each plate of respective portions of liquid into respective portion(s) of a given stream of fluid by corresponding injection port(s).

Fluid Flow Prediction with Development System Interwell Connectivity Influence

NASA Astrophysics Data System (ADS)

Bolshakov, M.; Deeva, T.; Pustovskikh, A.

2016-03-01

In this paper interwell connectivity has been studied. First of all, literature review of existing methods was made which is divided into three groups: Statistically-Based Methods, Material (fluid) Propagation-Based Methods and Potential (pressure) Change Propagation-Based Method. The disadvantages of the first and second groups are as follows: methods do not involve fluid flow through porous media, ignore any changes of well conditions (BHP, skin factor, etc.). The last group considers changes of well conditions and fluid flow through porous media. In this work Capacitance method (CM) has been chosen for research. This method is based on material balance and uses weight coefficients lambdas to assess well influence. In the next step synthetic model was created for examining CM. This model consists of an injection well and a production well. CM gave good results, it means that flow rates which were calculated by analytical method (CM) show matching with flow rate in model. Further new synthetic model was created which includes six production and one injection wells. This model represents seven-spot pattern. To obtain lambdas weight coefficients, the delta function was entered using by minimization algorithm. Also synthetic model which has three injectors and thirteen producer wells was created. This model simulates seven-spot pattern production system. Finally Capacitance method (CM) has been adjusted on real data of oil Field Ω. In this case CM does not give enough satisfying results in terms of field data liquid rate. In conclusion, recommendations to simplify CM calculations were given. Field Ω is assumed to have one injection and one production wells. In this case, satisfying results for production rates and cumulative production were obtained.

CFD-Based Design of a Filming Injector for N+3 Combustors

NASA Technical Reports Server (NTRS)

Ajmani, Kumud; Mongia, Hukam; Lee, Phil

2016-01-01

An effort was undertaken to perform CFD analysis of fluid flow in Lean-Direct Injection (LDI) combustors with axial swirl-venturi elements coupled with a new fuel-filming injector design for next-generation N+3 combustors. The National Combustion Code (NCC) was used to perform non-reacting and two-phase reacting flow computations on a N+3 injector configuration, in a single-element and a five-element injector array. All computations were performed with a consistent approach towards mesh-generation, spray-, ignition- and kinetics-modeling with the NCC. Computational predictions of the aerodynamics of the injector were used to arrive at an optimal injector design that met effective area, aerodynamics, and fuel-air mixing criteria. LDI-3 emissions (EINOx, EICO and UHC) were compared with the previous generation LDI-2 combustor experimental data at representative engine cycle conditions.

Special Course on Three-Dimensional Supersonic/Hypersonic Flows Including Separation

DTIC Science & Technology

1990-01-01

STAGE, AIRBREATHING VEHICLE. ALSO SHOWN ON THE FIGURE ARE TWO DATA POINTS FOR THE ACCELERATION OF THE X-15. THE X-15 WAS PROPELLED BY AIR NH3 - 02 ROCKET...FUEL IS INJECTED PARALLEL TO THE FLOW FROM THE BASE OF THE STRUTS AND MIXES AND REACTS SLOWLY WITH THE AIR . AS THE SPEED IS INCREASED, FUEL IS ALSO...INJECTED FROM THE SIDES OF THE STRUTS TO ACHIEVE MORE RAPID MIXING. AT THE HIGHEST SPEEDS, IT IS DESIRABLE TO HAVE THE FUEL AND AIR MIX AND REACT AS

Investigation of Thrust Augmentation of a 1600-pound Thrust Centrifugal-flow-type Turbojet Engine by Injection of Refrigerants at Compressor Inlets

NASA Technical Reports Server (NTRS)

Jones, William L.; Dowman, Harry W.

1947-01-01

Investigations were conducted to determine effectiveness of refrigerants in increasing thrust of turbojet engines. Mixtures of water an alcohol were injected for a range of total flows up to 2.2 lb/sec. Kerosene was injected into inlets covering a range of injected flows up to approximately 30% of normal engine fuel flow. Injection of 2.0 lb/sec of water alone produced an increase in thrust of 35.8% of rate engine conditions and kerosene produced a negligible increase in thrust. Carbon dioxide increased thrust 23.5 percent.

A multitracer system for multizone ventilation measurement

NASA Astrophysics Data System (ADS)

Sherman, Max

1990-09-01

Mass transfer due to pressure-driven air flow is one of the most important processes for determining both environmental quality and energy requirements in buildings. Heat, moisture, and contaminants are all transported by air movement between indoors and outdoors as well as between different zones within a building. Measurement of these air flows is critical to understanding the performance of buildings. Virtually all measurements of ventilation are made using the dilution of a tracer gas. The vast majority of such measurements have been made in a single zone, using a single tracer gas. For the past several years LBL has been developing the MultiTracer Measurement System (MTMS) to provide full multizone air flow information in an accurate, real-time manner. MTMS is based on a quadrupole mass spectrometer to provide high-speed concentration analysis of multiple tracer gases in the (low) ppm level that are injected into multiple zones using mass-flow controllers. The measurement and injection system is controlled by a PC and can measure all concentrations in all zones (and adjust the injected tracer flows) within 2 min and can operate unattended for weeks. The resulting injection rate and concentration data can be analyzed to infer the bulk air movement between zones. The system also measures related quantities such as weather and zonal temperature to assist in the data interpretation. Using MTMS, field measurements have been made for the past two years.

Vertically Integrated Models for Carbon Storage Modeling in Heterogeneous Domains

NASA Astrophysics Data System (ADS)

Bandilla, K.; Celia, M. A.

2017-12-01

Numerical modeling is an essential tool for studying the impacts of geologic carbon storage (GCS). Injection of carbon dioxide (CO2) into deep saline aquifers leads to multi-phase flow (injected CO2 and resident brine), which can be described by a set of three-dimensional governing equations, including mass-balance equation, volumetric flux equations (modified Darcy), and constitutive equations. This is the modeling approach on which commonly used reservoir simulators such as TOUGH2 are based. Due to the large density difference between CO2 and brine, GCS models can often be simplified by assuming buoyant segregation and integrating the three-dimensional governing equations in the vertical direction. The integration leads to a set of two-dimensional equations coupled with reconstruction operators for vertical profiles of saturation and pressure. Vertically-integrated approaches have been shown to give results of comparable quality as three-dimensional reservoir simulators when applied to realistic CO2 injection sites such as the upper sand wedge at the Sleipner site. However, vertically-integrated approaches usually rely on homogeneous properties over the thickness of a geologic layer. Here, we investigate the impact of general (vertical and horizontal) heterogeneity in intrinsic permeability, relative permeability functions, and capillary pressure functions. We consider formations involving complex fluvial deposition environments and compare the performance of vertically-integrated models to full three-dimensional models for a set of hypothetical test cases consisting of high permeability channels (streams) embedded in a low permeability background (floodplains). The domains are randomly generated assuming that stream channels can be represented by sinusoidal waves in the plan-view and by parabolas for the streams' cross-sections. Stream parameters such as width, thickness and wavelength are based on values found at the Ketzin site in Germany. Results from the vertically-integrated approach are compared to results using TOUGH2, both in terms of depth-averaged saturation and vertical saturation profiles.

Travel-time-based thermal tracer tomography

NASA Astrophysics Data System (ADS)

Somogyvári, Márk; Bayer, Peter; Brauchler, Ralf

2016-05-01

Active thermal tracer testing is a technique to get information about the flow and transport properties of an aquifer. In this paper we propose an innovative methodology using active thermal tracers in a tomographic setup to reconstruct cross-well hydraulic conductivity profiles. This is facilitated by assuming that the propagation of the injected thermal tracer is mainly controlled by advection. To reduce the effects of density and viscosity changes and thermal diffusion, early-time diagnostics are used and specific travel times of the tracer breakthrough curves are extracted. These travel times are inverted with an eikonal solver using the staggered grid method to reduce constraints from the pre-defined grid geometry and to improve the resolution. Finally, non-reliable pixels are removed from the derived hydraulic conductivity tomograms. The method is applied to successfully reconstruct cross-well profiles as well as a 3-D block of a high-resolution fluvio-aeolian aquifer analog data set. Sensitivity analysis reveals a negligible role of the injection temperature, but more attention has to be drawn to other technical parameters such as the injection rate. This is investigated in more detail through model-based testing using diverse hydraulic and thermal conditions in order to delineate the feasible range of applications for the new tomographic approach.

Glacial uplift: fluid injection beneath an elastic sheet on a poroelastic substrate

NASA Astrophysics Data System (ADS)

Neufeld, Jerome; Hewitt, Duncan; Chini, Greg

2016-11-01

Supraglacial lakes can drain to the base of glaciers extremely rapidly, causing localised uplift of the surrounding glacier and affecting its sliding velocity. The means by which large volumes of drained water interact with and leak into the subglacial hydrological system is unclear, as is the role of the basal till. A theoretical study of the spread of fluid injected below an elastic sheet (the ice) is presented, where the ice lies above, and initially compresses, a deformable poroelastic layer. As pressurized fluid is injected, the deformable layer swells to accommodate more fluid. If sufficient fluid is injected, a 'blister' of fluid forms above the layer, causing the overburden to lift off the base. The flow is controlled by the local pressure drop across the tip of this blister, which depends subtly on both the flow of fluid through the porous layer below the tip, and on poroelastic deformation in the till ahead of the tip. The spreading behaviour and dependence on key parameters is analysed. Predictions of the model are compared to field measurements of uplift from draining glacial lakes in Greenland.

Integrating a dual-silicon photoelectrochemical cell into a redox flow battery for unassisted photocharging

PubMed Central

Liao, Shichao; Zong, Xu; Seger, Brian; Pedersen, Thomas; Yao, Tingting; Ding, Chunmei; Shi, Jingying; Chen, Jian; Li, Can

2016-01-01

Solar rechargeable flow cells (SRFCs) provide an attractive approach for in situ capture and storage of intermittent solar energy via photoelectrochemical regeneration of discharged redox species for electricity generation. However, overall SFRC performance is restricted by inefficient photoelectrochemical reactions. Here we report an efficient SRFC based on a dual-silicon photoelectrochemical cell and a quinone/bromine redox flow battery for in situ solar energy conversion and storage. Using narrow bandgap silicon for efficient photon collection and fast redox couples for rapid interface charge injection, our device shows an optimal solar-to-chemical conversion efficiency of ∼5.9% and an overall photon–chemical–electricity energy conversion efficiency of ∼3.2%, which, to our knowledge, outperforms previously reported SRFCs. The proposed SRFC can be self-photocharged to 0.8 V and delivers a discharge capacity of 730 mAh l−1. Our work may guide future designs for highly efficient solar rechargeable devices. PMID:27142885

Drug delivery into the cochlear apex: Improved control to sequentially affect finely spaced regions along the entire length of the cochlear spiral.

PubMed

Lichtenhan, J T; Hartsock, J; Dornhoffer, J R; Donovan, K M; Salt, A N

2016-11-01

Administering pharmaceuticals to the scala tympani of the inner ear is a common approach to study cochlear physiology and mechanics. We present here a novel method for in vivo drug delivery in a controlled manner to sealed ears. Injections of ototoxic solutions were applied from a pipette sealed into a fenestra in the cochlear apex, progressively driving solutions along the length of scala tympani toward the cochlear aqueduct at the base. Drugs can be delivered rapidly or slowly. In this report we focus on slow delivery in which the injection rate is automatically adjusted to account for varying cross sectional area of the scala tympani, therefore driving a solution front at uniform rate. Objective measurements originating from finely spaced, low- to high-characteristic cochlear frequency places were sequentially affected. Comparison with existing methods(s): Controlled administration of pharmaceuticals into the cochlear apex overcomes a number of serious limitations of previously established methods such as cochlear perfusions with an injection pipette in the cochlear base: The drug concentration achieved is more precisely controlled, drug concentrations remain in scala tympani and are not rapidly washed out by cerebrospinal fluid flow, and the entire length of the cochlear spiral can be treated quickly or slowly with time. Controlled administration of solutions into the cochlear apex can be a powerful approach to sequentially effect objective measurements originating from finely spaced cochlear regions and allows, for the first time, the spatial origin of CAPs to be objectively defined. Copyright © 2016 Elsevier B.V. All rights reserved.

Drug delivery into the cochlear apex: Improved control to sequentially affect finely spaced regions along the entire length of the cochlear spiral

PubMed Central

Lichtenhan, JT; Hartsock, J; Dornhoffer, JR; Donovan, KM; Salt, AN

2016-01-01

Background Administering pharmaceuticals to the scala tympani of the inner ear is a common approach to study cochlear physiology and mechanics. We present here a novel method for in vivo drug delivery in a controlled manner to sealed ears. New method Injections of ototoxic solutions were applied from a pipette sealed into a fenestra in the cochlear apex, progressively driving solutions along the length of scala tympani toward the cochlear aqueduct at the base. Drugs can be delivered rapidly or slowly. In this report we focus on slow delivery in which the injection rate is automatically adjusted to account for varying cross sectional area of the scala tympani, therefore driving a solution front at uniform rate. Results Objective measurements originating from finely spaced, low- to high-characteristic cochlear frequency places were sequentially affected. Comparison with existing methods(s): Controlled administration of pharmaceuticals into the cochlear apex overcomes a number of serious limitations of previously established methods such as cochlear perfusions with an injection pipette in the cochlear base: The drug concentration achieved is more precisely controlled, drug concentrations remain in scala tympani and are not rapidly washed out by cerebrospinal fluid flow, and the entire length of the cochlear spiral can be treated quickly or slowly with time. Conclusions Controlled administration of solutions into the cochlear apex can be a powerful approach to sequentially effect objective measurements originating from finely spaced cochlear regions and allows, for the first time, the spatial origin of CAPs to be objectively defined. PMID:27506463

Ducted fuel injection: A new approach for lowering soot emissions from direct-injection engines

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mueller, Charles J.; Nilsen, Christopher W.; Ruth, Daniel J.

Designers of direct-injection compression-ignition engines use a variety of strategies to improve the fuel/charge-gas mixture within the combustion chamber for increased efficiency and reduced pollutant emissions. Strategies include the use of high fuel-injection pressures, multiple injections, small injector orifices, flow swirl, long-ignition-delay conditions, and oxygenated fuels. This is the first journal publication paper on a new mixing-enhancement strategy for emissions reduction: ducted fuel injection. The concept involves injecting fuel along the axis of a small cylindrical duct within the combustion chamber, to enhance the mixture in the autoignition zone relative to a conventional free-spray configuration (i.e., a fuel spray thatmore » is not surrounded by a duct). Finally, the results described herein, from initial proof-of-concept experiments conducted in a constant-volume combustion vessel, show dramatically lower soot incandescence from ducted fuel injection than from free sprays over a range of charge-gas conditions that are representative of those in modern direct-injection compression-ignition engines.« less

Ducted fuel injection: A new approach for lowering soot emissions from direct-injection engines

DOE PAGES

Mueller, Charles J.; Nilsen, Christopher W.; Ruth, Daniel J.; ...

2017-07-18

Designers of direct-injection compression-ignition engines use a variety of strategies to improve the fuel/charge-gas mixture within the combustion chamber for increased efficiency and reduced pollutant emissions. Strategies include the use of high fuel-injection pressures, multiple injections, small injector orifices, flow swirl, long-ignition-delay conditions, and oxygenated fuels. This is the first journal publication paper on a new mixing-enhancement strategy for emissions reduction: ducted fuel injection. The concept involves injecting fuel along the axis of a small cylindrical duct within the combustion chamber, to enhance the mixture in the autoignition zone relative to a conventional free-spray configuration (i.e., a fuel spray thatmore » is not surrounded by a duct). Finally, the results described herein, from initial proof-of-concept experiments conducted in a constant-volume combustion vessel, show dramatically lower soot incandescence from ducted fuel injection than from free sprays over a range of charge-gas conditions that are representative of those in modern direct-injection compression-ignition engines.« less

Solute plumes mean velocity in aquifer transport: Impact of injection and detection modes

NASA Astrophysics Data System (ADS)

Dagan, Gedeon

2017-08-01

Flow of mean velocity U takes place in a heterogeneous aquifer of random spatially variable conductivity K. A solute plume is injected instantaneously along a plane normal to U, over a large area relative to the logconductivity integral scale I (ergodic plume). Transport is by advection by the spatially variable Eulerian velocity. The study is focused on the derivation of the mean plume velocity in the four modes set forth by Kreft and Zuber [1978] for one dimensional flow in a homogeneous medium. In the resident injection mode the mass is initially distributed uniformly in space while in the flux mode it is proportional to the local velocity. In the resident detection mode the mean velocity pertains to the plume centroid, whereas in flux detection it is quantified with the aid of the BTC and the corresponding mean arrival time. In agreement with the literature, it is shown that URR and UFF, pertaining to same injection and detection modes, either resident or flux, are equal to U. In contrast, in the mixed modes the solute velocity may differ significantly from U near the injection plane, approaching it at large distances relative to I. These effects are explained qualitatively with the aid of the exact solution for stratified aquifers.

A microchip-based flow injection-amperometry system with mercaptopropionic acid modified electroless gold microelectrode for the selective determination of dopamine.

PubMed

Wang, Yi; Luo, Jie; Chen, Hengwu; He, Qiaohong; Gan, Nin; Li, Tianhua

2008-09-12

A novel chip-based flow injection analysis (FIA) system has been developed for automatic, rapid and selective determination of dopamine (DA) in the presence of ascorbic acid (AA). The system is composed of a polycarbonate (PC) microfluidic chip with an electrochemical detector (ED), a gravity pump, and an automatic sample loading and injection unit. The selectivity of the ED was improved by modification of the gold working microelectrode, which was fabricated on the PC chip by UV-directed electroless gold plating, with a self-assembled monolayer (SAM) of 3-mercaptopropionic acid (MPA). Postplating treatment methods for cleaning the surface of electroless gold microelectrodes were investigated to ensure the formation of high quality SAMs. The effects of detection potential, flow rate, and sampling volume on the performance of the chip-based FIA system were studied. Under optimum conditions, a detection limit of 74 nmol L(-1) for DA was achieved at the sample throughput rate of 180 h(-1). A RSD of 0.9% for peak heights was observed for 19 runs of a 100 micromol L(-1) DA solution. Interference-free determination of DA could be conducted if the concentration ratio of AA-DA was no more than 10.

Dual-phase gas-permeation flow-injection thermometric analysis for the determination of carbon dioxide.

PubMed

Liu, S J; Tubino, M

1998-11-01

A flow-injection configuration based on a dual-phase gas-permeation system from a liquid donor to a gas acceptor stream with a thermistor flow-through detector is proposed for the direct analysis of the gas in the acceptor. This system was applied for the determination of carbon dioxide (in the form of carbonate) using the following chemical reaction: CO(2)(g)+2NH(3)(g)+H(2)O(g)=(NH(4))(2)CO(3)(s), with a linear response from 1x10(-3) to 50x10(-3) mol l(-1) of CO(3)(2-). Carbon dioxide was produced in the liquid donor and permeated into the gaseous acceptor stream of air/water vapor. The detection limit is 1x10(-3) mol l(-1) of carbonate, and a sampling frequency of 60 h(-1) is achieved with a relative standard deviation of 4.1% for replicate injections. The dual-phase gas-permeation flow-injection manifold, along with the membrane and phase separations, as well as the chemical reaction, provides enhanced selectivity when compared with the system employing a liquid acceptor stream, as serious interferents in this system, for instance, acetate and formate, among others, do not interfere in the proposed system.

Estimation of the quantification uncertainty from flow injection and liquid chromatography transient signals in inductively coupled plasma mass spectrometry

NASA Astrophysics Data System (ADS)

Laborda, Francisco; Medrano, Jesús; Castillo, Juan R.

2004-06-01

The quality of the quantitative results obtained from transient signals in high-performance liquid chromatography-inductively coupled plasma mass spectrometry (HPLC-ICPMS) and flow injection-inductively coupled plasma mass spectrometry (FI-ICPMS) was investigated under multielement conditions. Quantification methods were based on multiple-point calibration by simple and weighted linear regression, and double-point calibration (measurement of the baseline and one standard). An uncertainty model, which includes the main sources of uncertainty from FI-ICPMS and HPLC-ICPMS (signal measurement, sample flow rate and injection volume), was developed to estimate peak area uncertainties and statistical weights used in weighted linear regression. The behaviour of the ICPMS instrument was characterized in order to be considered in the model, concluding that the instrument works as a concentration detector when it is used to monitorize transient signals from flow injection or chromatographic separations. Proper quantification by the three calibration methods was achieved when compared to reference materials, although the double-point calibration allowed to obtain results of the same quality as the multiple-point calibration, shortening the calibration time. Relative expanded uncertainties ranged from 10-20% for concentrations around the LOQ to 5% for concentrations higher than 100 times the LOQ.

Enhancing resolution of free-flow zone electrophoresis via a simple sheath-flow sample injection.

PubMed

Yang, Ying; Kong, Fan-Zhi; Liu, Ji; Li, Jun-Min; Liu, Xiao-Ping; Li, Guo-Qing; Wang, Ju-Fang; Xiao, Hua; Fan, Liu-Yin; Cao, Cheng-Xi; Li, Shan

2016-07-01

In this work, a simple and novel sheath-flow sample injection method (SFSIM) is introduced to reduce the band broadening of free-flow zone electrophoresis separation in newly developed self-balance free-flow electrophoresis instrument. A needle injector was placed in the center of the separation inlet, into which the BGE and sample solution were pumped simultaneously. BGE formed sheath flow outside the sample stream, resulting in less band broadening related to hydrodynamics and electrodynamics. Hemoglobin and C-phycocyanin were successfully separated by the proposed method in contrast to the poor separation of free-flow electrophoresis with the traditional injection method without sheath flow. About 3.75 times resolution enhancement could be achieved by sheath-flow sample injection method. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

A LabVIEW®-based software for the control of the AUTORAD platform: a fully automated multisequential flow injection analysis Lab-on-Valve (MSFIA-LOV) system for radiochemical analysis.

PubMed

Barbesi, Donato; Vicente Vilas, Víctor; Millet, Sylvain; Sandow, Miguel; Colle, Jean-Yves; Aldave de Las Heras, Laura

2017-01-01

A LabVIEW ® -based software for the control of the fully automated multi-sequential flow injection analysis Lab-on-Valve (MSFIA-LOV) platform AutoRAD performing radiochemical analysis is described. The analytical platform interfaces an Arduino ® -based device triggering multiple detectors providing a flexible and fit for purpose choice of detection systems. The different analytical devices are interfaced to the PC running LabVIEW ® VI software using USB and RS232 interfaces, both for sending commands and receiving confirmation or error responses. The AUTORAD platform has been successfully applied for the chemical separation and determination of Sr, an important fission product pertinent to nuclear waste.

A Semi-Analytical Method for Rapid Estimation of Near-Well Saturation, Temperature, Pressure and Stress in Non-Isothermal CO2 Injection

NASA Astrophysics Data System (ADS)

LaForce, T.; Ennis-King, J.; Paterson, L.

2015-12-01

Reservoir cooling near the wellbore is expected when fluids are injected into a reservoir or aquifer in CO2 storage, enhanced oil or gas recovery, enhanced geothermal systems, and water injection for disposal. Ignoring thermal effects near the well can lead to under-prediction of changes in reservoir pressure and stress due to competition between increased pressure and contraction of the rock in the cooled near-well region. In this work a previously developed semi-analytical model for immiscible, nonisothermal fluid injection is generalised to include partitioning of components between two phases. Advection-dominated radial flow is assumed so that the coupled two-phase flow and thermal conservation laws can be solved analytically. The temperature and saturation profiles are used to find the increase in reservoir pressure, tangential, and radial stress near the wellbore in a semi-analytical, forward-coupled model. Saturation, temperature, pressure, and stress profiles are found for parameters representative of several CO2 storage demonstration projects around the world. General results on maximum injection rates vs depth for common reservoir parameters are also presented. Prior to drilling an injection well there is often little information about the properties that will determine the injection rate that can be achieved without exceeding fracture pressure, yet injection rate and pressure are key parameters in well design and placement decisions. Analytical solutions to simplified models such as these can quickly provide order of magnitude estimates for flow and stress near the well based on a range of likely parameters.

Effects of drop acceleration and deceleration on particle capture in a cross-flow gravity tower at intermediate drop Reynolds numbers.

PubMed

Kumar, Anoop; Gupta, S K; Kale, S R

2007-04-01

Cross-flow gravity towers are particle scrubbing devices in which water is sprayed from the top into particle-laden flow moving horizontally. Models for predicting particle capture assume drops traveling at terminal velocity and potential flow (ReD > 1000) around it, however, Reynolds numbers in the intermediate range of 1 to 1000 are common in gravity towers. Drops are usually injected at velocities greater than their terminal velocities (as in nozzles) or from near rest (perforated tray) and they accelerate/decelerate to their terminal velocity in the tower. Also, the effects of intermediate drop Reynolds number on capture efficiency have been simulated for (a) drops at their terminal velocity and (b) drops accelerating/decelerating to their terminal velocity. Tower efficiency based on potential flow about the drop is 40%-50% greater than for 200 mm drops traveling at their terminal velocity. The corresponding values for 500 mm drops are about 10%-20%. The drop injection velocity is important operating parameter. Increase in tower efficiency by about 40% for particles smaller than 5 mm is observed for increase in injection velocity from 0 to 20 m/s for 200 and 500mm drops.

Biosensing of glucose in flow injection analysis system based on glucose oxidase-quantum dot modified pencil graphite electrode.

PubMed

Sağlam, Özlem; Kızılkaya, Bayram; Uysal, Hüseyin; Dilgin, Yusuf

2016-01-15

A novel amperometric glucose biosensor was proposed in flow injection analysis (FIA) system using glucose oxidase (GOD) and Quantum dot (ZnS-CdS) modified Pencil Graphite Electrode (PGE). After ZnS-CdS film was electrochemically deposited onto PGE surface, GOD was immobilized on the surface of ZnS-CdS/PGE through crosslinking with chitosan (CT). A pair of well-defined reversible redox peak of GOD was observed at GOD/CT/ZnS-CdS/PGE based on enzyme electrode by direct electron transfer between the protein and electrode. Further, obtained GOD/CT/ZnS-CdS/PGE offers a disposable, low cost, selective and sensitive electrochemical biosensing of glucose in FIA system based on the decrease of the electrocatalytic response of the reduced form of GOD to dissolved oxygen. Under optimum conditions (flow rate, 1.3mL min(-1); transmission tubing length, 10cm; injection volume, 100μL; and constant applied potential, -500mV vs. Ag/AgCl), the proposed method displayed a linear response to glucose in the range of 0.01-1.0mM with detection limit of 3.0µM. The results obtained from this study would provide the basis for further development of the biosensing using PGE based FIA systems. Copyright © 2015 Elsevier B.V. All rights reserved.

Combined Falling Drop/Open Port Sampling Interface System for Automated Flow Injection Mass Spectrometry

DOE PAGES

Van Berkel, Gary J.; Kertesz, Vilmos; Orcutt, Matt; ...

2017-11-07

The aim of this work was to demonstrate and to evaluate the analytical performance of a combined falling drop/open port sampling interface (OPSI) system as a simple noncontact, no-carryover, automated system for flow injection analysis with mass spectrometry. The falling sample drops were introduced into the OPSI using a widely available autosampler platform utilizing low cost disposable pipet tips and conventional disposable microtiter well plates. The volume of the drops that fell onto the OPSI was in the 7–15 μL range with an injected sample volume of several hundred nanoliters. Sample drop height, positioning of the internal capillary on themore » sampling end of the probe, and carrier solvent flow rate were optimized for maximum signal. Sample throughput, signal reproducibility, matrix effects, and quantitative analysis capability of the system were established using the drug molecule propranolol and its isotope labeled internal standard in water, unprocessed river water and two commercially available buffer matrices. A sample-to-sample throughput of ~45 s with a ~4.5 s base-to-base flow injection peak profile was obtained in these experiments. In addition, quantitation with minimally processed rat plasma samples was demonstrated with three different statin drugs (atorvastatin, rosuvastatin, and fluvastatin). Direct characterization capability of unprocessed samples was demonstrated by the analysis of neat vegetable oils. Employing the autosampler system for spatially resolved liquid extraction surface sampling exemplified by the analysis of propranolol and its hydroxypropranolol glucuronide phase II metabolites from a rat thin tissue section was also illustrated.« less

Combined Falling Drop/Open Port Sampling Interface System for Automated Flow Injection Mass Spectrometry

DOE Office of Scientific and Technical Information (OSTI.GOV)

Van Berkel, Gary J.; Kertesz, Vilmos; Orcutt, Matt

The aim of this work was to demonstrate and to evaluate the analytical performance of a combined falling drop/open port sampling interface (OPSI) system as a simple noncontact, no-carryover, automated system for flow injection analysis with mass spectrometry. The falling sample drops were introduced into the OPSI using a widely available autosampler platform utilizing low cost disposable pipet tips and conventional disposable microtiter well plates. The volume of the drops that fell onto the OPSI was in the 7–15 μL range with an injected sample volume of several hundred nanoliters. Sample drop height, positioning of the internal capillary on themore » sampling end of the probe, and carrier solvent flow rate were optimized for maximum signal. Sample throughput, signal reproducibility, matrix effects, and quantitative analysis capability of the system were established using the drug molecule propranolol and its isotope labeled internal standard in water, unprocessed river water and two commercially available buffer matrices. A sample-to-sample throughput of ~45 s with a ~4.5 s base-to-base flow injection peak profile was obtained in these experiments. In addition, quantitation with minimally processed rat plasma samples was demonstrated with three different statin drugs (atorvastatin, rosuvastatin, and fluvastatin). Direct characterization capability of unprocessed samples was demonstrated by the analysis of neat vegetable oils. Employing the autosampler system for spatially resolved liquid extraction surface sampling exemplified by the analysis of propranolol and its hydroxypropranolol glucuronide phase II metabolites from a rat thin tissue section was also illustrated.« less

Sample stacking of fast-moving anions in capillary zone electrophoresis with pH-suppressed electroosmotic flow.

PubMed

Quirino, J P; Terabe, S

1999-07-30

On-line sample concentration of fast moving inorganic anions by large volume sample stacking (LVSS) and field enhanced sample injection (FESI) with a water plug under acidic conditions is presented. Detection sensitivity enhancements were around 100 and 1000-fold for LVSS and FESI, respectively. However, reproducibility and linearity of response in the LVSS approach is superior compared to the FESI approach.

The Relative Influence of Turbulence and Turbulent Mixing on the Adsorption of Mercury within a Gas-Sorbent Suspension

EPA Science Inventory

Our previous investigations demonstrated that entrained flow or in-flight adsorption can be a more effective and flexible approach to trace gas adsorption than fixed sorbent beds. The present investigation establishes the turbulent mixing that accompanies sorbent injection is an ...

Hydrologic and geomorphic controls on hyporheic exchange during base flow recession in a headwater mountain stream

Treesearch

A.S. Ward; M. Fitzgerald; M.N. Gooseff; A.M. Binley; K. Singha

2012-01-01

Hyporheic hydrodynamics are a control on stream ecosystems, yet we lack a thorough understanding of catchment controls on these flow paths, including valley constraint and hydraulic gradients in the valley bottom. We performed four whole-stream solute tracer injections under steady state flow conditions at the H. J. Andrews Experimental Forest (Oregon, United States)...

Understanding leachate flow in municipal solid waste landfills by combining time-lapse ERT and subsurface flow modelling - Part II: Constraint methodology of hydrodynamic models.

PubMed

Audebert, M; Oxarango, L; Duquennoi, C; Touze-Foltz, N; Forquet, N; Clément, R

2016-09-01

Leachate recirculation is a key process in the operation of municipal solid waste landfills as bioreactors. To ensure optimal water content distribution, bioreactor operators need tools to design leachate injection systems. Prediction of leachate flow by subsurface flow modelling could provide useful information for the design of such systems. However, hydrodynamic models require additional data to constrain them and to assess hydrodynamic parameters. Electrical resistivity tomography (ERT) is a suitable method to study leachate infiltration at the landfill scale. It can provide spatially distributed information which is useful for constraining hydrodynamic models. However, this geophysical method does not allow ERT users to directly measure water content in waste. The MICS (multiple inversions and clustering strategy) methodology was proposed to delineate the infiltration area precisely during time-lapse ERT survey in order to avoid the use of empirical petrophysical relationships, which are not adapted to a heterogeneous medium such as waste. The infiltration shapes and hydrodynamic information extracted with MICS were used to constrain hydrodynamic models in assessing parameters. The constraint methodology developed in this paper was tested on two hydrodynamic models: an equilibrium model where, flow within the waste medium is estimated using a single continuum approach and a non-equilibrium model where flow is estimated using a dual continuum approach. The latter represents leachate flows into fractures. Finally, this methodology provides insight to identify the advantages and limitations of hydrodynamic models. Furthermore, we suggest an explanation for the large volume detected by MICS when a small volume of leachate is injected. Copyright © 2016 Elsevier Ltd. All rights reserved.

Reducing Risk in CO2 Sequestration: A Framework for Integrated Monitoring of Basin Scale Injection

NASA Astrophysics Data System (ADS)

Seto, C. J.; Haidari, A. S.; McRae, G. J.

2009-12-01

Geological sequestration of CO2 is an option for stabilization of atmospheric CO2 concentrations. Technical ability to safely store CO2 in the subsurface has been demonstrated through pilot projects and a long history of enhanced oil recovery and acid gas disposal operations. To address climate change, current injection operations must be scaled up by a factor of 100, raising issues of safety and security. Monitoring and verification is an essential component in ensuring safe operations and managing risk. Monitoring provides assurance that CO2 is securely stored in the subsurface, and the mechanisms governing transport and storage are well understood. It also provides an early warning mechanism for identification of anomalies in performance, and a means for intervention and remediation through the ability to locate the CO2. Through theoretical studies, bench scale experiments and pilot tests, a number of technologies have demonstrated their ability to monitor CO2 in the surface and subsurface. Because the focus of these studies has been to demonstrate feasibility, individual techniques have not been integrated to provide a more robust method for monitoring. Considering the large volumes required for injection, size of the potential footprint, length of time a project must be monitored and uncertainty, operational considerations of cost and risk must balance safety and security. Integration of multiple monitoring techniques will reduce uncertainty in monitoring injected CO2, thereby reducing risk. We present a framework for risk management of large scale injection through model based monitoring network design. This framework is applied to monitoring CO2 in a synthetic reservoir where there is uncertainty in the underlying permeability field controlling fluid migration. Deformation and seismic data are used to track plume migration. A modified Ensemble Kalman filter approach is used to estimate flow properties by jointly assimilating flow and geomechanical observations. Issues of risk, cost and uncertainty are considered.

Active Flow Control and Global Stability Analysis of Separated Flow Over a NACA 0012 Airfoil

NASA Astrophysics Data System (ADS)

Munday, Phillip M.

The objective of this computational study is to examine and quantify the influence of fundamental flow control inputs in suppressing flow separation over a canonical airfoil. Most flow control studies to this date have relied on the development of actuator technology, and described the control input based on specific actuators. Taking advantage of a computational framework, we generalize the inputs to fundamental perturbations without restricting inputs to a particular actuator. Utilizing this viewpoint, generalized control inputs aim to aid in the quantification and support the design of separation control techniques. This study in particular independently introduces wall-normal momentum and angular momentum to the separated flow using swirling jets through model boundary conditions. The response of the flow field and the surface vorticity fluxes to various combinations of actuation inputs are examined in detail. By closely studying different variables, the influence of the wall-normal and angular momentum injections on separated flow is identified. As an example, open-loop control of fully separated, incompressible flow over a NACA 0012 airfoil at alpha = 6° and 9° with Re = 23,000 is examined with large-eddy simulations. For the shallow angle of attack alpha = 6°, the small recirculation region is primarily affected by wall-normal momentum injection. For a larger separation region at alpha = 9°, it is observed that the addition of angular momentum input to wall-normal momentum injection enhances the suppression of flow separation. Reducing the size of the separated flow region significantly impacts the forces, and in particular reduces drag and increases lift on the airfoil. It was found that the influence of flow control on the small recirculation region (alpha = 6°) can be sufficiently quantified with the traditional coefficient of momentum. At alpha = 9°, the effects of wall-normal and angular momentum inputs are captured by modifying the standard definition of the coefficient of momentum, which successfully characterizes suppression of separation and lift enhancement. The effect of angular momentum is incorporated into the modified coefficient of momentum by introducing a characteristic swirling jet velocity based on the non-dimensional swirl number. With the modified coefficient of momentum, this single value is able to categorize controlled flows into separated, transitional, and attached flows. With inadequate control input (separated flow regime), lift decreased compared to the baseline flow. Increasing the modified coefficient of momentum, flow transitions from separated to attached and accordingly results in improved aerodynamic forces. Modifying the spanwise spacing, it is shown that the minimum modified coefficient of momentum input required to begin transitioning the flow is dependent on actuator spacing. The growth (or decay) of perturbations can facilitate or inhibit the influence of flow control inputs. Biglobal stability analysis is considered to further analyze the behavior of control inputs on separated flow over a symmetric airfoil. Assuming a spanwise periodic waveform for the perturbations, the eigenvalues and eigenvectors about a base flow are solved to understand the influence of spanwise variation on the development of the flow. Two algorithms are developed and validated to solve for the eigenvalues of the flow: an algebraic eigenvalue solver (matrix based) and a time-stepping algorithm. The matrix based approach is formulated without ever storing the matrices, creating a computationally memory efficient algorithm. Increasing the Reynolds number to Re = 23,000 over a NACA 0012 airfoil, the time-stepper method is implemented due to rising computational cost of the matrix-based method. Stability analysis about the time-averaged flow is performed for spanwise wavenumbers of beta = 1/c, 10pi/ c and 20pi/c, which the latter two wavenumbers are representative of the spanwise spacing between the actuators. The largest spanwise wavelength (beta = 1/c) contained unstable modes that ranged from low to high frequency, and a particular unstable low-frequency mode corresponding to a frequency observed in the lift forces of the baseline large-eddy simulation. For the larger spanwise wavenumbers, beta = 10pi/ c (Lz/c = 0.2) and 20pi/c (Lz/c = 0.1), low-frequency modes were damped and only modes with f > 5were unstable. These results help us gain further insight into the influence of the flow control inputs. In conclusion, it was shown that the influence of wall-normal and angular momentum inputs on fully separated flow can adequately be described by the modified coefficient of momentum. Through further analysis and the development of a biglobal stability solver, spanwise spacing effects observed in the flow control study can be explained. The findings from this study should aid in the development of more intelligently designed flow control strategies and provide guidance in the selection of flow control actuators.

New diesel injection nozzle flow measuring device

NASA Astrophysics Data System (ADS)

Marčič, Milan

2000-04-01

A new measuring device has been developed for diesel injection nozzle testing, allowing measuring of the steady flow through injection nozzle and the injection rate. It can be best applied for measuring the low and high injection rates of the pintle and single hole nozzle. In steady flow measuring the fuel pressure at the inlet of the injection nozzle is 400 bar. The sensor of the measuring device measures the fuel charge, resulting from fuel rubbing in the fuel injection system, as well as from the temperature gradient in the sensor electrode. The electric charge is led to the charge amplifier, where it is converted into electric current and amplified. The amplifier can be used also to measure the mean injection rate value.

Static Flow Characteristics of a Mass Flow Injecting Valve

NASA Technical Reports Server (NTRS)

Mattern, Duane; Paxson, Dan

1995-01-01

A sleeve valve is under development for ground-based forced response testing of air compression systems. This valve will be used to inject air and to impart momentum to the flow inside the first stage of a multi-stage compressor. The valve was designed to deliver a maximum mass flow of 0.22 lbm/s (0.1 kg/s) with a maximum valve throat area of 0.12 sq. in (80 sq. mm), a 100 psid (689 KPA) pressure difference across the valve and a 68 F, (20 C) air supply. It was assumed that the valve mass flow rate would be proportional to the valve orifice area. A static flow calibration revealed a nonlinear valve orifice area to mass flow relationship which limits the maximum flow rate that the valve can deliver. This nonlinearity was found to be caused by multiple choking points in the flow path. A simple model was used to explain this nonlinearity and the model was compared to the static flow calibration data. Only steady flow data is presented here. In this report, the static flow characteristics of a proportionally controlled sleeve valve are modelled and validated against experimental data.

Coupled reservoir-geomechanical analysis of CO2 injection and ground deformations at In Salah, Algeria

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rutqvist, J.; Vasco, D.W.; Myer, L.

2009-11-01

In Salah Gas Project in Algeria has been injecting 0.5-1 million tonnes CO{sub 2} per year over the past five years into a water-filled strata at a depth of about 1,800 to 1,900 m. Unlike most CO{sub 2} storage sites, the permeability of the storage formation is relatively low and comparatively thin with a thickness of about 20 m. To ensure adequate CO{sub 2} flow-rates across the low-permeability sand-face, the In Salah Gas Project decided to use long-reach (about 1 to 1.5 km) horizontal injection wells. In an ongoing research project we use field data and coupled reservoir-geomechanical numerical modelingmore » to assess the effectiveness of this approach and to investigate monitoring techniques to evaluate the performance of a CO{sub 2}-injection operation in relatively low permeability formations. Among the field data used are ground surface deformations evaluated from recently acquired satellite-based inferrometry (InSAR). The InSAR data shows a surface uplift on the order of 5 mm per year above active CO{sub 2} injection wells and the uplift pattern extends several km from the injection wells. In this paper we use the observed surface uplift to constrain our coupled reservoir-geomechanical model and conduct sensitivity studies to investigate potential causes and mechanisms of the observed uplift. The results of our analysis indicates that most of the observed uplift magnitude can be explained by pressure-induced, poro-elastic expansion of the 20 m thick injection zone, but there could also be a significant contribution from pressure-induced deformations within a 100 m thick zone of shaly sands immediately above the injection zone.« less

Suppression of tritium retention in remote areas of ITER by nonperturbative reactive gas injection.

