The importance of flow history in mixed shear and extensional flows

NASA Astrophysics Data System (ADS)

Wagner, Caroline; McKinley, Gareth

2015-11-01

Many complex fluid flows of experimental and academic interest exhibit mixed kinematics with regions of shear and elongation. Examples include flows through planar hyperbolic contractions in microfluidic devices and through porous media or geometric arrays. Through the introduction of a ``flow-type parameter'' α which varies between 0 in pure shear and 1 in pure elongation, the local velocity fields of all such mixed flows can be concisely characterized. It is tempting to then consider the local stress field and interpret the local state of stress in a complex fluid in terms of shearing or extensional material functions. However, the material response of such fluids exhibit a fading memory of the entire deformation history. We consider a dilute solution of Hookean dumbbells and solve the Oldroyd-B model to obtain analytic expressions for the entire stress field in any arbitrary mixed flow of constant strain rate and flow-type parameter α. We then consider a more complex flow for which the shear rate is constant but the flow-type parameter α varies periodically in time (reminiscent of flow through a periodic array or through repeated contractions and expansions). We show that the flow history and kinematic sequencing (in terms of whether the flow was initialized as shearing or extensional) is extremely important in determining the ensuing stress field and rate of dissipated energy in the flow, and can only be ignored in the limit of infinitely slow flow variations.

Local thermodynamic equilibrium for globally disequilibrium open systems under stress

NASA Astrophysics Data System (ADS)

Podladchikov, Yury

2016-04-01

Predictive modeling of far and near equilibrium processes is essential for understanding of patterns formation and for quantifying of natural processes that are never in global equilibrium. Methods of both equilibrium and non-equilibrium thermodynamics are needed and have to be combined. For example, predicting temperature evolution due to heat conduction requires simultaneous use of equilibrium relationship between internal energy and temperature via heat capacity (the caloric equation of state) and disequilibrium relationship between heat flux and temperature gradient. Similarly, modeling of rocks deforming under stress, reactions in system open for the porous fluid flow, or kinetic overstepping of the equilibrium reaction boundary necessarily needs both equilibrium and disequilibrium material properties measured under fundamentally different laboratory conditions. Classical irreversible thermodynamics (CIT) is the well-developed discipline providing the working recipes for the combined application of mutually exclusive experimental data such as density and chemical potential at rest under constant pressure and temperature and viscosity of the flow under stress. Several examples will be presented.

Sperm Motility in Flow

NASA Astrophysics Data System (ADS)

Guasto, Jeffrey; Juarez, Gabriel; Stocker, Roman

2012-11-01

A wide variety of plants and animals reproduce sexually by releasing motile sperm that seek out a conspecific egg, for example in the reproductive tract for mammals or in the water column for externally fertilizing organisms. Sperm are aided in their quest by chemical cues, but must also contend with hydrodynamic forces, resulting from laminar flows in reproductive tracts or turbulence in aquatic habitats. To understand how velocity gradients affect motility, we subjected swimming sperm to a range of highly-controlled straining flows using a cross-flow microfluidic device. The motion of the cell body and flagellum were captured through high-speed video microscopy. The effects of flow on swimming are twofold. For moderate velocity gradients, flow simply advects and reorients cells, quenching their ability to cross streamlines. For high velocity gradients, fluid stresses hinder the internal bending of the flagellum, directly inhibiting motility. The transition between the two regimes is governed by the Sperm number, which compares the external viscous stresses with the internal elastic stresses. Ultimately, unraveling the role of flow in sperm motility will lead to a better understanding of population dynamics among aquatic organisms and infertility problems in humans.

Direct measurements of bed stress under swash in the field

NASA Astrophysics Data System (ADS)

Conley, Daniel C.; Griffin, John G.

2004-03-01

Utilizing flush mounted hot film anemometry, the bed stress under swash was measured directly in a field experiment conducted on Barret Beach, Fire Island, New York. The theory, development, and calibration of the instrument package are discussed, and results from the field experiment are presented. Examples of bed stress time series throughout a swash cycle are presented, and an ensemble averaged swash bed stress cycle is calculated. Strong asymmetry is observed between the uprush and backwash phases of the swash flow. The maximum bed shear stress exerted by the uprush is approximately double that of the backwash, while the duration of the backwash is 135% greater than that of the uprush. Friction coefficients in the swash zone are observed to be similar in magnitude to those from steady flow, with the mean observed friction coefficient equal to 0.0037. Swash friction coefficients derived from the current measurements exhibit a Reynolds number dependence similar to that observed for other flows. A systematic difference between coefficients for uprush and backwash is suggested.

Computational analysis of integrated biosensing and shear flow in a microfluidic vascular model

NASA Astrophysics Data System (ADS)

Wong, Jeremy F.; Young, Edmond W. K.; Simmons, Craig A.

2017-11-01

Fluid flow and flow-induced shear stress are critical components of the vascular microenvironment commonly studied using microfluidic cell culture models. Microfluidic vascular models mimicking the physiological microenvironment also offer great potential for incorporating on-chip biomolecular detection. In spite of this potential, however, there are few examples of such functionality. Detection of biomolecules released by cells under flow-induced shear stress is a significant challenge due to severe sample dilution caused by the fluid flow used to generate the shear stress, frequently to the extent where the analyte is no longer detectable. In this work, we developed a computational model of a vascular microfluidic cell culture model that integrates physiological shear flow and on-chip monitoring of cell-secreted factors. Applicable to multilayer device configurations, the computational model was applied to a bilayer configuration, which has been used in numerous cell culture applications including vascular models. Guidelines were established that allow cells to be subjected to a wide range of physiological shear stress while ensuring optimal rapid transport of analyte to the biosensor surface and minimized biosensor response times. These guidelines therefore enable the development of microfluidic vascular models that integrate cell-secreted factor detection while addressing flow constraints imposed by physiological shear stress. Ultimately, this work will result in the addition of valuable functionality to microfluidic cell culture models that further fulfill their potential as labs-on-chips.

Constructal vascularized structures

NASA Astrophysics Data System (ADS)

Cetkin, Erdal

2015-06-01

Smart features such as self-healing and selfcooling require bathing the entire volume with a coolant or/and healing agent. Bathing the entire volume is an example of point to area (or volume) flows. Point to area flows cover all the distributing and collecting kinds of flows, i.e. inhaling and exhaling, mining, river deltas, energy distribution, distribution of products on the landscape and so on. The flow resistances of a point to area flow can be decreased by changing the design with the guidance of the constructal law, which is the law of the design evolution in time. In this paper, how the flow resistances (heat, fluid and stress) can be decreased by using the constructal law is shown with examples. First, the validity of two assumptions is surveyed: using temperature independent Hess-Murray rule and using constant diameter ducts where the duct discharges fluid along its edge. Then, point to area types of flows are explained by illustrating the results of two examples: fluid networks and heating an area. Last, how the structures should be vascularized for cooling and mechanical strength is documented. This paper shows that flow resistances can be decreased by morphing the shape freely without any restrictions or generic algorithms.

Intracellular pH changes in human aortic smooth muscle cells in response to fluid shear stress

NASA Technical Reports Server (NTRS)

Stamatas, G. N.; Patrick, C. W. Jr; McIntire, L. V.

1997-01-01

The smooth muscle cell (SMC) layers of human arteries may be exposed to blood flow after endothelium denudation, for example, following balloon angioplasty treatment. These SMCs are also constantly subjected to pressure driven transmural fluid flow. Flow-induced shear stress can alter SMC growth and metabolism. Signal transduction mechanisms involved in these flow effects on SMCs are still poorly understood. In this work, the hypothesis that shear stress alters the intracellular pH (pHi) of SMC is examined. When exposed to venous and arterial levels of shear stress, human aortic smooth muscle cells (hASMC) undergo alkalinization. The alkalinization plateau persisted even after 20 min of cell exposure to flow. Addition of amiloride (10 micromoles) or its 5-(N-ethyl-N-isopropyl) analog (EIPA, 10 micromoles), both Na+/H+ exchanger inhibitors, attenuated intracellular alkalinization, suggesting the involvement of the Na+/H+ exchanger in this response. The same concentrations of these inhibitors did not show an effect on pHi of hASMCs in static culture. 4-Acetamido-4'-isothio-cyanatostilbene-2,2'-disulfonic acid (SITS, 1 mM), a Cl-/HCO3- exchange inhibitor, affected the pHi of hASMCs both in static and flow conditions. Our results suggest that flow may perturb the Na+/H+ exchanger leading to an alkalinization of hASMCs, a different response from the flow-induced acidification seen with endothelial cells at the same levels of shear stress. Understanding the flow-induced signal transduction pathways in the vascular cells is of great importance in the tissue engineering of vascular grafts. In the case of SMCs, the involvement of pHi changes in nitric oxide production and proliferation regulation highlights further the significance of such studies.

A multiple-time-scale turbulence model based on variable partitioning of turbulent kinetic energy spectrum

NASA Technical Reports Server (NTRS)

Kim, S.-W.; Chen, C.-P.

1987-01-01

A multiple-time-scale turbulence model of a single point closure and a simplified split-spectrum method is presented. In the model, the effect of the ratio of the production rate to the dissipation rate on eddy viscosity is modeled by use of the multiple-time-scales and a variable partitioning of the turbulent kinetic energy spectrum. The concept of a variable partitioning of the turbulent kinetic energy spectrum and the rest of the model details are based on the previously reported algebraic stress turbulence model. Example problems considered include: a fully developed channel flow, a plane jet exhausting into a moving stream, a wall jet flow, and a weakly coupled wake-boundary layer interaction flow. The computational results compared favorably with those obtained by using the algebraic stress turbulence model as well as experimental data. The present turbulence model, as well as the algebraic stress turbulence model, yielded significantly improved computational results for the complex turbulent boundary layer flows, such as the wall jet flow and the wake boundary layer interaction flow, compared with available computational results obtained by using the standard kappa-epsilon turbulence model.

A multiple-time-scale turbulence model based on variable partitioning of the turbulent kinetic energy spectrum

NASA Technical Reports Server (NTRS)

Kim, S.-W.; Chen, C.-P.

1989-01-01

A multiple-time-scale turbulence model of a single point closure and a simplified split-spectrum method is presented. In the model, the effect of the ratio of the production rate to the dissipation rate on eddy viscosity is modeled by use of the multiple-time-scales and a variable partitioning of the turbulent kinetic energy spectrum. The concept of a variable partitioning of the turbulent kinetic energy spectrum and the rest of the model details are based on the previously reported algebraic stress turbulence model. Example problems considered include: a fully developed channel flow, a plane jet exhausting into a moving stream, a wall jet flow, and a weakly coupled wake-boundary layer interaction flow. The computational results compared favorably with those obtained by using the algebraic stress turbulence model as well as experimental data. The present turbulence model, as well as the algebraic stress turbulence model, yielded significantly improved computational results for the complex turbulent boundary layer flows, such as the wall jet flow and the wake boundary layer interaction flow, compared with available computational results obtained by using the standard kappa-epsilon turbulence model.

On the continuity of mean total normal stress in geometrical multiscale cardiovascular problems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Blanco, Pablo J., E-mail: pjblanco@lncc.br; INCT-MACC, Instituto Nacional de Ciência e Tecnologia em Medicina Assistida por Computação Científica, Petrópolis; Deparis, Simone, E-mail: simone.deparis@epfl.ch

2013-10-15

In this work an iterative strategy to implicitly couple dimensionally-heterogeneous blood flow models accounting for the continuity of mean total normal stress at interface boundaries is developed. Conservation of mean total normal stress in the coupling of heterogeneous models is mandatory to satisfy energetic consistency between them. Nevertheless, existing methodologies are based on modifications of the Navier–Stokes variational formulation, which are undesired when dealing with fluid–structure interaction or black box codes. The proposed methodology makes possible to couple one-dimensional and three-dimensional fluid–structure interaction models, enforcing the continuity of mean total normal stress while just imposing flow rate data or evenmore » the classical Neumann boundary data to the models. This is accomplished by modifying an existing iterative algorithm, which is also able to account for the continuity of the vessel area, when required. Comparisons are performed to assess differences in the convergence properties of the algorithms when considering the continuity of mean normal stress and the continuity of mean total normal stress for a wide range of flow regimes. Finally, examples in the physiological regime are shown to evaluate the importance, or not, of considering the continuity of mean total normal stress in hemodynamics simulations.« less

Model-based image analysis of a tethered Brownian fibre for shear stress sensing

PubMed Central

2017-01-01

The measurement of fluid dynamic shear stress acting on a biologically relevant surface is a challenging problem, particularly in the complex environment of, for example, the vasculature. While an experimental method for the direct detection of wall shear stress via the imaging of a synthetic biology nanorod has recently been developed, the data interpretation so far has been limited to phenomenological random walk modelling, small-angle approximation, and image analysis techniques which do not take into account the production of an image from a three-dimensional subject. In this report, we develop a mathematical and statistical framework to estimate shear stress from rapid imaging sequences based firstly on stochastic modelling of the dynamics of a tethered Brownian fibre in shear flow, and secondly on a novel model-based image analysis, which reconstructs fibre positions by solving the inverse problem of image formation. This framework is tested on experimental data, providing the first mechanistically rational analysis of the novel assay. What follows further develops the established theory for an untethered particle in a semi-dilute suspension, which is of relevance to, for example, the study of Brownian nanowires without flow, and presents new ideas in the field of multi-disciplinary image analysis. PMID:29212755

Dynamical Evaluation of Ocean Models Using the Gulf Stream as an Example

DTIC Science & Technology

2012-02-10

Hellerman and Rosenstein (1983) wind stress climatology and the northward upper ocean flow (14 Sv) of the Atlantic meridional overturning circulation ...30 35 55N 65N Fig. 21.14 Atlantic meridional overturning circulation (AMOC) streamfunction from the same four simulations as Fig. 21.11. An AMOC...typically develops a northern or southern bias. A shallow bias in the southward abyssal flow of the Atlan- tic Meridional Overturning Circulation (AMOC

A massively parallel computational approach to coupled thermoelastic/porous gas flow problems

NASA Technical Reports Server (NTRS)

Shia, David; Mcmanus, Hugh L.

1995-01-01

A new computational scheme for coupled thermoelastic/porous gas flow problems is presented. Heat transfer, gas flow, and dynamic thermoelastic governing equations are expressed in fully explicit form, and solved on a massively parallel computer. The transpiration cooling problem is used as an example problem. The numerical solutions have been verified by comparison to available analytical solutions. Transient temperature, pressure, and stress distributions have been obtained. Small spatial oscillations in pressure and stress have been observed, which would be impractical to predict with previously available schemes. Comparisons between serial and massively parallel versions of the scheme have also been made. The results indicate that for small scale problems the serial and parallel versions use practically the same amount of CPU time. However, as the problem size increases the parallel version becomes more efficient than the serial version.

Flow-induced adhesion of shear-activated polymers to a substrate

NASA Astrophysics Data System (ADS)

Hoore, Masoud; Rack, Kathrin; Fedosov, Dmitry A.; Gompper, Gerhard

2018-02-01

Adhesion of polymers and proteins to substrates plays a crucial role in many technological applications and biological processes. A prominent example is the von Willebrand factor (VWF) protein, which is essential in blood clotting as it mediates adhesion of blood platelets to the site of injury at high shear rates. VWF is activated by flow and is able to bind efficiently to damaged vessel walls even under extreme flow-stress conditions; however, its adhesion is reversible when the flow strength is significantly reduced or the flow is ceased. Motivated by the properties and behavior of VWF in flow, we investigate adhesion of shear-activated polymers to a planar wall in flow and whether the adhesion is reversible under flow stasis. The main ingredients of the polymer model are cohesive inter-monomer interactions, a catch bond with the adhesive surface, and the shear activation/deactivation of polymer adhesion correlated with its stretching in flow. The cohesive interactions within the polymer maintain a globular conformation under low shear stresses and allow polymer stretching if a critical shear rate is exceeded, which is directly associated with its activation for adhesion. Our results show that polymer adhesion at high shear rates is significantly stabilized by catch bonds, while at the same time they also permit polymer dissociation from a surface at low or no flow stresses. In addition, the activation/deactivation mechanism for adhesion plays a crucial role in the reversibility of its adhesion. These observations help us better understand the adhesive behavior of VWF in flow and interpret its adhesion malfunctioning in VWF-related diseases.

Human effects on the hydrologic system of the Verde Valley, central Arizona, 1910–2005 and 2005–2110, using a regional groundwater flow model

USGS Publications Warehouse

Garner, Bradley D.; Pool, D.R.; Tillman, Fred D.; Forbes, Brandon T.

2013-01-01

Water budgets were developed for the Verde Valley of central Arizona in order to evaluate the degree to which human stresses have affected the hydrologic system and might affect it in the future. The Verde Valley is a portion of central Arizona wherein concerns have been raised about water availability, particularly perennial base flow of the Verde River. The Northern Arizona Regional Groundwater Flow Model (NARGFM) was used to generate the water budgets and was run in several configurations for the 1910–2005 and 2005–2110 time periods. The resultant water budgets were subtracted from one another in order to quantify the relative changes that were attributable solely to human stresses; human stresses included groundwater withdrawals and incidental and artificial recharge but did not include, for example, human effects on the global climate. Three hypothetical and varied conditions of human stresses were developed and applied to the model for the 2005–2110 period. On the basis of this analysis, human stresses during 1910–2005 were found to have already affected the hydrologic system of the Verde Valley, and human stresses will continue to affect the hydrologic system during 2005–2110. Riparian evapotranspiration decreased and underflow into the Verde Valley increased because of human stresses, and net groundwater discharge to the Verde River in the Verde Valley decreased for the 1910–2005 model runs. The model also showed that base flow at the upstream end of the study area, as of 2005, was about 4,900 acre-feet per year less than it would have been in the absence of human stresses. At the downstream end of the Verde Valley, base flow had been reduced by about 10,000 acre-feet per year by the year 2005 because of human stresses. For the 2005–2110 period, the model showed that base flow at the downstream end of the Verde Valley may decrease by an additional 5,400 to 8,600 acre-feet per year because of past, ongoing, and hypothetical future human stresses. The process known as capture (or streamflow depletion caused by the pumping of groundwater) was the reason for these human-stress-induced changes in water-budget components.

Turbulent transport models for scramjet flowfields

NASA Technical Reports Server (NTRS)

Sindir, M. M.; Harsha, P. T.

1984-01-01

Turbulence modeling approaches were examined from the standpoint of their capability to predict the complex flowfield features observed in scramjet combustions. Thus, for example, the accuracy of each turbulence model, with respect to the prediction of recirculating flows, was examined. It was observed that for large diameter ratio axisymmetric sudden expansion flows, a choice of turbulence model was not critical because of the domination of their flowfields by pressure forces. For low diameter ratio axisymmetric sudden expansions and planar backward-facing steps flows, where turbulent shear stresses are of greater significance, the algebraic Reynolds stress approach, modified to increase its sensitivity to streamline curvature, was found to provide the best results. Results of the study also showed that strongly swirling flows provide a stringent test of turbulence model assumptions. Thus, although flows with very high swirl are not of great practical interest, they are useful for turbulence model development. Finally, it was also noted that numerical flowfields solution techniques have a strong interrelation with turbulence models, particularly with the turbulent transport models which involve source-dominated transport equations.

Wall shear stress fixed points in cardiovascular fluid mechanics.

PubMed

Arzani, Amirhossein; Shadden, Shawn C

2018-05-17

Complex blood flow in large arteries creates rich wall shear stress (WSS) vectorial features. WSS acts as a link between blood flow dynamics and the biology of various cardiovascular diseases. WSS has been of great interest in a wide range of studies and has been the most popular measure to correlate blood flow to cardiovascular disease. Recent studies have emphasized different vectorial features of WSS. However, fixed points in the WSS vector field have not received much attention. A WSS fixed point is a point on the vessel wall where the WSS vector vanishes. In this article, WSS fixed points are classified and the aspects by which they could influence cardiovascular disease are reviewed. First, the connection between WSS fixed points and the flow topology away from the vessel wall is discussed. Second, the potential role of time-averaged WSS fixed points in biochemical mass transport is demonstrated using the recent concept of Lagrangian WSS structures. Finally, simple measures are proposed to quantify the exposure of the endothelial cells to WSS fixed points. Examples from various arterial flow applications are demonstrated. Copyright © 2018 Elsevier Ltd. All rights reserved.

Critical assessment of Reynolds stress turbulence models using homogeneous flows

NASA Technical Reports Server (NTRS)

Shabbir, Aamir; Shih, Tsan-Hsing

1992-01-01

In modeling the rapid part of the pressure correlation term in the Reynolds stress transport equations, extensive use has been made of its exact properties which were first suggested by Rotta. These, for example, have been employed in obtaining the widely used Launder, Reece and Rodi (LRR) model. Some recent proposals have dropped one of these properties to obtain new models. We demonstrate, by computing some simple homogeneous flows, that doing so does not lead to any significant improvements over the LRR model and it is not the right direction in improving the performance of existing models. The reason for this, in our opinion, is that violation of one of the exact properties can not bring in any new physics into the model. We compute thirteen homogeneous flows using LRR (with a recalibrated rapid term constant), IP and SSG models. The flows computed include the flow through axisymmetric contraction; axisymmetric expansion; distortion by plane strain; and homogeneous shear flows with and without rotation. Results show that for most general representation for a model linear in the anisotropic tensor, performs either better or as good as the other two models of the same level.

The Use of DNS in Turbulence Modeling

NASA Technical Reports Server (NTRS)

Mansour, Nagi N.; Merriam, Marshal (Technical Monitor)

1997-01-01

The use of Direct numerical simulations (DNS) data in developing and testing turbulence models is reviewed. The data is used to test turbulence models at all levels: algebraic, one-equation, two-equation and full Reynolds stress models were tested. Particular examples on the development of models for the dissipation rate equation are presented. Homogeneous flows are used to test new scaling arguments for the various terms in the dissipation rate equation. The channel flow data is used to develop modifications to the equation model that take into account near-wall effects. DNS of compressible flows under mean compression are used in testing new compressible modifications to the two-equation models.

Using flowmeter pulse tests to define hydraulic connections in the subsurface: A fractured shale example

USGS Publications Warehouse

Williams, J.H.; Paillet, Frederick L.

2002-01-01

Cross-borehole flowmeter pulse tests define subsurface connections between discrete fractures using short stress periods to monitor the propagation of the pulse through the flow system. This technique is an improvement over other cross-borehole techniques because measurements can be made in open boreholes without packers or previous identification of water-producing intervals. The method is based on the concept of monitoring the propagation of pulses rather than steady flow through the fracture network. In this method, a hydraulic stress is applied to a borehole connected to a single, permeable fracture, and the distribution of flow induced by that stress monitored in adjacent boreholes. The transient flow responses are compared to type curves computed for several different types of fracture connections. The shape of the transient flow response indicates the type of fracture connection, and the fit of the data to the type curve yields an estimate of its transmissivity and storage coefficient. The flowmeter pulse test technique was applied in fractured shale at a volatile-organic contaminant plume in Watervliet, New York. Flowmeter and other geophysical logs were used to identify permeable fractures in eight boreholes in and near the contaminant plume using single-borehole flow measurements. Flowmeter cross-hole pulse tests were used to identify connections between fractures detected in the boreholes. The results indicated a permeable fracture network connecting many of the individual boreholes, and demonstrated the presence of an ambient upward hydraulic-head gradient throughout the site.

Acute vascular effects of carbonated warm water lower leg immersion in healthy young adults.

PubMed

Ogoh, Shigehiko; Nagaoka, Ryohei; Mizuno, Takamasa; Kimura, Shohei; Shidahara, Yasuhiro; Ishii, Tomomi; Kudoh, Michinari; Iwamoto, Erika

2016-12-01

Endothelial dysfunction is associated with increased cardiovascular mortality and morbidity; however, this dysfunction may be ameliorated by several therapies. For example, it has been reported that heat-induced increases in blood flow and shear stress enhance endothelium-mediated vasodilator function. Under these backgrounds, we expect that carbon dioxide (CO 2 )-rich water-induced increase in skin blood flow improves endothelium-mediated vasodilation with less heat stress. To test our hypothesis, we measured flow-mediated dilation (FMD) before and after acute immersion of the lower legs and feet in mild warm (38°C) normal or CO 2 -rich tap water (1000 ppm) for 20 min in 12 subjects. Acute immersion of the lower legs and feet in mild warm CO 2 -rich water increased FMD (P < 0.01) despite the lack of change in this parameter upon mild warm normal water immersion. In addition, FMD was positively correlated with change in skin blood flow regardless of conditions (P < 0.01), indicating that an increase in skin blood flow improves endothelial-mediated vasodilator function. Importantly, the temperature of normal tap water must reach approximately 43°C to achieve the same skin blood flow level as that obtained during mild warm CO 2 -rich water immersion (38°C). These findings suggest that CO 2 -rich water-induced large increases in skin blood flow may improve endothelial-mediated vasodilator function while causing less heat stress. © 2016 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society.

An upper bound on the particle-laden dependency of shear stresses at solid-fluid interfaces

NASA Astrophysics Data System (ADS)

Zohdi, T. I.

2018-03-01

In modern advanced manufacturing processes, such as three-dimensional printing of electronics, fine-scale particles are added to a base fluid yielding a modified fluid. For example, in three-dimensional printing, particle-functionalized inks are created by adding particles to freely flowing solvents forming a mixture, which is then deposited onto a surface, which upon curing yields desirable solid properties, such as thermal conductivity, electrical permittivity and magnetic permeability. However, wear at solid-fluid interfaces within the machinery walls that deliver such particle-laden fluids is typically attributed to the fluid-induced shear stresses, which increase with the volume fraction of added particles. The objective of this work is to develop a rigorous strict upper bound for the tolerable volume fraction of particles that can be added, while remaining below a given stress threshold at a fluid-solid interface. To illustrate the bound's utility, the expression is applied to a series of classical flow regimes.

Turbulent Reynolds stress and quadrant event activity in wind flow over a coastal foredune

NASA Astrophysics Data System (ADS)

Chapman, Connie A.; Walker, Ian J.; Hesp, Patrick A.; Bauer, Bernard O.; Davidson-Arnott, Robin G. D.

2012-05-01

Recent research on quasi-instantaneous turbulent kinematic Reynolds stresses (RS, - u'w') and decomposed quadrant event activity (e.g., ejections and sweeps) over dunes in fluvial settings and in wind tunnels has shown that turbulent stresses at the toe of a dune often exceed time-averaged, streamwise shear stress (ρ u * 2) estimates. It is believed that semi-coherent turbulent structures are conveyed toward the bed along concave streamlines in this region and that impact of these structures cause fluctuations in local surface stresses that assist in grain entrainment. This has been hypothesized to explain how sand is supplied to the windward slope through a region of flow stagnation. Toward the crest, surface stress increases and becomes dominated by streamwise accelerations resulting from streamline compression and convexity that suppress vertical motions. High-frequency (32 Hz) measurements of turbulent wind flow from 3-D ultrasonic anemometers are analyzed for oblique onshore flow over a vegetated coastal foredune in Prince Edward Island, Canada. Reynolds stress and quadrant activity distributions varied with height (0.60 m and 1.66 m) and location over the dune. In general, quadrant 2 ejection (u' < 0, w' > 0) and quadrant 4 sweep activity (u' > 0, w' < 0) dominated momentum transfer and RS generation over quadrant 1 outward interaction (u' > 0, w' > 0) and quadrant 3 inward interaction (u' < 0, w' < 0) activity. On the lower stoss slope, significant ejection and sweep event activity was most frequent (85 to 92%, ejections plus sweeps), whereas, at the upper crest, significant ejection and sweep activity became less frequent while significant outward and inward interactions increased in frequency (25 to 36%). An 'exuberance effect' (i.e., changing shape of quadrant frequency distribution skewed toward ejection and sweep activity) is observed whereby streamline compression and convexity effects inhibit vertical fluctuations in flow and, thus, reduce the frequency of ejections and sweep activity toward the crest. In separated flow in the lee of the crest, quadrant distributions were more symmetrical as a result of more mixed, multi-directional flow. These trends in turbulent event distributions and Reynolds stress have implications for sediment transport dynamics across the dune and may help to explain sand transport potential and dune maintenance. For example, areas with a high frequency of ejection and sweep activity may have higher rates of sediment entrainment and transport, whereas areas with lower ejection and sweep activity and an increase in outward and inward interactions, which contribute negatively to Reynolds stress generation, may experience a greater potential for deposition. Further research on associations between quadrant event activity and coincident sand transport is required to confirm this hypothesis and the resultant significance of the flow exuberance effect in aeolian dune morphodynamics.

Modeling the Effect of Wetlands, Flooding, and Irrigation on River Flow: Application to the Aral Sea

NASA Technical Reports Server (NTRS)

Ferrari, Michael R.; Miller, James R.; Russell, Gary L.

1999-01-01

As the world's population continues to increase, additional stress is placed on water resources. This stress, coupled with future uncertainties regarding climate change, makes arid and semi-arid regions particularly vulnerable. One example is the Aral Sea where the freshwater inflow, which is dominated by snowmelt runoff, has decreased significantly since the expansion of intensive irrigation in the 1960s. The purpose of this paper is to use a river routing scheme from a global climate model to examine the flow of the Amu Dar'ya River into the Aral Sea. The river routing scheme is modified to include groundwater flow, flooding, and evaporative losses in the river's wetlands and floodplain, and anthropogenic withdrawals for irrigation. A set of scenarios is designed to test the sensitivity of river flow to the inclusion of these modifications into the river routing scheme. When riverine wetlands and floodplains are present, the river flow is reduced significantly and is similar to the observed flow. In addition the model results show that it is essential to incorporate human diversions to accurately represent the inflow to the Aral Sea, and they also indicate potential management strategies that might be appropriate to maintain a balance between inflow to the Sea and upstream diversions for irrigation.

Modeling the effect of wetlands, flooding, and irrigation on river flow: Application to the Aral Sea

NASA Astrophysics Data System (ADS)

Ferrari, Michael R.; Miller, James R.; Russell, Gary L.

1999-06-01

As the world's population continues to increase, additional stress is placed on water resources. This stress, coupled with future uncertainties regarding climate change, makes arid and semiarid regions particularly vulnerable. One example is the Aral Sea where the freshwater inflow, which is dominated by snowmelt runoff, has decreased significantly since the expansion of intensive irrigation in the 1960s. The purpose of this paper is to use a river routing scheme from a global climate model to examine the flow of the Amu Dar'ya River into the Aral Sea. The river routing scheme is modified to include groundwater flow, flooding, and evaporative losses in the river's wetlands and floodplain and anthropogenic withdrawals for irrigation. A set of scenarios is designed to test the sensitivity of river flow to the inclusion of these modifications into the river routing scheme. When riverine wetlands and floodplains are present, the river flow is reduced significantly and is similar to the observed flow. In addition, the model results show that it is essential to incorporate human diversions to represent accurately the inflow to the Aral Sea, and they also indicate potential management strategies that might be appropriate to maintain a balance between inflow to the sea and upstream diversions for irrigation.

Effects of upper mantle heterogeneities on the lithospheric stress field and dynamic topography

NASA Astrophysics Data System (ADS)

Osei Tutu, Anthony; Steinberger, Bernhard; Sobolev, Stephan V.; Rogozhina, Irina; Popov, Anton A.

2018-05-01

The orientation and tectonic regime of the observed crustal/lithospheric stress field contribute to our knowledge of different deformation processes occurring within the Earth's crust and lithosphere. In this study, we analyze the influence of the thermal and density structure of the upper mantle on the lithospheric stress field and topography. We use a 3-D lithosphere-asthenosphere numerical model with power-law rheology, coupled to a spectral mantle flow code at 300 km depth. Our results are validated against the World Stress Map 2016 (WSM2016) and the observation-based residual topography. We derive the upper mantle thermal structure from either a heat flow model combined with a seafloor age model (TM1) or a global S-wave velocity model (TM2). We show that lateral density heterogeneities in the upper 300 km have a limited influence on the modeled horizontal stress field as opposed to the resulting dynamic topography that appears more sensitive to such heterogeneities. The modeled stress field directions, using only the mantle heterogeneities below 300 km, are not perturbed much when the effects of lithosphere and crust above 300 km are added. In contrast, modeled stress magnitudes and dynamic topography are to a greater extent controlled by the upper mantle density structure. After correction for the chemical depletion of continents, the TM2 model leads to a much better fit with the observed residual topography giving a good correlation of 0.51 in continents, but this correction leads to no significant improvement of the fit between the WSM2016 and the resulting lithosphere stresses. In continental regions with abundant heat flow data, TM1 results in relatively small angular misfits. For example, in western Europe the misfit between the modeled and observation-based stress is 18.3°. Our findings emphasize that the relative contributions coming from shallow and deep mantle dynamic forces are quite different for the lithospheric stress field and dynamic topography.

Mechanical Limits to Size in Wave-Swept Organisms.

DTIC Science & Technology

1983-11-10

complanata, the probability of destruction and the size- specific increase in the risk of destruction are both substantial. It is conjectured that the...barnacle, Semibalanus cariosus) the size-specific increment in the risk of destruction is small and the size limits imposed on these organisms are...constructed here provides an experimental approach to examining many potential effects of environmental stress caused by flowing water. For example, these

Permeability, Fracture Clusters, and Stress State:Implications for Mine-based Studies of EcoHydrology

NASA Astrophysics Data System (ADS)

Earnest, E. J.; Boutt, D. F.; Murdoch, L.; Hisz, D. B.; Ebenhack, J.; Kieft, T. L.; Onstott, T. C.; Wang, H. F.

2011-12-01

Mine-based ecohydrology studies provide unique access to deep flow systems at multiple crustal depths. Mass and energy transfer in such deep flow systems is typically dominated by localized flow through discrete features such as fractures and faults, of which only a small percentage contribute to both local and regional flow systems. Predicting which fractures are contributing to flow and transport in these networks has proven extremely difficult. Researchers working at deeper crustal levels (Barton et al., 1995) have successfully predicted fracture network permeability using relationships between fracture aperture (i.e. transmissivity) and in-situ stress. Observations suggest that compared to porous media, fractured rocks have flow systems that operate across large spatial scales and may contain clusters that are hydraulically isolated. . This point is important as these flow systems can house fluids and microbes in isolated clusters and are minimally impacted by the presence of a mine. One example of this is the the former Homestake gold mine in the northern Black Hills, South Dakota, which is being considered as a location for an underground science laboratory. Mine workings cover several km2 in plan and extend to a depth 2.4 km. The area is dominantly Proterozoic metamorphic rocks, forming regional-scale folds with plunge axes oriented ~40o to the SSE. Prior analysis of the hydrogeology of the area indicates that permeability is strongly dependent on effective stress; an increase in permeability with decreasing depth appears to be an important factor controlling the development of a shallow ground water flow systems. In this contribution we examine a set of factors contributing to permeability distribution at the site with a specific focus on: 1) refining permeability-depth models for fractured rock to include the influence of both normal and shear fracture deformation on permeability-depth trends, 2) promote the development and testing of a stress-path fracture permeability hypothesis to examine space-time fracture permeability evolution at various depths, and 3) evaluate factors necessary to create and sustain isolated fracture clusters that could be targets for studies of ecohydrology. Preliminary field work in fractured rocks of Eastern Massachusetts suggest that the stress-path hypothesis, in which fracture permeability undergoes spatial and temporal changes due to erosion and rotatation of the in situ stress field, can be used to explain depth-dependent permeability trends, and is particularly significant for flow systems at depths significant for deep ecohydrology studies.

Direct method of design and stress analysis of rotating disks with temperature gradient

NASA Technical Reports Server (NTRS)

Manson, S S

1950-01-01

A method is presented for the determination of the contour of disks, typified by those of aircraft gas turbines, to incorporate arbitrary elastic-stress distributions resulting from either centrifugal or combined centrifugal and thermal effects. The specified stress may be radial, tangential, or any combination of the two. Use is made of the finite-difference approach in solving the stress equations, the amount of computation necessary in the evolution of a design being greatly reduced by the judicious selection of point stations by the aid of a design chart. Use of the charts and of a preselected schedule of point stations is also applied to the direct problem of finding the elastic and plastic stress distribution in disks of a given design, thereby effecting a great reduction in the amount of calculation. Illustrative examples are presented to show computational procedures in the determination of a new design and in analyzing an existing design for elastic stress and for stresses resulting from plastic flow.

Direct Numerical Simulation of Fingering Instabilities in Coating Flows

NASA Astrophysics Data System (ADS)

Eres, Murat H.; Schwartz, Leonard W.

1998-11-01

We consider stability and finger formation in free surface flows. Gravity driven downhill drainage and temperature gradient driven climbing flows are two examples of such problems. The former situation occurs when a mound of viscous liquid on a vertical wall is allowed to flow. Constant surface shear stress due to temperature gradients (Marangoni stress) can initiate the latter problem. The evolution equations are derived using the lubrication approximation. We also include the effects of finite-contact angles in the evolution equations using a disjoining pressure model. Evolution equations for both problems are solved using an efficient alternating-direction-implicit method. For both problems a one-dimensional base state is established, that is steady in a moving reference frame. This base state is unstable to transverse perturbations. The transverse wavenumbers for the most rapidly growing modes are found through direct numerical solution of the nonlinear evolution equations, and are compared with published experimental results. For a range of finite equilibrium contact angles, the fingers can grow without limit leading to semi-finite steady fingers in a moving coordinate system. A computer generated movie of the nonlinear simulation results, for several sets of input parameters, will be shown.

Impinging Jets and the Erodibility of Cohesive Sediment

NASA Astrophysics Data System (ADS)

Karamigolbaghi, M.; Bennett, S. J.; Ghaneeizad, S. M.; Atkinson, J. F.

2016-12-01

Defining the erodibility of cohesive sediment remains a critical challenge in Earth surface systems. The primary geomorphic law used in such applications relates erosion rate to an erodibility coefficient and an excess shear stress term. To assess erodibility, an inverse modeling approach can be adopted, wherein a known stress is applied to the cohesive sediment, and the erodibility parameters can be deduced through observation of erosion as a function of time. An impinging jet, as used in the jet erosion test, would appear to be an ideal flow (stress) source for erosion assessment. Recent work, however, has demonstrated that jet hydrodynamics can depart significantly from ideal flow conditions when employed for in situ erosion assessment. Here we will review jet theory and the use of jets for assessing the erodibility of cohesive sediment. Our results show that (1) flow confinement and the generation of secondary circulation can significantly change bed shear stress near and downstream of impingement, (2) the evolving scour hole shape, as conditioned by material characteristics and the erosion process, can significantly alter jet hydrodynamics and bed shear stress magnitudes and distributions near and downstream of impingement, and (3) incidental variations in material characteristics in carefully-executed, long-lived experiments can produce markedly different scour hole shapes and derived erodibility indices. Examples from experimental, numerical, and field observations will be used to illustrate these hydrodynamic and material effects on observed and predicted erosion rates. Because such effects are difficult to anticipate, the uncertainty of in situ cohesive sediment assessments using impinging jets can be quite large.

The wall traction induced by flowing red blood cells in model microvessels and its potential mechanotransduction

NASA Astrophysics Data System (ADS)

Freund, Jonathan; Vermot, Julien

2013-11-01

There is evidence in early embryonic development, even well before advective oxygen transport is important, that the presence of red bloods cells per se trigger essential steps of normal vascular development. For example, showed that sequestration of blood cells early in the development of a mouse, such that the hematocrit is reduced, suppresses normal vascular network development. Vascular development also provides a model for remodeling and angiogenesis. We consider the transient stresses associated with blood cells flowing in model microvessels of comparable diameter to those at early stages of development (6 μm to 12 μm). A detailed simulation tool is used to show that passing blood cells present a significant fluctuating traction signature on the vessel wall, well above the mean stresses. This is particularly pronounced for slow flows (<= 50 μm/s) or small diameters (<= 7 μm), for which root-mean-square wall traction fluctuations can exceed their mean. These events potentially present mechanotranduction triggers that direct development or remodeling. Attenuation of such fluctuating tractions by a viscoelastic endothelial glycocalyx layer is also considered. NSF supported.

Experience with turbulence interaction and turbulence-chemistry models at Fluent Inc.

NASA Technical Reports Server (NTRS)

Choudhury, D.; Kim, S. E.; Tselepidakis, D. P.; Missaghi, M.

1995-01-01

This viewgraph presentation discusses (1) turbulence modeling: challenges in turbulence modeling, desirable attributes of turbulence models, turbulence models in FLUENT, and examples using FLUENT; and (2) combustion modeling: turbulence-chemistry interaction and FLUENT equilibrium model. As of now, three turbulence models are provided: the conventional k-epsilon model, the renormalization group model, and the Reynolds-stress model. The renormalization group k-epsilon model has broadened the range of applicability of two-equation turbulence models. The Reynolds-stress model has proved useful for strongly anisotropic flows such as those encountered in cyclones, swirlers, and combustors. Issues remain, such as near-wall closure, with all classes of models.

Steady inviscid transonic flows over planar airfoils: A search for a simplified procedure

NASA Technical Reports Server (NTRS)

Magnus, R.; Yoshihara, H.

1973-01-01

A finite difference procedure based upon a system of unsteady equations in proper conservation form with either exact or small disturbance steady terms is used to calculate the steady flows over several classes of airfoils. The airfoil condition is fulfilled on a slab whose upstream extremity is a semi-circle overlaying the airfoil leading edge circle. The limitations of the small disturbance equations are demonstrated in an extreme example of a blunt-nosed, aft-cambered airfoil. The necessity of using the equations in proper conservation form to capture the shock properly is stressed. Ability of the steady relaxation procedures to capture the shock is briefly examined.

Optimising Cell Aggregate Expansion in a Perfused Hollow Fibre Bioreactor via Mathematical Modelling

PubMed Central

Chapman, Lloyd A. C.; Shipley, Rebecca J.; Whiteley, Jonathan P.; Ellis, Marianne J.; Byrne, Helen M.; Waters, Sarah L.

2014-01-01

The need for efficient and controlled expansion of cell populations is paramount in tissue engineering. Hollow fibre bioreactors (HFBs) have the potential to meet this need, but only with improved understanding of how operating conditions and cell seeding strategy affect cell proliferation in the bioreactor. This study is designed to assess the effects of two key operating parameters (the flow rate of culture medium into the fibre lumen and the fluid pressure imposed at the lumen outlet), together with the cell seeding distribution, on cell population growth in a single-fibre HFB. This is achieved using mathematical modelling and numerical methods to simulate the growth of cell aggregates along the outer surface of the fibre in response to the local oxygen concentration and fluid shear stress. The oxygen delivery to the cell aggregates and the fluid shear stress increase as the flow rate and pressure imposed at the lumen outlet are increased. Although the increased oxygen delivery promotes growth, the higher fluid shear stress can lead to cell death. For a given cell type and initial aggregate distribution, the operating parameters that give the most rapid overall growth can be identified from simulations. For example, when aggregates of rat cardiomyocytes that can tolerate shear stresses of up to are evenly distributed along the fibre, the inlet flow rate and outlet pressure that maximise the overall growth rate are predicted to be in the ranges to (equivalent to to ) and to (or 15.6 psi to 15.7 psi) respectively. The combined effects of the seeding distribution and flow on the growth are also investigated and the optimal conditions for growth found to depend on the shear tolerance and oxygen demands of the cells. PMID:25157635

Large-eddy simulations with wall models

NASA Technical Reports Server (NTRS)

Cabot, W.

1995-01-01

The near-wall viscous and buffer regions of wall-bounded flows generally require a large expenditure of computational resources to be resolved adequately, even in large-eddy simulation (LES). Often as much as 50% of the grid points in a computational domain are devoted to these regions. The dense grids that this implies also generally require small time steps for numerical stability and/or accuracy. It is commonly assumed that the inner wall layers are near equilibrium, so that the standard logarithmic law can be applied as the boundary condition for the wall stress well away from the wall, for example, in the logarithmic region, obviating the need to expend large amounts of grid points and computational time in this region. This approach is commonly employed in LES of planetary boundary layers, and it has also been used for some simple engineering flows. In order to calculate accurately a wall-bounded flow with coarse wall resolution, one requires the wall stress as a boundary condition. The goal of this work is to determine the extent to which equilibrium and boundary layer assumptions are valid in the near-wall regions, to develop models for the inner layer based on such assumptions, and to test these modeling ideas in some relatively simple flows with different pressure gradients, such as channel flow and flow over a backward-facing step. Ultimately, models that perform adequately in these situations will be applied to more complex flow configurations, such as an airfoil.

Impact of lithosphere rheology on the dynamic topography

NASA Astrophysics Data System (ADS)

Burov, Evgueni; Gerya, Taras; Koptev, Alexander

2014-05-01

Dynamic topography is a key observable signature of the Earth's and planetary (e.g. Venus) mantle dynamics. In general view, it reflects complex mantle flow patterns, and hence is supposed to correlate at different extent with seismic tomography, SKS fast orientations, geodetic velocity fields and geoid anomalies. However, identification of dynamic topography had no systematic success, specifically in the Earth's continents. Here we argue that lithosphere rheology, in particular, rheological stratification of continents, results in modulation of dynamic topography, converting commonly expected long-wavelength/small amplitude undulations into short-wavelength surface undulations with wide amplitude spectrum, superimposed onto "tectonic" topography. These ideas are explored in 3D using unprecedentedly high resolution numerical experiments (grid step size 2-3 km for 1500x1500x600 km computational area) incorporating realistic rheologically stratified lithosphere. Such high resolution is actually needed to resolve small-scale crustal faulting and inter-layer coupling/uncoupling that shape surface topography. The results reveal strikingly discordant, counterintuitive features of 3D dynamic topography, going far beyond the inferences from previous models. In particular, even weak anisotropic tectonic stress field results both in large-scale small-amplitude dynamic topography and in strongly anisotropic short-wavelength (at least in one direction) dynamic topography with wide amplitude range (from 100 to 2000-3000 m), including basins and ranges and large-scale linear normal and strike-slip faults. Even very slightly pre-stressed strong lithosphere yields and localizes deformation much easier , than un-prestressed one, in response to plume impact and mantle flow. The results shed new light on the importance of lithosphere rheology and active role of lithosphere in mantle-lithosphere interactions as well as on the role of mantle flow and far-field stresses in tectonic-scale deformation. We show, for example, that crustal fault patterns initiated by plume impact are rapidly re-organized in sub-linear rifts and spreading centers, which orientation is largely dictated (e.g., perpendicular to) by the direction of the tectonic far-field stress field, as well as the plume-head material soon starts to flow along the sub-linear rifted shear zones in crustal and mantle lithosphere further amplifying their development. The final surface deformation and mantle flow patterns rapidly loose the initial axisymmetric character and take elongated sub-linear shapes whereas brittle deformation at surface is amplified and stabilized by coherent flow of mantle/plume-head material from below. These "tectonically" looking dynamic topography patterns are quite different from those expected from conventional models as well as from those directly observed, for example, on Venus where plume-lithosphere interactions produce only axisymmetric coronae domal-shaped features with radiating extensional rifts, suggesting that the Venusian lithosphere is rheologically too weak , and its crust is too thin, to produce any significant impact on the dynamic topography.

Expectations in the Wall Region of a Large-Eddy Simulation

NASA Astrophysics Data System (ADS)

Spalart, Philippe R.; Strelets, Mikhail Kh.; Travin, Andrey

The expectations fall into two categories. The first relates to the method and how general it should be, how applicable to unstructured grids in complex three-dimensional geometries and very high Reynolds numbers, even if the exercise uses a structured grid in a two-dimensional flow at moderate Reynolds number. The view-point is that there should be a known path from the research activity to the creation of a machine or the prediction of weather. If not, the gap in this path takes on a high priority and the work is labeled as preliminary. An example of such a litmus test is whether the grid design requires knowledge of the direction of the skin friction. The second category relates to the fidelity of the description of the turbulence which can be assembled. As an example, the shear stress in a wall-bounded LES is calculated quite well as the sum of a viscous stress, a "modeled" Reynolds stress, and a "resolved" Reynolds stress. However, the same has not been achieved for the other Reynolds stresses, unless the grid is such that Quasi-Direct Numerical Simulation is taking place. Higher-order quantities are even more troublesome. We also discuss a remedy to Log-Layer Mismatch called "Energized Wall-Modeled LES" which is most simple, cost-free, and compatible with grids that are useable in practice. The added term provides visible extra activity, and improves all the Reynolds stresses in addition to the mean velocity.

Creep of Ni(3)Al in the temperature regime of anomalous flow behavior

NASA Astrophysics Data System (ADS)

Uchic, Michael David

Much attention has been paid to understanding the dynamics of dislocation motion and substructure formation in Ni3Al in the anomalous flow regime. However, most of the experimental work that has been performed in the lowest temperatures of the anomalous flow regime has been under constant-strain-rate conditions. An alternative and perhaps more fundamental way to probe the plastic behavior of materials is a monotonic creep test, in which the stress and temperature are held constant while the time-dependent strain is measured. The aim of this study is to use constant-stress experiments to further explore the plastic flow anomaly in L12 alloys at low temperatures. Tension creep experiments have been carried out on <123> oriented single crystals of Ni75Al24Ta1 at temperatures between 293 and 473 K. We have observed primary creep leading to exhaustion at all temperatures and stresses, with creep rates declining faster than predicted by the logarithmic creep law. The total strain and creep strain have an anomalous dependence on temperature, which is consistent with the flow stress anomaly. We have also observed other unusual behavior in our creep experiments; for example, the reinitiation of plastic flow at low temperatures after a modest increment in applied stress shows a sigmoidal response, i.e., there is a significant time delay before the plastic strain rate accelerates to a maximum value. We also examined the ability to reinitiate plastic flow in samples that have been crept to exhaustion by simply lowering the test temperature. In addition, we have also performed conventional constant-displacement-rate experiments in the same temperature range. From these experiments, we have discovered that unlike most metals, Ni3Al displays a negative dependence of the work hardening rate (WHR) with increasing strain rate. For tests at intermediate temperatures (373 and 423 K), the WHRs of crystals tested at moderately high strain rates (10-2 s-1) are half the WHRs of crystals tested at conventional strain rates (10 -5 s-1), and this anomalous dependence has also been shown to be reversible with changes in strain rate. The implications of all results are discussed in light of our efforts to model plastic deformation in these alloys.

Droplet Deformation in an Extensional Flow: The Role of Surfactant Physical Chemistry

NASA Technical Reports Server (NTRS)

Stebe, Kathleen J.

1996-01-01

Surfactant-induced Marangoni effects strongly alter the stresses exerted along fluid particle interfaces. In low gravity processes, these stresses can dictate the system behavior. The dependence of Marangoni effects on surfactant physical chemistry is not understood, severely impacting our ability to predict and control fluid particle flows. A droplet in an extensional flow allows the controlled study of stretching and deforming interfaces. The deformations of the drop allow both Marangoni stresses, which resist tangential shear, and Marangoni elasticities, which resist surface dilatation, to develop. This flow presents an ideal model system for studying these effects. Prior surfactant-related work in this flow considered a linear dependence of the surface tension on the surface concentration, valid only at dilute surface concentrations, or a non-linear framework at concentrations sufficiently dilute that the linear approximation was valid. The linear framework becomes inadequate for several reasons. The finite dimensions of surfactant molecules must be taken into account with a model that includes surfaces saturation. Nonideal interactions between adsorbed surfactant molecules alter the partitioning of surfactant between the bulk and the interface, the dynamics of surfactant adsorptive/desorptive exchange, and the sensitivity of the surface tension to adsorbed surfactant. For example, cohesion between hydrocarbon chains favors strong adsorption. Cohesion also slows the rate of desorption from interfaces, and decreases the sensitivity of the surface tension to adsorbed surfactant. Strong cohesive interactions result in first order surface phase changes with a plateau in the surface tension vs surface concentration. Within this surface concentration range, the surface tension is decoupled from surface concentration gradients. We are engaged in the study of the role of surfactant physical chemistry in determining the Marangoni stresses on a drop in an extensional flow in a numerical and experimental program. Using surfactants whose dynamics and equilibrium behavior have been characterized in our laboratory, drop deformation will be studied in ground-based experiment. In an accompanying numerical study, predictive drop deformations will be determined based on the isotherm and equation of state determined in our laboratory. This work will improve our abilities to predict and control all fluid particle flows.

Dynamical Evaluation of Ocean Models using the Gulf Stream as an Example

DTIC Science & Technology

2010-01-01

transport for the Atlantic meridional overturning circulation (AMOC) as the 3 nonlinear solutions discussed in Section 2. The model boundary is...Hellerman and Rosenstein (1983) wind stress climatology and the northward upper ocean flow (14 Sv) of the Atlantic meridional overturning circulation ... overturning circulation (AMOC) streamfunction with a 5 Sv contour interval from (a) 1/12° Atlantic MICOM, (b) 1/12° Atlantic HYCOM, and (c) 1/12

Annual Technical Report, Materials Research Laboratory, 1 July 1982 - 30 June 1983.

DTIC Science & Technology

1983-06-30

array of 10 determine the gnajlerial properties to strain rates infra-red radiation detectors , each of which measures greater than 10 s’. temperature...linear array of detectors which will allow us a closer num a drop in temperature raises the flow stress, look at the temperature profile, especially...Hartley, M.S. example, experimental evidence for quantum-me- Thesis, June, 1983. chanical tunneling effects on the viscoelastic relaxa- tion in poly

An Approximate Axisymmetric Viscous Shock Layer Aeroheating Method for Three-Dimensional Bodies

NASA Technical Reports Server (NTRS)

Brykina, Irina G.; Scott, Carl D.

1998-01-01

A technique is implemented for computing hypersonic aeroheating, shear stress, and other flow properties on the windward side of a three-dimensional (3D) blunt body. The technique uses a 2D/axisymmetric flow solver modified by scale factors for a, corresponding equivalent axisymmetric body. Examples are given in which a 2D solver is used to calculate the flow at selected meridional planes on elliptic paraboloids in reentry flight. The report describes the equations and the codes used to convert the body surface parameters into input used to scale the 2D viscous shock layer equations in the axisymmetric viscous shock layer code. Very good agreement is obtained with solutions to finite rate chemistry 3D thin viscous shock layer equations for a finite rate catalytic body.

Modeling the evolution of channel shape: Balancing computational efficiency with hydraulic fidelity

USGS Publications Warehouse

Wobus, C.W.; Kean, J.W.; Tucker, G.E.; Anderson, R. Scott

2008-01-01

The cross-sectional shape of a natural river channel controls the capacity of the system to carry water off a landscape, to convey sediment derived from hillslopes, and to erode its bed and banks. Numerical models that describe the response of a landscape to changes in climate or tectonics therefore require formulations that can accommodate evolution of channel cross-sectional geometry. However, fully two-dimensional (2-D) flow models are too computationally expensive to implement in large-scale landscape evolution models, while available simple empirical relationships between width and discharge do not adequately capture the dynamics of channel adjustment. We have developed a simplified 2-D numerical model of channel evolution in a cohesive, detachment-limited substrate subject to steady, unidirectional flow. Erosion is assumed to be proportional to boundary shear stress, which is calculated using an approximation of the flow field in which log-velocity profiles are assumed to apply along vectors that are perpendicular to the local channel bed. Model predictions of the velocity structure, peak boundary shear stress, and equilibrium channel shape compare well with predictions of a more sophisticated but more computationally demanding ray-isovel model. For example, the mean velocities computed by the two models are consistent to within ???3%, and the predicted peak shear stress is consistent to within ???7%. Furthermore, the shear stress distributions predicted by our model compare favorably with available laboratory measurements for prescribed channel shapes. A modification to our simplified code in which the flow includes a high-velocity core allows the model to be extended to estimate shear stress distributions in channels with large width-to-depth ratios. Our model is efficient enough to incorporate into large-scale landscape evolution codes and can be used to examine how channels adjust both cross-sectional shape and slope in response to tectonic and climatic forcing. Copyright 2008 by the American Geophysical Union.

NMR imaging and hydrodynamic analysis of neutrally buoyant non-Newtonian slurry flows

NASA Astrophysics Data System (ADS)

Bouillard, J. X.; Sinton, S. W.

The flow of solids loaded suspension in cylindrical pipes has been the object of intense experimental and theoretical investigations in recent years. These types of flows are of great interest in chemical engineering because of their important use in many industrial manufacturing processes. Such flows are for example encountered in the manufacture of solid-rocket propellants, advanced ceramics, reinforced polymer composites, in heterogeneous catalytic reactors, and in the pipeline transport of liquid-solids suspensions. In most cases, the suspension microstructure and the degree of solids dispersion greatly affect the final performance of the manufactured product. For example, solid propellant pellets need to be extremely-well dispersed in gel matrices for use as rocket engine solid fuels. The homogeneity of pellet dispersion is critical to allow good uniformity of the burn rate, which in turn affects the final mechanical performance of the engine. Today's manufacturing of such fuels uses continuous flow processes rather than batch processes. Unfortunately, the hydrodynamics of such flow processes is poorly understood and is difficult to assess because it requires the simultaneous measurements of liquid/solids phase velocities and volume fractions. Due to the recent development in pulsed Fourier Transform NMR imaging, NMR imaging is now becoming a powerful technique for the non intrusive investigation of multi-phase flows. This paper reports and exposes a state-of-the-art experimental and theoretical methodology that can be used to study such flows. The hydrodynamic model developed for this study is a two-phase flow shear thinning model with standard constitutive fluid/solids interphase drag and solids compaction stresses. this model shows good agreement with experimental data and the limitations of this model are discussed.

[Aspects of vascular physiology in clinical and vascular surgical practice: basic principles of vascular mechanics].

PubMed

Nocke, H; Meyer, F; Lessmann, V

2014-10-01

To be able to evaluate properly a vascular problem, basic concepts of vascular physiology need to be considered, as they have been taught in physiology for a long time. This article deals with selected definitions and laws of passive vascular mechanics, subdivided into parameters of vascular filling and parameters of vascular flow. PARAMETERS OF VASCULAR FILLING: During vascular filling the transmural pressure distends the vascular wall until it is balanced by the wall tension. The extent of this distension up to the point of balance depends on the elasticity of the wall. Transmural pressure, wall tension and elasticity are defined, and their respective importance is described by clinical examples, e.g. aneurysm and varix. PARAMETERS OF VASCULAR FLOW: The vascular flow can be divided into stationary and pulsating components. Both components are relevant for the bloodstream. Since the blood flow is directed in the circuit, it can be understood in first approximation as stationary ("direct current").The direct current model uses only the average values of the pulsating variables. The great advantage of the direct current model is that it can be described with simple laws, which are not valid without reservation, but often allow a first theoretical approach to a vascular problem: Ohm's law, driving pressure, flow resistance, Hagen-Poiseuille law, wall shear stress, law of continuity, Bernoulli's equation and Reynold's number are described and associated with clinical examples.The heart is a pressure-suction pump and produces a pulsating flow, the pulse. The pulse runs with pulse wave velocity, which is much larger than the blood flow velocity, through the arterial vascular system. During propagation, the pulse has to overcome the wave resistance (impedance). Wherever the wave resistance changes, e.g., at vascular bifurcations and in the periphery, it comes to reflections. The incident (forward) and reflected (backward) waves are superimposed to yield the resulting pulse wave. This pulse wave allows one to distinguish pressure and flow pulse by measurement. Both are described separately, and their respective clinical meaning is illustrated by appropriate examples, e.g., arterial stiffness and pre-/postocclusive high/low resistance flow, respectively. Georg Thieme Verlag KG Stuttgart · New York.

Interfacial mechanisms for stability of surfactant-laden films

PubMed Central

Chai, Chew; Àlvarez-Valenzuela, Marco A.; Tajuelo, Javier; Fuller, Gerald G.

2017-01-01

Thin liquid films are central to everyday life. They are ubiquitous in modern technology (pharmaceuticals, coatings), consumer products (foams, emulsions) and also serve vital biological functions (tear film of the eye, pulmonary surfactants in the lung). A common feature in all these examples is the presence of surface-active molecules at the air-liquid interface. Though they form only molecular-thin layers, these surfactants produce complex surface stresses on the free surface, which have important consequences for the dynamics and stability of the underlying thin liquid film. Here we conduct simple thinning experiments to explore the fundamental mechanisms that allow the surfactant molecules to slow the gravity-driven drainage of the underlying film. We present a simple model that works for both soluble and insoluble surfactant systems in the limit of negligible adsorption-desorption dynamics. We show that surfactants with finite surface rheology influence bulk flow through viscoelastic interfacial stresses, while surfactants with inviscid surfaces achieve stability through opposing surface-tension induced Marangoni flows. PMID:28520734

Dynamics of yield-stress droplets: Morphology of impact craters

NASA Astrophysics Data System (ADS)

Neufeld, Jerome; Sohr, David; Ferrari, Leo; Dalziel, Stuart

2017-11-01

Yield strength can play an important role for the dynamics of droplets impacting on surfaces, whether at the industrial or planetary scale, and can capture a zoo of impact crater morphologies, from simple parabolic craters, to more complex forms with forms with, for example, multiple rings, central peaks. Here we show that the morphology of planetary impact craters can be reproduced in the laboratory using carbopol, a transparent yield-stress fluid, as both impactor and bulk fluid. Using high-speed video photography, we characterise the universal, transient initial excavation stage of impact and show the dependence of the subsequent relaxation to final crater morphology on impactor size, impact speed and yield stress. To further interrogate our laboratory impacts, we dye our impactor to map its final distribution and use particle tracking to determine the flow fields during impact and the maximal extent of the yield surface. We characterise the flow-fields induced during impact, and the maximal extent of the yield surface, by tracking particles within the bulk fluid and map the distribution of impactor and bulk by tracing the final distribution of dyed impactor. The results of laboratory impact droplets are used to infer the properties of planetary impactors, and aid in inter.

Effect of an eigenstrain on slow viscous flow of compressible fluid films

DOE Office of Scientific and Technical Information (OSTI.GOV)

Murray, P.E.

We present a general formulation of the mechanics of slow viscous flow of slightly compressible fluid films in the presence of an eigenstrain. An eigenstrain represents a constrained volume change due to temperature, concentration of a dissolved species, or a chemical transformation. A silicon dioxide film grown on a silicon surface is an example of a viscous fluid film that is affected by a constrained volume change. We obtain a general expression for pressure in a fluid film produced by a surface chemical reaction accompanied by a volume change. This result is used to study the effect of an eigenstrainmore » on viscous stress relaxation in fluid films.« less

The Topographic Design of River Channels for Form-Process Linkages.

PubMed

Brown, Rocko A; Pasternack, Gregory B; Lin, Tin

2016-04-01

Scientists and engineers design river topography for a wide variety of uses, such as experimentation, site remediation, dam mitigation, flood management, and river restoration. A recent advancement has been the notion of topographical design to yield specific fluvial mechanisms in conjunction with natural or environmental flow releases. For example, the flow convergence routing mechanism, whereby shear stress and spatially convergent flow migrate or jump from the topographic high (riffle) to the low point (pool) from low to high discharge, is thought to be a key process able to maintain undular relief in gravel bedded rivers. This paper develops an approach to creating riffle-pool topography with a form-process linkage to the flow convergence routing mechanism using an adjustable, quasi equilibrium synthetic channel model. The link from form to process is made through conceptualizing form-process relationships for riffle-pool couplets into geomorphic covariance structures (GCSs) that are then quantitatively embedded in a synthetic channel model. Herein, GCSs were used to parameterize a geometric model to create five straight, synthetic river channels with varying combinations of bed and width undulations. Shear stress and flow direction predictions from 2D hydrodynamic modeling were used to determine if scenarios recreated aspects of the flow convergence routing mechanism. Results show that the creation of riffle-pool couplets that experience flow convergence in straight channels requires GCSs with covarying bed and width undulations in their topography as supported in the literature. This shows that GCSs are a useful way to translate conceptualizations of form-process linkages into quantitative models of channel form.

Ultrasonic velocity profiling rheometry based on a widened circular Couette flow

NASA Astrophysics Data System (ADS)

Shiratori, Takahisa; Tasaka, Yuji; Oishi, Yoshihiko; Murai, Yuichi

2015-08-01

We propose a new rheometry for characterizing the rheological properties of fluids. The technique produces flow curves, which represent the relationship between the fluid shear rate and shear stress. Flow curves are obtained by measuring the circumferential velocity distribution of tested fluids in a circular Couette system, using an ultrasonic velocity profiling technique. By adopting a widened gap of concentric cylinders, a designed range of the shear rate is obtained so that velocity profile measurement along a single line directly acquires flow curves. To reduce the effect of ultrasonic noise on resultant flow curves, several fitting functions and variable transforms are examined to best approximate the velocity profile without introducing a priori rheological models. Silicone oil, polyacrylamide solution, and yogurt were used to evaluate the applicability of this technique. These substances are purposely targeted as examples of Newtonian fluids, shear thinning fluids, and opaque fluids with unknown rheological properties, respectively. We find that fourth-order Chebyshev polynomials provide the most accurate representation of flow curves in the context of model-free rheometry enabled by ultrasonic velocity profiling.

Glenn-HT: The NASA Glenn Research Center General Multi-Block Navier-Stokes Heat Transfer Code

NASA Technical Reports Server (NTRS)

Gaugler, Raymond E.; Lee, Chi-Miag (Technical Monitor)

2001-01-01

For the last several years, Glenn-HT, a three-dimensional (3D) Computational Fluid Dynamics (CFD) computer code for the analysis of gas turbine flow and convective heat transfer has been evolving at the NASA Glenn Research Center. The code is unique in the ability to give a highly detailed representation of the flow field very close to solid surfaces in order to get accurate representation of fluid heat transfer and viscous shear stresses. The code has been validated and used extensively for both internal cooling passage flow and for hot gas path flows, including detailed film cooling calculations and complex tip clearance gap flow and heat transfer. In its current form, this code has a multiblock grid capability and has been validated for a number of turbine configurations. The code has been developed and used primarily as a research tool, but it can be useful for detailed design analysis. In this paper, the code is described and examples of its validation and use for complex flow calculations are presented, emphasizing the applicability to turbomachinery for space launch vehicle propulsion systems.

Glenn-HT: The NASA Glenn Research Center General Multi-Block Navier-Stokes Heat Transfer Code

NASA Technical Reports Server (NTRS)

Gaugfer, Raymond E.

2002-01-01

For the last several years, Glenn-HT, a three-dimensional (3D) Computational Fluid Dynamics (CFD) computer code for the analysis of gas turbine flow and convective heat transfer has been evolving at the NASA Glenn Research Center. The code is unique in the ability to give a highly detailed representation of the flow field very close to solid surfaces in order to get accurate representation of fluid heat transfer and viscous shear stresses. The code has been validated and used extensively for both internal cooling passage flow and for hot gas path flows, including detailed film cooling calculations and complex tip clearance gap flow and heat transfer. In its current form, this code has a multiblock grid capability and has been validated for a number of turbine configurations. The code has been developed and used primarily as a research tool, but it can be useful for detailed design analysis. In this presentation, the code is described and examples of its validation and use for complex flow calculations are presented, emphasizing the applicability to turbomachinery.

Glenn-HT: The NASA Glenn Research Center General Multi-Block Navier Stokes Heat Transfer Code

NASA Technical Reports Server (NTRS)

Gaugler, Raymond E.

2002-01-01

For the last several years, Glenn-HT, a three-dimensional (3D) Computational Fluid Dynamics (CFD) computer code for the analysis of gas turbine flow and convective heat transfer has been evolving at the NASA Glenn Research Center. The code is unique in the ability to give a highly detailed representation of the flow field very close to solid surfaces in order to get accurate representation of fluid beat transfer and viscous shear stresses. The code has been validated and used extensively for both internal cooling passage flow and for hot gas path flows, including detailed film cooling calculations and complex tip clearance gap flow and heat transfer. In its current form, this code has a multiblock grid capability and has been validated for a number of turbine configurations. The code has been developed and used primarily as a research tool, but it can be useful for detailed design analysis. In this presentation, the code is described and examples of its validation and use for complex flow calculations are presented, emphasizing the applicability to turbomachinery.

A Hydraulic Stress Measurement System for Deep Borehole Investigations

NASA Astrophysics Data System (ADS)

Ask, Maria; Ask, Daniel; Cornet, Francois; Nilsson, Tommy

2017-04-01

Luleå University of Technology (LTU) is developing and building a wire-line system for hydraulic rock stress measurements, with funding from the Swedish Research Council and Luleå University of Technology. In this project, LTU is collaborating with University of Strasbourg and Geosigma AB. The stress state influences drilling and drillability, as well as rock mass stability and permeability. Therefore, knowledge about the state of in-situ stress (stress magnitudes, and orientations) and its spatial variation with depth is essential for many underground rock engineering projects, for example for underground storage of hazardous material (e.g. nuclear waste, carbon dioxide), deep geothermal exploration, and underground infrastructure (e.g. tunneling, hydropower dams). The system is designed to conduct hydraulic stress testing in slim boreholes. There are three types of test methods: (1) hydraulic fracturing, (2) sleeve fracturing and (3) hydraulic testing of pre-existing fractures. These are robust methods for determining in situ stresses from boreholes. Integration of the three methods allows determination of the three-dimensional stress tensor and its spatial variation with depth in a scientific unambiguously way. The stress system is composed of a downhole and a surface unit. The downhole unit consists of hydraulic fracturing equipment (straddle packers and downhole imaging tool) and their associated data acquisition systems. The testing system is state of the art in several aspects including: (1) Large depth range (3 km), (2) Ability to test three borehole dimensions (N=76 mm, H=96 mm, and P=122 mm), (3) Resistivity imager maps the orientation of tested fracture; (4) Highly stiff and resistive to corrosion downhole testing equipment; and (5) Very detailed control on the injection flow rate and cumulative volume is obtained by a hydraulic injection pump with variable piston rate, and a highly sensitive flow-meter. At EGU General Assembly 2017, we would like to present this new and unique stress measurement system and some initial test results from a 1200 m long borehole in crystalline rock.

Cytoplasmic motion induced by cytoskeleton stretching and its effect on cell mechanics.

PubMed

Zhang, T

2011-09-01

Cytoplasmic motion assumed as a steady state laminar flow induced by cytoskeleton stretching in a cell is determined and its effect on the mechanical behavior of the cell under externally applied forces is demonstrated. Non-Newtonian fluid is assumed for the multiphase cytoplasmic fluid and the analytical velocity field around the macromolecular chain is obtained by solving the reduced nonlinear momentum equation using homotopy technique. The entropy generation by the fluid internal friction is calculated and incorporated into the entropic elasticity based 8-chain constitutive relations. Numerical examples showed strengthening behavior of cells in response to externally applied mechanical stimuli. The spatial distribution of the stresses within a cell under externally applied fluid flow forces were also studied.

Mesoscale simulations of atmospheric flow and tracer transport in Phoenix, Arizona

NASA Astrophysics Data System (ADS)

Wang, Ge; Ostoja-Starzewski, Martin

2006-09-01

Large urban centres located within confining rugged or complex terrain can frequently experience episodes of high concentrations of lower atmospheric pollution. Metropolitan Phoenix, Arizona (United States), is a good example, as the general population is occasionally subjected to high levels of lower atmospheric ozone, carbon monoxide and suspended particulate matter. As a result of dramatic but continuous increase in population, the accompanying environmental stresses and the local atmospheric circulation that dominates the background flow, an accurate simulation of the mesoscale pollutant transport across Phoenix and similar urban areas is becoming increasingly important. This is particularly the case in an airshed, such as that of Phoenix, where the local atmospheric circulation is complicated by the complex terrain of the area.

DEVELOPMENT OF PLASTICITY MODEL USING NON ASSOCIATED FLOW RULE FOR HCP MATERIALS INCLUDING ZIRCONIUM FOR NUCLEAR APPLICATIONS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Michael V. Glazoff; Jeong-Whan Yoon

2013-08-01

In this report (prepared in collaboration with Prof. Jeong Whan Yoon, Deakin University, Melbourne, Australia) a research effort was made to develop a non associated flow rule for zirconium. Since Zr is a hexagonally close packed (hcp) material, it is impossible to describe its plastic response under arbitrary loading conditions with any associated flow rule (e.g. von Mises). As a result of strong tension compression asymmetry of the yield stress and anisotropy, zirconium displays plastic behavior that requires a more sophisticated approach. Consequently, a new general asymmetric yield function has been developed which accommodates mathematically the four directional anisotropies alongmore » 0 degrees, 45 degrees, 90 degrees, and biaxial, under tension and compression. Stress anisotropy has been completely decoupled from the r value by using non associated flow plasticity, where yield function and plastic potential have been treated separately to take care of stress and r value directionalities, respectively. This theoretical development has been verified using Zr alloys at room temperature as an example as these materials have very strong SD (Strength Differential) effect. The proposed yield function reasonably well models the evolution of yield surfaces for a zirconium clock rolled plate during in plane and through thickness compression. It has been found that this function can predict both tension and compression asymmetry mathematically without any numerical tolerance and shows the significant improvement compared to any reported functions. Finally, in the end of the report, a program of further research is outlined aimed at constructing tensorial relationships for the temperature and fluence dependent creep surfaces for Zr, Zircaloy 2, and Zircaloy 4.« less

INCLUDING AORTIC VALVE MORPHOLOGY IN COMPUTATIONAL FLUID DYNAMICS SIMULATIONS: INITIAL FINDINGS AND APPLICATION TO AORTIC COARCTATION

PubMed Central

Wendell, David C.; Samyn, Margaret M.; Cava, Joseph R.; Ellwein, Laura M.; Krolikowski, Mary M.; Gandy, Kimberly L.; Pelech, Andrew N.; Shadden, Shawn C.; LaDisa, John F.

2012-01-01

Computational fluid dynamics (CFD) simulations quantifying thoracic aortic flow patterns have not included disturbances from the aortic valve (AoV). 80% of patients with aortic coarctation (CoA) have a bicuspid aortic valve (BAV) which may cause adverse flow patterns contributing to morbidity. Our objectives were to develop a method to account for the AoV in CFD simulations, and quantify its impact on local hemodynamics. The method developed facilitates segmentation of the AoV, spatiotemporal interpolation of segments, and anatomic positioning of segments at the CFD model inlet. The AoV was included in CFD model examples of a normal (tricuspid AoV) and a post-surgical CoA patient (BAV). Velocity, turbulent kinetic energy (TKE), time-averaged wall shear stress (TAWSS), and oscillatory shear index (OSI) results were compared to equivalent simulations using a plug inlet profile. The plug inlet greatly underestimated TKE for both examples. TAWSS differences extended throughout the thoracic aorta for the CoA BAV, but were limited to the arch for the normal example. OSI differences existed mainly in the ascending aorta for both cases. The impact of AoV can now be included with CFD simulations to identify regions of deleterious hemodynamics thereby advancing simulations of the thoracic aorta one step closer to reality. PMID:22917990

[Endodontics in motion: new concepts, materials and techniques 3. The role of irrigants during root canal treatment].

PubMed

van der Sluis, L W M

2015-10-01

The aims of root canal irrigation are the chemical dissolution or disruption and the mechanical detachment of pulp tissue, dentin debris and smear layer (instrumentation products), microorganisms (planktonic or biofilm) and their products from the root canal wall, their removal out of the root canal system and their chemical dissolution or disruption. Each of the endodontic irrigation systems has its own irrigant flow characteristics, which should fulfill these aims. Without flow (convection), the irrigant would have to be distributed through diffusion. This process is slow and depends on temperature and concentration gradients. On the other hand, convection is a faster and more efficient transport mechanism. During irrigant flow, frictional forces will occur, for example between the irrigant and the root canal wall (wall shear stress). These frictional forces have a mechanical cleaning effect on the root canal wall. These frictional forces are the result of the flow characteristics related to the different irrigation systems.

Mathematical modelling of flow distribution in the human cardiovascular system

NASA Technical Reports Server (NTRS)

Sud, V. K.; Srinivasan, R. S.; Charles, J. B.; Bungo, M. W.

1992-01-01

The paper presents a detailed model of the entire human cardiovascular system which aims to study the changes in flow distribution caused by external stimuli, changes in internal parameters, or other factors. The arterial-venous network is represented by 325 interconnected elastic segments. The mathematical description of each segment is based on equations of hydrodynamics and those of stress/strain relationships in elastic materials. Appropriate input functions provide for the pumping of blood by the heart through the system. The analysis employs the finite-element technique which can accommodate any prescribed boundary conditions. Values of model parameters are from available data on physical and rheological properties of blood and blood vessels. As a representative example, simulation results on changes in flow distribution with changes in the elastic properties of blood vessels are discussed. They indicate that the errors in the calculated overall flow rates are not significant even in the extreme case of arteries and veins behaving as rigid tubes.