PubMed

Tabarés, F L; Ferreira, J A; Ramos, A; van Rooij, G; Westerhout, J; Al, R; Rapp, J; Drenik, A; Mozetic, M

2010-10-22

A technique based on reactive gas injection in the afterglow region of the divertor plasma is proposed for the suppression of tritium-carbon codeposits in remote areas of ITER when operated with carbon-based divertor targets. Experiments in a divertor simulator plasma device indicate that a 4  nm/min deposition can be suppressed by addition of 1  Pa·m³ s⁻¹ ammonia flow at 10 cm from the plasma. These results bolster the concept of nonperturbative scavenger injection for tritium inventory control in carbon-based fusion plasma devices, thus paving the way for ITER operation in the active phase under a carbon-dominated, plasma facing component background.

CFD Based Design of a Filming Injector for N+3 Combustors

NASA Technical Reports Server (NTRS)

Ajmani, Kumud; Mongia, Hukam; Lee, Phil

2016-01-01

An effort was undertaken to perform CFD analysis of fluid flow in Lean-Direct Injection (LDI) combustors with axial swirl-venturi elements for next-generation LDI-3 combustor design. The National Combustion Code (NCC) was used to perform non-reacting and two-phase reacting flow computations for a newly-designed pre-filming type fuel injector LDI-3 injector, in a single-injector and a five-injector array configuration. All computations were performed with a consistent approach of mesh-optimization, spray-modeling, ignition and kinetics-modeling. Computational predictions of the aerodynamics of the single-injector were used to arrive at an optimized main-injector design that meets effective area and fuel-air mixing criteria. Emissions (EINOx) characteristics were predicted for a medium-power engine cycle condition, and will be compared with data when it is made available from experimental measurements. The use of a PDF-like turbulence-chemistry interaction model with NCC's Time-Filtered Navier-Stokes (TFNS) solver is shown to produce a significant impact on the CFD results, when compared with a laminar-chemistry TFNS approach for the five-injector computations.

Flow monitoring and control system for injection wells

DOEpatents

Corey, John C.

1993-01-01

A system for monitoring and controlling the injection rate of fluid by an injection well of an in-situ remediation system for treating a contaminated groundwater plume. The well is fitted with a gated insert, substantially coaxial with the injection well. A plurality of openings, some or all of which are equipped with fluid flow sensors and gates, are spaced along the insert. The gates and sensors are connected to a surface controller. The insert may extend throughout part of, or substantially the entire length of the injection well. Alternatively, the insert may comprise one or more movable modules which can be positioned wherever desired along the well. The gates are opened part-way at the start of treatment. The sensors monitor and display the flow rate of fluid passing through each opening on a controller. As treatment continues, the gates are opened to increase flow in regions of lesser flow, and closed to decrease flow in regions of greater flow, thereby approximately equalizing the amount of fluid reaching each part of the plume.

Flow monitoring and control system for injection wells

DOEpatents

Corey, J.C.

1993-02-16

A system for monitoring and controlling the injection rate of fluid by an injection well of an in-situ remediation system for treating a contaminated groundwater plume. The well is fitted with a gated insert, substantially coaxial with the injection well. A plurality of openings, some or all of which are equipped with fluid flow sensors and gates, are spaced along the insert. The gates and sensors are connected to a surface controller. The insert may extend throughout part of, or substantially the entire length of the injection well. Alternatively, the insert may comprise one or more movable modules which can be positioned wherever desired along the well. The gates are opened part-way at the start of treatment. The sensors monitor and display the flow rate of fluid passing through each opening on a controller. As treatment continues, the gates are opened to increase flow in regions of lesser flow, and closed to decrease flow in regions of greater flow, thereby approximately equalizing the amount of fluid reaching each part of the plume.

An experimental study of wall-injected flows in a rectangular cylinder

NASA Astrophysics Data System (ADS)

Perrotta, A.; Romano, G. P.; Favini, B.

2018-01-01

An experimental investigation of the flow inside a rectangular cylinder with air injected continuously along the wall is performed. This kind of flow is a two-dimensional approximation of what happens inside a solid rocket motor, where the lateral grain burns expelling exhaust gas or in processes with air filtration or devices to attain uniform flows. We propose a brief derivation of some analytical solutions and a comparison between these solutions and experimental data, which are obtained using the particle image velocimetry technique, to provide a global reconstruction of the flowfield. The flow, which enters orthogonal to the injecting wall, turns suddenly its direction being pushed towards the exit of the chamber. Under the incompressible and inviscid flow hypothesis, two analytical solutions are reported and compared. The first one, known as Hart-McClure solution, is irrotational and the injection velocity is non-perpendicular to the injecting wall. The other one, due to Taylor and Culick, has non-zero vorticity and constant, vertical injection velocity. The comparison with laminar solutions is useful to assess whether transition to turbulence is reached and how the disturbance thrown in by the porous injection influences and modifies those solutions.

Mathematical Model of Two Phase Flow in Natural Draft Wet-Cooling Tower Including Flue Gas Injection

NASA Astrophysics Data System (ADS)

Hyhlík, Tomáš

2016-03-01

The previously developed model of natural draft wet-cooling tower flow, heat and mass transfer is extended to be able to take into account the flow of supersaturated moist air. The two phase flow model is based on void fraction of gas phase which is included in the governing equations. Homogeneous equilibrium model, where the two phases are well mixed and have the same velocity, is used. The effect of flue gas injection is included into the developed mathematical model by using source terms in governing equations and by using momentum flux coefficient and kinetic energy flux coefficient. Heat and mass transfer in the fill zone is described by the system of ordinary differential equations, where the mass transfer is represented by measured fill Merkel number and heat transfer is calculated using prescribed Lewis factor.

Direct push injection logging for high resolution characterization of low permeability zones

NASA Astrophysics Data System (ADS)

Liu, G.; Knobbe, S.; Butler, J. J., Jr.; Reboulet, E. C.; Borden, R. C.; Bohling, G.

2017-12-01

One of the grand challenges for groundwater protection and contaminated site remediation efforts is dealing with the slow, yet persistent, release of contaminants from low permeability zones. In zones of higher permeability, groundwater flow is relatively fast and contaminant transport can be more effectively affected by treatment activities. In the low permeability zones, however, groundwater flow and contaminant transport are slow and thus become largely insensitive to many in-situ treatment efforts. Clearly, for sites with low permeability zones, accurate depiction of the mass exchange between the low and higher permeability zones is critical for designing successful groundwater protection and remediation systems, which requires certain information such as the hydraulic conductivity (K) and porosity of the subsurface. The current generation of field methods is primarily developed for relatively permeable zones, and little work has been undertaken for characterizing zones of low permeability. For example, the direct push injection logging (DPIL) approach (e.g., Hydraulic Profiling Tool by Geoprobe) is commonly used for high resolution estimation of K over a range of 0.03 to 23 m/d. When K is below 0.03 m/d, the pressure responses from the current DPIL are generally too high for both the formation (potential formation alteration at high pressure) and measuring device (pressure exceeding the upper sensor limit). In this work, we modified the current DPIL tool by adding a low-flow pump and flowmeter so that injection logging can be performed with much reduced flow rates when K is low. Numerical simulations showed that the reduction in injection rates (reduced from 250 to 1 mL/min) allowed pressures to be measurable even when K was as low as 0.001 m/d. They also indicated that as the K decreased, the pore water pressure increase induced by probe advancement had a more significant impact on DPIL results. A new field DPIL profiling procedure was developed for reducing that impact. Our preliminary test results in both the lab and at a field site have demonstrated the promise of the modified DPIL approach as a practical method for characterizing low permeability zones.

The impact of injector-based contrast agent administration in time-resolved MRA.

PubMed

Budjan, Johannes; Attenberger, Ulrike I; Schoenberg, Stefan O; Pietsch, Hubertus; Jost, Gregor

2018-05-01

Time-resolved contrast-enhanced MR angiography (4D-MRA), which allows the simultaneous visualization of the vasculature and blood-flow dynamics, is widely used in clinical routine. In this study, the impact of two different contrast agent injection methods on 4D-MRA was examined in a controlled, standardized setting in an animal model. Six anesthetized Goettingen minipigs underwent two identical 4D-MRA examinations at 1.5 T in a single session. The contrast agent (0.1 mmol/kg body weight gadobutrol, followed by 20 ml saline) was injected using either manual injection or an automated injection system. A quantitative comparison of vascular signal enhancement and quantitative renal perfusion analyses were performed. Analysis of signal enhancement revealed higher peak enhancements and shorter time to peak intervals for the automated injection. Significantly different bolus shapes were found: automated injection resulted in a compact first-pass bolus shape clearly separated from the recirculation while manual injection resulted in a disrupted first-pass bolus with two peaks. In the quantitative perfusion analyses, statistically significant differences in plasma flow values were found between the injection methods. The results of both qualitative and quantitative 4D-MRA depend on the contrast agent injection method, with automated injection providing more defined bolus shapes and more standardized examination protocols. • Automated and manual contrast agent injection result in different bolus shapes in 4D-MRA. • Manual injection results in an undefined and interrupted bolus with two peaks. • Automated injection provides more defined bolus shapes. • Automated injection can lead to more standardized examination protocols.

Chemical Analysis through CL-Detection Assisted by Periodate Oxidation

PubMed Central

Evmiridis, Nicholaos P.; Vlessidis, Athanasios G.; Thanasoulias, Nicholas C.

2007-01-01

The progress of the research work of the author and his colleagues on the field of CL-emission generated by pyrogallol oxidation and further application for the direct determination of periodate and indirect or direct determination of other compounds through flow-injection manifold/CL-detection set up is described. The instrumentation used for these studies was a simple flow-injection manifold that provides good reproducibility, coupled to a red sensitive photomultiplier that gives sensitive CL-detection. In addition, recent reports on studies and analytical methods based on CL-emission generated by periodate oxidation by other authors are included. PMID:17611611

Optimal contant time injection policy for enhanced oil recovery and characterization of optimal viscous profiles

NASA Astrophysics Data System (ADS)

Daripa, Prabir

2011-11-01

We numerically investigate the optimal viscous profile in constant time injection policy of enhanced oil recovery. In particular, we investigate the effect of a combination of interfacial and layer instabilities in three-layer porous media flow on the overall growth of instabilities and thereby characterize the optimal viscous profile. Results based on monotonic and non-monotonic viscous profiles will be presented. Time permitting. we will also present results on multi-layer porous media flows for Newtonian and non-Newtonian fluids and compare the results. The support of Qatar National Fund under a QNRF Grant is acknowledged.

An Integrated Approach on Groundwater Flow and Heat/Solute Transport for Sustainable Groundwater Source Heat Pump (GWHP) System Operation

NASA Astrophysics Data System (ADS)

Park, D. K.; Bae, G. O.; Joun, W.; Park, B. H.; Park, J.; Park, I.; Lee, K. K.

2015-12-01

The GWHP system uses a stable temperature of groundwater for cooling and heating in buildings and thus has been known as one of the most energy-saving and cost-efficient renewable energy techniques. A GWHP facility was installed at an island located at the confluence of North Han and South Han rivers, Korea. Because of well-developed alluvium, the aquifer is suitable for application of this system, extracting and injecting a large amount of groundwater. However, the numerical experiments under various operational conditions showed that it could be vulnerable to thermal interference due to the highly permeable gravel layer, as a preferential path of thermal plume migration, and limited space for well installation. Thus, regional groundwater flow must be an important factor of consideration for the efficient operation under these conditions but was found to be not simple in this site. While the groundwater level in this site totally depends on the river stage control of Paldang dam, the direction and velocity of the regional groundwater flow, observed using the colloidal borescope, have been changed hour by hour with the combined flows of both the rivers. During the pumping and injection tests, the water discharges in Cheongpyeong dam affected their respective results. Moreover, the measured NO3-N concentrations might imply the effect of agricultural activities around the facility on the groundwater quality along the regional flow. It is obvious that the extraction and injection of groundwater during the facility operation will affect the fate of the agricultural contaminants. Particularly, the gravel layer must also be a main path for contaminant migration. The simulations for contaminant transport during the facility operation showed that the operation strategy for only thermal efficiency could be unsafe and unstable in respect of groundwater quality. All these results concluded that the integrated approach on groundwater flow and heat/solute transport is necessary for the sustainable GWHP system operation. Acknowledgment: This work was supported by the research project of "Advanced Technology for Groundwater Development and Application in Riversides (Geowater+)" in "Water Resources Management Program (code 11 Technology Innovation C05)" of the MOLIT and the KAIA in Korea.

Investigation of Multiphase Flow in a Packed Bed Reactor Under Microgravity Conditions

NASA Technical Reports Server (NTRS)

Lian, Yongsheng; Motil, Brian; Rame, Enrique

2016-01-01

In this paper we study the two-phase flow phenomena in a packed bed reactor using an integrated experimental and numerical method. The cylindrical bed is filled with uniformly sized spheres. In the experiment water and air are injected into the bed simultaneously. The pressure distribution along the bed will be measured. The numerical simulation is based on a two-phase flow solver which solves the Navier-Stokes equations on Cartesian grids. A novel coupled level set and moment of fluid method is used to construct the interface. A sequential method is used to position spheres in the cylinder. Preliminary experimental results showed that the tested flow rates resulted in pulse flow. The numerical simulation revealed that air bubbles could merge into larger bubbles and also could break up into smaller bubbles to pass through the pores in the bed. Preliminary results showed that flow passed through regions where the porosity is high. Comparison between the experimental and numerical results in terms of pressure distributions at different flow injection rates will be conducted. Comparison of flow phenomena under terrestrial gravity and microgravity will be made.

The effect of bedload transport on mean and turbulent flow properties

NASA Astrophysics Data System (ADS)

Carbonneau, Patrice E.; Bergeron, Normand E.

2000-11-01

This paper reports the results of a flume experiment that was designed to investigate the effect of bedload transport on mean and turbulent properties of the flow. The experiment consisted of varying the bedload transport rate for a given hydraulic condition, and of measuring the flow velocity profiles using an Acoustic Doppler Velocimeter (ADV) for each transport rate in order to allow for comparison. Bedload transport was produced by injecting gravel-size particles ( D50=7.4 mm) with a conveyer belt mounted at the upstream end of the flume. The results indicate that the effect of bedload on flow characteristics is complex. It is shown that bedload transport causes opposite effects on flow velocity depending on the roughness of the bed and the relative magnitude of flow and sediment transport variables. A better understanding of these conflicting results is obtained from the application of an energy budget approach to the analysis of velocity data. This approach demonstrates that bedload affects flow velocity by modifying the rate of dissipation of turbulent kinetic energy. However, the mechanisms responsible for the modification of turbulent dissipation are still unknown.

Utilizing High-Performance Computing to Investigate Parameter Sensitivity of an Inversion Model for Vadose Zone Flow and Transport

NASA Astrophysics Data System (ADS)

Fang, Z.; Ward, A. L.; Fang, Y.; Yabusaki, S.

2011-12-01

High-resolution geologic models have proven effective in improving the accuracy of subsurface flow and transport predictions. However, many of the parameters in subsurface flow and transport models cannot be determined directly at the scale of interest and must be estimated through inverse modeling. A major challenge, particularly in vadose zone flow and transport, is the inversion of the highly-nonlinear, high-dimensional problem as current methods are not readily scalable for large-scale, multi-process models. In this paper we describe the implementation of a fully automated approach for addressing complex parameter optimization and sensitivity issues on massively parallel multi- and many-core systems. The approach is based on the integration of PNNL's extreme scale Subsurface Transport Over Multiple Phases (eSTOMP) simulator, which uses the Global Array toolkit, with the Beowulf-Cluster inspired parallel nonlinear parameter estimation software, BeoPEST in the MPI mode. In the eSTOMP/BeoPEST implementation, a pre-processor generates all of the PEST input files based on the eSTOMP input file. Simulation results for comparison with observations are extracted automatically at each time step eliminating the need for post-process data extractions. The inversion framework was tested with three different experimental data sets: one-dimensional water flow at Hanford Grass Site; irrigation and infiltration experiment at the Andelfingen Site; and a three-dimensional injection experiment at Hanford's Sisson and Lu Site. Good agreements are achieved in all three applications between observations and simulations in both parameter estimates and water dynamics reproduction. Results show that eSTOMP/BeoPEST approach is highly scalable and can be run efficiently with hundreds or thousands of processors. BeoPEST is fault tolerant and new nodes can be dynamically added and removed. A major advantage of this approach is the ability to use high-resolution geologic models to preserve the spatial structure in the inverse model, which leads to better parameter estimates and improved predictions when using the inverse-conditioned realizations of parameter fields.

A dimensionless parameter approach to the thermal behavior of an aquifer thermal energy storage system

NASA Astrophysics Data System (ADS)

Doughty, C.; Hellstrom, G.; Tsang, C. F.; Claesson, J.

1982-09-01

The purpose of aquifer thermal energy storage (ATES) site-characterization studies is to develop a general procedure whereby the energy recovery factor for a given site may be predicted readily for a wide range of operating conditions without doing detailed numerical simulations. The thermal behavior of a ATES system with steady radial fluid flow around a single injection/production well is discussed. Buoyancy flow is neglected, and the aquifer is confined above and below by impermeable confining layers.

Simple and clean determination of tetracyclines by flow injection analysis

NASA Astrophysics Data System (ADS)

Rodríguez, Michael Pérez; Pezza, Helena Redigolo; Pezza, Leonardo

2016-01-01

An environmentally reliable analytical methodology was developed for direct quantification of tetracycline (TC) and oxytetracycline (OTC) using continuous flow injection analysis with spectrophotometric detection. The method is based on the diazo coupling reaction between the tetracyclines and diazotized sulfanilic acid in a basic medium, resulting in the formation of an intense orange azo compound that presents maximum absorption at 434 nm. Experimental design was used to optimize the analytical conditions. The proposed technique was validated over the concentration range of 1 to 40 μg mL- 1, and was successfully applied to samples of commercial veterinary pharmaceuticals. The detection (LOD) and quantification (LOQ) limits were 0.40 and 1.35 μg mL- 1, respectively. The samples were also analyzed by an HPLC method, and the results showed agreement with the proposed technique. The new flow injection method can be immediately used for quality control purposes in the pharmaceutical industry, facilitating monitoring in real time during the production processes of tetracycline formulations for veterinary use.

Sensitive flow-injection spectrophotometric analysis of bromopride

NASA Astrophysics Data System (ADS)

Lima, Liliane Spazzapam; Weinert, Patrícia Los; Pezza, Leonardo; Pezza, Helena Redigolo

2014-12-01

A flow injection spectrophotometric procedure employing merging zones is proposed for direct bromopride determination in pharmaceutical formulations and biological fluids. The proposed method is based on the reaction between bromopride and p-dimethylaminocinnamaldehyde (p-DAC) in acid medium, in the presence of sodium dodecyl sulfate (SDS), resulting in formation of a violet product (λmax = 565 nm). Experimental design methodologies were used to optimize the experimental conditions. The Beer-Lambert law was obeyed in a bromopride concentration range of 3.63 × 10-7 to 2.90 × 10-5 mol L-1, with a correlation coefficient (r) of 0.9999. The limits of detection and quantification were 1.07 × 10-7 and 3.57 × 10-7 mol L-1, respectively. The proposed method was successfully applied to the determination of bromopride in pharmaceuticals and human urine, and recoveries of the drug from these media were in the ranges 99.6-101.2% and 98.6-102.1%, respectively. This new flow injection procedure does not require any sample pretreatment steps.

Performance of an Axisymmetric Rocket Based Combined Cycle Engine During Rocket Only Operation Using Linear Regression Analysis

NASA Technical Reports Server (NTRS)

Smith, Timothy D.; Steffen, Christopher J., Jr.; Yungster, Shaye; Keller, Dennis J.

1998-01-01

The all rocket mode of operation is shown to be a critical factor in the overall performance of a rocket based combined cycle (RBCC) vehicle. An axisymmetric RBCC engine was used to determine specific impulse efficiency values based upon both full flow and gas generator configurations. Design of experiments methodology was used to construct a test matrix and multiple linear regression analysis was used to build parametric models. The main parameters investigated in this study were: rocket chamber pressure, rocket exit area ratio, injected secondary flow, mixer-ejector inlet area, mixer-ejector area ratio, and mixer-ejector length-to-inlet diameter ratio. A perfect gas computational fluid dynamics analysis, using both the Spalart-Allmaras and k-omega turbulence models, was performed with the NPARC code to obtain values of vacuum specific impulse. Results from the multiple linear regression analysis showed that for both the full flow and gas generator configurations increasing mixer-ejector area ratio and rocket area ratio increase performance, while increasing mixer-ejector inlet area ratio and mixer-ejector length-to-diameter ratio decrease performance. Increasing injected secondary flow increased performance for the gas generator analysis, but was not statistically significant for the full flow analysis. Chamber pressure was found to be not statistically significant.

Fuel-Air Injection Effects on Combustion in Cavity-Based Flameholders in a Supersonic Flow

DTIC Science & Technology

2005-03-01

both fuel and air provided additional capability to tune the cavity such that a more stable decentralized flame results. The addition of air...Mark Gruber of AFRL/PRAS and Mr. Mark Hsu of Innovative Scientific Solutions Inc. for both the support and latitude provided to me in this endeavor...addition of direct air injection to cavity combustion. Direct injection of both fuel and air provided additional capability to tune the cavity such that a

Time-Filtered Navier-Stokes Approach and Emulation of Turbulence-Chemistry Interaction

NASA Technical Reports Server (NTRS)

Liu, Nan-Suey; Wey, Thomas; Shih, Tsan-Hsing

2013-01-01

This paper describes the time-filtered Navier-Stokes approach capable of capturing unsteady flow structures important for turbulent mixing and an accompanying subgrid model directly accounting for the major processes in turbulence-chemistry interaction. They have been applied to the computation of two-phase turbulent combustion occurring in a single-element lean-direct-injection combustor. Some of the preliminary results from this computational effort are presented in this paper.

Fuel cell membrane hydration and fluid metering

DOEpatents

Jones, Daniel O.; Walsh, Michael M.

1999-01-01

A hydration system includes fuel cell fluid flow plate(s) and injection port(s). Each plate has flow channel(s) with respective inlet(s) for receiving respective portion(s) of a given stream of reactant fluid for a fuel cell. Each injection port injects a portion of liquid water directly into its respective flow channel in order to mix its respective portion of liquid water with the corresponding portion of the stream. This serves to hydrate at least corresponding part(s) of a given membrane of the corresponding fuel cell(s). The hydration system may be augmented by a metering system including flow regulator(s). Each flow regulator meters an injecting at inlet(s) of each plate of respective portions of liquid into respective portion(s) of a given stream of fluid by corresponding injection port(s).

Flow injection analysis-flame atomic absorption spectrometry system for indirect determination of sulfite after on-line reduction of solid-phase manganese (IV) dioxide reactor.

PubMed

Zare-Dorabei, Rouholah; Boroun, Shokoufeh; Noroozifar, Meissam

2018-02-01

A new and simple flow injection method followed by atomic absorption spectrometry was developed for indirect determination of sulfite. The proposed method is based on the oxidation of sulfite to sulphate ion using solid-phase manganese dioxide (30% W/W suspended on silica gel beads) reactor. MnO 2 will be reduced to Mn(II) by sample injection in to the column under acidic carrier stream of HNO 3 (pH 2) with flow rate of 3.5mLmin -1 at room temperature. Absorption measurement of Mn(II) which is proportional to the concentration of sulfite in the sample was carried out by atomic absorption spectrometry. The calibration curve was linear up to 25mgL -1 with a detection limit (DL) of 0.08mgL -1 for 400µL injection sample volume. The presented method is efficient toward sulfite determination in sugar and water samples with a relative standard deviation (RSD) less than 1.2% and a sampling rate of about 60h -1 . Copyright © 2017 Elsevier B.V. All rights reserved.

Mathematical modeling heat and mass transfer processes in porous media

NASA Astrophysics Data System (ADS)

Akhmed-Zaki, Darkhan

2013-11-01

On late development stages of oil-fields appears a complex problem of oil-recovery reduction. One of solution approaches is injecting of surfactant together with water in the form of active impurities into the productive layer - for decreasing oil viscosity and capillary forces between ``oil-water'' phases system. In fluids flow the surfactant can be in three states: dissolved in water, dissolved in oil and adsorbed on pore channels' walls. The surfactant's invasion into the reservoir is tracked by its diffusion with reservoir liquid and mass-exchange with two phase (liquid and solid) components of porous structure. Additionally, in this case heat exchange between fluids (injected, residual) and framework of porous medium has practical importance for evaluating of temperature influences on enhancing oil recovery. Now, the problem of designing an adequate mathematical model for describing a simultaneous flowing heat and mass transfer processes in anisotropic heterogeneous porous medium -surfactant injection during at various temperature regimes has not been fully researched. In this work is presents a 2D mathematical model of surfactant injections into the oil reservoir. Description of heat- and mass transfer processes in a porous media is done through differential and kinetic equations. For designing a computational algorithm is used modify version of IMPES method. The sequential and parallel computational algorithms are developed using an adaptive curvilinear meshes which into account heterogeneous porous structures. In this case we can evaluate the boundaries of our process flows - fronts (``invasion'', ``heat'' and ``mass'' transfers), according to the pressure, temperature, and concentration gradient changes.

Large Eddy Simulation of the fuel transport and mixing process in a scramjet combustor with rearwall-expansion cavity

NASA Astrophysics Data System (ADS)

Cai, Zun; Liu, Xiao; Gong, Cheng; Sun, Mingbo; Wang, Zhenguo; Bai, Xue-Song

2016-09-01

Large Eddy Simulation (LES) was employed to investigate the fuel/oxidizer mixing process in an ethylene fueled scramjet combustor with a rearwall-expansion cavity. The numerical solver was first validated for an experimental flow, the DLR strut-based scramjet combustor case. Shock wave structures and wall-pressure distribution from the numerical simulations were compared with experimental data and the numerical results were shown in good agreement with the available experimental data. Effects of the injection location on the flow and mixing process were then studied. It was found that with a long injection distance upstream the cavity, the fuel is transported much further into the main flow and a smaller subsonic zone is formed inside the cavity. Conversely, with a short injection distance, the fuel is entrained more into the cavity and a larger subsonic zone is formed inside the cavity, which is favorable for ignition in the cavity. For the rearwall-expansion cavity, it is suggested that the optimized ignition location with a long upstream injection distance should be in the bottom wall in the middle part of the cavity, while the optimized ignition location with a short upstream injection distance should be in the bottom wall in the front side of the cavity. By employing a cavity direct injection on the rear wall, the fuel mass fraction inside the cavity and the local turbulent intensity will both be increased due to this fueling, and it will also enhance the mixing process which will also lead to increased mixing efficiency. For the rearwall-expansion cavity, the combined injection scheme is expected to be an optimized injection scheme.

Significant Association between Sulfate-Reducing Bacteria and Uranium-Reducing Microbial Communities as Revealed by a Combined Massively Parallel Sequencing-Indicator Species Approach▿ †

PubMed Central

Cardenas, Erick; Wu, Wei-Min; Leigh, Mary Beth; Carley, Jack; Carroll, Sue; Gentry, Terry; Luo, Jian; Watson, David; Gu, Baohua; Ginder-Vogel, Matthew; Kitanidis, Peter K.; Jardine, Philip M.; Zhou, Jizhong; Criddle, Craig S.; Marsh, Terence L.; Tiedje, James M.

2010-01-01

Massively parallel sequencing has provided a more affordable and high-throughput method to study microbial communities, although it has mostly been used in an exploratory fashion. We combined pyrosequencing with a strict indicator species statistical analysis to test if bacteria specifically responded to ethanol injection that successfully promoted dissimilatory uranium(VI) reduction in the subsurface of a uranium contamination plume at the Oak Ridge Field Research Center in Tennessee. Remediation was achieved with a hydraulic flow control consisting of an inner loop, where ethanol was injected, and an outer loop for flow-field protection. This strategy reduced uranium concentrations in groundwater to levels below 0.126 μM and created geochemical gradients in electron donors from the inner-loop injection well toward the outer loop and downgradient flow path. Our analysis with 15 sediment samples from the entire test area found significant indicator species that showed a high degree of adaptation to the three different hydrochemical-created conditions. Castellaniella and Rhodanobacter characterized areas with low pH, heavy metals, and low bioactivity, while sulfate-, Fe(III)-, and U(VI)-reducing bacteria (Desulfovibrio, Anaeromyxobacter, and Desulfosporosinus) were indicators of areas where U(VI) reduction occurred. The abundance of these bacteria, as well as the Fe(III) and U(VI) reducer Geobacter, correlated with the hydraulic connectivity to the substrate injection site, suggesting that the selected populations were a direct response to electron donor addition by the groundwater flow path. A false-discovery-rate approach was implemented to discard false-positive results by chance, given the large amount of data compared. PMID:20729318

Investigation of Mixing a Supersonic Stream with the Flow Downstream of a Wedge

NASA Technical Reports Server (NTRS)

Sheeley, Joseph

1997-01-01

The flow characteristics in the base region of a two-dimensional supersonic compression ramp are investigated. A stream-wise oriented air jet, M = 1.75, is injected through a thin horizontal slot into a supersonic air main flow, M = 2.3, at the end of a two-dimensional compression ramp. The velocity profile and basic characteristics of the flow in the base region immediately following the ramp are determined. Visualization of the flowfield for qualitative observations is accomplished via Dark Central Ground Interferometry (DCGI). Two-dimensional velocity profiles are obtained using Laser Doppler Velocimetry (LDV). The study is the initial phase of a four-year investigation of base flow mixing. The current study is to provide more details of the flowfield.

Synergistic effects of FGF-2 and PDGF-BB on angiogenesis and muscle regeneration in rabbit hindlimb ischemia model.

PubMed

Li, Jie; Wei, Yuquan; Liu, Kang; Yuan, Chuang; Tang, Yajuan; Quan, Qingli; Chen, Ping; Wang, Wei; Hu, Huozhen; Yang, Li

2010-07-01

Combinatorial strategy has been used in therapeutic angiogenesis in animal models of peripheral arterial disease (PAD) and coronary artery disease for decades. Previous studies have shown that basic fibroblast growth factor (FGF-2) and platelet-derived growth factor BB (PDGF-BB) proteins together establish functional and stable vascular networks on mouse corneal and also in animal model of hindlimb ischemia. However, the short half life of protein by single injection is not sufficient to achieve effective dosage, repeated and prolonged injection causes systemic toxicity. Here we study the synergistic effects of FGF-2 and PDGF-BB by intramuscular injection of naked plasmid DNA on therapeutic angiogenesis in rabbit model of hindlimb ischemia. We found that transient delivery of FGF-2 and PDGF-BB naked DNA together resulted in greater increases in capillary growth, collateral formation and popliteal blood flow compared with control and single gene delivery. Our data provided novel evidence of beneficial effects of DNA-based FGF-2 and PDFG-BB on muscle repair after ischemic injury. These findings reveal an alternative therapeutic approach in the treatment of ischemic diseases and even in muscular disorders. Copyright 2010. Published by Elsevier Inc.

A broadband continuous-wave multichannel near-infrared system for measuring regional cerebral blood flow and oxygen consumption in newborn piglets

NASA Astrophysics Data System (ADS)

Diop, Mamadou; Elliott, Jonathan T.; Tichauer, Kenneth M.; Lee, Ting-Yim; St. Lawrence, Keith

2009-05-01

Near-infrared spectroscopy (NIRS) is a promising technique for assessing brain function in newborns, particularly due to its portability and sensitivity to cerebral hemodynamics and oxygenation. Methods for measuring cerebral blood flow (CBF) and cerebral metabolic rate of oxygen (CMRO2) have been developed based on broadband continuous-wave NIRS. However, broadband NIRS apparatus typically have only one detection channel, which limits their applicability to measuring regional CBF and CMRO2. In this study, a relatively simple multiplexing approach based on electronically controlled mechanical shutters is proposed to expand the detection capabilities from one to eight channels. The tradeoff is an increase in the sampling interval; however, this has negligible effects on CBF measurements for intervals less than or equal to 1 s. The ability of the system to detect focal brain injury was demonstrated in piglets by injecting endothelin-1 (ET-1) into the cerebral cortex. For validation, CBF was independently measured by computed tomography (CT) perfusion. The average reduction in CBF from the source-detector pair that interrogated the injured region was 51%±9%, which was in good agreement with the CBF reduction measured by CT perfusion (55%±5%). No significant changes in regional CMRO2 were observed. The average regional differential pathlength prior to ET-1 injection was 8.4±0.2 cm (range of 7.1-9.6 cm) and did not significantly change after the injury.

A broadband continuous-wave multichannel near-infrared system for measuring regional cerebral blood flow and oxygen consumption in newborn piglets.

PubMed

Diop, Mamadou; Elliott, Jonathan T; Tichauer, Kenneth M; Lee, Ting-Yim; St Lawrence, Keith

2009-05-01

Near-infrared spectroscopy (NIRS) is a promising technique for assessing brain function in newborns, particularly due to its portability and sensitivity to cerebral hemodynamics and oxygenation. Methods for measuring cerebral blood flow (CBF) and cerebral metabolic rate of oxygen (CMRO(2)) have been developed based on broadband continuous-wave NIRS. However, broadband NIRS apparatus typically have only one detection channel, which limits their applicability to measuring regional CBF and CMRO(2). In this study, a relatively simple multiplexing approach based on electronically controlled mechanical shutters is proposed to expand the detection capabilities from one to eight channels. The tradeoff is an increase in the sampling interval; however, this has negligible effects on CBF measurements for intervals less than or equal to 1 s. The ability of the system to detect focal brain injury was demonstrated in piglets by injecting endothelin-1 (ET-1) into the cerebral cortex. For validation, CBF was independently measured by computed tomography (CT) perfusion. The average reduction in CBF from the source-detector pair that interrogated the injured region was 51%+/-9%, which was in good agreement with the CBF reduction measured by CT perfusion (55%+/-5%). No significant changes in regional CMRO(2) were observed. The average regional differential pathlength prior to ET-1 injection was 8.4+/-0.2 cm (range of 7.1-9.6 cm) and did not significantly change after the injury.

String flash-boiling in gasoline direct injection simulations with transient needle motion

DOE PAGES

Baldwin, Eli T.; Grover, Jr., Ronald O.; Parrish, Scott E.; ...

2016-09-06

A computational study was performed to investigate the influence of transient needle motion on gasoline direct injection (GDI) internal nozzle flow and near-field sprays. Simulations were conducted with a compressible Eulerian flow solver modeling liquid, vapor, and non-condensable gas phases with a diffuse interface. Variable rate generation and condensation of fuel vapor were captured using the homogeneous relaxation model (HRM). The non-flashing (spray G) and flashing (spray G2) conditions specified by the Engine Combustion Network were modeled using the nominal spray G nozzle geometry and transient needle lift and wobble were based upon ensemble averaged x-ray imaging preformed at Argonnemore » National Lab. The minimum needle lift simulated was 5 μm and dynamic mesh motion was achieved with Laplacian smoothing. The results were qualitatively validated against experimental imaging and the experimental rate of injection profile was captured accurately using pressure boundary conditions and needle motion to actu- ate the injection. Needle wobble was found to have no measurable effect on the flow. Low needle lift is shown to result in vapor generation as fuel rushes past the needle. In conclusion, the internal injector flow is shown to contain many transient and interacting vortices which cause perturbations in the spray angle, fluctuations in the mass flux, and frequently result in string flash-boiling.« less

3-D numerical evaluation of density effects on tracer tests.

PubMed

Beinhorn, M; Dietrich, P; Kolditz, O

2005-12-01

In this paper we present numerical simulations carried out to assess the importance of density-dependent flow on tracer plume development. The scenario considered in the study is characterized by a short-term tracer injection phase into a fully penetrating well and a natural hydraulic gradient. The scenario is thought to be typical for tracer tests conducted in the field. Using a reference case as a starting point, different model parameters were changed in order to determine their importance to density effects. The study is based on a three-dimensional model domain. Results were interpreted using concentration contours and a first moment analysis. Tracer injections of 0.036 kg per meter of saturated aquifer thickness do not cause significant density effects assuming hydraulic gradients of at least 0.1%. Higher tracer input masses, as used for geoelectrical investigations, may lead to buoyancy-induced flow in the early phase of a tracer test which in turn impacts further plume development. This also holds true for shallow aquifers. Results of simulations with different tracer injection rates and durations imply that the tracer input scenario has a negligible effect on density flow. Employing model cases with different realizations of a log conductivity random field, it could be shown that small variations of hydraulic conductivity in the vicinity of the tracer injection well have a major control on the local tracer distribution but do not mask effects of buoyancy-induced flow.

String flash-boiling in gasoline direct injection simulations with transient needle motion

DOE Office of Scientific and Technical Information (OSTI.GOV)

Baldwin, Eli T.; Grover, Jr., Ronald O.; Parrish, Scott E.

A computational study was performed to investigate the influence of transient needle motion on gasoline direct injection (GDI) internal nozzle flow and near-field sprays. Simulations were conducted with a compressible Eulerian flow solver modeling liquid, vapor, and non-condensable gas phases with a diffuse interface. Variable rate generation and condensation of fuel vapor were captured using the homogeneous relaxation model (HRM). The non-flashing (spray G) and flashing (spray G2) conditions specified by the Engine Combustion Network were modeled using the nominal spray G nozzle geometry and transient needle lift and wobble were based upon ensemble averaged x-ray imaging preformed at Argonnemore » National Lab. The minimum needle lift simulated was 5 μm and dynamic mesh motion was achieved with Laplacian smoothing. The results were qualitatively validated against experimental imaging and the experimental rate of injection profile was captured accurately using pressure boundary conditions and needle motion to actu- ate the injection. Needle wobble was found to have no measurable effect on the flow. Low needle lift is shown to result in vapor generation as fuel rushes past the needle. In conclusion, the internal injector flow is shown to contain many transient and interacting vortices which cause perturbations in the spray angle, fluctuations in the mass flux, and frequently result in string flash-boiling.« less

Influence of injection mode on transport properties in kilometer-scale three-dimensional discrete fracture networks

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hyman, Jeffrey De'Haven; Painter, S. L.; Viswanathan, H.

We investigate how the choice of injection mode impacts transport properties in kilometer-scale three-dimensional discrete fracture networks (DFN). The choice of injection mode, resident and flux-weighted, is designed to mimic different physical phenomena. It has been hypothesized that solute plumes injected under resident conditions evolve to behave similarly to solutes injected under flux-weighted conditions. Previously, computational limitations have prohibited the large-scale simulations required to investigate this hypothesis. We investigate this hypothesis by using a high-performance DFN suite, dfnWorks, to simulate flow in kilometer-scale three-dimensional DFNs based on fractured granite at the Forsmark site in Sweden, and adopt a Lagrangian approachmore » to simulate transport therein. Results show that after traveling through a pre-equilibrium region, both injection methods exhibit linear scaling of the first moment of travel time and power law scaling of the breakthrough curve with similar exponents, slightly larger than 2. Lastly, the physical mechanisms behind this evolution appear to be the combination of in-network channeling of mass into larger fractures, which offer reduced resistance to flow, and in-fracture channeling, which results from the topology of the DFN.« less

Influence of injection mode on transport properties in kilometer-scale three-dimensional discrete fracture networks

DOE PAGES

Hyman, Jeffrey De'Haven; Painter, S. L.; Viswanathan, H.; ...

2015-09-12

We investigate how the choice of injection mode impacts transport properties in kilometer-scale three-dimensional discrete fracture networks (DFN). The choice of injection mode, resident and flux-weighted, is designed to mimic different physical phenomena. It has been hypothesized that solute plumes injected under resident conditions evolve to behave similarly to solutes injected under flux-weighted conditions. Previously, computational limitations have prohibited the large-scale simulations required to investigate this hypothesis. We investigate this hypothesis by using a high-performance DFN suite, dfnWorks, to simulate flow in kilometer-scale three-dimensional DFNs based on fractured granite at the Forsmark site in Sweden, and adopt a Lagrangian approachmore » to simulate transport therein. Results show that after traveling through a pre-equilibrium region, both injection methods exhibit linear scaling of the first moment of travel time and power law scaling of the breakthrough curve with similar exponents, slightly larger than 2. Lastly, the physical mechanisms behind this evolution appear to be the combination of in-network channeling of mass into larger fractures, which offer reduced resistance to flow, and in-fracture channeling, which results from the topology of the DFN.« less

Prediction of Gas Injection Performance for Heterogeneous Reservoirs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Blunt, Martin J.; Orr, Franklin M.