CFD methodology and validation for turbomachinery flows

NASA Astrophysics Data System (ADS)

Hirsch, Ch.

1994-05-01

The essential problem today, in the application of 3D Navier-Stokes simulations to the design and analysis of turbomachinery components, is the validation of the numerical approximation and of the physical models, in particular the turbulence modelling. Although most of the complex 3D flow phenomena occurring in turbomachinery bladings can be captured with relatively coarse meshes, many detailed flow features are dependent on mesh size, on the turbulence and transition models. A brief review of the present state of the art of CFD methodology is given with emphasis on quality and accuracy of numerical approximations related to viscous flow computations. Considerations related to the mesh influence on solution accuracy are stressed. The basic problems of turbulence and transition modelling are discussed next, with a short summary of the main turbulence models and their applications to representative turbomachinery flows. Validations of present turbulence models indicate that none of the available turbulence models is able to predict all the detailed flow behavior in complex flow interactions. In order to identify the phenomena that can be captured on coarser meshes a detailed understanding of the complex 3D flow in compressor and turbines is necessary. Examples of global validations for different flow configurations, representative of compressor and turbine aerodynamics are presented, including secondary and tip clearance flows.

Swellable elastomers under constraint

NASA Astrophysics Data System (ADS)

Lou, Yucun; Robisson, Agathe; Cai, Shengqiang; Suo, Zhigang

2012-08-01

Swellable elastomers are widely used in the oilfield to seal the flow of downhole fluids. For example, when a crack appears in self-healing cement, the liquid in the surroundings flows into the crack and permeates into the cement, causing small particles of elastomers in the cement to swell, resulting in the blocking of the flow. Elastomers are also used as large components in swellable packers, which can swell and seal zones in the borehole. In these applications, the elastomers swell against the constraint of stiff materials, such as cement, metal, and rock. The pressure generated by the elastomer against the confinement is a key factor that affects the quality of the sealing. This work develops a systematic approach to predict the magnitude of the pressure in such components. Experiments are carried out to determine the stress-stretch curve, free swelling ratio, and confining pressure. The data are interpreted in terms of a modified Flory-Rehner model.

Evolution of Lamb Vector as a Vortex Breaking into Turbulence.

NASA Astrophysics Data System (ADS)

Wu, J. Z.; Lu, X. Y.

1996-11-01

In an incompressible flow, either laminar or turbulent, the Lamb vector is solely responsible to nonlinear interactions. While its longitudinal part is balanced by stagnation enthalpy, its transverse part is the unique source (as an external forcing in spectral space) that causes the flow to evolve. Moreover, in Reynolds-averaged flows the turbulent force can be derived exclusively from the Lamb vector instead of the full Reynolds stress tensor. Therefore, studying the evolution of the Lamb vector itself (both longitudinal and transverse parts) is of great interest. We have numerically examined this problem, taking the nonlinear distabilization of a viscous vortex as an example. In the later stage of this evolution we introduced a forcing to keep a statistically steady state, and observed the Lamb vector behavior in the resulting fine turbulence. The result is presented in both physical and spectral spaces.

Hydrate morphology: Physical properties of sands with patchy hydrate saturation

USGS Publications Warehouse

Dai, S.; Santamarina, J.C.; Waite, William F.; Kneafsey, T.J.

2012-01-01

The physical properties of gas hydrate-bearing sediments depend on the volume fraction and spatial distribution of the hydrate phase. The host sediment grain size and the state of effective stress determine the hydrate morphology in sediments; this information can be used to significantly constrain estimates of the physical properties of hydrate-bearing sediments, including the coarse-grained sands subjected to high effective stress that are of interest as potential energy resources. Reported data and physical analyses suggest hydrate-bearing sands contain a heterogeneous, patchy hydrate distribution, whereby zones with 100% pore-space hydrate saturation are embedded in hydrate-free sand. Accounting for patchy rather than homogeneous hydrate distribution yields more tightly constrained estimates of physical properties in hydrate-bearing sands and captures observed physical-property dependencies on hydrate saturation. For example, numerical modeling results of sands with patchy saturation agree with experimental observation, showing a transition in stiffness starting near the series bound at low hydrate saturations but moving toward the parallel bound at high hydrate saturations. The hydrate-patch size itself impacts the physical properties of hydrate-bearing sediments; for example, at constant hydrate saturation, we find that conductivity (electrical, hydraulic and thermal) increases as the number of hydrate-saturated patches increases. This increase reflects the larger number of conductive flow paths that exist in specimens with many small hydrate-saturated patches in comparison to specimens in which a few large hydrate saturated patches can block flow over a significant cross-section of the specimen.

Hydraulic Reconstructions of Outburst Floods on Earth and Mars

NASA Astrophysics Data System (ADS)

Lapotre, M. G. A.; Lamb, M. P.

2014-12-01

Large outburst floods on Earth and Mars have carved bedrock canyons in basalt that often have steep sidewalls and amphitheater heads, suggesting erosion by waterfall retreat and block toppling. Two paleohydraulic methods are typically used to reconstruct flood discharges. The first is based on the discharge required to move sediment, which requires rare grain-size data and is necessarily a lower bound. The second assumes bedrock canyons are entirely inundated, which likely greatly overestimates the discharge of canyon carving floods. Here we explore a third hypothesis that canyon width is an indicator of flood discharge. For example, we expect that for large floods relative to the canyon width, the canyon will tend to widen as water spills over and erodes the canyon sidewalls. In contrast, small floods, relative to the canyon size will tend to focus flow into the canyon head, resulting in a narrowing canyon. To test this hypothesis, we need data on how outburst floods focus water into canyons across a wide range of canyon and flood sizes. To fill this data gap, we performed a series of numerical simulations solving the 2D depth-averaged shallow water equations for turbulent flow. We analyzed the effect of five non-dimensional parameters on the shear stress and discharge distributions around head and sidewalls of canyons of different sizes. The Froude number of the flood has the greatest effect on the distribution of shear stresses and discharges around the canyon rim; higher Froude numbers lead to less convergence of the flow towards the canyon, and thus to lower shear stresses (and discharges) on the sides of the canyon. Simulation results show that canyons of constant width were likely carved by floods within a relatively narrow range of discharges. The range of discharges is sensitive to the Froude number and size of blocks that are toppled at the canyon head, both of which can be estimated from field and remotely sensed data. Example applications on Earth and Mars show that our flood reconstructions yield canyon-carving discharges larger than inferred from incipient motion thresholds, and often dramatically smaller than inferred from assuming complete canyon inundation.

The imperative for controlled mechanical stresses in unraveling cellular mechanisms of mechanotransduction

PubMed Central

Anderson, Eric J; Falls, Thomas D; Sorkin, Adam M; Tate, Melissa L Knothe

2006-01-01

Background In vitro mechanotransduction studies are designed to elucidate cell behavior in response to a well-defined mechanical signal that is imparted to cultured cells, e.g. through fluid flow. Typically, flow rates are calculated based on a parallel plate flow assumption, to achieve a targeted cellular shear stress. This study evaluates the performance of specific flow/perfusion chambers in imparting the targeted stress at the cellular level. Methods To evaluate how well actual flow chambers meet their target stresses (set for 1 and 10 dyn/cm2 for this study) at a cellular level, computational models were developed to calculate flow velocity components and imparted shear stresses for a given pressure gradient. Computational predictions were validated with micro-particle image velocimetry (μPIV) experiments. Results Based on these computational and experimental studies, as few as 66% of cells seeded along the midplane of commonly implemented flow/perfusion chambers are subjected to stresses within ±10% of the target stress. In addition, flow velocities and shear stresses imparted through fluid drag vary as a function of location within each chamber. Hence, not only a limited number of cells are exposed to target stress levels within each chamber, but also neighboring cells may experience different flow regimes. Finally, flow regimes are highly dependent on flow chamber geometry, resulting in significant variation in magnitudes and spatial distributions of stress between chambers. Conclusion The results of this study challenge the basic premise of in vitro mechanotransduction studies, i.e. that a controlled flow regime is applied to impart a defined mechanical stimulus to cells. These results also underscore the fact that data from studies in which different chambers are utilized can not be compared, even if the target stress regimes are comparable. PMID:16672051

Mechanochemical pattern formation in simple models of active viscoelastic fluids and solids

NASA Astrophysics Data System (ADS)

Alonso, Sergio; Radszuweit, Markus; Engel, Harald; Bär, Markus

2017-11-01

The cytoskeleton of the organism Physarum polycephalum is a prominent example of a complex active viscoelastic material wherein stresses induce flows along the organism as a result of the action of molecular motors and their regulation by calcium ions. Experiments in Physarum polycephalum have revealed a rich variety of mechanochemical patterns including standing, traveling and rotating waves that arise from instabilities of spatially homogeneous states without gradients in stresses and resulting flows. Herein, we investigate simple models where an active stress induced by molecular motors is coupled to a model describing the passive viscoelastic properties of the cellular material. Specifically, two models for viscoelastic fluids (Maxwell and Jeffrey model) and two models for viscoelastic solids (Kelvin-Voigt and Standard model) are investigated. Our focus is on the analysis of the conditions that cause destabilization of spatially homogeneous states and the related onset of mechano-chemical waves and patterns. We carry out linear stability analyses and numerical simulations in one spatial dimension for different models. In general, sufficiently strong activity leads to waves and patterns. The primary instability is stationary for all active fluids considered, whereas all active solids have an oscillatory primary instability. All instabilities found are of long-wavelength nature reflecting the conservation of the total calcium concentration in the models studied.

Ideal flow theory for the double - shearing model as a basis for metal forming design

NASA Astrophysics Data System (ADS)

Alexandrov, S.; Trung, N. T.

2018-02-01

In the case of Tresca’ solids (i.e. solids obeying the Tresca yield criterion and its associated flow rule) ideal flows have been defined elsewhere as solenoidal smooth deformations in which an eigenvector field associated everywhere with the greatest principal stress (and strain rate) is fixed in the material. Under such conditions all material elements undergo paths of minimum plastic work, a condition which is often advantageous for metal forming processes. Therefore, the ideal flow theory is used as the basis of a procedure for the preliminary design of such processes. The present paper extends the theory of stationary planar ideal flow to pressure dependent materials obeying the double shearing model and the double slip and rotation model. It is shown that the original problem of plasticity reduces to a purely geometric problem. The corresponding system of equations is hyperbolic. The characteristic relations are integrated in elementary functions. In regions where one family of characteristics is straight, mapping between the principal lines and Cartesian coordinates is determined by linear ordinary differential equations. An illustrative example is provided.

Biofluid Mechanics Education at U Michigan

NASA Astrophysics Data System (ADS)

Grotberg, James

2007-11-01

At the University of Michigan, biofluid mechanics is taught in the Department of Biomedical Engineering with cross-listing in Mechanical Engineering. The course has evolved over 25 years and serves advanced undergraduates and graduate students. The course description is as follows: BiomedE/MechE 476 Biofluid Mechanics. CATALOG DESCRIPTION: This is an intermediate level fluid mechanics course which uses examples from biotechnology processes and physiologic applications including cellular, cardiovascular, respiratory, ocular, renal, orthopedic, and gastrointestinal systems. COURSE TOPICS: 1. Dimensional analysis (gastrointestinal, renal) 2. Approximation methods, numerical methods (biotechnology, respiratory) 3. Particle kinematics in Eulerian and Lagrangian references frames (biotechnology, respiratory) 4. Conservation of mass and momentum 5. Constitutive equations (blood, mucus) 6. Kinematic and stress boundary conditions: rigid, flexible, porous (cardio-pulmonary, cellular) 7. Surface tension phenomena (pulmonary, ocular) 8. Flow and wave propagation in flexible tubes (cardio-pulmonary) 9. Oscillatory and pulsatile flows (cardio-pulmonary, orthopedic) 10. High Reynolds number flows (cardio-pulmonary) 11. Low Reynolds number flows (biotechnology, cellular, vascular) 12. Lubrication theory (vascular, orthopedic) 13. Flow in poroelastic media (orthopedic, pulmonary, ocular) 14. Video presentations of laboratory experiments.

User's guide of TOUGH2-EGS-MP: A Massively Parallel Simulator with Coupled Geomechanics for Fluid and Heat Flow in Enhanced Geothermal Systems VERSION 1.0

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xiong, Yi; Fakcharoenphol, Perapon; Wang, Shihao

2013-12-01

TOUGH2-EGS-MP is a parallel numerical simulation program coupling geomechanics with fluid and heat flow in fractured and porous media, and is applicable for simulation of enhanced geothermal systems (EGS). TOUGH2-EGS-MP is based on the TOUGH2-MP code, the massively parallel version of TOUGH2. In TOUGH2-EGS-MP, the fully-coupled flow-geomechanics model is developed from linear elastic theory for thermo-poro-elastic systems and is formulated in terms of mean normal stress as well as pore pressure and temperature. Reservoir rock properties such as porosity and permeability depend on rock deformation, and the relationships between these two, obtained from poro-elasticity theories and empirical correlations, are incorporatedmore » into the simulation. This report provides the user with detailed information on the TOUGH2-EGS-MP mathematical model and instructions for using it for Thermal-Hydrological-Mechanical (THM) simulations. The mathematical model includes the fluid and heat flow equations, geomechanical equation, and discretization of those equations. In addition, the parallel aspects of the code, such as domain partitioning and communication between processors, are also included. Although TOUGH2-EGS-MP has the capability for simulating fluid and heat flows coupled with geomechanical effects, it is up to the user to select the specific coupling process, such as THM or only TH, in a simulation. There are several example problems illustrating applications of this program. These example problems are described in detail and their input data are presented. Their results demonstrate that this program can be used for field-scale geothermal reservoir simulation in porous and fractured media with fluid and heat flow coupled with geomechanical effects.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Srivastava, Nimisha; Singh, Anup K

Microfluidic devices and methods for flow cytometry are described. In described examples, various sample handling and preparation steps may be carried out within a same microfluidic device as flow cytometry steps. A combination of imaging and flow cytometry is described. In some examples, spiral microchannels serve as incubation chambers. Examples of automated sample handling and flow cytometry are described.

Gravity-driven groundwater flow and slope failure potential: 1. Elastic effective-stress model

USGS Publications Warehouse

Iverson, Richard M.; Reid, Mark E.

1992-01-01

Hilly or mountainous topography influences gravity-driven groundwater flow and the consequent distribution of effective stress in shallow subsurface environments. Effective stress, in turn, influences the potential for slope failure. To evaluate these influences, we formulate a two-dimensional, steady state, poroelastic model. The governing equations incorporate groundwater effects as body forces, and they demonstrate that spatially uniform pore pressure changes do not influence effective stresses. We implement the model using two finite element codes. As an illustrative case, we calculate the groundwater flow field, total body force field, and effective stress field in a straight, homogeneous hillslope. The total body force and effective stress fields show that groundwater flow can influence shear stresses as well as effective normal stresses. In most parts of the hillslope, groundwater flow significantly increases the Coulomb failure potential Φ, which we define as the ratio of maximum shear stress to mean effective normal stress. Groundwater flow also shifts the locus of greatest failure potential toward the slope toe. However, the effects of groundwater flow on failure potential are less pronounced than might be anticipated on the basis of a simpler, one-dimensional, limit equilibrium analysis. This is a consequence of continuity, compatibility, and boundary constraints on the two-dimensional flow and stress fields, and it points to important differences between our elastic continuum model and limit equilibrium models commonly used to assess slope stability.

Stress-Displacement Relations and Terrain-Vehicle Mechanics: A Critical Discussion

DTIC Science & Technology

1968-12-01

a definitl.! coherent r nttcrn of rupture surfaces if the geometrica l and load conditions are n t a !ta cG !1y .he flow process itself. The...4 (as shown for one example at <he bo tom of the fiaurc). After application of the appropriate correction factor to account for the diftcrent tan...Sela’s theory is correct . Jtouahly 50 per r.ent of the experimental M I RW curves arc beyond these limits, wlllcla IIIIDituiBcieat to reject SoJa’s

Climatic and anthropogenic changes in Western Switzerland: Impacts on water stress.

PubMed

Milano, Marianne; Reynard, Emmanuel; Köplin, Nina; Weingartner, Rolf

2015-12-01

Recent observed hydro-climatic changes in mountainous areas are of concern as they may directly affect capacity to fulfill water needs. The canton of Vaud in Western Switzerland is an example of such a region as it has experienced water shortage episodes during the past decade. Based on an integrated modeling framework, this study explores how hydro-climatic conditions and water needs could evolve in mountain environments and assesses their potential impacts on water stress by the 2060 horizon. Flows were simulated based on a daily semi-distributed hydrological model. Future changes were derived from Swiss climate scenarios based on two regional climate models. Regarding water needs, the authorities of the canton of Vaud provided a population growth scenario while irrigation and livestock trends followed a business-as-usual scenario. Currently, the canton of Vaud experiences moderate water stress from June to August, except in its Alpine area where no stress is noted. In the 2060 horizon, water needs could exceed 80% of the rivers' available resources in low- to mid-altitude environments in mid-summer. This arises from the combination of drier and warmer climate that leads to longer and more severe low flows, and increasing urban (+40%) and irrigation (+25%) water needs. Highlighting regional differences supports the development of sustainable development pathways to reduce water tensions. Based on a quantitative assessment, this study also calls for broader impact studies including water quality issues. Copyright © 2015 Elsevier B.V. All rights reserved.

Reactive oxygen species, oxidative stress, glaucoma and hyperbaric oxygen therapy.

PubMed

McMonnies, Charles

This review examines the role of oxidative stress in damage to cells of the trabecular meshwork and associated impaired aqueous drainage as well as damage to retinal ganglion cells and associated visual field losses. Consideration is given to the interaction between vascular and mechanical explanations for pathological changes in glaucoma. For example, elevated intraocular pressure (IOP) forces may contribute to ischaemia but there is increasing evidence that altered blood flow in a wider sense is also involved. Both vascular and mechanical theories are involved through fluctuations in intraocular pressure and dysregulation of blood flow. Retinal function is very sensitive to changes in haemoglobin oxygen concentration and the associated variations in the production of reactive oxygen species. Reperfusion injury and production of reactive oxygen species occurs when IOP is elevated or blood pressure is low and beyond the capacity for blood flow autoregulation to maintain appropriate oxygen concentration. Activities such as those associated with postural changes, muscular effort, eye wiping and rubbing which cause IOP fluctuation, may have significant vascular, mechanical, reperfusion and oxidative stress consequences. Hyperbaric oxygen therapy exposes the eye to increased oxygen concentration and the risk of oxidative damage in susceptible individuals. However, oxygen concentration in aqueous humour, and the risk of damage to trabecular meshwork cells may be greater if hyperbaric oxygen is delivered by a hood which exposes the anterior ocular surface to higher than normal oxygen levels. Oronasal mask delivery of hyperbaric oxygen therapy appears to be indicated in these cases. Copyright © 2017 Spanish General Council of Optometry. Published by Elsevier España, S.L.U. All rights reserved.

Time-dependent rheological behavior of natural polysaccharide xanthan gum solutions in interrupted shear and step-incremental/reductional shear flow fields

NASA Astrophysics Data System (ADS)

Lee, Ji-Seok; Song, Ki-Won

2015-11-01

The objective of the present study is to systematically elucidate the time-dependent rheological behavior of concentrated xanthan gum systems in complicated step-shear flow fields. Using a strain-controlled rheometer (ARES), step-shear flow behaviors of a concentrated xanthan gum model solution have been experimentally investigated in interrupted shear flow fields with a various combination of different shear rates, shearing times and rest times, and step-incremental and step-reductional shear flow fields with various shearing times. The main findings obtained from this study are summarized as follows. (i) In interrupted shear flow fields, the shear stress is sharply increased until reaching the maximum stress at an initial stage of shearing times, and then a stress decay towards a steady state is observed as the shearing time is increased in both start-up shear flow fields. The shear stress is suddenly decreased immediately after the imposed shear rate is stopped, and then slowly decayed during the period of a rest time. (ii) As an increase in rest time, the difference in the maximum stress values between the two start-up shear flow fields is decreased whereas the shearing time exerts a slight influence on this behavior. (iii) In step-incremental shear flow fields, after passing through the maximum stress, structural destruction causes a stress decay behavior towards a steady state as an increase in shearing time in each step shear flow region. The time needed to reach the maximum stress value is shortened as an increase in step-increased shear rate. (iv) In step-reductional shear flow fields, after passing through the minimum stress, structural recovery induces a stress growth behavior towards an equilibrium state as an increase in shearing time in each step shear flow region. The time needed to reach the minimum stress value is lengthened as a decrease in step-decreased shear rate.

Survey of Turbulence Models for the Computation of Turbulent Jet Flow and Noise

NASA Technical Reports Server (NTRS)

Nallasamy, N.

1999-01-01

The report presents an overview of jet noise computation utilizing the computational fluid dynamic solution of the turbulent jet flow field. The jet flow solution obtained with an appropriate turbulence model provides the turbulence characteristics needed for the computation of jet mixing noise. A brief account of turbulence models that are relevant for the jet noise computation is presented. The jet flow solutions that have been directly used to calculate jet noise are first reviewed. Then, the turbulent jet flow studies that compute the turbulence characteristics that may be used for noise calculations are summarized. In particular, flow solutions obtained with the k-e model, algebraic Reynolds stress model, and Reynolds stress transport equation model are reviewed. Since, the small scale jet mixing noise predictions can be improved by utilizing anisotropic turbulence characteristics, turbulence models that can provide the Reynolds stress components must now be considered for jet flow computations. In this regard, algebraic stress models and Reynolds stress transport models are good candidates. Reynolds stress transport models involve more modeling and computational effort and time compared to algebraic stress models. Hence, it is recommended that an algebraic Reynolds stress model (ASM) be implemented in flow solvers to compute the Reynolds stress components.

Relationship of stream ecological conditions to simulated hydraulic metrics across a gradient of basin urbanization

USGS Publications Warehouse

Steuer, J.J.; Bales, J.D.; Giddings, E.M.P.

2009-01-01

The relationships among urbanization, stream hydraulics, and aquatic biology were investigated across a gradient of urbanization in 30 small basins in eastern Wisconsin, USA. Simulation of hydraulic metrics with 1-dimensional unsteady flow models was an effective means for mechanistically coupling the effects of urbanization with stream ecological conditions (i.e., algae, invertebrates, and fish). Urbanization, characterized by household, road, and urban land density, was positively correlated with the lowest shear stress for 2 adjacent transects in a reach for the low-flow summer (p < 0.001) and autumn (p < 0.01) periods. Urbanization also was positively correlated with Reynolds number and % exposed stream bed during months with moderate to low flows. Our study demonstrated the value of temporally and spatially explicit hydraulic models for providing mechanistic insight into the relationships between hydraulic variables and biological responses. For example, the positive correlation between filter-feeding invertebrate richness and minimum 2-transect shear stress observed in our study is consistent with a higher concentration of water-column particulates available for filtration. The strength of correlations between hydraulic and biological metrics is related to the time period (annual, seasonal, or monthly) considered. The hydraulic modeling approach, whether based on hourly or daily flow data, allowed documentation of the effects of a spatially variable response within a reach, and the results suggest that stream response to urbanization varies with hydraulic habitat type. ?? North American Benthological Society.

Microstructure Evolution and Flow Stress Model of a 20Mn5 Hollow Steel Ingot during Hot Compression.

PubMed

Liu, Min; Ma, Qing-Xian; Luo, Jian-Bin

2018-03-21

20Mn5 steel is widely used in the manufacture of heavy hydro-generator shaft due to its good performance of strength, toughness and wear resistance. However, the hot deformation and recrystallization behaviors of 20Mn5 steel compressed under high temperature were not studied. In this study, the hot compression experiments under temperatures of 850-1200 °C and strain rates of 0.01/s-1/s are conducted using Gleeble thermal and mechanical simulation machine. And the flow stress curves and microstructure after hot compression are obtained. Effects of temperature and strain rate on microstructure are analyzed. Based on the classical stress-dislocation relation and the kinetics of dynamic recrystallization, a two-stage constitutive model is developed to predict the flow stress of 20Mn5 steel. Comparisons between experimental flow stress and predicted flow stress show that the predicted flow stress values are in good agreement with the experimental flow stress values, which indicates that the proposed constitutive model is reliable and can be used for numerical simulation of hot forging of 20Mn5 hollow steel ingot.

Yield-stress fluids foams: flow patterns and controlled production in T-junction and flow-focusing devices.

PubMed

Laborie, Benoit; Rouyer, Florence; Angelescu, Dan E; Lorenceau, Elise

2016-11-23

We study the formation of yield-stress fluid foams in millifluidic flow-focusing and T-junction devices. First, we provide a phase diagram for the unsteady operating regimes of bubble production when the gas pressure and the yield-stress fluid flow rate are imposed. Three regimes are identified: a co-flow of gas and yield-stress fluid, a transient production of bubble and a flow of yield-stress fluid only. Taking wall slip into account, we provide a model for the pressure at the onset of bubble formation. Then, we detail and compare two simple methods to ensure steady bubble production: regulation of the gas pressure or flow-rate. These techniques, which are easy to implement, thus open pathways for controlled production of dry yield-stress fluid foams as shown at the end of this article.

User's Guide of TOUGH2-EGS. A Coupled Geomechanical and Reactive Geochemical Simulator for Fluid and Heat Flow in Enhanced Geothermal Systems Version 1.0

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fakcharoenphol, Perapon; Xiong, Yi; Hu, Litang

TOUGH2-EGS is a numerical simulation program coupling geomechanics and chemical reactions for fluid and heat flows in porous media and fractured reservoirs of enhanced geothermal systems. The simulator includes the fully-coupled geomechanical (THM) module, the fully-coupled geochemical (THC) module, and the sequentially coupled reactive geochemistry (THMC) module. The fully-coupled flow-geomechanics model is developed from the linear elastic theory for the thermo-poro-elastic system and is formulated with the mean normal stress as well as pore pressure and temperature. The chemical reaction is sequentially coupled after solution of flow equations, which provides the flow velocity and phase saturation for the solute transportmore » calculation at each time step. In addition, reservoir rock properties, such as porosity and permeability, are subjected to change due to rock deformation and chemical reactions. The relationships between rock properties and geomechanical and chemical effects from poro-elasticity theories and empirical correlations are incorporated into the simulator. This report provides the user with detailed information on both mathematical models and instructions for using TOUGH2-EGS for THM, THC or THMC simulations. The mathematical models include the fluid and heat flow equations, geomechanical equation, reactive geochemistry equations, and discretization methods. Although TOUGH2-EGS has the capability for simulating fluid and heat flows coupled with both geomechanical and chemical effects, it is up to the users to select the specific coupling process, such as THM, THC, or THMC in a simulation. There are several example problems illustrating the applications of this program. These example problems are described in details and their input data are presented. The results demonstrate that this program can be used for field-scale geothermal reservoir simulation with fluid and heat flow, geomechanical effect, and chemical reaction in porous and fractured media.« less

Effects of debris-flow composition on runout and erosion

NASA Astrophysics Data System (ADS)

Haas, T. D.; Kleinhans, M. G.

2016-12-01

Predicting debris-flow runout is of major importance for hazard mitigation. Apart from topography and volume, runout depends on debris-flow composition (i.e., particle-size distribution and water content), but how is poorly understood. Moreover, debris flows can grow greatly in size by entrainment of bed material, enhancing their volume and thereby runout and hazardous impact. Debris-flow erosion rates also depend on debris-flow composition, but the relation between the two is largely unexplored. Composition thus strongly affects the dynamics of debris flows. We experimentally investigate the effects of composition on debris-flow runout and erosion. We find a clear optimum in the relations of runout with coarse-material fraction and clay fraction. Increasing coarse material concentration leads to larger runout. However, excess coarse material results in a large accumulation of coarse debris at the flow front and enhances diffusivity, increasing frontal friction and decreasing runout. Increasing clay content initially enhances runout, but too much clay leads to very viscous flows, reducing runout. We further find that debris-flow runout depends at least as much on composition as on topography. In general, erosion depth increases with basal shear stress in our experiments, while there is no correlation with grain collisional stress. There are substantial differences in the scour caused by different types of debris flows. Mean and maximum erosion depths generally become larger with increasing water fraction and grain size and decrease with increasing clay content. However, the erodibility of the very coarse-grained experimental debris flows is unrelated to basal shear stress. This relates to the relatively large influence of grain-collisional stress to the total bed stress in these flows (30-50%). The relative effect of grain-collisional stress is low in the other experimental debris flows (<5%) causing erosion to be largely controlled by basal shear stress. These results show that the erosive behaviour of debris flows may change from basal-shear stress dominated to grain-collisional stress dominated in increasingly coarse-grained debris flows. In short, this study improves our understanding of the effects of debris-flow composition on runout and erosion.

Renal sympathetic nerve, blood flow, and epithelial transport responses to thermal stress.

PubMed

Wilson, Thad E

2017-05-01

Thermal stress is a profound sympathetic stress in humans; kidney responses involve altered renal sympathetic nerve activity (RSNA), renal blood flow, and renal epithelial transport. During mild cold stress, RSNA spectral power but not total activity is altered, renal blood flow is maintained or decreased, and epithelial transport is altered consistent with a sympathetic stress coupled with central volume loaded state. Hypothermia decreases RSNA, renal blood flow, and epithelial transport. During mild heat stress, RSNA is increased, renal blood flow is decreased, and epithelial transport is increased consistent with a sympathetic stress coupled with a central volume unloaded state. Hyperthermia extends these directional changes, until heat illness results. Because kidney responses are very difficult to study in humans in vivo, this review describes and qualitatively evaluates an in vivo human skin model of sympathetically regulated epithelial tissue compared to that of the nephron. This model utilizes skin responses to thermal stress, involving 1) increased skin sympathetic nerve activity (SSNA), decreased skin blood flow, and suppressed eccrine epithelial transport during cold stress; and 2) increased SSNA, skin blood flow, and eccrine epithelial transport during heat stress. This model appears to mimic aspects of the renal responses. Investigations of skin responses, which parallel certain renal responses, may aid understanding of epithelial-sympathetic nervous system interactions during cold and heat stress. Copyright © 2016 Elsevier B.V. All rights reserved.

Assessment of turbulent viscous stress using ICOSA 4D Flow MRI for prediction of hemodynamic blood damage

NASA Astrophysics Data System (ADS)

Ha, Hojin; Lantz, Jonas; Haraldsson, Henrik; Casas, Belen; Ziegler, Magnus; Karlsson, Matts; Saloner, David; Dyverfeldt, Petter; Ebbers, Tino

2016-12-01

Flow-induced blood damage plays an important role in determining the hemodynamic impact of abnormal blood flow, but quantifying of these effects, which are dominated by shear stresses in highly fluctuating turbulent flow, has not been feasible. This study evaluated the novel application of turbulence tensor measurements using simulated 4D Flow MRI data with six-directional velocity encoding for assessing hemodynamic stresses and corresponding blood damage index (BDI) in stenotic turbulent blood flow. The results showed that 4D Flow MRI underestimates the maximum principal shear stress of laminar viscous stress (PLVS), and overestimates the maximum principal shear stress of Reynolds stress (PRSS) with increasing voxel size. PLVS and PRSS were also overestimated by about 1.2 and 4.6 times at medium signal to noise ratio (SNR) = 20. In contrast, the square sum of the turbulent viscous shear stress (TVSS), which is used for blood damage index (BDI) estimation, was not severely affected by SNR and voxel size. The square sum of TVSS and the BDI at SNR >20 were underestimated by less than 1% and 10%, respectively. In conclusion, this study demonstrated the feasibility of 4D Flow MRI based quantification of TVSS and BDI which are closely linked to blood damage.

Microstructure Evolution and Flow Stress Model of a 20Mn5 Hollow Steel Ingot during Hot Compression

PubMed Central

Liu, Min; Ma, Qing-Xian; Luo, Jian-Bin

2018-01-01

20Mn5 steel is widely used in the manufacture of heavy hydro-generator shaft due to its good performance of strength, toughness and wear resistance. However, the hot deformation and recrystallization behaviors of 20Mn5 steel compressed under high temperature were not studied. In this study, the hot compression experiments under temperatures of 850–1200 °C and strain rates of 0.01/s–1/s are conducted using Gleeble thermal and mechanical simulation machine. And the flow stress curves and microstructure after hot compression are obtained. Effects of temperature and strain rate on microstructure are analyzed. Based on the classical stress-dislocation relation and the kinetics of dynamic recrystallization, a two-stage constitutive model is developed to predict the flow stress of 20Mn5 steel. Comparisons between experimental flow stress and predicted flow stress show that the predicted flow stress values are in good agreement with the experimental flow stress values, which indicates that the proposed constitutive model is reliable and can be used for numerical simulation of hot forging of 20Mn5 hollow steel ingot. PMID:29561826

Doppler optical coherence tomography imaging of local fluid flow and shear stress within microporous scaffolds

NASA Astrophysics Data System (ADS)

Jia, Yali; Bagnaninchi, Pierre O.; Yang, Ying; Haj, Alicia El; Hinds, Monica T.; Kirkpatrick, Sean J.; Wang, Ruikang K.

2009-05-01

Establishing a relationship between perfusion rate and fluid shear stress in a 3D cell culture environment is an ongoing and challenging task faced by tissue engineers. We explore Doppler optical coherence tomography (DOCT) as a potential imaging tool for in situ monitoring of local fluid flow profiles inside porous chitosan scaffolds. From the measured fluid flow profiles, the fluid shear stresses are evaluated. We examine the localized fluid flow and shear stress within low- and high-porosity chitosan scaffolds, which are subjected to a constant input flow rate of 0.5 ml.min-1. The DOCT results show that the behavior of the fluid flow and shear stress in micropores is strongly dependent on the micropore interconnectivity, porosity, and size of pores within the scaffold. For low-porosity and high-porosity chitosan scaffolds examined, the measured local fluid flow and shear stress varied from micropore to micropore, with a mean shear stress of 0.49+/-0.3 dyn.cm-2 and 0.38+/-0.2 dyn.cm-2, respectively. In addition, we show that the scaffold's porosity and interconnectivity can be quantified by combining analyses of the 3D structural and flow images obtained from DOCT.

A critical assessment of viscous models of trench topography and corner flow

NASA Technical Reports Server (NTRS)

Zhang, J.; Hager, B. H.; Raefsky, A.

1984-01-01

Stresses for Newtonian viscous flow in a simple geometry (e.g., corner flow, bending flow) are obtained in order to study the effect of imposed velocity boundary conditions. Stress for a delta function velocity boundary condition decays as 1/R(2); for a step function velocity, stress goes as 1/R; for a discontinuity in curvature, the stress singularity is logarithmic. For corner flow, which has a discontinuity of velocity at a certain point, the corresponding stress has a 1/R singularity. However, for a more realistic circular-slab model, the stress singularity becomes logarithmic. Thus the stress distribution is very sensitive to the boundary conditions, and in evaluating the applicability of viscous models of trench topography it is essential to use realistic geometries. Topography and seismicity data from northern Hoshu, Japan, were used to construct a finite element model, with flow assumed tangent to the top of the grid, for both Newtonian and non-Newtonian flow (power law 3 rheology). Normal stresses at the top of the grid are compared to the observed trench topography and gravity anomalies. There is poor agreement. Purely viscous models of subducting slables with specified velocity boundary conditions do not predict normal stress patterns compatible with observed topography and gravity. Elasticity and plasticity appear to be important for the subduction process.

Lattice Boltzmann Model of 3D Multiphase Flow in Artery Bifurcation Aneurysm Problem

PubMed Central

Abas, Aizat; Mokhtar, N. Hafizah; Ishak, M. H. H.; Abdullah, M. Z.; Ho Tian, Ang

2016-01-01

This paper simulates and predicts the laminar flow inside the 3D aneurysm geometry, since the hemodynamic situation in the blood vessels is difficult to determine and visualize using standard imaging techniques, for example, magnetic resonance imaging (MRI). Three different types of Lattice Boltzmann (LB) models are computed, namely, single relaxation time (SRT), multiple relaxation time (MRT), and regularized BGK models. The results obtained using these different versions of the LB-based code will then be validated with ANSYS FLUENT, a commercially available finite volume- (FV-) based CFD solver. The simulated flow profiles that include velocity, pressure, and wall shear stress (WSS) are then compared between the two solvers. The predicted outcomes show that all the LB models are comparable and in good agreement with the FVM solver for complex blood flow simulation. The findings also show minor differences in their WSS profiles. The performance of the parallel implementation for each solver is also included and discussed in this paper. In terms of parallelization, it was shown that LBM-based code performed better in terms of the computation time required. PMID:27239221

Double-trace flows and the swampland

NASA Astrophysics Data System (ADS)

Giombi, Simone; Perlmutter, Eric

2018-03-01

We explore the idea that large N, non-supersymmetric conformal field theories with a parametrically large gap to higher spin single-trace operators may be obtained as infrared fixed points of relevant double-trace deformations of superconformal field theories. After recalling the AdS interpretation and some potential pathologies of such flows, we introduce a concrete example that appears to avoid them: the ABJM theory at finite k, deformed by \\int O^2, where O is the superconformal primary in the stress-tensor multiplet. We address its relation to recent conjectures based on weak gravity bounds, and discuss the prospects for a wider class of similarly viable flows. Next, we proceed to analyze the spectrum and correlation functions of the putative IR CFT, to leading non-trivial order in 1 /N. This includes analytic computations of the change under double-trace flow of connected four-point functions of ABJM superconformal primaries; and of the IR anomalous dimensions of infinite classes of double-trace composite operators. These would be the first analytic results for anomalous dimensions of finite-spin composite operators in any large N CFT3 with an Einstein gravity dual.

Streambed stresses and flow around bridge piers

USGS Publications Warehouse

Parola, A.C.; Ruhl, K.J.; Hagerty, D.J.; Brown, B.M.; Ford, D.L.; Korves, A.A.

1996-01-01

Scour of streambed material around bridge foundations by floodwaters is the leading cause of catastrophic bridge failure in the United States. The potential for scour and the stability of riprap used to protect the streambed from scour during extreme flood events must be known to evaluate the likelihood of bridge failure. A parameter used in estimating the potential for scour and removal of riprap protection is the time-averaged shear stress on the streambed often referred to as boundary stress. Bridge components, such as bridge piers and abutments, obstruct flow and induce strong vortex systems that create streambed or boundary stresses significantly higher than those in unobstructed flow. These locally high stresses can erode the streambed around pier and abutment foundations to the extent that the foundation is undermined, resulting in settlement or collapse of bridge spans. The purpose of this study was to estimate streambed stresses at a bridge pier under full-scale flow conditions and to compare these stresses with those obtained previously in small-scale model studies. Two-dimensional velocity data were collected for three flow conditions around a bridge pier at the Kentucky State Highway 417 bridge over the Green River at Greensburg in Green County, Ky. Velocity vector plots and the horizontal component of streambed stress contour plots were developed from the velocity data. The streambed stress contours were developed using both a near-bed velocity and velocity gradient method. Maximum near-bed velocities measured at the pier for the three flow conditions were 1.5, 1.6, and 2.0 times the average near-bed velocities measured in the upstream approach flow. Maximum streambed stresses for the three flow conditions were determined to be 10, 15, and 36 times the streambed stresses of the upstream approach flow. Both the near-bed velocity measurements and approximate maximum streambed stresses at the full-scale pier were consistent with those observed in experiments using small-scale models in which similar data were collected, except for a single observation of the near-bed velocity data and the corresponding streambed stress determination. The location of the maximum streambed stress was immediately downstream of a 90 degree radial of the upstream cylinder (with the center of the upstream cylinder being the origin) for the three flow conditions. This location was close to the flow wake separation point at the upstream cylinder. Other researchers have observed the maximum streambed stress around circular cylinders at this location or at a location immediately upstream of the wake separation point. Although the magnitudes of the estimated streambed stresses measured at the full-scale pier were consistent with those measured in small-scale model studies, the stress distributions were significantly different than those measured in small-scale models. The most significant discrepancies between stress contours developed in this study and those developed in the small-scale studies for flow around cylindrical piers on a flat streambed were associated with the shape of the stress contours. The extent of the high stress region of the streambed around the full-scale pier was substantially larger than the diameter of the upstream cylinder, while small-scale models had small regions compared to the diameter of the model cylinders. In addition, considerable asymmetry in the stress contours was observed. The large region of high stress and asymmetry was attributed to several factors including (1) the geometry of the full-scale pier, (2) the non-planar topography of the streambed, (3) the 20 degree skew of the pier to the approaching flow, and (4) the non-uniformity of the approach flow. The extent of effect of the pier on streambed stresses was found to be larger for the full-scale site than for model studies. The results from the model studies indicated that the streambed stresses created by the obstruction of flow by the 3-foot wide pi

Fracture, fluid flow and paleostress at Sunrise Dam Gold Mine, W. Australia

NASA Astrophysics Data System (ADS)

Blenkinsop, Thomas; Sanderson, David; Nugus, Michael

2017-04-01

Some of the clearest examples of Interactions between fracture, fluid flow, pore fluid pressure and differential stress can be inferred from underground observations in mines. This study examines the inferred stress conditions and resulting fracture network that constitutes a stockwork type ore body at Sunrise Dam gold mine, Western Australia. Stockworks in mine workings are particularly instructive for such analyses, because the abundance of veins allows cross-cutting relationships to be observed, which are commonly hard to see in situations of lower fracture intensity or incomplete outcrop. Sunrise Dam has produced in excess of 8.5Moz of gold since 1989, with current Mineral Resources and Ore Reserves at 58.96Mt@2.41g/t Au (4.55Moz) and 21.45Mt@1.87g/t Au (1.29Moz), respectively. The stockwork examined is in the Astro ore body, and consists of three sets of extensional veins and one set of low-angle strike-slip shear veins. Cross-cutting relationships suggest broadly contemporaneous formation of all fracture sets, which are also related by a common quartz-carbonate mineralogy. The extensional veins intersect the shear veins along the direction of shear, a geometry that can be predicted for certain stress ratios. Combined with observations and paleostress inferences from other parts of the mine, the veining and gold mineralisation can be associated with a D4 strike-slip shearing event, which had a maximum compressive stress plunging gently NE. Fracture intensity varies by 50% on a scale of 10s of metres. The stockwork formed by repeated extensional and shear failure events, showing fluctuations in pore fluid pressure and stress conditions, which would have required fracture healing/sealing in order for the deformation to spread throughout the stockwork volume.

Measuring Leukocyte Adhesion to (Primary) Endothelial Cells after Photon and Charged Particle Exposure with a Dedicated Laminar Flow Chamber

PubMed Central

Erbeldinger, Nadine; Rapp, Felicitas; Ktitareva, Svetlana; Wendel, Philipp; Bothe, Anna S.; Dettmering, Till; Durante, Marco; Friedrich, Thomas; Bertulat, Bianca; Meyer, Stephanie; Cardoso, M. C.; Hehlgans, Stephanie; Rödel, Franz; Fournier, Claudia

2017-01-01

The vascular endothelium interacts with all types of blood cells and is a key modulator of local and systemic inflammatory processes, for example, in the adhesion of blood leukocytes to endothelial cells (EC) and the following extravasation into the injured tissue. The endothelium is constantly exposed to mechanical forces caused by blood flow, and the resulting shear stress is essential for the maintenance of endothelial function. Changes in local hemodynamics are sensed by EC, leading to acute or persistent changes. Therefore, in vitro assessment of EC functionality should include shear stress as an essential parameter. Parallel-plate flow chambers with adjustable shear stress can be used to study EC properties. However, commercially available systems are not suitable for radiation experiments, especially with charged particles, which are increasingly used in radiotherapy of tumors. Therefore, research on charged-particle-induced vascular side effects is needed. In addition, α-particle emitters (e.g., radon) are used to treat inflammatory diseases at low doses. In the present study, we established a flow chamber system, applicable for the investigation of radiation induced changes in the adhesion of lymphocytes to EC as readout for the onset of an inflammatory reaction or the modification of a pre-existing inflammatory state. In this system, primary human EC are cultured under physiological laminar shear stress, subjected to a proinflammatory treatment and/or irradiation with X-rays or charged particles, followed by a coincubation with primary human lymphocytes (peripheral blood lymphocytes (PBL)). Analysis is performed by semiautomated quantification of fluorescent staining in microscopic pictures. First results obtained after irradiation with X-rays or helium ions indicate decreased adhesion of PBL to EC under laminar conditions for both radiation qualities, whereas adhesion of PBL under static conditions is not clearly affected by irradiation. Under static conditions, no radiation-induced changes in surface expression of adhesion molecules and activation of nuclear factor kappa B (NF-κB) signaling were observed after single cell-based high-throughput analysis. In subsequent studies, these investigations will be extended to laminar conditions. PMID:28620384

Shear flow of one-component polarizable fluid in a strong electric field

NASA Astrophysics Data System (ADS)

Sun, J. M.; Tao, R.

1996-04-01

A shear flow of one-component polarizable fluid in a strong electric field has a structural transition at a critical shear stress. When the shear stress is increased from zero up to the critical shear stress, the flow (in the x direction) has a flowing-chain (FC) structure, consisting of tilted or broken chains along the field (z direction). At the critical shear stress, the FC structure gives way to a flowing-hexagonal-layered (FHL) structure, consisting of several two-dimensional layers which are parallel to the x-z plane. Within one layer, particles form strings in the flow direction. Strings are constantly sliding over particles in strings right beneath. The effective viscosity drops dramatically at the structural change. As the shear stress reduces, the FHL structure persists even under a stress-free state if the thermal fluctuation is very weak. This structure change in the charging and discharging process produces a large hysteresis.

Nonlinear Reynolds stress model for turbulent shear flows

NASA Technical Reports Server (NTRS)

Barton, J. Michael; Rubinstein, R.; Kirtley, K. R.

1991-01-01

A nonlinear algebraic Reynolds stress model, derived using the renormalization group, is applied to equilibrium homogeneous shear flow and fully developed flow in a square duct. The model, which is quadratically nonlinear in the velocity gradients, successfully captures the large-scale inhomogeneity and anisotropy of the flows studied. The ratios of normal stresses, as well as the actual magnitudes of the stresses are correctly predicted for equilibrium homogeneous shear flow. Reynolds normal stress anisotropy and attendant turbulence driven secondary flow are predicted for a square duct. Profiles of mean velocity and normal stresses are in good agreement with measurements. Very close to walls, agreement with measurements diminishes. The model has the benefit of containing no arbitrary constants; all values are determined directly from the theory. It seems that near wall behavior is influenced by more than the large scale anisotropy accommodated in the current model. More accurate near wall calculations may well require a model for anisotropic dissipation.

Exact-solution for cone-plate viscometry

NASA Astrophysics Data System (ADS)

Giacomin, A. J.; Gilbert, P. H.

2017-11-01

The viscosity of a Newtonian fluid is often measured by confining the fluid to the gap between a rotating cone that is perpendicular to a fixed disk. We call this experiment cone-plate viscometry. When the cone angle approaches π/2 , the viscometer gap is called narrow. The shear stress in the fluid, throughout a narrow gap, hardly departs from the shear stress exerted on the plate, and we thus call cone-plate flow nearly homogeneous. In this paper, we derive an exact solution for this slight heterogeneity, and from this, we derive the correction factors for the shear rate on the cone and plate, for the torque, and thus, for the measured Newtonian viscosity. These factors thus allow the cone-plate viscometer to be used more accurately, and with cone-angles well below π/2 . We find cone-plate flow field heterogeneity to be far slighter than previously thought. We next use our exact solution for the velocity to arrive at the exact solution for the temperature rise, due to viscous dissipation, in cone-plate flow subject to isothermal boundaries. Since Newtonian viscosity is a strong function of temperature, we expect our new exact solution for the temperature rise be useful to those measuring Newtonian viscosity, and especially so, to those using wide gaps. We include two worked examples to teach practitioners how to use our main results.

Flow cytometry combined with viSNE for the analysis of microbial biofilms and detection of microplastics

PubMed Central

Sgier, Linn; Freimann, Remo; Zupanic, Anze; Kroll, Alexandra

2016-01-01

Biofilms serve essential ecosystem functions and are used in different technical applications. Studies from stream ecology and waste-water treatment have shown that biofilm functionality depends to a great extent on community structure. Here we present a fast and easy-to-use method for individual cell-based analysis of stream biofilms, based on stain-free flow cytometry and visualization of the high-dimensional data by viSNE. The method allows the combined assessment of community structure, decay of phototrophic organisms and presence of abiotic particles. In laboratory experiments, it allows quantification of cellular decay and detection of survival of larger cells after temperature stress, while in the field it enables detection of community structure changes that correlate with known environmental drivers (flow conditions, dissolved organic carbon, calcium) and detection of microplastic contamination. The method can potentially be applied to other biofilm types, for example, for inferring community structure for environmental and industrial research and monitoring. PMID:27188265

Influence of spatial variation of phenomenological parameters on the modeling of boundary conditions for flows with dynamic wetting

NASA Astrophysics Data System (ADS)

Hizumi, Yuka; Omori, Takeshi; Yamaguchi, Yasutaka; Kajisima, Takeo

2014-11-01

For reliable prediction of multiphase flows in micro- and nano-scales, continuum models are expected to account for small scale physics near the contact line (CL) region. Some existing works (for example the series of papers by the group of Qian and Ren) have been successful in deriving continuum models and corresponding boundary conditions which reproduce well the molecular dynamics (MD) simulation results. Their studies, however, did not fully address the issue of adsorption layer especially in the CL region, and it is still not clear if general conclusion can be deduced from their results. In the present study we investigate in detail the local viscosity and the corresponding stress tensor formulation in the solid-liquid interface and in the CL region of immiscible two-phase Couette flows by means of MD simulation. The application limit of the generalized Navier boundary condition and the continuum model with uniform viscosity is addressed by systematic coarse-graining of sampling bins.

Energy flow and the “grassification” of desert shrublands

USGS Publications Warehouse

Betancourt, Julio L.

2015-01-01

In our directionally and continuously changing world, history still matters, and it does so in increasingly novel and important ways. Human adaptation to global change will rely heavily on robust baselines of historic environmental variability and detailed understanding of how both past and modern ecosystems have responded to both individual and multiple stressors. The question of global change has motivated an upsurge in paleoecological studies that span the late Quaternary and the modern era, and has inspired a growing consideration of time as a fundamental axis in ecology (1). A major challenge in developing pertinent ecological baselines remains how to fuse, into continuous time series, observations and experiments from living systems with paleoecological reconstructions from the same sites (2, 3). Tracing and disentangling complex responses to environmental stress from paleological to present-day communities is especially daunting; for example, how climate change; accelerated land use; and biological invasions are influencing the flows of water, nutrients, and energy. The paper by Terry and Rowe in PNAS (4) is a shining example of how modern ecology and paleoecology can be spliced together to decipher how ecological processes unfold over time scales inaccessible to direct observation or experimentation, and how they can be disrupted by human impacts.

Normal stress effects on Knudsen flow

NASA Astrophysics Data System (ADS)

Eu, Byung Chan

2018-01-01

Normal stress effects are investigated on tube flow of a single-component non-Newtonian fluid under a constant pressure gradient in a constant temperature field. The generalized hydrodynamic equations are employed, which are consistent with the laws of thermodynamics. In the cylindrical tube flow configuration, the solutions of generalized hydrodynamic equations are exactly solvable and the flow velocity is obtained in a simple one-dimensional integral quadrature. Unlike the case of flow in the absence of normal stresses, the flow develops an anomaly in that the flow in the boundary layer becomes stagnant and the thickness of such a stagnant velocity boundary layer depends on the pressure gradient, the aspect ratio of the radius to the length of the tube, and the pressure (or density and temperature) at the entrance of the tube. The volume flow rate formula through the tube is derived for the flow. It generalizes the Knudsen flow rate formula to the case of a non-Newtonian stress tensor in the presence of normal stress differences. It also reduces to the Navier-Stokes theory formula in the low shear rate limit near equilibrium.

Rheology of Active Fluids

NASA Astrophysics Data System (ADS)

Saintillan, David

2018-01-01

An active fluid denotes a viscous suspension of particles, cells, or macromolecules able to convert chemical energy into mechanical work by generating stresses on the microscale. By virtue of this internal energy conversion, these systems display unusual macroscopic rheological signatures, including a curious transition to an apparent superfluid-like state where internal activity exactly compensates viscous dissipation. These behaviors are unlike those of classical complex fluids and result from the coupling of particle configurations with both externally applied flows and internally generated fluid disturbances. Focusing on the well-studied example of a suspension of microswimmers, this review summarizes recent experiments, models, and simulations in this area and highlights the critical role played by the rheological response of these active materials in a multitude of phenomena, from the enhanced transport of passive suspended objects to the emergence of spontaneous flows and collective motion.

Understanding casing flow in Pelton turbines by numerical simulation

NASA Astrophysics Data System (ADS)

Rentschler, M.; Neuhauser, M.; Marongiu, J. C.; Parkinson, E.

2016-11-01

For rehabilitation projects of Pelton turbines, the flow in the casing may have an important influence on the overall performance of the machine. Water sheets returning on the jets or on the runner significantly reduce efficiency, and run-away speed depends on the flow in the casing. CFD simulations can provide a detailed insight into this type of flow, but these simulations are computationally intensive. As in general the volume of water in a Pelton turbine is small compared to the complete volume of the turbine housing, a single phase simulation greatly reduces the complexity of the simulation. In the present work a numerical tool based on the SPH-ALE meshless method is used to simulate the casing flow in a Pelton turbine. Using improved order schemes reduces the numerical viscosity. This is necessary to resolve the flow in the jet and on the casing wall, where the velocity differs by two orders of magnitude. The results are compared to flow visualizations and measurement in a hydraulic laboratory. Several rehabilitation projects proved the added value of understanding the flow in the Pelton casing. The flow simulation helps designing casing insert, not only to see their influence on the flow, but also to calculate the stress in the inserts. In some projects, the casing simulation leads to the understanding of unexpected behavior of the flow. One such example is presented where the backsplash of a deflector hit the runner, creating a reversed rotation of the runner.

Measurement of Wall Shear Stress in High Speed Air Flow Using Shear-Sensitive Liquid Crystal Coating.

PubMed

Zhao, Jisong

2018-05-17

Wall shear stress is an important quantity in fluid mechanics, but its measurement is a challenging task. An approach to measure wall shear stress vector distribution using shear-sensitive liquid crystal coating (SSLCC) is described. The wall shear stress distribution on the test surface beneath high speed jet flow is measured while using the proposed technique. The flow structures inside the jet flow are captured and the results agree well with the streakline pattern that was visualized using the oil-flow technique. In addition, the shock diamonds inside the supersonic jet flow are visualized clearly using SSLCC and the results are compared with the velocity contour that was measured using the particle image velocimetry (PIV) technique. The work of this paper demonstrates the application of SSLCC in the measurement/visualization of wall shear stress in high speed flow.

Mean velocities and Reynolds stresses in a juncture flow

NASA Technical Reports Server (NTRS)

Mcmahon, H.; Hubbartt, J.; Kubendran, L.

1982-01-01

Values of three mean velocity components and six turbulence stresses measured in a juncture flow are presented and discussed. The juncture flow is generated by a constant thickness body, having an elliptical leading edge, which is mounted perpendicular to a large flat plate along which a turbulent boundary layer is growing. The measurements were carried out at two streamwise stations in the juncture and were made using two single sensor hot-wire probes. The secondary flow in the juncture results in a considerable distortion in the mean velocity profiles. The secondary flow also transports turbulence in the juncture flow and has a large effect on the turbulence stresses. From visual inspection of the results, there is considerable evidence of similarity between the turbulent shear stresses and the mean flow strain rates. There is some evidence of similarity between the variations in the turbulent stress components.

Measurement of Wall Shear Stress in High Speed Air Flow Using Shear-Sensitive Liquid Crystal Coating

PubMed Central

Zhao, Jisong

2018-01-01

Wall shear stress is an important quantity in fluid mechanics, but its measurement is a challenging task. An approach to measure wall shear stress vector distribution using shear-sensitive liquid crystal coating (SSLCC) is described. The wall shear stress distribution on the test surface beneath high speed jet flow is measured while using the proposed technique. The flow structures inside the jet flow are captured and the results agree well with the streakline pattern that was visualized using the oil-flow technique. In addition, the shock diamonds inside the supersonic jet flow are visualized clearly using SSLCC and the results are compared with the velocity contour that was measured using the particle image velocimetry (PIV) technique. The work of this paper demonstrates the application of SSLCC in the measurement/visualization of wall shear stress in high speed flow. PMID:29772822

Viscoelastic flow past mono- and bidisperse random arrays of cylinders: flow resistance, topology and normal stress distribution.

PubMed

De, S; Kuipers, J A M; Peters, E A J F; Padding, J T

2017-12-13

We investigate creeping viscoelastic fluid flow through two-dimensional porous media consisting of random arrangements of monodisperse and bidisperse cylinders, using our finite volume-immersed boundary method introduced in S. De, et al., J. Non-Newtonian Fluid Mech., 2016, 232, 67-76. The viscoelastic fluid is modeled with a FENE-P model. The simulations show an increased flow resistance with increase in flow rate, even though the bulk response of the fluid to shear flow is shear thinning. We show that if the square root of the permeability is chosen as the characteristic length scale in the determination of the dimensionless Deborah number (De), then all flow resistance curves collapse to a single master curve, irrespective of the pore geometry. Our study reveals how viscoelastic stresses and flow topologies (rotation, shear and extension) are distributed through the porous media, and how they evolve with increasing De. We correlate the local viscoelastic first normal stress differences with the local flow topology and show that the largest normal stress differences are located in shear flow dominated regions and not in extensional flow dominated regions at higher viscoelasticity. The study shows that normal stress differences in shear flow regions may play a crucial role in the increase of flow resistance for viscoelastic flow through such porous media.

Heat and Momentum Transfer Studies in High Reynolds Number Wavy Films at Normal and Reduced Gravity Conditions

NASA Technical Reports Server (NTRS)

Balakotaiah, V.

1996-01-01

We examined the effect of the gas flow on the liquid film when the gas flows in the countercurrent direction in a vertical pipe at normal gravity conditions. The most dramatic effect of the simultaneous flow of gas and liquid in pipes is the greatly increased transport rates of heat, mass, and momentum. In practical situations this enhancement can be a benefit or it can result in serious operational problems. For example, gas-liquid flow always results in substantially higher pressure drop and this is usually undesirable. However, much higher heat transfer coefficients can be expected and this can obviously be of benefit for purposes of design. Unfortunately, designers know so little of the behavior of such two phase systems and as a result these advantages are not utilized. Due to the complexity of the second order boundary model as well as the fact that the pressure variation across the film is small compared to the imposed gas phase pressure, the countercurrent gas flow affect was studied for the standard boundary layer model. A different stream function that can compensate the shear stress affect was developed and this stream function also can predict periodic solutions. The discretized model equations were transformed to a traveling wave coordinate system. A stability analysis of these sets of equations showed the presence of a Hopf bifurcation for certain values of the traveling wave velocity and the shear stress. The Hopf celerity was increased due to the countercurrent shear. For low flow rate the increases of celerity are more than for the high flow rate, which was also observed in experiments. Numerical integration of a traveling wave simplification of the model also predicts the existence of chaotic large amplitude, nonperiodic waves as observed in the experiments. The film thickness was increased by the shear.

Inertioelastic Flow Instability at a Stagnation Point

NASA Astrophysics Data System (ADS)

Burshtein, Noa; Zografos, Konstantinos; Shen, Amy Q.; Poole, Robert J.; Haward, Simon J.

2017-10-01

A number of important industrial applications exploit the ability of small quantities of high molecular weight polymer to suppress instabilities that arise in the equivalent flow of Newtonian fluids, a particular example being turbulent drag reduction. However, it can be extremely difficult to probe exactly how the polymer acts to, e.g., modify the streamwise near-wall eddies in a fully turbulent flow. Using a novel cross-slot flow configuration, we exploit a flow instability in order to create and study a single steady-state streamwise vortex. By quantitative experiment, we show how the addition of small quantities (parts per million) of a flexible polymer to a Newtonian solvent dramatically affects both the onset conditions for this instability and the subsequent growth of the axial vorticity. Complementary numerical simulations with a finitely extensible nonlinear elastic dumbbell model show that these modifications are due to the growth of polymeric stress within specific regions of the flow domain. Our data fill a significant gap in the literature between the previously reported purely inertial and purely elastic flow regimes and provide a link between the two by showing how the instability mode is transformed as the fluid elasticity is varied. Our results and novel methods are relevant to understanding the mechanisms underlying industrial uses of weakly elastic fluids and also to understanding inertioelastic instabilities in more confined flows through channels with intersections and stagnation points.

Assessment of Reynolds stress components and turbulent pressure loss using 4D flow MRI with extended motion encoding.

PubMed

Haraldsson, Henrik; Kefayati, Sarah; Ahn, Sinyeob; Dyverfeldt, Petter; Lantz, Jonas; Karlsson, Matts; Laub, Gerhard; Ebbers, Tino; Saloner, David

2018-04-01

To measure the Reynolds stress tensor using 4D flow MRI, and to evaluate its contribution to computed pressure maps. A method to assess both velocity and Reynolds stress using 4D flow MRI is presented and evaluated. The Reynolds stress is compared by cross-sectional integrals of the Reynolds stress invariants. Pressure maps are computed using the pressure Poisson equation-both including and neglecting the Reynolds stress. Good agreement is seen for Reynolds stress between computational fluid dynamics, simulated MRI, and MRI experiment. The Reynolds stress can significantly influence the computed pressure loss for simulated (eg, -0.52% vs -15.34% error; P < 0.001) and experimental (eg, 306 ± 11 vs 203 ± 6 Pa; P < 0.001) data. A 54% greater pressure loss is seen at the highest experimental flow rate when accounting for Reynolds stress (P < 0.001). 4D flow MRI with extended motion-encoding enables quantification of both the velocity and the Reynolds stress tensor. The additional information provided by this method improves the assessment of pressure gradients across a stenosis in the presence of turbulence. Unlike conventional methods, which are only valid if the flow is laminar, the proposed method is valid for both laminar and disturbed flow, a common presentation in diseased vessels. Magn Reson Med 79:1962-1971, 2018. © 2017 International Society for Magnetic Resonance in Medicine. © 2017 International Society for Magnetic Resonance in Medicine.

Human Cardiovascular Responses to Passive Heat Stress

PubMed Central

Crandall, Craig G.; Wilson, Thad E.

2016-01-01

Heat stress increases human morbidity and mortality compared to normothermic conditions. Many occupations, disease states, as well as stages of life are especially vulnerable to the stress imposed on the cardiovascular system during exposure to hot ambient conditions. This review focuses on the cardiovascular responses to heat stress that are necessary for heat dissipation. To accomplish this regulatory feat requires complex autonomic nervous system control of the heart and various vascular beds. For example, during heat stress cardiac output increases up to twofold, by increases in heart rate and an active maintenance of stroke volume via increases in inotropy in the presence of decreases in cardiac preload. Baroreflexes retain the ability to regulate blood pressure in many, but not all, heat stress conditions. Central hypovolemia is another cardiovascular challenge brought about by heat stress, which if added to a subsequent central volumetric stress, such as hemorrhage, can be problematic and potentially dangerous, as syncope and cardiovascular collapse may ensue. These combined stresses can compromise blood flow and oxygenation to important tissues such as the brain. It is notable that this compromised condition can occur at cardiac outputs that are adequate during normothermic conditions but are inadequate in heat because of the increased systemic vascular conductance associated with cutaneous vasodilation. Understanding the mechanisms within this complex regulatory system will allow for the development of treatment recommendations and countermeasures to reduce risks during the ever-increasing frequency of severe heat events that are predicted to occur. PMID:25589263

Application of mean wall shear stress boundary condition to complex turbulent flows using a wall-modeled large eddy simulation

NASA Astrophysics Data System (ADS)

Cho, Minjeong; Lee, Jungil; Choi, Haecheon

2012-11-01

The mean wall shear stress boundary condition was successfully applied to turbulent channel and boundary flows using large eddy simulation without resolving near-wall region (see Lee, Cho & Choi in this book of abstracts). In the present study, we apply this boundary condition to more complex flows where flow separation and redeveloping flow exist. As a test problem, we consider flow over a backward-facing step at Reh = 22860 based on the step height. Turbulent boundary layer flow at the inlet (Reθ = 1050) is obtained using inflow generation technique by Lund et al. (1998) but with wall shear stress boundary condition. First, we prescribe the mean wall shear stress distribution obtained from DNS (Kim, 2011, Ph.D. Thesis, Stanford U.) as the boundary condition of present simulation. Here we give no-slip boundary condition at flow-reversal region. The present results are in good agreements with the flow statistics by DNS. Currently, a dynamic approach of obtaining mean wall shear stress based on the log-law is being applied to the flow having flow separation and its results will be shown in the presentation. Supported by the WCU and NRF programs.

New concepts for Reynolds stress transport equation modeling of inhomogeneous flows

NASA Technical Reports Server (NTRS)

Perot, J. Blair; Moin, Parviz

1993-01-01

The ability to model turbulence near solid walls and other types of boundaries is important in predicting complex engineering flows. Most turbulence modeling has concentrated either on flows which are nearly homogeneous or isotropic, or on turbulent boundary layers. Boundary layer models usually rely very heavily on the presence of mean shear and the production of turbulence due to that mean shear. Most other turbulence models are based on the assumption of quasi-homogeneity. However, there are many situations of engineering interest which do not involve large shear rates and which are not quasi-homogeneous or isotropic. Shear-free turbulent boundary layers are the prototypical example of such flows, with practical situations being separation and reattachment, bluff body flow, high free-stream turbulence, and free surface flows. Although these situations are not as common as the variants of the flat plate turbulent boundary layer, they tend to be critical factors in complex engineering situations. The models developed are intended to extend classical quasi-homogeneous models into regions of large inhomogeneity. These models do not rely on the presence of mean shear or production, but are still applicable when those additional effects are included. Although the focus is on shear-free boundary layers as tests for these models, results for standard shearing boundary layers are also shown.

Upscaling the Navier-Stokes Equation for Turbulent Flows in Porous Media Using a Volume Averaging Method

NASA Astrophysics Data System (ADS)

Wood, Brian; He, Xiaoliang; Apte, Sourabh

2017-11-01

Turbulent flows through porous media are encountered in a number of natural and engineered systems. Many attempts to close the Navier-Stokes equation for such type of flow have been made, for example using RANS models and double averaging. On the other hand, Whitaker (1996) applied volume averaging theorem to close the macroscopic N-S equation for low Re flow. In this work, the volume averaging theory is extended into the turbulent flow regime to posit a relationship between the macroscale velocities and the spatial velocity statistics in terms of the spatial averaged velocity only. Rather than developing a Reynolds stress model, we propose a simple algebraic closure, consistent with generalized effective viscosity models (Pope 1975), to represent the spatial fluctuating velocity and pressure respectively. The coefficients (one 1st order, two 2nd order and one 3rd order tensor) of the linear functions depend on averaged velocity and gradient. With the data set from DNS, performed with inertial and turbulent flows (pore Re of 300, 500 and 1000) through a periodic face centered cubic (FCC) unit cell, all the unknown coefficients can be computed and the closure is complete. The macroscopic quantity calculated from the averaging is then compared with DNS data to verify the upscaling. NSF Project Numbers 1336983, 1133363.

A level-set method for two-phase flows with moving contact line and insoluble surfactant

NASA Astrophysics Data System (ADS)

Xu, Jian-Jun; Ren, Weiqing

2014-04-01

A level-set method for two-phase flows with moving contact line and insoluble surfactant is presented. The mathematical model consists of the Navier-Stokes equation for the flow field, a convection-diffusion equation for the surfactant concentration, together with the Navier boundary condition and a condition for the dynamic contact angle derived by Ren et al. (2010) [37]. The numerical method is based on the level-set continuum surface force method for two-phase flows with surfactant developed by Xu et al. (2012) [54] with some cautious treatment for the boundary conditions. The numerical method consists of three components: a flow solver for the velocity field, a solver for the surfactant concentration, and a solver for the level-set function. In the flow solver, the surface force is dealt with using the continuum surface force model. The unbalanced Young stress at the moving contact line is incorporated into the Navier boundary condition. A convergence study of the numerical method and a parametric study are presented. The influence of surfactant on the dynamics of the moving contact line is illustrated using examples. The capability of the level-set method to handle complex geometries is demonstrated by simulating a pendant drop detaching from a wall under gravity.

Paper recycling framework, the "Wheel of Fiber".

PubMed

Ervasti, Ilpo; Miranda, Ruben; Kauranen, Ilkka

2016-06-01

At present, there is no reliable method in use that unequivocally describes paper industry material flows and makes it possible to compare geographical regions with each other. A functioning paper industry Material Flow Account (MFA) that uses uniform terminology and standard definitions for terms and structures is necessary. Many of the presently used general level MFAs, which are called frameworks in this article, stress the importance of input and output flows but do not provide a uniform picture of material recycling. Paper industry is an example of a field in which recycling plays a key role. Additionally, terms related to paper industry recycling, such as collection rate, recycling rate, and utilization rate, are not defined uniformly across regions and time. Thus, reliably comparing material recycling activity between geographical regions or calculating any regional summaries is difficult or even impossible. The objective of this study is to give a partial solution to the problem of not having a reliable method in use that unequivocally describes paper industry material flows. This is done by introducing a new material flow framework for paper industry in which the flow and stage structure supports the use of uniform definitions for terms related to paper recycling. This new framework is termed the Detailed Wheel of Fiber. Copyright © 2016 Elsevier Ltd. All rights reserved.

Anisotropic shear stress patterns predict the orientation of convergent tissue movements in the embryonic heart

PubMed Central

2017-01-01

Myocardial contractility and blood flow provide essential mechanical cues for the morphogenesis of the heart. In general, endothelial cells change their migratory behavior in response to shear stress patterns, according to flow directionality. Here, we assessed the impact of shear stress patterns and flow directionality on the behavior of endocardial cells, the specialized endothelial cells of the heart. At the early stages of zebrafish heart valve formation, we show that endocardial cells are converging to the valve-forming area and that this behavior depends upon mechanical forces. Quantitative live imaging and mathematical modeling allow us to correlate this tissue convergence with the underlying flow forces. We predict that tissue convergence is associated with the direction of the mean wall shear stress and of the gradient of harmonic phase-averaged shear stresses, which surprisingly do not match the overall direction of the flow. This contrasts with the usual role of flow directionality in vascular development and suggests that the full spatial and temporal complexity of the wall shear stress should be taken into account when studying endothelial cell responses to flow in vivo. PMID:29183943

Prediction of Transonic Vortex Flows Using Linear and Nonlinear Turbulent Eddy Viscosity Models

NASA Technical Reports Server (NTRS)

Bartels, Robert E.; Gatski, Thomas B.

2000-01-01

Three-dimensional transonic flow over a delta wing is investigated with a focus on the effect of transition and influence of turbulence stress anisotropies. The performance of linear eddy viscosity models and an explicit algebraic stress model is assessed at the start of vortex flow, and the results compared with experimental data. To assess the effect of transition location, computations that either fix transition or are fully turbulent are performed. To assess the effect of the turbulent stress anisotropy, comparisons are made between predictions from the algebraic stress model and the linear eddy viscosity models. Both transition location and turbulent stress anisotropy significantly affect the 3D flow field. The most significant effect is found to be the modeling of transition location. At a Mach number of 0.90, the computed solution changes character from steady to unsteady depending on transition onset. Accounting for the anisotropies in the turbulent stresses also considerably impacts the flow, most notably in the outboard region of flow separation.

PIV Measurement of Wall Shear Stress and Flow Structures within an Intracranial Aneurysm Model

NASA Astrophysics Data System (ADS)

Chow, Ricky; Sparrow, Eph; Campbell, Gary; Divani, Afshin; Sheng, Jian

2012-11-01

The formation and rupture of an intracranial aneurysm (IA) is a debilitating and often lethal event. Geometric features of the aneurysm bulb and upstream artery, such as bulb size, bulb shape, and curvature of the artery, are two groups of factors that define the flow and stresses within an IA. Abnormal flow stresses are related to rupture. This presentation discusses the development of a quasi-3D PIV technique and its application in various glass models at Re = 275 and 550 to experimentally assess at a preliminary level the impact of geometry and flow rate. Some conclusions are to be drawn linking geometry of the flow domain to rupture risk. The extracted results also serve as the baseline case and as a precursor to a companion presentation by the authors discussing the impact of flow diverters, a new class of medical devices. The PIV experiments were performed in a fully index-matched flow facility, allowing for unobstructed observations over complex geometry. A reconstruction and analysis method was devised to obtain 3D mean wall stress distributions and flow fields. The quasi 3D measurements were reconstructed from orthogonal planes encompassing the entire glass model, spaced 0.4mm apart. Wall shear stresses were evaluated from the near-wall flow viscous stresses.

Ursodeoxycholic Acid (UDCA) Exerts Anti-Atherogenic Effects by Inhibiting Endoplasmic Reticulum (ER) Stress Induced by Disturbed Flow.

PubMed

Chung, Jihwa; Kim, Kyoung Hwa; Lee, Seok Cheol; An, Shung Hyun; Kwon, Kihwan

2015-10-01

Disturbed blood flow with low-oscillatory shear stress (OSS) is a predominant atherogenic factor leading to dysfunctional endothelial cells (ECs). Recently, it was found that disturbed flow can directly induce endoplasmic reticulum (ER) stress in ECs, thereby playing a critical role in the development and progression of atherosclerosis. Ursodeoxycholic acid (UDCA), a naturally occurring bile acid, has long been used to treat chronic cholestatic liver disease and is known to alleviate endoplasmic reticulum (ER) stress at the cellular level. However, its role in atherosclerosis remains unexplored. In this study, we demonstrated the anti-atherogenic activity of UDCA via inhibition of disturbed flow-induced ER stress in atherosclerosis. UDCA effectively reduced ER stress, resulting in a reduction in expression of X-box binding protein-1 (XBP-1) and CEBP-homologous protein (CHOP) in ECs. UDCA also inhibits the disturbed flow-induced inflammatory responses such as increases in adhesion molecules, monocyte adhesion to ECs, and apoptosis of ECs. In a mouse model of disturbed flow-induced atherosclerosis, UDCA inhibits atheromatous plaque formation through the alleviation of ER stress and a decrease in adhesion molecules. Taken together, our results revealed that UDCA exerts anti-atherogenic activity in disturbed flow-induced atherosclerosis by inhibiting ER stress and the inflammatory response. This study suggests that UDCA may be a therapeutic agent for prevention or treatment of atherosclerosis.

Filament turnover tunes both force generation and dissipation to control long-range flows in a model actomyosin cortex

PubMed Central

McCall, Patrick M.; Gardel, Margaret L.; Munro, Edwin M.

2017-01-01

Actomyosin-based cortical flow is a fundamental engine for cellular morphogenesis. Cortical flows are generated by cross-linked networks of actin filaments and myosin motors, in which active stress produced by motor activity is opposed by passive resistance to network deformation. Continuous flow requires local remodeling through crosslink unbinding and and/or filament disassembly. But how local remodeling tunes stress production and dissipation, and how this in turn shapes long range flow, remains poorly understood. Here, we study a computational model for a cross-linked network with active motors based on minimal requirements for production and dissipation of contractile stress: Asymmetric filament compliance, spatial heterogeneity of motor activity, reversible cross-links and filament turnover. We characterize how the production and dissipation of network stress depend, individually, on cross-link dynamics and filament turnover, and how these dependencies combine to determine overall rates of cortical flow. Our analysis predicts that filament turnover is required to maintain active stress against external resistance and steady state flow in response to external stress. Steady state stress increases with filament lifetime up to a characteristic time τm, then decreases with lifetime above τm. Effective viscosity increases with filament lifetime up to a characteristic time τc, and then becomes independent of filament lifetime and sharply dependent on crosslink dynamics. These individual dependencies of active stress and effective viscosity define multiple regimes of steady state flow. In particular our model predicts that when filament lifetimes are shorter than both τc and τm, the dependencies of effective viscosity and steady state stress on filament turnover cancel one another, such that flow speed is insensitive to filament turnover, and shows a simple dependence on motor activity and crosslink dynamics. These results provide a framework for understanding how animal cells tune cortical flow through local control of network remodeling. PMID:29253848

The dependence of permeability on effective stress from flow tests at hot dry rock reservoirs at Rosemanowes (Cornwall) and Fenton Hill (New Mexico)

USGS Publications Warehouse

Nathenson, M.

1999-01-01

Effective stress is the primary control on permeability and thus on flow and water loss for two-well hot dry rock systems involving injection and production that have been tested to date. Theoretical relations are derived for the flow between an injector and producer, including the dependence of permeability on effective stress. Four relations for permeability as a function of effective stress are used to match field data for the hot dry rock systems at Rosemanowes, Cornwall, and Fenton Hill, New Mexico. The flow and water loss behavior of these systems are well explained by the influence of effective stress on permeability. All four relations for permeability as a function of effective stress are successful in matching the field data, but some have difficulty in determining unique values for elastic and hydrologic parameters.Effective stress is the primary control on permeability and thus on flow and water loss for two-well hot dry rock systems involving injection and production that have been tested to date. Theoretical relations are derived for the flow between an injector and producer, including the dependence of permeability on effective stress. Four relations for permeability as a function of effective stress are used to match field data for the hot dry rock systems at Rosemanowes, Cornwall, and Fenton Hill, New Mexico. The flow and water loss behavior of these systems are well explained by the influence of effective stress on permeability. All four relations for permeability as a function of effective stress are successful in matching the field data, but some have difficulty in determining unique values for elastic and hydrologic parameters.

Cool-down flow-rate limits imposed by thermal stresses in LNG pipelines

NASA Astrophysics Data System (ADS)

Novak, J. K.; Edeskuty, F. J.; Bartlit, J. R.

Warm cryogenic pipelines are usually cooled to operating temperature by a small, steady flow of the liquid cryogen. If this flow rate is too high or too low, undesirable stresses will be produced. Low flow-rate limits based on avoidance of stratified two-phase flow were calculated for pipelines cooled with liquid hydrogen or nitrogen. High flow-rate limits for stainless steel and aluminum pipelines cooled by liquid hydrogen or nitrogen were determined by calculating thermal stress in thick components vs flow rate and then selecting some reasonable stress limits. The present work extends these calculations to pipelines made of AISI 304 stainless steel, 6061 aluminum, or ASTM A420 9% nickel steel cooled by liquid methane or a typical natural gas. Results indicate that aluminum and 9% nickel steel components can tolerate very high cool-down flow rates, based on not exceeding the material yield strength.

Thermal elastoplastic structural analysis of non-metallic thermal protection systems

NASA Technical Reports Server (NTRS)

Chung, T. J.; Yagawa, G.

1972-01-01

An incremental theory and numerical procedure to analyze a three-dimensional thermoelastoplastic structure subjected to high temperature, surface heat flux, and volume heat supply as well as mechanical loadings are presented. Heat conduction equations and equilibrium equations are derived by assuming a specific form of incremental free energy, entropy, stresses and heat flux together with the first and second laws of thermodynamics, von Mises yield criteria and Prandtl-Reuss flow rule. The finite element discretization using the linear isotropic three-dimensional element for the space domain and a difference operator corresponding to a linear variation of temperature within a small time increment for the time domain lead to systematic solutions of temperature distribution and displacement and stress fields. Various boundary conditions such as insulated surfaces and convection through uninsulated surface can be easily treated. To demonstrate effectiveness of the present formulation a number of example problems are presented.

Low-frequency seismic events in a wider volcanological context

NASA Astrophysics Data System (ADS)

Neuberg, J. W.; Collombet, M.

2006-12-01

Low-frequency seismic events have been in the centre of attention for several years, particularly on volcanoes with highly viscous magmas. The ultimate aim is to detect changes in volcanic activity by identifying changes in the seismic behaviour in order to forecast an eruption, or in case of an ongoing eruption, forecast the short and longterm behaviour of the volcanic system. A major boost in recent years arose through several attempts of multi-parameter volcanic monitoring and modelling programs, which allowed multi-disciplinary groups of volcanologists to interpret seismic signals together with, e.g. ground deformation, stress field analysis and petrological information. This talk will give several examples of such multi-disciplinary projects, focussing on the joint modelling of seismic source processes for low-frequency events together with advanced magma flow models, and the signs of magma movement in the deformation and stress field at the surface.

A unified momentum equation approach for computing thermal residual stresses during melting and solidification

NASA Astrophysics Data System (ADS)

Yeo, Haram; Ki, Hyungson

2018-03-01

In this article, we present a novel numerical method for computing thermal residual stresses from a viewpoint of fluid-structure interaction (FSI). In a thermal processing of a material, residual stresses are developed as the material undergoes melting and solidification, and liquid, solid, and a mixture of liquid and solid (or mushy state) coexist and interact with each other during the process. In order to accurately account for the stress development during phase changes, we derived a unified momentum equation from the momentum equations of incompressible fluids and elastoplastic solids. In this approach, the whole fluid-structure system is treated as a single continuum, and the interaction between fluid and solid phases across the mushy zone is naturally taken into account in a monolithic way. For thermal analysis, an enthalpy-based method was employed. As a numerical example, a two-dimensional laser heating problem was considered, where a carbon steel sheet was heated by a Gaussian laser beam. Momentum and energy equations were discretized on a uniform Cartesian grid in a finite volume framework, and temperature-dependent material properties were used. The austenite-martensite phase transformation of carbon steel was also considered. In this study, the effects of solid strains, fluid flow, mushy zone size, and laser heating time on residual stress formation were investigated.

Microbial stress-response physiology and its implications for ecosystem function.

PubMed

Schimel, Joshua; Balser, Teri C; Wallenstein, Matthew

2007-06-01

Microorganisms have a variety of evolutionary adaptations and physiological acclimation mechanisms that allow them to survive and remain active in the face of environmental stress. Physiological responses to stress have costs at the organismal level that can result in altered ecosystem-level C, energy, and nutrient flows. These large-scale impacts result from direct effects on active microbes' physiology and by controlling the composition of the active microbial community. We first consider some general aspects of how microbes experience environmental stresses and how they respond to them. We then discuss the impacts of two important ecosystem-level stressors, drought and freezing, on microbial physiology and community composition. Even when microbial community response to stress is limited, the physiological costs imposed on soil microbes are large enough that they may cause large shifts in the allocation and fate of C and N. For example, for microbes to synthesize the osmolytes they need to survive a single drought episode they may consume up to 5% of total annual net primary production in grassland ecosystems, while acclimating to freezing conditions switches Arctic tundra soils from immobilizing N during the growing season to mineralizing it during the winter. We suggest that more effectively integrating microbial ecology into ecosystem ecology will require a more complete integration of microbial physiological ecology, population biology, and process ecology.

The constructal law of design and evolution in nature

PubMed Central

Bejan, Adrian; Lorente, Sylvie

2010-01-01

Constructal theory is the view that (i) the generation of images of design (pattern, rhythm) in nature is a phenomenon of physics and (ii) this phenomenon is covered by a principle (the constructal law): ‘for a finite-size flow system to persist in time (to live) it must evolve such that it provides greater and greater access to the currents that flow through it’. This law is about the necessity of design to occur, and about the time direction of the phenomenon: the tape of the design evolution ‘movie’ runs such that existing configurations are replaced by globally easier flowing configurations. The constructal law has two useful sides: the prediction of natural phenomena and the strategic engineering of novel architectures, based on the constructal law, i.e. not by mimicking nature. We show that the emergence of scaling laws in inanimate (geophysical) flow systems is the same phenomenon as the emergence of allometric laws in animate (biological) flow systems. Examples are lung design, animal locomotion, vegetation, river basins, turbulent flow structure, self-lubrication and natural multi-scale porous media. This article outlines the place of the constructal law as a self-standing law in physics, which covers all the ad hoc (and contradictory) statements of optimality such as minimum entropy generation, maximum entropy generation, minimum flow resistance, maximum flow resistance, minimum time, minimum weight, uniform maximum stresses and characteristic organ sizes. Nature is configured to flow and move as a conglomerate of ‘engine and brake’ designs. PMID:20368252

The constructal law of design and evolution in nature.

PubMed

Bejan, Adrian; Lorente, Sylvie

2010-05-12

Constructal theory is the view that (i) the generation of images of design (pattern, rhythm) in nature is a phenomenon of physics and (ii) this phenomenon is covered by a principle (the constructal law): 'for a finite-size flow system to persist in time (to live) it must evolve such that it provides greater and greater access to the currents that flow through it'. This law is about the necessity of design to occur, and about the time direction of the phenomenon: the tape of the design evolution 'movie' runs such that existing configurations are replaced by globally easier flowing configurations. The constructal law has two useful sides: the prediction of natural phenomena and the strategic engineering of novel architectures, based on the constructal law, i.e. not by mimicking nature. We show that the emergence of scaling laws in inanimate (geophysical) flow systems is the same phenomenon as the emergence of allometric laws in animate (biological) flow systems. Examples are lung design, animal locomotion, vegetation, river basins, turbulent flow structure, self-lubrication and natural multi-scale porous media. This article outlines the place of the constructal law as a self-standing law in physics, which covers all the ad hoc (and contradictory) statements of optimality such as minimum entropy generation, maximum entropy generation, minimum flow resistance, maximum flow resistance, minimum time, minimum weight, uniform maximum stresses and characteristic organ sizes. Nature is configured to flow and move as a conglomerate of 'engine and brake' designs.

Hot Deformation Behavior and a Two-Stage Constitutive Model of 20Mn5 Solid Steel Ingot during Hot Compression

PubMed Central

Liu, Min; Ma, Qing-Xian; Luo, Jian-Bin

2018-01-01

20Mn5 steel is widely used in the manufacture of heavy hydro-generator shaft forging due to its strength, toughness, and wear resistance. However, the hot deformation and recrystallization behaviors of 20Mn5 steel compressed under a high temperature were not studied. For this article, hot compression experiments under temperatures of 850–1200 °C and strain rates of 0.01 s−1–1 s−1 were conducted using a Gleeble-1500D thermo-mechanical simulator. Flow stress-strain curves and microstructure after hot compression were obtained. Effects of temperature and strain rate on microstructure are analyzed. Based on the classical stress-dislocation relationship and the kinetics of dynamic recrystallization, a two-stage constitutive model is developed to predict the flow stress of 20Mn5 steel. Comparisons between experimental flow stress and predicted flow stress show that the predicted flow stress values are in good agreement with the experimental flow stress values, which indicates that the proposed constitutive model is reliable and can be used for numerical simulation of hot forging of 20Mn5 solid steel ingot. PMID:29547570

Elimination of numerical diffusion in 1 - phase and 2 - phase flows

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rajamaeki, M.

1997-07-01

The new hydraulics solution method PLIM (Piecewise Linear Interpolation Method) is capable of avoiding the excessive errors, numerical diffusion and also numerical dispersion. The hydraulics solver CFDPLIM uses PLIM and solves the time-dependent one-dimensional flow equations in network geometry. An example is given for 1-phase flow in the case when thermal-hydraulics and reactor kinetics are strongly coupled. Another example concerns oscillations in 2-phase flow. Both the example computations are not possible with conventional methods.

The many impacts of building mountain belts on plate tectonics and mantle flow

NASA Astrophysics Data System (ADS)

Yamato, Philippe; Husson, Laurent

2015-04-01

During the Cenozoic, the number of orogens on Earth increased. This observation readily indicates that in the same time, compression in the lithosphere became gradually more and more important. Such an increase of stresses in the lithosphere can impact on plate tectonics and mantle dynamics. We show that mountain belts at plate boundaries increasingly obstruct plate tectonics, slowing down and reorienting their motions. In turn, this changes the dynamic and kinematic surface conditions of the underlying flowing mantle. Ultimately, this modifies the pattern of mantle flow. This forcing could explain many first order features of Cenozoic plate tectonics and mantle flow. Among these, one can cite the compression of passive margins, the important variations in the rates of spreading at oceanic ridges, or the initiation of subduction, the onset of obduction, for the lithosphere. In the mantle, such change in boundary condition redesigns the pattern of mantle flow and, consequently, the oceanic lithosphere cooling. In order to test this hypothesis we first present thermo-mechanical numerical models of mantle convection above which a lithosphere rests. Our results show that when collision occurs, the mantle flow is highly modified, which leads to (i) increasing shear stresses below the lithosphere and (ii) to a modification of the convection style. In turn, the transition between a 'free' convection (mobile lid) and an 'upset' convection (stagnant -or sluggish- lid) highly impacts the dynamics of the lithosphere at the surface of the Earth. Thereby, on the basis of these models and a variety of real examples, we show that on the other side of a collision zone, passive margins become squeezed and can undergo compression, which may ultimately evolve into subduction or obduction. We also show that much further, due to the blocking of the lithosphere, spreading rates decrease at the ridge, a fact that may explain a variety of features such as the low magmatism of ultraslow spreading ridges or the departure of slow spreading ridges from the half-space cooling model.

Review of critical flow rate, propagation of pressure pulse, and sonic velocity in two-phase media

NASA Technical Reports Server (NTRS)

Hsu, Y.

1972-01-01

For single-phase media, the critical discharge velocity, the sonic velocity, and the pressure pulse propagation velocity can be expressed in the same form by assuming isentropic, equilibria processes. In two-phase mixtures, the same concept is not valid due to the existence of interfacial transports of momentum, heat, and mass. Thus, the three velocities should be treated differently and separately for each particular condition, taking into account the various transport processes involved under that condition. Various attempts are reviewed to predict the critical discharge rate or the propagation velocities by considering slip ratio (momentum change), evaporation (mass and heat transport), flow pattern, etc. Experimental data were compared with predictions based on various theorems. The importance is stressed of the time required to achieve equilibrium as compared with the time available during the process, for example, of passing a pressure pulse.

A project management system for the X-29A flight test program

NASA Technical Reports Server (NTRS)

Stewart, J. F.; Bauer, C. A.

1983-01-01

The project-management system developed for NASA's participation in the X-29A aircraft development program is characterized from a theoretical perspective, as an example of a system appropriate to advanced, highly integrated technology projects. System-control theory is applied to the analysis of classical project-management techniques and structures, which are found to be of closed-loop multivariable type; and the effects of increasing project complexity and integration are evaluated. The importance of information flow, sampling frequency, information holding, and delays is stressed. The X-29A system is developed in four stages: establishment of overall objectives and requirements, determination of information processes (block diagrams) definition of personnel functional roles and relationships, and development of a detailed work-breakdown structure. The resulting system is shown to require a greater information flow to management than conventional methods. Sample block diagrams are provided.

Mechanical Control of Tissue Morphogenesis

PubMed Central

Patwari, Parth; Lee, Richard T.

2008-01-01

Mechanical forces participate in morphogenesis from the level of individual cells to whole organism patterning. This manuscript reviews recent research that has identified specific roles for mechanical forces in important developmental events. One well-defined example is that dynein-driven cilia create fluid flow that determines left-right patterning in the early mammalian embryo. Fluid flow is also important for vasculogenesis, and evidence suggests that fluid shear stress rather than fluid transport is primarily required for remodeling the early vasculature. Contraction of the actin cytoskeleton, driven by nonmuscle myosins and regulated by the Rho family GTPases, is a recurring mechanism for controlling morphogenesis throughout development, from gastrulation to cardiogenesis. Finally, novel experimental approaches suggest critical roles for the actin cytoskeleton and the mechanical environment in determining differentiation of mesenchymal stem cells. Insights into the mechanisms linking mechanical forces to cell and tissue differentiation pathways are important for understanding many congenital diseases and for developing regenerative medicine strategies. PMID:18669930

Asymmetric three-dimensional topography over mantle plumes.

PubMed

Burov, Evgueni; Gerya, Taras

2014-09-04

The role of mantle-lithosphere interactions in shaping surface topography has long been debated. In general, it is supposed that mantle plumes and vertical mantle flows result in axisymmetric, long-wavelength topography, which strongly differs from the generally asymmetric short-wavelength topography created by intraplate tectonic forces. However, identification of mantle-induced topography is difficult, especially in the continents. It can be argued therefore that complex brittle-ductile rheology and stratification of the continental lithosphere result in short-wavelength modulation and localization of deformation induced by mantle flow. This deformation should also be affected by far-field stresses and, hence, interplay with the 'tectonic' topography (for example, in the 'active/passive' rifting scenario). Testing these ideas requires fully coupled three-dimensional numerical modelling of mantle-lithosphere interactions, which so far has not been possible owing to the conceptual and technical limitations of earlier approaches. Here we present new, ultra-high-resolution, three-dimensional numerical experiments on topography over mantle plumes, incorporating a weakly pre-stressed (ultra-slow spreading), rheologically realistic lithosphere. The results show complex surface evolution, which is very different from the smooth, radially symmetric patterns usually assumed as the canonical surface signature of mantle upwellings. In particular, the topography exhibits strongly asymmetric, small-scale, three-dimensional features, which include narrow and wide rifts, flexural flank uplifts and fault structures. This suggests a dominant role for continental rheological structure and intra-plate stresses in controlling dynamic topography, mantle-lithosphere interactions, and continental break-up processes above mantle plumes.

Research on wall shear stress considering wall roughness when shear swirling flow vibration cementing

NASA Astrophysics Data System (ADS)

Cui, Zhihua; Ai, Chi; Feng, Fuping

2017-01-01

When shear swirling flow vibration cementing, the casing is revolving periodically and eccentrically, which leads to the annulus fluid in turbulent swirling flow state. The wall shear stress is more than that in laminar flow field when conventional cementing. The paper mainly studied the wall shear stress distribution on the borehole wall when shear swirling flow vibration cementing based on the finite volume method. At the same time, the wall roughness affected and changed the turbulent flow near the borehole wall and the wall shear stress. Based on the wall function method, the paper established boundary conditions considering the wall roughness and derived the formula of the wall shear stress. The results showed that the wall roughness significantly increases the wall shear stress. However, the larger the wall roughness, the greater the thickness of mud cake, which weakening the cementing strength. Considering the effects in a comprehensive way, it is discovered that the particle size of solid phase in drilling fluid is about 0.1 mm to get better cementing quality.

Temperature and blood flow distribution in the human leg during passive heat stress.

PubMed

Chiesa, Scott T; Trangmar, Steven J; González-Alonso, José

2016-05-01

The influence of temperature on the hemodynamic adjustments to direct passive heat stress within the leg's major arterial and venous vessels and compartments remains unclear. Fifteen healthy young males were tested during exposure to either passive whole body heat stress to levels approaching thermal tolerance [core temperature (Tc) + 2°C; study 1; n = 8] or single leg heat stress (Tc + 0°C; study 2; n = 7). Whole body heat stress increased perfusion and decreased oscillatory shear index in relation to the rise in leg temperature (Tleg) in all three major arteries supplying the leg, plateauing in the common and superficial femoral arteries before reaching severe heat stress levels. Isolated leg heat stress increased arterial blood flows and shear patterns to a level similar to that obtained during moderate core hyperthermia (Tc + 1°C). Despite modest increases in great saphenous venous (GSV) blood flow (0.2 l/min), the deep venous system accounted for the majority of returning flow (common femoral vein 0.7 l/min) during intense to severe levels of heat stress. Rapid cooling of a single leg during severe whole body heat stress resulted in an equivalent blood flow reduction in the major artery supplying the thigh deep tissues only, suggesting central temperature-sensitive mechanisms contribute to skin blood flow alone. These findings further our knowledge of leg hemodynamic responses during direct heat stress and provide evidence of potentially beneficial vascular alterations during isolated limb heat stress that are equivalent to those experienced during exposure to moderate levels of whole body hyperthermia. Copyright © 2016 the American Physiological Society.

Temperature and blood flow distribution in the human leg during passive heat stress

PubMed Central

Chiesa, Scott T.; Trangmar, Steven J.

2016-01-01

The influence of temperature on the hemodynamic adjustments to direct passive heat stress within the leg's major arterial and venous vessels and compartments remains unclear. Fifteen healthy young males were tested during exposure to either passive whole body heat stress to levels approaching thermal tolerance [core temperature (Tc) + 2°C; study 1; n = 8] or single leg heat stress (Tc + 0°C; study 2; n = 7). Whole body heat stress increased perfusion and decreased oscillatory shear index in relation to the rise in leg temperature (Tleg) in all three major arteries supplying the leg, plateauing in the common and superficial femoral arteries before reaching severe heat stress levels. Isolated leg heat stress increased arterial blood flows and shear patterns to a level similar to that obtained during moderate core hyperthermia (Tc + 1°C). Despite modest increases in great saphenous venous (GSV) blood flow (0.2 l/min), the deep venous system accounted for the majority of returning flow (common femoral vein 0.7 l/min) during intense to severe levels of heat stress. Rapid cooling of a single leg during severe whole body heat stress resulted in an equivalent blood flow reduction in the major artery supplying the thigh deep tissues only, suggesting central temperature-sensitive mechanisms contribute to skin blood flow alone. These findings further our knowledge of leg hemodynamic responses during direct heat stress and provide evidence of potentially beneficial vascular alterations during isolated limb heat stress that are equivalent to those experienced during exposure to moderate levels of whole body hyperthermia. PMID:26823344

A Parallel-Plate Flow Chamber for Mechanical Characterization of Endothelial Cells Exposed to Laminar Shear Stress

PubMed Central

Wong, Andrew K.; LLanos, Pierre; Boroda, Nickolas; Rosenberg, Seth R.; Rabbany, Sina Y.

2017-01-01

Shear stresses induced by laminar fluid flow are essential to properly recapitulate the physiological microenvironment experienced by endothelial cells (ECs). ECs respond to these stresses via mechanotransduction by modulating their phenotype and biomechanical characteristics, which can be characterized by Atomic Force Microscopy (AFM). Parallel Plate Flow Chambers (PPFCs) apply unidirectional laminar fluid flow to EC monolayers in vitro. Since ECs in sealed PPFCs are inaccessible to AFM probes, cone-and-plate viscometers (CPs) are commonly used to apply shear stress. This paper presents a comparison of the efficacies of both methods. Computational Fluid Dynamic simulation and validation testing using EC responses as a metric have indicated limitations in the use of CPs to apply laminar shear stress. Monolayers subjected to laminar fluid flow in a PPFC respond by increasing cortical stiffness, elongating, and aligning filamentous actin in the direction of fluid flow to a greater extent than CP devices. Limitations using CP devices to provide laminar flow across an EC monolayer suggest they are better suited when studying EC response for disturbed flow conditions. PPFC platforms allow for exposure of ECs to laminar fluid flow conditions, recapitulating cellular biomechanical behaviors, whereas CP platforms allow for mechanical characterization of ECs under secondary flow. PMID:28989541

On explicit algebraic stress models for complex turbulent flows

NASA Technical Reports Server (NTRS)

Gatski, T. B.; Speziale, C. G.

1992-01-01

Explicit algebraic stress models that are valid for three-dimensional turbulent flows in noninertial frames are systematically derived from a hierarchy of second-order closure models. This represents a generalization of the model derived by Pope who based his analysis on the Launder, Reece, and Rodi model restricted to two-dimensional turbulent flows in an inertial frame. The relationship between the new models and traditional algebraic stress models -- as well as anistropic eddy visosity models -- is theoretically established. The need for regularization is demonstrated in an effort to explain why traditional algebraic stress models have failed in complex flows. It is also shown that these explicit algebraic stress models can shed new light on what second-order closure models predict for the equilibrium states of homogeneous turbulent flows and can serve as a useful alternative in practical computations.

Effect of stress, anxiety and depression on unstimulated salivary flow rate and xerostomia.

PubMed

Gholami, Neda; Hosseini Sabzvari, Behrous; Razzaghi, Alireza; Salah, Shilan

2017-01-01

Background. Unstimulated salivary flow rate can be influenced by different factors. This study was undertaken to evaluate the effect of stress, anxiety and depression on unstimulated salivary flow rate in adults. Methods. A total of 247 adult subjects, randomly selected from patients referring to Zanjan Dental School, were included in this investigation. The study procedures consisted of collecting salivary samples (in 5 minutes), completing a form for feeling of xerostomia and completing Depression Anxiety Stress Scale (DASS) Questionnaire to assess the severity of stress, anxiety and depression. Based on the results, the patients were categorized in four groups: Low salivary flow rate plus xerostomia (group 1, n=60), normal salivary flow rate plus xerostomia (group 2, n=59), low salivary flow rate without xerostomia (group 3, n=60) and normal salivary flow rate without xerostomia (control group, n=68). Results. The frequencies of subjects with severe and major depression in groups 1, 2 and 3 were 31.4%, 11.7% and 8.5%, respectively, with 4.4% in the control group. The frequencies of subjects with severe stress in groups 1, 2 and 3 were 21.7%, 3.3% and 11.9%, respectively, with 1.5% in the control group. The frequencies of patients with severe anxiety in groups 1, 2 and 3 were 50%, 30% and 61.1%, respectively, with 4.4% in the control group. Stress, anxiety and depression exhibited a statistically significant relationship with unstimulated salivary flow rate and xerostomia (P<0.05). Conclusion. Stress, anxiety and depression can influence unstimulated salivary flow rate and lead to xerostomia.

Hemodynamics model of fluid–solid interaction in internal carotid artery aneurysms

PubMed Central

Fu-Yu, Wang; Lei, Liu; Xiao-Jun, Zhang; Hai-Yue, Ju

2010-01-01

The objective of this study is to present a relatively simple method to reconstruct cerebral aneurysms as 3D numerical grids. The method accurately duplicates the geometry to provide computer simulations of the blood flow. Initial images were obtained by using CT angiography and 3D digital subtraction angiography in DICOM format. The image was processed by using MIMICS software, and the 3D fluid model (blood flow) and 3D solid model (wall) were generated. The subsequent output was exported to the ANSYS workbench software to generate the volumetric mesh for further hemodynamic study. The fluid model was defined and simulated in CFX software while the solid model was calculated in ANSYS software. The force data calculated firstly in the CFX software were transferred to the ANSYS software, and after receiving the force data, total mesh displacement data were calculated in the ANSYS software. Then, the mesh displacement data were transferred back to the CFX software. The data exchange was processed in workbench software. The results of simulation could be visualized in CFX-post. Two examples of grid reconstruction and blood flow simulation for patients with internal carotid artery aneurysms were presented. The wall shear stress, wall total pressure, and von Mises stress could be visualized. This method seems to be relatively simple and suitable for direct use by neurosurgeons or neuroradiologists, and maybe a practical tool for planning treatment and follow-up of patients after neurosurgical or endovascular interventions with 3D angiography. PMID:20812022

Hemodynamics model of fluid-solid interaction in internal carotid artery aneurysms.

PubMed

Bai-Nan, Xu; Fu-Yu, Wang; Lei, Liu; Xiao-Jun, Zhang; Hai-Yue, Ju

2011-01-01

The objective of this study is to present a relatively simple method to reconstruct cerebral aneurysms as 3D numerical grids. The method accurately duplicates the geometry to provide computer simulations of the blood flow. Initial images were obtained by using CT angiography and 3D digital subtraction angiography in DICOM format. The image was processed by using MIMICS software, and the 3D fluid model (blood flow) and 3D solid model (wall) were generated. The subsequent output was exported to the ANSYS workbench software to generate the volumetric mesh for further hemodynamic study. The fluid model was defined and simulated in CFX software while the solid model was calculated in ANSYS software. The force data calculated firstly in the CFX software were transferred to the ANSYS software, and after receiving the force data, total mesh displacement data were calculated in the ANSYS software. Then, the mesh displacement data were transferred back to the CFX software. The data exchange was processed in workbench software. The results of simulation could be visualized in CFX-post. Two examples of grid reconstruction and blood flow simulation for patients with internal carotid artery aneurysms were presented. The wall shear stress, wall total pressure, and von Mises stress could be visualized. This method seems to be relatively simple and suitable for direct use by neurosurgeons or neuroradiologists, and maybe a practical tool for planning treatment and follow-up of patients after neurosurgical or endovascular interventions with 3D angiography.

Procedures for characterizing an alloy and predicting cyclic life with the total strain version of Strainrange Partitioning

NASA Technical Reports Server (NTRS)

Saltsman, James F.; Halford, Gary R.

1989-01-01

Procedures are presented for characterizing an alloy and predicting cyclic life for isothermal and thermomechanical fatigue conditions by using the total strain version of strainrange partitioning (TS-SRP). Numerical examples are given. Two independent alloy characteristics are deemed important: failure behavior, as reflected by the inelastic strainrange versus cyclic life relations; and flow behavior, as indicated by the cyclic stress-strain-time response (i.e., the constitutive behavior). Failure behavior is characterized by conducting creep-fatigue tests in the strain regime, wherein the testing times are reasonably short and the inelastic strains are large enough to be determined accurately. At large strainranges, stress-hold, strain-limited tests are preferred because a high rate of creep damage per cycle is inherent in this type of test. At small strainranges, strain-hold cycles are more appropriate. Flow behavior is characterized by conducting tests wherein the specimen is usually cycled far short of failure and the wave shape is appropriate for the duty cycle of interest. In characterizing an alloy pure fatigue, or PP, failure tests are conducted first. Then depending on the needs of the analyst a series of creep-fatigue tests are conducted. As many of the three generic SRP cycles are featured as are required to characterize the influence of creep on fatigue life (i.e., CP, PC, and CC cycles, respectively, for tensile creep only, compressive creep only, and both tensile and compressive creep). Any mean stress effects on life also must be determined and accounted for when determining the SRP inelastic strainrange versus life relations for cycles featuring creep. This is particularly true for small strainranges. The life relations thus are established for a theoretical zero mean stress condition.

Point force singularities outside a drop covered with an incompressible surfactant: Image systems and their applications

NASA Astrophysics Data System (ADS)

Shaik, Vaseem A.; Ardekani, Arezoo M.

2017-11-01

In this work we derive the image flow fields for point force singularities placed outside a stationary drop covered with an insoluble, nondiffusing, and incompressible surfactant. We assume the interface to be Newtonian and use the Boussinesq-Scriven constitutive law for the interfacial stress tensor. We use this analytical solution to investigate two different problems. First, we derive the mobility matrix for two drops of arbitrary sizes covered with an incompressible surfactant. In the second example, we calculate the velocity of a swimming microorganism (modeled as a Stokes dipole) outside a drop covered with an incompressible surfactant.

Turbulence: The chief outstanding difficulty of our subject

NASA Technical Reports Server (NTRS)

Bradshaw, Peter

1992-01-01

A review of interesting current topics in turbulence research is decorated with examples of popular fallacies about the behavior of turbulence. Topics include the status of the Law of the Wall, especially in compressible flow; analogies between the effects of Reynolds numbers, pressure gradient, unsteadiness and roughness change; the status of Kolmogorov's universal equilibrium theory and local isotropy of the small eddies; turbulence modelling, with reference to universality, pressure-strain modelling and the dissipation equation; and chaos. Fallacies include the mixing-length concept; the effect of pressure gradient on Reynolds shear stress; the separability of time and space derivatives; models of the dissipation equation; and chaos.

CFD-DEM Onset of Motion Analysis for Application to Bed Scour Risk Assessment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sitek, M. A.; Lottes, S. A.

This CFD study with DEM was done as a part of the Federal Highway Administration’s (FHWA’s) effort to improve scour design procedures. The Computational Fluid Dynamics-Discrete Element Method (CFD-DEM) model, available in CD-Adapco’s StarCCM+ software, was used to simulate multiphase systems, mainly those which combine fluids and solids. In this method the motion of discrete solids is accounted for by DEM, which applies Newton's laws of motion to every particle. The flow of the fluid is determined by the local averaged Navier–Stokes equations that can be solved using the traditional CFD approach. The interactions between the fluid phase and solidsmore » phase are modeled by use of Newton's third law. The inter-particle contact forces are included in the equations of motion. Soft-particle formulation is used, which allows particles to overlap. In this study DEM was used to model separate sediment grains and spherical particles laying on the bed with the aim to analyze their movement due to flow conditions. Critical shear stress causing the incipient movement of the sediment was established and compared to the available experimental data. An example of scour around a cylindrical pier is considered. Various depths of the scoured bed and flow conditions were taken into account to gain a better understanding of the erosion forces existing around bridge foundations. The decay of these forces with increasing scour depth was quantified with a ‘decay function’, which shows that particles become increasingly less likely to be set in motion by flow forces as a scour hole increases in depth. Computational and experimental examples of the scoured bed around a cylindrical pier are presented.« less

A multi-component parallel-plate flow chamber system for studying the effect of exercise-induced wall shear stress on endothelial cells.

PubMed

Wang, Yan-Xia; Xiang, Cheng; Liu, Bo; Zhu, Yong; Luan, Yong; Liu, Shu-Tian; Qin, Kai-Rong

2016-12-28

In vivo studies have demonstrated that reasonable exercise training can improve endothelial function. To confirm the key role of wall shear stress induced by exercise on endothelial cells, and to understand how wall shear stress affects the structure and the function of endothelial cells, it is crucial to design and fabricate an in vitro multi-component parallel-plate flow chamber system which can closely replicate exercise-induced wall shear stress waveforms in artery. The in vivo wall shear stress waveforms from the common carotid artery of a healthy volunteer in resting and immediately after 30 min acute aerobic cycling exercise were first calculated by measuring the inner diameter and the center-line blood flow velocity with a color Doppler ultrasound. According to the above in vivo wall shear stress waveforms, we designed and fabricated a parallel-plate flow chamber system with appropriate components based on a lumped parameter hemodynamics model. To validate the feasibility of this system, human umbilical vein endothelial cells (HUVECs) line were cultured within the parallel-plate flow chamber under abovementioned two types of wall shear stress waveforms and the intracellular actin microfilaments and nitric oxide (NO) production level were evaluated using fluorescence microscope. Our results show that the trends of resting and exercise-induced wall shear stress waveforms, especially the maximal, minimal and mean wall shear stress as well as oscillatory shear index, generated by the parallel-plate flow chamber system are similar to those acquired from the common carotid artery. In addition, the cellular experiments demonstrate that the actin microfilaments and the production of NO within cells exposed to the two different wall shear stress waveforms exhibit different dynamic behaviors; there are larger numbers of actin microfilaments and higher level NO in cells exposed in exercise-induced wall shear stress condition than resting wall shear stress condition. The parallel-plate flow chamber system can well reproduce wall shear stress waveforms acquired from the common carotid artery in resting and immediately after exercise states. Furthermore, it can be used for studying the endothelial cells responses under resting and exercise-induced wall shear stress environments in vitro.

Modelling of a Francis Turbine Runner Fatigue Failure Process Caused by Fluid-Structure Interaction

NASA Astrophysics Data System (ADS)

Lyutov, A.; Kryukov, A.; Cherny, S.; Chirkov, D.; Salienko, A.; Skorospelov, V.; Turuk, P.

2016-11-01

In the present paper considered is the problem of the numerical simulation of Francis turbine runner fatigue failure caused by fluid-structure interaction. The unsteady 3D flow is modeled simultaneously in the spiral chamber, each wicket gate and runner channels and in the draft tube using the Euler equations. Based on the unsteady runner loadings at each time step stresses in the whole runner are calculated using the elastic equilibrium equations solved with boundary element method. Set of static stress-strain states provides quasi-dynamics of runner cyclic loading. It is assumed that equivalent stresses in the runner are below the critical value after which irreversible plastic processes happen in the runner material. Therefore runner is subjected to the fatigue damage caused by high-cycle fatigue, in which the loads are generally low compared with the limit stress of the material. As a consequence, the stress state around the crack front can be fully characterized by linear elastic fracture mechanics. The place of runner cracking is determined as a point with maximal amplitude of stress oscillations. Stress pulsations amplitude is used to estimate the number of cycles until the moment of fatigue failure, number of loading cycles and oscillation frequency are used to calculate runner service time. Example of the real Francis runner which has encountered premature fatigue failure as a result of incorrect durability estimation is used to verify the developed numerical model.

Oxygen and carbon dioxide transport in time-dependent blood flow past fiber rectangular arrays

NASA Astrophysics Data System (ADS)

Zierenberg, Jennifer R.; Fujioka, Hideki; Hirschl, Ronald B.; Bartlett, Robert H.; Grotberg, James B.

2009-03-01

The influence of time-dependent flows on oxygen and carbon dioxide transport for blood flow past fiber arrays arranged in in-line and staggered configurations was computationally investigated as a model for an artificial lung. Both a pulsatile flow, which mimics the flow leaving the right heart and passing through a compliance chamber before entering the artificial lung, and a right ventricular flow, which mimics flow leaving the right heart and directly entering the artificial lung, were considered in addition to a steady flow. The pulsatile flow was modeled as a sinusoidal perturbation superimposed on a steady flow while the right ventricular flow was modeled to accurately depict the period of flow acceleration (increasing flow) and deceleration (decreasing flow) during systole followed by zero flow during diastole. It was observed that the pulsatile flow yielded similar gas transport as compared to the steady flow, while the right ventricular flow resulted in smaller gas transport, with the decrease increasing with Re. The pressure drop across the fiber array (a measure of the resistance), work (an indicator of the work required of the right heart), and shear stress (a measure of potential blood cell activation and damage) are lowest for steady flow, followed by pulsatile flow, and then right ventricular flow. The pressure drop, work, shear stress, and Sherwood numbers (a measure of the gas transport efficiency) decrease with increasing porosity and are smaller for AR <1 as compared to AR >1 (AR is the distance between fibers in the flow direction/distance between fibers in direction perpendicular to flow), although for small porosities the Sherwood numbers are of similar magnitude. In general, for any fiber array geometry, high pressure drop, work, and shear stresses correlate with high Sherwood numbers, and low pressure drop, work, and shear stresses correlate with low Sherwood numbers creating a need for a compromise between pressure drop/work/shear stresses and gas transport.

Ionization based multi-directional flow sensor

DOEpatents

Chorpening, Benjamin T [Morgantown, WV; Casleton, Kent H [Morgantown, WV

2009-04-28

A method, system, and apparatus for conducting real-time monitoring of flow (airflow for example) in a system (a hybrid power generation system for example) is disclosed. The method, system and apparatus measure at least flow direction and velocity with minimal pressure drop and fast response. The apparatus comprises an ion source and a multi-directional collection device proximate the ion source. The ion source is configured to generate charged species (electrons and ions for example). The multi-directional collection source is configured to determine the direction and velocity of the flow in real-time.

Multi-dimensional rheology-based two-phase model for sediment transport and applications to sheet flow and pipeline scour

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lee, Cheng-Hsien; Department of Water Resources and Environmental Engineering, Tamkang University, New Taipei City 25137, Taiwan; Low, Ying Min, E-mail: ceelowym@nus.edu.sg

2016-05-15

Sediment transport is fundamentally a two-phase phenomenon involving fluid and sediments; however, many existing numerical models are one-phase approaches, which are unable to capture the complex fluid-particle and inter-particle interactions. In the last decade, two-phase models have gained traction; however, there are still many limitations in these models. For example, several existing two-phase models are confined to one-dimensional problems; in addition, the existing two-dimensional models simulate only the region outside the sand bed. This paper develops a new three-dimensional two-phase model for simulating sediment transport in the sheet flow condition, incorporating recently published rheological characteristics of sediments. The enduring-contact, inertial,more » and fluid viscosity effects are considered in determining sediment pressure and stresses, enabling the model to be applicable to a wide range of particle Reynolds number. A k − ε turbulence model is adopted to compute the Reynolds stresses. In addition, a novel numerical scheme is proposed, thus avoiding numerical instability caused by high sediment concentration and allowing the sediment dynamics to be computed both within and outside the sand bed. The present model is applied to two classical problems, namely, sheet flow and scour under a pipeline with favorable results. For sheet flow, the computed velocity is consistent with measured data reported in the literature. For pipeline scour, the computed scour rate beneath the pipeline agrees with previous experimental observations. However, the present model is unable to capture vortex shedding; consequently, the sediment deposition behind the pipeline is overestimated. Sensitivity analyses reveal that model parameters associated with turbulence have strong influence on the computed results.« less

Numerical and In Vitro Experimental Investigation of the Hemolytic Performance at the Off-Design Point of an Axial Ventricular Assist Pump.

PubMed

Liu, Guang-Mao; Jin, Dong-Hai; Jiang, Xi-Hang; Zhou, Jian-Ye; Zhang, Yan; Chen, Hai-Bo; Hu, Sheng-Shou; Gui, Xing-Min

The ventricular assist pumps do not always function at the design point; instead, these pumps may operate at unfavorable off-design points. For example, the axial ventricular assist pump FW-2, in which the design point is 5 L/min flow rate against 100 mm Hg pressure increase at 8,000 rpm, sometimes works at off-design flow rates of 1 to 4 L/min. The hemolytic performance of the FW-2 at both the design point and at off-design points was estimated numerically and tested in vitro. Flow characteristics in the pump were numerically simulated and analyzed with special attention paid to the scalar sheer stress and exposure time. An in vitro hemolysis test was conducted to verify the numerical results. The simulation results showed that the scalar shear stress in the rotor region at the 1 L/min off-design point was 70% greater than at the 5 L/min design point. The hemolysis index at the 1 L/min off-design point was 3.6 times greater than at the 5 L/min design point. The in vitro results showed that the normalized index of hemolysis increased from 0.017 g/100 L at the 5 L/min design point to 0.162 g/100 L at the 1 L/min off-design point. The hemolysis comparison between the different blood pump flow rates will be helpful for future pump design point selection and will guide the usage of ventricular assist pumps. The hemolytic performance of the blood pump at the working point in the clinic should receive more focus.

Porosity modification during and following deposition of deep-water sediments

NASA Astrophysics Data System (ADS)

Butler, R. W.; McCaffrey, W. D.; Haughton, P.; del Pino Sanchez, A.; Barker, S.; Hailwood, E.; Hakes, B.

2005-12-01

Deposition and early burial of sediments, especially sandy turbidites, are commonly accompanied by the reorganization of porosity structure through the localized expulsion of interstitial fluid. Fluid escape structures are preserved as thin sheets and pipes. Coeval sediment remobilization may be represented by shear structures, commonly taken to indicate down-slope creep and slumping. The history of shearing vs dewatering may be established from cross-cutting structures preserved in outcrop and/or core. Although these relationships are known for gravity-driven soft-sediment deformation on submarine slopes, they can also develop during deposition itself due to shear from the over-riding flow. Such deformation features, including pseudo s-c fabrics and distributed shear, together may previously have been misinterpreted as indicators of palaeoslope (slumps) or even of tectonic deformation. Progressive aggradation of sandy turbidites can show complex banded facies within which soft-sediment deformation is tiered. Syn-deposition micro-growth strata testify to ongoing seabed deformation occurring beneath active flows, while the bedforms themselves provide direct measurements of the magnitude of shear stresses imparted into the seabed and estimates of the shear strength of this substrate. Such banded facies may be interpreted in terms of cyclic partitioning of shear stress into the flow and the substrate. The modified porosity structures and related heterogeneities in permeability of such materials may persist during deeper burial, influencing the rheology of the sediment. These bed-scale processes are reflected in the quality and flow rates of hydrocarbon reservoirs. The reorganization of sand-body architecture through remobilization, by traction and/or down-slope failure, also has a strong impact on the permeability on the multi-bed scale (10s-100s m). Examples will be presented from hydrocarbon reservoirs in the subsurface and from outcrops of Tertiary turbidites in the Alpine-Apennine orogenic system.

Yield stress materials in soft condensed matter

NASA Astrophysics Data System (ADS)

Bonn, Daniel; Denn, Morton M.; Berthier, Ludovic; Divoux, Thibaut; Manneville, Sébastien

2017-07-01

A comprehensive review is presented of the physical behavior of yield stress materials in soft condensed matter, which encompasses a broad range of materials from colloidal assemblies and gels to emulsions and non-Brownian suspensions. All these disordered materials display a nonlinear flow behavior in response to external mechanical forces due to the existence of a finite force threshold for flow to occur: the yield stress. Both the physical origin and rheological consequences associated with this nonlinear behavior are discussed and an overview is given of experimental techniques available to measure the yield stress. Recent progress is discussed concerning a microscopic theoretical description of the flow dynamics of yield stress materials, emphasizing, in particular, the role played by relaxation time scales, the interplay between shear flow and aging behavior, the existence of inhomogeneous shear flows and shear bands, wall slip, and nonlocal effects in confined geometries.

Two-axis direct fluid shear stress sensor

NASA Technical Reports Server (NTRS)

Bajikar, Sateesh (Inventor); Scott, Michael A. (Inventor); Adcock, Edward E. (Inventor)

2011-01-01

A micro sized multi-axis semiconductor skin friction/wall shear stress induced by fluid flow. The sensor design includes a shear/strain transduction gimble connected to a force collecting plate located at the flow boundary surface. The shear force collecting plate is interconnected by an arm to offset the tortional hinges from the fluid flow. The arm is connected to the shear force collecting plate through dual axis torsional hinges with piezoresistive torsional strain gauges. These gauges are disposed on the tortional hinges and provide a voltage output indicative of applied shear stress acting on the force collection plate proximate the flow boundary surface. Offsetting the torsional hinges creates a force concentration and resolution structure that enables the generation of a large stress on the strain gauge from small shear stress, or small displacement of the collecting plate. The design also isolates the torsional sensors from exposure to the fluid flow.

ESTIMATION OF SHEAR STRESS WORKING ON SUBMERGED HOLLOW FIBRE MEMBRANE BY CFD METHOD IN MBRs

NASA Astrophysics Data System (ADS)

Zaw, Hlwan Moe; Li, Tairi; Nagaoka, Hiroshi

This study was conducted to evaluate shear stress working on submerged hollow fibre membrane by CFD (Computation Fluid Dynamics) method in MBRs. Shear stress on hollow fibre membrane caused by aeration was measured directly using a two-direction load sensor. The measurement of water-phase flow velocity was done also by using laser doppler velocimeter. It was confirmed that the shear stress was possible to be evaluated from the water-phase flow velocityby the result of comparison of time average shear stress actually measured with one hollow fibre membrane and the one calculated by the water-phase flow velocity. In the estimation of the water-phase flow velocity using the CFD method, time average water-phase flow velocity estimated by consideration of the fluid resistance of the membrane module nearly coincided with the measured values, and it was shown that it was possible to be estimated also within the membrane module. Moreover, the measured shear stress and drag force well coincided with the values calculated from the estimated water-phase flow velocity outside of membrane module and in the center of membrane module, and it was suggested that the shear stress on the hollow fibre membrane could be estimated by the CFD method in MBRs.

Effects of Temperature and Strain Rate on Tensile Deformation Behavior of 9Cr-0.5Mo-1.8W-VNb Ferritic Heat-Resistant Steel

NASA Astrophysics Data System (ADS)

Guo, Xiaofeng; Weng, Xiaoxiang; Jiang, Yong; Gong, Jianming

2017-09-01

A series of uniaxial tensile tests were carried out at different strain rate and different temperatures to investigate the effects of temperature and strain rate on tensile deformation behavior of P92 steel. In the temperature range of 30-700 °C, the variations of flow stress, average work-hardening rate, tensile strength and ductility with temperature all show three temperature regimes. At intermediate temperature, the material exhibited the serrated flow behavior, the peak in flow stress, the maximum in average work-hardening rate, and the abnormal variations in tensile strength and ductility indicates the occurrence of DSA, whereas the sharp decrease in flow stress, average work-hardening rate as well as strength values, and the remarkable increase in ductility values with increasing temperature from 450 to 700 °C imply that dynamic recovery plays a dominant role in this regime. Additionally, for the temperature ranging from 550 to 650 °C, a significant decrease in flow stress values is observed with decreasing in strain rate. This phenomenon suggests the strain rate has a strong influence on flow stress. Based on the experimental results above, an Arrhenius-type constitutive equation is proposed to predict the flow stress.

Stationary holographic plasma quenches and numerical methods for non-killing horizons.

PubMed

Figueras, Pau; Wiseman, Toby

2013-04-26

We explore use of the harmonic Einstein equations to numerically find stationary black holes where the problem is posed on an ingoing slice that extends into the interior of the black hole. Requiring no boundary conditions at the horizon beyond smoothness of the metric, this method may be applied for horizons that are not Killing. As a nontrivial illustration we find black holes which, via AdS-CFT, describe a time-independent CFT plasma flowing through a static spacetime which asymptotes to Minkowski in the flow's past and future, with a varying spatial geometry in between. These are the first nonperturbative examples of stationary black holes which do not have Killing horizons. When the CFT spacetime slowly varies, the CFT stress tensor derived from gravity is well described by viscous hydrodynamics. For fast variation it is not, and the solutions are stationary analogs of dynamical quenches, with the plasma being suddenly driven out of equilibrium. We find evidence these flows become unstable for sufficiently strong quenches, and speculate the instability may be turbulent.

Interactive Effects of Nutrient and Mechanical Stresses on Plant Morphology

PubMed Central

Puijalon, Sara; Lena, Jean-Paul; Bornette, Gudrun

2007-01-01

Background and Aims Plant species frequently encounter multiple stresses under natural conditions, and the way they cope with these stresses is a major determinant of their ecological breadth. The way mechanical (e.g. wind, current) and resource stresses act simultaneously on plant morphological traits has been poorly addressed, even if both stresses often interact. This paper aims to assess whether hydraulic stress affects plant morphology in the same way at different nutrient levels. Methods An examination was made of morphological variations of an aquatic plant species growing under four hydraulic stress (flow velocity) gradients located in four habitats distributed along a nutrient gradient. Morphological traits covering plant size, dry mass allocation, organ water content and foliage architecture were measured. Key Results Significant interactive effects of flow velocity and nutrient level were observed for all morphological traits. In particular, increased flow velocity resulted in size reductions under low nutrient conditions, suggesting an adaptive response to flow stress (escape strategy). On the other hand, moderate increases in flow velocity resulted in increased size under high nutrient conditions, possibly related to an inevitable growth response to a higher nutrient supply induced by water renewal at the plant surface. For some traits (e.g. dry mass allocation), a consistent sense of variation as a result of increasing flow velocity was observed, but the amount of variation was either reduced or amplified under nutrient-rich compared with nutrient-poor conditions, depending on the traits considered. Conclusions These results suggest that, for a given species, a stress factor may result, in contrasting patterns and hence strategies, depending on a second stress factor. Such results emphasize the relevance of studies on plant responses to multiple stresses for understanding the actual ecological breadth of species. PMID:17913725

An in vitro investigation of the influence of stenosis severity on the flow in the ascending aorta.

PubMed

Gülan, Utku; Lüthi, Beat; Holzner, Markus; Liberzon, Alex; Tsinober, Arkady; Kinzelbach, Wolfgang

2014-09-01

Cardiovascular diseases can lead to abnormal blood flows, some of which are linked to hemolysis and thrombus formation. Abnormal turbulent flows of blood in the vessels with stenosis create strong shear stresses on blood elements and may cause blood cell destruction or platelet activation. We implemented a Lagrangian (following the fluid elements) measurement technique of three dimensional particle tracking velocimetry that provides insight on the evolution of viscous and turbulent stresses along blood element trajectories. We apply this method to study a pulsatile flow in a compliant phantom of an aorta and compare the results in three cases: the reference case (called "healthy" case), and two cases of abnormal flows due to mild and severe stenosis, respectively. The chosen conditions can mimic a clinical application of an abnormal flow due to a calcific valve. We estimate the effect of aortic stenosis on the kinetic energy of the mean flow and the turbulent kinetic energy, which increases about two orders of magnitude as compared with the healthy flow case. Measuring the total flow stress acting on a moving fluid element that incorporates viscous stresses and the apparent turbulent-induced stresses (the so-called Reynolds stresses) we find out similar increase of the stresses with the increased severity of the stenosis. Furthermore, these unique Lagrangian measurements provide full acceleration and, consequently, the forces acting on the blood elements that are estimated to reach the level that can considerably deform red blood cells. These forces are strong and abrupt due to the contribution of the turbulent fluctuations which is much stronger than the typically measured phase-averaged values. Copyright © 2014 IPEM. Published by Elsevier Ltd. All rights reserved.

A Near-Wall Reynolds-Stress Closure without Wall Normals

NASA Technical Reports Server (NTRS)

Yuan, S. P.; So, R. M. C.

1997-01-01

With the aid of near-wall asymptotic analysis and results of direct numerical simulation, a new near-wall Reynolds stress model (NNWRS) is formulated based on the SSG high-Reynolds-stress model with wall-independent near-wall corrections. Only one damping function is used for flows with a wide range of Reynolds numbers to ensure that the near-wall modifications diminish away from the walls. The model is able to reproduce complicated flow phenomena induced by complex geometry, such as flow recirculation, reattachment and boundary-layer redevelopment in backward-facing step flow and secondary flow in three-dimensional square duct flow. In simple flows, including fully developed channel/pipe flow, Couette flow and boundary-layer flow, the wall effects are dominant, and the NNWRS model predicts less degree of turbulent anisotropy in the near-wall region compared with a wall-dependent near-wall Reynolds Stress model (NWRS) developed by So and colleagues. The comparison of the predictions given by the two models rectifies the misconception that the overshooting of skin friction coefficient in backward-facing step flow prevalent in those near-wall, models with wall normal is caused by he use of wall normal.

A Near-Wall Reynolds-Stress Closure Without Wall Normals

NASA Technical Reports Server (NTRS)

Yuan, S. P.; So, R. M. C.

1997-01-01

Turbulent wall-bounded complex flows are commonly encountered in engineering practice and are of considerable interest in a variety of industrial applications. The presence of a wall significantly affects turbulence characteristics. In addition to the wall effects, turbulent wall-bounded flows become more complicated by the presence of additional body forces (e.g. centrifugal force and Coriolis force) and complex geometry. Most near-wall Reynolds stress models are developed from a high-Reynolds-number model which assumes turbulence is homogenous (or quasi-homogenous). Near-wall modifications are proposed to include wall effects in near-wall regions. In this process, wall normals are introduced. Good predictions could be obtained by Reynolds stress models with wall normals. However, ambiguity arises when the models are applied in flows with multiple walls. Many models have been proposed to model turbulent flows. Among them, Reynolds stress models, in which turbulent stresses are obtained by solving the Reynolds stress transport equations, have been proved to be the most successful ones. To apply the Reynolds stress models to wall-bounded flows, near-wall corrections accounting for the wall effects are needed, and the resulting models are called near-wall Reynolds stress models. In most of the existing near-wall models, the near-wall corrections invoke wall normals. These wall-dependent near-wall models are difficult to implement for turbulent flows with complex geometry and may give inaccurate predictions due to the ambiguity of wall normals at corners connecting multiple walls. The objective of this study is to develop a more general and flexible near-wall Reynolds stress model without using any wall-dependent variable for wall-bounded turbulent flows. With the aid of near-wall asymptotic analysis and results of direct numerical simulation, a new near-wall Reynolds stress model (NNWRS) is formulated based on Speziale et al.'s high-Reynolds-stress model with wall-independent near-wall corrections. Moreover, only one damping function is used for flows with a wide range of Reynolds numbers to ensure that the near-wall modifications diminish away from the walls.

Synopsis of Past Stimulation Methods in Enhanced (Engineered) Geothermal Systems, Boreholes, and Existing Hydrothermal Systems with Success Analysis and Recommendations for Future Projects

NASA Astrophysics Data System (ADS)

Broadhurst, T.; Mattson, E.

2017-12-01

Enhanced geothermal systems (EGS) are gaining in popularity as a technology that can be used to increase areas for geothermal resource procurement. One of the most important factors in the success of an EGS system is the success of the subsurface reservoir that is used for fluid flow and heat mining through advection. There are numerous challenges in stimulating a successful reservoir, including maintaining flow rates, minimizing leak off, preventing short-circuiting, and reducing the risk of microseismicity associated with subsurface activity. Understanding past examples of stimulation can be invaluable in addressing these challenges. This study provides an overview of stimulation methods that have been employed in EGS systems from 1974-2017. We include all geothermal reservoirs and demonstration projects that have experienced hydrofracturing, chemical stimulation, and induced thermal stress for a comprehensive list. We also examine different metrics and measures of success in geothermal reservoir stimulation to draw conclusions and provide recommendations for future projects. Multiple project characteristics are reported including geologic setting, stress conditions, reservoir temperature, injection specifics, resulting microseismicity, and overall project goals. Insight into optimal and unproductive stimulation methods is crucial to conserving mental capital, utilizing project funding, and ensuring EGS technology advances as efficiently as possible.

Evaluation of Aortic Blood Flow and Wall Shear Stress in Aortic Stenosis and Its Association With Left Ventricular Remodeling.

PubMed

von Knobelsdorff-Brenkenhoff, Florian; Karunaharamoorthy, Achudhan; Trauzeddel, Ralf Felix; Barker, Alex J; Blaszczyk, Edyta; Markl, Michael; Schulz-Menger, Jeanette

2016-03-01

Aortic stenosis (AS) leads to variable stress for the left ventricle (LV) and consequently a broad range of LV remodeling. The aim of this study was to describe blood flow patterns in the ascending aorta of patients with AS and determine their association with remodeling. Thirty-seven patients with AS (14 mild, 8 moderate, 15 severe; age, 63±13 years) and 37 healthy controls (age, 60±10 years) underwent 4-dimensional-flow magnetic resonance imaging. Helical and vortical flow formations and flow eccentricity were assessed in the ascending aorta. Normalized flow displacement from the vessel center and peak systolic wall shear stress in the ascending aorta were quantified. LV remodeling was assessed based on LV mass index and the ratio of LV mass:end-diastolic volume (relative wall mass). Marked helical and vortical flow formation and eccentricity were more prevalent in patients with AS than in healthy subjects, and patients with AS exhibited an asymmetrical and elevated distribution of peak systolic wall shear stress. In AS, aortic orifice area was strongly negatively associated with vortical flow formation (P=0.0274), eccentricity (P=0.0070), and flow displacement (P=0.0021). Bicuspid aortic valve was associated with more intense helical (P=0.0098) and vortical flow formation (P=0.0536), higher flow displacement (P=0.11), and higher peak systolic wall shear stress (P=0.0926). LV mass index and relative wall mass were significantly associated with aortic orifice area (P=0.0611, P=0.0058) and flow displacement (P=0.0058, P=0.0283). In this pilot study, AS leads to abnormal blood flow pattern and peak systolic wall shear stress in the ascending aorta. In addition to aortic orifice area, normalized flow displacement was significantly associated with LV remodeling. © 2016 American Heart Association, Inc.

A Galilean Invariant Explicit Algebraic Reynolds Stress Model for Curved Flows

NASA Technical Reports Server (NTRS)

Girimaji, Sharath

1996-01-01

A Galilean invariant weak-equilbrium hypothesis that is sensitive to streamline curvature is proposed. The hypothesis leads to an algebraic Reynolds stress model for curved flows that is fully explicit and self-consistent. The model is tested in curved homogeneous shear flow: the agreement is excellent with Reynolds stress closure model and adequate with available experimental data.

Characterization Of Flow Stress Of Different AA6082 Alloys By Means Of Hot Torsion Test

NASA Astrophysics Data System (ADS)

Donati, Lorenzo; El Mehtedi, Mohamad

2011-05-01

FEM simulations are become the most powerful tools in order to optimize the different aspects of the extrusion process and an accurate flow stress definition of the alloy is a prerequisite for a reliable effectiveness of the simulation. In the paper the determination of flow stress by means of hot torsion test is initially presented and discussed: the several approximations that are usually introduced in flow stress computation are described and computed for an AA6082 alloy in order to evidence the final effect on curves shapes. The procedure for regressing the parameters of the sinhyperbolic flow stress definition is described in detailed and applied to the described results. Then four different alloys, extracted by different casting batches but all namely belonging to the 6082 class, were hot torsion tested in comparable levels of temperature and strain rate up to specimen failure. The results are analyzed and discussed in order to understand if a mean flow stress behavior can be identified for the whole material class at the different tested conditions or if specific testing conditions (chemical composition of the alloy, specimen shape, etc) influence the materials properties to a higher degree.

Characterization of geomorphic units in the alluvial valleys and channels of Gulf Coastal Plain rivers in Texas, with examples from the Brazos, Sabine, and Trinity Rivers, 2010

USGS Publications Warehouse

Coffman, David K.; Malstaff, Greg; Heitmuller, Franklin T.

2011-01-01

The U.S. Geological Survey, in cooperation with the Texas Water Development Board, described and characterized examples of geomorphic units within the channels and alluvial valleys of Texas Gulf Coastal Plain rivers using a geomorphic unit classification scale that differentiates geomorphic units on the basis of their location either outside or inside the river channel. The geomorphic properties of a river system determine the distribution and type of potential habitat both within and adjacent to the channel. This report characterizes the geomorphic units contained in the river channels and alluvial valleys of Texas Gulf Coastal Plain rivers in the context of the River Styles framework. This report is intended to help Texas Instream Flow Program practitioners, river managers, ecologists and biologists, and others interested in the geomorphology and the physical processes of the rivers of the Texas Gulf Coastal Plain (1) gain insights into how geomorphic units develop and adjust spatially and temporally, and (2) be able to recognize common geomorphic units from the examples cataloged in this report. Recent aerial imagery (high-resolution digital orthoimagery) collected in 2008 and 2009 were inspected by using geographic information system software to identify representative examples of the types of geomorphic units that occurred in the study area. Geomorphic units outside the channels of Texas Gulf Coastal Plain rivers are called \\"valley geomorphic units\\" in this report. Valley geomorphic units for the Texas Gulf Coastal Plain rivers described in this report are terraces, flood plains, crevasses and crevasse splays, flood-plain depressions, tie channels, tributaries, paleochannels, anabranches, distributaries, natural levees, neck cutoffs, oxbow lakes, and constructed channels. Channel geomorphic units occur in the river channel and are subject to frequent stresses associated with flowing water and sediment transport; they adjust (change) relatively quickly in response to short-term variations in flow. Channel geomorphic units described in this report are channel banks, benches and ledges, bank failures, point bars, cross-bar channels, channel bars, exposed bedrock, pools, runs, and crossovers.

A New Reynolds Stress Algebraic Equation Model

NASA Technical Reports Server (NTRS)

Shih, Tsan-Hsing; Zhu, Jiang; Lumley, John L.

1994-01-01

A general turbulent constitutive relation is directly applied to propose a new Reynolds stress algebraic equation model. In the development of this model, the constraints based on rapid distortion theory and realizability (i.e. the positivity of the normal Reynolds stresses and the Schwarz' inequality between turbulent velocity correlations) are imposed. Model coefficients are calibrated using well-studied basic flows such as homogeneous shear flow and the surface flow in the inertial sublayer. The performance of this model is then tested in complex turbulent flows including the separated flow over a backward-facing step and the flow in a confined jet. The calculation results are encouraging and point to the success of the present model in modeling turbulent flows with complex geometries.

A crystallographic model for the tensile and fatigue response for Rene N4 at 982 C

NASA Technical Reports Server (NTRS)

Sheh, M. Y.; Stouffer, D. C.

1990-01-01

An anisotropic constitutive model based on crystallographic slip theory was formulated for nickel-base single-crystal superalloys. The current equations include both drag stress and back stress state variables to model the local inelastic flow. Specially designed experiments have been conducted to evaluate the existence of back stress in single crystals. The results showed that the back stress effect of reverse inelastic flow on the unloading stress is orientation-dependent, and a back stress state variable in the inelastic flow equation is necessary for predicting inelastic behavior. Model correlations and predictions of experimental data are presented for the single crystal superalloy Rene N4 at 982 C.

Inertial flow regimes of the suspension of finite size particles

NASA Astrophysics Data System (ADS)

Lashgari, Iman; Picano, Francesco; Brandt, Luca

2015-03-01

We study inertial flow regimes of the suspensions of finite size neutrally buoyant particles. These suspensions experience three different regimes by varying the Reynolds number, Re , and particle volume fraction, Φ. At low values of Re and Φ, flow is laminar-like where viscous stress is the dominating term in the stress budget. At high Re and relatively small Φ, the flow is turbulent-like where Reynolds stress has the largest contribution to the total stress. At high Φ, the flow regime is as a form of inertial shear-thickening characterized by a significant enhancement in the wall shear stress not due to the increment of Reynolds stress but to the particle stress. We further analyze the local behavior of the suspension in the three different regimes by studying the particle dispersion and collisions. Turbulent cases shows higher level of particle dispersion and higher values of the collision kernel (the radial distribution function times the particle relative velocity as a function of the distance between the particles) than those of the inertial shear-thickening regimes providing additional evidence of two different transport mechanisms in the Bagnoldian regime. Support from the European Research Council (ERC) is acknowledged.

Spatial heterogeneity of stress and driving fluid pressure ratio inferred from mineral vein orientation along seismogenic megasplay fault (Nobeoka Thrust, Japan)

NASA Astrophysics Data System (ADS)

Otsubo, M.; Miyakawa, A.; Kawasaki, R.; Sato, K.; Yamaguchi, A.; Kimura, G.

2015-12-01

Fault zones including the damage zone and the fault core have a controlling influence on the crust's mechanical and fluid flow properties (e.g., Faulkner et al., 2010). In the Nankai subduction zone, southwest Japan, the velocity structures indicate the contrast of the pore fluid pressure between hanging wall and footwall of the megasplay fault (Tsuji et al., 2014). Nobeoka Thrust, which is an on-land example of an ancient megasplay fault, provides an excellent record of deformation and fluid flow at seismogenic depths (Kondo et al., 2005; Yamaguchi et al., 2011). Yamaguchi et al. (2011) showed that the microchemical features of syn-tectonic mineral veins along fault zones of the Nobeoka Thrust. The inversion approaches by using the mineral vein orientations can provide stress regimes and fluid driving pressure ratio (Jolly and Sanderson, 1997) at the time of fracture opening (e.g., Yamaji et al., 2010). In this study, we show (1) stress regimes in co- and post seismic period of the Nobeoka Thrust and (2) spatial heterogeneity of the fluid driving pressure ratio by using the mineral veins (extension veins) around the fault zone in the Nobeoka Thrust. We applied the inversion approach proposed by Sato et al. (2013) to estimate stress regimes by using the mineral vein orientations. The estimated stresses are the normal faulting stress regimes of which sigma 3 axes are almost horizontal and trend NNW-SSE in both the hanging wall and the footwall. The stress regimes are the negative stress for the reverse faulting stress regime that Kawasaki et al. (2014) estimated from the minor faults in the core samples of the Nobeoka Thrust Drilling Project (Hamahashi et al., 2013). And, the orientation of the sigma 3 axes of the estimated stress regime is parallel to the slip direction of the Nobeoka Thrust (Top to SSE; Kondo et al., 2005). These facts indicate the normal faulting stress regime at the time of fracture opening is the secondary stress generated by the slip of the Nobeoka Thrust. We estimated the fluid driving pressure ratio P* at the time of fracture opening by using the Mohr circle analysis that has been carried out using the vein orientation data. The estimated P* are 0.05 and 0.15-0.40 in the hanging wall and footwall, respectively. These results indicate that there are spatial differences of pore fluid pressure in the interseismic period.

Turbulence significantly increases pressure and fluid shear stress in an aortic aneurysm model under resting and exercise flow conditions.

PubMed

Khanafer, Khalil M; Bull, Joseph L; Upchurch, Gilbert R; Berguer, Ramon

2007-01-01

The numerical models of abdominal aortic aneurysm (AAA) in use do not take into account the non-Newtonian behavior of blood and the development of local turbulence. This study examines the influence of pulsatile, turbulent, non-Newtonian flow on fluid shear stresses and pressure changes under rest and exercise conditions. We numerically analyzed pulsatile turbulent flow, using simulated physiological rest and exercise waveforms, in axisymmetric-rigid aortic aneurysm models (AAMs). Discretization of governing equations was achieved using a finite element scheme. Maximum turbulence-induced shear stress was found at the distal end of an AAM. In large AAMs (dilated to undilated diameter ratio = 3.33) at peak systolic flow velocity, fluid shear stress during exercise is 70.4% higher than at rest. Our study provides a numerical, noninvasive method for obtaining detailed data on the forces generated by pulsatile turbulent flow in AAAs that are difficult to study in humans and in physical models. Our data suggest that increased flow turbulence results in increased shear stress in aneurysms. While pressure readings are fairly uniform along the length of an aneurysm, the kinetic energy generated by turbulence impacting on the wall of the distal half of the aneurysm increases fluid and wall shear stress at this site. If the increased fluid shear stress results in further dilation and hence further turbulence, wall stress may be a mechanism for aneurysmal growth and eventual rupture.

Reducing RANS Model Error Using Random Forest

NASA Astrophysics Data System (ADS)

Wang, Jian-Xun; Wu, Jin-Long; Xiao, Heng; Ling, Julia

2016-11-01

Reynolds-Averaged Navier-Stokes (RANS) models are still the work-horse tools in the turbulence modeling of industrial flows. However, the model discrepancy due to the inadequacy of modeled Reynolds stresses largely diminishes the reliability of simulation results. In this work we use a physics-informed machine learning approach to improve the RANS modeled Reynolds stresses and propagate them to obtain the mean velocity field. Specifically, the functional forms of Reynolds stress discrepancies with respect to mean flow features are trained based on an offline database of flows with similar characteristics. The random forest model is used to predict Reynolds stress discrepancies in new flows. Then the improved Reynolds stresses are propagated to the velocity field via RANS equations. The effects of expanding the feature space through the use of a complete basis of Galilean tensor invariants are also studied. The flow in a square duct, which is challenging for standard RANS models, is investigated to demonstrate the merit of the proposed approach. The results show that both the Reynolds stresses and the propagated velocity field are improved over the baseline RANS predictions. SAND Number: SAND2016-7437 A

Correlation between vortices and wall shear stress in a curved artery model under pulsatile flow conditions

NASA Astrophysics Data System (ADS)

Cox, Christopher; Plesniak, Michael W.

2017-11-01

One of the most physiologically relevant factors within the cardiovascular system is the wall shear stress. The wall shear stress affects endothelial cells via mechanotransduction and atherosclerotic regions are strongly correlated with curvature and branching in the human vasculature, where the shear stress is both oscillatory and multidirectional. Also, the combined effect of curvature and pulsatility in cardiovascular flows produces unsteady vortices. In this work, our goal is to assess the correlation between multiple vortex pairs and wall shear stress. To accomplish this, we use an in-house high-order flux reconstruction Navier-Stokes solver to simulate pulsatile flow of a Newtonian blood-analog fluid through a rigid 180° curved artery model. We use a physiologically relevant flow rate and generate results using both fully developed and uniform entrance conditions, the latter motivated by the fact that flow upstream to a curved artery may not be fully developed. Under these two inflow conditions, we characterize the evolution of various vortex pairs and their subsequent effect on several wall shear stress metrics. Supported by GW Center for Biomimetics and Bioinspired Engineering.

An analysis of the characteristics of rough bed turbulent shear stresses in an open channel

NASA Astrophysics Data System (ADS)

Keshavarzy, A.; Ball, J. E.

1997-06-01

Entrainment of sediment particles from channel beds into the channel flow is influenced by the characteristics of the flow turbulence which produces stochastic shear stress fluctuations at the bed. Recent studies of the structure of turbulent flow has recognized the importance of bursting processes as important mechanisms for the transfer of momentum into the laminar boundary layer. Of these processes, the sweep event has been recognized as the most important bursting event for entrainment of sediment particles as it imposes forces in the direction of the flow resulting in movement of particles by rolling, sliding and occasionally saltating. Similarly, the ejection event has been recognized as important for sediment transport since these events maintain the sediment particles in suspension. In this study, the characteristics of bursting processes and, in particular, the sweep event were investigated in a flume with a rough bed. The instantaneous velocity fluctuations of the flow were measured in two-dimensions using a small electromagnetic velocity meter and the turbulent shear stresses were determined from these velocity fluctuations. It was found that the shear stress applied to the sediment particles on the bed resulting from sweep events depends on the magnitude of the turbulent shear stress and its probability distribution. A statistical analysis of the experimental data was undertaken and it was found necessary to apply a Box-Cox transformation to transform the data into a normally distributed sample. This enabled determination of the mean shear stress, angle of action and standard error of estimate for sweep and ejection events. These instantaneous shear stresses were found to be greater than the mean flow shear stress and for the sweep event to be approximately 40 percent greater near the channel bed. Results from this analysis suggest that the critical shear stress determined from Shield's diagram is not sufficient to predict the initiation of motion due to its use of the temporal mean shear stress. It is suggested that initiation of particle motion, but not continuous motion, can occur earlier than suggested by Shield's diagram due to the higher shear stresses imposed on the particles by the stochastic shear stresses resulting from turbulence within the flow.

Anomalous Transport in Natural Fracture Networks Induced by Tectonic Stress

NASA Astrophysics Data System (ADS)

Kang, P. K.; Lei, Q.; Lee, S.; Dentz, M.; Juanes, R.

2017-12-01

Fluid flow and transport in fractured rock controls many natural and engineered processes in the subsurface. However, characterizing flow and transport through fractured media is challenging due to the high uncertainty and large heterogeneity associated with fractured rock properties. In addition to these "static" challenges, geologic fractures are always under significant overburden stress, and changes in the stress state can lead to changes in the fracture's ability to conduct fluids. While confining stress has been shown to impact fluid flow through fractures in a fundamental way, the impact of confining stress on transportthrough fractured rock remains poorly understood. The link between anomalous (non-Fickian) transport and confining stress has been shown, only recently, at the level of a single rough fracture [1]. Here, we investigate the impact of geologic (tectonic) stress on flow and tracer transport through natural fracture networks. We model geomechanical effects in 2D fractured rock by means of a finite-discrete element method (FEMDEM) [2], which can capture the deformation of matrix blocks, reactivation of pre-existing fractures, and propagation of new cracks, upon changes in the stress field. We apply the model to a fracture network extracted from the geological map of an actual rock outcrop to obtain the aperture field at different stress conditions. We then simulate fluid flow and particle transport through the stressed fracture networks. We observe that anomalous transport emerges in response to confining stress on the fracture network, and show that the stress state is a powerful determinant of transport behavior: (1) An anisotropic stress state induces preferential flow paths through shear dilation; (2) An increase in geologic stress increases aperture heterogeneity that induces late-time tailing of particle breakthrough curves. Finally, we develop an effective transport model that captures the anomalous transport through the stressed fracture network. Our results point to a heretofore unrecognized link between geomechanics and anomalous transport in natural fractured media. [1] P. K. Kang, S. Brown, and R. Juanes, Earth and Planetary Science Letters, 454, 46-54 (2016). [2] Q. Lei, J. P. Latham, and C. F. Tsang, Computers and Geotechnics, 85, 151-176 (2017).

The human coronary vasodilatory response to acute mental stress is mediated by neuronal nitric oxide synthase.

PubMed

Khan, Sitara G; Melikian, Narbeh; Shabeeh, Husain; Cabaco, Ana R; Martin, Katherine; Khan, Faisal; O'Gallagher, Kevin; Chowienczyk, Philip J; Shah, Ajay M

2017-09-01

Mental stress-induced ischemia approximately doubles the risk of cardiac events in patients with coronary artery disease, yet the mechanisms underlying changes in coronary blood flow in response to mental stress are poorly characterized. Neuronal nitric oxide synthase (nNOS) regulates basal coronary blood flow in healthy humans and mediates mental stress-induced vasodilation in the forearm. However, its possible role in mental stress-induced increases in coronary blood flow is unknown. We studied 11 patients (6 men and 5 women, mean age: 58 ± 14 yr) undergoing elective diagnostic cardiac catheterization and assessed the vasodilator response to mental stress elicited by the Stroop color-word test. Intracoronary substance P (20 pmol/min) and isosorbide dinitrate (1 mg) were used to assess endothelium-dependent and -independent vasodilation, respectively. Coronary blood flow was estimated using intracoronary Doppler recordings and quantitative coronary angiography to measure coronary artery diameter. Mental stress increased coronary flow by 34 ± 7.0% over the preceding baseline during saline infusion ( P < 0.01), and this was reduced to 26 ± 7.0% in the presence of the selective nNOS inhibitor S -methyl-l-thiocitrulline (0.625 µmol/min, P < 0.001). Mental stress increased coronary artery diameter by 6.9 ± 3.7% ( P = 0.02) and 0.5 ± 2.8% ( P = 0.51) in the presence of S -methyl-l-thiocitrulline. The response to substance P did not predict the response to mental stress ( r 2 = -0.22, P = 0.83). nNOS mediates the human coronary vasodilator response to mental stress, predominantly through actions at the level of coronary resistance vessels. NEW & NOTEWORTHY Acute mental stress induces vasodilation of the coronary microvasculature. Here, we show that this response involves neuronal nitric oxide synthase in the human coronary circulation.Listen to this article's corresponding podcast at http://ajpheart.podbean.com/e/nnos-and-coronary-flow-during-mental-stress/. Copyright © 2017 the American Physiological Society.

The human coronary vasodilatory response to acute mental stress is mediated by neuronal nitric oxide synthase

PubMed Central

Khan, Sitara G.; Melikian, Narbeh; Shabeeh, Husain; Cabaco, Ana R.; Martin, Katherine; Khan, Faisal; O’Gallagher, Kevin; Chowienczyk, Philip J.