This report describes research carried out in the Department of Petroleum Engineering at Stanford University from September 1997 - September 1998 under the second year of a three-year grant from the Department of Energy on the "Prediction of Gas Injection Performance for Heterogeneous Reservoirs." The research effort is an integrated study of the factors affecting gas injection, from the pore scale to the field scale, and involves theoretical analysis, laboratory experiments, and numerical simulation. The original proposal described research in four areas: (1) Pore scale modeling of three phase flow in porous media; (2) Laboratory experiments and analysis of factorsmore » influencing gas injection performance at the core scale with an emphasis on the fundamentals of three phase flow; (3) Benchmark simulations of gas injection at the field scale; and (4) Development of streamline-based reservoir simulator. Each state of the research is planned to provide input and insight into the next stage, such that at the end we should have an integrated understanding of the key factors affecting field scale displacements.« less

Development of Science-Based Permitting Guidance for Geological Sequestration of CO2 in Deep Saline Aquifers Based on Modeling and Risk Assessment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jean-Philippe Nicot; Renaud Bouroullec; Hugo Castellanos

2006-06-30

Underground carbon storage may become one of the solutions to address global warming. However, to have an impact, carbon storage must be done at a much larger scale than current CO{sub 2} injection operations for enhanced oil recovery. It must also include injection into saline aquifers. An important characteristic of CO{sub 2} is its strong buoyancy--storage must be guaranteed to be sufficiently permanent to satisfy the very reason that CO{sub 2} is injected. This long-term aspect (hundreds to thousands of years) is not currently captured in legislation, even if the U.S. has a relatively well-developed regulatory framework to handle carbonmore » storage, especially in the operational short term. This report proposes a hierarchical approach to permitting in which the State/Federal Government is responsible for developing regional assessments, ranking potential sites (''General Permit'') and lessening the applicant's burden if the general area of the chosen site has been ranked more favorably. The general permit would involve determining in the regional sense structural (closed structures), stratigraphic (heterogeneity), and petrophysical (flow parameters such as residual saturation) controls on the long-term fate of geologically sequestered CO{sub 2}. The state-sponsored regional studies and the subsequent local study performed by the applicant will address the long-term risk of the particular site. It is felt that a performance-based approach rather than a prescriptive approach is the most appropriate framework in which to address public concerns. However, operational issues for each well (equivalent to the current underground injection control-UIC-program) could follow regulations currently in place. Area ranking will include an understanding of trapping modes. Capillary (due to residual saturation) and structural (due to local geological configuration) trappings are two of the four mechanisms (the other two are solubility and mineral trappings), which are the most relevant to the time scale of interest. The most likely pathways for leakage, if any, are wells and faults. We favor a defense-in-depth approach, in which storage permanence does not rely upon a primary seal only but assumes that any leak can be contained by geologic processes before impacting mineral resources, fresh ground water, or ground surface. We examined the Texas Gulf Coast as an example of an attractive target for carbon storage. Stacked sand-shale layers provide large potential storage volumes and defense-in-depth leakage protection. In the Texas Gulf Coast, the best way to achieve this goal is to establish the primary injection level below the total depth of most wells (>2,400 m-8,000 ft). In addition, most faults, particularly growth faults, present at the primary injection level do not reach the surface. A potential methodology, which includes an integrated approach comprising the whole chain of potential events from leakage from the primary site to atmospheric impacts, is also presented. It could be followed by the State/Federal Government, as well as by the operators.« less

Detection of phenolic compounds in flow systems based on tyrosinase-modified reticulated vitreous carbon electrodes.

PubMed

Peña, N; Reviejo, A J; Pingarrón, J M

2001-08-03

The fabrication and performance of a reticulated vitreous carbon (RVC)-based tyrosinase flow-through electrode, in which the enzyme was covalently immobilized, is reported. The bioelectrode was tested as an amperometric detector for phenolic compounds. Variables affecting the construction of the enzyme flow-through electrode such as the RVC chemical pretreatment procedure, the enzyme immobilization method in the RVC matrix, the enzyme loading and the pH value of the buffer solution used, were optimized by flow-injection with amperometric detection. A good immobilization of the enzyme in the RVC matrix, in spite of the hydrodynamic conditions, was found. The same tyrosinase-RVC electrode could be used with no significant loss of the amperometric response for around 20 days, and reproducible responses could be achieved with different electrodes constructed in the same manner. Moreover, the operational stability of the bioelectrode was tested under continuous monitorization conditions. Calibration plots by flow injection with amperometric detection at -0.20 V were obtained for phenol, 2,4-dimethylphenol; 3-chlorophenol; 4-chlorophenol; 4-chloro-3-methylphenol and 2-aminophenol, with detection limits ranging from 2 mug l(-1) (4-chloro-3-methylphenol) to 2 mg l(-1).

A multisyringe flow-based system for kinetic-catalytic determination of cobalt(II).

PubMed

Chaparro, Laura; Ferrer, Laura; Leal, Luz; Cerdà, Víctor

2015-02-01

A kinetic-catalytic method for cobalt determination based on the catalytic effect of cobalt(II) on the oxidative coupling of 1,2-dihydroxyanthraquinone (alizarin) was automated exploiting multisyringe flow injection analysis (MSFIA). The proposed method was performed at pH 9.2, resulting in a discoloration process in the presence of hydrogen peroxide. The fixed-time approach was employed for analytical signal measurement. The spectrophotometric detection was used exploiting a liquid waveguide capillary cell (LWCC), of 1m optical length at 465 nm. The optimization was carried out by a multivariate approach, reaching critical values of 124 µmol L(-1) and 0.22 mol L(-1) for alizarin and hydrogen peroxide, respectively, and 67°C of reagent temperature. A sample volume of 150 µL was used allowing a sampling rate of 30h(-1). Under optimal conditions, calibration curve was linear in the range of 1-200 µg L(-1) Co, achieving a DL of 0.3 µg L(-1) Co. The repeatability, expressed as relative standard deviation (RSD) was lower than 1%. The proposed analytical procedure was applied to the determination of cobalt in cobalt gluconate and different forms of vitamin B12, cyanocobalamin and hydroxicobalamin with successful results showing recoveries around 95%. Copyright © 2014 Elsevier B.V. All rights reserved.

Heavy oil recovery process: Conceptual engineering of a downhole methanator and preliminary estimate of facilities cost for application to North Slope Alaska

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gondouin, M.

1991-10-31

The West Sak (Upper Cretaceous) sands, overlaying the Kuparuk field, would rank among the largest known oil fields in the US, but technical difficulties have so far prevented its commercial exploitation. Steam injection is the most successful and the most commonly-used method of heavy oil recovery, but its application to the West Sak presents major problems. Such difficulties may be overcome by using a novel approach, in which steam is generated downhole in a catalytic Methanator, from Syngas made at the surface from endothermic reactions (Table 1). The Methanator effluent, containing steam and soluble gases resulting from exothermic reactions (Tablemore » 1), is cyclically injected into the reservoir by means of a horizontal drainhole while hot produced fluids flow form a second drainhole into a central production tubing. The downhole reactor feed and BFW flow downward to two concentric tubings. The large-diameter casing required to house the downhole reactor assembly is filled above it with Arctic Pack mud, or crude oil, to further reduce heat leaks. A quantitative analysis of this production scheme for the West Sak required a preliminary engineering of the downhole and surface facilities and a tentative forecast of well production rates. The results, based on published information on the West Sak, have been used to estimate the cost of these facilities, per daily barrel of oil produced. A preliminary economic analysis and conclusions are presented together with an outline of future work. Economic and regulatory conditions which would make this approach viable are discussed. 28 figs.« less

Surface self-potential patterns related to transmissive fracture trends during a water injection test

NASA Astrophysics Data System (ADS)

DesRoches, A. J.; Butler, K. E.; MacQuarrie, K. TB

2018-03-01

Variations in self-potential (SP) signals were recorded over an electrode array during a constant head injection test in a fractured bedrock aquifer. Water was injected into a 2.2 m interval isolated between two inflatable packers at 44 m depth in a vertical well. Negative SP responses were recorded on surface corresponding to the start of the injection period with strongest magnitudes recorded in electrodes nearest the well. SP response decreased in magnitude at electrodes further from the well. Deflation of the packer system resulted in a strong reversal in the SP signal. Anomalous SP patterns observed at surface at steady state were found to be aligned with dominant fracture strike orientations found within the test interval. Numerical modelling of fluid and current flow within a simplified fracture network showed that azimuthal patterns in SP are mainly controlled by transmissive fracture orientations. The strongest SP gradients occur parallel to hydraulic gradients associated with water flowing out of the transmissive fractures into the tighter matrix and other less permeable cross-cutting fractures. Sensitivity studies indicate that increasing fracture frequency near the well increases the SP magnitude and enhances the SP anomaly parallel to the transmissive set. Decreasing the length of the transmissive fractures leads to more fluid flow into the matrix and into cross-cutting fractures proximal to the well, resulting in a more circular and higher magnitude SP anomaly. Results from the field experiment and modelling provide evidence that surface-based SP monitoring during constant head injection tests has the ability to identify groundwater flow pathways within a fractured bedrock aquifer.

Fracture Flow Characterization from Seismic and Electric Properties: Insight from Experimental and Numerical Approaches

NASA Astrophysics Data System (ADS)

Sawayama, K.; Kitamura, K.; Tsuji, T.; Fujimitsu, Y.

2017-12-01

The estimation of fluid flow and its distribution in the fracture is essential to evaluate subsurface fluid (e.g., geothermal water, ground water, oil and gas). Recently, fluid flow in the geothermal reservoir has been attracting attention to develop EGS (enhanced geothermal system) technique. To detect the fluid distribution under the ground, geophysical exploration such as seismic and electromagnetic methods have been broadly applied. For better interpretation of these exploration data, more detailed investigation about the effect of fluid on seismic and electric properties of fracture is required. In this study, we measured and calculated seismic and electric properties of a cracked rock to discuss the effect of water distribution and saturation on them as well as fluid flow. For the experimental observation, we developed the technique to measure electrical impedance, P-wave velocity and water saturation simultaneously during the fluid-flow test. The test has been conducted as follows; a cracked andesite core sample was filled with nitrogen gas (Pp = 10 MPa) under 20 MPa of confining pressure and then, brine (1wt.%-KCl, 1.75 S/m) was injected into the sample to replace the gas. During the test, water saturation, permeability, electrical impedance and P-wave velocity were measured. As a result of this experimental study, electrical impedance dramatically decreased from 105 to 103 Ω and P-wave velocity increased by 2% due to the brine injection. This remarkable change of the electrical impedance could be due to the replacement of pre-filled nitrogen gas to the brine in the broad fracture. After the brine injection, electrical impedance decreased with injection pressure by up to 40% while P-wave velocity was almost constant. This decrease of electrical impedance could be related to the flow to the narrow path (microcrack) which cannot be detected by P-wave velocity. These two types of fluid flow mechanism were also suggested from other parameters such as permeability, water saturation and saturation exponent of Archie's law. To quantify the fluid flow and its distribution in the fracture, we applied fluid flow simulation by LBM (Lattice Boltzmann Method). From this result, we calculate physical parameters by FEM and FDM and then discuss effect of fluid on them as well as their comparison with experimental results.

Heat transfer to two-phase air/water mixtures flowing in small tubes with inlet disequilibrium

NASA Technical Reports Server (NTRS)

Janssen, J. M.; Florschuetz, L. W.; Fiszdon, J. P.

1986-01-01

The cooling of gas turbine components was the subject of considerable research. The problem is difficult because the available coolant, compressor bleed air, is itself quite hot and has relatively poor thermophysical properties for a coolant. Injecting liquid water to evaporatively cool the air prior to its contact with the hot components was proposed and studied, particularly as a method of cooling for contingency power applications. Injection of a small quantity of cold liquid water into a relatively hot coolant air stream such that evaporation of the liquid is still in process when the coolant contacts the hot component was studied. No approach was found whereby heat transfer characteristics could be confidently predicted for such a case based solely on prior studies. It was not clear whether disequilibrium between phases at the inlet to the hot component section would improve cooling relative to that obtained where equilibrium was established prior to contact with the hot surface.

Analysis of pedestrian dynamics in counter flow via an extended lattice gas model.

PubMed

Kuang, Hua; Li, Xingli; Song, Tao; Dai, Shiqiang

2008-12-01

The modeling of human behavior is an important approach to reproduce realistic phenomena for pedestrian flow. In this paper, an extended lattice gas model is proposed to simulate pedestrian counter flow under the open boundary conditions by considering the human subconscious behavior and different maximum velocities. The simulation results show that the presented model can capture some essential features of pedestrian counter flows, such as lane formation, segregation effect, and phase separation at higher densities. In particular, an interesting feature that the faster walkers overtake the slower ones and then form a narrow-sparse walkway near the central partition line is discovered. The phase diagram comparison and analysis show that the subconscious behavior plays a key role in reducing the occurrence of jam cluster. The effects of the symmetrical and asymmetrical injection rate, different partition lines, and different combinations of maximum velocities on pedestrian flow are investigated. An important conclusion is that it is needless to separate faster and slower pedestrians in the same direction by a partition line. Furthermore, the increase of the number of faster walkers does not always benefit the counter flow in all situations. It depends on the magnitude and asymmetry of injection rate. And at larger maximum velocity, the obtained critical transition point corresponding to the maximum flow rate of the fundamental diagram is in good agreement with the empirical results.

A multi-objective simulation-optimization model for in situ bioremediation of groundwater contamination: Application of bargaining theory

NASA Astrophysics Data System (ADS)

Raei, Ehsan; Nikoo, Mohammad Reza; Pourshahabi, Shokoufeh

2017-08-01

In the present study, a BIOPLUME III simulation model is coupled with a non-dominating sorting genetic algorithm (NSGA-II)-based model for optimal design of in situ groundwater bioremediation system, considering preferences of stakeholders. Ministry of Energy (MOE), Department of Environment (DOE), and National Disaster Management Organization (NDMO) are three stakeholders in the groundwater bioremediation problem in Iran. Based on the preferences of these stakeholders, the multi-objective optimization model tries to minimize: (1) cost; (2) sum of contaminant concentrations that violate standard; (3) contaminant plume fragmentation. The NSGA-II multi-objective optimization method gives Pareto-optimal solutions. A compromised solution is determined using fallback bargaining with impasse to achieve a consensus among the stakeholders. In this study, two different approaches are investigated and compared based on two different domains for locations of injection and extraction wells. At the first approach, a limited number of predefined locations is considered according to previous similar studies. At the second approach, all possible points in study area are investigated to find optimal locations, arrangement, and flow rate of injection and extraction wells. Involvement of the stakeholders, investigating all possible points instead of a limited number of locations for wells, and minimizing the contaminant plume fragmentation during bioremediation are new innovations in this research. Besides, the simulation period is divided into smaller time intervals for more efficient optimization. Image processing toolbox in MATLAB® software is utilized for calculation of the third objective function. In comparison with previous studies, cost is reduced using the proposed methodology. Dispersion of the contaminant plume is reduced in both presented approaches using the third objective function. Considering all possible points in the study area for determining the optimal locations of the wells in the second approach leads to more desirable results, i.e. decreasing the contaminant concentrations to a standard level and 20% to 40% cost reduction.

Unsteady boundary-layer injection

NASA Technical Reports Server (NTRS)

Telionis, D. P.; Jones, G. S.

1981-01-01

The boundary-layer equations for two-dimensional incompressible flow are integrated numerically for the flow over a flat plate and a Howarth body. Injection is introduced either impulsively or periodically along a narrow strip. Results indicate that injection perpendicular to the wall is transmitted instantly across the boundary layer and has little effect on the velocity profile parallel to the wall. The effect is a little more noticeable for flows with adverse pressure gradients. Injection parallel to the wall results in fuller velocity profiles. Parallel and oscillatory injection appears to influence the mean. The amplitude of oscillation decreases with distance from the injection strip but further downstream it increases again in a manner reminiscent of an unstable process.

Swozzle based burner tube premixer including inlet air conditioner for low emissions combustion

DOEpatents

Tuthill, Richard Sterling; Bechtel, II, William Theodore; Benoit, Jeffrey Arthur; Black, Stephen Hugh; Bland, Robert James; DeLeonardo, Guy Wayne; Meyer, Stefan Martin; Taura, Joseph Charles; Battaglioli, John Luigi

2002-01-01

A burner for use in a combustion system of a heavy-duty industrial gas turbine includes a fuel/air premixer having an air inlet, a fuel inlet, and an annular mixing passage. The fuel/air premixer mixes fuel and air into a uniform mixture for injection into a combustor reaction zone. The burner also includes an inlet flow conditioner disposed at the air inlet of the fuel/air premixer for controlling a radial and circumferential distribution of incoming air. The pattern of perforations in the inlet flow conditioner is designed such that a uniform air flow distribution is produced at the swirler inlet annulus in both the radial and circumference directions. The premixer includes a swozzle assembly having a series of preferably air foil shaped turning vanes that impart swirl to the airflow entering via the inlet flow conditioner. Each air foil contains internal fuel flow passages that introduce natural gas fuel into the air stream via fuel metering holes that pass through the walls of the air foil shaped turning vanes. By injecting fuel in this manner, an aerodynamically clean flow field is maintained throughout the premixer. By injecting fuel via two separate passages, the fuel/air mixture strength distribution can be controlled in the radial direction to obtain optimum radial concentration profiles for control of emissions, lean blow outs, and combustion driven dynamic pressure activity as machine and combustor load are varied.

Analysis of In-Situ Stress During EGS Resource Development at The Geysers, CA

NASA Astrophysics Data System (ADS)

Boyd, O. S.; Dreger, D. S.; Gritto, R.

2016-12-01

Creating, identifying, and managing fractures and flow paths are essential tasks during Enhanced Geothermal Systems (EGS) resource development. Successful generation of a fracture network requires a priori knowledge of in-situ stress and natural fracture orientation and spacing. However, because the orientation and magnitude of in-situ stress may not be reliably available, and injecting fluids at high rates and volume may disturb the natural stress state, it is advantageous to monitor in-situ stress during the injection process. In this study we investigate M ≥ 1.3 seismicity in the vicinity of EGS development in the Northwest Geysers Prati 32 (P-32) injection well and Prati State 31 (PS-31) production well to determine moment magnitudes and focal mechanisms of events that occur before and during reservoir stimulation starting October 6, 2011. In general, event rate and magnitude increase as well as variability in focal mechanism during injection operations. We use our focal mechanism catalog of more than 150 events to estimate the stress tensor using the approach outlined in Hardebeck and Michaels (2006). Preliminary results of the stress inversion suggest temporal changes in the orientation of the principal stress axes during the first year of injection. It is found that the tension axis remains stable while the trend and plunge of the intermediate axis varies the most. The variations appear to be well resolved based on the 95% confidence intervals from the bootstrap analysis.

Partial Cavity Flows at High Reynolds Numbers

NASA Astrophysics Data System (ADS)

Makiharju, Simo; Elbing, Brian; Wiggins, Andrew; Dowling, David; Perlin, Marc; Ceccio, Steven

2009-11-01

Partial cavity flows created for friction drag reduction were examined on a large-scale. Partial cavities were investigated at Reynolds numbers up to 120 million, and stable cavities with frictional drag reduction of more than 95% were attained at optimal conditions. The model used was a 3 m wide and 12 m long flat plate with a plenum on the bottom. To create the partial cavity, air was injected at the base of an 18 cm backwards-facing step 2.1 m from the leading edge. The geometry at the cavity closure was varied for different flow speeds to optimize the closure of the cavity. Cavity gas flux, thickness, frictional loads, and cavity pressures were measured over a range of flow speeds and air injection fluxes. High-speed video was used extensively to investigate the unsteady three dimensional cavity closure, the overall cavity shape and oscillations.

Low gravity transfer line chilldown

NASA Technical Reports Server (NTRS)

Antar, Basil N.; Collins, Frank G.; Kawaji, Masahiro

1992-01-01

The progress to date is presented in providing predictive capabilities for the transfer line chilldown problem in low gravity environment. A low gravity experimental set up was designed and flown onboard the NASA/KC-135 airplane. Some results of this experimental effort are presented. The cooling liquid for these experiments was liquid nitrogen. The boiling phenomenon was investigated in this case using flow visualization techniques as well as recording wall temperatures. The flow field was established by injecting cold liquid in a heated tube whose temperature was set above saturation values. The tubes were vertically supported with the liquid injected from the lower end of the tube. The results indicate substantial differences in the flow patterns established during boiling between the ground based, (1-g), experiments and the flight experiments, (low-g). These differences in the flow patterns will be discussed and some explanations will be offered.

Reduction of Altitude Diffuser Jet Noise Using Water Injection

NASA Technical Reports Server (NTRS)

Allgood, Daniel C.; Saunders, Grady P.; Langford, Lester A.

2014-01-01

A feasibility study on the effects of injecting water into the exhaust plume of an altitude rocket diffuser for the purpose of reducing the far-field acoustic noise has been performed. Water injection design parameters such as axial placement, angle of injection, diameter of injectors, and mass flow rate of water have been systematically varied during the operation of a subscale altitude test facility. The changes in acoustic far-field noise were measured with an array of free-field microphones in order to quantify the effects of the water injection on overall sound pressure level spectra and directivity. The results showed significant reductions in noise levels were possible with optimum conditions corresponding to water injection at or just upstream of the exit plane of the diffuser. Increasing the angle and mass flow rate of water injection also showed improvements in noise reduction. However, a limit on the maximum water flow rate existed as too large of flow rate could result in un-starting the supersonic diffuser.

Reduction of Altitude Diffuser Jet Noise Using Water Injection

NASA Technical Reports Server (NTRS)

Allgood, Daniel C.; Saunders, Grady P.; Langford, Lester A.

2011-01-01

A feasibility study on the effects of injecting water into the exhaust plume of an altitude rocket diffuser for the purpose of reducing the far-field acoustic noise has been performed. Water injection design parameters such as axial placement, angle of injection, diameter of injectors, and mass flow rate of water have been systematically varied during the operation of a subscale altitude test facility. The changes in acoustic far-field noise were measured with an array of free-field microphones in order to quantify the effects of the water injection on overall sound pressure level spectra and directivity. The results showed significant reductions in noise levels were possible with optimum conditions corresponding to water injection at or just upstream of the exit plane of the diffuser. Increasing the angle and mass flow rate of water injection also showed improvements in noise reduction. However, a limit on the maximum water flow rate existed as too large of flow rate could result in un-starting the supersonic diffuser.

Study of effects of injector geometry on fuel-air mixing and combustion

NASA Technical Reports Server (NTRS)

Bangert, L. H.; Roach, R. L.

1977-01-01

An implicit finite-difference method has been developed for computing the flow in the near field of a fuel injector as part of a broader study of the effects of fuel injector geometry on fuel-air mixing and combustion. Detailed numerical results have been obtained for cases of laminar and turbulent flow without base injection, corresponding to the supersonic base flow problem. These numerical results indicated that the method is stable and convergent, and that significant savings in computer time can be achieved, compared with explicit methods.

A qualitative view of cryogenic fluid injection into high speed flows

NASA Technical Reports Server (NTRS)

Hendricks, R. C.; Schlumberger, J.; Proctor, M.

1991-01-01

The injection of supercritical pressure, subcritical temperature fluids, into a 2-D, ambient, static temperature and static pressure supersonic tunnel and free jet supersonic nitrogen flow field was observed. Observed patterns with fluid air were the same as those observed for fluid nitrogen injected into the tunnel at 90 deg to the supersonic flow. The nominal injection pressure was of 6.9 MPa and tunnel Mach number was 2.7. When injected directly into and opposing the tunnel exhaust flow, the observed patterns with fluid air were similar to those observed for fluid nitrogen but appeared more diffusive. Cryogenic injection creates a high density region within the bow shock wake but the standoff distance remains unchanged from the gaseous value. However, as the temperature reaches a critical value, the shock faded and advanced into the supersonic stream. For both fluids, nitrogen and air, the phenomena was completely reversible.

PAB3D Simulations of a Nozzle with Fluidic Injection for Yaw Thrust-Vector Control

NASA Technical Reports Server (NTRS)

Deere, Karen A.

1998-01-01

An experimental and computational study was conducted on an exhaust nozzle with fluidic injection for yaw thrust-vector control. The nozzle concept was tested experimentally in the NASA Langley Jet Exit Test Facility (JETF) at nozzle pressure ratios up to 4 and secondary fluidic injection flow rates up to 15 percent of the primary flow rate. Although many injection-port geometries and two nozzle planforms (symmetric and asymmetric) were tested experimentally, this paper focuses on the computational results of the more successful asymmetric planform with a slot injection port. This nozzle concept was simulated with the Navier-Stokes flow solver, PAB3D, invoking the Shih, Zhu, and Lumley algebraic Reynolds stress turbulence model (ASM) at nozzle pressure ratios (NPRs) of 2,3, and 4 with secondary to primary injection flow rates (w(sub s)/w(sub p)) of 0, 2, 7 and 10 percent.

Inverse modeling of ground surface uplift and pressure with iTOUGH-PEST and TOUGH-FLAC: The case of CO2 injection at In Salah, Algeria

NASA Astrophysics Data System (ADS)

Rinaldi, Antonio P.; Rutqvist, Jonny; Finsterle, Stefan; Liu, Hui-Hai

2017-11-01

Ground deformation, commonly observed in storage projects, carries useful information about processes occurring in the injection formation. The Krechba gas field at In Salah (Algeria) is one of the best-known sites for studying ground surface deformation during geological carbon storage. At this first industrial-scale on-shore CO2 demonstration project, satellite-based ground-deformation monitoring data of high quality are available and used to study the large-scale hydrological and geomechanical response of the system to injection. In this work, we carry out coupled fluid flow and geomechanical simulations to understand the uplift at three different CO2 injection wells (KB-501, KB-502, KB-503). Previous numerical studies focused on the KB-502 injection well, where a double-lobe uplift pattern has been observed in the ground-deformation data. The observed uplift patterns at KB-501 and KB-503 have single-lobe patterns, but they can also indicate a deep fracture zone mechanical response to the injection. The current study improves the previous modeling approach by introducing an injection reservoir and a fracture zone, both responding to a Mohr-Coulomb failure criterion. In addition, we model a stress-dependent permeability and bulk modulus, according to a dual continuum model. Mechanical and hydraulic properties are determined through inverse modeling by matching the simulated spatial and temporal evolution of uplift to InSAR observations as well as by matching simulated and measured pressures. The numerical simulations are in agreement with both spatial and temporal observations. The estimated values for the parameterized mechanical and hydraulic properties are in good agreement with previous numerical results. In addition, the formal joint inversion of hydrogeological and geomechanical data provides measures of the estimation uncertainty.

Inverse modeling of ground surface uplift and pressure with iTOUGH-PEST and TOUGH-FLAC: The case of CO2 injection at In Salah, Algeria

DOE PAGES

Rinaldi, Antonio P.; Rutqvist, Jonny; Finsterle, Stefan; ...

2016-10-24

Ground deformation, commonly seen in storage projects, carries useful information about processes occurring in the injection formation. The Krechba gas field at In Salah (Algeria) is one of the best-known sites for studying ground surface deformation during geological carbon storage. At this first industrial-scale on-shore CO 2 demonstration project, satellite-based ground-deformation monitoring data of high quality are available and used to study the large-scale hydrological and geomechanical response of the system to injection. In this work, we carry out coupled fluid flow and geomechanical simulations to understand the uplift at three different CO 2 injection wells (KB-501, KB-502, KB-503). Previousmore » numerical studies focused on the KB-502 injection well, where a double-lobe uplift pattern has been observed in the ground-deformation data. The observed uplift patterns at KB-501 and KB-503 have single-lobe patterns, but they can also indicate a deep fracture zone mechanical response to the injection.The current study improves the previous modeling approach by introducing an injection reservoir and a fracture zone, both responding to a Mohr-Coulomb failure criterion. In addition, we model a stress-dependent permeability and bulk modulus, according to a dual continuum model. Mechanical and hydraulic properties are determined through inverse modeling by matching the simulated spatial and temporal evolution of uplift to InSAR observations as well as by matching simulated and measured pressures. The numerical simulations are in agreement with both spatial and temporal observations. The estimated values for the parameterized mechanical and hydraulic properties are in good agreement with previous numerical results. In addition, the formal joint inversion of hydrogeological and geomechanical data provides measures of the estimation uncertainty.« less

Thrust augmentation nozzle (TAN) concept for rocket engine booster applications

NASA Astrophysics Data System (ADS)

Forde, Scott; Bulman, Mel; Neill, Todd

2006-07-01

Aerojet used the patented thrust augmented nozzle (TAN) concept to validate a unique means of increasing sea-level thrust in a liquid rocket booster engine. We have used knowledge gained from hypersonic Scramjet research to inject propellants into the supersonic region of the rocket engine nozzle to significantly increase sea-level thrust without significantly impacting specific impulse. The TAN concept overcomes conventional engine limitations by injecting propellants and combusting in an annular region in the divergent section of the nozzle. This injection of propellants at moderate pressures allows for obtaining high thrust at takeoff without overexpansion thrust losses. The main chamber is operated at a constant pressure while maintaining a constant head rise and flow rate of the main propellant pumps. Recent hot-fire tests have validated the design approach and thrust augmentation ratios. Calculations of nozzle performance and wall pressures were made using computational fluid dynamics analyses with and without thrust augmentation flow, resulting in good agreement between calculated and measured quantities including augmentation thrust. This paper describes the TAN concept, the test setup, test results, and calculation results.

Impulsive Injection for Compressor Stator Separation Control

NASA Technical Reports Server (NTRS)

Culley, Dennis E.; Braunscheidel, Edward P.; Bright, Michelle M.

2005-01-01

Flow control using impulsive injection from the suction surface of a stator vane has been applied in a low speed axial compressor. Impulsive injection is shown to significantly reduce separation relative to steady injection for vanes that were induced to separate by an increase in vane stagger angle of 4 degrees. Injected flow was applied to the airfoil suction surface using spanwise slots pitched in the streamwise direction. Injection was limited to the near-hub region, from 10 to 36 percent of span, to affect the dominant loss due to hub leakage flow. Actuation was provided externally using high-speed solenoid valves closely coupled to the vane tip. Variations in injected mass, frequency, and duty cycle are explored. The local corrected total pressure loss across the vane at the lower span region was reduced by over 20 percent. Additionally, low momentum fluid migrating from the hub region toward the tip was effectively suppressed resulting in an overall benefit which reduced corrected area averaged loss through the passage by 4 percent. The injection mass fraction used for impulsive actuation was typically less than 0.1 percent of the compressor through flow.

Design of a Coupled Thermoresponsive Hydrogel and Robotic System for Postinfarct Biomaterial Injection Therapy

PubMed Central

Fok, Kevin; Yoshizumi, Tomo; Park, Daewoo; Jiang, Hongbin; Schwartzman, David S.; Zenati, Marco A.; Uchibori, Takafumi

2016-01-01

Background In preclinical testing, ventricular wall injection of hydrogels has been shown to be effective in modulating ventricular remodeling and preserving cardiac function. For some approaches, early-stage clinical trials are under way. The hydrogel delivery method varies, with minimally invasive approaches being preferred. Endocardial injections carry a risk of hydrogel regurgitation into the circulation, and precise injection patterning is a challenge. An epicardial approach with a thermally gelling hydrogel through the subxiphoid pathway overcomes these disadvantages. Methods A relatively stiff, thermally responsive, injectable hydrogel based on N-isopropylacrylamide and N-vinylpyrrolidone (VP gel) was synthesized and characterized. VP gel thermal behavior was tuned to couple with a transepicardial injection robot, incorporating a cooling feature to achieve injectability. Ventricular wall injections of the optimized VP gel have been performed ex vivo and on beating porcine hearts. Results Thermal transition temperature, viscosity, and gelling time for the VP gel were manipulated by altering N-vinylpyrrolidone content. The target parameters for cooling in the robotic system were chosen by thermal modeling to support smooth, repeated injections on an ex vivo heart. Injections at predefined locations and depth were confirmed in an infarcted porcine model. Conclusions A coupled thermoresponsive hydrogel and robotic injection system incorporating a temperature-controlled injectate line was capable of targeted injections and amenable to use with a subxiphoid transepicardial approach for hydrogel injection after myocardial infarction. The confirmation of precise location and depth injections would facilitate a patient-specific planning strategy to optimize injection patterning to maximize the mechanical benefits of hydrogel placement. PMID:27154150

Multimodal assessment of spatial distribution of drug-tracer uptake by brain tissue after intra-arterial injections

NASA Astrophysics Data System (ADS)

Singh-Moon, Rajinder; Chaudhuri, Durba; Wang, Mei; Straubinger, Robert; Bigio, Irving J.; Joshi, Shailendra

2014-02-01

It is challenging to track the rapid changes in drug concentrations after intra-arterial (IA) administration to elucidate the pharmacokinetics of this method of drug delivery. Traditional pharmacokinetic parameters (such as protein binding) that are highly relevant to intravenous (IV) administration do not seem to apply to IA injections. Regional drug delivery is affected by the biomechanics of drug injection, resting blood flow, and local tissue extraction. In-vivo and ex-vivo, optical methods for spatial mapping of drug deposition can assist in visualizing drug distributions and aid in the screening of potential drugs and carrier candidates. We present a multimodal approach for the assessment of drug distribution in postmortem tissue specimens using diffuse reflectance spectroscopy, multispectral imaging, and confocal microscopy and demonstrate feasibility of distinguishing route of administration advantages of liposome-dye conjugate delivery. The results of this study suggest that insight on drug dynamics gained by this aggregated approach can be used to help screen and/or optimize potential drug candidates and drug delivery protocols.

Effect of the number and position of nozzle holes on in- and near-nozzle dynamic characteristics of diesel injection

DOE Office of Scientific and Technical Information (OSTI.GOV)

Moon, Seoksu; Gao, Yuan; Park, Suhan

Despite the fact that all modern diesel engines use multi-hole injectors, single-hole injectors are frequently used to understand the fundamental properties of high-pressure diesel injections due to their axisymmetric design of the injector nozzles. A multi-hole injector accommodates many holes around the nozzle axis to deliver adequate amount of fuel with small orifices. The off-axis arrangement of the multi-hole injectors significantly alters the inter- and near-nozzle flow patterns compared to those of the single-hole injectors. This study compares the transient needle motion and near-nozzle flow characteristics of the single- and multi-hole (3-hole and 6-hole) diesel injectors to understand how themore » difference in hole arrangement and number affects the initial flow development of the diesel injectors. A propagation-based X-ray phase-contrast imaging technique was applied to compare the transient needle motion and near-nozzle flow characteristics of the single- and multi-hole injectors. The comparisons were made by dividing the entire injection process by three sub-stages: opening-transient, quasi-steady and closing-transient. (C) 2015 Elsevier Ltd. All rights reserved.« less

Performance comparison of supersonic ejectors with different motive gas injection schemes applicable for flowing medium gas laser

NASA Astrophysics Data System (ADS)

Singhal, G.; Subbarao, P. M. V.; Mainuddin; Tyagi, R. K.; Dawar, A. L.

2017-05-01

A class of flowing medium gas lasers with low generator pressures employ supersonic flows with low cavity pressure and are primarily categorized as high throughput systems capable of being scaled up to MW class. These include; Chemical Oxygen Iodine Laser (COIL) and Hydrogen (Deuterium) Fluoride (HF/DF). The practicability of such laser systems for various applications is enhanced by exhausting the effluents directly to ambient atmosphere. Consequently, ejector based pressure recovery forms a potent configuration for open cycle operation. Conventionally these gas laser systems require at least two ejector stages with low pressure stage being more critical, since it directly entrains the laser media, and the ensuing perturbation of cavity flow, if any, may affect laser operation. Hence, the choice of plausible motive gas injection schemes viz., peripheral or central is a fluid dynamic issue of interest, and a parametric experimental performance comparison would be beneficial. Thus, the focus is to experimentally characterize the effect of variation in motive gas supply pressure, entrainment ratio, back pressure conditions, nozzle injection position operated together with a COIL device and discern the reasons for the behavior.

Flow Rates Measurement and Uncertainty Analysis in Multiple-Zone Water-Injection Wells from Fluid Temperature Profiles

PubMed Central

Reges, José E. O.; Salazar, A. O.; Maitelli, Carla W. S. P.; Carvalho, Lucas G.; Britto, Ursula J. B.

2016-01-01

This work is a contribution to the development of flow sensors in the oil and gas industry. It presents a methodology to measure the flow rates into multiple-zone water-injection wells from fluid temperature profiles and estimate the measurement uncertainty. First, a method to iteratively calculate the zonal flow rates using the Ramey (exponential) model was described. Next, this model was linearized to perform an uncertainty analysis. Then, a computer program to calculate the injected flow rates from experimental temperature profiles was developed. In the experimental part, a fluid temperature profile from a dual-zone water-injection well located in the Northeast Brazilian region was collected. Thus, calculated and measured flow rates were compared. The results proved that linearization error is negligible for practical purposes and the relative uncertainty increases as the flow rate decreases. The calculated values from both the Ramey and linear models were very close to the measured flow rates, presenting a difference of only 4.58 m³/d and 2.38 m³/d, respectively. Finally, the measurement uncertainties from the Ramey and linear models were equal to 1.22% and 1.40% (for injection zone 1); 10.47% and 9.88% (for injection zone 2). Therefore, the methodology was successfully validated and all objectives of this work were achieved. PMID:27420068

Development and optimization of SPE-HPLC-UV/ELSD for simultaneous determination of nine bioactive components in Shenqi Fuzheng Injection based on Quality by Design principles.

PubMed

Wang, Lu; Qu, Haibin

2016-03-01

A method combining solid phase extraction, high performance liquid chromatography, and ultraviolet/evaporative light scattering detection (SPE-HPLC-UV/ELSD) was developed according to Quality by Design (QbD) principles and used to assay nine bioactive compounds within a botanical drug, Shenqi Fuzheng Injection. Risk assessment and a Plackett-Burman design were utilized to evaluate the impact of 11 factors on the resolutions and signal-to-noise of chromatographic peaks. Multiple regression and Pareto ranking analysis indicated that the sorbent mass, sample volume, flow rate, column temperature, evaporator temperature, and gas flow rate were statistically significant (p < 0.05) in this procedure. Furthermore, a Box-Behnken design combined with response surface analysis was employed to study the relationships between the quality of SPE-HPLC-UV/ELSD analysis and four significant factors, i.e., flow rate, column temperature, evaporator temperature, and gas flow rate. An analytical design space of SPE-HPLC-UV/ELSD was then constructed by calculated Monte Carlo probability. In the presented approach, the operating parameters of sample preparation, chromatographic separation, and compound detection were investigated simultaneously. Eight terms of method validation, i.e., system-suitability tests, method robustness/ruggedness, sensitivity, precision, repeatability, linearity, accuracy, and stability, were accomplished at a selected working point. These results revealed that the QbD principles were suitable in the development of analytical procedures for samples in complex matrices. Meanwhile, the analytical quality and method robustness were validated by the analytical design space. The presented strategy provides a tutorial on the development of a robust QbD-compliant quantitative method for samples in complex matrices.

Compressor Stall Recovery Through Tip Injection Assessed

NASA Technical Reports Server (NTRS)

Suder, Ken L.

2001-01-01

Aerodynamic stability is a fundamental limit in the compressor design process. The development of robust techniques for increasing stability has several benefits: enabling higher loading and fewer blades, increasing safety throughout a mission, increasing tolerance to stage mismatch during part-speed operation and speed transients, and providing an opportunity to match stages at the compressor maximum efficiency point, thus reducing fuel burn. Mass injection upstream of the tip of a high-speed axial compressor rotor is a stability enhancement approach known to be effective in suppressing stall in tip-critical rotors if the injection is activated before stall occurs. This approach to stall suppression requires that a reliable stall warning system be available. Tests have recently been performed to assess whether steady injection can also be used to recover from fully developed stall. If mass injection is effective in recovering from stall quickly enough to avoid structural damage or loss of engine power, then a stall warning system may not be required. The stall recovery tests were performed on a transonic compressor rotor at its design tip speed of 1475 ft/sec using four injectors evenly spaced around the compressor case upstream of the rotor. The injectors were connected to an external air source. In an actual engine application, the injected air would be supplied with compressor bleed air. The injectors were isolated from the air source by a fast-acting butterfly valve. With the injectors turned off, the compressor was throttled into stall. Air injection was then activated with no change in throttle setting by opening the butterfly valve. The compressor recovered from stall at a fixed throttle setting with the aid of tip injection. The unsteady operating characteristic of the rotor was measured during these tests using high-response pressure sensors located upstream and downstream of the rotor. The figure shows the results, where the unsteady pressure and mass flow are superimposed on the steady operating characteristic. The total injected mass flow was equal to 1.3 percent of the compressor flow. The solid line with no solid squares on it denotes the operating point during the beginning of throttle closure and the initial drop into stall. The gray traces denote the operating point during an additional throttle closure that occurred over the next 1200 rotor revolutions (4 sec). The dashed line denotes the recovery from stall that occurred during 90 rotor revolutions (0.3 sec) after the injectors were activated with no change in throttle setting. Tip injection not only recovers the compressor from stall, but also restores the compressor to its pre-stall level of pressure rise. In contrast, standard stall recovery schemes such as compressor bleed, stator vane actuation, or engine throttle modulation result in a loss of pressure rise across the compressor, which results in a loss of engine power.

Reactive Transport Modeling of Induced Calcite Precipitation Reaction Fronts in Porous Media Using A Parallel, Fully Coupled, Fully Implicit Approach

NASA Astrophysics Data System (ADS)

Guo, L.; Huang, H.; Gaston, D.; Redden, G. D.; Fox, D. T.; Fujita, Y.