2017-01-01

Mental stress-induced ischemia approximately doubles the risk of cardiac events in patients with coronary artery disease, yet the mechanisms underlying changes in coronary blood flow in response to mental stress are poorly characterized. Neuronal nitric oxide synthase (nNOS) regulates basal coronary blood flow in healthy humans and mediates mental stress-induced vasodilation in the forearm. However, its possible role in mental stress-induced increases in coronary blood flow is unknown. We studied 11 patients (6 men and 5 women, mean age: 58 ± 14 yr) undergoing elective diagnostic cardiac catheterization and assessed the vasodilator response to mental stress elicited by the Stroop color-word test. Intracoronary substance P (20 pmol/min) and isosorbide dinitrate (1 mg) were used to assess endothelium-dependent and -independent vasodilation, respectively. Coronary blood flow was estimated using intracoronary Doppler recordings and quantitative coronary angiography to measure coronary artery diameter. Mental stress increased coronary flow by 34 ± 7.0% over the preceding baseline during saline infusion (P < 0.01), and this was reduced to 26 ± 7.0% in the presence of the selective nNOS inhibitor S-methyl-l-thiocitrulline (0.625 µmol/min, P < 0.001). Mental stress increased coronary artery diameter by 6.9 ± 3.7% (P = 0.02) and 0.5 ± 2.8% (P = 0.51) in the presence of S-methyl-l-thiocitrulline. The response to substance P did not predict the response to mental stress (r2 = −0.22, P = 0.83). nNOS mediates the human coronary vasodilator response to mental stress, predominantly through actions at the level of coronary resistance vessels. NEW & NOTEWORTHY Acute mental stress induces vasodilation of the coronary microvasculature. Here, we show that this response involves neuronal nitric oxide synthase in the human coronary circulation. Listen to this article’s corresponding podcast at http://ajpheart.podbean.com/e/nnos-and-coronary-flow-during-mental-stress/. PMID:28646032

Approaches to modelling hydrology and ecosystem interactions

NASA Astrophysics Data System (ADS)

Silberstein, Richard P.

2014-05-01

As the pressures of industry, agriculture and mining on groundwater resources increase there is a burgeoning un-met need to be able to capture these multiple, direct and indirect stresses in a formal framework that will enable better assessment of impact scenarios. While there are many catchment hydrological models and there are some models that represent ecological states and change (e.g. FLAMES, Liedloff and Cook, 2007), these have not been linked in any deterministic or substantive way. Without such coupled eco-hydrological models quantitative assessments of impacts from water use intensification on water dependent ecosystems under changing climate are difficult, if not impossible. The concept would include facility for direct and indirect water related stresses that may develop around mining and well operations, climate stresses, such as rainfall and temperature, biological stresses, such as diseases and invasive species, and competition such as encroachment from other competing land uses. Indirect water impacts could be, for example, a change in groundwater conditions has an impact on stream flow regime, and hence aquatic ecosystems. This paper reviews previous work examining models combining ecology and hydrology with a view to developing a conceptual framework linking a biophysically defensable model that combines ecosystem function with hydrology. The objective is to develop a model capable of representing the cumulative impact of multiple stresses on water resources and associated ecosystem function.

Reynolds stress flow shear and turbulent energy transfer in reversed field pinch configuration

NASA Astrophysics Data System (ADS)

Vianello, Nicola; Spolaore, Monica; Serianni, Gianluigi; Regnoli, Giorgio; Spada, Emanuele; Antoni, Vanni; Bergsåker, Henric; Drake, James R.

2003-10-01

The role of Reynolds Stress tensor on flow generation in turbulent fluids and plasmas is still an open question and the comprehension of its behavior may assist the understanding of improved confinement scenario. It is generally believed that shear flow generation may occur by an interaction of the turbulent Reynolds stress with the shear flow. It is also generally believed that this mechanism may influence the generation of zonal flow shears. The evaluation of the complete Reynolds Stress tensor requires contemporary measurements of its electrostatic and magnetic part: this requirement is more restrictive for Reversed Field Pinch configuration where magnetic fluctuations are larger than in tokamak . A new diagnostic system which combines electrostatic and magnetic probes has been installed in the edge region of Extrap-T2R reversed field pinch. With this new probe the Reynolds stress tensor has been deduced and its radial profile has been reconstructed on a shot to shot basis exploring differen plasma conditions. These profiles have been compared with the naturally occurring velocity flow profile, in particular during Pulsed Poloidal Current Drive experiment, where a strong variation of ExB flow radial profile has been registered. The study of the temporal evolution of Reynolds stress reveals the appearance of strong localized bursts: these are considered in relation with global MHD relaxation phenomena, which naturally occur in the core of an RFP plasma sustaining its configuration.

The effect of light level, CO2 flow rate, and anesthesia on the stress response of mice during CO2 euthanasia.

PubMed

Powell, Karin; Ethun, Kelly; Taylor, Douglas K

2016-09-21

Euthanasia protocols are designed to mitigate the stress experienced by animals, and an environment that induces minimal stress helps achieve that goal. A protocol that is efficient and practical in a typical animal research facility is also important. Light intensity, isoflurane, and CO2 flow rate were studied for their impact on the stress response of mice during CO2 euthanasia. Behavior was observed and scored during euthanasia and serum corticosterone was measured immediately after death. Unsurprisingly, animals euthanized with a high-flow rate of CO2 became unconscious in the least amount of time, while animals euthanized with a low-flow rate required the most time to reach unconsciousness. There was a significant increase in anxious behaviors in animals in the isoflurane group (F1,12 = 6.67, P = 0.024), the high-flow rate CO2 group (F1,12 = 10.24, P = 0.007), and bright chamber group (F1,12 = 7.27, P = 0.019). Serum corticosterone was highest in the isoflurane group (124.72 ± 83.98 ng/ml), however there was no significant difference in corticosterone levels observed for the other study variables of light and flow-rate. A darkened chamber and low CO2 flow rates help to decrease stress experienced during CO2 euthanasia, while the use of isoflurane was observed to increase the stress response during euthanasia.

Role of endothelium sensitivity to shear stress in noradrenaline-induced constriction of feline femoral arterial bed under constant flow and constant pressure perfusions.

PubMed

Kartamyshev, Sergey P; Balashov, Sergey A; Melkumyants, Arthur M

2007-01-01

The effect of shear stress at the endothelium in the attenuation of the noradrenaline-induced constriction of the femoral vascular bed perfused at a constant blood flow was investigated in 16 anesthetized cats. It is known that the adrenergic vasoconstriction of the femoral vascular bed is considerably greater at a constant pressure perfusion than at a constant blood flow. This difference may depend on the ability of the endothelium to relax smooth muscle in response to an increase in wall shear stress. Since the shear stress is directly related to the blood flow and inversely related to the third power of vessel diameter, vasoconstriction at a constant blood flow increases the wall shear stress that is the stimulus for smooth muscle relaxation opposing constriction. On the other hand, at a constant perfusion pressure, vasoconstriction is accompanied by a decrease in flow rate, which prevents a wall shear stress increase. To reveal the effect of endothelial sensitivity to shear stress, we compared noradrenaline-induced changes in total and proximal arterial resistances during perfusion of the hind limb at a constant blood flow and at a constant pressure in vessels with intact and injured endothelium. We found that in the endothelium-intact bed the same concentration of noradrenaline at a constant flow caused an increase in overall vascular peripheral resistance that was half as large as at a constant perfusion pressure. This difference is mainly confined to the proximal arterial vessels (arteries and large arterioles) whose resistance at a constant flow increased only 0.19 +/- 0.03 times compared to that at a constant pressure. The removal of the endothelium only slightly increased constrictor responses at the perfusion under a constant pressure (noradrenaline-induced increases of both overall and proximal arterial resistance augmented by 12%), while the responses of the proximal vessels at a constant flow became 4.7 +/- 0.4 times greater than in the endothelium-intact bed. A selective blockage of endothelium sensitivity to shear stress using a glutaraldehyde dimer augmented the constrictor responses of the proximal vessels at a constant flow 4.6-fold (+/-0.3), but had no significant effect on the responses at a constant pressure. These results are consistent with the conclusion that the difference in constrictor responses at constant flow and pressure perfusions depends mainly on the smooth muscle relaxation caused by increased wall shear stress. Copyright (c) 2007 S. Karger AG, Basel.

Shear stress induced stimulation of mammalian cell metabolism

NASA Technical Reports Server (NTRS)

Mcintire, L. V.; Frangos, J. A.; Eskin, S. G.

1988-01-01

A flow apparatus was developed for the study of the metabolic response of anchorage dependent cells to a wide range of steady and pulsatile shear stresses under well controlled conditions. Human umbilical vein endothelial cell monolayers were subjected to steady shear stresses of up to 24 dynes/sq cm, and the production of prostacyclin was determined. The onset of flow led to a burst in prostacyclin production which decayed to a long term steady state rate (SSR). The SSR of cells exposed to flow was greater than the basal release level, and increased linearly with increasing shear stress. It is demonstrated that shear stresses in certain ranges may not be detrimental to mammalian cell metabolism. In fact, throughout the range of shear stresses studied, metabolite production is maximized by maximizing shear stress.

Flow dependence of forearm noradrenaline overflow, as assessed during mental stress and sodium nitroprusside infusion.

PubMed

Lindqvist, M; Melcher, A; Hjemdahl, P

1999-01-01

To evaluate the influence of blood flow on measurements of regional sympathetic nerve activity by radiotracer methodology ([3H]noradrenaline). Ten healthy men were studied under two conditions of elevated forearm blood flow: mental stress (Stroop colour word conflict test) and an intra-arterial infusion of sodium nitroprusside. Arterial blood pressure was measured invasively and forearm blood flow with strain-gauge plethysmography. Arterial and venous plasma adrenaline and noradrenaline were measured with high-performance liquid chromatography, and regional and total noradrenaline spillover were calculated. During mental stress, mean arterial pressure increased by 17%, heart rate by 16 beats/min, forearm blood flow by 117%, while forearm vascular resistance decreased by 44% (P < 0.001 for all). Sodium nitroprusside increased forearm blood flow dose-dependently, but elicited only minor effects on systemic haemodynamics. Mental stress increased arterial plasma noradrenaline by 52% (P < 0.001), and total body noradrenaline spillover by 75% (P < 0.001). During sodium nitroprusside infusion, arterial plasma noradrenaline increased only slightly and total body noradrenaline spillover was unaffected Forearm noradrenaline overflow increased from 5.4 +/- 0.9 to 16.9 +/- 2.6 pmol/min per I (P < 0.001) during mental stress and from 6.6 +/- 0.8 to 16.9 +/- 3.7 pmol/min per I (P < 0.001) during the second dose-step of sodium nitroprusside infusion. By intra-individual comparisons of forearm noradrenaline overflow increases during mental stress and during sodium nitroprusside infusion, with similar forearm blood flow increases, the flow dependence of forearm noradrenaline overflow was estimated. During mental stress, about 60% (median value, range 29-112%) of the increase in forearm noradrenaline overflow was attributed to the increase in forearm blood flow, whereas 40% was considered to reflect increased sympathetic nerve activity. There seems to be a considerable flow dependence of the regional overflow of noradrenaline, that is, a component of simple wash-out of noradrenaline from the forearm tissues during vasodilation. However, the present results still indicate that sympathetic nerve activity in the forearm is increased during mental stress, justifying the radiotracer technique for semiquantitative measurements, also during vasodilation.

The future of irrigated agriculture under environmental flow requirements restrictions

NASA Astrophysics Data System (ADS)

Pastor, Amandine; Palazzo, Amanda; Havlik, Petr; Kabat, Pavel; Obersteiner, Michael; Ludwig, Fulco

2016-04-01

Water is not an infinite resource and demand from irrigation, household and industry is constantly increasing. This study focused on including global water availability including environmental flow requirements with water withdrawal from irrigation and other sectors at a monthly time-step in the GLOBIOM model. This model allows re-adjustment of land-use allocation, crop management, consumption and international trade. The GLOBIOM model induces an endogenous change in water price depending on water supply and demand. In this study, the focus was on how the inclusion of water resources affects land-use and, in particular, how global change will influence repartition of irrigated and rainfed lands at global scale. We used the climate change scenario including a radiative forcing of 8.5 W/m2 (RCP8.5), the socio-economic scenario (SSP2: middle-of-road), and the environmental flow method based on monthly flow allocation (the Variable Monthly Flow method) with high and low restrictions. Irrigation withdrawals were adjusted to a monthly time-step to account for biophysical water limitations at finer time resolution. Our results show that irrigated land might decrease up to 40% on average depending on the choice of EFR restrictions. Several areas were identified as future hot-spots of water stress such as the Mediterranean and Middle-East regions. Other countries were identified to be in safe position in terms of water stress such as North-European countries. Re-allocation of rainfed and irrigated land might be useful information for land-use planners and water managers at an international level to decide on appropriate legislations on climate change mitigation/adaptation when exposure and sensitivity to climate change is high and/or on adaptation measures to face increasing water demand. For example, some countries are likely to adopt measures to increase their water use efficiencies (irrigation system, soil and water conservation practices) to face water shortages, while others might consider improving their trade policy to avoid food shortage.

POD analysis of flow over a backward-facing step forced by right-angle-shaped plasma actuator.

PubMed

Wang, Bin; Li, Huaxing

2016-01-01

This study aims to present flow control over the backward-facing step with specially designed right-angle-shaped plasma actuator and analyzed the influence of various scales of flow structures on the Reynolds stress through snapshot proper orthogonal decomposition (POD). 2D particle image velocimetry measurements were conducted on region (x/h = 0-2.25) and reattachment zone in the x-y plane over the backward-facing step at a Reynolds number of Re h  = 27,766 (based on step height [Formula: see text] and free stream velocity [Formula: see text]. The separated shear layer was excited by specially designed right-angle-shaped plasma actuator under the normalized excitation frequency St h  ≈ 0.345 along the 45° direction. The spatial distribution of each Reynolds stress component was reconstructed using an increasing number of POD modes. The POD analysis indicated that the flow dynamic downstream of the step was dominated by large-scale flow structures, which contributed to streamwise Reynolds stress and Reynolds shear stress. The intense Reynolds stress localized to a narrow strip within the shear layer was mainly affected by small-scale flow structures, which were responsible for the recovery of the Reynolds stress peak. With plasma excitation, a significant increase was obtained in the vertical Reynolds stress peak. Under the dimensionless frequencies St h  ≈ 0.345 and [Formula: see text] which are based on the step height and momentum thickness, the effectiveness of the flow control forced by the plasma actuator along the 45° direction was ordinary. Only the vertical Reynolds stress was significantly affected.

Hydrodynamics, wall-slip, and normal-stress differences in rarefied granular Poiseuille flow

NASA Astrophysics Data System (ADS)

Gupta, Ronak; Alam, Meheboob

2017-02-01

Hydrodynamic fields, macroscopic boundary conditions, and non-Newtonian rheology of the acceleration-driven Poiseuille flow of a dilute granular gas are probed using "direct simulation Monte Carlo" method for a range of Knudsen numbers (Kn, the ratio between the mean free path and the macroscopic length), spanning the rarefied regime of slip and transitional flows. It is shown that the "dissipation-induced clustering" (for 1 -en>0 , where en is the restitution coefficient), leading to inhomogeneous density profiles along the transverse direction, competes with "rarefaction-induced declustering" (for Kn>0 ) phenomenon, leaving seemingly "anomalous" footprints on several hydrodynamic and rheological quantities; one example is the well-known rarefaction-induced temperature bimodality, which could also result from inelastic dissipation that dominates in the continuum limit (Kn→0 ) as found recently [Alam et al., J. Fluid Mech. 782, 99 (2015), 10.1017/jfm.2015.523]. The simulation data on the slip velocity and the temperature slip are contrasted with well-established boundary conditions for molecular gases. A modified Maxwell-Navier-type boundary condition is found to hold in granular Poiseuille flow, with the velocity slip length following a power-law relation with Knudsen number Knδ, with δ ≈0.95 , for Kn≤0.1 . Transverse profiles of both first [N1(y ) ] and second [N2(y ) ] normal stress differences seem to correlate well with respective density profiles at small Kn; their centerline values [N1(0 ) and N2(0 ) ] can be of "odd" sign with respect to their counterparts in molecular gases. The phase diagrams are constructed in the (Kn,1 -en ) plane that demarcates the regions of influence of inelasticity and rarefaction, which compete with each other resulting in the sign change of both N1(0 ) and N2(0 ) . The results on normal stress differences are rationalized via a comparison with a Burnett-order theory [Sela and Goldhirsch, J. Fluid Mech. 361, 41 (1998), 10.1017/S0022112098008660], which is able to predict their correct behavior at small values of the Knudsen number. Lastly, the Knudsen paradox and its dependence on inelasticity are analyzed and contrasted with related recent works.

Generation of parasitic axial flow by drift wave turbulence with broken symmetry: Theory and experiment

NASA Astrophysics Data System (ADS)

Hong, R.; Li, J. C.; Hajjar, R.; Chakraborty Thakur, S.; Diamond, P. H.; Tynan, G. R.

2018-05-01

Detailed measurements of intrinsic axial flow generation parallel to the magnetic field in the controlled shear decorrelation experiment linear plasma device with no axial momentum input are presented and compared to theory. The results show a causal link from the density gradient to drift-wave turbulence with broken spectral symmetry and development of the axial mean parallel flow. As the density gradient steepens, the axial and azimuthal Reynolds stresses increase and radially sheared azimuthal and axial mean flows develop. A turbulent axial momentum balance analysis shows that the axial Reynolds stress drives the radially sheared axial mean flow. The turbulent drive (Reynolds power) for the azimuthal flow is an order of magnitude greater than that for axial flow, suggesting that the turbulence fluctuation levels are set by azimuthal flow shear regulation. The direct energy exchange between axial and azimuthal mean flows is shown to be insignificant. Therefore, the axial flow is parasitic to the turbulence-zonal flow system and is driven primarily by the axial turbulent stress generated by that system. The non-diffusive, residual part of the axial Reynolds stress is found to be proportional to the density gradient and is formed due to dynamical asymmetry in the drift-wave turbulence.

Thermal Stress and Toxicity | Science Inventory | US EPA

EPA Pesticide Factsheets

Elevating ambient temperature above thermoneutrality exacerbates toxicity of most air pollutants, insecticides, and other toxic chemicals. On the other hand, safety and toxicity testing of toxicants and drugs is usually performed in mice and rats maintained at subthermoneutral temperatures of —22 °C. When exposed to chemical toxicants under these relatively cool conditions, rodents typically undergo a regulated hypothermic response, characterized by preference for cooler ambient temperatures and controlled reduction in core temperature. Reducing core temperature delays the clearance of most toxicants from the body; however, a mild hypothermia also improves recovery and survival from the toxicant. Raising ambient temperature to thermoneutrality and above increases the rate of clearance of the toxicant but also exacerbates toxicity. Furthermore, heat stress combined with work or exercise is likely to worsen toxicity. Body temperature of large mammals, including humans, does not decrease as much in response to exposure to a toxicant. However, heat stress tan nonetheless worsen toxic outcome in humans through a variety of mechanisms. For example, heat-induced sweating and elevation in skin blood flow accelerates uptake of some insecticides. Epidemiological studies suggest that thermal stress may exacerbate the toxicity of airborne pollutants such as ozone and particulate matter. Overall, translating results of studies in rodents to that of humans is a formidable

Animal models of surgically manipulated flow velocities to study shear stress-induced atherosclerosis.

PubMed

Winkel, Leah C; Hoogendoorn, Ayla; Xing, Ruoyu; Wentzel, Jolanda J; Van der Heiden, Kim

2015-07-01

Atherosclerosis is a chronic inflammatory disease of the arterial tree that develops at predisposed sites, coinciding with locations that are exposed to low or oscillating shear stress. Manipulating flow velocity, and concomitantly shear stress, has proven adequate to promote endothelial activation and subsequent plaque formation in animals. In this article, we will give an overview of the animal models that have been designed to study the causal relationship between shear stress and atherosclerosis by surgically manipulating blood flow velocity profiles. These surgically manipulated models include arteriovenous fistulas, vascular grafts, arterial ligation, and perivascular devices. We review these models of manipulated blood flow velocity from an engineering and biological perspective, focusing on the shear stress profiles they induce and the vascular pathology that is observed. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Parameters of Blood Flow in Great Arteries in Hypertensive ISIAH Rats with Stress-Dependent Arterial Hypertension.

PubMed

Seryapina, A A; Shevelev, O B; Moshkin, M P; Markel', A L

2016-08-01

Magnetic resonance angiography was used to examine blood flow in great arteries of hypertensive ISIAH and normotensive Wistar rats. In hypertensive ISIAH rats, increased vascular resistance in the basin of the abdominal aorta and renal arteries as well as reduced fraction of total renal blood flow were found. In contrast, blood flow through both carotid arteries in ISIAH rats was enhanced, which in suggests more intensive blood supply to brain regulatory centers providing enhanced stress reactivity of these rats characterized by stress-dependent arterial hypertension.

On the large eddy simulation of turbulent flows in complex geometry

NASA Technical Reports Server (NTRS)

Ghosal, Sandip

1993-01-01

Application of the method of Large Eddy Simulation (LES) to a turbulent flow consists of three separate steps. First, a filtering operation is performed on the Navier-Stokes equations to remove the small spatial scales. The resulting equations that describe the space time evolution of the 'large eddies' contain the subgrid-scale (sgs) stress tensor that describes the effect of the unresolved small scales on the resolved scales. The second step is the replacement of the sgs stress tensor by some expression involving the large scales - this is the problem of 'subgrid-scale modeling'. The final step is the numerical simulation of the resulting 'closed' equations for the large scale fields on a grid small enough to resolve the smallest of the large eddies, but still much larger than the fine scale structures at the Kolmogorov length. In dividing a turbulent flow field into 'large' and 'small' eddies, one presumes that a cut-off length delta can be sensibly chosen such that all fluctuations on a scale larger than delta are 'large eddies' and the remainder constitute the 'small scale' fluctuations. Typically, delta would be a length scale characterizing the smallest structures of interest in the flow. In an inhomogeneous flow, the 'sensible choice' for delta may vary significantly over the flow domain. For example, in a wall bounded turbulent flow, most statistical averages of interest vary much more rapidly with position near the wall than far away from it. Further, there are dynamically important organized structures near the wall on a scale much smaller than the boundary layer thickness. Therefore, the minimum size of eddies that need to be resolved is smaller near the wall. In general, for the LES of inhomogeneous flows, the width of the filtering kernel delta must be considered to be a function of position. If a filtering operation with a nonuniform filter width is performed on the Navier-Stokes equations, one does not in general get the standard large eddy equations. The complication is caused by the fact that a filtering operation with a nonuniform filter width in general does not commute with the operation of differentiation. This is one of the issues that we have looked at in detail as it is basic to any attempt at applying LES to complex geometry flows. Our principal findings are summarized.

A study on the uniqueness of the plastic flow direction for granular assemblies of ductile particles using discrete finite-element simulations

NASA Astrophysics Data System (ADS)

Abdelmoula, Nouha; Harthong, Barthélémy; Imbault, Didier; Dorémus, Pierre

2017-12-01

The multi-particle finite element method involving assemblies of meshed particles interacting through finite-element contact conditions is adopted to study the plastic flow of a granular material with highly deformable elastic-plastic grains. In particular, it is investigated whether the flow rule postulate applies for such materials. Using a spherical stress probing method, the influence of incremental stress on plastic strain increment vectors was assessed for numerical samples compacted along two different loading paths up to different values of relative density. Results show that the numerical samples studied behave reasonably well according to an associated flow rule, except in the vicinity of the loading point where the influence of the stress increment proved to be very significant. A plausible explanation for the non-uniqueness of the direction of plastic flow is proposed, based on the idea that the resistance of the numerical sample to plastic straining can vary by an order of magnitude depending on the direction of the accumulated stress. The above-mentioned dependency of the direction of plastic flow on the direction of the stress increment was related to the difference in strength between shearing and normal stressing at the scale of contact surfaces between particles.

Contribution of microreactor technology and flow chemistry to the development of green and sustainable synthesis.

PubMed

Fanelli, Flavio; Parisi, Giovanna; Degennaro, Leonardo; Luisi, Renzo

2017-01-01

Microreactor technology and flow chemistry could play an important role in the development of green and sustainable synthetic processes. In this review, some recent relevant examples in the field of flash chemistry, catalysis, hazardous chemistry and continuous flow processing are described. Selected examples highlight the role that flow chemistry could play in the near future for a sustainable development.

A test of the double-shearing model of flow for granular materials

USGS Publications Warehouse

Savage, J.C.; Lockner, D.A.

1997-01-01

The double-shearing model of flow attributes plastic deformation in granular materials to cooperative slip on conjugate Coulomb shears (surfaces upon which the Coulomb yield condition is satisfied). The strict formulation of the double-shearing model then requires that the slip lines in the material coincide with the Coulomb shears. Three different experiments that approximate simple shear deformation in granular media appear to be inconsistent with this strict formulation. For example, the orientation of the principal stress axes in a layer of sand driven in steady, simple shear was measured subject to the assumption that the Coulomb failure criterion was satisfied on some surfaces (orientation unspecified) within the sand layer. The orientation of the inferred principal compressive axis was then compared with the orientations predicted by the double-shearing model. The strict formulation of the model [Spencer, 1982] predicts that the principal stress axes should rotate in a sense opposite to that inferred from the experiments. A less restrictive formulation of the double-shearing model by de Josselin de Jong [1971] does not completely specify the solution but does prescribe limits on the possible orientations of the principal stress axes. The orientations of the principal compression axis inferred from the experiments are probably within those limits. An elastoplastic formulation of the double-shearing model [de Josselin de Jong, 1988] is reasonably consistent with the experiments, although quantitative agreement was not attained. Thus we conclude that the double-shearing model may be a viable law to describe deformation of granular materials, but the macroscopic slip surfaces will not in general coincide with the Coulomb shears.

Observations of instability, hysteresis, and oscillation in low-Reynolds-number flow past polymer gels.

PubMed

Eggert, Matthew D; Kumar, Satish

2004-10-01

We perform a set of experiments to study the nonlinear nature of an instability that arises in low-Reynolds-number flow past polymer gels. A layer of a viscous liquid is placed on a polydimethylsiloxane (PDMS) gel in a parallel-plate rheometer which is operated in stress-controlled mode. As the shear stress on the top plate increases, the apparent viscosity stays relatively constant until a transition stress where it sharply increases. If the stress is held at a level slightly above the transition stress, the apparent viscosity oscillates with time. If the stress is increased to a value above the transition stress and then decreased back to zero, the apparent viscosity shows hysteretic behavior. If the stress is instead decreased to a constant value and held there, the apparent viscosity is different from its pretransition value and exhibits sustained oscillations. This can happen even if the stress is held at values below the transition stress. Our observations suggest that the instability studied here is subcritical and leads to a flow that is oscillatory and far from viscometric. The phenomena reported here may be useful in applications such as microfluidics, membrane separations, and polymer processing. They may also provide insight into the rheological behavior of complex fluids that undergo flow-induced gelation.

Comprehensive Forced Response Analysis of J2X Turbine Bladed-Discs with 360 Degree Variation in CFD Loading

NASA Technical Reports Server (NTRS)

Elrod, David; Christensen, Eric; Brown, Andrew

2011-01-01

The temporal frequency content of the dynamic pressure predicted by a 360 degree computational fluid dynamics (CFD) analysis of a turbine flow field provides indicators of forcing function excitation frequencies (e.g., multiples of blade pass frequency) for turbine components. For the Pratt and Whitney Rocketdyne J-2X engine turbopumps, Campbell diagrams generated using these forcing function frequencies and the results of NASTRAN modal analyses show a number of components with modes in the engine operating range. As a consequence, forced response and static analyses are required for the prediction of combined stress, high cycle fatigue safety factors (HCFSF). Cyclically symmetric structural models have been used to analyze turbine vane and blade rows, not only in modal analyses, but also in forced response and static analyses. Due to the tortuous flow pattern in the turbine, dynamic pressure loading is not cyclically symmetric. Furthermore, CFD analyses predict dynamic pressure waves caused by adjacent and non-adjacent blade/vane rows upstream and downstream of the row analyzed. A MATLAB script has been written to calculate displacements due to the complex cyclically asymmetric dynamic pressure components predicted by CFD analysis, for all grids in a blade/vane row, at a chosen turbopump running speed. The MATLAB displacements are then read into NASTRAN, and dynamic stresses are calculated, including an adjustment for possible mistuning. In a cyclically symmetric NASTRAN static analysis, static stresses due to centrifugal, thermal, and pressure loading at the mode running speed are calculated. MATLAB is used to generate the HCFSF at each grid in the blade/vane row. When compared to an approach assuming cyclic symmetry in the dynamic flow field, the current approach provides better assurance that the worst case safety factor has been identified. An extended example for a J-2X turbopump component is provided.

Evaluation of geophysical mass flow models using the 2006 block-and-ash flows of Merapi Volcano, Java, Indonesia: Towards a short-term hazard assessment tool

NASA Astrophysics Data System (ADS)

Charbonnier, S. J.; Gertisser, R.

2012-06-01

The dynamics and depositional processes associated with block-and-ash flows (BAFs) are most commonly inferred to be a function of granular or inertial grain flow, similar to debris flows and cold rock avalanches. Existing geophysical mass flow models are either based on frictional (Mohr-Coulomb) behavior (the Titan2D model developed at the State University of New York at Buffalo, USA) or another rheological law (i.e., a constant retarding stress), eventually adding some viscous and turbulent components (the VolcFlow model developed at the Laboratoire Magmas et Volcans, Clermont-Ferrand, France). The 2006 BAFs of Merapi present a rare opportunity to test these two well-established models against a well-constrained field example. Integration of high-resolution field-based data into numerical simulations allows the validity of these models to be tested and rapid quantification of best-fit input parameters. We first show that with the incorporation of spatially varying bed friction angles, Titan2D is capable of reproducing the paths, runout distances, areas covered and deposited volumes of the 2006 Merapi flows over highly complex topography. However, some discrepancies with field data are noted and the velocity and travel time of the flows do not match entirely. Using a single free parameter (a constant retarding stress), simulations obtained with the VolcFlow model also reproduce the morphology and distribution of the natural deposits as well as the time of emplacement and velocities of the flows. The results suggest that the performance of these models in simulating actual events is critically dependent on: (1) the calibration of the model by using extensive field-based data such as deposit distribution, and processes of flow generation, transport and deposition; (2) the incorporation of a suitable numerical topographic dataset (i.e., high-resolution digital elevation model), and (3) the choice of input parameters, such as location and volume of the initial pile of material and source characteristics (single or multiple dome-collapse, dome-collapse duration and total volume of collapsed material). Sensitivity analyses and inundation maps based on the probability of impact were used to produce a suite of potentially inundated areas from future gravitational dome-collapse events affecting the Gendol valley and adjacent areas on the southern flank of the volcano. Our results provide the basis for defining hazard zonations of key areas at risk from BAFs which will be generated during future comparable eruptions at Merapi.

Bellows flow-induced vibrations

NASA Technical Reports Server (NTRS)

Tygielski, P. J.; Smyly, H. M.; Gerlach, C. R.

1983-01-01

The bellows flow excitation mechanism and results of comprehensive test program are summarized. The analytical model for predicting bellows flow induced stress is refined. The model includes the effects of an upstream elbow, arbitrary geometry, and multiple piles. A refined computer code for predicting flow induced stress is described which allows life prediction if a material S-N diagram is available.

Aerodynamic surface stress intermittency and conditionally averaged turbulence statistics

NASA Astrophysics Data System (ADS)

Anderson, William; Lanigan, David

2015-11-01

Aeolian erosion is induced by aerodynamic stress imposed by atmospheric winds. Erosion models prescribe that sediment flux, Q, scales with aerodynamic stress raised to exponent, n, where n > 1 . Since stress (in fully rough, inertia-dominated flows) scales with incoming velocity squared, u2, it follows that q ~u2n (where u is some relevant component of the flow). Thus, even small (turbulent) deviations of u from its time-mean may be important for aeolian activity. This rationale is augmented given that surface layer turbulence exhibits maximum Reynolds stresses in the fluid immediately above the landscape. To illustrate the importance of stress intermittency, we have used conditional averaging predicated on stress during large-eddy simulation of atmospheric boundary layer flow over an arid, bare landscape. Conditional averaging provides an ensemble-mean visualization of flow structures responsible for erosion `events'. Preliminary evidence indicates that surface stress peaks are associated with the passage of inclined, high-momentum regions flanked by adjacent low-momentum regions. We characterize geometric attributes of such structures and explore streamwise and vertical vorticity distribution within the conditionally averaged flow field. This work was supported by the National Sci. Foundation, Phys. and Dynamic Meteorology Program (PM: Drs. N. Anderson, C. Lu, and E. Bensman) under Grant # 1500224. Computational resources were provided by the Texas Adv. Comp. Center at the Univ. of Texas.

Damped regional-scale stress inversions: Methodology and examples for southern California and the Coalinga aftershock sequence

USGS Publications Warehouse

Hardebeck, J.L.; Michael, A.J.

2006-01-01

We present a new focal mechanism stress inversion technique to produce regional-scale models of stress orientation containing the minimum complexity necessary to fit the data. Current practice is to divide a region into small subareas and to independently fit a stress tensor to the focal mechanisms of each subarea. This procedure may lead to apparent spatial variability that is actually an artifact of overfitting noisy data or nonuniquely fitting data that does not completely constrain the stress tensor. To remove these artifacts while retaining any stress variations that are strongly required by the data, we devise a damped inversion method to simultaneously invert for stress in all subareas while minimizing the difference in stress between adjacent subareas. This method is conceptually similar to other geophysical inverse techniques that incorporate damping, such as seismic tomography. In checkerboard tests, the damped inversion removes the stress rotation artifacts exhibited by an undamped inversion, while resolving sharper true stress rotations than a simple smoothed model or a moving-window inversion. We show an example of a spatially damped stress field for southern California. The methodology can also be used to study temporal stress changes, and an example for the Coalinga, California, aftershock sequence is shown. We recommend use of the damped inversion technique for any study examining spatial or temporal variations in the stress field.

Sustained expression of MCP-1 by low wall shear stress loading concomitant with turbulent flow on endothelial cells of intracranial aneurysm.

PubMed

Aoki, Tomohiro; Yamamoto, Kimiko; Fukuda, Miyuki; Shimogonya, Yuji; Fukuda, Shunichi; Narumiya, Shuh

2016-05-09

Enlargement of a pre-existing intracranial aneurysm is a well-established risk factor of rupture. Excessive low wall shear stress concomitant with turbulent flow in the dome of an aneurysm may contribute to progression and rupture. However, how stress conditions regulate enlargement of a pre-existing aneurysm remains to be elucidated. Wall shear stress was calculated with 3D-computational fluid dynamics simulation using three cases of unruptured intracranial aneurysm. The resulting value, 0.017 Pa at the dome, was much lower than that in the parent artery. We loaded wall shear stress corresponding to the value and also turbulent flow to the primary culture of endothelial cells. We then obtained gene expression profiles by RNA sequence analysis. RNA sequence analysis detected hundreds of differentially expressed genes among groups. Gene ontology and pathway analysis identified signaling related with cell division/proliferation as overrepresented in the low wall shear stress-loaded group, which was further augmented by the addition of turbulent flow. Moreover, expression of some chemoattractants for inflammatory cells, including MCP-1, was upregulated under low wall shear stress with concomitant turbulent flow. We further examined the temporal sequence of expressions of factors identified in an in vitro study using a rat model. No proliferative cells were detected, but MCP-1 expression was induced and sustained in the endothelial cell layer. Low wall shear stress concomitant with turbulent flow contributes to sustained expression of MCP-1 in endothelial cells and presumably plays a role in facilitating macrophage infiltration and exacerbating inflammation, which leads to enlargement or rupture.

Active chiral fluids.

PubMed

Fürthauer, S; Strempel, M; Grill, S W; Jülicher, F

2012-09-01

Active processes in biological systems often exhibit chiral asymmetries. Examples are the chirality of cytoskeletal filaments which interact with motor proteins, the chirality of the beat of cilia and flagella as well as the helical trajectories of many biological microswimmers. Here, we derive constitutive material equations for active fluids which account for the effects of active chiral processes. We identify active contributions to the antisymmetric part of the stress as well as active angular momentum fluxes. We discuss four types of elementary chiral motors and their effects on a surrounding fluid. We show that large-scale chiral flows can result from the collective behavior of such motors even in cases where isolated motors do not create a hydrodynamic far field.

Lubricant dynamics under sliding condition in disk drives

NASA Astrophysics Data System (ADS)

Wu, Lin

2006-07-01

In this paper, we develop a two-dimensional flow model for the lubricant flow dynamics under a sliding head in disk drives. Our two-dimensional model includes important physics such as viscous force, external air shearing stress, air bearing pressure, centrifugal force, disjoining pressure, and surface tension. Our analysis shows that the lubricant flow dynamics under the sliding condition is a fully two-dimensional phenomenon and the circumferential lubricant flow is strongly coupled to the radial flow. It is necessary to have a two-dimensional flow model that couples the circumferential and radial flows together and includes all important physics to achieve realistic predictions. Our results show that the external air shearing stress has a dominant effect on the lubricant flow dynamics. Both velocity slippage at wall and Poiseuille flow effects have to be considered in the evaluation of the air shearing stress under the head. The nonuniform air bearing pressure has a non-negligible effect on the lubricant film dynamics mostly through the Poiseuille flow effect on the air shearing stress but not from its direct pushing or sucking effect on the lubricant surface. Prediction of the formation of lubricant depletion tracks under a sliding head using the two-dimensional model agrees reasonably well with the existing experimental measurements.

Present-day stress field in subduction zones: Insights from 3D viscoelastic models and data

NASA Astrophysics Data System (ADS)

Petricca, Patrizio; Carminati, Eugenio

2016-01-01

3D viscoelastic FE models were performed to investigate the impact of geometry and kinematics on the lithospheric stress in convergent margins. Generic geometries were designed in order to resemble natural subduction. Our model predictions mirror the results of previous 2D models concerning the effects of lithosphere-mantle relative flow on stress regimes, and allow a better understanding of the lateral variability of the stress field. In particular, in both upper and lower plates, stress axes orientations depend on the adopted geometry and axes rotations occur following the trench shape. Generally stress axes are oriented perpendicular or parallel to the trench, with the exception of the slab lateral tips where rotations occur. Overall compression results in the upper plate when convergence rate is faster than mantle flow rate, suggesting a major role for convergence. In the slab, along-strike tension occurs at intermediate and deeper depths (> 100 km) in case of mantle flow sustaining the sinking lithosphere and slab convex geometry facing mantle flow or in case of opposing mantle flow and slab concave geometry facing mantle flow. Along-strike compression is predicted in case of sustaining mantle flow and concave slabs or in case of opposing mantle flow and convex slabs. The slab stress field is thus controlled by the direction of impact of mantle flow onto the slab and by slab longitudinal curvature. Slab pull produces not only tension in the bending region of subducted plate but also compression where upper and lower plates are coupled. A qualitative comparison between results and data in selected subductions indicates good match for South America, Mariana and Tonga-Kermadec subductions. Discrepancies, as for Sumatra-Java, emerge due to missing geometric (e.g., occurrence of fault systems and local changes in the orientation of plate boundaries) and rheological (e.g., plasticity associated with slab bending, anisotropy) complexities in the models.

Bed Surface Adjustments to Spatially Variable Flow in Low Relative Submergence Regimes

NASA Astrophysics Data System (ADS)

Monsalve, A.; Yager, E. M.

2017-11-01

In mountainous rivers, large relatively immobile grains partly control the local and reach-averaged flow hydraulics and sediment fluxes. When the flow depth is similar to the size of these grains (low relative submergence), heterogeneous flow structures and plunging flow cause spatial distributions of bed surface elevations, textures, and sedimentation rates. To explore how the bed surface responds to these flow variations we conducted a set of experiments in which we varied the relative submergence of staggered hemispheres (simulated large boulders) between runs. All experiments had the same average sediment transport capacity, upstream sediment supply, and initial bed thickness and grain size distribution. We combined our laboratory measurements with a 3-D flow model to obtain the detailed flow structure around the hemispheres. The local bed shear stress field displayed substantial variability and controlled the bed load transport rates and direction in which sediment moved. The divergence in bed shear stress caused by the hemispheres promoted size-selective bed load deposition, which formed patches of coarse sediment upstream of the hemisphere. Sediment deposition caused a decrease in local bed shear stress, which combined with the coarser grain size, enhanced the stability of this patch. The region downstream of the hemispheres was largely controlled by a recirculation zone and had little to no change in grain size, bed elevation, and bed shear stress. The formation, development, and stability of sediment patches in mountain streams is controlled by the bed shear stress divergence and magnitude and direction of the local bed shear stress field.

Molecular characteristics of stress overshoot for polymer melts under start-up shear flow.

PubMed

Jeong, Sohdam; Kim, Jun Mo; Baig, Chunggi

2017-12-21

Stress overshoot is one of the most important nonlinear rheological phenomena exhibited by polymeric liquids undergoing start-up shear at sufficient flow strengths. Despite considerable previous research, the fundamental molecular characteristics underlying stress overshoot remain unknown. Here, we analyze the intrinsic molecular mechanisms behind the overshoot phenomenon using atomistic nonequilibrium molecular dynamics simulations of entangled linear polyethylene melts under shear flow. Through a detailed analysis of the transient rotational chain dynamics, we identify an intermolecular collision angular regime in the vicinity of the chain orientation angle θ ≈ 20° with respect to the flow direction. The shear stress overshoot occurs via strong intermolecular collisions between chains in the collision regime at θ = 15°-25°, corresponding to a peak strain of 2-4, which is an experimentally well-known value. The normal stress overshoot appears at approximately θ = 10°, at a corresponding peak strain roughly equivalent to twice that for the shear stress. We provide plausible answers to several basic questions regarding the stress overshoot, which may further help understand other nonlinear phenomena of polymeric systems.

Flow cytometry enables identification of sporophytic eliciting stress treatments in gametic cells.

PubMed

Ribalta, F M; Croser, J S; Ochatt, S J

2012-01-01

Flow cytometry was used to quantify the effect of individual and combined stress treatments on elicitation of androgenesis by analyzing the relative nuclear DNA content of in vitro cultured microspores of Pisum sativum L. Differences in relative nuclear DNA content of microspores within anthers after stress treatments were clearly evident from the flow cytometry profiles, and permitted us to predict whether a combination of stresses were elicitors or enhancers of androgenesis. This is the first report to assess the effect of various stress treatments in a plant species based on relative nuclear DNA content and to use this information to categorize them as 'elicitors' or 'enhancers'. Flow cytometry represents a simple, quick and reliable way to analyze and discriminate the effect of various stress treatments on elicitation of androgenesis. These results form a solid basis for further efforts designed to enhance responses and to extend double haploid technology to other legumes. Copyright © 2011 Elsevier GmbH. All rights reserved.

Human endothelial cell responses to cardiovascular inspired pulsatile shear stress

NASA Astrophysics Data System (ADS)

Watson, Matthew; Baugh, Lauren; Black, Lauren, III; Kemmerling, Erica

2016-11-01

It is well established that hemodynamic shear stress regulates blood vessel structure and the development of vascular pathology. This process can be studied via in vitro models of endothelial cell responses to pulsatile shear stress. In this study, a macro-scale cone and plate viscometer was designed to mimic various shear stress waveforms found in the body and apply these stresses to human endothelial cells. The device was actuated by a PID-controlled DC gear-motor. Cells were exposed to 24 hours of pulsatile shear and then imaged and stained to track their morphology and secretions. These measurements were compared with control groups of cells exposed to constant shear and no shear. The results showed that flow pulsatility influenced levels of secreted proteins such as VE-cadherin and neuroregulin IHC. Cell morphology was also influenced by flow pulsatility; in general cells exposed to pulsatile shear stress developed a higher aspect ratio than cells exposed to no flow but a lower aspect ratio than cells exposed to steady flow.

Flow Behavior and Constitutive Equation of Ti-6.5Al-2Sn-4Zr-4Mo-1W-0.2Si Titanium Alloy

NASA Astrophysics Data System (ADS)

Yang, Xuemei; Guo, Hongzhen; Liang, Houquan; Yao, Zekun; Yuan, Shichong

2016-04-01

In order to get a reliable constitutive equation for the finite element simulation, flow behavior of Ti-6.5Al-2Sn-4Zr-4Mo-1W-0.2Si alloy under high temperature was investigated by carrying a series of isothermal compression tests at temperatures of 1153-1293 K and strain rates of 0.01-10.0 s-1 on the Gleeble-1500 simulator. Results showed that the true stress-strain curves exhibited peaks at small strains, after which the flow stress decreased monotonically. Ultimately, the flow curves reached steady state at the strain of 0.6, showing a dynamic flow softening phenomenon. The effects of strain rate, temperature, and strain on the flow behavior were researched by establishing a constitutive equation. The relations among stress exponent, deformation activation energy, and strain were preliminarily discussed by using strain rate sensitivity exponent and dynamic recrystallization kinetics curve. Stress values predicted by the modified constitutive equation showed a good agreement with the experimental ones. The correlation coefficient ( R) and average absolute relative error (AARE) were 98.2% and 4.88%, respectively, which confirmed that the modified constitutive equation could give an accurate estimation of the flow stress for BT25y titanium alloy.

Mathematical modeling of pulsatile flow of non-Newtonian fluid in stenosed arteries

NASA Astrophysics Data System (ADS)

Sankar, D. S.; Lee, Usik

2009-07-01

The pulsatile flow of blood through mild stenosed artery is studied. The effects of pulsatility, stenosis and non-Newtonian behavior of blood, treating the blood as Herschel-Bulkley fluid, are simultaneously considered. A perturbation method is used to analyze the flow. The expressions for the shear stress, velocity, flow rate, wall shear stress, longitudinal impedance and the plug core radius have been obtained. The variations of these flow quantities with different parameters of the fluid have been analyzed. It is found that, the plug core radius, pressure drop and wall shear stress increase with the increase of yield stress or the stenosis height. The velocity and the wall shear stress increase considerably with the increase in the amplitude of the pressure drop. It is clear that for a given value of stenosis height and for the increasing values of the stenosis shape parameter from 3 to 6, there is a sharp increase in the impedance of the flow and also the plots are skewed to the right-hand side. It is observed that the estimates of the increase in the longitudinal impedance increase with the increase of the axial distance or with the increase of the stenosis height. The present study also brings out the effects of asymmetric of the stenosis on the flow quantities.

Nonlinear Inelastic Mechanical Behavior Of Epoxy Resin Polymeric Materials

NASA Astrophysics Data System (ADS)

Yekani Fard, Masoud

Polymer and polymer matrix composites (PMCs) materials are being used extensively in different civil and mechanical engineering applications. The behavior of the epoxy resin polymers under different types of loading conditions has to be understood before the mechanical behavior of Polymer Matrix Composites (PMCs) can be accurately predicted. In many structural applications, PMC structures are subjected to large flexural loadings, examples include repair of structures against earthquake and engine fan cases. Therefore it is important to characterize and model the flexural mechanical behavior of epoxy resin materials. In this thesis, a comprehensive research effort was undertaken combining experiments and theoretical modeling to investigate the mechanical behavior of epoxy resins subject to different loading conditions. Epoxy resin E 863 was tested at different strain rates. Samples with dog-bone geometry were used in the tension tests. Small sized cubic, prismatic, and cylindrical samples were used in compression tests. Flexural tests were conducted on samples with different sizes and loading conditions. Strains were measured using the digital image correlation (DIC) technique, extensometers, strain gauges, and actuators. Effects of triaxiality state of stress were studied. Cubic, prismatic, and cylindrical compression samples undergo stress drop at yield, but it was found that only cubic samples experience strain hardening before failure. Characteristic points of tensile and compressive stress strain relation and load deflection curve in flexure were measured and their variations with strain rate studied. Two different stress strain models were used to investigate the effect of out-of-plane loading on the uniaxial stress strain response of the epoxy resin material. The first model is a strain softening with plastic flow for tension and compression. The influence of softening localization on material behavior was investigated using the DIC system. It was found that compression plastic flow has negligible influence on flexural behavior in epoxy resins, which are stronger in pre-peak and post-peak softening in compression than in tension. The second model was a piecewise-linear stress strain curve simplified in the post-peak response. Beams and plates with different boundary conditions were tested and analytically studied. The flexural over-strength factor for epoxy resin polymeric materials were also evaluated.

Unified Hall-Petch description of nano-grain nickel hardness, flow stress and strain rate sensitivity measurements

NASA Astrophysics Data System (ADS)

Armstrong, R. W.; Balasubramanian, N.

2017-08-01

It is shown that: (i) nano-grain nickel flow stress and hardness data at ambient temperature follow a Hall-Petch (H-P) relation over a wide range of grain size; and (ii) accompanying flow stress and strain rate sensitivity measurements follow an analogous H-P relationship for the reciprocal "activation volume", (1/v*) = (1/A*b) where A* is activation area. Higher temperature flow stress measurements show a greater than expected reduction both in the H-P kɛ and in v*. The results are connected with smaller nano-grain size (< ˜20 nm) measurements exhibiting grain size weakening behavior that extends to larger grain size when tested at very low imposed strain rates.

Influence of Thermocapillary Flow on Capillary Stability: Long Float-Zones in Low Gravity

NASA Technical Reports Server (NTRS)

Chen, Yi-Ju; Steen, Paul H.

1996-01-01

A model problem is posed to study the influence of flow on the interfacial stability of a nearly cylindrical liquid bridge for lengths near its circumference (the Plateau-Rayleigh limit). The flow is generated by a shear stress imposed on the deformable interface. The symmetry of the imposed shear stress mimics the thermocapillary stress induced on a float-zone by a ring heater (i.e. a full zone). Principal assumptions are (1) zero gravity, (2) creeping flow, and (3) that the imposed coupling at the free surface between flow and temperature fields is the only such coupling. A numerical solution, complemented by a bifurcation analysis, shows that bridges substantially longer than the Plateau-Rayleigh limit are possible. An interaction of the first two capillary instabilities through the stress-induced flow is responsible. Time-periodic standing waves are also predicted in certain parameter ranges. Motivation comes from extra-long float-zones observed in MEPHISTO space lab experiments (June 1994).

Determination of cohesive and normal stresses and simulation of fluidization using kinetic theory

NASA Astrophysics Data System (ADS)

Bezbaruah, R.

1991-08-01

The general objective of this study is focused on the solid stresses involved in gas-solid flow. These stresses are generally included in the momentum conservation equations, essentially for stability and to prevent particles from collapsing to unreasonably low values of gas volume fraction. The first half of this work undertakes the measurement of the stresses in various powders by direct means, while the second part uses a newly developed kinetic theory constitutive equation for stress to predict the flow and also the solid's viscosity in a CFB. The cohesive or tensile stress found to exist in some classes of powders is measured using a Cohetester, based on which a cohesive force model is derived, which is sensitive to the characteristic properties of the powder material. The normal stress is measured using a Consolidometer, and the powder solid's modulus is obtained as a function of the volume fraction. The solid's modulus is seen to vary with particle size and particle type, with the smaller size particles being more compressible. The simulation of flow in the CFB using Gidaspow's (1991) extension of Ding's (1990) kinetic theory model to dilute phase flow, predicts realistic values of solids' viscosity that are comparable to viscosities obtained experimentally by Miller (1991). However, to obtain a match between the two, the value of the restitution coefficient has to be close to unity. The flow behavior showed periodic oscillations of flow (turbulence) as seen in a real system.

Contribution of microreactor technology and flow chemistry to the development of green and sustainable synthesis

PubMed Central

Fanelli, Flavio; Parisi, Giovanna

2017-01-01

Microreactor technology and flow chemistry could play an important role in the development of green and sustainable synthetic processes. In this review, some recent relevant examples in the field of flash chemistry, catalysis, hazardous chemistry and continuous flow processing are described. Selected examples highlight the role that flow chemistry could play in the near future for a sustainable development. PMID:28405232

Fatigue response of perforated titanium for application in laminar flow control

NASA Technical Reports Server (NTRS)

Johnson, W. Steven; Miller, Jennifer L.; Newman, Jr., James

1996-01-01

The room temperature tensile and fatigue response of non-perforated and perforated titanium for laminar flow control application was investigated both experimentally and analytically. Results showed that multiple perforations did not affect the tensile response, but did reduce the fatigue life. A two dimensional finite element stress analysis was used to determine that the stress fields from adjacent perforations did not influence one another. The stress fields around the holes did not overlap one another, allowing the materials to be modeled as a plate with a center hole. Fatigue life was predicted using an equivalent MW flow size approach to relate the experimental results to microstructural features of the titanium. Predictions using flaw sizes ranging from 1 to 15 microns correlated within a factor of 2 with the experimental results by using a flow stress of 260 MPa. By using two different flow stresses in the crack closure model and correcting for plasticity, the experimental results were bounded by the predictions for high applied stresses. Further analysis of the complex geometry of the perforations and the local material chemistry is needed to further understand the fatigue behavior of the perforated titanium.

Towards a Simple Constitutive Model for Bread Dough

NASA Astrophysics Data System (ADS)

Tanner, Roger I.

2008-07-01

Wheat flour dough is an example of a soft solid material consisting of a gluten (rubbery) network with starch particles as a filler. The volume fraction of the starch filler is high-typically 60%. A computer-friendly constitutive model has been lacking for this type of material and here we report on progress towards finding such a model. The model must describe the response to small strains, simple shearing starting from rest, simple elongation, biaxial straining, recoil and various other transient flows. A viscoelastic Lodge-type model involving a damage function. which depends on strain from an initial reference state fits the given data well, and it is also able to predict the thickness at exit from dough sheeting, which has been a long-standing unsolved puzzle. The model also shows an apparent rate-dependent yield stress, although no explicit yield stress is built into the model. This behaviour agrees with the early (1934) observations of Schofield and Scott Blair on dough recoil after unloading.

Sinkhole development in Windsor-Detroit solution mines and the role of downward mass transfer in subsidence

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nieto, A.S.; Russell, D.G.

1984-01-01

The main portion of this paper deals with the development of three sinkholes of unexpected size and depth in the WindsorDetroit area. The roles of the Sylvania Sandstone - a unit of unique mechanical properties - and of the high in situ horizontal stresses are evaluated. It is proposed that the Sylvania fails under high horizontal loads, converts into sand, flows downward through cracks towards deeper solution-mine caverns, and creates a shallow void that generates the deep sinkholes. Linear-arch theory is used to evaluate subsidence-induced horizontal stress increments. It is concluded that sinkholes are likely to occur in other areasmore » where the Sylvania is close to the surface (less than 200 m) and active subsidence bowls have surface gradients of a few millimeters per meter. The last section contains a brief discussion of the role of downward mass transfer of slurries in surface subsidence with examples from the Midwest.« less

Simulations of blood flow through a stenosed carotid artery

NASA Astrophysics Data System (ADS)

Lundin, Staffan; Meder, Samuel; Metcalfe, Ralph

2000-11-01

The human carotid artery is often the site of the formation of atherosclerotic lesions that can lead to severe reduction of blood flow to the brain, frequently resulting in a stroke. There is strong evidence that hemodynamic variables such as the wall shear stress and its spatial and temporal derivatives play a role in fostering atherosclerosis. To investigate the potential of these effects, we have performed unsteady, three-dimensional numerical simulations of blood flow through the carotid bifurcation in the presence of stenoses of varying degrees and eccentricities. The simulations indicate that regions of low maximum and minimum shear stress correlate better with lesion prone sites than low average wall shear stress. As the degree of stenosis increases, it is found that the downstream flow changes drastically for stenoses greater than about 25Downstream eddies are generated during systole that create local shear stress peaks on the internal carotid artery wall, resulting in significant reduction in flow rates through the internal carotid artery. Large secondary flows develop, and there are also periods of flow reversal during the systolic/diastolic cycle.

Visual and psychological stress during computer work in healthy, young females-physiological responses.

PubMed

Mork, Randi; Falkenberg, Helle K; Fostervold, Knut Inge; Thorud, Hanne Mari S

2018-05-30

Among computer workers, visual complaints, and neck pain are highly prevalent. This study explores how occupational simulated stressors during computer work, like glare and psychosocial stress, affect physiological responses in young females with normal vision. The study was a within-subject laboratory experiment with a counterbalanced, repeated design. Forty-three females performed four 10-min computer-work sessions with different stress exposures: (1) minimal stress; (2) visual stress (direct glare); (3) psychological stress; and (4) combined visual and psychological stress. Muscle activity and muscle blood flow in trapezius, muscle blood flow in orbicularis oculi, heart rate, blood pressure, blink rate and postural angles were continuously recorded. Immediately after each computer-work session, fixation disparity was measured and a questionnaire regarding perceived workstation lighting and stress was completed. Exposure to direct glare resulted in increased trapezius muscle blood flow, increased blink rate, and forward bending of the head. Psychological stress induced a transient increase in trapezius muscle activity and a more forward-bent posture. Bending forward towards the computer screen was correlated with higher productivity (reading speed), indicating a concentration or stress response. Forward bent posture was also associated with changes in fixation disparity. Furthermore, during computer work per se, trapezius muscle activity and blood flow, orbicularis oculi muscle blood flow, and heart rate were increased compared to rest. Exposure to glare and psychological stress during computer work were shown to influence the trapezius muscle, posture, and blink rate in young, healthy females with normal binocular vision, but in different ways. Accordingly, both visual and psychological factors must be taken into account when optimizing computer workstations to reduce physiological responses that may cause excessive eyestrain and musculoskeletal load.

Calculation of turbulence-driven secondary motion in ducts with arbitrary cross section

NASA Technical Reports Server (NTRS)

Demuren, A. O.

1989-01-01

Calculation methods for turbulent duct flows are generalized for ducts with arbitrary cross-sections. The irregular physical geometry is transformed into a regular one in computational space, and the flow equations are solved with a finite-volume numerical procedure. The turbulent stresses are calculated with an algebraic stress model derived by simplifying model transport equations for the individual Reynolds stresses. Two variants of such a model are considered. These procedures enable the prediction of both the turbulence-driven secondary flow and the anisotropy of the Reynolds stresses, in contrast to some of the earlier calculation methods. Model predictions are compared to experimental data for developed flow in triangular duct, trapezoidal duct and a rod-bundle geometry. The correct trends are predicted, and the quantitative agreement is mostly fair. The simpler variant of the algebraic stress model procured better agreement with the measured data.

The stress heat-flow paradox and thermal results from Cajon Pass

USGS Publications Warehouse

Lachenbruch, A.H.; Sass, J.H.

1988-01-01

Conventional friction models predict a substantial thermal anomaly associated with active traces of strike-slip faults, but no such anomaly is observed from over 100 heat-flow determinations along 1000 km of the San Andreas fault. The Cajon Pass well is being drilled to bring deep heat-flow and stress data to bear on this paradox. Preliminary stress results from Cajon Pass and a new interpretation of regional data by Mark D. Zoback and colleagues suggests that the maximum compressive stress near the fault is almost normal to the trace, and hence the resolved shear stress is low and the fault, weak. The heat-flow data show large variability with depth, probably from three-dimensional structure, and an overall decrease from over 90 mW/m2 in the upper kilometer to less than 80 mW/m2 in the lower 300 m with no evidence of advective heat transfer. -from Authors

Development of an algebraic stress/two-layer model for calculating thrust chamber flow fields

NASA Technical Reports Server (NTRS)

Chen, C. P.; Shang, H. M.; Huang, J.

1993-01-01

Following the consensus of a workshop in Turbulence Modeling for Liquid Rocket Thrust Chambers, the current effort was undertaken to study the effects of second-order closure on the predictions of thermochemical flow fields. To reduce the instability and computational intensity of the full second-order Reynolds Stress Model, an Algebraic Stress Model (ASM) coupled with a two-layer near wall treatment was developed. Various test problems, including the compressible boundary layer with adiabatic and cooled walls, recirculating flows, swirling flows and the entire SSME nozzle flow were studied to assess the performance of the current model. Detailed calculations for the SSME exit wall flow around the nozzle manifold were executed. As to the overall flow predictions, the ASM removes another assumption for appropriate comparison with experimental data, to account for the non-isotropic turbulence effects.

North American water availability under stress and duress: building understanding from simulations, observations and data products

NASA Astrophysics Data System (ADS)

Maxwell, R. M.; Condon, L. E.; Atchley, A. L.; Hector, B.

2017-12-01

Quantifying the available freshwater for human use and ecological function depends on fluxes and stores that are hard to observe. Evapotranspiration (ET) is the largest terrestrial flux of water behind precipitation but is observed with low spatial density. Likewise, groundwater is the largest freshwater store, yet is equally uncertain. The ability to upscale observations of these variables is an additional complication; point measurements are made at scales orders of magnitude smaller than remote sensing data products. Integrated hydrologic models that simulate continental extents at fine spatial resolution are now becoming an additional tool to constrain fluxes and address interconnections. For example, recent work has shown connections between water table depth and transpiration partitioning, and demonstrated the ability to reconcile point observations and large-scale inferences. Here we explore the dynamics of large hydrologic systems experiencing change and stress across continental North America using integrated model simulations, observations and data products. Simulations of aquifer depletion due to pervasive groundwater pumping diagnose both stream depletion and changes in ET. Simulations of systematic increases in temperature are used to understand the relationship between snowpack dynamics, surface and groundwater flow, ET and a changing climate. Remotely sensed products including the GRACE estimates of total storage change are downscaled using model simulations to better understand human impacts to the hydrologic cycle. These example applications motivate a path forward to better use simulations to understand water availability.

Role of mixed boundaries on flow in open capillary channels with curved air-water interfaces.

PubMed

Zheng, Wenjuan; Wang, Lian-Ping; Or, Dani; Lazouskaya, Volha; Jin, Yan

2012-09-04

Flow in unsaturated porous media or in engineered microfluidic systems is dominated by capillary and viscous forces. Consequently, flow regimes may differ markedly from conventional flows, reflecting strong interfacial influences on small bodies of flowing liquids. In this work, we visualized liquid transport patterns in open capillary channels with a range of opening sizes from 0.6 to 5.0 mm using laser scanning confocal microscopy combined with fluorescent latex particles (1.0 μm) as tracers at a mean velocity of ∼0.50 mm s(-1). The observed velocity profiles indicate limited mobility at the air-water interface. The application of the Stokes equation with mixed boundary conditions (i.e., no slip on the channel walls and partial slip or shear stress at the air-water interface) clearly illustrates the increasing importance of interfacial shear stress with decreasing channel size. Interfacial shear stress emerges from the velocity gradient from the adjoining no-slip walls to the center where flow is trapped in a region in which capillary forces dominate. In addition, the increased contribution of capillary forces (relative to viscous forces) to flow on the microscale leads to increased interfacial curvature, which, together with interfacial shear stress, affects the velocity distribution and flow pattern (e.g., reverse flow in the contact line region). We found that partial slip, rather than the commonly used stress-free condition, provided a more accurate description of the boundary condition at the confined air-water interface, reflecting the key role that surface/interface effects play in controlling flow behavior on the nanoscale and microscale.

Dynamic Recrystallization Behavior of AISI 422 Stainless Steel During Hot Deformation Processes

NASA Astrophysics Data System (ADS)

Ahmadabadi, R. Mohammadi; Naderi, M.; Mohandesi, J. Aghazadeh; Cabrera, Jose Maria

2018-02-01

In this work, hot compression tests were performed to investigate the dynamic recrystallization (DRX) process of a martensitic stainless steel (AISI 422) at temperatures of 950, 1000, 1050, 1100 and 1150 °C and strain rates of 0.01, 0.1 and 1 s-1. The dependency of strain-hardening rate on flow stress was used to estimate the critical stress for the onset of DRX. Accordingly, the critical stress to peak stress ratio was calculated as 0.84. Moreover, the effect of true strain was examined by fitting stress values to an Arrhenius type constitutive equation, and then considering material constants as a function of strain by using a third-order polynomial equation. Finally, two constitutive models were used to investigate the competency of the strain-dependent constitutive equations to predict the flow stress curves of the studied steel. It was concluded that one model offers better precision on the flow stress values after the peak stress, while the other model gives more accurate results before the peak stress.

Response of hot element flush wall gauges in oscillating laminar flow

NASA Technical Reports Server (NTRS)

Giddings, T. A.; Cook, W. J.

1986-01-01

The time dependent response characteristics of flush-mounted hot element gauges used as instruments to measure wall shear stress in unsteady periodic air flows were investigated. The study was initiated because anomalous results were obtained from the gauges in oscillating turbulent flows for the phase relation of the wall shear stress variation, indicating possible gauge response problems. Flat plate laminar oscillating turbulent flows characterized by a mean free stream velocity with a superposed sinusoidal variation were performed. Laminar rather than turbulent flows were studied, because a numerical solution for the phase angle between the free stream velocity and the wall shear stress variation that is known to be correct can be obtained. The focus is on comparing the phase angle indicated by the hot element gauges with corresponding numerical prediction for the phase angle, since agreement would indicate that the hot element gauges faithfully follow the true wall shear stress variation.

Role of Reynolds Stress-Induced Poloidal Flow in Triggering the Transition to Improved Ohmic Confinement on the HT-6M Tokamak

NASA Astrophysics Data System (ADS)

Xu, Y. H.; Yu, C. X.; Luo, J. R.; Mao, J. S.; Liu, B. H.; Li, J. G.; Wan, B. N.; Wan, Y. X.

2000-04-01

Time and space resolved measurements of electrostatic Reynolds stress, radial electric field Er, and plasma rotations have been performed across the transition to improved Ohmic confinement in the Hefei Tokamak-6M (HT-6M). The first experimental evidence of the correlation between the enhanced Reynolds stress gradient and the poloidal flow acceleration in the edge plasma is presented. The results indicate that the turbulence-induced Reynolds stress might be the dominant mechanism to create the sheared poloidal flow and Er, which may further trigger the transition.

Role of reynolds stress-induced poloidal flow in triggering the transition to improved ohmic confinement on the HT-6M tokamak

PubMed

Xu; Yu; Luo; Mao; Liu; Li; Wan; Wan

2000-04-24

Time and space resolved measurements of electrostatic Reynolds stress, radial electric field E(r), and plasma rotations have been performed across the transition to improved Ohmic confinement in the Hefei Tokamak-6M (HT-6M). The first experimental evidence of the correlation between the enhanced Reynolds stress gradient and the poloidal flow acceleration in the edge plasma is presented. The results indicate that the turbulence-induced Reynolds stress might be the dominant mechanism to create the sheared poloidal flow and E(r), which may further trigger the transition.

L.D.V. measurements of unsteady flow fields in radial turbine

NASA Astrophysics Data System (ADS)

Tabakoff, W.; Pasin, M.

1992-07-01

Detailed measurements of an unsteady flow field within the inlet guide vanes (IGV) and the rotor of a radial inflow turbine were performed using a three component Laser Doppler Velocimeter (LDV) system together with a rotary encoder. The mean velocity, the flow angle and the turbulence contours for IGV passages are presented at four blade-to-blade planes for different rotor positions to give three dimensional, unsteady behavior of the IGV flow field. These results are compared with the measurements obtained in the same passage in the absence of the rotor. The flow field of the IGV passage was found to be affected by the presence of the rotor. The ratio of the tangential normal stresses to the radial normal stresses at the exit of the IGV was found to be more than doubled when compared to the case without the rotor. The rotor flow field measurements are presented as relative mean velocity and turbulence stress contours at various cross section planes throughout the rotor. The cross flow and turbulence stress levels were found to be influenced by the incidence angle. Transportation of the high turbulence fluid by the cross flow was observed downstream in the rotor blade passages.

Symmetry Breaking by Parallel Flow Shear

NASA Astrophysics Data System (ADS)

Li, Jiacong; Diamond, Patrick

2015-11-01

Plasma rotation is important in reducing turbulent transport, suppressing MHD instabilities, and is beneficial to confinement. Intrinsic rotation without an external momentum input is of interest for its plausible application on ITER. k∥ spectrum asymmetry is required for residual Reynolds stress that drives the intrinsic rotation. Parallel flows are reported in linear devices without magnetic shear. In CSDX, parallel flows are mostly peaked in the core [Thakur et al., 2014]; more robust flows and reversed profiles are seen in PANTA [Oldenburger, et al. 2012]. A novel mechanism for symmetry breaking in momentum transport is proposed. Magnetic shear or mean flow profile are not required. A seed parallel flow shear (PFS) sets the sign of residual stress by selecting certain modes to grow faster. The resulted spectrum imbalance leads to a nonzero residual stress, which further drives a parallel flow with ∇n as the free energy source, adding to the shear until saturated by diffusion. Balanced flow gradient is set by Π∥Res /χϕ . Residual stress is calculated for ITG turbulence and collisional drift wave turbulence where electron-ion and electron-neutral collisions are discussed and compared. Numerical simulation is proposed for testing the effect of PFS.

A model for wave propagation in a porous solid saturated by a three-phase fluid.

PubMed

Santos, Juan E; Savioli, Gabriela B

2016-02-01

This paper presents a model to describe the propagation of waves in a poroelastic medium saturated by a three-phase viscous, compressible fluid. Two capillary relations between the three fluid phases are included in the model by introducing Lagrange multipliers in the principle of virtual complementary work. This approach generalizes that of Biot for single-phase fluids and allows to determine the strain energy density, identify the generalized strains and stresses, and derive the constitutive relations of the system. The kinetic and dissipative energy density functions are obtained assuming that the relative flow within the pore space is of laminar type and obeys Darcy's law for three-phase flow in porous media. After deriving the equations of motion, a plane wave analysis predicts the existence of four compressional waves, denoted as type I, II, III, and IV waves, and one shear wave. Numerical examples showing the behavior of all waves as function of saturation and frequency are presented.

Single-scan rest/stress imaging: validation in a porcine model with 18F-Flurpiridaz.

PubMed

Guehl, Nicolas J; Normandin, Marc D; Wooten, Dustin W; Rozen, Guy; Sitek, Arkadiusk; Ruskin, Jeremy; Shoup, Timothy M; Ptaszek, Leon M; El Fakhri, Georges; Alpert, Nathaniel M

2017-08-01

18 F-labeled myocardial flow agents are becoming available for clinical application but the ∼2 hour half-life of 18 F complicates their clinical application for rest-stress measurements. The goal of this work is to evaluate in a pig model a single-scan method which provides quantitative rest-stress blood flow in less than 15 minutes. Single-scan rest-stress measurements were made using 18 F-Flurpiridaz. Nine scans were performed in healthy pigs and seven scans were performed in injured pigs. A two-injection, single-scan protocol was used in which an adenosine infusion was started 4 minutes after the first injection of 18 F-Flurpiridaz and followed either 3 or 6 minutes later by a second radiotracer injection. In two pigs, microsphere flow measurements were made at rest and during stress. Dynamic images were reoriented into the short axis view, and regions of interest (ROIs) for the 17 myocardial segments were defined in bull's eye fashion. PET data were fitted with MGH2, a kinetic model with time varying kinetic parameters, in which blood flow changes abruptly with the introduction of adenosine. Rest and stress myocardial blood flow (MBF) were estimated simultaneously. The first 12-14 minutes of rest-stress PET data were fitted in detail by the MGH2 model, yielding MBF measurement with a mean precision of 0.035 ml/min/cc. Mean myocardial blood flow across pigs was 0.61 ± 0.11 mL/min/cc at rest and 1.06 ± 0.19 mL/min/cc at stress in healthy pigs and 0.36 ± 0.20 mL/min/cc at rest and 0.62 ± 0.24 mL/min/cc at stress in the ischemic area. Good agreement was obtained with microsphere flow measurement (slope = 1.061 ± 0.017, intercept = 0.051 ± 0.017, mean difference 0.096 ± 0.18 ml/min/cc). Accurate rest and stress blood flow estimation can be obtained in less than 15 min of PET acquisition. The method is practical and easy to implement suggesting the possibility of clinical translation.

Prediction of Complex Aerodynamic Flows with Explicit Algebraic Stress Models

NASA Technical Reports Server (NTRS)

Abid, Ridha; Morrison, Joseph H.; Gatski, Thomas B.; Speziale, Charles G.

1996-01-01

An explicit algebraic stress equation, developed by Gatski and Speziale, is used in the framework of K-epsilon formulation to predict complex aerodynamic turbulent flows. The nonequilibrium effects are modeled through coefficients that depend nonlinearly on both rotational and irrotational strains. The proposed model was implemented in the ISAAC Navier-Stokes code. Comparisons with the experimental data are presented which clearly demonstrate that explicit algebraic stress models can predict the correct response to nonequilibrium flow.

Flow stress equations for type 304 stainless and AISI 1055 steels

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dadras, P.

A model for stress-strain behavior under hot working conditions has been proposed. Based on experimental data, equations for the dependence of flow stress on strain, strain rate, and temperature have been developed. Application to type 304 stainless steel and AISI 1055 steel has been demonstrated.

Flow behaviour and constitutive modelling of a ferritic stainless steel at elevated temperatures

NASA Astrophysics Data System (ADS)

Zhao, Jingwei; Jiang, Zhengyi; Zu, Guoqing; Du, Wei; Zhang, Xin; Jiang, Laizhu

2016-05-01

The flow behaviour of a ferritic stainless steel (FSS) was investigated by a Gleeble 3500 thermal-mechanical test simulator over the temperature range of 900-1100 °C and strain rate range of 1-50 s-1. Empirical and phenomenological constitutive models were established, and a comparative study was made on the predictability of them. The results indicate that the flow stress decreases with increasing the temperature and decreasing the strain rate. High strain rate may cause a drop in flow stress after a peak value due to the adiabatic heating. The Zener-Hollomon parameter depends linearly on the flow stress, and decreases with raising the temperature and reducing the strain rate. Significant deviations occur in the prediction of flow stress by the Johnson-Cook (JC) model, indicating that the JC model cannot accurately track the flow behaviour of the FSS during hot deformation. Both the multiple-linear and the Arrhenius-type models can track the flow behaviour very well under the whole hot working conditions, and have much higher accuracy in predicting the flow behaviour than that of the JC model. The multiple-linear model is recommended in the current work due to its simpler structure and less time needed for solving the equations relative to the Arrhenius-type model.

Toward a generalized equation for the Reynolds stress: Turbulence momentum balance in non-canonical flows

NASA Astrophysics Data System (ADS)

Lee, T.-W.

2017-11-01

Recently, we developed a theoretical basis for determination of the Reynolds stress in canonical flows. Writing momentum balance for a control volume moving at the local mean velocity, along with a differential transform ∂/∂x =C1 U∂/∂y , a turbulence momentum balance is discovered which includes the Reynolds stress as a function of root turbulence parameters: ∂(u'v')/∂y = -C1 U∂u'2/∂y +νm∂2urms'/∂y2 . Then, the Reynolds stress can simply be computed by integrating in the y-direction using the right-hand side (RHS). This is obviously a far simplification of complex modeling of the Reynolds stress, but contains the correct physics, as borne out by comparisons with experimental and DNS data in canonical flows in our earlier works (e.g. in APS 2016). The RHS contains only two parameters, U and u'. In this work, we seek extensions of this solution to non-canonical flows such as wakes, flow over a step, and mixing layers. Comparisons with experimental and DNS data will be presented.

Direct numerical simulation of curved turbulent channel flow

NASA Technical Reports Server (NTRS)

Moser, R. D.; Moin, P.

1984-01-01

Low Reynolds number, mildly curved, turbulent channel flow has been simulated numerically without subgrid scale models. A new spectral numerical method developed for this problem was used, and the computations were performed with 2 million degrees of freedom. A variety of statistical and structural information has been extracted from the computed flow fields. These include mean velocity, turbulence stresses, velocity skewness, and flatness factors, space time correlations and spectra, all the terms in the Reynolds stress balance equations, and contour and vector plots of instantaneous velocity fields. The effects of curvature on this flow were determined by comparing the concave and convex sides of the channel. The observed effects are consistent with experimental observations for mild curvature. The most significant difference in the turbulence statistics between the concave and convex sides was in the Reynolds shear stress. This was accompanied by significant differences in the terms of the Reynolds shear stress balance equations. In addition, it was found that stationary Taylor-Gortler vortices were present and that they had a significant effect on the flow by contributing to the mean Reynolds shear stress, and by affecting the underlying turbulence.

A probabilistic damage model of stress-induced permeability anisotropy during cataclastic flow

NASA Astrophysics Data System (ADS)

Zhu, Wenlu; MontéSi, Laurent G. J.; Wong, Teng-Fong

2007-10-01

A fundamental understanding of the effect of stress on permeability evolution is important for many fault mechanics and reservoir engineering problems. Recent laboratory measurements demonstrate that in the cataclastic flow regime, the stress-induced anisotropic reduction of permeability in porous rocks can be separated into 3 different stages. In the elastic regime (stage I), permeability and porosity reduction are solely controlled by the effective mean stress, with negligible permeability anisotropy. Stage II starts at the onset of shear-enhanced compaction, when a critical yield stress is attained. In stage II, the deviatoric stress exerts primary control over permeability and porosity evolution. The increase in deviatoric stress results in drastic permeability and porosity reduction and considerable permeability anisotropy. The transition from stage II to stage III takes place progressively during the development of pervasive cataclastic flow. In stage III, permeability and porosity reduction becomes gradual again, and permeability anisotropy diminishes. Microstructural observations on deformed samples using laser confocal microscopy reveal that stress-induced microcracking and pore collapse are the primary forms of damage during cataclastic flow. A probabilistic damage model is formulated to characterize the effects of stress on permeability and its anisotropy. In our model, the effects of both effective mean stress and differential stress on permeability evolution are calculated. By introducing stress sensitivity coefficients, we propose a first-order description of the dependence of permeability evolution on different loading paths. Built upon the micromechanisms of deformation in porous rocks, this unified model provides new insight into the coupling of stress and permeability.

Impact of Stress on Anomalous Transport in Fractured Rock

NASA Astrophysics Data System (ADS)

Kang, P. K.; Lei, Q.; Lee, S.; Dentz, M.; Juanes, R.

2016-12-01

Fluid flow and transport in fractured rock controls many natural and engineered processes in the subsurface. However, characterizing flow and transport through fractured media is challenging due to the large heterogeneity of fractured rock properties. In addition to these "static" challenges, geologic fractures are always under significant overburden stress, and changes in the stress state can lead to changes in the fracture's ability to conduct fluids. While confining stress has been shown to impact fluid flow through fractures in a fundamental way, the impact of confining stress on transport through fractured rock remains largely unexplored. The link between anomalous (non-Fickian) transport and confining stress has been shown only recently, at the level of a single rough fracture [1]. Here, we investigate the impact of confining stress on flow and transport through discrete fracture networks. We model geomechanical effects in 2D fractured rock by means of a finite-discrete element method (FEMDEM), which can capture the deformation of matrix blocks, reactivation and propagation of cracks. We implement a joint constitutive model within the FEMDEM framework to simulate the effect of fracture roughness. We apply the model to a fracture network extracted from the geological map of an actual outcrop to obtain the aperture field at different stress conditions (Figure 1). We then simulate fluid flow and particle transport through the stressed fracture networks. We observe that anomalous transport emerges in response to confining stress on the fracture networks, and show that this anomalous behavior can be linked to the stress state of the rock. Finally, we develop an effective transport model that captures the anomalous transport through stressed fractures. Our results point to a heretofore unrecognized link between geomechanics and anomalous transport in discrete fractured networks. [1] P. K. Kang, S. Brown, and R. Juanes, Emergence of anomalous transport in stressed rough fractures. Earth and Planetary Science Letters, to appear (2016). Figure (a) Map of maximum principal stress with a vertical normal compressive stress of 3 MPa at top and bottom boundaries, and 1MPa at left and right boundaries. (b) Normal compressive stress of 15 MPa at top and bottom boundaries, and 5MPa at left and right boundaries.

Influence of Stress State, Stress Orientation, and Rock Properties on the Development of Deformation-Band 'Ladder' Arrays in Porous Sandstone

NASA Astrophysics Data System (ADS)

Schultz, R. A.; Soliva, R.; Fossen, H.

2013-12-01

Deformation bands in porous rocks tend to develop into spatially organized arrays that display a variety of lengths and thicknesses, and their geometries and arrangements are of interest with respect to fluid flow in reservoirs. Field examples of deformation band arrays in layered clastic sequences suggest that the development of classic deformation band arrays, such as ladders and conjugate sets, and the secondary formation of through-going faults appear to be related to the physical properties of the host rock, the orientation of stratigraphic layers relative to the far-field stress state, and the evolution of the local stress state within the developing array. We have identified several field examples that demonstrate changes in band properties, such as type and orientation, as a function of one or more of these three main factors. Normal-sense deformation-band arrays such as those near the San Rafael Swell (Utah) develop three-dimensional ladder-style arrays at a high angle to the maximum compression direction; these cataclastic shear bands form at acute angles to the maximum compression not very different from that of the optimum frictional sliding plane, thus facilitating the eventual nucleation of a through-going fault. At Orange quarry (France), geometrically conjugate sets of reverse-sense compactional shear bands form with angles to the maximum compression direction that inhibit fault nucleation within them; the bands in this case also form at steep enough angles to bedding that stratigraphic heterogeneities within the deforming formation were apparently not important. Two exposures of thrust-sense ladders at Buckskin Gulch (Utah) demonstrate the importance of host-rock properties, bedding-plane involvement, and local stress perturbations on band-array growth. In one ladder, thrust-sense shear deformation bands nucleated along suitably oriented bedding planes, creating overprinting sets of compaction bands that can be attributed to layer properties and local stress changes near the shear-band tips. Two other ladder exposures preserve compaction bands having nearly perpendicular orientations relative the bounding shear bands that define contractional stepovers that also nucleated on bedding planes. These cases suggest that local stress changes within a deformation-band stepover may lead to either rotation of bands or changes in band type relative to bands formed outside the stepover. The development of the common geometries of deformation band arrays, such as ladders, and the deformation paths to faulting thus depend on a combination of stress state, stress orientation, and rock properties.

Fluorescence-based detection and quantification of features of cellular senescence.

PubMed

Cho, Sohee; Hwang, Eun Seong

2011-01-01

Cellular senescence is a spontaneous organismal defense mechanism against tumor progression which is raised upon the activation of oncoproteins or other cellular environmental stresses that must be circumvented for tumorigenesis to occur. It involves growth-arrest state of normal cells after a number of active divisions. There are multiple experimental routes that can drive cells into a state of senescence. Normal somatic cells and cancer cells enter a state of senescence upon overexpression of oncogenic Ras or Raf protein or by imposing certain kinds of stress such as cellular tumor suppressor function. Both flow cytometry and confocal imaging analysis techniques are very useful in quantitative analysis of cellular senescence phenomenon. They allow quantitative estimates of multiple different phenotypes expressed in multiple cell populations simultaneously. Here we review the various types of fluorescence methodologies including confocal imaging and flow cytometry that are frequently utilized to study a variety of senescence. First, we discuss key cell biological changes occurring during senescence and review the current understanding on the mechanisms of these changes with the goal of improving existing protocols and further developing new ones. Next, we list specific senescence phenotypes associated with each cellular trait along with the principles of their assay methods and the significance of the assay outcomes. We conclude by selecting appropriate references that demonstrate a typical example of each method. Copyright © 2011 Elsevier Inc. All rights reserved.

MHD Flow and Heat Transfer of a Generalized Burgers’ Fluid due to a Periodic Oscillating and Periodic Heating Plate

NASA Astrophysics Data System (ADS)

Bai, Yu; Jiang, Yue-Hua; Zhang, Yan; Zhao, Hao-Jie

2017-10-01

This paper investigates the MHD flow and heat transfer of the incompressible generalized Burgers’ fluid due to a periodic oscillating plate with the effects of the second order slip and periodic heating plate. The momentum equation is formulated with multi-term fractional derivatives, and by means of viscous dissipation, the fractional derivative is considered in the energy equation. A finite difference scheme is established based on the G1-algorithm, whose convergence is confirmed by the comparison with the analytical solution in an example. Meanwhile the numerical solutions of velocity, temperature and shear stress are obtained. The effects of involved parameters on velocity and temperature fields are presented graphically and analyzed in detail. Increasing the fractional derivative parameter α, the velocity and temperature have a decreasing trend, while the influences of fractional derivative parameter β on the velocity and temperature behave conversely. Increasing the absolute value of the first order slip parameter and the second order slip parameter both cause a decrease of velocity. Furthermore, with the decreasing of the magnetic parameter, the shear stress decreases. Supported by the National Natural Science Foundations of China under Grant Nos. 21576023, 51406008, the National Key Research Program of China under Grant Nos. 2016YFC0700601, 2016YFC0700603 and the BUCEA Post Graduate Innovation Project (PG2017032)

Shear stress increases nitric oxide production in thick ascending limbs

PubMed Central

Cabral, Pablo D.; Hong, Nancy J.

2010-01-01

We showed that luminal flow stimulates nitric oxide (NO) production in thick ascending limbs. Ion delivery, stretch, pressure, and shear stress all increase when flow is enhanced. We hypothesized that shear stress stimulates NO in thick ascending limbs, whereas stretch, pressure, and ion delivery do not. We measured NO in isolated, perfused rat thick ascending limbs using the NO-sensitive dye DAF FM-DA. NO production rose from 21 ± 7 to 58 ± 12 AU/min (P < 0.02; n = 7) when we increased luminal flow from 0 to 20 nl/min, but dropped to 16 ± 8 AU/min (P < 0.02; n = 7) 10 min after flow was stopped. Flow did not increase NO in tubules from mice lacking NO synthase 3 (NOS 3). Flow stimulated NO production by the same extent in tubules perfused with ion-free solution and physiological saline (20 ± 7 vs. 24 ± 6 AU/min; n = 7). Increasing stretch while reducing shear stress and pressure lowered NO generation from 42 ± 9 to 17 ± 6 AU/min (P < 0.03; n = 6). In the absence of shear stress, increasing pressure and stretch had no effect on NO production (2 ± 8 vs. 8 ± 8 AU/min; n = 6). Similar results were obtained in the presence of tempol (100 μmol/l), a O2− scavenger. Primary cultures of thick ascending limb cells subjected to shear stresses of 0.02 and 0.55 dyne/cm2 produced NO at rates of 55 ± 10 and 315 ± 93 AU/s, respectively (P < 0.002; n = 7). Pretreatment with the NOS inhibitor l-NAME (5 mmol/l) blocked the shear stress-induced increase in NO production. We concluded that shear stress rather than pressure, stretch, or ion delivery mediates flow-induced stimulation of NO by NOS 3 in thick ascending limbs. PMID:20719980

Seeking simplicity for the understanding of multiphase flows

NASA Astrophysics Data System (ADS)

Stone, Howard A.

2017-10-01

Fluid mechanics is a discipline with rich phenomena, with motions occurring over an enormous range of length scales, and spanning a wide range of laminar and turbulent flows, instabilities, and applications in industry, nature, biology, and medicine. The subfield of complex fluids typically refers to those flows where the complexity is introduced, for example, by the presence of suspended particles, multiple phases, soft boundaries, and electrokinetic effects; several distinct multiphase flows of Newtonian fluids make up the examples in this article. Interfaces play a significant role and modify the flow with feedback that further changes the shapes of the interfaces. I will provide examples of our work highlighting (i) new features of classical instabilities triggered by changes in geometry, (ii) multiphase flows relevant to the design of liquid-infused substrates exhibiting effective slip while retaining the trapped liquid, and (iii) unexpected dynamics in flow at a T-junction. The interplay of experiments and mathematical models and/or simulations is critical to the new understanding developed.

Theories of binary fluid mixtures: from phase-separation kinetics to active emulsions

NASA Astrophysics Data System (ADS)

Cates, Michael E.; Tjhung, Elsen

2018-02-01

Binary fluid mixtures are examples of complex fluids whose microstructure and flow are strongly coupled. For pairs of simple fluids, the microstructure consists of droplets or bicontinuous demixed domains and the physics is controlled by the interfaces between these domains. At continuum level, the structure is defined by a composition field whose gradients which are steep near interfaces drive its diffusive current. These gradients also cause thermodynamic stresses which can drive fluid flow. Fluid flow in turn advects the composition field, while thermal noise creates additional random fluxes that allow the system to explore its configuration space and move towards the Boltzmann distribution. This article introduces continuum models of binary fluids, first covering some well-studied areas such as the thermodynamics and kinetics of phase separation, and emulsion stability. We then address cases where one of the fluid components has anisotropic structure at mesoscopic scales creating nematic (or polar) liquid-crystalline order; this can be described through an additional tensor (or vector) order parameter field. We conclude by outlining a thriving area of current research, namely active emulsions, in which one of the binary components consists of living or synthetic material that is continuously converting chemical energy into mechanical work.

Augment clinical measurement using a constraint-based esophageal model

NASA Astrophysics Data System (ADS)

Kou, Wenjun; Acharya, Shashank; Kahrilas, Peter; Patankar, Neelesh; Pandolfino, John

2017-11-01

Quantifying the mechanical properties of the esophageal wall is crucial to understanding impairments of trans-esophageal flow characteristic of several esophageal diseases. However, these data are unavailable owing to technological limitations of current clinical diagnostic instruments that instead display esophageal luminal cross sectional area based on intraluminal impedance change. In this work, we developed an esophageal model to predict bolus flow and the wall property based on clinical measurements. The model used the constraint-based immersed-boundary method developed previously by our group. Specifically, we first approximate the time-dependent wall geometry based on impedance planimetry data on luminal cross sectional area. We then fed these along with pressure data into the model and computed wall tension based on simulated pressure and flow fields, and the material property based on the strain-stress relationship. As examples, we applied this model to augment FLIP (Functional Luminal Imaging Probe) measurements in three clinical cases: a normal subject, achalasia, and eosinophilic esophagitis (EoE). Our findings suggest that the wall stiffness was greatest in the EoE case, followed by the achalasia case, and then the normal. This is supported by NIH Grant R01 DK56033 and R01 DK079902.

Interaction between the Stress Phase Angle (SPA) and the Oscillatory Shear Index (OSI) Affects Endothelial Cell Gene Expression.

PubMed

Amaya, Ronny; Cancel, Limary M; Tarbell, John M

2016-01-01

Hemodynamic forces play an important role in the non-uniform distribution of atherosclerotic lesions. Endothelial cells are exposed simultaneously to fluid wall shear stress (WSS) and solid circumferential stress (CS). Due to variations in impedance (global factors) and geometric complexities (local factors) in the arterial circulation a time lag arises between these two forces that can be characterized by the temporal phase angle between CS and WSS (stress phase angle-SPA). Asynchronous flows (SPA close to -180°) that are most prominent in coronary arteries have been associated with localization of atherosclerosis. Reversing oscillatory flows characterized by an oscillatory shear index (OSI) that is great than zero are also associated with atherosclerosis localization. In this study we examined the relationship between asynchronous flows and reversing flows in altering the expression of 37 genes relevant to atherosclerosis development. In the case of reversing oscillatory flow, we observed that the asynchronous condition upregulated 8 genes compared to synchronous hemodynamics, most of them proatherogenic. Upregulation of the pro-inflammatory transcription factor NFκB p65 was confirmed by western blot, and nuclear translocation of NFκB p65 was confirmed by immunofluorescence staining. A comparative study between non-reversing flow and reversing flow found that in the case of synchronous hemodynamics, reversing flow altered the expression of 11 genes, while in the case of asynchronous hemodynamics, reversing flow altered the expression of 17 genes. Reversing flow significantly upregulated protein expression of NFκB p65 for both synchronous and asynchronous conditions. Nuclear translocation of NFκB p65 was confirmed for synchronous and asynchronous conditions in the presence of flow reversal. These data suggest that asynchronous hemodynamics and reversing flow can elicit proatherogenic responses in endothelial cells compared to synchronous hemodynamics without shear stress reversal, indicating that SPA as well as reversal flow (OSI) are important parameters characterizing arterial susceptibility to disease.

Interaction between the Stress Phase Angle (SPA) and the Oscillatory Shear Index (OSI) Affects Endothelial Cell Gene Expression

PubMed Central

Amaya, Ronny; Cancel, Limary M.; Tarbell, John M.

2016-01-01

Hemodynamic forces play an important role in the non-uniform distribution of atherosclerotic lesions. Endothelial cells are exposed simultaneously to fluid wall shear stress (WSS) and solid circumferential stress (CS). Due to variations in impedance (global factors) and geometric complexities (local factors) in the arterial circulation a time lag arises between these two forces that can be characterized by the temporal phase angle between CS and WSS (stress phase angle–SPA). Asynchronous flows (SPA close to -180°) that are most prominent in coronary arteries have been associated with localization of atherosclerosis. Reversing oscillatory flows characterized by an oscillatory shear index (OSI) that is great than zero are also associated with atherosclerosis localization. In this study we examined the relationship between asynchronous flows and reversing flows in altering the expression of 37 genes relevant to atherosclerosis development. In the case of reversing oscillatory flow, we observed that the asynchronous condition upregulated 8 genes compared to synchronous hemodynamics, most of them proatherogenic. Upregulation of the pro-inflammatory transcription factor NFκB p65 was confirmed by western blot, and nuclear translocation of NFκB p65 was confirmed by immunofluorescence staining. A comparative study between non-reversing flow and reversing flow found that in the case of synchronous hemodynamics, reversing flow altered the expression of 11 genes, while in the case of asynchronous hemodynamics, reversing flow altered the expression of 17 genes. Reversing flow significantly upregulated protein expression of NFκB p65 for both synchronous and asynchronous conditions. Nuclear translocation of NFκB p65 was confirmed for synchronous and asynchronous conditions in the presence of flow reversal. These data suggest that asynchronous hemodynamics and reversing flow can elicit proatherogenic responses in endothelial cells compared to synchronous hemodynamics without shear stress reversal, indicating that SPA as well as reversal flow (OSI) are important parameters characterizing arterial susceptibility to disease. PMID:27846267

Effectiveness of Myocardial Contrast Echocardiography Quantitative Analysis during Adenosine Stress versus Visual Analysis before Percutaneous Therapy in Acute Coronary Pain: A Coronary Artery TIMI Grading Comparing Study

PubMed Central

Yang, Lixia; Mu, Yuming; Quaglia, Luiz Augusto; Tang, Qi; Guan, Lina; Wang, Chunmei; Shih, Ming Chi

2012-01-01

The study aim was to compare two different stress echocardiography interpretation techniques based on the correlation with thrombosis in myocardial infarction (TIMI ) flow grading from acute coronary syndrome (ACS) patients. Forty-one patients with suspected ACS were studied before diagnostic coronary angiography with myocardial contrast echocardiography (MCE) at rest and at stress. The correlation of visual interpretation of MCE and TIMI flow grade was significant. The quantitative analysis (myocardial perfusion parameters: A, β, and A × β) and TIMI flow grade were significant. MCE visual interpretation and TIMI flow grade had a high degree of agreement, on diagnosing myocardial perfusion abnormality. If one considers TIMI flow grade <3 as abnormal, MCE visual interpretation at rest had 73.1% accuracy with 58.2% sensitivity and 84.2% specificity and at stress had 80.4% accuracy with 76.6% sensitivity and 83.3% specificity. The MCE quantitative analysis has better accuracy with 100% of agreement with different level of TIMI flow grading. MCE quantitative analysis at stress has showed a direct correlation with TIMI flow grade, more significant than the visual interpretation technique. Further studies could measure the clinical relevance of this more objective approach to managing acute coronary syndrome patient before percutaneous coronary intervention (PCI). PMID:22778555

In situ monitoring of localized shear stress and fluid flow within developing tissue constructs by Doppler optical coherence tomography

NASA Astrophysics Data System (ADS)

Jia, Yali; Bagnaninchi, Pierre O.; Wang, Ruikang K.

2008-02-01

Mechanical stimuli can be introduced to three dimensional (3D) cell cultures by use of perfusion bioreactor. Especially in musculoskeletal tissues, shear stress caused by fluid flow generally increase extra-cellular matrix (ECM) production and cell proliferation. The relationship between the shear stress and the tissue development in situ is complicated because of the non-uniform pore distribution within the cell-seeded scaffold. In this study, we firstly demonstrated that Doppler optical coherence tomography (DOCT) is capable of monitoring localized fluid flow and shear stress in the complex porous scaffold by examining their variation trends at perfusion rate of 5, 8, 10 and 12 ml/hr. Then, we developed the 3D porous cellular constructs, cell-seeded chitosan scaffolds monitored during several days by DOCT. The fiber based fourier domain DOCT employed a 1300 nm superluminescent diode with a bandwidth of 52 nm and a xyz resolution of 20×20×15 μm in free space. This setup allowed us not only to assess the cell growth and ECM deposition by observing their different scattering behaviors but also to further investigate how the cell attachment and ECM production has the effect on the flow shear stress and the relationship between flow rate and shear stress in the developing tissue construct. The possibility to monitor continuously the constructs under perfusion will easily indicate the effect of flow rate or shear stress on the cell viability and cell proliferation, and then discriminate the perfusion parameters affecting the pre-tissue formation rate growth.

Active Control of Combustion Instability in a Ramjet Using Large-Eddy Simulations

DTIC Science & Technology

1992-09-01

model is also used to determine the turbulent subgrid fluxes appearing in the momentum equations. Thus, the subgrid stresses in the momentum transport...flows and in flows with complex geometries. To include the effect of walls, an additional correction has been used to ensure that the subgrid stress ...subgrid stress Ty varies as y+3 near the wall. A major issue for LES of complex flows is whether the primary assumption that the subgrid scales are

Stress and vascular responses: atheroprotective effect of laminar fluid shear stress in endothelial cells: possible role of mitogen-activated protein kinases.

PubMed

Yoshizumi, Masanori; Abe, Jun-Ichi; Tsuchiya, Koichiro; Berk, Bradford C; Tamaki, Toshiaki

2003-03-01

Atherosclerosis preferentially occurs in areas of turbulent blood flow and low fluid shear stress, whereas laminar blood flow and high shear stress are atheroprotective. Inflammatory cytokines, such as tumor necrosis factor-alpha (TNF-alpha), stimulate expression of endothelial cell (EC) genes that may promote atherosclerosis. Recent findings suggest a steady laminar blood flow decreases EC apoptosis and inhibits TNF-mediated EC activation. EC apoptosis or activation is suggested to be involved in plaque erosion, which may lead to platelet aggregation. TNF-alpha regulates gene expression in ECs, in part, by stimulating mitogen-activated protein (MAP) kinases, which phosphorylate transcription factors. We hypothesized that steady laminar flow inhibits cytokine-mediated activation of MAP kinases in ECs. To test this hypothesis, we determined the effects of steady laminar flow (shear stress = 12 dynes/cm(2)) on TNF-alpha-stimulated activity of three MAP kinases in human umbilical vein ECs (HUVEC): extracellular signal-regulated kinase (ERK1/2), c-Jun N-terminal kinase (JNK), and p38. TNF-alpha activated ERK1/2, JNK, and p38 maximally at 15 min in HUVEC. Pre-exposing HUVEC for 10 min to flow inhibited TNF-alpha activation of JNK, but showed no significant effect on ERK1/2 or p38 activation. Incubation of HUVEC with PD98059, a specific ERK1/2 inhibitor, blocked the flow-mediated inhibition of TNF activation of JNK. Transfection studies with dominant-negative constructs of the protein kinase MEK5 suggested an important role for big mitogen-activated protein kinase 1 (BMK1) in flow-mediated regulation of EC activation by TNF-alpha. Understanding the mechanisms by which steady laminar flow regulates JNK activation by cytokines may provide insight into the atheroprotective mechanisms induced by laminar blood flow.

Modeling of Wall-Bounded Complex Flows and Free Shear Flows

NASA Technical Reports Server (NTRS)

Shih, Tsan-Hsing; Zhu, Jiang; Lumley, John L.

1994-01-01

Various wall-bounded flows with complex geometries and free shear flows have been studied with a newly developed realizable Reynolds stress algebraic equation model. The model development is based on the invariant theory in continuum mechanics. This theory enables us to formulate a general constitutive relation for the Reynolds stresses. Pope was the first to introduce this kind of constitutive relation to turbulence modeling. In our study, realizability is imposed on the truncated constitutive relation to determine the coefficients so that, unlike the standard k-E eddy viscosity model, the present model will not produce negative normal stresses in any situations of rapid distortion. The calculations based on the present model have shown an encouraging success in modeling complex turbulent flows.

Worksite Stress Management Interventions.

ERIC Educational Resources Information Center

Ivancevich, John M.; And Others

1990-01-01

Presents a framework used for viewing stress and organizational stress interventions. Reviews the stress management intervention literature in the context of this framework. Provides examples of corporations committed to stress management programs. Identifies future needs appropriate for organizational psychologists to address. (Author/JS)

Plastic Stress-strain Relations for 75S-T6 Aluminum Alloy Subjected to Biaxial Tensile Stresses

NASA Technical Reports Server (NTRS)

Marin, Joseph; Ulrich, B H; Hughes, W P

1951-01-01

In this investigation, the material tested was a 75S-T6 aluminum alloy and the stresses were essentially biaxial and tensile. The biaxial tensile stresses were produced in a specially designed testing machine by subjecting a thin-walled tubular specimen to axial tension and internal pressure. Plastic stress-strain relations for various biaxial stress conditions were obtained using a clip-type SR-4 strain gage. Three types of tests were made: Constant-stress-ratio tests, variable-stress-ratio tests, and special tests. The constant-stress-ratio test results gave control data and showed the influence of biaxial stresses on the yield, fracture, and ultimate strength of the material. By means of the variable-stress-ratio tests, it is possible to determine whether there is any significant difference between the flow and deformation type of theory. Finally, special tests were conducted to check specific assumptions made in the theories of plastic flow. The constant-stress-ratio tests show that the deformation theory based on the octahedral, effective; or significant stress-strain relations is in approximate agreement with the test results. The variable-stress-ratio tests show that both the deformation and flow theory are in equally good agreement with the test results.

Tensile stress-strain and work hardening behaviour of P9 steel for wrapper application in sodium cooled fast reactors

NASA Astrophysics Data System (ADS)

Christopher, J.; Choudhary, B. K.; Isaac Samuel, E.; Mathew, M. D.; Jayakumar, T.

2012-01-01

Tensile flow behaviour of P9 steel with different silicon content has been examined in the framework of Hollomon, Ludwik, Swift, Ludwigson and Voce relationships for a wide temperature range (300-873 K) at a strain rate of 1.3 × 10 -3 s -1. Ludwigson equation described true stress ( σ)-true plastic strain ( ɛ) data most accurately in the range 300-723 K. At high temperatures (773-873 K), Ludwigson equation reduces to Hollomon equation. The variations of instantaneous work hardening rate ( θ = dσ/ dɛ) and θσ with stress indicated two-stage work hardening behaviour. True stress-true plastic strain, flow parameters, θ vs. σ and θσ vs. σ with respect to temperature exhibited three distinct temperature regimes and displayed anomalous behaviour due to dynamic strain ageing at intermediate temperatures. Rapid decrease in flow stress and flow parameters, and rapid shift in θ- σ and θσ- σ towards lower stresses with increase in temperature indicated dominance of dynamic recovery at high temperatures.

Experimental Study of a Three-Dimensional Shear-Driven Turbulent Boundary Layer with Streamwise Adverse Pressure Gradient

NASA Technical Reports Server (NTRS)

Driver, David M.; Johnston, James P.

1990-01-01

The effects of a strong adverse pressure gradient on a three-dimensional turbulent boundary layer are studied in an axisymmetric spinning cylinder geometry. Velocity measurements made with a three-component laser Doppler velocimeter include all three mean flow components, all six Reynolds stress components, and all ten triple-product correlations. Reynolds stress diminishes as the flow becomes three-dimensional. Lower levels of shear stress were seen to persist under adverse pressure gradient conditions. This low level of stress was seen to roughly correlate with the magnitude of cross-flow (relative to free stream flow) for this experiment as well as most of the other experiments in the literature. Variations in pressure gradient do not appear to alter this correlation. For this reason, it is hypothesized that a three-dimensional boundary layer is more prone to separate than a two-dimensional boundary layer, although it could not be directly shown here. None of the computations performed with either a Prandtl mixing length, k-epsilon, or a Launder-Reece-Rodi full Reynolds-stress model were able to predict the reduction in Reynolds stress.

Fluid structure interaction dynamic analysis of a mixed-flow waterjet pump

NASA Astrophysics Data System (ADS)

Pan, X. W.; Y Pan, Z.; Huang, D.; Shen, Z. H.

2013-12-01

In order to avoid resonance of a mixed-flow waterjet pump at run time and calculate the stress and deformation of the pump rotor in the flow field, a one-way fluid structure interaction method was applied to simulate the pump rotor using ANSYS CFX and ANSYS Workbench software. The natural frequencies and mode shapes of the pump rotor in the air and in the flow field were analyzed, and the stress and deformation of the impeller were obtained at different flow rates. The obtained numerical results indicated that the mode shapes were similar both in the air and in the flow field, but the pump rotor's natural frequency in the flow field was slightly smaller than that in the air; the difference of the pump rotor's natural frequency varied lightly at different flow rates, and all frequencies at different flow rates were higher than the safe frequency, the pump rotor under the effect of prestress rate did not occur resonance; The maximum stress was on the blade near the hub and the maximum deformation on the blade tip at different flow rates.

Analysis of temporal shear stress gradients during the onset phase of flow over a backward-facing step.

PubMed

Haidekker, M A; White, C R; Frangos, J A

2001-10-01

Endothelial cells in blood vessels are exposed to bloodflow and thus fluid shear stress. In arterial bifurcations and stenoses, disturbed flow causes zones of recirculation and stagnation, which are associated with both spatial and temporal gradients of shear stress. Such gradients have been linked to the generation of atherosclerotic plaques. For in-vitro studies of endothelial cell responses, the sudden-expansion flow chamber has been widely used and described. A two-dimensional numerical simulation of the onset phase of flow through the chamber was performed. The wall shear stress action on the bottom plate was computed as a function of time and distance from the sudden expansion. The results showed that depending on the time for the flow to be established, significant temporal gradients occurred close to the second stagnation point of flow. Slowly ramping the flow over 15 s instead of 200 ms reduces the temporal gradients by a factor of 300, while spatial gradients are reduced by 23 percent. Thus, the effects of spatial and temporal gradients can be observed separately. In experiments on endothelial cells, disturbed flow stimulated cell proliferation only when flow onset was sudden. The spatial patterns of proliferation rate match the exposure to temporal gradients. This study provides information on the dynamics of spatial and temporal gradients to which the cells are exposed in a sudden-expansion flow chamber and relates them to changes in the onset phase of flow.

Comparison of in vitro flows past a mechanical heart valve in anatomical and axisymmetric aorta models

NASA Astrophysics Data System (ADS)

Haya, Laura; Tavoularis, Stavros

2017-06-01

Flow characteristics past a bileaflet mechanical heart valve were measured under physiological flow conditions in a straight tube with an axisymmetric expansion, similar to vessels used in previous studies, and in an anatomical model of the aorta. We found that anatomical features, including the three-lobed sinus and the aorta's curvature affected significantly the flow characteristics. The turbulent and viscous stresses were presented and discussed as indicators for potential blood damage and thrombosis. Both types of stresses, averaged over the two axial measurement planes, were significantly lower in the anatomical model than in the axisymmetric one. This difference was attributed to the lower height-to-width ratio and more gradual contraction of the anatomical aortic sinus. The curvature of the aorta caused asymmetries in the velocity and stress distributions during forward flow. Secondary flows resulting from the aorta's curvature are thought to have redistributed the fluid stresses transversely, resulting in a more homogeneous stress distribution in the anatomical aortic root than in the axisymmetric root. The results of this study demonstrate the importance of modelling accurately the aortic geometry in experimental and computational studies of prosthetic devices. Moreover, our findings suggest that grafts used for aortic root replacement should approximate as closely as possible the shape of the natural sinuses.

SedFoam-2.0: a 3-D two-phase flow numerical model for sediment transport

NASA Astrophysics Data System (ADS)

Chauchat, Julien; Cheng, Zhen; Nagel, Tim; Bonamy, Cyrille; Hsu, Tian-Jian

2017-11-01

In this paper, a three-dimensional two-phase flow solver, SedFoam-2.0, is presented for sediment transport applications. The solver is extended from twoPhaseEulerFoam available in the 2.1.0 release of the open-source CFD (computational fluid dynamics) toolbox OpenFOAM. In this approach the sediment phase is modeled as a continuum, and constitutive laws have to be prescribed for the sediment stresses. In the proposed solver, two different intergranular stress models are implemented: the kinetic theory of granular flows and the dense granular flow rheology μ(I). For the fluid stress, laminar or turbulent flow regimes can be simulated and three different turbulence models are available for sediment transport: a simple mixing length model (one-dimensional configuration only), a k - ɛ, and a k - ω model. The numerical implementation is demonstrated on four test cases: sedimentation of suspended particles, laminar bed load, sheet flow, and scour at an apron. These test cases illustrate the capabilities of SedFoam-2.0 to deal with complex turbulent sediment transport problems with different combinations of intergranular stress and turbulence models.

Stress modeling in colloidal dispersions undergoing non-viscometric flows

NASA Astrophysics Data System (ADS)

Dolata, Benjamin; Zia, Roseanna

2017-11-01

We present a theoretical study of the stress tensor for a colloidal dispersion undergoing non-viscometric flow. In such flows, the non-homogeneous suspension stress depends on not only the local average total stresslet-the sum of symmetric first moments of both the hydrodynamic traction and the interparticle force-but also on the average quadrupole, octupole, and higher-order moments. To compute the average moments, we formulate a six dimensional Smoluchowski equation governing the microstructural evolution of a suspension in an arbitrary fluid velocity field. Under the conditions of rheologically slow flow, where the Brownian relaxation of the particles is much faster than the spatiotemporal evolution of the flow, the Smoluchowski equation permits asymptotic solution, revealing a suspension stress that follows a second-order fluid constitutive model. We obtain a reciprocal theorem and utilize it to show that all constitutive parameters of the second-order fluid model may be obtained from two simpler linear-response problems: a suspension undergoing simple shear and a suspension undergoing isotropic expansion. The consequences of relaxing the assumption of rheologically slow flow, including the appearance of memory and microcontinuum behaviors, are discussed.

A unified approach to fluid-flow, geomechanical, and seismic modelling

NASA Astrophysics Data System (ADS)

Yarushina, Viktoriya; Minakov, Alexander

2016-04-01

The perturbations of pore pressure can generate seismicity. This is supported by observations from human activities that involve fluid injection into rocks at high pressure (hydraulic fracturing, CO2 storage, geothermal energy production) and natural examples such as volcanic earthquakes. Although the seismic signals that emerge during geotechnical operations are small both in amplitude and duration when compared to natural counterparts. A possible explanation for the earthquake source mechanism is based on a number of in situ stress measurements suggesting that the crustal rocks are close to its plastic yield limit. Hence, a rapid increase of the pore pressure decreases the effective normal stress, and, thus, can trigger seismic shear deformation. At the same time, little attention has been paid to the fact that the perturbation of fluid pressure itself represents an acoustic source. Moreover, non-double-couple source mechanisms are frequently reported from the analysis of microseismicity. A consistent formulation of the source mechanism describing microseismic events should include both a shear and isotropic component. Thus, improved understanding of the interaction between fluid flow and seismic deformation is needed. With this study we aim to increase the competence in integrating real-time microseismic monitoring with geomechanical modelling such that there is a feedback loop between monitored deformation and stress field modelling. We propose fully integrated seismic, geomechanical and reservoir modelling. Our mathematical formulation is based on fundamental set of force balance, mass balance, and constitutive poro-elastoplastic equations for two-phase media consisting of deformable solid rock frame and viscous fluid. We consider a simplified 1D modelling setup for consistent acoustic source and wave propagation in poro-elastoplastic media. In this formulation the seismic wave is generated due to local changes of the stress field and pore pressure induced by e.g. fault generation or strain localization. This approach gives unified framework to characterize microseismicity of both class-I (pressure induced) and class-II (stress triggered) type of events. We consider two modelling setups. In the first setup the event is located within the reservoir and associated with pressure/stress drop due to fracture initiation. In the second setup we assume that seismic wave from a distant source hits a reservoir. The unified formulation of poro-elastoplastic deformation allows us to link the macroscopic stresses to local seismic instability.

Predicting NonInertial Effects with Algebraic Stress Models which Account for Dissipation Rate Anisotropies

NASA Technical Reports Server (NTRS)

Jongen, T.; Machiels, L.; Gatski, T. B.

1997-01-01

Three types of turbulence models which account for rotational effects in noninertial frames of reference are evaluated for the case of incompressible, fully developed rotating turbulent channel flow. The different types of models are a Coriolis-modified eddy-viscosity model, a realizable algebraic stress model, and an algebraic stress model which accounts for dissipation rate anisotropies. A direct numerical simulation of a rotating channel flow is used for the turbulent model validation. This simulation differs from previous studies in that significantly higher rotation numbers are investigated. Flows at these higher rotation numbers are characterized by a relaminarization on the cyclonic or suction side of the channel, and a linear velocity profile on the anticyclonic or pressure side of the channel. The predictive performance of the three types of models are examined in detail, and formulation deficiencies are identified which cause poor predictive performance for some of the models. Criteria are identified which allow for accurate prediction of such flows by algebraic stress models and their corresponding Reynolds stress formulations.

The effect of abdominal pressure on urinary flow rate.

PubMed

Hasegawa, N; Kitagawa, Y; Takasaki, N; Miyazaki, S

1983-07-01

We examined the effect of abdominal pressure on urinary flow rate and urethral closure pressure in 46 subjects, ranging in age from 26 to 82 years. An increase in urinary flow rate caused by abdominal straining was not found when organic obstruction was present in the prostatic urethra in men or the proximal urethra in women, or when dysuria is caused by the lowered detrusor pressure. An increase in urinary flow rate caused by straining was noted when anterior urethral stricture or stress incontinence was present. The increase in urinary flow rate owing to straining was undetermined in the control group. The urethral closure pressure on the anti-stress incontinence zone increased as a result of straining at the same time and to the same degree as did the intravesical pressure. When the anti-stress incontinence zone was subjected to transurethral resection for canal formation urination became possible as a result of straining. The patients who were able to urinate with straining sometimes suffered temporary stress incontinence. The degree of straining did not determine whether the patient could urinate with straining. Therefore, it was concluded that abdominal pressure should be excluded from intravesical pressure in performing several urodynamic studies on the lower urinary tract, such as pressure flow studies, and that it is important to have a sufficient canal formation in the anti-stress incontinence zone when urination with straining is expected when performing an operation on patients with urethral obstruction in the anti-stress incontinence zone.

Gas flow-field induced director alignment in polymer dispersed liquid crystal microdroplets deposited on a glass substrate

NASA Technical Reports Server (NTRS)

Parmar, D. S.; Singh, J. J.

1993-01-01

Polymer dispersed liquid crystal thin films have been deposited on glass substrates by the processes of polymerization and solvent evaporation induced phase separation. The electron and the optical polarization microscopies of the films reveal that PDLC microdroplets formed during the process of phase separation near the top surface of the film remain exposed and respond to shear stress due to air or gas flow on the surface. Optical response of the film to an air flow-induced shear stress input on the free surface has been measured. Director orientation in the droplets changes with the applied shear stress leading to time varying transmitted light intensity. Director dynamics of the droplet for an applied step shear stress has been discussed from free energy considerations. Results on the measurement of light transmission as a function of the gas flow parameter unambiguously demonstrate the potential of these systems for use as boundary layer and gas flow sensors.

Impact of oxygen precursor flow on the forward bias behavior of MOCVD-Al2O3 dielectrics grown on GaN

NASA Astrophysics Data System (ADS)

Chan, Silvia H.; Bisi, Davide; Liu, Xiang; Yeluri, Ramya; Tahhan, Maher; Keller, Stacia; DenBaars, Steven P.; Meneghini, Matteo; Mishra, Umesh K.

2017-11-01

This paper investigates the effects of the oxygen precursor flow supplied during metalorganic chemical vapor deposition (MOCVD) of Al2O3 films on the forward bias behavior of Al2O3/GaN metal-oxide-semiconductor capacitors. The low oxygen flow (100 sccm) delivered during the in situ growth of Al2O3 on GaN resulted in films that exhibited a stable capacitance under forward stress, a lower density of stress-generated negative fixed charges, and a higher dielectric breakdown strength compared to Al2O3 films grown under high oxygen flow (480 sccm). The low oxygen grown Al2O3 dielectrics exhibited lower gate current transients in stress/recovery measurements, providing evidence of a reduced density of trap states near the GaN conduction band and an enhanced robustness under accumulated gate stress. This work reveals oxygen flow variance in MOCVD to be a strategy for controlling the dielectric properties and performance.

Numerical simulations of stick-slip in fluid saturated granular fault gouge

NASA Astrophysics Data System (ADS)

Dorostkar, O.; Johnson, P. A.; Guyer, R. A.; Marone, C.; Carmeliet, J.

2016-12-01

Fluids play a key role in determining the frictional strength and stability of faults. For example, fluid flow and fluid-solid interaction in fault gouge can trigger seismicity, alter earthquake nucleation properties and cause fault zone weakening. We present results of 3D numerical simulations of stick-slip behavior in dry and saturated granular fault gouge. In the saturated case, the gouge is fully saturated and drainage is possible through the boundaries. We model the solid phase (particles) with the discrete element method (DEM) while the fluid is described by the Navier-Stokes equations and solved by computational fluid dynamics (CFD). In our model, granular gouge is sheared between two rough plates under boundary conditions of constant normal stress and constant shearing velocity at the layer boundaries. A phase-space study including shearing velocity and normal stress is taken to identify the conditions for stick-slip regime. We analyzed slip events for dry and saturated cases to determine shear stress drop, released kinetic energy and compaction. The presence of fluid tends to cause larger slip events. We observe a close correlation between the kinetic energy of the particles and of the fluid. In short, during slip, fluid flow induced by the failure and compaction of the granular system, mobilizes the particles, which increases their kinetic energy, leading to greater slip. We further observe that the solid-fluid interaction forces are equal or larger than the solid-solid interaction forces during the slip event, indicating the important influence of the fluid on the granular system. Our simulations can explain the behaviors observed in experimental studies and we are working to apply our results to tectonic faults.

Combined structural analysis and dating of authigenic/synkinematic illite: A step towards unravelling brittle faulting processes in time and space

NASA Astrophysics Data System (ADS)

Viola, Giulio

2017-04-01

Faulting accommodates momentous deformation and its style reflects the complex interplay of often transient processes such as friction, fluid flow and rheological changes within generally dilatant systems. Brittle faults are thus unique archives of the stress state and the physical and chemical conditions at the time of both initial strain localization and subsequent slip(s) during structural reactivation. Opening those archives, however, may be challenging due to the commonly convoluted (if not even chaotic) nature of brittle fault architectures and fault rocks. This is because, once formed, faults are extremely sensitive to variations in stress field and environmental conditions and are prone to readily slip in a variety of conditions, also in regions affected by only weak, far-field stresses. The detailed, multi-scalar structural analysis of faults and of fault rocks has to be the starting point for any study aiming at reconstructing the complex framework of brittle deformation. However, considering that present-day exposures of faults only represent the end result of the faults' often protracted and heterogeneous histories, the obtained structural and mechanical results have to be integrated over the life span of the studied fault system. Dating of synkinematic illite/muscovite to constrain the time-integrated evolution of faults is therefore the natural addition to detailed structural studies. By means of selected examples it will be demonstrated how careful structural analysis integrated with illite characterization and K-Ar dating allows the high-resolution reconstruction of brittle deformation histories and, in turn, multiple constraints to be placed on strain localization, deformation mechanisms, fluid flow, mineral alteration and authigenesis within actively deforming brittle fault rocks. Complex and long brittle histories can thus be reconstructed and untangled in any tectonic setting.

Local probing by use of transparent model materials

NASA Astrophysics Data System (ADS)

Philippe, P.

2017-12-01

The present contribution emphasizes on two distinct examples the benefit with using transparent materials that enable direct visualization within different types of model systems. Our first use of transparent materials investigates the elementary mechanisms involved in soil erosion based on three key ingredients: a) cohesive model materials (i.e. glass beads bonded by solid bridges); b) optical techniques (Refractive Index Matching and Planar Laser Induced Fluorescence [1,2]) ; c) specific mechanical tests to estimate the mechanical strength of the solid bonds. Then, critical shear-stress at erosion onset can be related to tensile strength considering an extension of the classical Shields' number [3,4].Our second example uses a transparent elasto-visco-plastic fluid (Carbopol) as a model of debris flows. Different geometrical configurations allow for an accurate investigation of the flow over an obstacle [5] or a cavity [6], inducing the existence of a dead-zone and consequently of a frontier between solid-like and fluid-like regions that is of particular relevance for debris flows mobilization and deposition. Practically, the hydrodynamics of the flow is investigated by means of high-resolution optical velocimetry (PIV) and underlines a non-monotonous evolution of the shear rate, which increases from zero at the solid-liquid interface, passes through a peak (sometimes leveling off at its maximum value), and returns to zero in a plug zone sufficiently far above the cavity or the obstacle. [1] Philippe P., and Badiane M. Phys. Rev. E 87, 042206 (2013). [2] Dijksman J.A., Rietz F., Lorincz K.A., van Hecke M., and Losert W. Review of Scientific Instruments 83(1), 011301 (2012). [3] Badr S., Gauthier G., and Gondret P. Phys. Fluids 26:023302 (2014). [4] Brunier-Coulin F., Cuéllar P., and Philippe P. Phys. Rev. Fluids 87, 2: 034302 (2017). [5] Luu L.-H., Philippe P., and Chambon G. Phys. Rev. E 91, 013013 (2015). [6] Luu L.-H., Philippe P.; and Chambon G. Journal of Non-Newtonian Fluid Mechanics 245, 25-37 (2017).

Fatigue life prediction in bending from axial fatigue information

NASA Technical Reports Server (NTRS)

Manson, S. S.; Muralidharan, U.

1982-01-01

Bending fatigue in the low cyclic life range differs from axial fatigue due to the plastic flow which alters the linear stress-strain relation normally used to determine the nominal stresses. An approach is presented to take into account the plastic flow in calculating nominal bending stress (S sub bending) based on true surface stress. These functions are derived in closed form for rectangular and circular cross sections. The nominal bending stress and the axial fatigue stress are plotted as a function of life (N sub S) and these curves are shown for several materials of engineering interest.

Investigation of Thermal Stress Convection in Nonisothermal Gases Under Microgravity Conditions

NASA Technical Reports Server (NTRS)

Mackowski, Daniel W.; Knight, Roy W.

1996-01-01

Microgravity conditions offer an environment in which convection in a nonisothermal gas could be driven primarily by thermal stress. A direct examination of thermal stress flows would be invaluable in assessing the accuracy of the Burnett terms in the fluid stress tensor. We present a preliminary numerical investigation of the competing effects of thermal stress, thermal creep at the side walls, and buoyancy on gas convection in nonuniformly heated containers under normal and reduced gravity levels. Conditions in which thermal stress convection becomes dominant are identified, and issues regarding the experimental measurement of the flows are discussed.

Interaction between a normal shock wave and a turbulent boundary layer at high transonic speeds. Part 2: Wall shear stress

NASA Technical Reports Server (NTRS)

Liou, M. S.; Adamson, T. C., Jr.

1979-01-01

An analysis is presented of the flow in the two inner layers, the Reynolds stress sublayer and the wall layer. Included is the calculation of the shear stress at the wall in the interaction region. The limit processes considered are those used for an inviscid flow.

Modeling changes in rill erodibility and critical shear stress on native surface roads

Treesearch

Randy B. Foltz; Hakjun Rhee; William J. Elliot

2008-01-01

This study investigated the effect of cumulative overland flow on rill erodibility and critical shear stress on native surface roads in central Idaho. Rill erodibility decreased exponentially with increasing cumulative overland flow depth; however, critical shear stress did not change. The study demonstrated that road erodibility on the studied road changes over the...

Stability analysis of rimming flow inside a horizontally rotating cylinder in the presence of an insoluble surfactant

NASA Astrophysics Data System (ADS)

Kumawat, Tara Chand; Tiwari, Naveen

2017-12-01

Two-dimensional base state solutions for rimming flows and their stability analysis to small axial perturbations are analyzed numerically. A thin liquid film which is uniformly covered with an insoluble surfactant flows inside a counterclockwise rotating horizontal cylinder. In the present work, a mathematical model is obtained which consists of coupled thin film thickness and surfactant concentration evolution equations. The governing equations are obtained by simplifying the momentum and species transport equations using the thin-film approximation. The model equations include the effect of gravity, viscosity, capillarity, inertia, and Marangoni stress. The concentration gradients generated due to flow result in the surface tension gradient that generates the Marangoni stress near the interface region. The oscillations in the flow due to inertia are damped out by the Marangoni stress. It is observed that the Marangoni stress has stabilizing effect, whereas inertia and surface tension enhance the instability growth rate. In the presence of low diffusion of the surfactant or large value of the Péclet number, the Marangoni stress becomes more effective. The analytically obtained eigenvalues match well with the numerically computed eigenvalues in the absence of gravity.

On the determination of a generalized Darcy equation for yield stress fluid in porous media using a LB TRT scheme

NASA Astrophysics Data System (ADS)

Talon, Laurent; Chevalier, Thibaud

2014-11-01

Non-Newtonian fluids have practical applications in very different domains. Indeed, polymer mixture, paints, slurries, colloidal suspensions, emulsions, foams or heavy oil present complex rheologies. Among the large number of different non-Newtonian fluids an important class of behavior is represented by the yield-stress fluids, viz. fluids that require a minimum of stress to flow. Yield stress fluids are usually modelled as a Bingham fluid or by the Herschel-Bulkley equation. However, simulating flow of a Bingham fluid in porous media still remains a challenging task as the yield stress may significantly alter the numerical stability and precision. In the present work, we use a Lattice-Boltzmann TRT scheme to determine this type of flow in a synthetic porous medium or fracture. Different pressure drops ΔP have been applied in order to derive a generalization of the Darcy's equation. Three different scaling regimes can be distinguished when plotting the dimensionless flow rate q as function of the distance to the critical pressure ΔP - ΔPc . In this presentation, we will investigate the importance of the heterogeneities on those flowing regimes. ANR-12-MONU-0011.

Comparison of gravimetric and mantle flow solutions for sub-lithopsheric stress modeling and their combination

NASA Astrophysics Data System (ADS)

Eshagh, Mehdi; Steinberger, Bernhard; Tenzer, Robert; Tassara, Andrés

2018-05-01

Based on Hager and O'Connell's solution to mantle flow equations, the stresses induced by mantle convection are determined using the density and viscosity structure in addition to topographic data and a plate velocity model. The solution to mantle flow equations requires the knowledge of mantle properties that are typically retrieved from seismic information. Large parts of the world are, however, not yet covered sufficiently by seismic surveys. An alternative method of modeling the stress field was introduced by Runcorn. He formulated a direct relation between the stress field and gravity data, while adopting several assumptions, particularly disregarding the toroidal mantle flow component and mantle viscosity variations. A possible way to overcome theoretical deficiencies of Runcorn's theory as well as some practical limitations of applying Hager and O'Connell's theory (in the absence of seismic data) is to combine these two methods. In this study, we apply a least-squares analysis to combine these two methods based on the gravity data inversion constraint on mantle flow equations. In particular, we use vertical gravity gradients from the Gravity field and steady state Ocean Circulation Explorer that are corrected for the gravitational contribution of crustal density heterogeneities prior to applying a localized gravity-gradient inversion. This gravitational contribution is estimated based on combining the Vening Meinesz-Moritz and flexural isostatic theories. Moreover, we treat the non-isostatic effect implicitly by applying a band-limited kernel of the integral equation during the inversion. In numerical studies of modeling, the stress field within the South American continental lithosphere we compare the results obtained after applying Runcorn and Hager and O'Connell's methods as well as their combination. The results show that, according to Hager and O'Connell's (mantle flow) solution, the maximum stress intensity is inferred under the northern Andes. Additional large stress anomalies are detected along the central and southern Andes, while stresses under most of old, stable cratonic formations are much less pronounced or absent. A prevailing stress-vector orientation realistically resembles a convergent mantle flow and downward currents under continental basins that separate Andean Orogeny from the Amazonian Shield and adjacent cratons. Runcorn's (gravimetric) solution, on the other hand, reflects a tectonic response of the lithosphere to mantle flow, with the maximum stress intensity detected along the subduction zone between the Nazca and Altiplano plates and along the convergent tectonic margin between the Altiplano and South American plates. The results also reveal a very close agreement between the results obtained from the combined and Hager and O'Connell's solutions.

Polyaxial stress-dependent permeability of a three-dimensional fractured rock layer

NASA Astrophysics Data System (ADS)

Lei, Qinghua; Wang, Xiaoguang; Xiang, Jiansheng; Latham, John-Paul

2017-12-01

A study about the influence of polyaxial (true-triaxial) stresses on the permeability of a three-dimensional (3D) fractured rock layer is presented. The 3D fracture system is constructed by extruding a two-dimensional (2D) outcrop pattern of a limestone bed that exhibits a ladder structure consisting of a "through-going" joint set abutted by later-stage short fractures. Geomechanical behaviour of the 3D fractured rock in response to in-situ stresses is modelled by the finite-discrete element method, which can capture the deformation of matrix blocks, variation of stress fields, reactivation of pre-existing rough fractures and propagation of new cracks. A series of numerical simulations is designed to load the fractured rock using various polyaxial in-situ stresses and the stress-dependent flow properties are further calculated. The fractured layer tends to exhibit stronger flow localisation and higher equivalent permeability as the far-field stress ratio is increased and the stress field is rotated such that fractures are preferentially oriented for shearing. The shear dilation of pre-existing fractures has dominant effects on flow localisation in the system, while the propagation of new fractures has minor impacts. The role of the overburden stress suggests that the conventional 2D analysis that neglects the effect of the out-of-plane stress (perpendicular to the bedding interface) may provide indicative approximations but not fully capture the polyaxial stress-dependent fracture network behaviour. The results of this study have important implications for understanding the heterogeneous flow of geological fluids (e.g. groundwater, petroleum) in subsurface and upscaling permeability for large-scale assessments.

Stress loading from viscous flow in the lower crust and triggering of aftershocks following the 1994 Northridge, California, earthquake

USGS Publications Warehouse

Deng, J.; Hudnut, K.; Gurnis, M.; Hauksson, E.

1999-01-01

Following the M(w) 6.7 Northridge earthquake, significant postseismic displacements were resolved with GPS. Using a three-dimensional viscoelastic model, we suggest that this deformation is mainly driven by viscous flow in the lower crust. Such flow can transfer stress to the upper crust and load the rupture zone of the main shock at a decaying rate. Most aftershocks within the rupture zone, especially those that occurred after the first several weeks of the main shock, may have been triggered by continuous stress loading from viscous flow. The long-term decay time of aftershocks (about 2 years) approximately matches the decay of viscoelastic loading, and thus is controlled by the viscosity of the lower crust. Our model provides a physical interpretation of the observed correlation between aftershock decay rate and surface heat flow.Following the Mw 6.7 Northridge earthquake, significant postseismic displacements were resolved with GPS. Using a three-dimensional viscoelastic model, we suggest that this deformation is mainly driven by viscous flow in the lower crust. Such flow can transfer stress to the upper crust and load the rupture zone of the main shock at a decaying rate. Most aftershocks within the rupture zone, especially those that occurred after the first several weeks of the main shock, may have been triggered by continuous stress loading from viscous flow. The long-term decay time of aftershocks (about 2 years) approximately matches the decay of viscoelastic loading, and thus is controlled by the viscosity of the lower crust. Our model provides a physical interpretation of the observed correlation between aftershock decay rate and surface heat flow.

Exact solutions for oscillatory shear sweep behaviors of complex fluids from the Oldroyd 8-constant framework

NASA Astrophysics Data System (ADS)

Saengow, Chaimongkol; Giacomin, A. Jeffrey

2018-03-01

In this paper, we provide a new exact framework for analyzing the most commonly measured behaviors in large-amplitude oscillatory shear flow (LAOS), a popular flow for studying the nonlinear physics of complex fluids. Specifically, the strain rate sweep (also called the strain sweep) is used routinely to identify the onset of nonlinearity. By the strain rate sweep, we mean a sequence of LAOS experiments conducted at the same frequency, performed one after another, with increasing shear rate amplitude. In this paper, we give exact expressions for the nonlinear complex viscosity and the corresponding nonlinear complex normal stress coefficients, for the Oldroyd 8-constant framework for oscillatory shear sweeps. We choose the Oldroyd 8-constant framework for its rich diversity of popular special cases (we list 18 of these). We evaluate the Fourier integrals of our previous exact solution to get exact expressions for the real and imaginary parts of the complex viscosity, and for the complex normal stress coefficients, as functions of both test frequency and shear rate amplitude. We explore the role of infinite shear rate viscosity on strain rate sweep responses for the special case of the corotational Jeffreys fluid. We find that raising η∞ raises the real part of the complex viscosity and lowers the imaginary. In our worked examples, we thus first use the corotational Jeffreys fluid, and then, for greater accuracy, we use the Johnson-Segalman fluid, to describe the strain rate sweep response of molten atactic polystyrene. For our comparisons with data, we use the Spriggs relations to generalize the Oldroyd 8-constant framework to multimode. Our generalization yields unequivocally, a longest fluid relaxation time, used to assign Weissenberg and Deborah numbers to each oscillatory shear flow experiment. We then locate each experiment in the Pipkin space.

Physical consistency of subgrid-scale models for large-eddy simulation of incompressible turbulent flows

NASA Astrophysics Data System (ADS)

Silvis, Maurits H.; Remmerswaal, Ronald A.; Verstappen, Roel

2017-01-01

We study the construction of subgrid-scale models for large-eddy simulation of incompressible turbulent flows. In particular, we aim to consolidate a systematic approach of constructing subgrid-scale models, based on the idea that it is desirable that subgrid-scale models are consistent with the mathematical and physical properties of the Navier-Stokes equations and the turbulent stresses. To that end, we first discuss in detail the symmetries of the Navier-Stokes equations, and the near-wall scaling behavior, realizability and dissipation properties of the turbulent stresses. We furthermore summarize the requirements that subgrid-scale models have to satisfy in order to preserve these important mathematical and physical properties. In this fashion, a framework of model constraints arises that we apply to analyze the behavior of a number of existing subgrid-scale models that are based on the local velocity gradient. We show that these subgrid-scale models do not satisfy all the desired properties, after which we explain that this is partly due to incompatibilities between model constraints and limitations of velocity-gradient-based subgrid-scale models. However, we also reason that the current framework shows that there is room for improvement in the properties and, hence, the behavior of existing subgrid-scale models. We furthermore show how compatible model constraints can be combined to construct new subgrid-scale models that have desirable properties built into them. We provide a few examples of such new models, of which a new model of eddy viscosity type, that is based on the vortex stretching magnitude, is successfully tested in large-eddy simulations of decaying homogeneous isotropic turbulence and turbulent plane-channel flow.

Measuring heterogenous stress fields in a 3D colloidal glass

NASA Astrophysics Data System (ADS)

Lin, Neil; Bierbaum, Matthew; Bi, Max; Sethna, James; Cohen, Itai

Glass in our common experience is hard and fragile. But it still bends, yields, and flows slowly under loads. The yielding of glass, a well documented yet not fully understood flow behavior, is governed by the heterogenous local stresses in the material. While resolving stresses at the atomic scale is not feasible, measurements of stresses at the single particle level in colloidal glasses, a widely used model system for atomic glasses, has recently been made possible using Stress Assessment from Local Structural Anisotropy (SALSA). In this work, we use SALSA to visualize the three dimensional stress network in a hard-sphere glass during start-up shear. By measuring the evolution of this stress network we identify local-yielding. We find that these local-yielding events often require only minimal structural rearrangement and as such have most likely been ignored in previous analyses. We then relate these micro-scale yielding events to the macro-scale flow behavior observed using bulk measurements.

Computational analysis of microbubble flows in bifurcating airways: role of gravity, inertia, and surface tension.

PubMed

Chen, Xiaodong; Zielinski, Rachel; Ghadiali, Samir N

2014-10-01

Although mechanical ventilation is a life-saving therapy for patients with severe lung disorders, the microbubble flows generated during ventilation generate hydrodynamic stresses, including pressure and shear stress gradients, which damage the pulmonary epithelium. In this study, we used computational fluid dynamics to investigate how gravity, inertia, and surface tension influence both microbubble flow patterns in bifurcating airways and the magnitude/distribution of hydrodynamic stresses on the airway wall. Direct interface tracking and finite element techniques were used to simulate bubble propagation in a two-dimensional (2D) liquid-filled bifurcating airway. Computational solutions of the full incompressible Navier-Stokes equation were used to investigate how inertia, gravity, and surface tension forces as characterized by the Reynolds (Re), Bond (Bo), and Capillary (Ca) numbers influence pressure and shear stress gradients at the airway wall. Gravity had a significant impact on flow patterns and hydrodynamic stress magnitudes where Bo > 1 led to dramatic changes in bubble shape and increased pressure and shear stress gradients in the upper daughter airway. Interestingly, increased pressure gradients near the bifurcation point (i.e., carina) were only elevated during asymmetric bubble splitting. Although changes in pressure gradient magnitudes were generally more sensitive to Ca, under large Re conditions, both Re and Ca significantly altered the pressure gradient magnitude. We conclude that inertia, gravity, and surface tension can all have a significant impact on microbubble flow patterns and hydrodynamic stresses in bifurcating airways.

Fluid Mechanics, Arterial Disease, and Gene Expression.

PubMed

Tarbell, John M; Shi, Zhong-Dong; Dunn, Jessilyn; Jo, Hanjoong

2014-01-01

This review places modern research developments in vascular mechanobiology in the context of hemodynamic phenomena in the cardiovascular system and the discrete localization of vascular disease. The modern origins of this field are traced, beginning in the 1960s when associations between flow characteristics, particularly blood flow-induced wall shear stress, and the localization of atherosclerotic plaques were uncovered, and continuing to fluid shear stress effects on the vascular lining endothelial) cells (ECs), including their effects on EC morphology, biochemical production, and gene expression. The earliest single-gene studies and genome-wide analyses are considered. The final section moves from the ECs lining the vessel wall to the smooth muscle cells and fibroblasts within the wall that are fluid me chanically activated by interstitial flow that imposes shear stresses on their surfaces comparable with those of flowing blood on EC surfaces. Interstitial flow stimulates biochemical production and gene expression, much like blood flow on ECs.

Irreducible Representations of Oscillatory and Swirling Flows in Active Soft Matter

NASA Astrophysics Data System (ADS)

Ghose, Somdeb; Adhikari, R.

2014-03-01

Recent experiments imaging fluid flow around swimming microorganisms have revealed complex time-dependent velocity fields that differ qualitatively from the stresslet flow commonly employed in theoretical descriptions of active matter. Here we obtain the most general flow around a finite sized active particle by expanding the surface stress in irreducible Cartesian tensors. This expansion, whose first term is the stresslet, must include, respectively, third-rank polar and axial tensors to minimally capture crucial features of the active oscillatory flow around translating Chlamydomonas and the active swirling flow around rotating Volvox. The representation provides explicit expressions for the irreducible symmetric, antisymmetric, and isotropic parts of the continuum active stress. Antisymmetric active stresses do not conserve orbital angular momentum and our work thus shows that spin angular momentum is necessary to restore angular momentum conservation in continuum hydrodynamic descriptions of active soft matter.

[Effect of caffeine on myocardial blood flow during pharmacological vasodilation].

PubMed

Wielepp, J P; Fricke, E; Horstkotte, D; Burchert, W

2005-02-01

Pharmacologic stress with adenosine is frequently used for noninvasive detection of coronary artery disease. Dietary intake of caffeinated food, beverages or medications might alter adenosine-induced hyperemic blood flow, thereby compromising the diagnostic sensitivity of adenosine stress testing. In this case we report on a male patient with CAD. Myocardial blood flow at rest and during adenosine-induced hyperemia 2 hours after consumption of decaffeinated coffee and again without caffeine intake were quantified by ammonia PET. After caffeine intake there was a clearly diminished increase of myocardial blood flow during adenosine. The average coronary flow reserve in the myocardium was 1.3 after caffeine. In the baseline study without caffeine the coronary flow reserve has been improved to 2.3. Caffeine intake alters the coronary vasodilatory capacity. These findings emphasize the importance of carefully screening patients for intake of caffeinated food prior to adenosine stress testing.

Balancing food security and water demand for freshwater ecosystems

NASA Astrophysics Data System (ADS)

Pastor, Amandine; Palazzo, Amanda; Havlik, Petr; Obersteiner, Michael; Biemans, Hester; Wada, Yoshihide; Kabat, Pavel; Ludwig, Fulco

2017-04-01

Water is not an infinite resource and demand from irrigation, household and industry is constantly increasing. This study focused on including global water availability including environmental flow requirements with water withdrawal from irrigation and other sectors at a monthly time-step in the GLOBIOM model. This model allows re-adjustment of land-use allocation, crop management, consumption and international trade. The GLOBIOM model induces an endogenous change in water price depending on water supply and demand. In this study, the focus was on how the inclusion of water resources affects land-use and, in particular, how global change will influence repartition of irrigated and rainfed lands at global scale. We used the climate change scenario including a radiative forcing of 8.5 W/m2 (RCP8.5), the socio-economic scenario (SSP2: middle-of-road), and the environmental flow method based on monthly flow allocation (the Variable Monthly Flow method) with high and low restrictions. Irrigation withdrawals were adjusted to a monthly time-step to account for biophysical water limitations at finer time resolution. Our results show that irrigated land might decrease up to 40% on average depending on the choice of EFR restrictions. Several areas were identified as future hot-spots of water stress such as the Mediterranean and Middle-East regions. Other countries were identified to be in safe position in terms of water stress such as North-European countries. Re-allocation of rainfed and irrigated land might be useful information for land-use planners and water managers at an international level to decide on appropriate legislations on climate change mitigation/adaptation when exposure and sensitivity to climate change is high and/or on adaptation measures to face increasing water demand. For example, some countries are likely to adopt measures to increase their water use efficiencies (irrigation system, soil and water conservation practices) to face water shortages, while others might consider improving their trade policy to avoid food shortage.

Rheology of Diabase: Implications for Tectonics on Venus and Mars

NASA Technical Reports Server (NTRS)

Kohlstedt, David L.

2001-01-01

Two important goals of our experimental investigation of the rheological behavior of diabase rocks were: (1) to determine flow laws describing their creep behavior over wide ranges of temperature, stress and strain rate and (2) to develop an understanding of the physical mechanisms by which these rocks flow under laboratory conditions. With this basis, a primary objective then was to construct constitutive equations that can be used to extrapolate from laboratory to planetary conditions. We specifically studied the rheological properties of both natural rock samples and synthetic aggregates. The former provided constraints for geologic systems, while the latter defined the relative contributions of the constituent mineral phases and avoided the influence of glass/melt found in natural samples. In addition, partially molten samples of crustal rock composition were deformed in shear to large strains (greater than 200%) important in crustal environments. The results of this research yielded essential rheological properties essential for models of crustal deformation on terrestrial planets, specifically Venus and Mars, as well as on the geodynamical evolution of these planets. Over the past three years, we also completed our investigation of the creep behavior of water ice with applications to the glaciers, ice sheets and icy satellites. Constitutive equations were determined that describe flow over a wide ranged of stress, strain rate, grain size and temperature. In the case of ice, three creep regimes were delineate. Extrapolation demonstrates that dislocation glide and grain boundary sliding processes dominate flow in ice I under planetary conditions and that diffusion creep is not an important deformation mechanism either in the laboratory or on icy satellites. These results have already been incorporated by other investigators into models describing, for example, the thickness and stability of the ice shell on Europa and to unravel long-standing discrepancies between field observations on glaciers and laboratory results.

Multiscale Particle-Based Modeling of Flowing Platelets in Blood Plasma Using Dissipative Particle Dynamics and Coarse Grained Molecular Dynamics

PubMed Central

Zhang, Peng; Gao, Chao; Zhang, Na; Slepian, Marvin J.; Deng, Yuefan; Bluestein, Danny

2014-01-01

We developed a multiscale particle-based model of platelets, to study the transport dynamics of shear stresses between the surrounding fluid and the platelet membrane. This model facilitates a more accurate prediction of the activation potential of platelets by viscous shear stresses - one of the major mechanisms leading to thrombus formation in cardiovascular diseases and in prosthetic cardiovascular devices. The interface of the model couples coarse-grained molecular dynamics (CGMD) with dissipative particle dynamics (DPD). The CGMD handles individual platelets while the DPD models the macroscopic transport of blood plasma in vessels. A hybrid force field is formulated for establishing a functional interface between the platelet membrane and the surrounding fluid, in which the microstructural changes of platelets may respond to the extracellular viscous shear stresses transferred to them. The interaction between the two systems preserves dynamic properties of the flowing platelets, such as the flipping motion. Using this multiscale particle-based approach, we have further studied the effects of the platelet elastic modulus by comparing the action of the flow-induced shear stresses on rigid and deformable platelet models. The results indicate that neglecting the platelet deformability may overestimate the stress on the platelet membrane, which in turn may lead to erroneous predictions of the platelet activation under viscous shear flow conditions. This particle-based fluid-structure interaction multiscale model offers for the first time a computationally feasible approach for simulating deformable platelets interacting with viscous blood flow, aimed at predicting flow induced platelet activation by using a highly resolved mapping of the stress distribution on the platelet membrane under dynamic flow conditions. PMID:25530818

Why do we live for much less than 100 years? A fluid mechanics view and approach

NASA Astrophysics Data System (ADS)

Messaris, Gerasimos A. T.; Hadjinicolaou, Maria; Karahalios, George T.

2017-08-01

Blood flow in arteries induces shear stresses on the arterial walls. The present work is motivated by the implications of low shear stress on the human arterial system and its effect on the duration of the life of a subject. The low and/or bidirectional wall shear stress stiffens the arterial wall and in synergy with the fluctuating tissue stress due to the fluctuating blood pressure activates the mechanism of aging. If the shear stress were not low and/or bidirectional and if it did not contribute to local endothelium dysfunctions, the tissue stress alone would take more than 100 yr to cause a failure on the human arterial system. Applying the s-n diagram (tissue stress against the number of cycles to failure) to determine the fatigue life of the aorta, for example, we find that in the absence of other pathogenic factors, for a tissue stress 1.2 times bigger than the tissue stress of a non-stiff aorta, the potential 100 yr of life are reduced to nearly 80 yr. Calculation of the rate of variation of the tissue stress of a subject with time may lead to a possible prognosis about the evolution of wall stiffness and its impact on the arterial aging of this subject. Further patient-specific in vivo mechanistic studies complemented by molecular imaging are needed to contribute to the formation of a data base, from which improved models describing the evolution of the arterial stiffness can be developed. Accordingly, the degree of stiffness of the aorta compared with existing data from a corresponding data base may provide with information about the degree of the fatigue of the aortic wall and its possible future behavior and lead to a patient-adapted medical treatment as a means of a would-be preventive medication.

Effect of particle velocity fluctuations on the inertia coupling in two-phase flow

NASA Technical Reports Server (NTRS)

Drew, Donald A.

1989-01-01

Consistent forms for the interfacial force, the interfacial pressure, the Reynolds stresses and the particle stress have been derived for the inviscid, irrotational incompressible flow of fluid in a dilute suspension of spheres. The particles are assumed to have a velocity distribution, giving rise to an effective pressure and stress in the particle phase. The velocity fluctuations also contribute in the fluid Reynolds stress and in the (elastic) stress field inside the spheres. The relation of these constitutive equations to the force on an individual sphere is discussed.

Effects of Disturbed Flow on Vascular Endothelium: Pathophysiological Basis and Clinical Perspectives

PubMed Central

Chiu, Jeng-Jiann; Chien, Shu

2013-01-01

Vascular endothelial cells (ECs) are exposed to hemodynamic forces, which modulate EC functions and vascular biology/pathobiology in health and disease. The flow patterns and hemodynamic forces are not uniform in the vascular system. In straight parts of the arterial tree, blood flow is generally laminar and wall shear stress is high and directed; in branches and curvatures, blood flow is disturbed with nonuniform and irregular distribution of low wall shear stress. Sustained laminar flow with high shear stress upregulates expressions of EC genes and proteins that are protective against atherosclerosis, whereas disturbed flow with associated reciprocating, low shear stress generally upregulates the EC genes and proteins that promote atherogenesis. These findings have led to the concept that the disturbed flow pattern in branch points and curvatures causes the preferential localization of atherosclerotic lesions. Disturbed flow also results in postsurgical neointimal hyperplasia and contributes to pathophysiology of clinical conditions such as in-stent restenosis, vein bypass graft failure, and transplant vasculopathy, as well as aortic valve calcification. In the venous system, disturbed flow resulting from reflux, outflow obstruction, and/or stasis leads to venous inflammation and thrombosis, and hence the development of chronic venous diseases. Understanding of the effects of disturbed flow on ECs can provide mechanistic insights into the role of complex flow patterns in pathogenesis of vascular diseases and can help to elucidate the phenotypic and functional differences between quiescent (nonatherogenic/nonthrombogenic) and activated (atherogenic/thrombogenic) ECs. This review summarizes the current knowledge on the role of disturbed flow in EC physiology and pathophysiology, as well as its clinical implications. Such information can contribute to our understanding of the etiology of lesion development in vascular niches with disturbed flow and help to generate new approaches for therapeutic interventions. PMID:21248169

Three-dimensional flow structure and patterns of bed shear stress in an evolving compound meander bend

USGS Publications Warehouse

Engel, Frank; Rhoads, Bruce L.

2016-01-01

Compound meander bends with multiple lobes of maximum curvature are common in actively evolving lowland rivers. Interaction among spatial patterns of mean flow, turbulence, bed morphology, bank failures and channel migration in compound bends is poorly understood. In this paper, acoustic Doppler current profiler (ADCP) measurements of the three-dimensional (3D) flow velocities in a compound bend are examined to evaluate the influence of channel curvature and hydrologic variability on the structure of flow within the bend. Flow structure at various flow stages is related to changes in bed morphology over the study timeframe. Increases in local curvature within the upstream lobe of the bend reduce outer bank velocities at morphologically significant flows, creating a region that protects the bank from high momentum flow and high bed shear stresses. The dimensionless radius of curvature in the upstream lobe is one-third less than that of the downstream lobe, with average bank erosion rates less than half of the erosion rates for the downstream lobe. Higher bank erosion rates within the downstream lobe correspond to the shift in a core of high velocity and bed shear stresses toward the outer bank as flow moves through the two lobes. These erosion patterns provide a mechanism for continued migration of the downstream lobe in the near future. Bed material size distributions within the bend correspond to spatial patterns of bed shear stress magnitudes, indicating that bed material sorting within the bend is governed by bed shear stress. Results suggest that patterns of flow, sediment entrainment, and planform evolution in compound meander bends are more complex than in simple meander bends. Moreover, interactions among local influences on the flow, such as woody debris, local topographic steering, and locally high curvature, tend to cause compound bends to evolve toward increasing planform complexity over time rather than stable configurations.

Intercomparison of granular stress and turbulence models for unidirectional sheet flow applications

NASA Astrophysics Data System (ADS)

Chauchat, J.; Cheng, Z.; Hsu, T. J.

2016-12-01

The intergranular stresses are one of the key elements in two-phase sediment transport models. There are two main existing approaches, the kinetic theory of granular flows (Jenkins and Hanes, 1998; Hsu et al., 2004) and the phenomenological rheology such as the one proposed by Bagnold (Hanes and Bowen, 1985) or the μ(I) dense granular flow rheology (Revil-Baudard and Chauchat, 2013). Concerning the turbulent Reynolds stress, mixing length and k-ɛ turbulence models have been validated by previous studies (Revil-Baudard and Chauchat, 2013; Hsu et al., 2004). Recently, sedFoam was developed based on kinetic theory of granular flows and k-ɛ turbulence models (Cheng and Hsu, 2014). In this study, we further extended sedFoam by implementing the mixing length and the dense granular flow rheology by following Revil-Baudard and Chauchat (2013). This allows us to objectively compare the different combinations of intergranular stresses (kinetic theory or the dense granular flow rheology) and turbulence models (mixing length or k-ɛ) under unidirectional sheet flow conditions. We found that the calibrated mixing length and k-ɛ models predicts similar velocity and concentration profiles. The differences observed between the kinetic theory and the dense granular flow rheology requires further investigation. In particular, we hypothesize that the extended kinetic theory proposed by Berzi (2011) would probably improve the existing combination of the kinetic theory with a simple Coulomb frictional model in sedFoam. A semi-analytical solution proposed by Berzi and Fraccarollo(2013) for sediment transport rate and sheet layer thickness versus the Shields number is compared with the results obtained by using the dense granular flow rheology and the mixing length model. The results are similar which demonstrate that both the extended kinetic theory and the dense granular flow rheology can be used to model intergranular stresses under sheet flow conditions.