2010-12-01

Inducing mineral precipitation in the subsurface is one potential strategy for immobilizing trace metal and radionuclide contaminants. Generating mineral precipitates in situ can be achieved by manipulating chemical conditions, typically through injection or in situ generation of reactants. How these reactants transport, mix and react within the medium controls the spatial distribution and composition of the resulting mineral phases. Multiple processes, including fluid flow, dispersive/diffusive transport of reactants, biogeochemical reactions and changes in porosity-permeability, are tightly coupled over a number of scales. Numerical modeling can be used to investigate the nonlinear coupling effects of these processes which are quite challenging to explore experimentally. Many subsurface reactive transport simulators employ a de-coupled or operator-splitting approach where transport equations and batch chemistry reactions are solved sequentially. However, such an approach has limited applicability for biogeochemical systems with fast kinetics and strong coupling between chemical reactions and medium properties. A massively parallel, fully coupled, fully implicit Reactive Transport simulator (referred to as “RAT”) based on a parallel multi-physics object-oriented simulation framework (MOOSE) has been developed at the Idaho National Laboratory. Within this simulator, systems of transport and reaction equations can be solved simultaneously in a fully coupled, fully implicit manner using the Jacobian Free Newton-Krylov (JFNK) method with additional advanced computing capabilities such as (1) physics-based preconditioning for solution convergence acceleration, (2) massively parallel computing and scalability, and (3) adaptive mesh refinements for 2D and 3D structured and unstructured mesh. The simulator was first tested against analytical solutions, then applied to simulating induced calcium carbonate mineral precipitation in 1D columns and 2D flow cells as analogs to homogeneous and heterogeneous porous media, respectively. In 1D columns, calcium carbonate mineral precipitation was driven by urea hydrolysis catalyzed by urease enzyme, and in 2D flow cells, calcium carbonate mineral forming reactants were injected sequentially, forming migrating reaction fronts that are typically highly nonuniform. The RAT simulation results for the spatial and temporal distributions of precipitates, reaction rates and major species in the system, and also for changes in porosity and permeability, were compared to both laboratory experimental data and computational results obtained using other reactive transport simulators. The comparisons demonstrate the ability of RAT to simulate complex nonlinear systems and the advantages of fully coupled approaches, over de-coupled methods, for accurate simulation of complex, dynamic processes such as engineered mineral precipitation in subsurface environments.

Flow Injection Technique for Biochemical Analysis with Chemiluminescence Detection in Acidic Media

PubMed Central

Chen, Jing; Fang, Yanjun

2007-01-01

A review with 90 references is presented to show the development of acidic chemiluminescence methods for biochemical analysis by use of flow injection technique in the last 10 years. A brief discussion of both the chemiluminescence and flow injection technique is given. The proposed methods for biochemical analysis are described and compared according to the used chemiluminescence system.

Separation Control in a Multistage Compressor Using Impulsive Surface Injection

NASA Technical Reports Server (NTRS)

Wundrow, David W.; Braunscheidel, Edward P.; Culley, Dennis E.; Bright, Michelle M.

2006-01-01

Control of flow separation using impulsive surface injection is investigated within the multistage environment of a low speed axial-flow compressor. Measured wake profiles behind a set of embedded stator vanes treated with suction-surface injection indicate significant reduction in flow separation at a variety of injection-pulse repetition rates and durations. The corresponding total pressure losses across the vanes reveal a bank of repetition rates at each pulse duration where the separation control remains nearly complete. This persistence allows for demands on the injected-mass delivery system to be economized while still achieving effective flow control. The response of the stator-vane boundary layers to infrequently applied short injection pulses is described in terms of the periodic excitation of turbulent strips whose growth and propagation characteristics dictate the lower bound on the band of optimal pulse repetition rates. The eventual falloff in separation control at higher repetition rates is linked to a competition between the benefits of pulse-induced mixing and the aggravation caused by the periodic introduction of low-momentum fluid. Use of these observations for impulsive actuator design is discussed and their impact on modeling the time-average effect of impulsive surface injection for multistage steady-flow simulation is considered.

Flow processes in electric discharge drivers

NASA Technical Reports Server (NTRS)

Baganoff, D.

1975-01-01

The performance of an electric discharge shock tube is discussed from the point of view that the conditions at the sonic station are the primary controlling variables (likewise in comparing designs), and that the analysis of the flow on either side of the sonic station should be done separately. The importance of considering mass-flow rate in matching a given driver design to the downstream flow required for a particular shock-wave speed is stressed. It is shown that a driver based on the principle of liquid injection (of H2) is superior to one based on the Ludwieg tube, because of the greater mass-flow rate and the absence of a massive diaphragm.

Design for testability and diagnosis at the system-level

NASA Technical Reports Server (NTRS)

Simpson, William R.; Sheppard, John W.

1993-01-01

The growing complexity of full-scale systems has surpassed the capabilities of most simulation software to provide detailed models or gate-level failure analyses. The process of system-level diagnosis approaches the fault-isolation problem in a manner that differs significantly from the traditional and exhaustive failure mode search. System-level diagnosis is based on a functional representation of the system. For example, one can exercise one portion of a radar algorithm (the Fast Fourier Transform (FFT) function) by injecting several standard input patterns and comparing the results to standardized output results. An anomalous output would point to one of several items (including the FFT circuit) without specifying the gate or failure mode. For system-level repair, identifying an anomalous chip is sufficient. We describe here an information theoretic and dependency modeling approach that discards much of the detailed physical knowledge about the system and analyzes its information flow and functional interrelationships. The approach relies on group and flow associations and, as such, is hierarchical. Its hierarchical nature allows the approach to be applicable to any level of complexity and to any repair level. This approach has been incorporated in a product called STAMP (System Testability and Maintenance Program) which was developed and refined through more than 10 years of field-level applications to complex system diagnosis. The results have been outstanding, even spectacular in some cases. In this paper we describe system-level testability, system-level diagnoses, and the STAMP analysis approach, as well as a few STAMP applications.

Heat tracer test in an alluvial aquifer: Field experiment and inverse modelling

NASA Astrophysics Data System (ADS)

Klepikova, Maria; Wildemeersch, Samuel; Hermans, Thomas; Jamin, Pierre; Orban, Philippe; Nguyen, Frédéric; Brouyère, Serge; Dassargues, Alain

2016-09-01

Using heat as an active tracer for aquifer characterization is a topic of increasing interest. In this study, we investigate the potential of using heat tracer tests for characterization of a shallow alluvial aquifer. A thermal tracer test was conducted in the alluvial aquifer of the Meuse River, Belgium. The tracing experiment consisted in simultaneously injecting heated water and a dye tracer in an injection well and monitoring the evolution of groundwater temperature and tracer concentration in the pumping well and in measurement intervals. To get insights in the 3D characteristics of the heat transport mechanisms, temperature data from a large number of observation wells closely spaced along three transects were used. Temperature breakthrough curves in observation wells are contrasted with what would be expected in an ideal layered aquifer. They reveal strongly unequal lateral and vertical components of the transport mechanisms. The observed complex behavior of the heat plume is explained by the groundwater flow gradient on the site and heterogeneities in the hydraulic conductivity field. Moreover, due to high injection temperatures during the field experiment a temperature-induced fluid density effect on heat transport occurred. By using a flow and heat transport numerical model with variable density coupled with a pilot point approach for inversion of the hydraulic conductivity field, the main preferential flow paths were delineated. The successful application of a field heat tracer test at this site suggests that heat tracer tests is a promising approach to image hydraulic conductivity field. This methodology could be applied in aquifer thermal energy storage (ATES) projects for assessing future efficiency that is strongly linked to the hydraulic conductivity variability in the considered aquifer.

Delineation of Groundwater Flow Pathway in Fractured Bedrock Using Nano-Iron Tracer Test in the Sealed Well

NASA Astrophysics Data System (ADS)

Chuang, Po-Yu; Chia, Yeeping; Chiu, Yung-Chia; Liou, Ya-Hsuan; Teng, Mao-Hua; Liu, Ching-Yi; Lee, Tsai-Ping

2016-04-01

Deterministic delineation of the preferential flow paths and their hydraulic properties are desirable for developing hydrogeological conceptual models in bedrock aquifers. In this study, we proposed using nanoscale zero-valent iron (nZVI) as a tracer to characterize the fractured connectivity and hydraulic properties. Since nZVI particles are magnetic, we designed a magnet array to attract the arriving nZVI particles in the observation well for identifying the location of incoming tracer. This novel approach was examined at two experiment wells with well hydraulic connectivity in a hydrogeological research station in the fractured aquifer. Heat-pulse flowmeter test was used to detect the vertical distribution of permeable zones in the borehole, providing the design basis of tracer test. Then, the less permeable zones in the injection well were sealed by casing to prevent the injected nZVI particles from being stagnated at the bottom hole. Afterwards, hydraulic test was implemented to examine the hydraulic connectivity between two wells. When nZVI slurry was released in the injection well, they could migrate through connected permeable fractures to the observation well. A breakthrough curve was obtained by the fluid conductivity sensor in the observation well, indicating the arrival of nZVI slurry. The iron nanoparticles that were attracted to the magnets in the observation well provide the quantitative information to locate the position of tracer inlet, which corroborates well with the depth of a permeable zone delineated by the flowmeter. Finally, the numerical method was utilized to simulate the process of tracer migration. This article demonstrates that nano-iron tracer test can be a promising approach for characterizing connectivity patterns and transmissivities of the flow paths in the fractured rock.

Impact of the shape of the implantable ports on their efficiency of flow (injection and flushing)

PubMed Central

Guiffant, Gérard; Flaud, Patrice; Durussel, Jean Jacques; Merckx, Jacques

2014-01-01

Now widely used, totally implantable venous access devices allow mid- and long-term, frequent, repeated, or continuous injection of therapeutic products by vascular, cavitary, or perineural access. The effective flushing of these devices is a key factor that ensures their long-lasting use. We present experimental results and a numerical simulation to demonstrate that the implementation of rounded edge wall cavities improves flushing efficiency. We use the same approaches to suggest that the deposit amount may be reduced by the use of rounded edge wall cavities. PMID:25258561

A portable battery-powered flow injection monitor for the in situ analysis of nitrate in natural waters

PubMed Central

Blundell, N. J.; Hopkins, A.; Worsfold, P. J.; Casey, H.

1993-01-01

The design and performance of a portable, automated flow injection (FI)-based photometric monitor are described. The system is controlled by an in-house microcomputer system that enables the monitor (including a solid state detector) to operate from a 12 V battery supply. The monitor uses the cadmium reduction/diazotization method to analyse for nitrate with a linear range of 0 to 12 mg l-1 and a limit of detection of 0.05 mg l-1 (NO3-N). The hardware and software design, monitor performance and results obtained during unattended operation are presented. PMID:18924971

An injectable elastin-based gene delivery platform for dose-dependent modulation of angiogenesis and inflammation for critical limb ischemia.

PubMed

Dash, Biraja C; Thomas, Dilip; Monaghan, Michael; Carroll, Oliver; Chen, Xizhe; Woodhouse, Kimberly; O'Brien, Timothy; Pandit, Abhay

2015-10-01

Critical limb ischemia is a major clinical problem. Despite rigorous treatment regimes, there has been only modest success in reducing the rate of amputations in affected patients. Reduced level of blood flow and enhanced inflammation are the two major pathophysiological changes that occur in the ischemic tissue. The objective of this study was to develop a controlled dual gene delivery system capable of delivering therapeutic plasmid eNOS and IL-10 in a temporal manner. In order to deliver multiple therapeutic genes, an elastin-like polypeptide (ELP) based injectable system was designed. The injectable system was comprised of hollow spheres and an in situ-forming gel scaffold of elastin-like polypeptide capable of carrying gene complexes, with an extended manner release profile. In addition, the ELP based injectable system was used to deliver human eNOS and IL-10 therapeutic genes in vivo. A subcutaneous dose response study showed enhanced blood vessel density in the treatment groups of eNOS (20 μg) and IL-10 (10 μg)/eNOS (20 μg) and reduced inflammation with IL-10 (10 μg) alone. Next, we carried out a hind-limb ischemia model comparing the efficacy of the following interventions; Saline; IL-10, eNOS and IL-10/eNOS. The selected dose of eNOS, exhibited enhanced angiogenesis. IL-10 treatment groups showed reduction in the level of inflammatory cells. Furthermore, we demonstrated that eNOS up-regulated major proangiogenic growth factors such as vascular endothelial growth factors, platelet derived growth factor B, and fibroblast growth factor 1, which may explain the mechanism of this approach. These factors help in formation of a stable vascular network. Thus, ELP injectable system mediating non-viral delivery of human IL10-eNOS is a promising therapy towards treating limb ischemia. Copyright © 2015 Elsevier Ltd. All rights reserved.

Microfluidic Injector Models Based on Artificial Neural Networks

DTIC Science & Technology

2005-06-15

medicine, and chemistry [1], [2]. They generally perform chemical analysis involving sample preparation, mixing , reaction, injection, separation analysis...algorithms have been validated against many ex- periments found in the literature demonstrating microfluidic mixing , joule heating, injection, and...385 [7] K. Seiler, Z. H. Fan, K. Fluri, and D. J. Harrison, “ Electroosmotic pump- ing and valveless control of fluid flow within a manifold of

Investigation of nozzle flow and cavitation characteristics in a diesel injector.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Som, S.; Ramirez, A.; Aggarwal, S.

2010-04-01

Cavitation and turbulence inside a diesel injector play a critical role in primary spray breakup and development processes. The study of cavitation in realistic injectors is challenging, both theoretically and experimentally, since the associated two-phase flow field is turbulent and highly complex, characterized by large pressure gradients and small orifice geometries. We report herein a computational investigation of the internal nozzle flow and cavitation characteristics in a diesel injector. A mixture based model in FLUENT V6.2 software is employed for simulations. In addition, a new criterion for cavitation inception based on the total stress is implemented, and its effectiveness inmore » predicting cavitation is evaluated. Results indicate that under realistic diesel engine conditions, cavitation patterns inside the orifice are influenced by the new cavitation criterion. Simulations are validated using the available two-phase nozzle flow data and the rate of injection measurements at various injection pressures (800-1600 bar) from the present study. The computational model is then used to characterize the effects of important injector parameters on the internal nozzle flow and cavitation behavior, as well as on flow properties at the nozzle exit. The parameters include injection pressure, needle lift position, and fuel type. The propensity of cavitation for different on-fleet diesel fuels is compared with that for n-dodecane, a diesel fuel surrogate. Results indicate that the cavitation characteristics of n-dodecane are significantly different from those of the other three fuels investigated. The effect of needle movement on cavitation is investigated by performing simulations at different needle lift positions. Cavitation patterns are seen to shift dramatically as the needle lift position is changed during an injection event. The region of significant cavitation shifts from top of the orifice to bottom of the orifice as the needle position is changed from fully open (0.275 mm) to nearly closed (0.1 mm), and this behavior can be attributed to the effect of needle position on flow patterns upstream of the orifice. The results demonstrate the capability of the cavitation model to predict cavitating nozzle flows in realistic diesel injectors and provide boundary conditions, in terms of vapor fraction, velocity, and turbulence parameters at the nozzle exit, which can be coupled with the primary breakup simulation.« less

Cell-specific transmembrane injection of molecular cargo with gold nanoparticle-generated transient plasmonic nanobubbles

PubMed Central

Lukianova-Hleb, Ekaterina Y.; Wagner, Daniel S.; Brenner, Malcolm K.; Lapotko, Dmitri O.

2012-01-01

Optimal cell therapies require efficient, selective and rapid delivery of molecular cargo into target cells without compromising their viability. Achieving these goals ex vivo in bulk heterogeneous multi-cell systems such as human grafts is impeded by low selectivity and speed of cargo delivery and by significant damage to target and non-target cells. We have developed a cell level approach for selective and guided trans-membrane injection of extracellular cargo into specific target cells using transient plasmonic nanobubbles (PNB) as cell-specific nano-injectors. As a technical platform for this method we developed a laser flow cell processing system. The PNB injection method and flow system were tested in heterogeneous cell suspensions of target and non-target cells for delivery of Dextran-FITC dye into squamous cell carcinoma HN31 cells and transfection of human T-cells with a green fluorescent protein-encoding plasmid. In both models the method demonstrated single cell type selectivity, high efficacy of delivery (96% both for HN31 cells T-cells), speed of delivery (nanoseconds) and viability of treated target cells (96% for HN31 cells and 75% for T-cells). The PNB injection method may therefore be beneficial for real time processing of human grafts without removal of physiologically important cells. PMID:22521612

Cell-specific transmembrane injection of molecular cargo with gold nanoparticle-generated transient plasmonic nanobubbles.

PubMed

Lukianova-Hleb, Ekaterina Y; Wagner, Daniel S; Brenner, Malcolm K; Lapotko, Dmitri O

2012-07-01

Optimal cell therapies require efficient, selective and rapid delivery of molecular cargo into target cells without compromising their viability. Achieving these goals ex vivo in bulk heterogeneous multi-cell systems such as human grafts is impeded by low selectivity and speed of cargo delivery and by significant damage to target and non-target cells. We have developed a cell level approach for selective and guided transmembrane injection of extracellular cargo into specific target cells using transient plasmonic nanobubbles (PNB) as cell-specific nano-injectors. As a technical platform for this method we developed a laser flow cell processing system. The PNB injection method and flow system were tested in heterogeneous cell suspensions of target and non-target cells for delivery of Dextran-FITC dye into squamous cell carcinoma HN31 cells and transfection of human T-cells with a green fluorescent protein-encoding plasmid. In both models the method demonstrated single cell type selectivity, high efficacy of delivery (96% both for HN31 cells T-cells), speed of delivery (nanoseconds) and viability of treated target cells (96% for HN31 cells and 75% for T-cells). The PNB injection method may therefore be beneficial for real time processing of human grafts without removal of physiologically important cells. Copyright © 2012 Elsevier Ltd. All rights reserved.

Injectant mole-fraction imaging in compressible mixing flows using planar laser-induced iodine fluorescence

NASA Technical Reports Server (NTRS)

Hartfield, Roy J., Jr.; Abbitt, John D., III; Mcdaniel, James C.

1989-01-01

A technique is described for imaging the injectant mole-fraction distribution in nonreacting compressible mixing flow fields. Planar fluorescence from iodine, seeded into air, is induced by a broadband argon-ion laser and collected using an intensified charge-injection-device array camera. The technique eliminates the thermodynamic dependence of the iodine fluorescence in the compressible flow field by taking the ratio of two images collected with identical thermodynamic flow conditions but different iodine seeding conditions.

Monitoring CO2 invasion processes at the pore scale using geological labs on chip.

PubMed

Morais, S; Liu, N; Diouf, A; Bernard, D; Lecoutre, C; Garrabos, Y; Marre, S

2016-09-21

In order to investigate at the pore scale the mechanisms involved during CO2 injection in a water saturated pore network, a series of displacement experiments is reported using high pressure micromodels (geological labs on chip - GLoCs) working under real geological conditions (25 < T (°C) < 75 and 4.5 < p (MPa) < 8). The experiments were focused on the influence of three experimental parameters: (i) the p, T conditions, (ii) the injection flow rates and (iii) the pore network characteristics. By using on-chip optical characterization and imaging approaches, the CO2 saturation curves as a function of either time or the number of pore volume injected were determined. Three main mechanisms were observed during CO2 injection, namely, invasion, percolation and drying, which are discussed in this paper. Interestingly, besides conventional mechanisms, two counterintuitive situations were observed during the invasion and drying processes.

Axisymmetric flows from fluid injection into a confined porous medium

NASA Astrophysics Data System (ADS)

Guo, Bo; Zheng, Zhong; Celia, Michael A.; Stone, Howard A.

2016-02-01

We study the axisymmetric flows generated from fluid injection into a horizontal confined porous medium that is originally saturated with another fluid of different density and viscosity. Neglecting the effects of surface tension and fluid mixing, we use the lubrication approximation to obtain a nonlinear advection-diffusion equation that describes the time evolution of the sharp fluid-fluid interface. The flow behaviors are controlled by two dimensionless groups: M, the viscosity ratio of displaced fluid relative to injected fluid, and Γ, which measures the relative importance of buoyancy and fluid injection. For this axisymmetric geometry, the similarity solution involving R2/T (where R is the dimensionless radial coordinate and T is the dimensionless time) is an exact solution to the nonlinear governing equation for all times. Four analytical expressions are identified as asymptotic approximations (two of which are new solutions): (i) injection-driven flow with the injected fluid being more viscous than the displaced fluid (Γ ≪ 1 and M < 1) where we identify a self-similar solution that indicates a parabolic interface shape; (ii) injection-driven flow with injected and displaced fluids of equal viscosity (Γ ≪ 1 and M = 1), where we find a self-similar solution that predicts a distinct parabolic interface shape; (iii) injection-driven flow with a less viscous injected fluid (Γ ≪ 1 and M > 1) for which there is a rarefaction wave solution, assuming that the Saffman-Taylor instability does not occur at the reservoir scale; and (iv) buoyancy-driven flow (Γ ≫ 1) for which there is a well-known self-similar solution corresponding to gravity currents in an unconfined porous medium [S. Lyle et al. "Axisymmetric gravity currents in a porous medium," J. Fluid Mech. 543, 293-302 (2005)]. The various axisymmetric flows are summarized in a Γ-M regime diagram with five distinct dynamic behaviors including the four asymptotic regimes and an intermediate regime. The implications of the regime diagram are discussed using practical engineering projects of geological CO2 sequestration, enhanced oil recovery, and underground waste disposal.

Study of compressible turbulent flows in supersonic environment by large-eddy simulation

NASA Astrophysics Data System (ADS)

Genin, Franklin

The numerical resolution of turbulent flows in high-speed environment is of fundamental importance but remains a very challenging problem. First, the capture of strong discontinuities, typical of high-speed flows, requires the use of shock-capturing schemes, which are not adapted to the resolution of turbulent structures due to their intrinsic dissipation. On the other hand, low-dissipation schemes are unable to resolve shock fronts and other sharp gradients without creating high amplitude numerical oscillations. Second, the nature of turbulence in high-speed flows differs from its incompressible behavior, and, in the context of Large-Eddy Simulation, the subgrid closure must be adapted to the modeling of compressibility effects and shock waves on turbulent flows. The developments described in this thesis are two-fold. First, a state of the art closure approach for LES is extended to model subgrid turbulence in compressible flows. The energy transfers due to compressible turbulence and the diffusion of turbulent kinetic energy by pressure fluctuations are assessed and integrated in the Localized Dynamic ksgs model. Second, a hybrid numerical scheme is developed for the resolution of the LES equations and of the model transport equation, which combines a central scheme for turbulent resolutions to a shock-capturing method. A smoothness parameter is defined and used to switch from the base smooth solver to the upwind scheme in regions of discontinuities. It is shown that the developed hybrid methodology permits a capture of shock/turbulence interactions in direct simulations that agrees well with other reference simulations, and that the LES methodology effectively reproduces the turbulence evolution and physical phenomena involved in the interaction. This numerical approach is then employed to study a problem of practical importance in high-speed mixing. The interaction of two shock waves with a high-speed turbulent shear layer as a mixing augmentation technique is considered. It is shown that the levels of turbulence are increased through the interaction, and that the mixing is significantly improved in this flow configuration. However, the region of increased mixing is found to be localized to a region close to the impact of the shocks, and that the statistical levels of turbulence relax to their undisturbed levels some short distance downstream of the interaction. The present developments are finally applied to a practical configuration relevant to scramjet injection. The normal injection of a sonic jet into a supersonic crossflow is considered numerically, and compared to the results of an experimental study. A fair agreement in the statistics of mean and fluctuating velocity fields is obtained. Furthermore, some of the instantaneous flow structures observed in experimental visualizations are identified in the present simulation. The dynamics of the interaction for the reference case, based on the experimental study, as well as for a case of higher freestream Mach number and a case of higher momentum ratio, are examined. The classical instantaneous vortical structures are identified, and their generation mechanisms, specific to supersonic flow, are highlighted. Furthermore, two vortical structures, recently revealed in low-speed jets in crossflow but never documented for high-speed flows, are identified during the flow evolution.

Finite element flow analysis; Proceedings of the Fourth International Symposium on Finite Element Methods in Flow Problems, Chuo University, Tokyo, Japan, July 26-29, 1982

NASA Astrophysics Data System (ADS)

Kawai, T.

Among the topics discussed are the application of FEM to nonlinear free surface flow, Navier-Stokes shallow water wave equations, incompressible viscous flows and weather prediction, the mathematical analysis and characteristics of FEM, penalty function FEM, convective, viscous, and high Reynolds number FEM analyses, the solution of time-dependent, three-dimensional and incompressible Navier-Stokes equations, turbulent boundary layer flow, FEM modeling of environmental problems over complex terrain, and FEM's application to thermal convection problems and to the flow of polymeric materials in injection molding processes. Also covered are FEMs for compressible flows, including boundary layer flows and transonic flows, hybrid element approaches for wave hydrodynamic loadings, FEM acoustic field analyses, and FEM treatment of free surface flow, shallow water flow, seepage flow, and sediment transport. Boundary element methods and FEM computational technique topics are also discussed. For individual items see A84-25834 to A84-25896

Tablet coating by injection molding technology - Optimization of coating formulation attributes and coating process parameters.

PubMed

Desai, Parind M; Puri, Vibha; Brancazio, David; Halkude, Bhakti S; Hartman, Jeremy E; Wahane, Aniket V; Martinez, Alexander R; Jensen, Keith D; Harinath, Eranda; Braatz, Richard D; Chun, Jung-Hoon; Trout, Bernhardt L

2018-01-01

We developed and evaluated a solvent-free injection molding (IM) coating technology that could be suitable for continuous manufacturing via incorporation with IM tableting. Coating formulations (coating polymers and plasticizers) were prepared using hot-melt extrusion and screened via stress-strain analysis employing a universal testing machine. Selected coating formulations were studied for their melt flow characteristics. Tablets were coated using a vertical injection molding unit. Process parameters like softening temperature, injection pressure, and cooling temperature played a very important role in IM coating processing. IM coating employing polyethylene oxide (PEO) based formulations required sufficient room humidity (>30% RH) to avoid immediate cracks, whereas other formulations were insensitive to the room humidity. Tested formulations based on Eudrajit E PO and Kollicoat IR had unsuitable mechanical properties. Three coating formulations based on hydroxypropyl pea starch, PEO 1,000,000 and Opadry had favorable mechanical (<700MPa Young's modulus, >35% elongation, >95×10 4 J/m 3 toughness) and melt flow (>0.4g/min) characteristics, that rendered acceptable IM coats. These three formulations increased the dissolution time by 10, 15 and 35min, respectively (75% drug release), compared to the uncoated tablets (15min). Coated tablets stored in several environmental conditions remained stable to cracking for the evaluated 8-week time period. Copyright © 2017 Elsevier B.V. All rights reserved.

10 CFR Appendix E to Part 50 - Emergency Planning and Preparedness for Production and Utilization Facilities

Code of Federal Regulations, 2011 CFR

2011-01-01

... could communicate with a safety system. In this case, appropriate isolation devices would be required at..., feedwater flow, and reactor power; (2) Safety injection: Reactor core isolation cooling flow, high-pressure... data points identified in the ERDS Data Point Library 9 (site specific data base residing on the ERDS...

10 CFR Appendix E to Part 50 - Emergency Planning and Preparedness for Production and Utilization Facilities

Code of Federal Regulations, 2010 CFR

2010-01-01

... could communicate with a safety system. In this case, appropriate isolation devices would be required at..., feedwater flow, and reactor power; (2) Safety injection: Reactor core isolation cooling flow, high-pressure... data points identified in the ERDS Data Point Library 9 (site specific data base residing on the ERDS...

THE EFFECT OF WATER (VAPOR-PHASE) AND CARBON ON ELEMENTAL MERCURY REMOVAL IN A FLOW REACTOR

EPA Science Inventory

The paper gives results of studying the effect of vapor-phase moisture on elemental mercury (Hgo) removal by activated carbon (AC) in a flow reactor. tests involved injecting AC into both a dry and a 4% moisture nitrogen (N2) /Hgo gas stream. A bituminous-coal-based AC (Calgon WP...

Post-injection Multiphase Flow Modeling and Risk Assessments for Subsurface CO2 Storage in Naturally Fractured Reservoirs

NASA Astrophysics Data System (ADS)

Jin, G.

2015-12-01

Subsurface storage of carbon dioxide in geological formations is widely regarded as a promising tool for reducing global atmospheric CO2 emissions. Successful geologic storage for sequestrated carbon dioxides must prove to be safe by means of risk assessments including post-injection analysis of injected CO2 plumes. Because fractured reservoirs exhibit a higher degree of heterogeneity, it is imperative to conduct such simulation studies in order to reliably predict the geometric evolution of plumes and risk assessment of post CO2injection. The research has addressed the pressure footprint of CO2 plumes through the development of new techniques which combine discrete fracture network and stochastic continuum modeling of multiphase flow in fractured geologic formations. A subsequent permeability tensor map in 3-D, derived from our preciously developed method, can accurately describe the heterogeneity of fracture reservoirs. A comprehensive workflow integrating the fracture permeability characterization and multiphase flow modeling has been developed to simulate the CO2plume migration and risk assessments. A simulated fractured reservoir model based on high-priority geological carbon sinks in central Alabama has been employed for preliminary study. Discrete fracture networks were generated with an NE-oriented regional fracture set and orthogonal NW-fractures. Fracture permeability characterization revealed high permeability heterogeneity with an order of magnitude of up to three. A multiphase flow model composed of supercritical CO2 and saline water was then applied to predict CO2 plume volume, geometry, pressure footprint, and containment during and post injection. Injection simulation reveals significant permeability anisotropy that favors development of northeast-elongate CO2 plumes, which are aligned with systematic fractures. The diffusive spreading front of the CO2 plume shows strong viscous fingering effects. Post-injection simulation indicates significant upward lateral spreading of CO2 resulting in accumulation of CO2 directly under the seal unit because of its buoyancy and strata-bound vertical fractures. Risk assessment shows that lateral movement of CO2 along interconnected fractures requires widespread seals with high integrity to confine the injected CO2.

Injection and swirl driven flowfields in solid and liquid rocket motors

NASA Astrophysics Data System (ADS)

Vyas, Anand B.

In this work, we seek approximate analytical solutions to describe the bulk flow motion in certain types of solid and liquid rocket motors. In the case of an idealized solid rocket motor, a cylindrical double base propellant grain with steady regression rate is considered. The well known inviscid profile determined by Culick is extended here to include the effects of viscosity and steady grain regression. The approximate analytical solution for the cold flow is obtained from similarity principles, perturbation methods and the method of variation of parameters. The velocity, vorticity, pressure gradient and the shear stress distributions are determined and interpreted for different rates of wall regression and injection Reynolds number. The liquid propellant rocket engine considered here is based on a novel design that gives rise to a cyclonic flow. The resulting bidirectional motion is triggered by the tangential injection of an oxidizer just upstream of the chamber nozzle. Velocity, vorticity and pressure gradient distributions are determined for the bulk gas dynamics using a non-reactive inviscid model. Viscous corrections are then incorporated to explain the formation of a forced vortex near the core. Our results compare favorably with numerical simulations and experimental measurements obtained by other researchers. They also indicate that the bidirectional vortex in a cylindrical chamber is a physical solution of the Euler equations. In closing, we investigate the possibility of multi-directional flow behavior as predicted by Euler's equation and as reported recently in laboratory experiments.

Application of direct-injection detector integrated with the multi-pumping flow system to chemiluminescence determination of the total polyphenol index.

PubMed

Nalewajko-Sieliwoniuk, Edyta; Iwanowicz, Magdalena; Kalinowski, Sławomir; Kojło, Anatol

2016-03-10

In this work, we present a novel chemiluminescence (CL) method based on direct-injection detector (DID) integrated with the multi-pumping flow system (MPFS) to chemiluminescence determination of the total polyphenol index. In this flow system, the sample and the reagents are injected directly into the cone-shaped detection cell placed in front of the photomultiplier window. Such construction of the detection chamber allows for fast measurement of the CL signal in stopped-flow conditions immediately after mixing the reagents. The proposed DID-CL-MPFS method is based on the chemiluminescence of nanocolloidal manganese(IV)-hexametaphosphate-ethanol system. The application of ethanol as a sensitizer, eliminated the use of carcinogenic formaldehyde. Under the optimized experimental conditions, the chemiluminescence intensities are proportional to the concentration of gallic acid in the range from 5 to 350 ng mL(-1). The DID-CL-MPFS method offers a number of advantages, including low limit of detection (0.80 ng mL(-1)), high precision (RSD = 3.3%) and high sample throughput (144 samples h(-1)) as well as low consumption of reagents, energy and low waste generation. The proposed method has been successfully applied to determine the total polyphenol index (expressed as gallic acid equivalent) in a variety of plant-derived food samples (wine, tea, coffee, fruit and vegetable juices, herbs, spices). Copyright © 2016 Elsevier B.V. All rights reserved.

Thermal Drawdown-Induced Flow Channeling in Fractured Geothermal Reservoirs

DOE PAGES

Fu, Pengcheng; Hao, Yue; Walsh, Stuart D. C.; ...

2015-06-30

In this paper, we investigate the flow-channeling phenomenon caused by thermal drawdown in fractured geothermal reservoirs. A discrete fracture network-based, fully coupled thermal–hydrological–mechanical simulator is used to study the interactions between fluid flow, temperature change, and the associated rock deformation. The responses of a number of randomly generated 2D fracture networks that represent a variety of reservoir characteristics are simulated with various injection-production well distances. We find that flow channeling, namely flow concentration in cooled zones, is the inevitable fate of all the scenarios evaluated. We also identify a secondary geomechanical mechanism caused by the anisotropy in thermal stress thatmore » counteracts the primary mechanism of flow channeling. This new mechanism tends, to some extent, to result in a more diffuse flow distribution, although it is generally not strong enough to completely reverse flow channeling. We find that fracture intensity substantially affects the overall hydraulic impedance of the reservoir but increasing fracture intensity generally does not improve heat production performance. Finally, increasing the injection-production well separation appears to be an effective means to prolong the production life of a reservoir.« less

Multicommuted flow injection method for fast photometric determination of phenolic compounds in commercial virgin olive oil samples.

PubMed

Lara-Ortega, Felipe J; Sainz-Gonzalo, Francisco J; Gilbert-López, Bienvenida; García-Reyes, Juan F; Molina-Díaz, Antonio

2016-01-15

A multicommuted flow injection method has been developed for the determination of phenolic species in virgin olive oil samples. The method is based on the inhibitory effect of antioxidants on a stable and colored radical cation formation from the colorless compound N,N-dimethyl-p-phenylenediamine (DMPD(•+)) in acidic medium in the presence of Fe(III) as oxidant. The signal inhibition by phenolic species and other antioxidants is proportional to their concentration in the olive oil sample. Absorbance was recorded at 515nm by means of a modular fiber optic spectrometer. Oleuropein was used as the standard for phenols determination and 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (trolox) was the reference standard used for total antioxidant content calculation. Linear response was observed within the range of 250-1000mg/kg oleuropein, which was in accordance with phenolic contents observed in commercial extra virgin olive oil in the present study. Fast and low-volume liquid-liquid extraction of the samples using 60% MeOH was made previous to their insertion in the flow multicommuted system. The five three-way solenoid valves used for multicommuted liquid handling were controlled by a homemade electronic interface and Java-written software. The proposed approach was applied to different commercial extra virgin olive oil samples and the results were consistent with those obtained by the Folin Ciocalteu (FC) method. Total time for the sample preparation and the analysis required in the present approach can be drastically reduced: the throughput of the present analysis is 8 samples/h in contrast to 1sample/h of the conventional FC method. The present method is easy to implement in routine analysis and can be regarded as a feasible alternative to FC method. Copyright © 2015 Elsevier B.V. All rights reserved.

Advancement of In-Flight Alumina Powder Spheroidization Process with Water Droplet Injection Using a Small Power DC-RF Hybrid Plasma Flow System

NASA Astrophysics Data System (ADS)

Jang, Juyong; Takana, Hidemasa; Park, Sangkyu; Nishiyama, Hideya

2012-09-01

The correlation between plasma thermofluid characteristics and alumina powder spheroidization processes with water droplet injection using a small power DC-RF hybrid plasma flow system was experimentally clarified. Micro-sized water droplets with a low water flow rate were injected into the tail of thermal plasma flow so as not to disturb the plasma flow directly. Injected water droplets were vaporized in the thermal plasma flow and were transported upstream in the plasma flow to the torch by the backflow. After dissociation of water, the production of hydrogen was detected by the optical emission spectroscopy in the downstream RF plasma flow. The emission area of the DC plasma jet expanded and elongated in the vicinity of the RF coils. Additionally, the emission area of RF plasma flow enlarged and was visible as red emission in the downstream RF plasma flow in the vicinity below the RF coils due to hydrogen production. Therefore, the plasma flow mixed with produced hydrogen increased the plasma enthalpy and the highest spheroidization rate of 97% was obtained at a water flow rate of 15 Sm l/min and an atomizing gas flow rate of 8 S l/min using a small power DC-RF hybrid plasma flow system.

Flow friction of the turbulent coolant flow in cryogenic porous cables

NASA Technical Reports Server (NTRS)

Hendricks, R. C.; Yeroshenko, V. M.; Zaichik, L. I.; Yanovsky, L. S.

1979-01-01

Considered are cryogenic power transmission cables with porous cores. Calculations of the turbulent coolant flow with injection or suction through the porous wall are presented within the framework of a two-layer model. Universal velocity profiles were obtained for the viscous sublayer and flow core. Integrating the velocity profile, the law of flow friction in the pipe with injection has been derived for the case when there is a tangential injection velocity component. The effect of tangential velocity on the relative law of flow friction is analyzed. The applicability of the Prandtl model to the problem under study is discussed. It is shown that the error due to the acceptance of the model increases with the injection parameter and at lower Reynolds numbers; under these circumstances, the influence of convective terms in the turbulent energy equation on the mechanism of turbulent transport should be taken into account.

Flow-injection chemiluminescence determination of melamine in urine and plasma.

PubMed

Tang, Xiaoshuang; Shi, Xiyan; Tang, Yuhai; Yue, Zhongjin; He, Qiqi

2012-01-01

A novel flow-injection chemiluminescence method for the determination of melamine in urine and plasma was developed. It was found that melamine can remarkably enhance chemiluminescence emission from the luminol-K(3) Fe(CN)(6) system in an alkaline medium. Under the optimum conditions, chemiluminescence intensity had a good linear relationship with the concentration of melamine in the range 9.0 × 10(-9) -7.0 × 10(-6) g/mL, with a correlation coefficient of 0.9992. The detection limit (3σ) was 3.5 ng/mL. The method has been applied to determine the concentration of melamine in samples using liquid-liquid extraction. Average recoveries of melamine were 102.6% in urine samples and 95.1% in plasma samples. The method provided a reproducible and stable approach for the sensitive detection of melamine in urine and plasma samples. Copyright © 2011 John Wiley & Sons, Ltd.

Speciation of chromium (VI) and total chromium determination in welding dust samples by flow-injection analysis coupled to atomic absorption spectrometry.

PubMed

Girard, L; Hubert, J

1996-11-01

We have studied the speciation of chromium (VI) in stainless-steel welding dusts. The approach used for the analysis of Cr(VI) and total Cr relies on a flow-injection analyzer (FIA) equipped with two different sequential detectors. The system measures Cr(VI). by colorimetry (with 1,5-diphenyl carbohydrazide) and total chromium content by flame atomic absorption spectroscopy (AAS). The extraction of the samples of welding-fume dusts is achieved in a buffer solution (acetic acid and sodium acetate at pH 4). This extraction procedure gives a 96% recovery of chromium (VI). The FIA-AAS system that has been described is also more sensitive, has a lower detection limit (0.005 mug ml(-1)) and gives a better precision (< 1%) than other equivalent systems that have been previously described.

Review of Leading Approaches for Mitigating Hypersonic Vehicle Communications Blackout and a Method of Ceramic Particulate Injection Via Cathode Spot Arcs for Blackout Mitigation

NASA Technical Reports Server (NTRS)

Gillman, Eric D.; Foster, John E.; Blankson, Isaiah M.

2010-01-01

Vehicles flying at hypersonic velocities within the atmosphere become enveloped in a "plasma sheath" that prevents radio communication, telemetry, and most importantly, GPS signal reception for navigation. This radio "blackout" period has been a problem since the dawn of the manned space program and was an especially significant hindrance during the days of the Apollo missions. An appropriate mitigation method must allow for spacecraft to ground control and ground control to spacecraft communications through the reentry plasma sheath. Many mitigation techniques have been proposed, including but not limited to, aerodynamic shaping, magnetic windows, and liquid injection. The research performed on these mitigation techniques over the years will be reviewed and summarized, along with the advantages and obstacles that each technique will need to overcome to be practically implemented. A unique approach for mitigating the blackout communications problem is presented herein along with research results associated with this method. The novel method involves the injection of ceramic metal-oxide particulate into a simulated reentry plasma to quench the reentry plasma. Injection of the solid ceramic particulates is achieved by entrainment within induced, energetic cathode spot flows.

Establish an automated flow injection ESI-MS method for the screening of fragment based libraries: Application to Hsp90.