Tracing the Pathway from Drift-Wave Turbulence with Broken Symmetry to the Production of Sheared Axial Mean Flow

NASA Astrophysics Data System (ADS)

Hong, R.; Li, J. C.; Chakraborty Thakur, S.; Hajjar, R.; Diamond, P. H.; Tynan, G. R.

2018-05-01

This study traces the emergence of sheared axial flow from collisional drift-wave turbulence with broken symmetry in a linear plasma device—the controlled shear decorrelation experiment. As the density profile steepens, the axial Reynolds stress develops and drives a radially sheared axial flow that is parallel to the magnetic field. Results show that the nondiffusive piece of the Reynolds stress is driven by the density gradient, results from spectral asymmetry of the turbulence, and, thus, is dynamical in origin. Taken together, these findings constitute the first simultaneous demonstration of the causal link between the density gradient, turbulence, and stress with broken spectral symmetry and the mean axial flow.

Evolution of a Planar Wake in Adverse Pressure Gradient

NASA Technical Reports Server (NTRS)

Driver, David M.; Mateer, George G.

2016-01-01

In the interest of improving the predictability of high-lift systems at maximum lift conditions, a series of fundamental experiments were conducted to study the effects of adverse pressure gradient on a wake flow. Mean and fluctuating velocities were measured with a two-component laser-Doppler velocimeter. Data were obtained for several cases of adverse pressure gradient, producing flows ranging from no reversed flow to massively reversed flow. While the turbulent Reynolds stresses increase with increasing size of the reversed flow region, the gradient of Reynolds stress does not. Computations using various turbulence models were unable to reproduce the reversed flow.

Mean velocities and Reynolds stresses upstream of a simulated wing-fuselage juncture

NASA Technical Reports Server (NTRS)

Mcmahon, H.; Hubbartt, J.; Kubendran, L. R.

1983-01-01

Values of three mean velocity components and six turbulence stresses measured in a turbulent shear layer upstream of a simulated wing-fuselage juncture and immediately downstream of the start of the juncture are presented nd discussed. Two single-sensor hot-wire probes were used in the measurements. The separated region just upstream of the wing contains an area of reversed flow near the fuselage surface where the turbulence level is high. Outside of this area the flow skews as it passes around the body, and in this skewed region the magnitude and distribution of the turbulent normal and shear stresses within the shear layer are modified slightly by the skewing and deceleration of the flow. A short distance downstream of the wing leading edge the secondary flow vortext is tightly rolled up and redistributes both mean flow and turbulence in the juncture. The data acquisition technique employed here allows a hot wire to be used in a reversed flow region to indicate flow direction.

Wall shear stress estimates in coronary artery constrictions

NASA Technical Reports Server (NTRS)

Back, L. H.; Crawford, D. W.

1992-01-01

Wall shear stress estimates from laminar boundary layer theory were found to agree fairly well with the magnitude of shear stress levels along coronary artery constrictions obtained from solutions of the Navier Stokes equations for both steady and pulsatile flow. The relatively simple method can be used for in vivo estimates of wall shear stress in constrictions by using a vessel shape function determined from a coronary angiogram, along with a knowledge of the flow rate.

Modeling the Collisional-Plastic Stress Transition for Bin Discharge of Granular Material

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pannala, Sreekanth; Daw, C Stuart; FINNEY, Charles E A

2009-01-01

We propose a heuristic model for the transition between collisional and frictional/plastic stresses in the flow of granular material. Our approach is based on a physically motivated, nonlinear blending function that produces a weighted average of the limiting stresses, depending on the local void fraction in the flow field. Previously published stress models are utilized to describe the behavior in the collisional (Lun et al., 1984) and quasi-static limits (Schaeffer, 1987 and Syamlal et al., 1993). Sigmoidal and hyperbolic tangent functions are used to mimic the observed smooth yet rapid transition between the collisional and plastic stress zones. We implementmore » our stress transition model in an opensource multiphase flow solver, MFIX (Multiphase Flow with Interphase eXchanges, www.mfix.org) and demonstrate its application to a standard bin discharge problem. The model s effectiveness is illustrated by comparing computational predictions to the experimentally derived Beverloo correlation. With the correct choice of function parameters, the model predicts bin discharge rates within the error margins of the Beverloo correlation and is more accurate than one of the alternative granular stress models proposed in the literature. Although a second granular stress model in the literature is also reasonably consistent with the Beverloo correlation, we propose that our alternative blending function is likely to be more adaptable to situations with more complex solids properties (e.g., sticky solids).« less

Breaking symmetry in non-planar bifurcations: distribution of flow and wall shear stress.

PubMed

Lu, Yiling; Lu, Xiyun; Zhuang, Lixian; Wang, Wen

2002-01-01

Non-planarity in blood vessels is known to influence arterial flows and wall shear stress. To gain insight, computational fluid dynamics (CFD) has been used to investigate effects of curvature and out-of-plane geometry on the distribution of fluid flows and wall shear stresses in a hypothetical non-planar bifurcation. Three-dimensional Navier-Stokes equations for a steady state Newtonian fluid were solved numerically using a finite element method. Non-planarity in one of the two daughter vessels is found to deflect flow from the inner wall of the vessel to the outer wall and to cause changes in the distribution of wall shear stresses. Results from this study agree to experimental observations and CFD simulations in the literature, and support the view that non-planarity in blood vessels is a factor with important haemodynamic significance and may play a key role in vascular biology and pathophysiology.

Satellites Seek Gravity Signals for Remote Sensing the Seismotectonic Stresses in Earth

NASA Technical Reports Server (NTRS)

Liu, Han-Shou; Chen, Jizhong; Li, Jinling

2003-01-01

The ability of the mantle to withstand stress-difference due to superimposed loads would appear to argue against flow in the Earth s mantle, but the ironic fact is that the satellite determined gravity variations are the evidence of density differences associated with mantle flow. The type of flow which is most likely to be involved concerns convection currents. For the past 4 decades, models of mantle convection have made remarkable advancements. Although a large body of evidence regarding the seafloor depth, heat flow, lithospheric strength and forces of slab-pull and swell-push has been obtained, the global seismotectonic stresses in the Earth are yet to be determined. The problem is that no one has been able to come up with a satisfactory scenario that must characterize the stresses in the Earth which cause earthquakes and create tectonic features.

Stress and flow analyses of ultraviolet-curable resin during curing

NASA Astrophysics Data System (ADS)

Umezaki, Eisaku; Okano, Akira; Koyama, Hiroto

2014-06-01

The stress and flow generated in ultraviolet (UV)-curable resin during curing in molds were measured to investigate their relationship. The specimens were molds consisting of glass plates and acrylic bars, and UV-curable liquid resin. The specimens were illuminated from above with UV rays. Photoelastic and visual images were separately obtained at a constant time interval using cameras during curing. To help obtain the visual images, acrylic powder was mixed with the liquid resin. The stress was obtained from the photoelastic images by a digital photoelastic technique with phase stepping, and the flow was obtained from the visual images by a particle-tracking velocimetry technique. Results indicate that the stress generated in the UV-curable resin during curing depends on the degree of contact between the mold and the cured area of the resin, and is hardly related to the flow.

Periodicity and chaos from switched flow systems - Contrasting examples of discretely controlled continuous systems

NASA Technical Reports Server (NTRS)

Chase, Christopher; Serrano, Joseph; Ramadge, Peter J.

1993-01-01

We analyze two examples of the discrete control of a continuous variable system. These examples exhibit what may be regarded as the two extremes of complexity of the closed-loop behavior: one is eventually periodic, the other is chaotic. Our examples are derived from sampled deterministic flow models. These are of interest in their own right but have also been used as models for certain aspects of manufacturing systems. In each case, we give a precise characterization of the closed-loop behavior.

Expression of endothelin-1 and constitutional nitric oxide synthase messenger RNA in saphenous vein endothelial cells exposed to arterial flow shear stress.

PubMed

Zhu, Z G; Li, H H; Zhang, B R

1997-11-01

It has long been speculated that increased blood flow shear stress might be one of the major factors affecting the patency of grafted saphenous vein in coronary artery bypass operations. The underlying cellular and molecular mechanisms for so-called "shear stress damage" have not yet been well elucidated. Endothelial cells harvested from human saphenous vein were cultured in vitro and then exposed to a high arterial level flow shear stress in the parallel flow chamber. The expression levels of endothelin-1 and constitutional nitric oxide synthase by the endothelial cells were evaluated semiquantitatively at the gene transcription (messenger RNA) level using reverse transcription polymerase chain reaction. After 7 hours of exposure to arterial level shear stress, the expression of constitutional nitric oxide synthase messenger RNA by saphenous vein endothelial cells was significantly reduced, whereas the expression of endothelin-1 messenger RNA was substantially increased. These changes were more predominant at 24 hours. Arterial level flow shear stress could cause important changes in the gene transcription level in saphenous vein endothelial cells within a short period of time. The functional alterations of saphenous vein endothelial cells, as manifested by the increased expression of endothelin-1 and decreased expression of nitric oxide synthase messenger RNA, might play a crucial role in the vein graft remodeling process.

Analysis of flow disturbance in a stenosed carotid artery bifurcation using two-equation transitional and turbulence models.

PubMed

Tan, F P P; Soloperto, G; Bashford, S; Wood, N B; Thom, S; Hughes, A; Xu, X Y

2008-12-01

In this study, newly developed two-equation turbulence models and transitional variants are employed for the prediction of blood flow patterns in a diseased carotid artery where the growth, progression, and structure of the plaque at rupture are closely linked to low and oscillating wall shear stresses. Moreover, the laminar-turbulent transition in the poststenotic zone can alter the separation zone length, wall shear stress, and pressure distribution over the plaque, with potential implications for stresses within the plaque. Following the validation with well established experimental measurements and numerical studies, a magnetic-resonance (MR) image-based model of the carotid bifurcation with 70% stenosis was reconstructed and simulated using realistic patient-specific conditions. Laminar flow, a correlation-based transitional version of Menter's hybrid k-epsilon/k-omega shear stress transport (SST) model and its "scale adaptive simulation" (SAS) variant were implemented in pulsatile simulations from which analyses of velocity profiles, wall shear stress, and turbulence intensity were conducted. In general, the transitional version of SST and its SAS variant are shown to give a better overall agreement than their standard counterparts with experimental data for pulsatile flow in an axisymmetric stenosed tube. For the patient-specific case reported, the wall shear stress analysis showed discernable differences between the laminar flow and SST transitional models but virtually no difference between the SST transitional model and its SAS variant.

Grain-size-yield stress relationship: Analysis and computation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Meyers, M.A.; Benson, D.J.; Fu, H.H.

1999-07-01

The seminal contributions of Julia Weertman to the understanding of the mechanical properties of nanocrystalline materials will be briefly outlined. A constitutive equation predicting the effect of grain size on the yield stress of metals, based on the model proposed by M.A. Meyers and E. Ashworth, is discussed and extended to the nanocrystalline regime. At large grain sizes, it has the Hall-Petch form, and in the nanocrystalline domain the slope gradually decreases until it asymptotically approaches the flow stress of the grain boundaries. The material is envisaged as a composite, comprised of the grain interior, with flow stress {sigma}{sub fB},more » and grain boundary work-hardened layer, with flow stress {sigma}{sub fGB}. Three principal factors contribute to the grain-boundary hardening: (1) the grain boundaries act as barriers to plastic flow; (2) the grain boundaries act as dislocation sources; and (3) elastic anisotropy causes additional stresses in grain-boundary surroundings. The predictions of this model are compared with experimental measurements over the mono, micro, and nanocrystalline domains. Computational predictions are made of plastic flow as a function of grain size incorporating elastic and plastic anisotropy as well as differences of dislocation accumulation rate in grain boundary regions and grain interiors. This is the first plasticity calculation that accounts for grain size effects in a physically-based manner. 58 refs., 7 figs., 1 tab.« less

Upslope deposition of extremely distal turbidites: an example from the Tiburon Rise, west-central Atlantic

USGS Publications Warehouse

Dolan, J.; Beck, C.; Ogawa, Y.

1989-01-01

These terrigenous silt and sand turbidities represent an unprecedented example of upslope turbidite deposition in an extremely distral setting. Flow thickness was the dominant control on deposition of these beds, rather than true upslope flow. -from Authors

Dynamics of the blood flow in the curved artery with the rolling massage

NASA Astrophysics Data System (ADS)

Yi, H. H.; Wu, X. H.; Yao, Y. L.

2011-10-01

Arterial wall shear stress and flow velocity are important factors in the development of some arterial diseases. Here, we aim to investigate the dynamic effect of the rolling massage on the property of the blood flow in the curved artery. The distributions of flow velocity and shear stress for the blood flow are computed by the lattice Boltzmann method, and the dynamic factors under different rolling techniques are studied numerically. The study is helpful to understand the mechanism of the massage and develop the massage techniques.

Drag reduction and the dynamics of turbulence in simple and complex fluidsa)

NASA Astrophysics Data System (ADS)

Graham, Michael D.

2014-10-01

Addition of a small amount of very large polymer molecules or micelle-forming surfactants to a liquid can dramatically reduce the energy dissipation it exhibits in the turbulent flow regime. This rheological drag reduction phenomenon is widely used, for example, in the Alaska pipeline, but it is not well-understood, and no comparable technology exists to reduce turbulent energy consumption in flows of gases, in which polymers or surfactants cannot be dissolved. The most striking feature of this phenomenon is the existence of a so-called maximum drag reduction (MDR) asymptote: for a given geometry and driving force, there is a maximum level of drag reduction that can be achieved through addition of polymers. Changing the concentration, molecular weight or even the chemical structure of the additives has little to no effect on this asymptotic value. This universality is the major puzzle of drag reduction. We describe direct numerical simulations of turbulent minimal channel flow of Newtonian fluids and viscoelastic polymer solutions. Even in the absence of polymers, we show that there are intervals of "hibernating" turbulence that display very low drag as well as many other features of the MDR asymptote observed in polymer solutions. As Weissenberg number increases to moderate values the frequency of these intervals also increases, and a simple theory captures key features of the intermittent dynamics observed in the simulations. At higher Weissenberg number, these intervals are altered - for example, their duration becomes substantially longer and the instantaneous Reynolds shear stress during them becomes very small. Additionally, simulations of "edge states," dynamical trajectories that lie on the boundary between turbulent and laminar flow, display characteristics that are similar to those of hibernating turbulence and thus to the MDR asymptote, again even in the absence of polymer additives. Based on these observations, we propose a tentative unified description of rheological drag reduction. The existence of MDR-like intervals even in the absence of additives sheds light on the observed universality of MDR and may ultimately lead to new flow control approaches for improving energy efficiency in a wide range of processes.

Investigation of Wall Shear Stress Behavior for Rough Surfaces with Blowing

NASA Astrophysics Data System (ADS)

Helvey, Jacob; Borchetta, Colby; Miller, Mark; Martin, Alexandre; Bailey, Sean

2014-11-01

We present an experimental study conducted in a turbulent channel flow wind tunnel to determine the modifications made to the turbulent flow over rough surfaces with flow injection through the surfaces. Hot-wire profile results from a quasi-two-dimensional, sinusoidally-rough surface indicate that the effects of roughness are enhanced by momentum injection through the surface. In particular, the wall shear stress was found to show behavior consistent with increased roughness height when surface blowing was increased. This observed behavior contradicts previously reported results for regular three-dimensional roughness which show a decrease in wall shear stress with additional blowing. It is unclear whether this discrepancy is due to differences in the roughness geometry under consideration or the use of the Clauser fit to estimate wall shear stress. Additional PIV experiments are being conducted for a three-dimensional fibrous surface to obtain Reynolds shear stress profiles. These results provide an additional method for estimation of wall-shear stress and thus allow verification of the use of the Clauser chart approach for flows with momentum injection through the surface. This research is supported by NASA Kentucky EPSCoR Award NNX10AV39A, and NASA RA Award NNX13AN04A.

Constitutive modeling of the mechanical behavior of high strength ferritic steels for static and dynamic applications

NASA Astrophysics Data System (ADS)

Abed, Farid H.

2010-11-01

A constitutive relation is presented in this paper to describe the plastic behavior of ferritic steel over a broad range of temperatures and strain rates. The thermo-mechanical behavior of high strength low alloy (HSLA-65) and DH-63 naval structural steels is considered in this study at strains over 40%. The temperatures and strain rates are considered in the range where dynamic strain aging is not effective. The concept of thermal activation analysis as well as the dislocation interaction mechanism is used in developing the flow model for both the isothermal and adiabatic viscoplastic deformation. The flow stresses of the two steels are very sensitive to temperature and strain rate, the yield stresses increase with decreasing temperatures and increasing strain rates. That is, the thermal flow stress is mainly captured by the yield stresses while the hardening stresses are totally pertained to the athermal component of the flow stress. The proposed constitutive model predicts results that compare very well with the measured ones at initial temperature range of 77 K to 1000 K and strain rates between 0.001 s-1 and 8500 s-1 for both steels.

Blood Flow Modulation of Vascular Dynamics

PubMed Central

Lee, Juhyun; Sevag Packard, René R.; Hsiai, Tzung K.

2015-01-01

Purpose of review Blood flow is intimately linked with cardiovascular development, repair, and dysfunction. The current review will build on the fluid mechanical principle underlying hemodynamic shear forces, mechanotransduction, and metabolic effects. Recent findings Pulsatile flow produces both time- (∂τ /∂t)and spatial-varying shear stress (∂τ /∂x) to modulate vascular oxidative stress and inflammatory response with pathophysiological significance to atherosclerosis. The characteristics of hemodynamic shear forces; namely, steady laminar (∂τ /∂t= 0), pulsatile (PSS: unidirectional forward flow), and oscillatory shear stress (OSS: bidirectional with a near net 0 forward flow) modulate mechano-signal transduction to influence metabolic effects on vascular endothelial function. Atheroprotective PSS promotes anti-oxidant, anti-inflammatory, and anti-thrombotic responses, whereas atherogenic OSS induces NADPH oxidase–JNK signaling to increase mitochondrial superoxide production, protein degradation of manganese superoxide dismutase (MnSOD), and post-translational protein modifications of LDL particles in the disturbed flow-exposed regions of vasculature. In the era of tissue regeneration, shear stress has been implicated in re-activation of developmental genes; namely, Wnt and Notch signaling, for vascular development and repair. Summary Blood flow imparts a dynamic continuum from vascular development to repair. Augmentation of PSS confers atheroprotection and re-activation of developmental signaling pathways for regeneration. PMID:26218416

An efficient immersed boundary-lattice Boltzmann method for the hydrodynamic interaction of elastic filaments

PubMed Central

Tian, Fang-Bao; Luo, Haoxiang; Zhu, Luoding; Liao, James C.; Lu, Xi-Yun

2012-01-01

We have introduced a modified penalty approach into the flow-structure interaction solver that combines an immersed boundary method (IBM) and a multi-block lattice Boltzmann method (LBM) to model an incompressible flow and elastic boundaries with finite mass. The effect of the solid structure is handled by the IBM in which the stress exerted by the structure on the fluid is spread onto the collocated grid points near the boundary. The fluid motion is obtained by solving the discrete lattice Boltzmann equation. The inertial force of the thin solid structure is incorporated by connecting this structure through virtual springs to a ghost structure with the equivalent mass. This treatment ameliorates the numerical instability issue encountered in this type of problems. Thanks to the superior efficiency of the IBM and LBM, the overall method is extremely fast for a class of flow-structure interaction problems where details of flow patterns need to be resolved. Numerical examples, including those involving multiple solid bodies, are presented to verify the method and illustrate its efficiency. As an application of the present method, an elastic filament flapping in the Kármán gait and the entrainment regions near a cylinder is studied to model fish swimming in these regions. Significant drag reduction is found for the filament, and the result is consistent with the metabolic cost measured experimentally for the live fish. PMID:23564971

An efficient immersed boundary-lattice Boltzmann method for the hydrodynamic interaction of elastic filaments

NASA Astrophysics Data System (ADS)

Tian, Fang-Bao; Luo, Haoxiang; Zhu, Luoding; Liao, James C.; Lu, Xi-Yun

2011-08-01

We have introduced a modified penalty approach into the flow-structure interaction solver that combines an immersed boundary method (IBM) and a multi-block lattice Boltzmann method (LBM) to model an incompressible flow and elastic boundaries with finite mass. The effect of the solid structure is handled by the IBM in which the stress exerted by the structure on the fluid is spread onto the collocated grid points near the boundary. The fluid motion is obtained by solving the discrete lattice Boltzmann equation. The inertial force of the thin solid structure is incorporated by connecting this structure through virtual springs to a ghost structure with the equivalent mass. This treatment ameliorates the numerical instability issue encountered in this type of problems. Thanks to the superior efficiency of the IBM and LBM, the overall method is extremely fast for a class of flow-structure interaction problems where details of flow patterns need to be resolved. Numerical examples, including those involving multiple solid bodies, are presented to verify the method and illustrate its efficiency. As an application of the present method, an elastic filament flapping in the Kármán gait and the entrainment regions near a cylinder is studied to model fish swimming in these regions. Significant drag reduction is found for the filament, and the result is consistent with the metabolic cost measured experimentally for the live fish.

Numerical investigation on effect of aortic root geometry on flow induced structural stresses developed in a bileaflet mechanical heart valve

NASA Astrophysics Data System (ADS)

Abbas, S. S.; Nasif, M. S.; Said, M. A. M.; Kadhim, S. K.

2017-10-01

Structural stresses developed in an artificial bileaflet mechanical heart valve (BMHV) due to pulsed blood flow may cause valve failure due to yielding. In this paper, von-Mises stresses are computed and compared for BMHV placed in two types of aortic root geometries that are aortic root with axisymmetric sinuses and with axisymmetric bulb, at different physiological blood flow rates. With BMHV placed in an aortic root with axisymmetric sinuses, the von-Mises stresses developed in the valve were found to be up to 47% higher than BMHV placed in aortic root with axisymmetric bulb under similar physiological conditions. High velocity vectors and therefore high von-Mises stresses have been observed for BMHV placed in aortic root with axisymmetric sinuses, that can lead to valve failure.

A robust return-map algorithm for general multisurface plasticity

DOE PAGES

Adhikary, Deepak P.; Jayasundara, Chandana T.; Podgorney, Robert K.; ...

2016-06-16

Three new contributions to the field of multisurface plasticity are presented for general situations with an arbitrary number of nonlinear yield surfaces with hardening or softening. A method for handling linearly dependent flow directions is described. A residual that can be used in a line search is defined. An algorithm that has been implemented and comprehensively tested is discussed in detail. Examples are presented to illustrate the computational cost of various components of the algorithm. The overall result is that a single Newton-Raphson iteration of the algorithm costs between 1.5 and 2 times that of an elastic calculation. Examples alsomore » illustrate the successful convergence of the algorithm in complicated situations. For example, without using the new contributions presented here, the algorithm fails to converge for approximately 50% of the trial stresses for a common geomechanical model of sedementary rocks, while the current algorithm results in complete success. Since it involves no approximations, the algorithm is used to quantify the accuracy of an efficient, pragmatic, but approximate, algorithm used for sedimentary-rock plasticity in a commercial software package. Furthermore, the main weakness of the algorithm is identified as the difficulty of correctly choosing the set of initially active constraints in the general setting.« less

Steady and transient fluid shear stress stimulate NO release in osteoblasts through distinct biochemical pathways

NASA Technical Reports Server (NTRS)

McAllister, T. N.; Frangos, J. A.

1999-01-01

Fluid flow has been shown to be a potent stimulus in osteoblasts and osteocytes and may therefore play an important role in load-induced bone remodeling. The objective of this study was to investigate the characteristics of flow-activated pathways. Previously we reported that fluid flow stimulates rapid and continuous release of nitric oxide (NO) in primary rat calvarial osteoblasts. Here we demonstrate that flow-induced NO release is mediated by shear stress and that this response is distinctly biphasic. Transients in shear stress associated with the onset of flow stimulated a burst in NO production (8.2 nmol/mg of protein/h), while steady flow stimulated sustained NO production (2.2 nmol/mg of protein/h). Both G-protein inhibition and calcium chelation abolished the burst phase but had no effect on sustained production. Activation of G-proteins stimulated dose-dependent NO release in static cultures of both calvarial osteoblasts and UMR-106 osteoblast-like cells. Pertussis toxin had no effect on NO release. Calcium ionophore stimulated low levels of NO production within 15 minutes but had no effect on sustained production. Taken together, these data suggest that fluid shear stress stimulates NO release by two distinct pathways: a G-protein and calcium-dependent phase sensitive to flow transients, and a G-protein and calcium-independent pathway stimulated by sustained flow.

How to expand irrigated land in a sustainable way ?

NASA Astrophysics Data System (ADS)

Pastor, Amandine V.; Ludwig, Fulco; Palazzo, Amanda; Havlik, Petr; Kabat, Pavel

2015-04-01

Allocation of agriculture commodities and water resources is subject to changes due to climate change, population increase and changes in dietary patterns. This study focused on including global water availability including environmental flow requirements with water withdrawal from irrigation and other sectors (industry, household and hydropower) at a monthly time-step in the GLOBIOM model. This model allows re-adjustment of land-use allocation, crop management, consumption and international trade. The GLOBIOM model induces an endogenous change in water price depending on water supply and demand. In this study, the focus was on how the inclusion of water resources affects land-use and, in particular, how global change will influence repartition of irrigated and rainfed lands at global scale. We used the climate change scenario including a radiative forcing of 2.6 W/m2 (RCP2.6), the socio-economic scenario (SSP2: middle-of-road), and the environmental flow method based on monthly flow allocation (the Variable Monthly Flow method) with high and low restrictions. Irrigation withdrawals were adjusted to a monthly time-step to account for biophysical water limitations at finer time resolution. Our results show that irrigated land might decrease up to 37% on average depending on the choice of EFR restrictions. Several areas were identified as future hot-spots of water stress such as the Mediterranean and Middle-East regions and parts of South-East Asia where the Water Stress Indicator (WSI) ranges from 0.4 to 1 by 2050. Other countries were identified to be in safe position in terms of water stress such as North-European countries. Some countries such as India expect a significant increase in water demand which might be compensated by an increase in water supply with climate change scenario. Re-allocation of rainfed and irrigated land might be useful information for land-use planners and water managers at an international level to decide on appropriate legislations on climate change mitigation/adaptation when exposure and sensitivity to climate change is high and/or on adaptation measures to face increasing water demand. For example, some countries are likely to adopt measures to increase their water use efficiencies (irrigation system, soil and water conservation practices) to face water shortages, while others might consider improving their trade policy to avoid food shortage.

Investigation of blood flow rheology using second-grade viscoelastic model (Phan-Thien-Tanner) within carotid artery.

PubMed

Ramiar, Abas; Larimi, Morsal Momenti; Ranjbar, Ali Akbar

2017-01-01

Hemodynamic factors, such as Wall Shear Stress (WSS), play a substantial role in arterial diseases. In the larger arteries, such as the carotid artery, interaction between the vessel wall and blood flow affects the distribution of hemodynamic factors. The fluid is considered to be non-Newtonian, whose flow is governed by the equation of a second-grade viscoelastic fluid and the effects of viscoelastic on blood flow in carotid artery is investigated. Pulsatile flow studies were carried out in a 3D model of carotid artery. The governing equations were solved using finite volume C++ based on open source code, OpenFOAM. To describe blood flow, conservation of mass and momentum, a constitutive relation of simplified Phan-Thien-Tanner (sPTT), and appropriate relations were used to explain shear thinning behavior. The first recirculation was observed at t = 0.2 s, in deceleration phase. In the acceleration phase from t = 0.3 s to t = 0.5 s, vortex and recirculation sizes in bulb regions in both ECA and ICA gradually increased. As is observed in the line graphs based on extracted data from ICA, at t = 0.2 s, τyy is the maximum amount of wall shear stress and τxy the minimum one. The maximum shear stress occurred in the inner side of the main branch (inner side of ICA and ECA) because the velocity of blood flow in the inner side of the bulb region was maximum due to the created recirculation zone in the opposite side in this area. The rheology of blood flow and shear stress in various important parts (the area that are in higher rates of WSS such as bifurcation region and the regions after bulb areas in both branches, Line1-4 in Fig. 7) were also analyzed. The investigation of velocity stream line, velocity profile and shear stress in various sections of carotid artery showed that the maximum shear stress occurred in acceleration phase and in the bifurcation region between ECA and ICA which is due to velocity gradients and changes in thinning behavior of blood and increasing strain rate in Newtonian stress part.

Couple stress fluid flow in a rotating channel with peristalsis

NASA Astrophysics Data System (ADS)

Abd elmaboud, Y.; Abdelsalam, Sara I.; Mekheimer, Kh. S.

2018-04-01

This article describes a new model for obtaining closed-form semi-analytical solutions of peristaltic flow induced by sinusoidal wave trains propagating with constant speed on the walls of a two-dimensional rotating infinite channel. The channel rotates with a constant angular speed about the z - axis and is filled with couple stress fluid. The governing equations of the channel deformation and the flow rate inside the channel are derived using the lubrication theory approach. The resulting equations are solved, using the homotopy perturbation method (HPM), for exact solutions to the longitudinal velocity distribution, pressure gradient, flow rate due to secondary velocity, and pressure rise per wavelength. The effect of various values of physical parameters, such as, Taylor's number and couple stress parameter, together with some interesting features of peristaltic flow are discussed through graphs. The trapping phenomenon is investigated for different values of parameters under consideration. It is shown that Taylor's number and the couple stress parameter have an increasing effect on the longitudinal velocity distribution till half of the channel, on the flow rate due to secondary velocity, and on the number of closed streamlines circulating the bolus.

Parallel-plate Flow Chamber and Continuous Flow Circuit to Evaluate Endothelial Progenitor Cells under Laminar Flow Shear Stress

PubMed Central

Lane, Whitney O.; Jantzen, Alexandra E.; Carlon, Tim A.; Jamiolkowski, Ryan M.; Grenet, Justin E.; Ley, Melissa M.; Haseltine, Justin M.; Galinat, Lauren J.; Lin, Fu-Hsiung; Allen, Jason D.; Truskey, George A.; Achneck, Hardean E.

2012-01-01

The overall goal of this method is to describe a technique to subject adherent cells to laminar flow conditions and evaluate their response to well quantifiable fluid shear stresses1. Our flow chamber design and flow circuit (Fig. 1) contains a transparent viewing region that enables testing of cell adhesion and imaging of cell morphology immediately before flow (Fig. 11A, B), at various time points during flow (Fig. 11C), and after flow (Fig. 11D). These experiments are illustrated with human umbilical cord blood-derived endothelial progenitor cells (EPCs) and porcine EPCs2,3. This method is also applicable to other adherent cell types, e.g. smooth muscle cells (SMCs) or fibroblasts. The chamber and all parts of the circuit are easily sterilized with steam autoclaving. In contrast to other chambers, e.g. microfluidic chambers, large numbers of cells (> 1 million depending on cell size) can be recovered after the flow experiment under sterile conditions for cell culture or other experiments, e.g. DNA or RNA extraction, or immunohistochemistry (Fig. 11E), or scanning electron microscopy5. The shear stress can be adjusted by varying the flow rate of the perfusate, the fluid viscosity, or the channel height and width. The latter can reduce fluid volume or cell needs while ensuring that one-dimensional flow is maintained. It is not necessary to measure chamber height between experiments, since the chamber height does not depend on the use of gaskets, which greatly increases the ease of multiple experiments. Furthermore, the circuit design easily enables the collection of perfusate samples for analysis and/or quantification of metabolites secreted by cells under fluid shear stress exposure, e.g. nitric oxide (Fig. 12)6. PMID:22297325

Preferential paths in yield stress fluid flow through a porous medium

NASA Astrophysics Data System (ADS)

Guasto, Jeffrey; Waisbord, Nicolas; Stoop, Norbert; Dunkel, Jörn

2016-11-01

A broad range of biological, geological, and industrial materials with complex rheological properties are subjected to flow through porous media in applications ranging from oil recovery to food manufacturing. In this experimental study, we examine the flow of a model yield stress fluid (Carbopol micro-gel) through a quasi-2D porous medium, fabricated in a microfluidic channel. The flow is driven by applying a precisely-controlled pressure gradient and measured by particle tracking velocimetry, and our observations are complemented by a pore-network model of the yield stress fluid flow. While remaining unyielded at small applied pressure, the micro-gel begins to yield at a critical pressure gradient, exhibiting a single preferential flow path that percolates through the porous medium. As the applied pressure gradient increases, we observe a subsequent coarsening and invasion of the yielded, fluidized network. An examination of both the yielded network topology and pore-scale flow reveal that two cooperative phenomena are involved in sculpting the preferential flow paths: (1) the geometry of the porous microstructure, and (2) the adhesive surface interactions between the micro-gel and substrate. NSF CBET-1511340.

On the connection between Maximum Drag Reduction and Newtonian fluid flow

NASA Astrophysics Data System (ADS)

Whalley, Richard; Park, Jae-Sung; Kushwaha, Anubhav; Dennis, David; Graham, Michael; Poole, Robert

2014-11-01

To date, the most successful turbulence control technique is the dissolution of certain rheology-modifying additives in liquid flows, which results in a universal maximum drag reduction (MDR) asymptote. The MDR asymptote is a well-known phenomenon in the turbulent flow of complex fluids; yet recent direct numerical simulations of Newtonian fluid flow have identified time intervals showing key features of MDR. These intervals have been termed ``hibernating turbulence'' and are a weak turbulence state which is characterised by low wall-shear stress and weak vortical flow structures. Here, in this experimental investigation, we monitor the instantaneous wall-shear stress in a fully-developed turbulent channel flow of a Newtonian fluid with a hot-film probe whilst simultaneously measuring the streamwise velocity at various distances above the wall with laser Doppler velocimetry. We show, by conditionally sampling the streamwise velocity during low wall-shear stress events, that the MDR velocity profile is approached in an additive-free, Newtonian fluid flow. This result corroborates recent numerical investigations, which suggest that the MDR asymptote in polymer solutions is closely connected to weak, transient Newtonian flow structures.

Reynolds-Stress and Triple-Product Models Applied to Flows with Rotation and Curvature

NASA Technical Reports Server (NTRS)

Olsen, Michael E.

2016-01-01

Predictions for Reynolds-stress and triple product turbulence models are compared for flows with significant rotational effects. Driver spinning cylinder flowfield and Zaets rotating pipe case are to be investigated at a minimum.

Influence of neighboring adherent cells on laminar flow induced shear stress in vitro—A systematic study

PubMed Central

Djukelic, Mario; Westerhausen, Christoph

2017-01-01

Cells experience forces if subjected to laminar flow. These forces, mostly of shear force character, are strongly dependent not only on the applied flow field itself but also on hydrodynamic effects originating from neighboring cells. This particularly becomes important for the interpretation of data from in vitro experiments in flow chambers without confluent cell layers. By employing numerical Finite Element Method simulations of such assemblies of deformable objects under shear flow, we investigate the occurring stress within elastic adherent cells and the influence of neighboring cells on these quantities. For this, we simulate single and multiple adherent cells of different shapes fixed on a solid substrate under laminar flow parallel to the substrate for different velocities. We determine the local stress within the cells close to the cell-substrate-interface and the overall stress of the cells by surface integration over the cell surface. Comparing each measurand in the case of a multiple cell situation with the corresponding one of single cells under identical conditions, we introduce a dimensionless influence factor. The systematic variation of the distance and angle between cells, where the latter is with respect to the flow direction, flow velocity, Young's modulus, cell shape, and cell number, enables us to describe the actual influence on a cell. Overall, we here demonstrate that the cell density is a crucial parameter for all studies on flow induced experiments on adherent cells in vitro. PMID:28798851

A laboratory study of mean flow generation in rotating fluids by Reynolds stress gradients

NASA Astrophysics Data System (ADS)

McGuinness, D. S.; Boyer, D. L.; Fernando, H. J. S.

2001-06-01

Laboratory experiments were conducted that demonstrate that a mean azimuthal flow can be produced by introducing Reynolds stress gradients to a rotating fluid with zero initial mean flow. This mechanism may play a role in the generation of mean currents in coastal regions. The experiments entail the establishment of turbulence in a thin annular-shaped region centered within a cylindrical test cell through the use of a vertically oscillating grid. This region rests in a horizontal plane perpendicular to the vertical axis of the tank, and the entire system is placed on a turntable to simulate background rotation. Flow visualization techniques are used to depict qualitative features of the resulting flow field. Measurements of the mean and turbulent velocity fields are performed using a two-component laser-Doppler velocimeter. The results show how rectified currents (mean flows) can be generated via Reynolds stress gradients induced by periodic forcing of the grid. In the absence of background rotation, rectified flow is observed in the radial and vertical directions only. The presence of background rotation tends to organize these motions in that the flow tends to move parallel to the turbulent source, i.e., in the azimuthal direction, with the source (strong turbulence) located to the right, facing downstream. The influence of rotation on the Reynolds stresses and their gradients as well as on the ensuing mean flow is evaluated, and the observations are examined by considering individual contributions of the terms in the Reynolds-averaged momentum equations.

The possible role of Reynolds stress in the creation of a transport barrier in tokamak edge plasmas

NASA Astrophysics Data System (ADS)

Vergote, M.; van Schoor, M.; Xu, Y.; Jachmich, S.; Weynants, R.; Hron, M.; Stöckel, J.

2005-03-01

To obtain a good confinement, mandatory in a fusion reactor, the understanding of the formation of transport barriers in the edge plasma of a tokamak is essential. Turbulence, the major candidate to explain anomalous transport, can be quenched by sheared flows in the edge which rip the convective cells apart, thus forming a barrier. Experimental evidence from the Chinese HT-6M tokamak [Y.H. Xu et al.: Phys. Rev. Lett. 84 (2000) 3867], points to the fact that momentum transfer from the turbulence can create these sheared flows via the Reynolds stresses. A new 1-D fluid model for the generation of the poloidal flow, has been developed taking into account the driving force of the Reynolds stress and the friction forces due to neutrals and parallel viscosity. Special attention has been dedicated to the computation of the flux-surface-averaging for the various terms. This model has been confronted with the experimental results obtained in the HT-6M tokamak, where Reynolds stresses were generated by application of a turbulent heating pulse. If the model is applied in cylindrical geometry, the calculated Reynolds stress-induced flow agrees well with the measured poloidal velocity in the plasma edge. However, when the full toroidal geometry is taken into account, it seems that the Reynolds stresses are too small to explain the observed rotation. This indicates that the role of the Reynolds stresses in inducing macroscopic flow in the torus is weakened. A combined system of probes allowing to measure the Reynolds stress and the rotation velocity simultaneously, has been developed and installed on the CASTOR tokamak (Prague). We report here on the first results obtained.

Slope instability in complex 3D topography promoted by convergent 3D groundwater flow

NASA Astrophysics Data System (ADS)

Reid, M. E.; Brien, D. L.

2012-12-01

Slope instability in complex topography is generally controlled by the interaction between gravitationally induced stresses, 3D strengths, and 3D pore-fluid pressure fields produced by flowing groundwater. As an example of this complexity, coastal bluffs sculpted by landsliding commonly exhibit a progression of undulating headlands and re-entrants. In this landscape, stresses differ between headlands and re-entrants and 3D groundwater flow varies from vertical rainfall infiltration to lateral groundwater flow on lower permeability layers with subsequent discharge at the curved bluff faces. In plan view, groundwater flow converges in the re-entrant regions. To investigate relative slope instability induced by undulating topography, we couple the USGS 3D limit-equilibrium slope-stability model, SCOOPS, with the USGS 3D groundwater flow model, MODFLOW. By rapidly analyzing the stability of millions of potential failures, the SCOOPS model can determine relative slope stability throughout the 3D domain underlying a digital elevation model (DEM), and it can utilize both fully 3D distributions of pore-water pressure and material strength. The two models are linked by first computing a groundwater-flow field in MODFLOW, and then computing stability in SCOOPS using the pore-pressure field derived from groundwater flow. Using these two models, our analyses of 60m high coastal bluffs in Seattle, Washington showed augmented instability in topographic re-entrants given recharge from a rainy season. Here, increased recharge led to elevated perched water tables with enhanced effects in the re-entrants owing to convergence of groundwater flow. Stability in these areas was reduced about 80% compared to equivalent dry conditions. To further isolate these effects, we examined groundwater flow and stability in hypothetical landscapes composed of uniform and equally spaced, oscillating headlands and re-entrants with differing amplitudes. The landscapes had a constant slope for both headlands and re-entrants to minimize slope effects on stability. Despite these equal slopes, our analyses, given dry conditions, illustrated that the headlands can be 5-7% less stable than the re-entrants, owing to the geometry of the 3D failure mass with the lowest stability. We then simulated groundwater flow in these landscapes; flow was caused by recharge perching on a horizontal low permeability layer with discharge at the bluff faces. By systematically varying recharge, hydraulic conductivity of the material, and conductance at the bluffs, we created different 3D pore-pressure fields. Recharge rates and hydraulic conductivities controlled the height of the water table, whereas bluff conductance influenced the gradient of the water table near the bluff face. Given elevated water tables with steep gradients, bluffs in the re-entrants became unstable where flow converged. Thus, with progressively stronger effects from water flow, overall instability evolved from relatively unstable headlands to more uniform stability to relatively unstable re-entrants. Larger re-entrants led to more 3D flow convergence and greater localized instability. One- or two-dimensional models cannot fully characterize slope instability in complex topography.

Computational Modeling of Blood Flow in the TrapEase Inferior Vena Cava Filter

DOE Office of Scientific and Technical Information (OSTI.GOV)

Singer, M A; Henshaw, W D; Wang, S L

To evaluate the flow hemodynamics of the TrapEase vena cava filter using three dimensional computational fluid dynamics, including simulated thrombi of multiple shapes, sizes, and trapping positions. The study was performed to identify potential areas of recirculation and stagnation and areas in which trapped thrombi may influence intrafilter thrombosis. Computer models of the TrapEase filter, thrombi (volumes ranging from 0.25mL to 2mL, 3 different shapes), and a 23mm diameter cava were constructed. The hemodynamics of steady-state flow at Reynolds number 600 was examined for the unoccluded and partially occluded filter. Axial velocity contours and wall shear stresses were computed. Flowmore » in the unoccluded TrapEase filter experienced minimal disruption, except near the superior and inferior tips where low velocity flow was observed. For spherical thrombi in the superior trapping position, stagnant and recirculating flow was observed downstream of the thrombus; the volume of stagnant flow and the peak wall shear stress increased monotonically with thrombus volume. For inferiorly trapped spherical thrombi, marked disruption to the flow was observed along the cava wall ipsilateral to the thrombus and in the interior of the filter. Spherically shaped thrombus produced a lower peak wall shear stress than conically shaped thrombus and a larger peak stress than ellipsoidal thrombus. We have designed and constructed a computer model of the flow hemodynamics of the TrapEase IVC filter with varying shapes, sizes, and positions of thrombi. The computer model offers several advantages over in vitro techniques including: improved resolution, ease of evaluating different thrombus sizes and shapes, and easy adaptation for new filter designs and flow parameters. Results from the model also support a previously reported finding from photochromic experiments that suggest the inferior trapping position of the TrapEase IVC filter leads to an intra-filter region of recirculating/stagnant flow with very low shear stress that may be thrombogenic.« less

A study of the second and third order closure models of turbulence for prediction of separated shear flows

NASA Technical Reports Server (NTRS)

Amano, R. S.

1985-01-01

The hybrid model of the Reynolds-stress turbulence closure is tested for the computation of the flows over a step and disk. Here it is attempted to improve the redistributive action of the turbulence energy among the Reynolds stresses. By evaluating the existing models for the pressure-strain correlation, better coefficients are obtained for the prediction of separating shear flows. Furthermore, the diffusion rate of the Reynolds stresses is reevaluated adopting several algebraic correlations for the triple-velocity products. The models of Cormack et al., Daly-Harlow, Hanjalic-Launder, and Shir were tested for the reattaching shear flows. It was generally observed that all these algebraic models give considerably low values of the triple-velocity products. This is attributed to the fact that none of the algebraic models can take the convective effect of the triple-velocity products into account in the separating shear flows, thus resulting in much lower diffusion rate than Reynolds stresses. In order to improve the evaluation of these quantities correction factors are introduced based on the comparison with some experimental data.

Characterization of the hydrogeology and stress state in the vicinity of the homestake mine, Lead, SD

NASA Astrophysics Data System (ADS)

Ebenhack, Johnathan Foss

Underground workings in fractured rock are common worldwide. They have applications in numerous areas and fields of study. These include mining operations, civil engineering projects like tunnels and underground facilities, and research projects that require underground laboratories such as the physics research being conducted by Sanford Laboratory at the former Homestake mine and Fermi Laboratory near Chicago (Bahcall et al. 2001, Elsworth 2009, Sadoulet et al. 2006, bge science DUSEL, fnal.gov). These excavations can reach several kilometers in depth including the 3.9 km deep TauTona mine in South Africa, the 3 km deep LaRonde mine in Quebec and the 2.4 km deep Homestake mine in South Dakota. Large quantities of rock are removed when constructing deep excavations, for example Rahn and Roggenthen (2002) estimated the total volume of rock removed from the Homestake mine to be 2.1x107 m3. Removing large volumes of rock alters the local stress state and ground water flow, potentially increasing risks to workers and the environment (Kaiser et al. 2008, Blodgett et al. 2002, Lucier et al. 2009, Goldbach 2010, Kang et al. 2010). The objective of this research is to develop a better understanding of how deep rock excavations can alter groundwater flow, stress state, and deformation in the rock that envelopes them. The approach is to evaluate how the hydraulic head, flow paths and stress state have been affected by excavation at the Homestake mine in Lead, South Dakota, one of the deepest mines in North America. The Homestake mine was selected as a focus of this research because it has recently been evaluated as the site of a deep underground research laboratory where an understanding of the groundwater flow and stress state was needed to plan underground experiments. The investigation includes poroelastic modeling of the Homestake mine using available geologic and geophysical data and mine records. Results from the analyses indicate that mining and dewatering have changed the hydrology and stress state in the vicinity of the Homestake mine. Dewatering reduces the hydraulic head and changes the flow systems in the vicinity of the mine. Four major hydrogeologic zones are recognized: 1.) a Shallow Flow System in the upper few hundred meters that dominates recharge and discharge to streams, 2.) a Recharge Capture Zone where water that has entered the region as recharge since mining began is captured by the mine, 3.) a Storage Capture Zone where water from storage in the host rock around the mine is captured, and 4.) a Mine Workings Zone where rock has been removed. Water enters the system at the top of the Shallow Flow System and either discharges to the streams or flows downward and becomes recharge to the lower capture zones. The Recharge Capture Zone grows with time as regions of storage are depleted and new recharge enters, and eventually it is assumed that the entire capture zone for the mine will become the Recharge Capture Zone. Fluxes from the Shallow Flow System to the Recharge Capture Zone typically range from 1x10-9 to 4x10-9 m/s. The largest recharge fluxes from the Shallow Flow System to the Recharge Capture Zone occur above the shallowest portions of the mine. Recharge flux also occurs above areas adjacent to the mine, and when projected to the surface the Recharge Capture Zone creates a roughly elliptical shape that is 6 km x 3.6 km. The Storage Capture Zone extends out beyond and below the Recharge Capture Zone and when projected to the surface creates a roughly elliptical region that is approximately 8.3 km x 6.6 km and extends down to depths of almost 5 km. Hydraulic heads and flow paths have been affected beyond the Storage Capture Zone but this water had not reached the mine by 135 years and therefore these regions are not included in the capture zones. The model was calibrated using in-situ stress data at various points in the mine to improve its ability to estimate the stress state and mechanical deformation around the Homestake mine. This was done by varying the rock density, Poisson's ratio, the effective Young's modulus of the workings region, and including initial stresses until predicted stresses best fit in-situ stress data. The changing mechanical properties in the workings and dewatering cause changes to the stress around the mine. The mining process typically causes increased compression laterally around the workings and decreased compression above, below, and within the workings. The greatest changes in total stress are near the base of the mine and reach roughly 40 MPa between the ore bodies and in the lower portions of the West Ore Body. The softening of the mine region because of material removal and decreased fluid pressure in the workings results in deformation in the vicinity of the mine. Subsidence occurs above the mine region and is greatest near the surface and decreases with depth; above the shallowest workings subsidence can reach approximately 0.18 m. There is also uplift along the footwall of the workings in the deeper portions of the mine that can reach up to 0.022 m. Horizontal displacements of as much as several centimeters occur around the mine and with displacement towards the workings region. Deformation in the vicinity of the mine results in tilt that is towards the workings with the greatest tilts near the surface. A fault that intersects the West Ore Body was considered as a location for an experiment into the mechanics of earthquake nucleation, so the stress state in the vicinity of this feature was of particular interest. This simulation shows that mining and dewatering reduce fluid pressure and change stresses along the fault. The shear stress along the fault typically increases along most of the fault and decreases in the region where the fault and West Ore Body intersect. Increased shear is typically on the order of 1 to 2 MPa but can reach as much as 5 MPa in areas around the intersection of the fault and West Ore Body. In the region along the fault intersecting the West Ore Body, the decrease in shear can reach -11 MPa. The total normal stress along the fault becomes more compressive along most of the fault and less compressive in the intersection between the fault and West Ore Body. The increase in total compression is approximately 2 MPa, and the reduction in compression in the intersection is approximately 10 MPa. The critical shear stress along the fault was calculated using Mohr-Coulomb failure criteria presented by Byerlee (1978), and the ratio of the estimated shear stress along the fault and the critical shear stress (ts/tf) was found to approximate the potential for slip along the fault. Mining results in a reduction in slip potential with values of ts/t f ranging from 0.66 to 1.1 before mining and from 0.22 to 0.67 after mining. This reduction in slip potential results from reductions in fluid pressure and increased normal compression caused by mining activities.

Reynolds Stress and Sheared Poloidal Flow in the Edge Plasma Region of the HT-6M Tokamak

NASA Astrophysics Data System (ADS)

Wang, Wen-Hao; Yu, Chang-Xuan; Xu, Yu-Hong; Ling, Bi-Li; Gong, Xian-Zu; Liu, Bao-Hua; Wan, Bao-Nian

2001-02-01

High spatial resolution measurements of the electrostatic Reynolds stress, radial electric field and poloidal phase velocity of fluctuations in the edge region of the HT-6M tokamak are carried out. The Reynolds stress shows a radial gradient in proximity to the poloidal velocity shear. A comparison of the profiles between the Reynolds stress gradient and the poloidal velocity damping reveals some similarity in their magnitude and radial structure. These facts suggest that the turbulence-induced Reynolds stress may play a significant role in generating the poloidal flow in the plasma edge region.

A film-based wall shear stress sensor for wall-bounded turbulent flows

NASA Astrophysics Data System (ADS)

Amili, Omid; Soria, Julio

2011-07-01

In wall-bounded turbulent flows, determination of wall shear stress is an important task. The main objective of the present work is to develop a sensor which is capable of measuring surface shear stress over an extended region applicable to wall-bounded turbulent flows. This sensor, as a direct method for measuring wall shear stress, consists of mounting a thin flexible film on the solid surface. The sensor is made of a homogeneous, isotropic, and incompressible material. The geometry and mechanical properties of the film are measured, and particles with the nominal size of 11 μm in diameter are embedded on the film's surface to act as markers. An optical technique is used to measure the film deformation caused by the flow. The film has typically deflection of less than 2% of the material thickness under maximum loading. The sensor sensitivity can be adjusted by changing the thickness of the layer or the shear modulus of the film's material. The paper reports the sensor fabrication, static and dynamic calibration procedure, and its application to a fully developed turbulent channel flow at Reynolds numbers in the range of 90,000-130,000 based on the bulk velocity and channel full height. The results are compared to alternative wall shear stress measurement methods.

Flow of “stress power-law” fluids between parallel rotating discs with distinct axes

DOE PAGES

Srinivasan, Shriram; Karra, Satish

2015-04-16

The problem of flow between parallel rotating discs with distinct axes corresponds to the case of flow in an orthogonal rheometer and has been studied extensively for different fluids since the instrument's inception. All the prior studies presume a constitutive prescription of the fluid stress in terms of the kinematical variables. In this paper, we approach the problem from a different perspective, i.e., a constitutive specification of the symmetric part of the velocity gradient in terms of the Cauchy stress. Such an approach ensures that the boundary conditions can be incorporated in a manner quite faithful to real world experimentsmore » with the instrument. Interestingly, the choice of the boundary condition is critical to the solvability of the problem for the case of creeping/Stokes flow. Furthermore, when the no-slip condition is enforced at the boundaries, depending on the model parameters and axes offset, the fluid response can show non-uniqueness or unsolvability, features which are absent in a conventional constitutive specification. In case of creeping/Stokes flow with prescribed values of the stress, the fluid response is indeterminate. We also record the response of a particular case of the given “stress power-law” fluid; one that cannot be attained by the conventional power-law fluids.« less

Heat transfer, velocity-temperature correlation, and turbulent shear stress from Navier-Stokes computations of shock wave/turbulent boundary layer interaction flows

NASA Technical Reports Server (NTRS)

Wang, C. R.; Hingst, W. R.; Porro, A. R.

1991-01-01

The properties of 2-D shock wave/turbulent boundary layer interaction flows were calculated by using a compressible turbulent Navier-Stokes numerical computational code. Interaction flows caused by oblique shock wave impingement on the turbulent boundary layer flow were considered. The oblique shock waves were induced with shock generators at angles of attack less than 10 degs in supersonic flows. The surface temperatures were kept at near-adiabatic (ratio of wall static temperature to free stream total temperature) and cold wall (ratio of wall static temperature to free stream total temperature) conditions. The computational results were studied for the surface heat transfer, velocity temperature correlation, and turbulent shear stress in the interaction flow fields. Comparisons of the computational results with existing measurements indicated that (1) the surface heat transfer rates and surface pressures could be correlated with Holden's relationship, (2) the mean flow streamwise velocity components and static temperatures could be correlated with Crocco's relationship if flow separation did not occur, and (3) the Baldwin-Lomax turbulence model should be modified for turbulent shear stress computations in the interaction flows.

Disturbed flow mediated modulation of shear forces on endothelial plane: A proposed model for studying endothelium around atherosclerotic plaques

NASA Astrophysics Data System (ADS)

Balaguru, Uma Maheswari; Sundaresan, Lakshmikirupa; Manivannan, Jeganathan; Majunathan, Reji; Mani, Krishnapriya; Swaminathan, Akila; Venkatesan, Saravanakumar; Kasiviswanathan, Dharanibalan; Chatterjee, Suvro

2016-06-01

Disturbed fluid flow or modulated shear stress is associated with vascular conditions such as atherosclerosis, thrombosis, and aneurysm. In vitro simulation of the fluid flow around the plaque micro-environment remains a challenging approach. Currently available models have limitations such as complications in protocols, high cost, incompetence of co-culture and not being suitable for massive expression studies. Hence, the present study aimed to develop a simple, versatile model based on Computational Fluid Dynamics (CFD) simulation. Current observations of CFD have shown the regions of modulated shear stress by the disturbed fluid flow. To execute and validate the model in real sense, cell morphology, cytoskeletal arrangement, cell death, reactive oxygen species (ROS) profile, nitric oxide production and disturbed flow markers under the above condition were assessed. Endothelium at disturbed flow region which had been exposed to low shear stress and swirling flow pattern showed morphological and expression similarities with the pathological disturbed flow environment reported previously. Altogether, the proposed model can serve as a platform to simulate the real time micro-environment of disturbed flow associated with eccentric plaque shapes and the possibilities of studying its downstream events.

Viscous pressure correction in the irrotational flow outside Prandtl's boundary layer

NASA Astrophysics Data System (ADS)

Joseph, Daniel; Wang, Jing

2004-11-01

We argue that boundary layers on solid with irrotational motion outside are like a gas bubble because the shear stress vanishes at the edge of the boundary layer but the irrotational shear stress does not. This discrepancy induces a pressure correction and an additional drag which can be advertised as due to the viscous dissipation of the irrotational flow. Typically, this extra correction to the drag would be relatively small. A much more interesting implication of the extra pressure theory arises from the consideration of the effects of viscosity on the normal stress on a solid boundary which are entirely neglected in Prandtl's theory. It is very well known and easily demonstrated that as a consequence of the continuity equation the viscous normal stress must vanish on a rigid solid. It follows that all the greatly important effects of viscosity on the normal stress are buried in the pressure and the leading order effects of viscosity on the normal stress can be obtained from the viscous correction of viscous potential flow.

Information Needs While A Disaster Is Occurring

NASA Astrophysics Data System (ADS)

Perry, S. C.

2010-12-01

Evidence from recent earthquakes, wildfires, and debris flows in southern California indicates that many people - local officials as well as residents and visitors - lack important understanding during the time that a disaster is unfolding, a time of uncertainty and confusion. While some of the uncertainty is inherent, some could be alleviated. Physical scientists and engineers know what to expect as the event unfolds. Social scientists know how humans will react during a disaster, and how to effectively communicate the warnings or evacuation orders that may precede it. Such knowledge can improve public safety. As just a few of many examples: - Based on questions posed at numerous public talks, many individuals who practice "Drop Cover and Hold" during earthquake drills do not understand what they are protecting themselves against, and thus cannot determine what to do when an earthquake strikes and they have no cover available. Similarly, they do not know how to act during the aftershocks that follow. - The 2009 Station Fire in the San Gabriel Mountains put foothills communities at risk, first from the wildfire and then from debris flows. Some neighborhoods received multiple evacuation notices during a few days or months. Local officials have expressed frustration and concern about an evacuation compliance rate that is steadily dropping and is now below 50%. The debris flow danger will persist over the next 2-4 winters yet evacuation compliance may drop lower still. - On February 6, 2010, a significant rainstorm brought the threat of imminent debris flows to areas burned by the Station Fire. In one neighborhood, residents loaded their cars with important belongings then waited for indications that they should evacuate. Powerful debris flows suddenly appeared, sweeping the cars downhill and destroying both cars and belongings. Some residents did understand that rainfall intensity would control the generation of debris flows in that storm. But they didn't understand that rainfall intensity at their homes might be less than the intensity up in the mountains where the debris flows would start. Nor did they know that debris flows travel too quickly to be outrun. These and many other examples indicate need for social and natural scientists to increase awareness of what to expect when the disaster strikes. This information must be solidly understood before the event occurs - while a disaster is unfolding there are no teachable moments. Case studies indicate that even those who come into a disaster well educated about the phenomenon can struggle to apply what they know when the real situation is at hand. In addition, psychological studies confirm diminished ability to comprehend information at times of stress.

Multi-cellular 3D human primary liver cell culture elevates metabolic activity under fluidic flow.

PubMed

Esch, Mandy B; Prot, Jean-Matthieu; Wang, Ying I; Miller, Paula; Llamas-Vidales, Jose Ricardo; Naughton, Brian A; Applegate, Dawn R; Shuler, Michael L

2015-05-21

We have developed a low-cost liver cell culture device that creates fluidic flow over a 3D primary liver cell culture that consists of multiple liver cell types, including hepatocytes and non-parenchymal cells (fibroblasts, stellate cells, and Kupffer cells). We tested the performance of the cell culture under fluidic flow for 14 days, finding that hepatocytes produced albumin and urea at elevated levels compared to static cultures. Hepatocytes also responded with induction of P450 (CYP1A1 and CYP3A4) enzyme activity when challenged with P450 inducers, although we did not find significant differences between static and fluidic cultures. Non-parenchymal cells were similarly responsive, producing interleukin 8 (IL-8) when challenged with 10 μM bacterial lipoprotein (LPS). To create the fluidic flow in an inexpensive manner, we used a rocking platform that tilts the cell culture devices at angles between ±12°, resulting in a periodically changing hydrostatic pressure drop between reservoirs and the accompanying periodically changing fluidic flow (average flow rate of 650 μL min(-1), and a maximum shear stress of 0.64 dyne cm(-2)). The increase in metabolic activity is consistent with the hypothesis that, similar to unidirectional fluidic flow, primary liver cell cultures increase their metabolic activity in response to fluidic flow periodically changes direction. Since fluidic flow that changes direction periodically drastically changes the behavior of other cells types that are shear sensitive, our findings support the theory that the increase in hepatic metabolic activity associated with fluidic flow is either activated by mechanisms other than shear sensing (for example increased opportunities for gas and metabolite exchange), or that it follows a shear sensing mechanism that does not depend on the direction of shear. Our mode of device operation allows us to evaluate drugs under fluidic cell culture conditions and at low device manufacturing and operation costs.

MMS observation of energy conversion and collisionless plasma dissipation channels in the turbulent magnetosheath

NASA Astrophysics Data System (ADS)

Parashar, T.; Yang, Y.; Chasapis, A.; Matthaeus, W. H.

2017-12-01

High resolution Magnetospheric Multiscale (MMS) plasma and magnetic field data obtained in the inhomogeneous turbulent magnetosheath directly reveals the exchanges of energy between electromagnetic, flow and random kinetic energy. The parameters that quantify these exchanges are based on standard manipulations of the collisionless Vlasov model of plasma dynamics [1], without appeal to viscous or other closures. No analysis of heat transport or heat conduction is carried out. Several intervals of burst mode data in the magnetosheath are considered. Time series of the work done by the electromagnetic field, and the pressure-stress interaction enable description of the pathways to dissipation in this low collisionality plasma. Using these examples we demonstrate that the pressure-stress interaction provides important information not readily revealed in other diagnostics concerning the physical processes that are observed. This method does not require any specific mechanism for its application such as reconnection or a selected mode, although with increased experience it will be useful in distinguishing among proposed possibilities. [1] Y. Yang et al, Phys. Plasmas 24, 072306 (2017); doi: 10.1063/1.4990421.

On extended analytic theory of 2D ballooning modes in tokamak plasmas

NASA Astrophysics Data System (ADS)

Abdoul, Peshwaz; Dickinson, David; Roach, Colin; Wilson, Howard

2016-10-01

We have extended the leading order ballooning theory which typically yields more unstable isolated mode (IM) that usually sit on the outboard mid-plane, to higher order where less unstable general mode (GM) sits at a different poloidal location. Our analytic theory has revealed that any poloidal shift of the mode with respect to the outboard mid-plane - arising from the effect of profile variations, for example - is always accompanied by an asymmetry of the radial eigenmode structure. Hence, GMs have radial asymmetry. Our theory can have important consequences, especially for calculations that invoke quasilinear theory to model intrinsic rotation arising from Reynolds stress. This is very important in ITER for which external torques are small. In such theories it is the radial asymmetry in the global GM mode which can generate a Reynolds stress that could in principle contribute to the poloidal flow during the low to high (L-H) mode transition in tokamaks. I am also an associate member at the York Plasma Institute, University of York and teaching at the Physics Department, University of Sulaimani, Kurdistan Region, Iraq.

A comparison of three algebraic stress closures for combustor flow calculations

NASA Technical Reports Server (NTRS)

Nikjooy, M.; So, R. M. C.; Hwang, B. C.

1985-01-01

A comparison is made of the performance of two locally nonequilibrium and one equilibrium algebraic stress closures in calculating combustor flows. Effects of four different pressure-strain models on these closure models are also analyzed. The results show that the pressure-strain models have a much greater influence on the calculated mean velocity and turbulence field than the algebraic stress closures, and that the best mean strain model for the pressure-strain terms is that proposed by Launder, Reece and Rodi (1975). However, the equilibrium algebraic stress closure with the Rotta return-to-isotropy model (1951) for the pressure-strain terms gives as good a correlation with measurements as when the Launder et al. mean strain model is included in the pressure-strain model. Finally, comparison of the calculations with the standard k-epsilon closure results show that the algebraic stress closures are better suited for simple turbulent flow calculations.

Colorimetric qualification of shear sensitive liquid crystal coatings

NASA Technical Reports Server (NTRS)

Muratore, Joseph J., Jr.

1993-01-01

The work that has been done to date on the Shear Sensitive Liquid Crystal Project demonstrated that cholesteric liquid crystal coatings respond to both the direction and magnitude of a shearing force. The response of the coating is to selectively scatter incident white light into a spectrum of colors. Discernible color changes at a fixed angle of observation and illumination are the result of an applied shear stress. The intention was to be able to convert these observable color patterns from a flow visualization technique into a quantitative tool. One of the earlier intentions was to be able to use liquid crystals in dynamic flow fields. This was assumed possible because liquid crystals had made it possible to visualize transients in surface shear forces. Although the transients were visualized by color changes to an order one micro second, the time response of a coating to align to a shearing force is dependent on the magnitude of the change between its initial and final states. Unfortunately, the response is not instantaneous. It is for this reason any future attempt at quantifying the magnitude and directions of a shearing force are limited to surface shear stress vector fields in three dimensional steady state flows. This limitation does not significantly detract from the utility of liquid crystal coatings. The measurement of skin friction in the study of transition on wings, prediction of drag forces, performance assessment, and the investigation of boundary layer behavior is of great importance in aerodynamics. There exist numerous examples of techniques for the measurement of surface shear stress. Most techniques require arduous calibrations and necessitate extensive preparation of the receiving surfaces. However, the main draw back of instruments such as Preston tubes, hot films, buried wire gages, and floating element balances is that they only provide a point measurement. The advantages of capturing global shear data would be appreciable when compared with conventional point measurement sensors. It has yet to be determined if a repeatable correlation exists between the measured color of a liquid crystal coating and the magnitude/directional components of a shear vector imposed onto it.

Caprock Integrity during Hydrocarbon Production and CO2 Injection in the Goldeneye Reservoir

NASA Astrophysics Data System (ADS)

Salimzadeh, Saeed; Paluszny, Adriana; Zimmerman, Robert

2016-04-01

Carbon Capture and Storage (CCS) is a key technology for addressing climate change and maintaining security of energy supplies, while potentially offering important economic benefits. UK offshore, depleted hydrocarbon reservoirs have the potential capacity to store significant quantities of carbon dioxide, produced during power generation from fossil fuels. The Goldeneye depleted gas condensate field, located offshore in the UK North Sea at a depth of ~ 2600 m, is a candidate for the storage of at least 10 million tons of CO2. In this research, a fully coupled, full-scale model (50×20×8 km), based on the Goldeneye reservoir, is built and used for hydro-carbon production and CO2 injection simulations. The model accounts for fluid flow, heat transfer, and deformation of the fractured reservoir. Flow through fractures is defined as two-dimensional laminar flow within the three-dimensional poroelastic medium. The local thermal non-equilibrium between injected CO2 and host reservoir has been considered with convective (conduction and advection) heat transfer. The numerical model has been developed using standard finite element method with Galerkin spatial discretisation, and finite difference temporal discretisation. The geomechanical model has been implemented into the object-oriented Imperial College Geomechanics Toolkit, in close interaction with the Complex Systems Modelling Platform (CSMP), and validated with several benchmark examples. Fifteen major faults are mapped from the Goldeneye field into the model. Modal stress intensity factors, for the three modes of fracture opening during hydrocarbon production and CO2 injection phases, are computed at the tips of the faults by computing the I-Integral over a virtual disk. Contact stresses -normal and shear- on the fault surfaces are iteratively computed using a gap-based augmented Lagrangian-Uzawa method. Results show fault activation during the production phase that may affect the fault's hydraulic conductivity and its connection to the reservoir rocks. The direction of growth is downward during production and it is expected to be upward during injection. Elevated fluid pressures inside faults during CO2 injection may further facilitate fault activation by reducing normal effective stresses. Activated faults can act as permeable conduits and potentially jeopardise caprock integrity for CO2 storage purposes.

S-shaped flow curves of shear thickening suspensions: direct observation of frictional rheology.

PubMed

Pan, Zhongcheng; de Cagny, Henri; Weber, Bart; Bonn, Daniel

2015-09-01

We study the rheological behavior of concentrated granular suspensions of simple spherical particles. Under controlled stress, the system exhibits an S-shaped flow curve (stress vs shear rate) with a negative slope in between the low-viscosity Newtonian regime and the shear thickened regime. Under controlled shear rate, a discontinuous transition between the two states is observed. Stress visualization experiments with a fluorescent probe suggest that friction is at the origin of shear thickening. Stress visualization shows that the stress in the system remains homogeneous (no shear banding) if a stress is imposed that is intermediate between the high- and low-stress branches. The S-shaped shear thickening is then due to the discontinuous formation of a frictional force network between particles upon increasing the stress.

Quantification of wall shear stress in large blood vessels using Lagrangian interpolation functions with cine phase-contrast magnetic resonance imaging.

PubMed

Cheng, Christopher P; Parker, David; Taylor, Charles A

2002-09-01

Arterial wall shear stress is hypothesized to be an important factor in the localization of atherosclerosis. Current methods to compute wall shear stress from magnetic resonance imaging (MRI) data do not account for flow profiles characteristic of pulsatile flow in noncircular vessel lumens. We describe a method to quantify wall shear stress in large blood vessels by differentiating velocity interpolation functions defined using cine phase-contrast MRI data on a band of elements in the neighborhood of the vessel wall. Validation was performed with software phantoms and an in vitro flow phantom. At an image resolution corresponding to in vivo imaging data of the human abdominal aorta, time-averaged, spatially averaged wall shear stress for steady and pulsatile flow were determined to be within 16% and 23% of the analytic solution, respectively. These errors were reduced to 5% and 8% with doubling in image resolution. For the pulsatile software phantom, the oscillation in shear stress was predicted to within 5%. The mean absolute error of circumferentially resolved shear stress for the nonaxisymmetric phantom decreased from 28% to 15% with a doubling in image resolution. The irregularly shaped phantom and in vitro investigation demonstrated convergence of the calculated values with increased image resolution. We quantified the shear stress at the supraceliac and infrarenal regions of a human abdominal aorta to be 3.4 and 2.3 dyn/cm2, respectively.

Dynamic shear-stress-enhanced rates of nutrient consumption in gas-liquid semi-continuous-flow suspensions

NASA Astrophysics Data System (ADS)

Belfiore, Laurence A.; Volpato, Fabio Z.; Paulino, Alexandre T.; Belfiore, Carol J.

2011-12-01

The primary objective of this investigation is to establish guidelines for generating significant mammalian cell density in suspension bioreactors when stress-sensitive kinetics enhance the rate of nutrient consumption. Ultra-low-frequency dynamic modulations of the impeller (i.e., 35104 Hz) introduce time-dependent oscillatory shear into this transient analysis of cell proliferation under semi-continuous creeping flow conditions. Greater nutrient consumption is predicted when the amplitude A of modulated impeller rotation increases, and stress-kinetic contributions to nutrient consumption rates increase linearly at higher modulation frequency via an application of fluctuation-dissipation response. Interphase mass transfer is required to replace dissolved oxygen as it is consumed by aerobic nutrient consumption in the liquid phase. The theory and predictions described herein could be important at small length scales in the creeping flow regime where viscous shear is significant at the interface between the nutrient medium and isolated cells in suspension. Two-dimensional flow around spherically shaped mammalian cells, suspended in a Newtonian culture medium, is analyzed to calculate the surface-averaged magnitude of the velocity gradient tensor and modify homogeneous rates of nutrient consumption that are stimulated by viscous shear, via the formalism of stress-kinetic reciprocal relations that obey Curie's theorem in non-equilibrium thermodynamics. Time constants for stress-free free and stress-sensitive stress nutrient consumption are defined and quantified to identify the threshold (i.e., stress,threshold) below which the effect of stress cannot be neglected in accurate predictions of bioreactor performance. Parametric studies reveal that the threshold time constant for stress-sensitive nutrient consumption stress,threshold decreases when the time constant for stress-free nutrient consumption free is shorter. Hence, stress,threshold depends directly on free. In other words, the threshold rate of stress-sensitive nutrient consumption is higher when the stress-free rate of nutrient consumption increases. Modulated rotation of the impeller, superimposed on steady shear, increases stress,threshold when free is constant, and stress,threshold depends directly on the amplitude A of these angular velocity modulations.

Frictional strength and heat flow of southern San Andreas Fault

NASA Astrophysics Data System (ADS)

Zhu, P. P.

2016-01-01

Frictional strength and heat flow of faults are two related subjects in geophysics and seismology. To date, the investigation on regional frictional strength and heat flow still stays at the stage of qualitative estimation. This paper is concentrated on the regional frictional strength and heat flow of the southern San Andreas Fault (SAF). Based on the in situ borehole measured stress data, using the method of 3D dynamic faulting analysis, we quantitatively determine the regional normal stress, shear stress, and friction coefficient at various seismogenic depths. These new data indicate that the southern SAF is a weak fault within the depth of 15 km. As depth increases, all the regional normal and shear stresses and friction coefficient increase. The former two increase faster than the latter. Regional shear stress increment per kilometer equals 5.75 ± 0.05 MPa/km for depth ≤15 km; regional normal stress increment per kilometer is equal to 25.3 ± 0.1 MPa/km for depth ≤15 km. As depth increases, regional friction coefficient increment per kilometer decreases rapidly from 0.08 to 0.01/km at depths less than ~3 km. As depth increases from ~3 to ~5 km, it is 0.01/km and then from ~5 to 15 km, and it is 0.002/km. Previously, frictional strength could be qualitatively determined by heat flow measurements. It is difficult to obtain the quantitative heat flow data for the SAF because the measured heat flow data exhibit large scatter. However, our quantitative results of frictional strength can be employed to investigate the heat flow in the southern SAF. We use a physical quantity P f to describe heat flow. It represents the dissipative friction heat power per unit area generated by the relative motion of two tectonic plates accommodated by off-fault deformation. P f is called "fault friction heat." On the basis of our determined frictional strength data, utilizing the method of 3D dynamic faulting analysis, we quantitatively determine the regional long-term fault friction heat at various seismogenic depths in the southern SAF. The new data show that as depth increases, regional friction stress increases within the depth of 15 km; its increment per kilometer equals 5.75 ± 0.05 MPa/km. As depth increases, regional long-term fault friction heat increases; its increment per kilometer is equal to 3.68 ± 0.03 mW/m2/km. The values of regional long-term fault friction heat provided by this study are always lower than those from heat flow measurements. The difference between them and the scatter existing in the measured heat flow data are mainly caused by the following processes: (i) heat convection, (ii) heat advection, (iii) stress accumulation, (iv) seismic bursts between short-term lull periods in a long-term period, and (v) influence of seismicity in short-term periods upon long-term slip rate and heat flow. Fault friction heat is a fundamental parameter in research on heat flow.

The application of continuum damage mechanics to solve problems in geodynamics

NASA Astrophysics Data System (ADS)

Manaker, David Martin

Deformation within the Earth's lithosphere is largely controlled by the rheology of the rock. Ductile behavior in rocks is often associated with plasticity due to dislocation motion or diffusion under high pressures and temperatures. However, ductile behavior can also occur in brittle materials. An example would be cataclastic flow associated with folding at shallow crustal levels, steep subduction zones, and large-scale deformation at plate boundaries. Engineers utilize damage mechanics to model the continuum deformation of brittle materials. We utilize a modified form of damage mechanics where damage represents a reduction in frictional strength and includes a yield stress. We use this empirical approach to simulate the bending of the lithosphere. We use numerical simulations to obtain elastostatic solutions for plate bending and where the stress exceeds a yield stress, we apply damage to reduce the elastic moduli. Damage is calculated at each time step by a power-law relationship of the ratio of the yield stress to stress and the yield strain to the strain. To test our method, we apply our damage rheology to a plate deforming under applied shear, a constant bending moment, and a constant load. We simulate a wide range of behaviors from slow relaxation to instantaneous failure, over timescales that span six orders of magnitude. Stress relaxation produces elastic-perfectly plastic behavior in cases where failure does not occur. For cases of failure, we observe a rapid increase in damage leading to failure. The changes in the rate of damage accumulation in failure cases are similar to the changes in b-values of acoustic emissions observed in triaxial compression tests of fractured rock and b-value changes prior to some large earthquakes. Thus continuum damage mechanics can simulate ductile behavior due to brittle mechanisms as well as observations of laboratory experiments and seismicity.

Yield Hardening of Electrorheological Fluids in Channel Flow

NASA Astrophysics Data System (ADS)

Helal, Ahmed; Qian, Bian; McKinley, Gareth H.; Hosoi, A. E.

2016-06-01

Electrorheological fluids offer potential for developing rapidly actuated hydraulic devices where shear forces or pressure-driven flow are present. In this study, the Bingham yield stress of electrorheological fluids with different particle volume fractions is investigated experimentally in wall-driven and pressure-driven flow modes using measurements in a parallel-plate rheometer and a microfluidic channel, respectively. A modified Krieger-Dougherty model can be used to describe the effects of the particle volume fraction on the yield stress and is in good agreement with the viscometric data. However, significant yield hardening in pressure-driven channel flow is observed and attributed to an increase and eventual saturation of the particle volume fraction in the channel. A phenomenological physical model linking the densification and consequent microstructure to the ratio of the particle aggregation time scale compared to the convective time scale is presented and used to predict the enhancement in yield stress in channel flow, enabling us to reconcile discrepancies in the literature between wall-driven and pressure-driven flows.

Reynolds-Stress and Triple-Product Models Applied to a Flow with Rotation and Curvature

NASA Technical Reports Server (NTRS)

Olsen, Michael E.

2016-01-01

Turbulence models, with increasing complexity, up to triple product terms, are applied to the flow in a rotating pipe. The rotating pipe is a challenging case for turbulence models as it contains significant rotational and curvature effects. The flow field starts with the classic fully developed pipe flow, with a stationary pipe wall. This well defined condition is then subjected to a section of pipe with a rotating wall. The rotating wall introduces a second velocity scale, and creates Reynolds shear stresses in the radial-circumferential and circumferential-axial planes. Furthermore, the wall rotation introduces a flow stabilization, and actually reduces the turbulent kinetic energy as the flow moves along the rotating wall section. It is shown in the present work that the Reynolds stress models are capable of predicting significant reduction in the turbulent kinetic energy, but triple product improves the predictions of the centerline turbulent kinetic energy, which is governed by convection, dissipation and transport terms, as the production terms vanish on the pipe axis.

Enhancements to BISON U-Zr Metallic Fuel X447 Example Problem

DOE Office of Scientific and Technical Information (OSTI.GOV)

Galloway, Jack D.; Matthews, Christopher; Unal, Cetin

As development of a metallic fuel modeling capability in BISON has progressed, the need for an example problem used as a comparison basis was observed. Collaborative work between researchers at Los Alamos National Laboratory (LANL) and Idaho National Laboratory (INL) then proceeded to determine a viable rod to use as the basis and create a BISON input deck utilizing as many metallic fuel models as feasible. The basis chosen was what would be considered a generic rod from subassembly X447, an assembly irradiated in EBR-II towards the end of its operating life, heavily based on reported data for fuel pinmore » DP11. Thus, the approach was adopted to use flow characteristics from subassembly X447 as a basis for the convective heat transfer solution, power history and axial power profiles that are representative of rod DP11 from subassembly X447. The rod simulated is a U-10Zr wt% (U-22.5Zr at%) composition. A 2D-RZ mesh would be used to capture axial thermal hydraulic effects, axial swelling and stress-strain calculations over the full length of the rod. After initial work was invested, a refinement of the various models and input parameters was conducted to ensure consistency between operator-declared conditions, model input requirements and those represented in the example problem. This report serves as a synopsis of the enhancements and refinements to the example problem conducted throughout the 2016 fiscal year.« less

An easy to assemble microfluidic perfusion device with a magnetic clamp

PubMed Central

Tkachenko, Eugene; Gutierrez, Edgar; Ginsberg, Mark H.; Groisman, Alex

2009-01-01

We have built and characterized a magnetic clamp for reversible sealing of PDMS microfluidic chips against cover glasses with cell cultures and a microfluidic chip for experiments on shear stress response of endothelial cells. The magnetic clamp exerts a reproducible uniform pressure on the microfluidic chip, achieving fast and reliable sealing for liquid pressures up to 40 kPa inside the chip with <10% deformations of microchannels and minimal variations of the substrate shear stress in perfusion flow. The microfluidic chip has 8 test regions with the substrate shear stress varying by a factor of 2 between each region, thus covering a 128-fold range from low venous to arterial. The perfusion is driven by differential pressure, which makes it possible to create pulsatile flows mimicking pulsing in the vasculature. The setup is tested by 15 – 40 hours perfusions over endothelial monolayers with shear stress in the range of 0.07 - 9 dyn/cm2. Excellent cell viability at all shear stresses and alignment of cells along the flow at high shear stresses are repeatedly observed. A scratch wound healing assay under a shear flow is demonstrated and cell migration velocities are measured. Transfection of cells with a fluorescent protein is performed, and migrating fluorescent cells are imaged at a high resolution under shear flow in real time. The magnetic clamp can be closed with minimal mechanical perturbation to cells on the substrate and used with a variety of microfluidic chips for experiments with adherent and non-adherent cells. PMID:19350090

A New Critical State Model for Geomechanical Behavior of Methane Hydrate-Bearing Sands

NASA Astrophysics Data System (ADS)

Lin, J. S.; Xing, P.; Rutqvist, J.; Seol, Y.; Choi, J. H.

2014-12-01

Methane hydrate bearing sands behave like sands once the hydrate has dissociated, but could exhibit a substantial increase in the shear strength, stiffness and dilatancy as the degree of hydrate saturation increases. A new critical state model was developed that incorporates the spatially mobilized plane (SMP) concept, which has been proven effective in modeling mechanical behavior of sands. While this new model was built on the basic constructs of the critical state model, important enhancements were introduced. The model adopted the t-stress concept, which defined the normal and shear stress on the SMP, in describing the plastic behavior of the soil. In this connection the versatile Matsuoka-Nakai yield criterion was also employed, which defined the general three dimensional yield behavior. The resulting constitutive law was associated in the t-stress space, but became non-associated in the conventional p-q stress space as it should be for sands. The model also introduced a generalized degree of hydrate saturation concept that was modified from the pioneering work of the Cambridge group. The model gives stress change when the sands are subjected to straining, and/or to hydrate saturation changes. The performance of the model has been found satisfactory using data from laboratory triaxial tests on reconstituted samples and core samples taken from Nankai Trough, Japan. The model has been implemented into FLAC3D. A coupling example with the multiphase flow code, TOUGH+, is presented which simulates the mechanical behavior of a sample when the surrounding temperature has been raised, and the hydrate undergoes state change and no longer resides in the stability zone.

Bending the law: tidal bending and its effects on ice viscosity and flow

NASA Astrophysics Data System (ADS)

Rosier, S.; Gudmundsson, G. H.

2017-12-01

Many ice shelves are subject to strong ocean tides and, in order to accommodate this vertical motion, the ice must bend within the grounding zone. This tidal bending generates large stresses within the ice, changing its effective viscosity. For a confined ice shelf, this is particularly relevant because the tidal bending stresses occur along the sidewalls, which play an important role in the overall flow regime of the ice shelf. Hence, tidal bending stresses will affect both the mean and time-varying components of ice shelf flow. GPS measurements reveal strong variations in horizontal ice shelf velocities at a variety of tidal frequencies. We show, using full-Stokes viscoelastic modelling, that inclusion of tidal bending within the model accounts for much of the observed tidal modulation of horizontal ice shelf flow. Furthermore, our model shows that in the absence of a vertical tidal forcing, the mean flow of the ice shelf is reduced considerably.

A Rotary Flow Channel for Shear Stress Sensor Calibration

NASA Technical Reports Server (NTRS)

Zuckerwar, Allan J.; Scott, Michael A.

2004-01-01

A proposed shear sensor calibrator consists of a rotating wheel with the sensor mounted tangential to the rim and positioned in close proximity to the rim. The shear stress generated by the flow at the sensor position is simply tau(sub omega) = (mu)r(omega)/h, where mu is the viscosity of the ambient gas, r the wheel radius, omega the angular velocity of the wheel, and h the width of the gap between the wheel rim and the sensor. With numerical values of mu = 31 (mu)Pa s (neon at room temperature), r = 0.5 m, omega = 754 /s (7200 rpm), and h = 50.8 m, a shear stress of tau(sub omega) = 231 Pa can be generated. An analysis based on one-dimensional flow, with the flow velocity having only an angular component as a function of the axial and radial coordinates, yields corrections to the above simple formula for the curvature of the wheel, flatness of the sensor, and finite width of the wheel. It is assumed that the sensor mount contains a trough (sidewalls) to render a velocity release boundary condition at the edges of the rim. The Taylor number under maximum flow conditions is found to be 62.3, sufficiently low to obviate flow instability. The fact that the parameters entering into the evaluation of the shear stress can be measured to high accuracy with well-defined uncertainties makes the proposed calibrator suitable for a physical standard for shear stress calibration.

Flaw-induced plastic-flow dynamics in bulk metallic glasses under tension

PubMed Central

Chen, S. H.; Yue, T. M.; Tsui, C. P.; Chan, K. C.

2016-01-01

Inheriting amorphous atomic structures without crystalline lattices, bulk metallic glasses (BMGs) are known to have superior mechanical properties, such as high strength approaching the ideal value, but are susceptible to catastrophic failures. Understanding the plastic-flow dynamics of BMGs is important for achieving stable plastic flow in order to avoid catastrophic failures, especially under tension, where almost all BMGs demonstrate limited plastic flow with catastrophic failure. Previous findings have shown that the plastic flow of BMGs displays critical dynamics under compression tests, however, the plastic-flow dynamics under tension are still unknown. Here we report that power-law critical dynamics can also be achieved in the plastic flow of tensile BMGs by introducing flaws. Differing from the plastic flow under compression, the flaw-induced plastic flow under tension shows an upward trend in the amplitudes of the load drops with time, resulting in a stable plastic-flow stage with a power-law distribution of the load drop. We found that the flaw-induced plastic flow resulted from the stress gradients around the notch roots, and the stable plastic-flow stage increased with the increase of the stress concentration factor ahead of the notch root. The findings are potentially useful for predicting and avoiding the catastrophic failures in tensile BMGs by tailoring the complex stress fields in practical structural-applications. PMID:27779221

Flow and Jamming of Granular Materials in a Two-dimensional Hopper

NASA Astrophysics Data System (ADS)

Tang, Junyao

Flow in a hopper is both a fertile testing ground for understanding fundamental granular flow rheology and industrially highly relevant. Despite increasing research efforts in this area, a comprehensive physical theory is still lacking for both jamming and flow of granular materials in a hopper. In this work, I have designed a two dimensional (2D) hopper experiment using photoelastic particles (particles' shape: disk or ellipse), with the goal to build a bridge between macroscopic phenomenon of hopper flow and microscopic particle-scale dynamics. Through synchronized data of particle tracking and stress distributions in particles, I have shown differences between my data of the time-averaged velocity/stress profile of 2D hopper flow with previous theoretical predictions. I have also demonstrated the importance of a mechanical stable arch near the opening on controlling hopper flow rheology and suggested a heuristic phase diagram for the hopper flow/jamming transition. Another part of this thesis work is focused on studying the impact of particle shape of particles on hopper flow. By comparing particle-tracking and photoelastic data for ellipses and disks at the appropriate length scale, I have demonstrated an important role for the rotational freedom of elliptical particles in controlling flow rheology through particle tracking and stress analysis. This work has been supported by International Fine Particle Research Institute (IFPRI) .

DIRECT NUMERICAL SIMULATION OF TRANSITIONAL FLOW IN A STENOSED CAROTID BIFURCATION

PubMed Central

Lee, Seung E.; Lee, Sang-Wook; Fischer, Paul F.; Bassiouny, Hisham S.; Loth, Francis

2008-01-01

The blood flow dynamics of a stenosed, subject-specific, carotid bifurcation were numerically simulated using the spectral element method. Pulsatile inlet conditions were based on in vivo color Doppler ultrasound measurements of blood velocity. The results demonstrated the transitional or weakly turbulent state of the blood flow, which featured rapid velocity and pressure fluctuations in the post-stenotic region of the internal carotid artery during systole and laminar flow during diastole. High-frequency vortex shedding was greatest downstream of the stenosis during the deceleration phase of systole. Velocity fluctuations had a frequency within the audible range of 100–300 Hz. Instantaneous wall shear stress within the stenosis was relatively high during systole (~25-45 Pa) compared to that in a healthy carotid. In addition, high spatial gradients of wall shear stress were present due to flow separation on the inner wall. Oscillatory flow reversal and low pressure were observed distal to the stenosis in the internal carotid artery. This study predicts the complex flow field, the turbulence levels and the distribution of the biomechanical stresses present in vivo within a stenosed carotid artery. PMID:18656199

Numerical Issues for Circulation Control Calculations

NASA Technical Reports Server (NTRS)

Swanson, Roy C., Jr.; Rumsey, Christopher L.

2006-01-01

Steady-state and time-accurate two-dimensional solutions of the compressible Reynolds-averaged Navier- Stokes equations are obtained for flow over the Lockheed circulation control (CC) airfoil and the General Aviation CC (GACC) airfoil. Numerical issues in computing circulation control flows such as the effects of grid resolution, boundary and initial conditions, and unsteadiness are addressed. For the Lockheed CC airfoil computed solutions are compared with detailed experimental data, which include velocity and Reynolds stress profiles. Three turbulence models, having either one or two transport equations, are considered. Solutions are obtained on a sequence of meshes, with mesh refinement primarily concentrated on the airfoil circular trailing edge. Several effects related to mesh refinement are identified. For example, sometimes sufficient mesh resolution can exclude nonphysical solutions, which can occur in CC airfoil calculations. Also, sensitivities of the turbulence models with mesh refinement are discussed. In the case of the GACC airfoil the focus is on the difference between steady-state and time-accurate solutions. A specific objective is to determine if there is self-excited vortex shedding from the jet slot lip.

Application of a Full Reynolds Stress Model to High Lift Flows

NASA Technical Reports Server (NTRS)

Lee-Rausch, E. M.; Rumsey, C. L.; Eisfeld, B.

2016-01-01

A recently developed second-moment Reynolds stress model was applied to two challenging high-lift flows: (1) transonic flow over the ONERA M6 wing, and (2) subsonic flow over the DLR-F11 wing-body configuration from the second AIAA High Lift Prediction Workshop. In this study, the Reynolds stress model results were contrasted with those obtained from one- and two{equation turbulence models, and were found to be competitive in terms of the prediction of shock location and separation. For an ONERA M6 case, results from multiple codes, grids, and models were compared, with the Reynolds stress model tending to yield a slightly smaller shock-induced separation bubble near the wing tip than the simpler models, but all models were fairly close to the limited experimental surface pressure data. For a series of high-lift DLR{F11 cases, the range of results was more limited, but there was indication that the Reynolds stress model yielded less-separated results than the one-equation model near maximum lift. These less-separated results were similar to results from the one-equation model with a quadratic constitutive relation. Additional computations need to be performed before a more definitive assessment of the Reynolds stress model can be made.

Predicting the synergy of multiple stress effects

NASA Astrophysics Data System (ADS)

Liess, Matthias; Foit, Kaarina; Knillmann, Saskia; Schäfer, Ralf B.; Liess, Hans-Dieter

2016-09-01

Toxicants and other, non-chemical environmental stressors contribute to the global biodiversity crisis. Examples include the loss of bees and the reduction of aquatic biodiversity. Although non-compliance with regulations might be contributing, the widespread existence of these impacts suggests that for example the current approach of pesticide risk assessment fails to protect biodiversity when multiple stressors concurrently affect organisms. To quantify such multiple stress effects, we analysed all applicable aquatic studies and found that the presence of environmental stressors increases individual sensitivity to toxicants (pesticides, trace metals) by a factor of up to 100. To predict this dependence, we developed the “Stress Addition Model” (SAM). With the SAM, we assume that each individual has a general stress capacity towards all types of specific stress that should not be exhausted. Experimental stress levels are transferred into general stress levels of the SAM using the stress-related mortality as a common link. These general stress levels of independent stressors are additive, with the sum determining the total stress exerted on a population. With this approach, we provide a tool that quantitatively predicts the highly synergistic direct effects of independent stressor combinations.

Simultaneous imaging of blood flow dynamics and vascular remodelling during development.

PubMed

Ghaffari, Siavash; Leask, Richard L; Jones, Elizabeth A V

2015-12-01

Normal vascular development requires blood flow. Time-lapse imaging techniques have revolutionised our understanding of developmental biology, but measuring changes in blood flow dynamics has met with limited success. Ultrasound biomicroscopy and optical coherence tomography can concurrently image vascular structure and blood flow velocity, but these techniques lack the resolution to accurately calculate fluid forces such as shear stress. This is important because hemodynamic forces are biologically active and induce changes in the expression of genes important for vascular development. Regional variations in shear stress, rather than the overall level, control processes such as vessel enlargement and regression during vascular remodelling. We present a technique to concurrently visualise vascular remodelling and blood flow dynamics. We use an avian embryonic model and inject an endothelial-specific dye and fluorescent microspheres. The motion of the microspheres is captured with a high-speed camera and the velocity of the blood flow in and out of the region of interest is quantified by micro-particle image velocitymetry (µPIV). The vessel geometry and flow are used to numerically solve the flow physics with computational fluid dynamics (CFD). Using this technique, we can analyse changes in shear stress, pressure drops and blood flow velocities over a period of 10 to 16 h. We apply this to study the relationship between shear stress and chronic changes in vessel diameter during embryonic development, both in normal development and after TGFβ stimulation. This technique allows us to study the interaction of biomolecular and biomechanical signals during vascular remodelling using an in vivo developmental model. © 2015. Published by The Company of Biologists Ltd.

Effects of insulin on physical factors: atherosclerosis in diabetes mellitus.

PubMed

McMillan, D E

1985-12-01

Newton's laws of motion play a major role in blood flow. Inertia and conservation of momentum cause flow to separate at branches and curves in large blood vessels. Areas of separated flow in the arterial system are sites of atherogenesis. The place at which the separation ends, called the stagnation point, is the focus for plaque development. Pulsation of the arterial circulation causes the stagnation point to move downstream with each systole and upstream with each diastole. This movement generates forward and backward shearing force in the stagnation region as the separated flow migrates back and forth. Angular momentum, introduced into flowing blood with each heart beat and further enhanced by the asymmetry of origin of vessels branching from the aorta, generates a sidewise force component that is preserved during migration of the stagnation point. The sidewise force, added to the forward and backward shear stresses, creates an area of multidirectional shear stress under the migrating stagnation point that increases the permeability of the local endothelium. Blood is a complex fluid; it can generate greater shear stresses near the stagnation point than the simple fluids normally studied by fluid mechanicists. Blood is capable of retaining shear stress for short periods after it ceases to flow and extra work is required to establish its flow. In diabetes, reduced erythrocyte deformability further burdens flow onset. We are not yet able to establish whether the increase is only a few percent, or whether the burden is larger. Whatever its magnitude, diabetic modifications of the flow properties of blood, directly affect the size, location, and rate of development of atherosclerotic plaques.

Grain Flow at High Stresses

NASA Astrophysics Data System (ADS)

McSaveney, M. J.

2015-12-01

The transport mechanism of rapid long-runout rock avalanches was a hotly debated topic when I came on the scene in 1967. So how come it is still debated today? My explanation is that it is the expected outcome of peer review, poor comprehension, and technological advances outpacing intellectual advances. Why think about the problem when we can model it! So let us think about the problem. Shreve thought that rock avalanches fell upon and trapped a layer of air. What physics was he thinking about? It is how feathers and tissue papers fall. When my rock avalanches fly, they fly like unlubricated bricks using the physics of projectiles and ballistics. But the main transport mechanism is not flight. The dominant impression from watching a rock avalanche in motion is of fluid flow, as Heim described it in 1882. A rock avalanche is a very large grain flow. Bagnold studied dispersive grain flows, but why should one assume that rock avalanches are dispersive grain flows as many do. The more common grain flow type is a dense grain flow and rock avalanches are dense grain flows in which the weight can and does generate very high stresses at grain contacts. Brittle rock deforms elastically up to its compressive strength, whereupon it breaks, releasing elastic strain as transient elastic strain (seismic energy to a seismologist, acoustic energy to a physicist). Melosh and others have shown that acoustic energy can fluidize a grain mass. There is no exotic physics behind grain flow at high stress. When grains break, the released elastic strain has to go somewhere, and it goes somewhere principally by transmission though grain contacts. Depending on the state of stress at the grain contact, the contact will pass the stress or will slip at conventional values of Coulomb friction. Enough thinking! A physical model of the entire process is too big for any laboratory. So whose numerical model will do it?

Search for subgrid scale parameterization by projection pursuit regression

NASA Technical Reports Server (NTRS)

Meneveau, C.; Lund, T. S.; Moin, Parviz

1992-01-01

The dependence of subgrid-scale stresses on variables of the resolved field is studied using direct numerical simulations of isotropic turbulence, homogeneous shear flow, and channel flow. The projection pursuit algorithm, a promising new regression tool for high-dimensional data, is used to systematically search through a large collection of resolved variables, such as components of the strain rate, vorticity, velocity gradients at neighboring grid points, etc. For the case of isotropic turbulence, the search algorithm recovers the linear dependence on the rate of strain (which is necessary to transfer energy to subgrid scales) but is unable to determine any other more complex relationship. For shear flows, however, new systematic relations beyond eddy viscosity are found. For the homogeneous shear flow, the results suggest that products of the mean rotation rate tensor with both the fluctuating strain rate and fluctuating rotation rate tensors are important quantities in parameterizing the subgrid-scale stresses. A model incorporating these terms is proposed. When evaluated with direct numerical simulation data, this model significantly increases the correlation between the modeled and exact stresses, as compared with the Smagorinsky model. In the case of channel flow, the stresses are found to correlate with products of the fluctuating strain and rotation rate tensors. The mean rates of rotation or strain do not appear to be important in this case, and the model determined for homogeneous shear flow does not perform well when tested with channel flow data. Many questions remain about the physical mechanisms underlying these findings, about possible Reynolds number dependence, and, given the low level of correlations, about their impact on modeling. Nevertheless, demonstration of the existence of causal relations between sgs stresses and large-scale characteristics of turbulent shear flows, in addition to those necessary for energy transfer, provides important insight into the relation between scales in turbulent flows.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bouchard, P.J.

A forthcoming revision to the R6 Leak-before-Break Assessment Procedure is briefly described. Practical application of the LbB concepts to safety-critical nuclear plant is illustrated by examples covering both low temperature and high temperature (>450{degrees}C) operating regimes. The examples highlight a number of issues which can make the development of a satisfactory LbB case problematic: for example, coping with highly loaded components, methodology assumptions and the definition of margins, the effect of crack closure owing to weld residual stresses, complex thermal stress fields or primary bending fields, the treatment of locally high stresses at crack intersections with free surfaces, the choicemore » of local limit load solution when predicting ligament breakthrough, and the scope of calculations required to support even a simplified LbB case for high temperature steam pipe-work systems.« less

Strike-slip faulting, wrinkle ridges, and time variable stress states in the Coprates Region of Mars

NASA Technical Reports Server (NTRS)

Schultz, Richard A.

1990-01-01

The existence of strike-slip faults was recently documented in two locations on Mars. Two clear examples are reviewed located southeast of Valles Marineris and preliminary evidence is presented for more widespread strike-slip deformation elsewhere in Coprates. The first two examples show that strike-slip faulting occurred in a broad zone east of the Coprates Rise spanning approximately 400 km east-west by perhaps 1000 km north-south. The last example suggests that the growth of major wrinkle ridges throughout Coprates may have been influenced by horizontally directed shear stresses and that more than one generation of ridges was produced. Thus, 'compressional' deformation of ridged plains south of Valles Marineris was spatially heterogeneous and a temporal change in stress may have been involved.

Modelling the effect of hydrological change on estuarine health: An Australian Perspective. (Invited)

NASA Astrophysics Data System (ADS)

Bruce, L. C.; Adiyanti, S.; Ruibal, A. L.; Hipsey, M. R.

2013-12-01

Estuaries provide an important role in the filtering and transformation of carbon and nutrients from coastal catchments into the marine environment. Global trends including climate change, increased population, industrialization and agriculture have led to the rapid deterioration of estuarine ecosystems across the world. Within the Australian context, a particular concern is how changes to hydrological regimes, due to both water diversions and climate variability, are contributing to increased stress and consequent decline in estuarine health. In this study we report the modeling output of five Australian estuaries, each with different hydrological regimes and alternative management issues relating to altered hydrology: 1) The Yarra River estuary is a highly urbanized system, also receiving agriculturally derived nutrients, where the concern is the role of periodic hypoxia in reducing the assimilation capacity of nitrogen and thus increased risk of algal blooms forming in the coastal environment; 2) The upper Swan River estuary in Western Australia, which experiences persistent anoxia and hypoxia brought about by reduced flows has led to the commissioning of several oxygenation plants to alleviate stress on biodiversity and overall estuarine health; 3) The health of the Caboolture estuary in Queensland has deteriorated in the past decade with the aim of model development to quantify the various sources of surface and groundwater derived nutrients; 4) The construction of an additional channel to increase flushing in the Peel Harvey estuary in Western Australia was designed to control persistent harmful algal blooms; and 5) The Lower River Murray estuary experienced a prolonged drought that led to the development of acid sulfate soils and acid drainage deteriorating water quality. For these applications we applied 3-D hydrodynamic-biogeochemical models to determine underlying relationships between altered flow regimes, increased temperatures and the response of relevant estuarine health indicators. In general terms, the greatest threat identified was an increasing trend towards low flow conditions, both during winter and summer months beyond the usual pattern of flow variability. Minimum flows required to maintain estuarine health were determined using the models. In order to support management decisions related to environmental flow allocation and other interventions, examples of how the high frequency model output can be used to develop simple ';reduced' models that relate parameters of estuarine health to hydrological variability are described. Areas where further research is required to improve our understanding of estuarine response to hydrological change are discussed.

Regional cutaneous microvascular flow responses during gravitational and LBNP stresses

NASA Technical Reports Server (NTRS)

Breit, Gregory A.; Watenpaugh, Donald E.; Ballard, Richard E.; Murthy, Gita; Hargens, Alan R.

1993-01-01

Due to the regional variability of local hydrostatic pressures, microvascular flow responses to gravitational stress probably vary along the length of the body. Although these differences in local autoregulation have been observed previously during whole-body tilting, they have not been investigated during application of artificial gravitational stresses, such as lower body negative pressure or high gravity centrifugation. Although these stresses can create equivalent G-levels at the feet, they result in distinct distributions of vascular transmural pressure along the length of the body, and should consequently elicit different magnitudes and distributions of microvascular response. In the present study, the effects of whole-body tilting and lower body negative pressure on the level and distribution of microvascular flows within skin along the length of the body were compared.

Estimation of left ventricular blood flow parameters: clinical application of patient-specific CFD simulations from 4D echocardiography

NASA Astrophysics Data System (ADS)

Larsson, David; Spühler, Jeannette H.; Günyeli, Elif; Weinkauf, Tino; Hoffman, Johan; Colarieti-Tosti, Massimiliano; Winter, Reidar; Larsson, Matilda

2017-03-01

Echocardiography is the most commonly used image modality in cardiology, assessing several aspects of cardiac viability. The importance of cardiac hemodynamics and 4D blood flow motion has recently been highlighted, however such assessment is still difficult using routine echo-imaging. Instead, combining imaging with computational fluid dynamics (CFD)-simulations has proven valuable, but only a few models have been applied clinically. In the following, patient-specific CFD-simulations from transthoracic dobutamin stress echocardiography have been used to analyze the left ventricular 4D blood flow in three subjects: two with normal and one with reduced left ventricular function. At each stress level, 4D-images were acquired using a GE Vivid E9 (4VD, 1.7MHz/3.3MHz) and velocity fields simulated using a presented pathway involving endocardial segmentation, valve position identification, and solution of the incompressible Navier-Stokes equation. Flow components defined as direct flow, delayed ejection flow, retained inflow, and residual volume were calculated by particle tracing using 4th-order Runge-Kutta integration. Additionally, systolic and diastolic average velocity fields were generated. Results indicated no major changes in average velocity fields for any of the subjects. For the two subjects with normal left ventricular function, increased direct flow, decreased delayed ejection flow, constant retained inflow, and a considerable drop in residual volume was seen at increasing stress. Contrary, for the subject with reduced left ventricular function, the delayed ejection flow increased whilst the retained inflow decreased at increasing stress levels. This feasibility study represents one of the first clinical applications of an echo-based patient-specific CFD-model at elevated stress levels, and highlights the potential of using echo-based models to capture highly transient flow events, as well as the ability of using simulation tools to study clinically complex phenomena. With larger patient studies planned for the future, and with the possibility of adding more anatomical features into the model framework, the current work demonstrates the potential of patient-specific CFD-models as a tool for quantifying 4D blood flow in the heart.

Measurement and computation of hydrodynamic coupling at an air/water interface with an insoluble monolayer

NASA Astrophysics Data System (ADS)

Hirsa, Amir H.; Lopez, Juan M.; Miraghaie, Reza

2001-09-01

The coupling between a bulk vortical flow and a surfactant-influenced air/water interface has been examined in a canonical flow geometry through experiments and computations. The flow in an annular region bounded by stationary inner and outer cylinders is driven by the constant rotation of the floor and the free surface is initially covered by a uniformly distributed insoluble monolayer. When driven slowly, this geometry is referred to as the deep-channel surface viscometer and the flow is essentially azimuthal. The only interfacial property that affects the flow in this regime is the surface shear viscosity, [mu]s, which is uniform on the surface due to the vanishingly small concentration gradient. However, when operated at higher Reynolds number, secondary flow drives the surfactant film towards the inner cylinder until the Marangoni stress balances the shear stress on the bulk fluid. In general, the flow can be influenced by the surface tension, [sigma], and the surface dilatational viscosity, [kappa]s, as well as [mu]s. However, because of the small capillary number of the present flow, the effects of surface tension gradients dominate the surface viscosities in the radial stress balance, and the effect of [mu]s can only come through the azimuthal stress. Vitamin K1 was chosen for this study since it forms a well-behaved insoluble monolayer on water and [mu]s is essentially zero in the range of concentration on the surface, c, encountered. Thus the effect of Marangoni elasticity on the interfacial stress could be isolated. The flow near the interface was measured in an optical channel using digital particle image velocimetry. Steady axisymmetric flow was observed at the nominal Reynolds number of 8500. A numerical model has been developed using the axisymmetric Navier Stokes equations to examine the details of the coupling between the bulk and the interface. The nonlinear equation of state, [sigma](c), for the vitamin K1 monolayer was measured and utilized in the computations. Agreement was demonstrated between the measurements and computations, but the flow is critically dependent on the nonlinear equation of state.

Non-local rheology of stony debris flow propagating over a cohesionless sediment bed

NASA Astrophysics Data System (ADS)

Lanzoni, Stefano; Gregoretti, Carlo

2016-04-01

Velocity profiles of gravel-water mixtures observed in flume experiments often exhibit a double-slope behavior, with a lower narrower region where the velocity increases slowly, and an upper wider region often exhibiting a nearly linear behavior. Even though the flow can be classified within the grain-inertia regime, the overall profile seems to not conform to the power law (with exponent 1.5) distribution obtained by integrating along the normal to the flow the dispersive stresses envisaged by Bagnold (1954) in his pioneer work. Note that this formulation neglects the contribution to the velocity profile of the quasi-static (frictional) stresses that tend to dominate close to an erodible sediment bottom. The present work investigates the possibility to find out a uniformly valid distribution of shear stress from the bottom to the flow surface. To this aim we follow a heuristic coherence length approach (GDR-MIDI, 2004) similar to the mixing length procedure commonly used to study the atmospheric boundary layer over canopy (see, e.g., Harmann and Finnegan, 2007). A database built on 64 systematic debris flow experiments is used to disclose the general features of velocity profiles that establish within the body of almost steady water-sediment flows and the dependence of transport sediment volumetric concentration on the relevant parameters. The almost steady water-sediment flows considered in the study were generated by releasing a prescribed water discharge on a saturated layer of sediment (specifically, 3 mm gravel, 6 mm gravel, and 3 mm glass spheres) initially placed in a 10 m long and 0.2 m wide laboratory flume. The analysis clearly indicates that stony debris flow conditions characterized the experiments. The mixing length does not result constant, as required by a Bagnold-like profile, but varies gradually, from zero at the flow surface, to a finite value near the erodible bottom. We discuss this structure in terms of shear stress distribution along the normal to the flow, with particular attention to the role played by frictional stresses near to the movable bed over which the debris flow propagates.

Flow of a Casson fluid through a locally-constricted porous channel: a numerical study

NASA Astrophysics Data System (ADS)

Amlimohamadi, Haleh; Akram, Maryammosadat; Sadeghy, Kayvan

2016-05-01

Flow of a Casson fluid through a two-dimensional porous channel containing a local constriction is numerically investigated assuming that the resistance offered by the porous medium obeys the Darcy's law. Treating the constriction as another porous medium which obeys the Darcy-Forcheimer model, the equations governing fluid flow in the main channel and the constriction itself are numerically solved using the finite-volume method (FVM) based on the pseudo-transient SIMPLE algorithm. It is shown that an increase in the porosity of the channel decreases the shear stress exerted on the constriction. On the other hand, an increase in the fluid's yield stress is predicted to increase the maximum shear stress experienced by the constriction near its crest. The porosity of the constriction itself is predicted to have a negligible effect on the plaque's shear stress. But, the momentum of the weak flow passing through the constriction is argued to lower the bulk fluid from separating downstream of the constriction.

Effects of wall curvature on turbulence statistics

NASA Technical Reports Server (NTRS)

Moser, R. D.; Moin, P.

1985-01-01

A three-dimensional, time-dependent, direct numerical simulation of low-Reynolds number turbulent flow in a mildly curved channel was performed, and the results examined to determine the mechanism by which curvature affects wall-bounded turbulent shear flows. A spectral numerical method with about one-million modes was employed, and no explicit subgrid scale model was used. The effects of curvature on this flow were determined by comparing the concave and convex sides of the channel. The observed effects are consistent with experimental observations for mild curvature. The most significant difference in the turbulence statistics between the concave and convex sides is in the Reynolds shear stress. This is accompanied by significant differences in the terms of the Reynolds shear stress balance equations. In addition, it was found that stationary Taylor-Goertler vortices were present and that they had a significant effect on the flow by contributing to the mean Reynolds shear stress, and by enhancing the difference between the wall shear stresses.

Elastic Instability of Slender Rods in Steady Shear Flow Yields Positive First Normal Stress Differences

NASA Astrophysics Data System (ADS)

Becker, Leif E.; Shelley, Michael J.

2000-11-01

First normal stress differences in shear flow are a fundamental property of Non-Newtonian fluids. Experiments involving dilute suspensions of slender fibers exhibit a sharp transition to non-zero normal stress differences beyond a critical shear rate, but existing continuum theories for rigid rods predict neither this transition nor the corresponding magnitude of this effect. We present the first conclusive evidence that elastic instabilities are predominantly responsible for observed deviations from the dilute suspension theory of rigid rods. Our analysis is based on slender body theory and the equilibrium equations of elastica. A straight slender body executing its Jeffery orbit in Couette flow is subject to axial fluid forcing, alternating between compression and tension. We present a stability analysis showing that elastic instabilities are possible for strong flows. Simulations give the fully non-linear evolution of this shape instability, and show that flexibility of the fibers alone is sufficient to cause both shear-thinning and significant first normal stress differences.

Stent implantation influence wall shear stress evolution

NASA Astrophysics Data System (ADS)

Bernad, S. I.; Totorean, A. F.; Bosioc, A. I.; Petre, I.; Bernad, E. S.

2016-06-01

Local hemodynamic factors are known affect the natural history of the restenosis critically after coronary stenting of atherosclerosis. Stent-induced flows disturbance magnitude dependent directly on the strut design. The impact of flow alterations around struts vary as the strut geometrical parameters change. Our results provide data regarding the hemodynamic parameters for the blood flow in both stenosed and stented coronary artery under physiological conditions, namely wall shear stress and pressure drop.

Investigating Flow-Structure Interactions in Cerebral Aneurysms

ScienceCinema

None

2018-06-05

Visualization of blood flow in a cerebral aneurysm. Streamlines (colored by fluid velocity magnitude) reveal the complexity of the flow, isocontours of vorticity show blood vortex structures (colored by pressure), and the flexible arterial wall is colored by the stress magnitude, where regions in red indicate areas of high stress. Credits: Science: Paris Perdikaris, Yue Yu, George Em. Karniadakis and Leopold Grinberg Visualization: Joseph A. Insley and Michael E. Papka

Effect of intermittent shear stress on corneal epithelial cells using an in vitro flow culture model.

PubMed

Hampel, Ulrike; Garreis, Fabian; Burgemeister, Fabian; Eßel, Nicole; Paulsen, Friedrich

2018-04-27

The aim of this study was to establish and to evaluate an in vitro model for culturing human telomerase-immortalized corneal epithelial (hTCEpi) cells under adjustable medium flow mimicking the movements of the tear film on the ocular surface. Using an IBIDI pump system, cells were cultured under unidirectional, continuous or oscillating, discontinuous medium flow. Cell surface and cytoskeletal architecture were investigated by scanning electron microscopy and immunofluorescence. Gene expression of e-cadherin, occludin, tight junction protein (TJP), desmoplakin, desmocollin and mucins was investigated by real-time PCR. Protein expression of desmoplakin, TJP, occludin and e-cadherin was analyzed by western blot and localization was detected by immunofluorescence. Rose bengal staining was used to assess mucin (MUC) barrier integrity. MUC1, -4 and -16 proteins were localized by immunofluorescence. Medium flow-induced shear stress dramatically changed cellular morphology of hTCEpi. Cells subjected to discontinuous shear stress displayed the typical flattened, polygonal cell shape of the superficial layer of stratified squamous epithelia. Cell surfaces showed less bulging under shear stress and less extracellular gaps. The mRNA expression of E-cadherin, occludin and TJP were increased under oscillatory medium flow. Desmoplakin and occludin protein were upregulated under oscillatory shear stress. Stress fiber formation was not aligned to flow direction. MUC1, -4, and -16 protein were localized under all culture conditions, a regulation on mRNA expression was not detectable. Rose Bengal uptake was diminished under unidirectional conditions. Our findings suggest that shear stress as it occurs at the ocular surface during blinking exerts marked effects on corneal epithelial cells, such as changes in cellular morphology and expression of cell junctions. The described model may be useful for in vitro investigations of ocular surface epithelia as it represents a much more physiologic reproduction of the in vivo situation than the commonly applied static culture conditions. Copyright © 2018. Published by Elsevier Inc.

Constitutive Equations and ANN Approach to Predict the Flow Stress of Ti-6Al-4V Alloy Based on ABI Tests

NASA Astrophysics Data System (ADS)

Wang, Fuzeng; Zhao, Jun; Zhu, Ningbo

2016-11-01

The flow behavior of Ti-6Al-4V alloy was studied by automated ball indentation (ABI) tests in a wide range of temperatures (293, 493, 693, and 873 K) and strain rates (10-6, 10-5, and 10-4 s-1). Based on the experimental true stress-plastic strain data derived from the ABI tests, the Johnson-Cook (JC), Khan-Huang-Liang (KHL) and modified Zerilli-Armstrong (ZA) constitutive models, as well as artificial neural network (ANN) methods, were employed to predict the flow behavior of Ti-6Al-4V. A comparative study was made on the reliability of the four models, and their predictability was evaluated in terms of correlation coefficient ( R) and mean absolute percentage error. It is found that the flow stresses of Ti-6Al-4V alloy are more sensitive to temperature than strain rate under current experimental conditions. The predicted flow stresses obtained from JC model and KHL model show much better agreement with the experimental results than modified ZA model. Moreover, the ANN model is much more efficient and shows a higher accuracy in predicting the flow behavior of Ti-6Al-4V alloy than the constitutive equations.

Modeling the Effects of Cu Content and Deformation Variables on the High-Temperature Flow Behavior of Dilute Al-Fe-Si Alloys Using an Artificial Neural Network.

PubMed

Shakiba, Mohammad; Parson, Nick; Chen, X-Grant

2016-06-30

The hot deformation behavior of Al-0.12Fe-0.1Si alloys with varied amounts of Cu (0.002-0.31 wt %) was investigated by uniaxial compression tests conducted at different temperatures (400 °C-550 °C) and strain rates (0.01-10 s -1 ). The results demonstrated that flow stress decreased with increasing deformation temperature and decreasing strain rate, while flow stress increased with increasing Cu content for all deformation conditions studied due to the solute drag effect. Based on the experimental data, an artificial neural network (ANN) model was developed to study the relationship between chemical composition, deformation variables and high-temperature flow behavior. A three-layer feed-forward back-propagation artificial neural network with 20 neurons in a hidden layer was established in this study. The input parameters were Cu content, temperature, strain rate and strain, while the flow stress was the output. The performance of the proposed model was evaluated using the K-fold cross-validation method. The results showed excellent generalization capability of the developed model. Sensitivity analysis indicated that the strain rate is the most important parameter, while the Cu content exhibited a modest but significant influence on the flow stress.

Modeling the Effects of Cu Content and Deformation Variables on the High-Temperature Flow Behavior of Dilute Al-Fe-Si Alloys Using an Artificial Neural Network

PubMed Central

Shakiba, Mohammad; Parson, Nick; Chen, X.-Grant

2016-01-01

The hot deformation behavior of Al-0.12Fe-0.1Si alloys with varied amounts of Cu (0.002–0.31 wt %) was investigated by uniaxial compression tests conducted at different temperatures (400 °C–550 °C) and strain rates (0.01–10 s−1). The results demonstrated that flow stress decreased with increasing deformation temperature and decreasing strain rate, while flow stress increased with increasing Cu content for all deformation conditions studied due to the solute drag effect. Based on the experimental data, an artificial neural network (ANN) model was developed to study the relationship between chemical composition, deformation variables and high-temperature flow behavior. A three-layer feed-forward back-propagation artificial neural network with 20 neurons in a hidden layer was established in this study. The input parameters were Cu content, temperature, strain rate and strain, while the flow stress was the output. The performance of the proposed model was evaluated using the K-fold cross-validation method. The results showed excellent generalization capability of the developed model. Sensitivity analysis indicated that the strain rate is the most important parameter, while the Cu content exhibited a modest but significant influence on the flow stress. PMID:28773658

Impaired flow-induced dilation in mesenteric resistance arteries from mice lacking vimentin.

PubMed Central

Henrion, D; Terzi, F; Matrougui, K; Duriez, M; Boulanger, C M; Colucci-Guyon, E; Babinet, C; Briand, P; Friedlander, G; Poitevin, P; Lévy, B I

1997-01-01

The intermediate filament vimentin might play a key role in vascular resistance to mechanical stress. We investigated the responses to pressure (tensile stress) and flow (shear stress) of mesenteric resistance arteries perfused in vitro from vimentin knockout mice. Arteries were isolated from homozygous (Vim-/-, n = 14) or heterozygous vimentin-null mice (Vim+/-, n = 5) and from wild-type littermates (Vim+/+, n = 9). Passive arterial diameter (175+/-15 micron in Vim+/+ at 100 mmHg) and myogenic tone were not affected by the absence of vimentin. Flow-induced (0-150 microl/min) dilation (e. g., 19+/-3 micron dilation at 150 mmHg in Vim+/+) was significantly attenuated in Vim-/- mice (13+/-2 micron dilation, P < 0.01). Acute blockade of nitric oxide synthesis (NG-nitro- L-arginine, 10 microM) significantly decreased flow-induced dilation in both groups, whereas acute blockade of prostaglandin synthesis (indomethacin, 10 microM) had no significant effect. Mean blood pressure, in vivo mesenteric blood flow and diameter, and mesenteric artery media thickness or media to lumen ratio were not affected by the absence of vimentin. Thus, the absence of vimentin decreased selectively the response of resistance arteries to flow, suggesting a role for vimentin in the mechanotransduction of shear stress. PMID:9389758

Deformation structure analysis of material at fatigue on the basis of the vector field

NASA Astrophysics Data System (ADS)

Kibitkin, Vladimir V.; Solodushkin, Andrey I.; Pleshanov, Vasily S.

2017-12-01

In the paper, spatial distributions of deformation, circulation, and shear amplitudes and shear angles are obtained from the displacement vector field measured by the DIC technique. This vector field and its characteristics of shears and vortices are given as an example of such approach. The basic formulae are also given. The experiment shows that honeycomb deformation structures can arise in the center of a macrovortex at developed plastic flow. The spatial distribution of local circulation and shears is discovered, which coincides with the deformation structure but their amplitudes are different. The analysis proves that the spatial distribution of shear angles is a result of maximum tangential and normal stresses. The anticlockwise circulation of most local vortices obeys the normal Gaussian law in the area of interest.

Discrete ellipsoidal statistical BGK model and Burnett equations

NASA Astrophysics Data System (ADS)

Zhang, Yu-Dong; Xu, Ai-Guo; Zhang, Guang-Cai; Chen, Zhi-Hua; Wang, Pei

2018-06-01

A new discrete Boltzmann model, the discrete ellipsoidal statistical Bhatnagar-Gross-Krook (ESBGK) model, is proposed to simulate nonequilibrium compressible flows. Compared with the original discrete BGK model, the discrete ES-BGK has a flexible Prandtl number. For the discrete ES-BGK model in the Burnett level, two kinds of discrete velocity model are introduced and the relations between nonequilibrium quantities and the viscous stress and heat flux in the Burnett level are established. The model is verified via four benchmark tests. In addition, a new idea is introduced to recover the actual distribution function through the macroscopic quantities and their space derivatives. The recovery scheme works not only for discrete Boltzmann simulation but also for hydrodynamic ones, for example, those based on the Navier-Stokes or the Burnett equations.

Structure of thermal pair clouds around gamma-ray-emitting black holes

NASA Technical Reports Server (NTRS)

Liang, Edison P.

1991-01-01

Using certain simplifying assumptions, the general structure of a quasi-spherical thermal pair-balanced cloud surrounding an accreting black hole is derived from first principles. Pair-dominated hot solutions exist only for a restricted range of the viscosity parameter. These results are applied as examples to the 1979 HEAO 3 gamma-ray data of Cygnus X-1 and the Galactic center. Values are obtained for the viscosity parameter lying in the range of about 0.1-0.01. Since the lack of synchrotron soft photons requires the magnetic field to be typically less than 1 percent of the equipartition value, a magnetic field cannot be the main contributor to the viscous stress of the inner accretion flow, at least during the high gamma-ray states.

On the modelling of scalar and mass transport in combustor flows

NASA Technical Reports Server (NTRS)

Nikjooy, M.; So, R. M. C.

1989-01-01

Results are presented of a numerical study of swirling and nonswirling combustor flows with and without density variations. Constant-density arguments are used to justify closure assumptions invoked for the transport equations for turbulent momentum and scalar fluxes, which are written in terms of density-weighted variables. Comparisons are carried out with measurements obtained from three different axisymmetric model combustor experiments covering recirculating flow, swirling flow, and variable-density swirling flow inside the model combustors. Results show that the Reynolds stress/flux models do a credible job of predicting constant-density swirling and nonswirling combustor flows with passive scalar transport. However, their improvements over algebraic stress/flux models are marginal. The extension of the constant-density models to variable-density flow calculations shows that the models are equally valid for such flows.

Visualization of three pathways for macromolecule transport across cultured endothelium and their modification by flow.

PubMed

Ghim, Mean; Alpresa, Paola; Yang, Sung-Wook; Braakman, Sietse T; Gray, Stephen G; Sherwin, Spencer J; van Reeuwijk, Maarten; Weinberg, Peter D

2017-11-01

Transport of macromolecules across vascular endothelium and its modification by fluid mechanical forces are important for normal tissue function and in the development of atherosclerosis. However, the routes by which macromolecules cross endothelium, the hemodynamic stresses that maintain endothelial physiology or trigger disease, and the dependence of transendothelial transport on hemodynamic stresses are controversial. We visualized pathways for macromolecule transport and determined the effect on these pathways of different types of flow. Endothelial monolayers were cultured under static conditions or on an orbital shaker producing different flow profiles in different parts of the wells. Fluorescent tracers that bound to the substrate after crossing the endothelium were used to identify transport pathways. Maps of tracer distribution were compared with numerical simulations of flow to determine effects of different shear stress metrics on permeability. Albumin-sized tracers dominantly crossed the cultured endothelium via junctions between neighboring cells, high-density lipoprotein-sized tracers crossed at tricellular junctions, and low-density lipoprotein-sized tracers crossed through cells. Cells aligned close to the angle that minimized shear stresses across their long axis. The rate of paracellular transport under flow correlated with the magnitude of these minimized transverse stresses, whereas transport across cells was uniformly reduced by all types of flow. These results contradict the long-standing two-pore theory of solute transport across microvessel walls and the consensus view that endothelial cells align with the mean shear vector. They suggest that endothelial cells minimize transverse shear, supporting its postulated proatherogenic role. Preliminary data show that similar tracer techniques are practicable in vivo. NEW & NOTEWORTHY Solutes of increasing size crossed cultured endothelium through intercellular junctions, through tricellular junctions, or transcellularly. Cells aligned to minimize the shear stress acting across their long axis. Paracellular transport correlated with the level of this minimized shear, but transcellular transport was reduced uniformly by flow regardless of the shear profile. Copyright © 2017 the American Physiological Society.

Luminal flow regulates NO and O2− along the nephron

PubMed Central

Cabral, Pablo D.

2011-01-01

Urinary flow is not constant but in fact highly variable, altering the mechanical forces (shear stress, stretch, and pressure) exerted on the epithelial cells of the nephron as well as solute delivery. Nitric oxide (NO) and superoxide (O2−) play important roles in various processes within the kidney. Reductions in NO and increases in O2− lead to abnormal NaCl and water absorption and hypertension. In the last few years, luminal flow has been shown to be a regulator of NO and O2− production along the nephron. Increases in luminal flow enhance fluid, Na, and bicarbonate transport in the proximal tubule. However, we know of no reports directly addressing flow regulation of NO and O2− in this segment. In the thick ascending limb, flow-stimulated NO and O2− formation has been extensively studied. Luminal flow stimulates NO production by nitric oxide synthase type 3 and its translocation to the apical membrane in medullary thick ascending limbs. These effects are mediated by flow-induced shear stress. In contrast, flow-induced stretch and NaCl delivery stimulate O2− production by NADPH oxidase in this segment. The interaction between flow-induced NO and O2− is complex and involves more than one simply scavenging the other. Flow-induced NO prevents flow from increasing O2− production via cGMP-dependent protein kinase in thick ascending limbs. In macula densa cells, shear stress increases NO production and this requires that the primary cilia be intact. The role of luminal flow in NO and O2− production in the distal tubule is not known. In cultured inner medullary collecting duct cells, shear stress enhances nitrite accumulation, a measure of NO production. Although much progress has been made on this subject in the last few years, there are still many unanswered questions. PMID:21345976

Prediction of Flow Stress in Cadmium Using Constitutive Equation and Artificial Neural Network Approach

NASA Astrophysics Data System (ADS)

Sarkar, A.; Chakravartty, J. K.

2013-10-01

A model is developed to predict the constitutive flow behavior of cadmium during compression test using artificial neural network (ANN). The inputs of the neural network are strain, strain rate, and temperature, whereas flow stress is the output. Experimental data obtained from compression tests in the temperature range -30 to 70 °C, strain range 0.1 to 0.6, and strain rate range 10-3 to 1 s-1 are employed to develop the model. A three-layer feed-forward ANN is trained with Levenberg-Marquardt training algorithm. It has been shown that the developed ANN model can efficiently and accurately predict the deformation behavior of cadmium. This trained network could predict the flow stress better than a constitutive equation of the type.

Oscillatory flow past a slip cylindrical inclusion embedded in a Brinkman medium

NASA Astrophysics Data System (ADS)

Palaniappan, D.

2015-11-01

Transient flow past a circular cylinder embedded in a porous medium is studied based on Brinkman model with Navier slip conditions. Closed form analytic solution for the stream-function describing slow oscillatory flow around a solid cylindrical inclusion is obtained in the limit of low-Reynolds-number. The key parameters such as the frequency of oscillation λ, the permeability constant δ, and the slip coefficient ξ dictate the flow fields and physical quantities in the entire flow domain. Asymptotic steady-state analysis when δ --> 0 reveals the paradoxical behavior detected by Stokes. Local streamlines for small times demonstrate interesting flow patterns. Rapid transitions including flow separations and eddies are observed far away from the solid inclusion. Analytic expressions for the wall shear stress and the force acting on the cylinder are computed and compared with existing results. It is noted that the slip parameter in the range 0 <= ξ <= 0 . 5 has a significant effect in reducing the stress and force. In the limit of large permeability, Darcy (potential) flow is recovered outside a boundary layer. The results are of some interest in predicting maximum wall stress and pressure drop associated with biological models in fibrous media.

Experimental investigations of the time and flow-direction responses of shear-stress-sensitive liquid crystal coatings

NASA Technical Reports Server (NTRS)

Reda, Daniel C.; Muratore, Joseph J., Jr.; Heineck, James T.

1993-01-01

Time and flow-direction responses of shearstress-sensitive liquid crystal coatings were explored experimentally. For the time-response experiments, coatings were exposed to transient, compressible flows created during the startup and off-design operation of an injector-driven supersonic wind tunnel. Flow transients were visualized with a focusing Schlieren system and recorded with a 1000 frame/sec color video camera. Liquid crystal responses to these changing-shear environments were then recorded with the same video system, documenting color-play response times equal to, or faster than, the time interval between sequential frames (i.e., 1 millisecond). For the flow-direction experiments, a planar test surface was exposed to equal-magnitude and known-direction surface shear stresses generated by both normal and tangential subsonic jet-impingement flows. Under shear, the sense of the angular displacement of the liquid crystal dispersed (reflected) spectrum was found to be a function of the instantaneous direction of the applied shear. This technique thus renders dynamic flow reversals or flow divergences visible over entire test surfaces at image recording rates up to 1 KHz. Extensions of the technique to visualize relatively small changes in surface shear stress direction appear feasible.

Flow behavior and mobility of contaminated waste rock materials in the abandoned Imgi mine in Korea

NASA Astrophysics Data System (ADS)

Jeong, S. W.; Wu, Y.-H.; Cho, Y. C.; Ji, S. W.

2018-01-01

Incomplete mine reclamation can cause ecological and environmental impacts. This paper focuses on the geotechnical and rheological characteristics of waste rock materials, which are mainly composed of sand-size particles, potentially resulting in mass movement (e.g., slide or flow) and extensive acid mine drainage. To examine the potential for contaminant mobilization resulting from physicochemical processes in abandoned mines, a series of scenario-based debris flow simulations was conducted using Debris-2D to identify different hazard scenarios and volumes. The flow behavior of waste rock materials was examined using a ball-measuring rheometric apparatus, which can be adapted for large particle samples, such as debris flow. Bingham yield stresses determined in controlled shear rate mode were used as an input parameter in the debris flow modeling. The yield stresses ranged from 100 to 1000 Pa for shear rates ranging from 10- 5 to 102 s- 1. The results demonstrated that the lowest yield stress could result in high mobility of debris flow (e.g., runout distance > 700 m from the source area for 60 s); consequently, the material contaminants may easily reach the confluence of the Suyoung River through a mountain stream. When a fast slide or debris flow occurs at or near an abandoned mine area, it may result in extremely dynamic and destructive geomorphological changes. Even for the highest yield stress of debris flow simulation (i.e., τy = 2000 Pa), the released debris could flow into the mountain stream; therefore, people living near abandoned mines may become exposed to water pollution throughout the day. To maintain safety at and near abandoned mines, the physicochemical properties of waste materials should be monitored, and proper mitigation measures post-mining should be considered in terms of both their physical damage and chemical pollution potential.

The vertical structure of the circulation and dynamics in Hudson Shelf Valley

USGS Publications Warehouse

Lentz, Steven J.; Butman, Bradford; Harris, Courtney K.

2014-01-01

Hudson Shelf Valley is a 20–30 m deep, 5–10 km wide v-shaped submarine valley that extends across the Middle Atlantic Bight continental shelf. The valley provides a conduit for cross-shelf exchange via along-valley currents of 0.5 m s−1 or more. Current profile, pressure, and density observations collected during the winter of 1999–2000 are used to examine the vertical structure and dynamics of the flow. Near-bottom along-valley currents having times scales of a few days are driven by cross-shelf pressure gradients setup by wind stresses, with eastward (westward) winds driving onshore (offshore) flow within the valley. The along-valley momentum balance in the bottom boundary layer is predominantly between the pressure gradient and bottom stress because the valley bathymetry limits current veering. Above the bottom boundary layer, the flow veers toward an along-shelf (cross-valley) orientation and a geostrophic balance with some contribution from the wind stress (surface Ekman layer). The vertical structure and strength of the along-valley current depends on the magnitude and direction of the wind stress. During offshore flows driven by westward winds, the near-bottom stratification within the valley increases resulting in a thinner bottom boundary layer and weaker offshore currents. Conversely, during onshore flows driven by eastward winds the near-bottom stratification decreases resulting in a thicker bottom boundary layer and stronger onshore currents. Consequently, for wind stress magnitudes exceeding 0.1 N m−2, onshore along-valley transport associated with eastward wind stress exceeds the offshore transport associated with westward wind stress of the same magnitude.

Spatiotemporal evolution of hairpin eddies, Reynolds stress, and polymer torque in polymer drag-reduced turbulent channel flows.

PubMed

Kim, Kyoungyoun; Sureshkumar, Radhakrishna

2013-06-01

To study the influence of dynamic interactions between turbulent vortical structures and polymer stress on turbulent friction drag reduction, a series of simulations of channel flow is performed. We obtain self-consistent evolution of an initial eddy in the presence of polymer stresses by utilizing the finitely extensible nonlinear elastic-Peterlin (FENE-P) model. The initial eddy is extracted by the conditional averages for the second quadrant event from fully turbulent Newtonian flow, and the initial polymer conformation fields are given by the solutions of the FENE-P model equations corresponding to the mean shear flow in the Newtonian case. At a relatively low Weissenberg number We(τ) (=50), defined as the ratio of the polymer relaxation time to the wall time scale, the generation of new vortices is inhibited by polymer-induced countertorques. Thus fewer vortices are generated in the buffer layer. However, the head of the primary hairpin is unaffected by the polymer stress. At larger We(τ) values (≥100), the hairpin head becomes weaker and vortex autogeneration and Reynolds stress growth are almost entirely suppressed. The temporal evolution of the vortex strength and polymer torque magnitude reveals that polymer extension by the vortical motion results in a polymer torque that increases in magnitude with time until a maximum value is reached over a time scale comparable to the polymer relaxation time. The polymer torque retards the vortical motion and Reynolds stress production, which in turn weakens flow-induced chain extension and torque itself. An analysis of the vortex time scales reveals that with increasing We(τ), vortical motions associated with a broader range of time scales are affected by the polymer stress. This is qualitatively consistent with Lumley's time criterion for the onset of drag reduction.

New views of granular mass flows

USGS Publications Warehouse

Iverson, R.M.; Vallance, J.W.

2001-01-01

Concentrated grain-fluid mixtures in rock avalanches, debris flows, and pyroclastic flows do not behave as simple materials with fixed rheologies. Instead, rheology evolves as mixture agitation, grain concentration, and fluid-pressure change during flow initiation, transit, and deposition. Throughout a flow, however, normal forces on planes parallel to the free upper surface approximately balance the weight of the superincumbent mixture, and the Coulomb friction rule describes bulk intergranular shear stresses on such planes. Pore-fluid pressure can temporarily or locally enhance mixture mobility by reducing Coulomb friction and transferring shear stress to the fluid phase. Initial conditions, boundary conditions, and grain comminution and sorting can influence pore-fluid pressures and cause variations in flow dynamics and deposits.

Drought stress alters the concentration of wood terpenoids in Scots pine and Norway spruce seedlings.

PubMed

Turtola, Satu; Manninen, Anne-Marja; Rikala, Risto; Kainulainen, Pirjo

2003-09-01

Drought is known to have an impact on the resistance of conifers to various pests, for example, by affecting resin flow in trees. Little is known, however, about the quantitative and qualitative changes in resin when trees are growing in low moisture conditions. We exposed Scots pine (Pinus sylvestris L.) and Norway spruce (Picea abies (L.) Karst.) seedlings to medium and severe drought stress for two growing seasons and analyzed the monoterpenes and resin acids in the main stem wood after two years of treatment. In addition to secondary chemistry, we measured the level of nutrients in the needles and the growth response of seedlings. After the first year of treatment, drought stress did not affect the growth of seedlings, but in the second year, shoot growth was retarded, especially in Scots pine. In both conifer species, severe drought increased the concentrations of several individual monoterpenes and resin acids. Total monoterpenes and resin acids were 39 and 32% higher in severe drought-treated Scots pine seedlings than in the controls, and 35 and 45% higher in Norway spruce seedlings. In Scots pine needles, the concentrations of nitrogen and phosphorus increased, while magnesium and calcium decreased compared to controls. In Norway spruce needles, nutrient concentrations were not affected. The results suggest that drought stress substantially affects both the growth of conifers and the chemical quality of the wood. We discuss the potential trade-off in growth and defense of small conifer seedlings.

Stress tracking in thin bars by eigenstrain actuation

NASA Astrophysics Data System (ADS)

Schoeftner, J.; Irschik, H.

2016-11-01

This contribution focuses on stress tracking in slender structures. The axial stress distribution of a linear elastic bar is investigated, in particular, we seek for an answer to the following question: in which manner do we have to distribute eigenstrains, such that the axial stress in a bar is equal to a certain desired stress distribution, despite external forces or support excitations are present? In order to track a certain time- and space-dependent stress function, smart actuators, such as piezoelectric actuators, are needed to realize eigenstrains. Based on the equation of motion and the constitutive relation, which relate stress, strain, displacement and eigenstrains, an analytical solution for the stress tracking problem is derived. The starting point for the derivation of a solution for the stress tracking problem is a semi-positive definite integral depending on the error stress which is the difference between the actual stress and the desired stress. Our derived stress tracking theory is verified by two examples: first, a clamped-free bar which is harmonically excited is investigated. It is shown under which circumstances the axial stress vanishes at every location and at every time instant. The second example is a support-excited bar with end mass, where a desired stress profile is prescribed.

Static charge outside chamber induces dielectric breakdown of solid-state nanopore membranes

NASA Astrophysics Data System (ADS)

Matsui, Kazuma; Goto, Yusuke; Yanagi, Itaru; Yanagawa, Yoshimitsu; Ishige, Yu; Takeda, Ken-ichi

2018-04-01

Reducing device capacitance is effective for decreasing current noise observed in a solid-state nanopore-based DNA sequencer. On the other hand, we have recently found that voltage stress causes pinhole-like defects in such low-capacitance devices. The origin of voltage stress, however, has not been determined. In this research, we identified that a dominant origin is static charge on the outer surface of a flow cell. Even though the outer surface was not in direct contact with electrolytes in the flow cell, the charge induces high voltage stress on a membrane according to the capacitance coupling ratio of the flow cell to the membrane.

Numerical study of a separating and reattaching flow by using Reynolds-stress tubulence closure

NASA Technical Reports Server (NTRS)

Amano, R. S.; Goel, P.

1983-01-01

The numerical study of the Reynolds-stress turbulence closure for separating, reattaching, recirculating and redeveloping flow is summarized. The calculations were made for two different closure models of pressure - strain correlation. The results were compared with the experimental data. Furthermore, these results were compared with the computations made by using the one layer and three layer treatment of k-epsilon turbulence model which were developed. Generally the computations by the Reynolds-stress model show better results than those by the k-epsilon model, in particular, some improvement was noticed in the redeveloping region of the separating and reattaching flow in a pipe with sudden expansion.

Experimental analysis of the vorticity and turbulent flow dynamics of a pitching airfoil at realistic flight (helicopter) conditions

NASA Astrophysics Data System (ADS)

Sahoo, Dipankar

Improved basic understanding, predictability, and controllability of vortex-dominated and unsteady aerodynamic flows are important in enhancement of the performance of next generation helicopters. The primary objective of this research project was improved understanding of the fundamental vorticity and turbulent flow physics for a dynamically stalling airfoil at realistic helicopter flight conditions. An experimental program was performed on a large-scale (C = 0.45 m) dynamically pitching NACA 0012 wing operating in the Texas A&M University large-scale wind tunnel. High-resolution particle image velocimetry data were acquired on the first 10-15% of the wing. Six test cases were examined including the unsteady (k>0) and steady (k=0) conditions. The relevant mechanical, shear and turbulent time-scales were all of comparable magnitude, which indicated that the flow was in a state of mechanical non-equilibrium, and the expected flow separation and reattachment hystersis was observed. Analyses of the databases provided new insights into the leading-edge Reynolds stress structure and the turbulent transport processes. Both of which were previously uncharacterized. During the upstroke motion of the wing, a bubble structure formed in the leading-edge Reynolds shear stress. The size of the bubble increased with increasing angle-of-attack before being diffused into a shear layer at full separation. The turbulent transport analyses indicated that the axial stress production was positive, where the transverse production was negative. This implied that axial turbulent stresses were being produced from the axial component of the mean flow. A significant portion of the energy was transferred to the transverse stress through the pressure-strain redistribution, and then back to the transverse mean flow through the negative transverse production. An opposite trend was observed further downstream of this region.

Flow and volume dependence of rat airway resistance during constant flow inflation and deflation.

PubMed

Rubini, Alessandro; Carniel, Emanuele Luigi; Parmagnani, Andrea; Natali, Arturo Nicola

2011-12-01

The aim of this study was to measure the flow and volume dependence of both the ohmic and the viscoelastic pressure dissipations of the normal rat respiratory system separately during inflation and deflation. The study was conducted in the Respiratory Physiology Laboratory in our institution. Measurements were obtained for Seven albino Wistar rats of both sexes by using the flow interruption method during constant flow inflations and deflations. Measurements included anesthesia induction, tracheostomy and positioning of a tracheal cannula, positive pressure ventilation, constant flow respiratory system inflations and deflations at two different volumes and flows. The ohmic resistance exhibited volume and flow dependence, decreasing with lung volume and increasing with flow rate, during both inflation and deflation. The stress relaxation-related viscoelastic resistance also exhibited volume and flow dependence. It decreased with the flow rate at a constant lung volume during both inflation and deflation, but exhibited a different behavior with the lung volume at a constant flow rate (i.e., increased during inflations and decreased during deflations). Thus, stress relaxation in the rat lungs exhibited a hysteretic behavior. The observed flow and volume dependence of respiratory system resistance may be predicted by an equation derived from a model of the respiratory system that consists of two distinct compartments. The equation agrees well with the experimental data and indicates that the loading time is the critical parameter on which stress relaxation depends, during both lung inflation and deflation.

Gradient flows without blow-up for Lefschetz thimbles

DOE PAGES

Tanizaki, Yuya; Nishimura, Hiromichi; Verbaarschot, Jacobus J. M.

2017-10-16

We propose new gradient flows that define Lefschetz thimbles and do not blow up in a finite flow time. Here, we study analytic properties of these gradient flows, and confirm them by numerical tests in simple examples.

Dynamics of Deformable Active Particles under External Flow Field

NASA Astrophysics Data System (ADS)

Tarama, Mitsusuke

2017-10-01

In most practical situations, active particles are affected by their environment, for example, by a chemical concentration gradient, light intensity, gravity, or confinement. In particular, the effect of an external flow field is important for particles swimming in a solvent fluid. For deformable active particles such as self-propelled liquid droplets and active vesicles, as well as microorganisms such as euglenas and neutrophils, a general description has been developed by focusing on shape deformation. In this review, we present our recent studies concerning the dynamics of a single active deformable particle under an external flow field. First, a set of model equations of active deformable particles including the effect of a general external flow is introduced. Then, the dynamics under two specific flow profiles is discussed: a linear shear flow, as the simplest example, and a swirl flow. In the latter case, the scattering dynamics of the active deformable particles by the swirl flow is also considered.

The least-squares finite element method for low-mach-number compressible viscous flows

NASA Technical Reports Server (NTRS)

Yu, Sheng-Tao

1994-01-01

The present paper reports the development of the Least-Squares Finite Element Method (LSFEM) for simulating compressible viscous flows at low Mach numbers in which the incompressible flows pose as an extreme. Conventional approach requires special treatments for low-speed flows calculations: finite difference and finite volume methods are based on the use of the staggered grid or the preconditioning technique; and, finite element methods rely on the mixed method and the operator-splitting method. In this paper, however, we show that such difficulty does not exist for the LSFEM and no special treatment is needed. The LSFEM always leads to a symmetric, positive-definite matrix through which the compressible flow equations can be effectively solved. Two numerical examples are included to demonstrate the method: first, driven cavity flows at various Reynolds numbers; and, buoyancy-driven flows with significant density variation. Both examples are calculated by using full compressible flow equations.

Effect of exercise on hemodynamic conditions in the abdominal aorta.

PubMed

Taylor, C A; Hughes, T J; Zarins, C K

1999-06-01

The beneficial effect of exercise in the retardation of the progression of cardiovascular disease is hypothesized to be caused, at least in part, by the elimination of adverse hemodynamic conditions, including flow recirculation and low wall shear stress. In vitro and in vivo investigations have provided qualitative and limited quantitative information on flow patterns in the abdominal aorta and on the effect of exercise on the elimination of adverse hemodynamic conditions. We used computational fluid mechanics methods to examine the effects of simulated exercise on hemodynamic conditions in an idealized model of the human abdominal aorta. A three-dimensional computer model of a healthy human abdominal aorta was created to simulate pulsatile aortic blood flow under conditions of rest and graded exercise. Flow velocity patterns and wall shear stress were computed in the lesion-prone infrarenal aorta, and the effects of exercise were determined. A recirculation zone was observed to form along the posterior wall of the aorta immediately distal to the renal vessels under resting conditions. Low time-averaged wall shear stress was present in this location, along the posterior wall opposite the superior mesenteric artery and along the anterior wall between the superior and inferior mesenteric arteries. Shear stress temporal oscillations, as measured with an oscillatory shear index, were elevated in these regions. Under simulated light exercise conditions, a region of low wall shear stress and high oscillatory shear index remained along the posterior wall immediately distal to the renal arteries. Under simulated moderate exercise conditions, all the regions of low wall shear stress and high oscillatory shear index were eliminated. This numeric investigation provided detailed quantitative data on the effect of exercise on hemodynamic conditions in the abdominal aorta. Our results indicated that moderate levels of lower limb exercise are necessary to eliminate the flow reversal and regions of low wall shear stress in the abdominal aorta that exist under resting conditions. The lack of flow reversal and increased wall shear stress during exercise suggest a mechanism by which exercise may promote arterial health, namely with the elimination of adverse hemodynamic conditions.

Computation of confined coflow jets with three turbulence models

NASA Technical Reports Server (NTRS)

Zhu, J.; Shih, T. H.

1993-01-01

A numerical study of confined jets in a cylindrical duct is carried out to examine the performance of two recently proposed turbulence models: an RNG-based K-epsilon model and a realizable Reynolds stress algebraic equation model. The former is of the same form as the standard K-epsilon model but has different model coefficients. The latter uses an explicit quadratic stress-strain relationship to model the turbulent stresses and is capable of ensuring the positivity of each turbulent normal stress. The flow considered involves recirculation with unfixed separation and reattachment points and severe adverse pressure gradients, thereby providing a valuable test of the predictive capability of the models for complex flows. Calculations are performed with a finite-volume procedure. Numerical credibility of the solutions is ensured by using second-order accurate differencing schemes and sufficiently fine grids. Calculations with the standard K-epsilon model are also made for comparison. Detailed comparisons with experiments show that the realizable Reynolds stress algebraic equation model consistently works better than does the standard K-epsilon model in capturing the essential flow features, while the RNG-based K-epsilon model does not seem to give improvements over the standard K-epsilon model under the flow conditions considered.

Numerical simulation of fluid flow in a rotational bioreactor

NASA Astrophysics Data System (ADS)

Ganimedov, V. L.; Papaeva, E. O.; Maslov, N. A.; Larionov, P. M.

2017-10-01

Application of scaffold technology for the problem of bone tissue regeneration has great prospects in modern medicine. The influence of fluid shear stress on stem cells cultivation and its differentiation into osteoblasts is the subject of intensive research. Mathematical modeling of fluid flow in bioreactor allowed us to determine the structure of flow and estimate the level of mechanical stress on cells. The series of computations for different rotation frequencies (0.083, 0.124, 0.167, 0.2 and 0.233 Hz) was performed for the laminar flow regime approximation. It was shown that the Taylor vortices in the gap between the cylinders qualitatively change the distribution of static pressure and shear stress in the region of vortices connection. It was shown that an increase in the rotation frequency leads to an increase of the unevenness in distribution of the above mentioned functions. The obtained shear stress and static pressure dependence on the rotational frequency make it possible to choose the operating mode of the reactor depending on the provided requirements. It was shown that in the range of rotation frequencies chosen in this work (0.083 < f < 0.233 Hz), the shear stress does not exceed the known literature data (0.002 - 0.1 Pa).

Test-Retest Repeatability of Myocardial Blood Flow Measurements using Rubidium-82 Positron Emission Tomography

NASA Astrophysics Data System (ADS)

Efseaff, Matthew

Rubidium-82 positron emission tomography (PET) imaging has been proposed for routine myocardial blood flow (MBF) quantification. Few studies have investigated the test-retest repeatability of this method. Same-day repeatability of rest MBF imaging was optimized with a highly automated analysis program using image-derived input functions and a dual spillover correction (SOC). The effects of heterogeneous tracer infusion profiles and subject hemodynamics on test-retest repeatability were investigated at rest and during hyperemic stress. Factors affecting rest MBF repeatability included gender, suspected coronary artery disease, and dual SOC (p < 0.001). The best repeatability coefficient for same-day rest MBF was 0.20 mL/min/g using a six-minute scan-time, iterative reconstruction, dual SOC, resting rate-pressure-product (RPP) adjustment, and a left atrium image-derived input function. The serial study repeatabilities of the optimized protocol in subjects with homogeneous RPPs and tracer infusion profiles was 0.19 and 0.53 mL/min/g at rest and stress, and 0.95 for stress / rest myocardial flow reserve (MFR). Subjects with heterogeneous tracer infusion profiles and hemodynamic conditions had significantly less repeatable MBF measurements at rest, stress, and stress/rest flow reserve (p < 0.05).

Tensile properties and flow behavior analysis of modified 9Cr-1Mo steel clad tube material

NASA Astrophysics Data System (ADS)

Singh, Kanwarjeet; Latha, S.; Nandagopal, M.; Mathew, M. D.; Laha, K.; Jayakumar, T.

2014-11-01

The tensile properties and flow behavior of modified 9Cr-1Mo steel clad tube have been investigated in the framework of various constitutive equations for a wide range of temperatures (300-923 K) and strain rates (3 × 10-3 s-1, 3 × 10-4 s-1 and 3 × 10-5 s-1). The tensile flow behavior of modified 9Cr-1Mo steel clad tube was most accurately described by Voce equation. The variation of instantaneous work hardening rate (θ = dσ/dε) and σθ with stress (σ) indicated two stage behavior characterized by rapid decrease at low stresses (transient stage) followed by a gradual decrease in high stresses (Stage III). The variation of work hardening parameters and work hardening rate in terms of θ vs. σ and σθ vs. σ with temperature exhibited three distinct regimes. Rapid decrease in flow stress and work hardening parameters and rapid shift of θ vs. σ and σθ vs. σ towards low stresses with increase in temperature indicated dynamic recovery at high temperatures. Tensile properties of the material have been best predicted from Voce equation.

Numerical simulation of the groundwater-flow system of the Kitsap Peninsula, west-central Washington

USGS Publications Warehouse

Frans, Lonna M.; Olsen, Theresa D.