PubMed

Riccardi Sirtori, Federico; Caronni, Dannica; Colombo, Maristella; Dalvit, Claudio; Paolucci, Mauro; Regazzoni, Luca; Visco, Carlo; Fogliatto, Gianpaolo

2015-08-30

ESI-MS is a well established technique for the study of biopolymers (nucleic acids, proteins) and their non covalent adducts, due to its capacity to detect ligand-target complexes in the gas phase and allows inference of ligand-target binding in solution. In this article we used this approach to investigate the interaction of ligands to the Heat Shock Protein 90 (Hsp90). This enzyme is a molecular chaperone involved in the folding and maturation of several proteins which has been subjected in the last years to intensive drug discovery efforts due to its key role in cancer. In particular, reference compounds, with a broad range of dissociation constants from 40pM to 100μM, were tested to assess the reliability of ESI-MS for the study of protein-ligand complexes. A good agreement was found between the values measured with a fluorescence polarization displacement assay and those determined by mass spectrometry. After this validation step we describe the setup of a medium throughput screening method, based on ESI-MS, suitable to explore interactions of therapeutic relevance biopolymers with chemical libraries. Our approach is based on an automated flow injection ESI-MS method (AFI-MS) and has been applied to screen the Nerviano Medical Sciences proprietary fragment library of about 2000 fragments against Hsp90. In order to discard false positive hits and to discriminate those of them interacting with the N-terminal ATP binding site, competition experiments were performed using a reference inhibitor. Gratifyingly, this group of hits matches with the ligands previously identified by NMR FAXS techniques and confirmed by X-ray co-crystallization experiments. These results support the use of AFI-MS for the screening of medium size libraries, including libraries of small molecules with low affinity typically used in fragment based drug discovery. AFI-MS is a valid alternative to other techniques with the additional opportunities to identify compounds interacting with unpredicted or allosteric sites, without the need of any binding probes. Copyright © 2015 Elsevier B.V. All rights reserved.

Fingering and fracturing during multiphase flow in porous media (Invited)

NASA Astrophysics Data System (ADS)

Juanes, R.

2013-12-01

The displacement of one fluid by another in a porous medium give rise to a rich variety of hydrodynamic instabilities. Beyond their scientific value as fascinating models of pattern formation, unstable porous-media flows are essential to understanding many natural and man-made processes, including water infiltration in the vadose zone, carbon dioxide injection and storage in deep saline aquifers, and hydrocarbon recovery. Here, we review the pattern-selection mechanisms of a wide spectrum of porous-media flows that develop hydrodynamic instabilities, discuss their origin and the mathematical models that have been used to describe them. We point out many challenges that remain to be resolved in the context of multiphase flows, and suggest modeling approaches that may offer new quantitative understanding.

Design of a Coupled Thermoresponsive Hydrogel and Robotic System for Postinfarct Biomaterial Injection Therapy.

PubMed

Zhu, Yang; Wood, Nathan A; Fok, Kevin; Yoshizumi, Tomo; Park, Dae Woo; Jiang, Hongbin; Schwartzman, David S; Zenati, Marco A; Uchibori, Takafumi; Wagner, William R; Riviere, Cameron N

2016-09-01

In preclinical testing, ventricular wall injection of hydrogels has been shown to be effective in modulating ventricular remodeling and preserving cardiac function. For some approaches, early-stage clinical trials are under way. The hydrogel delivery method varies, with minimally invasive approaches being preferred. Endocardial injections carry a risk of hydrogel regurgitation into the circulation, and precise injection patterning is a challenge. An epicardial approach with a thermally gelling hydrogel through the subxiphoid pathway overcomes these disadvantages. A relatively stiff, thermally responsive, injectable hydrogel based on N-isopropylacrylamide and N-vinylpyrrolidone (VP gel) was synthesized and characterized. VP gel thermal behavior was tuned to couple with a transepicardial injection robot, incorporating a cooling feature to achieve injectability. Ventricular wall injections of the optimized VP gel have been performed ex vivo and on beating porcine hearts. Thermal transition temperature, viscosity, and gelling time for the VP gel were manipulated by altering N-vinylpyrrolidone content. The target parameters for cooling in the robotic system were chosen by thermal modeling to support smooth, repeated injections on an ex vivo heart. Injections at predefined locations and depth were confirmed in an infarcted porcine model. A coupled thermoresponsive hydrogel and robotic injection system incorporating a temperature-controlled injectate line was capable of targeted injections and amenable to use with a subxiphoid transepicardial approach for hydrogel injection after myocardial infarction. The confirmation of precise location and depth injections would facilitate a patient-specific planning strategy to optimize injection patterning to maximize the mechanical benefits of hydrogel placement. Copyright © 2016 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

CIRF.B Reaction-Transport-Mechanical Simulator: Applications to CO2 Injection and Reservoir Integrity Prediction

NASA Astrophysics Data System (ADS)

Park, A. J.; Tuncay, K.; Ortoleva, P. J.

2003-12-01

An important component of CO2 sequestration in geologic formations is the reactions between the injected fluid and the resident geologic material. In particular, carbonate mineral reaction rates are several orders of magnitude faster than those of siliciclastic minerals. The reactions between resident and injected components can create complex flow regime modifications, and potentially undermine the reservoir integrity by changing their mineralogic and textural compositions on engineering time scale. This process can be further enhanced due to differences in pH and temperature of the injectant from the resident sediments and fluids. CIRF.B is a multi-process simulator originally developed for basin simulations. Implemented processes include kinetic and thermodynamic reactions between minerals and fluid, fluid flow, mass-transfer, composite-media approach to sediment textural description and dynamics, elasto-visco-plastic rheology, and fracturing dynamics. To test the feasibility of applying CIRF.B to CO2 sequestration, a number of engineering scale simulations are carried out to delineate the effects of changing injectant chemistry and injection rates on both carbonate and siliciclastic sediments. Initial findings indicate that even moderate amounts of CO2 introduced into sediments can create low pH environments, which affects feldspar-clay interactions. While the amount of feldspars reacting in engineering time scale may be small, its consequence to clay alteration and permeability modfication can be significant. Results also demonstrate that diffusion-imported H+ can affect sealing properties of both siliciclastic and carbonate formations. In carbonate systems significant mass transfer can occur due to dissolution and reprecipitation. The resulting shifts in in-situ stresses can be sufficient to initiate fracturing. These simulations allow characterization of injectant fluids, thus assisting in the implementation of effective sequestration procedures.

Sensitive flow-injection spectrophotometric analysis of bromopride.

PubMed

Lima, Liliane Spazzapam; Los Weinert, Patrícia; Pezza, Leonardo; Pezza, Helena Redigolo

2014-12-10

A flow injection spectrophotometric procedure employing merging zones is proposed for direct bromopride determination in pharmaceutical formulations and biological fluids. The proposed method is based on the reaction between bromopride and p-dimethylaminocinnamaldehyde (p-DAC) in acid medium, in the presence of sodium dodecyl sulfate (SDS), resulting in formation of a violet product (λmax=565nm). Experimental design methodologies were used to optimize the experimental conditions. The Beer-Lambert law was obeyed in a bromopride concentration range of 3.63×10(-7) to 2.90×10(-5)molL(-1), with a correlation coefficient (r) of 0.9999. The limits of detection and quantification were 1.07×10(-7) and 3.57×10(-7)molL(-1), respectively. The proposed method was successfully applied to the determination of bromopride in pharmaceuticals and human urine, and recoveries of the drug from these media were in the ranges 99.6-101.2% and 98.6-102.1%, respectively. This new flow injection procedure does not require any sample pretreatment steps. Copyright © 2014 Elsevier B.V. All rights reserved.

Numerical Optimisation in Non Reacting Conditions of the Injector Geometry for a Continuous Detonation Wave Rocket Engine

NASA Astrophysics Data System (ADS)

Gaillard, T.; Davidenko, D.; Dupoirieux, F.

2015-06-01

The paper presents the methodology and the results of a numerical study, which is aimed at the investigation and optimisation of different means of fuel and oxidizer injection adapted to rocket engines operating in the rotating detonation mode. As the simulations are achieved at the local scale of a single injection element, only one periodic pattern of the whole geometry can be calculated so that the travelling detonation waves and the associated chemical reactions can not be taken into account. Here, separate injection of fuel and oxidizer is considered because premixed injection is handicapped by the risk of upstream propagation of the detonation wave. Different associations of geometrical periodicity and symmetry are investigated for the injection elements distributed over the injector head. To analyse the injection and mixing processes, a nonreacting 3D flow is simulated using the LES approach. Performance of the studied configurations is analysed using the results on instantaneous and mean flowfields as well as by comparing the mixing efficiency and the total pressure recovery evaluated for different configurations.

CFD Analyses and Jet-Noise Predictions of Chevron Nozzles with Vortex Stabilization

NASA Technical Reports Server (NTRS)

Dippold, Vance

2008-01-01

The wind computational fluid dynamics code was used to perform a series of analyses on a single-flow plug nozzle with chevrons. Air was injected from tubes tangent to the nozzle outer surface at three different points along the chevron at the nozzle exit: near the chevron notch, at the chevron mid-point, and near the chevron tip. Three injection pressures were used for each injection tube location--10, 30, and 50 psig-giving injection mass flow rates of 0.1, 0.2, and 0.3 percent of the nozzle mass flow. The results showed subtle changes in the jet plume s turbulence and vorticity structure in the region immediately downstream of the nozzle exit. Distinctive patterns in the plume structure emerged from each injection location, and these became more pronounced as the injection pressure was increased. However, no significant changes in centerline velocity decay or turbulent kinetic energy were observed in the jet plume as a result of flow injection. Furthermore, computational acoustics calculations performed with the JeNo code showed no real reduction in jet noise relative to the baseline chevron nozzle.

UV-vis Imaging of Piroxicam Supersaturation, Precipitation, and Dissolution in a Flow-Through Setup.

PubMed

Sun, Yu; Chapman, Alex; Larsen, Susan W; Jensen, Henrik; Petersen, Nickolaj J; Goodall, David M; Østergaard, Jesper

2018-06-05

Evaluation of drug precipitation is important in order to address challenges regarding low and variable bioavailability of poorly water-soluble drugs, to assess potential risk of patient safety with infusion therapy, and to explore injectable in situ suspension-forming drug delivery systems. Generally, drug precipitation is assessed in vitro through solution concentration analysis methods. Dual-wavelength UV-vis imaging is a novel imaging technique that may provide an opportunity for simultaneously monitoring changes in both solution and solid phases during precipitation. In the present study, a multimodal approach integrating UV-vis imaging, light microscopy, and Raman spectroscopy was developed for characterization of piroxicam supersaturation, precipitation, and dissolution in a flow-through setup. A solution of piroxicam dissolved in 1-methyl-2-pyrrolidinone was injected into a flowing aqueous environment (pH 7.4), causing piroxicam to precipitate. Imaging at 405 and 280 nm monitored piroxicam concentration distributions during precipitation and revealed different supersaturation levels dependent on the initial concentration of the piroxicam solution. The combination with imaging at 525 nm, light microscopy, and Raman spectroscopy measurements demonstrated concentration-dependent precipitation and the formation, growth, and dissolution of individual particles. Results emphasize the importance of the specific hydrodynamic conditions on the piroxicam precipitation. The approach used may facilitate comprehensive understanding of drug precipitation and dissolution processes and may be developed further into a basic tool for formulation screening and development.

Transport and Reactive Flow Modelling Using A Particle Tracking Method Based on Continuous Time Random Walks

NASA Astrophysics Data System (ADS)

Oliveira, R.; Bijeljic, B.; Blunt, M. J.; Colbourne, A.; Sederman, A. J.; Mantle, M. D.; Gladden, L. F.

2017-12-01

Mixing and reactive processes have a large impact on the viability of enhanced oil and gas recovery projects that involve acid stimulation and CO2 injection. To achieve a successful design of the injection schemes an accurate understanding of the interplay between pore structure, flow and reactive transport is necessary. Dependent on transport and reactive conditions, this complex coupling can also be dependent on initial rock heterogeneity across a variety of scales. To address these issues, we devise a new method to study transport and reactive flow in porous media at multiple scales. The transport model is based on an efficient Particle Tracking Method based on Continuous Time Random Walks (CTRW-PTM) on a lattice. Transport is modelled using an algorithm described in Rhodes and Blunt (2006) and Srinivasan et al. (2010); this model is expanded to enable for reactive flow predictions in subsurface rock undergoing a first-order fluid/solid chemical reaction. The reaction-induced alteration in fluid/solid interface is accommodated in the model through changes in porosity and flow field, leading to time dependent transport characteristics in the form of transit time distributions which account for rock heterogeneity change. This also enables the study of concentration profiles at the scale of interest. Firstly, we validate transport model by comparing the probability of molecular displacement (propagators) measured by Nuclear Magnetic Resonance (NMR) with our modelled predictions for concentration profiles. The experimental propagators for three different porous media of increasing complexity, a beadpack, a Bentheimer sandstone and a Portland carbonate, show a good agreement with the model. Next, we capture the time evolution of the propagators distribution in a reactive flow experiment, where hydrochloric acid is injected into a limestone rock. We analyse the time-evolving non-Fickian signatures for the transport during reactive flow and observe an increase in transport heterogeneity at latter times, representing the increase in rock heterogeneity. Evolution of transit time distribution is associated with the evolution of concentration profiles, thus highlighting the impact of initial rock structure on the reactive transport for a range of Pe and Da numbers.

Experimental Investigation of Centrifugal Compressor Stabilization Techniques

NASA Technical Reports Server (NTRS)

Skoch, Gary J.

2003-01-01

Results from a series of experiments to investigate techniques for extending the stable flow range of a centrifugal compressor are reported. The research was conducted in a high-speed centrifugal compressor at the NASA Glenn Research Center. The stabilizing effect of steadily flowing air-streams injected into the vaneless region of a vane-island diffuser through the shroud surface is described. Parametric variations of injection angle, injection flow rate, number of injectors, injector spacing, and injection versus bleed were investigated for a range of impeller speeds and tip clearances. Both the compressor discharge and an external source were used for the injection air supply. The stabilizing effect of flow obstructions created by tubes that were inserted into the diffuser vaneless space through the shroud was also investigated. Tube immersion into the vaneless space was varied in the flow obstruction experiments. Results from testing done at impeller design speed and tip clearance are presented. Surge margin improved by 1.7 points using injection air that was supplied from within the compressor. Externally supplied injection air was used to return the compressor to stable operation after being throttled into surge. The tubes, which were capped to prevent mass flux, provided 9.3 points of additional surge margin over the baseline surge margin of 11.7 points.

Flow injection chemiluminescence determination of lercanidipine based on N-chlorosuccinimide-eosin Y post-chemiluminescence reaction.

PubMed

Wang, Guowei; Zhao, Fang; Gao, Ying

2014-12-01

A novel post-chemiluminescence (PCL) reaction was discovered when lercanidipine was injected into the CL reaction mixture of N-chlorosuccinimide with alkaline eosin Y in the presence of cetyltrimethylammonium bromide (CTAB), where eosin Y was used as the CL reagent and CTAB as the surfactant. Based on this observation, a simple and highly sensitive PCL method combined with a flow injection (FI) technique was developed for the assay of lercanidipine. Under optimum conditions, the CL signal was linearly related to the concentration of lercanidipine in the range 7.0 × 10(-10) to 3.0 × 10(-6)  g/mL with a detection limit of 2.3 × 10(-10) g/mL (3σ). The relative standard deviation (RSD) was 2.1% for 1.0 × 10(-8) g/mL lercanidipine (n = 13). The proposed method had been applied to the estimation of lercanidipine in tablets and human serum samples with satisfactory results. The possible CL mechanism is also discussed briefly. Copyright © 2014 John Wiley & Sons, Ltd.

Numerical simulations of negatively buoyant jets in an immiscible fluid using the Particle Finite Element Method

NASA Astrophysics Data System (ADS)

Mier-Torrecilla, Monica; Geyer, Adelina; Phillips, Jeremy C.; Idelsohn, Sergio R.; Oñate, Eugenio

2010-05-01

In this work we investigate numerically the injection of a negatively buoyant jet into a homogenous immiscible ambient fluid using the Particle Finite Element Method (PFEM), a newly developed tool that combines the flexibility of particle-based methods with the accuracy of the finite element discretization. In order to test the applicability of PFEM to the study of negatively buoyant jets, we have compared the two-dimensional numerical results with experiments investigating the injection of a jet of dyed water through a nozzle in the base of a cylindrical tank containing rapeseed oil. In both simulations and experiments, the fountain inlet flow velocity and nozzle diameter were varied to cover a wide range of Reynolds Re and Froude numbers Fr, such that 0.1 < Fr < 30, reproducing both weak and strong fountains in a laminar regime (8 < Re < 1350). Numerical results, together with the experimental observations, allow us to describe three different fountain behaviors that have not been previously reported. Based on the Re and Fr values for the numerical and experimental simulations, we have built a regime map to define how these values may control the occurrence of each of the observed flow types. Whereas the Fr number itself provides a prediction of the maximum penetration height of the jet, its combination with the Re number provides a prediction of the flow behavior for a specific nozzle diameter and injection velocity. Conclusive remarks concerning the dynamics of negatively buoyant jets may be applied later on to several geological situations, e.g. the flow structure of a fully submerged subaqueous eruptive vent discharging magma or the replenishment of magma chambers in the Earth's crust.

Analysis of the Electrohydrodynamic Flow in a Symmetric System of Electrodes by the Method of Dynamic Current-Voltage Characteristics

NASA Astrophysics Data System (ADS)

Stishkov, Yu. K.; Zakir'yanova, R. E.

2018-04-01

We have solved the problem of injection-type through electrohydrodynamic (EHD) flow in a closed channel. We have considered a model of a liquid with four types of ions. It is shown that a through EHD flow without internal vortices in the electrode gap is formed for the ratio 2 : 1 of the initial injection current from the electrodes in the channel. The structure of the flow in different parts of the channel and the integral characteristics of the flow have been analyzed. It is shown that for a quadratic function of injection at the electrodes, the current-voltage characteristic of the flow is also quadratic.

Fuel injection assembly for gas turbine engine combustor

NASA Technical Reports Server (NTRS)

Candy, Anthony J. (Inventor); Glynn, Christopher C. (Inventor); Barrett, John E. (Inventor)

2002-01-01

A fuel injection assembly for a gas turbine engine combustor, including at least one fuel stem, a plurality of concentrically disposed tubes positioned within each fuel stem, wherein a cooling supply flow passage, a cooling return flow passage, and a tip fuel flow passage are defined thereby, and at least one fuel tip assembly connected to each fuel stem so as to be in flow communication with the flow passages, wherein an active cooling circuit for each fuel stem and fuel tip assembly is maintained by providing all active fuel through the cooling supply flow passage and the cooling return flow passage during each stage of combustor operation. The fuel flowing through the active cooling circuit is then collected so that a predetermined portion thereof is provided to the tip fuel flow passage for injection by the fuel tip assembly.

Flow Injection Analysis with Electrochemical Detection for Rapid Identification of Platinum-Based Cytostatics and Platinum Chlorides in Water

PubMed Central

Kominkova, Marketa; Heger, Zbynek; Zitka, Ondrej; Kynicky, Jindrich; Pohanka, Miroslav; Beklova, Miroslava; Adam, Vojtech; Kizek, Rene

2014-01-01

Platinum-based cytostatics, such as cisplatin, carboplatin or oxaliplatin are widely used agents in the treatment of various types of tumors. Large amounts of these drugs are excreted through the urine of patients into wastewaters in unmetabolised forms. This phenomenon leads to increased amounts of platinum ions in the water environment. The impacts of these pollutants on the water ecosystem are not sufficiently investigated as well as their content in water sources. In order to facilitate the detection of various types of platinum, we have developed a new, rapid, screening flow injection analysis method with electrochemical detection (FIA-ED). Our method, based on monitoring of the changes in electrochemical behavior of analytes, maintained by various pH buffers (Britton-Robinson and phosphate buffer) and potential changes (1,000, 1,100 and 1,200 mV) offers rapid and cheap selective determination of platinum-based cytostatics and platinum chlorides, which can also be present as contaminants in water environments. PMID:24499878

Universality Results for Multi-Layer Hele-Shaw and Porous Media Flows

NASA Astrophysics Data System (ADS)

Daripa, Prabir

2012-11-01

Saffman-Taylor instability is a well known viscosity driven instability of an interface. Motivated by a need to understand the effect of various injection policies currently in practice for chemical enhanced oil recovery, we study linear stability of displacement processes in a Hele-Shaw cell involving injection of an arbitrary number of immiscible fluid phases in succession. This is a problem involving many interfaces. Universal stability results have been obtained for this multi-layer (multi-region) flow in the sense that the results hold with arbitrary number of interfaces. These stability results have been applied to design injection policies that are considerably less unstable than the pure Saffman-Taylor case. In particular, we determine specific values of the viscosity of the fluid layers corresponding to smallest unstable band. Moreover, we discuss universal selection principle of optimal viscous profiles. The talk is based on following papers. Qatar National Fund (a member of the Qatar Foundation).

Inactivation of Bacteria in Oil Field Injected Water by a Pulsed Plasma Discharge Process

NASA Astrophysics Data System (ADS)

Xin, Qing; Li, Zhongjian; Lei, Lecheng; Yang, Bin

2016-09-01

Pulsed plasma discharge was employed to inactivate bacteria in the injection water for an oil field. The effects of water conductivity and initial concentration of bacteria on elimination efficiency were investigated in the batch and continuous flow modes. It was demonstrated that Fe2+ contained in injection water could enhance the elimination efficiency greatly. The addition of reducing agent glutathione (GSH) indicated that active radicals generated by pulsed plasma discharges played an important role in the inactivation of bacteria. Moreover, it was found that the microbial inactivation process for both batch and continuous flow mode well fitted the model based on the Weibull's survival function. supported by Zhejiang Province Welfare Technology Applied Research Project of China (No. 2014C31137), National Natural Science Foundation of China (Nos. 21436007 and U1462201), and the Fundamental Research Funds for the Central Universities of China (No. 2015QNA4032)

The influence of cavitation in the breakup of liquid free jets

NASA Astrophysics Data System (ADS)

Bode, Juergen

1991-03-01

The interaction between a diesel injection nozzle flow and the atomizing jet was investigated over a wide range of Reynolds numbers. If the pressure gradient towards the centerline of the injection nozzle, generated by the curved streamlines, becomes too large, cavitation occurs at the inlet corner. The cavitation region grows in length and boundary surface with increasing Reynolds number. The instability of the reentry flow causes unsteady fluctuations of the cavitation which influences the breakup of the liquid jet, whereby liquid films are generated which take off from the jet. Cavitation amplifies the mechanism of the atomization, based on the interaction between the jet and surrounding gas. The influence of the cavitation on the atomization is restricted to the region directly behind the nozzle exit. The injection pressure and the temperature of the gas hardly affect the atomization. The jet angle depends mainly on the density of the surrounding gas.

Superior Recess Access of the Lumbar Facet Joint.

PubMed

Demir-Deviren, Sibel; Singh, Sukhminder; Hanelin, Joshua

2017-04-01

Descriptive approach to accessing the lumbar facet joint by superior recess. This study is aimed to describe an approach to accessing the lumbar facet joint through targeting the superior recess during lumbar facet joint injections. Lumbar facet joint injections are routinely performed for both the diagnosis and treatment of chronic low back pain. Previous studies either did not specify which part of the joint to target, or recommended targeting the inferior aspect of the joint to access the inferior recess. One study did mention the superior recess as an alternative to injecting the inferior recess, but none has focused on description of the technique. This is the first time this technique has been described. The records and fluoroscopic images were reviewed for all patients over a period of 9 months (January-September 2012) using the proposed technique. This resulted in a total of 48 patients; 15 men, 29 women, and a total of 117 facet joint intra-articular injections. Among these 48 patients, injections were repeated in total of 4 cases. The average time of injections among 4 repeat cases was 121 days. The success of the procedure was confirmed with an arthrogram demonstrating contrast flowing from the superior recess inferiorly through the joint space. Successful access of the lumbar facet joint through puncture of the superior recess was seen in 114 cases, with 3 unsuccessful attempts to enter facet joints due to osteophytes at involved levels. There were no complications observed during the procedure. We find this approach to be highly successful, safe, and well tolerated by the patient and recommend it as a technique for access of the lumbar facet joint in those patients in whom direct puncture of the inferior recess is difficult.

Stabilising falling liquid film flows using feedback control

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thompson, Alice B., E-mail: alice.thompson1@imperial.ac.uk; Gomes, Susana N.; Pavliotis, Grigorios A.

2016-01-15

Falling liquid films become unstable due to inertial effects when the fluid layer is sufficiently thick or the slope sufficiently steep. This free surface flow of a single fluid layer has industrial applications including coating and heat transfer, which benefit from smooth and wavy interfaces, respectively. Here, we discuss how the dynamics of the system are altered by feedback controls based on observations of the interface height, and supplied to the system via the perpendicular injection and suction of fluid through the wall. In this study, we model the system using both Benney and weighted-residual models that account for themore » fluid injection through the wall. We find that feedback using injection and suction is a remarkably effective control mechanism: the controls can be used to drive the system towards arbitrary steady states and travelling waves, and the qualitative effects are independent of the details of the flow modelling. Furthermore, we show that the system can still be successfully controlled when the feedback is applied via a set of localised actuators and only a small number of system observations are available, and that this is possible using both static (where the controls are based on only the most recent set of observations) and dynamic (where the controls are based on an approximation of the system which evolves over time) control schemes. This study thus provides a solid theoretical foundation for future experimental realisations of the active feedback control of falling liquid films.« less

Transdiaphragmatic transport of tracer albumin from peritoneal to pleural liquid measured in rats.

PubMed

Lai-Fook, Stephen J; Houtz, Pamela K; Jones, Philip D

2005-12-01

In conscious Wistar-Kyoto rats, we studied the uptake of radioactive tracer (125)I-albumin into the pleural space and circulation after intraperitoneal (IP) injections with 1 or 5 ml of Ringer solution (3 g/dl albumin). Postmortem, we sampled pleural liquid, peritoneal liquid, and blood plasma 2-48 h after IP injection and measured their radioactivity and protein concentration. Tracer concentration was greater in pleural liquid than in plasma approximately 3 h after injection with both IP injection volumes. This behavior indicated transport of tracer through the diaphragm into the pleural space. A dynamic analysis of the tracer uptake with 5-ml IP injections showed that at least 50% of the total pleural flow was via the diaphragm. A similar estimate was derived from an analysis of total protein concentrations. Both estimates were based on restricted pleural capillary filtration and unrestricted transdiaphragmatic transport. The 5-ml IP injections did not change plasma protein concentration but increased pleural and peritoneal protein concentrations from control values by 22 and 30%, respectively. These changes were consistent with a small (approximately 8%) increase in capillary filtration and a small (approximately 20%) reduction in transdiaphragmatic flow from control values, consistent with the small (3%) decrease in hydration measured in diaphragm muscle. Thus the pleural uptake of tracer via the diaphragm with the IP injections occurred by the near-normal transport of liquid and protein.

Longitudinal flow of endolymph measured by distribution of tetraethylammonium and choline in scala media.

PubMed

Syková, E; Syka, J; Johnstone, B M; Yates, G K

1987-01-01

Longitudinal endolymph flow rate in the guinea pig cochlea was measured by determining the rate of migration of extrinsic ions, tetraethylammonium chloride (TEA) or choline, with a potassium sensitive ion-selective microelectrode (ISM). Low concentrations of iontophoretically injected TEA were detected with the ISM at various distances from the injection electrode. The results were variable when the ISM was used to record spread of TEA from turn II to turn I and vice versa. However, consistent data were obtained when the TEA spread was measured at different electrode separations (0.2, 0.5, 0.7 mm) within turn II. Electrode locations were systematically exchanged without changing their distance, i.e. the ISM electrode was placed basally or apically with respect to the TEA electrode. Comparison of data with a model, which combines the bulk diffusion of TEA and the flow of endolymph, is consistent with a rate of endolymph flow in turn II of about 0.2 mm/min, apex to base. A similar value was also obtained with the iontophoretic injection of choline. The endolymph flow rate may be different in turn I as indicated by measurements of compound action potential (CAP) changes. However, the results of experiments when TEA spread is measured at large distances must be interpreted cautiously because TEA may enter cellular walls of the cochlear duct and alternative routes of transport may be involved.

[Comparison and Discussion of National/Military Standards Related to Flow Measurement of Medical Injection Pump].

PubMed

Zhang, Nan; Zhou, Juan; Yu, Jinlai; Hua, Ziyu; Li, Yongxue; Wu, Jiangang

2018-05-30

Medical injection pump is a commonly used clinical equipment with high risk. Accurate detection of flow is an important aspect to ensure its reliable operation. In this paper, we carefully studied and analyzed the flow detection methods of three standards being used in medical injection pump detection in our country. The three standards were compared from the aspects of standard device, flow test point selection, length of test time and accuracy judgment. The advantages and disadvantages of these standards were analyzed and suggestions for improvement were put forward.

Flow visualization of film cooling with spanwise injection from a small array of holes and compound-angle injection from a large array

NASA Technical Reports Server (NTRS)

Russell, L. M.

1978-01-01

Film injection from discrete holes in a smooth, flat plate was studied for two configurations: (1) spanwise injection through a four hole staggered array; and (2) compound angle injection through a 49 hole staggered array. The ratio of boundary layer thicknesses to hole diameter and the Reynolds number were typical of gas turbine film cooling applications. Streaklines showing the motion of the injected air were obtained by photographing small, neutrally buoyant, helium-filled soap bubbles that followed the flow field.

Optimal-mass-transfer-based estimation of glymphatic transport in living brain.

PubMed

Ratner, Vadim; Zhu, Liangjia; Kolesov, Ivan; Nedergaard, Maiken; Benveniste, Helene; Tannenbaum, Allen

2015-02-21

It was recently shown that the brain-wide cerebrospinal fluid (CSF) and interstitial fluid exchange system designated the 'glymphatic pathway' plays a key role in removing waste products from the brain, similarly to the lymphatic system in other body organs 1,2 . It is therefore important to study the flow patterns of glymphatic transport through the live brain in order to better understand its functionality in normal and pathological states. Unlike blood, the CSF does not flow rapidly through a network of dedicated vessels, but rather through para-vascular channels and brain parenchyma in a slower time-domain, and thus conventional fMRI or other blood-flow sensitive MRI sequences do not provide much useful information about the desired flow patterns. We have accordingly analyzed a series of MRI images, taken at different times, of the brain of a live rat, which was injected with a paramagnetic tracer into the CSF via the lumbar intrathecal space of the spine. Our goal is twofold: (a) find glymphatic (tracer) flow directions in the live rodent brain; and (b) provide a model of a (healthy) brain that will allow the prediction of tracer concentrations given initial conditions. We model the liquid flow through the brain by the diffusion equation. We then use the Optimal Mass Transfer (OMT) approach 3 to derive the glymphatic flow vector field, and estimate the diffusion tensors by analyzing the (changes in the) flow. Simulations show that the resulting model successfully reproduces the dominant features of the experimental data.

Analysis of high gradient magnetic field effects on distribution of nanoparticles injected into pulsatile blood stream

NASA Astrophysics Data System (ADS)

Reza Habibi, Mohammad; Ghassemi, Majid; Hossien Hamedi, Mohammad

2012-04-01

Magnetic nanoparticles are widely used in a wide range of applications including data storage materials, pharmaceutical industries as magnetic separation tools, anti-cancer drug carriers and micro valve applications. The purpose of the current study is to investigate the effect of a non-uniform magnetic field on bio-fluid (blood) with magnetic nanoparticles. The effect of particles as well as mass fraction on flow field and volume concentration is investigated. The governing non-linear differential equations, concentration and Navier-stokes are coupled with the magnetic field. To solve these equations, a finite volume based code is developed and utilized. A real pulsatile velocity is utilized as inlet boundary condition. This velocity is extracted from an actual experimental data. Three percent nanoparticles volume concentration, as drug carrier, is steadily injected in an unsteady, pulsatile and non-Newtonian flow. A power law model is considered for the blood viscosity. The results show that during the systole section of the heartbeat when the blood velocity increases, the magnetic nanoparticles near the magnetic source are washed away. This is due to the sudden increase of the hydrodynamic force, which overcomes the magnetic force. The probability of vein blockage increases when the blood velocity reduces during the diastole time. As nanoparticles velocity injection decreases (longer injection time) the wall shear stress (especially near the injection area) decreases and the retention time of the magnetic nanoparticles in the blood flow increases.

Gain and temperature in a slit nozzle supersonic chemical oxygen-iodine laser with transonic and supersonic injection of iodine

NASA Astrophysics Data System (ADS)

Rosenwaks, Salman; Barmashenko, Boris D.; Bruins, Esther; Furman, Dov; Rybalkin, Victor; Katz, Arje

2002-05-01

Spatial distributions of the gain and temperament across the flow were studied for transonic and supersonic schemes of the iodine injection in a slit nozzle supersonic chemical oxygen-iodine laser as a function of the iodine and secondary nitrogen flow rate, jet penetration parameter and gas pumping rate. The mixing efficiency for supersonic injection of iodine is found to be much larger than for transonic injection, the maximum values of the gain being approximately 0.65 percent/cm for both injection schemes. Measurements of the gain distribution as a function of the iodine molar flow rate nI2 were carried out. For transonic injection the optimal value of nI2 at the flow centerline is smaller than that at the off axis location. The temperature is distributed homogeneously across the flow, increasing only in the narrow boundary layers near the walls. Opening a leak downstream of the cavity in order to decease the Mach number results in a decrease of the gain and increase of the temperature. The mixing efficiency in this case is much larger than for closed leak.

Waterflood control system for maximizing total oil recovery

DOEpatents

Patzek, Tadeusz Wiktor; Silin, Dimitriy Borisovic; De, Asoke Kumar

2005-06-07

A control system and method for determining optimal fluid injection pressure is based upon a model of a growing hydrofracture due to waterflood injection pressure. This model is used to develop a control system optimizing the injection pressure by using a prescribed injection goal coupled with the historical times, pressures, and volume of injected fluid at a single well. In this control method, the historical data is used to derive two major flow components: the transitional component, where cumulative injection volume is scaled as the square root of time, and a steady-state breakthrough component, which scales linearly with respect to time. These components provide diagnostic information and allow for the prevention of rapid fracture growth and associated massive water break through that is an important part of a successful waterflood, thereby extending the life of both injection and associated production wells in waterflood secondary oil recovery operations.

Waterflood control system for maximizing total oil recovery

DOEpatents

Patzek, Tadeusz Wiktor [Oakland, CA; Silin, Dimitriy Borisovich [Pleasant Hill, CA; De, Asoke Kumar [San Jose, CA

2007-07-24

A control system and method for determining optimal fluid injection pressure is based upon a model of a growing hydrofracture due to waterflood injection pressure. This model is used to develop a control system optimizing the injection pressure by using a prescribed injection goal coupled with the historical times, pressures, and volume of injected fluid at a single well. In this control method, the historical data is used to derive two major flow components: the transitional component, where cumulative injection volume is scaled as the square root of time, and a steady-state breakthrough component, which scales linearly with respect to time. These components provide diagnostic information and allow for the prevention of rapid fracture growth and associated massive water break through that is an important part of a successful waterflood, thereby extending the life of both injection and associated production wells in waterflood secondary oil recovery operations.

High-frequency underwater plasma discharge application in antibacterial activity

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ahmed, M. W.; Choi, S.; Lyakhov, K.

Plasma discharge is a novel disinfection and effectual inactivation approach to treat microorganisms in aqueous systems. Inactivation of Gram-negative Escherichia coli (E. coli) by generating high-frequency, high-voltage, oxygen (O{sub 2}) injected and hydrogen peroxide (H{sub 2}O{sub 2}) added discharge in water was achieved. The effect of H{sub 2}O{sub 2} dose and oxygen injection rate on electrical characteristics of discharge and E. coli disinfection has been reported. Microbial log reduction dependent on H{sub 2}O{sub 2} addition with O{sub 2} injection was observed. The time variation of the inactivation efficiency quantified by the log reduction of the initial E. coli population onmore » the basis of optical density measurement was reported. The analysis of emission spectrum recorded after discharge occurrence illustrated the formation of oxidant species (OH{sup •}, H, and O). Interestingly, the results demonstrated that O{sub 2} injected and H{sub 2}O{sub 2} added, underwater plasma discharge had fabulous impact on the E. coli sterilization. The oxygen injection notably reduced the voltage needed for generating breakdown in flowing water and escalated the power of discharge pulses. No impact of hydrogen peroxide addition on breakdown voltage was observed. A significant role of oxidant species in bacterial inactivation also has been identified. Furthermore the E. coli survivability in plasma treated water with oxygen injection and hydrogen peroxide addition drastically reduced to zero. The time course study also showed that the retardant effect on E. coli colony multiplication in plasma treated water was favorable, observed after long time. High-frequency underwater plasma discharge based biological applications is technically relevant and would act as baseline data for the development of novel antibacterial processing strategies.« less

High-frequency underwater plasma discharge application in antibacterial activity

NASA Astrophysics Data System (ADS)

Ahmed, M. W.; Choi, S.; Lyakhov, K.; Shaislamov, U.; Mongre, R. K.; Jeong, D. K.; Suresh, R.; Lee, H. J.

2017-03-01

Plasma discharge is a novel disinfection and effectual inactivation approach to treat microorganisms in aqueous systems. Inactivation of Gram-negative Escherichia coli ( E. coli) by generating high-frequency, high-voltage, oxygen (O2) injected and hydrogen peroxide (H2O2) added discharge in water was achieved. The effect of H2O2 dose and oxygen injection rate on electrical characteristics of discharge and E. coli disinfection has been reported. Microbial log reduction dependent on H2O2 addition with O2 injection was observed. The time variation of the inactivation efficiency quantified by the log reduction of the initial E. coli population on the basis of optical density measurement was reported. The analysis of emission spectrum recorded after discharge occurrence illustrated the formation of oxidant species (OH•, H, and O). Interestingly, the results demonstrated that O2 injected and H2O2 added, underwater plasma discharge had fabulous impact on the E. coli sterilization. The oxygen injection notably reduced the voltage needed for generating breakdown in flowing water and escalated the power of discharge pulses. No impact of hydrogen peroxide addition on breakdown voltage was observed. A significant role of oxidant species in bacterial inactivation also has been identified. Furthermore the E. coli survivability in plasma treated water with oxygen injection and hydrogen peroxide addition drastically reduced to zero. The time course study also showed that the retardant effect on E. coli colony multiplication in plasma treated water was favorable, observed after long time. High-frequency underwater plasma discharge based biological applications is technically relevant and would act as baseline data for the development of novel antibacterial processing strategies.

Velocity field of a round jet in a cross flow for various jet injection angles and velocity ratios. [Langley V/STOL tunnel

NASA Technical Reports Server (NTRS)

Fearn, R. L.; Weston, R. P.

1979-01-01

A subsonic round jet injected from a flat plate into a subsonic crosswind of the same temperature was investigated. Velocity and pressure measurements in planes perpendicular to the path of the jet were made for nominal jet injection angles of 45 deg, 60 deg, 75 deg, 90 deg, and 105 deg and for jet/cross flow velocity ratios of four and eight. The velocity measurements were obtained to infer the properties of the vortex pair associated with a jet in a cross flow. Jet centerline and vortex trajectories were determined and fit with an empirical equation that includes the effects of jet injection angle, jet core length, and jet/cross flow velocity ratios.

Convergence and objective functions of some fault/noise-injection-based online learning algorithms for RBF networks.

PubMed

Ho, Kevin I-J; Leung, Chi-Sing; Sum, John

2010-06-01

In the last two decades, many online fault/noise injection algorithms have been developed to attain a fault tolerant neural network. However, not much theoretical works related to their convergence and objective functions have been reported. This paper studies six common fault/noise-injection-based online learning algorithms for radial basis function (RBF) networks, namely 1) injecting additive input noise, 2) injecting additive/multiplicative weight noise, 3) injecting multiplicative node noise, 4) injecting multiweight fault (random disconnection of weights), 5) injecting multinode fault during training, and 6) weight decay with injecting multinode fault. Based on the Gladyshev theorem, we show that the convergence of these six online algorithms is almost sure. Moreover, their true objective functions being minimized are derived. For injecting additive input noise during training, the objective function is identical to that of the Tikhonov regularizer approach. For injecting additive/multiplicative weight noise during training, the objective function is the simple mean square training error. Thus, injecting additive/multiplicative weight noise during training cannot improve the fault tolerance of an RBF network. Similar to injective additive input noise, the objective functions of other fault/noise-injection-based online algorithms contain a mean square error term and a specialized regularization term.

Tuning the superstructure of ultrahigh-molecular-weight polyethylene/low-molecular-weight polyethylene blend for artificial joint application.

PubMed

Xu, Ling; Chen, Chen; Zhong, Gan-Ji; Lei, Jun; Xu, Jia-Zhuang; Hsiao, Benjamin S; Li, Zhong-Ming

2012-03-01

An easy approach was reported to achieve high mechanical properties of ultrahigh-molecular-weight polyethylene (UHMWPE)-based polyethylene (PE) blend for artificial joint application without the sacrifice of the original excellent wear and fatigue behavior of UHMWPE. The PE blend with desirable fluidity was obtained by melt mixing UHMWPE and low molecular weight polyethylene (LMWPE), and then was processed by a modified injection molding technology-oscillatory shear injection molding (OSIM). Morphological observation of the OSIM PE blend showed LMWPE contained well-defined interlocking shish-kebab self-reinforced superstructure. Addition of a small amount of long chain polyethylene (2 wt %) to LMWPE greatly induced formation of rich shish-kebabs. The ultimate tensile strength considerably increased from 27.6 MPa for conventional compression molded UHMWPE up to 78.4 MPa for OSIM PE blend along the flow direction and up to 33.5 MPa in its transverse direction. The impact strength of OSIM PE blend was increased by 46% and 7% for OSIM PE blend in the direction parallel and vertical to the shear flow, respectively. Wear and fatigue resistance were comparable to conventional compression molded UHMWPE. The superb performance of the OSIM PE blend was originated from formation of rich interlocking shish-kebab superstructure while maintaining unique properties of UHMWPE. The present results suggested the OSIM PE blend has high potential for artificial joint application. © 2012 American Chemical Society

Space shuttle booster multi-engine base flow analysis

NASA Technical Reports Server (NTRS)

Tang, H. H.; Gardiner, C. R.; Anderson, W. A.; Navickas, J.

1972-01-01

A comprehensive review of currently available techniques pertinent to several prominent aspects of the base thermal problem of the space shuttle booster is given along with a brief review of experimental results. A tractable engineering analysis, capable of predicting the power-on base pressure, base heating, and other base thermal environmental conditions, such as base gas temperature, is presented and used for an analysis of various space shuttle booster configurations. The analysis consists of a rational combination of theoretical treatments of the prominent flow interaction phenomena in the base region. These theories consider jet mixing, plume flow, axisymmetric flow effects, base injection, recirculating flow dynamics, and various modes of heat transfer. Such effects as initial boundary layer expansion at the nozzle lip, reattachment, recompression, choked vent flow, and nonisoenergetic mixing processes are included in the analysis. A unified method was developed and programmed to numerically obtain compatible solutions for the various flow field components in both flight and ground test conditions. Preliminary prediction for a 12-engine space shuttle booster base thermal environment was obtained for a typical trajectory history. Theoretical predictions were also obtained for some clustered-engine experimental conditions. Results indicate good agreement between the data and theoretical predicitons.

Nanomaterial-Based Biosensors for Detection of Pesticides and Explosives

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Jun; Lin, Yuehe

2009-01-01

In this chapter, we describe nanomaterial-based biosensors for detecting OP pesticides and explosives. CNTs and functionalized silica nanoparticles have been chosen for this study. The biosensors were combined with the flow-injection system, providing great advantages for onsite, real-time, and continuous detection of environmental pollutants such as OPs and TNT. The sensors take advantage of the electrocatalytic properties of CNTs, which makes it feasible to achieve a sensitive electrochemical detection of the products from enzymatic reactions at low potential. This approach uses a large aspect ratio of silica nanoparticles, which can be used as a carrier for loading a large amountmore » of electroactive species, such as poly(guanine), for amplified detection of explosives. These methods offer a new environmental monitoring tool for rapid, inexpensive, and highly sensitive detection of OPs or TNT compounds.« less

Transient foam flow in porous media with CAT Scanner

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, Dianbin; Brigham, W.E.

1992-03-01

Transient behavior is likely to dominate over most of the duration of a foam injection field project. Due to the lack of date, little is presently known about transient foam flow behavior. Foam flow does not follow established models such as the Buckley-Leverett theory, and no general predictive model has been derived. Therefore, both experimental data and a foam flow theory are needed. In this work, foam was injected at a constant mass rate into one-dimensional sandpacks of 1-in diameter and 24-in or 48-in length that had initially been saturate with distilled water. The system was placed in a catmore » Scanner. Data, obtained at room temperature and low pressure at various times, include both the pressure and saturation distributions. Pressure profiles showed that the pressure gradient is much greater behind the foam front than ahead of it. Moreover, the pressure gradients keep changing as the foam advances in the sandpack. This behavior differs from Buckley-Leverett theory. The CT scan results demonstrated gas channeling near the front, but eventually the foam block all these channels and sweeps the entire cross section after many pore volumes of injection. Three series of experiments were run: (1) surfactant adsorption measurements; (2) gas displacements of surfactant-laden solutions and (3) foam displacements. The first two series of experiments were made to provide the necessary parameters required to match the foam displacements. To this end, it was necessary to smooth the saturation history data, using a Langmuir-type formula. A theory was proposed based on the principles of the fractional flow curve construction method. This foam theory treats the foam as composed of infinitesimal slugs of gas of varying viscosities. The foam front has the lowest viscosity and foam at the injection end has the highest.« less

Multiplexed detection of nitrate and nitrite for capillary electrophoresis with an automated device for high injection efficiency.

PubMed

Gao, Leyi; Patterson, Eric E; Shippy, Scott A

2006-02-01

A simple automated nanoliter scale injection device which allows for reproducible 5 nL sample injections from samples with a volume of <1 microL is successfully used for conventional capillary electrophoresis (CE) and Hadamard transform (HT) CE detection. Two standard fused silica capillaries are assembled axially through the device to function as an injection and a separation capillary. Sample solution is supplied to the injection capillary using pressure controlled with a solenoid valve. Buffer solution flows gravimetrically by the junction of the injection and separation capillaries and is also gated with a solenoid valve. Plugs of sample are pushed into the space between the injection and separation capillaries for electrokinectic injection. To evaluate the performance of the injection device, several optimizations are performed including the influence of flow rates, the injected sample volume and the control of the buffer transverse flow on the overall sensitivity. The system was then applied to HT-CE-UV detection for the signal-to-noise ratio (S/N) improvement of the nitric oxide (NO) metabolites, nitrite and nitrate. In addition, signal averaging was performed to explore the possibility of greater sensitivity enhancements compared to single injections.

Flow-injection determination of trace hydrogen peroxide or glucose utilizing an amperometric biosensor based on glucose oxidase bound to a reticulated vitreous carbon electrode.

PubMed

Khayyami, M; Johansson, G; Kriz, D; Xie, B; Larsson, P O; Danielsson, B

1996-06-01

An electron transfer mediator, 8-dimethylamino-2,3-benzophenoxazine (Meldola Blue), dissolved in the carrier solution in a flow-injection system, was found to reduce the oxidation potential for hydrogen peroxide from 600-1200 mV without mediator to-100 mV vs. Ag/AgCl with the mediator present. The very low background current of reticulated vitreous carbon (RVC) at this potential makes it possible to detect very low levels of hydrogen peroxide or glucose. Glucose oxidase was covalently coupled with carbodiimide to RVC, and the RVC was formed into a column inserted in a flow-injection system. The calibration curve was linear from 30 nM to 10 microM glucose with 5 microM mediator. At higher mediator concentrations, the linear range was extended to 1000 microM, but with a much higher background current. The sample throughput was about 60 h(-1). The current response decreased to 50% of the original response after 20 days. The coulometric yield was high because the sample was pumped through the pores of the RVC. It was 16% and 55% at a flow rate of 1 ml min(-1) at mediator concentrations of 5 and 50 microM respectively.

Studies of the haemodynamic effects of creatine phosphate in man.

PubMed Central

Hurlow, R A; Aukland, A; Hardman, J; Whittington, J R

1982-01-01

1 The haemodynamic effects of intravenous creatine phosphate 1000 mg have been studied. 2 During the first 60 min following drug administration heart rate and blood pressure did not change but cardiac output fell significantly by approximately 18%. Calculated total peripheral resistance showed a corresponding significant rise, the maximum increase being approximately 24%. All these changes were beginning to diminish within 90 min after the injection. 3 Total limb blood flow measured in both arm and leg (using venous occlusion strain-gauge plethysmography) showed no appreciable changes following injection of creatine phosphate. 4 There was a progressive reduction in leg muscle blood flow (Xe133 clearance method) following injection which was statistically significant with respect to the initial level and reached a minimum (46% reduction) 50 min after the injection. 5 Skin blood flow, estimated by infra-red photoplethysmography, showed changes complementary to those seen with muscle flow. There was a progressive and significant rise to a peak (73% increase) 30 min after the injection. 6 No adverse reactions to the injections were noted. 7 Reduced cardiac output in the absence of altered total limb blood flow presumably reflects a reduction in visceral blood flow, which was not measured in this study. Within the limbs, creatine phosphate appears to result in a redistribution of blood flow from muscle to skin. Thus, these preliminary results suggest that intravenous creatine phosphate could be clinically useful in situations where short term improvement in skin blood flow would be advantageous and that further controlled studies would be justified. PMID:7093109

Preliminary Hydrogeologic Characterization Results from the Wallula Basalt Pilot Study

DOE Office of Scientific and Technical Information (OSTI.GOV)

B.P. McGrail; E. C. Sullivan; F. A. Spane

2009-12-01

The DOE's Big Sky Regional Carbon Sequestration Partnership has completed drilling the first continental flood basalt sequestration pilot borehole to a total depth (TD) of 4,110 feet on the Boise White Paper Mill property at Wallula, Washington. Site suitability was assessed prior to drilling by the 2007-2008 acquisition, processing and analysis of a four-mile, five-line three component seismic swath, which was processed as a single data-dense line. Analysis of the seismic survey data indicated a composite basalt formation thickness of {approx}8,000 feet and absence of major geologic structures (i.e., faults) along the line imaged by the seismic swath. Drilling ofmore » Wallula pilot borehole was initiated on January 13, 2009 and reached TD on April 6, 2009. Based on characterization results obtained during drilling, three basalt breccia zones were identified between the depth interval of 2,716 and 2,910 feet, as being suitable injection reservoir for a subsequent CO2 injection pilot study. The targeted injection reservoir lies stratigraphically below the massive Umtanum Member of the Grande Ronde Basalt, whose flow-interior section possesses regionally recognized low-permeability characteristics. The identified composite injection zone reservoir provides a unique and attractive opportunity to scientifically study the reservoir behavior of three inter-connected reservoir intervals below primary and secondary caprock confining zones. Drill cuttings, wireline geophysical logs, and 31one-inch diameter rotary sidewall cores provided geologic data for characterization of rock properties. XRF analyses of selected rock samples provided geochemical characterizations of the rocks and stratigraphic control for the basalt flows encountered by the Wallula pilot borehole. Based on the geochemical results, the pilot borehole was terminated in the Wapshilla Ridge 1 flow of the Grande Ronde Basalt Formation. Detailed hydrologic test characterizations of 12 basalt interflow reservoir zones and 3 flow-interior/caprock intervals were performed during drilling and immediately following reaching the final borehole drilling depth (i.e., 4,110 ft). In addition, six of the 12 basalt interflow zones were selected for detailed hydrochemical characterization. Results from the detailed hydrologic test characterization program provided the primary information on basalt interflow zone transmissivity/injectivity, and caprock permeability characteristics.« less

Reduced dose measurement of absolute myocardial blood flow using dynamic SPECT imaging in a porcine model

DOE Office of Scientific and Technical Information (OSTI.GOV)

Timmins, Rachel; Klein, Ran; Petryk, Julia

Purpose: Absolute myocardial blood flow (MBF) and myocardial flow reserve (MFR) measurements provide important additional information over traditional relative perfusion imaging. Recent advances in camera technology have made this possible with single-photon emission tomography (SPECT). Low dose protocols are desirable to reduce the patient radiation risk; however, increased noise may reduce the accuracy of MBF measurements. The authors studied the effect of reducing dose on the accuracy of dynamic SPECT MBF measurements. Methods: Nineteen 30–40 kg pigs were injected with 370 + 1110 MBq of Tc-99m sestamibi or tetrofosmin or 37 + 111 MBq of Tl-201 at rest + stress.more » Microspheres were injected simultaneously to measure MBF. The pigs were imaged in list-mode for 11 min starting at the time of injection using a Discovery NM 530c camera (GE Healthcare). Each list file was modified so that 3/4, 1/2, 1/4, 1/8, 1/16, and 1/32 of the original counts were included in the projections. Modified projections were reconstructed with CT-based attenuation correction and an energy window-based scatter correction and analyzed with FlowQuant kinetic modeling software using a 1-compartment model. A modified Renkin-Crone extraction function was used to convert the tracer uptake rate K1 to MBF values. The SPECT results were compared to those from microspheres. Results: Correlation between SPECT and microsphere MBF values for the full injected activity was r ≥ 0.75 for all 3 tracers and did not significantly degrade over all count levels. The mean MBF and MFR and the standard errors in the estimates were not significantly worse than the full-count data at 1/4-counts (Tc99m-tracers) and 1/2-counts (Tl-201). Conclusions: Dynamic SPECT measurement of MBF and MFR in pigs can be performed with 1/4 (Tc99m-tracers) or 1/2 (Tl-201) of the standard injected activity without significantly reducing accuracy and precision.« less

Stopped-in-loop flow analysis system for successive determination of trace vanadium and iron in drinking water using their catalytic reactions.

PubMed

Ayala Quezada, Alejandro; Ohara, Keisuke; Ratanawimarnwong, Nuanlaor; Nacapricha, Duangjai; Murakami, Hiroya; Teshima, Norio; Sakai, Tadao

2015-11-01

An automated stopped-in-loop flow analysis (SILFA) system is proposed for the successive catalytic determination of vanadium and iron. The determination of vanadium was based on the p-anisidine oxidation by potassium bromate in the presence of Tiron as an activator to form a reddish dye, which has an absorption maximum at 510 nm. The selectivity of the vanadium determination was greatly improved by adding diphosphate as a masking agent of iron. For the iron determination, an iron-catalyzed oxidative reaction of p-anisidine by hydrogen peroxide with 1,10-phenanthroline as an activator to produce a reddish dye (510 nm) was employed. The SILFA system consisted of two peristaltic pumps, two six-port injection valves, a four-port selection valve, a heater device, a spectrophotometric detector and a data acquisition device. One six-port injection valve was used for the isolation of a mixed solution of standard/sample and reagent to promote each catalytic reaction, and another six-port injection valve was used for switching the reagent for vanadium or iron to achieve selective determination of each analyte. The above mentioned four-port selection valve was used to select standard solutions or sample. These three valves and the two peristaltic pumps were controlled by a built-in programmable logic controller in a touchscreen controller. The obtained results showed that the proposed SILFA monitoring system constituted an effective approach for the selective determination of vanadium and iron. The limits of detection, 0.052 and 0.55 µg L(-1), were obtained for vanadium and iron, respectively. The proposed system was successfully applied to drinking water samples without any preconcentration procedures. Copyright © 2015 Elsevier B.V. All rights reserved.

Insights on Flow Behavior of Foam in Unsaturated Porous Media during Soil Flushing.

PubMed

Zhao, Yong S; Su, Yan; Lian, Jing R; Wang, He F; Li, Lu L; Qin, Chuan Y

2016-11-01

  One-dimensional column and two-dimensional tank experiments were carried out to determine (1) the physics of foam flow and propagation of foaming gas, foaming liquid, and foam; (2) the pressure distribution along foam flow and the effect of media permeability, foam flow rate and foam quality on foam injection pressure; and (3) the migration and distribution property of foam flow in homogeneous and heterogeneous sediments. The results demonstrated that: (1) gas and liquid front were formed ahead of the foam flow front, the transport speed order is foaming gas > foaming liquid > foam flowing; (2) injection pressure mainly comes from the resistance to bubble migration. Effect of media permeability on foam injection pressure mainly depends on the physics and behavior of foam flow; (3) foam has a stronger capacity of lateral spreading, besides, foam flow was uniformly distributed across the foam-occupied region, regardless of the heterogeneity of porous media.

Numerical investigation of the air injection effect on the cavitating flow in Francis hydro turbine

NASA Astrophysics Data System (ADS)

Chirkov, D. V.; Shcherbakov, P. K.; Cherny, S. G.; Skorospelov, V. A.; Turuk, P. A.

2017-09-01

At full and over load operating points, some Francis turbines experience strong self-excited pressure and power oscillations. These oscillations are occuring due to the hydrodynamic instability of the cavitating fluid flow. In many cases, the amplitude of such pulsations may be reduced substantially during the turbine operation by the air injection/ admission below the runner. Such an effect is investigated numerically in the present work. To this end, the hybrid one-three-dimensional model of the flow of the mixture "liquid-vapor" in the duct of a hydroelectric power station, which was proposed previously by the present authors, is augmented by the second gaseous component — the noncondensable air. The boundary conditions and the numerical method for solving the equations of the model are described. To check the accuracy of computing the interface "liquid-gas", the numerical method was applied at first for solving the dam break problem. The algorithm was then used for modeling the flow in a hydraulic turbine with air injection below the runner. It is shown that with increasing flow rate of the injected air, the amplitude of pressure pulsations decreases. The mechanism of the flow structure alteration in the draft tube cone has been elucidated, which leads to flow stabilization at air injection.

Reverse-Tangent Injection in a Centrifugal Compressor

NASA Technical Reports Server (NTRS)

Skoch, Gary J.

2007-01-01

Injection of working fluid into a centrifugal compressor in the reverse tangent direction has been invented as a way of preventing flow instabilities (stall and surge) or restoring stability when stall or surge has already commenced. The invention applies, in particular, to a centrifugal compressor, the diffuser of which contains vanes that divide the flow into channels oriented partly radially and partly tangentially. In reverse-tangent injection, a stream or jet of the working fluid (the fluid that is compressed) is injected into the vaneless annular region between the blades of the impeller and the vanes of the diffuser. As used here, "reverse" signifies that the injected flow opposes (and thereby reduces) the tangential component of the velocity of the impeller discharge. At the same time, the injected jet acts to increase the radial component of the velocity of the impeller discharge.

Self-sustained radial oscillating flows between parallel disks

NASA Astrophysics Data System (ADS)

Mochizuki, S.; Yang, W.-J.

1985-05-01

It is pointed out that radial flow between parallel circular disks is of interest in a number of physical systems such as hydrostatic air bearings, radial diffusers, and VTOL aircraft with centrally located downward-positioned jets. The present investigation is concerned with the problem of instability in radial flow between parallel disks. A time-dependent numerical study and experiments are conducted. Both approaches reveal the nucleation, growth, migration, and decay of annular separation bubbles (i.e. vortex or recirculation zones) in the laminar-flow region. A finite-difference technique is utilized to solve the full unsteady vorticity transport equation in the theoretical procedure, while the flow patterns in the experiments are visualized with the aid of dye-injection, hydrogen-bubble, and paraffin-mist methods. It is found that the separation and reattachment of shear layers in the radial flow through parallel disks are unsteady phenomena. The sequence of nucleation, growth, migration, and decay of the vortices is self-sustained.

Computational flow field in energy efficient engine (EEE)

NASA Astrophysics Data System (ADS)

Miki, Kenji; Moder, Jeff; Liou, Meng-Sing

2016-11-01

In this paper, preliminary results for the recently-updated Open National Combustor Code (Open NCC) as applied to the EEE are presented. The comparison between two different numerical schemes, the standard Jameson-Schmidt-Turkel (JST) scheme and the advection upstream splitting method (AUSM), is performed for the cold flow and the reacting flow calculations using the RANS. In the cold flow calculation, the AUSM scheme predicts a much stronger reverse flow in the central recirculation zone. In the reacting flow calculation, we test two cases: gaseous fuel injection and liquid spray injection. In the gaseous fuel injection case, the overall flame structures of the two schemes are similar to one another, in the sense that the flame is attached to the main nozzle, but is detached from the pilot nozzle. However, in the exit temperature profile, the AUSM scheme shows a more uniform profile than that of the JST scheme, which is close to the experimental data. In the liquid spray injection case, we expect different flame structures in this scenario. We will give a brief discussion on how two numerical schemes predict the flame structures inside the Eusing different ways to introduce the fuel injection. Supported by NASA's Transformational Tools and Technologies project.

Computational Flow Field in Energy Efficient Engine (EEE)

NASA Technical Reports Server (NTRS)

Miki, Kenji; Moder, Jeff; Liou, Meng-Sing

2016-01-01

In this paper, preliminary results for the recently-updated Open National Combustion Code (Open NCC) as applied to the EEE are presented. The comparison between two different numerical schemes, the standard Jameson-Schmidt-Turkel (JST) scheme and the advection upstream splitting method (AUSM), is performed for the cold flow and the reacting flow calculations using the RANS. In the cold flow calculation, the AUSM scheme predicts a much stronger reverse flow in the central recirculation zone. In the reacting flow calculation, we test two cases: gaseous fuel injection and liquid spray injection. In the gaseous fuel injection case, the overall flame structures of the two schemes are similar to one another, in the sense that the flame is attached to the main nozzle, but is detached from the pilot nozzle. However, in the exit temperature profile, the AUSM scheme shows a more uniform profile than that of the JST scheme, which is close to the experimental data. In the liquid spray injection case, we expect different flame structures in this scenario. We will give a brief discussion on how two numerical schemes predict the flame structures inside the EEE using different ways to introduce the fuel injection.

Online assay of bone specific alkaline phosphatase with a flow injection-bead injection system.

PubMed

Hartwell, Supaporn Kradtap; Somprayoon, Duangporn; Kongtawelert, Prachya; Ongchai, Siriwan; Arppornchayanon, Olarn; Ganranoo, Lucksagoon; Lapanantnoppakhun, Somchai; Grudpan, Kate

2007-09-26

Alkaline phosphatase (ALP) has been used as one of the biomarkers for bone resorption and liver diseases. Normally, total alkaline phosphatase is quantified along with other symptoms to determine the releasing source of the alkaline phosphatase. A semi-automated flow injection-bead injection system was proposed to conveniently and selectively assay bone alkaline phosphatase (BALP) based on its specific binding to wheat germ coated beads. Amount of BALP in serum was determined from the intensity of the yellow product produced from bound BALP on the retained beads and its substrate pNPP. The used beads were discarded and the fresh ones were introduced for the next analysis. The reaction cell was designed to be opened and closed using a computer controlled solenoid valve for a precise incubation time. The performance of the proposed system was evaluated by using it to assay BALP in human serum. The results were compared to those obtained by using a commercial ELISA kit. The system is proposed to be an easy and cost effective system for quantification of BALP as an alternative to batch wise wheat germ specific binding technique.

Supersonic Pulsed Injection

NASA Technical Reports Server (NTRS)

Cutler, A. D.; Harding, G. C.; Diskin, G. S.

2001-01-01

An injector has been developed to provide high-speed high-frequency (order 10 kHz) pulsed a supersonic crossflow. The injector nozzle is formed between the fixed internal surface of the nozzle and a freely rotating three- or four-sided wheel embedded within the device. Flow-induced rotation of the wheel causes the nozzle throat to open and close at a frequency proportional to the speed of sound of the injected gas. Measurements of frequency and mass flow rate as a function of supply pressure are discussed for various injector designs. Preliminary results are presented for wall-normal injection of helium into a Mach-2 ducted airflow. The data include schlieren images in the injectant plume in a plane normal to the flow, downstream of injection.

Film cooling effectiveness and heat transfer with injection through holes

NASA Technical Reports Server (NTRS)

Eriksen, V. L.

1971-01-01

An experimental investigation of the local film cooling effectiveness and heat transfer downstream of injection of air through discrete holes into a turbulent boundary layer of air on a flat plate is reported. Secondary air is injected through a single hole normal to the main flow and through both a single hole and a row of holes spaced at three diameter intervals with an injection angle of 35 deg to the main flow. Two values of the mainstream Reynolds number are used; the blowing rate is varied from 0.1 to 2.0. Photographs of a carbon dioxide-water fog injected into the main flow at an angle of 90 deg are also presented to show interaction between the jet and mainstream.

Flow in a discrete slotted nozzle with massive injection. [water table tests

NASA Technical Reports Server (NTRS)

Perkins, H. C.

1974-01-01

An experimental investigation has been conducted to determine the effect of massive wall injection on the flow characteristics in a slotted nozzle. Some of the experiments were performed on a water table with a slotted-nozzle test section. This has 45 deg and 15 deg half angles of convergence and divergence, respectively, throat radius of 2.5 inches, and throat width of 3 inches. The hydraulic analogy was employed to qualitatively extend the results to a compressible gas flow through the nozzle. Experimental results from the water table include contours of constant Froude and Mach number with and without injection. Photographic results are also presented for the injection through slots of CO2 and Freon-12 into a main-stream air flow in a convergent-divergent nozzle in a wind tunnel. Schlieren photographs were used to visualize the flow, and qualititative agreement between the results from the gas tunnel and water table is good.

Fine particle retention within stream storage areas at base flow and in response to a storm event

NASA Astrophysics Data System (ADS)

Drummond, J. D.; Larsen, L. G.; González-Pinzón, R.; Packman, A. I.; Harvey, J. W.

2017-07-01

Fine particles (1-100 µm), including particulate organic carbon (POC) and fine sediment, influence stream ecological functioning because they may contain or have a high affinity to sorb nitrogen and phosphorus. These particles are immobilized within stream storage areas, especially hyporheic sediments and benthic biofilms. However, fine particles are also known to remobilize under all flow conditions. This combination of downstream transport and transient retention, influenced by stream geomorphology, controls the distribution of residence times over which fine particles influence stream ecosystems. The main objective of this study was to quantify immobilization and remobilization rates of fine particles in a third-order sand-and-gravel bed stream (Difficult Run, Virginia, USA) within different geomorphic units of the stream (i.e., pool, lateral cavity, and thalweg). During our field injection experiment, a thunderstorm-driven spate allowed us to observe fine particle dynamics during both base flow and in response to increased flow. Solute and fine particles were measured within stream surface waters, pore waters, sediment cores, and biofilms on cobbles. Measurements were taken at four different subsurface locations with varying geomorphology and at multiple depths. Approximately 68% of injected fine particles were retained during base flow until the onset of the spate. Retention was evident even after the spate, with 15.4% of the fine particles deposited during base flow still retained within benthic biofilms on cobbles and 14.9% within hyporheic sediment after the spate. Thus, through the combination of short-term remobilization and long-term retention, fine particles can serve as sources of carbon and nutrients to downstream ecosystems over a range of time scales.

Fine particle retention within stream storage areas at base flow and in response to a storm event

USGS Publications Warehouse

Drummond, J. D.; Larsen, L. G.; González-Pinzón, R.; Packman, A. I.; Harvey, Judson

2017-01-01

Fine particles (1–100 µm), including particulate organic carbon (POC) and fine sediment, influence stream ecological functioning because they may contain or have a high affinity to sorb nitrogen and phosphorus. These particles are immobilized within stream storage areas, especially hyporheic sediments and benthic biofilms. However, fine particles are also known to remobilize under all flow conditions. This combination of downstream transport and transient retention, influenced by stream geomorphology, controls the distribution of residence times over which fine particles influence stream ecosystems. The main objective of this study was to quantify immobilization and remobilization rates of fine particles in a third-order sand-and-gravel bed stream (Difficult Run, Virginia, USA) within different geomorphic units of the stream (i.e., pool, lateral cavity, and thalweg). During our field injection experiment, a thunderstorm-driven spate allowed us to observe fine particle dynamics during both base flow and in response to increased flow. Solute and fine particles were measured within stream surface waters, pore waters, sediment cores, and biofilms on cobbles. Measurements were taken at four different subsurface locations with varying geomorphology and at multiple depths. Approximately 68% of injected fine particles were retained during base flow until the onset of the spate. Retention was evident even after the spate, with 15.4% of the fine particles deposited during base flow still retained within benthic biofilms on cobbles and 14.9% within hyporheic sediment after the spate. Thus, through the combination of short-term remobilization and long-term retention, fine particles can serve as sources of carbon and nutrients to downstream ecosystems over a range of time scales.

Method of injection of onabotulinumtoxinA for chronic migraine: a safe, well-tolerated, and effective treatment paradigm based on the PREEMPT clinical program.

PubMed

Blumenfeld, Andrew; Silberstein, Stephen D; Dodick, David W; Aurora, Sheena K; Turkel, Catherine C; Binder, William J

2010-10-01

Chronic migraine (CM) is a prevalent and disabling neurological disorder. Few prophylactic treatments for CM have been investigated. OnabotulinumtoxinA, which inhibits the release of nociceptive mediators, such as glutamate, substance P, and calcitonin gene-related peptide, has been evaluated in randomized, placebo-controlled studies for the preventive treatment of a variety of headache disorders, including CM. These studies have yielded insight into appropriate patient selection, injection sites, dosages, and technique. Initial approaches used a set of fixed sites for the pericranial injections. However, the treatment approach evolved to include other sites that corresponded to the location of pain and tenderness in the individual patient in addition to the fixed sites. The Phase III REsearch Evaluating Migraine Prophylaxis Therapy (PREEMPT) injection paradigm uses both fixed and follow-the-pain sites, with additional specific follow-the-pain sites considered depending on individual symptoms. The PREEMPT paradigm for injecting onabotulinumtoxinA has been shown to be safe, well-tolerated, and effective in well-designed, controlled clinical trials and is the evidence-based approach recommended to optimize clinical outcomes for patients with CM. © 2010 American Headache Society.

CO 2 Sequestration and Enhanced Oil Recovery at Depleted Oil/Gas Reservoirs

DOE PAGES

Dai, Zhenxue; Viswanathan, Hari; Xiao, Ting; ...

2017-08-18

This study presents a quantitative evaluation of the operational and technical risks of an active CO 2-EOR project. A set of risk factor metrics is defined to post-process the Monte Carlo (MC) simulations for statistical analysis. The risk factors are expressed as measurable quantities that can be used to gain insight into project risk (e.g. environmental and economic risks) without the need to generate a rigorous consequence structure, which include (a) CO 2 injection rate, (b) net CO 2 injection rate, (c) cumulative CO 2 storage, (d) cumulative water injection, (e) oil production rate, (f) cumulative oil production, (g) cumulativemore » CH 4 production, and (h) CO 2 breakthrough time. The Morrow reservoir at the Farnsworth Unit (FWU) site, Texas, is used as an example for studying the multi-scale statistical approach for CO 2 accounting and risk analysis. A set of geostatistical-based MC simulations of CO 2-oil/gas-water flow and transport in the Morrow formation are conducted for evaluating the risk metrics. A response-surface-based economic model has been derived to calculate the CO 2-EOR profitability for the FWU site with a current oil price, which suggests that approximately 31% of the 1000 realizations can be profitable. If government carbon-tax credits are available, or the oil price goes up or CO 2 capture and operating expenses reduce, more realizations would be profitable.« less

CO 2 Sequestration and Enhanced Oil Recovery at Depleted Oil/Gas Reservoirs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dai, Zhenxue; Viswanathan, Hari; Xiao, Ting

This study presents a quantitative evaluation of the operational and technical risks of an active CO 2-EOR project. A set of risk factor metrics is defined to post-process the Monte Carlo (MC) simulations for statistical analysis. The risk factors are expressed as measurable quantities that can be used to gain insight into project risk (e.g. environmental and economic risks) without the need to generate a rigorous consequence structure, which include (a) CO 2 injection rate, (b) net CO 2 injection rate, (c) cumulative CO 2 storage, (d) cumulative water injection, (e) oil production rate, (f) cumulative oil production, (g) cumulativemore » CH 4 production, and (h) CO 2 breakthrough time. The Morrow reservoir at the Farnsworth Unit (FWU) site, Texas, is used as an example for studying the multi-scale statistical approach for CO 2 accounting and risk analysis. A set of geostatistical-based MC simulations of CO 2-oil/gas-water flow and transport in the Morrow formation are conducted for evaluating the risk metrics. A response-surface-based economic model has been derived to calculate the CO 2-EOR profitability for the FWU site with a current oil price, which suggests that approximately 31% of the 1000 realizations can be profitable. If government carbon-tax credits are available, or the oil price goes up or CO 2 capture and operating expenses reduce, more realizations would be profitable.« less

Determination of Total Selenium in Infant Formulas: Comparison of the Performance of FIA and MCFA Flow Systems

PubMed Central

Pistón, Mariela; Knochen, Moisés

2012-01-01

Two flow methods, based, respectively, on flow-injection analysis (FIA) and on multicommutated flow analysis (MCFA), were compared with regard to their use for the determination of total selenium in infant formulas by hydride-generation atomic absorption spectrometry. The method based on multicommutation provided lower detection and quantification limits (0.08 and 0.27 μg L−1 compared to 0.59 and 1.95 μ L−1, resp.), higher sampling frequency (160 versus. 70 samples per hour), and reduced reagent consumption. Linearity, precision, and accuracy were similar for the two methods compared. It was concluded that, while both methods proved to be appropriate for the purpose, the MCFA-based method exhibited a better performance. PMID:22505923

Geomechanical Response of Jointed Caprock During CO2 Geological Sequestration

NASA Astrophysics Data System (ADS)

Newell, P.; Martinez, M. J.; Bishop, J. E.

2014-12-01

Geological sequestration of CO2 refers to the injection of supercritical CO2 into deep reservoirs trapped beneath a low-permeability caprock formation. Maintaining caprock integrity during the injection process is the most important factor for a successful injection. In this work we evaluate the potential for jointed caprock during injection scenarios using coupled three-dimensional multiphase flow and geomechanics modeling. Evaluation of jointed/fractured caprock systems is of particular concern to CO2 sequestration because creation or reactivation of joints (mechanical damage) can lead to enhanced pathways for leakage. In this work, we use an equivalent continuum approach to account for the joints within the caprock. Joint's aperture and non-linear stiffness of the caprock will be updated dynamically based on the effective normal stress. Effective permeability field will be updated based on the joints' aperture creating an anisotropic permeability field throughout the caprock. This feature would add another coupling between the solid and fluid in addition to basic Terzaghi's effective stress concept. In this study, we evaluate the impact of the joint's orientation and geometry of caprock and reservoir layers on geomechanical response of the CO2 geological systems. This work is supported as part of the Center for Frontiers of Subsurface Energy Security, an Energy Frontier Research Center funded by the U.S. Department of Energy, Office of Science, Office of Basic Energy Sciences under Award Number DE-SC0001114. Sandia National Laboratories is a multi-program laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the U.S. Department of Energy's National Nuclear Security Administration under contract DE-AC04-94AL85000.

Using Pressure and Volumetric Approaches to Estimate CO2 Storage Capacity in Deep Saline Aquifers

DOE PAGES

Thibeau, Sylvain; Bachu, Stefan; Birkholzer, Jens; ...

2014-12-31

Various approaches are used to evaluate the capacity of saline aquifers to store CO 2, resulting in a wide range of capacity estimates for a given aquifer. The two approaches most used are the volumetric “open aquifer” and “closed aquifer” approaches. We present four full-scale aquifer cases, where CO 2 storage capacity is evaluated both volumetrically (with “open” and/or “closed” approaches) and through flow modeling. These examples show that the “open aquifer” CO 2 storage capacity estimation can strongly exceed the cumulative CO 2 injection from the flow model, whereas the “closed aquifer” estimates are a closer approximation to themore » flow-model derived capacity. An analogy to oil recovery mechanisms is presented, where the primary oil recovery mechanism is compared to CO 2 aquifer storage without producing formation water; and the secondary oil recovery mechanism (water flooding) is compared to CO 2 aquifer storage performed simultaneously with extraction of water for pressure maintenance. This analogy supports the finding that the “closed aquifer” approach produces a better estimate of CO 2 storage without water extraction, and highlights the need for any CO 2 storage estimate to specify whether it is intended to represent CO 2 storage capacity with or without water extraction.« less

Characterization of enzymatic micromachining for construction of variable cross-section microchannel topologies

PubMed Central

Ruggles, Molly E.; Jayaraman, Arul; Ugaz, Victor M.

2016-01-01

The ability to harness enzymatic activity as an etchant to precisely machine biodegradable substrates introduces new possibilities for microfabrication. This flow-based etching is straightforward to implement, enabling patterning of microchannels with topologies that incorporate variable depth along the cross-sectional dimension. Additionally, unlike conventional small-molecule formulations, the macromolecular nature of enzymatic etchants enables features to be precisely positioned. Here, we introduce a kinetic model to characterize the enzymatic machining process and its localization by co-injection of a macromolecular inhibitor species. Our model captures the interaction between enzyme, inhibitor, and substrate under laminar flow, enabling rational prediction of etched microchannel profiles so that cross-sectional topologies incorporating complex lateral variations in depth can be constructed. We also apply this approach to achieve simultaneous widening of an entire network of microchannels produced in the biodegradable polymeric substrate poly(lactic acid), laying a foundation to construct systems incorporating a broad range of internal cross-sectional dimensions by manipulating the process conditions. PMID:27190566

Incorporating a Generic Model of Subcutaneous Insulin Absorption into the AIDA v4 Diabetes Simulator: 1. A Prospective Collaborative Development Plan

PubMed Central

Lehmann, Eldon D.; Tarín, Cristina; Bondia, Jorge; Teufel, Edgar; Deutsch, Tibor

2007-01-01

Introduction AIDA v4 is an interactive educational diabetes simulator that has been made available, for over a decade, without charge via the Internet. The software is currently freely accessible at http://www.2aida.org. This report sets out a collaborative development plan to enhance the program with a new model of subcutaneous insulin absorption, which permits the simulation of rapidly acting and very long-acting insulin analogues, as well as insulin injection doses larger than 40 units. Methods A novel, generic, physiological subcutaneous insulin absorption model is overviewed and a methodology is proposed by which this can be substituted in place of the previously adopted insulin absorption model utilized within AIDA v4.3a. Apart from this substitution it is proposed to retain the existing model of the glucoregulatory system currently used in AIDA v4.3a. Results Initial simulation results based on bench testing of this approach using MATLAB are presented for the exogenous insulin flow profile (Iex) following subcutaneous injections of a rapidly acting insulin analogue, a short-acting (regular) insulin preparation, intermediate-acting insulins (both Semilente and neutral protamine Hagedorn types), and a very long-acting insulin analogue. Discussion It is proposed to implement this collaborative development plan—first by bench testing the approach in MATLAB and then by integrating the generic subcutaneous insulin absorption Iex model into the AIDA simulator in Pascal. The aim is to provide enhanced functionality and educational simulations of regimens utilizing novel insulin analogues, as well as injections larger than 40 units of insulin. PMID:19885100

Study on cyclic injection gas override in condensate gas reservoir

NASA Astrophysics Data System (ADS)

Sun, Yan; Zhu, Weiyao; Xia, Jing; Li, Baozhu

2018-02-01

Cyclic injection gas override in condensate gas reservoirs for the large density difference between injection gas and condensate gas has been studied, but no relevant mathematical models have been built. In this paper, a mathematical model of cyclic injection gas override in condensate gas reservoir is established, considering density difference between the injected gas and the remaining condensate gas in the formation. The vertical flow ratio and override degree are used to reflect the override law of injected dry gas. Combined with the actual data of Tarim gas condensate reservoir, the parameters of injected dry gas override are calculated and analysed. The results show that the radial pressure rises or falls rapidly and the pressure gradient varies greatly in the near wells. The radial pressure varies slowly and the pressure gradient changes little in the reservoir which is within a certain distance from the wells. In the near injection well, the injected dry gas mainly migrates along the radial direction, and the vertical migration is relatively not obvious. With the distance from the injection well, the vertical flow ratio and override degree of injected dry gas increases, and the vertical flow ratio reaches the maximum in the middle of the injection well and the production well.

Subsurface storage of freshwater in South Florida; a digital model analysis of recoverability

USGS Publications Warehouse

Merritt, Michael L.

1985-01-01

As part of a study of the feasibility of recovering freshwater injected and stored underground in south Florida, a digital solute-transport model was used to investigate the relation of recovery efficiency to the variety of hydrogeologic conditions that could prevail in brackish artesian aquifers and to a variety of management alternatives. The analyses employed a modeling approach in which the control for sensitivity testing was a hypothetical aquifer considered representative of permeable zones in south Florida that might be used for storage of freshwater. Parameter variations in the tests represented possible variations in aquifer conditions in the area. The applicability of the analyses to south Florida limestone aquifers required the assumption that flow nonuniformities in those aquifers are small on the scale of volumes of water likely to be injected, and that their effect could be represented as hydrodynamic dispersion. Generally, it was shown that a loss of recovery efficiency is caused by (1) processes causing mixing of injected freshwater with native saline water (hydrodynamic dispersion), (2) processes causing the more or less irreversible displacement of the injected freshwater with respect to the well (buoyancy stratification, background hydraulic gradients, and interlayer dispersion), or (3) processes causing injection and withdrawal flow patterns to be dissimilar (directionally biased well-bore plugging, and dissimilar injection and withdrawal schedules in multiple-well systems). Other results indicated that recovery efficiency improves considerably with successive cycles, providing that each recovery phase ends when the chloride concentration of withdrawn water exceeds established criteria for potability (usually 250 milligrams per liter), and that freshwater injected into highly permeable or highly saline aquifers (such as the 'boulder zone') would buoy rapidly. Many hydrologic conditions were posed for model analysis. To have obtained comparable results with operational testing would have been more costly by orders of magnitude. The tradeoff is that the validity of results obtained from computer modeling is somewhat less certain. In particular, results must be qualified with observations that (1) the complex set of processes lumped as hydrodynamic dispersion is represented with a somewhat simplified mathematical approximation, and (2) other flow processes in limestone injection zones are as yet incompletely understood. Despite such reservations, the study is considered a practical example of the use of transport models in ground-water investigations.