2016-05-05

A groundwater-flow model was developed to improve understanding of water resources on the Kitsap Peninsula. The Kitsap Peninsula is in the Puget Sound lowland of west-central Washington, is bounded by Puget Sound on the east and by Hood Canal on the west, and covers an area of about 575 square miles. The peninsula encompasses all of Kitsap County, Mason County north of Hood Canal, and part of Pierce County west of Puget Sound. The peninsula is surrounded by saltwater, and the hydrologic setting is similar to that of an island. The study area is underlain by a thick sequence of unconsolidated glacial and interglacial deposits that overlie sedimentary and volcanic bedrock units that crop out in the central part of the study area. Twelve hydrogeologic units consisting of aquifers, confining units, and an underlying bedrock unit form the basis of the groundwater-flow model.Groundwater flow on the Kitsap Peninsula was simulated using the groundwater-flow model, MODFLOW‑NWT. The finite difference model grid comprises 536 rows, 362 columns, and 14 layers. Each model cell has a horizontal dimension of 500 by 500 feet, and the model contains a total of 1,227,772 active cells. Groundwater flow was simulated for transient conditions. Transient conditions were simulated for January 1985–December 2012 using annual stress periods for 1985–2004 and monthly stress periods for 2005–2012. During model calibration, variables were adjusted within probable ranges to minimize differences between measured and simulated groundwater levels and stream baseflows. As calibrated to transient conditions, the model has a standard deviation for heads and flows of 47.04 feet and 2.46 cubic feet per second, respectively.Simulated inflow to the model area for the 2005–2012 period from precipitation and secondary recharge was 585,323 acre-feet per year (acre-ft/yr) (93 percent of total simulated inflow ignoring changes in storage), and simulated inflow from stream and lake leakage was 43,905 acre-ft/yr (7 percent of total simulated inflow). Simulated outflow from the model primarily was through discharge to streams, lakes, springs, seeps, and Puget Sound (594,595 acre-ft/yr; 95 percent of total simulated outflow excluding changes in storage) and through withdrawals from wells (30,761 acre-ft/yr; 5 percent of total simulated outflow excluding changes in storage).Six scenarios were formulated with input from project stakeholders and were simulated using the calibrated model to provide representative examples of how the model could be used to evaluate the effects on water levels and stream baseflows of potential changes in groundwater withdrawals, in consumptive use, and in recharge. These included simulations of a steady-state system, no-pumping and return flows, 15-percent increase in current withdrawals in all wells, 80-percent decrease in outdoor water to simulate effects of conservation efforts, 15-percent decrease in recharge from precipitation to simulate a drought, and particle tracking to determine flow paths.Changes in water-level altitudes and baseflow amounts vary depending on the stress applied to the system in these various scenarios. Reducing recharge by 15 percent between 2005 and 2012 had the largest effect, with water-level altitudes declining throughout the model domain and baseflow amounts decreasing by as much as 18 percent compared to baseline conditions. Changes in pumping volumes had a smaller effect on the model. Removing all pumping and resulting return flows caused increased water-level altitudes in many areas and increased baseflow amounts of between 1 and 3 percent.

Embrittlement and Flow Localization in Reactor Structural Materials

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xianglin Wu; Xiao Pan; James Stubbins

2006-10-06

Many reactor components and structural members are made from metal alloys due, in large part, to their strength and ability to resist brittle fracture by plastic deformation. However, brittle fracture can occur when structural material cannot undergo extensive, or even limited, plastic deformation due to irradiation exposure. Certain irradiation conditions lead to the development of a damage microstructure where plastic flow is limited to very small volumes or regions of material, as opposed to the general plastic flow in unexposed materials. This process is referred to as flow localization or plastic instability. The true stress at the onset of neckingmore » is a constant regardless of the irradiation level. It is called 'critical stress' and this critical stress has strong temperature dependence. Interrupted tensile testes of 316L SS have been performed to investigate the microstructure evolution and competing mechanism between mechanic twinning and planar slip which are believed to be the controlling mechanism for flow localization. Deformation twinning is the major contribution of strain hardening and good ductility for low temperatures, and the activation of twinning system is determined by the critical twinning stress. Phases transform and texture analyses are also discussed in this study. Finite element analysis is carried out to complement the microstructural analysis and for the prediction of materaials performance with and without stress concentration and irradiation.« less

Modeling of Turbulent Swirling Flows

NASA Technical Reports Server (NTRS)

Shih, Tsan-Hsing; Zhu, Jiang; Liou, William; Chen, Kuo-Huey; Liu, Nan-Suey; Lumley, John L.

1997-01-01

Aircraft engine combustors generally involve turbulent swirling flows in order to enhance fuel-air mixing and flame stabilization. It has long been recognized that eddy viscosity turbulence models are unable to appropriately model swirling flows. Therefore, it has been suggested that, for the modeling of these flows, a second order closure scheme should be considered because of its ability in the modeling of rotational and curvature effects. However, this scheme will require solution of many complicated second moment transport equations (six Reynolds stresses plus other scalar fluxes and variances), which is a difficult task for any CFD implementations. Also, this scheme will require a large amount of computer resources for a general combustor swirling flow. This report is devoted to the development of a cubic Reynolds stress-strain model for turbulent swirling flows, and was inspired by the work of Launder's group at UMIST. Using this type of model, one only needs to solve two turbulence equations, one for the turbulent kinetic energy k and the other for the dissipation rate epsilon. The cubic model developed in this report is based on a general Reynolds stress-strain relationship. Two flows have been chosen for model evaluation. One is a fully developed rotating pipe flow, and the other is a more complex flow with swirl and recirculation.

Spontaneous electric current flow during deformation of non-piezoelectric marble samples: an indicator of stress state?

NASA Astrophysics Data System (ADS)

Cartwright-Taylor, A. L.; Sammonds, P. R.; Vallianatos, F.

2016-12-01

We recorded spontaneous electric current flow in non-piezoelectric Carrara marble samples during triaxial deformation. Mechanical data, ultrasonic velocities and acoustic emissions were acquired simultaneously with electric current to constrain the relationship between electric current flow, differential stress and damage. Under strain-controlled loading, spontaneous electric current signals (nA) were generated and sustained under all conditions tested. In dry samples, a detectable electric current arises only during dilatancy and is correlated with the damage induced by microcracking. Signal variations with confining pressure correspond to microcrack suppression, while variations with strain rate are associated with time-dependent differences in deformation mechanism across the brittle to semi-brittle transition. In the brittle regime, the signal exhibits a precursory change as damage localises and the stress drop accelerates towards failure. This change is particularly distinct at dynamic strain rates. Similar changes are seen in the semi-brittle regime although the signal is more oscillatory in nature. Current flow in dry samples is proportional to stress within 90% of peak stress. In fluid-saturated samples proportionality holds from 40% peak stress, with a significant increase in the rate of current production from 90% peak stress associated with fluid flow during dilatancy. This direct relationship demonstrates that electric current could be used as a proxy for stress, indicating when the rock is reaching the limit of its strength. The experimental power law relationship between electric current and strain rate, which mirrors the power-law creep equation, supports this observation. High-frequency fluctuations of electric current are not normally distributed - they exhibit `heavy-tails'. We model these distributions with q-Gaussian statistics and evolution of the q-parameter during deformation reveals a two-stage precursory anomaly prior to sample failure, consistent with the acoustic emissions b-value and stress intensity evolution as modelled from fracture mechanics. Our findings support the idea that electric currents in the crust can be generated purely from solid state fracture processes and that these currents may reflect the stress state within the damaged rock.

Coordination of contractility, adhesion and flow in migrating Physarum amoebae.

PubMed

Lewis, Owen L; Zhang, Shun; Guy, Robert D; del Álamo, Juan C

2015-05-06

This work examines the relationship between spatio-temporal coordination of intracellular flow and traction stress and the speed of amoeboid locomotion of microplasmodia of Physarum polycephalum. We simultaneously perform particle image velocimetry and traction stress microscopy to measure the velocity of cytoplasmic flow and the stresses applied to the substrate by migrating Physarum microamoebae. In parallel, we develop a mathematical model of a motile cell which includes forces from the viscous cytosol, a poro-elastic, contractile cytoskeleton and adhesive interactions with the substrate. Our experiments show that flow and traction stress exhibit back-to-front-directed waves with a distinct phase difference. The model demonstrates that the direction and speed of locomotion are determined by this coordination between contraction, flow and adhesion. Using the model, we identify forms of coordination that generate model predictions consistent with experiments. We demonstrate that this coordination produces near optimal migration speed and is insensitive to heterogeneity in substrate adhesiveness. While it is generally thought that amoeboid motility is robust to changes in extracellular geometry and the nature of extracellular adhesion, our results demonstrate that coordination of adhesive forces is essential to producing robust migration. © 2015 The Author(s) Published by the Royal Society. All rights reserved.

Aerodynamic performance of a fan stage utilizing Variable Inlet Guide Vanes (VIGVs) for thrust modulation. [subsonic V/STOL aircraft

NASA Technical Reports Server (NTRS)

Woollett, R. R.

1983-01-01

An experimental research program was conducted in the Lewis Research Center's 9x15-foot (2.74x4.57 m) low speed wind tunnel to evaluate the aerodynamic performance of an inlet and fan system with variable inlet guide vanes (VIGVs) for use on a subsonic V/STOL aircraft. At high VIGV blade angles (lower weight flow and thrust levels), the fan stage was stalled over a major portion of its radius. In spite of the stall, fan blade stresses only exceeded the limits at the most extreme flow conditions. It was found that inlet flow separation does not necessarily lead to poor inlet performance or adverse fan operating conditions. Generally speaking, separated inlet flow did not adversely affect the fan blade stress levels. There were some cases, however, at high VIGV angles and high inlet angles-of-attack where excessive blade stress levels were encountered. An evaluation term made up of the product of the distortion parameter, K alpha, the weight flow and the fan pressure ratio minus one, was found to correlate quite well with the observed blade stress results.

Aerodynamic performance of a fan stage utilizing variable inlet guide vanes (VIGV's) for thrust modulation. [subsonic V/STOL aircraft

NASA Technical Reports Server (NTRS)

Woollett, R. R.

1983-01-01

An experimental research program was conducted in the Lewis Research Center's 9 x 15-foot (2.74 x 4.57 m) low speed wind tunnel to evaluate the aerodynamic performance of an inlet and fan system with variable inlet guide vanes (VIGVs) for use on a subsonic V/STOL aircraft. At high VIGV blade angles (lower weight flow and thrust levels), the fan stage was stalled over a major portion of its radius. In spite of the stall, fan blade stresses only exceeded the limits at the most extreme flow conditions. It was found that inlet flow separation does not necessarily lead to poor inlet performance or adverse fan operating conditions. Generally speaking, separated inlet flow did not adversely affect the fan blade stress levels. There were some cases, however, at high VIGV angles and high inlet angles-of-attack where excessive blade stress levels were encountered. An evaluation term made up of the product of the distortion parameter, K alpha, the weight flow and the fan pressure ratio minus one, was found to correlate quite well with the observed blade stress results. Previously announced in STAR as N83-27957

Abdominal Aortic Hemodynamics in Intermittent Claudication Patients at Rest and During Dynamic Pedaling Exercise

PubMed Central

Cheng, Christopher P.; Taylor, Charles A.; Dalman, Ronald L.

2015-01-01

Introduction Lower extremity exercise has been shown to eliminate adverse hemodynamics conditions, such as low and oscillating blood flow and wall shear stress, in the abdominal aortas of healthy young and older adults. Methods We use cine phase-contrast magnetic resonance imaging and a custom MRI-compatible exercise cycle to quantify hemodynamic changes due to pedaling exercise in patients diagnosed with intermittent claudication. Results and Conclusions With only an average heart increase of 35±18% and exercise workload of 36±16 Watts, the patients experienced approximately 3- and 6-fold increases in blood flow, and 4- and 16-fold increases in wall shear stress at the supraceliac and infrarenal aortic locations, respectively. Also, all oscillations in flow and shear stress at rest were eliminated with exercise. Claudication patients experience 3 to 4-fold lower oscillations in flow and shear stress at rest as compared to healthy age-matched controls, likely due to reduced distal arterial compliance as a result of distal atherosclerosis. The magnitude of flow and shear oscillatory indices may be good indicators of distal arterial compliance and health, and may provide predictive power for the efficacy of focal interventions. PMID:26315797

Poiseuille flow of soft glasses in narrow channels: from quiescence to steady state.

PubMed

Chaudhuri, Pinaki; Horbach, Jürgen

2014-10-01

Using numerical simulations, the onset of Poiseuille flow in a confined soft glass is investigated. Starting from the quiescent state, steady flow sets in at a time scale which increases with a decrease in applied forcing. At this onset time scale, a rapid transition occurs via the simultaneous fluidization of regions having different local stresses. In the absence of steady flow at long times, creep is observed even in regions where the local stress is larger than the bulk yielding threshold. Finally, we show that the time scale to attain steady flow depends strongly on the history of the initial state.

Optimal Adenosine Stress for Maximum Stress Perfusion, Coronary Flow Reserve, and Pixel Distribution of Coronary Flow Capacity by Kolmogorov-Smirnov Analysis.

PubMed

Kitkungvan, Danai; Lai, Dejian; Zhu, Hongjian; Roby, Amanda E; Johnson, Nils P; Steptoe, Derek D; Patel, Monica B; Kirkeeide, Richard; Gould, K Lance

2017-02-01

Different adenosine stress imaging protocols have not been systemically validated for absolute myocardial perfusion and coronary flow reserve (CFR) by positron emission tomography, where submaximal stress precludes assessing physiological severity of coronary artery disease. In 127 volunteers, serial rest-stress positron emission tomography scans using rubidium-82 with various adenosine infusion protocols identified (1) the protocol with maximum stress perfusion and CFR, (2) test-retest precision in same subject, (3) stress perfusion and CFR after adenosine compared with dipyridamole, (4) heterogeneity of coronary flow capacity combining stress perfusion and CFR, and (5) potential relevance for patients with risk factors or coronary artery disease. The adenosine 6-minute infusion with rubidium-82 injection at 3 minutes caused CFR that was significantly 15.7% higher than the 4-minute adenosine infusion with rubidium-82 injection at 2 minutes and significantly more homogeneous by Kolmogorov-Smirnov analysis for histograms of 1344 pixel range of perfusion in paired positron emission tomographies. In a coronary artery disease cohort separate from volunteers of this study, compared with the 3/6-minute protocol, the 2/4-minute adenosine protocol would potentially have changed 332 of 1732 (19%) positron emission tomographies at low-risk physiological severity CFR ≥2.3 to CFR <2.0, thereby implying high-risk quantitative severity potentially appropriate for interventions but because of suboptimal stress of the 2/4 protocol in some patients. The 6-minute adenosine infusion with rubidium-82 activation at 3 minutes produced CFR that averaged 15.7% higher than that in the 2/4-minute protocol, thereby potentially providing essential information for personalized management in some patients. © 2017 American Heart Association, Inc.

Stress Conflation: Evidence from Sooke.

ERIC Educational Resources Information Center

Davis, Stuart

A comparison of the application of two current theories of stress to a particular stress pattern found in the Salish language Sooke is presented. Hammond's (1986) grid-like tree structure representation of stress is compared with Halle and Vergnaud's (1986) tree-like grid structure. Examples in the Australian language Maranungku show that, in…

77 FR 62417 - Annual Stress Test

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-15

... to perform stress tests. For example, one commenter recommended that covered banks be permitted to... that the annual stress tests required under the final rule will be only one component of the broader... stress test. The FDIC may require a covered bank to include one or more additional scenarios in its...

DETECTING FOREST STRESS AND DECLINE IN RESPONSE TO INCREASING RIVER FLOW IN SOUTHWEST FLORIDA, USA

EPA Science Inventory

Forest stress and decline resulting from increased river flows were investigated in Myakka River State Park (MRSP), Florida, USA. Since 1977, land-use changes around the upper Myakka River watershed have resulted in significant increases in water entering the river, which have...

Turbulent Boundary Layer on a Cylinder in Axial Flow

DTIC Science & Technology

1988-09-29

finding the wall shea stress. Finally, ft ;hould be noted that the wall shear stress can be found from the streamwrwise gradient of the mornsntum...somewhat butter collapse than inner scaling, suggesting that the outer flow affects events at the wall. By comparison, the burst frequency in a planar

Cardiovascular reflexes during rest and exercise modified by gravitational stresses

NASA Astrophysics Data System (ADS)

Bonde-petersen, Flemming

The hypotheses tested were whether variations in central venous pressure via the low pressure baroreceptors would take over or modify the arterial baroreceptor function, and further to which extent local and "whole body" hydrostatic stresses influence blood flow distribution. We investigated total forearm and skin blood flow (venous occlusion plethysmography and 133-Xe clearance) and cardiac output (rebreathing method) among other parameters. Hypo-and hypergravitational stresses were simulated by LBNP, LBPP, water immersion and lowering of the arm. The changes in flow distribution in the arm were ascribed to arterial baroreceptor function and not to low pressure baroreceptor activity. The enhancement of venous return during water immersion increased exercise tolerance during heat stress presumably due both to increased stroke volume and decreased venous pooling. The response to sustained handgrip exercise during LBNP and LBPP was not different from control measurements and the effects explained by arterial baroreceptor function. Application of exercise and local hydrostatic stresses in combination with gravitational stresses represent an interesting model for further study of the mechanisms behind the distribution of cardiac output to the peripheral organs.

A SPH elastic-viscoplastic model for granular flows and bed-load transport

NASA Astrophysics Data System (ADS)

Ghaïtanellis, Alex; Violeau, Damien; Ferrand, Martin; Abderrezzak, Kamal El Kadi; Leroy, Agnès; Joly, Antoine

2018-01-01

An elastic-viscoplastic model (Ulrich, 2013) is combined to a multi-phase SPH formulation (Hu and Adams, 2006; Ghaitanellis et al., 2015) to model granular flows and non-cohesive sediment transport. The soil is treated as a continuum exhibiting a viscoplastic behaviour. Thus, below a critical shear stress (i.e. the yield stress), the soil is assumed to behave as an isotropic linear-elastic solid. When the yield stress is exceeded, the soil flows and behaves as a shear-thinning fluid. A liquid-solid transition threshold based on the granular material properties is proposed, so as to make the model free of numerical parameter. The yield stress is obtained from Drucker-Prager criterion that requires an accurate computation of the effective stress in the soil. A novel method is proposed to compute the effective stress in SPH, solving a Laplace equation. The model is applied to a two-dimensional soil collapse (Bui et al., 2008) and a dam break over mobile beds (Spinewine and Zech, 2007). Results are compared with experimental data and a good agreement is obtained.

Microfluidic perfusion culture chip providing different strengths of shear stress for analysis of vascular endothelial function.

PubMed

Hattori, Koji; Munehira, Yoichi; Kobayashi, Hideki; Satoh, Taku; Sugiura, Shinji; Kanamori, Toshiyuki

2014-09-01

We developed a microfluidic perfusion cell culture chip that provides three different shear stress strengths and a large cell culture area for the analysis of vascular endothelial functions. The microfluidic network was composed of shallow flow-control channels of three different depths and deep cell culture channels. The flow-control channels with high fluidic resistances created shear stress strengths ranging from 1.0 to 10.0 dyn/cm(2) in the cell culture channels. The large surface area of the culture channels enabled cultivation of a large number (approximately 6.0 × 10(5)) of cells. We cultured human umbilical vein endothelial cells (HUVECs) and evaluated the changes in cellular morphology and gene expression in response to applied shear stress. The HUVECs were aligned in the direction of flow when exposed to a shear stress of 10.0 dyn/cm(2). Compared with conditions of no shear stress, endothelial nitric oxide synthase mRNA expression increased by 50% and thrombomodulin mRNA expression increased by 8-fold under a shear stress of 9.5 dyn/cm(2). Copyright © 2014 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

Aerodynamic Surface Stress Intermittency and Conditionally Averaged Turbulence Statistics

NASA Astrophysics Data System (ADS)

Anderson, W.

2015-12-01

Aeolian erosion of dry, flat, semi-arid landscapes is induced (and sustained) by kinetic energy fluxes in the aloft atmospheric surface layer. During saltation -- the mechanism responsible for surface fluxes of dust and sediment -- briefly suspended sediment grains undergo a ballistic trajectory before impacting and `splashing' smaller-diameter (dust) particles vertically. Conceptual models typically indicate that sediment flux, q (via saltation or drift), scales with imposed aerodynamic (basal) stress raised to some exponent, n, where n > 1. Since basal stress (in fully rough, inertia-dominated flows) scales with the incoming velocity squared, u^2, it follows that q ~ u^2n (where u is some relevant component of the above flow field, u(x,t)). Thus, even small (turbulent) deviations of u from its time-averaged value may play an enormously important role in aeolian activity on flat, dry landscapes. The importance of this argument is further augmented given that turbulence in the atmospheric surface layer exhibits maximum Reynolds stresses in the fluid immediately above the landscape. In order to illustrate the importance of surface stress intermittency, we have used conditional averaging predicated on aerodynamic surface stress during large-eddy simulation of atmospheric boundary layer flow over a flat landscape with momentum roughness length appropriate for the Llano Estacado in west Texas (a flat agricultural region that is notorious for dust transport). By using data from a field campaign to measure diurnal variability of aeolian activity and prevailing winds on the Llano Estacado, we have retrieved the threshold friction velocity (which can be used to compute threshold surface stress under the geostrophic balance with the Monin-Obukhov similarity theory). This averaging procedure provides an ensemble-mean visualization of flow structures responsible for erosion `events'. Preliminary evidence indicates that surface stress peaks are associated with the passage of inclined, high-momentum regions flanked by adjacent low-momentum regions. We will characterize geometric attributes of such structures and explore streamwise and vertical vorticity distribution within the conditionally averaged flow field.

Modelling and simulation of temperature and concentration dispersion in a couple stress nanofluid flow through stenotic tapered arteries

NASA Astrophysics Data System (ADS)

Ramana Reddy, J. V.; Srikanth, D.; Das, Samir K.

2017-08-01

A couple stress fluid model with the suspension of silver nanoparticles is proposed in order to investigate theoretically the natural convection of temperature and concentration. In particular, the flow is considered in an artery with an obstruction wherein the rheology of blood is taken as a couple stress fluid. The effects of the permeability of the stenosis and the treatment procedure involving a catheter are also considered in the model. The obtained non-linear momentum, temperature and concentration equations are solved using the homotopy perturbation method. Nanoparticles and the two viscosities of the couple stress fluid seem to play a significant role in the flow regime. The pressure drop, flow rate, resistance to the fluid flow and shear stress are computed and their effects are analyzed with respect to various fluids and geometric parameters. Convergence of the temperature and its dependency on the degree of deformation is effectively depicted. It is observed that the Nusselt number increases as the volume fraction increases. Hence magnification of molecular thermal dispersion can be achieved by increasing the nanoparticle concentration. It is also observed that concentration dispersion is greater for severe stenosis and it is maximum at the first extrema. The secondary flow of the axial velocity in the stenotic region is observed and is asymmetric in the tapered artery. The obtained results can be utilized in understanding the increase in heat transfer and enhancement of mass dispersion, which could be used for drug delivery in the treatment of stenotic conditions.

The effects of spatial inhomogeneities on flow through the endothelial surface layer.

PubMed

Leiderman, Karin M; Miller, Laura A; Fogelson, Aaron L

2008-05-21

Flow through the endothelial surface layer (the glycocalyx and adsorbed plasma proteins) plays an important but poorly understood role in cell signaling through a process known as mechanotransduction. Characterizing the flow rates and shear stresses throughout this layer is critical for understanding how flow-induced ionic currents, deformations of transmembrane proteins, and the convection of extracellular molecules signal biochemical events within the cell, including cytoskeletal rearrangements, gene activation, and the release of vasodilators. Previous mathematical models of flow through the endothelial surface layer are based upon the assumptions that the layer is of constant hydraulic permeability and constant height. These models also assume that the layer is continuous across the endothelium and that the layer extends into only a small portion of the vessel lumen. Results of these models predict that fluid shear stress is dissipated through the surface layer and is thus negligible near endothelial cell membranes. In this paper, such assumptions are removed, and the resultant flow rates and shear stresses through the layer are described. The endothelial surface layer is modeled as clumps of a Brinkman medium immersed in a Newtonian fluid. The width and spacing of each clump, hydraulic permeability, and fraction of the vessel lumen occupied by the layer are varied. The two-dimensional Navier-Stokes equations with an additional Brinkman resistance term are solved using a projection method. Several fluid shear stress transitions in which the stress at the membrane shifts from low to high values are described. These transitions could be significant to cell signaling since the endothelial surface layer is likely dynamic in its composition, density, and height.

The Role and Modeling of Dispersive Stresses

NASA Astrophysics Data System (ADS)

Shavit, U.; Moltchanov, S.

2012-12-01

Dispersive stresses represent momentum fluxes that are induced by the spatial heterogeneity of flow environments such as forest canopies, river vegetation and coral reefs. When deriving the average momentum equation for such flow environments, these dispersive stresses resemble the Reynolds stresses but instead of correlations of temporal fluctuations they represent correlations of spatial fluctuations. Surprisingly, these stresses are ignored in flow models and very few studies attempted to provide a physical interpretation, let alone a closure model. Typical arguments that justify such modeling are that these stresses are small and negligible; however, recent studies have shown that they may be important. In a recent study we showed that dispersive stresses at the inlet to obstructed region (made of glass cylinders) are larger than the Reynolds stresses and their contribution to the momentum balance is as important as the pressure and the drag forces. In this presentation we will try to explain what they are, provide some intuitive physical interoperation and show that closure models can be developed. Our results are based on highly detailed particle image velocimeter (PIV) measurements that were obtained inside a canopy model made of vertical thin glass plates. Forty nine vertical cross sections were obtained 1000 times generating a huge dataset of more than 250 million data points for each flow conditions. A careful spatial averaging procedure was developed and both temporal and spatial correlations were obtained. An order of magnitude analysis will be presented and the role of each of the terms in the momentum equation will be evaluated. It will be shown that the dispersive stresses are large and significant within the area of the canopy leading edge. Since dispersive stresses do not exist upstream from the canopy they are expected to grow once the flow enters the canopy. Our PIV data shows an initial fast growth up to about one length scale into the patch. Following this peak value the dispersive stresses decrease, reaching low and constant values further downstream. The actual distance of importance depends on the drag imposed by the canopy. The challenging task of studying dispersive stresses is the development of closure models. We will demonstrate a linear relationship between the normal dispersive stresses and the square of the double-average velocity. We will also show that the non-constant proportionality coefficient depends on the area of the wakes behind the obstacles. We will propose a simple formulation for this coefficient and will use our detailed PIV measurements to demonstrate the good agreement between the modeled and measured stresses, both at the entry region and in the fully-developed region.

Scaling, Microstructure and Dynamic Fracture

NASA Astrophysics Data System (ADS)

Minich, Roger W.; Kumar, Mukul; Schwarz, Adam; Cazamias, James

2006-07-01

The relationship between pullback velocity and impact velocity is studied for different microstructures in Cu. A size distribution of potential nucleation sites is derived under the conditions of an applied stochastic stress field. The size distribution depends on the amplitude of the stress fluctuations, which may be proportional to the flow stress thereby providing a connection between plastic flow and microvoid nucleation rate. The pullback velocity in turn depends on the nucleation rate resulting in a prediction for the relationship between pullback velocity and flow stress. The theory is compared to results from Cu on Cu gas-gun experiments (10-50 GPa) with different microstructures. The scaling law relating pullback velocity and impact velocity is incorporated into a 1D finite difference code and is shown to reproduce the experimental data with one adjustable parameter, the nucleation exponent, Γ.

Runge-Kutta method for wall shear stress of blood flow in stenosed artery

NASA Astrophysics Data System (ADS)

Awaludin, Izyan Syazana; Ahmad, Rokiah@Rozita

2014-06-01

A mathematical model of blood flow through stenotic artery is considered. A stenosis is defined as the partial occlusion of the blood vessels due to the accumulation of cholesterols, fats and the abnormal growth of tissue on the artery walls. The development of stenosis in the artery is one of the factors that cause problem in blood circulation system. This study was conducted to determine the wall shear stress of blood flow in stenosed artery. Modified mathematical model is used to analyze the relationship of the wall shear stress versus the length and height of stenosis. The existing models that have been created by previous researchers are solved using fourth order Runge-Kutta method. Numerical results show that the wall shear stress is proportionate to the length and height of stenosis.

Analysis of flow patterns in a patient-specific aortic dissection model.

PubMed

Cheng, Z; Tan, F P P; Riga, C V; Bicknell, C D; Hamady, M S; Gibbs, R G J; Wood, N B; Xu, X Y

2010-05-01

Aortic dissection is the most common acute catastrophic event affecting the thoracic aorta. The majority of patients presenting with an uncomplicated type B dissection are treated medically, but 25% of these patients develop subsequent aneurysmal dilatation of the thoracic aorta. This study aimed at gaining more detailed knowledge of the flow phenomena associated with this condition. Morphological features and flow patterns in a dissected aortic segment of a presurgery type B dissection patient were analyzed based on computed tomography images acquired from the patient. Computational simulations of blood flow in the patient-specific model were performed by employing a correlation-based transitional version of Menter's hybrid k-epsilon/k-omega shear stress transport turbulence model implemented in ANSYS CFX 11. Our results show that the dissected aorta is dominated by locally highly disturbed, and possibly turbulent, flow with strong recirculation. A significant proportion (about 80%) of the aortic flow enters the false lumen, which may further increase the dilatation of the aorta. High values of wall shear stress have been found around the tear on the true lumen wall, perhaps increasing the likelihood of expanding the tear. Turbulence intensity in the tear region reaches a maximum of 70% at midsystolic deceleration phase. Incorporating the non-Newtonian behavior of blood into the same transitional flow model has yielded a slightly lower peak wall shear stress and higher maximum turbulence intensity without causing discernible changes to the distribution patterns. Comparisons between the laminar and turbulent flow simulations show a qualitatively similar distribution of wall shear stress but a significantly higher magnitude with the transitional turbulence model.

Role of large-scale motions to turbulent inertia in turbulent pipe and channel flows

NASA Astrophysics Data System (ADS)

Hwang, Jinyul; Lee, Jin; Sung, Hyung Jin

2015-11-01

The role of large-scale motions (LSMs) to the turbulent inertia (TI) term (the wall-normal gradient of the Reynolds shear stress) is examined in turbulent pipe and channel flows at Reτ ~ 930 . The TI term in the mean momentum equation represents the net force of inertia exerted by the Reynolds shear stress. Although the turbulence statistics characterizing the internal turbulent flows are similar close to the wall, the TI term differs in the logarithmic region due to the different characteristics of LSMs (λx > 3 δ) . The contribution of the LSMs to the TI term and the Reynolds shear stress in the channel flow is larger than that in the pipe flow. The LSMs in the logarithmic region act like a mean momentum source (where TI >0) even the TI profile is negative above the peak of the Reynolds shear stress. The momentum sources carried by the LSMs are related to the low-speed regions elongated in the downstream, revealing that momentum source-like motions occur in the upstream position of the low-speed structure. The streamwise extent of this structure is relatively long in the channel flow, whereas the high-speed regions on the both sides of the low-speed region in the channel flow are shorter and weaker than those in the pipe flow. This work was supported by the Creative Research Initiatives (No. 2015-001828) program of the National Research Foundation of Korea (MSIP) and partially supported by KISTI under the Strategic Supercomputing Support Program.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tanizaki, Yuya; Nishimura, Hiromichi; Verbaarschot, Jacobus J. M.

We propose new gradient flows that define Lefschetz thimbles and do not blow up in a finite flow time. Here, we study analytic properties of these gradient flows, and confirm them by numerical tests in simple examples.

Stratigraphic Stacking of Deepmarine Channel Levee Turbidites: Scales of Cyclicity and their Origin. Examples from the Laingsburg Fm. (Karoo, South Africa) and the Rosario Fm. (Baja, Mexico)

NASA Astrophysics Data System (ADS)

Kane, I. A.; Hodgson, D.

2009-12-01

Thinning upwards of the turbidite beds that form deepmarine channel levees is a common motif reported from modern and recent levees on the seafloor, from subsurface examples, and from outcropping ancient examples. Because levees are thought to be built by deposition from turbidity currents superelevated over their channel form, the volume and style of overbank deposition are controlled primarily by the relationship between levee height (i.e., thalweg to crest) and flow thickness, determining the amount of overspill. Thus stratigraphic variability of turbidite thickness is explained by some change in either or both of those factors, which may arise autocyclicly or allocyclicly. Variation in the ratio of intra-channel and extra-channel deposition can be an autocyclic stratigraphic response, e.g., in bypass dominated systems, thalweg aggradation may be retarded with respect to levee aggradation, hence as levee relief increases, flows become more confined and, given a relatively narrow range of flow sizes, the volume of overbank flow and deposit thickness decrease with stratigraphic height. However, the same stratigraphic response of the levee may occur due to allocyclic flow magnitude variation, i.e., through decreasing flow magnitude. In both the autocyclic and allocyclic case the stratigraphic response of the levee may be one of thinning upwards, even if the overall system response may be one of progradation (autocyclic bypassing case) or retrogradation (allocyclic decreasing flow magnitude case), with entirely different connotations for sequence stratigraphic interpretation. Here we report examples of different scales of bed thickness cyclicity (both thickening and thinning upward cycles superimposed by smaller scale cycles) within levees of the Rosario Formation, Baja California, Mexico, and from the Laingsburg Formation, Karoo, South Africa, and, together with published examples, discuss criteria for the recognition, and drivers of, autocyclic and allocyclic bed thickness trends.

Perspective - Systematic study of Reynolds stress closure models in the computations of plane channel flows

NASA Technical Reports Server (NTRS)

Demuren, A. O.; Sarkar, S.

1993-01-01

The roles of pressure-strain and turbulent diffusion models in the numerical calculation of turbulent plane channel flows with second-moment closure models are investigated. Three turbulent diffusion and five pressure-strain models are utilized in the computations. The main characteristics of the mean flow and the turbulent fields are compared against experimental data. All the features of the mean flow are correctly predicted by all but one of the Reynolds stress closure models. The Reynolds stress anisotropies in the log layer are predicted to varying degrees of accuracy (good to fair) by the models. None of the models could predict correctly the extent of relaxation towards isotropy in the wake region near the center of the channel. Results from the directional numerical simulation are used to further clarify this behavior of the models.

Systematic study of Reynolds stress closure models in the computations of plane channel flows

NASA Technical Reports Server (NTRS)

Demuren, A. O.; Sarkar, S.

1992-01-01

The roles of pressure-strain and turbulent diffusion models in the numerical calculation of turbulent plane channel flows with second-moment closure models are investigated. Three turbulent diffusion and five pressure-strain models are utilized in the computations. The main characteristics of the mean flow and the turbulent fields are compared against experimental data. All the features of the mean flow are correctly predicted by all but one of the Reynolds stress closure models. The Reynolds stress anisotropies in the log layer are predicted to varying degrees of accuracy (good to fair) by the models. None of the models could predict correctly the extent of relaxation towards isotropy in the wake region near the center of the channel. Results from the directional numerical simulation are used to further clarify this behavior of the models.

Water stress from high-volume hydraulic fracturing potentially threatens aquatic biodiversity and ecosystem services in Arkansas, United States

USGS Publications Warehouse

Entrekin, Sally; Trainor, Anne; Saiers, James; Patterson, Lauren; Maloney, Kelly O.; Fargione, Joseph; Kiesecker, Joseph M.; Baruch-Mordo, Sharon; Konschnik, Katherine E.; Wiseman, Hannah; Nicot, Jean-Philippe; Ryan, Joseph N.

2018-01-01

Demand for high-volume, short duration water withdrawals could create water stress to aquatic organisms in Fayetteville Shale streams sourced for hydraulic fracturing fluids. We estimated potential water stress using permitted water withdrawal volumes and actual water withdrawals compared to monthly median, low, and high streamflows. Risk for biological stress was considered at 20% of long-term median and 10% of high- and low-flow thresholds. Future well build-out projections estimated potential for continued stress. Most water was permitted from small, free-flowing streams and “frack” ponds (dammed streams). Permitted 12-h pumping volumes exceeded median streamflow at 50% of withdrawal sites in June, when flows were low. Daily water usage, from operator disclosures, compared to median streamflow showed possible water stress in 7–51% of catchments from June–November, respectively. If 100% of produced water was recycled, per-well water use declined by 25%, reducing threshold exceedance by 10%. Future water stress was predicted to occur in fewer catchments important for drinking water and species of conservation concern due to the decline in new well installations and increased use of recycled water. Accessible and precise withdrawal and streamflow data are critical moving forward to assess and mitigate water stress in streams that experience high-volume withdrawals.

Water Stress from High-Volume Hydraulic Fracturing Potentially Threatens Aquatic Biodiversity and Ecosystem Services in Arkansas, United States.

PubMed

Entrekin, Sally; Trainor, Anne; Saiers, James; Patterson, Lauren; Maloney, Kelly; Fargione, Joseph; Kiesecker, Joseph; Baruch-Mordo, Sharon; Konschnik, Katherine; Wiseman, Hannah; Nicot, Jean-Philippe; Ryan, Joseph N

2018-02-20

Demand for high-volume, short duration water withdrawals could create water stress to aquatic organisms in Fayetteville Shale streams sourced for hydraulic fracturing fluids. We estimated potential water stress using permitted water withdrawal volumes and actual water withdrawals compared to monthly median, low, and high streamflows. Risk for biological stress was considered at 20% of long-term median and 10% of high- and low-flow thresholds. Future well build-out projections estimated potential for continued stress. Most water was permitted from small, free-flowing streams and "frack" ponds (dammed streams). Permitted 12-h pumping volumes exceeded median streamflow at 50% of withdrawal sites in June, when flows were low. Daily water usage, from operator disclosures, compared to median streamflow showed possible water stress in 7-51% of catchments from June-November, respectively. If 100% of produced water was recycled, per-well water use declined by 25%, reducing threshold exceedance by 10%. Future water stress was predicted to occur in fewer catchments important for drinking water and species of conservation concern due to the decline in new well installations and increased use of recycled water. Accessible and precise withdrawal and streamflow data are critical moving forward to assess and mitigate water stress in streams that experience high-volume withdrawals.

Exploring the role of flood transience in coarse bed load sediment transport

NASA Astrophysics Data System (ADS)

Phillips, C. B.; Singer, M. B.; Hill, K. M.; Paola, C.

2015-12-01

The rate of bed load transport under steady flow is known to vary both spatially and temporally due to various hydrologic and granular phenomena. Grain size distributions and riverbed properties (packing, imbrication, etc.) are known to affect flux for a particular value of applied flow stress, while hydrology is mainly assumed to control the magnitude of the applied bed stress above the threshold for bed material entrainment. The prediction of bed load sediment transport in field settings is further complicated by the inherent transience in flood hydrology, but little is known about how such flood transience influences bed load flux over a range of applied bed stress. Here we investigate the role of flood transience for gravel bed load transport through controlled laboratory experiments in a 28 m long 0.5 meter wide flume. We explore transient flow as the combination of unsteady and intermittent flow, where unsteady flow varies in magnitude over a given duration, and intermittent flow is characterized by turning the flow on and off. We systematically vary these details of flood hydrographs from one experiment to the next, and monitor the bed load as it varies with water discharge in real time by measuring sediment flux and tracking particles. We find that even with a narrow unimodal grain size distribution and constant sediment supply we observe hysteresis in bed load flux, different thresholds for entrainment and distrainment for the rising and falling limbs of a flood, and a threshold of entrainment that can vary one flood hydrograph to the next. Despite these complex phenomena we find that the total bed load transported for each flood plots along a linear trend with the integrated excess stress, consistent with prior field results. These results suggest that while the effects of transient flow and the shape of the hydrograph are measurable, they are second-order compared to the integrated excess stress.

Optogenetic control of RhoA reveals zyxin-mediated elasticity of stress fibres

NASA Astrophysics Data System (ADS)

Oakes, Patrick W.; Wagner, Elizabeth; Brand, Christoph A.; Probst, Dimitri; Linke, Marco; Schwarz, Ulrich S.; Glotzer, Michael; Gardel, Margaret L.

2017-06-01

Cytoskeletal mechanics regulates cell morphodynamics and many physiological processes. While contractility is known to be largely RhoA-dependent, the process by which localized biochemical signals are translated into cell-level responses is poorly understood. Here we combine optogenetic control of RhoA, live-cell imaging and traction force microscopy to investigate the dynamics of actomyosin-based force generation. Local activation of RhoA not only stimulates local recruitment of actin and myosin but also increased traction forces that rapidly propagate across the cell via stress fibres and drive increased actin flow. Surprisingly, this flow reverses direction when local RhoA activation stops. We identify zyxin as a regulator of stress fibre mechanics, as stress fibres are fluid-like without flow reversal in its absence. Using a physical model, we demonstrate that stress fibres behave elastic-like, even at timescales exceeding turnover of constituent proteins. Such molecular control of actin mechanics likely plays critical roles in regulating morphodynamic events.

Mixed convection flow of couple stress nanofluid over oscillatory stretching sheet with heat absorption/generation effects

NASA Astrophysics Data System (ADS)

Khan, Sami Ullah; Shehzad, Sabir Ali; Rauf, Amar; Ali, Nasir

2018-03-01

The aim of this article is to highlight the unsteady mixed convective couple stress nanoliquid flow passed through stretching surface. The flow is generated due to periodic oscillations of sheet. An appropriate set of dimensionless variables are used to reduce the independent variables in governing equations arising from mathematical modeling. An analytical solution has been computed by employing the technique of homotopy method. The outcomes of various sundry parameters like couple stress parameter, the ratio of angular velocity to stretching rate, thermophoresis parameter, Hartmann number, Prandtl number, heat source/sink parameter, Schmidt number described graphically and in tabular form. It is observed that the velocity profile increases by increasing mixed convection parameter and concentration buoyancy parameter. The temperature enhances for larger values of Hartmann number and Brownian. The concentration profile increases by increasing thermophoresis parameter. Results show that wall shear stress increases by increasing couple stress parameter and ratio of oscillating frequency to stretching rate.

Study of flow stress and spall strength of additively manufactured Ti-6-4 alloy

NASA Astrophysics Data System (ADS)

Cohen, Amitay; Paris, Vitaly; Yosef-Hai, Arnon; Gudinetsky, Eli; Tiferet, Eitan

2017-06-01

The use of additive manufacturing (AM) by Electron Beam Melting (EBM) or Selective Laser Melting (SLM) has extensively grown in the past few years. A major goal in AM is to manufacture materials with mechanical properties at least as good as traditionally manufactured materials. In this work we present results of planar impact tests and Split Hopkinson Pressure Bar tests (SHPB) on Ti-6-4 manufactured by EBM and SLM processes. Results of planar impact tests on SLM samples display slightly higher spall strength compared to EBM while the stress at Hugoniot elastic limit (HEL) is practically the same. Stress strain curves based on SHPB measurements at two different strain rates present similar plastic flow stresses for SLM and EBM processed Ti-6-4 alloy, while the flow stress is about 20% higher than reported for commercial reference material. The strain to failure of both materials shows considerable strain rate sensitivity. The results of post-mortem analysis of spall fracture will also be presented.

Evaluation of bed load transport subject to high shear stress fluctuations

NASA Astrophysics Data System (ADS)

Cheng, Nian-Sheng; Tang, Hongwu; Zhu, Lijun

2004-05-01

Many formulas available in the literature for computing sediment transport rates are often expressed in terms of time mean variables such as time mean bed shear stress or flow velocity, while effects of turbulence intensity, e.g., bed shear stress fluctuation, on sediment transport were seldom considered. This may be due to the fact that turbulence fluctuation is relatively limited in laboratory open-channel flows, which are often used for conducting sediment transport experiments. However, turbulence intensity could be markedly enhanced in practice. This note presents an analytical method to compute bed load transport by including effects of fluctuations in the bed shear stress. The analytical results obtained show that the transport rate enhanced by turbulence can be expressed as a simple function of the relative fluctuation of the bed shear stress. The results are also verified using data that were collected recently from specifically designed laboratory experiments. The present analysis is applicable largely for the condition of a flat bed that is comprised of uniform sand particles subject to unidirectional flows.

Rheological State Diagrams for Rough Colloids in Shear Flow.

PubMed

Hsiao, Lilian C; Jamali, Safa; Glynos, Emmanouil; Green, Peter F; Larson, Ronald G; Solomon, Michael J

2017-10-13

To assess the role of particle roughness in the rheological phenomena of concentrated colloidal suspensions, we develop model colloids with varying surface roughness length scales up to 10% of the particle radius. Increasing surface roughness shifts the onset of both shear thickening and dilatancy towards lower volume fractions and critical stresses. Experimental data are supported by computer simulations of spherical colloids with adjustable friction coefficients, demonstrating that a reduction in the onset stress of thickening and a sign change in the first normal stresses occur when friction competes with lubrication. In the quasi-Newtonian flow regime, roughness increases the effective packing fraction of colloids. As the shear stress increases and suspensions of rough colloids approach jamming, the first normal stresses switch signs and the critical force required to generate contacts is drastically reduced. This is likely a signature of the lubrication films giving way to roughness-induced tangential interactions that bring about load-bearing contacts in the compression axis of flow.

Rheological State Diagrams for Rough Colloids in Shear Flow

NASA Astrophysics Data System (ADS)

Hsiao, Lilian C.; Jamali, Safa; Glynos, Emmanouil; Green, Peter F.; Larson, Ronald G.; Solomon, Michael J.

2017-10-01

To assess the role of particle roughness in the rheological phenomena of concentrated colloidal suspensions, we develop model colloids with varying surface roughness length scales up to 10% of the particle radius. Increasing surface roughness shifts the onset of both shear thickening and dilatancy towards lower volume fractions and critical stresses. Experimental data are supported by computer simulations of spherical colloids with adjustable friction coefficients, demonstrating that a reduction in the onset stress of thickening and a sign change in the first normal stresses occur when friction competes with lubrication. In the quasi-Newtonian flow regime, roughness increases the effective packing fraction of colloids. As the shear stress increases and suspensions of rough colloids approach jamming, the first normal stresses switch signs and the critical force required to generate contacts is drastically reduced. This is likely a signature of the lubrication films giving way to roughness-induced tangential interactions that bring about load-bearing contacts in the compression axis of flow.

The Prominent Role of the Upstream Conditions on the Large-scale Motions of a Turbulent Channel Flow

NASA Astrophysics Data System (ADS)

Castillo, Luciano; Dharmarathne, Suranga; Tutkun, Murat; Hutchins, Nicholas

2017-11-01

In this study we investigate how upstream perturbations in a turbulent channel flow impact the downstream flow evolution, especially the large-scale motions. Direct numerical simulations were carried out at a friction Reynolds number, Reτ = 394 . Spanwise varying inlet blowing perturbations were imposed at 1 πh from the inlet. The flow field is decomposed into its constituent scales using proper orthogonal decomposition. The large-scale motions and the small-scale motions of the flow field are separated at a cut-off mode number, Mc. The cut-off mode number is defined as the number of the mode at which the fraction of energy recovered is 55 % . It is found that Reynolds stresses are increased due to blowing perturbations and large-scale motions are responsible for more than 70 % of the increase of the streamwise component of Reynolds normal stress. Surprisingly, 90 % of Reynolds shear stress is due to the energy augmentation of large-scale motions. It is shown that inlet perturbations impact the downstream flow by means of the LSM.

Strengthening and Plastic Flow of Ni3Al Alloy Microcrystals (Preprint)

DTIC Science & Technology

2012-08-01

the degree they can be re- solved ), with essentially no slip-band thickening. Note that the image of Fig. 4b has been digi- tally enhanced to better...solution hardening stress. The second term in Eqn. (2) represents a forest hardening contribution. Solving for the mi- crocrystal flow stress, one...but, the truncated glide lengths associated with the mean-field dis- location dynamics forces the stress to increase to re-scale the processes to the

A Modified Mechanical Threshold Stress Constitutive Model for Austenitic Stainless Steels

NASA Astrophysics Data System (ADS)

Prasad, K. Sajun; Gupta, Amit Kumar; Singh, Yashjeet; Singh, Swadesh Kumar

2016-12-01

This paper presents a modified mechanical threshold stress (m-MTS) constitutive model. The m-MTS model incorporates variable athermal and dynamic strain aging (DSA) Components to accurately predict the flow stress behavior of austenitic stainless steels (ASS)-316 and 304. Under strain rate variations between 0.01-0.0001 s-1, uniaxial tensile tests were conducted at temperatures ranging from 50-650 °C to evaluate the material constants of constitutive models. The test results revealed the high dependence of flow stress on strain, strain rate and temperature. In addition, it was observed that DSA occurred at elevated temperatures and very low strain rates, causing an increase in flow stress. While the original MTS model is capable of predicting the flow stress behavior for ASS, statistical parameters point out the inefficiency of the model when compared to other models such as Johnson Cook model, modified Zerilli-Armstrong (m-ZA) model, and modified Arrhenius-type equations (m-Arr). Therefore, in order to accurately model both the DSA and non-DSA regimes, the original MTS model was modified by incorporating variable athermal and DSA components. The suitability of the m-MTS model was assessed by comparing the statistical parameters. It was observed that the m-MTS model was highly accurate for the DSA regime when compared to the existing models. However, models like m-ZA and m-Arr showed better results for the non-DSA regime.

The Landlab v1.0 OverlandFlow component: a Python tool for computing shallow-water flow across watersheds

NASA Astrophysics Data System (ADS)

Adams, Jordan M.; Gasparini, Nicole M.; Hobley, Daniel E. J.; Tucker, Gregory E.; Hutton, Eric W. H.; Nudurupati, Sai S.; Istanbulluoglu, Erkan

2017-04-01

Representation of flowing water in landscape evolution models (LEMs) is often simplified compared to hydrodynamic models, as LEMs make assumptions reducing physical complexity in favor of computational efficiency. The Landlab modeling framework can be used to bridge the divide between complex runoff models and more traditional LEMs, creating a new type of framework not commonly used in the geomorphology or hydrology communities. Landlab is a Python-language library that includes tools and process components that can be used to create models of Earth-surface dynamics over a range of temporal and spatial scales. The Landlab OverlandFlow component is based on a simplified inertial approximation of the shallow water equations, following the solution of de Almeida et al.(2012). This explicit two-dimensional hydrodynamic algorithm simulates a flood wave across a model domain, where water discharge and flow depth are calculated at all locations within a structured (raster) grid. Here, we illustrate how the OverlandFlow component contained within Landlab can be applied as a simplified event-based runoff model and how to couple the runoff model with an incision model operating on decadal timescales. Examples of flow routing on both real and synthetic landscapes are shown. Hydrographs from a single storm at multiple locations in the Spring Creek watershed, Colorado, USA, are illustrated, along with a map of shear stress applied on the land surface by flowing water. The OverlandFlow component can also be coupled with the Landlab DetachmentLtdErosion component to illustrate how the non-steady flow routing regime impacts incision across a watershed. The hydrograph and incision results are compared to simulations driven by steady-state runoff. Results from the coupled runoff and incision model indicate that runoff dynamics can impact landscape relief and channel concavity, suggesting that, on landscape evolution timescales, the OverlandFlow model may lead to differences in simulated topography in comparison with traditional methods. The exploratory test cases described within demonstrate how the OverlandFlow component can be used in both hydrologic and geomorphic applications.

An abbreviated Reynolds stress turbulence model for airfoil flows

NASA Technical Reports Server (NTRS)

Gaffney, R. L., Jr.; Hassan, H. A.; Salas, M. D.

1990-01-01

An abbreviated Reynolds stress turbulence model is presented for solving turbulent flow over airfoils. The model consists of two partial differential equations, one for the Reynolds shear stress and the other for the turbulent kinetic energy. The normal stresses and the dissipation rate of turbulent kinetic energy are computed from algebraic relationships having the correct asymptotic near wall behavior. This allows the model to be integrated all the way to the wall without the use of wall functions. Results for a flat plate at zero angle of attack, a NACA 0012 airfoil and a RAE 2822 airfoil are presented.

Nonlinear saturation of the Rayleigh instability due to oscillatory flow in a liquid-lined tube

NASA Astrophysics Data System (ADS)

Halpern, David; Grotberg, James B.

2003-10-01

In this paper, the stability of core annular flows consisting of two immiscible fluids in a cylindrical tube with circular cross-section is examined. Such flows are important in a wide range of industrial and biomedical applications. For example, in secondary oil recovery, water is pumped into the well to displace the remaining oil. It is also of relevance in the lung, where a thin liquid film coats the inner surface of the small airways of the lungs. In both cases, the flow is influenced by a surface-tension instability, which may induce the breakup of the core fluid into short plugs, reducing the efficiency of the oil recovery, or blocking the passage of air in the lung thus inducing airway closure. We consider the stability of a thin film coating the inner surface of a rigid cylindrical tube with the less viscous fluid in the core. For thick enough films, the Rayleigh instability forms a liquid bulge that can grow to eventually create a plug blocking the tube. The analysis explores the effect of an oscillatory core flow on the interfacial dynamics and particularly the nonlinear stabilization of the bulge. The oscillatory core flow exerts tangential and normal stresses on the interface between the two fluids that are simplified by uncoupling the core and film analyses in the thin-film high-frequency limit of the governing equations. Lubrication theory is used to derive a nonlinear evolution equation for the position of the air liquid interface which includes the effects of the core flow. It is shown that the core flow can prevent plug formation of the more viscous film layer by nonlinear saturation of the capillary instability. The stabilization mechanism is similar to that of a reversing butter knife, where the core shear wipes the growing liquid bulge back on to the tube wall during the main tidal volume stroke, but allows it to grow back as the stoke and shear turn around. To be successful, the leading film thickness ahead of the bulge must be smaller than the trailing film thickness behind it, a requirement necessitating a large enough core capillary number which promotes a large core shear stress on the interface. The core capillary number is defined to be the ratio of core viscous forces to surface tension forces. When this process is tuned correctly, the two phases balance and there is no net growth of the liquid bulge over one cycle. We find that there is a critical frequency above which plug formation does not occur, and that this critical frequency increases as the tidal volume amplitude of the core flow decreases.

Oscillatory slip flow past a spherical inclusion embedded in a Brinkman medium

NASA Astrophysics Data System (ADS)

Palaniappan, D.

2016-11-01

Non-steady flow past an impermeable sphere embedded in a porous medium is investigated based on Brinkman model with Navier slip conditions. Exact analytic solution for the stream-function - involving modified Bessel function of the second kind - describing the slow oscillatory flow around a rigid spherical inclusion is obtained in the limit of low-Reynolds-number. The key parameters such as the frequency of oscillation λ, the permeability constant δ, and the slip coefficient ξ control the flow fields and physical quantities in the entire flow domain. Local streamlines for fixed times demonstrate the variations in flow patterns. Closed form expressions for the tangential velocity profile, wall shear stress, and the force acting on the sphere are computed and compared with the existing results. It is noted that the slip parameter in the range 0 <= ξ <= 0 . 5 has a significant effect in reducing the stress and force. The steady-state velocity overshoot behavior in the vicinity of the sphere is re-iterated. In the limit of large permeability, Darcy (potential) flow is recovered outside a boundary layer. The results are of some interest in predicting maximum wall stress and pressure drop associated with biological models in fibrous media.

Jetting of a shear banding fluid in rectangular ducts

PubMed Central

Salipante, Paul F.; Little, Charles A. E.; Hudson, Steven D.

2017-01-01

Non-Newtonian fluids are susceptible to flow instabilities such as shear banding, in which the fluid may exhibit a markedly discontinuous viscosity at a critical stress. Here we report the characteristics and causes of a jetting flow instability of shear banding wormlike micelle solutions in microfluidic channels with rectangular cross sections over an intermediate volumetric flow regime. Particle-tracking methods are used to measure the three-dimensional flow field in channels of differing aspect ratios, sizes, and wall materials. When jetting occurs, it is self-contained within a portion of the channel where the flow velocity is greater than the surroundings. We observe that the instability forms in channels with aspect ratio greater than 5, and that the location of the high-velocity jet appears to be sensitive to stress localizations. Jetting is not observed in a lower concentration solution without shear banding. Simulations using the Johnson-Segalman viscoelastic model show a qualitatively similar behavior to the experimental observations and indicate that compressive normal stresses in the cross-stream directions support the development of the jetting flow. Our results show that nonuniform flow of shear thinning fluids can develop across the wide dimension in rectangular microfluidic channels, with implications for microfluidic rheometry. PMID:28691108

Investigation of secondary flows in turbulent pipe flows with three-dimensional sinusoidal walls

NASA Astrophysics Data System (ADS)

Chan, Leon; MacDonald, Michael; Chung, Daniel; Hutchins, Nicholas; Ooi, Andrew

2017-11-01

The occurrence of secondary flows is systematically investigated via Direct Numerical Simulations (DNS) of turbulent flow in a rough wall pipe at friction Reynolds numbers of 540. In this study, the peak-to-trough height of the roughness elements, which consist of three-dimensional sinusoidal roughness, is fixed at 120 viscous units while the wavelength of the roughness elements is varied. The solidity or effective slope (ES) of the roughness ranges from the sparse regime (ES = 0.18) to the closely packed roughness/dense regime (ES = 0.72). The time-independent dispersive stresses, which arise due to the stationary features of the flow, are analysed and are found to increase with increasing roughness wavelength. These dispersive stresses are related to the occurrence of secondary flows and are maximum within the roughness canopy. Above the crest of the roughness elements, the dispersive stresses reduce to zero at wall-normal heights greater than half of the roughness wavelength. This study has found that the size and wall-normal extent of the secondary flows scales with the roughness wavelength and can reach wall-normal heights of almost half of the pipe radius.

Visualization of Flow in Pressurizer Spray Line Piping and Estimation of Thermal Stress Fluctuation Caused by Swaying of Water Surface

NASA Astrophysics Data System (ADS)

Oumaya, Toru; Nakamura, Akira; Onojima, Daisuke; Takenaka, Nobuyuki

The pressurizer spray line of PWR plants cools reactor coolant by injecting water into pressurizer. Since the continuous spray flow rate during commercial operation of the plant is considered insufficient to fill the pipe completely, there is a concern that a water surface exists in the pipe and may periodically sway. In order to identify the flow regimes in spray line piping and assess their impact on pipe structure, a flow visualization experiment was conducted. In the experiment, air was used substituted for steam to simulate the gas phase of the pressurizer, and the flow instability causing swaying without condensation was investigated. With a full-scale mock-up made of acrylic, flow under room temperature and atmospheric pressure conditions was visualized, and possible flow regimes were identified based on the results of the experiment. Three representative patterns of swaying of water surface were assumed, and the range of thermal stress fluctuation, when the surface swayed instantaneously, was calculated. With the three patterns of swaying assumed based on the visualization experiment, it was confirmed that the thermal stress amplitude would not exceed the fatigue endurance limit prescribed in the Japanese Design and Construction Code.

STUDIES ON THE ANOMALOUS VISCOSITY AND FLOW-BIREFRINGENCE OF PROTEIN SOLUTIONS

PubMed Central

Lawrence, A. S. C.; Miall, Margaret; Needham, Joseph; Shen, Shih-Chang

1944-01-01

1. An extensive investigation has been made of protein particle shape using the methods of flow-birefringence and anomalous viscosity measurement in the coaxial cell. 2. As a result of investigations on a number of proteins, it is concluded that they may be divided into four groups. Group A consists of those which show flow-anomaly both in the bulk phase and in the surface film. These also show flow-birefringence in the bulk phase. Examples: tobacco mosaic disease virus nucleoprotein; myosin. Though corpuscular proteins, they have elongated particles before denaturation. Group B consists of those which show flow-anomaly only (in the first instance) in the surface film, and no flow-birefringence in the bulk phase. They are probably close to spherical in shape in solution, but form elongated particles as they denature in the surface film. After this process has been completed, they may show flow-anomaly also in the bulk phase. Some proteins show flow-anomaly in the surface film immediately it forms, others only show it after a certain time has elapsed for the building up of the film. We designate the former as group B1 and the latter as group B2. Group B1, immediate surface film flow-anomaly. Examples: serum euglobulin, amphibian embryo euglobulin b. Group B2, slowly appearing surface film flow-anomaly. After the film has once been fully formed and then dispersed by shaking, the solution may have the properties of that of a protein in group B1; i.e., anomalous flow in the film may occur immediately on testing in the viscosimeter. Examples: avian ovalbumin, amphibian embryo pseudoglobulin. Group C consists of those proteins which show flow-anomaly neither in the bulk phase nor in the surface film, under the conditions used by us. They are probably close to spherical in shape. Examples: insulin, methaemoglobin, amphibian embryo euglobulin c, mucoproteins. 3. The theoretical significance of protein fibre molecules, whether native or formed by denaturation in the living cell, is discussed, especially in relation to experimental morphology and cytology. PMID:19873385

Investigation of Thermal Stress Convection in Nonisothermal Gases under Microgravity Conditions

NASA Technical Reports Server (NTRS)

Mackowski, Daniel W.

1999-01-01

The project has sought to ascertain the veracity of the Burnett relations, as applied to slow moving, highly nonisothermal gases, by comparison of convection and stress predictions with those generated by the DSMC method. The Burnett equations were found to provide reasonable descriptions of the pressure distribution and normal stress in stationary gases with a 1-D temperature gradient. Continuum/Burnett predictions of thermal stress convection in 2-D heated enclosures, however, are not quantitatively supported by DSMC results. For such situations, it appears that thermal creep flows, generated at the boundaries of the enclosure, will be significantly larger than the flows resulting from thermal stress in the gas.

Anisotropic constitutive modeling for nickel base single crystal superalloys using a crystallographic approach

NASA Technical Reports Server (NTRS)

Stouffer, D. C.; Sheh, M. Y.

1988-01-01

A micromechanical model based on crystallographic slip theory was formulated for nickel-base single crystal superalloys. The current equations include both drag stress and back stress state variables to model the local inelastic flow. Specially designed experiments have been conducted to evaluate the effect of back stress in single crystals. The results showed that (1) the back stress is orientation dependent; and (2) the back stress state variable in the inelastic flow equation is necessary for predicting anelastic behavior of the material. The model also demonstrated improved fatigue predictive capability. Model predictions and experimental data are presented for single crystal superalloy Rene N4 at 982 C.

Comparison of superhydrophobic drag reduction between turbulent pipe and channel flows

NASA Astrophysics Data System (ADS)

Im, Hyung Jae; Lee, Jae Hwa

2017-09-01

It has been known over several decades that canonical wall-bounded internal flows of a pipe and channel share flow similarities, in particular, close to the wall due to the negligible curvature effect. In the present study, direct numerical simulations of fully developed turbulent pipe and channel flows are performed to investigate the influence of the superhydrophobic surfaces (SHSs) on the turbulence dynamics and the resultant drag reduction (DR) of the flows under similar conditions. SHSs at the wall are modeled in spanwise-alternating longitudinal regions with a boundary with no-slip and shear-free conditions, and the two parameters of the spanwise periodicity (P/δ) and SHS fraction (GF) within a pitch are considered. It is shown, in agreement with previous investigations in channels, that the turbulent drag for the pipe and channel flows over SHSs is continuously decreased with increases in P/δ and GF. However, the DR rate in the pipe flows is greater than that in the channel flows with an accompanying reduction of the Reynolds stress. The enhanced performance of the DR for the pipe flow is attributed to the increased streamwise slip and weakened Reynolds shear stress contributions. In addition, a mathematical analysis of the spanwise mean vorticity equation suggests that the presence of a strong secondary flow due to the increased spanwise slip of the pipe flows makes a greater negative contribution of advective vorticity transport than the channel flows, resulting in a higher DR value. Finally, an inspection of the origin of the mean secondary flow in turbulent flows over SHSs based on the spatial gradients of the turbulent kinetic energy demonstrates that the secondary flow is both driven and sustained by spatial gradients in the Reynolds stress components, i.e., Prandtl's secondary flow of the second kind.

Ion implantation disorder in strained-layer superlattices

NASA Astrophysics Data System (ADS)

Arnold, G. W.; Picraux, S. T.; Peercy, P. S.; Myers, D. R.; Biefeld, R. M.; Dawson, L. R.

Cantilever beam bending and RBS channeling measurements have been used to examine implantation induced disorder and stress buildup in InO 2GaO 8As/GaAs SLS structures. The critical fluence for saturation of compressive stress occurs prior to amorphous layer formation and is followed by stress relief. For all the ions the maximum ion induced stress scales with energy density into atomic processes and stress relief occurs above approximately 1x10 to the 20th keV/1 cubic cm. Stress relief is more pronounced for the SLSs than for bulk GaAs. Stress relief may lead to slip or other forms of inelastic material flow in SLSs, which would be undesirable for active regions in device applications. Such material flow may be avoided by limiting maximum fluences or by multiple step or simultaneous implantation and annealing for high fluences.

The Azimuth Structure of Nuclear Collisions — I

NASA Astrophysics Data System (ADS)

Trainor, Thomas A.; Kettler, David T.

We describe azimuth structure commonly associated with elliptic and directed flow in the context of 2D angular autocorrelations for the purpose of precise separation of so-called nonflow (mainly minijets) from flow. We extend the Fourier-transform description of azimuth structure to include power spectra and autocorrelations related by the Wiener-Khintchine theorem. We analyze several examples of conventional flow analysis in that context and question the relevance of reaction plane estimation to flow analysis. We introduce the 2D angular autocorrelation with examples from data analysis and describe a simulation exercise which demonstrates precise separation of flow and nonflow using the 2D autocorrelation method. We show that an alternative correlation measure based on Pearson's normalized covariance provides a more intuitive measure of azimuth structure.

Research on the Stress and Material Flow with Single Particle—Simulations and Experiments

NASA Astrophysics Data System (ADS)

Zhang, Tao; Jiang, Feng; Yan, Lan; Xu, Xipeng

2017-04-01

The scratching process of particle is a complex material removal process involving cutting, plowing, and rubbing. In this study, scratch experiments under different loads are performed on a multifunctional tester for material surface. Natural diamond and Fe-Cr-Ni stainless steel are chosen as indenter and workpiece material, respectively. The cutting depth and side flow height of scratch are measured using a white light interferometer. The finite element model is developed, and the numerical simulation of scratching is conducted using AdvantEdgeTM. The simulated forces and side flow height under different cutting depths correspond well with experimental results, validating the accuracy of the scratching simulation. The mises stress distribution of the particle is presented, with the maximum stress occurring inside the particle rather than on the surface. The pressure distribution of the particle is also given, and results show that the maximum pressure occurs on the contact surface of particle and workpiece. The material flow contour is presented, and material flow direction and velocity magnitude are analyzed.

Influence of strain rate and temperature on tensile properties and flow behaviour of a reduced activation ferritic-martensitic steel

NASA Astrophysics Data System (ADS)

Vanaja, J.; Laha, K.; Sam, Shiju; Nandagopal, M.; Panneer Selvi, S.; Mathew, M. D.; Jayakumar, T.; Rajendra Kumar, E.

2012-05-01

Tensile strength and flow behaviour of a Reduced Activation Ferritic-Martensitic (RAFM) steel (9Cr-1W-0.06Ta-0.22V-0.08C) have been investigated over a temperature range of 300-873 K at different strain rates. Tensile strength of the steel decreased with temperature and increased with strain rate except at intermediate temperatures. Negative strain rate sensitivity of flow stress of the steel at intermediate temperatures revealed the occurrence of dynamic strain ageing in the steel, even though no serrated flow was observed. The tensile flow behaviour of the material was well represented by the Voce strain hardening equation for all the test conditions. Temperature and strain rate dependence of the various parameters of Voce equation were interpreted with the possible deformation mechanisms. The equivalence between the saturation stress at a given strain rate in tensile test and steady state deformation rate at a given stress in creep test was found to be satisfied by the RAFM steel.

Effects of wear and service conditions on residual stresses in commuter car wheels

DOT National Transportation Integrated Search

2004-09-01

This paper illustrates application of the shakedown residual stress estimation technique to : assess the effects of service conditions on wheel residual stresses. The examples described provide the : technical details on how the technique is practica...

Effect of shear stress on the migration of hepatic stellate cells.

PubMed

Sera, Toshihiro; Sumii, Tateki; Fujita, Ryosuke; Kudo, Susumu

2018-01-01

When the liver is damaged, hepatic stellate cells (HSCs) can change into an activated, highly migratory state. The migration of HSCs may be affected by shear stress due not only to sinusoidal flow but also by the flow in the space of Disse because this space is filled with blood plasma. In this study, we evaluated the effects of shear stress on HSC migration in a scratch-wound assay with a parallel flow chamber. At regions upstream of the wound area, the migration was inhibited by 0.6 Pa and promoted by 2.0 Pa shear stress, compared to the static condition. The platelet-derived growth factor (PDGF)-BB receptor, PDGFR-β, was expressed in all conditions and the differences were not significant. PDGF increased HSC migration, except at 0.6 Pa shear stress, which was still inhibited. These results indicate that another molecular factor, such as PDGFR-α, may act to inhibit the migration under low shear stress. At regions downstream of the wound area, the migration was smaller under shear stress than under the static condition, although the expression of PDGFR-β was significantly higher. In particular, the migration direction was opposite to the wound area under high shear stress; therefore, migration might be influenced by the intercellular environment. Our results indicate that HSC migration was influenced by shear stress intensity and the intercellular environment.

Prospectus

PubMed Central

Parsons, Peter A.

2009-01-01

Free living organisms typically occur in harsh environments challenged by abiotic stresses of varying intensities. Taking ionizing radiation and caloric restriction as examples, environmental variation from benign to extreme gives a fitness-stress continuum where energetic efficiency, a measure of fitness, is inversely related to stress level. Hormesis occurs in benign regions for these examples. In contrast aging emphasizes survival towards the limits of survival under accumulating stress from Reactive Oxygen Species, ROS. An energetic evolutionary approach underlies an ecological aging theory based principally upon survival, which incorporates hormesis. Multiple environmental agents contributing to hormesis should be considered by those attempting to improve the quality of life by delaying the onset of senescence, so enhancing survival. Caloric restriction has wider acceptance in this process than ionizing radiation. PMID:20221282

Stress Response Mechanisms: From Single Cells to Multinational Organizations

PubMed Central

Pech, Richard J.

2006-01-01

Can a literal comparison be made between biological phenomena in organisms and phenomena in human organizations? The evidence provided by simplified but useful examples appears to suggest that a phenomenon simulating hormesis can and does occur in organizational contexts. Similarities between stress response behaviors of organisms and stress response behaviors in organizations are discussed. Cellular stress response mechanisms stimulate and repair, as well as defend the organism against further attacks. Organizational hormesis describes actions that stimulate the organization by increasing its focus and protecting it against future attacks. The common aim for the organism as well as the organization is to increase the probability of survival. The following describes examples of organizational survival that demonstrate a number of hormetic parallels between organisms and organisations. PMID:18648597

Approximation of Viscoelastic Stresses from Newtonian Turbulent Kinematics

DTIC Science & Technology

1988-09-01

birefringence of polyethylene oxide solutions in a four roll mill. J.Poly.Sci.:Poly.Phys.Ed. 14, 1111-1119. Dandridge, A., Meeten , G.H., Layec-Raphalen, M.N...flows. Poly. Comm. 25, 144-146. Metzner, A.B., & Astarita, G . 1967 External flow of viscoelastic materials: fluid property restrictions on the use of...dumbbell model for dilute solutions. Rheol.Acta 23, 151-162. Philippoff, W. 1956 Flow-birefringence and stress. Nature 178 , 811-812. Ryskin, G . 1987a

Combined Stresses in the Workplace, Survey of State of Published Knowledge.

DTIC Science & Technology

1982-10-01

as function of temp. Gz tol.was not lost if heated and hydrated. Related to changes in retinal blood flow and water balance 19. KEY WOOS P...when baroceptor reflexes have time to act with GOR, these can’t hold cerebral blood flow at * . suitable levels. It. KEY WORDS acceleration...hyponatremia, combined stresses, blood volume, grayout, sodium deprivation, blood flow , interactive responses 20. F40TES OD 0 1473 (MOO.) REPORT DOCUMENTATION

Predicting equilibrium states with Reynolds stress closures in channel flow and homogeneous shear flow

NASA Technical Reports Server (NTRS)

Abid, R.; Speziale, C. G.

1993-01-01

Turbulent channel flow and homogeneous shear flow have served as basic building block flows for the testing and calibration of Reynolds stress models. A direct theoretical connection is made between homogeneous shear flow in equilibrium and the log-layer of fully-developed turbulent channel flow. It is shown that if a second-order closure model is calibrated to yield good equilibrium values for homogeneous shear flow it will also yield good results for the log-layer of channel flow provided that the Rotta coefficient is not too far removed from one. Most of the commonly used second-order closure models introduce an ad hoc wall reflection term in order to mask deficient predictions for the log-layer of channel flow that arise either from an inaccurate calibration of homogeneous shear flow or from the use of a Rotta coefficient that is too large. Illustrative model calculations are presented to demonstrate this point which has important implications for turbulence modeling.

Predicting equilibrium states with Reynolds stress closures in channel flow and homogeneous shear flow

NASA Technical Reports Server (NTRS)

Abid, R.; Speziale, C. G.

1992-01-01

Turbulent channel flow and homogeneous shear flow have served as basic building block flows for the testing and calibration of Reynolds stress models. A direct theoretical connection is made between homogeneous shear flow in equilibrium and the log-layer of fully-developed turbulent channel flow. It is shown that if a second-order closure model is calibrated to yield good equilibrium values for homogeneous shear flow it will also yield good results for the log-layer of channel flow provided that the Rotta coefficient is not too far removed from one. Most of the commonly used second-order closure models introduce an ad hoc wall reflection term in order to mask deficient predictions for the log-layer of channel flow that arise either from an inaccurate calibration of homogeneous shear flow or from the use of a Rotta coefficient that is too large. Illustrative model calculations are presented to demonstrate this point which has important implications for turbulence modeling.

Method and apparatus for monitoring characteristics of a flow path having solid components flowing therethrough

DOEpatents

Hoskinson, Reed L [Rigby, ID; Svoboda, John M [Idaho Falls, ID; Bauer, William F [Idaho Falls, ID; Elias, Gracy [Idaho Falls, ID

2008-05-06

A method and apparatus is provided for monitoring a flow path having plurality of different solid components flowing therethrough. For example, in the harvesting of a plant material, many factors surrounding the threshing, separating or cleaning of the plant material and may lead to the inadvertent inclusion of the component being selectively harvested with residual plant materials being discharged or otherwise processed. In accordance with the present invention the detection of the selectively harvested component within residual materials may include the monitoring of a flow path of such residual materials by, for example, directing an excitation signal toward of flow path of material and then detecting a signal initiated by the presence of the selectively harvested component responsive to the excitation signal. The detected signal may be used to determine the presence or absence of a selected plant component within the flow path of residual materials.

A new sensor for stress measurement based on blood flow fluctuations

NASA Astrophysics Data System (ADS)

Fine, I.; Kaminsky, A. V.; Shenkman, L.

2016-03-01

It is widely recognized that effective stress management could have a dramatic impact on health care and preventive medicine. In order to meet this need, efficient and seamless sensing and analytic tools for the non-invasive stress monitoring during daily life are required. The existing sensors still do not meet the needs in terms of specificity and robustness. We utilized a miniaturized dynamic light scattering sensor (mDLS) which is specially adjusted to measure skin blood flow fluctuations and provides multi- parametric capabilities. Based on the measured dynamic light scattering signal from the red blood cells flowing in skin, a new concept of hemodynamic indexes (HI) and oscillatory hemodynamic indexes (OHI) have been developed. This approach was utilized for stress level assessment for a few usecase scenario. The new stress index was generated through the HI and OHI parameters. In order to validate this new non-invasive stress index, a group of 19 healthy volunteers was studied by measuring the mDLS sensor located on the wrist. Mental stress was induced by using the cognitive dissonance test of Stroop. We found that OHIs indexes have high sensitivity to the mental stress response for most of the tested subjects. In addition, we examined the capability of using this new stress index for the individual monitoring of the diurnal stress level. We found that the new stress index exhibits similar trends as reported for to the well-known diurnal behavior of cortisol levels. Finally, we demonstrated that this new marker provides good sensitivity and specificity to the stress response to sound and musical emotional arousal.

Occupational status and job stress in relation to cardiovascular stress reactivity in Japanese workers.

PubMed

Hirokawa, Kumi; Ohira, Tetsuya; Nagayoshi, Mako; Kajiura, Mitsugu; Imano, Hironori; Kitamura, Akihiko; Kiyama, Masahiko; Okada, Takeo; Iso, Hiroyasu

2016-12-01

This study aimed to investigate the effects of occupational status and job stress factors on cardiovascular stress reactivity in Japanese workers. In this baseline assessment between 2001 and 2009 in Osaka, Japan, we examined 928 healthy Japanese employees (330 men, 598 women) from two occupational statuses: managers/professionals and general workers. A brief job stress questionnaire was used to evaluate job stress levels. Systolic and diastolic blood pressure (SBP, DBP), heart rate, heart rate variability (high-frequency [HF], low-frequency [LF], LF/HF], and peripheral blood flow were measured at rest and during two stressful tasks. Changes in stress reactivity were calculated as the difference between the measured variables during the tasks and the rest period. Men showed inverse associations between quantitative job overload and DBP, heart rate, and LF/HF, between physical demands and blood pressure (SBP, DBP), and between a poor physical environment and HF. Men also had positive associations between qualitative job overload and heart rate, and between physical demands and peripheral blood flow (all p < 0.05). Women showed inverse associations between qualitative job overload and SBP, and showed positive associations between qualitative job overload and peripheral blood flow, and between a poor physical environment and SBP (all p < 0.05). When stratified by occupational status, significant associations between job stress and changes in stress reactivity were observed in male managers/professionals and female general workers (p < 0.05). Job stress levels are associated with changes in cardiovascular stress reactivity in men and women. Occupational status may modify these associations.