Reservoir response to thermal and high-pressure well stimulation efforts at Raft River, Idaho

DOE Office of Scientific and Technical Information (OSTI.GOV)

Plummer, Mitchell; Bradford, Jacob; Moore, Joseph

An injection stimulation test begun at the Raft River geothermal reservoir in June, 2013 has produced a wealth of data describing well and reservoir response via high-resolution temperature logging and distributed temperature sensing, seismic monitoring, periodic borehole televiewer logging, periodic stepped flow rate tests and tracer injections before and after stimulation efforts. One of the primary measures of response to the stimulation is the relationship between fluid pressure and flow rate, short-term during forced flow rate changes and the long-term change in injectivity. In this paper we examine that hydraulic response using standard pumping test analysis methods, largely because pressuremore » response to the stimulation was not detected, or measurable, in other wells. Analysis of stepped rate flow tests supports the inference from other data that a large fracture, with a radial extent of one to several meters, intersects the well in the target reservoir, suggests that the flow regime is radial to a distance of only several meters and demonstrates that the pressure build-up cone reaches an effective constant head at that distance. The well’s longer term hydraulic response demonstrated continually increasing injectivity but at a dramatically faster rate later from ~2 years out and continuing to the present. The net change in injectivity is significantly greater than observed in other longterm injectivity monitoring studies, with an approximately 150–fold increase occurring over ~2.5 years. While gradually increasing injectivity is a likely consequence of slow migration of a cooling front, and consequent dilation of fractures, the steady, ongoing, rate of increase is contrary to what would be expected in a radial or linear flow regime, where the cooling front would slow with time. As a result, occasional step-like changes in injectivity, immediately following high-flow rate tests suggest that hydro shearing during high-pressure testing altered the near-well permeability structure.« less

On the existence of solutions of an equation arising in the theory of laminar flow in a uniformly porous channel with injection

NASA Technical Reports Server (NTRS)

Shih, K. G.

1986-01-01

The existence of concave solutions of Berman's equation which describes the laminar flow in channels with injection through porous walls is established. It was found that the (unique) concave solutions exist for all injection Reynolds number R < 0.

Determination of gallic acid with rhodanine by reverse flow injection analysis using simplex optimization.

PubMed

Phakthong, Wilaiwan; Liawruangrath, Boonsom; Liawruangrath, Saisunee

2014-12-01

A reversed flow injection (rFI) system was designed and constructed for gallic acid determination. Gallic acid was determined based on the formation of chromogen between gallic acid and rhodanine, resulting in a colored product with a λmax at 520 nm. The optimum conditions for determining gallic acid were also investigated. Optimizations of the experimental conditions were carried out based on the so-call univariate method. The conditions obtained were 0.6% (w/v) rhodanine, 70% (v/v) ethanol, 0.9 mol L(-1) NaOH, 2.0 mL min(-1) flow rate, 75 μL injection loop and 600 cm mixing tubing length, respectively. Comparative optimizations of the experimental conditions were also carried out by multivariate or simplex optimization method. The conditions obtained were 1.2% (w/v) rhodanine, 70% (v/v) ethanol, 1.2 mol L(-1) NaOH, flow rate 2.5 mL min(-1), 75 μL injection loop and 600 cm mixing tubing length, respectively. It was found that the optimum conditions obtained by the former optimization method were mostly similar to those obtained by the latter method. The linear relationship between peak height and the concentration of gallic acid was obtained over the range of 0.1-35.0 mg L(-1) with the detection limit 0.081 mg L(-1). The relative standard deviations were found to be in the ranges 0.46-1.96% for 1, 10, 30 mg L(-1) of gallic acid (n=11). The method has the advantages of simplicity extremely high selectivity and high precision. The proposed method was successfully applied to the determination of gallic acid in longan samples without interferent effects from other common phenolic compounds that might be present in the longan samples collected in northern Thailand. Copyright © 2014 Elsevier B.V. All rights reserved.

Fully Modulated Turbulent Diffusion Flames in Microgravity*

NASA Astrophysics Data System (ADS)

Sangras, Ravikiran; Hermanson, James C.; Johari, Hamid; Stocker, Dennis P.; Hegde, Uday G.

2001-11-01

Fully modulated, turbulent diffusion flames are studied in microgravity in 2.2 s drop-tower tests with a co-flow combustor. The fuel consists of pure ethylene or a 50/50 mixture with nitrogen; the oxidizer is either normal air or up to 40% oxygen in nitrogen. A fast solenoid valve is used to fully modulate (completely shut off) the fuel flow. The injection times range from 5 to 400 ms with a duty-cycle of 0.1 - 0.5. The fuel nozzle is 2 mm in diameter with a jet Reynolds number of 5000. The shortest injection times yield compact puffs with a mean flame length as little as 20% of that of the steady-state flame. The reduction in flame length appears to be somewhat greater in microgravity than in normal gravity. As the injection time increases, elongated flames result with a mean flame length comparable to that of a steady flame. The injection time for which the steady-state flame length is approached is shorter for lower air/fuel ratios. For a given duty-cycle, the separation between puffs is greater in microgravity than in normal gravity. For compact puffs, increasing the duty-cycle appears to increase the flame length more in microgravity than in normal gravity. The microgravity flame puffs do not exhibit the vortex-ring-like structure seen in normal gravity.

Dilution jet mixing program, phase 3

NASA Technical Reports Server (NTRS)

Srinivasan, R.; Coleman, E.; Myers, G.; White, C.

1985-01-01

The main objectives for the NASA Jet Mixing Phase 3 program were: extension of the data base on the mixing of single sided rows of jets in a confined cross flow to discrete slots, including streamlined, bluff, and angled injections; quantification of the effects of geometrical and flow parameters on penetration and mixing of multiple rows of jets into a confined flow; investigation of in-line, staggered, and dissimilar hole configurations; and development of empirical correlations for predicting temperature distributions for discrete slots and multiple rows of dilution holes.

Flame Structure and Emissions of Strongly-Pulsed Turbulent Diffusion Flames with Swirl

NASA Astrophysics Data System (ADS)

Liao, Ying-Hao

This work studies the turbulent flame structure, the reaction-zone structure and the exhaust emissions of strongly-pulsed, non-premixed flames with co-flow swirl. The fuel injection is controlled by strongly-pulsing the fuel flow by a fast-response solenoid valve such that the fuel flow is completely shut off between pulses. This control strategy allows the fuel injection to be controlled over a wide range of operating conditions, allowing the flame structure to range from isolated fully-modulated puffs to interacting puffs to steady flames. The swirl level is controlled by varying the ratio of the volumetric flow rate of the tangential air to that of the axial air. For strongly-pulsed flames, both with and without swirl, the flame geometry is strongly impacted by the injection time. Flames appear to exhibit compact, puff-like structures for short injection times, while elongated flames, similar in behaviors to steady flames, occur for long injection times. The flames with swirl are found to be shorter for the same fuel injection conditions. The separation/interaction level between flame puffs in these flames is essentially governed by the jet-off time. The separation between flame puffs decreases as swirl is imposed, consistent with the decrease in flame puff celerity due to swirl. The decreased flame length and flame puff celerity are consistent with an increased rate of air entrainment due to swirl. The highest levels of CO emissions are generally found for compact, isolated flame puffs, consistent with the rapid quenching due to rapid dilution with excess air. The imposition of swirl generally results in a decrease in CO levels, suggesting more rapid and complete fuel/air mixing by imposing swirl in the co-flow stream. The levels of NO emissions for most cases are generally below the steady-flame value. The NO levels become comparable to the steady-flame value for sufficiently short jet-off time. The swirled co-flow air can, in some cases, increase the NO emissions. The elevated NO emissions are due to a longer combustion residence time due to the flow recirculation within the swirl-induced recirculation zone. The reaction zone structure, based on OH planar laser-induced fluorescence (PLIF) is broadly consistent with the observation of luminous flame structure for these types of flames. In many cases, the reaction zone exhibits discontinuities at the instantaneous flame tip in the early period of fuel injection. These discontinuities in the reaction zone likely result from the non-ignition of injected fuel, due to a relatively slower reaction rate in comparison with the mixing rate. The discontinuity in the OH zone is generally seen to diminish with increased swirl level. Statistics generated from the OH PLIF signals show that the reaction zone area generally increases with increased swirl level, consistent with a broader and more convoluted OH-zone structure for flames with swirl. The reaction zone area for swirled flames generally exhibits a higher degree of fluctuation, suggesting a relatively stronger impact of flow turbulence on the flame structure for flames with swirl.

[Effects of carrier liquid and flow rate on the separation in gravitational field-flow fractionation].

PubMed

Guo, Shuang; Zhu, Chenqi; Gao-Yang, Yaya; Qiu, Bailing; Wu, Di; Liang, Qihui; He, Jiayuan; Han, Nanyin

2016-02-01

Gravitational field-flow fractionation is the simplest field-flow fractionation technique in terms of principle and operation. The earth' s gravity is its external field. Different sized particles are injected into a thin channel and carried by carrier fluid. The different velocities of the carrier liquid in different places results in a size-based separation. A gravitational field-flow fractionation (GrFFF) instrument was designed and constructed. Two kinds of polystyrene (PS) particles with different sizes (20 µm and 6 µm) were chosen as model particles. In this work, the separation of the sample was achieved by changing the concentration of NaN3, the percentage of mixed surfactant in the carrier liquid and the flow rate of carrier liquid. Six levels were set for each factor. The effects of these three factors on the retention ratio (R) and plate height (H) of the PS particles were investigated. It was found that R increased and H decreased with increasing particle size. On the other hand, the R and H increased with increasing flow rate. The R and H also increased with increasing NaN3 concentration. The reason was that the electrostatic repulsive force between the particles and the glass channel wall increased. The force allowed the samples approach closer to the channel wall. The results showed that the resolution and retention time can be improved by adjusting the experimental conditions. These results can provide important values to the further applications of GrFFF technique.

Parametric Studies of Flow Separation using Air Injection

NASA Technical Reports Server (NTRS)

Zhang, Wei

2004-01-01

Boundary Layer separation causes the airfoil to stall and therefore imposes dramatic performance degradation on the airfoil. In recent years, flow separation control has been one of the active research areas in the field of aerodynamics due to its promising performance improvements on the lifting device. These active flow separation control techniques include steady and unsteady air injection as well as suction on the airfoil surface etc. This paper will be focusing on the steady and unsteady air injection on the airfoil. Although wind tunnel experiments revealed that the performance improvements on the airfoil using injection techniques, the details of how the key variables such as air injection slot geometry and air injection angle etc impact the effectiveness of flow separation control via air injection has not been studied. A parametric study of both steady and unsteady air injection active flow control will be the main objective for this summer. For steady injection, the key variables include the slot geometry, orientation, spacing, air injection velocity as well as the injection angle. For unsteady injection, the injection frequency will also be investigated. Key metrics such as lift coefficient, drag coefficient, total pressure loss and total injection mass will be used to measure the effectiveness of the control technique. A design of experiments using the Box-Behnken Design is set up in order to determine how each of the variables affects each of the key metrics. Design of experiment is used so that the number of experimental runs will be at minimum and still be able to predict which variables are the key contributors to the responses. The experiments will then be conducted in the 1ft by 1ft wind tunnel according to the design of experiment settings. The data obtained from the experiments will be imported into JMP, statistical software, to generate sets of response surface equations which represent the statistical empirical model for each of the metrics as a function of the key variables. Next, the variables such as the slot geometry can be optimized using the build-in optimizer within JMP. Finally, a wind tunnel testing will be conducted using the optimized slot geometry and other key variables to verify the empirical statistical model. The long term goal for this effort is to assess the impacts of active flow control using air injection at system level as one of the task plan included in the NASAs URETI program with Georgia Institute of Technology.

Enhanced Amendment Delivery to Subsurface Using Shear Thinning Fluid and Aqueous Foam for Metal, Radionuclide, and NAPL Remediation

NASA Astrophysics Data System (ADS)

Zhong, L.; Szecsody, J.; Li, X.; Oostrom, M.; Truex, M.

2010-12-01

In many contamination sites, removal of contaminants by any active remediation efforts is not practical due to the high cost and technological limitations. Alternatively, in situ remediation is expected to be the most important remediation strategy. Delivery of reactive amendment to the contamination zone is essential for the reactions between the contaminants and remedial amendments to proceed in situ. It is a challenge to effectively deliver remedial amendment to the subsurface contamination source areas in both aquifer and vadose zone. In aquifer, heterogeneity induces fluid bypassing the low-permeability zones, resulting in certain contaminated areas inaccessible to the remedial amendment delivered by water injection, thus inhibiting the success of remedial operations. In vadose zone in situ remediation, conventional solution injection and infiltration for amendment delivery have difficulties to achieve successful lateral spreading and uniform distribution of the reactive media. These approaches also tend to displace highly mobile metal and radionuclide contaminants such as hexavalent chromium [Cr(VI)] and technetium (Tc-99), causing spreading of contaminations. Shear thinning fluid and aqueous foam can be applied to enhance the amendment delivery and improve in situ subsurface remediation efficiency under aquifer and vadose zone conditions, respectively. Column and 2-D flow cell experiments were conducted to demonstrate the enhanced delivery and improved remediation achieved by the application of shear thinning fluid and foam injection at the laboratory scale. Solutions of biopolymer xanthan gum were used as the shear thinning delivering fluids. Surfactant sodium lauryl ether sulfate (STEOL CS-330) was the foaming agent. The shear thinning fluid delivery (STFD) considerably improved the sweeping efficiency over a heterogeneous system and enhanced the non-aqueous liquid phase (NAPL) removal. The delivery of amendment into low-perm zones (LPZs) by STFD also increased the persistence of amendment solution in the LPZs after injection. Immobilization of Tc-99 was improved when a reductant was delivered by foam versus by water-based solution to contaminated vadose zone sediments. Foam delivery remarkably improved the lateral distribution of fluids compared to direct liquid injection. In heterogeneous vadose zone formation, foam injection increased the liquid flow in the high permeable zones into which very limited fluid was distributed during liquid infiltration, demonstrating improved amendment distribution uniformity in the heterogeneous system by foam delivery.

Serial office-based steroid injections for treatment of idiopathic subglottic stenosis.

PubMed

Hoffman, Matthew R; Coughlin, Adam R; Dailey, Seth H

2017-11-01

Current treatment options for idiopathic subglottic stenosis include endoscopic interventions, resection, and tracheotomy. Recently, serial office-based steroid injections were proposed as an alternative that may stabilize or induce regression of airway stenosis without the need for repeated operations. Procedure completion rate, pain, complications, effect on stenosis, time since the last operation, and limitations have not been described. Retrospective case series. Retrospective series of 19 patients undergoing serial office-based steroid injection for idiopathic subglottic stenosis. Outcome measures included completion rate, procedure-related pain scores, complications, percentage of airway stenosis, and time since the last operative intervention. Procedure completion rate was 98.8%. Average pain score during the procedure was 2.3 ± 1.7 on a 10-point scale. There were no immediate complications. One patient underwent awake tracheotomy 8 days after her second injection and was later decannulated. Average stenosis decreased from 35% ± 15% to 25% ± 15% (n = 16; P = .086) over the first of three injections and 40% ± 15% to 25% ± 10% to 20% ± 10% (n = 8; P = .002) for those patients completing two sets of three injections. Fourteen of 17 patients undergoing at least three injections have not returned to the operating room since the first injection. Office-based steroid injection represents a promising new treatment pathway for a disease that requires long-term management, offering a purely pharmacologic approach to a disorder that has traditionally been approached from a mechanical perspective. It is safe, well tolerated, and effective. Furthermore, it may help patients and physicians avoid repeated trips to the operating room and the associated risks. 4. Laryngoscope, 127:2475-2481, 2017. © 2017 The American Laryngological, Rhinological and Otological Society, Inc.

Mixing and reactions in multiphase flow through porous media

NASA Astrophysics Data System (ADS)

Jimenez-Martinez, J.; Le Borgne, T.; Meheust, Y.; Porter, M. L.; De Anna, P.; Hyman, J.; Tabuteau, H.; Turuban, R.; Carey, J. W.; Viswanathan, H. S.

2016-12-01

The understanding and quantification of flow and transport processes in multiphase systems remains a grand scientific and engineering challenge in natural and industrial systems (e.g., soils and vadose zone, CO2 sequestration, unconventional oil and gas extraction, enhanced oil recovery). Beyond the kinetic of the chemical reactions, mixing processes in porous media play a key role in controlling both fluid-fluid and fluid-solid reactions. However, conventional continuum-scale models and theories oversimplify and/or ignore many important pore-scale processes. Multiphase flows, with the creation of highly heterogeneous fluid velocity fields (i.e., low velocities regions or stagnation zones, and high velocity regions or preferential paths), makes conservative and reactive transport more complex. We present recent multi-scale experimental developments and theoretical approaches to quantify transport, mixing, and reaction and their coupling with multiphase flows. We discuss our main findings: i) the sustained concentration gradients and enhanced reactivity in a two-phase system for a continuous injection, and the comparison with a pulse line injection; ii) the enhanced mixing by a third mobile-immiscible phase; and iii) the role that capillary forces play in the localization of the fluid-solid reactions. These experimental results are for highly-idealized geometries, however, the proposed models are related to basic porous media and unsaturated flow properties, and could be tested on more complex systems.

Theory of plasma contractors for electrodynamic tethered satellite systems

NASA Technical Reports Server (NTRS)

Parks, D. E.; Katz, I.

1986-01-01

Recent data from ground and space experiments indicate that plasma releases from an object dramatically reduce the sheath impedance between the object and the ambient plasma surrounding it. Available data is in qualitative accord with the theory developed to quantify the flow of current in the sheath. Electron transport in the theory is based on a fluid model of a collisionless plasma with an effective collision frequency comparable to frequencies of plasma oscillations. The theory leads to low effective impedances varying inversely with the square root of the injected plasma density. To support such a low impedance mode of operation using an argon plasma source for example requires that only one argon ion be injected for each thirty electrons extracted from the ambient plasma. The required plasma flow rates are quite low; to extract one ampere of electron current requires a mass flow rate of about one gram of argon per day.

What controls the maximum magnitude of injection-induced earthquakes?

NASA Astrophysics Data System (ADS)

Eaton, D. W. S.

2017-12-01

Three different approaches for estimation of maximum magnitude are considered here, along with their implications for managing risk. The first approach is based on a deterministic limit for seismic moment proposed by McGarr (1976), which was originally designed for application to mining-induced seismicity. This approach has since been reformulated for earthquakes induced by fluid injection (McGarr, 2014). In essence, this method assumes that the upper limit for seismic moment release is constrained by the pressure-induced stress change. A deterministic limit is given by the product of shear modulus and the net injected fluid volume. This method is based on the assumptions that the medium is fully saturated and in a state of incipient failure. An alternative geometrical approach was proposed by Shapiro et al. (2011), who postulated that the rupture area for an induced earthquake falls entirely within the stimulated volume. This assumption reduces the maximum-magnitude problem to one of estimating the largest potential slip surface area within a given stimulated volume. Finally, van der Elst et al. (2016) proposed that the maximum observed magnitude, statistically speaking, is the expected maximum value for a finite sample drawn from an unbounded Gutenberg-Richter distribution. These three models imply different approaches for risk management. The deterministic method proposed by McGarr (2014) implies that a ceiling on the maximum magnitude can be imposed by limiting the net injected volume, whereas the approach developed by Shapiro et al. (2011) implies that the time-dependent maximum magnitude is governed by the spatial size of the microseismic event cloud. Finally, the sample-size hypothesis of Van der Elst et al. (2016) implies that the best available estimate of the maximum magnitude is based upon observed seismicity rate. The latter two approaches suggest that real-time monitoring is essential for effective management of risk. A reliable estimate of maximum plausible magnitude would clearly be beneficial for quantitative risk assessment of injection-induced seismicity.

Calculation method of water injection forward modeling and inversion process in oilfield water injection network

NASA Astrophysics Data System (ADS)

Liu, Long; Liu, Wei

2018-04-01

A forward modeling and inversion algorithm is adopted in order to determine the water injection plan in the oilfield water injection network. The main idea of the algorithm is shown as follows: firstly, the oilfield water injection network is inversely calculated. The pumping station demand flow is calculated. Then, forward modeling calculation is carried out for judging whether all water injection wells meet the requirements of injection allocation or not. If all water injection wells meet the requirements of injection allocation, calculation is stopped, otherwise the demand injection allocation flow rate of certain step size is reduced aiming at water injection wells which do not meet requirements, and next iterative operation is started. It is not necessary to list the algorithm into water injection network system algorithm, which can be realized easily. Iterative method is used, which is suitable for computer programming. Experimental result shows that the algorithm is fast and accurate.

Analysis of a Rocket Based Combined Cycle Engine during Rocket Only Operation

NASA Technical Reports Server (NTRS)

Smith, T. D.; Steffen, C. J., Jr.; Yungster, S.; Keller, D. J.

1998-01-01

The all rocket mode of operation is a critical factor in the overall performance of a rocket based combined cycle (RBCC) vehicle. However, outside of performing experiments or a full three dimensional analysis, there are no first order parametric models to estimate performance. As a result, an axisymmetric RBCC engine was used to analytically determine specific impulse efficiency values based upon both full flow and gas generator configurations. Design of experiments methodology was used to construct a test matrix and statistical regression analysis was used to build parametric models. The main parameters investigated in this study were: rocket chamber pressure, rocket exit area ratio, percent of injected secondary flow, mixer-ejector inlet area, mixer-ejector area ratio, and mixer-ejector length-to-inject diameter ratio. A perfect gas computational fluid dynamics analysis was performed to obtain values of vacuum specific impulse. Statistical regression analysis was performed based on both full flow and gas generator engine cycles. Results were also found to be dependent upon the entire cycle assumptions. The statistical regression analysis determined that there were five significant linear effects, six interactions, and one second-order effect. Two parametric models were created to provide performance assessments of an RBCC engine in the all rocket mode of operation.

A multi-channel photometric detector for multi-component analysis in flow injection analysis

PubMed Central

Tan, Aimin; Huang, Jialin; Geng, Liudi; Xu, Jinhua; Zhao, Xinna

1994-01-01

The detector, a multi-channel photometric detector, described in this paper was developed using multi-wavelength LEDs (light emitting diode) and phototransistors for absorbance measurement controlled by an Intel 8031 8-bit single chip microcomputer. Up to four flow cells can be attached to the detector. The LEDs and phototransistors are both inexpensive, and reliable. The results given by the detector for simultaneous determination of trace amounts of cobalt and cadmium in zinc sulphate electrolyte are reported. Because of the newly developed detector, this approach employs much less hardware apparatus than by employing conventional photometric detectors. PMID:18924688

A multi-channel photometric detector for multi-component analysis in flow injection analysis.

PubMed

Tan, A; Huang, J; Geng, L; Xu, J; Zhao, X

1994-01-01

The detector, a multi-channel photometric detector, described in this paper was developed using multi-wavelength LEDs (light emitting diode) and phototransistors for absorbance measurement controlled by an Intel 8031 8-bit single chip microcomputer. Up to four flow cells can be attached to the detector. The LEDs and phototransistors are both inexpensive, and reliable. The results given by the detector for simultaneous determination of trace amounts of cobalt and cadmium in zinc sulphate electrolyte are reported. Because of the newly developed detector, this approach employs much less hardware apparatus than by employing conventional photometric detectors.

Optimization of Tangential Mass Injection for Minimizing Flow Separation in a Scramjet Inlet

DTIC Science & Technology

1991-12-01

34 Aerospace EnQineering, Vol. 11. No. 8, August 1991, p.23. 26. Heppenheimer , Thomas A . Lecture notes from Hypersonic Technologies seminar. University...AFIT/GAE/ENY,/9 lD-2 ( /~ AD-A243 868 "DTIC OPTIMIZATION OF TANGENTIAL MASS INJECTION FOR MINIMIZING FLOW SEPARATION IN A SC.R-.MJET INLET THESIS...OF TANGENTIAL MASS INJECTION FOR MINIMIZING FLOW SEPARATION IN A SCRAMJET INLEr THESIS Presented to the Faculty of the School of E.ngineering of the

Pulsed Turbulent Diffusion Flames in a Coflow

NASA Astrophysics Data System (ADS)

Usowicz, James E.; Hermanson, James C.; Johari, Hamid

2000-11-01

Fully modulated diffusion flames were studied experimentally in a co-flow combustor using unheated ethylene fuel at atmospheric pressure. A fast solenoid valve was used to fully modulate (completely shut-off) the fuel flow. The fuel was released from a 2 mm diameter nozzle with injection times ranging from 2 to 750 ms. The jet exit Reynolds number was 2000 to 10,000 with a co-flow air velocity of up to 0.02 times the jet exit velocity. Establishing the effects of co-flow for the small nozzle and short injection times is required for future tests of pulsed flames under microgravity conditions. The very short injection times resulted in compact, burning puffs. The compact puffs had a mean flame length as little as 20flame for the same Reynolds number. As the injection time and fuel volume increased, elongated flames resembling starting jets resulted with a flame length comparable to that of a steady flame. For short injection times, the addition of an air co-flow resulted in an increase in flame length of nearly 50flames with longer injection times was correspondingly smaller. The effects of interaction of successive pulses on the flame length were most pronounced for the compact puffs. The emissions of unburned hydrocarbon and NOx from the pulsed flames were examined.

Disturbances to Air-Layer Skin-Friction Drag Reduction at High Reynolds Numbers

NASA Astrophysics Data System (ADS)

Dowling, David; Elbing, Brian; Makiharju, Simo; Wiggins, Andrew; Perlin, Marc; Ceccio, Steven

2009-11-01

Skin friction drag on a flat surface may be reduced by more than 80% when a layer of air separates the surface from a flowing liquid compared to when such an air layer is absent. Past large-scale experiments utilizing the US Navy's Large Cavitation Channel and a flat-plate test model 3 m wide and 12.9 m long have demonstrated air layer drag reduction (ALDR) on both smooth and rough surfaces at water flow speeds sufficient to reach downstream-distance-based Reynolds numbers exceeding 100 million. For these experiments, the incoming flow conditions, surface orientation, air injection geometry, and buoyancy forces all favored air layer formation. The results presented here extend this prior work to include the effects that vortex generators and free stream flow unsteadiness have on ALDR to assess its robustness for application to ocean-going ships. Measurements include skin friction, static pressure, airflow rate, video of the flow field downstream of the injector, and profiles of the flowing air-water mixture when the injected air forms bubbles, when it is in transition to an air layer, and when the air layer is fully formed. From these, and the prior measurements, ALDR's viability for full-scale applications is assessed.

Vitamin A determination in milk samples based on the luminol-periodate chemiluminescence system.

PubMed

Rishi, Lubna; Yaqoob, Mohammad; Waseem, Amir; Nabi, Abdul

2014-01-01

A simple and rapid flow injection (FI) method for the determination of retinyl acetate is reported based on its enhancing effect on the luminol-periodate chemiluminescence (CL) system in an alkaline medium. The detection limit (3s×blank) was 8.0×10⁻⁸ mol L⁻¹, with an injection throughput of 90 h⁻¹. The method allows linear increase of CL intensity over the retinyl acetate concentration range of 1.0-100×10⁻⁷ mol L⁻¹ (R²=0.9996) with relative standard deviations of 2.4% (n=10) for 5.0×10⁻⁷ mol L⁻¹. The key chemical and physical variables (reagent concentrations, flow rates, sample volume, and photomultiplier tube (PMT) voltage) were optimized and potential interferences were investigated. The method was successfully applied to human milk, fresh cow's milk and infant milk-based formulas and the results were in good agreement with the previously reported HPLC method. A brief discussion on the possible CL reaction mechanism is also presented.

Modeling possible spreadings of a buoyant surface plume with lagrangian and eulerian approaches at different resolutions using flow syntheses from 1992-2007 - a Gulf of Mexico study

NASA Astrophysics Data System (ADS)

Tulloch, R.; Hill, C. N.; Jahn, O.

2010-12-01

We present results from an ensemble of BP oil spill simulations. The oil spill slick is modeled as a buoyant surface plume that is transported by ocean currents modulated, in some experiments, by surface winds. Ocean currents are taken from ECCO2 project (see http://ecco2.org ) observationally constrained state estimates spanning 1992-2007. In this work we (i) explore the role of increased resolution of ocean eddies, (ii) compare inferences from particle based, lagrangian, approaches with eulerian, field based, approaches and (ii) examine the impact of differential response of oil particles and water to normal and extreme, hurricane derived, wind stress. We focus on three main questions. Is the simulated response to an oil spill markedly different for different years, depending on ocean circulation and wind forcing? Does the simulated response depend heavily on resolution and are lagrangian and eulerian estimates comparable? We start from two regional configurations of the MIT General Circulation Model (MITgcm - see http://mitgcm.org ) at 16km and 4km resolutions respectively, both covering the Gulf of Mexico and western North Atlantic regions. The simulations are driven at open boundaries with momentum and hydrographic fields from ECCO2 observationally constrained global circulation estimates. The time dependent surface flow fields from these simulations are used to transport a dye that can optionally decay over time (approximating biological breakdown) and to transport lagrangian particles. Using these experiments we examine the robustness of conclusions regarding the fate of a buoyant slick, injected at a single point. In conclusion we discuss how future drilling operations could use similar approaches to better anticipate outcomes of accidents both in this region and elsewhere.

Phase and flow behavior of mixed gas hydrate systems during gas injection

NASA Astrophysics Data System (ADS)

Darnell, K.; Flemings, P. B.; DiCarlo, D. A.

2017-12-01

We present one-dimensional, multi-phase flow model results for injections of carbon dioxide and nitrogen mixtures, or flue gas, into methane hydrate bearing reservoirs. Our flow model is coupled to a thermodynamic simulator that predicts phase stabilities as a function of composition, so multiple phases can appear, disappear, or change composition as the injection invades the reservoir. We show that the coupling of multi-phase fluid flow with phase behavior causes preferential phase fractionation in which each component flows through the system at different speeds and in different phases. We further demonstrate that phase and flow behavior within the reservoir are driven by hydrate stability of each individual component in addition to the hydrate stability of the injection composition. For example, if carbon dioxide and nitrogen are both individually hydrate stable at the reservoir P-T conditions, then any injection composition will convert all available water into hydrate and plug the reservoir. In contrast, if only carbon dioxide is hydrate stable at the reservoir P-T conditions, then nitrogen preferentially stays in the gaseous phase, while the carbon dioxide partitions into the hydrate and liquid water phases. For all injections of this type, methane originally held in hydrate is released by dissociation into the nitrogen-rich gaseous phase. The net consequence is that a gas phase composed of nitrogen and methane propagates through the reservoir in a fast-moving front. A slower-moving front lags behind where carbon dioxide and nitrogen form a mixed hydrate, but methane is absent due to dissociation-induced methane stripping from the first, fast-moving front. The entire composition path traces through the phase space as the flow develops with each front moving at different, constant velocities. This behavior is qualitatively similar to the dynamics present in enhanced oil recovery or enhanced coalbed methane recovery. These results explain why the inclusion of nitrogen in mixed gas injection into methane hydrate reservoirs has been far more successful at producing methane than pure carbon dioxide injections. These results also provide a test for the validity of equilibrium thermodynamics in transport-dominated mixed hydrate systems that can be validated by laboratory-scale flow-through experiments.

Generation of electromagnetic emission during the injection of dense supersonic plasma flows into arched magnetic field

NASA Astrophysics Data System (ADS)

Viktorov, Mikhail; Golubev, Sergey; Mansfeld, Dmitry; Vodopyanov, Alexander

2016-04-01

Interaction of dense supersonic plasma flows with an inhomogeneous arched magnetic field is one of the key problems in near-Earth and space plasma physics. It can influence on the energetic electron population formation in magnetosphere of the Earth, movement of plasma flows in magnetospheres of planets, energy release during magnetic reconnection, generation of electromagnetic radiation and particle precipitation during solar flares eruption. Laboratory study of this interaction is of big interest to determine the physical mechanisms of processes in space plasmas and their detailed investigation under reproducible conditions. In this work a new experimental approach is suggested to study interaction of supersonic (ion Mach number up to 2.7) dense (up to 1015 cm-3) plasma flows with inhomogeneous magnetic field (an arched magnetic trap with a field strength up to 3.3 T) which opens wide opportunities to model space plasma processes in laboratory conditions. Fully ionized plasma flows with density from 1013 cm-3 to 1015 cm-3 are created by plasma generator on the basis of pulsed vacuum arc discharge. Then plasma is injected in an arched open magnetic trap along or across magnetic field lines. The filling of the arched magnetic trap with dense plasma and further magnetic field lines break by dense plasma flow were experimentally demonstrated. The process of plasma deceleration during the injection of plasma flow across the magnetic field lines was experimentally demonstrated. Pulsed plasma microwave emission at the electron cyclotron frequency range was observed. It was shown that frequency spectrum of plasma emission is determined by position of deceleration region in the magnetic field of the magnetic arc, and is affected by plasma density. Frequency spectrum shifts to higher frequencies with increasing of arc current (plasma density) because the deceleration region of plasma flow moves into higher magnetic field. The observed emission can be related to the cyclotron mechanism of generation by non-equilibrium energetic electrons in dense plasma. The reported study was funded by RFBR, according to the research project No. 16-32-60056 mol_a_dk.

HyspIRI Low Latency Concept and Benchmarks

NASA Technical Reports Server (NTRS)

Mandl, Dan

2010-01-01

Topics include HyspIRI low latency data ops concept, HyspIRI data flow, ongoing efforts, experiment with Web Coverage Processing Service (WCPS) approach to injecting new algorithms into SensorWeb, low fidelity HyspIRI IPM testbed, compute cloud testbed, open cloud testbed environment, Global Lambda Integrated Facility (GLIF) and OCC collaboration with Starlight, delay tolerant network (DTN) protocol benchmarking, and EO-1 configuration for preliminary DTN prototype.

Stability of Buoyancy-Driven Gas Flow: Visualization of Coherent and Incoherent Gas Flow Patterns and Capillary Trapping

NASA Astrophysics Data System (ADS)

Geistlinger, H. W.; Samani, S.; Pohlert, M.; Jia, R.; Lazik, D.

2009-12-01

There are several mechanisms by which the CO2 can be stored: (1) In hydrodynamic trapping, the buoyant CO2 remains as a mobile fluid but is prevented from flowing back to the surface by an impermeable cap rock. (2) In solution trapping, CO2 dissolves into the brine, possibly enhanced by gravity instabilities due to the larger density of the brine-CO2 liquid mixture. (3) In mineral trapping, geochemical binding to the rock due to mineral precipitation. (4) In capillary trapping, the CO2 phase is disconnected into a coherent, mobile phase and an incoherent, immobile (trapped) phase. Recent analytical and numerical investigations [Juanes et al., 2006, 2009; Hesse et al., 2007 ] of buoyant-driven CO2-plume along a sloped aquifer are based on the following conceptual process model: (1) During the injection period, the less wetting CO2 displaces the more wetting brine in a drainage-like process. It is assumed that no capillary trapping occurs and that the CO2-network is coherent and driven both by the injection pressure and the buoyant pressure. Because of this coherence assumption a generalized Darcy-law can be used for the dynamics of the mobile, gaseous CO2-phase. (2) After injection the buoyant CO2 migrates laterally and upward, and water displaces CO2 at the trailing edge of the plume in an imbibition-like process. During this process, there are several physical mechanisms by which the water can displace the CO2 [Lenormand et al., 1983]. In addition to piston-type displacement, core-annular flow (also called: cooperative pore-body filling) may occur, i.e. the wetting phase moves along the walls and under certain conditions the CO2-core flow becomes unstable (snap-off). For water wet rocks, snap-off is the dominant mechanism [Al-Futaisi and Patzek, 2003; Valvatne and Blunt, 2004]. There seems to be consensus that the capillary trapping mechanism has a huge impact on the migration and distribution of CO2 which, in turn, affects the effectiveness of the other sequestration mechanisms. In order to investigate the stability of buoyancy-driven gas flow and the transition between coherent flow, incoherent flow, and their correlation to capillary trapping, we conducted high-resolution optical bench scale experiments. We observed a grain-size (dk) - and flow-rate (Q) dependent transition from incoherent to coherent flow. Based on core-annular flow (= cooperative pore-body filling), we propose a dynamic stability criterion that could describe our experimental results. Our experimental results for vertical gas flow support the experimental results by Lenormand et al. [1983] obtained for horizontal flow, if one takes into account that gravity leads to more unstable flow conditions. Our main results, which are in strong contradiction to the accepted conceptual model of the sloped aquifer, are: (1) Capillary Trapping can already occur during injection and at the front of the plume [Lazik et al., 2008] (2) Gas clusters or bubbles can be mobile (incoherent gas flow) and immobile (capillary trapping), and (3) Incoherent gas flow can not be described by a generalized Darcy law [Geistlinger et al., 2006, 2009].

Lumped Multi-Bubble Analysis of Injection Cooling System for Storage of Cryogenic Liquids

NASA Astrophysics Data System (ADS)

Saha, Pritam; Sandilya, Pavitra

2017-12-01

Storage of cryogenic liquids is a critical issue in many cryogenic applications. Subcooling of the liquid by bubbling a gas has been suggested to extend the storage period by reducing the boil-off loss. Liquid evaporation into the gas may cause liquid subcooling by extracting the latent heat of vaporization from the liquid. The present study aims at studying the factors affecting the liquid subcooling during gas injection. A lumped parameter model is presented to capture the effects of bubble dynamics (coalescence, breakup, deformation etc.) on the heat and mass transport between the gas and the liquid. The liquid subcooling has been estimated as a function of the key operating variables such as gas flow rate and gas injection temperature. Numerical results have been found to predict the change in the liquid temperature drop reasonably well when compared with the previously reported experimental results. This modelling approach can therefore be used in gauging the significance of various process variables on the liquid subcooling by injection cooling, as well as in designing and rating an injection cooling system.

High-Reynolds-number turbulent-boundary-layer wall pressure fluctuations with skin-friction reduction by air injection.

PubMed

Winkel, Eric S; Elbing, Brian R; Ceccio, Steven L; Perlin, Marc; Dowling, David R

2008-05-01

The hydrodynamic pressure fluctuations that occur on the solid surface beneath a turbulent boundary layer are a common source of flow noise. This paper reports multipoint surface pressure fluctuation measurements in water beneath a high-Reynolds-number turbulent boundary layer with wall injection of air to reduce skin-friction drag. The experiments were conducted in the U.S. Navy's Large Cavitation Channel on a 12.9-m-long, 3.05-m-wide hydrodynamically smooth flat plate at freestream speeds up to 20 ms and downstream-distance-based Reynolds numbers exceeding 200 x 10(6). Air was injected from one of two spanwise slots through flush-mounted porous stainless steel frits (approximately 40 microm mean pore diameter) at volume flow rates from 17.8 to 142.5 l/s per meter span. The two injectors were located 1.32 and 9.78 m from the model's leading edge and spanned the center 87% of the test model. Surface pressure measurements were made with 16 flush-mounted transducers in an "L-shaped" array located 10.7 m from the plate's leading edge. When compared to no-injection conditions, the observed wall-pressure variance was reduced by as much as 87% with air injection. In addition, air injection altered the inferred convection speed of pressure fluctuation sources and the streamwise coherence of pressure fluctuations.

CFD modeling of catheter-based Chemofilter device for filtering chemotherapy drugs from venous flow

NASA Astrophysics Data System (ADS)

Maani, Nazanin; Yee, Daryl; Nosonovsky, Michael; Greer, Julia; Hetts, Steven; Rayz, Vitaliy

2017-11-01

Purpose: Intra-arterial chemotherapy, a procedure where drugs are injected into arteries supplying a tumor, may cause systemic toxicity. The Chemofilter device, deployed in a vein downstream of the tumor, can chemically filter the excessive drugs from the circulation. In our study, CFD modeling of blood flow through the Chemofilter is used to optimize its hemodynamic performance. Methods:The Chemofilter consists of a porous membrane attached to a stent-like frame of the RX Accunet distal protection filters used for capturing blood clots. The membrane is formed by a lattice of symmetric micro-cells. This design provides a large surface area for the drug binding, and allows blood cells to pass through the lattice. A two-scale modeling approach is used, where the flow through individual micro-cells is simulated to determine the lattice permeability and then the entire device is modeled as a porous membrane. Results: The simulations detected regions of flow stagnation and recirculation caused by the membrane and its supporting frame. The effect of the membrane's leading angle on the velocity and pressure fields was determined. The device optimization will help the efficacy of drug absorption, while the risk of blood clotting reduces. NIH NCI R01CA194533.

Critical Dynamics of Gravito-Convective Mixing in Geological Carbon Sequestration

PubMed Central

Soltanian, Mohamad Reza; Amooie, Mohammad Amin; Dai, Zhenxue; Cole, David; Moortgat, Joachim

2016-01-01

When CO2 is injected in saline aquifers, dissolution causes a local increase in brine density that can cause Rayleigh-Taylor-type gravitational instabilities. Depending on the Rayleigh number, density-driven flow may mix dissolved CO2 throughout the aquifer at fast advective time-scales through convective mixing. Heterogeneity can impact density-driven flow to different degrees. Zones with low effective vertical permeability may suppress fingering and reduce vertical spreading, while potentially increasing transverse mixing. In more complex heterogeneity, arising from the spatial organization of sedimentary facies, finger propagation is reduced in low permeability facies, but may be enhanced through more permeable facies. The connectivity of facies is critical in determining the large-scale transport of CO2-rich brine. We perform high-resolution finite element simulations of advection-diffusion transport of CO2 with a focus on facies-based bimodal heterogeneity. Permeability fields are generated by a Markov Chain approach, which represent facies architecture by commonly observed characteristics such as volume fractions. CO2 dissolution and phase behavior are modeled with the cubic-plus-association equation-of-state. Our results show that the organization of high-permeability facies and their connectivity control the dynamics of gravitationally unstable flow. We discover new flow regimes in both homogeneous and heterogeneous media and present quantitative scaling relations for their temporal evolution. PMID:27808178

Determination of available phosphorus in soils by using a new extraction procedure and a flow injection amperometric system.

PubMed

Jakmunee, Jaroon; Junsomboon, Jaroon

2009-09-15

A new extraction procedure based on an off-line extraction column was proposed for extracting of available phosphorus from soils. The column was fabricated from a plastic syringe fitted at the bottom with a cotton wool and a piece of filter paper to support a soil sample. An aliquot (50 mL) of extracting solution (0.05 M HCl+0.0125 M H(2)SO(4)) was used to extract the sample under gravity flow and the eluate was collected in a polyethylene bottle. The extract was then analyzed for phosphorus contents by a simple flow injection amperometric system, employing a set of three-way solenoid valves as an injection valve. The method is based on the electrochemical reduction of 12-molybdophosphate which is produced on-line by the reaction of orthophosphate with acidic molybdate and the electrical current produced was directly proportional to the concentration of phosphate in range of 0.1-10.0 mg L(-1) PO(4)-P, with a detection limit of 0.02 mg L(-1). Relative standard for 11 replicate injections of 5 mg L(-1) PO(4)-P was 0.5%. A sample through put of 35 h(-1) was achieved, with consumption of 14 mg KCl, 10mg ammonium molybdate and 0.05 mL H(2)SO(4) per analysis. The detection system does not suffer from the interferences that are encountered in the photometric method such as colored substances, colloids, metal ions, silicate and refractive index effect (Schlieren effect). The results obtained by the column extraction procedure were well correlated with those obtained by the steady-state extraction procedure, but showed slightly higher extraction efficiency.

Liquid sprays and flow studies in the direct-injection diesel engine under motored conditions

NASA Technical Reports Server (NTRS)

Nguyen, Hung Lee; Carpenter, Mark H.; Ramos, Juan I.; Schock, Harold J.; Stegeman, James D.

1988-01-01

A two dimensional, implicit finite difference method of the control volume variety, a two equation model of turbulence, and a discrete droplet model were used to study the flow field, turbulence levels, fuel penetration, vaporization, and mixing in diesel engine environments. The model was also used to study the effects of engine speed, injection angle, spray cone angle, droplet distribution, and intake swirl angle on the flow field, spray penetration and vaporization, and turbulence in motored two-stroke diesel engines. It is shown that there are optimum conditions for injection, which depend on droplet distribution, swirl, spray cone angle, and injection angle. The optimum conditions result in good spray penetration and vaporization and in good fuel mixing. The calculation presented clearly indicates that internal combustion engine models can be used to assess, at least qualitatively, the effects of injection characteristics and engine operating conditions on the flow field and on the spray penetration and vaporization in diesel engines.

Sample injection and electrophoretic separation on a simple laminated paper based analytical device.

PubMed

Xu, Chunxiu; Zhong, Minghua; Cai, Longfei; Zheng, Qingyu; Zhang, Xiaojun

2016-02-01

We described a strategy to perform multistep operations on a simple laminated paper-based separation device by using electrokinetic flow to manipulate the fluids. A laminated crossed-channel paper-based separation device was fabricated by cutting a filter paper sheet followed by lamination. Multiple function units including sample loading, sample injection, and electrophoretic separation were integrated on a single paper based analytical device for the first time, by applying potential at different reservoirs for sample, sample waste, buffer, and buffer waste. As a proof-of-concept demonstration, mixed sample solution containing carmine and sunset yellow were loaded in the sampling channel, and then injected into separation channel followed by electrophoretic separation, by adjusting the potentials applied at the four terminals of sampling and separation channel. The effects of buffer pH, buffer concentration, channel width, and separation time on resolution of electrophoretic separation were studied. This strategy may be used to perform multistep operations such as reagent dilution, sample injection, mixing, reaction, and separation on a single microfluidic paper based analytical device, which is very attractive for building micro total analysis systems on microfluidic paper based analytical devices. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Numerical simulations of an impinging liquid spray in a cross-flow

NASA Astrophysics Data System (ADS)

Gomatam, Sreekar; Vengadesan, S.; Chakravarthy, S. R.

2017-11-01

The characteristics of a liquid spray in a uniform cross-flow field are numerically simulated in this study. A hollow cone liquid spray is injected perpendicular to the air stream flowing through a rectangular duct under room temperature and pressure. An Eulerian-Lagrangian framework is adopted to simulate the spray in cross-flow phenomenon. The cross-flow velocity is varied from 6-12 m/s while the liquid injection pressure is varied from 0.3-0.6 MPa. The liquid droplets from the injected spray undergo breakup and/or coalescence further in the cross-flow. Moreover, the spray injected into the cross-flow impinges on the opposite wall resulting in the formation of a liquid film. This liquid film disintegrates further into discrete droplets because of the impingement of the droplets from the spray and the shear from the cross-flow. The overall distribution of the droplets in the cross-flow for varying conditions is studied in detail. The evolution of the liquid film with space and time for varying conditions is also investigated. Suitable sub-models are used to numerically model the droplet break-up, coalescence, liquid film formation and disintegration, splashing of the droplets on the film and subsequent formation of daughter droplets. Department of Applied Mechanics, Indian Inst of Tech-Madras.

A new Doppler-echo method to quantify regurgitant volume.

PubMed

Wang, S S; Rubenstein, J J; Goldman, M; Sidd, J J

1992-01-01

An in vitro technique using color flow imaging and continuous wave Doppler was developed to measure the initial regurgitant flow jet diameter and velocity integral to yield the parameters for a volume calculation. Jets were produced by volume-controlled injection through tubes of various diameters (1.3, 1.9, 2.8, and 3.5 mm) to deliver volumes from 1 to 7 ml over 100 to 300 msec at pressures from 40 to 200 mm Hg. One hundred forty-five samples were obtained. Flow jet diameter consistently overestimated tube diameter by 2 mm when injected volume was 1.5 to 7 ml and by 1.5 mm when injected volume was less than 1.5 ml. This offset was stable with various transducers (2.5, 3.5, 5.0 MHz) at normal gain setting (just under noise). Therefore, corrected flow jet diameter (FJD) = FJD - 2 mm, and Doppler volume = corrected flow jet area x velocity integral. A range of injectates from 1.1 to 7 ml generated Doppler volume of 1.0 to 8.2 ml. The relation between Doppler volume (DV) and injected volume (IV) was DV = 1.079 IV - 0.22, r2 = 0.945, p less than 0.01. This relation was not altered by tube diameter. Thus a method combining color flow imaging and continuous wave Doppler provides a reliable and accurate measure of in vitro flow volume.

Polyion selective polymeric membrane-based pulstrode as a detector in flow-injection analysis.

PubMed

Bell-Vlasov, Andrea K; Zajda, Joanna; Eldourghamy, Ayman; Malinowska, Elzbieta; Meyerhoff, Mark E

2014-04-15

A method for the detection of polyions using fully reversible polyion selective polymeric membrane type pulstrodes as detectors in a flow-injection analysis (FIA) system is examined. The detection electrode consists of a plasticized polymeric membrane doped with 10 wt % of tridodecylmethylammonium-dinonylnaphthalene sulfonate (TDMA/DNNS) ion-exchanger salt. The pulse sequence used involves a short (1 s) galvanostatic pulse, an open-circuit pulse (0.5 s) during which the EMF of the cell is measured, and a longer (15 s) potentiostatic pulse to return the membrane to its original chemical composition. It is shown that total pulse sequence times can be optimized to yield reproducible real-time detection of injected samples of protamine and heparin at up to 20 samples/h. Further, it is shown that the same membrane detector can be employed for FIA detection of both polycations at levels ≥10 μg/mL and polyanions at levels of ≥40 μg/mL by changing the direction of the galvanostatic pulse. The methodology described may also be applicable in the detection of polyionic species at low levels in other flowing configurations, such as in liquid chromatography and capillary electrophoresis.

Flow injection gas chromatography with sulfur chemiluminescence detection for the analysis of total sulfur in complex hydrocarbon matrixes.

PubMed

Hua, Yujuan; Hawryluk, Myron; Gras, Ronda; Shearer, Randall; Luong, Jim

2018-01-01

A fast and reliable analytical technique for the determination of total sulfur levels in complex hydrocarbon matrices is introduced. The method employed flow injection technique using a gas chromatograph as a sample introduction device and a gas phase dual-plasma sulfur chemiluminescence detector for sulfur quantification. Using the technique described, total sulfur measurement in challenging hydrocarbon matrices can be achieved in less than 10 s with sample-to-sample time <2 min. The high degree of selectivity and sensitivity toward sulfur compounds of the detector offers the ability to measure low sulfur levels with a detection limit in the range of 20 ppb w/w S. The equimolar response characteristic of the detector allows the quantitation of unknown sulfur compounds and simplifies the calibration process. Response is linear over a concentration range of five orders of magnitude, with a high degree of repeatability. The detector's lack of response to hydrocarbons enables direct analysis without the need for time-consuming sample preparation and chromatographic separation processes. This flow injection-based sulfur chemiluminescence detection technique is ideal for fast analysis or trace sulfur analysis. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

A simple and sensitive flow injection method based on the catalytic activity of CdS quantum dots in an acidic permanganate chemiluminescence system for determination of formaldehyde in water and wastewater.

PubMed

Khataee, Alireza; Lotfi, Roya; Hasanzadeh, Aliyeh; Iranifam, Mortaza

2016-04-01

A simple and sensitive flow injection chemiluminescence (CL) method in which CdS quantum dots (QDs) enhanced the CL intensity of a KMnO4-formaldehyde (HCHO) reaction was offered for the determination of HCHO. This CL system was based on the catalytic activity of CdS QDs and their participation in the CL resonance energy transfer (CRET) phenomenon. A possible mechanism for the supplied CL system was proposed using the kinetic curves of the CL systems and the spectra of CL, photoluminescence (PL) and ultraviolet-visible (UV-Vis). The emanated CL intensity of the KMnO4-CdS QDs system was amplified in the presence of a trace level of HCHO. Based on this enhancement effect, a simple and sensitive flow injection CL method was suggested for the determination of HCHO concentration in environmental water and wastewater samples. Under selected optimized experimental conditions, the increased CL intensity was proportional to the HCHO concentration in the range of 0.03-4.5 μg L(-1) and 4.5-10.0 μg L(-1). The detection limits (3σ) were 0.0003 μg L(-1) and 1.2 μg L(-1). The relative standard deviations (RSD%) for eleven replicate determinations of 4.0 μg L(-1) HCHO were 2.2%. Furthermore, the feasibility of the developed method was investigated via the determination of HCHO concentration in environmental water and wastewater samples.

Convective transport resistance in the vitreous humor

NASA Astrophysics Data System (ADS)

Penkova, Anita; Sadhal, Satwindar; Ratanakijsuntorn, Komsan; Moats, Rex; Tang, Yang; Hughes, Patrick; Robinson, Michael; Lee, Susan

2012-11-01

It has been established by MRI visualization experiments that the convection of nanoparticles and large molecules with high rate of water flow in the vitreous humor will experience resistance, depending on the respective permeabilities of the injected solute. A set of experiments conducted with Gd-DTPA (Magnevist, Bayer AG, Leverkusen, Germany) and 30 nm gadolinium-based particles (Gado CELLTrackTM, Biopal, Worcester, MA) as MRI contrast agents showed that the degree of convective transport in this Darcy-type porous medium varies between the two solutes. These experiments consisted of injecting a mixture of the two (a 30 μl solution of 2% Magnevist and 1% nanoparticles) at the middle of the vitreous of an ex vivo whole bovine eye and subjecting the vitreous to water flow rate of 100 μl/min. The water (0.9% saline solution) was injected at the top of the eye, and was allowed to drain through small slits cut at the bottom of the eyeball. After 50 minutes of pumping, MRI images showed that the water flow carried the Gd-DTPA farther than the nanoparticles, even though the two solutes, being mixed, were subjected to the same convective flow conditions. We find that the convected solute lags the water flow, depending on the solute permeability. The usual convection term needs to be adjusted to allow for the filtration effect on the larger particles in the form (1- σ) u . ∇ c with important implications for the modeling of such systems.

Radial solute transport in highly heterogeneous aquifers: Modeling and experimental comparison

NASA Astrophysics Data System (ADS)

Di Dato, Mariaines; Fiori, Aldo; de Barros, Felipe P. J.; Bellin, Alberto

2017-07-01

We analyze solute transport in a radially converging 3-D flow field in a porous medium with spatially heterogeneous hydraulic conductivity (K). The aim of the paper is to analyze the impact of heterogeneity and the mode of injection on BreakThrough Curves (BTCs) detected at a well pumping a contaminated aquifer. The aquifer is conceptualized as an ensemble of blocks of uniform but contrasting K and the analysis makes use of the travel time approach. Despite the approximations introduced, the model reproduces a laboratory experiment without calibration of transport parameters. Our results also show excellent agreement with numerical simulations for different levels of heterogeneity. We focus on the impact on the BTC of both heterogeneity in K and solute release conditions. It is shown that the injection mode matters, and the differences in the BTCs between uniform and flux-proportional injection increase with the heterogeneity of the K-field. Furthermore, we study the effect of heterogeneity and mode of injection on early and late arrivals at the well.

Caprock Integrity during Hydrocarbon Production and CO2 Injection in the Goldeneye Reservoir

NASA Astrophysics Data System (ADS)

Salimzadeh, Saeed; Paluszny, Adriana; Zimmerman, Robert

2016-04-01

Carbon Capture and Storage (CCS) is a key technology for addressing climate change and maintaining security of energy supplies, while potentially offering important economic benefits. UK offshore, depleted hydrocarbon reservoirs have the potential capacity to store significant quantities of carbon dioxide, produced during power generation from fossil fuels. The Goldeneye depleted gas condensate field, located offshore in the UK North Sea at a depth of ~ 2600 m, is a candidate for the storage of at least 10 million tons of CO2. In this research, a fully coupled, full-scale model (50×20×8 km), based on the Goldeneye reservoir, is built and used for hydro-carbon production and CO2 injection simulations. The model accounts for fluid flow, heat transfer, and deformation of the fractured reservoir. Flow through fractures is defined as two-dimensional laminar flow within the three-dimensional poroelastic medium. The local thermal non-equilibrium between injected CO2 and host reservoir has been considered with convective (conduction and advection) heat transfer. The numerical model has been developed using standard finite element method with Galerkin spatial discretisation, and finite difference temporal discretisation. The geomechanical model has been implemented into the object-oriented Imperial College Geomechanics Toolkit, in close interaction with the Complex Systems Modelling Platform (CSMP), and validated with several benchmark examples. Fifteen major faults are mapped from the Goldeneye field into the model. Modal stress intensity factors, for the three modes of fracture opening during hydrocarbon production and CO2 injection phases, are computed at the tips of the faults by computing the I-Integral over a virtual disk. Contact stresses -normal and shear- on the fault surfaces are iteratively computed using a gap-based augmented Lagrangian-Uzawa method. Results show fault activation during the production phase that may affect the fault's hydraulic conductivity and its connection to the reservoir rocks. The direction of growth is downward during production and it is expected to be upward during injection. Elevated fluid pressures inside faults during CO2 injection may further facilitate fault activation by reducing normal effective stresses. Activated faults can act as permeable conduits and potentially jeopardise caprock integrity for CO2 storage purposes.

Simultaneous estimation of local-scale and flow path-scale dual-domain mass transfer parameters using geoelectrical monitoring

USGS Publications Warehouse

Briggs, Martin A.; Day-Lewis, Frederick D.; Ong, John B.; Curtis, Gary P.; Lane, John W.

2013-01-01

Anomalous solute transport, modeled as rate-limited mass transfer, has an observable geoelectrical signature that can be exploited to infer the controlling parameters. Previous experiments indicate the combination of time-lapse geoelectrical and fluid conductivity measurements collected during ionic tracer experiments provides valuable insight into the exchange of solute between mobile and immobile porosity. Here, we use geoelectrical measurements to monitor tracer experiments at a former uranium mill tailings site in Naturita, Colorado. We use nonlinear regression to calibrate dual-domain mass transfer solute-transport models to field data. This method differs from previous approaches by calibrating the model simultaneously to observed fluid conductivity and geoelectrical tracer signals using two parameter scales: effective parameters for the flow path upgradient of the monitoring point and the parameters local to the monitoring point. We use regression statistics to rigorously evaluate the information content and sensitivity of fluid conductivity and geophysical data, demonstrating multiple scales of mass transfer parameters can simultaneously be estimated. Our results show, for the first time, field-scale spatial variability of mass transfer parameters (i.e., exchange-rate coefficient, porosity) between local and upgradient effective parameters; hence our approach provides insight into spatial variability and scaling behavior. Additional synthetic modeling is used to evaluate the scope of applicability of our approach, indicating greater range than earlier work using temporal moments and a Lagrangian-based Damköhler number. The introduced Eulerian-based Damköhler is useful for estimating tracer injection duration needed to evaluate mass transfer exchange rates that range over several orders of magnitude.

Subsurface storage of freshwater in South Florida; a digital analysis of recoverability

USGS Publications Warehouse

Merritt, Michael L.

1983-01-01

As part of a feasibility study of cyclic freshwater injection, digital models were implemented to analyze the relation of recovery efficiency to various hydrogeologic conditions which could prevail in brackish aquifers and to various management regimes. The analyses implemented an approach in which the control for sensitivity testing was a hypothetical aquifer representative of potential injection zones in south Florida, and parameter variations in sensitivity tests represented possible variations in aquifer conditions in the area. The permeability of the aquifer determined whether buoyancy stratification could reduce recovery efficiency. The range of permeability leading to buoyancy stratification became lower as resident fluid salinity increased. Thus, recovery efficiency was optimized by both low permeability and low resident fluid density. High levels of simulated hydrodynamic dispersion led to the lowest estimates of recovery efficiency. Advection by regional flow within the artesian injection zone could significantly affect recovery efficiency, depending upon the storage period, the volume injected, and site-specific hydraulic characteristics. Recovery efficiency was unrelated to the rate of injection or withdrawal or to the degree of penetration of permeable layers, and improved with successive cycles of injection and recovery. (USGS)

Stationary to nonstationary transition in crossed-field devices

DOE Office of Scientific and Technical Information (OSTI.GOV)

Marini, Samuel; Rizzato, Felipe B.; Pakter, Renato

2016-03-15

The previous results based on numerical simulations showed that a cold electron beam injected in a crossed field gap does not reach a time independent stationary state in the space charge limited regime [P. J. Christenson and Y. Y. Lau, Phys. Plasmas 1, 3725 (1994)]. In this work, the effect of finite injection temperature in the transition from stationary to nonstationary states is investigated. A fully kinetic model for the electron flow is derived and used to determine the possible stationary states of the system. It is found that although there is always a stationary solution for any set ofmore » parameters, depending on the injection temperature the electron flow becomes very sensitive to fluctuations and the stationary state is never reached. By investigating the nonlinear dynamics of a characteristic electron, a theory based on a single free parameter is constructed to predict when the transition between stationary and nonstationary states occurs. In agreement with the previous numerical results, the theory indicates that for vanishing temperatures the system never reaches the time independent stationary state in the space charge limited regime. Nevertheless, as the injection temperature is raised it is found a broad range of system parameters for which the stationary state is indeed attained. By properly adjusting the free parameter in the theory, one can be able to describe, to a very good accuracy, when the transition occurs.« less

CAE for Injection Molding — Past, Present and the Future

NASA Astrophysics Data System (ADS)

Wang, Kuo K.

2004-06-01

It is well known that injection molding is the most effective process for mass-producing discrete plastic parts of complex shape to the highest precision at the lowest cost. However, due to the complex property of polymeric materials undergoing a transient non-isothermal process, it is equally well recognized that the quality of final products is often difficult to be assured. This is particularly true when a new mold or material is encountered. As a result, injection molding has often been viewed as an art than a science. During the past few decades, numerical simulation of injection molding process based on analytic models has become feasible for practical use as computers became faster and cheaper continually. A research effort was initiated at the Cornell Injection Molding Program (CIMP) in 1974 under a grant from the National Science Foundation. Over a quarter of the century, CIMP has established some scientific bases ranging from materials characterization, flow analysis, to prediction of part quality. Use of such CAE tools has become common place today in industry. Present effort has been primarily aimed at refinements of many aspects of the process. Computational efficiency and user-interface have been main thrusts by commercial software developers. Extension to 3-dimensional flow analysis for certain parts has drawn some attention. Research activities are continuing on molding of fiber-filled materials and reactive polymers. Expanded molding processes such as gas-assisted, co-injection, micro-molding and many others are continually being investigated. In the future, improvements in simulation accuracy and efficiency will continue. This will include in-depth studies on materials characterization. Intelligent on-line process control may draw more attention in order to achieve higher degree of automation. As Internet technology continues to evolve, Web-based CAE tools for design, production, remote process monitoring and control can come to path. The CAE tools will eventually be integrated into an Enterprise Resources Planning (ERP) system as the trend of enterprise globalization continues.

Optimization and evaluation of asymmetric flow field-flow fractionation of silver nanoparticles.

PubMed

Loeschner, Katrin; Navratilova, Jana; Legros, Samuel; Wagner, Stephan; Grombe, Ringo; Snell, James; von der Kammer, Frank; Larsen, Erik H

2013-01-11

Asymmetric flow field-flow fractionation (AF(4)) in combination with on-line optical detection and mass spectrometry is one of the most promising methods for separation and quantification of nanoparticles (NPs) in complex matrices including food. However, to obtain meaningful results regarding especially the NP size distribution a number of parameters influencing the separation need to be optimized. This paper describes the development of a separation method for polyvinylpyrrolidone-stabilized silver nanoparticles (AgNPs) in aqueous suspension. Carrier liquid composition, membrane material, cross flow rate and spacer height were shown to have a significant influence on the recoveries and retention times of the nanoparticles. Focus time and focus flow rate were optimized with regard to minimum elution of AgNPs in the void volume. The developed method was successfully tested for injected masses of AgNPs from 0.2 to 5.0 μg. The on-line combination of AF(4) with detection methods including ICP-MS, light absorbance and light scattering was helpful because each detector provided different types of information about the eluting NP fraction. Differences in the time-resolved appearance of the signals obtained by the three detection methods were explained based on the physical origin of the signal. Two different approaches for conversion of retention times of AgNPs to their corresponding sizes and size distributions were tested and compared, namely size calibration with polystyrene nanoparticles (PSNPs) and calculations of size based on AF(4) theory. Fraction collection followed by transmission electron microscopy was performed to confirm the obtained size distributions and to obtain further information regarding the AgNP shape. Characteristics of the absorbance spectra were used to confirm the presence of non-spherical AgNP. Copyright © 2012 Elsevier B.V. All rights reserved.

Development of an analytical solution for thermal single-well injection-withdrawal tests in horizontally fractured reservoirs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jung, Yoojin

In this study, we have developed an analytical solution for thermal single-well injection-withdrawal tests in horizontally fractured reservoirs where fluid flow through the fracture is radial. The dimensionless forms of the governing equations and the initial and boundary conditions in the radial flow system can be written in a form identical to those in the linear flow system developed by Jung and Pruess [Jung, Y., and K. Pruess (2012), A Closed-Form Analytical Solution for Thermal Single-Well Injection-Withdrawal Tests, Water Resour. Res., 48, W03504, doi:10.1029/2011WR010979], and therefore the analytical solutions developed in Jung and Pruess (2012) can be applied to computemore » the time dependence of temperature recovery at the injection/withdrawal well in a horizontally oriented fracture with radial flow.« less

Investigation of transport process involved in FGD. Final repot, September 1, 1993--August 31, 1994

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kadambi, J.R.; Tien, J.S.; Yurteri, C.

1995-02-01

The objectives of this five year plan of study are to experimentally obtain a basic understanding of (1) turbulent flow structure of the mixing zone and it influence on particle dispersion, (2) the effect of particle loading on turbulent properties and mixing, (3) the effect of jet entrainment, (4) water spray-sorbent interaction, sorbent wetting and mixing, (5) investigate the flow field where certain ratios of jet velocity to flu gas velocity result in regions of negative flow and define onset o negative flow, and (6) sorbent reactivity in immediate mixing zone. In the first two years of the project amore » sorbent injection facility which can simulate the conditions encountered in COOLSIDE set up was designed and built. Non-intrusive laser based diagnostic tools PDA/LDA were used for flow characterization of particle laden jet in cocurrent flows. In the third year a new technique called TTLDV which combines particle transit time in measurement volume of LDV and LDV velocity measurements to simultaneously obtain non-spherical lime particle size and velocity was developed. Better sorbent injection schemes were investigated spray occurrent flow tests were conducted. During the fourth year the spray cocurrent flow interaction data was analyzed. A criterion was developed for predicting the flow reversal which results in deposition of water droplets on the duct wall (Table 3). The flow reversal occurs when the spray has entrained all the cocurrent flowing stream. The criterion is based upon the mass flow rate of the two phases. The criterion successfully predicted the flow reversals encountered in the experiments and will be a very useful practical tool. Lime laden jet occurrent flow interactions tests were completed. Tests on the swirling nozzle have been conducted. The single phase data have been analyzed while the two phase glass particle laden jet data is being analyzed.« less

Bioremediation in fractured rock: 1. Modeling to inform design, monitoring, and expectations

USGS Publications Warehouse

Tiedeman, Claire; Shapiro, Allen M.; Hsieh, Paul A.; Imbrigiotta, Thomas; Goode, Daniel J.; Lacombe, Pierre; DeFlaun, Mary F.; Drew, Scott R.; Johnson, Carole D.; Williams, John H.; Curtis, Gary P.

2018-01-01

Field characterization of a trichloroethene (TCE) source area in fractured mudstones produced a detailed understanding of the geology, contaminant distribution in fractures and the rock matrix, and hydraulic and transport properties. Groundwater flow and chemical transport modeling that synthesized the field characterization information proved critical for designing bioremediation of the source area. The planned bioremediation involved injecting emulsified vegetable oil and bacteria to enhance the naturally occurring biodegradation of TCE. The flow and transport modeling showed that injection will spread amendments widely over a zone of lower‐permeability fractures, with long residence times expected because of small velocities after injection and sorption of emulsified vegetable oil onto solids. Amendments transported out of this zone will be diluted by groundwater flux from other areas, limiting bioremediation effectiveness downgradient. At nearby pumping wells, further dilution is expected to make bioremediation effects undetectable in the pumped water. The results emphasize that in fracture‐dominated flow regimes, the extent of injected amendments cannot be conceptualized using simple homogeneous models of groundwater flow commonly adopted to design injections in unconsolidated porous media (e.g., radial diverging or dipole flow regimes). Instead, it is important to synthesize site characterization information using a groundwater flow model that includes discrete features representing high‐ and low‐permeability fractures. This type of model accounts for the highly heterogeneous hydraulic conductivity and groundwater fluxes in fractured‐rock aquifers, and facilitates designing injection strategies that target specific volumes of the aquifer and maximize the distribution of amendments over these volumes.

Optimal-mass-transfer-based estimation of glymphatic transport in living brain

NASA Astrophysics Data System (ADS)

Ratner, Vadim; Zhu, Liangjia; Kolesov, Ivan; Nedergaard, Maiken; Benveniste, Helene; Tannenbaum, Allen

2015-03-01

It was recently shown that the brain-wide cerebrospinal fluid (CSF) and interstitial fluid exchange system designated the `glymphatic pathway' plays a key role in removing waste products from the brain, similarly to the lymphatic system in other body organs . It is therefore important to study the flow patterns of glymphatic transport through the live brain in order to better understand its functionality in normal and pathological states. Unlike blood, the CSF does not flow rapidly through a network of dedicated vessels, but rather through para-vascular channels and brain parenchyma in a slower time-domain, and thus conventional fMRI or other blood-flow sensitive MRI sequences do not provide much useful information about the desired flow patterns. We have accordingly analyzed a series of MRI images, taken at different times, of the brain of a live rat, which was injected with a paramagnetic tracer into the CSF via the lumbar intrathecal space of the spine. Our goal is twofold: (a) find glymphatic (tracer) flow directions in the live rodent brain; and (b) provide a model of a (healthy) brain that will allow the prediction of tracer concentrations given initial conditions. We model the liquid flow through the brain by the diffusion equation. We then use the Optimal Mass Transfer (OMT) approach to derive the glymphatic flow vector field, and estimate the diffusion tensors by analyzing the (changes in the) flow. Simulations show that the resulting model successfully reproduces the dominant features of the experimental data. Keywords: inverse problem, optimal mass transport, diffusion equation, cerebrospinal fluid flow in brain, optical flow, liquid flow modeling, Monge Kantorovich problem, diffusion tensor estimation

A Computer Program for Flow-Log Analysis of Single Holes (FLASH)

USGS Publications Warehouse

Day-Lewis, F. D.; Johnson, C.D.; Paillet, Frederick L.; Halford, K.J.

2011-01-01

A new computer program, FLASH (Flow-Log Analysis of Single Holes), is presented for the analysis of borehole vertical flow logs. The code is based on an analytical solution for steady-state multilayer radial flow to a borehole. The code includes options for (1) discrete fractures and (2) multilayer aquifers. Given vertical flow profiles collected under both ambient and stressed (pumping or injection) conditions, the user can estimate fracture (or layer) transmissivities and far-field hydraulic heads. FLASH is coded in Microsoft Excel with Visual Basic for Applications routines. The code supports manual and automated model calibration. ?? 2011, The Author(s). Ground Water ?? 2011, National Ground Water Association.

Short-term efficacy of sacroiliac joint corticosteroid injection based on arthrographic contrast patterns.

PubMed

Scholten, Paul M; Patel, Shounuck I; Christos, Paul J; Singh, Jaspal R

2015-04-01

To determine the relationship between sacroiliac joint (SIJ) contrast dispersal patterns during SIJ corticosteroid injection and pain relief at 2 and 8 weeks after the procedure. The association between the number of positive provocative SIJ physical examination maneuvers (minimum of one in all patients undergoing SIJ injection) and the patient's response to the intervention was also assessed. Retrospective chart review. Academic outpatient musculoskeletal practice. Fifty-four subjects who underwent therapeutic SIJ corticosteroid injection were screened for inclusion; 49 subjects were included in the final analysis. A retrospective review of electronic medical records identified patients who underwent SIJ corticosteroid injection. Fluoroscopic contrast flow patterns were categorized as type I (intra-articular injection with cephalad extension within the SIJ) or type II (intra-articular injection with poor cephalad extension). Self-reported numeric pain rating scale (NPRS) values at the time of injection and 2 and 8 weeks after the procedure were recorded. The number of positive provocative SIJ physical examination maneuvers at the time of the initial evaluation was also recorded. The primary outcome measure was the effect of contrast patterns (type I or type II) on change in NPRS values at 2 weeks and 8 weeks after the injection. The secondary outcome measure was the association between the number of positive provocative SIJ physical examination maneuvers and decrease in the level of pain after the procedure. At 2 weeks after the procedure, type I subjects demonstrated a significantly lower mean NPRS value compared with type II subjects (2.8 ± 1.4 versus 3.8 ± 1.6, respectively, P = .02). No statistically significant difference was observed at 8 weeks after the procedure. NPRS values were significantly reduced both at 2 weeks and 8 weeks, compared with baseline, in both subjects identified as having type I flow and those with type II flow (P < .0001 for all within-group comparisons). Fluoroscopically guided corticosteroid injections into the SIJ joint are effective in decreasing NPRS values in patients with SIJ-mediated pain. Delivery of corticosteroid to the superior portion of the SIJ leads to a greater reduction in pain at 2 weeks, but not at 8 weeks. Patients with at least one positive provocative maneuver should benefit from an intra-articular corticosteroid injection. Copyright © 2015 American Academy of Physical Medicine and Rehabilitation. Published by Elsevier Inc. All rights reserved.

Detection of small degree of nonuniformity in dialysate flow in hollow-fiber dialyzer using proton magnetic resonance imaging.

PubMed

Osuga, T; Obata, T; Ikehira, H

2004-04-01

A small degree of nonuniformity in dialysate flow in a hollow-fiber dialyzer was detected using proton magnetic resonance imaging (MRI). Since paramagnetic ions reduce the spin-lattice relaxation time of protons around them, MRI can detect Gd in water. An aqueous solution of a chelate compound of Gd was impulsively injected into the dialysate flow path at a flow rate of 500 cm(3) /m, which is that utilized in actual dialysis. Despite the apparent elimination of Gd from the dialysate flow path by the newly injected dialysate fluid after the injection of Gd was terminated, MRI revealed that Gd remained in the interior of the hollow fiber. The observed structure pattern of the Gd concentration profile revealed that the dialysate flow had a small degree of nonuniformity despite the currently established design to restrict channeling in dialysate flow. Local nonuniformity of the hollow-fiber density and vortex generation in the dialysate flow were considered to cause the nonuniformity in the dialysate flow.

Unsteady separation and vortex shedding from a laminar separation bubble over a bluff body

NASA Astrophysics Data System (ADS)

Das, S. P.; Srinivasan, U.; Arakeri, J. H.

2013-07-01

Boundary layers are subject to favorable and adverse pressure gradients because of both the temporal and spatial components of the pressure gradient. The adverse pressure gradient may cause the flow to separate. In a closed loop unsteady tunnel we have studied the initiation of separation in unsteady flow past a constriction (bluff body) in a channel. We have proposed two important scalings for the time when boundary layer separates. One is based on the local pressure gradient and the other is a convective time scale based on boundary layer parameters. The flow visualization using a dye injection technique shows the flow structure past the body. Nondimensional shedding frequency (Strouhal number) is calculated based on boundary layer and momentum thicknesses. Strouhal number based on the momentum thickness shows a close agreement with that for flat plate and circular cylinder.

Study of the motion and deposition of micro particles in a vertical tube containing uniform gas flow

NASA Astrophysics Data System (ADS)

Abolpour, Bahador; Afsahi, M. Mehdi; Soltani Goharrizi, Ataallah; Azizkarimi, Mehdi

2017-12-01

In this study, effects of a gaseous jet, formed in a vertical tube containing a uniform gas flow, on the injected micro particles have been investigated. A CFD model has been developed to simulate the particle motion in the tube. This simulation is very close to the experimental data. The results show that, increasing the flow rate of carrier gas or decreasing the flow rate of surrounding gas increases the effect of gaseous jet and also increases trapping rate of the particles by the tube wall. The minimum and maximum residence times of particles approach together with increasing the size of solid particles. Particles larger than 60 μm have a certain and fixed residence time at different flow rates of the carrier or surrounding gas. About 40 μm particle size has minimal trapping by the tube wall at various experimental conditions.

COUPLING THE ALKALINE-SURFACTANT-POLYMER TECHNOLOGY AND THE GELATION TECHNOLOGY TO MAXIMIZE OIL PRODUCTION

DOE Office of Scientific and Technical Information (OSTI.GOV)

Malcolm Pitts; Jie Qi; Dan Wilson

2005-04-01

Gelation technologies have been developed to provide more efficient vertical sweep efficiencies for flooding naturally fractured oil reservoirs or more efficient areal sweep efficiency for those with high permeability contrast ''thief zones''. The field proven alkaline-surfactant-polymer technology economically recovers 15% to 25% OOIP more oil than waterflooding from swept pore space of an oil reservoir. However, alkaline-surfactant-polymer technology is not amenable to naturally fractured reservoirs or those with thief zones because much of injected solution bypasses target pore space containing oil. This work investigates whether combining these two technologies could broaden applicability of alkaline-surfactant-polymer flooding into these reservoirs. A priormore » fluid-fluid report discussed interaction of different gel chemical compositions and alkaline-surfactant-polymer solutions. Gel solutions under dynamic conditions of linear corefloods showed similar stability to alkaline-surfactant-polymer solutions as in the fluid-fluid analyses. Aluminum-polyacrylamide, flowing gels are not stable to alkaline-surfactant-polymer solutions of either pH 10.5 or 12.9. Chromium acetate-polyacrylamide flowing and rigid flowing gels are stable to subsequent alkaline-surfactant-polymer solution injection. Rigid flowing chromium acetate-polyacrylamide gels maintained permeability reduction better than flowing chromium acetate-polyacrylamide gels. Silicate-polyacrylamide gels are not stable with subsequent injection of either a pH 10.5 or a 12.9 alkaline-surfactant-polymer solution. Chromium acetate-xanthan gum rigid gels are not stable to subsequent alkaline-surfactant-polymer solution injection. Resorcinol-formaldehyde gels were stable to subsequent alkaline-surfactant-polymer solution injection. When evaluated in a dual core configuration, injected fluid flows into the core with the greatest effective permeability to the injected fluid. The same gel stability trends to subsequent alkaline-surfactant-polymer injected solution were observed. Aluminum citrate-polyacrylamide, resorcinol-formaldehyde, and the silicate-polyacrylamide gel systems did not produce significant incremental oil in linear corefloods. Both flowing and rigid flowing chromium acetate-polyacrylamide gels and the xanthan gum-chromium acetate gel system produced incremental oil with the rigid flowing gel producing the greatest amount. Higher oil recovery could have been due to higher differential pressures across cores. None of the gels tested appeared to alter alkaline-surfactant-polymer solution oil recovery. Total waterflood plus chemical flood oil recovery sequence recoveries were all similar.« less

Bubble Formation from Wall Orifice in Liquid Cross-Flow Under Low Gravity

NASA Technical Reports Server (NTRS)

Nahra, Henry K.; Kamotani, Y.

2000-01-01

Two-phase flows present a wide variety of applications for spacecraft thermal control systems design. Bubble formation and detachment is an integral part of the two phase flow science. The objective of the present work is to experimentally investigate the effects of liquid cross-flow velocity, gas flow rate, and orifice diameter on bubble formation in a wall-bubble injection configuration. Data were taken mainly under reduced gravity conditions but some data were taken in normal gravity for comparison. The reduced gravity experiment was conducted aboard the NASA DC-9 Reduced Gravity Aircraft. The results show that the process of bubble formation and detachment depends on gravity, the orifice diameter, the gas flow rate, and the liquid cross-flow velocity. The data are analyzed based on a force balance, and two different detachment mechanisms are identified. When the gas momentum is large, the bubble detaches from the injection orifice as the gas momentum overcomes the attaching effects of liquid drag and inertia. The surface tension force is much reduced because a large part of the bubble pinning edge at the orifice is lost as the bubble axis is tilted by the liquid flow. When the gas momentum is small, the force balance in the liquid flow direction is important, and the bubble detaches when the bubble axis inclination exceeds a certain angle.

Simplified Predictive Models for CO2 Sequestration Performance Assessment

NASA Astrophysics Data System (ADS)

Mishra, Srikanta; RaviGanesh, Priya; Schuetter, Jared; Mooney, Douglas; He, Jincong; Durlofsky, Louis

2014-05-01

We present results from an ongoing research project that seeks to develop and validate a portfolio of simplified modeling approaches that will enable rapid feasibility and risk assessment for CO2 sequestration in deep saline formation. The overall research goal is to provide tools for predicting: (a) injection well and formation pressure buildup, and (b) lateral and vertical CO2 plume migration. Simplified modeling approaches that are being developed in this research fall under three categories: (1) Simplified physics-based modeling (SPM), where only the most relevant physical processes are modeled, (2) Statistical-learning based modeling (SLM), where the simulator is replaced with a "response surface", and (3) Reduced-order method based modeling (RMM), where mathematical approximations reduce the computational burden. The system of interest is a single vertical well injecting supercritical CO2 into a 2-D layered reservoir-caprock system with variable layer permeabilities. In the first category (SPM), we use a set of well-designed full-physics compositional simulations to understand key processes and parameters affecting pressure propagation and buoyant plume migration. Based on these simulations, we have developed correlations for dimensionless injectivity as a function of the slope of fractional-flow curve, variance of layer permeability values, and the nature of vertical permeability arrangement. The same variables, along with a modified gravity number, can be used to develop a correlation for the total storage efficiency within the CO2 plume footprint. In the second category (SLM), we develop statistical "proxy models" using the simulation domain described previously with two different approaches: (a) classical Box-Behnken experimental design with a quadratic response surface fit, and (b) maximin Latin Hypercube sampling (LHS) based design with a Kriging metamodel fit using a quadratic trend and Gaussian correlation structure. For roughly the same number of simulations, the LHS-based meta-model yields a more robust predictive model, as verified by a k-fold cross-validation approach. In the third category (RMM), we use a reduced-order modeling procedure that combines proper orthogonal decomposition (POD) for reducing problem dimensionality with trajectory-piecewise linearization (TPWL) for extrapolating system response at new control points from a limited number of trial runs ("snapshots"). We observe significant savings in computational time with very good accuracy from the POD-TPWL reduced order model - which could be important in the context of history matching, uncertainty quantification and optimization problems. The paper will present results from our ongoing investigations, and also discuss future research directions and likely outcomes. This work was supported by U.S. Department of Energy National Energy Technology Laboratory award DE-FE0009051 and Ohio Department of Development grant D-13-02.

Fuel Injector With Shear Atomizer

NASA Technical Reports Server (NTRS)

Beal, George W.; Mills, Virgil L.; Smith, Durward B., II; Beacom, William F.

1995-01-01

Atomizer for injecting liquid fuel into combustion chamber uses impact and swirl to break incoming stream of fuel into small, more combustible droplets. Slanted holes direct flow of liquid fuel to stepped cylindrical wall. Impact on wall atomizes liquid. Air flowing past vanes entrains droplets of liquid in swirling flow. Fuel injected at pressure lower than customarily needed.